item: #1 of 99 id: cord-001455-n7quwr4s author: Rapin, Noreen title: Activation of Innate Immune-Response Genes in Little Brown Bats (Myotis lucifugus) Infected with the Fungus Pseudogymnoascus destructans date: 2014-11-12 words: 3724 flesch: 45 summary: Although damage caused by the fungus is restricted to the superficial skin, infected bats clearly show signs of systemic physiological perturbation such as dehydration, hypovolemia and metabolic acidosis [24] . Infected bats arouse from torpor more frequently than uninfected bats [25, 26] possibly leading to emaciation. keywords: bats; destructans; fungal; genes; infection; levels; lucifugus; pcr; response; transcripts cache: cord-001455-n7quwr4s.txt plain text: cord-001455-n7quwr4s.txt item: #2 of 99 id: cord-003166-k3jxvzfi author: Noh, Ji Yeong title: Isolation and characterization of novel bat paramyxovirus B16-40 potentially belonging to the proposed genus Shaanvirus date: 2018-08-22 words: 4691 flesch: 45 summary: The MARC 145 cells and LLC-MK2 cells were then washed once with PBS Bats as reservoirs of severe emerging infectious diseases Detection of Severe Acute Respiratory Syndrome-Like, Middle East Respiratory Syndrome-Like Bat Coronaviruses and Group H Rotavirus in Faeces of Korean Bats Bats host major mammalian paramyxoviruses Taxonomy of the order Mononegavirales: update 2017 Hendra and Nipah infection: emerging paramyxoviruses Isolation of multiple novel paramyxoviruses from pteropid bat urine Novel paramyxoviruses in free-ranging European bats Novel paramyxoviruses in bats from sub-Saharan Africa Identification of novel paramyxoviruses in insectivorous bats of the Southwest Indian Ocean Nipah virus transmission from bats to humans associated with drinking traditional liquor made from date palm sap Serological evidence of possible human infection with Tioman virus, a newly described paramyxovirus of bat origin The complete genome sequence of J virus reveals a unique genome structure in the family Paramyxoviridae Deciphering the bat virome catalog to better understand the ecological diversity of bat viruses and the bat origin of emerging infectious diseases The immune evasion function of J and Beilong virus V proteins is distinct from that of other paramyxoviruses, consistent with their inclusion in the proposed genus Jeilongvirus Coronavirus and paramyxovirus in bats from Northwest Italy Circulation of Alphacoronavirus, Betacoronavirus and Paramyxovirus in Hipposideros bat species in Zimbabwe. In addition, novel strains of bat paramyxoviruses in diverse genera have been reported continuously [15] [16] keywords: b16; bat; bats; cross; genus; kbpv; parainfluenza; paramyxovirus; paramyxovirus b16; virus; viruses cache: cord-003166-k3jxvzfi.txt plain text: cord-003166-k3jxvzfi.txt item: #3 of 99 id: cord-003232-nquw7qga author: Kuchipudi, Suresh V. title: Novel Flu Viruses in Bats and Cattle: “Pushing the Envelope” of Influenza Infection date: 2018-08-06 words: 3855 flesch: 38 summary: A virus polymerase is a site for adaptive changes during experimental evolution in bat cells Differences in influenza virus receptors in chickens and ducks: Implications for interspecies transmission Endocytosis of influenza viruses. The genetic diversity of influenza viruses is ever increasing with more novel influenza subtypes being discovered periodically. keywords: bat; bats; cattle; host; human; iavs; influenza; virus; viruses cache: cord-003232-nquw7qga.txt plain text: cord-003232-nquw7qga.txt item: #4 of 99 id: cord-003482-f1uvohf0 author: Malmlov, Ashley title: Experimental Zika virus infection of Jamaican fruit bats (Artibeus jamaicensis) and possible entry of virus into brain via activated microglial cells date: 2019-02-04 words: 7514 flesch: 51 summary: Isolation and haemagglutination-inhibition studies on bats collected in Kenya and throughout Uganda Effect of Zika virus and Bwamba virus in the cave bat (Myotis lucifugus) Transmission studies of Hendra virus (equine morbillivirus) in the fruit bats, horses and cats Pteropid bats are confirmed as the reservoir hosts of henipaviruses: A comprehensive experimental study of virus transmission Antibody-mediated immune response in the bat, Pteropus giganteus Detection of specfic antibody responses to vaccinatin in variable flying foxes (Pteropus hypomelanus) The little brown bat, M. lucifugus, displays a highly diverse VH, DH, JH repertoire but little evidence of somatic hypermutation Tacaribe virus cases fatal infection of an ostensible reservoir host, the Jamaican fruit bat Replication and shedding of MERS-CoV in Jamaican fruit bats (Artibeus jamaicensis) Transcriptomic signatures of tacaribe virus-infected Jamaican fruit bats Assay optimization for molecular detection of Zika virus A rhesus macaque model of Asian-lineage Zika virus infection Zika virus testing considerations: lessons learned from the first eighty real-time RT-PCR-positive cases diagnosed in New York State Detection of Zika virus in urine Long-term kinetics of Zika virus RNA and antibodies in body fluids of a vasectomized traveller returning from Martinique: a case report Persistence of Zika virus in body fluids-Preliminary report Zika virus causes testis damage and leads to male infertility in mice Zika virus infection damages the testes in mice A mouse model of Zika virus pathogenesis Zika viral infection and neutralizing human antibody response in a BLT humanized mouse model Notes from the field: Evidence of Zika virus infection in brain and placental tissues from two congenitally infected newborns and two fetal losses-Brazil Zika virus damages the human placental barrier and presents marked fetal neurotropism Pathology of congenital Zika syndrome in Brazil: a case series Zika virus infection of rhesus macaques leads to viral persistence in multiple tissues Fetal brain lesions after subcutaneous inoculation of Zika virus in a pregnant nonhuman primate Nonhuman primate models of Zika virus infection, immunity, and therapeutic development Zika viral dynamics and shedding in rhesus and cynomolgus macaques Overview of the current status of Zika virus pathogenesis and animal related research Axl mediates Zika virus entry in human glial cells and modulates innate immune responses Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity Entry sites of Venezuelan and western equine encephalitis viruses in the mouse central nervous system following peripheral infection Detection of Zika virus in saliva Biology of Zika virus infection in human skin cells Denge virus in Mexican bats Neotropical bats that co-habit with humans function as dead-end hosts for dengue virus Detection of dengue virus neutralizing antibodies in bats from Costa Rica and Ecuador Sylvatic transmission of arboviruses among bornean orangutans Zika virus, vectors, reservoirs, amplifying hosts, and their potential to spread worldwide: what we know and what we should investigate urgently A sero-epidemiological survey for certain arboviruses (Togaviridae) in Pakistan Investigating the potential role of North American animals as hosts for Zika virus. Distribution of viral antigen in bat tissues suggests that infection in this species recapitulates human infection, which is thought to start with infection of epidermal and dermal cells with subsequent dissemination to multiple organs including salivary glands as viral RNA can be detected in human saliva [44, 45] . keywords: animal; bats; brain; cells; dpi; fruit; human; infection; rna; serum; study; time; tissues; urine; virus; zika; zikv cache: cord-003482-f1uvohf0.txt plain text: cord-003482-f1uvohf0.txt item: #5 of 99 id: cord-003757-uwbpbai7 author: Chionh, Yok Teng title: High basal heat-shock protein expression in bats confers resistance to cellular heat/oxidative stress date: 2019-06-22 words: 7735 flesch: 49 summary: Consequently, bat cells survive prolonged heat treatment, along with other stress stimuli, in a HSP-dependent manner, whereas other mammalian cells succumbed. To confirm heat tolerance at the cellular level, as predicted by elevated core body temperature during flight, bat cells were subjected to prolonged heat stress. keywords: alecto; bat; bats; cells; et al; expression; fig; heat; hsp70; hsps; human; levels; lines; protein; shock; species; spelaea; stress cache: cord-003757-uwbpbai7.txt plain text: cord-003757-uwbpbai7.txt item: #6 of 99 id: cord-003775-1axsebya author: Lelli, Davide title: Hypsugopoxvirus: A Novel Poxvirus Isolated from Hypsugo savii in Italy date: 2019-06-19 words: 3010 flesch: 41 summary: Rapid annotation of viral genomes using a closely related reference genome A real-time PCR assay for bat SARS-like coronavirus detection and its application to Italian greater horseshoe bat faecal sample surveys Alpha and lineage C betaCoV infections in Italian bats Detection and full genome characterization of two beta CoV viruses related to Middle East respiratory syndrome from bats in Italy Full genome characterization of two novel Alpha-coronavirus species from Italian bats Active and passive surveillance for bat lyssaviruses in Italy revealed serological evidence for their circulation in three bat species Detection and phylogenetic characterization of astroviruses in insectivorous bats from Central-Southern Italy Cotia virus: A new agent isolated from sentinel mice in Sao Paulo Biological characterization and next-generation genome sequencing of the unclassified Cotia virus SPAn232 (Poxviridae) Dead bats from different species were collected for virological investigations from wild animal rescue/rehabilitation centers in the context of a general surveillance project that has been implemented in Northern Italy since 2009-2010, which focuses on the detection of emerging bat viruses [14] keywords: analysis; bat; bats; eptv; genome; hypv; italy; poxvirus; viruses cache: cord-003775-1axsebya.txt plain text: cord-003775-1axsebya.txt item: #7 of 99 id: cord-004502-3mkv3bal author: Wei, Gang title: Indirubin, a small molecular deriving from connectivity map (CMAP) screening, ameliorates obesity-induced metabolic dysfunction by enhancing brown adipose thermogenesis and white adipose browning date: 2020-03-16 words: 9778 flesch: 43 summary: In the present study, our results showed that indirubin treatment remarkably reduced body weight gain and adiposity and improved whole-body metabolism in HFD mice, but there was no significant difference on normal chow diet conditions (Fig. 2) . Consistent with these results, indirubin treated mice under HFD also displayed improved glucose handling as determined by glucose and insulin tolerance tests (at weeks 10 and 12, respectively) ( Fig. keywords: activity; adipocytes; adipose; bat; brown; expression; fat; fig; genes; hfd; indirubin; levels; mice; ncd; obesity; swat; thermogenesis; treatment; ucp1; vehicle cache: cord-004502-3mkv3bal.txt plain text: cord-004502-3mkv3bal.txt item: #8 of 99 id: cord-004510-cbutpjre author: Seetahal, Janine F. R. title: The Serological Prevalence of Rabies Virus-Neutralizing Antibodies in the Bat Population on the Caribbean Island of Trinidad date: 2020-02-05 words: 6432 flesch: 39 summary: Taken together with the ubiquity of the Artibeus species throughout the Caribbean [78] the presence or introduction of RABV into other Caribbean islands previously thought to be free of bat rabies is plausible. Vector Borne Zoonotic Dis Host and viral ecology determine bat rabies seasonality and maintenance Evidence for prenatal transfer of rabies virus in the Mexican free-tailed bat (Tadarida brasiliensis mexicana) keywords: bats; exposure; island; population; prevalence; rabies; rabv; rvna; samples; seropositivity; species; study; trinidad; virus cache: cord-004510-cbutpjre.txt plain text: cord-004510-cbutpjre.txt item: #9 of 99 id: cord-005012-bgo0uwob author: Hiller, Thomas title: Host Biology and Anthropogenic Factors Affect Hepadnavirus Infection in a Neotropical Bat date: 2018-12-18 words: 5469 flesch: 38 summary: Drexler et al. (2013) showed that TBHBV surface proteins allowed specific viral binding and in vitro entry into human hepatocytes via the human HBV high-affinity receptor NTCP (natrium taurocholate co-transporting protein), providing an interesting viral model organism. Following protocols described in Drexler et al. (2013) , purified samples were screened for hepadnavirus DNA using a broadly reactive nested-PCR leading to amplification of a 354 bp fragment encoding the surface and polymerase proteins. keywords: bats; bilobatum; cover; drexler; et al; forest; hepatitis; human; infection; model; roosting; tbhbv; virus cache: cord-005012-bgo0uwob.txt plain text: cord-005012-bgo0uwob.txt item: #10 of 99 id: cord-006502-6ajms947 author: Cheng, Chak Kwong title: Perivascular Adipose Tissue: the Sixth Man of the Cardiovascular System date: 2018-08-31 words: 12925 flesch: 29 summary: Hence, it is postulated that sympathetic innervation in PVAT modulates PVAT mediator release and integral for normal vascular function as well as pathophysiology and vice versa. Several other mouse models with ablation of adipose tissue might be potentially suitable for PVAT study, including those of either inborn or inducible adipose deletion [51] . keywords: adipocytes; adiponectin; adipose; adipose tissue; artery; cells; contractile; effect; endothelial; fat; innervation; leptin; mice; nerves; obesity; pvat; rat; regulation; role; sensory; studies; study; system; tissue; vascular cache: cord-006502-6ajms947.txt plain text: cord-006502-6ajms947.txt item: #11 of 99 id: cord-010307-sxh5mq1q author: MILNE, D. J. title: Structure and environmental relationships of insectivorous bat assemblages in tropical Australian savannas date: 2005-11-23 words: 6439 flesch: 49 summary: At each site we used a range of sampling techniques to maximize the likelihood of obtaining a full inventory of bat species (Kuenzi & Morrison 1998; Murray et al . 1999; The occurrence of bat species within the derived groups and habitat types is summarized in Table 2 and the geographical distribution of sites (classified according to group) is shown in Fig. keywords: analysis; assemblages; australia; bat; bats; composition; end; group; habitat; mean; north; sampling; sites; species; variables cache: cord-010307-sxh5mq1q.txt plain text: cord-010307-sxh5mq1q.txt item: #12 of 99 id: cord-017407-nc9cyu2u author: Mehlhorn, Heinz title: Introduction: The World of Bats date: 2013-09-03 words: 1103 flesch: 56 summary: Especially Drosten's laboratory and the microbiological institute of the University of Hong Kong showed that numerous bat species were carriers of the human-associated Corona virus (SARS-CoV). Thus, their hidden way of life caused fear, especially in those cases, when many bats fly simultaneously around houses or around heads of persons, since they live together in groups of often more than 100-150 animals hiding themselves during daytime in the treetops (e.g. plant eating flying foxes e.g. in Australia) or in tunnels of railways, galleries of closed mines, in old, rottening empty buildings on practically all continents except for Antarctica. keywords: bats; body; species cache: cord-017407-nc9cyu2u.txt plain text: cord-017407-nc9cyu2u.txt item: #13 of 99 id: cord-017785-zwnkrs23 author: Baker, Michelle L. title: Mammalia: Chiroptera: Immunology of Bats date: 2018-03-10 words: 9431 flesch: 34 summary: The little brown bat, M. Lucifugus, displays a highly diverse VH, DH and JH repertoire but little evidence of somatic hypermutation Bats as 'special' reservoirs for emerging zoonotic pathogens The two suborders of chiropterans have the canonical heavy-chain immunoglobulin (Ig) gene repertoire of eutherian mammals The immunoglobulin genes of bats Dichotomy of lymphocyte population and cell mediated immune responses in a fruit bat, Pteropus giganteus Antibody-mediated immune response in the bat, Pteropus giganteus Analysis of suppressor factor in delayed immune responses of a bat, Pteropus giganteus IFN[beta]-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage Tacaribe virus causes fatal infection of an ostensible host, the Jamaican fruit bat Molecular characterisation of toll-like receptors in the black flying fox Pteropus alecto Molecular characterisation of RIGIlike helicases in the black flying fox, Pteropus alecto Characterisation of novel microR-NAs in the black flying fox (Pteropus alecto) by deep sequencing ) Establishment, immortalisation and characterisation of pteropid bat cell lines Effects of aerosolized rabies virus exposure on bats and mice The IFN response in bat cells consists of canonical and non-canonical ISGs with unique temporal expression kinetics Duration of maternal antibodies against canine distemper virus