Layout 1 ISDS Annual Conference Proceedings 2012. This is an Open Access article distributed under the terms of the Creative Commons Attribution- Noncommercial 3.0 Unported License (http://creativecommons.org/licenses/by-nc/3.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ISDS 2012 Conference Abstracts Malaria Trends in Six Outpatient Sites in Uganda, 2008— 2011 Ruth K. Nassali*1, Arthur Mpimbaza1, Stella Kakeeto1, Asadu Sserwanga1, Fred Kizito1, Denis Rubahika2, Melody Miles3, Michelle Chang3, Grant Dorsey4 and Moses Kamya1 1Infectious Diseases Research Collaboration, Kampala, Uganda; 2National Malaria Control Program, Kampala, Uganda; 3Centers for Disease Control, Atlanta, GA, USA; 4Univeristy of California, San Francisco, San Francisco, CA, USA Objective To estimate trends in malaria morbidity at six sentinel sites in Uganda. Introduction Over the past five years, efforts to control malaria have been in- tensified in Uganda (1). With the intensification of these efforts, ac- curate and timely data are needed to monitor impact of the interventions and guide malaria control program planning (2, 3). We present data on trends in malaria burden over four years from six out- patient health facilities located in regions of varying malaria en- demicity in Uganda. Methods The study utilized data from the on-going malaria sentinel sur- veillance program involving six level IV outpatient health facilities: Aduku, Nagongera, Walukuba, Kasambya, Kihihi and Kamwezi. Major malaria control interventions between 2008 and 2010 in sub- counties where these sites are located included Indoor residual spray- ing (IRS) conducted in Aduku; insecticide-treated nets (ITNs) distributed in Nagongera and Kamwezi. There has been no major control intervention(s) in sub-counties where Walukuba, Kasambya and Kihihi are located. Treatment with artemisinin-combination ther- apies have however been deployed nationally. Patient information; demographics, malaria test results and diagnosis are recorded on a standardized patient record. The test positivity rate (TPR) defined as the number of persons testing positive for malaria divided by the total number of persons tested was calculated by year from 2008 to 2011 for two age categories (< 5 years and > 5 years ). Results A total of 560,586 patients were seen, of which 25% were <5 years. Over 325,500 patients were suspected to have malaria, with the pro- portion of these having a confirmatory test done increasing from 62% in 2008 to 98% in 2011. Between 2008 and 2011, the proportion of the <5 years testing positive for malaria significantly decreased from 66% to 34% in Aduku, from 61% to 41% in Nagongera, and from 54% to 24% in Kamwezi. However, significant increases were seen in Kasambya and Kihihi from 41% to 51% and from 28% to 44% re- spectively. The TPR at Walukuba remained stable (41% to 45%). Similar trends were seen in the > 5 years. Conclusions Sentinel site surveillance has been a reliable and timely method/tool for monitoring trends in malaria morbidity thereby in- forming and guiding the Uganda malaria control program. Keywords Surveillance; Malaria; Trends Acknowledgments Acknowledgements to NMCP Team/MOH, CDC/PMI, UMSP Team, Health Facility Staff. References 1) Yeka A, Gasasira A, Mpimbaza A, Achan J, et al. Malaria in Uganda: challenges to control on the long road to elimination: I. Epidemiology and current control efforts. Acta Trop. 2012 Mar;121(3):184-95. Epub 2011 Mar 21 2) Breman JG, Holloway CN. Malaria surveillance counts. Am J Trop Med Hyg 2007;77:36-47 3) Bryce J, Roungou JB, Nguyen-Dinh P, Naimoli JF and Breman JG. Evaluation of national malaria control programmes in Africa. Bull World Health Organ 1994;72:371-81 *Ruth K. Nassali E-mail: ruth.nassali@yahoo.com Online Journal of Public Health Informatics * ISSN 1947-2579 * http://ojphi.org * 5(1):e81, 2013