# bib

id: cord-259969-q65k590s
author: Kösters, Katrin
title: Cutaneous Vasculitis in a Patient With COVID-19
date: 2020-10-05
extension: .txt
mime: text/plain
words: 829
sentence: 47
flesch: 40
cache: cache/cord-259969-q65k590s.txt
txt: txt/cord-259969-q65k590s.txt
summary:
  However, other groups have described skin manifestations in up to 20% of COVID patients [4, 5] . However, our case demonstrates a small/medium-sized vessel vasculitis with involvement of mucous membranes as the cause of skin manifestations in a patient with COVID-19 that appeared late in the disease.


id: cord-002631-e6rc8mvu
author: Piantadosi, Anne
date: 2017-07-28
extension: .txt
mime: text/plain
words: 1452
sentence: 62
flesch: 31
cache: cache/cord-002631-e6rc8mvu.txt
txt: txt/cord-002631-e6rc8mvu.txt
title:
  Metagenomic Sequencing of an Echovirus 30 Genome From Cerebrospinal Fluid of a Patient With Aseptic Meningitis and Orchitis

summary:
  In this study, we describe the case of a young man with orchitis and aseptic meningitis who was diagnosed with enterovirus infection. In this study, we describe the case of a young man with orchitis and aseptic meningitis who was diagnosed with enterovirus infection.


id: cord-311082-sspcz9t6
author: Chen, Shi
date: 2020-08-07
extension: .txt
mime: text/plain
words: 1528
sentence: 62
flesch: 31
cache: cache/cord-311082-sspcz9t6.txt
txt: txt/cord-311082-sspcz9t6.txt
title:
  Four Challenges Associated With Current Mathematical Modeling Paradigm of Infectious Diseases and Call for a Shift

summary:
  SEIR models are mechanistic models developed almost a century ago [3] . Second, SEIR models are formulated at the population level.


id: cord-032268-oj94e8wo
author: Kaeuffer, Charlotte
date: 2020-09-01
extension: .txt
mime: text/plain
words: 1628
sentence: 71
flesch: 46
cache: cache/cord-032268-oj94e8wo.txt
txt: txt/cord-032268-oj94e8wo.txt
title:
  The BAS²IC score: a useful tool to identify patients at high risk of early progression to severe COVID-19

summary:
  Rapid identification of patients at a high risk of developing severe COVID-19 appeared to be crucial to help clinicians closely monitor such patients and for triage. On the contrary, those with score >14 were considered to have a high risk, requiring rapid implementation of appropriate measures, such as hospitalization and consideration of specific therapeutics (e.g. dexamethasone, remdesivir)


id: cord-270703-c8mv2eve
author: Christensen, Paul A
date: 2018-11-30
extension: .txt
mime: text/plain
words: 1680
sentence: 80
flesch: 43
cache: cache/cord-270703-c8mv2eve.txt
txt: txt/cord-270703-c8mv2eve.txt
title:
  Real-time Communication With Health Care Providers Through an Online Respiratory Pathogen Laboratory Report

summary:
  In addition, clinical laboratories should routinely monitor local influenza data to determine if epidemics are occurring, if continued testing is necessary, or if patients can be treated based on positive symptoms alone [2, 3] . Open Forum Infect Dis DOI: 10.1093/ofid/ofy322 sha: doc_id: 270703 cord_uid: c8mv2eve We implemented a real-time report to distribute respiratory pathogen data for our 8-hospital system to anyone with an Internet connection and a web browser.


id: cord-288044-ver1nrsz
author: Sierra, Beatriz
date: 2020-09-03
extension: .txt
mime: text/plain
words: 1938
sentence: 70
flesch: 40
cache: cache/cord-288044-ver1nrsz.txt
txt: txt/cord-288044-ver1nrsz.txt
title:
  Association of early nasopharyngeal immune markers with COVID-19 clinical outcome: predictive value of CCL2/MCP-1

summary:
  We hypothesized that the activity of this set of cytokines/chemokines could trigger/suppress the severe outcome of infection, resulting in confirmed COVID-19 patients with asymptomatic infections or different clinical evolutions. Dyspnea has been reported to be more frequent in COVID-19 severe cases, and indeed, in some studies, it was included as a marker of severe disease (15, 16) .


id: cord-252305-rstxyofq
author: Tyan, Kevin
date: 2020-08-31
extension: .txt
mime: text/plain
words: 2063
sentence: 79
flesch: 36
cache: cache/cord-252305-rstxyofq.txt
txt: txt/cord-252305-rstxyofq.txt
title:
  Considerations for the Selection and Use of Disinfectants Against SARS-CoV-2 in a Healthcare Setting

summary:
  However, limited guidance exists on effective surface disinfectants or best practices for their use against SARS-CoV-2. Limited guidance exists on effective surface disinfectants or best practices for disinfectant use against SARS-CoV-2.


