item: #1 of 7819
          id: cord-009749-mdkuf5bd
      author: Dobran, Mauro
       title: Letter to the editor by Dobran Mauro, Paracino Riccardo, and Iacoangeli Maurizio regarding “Neurosurgery during the COVID-19 pandemic: update from Lombardy, northern Italy.” Zoia C, Bongetta D, Veiceschi P, Cenzato M, Di Meco F, Locatelli D, Boeris D, Fontanella MM. Acta Neurochir (Wien). 2020 Mar 28. doi: 10.1007/s00701-020-04305-w
        date: 2020-04-17
       words: 722
      flesch: 39
     summary: In our hospital to concentrate resources on COVID-19 emergency, the non-urgent activities were suspended and each department provided some of its doctors and nurses to reinforce the COVID-19 staff. To face the danger of contagion even in our neurosurgical department, measures have been implemented such as the suspension of all scheduled surgical activity with the exception of class A for oncologic patients, maintenance of neurosurgical emergencies (cerebral hemorrhages, hydrocephalus, tumors with intracranial hypertension, spinal cord compression, and traumatic cranial and spinal), and the urgent neurosurgical visit or the scheduled ones within 10 days.
    keywords: covid-19; italy; patients
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        item: #2 of 7819
          id: cord-010540-0zkc5w74
      author: Lei, Pinggui
       title: Multiple parameters required for diagnosis of COVID-19 in clinical practice
        date: 2020-03-19
       words: 707
      flesch: 40
     summary: Significant statistical differences were observed in lymphocyte percentage decreased and C-reactive protein elevated (all P = 0.015) in the patients with COVID-19 infection between initial positive chest CT results (10/14) and negative chest CT results (4/14). We would like to share our opinions for diagnostic approach of COVID-19 infection, the diagnostic approach for COVID-19 infection should be made comprehensive analysis.
    keywords: covid-19; infection
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        item: #3 of 7819
          id: cord-010547-zhw8vh3e
      author: Vaishya, Raju
       title: Artificial Intelligence (AI) applications for COVID-19 pandemic
        date: 2020-04-14
       words: 1368
      flesch: 46
     summary: AI is not only helpful in the treatment of COVID-19 infected patients but also for their proper health monitoring. CT An analysis of pathology knowledge and decision making for the development of artificial intelligence-based consulting systems Contentious issues and evolving concepts in the clinical presentation and management of patients with COVID-19 infection with reference to use of therapeutic and other drugs used in Co-morbid diseases (Hypertension, diabetes etc.).
    keywords: covid-19; help; patients
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        item: #4 of 7819
          id: cord-010585-hasoaa0k
      author: Szekely, Yishay
       title: Chloroquine-induced torsade de pointes in a COVID-19 patient
        date: 2020-05-05
       words: 1338
      flesch: 46
     summary: The arrhythmogenic cardiotoxicity of the quinoline and structurally related antimalarial drugs: a systematic review Risk Categories for Drugs that Prolong QT & induce Torsades de Pointes (TdP) World Health Organization-Malaria Policy Advisory Committee Meeting The QT interval in patients with COVID-19 treated with hydroxychloroquine and azithromycin Chloroquine diphosphate in two different dosages as adjunctive therapy of hospitalized patients with severe respiratory syndrome in the context of coronavirus (SARS-CoV-2) infection: Preliminary safety results of a randomized, double-blinded, phase IIb clinical trial (CloroCovid-19 Study) Development and validation of a risk score to predict QT interval prolongation in hospitalized patients Cardiac arrhythmia considerations of hormone cancer therapies Urgent Guidance for Navigating and Circumventing the QTc-Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for Coronavirus Disease 19 (COVID-19) SARS-CoV-2, COVID-19 and inherited arrhythmia syndromes Ventricular arrhythmia risk due to hydroxychloroquine-azithromycin treatment for COVID-19 Poppas Athena, Russo Andrea M. Considerations for Drug Interactions on QTc in Exploratory COVID-19 Chloroquine for SARS-CoV-2: Implications of Its Unique Pharmacokinetic and Safety Properties This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Clinicians should monitor COVID-19 patients when treating them with chloroquine or other QT-prolonging drugs, with special attention to females, patients with structural heart disease, baseline QT interval on ECG, concomitant use of other QT-prolonging medications, potassium or magnesium abnormalities and bradycardia.
    keywords: chloroquine; covid-19; tdp
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        item: #5 of 7819
          id: cord-010658-67k8pthy
      author: Bernard, Andie
       title: PC-FACS May 2020 for July 2020 Issue
        date: 2020-05-07
       words: 1927
      flesch: 39
     summary: Furthermore, nonbeneficial/unwanted care puts other patients, family, and healthcare workers at greater transmission risk. As of March 17, mortality was 67%, 24% of patients have remained critically ill, and 9.5% have been discharged from the ICU.
    keywords: care; covid-19; families; pandemic; patients
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        item: #6 of 7819
          id: cord-011402-sk4tgdf8
      author: Low, Tze-Yi
       title: Restructuring the surgical service during the COVID-19 pandemic: Experience from a tertiary institution in Singapore
        date: 2020-05-15
       words: 1184
      flesch: 49
     summary: There were 338 reported incidents for surgical patients from February to March 2020, compared to 397 for the same period in 2019 (Fig. 2d) . This is a fine balance as prolonged suspension of elective surgical care is likely result in additional patient morbidity and mortality from delayed diagnosis and treatment.
    keywords: covid-19; pandemic; patients; period
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        item: #7 of 7819
          id: cord-011413-yv4x8viu
      author: Shekar, Kiran
       title: Extracorporeal Life Support Organization Coronavirus Disease 2019 Interim Guidelines: A Consensus Document from an International Group of Interdisciplinary Extracorporeal Membrane Oxygenation Providers
        date: 2020-05-12
       words: 7481
      flesch: 35
     summary: Adhere to local or institutional policies on PPE use for COVID-19 patients ECMO initiation, and decannulation and bedside care should be performed with appropriate airborne plus contact precaution PPE including N95/FFP2 mask, gown, cap, eye protection (e.g., goggles or visor) ECMO initiation, decannulation, and all AGPs be performed with PPE and N95 masks or PAPR with full contact precautions Although caring for COVID-19 ECMO patients wear appropriate PPE including N95/FFP2 masks, gowns, cap, eye protectors (e.g., goggles, visor) and follow contact precautions For procedures in which splashing or aerosol generation is anticipated, a higher level of protection (e.g., gown at AAMI level 3 or equivalent) should be considered 18 Labor-intensive procedures (e.g., mobilization, prone positioning, transport) carry significant risk of infection control breach to staff. • ECMO programs should keep a manifest of all team members who are trained to care for ECMO patients.
    keywords: cannulation; capacity; care; centers; covid-19; ecmo; elso; extracorporeal; guidelines; hospital; membrane; oxygenation; pandemic; patients; ppe; risk; support; use
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        item: #8 of 7819
          id: cord-011424-d4pswmxa
      author: Naidich, Jason J.
       title: Impact of the Coronavirus Disease 2019 (COVID-19) Pandemic on Imaging Case Volumes
        date: 2020-05-16
       words: 3458
      flesch: 48
     summary: As a consequence of public policy, financial hardship, and patient fear, many radiology departments have experienced a rapid decline in imaging case volumes. The purpose of this study was to evaluate the impact of the COVID-19 pandemic on imaging case volumes using real-world data from a large health care institution.
    keywords: covid-19; imaging; locations; patient; volumes; weeks
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        item: #9 of 7819
          id: cord-011482-c2jdjh2u
      author: Riccardo, Bertolo
       title: Re: Reflections on the COVID-19 Pandemic
        date: 2020-04-23
       words: 246
      flesch: 46
     summary: Reflections on the COVID-19 Pandemic Impact of the COVID-19 Pandemic on the Urologist's clinical practice in Brazil: a management guideline proposal for low-and middle-income countries during the crisis period Robotic Urology Section) guidelines during COVID-19 emergency. key: cord-011482-c2jdjh2u authors: Riccardo, Bertolo; Cipriani, Chiara; Vittori, Matteo; Bove, Pierluigi title: Re: Reflections on the COVID-19 Pandemic date: 2020-04-23 journal: Int Braz J Urol DOI: 10.1590/s1677-5538.ibju.2020.0306 sha: doc_id: 11482 cord_uid: c2jdjh2u nan To date, real-time polymerase chain reaction in respiratory samples is the gold standard method for diagnosing COVID-19 (6) .
