item: #1 of 40 id: cord-001654-o2zfilcl author: Laidler, Matthew R. title: Statin Treatment and Mortality: Propensity Score-Matched Analyses of 2007–2008 and 2009–2010 Laboratory-Confirmed Influenza Hospitalizations date: 2015-03-04 words: 4010 flesch: 36 summary: Two studies evaluating statin use during multiple influenza seasons in the decade before the 2009 pandemic found a protective effect on influenza mortality, although 1 of the studies found only a modest (10% reduction in deaths from pneumonia) Nonetheless, we also found a protective effect of statins on death among laboratoryconfirmed influenza patients hospitalized during the 2007-2008 season. keywords: chronic; data; disease; influenza; mortality; pandemic; patients; statin; treatment cache: cord-001654-o2zfilcl.txt plain text: cord-001654-o2zfilcl.txt item: #2 of 40 id: cord-002631-e6rc8mvu author: Piantadosi, Anne title: Metagenomic Sequencing of an Echovirus 30 Genome From Cerebrospinal Fluid of a Patient With Aseptic Meningitis and Orchitis date: 2017-07-28 words: 1452 flesch: 31 summary: In this study, we describe the case of a young man with orchitis and aseptic meningitis who was diagnosed with enterovirus infection. In this study, we describe the case of a young man with orchitis and aseptic meningitis who was diagnosed with enterovirus infection. keywords: echovirus; genome; meningitis; orchitis; sequencing cache: cord-002631-e6rc8mvu.txt plain text: cord-002631-e6rc8mvu.txt item: #3 of 40 id: cord-003565-14g33n7j author: Frey, Sharon E title: Safety and Immunogenicity of MF59-Adjuvanted Cell Culture–Derived A/H5N1 Subunit Influenza Virus Vaccine: Dose-Finding Clinical Trials in Adults and the Elderly date: 2019-03-01 words: 4174 flesch: 45 summary: The main exclusion criteria were presence of serious chronic or progressive disease, pregnancy or breastfeeding, prior receipt of any H5N1 vaccine, receipt of any other influenza vaccines within 60 days before enrollment, body temperature ≥38.0°C and/or any acute illness within 3 days of receiving study vaccines, and a body mass index ≥35 kg/m 2 (see ClinicalTrials.gov for all exclusion criteria). The immunogenicity analyses were performed on full analysis set (FAS) data, which included all subjects who received at least 1 dose of study vaccine and provided at least 1 serum sample at both prevaccination and postvaccination time points. keywords: adult; dose; h5n1; half; influenza; study; subjects; vaccine cache: cord-003565-14g33n7j.txt plain text: cord-003565-14g33n7j.txt item: #4 of 40 id: cord-010773-z2eogm18 author: Vora, Surabhi B title: Infectious Complications Following CD19 Chimeric Antigen Receptor T-cell Therapy for Children, Adolescents, and Young Adults date: 2020-04-09 words: 4164 flesch: 49 summary: In a Cox proportional hazards model of the impact of preand post-CTI variables on time to first infection, prior HCT (hazard ratio [HR], 2.15; 95% CI, 0.98-4.73) and post-CTI hypogammaglobulinemia (HR, 2.41; 95% CI, 1.02-5.69) were associated with increased infection risk in the first 28 days in the adjusted model (Table 4 ). This analysis also confirmed the decrease in infection risk with cyclophosphamide and fludarabine lymphodepletion. keywords: car; cell; cti; days; infection; patients; post cache: cord-010773-z2eogm18.txt plain text: cord-010773-z2eogm18.txt item: #5 of 40 id: cord-032268-oj94e8wo author: Kaeuffer, Charlotte title: The BAS²IC score: a useful tool to identify patients at high risk of early progression to severe COVID-19 date: 2020-09-01 words: 1628 flesch: 46 summary: Rapid identification of patients at a high risk of developing severe COVID-19 appeared to be crucial to help clinicians closely monitor such patients and for triage. On the contrary, those with score >14 were considered to have a high risk, requiring rapid implementation of appropriate measures, such as hospitalization and consideration of specific therapeutics (e.g. dexamethasone, remdesivir) keywords: covid-19; patients; risk; score cache: cord-032268-oj94e8wo.txt plain text: cord-032268-oj94e8wo.txt item: #6 of 40 id: cord-252305-rstxyofq author: Tyan, Kevin title: Considerations for the Selection and Use of Disinfectants Against SARS-CoV-2 in a Healthcare Setting date: 2020-08-31 words: 2063 flesch: 36 summary: However, limited guidance exists on effective surface disinfectants or best practices for their use against SARS-CoV-2. Limited guidance exists on effective surface disinfectants or best practices for disinfectant use against SARS-CoV-2. keywords: cov-2; disinfectants; sars cache: cord-252305-rstxyofq.txt plain text: cord-252305-rstxyofq.txt item: #7 of 40 id: cord-252751-prock3co author: Kalligeros, Markos title: Remdesivir Use Compared to Supportive Care in Hospitalized Patients with Severe COVID-19: A Single-Center Experience date: 2020-08-06 words: 3964 flesch: 46 summary: For the purposes of the present study we created a control group consisting of hospitalized patients with