id: cord-303091-jky6jlrl
author: Cellai, Michele
title: Characterization of prolonged COVID-19 symptoms in an outpatient telemedicine clinic
date: 2020-09-12
extension: .txt
mime: text/plain
words: 1951
sentence: 81
flesch: 51
cache: cache/cord-303091-jky6jlrl.txt
txt: txt/cord-303091-jky6jlrl.txt
summary:
  Due to the presence of persistent symptoms, 16 (61.5%) of patients delayed return to work at least five weeks from symptom onset, 17 (65.3%) delayed return to activity. jky6jlrl We identified patients with coronavirus disease 2019 (COVID-19) in a telemedicine clinic who requested ongoing follow-up calls 6 weeks after symptom onset.


id: cord-261619-31jk1vh6
author: Lindholm, David A
title: Outcomes of Coronavirus Disease 2019 Drive-Through Screening at an Academic Military Medical Center
date: 2020-07-17
extension: .txt
mime: text/plain
words: 2181
sentence: 96
flesch: 44
cache: cache/cord-261619-31jk1vh6.txt
txt: txt/cord-261619-31jk1vh6.txt
summary:
  Although our testing protocol focused on symptomatic patients, a universal-testing program in South Korea found that 2.6% of asymptomatic patients without a history of close contact tested positive [11] . Open Forum Infect Dis DOI: 10.1093/ofid/ofaa306 sha: doc_id: 261619 cord_uid: 31jk1vh6 Drive-through coronavirus disease 2019 screening can evaluate large numbers of patients while reducing healthcare exposures and personal protective equipment use.


id: cord-305512-p5qchjva
author: Alghamdi, Abdulaziz
date: 2019-09-30
extension: .txt
mime: text/plain
words: 2605
sentence: 87
flesch: 39
cache: cache/cord-305512-p5qchjva.txt
txt: txt/cord-305512-p5qchjva.txt
title:
  Molecular Evidence of Influenza A Virus Circulation in African Dromedary Camels Imported to Saudi Arabia, 2017–2018

summary:
  Several outbreaks of severe respiratory diseases in bactrian camels have occurred between 1978 and 1988 in Mongolia and were suspected to be due to influenza viruses [7] . Although the existence of influenza viruses in dromedary camels has not been investigated properly, previous studies provided limited serological evidence of circulation of all influenza types (A, B, C, and D) among dromedaries in several African countries [9] [10] [11] .


id: cord-268975-xzdh8yum
author: Huang, Jing
title: Public behavior change, perceptions, depression, and anxiety in relation to the COVID-19 outbreak
date: 2020-07-03
extension: .txt
mime: text/plain
words: 2600
sentence: 117
flesch: 50
cache: cache/cord-268975-xzdh8yum.txt
txt: txt/cord-268975-xzdh8yum.txt
summary:
  The prevalence of public behaviors, perceptions, depression, and anxiety changed less than 1% or marginally 1% after weighting procedure, therefore the unweighted data were used for analysis in this study. Public protective behaviors and perception play crucial roles in controlling the spread of illness and psychological status.


id: cord-310872-2z1wnj63
author: Spellberg, Brad
title: Alignment With Market Forces: The “Re-Whithering” of Infectious Diseases
date: 2020-06-20
extension: .txt
mime: text/plain
words: 2903
sentence: 142
flesch: 49
cache: cache/cord-310872-2z1wnj63.txt
txt: txt/cord-310872-2z1wnj63.txt
summary:
  Indeed, ID practitioners are 1 of only 2 subspecialties remunerated below general internists in the United States [8] , raising the obvious questionwhy should top talent choose to spend 2 or more additional years in training to end up making less money? First, ID practitioners have unique expertise in the diagnosis and treatment of infections, which can lead to less antimicrobial resistance and superinfections, better outcomes, and lower cost for patients and health systems.


id: cord-310807-p5cb6idp
author: Kanwar, Anubhav
title: Human Coronavirus-HKU1 Infection Among Adults in Cleveland, Ohio
date: 2017-03-25
extension: .txt
mime: text/plain
words: 2957
sentence: 157
flesch: 44
cache: cache/cord-310807-p5cb6idp.txt
txt: txt/cord-310807-p5cb6idp.txt
summary:
  A systematic review and meta-analysis of randomized controlled trials Etiology and clinical characterization of respiratory virus infections in adult patients attending an emergency department in Beijing Detection of the new human coronavirus HKU1: a report of 6 cases Human coronaviruses are uncommon in patients with gastrointestinal illness Prevalence of gastrointestinal symptoms in patients with influenza, clinical significance, and pathophysiology of human influenza viruses in faecal samples: what do we know Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection Viral shedding and antibody response in 37 patients with middle east respiratory syndrome coronavirus infection Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method Use of a novel virus detection assay to identify coronavirus HKU1 in the lungs of a hematopoietic stem cell transplant recipient with fatal pneumonia A prospective hospital-based study of the clinical impact of non-severe acute respiratory syndrome (Non-SARS)-related human coronavirus infection Antibiotic discontinuation rates associated with positive respiratory viral panel and low procalcitonin results in proven or suspected respiratory infections Impact of antibacterials on subsequent resistance and clinical outcomes in adult patients with viral pneumonia: an opportunity for stewardship Access to a polymerase chain reaction assay method targeting 13 respiratory viruses can reduce antibiotics: a randomised, controlled trial The role of infections and coinfections with newly identified and emerging respiratory viruses in children Rate and influence of respiratory virus co-infection on pandemic (H1N1) influenza disease Detection of four human coronaviruses in respiratory infections in children: a one-year study in Colorado Coronavirus-HKU1 accounted for 1.6% of adult respiratory infections and should be considered in differential diagnosis of severe respiratory illnesses among adults.