    keywords: covid-19; test
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        item: #10 of 7819
          id: cord-011620-f3uw74w7
      author: Tokuç, Burcu
       title: Medical Education in Turkey in Time of COVID-19
        date: 2020-06-01
       words: 1222
      flesch: 44
     summary: In the last 50 years, the reduction of infectious diseases against chronic diseases, the ease of treatment of infectious diseases with the use of antibiotics has also directed medical education and the curriculum of medical schools to the diagnosis and treatment of chronic diseases in disease research, and both drug and vaccine development studies. Consequently, community oriented and community based medical education and social accountability of medical schools should be implemented to all stages of medical education (7) .
    keywords: covid-19; education; medical
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        item: #11 of 7819
          id: cord-011637-1ojind95
      author: Roffi, Marco
       title: The Obstacle Course of Reperfusion for ST-Segment–Elevation Myocardial Infarction in the COVID-19 Pandemic
        date: 2020-04-21
       words: 1421
      flesch: 38
     summary: Spoke centers may have been converted to COVID hospitals, may be more restrictive in transferring patients who have STEMI for primary PCI, and may adopt fibrinolytic treatment without subsequent systematic referral for angiography. The regional STEMI network was quickly changed into a model of macrohubs to concentrate personnel and urgent activities, such as primary PCI for STEMI or interventional stroke management, while expanding health resources for patients with COVID-19 in all remaining hospitals.
    keywords: covid-19; patients; pci; stemi
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        item: #12 of 7819
          id: cord-011656-zln7zmn9
      author: Subedi, Asish
       title: Medical Ethics Versus Healthcare Workers’ Rights: Fight-or-Flee Response
        date: 2020-06-16
       words: 861
      flesch: 59
     summary: This report highlights the importance of psychological well-being of health care workers involved during the COVID-19 tsunami. To overcome the mental stress, the government should provide social securities and incentives to health care workers, and moral support to reassure how important we are to the country and the sacrifices we are doing at this crisis.
    keywords: care; covid-19; ppes
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        item: #13 of 7819
          id: cord-011663-3ggah1y1
      author: Haider, Najmul
       title: Response to ‘Evaluation of modelling study shows limits of COVID-19 importing risk simulations in sub-Saharan Africa’ (Epidemiology and Infection – HYG-LE-10513-May-20)
        date: 2020-06-10
       words: 368
      flesch: 42
     summary: key: cord-011663-3ggah1y1 authors: Haider, Najmul; Yavlinsky, Alexei; Kock, Richard title: Response to ‘Evaluation of modelling study shows limits of COVID-19 importing risk simulations in sub-Saharan Africa’ (Epidemiology and Infection – HYG-LE-10513-May-20) date: 2020-06-10 journal: Epidemiol Infect DOI: 10.1017/s0950268820001211 sha: doc_id: 11663 cord_uid: 3ggah1y1 nan Response to 'Evaluation of modelling study shows limits of COVID-19 importing risk simulations in sub-Saharan Africa' ( Evaluation of modelling study shows limits of COVID-19 importing risk simulations in sub-Saharan Africa 2020)
    keywords: covid-19
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        item: #14 of 7819
          id: cord-011725-t1jl4cy1
      author: Varma, Niraj
       title: HRS/EHRA/APHRS/LAHRS/ACC/AHA worldwide practice update for telehealth and arrhythmia monitoring during and after a pandemic
        date: 2020-06-11
       words: 3651
      flesch: 30
     summary: In COVID-19 patients receiving prior antiarrhythmic therapy, there should be a thorough consideration of risk vs benefit before initiating any QT-prolonging COVID-19 therapies, especially considering their unproven value. Clinical characteristics of Covid-19 in New York City Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) Transient complete heart block in a patient with critical COVID-19 A young woman presenting with a viral prodrome, palpitations, dizziness, and heart block Cardiac and arrhythmic complications in patients with COVID-19 Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19) Guidance on minimizing risk of drug-induced ventricular arrhythmia during treatment of COVID-19: a statement from the Canadian Heart Rhythm Society How to protect the protectors: 10 lessons to learn for doctors fighting the COVID-19 coronavirus Inpatient use of mobile continuous telemetry for COVID-19 patients treated with hydroxychloroquine and azithromycin ISHNE-HRS expert consensus statement on ambulatory ECG and external cardiac monitoring/telemetry Comparison of QT interval readings in normal sinus rhythm between a smartphone heart monitor and a 12-lead ECG for healthy volunteers and inpatients receiving sotalol or dofetilide A wearable remote monitoring system for the identification of subjects with a prolonged QT interval or at risk for drug-induced long QT syndrome Can smartphone wireless ECGs be used to accurately assess ECG intervals in pediatrics?
    keywords: azithromycin; care; covid-19; ecg; health; hydroxychloroquine; monitoring; patients; qtc; risk
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        item: #15 of 7819
          id: cord-011793-hlktpla4
      author: Rice, Todd W.
       title: In Defense of Evidence-based Medicine for the Treatment of COVID-19 Acute Respiratory Distress Syndrome
        date: 2020-07-17
       words: 1829
      flesch: 32
     summary: n Effective treatment of severe COVID-19 patients with tocilizumab Tissue plasminogen activator (tPA) treatment for COVID-19 associated acute respiratory distress syndrome (ARDS): a case series Evaluating the efficacy and safety of two doses of the polyclonal anti-tumor necrosis factor-a fragment antibody AZD9773 in adult patients with severe sepsis and/or septic shock: randomized, double-blind, placebo-controlled phase IIb study Effect of intravenous interferon b-1a on death and days free from mechanical ventilation among patients with moderate to severe acute respiratory distress syndrome: a randomized clinical trial Randomized clinical trial of activated protein C for the treatment of acute lung injury National Heart, Lung, and Blood Institute ARDS Clinical Trials Network. In Defense of Evidence-based Medicine for the Treatment of COVID-19 Acute Respiratory Distress Syndrome date: 2020-07-17 journal: Ann Am Thorac Soc DOI: 10.1513/annalsats.202004-325ip sha: doc_id: 11793 cord_uid: hlktpla4 nan Severe acute respiratory failure from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) coronavirus disease has challenged intensivists worldwide with both increased severity of illness and quantity of patients.
    keywords: acute; care; covid-19; patients; trials
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        item: #16 of 7819
          id: cord-011808-ev7qv94b
      author: Sfeir, Maroun M
       title: Frontline workers sound the alarm: be always sure you’re right, then go ahead
        date: 2020-06-16
       words: 1399
      flesch: 55
     summary: Social media outlets have been bursting with frustrations and fearful stories from healthcare workers and other frontline workers. 4 Moreover, stressed and overworked healthcare workers shared critical concerns about lack of personal protective equipment (PPE) nationwide.
    keywords: covid-19; healthcare; hospital; workers
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        item: #17 of 7819
          id: cord-011844-eplgwnem
      author: Hooshmandi, Etrat
       title: The Case Is Much More Baffling than We Think
        date: 2020-06-02
       words: 657
      flesch: 49
     summary: Contrary to their conclusion, there are some reports about increased risk of stroke in COVID-19 infection [3] . Considering the anecdotal and unpublished reports of stroke subsequent to COVID-19 infection, at the present time, it is too early to consider the cause and effect, but further prospective and large-volume studies are warranted.
    keywords: covid-19; infection; stroke
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        item: #18 of 7819
          id: cord-012010-5h2ox3hu
      author: Bos, Lieuwe D.J.
       title: Response to “COVID-19 conundrum: Clinical phenotyping based on pathophysiology as a promising approach to guide therapy in a novel illness” and “Strengthening the foundation of the house of CARDS by phenotyping on the fly” and “COVID-19 phenotypes: leading or misleading?”
        date: 2020-08-03
       words: 2154
      flesch: 31
     summary: Further, a recent report from Haudebourg et al. demonstrated no correlation between duration of symptoms and respiratory compliance in COVID-19 patients ( Figure 1a ) We merely disagree with the correspondent's conclusions regarding the prevalence of these theoretical patients based on data from 16 patients [20] , as well as their subsequent recommendations to deviate from safe ventilatory practice for COVID-19 patients based on this limited data.
    keywords: ards; compliance; covid-19; data; patients
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        item: #19 of 7819
          id: cord-012587-h3c9novk
      author: Bos, Lieuwe D. J.
       title: Subphenotyping Acute Respiratory Distress Syndrome in Patients with COVID-19: Consequences for Ventilator Management
        date: 2020-09-17
       words: 1462
      flesch: 44
     summary: Patients with H-type ARDS may benefit from lower tidal volumes and higher positive end-expiratory pressure (PEEP), and patients with L-type ARDS may benefit from higher tidal volumes and lower PEEP (5) . Patients with a nonfocal lung morphology had more parenchymal involvement (P = 0.0065) but did not have lower Crs (P = 0.72) than patients with focal lung morphology.
