D. MOYAL, S. SEITE
La Roche-Posay Dermatological Laboratories, Asnières, France

INTRODUCTION

RESULTS

HOW TO TREAT DRYNESS, HYPERKERATOSIS AND CRACKS OF DIABETIC PATIENTS FEET

Patients with diabetes frequently present skin changes on foot. The skin of the feet may 
become very dry with hyperkeratosis and cracks. We evaluated the use of a podologic 
dedicated emollient cream in the treatment of xerosis in diabetic foot.

3

2

1

0
D0 D14 D28

2,6

1,1

0,4

*

*

M
ea

n
 S

co
re

Evolution of Dryness Scoring

*p≤0.0001 compared to D0

% of subjects with change of dryness score

6%

94%

2%

98%

Improved Unchanged Worsened

D14 vs D0 D28 vs D0

3

2

1

0
D0 D14 D28

2,5

0,9
*

*
0,4

M
ea

n
 S

co
re

Evolution of Desquamation Scoring

*p≤0.0001 compared to D0

% of subjects with change 
of desquamation score

2%

98%
100%

D14 vs D0 D28 vs D0

Evolution of Roughness Scoring

Improved Unchanged Worsened

3

2

1

0
D0 D14 D28

M
ea

n
 S

co
re

2,4

0,9

0,2

*

*

*p≤0.0001 compared to D0

% of subjects with change 
of roughness score

2%

98%
100%

Improved Unchanged Worsened

D14 vs D0 D28 vs D0

Evolution of Hyperkeratosis Scoring

3

2

1

0
D0 D14 D28

2,7

1,9

1,2

*

*

M
ea

n
 S

co
re

*p≤0.0001 compared to D0

% of subjects with change 
of hyperkeratosis score

16%

84%

100%

Improved Unchanged Worsened

D14 vs D0 D28 vs D0

This study showed a very good tolerance of a specific podologic 
dermocosmetic on feet of diabetic patients including effectiveness in 
reducing the skin dryness, hyperkeratosis and cracks.

CONCLUSION

Tolerance : the product was well tolerated by all subjects after 28 days of application.

Subject 22 Left Foot Subject 51 Left Foot

D0 D28 D0 D28

METHODS
51 subjects (72.5% female, 27.5% male, 56 years old in average) suffering from type I 
(2%) or II (98%) diabetes participated in the study. All subjects had dryness and 
callosity on the feet with a minimum score of 2 out of 4 for dryness, hyperkeratosis, 
roughness and desquamation. Clinical signs were scored at T0 and after 4 weeks of 
application (twice a day) together with evaluation of skin tolerance and opinions of patients.


	FC17PosterLaRocheMoyalDiabeticFeet.pdf