PowerPoint Presentation PRESENTED AT THE FALL CLINICAL DERMATOLOGY CONFERENCE 2022 MEETING, OCTOBER 20–23, 2022, LAS VEGAS, NV, USA Figure 8. Reasons Patient Stopped Seeing HCP HCP: healthcare provider; SD: seborrheic dermatitis. n=43. Small sample size, results are qualitive in nature. Reason patient stopped seeing HCP Figure 7. HCP-Reported Path to SD Diagnosis HCP: healthcare provider; SD: seborrheic dermatitis. 77% 23% Directly to Dermatology HCP Referral from another HCP 50% with SD as primary complaint 27% with a different/ non-SD primary complaint 6% with SD diagnosis already 17% with a different/ non-SD diagnosis Figure 3. HCP- and Patient-Reported Time From Symptom Onset to Seeking Care HCP: healthcare provider. Figure 1. Patient Demographics and Disease Severity Patients: N=300; HCPs: N=601. HCP: healthcare provider. Figure 6. Non-HCPs Who Helped Patients Identify SD Symptoms HCP: healthcare provider; SD: seborrheic dermatitis. Figure 2. HCP Demographics HCPs (N=601) included dermatologists and NPs and PAs specializing in dermatology. HCP: healthcare provider; NP/PA: nurse practitioner/physician assistant; SD: seborrheic dermatitis. Figure 4. Patient-Reported Initial Perceptions of SD Prior to Diagnosis SD: seborrheic dermatitis. DISCLOSURES RC, LA, CH, MA, and MZ are investigators and/or consultants for Arcutis Biotherapeutics, Inc. and received grants/research funding and/or honoraria; DC, DH, and MS are employees of Arcutis Biotherapeutics, Inc. Additional disclosures provided on request. INTRODUCTION • Seborrheic dermatitis (SD) is a common chronic inflammatory skin disease with a worldwide prevalence of up to 5%1; however, little is known about patient and provider views, preferences, impressions, and path to diagnosis of SD • The authors developed an online survey, conducted by the Harris Poll, on burden, experiences, and preferences of patients with SD and healthcare providers (HCPs) • This poster presents the results related to the path to diagnosis of SD METHODS • The patient survey was conducted online from December 2021 through January 2022 among US adults diagnosed with SD by an HCP (Figure 1) – Figures for age, sex, education, race/ethnicity, region, income, household size, and marital status were weighted where necessary to bring the data into line with actual proportions in the population – Self-identified Black/African American patients were adjusted to natural fall out among the qualified patients – A propensity score variable was also included to adjust for respondents’ propensity to be online • The HCP survey was conducted online from December 2021 through January 2022 by HCPs specializing in dermatology (including dermatologists, nurse practitioners [NPs], and physician assistants [PAs]) who see ≥1 patient per week and ≥1 patient with SD per year (Figure 2) – For dermatologists, figures for years in practice, gender, and region were weighted where necessary to bring the data into line with actual proportions in the population – For NP/PAs, raw data were not weighted and are therefore only representative of the individuals who completed the survey RESULTS • HCPs underestimated the time it takes for patients experiencing SD symptoms to seek care, with HCPs reporting an average of 1.6 years from symptom onset to diagnosis while patients reported an average of 3.6 years (Figure 3) • A higher percentage of patients with severe disease reported visiting an HCP for their symptoms within 1 year (Figure 3) • Before diagnosis, 56% of patients said it was hard to find information online about SD and 71% said they had not heard of SD prior to diagnosis(Figure 4) – 86% of HCPs said that most patients had not heard of SD prior to their diagnosis • Most (83%) patients did not realize all their symptoms were due to SD and 76% mistook their symptoms for another skin condition (Figure 4) – Most HCPs agreed that patients did not realize all their symptoms were due to SD (96%) and thought they mistook their symptoms for another skin condition (91%) • Almost all (90%) patients wished they had known that there were specific symptoms to identify SD (Figure 4), with 85% of HCPs agreeing that their patients feel similarly • 63% of patients thought their symptoms were not severe enough to warrant medical attention, and the majority were embarrassed to talk to family or friends (59%) and HCPs (58%) about symptoms (Figure 5) • 77% of HCPs reported that patients come to them directly about SD, with 