    keywords: ards; covid-19; lung; patients
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        item: #20 of 7819
          id: cord-012856-53ep0kty
      author: Thyagarajan, Rama
       title: Timing of surgery after recovery from coronavirus disease 2019 (COVID-19) infection
        date: 2020-07-03
       words: 1103
      flesch: 33
     summary: Most concerns with regard to surgery in recovered COVID-19 positive patients are related to the uncertainty of the postsymptomatic infectious period. Specifically, recovered patients should isolate for at least 10 days rather than 7 days after symptom onset and for at least 3 days after recovery.
    keywords: covid-19; patients; surgery
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        item: #21 of 7819
          id: cord-012897-n5ujh4qg
      author: Barrett, Tessa J.
       title: Platelet and Vascular Biomarkers Associate With Thrombosis and Death in Coronavirus Disease
        date: 2020-08-06
       words: 1034
      flesch: 39
     summary: We speculated that in COVID-19, biomarkers of platelet activation are associated with incident thrombosis or death. Thus, we investigated in vivo surrogate biomarkers of platelet activation and vascular inflammation collected in the early phase of COVID-19 hospitalization.
    keywords: covid-19; patients; platelet; thrombosis
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        item: #22 of 7819
          id: cord-012898-1jl6zcwa
      author: Schäfer, Sarah K.
       title: Impact of COVID-19 on Public Mental Health and the Buffering Effect of a Sense of Coherence
        date: 2020-08-18
       words: 3010
      flesch: 47
     summary: Higher pre-outbreak symptom levels were related to smaller changes in SOC levels. Moreover, we consistently identified SOC as a predictor of individual symptom change, with higher SOC levels predicting smaller symptom changes.
    keywords: covid-19; health; levels; outbreak; soc; stress
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        item: #23 of 7819
          id: cord-012903-fdl1d8as
      author: Kundi, Harun
       title: Trends in acute myocardial infarction admissions during the COVID-19 pandemic in Ankara, Turkey
        date: 2020-07-27
       words: 719
      flesch: 45
     summary: Thus, the Center for Disease Control and Prevention suggested the postponement of elective cardiac procedures including percutaneous coronary interventions in all stable patients, to provide enhanced health care in COVID-19 patients (3). Even if all healthcare professionals around the world including cardiologists are focusing on COVID-19 patients and have intense working conditions, every effort should be made by the cardiology communities to provide good quality health and medical care.
    keywords: ami; covid-19; patients
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        item: #24 of 7819
          id: cord-012916-1op8m0pk
      author: Jia, Fei
       title: Using social media to analyze public psychological status during the recovery period of COVID-19 in China
        date: 2020-09-03
       words: 1304
      flesch: 53
     summary: key: cord-012916-1op8m0pk authors: Jia, Fei; Liu, Xiaoguang title: Using social media to analyze public psychological status during the recovery period of COVID-19 in China date: 2020-09-03 journal: J Public Health (Oxf) DOI: 10.1093/pubmed/fdaa152 sha: doc_id: 12916 cord_uid: 1op8m0pk BACKGROUND: During the outbreak, billions of people were eager to get information about COVID-19 through social media. Social media can not only deliver reliable information to the public but can in turn reflect changes in the public’s psychological status.
    keywords: covid-19; media; public
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        item: #25 of 7819
          id: cord-013035-7sfj0czv
      author: Savinelli, Stefano
       title: Reply
        date: 2020-09-20
       words: 1259
      flesch: 31
     summary: On the other hand, the risk of bacterial infection may be higher in the ICU setting, where more frequent use of vascular and other indwelling devices represent a risk for bloodstream infections (BSI), which are also often reported in patients with COVID-19. In this context, perhaps early rather than late administration in COVID-19 ward patients could be of certain value, before the need of intensive care and at the very beginning of inflammatory cascade, based on specific diagnostic criteria that need to be clearly established.
    keywords: covid-19; patients; tocilizumab
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        item: #26 of 7819
          id: cord-013212-lx614fy4
      author: Nobel, Yael R.
       title: Reply to GASTRO-D-20-01179
        date: 2020-10-14
       words: 590
      flesch: 44
     summary: In our study, conducted among outpatients with respiratory symptoms being evaluated for COVID-19 during the height of the pandemic, the presence of gastrointestinal symptoms (diarrhea or nausea/vomiting) was associated with a 70% increased risk of testing positive for SARS-CoV-2. In sum, our study found that the presence of gastrointestinal symptoms (diarrhea with or without nausea/vomiting) predicted a positive test for SARS-CoV-2 among patients with respiratory symptoms at the height of the COVID-19 pandemic.
    keywords: covid-19; symptoms
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        item: #27 of 7819
          id: cord-013269-u1e0kzmm
      author: Cucinotta, Domenico
       title: Primum non nocere (first do no harm). The SARS-CoV-2 pandemic course in oldest in Italy
        date: 2020-05-11
       words: 1603
      flesch: 49
     summary: But the complexity of modern medicine, as well as the great number of professionals taking care of a single problem and of a single patient, have resulted in bad strategy and a great confusion in policymakers, particularly concerning care of older people. Great interest was given to the apex of the pyramid (ICUs) instead of the base (prevention devices, lockdown of health facilities for old people).
    keywords: covid-19; days; homes; patients; use
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        item: #28 of 7819
          id: cord-021146-wdnnjlcw
      author: Jandrić, Petar
       title: Postdigital Research in the Time of Covid-19
        date: 2020-03-21
       words: 2397
      flesch: 49
     summary: Over the centuries, viral pandemics such as the 1918 Spanish flu have been major biological, social, and cultural events. Postdigital viral modernity is equally about biology, culture, and society; in the long run, humanity cannot defend itself from Covid-19 and create a better future without engaging all strata of the society.
    keywords: covid-19; life; pandemic; postdigital; research; viruses
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        item: #29 of 7819
          id: cord-022175-h83aed9u
      author: Zhang, Hui
       title: Consensus on Pre-examination and Triage in Clinic of Dermatology During Outbreak of COVID-19 From Chinese Experts(#)
        date: 2020-03-13
       words: 1412
      flesch: 23
     summary: Considering the most common symptom of coronavirus disease 2019 (COVID-19) is fever, and many kinds of skin diseases are also accompanied by fever, properly carrying out pre-examination and triage for patients with skin lesions and fever has been a practical problem encountered in the hospitals for skin diseases and dermatology clinics in general hospitals. During the fight against the epidemic of COVID-19, properly carrying out pre-examination and triage for patients with skin lesions and fever has been a practical problem encountered in hospitals for skin diseases as well as clinics of dermatology in general hospitals.
    keywords: covid-19; dermatology; fever; skin
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        item: #30 of 7819
          id: cord-022603-rgb409fo
      author: Descatha, A.
       title: Prise en charge en urgence d’un salarié avec suspicion d’une symptomatologie COVID-19
        date: 2020-04-15
       words: 1058
      flesch: 63
     summary: La base des protocoles est la même que celle habituellement mise en place dans les entreprises, mais adaptée à la situation particulière du COVID-19 qui a été considérée comme un motif de recours en lui-même Le suivi par le service de santé au travail est essentiel.
    keywords: les
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        item: #31 of 7819
          id: cord-023038-p9w9fwak
      author: Fang, Mengjie
       title: CT radiomics can help screen the Coronavirus disease 2019 (COVID-19): a preliminary study
        date: 2020-04-15
       words: 2548
      flesch: 44
     summary: Unsupervised clustering of patients (n = 75) and radiomics features (n = 77) reveal clusters of patients with similar radiomic expression patterns. Besides, 2D ROI and 2D radiomic features are used during our analysis.
    keywords: covid-19; features; patients; pneumonia; radiomic; set
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        item: #32 of 7819
          id: cord-023483-owgs4syo
      author: Marshall, John L
       title: Colorectal cancer care in the age of coronavirus: strategies to reduce risk and maintain benefit
        date: 2020-04-16
       words: 2838
      flesch: 41
     summary: [3] that cancer patients are at increased risk of severe illness if they are to develop a COVID-19 infection and there is even some evidence to suggest that healthcare providers are at increased risk, possibly due to exposure to larger viral loads and repeated exposure [4, 5] . A novel coronavirus from patients with pneumonia in China Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Cancer care during the spread of coronavirus disease 2019 (COVID-19) in Italy: young oncologists'perspective Epidemiology of COVID-19 in a long-term care facility in King County Viral dynamics in mild and severe cases of COVID-19 International guidelines on radiation therapy for breast cancer during the COVID-19 pandemic Recommendations for prioritization, treatment, and triage of breast cancer patients during the COVID-19 pandemic: executive summary (2020).
