# bib

id: translation-658
author: Devanaboyina, Monika
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 343
sentence: 16
flesch: 53
cache: cache/translation-658.pdf
txt: txt/translation-658.txt
title:
  Analysis of Demographic and Staging Characteristics in Patients with Colorectal Cancer Using the SEER Registry

summary:
  The incidence of CRC increased with age where ages 75+ had the highest incidence at 211.8 per 100,000, compared to 70.7 for ages 50-64. Of note, Asian females aged 50-64, Hispanic females ages 65 and older, and Black and White females ages 75+ were equally likely to present with local or regional disease.


id: translation-742
author: Rehman, Naveen
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 326
sentence: 12
flesch: 30
cache: cache/translation-742.pdf
txt: txt/translation-742.txt
title:
  A patient with Factor V Leiden mutation who developed a Pulmonary Embolism and Deep Vein Thrombosis post Covid

summary:
  Case Presentation: A 53-year-old male with a past medical history of Factor V Leiden mutation on warfarin, atrial fibrillation, and Covid pneumonia complicated by hypoxic respiratory failure 6 weeks ago presented to the emergency department at the University of Toledo with a chief complaint of bilateral arm pain of 2 days duration, along with redness and swelling of his arms. Current literature outlines the incidence of Covid coagulopathy in patients without a previous history of hypercoagulability, however few sources have examined the consequences of Covid coagulopathy in patients with existing prothrombotic states.


id: translation-759
author: Soewarna, Victoria
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 332
sentence: 20
flesch: 28
cache: cache/translation-759.pdf
txt: txt/translation-759.txt
title:
  Cellulosimicrobium Bacteremia in a Patient With Small Cell Lung Cancer: : Emergence of a New Gram-Positive Branching Rod

summary:
  The blood cultures were identified as Cellulosimicrobium species on hospital day 11; his meropenem was discontinued and vancomycin was initiated. His neutropenia recovered on hospital day 2, but his fevers persisted and were attributed to pneumonia and possible bacteremia.


id: translation-748
author: Issa, Rochell
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 298
sentence: 13
flesch: 42
cache: cache/translation-748.pdf
txt: txt/translation-748.txt
title:
  Urban-rural Disparities in Trends of Pulmonary Hypertension-Related Mortality in the United States, 2004-2019

summary:
  Rural counties had an overall significantly higher AAMR than urban counties, (rural: 10.75 Conclusion: Overall, our results indicate a gap in PH-associated healthcare services among those living in rural counties as compared to those living in urban counties within the US.


id: translation-665
author: Farrow, David
title: Use of Endoscopic Vacuum Therapy to Repair Colonic Anastomotic Leaks: : A Meta Analysis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 348
sentence: 19
flesch: 47
cache: cache/translation-665.pdf
txt: txt/translation-665.txt
summary:
  Endoscopic vacuum therapy (EVT) has recently emerged as a treatment modality for patients who experience anastomotic leak after surgery with an incidence of 6-30%. Treatment of anastomotic leaks using EVT in the upper gastrointestinal tract has been well documented.


id: translation-650
author: Prevoznik, Stephen
title: Glucocorticoid-induced Stress Mechanism in Mouse Primary Neurons
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 341
sentence: 19
flesch: 56
cache: cache/translation-650.pdf
txt: txt/translation-650.txt
summary:
  One plate of cortex neurons was grown in an IncuCyte incubator to allow axon length to be continuously measured by NueroTrack software. This study aimed to examine whether inducing a depression-like state caused any changes in gene expression or axon length in cultured neurons.


id: translation-648
author: Yassine, Shereen G.
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 302
sentence: 11
flesch: 30
cache: cache/translation-648.pdf
txt: txt/translation-648.txt
title:
  Exposure to Nanoplastics Induces an Inflammatory Response in Healthy and Type 2 Diabetic Primary Human Proximal Tubular Epithelial Cells

summary:
  Conclusion: Our results suggest that NPs induce an inflammatory response in human PTECs, which may be enhanced in prevalent, pre-existing conditions, such as T2D, with important implications for human health that warrant further investigation. Methods: Healthy and T2D primary human PTECs were cultured in 96 well-plates and exposed to 0.026%, 0.052% w/v 0.05 µm monodisperse polystyrene microspheres (or vehicle) for 24 hours.


id: translation-744
author: Gangwani, Manesh K.
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 383
sentence: 15
flesch: 39
cache: cache/translation-744.pdf
txt: txt/translation-744.txt
title:
  Bleeding Risk with Dual Antiplatelet Therapy and Gastrostomy Tube Placement: : A Systematic Review and Network Meta-Analysis

summary:
  Methods: The following databases were searched: PubMed, Embase, Cochrane, and Web of Sciences to include comparative studies evaluating single antiplatelet (aspirin, clopidogrel), dual antiplatelet (DAPT, aspirin and clopidogrel), and no antiplatelet therapy. May 5; 11(1):e1-e2 Bleeding Risk with Dual Antiplatelet Therapy and Gastrostomy Tube Placement: A Systematic Review and Network Meta-Analysis Manesh Kumar Gangwani, MD1*, Muhammad Aziz, MD2, Abeer Aziz, MD1, Fnu Priyanka, MD1, Arti Patel, MD1, Umar Ghaffar, MD1, Simcha Weissman, MD1, Asif Mahmood, MD1, Wade Lee-Smith, MLS3, Toseef Javaid, MD1, Ali Nawras, MD2 Benjamin Hart, MD1 1Division of Hospital Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Gastroenterology and Hepatology, Department of Medicine, The University of Toledo, Toledo, OH 43614 3Department of University Libraries, The University of Toledo, Toledo, OH 43614


id: translation-654
author: Aziz, Muhammad
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 347
sentence: 16
flesch: 48
cache: cache/translation-654.pdf
txt: txt/translation-654.txt
title:
  Impact of Guidewire Caliber on ERCP Outcomes: Systematic Review and Meta-Analysis Comparing 0.025- and 0.035-Inch Guidewires

summary:
  The impact of guidewire caliber on endoscopic retrograde pancreatography (ERCP) outcomes are not clear. Other outcomes (overall cannulation rate, cholangitis, perforation, bleeding, use of adjunct techniques) were also comparable.


id: translation-755
author: Ibaraki, Makoto
title: Impact of a Dedicated Outpatient Parenteral Antibiotic Therapy Clinic on Patient Outcomes
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 324
sentence: 14
flesch: 31
cache: cache/translation-755.pdf
txt: txt/translation-755.txt
summary:
  Future studies will have to continue examining the association between OPAT clinic visits and readmission along with other predictors to further improve the outcomes of OPAT patients. Logistic regression was applied to determine the association between readmission and visit to OPAT clinics while also examining covariates including sex, comorbidities, pathogen, and planned length of therapy.


id: translation-757
author: Kammeyer, Joel
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 446
sentence: 20
flesch: 25
cache: cache/translation-757.pdf
txt: txt/translation-757.txt
title:
  Early Infectious Diseases Consultation and Procalcitonin-Guided Therapy Limits Unnecessary Antibiotic Use in COVID-19

summary:
  https://dx.doi.org/10.46570/utjms.vol11-2023-757 https://dx.doi.org/10.46570/utjms.vol11-2023-757 mailto:joel.kammeyer@utoledo.edu https://dx.doi.org/10.46570/utjms.vol11-2023-757 UTJMS 11(1):e1-e2 https://dx.doi.org/10.46570/utjms.vol11-2023-757 2 ©2023 UTJMS Conclusion: Early consultation of an ID specialist and evaluation of PCT levels leads to significant reductions in inappropriate antibiotic use. We report a significant reduction in antibiotic use among COVID-19 patients in the setting of near-universal ID consultation in COVID-19 patients.


id: translation-663
author: Farrow, David
title: Iron Deficiency Anemia Secondary to Colonic Diaphragm Disease
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 474
sentence: 20
flesch: 38
cache: cache/translation-663.pdf
txt: txt/translation-663.txt
summary:
  One uncommon complication of chronic NSAID use is the formation of diaphragm-like strictures, characterized by the circumferential narrowing of mucosal membranes. NSAID-induced colopathy was suspected to be the cause of anemia, for which she was counseled to discontinue NSAID use.


id: translation-791
author: Dworkin, Lance D.
title: Editorial
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 427
sentence: 18
flesch: 37
cache: cache/translation-791.pdf
txt: txt/translation-791.txt
summary:
  The opportunities I had as a trainee to listen and interact with leading investigators who came on campus are still some of my favorite memories from my entire academic career. Bringing outstanding investigators on campus helps to energize us and to remind us what can be accomplished through science to better understand our world and to advance medical therapeutics.


id: translation-278
author: Fatima, Rawish; Aziz, Muhammad; Khader, Yasmin; Lee-Smith, Wade; Altorok, Nezam
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 449
sentence: 22
flesch: 45
cache: cache/translation-278.pdf
txt: txt/translation-278.txt
title:
  Safety and Efficacy of Anifrolumab in Systemic Lupus Erythematosus: Systematic Review with Network Meta-analysis

summary:
  Secondary outcomes assessed included overall flares at 52 weeks, adverse events and serious adverse events. May 05; 11(1):e1-e2 Safety and Efficacy of Anifrolumab in Systemic Lupus Erythematosus: Systematic Review with Network Meta- analysis Rawish Fatima1*, Muhammad Aziz, MD2, Yasmin Khader3, Wade Lee-Smith4, Nezam Altorok, MD1 1Division of Rheumatology, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Gastroenterology, Diabetes, and Metabolism, Department of Medicine, The University of Toledo, Toledo, OH 43614 3Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 4Department of University Libraries, College of University Libraries, The University of Toledo, Toledo, OH 43614


id: translation-652
author: Aziz, Muhammad
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 395
sentence: 14
flesch: 31
cache: cache/translation-652.pdf
txt: txt/translation-652.txt
title:
  Comparison of Artificial Intelligence with other interventions to improve Adenoma Detection Rate for Colonoscopy: : A Network Meta-analysis

summary:
  Network meta-analysis demonstrated significantly improved ADR for AI compared to Autofluorescence imaging (RR: 1.33, CI: 1.06-1.66), dye-based chromoendoscopy (RR: 1.22, CI: 1.06-1.40), Endocap (RR: 1.32, CI: 1.17-1.50), Endocuff (RR: 1.19, CI: 1.04-1.35), Endocuff-Vision (RR: 1.26, CI: 1.13-1.41), Endoring (RR: 1.30, CI: 1.10-1.52), flexible spectral imaging color enhancement (RR: 1.26, CI: 1.09-1.46), Full-spectrum Endoscopy (RR: 1.40, CI: 1.19-1.65), High-Definition (RR: 1.41, CI: 1.28-1.54), Linked Color Imaging (RR: 1.21, CI: 1.08-1.36), Narrow Band Imaging (RR: 1.33, CI: 1.18-1.48), Water-Exchange (RR: 1.22, CI: 1.06-1.42), and Water- Immersion (RR: 1.47, CI: 1.19-1.82). Relative risk (RR) and 95% confidence interval (CI) were calculated for proportional outcome.


id: translation-746
author: Gangwani, Manesh
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 487
sentence: 21
flesch: 46
cache: cache/translation-746.pdf
txt: txt/translation-746.txt
title:
  Fresh vs Frozen vs Lyophilized Fecal Microbiota transplant for Recurrent Clostridium Difficile Infection: : A Systematic Review and Network Meta-analysis

summary:
  When compared to Fresh group, lower recovery rate was noted with both Frozen group (RD -0.06 95% CI -0.11-0.00, p=0.05) and Lyophilized group (RD -0.16 95% CI -0.27--0.05, p= 0.01). Fresh FMT was determined to be most successful with 93% efficacy 0.956 95 % CI (0.913 – 0.999) followed by Frozen with 88 % efficacy 0.902 95 % CI (0.857 – 0.947) and Lyophilized with 83% efficacy 0.828 95 % CI (0.745 – 0.910) .


id: translation-656
author: Aziz, Muhammad
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 402
sentence: 15
flesch: 38
cache: cache/translation-656.pdf
txt: txt/translation-656.txt
title:
  Lactated Ringer's Vs Normal Saline for Acute Pancreatitis: : An Updated Systematic Review and Meta-Analysis

summary:
  The overall ICU admission was lower in LR group compared to NS group (RR: 0.43, CI: 0.22-0.84). Subgroup analysis of RCTs demonstrated lower length of hospital stay for LR group compared to NS group (MD: 0.77 days, CI: 1.44 -0.09 days).


id: translation-200
author: Jankun, Jerzy; Redfern, Roberta; Sabharwal, Arjun
title: Editorial: what editors welcome
date: 2018-06-27
pages: 3
extension: .pdf
mime: application/pdf
words: 771
sentence: 39
flesch: 50
cache: cache/translation-200.pdf
txt: txt/translation-200.txt
summary:
  In the 20th century investment in medical sciences and public health resulted in an unprecedented improvement in the health and wellbeing of people. Translation; The University of Toledo Journal of Medical Sci-ences, online journal, launched a few years ago by UT, is accept- ing again papers in all aspects of medical sciences in four different categories: (i) original articles reporting results of basic or clinical research; (ii) case reports; (iii) reviews; (iv) and editorials.


id: translation-317
author: Lubarsky, Daniel
title: Streptococcus Pneumoniae Urinary Tract Infection in 3-Year-Old Girl
date: 2019-12-03
pages: 4
extension: .pdf
mime: application/pdf
words: 1708
sentence: 96
flesch: 47
cache: cache/translation-317.pdf
txt: txt/translation-317.txt
summary:
  While a common cause of upper respiratory infections, the current Infectious Diseases Society of America (IDSA) guidelines on urinary tract infections do not cite Streptococcus pneumoniae as a cause for UTIs in children (2). While a common cause of upper respiratory infections, the current Infectious Dis- eases Society of America (IDSA) guidelines on urinary tract infec- tions (UTIs) do not cite Streptococcus pneumoniae as a cause for UTIs in children.


id: translation-266
author: Garcher, Damian
date: 2019-06-10
pages: 4
extension: .pdf
mime: application/pdf
words: 1747
sentence: 115
flesch: 57
cache: cache/translation-266.pdf
txt: txt/translation-266.txt
title:
  Functional Castration from Blunt-force Trauma to Motorcycle Gas Tank from a Car-versus-motorcycle MVA

summary:
  First reported in 1818 as a crush injury from a wagon wheel, testicular trauma is now well-described in modern literature (2). Although in general a rare entity in blunt trauma situations, testicular trauma is often associ- ated with motorcycle collisions (3, 4).


id: translation-205
author: Perz, Sarah K.; Tenbrink, Patrick M; Haselhuhn, Gregory H.
date: 2018-06-27
pages: 4
extension: .pdf
mime: application/pdf
words: 2347
sentence: 130
flesch: 45
cache: cache/translation-205.pdf
txt: txt/translation-205.txt
title:
  Bladder Wall Calcification Following Transurethral Resection of Bladder Tumor and Intravesical Mitomycin C Instillation

summary:
  In rarely reported instances, the use of intravesical mitomycin C appears to have caused bladder wall calcification. In rarely reported instances, the use of intravesical mitomycin C ap- peared to cause bladder wall calcification (2-4).


id: translation-299
author: Fumo, David Eugene
title: Boondoggled: A Case Report of Arts and Crafts Gone Wrong
date: 2019-07-23
pages: 4
extension: .pdf
mime: application/pdf
words: 2192
sentence: 155
flesch: 54
cache: cache/translation-299.pdf
txt: txt/translation-299.txt
summary:
  For the urologist, it is critical to recognize the mental health is- sues portended by urethral foreign body insertion, and take the appropriate steps to address the underlying problem. For the urologist, it is critical to recognize the mental health issues portended by urethral foreign body insertion, and take the appropriate steps to address the underlying problem.


id: translation-659
author: Dhoop, Sudheer
title: Metastatic Renal Cell Carcinoma to the Descending Colon Presenting as Recurrent Hematochezia
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 234
sentence: 10
flesch: 32
cache: cache/translation-659.pdf
txt: txt/translation-659.txt
summary:
  Our case demonstrates that interval metastasis should always be on the differential for persistent GI bleeding in the setting of RCC and it highlights challenges in management of hematochezia related to colorectal metastasis of RCC. This report documents a case of an individual with solitary metastasis of RCC to the descending colon presenting with recurrent hematochezia.


id: translation-743
author: Aldhafeeri, Abdulaziz
title: Daptomycin Associated Rhabdomyolysis with Concurrent Use of Atorvastatin
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 333
sentence: 12
flesch: 29
cache: cache/translation-743.pdf
txt: txt/translation-743.txt
summary:
  Conclusion: Daptomycin associated rhabdomyolysis is a rare and concerning side effect that require prompt discontinuation of the antibiotic. May 5; 11(1):e1-e1 Daptomycin Associated Rhabdomyolysis with Concurrent Use of Atorvastatin Abdulaziz Aldhafeeri, MD1*, Abdulmajeed Alharbi, MD1, Caleb Spencer, MD1, Bopp Benjamin, MD1, Kirubel Zerihun, MD1, Amna Al-Tkrit MD1 1Division of Hospital Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614


id: translation-104
author: Shukla, Vipul; Asp, Alex; Saltzman, Barbara; Duggan, Joan
title: Survey of health care student attitudes towards transgender health care education
date: 2018-06-27
pages: 5
extension: .pdf
mime: application/pdf
words: 3245
sentence: 182
flesch: 50
cache: cache/translation-104.pdf
txt: txt/translation-104.txt
summary:
  Survey of health care student attitudes towards transgender health care education Vipul Shukla a, Susan Dundas a , Alex Asp a , Barbara Saltzman a , and Joan Duggan a 1 aUniversity of Toledo Health Science Campus, Toledo, OH 43614 Background: This study assessed health care trainees percep- tions of their education regarding transgender health care issues and personal and professional comfort level with the provision of transgender health care. Despite this pressing need, this survey showed that educational hours devoted to transgender health care and direct patient contact with transgender patients remain limited for health care students across professional schools.


id: translation-241
title: Civilian Social Support and Posttraumatic Stress Disorder Symptoms among National Guard Members
date: 2018-09-28
pages: 4
extension: .pdf
mime: application/pdf
words: 3691
sentence: 223
flesch: 51
cache: cache/translation-241.pdf
txt: txt/translation-241.txt
author:
  Wang, Xin; Prince, Laura; Rattan, Juhi; Swartz, Neal L.; Shukla, Vipul; Durham, Tory A.; Biehn, Tracey L.; Drue, Jennifer L.; Ramachandran, Gowri; Sutu, Christine; Benton, Amber J.; Luckoski, John L.; Ding, Andrew; Tamburrino, Marijo B.

summary:
  Unlike intensive studies in active duty military personnel, fewer studies have examined the role of social support in National Guard mem- bers, and civilian social support is rarely investigated in these limited studies. In addition to unit support, the influence of civilian social support was also considered a potent buffer for PTSD symptoms.


