Layout 1 ISDS Annual Conference Proceedings 2012. This is an Open Access article distributed under the terms of the Creative Commons Attribution- Noncommercial 3.0 Unported License (http://creativecommons.org/licenses/by-nc/3.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ISDS 2012 Conference Abstracts Case Based Surveillance for Measles in Lagos, South Western Nigeria, September 2011 Olawunmi O. Adeoye*1, Abimbola Aman-Oloniyo2, Patrick Nguku1, Abiola Oduneye2 and Modupe Dawodu2 1Nigeria Field Epidemiology and Laboratory Training Programme, Abuja, Nigeria; 2Lagos State Ministry of Health, Alausa, Ikeja, Lagos, Nigeria Objective The objective of this study was to describe the performance of the measles surveillance in Lagos, characterize the epidemiologic pat- tern of measles infection and determine the measles vaccine efficacy. Introduction Measles is a vaccine preventable disease that has been success- fully eliminated in some parts of the world. It causes high morbidity and mortality with the potential of large outbreaks. About a third of reported measles cases involve one or more complications including diarrhea, pneumonia, otitis media, blindness, post infections en- cephalitis and subacute sclerosing panencephalitis. It is however, one of the leading causes of childhood morbidity and mortality in Nige- ria despite availability of safe and effective vaccines Methods We obtained the measles surveillance data for all the 20 Local Governments Areas (LGAs) in Lagos and reviewed all the measles case based investigation forms between the period 1st January to 31st December 2010.The WHO Recommended Surveillance Standards for Measles was used. Data was analyzed using EPI INFO version 3.5.3. Results Of the 615 suspected measles cases, 63(10.2%) were laboratory confirmed (measles IGM+) and 3(0.5%) clinically confirmed. Cases investigated within 48 hours was 222 (36%) (target ! 80%), 510 (83%) had adequate blood sample collected (target ! 80%) and 595 (97%) of sample results were received from the lab within 7 days (target ! 80%). The surveillance system sensitivity was 6.5/100,000 (target >2/100,000) with a predictive value positive of 10.73%. The overall attack rate was 0.73/100,000 population with 1 mortality (case fatality rate 1.5%). The Under 1 year attack rate (8.33/100,000) was higher than the 1- 4 years attack rate (3.48/100,000) (p= 0.01). Those vaccinated with at least 1 dose of measles vaccine had a 3 times lower risk of measles infection than the unvaccinated. The proportion of unvaccinated cases was 36%. The measles vaccine efficacy was 60%. Conclusions The quality of surveillance need to be strengthened by improving the time lapse between notification and investigation of suspected cases. Measles is still a significant cause of morbidity particularly among the under 1 year age group.The proportion of unvaccinated cases is also high, suggesting a low vaccine coverage among sus- ceptibles. Prompt investigation of cases, good vaccine coverage and high vaccine efficacy are all vital in eliminating measles from Nigeria. Morbidity and Mortality rates No of Reported Measles Cases in Lagos, South Western Nigeria by LGA with onset date from 1st January - 31st December 2010 Legend Keywords Surveillance; Measles; Case based; Lagos Acknowledgments Lagos State Ministry of Health, Alausa, Ikeja, Lagos. Central Public Health Laboratory, Yaba, Lagos. World Health Organisation, Lagos Office, Ikoyi, Lagos. References Kohlhagen JK et al. 2011. Meeting Measles Elimination Indicators: Sur- veillance Performance in a Regional Area of Australia. Western Pa- cific Surveillance and Response Journal,2011,2(3). WHO.2001. Modules on Best Practisesfor Measles Surveillance. Avail- able at www.who.int/vaccines-document. (Accessed September 2011). WHO.2003.Recommended Standards for Surveillance of Selected Vac- cine Preventable Diseases.Available at www.who.int/vaccines-docu- ment. (Accessed September 2011). *Olawunmi O. Adeoye E-mail: wunmiolat@yahoo.com Online Journal of Public Health Informatics * ISSN 1947-2579 * http://ojphi.org * 5(1):e151, 2013