    keywords: cancer; covid-19; months; patients; risk; treatment
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        item: #33 of 7819
          id: cord-023988-u60l07jv
      author: Bao, Yinyin
       title: Snapshots of Life—Early Career Materials Scientists Managing in the Midst of a Pandemic
        date: 2020-04-23
       words: 4649
      flesch: 60
     summary: Although with less productivity, fortunately I have more time to teach my daughter mathematics, read story books for my son, make handicrafts with them, and have other fun. While lots of my friends and colleagues returned home to spend more time with their families at the beginning of the crisis, a mixture of logic and reflection advised me to stay home for the greater good, despite my family's call to come back.
    keywords: covid-19; group; home; lab; online; pandemic; research; students; time; working
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        item: #34 of 7819
          id: cord-024002-ag5by3k2
      author: Sánchez-Recalde, Ángel
       title: COVID-19 y shock cardiogénico: diferentes formas de presentación cardiovascular con alta mortalidad
        date: 2020-04-27
       words: 1342
      flesch: 35
     summary: La tabla 1 muestra las características clínicas, analíticas y de imagen, el tratamiento y la evolución de los pacientes. Características clínicas, analíticas y de imagen, tratamientos y evolución de los 4 pacientes complicados con shock cardiogénico
    keywords: caso; con; covid-19; del; por; que; shock
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        item: #35 of 7819
          id: cord-024005-rsnf1ib0
      author: Paquet, Mireille
       title: COVID-19 as a Complex Intergovernmental Problem
        date: 2020-04-14
       words: 1858
      flesch: 36
     summary: These problems create barriers to collaboration because they call into question the existing power equilibriums and dominant narratives about how to work together and share responsibilities within intergovernmental systems. Understanding how intergovernmental systems are influencing policy responses to COVID-19 is critical.
    keywords: canada; covid-19; policy; problem
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        item: #36 of 7819
          id: cord-024073-243addff
      author: Richards, Guy
       title: COVID-19 and the Rationale for Pharmacotherapy: A South African Perspective
        date: 2020-04-17
       words: 3411
      flesch: 34
     summary: FDA authorize s widespread use of unproven drugs to treat coronavirus, saying possible benefit outweighs risk Advisory on the use of hydroxy-chloroquine as prophylaxis for SARS-Cov 2 infection Extraordinary GU rich-rich single strand RNA identified from SARS coronavirus contributes an excessive innate immune response Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel middle east respiratory syndrome coronavirus: implications for pathogenesis and treatment Aberrant pathogenic GM-CSF + T cells and inflammatory CD14+CD16+ monocytes in severe pulmonary syndrome patients of a new coronavirus Effective treatment of severe COVID-19 patients with tocilizumab National Health Commission (NHC) of the People's Republic of China. Coronavirus infectionsmore than just the common cold Epidemic models of contact tracing: systematic review of transmission studies of severe acute respiratory syndrome and Middle East respiratory syndrome Rapid response: Re: preventing a Covid-19 pandemic -is there a magic bullet to save COVID-19 patients?
    keywords: clinical; coronavirus; covid-19; disease; mortality; patients; study; therapy; treatment
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        item: #37 of 7819
          id: cord-024076-q9fw7ch1
      author: Manga, Pravin
       title: Should ACE Inhibitors and Angiotensin Receptor Blockers Be Withdrawn in the Current Setting of COVID-19 Infection?
        date: 2020-04-17
       words: 1865
      flesch: 28
     summary: key: cord-024076-q9fw7ch1 authors: Manga, Pravin title: Should ACE Inhibitors and Angiotensin Receptor Blockers Be Withdrawn in the Current Setting of COVID-19 Infection? date: 2020-04-17 journal: nan DOI: 10.18772/26180197.2020.v2nsia4 sha: doc_id: 24076 cord_uid: q9fw7ch1 nan The reports urging caution in the use of ACE inhibitors and ARBs for hypertension, diabetes and cardiovascular disease are based on laboratory data which found that SARS-CoV and COVID-19 virus binds to ACE 2 receptor which is found in the epithelial cells of the lung, kidney, intestine and blood vessels. In some experimental studies with animal models, it has been shown that there is increased expression and activity of ACE 2 in the heart and brain after treatment with ACE inhibitors and ARBs.(7)
    keywords: ace; covid-19; inhibitors; patients
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        item: #38 of 7819
          id: cord-024078-d34e31zd
      author: Baldwin-Ragaven, Laurel
       title: Social Dimensions of COVID-19 in South Africa: A Neglected Element of the Treatment Plan
        date: 2020-04-17
       words: 4351
      flesch: 45
     summary: Institute for Research in the Social Sciences COVID-19 infection prevention and control guidelines for South Africa -draft V1. key: cord-024078-d34e31zd authors: Baldwin-Ragaven, Laurel title: Social Dimensions of COVID-19 in South Africa: A Neglected Element of the Treatment Plan date: 2020-04-17 journal: nan DOI: 10.18772/26180197.2020.v2nsia6 sha: doc_id: 24078 cord_uid: d34e31zd nan Mandela's triumphant release from prison 30 years ago, those halcyon weeks in 2010 when we were hosts to the Soccer World Cup, or more recently Siya Kolisi's diverse team of players overcoming enormous odds to achieve a global rugby victory -the unity and transcendence of the rainbow nation largely have eluded us.
    keywords: africa; covid-19; health; human; life; medical; patients; people; population; south; virus; world
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        item: #39 of 7819
          id: cord-024080-eh3ztsv5
      author: Dheda, Keertan
       title: Diagnosis of COVID-19: Considerations, Controversies and Challenges in South Africa
        date: 2020-04-17
       words: 3958
      flesch: 35
     summary: (6, 7) In early disease, procalcitonin may distinguish COVID-19 from bacterial infections but not from other viral diseases (data are awaited to confirm this supposition). Clinical and laboratory parameters that may suggest viral infection may include pyrexia, acute malaise and myalgia, and lymphopenia.
    keywords: coronavirus; covid-19; disease; infection; patients; pcr; sars; symptoms; testing
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        item: #40 of 7819
          id: cord-024081-19wk56an
      author: Kalla, Ismail S.
       title: COVID-19: The Concept of Herd Immunity – Is It A Strategy for South Africa?
        date: 2020-04-17
       words: 1761
      flesch: 48
     summary: This phased approach may also help us to mitigate against the potential of the 're-emergence phenomenon', where there is a sudden spike in the incidence of new COVID-19 cases (Figure 1).(13,14) Furthermore, in a study of 44,672 confirmed COVID-19 cases of adults and children from China, South Korea, Italy and Spain (as on 11 February 2020), a total of 965 (2.2%) deaths were recoded, with only 1 death in the 10-19-year age group and no deaths in the 0-9-year age group.(9,10)
    keywords: covid-19; herd; immunity; population; south
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        item: #41 of 7819
          id: cord-024130-kgzegwon
      author: Ankita
       title: COVID-19: An Ophthalmological Update
        date: 2020-04-30
       words: 2851
      flesch: 46
     summary: According to a recently published literature on COVID-19 conjunctivitis, tear sample and conjunctival swab are reported to be positive for the novel coronavirus. The treatment of COVID-19 conjunctivitis is an ongoing research (National Institutes of Health 2020).
    keywords: care; conjunctival; conjunctivitis; coronavirus; covid-19; disease; patients
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        item: #42 of 7819
          id: cord-024133-zv0ysi8m
      author: Saxena, Shailendra K.
       title: Current Insight into the Novel Coronavirus Disease 2019 (COVID-19)
        date: 2020-04-30
       words: 2227
      flesch: 39
     summary: pii: eaba9757 Discovering drugs to treat coronavirus disease 2019 (COVID-19) Illinois COVID-19 Investigation Team (2020) First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA Estimated effectiveness of symptom and risk screening to prevent the spread of COVID-19 SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Identification of coronavirus isolated from a patient in Korea with COVID-19 Structural, glycosylation and antigenic variation between 2019 novel coronavirus (2019-nCoV) and SARS coronavirus (SARS-CoV) Molecular immune pathogenesis and diagnosis of COVID-19 Ye F (2020b) Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis Safety and immunogenicity study of 2019-nCoV vaccine (mRNA-1273) to prevent SARS-CoV-2 infection Veesler D (2020) However, extensive measures have been implemented by outstanding public health action to reduce person-to-person transmission of SARS-CoV-2 ( Fig. 1.2 ).
    keywords: coronavirus; cov-2; covid-19; disease; sars
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        item: #43 of 7819
          id: cord-024134-ym7ce5ux
      author: Chawla, Sonam
       title: Preparing for the Perpetual Challenges of Pandemics of Coronavirus Infections with Special Focus on SARS-CoV-2
        date: 2020-04-30
       words: 6816
      flesch: 32
     summary: Grossly, the extent of success of each pandemic action plan stands on the following pillars: • Surveillance of coronavirus-2 and COVID-19 infection: characterization of the virus, infection modes, diagnosing and detecting infection, contact tracing, annotation of data from confirmed cases, predicting mass infection outbreak, keeping a count, and estimation of mortality. R 0 of COVID-19 infection is estimated as 2-3.5 in the early phase, as even the asymptomatic patients or with mild pneumonia extruded large amounts of virus .
