The University of Toledo Translation Journal of Medical Sciences Internal Medicine Abstract, Department of Medicine Research Symposium UTJMS 2023 May 5; 11(1):e1-e1 Racial Differences in Hypercholesterolemia Prevalence: A Cross-sectional Study Using 2017-2018 National Health and Nutrition Examination Survey Data Omar Sajdeya, MD1, Mohammad Safi, MD1, Ziad Abuhelwa, MD1, Wasef Sayeh MD1, Ragheb Assaly, MD2 1Division of Internal Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 2Division of Pulmonary and Critical Care Medicine, Department of Medicine, The University of Toledo, Toledo, OH 43614 *Corresponding author: Omar.Sajdeya@utoledo.edu Published: 05 May 2023 Introduction: African Americans (AA) have a 20% higher risk of CVD death than Whites. Treating hypercholesterolemia (HCL) is paramount in CVD primary prevention. Some evidence showed that AA have a lower risk of HCL compared to whites. Methods: A cross-sectional study using the 2017-18 National Health and Nutrition Examination Survey data. Logistic regression analysis was used to compare the prevalence of diagnosed HCL in AA and whites aged 18-80 years old. Serum total cholesterol (TC) and high-density lipoprotein (HDL) levels were compared by multiple linear regression. Results: Among 2549 participants, 51.7% were females, and 63.4% were white. The mean (SD) age was 51.6 (19.1) years. AA had a 24 % reduced risk of HCL diagnosis than whites after adjusting for age, Body Mass Index (BMI), diabetes, hypertension, and smoking; OR [95%CI]= 0.767 [0.621, 0.923]. There was no difference in TC level (p=0.7242), while HDL was higher among AA (p<0.0001, β=3.83), adjusting for age, gender, BMI, smoking, diabetes, education level, and use of cholesterol medications. Conclusion: Consistent with some evidence, AA had a lower prevalence of HCL diagnosis and higher HDL levels. https://dx.doi.org/10.46570/utjms.vol11-2023-719 https://dx.doi.org/10.46570/utjms.vol11-2023-719 mailto:Omar.Sajdeya@utoledo.edu