The University of Toledo Translation Journal of Medical Sciences Rheumatology Abstract, Department of Medicine Research Symposium UTJMS 2023 May 05; 11(1):e1-e1 Relapsing Polychondritis: A Case Report of the Use of Adalimumab in Steroid Dependent Disease Taylor Dimmerling, MD1*, Mohamed Altattan, MD2, Nezam Altorok, MD2 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Rheumatology, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: taylor.dimmerling@utoledo.edu Published: 05 May 2023 Introduction: Relapsing polychondritis is a rare chronic immune mediated disease characterized by inflammation in cartilaginous structures. The disease has traditionally been managed with systemic glucocorticoids and immunosuppressive agents such as methotrexate, cyclophosphamide, and mycophenoloate. Case Presentation: A 54 year old male with relapsoing polychondritis characterized by bilateral conjunctivitis and chondritis of the ear. The addition of adalimumab aided in tapering of high dose steroids after attempts with immunosuppressive agents were unsuccessful. Conclusion: Biologic therapy with TNF-alpa inhibition can be considered in patients with refractory or steroid dependent relapsing polychondritis. https://dx.doi.org/10.46570/utjms.vol11-2023-594 https://dx.doi.org/10.46570/utjms.vol11-2023-594 mailto:taylor.dimmerling@utoledo.edu