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Sugammadex: A neuromuscular blockade agent encapsulator

Victoria Yepes Hurtado BSN, RN

ABSTRACT

Sugammadex sodium, a modified γ-cyclodextrin, represents a new class of drugs effective at reversing non-depolarizing muscle relaxants rocuronium and vecuronium. The cylindrical, basket-like structure encapsulates neuromuscular blocking agents which results in rapid reversal of paralysis within three minutes. The current literature was reviewed to analyze the clinical implications and considerations with its administration.

Keywords: cyclodextrin, encapsulation, selective relaxant binding agent, sugammadex, supramolecular




Article citation: Yepes Hurtado V. Sugammadex: a neuromuscular blockade agent encapsulator. The Southwest Respiratory and Critical Care Chronicles 2017;5(20):44-49.

From: University Medical Center, Lubbock, TX.

Submitted: 4/30/2017

Accepted: 7/4/2017

Reviewer: John Wasnick MD

Conflicts of interest: none