id	sid	tid	token	lemma	pos
cord-301856-71syce4n	1	1	key	key	ADJ
cord-301856-71syce4n	1	2	:	:	PUNCT
cord-301856-71syce4n	1	3	cord-301856	cord-301856	NOUN
cord-301856-71syce4n	1	4	-	-	PUNCT
cord-301856-71syce4n	1	5	71syce4n	71syce4n	NOUN
cord-301856-71syce4n	1	6	authors	author	NOUN
cord-301856-71syce4n	1	7	:	:	PUNCT
cord-301856-71syce4n	1	8	domínguez	domínguez	NOUN
cord-301856-71syce4n	1	9	-	-	PUNCT
cord-301856-71syce4n	1	10	andrés	andré	NOUN
cord-301856-71syce4n	1	11	,	,	PUNCT
cord-301856-71syce4n	1	12	jorge	jorge	NOUN
cord-301856-71syce4n	1	13	;	;	PUNCT
cord-301856-71syce4n	1	14	netea	netea	PROPN
cord-301856-71syce4n	1	15	,	,	PUNCT
cord-301856-71syce4n	1	16	mihai	mihai	PROPN
cord-301856-71syce4n	1	17	g.	g.	PROPN
cord-301856-71syce4n	1	18	title	title	PROPN
cord-301856-71syce4n	1	19	:	:	PUNCT
cord-301856-71syce4n	1	20	impact	impact	NOUN
cord-301856-71syce4n	1	21	of	of	ADP
cord-301856-71syce4n	1	22	historic	historic	ADJ
cord-301856-71syce4n	1	23	migrations	migration	NOUN
cord-301856-71syce4n	1	24	and	and	CCONJ
cord-301856-71syce4n	1	25	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	1	26	processes	process	NOUN
cord-301856-71syce4n	1	27	on	on	ADP
cord-301856-71syce4n	1	28	human	human	ADJ
cord-301856-71syce4n	1	29	immunity	immunity	NOUN
cord-301856-71syce4n	1	30	date	date	NOUN
cord-301856-71syce4n	1	31	:	:	PUNCT
cord-301856-71syce4n	1	32	2019	2019	NUM
cord-301856-71syce4n	1	33	-	-	SYM
cord-301856-71syce4n	1	34	11	11	NUM
cord-301856-71syce4n	1	35	-	-	SYM
cord-301856-71syce4n	1	36	27	27	NUM
cord-301856-71syce4n	1	37	journal	journal	NOUN
cord-301856-71syce4n	1	38	:	:	PUNCT
cord-301856-71syce4n	1	39	trends	trend	VERB
cord-301856-71syce4n	1	40	immunol	immunol	NOUN
cord-301856-71syce4n	1	41	doi	doi	PROPN
cord-301856-71syce4n	1	42	:	:	PUNCT
cord-301856-71syce4n	1	43	10.1016	10.1016	NUM
cord-301856-71syce4n	1	44	/	/	SYM
cord-301856-71syce4n	1	45	j.it.2019.10.001	j.it.2019.10.001	PROPN
cord-301856-71syce4n	1	46	sha	shall	AUX
cord-301856-71syce4n	1	47	:	:	PUNCT
cord-301856-71syce4n	2	1	doc_id	doc_id	X
cord-301856-71syce4n	2	2	:	:	PUNCT
cord-301856-71syce4n	2	3	301856	301856	NUM
cord-301856-71syce4n	2	4	cord_uid	cord_uid	PROPN
cord-301856-71syce4n	2	5	:	:	PUNCT
cord-301856-71syce4n	2	6	71syce4n	71syce4n	NOUN
cord-301856-71syce4n	2	7	the	the	DET
cord-301856-71syce4n	2	8	evolution	evolution	NOUN
cord-301856-71syce4n	2	9	of	of	ADP
cord-301856-71syce4n	2	10	mankind	mankind	NOUN
cord-301856-71syce4n	2	11	has	have	AUX
cord-301856-71syce4n	2	12	constantly	constantly	ADV
cord-301856-71syce4n	2	13	been	be	AUX
cord-301856-71syce4n	2	14	influenced	influence	VERB
cord-301856-71syce4n	2	15	by	by	ADP
cord-301856-71syce4n	2	16	the	the	DET
cord-301856-71syce4n	2	17	pathogens	pathogen	NOUN
cord-301856-71syce4n	2	18	encountered	encounter	VERB
cord-301856-71syce4n	2	19	.	.	PUNCT
cord-301856-71syce4n	3	1	the	the	DET
cord-301856-71syce4n	3	2	various	various	ADJ
cord-301856-71syce4n	3	3	populations	population	NOUN
cord-301856-71syce4n	3	4	of	of	ADP
cord-301856-71syce4n	3	5	modern	modern	ADJ
cord-301856-71syce4n	3	6	humans	human	NOUN
cord-301856-71syce4n	3	7	that	that	PRON
cord-301856-71syce4n	3	8	ventured	venture	VERB
cord-301856-71syce4n	3	9	out	out	ADP
cord-301856-71syce4n	3	10	of	of	ADP
cord-301856-71syce4n	3	11	africa	africa	PROPN
cord-301856-71syce4n	3	12	adapted	adapt	VERB
cord-301856-71syce4n	3	13	to	to	ADP
cord-301856-71syce4n	3	14	different	different	ADJ
cord-301856-71syce4n	3	15	environments	environment	NOUN
cord-301856-71syce4n	3	16	and	and	CCONJ
cord-301856-71syce4n	3	17	faced	face	VERB
cord-301856-71syce4n	3	18	a	a	DET
cord-301856-71syce4n	3	19	large	large	ADJ
cord-301856-71syce4n	3	20	variety	variety	NOUN
cord-301856-71syce4n	3	21	of	of	ADP
cord-301856-71syce4n	3	22	infectious	infectious	ADJ
cord-301856-71syce4n	3	23	agents	agent	NOUN
cord-301856-71syce4n	3	24	,	,	PUNCT
cord-301856-71syce4n	3	25	resulting	result	VERB
cord-301856-71syce4n	3	26	in	in	ADP
cord-301856-71syce4n	3	27	local	local	ADJ
cord-301856-71syce4n	3	28	adaptations	adaptation	NOUN
cord-301856-71syce4n	3	29	of	of	ADP
cord-301856-71syce4n	3	30	the	the	DET
cord-301856-71syce4n	3	31	immune	immune	ADJ
cord-301856-71syce4n	3	32	system	system	NOUN
cord-301856-71syce4n	3	33	for	for	ADP
cord-301856-71syce4n	3	34	these	these	DET
cord-301856-71syce4n	3	35	populations	population	NOUN
cord-301856-71syce4n	3	36	.	.	PUNCT
cord-301856-71syce4n	4	1	the	the	DET
cord-301856-71syce4n	4	2	functional	functional	ADJ
cord-301856-71syce4n	4	3	variation	variation	NOUN
cord-301856-71syce4n	4	4	of	of	ADP
cord-301856-71syce4n	4	5	immune	immune	ADJ
cord-301856-71syce4n	4	6	genes	gene	NOUN
cord-301856-71syce4n	4	7	as	as	ADP
cord-301856-71syce4n	4	8	a	a	DET
cord-301856-71syce4n	4	9	result	result	NOUN
cord-301856-71syce4n	4	10	of	of	ADP
cord-301856-71syce4n	4	11	evolution	evolution	NOUN
cord-301856-71syce4n	4	12	is	be	AUX
cord-301856-71syce4n	4	13	relevant	relevant	ADJ
cord-301856-71syce4n	4	14	in	in	ADP
cord-301856-71syce4n	4	15	the	the	DET
cord-301856-71syce4n	4	16	responses	response	NOUN
cord-301856-71syce4n	4	17	against	against	ADP
cord-301856-71syce4n	4	18	infection	infection	NOUN
cord-301856-71syce4n	4	19	,	,	PUNCT
cord-301856-71syce4n	4	20	as	as	ADV
cord-301856-71syce4n	4	21	well	well	ADV
cord-301856-71syce4n	4	22	as	as	ADP
cord-301856-71syce4n	4	23	in	in	ADP
cord-301856-71syce4n	4	24	the	the	DET
cord-301856-71syce4n	4	25	emergence	emergence	NOUN
cord-301856-71syce4n	4	26	of	of	ADP
cord-301856-71syce4n	4	27	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	4	28	and	and	CCONJ
cord-301856-71syce4n	4	29	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	4	30	diseases	disease	NOUN
cord-301856-71syce4n	4	31	observed	observe	VERB
cord-301856-71syce4n	4	32	in	in	ADP
cord-301856-71syce4n	4	33	modern	modern	ADJ
cord-301856-71syce4n	4	34	populations	population	NOUN
cord-301856-71syce4n	4	35	.	.	PUNCT
cord-301856-71syce4n	5	1	understanding	understand	VERB
cord-301856-71syce4n	5	2	how	how	SCONJ
cord-301856-71syce4n	5	3	host	host	NOUN
cord-301856-71syce4n	5	4	–	–	PUNCT
cord-301856-71syce4n	5	5	pathogen	pathogen	PROPN
cord-301856-71syce4n	5	6	interactions	interaction	NOUN
cord-301856-71syce4n	5	7	have	have	AUX
cord-301856-71syce4n	5	8	influenced	influence	VERB
cord-301856-71syce4n	5	9	the	the	DET
cord-301856-71syce4n	5	10	human	human	ADJ
cord-301856-71syce4n	5	11	immune	immune	ADJ
cord-301856-71syce4n	5	12	system	system	NOUN
cord-301856-71syce4n	5	13	from	from	ADP
cord-301856-71syce4n	5	14	an	an	DET
cord-301856-71syce4n	5	15	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	5	16	perspective	perspective	NOUN
cord-301856-71syce4n	5	17	might	might	AUX
cord-301856-71syce4n	5	18	contribute	contribute	VERB
cord-301856-71syce4n	5	19	to	to	ADP
cord-301856-71syce4n	5	20	unveiling	unveil	VERB
cord-301856-71syce4n	5	21	the	the	DET
cord-301856-71syce4n	5	22	causes	cause	NOUN
cord-301856-71syce4n	5	23	behind	behind	ADP
cord-301856-71syce4n	5	24	different	different	ADJ
cord-301856-71syce4n	5	25	immune	immune	ADJ
cord-301856-71syce4n	5	26	-	-	PUNCT
cord-301856-71syce4n	5	27	mediated	mediate	VERB
cord-301856-71syce4n	5	28	disorders	disorder	NOUN
cord-301856-71syce4n	5	29	and	and	CCONJ
cord-301856-71syce4n	5	30	promote	promote	VERB
cord-301856-71syce4n	5	31	the	the	DET
cord-301856-71syce4n	5	32	development	development	NOUN
cord-301856-71syce4n	5	33	of	of	ADP
cord-301856-71syce4n	5	34	new	new	ADJ
cord-301856-71syce4n	5	35	strategies	strategy	NOUN
cord-301856-71syce4n	5	36	to	to	PART
cord-301856-71syce4n	5	37	detect	detect	VERB
cord-301856-71syce4n	5	38	and	and	CCONJ
cord-301856-71syce4n	5	39	control	control	VERB
cord-301856-71syce4n	5	40	such	such	ADJ
cord-301856-71syce4n	5	41	diseases	disease	NOUN
cord-301856-71syce4n	5	42	.	.	PUNCT
cord-301856-71syce4n	6	1	the	the	DET
cord-301856-71syce4n	6	2	evolution	evolution	NOUN
cord-301856-71syce4n	6	3	of	of	ADP
cord-301856-71syce4n	6	4	mankind	mankind	NOUN
cord-301856-71syce4n	6	5	has	have	AUX
cord-301856-71syce4n	6	6	constantly	constantly	ADV
cord-301856-71syce4n	6	7	been	be	AUX
cord-301856-71syce4n	6	8	influenced	influence	VERB
cord-301856-71syce4n	6	9	by	by	ADP
cord-301856-71syce4n	6	10	the	the	DET
cord-301856-71syce4n	6	11	pathogens	pathogen	NOUN
cord-301856-71syce4n	6	12	encountered	encounter	VERB
cord-301856-71syce4n	6	13	.	.	PUNCT
cord-301856-71syce4n	7	1	the	the	DET
cord-301856-71syce4n	7	2	various	various	ADJ
cord-301856-71syce4n	7	3	populations	population	NOUN
cord-301856-71syce4n	7	4	of	of	ADP
cord-301856-71syce4n	7	5	modern	modern	ADJ
cord-301856-71syce4n	7	6	humans	human	NOUN
cord-301856-71syce4n	7	7	that	that	PRON
cord-301856-71syce4n	7	8	ventured	venture	VERB
cord-301856-71syce4n	7	9	out	out	ADP
cord-301856-71syce4n	7	10	of	of	ADP
cord-301856-71syce4n	7	11	africa	africa	PROPN
cord-301856-71syce4n	7	12	adapted	adapt	VERB
cord-301856-71syce4n	7	13	to	to	ADP
cord-301856-71syce4n	7	14	different	different	ADJ
cord-301856-71syce4n	7	15	environments	environment	NOUN
cord-301856-71syce4n	7	16	and	and	CCONJ
cord-301856-71syce4n	7	17	faced	face	VERB
cord-301856-71syce4n	7	18	a	a	DET
cord-301856-71syce4n	7	19	large	large	ADJ
cord-301856-71syce4n	7	20	variety	variety	NOUN
cord-301856-71syce4n	7	21	of	of	ADP
cord-301856-71syce4n	7	22	infectious	infectious	ADJ
cord-301856-71syce4n	7	23	agents	agent	NOUN
cord-301856-71syce4n	7	24	,	,	PUNCT
cord-301856-71syce4n	7	25	resulting	result	VERB
cord-301856-71syce4n	7	26	in	in	ADP
cord-301856-71syce4n	7	27	local	local	ADJ
cord-301856-71syce4n	7	28	adaptations	adaptation	NOUN
cord-301856-71syce4n	7	29	of	of	ADP
cord-301856-71syce4n	7	30	the	the	DET
cord-301856-71syce4n	7	31	immune	immune	ADJ
cord-301856-71syce4n	7	32	system	system	NOUN
cord-301856-71syce4n	7	33	for	for	ADP
cord-301856-71syce4n	7	34	these	these	DET
cord-301856-71syce4n	7	35	populations	population	NOUN
cord-301856-71syce4n	7	36	.	.	PUNCT
cord-301856-71syce4n	8	1	the	the	DET
cord-301856-71syce4n	8	2	functional	functional	ADJ
cord-301856-71syce4n	8	3	variation	variation	NOUN
cord-301856-71syce4n	8	4	of	of	ADP
cord-301856-71syce4n	8	5	immune	immune	ADJ
cord-301856-71syce4n	8	6	genes	gene	NOUN
cord-301856-71syce4n	8	7	as	as	ADP
cord-301856-71syce4n	8	8	a	a	DET
cord-301856-71syce4n	8	9	result	result	NOUN
cord-301856-71syce4n	8	10	of	of	ADP
cord-301856-71syce4n	8	11	evolution	evolution	NOUN
cord-301856-71syce4n	8	12	is	be	AUX
cord-301856-71syce4n	8	13	relevant	relevant	ADJ
cord-301856-71syce4n	8	14	in	in	ADP
cord-301856-71syce4n	8	15	the	the	DET
cord-301856-71syce4n	8	16	responses	response	NOUN
cord-301856-71syce4n	8	17	against	against	ADP
cord-301856-71syce4n	8	18	infection	infection	NOUN
cord-301856-71syce4n	8	19	,	,	PUNCT
cord-301856-71syce4n	8	20	as	as	ADV
cord-301856-71syce4n	8	21	well	well	ADV
cord-301856-71syce4n	8	22	as	as	ADP
cord-301856-71syce4n	8	23	in	in	ADP
cord-301856-71syce4n	8	24	the	the	DET
cord-301856-71syce4n	8	25	emergence	emergence	NOUN
cord-301856-71syce4n	8	26	of	of	ADP
cord-301856-71syce4n	8	27	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	8	28	and	and	CCONJ
cord-301856-71syce4n	8	29	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	8	30	diseases	disease	NOUN
cord-301856-71syce4n	8	31	observed	observe	VERB
cord-301856-71syce4n	8	32	in	in	ADP
cord-301856-71syce4n	8	33	modern	modern	ADJ
cord-301856-71syce4n	8	34	populations	population	NOUN
cord-301856-71syce4n	8	35	.	.	PUNCT
cord-301856-71syce4n	9	1	understanding	understand	VERB
cord-301856-71syce4n	9	2	how	how	SCONJ
cord-301856-71syce4n	9	3	host	host	NOUN
cord-301856-71syce4n	9	4	-	-	PUNCT
cord-301856-71syce4n	9	5	pathogen	pathogen	PROPN
cord-301856-71syce4n	9	6	interactions	interaction	NOUN
cord-301856-71syce4n	9	7	have	have	AUX
cord-301856-71syce4n	9	8	influenced	influence	VERB
cord-301856-71syce4n	9	9	the	the	DET
cord-301856-71syce4n	9	10	human	human	ADJ
cord-301856-71syce4n	9	11	immune	immune	ADJ
cord-301856-71syce4n	9	12	system	system	NOUN
cord-301856-71syce4n	9	13	from	from	ADP
cord-301856-71syce4n	9	14	an	an	DET
cord-301856-71syce4n	9	15	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	9	16	perspective	perspective	NOUN
cord-301856-71syce4n	9	17	might	might	AUX
cord-301856-71syce4n	9	18	contribute	contribute	VERB
cord-301856-71syce4n	9	19	to	to	ADP
cord-301856-71syce4n	9	20	unveiling	unveil	VERB
cord-301856-71syce4n	9	21	the	the	DET
cord-301856-71syce4n	9	22	causes	cause	NOUN
cord-301856-71syce4n	9	23	behind	behind	ADP
cord-301856-71syce4n	9	24	different	different	ADJ
cord-301856-71syce4n	9	25	immune	immune	ADJ
cord-301856-71syce4n	9	26	-	-	PUNCT
cord-301856-71syce4n	9	27	mediated	mediate	VERB
cord-301856-71syce4n	9	28	disorders	disorder	NOUN
cord-301856-71syce4n	9	29	and	and	CCONJ
cord-301856-71syce4n	9	30	promote	promote	VERB
cord-301856-71syce4n	9	31	the	the	DET
cord-301856-71syce4n	9	32	development	development	NOUN
cord-301856-71syce4n	9	33	of	of	ADP
cord-301856-71syce4n	9	34	new	new	ADJ
cord-301856-71syce4n	9	35	strategies	strategy	NOUN
cord-301856-71syce4n	9	36	to	to	PART
cord-301856-71syce4n	9	37	detect	detect	VERB
cord-301856-71syce4n	9	38	and	and	CCONJ
cord-301856-71syce4n	9	39	control	control	VERB
cord-301856-71syce4n	9	40	such	such	ADJ
cord-301856-71syce4n	9	41	diseases	disease	NOUN
cord-301856-71syce4n	9	42	.	.	PUNCT
cord-301856-71syce4n	10	1	infectious	infectious	ADJ
cord-301856-71syce4n	10	2	diseases	disease	NOUN
cord-301856-71syce4n	10	3	are	be	AUX
cord-301856-71syce4n	10	4	arguably	arguably	ADV
cord-301856-71syce4n	10	5	the	the	DET
cord-301856-71syce4n	10	6	main	main	ADJ
cord-301856-71syce4n	10	7	source	source	NOUN
cord-301856-71syce4n	10	8	of	of	ADP
cord-301856-71syce4n	10	9	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	10	10	pressure	pressure	NOUN
cord-301856-71syce4n	10	11	that	that	SCONJ
cord-301856-71syce4n	10	12	humanity	humanity	NOUN
cord-301856-71syce4n	10	13	has	have	AUX
cord-301856-71syce4n	10	14	ever	ever	ADV
cord-301856-71syce4n	10	15	confronted	confront	VERB
cord-301856-71syce4n	10	16	.	.	PUNCT
cord-301856-71syce4n	11	1	the	the	DET
cord-301856-71syce4n	11	2	dispersion	dispersion	NOUN
cord-301856-71syce4n	11	3	of	of	ADP
cord-301856-71syce4n	11	4	different	different	ADJ
cord-301856-71syce4n	11	5	human	human	ADJ
cord-301856-71syce4n	11	6	communities	community	NOUN
cord-301856-71syce4n	11	7	around	around	ADP
cord-301856-71syce4n	11	8	the	the	DET
cord-301856-71syce4n	11	9	globe	globe	NOUN
cord-301856-71syce4n	11	10	has	have	AUX
cord-301856-71syce4n	11	11	exposed	expose	VERB
cord-301856-71syce4n	11	12	each	each	DET
cord-301856-71syce4n	11	13	population	population	NOUN
cord-301856-71syce4n	11	14	to	to	ADP
cord-301856-71syce4n	11	15	different	different	ADJ
cord-301856-71syce4n	11	16	infectious	infectious	ADJ
cord-301856-71syce4n	11	17	agents	agent	NOUN
cord-301856-71syce4n	11	18	,	,	PUNCT
cord-301856-71syce4n	11	19	exerting	exert	VERB
cord-301856-71syce4n	11	20	a	a	DET
cord-301856-71syce4n	11	21	selective	selective	ADJ
cord-301856-71syce4n	11	22	pressure	pressure	NOUN
cord-301856-71syce4n	11	23	(	(	PUNCT
cord-301856-71syce4n	11	24	see	see	VERB
cord-301856-71syce4n	11	25	glossary	glossary	ADJ
cord-301856-71syce4n	11	26	)	)	PUNCT
cord-301856-71syce4n	11	27	on	on	ADP
cord-301856-71syce4n	11	28	them	they	PRON
cord-301856-71syce4n	11	29	;	;	PUNCT
cord-301856-71syce4n	11	30	thus	thus	ADV
cord-301856-71syce4n	11	31	,	,	PUNCT
cord-301856-71syce4n	11	32	adaptation	adaptation	NOUN
cord-301856-71syce4n	11	33	to	to	ADP
cord-301856-71syce4n	11	34	the	the	DET
cord-301856-71syce4n	11	35	new	new	ADJ
cord-301856-71syce4n	11	36	environment	environment	NOUN
cord-301856-71syce4n	11	37	has	have	AUX
cord-301856-71syce4n	11	38	favored	favor	VERB
cord-301856-71syce4n	11	39	the	the	DET
cord-301856-71syce4n	11	40	selection	selection	NOUN
cord-301856-71syce4n	11	41	of	of	ADP
cord-301856-71syce4n	11	42	the	the	DET
cord-301856-71syce4n	11	43	most	most	ADV
cord-301856-71syce4n	11	44	beneficial	beneficial	ADJ
cord-301856-71syce4n	11	45	genetic	genetic	ADJ
cord-301856-71syce4n	11	46	variants	variant	NOUN
cord-301856-71syce4n	11	47	for	for	ADP
cord-301856-71syce4n	11	48	the	the	DET
cord-301856-71syce4n	11	49	host	host	NOUN
cord-301856-71syce4n	11	50	.	.	PUNCT
cord-301856-71syce4n	12	1	as	as	ADP
cord-301856-71syce4n	12	2	a	a	DET
cord-301856-71syce4n	12	3	result	result	NOUN
cord-301856-71syce4n	12	4	,	,	PUNCT
cord-301856-71syce4n	12	5	infectious	infectious	ADJ
cord-301856-71syce4n	12	6	agents	agent	NOUN
cord-301856-71syce4n	12	7	have	have	AUX
cord-301856-71syce4n	12	8	caused	cause	VERB
cord-301856-71syce4n	12	9	the	the	DET
cord-301856-71syce4n	12	10	expansion	expansion	NOUN
cord-301856-71syce4n	12	11	of	of	ADP
cord-301856-71syce4n	12	12	alleles	allele	NOUN
cord-301856-71syce4n	12	13	behind	behind	ADP
cord-301856-71syce4n	12	14	the	the	DET
cord-301856-71syce4n	12	15	induction	induction	NOUN
cord-301856-71syce4n	12	16	of	of	ADP
cord-301856-71syce4n	12	17	either	either	CCONJ
cord-301856-71syce4n	12	18	protection	protection	NOUN
cord-301856-71syce4n	12	19	or	or	CCONJ
cord-301856-71syce4n	12	20	tolerance	tolerance	NOUN
cord-301856-71syce4n	12	21	to	to	ADP
cord-301856-71syce4n	12	22	these	these	DET
cord-301856-71syce4n	12	23	diseases	disease	NOUN
cord-301856-71syce4n	12	24	;	;	PUNCT
cord-301856-71syce4n	12	25	heritable	heritable	ADJ
cord-301856-71syce4n	12	26	variations	variation	NOUN
cord-301856-71syce4n	12	27	,	,	PUNCT
cord-301856-71syce4n	12	28	that	that	PRON
cord-301856-71syce4n	12	29	increased	increase	VERB
cord-301856-71syce4n	12	30	the	the	DET
cord-301856-71syce4n	12	31	survival	survival	NOUN
cord-301856-71syce4n	12	32	to	to	ADP
cord-301856-71syce4n	12	33	deadly	deadly	ADJ
cord-301856-71syce4n	12	34	infectious	infectious	ADJ
cord-301856-71syce4n	12	35	agents	agent	NOUN
cord-301856-71syce4n	12	36	,	,	PUNCT
cord-301856-71syce4n	12	37	may	may	AUX
cord-301856-71syce4n	12	38	have	have	AUX
cord-301856-71syce4n	12	39	been	be	AUX
cord-301856-71syce4n	12	40	naturally	naturally	ADV
cord-301856-71syce4n	12	41	selected	select	VERB
cord-301856-71syce4n	12	42	before	before	SCONJ
cord-301856-71syce4n	12	43	the	the	DET
cord-301856-71syce4n	12	44	hosts	host	NOUN
cord-301856-71syce4n	12	45	had	have	VERB
cord-301856-71syce4n	12	46	the	the	DET
cord-301856-71syce4n	12	47	opportunity	opportunity	NOUN
cord-301856-71syce4n	12	48	to	to	PART
cord-301856-71syce4n	12	49	reproduce	reproduce	VERB
cord-301856-71syce4n	12	50	[	[	SYM
cord-301856-71syce4n	12	51	1	1	NUM
cord-301856-71syce4n	12	52	]	]	PUNCT
cord-301856-71syce4n	12	53	.	.	PUNCT
cord-301856-71syce4n	13	1	natural	natural	ADJ
cord-301856-71syce4n	13	2	selection	selection	NOUN
cord-301856-71syce4n	13	3	driven	drive	VERB
cord-301856-71syce4n	13	4	by	by	ADP
cord-301856-71syce4n	13	5	pathogens	pathogen	NOUN
cord-301856-71syce4n	13	6	is	be	AUX
cord-301856-71syce4n	13	7	probably	probably	ADV
cord-301856-71syce4n	13	8	more	more	ADV
cord-301856-71syce4n	13	9	remarkable	remarkable	ADJ
cord-301856-71syce4n	13	10	for	for	ADP
cord-301856-71syce4n	13	11	those	those	DET
cord-301856-71syce4n	13	12	infectious	infectious	ADJ
cord-301856-71syce4n	13	13	agents	agent	NOUN
cord-301856-71syce4n	13	14	that	that	PRON
cord-301856-71syce4n	13	15	have	have	AUX
cord-301856-71syce4n	13	16	been	be	AUX
cord-301856-71syce4n	13	17	among	among	ADP
cord-301856-71syce4n	13	18	us	we	PRON
cord-301856-71syce4n	13	19	for	for	ADP
cord-301856-71syce4n	13	20	a	a	DET
cord-301856-71syce4n	13	21	longer	long	ADJ
cord-301856-71syce4n	13	22	time	time	NOUN
cord-301856-71syce4n	13	23	,	,	PUNCT
cord-301856-71syce4n	13	24	namely	namely	ADV
cord-301856-71syce4n	13	25	the	the	DET
cord-301856-71syce4n	13	26	causative	causative	ADJ
cord-301856-71syce4n	13	27	agents	agent	NOUN
cord-301856-71syce4n	13	28	of	of	ADP
cord-301856-71syce4n	13	29	well	well	ADV
cord-301856-71syce4n	13	30	-	-	PUNCT
cord-301856-71syce4n	13	31	known	know	VERB
cord-301856-71syce4n	13	32	diseases	disease	NOUN
cord-301856-71syce4n	13	33	such	such	ADJ
cord-301856-71syce4n	13	34	as	as	ADP
cord-301856-71syce4n	13	35	leprosy	leprosy	NOUN
cord-301856-71syce4n	13	36	,	,	PUNCT
cord-301856-71syce4n	13	37	smallpox	smallpox	NOUN
cord-301856-71syce4n	13	38	,	,	PUNCT
cord-301856-71syce4n	13	39	malaria	malaria	NOUN
cord-301856-71syce4n	13	40	,	,	PUNCT
cord-301856-71syce4n	13	41	or	or	CCONJ
cord-301856-71syce4n	13	42	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	13	43	.	.	PUNCT
cord-301856-71syce4n	14	1	the	the	DET
cord-301856-71syce4n	14	2	genetic	genetic	ADJ
cord-301856-71syce4n	14	3	imprint	imprint	NOUN
cord-301856-71syce4n	14	4	of	of	ADP
cord-301856-71syce4n	14	5	pathogen	pathogen	PROPN
cord-301856-71syce4n	14	6	-	-	PUNCT
cord-301856-71syce4n	14	7	driven	drive	VERB
cord-301856-71syce4n	14	8	selection	selection	NOUN
cord-301856-71syce4n	14	9	depends	depend	VERB
cord-301856-71syce4n	14	10	on	on	ADP
cord-301856-71syce4n	14	11	the	the	DET
cord-301856-71syce4n	14	12	length	length	NOUN
cord-301856-71syce4n	14	13	and	and	CCONJ
cord-301856-71syce4n	14	14	the	the	DET
cord-301856-71syce4n	14	15	virulence	virulence	NOUN
cord-301856-71syce4n	14	16	of	of	ADP
cord-301856-71syce4n	14	17	the	the	DET
cord-301856-71syce4n	14	18	infections	infection	NOUN
cord-301856-71syce4n	14	19	and	and	CCONJ
cord-301856-71syce4n	14	20	also	also	ADV
cord-301856-71syce4n	14	21	the	the	DET
cord-301856-71syce4n	14	22	geographical	geographical	ADJ
cord-301856-71syce4n	14	23	distribution	distribution	NOUN
cord-301856-71syce4n	14	24	.	.	PUNCT
cord-301856-71syce4n	15	1	the	the	DET
cord-301856-71syce4n	15	2	human	human	ADJ
cord-301856-71syce4n	15	3	genome	genome	NOUN
cord-301856-71syce4n	15	4	presents	present	VERB
cord-301856-71syce4n	15	5	more	more	ADJ
cord-301856-71syce4n	15	6	than	than	ADP
cord-301856-71syce4n	15	7	5000	5000	NUM
cord-301856-71syce4n	15	8	genetic	genetic	ADJ
cord-301856-71syce4n	15	9	loci	loci	NOUN
cord-301856-71syce4n	15	10	with	with	ADP
cord-301856-71syce4n	15	11	traces	trace	NOUN
cord-301856-71syce4n	15	12	of	of	ADP
cord-301856-71syce4n	15	13	selective	selective	ADJ
cord-301856-71syce4n	15	14	pressure	pressure	NOUN
cord-301856-71syce4n	15	15	[	[	X
cord-301856-71syce4n	15	16	2	2	NUM
cord-301856-71syce4n	15	17	]	]	PUNCT
cord-301856-71syce4n	15	18	.	.	PUNCT
cord-301856-71syce4n	16	1	this	this	DET
cord-301856-71syce4n	16	2	group	group	NOUN
cord-301856-71syce4n	16	3	includes	include	VERB
cord-301856-71syce4n	16	4	more	more	ADJ
cord-301856-71syce4n	16	5	than	than	ADP
cord-301856-71syce4n	16	6	300	300	NUM
cord-301856-71syce4n	16	7	immune	immune	ADJ
cord-301856-71syce4n	16	8	-	-	PUNCT
cord-301856-71syce4n	16	9	related	relate	VERB
cord-301856-71syce4n	16	10	genes	gene	NOUN
cord-301856-71syce4n	16	11	with	with	ADP
cord-301856-71syce4n	16	12	functional	functional	ADJ
cord-301856-71syce4n	16	13	variations	variation	NOUN
cord-301856-71syce4n	16	14	between	between	ADP
cord-301856-71syce4n	16	15	populations	population	NOUN
cord-301856-71syce4n	16	16	,	,	PUNCT
cord-301856-71syce4n	16	17	which	which	PRON
cord-301856-71syce4n	16	18	are	be	AUX
cord-301856-71syce4n	16	19	probably	probably	ADV
cord-301856-71syce4n	16	20	behind	behind	ADP
cord-301856-71syce4n	16	21	the	the	DET
cord-301856-71syce4n	16	22	variability	variability	NOUN
cord-301856-71syce4n	16	23	of	of	ADP
cord-301856-71syce4n	16	24	responses	response	NOUN
cord-301856-71syce4n	16	25	to	to	ADP
cord-301856-71syce4n	16	26	immune	immune	NOUN
cord-301856-71syce4n	16	27	-	-	PUNCT
cord-301856-71syce4n	16	28	related	relate	VERB
cord-301856-71syce4n	16	29	diseases	disease	NOUN
cord-301856-71syce4n	16	30	reported	report	VERB
cord-301856-71syce4n	16	31	nowadays	nowadays	ADV
cord-301856-71syce4n	16	32	[	[	X
cord-301856-71syce4n	16	33	3	3	NUM
cord-301856-71syce4n	16	34	,	,	PUNCT
cord-301856-71syce4n	16	35	4	4	NUM
cord-301856-71syce4n	16	36	]	]	PUNCT
cord-301856-71syce4n	16	37	.	.	PUNCT
cord-301856-71syce4n	17	1	besides	besides	SCONJ
cord-301856-71syce4n	17	2	natural	natural	ADJ
cord-301856-71syce4n	17	3	selection	selection	NOUN
cord-301856-71syce4n	17	4	,	,	PUNCT
cord-301856-71syce4n	17	5	other	other	ADJ
cord-301856-71syce4n	17	6	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	17	7	mechanisms	mechanism	NOUN
cord-301856-71syce4n	17	8	,	,	PUNCT
cord-301856-71syce4n	17	9	such	such	ADJ
cord-301856-71syce4n	17	10	as	as	ADP
cord-301856-71syce4n	17	11	genetic	genetic	ADJ
cord-301856-71syce4n	17	12	drift	drift	NOUN
cord-301856-71syce4n	17	13	,	,	PUNCT
cord-301856-71syce4n	17	14	greatly	greatly	ADV
cord-301856-71syce4n	17	15	influence	influence	VERB
cord-301856-71syce4n	17	16	the	the	DET
cord-301856-71syce4n	17	17	frequencies	frequency	NOUN
cord-301856-71syce4n	17	18	of	of	ADP
cord-301856-71syce4n	17	19	the	the	DET
cord-301856-71syce4n	17	20	genetic	genetic	ADJ
cord-301856-71syce4n	17	21	variants	variant	NOUN
cord-301856-71syce4n	17	22	found	find	VERB
cord-301856-71syce4n	17	23	within	within	ADP
cord-301856-71syce4n	17	24	diverse	diverse	ADJ
cord-301856-71syce4n	17	25	populations	population	NOUN
cord-301856-71syce4n	17	26	throughout	throughout	ADP
cord-301856-71syce4n	17	27	the	the	DET
cord-301856-71syce4n	17	28	world	world	NOUN
cord-301856-71syce4n	17	29	[	[	PUNCT
cord-301856-71syce4n	17	30	5	5	NUM
cord-301856-71syce4n	17	31	]	]	X
cord-301856-71syce4n	17	32	(	(	PUNCT
cord-301856-71syce4n	17	33	box	box	NOUN
cord-301856-71syce4n	17	34	1	1	NUM
cord-301856-71syce4n	17	35	and	and	CCONJ
cord-301856-71syce4n	17	36	figure	figure	VERB
cord-301856-71syce4n	17	37	1	1	NUM
cord-301856-71syce4n	17	38	)	)	PUNCT
cord-301856-71syce4n	17	39	.	.	PUNCT
cord-301856-71syce4n	18	1	with	with	ADP
cord-301856-71syce4n	18	2	the	the	DET
cord-301856-71syce4n	18	3	burst	burst	NOUN
cord-301856-71syce4n	18	4	of	of	ADP
cord-301856-71syce4n	18	5	next	next	ADJ
cord-301856-71syce4n	18	6	-	-	PUNCT
cord-301856-71syce4n	18	7	generation	generation	NOUN
cord-301856-71syce4n	18	8	sequencing	sequencing	NOUN
cord-301856-71syce4n	18	9	and	and	CCONJ
cord-301856-71syce4n	18	10	the	the	DET
cord-301856-71syce4n	18	11	development	development	NOUN
cord-301856-71syce4n	18	12	of	of	ADP
cord-301856-71syce4n	18	13	cutting	cut	VERB
cord-301856-71syce4n	18	14	-	-	PUNCT
cord-301856-71syce4n	18	15	edge	edge	NOUN
cord-301856-71syce4n	18	16	technologies	technology	NOUN
cord-301856-71syce4n	18	17	such	such	ADJ
cord-301856-71syce4n	18	18	as	as	ADP
cord-301856-71syce4n	18	19	transcriptomics	transcriptomic	NOUN
cord-301856-71syce4n	18	20	,	,	PUNCT
cord-301856-71syce4n	18	21	proteomics	proteomic	NOUN
cord-301856-71syce4n	18	22	,	,	PUNCT
cord-301856-71syce4n	18	23	and	and	CCONJ
cord-301856-71syce4n	18	24	systems	system	NOUN
cord-301856-71syce4n	18	25	biology	biology	NOUN
cord-301856-71syce4n	18	26	,	,	PUNCT
cord-301856-71syce4n	18	27	we	we	PRON
cord-301856-71syce4n	18	28	are	be	AUX
cord-301856-71syce4n	18	29	starting	start	VERB
cord-301856-71syce4n	18	30	to	to	PART
cord-301856-71syce4n	18	31	witness	witness	VERB
cord-301856-71syce4n	18	32	the	the	DET
cord-301856-71syce4n	18	33	great	great	ADJ
cord-301856-71syce4n	18	34	impact	impact	NOUN
cord-301856-71syce4n	18	35	of	of	ADP
cord-301856-71syce4n	18	36	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	18	37	processes	process	NOUN
cord-301856-71syce4n	18	38	on	on	ADP
cord-301856-71syce4n	18	39	human	human	ADJ
cord-301856-71syce4n	18	40	immunity	immunity	NOUN
cord-301856-71syce4n	18	41	and	and	CCONJ
cord-301856-71syce4n	18	42	how	how	SCONJ
cord-301856-71syce4n	18	43	the	the	DET
cord-301856-71syce4n	18	44	interactions	interaction	NOUN
cord-301856-71syce4n	18	45	between	between	ADP
cord-301856-71syce4n	18	46	microorganisms	microorganism	NOUN
cord-301856-71syce4n	18	47	and	and	CCONJ
cord-301856-71syce4n	18	48	humans	human	NOUN
cord-301856-71syce4n	18	49	that	that	PRON
cord-301856-71syce4n	18	50	took	take	VERB
cord-301856-71syce4n	18	51	place	place	NOUN
cord-301856-71syce4n	18	52	millennia	millennium	NOUN
cord-301856-71syce4n	18	53	ago	ago	ADV
cord-301856-71syce4n	18	54	might	might	AUX
cord-301856-71syce4n	18	55	play	play	VERB
cord-301856-71syce4n	18	56	a	a	DET
cord-301856-71syce4n	18	57	fundamental	fundamental	ADJ
cord-301856-71syce4n	18	58	role	role	NOUN
cord-301856-71syce4n	18	59	not	not	PART
cord-301856-71syce4n	18	60	only	only	ADV
cord-301856-71syce4n	18	61	in	in	ADP
cord-301856-71syce4n	18	62	the	the	DET
cord-301856-71syce4n	18	63	response	response	NOUN
cord-301856-71syce4n	18	64	against	against	ADP
cord-301856-71syce4n	18	65	modern	modern	ADJ
cord-301856-71syce4n	18	66	pathogenic	pathogenic	ADJ
cord-301856-71syce4n	18	67	threats	threat	NOUN
cord-301856-71syce4n	18	68	,	,	PUNCT
cord-301856-71syce4n	18	69	but	but	CCONJ
cord-301856-71syce4n	18	70	also	also	ADV
cord-301856-71syce4n	18	71	in	in	ADP
cord-301856-71syce4n	18	72	the	the	DET
cord-301856-71syce4n	18	73	emergence	emergence	NOUN
cord-301856-71syce4n	18	74	of	of	ADP
cord-301856-71syce4n	18	75	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	18	76	and	and	CCONJ
cord-301856-71syce4n	18	77	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	18	78	diseases	disease	NOUN
cord-301856-71syce4n	18	79	observed	observe	VERB
cord-301856-71syce4n	18	80	in	in	ADP
cord-301856-71syce4n	18	81	modern	modern	ADJ
cord-301856-71syce4n	18	82	populations	population	NOUN
cord-301856-71syce4n	18	83	worldwide	worldwide	ADV
cord-301856-71syce4n	18	84	.	.	PUNCT
cord-301856-71syce4n	19	1	in	in	ADP
cord-301856-71syce4n	19	2	this	this	DET
cord-301856-71syce4n	19	3	review	review	NOUN
cord-301856-71syce4n	19	4	we	we	PRON
cord-301856-71syce4n	19	5	offer	offer	VERB
cord-301856-71syce4n	19	6	a	a	DET
cord-301856-71syce4n	19	7	novel	novel	ADJ
cord-301856-71syce4n	19	8	perspective	perspective	NOUN
cord-301856-71syce4n	19	9	on	on	ADP
cord-301856-71syce4n	19	10	the	the	DET
cord-301856-71syce4n	19	11	role	role	NOUN
cord-301856-71syce4n	19	12	of	of	ADP
cord-301856-71syce4n	19	13	infectious	infectious	ADJ
cord-301856-71syce4n	19	14	diseases	disease	NOUN
cord-301856-71syce4n	19	15	as	as	ADP
cord-301856-71syce4n	19	16	agents	agent	NOUN
cord-301856-71syce4n	19	17	of	of	ADP
cord-301856-71syce4n	19	18	natural	natural	ADJ
cord-301856-71syce4n	19	19	selection	selection	NOUN
cord-301856-71syce4n	19	20	and	and	CCONJ
cord-301856-71syce4n	19	21	as	as	ADP
cord-301856-71syce4n	19	22	forces	force	NOUN
cord-301856-71syce4n	19	23	behind	behind	ADP
cord-301856-71syce4n	19	24	the	the	DET
cord-301856-71syce4n	19	25	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	19	26	pressure	pressure	NOUN
cord-301856-71syce4n	19	27	encountered	encounter	VERB
cord-301856-71syce4n	19	28	by	by	ADP
cord-301856-71syce4n	19	29	human	human	ADJ
cord-301856-71syce4n	19	30	ancestors	ancestor	NOUN
cord-301856-71syce4n	19	31	and	and	CCONJ
cord-301856-71syce4n	19	32	modern	modern	ADJ
cord-301856-71syce4n	19	33	humans	human	NOUN
cord-301856-71syce4n	19	34	in	in	ADP
cord-301856-71syce4n	19	35	their	their	PRON
cord-301856-71syce4n	19	36	migrations	migration	NOUN
cord-301856-71syce4n	19	37	around	around	ADP
cord-301856-71syce4n	19	38	the	the	DET
cord-301856-71syce4n	19	39	globe	globe	NOUN
cord-301856-71syce4n	19	40	.	.	PUNCT
cord-301856-71syce4n	20	1	specific	specific	ADJ
cord-301856-71syce4n	20	2	genetic	genetic	ADJ
cord-301856-71syce4n	20	3	variants	variant	NOUN
cord-301856-71syce4n	20	4	selected	select	VERB
cord-301856-71syce4n	20	5	throughout	throughout	ADP
cord-301856-71syce4n	20	6	different	different	ADJ
cord-301856-71syce4n	20	7	periods	period	NOUN
cord-301856-71syce4n	20	8	of	of	ADP
cord-301856-71syce4n	20	9	human	human	ADJ
cord-301856-71syce4n	20	10	history	history	NOUN
cord-301856-71syce4n	20	11	may	may	AUX
cord-301856-71syce4n	20	12	have	have	AUX
cord-301856-71syce4n	20	13	influenced	influence	VERB
cord-301856-71syce4n	20	14	immune	immune	ADJ
cord-301856-71syce4n	20	15	responses	response	NOUN
cord-301856-71syce4n	20	16	of	of	ADP
cord-301856-71syce4n	20	17	present	present	ADJ
cord-301856-71syce4n	20	18	-	-	PUNCT
cord-301856-71syce4n	20	19	day	day	NOUN
cord-301856-71syce4n	20	20	populations	population	NOUN
cord-301856-71syce4n	20	21	against	against	ADP
cord-301856-71syce4n	20	22	pathogenic	pathogenic	ADJ
cord-301856-71syce4n	20	23	microorganisms	microorganism	NOUN
cord-301856-71syce4n	20	24	and	and	CCONJ
cord-301856-71syce4n	20	25	may	may	AUX
cord-301856-71syce4n	20	26	have	have	AUX
cord-301856-71syce4n	20	27	played	play	VERB
cord-301856-71syce4n	20	28	a	a	DET
cord-301856-71syce4n	20	29	role	role	NOUN
cord-301856-71syce4n	20	30	in	in	ADP
cord-301856-71syce4n	20	31	the	the	DET
cord-301856-71syce4n	20	32	development	development	NOUN
cord-301856-71syce4n	20	33	of	of	ADP
cord-301856-71syce4n	20	34	certain	certain	ADJ
cord-301856-71syce4n	20	35	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	20	36	and	and	CCONJ
cord-301856-71syce4n	20	37	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	20	38	diseases	disease	NOUN
cord-301856-71syce4n	20	39	.	.	PUNCT
cord-301856-71syce4n	21	1	the	the	DET
cord-301856-71syce4n	21	2	majority	majority	NOUN
cord-301856-71syce4n	21	3	of	of	ADP
cord-301856-71syce4n	21	4	experts	expert	NOUN
cord-301856-71syce4n	21	5	agree	agree	VERB
cord-301856-71syce4n	21	6	that	that	SCONJ
cord-301856-71syce4n	21	7	africa	africa	PROPN
cord-301856-71syce4n	21	8	is	be	AUX
cord-301856-71syce4n	21	9	where	where	SCONJ
cord-301856-71syce4n	21	10	our	our	PRON
cord-301856-71syce4n	21	11	species	specie	NOUN
cord-301856-71syce4n	21	12	originated	originate	VERB
cord-301856-71syce4n	21	13	.	.	PUNCT
cord-301856-71syce4n	22	1	genetic	genetic	ADJ
cord-301856-71syce4n	22	2	studies	study	NOUN
cord-301856-71syce4n	22	3	conducted	conduct	VERB
cord-301856-71syce4n	22	4	in	in	ADP
cord-301856-71syce4n	22	5	diverse	diverse	ADJ
cord-301856-71syce4n	22	6	contemporary	contemporary	ADJ
cord-301856-71syce4n	22	7	populations	population	NOUN
cord-301856-71syce4n	22	8	suggest	suggest	VERB
cord-301856-71syce4n	22	9	connections	connection	NOUN
cord-301856-71syce4n	22	10	with	with	ADP
cord-301856-71syce4n	22	11	ancestors	ancestor	NOUN
cord-301856-71syce4n	22	12	that	that	PRON
cord-301856-71syce4n	22	13	lived	live	VERB
cord-301856-71syce4n	22	14	on	on	ADP
cord-301856-71syce4n	22	15	the	the	DET
cord-301856-71syce4n	22	16	continent	continent	NOUN
cord-301856-71syce4n	22	17	up	up	ADP
cord-301856-71syce4n	22	18	to	to	PART
cord-301856-71syce4n	22	19	350	350	NUM
cord-301856-71syce4n	22	20	000	000	NUM
cord-301856-71syce4n	22	21	years	year	NOUN
cord-301856-71syce4n	22	22	ago	ago	ADV
cord-301856-71syce4n	22	23	[	[	X
cord-301856-71syce4n	22	24	6	6	NUM
cord-301856-71syce4n	22	25	]	]	PUNCT
cord-301856-71syce4n	22	26	.	.	PUNCT
cord-301856-71syce4n	23	1	human	human	ADJ
cord-301856-71syce4n	23	2	evolution	evolution	NOUN
cord-301856-71syce4n	23	3	has	have	AUX
cord-301856-71syce4n	23	4	been	be	AUX
cord-301856-71syce4n	23	5	constantly	constantly	ADV
cord-301856-71syce4n	23	6	influenced	influence	VERB
cord-301856-71syce4n	23	7	by	by	ADP
cord-301856-71syce4n	23	8	pathogens	pathogen	NOUN
cord-301856-71syce4n	23	9	;	;	PUNCT
cord-301856-71syce4n	23	10	therefore	therefore	ADV
cord-301856-71syce4n	23	11	,	,	PUNCT
cord-301856-71syce4n	23	12	a	a	DET
cord-301856-71syce4n	23	13	great	great	ADJ
cord-301856-71syce4n	23	14	number	number	NOUN
cord-301856-71syce4n	23	15	of	of	ADP
cord-301856-71syce4n	23	16	human	human	ADJ
cord-301856-71syce4n	23	17	genes	gene	NOUN
cord-301856-71syce4n	23	18	linked	link	VERB
cord-301856-71syce4n	23	19	to	to	ADP
cord-301856-71syce4n	23	20	immune	immune	ADJ
cord-301856-71syce4n	23	21	functions	function	NOUN
cord-301856-71syce4n	23	22	and	and	CCONJ
cord-301856-71syce4n	23	23	immunity	immunity	NOUN
cord-301856-71syce4n	23	24	-	-	PUNCT
cord-301856-71syce4n	23	25	related	relate	VERB
cord-301856-71syce4n	23	26	disorders	disorder	NOUN
cord-301856-71syce4n	23	27	have	have	AUX
cord-301856-71syce4n	23	28	evolved	evolve	VERB
cord-301856-71syce4n	23	29	along	along	ADP
cord-301856-71syce4n	23	30	with	with	ADP
cord-301856-71syce4n	23	31	humans	human	NOUN
cord-301856-71syce4n	23	32	.	.	PUNCT
cord-301856-71syce4n	24	1	the	the	DET
cord-301856-71syce4n	24	2	heterogeneity	heterogeneity	NOUN
cord-301856-71syce4n	24	3	in	in	ADP
cord-301856-71syce4n	24	4	the	the	DET
cord-301856-71syce4n	24	5	immune	immune	ADJ
cord-301856-71syce4n	24	6	response	response	NOUN
cord-301856-71syce4n	24	7	to	to	ADP
cord-301856-71syce4n	24	8	infectious	infectious	ADJ
cord-301856-71syce4n	24	9	diseases	disease	NOUN
cord-301856-71syce4n	24	10	across	across	ADP
cord-301856-71syce4n	24	11	different	different	ADJ
cord-301856-71syce4n	24	12	populations	population	NOUN
cord-301856-71syce4n	24	13	is	be	AUX
cord-301856-71syce4n	24	14	under	under	ADP
cord-301856-71syce4n	24	15	genetic	genetic	ADJ
cord-301856-71syce4n	24	16	control	control	NOUN
cord-301856-71syce4n	24	17	and	and	CCONJ
cord-301856-71syce4n	24	18	is	be	AUX
cord-301856-71syce4n	24	19	the	the	DET
cord-301856-71syce4n	24	20	result	result	NOUN
cord-301856-71syce4n	24	21	of	of	ADP
cord-301856-71syce4n	24	22	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	24	23	processes	process	NOUN
cord-301856-71syce4n	24	24	.	.	PUNCT
cord-301856-71syce4n	25	1	genetic	genetic	ADJ
cord-301856-71syce4n	25	2	variants	variant	NOUN
cord-301856-71syce4n	25	3	that	that	PRON
cord-301856-71syce4n	25	4	have	have	AUX
cord-301856-71syce4n	25	5	been	be	AUX
cord-301856-71syce4n	25	6	under	under	ADP
cord-301856-71syce4n	25	7	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	25	8	pressure	pressure	NOUN
cord-301856-71syce4n	25	9	can	can	AUX
cord-301856-71syce4n	25	10	contribute	contribute	VERB
cord-301856-71syce4n	25	11	to	to	ADP
cord-301856-71syce4n	25	12	explaining	explain	VERB
cord-301856-71syce4n	25	13	the	the	DET
cord-301856-71syce4n	25	14	differences	difference	NOUN
cord-301856-71syce4n	25	15	in	in	ADP
cord-301856-71syce4n	25	16	the	the	DET
cord-301856-71syce4n	25	17	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	25	18	to	to	ADP
cord-301856-71syce4n	25	19	diseases	disease	NOUN
cord-301856-71syce4n	25	20	observed	observe	VERB
cord-301856-71syce4n	25	21	across	across	ADP
cord-301856-71syce4n	25	22	different	different	ADJ
cord-301856-71syce4n	25	23	populations	population	NOUN
cord-301856-71syce4n	25	24	.	.	PUNCT
cord-301856-71syce4n	26	1	the	the	DET
cord-301856-71syce4n	26	2	ancestry	ancestry	NOUN
cord-301856-71syce4n	26	3	of	of	ADP
cord-301856-71syce4n	26	4	individuals	individual	NOUN
cord-301856-71syce4n	26	5	from	from	ADP
cord-301856-71syce4n	26	6	different	different	ADJ
cord-301856-71syce4n	26	7	populations	population	NOUN
cord-301856-71syce4n	26	8	across	across	ADP
cord-301856-71syce4n	26	9	the	the	DET
cord-301856-71syce4n	26	10	globe	globe	NOUN
cord-301856-71syce4n	26	11	greatly	greatly	ADV
cord-301856-71syce4n	26	12	influences	influence	VERB
cord-301856-71syce4n	26	13	their	their	PRON
cord-301856-71syce4n	26	14	possibility	possibility	NOUN
cord-301856-71syce4n	26	15	of	of	ADP
cord-301856-71syce4n	26	16	developing	develop	VERB
cord-301856-71syce4n	26	17	certain	certain	ADJ
cord-301856-71syce4n	26	18	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	26	19	diseases	disease	NOUN
cord-301856-71syce4n	26	20	and	and	CCONJ
cord-301856-71syce4n	26	21	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	26	22	disorders	disorder	NOUN
cord-301856-71syce4n	26	23	.	.	PUNCT
cord-301856-71syce4n	27	1	the	the	DET
cord-301856-71syce4n	27	2	lifestyle	lifestyle	NOUN
cord-301856-71syce4n	27	3	of	of	ADP
cord-301856-71syce4n	27	4	western	western	ADJ
cord-301856-71syce4n	27	5	societies	society	NOUN
cord-301856-71syce4n	27	6	affects	affect	VERB
cord-301856-71syce4n	27	7	the	the	DET
cord-301856-71syce4n	27	8	symbiotic	symbiotic	ADJ
cord-301856-71syce4n	27	9	relationships	relationship	NOUN
cord-301856-71syce4n	27	10	between	between	ADP
cord-301856-71syce4n	27	11	humans	human	NOUN
cord-301856-71syce4n	27	12	,	,	PUNCT
cord-301856-71syce4n	27	13	viruses	virus	NOUN
cord-301856-71syce4n	27	14	,	,	PUNCT
cord-301856-71syce4n	27	15	and	and	CCONJ
cord-301856-71syce4n	27	16	other	other	ADJ
cord-301856-71syce4n	27	17	organisms	organism	NOUN
cord-301856-71syce4n	27	18	and	and	CCONJ
cord-301856-71syce4n	27	19	might	might	AUX
cord-301856-71syce4n	27	20	contribute	contribute	VERB
cord-301856-71syce4n	27	21	to	to	ADP
cord-301856-71syce4n	27	22	the	the	DET
cord-301856-71syce4n	27	23	rise	rise	NOUN
cord-301856-71syce4n	27	24	of	of	ADP
cord-301856-71syce4n	27	25	certain	certain	ADJ
cord-301856-71syce4n	27	26	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	27	27	and	and	CCONJ
cord-301856-71syce4n	27	28	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	27	29	diseases	disease	NOUN
cord-301856-71syce4n	27	30	.	.	PUNCT
cord-301856-71syce4n	28	1	pathogens	pathogen	NOUN
cord-301856-71syce4n	28	2	have	have	AUX
cord-301856-71syce4n	28	3	played	play	VERB
cord-301856-71syce4n	28	4	a	a	DET
cord-301856-71syce4n	28	5	central	central	ADJ
cord-301856-71syce4n	28	6	role	role	NOUN
cord-301856-71syce4n	28	7	as	as	ADP
cord-301856-71syce4n	28	8	agents	agent	NOUN
cord-301856-71syce4n	28	9	of	of	ADP
cord-301856-71syce4n	28	10	natural	natural	ADJ
cord-301856-71syce4n	28	11	selection	selection	NOUN
cord-301856-71syce4n	28	12	from	from	ADP
cord-301856-71syce4n	28	13	those	those	DET
cord-301856-71syce4n	28	14	very	very	ADV
cord-301856-71syce4n	28	15	early	early	ADJ
cord-301856-71syce4n	28	16	days	day	NOUN
cord-301856-71syce4n	28	17	.	.	PUNCT
cord-301856-71syce4n	29	1	among	among	ADP
cord-301856-71syce4n	29	2	various	various	ADJ
cord-301856-71syce4n	29	3	infectious	infectious	ADJ
cord-301856-71syce4n	29	4	diseases	disease	NOUN
cord-301856-71syce4n	29	5	,	,	PUNCT
cord-301856-71syce4n	29	6	malaria	malaria	NOUN
cord-301856-71syce4n	29	7	has	have	AUX
cord-301856-71syce4n	29	8	exerted	exert	VERB
cord-301856-71syce4n	29	9	the	the	DET
cord-301856-71syce4n	29	10	highest	high	ADJ
cord-301856-71syce4n	29	11	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	29	12	pressure	pressure	NOUN
cord-301856-71syce4n	29	13	on	on	ADP
cord-301856-71syce4n	29	14	the	the	DET
cord-301856-71syce4n	29	15	communities	community	NOUN
cord-301856-71syce4n	29	16	across	across	ADP
cord-301856-71syce4n	29	17	the	the	DET
cord-301856-71syce4n	29	18	african	african	ADJ
cord-301856-71syce4n	29	19	continent	continent	NOUN
cord-301856-71syce4n	29	20	(	(	PUNCT
cord-301856-71syce4n	29	21	figure	figure	NOUN
cord-301856-71syce4n	29	22	2	2	NUM
cord-301856-71syce4n	29	23	)	)	PUNCT
cord-301856-71syce4n	30	1	[	[	X
cord-301856-71syce4n	30	2	7	7	NUM
cord-301856-71syce4n	30	3	]	]	PUNCT
cord-301856-71syce4n	30	4	.	.	PUNCT
cord-301856-71syce4n	31	1	populations	population	NOUN
cord-301856-71syce4n	31	2	remaining	remain	VERB
cord-301856-71syce4n	31	3	in	in	ADP
cord-301856-71syce4n	31	4	sub	sub	ADJ
cord-301856-71syce4n	31	5	-	-	ADJ
cord-301856-71syce4n	31	6	saharan	saharan	ADJ
cord-301856-71syce4n	31	7	africa	africa	PROPN
cord-301856-71syce4n	31	8	have	have	AUX
cord-301856-71syce4n	31	9	been	be	AUX
cord-301856-71syce4n	31	10	exposed	expose	VERB
cord-301856-71syce4n	31	11	to	to	ADP
cord-301856-71syce4n	31	12	malaria	malaria	NOUN
cord-301856-71syce4n	31	13	for	for	ADP
cord-301856-71syce4n	31	14	such	such	ADJ
cord-301856-71syce4n	31	15	long	long	ADJ
cord-301856-71syce4n	31	16	periods	period	NOUN
cord-301856-71syce4n	31	17	of	of	ADP
cord-301856-71syce4n	31	18	time	time	NOUN
cord-301856-71syce4n	31	19	that	that	PRON
cord-301856-71syce4n	31	20	their	their	PRON
cord-301856-71syce4n	31	21	genetic	genetic	ADJ
cord-301856-71syce4n	31	22	structures	structure	NOUN
cord-301856-71syce4n	31	23	have	have	AUX
cord-301856-71syce4n	31	24	been	be	AUX
cord-301856-71syce4n	31	25	shaped	shape	VERB
cord-301856-71syce4n	31	26	by	by	ADP
cord-301856-71syce4n	31	27	the	the	DET
cord-301856-71syce4n	31	28	severity	severity	NOUN
cord-301856-71syce4n	31	29	of	of	ADP
cord-301856-71syce4n	31	30	malaria	malaria	NOUN
cord-301856-71syce4n	31	31	(	(	PUNCT
cord-301856-71syce4n	31	32	plasmodium	plasmodium	PROPN
cord-301856-71syce4n	31	33	sp	sp	NOUN
cord-301856-71syce4n	31	34	.	.	PUNCT
cord-301856-71syce4n	31	35	)	)	PUNCT
cord-301856-71syce4n	32	1	infections	infection	NOUN
cord-301856-71syce4n	32	2	.	.	PUNCT
cord-301856-71syce4n	33	1	in	in	ADP
cord-301856-71syce4n	33	2	1954	1954	NUM
cord-301856-71syce4n	33	3	,	,	PUNCT
cord-301856-71syce4n	33	4	allison	allison	PROPN
cord-301856-71syce4n	33	5	described	describe	VERB
cord-301856-71syce4n	33	6	that	that	SCONJ
cord-301856-71syce4n	33	7	sickle	sickle	ADJ
cord-301856-71syce4n	33	8	cell	cell	NOUN
cord-301856-71syce4n	33	9	disease	disease	NOUN
cord-301856-71syce4n	33	10	distribution	distribution	NOUN
cord-301856-71syce4n	33	11	was	be	AUX
cord-301856-71syce4n	33	12	confined	confine	VERB
cord-301856-71syce4n	33	13	to	to	ADP
cord-301856-71syce4n	33	14	africa	africa	PROPN
cord-301856-71syce4n	33	15	and	and	CCONJ
cord-301856-71syce4n	33	16	was	be	AUX
cord-301856-71syce4n	33	17	associated	associate	VERB
cord-301856-71syce4n	33	18	with	with	ADP
cord-301856-71syce4n	33	19	the	the	DET
cord-301856-71syce4n	33	20	geographical	geographical	ADJ
cord-301856-71syce4n	33	21	presence	presence	NOUN
cord-301856-71syce4n	33	22	of	of	ADP
cord-301856-71syce4n	33	23	malaria	malaria	NOUN
cord-301856-71syce4n	33	24	[	[	PUNCT
cord-301856-71syce4n	33	25	8	8	NUM
cord-301856-71syce4n	33	26	]	]	PUNCT
cord-301856-71syce4n	33	27	.	.	PUNCT
cord-301856-71syce4n	34	1	this	this	DET
cord-301856-71syce4n	34	2	finding	finding	NOUN
cord-301856-71syce4n	34	3	led	lead	VERB
cord-301856-71syce4n	34	4	to	to	ADP
cord-301856-71syce4n	34	5	the	the	DET
cord-301856-71syce4n	34	6	more	more	ADV
cord-301856-71syce4n	34	7	recent	recent	ADJ
cord-301856-71syce4n	34	8	description	description	NOUN
cord-301856-71syce4n	34	9	of	of	ADP
cord-301856-71syce4n	34	10	the	the	DET
cord-301856-71syce4n	34	11	existence	existence	NOUN
cord-301856-71syce4n	34	12	of	of	ADP
cord-301856-71syce4n	34	13	mutations	mutation	NOUN
cord-301856-71syce4n	34	14	in	in	ADP
cord-301856-71syce4n	34	15	the	the	DET
cord-301856-71syce4n	34	16	hemoglobin	hemoglobin	NOUN
cord-301856-71syce4n	34	17	-	-	PUNCT
cord-301856-71syce4n	34	18	b	b	PROPN
cord-301856-71syce4n	34	19	(	(	PUNCT
cord-301856-71syce4n	34	20	hbb	hbb	PROPN
cord-301856-71syce4n	34	21	)	)	PUNCT
cord-301856-71syce4n	34	22	gene	gene	NOUN
cord-301856-71syce4n	34	23	as	as	ADP
cord-301856-71syce4n	34	24	a	a	DET
cord-301856-71syce4n	34	25	result	result	NOUN
cord-301856-71syce4n	34	26	of	of	ADP
cord-301856-71syce4n	34	27	natural	natural	ADJ
cord-301856-71syce4n	34	28	selection	selection	NOUN
cord-301856-71syce4n	34	29	driven	drive	VERB
cord-301856-71syce4n	34	30	by	by	ADP
cord-301856-71syce4n	34	31	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	34	32	pressure	pressure	NOUN
cord-301856-71syce4n	34	33	for	for	ADP
cord-301856-71syce4n	34	34	protection	protection	NOUN
cord-301856-71syce4n	34	35	against	against	ADP
cord-301856-71syce4n	34	36	malaria	malaria	NOUN
cord-301856-71syce4n	34	37	[	[	X
cord-301856-71syce4n	34	38	9	9	NUM
cord-301856-71syce4n	34	39	]	]	X
cord-301856-71syce4n	34	40	(	(	PUNCT
cord-301856-71syce4n	34	41	table	table	NOUN
cord-301856-71syce4n	34	42	1	1	NUM
cord-301856-71syce4n	34	43	)	)	PUNCT
cord-301856-71syce4n	34	44	.	.	PUNCT
cord-301856-71syce4n	35	1	similarly	similarly	ADV
cord-301856-71syce4n	35	2	to	to	ADP
cord-301856-71syce4n	35	3	hbb	hbb	PROPN
cord-301856-71syce4n	35	4	,	,	PUNCT
cord-301856-71syce4n	35	5	some	some	DET
cord-301856-71syce4n	35	6	areas	area	NOUN
cord-301856-71syce4n	35	7	of	of	ADP
cord-301856-71syce4n	35	8	west	west	PROPN
cord-301856-71syce4n	35	9	africa	africa	PROPN
cord-301856-71syce4n	35	10	with	with	ADP
cord-301856-71syce4n	35	11	a	a	DET
cord-301856-71syce4n	35	12	high	high	ADJ
cord-301856-71syce4n	35	13	incidence	incidence	NOUN
cord-301856-71syce4n	35	14	of	of	ADP
cord-301856-71syce4n	35	15	malaria	malaria	NOUN
cord-301856-71syce4n	35	16	the	the	DET
cord-301856-71syce4n	35	17	gene	gene	NOUN
cord-301856-71syce4n	35	18	variations	variation	NOUN
cord-301856-71syce4n	35	19	that	that	PRON
cord-301856-71syce4n	35	20	pass	pass	VERB
cord-301856-71syce4n	35	21	from	from	ADP
cord-301856-71syce4n	35	22	one	one	NUM
cord-301856-71syce4n	35	23	generation	generation	NOUN
cord-301856-71syce4n	35	24	to	to	ADP
cord-301856-71syce4n	35	25	the	the	DET
cord-301856-71syce4n	35	26	next	next	ADJ
cord-301856-71syce4n	35	27	are	be	AUX
cord-301856-71syce4n	35	28	often	often	ADV
cord-301856-71syce4n	35	29	transmitted	transmit	VERB
cord-301856-71syce4n	35	30	as	as	ADP
cord-301856-71syce4n	35	31	a	a	DET
cord-301856-71syce4n	35	32	random	random	ADJ
cord-301856-71syce4n	35	33	process	process	NOUN
cord-301856-71syce4n	35	34	known	know	VERB
cord-301856-71syce4n	35	35	as	as	ADP
cord-301856-71syce4n	35	36	genetic	genetic	ADJ
cord-301856-71syce4n	35	37	drift	drift	NOUN
cord-301856-71syce4n	35	38	,	,	PUNCT
cord-301856-71syce4n	35	39	while	while	SCONJ
cord-301856-71syce4n	35	40	selection	selection	NOUN
cord-301856-71syce4n	35	41	of	of	ADP
cord-301856-71syce4n	35	42	advantageous	advantageous	ADJ
cord-301856-71syce4n	35	43	variants	variant	NOUN
cord-301856-71syce4n	35	44	tends	tend	VERB
cord-301856-71syce4n	35	45	to	to	PART
cord-301856-71syce4n	35	46	be	be	AUX
cord-301856-71syce4n	35	47	preferentially	preferentially	ADV
cord-301856-71syce4n	35	48	transmitted	transmit	VERB
cord-301856-71syce4n	35	49	.	.	PUNCT
cord-301856-71syce4n	36	1	mutations	mutation	NOUN
cord-301856-71syce4n	36	2	,	,	PUNCT
cord-301856-71syce4n	36	3	genetic	genetic	ADJ
cord-301856-71syce4n	36	4	drift	drift	NOUN
cord-301856-71syce4n	36	5	,	,	PUNCT
cord-301856-71syce4n	36	6	migration	migration	NOUN
cord-301856-71syce4n	36	7	,	,	PUNCT
cord-301856-71syce4n	36	8	and	and	CCONJ
cord-301856-71syce4n	36	9	environmental	environmental	ADJ
cord-301856-71syce4n	36	10	selective	selective	ADJ
cord-301856-71syce4n	36	11	pressure	pressure	NOUN
cord-301856-71syce4n	36	12	are	be	AUX
cord-301856-71syce4n	36	13	among	among	ADP
cord-301856-71syce4n	36	14	the	the	DET
cord-301856-71syce4n	36	15	fundamental	fundamental	ADJ
cord-301856-71syce4n	36	16	processes	process	NOUN
cord-301856-71syce4n	36	17	behind	behind	ADP
cord-301856-71syce4n	36	18	the	the	DET
cord-301856-71syce4n	36	19	evolution	evolution	NOUN
cord-301856-71syce4n	36	20	of	of	ADP
cord-301856-71syce4n	36	21	humans	human	NOUN
cord-301856-71syce4n	36	22	.	.	PUNCT
cord-301856-71syce4n	37	1	the	the	DET
cord-301856-71syce4n	37	2	influence	influence	NOUN
cord-301856-71syce4n	37	3	of	of	ADP
cord-301856-71syce4n	37	4	these	these	DET
cord-301856-71syce4n	37	5	mechanisms	mechanism	NOUN
cord-301856-71syce4n	37	6	in	in	ADP
cord-301856-71syce4n	37	7	the	the	DET
cord-301856-71syce4n	37	8	diverse	diverse	ADJ
cord-301856-71syce4n	37	9	communities	community	NOUN
cord-301856-71syce4n	37	10	that	that	PRON
cord-301856-71syce4n	37	11	were	be	AUX
cord-301856-71syce4n	37	12	mobilized	mobilize	VERB
cord-301856-71syce4n	37	13	and	and	CCONJ
cord-301856-71syce4n	37	14	then	then	ADV
cord-301856-71syce4n	37	15	became	become	VERB
cord-301856-71syce4n	37	16	isolated	isolated	ADJ
cord-301856-71syce4n	37	17	,	,	PUNCT
cord-301856-71syce4n	37	18	as	as	ADV
cord-301856-71syce4n	37	19	well	well	ADV
cord-301856-71syce4n	37	20	as	as	ADP
cord-301856-71syce4n	37	21	severe	severe	ADJ
cord-301856-71syce4n	37	22	external	external	ADJ
cord-301856-71syce4n	37	23	factors	factor	NOUN
cord-301856-71syce4n	37	24	such	such	ADJ
cord-301856-71syce4n	37	25	as	as	ADP
cord-301856-71syce4n	37	26	epidemics	epidemic	NOUN
cord-301856-71syce4n	37	27	,	,	PUNCT
cord-301856-71syce4n	37	28	caused	cause	VERB
cord-301856-71syce4n	37	29	successive	successive	ADJ
cord-301856-71syce4n	37	30	genetic	genetic	ADJ
cord-301856-71syce4n	37	31	bottlenecks	bottleneck	NOUN
cord-301856-71syce4n	37	32	in	in	ADP
cord-301856-71syce4n	37	33	populations	population	NOUN
cord-301856-71syce4n	37	34	(	(	PUNCT
cord-301856-71syce4n	37	35	see	see	VERB
cord-301856-71syce4n	37	36	figure	figure	NOUN
cord-301856-71syce4n	37	37	1	1	NUM
cord-301856-71syce4n	37	38	in	in	ADP
cord-301856-71syce4n	37	39	main	main	ADJ
cord-301856-71syce4n	37	40	text	text	NOUN
cord-301856-71syce4n	37	41	)	)	PUNCT
cord-301856-71syce4n	38	1	[	[	X
cord-301856-71syce4n	38	2	90	90	NUM
cord-301856-71syce4n	38	3	]	]	PUNCT
cord-301856-71syce4n	38	4	.	.	PUNCT
cord-301856-71syce4n	39	1	human	human	ADJ
cord-301856-71syce4n	39	2	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	39	3	studies	study	NOUN
cord-301856-71syce4n	39	4	are	be	AUX
cord-301856-71syce4n	39	5	currently	currently	ADV
cord-301856-71syce4n	39	6	considered	consider	VERB
cord-301856-71syce4n	39	7	under	under	ADP
cord-301856-71syce4n	39	8	'	'	PUNCT
cord-301856-71syce4n	39	9	modern	modern	ADJ
cord-301856-71syce4n	39	10	synthesis	synthesis	NOUN
cord-301856-71syce4n	39	11	'	'	PUNCT