and Hendra virus in Pteropid bats DNA-PK is a DNA sensor for IRF-3-dependent innate immunity The natural history of Hendra and Nipah viruses The white-nose syndrome transcriptome: activation of anti-fungal host responses in wing tissue of hibernating little brown myotis Evolution and antiviral specificities of interferon-induced Mx proteins of bats against ebola, influenza, and other RNA viruses Transcriptomic signatures of Tacaribe virus-infected Jamaican fruit bats Pathogenesis of experimental histoplasmosis in the bat, Artibeus lituratus Co-evolution of MHC class I and variable NK cell receptors in placental mammals Isolation of Hendra virus from pteropid bats: a natural reservoir of Hendra virus Pteropid bats are confirmed as the reservoir hosts of Henipaviruses: a comprehensive experimental study of virus transmission Evolution and survival of marine carnivores did not require a diversity of killer cell Ig-like receptors or Ly49 NK cell receptors Immune response in Chiroptera to bacteriophage øX174 Studies on the immune capabilities of Chiroptera Positive selection of the bat interferon alpha gene family Anti-lyssaviral activity of interferon κ and ω from the Serotine bat, Eptesicus serotinus Follicular dendritic cells: dynamic antigen libraries Widespread bat white-nose syndrome fungus, northeastern China Molecular cloning and sequencing of the cDNAs encoding the bat interleukin (IL)-2, IL-4, IL-6, IL-10, IL-12p40, and tumor necrosis factor-alpha Molecular cloning and expression analysis of bat toll-like receptors 3, 7 and 9 Cloning, expression and antiviral activity of IFNγ from the Australian fruit bat, Pteropus alecto Dynamics of genome size evolution in birds and mammals Comparative genomics of natural killer cell receptor gene clusters Chiropteran types I and II interferon genes inferred from genome sequencing traces by a statistical gene-family assembler Innate immune responses of bat and human cells to Filoviruses: commonalities and distinctions Resistance in persisting bat populations after white-nose syndrome invasion Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats Phylogenomic analyses of bat subordinal relationships based on transcriptome data Fruit bats as reservoirs of Ebola virus Cloning and sequence analysis of Peromyscus yucatanicus (Rodentia) Th1 (IL-12p35, IFN-γ and TNF) and Th2 (IL-4, IL-10 and TGF-β) cytokines The morphology of the intestine of the insectivorous horseshoe bat (Rhinolophus hildebrandti, Peters): a scanning electron and light microscopic study Pathogenesis studies with Australian bat lyssavirus in grey-headed flying foxes (Pteropus poliocephalus) Immune responses in bats following intranasal infection with histoplasma capsulatum Cell-mediated immunity in two species of bats Role of immunoglobulin classes in experimental histoplasmosis in bats Pathology in euthermic bats with white nose syndrome suggests a natural manifestation of immune reconstitution inflammatory syndrome Experimental Nipah virus infection in Pteropid bats (Pteropus poliocephalus) Specific alterations in complement protein activity of little Brown Myotis (Myotis lucifugus) hibernating in whitenose syndrome affected sites Hibernating little Brown Myotis (Myotis lucifugus) show variable immunological responses to white-nose syndrome Bats and zoonotic viruses: can we confidently link bats with emerging deadly viruses? Evolution and comparative analysis of the bat MHC-I region Insights into the ancestral organisation of the mammalian MHC class II region from the genome of the pteropid bat, Pteropus alecto Induction and sequencing of Rousette bat interferon α and β genes Ontogenetic and anatomic variation in mineralization of the wing skeleton of the Mexican free-tailed bat, Tadarida brasiliensis The immune gene repertoire of an important viral reservoir, the Australian black flying fox Phytohaemagglutinin mediated activation of bat (Pteropus giganteus) lymphocytes Virological and serological findings in Rousettus aegyp-tiacus experimentally inoculated with Vero cells-adapted Hogan strain of Marburg virus Activation of innate immune-response genes in little Brown bats (Myotis lucifugus) infected with the fungus Pseudogymnoascus destructans Interferon-inducible antiviral effectors Analysis of immunocompetent cells in the bat, Pteropus giganteus: isolation and scanning electron microscopic characterization Immunology of bats and their viruses: challenges and opportunities Immunological control of viral infections in bats and the emergence of viruses highly pathogenic to humans Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats Egyptian rousette bats maintain long-term protective immunity against Marburg virus infection despite diminished antibody levels The evolution of the natural killer complex; a comparison between mammals using new high-quality genome assemblies and targeted annotation Transcriptome sequencing and annotation for the Jamaican fruit bat (Artibeus jamaicensi) Mammal species of the world: a taxonomic and geographic reference Persistent infection in bats and bat cell cultures with Japanese encephalitis virus Histological and histochemical analysis of the gastrointestinal tract of the common pipistrelle bat (Pipistrellus Pipistrellus) Studies of arthropod-borne virus infections in Chiroptera Immunological relationship between the mother and the fetus Geographical distribution of genetic polymorphism of the pathogen Histoplasma capsulatum isolated from infected bats, captured in a central zone of Mexico Molecular evidence regarding the origin of echolocation and flight in bats A molecular phylogeny for bats illuminates biogeography and the fossil record Phylogeny, genes, and hearing: implications for the evolution of echolocation in bats Bat biology, genomes, and the Bat1K project: to generate chromosome-level genomes for all living bat species Isolation of genetically diverse Marburg viruses from Egyptian fruit bats Phylogenomic analyses elucidate the evolutionary relationships of bats Histological assessment of cellular immune response to the phytohemagglutinin skin test in Brazilian free-tailed bats (Tadarida brasiliensis) Host immunity to repeated rabies virus infection in big brown bats Human follicular dendritic cells: function, origin and development Interferon production and signaling pathways are antagonized during Henipavirus infection of fruit bat cell lines Interferon signaling remains functional during Henipavirus infection of human cell lines Mass extinctions, biodiversity and mitochondrial function: are bats 'special' as reservoirs for emerging viruses? Detection of specific antibody responses to vaccination in variable flying foxes (Pteropus hypomelanus) Transmission studies of Hendra virus (equine morbilli-virus) in fruit bats, horses and cats Experimental Hendra virus infection in pregnant Guinea-pigs and fruit bats Purification and characterisation of immunoglobulins from the Australian black flying fox (Pteropus alecto) using anti-fab affinity chromatography reveals the low abundance of IgA Proteomics informed by transcriptomics reveals Hendra virus sensitizes bat cells to TRAIL mediated apoptosis Characterization of the antigen processing machinery and endogenous peptide presentation of a bat MHC class I molecule Comparative transcriptomics highlights the role of the AP1 transcription factor in the host response to Ebolavirus Nipah virus infection in bats (order Chiroptera) in peninsular Malaysia Comparative analysis of bat genomes provides insight into the evolution of flight and immunity IFNAR2-dependent gene expression profile induced by IFN-α in Pteropus alecto bat cells and impact of IFNAR2 knockout on virus infection Type III IFNs in pteropid bats: differential expression patterns provide evidence for distinct roles in antiviral immunity Type III IFN receptor expression and functional characterisation in the Pteropid bat, Pteropus alecto Bat Mx1 and Oas1, but not Pkr are highly induced by bat interferon and viral infection IRF7 in the Australian black flying fox, Pteropus alecto: evidence for a unique expression pattern and functional conservation Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats Unlocking bat immunology: establishment of Pteropus alecto bone marrow-derived dendritic cells and macrophages White-nose syndrome without borders: Pseudogymnoascus destructans infection tolerated in Europe and Palearctic Asia but not in keywords: antibodies; antibody; bats; cells; et al; flying; fox; genes; ifn; infection; mammals; pteropid; pteropus; responses; species; studies; virus; viruses cache: cord-017785-zwnkrs23.txt plain text: cord-017785-zwnkrs23.txt item: #14 of 99 id: cord-018821-e9oxvgar author: Webber, Quinn M. R. title: Sociality, Parasites, and Pathogens in Bats date: 2016-04-27 words: 10936 flesch: 24 summary: Constructing epidemiological models from empirical data undoubtedly improves inference for predicting epidemic outcomes, but as yet there are no studies that quantify real-world relationships between the social behavior of bat hosts and their parasites to test predictions of epidemiological models (Table 5 .3). Transmission of bacterial or viral pathogens via ectoparasite vectors among bat hosts could be influenced by sociality, especially for highly gregarious females at maternity colonies. keywords: bats; behavior; colonies; disease; dynamics; e.g.; et al; host; individuals; infection; network; parasite; pathogen; population; sociality; species; studies; transmission cache: cord-018821-e9oxvgar.txt plain text: cord-018821-e9oxvgar.txt item: #15 of 99 id: cord-021152-6znmkvy9 author: Montecino-Latorre, Diego title: Reproduction of East-African bats may guide risk mitigation for coronavirus spillover date: 2020-02-07 words: 8069 flesch: 44 summary: Because CoVs are found in bat species that have adapted to be in close contact with humans, such as the straw-colored fruit bat (Eidolon helvum) and the Brazilian free-tailed bat (Tadarida brasiliensis [44, 45] ), high contact bat-human interfaces currently exist around the world. Therefore, assessment of the CoV dynamics in a broader range of bat species that show different life history traits, as well as in diverse geographic and ecological circumstances, could be extremely useful. keywords: age; bats; coronavirus; cov; covs; data; detection; human; infection; period; risk; sampling; season; shedding; species; spillover; viruses cache: cord-021152-6znmkvy9.txt plain text: cord-021152-6znmkvy9.txt item: #16 of 99 id: cord-021805-2j07zw6q author: Epstein, Jonathan H. title: Emerging Diseases in Bats date: 2018-09-28 words: 4161 flesch: 42 summary: Also, having a library of sequences from all bat CoVs, filoviruses, or Risk factors for human disease emergence Zoonoses 3 Prediction and prevention of the next pandemic zoonosis Anthropogenic change, biodiversity loss, and a new agenda for emerging diseases Origins of major human infectious diseases Anthropogenic environmental change and the emergence of infectious diseases in wildlife Host and viral traits predict zoonotic spillover from mammals Immunology of bats and their viruses: challenges and opportunities Anthropogenic epidemics: the ecology of bat borne viruses and our role in their emergence A molecular phylogeny for bats illuminates biogeography and the fossil record Filoviruses in bats: current knowledge and future directions Roosting behaviour and habitat selection of Pteropus giganteus reveal potential links to Nipah virus epidemiology Walker's bats of the world Microchiropteran bats: global status survey and conservation action plan Economic importance of bats in agriculture Flying foxes (Chiroptera, Pteropodidae): threatened animals of key ecological and economic importance A review of the global conservation status of bats Viral discovery as a tool for pandemic preparedness Nipah virus: a recently emergent deadly paramyxovirus Agricultural intensification, priming for persistence and the emergence of Nipah virus: a lethal bat-borne zoonosis Ecological aspects of Hendra Virus Risk factors for Nipah virus infection among pteropid bats, peninsular Malaysia, Emerg Infect Dis coronavirus-like virus in palm civets at an animal market and on farms Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia Middle East Respiratory Syndrome Coronavirus in Bats, Saudi Arabia Global patterns in coronavirus diversity Dromedary camels and the transmission of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Predictors of MERS-CoV infection: a large case control study of patients presenting with ILI at a MERS-CoV referral hospital in Saudi Arabia Middle East Respiratory Syndrome Coronavirus superspreading event involving 81 persons Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS Porcine epidemic diarrhea virus: an emerging and reemerging epizootic swine virus Bat Coronavirus in Brazil related to Appalachian Ridge and porcine epidemic diarrhea viruses Group C Betacoronavirus in Bat Guano Fertilizer Marburgvirus resurgence in Kitaka Mine bat population after extermination attempts The Global Virome Project Seasonal pulses of Marburg virus circulation in juvenile Rousettus aegyptiacus bats coincide with periods of increased risk of human infection Modelling filovirus maintenance in nature by experimental transmission of Marburg virus between Egyptian rousette bats Fruit bats as reservoirs of Ebola virus Molecular evidence of Ebola Reston virus infection in Philippine bats Ebola virus antibodies in fruit bats Genetically diverse filoviruses in Rousettus and Eonycteris spp Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats Oral shedding of Marburg virus in experimentally infected Egyptian fruit bats (Rousettus aegyptiacus) Human coronaviruses: what do they cause? Data are mounting to support bats as important reservoirs compared with other mammals, and large-scale surveillance efforts like PREDICT and the recently launched Global Virome Project, a 10-year effort to identify the majority of viruses in key wildlife species in emerging disease hot spots, 73 will shed more light on the total diversity of viruses in bat species and the types of human-animal interfaces that exist in different geographic and cultural contexts. keywords: animal; bats; cov; ebola; human; infection; niv; species; virus; viruses cache: cord-021805-2j07zw6q.txt plain text: cord-021805-2j07zw6q.txt item: #17 of 99 id: cord-102977-yci9kq6x author: Liu, Haiming title: GHSR-1a is not Required for Ghrelin’s Anti-inflammatory and Fat-sparing Effects in Cancer Cachexia date: 2019-12-06 words: 4894 flesch: 46 summary: Given that there are no treatments for cancer cachexia and that several clinical trials targeting this pathway have failed to 191 meet their primary endpoints (Garcia et al., 2015 , Temel, Abernethy et al., 2016 , there is a pressing 192 need to improve our understanding of the mechanisms of action of ghrelin in this setting. Weight loss and survival rates are correlated with IL-6 levels in cancer patients (Garcia et al., 2005, 202 Moses, Maingay et al., 2009 , Scott, McMillan et al., 1996 . keywords: bat; cachexia; cancer; et al; ghrelin; inflammation; tissue; tumor; wat cache: cord-102977-yci9kq6x.txt plain text: cord-102977-yci9kq6x.txt item: #18 of 99 id: cord-103460-5thh6syt author: Carlson, Colin J. title: Climate change will drive novel cross-species viral transmission date: 2020-07-14 words: 1439 flesch: 44 summary: Moving forward, the rapid range shifts already observed 532 in many bat species (see main text) could provide an empirical reference point to fit a new allo-533 metric scaling curve (after standardizing those results for the studies' many different method-534 ologies). Counter to expectations, holding warming under 2°C within the century does not reduce new viral sharing, due to greater range expansions—highlighting the need to invest in surveillance even in a low-warming future. keywords: bats; climate; dispersal; sharing; species cache: cord-103460-5thh6syt.txt plain text: cord-103460-5thh6syt.txt item: #19 of 99 id: cord-254543-gxwtqqdu author: Suwannarong, Kanokwan title: Bat consumption in Thailand date: 2016-01-22 words: 2836 flesch: 58 summary: Exposure to bats, bat guano, and bat excreta through bat consumption puts people at risk of direct contact with bat-borne viruses (14, 17) . Beyond bushmeat: animal contact, injury, and zoonotic disease risk in Western Uganda Global trends in emerging infectious diseases Bats as a continuing source of emerging infections in humans A comparison of bats and rodents as reservoirs of zoonotic viruses: are bats special? Bats and emerging zoonoses: henipaviruses and SARS Fruit bats as reservoirs of Ebola virus Long-term survival of