id: translation-760
author: Starnes, Victoria
title: CMV transverse myelitis in Unmanaged HIV Infection
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 324
sentence: 16
flesch: 35
cache: cache/translation-760.pdf
txt: txt/translation-760.txt
summary:
  Prior to the availability of antiretroviral therapy (ART), ATM was seen in patients with primary HIV infection due to opportunistic infections (2). We present a case of ATM attributed to cytomegalovirus secondary to uncontrolled HIV.


id: translation-333
author: Shermis, Robin B; Redfern, Roberta E; Bazydlo, John; Naimy, Gabriel; Kudrolli, Haris; Chen, John
title: Performance of Molecular Breast Imaging as an Adjunct Diagnostic Tool
date: 2019-12-02
pages: 6
extension: .pdf
mime: application/pdf
words: 4144
sentence: 264
flesch: 54
cache: cache/translation-333.pdf
txt: txt/translation-333.txt
summary:
  Duijm LE, Guit GL, Zaat JO, Koomen AR, & Willebrand D (1997) Sensitivity, speci- ficity and predictive values of breast imaging in the detection of cancer. The pos- itive reference standard was defined as histopathologic diagnosis of breast cancer, whereas negative reference standard was defined as negative biopsy results following index MBI exam or negative follow-up mammographic examination occurring at least 330 days following index MBI exam.


id: translation-202
author: Durinka, Joel B.; Wenzel, Tyler; Ortiz, Christopher; Choi, Lynn; Ortiz, Jorge
title: Fate of Abstracts Presented at the 2007-2009 Americas Hepato-Pancreato-Biliary Association Meetings
date: 2018-06-27
pages: 4
extension: .pdf
mime: application/pdf
words: 4158
sentence: 285
flesch: 55
cache: cache/translation-202.pdf
txt: txt/translation-202.txt
summary:
  Full text publication rates of studies presented at an international emergency medicine scientific meeting. Publication rates of meeting abstracts have been reviewed in orthopedics, urology, anesthesia, surgery, pediatrics, on- cology, emergency medicine, transplantation, radiology, and ophthal- mology.


id: translation-100
author: Gokula, Murthy; Gaspar, Phyllis M
date: 2014-08-21
pages: 5
extension: .pdf
mime: application/pdf
words: 3964
sentence: 199
flesch: 50
cache: cache/translation-100.pdf
txt: txt/translation-100.txt
title:
  Implementation of the FIRM (Foley Insertion, Removal, and Maintenance) protocol in skilled nursing facilities

summary:
  Attaining almost 100% documentation of rationale for catheter use resulted from implemen- tation of the protocol and efforts of the inter-professional team. Von Preyss- Friedman (12) implemented a QI project in a SNF focused on IUC and included guidelines for IUC use, follow up audit process, and an in-service of nursing staff.


id: translation-343
author: Redfern, Roberta; Brown, Megan; Izsak, Eugene
date: 2020-05-05
pages: 6
extension: .pdf
mime: application/pdf
words: 4367
sentence: 226
flesch: 50
cache: cache/translation-343.pdf
txt: txt/translation-343.txt
title:
  Medical Clearance Prior to Psychiatric Evaluation in a Tertiary Pediatric Emergency Department: Value and Cost Analysis

summary:
  Early studies of the utility of medical clearance for adult psychiatric pa- tients in the ED suggested that 63% of psychiatric patients had some underlying organic disease, discovered by this type of testing (3,4). Several other studies have also concluded that routine laboratory screening of psychiatric patients in the ED is of little value, and that most abnormalities can be anticipated in the patient’s history and physical (2,7-10).


id: translation-102
author: Brown, Megan M; Redfern, Roberta E; McPhee, Michael D
date: 2018-06-27
pages: 5
extension: .pdf
mime: application/pdf
words: 4391
sentence: 226
flesch: 46
cache: cache/translation-102.pdf
txt: txt/translation-102.txt
title:
  Relationship between compliance to quality indicators, volume, and outcomes in pancreatic cancer resection in a community hospital setting

summary:
  To assess compliance, quality indicators applying to surgical treatment of pancreatic cancer patients were identified from those put forth by Bilimoria et al in 2009 (11). Further study of the clinical relevance of pancreatic cancer quality indicators is warranted.


id: translation-346
author: Talbot, Benjamin; Jankun, Jerzy
title: Specific inhibitors of urokinase plasminogen activator for treatment of cancers; In silico approach
date: 2020-05-06
pages: 6
extension: .pdf
mime: application/pdf
words: 4459
sentence: 316
flesch: 58
cache: cache/translation-346.pdf
txt: txt/translation-346.txt
summary:
  However, for successful targeted anticancer therapy it is essential to find specific uPA inhibitors and to protect normal function of tPA. Thus, for successful targeted anticancer therapy, it is imperative to find specific uPA inhibitors, and at the same time protect normal function of other serine proteases of analogous structures, such as tPA.


id: translation-749
author: Abuhelwa, Ziad
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 242
sentence: 13
flesch: 41
cache: cache/translation-749.pdf
txt: txt/translation-749.txt
title:
  Do Zinc Supplements Reduce Mortality in Patients with COVID-19? A Systematic Review and Meta-Analysis

summary:
  Results: A total of 6 studies (3 randomized clinical trials and 3 retrospective observational studies) that included 1,670 patients with COVID-19 (855 received zinc supplements vs. 812 received standard of care without zinc) were included in our systematic review. Method: PubMed/MEDLINE, EMBASE, and Cochrane databases were searched for studies that evaluated the clinical efficacy of zinc supplements in patients diagnosed with COVID-19.


id: translation-666
author: Farrow, David
title: ERCP in Patient with Situs Inversus Totalis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 317
sentence: 14
flesch: 36
cache: cache/translation-666.pdf
txt: txt/translation-666.txt
summary:
  Case Description/Methods: An 89-year-old male presented with a history of epigastric abdominal pain for one month associated with nausea and non-bloody, non-bilious vomiting. This case details a patient found to have situs inversus totalis (SIT) while being evaluated for abdominal pain and ultimately requiring ERCP for choledocholithiasis.


id: translation-649
author: Chinnam, Sahithi
title: Hypercalcemia in the Inpatient Setting: : A Case Report
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 314
sentence: 19
flesch: 54
cache: cache/translation-649.pdf
txt: txt/translation-649.txt
summary:
  A 57-year-old female with a history of bipolar disease, depression, diabetes, and hypothyroidism presents with worsening mental status changes, visual hallucinations, and depressive symptoms. Deterioration can occur in both physical and mental functions of hypercalcemic patients acutely.


id: translation-651
author: Richard, Brennon
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 458
sentence: 19
flesch: 37
cache: cache/translation-651.pdf
txt: txt/translation-651.txt
title:
  Double Negative T Cell Proportion of CD3+ Cells Present in the Thyroid Microenvironment is an Immunogenomic Marker for Predicting Thyroid Cancer

summary:
  Furthermore, our group is working on amplifying DN T cell markers on a PCR-based platform to allow a more economically viable diagnostic test. Using High-throughput gene expression analysis, we will analyze the mRNA expression of DN T cells present in the microenvironment.


id: translation-745
author: Gangwani, Manesh
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 429
sentence: 18
flesch: 39
cache: cache/translation-745.pdf
txt: txt/translation-745.txt
title:
  Efficacy and Safety of EUS-directed Transgastric ERCP (EDGE) vs Laparoscopic-Assisted ERCP: : A Systematic Review and Meta-Analysis

summary:
  A Systematic Review and Meta-Analysis Manesh Kumar Gangwani, MD1*, Hossein Haghbin, MD1, Fnu Priyanka, MD1, Yousaf Hadi, MD1, Dushyant Singh Dahiya, MD1, Faisal Kamal, MD1, Wade Lee-Smith, MLS2, Ali Nawras, MD3, Muhammad Aziz, MD3, Douglas G Adler, MD4 1Division of Hospital Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Gastroenterology and Hepatology, Department of Medicine, The University of Toledo, Toledo, OH 43614 3Department of University Libraries, The University of Toledo, Toledo, OH 43614 4Director of Therapeutic Endoscopy and Director of Gastroenterology Fellowship Training Program University of Utah, School of Medicine, Salt Lake City, UT 84132 *Corresponding author: manesh.gangwani@utoledo.edu Published: 05 May 2023 Background: The altered anatomy in Roux-en-Y gastric bypass (RYGB) makes conventional Endoscopic retrograde cholangiopancreatography (ERCP) a technically challenging procedure. May 5; 11(1):e1-e2 Efficacy and Safety of EUS-directed Transgastric ERCP (EDGE) vs Laparoscopic-Assisted ERCP:


id: translation-664
author: Farrow, David
title: Rectal Ischemia Status Post EVAR and COVID-19
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 331
sentence: 18
flesch: 38
cache: cache/translation-664.pdf
txt: txt/translation-664.txt
summary:
  It is hypothesized that a hypercoagulable state caused by COVID-19 infection coupled with ongoing hypotension in the setting of critical illness in our patient with significant peripheral arterial disease led to the low flow state in bilateral iliac arteries causing ischemic proctitis. During his admission, he was found to have acute left lower extremity ischemia requiring stenting of his superficial femoral artery and abdominal endovascular aneurysm repair (EVAR).


id: translation-758
author: Nguyen, Dylan
title: Protease-Inhibitor Binding Reveals Conformational Transition Mechanism
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 327
sentence: 14
flesch: 33
cache: cache/translation-758.pdf
txt: txt/translation-758.txt
summary:
  To confront HIV-1 protease drug resistance, Ghosh and colleagues developed protease inhibitors modeled after FDA approved HIV-1 protease inhibitor, Darunavir. In clinic, protease inhibitors are commonplace in the multi-drug regimens used by physicians to combat drug-resistant HIV strains with an unfortunate exchange for greater patient toxicity.


id: translation-655
author: Lad, Apurva
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 395
sentence: 13
flesch: 29
cache: cache/translation-655.pdf
txt: txt/translation-655.txt
title:
  Cyanotoxin Degrading Lake Bacteria Significantly Alleviate Microcystin-LR Induced Hepatotoxicity in Both In Vitro and In Vivo Models

summary:
  Mass spectrometric analysis of urine from mice pre-treated with the bacteria prior to MC-LR exposure, revealed significant reduction in urine MC-LR levels and elevated levels of the detoxified metabolite - MC-LR Cysteine as compared to the untreated control group. https://dx.doi.org/10.46570/utjms.vol11-2023-655 https://dx.doi.org/10.46570/utjms.vol11-2023-655 mailto:Apurva.Lad@rockets.utoledo.edu https://dx.doi.org/10.46570/utjms.vol11-2023-655 UTJMS 11(1):e1-e2 https://dx.doi.org/10.46570/utjms.vol11-2023-655 2 ©2023 UTJMS Conclusion: These results suggest a potential novel therapeutic approach that can be developed for MC- LR induced toxicity.


id: translation-243
author: Brewer, Shawn P.; Jankun, Jerzy
date: 2018-09-28
pages: 7
extension: .pdf
mime: application/pdf
words: 4976
sentence: 367
flesch: 52
cache: cache/translation-243.pdf
txt: txt/translation-243.txt
title:
  Bifunctional inhibitors of urokinase and metalloproteinase-9 for cancer treatment - in silico evaluation

summary:
  Consequently human clini- cal studies were designed inhibiting urokinase or MMPs, but these 8 utdc.utoledo.edu/Translation Brewer et al. target specific inhibitors producing mixed results (64-67). Towle MJ, et al. (1993) Inhibition of urokinase by 4-substituted benzo[b]thiophene-2-carboxamidines: an important new class of selective synthetic urokinase inhibitor.


id: translation-747
author: Gayfield, Scott
title: Myasthenic Crisis-Induced Takotsubo Cardiomyopathy: : What to Know
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 188
sentence: 8
flesch: 29
cache: cache/translation-747.pdf
txt: txt/translation-747.txt
summary:
  Myasthenic Crisis-Induced Takotsubo Cardiomyopathy: What to Know Scott Gayfield1*, Joshua Busken1, Sarmed Mansur1 1Division of Hospital Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: scott.gayfield@rockets.utoledo.edu Published: 05 May 2023 Myasthenia gravis (MG) is an autoimmune disorder in which antibodies are formed against post- synaptic nicotinic acetylcholine receptors that leads to impeded muscle contraction, and commonly affects the oculomotor muscles. MG can be complicated by myasthenic crisis (MC), a life-threatening exacerbation of myasthenic weakness that can lead to respiratory depression and possibly even death.


id: translation-756
author: Kammeyer, Joel
date: 2023-05-03
pages: 3
extension: .pdf
mime: application/pdf
words: 573
sentence: 19
flesch: 24
cache: cache/translation-756.pdf
txt: txt/translation-756.txt
title:
  A Pathway of Distinction in Global Health – : A Professional Development Model to Prepare Medical Students as Future Global Health Leaders

summary:
  The initial Pathway of Distinction in Global Health at the UTCOMLS consists of three foundational requirements for medical students. Medical students that complete all three requirements will be awarded a “Distinction in Global Health” upon graduation.


id: translation-657
author: Battepati, Dhanushya
title: Severe Transaminitis in Allopurinol-Induced DILI presenting as DRESS Syndrome
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 342
sentence: 18
flesch: 41
cache: cache/translation-657.pdf
txt: txt/translation-657.txt
summary:
  The patient we present demonstrates a hepatocellular pattern of liver injury. Liver injury pattern in drug reaction with eosinophilia and systemic symptoms (DRESS) is either cholestatic or hepatocellular.


id: translation-360
author: Gotfried, Robert
title: Ehrlichiosis in Southern Ohio: Two case reports and a review of the literature
date: 2023-07-06
pages: 8
extension: .pdf
mime: application/pdf
words: 5304
sentence: 338
flesch: 55
cache: cache/translation-360.pdf
txt: txt/translation-360.txt
summary:
  Southern Ohio in particular, has been identified as having a high preponderance of E. chaffeensis infected ticks (8). While the clinical manifestations of E. chaffeensis infection are nonspecific, laboratory abnormalities provide important diagnostic clues.


id: translation-653
author: Aziz, Muhammad
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 332
sentence: 17
flesch: 45
cache: cache/translation-653.pdf
txt: txt/translation-653.txt
title:
  Does I-Scan Improve Adenoma Detection Rate Compared to High-Definition Colonoscopy? : A Systematic Review and Meta-Analysis

summary:
  Full-text RCTs and cohort studies directly comparing i-scan and HD colonoscopy were deemed eligible for inclusion. Future studies evaluating other outcomes of interest such as proximal adenomas and serrated lesions are warranted.


id: translation-751
author: Esser, Katherine
title: Daptomycin Induced Rhabdomyolysis and Subsequent Compartment Syndrome: : A Case Report
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 319
sentence: 15
flesch: 22
cache: cache/translation-751.pdf
txt: txt/translation-751.txt
summary:
  We present a case of a 56-year-old who developed compartment syndrome after daptomycin treatment for a S. aureus infection of a penile implant. Discussion: While compartment syndrome occurs secondarily to fractures in 75% of cases, it can also be a sequelae of soft tissue injuries, poor positioning during surgery, burns, vascular injuries, infections, and medication.


id: translation-761
author: Starnes, Victoria
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 324
sentence: 21
flesch: 31
cache: cache/translation-761.pdf
txt: txt/translation-761.txt
title:
  Streptococcal Pneumoniae Mycotic Aneurysm: : A Rare Case of Disseminated Pneumococcal Disease in an Immunocompetent Host

summary:
  Our case highlights the importance of vaccinations in preventing disseminated infection in even the healthiest of patients. Mycotic abdominal aortic aneurysm (MAAA) is a rare infection of the aortic wall that may progress to aortic rupture.


id: translation-301
author: Jankun, Jerzy
title: Richard Hart (1947-2018)
date: 2019-06-04
pages: 3
extension: .pdf
mime: application/pdf
words: 876
sentence: 38
flesch: 51
cache: cache/translation-301.pdf
txt: txt/translation-301.txt
summary:
  For many years Richard was a long-time volunteer at McGill University and was a founding member of the Faculty of Science Advisory Board (now the Science Campaign Committee). Richard came from New Zealand through Europe to Canada to undertake doctoral studies in chemistry at McGill University, Montreal.


id: translation-240
author: Roberts, Kasey; Buchenroth, Britta; Novi, Joseph
title: Chronic Uterine Dehiscence Secondary to Genitourinary Tuberculosis: A Case Report
date: 2018-09-28
pages: 3
extension: .pdf
mime: application/pdf
words: 1625
sentence: 92
flesch: 53
cache: cache/translation-240.pdf
txt: txt/translation-240.txt
summary:
  In reporting this unexpected case of likely GU TB, we hope to have highlighted the importance of keeping the disease on the differential for cases that present similarly. One study examining the presenting complaints of 44 Sudanese women with pelvic TB found that 80% of affected women complained of chronic pelvic and lower abdominal pain, 48% of dyspareunia, 40% of infertility, 28% of menstrual dysfunction, and 20% of dys- menorrhea (1).


id: translation-285
author: Yousif, Gheith
title: Critical Hypomagnesemia and Seizure Induced by Chronic Use of Proton Pump Inhibitors (PPIs)
date: 2019-06-12
pages: 3
extension: .pdf
mime: application/pdf
words: 2017
sentence: 107
flesch: 48
cache: cache/translation-285.pdf
txt: txt/translation-285.txt
summary:
  Critically low magnesium level may lead to fatal seizure activity, which could lead to death if went undi- agnosed. Despite resolution of her vomiting and diarrhea, she continued to have low magnesium levels.


id: translation-765
author: Chen, Bohan
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 352
sentence: 16
flesch: 20
cache: cache/translation-765.pdf
txt: txt/translation-765.txt
title:
  Pharmacological Melanocortin 5 Receptor Activation Attenuates Glomerular Injury and Proteinuria in Rats with Puromycin Aminonucleoside Nephrosis

summary:
  Treatment with MC5R-A attenuated urine protein excretion and mitigated the loss of podocyte marker proteins, resulting in improved podocyte ultrastructural changes. Results: Upon PAN injury, rats developed evident proteinuria on day 5, denoting an established nephrotic glomerulopathy.


id: translation-767
author: Faleel, Dhilhani
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 373
sentence: 14
flesch: 33
cache: cache/translation-767.pdf
txt: txt/translation-767.txt
title:
  Computational and Experimental Analysis Reveals the Arachidonic Acid Metabolite 20-Hydroxyeicosatetraenoic Acid is a Novel Ligand of the Na/K-ATPase

summary:
  This docking analysis predicted that 20-HETE and 5,14-20-HEDE interact with the NKA with similar binding free energy as cardiotonic steroids (Predicted binding free energies: telocinobufagin =-9.2; 20-HETE= -8.5 and 5,14-20-HEDE = -8.18). We further sought to test the ability of 20-HETE to stimulate NKA mediated signaling in renal proximal tubule cells.