PCR confirmed COVID-19 who did not receive remdesivir. The US Food and Drug Administration issued an Emergency Use Authorization for remdesivir use in patients with severe COVID-19. keywords: covid-19; patients; remdesivir; study; time; trial; use cache: cord-252751-prock3co.txt plain text: cord-252751-prock3co.txt item: #8 of 40 id: cord-256130-zhlvvuj4 author: Nordén, Rickard title: Quantification of Torque Teno Virus and Epstein-Barr Virus Is of Limited Value for Predicting the Net State of Immunosuppression After Lung Transplantation date: 2018-03-06 words: 4856 flesch: 42 summary: When Tacrolimus was the main immunosuppressive treatment, TTV DNA levels were significantly elevated 6–24 months after transplantation as compared with Cyclosporine treatment. To compare results regarding TTV levels between different transplantation centers, it is vital to reliably quantify the concentrations of TTV-DNA in a standardized manner. keywords: dna; ebv; infection; levels; lung; months; patients; pcr; time; transplantation; ttv; virus cache: cord-256130-zhlvvuj4.txt plain text: cord-256130-zhlvvuj4.txt item: #9 of 40 id: cord-256195-1hmzgwrw author: Izzy, Saef title: Characteristics and outcomes of Latinx patients with COVID-19 in comparison to other ethnic and racial groups date: 2020-09-01 words: 4110 flesch: 37 summary: 15, 26 Our firsthand clinical experience with COVID-19 patients indicate that in addition to African American patients, a higher percentage of COVID-19 Latinx patients required hospitalization and critical care admission. 10, 11 Hypertension, heart disease, obesity, and diabetes are common comorbidities associated with hospitalization in COVID-19 patients. keywords: african; american; comorbidities; covid-19; disease; hospitalization; latinx; patients cache: cord-256195-1hmzgwrw.txt plain text: cord-256195-1hmzgwrw.txt item: #10 of 40 id: cord-258113-mnou31j3 author: Wang, Yaping title: Clinical Characteristics of Patients Infected With the Novel 2019 Coronavirus (SARS-Cov-2) in Guangzhou, China date: 2020-05-19 words: 3900 flesch: 52 summary: Imported group patients were those who had been to Wuhan within 14 days or who were residents of Wuhan before admission, and the local group included patients who had not left Guangdong during the past month. So it is important to evaluate ALB levels dynamically in these patients. RT-PCR analysis of respiratory or fecal samples, together with serological testing, can confirm the diagnosis of SARS-CoV infection in most SARS patients. keywords: coronavirus; cov-2; disease; group; patients; sars; study; wuhan cache: cord-258113-mnou31j3.txt plain text: cord-258113-mnou31j3.txt item: #11 of 40 id: cord-259969-q65k590s author: Kösters, Katrin title: Cutaneous Vasculitis in a Patient With COVID-19 date: 2020-10-05 words: 829 flesch: 40 summary: However, other groups have described skin manifestations in up to 20% of COVID patients [4, 5] . However, our case demonstrates a small/medium-sized vessel vasculitis with involvement of mucous membranes as the cause of skin manifestations in a patient with COVID-19 that appeared late in the disease. keywords: covid-19; patient; skin cache: cord-259969-q65k590s.txt plain text: cord-259969-q65k590s.txt item: #12 of 40 id: cord-260257-phmd0u6d author: Siegler, Aaron J title: Willingness to seek laboratory testing for SARS-CoV-2 with home, drive-through, and clinic-based specimen collection locations date: 2020-06-30 words: 3715 flesch: 44 summary: Differences in mean willingness scores across testing modalities were all significant (p<.001), with very small effect size for home saliva testing compared to home throat swab testing (d=0.12), medium effect size for home saliva testing compared to drive-through testing (d=0.55), and large effect size for home saliva testing compared to clinic-based testing (d=0.81). There was a hierarchy of willingness to test for SARS-CoV-2 that was decreased as the required degree of contact with healthcare systems increased: home testing was most preferred, followed by drive-through testing, and then by laboratory or clinicbased testing. keywords: collection; covid-19; drive; home; sars; specimen; testing; willingness cache: cord-260257-phmd0u6d.txt plain text: cord-260257-phmd0u6d.txt item: #13 of 40 id: cord-261619-31jk1vh6 author: Lindholm, David A title: Outcomes of Coronavirus Disease 2019 Drive-Through Screening at an Academic Military Medical Center date: 2020-07-17 words: 2181 flesch: 44 summary: Although our testing protocol focused on symptomatic patients, a universal-testing program in South Korea found that 2.6% of asymptomatic patients without a history of close contact tested positive [11] . Open Forum Infect Dis DOI: 10.1093/ofid/ofaa306 sha: doc_id: 261619 cord_uid: 31jk1vh6 Drive-through coronavirus disease 2019 screening can evaluate large numbers of patients while reducing healthcare exposures and personal protective equipment use. keywords: covid-19; drive; patients; sars; screening; testing