Hrev_master Veins and Lymphatics 2018; volume 7:7627 [page 68] [Veins and Lymphatics 2018; 7:7627] Novel heterogeneous stiffness for dynamic compression reconstruction Rong Liu Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hum Hom, Kowloon, Hong Kong SAR Abstract Compression therapy is the recom- mended non-pharmaceutical choice for edema and ulcers treatment through deliv- ering static or dynamic pressure dosages to the affected legs. The traditional compres- sion modalities were prone to generate peak or uneven cutaneous pressure around anatomic geometries, leading to ischemia or deficient pressure delivery as well as discomfort or high non-compliance in clin- ical practice. The aim of this study was to reconstruct compression exertion through novel designed heterogeneous three- dimensional knitting structures and stiff- ness control to avoid sustained peak pres- sure but enhance muscular pumping action. The new heterogeneous structures integrate yielding and non-yielding elastic design via advanced tension controlled weft-knitting technologies to carter for anatomic mor- phologies and pressure requirements of the target users. The study indicated that the hybrid ratios of elasticity and their segmen- tal proportions significantly influence cuta- neous pressure profile. The new heteroge- neous structures can generate hybrid DSI in compression shells with customized figura- tions. The designed heterogeneous stiffness reconstructed compression around the lower limbs with reduction of cutaneous pressure at anterior tibia bone crest by 2.0%-9.6% (P<0.05) while increased those at posterior gastrocnemius regions by 9.3- 34.6% (P<0.05), resulting in more rational- ly pressure profiles around lower limb but maintaining degressive gradient from distal to proximal lower limb. The novel com- pression structures also present positive wearing feedback in our on-going clinical wear trials, which contribute to promote pressure function and user’s compliance in practice. Correspondence: Rong Liu, Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hum Hom, Kowloon, Hong Kong SAR. E-mail: rong.liu@polyu.edu.hk Conference presentation: International Compression Club (ICC) Meeting, Paris, 2017. This work is licensed under a Creative Commons Attribution 4.0 License (by-nc 4.0). ©Copyright R. Liu, 2018 Licensee PAGEPress, Italy Veins and Lymphatics 2018; 7:7627 doi:10.4081/vl.2018.7627 No n- co mm er cia l u se on ly