an urban fruit bat seropositive for Ebola and Lagos bat viruses Adaptive evolution of bat dipeptidyl peptidase 4 (dpp4): implications for the origin and emergence of Middle East respiratory syndrome coronavirus Characteristics and risk perceptions of Ghanaians potentially exposed to bat-borne zoonoses through bushmeat Old world phytophagous bats (Megachiroptera) and their food plants: a survey Diet of wrinkle-lipped free-tailed bat (Tadarida plicata Buchannan, 1800) in central Thailand: insectivorous bats potentially act as biological pest control agents Investigating the role of bats in emerging zoonoses: balancing ecology, conservation and public health interests. keywords: bats; consumption; guano; miners; respondents; risk; study cache: cord-254543-gxwtqqdu.txt plain text: cord-254543-gxwtqqdu.txt item: #20 of 99 id: cord-254713-ghcwfcx2 author: Razanajatovo, Norosoa H title: Detection of new genetic variants of Betacoronaviruses in Endemic Frugivorous Bats of Madagascar date: 2015-03-12 words: 4165 flesch: 44 summary: Some authors have reported the detection of bat CoVs from mainland Africa Thus, further molecular epidemiology studies would be required to fully understand the dispersal potential of CoVs amongst Malagasy bats species. keywords: bats; coronaviruses; covs; human; madagascar; malagasy; min; species; study cache: cord-254713-ghcwfcx2.txt plain text: cord-254713-ghcwfcx2.txt item: #21 of 99 id: cord-255137-utg8k7qs author: Yinda, Claude Kwe title: Gut Virome Analysis of Cameroonians Reveals High Diversity of Enteric Viruses, Including Potential Interspecies Transmitted Viruses date: 2019-01-23 words: 9795 flesch: 40 summary: VIRSorter_NODE_210_length_3873_cov_4_79189-cat_1 VIRSorter_NODE_388_length_2881_cov_7_17939-cat_1 VIRSorter_NODE_5_length_42493_cov_21_423-circular-cat_1 VIRSorter_NODE_8_length_45832_cov_51_2672-cat_1 VIRSorter_NODE_4_length_43684_cov_82_015-circular-cat_2 VIRSorter_NODE_15_length_28369_cov_37_8786-cat_2 VIRSorter_NODE_16_length_34096_cov_10_5837-cat_1 VIRSorter_NODE_7_length_23030_cov_44_5743-cat_2 VIRSorter_NODE_4_length_46080_cov_143_372-circular-cat_1 VIRSorter_NODE_154_length_5846_cov_32_8156-cat_2 VIRSorter_NODE_2_length_40986_cov_83_5436-cat_2 VIRSorter_NODE_14_length_28627_cov_424_601-cat_2 VIRSorter_NODE_130_length_7398_cov_6_88034-cat_2 VIRSorter_NODE_911_length_1516_cov_2_82279-cat_2 VIRSorter_NODE_60_length_9439_cov_32_4934-cat_1 VIRSorter_NODE_98_length_5449_cov_11_7885-cat_1 VIRSorter_NODE_193_length_2388_cov_2_87797-cat_2 VIRSorter_NODE_25_length_14198_cov_12_3353-cat_2 VIRSorter_NODE_83_length_6779_cov_23_1462-cat_1 VIRSorter_NODE_37_length_8496_cov_10_6883-cat_1 VIRSorter_NODE_97_length_6417_cov_22_439-cat_2 VIRSorter_NODE_20_length_3093_cov_15_1522-cat_1 VIRSorter_NODE_794_length_2121_cov_3_72505-cat_2 VIRSorter_NODE_510_length_2453_cov_9_21212-cat_2 VIRSorter_NODE_11_length_24212_cov_31_2924-cat_1 VIRSorter_NODE_16_length_17400_cov_20_1101-cat_2 VIRSorter_NODE_1_length_45933_cov_26_6238-cat_1 VIRSorter_NODE_4_length_46625_cov_133_007-circular-cat_1 VIRSorter_NODE_52_length_9386_cov_11_0833-cat_2 VIRSorter_NODE_229_length_1757_cov_2_47857-cat_2 VIRSorter_NODE_11_length_20025_cov_19_5373-cat_1 VIRSorter_NODE_22_length_11775_cov_21_2965-cat_1 VIRSorter_NODE_107_length_7429_cov_59_5487-cat_2 VIRSorter_NODE_5_length_61314_cov_65_5801-cat_2 VIRSorter_NODE_8_length_28098_cov_49_3527-cat_2 VIRSorter_NODE_59_length_6288_cov_49_065-cat_1 VIRSorter_NODE_6_length_39977_cov_34_3534-cat_2 VIRSorter_NODE_145_length_6050_cov_14_9503-cat_2 VIRSorter_NODE_3_length_55511_cov_174_071-cat_2 VIRSorter_NODE_512_length_1992_cov_5_2329-cat_1 VIRSorter_NODE_43_length_9047_cov_24_7407-cat_1 VIRSorter_NODE_7_length_27940_cov_25_4928-cat_2 VIRSorter_NODE_30_length_20704_cov_18_18-cat_2 VIRSorter_NODE_284_length_3092_cov_4_56783-cat_2 VIRSorter_NODE_21_length_10227_cov_70_6216_ID_1234280-cat_1 VIRSorter_NODE_244_length_3185_cov_5_53925-cat_1 VIRSorter_NODE_9_length_14015_cov_52_0782-cat_2 VIRSorter_NODE_483_length_3784_cov_3_74777-cat_2 VIRSorter_NODE_163_length_1997_cov_6_07969-cat_1 VIRSorter_NODE_73_length_9441_cov_6_50694-cat_1 VIRSorter_NODE_391_length_2005_cov_13_5311-cat_2 VIRSorter_NODE_48_length_4545_cov_11_4716-cat_2 VIRSorter_NODE_274_length_2499_cov_6_84104-cat_1 VIRSorter_NODE_5_length_45101_cov_33_3939-cat_2 VIRSorter_NODE_84_length_5772_cov_5_66831-cat_1 VIRSorter_NODE_228_length_3330_cov_15_3372-cat_1 VIRSorter_NODE_38_length_6638_cov_33_8407-cat_2 VIRSorter_NODE_110_length_3327_cov_40_0329_ID_1235347-cat_2 VIRSorter_NODE_292_length_3977_cov_5_20205-cat_2 VIRSorter_NODE_73_length_4137_cov_29_2744-cat_2 VIRSorter_NODE_109_length_3682_cov_5_79945-cat_2 VIRSorter_NODE_2060_length_1098_cov_2_56024-cat_2 VIRSorter_NODE_186_length_5287_cov_24_3374-cat_2 VIRSorter_NODE_128_length_4404_cov_8_8202-cat_2 VIRSorter_NODE_8_length_40727_cov_52_8639-circular-cat_1 VIRSorter_NODE_241_length_2048_cov_3_82192-cat_2 VIRSorter_NODE_566_length_1570_cov_4_87877-cat_1 VIRSorter_NODE_236_length_2071_cov_8_333-cat_2 VIRSorter_NODE_21_length_8643_cov_7_23897-cat_1 Halocynthia~phage~JM-2012 Bacillus~phage~NotTheCreek Bacillus~phage~Belinda Listeria~phage~LP-083-2 VIRSorter_NODE_12_length_23882_cov_20_202-cat_2 Bacillus~phage~W.Ph. Enterococcus~phage~EFLK1 VIRSorter_NODE_421_length_3484_cov_2_88788-cat_2 VIRSorter_NODE_51_length_6073_cov_24_308-cat_2 VIRSorter_NODE_126_length_4338_cov_7_34968-cat_2 VIRSorter_NODE_743_length_2937_cov_5_76678-cat_2 VIRSorter_NODE_572_length_1258_cov_4_2989-cat_2 VIRSorter_NODE_511_length_1714_cov_9_19609-cat_2 VIRSorter_NODE_105_length_2295_cov_5_80162_ID_209_GC022959_GC022959-cat_2 VIRSorter_NODE_351_length_1653_cov_3_89784-cat_2 VIRSorter_NODE_62_length_4317_cov_5_92123_GC022960_GC022960-cat_2 VIRSorter_NODE_70_length_5230_cov_7_68756-cat_1 VIRSorter_NODE_59_length_5445_cov_7_07004-cat_2 VIRSorter_NODE_151_length_2931_cov_21_0263-cat_2 VIRSorter_NODE_87_length_2972_cov_3_15406-cat_2 VIRSorter_NODE_52_length_12117_cov_12_12-cat_2 VIRSorter_NODE_11_length_18974_cov_17_7842-cat_2 VIRSorter_NODE_2774_length_1414_cov_2_55497-cat_2 VIRSorter_NODE_250_length_2007_cov_4_84663-cat_2 VIRSorter_NODE_92_length_4947_cov_8_09199-cat_2 VIRSorter_NODE_1203_length_1540_cov_6_38619-cat_2 VIRSorter_NODE_46_length_7537_cov_11_1706-cat_2 VIRSorter_NODE_2982_length_1113_cov_2_02703-cat_2 VIRSorter_NODE_150_length_2967_cov_3_60415-cat_2 VIRSorter_NODE_856_length_1683_cov_5_93275-cat_2 VIRSorter_NODE_297_length_2600_cov_4_91082-cat_2 VIRSorter_NODE_891_length_1502_cov_2_53754-cat_2 VIRSorter_NODE_234_length_5884_cov_5_88807-cat_2 VIRSorter_NODE_142_length_4144_cov_6_25424-cat_2 VIRSorter_NODE_1046_length_1299_cov_4_62684-cat_2 VIRSorter_NODE_150_length_4016_cov_26_916-cat_1 VIRSorter_NODE_29_length_15514_cov_39_9365-cat_2 VIRSorter_NODE_315_length_2377_cov_6_79043-cat_2 VIRSorter_NODE_53_length_6164_cov_14_1464-cat_2 VIRSorter_NODE_324_length_2523_cov_8_04415-cat_2 VIRSorter_NODE_234_length_3252_cov_10_1729-cat_2 VIRSorter_NODE_14_length_18167_cov_39_9557-cat_2 VIRSorter_NODE_240_length_2054_cov_3_92817-cat_2 VIRSorter_NODE_846_length_2391_cov_4_03933-cat_2 VIRSorter_NODE_476_length_1954_cov_5_94406_GC021836_GC021836-cat_2 VIRSorter_NODE_74_length_3590_cov_49_2966-cat_2 VIRSorter_NODE_568_length_1984_cov_4_76403-cat_2 VIRSorter_NODE_13_length_17922_cov_52_6305-cat_1 VIRSorter_NODE_433_length_2253_cov_3_42233-cat_2 VIRSorter_NODE_335_length_2021_cov_4_10391_GC021842_GC021842-cat_2 VIRSorter_NODE_138_length_3112_cov_4_00791-cat_2 VIRSorter_NODE_1458_length_1041_cov_2_11722_GC021830_GC021830-cat_2 VIRSorter_NODE_42_length_4096_cov_4_64369-cat_1 VIRSorter_NODE_76_length_2941_cov_3_10859_ID_151_GC022959_GC022959-cat_2 VIRSorter_NODE_590_length_1526_cov_7_29262_GC021830_GC021830-cat_2 VIRSorter_NODE_271_length_4659_cov_16_1942-cat_2 VIRSorter_NODE_54_length_4664_cov_9_37127-cat_2 VIRSorter_NODE_407_length_2846_cov_138_023_GC021836_GC021836-cat_1 VIRSorter_NODE_1721_length_1996_cov_5_9359-cat_2 VIRSorter_NODE_428_length_2323_cov_3_73776-cat_2 VIRSorter_NODE_356_length_2384_cov_8_9935-cat_2 VIRSorter_NODE_332_length_2175_cov_10_2507-cat_2 VIRSorter_NODE_1147_length_1321_cov_3_40756-cat_1 VIRSorter_NODE_100_length_4424_cov_7_35335-cat_2 VIRSorter_NODE_1703_length_1463_cov_2_22872-cat_2 VIRSorter_NODE_366_length_3576_cov_8_32009_GC021836_GC021836-cat_2 VIRSorter_NODE_725_length_1855_cov_10_6147-cat_2 VIRSorter_NODE_1238_length_1327_cov_2_0664-cat_2 VIRSorter_NODE_672_length_1295_cov_4_3514-cat_2 VIRSorter_NODE_79_length_6354_cov_62_2409-cat_2 VIRSorter_NODE_78_length_6260_cov_45_9512-cat_2 keywords: age; analysis; bats; cameroon; cameroonian; cat_2; children; contact; fig; gastroenteritis; genomes; human; identity; novel; phage; pools; reads; region; samples; species; strains; study; viruses cache: cord-255137-utg8k7qs.txt plain text: cord-255137-utg8k7qs.txt item: #22 of 99 id: cord-256370-cz88t29n author: Jansen van Vuren, Petrus title: Isolation of a Novel Fusogenic Orthoreovirus from Eucampsipoda africana Bat Flies in South Africa date: 2016-02-29 words: 5541 flesch: 43 summary: 1 63.0 54.3 53.9 63.1 63.8 63.3 63.6 64.7 MAHLV replicated efficiently in Vero cell culture, with the inoculum containing a high dose of virus (10 5 TCID 50 /mL) leading to rapid monolayer destruction after inoculation, with a peak in virus RNA (measured by real-time RT-PCR) by day 7, followed by a decrease on day 13. The ectoparasite pool homogenate used for virus isolation was used as DNA source for phylogenetic confirmation of species. keywords: acid; amino; bat; bats; cells; culture; isolation; mahlv; orthoreovirus; protein; sequence; species; vero; virus; viruses cache: cord-256370-cz88t29n.txt plain text: cord-256370-cz88t29n.txt item: #23 of 99 id: cord-256452-77xij0fc author: Allen, Louise C. title: Roosting ecology and variation in adaptive and innate immune system function in the Brazilian free-tailed bat (Tadarida brasiliensis) date: 2008-11-11 words: 5437 flesch: 40 summary: However, few studies have examined immune responses in bats, and even fewer have evaluated these responses in an ecological context. (2001) found that T cell mediated immune response in fledglings of the Magellanic penguin (Spheniscus magellanicus) was negatively correlated with colony size, whereas Møller et al. keywords: ability; bats; blood; cave; cell; colony; immune; response; roost; type cache: cord-256452-77xij0fc.txt plain text: cord-256452-77xij0fc.txt item: #24 of 99 id: cord-257321-l1swyr6g author: Chen, Lihong title: DRodVir: A resource for exploring the virome diversity in rodents date: 2017-05-20 words: 3250 flesch: 38 summary: Database (Oxford) MUSCLE: multiple sequence alignment with high accuracy and high throughput Rodent-borne emerging viral zoonosis: hemorrhagic fevers and hantavirus infections in South America Detection of zoonotic pathogens and characterization of novel viruses carried by commensal Rattus norvegicus Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor Rodent-borne hemorrhagic fevers: under-recognized, widely spread and preventableepidemiology, diagnostics and treatment Rodent phylogeny and a timescale for the evolution of Glires: evidence from an extensive taxon sampling using three nuclear genes Global trends in emerging infectious diseases Wildlife as source of zoonotic infections A comparison of bats and rodents as reservoirs of zoonotic viruses: are bats special? ViralZone: recent updates to the virus knowledge resource Rodent-borne diseases and their risks for public health Impacts of the cretaceous terrestrial revolution and KPg extinction on mammal diversification Potential influence of climate change on vector-borne and zoonotic diseases: a review and proposed research plan Replication and shedding of MERS-CoV in Jamaican fruit bats (Artibeus jamaicensis) Yersinia pestiseetiologic agent of plague FastTree 2eapproximately maximumlikelihood trees for large alignments Bats and their virome: an important source of emerging viruses capable of infecting humans jsPhyloSVG: a javascript library for visualizing interactive and vector-based phylogenetic trees on the web Rodent Societies: an Ecological and Evolutionary Perspective Bats as a continuing source of emerging infections in humans To facilitate online data analysis, two visualization tools are integrated into the result table: i) a statistical pie chart is available with a single click on the column title of virus family, rodent species/family, sample type and sampling country (Fig. 2B) ; ii) a global map with indicative markers is provided for the column of sampling country to better illustrate the geographic distribution of the rodent-associated viruses (http://www.mgc.ac. cn/cgi-bin/DRodVir/main.cgi?func¼map). keywords: bats; database; rodents; species; virome; viruses cache: cord-257321-l1swyr6g.txt plain text: cord-257321-l1swyr6g.txt item: #25 of 99 id: cord-258160-v08cs51n author: Wang, Lin-Fa title: Review of Bats and SARS date: 2006-12-17 words: 3797 flesch: 39 summary: Severe acute respiratory syndrome Laboratory diagnosis of four recent sporadic cases of communityacquired SARS Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human Characterization of a novel coronavirus associated with severe acute respiratory syndrome The genome sequence of the SARS-associated coronavirus A novel coronavirus associated with severe acute respiratory syndrome Epidemiologic clues to SARS origin in China Prevalence of IgG antibody to SARS-associated coronavirus in animal traders Isolation and characterization of viruses related to the SARS coronavirus from animals in Southern China Molecular evolution of the SARS coronavirus during the course of the SARS epidemic in China Civets are equally susceptible to experimental infection by two different severe acute respiratory syndrome coronavirus isolates Koch's postulates fulfilled for SARS virus An animal model of SARS produced by infection of Macaca mulatta with SARS coronavirus Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque Mucosal immunisation of African green monkeys (Cercopithecus aethiops) with an attenuated parainfluenza virus expressing the SARS coronavirus spike protein for the prevention of SARS Virology: SARS virus infection of cats and ferrets Severe acute respiratory syndrome coronavirus infection of golden Syrian hamsters Pathology of guinea pigs experimentally infected with a novel reovirus and coronavirus isolated from SARS patients Aged BALB/c mice as a model for increased severity of severe acute respiratory syndrome in elderly humans Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice SARS-associated coronavirus transmitted from human to pig Susceptibility of pigs and chickens to SARS coronavirus Possible role of an animal vector in the SARS outbreak at Amoy Gardens Domestic poultry and SARS coronavirus, southern China SARS-CoV infection in a restaurant from palm civet Antibodies to SARS coronavirus in civets Molecular evolution analysis and geographic investigation of severe acute respiratory syndrome coronavirus-like virus in palm civets at an animal market and on farms Identification of a novel coronavirus in bats The ecology of wildlife diseases Bats are natural reservoirs of SARS-like coronaviruses Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats Molecular diversity of coronaviruses in bats Prevalence and genetic diversity of coronaviruses in bats from China Zoonotic viruses of wildlife: hither from yon Animal origins of the severe acute respiratory syndrome coronavirus: insight from ACE2-S-protein interactions Bats: important reservoir hosts of emerging viruses Emerging henipaviruses and flying foxes-conservation and management perspectives Emerging encephalitogenic viruses: lyssaviruses and henipaviruses transmitted by frugivorous bats European bat lyssaviruses: distribution, prevalence and implications for conservation Diseases of humans and their domestic mammals: pathogen characteristics, host range and the risk of emergence The work conducted by our multination collaborative team was jointly funded by a special For example, bat SARS-like-CoVs and another yet unknown coronavirus could coinfect an intermediate host, and the bat viruses would gain the ACE2 binding site in the S1 domain by recombination. keywords: bat; bats; coronaviruses; cov; covs; reservoir; sars; species cache: cord-258160-v08cs51n.txt plain text: cord-258160-v08cs51n.txt item: #26 of 99 id: cord-261547-8tfbhmzo author: Góes, Luiz Gustavo Bentim title: Genetic diversity of bats coronaviruses in the Atlantic Forest hotspot biome, Brazil date: 2016-07-26 words: 1973 flesch: 45 summary: Similar results were previously reported for a variety of bat CoVs and are taken as evidence of co-evolution of CoV genotypes and