cache: cord-261619-31jk1vh6.txt plain text: cord-261619-31jk1vh6.txt item: #14 of 40 id: cord-267023-w5ig7mrl author: Nori, Priya title: Developing Interactive Antimicrobial Stewardship and Infection Prevention Curricula for Diverse Learners: A Tailored Approach date: 2017-07-20 words: 4348 flesch: 31 summary: Commentary: IDSA guidelines for improving the teaching of preclinical medical microbiology and infectious diseases Faculty and resident physicians' attitudes, perceptions, and knowledge about antimicrobial use and resistance Medical students' perceptions and knowledge about antimicrobial stewardship: how are we educating our future prescribers? Implementing an Antibiotic Stewardship Program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America Hand-hygiene behaviour, attitudes and beliefs in first year clinical medical students Now please wash your hands': the handwashing behaviour of final MBBS candidates Usage of ultraviolet test method for monitoring the efficacy of surgical hand rub technique among medical students Critical gaps in knowledge of the epidemiology and pathophysiology of healthcare-associated infections Hand hygiene in medical students: performance, education and knowledge Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship New societal approaches to empowering antibiotic stewardship CMS Issues Proposed Rule that Prohibits Discrimination, Reduces Hospital-Acquired Conditions, and Promotes Antibiotic Stewardship in Hospitals Health care provider education as a tool to enhance antibiotic stewardship practices Is there an app for that? Likewise, studies in medical student education reveal (1) poor knowledge and practices of infection prevention and (2) gaps in understanding of healthcare-associated infections (HAIs) due to lack of emphasis and suboptimal practices among supervising physicians [5] [6] [7] [8] . keywords: antibiotics; app; infection; ipc; knowledge; prescribing; prevention; stewardship; students; use; year cache: cord-267023-w5ig7mrl.txt plain text: cord-267023-w5ig7mrl.txt item: #15 of 40 id: cord-268662-mw8ec7u2 author: Salton, Francesco title: Prolonged low-dose methylprednisolone in patients with severe COVID-19 pneumonia date: 2020-09-12 words: 4410 flesch: 40 summary: No tracheostomy was necessary in MP patients vs. 12 controls (OR 0.04, 95% CI 0.002 to 0.64, p-value <0.001). [1] COVID-19 patients with ARF necessitate weeks of mechanical ventilation (MV) and have an unacceptably high mortality rate. keywords: covid-19; days; fio; icu; pao; patients; pneumonia; study; treatment cache: cord-268662-mw8ec7u2.txt plain text: cord-268662-mw8ec7u2.txt item: #16 of 40 id: cord-268975-xzdh8yum author: Huang, Jing title: Public behavior change, perceptions, depression, and anxiety in relation to the COVID-19 outbreak date: 2020-07-03 words: 2600 flesch: 50 summary: The prevalence of public behaviors, perceptions, depression, and anxiety changed less than 1% or marginally 1% after weighting procedure, therefore the unweighted data were used for analysis in this study. Public protective behaviors and perception play crucial roles in controlling the spread of illness and psychological status. keywords: c r; outbreak; public cache: cord-268975-xzdh8yum.txt plain text: cord-268975-xzdh8yum.txt item: #17 of 40 id: cord-270703-c8mv2eve author: Christensen, Paul A title: Real-time Communication With Health Care Providers Through an Online Respiratory Pathogen Laboratory Report date: 2018-11-30 words: 1680 flesch: 43 summary: In addition, clinical laboratories should routinely monitor local influenza data to determine if epidemics are occurring, if continued testing is necessary, or if patients can be treated based on positive symptoms alone [2, 3] . Open Forum Infect Dis DOI: 10.1093/ofid/ofy322 sha: doc_id: 270703 cord_uid: c8mv2eve We implemented a real-time report to distribute respiratory pathogen data for our 8-hospital system to anyone with an Internet connection and a web browser. keywords: data; influenza; report; system; time cache: cord-270703-c8mv2eve.txt plain text: cord-270703-c8mv2eve.txt item: #18 of 40 id: cord-274943-fn3m14cn author: Philpott, Erin K title: Febrile Rhinovirus Illness During Pregnancy Is Associated With Low Birth Weight in Nepal date: 2017-04-06 words: 4858 flesch: 42 summary: Multivariate regression analysis evaluated the association between febrile HRV respiratory illness and adverse birth outcomes. The frequencies of each adverse outcome were compared between infants born to mothers with febrile HRV respiratory illness during pregnancy and those without febrile HRV respiratory illness during pregnancy. keywords: birth; febrile; hrv; illness; infants; lbw; pregnancy; rhinovirus; women cache: cord-274943-fn3m14cn.txt plain text: cord-274943-fn3m14cn.txt item: #19 of 40 id: cord-279334-j0i9ozsz author: McCreary, Erin K title: Coronavirus Disease 2019 Treatment: A Review of Early and Emerging Options date: 2020-03-23 