cord-301856-71syce4n	39	12	,	,	PUNCT
cord-301856-71syce4n	39	13	which	which	PRON
cord-301856-71syce4n	39	14	merges	merge	VERB
cord-301856-71syce4n	39	15	darwin	darwin	PROPN
cord-301856-71syce4n	39	16	's	's	PART
cord-301856-71syce4n	39	17	ideas	idea	NOUN
cord-301856-71syce4n	39	18	of	of	ADP
cord-301856-71syce4n	39	19	natural	natural	ADJ
cord-301856-71syce4n	39	20	selection	selection	NOUN
cord-301856-71syce4n	39	21	with	with	ADP
cord-301856-71syce4n	39	22	theoretical	theoretical	ADJ
cord-301856-71syce4n	39	23	population	population	NOUN
cord-301856-71syce4n	39	24	genetics	genetic	NOUN
cord-301856-71syce4n	39	25	and	and	CCONJ
cord-301856-71syce4n	39	26	mendelian	mendelian	ADJ
cord-301856-71syce4n	39	27	principles	principle	NOUN
cord-301856-71syce4n	39	28	,	,	PUNCT
cord-301856-71syce4n	39	29	stating	state	VERB
cord-301856-71syce4n	39	30	that	that	SCONJ
cord-301856-71syce4n	39	31	evolution	evolution	NOUN
cord-301856-71syce4n	39	32	occurs	occur	VERB
cord-301856-71syce4n	39	33	via	via	ADP
cord-301856-71syce4n	39	34	small	small	ADJ
cord-301856-71syce4n	39	35	genetic	genetic	ADJ
cord-301856-71syce4n	39	36	changes	change	NOUN
cord-301856-71syce4n	39	37	that	that	PRON
cord-301856-71syce4n	39	38	are	be	AUX
cord-301856-71syce4n	39	39	regulated	regulate	VERB
cord-301856-71syce4n	39	40	by	by	ADP
cord-301856-71syce4n	39	41	natural	natural	ADJ
cord-301856-71syce4n	39	42	selection	selection	NOUN
cord-301856-71syce4n	39	43	[	[	X
cord-301856-71syce4n	39	44	91	91	NUM
cord-301856-71syce4n	39	45	]	]	PUNCT
cord-301856-71syce4n	39	46	.	.	PUNCT
cord-301856-71syce4n	40	1	these	these	DET
cord-301856-71syce4n	40	2	beneficial	beneficial	ADJ
cord-301856-71syce4n	40	3	adaptations	adaptation	NOUN
cord-301856-71syce4n	40	4	subsequently	subsequently	ADV
cord-301856-71syce4n	40	5	expand	expand	VERB
cord-301856-71syce4n	40	6	within	within	ADP
cord-301856-71syce4n	40	7	the	the	DET
cord-301856-71syce4n	40	8	members	member	NOUN
cord-301856-71syce4n	40	9	of	of	ADP
cord-301856-71syce4n	40	10	a	a	DET
cord-301856-71syce4n	40	11	population	population	NOUN
cord-301856-71syce4n	40	12	and	and	CCONJ
cord-301856-71syce4n	40	13	become	become	VERB
cord-301856-71syce4n	40	14	evident	evident	ADJ
cord-301856-71syce4n	40	15	in	in	ADP
cord-301856-71syce4n	40	16	the	the	DET
cord-301856-71syce4n	40	17	ancestral	ancestral	ADJ
cord-301856-71syce4n	40	18	specificity	specificity	NOUN
cord-301856-71syce4n	40	19	and	and	CCONJ
cord-301856-71syce4n	40	20	the	the	DET
cord-301856-71syce4n	40	21	geographical	geographical	ADJ
cord-301856-71syce4n	40	22	distribution	distribution	NOUN
cord-301856-71syce4n	40	23	of	of	ADP
cord-301856-71syce4n	40	24	the	the	DET
cord-301856-71syce4n	40	25	advantageous	advantageous	ADJ
cord-301856-71syce4n	40	26	alleles	allele	NOUN
cord-301856-71syce4n	40	27	in	in	ADP
cord-301856-71syce4n	40	28	the	the	DET
cord-301856-71syce4n	40	29	genomes	genome	NOUN
cord-301856-71syce4n	40	30	of	of	ADP
cord-301856-71syce4n	40	31	contemporary	contemporary	ADJ
cord-301856-71syce4n	40	32	humans	human	NOUN
cord-301856-71syce4n	40	33	.	.	PUNCT
cord-301856-71syce4n	41	1	genetic	genetic	ADJ
cord-301856-71syce4n	41	2	bottlenecks	bottleneck	NOUN
cord-301856-71syce4n	41	3	occur	occur	VERB
cord-301856-71syce4n	41	4	when	when	SCONJ
cord-301856-71syce4n	41	5	the	the	DET
cord-301856-71syce4n	41	6	number	number	NOUN
cord-301856-71syce4n	41	7	of	of	ADP
cord-301856-71syce4n	41	8	individuals	individual	NOUN
cord-301856-71syce4n	41	9	in	in	ADP
cord-301856-71syce4n	41	10	a	a	DET
cord-301856-71syce4n	41	11	population	population	NOUN
cord-301856-71syce4n	41	12	is	be	AUX
cord-301856-71syce4n	41	13	reduced	reduce	VERB
cord-301856-71syce4n	41	14	drastically	drastically	ADV
cord-301856-71syce4n	41	15	due	due	ADP
cord-301856-71syce4n	41	16	to	to	ADP
cord-301856-71syce4n	41	17	a	a	DET
cord-301856-71syce4n	41	18	catastrophic	catastrophic	ADJ
cord-301856-71syce4n	41	19	event	event	NOUN
cord-301856-71syce4n	41	20	such	such	ADJ
cord-301856-71syce4n	41	21	as	as	ADP
cord-301856-71syce4n	41	22	an	an	DET
cord-301856-71syce4n	41	23	earthquake	earthquake	NOUN
cord-301856-71syce4n	41	24	,	,	PUNCT
cord-301856-71syce4n	41	25	a	a	DET
cord-301856-71syce4n	41	26	flood	flood	NOUN
cord-301856-71syce4n	41	27	,	,	PUNCT
cord-301856-71syce4n	41	28	a	a	DET
cord-301856-71syce4n	41	29	famine	famine	NOUN
cord-301856-71syce4n	41	30	,	,	PUNCT
cord-301856-71syce4n	41	31	or	or	CCONJ
cord-301856-71syce4n	41	32	the	the	DET
cord-301856-71syce4n	41	33	outbreak	outbreak	NOUN
cord-301856-71syce4n	41	34	of	of	ADP
cord-301856-71syce4n	41	35	an	an	DET
cord-301856-71syce4n	41	36	infectious	infectious	ADJ
cord-301856-71syce4n	41	37	disease	disease	NOUN
cord-301856-71syce4n	41	38	.	.	PUNCT
cord-301856-71syce4n	42	1	these	these	DET
cord-301856-71syce4n	42	2	events	event	NOUN
cord-301856-71syce4n	42	3	limit	limit	VERB
cord-301856-71syce4n	42	4	the	the	DET
cord-301856-71syce4n	42	5	genetic	genetic	ADJ
cord-301856-71syce4n	42	6	variation	variation	NOUN
cord-301856-71syce4n	42	7	of	of	ADP
cord-301856-71syce4n	42	8	a	a	DET
cord-301856-71syce4n	42	9	population	population	NOUN
cord-301856-71syce4n	42	10	and	and	CCONJ
cord-301856-71syce4n	42	11	can	can	AUX
cord-301856-71syce4n	42	12	lead	lead	VERB
cord-301856-71syce4n	42	13	to	to	ADP
cord-301856-71syce4n	42	14	genetic	genetic	ADJ
cord-301856-71syce4n	42	15	drift	drift	NOUN
cord-301856-71syce4n	42	16	.	.	PUNCT
cord-301856-71syce4n	43	1	as	as	ADP
cord-301856-71syce4n	43	2	a	a	DET
cord-301856-71syce4n	43	3	result	result	NOUN
cord-301856-71syce4n	43	4	,	,	PUNCT
cord-301856-71syce4n	43	5	a	a	DET
cord-301856-71syce4n	43	6	smaller	small	ADJ
cord-301856-71syce4n	43	7	population	population	NOUN
cord-301856-71syce4n	43	8	,	,	PUNCT
cord-301856-71syce4n	43	9	with	with	ADP
cord-301856-71syce4n	43	10	a	a	DET
cord-301856-71syce4n	43	11	correspondingly	correspondingly	ADV
cord-301856-71syce4n	43	12	reduced	reduce	VERB
cord-301856-71syce4n	43	13	genetic	genetic	ADJ
cord-301856-71syce4n	43	14	diversity	diversity	NOUN
cord-301856-71syce4n	43	15	,	,	PUNCT
cord-301856-71syce4n	43	16	remains	remain	VERB
cord-301856-71syce4n	43	17	to	to	PART
cord-301856-71syce4n	43	18	transmit	transmit	VERB
cord-301856-71syce4n	43	19	genes	gene	NOUN
cord-301856-71syce4n	43	20	to	to	ADP
cord-301856-71syce4n	43	21	future	future	ADJ
cord-301856-71syce4n	43	22	generations	generation	NOUN
cord-301856-71syce4n	43	23	through	through	ADP
cord-301856-71syce4n	43	24	sexual	sexual	ADJ
cord-301856-71syce4n	43	25	reproduction	reproduction	NOUN
cord-301856-71syce4n	43	26	.	.	PUNCT
cord-301856-71syce4n	44	1	even	even	ADV
cord-301856-71syce4n	44	2	if	if	SCONJ
cord-301856-71syce4n	44	3	this	this	DET
cord-301856-71syce4n	44	4	reduction	reduction	NOUN
cord-301856-71syce4n	44	5	in	in	ADP
cord-301856-71syce4n	44	6	the	the	DET
cord-301856-71syce4n	44	7	genetic	genetic	ADJ
cord-301856-71syce4n	44	8	diversity	diversity	NOUN
cord-301856-71syce4n	44	9	is	be	AUX
cord-301856-71syce4n	44	10	temporary	temporary	ADJ
cord-301856-71syce4n	44	11	,	,	PUNCT
cord-301856-71syce4n	44	12	it	it	PRON
cord-301856-71syce4n	44	13	can	can	AUX
cord-301856-71syce4n	44	14	lead	lead	VERB
cord-301856-71syce4n	44	15	to	to	ADP
cord-301856-71syce4n	44	16	long	long	ADV
cord-301856-71syce4n	44	17	-	-	PUNCT
cord-301856-71syce4n	44	18	lasting	last	VERB
cord-301856-71syce4n	44	19	effects	effect	NOUN
cord-301856-71syce4n	44	20	on	on	ADP
cord-301856-71syce4n	44	21	the	the	DET
cord-301856-71syce4n	44	22	genetic	genetic	ADJ
cord-301856-71syce4n	44	23	variation	variation	NOUN
cord-301856-71syce4n	44	24	of	of	ADP
cord-301856-71syce4n	44	25	the	the	DET
cord-301856-71syce4n	44	26	offspring	offspring	NOUN
cord-301856-71syce4n	44	27	populations	population	NOUN
cord-301856-71syce4n	44	28	.	.	PUNCT
cord-301856-71syce4n	45	1	genetic	genetic	ADJ
cord-301856-71syce4n	45	2	drift	drift	NOUN
cord-301856-71syce4n	45	3	:	:	PUNCT
cord-301856-71syce4n	45	4	changes	change	NOUN
cord-301856-71syce4n	45	5	in	in	ADP
cord-301856-71syce4n	45	6	the	the	DET
cord-301856-71syce4n	45	7	allele	allele	ADJ
cord-301856-71syce4n	45	8	frequencies	frequency	NOUN
cord-301856-71syce4n	45	9	of	of	ADP
cord-301856-71syce4n	45	10	a	a	DET
cord-301856-71syce4n	45	11	population	population	NOUN
cord-301856-71syce4n	45	12	over	over	ADP
cord-301856-71syce4n	45	13	generations	generation	NOUN
cord-301856-71syce4n	45	14	due	due	ADP
cord-301856-71syce4n	45	15	to	to	ADP
cord-301856-71syce4n	45	16	chance	chance	NOUN
cord-301856-71syce4n	45	17	.	.	PUNCT
cord-301856-71syce4n	46	1	genetic	genetic	ADJ
cord-301856-71syce4n	46	2	locus	locus	PROPN
cord-301856-71syce4n	46	3	:	:	PUNCT
cord-301856-71syce4n	46	4	fixed	fix	VERB
cord-301856-71syce4n	46	5	position	position	NOUN
cord-301856-71syce4n	46	6	on	on	ADP
cord-301856-71syce4n	46	7	a	a	DET
cord-301856-71syce4n	46	8	chromosome	chromosome	NOUN
cord-301856-71syce4n	46	9	(	(	PUNCT
cord-301856-71syce4n	46	10	e.g.	e.g.	ADV
cord-301856-71syce4n	46	11	,	,	PUNCT
cord-301856-71syce4n	46	12	the	the	DET
cord-301856-71syce4n	46	13	position	position	NOUN
cord-301856-71syce4n	46	14	of	of	ADP
cord-301856-71syce4n	46	15	a	a	DET
cord-301856-71syce4n	46	16	gene	gene	NOUN
cord-301856-71syce4n	46	17	or	or	CCONJ
cord-301856-71syce4n	46	18	a	a	DET
cord-301856-71syce4n	46	19	genetic	genetic	ADJ
cord-301856-71syce4n	46	20	marker	marker	NOUN
cord-301856-71syce4n	46	21	)	)	PUNCT
cord-301856-71syce4n	46	22	.	.	PUNCT
cord-301856-71syce4n	47	1	histocompatibility	histocompatibility	NOUN
cord-301856-71syce4n	47	2	complex	complex	NOUN
cord-301856-71syce4n	47	3	:	:	PUNCT
cord-301856-71syce4n	47	4	region	region	NOUN
cord-301856-71syce4n	47	5	of	of	ADP
cord-301856-71syce4n	47	6	approximately	approximately	ADV
cord-301856-71syce4n	47	7	4000	4000	NUM
cord-301856-71syce4n	47	8	kb	kb	NOUN
cord-301856-71syce4n	47	9	,	,	PUNCT
cord-301856-71syce4n	47	10	located	locate	VERB
cord-301856-71syce4n	47	11	on	on	ADP
cord-301856-71syce4n	47	12	human	human	ADJ
cord-301856-71syce4n	47	13	chromosome	chromosome	NOUN
cord-301856-71syce4n	47	14	6	6	NUM
cord-301856-71syce4n	47	15	,	,	PUNCT
cord-301856-71syce4n	47	16	that	that	PRON
cord-301856-71syce4n	47	17	contains	contain	VERB
cord-301856-71syce4n	47	18	a	a	DET
cord-301856-71syce4n	47	19	large	large	ADJ
cord-301856-71syce4n	47	20	number	number	NOUN
cord-301856-71syce4n	47	21	of	of	ADP
cord-301856-71syce4n	47	22	genes	gene	NOUN
cord-301856-71syce4n	47	23	whose	whose	DET
cord-301856-71syce4n	47	24	products	product	NOUN
cord-301856-71syce4n	47	25	are	be	AUX
cord-301856-71syce4n	47	26	expressed	express	VERB
cord-301856-71syce4n	47	27	as	as	ADP
cord-301856-71syce4n	47	28	proteins	protein	NOUN
cord-301856-71syce4n	47	29	on	on	ADP
cord-301856-71syce4n	47	30	immune	immune	ADJ
cord-301856-71syce4n	47	31	cells	cell	NOUN
cord-301856-71syce4n	47	32	.	.	PUNCT
cord-301856-71syce4n	48	1	of	of	ADP
cord-301856-71syce4n	48	2	these	these	DET
cord-301856-71syce4n	48	3	genes	gene	NOUN
cord-301856-71syce4n	48	4	,	,	PUNCT
cord-301856-71syce4n	48	5	the	the	DET
cord-301856-71syce4n	48	6	best	well	ADV
cord-301856-71syce4n	48	7	known	know	VERB
cord-301856-71syce4n	48	8	are	be	AUX
cord-301856-71syce4n	48	9	hla	hla	PROPN
cord-301856-71syce4n	48	10	genes	genes	PROPN
cord-301856-71syce4n	48	11	.	.	PUNCT
cord-301856-71syce4n	49	1	introgressive	introgressive	PROPN
cord-301856-71syce4n	49	2	hybridization	hybridization	PROPN
cord-301856-71syce4n	49	3	:	:	PUNCT
cord-301856-71syce4n	49	4	incorporation	incorporation	NOUN
cord-301856-71syce4n	49	5	of	of	ADP
cord-301856-71syce4n	49	6	genes	gene	NOUN
cord-301856-71syce4n	49	7	from	from	ADP
cord-301856-71syce4n	49	8	one	one	NUM
cord-301856-71syce4n	49	9	species	specie	NOUN
cord-301856-71syce4n	49	10	into	into	ADP
cord-301856-71syce4n	49	11	the	the	DET
cord-301856-71syce4n	49	12	genetic	genetic	ADJ
cord-301856-71syce4n	49	13	reserves	reserve	NOUN
cord-301856-71syce4n	49	14	of	of	ADP
cord-301856-71syce4n	49	15	another	another	PRON
cord-301856-71syce4n	49	16	by	by	ADP
cord-301856-71syce4n	49	17	interspecific	interspecific	ADJ
cord-301856-71syce4n	49	18	hybridization	hybridization	NOUN
cord-301856-71syce4n	49	19	and	and	CCONJ
cord-301856-71syce4n	49	20	backcrossing	backcrossing	NOUN
cord-301856-71syce4n	49	21	with	with	ADP
cord-301856-71syce4n	49	22	the	the	DET
cord-301856-71syce4n	49	23	parent	parent	NOUN
cord-301856-71syce4n	49	24	species	specie	NOUN
cord-301856-71syce4n	49	25	.	.	PUNCT
cord-301856-71syce4n	50	1	present	present	VERB
cord-301856-71syce4n	50	2	a	a	DET
cord-301856-71syce4n	50	3	high	high	ADJ
cord-301856-71syce4n	50	4	frequency	frequency	NOUN
cord-301856-71syce4n	50	5	of	of	ADP
cord-301856-71syce4n	50	6	hemoglobin	hemoglobin	NOUN
cord-301856-71syce4n	50	7	-	-	PUNCT
cord-301856-71syce4n	50	8	c	c	PROPN
cord-301856-71syce4n	50	9	(	(	PUNCT
cord-301856-71syce4n	50	10	hbc	hbc	PROPN
cord-301856-71syce4n	50	11	)	)	PUNCT
cord-301856-71syce4n	50	12	in	in	ADP
cord-301856-71syce4n	50	13	their	their	PRON
cord-301856-71syce4n	50	14	populations	population	NOUN
cord-301856-71syce4n	50	15	,	,	PUNCT
cord-301856-71syce4n	50	16	which	which	PRON
cord-301856-71syce4n	50	17	is	be	AUX
cord-301856-71syce4n	50	18	associated	associate	VERB
cord-301856-71syce4n	50	19	with	with	ADP
cord-301856-71syce4n	50	20	a	a	DET
cord-301856-71syce4n	50	21	30	30	NUM
cord-301856-71syce4n	50	22	-	-	SYM
cord-301856-71syce4n	50	23	93	93	NUM
cord-301856-71syce4n	50	24	%	%	NOUN
cord-301856-71syce4n	50	25	decrease	decrease	NOUN
cord-301856-71syce4n	50	26	in	in	ADP
cord-301856-71syce4n	50	27	the	the	DET
cord-301856-71syce4n	50	28	possibility	possibility	NOUN
cord-301856-71syce4n	50	29	of	of	ADP
cord-301856-71syce4n	50	30	developing	develop	VERB
cord-301856-71syce4n	50	31	the	the	DET
cord-301856-71syce4n	50	32	disease	disease	NOUN
cord-301856-71syce4n	51	1	[	[	X
cord-301856-71syce4n	51	2	10	10	NUM
cord-301856-71syce4n	51	3	]	]	PUNCT
cord-301856-71syce4n	51	4	.	.	PUNCT
cord-301856-71syce4n	52	1	this	this	PRON
cord-301856-71syce4n	52	2	is	be	AUX
cord-301856-71syce4n	52	3	also	also	ADV
cord-301856-71syce4n	52	4	the	the	DET
cord-301856-71syce4n	52	5	case	case	NOUN
cord-301856-71syce4n	52	6	for	for	ADP
cord-301856-71syce4n	52	7	the	the	DET
cord-301856-71syce4n	52	8	duffy	duffy	ADJ
cord-301856-71syce4n	52	9	antigen	antigen	PROPN
cord-301856-71syce4n	52	10	receptor	receptor	NOUN
cord-301856-71syce4n	52	11	gene	gene	NOUN
cord-301856-71syce4n	52	12	(	(	PUNCT
cord-301856-71syce4n	52	13	darc	darc	PROPN
cord-301856-71syce4n	52	14	)	)	PUNCT
cord-301856-71syce4n	52	15	in	in	ADP
cord-301856-71syce4n	52	16	erythrocytes	erythrocyte	NOUN
cord-301856-71syce4n	52	17	and	and	CCONJ
cord-301856-71syce4n	52	18	single	single	ADJ
cord-301856-71syce4n	52	19	nucleotide	nucleotide	NOUN
cord-301856-71syce4n	52	20	polymorphisms	polymorphism	NOUN
cord-301856-71syce4n	52	21	(	(	PUNCT
cord-301856-71syce4n	52	22	snps	snps	PROPN
cord-301856-71syce4n	52	23	)	)	PUNCT
cord-301856-71syce4n	52	24	in	in	ADP
cord-301856-71syce4n	52	25	human	human	ADJ
cord-301856-71syce4n	52	26	leukocyte	leukocyte	NOUN
cord-301856-71syce4n	52	27	antigen	antigen	NOUN
cord-301856-71syce4n	52	28	(	(	PUNCT
cord-301856-71syce4n	52	29	hla	hla	PROPN
cord-301856-71syce4n	52	30	)	)	PUNCT
cord-301856-71syce4n	52	31	,	,	PUNCT
cord-301856-71syce4n	52	32	which	which	PRON
cord-301856-71syce4n	52	33	have	have	AUX
cord-301856-71syce4n	52	34	been	be	AUX
cord-301856-71syce4n	52	35	associated	associate	VERB
cord-301856-71syce4n	52	36	with	with	ADP
cord-301856-71syce4n	52	37	protection	protection	NOUN
cord-301856-71syce4n	52	38	against	against	ADP
cord-301856-71syce4n	52	39	plasmodium	plasmodium	PROPN
cord-301856-71syce4n	52	40	vivax	vivax	PROPN
cord-301856-71syce4n	52	41	malaria	malaria	NOUN
cord-301856-71syce4n	52	42	in	in	ADP
cord-301856-71syce4n	52	43	certain	certain	ADJ
cord-301856-71syce4n	52	44	areas	area	NOUN
cord-301856-71syce4n	52	45	of	of	ADP
cord-301856-71syce4n	52	46	africa	africa	PROPN
cord-301856-71syce4n	52	47	where	where	SCONJ
cord-301856-71syce4n	52	48	this	this	DET
cord-301856-71syce4n	52	49	disease	disease	NOUN
cord-301856-71syce4n	52	50	is	be	AUX
cord-301856-71syce4n	52	51	endemic	endemic	ADJ
cord-301856-71syce4n	52	52	[	[	ADP
cord-301856-71syce4n	52	53	11	11	NUM
cord-301856-71syce4n	52	54	,	,	PUNCT
cord-301856-71syce4n	52	55	12	12	NUM
cord-301856-71syce4n	52	56	]	]	PUNCT
cord-301856-71syce4n	52	57	.	.	PUNCT
cord-301856-71syce4n	53	1	another	another	DET
cord-301856-71syce4n	53	2	example	example	NOUN
cord-301856-71syce4n	53	3	of	of	ADP
cord-301856-71syce4n	53	4	natural	natural	ADJ
cord-301856-71syce4n	53	5	selection	selection	NOUN
cord-301856-71syce4n	53	6	driven	drive	VERB
cord-301856-71syce4n	53	7	by	by	ADP
cord-301856-71syce4n	53	8	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	53	9	pressure	pressure	NOUN
cord-301856-71syce4n	53	10	for	for	ADP
cord-301856-71syce4n	53	11	protection	protection	NOUN
cord-301856-71syce4n	53	12	against	against	ADP
cord-301856-71syce4n	53	13	malaria	malaria	NOUN
cord-301856-71syce4n	53	14	are	be	AUX
cord-301856-71syce4n	53	15	thalassemia	thalassemia	NOUN
cord-301856-71syce4n	53	16	(	(	PUNCT
cord-301856-71syce4n	53	17	a	a	PRON
cord-301856-71syce4n	53	18	and	and	CCONJ
cord-301856-71syce4n	53	19	b	b	NOUN
cord-301856-71syce4n	53	20	)	)	PUNCT
cord-301856-71syce4n	53	21	pathologies	pathology	NOUN
cord-301856-71syce4n	53	22	,	,	PUNCT
cord-301856-71syce4n	53	23	a	a	DET
cord-301856-71syce4n	53	24	group	group	NOUN
cord-301856-71syce4n	53	25	of	of	ADP
cord-301856-71syce4n	53	26	hemoglobin	hemoglobin	NOUN
cord-301856-71syce4n	53	27	disorders	disorder	NOUN
cord-301856-71syce4n	53	28	that	that	PRON
cord-301856-71syce4n	53	29	presents	present	VERB
cord-301856-71syce4n	53	30	an	an	DET
cord-301856-71syce4n	53	31	incidence	incidence	NOUN
cord-301856-71syce4n	53	32	of	of	ADP
cord-301856-71syce4n	53	33	up	up	ADP
cord-301856-71syce4n	53	34	to	to	PART
cord-301856-71syce4n	53	35	30	30	NUM
cord-301856-71syce4n	53	36	%	%	NOUN
cord-301856-71syce4n	53	37	among	among	ADP
cord-301856-71syce4n	53	38	communities	community	NOUN
cord-301856-71syce4n	53	39	of	of	ADP
cord-301856-71syce4n	53	40	west	west	PROPN
cord-301856-71syce4n	53	41	africa	africa	PROPN
cord-301856-71syce4n	54	1	[	[	PUNCT
cord-301856-71syce4n	54	2	13	13	NUM
cord-301856-71syce4n	54	3	]	]	PUNCT
cord-301856-71syce4n	54	4	.	.	PUNCT
cord-301856-71syce4n	55	1	the	the	DET
cord-301856-71syce4n	55	2	human	human	PROPN
cord-301856-71syce4n	55	3	casp12	casp12	NOUN
cord-301856-71syce4n	55	4	t	t	PROPN
cord-301856-71syce4n	55	5	125	125	NUM
cord-301856-71syce4n	55	6	c	c	PROPN
cord-301856-71syce4n	55	7	snp	snp	PROPN
cord-301856-71syce4n	55	8	,	,	PUNCT
cord-301856-71syce4n	55	9	expression	expression	NOUN
cord-301856-71syce4n	55	10	of	of	ADP
cord-301856-71syce4n	55	11	which	which	PRON
cord-301856-71syce4n	55	12	is	be	AUX
cord-301856-71syce4n	55	13	restricted	restrict	VERB
cord-301856-71syce4n	55	14	to	to	ADP
cord-301856-71syce4n	55	15	the	the	DET
cord-301856-71syce4n	55	16	african	african	ADJ
cord-301856-71syce4n	55	17	subcontinent	subcontinent	PROPN
cord-301856-71syce4n	55	18	,	,	PUNCT
cord-301856-71syce4n	55	19	south	south	PROPN
cord-301856-71syce4n	55	20	america	america	PROPN
cord-301856-71syce4n	55	21	,	,	PUNCT
cord-301856-71syce4n	55	22	and	and	CCONJ
cord-301856-71syce4n	55	23	certain	certain	ADJ
cord-301856-71syce4n	55	24	areas	area	NOUN
cord-301856-71syce4n	55	25	of	of	ADP
cord-301856-71syce4n	55	26	asia	asia	PROPN
cord-301856-71syce4n	55	27	,	,	PUNCT
cord-301856-71syce4n	55	28	can	can	AUX
cord-301856-71syce4n	55	29	modulate	modulate	VERB
cord-301856-71syce4n	55	30	immune	immune	ADJ
cord-301856-71syce4n	55	31	and	and	CCONJ
cord-301856-71syce4n	55	32	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	55	33	responses	response	NOUN
cord-301856-71syce4n	55	34	to	to	ADP
cord-301856-71syce4n	55	35	malaria	malaria	NOUN
cord-301856-71syce4n	55	36	by	by	ADP
cord-301856-71syce4n	55	37	antagonizing	antagonize	VERB
cord-301856-71syce4n	55	38	interleukin	interleukin	NOUN
cord-301856-71syce4n	55	39	(	(	PUNCT
cord-301856-71syce4n	55	40	il)-1b	il)-1b	PROPN
cord-301856-71syce4n	55	41	and	and	CCONJ
cord-301856-71syce4n	55	42	nf	nf	PROPN
cord-301856-71syce4n	55	43	-	-	PUNCT
cord-301856-71syce4n	55	44	kb	kb	PROPN
cord-301856-71syce4n	55	45	signaling	signaling	NOUN
cord-301856-71syce4n	55	46	in	in	ADP
cord-301856-71syce4n	55	47	innate	innate	ADJ
cord-301856-71syce4n	55	48	immune	immune	ADJ
cord-301856-71syce4n	55	49	cells	cell	NOUN
cord-301856-71syce4n	55	50	;	;	PUNCT
cord-301856-71syce4n	55	51	moreover	moreover	ADV
cord-301856-71syce4n	55	52	,	,	PUNCT
cord-301856-71syce4n	55	53	caspase	caspase	NOUN
cord-301856-71syce4n	55	54	12	12	NUM
cord-301856-71syce4n	55	55	-	-	PUNCT
cord-301856-71syce4n	55	56	deficient	deficient	ADJ
cord-301856-71syce4n	55	57	mice	mouse	NOUN
cord-301856-71syce4n	55	58	(	(	PUNCT
cord-301856-71syce4n	55	59	casp12	casp12	NOUN
cord-301856-71syce4n	55	60	-/-	-/-	NOUN
cord-301856-71syce4n	55	61	)	)	PUNCT
cord-301856-71syce4n	55	62	exhibit	exhibit	NOUN
cord-301856-71syce4n	55	63	decreased	decrease	VERB
cord-301856-71syce4n	55	64	interferon	interferon	NOUN
cord-301856-71syce4n	55	65	(	(	PUNCT
cord-301856-71syce4n	55	66	ifn)-g	ifn)-g	ADJ
cord-301856-71syce4n	55	67	production	production	NOUN
cord-301856-71syce4n	55	68	and	and	CCONJ
cord-301856-71syce4n	55	69	clearance	clearance	NOUN
cord-301856-71syce4n	55	70	of	of	ADP
cord-301856-71syce4n	55	71	the	the	DET
cord-301856-71syce4n	55	72	parasite	parasite	NOUN
cord-301856-71syce4n	55	73	,	,	PUNCT
cord-301856-71syce4n	55	74	relative	relative	ADJ
cord-301856-71syce4n	55	75	to	to	ADP
cord-301856-71syce4n	55	76	wild	wild	ADJ
cord-301856-71syce4n	55	77	type	type	NOUN
cord-301856-71syce4n	55	78	(	(	PUNCT
cord-301856-71syce4n	55	79	wt	wt	PROPN
cord-301856-71syce4n	55	80	)	)	PUNCT
cord-301856-71syce4n	55	81	infected	infected	ADJ
cord-301856-71syce4n	55	82	mice	mouse	NOUN
cord-301856-71syce4n	55	83	[	[	PUNCT
cord-301856-71syce4n	55	84	14	14	NUM
cord-301856-71syce4n	55	85	]	]	PUNCT
cord-301856-71syce4n	55	86	.	.	PUNCT
cord-301856-71syce4n	56	1	however	however	ADV
cord-301856-71syce4n	56	2	,	,	PUNCT
cord-301856-71syce4n	56	3	others	other	NOUN
cord-301856-71syce4n	56	4	have	have	AUX
cord-301856-71syce4n	56	5	questioned	question	VERB
cord-301856-71syce4n	56	6	these	these	DET
cord-301856-71syce4n	56	7	findings	finding	NOUN
cord-301856-71syce4n	56	8	,	,	PUNCT
cord-301856-71syce4n	56	9	given	give	VERB
cord-301856-71syce4n	56	10	that	that	SCONJ
cord-301856-71syce4n	56	11	caspase	caspase	NOUN
cord-301856-71syce4n	56	12	12	12	NUM
cord-301856-71syce4n	56	13	-	-	PUNCT
cord-301856-71syce4n	56	14	deficient	deficient	ADJ
cord-301856-71syce4n	56	15	mice	mouse	NOUN
cord-301856-71syce4n	56	16	also	also	ADV
cord-301856-71syce4n	56	17	lack	lack	VERB
cord-301856-71syce4n	56	18	caspase	caspase	NOUN
cord-301856-71syce4n	56	19	11	11	NUM
cord-301856-71syce4n	56	20	expression	expression	NOUN
cord-301856-71syce4n	56	21	,	,	PUNCT
cord-301856-71syce4n	56	22	so	so	SCONJ
cord-301856-71syce4n	56	23	the	the	DET
cord-301856-71syce4n	56	24	effects	effect	NOUN
cord-301856-71syce4n	56	25	observed	observe	VERB
cord-301856-71syce4n	56	26	might	might	AUX
cord-301856-71syce4n	56	27	not	not	PART
cord-301856-71syce4n	56	28	be	be	AUX
cord-301856-71syce4n	56	29	specific	specific	ADJ
cord-301856-71syce4n	56	30	to	to	ADP
cord-301856-71syce4n	56	31	caspase	caspase	NOUN
cord-301856-71syce4n	56	32	12	12	NUM
cord-301856-71syce4n	56	33	[	[	PUNCT
cord-301856-71syce4n	56	34	15	15	NUM
cord-301856-71syce4n	56	35	]	]	PUNCT
cord-301856-71syce4n	56	36	.	.	PUNCT
cord-301856-71syce4n	57	1	mycobacterium	mycobacterium	NOUN
cord-301856-71syce4n	57	2	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	57	3	(	(	PUNCT
cord-301856-71syce4n	57	4	mtb	mtb	X
cord-301856-71syce4n	57	5	)	)	PUNCT
cord-301856-71syce4n	57	6	has	have	AUX
cord-301856-71syce4n	57	7	caused	cause	VERB
cord-301856-71syce4n	57	8	infections	infection	NOUN
cord-301856-71syce4n	57	9	in	in	ADP
cord-301856-71syce4n	57	10	our	our	PRON
cord-301856-71syce4n	57	11	species	specie	NOUN
cord-301856-71syce4n	57	12	and	and	CCONJ
cord-301856-71syce4n	57	13	ancestors	ancestor	NOUN
cord-301856-71syce4n	57	14	for	for	ADP
cord-301856-71syce4n	57	15	at	at	ADV
cord-301856-71syce4n	57	16	least	least	ADV
cord-301856-71syce4n	57	17	500	500	NUM
cord-301856-71syce4n	57	18	000	000	NUM
cord-301856-71syce4n	57	19	years	year	NOUN
cord-301856-71syce4n	57	20	[	[	PUNCT
cord-301856-71syce4n	57	21	16	16	NUM
cord-301856-71syce4n	57	22	]	]	PUNCT
cord-301856-71syce4n	57	23	.	.	PUNCT
cord-301856-71syce4n	58	1	this	this	DET
cord-301856-71syce4n	58	2	long	long	ADV
cord-301856-71syce4n	58	3	-	-	PUNCT
cord-301856-71syce4n	58	4	standing	stand	VERB
cord-301856-71syce4n	58	5	relationship	relationship	NOUN
cord-301856-71syce4n	58	6	between	between	ADP
cord-301856-71syce4n	58	7	humans	human	NOUN
cord-301856-71syce4n	58	8	and	and	CCONJ
cord-301856-71syce4n	58	9	mtb	mtb	NOUN
cord-301856-71syce4n	58	10	probably	probably	ADV
cord-301856-71syce4n	58	11	underlies	underlie	VERB
cord-301856-71syce4n	58	12	the	the	DET
cord-301856-71syce4n	58	13	large	large	ADJ
cord-301856-71syce4n	58	14	variety	variety	NOUN
cord-301856-71syce4n	58	15	of	of	ADP
cord-301856-71syce4n	58	16	immune	immune	NOUN
cord-301856-71syce4n	58	17	-	-	PUNCT
cord-301856-71syce4n	58	18	related	relate	VERB
cord-301856-71syce4n	58	19	factors	factor	NOUN
cord-301856-71syce4n	58	20	that	that	PRON
cord-301856-71syce4n	58	21	modulate	modulate	VERB
cord-301856-71syce4n	58	22	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	58	23	to	to	ADP
cord-301856-71syce4n	58	24	mtb	mtb	NOUN
cord-301856-71syce4n	58	25	infection	infection	NOUN
cord-301856-71syce4n	58	26	,	,	PUNCT
cord-301856-71syce4n	58	27	including	include	VERB
cord-301856-71syce4n	58	28	vitamin	vitamin	NOUN
cord-301856-71syce4n	58	29	d	d	NOUN
cord-301856-71syce4n	58	30	receptor	receptor	NOUN
cord-301856-71syce4n	58	31	(	(	PUNCT
cord-301856-71syce4n	58	32	vdr	vdr	NOUN
cord-301856-71syce4n	58	33	)	)	PUNCT
cord-301856-71syce4n	58	34	,	,	PUNCT
cord-301856-71syce4n	58	35	natural	natural	ADJ
cord-301856-71syce4n	58	36	resistance	resistance	NOUN
cord-301856-71syce4n	58	37	-	-	PUNCT
cord-301856-71syce4n	58	38	associated	associate	VERB
cord-301856-71syce4n	58	39	macrophage	macrophage	NOUN
cord-301856-71syce4n	58	40	protein	protein	NOUN
cord-301856-71syce4n	58	41	1	1	NUM
cord-301856-71syce4n	58	42	(	(	PUNCT
cord-301856-71syce4n	58	43	slc11a1	slc11a1	PROPN
cord-301856-71syce4n	58	44	)	)	PUNCT
cord-301856-71syce4n	58	45	,	,	PUNCT
cord-301856-71syce4n	58	46	tir	tir	X
cord-301856-71syce4n	58	47	domain	domain	NOUN
cord-301856-71syce4n	58	48	containing	contain	VERB
cord-301856-71syce4n	58	49	adaptor	adaptor	NOUN
cord-301856-71syce4n	58	50	protein	protein	NOUN
cord-301856-71syce4n	58	51	(	(	PUNCT
cord-301856-71syce4n	58	52	tirap	tirap	PROPN
cord-301856-71syce4n	58	53	)	)	PUNCT
cord-301856-71syce4n	58	54	,	,	PUNCT
cord-301856-71syce4n	58	55	hla	hla	PROPN
cord-301856-71syce4n	58	56	,	,	PUNCT
cord-301856-71syce4n	58	57	monocyte	monocyte	NOUN
cord-301856-71syce4n	58	58	chemoattractant	chemoattractant	NOUN
cord-301856-71syce4n	58	59	protein	protein	NOUN
cord-301856-71syce4n	58	60	1	1	NUM
cord-301856-71syce4n	58	61	(	(	PUNCT
cord-301856-71syce4n	58	62	mcp-1	mcp-1	SYM
cord-301856-71syce4n	58	63	)	)	PUNCT
cord-301856-71syce4n	58	64	,	,	PUNCT
cord-301856-71syce4n	58	65	and	and	CCONJ
cord-301856-71syce4n	58	66	cytokines	cytokine	NOUN
cord-301856-71syce4n	58	67	such	such	ADJ
cord-301856-71syce4n	58	68	as	as	ADP
cord-301856-71syce4n	58	69	il-12	il-12	NOUN
cord-301856-71syce4n	58	70	and	and	CCONJ
cord-301856-71syce4n	58	71	ifn	ifn	NOUN
cord-301856-71syce4n	58	72	-	-	PUNCT
cord-301856-71syce4n	58	73	g	g	NOUN
cord-301856-71syce4n	59	1	[	[	PUNCT
cord-301856-71syce4n	59	2	17	17	NUM
cord-301856-71syce4n	59	3	]	]	PUNCT
cord-301856-71syce4n	59	4	(	(	PUNCT
cord-301856-71syce4n	59	5	table	table	NOUN
cord-301856-71syce4n	59	6	1	1	NUM
cord-301856-71syce4n	59	7	)	)	PUNCT
cord-301856-71syce4n	59	8	.	.	PUNCT
cord-301856-71syce4n	60	1	patients	patient	NOUN
cord-301856-71syce4n	60	2	with	with	ADP
cord-301856-71syce4n	60	3	african	african	ADJ
cord-301856-71syce4n	60	4	ancestry	ancestry	PROPN
cord-301856-71syce4n	60	5	present	present	VERB
cord-301856-71syce4n	60	6	a	a	DET
cord-301856-71syce4n	60	7	higher	high	ADJ
cord-301856-71syce4n	60	8	frequency	frequency	NOUN
cord-301856-71syce4n	60	9	of	of	ADP
cord-301856-71syce4n	60	10	mtb	mtb	NOUN
cord-301856-71syce4n	60	11	-	-	PUNCT
cord-301856-71syce4n	60	12	related	relate	VERB
cord-301856-71syce4n	60	13	genetic	genetic	ADJ
cord-301856-71syce4n	60	14	variants	variant	NOUN
cord-301856-71syce4n	60	15	than	than	ADP
cord-301856-71syce4n	60	16	individuals	individual	NOUN
cord-301856-71syce4n	60	17	from	from	ADP
cord-301856-71syce4n	60	18	other	other	ADJ
cord-301856-71syce4n	60	19	populations	population	NOUN
cord-301856-71syce4n	60	20	,	,	PUNCT
cord-301856-71syce4n	60	21	including	include	VERB
cord-301856-71syce4n	60	22	variants	variant	NOUN
cord-301856-71syce4n	60	23	in	in	ADP
cord-301856-71syce4n	60	24	the	the	DET
cord-301856-71syce4n	60	25	gene	gene	NOUN
cord-301856-71syce4n	60	26	encoding	encode	VERB
cord-301856-71syce4n	60	27	for	for	ADP
cord-301856-71syce4n	60	28	toll	toll	NOUN
cord-301856-71syce4n	60	29	-	-	PUNCT
cord-301856-71syce4n	60	30	like	like	ADJ
cord-301856-71syce4n	60	31	receptor	receptor	NOUN
cord-301856-71syce4n	60	32	6	6	NUM
cord-301856-71syce4n	60	33	(	(	PUNCT
cord-301856-71syce4n	60	34	tlr6	tlr6	PROPN
cord-301856-71syce4n	60	35	)	)	PUNCT
cord-301856-71syce4n	60	36	,	,	PUNCT
cord-301856-71syce4n	60	37	mediating	mediate	VERB
cord-301856-71syce4n	60	38	cellular	cellular	ADJ
cord-301856-71syce4n	60	39	responses	response	NOUN
cord-301856-71syce4n	60	40	to	to	ADP
cord-301856-71syce4n	60	41	bacterial	bacterial	ADJ
cord-301856-71syce4n	60	42	malaria	malaria	NOUN
cord-301856-71syce4n	60	43	is	be	AUX
cord-301856-71syce4n	60	44	one	one	NUM
cord-301856-71syce4n	60	45	of	of	ADP
cord-301856-71syce4n	60	46	the	the	DET
cord-301856-71syce4n	60	47	greatest	great	ADJ
cord-301856-71syce4n	60	48	causes	cause	NOUN
cord-301856-71syce4n	60	49	of	of	ADP
cord-301856-71syce4n	60	50	morbidity	morbidity	NOUN
cord-301856-71syce4n	60	51	and	and	CCONJ
cord-301856-71syce4n	60	52	mortality	mortality	NOUN
cord-301856-71syce4n	60	53	in	in	ADP
cord-301856-71syce4n	60	54	the	the	DET
cord-301856-71syce4n	60	55	history	history	NOUN
cord-301856-71syce4n	60	56	of	of	ADP
cord-301856-71syce4n	60	57	humanity	humanity	NOUN
cord-301856-71syce4n	60	58	.	.	PUNCT
cord-301856-71syce4n	61	1	most	most	ADJ
cord-301856-71syce4n	61	2	human	human	ADJ
cord-301856-71syce4n	61	3	populations	population	NOUN
cord-301856-71syce4n	61	4	with	with	ADP
cord-301856-71syce4n	61	5	a	a	DET
cord-301856-71syce4n	61	6	long	long	ADJ
cord-301856-71syce4n	61	7	history	history	NOUN
cord-301856-71syce4n	61	8	of	of	ADP
cord-301856-71syce4n	61	9	endemic	endemic	ADJ
cord-301856-71syce4n	61	10	malaria	malaria	NOUN
cord-301856-71syce4n	61	11	have	have	AUX
cord-301856-71syce4n	61	12	evolved	evolve	VERB
cord-301856-71syce4n	61	13	genetic	genetic	ADJ
cord-301856-71syce4n	61	14	adaptations	adaptation	NOUN
cord-301856-71syce4n	61	15	to	to	ADP
cord-301856-71syce4n	61	16	malaria	malaria	NOUN
cord-301856-71syce4n	61	17	parasites	parasite	NOUN
cord-301856-71syce4n	61	18	due	due	ADP
cord-301856-71syce4n	61	19	to	to	ADP
cord-301856-71syce4n	61	20	the	the	DET
cord-301856-71syce4n	61	21	strong	strong	ADJ
cord-301856-71syce4n	61	22	selective	selective	ADJ
cord-301856-71syce4n	61	23	pressure	pressure	NOUN
cord-301856-71syce4n	61	24	that	that	SCONJ
cord-301856-71syce4n	61	25	this	this	DET
cord-301856-71syce4n	61	26	infection	infection	NOUN
cord-301856-71syce4n	61	27	has	have	AUX
cord-301856-71syce4n	61	28	exerted	exert	VERB
cord-301856-71syce4n	61	29	.	.	PUNCT
cord-301856-71syce4n	62	1	since	since	SCONJ
cord-301856-71syce4n	62	2	the	the	DET
cord-301856-71syce4n	62	3	parasite	parasite	NOUN
cord-301856-71syce4n	62	4	infects	infect	VERB
cord-301856-71syce4n	62	5	erythrocytes	erythrocyte	NOUN
cord-301856-71syce4n	62	6	,	,	PUNCT
cord-301856-71syce4n	62	7	the	the	DET
cord-301856-71syce4n	62	8	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	62	9	pressure	pressure	NOUN
cord-301856-71syce4n	62	10	has	have	AUX
cord-301856-71syce4n	62	11	selected	select	VERB
cord-301856-71syce4n	62	12	genetic	genetic	ADJ
cord-301856-71syce4n	62	13	variants	variant	NOUN
cord-301856-71syce4n	62	14	that	that	PRON
cord-301856-71syce4n	62	15	affect	affect	VERB
cord-301856-71syce4n	62	16	red	red	ADJ
cord-301856-71syce4n	62	17	blood	blood	NOUN
cord-301856-71syce4n	62	18	cells	cell	NOUN
cord-301856-71syce4n	62	19	and	and	CCONJ
cord-301856-71syce4n	62	20	,	,	PUNCT
cord-301856-71syce4n	62	21	therefore	therefore	ADV
cord-301856-71syce4n	62	22	,	,	PUNCT
cord-301856-71syce4n	62	23	the	the	DET
cord-301856-71syce4n	62	24	survival	survival	NOUN
cord-301856-71syce4n	62	25	of	of	ADP
cord-301856-71syce4n	62	26	the	the	DET
cord-301856-71syce4n	62	27	parasite	parasite	NOUN
cord-301856-71syce4n	62	28	as	as	ADV
cord-301856-71syce4n	62	29	well	well	ADV
cord-301856-71syce4n	62	30	.	.	PUNCT
cord-301856-71syce4n	63	1	genetic	genetic	ADJ
cord-301856-71syce4n	63	2	variants	variant	NOUN
cord-301856-71syce4n	63	3	conferring	confer	VERB
cord-301856-71syce4n	63	4	resistance	resistance	NOUN
cord-301856-71syce4n	63	5	to	to	ADP
cord-301856-71syce4n	63	6	the	the	DET
cord-301856-71syce4n	63	7	disease	disease	NOUN
cord-301856-71syce4n	63	8	have	have	AUX
cord-301856-71syce4n	63	9	spread	spread	VERB
cord-301856-71syce4n	63	10	through	through	ADP
cord-301856-71syce4n	63	11	human	human	ADJ
cord-301856-71syce4n	63	12	populations	population	NOUN
cord-301856-71syce4n	63	13	over	over	ADP
cord-301856-71syce4n	63	14	time	time	NOUN
cord-301856-71syce4n	63	15	,	,	PUNCT
cord-301856-71syce4n	63	16	including	include	VERB
cord-301856-71syce4n	63	17	several	several	ADJ
cord-301856-71syce4n	63	18	abnormal	abnormal	ADJ
cord-301856-71syce4n	63	19	hemoglobins	hemoglobin	NOUN
cord-301856-71syce4n	63	20	that	that	PRON
cord-301856-71syce4n	63	21	protect	protect	VERB
cord-301856-71syce4n	63	22	against	against	ADP
cord-301856-71syce4n	63	23	malaria	malaria	NOUN
cord-301856-71syce4n	63	24	but	but	CCONJ
cord-301856-71syce4n	63	25	usually	usually	ADV
cord-301856-71syce4n	63	26	cause	cause	VERB
cord-301856-71syce4n	63	27	erythrocyte	erythrocyte	NOUN
cord-301856-71syce4n	63	28	-	-	PUNCT
cord-301856-71syce4n	63	29	associated	associate	VERB
cord-301856-71syce4n	63	30	diseases	disease	NOUN
cord-301856-71syce4n	63	31	in	in	ADP
cord-301856-71syce4n	63	32	the	the	DET
cord-301856-71syce4n	63	33	populations	population	NOUN
cord-301856-71syce4n	63	34	where	where	SCONJ
cord-301856-71syce4n	63	35	these	these	DET
cord-301856-71syce4n	63	36	adaptations	adaptation	NOUN
cord-301856-71syce4n	63	37	are	be	AUX
cord-301856-71syce4n	63	38	prevalent	prevalent	ADJ
cord-301856-71syce4n	63	39	.	.	PUNCT
cord-301856-71syce4n	64	1	these	these	DET
cord-301856-71syce4n	64	2	factors	factor	NOUN
cord-301856-71syce4n	64	3	include	include	VERB
cord-301856-71syce4n	64	4	the	the	DET
cord-301856-71syce4n	64	5	t	t	PROPN
cord-301856-71syce4n	64	6	125	125	NUM
cord-301856-71syce4n	64	7	c	c	NOUN
cord-301856-71syce4n	64	8	polymorphism	polymorphism	NOUN
cord-301856-71syce4n	64	9	in	in	ADP
cord-301856-71syce4n	64	10	the	the	DET
cord-301856-71syce4n	64	11	caspase	caspase	NOUN
cord-301856-71syce4n	64	12	12	12	NUM
cord-301856-71syce4n	64	13	gene	gene	NOUN
cord-301856-71syce4n	64	14	(	(	PUNCT
cord-301856-71syce4n	64	15	casp12	casp12	NOUN
cord-301856-71syce4n	64	16	)	)	PUNCT
cord-301856-71syce4n	64	17	;	;	PUNCT
cord-301856-71syce4n	64	18	the	the	DET
cord-301856-71syce4n	64	19	hemoglobin	hemoglobin	PROPN
cord-301856-71syce4n	64	20	b	b	PROPN
cord-301856-71syce4n	64	21	(	(	PUNCT
cord-301856-71syce4n	64	22	hbb	hbb	PROPN
cord-301856-71syce4n	64	23	)	)	PUNCT
cord-301856-71syce4n	64	24	and	and	CCONJ
cord-301856-71syce4n	64	25	hemoglobin	hemoglobin	PROPN
cord-301856-71syce4n	64	26	c	c	PROPN
cord-301856-71syce4n	64	27	(	(	PUNCT
cord-301856-71syce4n	64	28	hbc	hbc	PROPN
cord-301856-71syce4n	64	29	)	)	PUNCT
cord-301856-71syce4n	64	30	variants	variant	NOUN
cord-301856-71syce4n	64	31	;	;	PUNCT
cord-301856-71syce4n	64	32	mutations	mutation	NOUN
cord-301856-71syce4n	64	33	in	in	ADP
cord-301856-71syce4n	64	34	the	the	DET
cord-301856-71syce4n	64	35	duffy	duffy	ADJ
cord-301856-71syce4n	64	36	antigen	antigen	PROPN
cord-301856-71syce4n	64	37	receptor	receptor	NOUN
cord-301856-71syce4n	64	38	gene	gene	NOUN
cord-301856-71syce4n	64	39	(	(	PUNCT
cord-301856-71syce4n	64	40	darc	darc	PROPN
cord-301856-71syce4n	64	41	)	)	PUNCT
cord-301856-71syce4n	64	42	;	;	PUNCT
cord-301856-71syce4n	64	43	thalassemias	thalassemia	NOUN
cord-301856-71syce4n	64	44	(	(	PUNCT
cord-301856-71syce4n	64	45	a	a	PROPN
cord-301856-71syce4n	64	46	and	and	CCONJ
cord-301856-71syce4n	64	47	b	b	NUM
cord-301856-71syce4n	64	48	)	)	PUNCT
cord-301856-71syce4n	64	49	;	;	PUNCT
cord-301856-71syce4n	64	50	sickle	sickle	ADJ
cord-301856-71syce4n	64	51	cell	cell	NOUN
cord-301856-71syce4n	64	52	disease	disease	NOUN
cord-301856-71syce4n	64	53	;	;	PUNCT
cord-301856-71syce4n	64	54	and	and	CCONJ
cord-301856-71syce4n	64	55	polymorphisms	polymorphism	NOUN
cord-301856-71syce4n	64	56	in	in	ADP
cord-301856-71syce4n	64	57	the	the	DET
cord-301856-71syce4n	64	58	human	human	ADJ
cord-301856-71syce4n	64	59	leukocyte	leukocyte	NOUN
cord-301856-71syce4n	64	60	antigen	antigen	PROPN
cord-301856-71syce4n	64	61	(	(	PUNCT
cord-301856-71syce4n	64	62	hla	hla	PROPN
cord-301856-71syce4n	64	63	)	)	PUNCT
cord-301856-71syce4n	64	64	loci	loci	NOUN
cord-301856-71syce4n	64	65	.	.	PUNCT
cord-301856-71syce4n	65	1	dna	dna	PROPN
cord-301856-71syce4n	65	2	nucleotide	nucleotide	NOUN
cord-301856-71syce4n	65	3	.	.	PUNCT
cord-301856-71syce4n	66	1	for	for	ADP
cord-301856-71syce4n	66	2	example	example	NOUN
cord-301856-71syce4n	66	3	,	,	PUNCT
cord-301856-71syce4n	66	4	an	an	DET
cord-301856-71syce4n	66	5	snp	snp	PROPN
cord-301856-71syce4n	66	6	may	may	AUX
cord-301856-71syce4n	66	7	replace	replace	VERB
cord-301856-71syce4n	66	8	cytosine	cytosine	NOUN
cord-301856-71syce4n	66	9	(	(	PUNCT
cord-301856-71syce4n	66	10	c	c	NOUN
cord-301856-71syce4n	66	11	)	)	PUNCT
cord-301856-71syce4n	66	12	with	with	ADP
cord-301856-71syce4n	66	13	thymine	thymine	NOUN
cord-301856-71syce4n	66	14	(	(	PUNCT
cord-301856-71syce4n	66	15	t	t	NOUN
cord-301856-71syce4n	66	16	)	)	PUNCT
cord-301856-71syce4n	66	17	in	in	ADP
cord-301856-71syce4n	66	18	a	a	DET
cord-301856-71syce4n	66	19	certain	certain	ADJ
cord-301856-71syce4n	66	20	segment	segment	NOUN
cord-301856-71syce4n	66	21	of	of	ADP
cord-301856-71syce4n	66	22	dna	dna	PROPN
cord-301856-71syce4n	66	23	.	.	PUNCT
cord-301856-71syce4n	67	1	selective	selective	ADJ
cord-301856-71syce4n	67	2	pressure	pressure	NOUN
cord-301856-71syce4n	67	3	:	:	PUNCT
cord-301856-71syce4n	67	4	phenomenon	phenomenon	NOUN
cord-301856-71syce4n	67	5	that	that	PRON
cord-301856-71syce4n	67	6	alters	alter	VERB
cord-301856-71syce4n	67	7	the	the	DET
cord-301856-71syce4n	67	8	behavior	behavior	NOUN
cord-301856-71syce4n	67	9	and	and	CCONJ
cord-301856-71syce4n	67	10	fitness	fitness	NOUN
cord-301856-71syce4n	67	11	of	of	ADP
cord-301856-71syce4n	67	12	living	live	VERB
cord-301856-71syce4n	67	13	organisms	organism	NOUN
cord-301856-71syce4n	67	14	within	within	ADP
cord-301856-71syce4n	67	15	a	a	DET
cord-301856-71syce4n	67	16	given	give	VERB
cord-301856-71syce4n	67	17	environment	environment	NOUN
cord-301856-71syce4n	67	18	.	.	PUNCT
cord-301856-71syce4n	68	1	it	it	PRON
cord-301856-71syce4n	68	2	is	be	AUX
cord-301856-71syce4n	68	3	the	the	DET
cord-301856-71syce4n	68	4	driving	drive	VERB
cord-301856-71syce4n	68	5	force	force	NOUN
cord-301856-71syce4n	68	6	of	of	ADP
cord-301856-71syce4n	68	7	evolution	evolution	NOUN
cord-301856-71syce4n	68	8	and	and	CCONJ
cord-301856-71syce4n	68	9	natural	natural	ADJ
cord-301856-71syce4n	68	10	selection	selection	NOUN
cord-301856-71syce4n	68	11	.	.	PUNCT
cord-301856-71syce4n	69	1	thalassemias	thalassemia	NOUN
cord-301856-71syce4n	69	2	(	(	PUNCT
cord-301856-71syce4n	69	3	a	a	NOUN
cord-301856-71syce4n	69	4	and	and	CCONJ
cord-301856-71syce4n	69	5	b	b	PROPN
cord-301856-71syce4n	69	6	):	):	PUNCT
cord-301856-71syce4n	69	7	inherited	inherit	VERB
cord-301856-71syce4n	69	8	hemoglobinopathies	hemoglobinopathy	NOUN
cord-301856-71syce4n	69	9	characterized	characterize	VERB
cord-301856-71syce4n	69	10	by	by	ADP
cord-301856-71syce4n	69	11	a	a	DET
cord-301856-71syce4n	69	12	failure	failure	NOUN
cord-301856-71syce4n	69	13	in	in	ADP
cord-301856-71syce4n	69	14	the	the	DET
cord-301856-71syce4n	69	15	synthesis	synthesis	NOUN
cord-301856-71syce4n	69	16	of	of	ADP
cord-301856-71syce4n	69	17	the	the	DET
cord-301856-71syce4n	69	18	globin	globin	PROPN
cord-301856-71syce4n	69	19	alpha	alpha	NOUN
cord-301856-71syce4n	69	20	or	or	CCONJ
cord-301856-71syce4n	69	21	beta	beta	ADJ
cord-301856-71syce4n	69	22	chains	chain	NOUN
cord-301856-71syce4n	69	23	.	.	PUNCT
cord-301856-71syce4n	70	1	toll	toll	NOUN
cord-301856-71syce4n	70	2	-	-	PUNCT
cord-301856-71syce4n	70	3	like	like	ADJ
cord-301856-71syce4n	70	4	receptors	receptor	NOUN
cord-301856-71syce4n	70	5	:	:	PUNCT
cord-301856-71syce4n	70	6	family	family	NOUN
cord-301856-71syce4n	70	7	of	of	ADP
cord-301856-71syce4n	70	8	transmembrane	transmembrane	NOUN
cord-301856-71syce4n	70	9	pattern	pattern	NOUN
cord-301856-71syce4n	70	10	recognition	recognition	NOUN
cord-301856-71syce4n	70	11	receptors	receptor	NOUN
cord-301856-71syce4n	70	12	expressed	express	VERB
cord-301856-71syce4n	70	13	by	by	ADP
cord-301856-71syce4n	70	14	immune	immune	ADJ
cord-301856-71syce4n	70	15	and	and	CCONJ
cord-301856-71syce4n	70	16	nonimmune	nonimmune	ADJ
cord-301856-71syce4n	70	17	cells	cell	NOUN
cord-301856-71syce4n	70	18	that	that	PRON
cord-301856-71syce4n	70	19	recognize	recognize	VERB
cord-301856-71syce4n	70	20	conserved	conserved	ADJ
cord-301856-71syce4n	70	21	pathogenassociated	pathogenassociated	ADJ
cord-301856-71syce4n	70	22	molecular	molecular	ADJ
cord-301856-71syce4n	70	23	patterns	pattern	NOUN
cord-301856-71syce4n	70	24	.	.	PUNCT
cord-301856-71syce4n	71	1	they	they	PRON
cord-301856-71syce4n	71	2	play	play	VERB
cord-301856-71syce4n	71	3	a	a	DET
cord-301856-71syce4n	71	4	pivotal	pivotal	ADJ
cord-301856-71syce4n	71	5	role	role	NOUN
cord-301856-71syce4n	71	6	in	in	ADP
cord-301856-71syce4n	71	7	innate	innate	ADJ
cord-301856-71syce4n	71	8	immunity	immunity	NOUN
cord-301856-71syce4n	71	9	.	.	PUNCT
cord-301856-71syce4n	72	1	transgenerational	transgenerational	ADJ
cord-301856-71syce4n	72	2	inheritance	inheritance	NOUN
cord-301856-71syce4n	72	3	:	:	PUNCT
cord-301856-71syce4n	72	4	transmission	transmission	NOUN
cord-301856-71syce4n	72	5	of	of	ADP
cord-301856-71syce4n	72	6	traits	trait	NOUN
cord-301856-71syce4n	72	7	from	from	ADP
cord-301856-71syce4n	72	8	generation	generation	NOUN
cord-301856-71syce4n	72	9	to	to	ADP
cord-301856-71syce4n	72	10	generation	generation	NOUN
cord-301856-71syce4n	72	11	.	.	PUNCT
cord-301856-71syce4n	73	1	trends	trend	NOUN
cord-301856-71syce4n	73	2	in	in	ADP
cord-301856-71syce4n	73	3	immunology	immunology	NOUN
cord-301856-71syce4n	73	4	,	,	PUNCT
cord-301856-71syce4n	73	5	december	december	PROPN
cord-301856-71syce4n	73	6	2019	2019	NUM
cord-301856-71syce4n	73	7	,	,	PUNCT
cord-301856-71syce4n	73	8	vol	vol	PROPN
cord-301856-71syce4n	73	9	.	.	PROPN
cord-301856-71syce4n	73	10	40	40	NUM
cord-301856-71syce4n	73	11	,	,	PUNCT
cord-301856-71syce4n	73	12	no	no	NOUN
cord-301856-71syce4n	73	13	.	.	NOUN
cord-301856-71syce4n	73	14	12	12	NUM
cord-301856-71syce4n	73	15	1107	1107	NUM
cord-301856-71syce4n	73	16	lipoproteins	lipoprotein	NOUN
cord-301856-71syce4n	73	17	[	[	PUNCT
cord-301856-71syce4n	73	18	18	18	NUM
cord-301856-71syce4n	73	19	,	,	PUNCT
cord-301856-71syce4n	73	20	19	19	NUM
cord-301856-71syce4n	73	21	]	]	PUNCT
cord-301856-71syce4n	73	22	.	.	PUNCT
cord-301856-71syce4n	74	1	selective	selective	ADJ
cord-301856-71syce4n	74	2	pressure	pressure	NOUN
cord-301856-71syce4n	74	3	has	have	AUX
cord-301856-71syce4n	74	4	also	also	ADV
cord-301856-71syce4n	74	5	shaped	shape	VERB
cord-301856-71syce4n	74	6	the	the	DET
cord-301856-71syce4n	74	7	mechanisms	mechanism	NOUN
cord-301856-71syce4n	74	8	that	that	PRON
cord-301856-71syce4n	74	9	modulate	modulate	VERB
cord-301856-71syce4n	74	10	the	the	DET
cord-301856-71syce4n	74	11	expression	expression	NOUN
cord-301856-71syce4n	74	12	of	of	ADP
cord-301856-71syce4n	74	13	genes	gene	NOUN
cord-301856-71syce4n	74	14	implicated	implicate	VERB
cord-301856-71syce4n	74	15	in	in	ADP
cord-301856-71syce4n	74	16	immune	immune	ADJ
cord-301856-71syce4n	74	17	responses	response	NOUN
cord-301856-71syce4n	74	18	against	against	ADP
cord-301856-71syce4n	74	19	lassa	lassa	ADJ
cord-301856-71syce4n	74	20	virus	virus	NOUN
cord-301856-71syce4n	74	21	,	,	PUNCT
cord-301856-71syce4n	74	22	such	such	ADJ
cord-301856-71syce4n	74	23	as	as	ADP
cord-301856-71syce4n	74	24	il-21	il-21	NOUN
cord-301856-71syce4n	74	25	(	(	PUNCT
cord-301856-71syce4n	74	26	il21	il21	PROPN
cord-301856-71syce4n	74	27	)	)	PUNCT
cord-301856-71syce4n	74	28	and	and	CCONJ
cord-301856-71syce4n	74	29	the	the	DET
cord-301856-71syce4n	74	30	glycosyltransferase	glycosyltransferase	NOUN
cord-301856-71syce4n	74	31	-	-	PUNCT
cord-301856-71syce4n	74	32	like	like	ADJ
cord-301856-71syce4n	74	33	protein	protein	NOUN
cord-301856-71syce4n	74	34	large1	large1	ADJ
cord-301856-71syce4n	74	35	(	(	PUNCT
cord-301856-71syce4n	74	36	large	large	ADJ
cord-301856-71syce4n	74	37	)	)	PUNCT
cord-301856-71syce4n	74	38	,	,	PUNCT
cord-301856-71syce4n	74	39	suggesting	suggest	VERB
cord-301856-71syce4n	74	40	that	that	SCONJ
cord-301856-71syce4n	74	41	the	the	DET
cord-301856-71syce4n	74	42	natural	natural	ADJ
cord-301856-71syce4n	74	43	selection	selection	NOUN
cord-301856-71syce4n	74	44	exerted	exert	VERB
cord-301856-71syce4n	74	45	by	by	ADP
cord-301856-71syce4n	74	46	the	the	DET
cord-301856-71syce4n	74	47	virus	virus	NOUN
cord-301856-71syce4n	74	48	drove	drive	VERB
cord-301856-71syce4n	74	49	the	the	DET
cord-301856-71syce4n	74	50	expansion	expansion	NOUN
cord-301856-71syce4n	74	51	of	of	ADP
cord-301856-71syce4n	74	52	genetic	genetic	ADJ
cord-301856-71syce4n	74	53	variants	variant	NOUN
cord-301856-71syce4n	74	54	that	that	PRON
cord-301856-71syce4n	74	55	enhance	enhance	VERB
cord-301856-71syce4n	74	56	immunity	immunity	NOUN
cord-301856-71syce4n	74	57	against	against	ADP
cord-301856-71syce4n	74	58	lassa	lassa	ADJ
cord-301856-71syce4n	74	59	fever	fever	NOUN
cord-301856-71syce4n	74	60	[	[	PUNCT
cord-301856-71syce4n	74	61	20	20	NUM
cord-301856-71syce4n	74	62	]	]	PUNCT
cord-301856-71syce4n	74	63	.	.	PUNCT
cord-301856-71syce4n	75	1	these	these	DET
cord-301856-71syce4n	75	2	examples	example	NOUN
cord-301856-71syce4n	75	3	indicate	indicate	VERB
cord-301856-71syce4n	75	4	that	that	SCONJ
cord-301856-71syce4n	75	5	infectious	infectious	ADJ
cord-301856-71syce4n	75	6	diseases	disease	NOUN
cord-301856-71syce4n	75	7	have	have	AUX
cord-301856-71syce4n	75	8	contributed	contribute	VERB
cord-301856-71syce4n	75	9	to	to	ADP
cord-301856-71syce4n	75	10	shaping	shape	VERB
cord-301856-71syce4n	75	11	the	the	DET
cord-301856-71syce4n	75	12	genetic	genetic	ADJ
cord-301856-71syce4n	75	13	landscape	landscape	NOUN
cord-301856-71syce4n	75	14	of	of	ADP
cord-301856-71syce4n	75	15	african	african	ADJ
cord-301856-71syce4n	75	16	populations	population	NOUN
cord-301856-71syce4n	75	17	and	and	CCONJ
cord-301856-71syce4n	75	18	their	their	PRON
cord-301856-71syce4n	75	19	descendants	descendant	NOUN
cord-301856-71syce4n	75	20	,	,	PUNCT
cord-301856-71syce4n	75	21	and	and	CCONJ
cord-301856-71syce4n	75	22	highlight	highlight	VERB
cord-301856-71syce4n	75	23	the	the	DET
cord-301856-71syce4n	75	24	great	great	ADJ
cord-301856-71syce4n	75	25	impact	impact	NOUN
cord-301856-71syce4n	75	26	of	of	ADP
cord-301856-71syce4n	75	27	pathogens	pathogen	NOUN
cord-301856-71syce4n	75	28	as	as	ADP
cord-301856-71syce4n	75	29	an	an	DET
cord-301856-71syce4n	75	30	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	75	31	force	force	NOUN
cord-301856-71syce4n	75	32	in	in	ADP
cord-301856-71syce4n	75	33	humans	human	NOUN
cord-301856-71syce4n	75	34	.	.	PUNCT
cord-301856-71syce4n	76	1	our	our	PRON
cord-301856-71syce4n	76	2	homo	homo	PROPN
cord-301856-71syce4n	76	3	sapiens	sapiens	PROPN
cord-301856-71syce4n	76	4	ancestors	ancestor	NOUN
cord-301856-71syce4n	76	5	were	be	AUX
cord-301856-71syce4n	76	6	not	not	PART
cord-301856-71syce4n	76	7	the	the	DET
cord-301856-71syce4n	76	8	only	only	ADJ
cord-301856-71syce4n	76	9	species	specie	NOUN
cord-301856-71syce4n	76	10	to	to	PART
cord-301856-71syce4n	76	11	venture	venture	VERB
cord-301856-71syce4n	76	12	out	out	ADP
cord-301856-71syce4n	76	13	of	of	ADP
cord-301856-71syce4n	76	14	africa	africa	PROPN
cord-301856-71syce4n	76	15	,	,	PUNCT
cord-301856-71syce4n	76	16	with	with	ADP
cord-301856-71syce4n	76	17	other	other	ADJ
cord-301856-71syce4n	76	18	homo	homo	ADJ
cord-301856-71syce4n	76	19	species	specie	NOUN
cord-301856-71syce4n	76	20	performing	perform	VERB
cord-301856-71syce4n	76	21	a	a	DET
cord-301856-71syce4n	76	22	similar	similar	ADJ
cord-301856-71syce4n	76	23	migration	migration	NOUN
cord-301856-71syce4n	76	24	much	much	ADV
cord-301856-71syce4n	76	25	earlier	early	ADV
cord-301856-71syce4n	76	26	,	,	PUNCT
cord-301856-71syce4n	76	27	such	such	ADJ
cord-301856-71syce4n	76	28	as	as	ADP
cord-301856-71syce4n	76	29	homo	homo	ADJ
cord-301856-71syce4n	76	30	ergaster	ergaster	NOUN
cord-301856-71syce4n	76	31	,	,	PUNCT
cord-301856-71syce4n	76	32	homo	homo	ADJ
cord-301856-71syce4n	76	33	erectus	erectus	PROPN
cord-301856-71syce4n	76	34	,	,	PUNCT
cord-301856-71syce4n	76	35	or	or	CCONJ
cord-301856-71syce4n	76	36	homo	homo	ADJ
cord-301856-71syce4n	76	37	heidelbergensis	heidelbergensis	NOUN
cord-301856-71syce4n	76	38	[	[	PUNCT
cord-301856-71syce4n	76	39	21	21	NUM
cord-301856-71syce4n	76	40	]	]	PUNCT
cord-301856-71syce4n	76	41	.	.	PUNCT
cord-301856-71syce4n	77	1	from	from	ADP
cord-301856-71syce4n	77	2	these	these	DET
cord-301856-71syce4n	77	3	early	early	ADJ
cord-301856-71syce4n	77	4	migrations	migration	NOUN
cord-301856-71syce4n	77	5	,	,	PUNCT
cord-301856-71syce4n	77	6	local	local	ADJ
cord-301856-71syce4n	77	7	populations	population	NOUN
cord-301856-71syce4n	77	8	such	such	ADJ
cord-301856-71syce4n	77	9	as	as	ADP
cord-301856-71syce4n	77	10	the	the	DET
cord-301856-71syce4n	77	11	denisovans	denisovan	NOUN
cord-301856-71syce4n	77	12	and	and	CCONJ
cord-301856-71syce4n	77	13	neanderthals	neanderthal	NOUN
cord-301856-71syce4n	77	14	evolved	evolve	VERB
cord-301856-71syce4n	77	15	[	[	X
cord-301856-71syce4n	77	16	22	22	NUM
cord-301856-71syce4n	77	17	]	]	PUNCT
cord-301856-71syce4n	77	18	.	.	PUNCT
cord-301856-71syce4n	78	1	these	these	DET
cord-301856-71syce4n	78	2	lineages	lineage	NOUN
cord-301856-71syce4n	78	3	were	be	AUX
cord-301856-71syce4n	78	4	not	not	PART
cord-301856-71syce4n	78	5	geographically	geographically	ADV
cord-301856-71syce4n	78	6	isolated	isolate	VERB
cord-301856-71syce4n	78	7	,	,	PUNCT
cord-301856-71syce4n	78	8	but	but	CCONJ
cord-301856-71syce4n	78	9	lived	live	VERB
cord-301856-71syce4n	78	10	side	side	NOUN
cord-301856-71syce4n	78	11	by	by	ADP
cord-301856-71syce4n	78	12	side	side	NOUN
cord-301856-71syce4n	78	13	with	with	ADP
cord-301856-71syce4n	78	14	modern	modern	ADJ
cord-301856-71syce4n	78	15	humans	human	NOUN
cord-301856-71syce4n	78	16	and	and	CCONJ
cord-301856-71syce4n	78	17	interbred	interbreed	VERB
cord-301856-71syce4n	78	18	with	with	ADP
cord-301856-71syce4n	78	19	them	they	PRON
cord-301856-71syce4n	78	20	,	,	PUNCT
cord-301856-71syce4n	78	21	leaving	leave	VERB
cord-301856-71syce4n	78	22	a	a	DET
cord-301856-71syce4n	78	23	genetic	genetic	ADJ
cord-301856-71syce4n	78	24	footprint	footprint	NOUN
cord-301856-71syce4n	78	25	in	in	ADP
cord-301856-71syce4n	78	26	their	their	PRON
cord-301856-71syce4n	78	27	common	common	ADJ
cord-301856-71syce4n	78	28	progeny	progeny	NOUN
cord-301856-71syce4n	78	29	.	.	PUNCT
cord-301856-71syce4n	79	1	accordingly	accordingly	ADV
cord-301856-71syce4n	79	2	,	,	PUNCT
cord-301856-71syce4n	79	3	1	1	NUM
cord-301856-71syce4n	79	4	-	-	SYM
cord-301856-71syce4n	79	5	4	4	NUM
cord-301856-71syce4n	79	6	%	%	NOUN
cord-301856-71syce4n	79	7	of	of	ADP
cord-301856-71syce4n	79	8	the	the	DET
cord-301856-71syce4n	79	9	genome	genome	NOUN
cord-301856-71syce4n	79	10	of	of	ADP
cord-301856-71syce4n	79	11	european	european	ADJ
cord-301856-71syce4n	79	12	and	and	CCONJ
cord-301856-71syce4n	79	13	asian	asian	ADJ
cord-301856-71syce4n	79	14	populations	population	NOUN