id: cord-314517-n1yj2zdy
author: Huang, Dayong
date: 2020-08-31
extension: .txt
mime: text/plain
words: 2947
sentence: 130
flesch: 47
cache: cache/cord-314517-n1yj2zdy.txt
txt: txt/cord-314517-n1yj2zdy.txt
title:
  Social media survey and web posting assessment of the COVID-19 response in China: Health worker attitudes towards preparedness and personal protective equipment shortages

summary:
  While we did not indicated exclusion criteria in the recruitment poster (supplemental Fig 1) , we specified our research aims regarding self-perception of health worker preparedness. We conducted a cross-sectional survey from February 24-28, 2020 to assess COVID-19 preparedness among health workers.


id: cord-321000-3jd2gn73
author: Karra, Nour
date: 2020-08-13
extension: .txt
mime: text/plain
words: 3082
sentence: 192
flesch: 34
cache: cache/cord-321000-3jd2gn73.txt
txt: txt/cord-321000-3jd2gn73.txt
title:
  A Case of Hemophagocytic Lymphohistiocytosis Associated With Mediterranean Spotted Fever in a Healthy 29-Year-Old Female

summary:
  Second, many diagnostic criteria are nonspecific (fever, cytopenias, hypofibrinogenemia) and may be encountered Contrarily, HLH patients frequently exhibit findings other than those included in the diagnostic criteria (hypoalbuminemia, elevated liver enzymes, coagulopathy). An increasing number of acquired HLH cases have been reported in recent years [3] .


id: cord-320511-qnxj7d9l
author: Hueston, Linda
title: The antibody response to SARS-CoV-2 infection
date: 2020-08-27
extension: .txt
mime: text/plain
words: 3122
sentence: 115
flesch: 37
cache: cache/cord-320511-qnxj7d9l.txt
txt: txt/cord-320511-qnxj7d9l.txt
summary:
  False Positive Results with BD SARS-CoV-2 Reagents for the BD Max System -Letter to Clinical Laboratory Staff and Health Care Providers Public Health Laboratory Network Statement on Nucleic Acid Test False Positive Results for SARS-CoV-2 Interpret with caution: An evaluation of the commercial AusDiagnostics versus in-house developed assays for the detection of SARS-CoV-2 virus False-positive reverse transcriptase polymerase chain reaction screening for SARS-CoV-2 in the setting of urgent head and neck surgery and otolaryngologic emergencies during the pandemic: Clinical implications Real-time RT-PCR in COVID-19 detection: issues affecting the results IgA-Ab response to spike glycoprotein of SARS-CoV-2 in patients with COVID-19: A longitudinal study Persistence of Antibodies against Middle East Respiratory Syndrome Coronavirus Duration of antibody responses after severe acute respiratory syndrome Longitudinal profile of antibodies against SARS-coronavirus in SARS patients and their clinical significance Viral Shedding and Antibody Response in 37 Patients With Middle East Respiratory Syndrome Coronavirus Infection Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans MERS-CoV Antibody Responses 1 Year after Symptom Onset, South Korea A comparison study of SARS-CoV-2 IgG antibody between male and female COVID-19 patients: a possible reason underlying different outcome between sex Profile of specific antibodies to SARS-CoV-2: The first report Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients Virological assessment of hospitalized patients with COVID-2019 Long-term coexistence of SARS-CoV-2 with antibody response in COVID-19 patients Rapid point-of-care testing for SARS-CoV-2 in a community screening setting shows low sensitivity The magnitude and persistence of antibody responses are critical for assessing the duration of immunity.