words: 8289 flesch: 41 summary: The diagnosis and treatment guide of COVID-19 pneumonia caused by new coronavirus infection 7th Edition Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore Case of the index patient who caused tertiary transmission of COVID-19 infection in Korea: the application of lopinavir/ritonavir for the treatment of COVID-19 infected pneumonia monitored by quantitative RT-PCR The course of clinical diagnosis and treatment of a case infected with coronavirus disease 2019 Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 Pharmacokinetics of lopinavir/ritonavir crushed versus whole tablets in children Nitazoxanide, a new drug candidate for the treatment of Middle East respiratory syndrome coronavirus Effect of nitazoxanide in adults and adolescents with acute uncomplicated influenza: a double-blind, randomised, placebo-controlled, phase 2b/3 trial Efficacy and safety of nitazoxanide in addition to standard of care for the treatment of severe acute respiratory illness Tocilizumab for the treatment of chimeric antigen receptor T cell-induced cytokine release syndrome ASTCT consensus grading for cytokine release syndrome and neurologic toxicity associated with immune effector cells Cytokine release syndrome grade as a predictive marker for infections in patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with chimeric antigen receptor T cells FDA approval summary: tocilizumab for treatment of chimeric antigen receptor T cell-induced severe or life-threatening cytokine release syndrome Effective treatment of severe COVID-19 patients with tocilizumab SARS: systematic review of treatment effects Treatment of severe acute respiratory syndrome with glucosteroids: the Guangzhou experience Effects of early corticosteroid treatment on plasma SARS-associated coronavirus RNA concentrations in adult patients The use of corticosteroid as treatment in SARS was associated with adverse outcomes: a retrospective cohort study Corticosteroid therapy for critically ill patients with Middle East respiratory syndrome Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China On the use of corticosteroids for 2019-nCoV pneumonia Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area There are 4 clinical trials currently enrolling patients in the United States (Table 1) . keywords: activity; clinical; cov-2; covid-19; data; day; disease; hydroxychloroquine; lpv; patients; sars; therapy; treatment; use; vitro cache: cord-279334-j0i9ozsz.txt plain text: cord-279334-j0i9ozsz.txt item: #20 of 40 id: cord-282862-kve6fa49 author: Pastick, Katelyn A title: A Systematic Review of Treatment and Outcomes of Pregnant Women with COVID-19 – A Call for Clinical Trials date: 2020-08-13 words: 3317 flesch: 39 summary: We then evaluated the proportion of COVID-19 clinical trials (from Clinicaltrials.gov) excluding pregnant or breastfeeding persons (both through June 29(th), 2020). A second search was conducted to identify COVID-19 clinical trials as of June 29th, 2020 that reported pregnancy/breastfeeding as an exclusion criterion. keywords: breastfeeding; covid-19; outcomes; pregnancy; studies; trials; women cache: cord-282862-kve6fa49.txt plain text: cord-282862-kve6fa49.txt item: #21 of 40 id: cord-288044-ver1nrsz author: Sierra, Beatriz title: Association of early nasopharyngeal immune markers with COVID-19 clinical outcome: predictive value of CCL2/MCP-1 date: 2020-09-03 words: 1938 flesch: 40 summary: We hypothesized that the activity of this set of cytokines/chemokines could trigger/suppress the severe outcome of infection, resulting in confirmed COVID-19 patients with asymptomatic infections or different clinical evolutions. Dyspnea has been reported to be more frequent in COVID-19 severe cases, and indeed, in some studies, it was included as a marker of severe disease (15, 16) . keywords: evolution; patients cache: cord-288044-ver1nrsz.txt plain text: cord-288044-ver1nrsz.txt item: #22 of 40 id: cord-296890-08kqtw8s author: Toh, Teck-Hock title: High Prevalence of Viral Infections Among Hospitalized Pneumonia Patients in Equatorial Sarawak, Malaysia date: 2019-02-13 words: 4332 flesch: 46 summary: T One pediatric patient specimen destroyed, assay results out of n = 599. Surveillance for emerging respiratory viruses Global epidemiology of non-influenza RNA respiratory viruses: data gaps and a growing need for surveillance Addressing the public health burden of respiratory viruses: the Battle against Respiratory Viruses (BRaVe) initiative Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory tract infections in 195 countries: a systematic analysis for the Global Burden of Disease Study Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis Global burden of childhood pneumonia and diarrhoea Clinical and economic burden of community-acquired pneumonia amongst adults in the Asia-Pacific region The bacterial aetiology of adult community-acquired pneumonia in Asia: a systematic review Assessing the burden of