cord-301856-71syce4n	79	15	is	be	AUX
cord-301856-71syce4n	79	16	thought	think	VERB
cord-301856-71syce4n	79	17	to	to	PART
cord-301856-71syce4n	79	18	derive	derive	VERB
cord-301856-71syce4n	79	19	from	from	ADP
cord-301856-71syce4n	79	20	these	these	DET
cord-301856-71syce4n	79	21	now	now	ADV
cord-301856-71syce4n	79	22	-	-	PUNCT
cord-301856-71syce4n	79	23	extinct	extinct	ADJ
cord-301856-71syce4n	79	24	hominid	hominid	ADJ
cord-301856-71syce4n	79	25	lineages	lineage	NOUN
cord-301856-71syce4n	79	26	[	[	X
cord-301856-71syce4n	79	27	23	23	NUM
cord-301856-71syce4n	79	28	]	]	PUNCT
cord-301856-71syce4n	79	29	.	.	PUNCT
cord-301856-71syce4n	80	1	neanderthals	neanderthal	NOUN
cord-301856-71syce4n	80	2	spent	spend	VERB
cord-301856-71syce4n	80	3	close	close	ADV
cord-301856-71syce4n	80	4	to	to	ADP
cord-301856-71syce4n	80	5	600	600	NUM
cord-301856-71syce4n	80	6	000	000	NUM
cord-301856-71syce4n	80	7	years	year	NOUN
cord-301856-71syce4n	80	8	adapting	adapt	VERB
cord-301856-71syce4n	80	9	to	to	ADP
cord-301856-71syce4n	80	10	their	their	PRON
cord-301856-71syce4n	80	11	environment	environment	NOUN
cord-301856-71syce4n	80	12	and	and	CCONJ
cord-301856-71syce4n	80	13	their	their	PRON
cord-301856-71syce4n	80	14	immune	immune	ADJ
cord-301856-71syce4n	80	15	systems	system	NOUN
cord-301856-71syce4n	80	16	were	be	AUX
cord-301856-71syce4n	80	17	shaped	shape	VERB
cord-301856-71syce4n	80	18	by	by	ADP
cord-301856-71syce4n	80	19	the	the	DET
cord-301856-71syce4n	80	20	infections	infection	NOUN
cord-301856-71syce4n	80	21	they	they	PRON
cord-301856-71syce4n	80	22	faced	face	VERB
cord-301856-71syce4n	80	23	.	.	PUNCT
cord-301856-71syce4n	81	1	by	by	ADP
cord-301856-71syce4n	81	2	interbreeding	interbreed	VERB
cord-301856-71syce4n	81	3	with	with	ADP
cord-301856-71syce4n	81	4	archaic	archaic	ADJ
cord-301856-71syce4n	81	5	humans	human	NOUN
cord-301856-71syce4n	81	6	,	,	PUNCT
cord-301856-71syce4n	81	7	modern	modern	ADJ
cord-301856-71syce4n	81	8	humans	human	NOUN
cord-301856-71syce4n	81	9	incorporated	incorporate	VERB
cord-301856-71syce4n	81	10	these	these	DET
cord-301856-71syce4n	81	11	advantageous	advantageous	ADJ
cord-301856-71syce4n	81	12	adaptations	adaptation	NOUN
cord-301856-71syce4n	81	13	in	in	ADP
cord-301856-71syce4n	81	14	the	the	DET
cord-301856-71syce4n	81	15	genome	genome	NOUN
cord-301856-71syce4n	81	16	of	of	ADP
cord-301856-71syce4n	81	17	their	their	PRON
cord-301856-71syce4n	81	18	descendants	descendant	NOUN
cord-301856-71syce4n	81	19	.	.	PUNCT
cord-301856-71syce4n	82	1	this	this	PRON
cord-301856-71syce4n	82	2	was	be	AUX
cord-301856-71syce4n	82	3	highlighted	highlight	VERB
cord-301856-71syce4n	82	4	by	by	ADP
cord-301856-71syce4n	82	5	different	different	ADJ
cord-301856-71syce4n	82	6	studies	study	NOUN
cord-301856-71syce4n	82	7	that	that	PRON
cord-301856-71syce4n	82	8	showed	show	VERB
cord-301856-71syce4n	82	9	that	that	SCONJ
cord-301856-71syce4n	82	10	the	the	DET
cord-301856-71syce4n	82	11	introgression	introgression	NOUN
cord-301856-71syce4n	82	12	of	of	ADP
cord-301856-71syce4n	82	13	diverse	diverse	ADJ
cord-301856-71syce4n	82	14	genes	gene	NOUN
cord-301856-71syce4n	82	15	related	relate	VERB
cord-301856-71syce4n	82	16	to	to	ADP
cord-301856-71syce4n	82	17	immune	immune	ADJ
cord-301856-71syce4n	82	18	functions	function	NOUN
cord-301856-71syce4n	82	19	,	,	PUNCT
cord-301856-71syce4n	82	20	such	such	ADJ
cord-301856-71syce4n	82	21	as	as	ADP
cord-301856-71syce4n	82	22	the	the	DET
cord-301856-71syce4n	82	23	oas	oas	PROPN
cord-301856-71syce4n	82	24	cluster	cluster	PROPN
cord-301856-71syce4n	82	25	,	,	PUNCT
cord-301856-71syce4n	82	26	tlr1	tlr1	PROPN
cord-301856-71syce4n	82	27	,	,	PUNCT
cord-301856-71syce4n	82	28	or	or	CCONJ
cord-301856-71syce4n	82	29	the	the	DET
cord-301856-71syce4n	82	30	histocompatibility	histocompatibility	NOUN
cord-301856-71syce4n	82	31	complex	complex	NOUN
cord-301856-71syce4n	82	32	from	from	ADP
cord-301856-71syce4n	82	33	denisovans	denisovan	NOUN
cord-301856-71syce4n	82	34	and	and	CCONJ
cord-301856-71syce4n	82	35	neanderthals	neanderthal	NOUN
cord-301856-71syce4n	82	36	shaped	shape	VERB
cord-301856-71syce4n	82	37	the	the	DET
cord-301856-71syce4n	82	38	genetic	genetic	ADJ
cord-301856-71syce4n	82	39	landscape	landscape	NOUN
cord-301856-71syce4n	82	40	of	of	ADP
cord-301856-71syce4n	82	41	present	present	ADJ
cord-301856-71syce4n	82	42	-	-	PUNCT
cord-301856-71syce4n	82	43	day	day	NOUN
cord-301856-71syce4n	82	44	eurasian	eurasian	ADJ
cord-301856-71syce4n	82	45	,	,	PUNCT
cord-301856-71syce4n	82	46	but	but	CCONJ
cord-301856-71syce4n	82	47	not	not	PART
cord-301856-71syce4n	82	48	african	african	ADJ
cord-301856-71syce4n	82	49	,	,	PUNCT
cord-301856-71syce4n	82	50	communities	community	NOUN
cord-301856-71syce4n	82	51	.	.	PUNCT
cord-301856-71syce4n	83	1	genomic	genomic	NOUN
cord-301856-71syce4n	83	2	sequences	sequence	NOUN
cord-301856-71syce4n	83	3	and	and	CCONJ
cord-301856-71syce4n	83	4	expression	expression	NOUN
cord-301856-71syce4n	83	5	data	datum	NOUN
cord-301856-71syce4n	83	6	from	from	ADP
cord-301856-71syce4n	83	7	lymphoblastoid	lymphoblastoid	NOUN
cord-301856-71syce4n	83	8	cell	cell	NOUN
cord-301856-71syce4n	83	9	lines	line	NOUN
cord-301856-71syce4n	83	10	from	from	ADP
cord-301856-71syce4n	83	11	421	421	NUM
cord-301856-71syce4n	83	12	individuals	individual	NOUN
cord-301856-71syce4n	83	13	of	of	ADP
cord-301856-71syce4n	83	14	european	european	ADJ
cord-301856-71syce4n	83	15	and	and	CCONJ
cord-301856-71syce4n	83	16	african	african	PROPN
cord-301856-71syce4n	83	17	ancestry	ancestry	PROPN
cord-301856-71syce4n	83	18	confirmed	confirm	VERB
cord-301856-71syce4n	83	19	that	that	SCONJ
cord-301856-71syce4n	83	20	the	the	DET
cord-301856-71syce4n	83	21	tlr1	tlr1	PROPN
cord-301856-71syce4n	83	22	-	-	PUNCT
cord-301856-71syce4n	83	23	tlr6	tlr6	PROPN
cord-301856-71syce4n	83	24	-	-	PUNCT
cord-301856-71syce4n	83	25	tlr10	tlr10	VERB
cord-301856-71syce4n	83	26	genetic	genetic	ADJ
cord-301856-71syce4n	83	27	loci	loci	NOUN
cord-301856-71syce4n	83	28	,	,	PUNCT
cord-301856-71syce4n	83	29	presenting	present	VERB
cord-301856-71syce4n	83	30	signs	sign	NOUN
cord-301856-71syce4n	83	31	of	of	ADP
cord-301856-71syce4n	83	32	local	local	ADJ
cord-301856-71syce4n	83	33	positive	positive	ADJ
cord-301856-71syce4n	83	34	selection	selection	NOUN
cord-301856-71syce4n	83	35	and	and	CCONJ
cord-301856-71syce4n	83	36	repeated	repeat	VERB
cord-301856-71syce4n	83	37	introgression	introgression	NOUN
cord-301856-71syce4n	83	38	from	from	ADP
cord-301856-71syce4n	83	39	both	both	PRON
cord-301856-71syce4n	83	40	neanderthal	neanderthal	NOUN
cord-301856-71syce4n	83	41	and	and	CCONJ
cord-301856-71syce4n	83	42	denisovan	denisovan	ADJ
cord-301856-71syce4n	83	43	genomes	genome	NOUN
cord-301856-71syce4n	83	44	[	[	X
cord-301856-71syce4n	83	45	24	24	NUM
cord-301856-71syce4n	83	46	]	]	PUNCT
cord-301856-71syce4n	83	47	[	[	X
cord-301856-71syce4n	83	48	25	25	NUM
cord-301856-71syce4n	83	49	]	]	PUNCT
cord-301856-71syce4n	83	50	[	[	X
cord-301856-71syce4n	83	51	26	26	NUM
cord-301856-71syce4n	83	52	]	]	PUNCT
cord-301856-71syce4n	83	53	,	,	PUNCT
cord-301856-71syce4n	83	54	showed	show	VERB
cord-301856-71syce4n	83	55	a	a	DET
cord-301856-71syce4n	83	56	significantly	significantly	ADV
cord-301856-71syce4n	83	57	higher	high	ADJ
cord-301856-71syce4n	83	58	expression	expression	NOUN
cord-301856-71syce4n	83	59	in	in	ADP
cord-301856-71syce4n	83	60	individuals	individual	NOUN
cord-301856-71syce4n	83	61	carrying	carry	VERB
cord-301856-71syce4n	83	62	archaic	archaic	ADJ
cord-301856-71syce4n	83	63	-	-	PUNCT
cord-301856-71syce4n	83	64	like	like	ADJ
cord-301856-71syce4n	83	65	alleles	allele	NOUN
cord-301856-71syce4n	83	66	than	than	ADP
cord-301856-71syce4n	83	67	in	in	ADP
cord-301856-71syce4n	83	68	individuals	individual	NOUN
cord-301856-71syce4n	83	69	carrying	carry	VERB
cord-301856-71syce4n	83	70	the	the	DET
cord-301856-71syce4n	83	71	nonintrogressed	nonintrogressed	ADJ
cord-301856-71syce4n	83	72	modern	modern	ADJ
cord-301856-71syce4n	83	73	human	human	ADJ
cord-301856-71syce4n	83	74	alleles	allele	NOUN
cord-301856-71syce4n	83	75	[	[	PUNCT
cord-301856-71syce4n	83	76	2	2	NUM
cord-301856-71syce4n	83	77	,	,	PUNCT
cord-301856-71syce4n	83	78	26	26	NUM
cord-301856-71syce4n	83	79	,	,	PUNCT
cord-301856-71syce4n	83	80	27	27	NUM
cord-301856-71syce4n	83	81	]	]	PUNCT
cord-301856-71syce4n	83	82	.	.	PUNCT
cord-301856-71syce4n	84	1	the	the	DET
cord-301856-71syce4n	84	2	expression	expression	NOUN
cord-301856-71syce4n	84	3	of	of	ADP
cord-301856-71syce4n	84	4	these	these	DET
cord-301856-71syce4n	84	5	genes	gene	NOUN
cord-301856-71syce4n	84	6	has	have	AUX
cord-301856-71syce4n	84	7	shaped	shape	VERB
cord-301856-71syce4n	84	8	human	human	ADJ
cord-301856-71syce4n	84	9	immune	immune	ADJ
cord-301856-71syce4n	84	10	responses	response	NOUN
cord-301856-71syce4n	84	11	against	against	ADP
cord-301856-71syce4n	84	12	different	different	ADJ
cord-301856-71syce4n	84	13	types	type	NOUN
cord-301856-71syce4n	84	14	of	of	ADP
cord-301856-71syce4n	84	15	pathogens	pathogen	NOUN
cord-301856-71syce4n	84	16	.	.	PUNCT
cord-301856-71syce4n	85	1	for	for	ADP
cord-301856-71syce4n	85	2	example	example	NOUN
cord-301856-71syce4n	85	3	,	,	PUNCT
cord-301856-71syce4n	85	4	the	the	DET
cord-301856-71syce4n	85	5	gp41	gp41	PROPN
cord-301856-71syce4n	85	6	protein	protein	NOUN
cord-301856-71syce4n	85	7	of	of	ADP
cord-301856-71syce4n	85	8	the	the	DET
cord-301856-71syce4n	85	9	hiv-1	hiv-1	PUNCT
cord-301856-71syce4n	85	10	virus	virus	NOUN
cord-301856-71syce4n	85	11	has	have	AUX
cord-301856-71syce4n	85	12	been	be	AUX
cord-301856-71syce4n	85	13	recently	recently	ADV
cord-301856-71syce4n	85	14	recognized	recognize	VERB
cord-301856-71syce4n	85	15	as	as	ADP
cord-301856-71syce4n	85	16	a	a	DET
cord-301856-71syce4n	85	17	tlr10	tlr10	PROPN
cord-301856-71syce4n	85	18	ligand	ligand	NOUN
cord-301856-71syce4n	85	19	[	[	PUNCT
cord-301856-71syce4n	85	20	28	28	NUM
cord-301856-71syce4n	85	21	]	]	PUNCT
cord-301856-71syce4n	85	22	.	.	PUNCT
cord-301856-71syce4n	86	1	in	in	ADP
cord-301856-71syce4n	86	2	this	this	DET
cord-301856-71syce4n	86	3	regard	regard	NOUN
cord-301856-71syce4n	86	4	,	,	PUNCT
cord-301856-71syce4n	86	5	increased	increase	VERB
cord-301856-71syce4n	86	6	tlr10	tlr10	PROPN
cord-301856-71syce4n	86	7	expression	expression	NOUN
cord-301856-71syce4n	86	8	has	have	AUX
cord-301856-71syce4n	86	9	been	be	AUX
cord-301856-71syce4n	86	10	correlated	correlate	VERB
cord-301856-71syce4n	86	11	with	with	ADP
cord-301856-71syce4n	86	12	higher	high	ADJ
cord-301856-71syce4n	86	13	il-8	il-8	ADJ
cord-301856-71syce4n	86	14	production	production	NOUN
cord-301856-71syce4n	86	15	by	by	ADP
cord-301856-71syce4n	86	16	the	the	DET
cord-301856-71syce4n	86	17	macrophage	macrophage	NOUN
cord-301856-71syce4n	86	18	cell	cell	NOUN
cord-301856-71syce4n	86	19	line	line	NOUN
cord-301856-71syce4n	86	20	thp-1	thp-1	NOUN
cord-301856-71syce4n	86	21	and	and	CCONJ
cord-301856-71syce4n	86	22	higher	high	ADJ
cord-301856-71syce4n	86	23	titers	titer	NOUN
cord-301856-71syce4n	86	24	of	of	ADP
cord-301856-71syce4n	86	25	hiv-1	hiv-1	PUNCT
cord-301856-71syce4n	86	26	in	in	ADP
cord-301856-71syce4n	86	27	the	the	DET
cord-301856-71syce4n	86	28	breast	breast	NOUN
cord-301856-71syce4n	86	29	milk	milk	NOUN
cord-301856-71syce4n	86	30	of	of	ADP
cord-301856-71syce4n	86	31	hiv-1	hiv-1	SYM
cord-301856-71syce4n	86	32	-	-	PUNCT
cord-301856-71syce4n	86	33	infected	infect	VERB
cord-301856-71syce4n	86	34	nigerian	nigerian	ADJ
cord-301856-71syce4n	86	35	women	woman	NOUN
cord-301856-71syce4n	86	36	relative	relative	ADJ
cord-301856-71syce4n	86	37	to	to	ADP
cord-301856-71syce4n	86	38	controls	control	NOUN
cord-301856-71syce4n	86	39	[	[	SYM
cord-301856-71syce4n	86	40	28	28	NUM
cord-301856-71syce4n	86	41	]	]	PUNCT
cord-301856-71syce4n	86	42	.	.	PUNCT
cord-301856-71syce4n	87	1	tlr1	tlr1	PROPN
cord-301856-71syce4n	87	2	and	and	CCONJ
cord-301856-71syce4n	87	3	tlr6	tlr6	PROPN
cord-301856-71syce4n	87	4	form	form	VERB
cord-301856-71syce4n	87	5	dimers	dimer	NOUN
cord-301856-71syce4n	87	6	with	with	ADP
cord-301856-71syce4n	87	7	tlr2	tlr2	PROPN
cord-301856-71syce4n	87	8	,	,	PUNCT
cord-301856-71syce4n	87	9	triggering	trigger	VERB
cord-301856-71syce4n	87	10	immune	immune	ADJ
cord-301856-71syce4n	87	11	responses	response	NOUN
cord-301856-71syce4n	87	12	against	against	ADP
cord-301856-71syce4n	87	13	different	different	ADJ
cord-301856-71syce4n	87	14	types	type	NOUN
cord-301856-71syce4n	87	15	of	of	ADP
cord-301856-71syce4n	87	16	bacteria	bacteria	NOUN
cord-301856-71syce4n	87	17	,	,	PUNCT
cord-301856-71syce4n	87	18	fungi	fungi	PROPN
cord-301856-71syce4n	87	19	,	,	PUNCT
cord-301856-71syce4n	87	20	virus	virus	NOUN
cord-301856-71syce4n	87	21	,	,	PUNCT
cord-301856-71syce4n	87	22	and	and	CCONJ
cord-301856-71syce4n	87	23	parasites	parasite	NOUN
cord-301856-71syce4n	87	24	[	[	PUNCT
cord-301856-71syce4n	87	25	29	29	NUM
cord-301856-71syce4n	87	26	]	]	PUNCT
cord-301856-71syce4n	87	27	.	.	PUNCT
cord-301856-71syce4n	88	1	variation	variation	NOUN
cord-301856-71syce4n	88	2	in	in	ADP
cord-301856-71syce4n	88	3	tlr1	tlr1	PROPN
cord-301856-71syce4n	88	4	-	-	PUNCT
cord-301856-71syce4n	88	5	tlr6	tlr6	PROPN
cord-301856-71syce4n	88	6	-	-	PUNCT
cord-301856-71syce4n	88	7	tlr10	tlr10	PROPN
cord-301856-71syce4n	88	8	is	be	AUX
cord-301856-71syce4n	88	9	the	the	DET
cord-301856-71syce4n	88	10	major	major	ADJ
cord-301856-71syce4n	88	11	genetic	genetic	ADJ
cord-301856-71syce4n	88	12	determinant	determinant	NOUN
cord-301856-71syce4n	88	13	of	of	ADP
cord-301856-71syce4n	88	14	human	human	ADJ
cord-301856-71syce4n	88	15	interindividual	interindividual	ADJ
cord-301856-71syce4n	88	16	differences	difference	NOUN
cord-301856-71syce4n	88	17	in	in	ADP
cord-301856-71syce4n	88	18	tlr1/2	tlr1/2	ADV
cord-301856-71syce4n	88	19	-	-	PUNCT
cord-301856-71syce4n	88	20	mediated	mediate	VERB
cord-301856-71syce4n	88	21	responses	response	NOUN
cord-301856-71syce4n	88	22	,	,	PUNCT
cord-301856-71syce4n	88	23	including	include	VERB
cord-301856-71syce4n	88	24	cytokine	cytokine	NOUN
cord-301856-71syce4n	88	25	production	production	NOUN
cord-301856-71syce4n	88	26	to	to	ADP
cord-301856-71syce4n	88	27	a	a	DET
cord-301856-71syce4n	88	28	number	number	NOUN
cord-301856-71syce4n	88	29	of	of	ADP
cord-301856-71syce4n	88	30	clinically	clinically	ADV
cord-301856-71syce4n	88	31	relevant	relevant	ADJ
cord-301856-71syce4n	88	32	pathogens	pathogen	NOUN
cord-301856-71syce4n	88	33	such	such	ADJ
cord-301856-71syce4n	88	34	as	as	ADP
cord-301856-71syce4n	88	35	staphylococcus	staphylococcus	NOUN
cord-301856-71syce4n	88	36	aureus	aureus	NOUN
cord-301856-71syce4n	88	37	and	and	CCONJ
cord-301856-71syce4n	88	38	listeria	listeria	VERB
cord-301856-71syce4n	88	39	monocytogenes	monocytogene	NOUN
cord-301856-71syce4n	88	40	[	[	PUNCT
cord-301856-71syce4n	88	41	30	30	NUM
cord-301856-71syce4n	88	42	]	]	PUNCT
cord-301856-71syce4n	88	43	(	(	PUNCT
cord-301856-71syce4n	88	44	table	table	NOUN
cord-301856-71syce4n	88	45	1	1	NUM
cord-301856-71syce4n	88	46	)	)	PUNCT
cord-301856-71syce4n	88	47	.	.	PUNCT
cord-301856-71syce4n	89	1	this	this	DET
cord-301856-71syce4n	89	2	inheritance	inheritance	NOUN
cord-301856-71syce4n	89	3	from	from	ADP
cord-301856-71syce4n	89	4	archaic	archaic	ADJ
cord-301856-71syce4n	89	5	humans	human	NOUN
cord-301856-71syce4n	89	6	may	may	AUX
cord-301856-71syce4n	89	7	have	have	AUX
cord-301856-71syce4n	89	8	also	also	ADV
cord-301856-71syce4n	89	9	left	leave	VERB
cord-301856-71syce4n	89	10	some	some	DET
cord-301856-71syce4n	89	11	human	human	ADJ
cord-301856-71syce4n	89	12	individuals	individual	NOUN
cord-301856-71syce4n	89	13	more	more	ADV
cord-301856-71syce4n	89	14	prone	prone	ADJ
cord-301856-71syce4n	89	15	than	than	ADP
cord-301856-71syce4n	89	16	others	other	NOUN
cord-301856-71syce4n	89	17	to	to	ADP
cord-301856-71syce4n	89	18	developing	develop	VERB
cord-301856-71syce4n	89	19	asthma	asthma	NOUN
cord-301856-71syce4n	89	20	,	,	PUNCT
cord-301856-71syce4n	89	21	hay	hay	NOUN
cord-301856-71syce4n	89	22	fever	fever	NOUN
cord-301856-71syce4n	89	23	,	,	PUNCT
cord-301856-71syce4n	89	24	and	and	CCONJ
cord-301856-71syce4n	89	25	other	other	ADJ
cord-301856-71syce4n	89	26	allergies	allergy	NOUN
cord-301856-71syce4n	89	27	(	(	PUNCT
cord-301856-71syce4n	89	28	of	of	ADP
cord-301856-71syce4n	89	29	58	58	NUM
cord-301856-71syce4n	89	30	snps	snps	NOUN
cord-301856-71syce4n	89	31	associated	associate	VERB
cord-301856-71syce4n	89	32	with	with	ADP
cord-301856-71syce4n	89	33	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	89	34	to	to	ADP
cord-301856-71syce4n	89	35	allergic	allergic	ADJ
cord-301856-71syce4n	89	36	disease	disease	NOUN
cord-301856-71syce4n	89	37	,	,	PUNCT
cord-301856-71syce4n	89	38	12	12	NUM
cord-301856-71syce4n	89	39	had	have	VERB
cord-301856-71syce4n	89	40	a	a	DET
cord-301856-71syce4n	89	41	neanderthal	neanderthal	NOUN
cord-301856-71syce4n	89	42	or	or	CCONJ
cord-301856-71syce4n	89	43	denisovan	denisovan	ADJ
cord-301856-71syce4n	89	44	origin	origin	NOUN
cord-301856-71syce4n	89	45	)	)	PUNCT
cord-301856-71syce4n	90	1	[	[	PUNCT
cord-301856-71syce4n	90	2	26	26	NUM
cord-301856-71syce4n	90	3	]	]	PUNCT
cord-301856-71syce4n	90	4	,	,	PUNCT
cord-301856-71syce4n	90	5	although	although	SCONJ
cord-301856-71syce4n	90	6	these	these	DET
cord-301856-71syce4n	90	7	associations	association	NOUN
cord-301856-71syce4n	90	8	remain	remain	VERB
cord-301856-71syce4n	90	9	to	to	PART
cord-301856-71syce4n	90	10	be	be	AUX
cord-301856-71syce4n	90	11	fully	fully	ADV
cord-301856-71syce4n	90	12	demonstrated	demonstrate	VERB
cord-301856-71syce4n	90	13	[	[	X
cord-301856-71syce4n	90	14	31	31	NUM
cord-301856-71syce4n	90	15	]	]	PUNCT
cord-301856-71syce4n	90	16	.	.	PUNCT
cord-301856-71syce4n	91	1	these	these	DET
cord-301856-71syce4n	91	2	reports	report	NOUN
cord-301856-71syce4n	91	3	demonstrate	demonstrate	VERB
cord-301856-71syce4n	91	4	that	that	SCONJ
cord-301856-71syce4n	91	5	by	by	ADP
cord-301856-71syce4n	91	6	interbreeding	interbreed	VERB
cord-301856-71syce4n	91	7	with	with	ADP
cord-301856-71syce4n	91	8	archaic	archaic	ADJ
cord-301856-71syce4n	91	9	humans	human	NOUN
cord-301856-71syce4n	91	10	,	,	PUNCT
cord-301856-71syce4n	91	11	modern	modern	ADJ
cord-301856-71syce4n	91	12	humans	human	NOUN
cord-301856-71syce4n	91	13	incorporated	incorporate	VERB
cord-301856-71syce4n	91	14	a	a	DET
cord-301856-71syce4n	91	15	group	group	NOUN
cord-301856-71syce4n	91	16	of	of	ADP
cord-301856-71syce4n	91	17	advantageous	advantageous	ADJ
cord-301856-71syce4n	91	18	adaptations	adaptation	NOUN
cord-301856-71syce4n	91	19	to	to	ADP
cord-301856-71syce4n	91	20	the	the	DET
cord-301856-71syce4n	91	21	genome	genome	NOUN
cord-301856-71syce4n	91	22	of	of	ADP
cord-301856-71syce4n	91	23	their	their	PRON
cord-301856-71syce4n	91	24	descendants	descendant	NOUN
cord-301856-71syce4n	91	25	and	and	CCONJ
cord-301856-71syce4n	91	26	contributed	contribute	VERB
cord-301856-71syce4n	91	27	to	to	ADP
cord-301856-71syce4n	91	28	shaping	shape	VERB
cord-301856-71syce4n	91	29	immune	immune	ADJ
cord-301856-71syce4n	91	30	responses	response	NOUN
cord-301856-71syce4n	91	31	in	in	ADP
cord-301856-71syce4n	91	32	modern	modern	ADJ
cord-301856-71syce4n	91	33	human	human	ADJ
cord-301856-71syce4n	91	34	populations	population	NOUN
cord-301856-71syce4n	91	35	.	.	PUNCT
cord-301856-71syce4n	92	1	the	the	DET
cord-301856-71syce4n	92	2	migration	migration	NOUN
cord-301856-71syce4n	92	3	of	of	ADP
cord-301856-71syce4n	92	4	our	our	PRON
cord-301856-71syce4n	92	5	human	human	ADJ
cord-301856-71syce4n	92	6	ancestors	ancestor	NOUN
cord-301856-71syce4n	92	7	out	out	ADP
cord-301856-71syce4n	92	8	of	of	ADP
cord-301856-71syce4n	92	9	africa	africa	PROPN
cord-301856-71syce4n	92	10	implied	imply	VERB
cord-301856-71syce4n	92	11	the	the	DET
cord-301856-71syce4n	92	12	exposure	exposure	NOUN
cord-301856-71syce4n	92	13	to	to	ADP
cord-301856-71syce4n	92	14	different	different	ADJ
cord-301856-71syce4n	92	15	types	type	NOUN
cord-301856-71syce4n	92	16	of	of	ADP
cord-301856-71syce4n	92	17	infectious	infectious	ADJ
cord-301856-71syce4n	92	18	diseases	disease	NOUN
cord-301856-71syce4n	92	19	(	(	PUNCT
cord-301856-71syce4n	92	20	box	box	NOUN
cord-301856-71syce4n	92	21	2	2	NUM
cord-301856-71syce4n	92	22	and	and	CCONJ
cord-301856-71syce4n	92	23	figure	figure	VERB
cord-301856-71syce4n	92	24	3	3	NUM
cord-301856-71syce4n	92	25	)	)	PUNCT
cord-301856-71syce4n	92	26	.	.	PUNCT
cord-301856-71syce4n	93	1	one	one	NUM
cord-301856-71syce4n	93	2	study	study	NOUN
cord-301856-71syce4n	93	3	tested	test	VERB
cord-301856-71syce4n	93	4	the	the	DET
cord-301856-71syce4n	93	5	responsiveness	responsiveness	NOUN
cord-301856-71syce4n	93	6	of	of	ADP
cord-301856-71syce4n	93	7	human	human	ADJ
cord-301856-71syce4n	93	8	macrophages	macrophage	NOUN
cord-301856-71syce4n	93	9	to	to	ADP
cord-301856-71syce4n	93	10	pathogenic	pathogenic	ADJ
cord-301856-71syce4n	93	11	bacteria	bacteria	NOUN
cord-301856-71syce4n	93	12	in	in	ADP
cord-301856-71syce4n	93	13	vitro	vitro	X
cord-301856-71syce4n	93	14	,	,	PUNCT
cord-301856-71syce4n	93	15	finding	find	VERB
cord-301856-71syce4n	93	16	that	that	SCONJ
cord-301856-71syce4n	93	17	almost	almost	ADV
cord-301856-71syce4n	93	18	10	10	NUM
cord-301856-71syce4n	93	19	%	%	NOUN
cord-301856-71syce4n	93	20	of	of	ADP
cord-301856-71syce4n	93	21	the	the	DET
cord-301856-71syce4n	93	22	genes	gene	NOUN
cord-301856-71syce4n	93	23	present	present	ADJ
cord-301856-71syce4n	93	24	in	in	ADP
cord-301856-71syce4n	93	25	human	human	ADJ
cord-301856-71syce4n	93	26	macrophages	macrophage	NOUN
cord-301856-71syce4n	93	27	infected	infect	VERB
cord-301856-71syce4n	93	28	with	with	ADP
cord-301856-71syce4n	93	29	the	the	DET
cord-301856-71syce4n	93	30	bacteria	bacteria	NOUN
cord-301856-71syce4n	93	31	salmonella	salmonella	PROPN
cord-301856-71syce4n	93	32	typhimurium	typhimurium	PROPN
cord-301856-71syce4n	93	33	or	or	CCONJ
cord-301856-71syce4n	93	34	l.	l.	PROPN
cord-301856-71syce4n	93	35	monocytogenes	monocytogene	NOUN
cord-301856-71syce4n	93	36	present	present	VERB
cord-301856-71syce4n	93	37	different	different	ADJ
cord-301856-71syce4n	93	38	regulatory	regulatory	ADJ
cord-301856-71syce4n	93	39	responses	response	NOUN
cord-301856-71syce4n	93	40	directly	directly	ADV
cord-301856-71syce4n	93	41	linked	link	VERB
cord-301856-71syce4n	93	42	to	to	ADP
cord-301856-71syce4n	93	43	the	the	DET
cord-301856-71syce4n	93	44	lineage	lineage	NOUN
cord-301856-71syce4n	93	45	of	of	ADP
cord-301856-71syce4n	93	46	the	the	DET
cord-301856-71syce4n	93	47	donors	donor	NOUN
cord-301856-71syce4n	93	48	and	and	CCONJ
cord-301856-71syce4n	93	49	,	,	PUNCT
cord-301856-71syce4n	93	50	also	also	ADV
cord-301856-71syce4n	93	51	,	,	PUNCT
cord-301856-71syce4n	93	52	that	that	SCONJ
cord-301856-71syce4n	93	53	macrophages	macrophage	NOUN
cord-301856-71syce4n	93	54	obtained	obtain	VERB
cord-301856-71syce4n	93	55	from	from	ADP
cord-301856-71syce4n	93	56	individuals	individual	NOUN
cord-301856-71syce4n	93	57	of	of	ADP
cord-301856-71syce4n	93	58	african	african	ADJ
cord-301856-71syce4n	93	59	origin	origin	NOUN
cord-301856-71syce4n	93	60	display	display	NOUN
cord-301856-71syce4n	93	61	enhanced	enhance	VERB
cord-301856-71syce4n	93	62	bactericidal	bactericidal	ADJ
cord-301856-71syce4n	93	63	activity	activity	NOUN
cord-301856-71syce4n	93	64	compared	compare	VERB
cord-301856-71syce4n	93	65	with	with	ADP
cord-301856-71syce4n	93	66	those	those	PRON
cord-301856-71syce4n	93	67	from	from	ADP
cord-301856-71syce4n	93	68	individuals	individual	NOUN
cord-301856-71syce4n	93	69	of	of	ADP
cord-301856-71syce4n	93	70	european	european	ADJ
cord-301856-71syce4n	93	71	lineage	lineage	NOUN
cord-301856-71syce4n	93	72	[	[	PUNCT
cord-301856-71syce4n	93	73	32	32	NUM
cord-301856-71syce4n	93	74	]	]	PUNCT
cord-301856-71syce4n	93	75	.	.	PUNCT
cord-301856-71syce4n	94	1	the	the	DET
cord-301856-71syce4n	94	2	trend	trend	NOUN
cord-301856-71syce4n	94	3	towards	towards	ADP
cord-301856-71syce4n	94	4	lower	low	ADJ
cord-301856-71syce4n	94	5	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	94	6	responses	response	NOUN
cord-301856-71syce4n	94	7	in	in	ADP
cord-301856-71syce4n	94	8	european	european	ADJ
cord-301856-71syce4n	94	9	populations	population	NOUN
cord-301856-71syce4n	94	10	is	be	AUX
cord-301856-71syce4n	94	11	strengthened	strengthen	VERB
cord-301856-71syce4n	94	12	by	by	ADP
cord-301856-71syce4n	94	13	the	the	DET
cord-301856-71syce4n	94	14	fixation	fixation	NOUN
cord-301856-71syce4n	94	15	of	of	ADP
cord-301856-71syce4n	94	16	a	a	DET
cord-301856-71syce4n	94	17	tlr1	tlr1	PROPN
cord-301856-71syce4n	94	18	gene	gene	NOUN
cord-301856-71syce4n	94	19	variant	variant	NOUN
cord-301856-71syce4n	94	20	that	that	PRON
cord-301856-71syce4n	94	21	results	result	VERB
cord-301856-71syce4n	94	22	in	in	ADP
cord-301856-71syce4n	94	23	lower	low	ADJ
cord-301856-71syce4n	94	24	proinflammatory	proinflammatory	ADJ
cord-301856-71syce4n	94	25	gene	gene	NOUN
cord-301856-71syce4n	94	26	expression	expression	NOUN
cord-301856-71syce4n	94	27	in	in	ADP
cord-301856-71syce4n	94	28	populations	population	NOUN
cord-301856-71syce4n	94	29	with	with	ADP
cord-301856-71syce4n	94	30	a	a	DET
cord-301856-71syce4n	94	31	european	european	ADJ
cord-301856-71syce4n	94	32	ancestry	ancestry	NOUN
cord-301856-71syce4n	94	33	compared	compare	VERB
cord-301856-71syce4n	94	34	with	with	ADP
cord-301856-71syce4n	94	35	those	those	PRON
cord-301856-71syce4n	94	36	with	with	ADP
cord-301856-71syce4n	94	37	an	an	DET
cord-301856-71syce4n	94	38	african	african	ADJ
cord-301856-71syce4n	94	39	one	one	NUM
cord-301856-71syce4n	94	40	[	[	PUNCT
cord-301856-71syce4n	94	41	33	33	NUM
cord-301856-71syce4n	94	42	]	]	PUNCT
cord-301856-71syce4n	94	43	.	.	PUNCT
cord-301856-71syce4n	95	1	the	the	DET
cord-301856-71syce4n	95	2	largest	large	ADJ
cord-301856-71syce4n	95	3	population	population	NOUN
cord-301856-71syce4n	95	4	differences	difference	NOUN
cord-301856-71syce4n	95	5	in	in	ADP
cord-301856-71syce4n	95	6	gene	gene	NOUN
cord-301856-71syce4n	95	7	expression	expression	NOUN
cord-301856-71syce4n	95	8	between	between	ADP
cord-301856-71syce4n	95	9	africans	africans	PROPN
cord-301856-71syce4n	95	10	and	and	CCONJ
cord-301856-71syce4n	95	11	europeans	europeans	PROPN
cord-301856-71syce4n	95	12	have	have	AUX
cord-301856-71syce4n	95	13	been	be	AUX
cord-301856-71syce4n	95	14	found	find	VERB
cord-301856-71syce4n	95	15	in	in	ADP
cord-301856-71syce4n	95	16	the	the	DET
cord-301856-71syce4n	95	17	macrophage	macrophage	NOUN
cord-301856-71syce4n	95	18	receptor	receptor	NOUN
cord-301856-71syce4n	95	19	with	with	ADP
cord-301856-71syce4n	95	20	collagenous	collagenous	ADJ
cord-301856-71syce4n	95	21	structure	structure	NOUN
cord-301856-71syce4n	95	22	(	(	PUNCT
cord-301856-71syce4n	95	23	marco	marco	PROPN
cord-301856-71syce4n	95	24	)	)	PUNCT
cord-301856-71syce4n	95	25	,	,	PUNCT
cord-301856-71syce4n	95	26	a	a	DET
cord-301856-71syce4n	95	27	protein	protein	NOUN
cord-301856-71syce4n	95	28	implicated	implicate	VERB
cord-301856-71syce4n	95	29	in	in	ADP
cord-301856-71syce4n	95	30	responses	response	NOUN
cord-301856-71syce4n	95	31	against	against	ADP
cord-301856-71syce4n	95	32	viral	viral	ADJ
cord-301856-71syce4n	95	33	infections	infection	NOUN
cord-301856-71syce4n	95	34	and	and	CCONJ
cord-301856-71syce4n	95	35	tlr	tlr	PROPN
cord-301856-71syce4n	95	36	-	-	PUNCT
cord-301856-71syce4n	95	37	induced	induce	VERB
cord-301856-71syce4n	95	38	dendritic	dendritic	ADJ
cord-301856-71syce4n	95	39	cell	cell	NOUN
cord-301856-71syce4n	95	40	activation	activation	NOUN
cord-301856-71syce4n	95	41	[	[	X
cord-301856-71syce4n	95	42	34	34	NUM
cord-301856-71syce4n	95	43	]	]	PUNCT
cord-301856-71syce4n	95	44	,	,	PUNCT
cord-301856-71syce4n	95	45	the	the	DET
cord-301856-71syce4n	95	46	chemokine	chemokine	NOUN
cord-301856-71syce4n	95	47	receptor	receptor	PROPN
cord-301856-71syce4n	95	48	cx3cr1	cx3cr1	PROPN
cord-301856-71syce4n	95	49	,	,	PUNCT
cord-301856-71syce4n	95	50	which	which	PRON
cord-301856-71syce4n	95	51	mediates	mediate	VERB
cord-301856-71syce4n	95	52	effector	effector	NOUN
cord-301856-71syce4n	95	53	lymphocyte	lymphocyte	NOUN
cord-301856-71syce4n	95	54	functions	function	NOUN
cord-301856-71syce4n	95	55	,	,	PUNCT
cord-301856-71syce4n	95	56	and	and	CCONJ
cord-301856-71syce4n	95	57	also	also	ADV
cord-301856-71syce4n	95	58	several	several	ADJ
cord-301856-71syce4n	95	59	ifn	ifn	ADJ
cord-301856-71syce4n	95	60	-	-	PUNCT
cord-301856-71syce4n	95	61	stimulated	stimulate	VERB
cord-301856-71syce4n	95	62	genes	gene	NOUN
cord-301856-71syce4n	95	63	[	[	X
cord-301856-71syce4n	95	64	35	35	NUM
cord-301856-71syce4n	95	65	]	]	PUNCT
cord-301856-71syce4n	95	66	.	.	PUNCT
cord-301856-71syce4n	96	1	west	west	PROPN
cord-301856-71syce4n	96	2	eurasian	eurasian	ADJ
cord-301856-71syce4n	96	3	populations	population	NOUN
cord-301856-71syce4n	96	4	present	present	VERB
cord-301856-71syce4n	96	5	a	a	DET
cord-301856-71syce4n	96	6	high	high	ADJ
cord-301856-71syce4n	96	7	frequency	frequency	NOUN
cord-301856-71syce4n	96	8	of	of	ADP
cord-301856-71syce4n	96	9	tirap	tirap	PROPN
cord-301856-71syce4n	96	10	ser180leu	ser180leu	PROPN
cord-301856-71syce4n	96	11	snps	snps	PROPN
cord-301856-71syce4n	97	1	[	[	X
cord-301856-71syce4n	97	2	36	36	NUM
cord-301856-71syce4n	97	3	]	]	PUNCT
cord-301856-71syce4n	97	4	.	.	PUNCT
cord-301856-71syce4n	98	1	tirap	tirap	PROPN
cord-301856-71syce4n	98	2	is	be	AUX
cord-301856-71syce4n	98	3	an	an	DET
cord-301856-71syce4n	98	4	adaptor	adaptor	NOUN
cord-301856-71syce4n	98	5	protein	protein	NOUN
cord-301856-71syce4n	98	6	in	in	ADP
cord-301856-71syce4n	98	7	tlr2	tlr2	PROPN
cord-301856-71syce4n	98	8	and	and	CCONJ
cord-301856-71syce4n	98	9	tlr4	tlr4	PROPN
cord-301856-71syce4n	98	10	signaling	signal	VERB
cord-301856-71syce4n	98	11	pathways	pathway	NOUN
cord-301856-71syce4n	98	12	,	,	PUNCT
cord-301856-71syce4n	98	13	involved	involve	VERB
cord-301856-71syce4n	98	14	in	in	ADP
cord-301856-71syce4n	98	15	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	98	16	responses	response	NOUN
cord-301856-71syce4n	98	17	and	and	CCONJ
cord-301856-71syce4n	98	18	cytokine	cytokine	NOUN
cord-301856-71syce4n	98	19	production	production	NOUN
cord-301856-71syce4n	98	20	.	.	PUNCT
cord-301856-71syce4n	99	1	the	the	DET
cord-301856-71syce4n	99	2	heterozygous	heterozygous	ADJ
cord-301856-71syce4n	99	3	expression	expression	NOUN
cord-301856-71syce4n	99	4	of	of	ADP
cord-301856-71syce4n	99	5	the	the	DET
cord-301856-71syce4n	99	6	ser180leu	ser180leu	PROPN
cord-301856-71syce4n	99	7	snp	snp	PROPN
cord-301856-71syce4n	99	8	is	be	AUX
cord-301856-71syce4n	99	9	protective	protective	ADJ
cord-301856-71syce4n	99	10	against	against	ADP
cord-301856-71syce4n	99	11	invasive	invasive	ADJ
cord-301856-71syce4n	99	12	pneumococcal	pneumococcal	ADJ
cord-301856-71syce4n	99	13	disease	disease	NOUN
cord-301856-71syce4n	99	14	,	,	PUNCT
cord-301856-71syce4n	99	15	bacteremia	bacteremia	NOUN
cord-301856-71syce4n	99	16	,	,	PUNCT
cord-301856-71syce4n	99	17	malaria	malaria	NOUN
cord-301856-71syce4n	99	18	,	,	PUNCT
cord-301856-71syce4n	99	19	and	and	CCONJ
cord-301856-71syce4n	99	20	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	99	21	,	,	PUNCT
cord-301856-71syce4n	99	22	as	as	SCONJ
cord-301856-71syce4n	99	23	shown	show	VERB
cord-301856-71syce4n	99	24	in	in	ADP
cord-301856-71syce4n	99	25	a	a	DET
cord-301856-71syce4n	99	26	case	case	NOUN
cord-301856-71syce4n	99	27	-	-	PUNCT
cord-301856-71syce4n	99	28	control	control	NOUN
cord-301856-71syce4n	99	29	study	study	NOUN
cord-301856-71syce4n	99	30	of	of	ADP
cord-301856-71syce4n	99	31	6106	6106	NUM
cord-301856-71syce4n	99	32	individuals	individual	NOUN
cord-301856-71syce4n	99	33	from	from	ADP
cord-301856-71syce4n	99	34	the	the	DET
cord-301856-71syce4n	99	35	uk	uk	PROPN
cord-301856-71syce4n	99	36	,	,	PUNCT
cord-301856-71syce4n	99	37	vietnam	vietnam	PROPN
cord-301856-71syce4n	99	38	,	,	PUNCT
cord-301856-71syce4n	99	39	and	and	CCONJ
cord-301856-71syce4n	99	40	several	several	ADJ
cord-301856-71syce4n	99	41	african	african	ADJ
cord-301856-71syce4n	99	42	countries	country	NOUN
cord-301856-71syce4n	99	43	,	,	PUNCT
cord-301856-71syce4n	99	44	and	and	CCONJ
cord-301856-71syce4n	99	45	it	it	PRON
cord-301856-71syce4n	99	46	is	be	AUX
cord-301856-71syce4n	99	47	associated	associate	VERB
cord-301856-71syce4n	99	48	with	with	ADP
cord-301856-71syce4n	99	49	lower	low	ADJ
cord-301856-71syce4n	99	50	tlr2	tlr2	PROPN
cord-301856-71syce4n	99	51	signaling	signal	VERB
cord-301856-71syce4n	99	52	in	in	ADP
cord-301856-71syce4n	99	53	humans	human	NOUN
cord-301856-71syce4n	100	1	[	[	X
cord-301856-71syce4n	100	2	36	36	NUM
cord-301856-71syce4n	100	3	]	]	PUNCT
cord-301856-71syce4n	100	4	.	.	PUNCT
cord-301856-71syce4n	101	1	this	this	DET
cord-301856-71syce4n	101	2	variant	variant	NOUN
cord-301856-71syce4n	101	3	is	be	AUX
cord-301856-71syce4n	101	4	considered	consider	VERB
cord-301856-71syce4n	101	5	to	to	PART
cord-301856-71syce4n	101	6	be	be	AUX
cord-301856-71syce4n	101	7	a	a	DET
cord-301856-71syce4n	101	8	consequence	consequence	NOUN
cord-301856-71syce4n	101	9	of	of	ADP
cord-301856-71syce4n	101	10	the	the	DET
cord-301856-71syce4n	101	11	natural	natural	ADJ
cord-301856-71syce4n	101	12	selection	selection	NOUN
cord-301856-71syce4n	101	13	that	that	PRON
cord-301856-71syce4n	101	14	may	may	AUX
cord-301856-71syce4n	101	15	have	have	AUX
cord-301856-71syce4n	101	16	taken	take	VERB
cord-301856-71syce4n	101	17	place	place	NOUN
cord-301856-71syce4n	101	18	in	in	ADP
cord-301856-71syce4n	101	19	an	an	DET
cord-301856-71syce4n	101	20	early	early	ADJ
cord-301856-71syce4n	101	21	period	period	NOUN
cord-301856-71syce4n	101	22	following	follow	VERB
cord-301856-71syce4n	101	23	the	the	DET
cord-301856-71syce4n	101	24	migration	migration	NOUN
cord-301856-71syce4n	101	25	of	of	ADP
cord-301856-71syce4n	101	26	modern	modern	ADJ
cord-301856-71syce4n	101	27	humans	human	NOUN
cord-301856-71syce4n	101	28	out	out	ADP
cord-301856-71syce4n	101	29	of	of	ADP
cord-301856-71syce4n	101	30	africa	africa	PROPN
cord-301856-71syce4n	102	1	[	[	PUNCT
cord-301856-71syce4n	102	2	37	37	NUM
cord-301856-71syce4n	102	3	]	]	PUNCT
cord-301856-71syce4n	102	4	.	.	PUNCT
cord-301856-71syce4n	103	1	european	european	ADJ
cord-301856-71syce4n	103	2	populations	population	NOUN
cord-301856-71syce4n	103	3	present	present	VERB
cord-301856-71syce4n	103	4	a	a	DET
cord-301856-71syce4n	103	5	selective	selective	ADJ
cord-301856-71syce4n	103	6	adaptation	adaptation	NOUN
cord-301856-71syce4n	103	7	of	of	ADP
cord-301856-71syce4n	103	8	the	the	DET
cord-301856-71syce4n	103	9	ifn	ifn	ADJ
cord-301856-71syce4n	103	10	gene	gene	NOUN
cord-301856-71syce4n	103	11	that	that	PRON
cord-301856-71syce4n	103	12	allows	allow	VERB
cord-301856-71syce4n	103	13	a	a	DET
cord-301856-71syce4n	103	14	high	high	ADJ
cord-301856-71syce4n	103	15	production	production	NOUN
cord-301856-71syce4n	103	16	of	of	ADP
cord-301856-71syce4n	103	17	ifn	ifn	PROPN
cord-301856-71syce4n	103	18	-	-	PUNCT
cord-301856-71syce4n	103	19	g	g	NOUN
cord-301856-71syce4n	103	20	in	in	ADP
cord-301856-71syce4n	103	21	infectious	infectious	ADJ
cord-301856-71syce4n	103	22	scenarios	scenario	NOUN
cord-301856-71syce4n	103	23	due	due	ADP
cord-301856-71syce4n	103	24	to	to	ADP
cord-301856-71syce4n	103	25	the	the	DET
cord-301856-71syce4n	103	26	positive	positive	ADJ
cord-301856-71syce4n	103	27	selection	selection	NOUN
cord-301856-71syce4n	103	28	of	of	ADP
cord-301856-71syce4n	103	29	ifng	ifng	ADJ
cord-301856-71syce4n	103	30	variants	variant	NOUN
cord-301856-71syce4n	103	31	+5173	+5173	PROPN
cord-301856-71syce4n	103	32	g	g	NOUN
cord-301856-71syce4n	103	33	and	and	CCONJ
cord-301856-71syce4n	103	34	+874	+874	PROPN
cord-301856-71syce4n	103	35	t	t	PROPN
cord-301856-71syce4n	103	36	;	;	PUNCT
cord-301856-71syce4n	103	37	this	this	PRON
cord-301856-71syce4n	103	38	suggests	suggest	VERB
cord-301856-71syce4n	103	39	the	the	DET
cord-301856-71syce4n	103	40	existence	existence	NOUN
cord-301856-71syce4n	103	41	of	of	ADP
cord-301856-71syce4n	103	42	strong	strong	ADJ
cord-301856-71syce4n	103	43	environmental	environmental	ADJ
cord-301856-71syce4n	103	44	pressures	pressure	NOUN
cord-301856-71syce4n	103	45	linked	link	VERB
cord-301856-71syce4n	103	46	to	to	ADP
cord-301856-71syce4n	103	47	higher	high	ADJ
cord-301856-71syce4n	103	48	ifn	ifn	NOUN
cord-301856-71syce4n	103	49	-	-	PUNCT
cord-301856-71syce4n	103	50	g	g	NOUN
cord-301856-71syce4n	103	51	concentrations	concentration	NOUN
cord-301856-71syce4n	103	52	in	in	ADP
cord-301856-71syce4n	103	53	plasma	plasma	NOUN
cord-301856-71syce4n	103	54	during	during	ADP
cord-301856-71syce4n	103	55	mtb	mtb	NOUN
cord-301856-71syce4n	103	56	infection	infection	NOUN
cord-301856-71syce4n	103	57	in	in	ADP
cord-301856-71syce4n	103	58	european	european	ADJ
cord-301856-71syce4n	103	59	individuals	individual	NOUN
cord-301856-71syce4n	103	60	relative	relative	ADJ
cord-301856-71syce4n	103	61	to	to	ADP
cord-301856-71syce4n	103	62	other	other	ADJ
cord-301856-71syce4n	103	63	populations	population	NOUN
cord-301856-71syce4n	103	64	[	[	PUNCT
cord-301856-71syce4n	103	65	38	38	NUM
cord-301856-71syce4n	103	66	,	,	PUNCT
cord-301856-71syce4n	103	67	39	39	NUM
cord-301856-71syce4n	103	68	]	]	PUNCT
cord-301856-71syce4n	103	69	.	.	PUNCT
cord-301856-71syce4n	104	1	in	in	ADP
cord-301856-71syce4n	104	2	line	line	NOUN
cord-301856-71syce4n	104	3	with	with	ADP
cord-301856-71syce4n	104	4	this	this	PRON
cord-301856-71syce4n	104	5	,	,	PUNCT
cord-301856-71syce4n	104	6	a	a	DET
cord-301856-71syce4n	104	7	database	database	NOUN
cord-301856-71syce4n	104	8	meta	meta	NOUN
cord-301856-71syce4n	104	9	-	-	PUNCT
cord-301856-71syce4n	104	10	analysis	analysis	NOUN
cord-301856-71syce4n	104	11	showed	show	VERB
cord-301856-71syce4n	104	12	that	that	SCONJ
cord-301856-71syce4n	104	13	individuals	individual	NOUN
cord-301856-71syce4n	104	14	expressing	express	VERB
cord-301856-71syce4n	104	15	the	the	DET
cord-301856-71syce4n	104	16	+874t	+874t	PROPN
cord-301856-71syce4n	104	17	/	/	SYM
cord-301856-71syce4n	104	18	a	a	DET
cord-301856-71syce4n	104	19	variant	variant	NOUN
cord-301856-71syce4n	104	20	of	of	ADP
cord-301856-71syce4n	104	21	ifng	ifng	PROPN
cord-301856-71syce4n	104	22	presented	present	VERB
cord-301856-71syce4n	104	23	higher	high	ADJ
cord-301856-71syce4n	104	24	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	104	25	to	to	ADP
cord-301856-71syce4n	104	26	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	104	27	mtb	mtb	NOUN
cord-301856-71syce4n	104	28	infection	infection	NOUN
cord-301856-71syce4n	104	29	than	than	ADP
cord-301856-71syce4n	104	30	individuals	individual	NOUN
cord-301856-71syce4n	104	31	without	without	ADP
cord-301856-71syce4n	104	32	it	it	PRON
cord-301856-71syce4n	104	33	,	,	PUNCT
cord-301856-71syce4n	104	34	which	which	PRON
cord-301856-71syce4n	104	35	might	might	AUX
cord-301856-71syce4n	104	36	be	be	AUX
cord-301856-71syce4n	104	37	considered	consider	VERB
cord-301856-71syce4n	104	38	a	a	DET
cord-301856-71syce4n	104	39	putative	putative	ADJ
cord-301856-71syce4n	104	40	prognostic	prognostic	ADJ
cord-301856-71syce4n	104	41	factor	factor	NOUN
cord-301856-71syce4n	104	42	for	for	ADP
cord-301856-71syce4n	104	43	the	the	DET
cord-301856-71syce4n	104	44	development	development	NOUN
cord-301856-71syce4n	104	45	of	of	ADP
cord-301856-71syce4n	104	46	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	105	1	[	[	X
cord-301856-71syce4n	105	2	40	40	NUM
cord-301856-71syce4n	105	3	]	]	PUNCT
cord-301856-71syce4n	105	4	,	,	PUNCT
cord-301856-71syce4n	105	5	although	although	SCONJ
cord-301856-71syce4n	105	6	this	this	PRON
cord-301856-71syce4n	105	7	remains	remain	VERB
cord-301856-71syce4n	105	8	to	to	PART
cord-301856-71syce4n	105	9	be	be	AUX
cord-301856-71syce4n	105	10	robustly	robustly	ADV
cord-301856-71syce4n	105	11	demonstrated	demonstrate	VERB
cord-301856-71syce4n	105	12	.	.	PUNCT
cord-301856-71syce4n	106	1	one	one	NUM
cord-301856-71syce4n	106	2	of	of	ADP
cord-301856-71syce4n	106	3	the	the	DET
cord-301856-71syce4n	106	4	most	most	ADV
cord-301856-71syce4n	106	5	interesting	interesting	ADJ
cord-301856-71syce4n	106	6	aspects	aspect	NOUN
cord-301856-71syce4n	106	7	of	of	ADP
cord-301856-71syce4n	106	8	humans	human	NOUN
cord-301856-71syce4n	106	9	is	be	AUX
cord-301856-71syce4n	106	10	their	their	PRON
cord-301856-71syce4n	106	11	ability	ability	NOUN
cord-301856-71syce4n	106	12	to	to	PART
cord-301856-71syce4n	106	13	adapt	adapt	VERB
cord-301856-71syce4n	106	14	to	to	ADP
cord-301856-71syce4n	106	15	almost	almost	ADV
cord-301856-71syce4n	106	16	every	every	PRON
cord-301856-71syce4n	106	17	ecosystem	ecosystem	NOUN
cord-301856-71syce4n	106	18	of	of	ADP
cord-301856-71syce4n	106	19	the	the	DET
cord-301856-71syce4n	106	20	planet	planet	NOUN
cord-301856-71syce4n	106	21	.	.	PUNCT
cord-301856-71syce4n	107	1	the	the	DET
cord-301856-71syce4n	107	2	history	history	NOUN
cord-301856-71syce4n	107	3	of	of	ADP
cord-301856-71syce4n	107	4	mankind	mankind	NOUN
cord-301856-71syce4n	107	5	is	be	AUX
cord-301856-71syce4n	107	6	also	also	ADV
cord-301856-71syce4n	107	7	the	the	DET
cord-301856-71syce4n	107	8	history	history	NOUN
cord-301856-71syce4n	107	9	of	of	ADP
cord-301856-71syce4n	107	10	millions	million	NOUN
cord-301856-71syce4n	107	11	of	of	ADP
cord-301856-71syce4n	107	12	individuals	individual	NOUN
cord-301856-71syce4n	107	13	wandering	wander	VERB
cord-301856-71syce4n	107	14	around	around	ADP
cord-301856-71syce4n	107	15	the	the	DET
cord-301856-71syce4n	107	16	world	world	NOUN
cord-301856-71syce4n	107	17	,	,	PUNCT
cord-301856-71syce4n	107	18	looking	look	VERB
cord-301856-71syce4n	107	19	for	for	ADP
cord-301856-71syce4n	107	20	a	a	DET
cord-301856-71syce4n	107	21	better	well	ADJ
cord-301856-71syce4n	107	22	place	place	NOUN
cord-301856-71syce4n	107	23	to	to	PART
cord-301856-71syce4n	107	24	live	live	VERB
cord-301856-71syce4n	107	25	.	.	PUNCT
cord-301856-71syce4n	108	1	a	a	DET
cord-301856-71syce4n	108	2	glimpse	glimpse	NOUN
cord-301856-71syce4n	108	3	to	to	ADP
cord-301856-71syce4n	108	4	the	the	DET
cord-301856-71syce4n	108	5	migratory	migratory	ADJ
cord-301856-71syce4n	108	6	legacy	legacy	NOUN
cord-301856-71syce4n	108	7	of	of	ADP
cord-301856-71syce4n	108	8	humanity	humanity	NOUN
cord-301856-71syce4n	108	9	around	around	ADP
cord-301856-71syce4n	108	10	the	the	DET
cord-301856-71syce4n	108	11	globe	globe	NOUN
cord-301856-71syce4n	108	12	reveals	reveal	VERB
cord-301856-71syce4n	108	13	the	the	DET
cord-301856-71syce4n	108	14	great	great	ADJ
cord-301856-71syce4n	108	15	impact	impact	NOUN
cord-301856-71syce4n	108	16	that	that	SCONJ
cord-301856-71syce4n	108	17	the	the	DET
cord-301856-71syce4n	108	18	massive	massive	ADJ
cord-301856-71syce4n	108	19	population	population	NOUN
cord-301856-71syce4n	108	20	movements	movement	NOUN
cord-301856-71syce4n	108	21	defined	define	VERB
cord-301856-71syce4n	108	22	the	the	DET
cord-301856-71syce4n	108	23	world	world	NOUN
cord-301856-71syce4n	108	24	as	as	SCONJ
cord-301856-71syce4n	108	25	we	we	PRON
cord-301856-71syce4n	108	26	know	know	VERB
cord-301856-71syce4n	108	27	it	it	PRON
cord-301856-71syce4n	108	28	today	today	NOUN
cord-301856-71syce4n	108	29	(	(	PUNCT
cord-301856-71syce4n	108	30	see	see	VERB
cord-301856-71syce4n	108	31	figure	figure	NOUN
cord-301856-71syce4n	108	32	3	3	NUM
cord-301856-71syce4n	108	33	in	in	ADP
cord-301856-71syce4n	108	34	main	main	ADJ
cord-301856-71syce4n	108	35	text	text	NOUN
cord-301856-71syce4n	108	36	)	)	PUNCT
cord-301856-71syce4n	108	37	.	.	PUNCT
cord-301856-71syce4n	109	1	the	the	DET
cord-301856-71syce4n	109	2	distances	distance	NOUN
cord-301856-71syce4n	109	3	ancient	ancient	ADJ
cord-301856-71syce4n	109	4	humans	human	NOUN
cord-301856-71syce4n	109	5	travelled	travel	VERB
cord-301856-71syce4n	109	6	are	be	AUX
cord-301856-71syce4n	109	7	impressive	impressive	ADJ
cord-301856-71syce4n	109	8	,	,	PUNCT
cord-301856-71syce4n	109	9	from	from	ADP
cord-301856-71syce4n	109	10	the	the	DET
cord-301856-71syce4n	109	11	first	first	ADJ
cord-301856-71syce4n	109	12	hominids	hominid	NOUN
cord-301856-71syce4n	109	13	colonizing	colonizing	PROPN
cord-301856-71syce4n	109	14	africa	africa	PROPN
cord-301856-71syce4n	109	15	to	to	ADP
cord-301856-71syce4n	109	16	the	the	DET
cord-301856-71syce4n	109	17	conquest	conquest	NOUN
cord-301856-71syce4n	109	18	of	of	ADP
cord-301856-71syce4n	109	19	the	the	DET
cord-301856-71syce4n	109	20	americas	america	NOUN
cord-301856-71syce4n	109	21	in	in	ADP
cord-301856-71syce4n	109	22	a	a	DET
cord-301856-71syce4n	109	23	time	time	NOUN
cord-301856-71syce4n	109	24	when	when	SCONJ
cord-301856-71syce4n	109	25	the	the	DET
cord-301856-71syce4n	109	26	bering	bering	NOUN
cord-301856-71syce4n	109	27	strait	strait	NOUN
cord-301856-71syce4n	109	28	was	be	AUX
cord-301856-71syce4n	109	29	not	not	PART
cord-301856-71syce4n	109	30	yet	yet	ADV
cord-301856-71syce4n	109	31	under	under	ADP
cord-301856-71syce4n	109	32	water	water	NOUN
cord-301856-71syce4n	109	33	.	.	PUNCT
cord-301856-71syce4n	110	1	the	the	DET
cord-301856-71syce4n	110	2	historical	historical	ADJ
cord-301856-71syce4n	110	3	exodus	exodus	NOUN
cord-301856-71syce4n	110	4	of	of	ADP
cord-301856-71syce4n	110	5	mankind	mankind	NOUN
cord-301856-71syce4n	110	6	started	start	VERB
cord-301856-71syce4n	110	7	almost	almost	ADV
cord-301856-71syce4n	110	8	2	2	NUM
cord-301856-71syce4n	110	9	million	million	NUM
cord-301856-71syce4n	110	10	years	year	NOUN
cord-301856-71syce4n	110	11	ago	ago	ADV
cord-301856-71syce4n	110	12	with	with	ADP
cord-301856-71syce4n	110	13	the	the	DET
cord-301856-71syce4n	110	14	migration	migration	NOUN
cord-301856-71syce4n	110	15	of	of	ADP
cord-301856-71syce4n	110	16	homo	homo	ADJ
cord-301856-71syce4n	110	17	erectus	erectus	PROPN
cord-301856-71syce4n	110	18	from	from	ADP
cord-301856-71syce4n	110	19	africa	africa	PROPN
cord-301856-71syce4n	110	20	through	through	ADP
cord-301856-71syce4n	110	21	eurasia	eurasia	PROPN
cord-301856-71syce4n	110	22	.	.	PUNCT
cord-301856-71syce4n	111	1	from	from	ADP
cord-301856-71syce4n	111	2	this	this	DET
cord-301856-71syce4n	111	3	event	event	NOUN
cord-301856-71syce4n	111	4	on	on	ADP
cord-301856-71syce4n	111	5	,	,	PUNCT
cord-301856-71syce4n	111	6	relatively	relatively	ADV
cord-301856-71syce4n	111	7	isolated	isolated	ADJ
cord-301856-71syce4n	111	8	human	human	ADJ
cord-301856-71syce4n	111	9	populations	population	NOUN
cord-301856-71syce4n	111	10	evolved	evolve	VERB
cord-301856-71syce4n	111	11	separately	separately	ADV
cord-301856-71syce4n	111	12	on	on	ADP
cord-301856-71syce4n	111	13	different	different	ADJ
cord-301856-71syce4n	111	14	continents	continent	NOUN
cord-301856-71syce4n	111	15	,	,	PUNCT
cord-301856-71syce4n	111	16	leading	lead	VERB
cord-301856-71syce4n	111	17	to	to	ADP
cord-301856-71syce4n	111	18	the	the	DET
cord-301856-71syce4n	111	19	emergence	emergence	NOUN
cord-301856-71syce4n	111	20	of	of	ADP
cord-301856-71syce4n	111	21	different	different	ADJ
cord-301856-71syce4n	111	22	human	human	ADJ
cord-301856-71syce4n	111	23	species	specie	NOUN
cord-301856-71syce4n	111	24	,	,	PUNCT
cord-301856-71syce4n	111	25	such	such	ADJ
cord-301856-71syce4n	111	26	as	as	ADP
cord-301856-71syce4n	111	27	neanderthals	neanderthal	NOUN
cord-301856-71syce4n	111	28	in	in	ADP
cord-301856-71syce4n	111	29	europe	europe	PROPN
cord-301856-71syce4n	111	30	,	,	PUNCT
cord-301856-71syce4n	111	31	the	the	DET
cord-301856-71syce4n	111	32	denisovans	denisovan	NOUN
cord-301856-71syce4n	111	33	in	in	ADP
cord-301856-71syce4n	111	34	asia	asia	PROPN
cord-301856-71syce4n	111	35	,	,	PUNCT
cord-301856-71syce4n	111	36	and	and	CCONJ
cord-301856-71syce4n	111	37	,	,	PUNCT
cord-301856-71syce4n	111	38	later	later	ADV
cord-301856-71syce4n	111	39	,	,	PUNCT
cord-301856-71syce4n	111	40	modern	modern	ADJ
cord-301856-71syce4n	111	41	homo	homo	ADJ
cord-301856-71syce4n	111	42	sapiens	sapiens	PROPN
cord-301856-71syce4n	111	43	in	in	ADP
cord-301856-71syce4n	111	44	africa	africa	PROPN
cord-301856-71syce4n	112	1	[	[	PUNCT
cord-301856-71syce4n	112	2	92	92	NUM
cord-301856-71syce4n	112	3	,	,	PUNCT
cord-301856-71syce4n	112	4	93	93	NUM
cord-301856-71syce4n	112	5	]	]	PUNCT
cord-301856-71syce4n	112	6	.	.	PUNCT
cord-301856-71syce4n	113	1	h.	h.	PROPN
cord-301856-71syce4n	114	1	sapiens	sapiens	PROPN
cord-301856-71syce4n	114	2	first	first	ADV
cord-301856-71syce4n	114	3	colonized	colonize	VERB
cord-301856-71syce4n	114	4	large	large	ADJ
cord-301856-71syce4n	114	5	areas	area	NOUN
cord-301856-71syce4n	114	6	of	of	ADP
cord-301856-71syce4n	114	7	the	the	DET
cord-301856-71syce4n	114	8	continent	continent	NOUN
cord-301856-71syce4n	114	9	around	around	ADP
cord-301856-71syce4n	114	10	300	300	NUM
cord-301856-71syce4n	114	11	000	000	NUM
cord-301856-71syce4n	114	12	years	year	NOUN
cord-301856-71syce4n	114	13	ago	ago	ADV
cord-301856-71syce4n	114	14	[	[	X
cord-301856-71syce4n	114	15	6	6	NUM
cord-301856-71syce4n	114	16	]	]	PUNCT
cord-301856-71syce4n	114	17	,	,	PUNCT
cord-301856-71syce4n	114	18	spread	spread	VERB
cord-301856-71syce4n	114	19	towards	towards	ADP
cord-301856-71syce4n	114	20	the	the	DET
cord-301856-71syce4n	114	21	middle	middle	PROPN
cord-301856-71syce4n	114	22	east	east	PROPN
cord-301856-71syce4n	114	23	at	at	ADP
cord-301856-71syce4n	114	24	some	some	DET
cord-301856-71syce4n	114	25	point	point	NOUN
cord-301856-71syce4n	114	26	between	between	ADP
cord-301856-71syce4n	114	27	150	150	NUM
cord-301856-71syce4n	114	28	000	000	NUM
cord-301856-71syce4n	114	29	and	and	CCONJ
cord-301856-71syce4n	114	30	80	80	NUM
cord-301856-71syce4n	114	31	000	000	NUM
cord-301856-71syce4n	114	32	years	year	NOUN
cord-301856-71syce4n	114	33	ago	ago	ADV
cord-301856-71syce4n	114	34	,	,	PUNCT
cord-301856-71syce4n	114	35	and	and	CCONJ
cord-301856-71syce4n	114	36	migrated	migrate	VERB
cord-301856-71syce4n	114	37	through	through	ADP
cord-301856-71syce4n	114	38	eurasia	eurasia	PROPN
cord-301856-71syce4n	114	39	,	,	PUNCT
cord-301856-71syce4n	114	40	reaching	reach	VERB
cord-301856-71syce4n	114	41	australia	australia	PROPN
cord-301856-71syce4n	114	42	within	within	ADP
cord-301856-71syce4n	114	43	20	20	NUM
cord-301856-71syce4n	114	44	000	000	NUM
cord-301856-71syce4n	114	45	years	year	NOUN
cord-301856-71syce4n	114	46	[	[	X
cord-301856-71syce4n	114	47	94	94	NUM
cord-301856-71syce4n	114	48	]	]	PUNCT
cord-301856-71syce4n	114	49	.	.	PUNCT
cord-301856-71syce4n	115	1	asian	asian	PROPN
cord-301856-71syce4n	115	2	human	human	PROPN
cord-301856-71syce4n	115	3	ancestors	ancestor	NOUN
cord-301856-71syce4n	115	4	went	go	VERB
cord-301856-71syce4n	115	5	through	through	ADP
cord-301856-71syce4n	115	6	the	the	DET
cord-301856-71syce4n	115	7	frozen	frozen	ADJ
cord-301856-71syce4n	115	8	waters	water	NOUN
cord-301856-71syce4n	115	9	of	of	ADP
cord-301856-71syce4n	115	10	the	the	DET
cord-301856-71syce4n	115	11	bering	bering	NOUN
cord-301856-71syce4n	115	12	strait	strait	NOUN
cord-301856-71syce4n	115	13	in	in	ADP
cord-301856-71syce4n	115	14	two	two	NUM
cord-301856-71syce4n	115	15	distinct	distinct	ADJ
cord-301856-71syce4n	115	16	waves	wave	NOUN
cord-301856-71syce4n	115	17	to	to	PART
cord-301856-71syce4n	115	18	colonize	colonize	VERB
cord-301856-71syce4n	115	19	the	the	DET
cord-301856-71syce4n	115	20	american	american	PROPN
cord-301856-71syce4n	115	21	continent	continent	PROPN
cord-301856-71syce4n	115	22	approximately	approximately	ADV
cord-301856-71syce4n	115	23	20	20	NUM
cord-301856-71syce4n	115	24	000	000	NUM
cord-301856-71syce4n	115	25	years	year	NOUN
cord-301856-71syce4n	115	26	before	before	ADP
cord-301856-71syce4n	115	27	the	the	DET
cord-301856-71syce4n	115	28	present	present	ADJ
cord-301856-71syce4n	115	29	time	time	NOUN
cord-301856-71syce4n	115	30	[	[	X
cord-301856-71syce4n	115	31	95	95	NUM
cord-301856-71syce4n	115	32	]	]	PUNCT
cord-301856-71syce4n	115	33	.	.	PUNCT
cord-301856-71syce4n	116	1	when	when	SCONJ
cord-301856-71syce4n	116	2	humans	human	NOUN
cord-301856-71syce4n	116	3	ventured	venture	VERB
cord-301856-71syce4n	116	4	out	out	ADP
cord-301856-71syce4n	116	5	of	of	ADP
cord-301856-71syce4n	116	6	africa	africa	PROPN
cord-301856-71syce4n	116	7	,	,	PUNCT
cord-301856-71syce4n	116	8	they	they	PRON
cord-301856-71syce4n	116	9	faced	face	VERB
cord-301856-71syce4n	116	10	different	different	ADJ
cord-301856-71syce4n	116	11	types	type	NOUN
cord-301856-71syce4n	116	12	of	of	ADP
cord-301856-71syce4n	116	13	pathogens	pathogen	NOUN
cord-301856-71syce4n	116	14	than	than	ADP
cord-301856-71syce4n	116	15	the	the	DET
cord-301856-71syce4n	116	16	communities	community	NOUN
cord-301856-71syce4n	116	17	that	that	PRON
cord-301856-71syce4n	116	18	stayed	stay	VERB
cord-301856-71syce4n	116	19	in	in	ADP
cord-301856-71syce4n	116	20	the	the	DET
cord-301856-71syce4n	116	21	african	african	ADJ
cord-301856-71syce4n	116	22	continent	continent	NOUN
cord-301856-71syce4n	116	23	.	.	PUNCT
cord-301856-71syce4n	117	1	with	with	ADP
cord-301856-71syce4n	117	2	time	time	NOUN
