id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
cord-331428-6pvr2vew	Heffernan, Kevin S.	Exercise as medicine for COVID-19: on PPAR with emerging pharmacotherapy	2020-08-17		.txt	text/plain	1837	46	11	Expression of peroxisome proliferatoractivated receptor alpha (PPAR alpha) in primary cultures of human vascular endothelial cells Fatty acid carbon is essential for dNTP synthesis in endothelial cells A Protective Effect of PPARα in Endothelial Progenitor Cells Through Regulating Metabolism PPARalpha and GR differentially down-regulate the expression of nuclear factor-kappaB-responsive genes in vascular endothelial cells NAD(P)H oxidase/nitric oxide interactions in peroxisome proliferator activated receptor (PPAR)alpha-mediated cardiovascular effects Fenofibrate suppresses microvascular inflammation and apoptosis through adenosine monophosphate-activated protein kinase activation Fenofibrate activates AMPK and increases eNOS phosphorylation in HUVEC The peroxisome proliferator-activated receptor α agonist fenofibrate decreases airway reactivity to methacholine and increases endothelial nitric oxide synthase phosphorylation in mouse lung PPARalpha activators upregulate eNOS activity and inhibit cytokine-induced NF-kappaB activation through AMP-activated protein kinase activation Peroxisome Proliferator-Activated Receptor α Agonists Increase Nitric Oxide Synthase Expression in Vascular Endothelial Cells PPAR-α Agonist Fenofibrate Upregulates Tetrahydrobiopterin Level through Increasing the Expression of Guanosine 5'-Triphosphate Cyclohydrolase-I in Human Umbilical Vein Endothelial Cells Effect of fenofibrate on serum nitric oxide levels in patients with hypertriglyceridemia, Advances in clinical and experimental medicine : official organ Fenofibrate improves vascular endothelial function by reducing oxidative stress while increasing endothelial nitric oxide synthase in healthy normolipidemic older adults Fibrate therapy and flow-mediated dilation: A systematic review and meta-analysis of randomized placebocontrolled trials Strong Relationship Between Vascular Function in the Coronary and Brachial Arteries Peripheral Vascular Endothelial Function And The Pulmonary Blood Pressure Response To Exercise In Pulmonary Hypertension Coronary flow velocity reserve is improved by PPAR-α agonist fenofibrate in patients with hypertriglyceridemia Fenofibrate improves cerebral blood flow after middle cerebral artery occlusion in mice PPARα activation improves endothelial dysfunction and reduces fibrosis and portal pressure in cirrhotic rats Effects of the PPAR-α agonist fenofibrate on acute and short-term consequences of brain ischemia Effect of endurance training on lipid metabolism in women: a potential role for PPARalpha in the metabolic response to training Transcriptional adaptations of lipid metabolism in tibialis anterior muscle of endurance-trained athletes Vascular effects of exercise: endothelial adaptations beyond active muscle beds Exercise modalities and endothelial function: a systematic review and dose-response meta-analysis of randomized controlled trials, Sports medicine The antiinflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease Physical exercise as a tool to help the immune system against COVID-19: an integrative review of the current literature Prevention of age-related endothelial dysfunction by habitual aerobic exercise in healthy humans: possible role of nuclear factor κB Adolph Distinguished Lecture: The remarkable anti-aging effects of aerobic exercise on systemic arteries Effects of exercise training on endothelial progenitor cells in cardiovascular disease: a systematic review PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. This paper will explore the hypothesis that exercise may be a useful adjuvant in a setting of COVID-19 management/rehabilitation due to its effects on PPARα and vascular endothelial function.	cache/cord-331428-6pvr2vew.txt	txt/cord-331428-6pvr2vew.txt
