id	author	title	date	pages	extension	mime	words	sentence	flesch	summary	cache	txt
cord-017585-0llgr357	Chappell, Mark C.	Role of ACE, ACE2 and Neprilysin in the Kidney	2007		.txt	text/plain	7586	205	28	Braz Enhanced renal immunocytochemical expression of ANG-(1-7) and ACE2 during pregnancy Elevated blood pressure and heart rate in human renin receptor transgenic rats Angiotensin II and its receptors in the diabetic kidney Effect of reduced angiotensin-converting enzyme gene expression and angiotensin-converting enzyme inhibition on angiotensin and bradykinin peptide levels in mice Effects of neutral endopeptidase inhibition and combined angiotensin converting enzyme and neutral endopeptidase inhibition on angiotensin and bradykinin peptides in rats Differential regulation of angiotensin peptide levels in plasma and kidney of the rat Newly recognized components of the Renin-Angiotensin system: potential roles in cardiovascular and renal regulation Prolyl oligopeptidase is involved in release of the antifibrotic peptide Ac-SDKP Angiotensin-(1-7) is an endogenous peptide in the rat brain: evidence for differential processing of angiotensin peptides Processing of angiotensin peptides by NG108-15 neuroblastoma X glioma hybrid cell line Metabolism of angiotensin-(1-7) by angiotensin converting enzyme Angiotensin-(1-7) in hypertension Release of angiotensin-(1-7) from the rat hindlimb: influence of angiotensin-converting enzyme inhibition Pathways of angiotensin-(1-7) metabolism in the kidney Omapatrilat treatment is associated with increased ACE-2 and angiotensin-(1-7) in spontaneously hypertensive rats Estrogen or the AT1 antagonist olmesartan reverses the development of profound hypertension in the congenic mRen2.Lewis rat Novel aspects of the renal renin-angiotensin system: angiotensin-(1-7), ACE2 and blood pressure regulation Estrogen and salt sensitivity in the female mRen(2).Lewis rat Hydrolysis of angiotensin peptides by human angiotensin I-converting enzyme and the resensitization of B 2 kinin receptors Angiotensin-(1-7) downregulates the angiotensin II type 1 receptor in vascular smooth muscle cells Angiotensin-(1-7) reduces renal angiotensin II receptors through a cylocoxygenase dependent pathway Angiotensin-converting enzyme 2 is an essential regulator of heart function N-domain specific substrate and C-domain inhibitors of angiotensin converting enzyme ACE2 gene transfer attenuates hypertension-linked pathophysiological changes in the SHR RXP 407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites A novel angiotensin-converting enzymerelated carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9 New mass spectrometric assay for angiotensin-converting enzyme 2 activity Potentiation of bradykinin by angiotensin-(1-7) on arterioles of spontaneously hypertensive rats studied in vivo Characterization of angiotensin-(1-7) in the urine of normal and essential hypertensive subjects Effects of omapatrilat on the renin angiotensin system in salt sensitive hypertension Vasopeptidase inhibition and angiotensin-(1-7) in the spontaneously hypertensive rat Effect of angiotensin converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin converting enzyme 2 -7) forming enzymes and receptors Advances in biochemical and functional roles of angiotensin converting enzyme 2 and angiotensin-(1-7) in the regulation of cardiovascular function Distinct roles for Ang II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes Roles of the two active sites of somatic angiotensin-converting enzyme in the cleavage of angiotensin I and bradykinin: insights from selective inhibitors Membrane-associated zinc peptidase families: comparing ACE and ACE2 Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme Potential mechanisms and physiologic actions of intracellular angiotensin II Intrarenal AT 1 receptor and ACE binding in ANG II-induced hypertensive rats Postovariectomy hypertension is linked to increased renal AT1 receptor and salt sensitivity Angiotensin I-converting enzyme isoforms (high and low molecular weight) in urine of premature and full-term infants Renin increases mesangial cell transforming growth factor-B1 matrix proteins through receptormediated, angiotensin II-independent mechanisms Angiotensin II AT1 receptors regulate ace2 and angiotensin-(1-7) expression in aorta of spontaneously hypertensive rats Contribution of angiotensin II internalization to intrarenal angiotensin II levels in rats Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system Evidence that prostaglandins mediate the antihypertensive actions of angiotensin-(1-7) during chronic blockade of the renin-angiotensin system Effect of angiotensin II blockade on a new congenic model of hypertension derived from transgenic Ren-2 rats Mineralocorticoid receptor blocker increases angiotensin-converting enzyme 2 activity in congestive heart failure patients ACE2 activity is increased in monocytederived macrophages from prehypertensive subjects Aldosterone enhances renin expression in juxtaglomerular cells Expression of angiotensinogen mRNA and protein in angiotensin II-dependent hypertension CK2 phosphorylates the angiotensinconverting enzyme and regulates its retention in the endothelial cell plasma membrane Omapatrilat and Enalapril in Patients With Hypertension: The Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) Trial Differential tissue and enzyme inhibitory effects of the vasopeptidase inhibitor omapatrilat in the rat Tumor necrosis factor-a convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-Co-V) receptor, angiotensin-converting enzyme-2 (ACE2) Moreover, in an animal model of tissue-depleted ACE that preserves circulating levels of the enzyme, renal Ang II is significantly reduced (Modrall et al 2003) 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