SEEHSJ - South Eastern Europe Health Sciences Journal SOUTHEASTERN EUROPEAN MEDICAL JOURNAL SEEMEDJ FACULTY OF MEDICINE OSIJEK Josip Juraj Strossmayer University of Osijek J. Huttlera 4 Croatia – 31000 Osijek seemedj@mefos.unios.hr seemedj.mefos.unios.hr Editorial SEEMEDJ 2022;6(2): 1-85 Dear colleagues, Hereby, new 12th issue of SEEMEDJ is presented to you. This issue brings 7 articles with various topics. The molecular dynamics of the antigen-antibody reaction and the role of water molecules is presented in the article by Nemeth P. Iskandarov et al investigated bioactive components that affect blood coagulation system by fractionation of Vipera berus berus snake venom which may be utilized in biotechnology and medicine. Microcirculatory blood flow after acute exertional exercise was examined by Potočnik N. TFF3 is involved in the pathogenesis of sepsis, but the exact mechanism is not yet clear. This issue has been reviewed by Bazina and Baus Lončar. Comorbidities of psychiatric and somatic disease pose a major challenge to modern medicine and the multidisciplinary approach and cooperation in treatment are necessary to improve the patients’ quality of life and life expectancy, as presented in a work by Marušić R et al. Vidović et al detected vitamin D deficiency in a population of medical students, which is significant problem noted elsewhere also. And finally, Krajina Kmoniček et al reviewed the effects of iron chelators in COVID-19 disease. We are happy to inform our potential authors that SEEMEDJ has been included to another citation bases: Crossref, Dimensions and Publons, thus widening our accessibility to readers. The art work at the cover page is authored by Nevenka Arbanas, Croatian graphic artist born in Batina, Baranja. This way, we continue to present our national but widely recognized artists with the origin from Easter Slavonia and Baranja. I hope that readers will find relevant published articles for their work. On the behalf of the editorial board and my own, I warmly greet our readers and invite them to join us in the endeavor of publishing their own scientific work in SEEMEDJ. Ines Drenjančević, MD, PhD Editor-in-Chief Southeastern European Medical Journal (SEEMEDJ)