specific host genera (Drexler et al., 2014; Corman et al., 2013; Anthony et al., 2013) . Although it is not possible to calculate the risk of spill over events of Brazilian bats CoVs to humans, our results reinforce the need for expanded and continuing surveillance of CoVs in bat fauna, including those in the AFB regions of Brazil. keywords: bats; cov; covs; et al; species cache: cord-261547-8tfbhmzo.txt plain text: cord-261547-8tfbhmzo.txt item: #27 of 99 id: cord-262434-q4tk96tq author: Baker, Kate S. title: Poxviruses in Bats … so What? date: 2014-04-03 words: 3332 flesch: 32 summary: [40] [41] [42] and there is currently insufficient evidence available to determine what the zoonotic potential of bat poxviruses might be on this spectrum. However, given that no bat poxviruses identified to date are orthopoxviruses, and the little information available, it is clear that much more detail is needed before the potential threat of bat poxviruses to man can be commented on. keywords: bats; host; infections; novel; potential; poxviruses; range; species; zoonotic cache: cord-262434-q4tk96tq.txt plain text: cord-262434-q4tk96tq.txt item: #28 of 99 id: cord-262815-fg76s168 author: Anthony, S. J. title: Coronaviruses in bats from Mexico date: 2013-05-01 words: 4395 flesch: 48 summary: Prior to this study, very little was known about the diversity of CoVs in the neotropics, despite the high diversity of bat species found here (Wilson & Reeder, 2005) . Previous work has shown that bat diversity often reflects the level of disturbance for a given habitat, with lower diversity recorded in disturbed areas (Medellín et al., 2000) . keywords: bats; coronaviruses; covs; detection; diversity; et al; habitat; host; mexico; novel; species; viruses cache: cord-262815-fg76s168.txt plain text: cord-262815-fg76s168.txt item: #29 of 99 id: cord-265357-3f0xph0y author: Halczok, Tanja K. title: Evidence for genetic variation in Natterer’s bats (Myotis nattereri) across three regions in Germany but no evidence for co-variation with their associated astroviruses date: 2017-01-05 words: 6543 flesch: 42 summary: Associations between astrovirus and bat host genetic distances (both mitochondrial and nuclear) were first analyzed via a Mantel Test In comparison, for bat ectoparasites such as bat flies (Nycteribiidae) that are also transmitted both by direct body contact and indirectly through the bats' roosts, a more efficient transmission among different bat populations has been detected at swarming sites as compared to breeding colonies [29] . keywords: astrovirus; bat; bats; colonies; distance; host; nrw; population; regions; species; structure; viruses cache: cord-265357-3f0xph0y.txt plain text: cord-265357-3f0xph0y.txt item: #30 of 99 id: cord-268645-5op2m7pu author: Wu, Zhiqiang title: Deciphering the bat virome catalog to better understand the ecological diversity of bat viruses and the bat origin of emerging infectious diseases date: 2015-08-11 words: 5953 flesch: 40 summary: key: cord-268645-5op2m7pu authors: Wu, Zhiqiang; Yang, Li; Ren, Xianwen; He, Guimei; Zhang, Junpeng; Yang, Jian; Qian, Zhaohui; Dong, Jie; Sun, Lilian; Zhu, Yafang; Du, Jiang; Yang, Fan; Zhang, Shuyi; Jin, Qi title: Deciphering the bat virome catalog to better understand the ecological diversity of bat viruses and the bat origin of emerging infectious diseases date: 2015-08-11 journal: The ISME Journal DOI: 10.1038/ismej.2015.138 sha: doc_id: 268645 cord_uid: 5op2m7pu Studies have demonstrated that ~60%–80% of emerging infectious diseases (EIDs) in humans originated from wild life. In conclusion, the understanding of the viral community characteristics, genetics and ecological distribution of bat viruses could enable the rapid identification of novel viruses with variant genomes and could thus facilitate the tracing of EIDs in bats. keywords: bat; bats; covs; et al; figure; human; novel; reads; samples; sars; species; table; viruses cache: cord-268645-5op2m7pu.txt plain text: cord-268645-5op2m7pu.txt item: #31 of 99 id: cord-270143-muxrxvyo author: Markotter, Wanda title: Paramyxo- and Coronaviruses in Rwandan Bats date: 2019-07-02 words: 4903 flesch: 43 summary: Host gene sequences were subsequently compared to bat sequences available in the public domain (on the NCBI GenBank and BOLD databases), results were interpreted and compared with the respective morphological field identifications. In addition to morphological identification of bat species, we also did molecular confirmation of species identities, contributing to the known genetic database available for African bat species. keywords: africa; assay; bats; coronaviruses; host; paramyxoviruses; rna; rwanda; samples; sequences; species; usa; viruses cache: cord-270143-muxrxvyo.txt plain text: cord-270143-muxrxvyo.txt item: #32 of 99 id: cord-270335-8vqi9c68 author: Seifert, Stephanie N title: Rousettus aegyptiacus Bats Do Not Support Productive Nipah Virus Replication date: 2019-11-04 words: 3276 flesch: 40 summary: Bats: important reservoir hosts of emerging viruses Experimental inoculation of Egyptian rousette bats (Rousettus aegyptiacus) with viruses of the ebolavirus and marburgvirus genera Experimental inoculation of Egyptian fruit bats (Rousettus aegyptiacus) with ebola virus Establishment of fruit bat cells (Rousettus aegyptiacus) as a model system for the investigation of filoviral infection SARSlike coronavirus WIV1-CoV does not replicate in Egyptian fruit bats (Rousettus aegyptiacus) Membrane fusion tropism and heterotypic functional activities of the Nipah virus and Hendra virus envelope glycoproteins Undiscovered bat hosts of filoviruses Egyptian fruit bats are common in zoological settings because they are small, amenable to handling, and reproduce readily in captivity. keywords: bats; cell; efb; ephrin; fruit; infection; nipah; niv; pteropus; replication; virus cache: cord-270335-8vqi9c68.txt plain text: cord-270335-8vqi9c68.txt item: #33 of 99 id: cord-270803-jtv5jmkn author: Wang, Lin-Fa title: Mass extinctions, biodiversity and mitochondrial function: are bats ‘special’ as reservoirs for emerging viruses? date: 2011-11-09 words: 5616 flesch: 40 summary: Bat viruses may therefore have co-evolved with or adapted to bats over many millions of years. The long life-span of bats may facilitate the transmission of chronic persistent infections, whereas the unusually large and complex structure of bat populations may ensure a sufficient number of immunologically naive juveniles for bat viruses to persist in bat colonies. keywords: bats; disease; diversity; extinction; host; impact; infection; rate; review; species; viruses cache: cord-270803-jtv5jmkn.txt plain text: cord-270803-jtv5jmkn.txt item: #34 of 99 id: cord-271687-sxl8g85p author: Mathews, Fiona title: Chapter 8 Zoonoses in Wildlife: Integrating Ecology into Management date: 2009-03-14 words: 7884 flesch: 41 summary: The spatio-temporal distribution of Mycobacterium bovis (bovine tuberculosis) infection in a high-density badger population Mathematical Epidemiology of Infectious Diseases: Model Building, Analysis and Interpretation What links bats to emerging infectious diseases Positive and negative effects of widespread badger culling on tuberculosis in cattle Impact of localized badger culling on tuberculosis incidence in British cattle Elevated testosterone and reduced 5-HIAA concentrations are associated with wounding and hantavirus infection in male Norway rats A survey of zoonotic pathogens carried by Norway Immunological mechanisms mediating Hantavirus persistence in rodent reservoirs Screening of active lyssavirus infection in wild bat populations by viral RNA or oropharyngeal swabs Microsatellite analysis reveals that female mice are indiscriminate when choosing infected or dominant males in an arena setting A spatial model of shared risk for plague and hantavirus pulmonary syndrome in the southwestern United States Ecologically based control, including the management of conditions leading to spill‐overs into target host populations, is likely to be more effective and sustainable than simple reductions in wildlife populations alone. keywords: animals; bats; btb; cattle; control; culling; disease; et al; host; infection; population; rabies; species; transmission; virus; wildlife cache: cord-271687-sxl8g85p.txt plain text: cord-271687-sxl8g85p.txt item: #35 of 99 id: cord-272009-yxjhfg7m author: Cui, Jie title: Evolutionary Relationships between Bat Coronaviruses and Their Hosts date: 2007-10-17 words: 3547 flesch: 48 summary: We examined the evolutionary relationships between bat CoVs and their hosts by using sequence data of the virus RNA-dependent RNA polymerase gene and the bat cytochrome b gene. We examined the evolutionary relationships between bat CoVs and their hosts by using sequence data of the virus RNA-dependent RNA polymerase gene and the bat cytochrome b gene. keywords: bats; covs; host; sars; shifts; species; viruses cache: cord-272009-yxjhfg7m.txt plain text: cord-272009-yxjhfg7m.txt item: #36 of 99 id: cord-272250-asuxx1ln author: Robertson, Kis title: Rabies-Related Knowledge and Practices Among Persons At Risk of Bat Exposures in Thailand date: 2011-06-28 words: 4906 flesch: 45 summary: In this survey among persons at risk for bat exposure in Thailand, we found that although general awareness of rabies transmission and severity were relatively high, awareness of bat rabies in particular was low, with only 10% of participants identifying bats as a potential source of rabies and 36% failing to say they would take any specific action if bitten or scratched by a bat. These findings indicate the need for educational outreach to raise awareness of bat rabies, promote exposure prevention, and ensure appropriate health-seeking behaviors for bat-inflicted wounds, particularly among at-risk groups in Thailand. keywords: bat; bats; exposures; guano; human; knowledge; lyssavirus; participants; rabies; thailand cache: cord-272250-asuxx1ln.txt plain text: cord-272250-asuxx1ln.txt item: #37 of 99 id: cord-274241-biqbsggu author: Shaw, Timothy I. title: Transcriptome Sequencing and Annotation for the Jamaican Fruit Bat (Artibeus jamaicensis) date: 2012-11-15 words: 6004 flesch: 48 summary: Human and mouse genomes were used as references to estimate the distribution of bat contigs within known gene transcripts. Horse and human were identified as the top two species with best BLAST hits for bat contigs ( Figure 2 ). keywords: analysis; artibeus; bats; contigs; fruit; genes; genome; human; immune; mouse; sequences; species; transcriptome; tree; virus cache: cord-274241-biqbsggu.txt plain text: cord-274241-biqbsggu.txt item: #38 of 99 id: cord-274620-6ebl319q author: Ceballos, Nidia Aréchiga title: Novel Lyssavirus in Bat, Spain date: 2013-05-17 words: 1436 flesch: 44 summary: The cumulative description of new bat lyssaviruses in recent years shows the convenience of always using generic amplification primers for rabies diagnosis based on RT-PCR to complement antigen detection. Bats: important reservoir hosts of emerging viruses Novel lyssavirus in natterer's bat Ikoma lyssavirus, highly divergent novel lyssavirus in African civet Complete genomes of Aravan, Khujand, Irkut and West Caucasian bat viruses, with special attention to the polymerase gene and non-coding regions Current state of bat rabies surveillance in Europe Novel lyssaviruses isolated from bats in Russia Phylogeny of European bat lyssavirus 1 in Eptesicus isabellinus bats in Spain European bat lyssavirus infection in Spanish bat populations Screening of active lyssavirus infection in wild bat populations by viral RNA detection on oropharyngeal swabs RT-PCR for detection of all seven genotypes of Lyssavirus genus The Iberian contribution to cryptic diversity in European bats Molecular phylogenetics of the chiropteran family Vespertilionidae Migratory movements of Miniopterus schreibersii in the north-east of Spain Possible emergence of West Caucasian bat virus in Africa Passive immunity in the prevention of rabies: a neglected tool for a neglected disease We thank the Genomics Unit of the Instituto de Salud Carlos III for the analyses of the genomic sequences. keywords: bat; bats; ikov; lyssavirus; rabies cache: cord-274620-6ebl319q.txt plain text: cord-274620-6ebl319q.txt item: #39 of 99 id: cord-276052-gk6n8slx author: Yadav, Pragya title: Isolation of Tioman virus from Pteropus giganteus bat in North-East region of India date: 2016-09-09 words: 3010 flesch: 44 summary: During the survey for Nipah virus among bats at North-East region of India; Tioman virus (TioV), a new member of the Paramyxoviridae family was isolated from tissues of Pteropus giganteus bats for the first time in India. Emerging paramyxoviruses: molecular mechanisms and antiviral strategies Completion of the full-length genome sequence of Menangle virus: characterization of the polymerase gene and genomic 5-trailer region A negative staining method for high resolution electron microscopy of viruses Bats: important reservoir hosts of emerging viruses Nipah virus-associated encephalitis outbreak Tioman virus, a novel paramyxovirus isolated from fruit bats in Malaysia Isolation of Nipah virus from Malaysian island flying-foxes. keywords: bats; cells; human; india; pteropus; tiov; virus; viruses cache: cord-276052-gk6n8slx.txt plain text: cord-276052-gk6n8slx.txt item: #40 of 99 id: cord-277039-yo5ojr0s author: Mendenhall, Ian H. title: Discovery and Characterization of Novel Bat Coronavirus Lineages from Kazakhstan date: 2019-04-17 words: 2425 flesch: 49 summary: In addition, two distinct lineages of Kazakhstan bat coronaviruses were detected. Both lineages are closely related to bat coronaviruses from China, France, Spain, and South Africa, suggesting that co-circulation of coronaviruses is common in multiple bat species with overlapping geographical distributions. keywords: bat; bats; cave; coronaviruses; cov; kazakhstan; sequences; species cache: cord-277039-yo5ojr0s.txt plain text: cord-277039-yo5ojr0s.txt item: #41 of 99 id: cord-277306-r8jki3x4 author: Osborne, Christina title: Alphacoronaviruses in New World Bats: Prevalence, Persistence, Phylogeny, and Potential for Interaction with Humans date: 2011-05-12 words: 5192 flesch: 52 summary: Similar findings were made in rhinolophid bats in Asia that harbor SARs-like-bat-CoVs [37] and in fruit bats experimentally infected with bat CoVs which showed no signs of illness [39] . To assess the potential for zoonotic transmission of bat CoVs, we focused part of this present work on North American bats that have the closest contact with humans and sampled roosts where big brown bats had histories of contact or potential for contact with people [30] . keywords: bats; brown; colorado; cov; covs; prevalence; rna; sequences; site; species; viruses; world cache: cord-277306-r8jki3x4.txt plain text: cord-277306-r8jki3x4.txt item: #42 of 99 id: cord-277309-kelebqr6 author: Wang, Lin-Fa title: Viruses in bats and potential spillover to animals and humans date: 2019-01-18 words: 6083 flesch: 41 summary: Here we provide a brief review of the latest findings in bat viruses and their potential risk of cross-species transmission. Here we provide a brief review of the latest findings in bat viruses and their potential risk of crossspecies transmission. keywords: bats; coronavirus; cov; disease; humans; novel; outbreak; potential; sars; species; spillover; transmission; viruses; zoonotic cache: cord-277309-kelebqr6.txt plain text: cord-277309-kelebqr6.txt item: #43 of 99 id: cord-281956-obwtd33y author: Mayer, Fabiana Quoos title: Pathogenic Leptospira spp. in bats: Molecular investigation in Southern Brazil date: 2017-05-12 words: 2380 flesch: 44 summary: Association between the frequency of specimens positive for Leptospira spp. and sex, age, bat species or family, season of collection, geographic localization and feeding habits was evaluated. Despite this wide range of bat species and high rates of leptospirosis, there are few Brazilian studies on this subject showing low bat leptospiral infection rates [4, 18] ; however, they were performed in urban areas of Southeast region. keywords: bats; dna; frequency; leptospira; leptospirosis; pathogenic; species; spp cache: cord-281956-obwtd33y.txt plain text: cord-281956-obwtd33y.txt item: #44 of 99 id: cord-283756-ycjzitlk author: Simons, Robin R. L. title: Potential for Introduction of Bat-Borne Zoonotic Viruses into the EU: A Review date: 2014-05-16 words: 14416 flesch: 51 summary: As some viruses such as coronaviruses can survive for long periods in water [157] , bat guano or even dead bats transported in bilge waters of ships could, in theory, serve as route