id: translation-763
author: Chen, Bohan
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 381
sentence: 13
flesch: 25
cache: cache/translation-763.pdf
txt: txt/translation-763.txt
title:
  MC1R Deficiency Enhances Th1 Response and Impairs Regulatory T Cell Homeostasis In Nephrotoxic Serum Nephritis

summary:
  Moreover, shown by immunohistochemistry staining, the number of FoxP3+ regulatory T cells in the NTS nephritic kidneys was diminished in e/e mice, as compared with WT mice. The exacerbated NTS nephritis in e/e mice was associated with greater levels of autologous IgG2c and IgG3 either deposited in glomeruli or in sera.


id: translation-775
author: Carsel, Alex
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 327
sentence: 15
flesch: 28
cache: cache/translation-775.pdf
txt: txt/translation-775.txt
title:
  Reversal of Spironolactone-Induced Gynecomastia: : A Review and Case Report of Spironolactone-Induced Gynecomastia

summary:
  All included studies demonstrated resolution of gynecomastia with discontinuation of spironolactone or replacement with eplerenone. Conclusion: Based on the results of this review, it is clear that there is a significant gap in the literature pertaining to the importance of identifying and treating gynecomastia, and reversing spironolactone- induced gynecomastia in patients with heart failure and cirrhosis. Eplerenone, a more selective aldosterone inhibitor compared to spironolactone, is cited as an alternative that can reverse spironolactone-induced gynecomastia in patients with hyperaldosteronism and cirrhosis.


id: translation-318
author: Levine, Jason Andrew; Hovsepyan, Karen; Lubarsky, Daniel; Mukundan, Deepa; Ruddy, Jennifer
title: Streptococcus Intermedius Lung Abscess in a 17-year-old Male
date: 2019-12-03
pages: 5
extension: .pdf
mime: application/pdf
words: 2225
sentence: 145
flesch: 47
cache: cache/translation-318.pdf
txt: txt/translation-318.txt
summary:
  The most common type of Streptococcus intermedius infection in the pediatric population is a sinusitis (12), and it was presented that hematogenous dissemination is the main mechanism in children. This proposition was supported by the fact that in one third of cases with Streptococcus intermedius abscesses, blood culture was found to be positive (7, 12).


id: translation-204
author: McGinnis, Ronald
title: New Opportunities For Research Publication
date: 2018-06-27
pages: 1
extension: .pdf
mime: application/pdf
words: 369
sentence: 14
flesch: 31
cache: cache/translation-204.pdf
txt: txt/translation-204.txt
summary:
  Medical  schools  around  the  world  are   adopting  this  concept  to  facilitate  publication   resulting  from  early  research  involvement  of  students   and  the  transition  to  academic  medicine  of  residents   and  fellows.                   I  would  like  to  congratulate  the  Editorial  Staff  for   launch  of  UT’s  new  online  journal,  Translation:  The  University  of  Toledo  Journal  of  Medical   Sciences.   


id: translation-84
date: 2014-07-10
pages: 4
extension: .pdf
mime: application/pdf
words: 2931
sentence: 189
flesch: 59
cache: cache/translation-84.pdf
txt: txt/translation-84.txt
author:
  Brickman, Kristopher A.; Blair, Alex B.; Tamburrino, Marijo B.; Dzurik, Alexander D.; Xie, Hong; Smirnoff, Jennifer B.; Wang, Xin

title:
  The Quantitative Minor Injury Scale: Pilot Study of a Scale to Measure Level of Minor Injury after Motor Vehicle Collisions

summary:
  A significant cor- relation (R=0.366; p=0.039; n=32) was found with the QMIS score and depression symptoms as measured by the CES-D. Conclusions: Results suggest the QMIS creates differentiation among a population of minor injury patients and may be useful in examining the relationship between minor injury and psychologi- cal conditions. Discussion The lack of quantitative evaluation of minor injury severity im- pedes research on post-MVC psychiatric symptoms.


id: translation-777
author: Kelly, Gavin
title: Hyperpigmentation in Systemic Sclerosis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 310
sentence: 17
flesch: 35
cache: cache/translation-777.pdf
txt: txt/translation-777.txt
summary:
  Results: Hyperpigmentation, particularly diffuse hyperpigmentation, has previously been linked to increase incidence of digital ulcers in SSc patients. It is hypothesized that increased endothelin-1 in SSc patients play a role in increased melanin synthesis in these patients.


id: translation-679
author: Waack, Andrew
title: Epididymo-orchitis Secondary to Colovesical Fistula
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 313
sentence: 20
flesch: 45
cache: cache/translation-679.pdf
txt: txt/translation-679.txt
summary:
  May 5; 11(1):e1-e1 Epididymo-orchitis Secondary to Colovesical Fistula Andrew Waack1*, Meghana Ranabothu, M21, Neha J Patel, MD1 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: Andrew.waack@rockets.utoledo.edu Published: 05 May 2023 Introduction: Acute epididymo-orchitis is a common cause of scrotal pain in adults. We present a unique case of epididymo-orchitis secondary to colovesical fistula caused by chronic diverticulitis.


id: translation-779
author: Meisler, Adam
title: Iatrogenic Horner's Syndrome Due to Chest Tube Compression during Decortication
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 377
sentence: 17
flesch: 42
cache: cache/translation-779.pdf
txt: txt/translation-779.txt
summary:
  We present an iatrogenic cause of Horner’s syndrome due to compressive injury to the sympathetic chain by chest tube placement during decortication surgery. Discussion: Peripheral Horner’s syndrome is rare complication that can occur with intrathoracic surgeries and chest tube placement.


id: translation-781
author: Noori, Zaid
title: Rare Case of Mantle Cell Lymphoma Presented as Malignant Pleural Effusion and Pleural Nodules
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 473
sentence: 25
flesch: 48
cache: cache/translation-781.pdf
txt: txt/translation-781.txt
summary:
  Pleural fluid that was obtained by thoracentesis was noted to be bloody and exudative (LDH: 750 Units/L, Protein 4.7 g/dL, Glucose 12 mg/dL, Lymphocytes 70%). Pleural involvement reported only in about one percent of cases.


id: translation-677
author: Akpunonu, Basil
title: Anaplastic Large Cell Lymphoma Presenting as Ulcerative Facial Mass: : A Case Report
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 345
sentence: 16
flesch: 32
cache: cache/translation-677.pdf
txt: txt/translation-677.txt
summary:
  Anaplastic large cell lymphoma (ALCL) is a rare form of non-Hodgkin lymphoma (NHL) that can be aggressive with rapid speed, thus mandating a timely diagnosis to optimize treatment and deter progression. The cutaneous involvement may resemble common dermatologic conditions, delaying diagnosis.


id: translation-681
author: Sayeh, Wasef
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 389
sentence: 17
flesch: 44
cache: cache/translation-681.pdf
txt: txt/translation-681.txt
title:
  Early Feeding Versus Delayed Feeding after Therapeutic Endoscopic Intervention in Upper GI Bleeding: : A Systematic Review and Meta-analysis

summary:
  The secondary outcomes were the occurrence of early bleeding, late bleeding and the length of hospital stay. Our meta-analysis demonstrated that early feeding after endoscopic interventions in patients with upper GI bleeding appears to be relatively safe.


id: translation-685
author: Renno, Anas
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 384
sentence: 19
flesch: 41
cache: cache/translation-685.pdf
txt: txt/translation-685.txt
title:
  Efficacy and Safety of Cap Assisted vs. Conventional Endoscopic Esophageal Foreign Body Removal - : Systematic Review and Meta-analysis

summary:
  May 5; 11(1):e1-e2 Efficacy and Safety of Cap Assisted vs. Conventional Endoscopic Esophageal Foreign Body Removal- Systematic Review and Meta-analysis Anas Renno1*, Zohaib Ahmed MD1, Syeda Faiza Arif MD1, Stephanie Lin Ong MD1, Joyce Badal MD1, Wade lee-Smith MLS2, Umer Farooq MD1, Muhammad Aziz MD1, Yaseen Alastal MD1, Ali Nawras MD1 1Division of Gastroenterology and Hepatology, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Department of University Libraries, The University of Toledo, Toledo, OH 43614 https://dx.doi.org/10.46570/utjms.vol11-2023-685 https://dx.doi.org/10.46570/utjms.vol11-2023-685 mailto:anas.renno@utoledo.edu https://dx.doi.org/10.46570/utjms.vol11-2023-685 UTJMS 11(1):e1-e2 https://dx.doi.org/10.46570/utjms.vol11-2023-685 2 ©2023 UTJMS Conclusion: This systematic review and meta-analysis showed that the cap-assisted technique has higher efficacy and better safety than conventional techniques.


id: translation-683
author: Renno, Anas
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 463
sentence: 22
flesch: 39
cache: cache/translation-683.pdf
txt: txt/translation-683.txt
title:
  Recurrent Pancreatitis Secondary to Common Channel Volvulus through Petersen’s Space Defect in a Patient with Roux-En-Y Bypass

summary:
  We present a case of recurrent pancreatitis in a patient with Roux-En-Y bypass found to have common channel hernia through a Petersen’s space defect. This case demonstrates recurrent pancreatitis in a patient with a history of Roux-En-Y bypass found to have a common channel volvulus through a Petersen’s space defect.


id: translation-752
author: Kammeyer, Joel
title: An Alprostadil Intracavernosal Injection Leading to a Psoas Muscle Abscess
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 347
sentence: 19
flesch: 41
cache: cache/translation-752.pdf
txt: txt/translation-752.txt
summary:
  Alprostadil is a synthetic prostaglandin E1 that can be self-administered via intracavernosal injection as a vasodilatory treatment for erectile dysfunction. The case offers an example of intracavernosal injection of alprostadil precipitating psoas muscle abscess, as opposed to more common cavernous or penile abscesses.


id: translation-754
author: Kammeyer, Joel
title: Fatal central pontine myelinolysis in a patient with uncontrolled HIV and normal sodium levels
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 331
sentence: 20
flesch: 38
cache: cache/translation-754.pdf
txt: txt/translation-754.txt
summary:
  Treatment of CPM with normal electrolytes includes addressing underlying causes that could precipitate metabolic derangement or increased permeability of the blood-brain barrier; this means management of underlying HIV even in a previously asymptomatic patient. While HIV affects the nervous system in up to 90% of patients, CPM remains rare.


id: translation-339
author: Kheireldin, Rowida
title: A Case Report of Clobazam Toxicity Related to Cannabidiol and Clobazam Drug-drug Interaction
date: 2019-12-03
pages: 3
extension: .pdf
mime: application/pdf
words: 1894
sentence: 120
flesch: 55
cache: cache/translation-339.pdf
txt: txt/translation-339.txt
summary:
  We recom- mend obtaining baseline Clobazam level before starting CBD and monitoring Clobazam levels every two weeks for a few months to avoid side effects and toxicity. We also rec- ommend monitoring Clobazam levels every two weeks for the first few months to avoid side effects and toxicity.


id: translation-269
author: Koffman, Boyd
title: Migraine Headache associated with Multiple Sclerosis: Results from the Nationwide Inpatient Sample
date: 2021-04-25
pages: 5
extension: .pdf
mime: application/pdf
words: 3342
sentence: 226
flesch: 60
cache: cache/translation-269.pdf
txt: txt/translation-269.txt
summary:
  Objecctives: In this study, we investigated headache prevalence and association in MS patients. The prevalence of migraine among MS patients (7%) was significantly higher than the control group (2.8%).


id: translation-762
author: Waack, Andrew
title: Herpes Simplex Virus-1 Encephalitis Secondary to Whole Brain Radiation Therapy
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 323
sentence: 19
flesch: 31
cache: cache/translation-762.pdf
txt: txt/translation-762.txt
summary:
  Importantly, reported HSE cases following WBRT demonstrate an atypical presentation of encephalitis. Empirical intravenous acyclovir was initiated upon suspicion of possible HSE.


id: translation-672
author: Halloran, Sean
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 331
sentence: 19
flesch: 40
cache: cache/translation-672.pdf
txt: txt/translation-672.txt
title:
  Discovery of Gastric Adenocarcinoma during PEG Tube Placement in Patient with Epiglottic Squamous Cell Carcinoma

summary:
  Case Description: A 77-year old male presented for upper endoscopy with PEG tube placement. He was referred for PEG tube placement for nutrition supplementation due to 5 months of progressive dysphagia, malnutrition, and unintentional weight loss.


id: translation-344
author: Beeson, Rachel; Stefanopoulos, Stavros; Daniel Rapport; Jorge Ortiz
title: Kidney Transplant Recipient with Conversion Disorder Treated with Electroconvulsive Therapy
date: 2020-05-19
pages: 3
extension: .pdf
mime: application/pdf
words: 2653
sentence: 181
flesch: 53
cache: cache/translation-344.pdf
txt: txt/translation-344.txt
summary:
  ECT may be considered in patients with severe conversion disorder with a previous history of successful treatment. Conclusion ECT in the treatment of severe conversion disorder may be ap- propriate and result in good clinical outcome.


id: translation-674
author: Jay, Bryanna
title: Primary Gastric Squamous Cell Carcinoma with Concurrent H. Pylori Infection and Colonic Metastasis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 326
sentence: 19
flesch: 45
cache: cache/translation-674.pdf
txt: txt/translation-674.txt
summary:
  H. pylori infection is a known risk factor for gastric malignancies but, only one case has been reported with an association between the two. Primary gastric squamous cell carcinoma (PGSCC) is a rare, aggressive, malignancy that requires EGD with biopsy and pathology for diagnosis.


id: translation-774
author: Busken, Joshua
title: Pembrolizumab-induced Pneumonitis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 218
sentence: 13
flesch: 35
cache: cache/translation-774.pdf
txt: txt/translation-774.txt
summary:
  Conclusion: Pembrolizumab induced pneumonitis is a rare but life-threatening complication. *Corresponding author: Joshua.busken@rockets.utoledo.edu Published: 05 May 2023 Introduction: Pembrolizumab is a monoclonal antibody targeting the anti-programmed death protein 1, which is present on the surface of T and B cells.


id: translation-242
author: Yousif, Gheith; Phelps, Kevin; Gotfried, Robert
date: 2018-09-28
pages: 5
extension: .pdf
mime: application/pdf
words: 3471
sentence: 172
flesch: 54
cache: cache/translation-242.pdf
txt: txt/translation-242.txt
title:
  The Importance of Following ACC/AHA Cholesterol Guidelines 2013 by Residents’ Physicians to Reduce Atherosclerotic Cardiovascular Disease in Different Populations Gheith Yousif, MD/MBChB, Kevin Phelps, DO., Robert Gotfried, DO. University of Toledo/Family Medicine Department

summary:
  This means that our residents are diligent when prescribing statins for high risk patients, but still there is room for improvement. The charts reviewed were selected from among patients cared for by Family Medicine residents at the University of Toledo Family Medicine Center, Glendale Medical East Clinic (GME).


id: translation-74
author: Koch, Terah; Al-Hashimi, Ibtisam; Koffman, Boyd M.; Deshpande, Abhishek; Khuder, Sadik A.
title: Comorbidities associated with Sjögren's syndrome: Results from the Nationwide Inpatient Sample.
date: 2014-04-02
pages: 4
extension: .pdf
mime: application/pdf
words: 3738
sentence: 213
flesch: 54
cache: cache/translation-74.pdf
txt: txt/translation-74.txt
summary:
  Similar results were observed in a more recent cohort study, which estimated that the relative risk of de- veloping lymphoma was about 16-fold higher in SS patients than gen- eral population and that this risk increased over time and remained high, even 15 years after SS diagnosis (19). Secondary SS is closely associated with rheumatoid arthritis and is believed to have a different patho- genesis than primary SS (1).


id: translation-101
date: 2018-06-27
pages: 3
extension: .pdf
mime: application/pdf
words: 3070
sentence: 144
flesch: 56
cache: cache/translation-101.pdf
txt: txt/translation-101.txt
author:
  Brickman, Kristopher A; Zaciewski, Tomas G; Bahl, Rajiv; Fink, Brian N; Gibbons, Maureen P; Sidani, Ramzi S; Audino, Anthony N; Ryno, Joseph J; Adams, Daniel Z; Wellock, Austin R

title:
  Iontophoresis: as a new treatment modality in the management of acute soft tissue injuries in the emergency department

summary:
  Iontophoresis: as a new treatment modality in the management of acute soft tissue injuries in the emergency department Kristopher A. Brickman a, Tomas G. Zaciewski a , Rajiv Bahl a 1, Brian N. Fink a , Maureen P. Gibbons a , Ramzi S. Sidani a , Anthony N. Audino a , Joseph J. Ryno a , Daniel Z. Adams a , and Austin R. Wellock a aUniversity of Toledo Health Science Campus, Toledo, OH 43614 Background: Iontophoresis utilizes a transcutaneous process to deliver charged medication to a localized area of injury via an elec- trical current to remedy pain symptoms. The current ED standard of care for treating acute soft tissue injuries is immobi- lization and use of non-steroidal anti-inflammatory drugs (NSAIDs).


id: translation-687
author: Doddi, Sishir
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 378
sentence: 15
flesch: 27
cache: cache/translation-687.pdf
txt: txt/translation-687.txt
title:
  Prevalence and Clinical Significance of Antiphospholipid Antibodies in Hospitalized Patients with COVID-19 Infection

summary:
  Previous literature suggests that the presence of antiphospholipid antibodies (APA) is an important factor for thrombosis in COVID-19 patients. This single-institution retrospective study aims to find if the prevalence of APA in COVID-19 patients has any clinical significance.


id: translation-776
author: Crawford, Erin L>
title: Use of Internal Standards to Develop Improved Methylation Detection in cfDNA
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 333
sentence: 14
flesch: 36
cache: cache/translation-776.pdf
txt: txt/translation-776.txt
summary:
  *Corresponding author: Erin.crawford@rockets.utoledo.edu Published: 05 May 2023 Detection of aberrant levels and patterns of methylation in circulating free genomic DNA (cfDNA) may be useful in predicting the presence of malignancy in a particular tissue or in monitoring known malignancies for recurrence or treatment resistance. Initial testing of an off-the-shelf IS yielded promising results but, technical error increased as methylation increased, likely due to suboptimal IS design and experimental conditions.


id: translation-764
author: Chen, Bohan
title: Negative Modulation of B Cell Activation by MC1R Signaling Protects Against Membranous Nephropathy
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 321
sentence: 14
flesch: 27
cache: cache/translation-764.pdf
txt: txt/translation-764.txt
summary:
  Results: MC1R KO exacerbated proteinuria, podocyte injury and glomerulopathy, associated with enhanced glomerular deposition of autologous IgG and the C5b-9 complement complex, denoting a sensitized autologous humoral immune response. Mechanistically, MC1R was evidently expressed in B lymphocytes, and negatively associated with B cell activation as revealed by gene set enrichment analysis.


