id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
cord-297178-moxhk2e0	Novaes Rocha, Vinicius	Viral replication of SARS-CoV-2 could be self-limitative - the role of the renin-angiotensin system on COVID-19 pathophysiology	2020-10-01		.txt	text/plain	3277	115	35	Therefore individuals with greater expression of tissue ACE, and consequently, greater production of Ang II, will present a decrease in tissue ACE2 and an increase in soluble ACE2 (systemic), due to greater activation of ADAM17 and ACE2 cleavage. Thus, due to higher levels of circulating ACE2, men may present a lower level of tissue ACE2, becoming more vulnerable to local SARS imbalance after SARS-Cov-2 infection.	cache/cord-297178-moxhk2e0.txt	txt/cord-297178-moxhk2e0.txt