50% having SD as their primary complaint and 6% already having an SD diagnosis (Figure 7) • Most (79%) patients said they prefer a dermatology HCP for SD management CONCLUSIONS • Prior to diagnosis, most patients said they had not heard of SD and found it difficult to find information online • HCPs underestimated the time it takes for patients experiencing SD symptoms to reach out, with a 2-year difference between what HCPs thought and patients reported • These findings reveal major needs in optimization of diagnosis, management, and education for SD • Future studies are needed to better characterize and address these burdens Raj Chovatiya,1 Lakshi Aldredge,2 Candrice Heath,3 Moises Acevedo,4 David Chu,5 Diane Hanna,5 Melissa Seal,5 Matthew Zirwas6 1Northwestern University, Chicago, IL, USA; 2Veterans Administration Portland Health Care System, Portland, OR, USA; 3Temple University, Philadelphia, PA, USA; 4 Park Plaza Dermatology, New York, NY, USA; 5Arcutis Biotherapeutics, Westlake Village, CA, USA; 6Dermatologists of the Central States, Probity Medical Research, and Ohio University, Bexley, OH, USA Patient and Healthcare Provider Perspectives on the Path to Diagnosis of Seborrheic Dermatitis: Results From a National Survey of Adults With Seborrheic Dermatitis in the United States • Patients reported visiting an average of 2.3 HCPs for SD treatment and 75% have seen more than one HCP • Patients said they visit their primary HCP for SD management an average of 4.6 times per year, and 85% said they still actively work with their HCP for SD treatment – Of the 15% of patients who have stopped visiting their HCP, the reasons were improvement in symptoms (50%), ability to manage SD without prescription treatments (24%), and difficulty navigating insurance coverage for treatments (20%) (Figure 8) 90% of patients wish they had known that there are specific symptoms that can help identify SD 83% “I didn’t realize all of my symptoms (e.g., on face, body, scalp, etc.) were due to SD” agree 76% “I mistook my symptoms for a different type of skin condition” agree71% “I had not heard of SD prior to my diagnosis” agree 0 20 40 60 80 100 No one else but HCP Other Esthetician Other with SD or similar condition Nutritionist Friends Hairstylist/Barber Family member Patients (%) 45% 25% 22% 19% 19% 14% 5% 24% 0 20 40 60 80 100 None of these Worried about safety of treatments prescribed Treatment options were too expensive Lack of prescription treatment options that worked Insurance coverage for treatments was too difficult to navigate Ability to manage symptoms without prescription treatments Improvement in symptoms Patients (%) 50% 24% 20% 16% 13% 5% 13% Patient is actively meeting with HCP to manage SD REFERENCE 1. Dessinioti C, Katsambas A. Clin Dermatol 2013;31:343–351. ACKNOWLEDGEMENTS • This study was supported by Arcutis Biotherapeutics, Inc. • Thank you to the investigators and their staff for their participation in the trial • We are grateful to the study participants and their families for their time and commitment • Writing support was provided by Lauren Ramsey, PharmD, Alligent Biopharm Consulting LLC, and funded by Arcutis Biotherapeutics, Inc. Sex Men: 55% Women: 45% Mean age 40 years old White: 52% Hispanic: 31% Black or African American: 12% Asian: 3% Race and Ethnicity Patient-Reported Severity HCP-Reported Severity Mild Moderate Severe 71% 16%13% 19% 40% 41% Sex Men: 41% Women: 59% Mean years of practice Dermatologist: 3.3 years NP/PA: 2.9 years Mean number of patients seen in a typical WEEK 157.7 patients Mean number of patients with SD seen per YEAR 323.7 patients HCPs Patients 0 1 2 3 4 Ye ar s Fr om S ym pt om O ns et t o D ia gn os is HCPs Patients 1.5 3.6 Patient-reported severity in those who sought treatment <1 year after symptom onset Mild Moderate Severe 0 20 40 60 80 100 Pa ti en ts (% ) 31% 20% 66% 85% 15% 85% Yes No • Before visiting an HCP for SD symptoms, patients said family members (45%), hair stylists/barbers (25%), and friends (22%) helped them identify SD as the cause of their symptoms (Figure 6) • Among these patients (n=223), 48% said conversations with non-HCPs made them feel better. Figure 5. Patient- and HCP-Reported Initial Patient Perceptions of SD Prior to Diagnosis HCP: healthcare provider; SD: seborrheic dermatitis. “I didn’t think my symptoms were severe enough to warrant medical attention” “Most did not think that SD symptoms warranted medical attention” 63% Patients