id: translation-766
author: Dube, Prabhatchandra
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 405
sentence: 14
flesch: 24
cache: cache/translation-766.pdf
txt: txt/translation-766.txt
title:
  Oxalate Diet Induced Chronic Kidney Disease in Dahl-Salt-Sensitive Rats Induces Uremic Cardiomyopathy

summary:
  We hypothesized that SS rats fed a high oxalate diet will develop cardiac dysfunction compared to SS rats fed a normal chow diet. Dahl-salt-sensitive rats (SS) are mainstay models of hypertensive renal disease; however, characterization of other diet-induced CKD models with uremic cardiomyopathy would allow for comparative studies.


id: translation-199
author: Durinka, Joel B.; Ortiz, Jorge
title: Fate of Poster Abstracts Presented at the 2009 American College of Surgeons Clinical Congress
date: 2017-06-27
pages: 4
extension: .pdf
mime: application/pdf
words: 4320
sentence: 265
flesch: 55
cache: cache/translation-199.pdf
txt: txt/translation-199.txt
summary:
  After a review of the literature covering meetings from 2000- 2009, publication rates of meeting abstracts have been reviewed for different medical specialties, such as orthopedics, urology, anesthe- sia, surgery, pediatrics, oncology, emergency medicine, radiology, and ophthalmology. The full-length manuscript publication rate of meeting abstracts not only illustrates the quality of research conducted by an institu- tion’s investigators but also portrays the activity and reputation of a particular scientific meeting and its society members.


id: translation-768
author: George, Jerrin
title: A Case Series of Potential Cyanotoxin Exposure
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 259
sentence: 14
flesch: 24
cache: cache/translation-768.pdf
txt: txt/translation-768.txt
summary:
  Potential cyanotoxin exposure occurred while swimming in the Maumee River and Maumee State Park in Northwest OH during the summer months which coincide with peak HAB activity. Conclusion: Symptoms following potential cyanotoxin exposure coincide with multiple disease states representing an urgent need to develop specific diagnostic tests of exposure.


id: translation-770
author: Al-Ataby, Harith A.
title: Pleural plasmacytomas in a Patient with Multiple Myeloma Relapse
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 322
sentence: 16
flesch: 46
cache: cache/translation-770.pdf
txt: txt/translation-770.txt
summary:
  *Corresponding author: harith.al-ataby@utoledo.edu Published: 05 May 2023 Introduction: Pleural plasmacytoma in the setting of relapsed multiple myeloma (MM) is a rare yet serious condition, less than 10 cases have been reported in the literature. Discussion: Pleural plasmacytomas are extremely rare and account for around 3-6% of extramedullary disease in MM patients.


id: translation-103
author: Menezes, Krishe; Deogaonkar, Milind; Bajpai, Vatsal
date: 2018-06-27
pages: 4
extension: .pdf
mime: application/pdf
words: 3578
sentence: 220
flesch: 58
cache: cache/translation-103.pdf
txt: txt/translation-103.txt
title:
  Vim stimulation as a predictor of response to deep brain stimulation in patients of severe tremor undergoing dual stimulation

summary:
  Additions consist of stimulation of an additional nucleus e.g. If a patient has had Vim stimulation then an addition would consist of Vim + Raprl stimulation (See Fig. 1 below). We also conclude that for severe es- sential tremor, Raprl stimulation showed a better response than Vim stimulation.


id: translation-778
author: Knight, Connor
title: Working To Understand Familial Lung Cancer And Its Genetic Underpinnings
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 320
sentence: 19
flesch: 49
cache: cache/translation-778.pdf
txt: txt/translation-778.txt
summary:
  In this study we processed blood and buccal swab samples collected from affected and unaffected members of families with statistically significant enrichment for lung cancer. Mean DNA yield for blood samples was 301 µg and for buccal swabs was 8.86 µg.


id: translation-676
author: O’Shea, Daniel
title: Gastrointestinal Ulceration as a Manifestation of Severe Dermatomyositis -: A Case Report
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 317
sentence: 19
flesch: 38
cache: cache/translation-676.pdf
txt: txt/translation-676.txt
summary:
  May 05; 11(1):e1-e1 Gastrointestinal Ulceration as a Manifestation of Severe Dermatomyositis - A Case Report Daniel O’Shea1*, Dhanushya Battepati1, Brandon Speedy1, David Farrow MD1, Megan Karrick DO1, Anas Renno MD1, Benjamin Hart MD1 1Division of Gastroenterology and Hepatology, Department of Medicine, The University of Toledo, Toledo, OH 43614 Three months later, a diagnosis of acute fulminant dermatomyositis was made with NXP-2, GAD-65 positivity on biopsy.


id: translation-682
author: Ranabothu, Meghana
title: Rare Occurrence of Primary Gastric Lymphoma: : A Case Report
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 268
sentence: 16
flesch: 40
cache: cache/translation-682.pdf
txt: txt/translation-682.txt
summary:
  Conclusion: Primary gastric lymphoma is a rare cause of gastric mass. Primary gastric lymphoma (PGL), a rare gastrointestinal cancer, arises from lymphocytes found in the lamina propria of the stomach because of chronic inflammation.


id: translation-680
author: Sayeh, Wasef
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 387
sentence: 16
flesch: 43
cache: cache/translation-680.pdf
txt: txt/translation-680.txt
title:
  EUS Guided Gastroenterostomy Vs Surgical Gastrojejunostomy for the Palliation of Malignant Gastric Outlet Obstruction: : A Systemic Review and Meta-analysis

summary:
  However, very few studies were done on less aggressive procedures including EUS guided gastroenterostomy (EUS-GE). A Systemic Review and Meta- analysis Wasef Sayeh1*, Azizullah Beran, MD1, Sami Ghazaleh, MD1, Amna Iqbal, MD1, Justin Chuang, Mohammad Safi, MD1, Saif-Eddin Malhas, MD1, Ziad Abuhelwa, MD1, Waleed Kokher, MD1, Omar Sajdeya, MD1, Muhammad Aziz, MD2, Ajit Ramadugu, MD2, Ali Nawras, MD2 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Gastroenterology and Hepatology, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: wasef.sayeh@utoledo.edu Published: 05 May 2023 Background: Gastric Outlet Obstruction (GOO) was traditionally treated palliatively with surgical gastrojejunostomy (SGJ).


id: translation-678
author: Sayeh, Wasef
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 393
sentence: 19
flesch: 47
cache: cache/translation-678.pdf
txt: txt/translation-678.txt
title:
  EUS Guided Through the Needle Biopsy Versus Fine Needle Aspiration for Pancreatic Cystic Lesions: : A Systemic Review and Meta-analysis

summary:
  Recent studies have investigated the EUS guided through the needle biopsy (EUS-TTNB) as an alternative method. EUS-TTNB should be considered https://dx.doi.org/10.46570/utjms.vol11-2023-678 https://dx.doi.org/10.46570/utjms.vol11-2023-678 mailto:wasef.sayeh@utoledo.edu https://dx.doi.org/10.46570/utjms.vol11-2023-678 UTJMS 11(1):e1-e2 https://dx.doi.org/10.46570/utjms.vol11-2023-678 2 ©2023 UTJMS where applicable clinically for improving the diagnostic yield in patients undergoing evaluation of PCLs.


id: translation-201
date: 2022-12-20
pages: 7
extension: .pdf
mime: application/pdf
words: 4249
sentence: 230
flesch: 54
cache: cache/translation-201.pdf
txt: txt/translation-201.txt
author:
  Karipineni, Farah; Parsikia, Afshin; Chang, PoNan; Pang, John; Campos, Stalin; Khanmoradi, Kamran; Zaki, Radi; Ortiz, Jorge

title:
  Dispelling the myth of Asian homogeneity: Improved outcomes of Chinese Americans after kidney transplantation

summary:
  Perioperative wound infection prophylaxis UTJMS 10:e1-e7 Karipineni et al 10.46570/utjms.vol10-2016-201 4 ©2022 UTJMS Chinese Other Asians Whites (n=37) (n=54) (n=346) (n=437) p-value 13.9 (6) 15.1 (6.9) 14 (7.4) 14.1 (7.2) 0.640 37.5 (36.2) 31.8 (19.3) 37.3 (19.6) 36.6 (21.5) 0.235 1.5 (1) 1.9 (1.9) 1.7 (0.9) 1.7 (1.2) 0.299 10.9 (26.3) 11.9 (29.7) 14.7 (30.2) 14 (29.7) 0.655 1 (0.4) 1.1 (0.5) 1.1 (1.1) 1.1 (1) 0.935 4 (10.8) 3 (5.6) 15 (4.3) 22 (5) 0.227 0.095 0 1 Chinese subjects demonstrate better patient survival at one year than Whites and non-Chinese Asians despite fewer live donors.


id: translation-250
author: Perz, Sarah; Suttle, Timothy; Sindhwani, Puneet
title: Management of Ureters Involved in Inguinal Hernias
date: 2018-10-17
pages: 6
extension: .pdf
mime: application/pdf
words: 3069
sentence: 160
flesch: 48
cache: cache/translation-250.pdf
txt: txt/translation-250.txt
summary:
  Ureteral inguinal hernia: an uncommon trap for general surgeons, BMJ Case Rep., 1, 1-5. 5. hernia CT ureteral stent herniorraphy ureteral calculus no ureteral injury renal insufficiency CT large hernia, renal failure ureteral stent herniorrhaphy no ureteral injury Perz et al. UTJMS 2018


id: translation-686
author: Akpunonu, Basil
title: Lung Cancer Metastasis to the Pituitary Gland
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 323
sentence: 15
flesch: 44
cache: cache/translation-686.pdf
txt: txt/translation-686.txt
summary:
  Here, we present a case of pituitary gland metastasis from underlying lung cancer in a patient presenting with a predominance of pituitary symptoms. Worsening pituitary symptoms with an enlarging pituitary mass and widespread metastases should alert consideration for pituitary metastasis and a search for a primary cancer site.


id: translation-772
author: Al-Tkrit, Amna
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 325
sentence: 18
flesch: 34
cache: cache/translation-772.pdf
txt: txt/translation-772.txt
title:
  Streptococcus intermedius - : An Uncommon Cause of Severe Pulmonary Infections in Immunocompetent Patients

summary:
  For both cases pleural fluid analysis was consistent with empyema, culture was positive for Streptococcus intermedius. Streptococcus intermedius is commonly identified in abscesses of brain or liver.


id: translation-347
author: Alkully, Turki; Hensley, Sandra ; Khuder, Sadik; Luke, Naveena; Ruzieh, Mohammed; Duggan, Joan
title: PICC line associated blood stream infections: an analysis of host and device factors
date: 2021-01-26
pages: 8
extension: .pdf
mime: application/pdf
words: 4526
sentence: 251
flesch: 55
cache: cache/translation-347.pdf
txt: txt/translation-347.txt
summary:
  A statistical anal- ysis of PICC CLABSI risk factors compared to matched con- trols was performed. There was significant correlation with PICC line infection and the following use of de-clotting agents (OR:0.22, 95% [CI:0.08-0.57], P=0.0009), complication after PICC line insertion (OR:4.22, 95%CI


id: translation-780
author: Noori, Zaid
title: Fatal Case of Invasive Pulmonary Aspergillosis Post COVID-19 Pneumonia Due to Aspergillus Niger
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 509
sentence: 24
flesch: 30
cache: cache/translation-780.pdf
txt: txt/translation-780.txt
summary:
  The prevalence of COVID-19 associated pulmonary aspergillosis (CAPA) ranged from 0 to 33%. However, only few cases of Aspergillus niger are reported in the literature.


id: translation-684
author: Renno, Anas
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 432
sentence: 18
flesch: 27
cache: cache/translation-684.pdf
txt: txt/translation-684.txt
title:
  Comparative Efficacy of Treatment Options for Prevention of Post-TIPS Hepatic Encephalopathy: : A Systematic Review and Network Meta-analysis

summary:
  May 5; 11(1):e1-e2 Comparative Efficacy of Treatment Options for Prevention of Post-TIPS Hepatic Encephalopathy: A Systematic Review and Network Meta-analysis Anas Renno1*, Zohaib Ahmed, MD1, Syeda Faiza Arif, MD1, Muhammad Aziz, MD1, Umair Iqbal, MD, Ahmad Nawaz, MD1 Wade Lee-Smith, MLIS2, Joyce Badal, MD1, Toseef Javaid, MD1, Ali Nawras, MD1, Mona Hassan, MD1, Sammy Saab, MD1 1Division of Gastroetnerology and Hepatology, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Department of University Libraries, The University of Toledo, Toledo, OH 43614 Therefore, we conducted a network meta-analysis to investigate the efficacy of multiple pharmacological regimens in preventing post-TIPS HE. Methods: A comprehensive search strategy to identify reports of studies of rifaximin use and post-TIPS hepatic encephalopathy was developed in Embase (Embase.com, Elsevier) by an experienced health sciences librarian [WL-S], using truncated keywords, phrases, and subject headings.


id: translation-750
author: Kammeyer, Joel
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 344
sentence: 19
flesch: 36
cache: cache/translation-750.pdf
txt: txt/translation-750.txt
title:
  Successful Administration of the Influenza Vaccine after Prior Serum Sickness in an HIV-Positive Patient

summary:
  Serum sickness reaction to influenza vaccination has not previously been described in HIV+ Serum sickness reactions to vaccination have previously been described (2-6), and are treated with steroids and removal of the offending agent (1).


id: translation-673
author: Halloran, Sean J
title: Hepatic Sarcoidosis Presenting as Cholestatic Liver Injury Exacerbated by Nitrofurantoin Use
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 329
sentence: 21
flesch: 34
cache: cache/translation-673.pdf
txt: txt/translation-673.txt
summary:
  We report a patient with hepatic sarcoidosis presenting as cholestatic liver injury exacerbated by nitrofurantoin use. This patient’s presentation was deemed most consistent with hepatic sarcoidosis.


id: translation-523
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 341
sentence: 17
flesch: 38
cache: cache/translation-523.pdf
txt: txt/translation-523.txt
author:
  DelCimmuto, Nicholas R; Al-Chalabi, Mustafa; Beran, Azizullah; Devarasetty, Pratyush Pavan; Mhanna, Asmaa; Sheikh, Ajaz

title:
  Clinical Characteristics, Management, and Outcomes of CLIPPERS:: A Comprehensive Systematic Review of 140 patients from 100 Studies

summary:
  May 05; 11(1):e1-e1 Clinical Characteristics, Management, and Outcomes of CLIPPERS: A Comprehensive Systematic Review of 140 patients from 100 Studies Nicholas R. DelCimmuto1*, Mustafa Al-Chalabi2, Azizullah Beran, MD3; Pratyush Pavan Devarasetty1, Asmaa Mhanna, MD3, Ajaz Sheikh, MD2 1College of Medicine and Life Sciences, The University of Toledo, Toledo, OH 43614 2Department of Neurology, The University of Toledo, Toledo, OH 43614 3Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 The University of Toledo Translation Journal of Medical Sciences Rheumatology Abstract, Department of Medicine Research Symposium UTJMS 2023


id: translation-671
author: Akpunonu, Basil
title: A Case of Rhabdomyolysis with Rigors
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 325
sentence: 13
flesch: 30
cache: cache/translation-671.pdf
txt: txt/translation-671.txt
summary:
  *Corresponding author: Basil.Akpunonu@utoledo.edu Published: 05 May 2023 Introduction: Rhabdomyolysis is a potential life- threatening condition caused by extensive skeletal muscle breakdown with leakage of toxic muscle contents into the circulation. The pathophysiologic hallmark of rhabdomyolysis regardless of etiology is increased free ionized calcium due to cellular energy depletion (ATP) or direct plasma membrane rupture and consequent intensified muscle contractility, mitochondrial dysfunction, and production of oxygen radicals.


id: translation-721
author: Salih, Ayman
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 345
sentence: 18
flesch: 49
cache: cache/translation-721.pdf
txt: txt/translation-721.txt
title:
  Knowledge, Attitude and Practices of Women Towards Breast Cancer in Arbaji Village, Gezira State, Sudan

summary:
  The aim was to assess the knowledge, attitude, and practice towards early breast cancer detection tools. Breast cancer is a worldwide disease resulting in many deaths.


id: translation-675
author: Aziz, Muhammad
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 368
sentence: 21
flesch: 48
cache: cache/translation-675.pdf
txt: txt/translation-675.txt
title:
  Safety and Effectiveness of Endoluminal Vacuum-Assisted Closure for Esophageal Defects: : Systematic Review and Meta-Analysis

summary:
  We performed a systematic review and pooled analysis of available literature to assess the safety and effectiveness of EVAC for esophageal defects. Methods: We queried PubMed/Medline, Embase, Cochrane, and Web of Science through September 25, 2020 to include all pertinent articles highlighting the safety and effectiveness profile of EVAC for esophageal defects.


id: translation-771
author: Al-Ataby, Harith
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 328
sentence: 21
flesch: 48
cache: cache/translation-771.pdf
txt: txt/translation-771.txt
title:
  Spontaneous Second Intercostal Artery Bleeding Complicated with Massive Hemothorax after Lower Limb Angioplasty Procedure

summary:
  Discussion: Spontaneous intercostal artery bleeding is extremely rare and reported in patients with underlying disorders, such as neurofibromatosis type 1, SLE, coarctation of aorta, Kawasaki disease, or Ehler-Danlos. We believe that our patient is the first reported case of spontaneous second intercostal artery bleeding in absence of underlying disorders.


id: translation-723
author: Sayeh, Wasef
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 392
sentence: 19
flesch: 54
cache: cache/translation-723.pdf
txt: txt/translation-723.txt
title:
  The Role of Tranexamic Acid Use in Reducing Mortality in Acute Upper GI Bleeding: : A Systemic Review and Meta-analysis

summary:
  May 5; 11(1):e1-e1 The Role of Tranexamic Acid Use in Reducing Mortality in Acute Upper GI Bleeding: A Systemic Review and Meta-analysis Wasef Sayeh, MD1*, Sami Ghazaleh, MD2, Azizullah Beran, MD1, Mohammad Safi, MD1, David Farrow, MD1, Sudheer Dhoop, MD1, Dipen Patel, MD, MBA1, Justin Chaung, MD1, Waleed Khokher, MD1, Omar Sajdeya, MD1, Sara Stanley; DO2, Muhammad Aziz, MD2, Yaseen Alastal, MD1 1Division of , Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of, Department of Medicine, The University of Toledo, Toledo, OH 43614 3Division of, Department of Medicine, The University of Toledo, Toledo, OH 43614 The primary outcome was the all-cause of mortality rate.


id: translation-420
author: Agnew, Matthew; Renno, Anas; Mahmood, Asif
title: Page Kidney: A Secondary Cause of Hypertension
date: 2021-03-03
pages: 3
extension: .pdf
mime: application/pdf
words: 1574
sentence: 78
flesch: 49
cache: cache/translation-420.pdf
txt: txt/translation-420.txt
summary:
  Page kidney can be suspected in patients with resis- tant hypertension and whose history reveals recent urologic manip- ulation. Page kidney is a rare cause of secondary hypertension in patients but can be considered in those with a recent history of nephrolithiasis and extracorporeal shock wave lithotripsy.