cord-301856-71syce4n	117	3	,	,	PUNCT
cord-301856-71syce4n	117	4	the	the	DET
cord-301856-71syce4n	117	5	series	series	NOUN
cord-301856-71syce4n	117	6	of	of	ADP
cord-301856-71syce4n	117	7	events	event	NOUN
cord-301856-71syce4n	117	8	faced	face	VERB
cord-301856-71syce4n	117	9	by	by	ADP
cord-301856-71syce4n	117	10	diverse	diverse	ADJ
cord-301856-71syce4n	117	11	populations	population	NOUN
cord-301856-71syce4n	117	12	has	have	AUX
cord-301856-71syce4n	117	13	generated	generate	VERB
cord-301856-71syce4n	117	14	differences	difference	NOUN
cord-301856-71syce4n	117	15	in	in	ADP
cord-301856-71syce4n	117	16	the	the	DET
cord-301856-71syce4n	117	17	immune	immune	ADJ
cord-301856-71syce4n	117	18	responses	response	NOUN
cord-301856-71syce4n	117	19	to	to	ADP
cord-301856-71syce4n	117	20	pathogens	pathogen	NOUN
cord-301856-71syce4n	117	21	in	in	ADP
cord-301856-71syce4n	117	22	the	the	DET
cord-301856-71syce4n	117	23	populations	population	NOUN
cord-301856-71syce4n	117	24	with	with	ADP
cord-301856-71syce4n	117	25	an	an	DET
cord-301856-71syce4n	117	26	african	african	ADJ
cord-301856-71syce4n	117	27	or	or	CCONJ
cord-301856-71syce4n	117	28	eurasian	eurasian	ADJ
cord-301856-71syce4n	117	29	origin	origin	NOUN
cord-301856-71syce4n	117	30	and	and	CCONJ
cord-301856-71syce4n	117	31	which	which	PRON
cord-301856-71syce4n	117	32	have	have	AUX
cord-301856-71syce4n	117	33	spread	spread	VERB
cord-301856-71syce4n	117	34	throughout	throughout	ADP
cord-301856-71syce4n	117	35	the	the	DET
cord-301856-71syce4n	117	36	world	world	NOUN
cord-301856-71syce4n	117	37	.	.	PUNCT
cord-301856-71syce4n	118	1	the	the	DET
cord-301856-71syce4n	118	2	indigenous	indigenous	ADJ
cord-301856-71syce4n	118	3	populations	population	NOUN
cord-301856-71syce4n	118	4	of	of	ADP
cord-301856-71syce4n	118	5	south	south	PROPN
cord-301856-71syce4n	118	6	america	america	PROPN
cord-301856-71syce4n	118	7	are	be	AUX
cord-301856-71syce4n	118	8	descendants	descendant	NOUN
cord-301856-71syce4n	118	9	of	of	ADP
cord-301856-71syce4n	118	10	migrating	migrating	NOUN
cord-301856-71syce4n	118	11	populations	population	NOUN
cord-301856-71syce4n	118	12	of	of	ADP
cord-301856-71syce4n	118	13	north	north	NOUN
cord-301856-71syce4n	118	14	-	-	PUNCT
cord-301856-71syce4n	118	15	east	east	NOUN
cord-301856-71syce4n	118	16	asians	asians	PROPN
cord-301856-71syce4n	118	17	that	that	PRON
cord-301856-71syce4n	118	18	crossed	cross	VERB
cord-301856-71syce4n	118	19	the	the	DET
cord-301856-71syce4n	118	20	bering	bering	NOUN
cord-301856-71syce4n	118	21	strait	strait	NOUN
cord-301856-71syce4n	118	22	around	around	ADP
cord-301856-71syce4n	118	23	20	20	NUM
cord-301856-71syce4n	118	24	000	000	NUM
cord-301856-71syce4n	118	25	years	year	NOUN
cord-301856-71syce4n	118	26	ago	ago	ADV
cord-301856-71syce4n	118	27	[	[	X
cord-301856-71syce4n	118	28	41	41	NUM
cord-301856-71syce4n	118	29	]	]	PUNCT
cord-301856-71syce4n	118	30	.	.	PUNCT
cord-301856-71syce4n	119	1	five	five	NUM
cord-301856-71syce4n	119	2	centuries	century	NOUN
cord-301856-71syce4n	119	3	ago	ago	ADV
cord-301856-71syce4n	119	4	,	,	PUNCT
cord-301856-71syce4n	119	5	european	european	ADJ
cord-301856-71syce4n	119	6	settlers	settler	NOUN
cord-301856-71syce4n	119	7	disembarked	disembark	VERB
cord-301856-71syce4n	119	8	on	on	ADP
cord-301856-71syce4n	119	9	the	the	DET
cord-301856-71syce4n	119	10	american	american	ADJ
cord-301856-71syce4n	119	11	continent	continent	NOUN
cord-301856-71syce4n	119	12	,	,	PUNCT
cord-301856-71syce4n	119	13	bringing	bring	VERB
cord-301856-71syce4n	119	14	a	a	DET
cord-301856-71syce4n	119	15	large	large	ADJ
cord-301856-71syce4n	119	16	collection	collection	NOUN
cord-301856-71syce4n	119	17	of	of	ADP
cord-301856-71syce4n	119	18	pathogens	pathogen	NOUN
cord-301856-71syce4n	119	19	such	such	ADJ
cord-301856-71syce4n	119	20	as	as	ADP
cord-301856-71syce4n	119	21	those	those	PRON
cord-301856-71syce4n	119	22	causing	cause	VERB
cord-301856-71syce4n	119	23	measles	measle	NOUN
cord-301856-71syce4n	119	24	,	,	PUNCT
cord-301856-71syce4n	119	25	pneumonic	pneumonic	PROPN
cord-301856-71syce4n	119	26	plague	plague	NOUN
cord-301856-71syce4n	119	27	,	,	PUNCT
cord-301856-71syce4n	119	28	and	and	CCONJ
cord-301856-71syce4n	119	29	influenza	influenza	NOUN
cord-301856-71syce4n	119	30	infections	infection	NOUN
cord-301856-71syce4n	119	31	,	,	PUNCT
cord-301856-71syce4n	119	32	which	which	PRON
cord-301856-71syce4n	119	33	the	the	DET
cord-301856-71syce4n	119	34	indigenous	indigenous	ADJ
cord-301856-71syce4n	119	35	populations	population	NOUN
cord-301856-71syce4n	119	36	had	have	AUX
cord-301856-71syce4n	119	37	never	never	ADV
cord-301856-71syce4n	119	38	faced	face	VERB
cord-301856-71syce4n	119	39	before	before	ADV
cord-301856-71syce4n	119	40	.	.	PUNCT
cord-301856-71syce4n	120	1	these	these	DET
cord-301856-71syce4n	120	2	diseases	disease	NOUN
cord-301856-71syce4n	120	3	rapidly	rapidly	ADV
cord-301856-71syce4n	120	4	spread	spread	VERB
cord-301856-71syce4n	120	5	and	and	CCONJ
cord-301856-71syce4n	120	6	caused	cause	VERB
cord-301856-71syce4n	120	7	mortality	mortality	NOUN
cord-301856-71syce4n	120	8	rates	rate	NOUN
cord-301856-71syce4n	120	9	above	above	ADP
cord-301856-71syce4n	120	10	90	90	NUM
cord-301856-71syce4n	120	11	%	%	NOUN
cord-301856-71syce4n	120	12	[	[	PUNCT
cord-301856-71syce4n	120	13	42	42	NUM
cord-301856-71syce4n	120	14	]	]	PUNCT
cord-301856-71syce4n	120	15	.	.	PUNCT
cord-301856-71syce4n	121	1	the	the	DET
cord-301856-71syce4n	121	2	consequences	consequence	NOUN
cord-301856-71syce4n	121	3	of	of	ADP
cord-301856-71syce4n	121	4	these	these	DET
cord-301856-71syce4n	121	5	pandemics	pandemic	NOUN
cord-301856-71syce4n	121	6	are	be	AUX
cord-301856-71syce4n	121	7	still	still	ADV
cord-301856-71syce4n	121	8	visible	visible	ADJ
cord-301856-71syce4n	121	9	in	in	ADP
cord-301856-71syce4n	121	10	current	current	ADJ
cord-301856-71syce4n	121	11	populations	population	NOUN
cord-301856-71syce4n	121	12	;	;	PUNCT
cord-301856-71syce4n	121	13	one	one	NUM
cord-301856-71syce4n	121	14	report	report	NOUN
cord-301856-71syce4n	121	15	studied	study	VERB
cord-301856-71syce4n	121	16	dna	dna	PROPN
cord-301856-71syce4n	121	17	from	from	ADP
cord-301856-71syce4n	121	18	the	the	DET
cord-301856-71syce4n	121	19	bones	bone	NOUN
cord-301856-71syce4n	121	20	of	of	ADP
cord-301856-71syce4n	121	21	25	25	NUM
cord-301856-71syce4n	121	22	ancient	ancient	ADJ
cord-301856-71syce4n	121	23	humans	human	NOUN
cord-301856-71syce4n	121	24	from	from	ADP
cord-301856-71syce4n	121	25	the	the	DET
cord-301856-71syce4n	121	26	tsimshian	tsimshian	ADJ
cord-301856-71syce4n	121	27	community	community	NOUN
cord-301856-71syce4n	121	28	,	,	PUNCT
cord-301856-71syce4n	121	29	living	live	VERB
cord-301856-71syce4n	121	30	in	in	ADP
cord-301856-71syce4n	121	31	the	the	DET
cord-301856-71syce4n	121	32	british	british	PROPN
cord-301856-71syce4n	121	33	columbia	columbia	PROPN
cord-301856-71syce4n	121	34	region	region	PROPN
cord-301856-71syce4n	121	35	in	in	ADP
cord-301856-71syce4n	121	36	canada	canada	PROPN
cord-301856-71syce4n	121	37	until	until	ADP
cord-301856-71syce4n	121	38	the	the	DET
cord-301856-71syce4n	121	39	15th	15th	ADJ
cord-301856-71syce4n	121	40	century	century	NOUN
cord-301856-71syce4n	121	41	,	,	PUNCT
cord-301856-71syce4n	121	42	identifying	identify	VERB
cord-301856-71syce4n	121	43	marks	mark	NOUN
cord-301856-71syce4n	121	44	of	of	ADP
cord-301856-71syce4n	121	45	positive	positive	ADJ
cord-301856-71syce4n	121	46	selection	selection	NOUN
cord-301856-71syce4n	121	47	in	in	ADP
cord-301856-71syce4n	121	48	a	a	DET
cord-301856-71syce4n	121	49	number	number	NOUN
cord-301856-71syce4n	121	50	of	of	ADP
cord-301856-71syce4n	121	51	immune	immune	NOUN
cord-301856-71syce4n	121	52	-	-	PUNCT
cord-301856-71syce4n	121	53	related	relate	VERB
cord-301856-71syce4n	121	54	variants	variant	NOUN
cord-301856-71syce4n	121	55	[	[	X
cord-301856-71syce4n	121	56	43	43	NUM
cord-301856-71syce4n	121	57	]	]	PUNCT
cord-301856-71syce4n	121	58	.	.	PUNCT
cord-301856-71syce4n	122	1	specifically	specifically	ADV
cord-301856-71syce4n	122	2	,	,	PUNCT
cord-301856-71syce4n	122	3	the	the	DET
cord-301856-71syce4n	122	4	hla	hla	PROPN
cord-301856-71syce4n	122	5	-	-	PUNCT
cord-301856-71syce4n	122	6	dqa1	dqa1	NOUN
cord-301856-71syce4n	122	7	variant	variant	NOUN
cord-301856-71syce4n	122	8	was	be	AUX
cord-301856-71syce4n	122	9	present	present	ADJ
cord-301856-71syce4n	122	10	in	in	ADP
cord-301856-71syce4n	122	11	almost	almost	ADV
cord-301856-71syce4n	122	12	the	the	DET
cord-301856-71syce4n	122	13	totality	totality	NOUN
cord-301856-71syce4n	122	14	of	of	ADP
cord-301856-71syce4n	122	15	tsimshian	tsimshian	ADJ
cord-301856-71syce4n	122	16	individuals	individual	NOUN
cord-301856-71syce4n	122	17	,	,	PUNCT
cord-301856-71syce4n	122	18	but	but	CCONJ
cord-301856-71syce4n	122	19	only	only	ADV
cord-301856-71syce4n	122	20	in	in	SCONJ
cord-301856-71syce4n	122	21	one	one	NUM
cord-301856-71syce4n	122	22	third	third	NOUN
cord-301856-71syce4n	122	23	of	of	ADP
cord-301856-71syce4n	122	24	present	present	ADJ
cord-301856-71syce4n	122	25	-	-	PUNCT
cord-301856-71syce4n	122	26	day	day	NOUN
cord-301856-71syce4n	122	27	humans	human	NOUN
cord-301856-71syce4n	122	28	studied	study	VERB
cord-301856-71syce4n	122	29	;	;	PUNCT
cord-301856-71syce4n	122	30	this	this	PRON
cord-301856-71syce4n	122	31	suggested	suggest	VERB
cord-301856-71syce4n	122	32	that	that	SCONJ
cord-301856-71syce4n	122	33	ancient	ancient	ADJ
cord-301856-71syce4n	122	34	american	american	ADJ
cord-301856-71syce4n	122	35	genomes	genome	NOUN
cord-301856-71syce4n	122	36	were	be	AUX
cord-301856-71syce4n	122	37	evolutionarily	evolutionarily	ADV
cord-301856-71syce4n	122	38	selected	select	VERB
cord-301856-71syce4n	122	39	to	to	PART
cord-301856-71syce4n	122	40	respond	respond	VERB
cord-301856-71syce4n	122	41	to	to	ADP
cord-301856-71syce4n	122	42	local	local	ADJ
cord-301856-71syce4n	122	43	diseases	disease	NOUN
cord-301856-71syce4n	122	44	but	but	CCONJ
cord-301856-71syce4n	122	45	not	not	PART
cord-301856-71syce4n	122	46	to	to	PART
cord-301856-71syce4n	122	47	fight	fight	VERB
cord-301856-71syce4n	122	48	against	against	ADP
cord-301856-71syce4n	122	49	pathogens	pathogen	NOUN
cord-301856-71syce4n	122	50	brought	bring	VERB
cord-301856-71syce4n	122	51	by	by	ADP
cord-301856-71syce4n	122	52	the	the	DET
cord-301856-71syce4n	122	53	europeans	europeans	PROPN
cord-301856-71syce4n	122	54	[	[	PUNCT
cord-301856-71syce4n	122	55	43	43	NUM
cord-301856-71syce4n	122	56	]	]	PUNCT
cord-301856-71syce4n	122	57	.	.	PUNCT
cord-301856-71syce4n	123	1	another	another	DET
cord-301856-71syce4n	123	2	study	study	NOUN
cord-301856-71syce4n	123	3	compiled	compile	VERB
cord-301856-71syce4n	123	4	information	information	NOUN
cord-301856-71syce4n	123	5	on	on	ADP
cord-301856-71syce4n	123	6	infectious	infectious	ADJ
cord-301856-71syce4n	123	7	diseases	disease	NOUN
cord-301856-71syce4n	123	8	that	that	PRON
cord-301856-71syce4n	123	9	have	have	AUX
cord-301856-71syce4n	123	10	killed	kill	VERB
cord-301856-71syce4n	123	11	more	more	ADJ
cord-301856-71syce4n	123	12	than	than	ADP
cord-301856-71syce4n	123	13	10	10	NUM
cord-301856-71syce4n	123	14	000	000	NUM
cord-301856-71syce4n	123	15	individuals	individual	NOUN
cord-301856-71syce4n	123	16	among	among	ADP
cord-301856-71syce4n	123	17	59	59	NUM
cord-301856-71syce4n	123	18	indigenous	indigenous	ADJ
cord-301856-71syce4n	123	19	communities	community	NOUN
cord-301856-71syce4n	123	20	of	of	ADP
cord-301856-71syce4n	123	21	the	the	DET
cord-301856-71syce4n	123	22	amazonia	amazonia	NOUN
cord-301856-71syce4n	123	23	in	in	ADP
cord-301856-71syce4n	123	24	the	the	DET
cord-301856-71syce4n	123	25	past	past	ADJ
cord-301856-71syce4n	123	26	two	two	NUM
cord-301856-71syce4n	123	27	centuries	century	NOUN
cord-301856-71syce4n	123	28	,	,	PUNCT
cord-301856-71syce4n	123	29	showing	show	VERB
cord-301856-71syce4n	123	30	that	that	SCONJ
cord-301856-71syce4n	123	31	the	the	DET
cord-301856-71syce4n	123	32	mortality	mortality	NOUN
cord-301856-71syce4n	123	33	rates	rate	NOUN
cord-301856-71syce4n	123	34	and	and	CCONJ
cord-301856-71syce4n	123	35	the	the	DET
cord-301856-71syce4n	123	36	incidence	incidence	NOUN
cord-301856-71syce4n	123	37	of	of	ADP
cord-301856-71syce4n	123	38	infectious	infectious	ADJ
cord-301856-71syce4n	123	39	diseases	disease	NOUN
cord-301856-71syce4n	123	40	rapidly	rapidly	ADV
cord-301856-71syce4n	123	41	decayed	decay	VERB
cord-301856-71syce4n	123	42	within	within	ADP
cord-301856-71syce4n	123	43	the	the	DET
cord-301856-71syce4n	123	44	time	time	NOUN
cord-301856-71syce4n	123	45	following	follow	VERB
cord-301856-71syce4n	123	46	the	the	DET
cord-301856-71syce4n	123	47	first	first	ADJ
cord-301856-71syce4n	123	48	encounter	encounter	NOUN
cord-301856-71syce4n	123	49	with	with	ADP
cord-301856-71syce4n	123	50	the	the	DET
cord-301856-71syce4n	123	51	pathogen	pathogen	PROPN
cord-301856-71syce4n	123	52	,	,	PUNCT
cord-301856-71syce4n	123	53	compatible	compatible	ADJ
cord-301856-71syce4n	123	54	with	with	ADP
cord-301856-71syce4n	123	55	genetic	genetic	ADJ
cord-301856-71syce4n	123	56	adaptation	adaptation	NOUN
cord-301856-71syce4n	123	57	[	[	X
cord-301856-71syce4n	123	58	44	44	NUM
cord-301856-71syce4n	123	59	]	]	PUNCT
cord-301856-71syce4n	123	60	.	.	PUNCT
cord-301856-71syce4n	124	1	european	european	PROPN
cord-301856-71syce4n	124	2	colonizers	colonizer	NOUN
cord-301856-71syce4n	124	3	underwent	undergo	VERB
cord-301856-71syce4n	124	4	purifying	purifying	NOUN
cord-301856-71syce4n	124	5	selection	selection	NOUN
cord-301856-71syce4n	124	6	in	in	ADP
cord-301856-71syce4n	124	7	situations	situation	NOUN
cord-301856-71syce4n	124	8	of	of	ADP
cord-301856-71syce4n	124	9	intense	intense	ADJ
cord-301856-71syce4n	124	10	pressure	pressure	NOUN
cord-301856-71syce4n	124	11	.	.	PUNCT
cord-301856-71syce4n	125	1	such	such	ADJ
cord-301856-71syce4n	125	2	scenarios	scenario	NOUN
cord-301856-71syce4n	125	3	were	be	AUX
cord-301856-71syce4n	125	4	documented	document	VERB
cord-301856-71syce4n	125	5	when	when	SCONJ
cord-301856-71syce4n	125	6	dutch	dutch	ADJ
cord-301856-71syce4n	125	7	colonists	colonist	NOUN
cord-301856-71syce4n	125	8	migrated	migrate	VERB
cord-301856-71syce4n	125	9	to	to	ADP
cord-301856-71syce4n	125	10	surinam	surinam	PROPN
cord-301856-71syce4n	125	11	and	and	CCONJ
cord-301856-71syce4n	125	12	encountered	encounter	VERB
cord-301856-71syce4n	125	13	epidemics	epidemic	NOUN
cord-301856-71syce4n	125	14	of	of	ADP
cord-301856-71syce4n	125	15	yellow	yellow	ADJ
cord-301856-71syce4n	125	16	and	and	CCONJ
cord-301856-71syce4n	125	17	typhoid	typhoid	NOUN
cord-301856-71syce4n	125	18	fever	fever	NOUN
cord-301856-71syce4n	125	19	that	that	PRON
cord-301856-71syce4n	125	20	caused	cause	VERB
cord-301856-71syce4n	125	21	a	a	DET
cord-301856-71syce4n	125	22	60	60	NUM
cord-301856-71syce4n	125	23	%	%	NOUN
cord-301856-71syce4n	125	24	mortality	mortality	NOUN
cord-301856-71syce4n	125	25	rate	rate	NOUN
cord-301856-71syce4n	125	26	among	among	ADP
cord-301856-71syce4n	125	27	settlers	settler	NOUN
cord-301856-71syce4n	125	28	[	[	X
cord-301856-71syce4n	125	29	45	45	NUM
cord-301856-71syce4n	125	30	]	]	PUNCT
cord-301856-71syce4n	125	31	.	.	PUNCT
cord-301856-71syce4n	126	1	variations	variation	NOUN
cord-301856-71syce4n	126	2	in	in	ADP
cord-301856-71syce4n	126	3	the	the	DET
cord-301856-71syce4n	126	4	frequencies	frequency	NOUN
cord-301856-71syce4n	126	5	of	of	ADP
cord-301856-71syce4n	126	6	c3	c3	PROPN
cord-301856-71syce4n	126	7	,	,	PUNCT
cord-301856-71syce4n	126	8	glo	glo	PROPN
cord-301856-71syce4n	126	9	,	,	PUNCT
cord-301856-71syce4n	126	10	and	and	CCONJ
cord-301856-71syce4n	126	11	hla	hla	PROPN
cord-301856-71syce4n	126	12	-	-	PUNCT
cord-301856-71syce4n	126	13	b	b	PROPN
cord-301856-71syce4n	126	14	genes	gene	NOUN
cord-301856-71syce4n	126	15	among	among	ADP
cord-301856-71syce4n	126	16	the	the	DET
cord-301856-71syce4n	126	17	descendants	descendant	NOUN
cord-301856-71syce4n	126	18	were	be	AUX
cord-301856-71syce4n	126	19	not	not	PART
cord-301856-71syce4n	126	20	likely	likely	ADV
cord-301856-71syce4n	126	21	caused	cause	VERB
cord-301856-71syce4n	126	22	by	by	ADP
cord-301856-71syce4n	126	23	genetic	genetic	ADJ
cord-301856-71syce4n	126	24	drift	drift	NOUN
cord-301856-71syce4n	126	25	,	,	PUNCT
cord-301856-71syce4n	126	26	but	but	CCONJ
cord-301856-71syce4n	126	27	rather	rather	ADV
cord-301856-71syce4n	126	28	,	,	PUNCT
cord-301856-71syce4n	126	29	it	it	PRON
cord-301856-71syce4n	126	30	has	have	AUX
cord-301856-71syce4n	126	31	been	be	AUX
cord-301856-71syce4n	126	32	proposed	propose	VERB
cord-301856-71syce4n	126	33	that	that	SCONJ
cord-301856-71syce4n	126	34	these	these	DET
cord-301856-71syce4n	126	35	populations	population	NOUN
cord-301856-71syce4n	126	36	were	be	AUX
cord-301856-71syce4n	126	37	probably	probably	ADV
cord-301856-71syce4n	126	38	selected	select	VERB
cord-301856-71syce4n	126	39	through	through	ADP
cord-301856-71syce4n	126	40	genetic	genetic	ADJ
cord-301856-71syce4n	126	41	control	control	NOUN
cord-301856-71syce4n	126	42	of	of	ADP
cord-301856-71syce4n	126	43	survival	survival	NOUN
cord-301856-71syce4n	126	44	to	to	ADP
cord-301856-71syce4n	126	45	the	the	DET
cord-301856-71syce4n	126	46	epidemics	epidemic	NOUN
cord-301856-71syce4n	127	1	[	[	X
cord-301856-71syce4n	127	2	45	45	NUM
cord-301856-71syce4n	127	3	]	]	PUNCT
cord-301856-71syce4n	127	4	(	(	PUNCT
cord-301856-71syce4n	127	5	box	box	NOUN
cord-301856-71syce4n	127	6	3	3	NUM
cord-301856-71syce4n	127	7	)	)	PUNCT
cord-301856-71syce4n	127	8	.	.	PUNCT
cord-301856-71syce4n	128	1	africans	african	NOUN
cord-301856-71syce4n	128	2	and	and	CCONJ
cord-301856-71syce4n	128	3	americans	americans	PROPN
cord-301856-71syce4n	128	4	with	with	ADP
cord-301856-71syce4n	128	5	an	an	DET
cord-301856-71syce4n	128	6	african	african	ADJ
cord-301856-71syce4n	128	7	ancestry	ancestry	NOUN
cord-301856-71syce4n	128	8	present	present	VERB
cord-301856-71syce4n	128	9	a	a	DET
cord-301856-71syce4n	128	10	much	much	ADV
cord-301856-71syce4n	128	11	higher	high	ADJ
cord-301856-71syce4n	128	12	number	number	NOUN
cord-301856-71syce4n	128	13	of	of	ADP
cord-301856-71syce4n	128	14	genetic	genetic	ADJ
cord-301856-71syce4n	128	15	variants	variant	NOUN
cord-301856-71syce4n	128	16	related	relate	VERB
cord-301856-71syce4n	128	17	to	to	ADP
cord-301856-71syce4n	128	18	robust	robust	ADJ
cord-301856-71syce4n	128	19	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	128	20	reactions	reaction	NOUN
cord-301856-71syce4n	128	21	,	,	PUNCT
cord-301856-71syce4n	128	22	increased	increase	VERB
cord-301856-71syce4n	128	23	cytokine	cytokine	NOUN
cord-301856-71syce4n	128	24	secretion	secretion	NOUN
cord-301856-71syce4n	128	25	,	,	PUNCT
cord-301856-71syce4n	128	26	and	and	CCONJ
cord-301856-71syce4n	128	27	bactericidal	bactericidal	ADJ
cord-301856-71syce4n	128	28	activities	activity	NOUN
cord-301856-71syce4n	128	29	compared	compare	VERB
cord-301856-71syce4n	128	30	with	with	ADP
cord-301856-71syce4n	128	31	the	the	DET
cord-301856-71syce4n	128	32	other	other	ADJ
cord-301856-71syce4n	128	33	populations	population	NOUN
cord-301856-71syce4n	128	34	[	[	X
cord-301856-71syce4n	128	35	32	32	NUM
cord-301856-71syce4n	128	36	]	]	PUNCT
cord-301856-71syce4n	128	37	,	,	PUNCT
cord-301856-71syce4n	128	38	including	include	VERB
cord-301856-71syce4n	128	39	more	more	ADJ
cord-301856-71syce4n	128	40	than	than	ADP
cord-301856-71syce4n	128	41	250	250	NUM
cord-301856-71syce4n	128	42	genes	gene	NOUN
cord-301856-71syce4n	128	43	with	with	ADP
cord-301856-71syce4n	128	44	traces	trace	NOUN
cord-301856-71syce4n	128	45	of	of	ADP
cord-301856-71syce4n	128	46	recent	recent	ADJ
cord-301856-71syce4n	128	47	selection	selection	NOUN
cord-301856-71syce4n	128	48	,	,	PUNCT
cord-301856-71syce4n	128	49	such	such	ADJ
cord-301856-71syce4n	128	50	as	as	ADP
cord-301856-71syce4n	128	51	il1a	il1a	NOUN
cord-301856-71syce4n	128	52	and	and	CCONJ
cord-301856-71syce4n	128	53	il1b	il1b	VERB
cord-301856-71syce4n	128	54	gene	gene	NOUN
cord-301856-71syce4n	128	55	variants	variant	NOUN
cord-301856-71syce4n	128	56	[	[	X
cord-301856-71syce4n	128	57	46	46	NUM
cord-301856-71syce4n	128	58	]	]	PUNCT
cord-301856-71syce4n	128	59	.	.	PUNCT
cord-301856-71syce4n	129	1	the	the	DET
cord-301856-71syce4n	129	2	degree	degree	NOUN
cord-301856-71syce4n	129	3	of	of	ADP
cord-301856-71syce4n	129	4	african	african	ADJ
cord-301856-71syce4n	129	5	ancestry	ancestry	NOUN
cord-301856-71syce4n	129	6	,	,	PUNCT
cord-301856-71syce4n	129	7	analyzed	analyze	VERB
cord-301856-71syce4n	129	8	by	by	ADP
cord-301856-71syce4n	129	9	fine	fine	ADJ
cord-301856-71syce4n	129	10	-	-	PUNCT
cord-301856-71syce4n	129	11	mapping	mapping	NOUN
cord-301856-71syce4n	129	12	analysis	analysis	NOUN
cord-301856-71syce4n	129	13	refined	refine	VERB
cord-301856-71syce4n	129	14	to	to	ADP
cord-301856-71syce4n	129	15	the	the	DET
cord-301856-71syce4n	129	16	duffy	duffy	ADJ
cord-301856-71syce4n	129	17	-	-	PUNCT
cord-301856-71syce4n	129	18	null	null	PROPN
cord-301856-71syce4n	129	19	allele	allele	PROPN
cord-301856-71syce4n	129	20	of	of	ADP
cord-301856-71syce4n	129	21	rs2814778	rs2814778	PROPN
cord-301856-71syce4n	129	22	,	,	PUNCT
cord-301856-71syce4n	129	23	was	be	AUX
cord-301856-71syce4n	129	24	correlated	correlate	VERB
cord-301856-71syce4n	129	25	with	with	ADP
cord-301856-71syce4n	129	26	an	an	DET
cord-301856-71syce4n	129	27	increased	increase	VERB
cord-301856-71syce4n	129	28	amount	amount	NOUN
cord-301856-71syce4n	129	29	of	of	ADP
cord-301856-71syce4n	129	30	the	the	DET
cord-301856-71syce4n	129	31	proinflammatory	proinflammatory	ADJ
cord-301856-71syce4n	129	32	chemokines	chemokine	NOUN
cord-301856-71syce4n	129	33	ccl2	ccl2	PROPN
cord-301856-71syce4n	129	34	and	and	CCONJ
cord-301856-71syce4n	129	35	ccl11	ccl11	NOUN
cord-301856-71syce4n	129	36	in	in	ADP
cord-301856-71syce4n	129	37	plasma	plasma	NOUN
cord-301856-71syce4n	129	38	relative	relative	ADJ
cord-301856-71syce4n	129	39	to	to	ADP
cord-301856-71syce4n	129	40	controls	control	NOUN
cord-301856-71syce4n	129	41	[	[	SYM
cord-301856-71syce4n	129	42	12	12	NUM
cord-301856-71syce4n	129	43	]	]	PUNCT
cord-301856-71syce4n	129	44	.	.	PUNCT
cord-301856-71syce4n	130	1	a	a	DET
cord-301856-71syce4n	130	2	study	study	NOUN
cord-301856-71syce4n	130	3	involving	involve	VERB
cord-301856-71syce4n	130	4	12	12	NUM
cord-301856-71syce4n	130	5	000	000	NUM
cord-301856-71syce4n	130	6	african	african	ADJ
cord-301856-71syce4n	130	7	american	american	PROPN
cord-301856-71syce4n	130	8	and	and	CCONJ
cord-301856-71syce4n	130	9	hispanic	hispanic	PROPN
cord-301856-71syce4n	130	10	american	american	ADJ
cord-301856-71syce4n	130	11	women	woman	NOUN
cord-301856-71syce4n	130	12	found	find	VERB
cord-301856-71syce4n	130	13	that	that	SCONJ
cord-301856-71syce4n	130	14	the	the	DET
cord-301856-71syce4n	130	15	higher	high	ADJ
cord-301856-71syce4n	130	16	values	value	NOUN
cord-301856-71syce4n	130	17	of	of	ADP
cord-301856-71syce4n	130	18	c	c	X
cord-301856-71syce4n	130	19	-	-	PUNCT
cord-301856-71syce4n	130	20	reactive	reactive	ADJ
cord-301856-71syce4n	130	21	protein	protein	NOUN
cord-301856-71syce4n	130	22	(	(	PUNCT
cord-301856-71syce4n	130	23	crp	crp	PROPN
cord-301856-71syce4n	130	24	)	)	PUNCT
cord-301856-71syce4n	130	25	in	in	ADP
cord-301856-71syce4n	130	26	blood	blood	NOUN
cord-301856-71syce4n	130	27	found	find	VERB
cord-301856-71syce4n	130	28	in	in	ADP
cord-301856-71syce4n	130	29	these	these	DET
cord-301856-71syce4n	130	30	populations	population	NOUN
cord-301856-71syce4n	130	31	compared	compare	VERB
cord-301856-71syce4n	130	32	with	with	ADP
cord-301856-71syce4n	130	33	european	european	PROPN
cord-301856-71syce4n	130	34	americans	americans	PROPN
cord-301856-71syce4n	130	35	were	be	AUX
cord-301856-71syce4n	130	36	related	relate	VERB
cord-301856-71syce4n	130	37	to	to	ADP
cord-301856-71syce4n	130	38	a	a	DET
cord-301856-71syce4n	130	39	crp	crp	NOUN
cord-301856-71syce4n	130	40	-	-	PUNCT
cord-301856-71syce4n	130	41	associated	associate	VERB
cord-301856-71syce4n	130	42	variant	variant	NOUN
cord-301856-71syce4n	130	43	of	of	ADP
cord-301856-71syce4n	130	44	triggering	trigger	VERB
cord-301856-71syce4n	130	45	receptors	receptor	NOUN
cord-301856-71syce4n	130	46	expressed	express	VERB
cord-301856-71syce4n	130	47	by	by	ADP
cord-301856-71syce4n	130	48	myeloid	myeloid	PROPN
cord-301856-71syce4n	130	49	cells	cell	NOUN
cord-301856-71syce4n	130	50	2	2	NUM
cord-301856-71syce4n	130	51	(	(	PUNCT
cord-301856-71syce4n	130	52	trem2	trem2	NOUN
cord-301856-71syce4n	130	53	)	)	PUNCT
cord-301856-71syce4n	131	1	[	[	X
cord-301856-71syce4n	131	2	47	47	NUM
cord-301856-71syce4n	131	3	]	]	PUNCT
cord-301856-71syce4n	131	4	.	.	PUNCT
cord-301856-71syce4n	132	1	moreover	moreover	ADV
cord-301856-71syce4n	132	2	,	,	PUNCT
cord-301856-71syce4n	132	3	comparison	comparison	NOUN
cord-301856-71syce4n	132	4	of	of	ADP
cord-301856-71syce4n	132	5	health	health	NOUN
cord-301856-71syce4n	132	6	record	record	NOUN
cord-301856-71syce4n	132	7	data	datum	NOUN
cord-301856-71syce4n	132	8	from	from	ADP
cord-301856-71syce4n	132	9	individuals	individual	NOUN
cord-301856-71syce4n	132	10	with	with	ADP
cord-301856-71syce4n	132	11	connective	connective	ADJ
cord-301856-71syce4n	132	12	tissue	tissue	NOUN
cord-301856-71syce4n	132	13	diseases	disease	NOUN
cord-301856-71syce4n	132	14	,	,	PUNCT
cord-301856-71syce4n	132	15	including	include	VERB
cord-301856-71syce4n	132	16	rheumatoid	rheumatoid	NOUN
cord-301856-71syce4n	132	17	arthritis	arthritis	NOUN
cord-301856-71syce4n	132	18	and	and	CCONJ
cord-301856-71syce4n	132	19	systemic	systemic	ADJ
cord-301856-71syce4n	132	20	lupus	lupus	NOUN
cord-301856-71syce4n	132	21	erythematosus	erythematosus	NOUN
cord-301856-71syce4n	132	22	(	(	PUNCT
cord-301856-71syce4n	132	23	sle	sle	PROPN
cord-301856-71syce4n	132	24	)	)	PUNCT
cord-301856-71syce4n	132	25	,	,	PUNCT
cord-301856-71syce4n	132	26	as	as	ADV
cord-301856-71syce4n	132	27	well	well	ADV
cord-301856-71syce4n	132	28	as	as	ADP
cord-301856-71syce4n	132	29	atherosclerotic	atherosclerotic	ADJ
cord-301856-71syce4n	132	30	cardiovascular	cardiovascular	ADJ
cord-301856-71syce4n	132	31	disease	disease	NOUN
cord-301856-71syce4n	132	32	from	from	ADP
cord-301856-71syce4n	132	33	almost	almost	ADV
cord-301856-71syce4n	132	34	300	300	NUM
cord-301856-71syce4n	132	35	000	000	NUM
cord-301856-71syce4n	132	36	african	african	ADJ
cord-301856-71syce4n	132	37	american	american	PROPN
cord-301856-71syce4n	132	38	and	and	CCONJ
cord-301856-71syce4n	132	39	european	european	PROPN
cord-301856-71syce4n	132	40	american	american	ADJ
cord-301856-71syce4n	132	41	adults	adult	NOUN
cord-301856-71syce4n	132	42	was	be	AUX
cord-301856-71syce4n	132	43	conducted	conduct	VERB
cord-301856-71syce4n	132	44	;	;	PUNCT
cord-301856-71syce4n	132	45	the	the	DET
cord-301856-71syce4n	132	46	study	study	NOUN
cord-301856-71syce4n	132	47	reported	report	VERB
cord-301856-71syce4n	132	48	for	for	ADP
cord-301856-71syce4n	132	49	the	the	DET
cord-301856-71syce4n	132	50	latter	latter	ADJ
cord-301856-71syce4n	132	51	,	,	PUNCT
cord-301856-71syce4n	132	52	a	a	DET
cord-301856-71syce4n	132	53	prevalence	prevalence	NOUN
cord-301856-71syce4n	132	54	of	of	ADP
cord-301856-71syce4n	132	55	atherosclerotic	atherosclerotic	ADJ
cord-301856-71syce4n	132	56	cardiovascular	cardiovascular	ADJ
cord-301856-71syce4n	132	57	disease	disease	NOUN
cord-301856-71syce4n	132	58	in	in	ADP
cord-301856-71syce4n	132	59	29.7	29.7	NUM
cord-301856-71syce4n	132	60	%	%	NOUN
cord-301856-71syce4n	132	61	african	african	ADJ
cord-301856-71syce4n	132	62	americans	americans	PROPN
cord-301856-71syce4n	132	63	(	(	PUNCT
cord-301856-71syce4n	132	64	particularly	particularly	ADV
cord-301856-71syce4n	132	65	high	high	ADJ
cord-301856-71syce4n	132	66	in	in	ADP
cord-301856-71syce4n	132	67	young	young	ADJ
cord-301856-71syce4n	132	68	individuals	individual	NOUN
cord-301856-71syce4n	132	69	)	)	PUNCT
cord-301856-71syce4n	132	70	,	,	PUNCT
cord-301856-71syce4n	132	71	relative	relative	ADJ
cord-301856-71syce4n	132	72	to	to	ADP
cord-301856-71syce4n	132	73	14.7	14.7	NUM
cord-301856-71syce4n	132	74	%	%	NOUN
cord-301856-71syce4n	132	75	in	in	ADP
cord-301856-71syce4n	132	76	european	european	PROPN
cord-301856-71syce4n	132	77	americans	americans	PROPN
cord-301856-71syce4n	132	78	[	[	PUNCT
cord-301856-71syce4n	132	79	48	48	NUM
cord-301856-71syce4n	132	80	]	]	PUNCT
cord-301856-71syce4n	132	81	.	.	PUNCT
cord-301856-71syce4n	133	1	these	these	DET
cord-301856-71syce4n	133	2	studies	study	NOUN
cord-301856-71syce4n	133	3	highlight	highlight	VERB
cord-301856-71syce4n	133	4	certain	certain	ADJ
cord-301856-71syce4n	133	5	genetic	genetic	ADJ
cord-301856-71syce4n	133	6	links	link	NOUN
cord-301856-71syce4n	133	7	to	to	ADP
cord-301856-71syce4n	133	8	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	133	9	predisposition	predisposition	NOUN
cord-301856-71syce4n	133	10	/	/	SYM
cord-301856-71syce4n	133	11	manifestation	manifestation	NOUN
cord-301856-71syce4n	133	12	.	.	PUNCT
cord-301856-71syce4n	134	1	however	however	ADV
cord-301856-71syce4n	134	2	,	,	PUNCT
cord-301856-71syce4n	134	3	increased	increase	VERB
cord-301856-71syce4n	134	4	proinflammatory	proinflammatory	ADJ
cord-301856-71syce4n	134	5	activity	activity	NOUN
cord-301856-71syce4n	134	6	is	be	AUX
cord-301856-71syce4n	134	7	a	a	DET
cord-301856-71syce4n	134	8	double	double	ADJ
cord-301856-71syce4n	134	9	-	-	PUNCT
cord-301856-71syce4n	134	10	edged	edge	VERB
cord-301856-71syce4n	134	11	sword	sword	NOUN
cord-301856-71syce4n	134	12	.	.	PUNCT
cord-301856-71syce4n	135	1	in	in	ADP
cord-301856-71syce4n	135	2	the	the	DET
cord-301856-71syce4n	135	3	absence	absence	NOUN
cord-301856-71syce4n	135	4	of	of	ADP
cord-301856-71syce4n	135	5	regular	regular	ADJ
cord-301856-71syce4n	135	6	pathogen	pathogen	PROPN
cord-301856-71syce4n	135	7	challenges	challenge	NOUN
cord-301856-71syce4n	135	8	that	that	PRON
cord-301856-71syce4n	135	9	require	require	VERB
cord-301856-71syce4n	135	10	maintained	maintain	VERB
cord-301856-71syce4n	135	11	modulation	modulation	NOUN
cord-301856-71syce4n	135	12	of	of	ADP
cord-301856-71syce4n	135	13	the	the	DET
cord-301856-71syce4n	135	14	balance	balance	NOUN
cord-301856-71syce4n	135	15	between	between	ADP
cord-301856-71syce4n	135	16	inflammation	inflammation	NOUN
cord-301856-71syce4n	135	17	and	and	CCONJ
cord-301856-71syce4n	135	18	suppression	suppression	NOUN
cord-301856-71syce4n	135	19	of	of	ADP
cord-301856-71syce4n	135	20	the	the	DET
cord-301856-71syce4n	135	21	immune	immune	ADJ
cord-301856-71syce4n	135	22	response	response	NOUN
cord-301856-71syce4n	135	23	,	,	PUNCT
cord-301856-71syce4n	135	24	the	the	DET
cord-301856-71syce4n	135	25	organism	organism	NOUN
cord-301856-71syce4n	135	26	can	can	AUX
cord-301856-71syce4n	135	27	overreact	overreact	VERB
cord-301856-71syce4n	135	28	to	to	ADP
cord-301856-71syce4n	135	29	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	135	30	stimuli	stimulus	NOUN
cord-301856-71syce4n	135	31	and	and	CCONJ
cord-301856-71syce4n	135	32	trigger	trigger	VERB
cord-301856-71syce4n	135	33	exacerbated	exacerbate	VERB
cord-301856-71syce4n	135	34	responses	response	NOUN
cord-301856-71syce4n	135	35	.	.	PUNCT
cord-301856-71syce4n	136	1	for	for	ADP
cord-301856-71syce4n	136	2	instance	instance	NOUN
cord-301856-71syce4n	136	3	,	,	PUNCT
cord-301856-71syce4n	136	4	descendants	descendant	NOUN
cord-301856-71syce4n	136	5	of	of	ADP
cord-301856-71syce4n	136	6	african	african	ADJ
cord-301856-71syce4n	136	7	populations	population	NOUN
cord-301856-71syce4n	136	8	generally	generally	ADV
cord-301856-71syce4n	136	9	present	present	VERB
cord-301856-71syce4n	136	10	higher	high	ADJ
cord-301856-71syce4n	136	11	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	136	12	to	to	ADP
cord-301856-71syce4n	136	13	a	a	DET
cord-301856-71syce4n	136	14	variety	variety	NOUN
cord-301856-71syce4n	136	15	of	of	ADP
cord-301856-71syce4n	136	16	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	136	17	syndromes	syndrome	NOUN
cord-301856-71syce4n	136	18	such	such	ADJ
cord-301856-71syce4n	136	19	as	as	ADP
cord-301856-71syce4n	136	20	inflammation	inflammation	NOUN
cord-301856-71syce4n	136	21	-	-	PUNCT
cord-301856-71syce4n	136	22	associated	associate	VERB
cord-301856-71syce4n	136	23	carcinomas	carcinoma	NOUN
cord-301856-71syce4n	136	24	,	,	PUNCT
cord-301856-71syce4n	136	25	lupus	lupus	NOUN
cord-301856-71syce4n	136	26	,	,	PUNCT
cord-301856-71syce4n	136	27	asthma	asthma	NOUN
cord-301856-71syce4n	136	28	,	,	PUNCT
cord-301856-71syce4n	136	29	and	and	CCONJ
cord-301856-71syce4n	136	30	multiple	multiple	ADJ
cord-301856-71syce4n	136	31	sclerosis	sclerosis	NOUN
cord-301856-71syce4n	136	32	(	(	PUNCT
cord-301856-71syce4n	136	33	ms	ms	PROPN
cord-301856-71syce4n	136	34	)	)	PUNCT
cord-301856-71syce4n	136	35	,	,	PUNCT
cord-301856-71syce4n	136	36	the	the	DET
cord-301856-71syce4n	136	37	overall	overall	ADJ
cord-301856-71syce4n	136	38	prevalence	prevalence	NOUN
cord-301856-71syce4n	136	39	of	of	ADP
cord-301856-71syce4n	136	40	which	which	PRON
cord-301856-71syce4n	136	41	is	be	AUX
cord-301856-71syce4n	136	42	up	up	ADP
cord-301856-71syce4n	136	43	to	to	PART
cord-301856-71syce4n	136	44	three	three	NUM
cord-301856-71syce4n	136	45	times	time	NOUN
cord-301856-71syce4n	136	46	higher	high	ADJ
cord-301856-71syce4n	136	47	in	in	ADP
cord-301856-71syce4n	136	48	individuals	individual	NOUN
cord-301856-71syce4n	136	49	with	with	ADP
cord-301856-71syce4n	136	50	african	african	ADJ
cord-301856-71syce4n	136	51	ancestry	ancestry	PROPN
cord-301856-71syce4n	136	52	relative	relative	ADJ
cord-301856-71syce4n	136	53	to	to	ADP
cord-301856-71syce4n	136	54	individuals	individual	NOUN
cord-301856-71syce4n	136	55	with	with	ADP
cord-301856-71syce4n	136	56	european	european	PROPN
cord-301856-71syce4n	136	57	ancestry	ancestry	PROPN
cord-301856-71syce4n	136	58	[	[	PUNCT
cord-301856-71syce4n	136	59	31	31	NUM
cord-301856-71syce4n	136	60	,	,	PUNCT
cord-301856-71syce4n	136	61	49	49	NUM
cord-301856-71syce4n	136	62	,	,	PUNCT
cord-301856-71syce4n	136	63	50	50	NUM
cord-301856-71syce4n	136	64	]	]	PUNCT
cord-301856-71syce4n	136	65	.	.	PUNCT
cord-301856-71syce4n	137	1	there	there	PRON
cord-301856-71syce4n	137	2	are	be	VERB
cord-301856-71syce4n	137	3	extensive	extensive	ADJ
cord-301856-71syce4n	137	4	differences	difference	NOUN
cord-301856-71syce4n	137	5	in	in	ADP
cord-301856-71syce4n	137	6	immune	immune	ADJ
cord-301856-71syce4n	137	7	cell	cell	NOUN
cord-301856-71syce4n	137	8	gene	gene	NOUN
cord-301856-71syce4n	137	9	expression	expression	NOUN
cord-301856-71syce4n	137	10	between	between	ADP
cord-301856-71syce4n	137	11	americans	americans	PROPN
cord-301856-71syce4n	137	12	with	with	ADP
cord-301856-71syce4n	137	13	african	african	ADJ
cord-301856-71syce4n	137	14	and	and	CCONJ
cord-301856-71syce4n	137	15	european	european	PROPN
cord-301856-71syce4n	137	16	ancestry	ancestry	PROPN
cord-301856-71syce4n	137	17	.	.	PUNCT
cord-301856-71syce4n	138	1	the	the	DET
cord-301856-71syce4n	138	2	increased	increase	VERB
cord-301856-71syce4n	138	3	proinflammatory	proinflammatory	ADJ
cord-301856-71syce4n	138	4	responses	response	NOUN
cord-301856-71syce4n	138	5	observed	observe	VERB
cord-301856-71syce4n	138	6	in	in	ADP
cord-301856-71syce4n	138	7	american	american	ADJ
cord-301856-71syce4n	138	8	individuals	individual	NOUN
cord-301856-71syce4n	138	9	relative	relative	ADJ
cord-301856-71syce4n	138	10	to	to	ADP
cord-301856-71syce4n	138	11	other	other	ADJ
cord-301856-71syce4n	138	12	populations	population	NOUN
cord-301856-71syce4n	138	13	might	might	AUX
cord-301856-71syce4n	138	14	be	be	AUX
cord-301856-71syce4n	138	15	beneficial	beneficial	ADJ
cord-301856-71syce4n	138	16	to	to	ADP
cord-301856-71syce4n	138	17	combatting	combat	VERB
cord-301856-71syce4n	138	18	infections	infection	NOUN
cord-301856-71syce4n	138	19	,	,	PUNCT
cord-301856-71syce4n	138	20	but	but	CCONJ
cord-301856-71syce4n	138	21	might	might	AUX
cord-301856-71syce4n	138	22	also	also	ADV
cord-301856-71syce4n	138	23	increase	increase	VERB
cord-301856-71syce4n	138	24	the	the	DET
cord-301856-71syce4n	138	25	chances	chance	NOUN
cord-301856-71syce4n	138	26	of	of	ADP
cord-301856-71syce4n	138	27	developing	develop	VERB
cord-301856-71syce4n	138	28	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	138	29	and	and	CCONJ
cord-301856-71syce4n	138	30	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	138	31	disorders	disorder	NOUN
cord-301856-71syce4n	138	32	,	,	PUNCT
cord-301856-71syce4n	138	33	which	which	PRON
cord-301856-71syce4n	138	34	warrants	warrant	VERB
cord-301856-71syce4n	138	35	further	further	ADJ
cord-301856-71syce4n	138	36	investigation	investigation	NOUN
cord-301856-71syce4n	138	37	.	.	PUNCT
cord-301856-71syce4n	139	1	our	our	PRON
cord-301856-71syce4n	139	2	gastrointestinal	gastrointestinal	ADJ
cord-301856-71syce4n	139	3	tract	tract	NOUN
cord-301856-71syce4n	139	4	provides	provide	VERB
cord-301856-71syce4n	139	5	residence	residence	NOUN
cord-301856-71syce4n	139	6	to	to	ADP
cord-301856-71syce4n	139	7	both	both	CCONJ
cord-301856-71syce4n	139	8	beneficial	beneficial	ADJ
cord-301856-71syce4n	139	9	and	and	CCONJ
cord-301856-71syce4n	139	10	potentially	potentially	ADV
cord-301856-71syce4n	139	11	pathogenic	pathogenic	ADJ
cord-301856-71syce4n	139	12	microorganisms	microorganism	NOUN
cord-301856-71syce4n	139	13	,	,	PUNCT
cord-301856-71syce4n	139	14	harboring	harbor	VERB
cord-301856-71syce4n	139	15	ten	ten	NUM
cord-301856-71syce4n	139	16	million	million	NUM
cord-301856-71syce4n	139	17	different	different	ADJ
cord-301856-71syce4n	139	18	microbial	microbial	ADJ
cord-301856-71syce4n	139	19	genes	gene	NOUN
cord-301856-71syce4n	139	20	in	in	ADP
cord-301856-71syce4n	139	21	the	the	DET
cord-301856-71syce4n	139	22	human	human	ADJ
cord-301856-71syce4n	139	23	fecal	fecal	ADJ
cord-301856-71syce4n	139	24	microbiome	microbiome	NOUN
cord-301856-71syce4n	139	25	[	[	X
cord-301856-71syce4n	139	26	51	51	NUM
cord-301856-71syce4n	139	27	]	]	PUNCT
cord-301856-71syce4n	139	28	.	.	PUNCT
cord-301856-71syce4n	140	1	the	the	DET
cord-301856-71syce4n	140	2	microbiome	microbiome	NOUN
cord-301856-71syce4n	140	3	has	have	VERB
cord-301856-71syce4n	140	4	its	its	PRON
cord-301856-71syce4n	140	5	own	own	ADJ
cord-301856-71syce4n	140	6	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	140	7	scenario	scenario	NOUN
cord-301856-71syce4n	140	8	across	across	ADP
cord-301856-71syce4n	140	9	different	different	ADJ
cord-301856-71syce4n	140	10	populations	population	NOUN
cord-301856-71syce4n	140	11	with	with	ADP
cord-301856-71syce4n	140	12	divergent	divergent	ADJ
cord-301856-71syce4n	140	13	lifestyles	lifestyle	NOUN
cord-301856-71syce4n	140	14	,	,	PUNCT
cord-301856-71syce4n	140	15	nutrition	nutrition	NOUN
cord-301856-71syce4n	140	16	,	,	PUNCT
cord-301856-71syce4n	140	17	and	and	CCONJ
cord-301856-71syce4n	140	18	exposure	exposure	NOUN
cord-301856-71syce4n	140	19	to	to	ADP
cord-301856-71syce4n	140	20	environmental	environmental	ADJ
cord-301856-71syce4n	140	21	agents	agent	NOUN
cord-301856-71syce4n	140	22	,	,	PUNCT
cord-301856-71syce4n	140	23	generating	generate	VERB
cord-301856-71syce4n	140	24	extraordinary	extraordinary	ADJ
cord-301856-71syce4n	140	25	heterogeneity	heterogeneity	NOUN
cord-301856-71syce4n	140	26	.	.	PUNCT
cord-301856-71syce4n	141	1	the	the	DET
cord-301856-71syce4n	141	2	ongoing	ongoing	ADJ
cord-301856-71syce4n	141	3	process	process	NOUN
cord-301856-71syce4n	141	4	of	of	ADP
cord-301856-71syce4n	141	5	'	'	PUNCT
cord-301856-71syce4n	141	6	lifestyle	lifestyle	NOUN
cord-301856-71syce4n	141	7	westernization	westernization	NOUN
cord-301856-71syce4n	141	8	'	'	PUNCT
cord-301856-71syce4n	141	9	of	of	ADP
cord-301856-71syce4n	141	10	different	different	ADJ
cord-301856-71syce4n	141	11	societies	society	NOUN
cord-301856-71syce4n	141	12	has	have	VERB
cord-301856-71syce4n	141	13	an	an	DET
cord-301856-71syce4n	141	14	important	important	ADJ
cord-301856-71syce4n	141	15	impact	impact	NOUN
cord-301856-71syce4n	141	16	on	on	ADP
cord-301856-71syce4n	141	17	the	the	DET
cord-301856-71syce4n	141	18	mutualistic	mutualistic	ADJ
cord-301856-71syce4n	141	19	relationships	relationship	NOUN
cord-301856-71syce4n	141	20	between	between	ADP
cord-301856-71syce4n	141	21	humans	human	NOUN
cord-301856-71syce4n	141	22	and	and	CCONJ
cord-301856-71syce4n	141	23	commensal	commensal	ADJ
cord-301856-71syce4n	141	24	organisms	organism	NOUN
cord-301856-71syce4n	141	25	worldwide	worldwide	ADV
cord-301856-71syce4n	141	26	.	.	PUNCT
cord-301856-71syce4n	142	1	african	african	ADJ
cord-301856-71syce4n	142	2	tribes	tribe	NOUN
cord-301856-71syce4n	142	3	are	be	AUX
cord-301856-71syce4n	142	4	adopting	adopt	VERB
cord-301856-71syce4n	142	5	western	western	ADJ
cord-301856-71syce4n	142	6	subsistence	subsistence	NOUN
cord-301856-71syce4n	142	7	patterns	pattern	NOUN
cord-301856-71syce4n	142	8	,	,	PUNCT
cord-301856-71syce4n	142	9	leading	lead	VERB
cord-301856-71syce4n	142	10	to	to	ADP
cord-301856-71syce4n	142	11	remarkable	remarkable	ADJ
cord-301856-71syce4n	142	12	changes	change	NOUN
cord-301856-71syce4n	142	13	in	in	ADP
cord-301856-71syce4n	142	14	the	the	DET
cord-301856-71syce4n	142	15	composition	composition	NOUN
cord-301856-71syce4n	142	16	of	of	ADP
cord-301856-71syce4n	142	17	their	their	PRON
cord-301856-71syce4n	142	18	microbiota	microbiota	NOUN
cord-301856-71syce4n	142	19	[	[	X
cord-301856-71syce4n	142	20	52	52	NUM
cord-301856-71syce4n	142	21	]	]	PUNCT
cord-301856-71syce4n	142	22	.	.	PUNCT
cord-301856-71syce4n	143	1	the	the	DET
cord-301856-71syce4n	143	2	comparison	comparison	NOUN
cord-301856-71syce4n	143	3	of	of	ADP
cord-301856-71syce4n	143	4	the	the	DET
cord-301856-71syce4n	143	5	intestinal	intestinal	ADJ
cord-301856-71syce4n	143	6	flora	flora	NOUN
cord-301856-71syce4n	143	7	of	of	ADP
cord-301856-71syce4n	143	8	the	the	DET
cord-301856-71syce4n	143	9	baaka	baaka	ADJ
cord-301856-71syce4n	143	10	hunter	hunter	NOUN
cord-301856-71syce4n	143	11	-	-	PUNCT
cord-301856-71syce4n	143	12	gatherers	gatherer	NOUN
cord-301856-71syce4n	143	13	and	and	CCONJ
cord-301856-71syce4n	143	14	the	the	DET
cord-301856-71syce4n	143	15	bantu	bantu	NOUN
cord-301856-71syce4n	143	16	agriculturalists	agriculturalist	NOUN
cord-301856-71syce4n	143	17	(	(	PUNCT
cord-301856-71syce4n	143	18	both	both	PRON
cord-301856-71syce4n	143	19	from	from	ADP
cord-301856-71syce4n	143	20	the	the	DET
cord-301856-71syce4n	143	21	central	central	PROPN
cord-301856-71syce4n	143	22	africa	africa	PROPN
cord-301856-71syce4n	143	23	republic	republic	PROPN
cord-301856-71syce4n	143	24	)	)	PUNCT
cord-301856-71syce4n	143	25	,	,	PUNCT
cord-301856-71syce4n	143	26	with	with	ADP
cord-301856-71syce4n	143	27	a	a	DET
cord-301856-71syce4n	143	28	group	group	NOUN
cord-301856-71syce4n	143	29	of	of	ADP
cord-301856-71syce4n	143	30	us	us	PROPN
cord-301856-71syce4n	143	31	-	-	PUNCT
cord-301856-71syce4n	143	32	born	bear	VERB
cord-301856-71syce4n	143	33	african	african	ADJ
cord-301856-71syce4n	143	34	americans	americans	PROPN
cord-301856-71syce4n	143	35	showed	show	VERB
cord-301856-71syce4n	143	36	a	a	DET
cord-301856-71syce4n	143	37	great	great	ADJ
cord-301856-71syce4n	143	38	example	example	NOUN
cord-301856-71syce4n	143	39	of	of	ADP
cord-301856-71syce4n	143	40	the	the	DET
cord-301856-71syce4n	143	41	evolution	evolution	NOUN
cord-301856-71syce4n	143	42	of	of	ADP
cord-301856-71syce4n	143	43	the	the	DET
cord-301856-71syce4n	143	44	human	human	ADJ
cord-301856-71syce4n	143	45	microbiome	microbiome	NOUN
cord-301856-71syce4n	143	46	[	[	X
cord-301856-71syce4n	143	47	52	52	NUM
cord-301856-71syce4n	143	48	]	]	PUNCT
cord-301856-71syce4n	143	49	.	.	PUNCT
cord-301856-71syce4n	144	1	specifically	specifically	ADV
cord-301856-71syce4n	144	2	,	,	PUNCT
cord-301856-71syce4n	144	3	the	the	DET
cord-301856-71syce4n	144	4	bantu	bantu	NOUN
cord-301856-71syce4n	144	5	,	,	PUNCT
cord-301856-71syce4n	144	6	still	still	ADV
cord-301856-71syce4n	144	7	engaged	engage	VERB
cord-301856-71syce4n	144	8	in	in	ADP
cord-301856-71syce4n	144	9	hunting	hunting	NOUN
cord-301856-71syce4n	144	10	,	,	PUNCT
cord-301856-71syce4n	144	11	have	have	VERB
cord-301856-71syce4n	144	12	a	a	DET
cord-301856-71syce4n	144	13	greater	great	ADJ
cord-301856-71syce4n	144	14	bacterial	bacterial	ADJ
cord-301856-71syce4n	144	15	gut	gut	NOUN
cord-301856-71syce4n	144	16	diversity	diversity	NOUN
cord-301856-71syce4n	144	17	than	than	ADP
cord-301856-71syce4n	144	18	their	their	PRON
cord-301856-71syce4n	144	19	baaka	baaka	ADJ
cord-301856-71syce4n	144	20	neighbors	neighbor	NOUN
cord-301856-71syce4n	144	21	,	,	PUNCT
cord-301856-71syce4n	144	22	who	who	PRON
cord-301856-71syce4n	144	23	left	leave	VERB
cord-301856-71syce4n	144	24	the	the	DET
cord-301856-71syce4n	144	25	jungle	jungle	NOUN
cord-301856-71syce4n	144	26	for	for	ADP
cord-301856-71syce4n	144	27	agriculture	agriculture	NOUN
cord-301856-71syce4n	144	28	,	,	PUNCT
cord-301856-71syce4n	144	29	and	and	CCONJ
cord-301856-71syce4n	144	30	even	even	ADV
cord-301856-71syce4n	144	31	more	more	ADJ
cord-301856-71syce4n	144	32	than	than	ADP
cord-301856-71syce4n	144	33	urbanized	urbanized	ADJ
cord-301856-71syce4n	144	34	westerners	westerner	NOUN
cord-301856-71syce4n	144	35	(	(	PUNCT
cord-301856-71syce4n	144	36	us	us	PROPN
cord-301856-71syce4n	144	37	african	african	PROPN
cord-301856-71syce4n	144	38	-	-	PUNCT
cord-301856-71syce4n	144	39	americans	americans	PROPN
cord-301856-71syce4n	144	40	)	)	PUNCT
cord-301856-71syce4n	145	1	[	[	X
cord-301856-71syce4n	145	2	52	52	NUM
cord-301856-71syce4n	145	3	]	]	PUNCT
cord-301856-71syce4n	145	4	.	.	PUNCT
cord-301856-71syce4n	146	1	this	this	DET
cord-301856-71syce4n	146	2	reduced	reduce	VERB
cord-301856-71syce4n	146	3	microbiota	microbiota	PROPN
cord-301856-71syce4n	146	4	diversity	diversity	NOUN
cord-301856-71syce4n	146	5	in	in	ADP
cord-301856-71syce4n	146	6	western	western	ADJ
cord-301856-71syce4n	146	7	societies	society	NOUN
cord-301856-71syce4n	146	8	has	have	AUX
cord-301856-71syce4n	146	9	been	be	AUX
cord-301856-71syce4n	146	10	associated	associate	VERB
cord-301856-71syce4n	146	11	with	with	ADP
cord-301856-71syce4n	146	12	a	a	DET
cord-301856-71syce4n	146	13	higher	high	ADJ
cord-301856-71syce4n	146	14	incidence	incidence	NOUN
cord-301856-71syce4n	146	15	of	of	ADP
cord-301856-71syce4n	146	16	the	the	DET
cord-301856-71syce4n	146	17	so	so	ADV
cord-301856-71syce4n	146	18	-	-	PUNCT
cord-301856-71syce4n	146	19	called	call	VERB
cord-301856-71syce4n	146	20	'	'	PUNCT
cord-301856-71syce4n	146	21	diseases	disease	NOUN
cord-301856-71syce4n	146	22	of	of	ADP
cord-301856-71syce4n	146	23	civilization	civilization	NOUN
cord-301856-71syce4n	146	24	'	'	PUNCT
cord-301856-71syce4n	146	25	such	such	ADJ
cord-301856-71syce4n	146	26	as	as	ADP
cord-301856-71syce4n	146	27	cardiovascular	cardiovascular	ADJ
cord-301856-71syce4n	146	28	diseases	disease	NOUN
cord-301856-71syce4n	146	29	,	,	PUNCT
cord-301856-71syce4n	146	30	diabetes	diabetes	NOUN
cord-301856-71syce4n	146	31	,	,	PUNCT
cord-301856-71syce4n	146	32	obesity	obesity	NOUN
cord-301856-71syce4n	146	33	,	,	PUNCT
cord-301856-71syce4n	146	34	and	and	CCONJ
cord-301856-71syce4n	146	35	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	146	36	disorders	disorder	NOUN
cord-301856-71syce4n	146	37	,	,	PUNCT
cord-301856-71syce4n	146	38	which	which	PRON
cord-301856-71syce4n	146	39	are	be	AUX
cord-301856-71syce4n	146	40	very	very	ADV
cord-301856-71syce4n	146	41	unusual	unusual	ADJ
cord-301856-71syce4n	146	42	in	in	ADP
cord-301856-71syce4n	146	43	hunter	hunter	NOUN
cord-301856-71syce4n	146	44	-	-	PUNCT
cord-301856-71syce4n	146	45	gatherer	gatherer	NOUN
cord-301856-71syce4n	146	46	societies	society	NOUN
cord-301856-71syce4n	146	47	compared	compare	VERB
cord-301856-71syce4n	146	48	with	with	ADP
cord-301856-71syce4n	146	49	communities	community	NOUN
cord-301856-71syce4n	146	50	living	live	VERB
cord-301856-71syce4n	146	51	a	a	DET
cord-301856-71syce4n	146	52	western	western	ADJ
cord-301856-71syce4n	146	53	-	-	PUNCT
cord-301856-71syce4n	146	54	type	type	NOUN
cord-301856-71syce4n	146	55	lifestyle	lifestyle	NOUN
cord-301856-71syce4n	146	56	[	[	PUNCT
cord-301856-71syce4n	146	57	52	52	NUM
cord-301856-71syce4n	146	58	,	,	PUNCT
cord-301856-71syce4n	146	59	53	53	NUM
cord-301856-71syce4n	146	60	]	]	PUNCT
cord-301856-71syce4n	146	61	.	.	PUNCT
cord-301856-71syce4n	147	1	although	although	SCONJ
cord-301856-71syce4n	147	2	viruses	virus	NOUN
cord-301856-71syce4n	147	3	are	be	AUX
cord-301856-71syce4n	147	4	mainly	mainly	ADV
cord-301856-71syce4n	147	5	seen	see	VERB
cord-301856-71syce4n	147	6	as	as	ADP
cord-301856-71syce4n	147	7	pathogenic	pathogenic	ADJ
cord-301856-71syce4n	147	8	agents	agent	NOUN
cord-301856-71syce4n	147	9	,	,	PUNCT
cord-301856-71syce4n	147	10	they	they	PRON
cord-301856-71syce4n	147	11	also	also	ADV
cord-301856-71syce4n	147	12	play	play	VERB
cord-301856-71syce4n	147	13	a	a	DET
cord-301856-71syce4n	147	14	fundamental	fundamental	ADJ
cord-301856-71syce4n	147	15	role	role	NOUN
cord-301856-71syce4n	147	16	in	in	ADP
cord-301856-71syce4n	147	17	the	the	DET
cord-301856-71syce4n	147	18	evolution	evolution	NOUN
cord-301856-71syce4n	147	19	and	and	CCONJ
cord-301856-71syce4n	147	20	maturation	maturation	NOUN
cord-301856-71syce4n	147	21	of	of	ADP
cord-301856-71syce4n	147	22	the	the	DET
cord-301856-71syce4n	147	23	human	human	ADJ
cord-301856-71syce4n	147	24	immune	immune	ADJ
cord-301856-71syce4n	147	25	system	system	NOUN
cord-301856-71syce4n	147	26	[	[	PUNCT
cord-301856-71syce4n	147	27	54	54	NUM
cord-301856-71syce4n	147	28	,	,	PUNCT
cord-301856-71syce4n	147	29	55	55	NUM
cord-301856-71syce4n	147	30	]	]	PUNCT
cord-301856-71syce4n	147	31	.	.	PUNCT
cord-301856-71syce4n	148	1	approximately	approximately	ADV
cord-301856-71syce4n	148	2	8	8	NUM
cord-301856-71syce4n	148	3	%	%	NOUN
cord-301856-71syce4n	148	4	of	of	ADP
cord-301856-71syce4n	148	5	the	the	DET
cord-301856-71syce4n	148	6	human	human	ADJ
cord-301856-71syce4n	148	7	genome	genome	NOUN
cord-301856-71syce4n	148	8	is	be	AUX
cord-301856-71syce4n	148	9	composed	compose	VERB
cord-301856-71syce4n	148	10	of	of	ADP
cord-301856-71syce4n	148	11	endogenous	endogenous	ADJ
cord-301856-71syce4n	148	12	retroviruses	retrovirus	NOUN
cord-301856-71syce4n	148	13	(	(	PUNCT
cord-301856-71syce4n	148	14	ervs	ervs	NOUN
cord-301856-71syce4n	148	15	)	)	PUNCT
cord-301856-71syce4n	148	16	,	,	PUNCT
cord-301856-71syce4n	148	17	sequences	sequence	NOUN
cord-301856-71syce4n	148	18	derived	derive	VERB
cord-301856-71syce4n	148	19	from	from	ADP
cord-301856-71syce4n	148	20	past	past	ADJ
cord-301856-71syce4n	148	21	retroviral	retroviral	ADJ
cord-301856-71syce4n	148	22	infections	infection	NOUN
cord-301856-71syce4n	148	23	and	and	CCONJ
cord-301856-71syce4n	148	24	permanently	permanently	ADV
cord-301856-71syce4n	148	25	inserted	insert	VERB
cord-301856-71syce4n	148	26	into	into	ADP
cord-301856-71syce4n	148	27	different	different	ADJ
cord-301856-71syce4n	148	28	regions	region	NOUN
cord-301856-71syce4n	148	29	of	of	ADP
cord-301856-71syce4n	148	30	the	the	DET
cord-301856-71syce4n	148	31	human	human	ADJ
cord-301856-71syce4n	148	32	genome	genome	NOUN
cord-301856-71syce4n	148	33	[	[	PUNCT
cord-301856-71syce4n	148	34	56	56	NUM
cord-301856-71syce4n	148	35	]	]	PUNCT
cord-301856-71syce4n	148	36	.	.	PUNCT
cord-301856-71syce4n	149	1	one	one	NUM
cord-301856-71syce4n	149	2	study	study	NOUN
cord-301856-71syce4n	149	3	showed	show	VERB
cord-301856-71syce4n	149	4	that	that	SCONJ
cord-301856-71syce4n	149	5	ervs	ervs	NOUN
cord-301856-71syce4n	149	6	played	play	VERB
cord-301856-71syce4n	149	7	a	a	DET
cord-301856-71syce4n	149	8	central	central	ADJ
cord-301856-71syce4n	149	9	role	role	NOUN
cord-301856-71syce4n	149	10	in	in	ADP
cord-301856-71syce4n	149	11	the	the	DET
cord-301856-71syce4n	149	12	induction	induction	NOUN
cord-301856-71syce4n	149	13	of	of	ADP
cord-301856-71syce4n	149	14	ifn	ifn	ADJ
cord-301856-71syce4n	149	15	-	-	PUNCT
cord-301856-71syce4n	149	16	dependent	dependent	ADJ
cord-301856-71syce4n	149	17	immune	immune	ADJ
cord-301856-71syce4n	149	18	responses	response	NOUN
cord-301856-71syce4n	149	19	and	and	CCONJ
cord-301856-71syce4n	149	20	that	that	SCONJ
cord-301856-71syce4n	149	21	the	the	DET
cord-301856-71syce4n	149	22	removal	removal	NOUN
cord-301856-71syce4n	149	23	of	of	ADP
cord-301856-71syce4n	149	24	one	one	NUM
cord-301856-71syce4n	149	25	or	or	CCONJ
cord-301856-71syce4n	149	26	more	more	ADJ
cord-301856-71syce4n	149	27	of	of	ADP
cord-301856-71syce4n	149	28	these	these	DET
cord-301856-71syce4n	149	29	viral	viral	ADJ
cord-301856-71syce4n	149	30	dna	dna	NOUN
cord-301856-71syce4n	149	31	elements	element	NOUN
cord-301856-71syce4n	149	32	in	in	ADP
cord-301856-71syce4n	149	33	the	the	DET
cord-301856-71syce4n	149	34	hela	hela	PROPN
cord-301856-71syce4n	149	35	human	human	PROPN
cord-301856-71syce4n	149	36	cell	cell	NOUN
cord-301856-71syce4n	149	37	line	line	NOUN
cord-301856-71syce4n	149	38	severely	severely	ADV
