QUIZ CASE

SA JOURNAL OF RADIOLOGY  •  September 2011     101

Paediatric neuropathology
S K Misser, MB ChB, FCRad (D)
Lake Smit and Partners, Durban

J F Roos, MB ChB, MMed (Paed)
Parklands Hospital, Durban

Corresponding author: S Misser (shalendramisser@hotmail.com)

Presentation
A 10-month-old child presented with spasticity, regression of milestones 
and irritability. The following images were obtained (Figs 1 - 5). Non-
specific EEG abnormality was also documented.

Describe the relevant findings and provide the most appropriate 
clinical diagnosis. Please submit your response to shalendramisser@
hotmail.com not later than 1 November 2011. The winning respondent 
will receive a R1 000 award from the RSSA. A detailed diagnosis and 
discussion will be presented in the next issue of the SAJR.

1 2 3

Fig. 3 is an axial inversion recovery sequence.

4a 4b

Figs 4a and 4b are axial pre- and post-gadolinium sequences respectively.

5a 5b

Figs 5a and 5b are axial pre- and post-gadolinium sequences respectively.

Figs 1 and 2 are axial T2-w MRI sequences.