agree 66% HCPs agree “I was embarrassed to talk to my family or friends about my symptoms” “Most were embarrassed to talk to their family or friends about their symptoms” 59% Patients agree 65% HCPs agree “I was embarrassed to talk to my HCP about my symptoms” “Most were embarrassed to talk to me about their symptoms” 58% Patients agree 32% HCPs agree Patient and Healthcare Provider Perspectives on the Path to Diagnosis of Seborrheic Dermatitis: Results From a National Survey of Adults With Seborrheic Dermatitis in the United States << /ASCII85EncodePages false /AllowTransparency false /AutoPositionEPSFiles true /AutoRotatePages /None /Binding /Left /CalGrayProfile (Dot Gain 20%) /CalRGBProfile (sRGB IEC61966-2.1) /CalCMYKProfile (U.S. Web Coated \050SWOP\051 v2) /sRGBProfile (sRGB IEC61966-2.1) /CannotEmbedFontPolicy /Warning /CompatibilityLevel 1.3 /CompressObjects /Off /CompressPages false /ConvertImagesToIndexed true /PassThroughJPEGImages true /CreateJobTicket false /DefaultRenderingIntent /Default /DetectBlends true /DetectCurves 0.0000 /ColorConversionStrategy /sRGB /DoThumbnails false /EmbedAllFonts true /EmbedOpenType false /ParseICCProfilesInComments true /EmbedJobOptions true /DSCReportingLevel 0 /EmitDSCWarnings false /EndPage -1 /ImageMemory 1048576 /LockDistillerParams false /MaxSubsetPct 100 /Optimize true /OPM 1 /ParseDSCComments true /ParseDSCCommentsForDocInfo true /PreserveCopyPage true /PreserveDICMYKValues true /PreserveEPSInfo true /PreserveFlatness false /PreserveHalftoneInfo false /PreserveOPIComments false /PreserveOverprintSettings true /StartPage 1 /SubsetFonts true /TransferFunctionInfo /Apply /UCRandBGInfo /Remove /UsePrologue false /ColorSettingsFile () /AlwaysEmbed [ true ] /NeverEmbed [ true ] /AntiAliasColorImages false /CropColorImages false /ColorImageMinResolution 300 /ColorImageMinResolutionPolicy /OK /DownsampleColorImages true /ColorImageDownsampleType /Bicubic /ColorImageResolution 600 /ColorImageDepth -1 /ColorImageMinDownsampleDepth 1 /ColorImageDownsampleThreshold 1.00000 /EncodeColorImages true /ColorImageFilter /DCTEncode /AutoFilterColorImages true /ColorImageAutoFilterStrategy /JPEG /ColorACSImageDict << /QFactor 0.15 /HSamples [1 1 1 1] /VSamples [1 1 1 1] >> /ColorImageDict << /QFactor 0.15 /HSamples [1 1 1 1] /VSamples [1 1 1 1] >> /JPEG2000ColorACSImageDict << /TileWidth 256 /TileHeight 256 /Quality 30 >> /JPEG2000ColorImageDict << /TileWidth 256 /TileHeight 256 /Quality 30 >> /AntiAliasGrayImages false /CropGrayImages false /GrayImageMinResolution 300 /GrayImageMinResolutionPolicy /OK /DownsampleGrayImages true /GrayImageDownsampleType /Bicubic /GrayImageResolution 450 /GrayImageDepth -1 /GrayImageMinDownsampleDepth 2 /GrayImageDownsampleThreshold 1.00000 /EncodeGrayImages true /GrayImageFilter /DCTEncode /AutoFilterGrayImages true /GrayImageAutoFilterStrategy /JPEG /GrayACSImageDict << /QFactor 0.15 /HSamples [1 1 1 1] /VSamples [1 1 1 1] >> /GrayImageDict << /QFactor 0.15 /HSamples [1 1 1 1] /VSamples [1 1 1 1] >> /JPEG2000GrayACSImageDict << /TileWidth 256 /TileHeight 256 /Quality 30 >> /JPEG2000GrayImageDict << /TileWidth 256 /TileHeight 256 /Quality 30 >> /AntiAliasMonoImages false /CropMonoImages false /MonoImageMinResolution 1200 /MonoImageMinResolutionPolicy /OK /DownsampleMonoImages true /MonoImageDownsampleType /Bicubic /MonoImageResolution 600 /MonoImageDepth -1 /MonoImageDownsampleThreshold 1.00000 /EncodeMonoImages true /MonoImageFilter /CCITTFaxEncode /MonoImageDict << /K -1 >> /AllowPSXObjects false /CheckCompliance [ /None ] /PDFX1aCheck false /PDFX3Check false /PDFXCompliantPDFOnly true /PDFXNoTrimBoxError false /PDFXTrimBoxToMediaBoxOffset [ 0.00000 0.00000 0.00000 0.00000 ] /PDFXSetBleedBoxToMediaBox false /PDFXBleedBoxToTrimBoxOffset [ 0.00000 0.00000 0.00000 0.00000 ] /PDFXOutputIntentProfile (U.S. Web Coated \050SWOP\051 v2) /PDFXOutputConditionIdentifier (CGATS TR 001) /PDFXOutputCondition () /PDFXRegistryName (http://www.color.org) /PDFXTrapped /False /CreateJDFFile false /Description << /ENU ([Based on 'EPG UPLOAD'] [Based on 'EPG UPLOAD'] [Based on 'HighResolution_NoCrops'] [Based on 'HighResolution_NoCrops'] [Based on 'HighResolution_NoCrops\\0501\\051'] [Based on 'HighResolution_WithCrops'] [Based on '[PDF/X-1a:2001]'] Use these settings to create Adobe PDF documents that are to be checked or must conform to PDF/X-1a:2001, an ISO standard for graphic content exchange. 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