id: cord-282862-kve6fa49
author: Pastick, Katelyn A
date: 2020-08-13
extension: .txt
mime: text/plain
words: 3317
sentence: 138
flesch: 39
cache: cache/cord-282862-kve6fa49.txt
txt: txt/cord-282862-kve6fa49.txt
title:
  A Systematic Review of Treatment and Outcomes of Pregnant Women with COVID-19 – A Call for Clinical Trials

summary:
  We then evaluated the proportion of COVID-19 clinical trials (from Clinicaltrials.gov) excluding pregnant or breastfeeding persons (both through June 29(th), 2020). A second search was conducted to identify COVID-19 clinical trials as of June 29th, 2020 that reported pregnancy/breastfeeding as an exclusion criterion.


id: cord-260257-phmd0u6d
author: Siegler, Aaron J
date: 2020-06-30
extension: .txt
mime: text/plain
words: 3715
sentence: 148
flesch: 44
cache: cache/cord-260257-phmd0u6d.txt
txt: txt/cord-260257-phmd0u6d.txt
title:
  Willingness to seek laboratory testing for SARS-CoV-2 with home, drive-through, and clinic-based specimen collection locations

summary:
  Differences in mean willingness scores across testing modalities were all significant (p<.001), with very small effect size for home saliva testing compared to home throat swab testing (d=0.12), medium effect size for home saliva testing compared to drive-through testing (d=0.55), and large effect size for home saliva testing compared to clinic-based testing (d=0.81). There was a hierarchy of willingness to test for SARS-CoV-2 that was decreased as the required degree of contact with healthcare systems increased: home testing was most preferred, followed by drive-through testing, and then by laboratory or clinicbased testing.


id: cord-252751-prock3co
author: Kalligeros, Markos
date: 2020-08-06
extension: .txt
mime: text/plain
words: 3964
sentence: 155
flesch: 46
cache: cache/cord-252751-prock3co.txt
txt: txt/cord-252751-prock3co.txt
title:
  Remdesivir Use Compared to Supportive Care in Hospitalized Patients with Severe COVID-19: A Single-Center Experience

summary:
  For the purposes of the present study we created a control group consisting of hospitalized patients with PCR confirmed COVID-19 who did not receive remdesivir. The US Food and Drug Administration issued an Emergency Use Authorization for remdesivir use in patients with severe COVID-19.


id: cord-258113-mnou31j3
author: Wang, Yaping
date: 2020-05-19
extension: .txt
mime: text/plain
words: 3900
sentence: 187
flesch: 52
cache: cache/cord-258113-mnou31j3.txt
txt: txt/cord-258113-mnou31j3.txt
title:
  Clinical Characteristics of Patients Infected With the Novel 2019 Coronavirus (SARS-Cov-2) in Guangzhou, China

summary:
  Imported group patients were those who had been to Wuhan within 14 days or who were residents of Wuhan before admission, and the local group included patients who had not left Guangdong during the past month. So it is important to evaluate ALB levels dynamically in these patients. RT-PCR analysis of respiratory or fecal samples, together with serological testing, can confirm the diagnosis of SARS-CoV infection in most SARS patients.


id: cord-256195-1hmzgwrw
author: Izzy, Saef
date: 2020-09-01
extension: .txt
mime: text/plain
words: 4110
sentence: 156
flesch: 37
cache: cache/cord-256195-1hmzgwrw.txt
txt: txt/cord-256195-1hmzgwrw.txt
title:
  Characteristics and outcomes of Latinx patients with COVID-19 in comparison to other ethnic and racial groups

summary:
  15, 26 Our firsthand clinical experience with COVID-19 patients indicate that in addition to African American patients, a higher percentage of COVID-19 Latinx patients required hospitalization and critical care admission. 10, 11 Hypertension, heart disease, obesity, and diabetes are common comorbidities associated with hospitalization in COVID-19 patients.


id: cord-001654-o2zfilcl
author: Laidler, Matthew R.
date: 2015-03-04
extension: .txt
mime: text/plain
words: 4010
sentence: 161
flesch: 36
cache: cache/cord-001654-o2zfilcl.txt
txt: txt/cord-001654-o2zfilcl.txt
title:
  Statin Treatment and Mortality: Propensity Score-Matched Analyses of 2007–2008 and 2009–2010 Laboratory-Confirmed Influenza Hospitalizations

summary:
  Two studies evaluating statin use during multiple influenza seasons in the decade before the 2009 pandemic found a protective effect on influenza mortality, although 1 of the studies found only a modest (10% reduction in deaths from pneumonia) Nonetheless, we also found a protective effect of statins on death among laboratoryconfirmed influenza patients hospitalized during the 2007-2008 season.


