2014.ISDS.Abstracts.Final.pdf ISDS Annual Conference Proceedings 2014. This is an Open Access article distributed under the terms of the Creative Commons Attribution- Noncommercial 3.0 Unported License (http://creativecommons.org/licenses/by-nc/3.0/), permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ISDS 2014 Conference Abstracts Google Flu Trends: Spatial Correlation with Influenza Emergency Department Visits Joseph Klembczyk*1, Mehdi Jalalpour2, Scott Levin1, Raynard Washington3, Jesse M. Pines4, Richard Rothman1 and Andrea Dugas1 1School of Medicine, Johns Hopkins University, Baltimore, MD, USA; 2Cleveland State University, Cleveland, OH, USA; 3AHRQ, Rockville, MD, USA; 4George Washington University, Washington, DC, USA Objective To test if Google Flu Trends (GFT) is predictive of the volume of influenza and pneumonia emergency department (ED) visits across multiple United States cities. Introduction GFT is a surveillance tool that gathers data on local internet searches to estimate the emergence of influenza-like illness in a given geographic location in real time.3 Previously, GFT has been proven to strongly correlate with influenza incidence at the national and regional level.2,3 GFT has shown promise as an easily accessed tool to enhance influenza surveillance and forecasting; however, further geographic validation of city-level data is needed. 1,2,6 Methods Using Healthcare Cost and Utilization Project (HCUP) data, we collected weekly counts of ED visits for all patients with ICD-9 codes for pneumonia or influenza from 2005-2011 at 19 different cities geographically spread throughout the US.5 Corresponding GFT data for cities and associated states were collected.4 We then evaluated the correlation between GFT and the volume of pneumonia and influenza-related ED visits in each city. Results Correlation coefficients between city-level GFT and ED visits for pneumonia and influenza from 19 different cities range from 0.67 to 0.93 with a median of 0.84. Coefficients are shown geographically in Figure 1. Conclusions We demonstrate a strong correlation between city-level GFT and ED visits for pneumonia and influenza across numerous US cities. Establishing broad geographic generalizability of city-level GFT is key to understanding its capabilities and further integration into other surveillance or forecasting models. Figure 1: Geographic representation of 19 cities and their respective correlation coefficients for city-level GFT and influenza and pneumonia-related ED visits. Keywords Google Flu Trends; data science; big data; influenza; surveillance Acknowledgments This work was done in collaboration with the Agency for Healthcare Research and Quality (AHRQ). Its contents are solely the responsibility of the authors and do not necessarily represent the official views of AHRQ. References 1. Dugas, A. F., Jalalpour, M., Gel, Y., Levin, S., Torcaso, F., Igusa, T., et al. (2013). Influenza forecasting with google flu trends. PloS One, 8(2), e56176. 2. Dugas, A. F., Hsieh, Y. H., Levin, S. R., Pines, J. M., Mareiniss, D. P., Mohareb, A., et al. (2012). Google flu trends: Correlation with emergency department influenza rates and crowding metrics. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 54(4), 463-469. 3. Ginsberg, J., Mohebbi, M. H., Patel, R. S., Brammer, L., Smolinski, M. S., & Brilliant, L. (2008). Detecting influenza epidemics using search engine query data. Nature, 457(7232), 1012-1014. 4. Google. Google Flu Trends. Available at: http://www.google.org/ flutrends. Accessed 15 June 2014. 5. HCUP Nationwide Emergency Department Sample (NEDS). Healthcare Cost and Utilization Project (HCUP). 2005-2010. Agency for Healthcare Research and Quality, Rockville, MD. www.hcup-us. ahrq.gov/nedsoverview.jsp 6. Pervaiz, F., Pervaiz, M., Abdur Rehman, N., & Saif, U. (2012). FluBreaks: Early epidemic detection from google flu trends. Journal of Medical Internet Research, 14(5), e125. *Joseph Klembczyk E-mail: jklembc1@jhmi.edu Online Journal of Public Health Informatics * ISSN 1947-2579 * http://ojphi.org * (1):e87, 201