Upsala J Med Sci 91: 223-224, 1986 New Seralyzer Compared to Routine Techniques in Clinical Chemistry Bertel Berg, Bengt Olsson and Nils Tryding Department of Clinicaf Chemistry, Central Hospital, Kristianstad, Sweden New Seralyzer (AMES) is a reflectometer designed mainly for serum and blood analyses with solid-phase chemistry (reagent strips). We have compared Seralyzer with the routine methods of our hospital labora- tory for 10 components, especially the two recently introduced tests for potassium and theophylline. Serum and blood samples were taken at random from the routine series f o r blind analysis with the New Seralyzer using well-trained personnel. Conclusion: Under optimal conditions the New Seralyzer instrument gave good accuracy and precision for S-Potassium and S-Theophylline. ( S e e Figures) F o r the other components results were often good, but sometimes accuracy and precision problems occurred (especially for serum enzymes). ( S e e Table) 1. S-K Seralyzer Eppendorf 2. S-THEOPHYUINE Seralyzer Cobas Bio "-140 y - I 01 x f0.09 r-0,957 "-34 y - I 00 x + 3 0 r=0.994 223 Ne w Se ra ly ze r (S L ) co mp ar ed t o ro ut in e te ch ni qu es ( RT ) in c li ni ca l ch em is tr y Co mp on en t N Ro ut in e te ch ni qu e Co nc en tr at io n Y= a+ bX cv cv cv (A T) X= RT Be tw ee n- me th od Wi th in -m et ho d Qu al it y co nt - Ho sp it al l ab or at or y Y= Se ra ly ze r RT /S er al yz er RT tr ol p ro gr am fo r we st er n Sw ed en S- K+ S- Th eo ph yl li ne S- Cr ea ti ni ne 5- AS AT S- Bi li ru bi n S- CK B- He mo gl ob in S- Ch ol es te ro l 14 0 34 13 8 28 39 26 89 41 Fl am e ph ot om et ry E M 1 T Ja ff 6 ki ne ti c SC E Di az o me th od SC E Co ul te r S + Ch ol es te ro l ox id as e me di an a 41 mm ol /l 0. 09 55 p mo l/ l 3. 0 95 p mo l/ l -6 .3 (> 0. 6) l. lk ka t/ l 0. 09 12 k mo l/ l -2 .0 1. 5 pk at /l -0 .0 3 13 5 g/ 1 0. 54 6. 2 mm ol /l 1. 21 b 1. 01 1 . oo 1. 12 0. 95 1. 07 1 . I6 0. 97 0. 89 r 0. 95 7 0. 99 4 0. 98 5 0. 98 6 0. 97 0 0. 99 1 0. 97 5 0. 92 1 3. 7 6. 3 8. 5 8. 2 11 .7 14 .9 2. 7 1 .I me di an Me di an 1. 2 2. 1 3. 1 -_ _ 2. 7 5. 4 2. 7 5. 4 2. 8 6. 7 2. 8 13 .2 0. 83 2. 1 2. 6 3. 7 S- Tr ig ly ce ri de s 41 Gl yc er ol k in as e 1. 9 mm ol /l 0. 07 1. 05 0. 99 3 6. 0 2. 8 7. 3 S- Ur at e 39 Ur ic as e 37 0 km ol /l 30 0. 89 0. 98 2 4. 9 2. 0 5. 2