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BOOK REVIEW
Written by two dermatologists from the University of
KwaZulu-Natal’s Nelson R Mandela School of Medicine, the
much-needed 2nd edition of the Atlas of Skin Conditions in HIV/AIDS
is now available. Immunocompromise in HIV cases results in a large
variety of skin findings that significantly differ in quality and
extent from those in immunocompetent people.
Acknowledging the fact that dermatological problems are often a
challenge to clinicians, this is an important area demanding an
easy-to-use atlas to identify the most common diseases. As HIV
treatment increasingly becomes a condition to be treated at a general
primary health care level, this becomes even more pertinent.
To meet the needs of the clinician, the atlas is put together in a
way that makes it a pleasure to use quick reference for clinical
findings. The book’s chapters are structured by type of skin
eruption rather than nosological disease entity, which adds to the ease
with which a specific clinical presentation can be found. These groups
of skin conditions are ‘Blisters’, ‘Papulosquamous
conditions’, Papules and nodules’, ‘Ulcers’,
‘Nails’, ‘Oral lesions’,
‘Miscellaneous’ and ‘Antiretroviral therapy’.
Only the chapter on ‘Antiretroviral therapy’ attempts a
more systemic approach, based on the causation rather than the clinical
presentation, when it lists a range of conditions that might erupt
under antiretroviral treatment. These conditions are presented in the
two sections ‘Immune reconstitution inflammatory syndrome’
(IRIS) and ‘Cutaneous manifestations of antiretroviral
drugs’.
For each condition, on the left page there are high-quality colour
pictures displaying the skin condition. This is complemented by a brief
description of the condition and its treatment on the opposite page.
This includes a hands-on treatment recommendation with standard dosages
and durations for the treatment and explicitly including both EDL
(Essential Drugs List for primary health care) and non-EDL items.
With its user-friendly structure, this atlas is a valuable addition
to the standard reference in a consultation room in public sector
facilities. It is comprehensive enough to include the more common
conditions, while at the same time concise enough to serve as a quick
reference during or in between consultations. On the wish-list for
future editions would be an update of the primary health care EDL
reference, as the book refers to the 1998 edition of this list. Having
been published before the new antiretroviral treatment guidelines came
into effect in 2010, a future edition should possibly also present
clinical examples of the skin presentation of the abacavir
hypersensitivity syndrome (which is only mentioned in the text), as
this drug is now part of the paediatric first-line regimen and skin
eruptions following the initiation of this drug are a major point of
concern. Similarly, tenofovir, which is now part of the adult
first-line regimen, is not mentioned in the book but would probably
have shown its dermatological side-effects (if any) by the time the
next edition appears.
Dirk Hagemeister
Paarl
A Clinical Atlas of Skin Conditions in HIV/AIDS: An Illustrated Management Guide for Health Care Professionals. By Ncoza Dlova and Anisa Mosam.
2nd ed. Pretoria: HPMG, 2009. Pp. 100. ISBN 1-875098-40-2.