Layout 1 ISDS Annual Conference Proceedings 2012. This is an Open Access article distributed under the terms of the Creative Commons Attribution- Noncommercial 3.0 Unported License (http://creativecommons.org/licenses/by-nc/3.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ISDS 2012 Conference Abstracts Enabling Syndromic Surveillance in Pakistan Ross Maciejewski*1, Shehzad Afzal2, Adam J. Fairfield1, Arif Ghafoor2, David S. Ebert2, Naeem Ayyaz4 and Maaz Ahmed3 1Computer Science, Arizona State University, Tempe, AZ, USA; 2Purdue University, West Lafayette, IN, USA; 3King Edward Medical University, Lahore, Pakistan; 4University of Engineering and Technology, Lahore, Pakistan Objective This work presents our first steps in developing a Global Real-time Infectious Disease Surveillance System (GRIDDS) employing robust and novel in-fectious disease epidemiology models with real-time in- ference and pre/exercise planning capabilities for Lahore, Pakistan. The objective of this work is to address the infectious disease sur- veillance challenges (specific to developing countries such as Pak- istan) and develop a collaborative capability for monitoring and managing outbreaks of natural or manmade infectious diseases in Pakistan. Methods Utilizing our partner hospitals in the Lahore, Punjab area, we have begun developing a theoretical model of patient hospital visits with respect to diseases and syndromes within Pakistan. Our first thrust has focused on the collection, categorization and cleansing of data based on expert knowledge from our partnering institutions in Pak- istan. Data consists of a patient’s home address and chief complaint which is then categorized into syndromes. Home addresses are geocoded utilizing the Google API with a resultant 72% accuracy. Unknown geolocations are aggregated only at the hospital level. Using this cleaned data, we employ methods similar to our previous work [1] on syndromic surveillance for early disease detection. Cur- rently, we have collected over 600,000 patient records over 1.5 years. We employ the use of choropleth maps, isopleth maps utilizing kernel density estimation of patient addresses, traditional control chart methods such as exponentially weighted moving averages (EWMA), and a non-parametric time series analysis approach (sea- sonal trend decomposition using loess smoothing (STL) [2]) which requires only 90 days of historical data to be put into operation. The time series models are deployed as part of a real-time surveillance system in which temporal anomalies over regions can be analyzed and disease outbreaks reported. Results Figure 1 illustrates our visual analytics toolkit in operation. Here we see the location of our partner hospital in the Lahore region. The hospital coverage is in the most populous location of the city, pro- viding data as a sentinel site for the overall health of the city. Cur- rently, our system employs the use of interactive filters and linked isopleth or choropleth maps with time series analysis on mouse over. Conclusions Currently our research has focused on one partner location within the city of Lahore. Our ongoing work is focusing on the adoption of such a system to other regions of the country and the development of disease spread simulations (particularly Dengue Fever) utilizing base- line data collected by our partners. We plan to integrate these models into our visual analytics system for real-time planning and simula- tion. Keywords syndromic surveillance; visual analytics; pakistan Acknowledgments This work is supported by the Defense Threat Reduction Agency Award Number HDTRA1-10-1-0083. References [1] Maciejewski, R., et al.., “Forecasting Hotspot – A Predictive Analyt- ics Approach,” IEEE Transactions on Visualization and Computer Graphics, 17(4): 440-453, 2011. [2] Hafen, R. P., et al., “Syndromic surveillance: STL modeling, visual- izing and monitoring disease counts,” BMC Medical Informatics and Decision Making, 2009. *Ross Maciejewski E-mail: rmacieje@asu.edu Online Journal of Public Health Informatics * ISSN 1947-2579 * http://ojphi.org * 5(1):e106, 2013