    keywords: cases; china; contact; coronavirus; covid-19; disease; healthcare; human; hygiene; infection; novel; outbreak; pandemic; public; transmission
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        item: #44 of 7819
          id: cord-024317-w1ep0wq8
      author: Ku, Zhiqiang
       title: Antibody therapies for the treatment of COVID-19
        date: 2020-04-30
       words: 2223
      flesch: 34
     summary: The New England journal of medicine 2016 Use of convalescent plasma therapy in SARS patients in Hong Kong. Figure angiotensin-converting enzyme 2; Fc: crystallizable fragment; ADE: antibody-dependent enhancement; PK: Pharmacokinetics; PD: pharmacodynamics; IL-6: Interleukine 6. SARS and MERS: recent insights into emerging coronaviruses The proximal origin of SARS-CoV-2 Origin and evolution of pathogenic coronaviruses The spike protein of SARS-CoV--a target for vaccine and therapeutic development Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC Structure, Function, and Evolution of Coronavirus Spike Proteins.
    keywords: antibodies; coronavirus; covid-19; infection; protein; sars; spike
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        item: #45 of 7819
          id: cord-024323-9w055rnn
      author: Blanco-Colino, Ruth
       title: Suspected Acute Abdomen as an Extrapulmonary Manifestation of COVID-19 Infection()
        date: 2020-05-04
       words: 979
      flesch: 49
     summary: This case report shows the current importance of reviewing the possible existence of respiratory symptoms during the anamnesis of patients initially referred for surgical evaluation. The presentation of gastrointestinal symptoms can vary according to the population, presenting as mild symptoms and prior to respiratory symptoms in some cases.
    keywords: covid-19; patients; symptoms
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        item: #46 of 7819
          id: cord-024348-nw3a0qco
      author: Béland, Daniel
       title: A Critical Juncture in Fiscal Federalism? Canada's Response to COVID-19
        date: 2020-04-20
       words: 2030
      flesch: 39
     summary: Federal transfers to provincial governments are central to fiscal federalism in Canada. As federal fiscal capacity and sustainability vastly exceed those of the provinces, even more dramatic re-evaluations of fiscal arrangements are possible.
    keywords: canada; covid-19; crisis; federal; federalism
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        item: #47 of 7819
          id: cord-024349-f8hm9v9g
      author: MICKLITZ, Hans-W.
       title: The COVID-19 Threat: An Opportunity to Rethink the European Economic Constitution and European Private Law
        date: 2020-04-23
       words: 2444
      flesch: 45
     summary: The COVID-19 threat has opened a window of opportunity for transgressing boundaries, for thinking the unthinkable: a fundamental revision of the European Economic Constitution and therewith European private law. What is urgently needed is a serious stocktaking of the state of affairs in terms of European private law in the light of the 17 Sustainable Development Goals that highlight the dark side of one-sided rules that protect employees and consumers without taking their counterproductive effects on the environment into account.
    keywords: constitution; covid-19; economy; european; law; society
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        item: #48 of 7819
          id: cord-024378-po1bu4v3
      author: CHAKRABORTY, Sweta
       title: How Risk Perceptions, Not Evidence, Have Driven Harmful Policies on COVID-19
        date: 2020-04-20
       words: 1445
      flesch: 44
     summary: key: cord-024378-po1bu4v3 authors: CHAKRABORTY, Sweta title: How Risk Perceptions, Not Evidence, Have Driven Harmful Policies on COVID-19 date: 2020-04-20 journal: nan DOI: 10.1017/err.2020.37 sha: doc_id: 24378 cord_uid: po1bu4v3 COVID-19 hits all of the cognitive triggers for how the lay public misjudges risk. Robust findings from the field of risk perception have identified unique characteristics of a risk that allow for greater attribution of frequency and probability than is likely to be aligned with the base-rate statistics of the risk.
    keywords: disease; media; public; risk
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        item: #49 of 7819
          id: cord-024564-ff5ex004
      author: Ricoca Peixoto, Vasco
       title: Epidemic Surveillance of Covid-19: Considering Uncertainty and Under-Ascertainment
        date: 2020-04-09
       words: 2795
      flesch: 40
     summary: In Europe in late February there was a fast rise in the number of confirmed cases in Italy, and the probability of importation of cases of COVID-19 may have been high in Europe until Italy stopped movement from Northern Italy and later from the rest of the country. A novel coronavirus emerging in China: key questions for impact assessment Quantifying bias of COVID-19 prevalence and severity estimates in Wuhan, China that depend on reported cases in international travelers WHO Collaborating Centre for Infectious Disease Modelling; MRC Centre for Global Infectious Disease Analysis Abdul Latif Jameel Institute for Disease and Emergency Analytics Relative sensitivity of international surveillance Estimation of COVID-19 outbreak size in Italy based on international case exportations Siettos C. Data-based analysis, modelling and forecasting of the novel coronavirus Preliminary estimation of the novel coronavirus disease [COVID-19] cases in Iran: a modelling analysis based on overseas cases and air travel data.
    keywords: ascertainment; cases; covid-19; health; measures; surveillance; transmission
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        item: #50 of 7819
          id: cord-024613-yump76qu
      author: Wu, Chunxing
       title: Recommendations for control and prevention of infections for pediatric orthopedics during the epidemic period of COVID-19
        date: 2020-04-23
       words: 3820
      flesch: 39
     summary: Pediatric orthopedic patients and accompanying personnel. Suspected patient: with a history of epidemiology and/or related symptoms, the patient should be transferred to the fever clinic in the isolation building for screening and diagnosis.
    keywords: control; coronavirus; covid-19; infection; patient; prevention; protection; sars
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        item: #51 of 7819
          id: cord-024614-6bu3zo01
      author: Tang, Daxing
       title: Prevention and control strategies for emergency, limited-term, and elective operations in pediatric surgery during the epidemic period of COVID-19
        date: 2020-03-26
       words: 5846
      flesch: 38
     summary: Pneumonia diagnosis and treatment plan for new coronavirus infection (trial version 5 revision) (in Chinese Announcement of National Health Commission of the People's Republic of China Perioperative prevention and control strategies for surgical patients in the context of new coronavirus pneumonia (in Chinese) Consensus on emergency surgery and infection prevention and control for severe trauma patients with 2019 novel coronavirus pneumonia For pediatric patients that cry more often and do not cooperate, appropriate sedation can be applied before surgery to reduce the risk of transmission of saliva and droplet.
    keywords: children; control; coronavirus; covid-19; epidemic; infection; medical; operation; patients; prevention; protection; surgery
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        item: #52 of 7819
          id: cord-024620-44bm91u1
      author: Bernal-Sprekelsen, Manuel
       title: Documento de consenso de la Sociedad Española de Medicina Intensiva, Crítica, y Unidades Coronarias (SEMICYUC), la Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello (SEORL-CCC) y la Sociedad Española de Anestesiología y Reanimación (SEDAR) sobre la traqueotomía en pacientes con COVID-19(♦)()
        date: 2020-05-11
       words: 3694
      flesch: 38
     summary: Tabla 1 Indicaciones de traqueotomía en la unidad de cuidados intensivos 10 • Prevención del daño laríngeo y de la vía aérea alta por intubación en pacientes sometidos a ventilación mecánica prolongada • [2] Recomendaciones acerca del cuidado de la traqueotomía La asistencia de los pacientes con COVID-19 traqueotomizados puede incrementar la exposición al contagio de los profesionales sanitarios y la diseminación de la infección.
    keywords: como; con; covid-19; cánula; debe; del; intubación; las; los; mecánica; pacientes; para; patients; por; procedimiento; puede; recomendaciones; riesgo; sobre; tracheotomy; traqueotomía; una; uso; ventilación
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        item: #53 of 7819
          id: cord-024634-ciuynofm
      author: DOBBS, Mary
       title: National Governance of Public Health Responses in a Pandemic?
        date: 2020-04-21
       words: 3827
      flesch: 46
     summary: It is necessary to identify them and consider how significant they are to the various levels or constituents, to what extent homogeneity or heterogeneity exists (eg regarding objectives, balance with other interests and broad approaches) and the capacity of other levels to accommodate the heterogeneity. Consequently, nation states have chosen different approaches.
    keywords: approach; covid-19; disease; health; immunity; potential; public
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        item: #54 of 7819
          id: cord-024649-y7nqz6vk
      author: Bösel, J.