id: translation-594
author: Dimmerling, Taylor; Altattan, Mohamed; Altorok, Nezam
title: Relapsing Polychondritis: A Case Report of the Use of Adalimumab in Steroid Dependent Disease
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 172
sentence: 8
flesch: 16
cache: cache/translation-594.pdf
txt: txt/translation-594.txt
summary:
  May 05; 11(1):e1-e1 Relapsing Polychondritis: A Case Report of the Use of Adalimumab in Steroid Dependent Disease Taylor Dimmerling, MD1*, Mohamed Altattan, MD2, Nezam Altorok, MD2 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Rheumatology, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: taylor.dimmerling@utoledo.edu Published: 05 May 2023 Introduction: Conclusion: Biologic therapy with TNF-alpa inhibition can be considered in patients with refractory or steroid dependent relapsing polychondritis.


id: translation-737
author: Moussa, Rawan
title: The Effects of the Chemotherapy Drug Cisplatin on Cell Migration
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 257
sentence: 15
flesch: 37
cache: cache/translation-737.pdf
txt: txt/translation-737.txt
summary:
  We hypothesized that chemotherapy drugs displace IQGAP1 from cell junctions and increase cell migration and dissociation of renal cells. In mammalian cells, cell migration plays a crucial role such as promoting organ development, sperm and egg motility, and wound healing.


id: translation-620
author: Wang, Yongqing; Jun, John Y.
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 360
sentence: 21
flesch: 44
cache: cache/translation-620.pdf
txt: txt/translation-620.txt
title:
  Activation of the Transient Receptor Potential Ion Channel TRMP8 Mediates Upregulation 0f Profibrotic Genes, A New Pathway to Tissue Fibrosis

summary:
  In this study, we evaluated TRPM8 expression, the effects of TRPM8 activation on fibroblast (FB) fibrotic gene expression, and intracellular signaling. Conclusion: Functional TRPM8 is expressed in human dermal FBs and enhanced expression was observed in SSc FBs and skin.


id: translation-735
author: Kaur, Jasskiran
title: Predictors of 6-Month Mortality in Hospitalized COVID-19 Patients, : A Single-Institution Study
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 356
sentence: 15
flesch: 34
cache: cache/translation-735.pdf
txt: txt/translation-735.txt
summary:
  We included patients hospitalized with COVID-19 from University of Toledo Medical Center in Toledo, Ohio who were admitted within the timeframe of March 20,2020 to June 30, 2021. The University of Toledo Translation Journal of Medical Sciences UTJMS 2023


id: translation-769
author: Zhang, Shungang
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 319
sentence: 13
flesch: 30
cache: cache/translation-769.pdf
txt: txt/translation-769.txt
title:
  Disruption of CD40 Results in Significantly Attenuated Renal Inflammation Following Glycerol-Induced Acute Kidney Injury

summary:
  In addition, CD40 KO mice demonstrated significantly attenuated renal cortex gene expression of inflammatory markers IL1β, TGFβ1, and the fibrosis marker Col3a1 following AKI compared to wild-type (all p<0.05). We have also demonstrated significantly reduced pro-inflammatory and pro- fibrotic signaling in human CD40 KO renal proximal tubule epithelial cells.


id: translation-725
author: Shabpiray, Hoda
title: Typical Imaging Findings Of TB in an Old Patient with IPF
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 433
sentence: 20
flesch: 45
cache: cache/translation-725.pdf
txt: txt/translation-725.txt
summary:
  May 5; 11(1):e1-e1 Typical Imaging Findings Of TB in an Old Patient with IPF H. Shabpiray1*, G. Merugu1, M. khorsand Askari1, N. Aslam1 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: hoda.shabpiray@utoledo.edu Published: 05 May 2023 Introduction: The diagnosis of pulmonary TB should be suspected in patients with relevant clinical manifestations and epidemiologic factors, history of TB infection, known or possible TB exposure, past or present residence in or travel to an endemic area. Anchoring bias may lead to delay in TB diagnosis, especially with atypical clinical presentations and imaging findings for TB.


id: translation-773
author: Borchers, Elizabeth
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 358
sentence: 17
flesch: 43
cache: cache/translation-773.pdf
txt: txt/translation-773.txt
title:
  Pulse Versus Nonpulse Steroid Regimens in Patients with Coronavirus Disease 2019: : A Systematic Review and Meta-Analysis

summary:
  Therefore, we performed this meta-analysis to evaluate the role of PDS in COVID-19 patients compared to non-pulse steroids (NPDS). A Systematic Review and Meta-Analysis Elizabeth Borchers1*, Waleed Khokher2, Azizullah Beran2, Saffa Iftikhar2, Saif-Eddin Malhas2, Omar Srour2, Mohammed Mhanna2, Sapan Bhuta2, Dipen Patel2, Nithin Kesireddy2, Cameron Burmeister2, Ragheb Assaly1, Fadi Safi2 1Division of Pulmonology and Critical Care Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: Elizabeth.Borchers@rockets.utoledo.edu Published: 05 May 2023 Background: Systemic steroids are associated with reduced mortality in hypoxic patients with COVID- 19.


id: translation-727
author: Yassen, Mohammand
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 362
sentence: 12
flesch: 27
cache: cache/translation-727.pdf
txt: txt/translation-727.txt
title:
  The Efficacy of Cardiac Myosin Inhibitors Versus Placebo in Patients with Symptomatic Hypertrophic Cardiomyopathy

summary:
  Given the interplay between hypertrophic cardiomyopathy, elevated resting LVOT gradients (≥ 50 mm Hg) and heart failure and cardiovascular death, cardiac myosin inhibitors have recently emerged as a promising novel therapy to improve HCM-related outcomes by regulating myocardial relaxation and contractility, and thereby reducing intracavitary gradients. Conclusion: The use of cardiac myosin inhibitors in patients with symptomatic hypertrophic cardiomyopathy may confer both clinical and symptomatic benefits, at the possible expense of LV ejection fraction.


id: translation-731
author: Abdul-Aziz, Omar
title: Characterization of the Novel IQGAP1-Adrenergic Receptor Pathway in Lung Cancer
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 361
sentence: 15
flesch: 38
cache: cache/translation-731.pdf
txt: txt/translation-731.txt
summary:
  Our ongoing research will examine the effect of NE on protein levels and localizations in lung cancer and IQGAP1 mutant cells, as well as on the activity of signaling components downstream of IQGAP1. Next, we evaluated the effect of that dose on the gene expression levels of the two proteins and a downstream transcription factor, Nuclear Respiratory Factor 1 (NRF1), comparing response of lung cancer cells with normal lung epithelia by qRT-PCR.


id: translation-733
author: Gurung, Deepti
title: Probing Dynamics of 14-3-3: : A Potential Remedy for Pancreatic Cancer
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 354
sentence: 17
flesch: 36
cache: cache/translation-733.pdf
txt: txt/translation-733.txt
summary:
  *Corresponding author: Deepti.gurung@utoledo.edu Published: 05 May 2023 Introduction: Pancreatic cancer is the third-most-common cause of cancer-related deaths in the U.S. Drug development for pancreatic cancer has greatly advanced over the past decade. 14-3-3, therefore, is a potential anticancer target for the treatment of pancreatic cancer.


id: translation-450
author: Maier, Jacob; Rapport, Daniel ; McCormick, Alex; Lewis, Chandani
date: 2021-02-24
pages: 3
extension: .pdf
mime: application/pdf
words: 2151
sentence: 140
flesch: 55
cache: cache/translation-450.pdf
txt: txt/translation-450.txt
title:
  Oral Valproate Sodium as an Alternative to Benzodiazepine in the Treatment of Catatonia- A Case Report

summary:
  A literature search yielded a case of catatonia that was success- fully treated with sodium valproate, so we decided to treat him with oral sodium valproate. We present a case where oral sodium valproate was used successfully for both acute and long-term catatonic treatment.


id: translation-463
author: Menon, Bindu; Patel, Radha; Kovacs, Kelly; Prevette, Christopher ; Chen, Tian; Matus, Coral D
date: 2021-07-01
pages: 4
extension: .pdf
mime: application/pdf
words: 2832
sentence: 136
flesch: 51
cache: cache/translation-463.pdf
txt: txt/translation-463.txt
title:
  Integration of E-learning into the Physiology Education of Medical Students in their Pre-clinical Curriculum : E-learning in Medical Phyiology Education

summary:
  Once we have obtained more comprehensive data, it will provide more critical information about the utility of LMs in student learning. The new integrated method was introduced to the second-year (M2) class of medical students in their foundational science curriculum (class size, 177) during the gastrointestinal (GI) physiology sessions.


id: translation-521
author: Jonathan Doan; Dr. Irfan Sheikh; Ajaz Sheikh; Dr. Mehmood Rashid
date: 2022-12-20
pages: 4
extension: .pdf
mime: application/pdf
words: 2245
sentence: 104
flesch: 47
cache: cache/translation-521.pdf
txt: txt/translation-521.txt
title:
  Clinical Application and Initial Response of Seizures and Epilepsy in the Hospital Setting – An Educational Tool for Medical Students: Medical Student Clinical Epilepsy Education 

summary:
  Methods: 3rd year medical students rotating on the neurology clerkship at University of Toledo were divided into two groups - if they received a resident-led didactic lecture or not. Results: 3rd year medical students who received the resident-led didactic lecture on seizure and epilepsy clinical application and initial management scored higher on average on the survey, with statistical significance (p<0.05) seen when asked to clinically identify a seizure and how to record a seizure event in the hospital setting.


id: translation-415
author: Shao, Qin; Thompson, Gerard; Thompson, Amy
title: COVID-19 Risk Factor Identification based on Ohio Data
date: 2020-12-21
pages: 9
extension: .pdf
mime: application/pdf
words: 4319
sentence: 207
flesch: 68
cache: cache/translation-415.pdf
txt: txt/translation-415.txt
summary:
  According to the p- values in Table 5, the effects of age levels are significantly different, except for the rst two age levels, 0 - 19 and 20 - 29 for which mor- tality probabilities are not statistically significantly different. There is also growing evidence to suggest that while equal numbers of men and women develop COVID-19, when looking across age groups, males are more likely to die with the exception of 8 utdc.utoledo.edu/Translation Shao et al. the age group of 80+ where there are significantly more female than male deaths occurred.


id: translation-550
date: 2023-07-06
pages: 5
extension: .pdf
mime: application/pdf
words: 2354
sentence: 138
flesch: 49
cache: cache/translation-550.pdf
txt: txt/translation-550.txt
author:
  Sadry, Payam; Magsi, Rayan; Ahmed, Maahum; Amsdell, Jennifer; Derani, Talal; Mahfooz, Naeem; Sheikh, Ajaz

title:
  Symptomatic Intracranial Hypertension Secondary to Superior Vena Cava Thrombosis as the First Manifestation of Behçet’s Disease: ATYPICAL FIRST MANIFESTATION OF BEHCET’S

summary:
  Screening for large venous thrombosis using MRI/MRV and CTA in BD patients with elevated intracranial pressure is Figure 1. Some cases of young BD patients with cardiac involvement have been reported in geographical regions with high BD prevalence but are overall quite rare (2,11).


id: translation-361
author: Jankun, Jerzy
title: COVID-19 pandemic; transmembrane protease serine 2 (TMPRSS2) inhibitors as potential drugs.
date: 2020-04-24
pages: 5
extension: .pdf
mime: application/pdf
words: 4054
sentence: 259
flesch: 52
cache: cache/translation-361.pdf
txt: txt/translation-361.txt
summary:
  PAI-1 is hu- man in origin and engineered forms with an extended half-life were developed and could be an attractive addition to the ex- isting TMPRSS2 inhibitors. They also emphasize the importance of TMPRSS2 protease inhibition.


id: translation-739
author: Norris, Jordan
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 367
sentence: 17
flesch: 31
cache: cache/translation-739.pdf
txt: txt/translation-739.txt
title:
  Glioblastoma in Pregnant Patient with Pathologic and Exogenous Sex Hormone Exposure and Family History of High-Grade Glioma 

summary:
  Conclusion: Sex hormones and genetics likely exert influence on GBM development and progression that may compound with concurrence. May 5; 11(1):e1-e2 https://dx.doi.org/10.46570/utjms.vol11-2023-739 Haematology and Oncology Abstract, Department of Medicine Research Symposium Glioblastoma in Pregnant Patient with Pathologic and Exogenous Sex Hormone Exposure and Family History of High- Grade Glioma Jordan Norris, BS1*, Andrew Waack, BS1, Kathryn N. Becker, PhD1, Myles Keener, BS1, Jason L. Schroeder, MD2, Kevin Reinard, MD, Alistair Hoyt, MD, Danae Hamouda, MD1 1Division of Haematology and Oncology, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Department of Surgery, The University of Toledo, Toledo, OH 43614 *Corresponding author: Jordan.norris2@rockets.utoledo.edu Published: 05 May 2023 Introduction: Glioblastoma (GBM) incidence is higher in males, suggesting sex hormones may influence GBM tumorigenesis.


id: translation-72
author: Marco, Catherine A.; McGervey, Megan; Gekonde, Joan; Martin, Caitlin
title: Pain scores among ED patients: correlation with desire for pain medication
date: 2014-01-23
pages: 3
extension: .pdf
mime: application/pdf
words: 3210
sentence: 200
flesch: 61
cache: cache/translation-72.pdf
txt: txt/translation-72.txt
summary:
  Pain scores usually effectively predicted which pa- tients desired pain medications. There was not a significant difference in pain scores between pa- tients who desired pain medication and those who were undecided (Wilcoxon p=0.2; Table 2).


id: translation-408
author: Yahaya, Tajudeen; Oladele, Esther; Nnochiri, Kelechi; Abdullahi, Haliru; Nathaniel, Josephine
title: Genetic Susceptibility to Coronavirus Disease 19 (COVID-19): A Review
date: 2021-06-23
pages: 6
extension: .pdf
mime: application/pdf
words: 6160
sentence: 400
flesch: 60
cache: cache/translation-408.pdf
txt: txt/translation-408.txt
summary:
  When the patients were grouped according to blood types, individuals with type A had a higher chance of developing severe respiratory failure compared with type O (21). In another study, a retrospective cohort study of SARS-CoV-2 patients in three hospitals in China also associated the prevalence and severity of the virus with blood types.


id: translation-515
author: Lombardi, Conner; Glosser, Logan; Knauss, Hanna; Norwood, Teanya; Berry, Julia; Ekwenna, Obinna
date: 2021-11-22
pages: 5
extension: .pdf
mime: application/pdf
words: 4497
sentence: 316
flesch: 54
cache: cache/translation-515.pdf
txt: txt/translation-515.txt
title:
  Impact of Social Determinants of Health on Chronic Kidney Disease: A Review of Disparities in Renal Transplantation: Socioeconomic Impact on Kidney Transplant

summary:
  The five-year survival in patients with kidney transplant is 86%, compared to 53% in hemodialysis.(9) As such, kidney transplant has become a target for health incentives. To improve access to kidney transplants, there is a need to iden- tify and address factors outside of genetic predisposition that influ- ences ESRD treatment.


id: translation-741
author: Patel, Rayna
title: NF1 in Solid Tumors: : The Unknown Soldier of Tumor Suppressor Genes
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 241
sentence: 10
flesch: 34
cache: cache/translation-741.pdf
txt: txt/translation-741.txt
summary:
  However, the role of NF1 mutation in cancer has not been extensively studied, unlike other TSGs such as retinoblastoma (Rb), p53, Adenomatous Polyposis Coli (APC), or Phosphatase and Tensin Homolog (PTEN). Here we will discuss the molecular role of NF1 in cancer development and cancer-related cellular signaling.


id: translation-633
author: Abugharbyeh, Aya; Khuder, Sadik; Kahaleh, Bashar
title: Decreased Prevalence of Autoimmune Connective Tissue Diseases in Type 1 and Type 2 Diabetes
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 339
sentence: 17
flesch: 53
cache: cache/translation-633.pdf
txt: txt/translation-633.txt
summary:
  In patient with type 1 and type 2 diabetes mellitus (DM). Conclusion: The data demonstrates an inverse relation between SSc, lupus, and SS in patients with DM.


id: translation-627
author: Davis, Samantha
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 329
sentence: 20
flesch: 27
cache: cache/translation-627.pdf
txt: txt/translation-627.txt
title:
  IgA Vasculitis Associated with COVID-19 Infection Successfully Treated with Corticosteroid Regimen without Relapse

summary:
  Case: We report a 33-year-old male with COVID-19 infection two weeks before developing worsening palpable purpura for one week then severe abdominal pain, nausea, emesis, diarrhea, hematochezia, and arthralgia. Conclusion: This case demonstrates active COVID-19 infection precipitated biopsy-proven IgA vasculitis.


id: translation-635
author: Abrahamian, Andrew; Burmeister, Cameron; Hejeebu, Srini
title: Suspected Doxycycline Induced Acute Interstitial Nephritis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 321
sentence: 18
flesch: 25
cache: cache/translation-635.pdf
txt: txt/translation-635.txt
summary:
  The patient’s presentation led to a relatively broad differential for acute kidney injury (AKI), which included contrast-induced nephropathy, vancomycin-induced nephrotoxicity, and interstitial nephritis secondary to antibiotic use. Interstitial nephritis associated with doxycycline use is poorly described in the literature, which delayed cessation of suspected offending agent.


id: translation-638
author: Abuhelwa, Ziad
title: Midostaurin in Advanced Systemic Mastocytosis: A Systematic Review and Meta-analysis
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 387
sentence: 17
flesch: 40
cache: cache/translation-638.pdf
txt: txt/translation-638.txt
summary:
  The most common subtype of advanced SM was SM associated with hematological neoplasm (59%) followed by aggressive SM (23.1%). Methods: We systematically searched the following databases: PubMed/MEDLINE, Embase, and Cochrane through February 02, 2022, to include all studies that assessed the effect of midostaurin on clinical outcomes of patients with advanced SM.


id: translation-642
author: Marellapudi, Amulya
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 354
sentence: 15
flesch: 43
cache: cache/translation-642.pdf
txt: txt/translation-642.txt
title:
  Cardioprotective Effects of Paraoxanase 3 in a Dahl Salt-Sensitive Rat Model of Chronic Kidney Disease

summary:
  In female rats, by 8 weeks 100% mortality was observed in SS-Pon3 KO rats on high salt diet while no mortality was observed in SS rats on high salt. By 8 weeks, mortality was observed in 18.2% of male SS-Pon3 KO rats on high salt; no mortality was observed in male SS male rats on high salt.