of transport of bat viruses around the world. It should also be noted that migration could pose a risk for other bat viruses which may be present on these migration routes. keywords: aegyptiacus; africa; areas; bangladesh; bats; bushmeat; cases; countries; evidence; fruit; human; infection; introduction; marv; nipah; niv; potential; risk; species; study; trade; transmission; virus; viruses cache: cord-283756-ycjzitlk.txt plain text: cord-283756-ycjzitlk.txt item: #45 of 99 id: cord-284015-vvtv492b author: Nikaido, Masato title: Comparative genomic analyses illuminate the distinct evolution of megabats within Chiroptera date: 2020-09-23 words: 8601 flesch: 43 summary: RepbaseSubmitter and censor Simple and fast classification of non-LTR retrotransposons based on phylogeny of their RT domain protein sequences Repbase update, a database of repetitive elements in eukaryotic genomes PAML 4: a program package for phylogenetic analysis by maximum likelihood The PyMOL molecular graphics system A genomic approach to examine the complex evolution of laurasiatherian mammals A molecular phylogeny for bats illuminates biogeography and the fossil record Characterization of the mitochondrial genome of Rousettus leschenaulti Dynamics of genome size evolution in birds and mammals Transposable elements as genetic accelerators of evolution: contribution to genome size, gene regulatory network rewiring, and morphological innovation Pinpointing the vesper bat transposon revolution using the Miniopterus natalensis genome 5S rRNA-derived and tRNA-derived SINEs in fruit bats Origin of avian genome size and structure in non-avian dinosaurs Palaeogenomics of pterosaurs and the evolution of small genome size in flying vertebrates Loss of LINE-1 activity in the megabats Reviving the dead: history and reactivation of an extinct L1 Viral encounters with 2 0 ,5 0 -oligoadenylate synthetase and RNase L during the interferon antiviral response RNase L restricts the mobility of engineered retrotransposons in cultured human cells Restricting retrotransposons: a review LINE-mediated retrotransposition of marked Alu sequences The evolution of animal chemosensory receptor gene repertoires: roles of chance and necessity Dramatic variation of the vomeronasal pheromone receptor gene repertoire among five orders of placental and marsupial mammals A cluster of olfactory receptor genes linked to frugivory in bats Genomic and genetic evidence for the loss of umami taste in bats Extreme variability among mammalian V1R gene families Prenatal development supports a single origin of laryngeal echolocation in bats Evolution of the sweet taste receptor gene Tas1r2 in bats Frequent expansions of the bitter taste receptor gene repertoire during evolution of mammals in the Euarchontoglires clade Formyl peptide receptor-like proteins are a novel family of vomeronasal chemosensors Adaptive evolution of formyl peptide receptors in mammals Molecular organization of vomeronasal chemoreception From genes to social communication: molecular sensing by the vomeronasal organ Evolution of V1R pheromone receptor genes in vertebrates: diversity and commonality Widespread losses of vomeronasal signal transduction in bats Trpc2 pseudogenization dynamics in bats reveal ancestral vomeronasal signaling, then pervasive loss A single pheromone receptor gene conserved across 400 million years of vertebrate evolution Inactivation of ancV1R as a predictive signature for the loss of vomeronasal system in mammals Vomeronasal organ in bats and primates: extremes of structural variability and its phylogenetic implications Expressed vomeronasal type-1 receptors (V1rs) in bats uncover conserved sequences underlying social chemical signaling A novel family of putative pheromone receptors in mammals with a topographically organized and sexually dimorphic distribution A multigene family encoding a diverse array of putative pheromone receptors in mammals The male mouse pheromone ESP1 enhances female sexual receptive behaviour through a specific vomeronasal receptor Sexual rejection via a vomeronasal receptor-triggered limbic circuit First evidence for functional vomeronasal 2 receptor genes in primates Comparative genomic analysis identifies an evolutionary shift of vomeronasal receptor gene repertoires in the vertebrate transition from water to land A renaissance in trace amines inspired by a novel gpcr family A second class of chemosensory receptors in the olfactory epithelium Trace amine-associated receptors: ligands, neural circuits, and behaviors Molecular evolution and functional divergence of trace amine-associated receptors MHC-dependent mate choice is linked to a trace-amine-associated receptor gene in a mammal WebGestalt, a more comprehensive, powerful, flexible and interactive gene set enrichment analysis toolkit Pangolin genomes and the evolution of mammalian scales and immunity Isolation of SARS-CoV-2-related coronavirus from Malayan pangolins Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins Adaptive evolution in the glucose transporter 4 gene Slc2a4 in Old World fruit bats (family: pteropodidae) It is possible that megabats re-allocated the diversity in chemosensory receptor genes as a sensory trade-off, given that megabats have experienced the secondary loss of echolocation ability, which is one of the most specialized senses in bats. keywords: analyses; evolution; fig; fruit; fruit bat; genes; genome; mammals; megabats; microbats; receptor; rousette; sequences; species; supplementary; taars; table; tes cache: cord-284015-vvtv492b.txt plain text: cord-284015-vvtv492b.txt item: #46 of 99 id: cord-284367-cy61pjcb author: MULEYA, Walter title: Molecular Epidemiology of Paramyxoviruses in Frugivorous Eidolon helvum Bats in Zambia date: 2013-12-31 words: 1566 flesch: 44 summary: The viruses identified in this study were shown to originate from wide geographical areas, and their presence in fruit bat species might pose a public health risk and as such, continued surveillance of these viruses in fruit bats in essential. key: cord-284367-cy61pjcb authors: MULEYA, Walter; SASAKI, Michihito; ORBA, Yasuko; ISHII, Akihiro; THOMAS, Yuka; NAKAGAWA, Emiko; OGAWA, Hirohito; HANG’OMBE, Bernard; NAMANGALA, Boniface; MWEENE, Aaron; TAKADA, Ayato; KIMURA, Takashi; SAWA, Hirofumi title: Molecular Epidemiology of Paramyxoviruses in Frugivorous Eidolon helvum Bats in Zambia date: 2013-12-31 journal: J Vet Med Sci DOI: 10.1292/jvms.13-0518 sha: doc_id: 284367 cord_uid: cy61pjcb In this study, we describe the detection of novel paramyxoviruses from the Eidolon helvum species of fruit bats. keywords: bats; fruit; novel; paramyxoviruses; pcr; samples cache: cord-284367-cy61pjcb.txt plain text: cord-284367-cy61pjcb.txt item: #47 of 99 id: cord-286708-igu984oc author: Chua, Kaw Bing title: Identification and Characterization of a New Orthoreovirus from Patients with Acute Respiratory Infections date: 2008-11-25 words: 4366 flesch: 47 summary: The discovery of Kampar virus highlights the increasing trend of emergence of bat zoonotic viruses and the need to expand our understanding of bats as a source of many unknown viruses. In conclusion, the discovery and characterization of KamV corroborate our previous work on MelV and demonstrate the increasing risk posed by unknown bat viruses which are capable of infecting and causing disease in humans. keywords: bats; case; fruit; human; kampar; kamv; melv; nbv; species; virus; viruses cache: cord-286708-igu984oc.txt plain text: cord-286708-igu984oc.txt item: #48 of 99 id: cord-287131-svtdfeop author: Campos, Angélica Cristine Almeida title: Bat Influenza A(HL18NL11) Virus in Fruit Bats, Brazil date: 2019-02-17 words: 1580 flesch: 37 summary: Apparently low rates of acute influenza A virus infection in bats are not consistent with high seroprevalence of 72% in different bat species according to a preliminary investigation (5) and may hint at seasonal variation in bat influenza virus infections, comparable to other batborne RNA viruses (9) . This result suggests preservation of the biologic activity of these glycoproteins in different bat species and supported a broadly conserved cellular receptor of bat influenza A viruses that differs from sialic acid receptors used by avian-associated influenza A viruses (10) . keywords: bat; bats; brazil; hl18nl11; influenza; viruses cache: cord-287131-svtdfeop.txt plain text: cord-287131-svtdfeop.txt item: #49 of 99 id: cord-287748-co9j3uig author: Kobayashi, Tomoya title: Detection of bat hepatitis E virus RNA in microbats in Japan date: 2018-05-29 words: 1390 flesch: 52 summary: Although there is no information about migration of E. japonensis and P. sacrimontis, bat species closely related to them were reported to migrate only a few kilometers from their colonies per night key: cord-287748-co9j3uig authors: Kobayashi, Tomoya; Murakami, Shin; Yamamoto, Terumasa; Mineshita, Ko; Sakuyama, Muneki; Sasaki, Reiko; Maeda, Ken; Horimoto, Taisuke title: Detection of bat hepatitis E virus RNA in microbats in Japan date: 2018-05-29 journal: Virus Genes DOI: 10.1007/s11262-018-1577-9 sha: doc_id: 287748 cord_uid: co9j3uig Several recent studies have reported that various bat species harbor bat hepatitis E viruses (BatHEV) belonging to the family Hepeviridae, which also contains human hepatitis E virus (HEV). keywords: bat; bats; bthev; species cache: cord-287748-co9j3uig.txt plain text: cord-287748-co9j3uig.txt item: #50 of 99 id: cord-288451-npefpo3t author: Yinda, Claude Kwe title: Novel highly divergent reassortant bat rotaviruses in Cameroon, without evidence of zoonosis date: 2016-09-26 words: 4459 flesch: 47 summary: Therefore, zoonotic events of bat RVA strains could easily be missed with the current screening primers depending on the primer combinations, PCR conditions and/or circulating zoonotic strains. Even though there exists a considerable genetic divergence between bat RVA and human RVA, suggestions have been made about potential interspecies transmission of Chinese and Kenyan bat RVA strains. keywords: bat; bats; genotype; human; primers; rotavirus; rva; rvas; samples; segments; strains; vp7 cache: cord-288451-npefpo3t.txt plain text: cord-288451-npefpo3t.txt item: #51 of 99 id: cord-289555-1z4vbldd author: Mühldorfer, Kristin title: Diseases and Causes of Death in European Bats: Dynamics in Disease Susceptibility and Infection Rates date: 2011-12-28 words: 5766 flesch: 38 summary: For hypotheses A and B, we used a generalized linear mixed modeling approach (binomial GLMM using function lmer in library lme4) with bat species included as random effect. Additional findings of our parasite analyses are distinct variations in ecto-and endoparasite prevalence in relation to bat species. keywords: age; bacterial; bats; differences; disease; european; germany; infection; mortality; prevalence; species; table cache: cord-289555-1z4vbldd.txt plain text: cord-289555-1z4vbldd.txt item: #52 of 99 id: cord-289584-rbp7p8s9 author: Zhou, Ling title: Retrospective detection and phylogenetic analysis of swine acute diarrhoea syndrome coronavirus in pigs in southern China date: 2019-01-09 words: 2242 flesch: 46 summary: Molecular Evolutionary Genetics analysis version 7.0 for bigger datasets Evolution, antigenicity and pathogenicity of global porcine epidemic diarrhea virus strains The porcine microRNA transcriptome response to transmissible gastroenteritis virus infection The detection and phylogenetic analysis of porcine deltacoronavirus from Guangdong Province in Southern China Discovery of a novel swine enteric alphacoronavirus (SeA-CoV) in southern China Emergence of Porcine epidemic diarrhea virus in the United States: Clinical signs, lesions, and viral genomic sequences Outbreak of porcine epidemic diarrhea in suckling piglets Epidemiology and vaccine of porcine epidemic diarrhea virus in China: A mini-review Prospects for inferring very large phylogenies by using the neighbor-joining method Genetic analysis of porcine respiratory coronavirus, an attenuated variant of transmissible gastroenteritis virus Coronavirus genomics and bioinformatics analysis Discovery of seven novel Mammalian and Avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus The rate of co-infection for piglet diarrhea viruses in China and the genetic characterization of porcine epidemic diarrhea virus and porcine kobuvirus Fatal Swine Acute Diarrhea Syndrome caused by an HKU2-related Coronavirus of Bat Origin Multiple sequence alignmentwith the Clustal series of programs Porcine Deltacoronavirus in Mainland China Measurably evolving populations Epidemiological survey of porcine epidemic diarrhea virus in swine farms in A new bat-HKU2-like coronavirus in swine Phylogenetic and epidemic modeling of rapidly evolving infectious diseases MEGA7: keywords: bat; coronavirus; cov; sads cache: cord-289584-rbp7p8s9.txt plain text: cord-289584-rbp7p8s9.txt item: #53 of 99 id: cord-291965-9r9ll83m author: Pfefferle, Susanne title: Distant Relatives of Severe Acute Respiratory Syndrome Coronavirus and Close Relatives of Human Coronavirus 229E in Bats, Ghana date: 2009-09-17 words: 4314 flesch: 50 summary: Because of the low concentration of RNA in bat samples, generation of long sequences from novel bat CoV is tedious and technically demanding, which may be why some published phylogenies of bat CoV are based on short datasets, making it difficult to use these data for reference. However, the absence of successful virus isolation from bat feces in previous studies (3) (4) (5) (6) 8, 11, 12) may not reflect the incapability of bat CoV to infect human cells. keywords: analysis; bats; coronavirus; cov; covs; group; human; samples; sars; study; virus cache: cord-291965-9r9ll83m.txt plain text: cord-291965-9r9ll83m.txt item: #54 of 99 id: cord-293946-4bquxdqa author: Huong, Nguyen Quynh title: Coronavirus testing indicates transmission risk increases along wildlife supply chains for human consumption in Viet Nam, 2013-2014 date: 2020-08-10 words: 6230 flesch: 46 summary: [31] to explore phylogenetic relationships among bat coronavirus 512/2005 sequences at the intraspecies level, as haplotype networks may better represent the relationships among viral sequences with low sequence diversity compared with phylogenetic trees We observed two main clusters and a shallow geographic structure of genetic diversity, perhaps illustrative of sampling effort but also of localized transmission and circulation of bat coronavirus 512/2005 strains in these provinces. keywords: animals; bat; bats; coronavirus; farms; field; guano; human; nam; rats; rodents; samples; sites; species; trade; viet; wildlife cache: cord-293946-4bquxdqa.txt plain text: cord-293946-4bquxdqa.txt item: #55 of 99 id: cord-294698-mtfrbn87 author: Kim, H. K. title: Detection of Severe Acute Respiratory Syndrome‐Like, Middle East Respiratory Syndrome‐Like Bat Coronaviruses and Group H Rotavirus in Faeces of Korean Bats date: 2016-05-23 words: 2689 flesch: 51 summary: Therefore, in this study, we investigated viruses in bat species in Korea, using 49 faecal samples collected from July to December 2015 in 11 sites in natural bat habitats. This may imply that other strains or types of those coronaviruses may circulate in bat species in Korea. keywords: b15; bat; bats; cov; sars; viruses cache: cord-294698-mtfrbn87.txt plain text: cord-294698-mtfrbn87.txt item: #56 of 99 id: cord-295433-olmein3q author: Banerjee, Arinjay title: Bats and Coronaviruses date: 2019-01-09 words: 5661 flesch: 47 summary: Unlike the amount of information available from studies of other bat viruses such as Nipah, Hendra, Ebola, and Marburg viruses, we know very little, if anything about how coronaviruses are transmitted directly to humans or if direct human transmission does not occur and spillover via an intermediate host is required. Bats are known to harbor a wide range of viruses including many that are highly pathogenic in humans. This pulse of virus positive bats correlates with an increased incidence of human spillover events [68] . keywords: bats; cells; coronavirus; cov; human; mers; sars; species; studies; study; syndrome; virus; viruses cache: cord-295433-olmein3q.txt plain text: cord-295433-olmein3q.txt item: #57 of 99 id: cord-295554-0pzjyrdf author: Lima, Francisco Esmaile de Sales title: Detection of Alphacoronavirus in velvety free-tailed bats (Molossus molossus) and Brazilian free-tailed bats (Tadarida brasiliensis) from urban area of Southern Brazil date: 2013-03-16 words: 1788 flesch: 52 summary: In this initial study, samples were restricted in location and variety of bat species, and we found only alphacoronaviruses. Additional studies with larger numbers of bats