       title: Neurologische Auswirkungen von COVID-19
        date: 2020-05-11
       words: 3040
      flesch: 34
     summary: Die Vorstellungen von Die Inaktivierung von ACE2 durch Virusbindung könnte so möglicherweise diesen Prozessen Vorschub leisten.
    keywords: ace2; als; auch; auf; aus; bei; bzw; covid-19; das; den; der; des; die; durch; eine; für; ist; mit; neurologischen; nicht; oder; patienten; patients; sars; sich; sind; und; von; werden; wie
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        item: #55 of 7819
          id: cord-024782-ffl4qtmb
      author: Schmitt, Willian
       title: Covid-19: round and oval areas of ground-glass opacity
        date: 2020-05-14
       words: 223
      flesch: 48
     summary: The Lancet Chest Imaging Appearance of COVID-19 Infection CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV) Currently, realtime reverse-transcription polymerase chain reaction is the reference standard test for the definitive diagnosis of COVID-19 infection.
    keywords: covid-19
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        item: #56 of 7819
          id: cord-024786-f33eb1nf
      author: van Rensburg, V
       title: Current evidence for directed and supportive investigational therapies against COVID-19
        date: 2020-04-24
       words: 4419
      flesch: 41
     summary: Nevertheless, owing to the possibility of potential harm by corticosteroids in viral infections, the WHO recommends against the routine use of corticosteroids in COVID-19 patients, unless used with caution for other indications where there are supportive data, such as sepsis and acute exacerbations of asthma and chronic obstructive pulmonary disease, or as part of clinical trials. A retrospective cohort study Clinical features and treatment of COVID-19 patients in northeast Chongqing Potential interventions for novel coronavirus in China: A systematic review A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 A randomized, controlled trial of Ebola virus disease therapeutics Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys Compassionate use of remdesivir for patients with severe Covid-19 Influenza virus polymerase inhibitors in clinical development Pharmacokinetics and concerns about clinical trials for 2019-nCoV infection Superheroes in autoimmune warfare: Biologic therapies in current SA practice The cytokine release syndrome (CRS) of severe COVID-19 and interleukin-6 receptor (IL-6R) antagonist tocilizumab may be the key to reduce the mortality Severe acute respiratory syndrome and the innate immune responses: Modulation of effector cell function without productive infection Bioinformatics analysis on molecular mechanism of ribavirin and interferon-α in treating MERS-CoV COVID-19: Consider cytokine storm syndromes and immunosuppression Anti-IL6R role in treatment of COVID-19-related ARDS Tocilizumab treatment in COVID-19: A single-center experience First case of COVID-19 in a patient with multiple myeloma successfully treated with tocilizumab Tocilizumab, an anti-IL6 receptor antibody, to treat Covid-19-related respiratory failure: A case report Rapid and severe Covid-19 pneumonia with severe acute chest syndrome in a sickle-cell patient successfully treated with tocilizumab Off-label use of tocilizumab in patients with SARS-CoV-2 infection Systematic review of treatment effects Corticosteroids as adjunctive therapy in the treatment of influenza The influence of corticosteroid treatment on the outcome of influenza A(H1N1pdm09)-related critical illness Early administration of oral oseltamivir increases the benefits of influenza treatment Temperature-sensitive mutants of influenza virus.
    keywords: covid-19; disease; hcq; patients; study; treatment; trials; use
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        item: #57 of 7819
          id: cord-024935-22jvb4i7
      author: Kundu, Shinjini
       title: How Might AI and Chest Imaging Help Unravel COVID-19’s Mysteries?
        date: 2020-05-06
       words: 3327
      flesch: 42
     summary: [34] , with respiratory failure the leading cause of mortality among COVID-19 pneumonia patients in Wuhan [35] . Mortality among COVID-19 patients rises with increased burden on healthcare resources available in the community [1] , which can raise the stakes on an already strained healthcare system.
    keywords: chest; covid-19; imaging; learning; lung; patients; pneumonia
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        item: #58 of 7819
          id: cord-024936-ncia0h9m
      author: Luker, Gary D.
       title: Transitioning to a New Normal after COVID-19: Preparing to Get Back on Track for Cancer Imaging
        date: 2020-04-15
       words: 2950
      flesch: 46
     summary: As the outbreak of COVID-19 emerged in the United States, there were two main priorities that clinics had with regard to decision-making on cancer imaging appointments: keeping people healthy and preserving personal protective equipment resources. How will institutions manage a surge in cancer imaging patients after the shutdown ends?'
    keywords: appointments; cancer; covid-19; imaging; institutions; patients; research
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        item: #59 of 7819
          id: cord-024956-oht0v33s
      author: Yu, Minhua
       title: Thin-section Chest CT Imaging of Coronavirus Disease 2019 Pneumonia: Comparison Between Patients with Mild and Severe Disease
        date: 2020-04-23
       words: 2502
      flesch: 43
     summary: Patients with severe form of the disease had more extensive opacification of the lung parenchyma than did patients with mild disease. Patients with mild form of disease showed pure GGO more often than patients with severe disease, while the latter was more frequently associated with pure consolidations.
    keywords: covid-19; disease; form; patients; pneumonia
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        item: #60 of 7819
          id: cord-024991-9ybyt89r
      author: Hastings, Gerard
       title: COVID-19: our last teachable moment
        date: 2020-05-21
       words: 4261
      flesch: 59
     summary: This dominance is coupled with inherent irresponsibility, as we in public health again know all too well. Public health has never been in higher regard: appreciation of health workers and the need for greater investment in the health sector are at a premium.
    keywords: business; capitalism; change; covid-19; data; health; need; people; world
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        item: #61 of 7819
          id: cord-025176-f0frlpwh
      author: Coimbra, Raul
       title: Resuming elective surgical services in times of COVID-19 infection
        date: 2020-05-19
       words: 2888
      flesch: 36
     summary: COVID-19: recommendations for management of elective surgical procedures Re-opening facilities to provide nonemergent non-COVID-19 healthcare: phase I Recovery of surgical services during and after COVID-19 American Association of Orthopaedic Surgeons Guidance for resuming GI endoscopy and practice operations after the COVID-19 pandemic National Coronavirus Response: a road map to reopening Association of periOperative Registered Nurses and the American Hospital Association Recommendation to optimize safety of elective surgical care while limiting the spread of COVID-19: primum non nocere Joint statement on re-introduction of hospital and office-based procedures in the COVID-19 climate for the practicing urogynecologist and gynecologist. Therefore, when considering resuming elective surgical care, the first step is to understand the COVID-19 infection prevalence and incidence in the community and the current impact in a hospital.
    keywords: care; covid-19; hospital; patients; stage; surgery; time
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        item: #62 of 7819
          id: cord-025482-9iy4fxd5
      author: Zhong, Yueyang
       title: COVID-19: Evidence of the Eye
        date: 2020-05-28
       words: 536
      flesch: 47
     summary: First, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause ocular manifestations. Ocular manifestations may present as the initial and the only symptoms of infection.
    keywords: covid-19; patients
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        item: #63 of 7819
          id: cord-025556-oyfx3ij5
      author: THUNSTRÖM, LINDA
       title: Testing for COVID-19: willful ignorance or selfless behavior?
        date: 2020-05-08
       words: 6779
      flesch: 53
     summary: We therefore conclude that the positive effect of being an extrovert on willingness to test for COVID-19 is likely due to social health benefits weighing more heavily in their decision than their private costs from potential self-isolation for 14 days, should the test come back positive. Surprisingly, the people most likely to widely spread COVID-19 – the extraverts, others who meet more people in their daily lives and younger people – are the most willing to take a test.
    keywords: covid-19; days; health; participants; people; self; test; testing; variable
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        item: #64 of 7819
          id: cord-025557-hxn46xnn
      author: Rayment, Erica
       title: Pandemic Parliaments: Canadian Legislatures in a Time of Crisis
        date: 2020-05-15
       words: 2116
      flesch: 35
     summary: Following the declaration of an emergency, the number of sitting days in most legislatures has been limited. The purpose of this research note is twofold: (1) to document how Canadian legislatures have changed in response to the COVID-19 pandemic and (2) to assess the effect of these responses on legislatures’ ability to fulfill their core functions.
    keywords: emergency; legislation; legislatures; pandemic
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        item: #65 of 7819
          id: cord-025608-pj5qg98a
      author: Santillán-García, Azucena
       title: Living evidence in response to controversies about the use of antimalarials in COVID-19
        date: 2020-05-29
       words: 684
      flesch: 40
     summary: There is already a live repository of scientific evidence on the effectiveness of antimalarials against coronavirus infection that currently includes, among many other things, 20 systematic reviews, 4 clinical trials that report results and 115 registered ongoing randomized trials. It is therefore essential that clinicians have tools available that ensure good quality scientific evidence that is updated almost in real time.
