Sultan Qaboos University Med J, August 2015, Vol. 15, Iss. 3, pp. e438–439, Epub. 24 Aug 15. doi: 10.18295/squmj.2015.15.03.023.
Submitted 25 Nov 14
Revision Req. 21 Jan 15; Revision Recd. 29 Jan 15
Accepted 19 Feb 15

Departments of 1Child Health, 2Surgery and 3Radiology & Molecular Imaging, Sultan Qaboos University Hospital, Muscat, Oman
*Corresponding Author e-mail: koul@squ.edu.om and roshankoul@hotmail.com

نوبات األمل األذين االنتيايب يف الشريان املخيخي األمامي السفلي يف طفل
رو�سان كول، رانا عبد الرحيم، راجيف كاريياتيل، ديليب �سانخال

Anterior Inferior Cerebellar Artery Loop-Induced 
Paroxysmal Otalgia in a Child
*Roshan Koul,1 Rana A. Rahim,1 Rajeev Kariyattil,2 Dilip Sankhla3

 
Figure 1: Time-of-flight magnetic resonance angiography image in the axial plane showing an anterior inferior cerebellar 
artery loop in the left internal auditory meatus (arrow) of a seven-year-old girl with paroxysmal otalgia.  

interesting medical image 

A seven-year-old girl was referred to the child neurology outpatient clinic of Sultan Qaboos University Hospital in Muscat, 
Oman, in June 2014 by an ear, nose and throat (ENT) 
specialist from another hospital for an evaluation of 
pain in her left ear. The pain had started about two 
and half years previously and was paroxysmal and 
associated with decreased hearing and tinnitus. The 
pain typically lasted two to three hours at a time. 
Initially, the child was only in pain once per month; 
however, more recently, the frequency had increased 

to two to three times a day. During episodes of otalgia, 
the pain was so severe that the girl could do nothing 
but cry out for help to relieve it. In between these 
episodes, there were no signs of tinnitus or hearing 
loss. There were no apparent triggers for the pain, such 
as swallowing or being touched on the face. 

The child had previously undergone routine ENT 
examinations at two clinics. A computed tomography 
scan of the brain was performed to identify temporal 
bone and internal auditory canal lesions, which revealed 
no abnormalities. A hearing test, tympanometry and 



Roshan Koul, Rana A. Rahim, Rajeev Kariyattil and Dilip Sankhla

Interesting Medical Image | e439

triggers pain due to the intermediate nerve, while pain 
when swallowing is due to the ninth nerve. However, 
no such triggers were observed for the current patient. 
An MRI scan revealed that an arterial loop of the AICA 
was compressing the seventh nerve. Neurosurgical 
decompression is the definitive treatment for this 
condition.2 This type of pain must be differentiated 
from that caused by a migraine; this can be difficult 
in younger patients as they may not be able to explain 
their pain clearly. For the current patient, the pain 
began when she was four and a half years old. There 
was an improvement in the severity of the pain after 
taking gabapentin. Other causes for recurrent facial 
pain need to be investigated thoroughly to rule out 
dental and ophthalmic conditions. Rarely, trigeminal 
neuralgia may present in a similar way.3 Clinicians 
should therefore always attempt to determine the 
underlying cause of unexplained headaches or facial 
pain in children.

References
1. Smith JH, Robertson CE, Garza I, Cutrer FM. Triggerless 

neuralgic otalgia: A case series and systematic literature review. 
Cephalalgia 2013; 33:914–23. doi: 10.1177/0333102413477743.

2. Younes WM, Capelle HH, Krauss JK. Microvascular 
decompression of the anterior inferior cerebellar artery for 
intermediate nerve neuralgia. Stereotact Funct Neurosurg 
2010; 88:193–5. doi: 10.1159/000313873.

3. Koul R, Alfutaisi A, Jain R, Alzri F. Trigeminal neuralgia due to 
anterior inferior cerebellar artery loop: A case report. J Child 
Neurol 2009; 24:989–90. doi: 10.1177/0883073809332403.

neurological examination were normal. A routine 
magnetic resonance imaging (MRI) of the brain was 
reported to show no abnormalities. However, based 
on the patient’s history and the normal ENT work-
up, the MRI was reviewed with the radiologist. On 
reassessment, an arterial loop of the anterior inferior 
cerebellar artery (AICA) was observed on the left side 
over the seventh cranial nerve in the internal auditory 
canal [Figure 1]. The ear pain was likely caused by 
pressure on the intermediate nerve, a branch of the 
seventh cranial nerve. 

The child was referred to a neurosurgeon for 
consultation and potential decompression. She was 
also started on gabapentin. This was prescribed 
initially as a nightly dose of 25 mg which was increased 
twice weekly to a maximum nightly dose of 100 mg. 
Conservative management (500 mg of paracetamol) 
was recommended for relief of the frequency and 
severity of her ear pain. A follow-up examination 
indicated an improvement of approximately 50% in 
the level of pain.

Comment

Otalgia is uncommon in children and is mainly seen 
in the sixth and seventh decades of life.1 There are 
several mechanisms which can result in ear pain, 
including lesions of the fifth, seventh, ninth, tenth and 
auricular temporal nerves.1 Pain of the inner ear and 
tympanic membrane is due specifically to lesions of 
the seventh (intermediate) and ninth nerves. These 
two types of lesions can be differentiated clinically 
by their causative factors. Touching the ear or face 

http://dx.doi.org/10.1177/0333102413477743
http://dx.doi.org/10.1159/000313873
http://dx.doi.org/10.1177/0883073809332403