The University of Toledo Translation Journal of Medical Sciences 
UTJMS 2023 May 5; 11(1):e1-e2 

https://dx.doi.org/10.46570/utjms.vol11-2023-735 

Haematology and Oncology Abstract, Department of Medicine Research Symposium 

Predictors of 6-Month Mortality in 
Hospitalized COVID-19 Patients, A Single-
Institution Study 

Jasskiran Kaur BS21*, Navkirat Kahlon MD, MPH12, Sishir Doddi BS22, Cameron 
Burmeister MD, MS22, Taha Sheikh, MD3, Ziad Abuhelwa, MD22, Aya 
Abugharbyeh, MD1, Ragheb Assaly, MD4, William Barnett, MS2, Danae M. 
Hamouda, MD1 

1Division of Haematology and Oncology, Department of Medicine, The University 
of Toledo, Toledo, OH 43614 
2Division of Internal Medicine, Department of Medicine, The University of Toledo, 
Toledo, OH 43614 
3Department of Neurology, The University of Toledo, Toledo, Ohio 43614 
4Division of Pulmonary and Critical Care Medicine, Department of Medicine, The 
University of Toledo, Toledo, OH 43614 

*Corresponding author: jasskiran.kaur@rockets.utoledo.edu

Published: 05 May 2023 

Background:  Much of the data relating to post-acute COVID-19 infection morbidity and mortality risk 
is ninety-day data; however, less is known about longer term outcomes of mortality.   

Objectives: Our objective is to determine predictors of 6-month mortality on admission in hospitalized 
COVID-19 patients.  

Methods: This is a single-institution, retrospective study. We included patients hospitalized with 
COVID-19 from University of Toledo Medical Center in Toledo, Ohio who were admitted within the 
timeframe of March 20,2020 to June 30, 2021. Two groups were created based on the mortality outcome 
at 6 months from COVID-19 positive testing: survivors and non-survivors. The clinical variables or 
outcomes and laboratory values were compared using non-parametric methods due to the small sample 
size and non-normality of the data. Either the Mann-Whitney U-test for continuous variables or the 
Fisher’s exact test for categorical variables was used for statistical analysis.  

Results: Lactate dehydrogenase (LDH) (p=0.032) and D-dimer levels (p=0.019) were significantly 
higher in non-survivors on admission than in survivors. Demographic factors, comorbid conditions, and 
other laboratory data did not differ significantly between survivors and non-survivors.   

https://dx.doi.org/10.46570/utjms.vol11-2023-735
mailto:jasskiran.kaur@rockets.utoledo.edu


https://dx.doi.org/10.46570/utjms.vol11-2023-735  UTJMS 11(1):e1-e2    

https://dx.doi.org/10.46570/utjms.vol11-2023-735  2 ©2023 UTJMS  
 

  
 

Conclusion: Increased LDH and D-dimer levels on admission were found to predict 6-month mortality 
in hospitalized COVID-19 patients. 

  

https://dx.doi.org/10.46570/utjms.vol11-2023-735
https://dx.doi.org/10.46570/utjms.vol11-2023-735