id: cord-003565-14g33n7j
author: Frey, Sharon E
date: 2019-03-01
extension: .txt
mime: text/plain
words: 4174
sentence: 158
flesch: 45
cache: cache/cord-003565-14g33n7j.txt
txt: txt/cord-003565-14g33n7j.txt
title:
  Safety and Immunogenicity of MF59-Adjuvanted Cell Culture–Derived A/H5N1 Subunit Influenza Virus Vaccine: Dose-Finding Clinical Trials in Adults and the Elderly

summary:
  The main exclusion criteria were presence of serious chronic or progressive disease, pregnancy or breastfeeding, prior receipt of any H5N1 vaccine, receipt of any other influenza vaccines within 60 days before enrollment, body temperature ≥38.0°C and/or any acute illness within 3 days of receiving study vaccines, and a body mass index ≥35 kg/m 2 (see ClinicalTrials.gov for all exclusion criteria). The immunogenicity analyses were performed on full analysis set (FAS) data, which included all subjects who received at least 1 dose of study vaccine and provided at least 1 serum sample at both prevaccination and postvaccination time points.


id: cord-010773-z2eogm18
author: Vora, Surabhi B
date: 2020-04-09
extension: .txt
mime: text/plain
words: 4164
sentence: 198
flesch: 49
cache: cache/cord-010773-z2eogm18.txt
txt: txt/cord-010773-z2eogm18.txt
title:
  Infectious Complications Following CD19 Chimeric Antigen Receptor T-cell Therapy for Children, Adolescents, and Young Adults

summary:
  In a Cox proportional hazards model of the impact of preand post-CTI variables on time to first infection, prior HCT (hazard ratio [HR], 2.15; 95% CI, 0.98-4.73) and post-CTI hypogammaglobulinemia (HR, 2.41; 95% CI, 1.02-5.69) were associated with increased infection risk in the first 28 days in the adjusted model (Table 4 ). This analysis also confirmed the decrease in infection risk with cyclophosphamide and fludarabine lymphodepletion.


id: cord-303935-qdehf6rb
author: Yun, Heather C.
date: 2015-09-01
extension: .txt
mime: text/plain
words: 4254
sentence: 166
flesch: 39
cache: cache/cord-303935-qdehf6rb.txt
txt: txt/cord-303935-qdehf6rb.txt
title:
  Changes in Clinical Presentation and Epidemiology of Respiratory Pathogens Associated With Acute Respiratory Illness in Military Trainees After Reintroduction of Adenovirus Vaccine

summary:
  Because respiratory illness remains a leading cause of presentation for care among military trainees, understanding of trends in clinical presentation and emerging, non-Ad respiratory pathogens in the post-VI era requires evaluation. Ill or injured trainees present for care at an outpatient medical clinic; those with respiratory illness and fever are then cohorted until well enough to return to training.


id: cord-296890-08kqtw8s
author: Toh, Teck-Hock
date: 2019-02-13
extension: .txt
mime: text/plain
words: 4332
sentence: 170
flesch: 46
cache: cache/cord-296890-08kqtw8s.txt
txt: txt/cord-296890-08kqtw8s.txt
title:
  High Prevalence of Viral Infections Among Hospitalized Pneumonia Patients in Equatorial Sarawak, Malaysia

summary:
  T One pediatric patient specimen destroyed, assay results out of n = 599. Surveillance for emerging respiratory viruses Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance Addressing the public health burden of respiratory viruses: the Battle against Respiratory Viruses (BRaVe) initiative Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory tract infections in 195 countries: a systematic analysis for the Global Burden of Disease Study Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis Global burden of childhood pneumonia and diarrhoea Clinical and economic burden of community-acquired pneumonia amongst adults in the Asia-Pacific region The bacterial aetiology of adult community-acquired pneumonia in Asia: a systematic review Assessing the burden of pneumonia using administrative data from Malaysia, Indonesia, and the Philippines Epidemiology and seasonality of respiratory viral infections in hospitalized children in Kuala Lumpur, Malaysia: a retrospective study of 27 years Surveillance for respiratory syncytial virus and parainfluenza virus among patients hospitalized with pneumonia in Sarawak Community-acquired pneumonia requiring hospitalization among U.S. children Community-acquired pneumonia requiring hospitalization among U.S. adults Humidity as a non-pharmaceutical intervention for influenza A Absolute humidity modulates influenza survival, transmission, and seasonality Respiratory syncytial virus-a comprehensive review Pneumonia: a global cause without champions Respiratory syncytial virus subtype A was detected in the third patient's NP swab.


id: cord-267023-w5ig7mrl
author: Nori, Priya
date: 2017-07-20
extension: .txt
mime: text/plain
words: 4348
sentence: 197
flesch: 31
cache: cache/cord-267023-w5ig7mrl.txt
txt: txt/cord-267023-w5ig7mrl.txt
title:
  Developing Interactive Antimicrobial Stewardship and Infection Prevention Curricula for Diverse Learners: A Tailored Approach

