Figure 2. OBS Clinical Grading Improvements in Ashen Appearance 
and Dry Skin Parameters

Figure 3. OBS Improved Ashen Appearance, Dryness, Flaking, 
Tactile Roughness and Radiance After 2 Weeks of Daily Use

Figure 4. OBS and AHO Significantly Improved Dryness, Scaling, 
Cracking, and Roughness

Figure 5. Comparison of Daily OBS and AHO for Treatment of Dry 
Heel Skin Demonstrated Comparable Efficacy

INTRODUCTION RESULTS

RESULTS

CONCLUSIONS

CONCLUSIONS

METHODS

METHODS

OBJECTIVE

OBJECTIVE

(OBS) on large areas of dry, ashen skin of women with darker skin 
complexions

skin on heels compared to Aquaphor Healing Ointment (AHO)

at Week 1 (p<0.05) and Week 2 (p<0.001) compared with baseline 
and compared with untreated legs (p<0.05) (Figure 1)

parameters for both OBS and AHO at Days 5, 10, and 15 compared to 
baseline (p<0.001) (Figure 4)

(Figure 5)

such as the lower legs

skin on the heels, and were not statistically different

Subjects

Study design

assignment) for 2 weeks

Assessments

Subjects

Study design

the other once daily for 15 days

Assessments

TM Weber,1 CE Arrowitz,1 LI Jiang,2 K Qian,2 A Filbry3
1Beiersdorf Inc., Wilton, CT, USA; 2Thomas J. Stephens & Associates, Richardson, TX, USA; 3Beiersdorf AG, Hamburg, Germany

Efficacy of an Ointment Body Spray to Improve the Appearance of Dry, 
Ashy Skin and Alleviate Moderate to Severe Dryness on the Heel

Figure 1. OBS Significantly Improved Skin Hydration of Dry Skin 
Compared with Baseline and Untreated Skin

19.6 

23.5 24.9 

20.4 

20.1 

21.1 

10
12
14
16
18
20
22
24
26
28
30

Baseline Wk 1 Wk 2 

Treated 
Untreated 

N=31 

C
o

rn
eo

m
et

er
 U

n
it

s

Skin Hydration 

a,c b,c 

OBS=Ointment Body Spray 

ap<0.05 vs Baseline 
bp<0.001 vs Baseline 
cp<0.05 vs Control 

5.7 

4.3 

3.4 

5.8 5.8 5.8

0.0

1.0

2.0

3.0

4.0

5.0

6.0

7.0

Baseline Week 1 Week 2 
0.0

1.0

2.0

3.0

4.0

5.0

6.0

7.0

Baseline Week 1 Week 2 
0.0

1.0

2.0

3.0

4.0

5.0

6.0

7.0

Baseline Week 1 Week 2 

 Ashen Appearance 

M
ea

n
 C

lin
ic

al
 G

ra
d

in
g

 S
co

re
s 

a,b
a,b

a,b

a,b

5.7 
4.8 

4.1 

5.7 
5.9 5.9 

a,b

a,b

Dryness 

5.5 

4.1 

3.1 

5.5 
5.6 5.6 

Flaking 

N=31 ap<0.001 vs Baseline
bp<0.001 vs Control

Treated 
Untreated 

0

1

2

3

4

5

6

7

Baseline Day 5 Day 10 Day 15 Baseline Day 5 Day 10 Day 15 Baseline Day 5 Day 10 Day 15 Baseline Day 5 Day 10 Day 15 

M
ea

n
 C

lin
ic

al
 G

ra
d

in
g

 S
co

re
 

0

1

2

3

4

5

6

7
Scaling Dryness Cracking 

0

1

2

3

4

5

6

7

0

1

2

3

4

5

6

7

OBS 
AHO 

a a

a a

a a

a a

a
a

a a

a a

a
a

a a

a 
a 

a a 

a a 

Roughness 

N=18ap=0.001 vs Baseline 

Aquaphor Healing Ointment’s (AHO) efficacy in reducing moderately 
to severely dry skin is well established. However, application of 
ointments on large areas can be messy and challenging. 

Ointment Body Spray (OBS) was developed to enable the delivery 

Two clinical studies were conducted to evaluate the efficacy of OBS.

STUDY A

STUDY B

Untreated: Baseline

Untreated: Baseline

Treated: Baseline

Treated: Baseline

Untreated: Week 2 –  
No Change

Untreated: Week 2 –  
No Change

Treated: Week 2 –  
Clinical Improvement

Treated: Week 2 –  
Clinical Improvement

Baseline Day 15

OBS OBSAHO AHO

all parameters compared with baseline and untreated legs at Week 1 
and Week 2 (p<0.001) (Figure 2, tactile roughness and radiance data 
not shown)


	FC17PosterBeiersdorfWeberEfficacyOintmentHeel.pdf