    keywords: covid-19; evidence
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        item: #66 of 7819
          id: cord-025619-vtk2ujx9
      author: None
       title: Chloroquine and hydroxychloroquine increase risk of death in COVID-19
        date: 2020-05-30
       words: 244
      flesch: 51
     summary: key: cord-025619-vtk2ujx9 authors: nan title: Chloroquine and hydroxychloroquine increase risk of death in COVID-19 date: 2020-05-30 journal: Reactions Weekly DOI: 10.1007/s40278-020-79019-x sha: doc_id: 25619 cord_uid: vtk2ujx9 nan Two months ago, the WHO initiated the Solidarity Trial to evaluate the safety and efficacy of four drugs and drug combinations against COVID-19, said Dr Tedros Adhanom Ghebreyesus, Director-General of WHO, at a media briefing on COVID-19 on 25 May 2020.
    keywords: covid-19
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        item: #67 of 7819
          id: cord-025689-g3q5bo38
      author: Carvalho, Joana
       title: Challenges in the practice of Sexual Medicine, Sex Therapy, and Sexual Counseling in the time of COVID-19
        date: 2020-05-31
       words: 2396
      flesch: 31
     summary: The recent scenario of pandemic has exposed several vulnerabilities within worldwide healthcare and social systems, some of them including services concerning sexual health and human sexual rights. In addition, is worth mentioning the effects of pandemic in the working routines of sexual health professionals.
    keywords: covid-19; health; professionals; relationship; sexuality; women
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        item: #68 of 7819
          id: cord-025747-iuzoio29
      author: Murphy, Rebecca
       title: Challenges and opportunities for enhanced cognitive behaviour therapy (CBT-E) in light of COVID-19
        date: 2020-05-04
       words: 8910
      flesch: 49
     summary: In adolescent patients who follow extreme dietary rules that exclude several food groups, or who have lost weight in the last 4 weeks, therapists should provide nutritional education and advice based on National Food and Nutrition Guidelines, adapted for adolescent underweight eating disorder patients, with specific suggestions for meals and snacks using food exchange lists (Dalle Grave and Calugi, 2020). Second, we discuss new problems that patients with eating disorders may face in this period.
    keywords: cbt; covid-19; disorders; eating; face; fairburn; patients; therapist; treatment
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        item: #69 of 7819
          id: cord-025765-gd8217va
      author: Weersink, Alfons
       title: Economic thoughts on the potential implications of COVID‐19 on the Canadian dairy and poultry sectors
        date: 2020-05-06
       words: 3789
      flesch: 55
     summary: It is expected that fluid milk sales will continue at this rate as the higher milk consumption by individuals at home offsets a decline in food service demand (i.e., school lunch programs). Wing consumption primarily occurs outside the home, and the sharp drop in wholesale wing prices corresponds to the reduction in food service demand.
    keywords: covid-19; dairy; demand; food; grocery; milk; poultry; stores; supply
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        item: #70 of 7819
          id: cord-025768-tz5jajeb
      author: Deaton, B. James
       title: Food security and Canada's agricultural system challenged by COVID‐19
        date: 2020-04-26
       words: 3849
      flesch: 46
     summary: From the perspective of food insecurity as measured by the Canadian Community Health Survey, COVID-19 is a unique income shock that is expected to increase the prevalence of household food insecurity. The Globe and Mail A hundred years on, will there be another Great Depression?The Guardian Assessing the effect of food retail subsidies on the price of food in remote Indigenous communities: A case study of nutrition North Canada Section 1: Food in Canada Canadian community health survey-annual component (CCHS)-2020 Determining food security status Household food insecurity in Canada Geographic and socio-demographic predictors of household food insecurity in Canada The relationship between food banks and food security: Insights from Canada.
    keywords: canada; canadian; covid-19; food; health; household; income; insecurity
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        item: #71 of 7819
          id: cord-025886-259357pg
      author: Mehrotra, Sanjay
       title: A model of supply‐chain decisions for resource sharing with an application to ventilator allocation to combat COVID‐19
        date: 2020-05-02
       words: 6807
      flesch: 50
     summary: The problem of estimating mechanical ventilator demand in the United States during an influenza pandemic was considered in Meltzer, Patel, Ajao, Nystrom, and Koonin (2015) . In the context of ventilator allocation, a conceptual framework for allocating ventilators in a public emergency is proposed in Zaza et al. (2016) .
    keywords: allocation; covid-19; demand; inventory; model; patients; states; time; ventilators
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        item: #72 of 7819
          id: cord-025971-09u3kn1k
      author: Mills, William R.
       title: An Outbreak Preparedness and Mitigation Approach in Home Health and Personal Home Care During the COVID-19 Pandemic
        date: 2020-06-02
       words: 2234
      flesch: 39
     summary: To address the threat posed by COVID-19, we developed a comprehensive outbreak preparedness and mitigation strategy, with a primary objective of protecting home health and personal home care patients. In addition, we report a COVID-19 positive case series of home health and personal home care patients, summarizing our initial experience in supporting patients during the pandemic.
    keywords: care; covid-19; health; home; infection; patients
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        item: #73 of 7819
          id: cord-026130-ki7bn67o
      author: Sharma, Anand Kumar
       title: Novel Coronavirus Disease (COVID-19)
        date: 2020-06-05
       words: 5082
      flesch: 56
     summary: The release of new viruses from the host cell is the final step of the virus infection cycle. The Coronaviridae Study Group (CSG) of the International Committee on Taxonomy of Viruses (ICTV), which is responsible for the classification and nomenclature of the family Coronaviridae, has assessed this virus as bat Severe Acute Respiratory Syndrome Corona Viruses (SARS-CoVs) and designated it as SARS-CoV-2 [1-3].
    keywords: coronavirus; cov-2; covid-19; disease; people; sars; spread; symptoms; virus; viruses
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        item: #74 of 7819
          id: cord-026334-n8ek9fw3
      author: Shah, Pooja
       title: Prevention is Better than Cure: An Application of Big Data and Geospatial Technology in Mitigating Pandemic
        date: 2020-06-06
       words: 2674
      flesch: 47
     summary: Cities like Mumbai, Ahmedabad, Pune, Delhi, etc. which are highly vulnerable to COVID-19 should map COVID-19 related information for better visualization. This app records details like location, demographic details, travel history and contact with COVID-19 positive patient.
    keywords: city; covid-19; data; gis; information; land; pandemic; technology
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        item: #75 of 7819
          id: cord-026336-xdymj4dk
      author: Ranjan, Rajesh
       title: Temporal Dynamics of COVID-19 Outbreak and Future Projections: A Data-Driven Approach
        date: 2020-06-06
       words: 3690
      flesch: 51
     summary: For India and Russia, the growths are still close to exponential, and therefore there is a significant disparity in predictions by different epidemiological models. key: cord-026336-xdymj4dk authors: Ranjan, Rajesh title: Temporal Dynamics of COVID-19 Outbreak and Future Projections: A Data-Driven Approach date: 2020-06-06 journal: Trans Indian Natl DOI: 10.1007/s41403-020-00112-y sha: doc_id: 26336 cord_uid: xdymj4dk Long-term predictions for an ongoing epidemic are typically performed using epidemiological models that predict the timing of the peak in infections followed by its decay using non-linear fits from the available data.
    keywords: countries; covid-19; data; epidemic; epidemiological; models
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        item: #76 of 7819
          id: cord-026340-2nf97zvc
      author: Singh, Ranjana
       title: Chloroquine: A Potential Drug in the COVID-19 Scenario
        date: 2020-06-07
       words: 7557
      flesch: 47
     summary: Does CQ have anti-viral effects? This botanical has reported that anti-viral effect may aid to reduce the dose of CQ for prophylactic or therapeutic regimen.
    keywords: acid; activity; cell; chloroquine; coronavirus; cov2; covid-19; et al; hcq; host; infection; protein; sars; virus; viruses
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        item: #77 of 7819
          id: cord-026371-5jrvkk60
      author: Craighead, Christopher W.
