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RESEARCH ARTICLE ABSTRACTS

South African Family Practice is co-published by Medpharm Publications, NISC (Pty) Ltd and Taylor & Francis, and Informa business

S Afr Fam Pract
ISSN 2078-6190  EISSN 2078-6204

© 2016  The Author(s)

RESEARCH

South African Family Practice 2016; 58(4):148–152
http://dx.doi.org/10.1080/20786190.2016.1151643

Open Access article distributed under the terms of the
Creative Commons License [CC BY-NC 3.0]
http://creativecommons.org/licenses/by-nc/3.0

More than scales and tape measures needed to address obesity in South Africa
R Ramlala and RD Govendera*

a Department of Family Medicine, University of KwaZulu-Natal, Durban, South Africa
*Corresponding author, email: Govenderr1@ukzn.ac.za

Obesity is an emerging public health problem worldwide increasing from 857 million in 1980 to 2.1 billion by 2013. A study was 
done on a sample of 100 obese and overweight patients with a body mass index (BMI) above 25 kg/m2. The patients were asked 
to complete a questionnaire, which included socio-demographic data and perceptions regarding their weight.
The patients were between the ages of 18 and 76  years old with 82% being female patients. The mean BMI for males was  
41.7 kg/m2 (SD = 7.38112) and females 39.9 kg/m2 (SD = 7.90504). The results of this study confirm that 17% of overweight and 
obese patients saw themselves as having a normal weight and 97% felt that they were not unattractive. Of the sample, 96% 
affirmed that being obese was a health risk. The commonest reason cited for their obesity is by choice (70%).
Although obese patients knew that obesity is a health risk, they have a positive image of obesity. The dramatic trend towards 
increasing obesity suggest that healthcare providers need to understand how people from different cultures view obesity. This 
will help them to promote key messages about the health risks associated with excess weight in a culturally sensitive way.

Keywords: obesity, overweight, perceptions, South Africa

Introduction
Worldwide obesity has more than doubled since 1980.1 By 2014, 
more than 1.9 billion adults, aged 18  years and older, were 
overweight and of these over 600 million were obese.1 
Overweight and obesity are defined as abnormal or excessive fat 
accumulation in adipose tissue. The body mass index (BMI) is a 
simple index of weight-to-height that is commonly used to 
classify overweight and obesity in adults. It is defined as a 
person’s weight in kg divided by the square of their height in 
meters (kg/m2). The WHO defines a BMI of  >  25  kg/m2 as 
overweight and a BMI  >  30  kg/m2 as obese. Globally the 
proportion of adults with a BMI > 25  kg/m2 increased between 
the years 1980 and 2013 from 28.8% to 36.9% in men and from 
29.8% to 38% in women.2 In South Africa 7 in 10 women (69.3%) 
and 4 in 10 men (38.8%) are overweight or obese. South African 
children are showing a similar pattern with 7% of boys and 9.6% 
of girls classified as obese.2

Almost half the population in developed countries is obese.3 This 
is particularly prevalent in countries where a sedentary lifestyle 
together with an increased consumption of energy-rich, high-fat 
and high carbohydrate foods has resulted in obesity.3 However, 
the rates vary widely throughout the world with more than half 
of the world’s 671 million obese individuals living in just 10 
countries: the USA, China, India, Russia, Brazil, Mexico, Egypt, 
Germany, Pakistan, and Indonesia.2 Developing countries, 
particularly those undergoing an epidemiological transition 
similar to South Africa, also show an increase in the prevalence of 
obesity4–6 with the overall prevalence in South Africa being 
higher than in most other African countries.7 The prevalence in 
South Africa is 29% of men and 56% of women are classified as 
overweight or obese. Of these obese women, 30% are aged 
between 30 and 59 years.2 Recent South African studies show a 
change in prevalence associated with ethnicity and age.8 Central 
obesity was found in 42.2% of women and was most prevalent in 
urban Black African and women of mixed ancestry whereas only 
9.2% of the men had central obesity with older and white males 
having the highest prevalence.8