pneumonia using administrative data from Malaysia, Indonesia, and the Philippines Epidemiology and seasonality of respiratory viral infections in hospitalized children in Kuala Lumpur, Malaysia: a retrospective study of 27 years Surveillance for respiratory syncytial virus and parainfluenza virus among patients hospitalized with pneumonia in Sarawak Community-acquired pneumonia requiring hospitalization among U.S. children Community-acquired pneumonia requiring hospitalization among U.S. adults Humidity as a non-pharmaceutical intervention for influenza A Absolute humidity modulates influenza survival, transmission, and seasonality Respiratory syncytial virus-a comprehensive review Pneumonia: a global cause without champions Respiratory syncytial virus subtype A was detected in the third patient's NP swab. keywords: age; hospital; patients; pneumonia; prevalence; rsv; sibu; specimens; study; years cache: cord-296890-08kqtw8s.txt plain text: cord-296890-08kqtw8s.txt item: #23 of 40 id: cord-303091-jky6jlrl author: Cellai, Michele title: Characterization of prolonged COVID-19 symptoms in an outpatient telemedicine clinic date: 2020-09-12 words: 1951 flesch: 51 summary: Due to the presence of persistent symptoms, 16 (61.5%) of patients delayed return to work at least five weeks from symptom onset, 17 (65.3%) delayed return to activity. jky6jlrl We identified patients with coronavirus disease 2019 (COVID-19) in a telemedicine clinic who requested ongoing follow-up calls 6 weeks after symptom onset. keywords: patients; symptoms cache: cord-303091-jky6jlrl.txt plain text: cord-303091-jky6jlrl.txt item: #24 of 40 id: cord-303935-qdehf6rb author: Yun, Heather C. title: Changes in Clinical Presentation and Epidemiology of Respiratory Pathogens Associated With Acute Respiratory Illness in Military Trainees After Reintroduction of Adenovirus Vaccine date: 2015-09-01 words: 4254 flesch: 39 summary: Because respiratory illness remains a leading cause of presentation for care among military trainees, understanding of trends in clinical presentation and emerging, non-Ad respiratory pathogens in the post-VI era requires evaluation. Ill or injured trainees present for care at an outpatient medical clinic; those with respiratory illness and fever are then cohorted until well enough to return to training. keywords: illness; military; post; rhinovirus; study; trainees; vaccine cache: cord-303935-qdehf6rb.txt plain text: cord-303935-qdehf6rb.txt item: #25 of 40 id: cord-305512-p5qchjva author: Alghamdi, Abdulaziz title: Molecular Evidence of Influenza A Virus Circulation in African Dromedary Camels Imported to Saudi Arabia, 2017–2018 date: 2019-09-30 words: 2605 flesch: 39 summary: Several outbreaks of severe respiratory diseases in bactrian camels have occurred between 1978 and 1988 in Mongolia and were suspected to be due to influenza viruses [7] . Although the existence of influenza viruses in dromedary camels has not been investigated properly, previous studies provided limited serological evidence of circulation of all influenza types (A, B, C, and D) among dromedaries in several African countries [9] [10] [11] . keywords: animals; camels; h1n1; influenza; samples; table; viruses cache: cord-305512-p5qchjva.txt plain text: cord-305512-p5qchjva.txt item: #26 of 40 id: cord-310807-p5cb6idp author: Kanwar, Anubhav title: Human Coronavirus-HKU1 Infection Among Adults in Cleveland, Ohio date: 2017-03-25 words: 2957 flesch: 44 summary: A systematic review and meta-analysis of randomized controlled trials Etiology and clinical characterization of respiratory virus infections in adult patients attending an emergency department in Beijing Detection of the new human coronavirus HKU1: a report of 6 cases Human coronaviruses are uncommon in patients with gastrointestinal illness Prevalence of gastrointestinal symptoms in patients with influenza, clinical significance, and pathophysiology of human influenza viruses in faecal samples: what do we know Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection Viral shedding and antibody response in 37 patients with middle east respiratory syndrome coronavirus infection Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method Use of a novel virus detection assay to identify coronavirus HKU1 in the lungs of a hematopoietic stem cell transplant recipient with fatal pneumonia A prospective hospital-based study of the clinical impact of non-severe acute respiratory syndrome (Non-SARS)-related human coronavirus infection Antibiotic discontinuation rates associated with positive respiratory viral panel and low procalcitonin results in proven or suspected respiratory infections Impact of antibacterials on subsequent resistance and clinical outcomes in adult patients with viral pneumonia: an opportunity for stewardship Access to a polymerase chain reaction assay method targeting 13 respiratory viruses can reduce antibiotics: a randomised, controlled trial The role of infections and coinfections