and bat species, as well as the continued vigilance on the occurrence of viral infections in bats over the years is required to follow the evolution of bat coronaviruses in its interactions with the different bat host species. keywords: bats; brazil; coronavirus; rna; species; viruses cache: cord-295554-0pzjyrdf.txt plain text: cord-295554-0pzjyrdf.txt item: #58 of 99 id: cord-295727-s63lffi8 author: Lima, Luciana title: Trypanosoma livingstonei: a new species from African bats supports the bat seeding hypothesis for the Trypanosoma cruzi clade date: 2013-08-03 words: 7194 flesch: 40 summary: Sequences from the new bat isolates were compared to those from other bat trypanosomes determined in this and in previous studies (including other isolates morphologically assignable to the subgenus Megatrypanum) to address taxonomic questions about bat trypanosomes. Oral infection through the predation of infected bats by other mammals and by the consumption of insect vectors by bats probably played important roles in the colonisation of new hosts by bat trypanosomes. keywords: bat; bats; blood; clade; cruzi; figure; isolates; livingstonei; megatrypanum; sequences; species; subgenus; t. cruzi; trypanosomes cache: cord-295727-s63lffi8.txt plain text: cord-295727-s63lffi8.txt item: #59 of 99 id: cord-297790-tpjxt0w5 author: Mandl, Judith N. title: Going to Bat(s) for Studies of Disease Tolerance date: 2018-09-20 words: 9488 flesch: 28 summary: Given the diversity of the Chiroptera order (Figure 1) , we may simply see more bat viruses because there are so many (>1,300) species of bats (31) . Fewer studies have examined the adaptive immune system than those probing innate immune pathways, but experimental infections with bat borne viruses have demonstrated that bats generate low or absent antibody responses which often wane rapidly. keywords: aegyptiacus; alecto; bats; cell; dna; evidence; genes; host; humans; ifn; infection; reservoir; responses; rna; species; studies; virus; viruses cache: cord-297790-tpjxt0w5.txt plain text: cord-297790-tpjxt0w5.txt item: #60 of 99 id: cord-303941-3lg1bzsi author: Han, Hui-Ju title: Bats as reservoirs of severe emerging infectious diseases date: 2015-07-02 words: 4680 flesch: 46 summary: Metagenomic analysis of the viromes of three North American bat species: viral diversity among different bat species that share a common habitat Transmission of Ebola hemorrhagic fever: a study of risk factors in family members Bats host major mammalian paramyxoviruses Amplification of emerging viruses in a bat colony Ecology of Bat Migration Metagenomic analysis of viruses from bat fecal samples reveals many novel viruses in insectivorous bats in China Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor Host and viral ecology determine bat rabies seasonality and maintenance Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China Isolation of Hendra virus from pteropid bats: a natural reservoir of Hendra virus Virome profiling of bats from Myanmar by metagenomic analysis of tissue samples reveals more novel Mammalian viruses Close relative of human Middle East respiratory syndrome coronavirus in bat Early eocene bat from wyoming Isolation and partial characterisation of a new virus causing acute haemorrhagic fever in Zaire Bats, clocks, and rocks: diversification patterns in Chiroptera Ebola virus disease in health care workers -sierra leone Nipah virus encephalitis outbreak in Malaysia Severe acute respiratory syndrome coronaviruslike virus in Chinese horseshoe bats Human Ebola outbreak resulting from direct exposure to fruit bats in Luebo, Democratic Republic of Congo Fruit bats as reservoirs of Ebola virus Bats are natural reservoirs of SARS-like coronaviruses SARS, wildlife, and human health Recurrent zoonotic transmission of Nipah virus into humans Human infection with MERS coronavirus after exposure to infected camels Middle East respiratory syndrome coronavirus in bats, Saudi Arabia Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines A morbillivirus that caused fatal disease in horses and humans Outbreak of Nipah-virus infection among abattoir workers in Singapore Rabies in the vampire bat of Trinidad, with special reference to the clinical course and the latency of infection The transmission of paralytic rabies in Trinidad by the vampire bat (Desmodus rotundus murinus Wagner Ecological dynamics of emerging bat virus spillover Bats are a major natural reservoir for hepaciviruses and pegiviruses Characterization of Nipah virus from naturally infected Pteropus vampyrus bats Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC Difference in receptor usage between severe acute respiratory syndrome (SARS) coronavirus and SARS-like coronavirus of bat origin Ebola haemorrhagic fever in Zaire Middle East respiratory syndrome coronavirus (MERS-CoV) RNA and neutralising antibodies in milk collected according to local customs from dromedary camels Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study Mammal Species of the World: A Taxonomic and Geographic Reference, 3 vols Virus infections in bats Marburg Hemorrhagic Fever-The Netherlands ex Uganda Correlates of viral richness in bats (order Chiroptera) Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans Now arriving, the deadly Ebola virus lands in America Bat origins of MERS-CoV supported by bat coronavirus HKU4 usage of human receptor CD26 Negative findings from serological studies of equine morbillivirus in the Queensland horse population Novel Henipa-like virus, Mojiang Paramyxovirus, in rats MERS-related betacoronavirus in Vespertilio superans bats Nipah virus infection in bats (order Chiroptera) in peninsular Malaysia Serologic evidence for the presence in Pteropus bats of a paramyxovirus related to equine morbillivirus Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia The huge diversity of bat species can provide a large breeding ground for viruses. keywords: bats; cov; ebola; et al; humans; mers; sars; transmission; viruses cache: cord-303941-3lg1bzsi.txt plain text: cord-303941-3lg1bzsi.txt item: #61 of 99 id: cord-304481-yqc8r3ll author: Luis, Angela D. title: Network analysis of host–virus communities in bats and rodents reveals determinants of cross‐species transmission date: 2015-08-24 words: 5997 flesch: 46 summary: Assortativity in bats was significant, suggesting that bat species with high degree tend to interact with other bat species of high degree (and low degree with low degree), but there is no evidence of this in rodents (Table 1) . bat species with distributions that overlap with a greater number of other bat species, and particularly those which are gregarious, will have greater interspecific contacts and chance for cross-species transmission. keywords: bats; degree; et al; host; network; number; rodents; species; transmission; viruses cache: cord-304481-yqc8r3ll.txt plain text: cord-304481-yqc8r3ll.txt item: #62 of 99 id: cord-304850-9xetsc2c author: Drosten, Christian title: Virus ecology: a gap between detection and prediction date: 2013-05-22 words: 1501 flesch: 41 summary: Emerging Microbes and Infections A distinct lineage of influenza A virus from bats The neuraminidase of bat influenza viruses is not a neuraminidase Host species barriers to influenza virus infections Bats host major mammalian paramyxoviruses Novel potentially-zoonotic paramyxoviruses from the African straw-colored fruit bat, Eidolon helvum Measles eradication: past is prologue Characterization of a canine homolog of hepatitis C virus Serology-enabled discovery of genetically diverse hepaciviruses in a new host Infectious diseases in primitive societies Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia Human betacoronavirus 2c EMC/2012-related viruses in bats, Ghana and Europe What links bats to emerging infectious diseases? Crossing the line: selection and evolution of virulence traits Seasonal pulses of Marburg virus circulation in juvenile Rousettus aegyptiacus bats coincide with periods of increased risk of human infection Amplification of emerging viruses in a bat colony Canine hepacivirus NS3 serine protease can cleave the human adaptor proteins MAVS and TRIF Viral immune modulators perturb the human molecular network by common and unique strategies The Deutsche Forschungsgemeinschaft (Germany's national research council) has established a priority program on ecology and species barriers in emerging viral diseases (coordinator's grant to Christian Drosten, DR 772/10-1). key: cord-304850-9xetsc2c authors: Drosten, Christian title: Virus ecology: a gap between detection and prediction date: 2013-05-22 journal: Emerg Microbes Infect DOI: 10.1038/emi.2013.25 sha: doc_id: 304850 cord_uid: 9xetsc2c nan Virologists have been surprised by a recent report that has changed our long-standing conception of the ecology of influenza viruses. keywords: bat; bats; host; human; viruses cache: cord-304850-9xetsc2c.txt plain text: cord-304850-9xetsc2c.txt item: #63 of 99 id: cord-305024-343l2ha7 author: Sonntag, Michael title: New Adenovirus in Bats, Germany date: 2009-12-17 words: 1690 flesch: 33 summary: The obtained sequence of a fragment of the DNA polymerase gene (≈550 bp) indicated that the viruses were a novel virus type within the genus Mastadenovirus and was tentatively named bat adenovirus 2 (bat AdV-2) strain P. pipistrellus virus 1 (PPV1). To obtain additional sequence information of bat AdV-2, a random PCR method (virus discovery based on cDNA-amplifi ed fragment length polymorphism) (11) was applied, which showed >20 adenovirus sequences distributed over the genome (Figure 1, panel B) . keywords: adenovirus; bats; dna; pcr; sequence; species; virus cache: cord-305024-343l2ha7.txt plain text: cord-305024-343l2ha7.txt item: #64 of 99 id: cord-305857-2409me0p author: López-Roig, Marc title: Seroprevalence Dynamics of European Bat Lyssavirus Type 1 in a Multispecies Bat Colony date: 2014-09-04 words: 3882 flesch: 45 summary: key: cord-305857-2409me0p authors: López-Roig, Marc; Bourhy, Hervé; Lavenir, Rachel; Serra-Cobo, Jordi title: Seroprevalence Dynamics of European Bat Lyssavirus Type 1 in a Multispecies Bat Colony date: 2014-09-04 journal: Viruses DOI: 10.3390/v6093386 sha: doc_id: 305857 cord_uid: 2409me0p We report an active surveillance study of the occurrence of specific antibodies to European Bat Lyssavirus Type 1 (EBLV-1) in bat species, scarcely studied hitherto, that share the same refuge. Currently, there are about 1200 recognized bat species worldwide, accounting for approximately 21% of all mammalian species. keywords: austriacus; bat; bats; colonies; eblv-1; seroprevalence; species; teniotis cache: cord-305857-2409me0p.txt plain text: cord-305857-2409me0p.txt item: #65 of 99 id: cord-308614-gsgntf4c author: Eshar, David title: Venipuncture in bats date: 2010 words: 1329 flesch: 55 summary: in Zoo Animal And Wildlife Immobilization And Anesthesia A method of bleeding small bats A new method of bleeding small and infant bats Public health awareness of emerging zoonotic viruses of bats: a European perspective Basal, diurnal, and stress-induced levels of glucose and glucocorticoids in captive bats Comparison of serum and plasma for determination of blood biochemical values in Malaysian flying foxes (Pteropus vampyrus) A 25-gauge needle can be used to puncture the vessel in small bats, and the tube can be inserted into the hub of the needle to collect the sample, or if a vein is accidently punctured, blood can be collected into a microhematocrit capillary tube directly from the incision site 2 (Fig. 1) . keywords: bats; blood; sample; vein cache: cord-308614-gsgntf4c.txt plain text: cord-308614-gsgntf4c.txt item: #66 of 99 id: cord-308932-pp8etmwq author: Baker, M. L. title: Antiviral Immune Responses of Bats: A Review date: 2012-08-01 words: 8602 flesch: 34 summary: Pteropid bat cells and cell lines readily secrete IFN in response to stimulation with synthetic TLR ligands including polyinosine-polycytidylic acid (polyIC) and lipopolysaccharide (LPS), demonstrating that IFN production pathways are functional in bat cells (Stewart et al., 1969a; Crameri et al., 2009; Kepler et al., 2010; Zhou et al., 2011b) . Recently, evidence for differences in the IFN responses of bats and the ability of viruses to evade the IFN response of bat cells have also been described. keywords: antibody; bats; cells; et al; evidence; genes; ifn; immunity; infection; mammals; pteropus; responses; species; studies; type; virus; viruses cache: cord-308932-pp8etmwq.txt plain text: cord-308932-pp8etmwq.txt item: #67 of 99 id: cord-309512-d8n9711b author: Bacus, Michael G. title: Global genetic patterns reveal host tropism versus cross-taxon transmission of bat Betacoronaviruses date: 2020-05-05 words: 1026 flesch: 35 summary: For example, bat hosts that belong to genetically 212 unrelated taxa were mixed in some BetaCoV groups. In the succeeding discussions, we will present two deviant phenomena that 286 exemplify this: cross-taxon transmission of CoVs and bat hosts with multi-CoV lineages. keywords: bat; bats; betacovs; host cache: cord-309512-d8n9711b.txt plain text: cord-309512-d8n9711b.txt item: #68 of 99 id: cord-310061-nro623aa author: Valitutto, Marc T. title: Detection of novel coronaviruses in bats in Myanmar date: 2020-04-09 words: 3682 flesch: 42 summary: Supporting information S1 Fauci AS The challenge of emerging and reemerging infectious diseases Factors in the emergence of infectious diseases Host range and emerging and reemerging pathogens Global trends in emerging infectious diseases Risk factors for human disease emergence Human ecology in pathogenic landscapes: two hypotheses on how land use change drives viral emergence Ecology of zoonoses; natural and unnatural histories Impacts of biodiversity on the emergence and transmission of infectious diseases Diseases of humans and their domestic mammals: pathogen characteristics, host range and the risk of emergence Bat origin of human coronaviruses Bats: Important reservoir hosts of emerging viruses Host and viral traits predict zoonotic spillover from mammals Bats as reservoirs of severe emerging infectious diseases Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor Bats are natural reservoirs of SARS-like coronaviruses Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats Middle East respiratory syndrome coronavirus in bats, Saudi Arabia Further evidence for bats as the evolutionary source of Middle East respiratory syndrome coronavirus A pneumonia outbreak associated with a new coronavirus of probable bat origin Global epidemiology of bat coronaviruses Bats and coronaviruses Discovery of seven novel mammalian and avian coronaviruses in the genus Deltacoronavirus supports bat coronaviruses as the gene source of Alphacoronavirus and Betacoronavirus and avian coronaviruses as the gene source of Gammacoronavirus and Deltacoronavirus Fatal swine acute diarrhea syndrome caused by an HKU2-related coronavirus of bat origin A new bat-HKU2-like coronavirus in swine Prevalence and genetic diversity of coronaviruses in bats from China Bat coronavirus in Brazil related to Appalachian Ridge and porcine epidemic diarrhea viruses Ecosystem services provided by bats Global patterns in coronavirus diversity Optimizing viral discovery in bats Global hotspots and correlates of emerging zoonotic diseases Emerging infectious diseases in southeast Asia: regional challenges to control Zoonoses in South-East Asia: a regional burden, a global threat Bat coronaviruses and experimental infection of bats, the Philippines Identification of a severe acute respiratory syndrome coronavirus-like virus in a leaf-nosed bat in Nigeria Identification of mosquito bloodmeals using mitochondrial cytochrome oxidase subunit I and cytochrome b gene sequences PREDICT 1 & 2 Test Data HealthMap Database Group C betacoronavirus in bat guano fertilizer Coronaviruses in guano from Pteropus medius bats in Peradeniya Diversity of coronavirus in bats from Eastern Thailand Virome profiling of bats from Myanmar by metagenomic analysis of tissue samples reveals more novel mammalian viruses Circulation of Alphacoronavirus, Betacoronavirus and Paramyxovirus in Hipposideros bat species in Zimbabwe Recombination, reservoirs, and the modular spike: mechanisms of coronavirus cross-species transmission Bats, coronaviruses, and deforestation: Toward the emergence of novel infectious diseases? key: cord-310061-nro623aa authors: Valitutto, Marc T.; Aung, Ohnmar; Tun, Kyaw Yan Naing; Vodzak, Megan E.; Zimmerman, Dawn; Yu, Jennifer H.; Win, Ye Tun; Maw, Min Thein; Thein, Wai Zin; Win, Htay Htay; Dhanota, Jasjeet; Ontiveros, Victoria; Smith, Brett; Tremeau-Brevard, Alexandre; Goldstein, Tracey; Johnson, Christine