Overweight and obesity is a major contributor to the global 
burden of non-communicable diseases (NCDs) and the 
associated morbidity and mortality.9 In common with other 
African countries, South Africa (SA) is currently encountering an 
increasing burden of NCDs associated with overweight and 
obesity.10 In SA the burden of disease attributed to obesity is 87% 
for type 2 diabetes, 68% for hypertensive disease, 61% for 
endometrial cancer and 24% for osteoarthritis.11

Determinants of the obesity epidemic are complex and therefore 
patients’ perceptions regarding a preferred body image are 
important to help educate the patient regarding the association 
of obesity with the morbidity or mortality related to NCDs.12,13 In 
SA, in addition to the usual contributory factors for obesity in 
women, the perceptions of black women preferring a larger 
body size constitute an important additional factor.14 Being 
overweight is culturally acceptable and is seen as a sign of 
economic prosperity and a happy marriage.11 Perceptions not 
only reflect people’s views and thoughts but are ideas that exist 
in the minds of people about how they are viewed by others.15 
This influences their actions, behaviour and lifestyles and has 
been documented as a barrier to weight loss.15 In a recent study, 
participants associated thinness with being afflicted by HIV.8 In 
an exploratory study conducted on black women attending the 
NCD outpatient clinic at a hospital in Durban, South Africa, it was 
shown that the women underestimated their actual weight and 
perceived themselves to be thinner.16 This is one of the barriers to 
patients losing weight.13,16 Thus this study aimed to describe 
perceptions of weight in overweight and obese patients in order 
to assess whether a weight loss programme was implementable 
in these two groups of people.

Methodology
Design
This was a descriptive, observational study conducted in a 
sample of 100 overweight or obese patients, i.e. with a 
BMI  >  25  kg/m2 in a private general practice situated in a peri-
urban area north of Durban. The demographic profile of the 

South African Family Practice is co-published by Medpharm Publications, NISC (Pty) Ltd and Taylor & Francis, and Informa business

S Afr Fam Pract
ISSN 2078-6190  EISSN 2078-6204

© 2016  The Author(s)

  RESEARCH

South African Family Practice 2016; 58(4):142–147
http://dx.doi.org/10.1080/20786190.2016.1148337

Open Access article distributed under the terms of the
Creative Commons License [CC BY-NC 3.0]
http://creativecommons.org/licenses/by-nc/3.0

Anti-epileptic prescribing patterns in the South African private health sector 
(2008–2013)
Karen Jacobsa, Marlene Julyana , Martie S Lubbea, Johanita R Burgera* and Marike Cockerana

a Medicine Usage in South Africa, Faculty of Health Sciences, North-West University, Potchefstroom Campus, Potchefstroom, South Africa
*Corresponding author, Email: Johanita.Burger@nwu.ac.za

Background: Little is known about longitudinal prescribing practices for anti-epileptic drugs (AEDs) in South Africa. The 
prescribing patterns and associated direct medicine costs of AEDs in the private health sector were investigated, using claims 
data from January 1, 2008 to December 31, 2013.
Methods: The annual prevalence of prescriptions, AEDs and AED generics per patient with epilepsy (ICD-10 code G40) was 
determined. Cost analyses conducted included the calculation of the total direct cost of AEDs (medical scheme contribution, 
patient co-payment, and single exit price (SEP)), and the average cost per AED per year.
Results: Prevalence of patients claiming anti-epileptics ranged between 0.87% and 0.91% from 2008 to 2013. AED prescriptions/
patient ranged from 11.76 (95% CI, 11.56–11.95)] in 2008 to 11.90 (95% CI, 11.71–12.09) in 2013. Patients aged 40–65 years had 
the highest number of AED prescriptions/year. Valproate was most prescribed, followed by lamotrigine and carbamazepine. 
Average cost per AED increased from R237.12 (95% CI, 233.58–240.65) in 2008 to R522.32 (95% CI, 515.24–529.41) in 2013, while 
the average patient co-payments increased from R27.76 (95% CI, 26.63–28.89) to R264.32 (95% CI, 260.61–268.03). Prescribing of 
generics increased by 12.84%.
Conclusions: Generic prescribing increased over time; however, patient co-payments increased dramatically.