summary:
  Commentary: IDSA guidelines for improving the teaching of preclinical medical microbiology and infectious diseases Faculty and resident physicians' attitudes, perceptions, and knowledge about antimicrobial use and resistance Medical students' perceptions and knowledge about antimicrobial stewardship: how are we educating our future prescribers? Implementing an Antibiotic Stewardship Program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Hand-hygiene behaviour, attitudes and beliefs in first year clinical medical students Now please wash your hands': the handwashing behaviour of final MBBS candidates Usage of ultraviolet test method for monitoring the efficacy of surgical hand rub technique among medical students Critical gaps in knowledge of the epidemiology and pathophysiology of healthcare-associated infections Hand hygiene in medical students: performance, education and knowledge Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship New societal approaches to empowering antibiotic stewardship CMS Issues Proposed Rule that Prohibits Discrimination, Reduces Hospital-Acquired Conditions, and Promotes Antibiotic Stewardship in Hospitals Health care provider education as a tool to enhance antibiotic stewardship practices Is there an app for that? Likewise, studies in medical student education reveal (1) poor knowledge and practices of infection prevention and (2) gaps in understanding of healthcare-associated infections (HAIs) due to lack of emphasis and suboptimal practices among supervising physicians [5] [6] [7] [8] .


id: cord-268662-mw8ec7u2
author: Salton, Francesco
title: Prolonged low-dose methylprednisolone in patients with severe COVID-19 pneumonia
date: 2020-09-12
extension: .txt
mime: text/plain
words: 4410
sentence: 166
flesch: 40
cache: cache/cord-268662-mw8ec7u2.txt
txt: txt/cord-268662-mw8ec7u2.txt
summary:
  No tracheostomy was necessary in MP patients vs. 12 controls (OR 0.04, 95% CI 0.002 to 0.64, p-value <0.001). [1] COVID-19 patients with ARF necessitate weeks of mechanical ventilation (MV) and have an unacceptably high mortality rate.


id: cord-274943-fn3m14cn
author: Philpott, Erin K
title: Febrile Rhinovirus Illness During Pregnancy Is Associated With Low Birth Weight in Nepal
date: 2017-04-06
extension: .txt
mime: text/plain
words: 4858
sentence: 194
flesch: 42
cache: cache/cord-274943-fn3m14cn.txt
txt: txt/cord-274943-fn3m14cn.txt
summary:
  Multivariate regression analysis evaluated the association between febrile HRV respiratory illness and adverse birth outcomes. The frequencies of each adverse outcome were compared between infants born to mothers with febrile HRV respiratory illness during pregnancy and those without febrile HRV respiratory illness during pregnancy.


id: cord-256130-zhlvvuj4
author: Nordén, Rickard
date: 2018-03-06
extension: .txt
mime: text/plain
words: 4856
sentence: 187
flesch: 42
cache: cache/cord-256130-zhlvvuj4.txt
txt: txt/cord-256130-zhlvvuj4.txt
title:
  Quantification of Torque Teno Virus and Epstein-Barr Virus Is of Limited Value for Predicting the Net State of Immunosuppression After Lung Transplantation

summary:
  When Tacrolimus was the main immunosuppressive treatment, TTV DNA levels were significantly elevated 6–24 months after transplantation as compared with Cyclosporine treatment. To compare results regarding TTV levels between different transplantation centers, it is vital to reliably quantify the concentrations of TTV-DNA in a standardized manner.


id: cord-322524-bq9ok8h1
author: Belongia, Edward A
date: 2018-11-27
extension: .txt
mime: text/plain
words: 5191
sentence: 215
flesch: 39
cache: cache/cord-322524-bq9ok8h1.txt
txt: txt/cord-322524-bq9ok8h1.txt
title:
  Clinical Features, Severity, and Incidence of RSV Illness During 12 Consecutive Seasons in a Community Cohort of Adults ≥60 Years Old

summary:
  Additional studies are needed in diverse populations to estimate the burden of adult RSV illness and the potential impact of future licensed vaccines. Samples collected from the 2004-2005 through 2009-2010 seasons were previously tested using the GenMark multiplex assay in a separate study of RSV illness in adults ≥50 years of age [19] .


id: cord-327609-no58ucyq
author: Murkey, Jamie A.
date: 2017-06-13
extension: .txt
mime: text/plain
words: 1954
sentence: 79
flesch: 30
cache: cache/cord-327609-no58ucyq.txt
txt: txt/cord-327609-no58ucyq.txt
title:
  Hepatitis E Virus–Associated Meningoencephalitis in a Lung Transplant Recipient Diagnosed by Clinical Metagenomic Sequencing

summary:
  Validation of metagenomic next-generation sequencing tests for universal pathogen detection Neurobrucellosis: unexpected answer from metagenomic next-generation sequencing Hepatitis E virus reinfections in solid-organ-transplant recipients can evolve into chronic infections Hepatitis E virus infection among solid organ transplant recipients, the Netherlands Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants Hepatitis E virus and neurologic disorders Evidence of hepatitis E virus breaking through the blood-brain barrier and replicating in the central nervous system A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples Treatment of HEV infection in patients with a solid-organ transplant and chronic hepatitis Liver transplant from a donor with occult HEV infection induced chronic hepatitis and cirrhosis in the recipient Evidence of hepatitis E virus transmission by renal graft We would like to thank the patient for participating in the PDAID research study. We demonstrate the power of clinical mNGS in elucidating the cause of uncommon and unexpected infections and identify a case of chronic HEV infection most likely transmitted through the transplanted lungs the patient had received 6 years prior.