cord-301856-71syce4n	149	39	impaired	impair	VERB
cord-301856-71syce4n	149	40	the	the	DET
cord-301856-71syce4n	149	41	recruitment	recruitment	NOUN
cord-301856-71syce4n	149	42	of	of	ADP
cord-301856-71syce4n	149	43	transcription	transcription	NOUN
cord-301856-71syce4n	149	44	factors	factor	NOUN
cord-301856-71syce4n	149	45	necessary	necessary	ADJ
cord-301856-71syce4n	149	46	to	to	PART
cord-301856-71syce4n	149	47	trigger	trigger	VERB
cord-301856-71syce4n	149	48	the	the	DET
cord-301856-71syce4n	149	49	expression	expression	NOUN
cord-301856-71syce4n	149	50	of	of	ADP
cord-301856-71syce4n	149	51	ifng	ifng	PROPN
cord-301856-71syce4n	149	52	against	against	ADP
cord-301856-71syce4n	149	53	vaccinia	vaccinia	PROPN
cord-301856-71syce4n	149	54	virus	virus	PROPN
cord-301856-71syce4n	149	55	infection	infection	NOUN
cord-301856-71syce4n	149	56	relative	relative	ADJ
cord-301856-71syce4n	149	57	to	to	ADP
cord-301856-71syce4n	149	58	controls	control	NOUN
cord-301856-71syce4n	149	59	[	[	SYM
cord-301856-71syce4n	149	60	57	57	NUM
cord-301856-71syce4n	149	61	]	]	PUNCT
cord-301856-71syce4n	149	62	.	.	PUNCT
cord-301856-71syce4n	150	1	viruses	virus	NOUN
cord-301856-71syce4n	150	2	can	can	AUX
cord-301856-71syce4n	150	3	also	also	ADV
cord-301856-71syce4n	150	4	influence	influence	VERB
cord-301856-71syce4n	150	5	the	the	DET
cord-301856-71syce4n	150	6	severity	severity	NOUN
cord-301856-71syce4n	150	7	of	of	ADP
cord-301856-71syce4n	150	8	infections	infection	NOUN
cord-301856-71syce4n	150	9	caused	cause	VERB
cord-301856-71syce4n	150	10	by	by	ADP
cord-301856-71syce4n	150	11	other	other	ADJ
cord-301856-71syce4n	150	12	viruses	virus	NOUN
cord-301856-71syce4n	150	13	.	.	PUNCT
cord-301856-71syce4n	151	1	for	for	ADP
cord-301856-71syce4n	151	2	example	example	NOUN
cord-301856-71syce4n	151	3	,	,	PUNCT
cord-301856-71syce4n	151	4	cytomegalovirus	cytomegalovirus	PROPN
cord-301856-71syce4n	151	5	infection	infection	NOUN
cord-301856-71syce4n	151	6	in	in	ADP
cord-301856-71syce4n	151	7	hiv-1	hiv-1	PUNCT
cord-301856-71syce4n	151	8	seropositive	seropositive	ADJ
cord-301856-71syce4n	151	9	humans	human	NOUN
cord-301856-71syce4n	151	10	can	can	AUX
cord-301856-71syce4n	151	11	potentiate	potentiate	VERB
cord-301856-71syce4n	151	12	the	the	DET
cord-301856-71syce4n	151	13	effects	effect	NOUN
cord-301856-71syce4n	151	14	of	of	ADP
cord-301856-71syce4n	151	15	hiv-1	hiv-1	PUNCT
cord-301856-71syce4n	151	16	infection	infection	NOUN
cord-301856-71syce4n	151	17	by	by	ADP
cord-301856-71syce4n	151	18	expanding	expand	VERB
cord-301856-71syce4n	151	19	the	the	DET
cord-301856-71syce4n	151	20	pool	pool	NOUN
cord-301856-71syce4n	151	21	of	of	ADP
cord-301856-71syce4n	151	22	circulating	circulate	VERB
cord-301856-71syce4n	151	23	regulatory	regulatory	ADJ
cord-301856-71syce4n	151	24	t	t	NOUN
cord-301856-71syce4n	151	25	cells	cell	NOUN
cord-301856-71syce4n	151	26	(	(	PUNCT
cord-301856-71syce4n	151	27	immunosuppressive	immunosuppressive	NOUN
cord-301856-71syce4n	151	28	)	)	PUNCT
cord-301856-71syce4n	151	29	;	;	PUNCT
cord-301856-71syce4n	151	30	these	these	PRON
cord-301856-71syce4n	151	31	were	be	AUX
cord-301856-71syce4n	151	32	shown	show	VERB
cord-301856-71syce4n	151	33	to	to	PART
cord-301856-71syce4n	151	34	inhibit	inhibit	VERB
cord-301856-71syce4n	151	35	the	the	DET
cord-301856-71syce4n	151	36	proliferation	proliferation	NOUN
cord-301856-71syce4n	151	37	of	of	ADP
cord-301856-71syce4n	151	38	autologous	autologous	ADJ
cord-301856-71syce4n	151	39	peripheral	peripheral	ADJ
cord-301856-71syce4n	151	40	blood	blood	NOUN
cord-301856-71syce4n	151	41	mononuclear	mononuclear	ADJ
cord-301856-71syce4n	151	42	cell	cell	NOUN
cord-301856-71syce4n	151	43	the	the	DET
cord-301856-71syce4n	151	44	origins	origin	NOUN
cord-301856-71syce4n	151	45	of	of	ADP
cord-301856-71syce4n	151	46	the	the	DET
cord-301856-71syce4n	151	47	hiv	hiv	PROPN
cord-301856-71syce4n	151	48	virus	virus	NOUN
cord-301856-71syce4n	151	49	are	be	AUX
cord-301856-71syce4n	151	50	still	still	ADV
cord-301856-71syce4n	151	51	a	a	DET
cord-301856-71syce4n	151	52	matter	matter	NOUN
cord-301856-71syce4n	151	53	of	of	ADP
cord-301856-71syce4n	151	54	scientific	scientific	ADJ
cord-301856-71syce4n	151	55	discussion	discussion	NOUN
cord-301856-71syce4n	151	56	.	.	PUNCT
cord-301856-71syce4n	152	1	the	the	DET
cord-301856-71syce4n	152	2	most	most	ADV
cord-301856-71syce4n	152	3	accepted	accepted	ADJ
cord-301856-71syce4n	152	4	scenario	scenario	NOUN
cord-301856-71syce4n	152	5	argues	argue	VERB
cord-301856-71syce4n	152	6	that	that	SCONJ
cord-301856-71syce4n	152	7	hiv	hiv	PROPN
cord-301856-71syce4n	152	8	originated	originate	VERB
cord-301856-71syce4n	152	9	in	in	ADP
cord-301856-71syce4n	152	10	simians	simian	NOUN
cord-301856-71syce4n	152	11	and	and	CCONJ
cord-301856-71syce4n	152	12	was	be	AUX
cord-301856-71syce4n	152	13	transmitted	transmit	VERB
cord-301856-71syce4n	152	14	to	to	ADP
cord-301856-71syce4n	152	15	humans	human	NOUN
cord-301856-71syce4n	152	16	in	in	ADP
cord-301856-71syce4n	152	17	west	west	PROPN
cord-301856-71syce4n	152	18	africa	africa	PROPN
cord-301856-71syce4n	152	19	in	in	ADP
cord-301856-71syce4n	152	20	the	the	DET
cord-301856-71syce4n	152	21	1920s	1920s	NUM
cord-301856-71syce4n	152	22	,	,	PUNCT
cord-301856-71syce4n	152	23	likely	likely	ADJ
cord-301856-71syce4n	152	24	due	due	ADP
cord-301856-71syce4n	152	25	to	to	ADP
cord-301856-71syce4n	152	26	local	local	ADJ
cord-301856-71syce4n	152	27	ingestion	ingestion	NOUN
cord-301856-71syce4n	152	28	of	of	ADP
cord-301856-71syce4n	152	29	ape	ape	NOUN
cord-301856-71syce4n	152	30	meat	meat	NOUN
cord-301856-71syce4n	152	31	infected	infect	VERB
cord-301856-71syce4n	152	32	with	with	ADP
cord-301856-71syce4n	152	33	the	the	DET
cord-301856-71syce4n	152	34	simian	simian	ADJ
cord-301856-71syce4n	152	35	immunodeficiency	immunodeficiency	NOUN
cord-301856-71syce4n	152	36	virus	virus	NOUN
cord-301856-71syce4n	152	37	.	.	PUNCT
cord-301856-71syce4n	153	1	around	around	ADP
cord-301856-71syce4n	153	2	1960	1960	NUM
cord-301856-71syce4n	153	3	,	,	PUNCT
cord-301856-71syce4n	153	4	the	the	DET
cord-301856-71syce4n	153	5	virus	virus	NOUN
cord-301856-71syce4n	153	6	reached	reach	VERB
cord-301856-71syce4n	153	7	wide	wide	ADJ
cord-301856-71syce4n	153	8	parts	part	NOUN
cord-301856-71syce4n	153	9	of	of	ADP
cord-301856-71syce4n	153	10	the	the	DET
cord-301856-71syce4n	153	11	continent	continent	NOUN
cord-301856-71syce4n	153	12	and	and	CCONJ
cord-301856-71syce4n	153	13	finally	finally	ADV
cord-301856-71syce4n	153	14	spread	spread	VERB
cord-301856-71syce4n	153	15	overseas	overseas	ADJ
cord-301856-71syce4n	153	16	thanks	thank	NOUN
cord-301856-71syce4n	153	17	to	to	ADP
cord-301856-71syce4n	153	18	a	a	DET
cord-301856-71syce4n	153	19	group	group	NOUN
cord-301856-71syce4n	153	20	of	of	ADP
cord-301856-71syce4n	153	21	haitian	haitian	ADJ
cord-301856-71syce4n	153	22	professors	professor	NOUN
cord-301856-71syce4n	153	23	coming	come	VERB
cord-301856-71syce4n	153	24	back	back	ADV
cord-301856-71syce4n	153	25	from	from	ADP
cord-301856-71syce4n	153	26	africa	africa	PROPN
cord-301856-71syce4n	153	27	.	.	PUNCT
cord-301856-71syce4n	154	1	in	in	ADP
cord-301856-71syce4n	154	2	the	the	DET
cord-301856-71syce4n	154	3	following	follow	VERB
cord-301856-71syce4n	154	4	decades	decade	NOUN
cord-301856-71syce4n	154	5	,	,	PUNCT
cord-301856-71syce4n	154	6	the	the	DET
cord-301856-71syce4n	154	7	virus	virus	NOUN
cord-301856-71syce4n	154	8	spread	spread	VERB
cord-301856-71syce4n	154	9	worldwide	worldwide	ADV
cord-301856-71syce4n	154	10	and	and	CCONJ
cord-301856-71syce4n	154	11	generated	generate	VERB
cord-301856-71syce4n	154	12	the	the	DET
cord-301856-71syce4n	154	13	pandemic	pandemic	NOUN
cord-301856-71syce4n	154	14	we	we	PRON
cord-301856-71syce4n	154	15	now	now	ADV
cord-301856-71syce4n	154	16	know	know	VERB
cord-301856-71syce4n	154	17	.	.	PUNCT
cord-301856-71syce4n	155	1	today	today	NOUN
cord-301856-71syce4n	155	2	,	,	PUNCT
cord-301856-71syce4n	155	3	there	there	PRON
cord-301856-71syce4n	155	4	are	be	VERB
cord-301856-71syce4n	155	5	approximately	approximately	ADV
cord-301856-71syce4n	155	6	37	37	NUM
cord-301856-71syce4n	155	7	million	million	NUM
cord-301856-71syce4n	155	8	people	people	NOUN
cord-301856-71syce4n	155	9	worldwide	worldwide	ADV
cord-301856-71syce4n	155	10	living	live	VERB
cord-301856-71syce4n	155	11	with	with	ADP
cord-301856-71syce4n	155	12	hiv-1	hiv-1	SYM
cord-301856-71syce4n	155	13	/	/	SYM
cord-301856-71syce4n	155	14	aids	aid	NOUN
cord-301856-71syce4n	156	1	[	[	X
cord-301856-71syce4n	156	2	110	110	NUM
cord-301856-71syce4n	156	3	]	]	PUNCT
cord-301856-71syce4n	156	4	.	.	PUNCT
cord-301856-71syce4n	157	1	ccr5	ccr5	PROPN
cord-301856-71syce4n	157	2	is	be	AUX
cord-301856-71syce4n	157	3	a	a	DET
cord-301856-71syce4n	157	4	receptor	receptor	NOUN
cord-301856-71syce4n	157	5	of	of	ADP
cord-301856-71syce4n	157	6	chemokines	chemokine	NOUN
cord-301856-71syce4n	157	7	that	that	PRON
cord-301856-71syce4n	157	8	plays	play	VERB
cord-301856-71syce4n	157	9	a	a	DET
cord-301856-71syce4n	157	10	fundamental	fundamental	ADJ
cord-301856-71syce4n	157	11	role	role	NOUN
cord-301856-71syce4n	157	12	in	in	ADP
cord-301856-71syce4n	157	13	hiv-1	hiv-1	PUNCT
cord-301856-71syce4n	157	14	pathogenesis	pathogenesis	NOUN
cord-301856-71syce4n	157	15	and	and	CCONJ
cord-301856-71syce4n	157	16	it	it	PRON
cord-301856-71syce4n	157	17	is	be	AUX
cord-301856-71syce4n	157	18	also	also	ADV
cord-301856-71syce4n	157	19	one	one	NUM
cord-301856-71syce4n	157	20	of	of	ADP
cord-301856-71syce4n	157	21	the	the	DET
cord-301856-71syce4n	157	22	most	most	ADV
cord-301856-71syce4n	157	23	promising	promising	ADJ
cord-301856-71syce4n	157	24	targets	target	NOUN
cord-301856-71syce4n	157	25	to	to	PART
cord-301856-71syce4n	157	26	restrict	restrict	VERB
cord-301856-71syce4n	157	27	the	the	DET
cord-301856-71syce4n	157	28	infection	infection	NOUN
cord-301856-71syce4n	157	29	,	,	PUNCT
cord-301856-71syce4n	157	30	since	since	SCONJ
cord-301856-71syce4n	157	31	mutations	mutation	NOUN
cord-301856-71syce4n	157	32	in	in	ADP
cord-301856-71syce4n	157	33	this	this	DET
cord-301856-71syce4n	157	34	receptor	receptor	NOUN
cord-301856-71syce4n	157	35	turn	turn	VERB
cord-301856-71syce4n	157	36	individuals	individual	NOUN
cord-301856-71syce4n	157	37	resistant	resistant	ADJ
cord-301856-71syce4n	157	38	[	[	X
cord-301856-71syce4n	157	39	96	96	NUM
cord-301856-71syce4n	157	40	]	]	PUNCT
cord-301856-71syce4n	157	41	.	.	PUNCT
cord-301856-71syce4n	158	1	the	the	DET
cord-301856-71syce4n	158	2	ccr5	ccr5	PROPN
cord-301856-71syce4n	158	3	-	-	PUNCT
cord-301856-71syce4n	158	4	d32	d32	PROPN
cord-301856-71syce4n	158	5	mutation	mutation	NOUN
cord-301856-71syce4n	158	6	results	result	NOUN
cord-301856-71syce4n	158	7	in	in	ADP
cord-301856-71syce4n	158	8	a	a	DET
cord-301856-71syce4n	158	9	deletion	deletion	NOUN
cord-301856-71syce4n	158	10	that	that	PRON
cord-301856-71syce4n	158	11	eliminates	eliminate	VERB
cord-301856-71syce4n	158	12	the	the	DET
cord-301856-71syce4n	158	13	hiv-1	hiv-1	PUNCT
cord-301856-71syce4n	158	14	co	co	NOUN
cord-301856-71syce4n	158	15	-	-	NOUN
cord-301856-71syce4n	158	16	receptor	receptor	NOUN
cord-301856-71syce4n	158	17	on	on	ADP
cord-301856-71syce4n	158	18	lymphocytes	lymphocyte	NOUN
cord-301856-71syce4n	158	19	,	,	PUNCT
cord-301856-71syce4n	158	20	providing	provide	VERB
cord-301856-71syce4n	158	21	robust	robust	ADJ
cord-301856-71syce4n	158	22	protection	protection	NOUN
cord-301856-71syce4n	158	23	against	against	ADP
cord-301856-71syce4n	158	24	hiv-1	hiv-1	CCONJ
cord-301856-71syce4n	158	25	and	and	CCONJ
cord-301856-71syce4n	158	26	,	,	PUNCT
cord-301856-71syce4n	158	27	therefore	therefore	ADV
cord-301856-71syce4n	158	28	,	,	PUNCT
cord-301856-71syce4n	158	29	aids	aid	VERB
cord-301856-71syce4n	158	30	[	[	X
cord-301856-71syce4n	158	31	97	97	NUM
cord-301856-71syce4n	158	32	]	]	PUNCT
cord-301856-71syce4n	158	33	.	.	PUNCT
cord-301856-71syce4n	159	1	ccr5	ccr5	PROPN
cord-301856-71syce4n	159	2	-	-	PUNCT
cord-301856-71syce4n	159	3	d32	d32	PROPN
cord-301856-71syce4n	159	4	allele	allele	NOUN
cord-301856-71syce4n	159	5	frequencies	frequency	NOUN
cord-301856-71syce4n	159	6	reach	reach	VERB
cord-301856-71syce4n	159	7	14	14	NUM
cord-301856-71syce4n	159	8	%	%	NOUN
cord-301856-71syce4n	159	9	in	in	ADP
cord-301856-71syce4n	159	10	northern	northern	PROPN
cord-301856-71syce4n	159	11	europe	europe	PROPN
cord-301856-71syce4n	159	12	populations	population	NOUN
cord-301856-71syce4n	159	13	,	,	PUNCT
cord-301856-71syce4n	159	14	whereas	whereas	SCONJ
cord-301856-71syce4n	159	15	it	it	PRON
cord-301856-71syce4n	159	16	is	be	AUX
cord-301856-71syce4n	159	17	not	not	PART
cord-301856-71syce4n	159	18	present	present	ADJ
cord-301856-71syce4n	159	19	in	in	ADP
cord-301856-71syce4n	159	20	populations	population	NOUN
cord-301856-71syce4n	159	21	with	with	ADP
cord-301856-71syce4n	159	22	different	different	ADJ
cord-301856-71syce4n	159	23	ancestry	ancestry	NOUN
cord-301856-71syce4n	159	24	,	,	PUNCT
cord-301856-71syce4n	159	25	such	such	ADJ
cord-301856-71syce4n	159	26	as	as	ADP
cord-301856-71syce4n	159	27	east	east	PROPN
cord-301856-71syce4n	159	28	asian	asian	PROPN
cord-301856-71syce4n	159	29	,	,	PUNCT
cord-301856-71syce4n	159	30	native	native	ADJ
cord-301856-71syce4n	159	31	american	american	PROPN
cord-301856-71syce4n	159	32	,	,	PUNCT
cord-301856-71syce4n	159	33	or	or	CCONJ
cord-301856-71syce4n	159	34	african	african	ADJ
cord-301856-71syce4n	159	35	groups	group	NOUN
cord-301856-71syce4n	160	1	[	[	X
cord-301856-71syce4n	160	2	96	96	NUM
cord-301856-71syce4n	160	3	]	]	PUNCT
cord-301856-71syce4n	160	4	.	.	PUNCT
cord-301856-71syce4n	161	1	this	this	DET
cord-301856-71syce4n	161	2	regional	regional	ADJ
cord-301856-71syce4n	161	3	distribution	distribution	NOUN
cord-301856-71syce4n	161	4	of	of	ADP
cord-301856-71syce4n	161	5	ccr5	ccr5	PROPN
cord-301856-71syce4n	161	6	-	-	PUNCT
cord-301856-71syce4n	161	7	d32	d32	PROPN
cord-301856-71syce4n	161	8	variants	variant	NOUN
cord-301856-71syce4n	161	9	is	be	AUX
cord-301856-71syce4n	161	10	most	most	ADV
cord-301856-71syce4n	161	11	likely	likely	ADV
cord-301856-71syce4n	161	12	related	relate	VERB
cord-301856-71syce4n	161	13	to	to	ADP
cord-301856-71syce4n	161	14	a	a	DET
cord-301856-71syce4n	161	15	naturally	naturally	ADV
cord-301856-71syce4n	161	16	selective	selective	ADJ
cord-301856-71syce4n	161	17	episode	episode	NOUN
cord-301856-71syce4n	161	18	that	that	PRON
cord-301856-71syce4n	161	19	struck	strike	VERB
cord-301856-71syce4n	161	20	european	european	ADJ
cord-301856-71syce4n	161	21	populations	population	NOUN
cord-301856-71syce4n	161	22	around	around	ADP
cord-301856-71syce4n	161	23	700	700	NUM
cord-301856-71syce4n	161	24	years	year	NOUN
cord-301856-71syce4n	161	25	ago	ago	ADV
cord-301856-71syce4n	161	26	and	and	CCONJ
cord-301856-71syce4n	161	27	involved	involve	VERB
cord-301856-71syce4n	161	28	a	a	DET
cord-301856-71syce4n	161	29	strong	strong	ADJ
cord-301856-71syce4n	161	30	infectious	infectious	ADJ
cord-301856-71syce4n	161	31	agent	agent	NOUN
cord-301856-71syce4n	161	32	that	that	PRON
cord-301856-71syce4n	161	33	also	also	ADV
cord-301856-71syce4n	161	34	employed	employ	VERB
cord-301856-71syce4n	161	35	ccr5	ccr5	PROPN
cord-301856-71syce4n	161	36	[	[	PUNCT
cord-301856-71syce4n	161	37	98	98	NUM
cord-301856-71syce4n	161	38	]	]	PUNCT
cord-301856-71syce4n	161	39	.	.	PUNCT
cord-301856-71syce4n	162	1	a	a	DET
cord-301856-71syce4n	162	2	mathematical	mathematical	ADJ
cord-301856-71syce4n	162	3	model	model	NOUN
cord-301856-71syce4n	162	4	studying	study	VERB
cord-301856-71syce4n	162	5	the	the	DET
cord-301856-71syce4n	162	6	changes	change	NOUN
cord-301856-71syce4n	162	7	in	in	ADP
cord-301856-71syce4n	162	8	the	the	DET
cord-301856-71syce4n	162	9	european	european	ADJ
cord-301856-71syce4n	162	10	populations	population	NOUN
cord-301856-71syce4n	162	11	in	in	ADP
cord-301856-71syce4n	162	12	the	the	DET
cord-301856-71syce4n	162	13	middle	middle	ADJ
cord-301856-71syce4n	162	14	ages	age	NOUN
cord-301856-71syce4n	162	15	suggested	suggest	VERB
cord-301856-71syce4n	162	16	yersinia	yersinia	PROPN
cord-301856-71syce4n	162	17	pestis	pestis	PROPN
cord-301856-71syce4n	162	18	(	(	PUNCT
cord-301856-71syce4n	162	19	bubonic	bubonic	ADJ
cord-301856-71syce4n	162	20	plague	plague	NOUN
cord-301856-71syce4n	162	21	)	)	PUNCT
cord-301856-71syce4n	162	22	as	as	ADP
cord-301856-71syce4n	162	23	the	the	DET
cord-301856-71syce4n	162	24	most	most	ADV
cord-301856-71syce4n	162	25	probable	probable	ADJ
cord-301856-71syce4n	162	26	infectious	infectious	ADJ
cord-301856-71syce4n	162	27	agent	agent	NOUN
cord-301856-71syce4n	162	28	behind	behind	ADP
cord-301856-71syce4n	162	29	the	the	DET
cord-301856-71syce4n	162	30	pressure	pressure	NOUN
cord-301856-71syce4n	162	31	that	that	PRON
cord-301856-71syce4n	162	32	selected	select	VERB
cord-301856-71syce4n	162	33	this	this	DET
cord-301856-71syce4n	162	34	particular	particular	ADJ
cord-301856-71syce4n	162	35	genetic	genetic	ADJ
cord-301856-71syce4n	162	36	variant	variant	NOUN
cord-301856-71syce4n	162	37	[	[	X
cord-301856-71syce4n	162	38	99	99	NUM
cord-301856-71syce4n	162	39	]	]	PUNCT
cord-301856-71syce4n	162	40	.	.	PUNCT
cord-301856-71syce4n	163	1	this	this	PRON
cord-301856-71syce4n	163	2	is	be	AUX
cord-301856-71syce4n	163	3	in	in	ADP
cord-301856-71syce4n	163	4	agreement	agreement	NOUN
cord-301856-71syce4n	163	5	with	with	ADP
cord-301856-71syce4n	163	6	the	the	DET
cord-301856-71syce4n	163	7	finding	finding	NOUN
cord-301856-71syce4n	163	8	that	that	SCONJ
cord-301856-71syce4n	163	9	european	european	PROPN
cord-301856-71syce4n	163	10	rroma	rroma	PROPN
cord-301856-71syce4n	163	11	populations	population	NOUN
cord-301856-71syce4n	163	12	,	,	PUNCT
cord-301856-71syce4n	163	13	but	but	CCONJ
cord-301856-71syce4n	163	14	not	not	PART
cord-301856-71syce4n	163	15	northwestern	northwestern	PROPN
cord-301856-71syce4n	163	16	indian	indian	ADJ
cord-301856-71syce4n	163	17	populations	population	NOUN
cord-301856-71syce4n	163	18	that	that	PRON
cord-301856-71syce4n	163	19	inhabit	inhabit	VERB
cord-301856-71syce4n	163	20	the	the	DET
cord-301856-71syce4n	163	21	area	area	NOUN
cord-301856-71syce4n	163	22	where	where	SCONJ
cord-301856-71syce4n	163	23	the	the	DET
cord-301856-71syce4n	163	24	rroma	rroma	PROPN
cord-301856-71syce4n	163	25	originally	originally	ADV
cord-301856-71syce4n	163	26	lived	live	VERB
cord-301856-71syce4n	163	27	,	,	PUNCT
cord-301856-71syce4n	163	28	present	present	ADJ
cord-301856-71syce4n	163	29	signatures	signature	NOUN
cord-301856-71syce4n	163	30	of	of	ADP
cord-301856-71syce4n	163	31	positive	positive	ADJ
cord-301856-71syce4n	163	32	selection	selection	NOUN
cord-301856-71syce4n	163	33	in	in	ADP
cord-301856-71syce4n	163	34	tlr1	tlr1	PROPN
cord-301856-71syce4n	163	35	-	-	PUNCT
cord-301856-71syce4n	163	36	tlr6	tlr6	PROPN
cord-301856-71syce4n	163	37	-	-	PUNCT
cord-301856-71syce4n	163	38	tlr10	tlr10	PROPN
cord-301856-71syce4n	163	39	,	,	PUNCT
cord-301856-71syce4n	163	40	which	which	PRON
cord-301856-71syce4n	163	41	influence	influence	VERB
cord-301856-71syce4n	163	42	cytokine	cytokine	NOUN
cord-301856-71syce4n	163	43	responses	response	NOUN
cord-301856-71syce4n	163	44	in	in	ADP
cord-301856-71syce4n	163	45	y.	y.	PROPN
cord-301856-71syce4n	163	46	pestis	pestis	PROPN
cord-301856-71syce4n	163	47	infections	infection	NOUN
cord-301856-71syce4n	163	48	[	[	X
cord-301856-71syce4n	163	49	100	100	NUM
cord-301856-71syce4n	163	50	]	]	PUNCT
cord-301856-71syce4n	163	51	.	.	PUNCT
cord-301856-71syce4n	164	1	(	(	PUNCT
cord-301856-71syce4n	164	2	pbmc	pbmc	X
cord-301856-71syce4n	164	3	)	)	PUNCT
cord-301856-71syce4n	164	4	in	in	ADP
cord-301856-71syce4n	164	5	response	response	NOUN
cord-301856-71syce4n	164	6	to	to	ADP
cord-301856-71syce4n	164	7	cytomegalovirus	cytomegalovirus	PROPN
cord-301856-71syce4n	164	8	infection	infection	NOUN
cord-301856-71syce4n	164	9	in	in	ADP
cord-301856-71syce4n	164	10	vitro	vitro	X
cord-301856-71syce4n	165	1	[	[	X
cord-301856-71syce4n	165	2	58	58	NUM
cord-301856-71syce4n	165	3	]	]	PUNCT
cord-301856-71syce4n	165	4	.	.	PUNCT
cord-301856-71syce4n	166	1	in	in	ADP
cord-301856-71syce4n	166	2	one	one	NUM
cord-301856-71syce4n	166	3	study	study	NOUN
cord-301856-71syce4n	166	4	,	,	PUNCT
cord-301856-71syce4n	166	5	patients	patient	NOUN
cord-301856-71syce4n	166	6	with	with	ADP
cord-301856-71syce4n	166	7	chronic	chronic	PROPN
cord-301856-71syce4n	166	8	hepatitis	hepatitis	PROPN
cord-301856-71syce4n	166	9	c	c	PROPN
cord-301856-71syce4n	166	10	virus	virus	PROPN
cord-301856-71syce4n	166	11	(	(	PUNCT
cord-301856-71syce4n	166	12	hcv	hcv	PROPN
cord-301856-71syce4n	166	13	)	)	PUNCT
cord-301856-71syce4n	166	14	infection	infection	NOUN
cord-301856-71syce4n	166	15	and	and	CCONJ
cord-301856-71syce4n	166	16	hepatitis	hepatitis	NOUN
cord-301856-71syce4n	166	17	a	a	DET
cord-301856-71syce4n	166	18	virus	virus	NOUN
cord-301856-71syce4n	166	19	(	(	PUNCT
cord-301856-71syce4n	166	20	hav	hav	PROPN
cord-301856-71syce4n	166	21	)	)	PUNCT
cord-301856-71syce4n	166	22	superinfection	superinfection	NOUN
cord-301856-71syce4n	166	23	presented	present	VERB
cord-301856-71syce4n	166	24	lower	low	ADJ
cord-301856-71syce4n	166	25	titers	titer	NOUN
cord-301856-71syce4n	166	26	of	of	ADP
cord-301856-71syce4n	166	27	hcv	hcv	PROPN
cord-301856-71syce4n	166	28	rna	rna	PROPN
cord-301856-71syce4n	166	29	than	than	SCONJ
cord-301856-71syce4n	166	30	patients	patient	NOUN
cord-301856-71syce4n	166	31	harboring	harbor	VERB
cord-301856-71syce4n	166	32	only	only	ADV
cord-301856-71syce4n	166	33	hcv	hcv	PROPN
cord-301856-71syce4n	166	34	,	,	PUNCT
cord-301856-71syce4n	166	35	suggesting	suggest	VERB
cord-301856-71syce4n	166	36	that	that	SCONJ
cord-301856-71syce4n	166	37	hcv	hcv	ADJ
cord-301856-71syce4n	166	38	replication	replication	NOUN
cord-301856-71syce4n	166	39	might	might	AUX
cord-301856-71syce4n	166	40	be	be	AUX
cord-301856-71syce4n	166	41	potentially	potentially	ADV
cord-301856-71syce4n	166	42	suppressed	suppress	VERB
cord-301856-71syce4n	166	43	during	during	ADP
cord-301856-71syce4n	166	44	hav	hav	PROPN
cord-301856-71syce4n	166	45	infection	infection	NOUN
cord-301856-71syce4n	166	46	[	[	X
cord-301856-71syce4n	166	47	59	59	NUM
cord-301856-71syce4n	166	48	]	]	PUNCT
cord-301856-71syce4n	166	49	,	,	PUNCT
cord-301856-71syce4n	166	50	although	although	SCONJ
cord-301856-71syce4n	166	51	this	this	PRON
cord-301856-71syce4n	166	52	will	will	AUX
cord-301856-71syce4n	166	53	still	still	ADV
cord-301856-71syce4n	166	54	require	require	VERB
cord-301856-71syce4n	166	55	further	further	ADJ
cord-301856-71syce4n	166	56	investigation	investigation	NOUN
cord-301856-71syce4n	166	57	.	.	PUNCT
cord-301856-71syce4n	167	1	the	the	DET
cord-301856-71syce4n	167	2	relationships	relationship	NOUN
cord-301856-71syce4n	167	3	between	between	ADP
cord-301856-71syce4n	167	4	humans	human	NOUN
cord-301856-71syce4n	167	5	and	and	CCONJ
cord-301856-71syce4n	167	6	pathogenic	pathogenic	ADJ
cord-301856-71syce4n	167	7	or	or	CCONJ
cord-301856-71syce4n	167	8	nonpathogenic	nonpathogenic	ADJ
cord-301856-71syce4n	167	9	organisms	organism	NOUN
cord-301856-71syce4n	167	10	are	be	AUX
cord-301856-71syce4n	167	11	extraordinarily	extraordinarily	ADV
cord-301856-71syce4n	167	12	complex	complex	ADJ
cord-301856-71syce4n	167	13	and	and	CCONJ
cord-301856-71syce4n	167	14	include	include	VERB
cord-301856-71syce4n	167	15	tripartite	tripartite	ADJ
cord-301856-71syce4n	167	16	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	167	17	interactions	interaction	NOUN
cord-301856-71syce4n	167	18	between	between	ADP
cord-301856-71syce4n	167	19	humans	human	NOUN
cord-301856-71syce4n	167	20	and	and	CCONJ
cord-301856-71syce4n	167	21	microbes	microbe	NOUN
cord-301856-71syce4n	167	22	competing	compete	VERB
cord-301856-71syce4n	167	23	with	with	ADP
cord-301856-71syce4n	167	24	each	each	DET
cord-301856-71syce4n	167	25	other	other	ADJ
cord-301856-71syce4n	167	26	.	.	PUNCT
cord-301856-71syce4n	168	1	this	this	PRON
cord-301856-71syce4n	168	2	is	be	AUX
cord-301856-71syce4n	168	3	the	the	DET
cord-301856-71syce4n	168	4	case	case	NOUN
cord-301856-71syce4n	168	5	of	of	ADP
cord-301856-71syce4n	168	6	parasites	parasite	NOUN
cord-301856-71syce4n	168	7	that	that	PRON
cord-301856-71syce4n	168	8	infect	infect	VERB
cord-301856-71syce4n	168	9	other	other	ADJ
cord-301856-71syce4n	168	10	parasites	parasite	NOUN
cord-301856-71syce4n	168	11	,	,	PUNCT
cord-301856-71syce4n	168	12	such	such	ADJ
cord-301856-71syce4n	168	13	as	as	ADP
cord-301856-71syce4n	168	14	bacteriophage	bacteriophage	NOUN
cord-301856-71syce4n	168	15	viruses	virus	NOUN
cord-301856-71syce4n	168	16	,	,	PUNCT
cord-301856-71syce4n	168	17	that	that	PRON
cord-301856-71syce4n	168	18	can	can	AUX
cord-301856-71syce4n	168	19	influence	influence	VERB
cord-301856-71syce4n	168	20	the	the	DET
cord-301856-71syce4n	168	21	outcome	outcome	NOUN
cord-301856-71syce4n	168	22	of	of	ADP
cord-301856-71syce4n	168	23	bacterial	bacterial	ADJ
cord-301856-71syce4n	168	24	infections	infection	NOUN
cord-301856-71syce4n	168	25	.	.	PUNCT
cord-301856-71syce4n	169	1	for	for	ADP
cord-301856-71syce4n	169	2	example	example	NOUN
cord-301856-71syce4n	169	3	,	,	PUNCT
cord-301856-71syce4n	169	4	in	in	ADP
cord-301856-71syce4n	169	5	a	a	DET
cord-301856-71syce4n	169	6	cohort	cohort	NOUN
cord-301856-71syce4n	169	7	of	of	ADP
cord-301856-71syce4n	169	8	individuals	individual	NOUN
cord-301856-71syce4n	169	9	with	with	ADP
cord-301856-71syce4n	169	10	chronic	chronic	ADJ
cord-301856-71syce4n	169	11	wounds	wound	NOUN
cord-301856-71syce4n	169	12	,	,	PUNCT
cord-301856-71syce4n	169	13	a	a	DET
cord-301856-71syce4n	169	14	report	report	NOUN
cord-301856-71syce4n	169	15	showed	show	VERB
cord-301856-71syce4n	169	16	that	that	SCONJ
cord-301856-71syce4n	169	17	the	the	DET
cord-301856-71syce4n	169	18	phage	phage	NOUN
cord-301856-71syce4n	169	19	pf	pf	NOUN
cord-301856-71syce4n	169	20	,	,	PUNCT
cord-301856-71syce4n	169	21	which	which	PRON
cord-301856-71syce4n	169	22	coexists	coexist	VERB
cord-301856-71syce4n	169	23	with	with	ADP
cord-301856-71syce4n	169	24	pseudomonas	pseudomonas	PROPN
cord-301856-71syce4n	169	25	aeruginosa	aeruginosa	PROPN
cord-301856-71syce4n	169	26	in	in	ADP
cord-301856-71syce4n	169	27	infected	infected	ADJ
cord-301856-71syce4n	169	28	wounds	wound	NOUN
cord-301856-71syce4n	169	29	,	,	PUNCT
cord-301856-71syce4n	169	30	triggered	trigger	VERB
cord-301856-71syce4n	169	31	the	the	DET
cord-301856-71syce4n	169	32	production	production	NOUN
cord-301856-71syce4n	169	33	of	of	ADP
cord-301856-71syce4n	169	34	type	type	NOUN
cord-301856-71syce4n	169	35	i	i	PRON
cord-301856-71syce4n	169	36	ifn	ifn	NOUN
cord-301856-71syce4n	169	37	,	,	PUNCT
cord-301856-71syce4n	169	38	the	the	DET
cord-301856-71syce4n	169	39	inhibition	inhibition	NOUN
cord-301856-71syce4n	169	40	of	of	ADP
cord-301856-71syce4n	169	41	tumor	tumor	NOUN
cord-301856-71syce4n	169	42	necrosis	necrosis	NOUN
cord-301856-71syce4n	169	43	factor	factor	NOUN
cord-301856-71syce4n	169	44	(	(	PUNCT
cord-301856-71syce4n	169	45	tnf	tnf	PROPN
cord-301856-71syce4n	169	46	)	)	PUNCT
cord-301856-71syce4n	169	47	production	production	NOUN
cord-301856-71syce4n	169	48	,	,	PUNCT
cord-301856-71syce4n	169	49	and	and	CCONJ
cord-301856-71syce4n	169	50	the	the	DET
cord-301856-71syce4n	169	51	suppression	suppression	NOUN
cord-301856-71syce4n	169	52	of	of	ADP
cord-301856-71syce4n	169	53	phagocytosis	phagocytosis	NOUN
cord-301856-71syce4n	169	54	in	in	ADP
cord-301856-71syce4n	169	55	human	human	ADJ
cord-301856-71syce4n	169	56	primary	primary	ADJ
cord-301856-71syce4n	169	57	monocytes	monocyte	NOUN
cord-301856-71syce4n	169	58	and	and	CCONJ
cord-301856-71syce4n	169	59	mouse	mouse	NOUN
cord-301856-71syce4n	169	60	bone	bone	NOUN
cord-301856-71syce4n	169	61	marrow	marrow	NOUN
cord-301856-71syce4n	169	62	-	-	PUNCT
cord-301856-71syce4n	169	63	derived	derive	VERB
cord-301856-71syce4n	169	64	macrophages	macrophage	NOUN
cord-301856-71syce4n	169	65	,	,	PUNCT
cord-301856-71syce4n	169	66	dampening	dampen	VERB
cord-301856-71syce4n	169	67	the	the	DET
cord-301856-71syce4n	169	68	antibacterial	antibacterial	ADJ
cord-301856-71syce4n	169	69	response	response	NOUN
cord-301856-71syce4n	169	70	and	and	CCONJ
cord-301856-71syce4n	169	71	promoting	promote	VERB
cord-301856-71syce4n	169	72	the	the	DET
cord-301856-71syce4n	169	73	bacterial	bacterial	ADJ
cord-301856-71syce4n	169	74	infection	infection	NOUN
cord-301856-71syce4n	169	75	[	[	X
cord-301856-71syce4n	169	76	60	60	NUM
cord-301856-71syce4n	169	77	]	]	PUNCT
cord-301856-71syce4n	169	78	.	.	PUNCT
cord-301856-71syce4n	170	1	however	however	ADV
cord-301856-71syce4n	170	2	,	,	PUNCT
cord-301856-71syce4n	170	3	bacteriophages	bacteriophage	NOUN
cord-301856-71syce4n	170	4	can	can	AUX
cord-301856-71syce4n	170	5	also	also	ADV
cord-301856-71syce4n	170	6	provide	provide	VERB
cord-301856-71syce4n	170	7	protection	protection	NOUN
cord-301856-71syce4n	170	8	to	to	ADP
cord-301856-71syce4n	170	9	the	the	DET
cord-301856-71syce4n	170	10	human	human	ADJ
cord-301856-71syce4n	170	11	host	host	NOUN
cord-301856-71syce4n	170	12	by	by	ADP
cord-301856-71syce4n	170	13	directly	directly	ADV
cord-301856-71syce4n	170	14	attacking	attack	VERB
cord-301856-71syce4n	170	15	pathogenic	pathogenic	ADJ
cord-301856-71syce4n	170	16	bacteria	bacteria	NOUN
cord-301856-71syce4n	170	17	and	and	CCONJ
cord-301856-71syce4n	170	18	by	by	ADP
cord-301856-71syce4n	170	19	upregulating	upregulate	VERB
cord-301856-71syce4n	170	20	in	in	ADP
cord-301856-71syce4n	170	21	human	human	ADJ
cord-301856-71syce4n	170	22	pbmcs	pbmcs	PROPN
cord-301856-71syce4n	170	23	the	the	DET
cord-301856-71syce4n	170	24	expression	expression	NOUN
cord-301856-71syce4n	170	25	of	of	ADP
cord-301856-71syce4n	170	26	proinflammatory	proinflammatory	ADJ
cord-301856-71syce4n	170	27	genes	gene	NOUN
cord-301856-71syce4n	170	28	such	such	ADJ
cord-301856-71syce4n	170	29	as	as	ADP
cord-301856-71syce4n	170	30	il1a	il1a	PROPN
cord-301856-71syce4n	170	31	,	,	PUNCT
cord-301856-71syce4n	170	32	il1b	il1b	NOUN
cord-301856-71syce4n	170	33	,	,	PUNCT
cord-301856-71syce4n	170	34	il6	il6	NOUN
cord-301856-71syce4n	170	35	,	,	PUNCT
cord-301856-71syce4n	170	36	tnfa	tnfa	PROPN
cord-301856-71syce4n	170	37	,	,	PUNCT
cord-301856-71syce4n	170	38	cxcl1	cxcl1	PROPN
cord-301856-71syce4n	170	39	,	,	PUNCT
cord-301856-71syce4n	170	40	and	and	CCONJ
cord-301856-71syce4n	170	41	cxcl5	cxcl5	PROPN
cord-301856-71syce4n	170	42	,	,	PUNCT
cord-301856-71syce4n	170	43	as	as	SCONJ
cord-301856-71syce4n	170	44	shown	show	VERB
cord-301856-71syce4n	170	45	for	for	ADP
cord-301856-71syce4n	170	46	several	several	ADJ
cord-301856-71syce4n	170	47	s.	s.	PROPN
cord-301856-71syce4n	170	48	aureus	aureus	PROPN
cord-301856-71syce4n	170	49	and	and	CCONJ
cord-301856-71syce4n	170	50	p.	p.	PROPN
cord-301856-71syce4n	170	51	aeruginosa	aeruginosa	PROPN
cord-301856-71syce4n	170	52	phages	phage	NOUN
cord-301856-71syce4n	170	53	,	,	PUNCT
cord-301856-71syce4n	170	54	including	include	VERB
cord-301856-71syce4n	170	55	pnm	pnm	NOUN
cord-301856-71syce4n	170	56	,	,	PUNCT
cord-301856-71syce4n	170	57	luz19	luz19	PROPN
cord-301856-71syce4n	170	58	,	,	PUNCT
cord-301856-71syce4n	170	59	14	14	NUM
cord-301856-71syce4n	170	60	-	-	SYM
cord-301856-71syce4n	170	61	1	1	NUM
cord-301856-71syce4n	170	62	,	,	PUNCT
cord-301856-71syce4n	170	63	and	and	CCONJ
cord-301856-71syce4n	170	64	ge	ge	PROPN
cord-301856-71syce4n	170	65	-	-	PUNCT
cord-301856-71syce4n	170	66	vb_pae	vb_pae	PROPN
cord-301856-71syce4n	170	67	-	-	PUNCT
cord-301856-71syce4n	170	68	kakheti25	kakheti25	NOUN
cord-301856-71syce4n	171	1	[	[	PUNCT
cord-301856-71syce4n	171	2	61	61	NUM
cord-301856-71syce4n	171	3	]	]	PUNCT
cord-301856-71syce4n	171	4	.	.	PUNCT
cord-301856-71syce4n	172	1	cooperative	cooperative	ADJ
cord-301856-71syce4n	172	2	relationships	relationship	NOUN
cord-301856-71syce4n	172	3	between	between	ADP
cord-301856-71syce4n	172	4	organisms	organism	NOUN
cord-301856-71syce4n	172	5	are	be	AUX
cord-301856-71syce4n	172	6	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	172	7	processes	process	NOUN
cord-301856-71syce4n	172	8	themselves	themselves	PRON
cord-301856-71syce4n	172	9	.	.	PUNCT
cord-301856-71syce4n	173	1	the	the	DET
cord-301856-71syce4n	173	2	way	way	NOUN
cord-301856-71syce4n	173	3	microorganisms	microorganism	NOUN
cord-301856-71syce4n	173	4	and	and	CCONJ
cord-301856-71syce4n	173	5	their	their	PRON
cord-301856-71syce4n	173	6	hosts	host	NOUN
cord-301856-71syce4n	173	7	associate	associate	NOUN
cord-301856-71syce4n	173	8	can	can	AUX
cord-301856-71syce4n	173	9	lead	lead	VERB
cord-301856-71syce4n	173	10	to	to	ADP
cord-301856-71syce4n	173	11	interactions	interaction	NOUN
cord-301856-71syce4n	173	12	of	of	ADP
cord-301856-71syce4n	173	13	mutualism	mutualism	NOUN
cord-301856-71syce4n	173	14	,	,	PUNCT
cord-301856-71syce4n	173	15	in	in	ADP
cord-301856-71syce4n	173	16	which	which	PRON
cord-301856-71syce4n	173	17	the	the	DET
cord-301856-71syce4n	173	18	interplay	interplay	NOUN
cord-301856-71syce4n	173	19	may	may	AUX
cord-301856-71syce4n	173	20	be	be	AUX
cord-301856-71syce4n	173	21	so	so	ADV
cord-301856-71syce4n	173	22	intimate	intimate	ADJ
cord-301856-71syce4n	173	23	as	as	SCONJ
cord-301856-71syce4n	173	24	to	to	PART
cord-301856-71syce4n	173	25	provide	provide	VERB
cord-301856-71syce4n	173	26	benefit	benefit	NOUN
cord-301856-71syce4n	173	27	for	for	ADP
cord-301856-71syce4n	173	28	each	each	DET
cord-301856-71syce4n	173	29	party	party	NOUN
cord-301856-71syce4n	173	30	and	and	CCONJ
cord-301856-71syce4n	173	31	influence	influence	VERB
cord-301856-71syce4n	173	32	immune	immune	ADJ
cord-301856-71syce4n	173	33	responses	response	NOUN
cord-301856-71syce4n	173	34	against	against	ADP
cord-301856-71syce4n	173	35	different	different	ADJ
cord-301856-71syce4n	173	36	types	type	NOUN
cord-301856-71syce4n	173	37	of	of	ADP
cord-301856-71syce4n	173	38	pathogens	pathogen	NOUN
cord-301856-71syce4n	173	39	.	.	PUNCT
cord-301856-71syce4n	174	1	a	a	DET
cord-301856-71syce4n	174	2	great	great	ADJ
cord-301856-71syce4n	174	3	number	number	NOUN
cord-301856-71syce4n	174	4	of	of	ADP
cord-301856-71syce4n	174	5	humans	human	NOUN
cord-301856-71syce4n	174	6	live	live	VERB
cord-301856-71syce4n	174	7	far	far	ADV
cord-301856-71syce4n	174	8	away	away	ADV
cord-301856-71syce4n	174	9	from	from	ADP
cord-301856-71syce4n	174	10	the	the	DET
cord-301856-71syce4n	174	11	original	original	ADJ
cord-301856-71syce4n	174	12	settlements	settlement	NOUN
cord-301856-71syce4n	174	13	of	of	ADP
cord-301856-71syce4n	174	14	their	their	PRON
cord-301856-71syce4n	174	15	ancestors	ancestor	NOUN
cord-301856-71syce4n	174	16	and	and	CCONJ
cord-301856-71syce4n	174	17	are	be	AUX
cord-301856-71syce4n	174	18	subject	subject	ADJ
cord-301856-71syce4n	174	19	to	to	ADP
cord-301856-71syce4n	174	20	radically	radically	ADV
cord-301856-71syce4n	174	21	different	different	ADJ
cord-301856-71syce4n	174	22	environmental	environmental	ADJ
cord-301856-71syce4n	174	23	conditions	condition	NOUN
cord-301856-71syce4n	174	24	.	.	PUNCT
cord-301856-71syce4n	175	1	between	between	ADP
cord-301856-71syce4n	175	2	two	two	NUM
cord-301856-71syce4n	175	3	and	and	CCONJ
cord-301856-71syce4n	175	4	three	three	NUM
cord-301856-71syce4n	175	5	million	million	NUM
cord-301856-71syce4n	175	6	people	people	NOUN
cord-301856-71syce4n	175	7	with	with	ADP
cord-301856-71syce4n	175	8	european	european	PROPN
cord-301856-71syce4n	175	9	genealogy	genealogy	PROPN
cord-301856-71syce4n	175	10	suffer	suffer	VERB
cord-301856-71syce4n	175	11	from	from	ADP
cord-301856-71syce4n	175	12	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	175	13	diseases	disease	NOUN
cord-301856-71syce4n	175	14	,	,	PUNCT
cord-301856-71syce4n	175	15	the	the	DET
cord-301856-71syce4n	175	16	prevalence	prevalence	NOUN
cord-301856-71syce4n	175	17	of	of	ADP
cord-301856-71syce4n	175	18	which	which	PRON
cord-301856-71syce4n	175	19	is	be	AUX
cord-301856-71syce4n	175	20	also	also	ADV
cord-301856-71syce4n	175	21	increasing	increase	VERB
cord-301856-71syce4n	175	22	in	in	ADP
cord-301856-71syce4n	175	23	other	other	ADJ
cord-301856-71syce4n	175	24	populations	population	NOUN
cord-301856-71syce4n	175	25	across	across	ADP
cord-301856-71syce4n	175	26	the	the	DET
cord-301856-71syce4n	175	27	globe	globe	NOUN
cord-301856-71syce4n	175	28	[	[	PUNCT
cord-301856-71syce4n	175	29	62	62	NUM
cord-301856-71syce4n	175	30	]	]	PUNCT
cord-301856-71syce4n	175	31	.	.	PUNCT
cord-301856-71syce4n	176	1	there	there	PRON
cord-301856-71syce4n	176	2	is	be	VERB
cord-301856-71syce4n	176	3	rising	rise	VERB
cord-301856-71syce4n	176	4	evidence	evidence	NOUN
cord-301856-71syce4n	176	5	that	that	SCONJ
cord-301856-71syce4n	176	6	the	the	DET
cord-301856-71syce4n	176	7	emergence	emergence	NOUN
cord-301856-71syce4n	176	8	of	of	ADP
cord-301856-71syce4n	176	9	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	176	10	diseases	disease	NOUN
cord-301856-71syce4n	176	11	is	be	AUX
cord-301856-71syce4n	176	12	associated	associate	VERB
cord-301856-71syce4n	176	13	with	with	ADP
cord-301856-71syce4n	176	14	the	the	DET
cord-301856-71syce4n	176	15	presence	presence	NOUN
cord-301856-71syce4n	176	16	of	of	ADP
cord-301856-71syce4n	176	17	a	a	DET
cord-301856-71syce4n	176	18	number	number	NOUN
cord-301856-71syce4n	176	19	of	of	ADP
cord-301856-71syce4n	176	20	immune	immune	NOUN
cord-301856-71syce4n	176	21	-	-	PUNCT
cord-301856-71syce4n	176	22	related	relate	VERB
cord-301856-71syce4n	176	23	alleles	allele	NOUN
cord-301856-71syce4n	176	24	that	that	PRON
cord-301856-71syce4n	176	25	have	have	AUX
cord-301856-71syce4n	176	26	been	be	AUX
cord-301856-71syce4n	176	27	selected	select	VERB
cord-301856-71syce4n	176	28	via	via	ADP
cord-301856-71syce4n	176	29	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	176	30	processes	process	NOUN
cord-301856-71syce4n	176	31	;	;	PUNCT
cord-301856-71syce4n	176	32	and	and	CCONJ
cord-301856-71syce4n	176	33	,	,	PUNCT
cord-301856-71syce4n	176	34	furthermore	furthermore	ADV
cord-301856-71syce4n	176	35	,	,	PUNCT
cord-301856-71syce4n	176	36	that	that	SCONJ
cord-301856-71syce4n	176	37	the	the	DET
cord-301856-71syce4n	176	38	contrasting	contrast	VERB
cord-301856-71syce4n	176	39	differences	difference	NOUN
cord-301856-71syce4n	176	40	in	in	ADP
cord-301856-71syce4n	176	41	the	the	DET
cord-301856-71syce4n	176	42	prevalence	prevalence	NOUN
cord-301856-71syce4n	176	43	of	of	ADP
cord-301856-71syce4n	176	44	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	176	45	diseases	disease	NOUN
cord-301856-71syce4n	176	46	between	between	ADP
cord-301856-71syce4n	176	47	populations	population	NOUN
cord-301856-71syce4n	176	48	may	may	AUX
cord-301856-71syce4n	176	49	be	be	AUX
cord-301856-71syce4n	176	50	a	a	DET
cord-301856-71syce4n	176	51	result	result	NOUN
cord-301856-71syce4n	176	52	of	of	ADP
cord-301856-71syce4n	176	53	different	different	ADJ
cord-301856-71syce4n	176	54	selective	selective	ADJ
cord-301856-71syce4n	176	55	pressures	pressure	NOUN
cord-301856-71syce4n	176	56	[	[	X
cord-301856-71syce4n	176	57	63	63	NUM
cord-301856-71syce4n	176	58	]	]	PUNCT
cord-301856-71syce4n	176	59	.	.	PUNCT
cord-301856-71syce4n	177	1	alleles	allele	NOUN
cord-301856-71syce4n	177	2	associated	associate	VERB
cord-301856-71syce4n	177	3	with	with	ADP
cord-301856-71syce4n	177	4	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	177	5	diseases	disease	NOUN
cord-301856-71syce4n	177	6	that	that	PRON
cord-301856-71syce4n	177	7	present	present	ADJ
cord-301856-71syce4n	177	8	marks	mark	NOUN
cord-301856-71syce4n	177	9	of	of	ADP
cord-301856-71syce4n	177	10	modern	modern	ADJ
cord-301856-71syce4n	177	11	positive	positive	ADJ
cord-301856-71syce4n	177	12	selection	selection	NOUN
cord-301856-71syce4n	177	13	include	include	VERB
cord-301856-71syce4n	177	14	the	the	DET
cord-301856-71syce4n	177	15	risk	risk	NOUN
cord-301856-71syce4n	177	16	allele	allele	NOUN
cord-301856-71syce4n	177	17	fut2	fut2	NOUN
cord-301856-71syce4n	177	18	at	at	ADP
cord-301856-71syce4n	177	19	rs601338	rs601338	PROPN
cord-301856-71syce4n	177	20	for	for	ADP
cord-301856-71syce4n	177	21	crohn	crohn	PROPN
cord-301856-71syce4n	177	22	's	's	PART
cord-301856-71syce4n	177	23	disease	disease	NOUN
cord-301856-71syce4n	177	24	(	(	PUNCT
cord-301856-71syce4n	177	25	cd	cd	PROPN
cord-301856-71syce4n	177	26	)	)	PUNCT
cord-301856-71syce4n	177	27	or	or	CCONJ
cord-301856-71syce4n	177	28	the	the	DET
cord-301856-71syce4n	177	29	risk	risk	NOUN
cord-301856-71syce4n	177	30	variant	variant	NOUN
cord-301856-71syce4n	177	31	sh2b3	sh2b3	NOUN
cord-301856-71syce4n	177	32	at	at	ADP
cord-301856-71syce4n	177	33	rs3184504	rs3184504	PROPN
cord-301856-71syce4n	177	34	for	for	ADP
cord-301856-71syce4n	177	35	celiac	celiac	ADJ
cord-301856-71syce4n	177	36	disease	disease	NOUN
cord-301856-71syce4n	177	37	[	[	X
cord-301856-71syce4n	177	38	64	64	NUM
cord-301856-71syce4n	177	39	]	]	PUNCT
cord-301856-71syce4n	177	40	;	;	PUNCT
cord-301856-71syce4n	177	41	such	such	ADJ
cord-301856-71syce4n	177	42	variants	variant	NOUN
cord-301856-71syce4n	177	43	have	have	AUX
cord-301856-71syce4n	177	44	been	be	AUX
cord-301856-71syce4n	177	45	linked	link	VERB
cord-301856-71syce4n	177	46	to	to	ADP
cord-301856-71syce4n	177	47	the	the	DET
cord-301856-71syce4n	177	48	development	development	NOUN
cord-301856-71syce4n	177	49	of	of	ADP
cord-301856-71syce4n	177	50	several	several	ADJ
cord-301856-71syce4n	177	51	human	human	ADJ
cord-301856-71syce4n	177	52	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	177	53	diseases	disease	NOUN
cord-301856-71syce4n	177	54	,	,	PUNCT
cord-301856-71syce4n	177	55	such	such	ADJ
cord-301856-71syce4n	177	56	as	as	ADP
cord-301856-71syce4n	177	57	type	type	NOUN
cord-301856-71syce4n	177	58	1	1	NUM
cord-301856-71syce4n	177	59	diabetes	diabetes	NOUN
cord-301856-71syce4n	177	60	,	,	PUNCT
cord-301856-71syce4n	177	61	ms	ms	PROPN
cord-301856-71syce4n	177	62	,	,	PUNCT
cord-301856-71syce4n	177	63	and	and	CCONJ
cord-301856-71syce4n	177	64	celiac	celiac	ADJ
cord-301856-71syce4n	177	65	disease	disease	NOUN
cord-301856-71syce4n	177	66	[	[	PUNCT
cord-301856-71syce4n	177	67	64	64	NUM
cord-301856-71syce4n	177	68	,	,	PUNCT
cord-301856-71syce4n	177	69	65	65	NUM
cord-301856-71syce4n	177	70	]	]	PUNCT
cord-301856-71syce4n	177	71	.	.	PUNCT
cord-301856-71syce4n	178	1	the	the	DET
cord-301856-71syce4n	178	2	analysis	analysis	NOUN
cord-301856-71syce4n	178	3	of	of	ADP
cord-301856-71syce4n	178	4	the	the	DET
cord-301856-71syce4n	178	5	integrated	integrate	VERB
cord-301856-71syce4n	178	6	haplotype	haplotype	NOUN
cord-301856-71syce4n	178	7	score	score	NOUN
cord-301856-71syce4n	178	8	[	[	X
cord-301856-71syce4n	178	9	66	66	NUM
cord-301856-71syce4n	178	10	]	]	PUNCT
cord-301856-71syce4n	178	11	of	of	ADP
cord-301856-71syce4n	178	12	loci	loci	NOUN
cord-301856-71syce4n	178	13	associated	associate	VERB
cord-301856-71syce4n	178	14	with	with	ADP
cord-301856-71syce4n	178	15	sle	sle	PROPN
cord-301856-71syce4n	178	16	that	that	PRON
cord-301856-71syce4n	178	17	might	might	AUX
cord-301856-71syce4n	178	18	provide	provide	VERB
cord-301856-71syce4n	178	19	protection	protection	NOUN
cord-301856-71syce4n	178	20	against	against	ADP
cord-301856-71syce4n	178	21	infections	infection	NOUN
cord-301856-71syce4n	178	22	,	,	PUNCT
cord-301856-71syce4n	178	23	such	such	ADJ
cord-301856-71syce4n	178	24	as	as	ADP
cord-301856-71syce4n	178	25	tnip1	tnip1	PROPN
cord-301856-71syce4n	178	26	,	,	PUNCT
cord-301856-71syce4n	178	27	itgam	itgam	ADJ
cord-301856-71syce4n	178	28	,	,	PUNCT
cord-301856-71syce4n	178	29	ptpn22	ptpn22	NOUN
cord-301856-71syce4n	178	30	,	,	PUNCT
cord-301856-71syce4n	178	31	tnfsf4	tnfsf4	NOUN
cord-301856-71syce4n	178	32	,	,	PUNCT
cord-301856-71syce4n	178	33	uhrf1bp1	uhrf1bp1	NOUN
cord-301856-71syce4n	178	34	,	,	PUNCT
cord-301856-71syce4n	178	35	tet3	tet3	ADJ
cord-301856-71syce4n	178	36	-	-	PUNCT
cord-301856-71syce4n	178	37	dguok	dguok	NOUN
cord-301856-71syce4n	178	38	,	,	PUNCT
cord-301856-71syce4n	178	39	and	and	CCONJ
cord-301856-71syce4n	178	40	blk	blk	ADV
cord-301856-71syce4n	178	41	,	,	PUNCT
cord-301856-71syce4n	178	42	has	have	AUX
cord-301856-71syce4n	178	43	suggested	suggest	VERB
cord-301856-71syce4n	178	44	that	that	SCONJ
cord-301856-71syce4n	178	45	these	these	DET
cord-301856-71syce4n	178	46	loci	loci	NOUN
cord-301856-71syce4n	178	47	exhibit	exhibit	VERB
cord-301856-71syce4n	178	48	robust	robust	ADJ
cord-301856-71syce4n	178	49	signs	sign	NOUN
cord-301856-71syce4n	178	50	of	of	ADP
cord-301856-71syce4n	178	51	positive	positive	ADJ
cord-301856-71syce4n	178	52	selection	selection	NOUN
cord-301856-71syce4n	178	53	[	[	X
cord-301856-71syce4n	178	54	67	67	NUM
cord-301856-71syce4n	178	55	]	]	PUNCT
cord-301856-71syce4n	178	56	(	(	PUNCT
cord-301856-71syce4n	178	57	figure	figure	NOUN
cord-301856-71syce4n	178	58	4	4	NUM
cord-301856-71syce4n	178	59	,	,	PUNCT
cord-301856-71syce4n	178	60	key	key	ADJ
cord-301856-71syce4n	178	61	figure	figure	NOUN
cord-301856-71syce4n	178	62	and	and	CCONJ
cord-301856-71syce4n	178	63	table	table	NOUN
cord-301856-71syce4n	178	64	1	1	NUM
cord-301856-71syce4n	178	65	)	)	PUNCT
cord-301856-71syce4n	178	66	.	.	PUNCT
cord-301856-71syce4n	179	1	african	african	ADJ
cord-301856-71syce4n	179	2	and	and	CCONJ
cord-301856-71syce4n	179	3	asian	asian	ADJ
cord-301856-71syce4n	179	4	human	human	ADJ
cord-301856-71syce4n	179	5	populations	population	NOUN
cord-301856-71syce4n	179	6	exposed	expose	VERB
cord-301856-71syce4n	179	7	to	to	ADP
cord-301856-71syce4n	179	8	trypanosoma	trypanosoma	NOUN
cord-301856-71syce4n	179	9	brucei	brucei	NOUN
cord-301856-71syce4n	179	10	or	or	CCONJ
cord-301856-71syce4n	179	11	plasmodium	plasmodium	PROPN
cord-301856-71syce4n	179	12	sp	sp	NOUN
cord-301856-71syce4n	179	13	.	.	PROPN
cord-301856-71syce4n	179	14	have	have	AUX
cord-301856-71syce4n	179	15	presented	present	VERB
cord-301856-71syce4n	179	16	positive	positive	ADJ
cord-301856-71syce4n	179	17	selection	selection	NOUN
cord-301856-71syce4n	179	18	of	of	ADP
cord-301856-71syce4n	179	19	snps	snps	PROPN
cord-301856-71syce4n	179	20	in	in	ADP
cord-301856-71syce4n	179	21	the	the	DET
cord-301856-71syce4n	179	22	apol1	apol1	NOUN
cord-301856-71syce4n	179	23	and	and	CCONJ
cord-301856-71syce4n	179	24	fcgr2b	fcgr2b	NUM
cord-301856-71syce4n	179	25	genes	gene	NOUN
cord-301856-71syce4n	179	26	;	;	PUNCT
cord-301856-71syce4n	179	27	indeed	indeed	ADV
cord-301856-71syce4n	179	28	,	,	PUNCT
cord-301856-71syce4n	179	29	by	by	ADP
cord-301856-71syce4n	179	30	enhancing	enhance	VERB
cord-301856-71syce4n	179	31	human	human	ADJ
cord-301856-71syce4n	179	32	macrophage	macrophage	NOUN
cord-301856-71syce4n	179	33	-	-	PUNCT
cord-301856-71syce4n	179	34	mediated	mediate	VERB
cord-301856-71syce4n	179	35	phagocytosis	phagocytosis	NOUN
cord-301856-71syce4n	179	36	of	of	ADP
cord-301856-71syce4n	179	37	infected	infected	ADJ
cord-301856-71syce4n	179	38	erythrocytes	erythrocyte	NOUN
cord-301856-71syce4n	179	39	,	,	PUNCT
cord-301856-71syce4n	179	40	despite	despite	SCONJ
cord-301856-71syce4n	179	41	their	their	PRON
cord-301856-71syce4n	179	42	association	association	NOUN
cord-301856-71syce4n	179	43	with	with	ADP
cord-301856-71syce4n	179	44	an	an	DET
cord-301856-71syce4n	179	45	sle	sle	PROPN
cord-301856-71syce4n	179	46	predisposition	predisposition	NOUN
cord-301856-71syce4n	179	47	,	,	PUNCT
cord-301856-71syce4n	179	48	these	these	DET
cord-301856-71syce4n	179	49	snps	snps	PROPN
cord-301856-71syce4n	179	50	have	have	AUX
cord-301856-71syce4n	179	51	been	be	AUX
cord-301856-71syce4n	179	52	associated	associate	VERB
cord-301856-71syce4n	179	53	with	with	ADP
cord-301856-71syce4n	179	54	protective	protective	ADJ
cord-301856-71syce4n	179	55	roles	role	NOUN
cord-301856-71syce4n	179	56	against	against	ADP
cord-301856-71syce4n	179	57	sleeping	sleep	VERB
cord-301856-71syce4n	179	58	sickness	sickness	NOUN
cord-301856-71syce4n	179	59	and	and	CCONJ
cord-301856-71syce4n	179	60	malaria	malaria	NOUN
cord-301856-71syce4n	179	61	,	,	PUNCT
cord-301856-71syce4n	179	62	respectively	respectively	ADV
cord-301856-71syce4n	179	63	[	[	X
cord-301856-71syce4n	179	64	68	68	NUM
cord-301856-71syce4n	179	65	,	,	PUNCT
cord-301856-71syce4n	179	66	69	69	NUM
cord-301856-71syce4n	179	67	]	]	PUNCT
cord-301856-71syce4n	179	68	.	.	PUNCT
cord-301856-71syce4n	180	1	an	an	DET
cord-301856-71syce4n	180	2	analysis	analysis	NOUN
cord-301856-71syce4n	180	3	of	of	ADP
cord-301856-71syce4n	180	4	human	human	ADJ
cord-301856-71syce4n	180	5	loci	loci	NOUN
cord-301856-71syce4n	180	6	associated	associate	VERB
cord-301856-71syce4n	180	7	with	with	ADP
cord-301856-71syce4n	180	8	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	180	9	bowel	bowel	NOUN
cord-301856-71syce4n	180	10	disease	disease	NOUN
cord-301856-71syce4n	180	11	(	(	PUNCT
cord-301856-71syce4n	180	12	ibd	ibd	NOUN
cord-301856-71syce4n	180	13	)	)	PUNCT
cord-301856-71syce4n	180	14	concluded	conclude	VERB
cord-301856-71syce4n	180	15	that	that	SCONJ
cord-301856-71syce4n	180	16	the	the	DET
cord-301856-71syce4n	180	17	majority	majority	NOUN
cord-301856-71syce4n	180	18	of	of	ADP
cord-301856-71syce4n	180	19	the	the	DET
cord-301856-71syce4n	180	20	loci	loci	NOUN
cord-301856-71syce4n	180	21	associated	associate	VERB
cord-301856-71syce4n	180	22	with	with	ADP
cord-301856-71syce4n	180	23	cd	cd	PROPN
cord-301856-71syce4n	180	24	are	be	AUX
cord-301856-71syce4n	180	25	also	also	ADV
cord-301856-71syce4n	180	26	linked	link	VERB
cord-301856-71syce4n	180	27	with	with	ADP
cord-301856-71syce4n	180	28	a	a	DET
cord-301856-71syce4n	180	29	higher	high	ADJ
cord-301856-71syce4n	180	30	risk	risk	NOUN
cord-301856-71syce4n	180	31	of	of	ADP
cord-301856-71syce4n	180	32	developing	develop	VERB
cord-301856-71syce4n	180	33	ulcerative	ulcerative	ADJ
cord-301856-71syce4n	180	34	colitis	colitis	NOUN
cord-301856-71syce4n	181	1	[	[	X
cord-301856-71syce4n	181	2	70	70	NUM
cord-301856-71syce4n	181	3	]	]	PUNCT
cord-301856-71syce4n	181	4	(	(	PUNCT
cord-301856-71syce4n	181	5	table	table	NOUN
cord-301856-71syce4n	181	6	1	1	NUM
cord-301856-71syce4n	181	7	)	)	PUNCT
cord-301856-71syce4n	181	8	.	.	PUNCT
cord-301856-71syce4n	182	1	many	many	ADJ
cord-301856-71syce4n	182	2	of	of	ADP
cord-301856-71syce4n	182	3	these	these	DET
cord-301856-71syce4n	182	4	loci	loci	NOUN
cord-301856-71syce4n	182	5	were	be	AUX
cord-301856-71syce4n	182	6	also	also	ADV
cord-301856-71syce4n	182	7	associated	associate	VERB
cord-301856-71syce4n	182	8	with	with	ADP
cord-301856-71syce4n	182	9	the	the	DET
cord-301856-71syce4n	182	10	development	development	NOUN
cord-301856-71syce4n	182	11	of	of	ADP
cord-301856-71syce4n	182	12	other	other	ADJ
cord-301856-71syce4n	182	13	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	182	14	diseases	disease	NOUN
cord-301856-71syce4n	182	15	,	,	PUNCT
cord-301856-71syce4n	182	16	namely	namely	ADV
cord-301856-71syce4n	182	17	psoriasis	psoriasis	NOUN
cord-301856-71syce4n	182	18	and	and	CCONJ
cord-301856-71syce4n	182	19	ankylosing	ankylose	VERB
cord-301856-71syce4n	182	20	spondylitis	spondylitis	NOUN
cord-301856-71syce4n	182	21	[	[	X
cord-301856-71syce4n	182	22	62	62	NUM
cord-301856-71syce4n	182	23	]	]	PUNCT
cord-301856-71syce4n	182	24	.	.	PUNCT
cord-301856-71syce4n	183	1	pbmcs	pbmcs	PROPN
cord-301856-71syce4n	183	2	from	from	ADP
cord-301856-71syce4n	183	3	individuals	individual	NOUN
cord-301856-71syce4n	183	4	carrying	carry	VERB
cord-301856-71syce4n	183	5	the	the	DET
cord-301856-71syce4n	183	6	sh2b3	sh2b3	NOUN
cord-301856-71syce4n	183	7	variant	variant	NOUN
cord-301856-71syce4n	183	8	rs3184504*a	rs3184504*a	NOUN
cord-301856-71syce4n	183	9	(	(	PUNCT
cord-301856-71syce4n	183	10	associated	associate	VERB
cord-301856-71syce4n	183	11	with	with	ADP
cord-301856-71syce4n	183	12	a	a	DET
cord-301856-71syce4n	183	13	risk	risk	NOUN
cord-301856-71syce4n	183	14	for	for	ADP
cord-301856-71syce4n	183	15	developing	develop	VERB
cord-301856-71syce4n	183	16	cd	cd	NOUN
cord-301856-71syce4n	183	17	)	)	PUNCT
cord-301856-71syce4n	183	18	[	[	X
cord-301856-71syce4n	183	19	71	71	NUM
cord-301856-71syce4n	183	20	]	]	PUNCT
cord-301856-71syce4n	183	21	presented	present	VERB
cord-301856-71syce4n	183	22	higher	high	ADJ
cord-301856-71syce4n	183	23	production	production	NOUN
cord-301856-71syce4n	183	24	of	of	ADP
cord-301856-71syce4n	183	25	il-6	il-6	NOUN
cord-301856-71syce4n	183	26	and	and	CCONJ
cord-301856-71syce4n	183	27	il-1b	il-1b	PROPN
cord-301856-71syce4n	183	28	after	after	ADP
cord-301856-71syce4n	183	29	stimulation	stimulation	NOUN
cord-301856-71syce4n	183	30	with	with	ADP
cord-301856-71syce4n	183	31	lipopolysaccharide	lipopolysaccharide	NOUN
cord-301856-71syce4n	183	32	or	or	CCONJ
cord-301856-71syce4n	183	33	muramyl	muramyl	ADJ
cord-301856-71syce4n	183	34	dipeptide	dipeptide	NOUN
cord-301856-71syce4n	183	35	due	due	ADP
cord-301856-71syce4n	183	36	to	to	ADP
cord-301856-71syce4n	183	37	enhanced	enhance	VERB
cord-301856-71syce4n	183	38	activity	activity	NOUN