id: translation-722
author: Sayeh, Wasef
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 397
sentence: 20
flesch: 44
cache: cache/translation-722.pdf
txt: txt/translation-722.txt
title:
  Full Thickness Versus Circular Peroral Myotomy in the Treatment of Esophageal Achalasia: : A Systematic Review and Meta-Analysis

summary:
  Recent studies have investigated full thickness myotomy as a possible alternative. A Systematic Review and Meta- Analysis Wasef Sayeh, MD1*, Sami Ghazaleh, MD2, Azizullah Beran, MD1, Mohammad Safi, MD1, Dipen Patel, MD, MBA1, Justin Chaung, MD1, Saif-Eddin Malhas, MD1, Amna Iqbal, MD1, Ziad Abuhelwa, MD1, Waleed Khokher, MD1, Omar Sajdeya, MD1, Anas Alsughayer, MD1, Anas Renno, MD2, Ajit Ramadugu, MD2, Ali Nawras; MD2 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Gastroenterology and Hepatology, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: wasef.sayeh@utoledo.edu Published: 05 May 2023 Introduction:


id: translation-736
author: Hamouda, Danae
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 323
sentence: 19
flesch: 53
cache: cache/translation-736.pdf
txt: txt/translation-736.txt
title:
  Immune Checkpoint Inhibitor Induced Hepatitis Injury: : Risk Factors, Outcomes, and Impact on Survival

summary:
  ICIH was more frequent in women (p=0.038), in patients treated with combination ICIs (p<0.001), and when given as first line therapy (p=0.018). Few studies have evaluated risk factors and outcomes of patients who develop ICI-induced hepatitis (ICIH).


id: translation-724
author: Shabpiray, Hoda
title: A case of Extra Mammary Paget’s disease in a Geriatric Patient
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 444
sentence: 27
flesch: 52
cache: cache/translation-724.pdf
txt: txt/translation-724.txt
summary:
  The patient is diagnosed with cutaneous invasive adenocarcinoma. A 67-year-old male with a history of renal cell cancer status post left nephrectomy, diabetes, HTN and COPD presented with complaint of fatigue and 40 Ibs weight loss in 2 months.


id: translation-738
author: Nigro, Anthony
title: Immunotherapeutic Interventions in Carcinoid Tumors
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 317
sentence: 23
flesch: 25
cache: cache/translation-738.pdf
txt: txt/translation-738.txt
summary:
  AdVince was tumoricidal to 100% of resected metastatic carcinoid tumor cells and delayed subcutaneous carcinoid tumor growth in mice. *Corresponding author: Anthony.Nigro@rockets.utoledo.edu Published: 05 May 2023 Introduction: Management of carcinoid tumors consists of pharmacological treatment and surgical resection.


id: translation-640
author: Breidenbach, Joshua
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 442
sentence: 15
flesch: 34
cache: cache/translation-640.pdf
txt: txt/translation-640.txt
title:
  Aerosolized Harmful Algal Bloom Toxin Microcystin-LR Induces Inflammatory Signaling in Human Airway Epithelial Cells

summary:
  May 05; 11(1):e1-e2 Aerosolized Harmful Algal Bloom Toxin Microcystin-LR Induces Inflammatory Signaling in Human Airway Epithelial Cells Joshua D. Breidenbach, MS1*, Benjamin W. French1, Tamiya T. Gordon1, Andrew L. Kleinhenz1, Apurva Lad, MS1, Robin C. Su, PhD1, James C. Willey, MD2, Jeffrey R. Hammersley, MD2, R. Mark Wooten, PhD3, Erin L. Crawford, MS1, Nikolai N. Modyanov, PhD4, Deepak Malhotra, MD, PhD5, Justin G. Teeguarden, PhD1, Steven T. Haller, PhD1, David J. Kennedy, PhD1 1Division of Cardiology, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Pulmonology and Critical Care Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 3Division of Infectious Diseases, Department of Medicine, The University of Toledo, Toledo, OH 43614 4Department of Physiology and Pharmacology, The University of Toledo, Toledo, OH 43614 5Division of Nephrology, Department of Medicine, The University of Toledo, Toledo, OH 43614 These blooms are often composed of outgrowths of cyanobacteria capable of producing the heptapeptide Microcystin-LR (MC- LR) which is a well-known hepatotoxin.


id: translation-644
author: Ranabothu, Meghana
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 360
sentence: 13
flesch: 34
cache: cache/translation-644.pdf
txt: txt/translation-644.txt
title:
  Paraoxanase-1 Modulates Cardiotonic Steroid Induced Cardiac Inflammation and Fibrosis in Dahl Salt Sensitive Model of Chronic Kidney Disease

summary:
  Methods: Dahl salt-sensitive wild type, PON1 knockout, and PON1 knockout rats that were treated with 3E9 anti-CTS monoclonal antibody were fed a high salt diet for five weeks to induce hypertensive renal disease and elevate CTS levels. *Corresponding author: Meghana.Ranabothu@rockets.utoledo.edu Published: 05 May 2023 Objective: Cardiotonic steroids (CTS) are known ligands of the Na+/K+-ATPase (NKA) and chronic elevations in volume expanded conditions such as hypertension and chronic kidney disease (CKD).


id: translation-621
author: Wang, Yongqing; Kahaleh, Bashar
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 344
sentence: 16
flesch: 35
cache: cache/translation-621.pdf
txt: txt/translation-621.txt
title:
  Downregulation of Microrna-126 in Scleroderma is Associated with Epigenetically Mediated Nitric Oxide Synthase Repression and Enhanced Platelet/Endothelial Interaction

summary:
  NOS3 expression levels were significantly reduced in SSc cells, Dnmt1 expression levels were significantly higher in SSc cells. Upregulation of MiR126 in SSc MVECs resulted in the reduction of Dnmt1 and upregulation of NOS3 expression levels, while the inhibition of MiR 126 expression levels in control MVECs resulted in decreased NOS3 levels and enhanced Dmnt1 levels.


id: translation-331
author: Alafyouni, Maisa; Huang, Derrick; Jones, Shanna; Kleiman, Scott
title: Acute Bilateral Ischemic Stroke in a Young Adult without risk factors
date: 2019-12-03
pages: 4
extension: .pdf
mime: application/pdf
words: 2405
sentence: 128
flesch: 55
cache: cache/translation-331.pdf
txt: txt/translation-331.txt
summary:
  Although both groups share identical modifiable risk factors, heart disease such as atrial fibrillation and diabetes mellitus is more prevalent in patents whereas dyslipidemia and smoking are more prevalent in younger stroke patients (10). The case highlights the need for a high index of suspicion in younger CVA patients whose greater potential for atypical presentations may compromise time-sensitive treatments.


id: translation-421
author: Giffen, Zane; Ezzone, Austin; Ekwenna, Obi
title: A Retrospective Cohort Analysis of Robotic Stapler Use in Robotic-Assisted Donor Nephrectomy
date: 2021-01-27
pages: 3
extension: .pdf
mime: application/pdf
words: 2538
sentence: 132
flesch: 54
cache: cache/translation-421.pdf
txt: txt/translation-421.txt
summary:
  Conclusions: Robotic stapler use is safe and effective in robotic-assisted donor nephrectomy, even in cases of complex renal hilar anatomy. Further research on prevalence of robotic stapler use is needed to quantify the asso- ciated complication rate.


id: translation-526
author: Lewis, Chandani; Brennan, Christine
date: 2023-07-06
pages: 4
extension: .pdf
mime: application/pdf
words: 2613
sentence: 180
flesch: 53
cache: cache/translation-526.pdf
txt: txt/translation-526.txt
title:
  “Clozapine & Valbenazine for Treatment of Tardive Cervical Dystonia: A Case Report”: Tardive Cervical Dystonia

summary:
  This case illustrates the potential for clozapine plus valbenazine to treat tardive cervical dystonia. In this case report we present a 29-year-old African American male with a history of paranoid schizophrenia who developed tardive cervical dystonia after exposure to second generation antipsychotics.


id: translation-734
author: Osman, Mahasin
title: The Dominant Negative IQGAP1(IR-WW) Domain as a Potential Therapy in Brain Cancer
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 240
sentence: 11
flesch: 32
cache: cache/translation-734.pdf
txt: txt/translation-734.txt
summary:
  Genetic mutant analysis in breast cancer cells has shown that the various domains of IQGAP1 have distinct effects on cell proliferation. These results are consistent with our previous findings in cervical cancer cells and present IQGAP1 as a clinical target in oncology.


id: translation-729
author: Yassen, Mohammad
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 288
sentence: 10
flesch: 30
cache: cache/translation-729.pdf
txt: txt/translation-729.txt
title:
  The Impact of Sacubitril / Valsartan Versus ACE/ARB Therapy on Functional Capacity in Heart Failure with Reduced Ejection Fraction

summary:
  Given the correlation between subjective, patient-oriented measures and objective outcomes (for example, perceived symptomatic benefits promoting medication compliance), we sought to investigate the effect of ARNIs on exercise capacity in a patient-defined manner. Methods: We performed a literature search using PubMed, Embase, and Cochrane Library from inception through May 2022 to assess the impact of Sacubitril/Valsartan versus ACE therapy on physical activity tolerance in patients with heart failure with reduced ejection fraction. Conclusion: The use of ARNI compared to standard ACE therapy confers no statistically significant improvement in functional capacity in patients with heart failure with reduced ejection fraction.


id: translation-726
author: Wang, Li
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 344
sentence: 18
flesch: 44
cache: cache/translation-726.pdf
txt: txt/translation-726.txt
title:
  A Case of Acute Myopericarditis in a Patient with Human Metapneumovirus (hMPV) Respiratory Infection

summary:
  With the rising popularity of RPP tests in recent years, the increasing detection of hMPV infections will shed more light on its association with myopericarditis. *Corresponding author: Li.Wang5@utoledo.edu Published: 05 May 2023 Human metapneumovirus (hMPV), a relatively newly isolated virus, has emerged as one of the most common pathogens implicated in respiratory tract infections worldwide.


id: translation-646
author: Sood, Ambika
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 388
sentence: 14
flesch: 28
cache: cache/translation-646.pdf
txt: txt/translation-646.txt
title:
  Paraoxanase 1 Regulation of Cardiac Inflammation and Fibrosis in a Dahl Salt-Sensitive Rat Model of Chronic Kidney Disease

summary:
  Results: RT PCR analysis of cardiac left ventricular tissue revealed an increase in the expression of natriuretic peptide A (p< 0.0001) and myosin heavy chain 7 (p< 0.0001), suggesting cardiac hypertrophy in SS-PON-1 KO male rats compared to controls (SS). Results are consistent with the echocardiography analysis and trichrome analysis indicating increased cardiac fibrosis in SS-PON-1 KO vs SS rats.


id: translation-740
author: Patel, Rayna
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 214
sentence: 7
flesch: 27
cache: cache/translation-740.pdf
txt: txt/translation-740.txt
title:
  Natural killer cells: a review of biology, : therapeutic potential and challenges in treatment of solid tumors

summary:
  We will review our current knowledge of NK cells’ biology, and highlight the challenges facing NK cell antitumor strategies in solid tumors. Owing to their ability to engage tumor targets without the need of specific antigen, the therapeutic potential of NK cells has been extensively explored in hematological malignancies.


id: translation-732
author: Abuhelwa, Ziad
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 498
sentence: 21
flesch: 41
cache: cache/translation-732.pdf
txt: txt/translation-732.txt
title:
  Hepatic Arterial Infusion Chemotherapy versus Trans-arterial Chemoembolization in Unresectable Hepatocellular Carcinoma: : A Systematic Review and Meta-Analysis

summary:
  The median PFS was significantly longer in the HAIC group, ranging from 5.5 to 9.6 months, vs. TACE, ranging from 1.5 to 5.4 months (HR 0.45, 95% CI 0.26-0.79, P=0.001, I2=84.6%). HAIC was associated with significantly higher ORR (RR 2.70, 95% CI 2.06-3.55, P<0.001, I2=10.1%) and DCR (RR 1.42, 95% CI 1.19-1.70, P<0.001, I2=54.5%) and substantially reduced PD (RR 0.55, 95% CI 0.40-0.75, P<0.001, I2=56.6%) compared to TACE.


id: translation-730
author: Zerihun, Kirubel
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 388
sentence: 16
flesch: 47
cache: cache/translation-730.pdf
txt: txt/translation-730.txt
title:
  Efficacy and Safety of Insulin Icodec Versus Glargine U100- A meta-analysis of randomized controlled trials

summary:
  Methods: We conducted a meta-analysis of randomized controlled trials that investigated the efficacy and safety of insulin icodec compared to glargine U100. From each clinical trial, we collected the number of patients who received icodec insulin and glargine U100.


id: translation-637
title: Primary Esophageal Extra-Gonadal Yolk Sac Tumor Metastasized to the Liver
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 354
sentence: 19
flesch: 46
cache: cache/translation-637.pdf
txt: txt/translation-637.txt
author:
  Abuhelwa, Ziad; Beran, Azizullah; Malhas, Saif-Eddin; Sayeh, Wasef; Sajdeya, Omar; Spencer, Caleb; Assaly, Ragheb

summary:
  Discussion: Primary gastrointestinal germ cell tumors have been very rarely reported in the literature. No reported case of primary esophageal yolk sac tumor (YST) has been published yet in the literature.


id: translation-688
author: Alharbi, Abdulmajeed
title: Bictegravir, Emtricitabine & Tenofovir Alafenamide-associated Acute Pancreatitis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 332
sentence: 15
flesch: 33
cache: cache/translation-688.pdf
txt: txt/translation-688.txt
summary:
  Healthcare providers should be aware of the unusual adverse event of Bictegravir, Emtricitabine, and Tenofovir alafenamide (Biktarvy) as a potential cause of pancreatitis in patients with Human Immunodeficiency Virus (HIV). Abdulaziz Aldhafeeri MD1, Nezam Altorok MD2 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Rheumatology, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: Abdulmajeed.Alharbi@utoledo.edu Published: 05 May 2023 Background: Bictegravir, Emtricitabine & Tenofovir alafenamide (Biktarvy) is now considered as the first line treatment for Human Immunodeficiency virus (HIV).


id: translation-634
author: Abdelrahman, Ahmad; Alharbi, Abdulmajeed; Nesheiwat, Zeid; Grande, Robert
title: Intermittent High Grade AV-Block and Atrial Flutter Associated with Lyme Carditis: : A Case Report
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 333
sentence: 22
flesch: 41
cache: cache/translation-634.pdf
txt: txt/translation-634.txt
summary:
  Lyme disease is the most common tick-borne infection caused by spirochetes in the Borreliacidal family. Lyme disease typically progresses in phases.


id: translation-639
author: Aradhyula, Vaishnavi
title: A Novel Lipidomics Approach to Predicting Pulmonary Hypertension in Human Heart Failure
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 358
sentence: 15
flesch: 36
cache: cache/translation-639.pdf
txt: txt/translation-639.txt
summary:
  Pulmonary venous and arterial serum samples were collected during right heart catheterization from 88 HFpEF patients without PH (control, n=40), HFpEF with isolated postcapillary PH (pc-PH, n=30), and HFpEF with combined post- and precapillary PH (cpc-PH, n=18). PGF2 alpha and 20-OH PGF2 alpha both pro- and anti-inflammatory molecules, were more significant predictors of HFpEF with cpc- PH compared to pc-PH (p=0.006).


id: translation-690
author: Ali, Aizaz
title: Renal Cell Carcinoma Metastasis to the Left Atrium
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 350
sentence: 18
flesch: 37
cache: cache/translation-690.pdf
txt: txt/translation-690.txt
summary:
  Given that there is no established algorithm for managing cardiac metastases from RCC, a surgical approach seems most feasible. In addition, affected patients are mostly asymptomatic and can present variably.


id: translation-692
author: Badal, Joyce
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 357
sentence: 17
flesch: 35
cache: cache/translation-692.pdf
txt: txt/translation-692.txt
title:
  Lithium-Induced Nephrogenic Diabetes Insipidus Self-Treated With Beer Potomania and Masquerading as Shock: : A Case Report

summary:
  Nephrogenic diabetes insipidus (NDI) is a known adverse effect from lithium use, commonly presenting as polyuria and polydipsia. We stopped lithium and initiated hypotonic fluids, amiloride, hydrochlorothiazide, and indomethacin.


id: translation-668
author: Ghazaleh, Sami
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 336
sentence: 18
flesch: 40
cache: cache/translation-668.pdf
txt: txt/translation-668.txt
title:
  Early Versus Delayed Minimally Invasive Intervention for Infected Pancreatic Necrosis - : A Systematic Review and Meta-Analysis

summary:
  However, early intervention was associated with a statistically significant higher risk of gastrointestinal fistula or perforation (RR 1.52, 95% CI 1.04 – 2.21, p = 0.03, I2 = 0%) and a longer hospital length of stay (MD 10.25 days, 95% CI 0.41 – 20.10, p = 0.04, I2 = 52%). Early intervention resulted in higher risk of gastrointestinal fistula or perforation and longer length of stay.


id: translation-643
author: Patel, Shivani C
title: Harmful Algal Bloom Toxin Microcystin-LR Induces Macrophage Inflammation of Lung Tissues
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 429
sentence: 16
flesch: 32
cache: cache/translation-643.pdf
txt: txt/translation-643.txt
summary:
  Results: Gene expression profiles of mice exposed to HAB toxin aerosols demonstrated a significant increase in the CD68 gene expressed by macrophages in C57BL/6J mice. The University of Toledo Translation Journal of Medical Sciences Cardiology Abstract, Department of Medicine Research Symposium UTJMS 2023


id: translation-696
author: Holtzapple, Zachary
title: Who Left the Dog Out (of the History)? - : Capnocytophage Canimorus Baceteremia Induced Sepsis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 189
sentence: 9
flesch: 41
cache: cache/translation-696.pdf
txt: txt/translation-696.txt
summary:
  - Capnocytophage Canimorus Baceteremia Induced Sepsis Zachary Holtzapple MD1*, Wilfred J. G. Ellis MD1 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: Zachary.Holtzapple@utoledo.edu Published: 05 May 2023 Capnocytophage canimorsus is a gram-negative rod bacterium that composes the microbial biome in the oral cavity of some canines and felines. The University of Toledo Translation Journal of Medical Sciences Internal Medicine Abstract, Department of Medicine Research Symposium UTJMS 2023


id: translation-641
author: French, Benjamin
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 345
sentence: 15
flesch: 36
cache: cache/translation-641.pdf
txt: txt/translation-641.txt
title:
  Harmful Algal Bloom Impacts on Human Health: An Analysis of National Emergency Department Data in the U.S. from 2016 to 2018

summary:
  We sought to determine trends and patterns in diagnostic codes relating to HAB exposures from the Healthcare Cost and Utilization Project's (HCUP) Nationwide Emergency Department Sample (NEDS). Methods: We analyzed HCUP NEDS data from years 2016 to 2018 as these represented the years in which complete data was available using the World Health Organization (WHO) International Classification of Diseases-10 diagnosis codes for HAB exposure.