K.; Murray, Suzan; Mazet, Jonna title: Detection of novel coronaviruses in bats in Myanmar date: 2020-04-09 journal: PLoS One DOI: 10.1371/journal.pone.0230802 sha: doc_id: 310061 cord_uid: nro623aa The recent emergence of bat-borne zoonotic viruses warrants vigilant surveillance in their natural hosts. keywords: bats; coronaviruses; guano; health; host; human; myanmar; samples; sars; species cache: cord-310061-nro623aa.txt plain text: cord-310061-nro623aa.txt item: #69 of 99 id: cord-310734-6v7oru2l author: Bolatti, Elisa M. title: A Preliminary Study of the Virome of the South American Free-Tailed Bats (Tadarida brasiliensis) and Identification of Two Novel Mammalian Viruses date: 2020-04-09 words: 8482 flesch: 37 summary: Ubiquitous Viruses With Small Genomes and a Diverse Host Range Determination of the origin cleavage and joining domain of geminivirus Rep proteins Identification of the nicking tyrosine of geminivirus Rep protein A single rep protein initiates replication of multiple genome components of faba bean necrotic yellows virus, a single-stranded DNA virus of plants Geminivirus replication proteins are related to prokaryotic plasmid rolling circle DNA replication initiator proteins Conserved sequence and structural motifs contribute to the DNA binding and cleavage activities of a geminivirus replication protein Functional analysis of a novel motif conserved across geminivirus Rep proteins A new superfamily of putative NTP-binding domains encoded by genomes of small DNA and RNA viruses A common set of conserved motifs in a vast variety of putative nucleic acid-dependent ATPases including MCM proteins involved in the initiation of eukaryotic DNA replication The oligomeric Rep protein of Mungbean yellow mosaic India virus (MYMIV) is a likely replicative helicase DNA Helicase Activity Is Associated with the Replication Initiator Protein Rep of Tomato Yellow Leaf Curl Geminivirus Contaminating viral sequences in high-throughput sequencing viromics: A linkage study of 700 sequencing libraries Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection Development and Optimization of Metagenomic Next-Generation Sequencing Methods for Cerebrospinal Fluid Diagnostics Quality control implementation for universal characterization of DNA and RNA viruses in clinical respiratory samples using single metagenomic next-generation sequencing workflow Metagenomic Analysis of Viruses from Bat Fecal Samples Reveals Many Novel Viruses in Insectivorous Bats in China Evaluation of rapid and simple techniques for the enrichment of viruses prior to metagenomic virus discovery Limited reverse transcriptase activity of phi29 DNA polymerase Deciphering the bat virome catalog to better understand the ecological diversity of bat viruses and the bat origin of emerging infectious diseases High diversity of rabies viruses associated with insectivorous bats in Argentina: The analysis also identified (although in low counts) viral sequences related to the family Alloherpesviridae, which infects fish and amphibians. keywords: analysis; bat; bats; brasiliensis; contigs; dna; families; gene; genome; metagenomic; novel; pairs; protein; read; rep; samples; sequence; species; tbrapv1; viruses cache: cord-310734-6v7oru2l.txt plain text: cord-310734-6v7oru2l.txt item: #70 of 99 id: cord-313472-skcaw9ls author: Suwannarong, Kanokwan title: Risk factors for bat contact and consumption behaviors in Thailand; a quantitative study date: 2020-06-03 words: 4414 flesch: 47 summary: This study provides a better understanding of the sociodemographic factors, knowledge, attitudes, perceptions and practices that might influence bat contact and bat consumption behaviors. The objective of this study was to determine the factors associated with bat contact and bat consumption behaviors in ten provinces of Thailand from May 2016 to December 2017. keywords: bat; bats; consumption; contact; factors; provinces; respondents; study cache: cord-313472-skcaw9ls.txt plain text: cord-313472-skcaw9ls.txt item: #71 of 99 id: cord-315972-5g2hnk1x author: Tong, Suxiang title: Detection of Novel SARS-like and Other Coronaviruses in Bats from Kenya date: 2009-03-17 words: 1701 flesch: 50 summary: For the pan-bat coronavirus RT-PCR, conserved primers were designed from the same highly conserved regions based on available bat CoV sequences and presumed to be more specifi c to bat coronaviruses (1st and 2nd round forward 5′-ATGGGITGGGAYTATCCWAARTGTG-3′; 1st round reverse 5′-TATTATARCAIACIACRCCATCRTC-3′; 2nd round reverse 5′-CTGGTICCACCI GGYTTNACRTA-3′). The pattern of CoV detections by bat species and location demonstrates several features concerning coronaviruses in bats. keywords: bats; coronaviruses; cov; covs; like; sars cache: cord-315972-5g2hnk1x.txt plain text: cord-315972-5g2hnk1x.txt item: #72 of 99 id: cord-316343-u1uup5da author: Luo, Yun title: Longitudinal Surveillance of Betacoronaviruses in Fruit Bats in Yunnan Province, China During 2009–2016 date: 2018-02-01 words: 3511 flesch: 52 summary: immunopathology Middle east respiratory syndrome coronavirus (MERS-CoV): announcement of the coronavirus study group Identification of a novel coronavirus in patients with severe acute respiratory syndrome Xi River virus, a new bat reovirus isolated in southern China Metagenomic analysis of viruses from bat fecal samples reveals many novel viruses in insectivorous bats in China Filovirus RNA in fruit bats Bat origin of human coronaviruses A bat-derived putative cross-family recombinant coronavirus with a reovirus gene The nature of flight-the molecules and mechanics of flight in animals Seroprevalence of rabies virus antibodies in bats from southern China Coexistence of different genotypes in the same bat and serological characterization of Rousettus bat coronavirus HKU9 belonging to a novel Betacoronavirus subgroup Bats are natural reservoirs of SARS-like coronaviruses Antibodies to Nipah or Nipah-like viruses in bats Characterization and pathogenicity of a novel mammalian orthoreovirus from wild short-nosed fruit bats Generic detection of coronaviruses and differentiation at the prototype strain level by reverse transcription-PCR and nonfluorescent low-density microarray Bats as bushmeat: a global review Emerging infectious diseases associated with bat viruses Bartonella, bats and bugs: a review Novel bat adenoviruses with low G?C content shed new light on the evolution of adenoviruses Comparative analysis of twelve genomes of three novel group 2c and group 2d coronaviruses reveals unique group and subgroup features Genetically diverse filoviruses in Rousettus and Eonycteris spp. These fruit bats feed on fruits and flowers and have frequent contact with peoples and farms, thus increasing the risk of spillover of bat viruses to domestic animals and humans. keywords: batcov; bats; gccdc1; hku9; sequences; species; viruses cache: cord-316343-u1uup5da.txt plain text: cord-316343-u1uup5da.txt item: #73 of 99 id: cord-317244-4su5on6s author: Maganga, Gael D. title: Identification of an Unclassified Paramyxovirus in Coleura afra: A Potential Case of Host Specificity date: 2014-12-31 words: 3483 flesch: 45 summary: A new mouse paramyxovirus (J virus) Isolation and molecular characterization of a novel cytopathogenic paramyxovirus from tree shrews Complete genome sequence of a novel paramyxovirus, Tailam virus, discovered in Sikkim rats Identification and phylogenetic comparison of Salem virus, a novel paramyxovirus of horses Reproduction and nutritional stress are risk factors for Hendra virus infection in little red flying foxes Bats host major mammalian paramyxoviruses Encephalitis caused by a lyssavirus in fruit bats in Australia Airborne transmission of lyssaviruses Rabies in nonhematophagous bats Guidelines of the American Society of Mammalogists for the use of wild mammals in research Ecological and behavioral methods for the study of bats Sensitive and broadly reactive reverse transcription-PCR assays to detect novel paramyxoviruses Marburg virus infection detected in a common African bat Newly discovered ebola virus associated with hemorrhagic Fever outbreak in Uganda Basic local alignment search tool MEGA5: Molecular Evolutionary Genetics Analysis using Maximum Likelihood, Evolutionary Distance and Maximum Parsimony Methods MRBAYES: Bayesian inference of phylogenetic trees Isolation of Genetically Diverse Marburg Viruses from Egyptian Fruit Bats Studies of Reservoir Hosts for Marburg Virus Genomic characterizations of bat coronaviruses (1A, 1B and HKU8) and evidence for co-infections in Miniopterus bats Isolation of Hendra virus from pteropid bats: a natural reservoir of Hendra virus Bats are natural reservoirs of SARS-like coronaviruses Bats: important reservoir hosts of emerging viruses Novel astroviruses in insectivorous bats Bat white-nose syndrome: an emerging fungal pathogen? Inoculation of bats with European Geomyces destructans supports the novel pathogen hypothesis for the origin of white-nose syndrome Pathogenesis studies with Australian bat lyssavirus in grey-headed flying foxes (Pteropus poliocephalus) Bats and Lyssaviruses Discovery of an Ebolavirus-Like Filovirus in Europe Nipah virus infection in bats (Order Chiroptera) in Peninsular Malaysia Fruit bats as reservoirs of Ebola virus Is Marburg Virus Enzootic in Gabon? Bats as a continuing source of emerging infections in humans Risk factor for Nipah virus encephalitis in Bangladesh Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats Paramyxovirus and Pneumovirus diseases of animals and birds: comparatives aspects and diagnosis Dionisia bunoi n. g. n. sp., Haemoproteidae parasite du microchiroptè re Hipposideros cyclops au Gabon The chiropteran haemosporidian Polychromophilus melanipherus: A worldwide species complex restricted to the family Many authors suggested that persistence in the absence of pathology or disease appears to be a common characteristic of bat viruses in their natural host population [28, 29] . keywords: afra; bats; belpv; host; paramyxovirus; pcr; rna; species; virus; viruses cache: cord-317244-4su5on6s.txt plain text: cord-317244-4su5on6s.txt item: #74 of 99 id: cord-317813-sisfxdso author: Banskar, Sunil title: Microbiome analysis reveals the abundance of bacterial pathogens in Rousettus leschenaultii guano date: 2016-11-15 words: 6583 flesch: 41 summary: The beta diversity analysis using the Jaccard distance revealed that the CGS and the composite guano contained different bacterial communities which in turn were different from the rest of fresh guano samples (Fig. 7 ). In conclusion, the present study revealed that each gram of R. leschenaultii's guano contains millions of bacteria, belonging to hundreds of different bacterial species, some of which can be potentially pathogenic to humans. keywords: bacteria; bat; bats; coli; communities; gene; guano; ion; isolates; microbiome; pathogens; sequencing; species; study; torrent cache: cord-317813-sisfxdso.txt plain text: cord-317813-sisfxdso.txt item: #75 of 99 id: cord-318080-cmx3q2sc author: Amoroso, Maria Grazia title: Detection and phylogenetic characterization of astroviruses in insectivorous bats from Central‐Southern Italy date: 2018-06-12 words: 2875 flesch: 33 summary: The potential zoonotic risks associated with bats have attracted the attention of researchers, mostly after the discovery of SARS-like and MERS-like CoVs (two coronaviruses highly pathogenic for humans) in European bat species, although the zoonotic risks posed by bat viruses, likely very limited, should be assessed more properly (Kohl & Kurth, 2014) , in large structured studies. • Strains of astrovirus identified revealed a high degree of genetic diversity, not related to bat species. keywords: astrovirus; bats; detection; et al; human; italy; species; viruses cache: cord-318080-cmx3q2sc.txt plain text: cord-318080-cmx3q2sc.txt item: #76 of 99 id: cord-323307-nu9ib62h author: Dong, Dong title: The genomes of two bat species with long constant frequency echolocation calls date: 2016-10-26 words: 7643 flesch: 44 summary: Our result showed more visual perception genes have become pseudogenes in rhinolophoid bats, and it is reasonable to speculate that some visual perception gene may have undergone relaxed natural selection in echolocating bats. The result based on nucleotide data was in line with previous analysis that bats are a sister group to odd-toed ungulates, whereas the result based on amino acid data supported that bat bats are sister group to the Fereuungulata (Carnivores + Perissodactyla + Cetartiodactyla). keywords: bats; et al; evolution; genes; genome; hearing; horseshoe; leaf; result; rhinolophoid; sequences; species; substitutions; supplementary cache: cord-323307-nu9ib62h.txt plain text: cord-323307-nu9ib62h.txt item: #77 of 99 id: cord-324295-9c1zxjng author: Bonilla-Aldana, D. Katterine title: Bats in Ecosystems and their Wide Spectrum of Viral Infectious Threats: SARS-CoV-2 and other emerging viruses date: 2020-08-20 words: 3771 flesch: 40 summary: A study detected a high seroprevalence of antibodies against Marburg virus in fruit bats in South Africa, with a 19.1% seroconversion rate in recaptured bats 24 ; Another study detected MARV genome in bats captured in Zambia 25 ; and a posterior serosurvey identified filovirus-specific immunoglobulin G antibodies in 71 out of 748 serum samples collected from migratory fruit bats 26 . Multiple studies point at bats of the genus Myotis as the main reservoir for Ebola virus given that these bats carry a copy of viral gene VP35 (Table 3) Studies in Africa analyzed 4,022 blood samples from bats, detecting antibodies against Ebola virus in one genus of insectivorous bats and six species of fruit bats 29 . keywords: bats; encephalitis; fruit; humans; rabies; species; study; table; transmission; virus; viruses cache: cord-324295-9c1zxjng.txt plain text: cord-324295-9c1zxjng.txt item: #78 of 99 id: cord-324324-8ybfiz8f author: Decaro, Nicola title: Novel human coronavirus (SARS-CoV-2): A lesson from animal coronaviruses date: 2020-04-14 words: 14950 flesch: 34 summary: After 2002-2003 SARS epidemic, the renovated interest in HCoVs allowed the discovery of two additional viruses, the alphacoronavirus HCoV-NL63 and the betacoronavirus HCoV-HKU1, derived from bats and rodents, respectively (Tao et al., 2017) . NL63 (Tao et al., 2017) . keywords: animals; avian; bats; betacoronavirus; canine; ccov; china; coronavirus; cov; cov-2; covs; disease; enteric; et al; gene; genome; genus; host; human; ibv; infection; mers; novel; origin; protein; recombination; sars; species; strains; subgenus; syndrome; viruses; wild cache: cord-324324-8ybfiz8f.txt plain text: cord-324324-8ybfiz8f.txt item: #79 of 99 id: cord-327534-f2wvh6la author: Zhou, Peng title: IRF7 in the Australian Black Flying Fox, Pteropus alecto: Evidence for a Unique Expression Pattern and Functional Conservation date: 2014-08-06 words: 7755 flesch: 48 summary: Pictures show co-localisation of bat IRF7 or bat IRF3 with bat MyD88 in PaKiT03 cells and human IRF7 or human IRF3 with human MyD88 in HEK293T cells. Sequence differences in the MyD88 binding domain of bat and human IRF7 led to the hypothesis that there may be functional differences in the activation of bat IRF7 and the regulation of the IFN response that may contribute to the ability of bats to resist the clinical outcomes of viral infection. keywords: alecto; bat; bats; binding; cells; expression; figure; human; ifn; immune; irf3; irf7; myd88; promoter; response cache: cord-327534-f2wvh6la.txt plain text: cord-327534-f2wvh6la.txt item: #80 of 99 id: cord-329050-vzsy6xw1 author: Nabi, Ghulam title: Bats and birds as viral reservoirs: A physiological and ecological perspective date: 2020-09-22 words: 5063 flesch: 33 summary: Such migrations allow bat viruses, such as CoVs, the rabies virus, the Hendra, and Nipah viruses, to spread over long distances (Calisher et al., 2006) . This coexistence could allow the mixing of bats and birds viruses for the generation of recombinant, novel mutant, or reassortment of RNA viruses Perrella et al., 2020) . keywords: avian; bats; birds; et al; evolution; flight; humans; influenza; mammals; size; species; viruses; wild cache: cord-329050-vzsy6xw1.txt plain text: cord-329050-vzsy6xw1.txt item: #81 of 99 id: cord-329617-gzivtsho author: Lee, Albert K. title: De novo transcriptome reconstruction and annotation of the Egyptian rousette bat date: 2015-12-07 words: 5061 flesch: 49 summary: In other bat transcriptomes, such as P. alecto and A. jamaicensis, coverage of NK cellrelated genes was more sparse than that of other mammals [32, 33] . Interestingly, bats have