id: cord-350557-7i7122zi
author: Rawlings, Stephen A
date: 2020-08-07
extension: .txt
mime: text/plain
words: 1756
sentence: 73
flesch: 49
cache: cache/cord-350557-7i7122zi.txt
txt: txt/cord-350557-7i7122zi.txt
title:
  No Evidence of SARS-CoV-2 Seminal Shedding Despite SARS-CoV-2 Persistence in the Upper Respiratory Tract

summary:
  All 6 semen samples were negative for SARS CoV-2 (≤0.03 copies/µL), while SARS-CoV-2 was still detected in all saliva samples (6 participants) and all research nasal swabs (3 participants). Paired saliva and semen samples were collected a mean of 12 days (6-17 days) after the onset of symptoms, and ddPCR was performed to quantify the SARS-CoV-2 level in all samples.


id: cord-350767-6kc4hyzo
author: Beh, Darius L L
title: The Pandemic Academy: Reflections of Infectious Diseases Fellows During COVID-19
date: 2020-06-25
extension: .txt
mime: text/plain
words: 2467
sentence: 106
flesch: 49
cache: cache/cord-350767-6kc4hyzo.txt
txt: txt/cord-350767-6kc4hyzo.txt
summary:
  As we mark 3 months of our fellowship in the COVID-19 era, we reflect on our experiences and the unique impact of this pandemic on ID fellows. Strange as it may be for ID fellows, our specific role during a pandemic of this scale is not well-defined.


id: cord-351022-8y43jhmu
author: Schwartz, Carmela
date: 2020-09-01
extension: .txt
mime: text/plain
words: 2902
sentence: 116
flesch: 50
cache: cache/cord-351022-8y43jhmu.txt
txt: txt/cord-351022-8y43jhmu.txt
title:
  A dynamic response to exposures of healthcare workers to newly diagnosed COVID-19 patients or hospital personnel, in order to minimize cross transmission and need for suspension from work during the outbreak

summary:
  Furthermore, immediate epidemiological investigation and, if needed, early suspension from work of exposed HCWs is needed in order to limit the spread of infection to and between HCWs and patients (7) (8) . Immediate epidemiological investigations of exposed HCWs were initiated, in order to break the chain of cross-transmission between HCWs as well as avoiding transmission from HCWs to patients, thus keeping maximal work force available.


id: cord-334210-lhadzo7o
author: Lepak, Alexander J
date: 2020-08-27
extension: .txt
mime: text/plain
words: 3674
sentence: 150
flesch: 46
cache: cache/cord-334210-lhadzo7o.txt
txt: txt/cord-334210-lhadzo7o.txt
title:
  Utility of Repeat Nasopharyngeal SARS-CoV-2 RT-PCR Testing and Refinement of Diagnostic Stewardship Strategies at a Tertiary Care Academic Center in a low Prevalence Area of the United States

summary:
  Advice on which procedures met criteria was circulated to all providers, but, as with repeat PUI testing, proper test utilization was not actively enforced. The remainder of inpatients tested negative on repeat PUI testing.


id: cord-333459-asem8xjz
author: Mallipattu, S K
date: 2020-09-14
extension: .txt
mime: text/plain
words: 3206
sentence: 120
flesch: 41
cache: cache/cord-333459-asem8xjz.txt
txt: txt/cord-333459-asem8xjz.txt
title:
  Geospatial Distribution and Predictors of Mortality in Hospitalized Patients with COVID-19: A Cohort Study

summary:
  Study patients were predominantly hypertensive (MAP>90mmHg (670, 51%)) The global Coronavirus Disease 2019 (COVID-19) pandemic offers the opportunity to assess how hospitals managed the care of hospitalized patients with varying demographics and clinical presentation.


id: cord-326642-kc85pev4
author: Cohen, Adam L.
date: 2015-09-19
extension: .txt
mime: text/plain
words: 4063
sentence: 153
flesch: 45
cache: cache/cord-326642-kc85pev4.txt
txt: txt/cord-326642-kc85pev4.txt
title:
  Parainfluenza Virus Infection Among Human Immunodeficiency Virus (HIV)-Infected and HIV-Uninfected Children and Adults Hospitalized for Severe Acute Respiratory Illness in South Africa, 2009–2014