cord-301856-71syce4n	183	39	of	of	ADP
cord-301856-71syce4n	183	40	the	the	DET
cord-301856-71syce4n	183	41	nod2	nod2	NOUN
cord-301856-71syce4n	183	42	inflammasome	inflammasome	NOUN
cord-301856-71syce4n	183	43	pathway	pathway	NOUN
cord-301856-71syce4n	183	44	relative	relative	ADJ
cord-301856-71syce4n	183	45	to	to	ADP
cord-301856-71syce4n	183	46	controls	control	NOUN
cord-301856-71syce4n	183	47	[	[	X
cord-301856-71syce4n	183	48	72	72	NUM
cord-301856-71syce4n	183	49	]	]	PUNCT
cord-301856-71syce4n	183	50	;	;	PUNCT
cord-301856-71syce4n	183	51	this	this	PRON
cord-301856-71syce4n	183	52	has	have	AUX
cord-301856-71syce4n	183	53	suggested	suggest	VERB
cord-301856-71syce4n	183	54	an	an	DET
cord-301856-71syce4n	183	55	immune	immune	NOUN
cord-301856-71syce4n	183	56	-	-	PUNCT
cord-301856-71syce4n	183	57	related	relate	VERB
cord-301856-71syce4n	183	58	role	role	NOUN
cord-301856-71syce4n	183	59	for	for	ADP
cord-301856-71syce4n	183	60	sh2b3	sh2b3	NOUN
cord-301856-71syce4n	183	61	in	in	ADP
cord-301856-71syce4n	183	62	the	the	DET
cord-301856-71syce4n	183	63	context	context	NOUN
cord-301856-71syce4n	183	64	of	of	ADP
cord-301856-71syce4n	183	65	bacterial	bacterial	ADJ
cord-301856-71syce4n	183	66	infections	infection	NOUN
cord-301856-71syce4n	183	67	,	,	PUNCT
cord-301856-71syce4n	183	68	which	which	PRON
cord-301856-71syce4n	183	69	might	might	AUX
cord-301856-71syce4n	183	70	help	help	VERB
cord-301856-71syce4n	183	71	explain	explain	VERB
cord-301856-71syce4n	183	72	the	the	DET
cord-301856-71syce4n	183	73	positive	positive	ADJ
cord-301856-71syce4n	183	74	selection	selection	NOUN
cord-301856-71syce4n	183	75	of	of	ADP
cord-301856-71syce4n	183	76	sh2b3	sh2b3	NOUN
cord-301856-71syce4n	183	77	approximately	approximately	ADV
cord-301856-71syce4n	183	78	1500	1500	NUM
cord-301856-71syce4n	183	79	years	year	NOUN
cord-301856-71syce4n	183	80	ago	ago	ADV
cord-301856-71syce4n	183	81	[	[	X
cord-301856-71syce4n	183	82	72	72	NUM
cord-301856-71syce4n	183	83	]	]	PUNCT
cord-301856-71syce4n	183	84	.	.	PUNCT
cord-301856-71syce4n	184	1	others	other	NOUN
cord-301856-71syce4n	184	2	found	find	VERB
cord-301856-71syce4n	184	3	an	an	DET
cord-301856-71syce4n	184	4	association	association	NOUN
cord-301856-71syce4n	184	5	between	between	ADP
cord-301856-71syce4n	184	6	genetic	genetic	ADJ
cord-301856-71syce4n	184	7	variants	variant	NOUN
cord-301856-71syce4n	184	8	in	in	ADP
cord-301856-71syce4n	184	9	nod2	nod2	PROPN
cord-301856-71syce4n	184	10	,	,	PUNCT
cord-301856-71syce4n	184	11	cd14	cd14	PROPN
cord-301856-71syce4n	184	12	,	,	PUNCT
cord-301856-71syce4n	184	13	and	and	CCONJ
cord-301856-71syce4n	184	14	increased	increase	VERB
cord-301856-71syce4n	184	15	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	184	16	to	to	ADP
cord-301856-71syce4n	184	17	cd	cd	PROPN
cord-301856-71syce4n	184	18	[	[	PUNCT
cord-301856-71syce4n	184	19	73	73	NUM
cord-301856-71syce4n	184	20	]	]	PUNCT
cord-301856-71syce4n	184	21	,	,	PUNCT
cord-301856-71syce4n	184	22	in	in	ADP
cord-301856-71syce4n	184	23	line	line	NOUN
cord-301856-71syce4n	184	24	with	with	ADP
cord-301856-71syce4n	184	25	previous	previous	ADJ
cord-301856-71syce4n	184	26	results	result	NOUN
cord-301856-71syce4n	184	27	showing	show	VERB
cord-301856-71syce4n	184	28	that	that	SCONJ
cord-301856-71syce4n	184	29	mutations	mutation	NOUN
cord-301856-71syce4n	184	30	in	in	ADP
cord-301856-71syce4n	184	31	nod2	nod2	PROPN
cord-301856-71syce4n	184	32	and	and	CCONJ
cord-301856-71syce4n	184	33	tlr4	tlr4	PROPN
cord-301856-71syce4n	184	34	/	/	SYM
cord-301856-71syce4n	184	35	cd14	cd14	PROPN
cord-301856-71syce4n	184	36	are	be	AUX
cord-301856-71syce4n	184	37	related	relate	VERB
cord-301856-71syce4n	184	38	to	to	ADP
cord-301856-71syce4n	184	39	an	an	DET
cord-301856-71syce4n	184	40	increased	increase	VERB
cord-301856-71syce4n	184	41	risk	risk	NOUN
cord-301856-71syce4n	184	42	of	of	ADP
cord-301856-71syce4n	184	43	developing	develop	VERB
cord-301856-71syce4n	184	44	ibd	ibd	NOUN
cord-301856-71syce4n	185	1	[	[	PUNCT
cord-301856-71syce4n	185	2	74	74	NUM
cord-301856-71syce4n	185	3	]	]	PUNCT
cord-301856-71syce4n	185	4	.	.	PUNCT
cord-301856-71syce4n	186	1	from	from	ADP
cord-301856-71syce4n	186	2	another	another	DET
cord-301856-71syce4n	186	3	angle	angle	NOUN
cord-301856-71syce4n	186	4	,	,	PUNCT
cord-301856-71syce4n	186	5	changes	change	NOUN
cord-301856-71syce4n	186	6	in	in	ADP
cord-301856-71syce4n	186	7	hygiene	hygiene	ADJ
cord-301856-71syce4n	186	8	patterns	pattern	NOUN
cord-301856-71syce4n	186	9	seen	see	VERB
cord-301856-71syce4n	186	10	in	in	ADP
cord-301856-71syce4n	186	11	the	the	DET
cord-301856-71syce4n	186	12	past	past	ADJ
cord-301856-71syce4n	186	13	two	two	NUM
cord-301856-71syce4n	186	14	centuries	century	NOUN
cord-301856-71syce4n	186	15	brought	bring	VERB
cord-301856-71syce4n	186	16	vast	vast	ADJ
cord-301856-71syce4n	186	17	improvements	improvement	NOUN
cord-301856-71syce4n	186	18	in	in	ADP
cord-301856-71syce4n	186	19	sanitation	sanitation	NOUN
cord-301856-71syce4n	186	20	,	,	PUNCT
cord-301856-71syce4n	186	21	drinking	drinking	NOUN
cord-301856-71syce4n	186	22	water	water	NOUN
cord-301856-71syce4n	186	23	,	,	PUNCT
cord-301856-71syce4n	186	24	and	and	CCONJ
cord-301856-71syce4n	186	25	garbage	garbage	NOUN
cord-301856-71syce4n	186	26	collection	collection	NOUN
cord-301856-71syce4n	186	27	,	,	PUNCT
cord-301856-71syce4n	186	28	which	which	PRON
cord-301856-71syce4n	186	29	greatly	greatly	ADV
cord-301856-71syce4n	186	30	reduced	reduce	VERB
cord-301856-71syce4n	186	31	the	the	DET
cord-301856-71syce4n	186	32	exposure	exposure	NOUN
cord-301856-71syce4n	186	33	to	to	ADP
cord-301856-71syce4n	186	34	many	many	ADJ
cord-301856-71syce4n	186	35	infectious	infectious	ADJ
cord-301856-71syce4n	186	36	diseases	disease	NOUN
cord-301856-71syce4n	186	37	.	.	PUNCT
cord-301856-71syce4n	187	1	however	however	ADV
cord-301856-71syce4n	187	2	,	,	PUNCT
cord-301856-71syce4n	187	3	these	these	DET
cord-301856-71syce4n	187	4	conditions	condition	NOUN
cord-301856-71syce4n	187	5	may	may	AUX
cord-301856-71syce4n	187	6	have	have	AUX
cord-301856-71syce4n	187	7	reduced	reduce	VERB
cord-301856-71syce4n	187	8	the	the	DET
cord-301856-71syce4n	187	9	exposure	exposure	NOUN
cord-301856-71syce4n	187	10	to	to	ADP
cord-301856-71syce4n	187	11	viral	viral	ADJ
cord-301856-71syce4n	187	12	and	and	CCONJ
cord-301856-71syce4n	187	13	microbial	microbial	ADJ
cord-301856-71syce4n	187	14	agents	agent	NOUN
cord-301856-71syce4n	187	15	that	that	PRON
cord-301856-71syce4n	187	16	help	help	VERB
cord-301856-71syce4n	187	17	the	the	DET
cord-301856-71syce4n	187	18	immune	immune	ADJ
cord-301856-71syce4n	187	19	system	system	NOUN
cord-301856-71syce4n	187	20	to	to	PART
cord-301856-71syce4n	187	21	develop	develop	VERB
cord-301856-71syce4n	187	22	tolerance	tolerance	NOUN
cord-301856-71syce4n	187	23	during	during	ADP
cord-301856-71syce4n	187	24	childhood	childhood	NOUN
cord-301856-71syce4n	187	25	.	.	PUNCT
cord-301856-71syce4n	188	1	the	the	DET
cord-301856-71syce4n	188	2	hygiene	hygiene	ADJ
cord-301856-71syce4n	188	3	hypothesis	hypothesis	NOUN
cord-301856-71syce4n	188	4	proposes	propose	VERB
cord-301856-71syce4n	188	5	that	that	SCONJ
cord-301856-71syce4n	188	6	the	the	DET
cord-301856-71syce4n	188	7	lack	lack	NOUN
cord-301856-71syce4n	188	8	of	of	ADP
cord-301856-71syce4n	188	9	exposure	exposure	NOUN
cord-301856-71syce4n	188	10	to	to	ADP
cord-301856-71syce4n	188	11	microbial	microbial	ADJ
cord-301856-71syce4n	188	12	agents	agent	NOUN
cord-301856-71syce4n	188	13	in	in	ADP
cord-301856-71syce4n	188	14	the	the	DET
cord-301856-71syce4n	188	15	early	early	ADJ
cord-301856-71syce4n	188	16	stages	stage	NOUN
cord-301856-71syce4n	188	17	of	of	ADP
cord-301856-71syce4n	188	18	life	life	NOUN
cord-301856-71syce4n	188	19	is	be	AUX
cord-301856-71syce4n	188	20	related	relate	VERB
cord-301856-71syce4n	188	21	to	to	ADP
cord-301856-71syce4n	188	22	a	a	DET
cord-301856-71syce4n	188	23	higher	high	ADJ
cord-301856-71syce4n	188	24	risk	risk	NOUN
cord-301856-71syce4n	188	25	of	of	ADP
cord-301856-71syce4n	188	26	developing	develop	VERB
cord-301856-71syce4n	188	27	hypersensitivity	hypersensitivity	NOUN
cord-301856-71syce4n	188	28	reactions	reaction	NOUN
cord-301856-71syce4n	188	29	,	,	PUNCT
cord-301856-71syce4n	188	30	based	base	VERB
cord-301856-71syce4n	188	31	on	on	ADP
cord-301856-71syce4n	188	32	the	the	DET
cord-301856-71syce4n	188	33	fact	fact	NOUN
cord-301856-71syce4n	188	34	that	that	SCONJ
cord-301856-71syce4n	188	35	children	child	NOUN
cord-301856-71syce4n	188	36	that	that	PRON
cord-301856-71syce4n	188	37	are	be	AUX
cord-301856-71syce4n	188	38	exposed	expose	VERB
cord-301856-71syce4n	188	39	to	to	ADP
cord-301856-71syce4n	188	40	higher	high	ADJ
cord-301856-71syce4n	188	41	amounts	amount	NOUN
cord-301856-71syce4n	188	42	of	of	ADP
cord-301856-71syce4n	188	43	microbial	microbial	ADJ
cord-301856-71syce4n	188	44	stimuli	stimulus	NOUN
cord-301856-71syce4n	188	45	(	(	PUNCT
cord-301856-71syce4n	188	46	e.g.	e.g.	ADV
cord-301856-71syce4n	188	47	,	,	PUNCT
cord-301856-71syce4n	188	48	by	by	ADP
cord-301856-71syce4n	188	49	growing	grow	VERB
cord-301856-71syce4n	188	50	on	on	ADP
cord-301856-71syce4n	188	51	farms	farm	NOUN
cord-301856-71syce4n	188	52	)	)	PUNCT
cord-301856-71syce4n	188	53	are	be	AUX
cord-301856-71syce4n	188	54	less	less	ADV
cord-301856-71syce4n	188	55	prone	prone	ADJ
cord-301856-71syce4n	188	56	to	to	PART
cord-301856-71syce4n	188	57	develop	develop	VERB
cord-301856-71syce4n	188	58	allergies	allergy	NOUN
cord-301856-71syce4n	188	59	and	and	CCONJ
cord-301856-71syce4n	188	60	asthma	asthma	NOUN
cord-301856-71syce4n	188	61	[	[	NOUN
cord-301856-71syce4n	188	62	75	75	NUM
cord-301856-71syce4n	188	63	,	,	PUNCT
cord-301856-71syce4n	188	64	76	76	NUM
cord-301856-71syce4n	188	65	]	]	PUNCT
cord-301856-71syce4n	188	66	.	.	PUNCT
cord-301856-71syce4n	189	1	moreover	moreover	ADV
cord-301856-71syce4n	189	2	,	,	PUNCT
cord-301856-71syce4n	189	3	reduced	reduce	VERB
cord-301856-71syce4n	189	4	exposure	exposure	NOUN
cord-301856-71syce4n	189	5	to	to	ADP
cord-301856-71syce4n	189	6	infectious	infectious	ADJ
cord-301856-71syce4n	189	7	agents	agent	NOUN
cord-301856-71syce4n	189	8	can	can	AUX
cord-301856-71syce4n	189	9	have	have	VERB
cord-301856-71syce4n	189	10	a	a	DET
cord-301856-71syce4n	189	11	much	much	ADV
cord-301856-71syce4n	189	12	wider	wide	ADJ
cord-301856-71syce4n	189	13	effect	effect	NOUN
cord-301856-71syce4n	189	14	than	than	SCONJ
cord-301856-71syce4n	189	15	initially	initially	ADV
cord-301856-71syce4n	189	16	believed	believe	VERB
cord-301856-71syce4n	189	17	.	.	PUNCT
cord-301856-71syce4n	190	1	lack	lack	NOUN
cord-301856-71syce4n	190	2	of	of	ADP
cord-301856-71syce4n	190	3	exposure	exposure	NOUN
cord-301856-71syce4n	190	4	to	to	ADP
cord-301856-71syce4n	190	5	microbes	microbe	NOUN
cord-301856-71syce4n	190	6	in	in	ADP
cord-301856-71syce4n	190	7	childhood	childhood	NOUN
cord-301856-71syce4n	190	8	can	can	AUX
cord-301856-71syce4n	190	9	cause	cause	VERB
cord-301856-71syce4n	190	10	aberrant	aberrant	ADJ
cord-301856-71syce4n	190	11	responses	response	NOUN
cord-301856-71syce4n	190	12	to	to	ADP
cord-301856-71syce4n	190	13	infection	infection	NOUN
cord-301856-71syce4n	190	14	and	and	CCONJ
cord-301856-71syce4n	190	15	potentiate	potentiate	VERB
cord-301856-71syce4n	190	16	the	the	DET
cord-301856-71syce4n	190	17	effects	effect	NOUN
cord-301856-71syce4n	190	18	of	of	ADP
cord-301856-71syce4n	190	19	etv6	etv6	PROPN
cord-301856-71syce4n	190	20	-	-	PUNCT
cord-301856-71syce4n	190	21	runx1	runx1	PROPN
cord-301856-71syce4n	190	22	mutations	mutation	NOUN
cord-301856-71syce4n	190	23	in	in	ADP
cord-301856-71syce4n	190	24	the	the	DET
cord-301856-71syce4n	190	25	pathogenesis	pathogenesis	NOUN
cord-301856-71syce4n	190	26	of	of	ADP
cord-301856-71syce4n	190	27	acute	acute	ADJ
cord-301856-71syce4n	190	28	lymphoblastic	lymphoblastic	NOUN
cord-301856-71syce4n	190	29	leukemia	leukemia	NOUN
cord-301856-71syce4n	190	30	[	[	PUNCT
cord-301856-71syce4n	190	31	77	77	NUM
cord-301856-71syce4n	190	32	]	]	PUNCT
cord-301856-71syce4n	190	33	.	.	PUNCT
cord-301856-71syce4n	191	1	by	by	ADP
cord-301856-71syce4n	191	2	contrast	contrast	NOUN
cord-301856-71syce4n	191	3	,	,	PUNCT
cord-301856-71syce4n	191	4	a	a	DET
cord-301856-71syce4n	191	5	meta	meta	NOUN
cord-301856-71syce4n	191	6	-	-	PUNCT
cord-301856-71syce4n	191	7	analysis	analysis	NOUN
cord-301856-71syce4n	191	8	of	of	ADP
cord-301856-71syce4n	191	9	six	six	NUM
cord-301856-71syce4n	191	10	observational	observational	ADJ
cord-301856-71syce4n	191	11	studies	study	NOUN
cord-301856-71syce4n	191	12	,	,	PUNCT
cord-301856-71syce4n	191	13	including	include	VERB
cord-301856-71syce4n	191	14	1902	1902	NUM
cord-301856-71syce4n	191	15	participants	participant	NOUN
cord-301856-71syce4n	191	16	,	,	PUNCT
cord-301856-71syce4n	191	17	showed	show	VERB
cord-301856-71syce4n	191	18	a	a	DET
cord-301856-71syce4n	191	19	correlation	correlation	NOUN
cord-301856-71syce4n	191	20	between	between	ADP
cord-301856-71syce4n	191	21	low	low	ADJ
cord-301856-71syce4n	191	22	helicobacter	helicobacter	NOUN
cord-301856-71syce4n	191	23	pylori	pylori	NOUN
cord-301856-71syce4n	191	24	infection	infection	NOUN
cord-301856-71syce4n	191	25	and	and	CCONJ
cord-301856-71syce4n	191	26	ms	ms	PROPN
cord-301856-71syce4n	191	27	,	,	PUNCT
cord-301856-71syce4n	191	28	suggesting	suggest	VERB
cord-301856-71syce4n	191	29	that	that	SCONJ
cord-301856-71syce4n	191	30	low	low	ADJ
cord-301856-71syce4n	191	31	h.	h.	NOUN
cord-301856-71syce4n	191	32	pylori	pylori	NOUN
cord-301856-71syce4n	191	33	prevalence	prevalence	NOUN
cord-301856-71syce4n	191	34	might	might	AUX
cord-301856-71syce4n	191	35	be	be	AUX
cord-301856-71syce4n	191	36	a	a	DET
cord-301856-71syce4n	191	37	putative	putative	ADJ
cord-301856-71syce4n	191	38	protective	protective	ADJ
cord-301856-71syce4n	191	39	factor	factor	NOUN
cord-301856-71syce4n	191	40	in	in	ADP
cord-301856-71syce4n	191	41	ms	ms	PROPN
cord-301856-71syce4n	191	42	,	,	PUNCT
cord-301856-71syce4n	191	43	although	although	SCONJ
cord-301856-71syce4n	191	44	this	this	PRON
cord-301856-71syce4n	191	45	remains	remain	VERB
cord-301856-71syce4n	191	46	to	to	PART
cord-301856-71syce4n	191	47	be	be	AUX
cord-301856-71syce4n	191	48	experimentally	experimentally	ADV
cord-301856-71syce4n	191	49	validated	validate	VERB
cord-301856-71syce4n	191	50	[	[	X
cord-301856-71syce4n	191	51	78	78	NUM
cord-301856-71syce4n	191	52	]	]	PUNCT
cord-301856-71syce4n	191	53	.	.	PUNCT
cord-301856-71syce4n	192	1	one	one	NUM
cord-301856-71syce4n	192	2	study	study	NOUN
cord-301856-71syce4n	192	3	also	also	ADV
cord-301856-71syce4n	192	4	reported	report	VERB
cord-301856-71syce4n	192	5	that	that	SCONJ
cord-301856-71syce4n	192	6	antibodies	antibody	NOUN
cord-301856-71syce4n	192	7	against	against	ADP
cord-301856-71syce4n	192	8	toxoplasma	toxoplasma	ADJ
cord-301856-71syce4n	192	9	gondii	gondii	NOUN
cord-301856-71syce4n	192	10	were	be	AUX
cord-301856-71syce4n	192	11	detected	detect	VERB
cord-301856-71syce4n	192	12	less	less	ADV
cord-301856-71syce4n	192	13	often	often	ADV
cord-301856-71syce4n	192	14	in	in	ADP
cord-301856-71syce4n	192	15	patients	patient	NOUN
cord-301856-71syce4n	192	16	with	with	ADP
cord-301856-71syce4n	192	17	ms	ms	NOUN
cord-301856-71syce4n	192	18	compared	compare	VERB
cord-301856-71syce4n	192	19	with	with	ADP
cord-301856-71syce4n	192	20	healthy	healthy	ADJ
cord-301856-71syce4n	192	21	controls	control	NOUN
cord-301856-71syce4n	192	22	[	[	X
cord-301856-71syce4n	192	23	79	79	NUM
cord-301856-71syce4n	192	24	]	]	PUNCT
cord-301856-71syce4n	192	25	.	.	PUNCT
cord-301856-71syce4n	193	1	however	however	ADV
cord-301856-71syce4n	193	2	,	,	PUNCT
cord-301856-71syce4n	193	3	these	these	DET
cord-301856-71syce4n	193	4	findings	finding	NOUN
cord-301856-71syce4n	193	5	warrant	warrant	VERB
cord-301856-71syce4n	193	6	further	far	ADV
cord-301856-71syce4n	193	7	and	and	CCONJ
cord-301856-71syce4n	193	8	robust	robust	ADJ
cord-301856-71syce4n	193	9	investigation	investigation	NOUN
cord-301856-71syce4n	193	10	.	.	PUNCT
cord-301856-71syce4n	194	1	overall	overall	ADV
cord-301856-71syce4n	194	2	,	,	PUNCT
cord-301856-71syce4n	194	3	it	it	PRON
cord-301856-71syce4n	194	4	is	be	AUX
cord-301856-71syce4n	194	5	clear	clear	ADJ
cord-301856-71syce4n	194	6	that	that	SCONJ
cord-301856-71syce4n	194	7	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	194	8	processes	process	NOUN
cord-301856-71syce4n	194	9	can	can	AUX
cord-301856-71syce4n	194	10	drive	drive	VERB
cord-301856-71syce4n	194	11	the	the	DET
cord-301856-71syce4n	194	12	fixation	fixation	NOUN
cord-301856-71syce4n	194	13	of	of	ADP
cord-301856-71syce4n	194	14	genetic	genetic	ADJ
cord-301856-71syce4n	194	15	variations	variation	NOUN
cord-301856-71syce4n	194	16	that	that	PRON
cord-301856-71syce4n	194	17	increase	increase	VERB
cord-301856-71syce4n	194	18	(	(	PUNCT
cord-301856-71syce4n	194	19	or	or	CCONJ
cord-301856-71syce4n	194	20	decrease	decrease	VERB
cord-301856-71syce4n	194	21	)	)	PUNCT
cord-301856-71syce4n	194	22	our	our	PRON
cord-301856-71syce4n	194	23	defense	defense	NOUN
cord-301856-71syce4n	194	24	against	against	ADP
cord-301856-71syce4n	194	25	infections	infection	NOUN
cord-301856-71syce4n	194	26	upon	upon	SCONJ
cord-301856-71syce4n	194	27	sensing	sense	VERB
cord-301856-71syce4n	194	28	microbial	microbial	ADJ
cord-301856-71syce4n	194	29	ligands	ligand	NOUN
cord-301856-71syce4n	194	30	,	,	PUNCT
cord-301856-71syce4n	194	31	but	but	CCONJ
cord-301856-71syce4n	194	32	can	can	AUX
cord-301856-71syce4n	194	33	also	also	ADV
cord-301856-71syce4n	194	34	lead	lead	VERB
cord-301856-71syce4n	194	35	to	to	ADP
cord-301856-71syce4n	194	36	a	a	DET
cord-301856-71syce4n	194	37	greater	great	ADJ
cord-301856-71syce4n	194	38	risk	risk	NOUN
cord-301856-71syce4n	194	39	of	of	ADP
cord-301856-71syce4n	194	40	developing	develop	VERB
cord-301856-71syce4n	194	41	certain	certain	ADJ
cord-301856-71syce4n	194	42	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	194	43	diseases	disease	NOUN
cord-301856-71syce4n	194	44	in	in	ADP
cord-301856-71syce4n	194	45	which	which	PRON
cord-301856-71syce4n	194	46	endogenous	endogenous	ADJ
cord-301856-71syce4n	194	47	ligands	ligand	NOUN
cord-301856-71syce4n	194	48	can	can	AUX
cord-301856-71syce4n	194	49	cause	cause	VERB
cord-301856-71syce4n	194	50	tissue	tissue	NOUN
cord-301856-71syce4n	194	51	damage	damage	NOUN
cord-301856-71syce4n	194	52	and	and	CCONJ
cord-301856-71syce4n	194	53	inflammation	inflammation	NOUN
cord-301856-71syce4n	194	54	.	.	PUNCT
cord-301856-71syce4n	195	1	a	a	DET
cord-301856-71syce4n	195	2	growing	grow	VERB
cord-301856-71syce4n	195	3	number	number	NOUN
cord-301856-71syce4n	195	4	of	of	ADP
cord-301856-71syce4n	195	5	reports	report	NOUN
cord-301856-71syce4n	195	6	suggest	suggest	VERB
cord-301856-71syce4n	195	7	that	that	SCONJ
cord-301856-71syce4n	195	8	inheritance	inheritance	NOUN
cord-301856-71syce4n	195	9	is	be	AUX
cord-301856-71syce4n	195	10	not	not	PART
cord-301856-71syce4n	195	11	always	always	ADV
cord-301856-71syce4n	195	12	governed	govern	VERB
cord-301856-71syce4n	195	13	by	by	ADP
cord-301856-71syce4n	195	14	classical	classical	ADJ
cord-301856-71syce4n	195	15	darwinian	darwinian	ADJ
cord-301856-71syce4n	195	16	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	195	17	processes	process	NOUN
cord-301856-71syce4n	195	18	.	.	PUNCT
cord-301856-71syce4n	196	1	exposure	exposure	NOUN
cord-301856-71syce4n	196	2	to	to	ADP
cord-301856-71syce4n	196	3	certain	certain	ADJ
cord-301856-71syce4n	196	4	environmental	environmental	ADJ
cord-301856-71syce4n	196	5	stimuli	stimulus	NOUN
cord-301856-71syce4n	196	6	can	can	AUX
cord-301856-71syce4n	196	7	cause	cause	VERB
cord-301856-71syce4n	196	8	effects	effect	NOUN
cord-301856-71syce4n	196	9	in	in	ADP
cord-301856-71syce4n	196	10	the	the	DET
cord-301856-71syce4n	196	11	progeny	progeny	NOUN
cord-301856-71syce4n	196	12	of	of	ADP
cord-301856-71syce4n	196	13	an	an	DET
cord-301856-71syce4n	196	14	exposed	expose	VERB
cord-301856-71syce4n	196	15	individual	individual	NOUN
cord-301856-71syce4n	196	16	,	,	PUNCT
cord-301856-71syce4n	196	17	even	even	ADV
cord-301856-71syce4n	196	18	though	though	SCONJ
cord-301856-71syce4n	196	19	the	the	DET
cord-301856-71syce4n	196	20	stimuli	stimulus	NOUN
cord-301856-71syce4n	196	21	are	be	AUX
cord-301856-71syce4n	196	22	no	no	ADV
cord-301856-71syce4n	196	23	longer	long	ADV
cord-301856-71syce4n	196	24	present	present	ADJ
cord-301856-71syce4n	196	25	.	.	PUNCT
cord-301856-71syce4n	197	1	this	this	DET
cord-301856-71syce4n	197	2	type	type	NOUN
cord-301856-71syce4n	197	3	of	of	ADP
cord-301856-71syce4n	197	4	transgenerational	transgenerational	ADJ
cord-301856-71syce4n	197	5	inheritance	inheritance	NOUN
cord-301856-71syce4n	197	6	might	might	AUX
cord-301856-71syce4n	197	7	be	be	AUX
cord-301856-71syce4n	197	8	explained	explain	VERB
cord-301856-71syce4n	197	9	through	through	ADP
cord-301856-71syce4n	197	10	the	the	DET
cord-301856-71syce4n	197	11	effects	effect	NOUN
cord-301856-71syce4n	197	12	of	of	ADP
cord-301856-71syce4n	197	13	epigenetic	epigenetic	ADJ
cord-301856-71syce4n	197	14	processes	process	NOUN
cord-301856-71syce4n	197	15	,	,	PUNCT
cord-301856-71syce4n	197	16	which	which	PRON
cord-301856-71syce4n	197	17	are	be	AUX
cord-301856-71syce4n	197	18	hypothesized	hypothesize	VERB
cord-301856-71syce4n	197	19	to	to	PART
cord-301856-71syce4n	197	20	be	be	AUX
cord-301856-71syce4n	197	21	transmitted	transmit	VERB
cord-301856-71syce4n	197	22	through	through	ADP
cord-301856-71syce4n	197	23	the	the	DET
cord-301856-71syce4n	197	24	germline	germline	NOUN
cord-301856-71syce4n	197	25	and	and	CCONJ
cord-301856-71syce4n	197	26	passed	pass	VERB
cord-301856-71syce4n	197	27	on	on	ADP
cord-301856-71syce4n	197	28	to	to	ADP
cord-301856-71syce4n	197	29	the	the	DET
cord-301856-71syce4n	197	30	offspring	offspring	NOUN
cord-301856-71syce4n	197	31	[	[	X
cord-301856-71syce4n	197	32	80	80	NUM
cord-301856-71syce4n	197	33	]	]	PUNCT
cord-301856-71syce4n	197	34	.	.	PUNCT
cord-301856-71syce4n	198	1	for	for	ADP
cord-301856-71syce4n	198	2	example	example	NOUN
cord-301856-71syce4n	198	3	,	,	PUNCT
cord-301856-71syce4n	198	4	the	the	DET
cord-301856-71syce4n	198	5	worm	worm	PROPN
cord-301856-71syce4n	198	6	caenorhabditis	caenorhabditis	PROPN
cord-301856-71syce4n	198	7	elegans	elegan	NOUN
cord-301856-71syce4n	198	8	can	can	AUX
cord-301856-71syce4n	198	9	transmit	transmit	VERB
cord-301856-71syce4n	198	10	improved	improved	ADJ
cord-301856-71syce4n	198	11	resistance	resistance	NOUN
cord-301856-71syce4n	198	12	to	to	ADP
cord-301856-71syce4n	198	13	infections	infection	NOUN
cord-301856-71syce4n	198	14	to	to	ADP
cord-301856-71syce4n	198	15	pathogenic	pathogenic	ADJ
cord-301856-71syce4n	198	16	bacteria	bacteria	NOUN
cord-301856-71syce4n	198	17	to	to	ADP
cord-301856-71syce4n	198	18	their	their	PRON
cord-301856-71syce4n	198	19	offspring	offspring	NOUN
cord-301856-71syce4n	198	20	through	through	ADP
cord-301856-71syce4n	198	21	alterations	alteration	NOUN
cord-301856-71syce4n	198	22	of	of	ADP
cord-301856-71syce4n	198	23	the	the	DET
cord-301856-71syce4n	198	24	histone	histone	NOUN
cord-301856-71syce4n	198	25	landscape	landscape	NOUN
cord-301856-71syce4n	198	26	[	[	X
cord-301856-71syce4n	198	27	81	81	NUM
cord-301856-71syce4n	198	28	]	]	PUNCT
cord-301856-71syce4n	198	29	.	.	PUNCT
cord-301856-71syce4n	199	1	indian	indian	ADJ
cord-301856-71syce4n	199	2	meal	meal	NOUN
cord-301856-71syce4n	199	3	moths	moth	NOUN
cord-301856-71syce4n	199	4	exposed	expose	VERB
cord-301856-71syce4n	199	5	to	to	ADP
cord-301856-71syce4n	199	6	low	low	ADJ
cord-301856-71syce4n	199	7	doses	dose	NOUN
cord-301856-71syce4n	199	8	of	of	ADP
cord-301856-71syce4n	199	9	virus	virus	NOUN
cord-301856-71syce4n	199	10	are	be	AUX
cord-301856-71syce4n	199	11	subsequently	subsequently	ADV
cord-301856-71syce4n	199	12	less	less	ADV
cord-301856-71syce4n	199	13	susceptible	susceptible	ADJ
cord-301856-71syce4n	199	14	to	to	ADP
cord-301856-71syce4n	199	15	viral	viral	ADJ
cord-301856-71syce4n	199	16	challenge	challenge	NOUN
cord-301856-71syce4n	199	17	,	,	PUNCT
cord-301856-71syce4n	199	18	a	a	DET
cord-301856-71syce4n	199	19	protection	protection	NOUN
cord-301856-71syce4n	199	20	offered	offer	VERB
cord-301856-71syce4n	199	21	to	to	ADP
cord-301856-71syce4n	199	22	their	their	PRON
cord-301856-71syce4n	199	23	offspring	offspring	NOUN
cord-301856-71syce4n	199	24	as	as	ADV
cord-301856-71syce4n	199	25	well	well	ADV
cord-301856-71syce4n	199	26	[	[	X
cord-301856-71syce4n	199	27	82	82	NUM
cord-301856-71syce4n	199	28	]	]	PUNCT
cord-301856-71syce4n	199	29	.	.	PUNCT
cord-301856-71syce4n	200	1	transgenerational	transgenerational	ADJ
cord-301856-71syce4n	200	2	inheritance	inheritance	NOUN
cord-301856-71syce4n	200	3	of	of	ADP
cord-301856-71syce4n	200	4	diverse	diverse	ADJ
cord-301856-71syce4n	200	5	traits	trait	NOUN
cord-301856-71syce4n	200	6	has	have	AUX
cord-301856-71syce4n	200	7	also	also	ADV
cord-301856-71syce4n	200	8	been	be	AUX
cord-301856-71syce4n	200	9	observed	observe	VERB
cord-301856-71syce4n	200	10	in	in	ADP
cord-301856-71syce4n	200	11	mice	mouse	NOUN
cord-301856-71syce4n	200	12	,	,	PUNCT
cord-301856-71syce4n	200	13	in	in	ADP
cord-301856-71syce4n	200	14	which	which	PRON
cord-301856-71syce4n	200	15	the	the	DET
cord-301856-71syce4n	200	16	variation	variation	NOUN
cord-301856-71syce4n	200	17	of	of	ADP
cord-301856-71syce4n	200	18	the	the	DET
cord-301856-71syce4n	200	19	color	color	NOUN
cord-301856-71syce4n	200	20	of	of	ADP
cord-301856-71syce4n	200	21	the	the	DET
cord-301856-71syce4n	200	22	coat	coat	NOUN
cord-301856-71syce4n	200	23	is	be	AUX
cord-301856-71syce4n	200	24	passed	pass	VERB
cord-301856-71syce4n	200	25	on	on	ADP
cord-301856-71syce4n	200	26	the	the	DET
cord-301856-71syce4n	200	27	next	next	ADJ
cord-301856-71syce4n	200	28	generation	generation	NOUN
cord-301856-71syce4n	200	29	[	[	PUNCT
cord-301856-71syce4n	200	30	83	83	NUM
cord-301856-71syce4n	200	31	,	,	PUNCT
cord-301856-71syce4n	200	32	84	84	NUM
cord-301856-71syce4n	200	33	]	]	PUNCT
cord-301856-71syce4n	200	34	.	.	PUNCT
cord-301856-71syce4n	201	1	offspring	offspring	NOUN
cord-301856-71syce4n	201	2	of	of	ADP
cord-301856-71syce4n	201	3	male	male	ADJ
cord-301856-71syce4n	201	4	rats	rat	NOUN
cord-301856-71syce4n	201	5	subjected	subject	VERB
cord-301856-71syce4n	201	6	to	to	ADP
cord-301856-71syce4n	201	7	a	a	DET
cord-301856-71syce4n	201	8	high	high	ADJ
cord-301856-71syce4n	201	9	-	-	PUNCT
cord-301856-71syce4n	201	10	fat	fat	NOUN
cord-301856-71syce4n	201	11	diet	diet	NOUN
cord-301856-71syce4n	201	12	present	present	ADJ
cord-301856-71syce4n	201	13	glucose	glucose	NOUN
cord-301856-71syce4n	201	14	intolerance	intolerance	NOUN
cord-301856-71syce4n	201	15	and	and	CCONJ
cord-301856-71syce4n	201	16	reduced	reduce	VERB
cord-301856-71syce4n	201	17	insulin	insulin	NOUN
cord-301856-71syce4n	201	18	secretion	secretion	NOUN
cord-301856-71syce4n	201	19	,	,	PUNCT
cord-301856-71syce4n	201	20	linked	link	VERB
cord-301856-71syce4n	201	21	to	to	ADP
cord-301856-71syce4n	201	22	reduced	reduce	VERB
cord-301856-71syce4n	201	23	methylation	methylation	NOUN
cord-301856-71syce4n	201	24	at	at	ADP
cord-301856-71syce4n	201	25	the	the	DET
cord-301856-71syce4n	201	26	il13ra2	il13ra2	ADJ
cord-301856-71syce4n	201	27	gene	gene	NOUN
cord-301856-71syce4n	201	28	relative	relative	ADJ
cord-301856-71syce4n	201	29	to	to	ADP
cord-301856-71syce4n	201	30	controls	control	NOUN
cord-301856-71syce4n	201	31	[	[	SYM
cord-301856-71syce4n	201	32	85	85	NUM
cord-301856-71syce4n	201	33	]	]	PUNCT
cord-301856-71syce4n	201	34	;	;	PUNCT
cord-301856-71syce4n	201	35	and	and	CCONJ
cord-301856-71syce4n	201	36	mice	mouse	NOUN
cord-301856-71syce4n	201	37	fed	feed	VERB
cord-301856-71syce4n	201	38	scorpions	scorpion	NOUN
cord-301856-71syce4n	201	39	are	be	AUX
cord-301856-71syce4n	201	40	more	more	ADV
cord-301856-71syce4n	201	41	resistant	resistant	ADJ
cord-301856-71syce4n	201	42	to	to	ADP
cord-301856-71syce4n	201	43	a	a	DET
cord-301856-71syce4n	201	44	challenge	challenge	NOUN
cord-301856-71syce4n	201	45	with	with	ADP
cord-301856-71syce4n	201	46	scorpion	scorpion	NOUN
cord-301856-71syce4n	201	47	venom	venom	NOUN
cord-301856-71syce4n	201	48	than	than	ADP
cord-301856-71syce4n	201	49	mice	mouse	NOUN
cord-301856-71syce4n	201	50	on	on	ADP
cord-301856-71syce4n	201	51	a	a	DET
cord-301856-71syce4n	201	52	normal	normal	ADJ
cord-301856-71syce4n	201	53	diet	diet	NOUN
cord-301856-71syce4n	202	1	[	[	X
cord-301856-71syce4n	202	2	86	86	NUM
cord-301856-71syce4n	202	3	]	]	PUNCT
cord-301856-71syce4n	202	4	.	.	PUNCT
cord-301856-71syce4n	203	1	since	since	SCONJ
cord-301856-71syce4n	203	2	infections	infection	NOUN
cord-301856-71syce4n	203	3	are	be	AUX
cord-301856-71syce4n	203	4	one	one	NUM
cord-301856-71syce4n	203	5	of	of	ADP
cord-301856-71syce4n	203	6	the	the	DET
cord-301856-71syce4n	203	7	strongest	strong	ADJ
cord-301856-71syce4n	203	8	factors	factor	NOUN
cord-301856-71syce4n	203	9	impacting	impact	VERB
cord-301856-71syce4n	203	10	survival	survival	NOUN
cord-301856-71syce4n	203	11	,	,	PUNCT
cord-301856-71syce4n	203	12	it	it	PRON
cord-301856-71syce4n	203	13	is	be	AUX
cord-301856-71syce4n	203	14	conceivable	conceivable	ADJ
cord-301856-71syce4n	203	15	that	that	SCONJ
cord-301856-71syce4n	203	16	transgenerational	transgenerational	ADJ
cord-301856-71syce4n	203	17	transmission	transmission	NOUN
cord-301856-71syce4n	203	18	of	of	ADP
cord-301856-71syce4n	203	19	traits	trait	NOUN
cord-301856-71syce4n	203	20	in	in	ADP
cord-301856-71syce4n	203	21	mammals	mammal	NOUN
cord-301856-71syce4n	203	22	,	,	PUNCT
cord-301856-71syce4n	203	23	including	include	VERB
cord-301856-71syce4n	203	24	humans	human	NOUN
cord-301856-71syce4n	203	25	,	,	PUNCT
cord-301856-71syce4n	203	26	evolved	evolve	VERB
cord-301856-71syce4n	203	27	to	to	PART
cord-301856-71syce4n	203	28	improve	improve	VERB
cord-301856-71syce4n	203	29	host	host	NOUN
cord-301856-71syce4n	203	30	defense	defense	NOUN
cord-301856-71syce4n	203	31	.	.	PUNCT
cord-301856-71syce4n	204	1	the	the	DET
cord-301856-71syce4n	204	2	number	number	NOUN
cord-301856-71syce4n	204	3	of	of	ADP
cord-301856-71syce4n	204	4	studies	study	NOUN
cord-301856-71syce4n	204	5	of	of	ADP
cord-301856-71syce4n	204	6	the	the	DET
cord-301856-71syce4n	204	7	potential	potential	ADJ
cord-301856-71syce4n	204	8	role	role	NOUN
cord-301856-71syce4n	204	9	of	of	ADP
cord-301856-71syce4n	204	10	epigenetic	epigenetic	ADJ
cord-301856-71syce4n	204	11	inheritance	inheritance	NOUN
cord-301856-71syce4n	204	12	in	in	ADP
cord-301856-71syce4n	204	13	shaping	shape	VERB
cord-301856-71syce4n	204	14	the	the	DET
cord-301856-71syce4n	204	15	human	human	ADJ
cord-301856-71syce4n	204	16	immune	immune	ADJ
cord-301856-71syce4n	204	17	system	system	NOUN
cord-301856-71syce4n	204	18	is	be	AUX
cord-301856-71syce4n	204	19	still	still	ADV
cord-301856-71syce4n	204	20	scarce	scarce	ADJ
cord-301856-71syce4n	204	21	.	.	PUNCT
cord-301856-71syce4n	205	1	however	however	ADV
cord-301856-71syce4n	205	2	,	,	PUNCT
cord-301856-71syce4n	205	3	different	different	ADJ
cord-301856-71syce4n	205	4	experiences	experience	NOUN
cord-301856-71syce4n	205	5	undergone	undergo	VERB
cord-301856-71syce4n	205	6	by	by	ADP
cord-301856-71syce4n	205	7	certain	certain	ADJ
cord-301856-71syce4n	205	8	communities	community	NOUN
cord-301856-71syce4n	205	9	indicate	indicate	VERB
cord-301856-71syce4n	205	10	that	that	SCONJ
cord-301856-71syce4n	205	11	these	these	DET
cord-301856-71syce4n	205	12	mechanisms	mechanism	NOUN
cord-301856-71syce4n	205	13	might	might	AUX
cord-301856-71syce4n	205	14	be	be	AUX
cord-301856-71syce4n	205	15	important	important	ADJ
cord-301856-71syce4n	205	16	.	.	PUNCT
cord-301856-71syce4n	206	1	for	for	ADP
cord-301856-71syce4n	206	2	example	example	NOUN
cord-301856-71syce4n	206	3	,	,	PUNCT
cord-301856-71syce4n	206	4	the	the	DET
cord-301856-71syce4n	206	5	babies	baby	NOUN
cord-301856-71syce4n	206	6	of	of	ADP
cord-301856-71syce4n	206	7	pregnant	pregnant	ADJ
cord-301856-71syce4n	206	8	women	woman	NOUN
cord-301856-71syce4n	206	9	who	who	PRON
cord-301856-71syce4n	206	10	suffered	suffer	VERB
cord-301856-71syce4n	206	11	during	during	ADP
cord-301856-71syce4n	206	12	the	the	DET
cord-301856-71syce4n	206	13	early	early	ADJ
cord-301856-71syce4n	206	14	stages	stage	NOUN
cord-301856-71syce4n	206	15	of	of	ADP
cord-301856-71syce4n	206	16	pregnancy	pregnancy	NOUN
cord-301856-71syce4n	206	17	(	(	PUNCT
cord-301856-71syce4n	206	18	the	the	DET
cord-301856-71syce4n	206	19	effects	effect	NOUN
cord-301856-71syce4n	206	20	of	of	ADP
cord-301856-71syce4n	206	21	the	the	DET
cord-301856-71syce4n	206	22	dutch	dutch	ADJ
cord-301856-71syce4n	206	23	hunger	hunger	NOUN
cord-301856-71syce4n	206	24	winter	winter	NOUN
cord-301856-71syce4n	206	25	in	in	ADP
cord-301856-71syce4n	206	26	1944	1944	NUM
cord-301856-71syce4n	206	27	)	)	PUNCT
cord-301856-71syce4n	206	28	,	,	PUNCT
cord-301856-71syce4n	206	29	60	60	NUM
cord-301856-71syce4n	206	30	years	year	NOUN
cord-301856-71syce4n	206	31	later	later	ADV
cord-301856-71syce4n	206	32	showed	show	VERB
cord-301856-71syce4n	206	33	reduced	reduce	VERB
cord-301856-71syce4n	206	34	dna	dna	PROPN
cord-301856-71syce4n	206	35	methylation	methylation	NOUN
cord-301856-71syce4n	206	36	marks	mark	NOUN
cord-301856-71syce4n	206	37	in	in	ADP
cord-301856-71syce4n	206	38	several	several	ADJ
cord-301856-71syce4n	206	39	genes	gene	NOUN
cord-301856-71syce4n	206	40	that	that	PRON
cord-301856-71syce4n	206	41	control	control	VERB
cord-301856-71syce4n	206	42	metabolism	metabolism	NOUN
cord-301856-71syce4n	206	43	and	and	CCONJ
cord-301856-71syce4n	206	44	cell	cell	NOUN
cord-301856-71syce4n	206	45	differentiation	differentiation	NOUN
cord-301856-71syce4n	206	46	during	during	ADP
cord-301856-71syce4n	206	47	development	development	NOUN
cord-301856-71syce4n	206	48	,	,	PUNCT
cord-301856-71syce4n	206	49	such	such	ADJ
cord-301856-71syce4n	206	50	as	as	ADP
cord-301856-71syce4n	206	51	igf2	igf2	PROPN
cord-301856-71syce4n	206	52	,	,	PUNCT
cord-301856-71syce4n	206	53	pim3	pim3	PROPN
cord-301856-71syce4n	206	54	,	,	PUNCT
cord-301856-71syce4n	206	55	txnip	txnip	PROPN
cord-301856-71syce4n	206	56	,	,	PUNCT
cord-301856-71syce4n	206	57	abcg1	abcg1	NOUN
cord-301856-71syce4n	206	58	,	,	PUNCT
cord-301856-71syce4n	206	59	pfkfb3	pfkfb3	NUM
cord-301856-71syce4n	206	60	,	,	PUNCT
cord-301856-71syce4n	206	61	and	and	CCONJ
cord-301856-71syce4n	206	62	mettl8	mettl8	PROPN
cord-301856-71syce4n	206	63	,	,	PUNCT
cord-301856-71syce4n	206	64	compared	compare	VERB
cord-301856-71syce4n	206	65	with	with	ADP
cord-301856-71syce4n	206	66	their	their	PRON
cord-301856-71syce4n	206	67	siblings	sibling	NOUN
cord-301856-71syce4n	206	68	[	[	X
cord-301856-71syce4n	206	69	87	87	NUM
cord-301856-71syce4n	206	70	,	,	PUNCT
cord-301856-71syce4n	206	71	88	88	NUM
cord-301856-71syce4n	206	72	]	]	PUNCT
cord-301856-71syce4n	206	73	.	.	PUNCT
cord-301856-71syce4n	207	1	this	this	PRON
cord-301856-71syce4n	207	2	was	be	AUX
cord-301856-71syce4n	207	3	related	relate	VERB
cord-301856-71syce4n	207	4	with	with	ADP
cord-301856-71syce4n	207	5	higher	high	ADJ
cord-301856-71syce4n	207	6	rates	rate	NOUN
cord-301856-71syce4n	207	7	of	of	ADP
cord-301856-71syce4n	207	8	obesity	obesity	NOUN
cord-301856-71syce4n	207	9	,	,	PUNCT
cord-301856-71syce4n	207	10	heart	heart	NOUN
cord-301856-71syce4n	207	11	disease	disease	NOUN
cord-301856-71syce4n	207	12	,	,	PUNCT
cord-301856-71syce4n	207	13	cancer	cancer	NOUN
cord-301856-71syce4n	207	14	,	,	PUNCT
cord-301856-71syce4n	207	15	and	and	CCONJ
cord-301856-71syce4n	207	16	depression	depression	NOUN
cord-301856-71syce4n	207	17	in	in	ADP
cord-301856-71syce4n	207	18	individuals	individual	NOUN
cord-301856-71syce4n	207	19	whose	whose	DET
cord-301856-71syce4n	207	20	pregnant	pregnant	ADJ
cord-301856-71syce4n	207	21	mothers	mother	NOUN
cord-301856-71syce4n	207	22	suffered	suffer	VERB
cord-301856-71syce4n	207	23	the	the	DET
cord-301856-71syce4n	207	24	effects	effect	NOUN
cord-301856-71syce4n	207	25	of	of	ADP
cord-301856-71syce4n	207	26	the	the	DET
cord-301856-71syce4n	207	27	famine	famine	NOUN
cord-301856-71syce4n	207	28	[	[	X
cord-301856-71syce4n	207	29	87	87	NUM
cord-301856-71syce4n	207	30	,	,	PUNCT
cord-301856-71syce4n	207	31	88	88	NUM
cord-301856-71syce4n	207	32	]	]	PUNCT
cord-301856-71syce4n	207	33	.	.	PUNCT
cord-301856-71syce4n	208	1	some	some	PRON
cord-301856-71syce4n	208	2	of	of	ADP
cord-301856-71syce4n	208	3	these	these	DET
cord-301856-71syce4n	208	4	effects	effect	NOUN
cord-301856-71syce4n	208	5	seemed	seem	VERB
cord-301856-71syce4n	208	6	to	to	PART
cord-301856-71syce4n	208	7	be	be	AUX
cord-301856-71syce4n	208	8	present	present	ADJ
cord-301856-71syce4n	208	9	in	in	ADP
cord-301856-71syce4n	208	10	the	the	DET
cord-301856-71syce4n	208	11	progeny	progeny	NOUN
cord-301856-71syce4n	208	12	of	of	ADP
cord-301856-71syce4n	208	13	this	this	DET
cord-301856-71syce4n	208	14	group	group	NOUN
cord-301856-71syce4n	208	15	,	,	PUNCT
cord-301856-71syce4n	208	16	that	that	ADV
cord-301856-71syce4n	208	17	is	is	ADV
cord-301856-71syce4n	208	18	,	,	PUNCT
cord-301856-71syce4n	208	19	in	in	ADP
cord-301856-71syce4n	208	20	the	the	DET
cord-301856-71syce4n	208	21	grandchildren	grandchild	NOUN
cord-301856-71syce4n	208	22	of	of	ADP
cord-301856-71syce4n	208	23	those	those	PRON
cord-301856-71syce4n	208	24	who	who	PRON
cord-301856-71syce4n	208	25	had	have	AUX
cord-301856-71syce4n	208	26	passed	pass	VERB
cord-301856-71syce4n	208	27	the	the	DET
cord-301856-71syce4n	208	28	famine	famine	NOUN
cord-301856-71syce4n	208	29	during	during	ADP
cord-301856-71syce4n	208	30	pregnancy	pregnancy	NOUN
cord-301856-71syce4n	208	31	[	[	PUNCT
cord-301856-71syce4n	208	32	89	89	NUM
cord-301856-71syce4n	208	33	]	]	PUNCT
cord-301856-71syce4n	208	34	.	.	PUNCT
cord-301856-71syce4n	209	1	the	the	DET
cord-301856-71syce4n	209	2	rapid	rapid	ADJ
cord-301856-71syce4n	209	3	growth	growth	NOUN
cord-301856-71syce4n	209	4	in	in	ADP
cord-301856-71syce4n	209	5	the	the	DET
cord-301856-71syce4n	209	6	number	number	NOUN
cord-301856-71syce4n	209	7	of	of	ADP
cord-301856-71syce4n	209	8	reports	report	NOUN
cord-301856-71syce4n	209	9	covering	cover	VERB
cord-301856-71syce4n	209	10	the	the	DET
cord-301856-71syce4n	209	11	impact	impact	NOUN
cord-301856-71syce4n	209	12	of	of	ADP
cord-301856-71syce4n	209	13	epigenetic	epigenetic	ADJ
cord-301856-71syce4n	209	14	mechanisms	mechanism	NOUN
cord-301856-71syce4n	209	15	in	in	ADP
cord-301856-71syce4n	209	16	different	different	ADJ
cord-301856-71syce4n	209	17	human	human	ADJ
cord-301856-71syce4n	209	18	processes	process	NOUN
cord-301856-71syce4n	209	19	warrants	warrant	NOUN
cord-301856-71syce4n	209	20	further	further	ADJ
cord-301856-71syce4n	209	21	and	and	CCONJ
cord-301856-71syce4n	209	22	robust	robust	ADJ
cord-301856-71syce4n	209	23	studies	study	NOUN
cord-301856-71syce4n	209	24	on	on	ADP
cord-301856-71syce4n	209	25	the	the	DET
cord-301856-71syce4n	209	26	impact	impact	NOUN
cord-301856-71syce4n	209	27	of	of	ADP
cord-301856-71syce4n	209	28	epigenetic	epigenetic	ADJ
cord-301856-71syce4n	209	29	inheritance	inheritance	NOUN
cord-301856-71syce4n	209	30	in	in	ADP
cord-301856-71syce4n	209	31	shaping	shape	VERB
cord-301856-71syce4n	209	32	the	the	DET
cord-301856-71syce4n	209	33	evolution	evolution	NOUN
cord-301856-71syce4n	209	34	of	of	ADP
cord-301856-71syce4n	209	35	the	the	DET
cord-301856-71syce4n	209	36	human	human	ADJ
cord-301856-71syce4n	209	37	immune	immune	ADJ
cord-301856-71syce4n	209	38	system	system	NOUN
cord-301856-71syce4n	209	39	.	.	PUNCT
cord-301856-71syce4n	210	1	human	human	ADJ
cord-301856-71syce4n	210	2	immune	immune	ADJ
cord-301856-71syce4n	210	3	responses	response	NOUN
cord-301856-71syce4n	210	4	have	have	AUX
cord-301856-71syce4n	210	5	been	be	AUX
cord-301856-71syce4n	210	6	shaped	shape	VERB
cord-301856-71syce4n	210	7	by	by	ADP
cord-301856-71syce4n	210	8	the	the	DET
cord-301856-71syce4n	210	9	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	210	10	pressure	pressure	NOUN
cord-301856-71syce4n	210	11	exerted	exert	VERB
cord-301856-71syce4n	210	12	by	by	ADP
cord-301856-71syce4n	210	13	microorganisms	microorganism	NOUN
cord-301856-71syce4n	210	14	and	and	CCONJ
cord-301856-71syce4n	210	15	viruses	virus	NOUN
cord-301856-71syce4n	210	16	throughout	throughout	ADP
cord-301856-71syce4n	210	17	history	history	NOUN
cord-301856-71syce4n	210	18	.	.	PUNCT
cord-301856-71syce4n	211	1	generating	generate	VERB
cord-301856-71syce4n	211	2	a	a	DET
cord-301856-71syce4n	211	3	broad	broad	ADJ
cord-301856-71syce4n	211	4	range	range	NOUN
cord-301856-71syce4n	211	5	of	of	ADP
cord-301856-71syce4n	211	6	genetic	genetic	ADJ
cord-301856-71syce4n	211	7	variations	variation	NOUN
cord-301856-71syce4n	211	8	and	and	CCONJ
cord-301856-71syce4n	211	9	immune	immune	ADJ
cord-301856-71syce4n	211	10	functions	function	NOUN
cord-301856-71syce4n	211	11	in	in	ADP
cord-301856-71syce4n	211	12	different	different	ADJ
cord-301856-71syce4n	211	13	populations	population	NOUN
cord-301856-71syce4n	211	14	favors	favor	VERB
cord-301856-71syce4n	211	15	the	the	DET
cord-301856-71syce4n	211	16	adaptation	adaptation	NOUN
cord-301856-71syce4n	211	17	to	to	ADP
cord-301856-71syce4n	211	18	new	new	ADJ
cord-301856-71syce4n	211	19	environments	environment	NOUN
cord-301856-71syce4n	211	20	and	and	CCONJ
cord-301856-71syce4n	211	21	increases	increase	VERB
cord-301856-71syce4n	211	22	the	the	DET
cord-301856-71syce4n	211	23	chance	chance	NOUN
cord-301856-71syce4n	211	24	of	of	ADP
cord-301856-71syce4n	211	25	survival	survival	NOUN
cord-301856-71syce4n	211	26	of	of	ADP
cord-301856-71syce4n	211	27	the	the	DET
cord-301856-71syce4n	211	28	human	human	ADJ
cord-301856-71syce4n	211	29	species	specie	NOUN
cord-301856-71syce4n	211	30	against	against	ADP
cord-301856-71syce4n	211	31	potential	potential	ADJ
cord-301856-71syce4n	211	32	pandemics	pandemic	NOUN
cord-301856-71syce4n	211	33	.	.	PUNCT
cord-301856-71syce4n	212	1	much	much	ADJ
cord-301856-71syce4n	212	2	remains	remain	VERB
cord-301856-71syce4n	212	3	to	to	PART
cord-301856-71syce4n	212	4	be	be	AUX
cord-301856-71syce4n	212	5	learned	learn	VERB
cord-301856-71syce4n	212	6	in	in	ADP
cord-301856-71syce4n	212	7	this	this	DET
cord-301856-71syce4n	212	8	exciting	exciting	ADJ
cord-301856-71syce4n	212	9	field	field	NOUN
cord-301856-71syce4n	212	10	over	over	ADP
cord-301856-71syce4n	212	11	the	the	DET
cord-301856-71syce4n	212	12	coming	come	VERB
cord-301856-71syce4n	212	13	years	year	NOUN
cord-301856-71syce4n	212	14	in	in	ADP
cord-301856-71syce4n	212	15	order	order	NOUN
cord-301856-71syce4n	212	16	to	to	PART
cord-301856-71syce4n	212	17	identify	identify	VERB
cord-301856-71syce4n	212	18	the	the	DET
cord-301856-71syce4n	212	19	main	main	ADJ
cord-301856-71syce4n	212	20	regulatory	regulatory	ADJ
cord-301856-71syce4n	212	21	forces	force	NOUN
cord-301856-71syce4n	212	22	and	and	CCONJ
cord-301856-71syce4n	212	23	the	the	DET
cord-301856-71syce4n	212	24	time	time	NOUN
cord-301856-71syce4n	212	25	window	window	NOUN
cord-301856-71syce4n	212	26	necessary	necessary	ADJ
cord-301856-71syce4n	212	27	for	for	ADP
cord-301856-71syce4n	212	28	the	the	DET
cord-301856-71syce4n	212	29	fixation	fixation	NOUN
cord-301856-71syce4n	212	30	of	of	ADP
cord-301856-71syce4n	212	31	an	an	DET
cord-301856-71syce4n	212	32	advantageous	advantageous	ADJ
cord-301856-71syce4n	212	33	genetic	genetic	ADJ
cord-301856-71syce4n	212	34	trait	trait	NOUN
cord-301856-71syce4n	212	35	in	in	ADP
cord-301856-71syce4n	212	36	a	a	DET
cord-301856-71syce4n	212	37	population	population	NOUN
cord-301856-71syce4n	212	38	(	(	PUNCT
cord-301856-71syce4n	212	39	see	see	VERB
cord-301856-71syce4n	212	40	outstanding	outstanding	ADJ
cord-301856-71syce4n	212	41	questions	question	NOUN
cord-301856-71syce4n	212	42	)	)	PUNCT
cord-301856-71syce4n	212	43	.	.	PUNCT
cord-301856-71syce4n	213	1	the	the	DET
cord-301856-71syce4n	213	2	combination	combination	NOUN
cord-301856-71syce4n	213	3	of	of	ADP
cord-301856-71syce4n	213	4	the	the	DET
cord-301856-71syce4n	213	5	selective	selective	ADJ
cord-301856-71syce4n	213	6	pressure	pressure	NOUN
cord-301856-71syce4n	213	7	caused	cause	VERB
cord-301856-71syce4n	213	8	by	by	ADP
cord-301856-71syce4n	213	9	infectious	infectious	ADJ
cord-301856-71syce4n	213	10	diseases	disease	NOUN
cord-301856-71syce4n	213	11	with	with	ADP
cord-301856-71syce4n	213	12	other	other	ADJ
cord-301856-71syce4n	213	13	evolutionarily	evolutionarily	ADV
cord-301856-71syce4n	213	14	relevant	relevant	ADJ
cord-301856-71syce4n	213	15	processes	process	NOUN
cord-301856-71syce4n	213	16	,	,	PUNCT
cord-301856-71syce4n	213	17	such	such	ADJ
cord-301856-71syce4n	213	18	as	as	ADP
cord-301856-71syce4n	213	19	genetic	genetic	ADJ
cord-301856-71syce4n	213	20	drift	drift	NOUN
cord-301856-71syce4n	213	21	,	,	PUNCT
cord-301856-71syce4n	213	22	migratory	migratory	ADJ
cord-301856-71syce4n	213	23	events	event	NOUN
cord-301856-71syce4n	213	24	,	,	PUNCT
cord-301856-71syce4n	213	25	bottlenecks	bottleneck	NOUN
cord-301856-71syce4n	213	26	,	,	PUNCT
cord-301856-71syce4n	213	27	and	and	CCONJ
cord-301856-71syce4n	213	28	introgressive	introgressive	PROPN
cord-301856-71syce4n	213	29	hybridization	hybridization	PROPN
cord-301856-71syce4n	213	30	,	,	PUNCT
cord-301856-71syce4n	213	31	contribute	contribute	VERB
cord-301856-71syce4n	213	32	to	to	ADP
cord-301856-71syce4n	213	33	driving	drive	VERB
cord-301856-71syce4n	213	34	the	the	DET
cord-301856-71syce4n	213	35	expansion	expansion	NOUN
cord-301856-71syce4n	213	36	,	,	PUNCT
cord-301856-71syce4n	213	37	fixation	fixation	NOUN
cord-301856-71syce4n	213	38	,	,	PUNCT
cord-301856-71syce4n	213	39	or	or	CCONJ
cord-301856-71syce4n	213	40	elimination	elimination	NOUN
cord-301856-71syce4n	213	41	of	of	ADP
cord-301856-71syce4n	213	42	characteristic	characteristic	ADJ
cord-301856-71syce4n	213	43	immune	immune	ADJ
cord-301856-71syce4n	213	44	response	response	NOUN
cord-301856-71syce4n	213	45	-	-	PUNCT
cord-301856-71syce4n	213	46	related	relate	VERB
cord-301856-71syce4n	213	47	traits	trait	NOUN
cord-301856-71syce4n	213	48	in	in	ADP
cord-301856-71syce4n	213	49	different	different	ADJ
cord-301856-71syce4n	213	50	populations	population	NOUN
cord-301856-71syce4n	213	51	around	around	ADP
cord-301856-71syce4n	213	52	the	the	DET
cord-301856-71syce4n	213	53	world	world	NOUN
cord-301856-71syce4n	213	54	.	.	PUNCT
cord-301856-71syce4n	214	1	these	these	DET
cord-301856-71syce4n	214	2	specific	specific	ADJ
cord-301856-71syce4n	214	3	genetic	genetic	ADJ
cord-301856-71syce4n	214	4	variants	variant	NOUN
cord-301856-71syce4n	214	5	are	be	AUX
cord-301856-71syce4n	214	6	able	able	ADJ
cord-301856-71syce4n	214	7	to	to	PART
cord-301856-71syce4n	214	8	boost	boost	VERB
cord-301856-71syce4n	214	9	the	the	DET
cord-301856-71syce4n	214	10	host	host	NOUN
cord-301856-71syce4n	214	11	response	response	NOUN
cord-301856-71syce4n	214	12	against	against	ADP
cord-301856-71syce4n	214	13	pathogens	pathogen	NOUN
cord-301856-71syce4n	214	14	by	by	ADP
cord-301856-71syce4n	214	15	improving	improve	VERB
cord-301856-71syce4n	214	16	the	the	DET
cord-301856-71syce4n	214	17	sensing	sensing	NOUN
cord-301856-71syce4n	214	18	of	of	ADP
cord-301856-71syce4n	214	19	microbial	microbial	ADJ
cord-301856-71syce4n	214	20	ligands	ligand	NOUN
cord-301856-71syce4n	214	21	but	but	CCONJ
cord-301856-71syce4n	214	22	can	can	AUX
cord-301856-71syce4n	214	23	also	also	ADV
cord-301856-71syce4n	214	24	lead	lead	VERB
cord-301856-71syce4n	214	25	to	to	ADP
cord-301856-71syce4n	214	26	the	the	DET
cord-301856-71syce4n	214	27	development	development	NOUN
cord-301856-71syce4n	214	28	of	of	ADP
cord-301856-71syce4n	214	29	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	214	30	diseases	disease	NOUN
cord-301856-71syce4n	214	31	,	,	PUNCT
cord-301856-71syce4n	214	32	in	in	ADP
cord-301856-71syce4n	214	33	which	which	PRON
cord-301856-71syce4n	214	34	the	the	DET
cord-301856-71syce4n	214	35	immune	immune	ADJ
cord-301856-71syce4n	214	36	system	system	NOUN
cord-301856-71syce4n	214	37	responds	respond	VERB
cord-301856-71syce4n	214	38	to	to	ADP
cord-301856-71syce4n	214	39	endogenous	endogenous	ADJ
cord-301856-71syce4n	214	40	ligands	ligand	NOUN
cord-301856-71syce4n	214	41	and	and	CCONJ
cord-301856-71syce4n	214	42	induces	induce	VERB
cord-301856-71syce4n	214	43	abnormal	abnormal	ADJ
cord-301856-71syce4n	214	44	responses	response	NOUN
cord-301856-71syce4n	214	45	targeted	target	VERB
cord-301856-71syce4n	214	46	against	against	ADP
cord-301856-71syce4n	214	47	the	the	DET
cord-301856-71syce4n	214	48	host	host	NOUN
cord-301856-71syce4n	214	49	's	's	PART
cord-301856-71syce4n	214	50	own	own	ADJ
cord-301856-71syce4n	214	51	tissues	tissue	NOUN
cord-301856-71syce4n	214	52	.	.	PUNCT
cord-301856-71syce4n	215	1	of	of	ADP
cord-301856-71syce4n	215	2	note	note	NOUN
cord-301856-71syce4n	215	3	,	,	PUNCT
cord-301856-71syce4n	215	4	it	it	PRON
cord-301856-71syce4n	215	5	is	be	AUX
cord-301856-71syce4n	215	6	very	very	ADV
cord-301856-71syce4n	215	7	difficult	difficult	ADJ
cord-301856-71syce4n	215	8	to	to	PART
cord-301856-71syce4n	215	9	assign	assign	VERB
cord-301856-71syce4n	215	10	certain	certain	ADJ
cord-301856-71syce4n	215	11	variants	variant	NOUN
cord-301856-71syce4n	215	12	,	,	PUNCT
cord-301856-71syce4n	215	13	a	a	DET
cord-301856-71syce4n	215	14	specific	specific	ADJ
cord-301856-71syce4n	215	15	role	role	NOUN
cord-301856-71syce4n	215	16	in	in	ADP
cord-301856-71syce4n	215	17	the	the	DET
cord-301856-71syce4n	215	18	protection	protection	NOUN
cord-301856-71syce4n	215	19	or	or	CCONJ
cord-301856-71syce4n	215	20	induction	induction	NOUN
cord-301856-71syce4n	215	21	of	of	ADP
cord-301856-71syce4n	215	22	autoimmunity	autoimmunity	NOUN
cord-301856-71syce4n	215	23	.	.	PUNCT
cord-301856-71syce4n	216	1	to	to	PART
cord-301856-71syce4n	216	2	assign	assign	VERB
cord-301856-71syce4n	216	3	changes	change	NOUN
cord-301856-71syce4n	216	4	in	in	ADP
cord-301856-71syce4n	216	5	the	the	DET
cord-301856-71syce4n	216	6	genetic	genetic	ADJ
cord-301856-71syce4n	216	7	landscape	landscape	NOUN
cord-301856-71syce4n	216	8	of	of	ADP
cord-301856-71syce4n	216	9	human	human	ADJ
cord-301856-71syce4n	216	10	populations	population	NOUN
cord-301856-71syce4n	216	11	to	to	ADP
cord-301856-71syce4n	216	12	certain	certain	ADJ
cord-301856-71syce4n	216	13	diseases	disease	NOUN
cord-301856-71syce4n	216	14	is	be	AUX
cord-301856-71syce4n	216	15	an	an	DET
cord-301856-71syce4n	216	16	extraordinary	extraordinary	ADJ
cord-301856-71syce4n	216	17	challenge	challenge	NOUN
cord-301856-71syce4n	216	18	.	.	PUNCT
cord-301856-71syce4n	217	1	moreover	moreover	ADV
cord-301856-71syce4n	217	2	,	,	PUNCT
cord-301856-71syce4n	217	3	our	our	PRON
cord-301856-71syce4n	217	4	species	specie	NOUN
cord-301856-71syce4n	217	5	is	be	AUX
cord-301856-71syce4n	217	6	in	in	ADP
cord-301856-71syce4n	217	7	constant	constant	ADJ
cord-301856-71syce4n	217	8	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	217	9	interaction	interaction	NOUN
cord-301856-71syce4n	217	10	with	with	ADP
cord-301856-71syce4n	217	11	various	various	ADJ
cord-301856-71syce4n	217	12	microorganisms	microorganism	NOUN
cord-301856-71syce4n	217	13	and	and	CCONJ
cord-301856-71syce4n	217	14	viruses	virus	NOUN
cord-301856-71syce4n	217	15	.	.	PUNCT
cord-301856-71syce4n	218	1	populations	population	NOUN
cord-301856-71syce4n	218	2	of	of	ADP
cord-301856-71syce4n	218	3	bacteria	bacteria	NOUN
cord-301856-71syce4n	218	4	and	and	CCONJ
cord-301856-71syce4n	218	5	their	their	PRON
cord-301856-71syce4n	218	6	viruses	virus	NOUN
cord-301856-71syce4n	218	7	(	(	PUNCT
cord-301856-71syce4n	218	8	phages	phage	NOUN
cord-301856-71syce4n	218	9	)	)	PUNCT
cord-301856-71syce4n	218	10	undergo	undergo	VERB
cord-301856-71syce4n	218	11	,	,	PUNCT
cord-301856-71syce4n	218	12	under	under	ADP
cord-301856-71syce4n	218	13	natural	natural	ADJ
cord-301856-71syce4n	218	14	conditions	condition	NOUN
cord-301856-71syce4n	218	15	,	,	PUNCT
cord-301856-71syce4n	218	16	reciprocal	reciprocal	ADJ
cord-301856-71syce4n	218	17	evolution	evolution	NOUN
cord-301856-71syce4n	218	18	in	in	ADP
cord-301856-71syce4n	218	19	terms	term	NOUN
cord-301856-71syce4n	218	20	of	of	ADP
cord-301856-71syce4n	218	21	resistance	resistance	NOUN
cord-301856-71syce4n	218	22	and	and	CCONJ
cord-301856-71syce4n	218	23	infection	infection	NOUN
cord-301856-71syce4n	218	24	;	;	PUNCT
cord-301856-71syce4n	218	25	this	this	PRON
cord-301856-71syce4n	218	26	,	,	PUNCT
cord-301856-71syce4n	218	27	in	in	ADP
cord-301856-71syce4n	218	28	turn	turn	NOUN
cord-301856-71syce4n	218	29	,	,	PUNCT
cord-301856-71syce4n	218	30	also	also	ADV
cord-301856-71syce4n	218	31	affects	affect	VERB
cord-301856-71syce4n	218	32	the	the	DET
cord-301856-71syce4n	218	33	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	218	34	traits	trait	NOUN
cord-301856-71syce4n	218	35	of	of	ADP
cord-301856-71syce4n	218	36	our	our	PRON