id: translation-670
author: Ghazaleh, Sami
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 338
sentence: 19
flesch: 40
cache: cache/translation-670.pdf
txt: txt/translation-670.txt
title:
  Use of Smartphone Applications to Augment Colonoscopy Preparation Instructions and Effect on Quality of Colonoscopy Preparation and Adenoma Detection Rate – : A Systematic Review and Meta-Analysis

summary:
  Conclusion: Our meta-analysis demonstrated that the use of smartphone applications to augment colonoscopy preparation instructions improves the quality of colonoscopy preparation and adenoma detection rate. Eight studies reported adequate bowel preparation, which was significantly higher in patients who used smartphone applications compared with controls (RR 1.17, 95% CI 1.06 – 1.30, p < 0.003, I2 = 90%).


id: translation-694
author: Chinnam, Sahithi
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 305
sentence: 15
flesch: 42
cache: cache/translation-694.pdf
txt: txt/translation-694.txt
title:
  The Importance of Neuro-Imaging in Patients with Symptomatic Presentation of Both Cortical and Subcortical Dementia

summary:
  The University of Toledo Translation Journal of Medical Sciences Internal Medicine Abstract, Department of Medicine Research Symposium UTJMS 2023 May 5; 11(1):e1-e1 The Importance of Neuro-Imaging in Patients with Symptomatic Presentation of Both Cortical and Subcortical Dementia S Chinnam, DO1*, P Patel, DO1, J Creech, DO1 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614


id: translation-645
author: Soehnlen, Sophia
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 385
sentence: 14
flesch: 34
cache: cache/translation-645.pdf
txt: txt/translation-645.txt
title:
  Paraoxanase 1 Deletion Leads to Increased Cardiac Remodeling and Cardiac Fibrosis in a Dahl Salt-Sensitive Rat Model of Chronic Kidney Disease

summary:
  Results: SS-Pon1 KO male rats demonstrated a significantly increased relative cardiac wall thickness (0.77+/-0.05 vs. 0.58+/-0.02) and fractional shortening (0.62+/-0.02 vs. 0.53+/-0.01), as well as significantly increased mean velocity of circumferential fiber shortening (circ/s, 6.37+/-0.33 vs. 5.52+/- 0.17) and cardiac index (ml/min/kg, 184+/-18 vs. 136+/-11) vs age matched SS rats. Upon histological examination, heart sections of SS-Pon1 KO male rats showed a significant increase in fibrosis and heart-weight-to-body-weight ratio compared to the age matched SS rats.


id: translation-389
author: Kheireldin, Rowida; Imdad, Sameer; Ostwani, Waseem
date: 2020-08-13
pages: 4
extension: .pdf
mime: application/pdf
words: 2067
sentence: 126
flesch: 52
cache: cache/translation-389.pdf
txt: txt/translation-389.txt
title:
  TANGO-2 with Severe and Prolonged Rhabdomyolysis in a 2-year Old Male TANGO-2 with Severe and Prolonged Rhabdomyolysis in a 2-year Old Male with Human metapneumovirus Infection. A case report and literature review. : TANGO-2

summary:
  During a metabolic crisis, some patients may develop acute rhabdomyolysis. Rowida Kheireldin a Sameer Imdad a Waseem Ostwani b Coresponding author(s): waseem.ostwanimd@promedica.org aDivisions of Pediatrics, Department of Pediatrics, University of Toledo, College of Medicine and Life Sciences, Toledo, OH 43614, USA, and bDivisions of Critical Care Medicine, Department of Pediatrics University of Toledo College of Medicine and Life Sciences, Toledo, OH 43614, USA We report a unique case of prolonged acute rhabdomyolysis in a 2-year-old male with known TANGO-2 mutation with delayed peak in creatinine kinase levels secondary to human metapneu- movirus infection.


id: translation-551
author: Magsi, Rayan; Ryan, Casey; Sheikh, Ajaz; Noor, Mariam; Mahfooz, Naeem
title: Novel Gene Abnormality in Epilepsy with Myoclonic-Atonic Seizures (Doose Syndrome)
date: 2023-07-06
pages: 3
extension: .pdf
mime: application/pdf
words: 1950
sentence: 123
flesch: 56
cache: cache/translation-551.pdf
txt: txt/translation-551.txt
summary:
  [15] Joshi, C., Nickels, K., Demarest, S., et al. Results of an international Delphi consensus in epilepsy with myoclonic atonic seizures/Doose syndrome. Approximately 35-40% of first-degree relatives of patients also developed clinical seizures.


id: translation-332
author: Salari, MD, Bijan; Rospert, Daniel; Boyle, MD, Emmett; Sindhwani, MD, Puneet; Emmert, MD, Gregor
title: Metastatic Breast Cancer to the Bladder
date: 2020-05-06
pages: 3
extension: .pdf
mime: application/pdf
words: 1366
sentence: 80
flesch: 53
cache: cache/translation-332.pdf
txt: txt/translation-332.txt
summary:
  Occasion- ally, metastatic breast cancer can present itself with obstructive uropathy from a proposed retroperitoneal spread. We present a case of a 77 year old Caucasian female who was found to have acute urinary obstruction from metastatic breast cancer to the bladder.


id: translation-488
author: Eric Medrano; Jake Goliver
title: Suspected Compartment Syndrome and Rhabdomyolysis after “Pseudoephedrine” Use: A Case Report
date: 2021-08-18
pages: 3
extension: .pdf
mime: application/pdf
words: 1911
sentence: 103
flesch: 50
cache: cache/translation-488.pdf
txt: txt/translation-488.txt
summary:
  Although the most common cause of compartment syndromes are secondary orthopedic causes such as lower extremity fractures there are known docu- mented toxicological causes. However, it is incred- ibly rare to see an association with pseudoephedrine overdose and rhabdomyolysis and compartment syndrome.


id: translation-713
author: pena, clarissa
title: Ventricular Fibrillation Arrest after Blunt Chest Trauma in a 33-year-old Male, Commotio Cords?
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 344
sentence: 18
flesch: 44
cache: cache/translation-713.pdf
txt: txt/translation-713.txt
summary:
  We present a case in which ventricular fibrillation occurs in an older male athlete after blunt trauma. Case Presentation: A patient with no known medical history was brought to the emergency department after being found unconscious secondary to ventricular fibrillation after a soccer ball kick to the chest.


id: translation-698
author: Iqbal, Amna
title: Hepatitis C Screening in Pregnancy: : A Single Center Quality Improvement Experience
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 485
sentence: 17
flesch: 35
cache: cache/translation-698.pdf
txt: txt/translation-698.txt
summary:
  We conducted a quality improvement project in our hospital regarding Hepatitis C screening among pregnant women. Our objective was to assess compliance with CDC guideline recommendation regarding Hepatitis C screening in pregnant women and suggest ways to improve it.


id: translation-715
author: Royfman, Rachel
title: Worsening Pericardial Effusion Despite Intensive Hemodialysis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 280
sentence: 13
flesch: 32
cache: cache/translation-715.pdf
txt: txt/translation-715.txt
summary:
  Complications of end- stage renal disease can include pericarditis and pericardial effusion. Some patients are able to successfully complete peritoneal dialysis at home, which is more convenient.


id: translation-647
author: Waack, Andrew
title: Venous Stent Migration to the Heart: Case Report and Review of the Literature
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 337
sentence: 18
flesch: 43
cache: cache/translation-647.pdf
txt: txt/translation-647.txt
summary:
  We present a case of bilateral iliac vein stent migrations into the right ventricle and interlobar artery. Bilateral iliac vein stents were placed five years prior and a pacemaker six weeks prior.


id: translation-711
author: Patel, Neha
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 354
sentence: 16
flesch: 51
cache: cache/translation-711.pdf
txt: txt/translation-711.txt
title:
  Efficacy and Safety of Carotid Endarterectomy Versus Carotid Artery Stenting in Asymptomatic Severe Carotid Stenosis:: A Systematic Review and Meta-Analysis

summary:
  Most studies compare outcomes between procedures in symptomatic patients; however, there is limited data comparing CEA to CAS in asymptomatic severe CS. Methods: We performed a literature search using PubMed, Embase, and Cochrane Library from inception through September 2021 to investigate the efficacy and safety of CAS compared to CEA in patients with asymptomatic severe CS. In patients with severe CS, both carotid endarterectomy (CEA) and carotid artery stenting (CAS) carry procedural risks, however they can restore patency and significantly reduce long-term stroke risk.


id: translation-700
author: Iqbal, Amna
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 475
sentence: 21
flesch: 42
cache: cache/translation-700.pdf
txt: txt/translation-700.txt
title:
  Nosocomial vs Healthcare Associated vs Community Acquired SBP – : A Systematic Review and Meta-Analysis

summary:
  Number of N-SBP, HA-SBP and CA-SBP episodes, ascitic fluid culture results and previous SBP episode data was gathered. Spontaneous bacterial peritonitis (SBP) is a common complication in decompensated liver cirrhosis.


id: translation-702
author: Khader, Yasmin
title: Do Patients with Scleroderma Benefit from Surgical Treatment for Gastroesophageal Reflux?
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 351
sentence: 18
flesch: 49
cache: cache/translation-702.pdf
txt: txt/translation-702.txt
summary:
  Anti-reflux medications are still considered the first line treatment of GERD in SSc patients. We conducted this meta-analysis to assess for the benefit of surgery in treating GERD in SSc patients.


id: translation-522
date: 2022-12-20
pages: 6
extension: .pdf
mime: application/pdf
words: 2982
sentence: 226
flesch: 54
cache: cache/translation-522.pdf
txt: txt/translation-522.txt
author:
  Gifford, Connor; Norris, Jordan; Sheehan, Erin; Becker, Kathryn; Alexander, Christopher; Schroeder, Jason; Smithason, Saksith

title:
  Case Report: Cerebral Edema and Tonsillar Herniation Leading to Brain Death After Cocaine Use in a Patient with End-Stage Renal Disease

summary:
  Blood cocaine levels can range from 0.1 to 24 mg/L following a single insufflation, demonstrating its wide range of toxicity. We present the first known case of a non-compliant dialysis patient who suffers cerebral edema, tonsillar herniation, and brain death following cocaine use.


id: translation-706
author: Khokher, Waleed
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 375
sentence: 17
flesch: 47
cache: cache/translation-706.pdf
txt: txt/translation-706.txt
title:
  Pulse versus Non-pulse Steroid Regimens in Patients with Coronavirus Disease 2019: : A Systematic Review and Meta-Analysis

summary:
  A Systematic Review and Meta-Analysis W. Khokher, MD1*, A. Beran, MD1, S. Iftikhar, MD1, S. Malhas, MD1, O. Srour, MD1, M. Mhanna, MD1, S. Bhuta, MD1, D. Patel, MD1, N. Kesireddy, MD1, C. Burmeister, MD1, E. Borchers, MS41, R. Assaly, MD2, F. Safi, MD1 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: Waleed.Khokher@utoledo.edu Published: 05 May 2023 Introduction: Therefore, we performed this meta-analysis to evaluate the role of PDS in COVID-19 patients compared to non-pulse steroids (NPDS).


id: translation-708
author: Kloster, Alex
title: Heerfordt-Waldenstrom Syndrome: : A Case Report
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 341
sentence: 18
flesch: 44
cache: cache/translation-708.pdf
txt: txt/translation-708.txt
summary:
  05 May 2023 Background: Heerfordt-Waldenstrom Syndrome(HWS) is a variant of sarcoidosis, which presents with swelling of the Parotid or salivary glands, facial nerve paralysis and anterior uveitis. The incidence is rare, with only 6% of sarcoidosis patients having parotid gland enlargement, and 5% of patients with cranial nerve palsy.


id: translation-704
author: Khokher, Waleed
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 374
sentence: 13
flesch: 33
cache: cache/translation-704.pdf
txt: txt/translation-704.txt
title:
  Clinically Significant Gastrointestinal Bleeding Using Proton Pump Inhibitors or Histamine Type-2 Receptor Antagonists in Patients Intubated for Over 48 Hours: : A Systematic Review and Meta-Analysis

summary:
  Abuhelwa, MD1, S. Malhas, MD1, T. Saif, MD1, R. Assaly, MD2 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: Waleed.Khokher@utoledo.edu Published: 05 May 2023 Introduction: The use of stress ulcer prophylaxis (SUP) is routine in the intensive care unit (ICU) to prevent serious deleterious effects of gastrointestinal bleeding (GIB). The University of Toledo Translation Journal of Medical Sciences Internal Medicine Abstract, Department of Medicine Research Symposium UTJMS 2023


id: translation-691
author: Alqadi, Mohammad
title: Effect of Antiplatelet Medications on Critically Ill Patients with Pre-existing Atrial Fibrillation
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 339
sentence: 12
flesch: 31
cache: cache/translation-691.pdf
txt: txt/translation-691.txt
summary:
  *Corresponding author: Mohammad.Alqadi@utoledo.edu Published: 05 May 2023 Introduction: Limited data was found about the usage of antiplatelet medications on patients who previously diagnosed with atrial fibrillation (AF), and were critically ill and admitted to stepdown care unit (SDU) due to other acute conditions. Our goal to clarify the effect of antiplatelet medications on the adverse events (i.e., transfer to intensive care unit (ICU) or death), and the influence of the associated clinical factors.


id: translation-417
author: Jessica Allman; Mohamad Moussa; Shivam Shah; Madison Rectenwald; Casey Pollard; Jake Goliver
title: Virtual COVID-19 Clinical Teaching Session:: A Substitute for ‘Sheltered in Place’ MedicalStudents
date: 2020-11-19
pages: 5
extension: .pdf
mime: application/pdf
words: 3142
sentence: 161
flesch: 49
cache: cache/translation-417.pdf
txt: txt/translation-417.txt
summary:
  The ability to adapt in real time to changing clinical guidelines is a skill that clinical students need to emulate on their return to the clini- cal setting. While physicians, residents, and medical students would all benefit from hands-on training on the medical manage- ment and stabilization of COVID-19 patients, this is not feasible due to risk of transmission and spread of the virus.


id: translation-689
author: Alharbi, Abdulmajeed
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 327
sentence: 18
flesch: 42
cache: cache/translation-689.pdf
txt: txt/translation-689.txt
title:
  Vocal Cord Palsy and Neutropenia: : Unusual Presentation of B-12 Deficiency in Adult Patient, A Case Report

summary:
  This case highlights the fact that manifestations of vitamin B12 deficiency can be highly variable and underscores the need to keep this disorder on the differential diagnosis in a variety of clinical presentations. *Corresponding author: Abdulmajeed.Alharbi@utoledo.edu Published: 05 May 2023 Background: Vitamin B12 deficiency commonly causes megaloblastic anemia and rarely pancytopenia.


id: translation-520
title: pdf Limits to Neurosurgical Care for an Undocumented Immigrant in the United States: A Case Report
date: 2021-11-18
pages: 4
extension: .pdf
mime: application/pdf
words: 2791
sentence: 161
flesch: 49
cache: cache/translation-520.pdf
txt: txt/translation-520.txt
author:
  Keener, Myles; Sturges, Rebecca; Becker, Kathryn; Gifford, Connor; Alexander, Christopher; Schroeder, Jason; Smithason, Saksith

summary:
  Correspondingly, UIs report worse access to health care as well as poorer health out- comes compared with other populations in the US (7). Without legal access to health insurance, accessing health care in the US requires that undocumented immigrants personally absorb the costs of care or pursue free healthcare through either the emergency department or a free private clinic (3, 8).


id: translation-669
author: Akpunonu, Basil
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 324
sentence: 15
flesch: 24
cache: cache/translation-669.pdf
txt: txt/translation-669.txt
title:
  Bilateral Accessory (Aberrant) Renal Arteries Associated With Uncontrolled Hypertension—Role of Renin-Angiotensin-Aldosterone Antagonist Drugs for Treatment Goal: : A Case Report

summary:
  Conclusion: Accessory renal arteries could lead to perfusion abnormalities, contribute to or exacerbate maintenance and control of blood pressure. A computed tomographic angiography (CTA) and magnetic resonance angiography (MRA) showed accessory renal arteries in both the right and left kidneys.


id: translation-716
author: Rushdi, Hadeel I
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 559
sentence: 27
flesch: 33
cache: cache/translation-716.pdf
txt: txt/translation-716.txt
title:
  Mesenteric Mesothelial Cyst a Relatively Rare Complication of Peritoneal Dialysis and Intra-Abdominal Surgical Sequel, Case Presentation

summary:
  We present a case of a patient with multiple cysts in which simultaneous sampling of different lesions yielded a sterile result and heavy growth of MRSA pointing to need for multiple sampling. In this case, we believe that the cysts were complications of previous peritoneal dialysis treatments and peritonitis and recommend synchronous sampling of multiple cysts since benign and infected cysts can coexist.


id: translation-695
author: Holtzapple, Zachary
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 243
sentence: 12
flesch: 32
cache: cache/translation-695.pdf
txt: txt/translation-695.txt
title:
  Are Three Better than Two? – : Incidental Finding of Incomplete Cor Triatrium Dextrum during 2nd Trimester of Pregnancy

summary:
  *Corresponding author: Zachary.Holtzapple@utoledo.edu Published: 05 May 2023 Background: Cor triatriatum sinistrum is a type of congenital heart defect that occurs due to the left atrium being divided into two chambers by a fibromuscular septum. An even rarer subsection of this is cor triatriatum dextrum, in which the fibromuscular septum divides the right atrium.


id: translation-718
author: Sajdeya, Omar
title: Steroid-unresponsive Immune-mediated Hepatitis Induced by Durvalumab: : A Case Report
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 442
sentence: 21
flesch: 38
cache: cache/translation-718.pdf
txt: txt/translation-718.txt
summary:
  This requires careful monitoring of liver function tests in cancer patients on immune checkpoint inhibitors such as durvalumab, and demonstration of acute liver injury should be evaluated and managed promptly. Case Presentation: A 78-year-old female with a history of lung adenocarcinoma presented with abnormal liver function tests on routine screening after two cycles of durvalumab.


id: translation-720
author: Sajdeya, Omar
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 332
sentence: 14
flesch: 44
cache: cache/translation-720.pdf
txt: txt/translation-720.txt
title:
  The Rate of Adverse Events of Sodium-Glucose Cotransporter 2 Inhibitors: : A Meta-Analysis of Randomized Clinical Trials

summary:
  The University of Toledo Translation Journal of Medical Sciences Internal Medicine Abstract, Department of Medicine Research Symposium UTJMS 2023 We sought to assess the rate of adverse events with the use of SGLT2 inhibitors compared to placebo.


id: translation-693
author: Campbell, Drew
title: Exploring the Accuracy of the Medication Reconciliation Process on the Medical Floor
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 311
sentence: 15
flesch: 35
cache: cache/translation-693.pdf
txt: txt/translation-693.txt
summary:
  Of the charts where medication errors were found, 71.3% had three or more discrepancies. Our next focus should be on understanding why medication lists contain erroneous information because of added or missing medications.


