Case series and focused review


Wild transthyretin amyloid cardiomyopathy recognition with noninvasive strategies: A case report and diagnostic approach for transthyretin-related cardiomyopathy

Gaspar Del Rio-Pertuz MD, Leigh Ann Jenkins MD, Pooja Sethi MD, Erwin Argueta-Sosa MD

ABSTRACT

Recent studies suggest that the prevalence of wild type transthyretin cardiomyopathy (wATTR-CM) is substantially higher than previously appreciated in older adults with heart failure. Advances in nuclear imaging using bone avid radiotracers permit diagnosis of transthyretin-related cardiomyopathy (ATTR-CM) without a tissue biopsy. We describe two wATTR-CM cases that were diagnosed using noninvasive methods and demonstrate this diagnostic approach for transthyretin-related cardiomyopathy.

Keywords: amyloid, cardiomyopathy




Article citation: Del Rio-Pertuz G, Jenkins LA, Sethi P, Argueta-Sosa E. Wild transthyretin amyloid cardiomyopathy recognition with noninvasive strategies: A case report and diagnostic approach for transthyretin-related cardiomyopathy. The Southwest Respiratory and Critical Care Chronicles 2022;10(42):16–21

From: Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas

Submitted: 12/13/2021

Accepted: 1/10/2022

Conflicts of interest: none

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