cord-301856-71syce4n	218	37	immune	immune	ADJ
cord-301856-71syce4n	218	38	system	system	NOUN
cord-301856-71syce4n	218	39	.	.	PUNCT
cord-301856-71syce4n	219	1	thus	thus	ADV
cord-301856-71syce4n	219	2	,	,	PUNCT
cord-301856-71syce4n	219	3	an	an	DET
cord-301856-71syce4n	219	4	extraordinarily	extraordinarily	ADV
cord-301856-71syce4n	219	5	complex	complex	ADJ
cord-301856-71syce4n	219	6	scenario	scenario	NOUN
cord-301856-71syce4n	219	7	exists	exist	VERB
cord-301856-71syce4n	219	8	in	in	ADP
cord-301856-71syce4n	219	9	which	which	PRON
cord-301856-71syce4n	219	10	organisms	organism	NOUN
cord-301856-71syce4n	219	11	of	of	ADP
cord-301856-71syce4n	219	12	different	different	ADJ
cord-301856-71syce4n	219	13	phyla	phyla	NOUN
cord-301856-71syce4n	219	14	interact	interact	NOUN
cord-301856-71syce4n	219	15	,	,	PUNCT
cord-301856-71syce4n	219	16	compete	compete	VERB
cord-301856-71syce4n	219	17	,	,	PUNCT
cord-301856-71syce4n	219	18	and	and	CCONJ
cord-301856-71syce4n	219	19	coevolve	coevolve	NOUN
cord-301856-71syce4n	219	20	,	,	PUNCT
cord-301856-71syce4n	219	21	to	to	PART
cord-301856-71syce4n	219	22	ensure	ensure	VERB
cord-301856-71syce4n	219	23	their	their	PRON
cord-301856-71syce4n	219	24	own	own	ADJ
cord-301856-71syce4n	219	25	survival	survival	NOUN
cord-301856-71syce4n	219	26	.	.	PUNCT
cord-301856-71syce4n	220	1	as	as	ADP
cord-301856-71syce4n	220	2	novel	novel	ADJ
cord-301856-71syce4n	220	3	tools	tool	NOUN
cord-301856-71syce4n	220	4	,	,	PUNCT
cord-301856-71syce4n	220	5	the	the	DET
cord-301856-71syce4n	220	6	development	development	NOUN
cord-301856-71syce4n	220	7	and	and	CCONJ
cord-301856-71syce4n	220	8	refinement	refinement	NOUN
cord-301856-71syce4n	220	9	of	of	ADP
cord-301856-71syce4n	220	10	methods	method	NOUN
cord-301856-71syce4n	220	11	that	that	PRON
cord-301856-71syce4n	220	12	study	study	VERB
cord-301856-71syce4n	220	13	large	large	ADJ
cord-301856-71syce4n	220	14	sections	section	NOUN
cord-301856-71syce4n	220	15	of	of	ADP
cord-301856-71syce4n	220	16	the	the	DET
cord-301856-71syce4n	220	17	human	human	ADJ
cord-301856-71syce4n	220	18	genome	genome	NOUN
cord-301856-71syce4n	220	19	,	,	PUNCT
cord-301856-71syce4n	220	20	epigenome	epigenome	NOUN
cord-301856-71syce4n	220	21	,	,	PUNCT
cord-301856-71syce4n	220	22	and	and	CCONJ
cord-301856-71syce4n	220	23	microbiota	microbiota	NOUN
cord-301856-71syce4n	220	24	,	,	PUNCT
cord-301856-71syce4n	220	25	will	will	AUX
cord-301856-71syce4n	220	26	help	help	VERB
cord-301856-71syce4n	220	27	to	to	PART
cord-301856-71syce4n	220	28	obtain	obtain	VERB
cord-301856-71syce4n	220	29	genome	genome	NOUN
cord-301856-71syce4n	220	30	-	-	PUNCT
cord-301856-71syce4n	220	31	wide	wide	ADJ
cord-301856-71syce4n	220	32	data	datum	NOUN
cord-301856-71syce4n	220	33	in	in	ADP
cord-301856-71syce4n	220	34	diverse	diverse	ADJ
cord-301856-71syce4n	220	35	human	human	ADJ
cord-301856-71syce4n	220	36	populations	population	NOUN
cord-301856-71syce4n	220	37	,	,	PUNCT
cord-301856-71syce4n	220	38	allowing	allow	VERB
cord-301856-71syce4n	220	39	us	we	PRON
cord-301856-71syce4n	220	40	to	to	PART
cord-301856-71syce4n	220	41	follow	follow	VERB
cord-301856-71syce4n	220	42	the	the	DET
cord-301856-71syce4n	220	43	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	220	44	trails	trail	NOUN
cord-301856-71syce4n	220	45	left	leave	VERB
cord-301856-71syce4n	220	46	from	from	ADP
cord-301856-71syce4n	220	47	the	the	DET
cord-301856-71syce4n	220	48	encounters	encounter	NOUN
cord-301856-71syce4n	220	49	with	with	ADP
cord-301856-71syce4n	220	50	different	different	ADJ
cord-301856-71syce4n	220	51	organisms	organism	NOUN
cord-301856-71syce4n	220	52	,	,	PUNCT
cord-301856-71syce4n	220	53	further	far	ADV
cord-301856-71syce4n	220	54	unveiling	unveil	VERB
cord-301856-71syce4n	220	55	the	the	DET
cord-301856-71syce4n	220	56	roots	root	NOUN
cord-301856-71syce4n	220	57	of	of	ADP
cord-301856-71syce4n	220	58	human	human	ADJ
cord-301856-71syce4n	220	59	immunity	immunity	NOUN
cord-301856-71syce4n	220	60	.	.	PUNCT
cord-301856-71syce4n	221	1	high	high	ADJ
cord-301856-71syce4n	221	2	-	-	PUNCT
cord-301856-71syce4n	221	3	throughput	throughput	NOUN
cord-301856-71syce4n	221	4	biotechnology	biotechnology	NOUN
cord-301856-71syce4n	221	5	and	and	CCONJ
cord-301856-71syce4n	221	6	an	an	DET
cord-301856-71syce4n	221	7	expanding	expand	VERB
cord-301856-71syce4n	221	8	computational	computational	ADJ
cord-301856-71syce4n	221	9	capacity	capacity	NOUN
cord-301856-71syce4n	221	10	can	can	AUX
cord-301856-71syce4n	221	11	enable	enable	VERB
cord-301856-71syce4n	221	12	the	the	DET
cord-301856-71syce4n	221	13	study	study	NOUN
cord-301856-71syce4n	221	14	of	of	ADP
cord-301856-71syce4n	221	15	global	global	ADJ
cord-301856-71syce4n	221	16	population	population	NOUN
cord-301856-71syce4n	221	17	genomics	genomic	NOUN
cord-301856-71syce4n	221	18	and	and	CCONJ
cord-301856-71syce4n	221	19	might	might	AUX
cord-301856-71syce4n	221	20	contribute	contribute	VERB
cord-301856-71syce4n	221	21	to	to	ADP
cord-301856-71syce4n	221	22	decoding	decode	VERB
cord-301856-71syce4n	221	23	the	the	DET
cord-301856-71syce4n	221	24	origin	origin	NOUN
cord-301856-71syce4n	221	25	and	and	CCONJ
cord-301856-71syce4n	221	26	consequences	consequence	NOUN
cord-301856-71syce4n	221	27	of	of	ADP
cord-301856-71syce4n	221	28	functional	functional	ADJ
cord-301856-71syce4n	221	29	changes	change	NOUN
cord-301856-71syce4n	221	30	in	in	ADP
cord-301856-71syce4n	221	31	adaptive	adaptive	ADJ
cord-301856-71syce4n	221	32	alleles	allele	NOUN
cord-301856-71syce4n	221	33	down	down	ADP
cord-301856-71syce4n	221	34	to	to	ADP
cord-301856-71syce4n	221	35	the	the	DET
cord-301856-71syce4n	221	36	single	single	ADJ
cord-301856-71syce4n	221	37	cell	cell	NOUN
cord-301856-71syce4n	221	38	level	level	NOUN
cord-301856-71syce4n	221	39	.	.	PUNCT
cord-301856-71syce4n	222	1	however	however	ADV
cord-301856-71syce4n	222	2	,	,	PUNCT
cord-301856-71syce4n	222	3	these	these	DET
cord-301856-71syce4n	222	4	methods	method	NOUN
cord-301856-71syce4n	222	5	also	also	ADV
cord-301856-71syce4n	222	6	have	have	VERB
cord-301856-71syce4n	222	7	limitations	limitation	NOUN
cord-301856-71syce4n	222	8	associated	associate	VERB
cord-301856-71syce4n	222	9	with	with	ADP
cord-301856-71syce4n	222	10	the	the	DET
cord-301856-71syce4n	222	11	difficulty	difficulty	NOUN
cord-301856-71syce4n	222	12	in	in	ADP
cord-301856-71syce4n	222	13	linking	link	VERB
cord-301856-71syce4n	222	14	gene	gene	NOUN
cord-301856-71syce4n	222	15	variations	variation	NOUN
cord-301856-71syce4n	222	16	to	to	ADP
cord-301856-71syce4n	222	17	clinical	clinical	ADJ
cord-301856-71syce4n	222	18	phenotypes	phenotype	NOUN
cord-301856-71syce4n	222	19	and	and	CCONJ
cord-301856-71syce4n	222	20	disease	disease	NOUN
cord-301856-71syce4n	222	21	,	,	PUNCT
cord-301856-71syce4n	222	22	the	the	DET
cord-301856-71syce4n	222	23	generation	generation	NOUN
cord-301856-71syce4n	222	24	of	of	ADP
cord-301856-71syce4n	222	25	false	false	ADJ
cord-301856-71syce4n	222	26	positives	positive	NOUN
cord-301856-71syce4n	222	27	,	,	PUNCT
cord-301856-71syce4n	222	28	or	or	CCONJ
cord-301856-71syce4n	222	29	the	the	DET
cord-301856-71syce4n	222	30	high	high	ADJ
cord-301856-71syce4n	222	31	number	number	NOUN
cord-301856-71syce4n	222	32	of	of	ADP
cord-301856-71syce4n	222	33	samples	sample	NOUN
cord-301856-71syce4n	222	34	necessary	necessary	ADJ
cord-301856-71syce4n	222	35	to	to	PART
cord-301856-71syce4n	222	36	reach	reach	VERB
cord-301856-71syce4n	222	37	reliable	reliable	ADJ
cord-301856-71syce4n	222	38	conclusions	conclusion	NOUN
cord-301856-71syce4n	222	39	.	.	PUNCT
cord-301856-71syce4n	223	1	expanding	expand	VERB
cord-301856-71syce4n	223	2	the	the	DET
cord-301856-71syce4n	223	3	heterogeneity	heterogeneity	NOUN
cord-301856-71syce4n	223	4	of	of	ADP
cord-301856-71syce4n	223	5	populations	population	NOUN
cord-301856-71syce4n	223	6	studied	study	VERB
cord-301856-71syce4n	223	7	for	for	ADP
cord-301856-71syce4n	223	8	immune	immune	ADJ
cord-301856-71syce4n	223	9	gene	gene	NOUN
cord-301856-71syce4n	223	10	association	association	NOUN
cord-301856-71syce4n	223	11	studies	study	NOUN
cord-301856-71syce4n	223	12	relevant	relevant	ADJ
cord-301856-71syce4n	223	13	to	to	ADP
cord-301856-71syce4n	223	14	disease	disease	NOUN
cord-301856-71syce4n	223	15	will	will	AUX
cord-301856-71syce4n	223	16	be	be	AUX
cord-301856-71syce4n	223	17	key	key	ADJ
cord-301856-71syce4n	223	18	,	,	PUNCT
cord-301856-71syce4n	223	19	as	as	ADV
cord-301856-71syce4n	223	20	generally	generally	ADV
cord-301856-71syce4n	223	21	,	,	PUNCT
cord-301856-71syce4n	223	22	a	a	DET
cord-301856-71syce4n	223	23	large	large	ADJ
cord-301856-71syce4n	223	24	focus	focus	NOUN
cord-301856-71syce4n	223	25	is	be	AUX
cord-301856-71syce4n	223	26	placed	place	VERB
cord-301856-71syce4n	223	27	on	on	ADP
cord-301856-71syce4n	223	28	certain	certain	ADJ
cord-301856-71syce4n	223	29	european	european	ADJ
cord-301856-71syce4n	223	30	or	or	CCONJ
cord-301856-71syce4n	223	31	american	american	ADJ
cord-301856-71syce4n	223	32	communities	community	NOUN
cord-301856-71syce4n	223	33	,	,	PUNCT
cord-301856-71syce4n	223	34	thus	thus	ADV
cord-301856-71syce4n	223	35	generating	generate	VERB
cord-301856-71syce4n	223	36	results	result	NOUN
cord-301856-71syce4n	223	37	that	that	PRON
cord-301856-71syce4n	223	38	are	be	AUX
cord-301856-71syce4n	223	39	difficult	difficult	ADJ
cord-301856-71syce4n	223	40	to	to	PART
cord-301856-71syce4n	223	41	extrapolate	extrapolate	VERB
cord-301856-71syce4n	223	42	to	to	ADP
cord-301856-71syce4n	223	43	other	other	ADJ
cord-301856-71syce4n	223	44	populations	population	NOUN
cord-301856-71syce4n	223	45	.	.	PUNCT
cord-301856-71syce4n	224	1	the	the	DET
cord-301856-71syce4n	224	2	knowledge	knowledge	NOUN
cord-301856-71syce4n	224	3	of	of	ADP
cord-301856-71syce4n	224	4	the	the	DET
cord-301856-71syce4n	224	5	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	224	6	and	and	CCONJ
cord-301856-71syce4n	224	7	genetic	genetic	ADJ
cord-301856-71syce4n	224	8	basis	basis	NOUN
cord-301856-71syce4n	224	9	of	of	ADP
cord-301856-71syce4n	224	10	human	human	ADJ
cord-301856-71syce4n	224	11	immune	immune	ADJ
cord-301856-71syce4n	224	12	traits	trait	NOUN
cord-301856-71syce4n	224	13	and	and	CCONJ
cord-301856-71syce4n	224	14	their	their	PRON
cord-301856-71syce4n	224	15	impact	impact	NOUN
cord-301856-71syce4n	224	16	on	on	ADP
cord-301856-71syce4n	224	17	diverse	diverse	ADJ
cord-301856-71syce4n	224	18	pathologies	pathology	NOUN
cord-301856-71syce4n	224	19	(	(	PUNCT
cord-301856-71syce4n	224	20	e.g.	e.g.	ADV
cord-301856-71syce4n	224	21	,	,	PUNCT
cord-301856-71syce4n	224	22	autoimmunity	autoimmunity	NOUN
cord-301856-71syce4n	224	23	,	,	PUNCT
cord-301856-71syce4n	224	24	infections	infection	NOUN
cord-301856-71syce4n	224	25	,	,	PUNCT
cord-301856-71syce4n	224	26	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	224	27	diseases	disease	NOUN
cord-301856-71syce4n	224	28	,	,	PUNCT
cord-301856-71syce4n	224	29	cancer	cancer	NOUN
cord-301856-71syce4n	224	30	)	)	PUNCT
cord-301856-71syce4n	224	31	increasingly	increasingly	ADV
cord-301856-71syce4n	224	32	suggests	suggest	VERB
cord-301856-71syce4n	224	33	that	that	SCONJ
cord-301856-71syce4n	224	34	the	the	DET
cord-301856-71syce4n	224	35	genetic	genetic	ADJ
cord-301856-71syce4n	224	36	basis	basis	NOUN
cord-301856-71syce4n	224	37	of	of	ADP
cord-301856-71syce4n	224	38	disease	disease	NOUN
cord-301856-71syce4n	224	39	may	may	AUX
cord-301856-71syce4n	224	40	be	be	AUX
cord-301856-71syce4n	224	41	derived	derive	VERB
cord-301856-71syce4n	224	42	from	from	ADP
cord-301856-71syce4n	224	43	a	a	DET
cord-301856-71syce4n	224	44	large	large	ADJ
cord-301856-71syce4n	224	45	number	number	NOUN
cord-301856-71syce4n	224	46	of	of	ADP
cord-301856-71syce4n	224	47	rare	rare	ADJ
cord-301856-71syce4n	224	48	variants	variant	NOUN
cord-301856-71syce4n	224	49	of	of	ADP
cord-301856-71syce4n	224	50	modest	modest	ADJ
cord-301856-71syce4n	224	51	effect	effect	NOUN
cord-301856-71syce4n	224	52	.	.	PUNCT
cord-301856-71syce4n	225	1	the	the	DET
cord-301856-71syce4n	225	2	mechanisms	mechanism	NOUN
cord-301856-71syce4n	225	3	described	describe	VERB
cord-301856-71syce4n	225	4	here	here	ADV
cord-301856-71syce4n	225	5	acquire	acquire	VERB
cord-301856-71syce4n	225	6	special	special	ADJ
cord-301856-71syce4n	225	7	importance	importance	NOUN
cord-301856-71syce4n	225	8	in	in	ADP
cord-301856-71syce4n	225	9	the	the	DET
cord-301856-71syce4n	225	10	current	current	ADJ
cord-301856-71syce4n	225	11	scenario	scenario	NOUN
cord-301856-71syce4n	225	12	of	of	ADP
cord-301856-71syce4n	225	13	world	world	NOUN
cord-301856-71syce4n	225	14	globalization	globalization	NOUN
cord-301856-71syce4n	225	15	,	,	PUNCT
cord-301856-71syce4n	225	16	in	in	ADP
cord-301856-71syce4n	225	17	which	which	PRON
cord-301856-71syce4n	225	18	the	the	DET
cord-301856-71syce4n	225	19	migration	migration	NOUN
cord-301856-71syce4n	225	20	fluxes	flux	NOUN
cord-301856-71syce4n	225	21	and	and	CCONJ
cord-301856-71syce4n	225	22	the	the	DET
cord-301856-71syce4n	225	23	admixture	admixture	NOUN
cord-301856-71syce4n	225	24	of	of	ADP
cord-301856-71syce4n	225	25	different	different	ADJ
cord-301856-71syce4n	225	26	populations	population	NOUN
cord-301856-71syce4n	225	27	are	be	AUX
cord-301856-71syce4n	225	28	reaching	reach	VERB
cord-301856-71syce4n	225	29	unprecedented	unprecedented	ADJ
cord-301856-71syce4n	225	30	levels	level	NOUN
cord-301856-71syce4n	225	31	,	,	PUNCT
cord-301856-71syce4n	225	32	allowing	allow	VERB
cord-301856-71syce4n	225	33	faster	fast	ADJ
cord-301856-71syce4n	225	34	expansion	expansion	NOUN
cord-301856-71syce4n	225	35	of	of	ADP
cord-301856-71syce4n	225	36	advantageous	advantageous	ADJ
cord-301856-71syce4n	225	37	alleles	allele	NOUN
cord-301856-71syce4n	225	38	.	.	PUNCT
cord-301856-71syce4n	226	1	however	however	ADV
cord-301856-71syce4n	226	2	,	,	PUNCT
cord-301856-71syce4n	226	3	these	these	DET
cord-301856-71syce4n	226	4	processes	process	NOUN
cord-301856-71syce4n	226	5	may	may	AUX
cord-301856-71syce4n	226	6	also	also	ADV
cord-301856-71syce4n	226	7	accelerate	accelerate	VERB
cord-301856-71syce4n	226	8	the	the	DET
cord-301856-71syce4n	226	9	spread	spread	NOUN
cord-301856-71syce4n	226	10	of	of	ADP
cord-301856-71syce4n	226	11	new	new	ADJ
cord-301856-71syce4n	226	12	epidemics	epidemic	NOUN
cord-301856-71syce4n	226	13	,	,	PUNCT
cord-301856-71syce4n	226	14	as	as	SCONJ
cord-301856-71syce4n	226	15	seen	see	VERB
cord-301856-71syce4n	226	16	in	in	ADP
cord-301856-71syce4n	226	17	the	the	DET
cord-301856-71syce4n	226	18	cases	case	NOUN
cord-301856-71syce4n	226	19	of	of	ADP
cord-301856-71syce4n	226	20	hiv	hiv	PROPN
cord-301856-71syce4n	226	21	infection	infection	NOUN
cord-301856-71syce4n	226	22	,	,	PUNCT
cord-301856-71syce4n	226	23	or	or	CCONJ
cord-301856-71syce4n	226	24	more	more	ADV
cord-301856-71syce4n	226	25	recently	recently	ADV
cord-301856-71syce4n	226	26	,	,	PUNCT
cord-301856-71syce4n	226	27	sars	sars	PROPN
cord-301856-71syce4n	226	28	-	-	PUNCT
cord-301856-71syce4n	226	29	cov	cov	PROPN
cord-301856-71syce4n	226	30	,	,	PUNCT
cord-301856-71syce4n	226	31	ebola	ebola	PROPN
cord-301856-71syce4n	226	32	,	,	PUNCT
cord-301856-71syce4n	226	33	and	and	CCONJ
cord-301856-71syce4n	226	34	chikungunya	chikungunya	NOUN
cord-301856-71syce4n	226	35	viruses	virus	NOUN
cord-301856-71syce4n	226	36	;	;	PUNCT
cord-301856-71syce4n	226	37	as	as	ADV
cord-301856-71syce4n	226	38	well	well	ADV
cord-301856-71syce4n	226	39	as	as	ADP
cord-301856-71syce4n	226	40	the	the	DET
cord-301856-71syce4n	226	41	emergence	emergence	NOUN
cord-301856-71syce4n	226	42	of	of	ADP
cord-301856-71syce4n	226	43	multiresistant	multiresistant	ADJ
cord-301856-71syce4n	226	44	bacteria	bacteria	NOUN
cord-301856-71syce4n	226	45	and	and	CCONJ
cord-301856-71syce4n	226	46	fungi	fungi	PROPN
cord-301856-71syce4n	226	47	,	,	PUNCT
cord-301856-71syce4n	226	48	such	such	ADJ
cord-301856-71syce4n	226	49	as	as	ADP
cord-301856-71syce4n	226	50	methicillin	methicillin	NOUN
cord-301856-71syce4n	226	51	-	-	PUNCT
cord-301856-71syce4n	226	52	resistant	resistant	ADJ
cord-301856-71syce4n	226	53	s.	s.	PROPN
cord-301856-71syce4n	226	54	aureus	aureus	PROPN
cord-301856-71syce4n	226	55	or	or	CCONJ
cord-301856-71syce4n	226	56	candida	candida	PROPN
cord-301856-71syce4n	226	57	auris	auris	PROPN
cord-301856-71syce4n	226	58	.	.	PUNCT
cord-301856-71syce4n	227	1	this	this	PRON
cord-301856-71syce4n	227	2	is	be	AUX
cord-301856-71syce4n	227	3	just	just	ADV
cord-301856-71syce4n	227	4	the	the	DET
cord-301856-71syce4n	227	5	starting	starting	NOUN
cord-301856-71syce4n	227	6	point	point	NOUN
cord-301856-71syce4n	227	7	to	to	PART
cord-301856-71syce4n	227	8	unveil	unveil	VERB
cord-301856-71syce4n	227	9	the	the	DET
cord-301856-71syce4n	227	10	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	227	11	history	history	NOUN
cord-301856-71syce4n	227	12	of	of	ADP
cord-301856-71syce4n	227	13	the	the	DET
cord-301856-71syce4n	227	14	relationships	relationship	NOUN
cord-301856-71syce4n	227	15	between	between	ADP
cord-301856-71syce4n	227	16	pathogens	pathogen	NOUN
cord-301856-71syce4n	227	17	,	,	PUNCT
cord-301856-71syce4n	227	18	the	the	DET
cord-301856-71syce4n	227	19	immune	immune	ADJ
cord-301856-71syce4n	227	20	system	system	NOUN
cord-301856-71syce4n	227	21	,	,	PUNCT
cord-301856-71syce4n	227	22	and	and	CCONJ
cord-301856-71syce4n	227	23	humans	human	NOUN
cord-301856-71syce4n	227	24	.	.	PUNCT
cord-301856-71syce4n	228	1	further	further	ADJ
cord-301856-71syce4n	228	2	investigation	investigation	NOUN
cord-301856-71syce4n	228	3	of	of	ADP
cord-301856-71syce4n	228	4	the	the	DET
cord-301856-71syce4n	228	5	functional	functional	ADJ
cord-301856-71syce4n	228	6	adaptations	adaptation	NOUN
cord-301856-71syce4n	228	7	of	of	ADP
cord-301856-71syce4n	228	8	human	human	ADJ
cord-301856-71syce4n	228	9	populations	population	NOUN
cord-301856-71syce4n	228	10	is	be	AUX
cord-301856-71syce4n	228	11	warranted	warrant	VERB
cord-301856-71syce4n	228	12	to	to	PART
cord-301856-71syce4n	228	13	provide	provide	VERB
cord-301856-71syce4n	228	14	a	a	DET
cord-301856-71syce4n	228	15	broad	broad	ADJ
cord-301856-71syce4n	228	16	picture	picture	NOUN
cord-301856-71syce4n	228	17	of	of	ADP
cord-301856-71syce4n	228	18	the	the	DET
cord-301856-71syce4n	228	19	functional	functional	ADJ
cord-301856-71syce4n	228	20	consequences	consequence	NOUN
cord-301856-71syce4n	228	21	of	of	ADP
cord-301856-71syce4n	228	22	evolution	evolution	NOUN
cord-301856-71syce4n	228	23	in	in	ADP
cord-301856-71syce4n	228	24	human	human	ADJ
cord-301856-71syce4n	228	25	immunity	immunity	NOUN
cord-301856-71syce4n	228	26	.	.	PUNCT
cord-301856-71syce4n	229	1	acknowledgments	acknowledgment	VERB
cord-301856-71syce4n	229	2	m.g.n	m.g.n	X
cord-301856-71syce4n	229	3	.	.	PROPN
cord-301856-71syce4n	229	4	is	be	AUX
cord-301856-71syce4n	229	5	supported	support	VERB
cord-301856-71syce4n	229	6	by	by	ADP
cord-301856-71syce4n	229	7	a	a	DET
cord-301856-71syce4n	229	8	spinoza	spinoza	PROPN
cord-301856-71syce4n	229	9	grant	grant	NOUN
cord-301856-71syce4n	229	10	of	of	ADP
cord-301856-71syce4n	229	11	the	the	DET
cord-301856-71syce4n	229	12	netherlands	netherlands	PROPN
cord-301856-71syce4n	229	13	organization	organization	NOUN
cord-301856-71syce4n	229	14	for	for	ADP
cord-301856-71syce4n	229	15	scientific	scientific	ADJ
cord-301856-71syce4n	229	16	research	research	NOUN
cord-301856-71syce4n	229	17	and	and	CCONJ
cord-301856-71syce4n	229	18	an	an	DET
cord-301856-71syce4n	229	19	erc	erc	ADJ
cord-301856-71syce4n	229	20	advanced	advanced	ADJ
cord-301856-71syce4n	229	21	grant	grant	NOUN
cord-301856-71syce4n	229	22	(	(	PUNCT
cord-301856-71syce4n	229	23	#	#	SYM
cord-301856-71syce4n	229	24	833247	833247	NUM
cord-301856-71syce4n	229	25	)	)	PUNCT
cord-301856-71syce4n	229	26	.	.	PUNCT
cord-301856-71syce4n	230	1	the	the	DET
cord-301856-71syce4n	230	2	funders	funder	NOUN
cord-301856-71syce4n	230	3	had	have	VERB
cord-301856-71syce4n	230	4	no	no	DET
cord-301856-71syce4n	230	5	role	role	NOUN
cord-301856-71syce4n	230	6	in	in	ADP
cord-301856-71syce4n	230	7	study	study	NOUN
cord-301856-71syce4n	230	8	design	design	NOUN
cord-301856-71syce4n	230	9	,	,	PUNCT
cord-301856-71syce4n	230	10	data	datum	NOUN
cord-301856-71syce4n	230	11	collection	collection	NOUN
cord-301856-71syce4n	230	12	and	and	CCONJ
cord-301856-71syce4n	230	13	interpretation	interpretation	NOUN
cord-301856-71syce4n	230	14	,	,	PUNCT
cord-301856-71syce4n	230	15	or	or	CCONJ
cord-301856-71syce4n	230	16	the	the	DET
cord-301856-71syce4n	230	17	decision	decision	NOUN
cord-301856-71syce4n	230	18	to	to	PART
cord-301856-71syce4n	230	19	submit	submit	VERB
cord-301856-71syce4n	230	20	the	the	DET
cord-301856-71syce4n	230	21	work	work	NOUN
cord-301856-71syce4n	230	22	for	for	ADP
cord-301856-71syce4n	230	23	publication	publication	NOUN
cord-301856-71syce4n	230	24	.	.	PUNCT
cord-301856-71syce4n	231	1	we	we	PRON
cord-301856-71syce4n	231	2	thank	thank	VERB
cord-301856-71syce4n	231	3	laszlo	laszlo	PROPN
cord-301856-71syce4n	231	4	a.	a.	PROPN
cord-301856-71syce4n	231	5	groh	groh	PROPN
cord-301856-71syce4n	231	6	for	for	ADP
cord-301856-71syce4n	231	7	which	which	PRON
cord-301856-71syce4n	231	8	are	be	AUX
cord-301856-71syce4n	231	9	the	the	DET
cord-301856-71syce4n	231	10	strongest	strong	ADJ
cord-301856-71syce4n	231	11	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	231	12	forces	force	NOUN
cord-301856-71syce4n	231	13	that	that	PRON
cord-301856-71syce4n	231	14	drive	drive	VERB
cord-301856-71syce4n	231	15	the	the	DET
cord-301856-71syce4n	231	16	evolution	evolution	NOUN
cord-301856-71syce4n	231	17	of	of	ADP
cord-301856-71syce4n	231	18	the	the	DET
cord-301856-71syce4n	231	19	human	human	ADJ
cord-301856-71syce4n	231	20	innate	innate	ADJ
cord-301856-71syce4n	231	21	immune	immune	ADJ
cord-301856-71syce4n	231	22	system	system	NOUN
cord-301856-71syce4n	231	23	?	?	PUNCT
cord-301856-71syce4n	232	1	how	how	SCONJ
cord-301856-71syce4n	232	2	long	long	ADV
cord-301856-71syce4n	232	3	does	do	AUX
cord-301856-71syce4n	232	4	the	the	DET
cord-301856-71syce4n	232	5	genome	genome	NOUN
cord-301856-71syce4n	232	6	of	of	ADP
cord-301856-71syce4n	232	7	a	a	DET
cord-301856-71syce4n	232	8	given	give	VERB
cord-301856-71syce4n	232	9	population	population	NOUN
cord-301856-71syce4n	232	10	take	take	VERB
cord-301856-71syce4n	232	11	to	to	PART
cord-301856-71syce4n	232	12	adapt	adapt	VERB
cord-301856-71syce4n	232	13	to	to	ADP
cord-301856-71syce4n	232	14	a	a	DET
cord-301856-71syce4n	232	15	new	new	ADJ
cord-301856-71syce4n	232	16	infectious	infectious	ADJ
cord-301856-71syce4n	232	17	threat	threat	NOUN
cord-301856-71syce4n	232	18	?	?	PUNCT
cord-301856-71syce4n	233	1	are	be	AUX
cord-301856-71syce4n	233	2	the	the	DET
cord-301856-71syce4n	233	3	mechanisms	mechanism	NOUN
cord-301856-71syce4n	233	4	of	of	ADP
cord-301856-71syce4n	233	5	resistance	resistance	NOUN
cord-301856-71syce4n	233	6	to	to	ADP
cord-301856-71syce4n	233	7	infection	infection	NOUN
cord-301856-71syce4n	233	8	transmitted	transmit	VERB
cord-301856-71syce4n	233	9	only	only	ADV
cord-301856-71syce4n	233	10	via	via	ADP
cord-301856-71syce4n	233	11	genetic	genetic	ADJ
cord-301856-71syce4n	233	12	modifications	modification	NOUN
cord-301856-71syce4n	233	13	,	,	PUNCT
cord-301856-71syce4n	233	14	or	or	CCONJ
cord-301856-71syce4n	233	15	can	can	AUX
cord-301856-71syce4n	233	16	epigenetic	epigenetic	ADJ
cord-301856-71syce4n	233	17	adaptations	adaptation	NOUN
cord-301856-71syce4n	233	18	to	to	ADP
cord-301856-71syce4n	233	19	resistance	resistance	NOUN
cord-301856-71syce4n	233	20	also	also	ADV
cord-301856-71syce4n	233	21	be	be	AUX
cord-301856-71syce4n	233	22	transmitted	transmit	VERB
cord-301856-71syce4n	233	23	to	to	ADP
cord-301856-71syce4n	233	24	the	the	DET
cord-301856-71syce4n	233	25	progeny	progeny	NOUN
cord-301856-71syce4n	233	26	,	,	PUNCT
cord-301856-71syce4n	233	27	and	and	CCONJ
cord-301856-71syce4n	233	28	under	under	ADP
cord-301856-71syce4n	233	29	what	what	DET
cord-301856-71syce4n	233	30	circumstances	circumstance	NOUN
cord-301856-71syce4n	233	31	?	?	PUNCT
cord-301856-71syce4n	234	1	the	the	DET
cord-301856-71syce4n	234	2	development	development	NOUN
cord-301856-71syce4n	234	3	of	of	ADP
cord-301856-71syce4n	234	4	single	single	ADJ
cord-301856-71syce4n	234	5	-	-	PUNCT
cord-301856-71syce4n	234	6	cell	cell	NOUN
cord-301856-71syce4n	234	7	sequencing	sequence	VERB
cord-301856-71syce4n	234	8	technologies	technology	NOUN
cord-301856-71syce4n	234	9	has	have	AUX
cord-301856-71syce4n	234	10	opened	open	VERB
cord-301856-71syce4n	234	11	new	new	ADJ
cord-301856-71syce4n	234	12	fields	field	NOUN
cord-301856-71syce4n	234	13	of	of	ADP
cord-301856-71syce4n	234	14	study	study	NOUN
cord-301856-71syce4n	234	15	.	.	PUNCT
cord-301856-71syce4n	235	1	how	how	SCONJ
cord-301856-71syce4n	235	2	does	do	AUX
cord-301856-71syce4n	235	3	genetic	genetic	ADJ
cord-301856-71syce4n	235	4	variation	variation	NOUN
cord-301856-71syce4n	235	5	of	of	ADP
cord-301856-71syce4n	235	6	the	the	DET
cord-301856-71syce4n	235	7	expression	expression	NOUN
cord-301856-71syce4n	235	8	of	of	ADP
cord-301856-71syce4n	235	9	a	a	DET
cord-301856-71syce4n	235	10	specific	specific	ADJ
cord-301856-71syce4n	235	11	variant	variant	NOUN
cord-301856-71syce4n	235	12	vary	vary	VERB
cord-301856-71syce4n	235	13	between	between	ADP
cord-301856-71syce4n	235	14	different	different	ADJ
cord-301856-71syce4n	235	15	cell	cell	NOUN
cord-301856-71syce4n	235	16	subsets	subset	NOUN
cord-301856-71syce4n	235	17	and	and	CCONJ
cord-301856-71syce4n	235	18	how	how	SCONJ
cord-301856-71syce4n	235	19	does	do	AUX
cord-301856-71syce4n	235	20	it	it	PRON
cord-301856-71syce4n	235	21	affect	affect	VERB
cord-301856-71syce4n	235	22	the	the	DET
cord-301856-71syce4n	235	23	overall	overall	ADJ
cord-301856-71syce4n	235	24	phenotype	phenotype	NOUN
cord-301856-71syce4n	235	25	of	of	ADP
cord-301856-71syce4n	235	26	an	an	DET
cord-301856-71syce4n	235	27	individual	individual	NOUN
cord-301856-71syce4n	235	28	within	within	ADP
cord-301856-71syce4n	235	29	a	a	DET
cord-301856-71syce4n	235	30	population	population	NOUN
cord-301856-71syce4n	235	31	?	?	PUNCT
cord-301856-71syce4n	236	1	are	be	AUX
cord-301856-71syce4n	236	2	there	there	PRON
cord-301856-71syce4n	236	3	specific	specific	ADJ
cord-301856-71syce4n	236	4	immune	immune	ADJ
cord-301856-71syce4n	236	5	processes	process	NOUN
cord-301856-71syce4n	236	6	that	that	PRON
cord-301856-71syce4n	236	7	are	be	AUX
cord-301856-71syce4n	236	8	preferentially	preferentially	ADV
cord-301856-71syce4n	236	9	impacted	impact	VERB
cord-301856-71syce4n	236	10	by	by	ADP
cord-301856-71syce4n	236	11	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	236	12	pressures	pressure	NOUN
cord-301856-71syce4n	236	13	?	?	PUNCT
cord-301856-71syce4n	237	1	in	in	ADP
cord-301856-71syce4n	237	2	western	western	ADJ
cord-301856-71syce4n	237	3	societies	society	NOUN
cord-301856-71syce4n	237	4	we	we	PRON
cord-301856-71syce4n	237	5	enjoy	enjoy	VERB
cord-301856-71syce4n	237	6	a	a	DET
cord-301856-71syce4n	237	7	life	life	NOUN
cord-301856-71syce4n	237	8	expectancy	expectancy	NOUN
cord-301856-71syce4n	237	9	vastly	vastly	ADV
cord-301856-71syce4n	237	10	superior	superior	ADJ
cord-301856-71syce4n	237	11	to	to	ADP
cord-301856-71syce4n	237	12	that	that	PRON
cord-301856-71syce4n	237	13	of	of	ADP
cord-301856-71syce4n	237	14	our	our	PRON
cord-301856-71syce4n	237	15	predecessors	predecessor	NOUN
cord-301856-71syce4n	237	16	,	,	PUNCT
cord-301856-71syce4n	237	17	but	but	CCONJ
cord-301856-71syce4n	237	18	at	at	ADP
cord-301856-71syce4n	237	19	the	the	DET
cord-301856-71syce4n	237	20	same	same	ADJ
cord-301856-71syce4n	237	21	time	time	NOUN
cord-301856-71syce4n	237	22	,	,	PUNCT
cord-301856-71syce4n	237	23	we	we	PRON
cord-301856-71syce4n	237	24	suffer	suffer	VERB
cord-301856-71syce4n	237	25	diseases	disease	NOUN
cord-301856-71syce4n	237	26	that	that	SCONJ
cord-301856-71syce4n	237	27	they	they	PRON
cord-301856-71syce4n	237	28	did	do	AUX
cord-301856-71syce4n	237	29	not	not	PART
cord-301856-71syce4n	237	30	suffer	suffer	VERB
cord-301856-71syce4n	237	31	.	.	PUNCT
cord-301856-71syce4n	238	1	can	can	AUX
cord-301856-71syce4n	238	2	some	some	PRON
cord-301856-71syce4n	238	3	of	of	ADP
cord-301856-71syce4n	238	4	the	the	DET
cord-301856-71syce4n	238	5	reasons	reason	NOUN
cord-301856-71syce4n	238	6	for	for	ADP
cord-301856-71syce4n	238	7	these	these	DET
cord-301856-71syce4n	238	8	changes	change	NOUN
cord-301856-71syce4n	238	9	lie	lie	VERB
cord-301856-71syce4n	238	10	among	among	ADP
cord-301856-71syce4n	238	11	some	some	PRON
cord-301856-71syce4n	238	12	of	of	ADP
cord-301856-71syce4n	238	13	those	those	DET
cord-301856-71syce4n	238	14	bacteria	bacteria	NOUN
cord-301856-71syce4n	238	15	that	that	PRON
cord-301856-71syce4n	238	16	we	we	PRON
cord-301856-71syce4n	238	17	have	have	AUX
cord-301856-71syce4n	238	18	somehow	somehow	ADV
cord-301856-71syce4n	238	19	lost	lose	VERB
cord-301856-71syce4n	238	20	in	in	ADP
cord-301856-71syce4n	238	21	our	our	PRON
cord-301856-71syce4n	238	22	microbiome	microbiome	NOUN
cord-301856-71syce4n	238	23	?	?	PUNCT
cord-301856-71syce4n	239	1	identifying	identify	VERB
cord-301856-71syce4n	239	2	these	these	DET
cord-301856-71syce4n	239	3	bacteria	bacteria	NOUN
cord-301856-71syce4n	239	4	and	and	CCONJ
cord-301856-71syce4n	239	5	understanding	understand	VERB
cord-301856-71syce4n	239	6	their	their	PRON
cord-301856-71syce4n	239	7	effects	effect	NOUN
cord-301856-71syce4n	239	8	on	on	ADP
cord-301856-71syce4n	239	9	the	the	DET
cord-301856-71syce4n	239	10	human	human	ADJ
cord-301856-71syce4n	239	11	body	body	NOUN
cord-301856-71syce4n	239	12	might	might	AUX
cord-301856-71syce4n	239	13	be	be	AUX
cord-301856-71syce4n	239	14	the	the	DET
cord-301856-71syce4n	239	15	first	first	ADJ
cord-301856-71syce4n	239	16	step	step	NOUN
cord-301856-71syce4n	239	17	to	to	ADP
cord-301856-71syce4n	239	18	developing	develop	VERB
cord-301856-71syce4n	239	19	putative	putative	ADJ
cord-301856-71syce4n	239	20	therapies	therapy	NOUN
cord-301856-71syce4n	239	21	based	base	VERB
cord-301856-71syce4n	239	22	on	on	ADP
cord-301856-71syce4n	239	23	bacterial	bacterial	ADJ
cord-301856-71syce4n	239	24	restoration	restoration	NOUN
cord-301856-71syce4n	239	25	.	.	PUNCT
cord-301856-71syce4n	240	1	since	since	SCONJ
cord-301856-71syce4n	240	2	many	many	ADJ
cord-301856-71syce4n	240	3	of	of	ADP
cord-301856-71syce4n	240	4	the	the	DET
cord-301856-71syce4n	240	5	variants	variant	NOUN
cord-301856-71syce4n	240	6	causing	cause	VERB
cord-301856-71syce4n	240	7	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	240	8	diseases	disease	NOUN
cord-301856-71syce4n	240	9	are	be	AUX
cord-301856-71syce4n	240	10	linked	link	VERB
cord-301856-71syce4n	240	11	to	to	ADP
cord-301856-71syce4n	240	12	an	an	DET
cord-301856-71syce4n	240	13	enhanced	enhanced	ADJ
cord-301856-71syce4n	240	14	responsiveness	responsiveness	NOUN
cord-301856-71syce4n	240	15	to	to	ADP
cord-301856-71syce4n	240	16	pathogens	pathogen	NOUN
cord-301856-71syce4n	240	17	that	that	PRON
cord-301856-71syce4n	240	18	is	be	AUX
cord-301856-71syce4n	240	19	no	no	ADV
cord-301856-71syce4n	240	20	longer	long	ADV
cord-301856-71syce4n	240	21	needed	need	VERB
cord-301856-71syce4n	240	22	in	in	ADP
cord-301856-71syce4n	240	23	developed	develop	VERB
cord-301856-71syce4n	240	24	countries	country	NOUN
cord-301856-71syce4n	240	25	,	,	PUNCT
cord-301856-71syce4n	240	26	could	could	AUX
cord-301856-71syce4n	240	27	these	these	DET
cord-301856-71syce4n	240	28	genes	gene	NOUN
cord-301856-71syce4n	240	29	and	and	CCONJ
cord-301856-71syce4n	240	30	their	their	PRON
cord-301856-71syce4n	240	31	related	relate	VERB
cord-301856-71syce4n	240	32	pathways	pathway	NOUN
cord-301856-71syce4n	240	33	be	be	AUX
cord-301856-71syce4n	240	34	employed	employ	VERB
cord-301856-71syce4n	240	35	as	as	ADP
cord-301856-71syce4n	240	36	targets	target	NOUN
cord-301856-71syce4n	240	37	for	for	ADP
cord-301856-71syce4n	240	38	new	new	ADJ
cord-301856-71syce4n	240	39	putative	putative	ADJ
cord-301856-71syce4n	240	40	therapeutic	therapeutic	ADJ
cord-301856-71syce4n	240	41	approaches	approach	NOUN
cord-301856-71syce4n	240	42	against	against	ADP
cord-301856-71syce4n	240	43	inflammatory/	inflammatory/	ADJ
cord-301856-71syce4n	240	44	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	240	45	syndromes	syndrome	NOUN
cord-301856-71syce4n	240	46	?	?	PUNCT
cord-301856-71syce4n	241	1	are	be	AUX
cord-301856-71syce4n	241	2	other	other	ADJ
cord-301856-71syce4n	241	3	newly	newly	ADV
cord-301856-71syce4n	241	4	described	describe	VERB
cord-301856-71syce4n	241	5	genetic	genetic	ADJ
cord-301856-71syce4n	241	6	regulatory	regulatory	ADJ
cord-301856-71syce4n	241	7	pathways	pathway	NOUN
cord-301856-71syce4n	241	8	,	,	PUNCT
cord-301856-71syce4n	241	9	such	such	ADJ
cord-301856-71syce4n	241	10	as	as	ADP
cord-301856-71syce4n	241	11	interfering	interfere	VERB
cord-301856-71syce4n	241	12	rna	rna	NOUN
cord-301856-71syce4n	241	13	or	or	CCONJ
cord-301856-71syce4n	241	14	long	long	ADJ
cord-301856-71syce4n	241	15	noncoding	noncode	VERB
cord-301856-71syce4n	241	16	rnas	rna	NOUN
cord-301856-71syce4n	241	17	,	,	PUNCT
cord-301856-71syce4n	241	18	also	also	ADV
cord-301856-71syce4n	241	19	influenced	influence	VERB
cord-301856-71syce4n	241	20	by	by	ADP
cord-301856-71syce4n	241	21	pathogen	pathogen	PROPN
cord-301856-71syce4n	241	22	-	-	PUNCT
cord-301856-71syce4n	241	23	driven	drive	VERB
cord-301856-71syce4n	241	24	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	241	25	processes	process	NOUN
cord-301856-71syce4n	241	26	in	in	ADP
cord-301856-71syce4n	241	27	different	different	ADJ
cord-301856-71syce4n	241	28	populations	population	NOUN
cord-301856-71syce4n	241	29	globally	globally	ADV
cord-301856-71syce4n	241	30	?	?	PUNCT
cord-301856-71syce4n	242	1	proofreading	proofreading	NOUN
cord-301856-71syce4n	242	2	and	and	CCONJ
cord-301856-71syce4n	242	3	correction	correction	NOUN
cord-301856-71syce4n	242	4	of	of	ADP
cord-301856-71syce4n	242	5	the	the	DET
cord-301856-71syce4n	242	6	manuscript	manuscript	NOUN
cord-301856-71syce4n	242	7	.	.	PUNCT
cord-301856-71syce4n	243	1	we	we	PRON
cord-301856-71syce4n	243	2	additionally	additionally	ADV
cord-301856-71syce4n	243	3	thank	thank	VERB
cord-301856-71syce4n	243	4	srinivas	srinivas	PROPN
cord-301856-71syce4n	243	5	agra	agra	PROPN
cord-301856-71syce4n	243	6	for	for	ADP
cord-301856-71syce4n	243	7	providing	provide	VERB
cord-301856-71syce4n	243	8	the	the	DET
cord-301856-71syce4n	243	9	figure	figure	NOUN
cord-301856-71syce4n	243	10	icon	icon	NOUN
cord-301856-71syce4n	243	11	'	'	PUNCT
cord-301856-71syce4n	243	12	bacteria	bacteria	NOUN
cord-301856-71syce4n	243	13	'	'	PUNCT
cord-301856-71syce4n	243	14	as	as	ADV
cord-301856-71syce4n	243	15	deposited	deposit	VERB
cord-301856-71syce4n	243	16	on	on	ADP
cord-301856-71syce4n	243	17	https://thenounproject.com	https://thenounproject.com	PROPN
cord-301856-71syce4n	243	18	.	.	PUNCT
cord-301856-71syce4n	244	1	natural	natural	ADJ
cord-301856-71syce4n	244	2	selection	selection	NOUN
cord-301856-71syce4n	244	3	and	and	CCONJ
cord-301856-71syce4n	244	4	infectious	infectious	ADJ
cord-301856-71syce4n	244	5	disease	disease	NOUN
cord-301856-71syce4n	244	6	in	in	ADP
cord-301856-71syce4n	244	7	human	human	ADJ
cord-301856-71syce4n	244	8	populations	population	NOUN
cord-301856-71syce4n	244	9	genomic	genomic	ADJ
cord-301856-71syce4n	244	10	signatures	signature	NOUN
cord-301856-71syce4n	244	11	of	of	ADP
cord-301856-71syce4n	244	12	selective	selective	ADJ
cord-301856-71syce4n	244	13	pressures	pressure	NOUN
cord-301856-71syce4n	244	14	and	and	CCONJ
cord-301856-71syce4n	244	15	introgression	introgression	NOUN
cord-301856-71syce4n	244	16	from	from	ADP
cord-301856-71syce4n	244	17	archaic	archaic	ADJ
cord-301856-71syce4n	244	18	hominins	hominin	NOUN
cord-301856-71syce4n	244	19	at	at	ADP
cord-301856-71syce4n	244	20	human	human	ADJ
cord-301856-71syce4n	244	21	innate	innate	ADJ
cord-301856-71syce4n	244	22	immunity	immunity	NOUN
cord-301856-71syce4n	244	23	genes	gene	NOUN
cord-301856-71syce4n	244	24	genome	genome	NOUN
cord-301856-71syce4n	244	25	-	-	PUNCT
cord-301856-71syce4n	244	26	wide	wide	ADJ
cord-301856-71syce4n	244	27	identification	identification	NOUN
cord-301856-71syce4n	244	28	of	of	ADP
cord-301856-71syce4n	244	29	regulatory	regulatory	ADJ
cord-301856-71syce4n	244	30	sequences	sequence	NOUN
cord-301856-71syce4n	244	31	undergoing	undergo	VERB
cord-301856-71syce4n	244	32	accelerated	accelerate	VERB
cord-301856-71syce4n	244	33	evolution	evolution	NOUN
cord-301856-71syce4n	244	34	in	in	ADP
cord-301856-71syce4n	244	35	the	the	DET
cord-301856-71syce4n	244	36	human	human	ADJ
cord-301856-71syce4n	244	37	genome	genome	NOUN
cord-301856-71syce4n	244	38	divergent	divergent	ADJ
cord-301856-71syce4n	244	39	selection	selection	NOUN
cord-301856-71syce4n	244	40	of	of	ADP
cord-301856-71syce4n	244	41	pattern	pattern	NOUN
cord-301856-71syce4n	244	42	recognition	recognition	NOUN
cord-301856-71syce4n	244	43	receptors	receptor	NOUN
cord-301856-71syce4n	244	44	in	in	ADP
cord-301856-71syce4n	244	45	mammals	mammal	NOUN
cord-301856-71syce4n	244	46	with	with	ADP
cord-301856-71syce4n	244	47	different	different	ADJ
cord-301856-71syce4n	244	48	ecological	ecological	ADJ
cord-301856-71syce4n	244	49	characteristics	characteristic	NOUN
cord-301856-71syce4n	244	50	a	a	DET
cord-301856-71syce4n	244	51	population	population	NOUN
cord-301856-71syce4n	244	52	genetic	genetic	ADJ
cord-301856-71syce4n	244	53	interpretation	interpretation	NOUN
cord-301856-71syce4n	244	54	of	of	ADP
cord-301856-71syce4n	244	55	gwas	gwas	PROPN
cord-301856-71syce4n	244	56	findings	finding	NOUN
cord-301856-71syce4n	244	57	for	for	ADP
cord-301856-71syce4n	244	58	human	human	ADJ
cord-301856-71syce4n	244	59	quantitative	quantitative	ADJ
cord-301856-71syce4n	244	60	traits	trait	NOUN
cord-301856-71syce4n	244	61	new	new	ADJ
cord-301856-71syce4n	244	62	fossils	fossil	NOUN
cord-301856-71syce4n	244	63	from	from	ADP
cord-301856-71syce4n	244	64	jebel	jebel	PROPN
cord-301856-71syce4n	244	65	irhoud	irhoud	PROPN
cord-301856-71syce4n	244	66	,	,	PUNCT
cord-301856-71syce4n	244	67	morocco	morocco	PROPN
cord-301856-71syce4n	244	68	and	and	CCONJ
cord-301856-71syce4n	244	69	the	the	DET
cord-301856-71syce4n	244	70	pan	pan	ADJ
cord-301856-71syce4n	244	71	-	-	ADJ
cord-301856-71syce4n	244	72	african	african	ADJ
cord-301856-71syce4n	244	73	origin	origin	NOUN
cord-301856-71syce4n	244	74	of	of	ADP
cord-301856-71syce4n	244	75	homo	homo	PROPN
cord-301856-71syce4n	244	76	sapiens	sapiens	PROPN
cord-301856-71syce4n	244	77	protection	protection	PROPN
cord-301856-71syce4n	244	78	afforded	afford	VERB
cord-301856-71syce4n	244	79	by	by	ADP
cord-301856-71syce4n	244	80	sicklecell	sicklecell	PROPN
cord-301856-71syce4n	244	81	trait	trait	NOUN
cord-301856-71syce4n	244	82	against	against	ADP
cord-301856-71syce4n	244	83	subtertian	subtertian	ADJ
cord-301856-71syce4n	244	84	malareal	malareal	ADJ
cord-301856-71syce4n	244	85	infection	infection	NOUN
cord-301856-71syce4n	244	86	extended	extend	VERB
cord-301856-71syce4n	244	87	linkage	linkage	NOUN
cord-301856-71syce4n	244	88	disequilibrium	disequilibrium	NOUN
cord-301856-71syce4n	244	89	surrounding	surround	VERB
cord-301856-71syce4n	244	90	the	the	DET
cord-301856-71syce4n	244	91	hemoglobin	hemoglobin	NOUN
cord-301856-71syce4n	244	92	e	e	NOUN
cord-301856-71syce4n	244	93	variant	variant	NOUN
cord-301856-71syce4n	244	94	due	due	ADP
cord-301856-71syce4n	244	95	to	to	ADP
cord-301856-71syce4n	244	96	malarial	malarial	ADJ
cord-301856-71syce4n	244	97	selection	selection	NOUN
cord-301856-71syce4n	244	98	haemoglobin	haemoglobin	NOUN
cord-301856-71syce4n	244	99	c	c	PROPN
cord-301856-71syce4n	244	100	protects	protect	VERB
cord-301856-71syce4n	244	101	against	against	ADP
cord-301856-71syce4n	244	102	clinical	clinical	ADJ
cord-301856-71syce4n	244	103	plasmodium	plasmodium	NOUN
cord-301856-71syce4n	244	104	falciparum	falciparum	NOUN
cord-301856-71syce4n	244	105	malaria	malaria	NOUN
cord-301856-71syce4n	244	106	positive	positive	ADJ
cord-301856-71syce4n	244	107	natural	natural	ADJ
cord-301856-71syce4n	244	108	selection	selection	NOUN
cord-301856-71syce4n	244	109	in	in	ADP
cord-301856-71syce4n	244	110	the	the	DET
cord-301856-71syce4n	244	111	human	human	ADJ
cord-301856-71syce4n	244	112	lineage	lineage	NOUN
cord-301856-71syce4n	244	113	genetic	genetic	PROPN
cord-301856-71syce4n	244	114	ancestry	ancestry	NOUN
cord-301856-71syce4n	244	115	and	and	CCONJ
cord-301856-71syce4n	244	116	population	population	NOUN
cord-301856-71syce4n	244	117	differences	difference	NOUN
cord-301856-71syce4n	244	118	in	in	ADP
cord-301856-71syce4n	244	119	levels	level	NOUN
cord-301856-71syce4n	244	120	of	of	ADP
cord-301856-71syce4n	244	121	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	244	122	cytokines	cytokine	NOUN
cord-301856-71syce4n	244	123	in	in	ADP
cord-301856-71syce4n	244	124	women	woman	NOUN
cord-301856-71syce4n	244	125	:	:	PUNCT
cord-301856-71syce4n	244	126	role	role	NOUN
cord-301856-71syce4n	244	127	for	for	ADP
cord-301856-71syce4n	244	128	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	244	129	selection	selection	NOUN
cord-301856-71syce4n	244	130	and	and	CCONJ
cord-301856-71syce4n	244	131	environmental	environmental	ADJ
cord-301856-71syce4n	244	132	factors	factor	NOUN
cord-301856-71syce4n	244	133	world	world	NOUN
cord-301856-71syce4n	244	134	distribution	distribution	NOUN
cord-301856-71syce4n	244	135	,	,	PUNCT
cord-301856-71syce4n	244	136	population	population	NOUN
cord-301856-71syce4n	244	137	genetics	genetic	NOUN
cord-301856-71syce4n	244	138	,	,	PUNCT
cord-301856-71syce4n	244	139	and	and	CCONJ
cord-301856-71syce4n	244	140	health	health	NOUN
cord-301856-71syce4n	244	141	burden	burden	NOUN
cord-301856-71syce4n	244	142	of	of	ADP
cord-301856-71syce4n	244	143	the	the	DET
cord-301856-71syce4n	244	144	hemoglobinopathies	hemoglobinopathy	NOUN
cord-301856-71syce4n	244	145	.	.	PUNCT
cord-301856-71syce4n	245	1	cold	cold	ADJ
cord-301856-71syce4n	245	2	spring	spring	PROPN
cord-301856-71syce4n	245	3	harb	harb	PROPN
cord-301856-71syce4n	245	4	caspase-12	caspase-12	PUNCT
cord-301856-71syce4n	245	5	dampens	dampen	VERB
cord-301856-71syce4n	245	6	the	the	DET
cord-301856-71syce4n	245	7	immune	immune	ADJ
cord-301856-71syce4n	245	8	response	response	NOUN
cord-301856-71syce4n	245	9	to	to	ADP
cord-301856-71syce4n	245	10	malaria	malaria	NOUN
cord-301856-71syce4n	245	11	independently	independently	ADV
cord-301856-71syce4n	245	12	of	of	ADP
cord-301856-71syce4n	245	13	the	the	DET
cord-301856-71syce4n	245	14	inflammasome	inflammasome	NOUN
cord-301856-71syce4n	245	15	by	by	ADP
cord-301856-71syce4n	245	16	targeting	target	VERB
cord-301856-71syce4n	245	17	nf	nf	PROPN
cord-301856-71syce4n	245	18	-	-	PUNCT
cord-301856-71syce4n	245	19	b	b	NOUN
cord-301856-71syce4n	245	20	signaling	signaling	NOUN
cord-301856-71syce4n	245	21	does	do	AUX
cord-301856-71syce4n	245	22	caspase-12	caspase-12	PUNCT
cord-301856-71syce4n	245	23	suppress	suppress	VERB
cord-301856-71syce4n	245	24	inflammasome	inflammasome	NOUN
cord-301856-71syce4n	245	25	activation	activation	NOUN
cord-301856-71syce4n	245	26	?	?	PUNCT
cord-301856-71syce4n	246	1	first	first	ADV
cord-301856-71syce4n	246	2	homo	homo	ADJ
cord-301856-71syce4n	246	3	erectus	erectus	NOUN
cord-301856-71syce4n	246	4	from	from	ADP
cord-301856-71syce4n	246	5	turkey	turkey	NOUN
cord-301856-71syce4n	246	6	and	and	CCONJ
cord-301856-71syce4n	246	7	implications	implication	NOUN
cord-301856-71syce4n	246	8	for	for	ADP
cord-301856-71syce4n	246	9	migrations	migration	NOUN
cord-301856-71syce4n	246	10	into	into	ADP
cord-301856-71syce4n	246	11	temperate	temperate	NOUN
cord-301856-71syce4n	246	12	eurasia	eurasia	PROPN
cord-301856-71syce4n	246	13	genetics	genetics	PROPN
cord-301856-71syce4n	246	14	of	of	ADP
cord-301856-71syce4n	246	15	sub	sub	ADJ
cord-301856-71syce4n	246	16	-	-	ADJ
cord-301856-71syce4n	246	17	saharan	saharan	ADJ
cord-301856-71syce4n	246	18	african	african	ADJ
cord-301856-71syce4n	246	19	human	human	ADJ
cord-301856-71syce4n	246	20	population	population	NOUN
cord-301856-71syce4n	246	21	:	:	PUNCT
cord-301856-71syce4n	246	22	implications	implication	NOUN
cord-301856-71syce4n	246	23	for	for	ADP
cord-301856-71syce4n	246	24	hiv	hiv	PROPN
cord-301856-71syce4n	246	25	/	/	SYM
cord-301856-71syce4n	246	26	aids	aid	NOUN
cord-301856-71syce4n	246	27	,	,	PUNCT
cord-301856-71syce4n	246	28	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	246	29	,	,	PUNCT
cord-301856-71syce4n	246	30	and	and	CCONJ
cord-301856-71syce4n	246	31	malaria	malaria	VERB
cord-301856-71syce4n	246	32	the	the	DET
cord-301856-71syce4n	246	33	role	role	NOUN
cord-301856-71syce4n	246	34	of	of	ADP
cord-301856-71syce4n	246	35	ancestry	ancestry	NOUN
cord-301856-71syce4n	246	36	in	in	ADP
cord-301856-71syce4n	246	37	tb	tb	PROPN
cord-301856-71syce4n	246	38	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	246	39	of	of	ADP
cord-301856-71syce4n	246	40	an	an	DET
cord-301856-71syce4n	246	41	admixed	admixed	ADJ
cord-301856-71syce4n	246	42	south	south	ADJ
cord-301856-71syce4n	246	43	african	african	ADJ
cord-301856-71syce4n	246	44	population	population	PROPN
cord-301856-71syce4n	246	45	association	association	PROPN
cord-301856-71syce4n	246	46	of	of	ADP
cord-301856-71syce4n	246	47	the	the	DET
cord-301856-71syce4n	246	48	tlr1	tlr1	PROPN
cord-301856-71syce4n	246	49	variant	variant	NOUN
cord-301856-71syce4n	246	50	rs5743557	rs5743557	VERB
cord-301856-71syce4n	246	51	with	with	ADP
cord-301856-71syce4n	246	52	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	246	53	to	to	ADP
cord-301856-71syce4n	246	54	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	246	55	genome	genome	NOUN
cord-301856-71syce4n	246	56	-	-	PUNCT
cord-301856-71syce4n	246	57	wide	wide	ADJ
cord-301856-71syce4n	246	58	scans	scan	NOUN
cord-301856-71syce4n	246	59	provide	provide	VERB
cord-301856-71syce4n	246	60	evidence	evidence	NOUN
cord-301856-71syce4n	246	61	for	for	ADP
cord-301856-71syce4n	246	62	positive	positive	ADJ
cord-301856-71syce4n	246	63	selection	selection	NOUN
cord-301856-71syce4n	246	64	of	of	ADP
cord-301856-71syce4n	246	65	genes	gene	NOUN
cord-301856-71syce4n	246	66	implicated	implicate	VERB
cord-301856-71syce4n	246	67	in	in	ADP
cord-301856-71syce4n	246	68	lassa	lassa	ADJ
cord-301856-71syce4n	246	69	fever	fever	NOUN
cord-301856-71syce4n	246	70	the	the	DET
cord-301856-71syce4n	246	71	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	246	72	history	history	NOUN
cord-301856-71syce4n	246	73	of	of	ADP
cord-301856-71syce4n	246	74	the	the	DET
cord-301856-71syce4n	246	75	human	human	ADJ
cord-301856-71syce4n	246	76	face	face	NOUN
cord-301856-71syce4n	246	77	human	human	ADJ
cord-301856-71syce4n	246	78	occupation	occupation	NOUN
cord-301856-71syce4n	246	79	of	of	ADP
cord-301856-71syce4n	246	80	northern	northern	PROPN
cord-301856-71syce4n	246	81	australia	australia	PROPN
cord-301856-71syce4n	246	82	by	by	ADP
cord-301856-71syce4n	246	83	65,000	65,000	NUM
cord-301856-71syce4n	246	84	years	year	NOUN
cord-301856-71syce4n	246	85	ago	ago	ADV
cord-301856-71syce4n	246	86	the	the	DET
cord-301856-71syce4n	246	87	complete	complete	ADJ
cord-301856-71syce4n	246	88	genome	genome	NOUN
cord-301856-71syce4n	246	89	sequence	sequence	NOUN
cord-301856-71syce4n	246	90	of	of	ADP
cord-301856-71syce4n	246	91	a	a	DET
cord-301856-71syce4n	246	92	neanderthal	neanderthal	NOUN
cord-301856-71syce4n	246	93	from	from	ADP
cord-301856-71syce4n	246	94	the	the	DET
cord-301856-71syce4n	246	95	altai	altai	PROPN
cord-301856-71syce4n	246	96	mountains	mountains	PROPN
cord-301856-71syce4n	246	97	variation	variation	NOUN
cord-301856-71syce4n	246	98	and	and	CCONJ
cord-301856-71syce4n	246	99	functional	functional	ADJ
cord-301856-71syce4n	246	100	impact	impact	NOUN
cord-301856-71syce4n	246	101	of	of	ADP
cord-301856-71syce4n	246	102	neanderthal	neanderthal	PROPN
cord-301856-71syce4n	246	103	ancestry	ancestry	NOUN
cord-301856-71syce4n	246	104	in	in	ADP
cord-301856-71syce4n	246	105	western	western	PROPN
cord-301856-71syce4n	246	106	asia	asia	PROPN
cord-301856-71syce4n	246	107	disentangling	disentangle	VERB
cord-301856-71syce4n	246	108	immediate	immediate	ADJ
cord-301856-71syce4n	246	109	adaptive	adaptive	ADJ
cord-301856-71syce4n	246	110	introgression	introgression	NOUN
cord-301856-71syce4n	246	111	from	from	ADP
cord-301856-71syce4n	246	112	selection	selection	NOUN
cord-301856-71syce4n	246	113	on	on	ADP
cord-301856-71syce4n	246	114	standing	stand	VERB
cord-301856-71syce4n	246	115	introgressed	introgresse	VERB
cord-301856-71syce4n	246	116	variation	variation	NOUN
cord-301856-71syce4n	246	117	in	in	ADP
cord-301856-71syce4n	246	118	humans	human	NOUN
cord-301856-71syce4n	246	119	introgression	introgression	NOUN
cord-301856-71syce4n	246	120	of	of	ADP
cord-301856-71syce4n	246	121	neandertal	neandertal	ADJ
cord-301856-71syce4n	246	122	-	-	PUNCT
cord-301856-71syce4n	246	123	and	and	CCONJ
cord-301856-71syce4n	246	124	denisovan	denisovan	PROPN
cord-301856-71syce4n	246	125	-	-	PUNCT
cord-301856-71syce4n	246	126	like	like	ADJ
cord-301856-71syce4n	246	127	haplotypes	haplotype	NOUN
cord-301856-71syce4n	246	128	contributes	contribute	VERB
cord-301856-71syce4n	246	129	to	to	ADP
cord-301856-71syce4n	246	130	adaptive	adaptive	ADJ
cord-301856-71syce4n	246	131	variation	variation	NOUN
cord-301856-71syce4n	246	132	in	in	ADP
cord-301856-71syce4n	246	133	human	human	ADJ
cord-301856-71syce4n	246	134	toll	toll	NOUN
cord-301856-71syce4n	246	135	-	-	PUNCT
cord-301856-71syce4n	246	136	like	like	ADJ
cord-301856-71syce4n	246	137	receptors	receptor	NOUN
cord-301856-71syce4n	246	138	the	the	DET
cord-301856-71syce4n	246	139	shaping	shaping	NOUN
cord-301856-71syce4n	246	140	of	of	ADP
cord-301856-71syce4n	246	141	modern	modern	ADJ
cord-301856-71syce4n	246	142	human	human	ADJ
cord-301856-71syce4n	246	143	immune	immune	ADJ
cord-301856-71syce4n	246	144	systems	system	NOUN
cord-301856-71syce4n	246	145	by	by	ADP
cord-301856-71syce4n	246	146	multiregional	multiregional	ADJ
cord-301856-71syce4n	246	147	admixture	admixture	NOUN
cord-301856-71syce4n	246	148	with	with	ADP
cord-301856-71syce4n	246	149	archaic	archaic	ADJ
cord-301856-71syce4n	246	150	humans	human	NOUN
cord-301856-71syce4n	246	151	tlr10	tlr10	PROPN
cord-301856-71syce4n	246	152	senses	sense	VERB
cord-301856-71syce4n	246	153	hiv-1	hiv-1	PUNCT
cord-301856-71syce4n	246	154	proteins	protein	NOUN
cord-301856-71syce4n	246	155	and	and	CCONJ
cord-301856-71syce4n	246	156	significantly	significantly	ADV
cord-301856-71syce4n	246	157	enhances	enhance	VERB
cord-301856-71syce4n	246	158	hiv-1	hiv-1	PUNCT
cord-301856-71syce4n	246	159	infection	infection	NOUN
cord-301856-71syce4n	246	160	the	the	DET
cord-301856-71syce4n	246	161	role	role	NOUN
cord-301856-71syce4n	246	162	of	of	ADP
cord-301856-71syce4n	246	163	tlr2	tlr2	PROPN
cord-301856-71syce4n	246	164	in	in	ADP
cord-301856-71syce4n	246	165	infection	infection	NOUN
cord-301856-71syce4n	246	166	and	and	CCONJ
cord-301856-71syce4n	246	167	immunity	immunity	NOUN
cord-301856-71syce4n	246	168	variation	variation	NOUN
cord-301856-71syce4n	246	169	in	in	ADP
cord-301856-71syce4n	246	170	the	the	DET
cord-301856-71syce4n	246	171	tlr10/	tlr10/	PROPN
cord-301856-71syce4n	246	172	tlr1	tlr1	PROPN
cord-301856-71syce4n	246	173	/	/	SYM
cord-301856-71syce4n	246	174	tlr6	tlr6	PROPN
cord-301856-71syce4n	246	175	locus	locus	PROPN
cord-301856-71syce4n	246	176	is	be	AUX
cord-301856-71syce4n	246	177	the	the	DET
cord-301856-71syce4n	246	178	major	major	ADJ
cord-301856-71syce4n	246	179	genetic	genetic	ADJ
cord-301856-71syce4n	246	180	determinant	determinant	NOUN
cord-301856-71syce4n	246	181	of	of	ADP
cord-301856-71syce4n	246	182	interindividual	interindividual	ADJ
cord-301856-71syce4n	246	183	difference	difference	NOUN
cord-301856-71syce4n	246	184	in	in	ADP
cord-301856-71syce4n	246	185	tlr1/2	tlr1/2	ADV
cord-301856-71syce4n	246	186	-	-	PUNCT
cord-301856-71syce4n	246	187	mediated	mediate	VERB
cord-301856-71syce4n	246	188	responses	response	NOUN
cord-301856-71syce4n	246	189	race	race	NOUN
cord-301856-71syce4n	246	190	is	be	AUX
cord-301856-71syce4n	246	191	associated	associate	VERB
cord-301856-71syce4n	246	192	with	with	ADP
cord-301856-71syce4n	246	193	differences	difference	NOUN
cord-301856-71syce4n	246	194	in	in	ADP
cord-301856-71syce4n	246	195	airway	airway	NOUN
cord-301856-71syce4n	246	196	inflammation	inflammation	NOUN
cord-301856-71syce4n	246	197	in	in	ADP
cord-301856-71syce4n	246	198	patients	patient	NOUN
cord-301856-71syce4n	246	199	with	with	ADP
cord-301856-71syce4n	246	200	asthma	asthma	NOUN
cord-301856-71syce4n	246	201	genetic	genetic	ADJ
cord-301856-71syce4n	246	202	ancestry	ancestry	NOUN
cord-301856-71syce4n	246	203	and	and	CCONJ
cord-301856-71syce4n	246	204	natural	natural	ADJ
cord-301856-71syce4n	246	205	selection	selection	NOUN