with newly identified and emerging respiratory viruses in children Rate and influence of respiratory virus co-infection on pandemic (H1N1) influenza disease Detection of four human coronaviruses in respiratory infections in children: a one-year study in Colorado Coronavirus-HKU1 accounted for 1.6% of adult respiratory infections and should be considered in differential diagnosis of severe respiratory illnesses among adults. keywords: adults; coronavirus; cov; disease; hku1; patients; respiratory; study cache: cord-310807-p5cb6idp.txt plain text: cord-310807-p5cb6idp.txt item: #27 of 40 id: cord-310872-2z1wnj63 author: Spellberg, Brad title: Alignment With Market Forces: The “Re-Whithering” of Infectious Diseases date: 2020-06-20 words: 2903 flesch: 49 summary: Indeed, ID practitioners are 1 of only 2 subspecialties remunerated below general internists in the United States [8] , raising the obvious questionwhy should top talent choose to spend 2 or more additional years in training to end up making less money? First, ID practitioners have unique expertise in the diagnosis and treatment of infections, which can lead to less antimicrobial resistance and superinfections, better outcomes, and lower cost for patients and health systems. keywords: forces; health; healthcare; market; system; years cache: cord-310872-2z1wnj63.txt plain text: cord-310872-2z1wnj63.txt item: #28 of 40 id: cord-311082-sspcz9t6 author: Chen, Shi title: Four Challenges Associated With Current Mathematical Modeling Paradigm of Infectious Diseases and Call for a Shift date: 2020-08-07 words: 1528 flesch: 31 summary: SEIR models are mechanistic models developed almost a century ago [3] . Second, SEIR models are formulated at the population level. keywords: covid-19; modeling; models; seir cache: cord-311082-sspcz9t6.txt plain text: cord-311082-sspcz9t6.txt item: #29 of 40 id: cord-314517-n1yj2zdy author: Huang, Dayong title: Social media survey and web posting assessment of the COVID-19 response in China: Health worker attitudes towards preparedness and personal protective equipment shortages date: 2020-08-31 words: 2947 flesch: 47 summary: While we did not indicated exclusion criteria in the recruitment poster (supplemental Fig 1) , we specified our research aims regarding self-perception of health worker preparedness. We conducted a cross-sectional survey from February 24-28, 2020 to assess COVID-19 preparedness among health workers. keywords: confidence; covid-19; health; ppe; preparedness; workers cache: cord-314517-n1yj2zdy.txt plain text: cord-314517-n1yj2zdy.txt item: #30 of 40 id: cord-320511-qnxj7d9l author: Hueston, Linda title: The antibody response to SARS-CoV-2 infection date: 2020-08-27 words: 3122 flesch: 37 summary: False Positive Results with BD SARS-CoV-2 Reagents for the BD Max System -Letter to Clinical Laboratory Staff and Health Care Providers Public Health Laboratory Network Statement on Nucleic Acid Test False Positive Results for SARS-CoV-2 Interpret with caution: An evaluation of the commercial AusDiagnostics versus in-house developed assays for the detection of SARS-CoV-2 virus False-positive reverse transcriptase polymerase chain reaction screening for SARS-CoV-2 in the setting of urgent head and neck surgery and otolaryngologic emergencies during the pandemic: Clinical implications Real-time RT-PCR in COVID-19 detection: issues affecting the results IgA-Ab response to spike glycoprotein of SARS-CoV-2 in patients with COVID-19: A longitudinal study Persistence of Antibodies against Middle East Respiratory Syndrome Coronavirus Duration of antibody responses after severe acute respiratory syndrome Longitudinal profile of antibodies against SARS-coronavirus in SARS patients and their clinical significance Viral Shedding and Antibody Response in 37 Patients With Middle East Respiratory Syndrome Coronavirus Infection Kinetics of Serologic Responses to MERS Coronavirus Infection in Humans MERS-CoV Antibody Responses 1 Year after Symptom Onset, South Korea A comparison study of SARS-CoV-2 IgG antibody between male and female COVID-19 patients: a possible reason underlying different outcome between sex Profile of specific antibodies to SARS-CoV-2: The first report Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients Virological assessment of hospitalized patients with COVID-2019 Long-term coexistence of SARS-CoV-2 with antibody response in COVID-19 patients Rapid point-of-care testing for SARS-CoV-2 in a community screening setting shows low sensitivity The magnitude and persistence of antibody responses are critical for assessing the duration of immunity. keywords: antibody; cov-2; covid-19; ifa; nat; positive; sars cache: cord-320511-qnxj7d9l.txt plain text: cord-320511-qnxj7d9l.txt item: #31 of 40 id: cord-321000-3jd2gn73 author: Karra, Nour title: A Case of Hemophagocytic Lymphohistiocytosis Associated With Mediterranean Spotted Fever in a Healthy 29-Year-Old Female date: 2020-08-13 words: 3082 flesch: 