U J All Final for WEB.pdf 811Vol. 10 | No. 1 | Winter 2013 |U R O LO G Y J O U R N A L Multicystic Renal Cell Carcinoma A Rare kidney Tumor in Children Dogan Atilgan,1 Nihat Uluocak,1 Fikret Erdemir,1 Bekir Suha Parlaktas,1 Resit Dogan Koseoglu,2 Ozgur Boztepe1 Keywords: kidney, neoplasms, cysts, child, nephrectomy INTRODUCTION R It is (2) - ond reported case of MCRCC in a child in English literature. CASE REPORT Lindau disease. - Corresponding Author: Dogan Atilgan, MD Gaziosmanpasa Üniversitesi Tıp Fakültesi, Üroloji AD 60100 Tokat, Turkey Tel: +90 533 312 9667 Fax: +90 356 212 9417 E-mail: datilgan@msn.com Received November 2009 Accepted January 2010 1 Department of Urology, Faculty of Medicine, Gaziosmanpasa Univer- sity, Tokat, Turkey 2 Department of Pathology, Faculty of Medicine, Gaziosmanpasa Uni- versity, Tokat, Turkey CASE REPORT 812 | Case Report nous pyelography revealed a right hydronephrotic kidney With the pre-operative diagnosis of hydronephrosis and a - - the specimen consisted of one kidney and attached perirenal - tortions in renal contours. Sectioning revealed multilocular necrotic, granular material. The uninvolved normal renal - locular cystic lesion (Figure 2). According to Fuhrman nuclear grading scheme, the nuclear - DISCUSSION Childhood cancers are much less common than adult can- cers. Leukemia and brain and spinal cord tumors are the most common type of cancers found in children. Other in- tumor, muscle or bone cancers, lymphoma, and RCC. In (3) Although RCCs may include cystic or solid structures, cystic - The av- Abdominal pain, hematuria, and fever are the most com- mon symptoms of CRCC. Even if palpable mass occurs (6) Multilocu- - Figure 1. Computed tomography showing a heterogeneous cystic lesion in the lower pole of the right kidney. Figure 2. The cystic tumoral formation with multilocular appear- ance is seen in macroscopic section. The normal kidney tissue is seen in a small area in the upper part. 813Vol. 10 | No. 1 | Winter 2013 |U R O LO G Y J O U R N A L Multicystic Renal Cell Carcinoma | Atilgan et al Multicystic RCC is also an unusual entity in children and reported previously in the literature.(7) Because of the rar- - ing pathologic features, natural history, clinical behavior, and prognosis remain uncertain. There are no treatment protocols agreed upon for pediatric MCRCC due to lim- - lescent or adult patients in the literature. These tumors are not radiosensitive, and chemotherapy results have been - phrectomy. it seems that MCRCC has better prognosis than non cystic RCC. - should be performed, especially in younger patients and in feasible intra-operatively. literature that MCRCC has better prognosis, malignant po- tential of this disease should be considered and manage- ment should be handled according to this point. - taken into account in the differential diagnosis of the kidney - CONFLICT OF INTEREST None declared. Figure 3. Histolological sections revealed multiple cysts seper- ated by fibrous hypocellular septa. Small papillary structures are seen among cystic areas. The cysts are filled with necrotic mate- rial (Hematoxylin and Eosin stain, ×10). Figure 4. Papillary structures included true fibrovascular cores, and lining cells had mild nuclear pleomorphism and hyperchro- masia. 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