cord-301856-71syce4n	246	206	drive	drive	NOUN
cord-301856-71syce4n	246	207	population	population	NOUN
cord-301856-71syce4n	246	208	differences	difference	NOUN
cord-301856-71syce4n	246	209	in	in	ADP
cord-301856-71syce4n	246	210	immune	immune	ADJ
cord-301856-71syce4n	246	211	responses	response	NOUN
cord-301856-71syce4n	246	212	to	to	ADP
cord-301856-71syce4n	246	213	pathogens	pathogen	NOUN
cord-301856-71syce4n	246	214	genetic	genetic	ADJ
cord-301856-71syce4n	246	215	adaptation	adaptation	NOUN
cord-301856-71syce4n	246	216	and	and	CCONJ
cord-301856-71syce4n	246	217	neandertal	neandertal	ADJ
cord-301856-71syce4n	246	218	admixture	admixture	NOUN
cord-301856-71syce4n	246	219	shaped	shape	VERB
cord-301856-71syce4n	246	220	the	the	DET
cord-301856-71syce4n	246	221	immune	immune	ADJ
cord-301856-71syce4n	246	222	system	system	NOUN
cord-301856-71syce4n	246	223	of	of	ADP
cord-301856-71syce4n	246	224	human	human	ADJ
cord-301856-71syce4n	246	225	populations	population	NOUN
cord-301856-71syce4n	246	226	key	key	ADJ
cord-301856-71syce4n	246	227	role	role	NOUN
cord-301856-71syce4n	246	228	of	of	ADP
cord-301856-71syce4n	246	229	the	the	DET
cord-301856-71syce4n	246	230	scavenger	scavenger	NOUN
cord-301856-71syce4n	246	231	receptor	receptor	NOUN
cord-301856-71syce4n	246	232	marco	marco	PROPN
cord-301856-71syce4n	246	233	in	in	ADP
cord-301856-71syce4n	246	234	mediating	mediate	VERB
cord-301856-71syce4n	246	235	adenovirus	adenovirus	NOUN
cord-301856-71syce4n	246	236	infection	infection	NOUN
cord-301856-71syce4n	246	237	and	and	CCONJ
cord-301856-71syce4n	246	238	subsequent	subsequent	ADJ
cord-301856-71syce4n	246	239	innate	innate	ADJ
cord-301856-71syce4n	246	240	responses	response	NOUN
cord-301856-71syce4n	246	241	of	of	ADP
cord-301856-71syce4n	246	242	macrophages	macrophage	NOUN
cord-301856-71syce4n	246	243	cx3cr1	cx3cr1	NOUN
cord-301856-71syce4n	246	244	-	-	PUNCT
cord-301856-71syce4n	246	245	dependent	dependent	ADJ
cord-301856-71syce4n	246	246	renal	renal	ADJ
cord-301856-71syce4n	246	247	macrophage	macrophage	NOUN
cord-301856-71syce4n	246	248	survival	survival	NOUN
cord-301856-71syce4n	246	249	promotes	promote	VERB
cord-301856-71syce4n	246	250	candida	candida	PROPN
cord-301856-71syce4n	246	251	control	control	NOUN
cord-301856-71syce4n	246	252	and	and	CCONJ
cord-301856-71syce4n	246	253	host	host	NOUN
cord-301856-71syce4n	246	254	survival	survival	NOUN
cord-301856-71syce4n	246	255	a	a	DET
cord-301856-71syce4n	246	256	mal	mal	PROPN
cord-301856-71syce4n	246	257	functional	functional	ADJ
cord-301856-71syce4n	246	258	variant	variant	NOUN
cord-301856-71syce4n	246	259	is	be	AUX
cord-301856-71syce4n	246	260	associated	associate	VERB
cord-301856-71syce4n	246	261	with	with	ADP
cord-301856-71syce4n	246	262	protection	protection	NOUN
cord-301856-71syce4n	246	263	against	against	ADP
cord-301856-71syce4n	246	264	invasive	invasive	ADJ
cord-301856-71syce4n	246	265	pneumococcal	pneumococcal	ADJ
cord-301856-71syce4n	246	266	disease	disease	NOUN
cord-301856-71syce4n	246	267	,	,	PUNCT
cord-301856-71syce4n	246	268	bacteremia	bacteremia	NOUN
cord-301856-71syce4n	246	269	,	,	PUNCT
cord-301856-71syce4n	246	270	malaria	malaria	NOUN
cord-301856-71syce4n	246	271	and	and	CCONJ
cord-301856-71syce4n	246	272	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	246	273	functional	functional	ADJ
cord-301856-71syce4n	246	274	and	and	CCONJ
cord-301856-71syce4n	246	275	genetic	genetic	ADJ
cord-301856-71syce4n	246	276	evidence	evidence	NOUN
cord-301856-71syce4n	246	277	that	that	SCONJ
cord-301856-71syce4n	246	278	the	the	DET
cord-301856-71syce4n	246	279	mal	mal	PROPN
cord-301856-71syce4n	246	280	/	/	SYM
cord-301856-71syce4n	246	281	tirap	tirap	PROPN
cord-301856-71syce4n	246	282	allele	allele	PROPN
cord-301856-71syce4n	246	283	variant	variant	PROPN
cord-301856-71syce4n	246	284	180l	180l	PROPN
cord-301856-71syce4n	246	285	has	have	AUX
cord-301856-71syce4n	246	286	been	be	AUX
cord-301856-71syce4n	246	287	selected	select	VERB
cord-301856-71syce4n	246	288	by	by	ADP
cord-301856-71syce4n	246	289	providing	provide	VERB
cord-301856-71syce4n	246	290	protection	protection	NOUN
cord-301856-71syce4n	246	291	against	against	ADP
cord-301856-71syce4n	246	292	septic	septic	ADJ
cord-301856-71syce4n	246	293	shock	shock	NOUN
cord-301856-71syce4n	246	294	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	246	295	genetics	genetic	NOUN
cord-301856-71syce4n	246	296	evidence	evidence	NOUN
cord-301856-71syce4n	246	297	of	of	ADP
cord-301856-71syce4n	246	298	an	an	DET
cord-301856-71syce4n	246	299	essential	essential	ADJ
cord-301856-71syce4n	246	300	,	,	PUNCT
cord-301856-71syce4n	246	301	nonredundant	nonredundant	ADJ
cord-301856-71syce4n	246	302	role	role	NOUN
cord-301856-71syce4n	246	303	of	of	ADP
cord-301856-71syce4n	246	304	the	the	DET
cord-301856-71syce4n	246	305	ifn	ifn	NOUN
cord-301856-71syce4n	246	306	-	-	PUNCT
cord-301856-71syce4n	246	307	g	g	NOUN
cord-301856-71syce4n	246	308	pathway	pathway	NOUN
cord-301856-71syce4n	246	309	in	in	ADP
cord-301856-71syce4n	246	310	protective	protective	ADJ
cord-301856-71syce4n	246	311	immunity	immunity	NOUN
cord-301856-71syce4n	246	312	ifng	ifng	PROPN
cord-301856-71syce4n	246	313	+874t	+874t	PROPN
cord-301856-71syce4n	246	314	/	/	SYM
cord-301856-71syce4n	246	315	a	a	DET
cord-301856-71syce4n	246	316	polymorphism	polymorphism	NOUN
cord-301856-71syce4n	246	317	and	and	CCONJ
cord-301856-71syce4n	246	318	cytokine	cytokine	NOUN
cord-301856-71syce4n	246	319	plasma	plasma	NOUN
cord-301856-71syce4n	246	320	levels	level	NOUN
cord-301856-71syce4n	246	321	are	be	AUX
cord-301856-71syce4n	246	322	associated	associate	VERB
cord-301856-71syce4n	246	323	with	with	ADP
cord-301856-71syce4n	246	324	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	246	325	to	to	PART
cord-301856-71syce4n	246	326	mycobacterium	mycobacterium	VERB
cord-301856-71syce4n	246	327	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	246	328	infection	infection	NOUN
cord-301856-71syce4n	246	329	and	and	CCONJ
cord-301856-71syce4n	246	330	clinical	clinical	ADJ
cord-301856-71syce4n	246	331	manifestation	manifestation	NOUN
cord-301856-71syce4n	246	332	of	of	ADP
cord-301856-71syce4n	246	333	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	246	334	a	a	DET
cord-301856-71syce4n	246	335	single	single	ADJ
cord-301856-71syce4n	246	336	nucleotide	nucleotide	NOUN
cord-301856-71syce4n	246	337	polymorphism	polymorphism	NOUN
cord-301856-71syce4n	246	338	in	in	ADP
cord-301856-71syce4n	246	339	the	the	DET
cord-301856-71syce4n	246	340	interferon	interferon	PROPN
cord-301856-71syce4n	246	341	-	-	PUNCT
cord-301856-71syce4n	246	342	g	g	NOUN
cord-301856-71syce4n	246	343	gene	gene	NOUN
cord-301856-71syce4n	246	344	(	(	PUNCT
cord-301856-71syce4n	246	345	ifng	ifng	PROPN
cord-301856-71syce4n	246	346	+874	+874	PROPN
cord-301856-71syce4n	246	347	t	t	PROPN
cord-301856-71syce4n	246	348	/	/	SYM
cord-301856-71syce4n	246	349	a	a	PRON
cord-301856-71syce4n	246	350	)	)	PUNCT
cord-301856-71syce4n	246	351	is	be	AUX
cord-301856-71syce4n	246	352	associated	associate	VERB
cord-301856-71syce4n	246	353	with	with	ADP
cord-301856-71syce4n	246	354	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	246	355	to	to	ADP
cord-301856-71syce4n	246	356	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	246	357	genetic	genetic	ADJ
cord-301856-71syce4n	246	358	evidence	evidence	NOUN
cord-301856-71syce4n	246	359	for	for	ADP
cord-301856-71syce4n	246	360	two	two	NUM
cord-301856-71syce4n	246	361	founding	found	VERB
cord-301856-71syce4n	246	362	populations	population	NOUN
cord-301856-71syce4n	246	363	of	of	ADP
cord-301856-71syce4n	246	364	the	the	DET
cord-301856-71syce4n	246	365	americas	america	NOUN
cord-301856-71syce4n	246	366	the	the	DET
cord-301856-71syce4n	246	367	significance	significance	NOUN
cord-301856-71syce4n	246	368	of	of	ADP
cord-301856-71syce4n	246	369	disease	disease	NOUN
cord-301856-71syce4n	246	370	in	in	ADP
cord-301856-71syce4n	246	371	the	the	DET
cord-301856-71syce4n	246	372	extinction	extinction	NOUN
cord-301856-71syce4n	246	373	of	of	ADP
cord-301856-71syce4n	246	374	the	the	DET
cord-301856-71syce4n	246	375	new	new	PROPN
cord-301856-71syce4n	246	376	england	england	PROPN
cord-301856-71syce4n	246	377	indians	indians	PROPN
cord-301856-71syce4n	246	378	a	a	DET
cord-301856-71syce4n	246	379	time	time	NOUN
cord-301856-71syce4n	246	380	transect	transect	NOUN
cord-301856-71syce4n	246	381	of	of	ADP
cord-301856-71syce4n	246	382	exomes	exome	NOUN
cord-301856-71syce4n	246	383	from	from	ADP
cord-301856-71syce4n	246	384	a	a	DET
cord-301856-71syce4n	246	385	native	native	ADJ
cord-301856-71syce4n	246	386	american	american	ADJ
cord-301856-71syce4n	246	387	population	population	NOUN
cord-301856-71syce4n	246	388	before	before	ADP
cord-301856-71syce4n	246	389	and	and	CCONJ
cord-301856-71syce4n	246	390	after	after	ADP
cord-301856-71syce4n	246	391	european	european	ADJ
cord-301856-71syce4n	246	392	contact	contact	NOUN
cord-301856-71syce4n	246	393	mortality	mortality	NOUN
cord-301856-71syce4n	246	394	from	from	ADP
cord-301856-71syce4n	246	395	contactrelated	contactrelated	ADJ
cord-301856-71syce4n	246	396	epidemics	epidemic	NOUN
cord-301856-71syce4n	246	397	among	among	ADP
cord-301856-71syce4n	246	398	indigenous	indigenous	ADJ
cord-301856-71syce4n	246	399	populations	population	NOUN
cord-301856-71syce4n	246	400	in	in	ADP
cord-301856-71syce4n	246	401	greater	great	ADJ
cord-301856-71syce4n	246	402	amazonia	amazonia	NOUN
cord-301856-71syce4n	246	403	genetic	genetic	ADJ
cord-301856-71syce4n	246	404	control	control	NOUN
cord-301856-71syce4n	246	405	of	of	ADP
cord-301856-71syce4n	246	406	survival	survival	NOUN
cord-301856-71syce4n	246	407	in	in	ADP
cord-301856-71syce4n	246	408	epidemics	epidemic	NOUN
cord-301856-71syce4n	246	409	differential	differential	ADJ
cord-301856-71syce4n	246	410	distribution	distribution	NOUN
cord-301856-71syce4n	246	411	of	of	ADP
cord-301856-71syce4n	246	412	allelic	allelic	ADJ
cord-301856-71syce4n	246	413	variants	variant	NOUN
cord-301856-71syce4n	246	414	in	in	ADP
cord-301856-71syce4n	246	415	cytokine	cytokine	NOUN
cord-301856-71syce4n	246	416	genes	gene	NOUN
cord-301856-71syce4n	246	417	among	among	ADP
cord-301856-71syce4n	246	418	african	african	ADJ
cord-301856-71syce4n	246	419	americans	americans	PROPN
cord-301856-71syce4n	246	420	and	and	CCONJ
cord-301856-71syce4n	246	421	white	white	ADJ
cord-301856-71syce4n	246	422	americans	americans	PROPN
cord-301856-71syce4n	246	423	genome	genome	NOUN
cord-301856-71syce4n	246	424	-	-	PUNCT
cord-301856-71syce4n	246	425	wide	wide	ADJ
cord-301856-71syce4n	246	426	association	association	NOUN
cord-301856-71syce4n	246	427	and	and	CCONJ
cord-301856-71syce4n	246	428	population	population	NOUN
cord-301856-71syce4n	246	429	genetic	genetic	ADJ
cord-301856-71syce4n	246	430	analysis	analysis	NOUN
cord-301856-71syce4n	246	431	of	of	ADP
cord-301856-71syce4n	246	432	c	c	X
cord-301856-71syce4n	246	433	-	-	PUNCT
cord-301856-71syce4n	246	434	reactive	reactive	ADJ
cord-301856-71syce4n	246	435	protein	protein	NOUN
cord-301856-71syce4n	246	436	in	in	ADP
cord-301856-71syce4n	246	437	african	african	PROPN
cord-301856-71syce4n	246	438	american	american	PROPN
cord-301856-71syce4n	246	439	and	and	CCONJ
cord-301856-71syce4n	246	440	hispanic	hispanic	PROPN
cord-301856-71syce4n	246	441	american	american	ADJ
cord-301856-71syce4n	246	442	women	woman	NOUN
cord-301856-71syce4n	246	443	the	the	DET
cord-301856-71syce4n	246	444	prevalence	prevalence	NOUN
cord-301856-71syce4n	246	445	of	of	ADP
cord-301856-71syce4n	246	446	atherosclerosis	atherosclerosis	NOUN
cord-301856-71syce4n	246	447	in	in	ADP
cord-301856-71syce4n	246	448	those	those	PRON
cord-301856-71syce4n	246	449	with	with	ADP
cord-301856-71syce4n	246	450	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	246	451	connective	connective	ADJ
cord-301856-71syce4n	246	452	tissue	tissue	NOUN
cord-301856-71syce4n	246	453	disease	disease	NOUN
cord-301856-71syce4n	246	454	by	by	ADP
cord-301856-71syce4n	246	455	race	race	NOUN
cord-301856-71syce4n	246	456	,	,	PUNCT
cord-301856-71syce4n	246	457	age	age	NOUN
cord-301856-71syce4n	246	458	and	and	CCONJ
cord-301856-71syce4n	246	459	traditional	traditional	ADJ
cord-301856-71syce4n	246	460	risk	risk	NOUN
cord-301856-71syce4n	246	461	factors	factor	NOUN
cord-301856-71syce4n	246	462	group	group	NOUN
cord-301856-71syce4n	246	463	differences	difference	NOUN
cord-301856-71syce4n	246	464	in	in	ADP
cord-301856-71syce4n	246	465	proneness	proneness	NOUN
cord-301856-71syce4n	246	466	to	to	PART
cord-301856-71syce4n	246	467	inflammation	inflammation	VERB
cord-301856-71syce4n	246	468	the	the	DET
cord-301856-71syce4n	246	469	contribution	contribution	NOUN
cord-301856-71syce4n	246	470	of	of	ADP
cord-301856-71syce4n	246	471	natural	natural	ADJ
cord-301856-71syce4n	246	472	selection	selection	NOUN
cord-301856-71syce4n	246	473	to	to	ADP
cord-301856-71syce4n	246	474	present	present	ADJ
cord-301856-71syce4n	246	475	-	-	PUNCT
cord-301856-71syce4n	246	476	day	day	NOUN
cord-301856-71syce4n	246	477	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	246	478	to	to	PART
cord-301856-71syce4n	246	479	chronic	chronic	VERB
cord-301856-71syce4n	246	480	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	246	481	and	and	CCONJ
cord-301856-71syce4n	246	482	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	246	483	disease	disease	NOUN
cord-301856-71syce4n	246	484	an	an	DET
cord-301856-71syce4n	246	485	integrated	integrate	VERB
cord-301856-71syce4n	246	486	catalog	catalog	NOUN
cord-301856-71syce4n	246	487	of	of	ADP
cord-301856-71syce4n	246	488	reference	reference	NOUN
cord-301856-71syce4n	246	489	genes	gene	NOUN
cord-301856-71syce4n	246	490	in	in	ADP
cord-301856-71syce4n	246	491	the	the	DET
cord-301856-71syce4n	246	492	human	human	ADJ
cord-301856-71syce4n	246	493	gut	gut	NOUN
cord-301856-71syce4n	246	494	microbiome	microbiome	NOUN
cord-301856-71syce4n	246	495	gut	gut	NOUN
cord-301856-71syce4n	246	496	microbiome	microbiome	NOUN
cord-301856-71syce4n	246	497	of	of	ADP
cord-301856-71syce4n	246	498	coexisting	coexist	VERB
cord-301856-71syce4n	246	499	baaka	baaka	PROPN
cord-301856-71syce4n	246	500	pygmies	pygmy	NOUN
cord-301856-71syce4n	246	501	and	and	CCONJ
cord-301856-71syce4n	246	502	bantu	bantu	NOUN
cord-301856-71syce4n	246	503	reflects	reflect	VERB
cord-301856-71syce4n	246	504	gradients	gradient	NOUN
cord-301856-71syce4n	246	505	of	of	ADP
cord-301856-71syce4n	246	506	traditional	traditional	ADJ
cord-301856-71syce4n	246	507	subsistence	subsistence	NOUN
cord-301856-71syce4n	246	508	patterns	pattern	NOUN
cord-301856-71syce4n	246	509	gut	gut	VERB
cord-301856-71syce4n	246	510	microbiota	microbiota	NOUN
cord-301856-71syce4n	246	511	is	be	AUX
cord-301856-71syce4n	246	512	associated	associate	VERB
cord-301856-71syce4n	246	513	with	with	ADP
cord-301856-71syce4n	246	514	obesity	obesity	NOUN
cord-301856-71syce4n	246	515	and	and	CCONJ
cord-301856-71syce4n	246	516	cardiometabolic	cardiometabolic	NOUN
cord-301856-71syce4n	246	517	disease	disease	NOUN
cord-301856-71syce4n	246	518	in	in	ADP
cord-301856-71syce4n	246	519	a	a	DET
cord-301856-71syce4n	246	520	population	population	NOUN
cord-301856-71syce4n	246	521	in	in	ADP
cord-301856-71syce4n	246	522	the	the	DET
cord-301856-71syce4n	246	523	midst	midst	NOUN
cord-301856-71syce4n	246	524	of	of	ADP
cord-301856-71syce4n	246	525	the	the	DET
cord-301856-71syce4n	246	526	good	good	ADJ
cord-301856-71syce4n	246	527	viruses	virus	NOUN
cord-301856-71syce4n	246	528	:	:	PUNCT
cord-301856-71syce4n	246	529	viral	viral	ADJ
cord-301856-71syce4n	246	530	mutualistic	mutualistic	ADJ
cord-301856-71syce4n	246	531	symbioses	symbiose	NOUN
cord-301856-71syce4n	246	532	virolution	virolution	NOUN
cord-301856-71syce4n	246	533	:	:	PUNCT
cord-301856-71syce4n	246	534	the	the	DET
cord-301856-71syce4n	246	535	most	most	ADV
cord-301856-71syce4n	246	536	important	important	ADJ
cord-301856-71syce4n	246	537	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	246	538	book	book	NOUN
cord-301856-71syce4n	246	539	since	since	SCONJ
cord-301856-71syce4n	246	540	dawkins	dawkin	NOUN
cord-301856-71syce4n	246	541	'	'	PART
cord-301856-71syce4n	246	542	selfish	selfish	ADJ
cord-301856-71syce4n	246	543	gene	gene	NOUN
cord-301856-71syce4n	246	544	to	to	ADP
cord-301856-71syce4n	246	545	erv	erv	PROPN
cord-301856-71syce4n	246	546	is	be	AUX
cord-301856-71syce4n	246	547	human	human	ADJ
cord-301856-71syce4n	246	548	:	:	PUNCT
cord-301856-71syce4n	246	549	a	a	DET
cord-301856-71syce4n	246	550	phenotype	phenotype	NOUN
cord-301856-71syce4n	246	551	-	-	PUNCT
cord-301856-71syce4n	246	552	wide	wide	ADJ
cord-301856-71syce4n	246	553	scan	scan	ADJ
cord-301856-71syce4n	246	554	linking	link	VERB
cord-301856-71syce4n	246	555	polymorphic	polymorphic	ADJ
cord-301856-71syce4n	246	556	human	human	ADJ
cord-301856-71syce4n	246	557	endogenous	endogenous	ADJ
cord-301856-71syce4n	246	558	retrovirus	retrovirus	NOUN
cord-301856-71syce4n	246	559	-	-	PUNCT
cord-301856-71syce4n	246	560	k	k	PROPN
cord-301856-71syce4n	246	561	insertions	insertion	NOUN
cord-301856-71syce4n	246	562	to	to	ADP
cord-301856-71syce4n	246	563	complex	complex	ADJ
cord-301856-71syce4n	246	564	phenotypes	phenotype	NOUN
cord-301856-71syce4n	246	565	regulatory	regulatory	ADJ
cord-301856-71syce4n	246	566	evolution	evolution	NOUN
cord-301856-71syce4n	246	567	of	of	ADP
cord-301856-71syce4n	246	568	innate	innate	ADJ
cord-301856-71syce4n	246	569	immunity	immunity	NOUN
cord-301856-71syce4n	246	570	through	through	ADP
cord-301856-71syce4n	246	571	co	co	NOUN
cord-301856-71syce4n	246	572	-	-	NOUN
cord-301856-71syce4n	246	573	option	option	NOUN
cord-301856-71syce4n	246	574	of	of	ADP
cord-301856-71syce4n	246	575	endogenous	endogenous	ADJ
cord-301856-71syce4n	246	576	retroviruses	retrovirus	NOUN
cord-301856-71syce4n	246	577	cytomegalovirus	cytomegalovirus	PROPN
cord-301856-71syce4n	246	578	infection	infection	NOUN
cord-301856-71syce4n	246	579	in	in	ADP
cord-301856-71syce4n	246	580	hiv	hiv	PROPN
cord-301856-71syce4n	246	581	-	-	PUNCT
cord-301856-71syce4n	246	582	infected	infect	VERB
cord-301856-71syce4n	246	583	and	and	CCONJ
cord-301856-71syce4n	246	584	uninfected	uninfected	ADJ
cord-301856-71syce4n	246	585	individuals	individual	NOUN
cord-301856-71syce4n	246	586	is	be	AUX
cord-301856-71syce4n	246	587	characterized	characterize	VERB
cord-301856-71syce4n	246	588	by	by	ADP
cord-301856-71syce4n	246	589	circulating	circulate	VERB
cord-301856-71syce4n	246	590	regulatory	regulatory	ADJ
cord-301856-71syce4n	246	591	t	t	NOUN
cord-301856-71syce4n	246	592	cells	cell	NOUN
cord-301856-71syce4n	246	593	of	of	ADP
cord-301856-71syce4n	246	594	unconstrained	unconstrained	ADJ
cord-301856-71syce4n	246	595	antigenic	antigenic	ADJ
cord-301856-71syce4n	246	596	specificity	specificity	NOUN
cord-301856-71syce4n	246	597	hepatitis	hepatitis	PROPN
cord-301856-71syce4n	246	598	a	a	DET
cord-301856-71syce4n	246	599	virus	virus	NOUN
cord-301856-71syce4n	246	600	infection	infection	NOUN
cord-301856-71syce4n	246	601	suppresses	suppress	VERB
cord-301856-71syce4n	246	602	hepatitis	hepatitis	PROPN
cord-301856-71syce4n	246	603	c	c	PROPN
cord-301856-71syce4n	246	604	virus	virus	PROPN
cord-301856-71syce4n	246	605	replication	replication	NOUN
cord-301856-71syce4n	246	606	and	and	CCONJ
cord-301856-71syce4n	246	607	may	may	AUX
cord-301856-71syce4n	246	608	lead	lead	VERB
cord-301856-71syce4n	246	609	to	to	ADP
cord-301856-71syce4n	246	610	clearance	clearance	NOUN
cord-301856-71syce4n	246	611	of	of	ADP
cord-301856-71syce4n	246	612	hcv	hcv	PROPN
cord-301856-71syce4n	246	613	bacteriophage	bacteriophage	PROPN
cord-301856-71syce4n	246	614	trigger	trigger	NOUN
cord-301856-71syce4n	246	615	antiviral	antiviral	ADJ
cord-301856-71syce4n	246	616	immunity	immunity	NOUN
cord-301856-71syce4n	246	617	and	and	CCONJ
cord-301856-71syce4n	246	618	prevent	prevent	VERB
cord-301856-71syce4n	246	619	clearance	clearance	NOUN
cord-301856-71syce4n	246	620	of	of	ADP
cord-301856-71syce4n	246	621	bacterial	bacterial	ADJ
cord-301856-71syce4n	246	622	infection	infection	NOUN
cord-301856-71syce4n	246	623	pro	pro	ADJ
cord-301856-71syce4n	246	624	-	-	ADJ
cord-301856-71syce4n	246	625	and	and	CCONJ
cord-301856-71syce4n	246	626	antiinflammatory	antiinflammatory	NOUN
cord-301856-71syce4n	246	627	responses	response	NOUN
cord-301856-71syce4n	246	628	of	of	ADP
cord-301856-71syce4n	246	629	peripheral	peripheral	ADJ
cord-301856-71syce4n	246	630	blood	blood	NOUN
cord-301856-71syce4n	246	631	mononuclear	mononuclear	ADJ
cord-301856-71syce4n	246	632	cells	cell	NOUN
cord-301856-71syce4n	246	633	induced	induce	VERB
cord-301856-71syce4n	246	634	by	by	ADP
cord-301856-71syce4n	246	635	staphylococcus	staphylococcus	PROPN
cord-301856-71syce4n	246	636	aureus	aureus	PROPN
cord-301856-71syce4n	246	637	and	and	CCONJ
cord-301856-71syce4n	246	638	pseudomonas	pseudomonas	PROPN
cord-301856-71syce4n	246	639	aeruginosa	aeruginosa	PROPN
cord-301856-71syce4n	246	640	phages	phage	NOUN
cord-301856-71syce4n	246	641	host	host	NOUN
cord-301856-71syce4n	246	642	-	-	PUNCT
cord-301856-71syce4n	246	643	microbe	microbe	NOUN
cord-301856-71syce4n	246	644	interactions	interaction	NOUN
cord-301856-71syce4n	246	645	have	have	AUX
cord-301856-71syce4n	246	646	shaped	shape	VERB
cord-301856-71syce4n	246	647	the	the	DET
cord-301856-71syce4n	246	648	genetic	genetic	ADJ
cord-301856-71syce4n	246	649	architecture	architecture	NOUN
cord-301856-71syce4n	246	650	of	of	ADP
cord-301856-71syce4n	246	651	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	246	652	bowel	bowel	NOUN
cord-301856-71syce4n	246	653	disease	disease	NOUN
cord-301856-71syce4n	246	654	genetics	genetic	NOUN
cord-301856-71syce4n	246	655	of	of	ADP
cord-301856-71syce4n	246	656	autoimmune	autoimmune	ADJ
cord-301856-71syce4n	246	657	diseases	disease	NOUN
cord-301856-71syce4n	246	658	:	:	PUNCT
cord-301856-71syce4n	246	659	insights	insight	NOUN
cord-301856-71syce4n	246	660	from	from	ADP
cord-301856-71syce4n	246	661	population	population	NOUN
cord-301856-71syce4n	246	662	genetics	genetic	NOUN
cord-301856-71syce4n	246	663	common	common	ADJ
cord-301856-71syce4n	246	664	risk	risk	NOUN
cord-301856-71syce4n	246	665	alleles	allele	NOUN
cord-301856-71syce4n	246	666	for	for	ADP
cord-301856-71syce4n	246	667	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	246	668	diseases	disease	NOUN
cord-301856-71syce4n	246	669	are	be	AUX
cord-301856-71syce4n	246	670	targets	target	NOUN
cord-301856-71syce4n	246	671	of	of	ADP
cord-301856-71syce4n	246	672	recent	recent	ADJ
cord-301856-71syce4n	246	673	positive	positive	ADJ
cord-301856-71syce4n	246	674	selection	selection	NOUN
cord-301856-71syce4n	246	675	signatures	signature	NOUN
cord-301856-71syce4n	246	676	of	of	ADP
cord-301856-71syce4n	246	677	environmental	environmental	ADJ
cord-301856-71syce4n	246	678	genetic	genetic	ADJ
cord-301856-71syce4n	246	679	adaptation	adaptation	NOUN
cord-301856-71syce4n	246	680	pinpoint	pinpoint	VERB
cord-301856-71syce4n	246	681	pathogens	pathogen	NOUN
cord-301856-71syce4n	246	682	as	as	ADP
cord-301856-71syce4n	246	683	the	the	DET
cord-301856-71syce4n	246	684	main	main	ADJ
cord-301856-71syce4n	246	685	selective	selective	ADJ
cord-301856-71syce4n	246	686	pressure	pressure	NOUN
cord-301856-71syce4n	246	687	through	through	ADP
cord-301856-71syce4n	246	688	human	human	ADJ
cord-301856-71syce4n	246	689	evolution	evolution	NOUN
cord-301856-71syce4n	246	690	a	a	DET
cord-301856-71syce4n	246	691	map	map	NOUN
cord-301856-71syce4n	246	692	of	of	ADP
cord-301856-71syce4n	246	693	recent	recent	ADJ
cord-301856-71syce4n	246	694	positive	positive	ADJ
cord-301856-71syce4n	246	695	selection	selection	NOUN
cord-301856-71syce4n	246	696	in	in	ADP
cord-301856-71syce4n	246	697	the	the	DET
cord-301856-71syce4n	246	698	human	human	ADJ
cord-301856-71syce4n	246	699	genome	genome	NOUN
cord-301856-71syce4n	246	700	genes	gene	NOUN
cord-301856-71syce4n	246	701	associated	associate	VERB
cord-301856-71syce4n	246	702	with	with	ADP
cord-301856-71syce4n	246	703	sle	sle	PROPN
cord-301856-71syce4n	246	704	are	be	AUX
cord-301856-71syce4n	246	705	targets	target	NOUN
cord-301856-71syce4n	246	706	of	of	ADP
cord-301856-71syce4n	246	707	recent	recent	ADJ
cord-301856-71syce4n	246	708	positive	positive	ADJ
cord-301856-71syce4n	246	709	selection	selection	NOUN
cord-301856-71syce4n	246	710	end	end	NOUN
cord-301856-71syce4n	246	711	-	-	PUNCT
cord-301856-71syce4n	246	712	stage	stage	NOUN
cord-301856-71syce4n	246	713	renal	renal	ADJ
cord-301856-71syce4n	246	714	disease	disease	NOUN
cord-301856-71syce4n	246	715	in	in	ADP
cord-301856-71syce4n	246	716	african	african	ADJ
cord-301856-71syce4n	246	717	americans	americans	PROPN
cord-301856-71syce4n	246	718	with	with	ADP
cord-301856-71syce4n	246	719	lupus	lupus	PROPN
cord-301856-71syce4n	246	720	nephritis	nephritis	PROPN
cord-301856-71syce4n	246	721	is	be	AUX
cord-301856-71syce4n	246	722	associated	associate	VERB
cord-301856-71syce4n	246	723	with	with	ADP
cord-301856-71syce4n	246	724	apol1	apol1	ADV
cord-301856-71syce4n	246	725	systemic	systemic	ADJ
cord-301856-71syce4n	246	726	lupus	lupus	NOUN
cord-301856-71syce4n	246	727	erythematosus	erythematosus	NOUN
cord-301856-71syce4n	246	728	-	-	PUNCT
cord-301856-71syce4n	246	729	associated	associate	VERB
cord-301856-71syce4n	246	730	defects	defect	NOUN
cord-301856-71syce4n	246	731	in	in	ADP
cord-301856-71syce4n	246	732	the	the	DET
cord-301856-71syce4n	246	733	inhibitory	inhibitory	ADJ
cord-301856-71syce4n	246	734	receptor	receptor	NOUN
cord-301856-71syce4n	246	735	fc	fc	PROPN
cord-301856-71syce4n	246	736	riib	riib	NOUN
cord-301856-71syce4n	246	737	reduce	reduce	VERB
cord-301856-71syce4n	246	738	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	246	739	to	to	ADP
cord-301856-71syce4n	246	740	malaria	malaria	NOUN
cord-301856-71syce4n	246	741	inherited	inherit	VERB
cord-301856-71syce4n	246	742	determinants	determinant	NOUN
cord-301856-71syce4n	246	743	of	of	ADP
cord-301856-71syce4n	246	744	crohn	crohn	PROPN
cord-301856-71syce4n	246	745	's	's	PART
cord-301856-71syce4n	246	746	disease	disease	NOUN
cord-301856-71syce4n	246	747	and	and	CCONJ
cord-301856-71syce4n	246	748	ulcerative	ulcerative	ADJ
cord-301856-71syce4n	246	749	colitis	colitis	NOUN
cord-301856-71syce4n	246	750	phenotypes	phenotype	NOUN
cord-301856-71syce4n	246	751	:	:	PUNCT
cord-301856-71syce4n	246	752	a	a	DET
cord-301856-71syce4n	246	753	genetic	genetic	ADJ
cord-301856-71syce4n	246	754	association	association	NOUN
cord-301856-71syce4n	246	755	study	study	NOUN
cord-301856-71syce4n	246	756	newly	newly	ADV
cord-301856-71syce4n	246	757	identified	identify	VERB
cord-301856-71syce4n	246	758	genetic	genetic	ADJ
cord-301856-71syce4n	246	759	risk	risk	NOUN
cord-301856-71syce4n	246	760	variants	variant	NOUN
cord-301856-71syce4n	246	761	for	for	ADP
cord-301856-71syce4n	246	762	celiac	celiac	ADJ
cord-301856-71syce4n	246	763	disease	disease	NOUN
cord-301856-71syce4n	246	764	related	relate	VERB
cord-301856-71syce4n	246	765	to	to	ADP
cord-301856-71syce4n	246	766	the	the	DET
cord-301856-71syce4n	246	767	immune	immune	ADJ
cord-301856-71syce4n	246	768	response	response	NOUN
cord-301856-71syce4n	246	769	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	246	770	and	and	CCONJ
cord-301856-71syce4n	246	771	functional	functional	ADJ
cord-301856-71syce4n	246	772	analysis	analysis	NOUN
cord-301856-71syce4n	246	773	of	of	ADP
cord-301856-71syce4n	246	774	celiac	celiac	ADJ
cord-301856-71syce4n	246	775	risk	risk	NOUN
cord-301856-71syce4n	246	776	loci	loci	NOUN
cord-301856-71syce4n	246	777	reveals	reveal	VERB
cord-301856-71syce4n	246	778	sh2b3	sh2b3	NOUN
cord-301856-71syce4n	246	779	as	as	ADP
cord-301856-71syce4n	246	780	a	a	DET
cord-301856-71syce4n	246	781	protective	protective	ADJ
cord-301856-71syce4n	246	782	factor	factor	NOUN
cord-301856-71syce4n	246	783	against	against	ADP
cord-301856-71syce4n	246	784	bacterial	bacterial	ADJ
cord-301856-71syce4n	246	785	infection	infection	NOUN
cord-301856-71syce4n	246	786	card15	card15	NOUN
cord-301856-71syce4n	246	787	/	/	SYM
cord-301856-71syce4n	246	788	nod2	nod2	NOUN
cord-301856-71syce4n	246	789	,	,	PUNCT
cord-301856-71syce4n	246	790	cd14	cd14	PROPN
cord-301856-71syce4n	246	791	and	and	CCONJ
cord-301856-71syce4n	246	792	toll	toll	NOUN
cord-301856-71syce4n	246	793	-	-	PUNCT
cord-301856-71syce4n	246	794	like	like	ADJ
cord-301856-71syce4n	246	795	4	4	NUM
cord-301856-71syce4n	246	796	receptor	receptor	NOUN
cord-301856-71syce4n	246	797	gene	gene	NOUN
cord-301856-71syce4n	246	798	polymorphisms	polymorphism	NOUN
cord-301856-71syce4n	246	799	in	in	ADP
cord-301856-71syce4n	246	800	saudi	saudi	ADJ
cord-301856-71syce4n	246	801	patients	patient	NOUN
cord-301856-71syce4n	246	802	with	with	ADP
cord-301856-71syce4n	246	803	crohn	crohn	PROPN
cord-301856-71syce4n	246	804	's	's	PART
cord-301856-71syce4n	246	805	disease	disease	PROPN
cord-301856-71syce4n	246	806	association	association	NOUN
cord-301856-71syce4n	246	807	between	between	ADP
cord-301856-71syce4n	246	808	polymorphisms	polymorphism	NOUN
cord-301856-71syce4n	246	809	in	in	ADP
cord-301856-71syce4n	246	810	the	the	DET
cord-301856-71syce4n	246	811	toll	toll	NOUN
cord-301856-71syce4n	246	812	-	-	PUNCT
cord-301856-71syce4n	246	813	like	like	ADJ
cord-301856-71syce4n	246	814	receptor	receptor	NOUN
cord-301856-71syce4n	246	815	4	4	NUM
cord-301856-71syce4n	246	816	,	,	PUNCT
cord-301856-71syce4n	246	817	cd14	cd14	PROPN
cord-301856-71syce4n	246	818	,	,	PUNCT
cord-301856-71syce4n	246	819	and	and	CCONJ
cord-301856-71syce4n	246	820	card15	card15	X
cord-301856-71syce4n	246	821	/	/	SYM
cord-301856-71syce4n	246	822	nod2	nod2	NOUN
cord-301856-71syce4n	246	823	and	and	CCONJ
cord-301856-71syce4n	246	824	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	246	825	bowel	bowel	NOUN
cord-301856-71syce4n	246	826	disease	disease	NOUN
cord-301856-71syce4n	246	827	in	in	ADP
cord-301856-71syce4n	246	828	the	the	DET
cord-301856-71syce4n	246	829	greek	greek	ADJ
cord-301856-71syce4n	246	830	population	population	NOUN
cord-301856-71syce4n	246	831	the	the	DET
cord-301856-71syce4n	246	832	effects	effect	NOUN
cord-301856-71syce4n	246	833	of	of	ADP
cord-301856-71syce4n	246	834	growing	grow	VERB
cord-301856-71syce4n	246	835	up	up	ADP
cord-301856-71syce4n	246	836	on	on	ADP
cord-301856-71syce4n	246	837	a	a	DET
cord-301856-71syce4n	246	838	farm	farm	NOUN
cord-301856-71syce4n	246	839	on	on	ADP
cord-301856-71syce4n	246	840	adult	adult	NOUN
cord-301856-71syce4n	246	841	lung	lung	NOUN
cord-301856-71syce4n	246	842	function	function	NOUN
cord-301856-71syce4n	246	843	and	and	CCONJ
cord-301856-71syce4n	246	844	allergic	allergic	ADJ
cord-301856-71syce4n	246	845	phenotypes	phenotype	NOUN
cord-301856-71syce4n	246	846	:	:	PUNCT
cord-301856-71syce4n	246	847	an	an	DET
cord-301856-71syce4n	246	848	international	international	ADJ
cord-301856-71syce4n	246	849	population	population	NOUN
cord-301856-71syce4n	246	850	-	-	PUNCT
cord-301856-71syce4n	246	851	based	base	VERB
cord-301856-71syce4n	246	852	study	study	NOUN
cord-301856-71syce4n	246	853	innate	innate	VERB
cord-301856-71syce4n	246	854	immunity	immunity	NOUN
cord-301856-71syce4n	246	855	and	and	CCONJ
cord-301856-71syce4n	246	856	asthma	asthma	NOUN
cord-301856-71syce4n	246	857	risk	risk	NOUN
cord-301856-71syce4n	246	858	in	in	ADP
cord-301856-71syce4n	246	859	amish	amish	ADJ
cord-301856-71syce4n	246	860	and	and	CCONJ
cord-301856-71syce4n	246	861	hutterite	hutterite	ADJ
cord-301856-71syce4n	246	862	farm	farm	NOUN
cord-301856-71syce4n	246	863	children	child	NOUN
cord-301856-71syce4n	246	864	a	a	DET
cord-301856-71syce4n	246	865	causal	causal	NOUN
cord-301856-71syce4n	246	866	mechanism	mechanism	NOUN
cord-301856-71syce4n	246	867	for	for	ADP
cord-301856-71syce4n	246	868	childhood	childhood	NOUN
cord-301856-71syce4n	246	869	acute	acute	ADJ
cord-301856-71syce4n	246	870	lymphoblastic	lymphoblastic	NOUN
cord-301856-71syce4n	246	871	leukaemia	leukaemia	NOUN
cord-301856-71syce4n	246	872	association	association	NOUN
cord-301856-71syce4n	246	873	between	between	ADP
cord-301856-71syce4n	246	874	helicobacter	helicobacter	NOUN
cord-301856-71syce4n	246	875	pylori	pylori	NOUN
cord-301856-71syce4n	246	876	infection	infection	NOUN
cord-301856-71syce4n	246	877	and	and	CCONJ
cord-301856-71syce4n	246	878	multiple	multiple	ADJ
cord-301856-71syce4n	246	879	sclerosis	sclerosis	NOUN
cord-301856-71syce4n	246	880	:	:	PUNCT
cord-301856-71syce4n	246	881	a	a	DET
cord-301856-71syce4n	246	882	systematic	systematic	ADJ
cord-301856-71syce4n	246	883	review	review	NOUN
cord-301856-71syce4n	246	884	and	and	CCONJ
cord-301856-71syce4n	246	885	meta	meta	NOUN
cord-301856-71syce4n	246	886	-	-	PUNCT
cord-301856-71syce4n	246	887	analysis	analysis	NOUN
cord-301856-71syce4n	246	888	is	be	AUX
cord-301856-71syce4n	246	889	toxoplasma	toxoplasma	ADJ
cord-301856-71syce4n	246	890	gondii	gondii	NOUN
cord-301856-71syce4n	246	891	infection	infection	NOUN
cord-301856-71syce4n	246	892	protective	protective	ADJ
cord-301856-71syce4n	246	893	against	against	ADP
cord-301856-71syce4n	246	894	multiple	multiple	ADJ
cord-301856-71syce4n	246	895	sclerosis	sclerosis	NOUN
cord-301856-71syce4n	246	896	risk	risk	NOUN
cord-301856-71syce4n	246	897	?	?	PUNCT
cord-301856-71syce4n	247	1	a	a	DET
cord-301856-71syce4n	247	2	critical	critical	ADJ
cord-301856-71syce4n	247	3	view	view	NOUN
cord-301856-71syce4n	247	4	on	on	ADP
cord-301856-71syce4n	247	5	transgenerational	transgenerational	ADJ
cord-301856-71syce4n	247	6	epigenetic	epigenetic	ADJ
cord-301856-71syce4n	247	7	inheritance	inheritance	NOUN
cord-301856-71syce4n	247	8	in	in	ADP
cord-301856-71syce4n	247	9	humans	human	NOUN
cord-301856-71syce4n	247	10	the	the	DET
cord-301856-71syce4n	247	11	pirna	pirna	PROPN
cord-301856-71syce4n	247	12	pathway	pathway	NOUN
cord-301856-71syce4n	247	13	responds	respond	VERB
cord-301856-71syce4n	247	14	to	to	ADP
cord-301856-71syce4n	247	15	environmental	environmental	ADJ
cord-301856-71syce4n	247	16	signals	signal	NOUN
cord-301856-71syce4n	247	17	to	to	PART
cord-301856-71syce4n	247	18	establish	establish	VERB
cord-301856-71syce4n	247	19	intergenerational	intergenerational	ADJ
cord-301856-71syce4n	247	20	adaptation	adaptation	NOUN
cord-301856-71syce4n	247	21	to	to	PART
cord-301856-71syce4n	247	22	stress	stress	VERB
cord-301856-71syce4n	247	23	within	within	ADP
cord-301856-71syce4n	247	24	and	and	CCONJ
cord-301856-71syce4n	247	25	transgenerational	transgenerational	ADJ
cord-301856-71syce4n	247	26	immune	immune	ADJ
cord-301856-71syce4n	247	27	priming	priming	NOUN
cord-301856-71syce4n	247	28	in	in	ADP
cord-301856-71syce4n	247	29	an	an	DET
cord-301856-71syce4n	247	30	insect	insect	NOUN
cord-301856-71syce4n	247	31	to	to	ADP
cord-301856-71syce4n	247	32	a	a	DET
cord-301856-71syce4n	247	33	dna	dna	PROPN
cord-301856-71syce4n	247	34	virus	virus	NOUN
cord-301856-71syce4n	247	35	epigenetic	epigenetic	ADJ
cord-301856-71syce4n	247	36	inheritance	inheritance	NOUN
cord-301856-71syce4n	247	37	at	at	ADP
cord-301856-71syce4n	247	38	the	the	DET
cord-301856-71syce4n	247	39	agouti	agouti	NOUN
cord-301856-71syce4n	247	40	locus	locus	PROPN
cord-301856-71syce4n	247	41	in	in	ADP
cord-301856-71syce4n	247	42	the	the	DET
cord-301856-71syce4n	247	43	mouse	mouse	NOUN
cord-301856-71syce4n	247	44	genetic	genetic	ADJ
cord-301856-71syce4n	247	45	and	and	CCONJ
cord-301856-71syce4n	247	46	epigenetic	epigenetic	ADJ
cord-301856-71syce4n	247	47	variation	variation	NOUN
cord-301856-71syce4n	247	48	among	among	ADP
cord-301856-71syce4n	247	49	inbred	inbreed	VERB
cord-301856-71syce4n	247	50	mouse	mouse	NOUN
cord-301856-71syce4n	247	51	littermates	littermate	NOUN
cord-301856-71syce4n	247	52	:	:	PUNCT
cord-301856-71syce4n	247	53	identification	identification	NOUN
cord-301856-71syce4n	247	54	of	of	ADP
cord-301856-71syce4n	247	55	inter	inter	ADJ
cord-301856-71syce4n	247	56	-	-	ADJ
cord-301856-71syce4n	247	57	individual	individual	ADJ
cord-301856-71syce4n	247	58	differentially	differentially	ADV
cord-301856-71syce4n	247	59	methylated	methylate	VERB
cord-301856-71syce4n	247	60	regions	region	NOUN
cord-301856-71syce4n	247	61	chronic	chronic	ADJ
cord-301856-71syce4n	247	62	high	high	ADJ
cord-301856-71syce4n	247	63	-	-	PUNCT
cord-301856-71syce4n	247	64	fat	fat	NOUN
cord-301856-71syce4n	247	65	diet	diet	NOUN
cord-301856-71syce4n	247	66	in	in	ADP
cord-301856-71syce4n	247	67	fathers	father	NOUN
cord-301856-71syce4n	247	68	programs	programs	PROPN
cord-301856-71syce4n	247	69	b	b	X
cord-301856-71syce4n	247	70	-	-	PUNCT
cord-301856-71syce4n	247	71	cell	cell	NOUN
cord-301856-71syce4n	247	72	dysfunction	dysfunction	NOUN
cord-301856-71syce4n	247	73	in	in	ADP
cord-301856-71syce4n	247	74	female	female	ADJ
cord-301856-71syce4n	247	75	rat	rat	NOUN
cord-301856-71syce4n	247	76	offspring	offspring	NOUN
cord-301856-71syce4n	247	77	physiological	physiological	ADJ
cord-301856-71syce4n	247	78	resistance	resistance	NOUN
cord-301856-71syce4n	247	79	of	of	ADP
cord-301856-71syce4n	247	80	grasshopper	grasshopper	NOUN
cord-301856-71syce4n	247	81	mice	mouse	NOUN
cord-301856-71syce4n	247	82	(	(	PUNCT
cord-301856-71syce4n	247	83	onychomys	onychomys	PROPN
cord-301856-71syce4n	247	84	spp	spp	PROPN
cord-301856-71syce4n	247	85	.	.	PUNCT
cord-301856-71syce4n	247	86	)	)	PUNCT
cord-301856-71syce4n	248	1	to	to	ADP
cord-301856-71syce4n	248	2	arizona	arizona	PROPN
cord-301856-71syce4n	248	3	bark	bark	PROPN
cord-301856-71syce4n	248	4	scorpion	scorpion	NOUN
cord-301856-71syce4n	248	5	(	(	PUNCT
cord-301856-71syce4n	248	6	centruroides	centruroide	NOUN
cord-301856-71syce4n	248	7	exilicauda	exilicauda	NOUN
cord-301856-71syce4n	248	8	)	)	PUNCT
cord-301856-71syce4n	248	9	venom	venom	NOUN
cord-301856-71syce4n	248	10	persistent	persistent	ADJ
cord-301856-71syce4n	248	11	epigenetic	epigenetic	ADJ
cord-301856-71syce4n	248	12	differences	difference	NOUN
cord-301856-71syce4n	248	13	associated	associate	VERB
cord-301856-71syce4n	248	14	with	with	ADP
cord-301856-71syce4n	248	15	prenatal	prenatal	ADJ
cord-301856-71syce4n	248	16	exposure	exposure	NOUN
cord-301856-71syce4n	248	17	to	to	ADP
cord-301856-71syce4n	248	18	famine	famine	NOUN
cord-301856-71syce4n	248	19	in	in	ADP
cord-301856-71syce4n	248	20	humans	human	NOUN
cord-301856-71syce4n	248	21	dna	dna	NOUN
cord-301856-71syce4n	248	22	methylation	methylation	NOUN
cord-301856-71syce4n	248	23	as	as	ADP
cord-301856-71syce4n	248	24	a	a	DET
cord-301856-71syce4n	248	25	mediator	mediator	NOUN
cord-301856-71syce4n	248	26	of	of	ADP
cord-301856-71syce4n	248	27	the	the	DET
cord-301856-71syce4n	248	28	association	association	NOUN
cord-301856-71syce4n	248	29	between	between	ADP
cord-301856-71syce4n	248	30	prenatal	prenatal	ADJ
cord-301856-71syce4n	248	31	adversity	adversity	NOUN
cord-301856-71syce4n	248	32	and	and	CCONJ
cord-301856-71syce4n	248	33	risk	risk	NOUN
cord-301856-71syce4n	248	34	factors	factor	NOUN
cord-301856-71syce4n	248	35	for	for	ADP
cord-301856-71syce4n	248	36	metabolic	metabolic	ADJ
cord-301856-71syce4n	248	37	disease	disease	NOUN
cord-301856-71syce4n	248	38	in	in	ADP
cord-301856-71syce4n	248	39	adulthood	adulthood	ADJ
cord-301856-71syce4n	248	40	transgenerational	transgenerational	ADJ
cord-301856-71syce4n	248	41	effects	effect	NOUN
cord-301856-71syce4n	248	42	of	of	ADP
cord-301856-71syce4n	248	43	prenatal	prenatal	ADJ
cord-301856-71syce4n	248	44	exposure	exposure	NOUN
cord-301856-71syce4n	248	45	to	to	ADP
cord-301856-71syce4n	248	46	the	the	DET
cord-301856-71syce4n	248	47	1944	1944	NUM
cord-301856-71syce4n	248	48	-	-	SYM
cord-301856-71syce4n	248	49	45	45	NUM
cord-301856-71syce4n	248	50	dutch	dutch	ADJ
cord-301856-71syce4n	248	51	famine	famine	ADJ
cord-301856-71syce4n	248	52	analysis	analysis	NOUN
cord-301856-71syce4n	248	53	of	of	ADP
cord-301856-71syce4n	248	54	bottlenecks	bottleneck	NOUN
cord-301856-71syce4n	248	55	in	in	ADP
cord-301856-71syce4n	248	56	experimental	experimental	ADJ
cord-301856-71syce4n	248	57	models	model	NOUN
cord-301856-71syce4n	248	58	of	of	ADP
cord-301856-71syce4n	248	59	infection	infection	NOUN
cord-301856-71syce4n	248	60	haldane	haldane	PROPN
cord-301856-71syce4n	248	61	's	's	PART
cord-301856-71syce4n	248	62	the	the	DET
cord-301856-71syce4n	248	63	causes	cause	NOUN
cord-301856-71syce4n	248	64	of	of	ADP
cord-301856-71syce4n	248	65	evolution	evolution	NOUN
cord-301856-71syce4n	248	66	and	and	CCONJ
cord-301856-71syce4n	248	67	the	the	DET
cord-301856-71syce4n	248	68	modern	modern	ADJ
cord-301856-71syce4n	248	69	synthesis	synthesis	NOUN
cord-301856-71syce4n	248	70	in	in	ADP
cord-301856-71syce4n	248	71	evolutionary	evolutionary	ADJ
cord-301856-71syce4n	248	72	biology	biology	NOUN
cord-301856-71syce4n	248	73	the	the	DET
cord-301856-71syce4n	248	74	genome	genome	NOUN
cord-301856-71syce4n	248	75	of	of	ADP
cord-301856-71syce4n	248	76	the	the	DET
cord-301856-71syce4n	248	77	offspring	offspring	NOUN
cord-301856-71syce4n	248	78	of	of	ADP
cord-301856-71syce4n	248	79	a	a	DET
cord-301856-71syce4n	248	80	neanderthal	neanderthal	ADJ
cord-301856-71syce4n	248	81	mother	mother	NOUN
cord-301856-71syce4n	248	82	and	and	CCONJ
cord-301856-71syce4n	248	83	a	a	DET
cord-301856-71syce4n	248	84	denisovan	denisovan	ADJ
cord-301856-71syce4n	248	85	father	father	PROPN
cord-301856-71syce4n	248	86	timing	timing	NOUN
cord-301856-71syce4n	248	87	of	of	ADP
cord-301856-71syce4n	248	88	archaic	archaic	ADJ
cord-301856-71syce4n	248	89	hominin	hominin	PROPN
cord-301856-71syce4n	248	90	occupation	occupation	NOUN
cord-301856-71syce4n	248	91	of	of	ADP
cord-301856-71syce4n	248	92	denisova	denisova	PROPN
cord-301856-71syce4n	248	93	cave	cave	NOUN
cord-301856-71syce4n	248	94	in	in	ADP
cord-301856-71syce4n	248	95	southern	southern	ADJ
cord-301856-71syce4n	248	96	siberia	siberia	PROPN
cord-301856-71syce4n	248	97	on	on	ADP
cord-301856-71syce4n	248	98	the	the	DET
cord-301856-71syce4n	248	99	origin	origin	NOUN
cord-301856-71syce4n	248	100	of	of	ADP
cord-301856-71syce4n	248	101	modern	modern	ADJ
cord-301856-71syce4n	248	102	humans	human	NOUN
cord-301856-71syce4n	248	103	:	:	PUNCT
cord-301856-71syce4n	248	104	asian	asian	ADJ
cord-301856-71syce4n	248	105	perspectives	perspective	NOUN
cord-301856-71syce4n	248	106	early	early	ADJ
cord-301856-71syce4n	248	107	human	human	ADJ
cord-301856-71syce4n	248	108	dispersals	dispersal	NOUN
cord-301856-71syce4n	248	109	within	within	ADP
cord-301856-71syce4n	248	110	the	the	DET
cord-301856-71syce4n	248	111	americas	america	NOUN
cord-301856-71syce4n	248	112	dating	date	VERB
cord-301856-71syce4n	248	113	the	the	DET
cord-301856-71syce4n	248	114	origin	origin	NOUN
cord-301856-71syce4n	248	115	of	of	ADP
cord-301856-71syce4n	248	116	the	the	DET
cord-301856-71syce4n	248	117	ccr5	ccr5	PROPN
cord-301856-71syce4n	248	118	-	-	PUNCT
cord-301856-71syce4n	248	119	d32	d32	PROPN
cord-301856-71syce4n	248	120	aids	aid	NOUN
cord-301856-71syce4n	248	121	-	-	PUNCT
cord-301856-71syce4n	248	122	resistance	resistance	NOUN
cord-301856-71syce4n	248	123	allele	allele	NOUN
cord-301856-71syce4n	248	124	by	by	ADP
cord-301856-71syce4n	248	125	the	the	DET
cord-301856-71syce4n	248	126	coalescence	coalescence	NOUN
cord-301856-71syce4n	248	127	of	of	ADP
cord-301856-71syce4n	248	128	haplotypes	haplotype	NOUN
cord-301856-71syce4n	248	129	long	long	ADJ
cord-301856-71syce4n	248	130	-	-	PUNCT
cord-301856-71syce4n	248	131	term	term	NOUN
cord-301856-71syce4n	248	132	control	control	NOUN
cord-301856-71syce4n	248	133	of	of	ADP
cord-301856-71syce4n	248	134	hiv	hiv	PROPN
cord-301856-71syce4n	248	135	by	by	ADP
cord-301856-71syce4n	248	136	ccr5	ccr5	PROPN
cord-301856-71syce4n	248	137	delta32	delta32	PROPN
cord-301856-71syce4n	248	138	/	/	SYM
cord-301856-71syce4n	248	139	delta32	delta32	NOUN
cord-301856-71syce4n	248	140	stem	stem	NOUN
cord-301856-71syce4n	248	141	-	-	PUNCT
cord-301856-71syce4n	248	142	cell	cell	NOUN
cord-301856-71syce4n	248	143	transplantation	transplantation	NOUN
cord-301856-71syce4n	248	144	evaluating	evaluate	VERB
cord-301856-71syce4n	248	145	plague	plague	NOUN
cord-301856-71syce4n	248	146	and	and	CCONJ
cord-301856-71syce4n	248	147	smallpox	smallpox	NOUN
cord-301856-71syce4n	248	148	as	as	ADP
cord-301856-71syce4n	248	149	historical	historical	ADJ
cord-301856-71syce4n	248	150	selective	selective	ADJ
cord-301856-71syce4n	248	151	pressures	pressure	NOUN
cord-301856-71syce4n	248	152	for	for	ADP
cord-301856-71syce4n	248	153	the	the	DET
cord-301856-71syce4n	248	154	ccr5	ccr5	PROPN
cord-301856-71syce4n	248	155	-	-	PUNCT
cord-301856-71syce4n	248	156	delta	delta	PROPN
cord-301856-71syce4n	248	157	32	32	NUM
cord-301856-71syce4n	248	158	hiv	hiv	PROPN
cord-301856-71syce4n	248	159	-	-	PUNCT
cord-301856-71syce4n	248	160	resistance	resistance	PROPN
cord-301856-71syce4n	248	161	allele	allele	PROPN
cord-301856-71syce4n	248	162	reappraisal	reappraisal	NOUN
cord-301856-71syce4n	248	163	of	of	ADP
cord-301856-71syce4n	248	164	the	the	DET
cord-301856-71syce4n	248	165	historical	historical	ADJ
cord-301856-71syce4n	248	166	selective	selective	ADJ
cord-301856-71syce4n	248	167	pressures	pressure	NOUN
cord-301856-71syce4n	248	168	for	for	ADP
cord-301856-71syce4n	248	169	the	the	DET
cord-301856-71syce4n	248	170	ccr5	ccr5	PROPN
cord-301856-71syce4n	248	171	-	-	PUNCT
cord-301856-71syce4n	248	172	d32	d32	PROPN
cord-301856-71syce4n	248	173	mutation	mutation	NOUN
cord-301856-71syce4n	248	174	convergent	convergent	ADJ
cord-301856-71syce4n	248	175	evolution	evolution	NOUN
cord-301856-71syce4n	248	176	in	in	ADP
cord-301856-71syce4n	248	177	european	european	PROPN
cord-301856-71syce4n	248	178	and	and	CCONJ
cord-301856-71syce4n	248	179	rroma	rroma	PROPN
cord-301856-71syce4n	248	180	populations	population	NOUN
cord-301856-71syce4n	248	181	reveals	reveal	VERB
cord-301856-71syce4n	248	182	pressure	pressure	NOUN
cord-301856-71syce4n	248	183	exerted	exert	VERB
cord-301856-71syce4n	248	184	by	by	ADP
cord-301856-71syce4n	248	185	plague	plague	NOUN
cord-301856-71syce4n	248	186	on	on	ADP
cord-301856-71syce4n	248	187	toll	toll	NOUN
cord-301856-71syce4n	248	188	-	-	PUNCT
cord-301856-71syce4n	248	189	like	like	ADJ
cord-301856-71syce4n	248	190	receptors	receptor	VERB
cord-301856-71syce4n	248	191	small	small	ADJ
cord-301856-71syce4n	248	192	amounts	amount	NOUN
cord-301856-71syce4n	248	193	of	of	ADP
cord-301856-71syce4n	248	194	archaic	archaic	ADJ
cord-301856-71syce4n	248	195	admixture	admixture	NOUN
cord-301856-71syce4n	248	196	provide	provide	VERB
cord-301856-71syce4n	248	197	big	big	ADJ
cord-301856-71syce4n	248	198	insights	insight	NOUN
cord-301856-71syce4n	248	199	into	into	ADP
cord-301856-71syce4n	248	200	human	human	ADJ
cord-301856-71syce4n	248	201	history	history	NOUN
cord-301856-71syce4n	248	202	malaria	malaria	NOUN
cord-301856-71syce4n	248	203	in	in	ADP
cord-301856-71syce4n	248	204	east	east	PROPN
cord-301856-71syce4n	248	205	african	african	ADJ
cord-301856-71syce4n	248	206	highlands	highland	NOUN
cord-301856-71syce4n	248	207	during	during	ADP
cord-301856-71syce4n	248	208	the	the	DET
cord-301856-71syce4n	248	209	past	past	ADJ
cord-301856-71syce4n	248	210	30	30	NUM
cord-301856-71syce4n	248	211	years	year	NOUN
cord-301856-71syce4n	248	212	:	:	PUNCT
cord-301856-71syce4n	248	213	impact	impact	NOUN
cord-301856-71syce4n	248	214	of	of	ADP
cord-301856-71syce4n	248	215	environmental	environmental	ADJ
cord-301856-71syce4n	248	216	changes	change	NOUN
cord-301856-71syce4n	248	217	common	common	ADJ
cord-301856-71syce4n	248	218	west	west	PROPN
cord-301856-71syce4n	248	219	african	african	PROPN
cord-301856-71syce4n	248	220	hla	hla	PROPN
cord-301856-71syce4n	248	221	antigens	antigen	NOUN
cord-301856-71syce4n	248	222	are	be	AUX
cord-301856-71syce4n	248	223	associated	associate	VERB
cord-301856-71syce4n	248	224	with	with	ADP
cord-301856-71syce4n	248	225	protection	protection	NOUN
cord-301856-71syce4n	248	226	from	from	ADP
cord-301856-71syce4n	248	227	severe	severe	ADJ
cord-301856-71syce4n	248	228	malaria	malaria	NOUN
cord-301856-71syce4n	248	229	full	full	ADJ
cord-301856-71syce4n	248	230	-	-	PUNCT
cord-301856-71syce4n	248	231	exon	exon	NOUN
cord-301856-71syce4n	248	232	resequencing	resequencing	NOUN
cord-301856-71syce4n	248	233	reveals	reveal	VERB
cord-301856-71syce4n	248	234	toll	toll	NOUN
cord-301856-71syce4n	248	235	-	-	PUNCT
cord-301856-71syce4n	248	236	like	like	ADJ
cord-301856-71syce4n	248	237	receptor	receptor	NOUN
cord-301856-71syce4n	248	238	variants	variant	NOUN
cord-301856-71syce4n	248	239	contribute	contribute	VERB
cord-301856-71syce4n	248	240	to	to	ADP
cord-301856-71syce4n	248	241	human	human	ADJ
cord-301856-71syce4n	248	242	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	248	243	to	to	ADP
cord-301856-71syce4n	248	244	tuberculosis	tuberculosis	NOUN
cord-301856-71syce4n	248	245	disease	disease	NOUN
cord-301856-71syce4n	248	246	multiple	multiple	ADJ
cord-301856-71syce4n	248	247	common	common	ADJ
cord-301856-71syce4n	248	248	variants	variant	NOUN
cord-301856-71syce4n	248	249	for	for	ADP
cord-301856-71syce4n	248	250	celiac	celiac	ADJ
cord-301856-71syce4n	248	251	disease	disease	NOUN
cord-301856-71syce4n	248	252	influencing	influence	VERB
cord-301856-71syce4n	248	253	immune	immune	ADJ
cord-301856-71syce4n	248	254	gene	gene	NOUN
cord-301856-71syce4n	248	255	expression	expression	NOUN
cord-301856-71syce4n	248	256	epitope	epitope	NOUN
cord-301856-71syce4n	248	257	selection	selection	NOUN
cord-301856-71syce4n	248	258	for	for	ADP
cord-301856-71syce4n	248	259	hla	hla	PROPN
cord-301856-71syce4n	248	260	-	-	PUNCT
cord-301856-71syce4n	248	261	dq2	dq2	PROPN
cord-301856-71syce4n	248	262	presentation	presentation	NOUN
cord-301856-71syce4n	248	263	:	:	PUNCT
cord-301856-71syce4n	248	264	implications	implication	NOUN
cord-301856-71syce4n	248	265	for	for	ADP
cord-301856-71syce4n	248	266	celiac	celiac	ADJ
cord-301856-71syce4n	248	267	disease	disease	NOUN
cord-301856-71syce4n	248	268	and	and	CCONJ
cord-301856-71syce4n	248	269	viral	viral	ADJ
cord-301856-71syce4n	248	270	defense	defense	NOUN
cord-301856-71syce4n	248	271	card15	card15	NOUN
cord-301856-71syce4n	248	272	/	/	SYM
cord-301856-71syce4n	248	273	nod2	nod2	NOUN
cord-301856-71syce4n	248	274	mutational	mutational	ADJ
cord-301856-71syce4n	248	275	analysis	analysis	NOUN
cord-301856-71syce4n	248	276	and	and	CCONJ
cord-301856-71syce4n	248	277	genotype	genotype	NOUN
cord-301856-71syce4n	248	278	-	-	PUNCT
cord-301856-71syce4n	248	279	phenotype	phenotype	NOUN
cord-301856-71syce4n	248	280	correlation	correlation	NOUN
cord-301856-71syce4n	248	281	in	in	ADP
cord-301856-71syce4n	248	282	612	612	NUM
cord-301856-71syce4n	248	283	patients	patient	NOUN
cord-301856-71syce4n	248	284	with	with	ADP
cord-301856-71syce4n	248	285	inflammatory	inflammatory	ADJ
cord-301856-71syce4n	248	286	bowel	bowel	PROPN
cord-301856-71syce4n	248	287	disease	disease	PROPN
cord-301856-71syce4n	248	288	association	association	NOUN
cord-301856-71syce4n	248	289	of	of	ADP
cord-301856-71syce4n	248	290	nod2	nod2	PROPN
cord-301856-71syce4n	248	291	leucine	leucine	NOUN
cord-301856-71syce4n	248	292	-	-	PUNCT
cord-301856-71syce4n	248	293	rich	rich	ADJ
cord-301856-71syce4n	248	294	repeat	repeat	NOUN
cord-301856-71syce4n	248	295	variants	variant	NOUN
cord-301856-71syce4n	248	296	with	with	ADP
cord-301856-71syce4n	248	297	susceptibility	susceptibility	NOUN
cord-301856-71syce4n	248	298	to	to	ADP
cord-301856-71syce4n	248	299	crohn	crohn	PROPN
cord-301856-71syce4n	248	300	's	's	PART
cord-301856-71syce4n	248	301	disease	disease	PROPN
cord-301856-71syce4n	248	302	nod1	nod1	PROPN
cord-301856-71syce4n	248	303	and	and	CCONJ
cord-301856-71syce4n	248	304	nod2	nod2	NOUN
cord-301856-71syce4n	248	305	:	:	PUNCT
cord-301856-71syce4n	248	306	beyond	beyond	ADP
cord-301856-71syce4n	248	307	peptidoglycan	peptidoglycan	NOUN
cord-301856-71syce4n	248	308	sensing	sense	VERB
cord-301856-71syce4n	248	309	global	global	ADJ
cord-301856-71syce4n	248	310	,	,	PUNCT
cord-301856-71syce4n	248	311	regional	regional	ADJ
cord-301856-71syce4n	248	312	and	and	CCONJ
cord-301856-71syce4n	248	313	countrylevel	countrylevel	NOUN
cord-301856-71syce4n	248	314	90	90	NUM
cord-301856-71syce4n	248	315	-	-	SYM
cord-301856-71syce4n	248	316	90	90	NUM
cord-301856-71syce4n	248	317	-	-	SYM
cord-301856-71syce4n	248	318	90	90	NUM
cord-301856-71syce4n	248	319	estimates	estimate	NOUN
cord-301856-71syce4n	248	320	for	for	ADP
cord-301856-71syce4n	248	321	2018	2018	NUM
cord-301856-71syce4n	248	322	:	:	PUNCT
cord-301856-71syce4n	248	323	assessing	assess	VERB
cord-301856-71syce4n	248	324	progress	progress	NOUN
cord-301856-71syce4n	248	325	towards	towards	ADP
cord-301856-71syce4n	248	326	the	the	DET
cord-301856-71syce4n	248	327	2020	2020	NUM
cord-301856-71syce4n	248	328	targe	targe	NOUN