Keywords: anti-epileptic, direct medicine costs, longitudinal, medicine claims database, prescribing patterns, South Africa

Introduction
Approximately 50 million people worldwide suffer from 
epilepsy.1 Based on a meta-analysis by Ngugi and colleagues,2 
the median prevalence of lifetime epilepsy is 5.8 per 1  000 in 
developed countries, 10.3 per 1  000 in lower-income or 
developing countries and 15.4 per 1000 in rural areas of 
developing countries. Prevalence studies conducted in South 
Africa have reported a lifetime prevalence of 7.3 per 1  000 in 
children of a rural district and an estimated prevalence of 7.0 per 
1 000 in a rural north-east district, respectively.3,4

Anti-epileptic drugs (AEDs) are increasingly being prescribed to 
patients of all ages in populations worldwide,5,6 either as 
monotherapy or polytherapy.7 Although AEDs are primarily 
prescribed for epileptic seizures, they are also used for other co-
morbidities, such as neuropathic pain, particularly diabetic 
neuropathy and postherpetic neuralgia, migraine prophylaxis 
and bipolar disorder.8,9 The prescribing of first-choice AEDs in 
particular has changed over the last decade,10 with prescribers 
tending to prescribe newer AEDs (e.g. gabapentin, lamotrigine, 
levetiracetam and pregabalin) to patients due to their improved 
tolerability.11

Anti-epileptic drugs, in particular those that are still under patent 
such as some of the newer AEDs, are relatively expensive.12–14 
Generic substitution of many drug classes is a common health 
care cost-saving practice;15 however, use of generic antiepileptic 
drugs in patients with epilepsy is controversial.16

Little is known about the longitudinal prescribing practices for 
anti-epileptic drugs (AEDs) in South Africa. The aim of this study 
was therefore firstly to investigate the prescribing patterns of 

AEDs in the private health sector of South Africa and secondly to 
determine the total direct cost of anti-epileptic treatment during 
the study period.

Methods
Study design
A quantitative, retrospective drug utilisation review was 
conducted using nationally representative medicine claims data 
for a six-year period (January 1, 2008 to December 31, 2013). 
Data were obtained from a privately owned South African 
Pharmaceutical Benefit Management (PBM) company. The PBM 
currently manages the medicine benefits of 1.7 million 
beneficiaries on behalf of 40 medical schemes. All of South 
Africa’s pharmacies and 98% of all dispensing doctors are on this 
service provider database. Data for 758 505 patients from 2008 
were obtained, compared with 1  033  057 from 2009, 968  158 
from 2010, 864 977 from 2011, 815 810 from 2012, and 809 857 
from 2013. In 2008 these patients represented 9.6% of all 
beneficiaries covered by medical aid schemes registered in terms 
of the Medical Schemes Act (Act 131/1998) in South Africa, 
compared with 13% in 2009, 11.7% in 2010, 10.3% in 2011, 9.5% 
in 2012, and 9.3% in 2013.17

Data fields used in this study included the following: patients’ 
member number, patients’ date of birth, treatment date, ICD-10 
codes, active ingredients, the quantity of medicine items 
prescribed and the number of days for which the medicine items 
were supplied.

Study population
The study population consisted of all patients with an ICD-10 
code for epilepsy (G40) as recorded on the database, in 

S Afr Fam Pract 2016; DOI:10.1080/20786190.2016.1148337

S Afr Fam Pract 2016; DOI:10.1080/20786190.2016.1151643

Abstract (Full text available online at www.tandfonline.com/ojfp)

Abstract (Full text available online at www.tandfonline.com/ojfp)