recently come to the forefront of zoonotic disease research with vast number of pathogens identified in a wide variety of bat species [2] . keywords: aegyptiacus; assembly; bat; bats; contigs; expression; fig; gene; host; species; transcriptome; transcripts; virus cache: cord-329617-gzivtsho.txt plain text: cord-329617-gzivtsho.txt item: #82 of 99 id: cord-332088-5c77h0of author: Beena, V. title: Emerging horizon for bat borne viral zoonoses date: 2019-10-26 words: 4569 flesch: 44 summary: Recent database on bat viruses from 69 countries worldwide comprises more than 4100 bat-associated animal viruses belonging to 23 viridae detected in 196 bat species [6] . Along with detection and characterization of bat born viruses, the pathology associated with these viruses in the host and the environmental factors which trigger these virus spills over will be found helpful in preventing epidemic. keywords: bats; china; fruit; humans; india; nipha; novel; outbreak; pteropus; species; transmission; virus; viruses cache: cord-332088-5c77h0of.txt plain text: cord-332088-5c77h0of.txt item: #83 of 99 id: cord-333317-oai67igl author: Efremova, Agrafena title: Biomarkers of Browning in Cold Exposed Siberian Adults date: 2020-07-22 words: 4649 flesch: 43 summary: The non-parametric ANCOVA was also applied to evaluate the effect of the number of cold-exposure hours on the distribution of each marker and biochemical variables in cold exposed subjects, using BMI as covariate. In our study, we could not detect differences in the PBMC expression of CPT1A4, SCL27, and PRDM16 comparing cold exposed individuals to controls. keywords: adipose; bat; brown; browning; cold; exposure; expression; group; pbmc; study; subjects cache: cord-333317-oai67igl.txt plain text: cord-333317-oai67igl.txt item: #84 of 99 id: cord-333914-c150ki1n author: Koba, Ryota title: Identification and characterization of a novel bat polyomavirus in Japan date: 2020-08-20 words: 1687 flesch: 46 summary: The aims of this study were to (i) determine the presence of PyVs in Japanese bats, (ii) characterize the genomic structure of bat PyVs, and (iii) analyze the evolutionary relationships between the bat PyV detected in this study and other known bat PyVs. The nucleotide sequence identity of the genome with those of other bat PyVs was less than 80%. keywords: bat; bats; dna; mfpyv; pyvs; sequences; virus cache: cord-333914-c150ki1n.txt plain text: cord-333914-c150ki1n.txt item: #85 of 99 id: cord-334027-xhfmio7k author: Fagre, Anna C. title: Can Bats Serve as Reservoirs for Arboviruses? date: 2019-03-03 words: 8739 flesch: 36 summary: Parasite Diverse RNA viruses of arthropod origin in the blood of fruit bats suggest a link between bat and arthropod viromes A whole genome perspective on the phylogeny of the plant virus family Tombusviridae Metagenomics reshapes the concepts of RNA virus evolution by revealing extensive horizontal virus transfer Redefining the invertebrate RNA virosphere Deliberate insectivory by the fruit bat Rousettus aegyptiacus Deliberate insectivory by the fruit bat Pteropus poliocephalus by aerial hunting Viral antibody dynamics in a chiropteran host The enhancement of arbovirus transmission and disease by mosquito saliva is associated with modulation of the host immune response Experimental infection of North American birds with the New York 1999 strain of West Nile virus Tools to study pathogen-host interactions in bats Ecosystem services provided by bats Marburgvirus resurgence in Kitaka Mine bat population after extermination attempts Empirical assessment of non-invasive population genetics in bats: Comparison of DNA quality from faecal and tissue samples Empirical evaluation of non-invasive capture-mark-recapture estimation of population size based on a single sampling session Optimizing Viral Discovery in Bats Optimizing non-invasive sampling of an infectious bat virus Experimental Inoculation of Egyptian Rousette Bats (Rousettus aegyptiacus) with Viruses of the Ebolavirus and Marburgvirus Genera Bats have long been suspected as reservoirs for arboviruses [11] , but experimental data that would support a role of bats as reservoir hosts for certain arboviruses remain difficult to collect. keywords: antibodies; arboviruses; arthropod; bats; encephalitis; evidence; experimental; fever; field; fruit; infection; japanese; mosquitoes; reservoir; role; species; studies; study; transmission; viremia; virus; viruses cache: cord-334027-xhfmio7k.txt plain text: cord-334027-xhfmio7k.txt item: #86 of 99 id: cord-334628-axon4jdc author: Lee, Saemi title: Genetic Characteristics of Coronaviruses from Korean Bats in 2016 date: 2017-07-19 words: 3233 flesch: 61 summary: In this study, bat samples (332 oral swabs, 245 fecal samples, 38 urine samples, and 57 bat carcasses) were collected at 33 natural bat habitat sites in South Korea. However, little research has been conducted on bat coronaviruses in South Korea. keywords: bat; bats; coronaviruses; cov; covs; samples; sars; sequences; species cache: cord-334628-axon4jdc.txt plain text: cord-334628-axon4jdc.txt item: #87 of 99 id: cord-338055-2d6n4cve author: Hassan, Sk. Sarif title: A unique view of SARS-CoV-2 through the lens of ORF8 protein date: 2020-08-26 words: 5951 flesch: 45 summary: Chemical and structural properties of ORF8 proteins from different hosts, that is human, bat and pangolin, suggests that the ORF8 of SARS-CoV-2 and Bat RaTG13-CoV are very much closer related than that of Pangolin-CoV. Eighty-seven mutations across unique variants of ORF8 (SARS-CoV-2) are grouped into four classes based on their predicted effects. The web-server 60 'QUARK' was used for prediction of the secondary structure of ORF8 proteins [32, 33] . keywords: amino; bat; cov; cov-2; mutations; orf8; pangolin; protein; sars; sequence cache: cord-338055-2d6n4cve.txt plain text: cord-338055-2d6n4cve.txt item: #88 of 99 id: cord-338400-30vl2hks author: Epstein, Jonathan H. title: Identification of GBV-D, a Novel GB-like Flavivirus from Old World Frugivorous Bats (Pteropus giganteus) in Bangladesh date: 2010-07-01 words: 4667 flesch: 44 summary: Entebbe bat virus was used as an outgroup; distance in substitutions per site is indicated by scale bars; percent bootstrap support for values greater than 85% is indicated at respective nodes. Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0 Full-length human immunodeficiency virus type 1 genomes from subtype Cinfected seroconverters in India, with evidence of intersubtype recombination Flavivirus genome organization, expression, and replication Processing in the Hepatitis-C virus E2-N2 region -identification of P7 and 2 Distinct E2-specific products with different C-termini Hepatitis-C virus glycoprotein E2 products with different C-termini Signal peptide cleavage and internal targeting signals direct the hepatitis C virus p7 protein to distinct intracellular membranes Characterization of GB virus B polyprotein processing reveals the existence of a novel 13-kDa protein with partial homology to hepatitis C virus p7 protein Functional analyses of GB virus B p13 protein: Development of a recombinant GB virus B hepatitis virus with a p7 protein Hepatitis G virus encodes protease activities which can effect processing of the virus putative nonstructural proteins The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymerases The phylogeny of RNA-dependent RNA polymerases of positive-strand RNA viruses Identification of 4 conserved motifs among the RNA-dependent polymerase encoding elements Rift-Valley Fever virus L-segment -correction of the sequence and possible functional role of newly identified regions conserved in RNA-dependent polymerases Phosphorylation of hepatitis C virus NS5A nonstructural protein: A new paradigm for phosphorylation-dependent viral RNA replication Src homology 3 domain of hepatitis C virus NS5A protein interacts with Bin1 and is important for apoptosis and infectivity How hepatitis C virus counteracts the interferon response: The jury is still out on NS5A NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling RNA translocation and unwinding mechanism of HCVNS3 helicase and its coordination by ATP GB virus B and hepatitis C virus NS3 serine proteases share substrate specificity The NS3/4A proteinase of the hepatitis C virus: unravelling structure and function of an unusual enzyme and a prime target for antiviral therapy Molecular and serologic analysis in the transmission of the GB hepatitis agents Diagnosis and monitoring of hepatic injury. keywords: bangladesh; bats; gbv; giganteus; hepatitis; humans; protein; rna; sequence; serum; transmission; virus; viruses cache: cord-338400-30vl2hks.txt plain text: cord-338400-30vl2hks.txt item: #89 of 99 id: cord-338586-rkrkofri author: Shi, Zhengli title: Bat and virus date: 2010-02-01 words: 3127 flesch: 35 summary: Many studies focus on bat viruses that caused severe domestic and human diseases. Many studies focus on bat viruses that caused severe domestic and human diseases. keywords: bat; bats; et al; human; rabies; sars; virus; viruses cache: cord-338586-rkrkofri.txt plain text: cord-338586-rkrkofri.txt item: #90 of 99 id: cord-342124-jdv17u86 author: Nieto‐Rabiela, Fabiola title: Viral networks and detection of potential zoonotic viruses in bats and rodents: A worldwide analysis date: 2019-06-20 words: 4449 flesch: 45 summary: To address this gap in knowledge, we compared the associative capacity of the host–virus networks in rodents and bats with the identification of those viruses with zoonotic potential. We observed a greater degree of connectivity in bat viruses and more discrete communities in rodents. keywords: bats; community; host; network; nodes; potential; rodents; viruses; zoonotic cache: cord-342124-jdv17u86.txt plain text: cord-342124-jdv17u86.txt item: #91 of 99 id: cord-343206-9tqivs5f author: Pruvot, Mathieu title: Extreme temperature event and mass mortality of insectivorous bats date: 2019-04-29 words: 1620 flesch: 38 summary: It also provides an important opportunity to conduct surveillance of pathogens circulating in bat populations and understand how heatrelated stress may influence the excretion of pathogens hosted by bats. Systematic documentation of bat die-offs related to extreme weather events is necessary to improve understanding of the effect of changing weather patterns on bat populations and the ecosystem services they provide. keywords: bats; cambodia; mortality; species; temperature cache: cord-343206-9tqivs5f.txt plain text: cord-343206-9tqivs5f.txt item: #92 of 99 id: cord-345695-5vi9wibk author: Hicks, Lorin L. title: A statistical approach to white-nose syndrome surveillance monitoring using acoustic data date: 2020-10-22 words: 5499 flesch: 44 summary: We developed a simple and repeatable statistical modeling approach for WNS surveillance monitoring with bat activity data collected from a broad geographic and temporal scale prior to known occurrence of WNS in the Intermountain West. We investigated relationships among bat activity, ambient temperatures, and season prior to presence of WNS across forested sites of Montana, USA where WNS was not known to occur. keywords: activity; bat; bats; data; forest; model; monitoring; north; sites; species; temperature; winter; wns; year cache: cord-345695-5vi9wibk.txt plain text: cord-345695-5vi9wibk.txt item: #93 of 99 id: cord-347532-n51qv9pp author: Wacharapluesadee, Supaporn title: Group C Betacoronavirus in Bat Guano Fertilizer, Thailand date: 2013-08-17 words: 1194 flesch: 38 summary: To assess pathogens in bat guano, we examined bat guano from a cave in the Khao Chong Phran Non-hunting Area (KCP-NHA) in Ratchaburi Province, Thailand, where bat guano was sold as agricultural fertilizer, for the presence of NiV, CoV, and H. capsulatum fungi. To detect H. capsulatum and other fungi, we extracted genomic DNA directly from bat guano by using the silica-guanidine thiocyanate protocol, NucliSense Isolation Reagent (bioMérieux, Boxtel, the Netherlands), according to the manufacturer's protocol. keywords: bat; bats; cov; guano; pcr; rna cache: cord-347532-n51qv9pp.txt plain text: cord-347532-n51qv9pp.txt item: #94 of 99 id: cord-350286-n7ylgqfu author: Giri, Rajanish title: When Darkness Becomes a Ray of Light in the Dark Times: Understanding the COVID-19 via the Comparative Analysis of the Dark Proteomes of SARS-CoV-2, Human SARS and Bat SARS-Like Coronaviruses date: 2020-04-03 words: 15857 flesch: 51 summary: Evaluation of intrinsic disorder in non-structural proteins of Bat CoV. Table 7 : Predicted MoRF residues in Human SARS proteins. Supplementary Table 10 : Predicted nucleotide-binding residues in Human SARS proteins. keywords: analysis; bat cov; binding; coronavirus; cov; cov-2; disorder; domain; figure; human; mean; protein; regions; residues; rna; sars; sars cov; sequence; structure; syndrome; table; terminal; viral; viruses cache: cord-350286-n7ylgqfu.txt plain text: cord-350286-n7ylgqfu.txt item: #95 of 99 id: cord-352361-jh31omg2 author: Nobach, Daniel title: No evidence for European bats serving as reservoir for Borna disease virus 1 or other known mammalian orthobornaviruses date: 2020-01-30 words: 3760 flesch: 37 summary: Spiking of bat RNA with serial dilutions of various orthobornavirus-RNA demonstrated the detection limit of 5000 orthobornavirus copies in 660 ng RNA. Although the bicolored white-toothed shrew has been identified as indigenous reservoir of BoDV-1, other potential reservoirs or animal carriers are still unknown so that further investigations of small mammals including bat species are urgently needed. keywords: bats; bodv-1; control; disease; orthobornavirus; rna; species; virus; viruses cache: cord-352361-jh31omg2.txt plain text: cord-352361-jh31omg2.txt item: #96 of 99 id: cord-352563-yb446bap author: Li, Ya title: Bat adeno-associated viruses as gene therapy vectors with the potential to evade human neutralizing antibodies date: 2019-05-20 words: 6478 flesch: 48 summary: To produce bat AAV vectors for additional studies, we employed the pseudotyping strategy. The pseudotyping strategy was successfully applied to the production of bat AAV vectors to investigate their transduction and immunological properties. keywords: 09yn; 10hb; aav; aav2; aavs; bat; bat aav; capsid; gene; human; muscle; transduction; vector cache: cord-352563-yb446bap.txt plain text: cord-352563-yb446bap.txt item: #97 of 99 id: cord-354738-4rxradwz author: Kohl, Claudia title: European Bats as Carriers of Viruses with Zoonotic Potential date: 2014-08-13 words: 4799 flesch: 45 summary: Especially the high-risk occupational groups (i.e., bat workers, bat carers in bat bat hospitals) are at increased risk. [9] [10] , while hardly anything is known about human-pathogenicity of European bat viruses apart from lyssaviruses. keywords: bat; bats; cov; european; human; lyssavirus; mers; novel; species; studies; viruses; zoonotic cache: cord-354738-4rxradwz.txt plain text: cord-354738-4rxradwz.txt item: #98 of 99 id: cord-355075-ieb35upi author: Papenfuss, Anthony T title: The immune gene repertoire of an important viral reservoir, the Australian black flying fox date: 2012-06-20 words: 8959 flesch: 48 summary: The GO classification demonstrates that a diverse range of genes were identified in each of our two datasets providing a broad survey of bat genes. We have also begun to identify some of the genes involved in immune responses in this species and carry out functional studies in bat cells keywords: alecto; antiviral; bat; bats; cells; class; contigs; datasets; genes; immune; mammals; mhc; protein; receptors; sequences; species; thymus; transcriptome; transcripts; viruses cache: cord-355075-ieb35upi.txt plain text: cord-355075-ieb35upi.txt item: #99 of 99 id: cord-355737-o0y4rn0z author: Ng, Melinda title: Filovirus receptor NPC1 contributes to species-specific patterns of ebolavirus susceptibility in bats date: 2015-12-23 words: 8969 flesch: 40 summary: Rather, we used a diverse set of bat NPC1 sequences, only one of which is from African straw-colored fruit bats, to show that a number of codons, including residue 502, have evolved under recurrent positive selection. In this study, we uncover a pattern of virus and host species specificity in the filovirus susceptibility of bat cells, which can be explained by eLife digest Ebola virus and other filoviruses can cause devastating diseases in humans and other apes. keywords: bats; binding; cells; data; domain; ebola; ebov; ehnpc1; entry; et al; figure; filovirus; fruit; fruit bat; host; human; infection; npc1; receptor; sequence; species; straw; virus cache: cord-355737-o0y4rn0z.txt plain text: cord-355737-o0y4rn0z.txt