34 summary: Second, many diagnostic criteria are nonspecific (fever, cytopenias, hypofibrinogenemia) and may be encountered Contrarily, HLH patients frequently exhibit findings other than those included in the diagnostic criteria (hypoalbuminemia, elevated liver enzymes, coagulopathy). An increasing number of acquired HLH cases have been reported in recent years [3] . keywords: cases; diagnosis; fever; hlh; lymphohistiocytosis; rickettsia; syndrome; treatment cache: cord-321000-3jd2gn73.txt plain text: cord-321000-3jd2gn73.txt item: #32 of 40 id: cord-322524-bq9ok8h1 author: Belongia, Edward A title: Clinical Features, Severity, and Incidence of RSV Illness During 12 Consecutive Seasons in a Community Cohort of Adults ≥60 Years Old date: 2018-11-27 words: 5191 flesch: 39 summary: Additional studies are needed in diverse populations to estimate the burden of adult RSV illness and the potential impact of future licensed vaccines. Samples collected from the 2004-2005 through 2009-2010 seasons were previously tested using the GenMark multiplex assay in a separate study of RSV illness in adults ≥50 years of age [19] . keywords: adults; enrollment; illness; influenza; patients; rsv; study; syncytial; virus; years cache: cord-322524-bq9ok8h1.txt plain text: cord-322524-bq9ok8h1.txt item: #33 of 40 id: cord-326642-kc85pev4 author: Cohen, Adam L. title: Parainfluenza Virus Infection Among Human Immunodeficiency Virus (HIV)-Infected and HIV-Uninfected Children and Adults Hospitalized for Severe Acute Respiratory Illness in South Africa, 2009–2014 date: 2015-09-19 words: 4063 flesch: 45 summary: A preliminary study of pneumonia etiology among hospitalized children in Kenya Severe influenza-associated lower respiratory tract infection in a high HIV-prevalence setting-South Africa Severe lower respiratory tract infections associated with human parainfluenza viruses 1-3 in children infected and non-infected with HIV type 1 An investigation into the prevalence and outcome of patients admitted to a pediatric intensive care unit with viral respiratory tract infections in Cape Town, South Africa Respiratory viral coinfections identified by a 10-plex real-time reverse-transcription polymerase chain reaction assay in patients hospitalized with severe acute respiratory illness-South Africa Epidemiology of severe acute respiratory illness among adults and children aged ≥5 years in a high HIV-prevalence setting Epidemiology of viral-associated acute lower respiratory tract infection among children <5 years of age in a high HIV prevalence setting Evaluation and improvement of real-time PCR assays targeting lytA, ply, and psaA genes for detection of pneumococcal DNA Population-based incidence of severe acute respiratory virus infections among children aged <5 years in rural Bangladesh Viral etiologies of hospitalized acute lower respiratory infection patients in China Hospitalization due to human parainfluenza virus-associated lower respiratory tract illness in rural Thailand Etiology and epidemiology of viral pneumonia among hospitalized children in rural Mozambique: a malaria endemic area with high prevalence of human immunodeficiency virus Incidence and etiology of acute lower respiratory tract infections in hospitalized children younger than 5 years in rural Thailand Interaction between influenza virus and Streptococcus pneumoniae in severe pneumonia Association between respiratory syncytial virus activity and pneumococcal disease in infants: a time series analysis of US hospitalization data Seasonal trends of human parainfluenza viral infections: United States Viral etiology of influenza-like illnesses in Cameroon Progress in the development of human parainfluenza virus vaccines In our second analysis, univariate and multivariable logistic regression was used to determine factors associated with HIV infection among patients with PIV-associated SARI from January 2009 to December 2014 at all SARI sites. keywords: age; children; hiv; piv; sari; type; years cache: cord-326642-kc85pev4.txt plain text: cord-326642-kc85pev4.txt item: #34 of 40 id: cord-327609-no58ucyq author: Murkey, Jamie A. title: Hepatitis E Virus–Associated Meningoencephalitis in a Lung Transplant Recipient Diagnosed by Clinical Metagenomic Sequencing date: 2017-06-13 words: 1954 flesch: 30 summary: Validation of metagenomic next-generation sequencing tests for universal pathogen detection Neurobrucellosis: unexpected answer from metagenomic next-generation sequencing Hepatitis E virus reinfections in solid-organ-transplant recipients can evolve into chronic infections Hepatitis E virus infection among solid organ transplant recipients, the Netherlands Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants Hepatitis E virus and neurologic disorders Evidence of hepatitis E virus breaking through the blood-brain barrier and replicating in the central nervous system A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples Treatment of HEV infection in patients