The University of Toledo Translation Journal of Medical Sciences 
Gastroenterology Abstract, Department of Medicine Research Symposium UTJMS 2023 May 05; 11(1):e1-e1 

Analysis of Demographic and Staging 
Characteristics in Patients with Colorectal 
Cancer Using the SEER Registry 
M. Devanaboyina, M41*, M. Bailey, M41, N. Kahlon, MD1, D. Hamouda, MD1 

1Division of  Haematology and Oncology, Department of Medicine, The University 
of Toledo, Toledo, OH 43614 

*Corresponding author: Monika.Devanaboyina@rockets.utoledo.edu

Published: 05 May 2023 

Screening for colorectal cancer (CRC) was previously started at age 50, with recent guidelines 
suggesting age 45 for earlier detection. CRC incidence data from NCI’s SEER registry was utilized for 
this study. Data from 2014-2018 was analyzed for ages 50-64, 64-74, and 75+. Localized, regional and 
distant metastasis were coded in the database. The incidence of CRC increased with age where ages 75+ 
had the highest incidence at 211.8 per 100,000, compared to 70.7 for ages 50-64. In the age group of 
75+, the incidence of localized CRC was 70.1 (95% CI: 69.2-71.0) and regional CRC was 69.2 (68.4-
70.1) which was not statistically significant. Female patients have a lower chance of presenting with 
CRC at 59.5, 107.6, 192.1 for the age groups 50-64, 65-74, and 75+ respectively, whereas male 
counterparts have rates of 82.7, 152.9, and 240.2. White males had statistically significant higher odds of 
localized compared to regional cancer in all age groups.  Asian females showed no difference in 
incidence of local and regional disease for ages 50-74.  For ages 75+, the incidence of regional disease at 
54.6 (51.3-58.1) was much higher than local disease at 45.3 (42.3- 48.5). Of note, Asian females aged 
50-64, Hispanic females ages 65 and older, and Black and White females ages 75+ were equally likely 
to present with local or regional disease. Ensuring equitable access to screening may be beneficial in 
improving cancer-related mortality in certain demographics. This analysis was limited to incidence, and 
future studies with presentation at diagnosis could be insightful.

https://dx.doi.org/10.46570/utjms.vol11-2023-658 

https://dx.doi.org/10.46570/utjms.vol11-2023-658
mailto:Monika.Devanaboyina@rockets.utoledo.edu