summary:
  A preliminary study of pneumonia etiology among hospitalized children in Kenya Severe influenza-associated lower respiratory tract infection in a high HIV-prevalence setting-South Africa Severe lower respiratory tract infections associated with human parainfluenza viruses 1-3 in children infected and non-infected with HIV type 1 An investigation into the prevalence and outcome of patients admitted to a pediatric intensive care unit with viral respiratory tract infections in Cape Town, South Africa Respiratory viral coinfections identified by a 10-plex real-time reverse-transcription polymerase chain reaction assay in patients hospitalized with severe acute respiratory illness-South Africa Epidemiology of severe acute respiratory illness among adults and children aged ≥5 years in a high HIV-prevalence setting Epidemiology of viral-associated acute lower respiratory tract infection among children <5 years of age in a high HIV prevalence setting Evaluation and improvement of real-time PCR assays targeting lytA, ply, and psaA genes for detection of pneumococcal DNA Population-based incidence of severe acute respiratory virus infections among children aged <5 years in rural Bangladesh Viral etiologies of hospitalized acute lower respiratory infection patients in China Hospitalization due to human parainfluenza virus-associated lower respiratory tract illness in rural Thailand Etiology and epidemiology of viral pneumonia among hospitalized children in rural Mozambique: a malaria endemic area with high prevalence of human immunodeficiency virus Incidence and etiology of acute lower respiratory tract infections in hospitalized children younger than 5 years in rural Thailand Interaction between influenza virus and Streptococcus pneumoniae in severe pneumonia Association between respiratory syncytial virus activity and pneumococcal disease in infants: a time series analysis of US hospitalization data Seasonal trends of human parainfluenza viral infections: United States Viral etiology of influenza-like illnesses in Cameroon Progress in the development of human parainfluenza virus vaccines In our second analysis, univariate and multivariable logistic regression was used to determine factors associated with HIV infection among patients with PIV-associated SARI from January 2009 to December 2014 at all SARI sites.


id: cord-279334-j0i9ozsz
author: McCreary, Erin K
title: Coronavirus Disease 2019 Treatment: A Review of Early and Emerging Options
date: 2020-03-23
extension: .txt
mime: text/plain
words: 8289
sentence: 320
flesch: 41
cache: cache/cord-279334-j0i9ozsz.txt
txt: txt/cord-279334-j0i9ozsz.txt
summary:
  The diagnosis and treatment guide of COVID-19 pneumonia caused by new coronavirus infection 7th Edition Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore Case of the index patient who caused tertiary transmission of COVID-19 infection in Korea: the application of lopinavir/ritonavir for the treatment of COVID-19 infected pneumonia monitored by quantitative RT-PCR The course of clinical diagnosis and treatment of a case infected with coronavirus disease 2019 Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 Pharmacokinetics of lopinavir/ritonavir crushed versus whole tablets in children Nitazoxanide, a new drug candidate for the treatment of Middle East respiratory syndrome coronavirus Effect of nitazoxanide in adults and adolescents with acute uncomplicated influenza: a double-blind, randomised, placebo-controlled, phase 2b/3 trial Efficacy and safety of nitazoxanide in addition to standard of care for the treatment of severe acute respiratory illness Tocilizumab for the treatment of chimeric antigen receptor T cell-induced cytokine release syndrome ASTCT consensus grading for cytokine release syndrome and neurologic toxicity associated with immune effector cells Cytokine release syndrome grade as a predictive marker for infections in patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with chimeric antigen receptor T cells FDA approval summary: tocilizumab for treatment of chimeric antigen receptor T cell-induced severe or life-threatening cytokine release syndrome Effective treatment of severe COVID-19 patients with tocilizumab SARS: systematic review of treatment effects Treatment of severe acute respiratory syndrome with glucosteroids: the Guangzhou experience Effects of early corticosteroid treatment on plasma SARS-associated coronavirus RNA concentrations in adult patients The use of corticosteroid as treatment in SARS was associated with adverse outcomes: a retrospective cohort study Corticosteroid therapy for critically ill patients with Middle East respiratory syndrome Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China On the use of corticosteroids for 2019-nCoV pneumonia Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area There are 4 clinical trials currently enrolling patients in the United States (Table 1) .


id: cord-347255-fl9lur4h
author: May, Larissa
date: 2019-11-05
extension: .txt
mime: text/plain
words: 4067
sentence: 139
flesch: 34
cache: cache/cord-347255-fl9lur4h.txt
txt: txt/cord-347255-fl9lur4h.txt
title:
  Rapid Multiplex Testing for Upper Respiratory Pathogens in the Emergency Department: A Randomized Controlled Trial

summary:
  Thus, we conducted a randomized clinical trial of the FilmArray RP vs usual care in ED patients with signs or symptoms of upper respiratory infection or influenza-like illness. We conducted a prospective, patient-oriented, pilot randomized clinical trial of rapid multiplex respiratory pathogen testing (RP test group) vs usual care (usual care or control group) in a level 1 emergency department with limited use of single-organism rapid point-of-care tests at a quaternary referral medical center.


