Microsoft Word - 16SirbuMinimallyInvasive Romanian Neurosurgery (2011) XVIII 1: 101 – 102 101 Minimally invasive plate osteosynthesis using systems with angular stability in complex fractures of the distal femur. Fashion or real advantages? Regenerative medicine as an option for bone regeneration P.D. Sîrbu1, T. Petreuș1, R. Asaftei1, C.E. Cotrutz1, E. Carata2, P. Botez1, S. Stratulat1 1“Gr.T. Popa” University of Medicine and Pharmacy, Iasi, Romania 2“Gh. Asachi” Technical University, Iasi, Romania Keywords: LISS, LCP, combi-holes, polyaxial stability, internal fixators Introduction Complex distal femoral fractures represent a challenge for orthopaedic surgeons. The disadvantages of classic surgery led to the development of new surgical techniques (minimally invasive plate osteosynthesis - MIPO and transarticular approach and retrograde plate osteosynthesis - TARPO) and new implants with angular stability (internal fixators). Aims The purpose of this study is to present the preliminary results in treating the distal femoral fractures with plates with angular stability and to exhibit the advantages and differences between these efficient systems. Material and methods The study included 22 fractures (4 type A2, 7 type A3, 6 type C2, and 5 type C3 AO). There were 2 periprosthetic knee fractures. The study included 4 open fractures: 2 - grade I, 1 grade II, and 1 grade IIIA (Gustilo). The authors used a Less Invasive Stabilization System (LISS) in 10 cases, Locked Compression Plate (LCP) with combi-holes in 6 cases, and plates with polyaxial stability in 6 cases. For extraarticular fractures, the plates were inserted through a minimally antero-lateral incision beneath the vastus lateralis (by means of an aiming device), after indirect, closed fracture reduction of the metaphysis and shaft area (MIPO technique). For articular fractures we have first performed a lateral parapatellar arthrotomy and reconstruction of the articular block (TARPO technique). Newer polyaxial locked plates were used in difficult type C3 distal femoral fractures due to some freedom in angulation of screws, prior to final screw plate sitting. Results and discussions All fractures less one (with bone loss which required bone grafting after three months) healed within a mean time of 13 weeks (with no infections, implant breakage or secondary displacement), These plates with angular stability represent the ideal treatment in difficult fractures with short distal fragment, osteoporotic fractures, fractures above knee 102 P.D. Sîrbu et al Minimally invasive plate osteosynthesis arthroplasties and some open fractures. The key to success for internal fixators are: correct/incorrect indications, the usage of the appropriate plates, proper fracture reduction before plate insertion and screw drilling, avoidance of the eccentric plates placement, full-weight bearing allowed when callus is seen in serial postoperative radiographs. The authors prefer the LCP system and a newer polyaxial locked plate due to their advantages of screw pathway adjustment. Conclusions Close cooperation between orthopaedic surgeon, biomechanics specialist and the departments of cell biology and pathology, will contribute to the development of the ideal internal fixator and will sustain the future experimental investigations in order to elucidate the dynamic and coherent process of callus formation with these biological plates and techniques. References 1. Frigg R., Appenzeller A, Christensen R., Frenk A, Gilbert S., Schavan R. “The development of the distal femur. Less Invasive Stabilization System (LISS)”, Injury, Int. J. Care Injured, 2001, 32, pp. 24-31. 2. Wagner M, Frigg R (eds) AO Manual of fracture management – Internal Fixators. Thieme Stuttgart (2006) 3. Richter M, Droste P, Goesling T, Zech S, Krettek C. - Polyaxially-locked plate screws increase stability of fracture fixation in an experimental model of calcaneal fracture. J Bone Joint Surg Br. 2006 Sep;88(9):1257-63. 4. Sirbu P.D., Schwarz N., Belangero V.D., Livani B., List M., Botez P., Mihaila R.I. Minimally invasive plate ostheosynthesis in long bone fractures, Casa de Editura Venus, Iasi, Romania 2008. 5. Sirbu P.D., Friedl W., Botez P., Stratan L., Hopulele S., Asaftei R. Osteosinteza minim invaziva cu placi - Fixatoare interne, Casa de Editura Venus, Iasi, Romania 2008 6. Ip David, Orthopedic Traumatology – A Resident’s Guide; Springer Berlin-Heidelberg 2006