id: translation-414
title: Does Patient Self-Awareness Predict Ankle Fractures?
date: 2021-01-28
pages: 5
extension: .pdf
mime: application/pdf
words: 3348
sentence: 170
flesch: 61
cache: cache/translation-414.pdf
txt: txt/translation-414.txt
author:
  Aouthmany, Shaza; Horn, Tymon ; Howe, Michelle; Kakish , Edward ; Kakish, Alana ; Pillai , Mahesh ; Jones, Corion

summary:
  How- ever, considering rising healthcare costs and radiation exposure, there is a need to improve the current yield of ankle X-rays and develop better tools to aid in assessing ankle fractures. The criteria for ordering ankle X-ray is a topic that warrants further conversation (6).


id: translation-462
author: Nguyen, Hanh ; Shao, Qin
date: 2021-09-01
pages: 11
extension: .pdf
mime: application/pdf
words: 4205
sentence: 225
flesch: 66
cache: cache/translation-462.pdf
txt: txt/translation-462.txt
title:
  Risk Identification and Prediction for COVID-19 Mortality: Risk Identification and Prediction for COVID-19 Mortality

summary:
  For example, how infectiousness of COVID-19 has been changing due to interventions (15), such as social distancing and curfew; it is possible that more and more eas- ily accessible tests have led to large case counts recently; more and more effective treatments could have been contributing to the reduc- Submitted: 03/23/2021, published: 08/31/2021. Case Fatality Rates rt and π t


id: translation-599
date: 2023-07-06
pages: 12
extension: .pdf
mime: application/pdf
words: 4395
sentence: 236
flesch: 56
cache: cache/translation-599.pdf
txt: txt/translation-599.txt
author:
  Heck, Holly; Tipton, Claire; Becker, Kathryn; Creeden, Justin; Schroeder, Jason; Larder, Cristin; Haak, Peterson; Pyles, Bryan; Eisenmann, Kathryn

title:
  Impact of COVID-19 on Clinical Productivity at the University of Toledo Medical Center Specialty Care Clinics

summary:
  % May -51.67% June -22.23% July -23.05% UTJMS 11(2):e1-e12 Heck et al 10.46570/utjms.vol11-2023-599 9 @2023 UTJMS Medicine Community Internal Medicine March -44.39% April -74.06 -44.21% April -87.79% May -35.83% June 28.33% July -1.01% Medicine Endocrinology March 12.82% April -20.80


id: translation-667
author: Ghazaleh, Sami
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 318
sentence: 19
flesch: 29
cache: cache/translation-667.pdf
txt: txt/translation-667.txt
title:
  Do Topical Corticosteroids Induce Histologic Remission and Improve Clinical Symptoms in Eosinophilic Esophagitis? - : A Systematic Review and Meta-Analysis

summary:
  Conclusion: Our meta-analysis demonstrated that topical corticosteroids were more effective than placebo in achieving histologic remission and improving clinical symptoms. Methods: We conducted a systematic review and meta-analysis of studies that investigated the efficacy and safety of topical corticosteroids compared with placebo in eosinophilic esophagitis.


id: translation-697
author: Hunyadi, Jonathan
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 410
sentence: 13
flesch: 20
cache: cache/translation-697.pdf
txt: txt/translation-697.txt
title:
  Antioxidant Therapy Restores Hepatic Metabolic Enzymes Altered by Exposure to Microcystin-LR in a Murine Model of Non-Alcoholic Fatty Liver Disease

summary:
  May 5; 11(1):e1-e2 Antioxidant Therapy Restores Hepatic Metabolic Enzymes Altered by Exposure to Microcystin-LR in a Murine Model of Non-Alcoholic Fatty Liver Disease Jonathan Hunyadi, BS1*, Apurva Lad, PhD1, Joshua D. Breidenbach, MS1, Jacob Connolly, UG1, Fatimah K. Khalaf, MBchB, PhD1, Prabhatchandra Dube, PhD1, Shungang Zhang, PhD1, Andrew L. Kleinhenz, BS1, David Baliu-Rodriguez, PhD1, Dragan Isailovic, PhD1, Terry Hinds, PhD, Deepak Malhotra MD, PhD2, Steven T. Haller PhD1, David J. Kennedy PhD1 1Division of Cardiovascular Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Nephrology, Department of Medicine, The University of Toledo, Toledo, OH 43614 8-OHDG levels in urine and protein carbonylation in liver, both markers of oxidative stress, were significantly downregulated upon antioxidant treatment after MC-LR exposure.


id: translation-714
author: Rostad, Kylie
title: Imipramine, Ulcerative Colitis and Linear Iga Bullous Dermatosis - : A Curious Triad
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 321
sentence: 18
flesch: 37
cache: cache/translation-714.pdf
txt: txt/translation-714.txt
summary:
  Linear IgA bullous dermatosis (LABD) is a rare autoimmune subepithelial vesiculobullous phenomenon caused by IgA antibodies against skin or mucosal basement membrane antigens. The temporal association of the imipramine initiation suggests that the medication may have acted as the trigger for LABD development during this initial flare of UC.


id: translation-701
author: Khader, Yasmin
title: Sarcoidosis and increased risk of Colorectal cancer: : A systematic review and Meta-analysis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 345
sentence: 17
flesch: 46
cache: cache/translation-701.pdf
txt: txt/translation-701.txt
summary:
  From each study, we collected the number of sarcoidosis patients with and without colorectal cancer. The aim of this study is to evaluate the correlation between sarcoidosis and the risk of colorectal cancer.


id: translation-710
author: Pasadyn, Vanessa
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 316
sentence: 15
flesch: 37
cache: cache/translation-710.pdf
txt: txt/translation-710.txt
title:
  Assessing Resident Confidence in Placing a Central Venous Catheter Before and After a Simulation-Based Training Course

summary:
  Before and After a Simulation-Based Training Course Vanessa Pasadyn, BA1*, Prajwal Hegde, BS1, Ola El Kebbi, MD1, Shaza Aouthmany, MD2 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Department of Emergency Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: vanessa.pasadyn@rockets.utoledo.edu Published: 05 The University of Toledo Translation Journal of Medical Sciences Internal Medicine Abstract, Department of Medicine Research Symposium UTJMS 2023


id: translation-699
author: Iqbal, Amna
title: Mantle Cell Lymphoma With GI Involvement Presenting as Bilateral Eyelid Swelling
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 463
sentence: 26
flesch: 46
cache: cache/translation-699.pdf
txt: txt/translation-699.txt
summary:
  We describe a case of MCL presenting as bilateral eyelid swelling. Mantle cell lymphoma (MCL) is a subtype of non-Hodgkin lymphoma accounting for about 5% of non-Hodgkin lymphomas.


id: translation-712
author: Patel, Neha
date: 2023-05-03
pages: 2
extension: .pdf
mime: application/pdf
words: 380
sentence: 16
flesch: 39
cache: cache/translation-712.pdf
txt: txt/translation-712.txt
title:
  Efficacy and Safety of Dual Antiplatelet Therapy Versus Direct Oral Anticoagulant Following Left Atrial Appendage Closure: : A Systematic Review and Meta-Analysis

summary:
  The rates of DRT (RR 4.82, 95% CI 0.60-38.89, P=0.14), ischemic stroke (RR 1.23, 95% CI 0.38-4.05, P=0.73), and major bleeding (RR 1.34, 95% CI 0.50-3.65, P=0.56) were numerically lower in the DOAC group compared to DAPT group, although the differences did not reach statistical significance. Current guidelines recommend oral anticoagulant for 45 days, followed by dual antiplatelet therapy (DAPT) for 6 months.


id: translation-707
author: Khokher, Waleed
title: Utility of Midodrine During the Recovery Phase of Shock: : A Systematic Review and Meta-Analysis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 302
sentence: 12
flesch: 46
cache: cache/translation-707.pdf
txt: txt/translation-707.txt
summary:
  There was no significant difference in total duration of IVV use, IVV weaning time, ICU LOS, hospital LOS, or adverse events between the two groups. May 5; 11(1):e1-e1 Utility of Midodrine During the Recovery Phase of Shock: A Systematic Review and Meta-Analysis W. Khokher, MD1*, S. Iftikhar, MD1, A. Beran, MD1, C. Burmeister, MD1, S. Malhas, MD1, S. Malik, MD1, O. Srour, MD1, A. Abrahamian, MD1, A. Alharbi, MD1, N. Kesireddy, MD1, T. Saif, MD1, R. Assaly, MD2 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614


id: translation-717
author: Sajdeya, Omar
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 323
sentence: 19
flesch: 44
cache: cache/translation-717.pdf
txt: txt/translation-717.txt
title:
  Efficacy and Safety of Intravascular Lithotripsy in the Treatment of Calcified Peripheral Artery Disease: : A Systematic Review and Meta-Analysis

summary:
  IVL delivery success rate, pooled mean of acute lumen gain, minimal lumen diameter (MLD), and residual stenosis. Data regarding IVL clinical utility for PAD remain sparse.


id: translation-709
author: Pasadyn, Vanessa
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 352
sentence: 14
flesch: 38
cache: cache/translation-709.pdf
txt: txt/translation-709.txt
title:
  Applications of Inhalational Nitrous Oxide in Patients as an Alternative to Traditional Narcotics and Sedation Agents in the Emergency Department

summary:
  This is the case of a 76-year-old woman who received nitrous oxide as analgesia for a shoulder reduction in the emergency department (ED). The goal of discussing this case is to emphasize the accessibility, efficacy, and safety of using nitrous oxide as a sedation agent in place of narcotics in the ED.


id: translation-705
author: Khokher, Waleed
title: Inhaled Pulmonary Vasodilators in COVID-19 Infection: : A Systematic Review and Meta-Analysis
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 353
sentence: 17
flesch: 49
cache: cache/translation-705.pdf
txt: txt/translation-705.txt
summary:
  The pre-IPVD P/F ratios were significantly lower compared to post-IPVD, but there was no significant difference between pre- and post-IPVD PEEP and lung compliance. *Corresponding author: Waleed.Khokher@utoledo.edu Published: 05 May 2023 Introduction: Inhaled pulmonary vasodilators (IPVD) have been previously studied in patients with non-coronavirus disease-19 (COVID-19) related acute respiratory distress syndrome (ARDS).


id: translation-719
author: Sajdeya, Omar
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 282
sentence: 17
flesch: 52
cache: cache/translation-719.pdf
txt: txt/translation-719.txt
title:
  Racial Differences in Hypercholesterolemia Prevalence: : A Cross-sectional Study Using 2017-2018 National Health and Nutrition Examination Survey Data

summary:
  May 5; 11(1):e1-e1 Racial Differences in Hypercholesterolemia Prevalence: A Cross-sectional Study Using 2017-2018 National Health and Nutrition Examination Survey Data Omar Sajdeya, MD1, Mohammad Safi, MD1, Ziad Abuhelwa, MD1, Wasef Sayeh MD1, Ragheb Assaly, MD2 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 AA had a 24 % reduced risk of HCL diagnosis than whites after adjusting for age, Body Mass Index (BMI), diabetes, hypertension, and smoking; OR


id: translation-703
author: Khader, Yasmin
date: 2023-05-03
pages: 1
extension: .pdf
mime: application/pdf
words: 357
sentence: 14
flesch: 44
cache: cache/translation-703.pdf
txt: txt/translation-703.txt
title:
  Predictors of Remission in Rheumatoid Arthritis Patients Treated with Biologics: : A Systematic Review and Meta-Analysis

summary:
  We included all studies that used a multivariate model to assess for the predictors of remission in RA patients treated with biologics. May 5; 11(1):e1-e1 Predictors of Remission in Rheumatoid Arthritis Patients Treated with Biologics: A Systematic Review and Meta- Analysis Yasmin Khader, MD1*, A. Beran, MD1, S. Ghazaleh, MD2, S. Devis, MD1, N. Altorok, MD3 1Division of , Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of, Department of Medicine, The University of Toledo, Toledo, OH 43614 3Division of, Department of Medicine, The University of Toledo, Toledo, OH 43614


id: translation-319
author: Yahaya, Tajudeen
title: Role of Epigenetics in the Pathogenesis and Management of Type 2 Diabetes Mellitus
date: 2019-12-02
pages: 10
extension: .pdf
mime: application/pdf
words: 9750
sentence: 826
flesch: 59
cache: cache/translation-319.pdf
txt: txt/translation-319.txt
summary:
  Starvation can modify placenta epigenome through gene methylation or modification of miRNAs associated with genes necessary for fetal development, nutrient transfer, and disease pre- vention (94). An experiment performed by Kameswaran et al.


# url

id: translation-104
domain: www.healthypeople.gov
url:
  http://www.healthypeople.gov/2020/topics-objectives/topic/lesbian-gay-bisexual-and-transgender-health?topicid=25


id: translation-104
domain: iom.nationalacademies.org
url:
  http://iom.nationalacademies.org/reports/2011/the-health-of-lesbian-gay-bisexual-and-transgender-people.aspx


id: translation-408
domain: theconversation.com
url:
  https://theconversation.com/your-genes-could-determine-whether-thecoronavirus-puts-you-in-the-hospital-and-were-starting-to-unravel-which-onesmatter-137145


id: translation-408
domain: primaryimmune.org
url:
  https://primaryimmune.org/about-primary-immunodeficiencies/specificdisease-types/innate-immune-defects


id: translation-408
domain: cen.acs.org
url:
  https://cen.acs.org/biologicalchemistry/infectious-disease/genetic-study-suggests-peoples-blood/98/i23


# ent

id: translation-759
sid: 18
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-759 https://dx.doi.org/10.46570/utjms.vol11-2023-759 mailto:victoria.soewarma@rockets.utoledo.edu


id: translation-656
sid: 9
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-656 mailto:muhammad.aziz@utoledo.edu https://dx.doi.org/10.46570/utjms.vol11-2023-656


id: translation-104
sid: 124
eid: 1
type: PERSON
entity:
  http://iom.nationalacademies.org/reports/2011/the-health-of-lesbian-gay-bisexual-and-transgender-people.aspx shukla  et  al.


id: translation-743
sid: 13
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-743 https://dx.doi.org/10.46570/utjms.vol11-2023-743 mailto:abdulaziz.aldhafeeri@utoledo.edu


id: translation-767
sid: 11
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-767 https://dx.doi.org/10.46570/utjms.vol11-2023-767 mailto:dhilhani.faleel@rockets.utoledo.edu


id: translation-751
sid: 13
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-751 https://dx.doi.org/10.46570/utjms.vol11-2023-751 mailto:katherine.esser@rockets.utoledo.edu


id: translation-756
sid: 21
eid: 1
type: NORP
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-756 https://dx.doi.org/10.46570/utjms.vol11-2023-756 https://dx.doi.org/10.46570/utjms.vol11-2023-756


id: translation-672
sid: 17
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-672 https://dx.doi.org/10.46570/utjms.vol11-2023-672 mailto:sean.halloran@rockets.utoledo.edu


id: translation-723
sid: 16
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-723 https://dx.doi.org/10.46570/utjms.vol11-2023-723 mailto:wasef.sayeh@utoledo.edu


id: translation-269
sid: 29
eid: 2
type: PERSON
entity:
  https://orcid.org/0000-0002-5036-7623 https://orcid.org/0000-0002-8815-0008 https://orcid.org/0000-0002-5790-783x


id: translation-521
sid: 44
eid: 4
type: ORG
entity:
  https://toledouw.iad1.qualtrics.com/jfe/form/sv_77mo0wknpga4olm https://toledouw.iad1.qualtrics.com/jfe/form/sv_77mo0wknpga4olm 10.46570


id: translation-752
sid: 18
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-752 https://dx.doi.org/10.46570/utjms.vol11-2023-752 mailto:joel.kammeyer@utoledo.edu


id: translation-199
sid: 247
eid: 3
type: PERSON
entity:
  ortiz http://scientific.thomsonreuters.com/imgblast/jcrfullcovlist-2014.pdf http://2013.atcmeeting.org/abstract-information


id: translation-741
sid: 9
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-741 https://dx.doi.org/10.46570/utjms.vol11-2023-741 mailto:rayna.patel@rockets.utoledo.edu


id: translation-621
sid: 14
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-621 https://dx.doi.org/10.46570/utjms.vol11-2023-621 mailto:yongquing.wang2@utoledo.edu


id: translation-730
sid: 13
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-730 https://dx.doi.org/10.46570/utjms.vol11-2023-730 mailto:kirubel.zerihun@utoledo.edu


id: translation-690
sid: 18
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-690 https://dx.doi.org/10.46570/utjms.vol11-2023-690 mailto:aizaz.ali@utoledo.edu


id: translation-647
sid: 17
eid: 1
type: NORP
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-647 https://dx.doi.org/10.46570/utjms.vol11-2023-647 mailto:andrew.waack@rockets.utoledo.edu


id: translation-688
sid: 14
eid: 1
type: PRODUCT
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-688 https://dx.doi.org/10.46570/utjms.vol11-2023-688 mailto:abdulmajeed.alharbi@utoledo.edu


id: translation-692
sid: 15
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-692 https://dx.doi.org/10.46570/utjms.vol11-2023-692 mailto:joyce.badal@utoledo.edu


id: translation-695
sid: 11
eid: 1
type: ORG
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-695 https://dx.doi.org/10.46570/utjms.vol11-2023-695 mailto:zachary.holtzapple@utoledo.edu


id: translation-711
sid: 17
eid: 1
type: ORG
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-711 https://dx.doi.org/10.46570/utjms.vol11-2023-711 mailto:neha.patel@utoledo.edu


id: translation-639
sid: 13
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-639 https://dx.doi.org/10.46570/utjms.vol11-2023-639 mailto:vaishnavi.aradhyula@rockets.utoledo.edu


id: translation-699
sid: 20
eid: 1
type: PRODUCT
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-699 https://dx.doi.org/10.46570/utjms.vol11-2023-699 mailto:amna.iqbal@utoledo.edu https://dx.doi.org/10.46570/utjms.vol11-2023-699


id: translation-719
sid: 13
eid: 1
type: ORG
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-719 https://dx.doi.org/10.46570/utjms.vol11-2023-719 mailto:omar.sajdeya@utoledo.edu


id: translation-701
sid: 14
eid: 1
type: ORG
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-701 https://dx.doi.org/10.46570/utjms.vol11-2023-701 mailto:yasmin.khader@utoledo.edu


id: translation-705
sid: 14
eid: 1
type: PERSON
entity:
  https://dx.doi.org/10.46570/utjms.vol11-2023-705 https://dx.doi.org/10.46570/utjms.vol11-2023-705 mailto:waleed.khokher@utoledo.edu


# pos

id: translation-408
sid: 260
tid: 3
pos: NOUN
token:
  https://primaryimmune.org/about-primary-immunodeficiencies/specificdisease-types/innate-immune-defects

lemma:
  https://primaryimmune.org/about-primary-immunodeficiencies/specificdisease-types/innate-immune-defect