with a solid-organ transplant and chronic hepatitis Liver transplant from a donor with occult HEV infection induced chronic hepatitis and cirrhosis in the recipient Evidence of hepatitis E virus transmission by renal graft We would like to thank the patient for participating in the PDAID research study. We demonstrate the power of clinical mNGS in elucidating the cause of uncommon and unexpected infections and identify a case of chronic HEV infection most likely transmitted through the transplanted lungs the patient had received 6 years prior. keywords: chronic; hepatitis; hev; infection; patient; transplant; virus cache: cord-327609-no58ucyq.txt plain text: cord-327609-no58ucyq.txt item: #35 of 40 id: cord-333459-asem8xjz author: Mallipattu, S K title: Geospatial Distribution and Predictors of Mortality in Hospitalized Patients with COVID-19: A Cohort Study date: 2020-09-14 words: 3206 flesch: 41 summary: Study patients were predominantly hypertensive (MAP>90mmHg (670, 51%)) The global Coronavirus Disease 2019 (COVID-19) pandemic offers the opportunity to assess how hospitals managed the care of hospitalized patients with varying demographics and clinical presentation. keywords: covid-19; kidney; mortality; patients cache: cord-333459-asem8xjz.txt plain text: cord-333459-asem8xjz.txt item: #36 of 40 id: cord-334210-lhadzo7o author: Lepak, Alexander J title: Utility of Repeat Nasopharyngeal SARS-CoV-2 RT-PCR Testing and Refinement of Diagnostic Stewardship Strategies at a Tertiary Care Academic Center in a low Prevalence Area of the United States date: 2020-08-27 words: 3674 flesch: 46 summary: Advice on which procedures met criteria was circulated to all providers, but, as with repeat PUI testing, proper test utilization was not actively enforced. The remainder of inpatients tested negative on repeat PUI testing. keywords: negative; pui; repeat; sars; testing cache: cord-334210-lhadzo7o.txt plain text: cord-334210-lhadzo7o.txt item: #37 of 40 id: cord-347255-fl9lur4h author: May, Larissa title: Rapid Multiplex Testing for Upper Respiratory Pathogens in the Emergency Department: A Randomized Controlled Trial date: 2019-11-05 words: 4067 flesch: 34 summary: Thus, we conducted a randomized clinical trial of the FilmArray RP vs usual care in ED patients with signs or symptoms of upper respiratory infection or influenza-like illness. We conducted a prospective, patient-oriented, pilot randomized clinical trial of rapid multiplex respiratory pathogen testing (RP test group) vs usual care (usual care or control group) in a level 1 emergency department with limited use of single-organism rapid point-of-care tests at a quaternary referral medical center. keywords: antibiotic; care; influenza; patients; results; study; testing cache: cord-347255-fl9lur4h.txt plain text: cord-347255-fl9lur4h.txt item: #38 of 40 id: cord-350557-7i7122zi author: Rawlings, Stephen A title: No Evidence of SARS-CoV-2 Seminal Shedding Despite SARS-CoV-2 Persistence in the Upper Respiratory Tract date: 2020-08-07 words: 1756 flesch: 49 summary: All 6 semen samples were negative for SARS CoV-2 (≤0.03 copies/µL), while SARS-CoV-2 was still detected in all saliva samples (6 participants) and all research nasal swabs (3 participants). Paired saliva and semen samples were collected a mean of 12 days (6-17 days) after the onset of symptoms, and ddPCR was performed to quantify the SARS-CoV-2 level in all samples. keywords: rna; samples; sars; semen; symptoms cache: cord-350557-7i7122zi.txt plain text: cord-350557-7i7122zi.txt item: #39 of 40 id: cord-350767-6kc4hyzo author: Beh, Darius L L title: The Pandemic Academy: Reflections of Infectious Diseases Fellows During COVID-19 date: 2020-06-25 words: 2467 flesch: 49 summary: As we mark 3 months of our fellowship in the COVID-19 era, we reflect on our experiences and the unique impact of this pandemic on ID fellows. Strange as it may be for ID fellows, our specific role during a pandemic of this scale is not well-defined. keywords: covid-19; fellows; pandemic cache: cord-350767-6kc4hyzo.txt plain text: cord-350767-6kc4hyzo.txt item: #40 of 40 id: cord-351022-8y43jhmu author: Schwartz, Carmela title: A dynamic response to exposures of healthcare workers to newly diagnosed COVID-19 patients or hospital personnel, in order to minimize cross transmission and need for suspension from work during the outbreak date: 2020-09-01 words: 2902 flesch: 50 summary: Furthermore, immediate epidemiological investigation and, if needed, early suspension from work of exposed HCWs is needed in order to limit the spread of infection to and between HCWs and patients (7) (8) . Immediate epidemiological investigations of exposed HCWs were initiated, in order to break the chain of cross-transmission between HCWs as well as avoiding transmission from HCWs to patients, thus keeping maximal work force available. keywords: covid-19; hcws; isolation; work cache: cord-351022-8y43jhmu.txt plain text: cord-351022-8y43jhmu.txt