The University of Toledo Translation Journal of Medical Sciences 
Gastroenterology Abstract, Department of Medicine Research Symposium UTJMS 2023 May 05; 11(1):e1-e1 

Metastatic Renal Cell Carcinoma to the Descending Colon 
Presenting as Recurrent Hematochezia 

Sudheer Dhoop1*, Justin Chuang1, Azizullah Beran1, Anas Renno1, Sarah Stanley1, 
Ahmad Zohaib2, Yaseen Alastal2, Thomas Sodeman2

1Division of Internal Medicine , Department of Medicine, The University of Toledo, 
Toledo, OH 43614 
2Division of Gastroenterology and Hepatology, Department of Medicine, The 
University of Toledo, Toledo, OH 43614 

*Corresponding author: Sudheer.dhoop@utoledo.edu

Published: 05 May 2023 

Renal Cell Carcinoma (RCC) metastasis to the colorectal region is a rare occurrence. This report 
documents a case of an individual with solitary metastasis of RCC to the descending colon presenting 
with recurrent hematochezia. Per literature review, it is the first case of metastasis to the descending 
colon after negative diagnostic colonoscopy less than a year prior. Management of the patient’s 
hematochezia was challenging given poor surgical candidacy, no option for palliative radiation given 
non-visualization of the lesion on CT, and no target was present for IR guided embolization. The 
patient’s rectal bleeding was partially improved with cessation of his Apixaban indicated for atrial 
fibrillation stroke prophylaxis. Our case demonstrates that interval metastasis should always be on the 
differential for persistent GI bleeding in the setting of RCC and it highlights challenges in management 
of hematochezia related to colorectal metastasis of RCC. 

https://dx.doi.org/10.46570/utjms.vol11-2023-659 

https://dx.doi.org/10.46570/utjms.vol11-2023-659
mailto:Sudheer.dhoop@utoledo.edu