       title: Pandemics and Supply Chain Management Research: Toward a Theoretical Toolbox
        date: 2020-05-20
       words: 10077
      flesch: 37
     summary: Decision Sciences Institutionalized organizations: Formal structure as myth and ceremony Event system theory: An event-oriented approach to the organizational sciences WWE Q1 earnings call Determinants of corporate borrowing How global media covers the coronavirus Responses to supplier-induced disruptions: A fuzzy-set analysis Imitation of management practices in supply networks: Relational and environmental effects Designer and supply chain digital revolution: How COVID-19 is changing the fashion industry General Motors will help manufacture hospital ventilators to fight coronavirus Game theory From mass production to mass customization: Hindrance factors, structural inertia, and transition hazard Flow coordination and information sharing in supply chains: Review, implications, and directions for future research Decision bias in the newsvendor problem with a known demand distribution: Experimental evidence Designer brand Louis Vuitton starts making masks, hospital gowns for coronavirus outbreak Apple, Google give a look at coronavirus tracking tech, promise more privacy protections Portfolio spillover of institutional investor activism: An awareness-motivation-capability perspective False Alarm: The Truth About the Epidemic of Fear Not all threats are created equal: How implicitness and timing affect the effectiveness of threats in negotiations Managing firm resources in dynamic environments to create value: As such, RDT is a natural fit with supply chain research (e.g., Jean, Kim, & Sinkovics, 2012; Touboulic, Chicksand, & Walker, 2014) , that could transcend into the pandemic context (see Table 1 ).
    keywords: chain; copyright; covid-19; demand; effects; event; example; firms; managers; options; pandemic; research; resource; scholars; supply; supply chain; theory; transiliency
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        item: #78 of 7819
          id: cord-026603-h4zy3244
      author: Gallo, Oreste
       title: “Is really the cancer population at risk for more severe COVID-19? Some hints from the cytokine profile”
        date: 2020-06-10
       words: 962
      flesch: 32
     summary: Our analysis was also the first, to the best of our knowledge, to directly compared COVID-19 cancer and non-cancer patients from both a clinical and immunological point of view. Dear Editor, we read with great interest the meta-analysis by Afshar and colleagues regarding the very high case-fatality rate in cancer patients infected with SARS-CoV-2.
    keywords: cancer; covid-19; patients
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        item: #79 of 7819
          id: cord-026764-eag13h3p
      author: Sumner, O.
       title: Age-appropriate antibiotics
        date: 2020-06-12
       words: 834
      flesch: 46
     summary: The Faculty of General Dental Practice (FGDP) produced a comprehensive list of guidance, news and resources for general dental practice in the COVID-19 era. The latest Cochrane commentary on personal protective equipment (PPE) for general dental practice states 'none of the 24 identified studies... was based in the dental environment or included members of the dental team' .
    keywords: dental; hydroxychloroquine; patients
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        item: #80 of 7819
          id: cord-026788-4d3r9rj8
      author: Singla, Vikas
       title: Hepatobiliary and Pancreatic Manifestations of Coronavirus Disease 2019
        date: 2020-05-16
       words: 1956
      flesch: 45
     summary: The prevalence and severity of COVID-19 patients with the aforementioned diseases may be different. 23 Gamma glutamyl transferase (GGT) and alkaline phosphatase may be elevated in COVID-19 patients.
    keywords: covid-19; disease; liver; patients; sars
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        item: #81 of 7819
          id: cord-026792-jsqa4pmu
      author: Samanta, Jayanta
       title: 2019 Novel Coronavirus Infection: Gastrointestinal Manifestations
        date: 2020-05-16
       words: 3797
      flesch: 43
     summary: Data are not adequate yet to prove or disprove the theory of whether IBD patients are at an increased risk of infection in this COVID-19 era. The risk of SARS-CoV-2 in immunosuppressed IBD patients.
    keywords: coronavirus; covid-19; disease; ibd; infection; novel; patients; sars; symptoms
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        item: #82 of 7819
          id: cord-026803-p1o4qc1h
      author: Maddury, Jyotsna
       title: Need of the Hour— COVID-19 for Cardiologists
        date: 2020-04-16
       words: 1673
      flesch: 38
     summary: The main aim of this article is to summarize the available evidence of cardiac involvement in COVID-19 patients and outlay precautions to patients with underlying cardiovascular disease (CVD). Initial studies showed low association of chronic cardiac diseases (10%) in COVID-19 patients along with the acute cardiac injury accounting to 23%.
    keywords: covid-19; disease; heart; patients; sars
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        item: #83 of 7819
          id: cord-026806-pn4lwhr7
      author: Zargar, Showkat Ali
       title: Gastrointestinal Endoscopy during COVID: Do Some, Leave Most
        date: 2020-05-16
       words: 1500
      flesch: 43
     summary: We have to learn to live with such outbreaks of infectious disease. We live in global village and likely to face challenges of emergence and re-emergence of infectious disease in future because of environmental pollution, movement of refugees and immigrants, international travel, changing lifestyle, and behavior of the population.
    keywords: control; covid-19; disease; sars
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        item: #84 of 7819
          id: cord-026811-6bdzut3d
      author: Jha, Ashish K.
       title: Emerging Treatment and Prevention Strategies against COVID-19: A Brief Update
        date: 2020-05-16
       words: 2690
      flesch: 40
     summary: The FDA has issued guidance for use of COVID-19 convalescent plasma in patients with serious COVID-19. Limited evidence shows that COVID-19 convalescent plasma can be used as a treatment of COVID-19 without the occurrence of severe adverse events.
    keywords: convalescent; covid-19; hcq; patients; plasma; treatment; use
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        item: #85 of 7819
          id: cord-026991-75sbxnsc
      author: Sultan, Omar Muayad
       title: Pulmonary ct manifestations of COVID-19: changes within 2 weeks duration from presentation
        date: 2020-06-17
       words: 2902
      flesch: 50
     summary: Therefore, CT scan is done at different times in different institutions worldwide necessitating that specific consideration to be taken for such observed difference in the appearance of CT pulmonary findings according to the time of the scans. There is evidence of the prognostic value of chest CT which has been shown by recent studies, where a specific score by CT scan could predict the mortality of patients with COVID-19
    keywords: changes; covid-19; group; patients; study
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        item: #86 of 7819
          id: cord-027027-2vxnmiyj
      author: Schartau, Patricia
       title: Male mortality and the German response: lessons from COVID‐19
        date: 2020-06-04
       words: 2042
      flesch: 50
     summary: As mentioned, in Germany the diagnostics infrastructure was readily in place and scaled up upon the emergence of COVID-19 cases. 2 UK data collected and analysed from 1st February-25th April 2020 confirmed (amongst other factors) a male hazard ratio of 1.99 in COVID-19 related deaths when compared to females.
    keywords: countries; covid-19; germany; health; men; mortality
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        item: #87 of 7819
          id: cord-027031-3olk1i7v
      author: Hillson, Rowan
       title: COVID‐19: diabetes and death. A call to action
        date: 2020-06-09
       words: 1604
      flesch: 70
     summary: The pandemic continues but the catastrophic effect of COVID-19 on people with diabetes means that diabetes care, where paused, must be resumed as quickly as possible, as safely as possible. • Everyone with diabetes must have access to diabetes care.
    keywords: diabetes; people; type
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        item: #88 of 7819
          id: cord-027036-lvcxrmih
      author: Shaw, Ken
       title: The impact of diabetes on COVID‐19 infection
        date: 2020-06-09
       words: 2057
      flesch: 32
     summary: 2 Such disturbances of immune function are very likely to have significant impact on the outcome of COVID-19 infection complicated by diabetes. These early reports of COVID-19 infection included observations of 52 critically ill adult patients with coronavirus pneumonia admitted to the ICU at the Wuhan Jin Yin-tan hospital, where diabetes was found in twice the number of individuals who died compared to those who survived (22% vs 10%).
    keywords: coronavirus; covid-19; diabetes; infection; pandemic; patients
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        item: #89 of 7819
          id: cord-027057-g7onopr1
      author: George, Marcus L.
       title: Effective Teaching and Examination Strategies for Undergraduate Learning During COVID-19 School Restrictions
        date: 2020-06-17
       words: 7418
      flesch: 44
     summary: Mocks exams utilized in this study served to both promote student learning of the topics being examined as well as get students acclimatized with the attempting of exams on the online platform. • Students must have NO opportunity to return to previously attempted questions, hence minimizing possibility of collusion by students.
    keywords: course; covid-19; exam; learning; lecturer; methodology; questions; quiz; students; teaching
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        item: #90 of 7819
          id: cord-027231-k49e9vy6
      author: Inchingolo, Riccardo
       title: Lung ultrasound as an extension of medical examination for COVID-19 pneumonia: much more than an imaging technique
        date: 2020-06-19
       words: 472
      flesch: 33
     summary: key: cord-027231-k49e9vy6 authors: Inchingolo, Riccardo; Smargiassi, Andrea; Soldati, Gino; Demi, Libertario title: Lung ultrasound as an extension of medical examination for COVID-19 pneumonia: much more than an imaging technique date: 2020-06-19 journal: Am J Obstet Gynecol DOI: 10.1016/j.ajog.2020.06.034 sha: doc_id: 27231 cord_uid: k49e9vy6 nan On April 2020, we reported our experience performing lung ultrasound (LUS) on the first pregnant woman admitted for COVID-19 pneumonia 1 The Diagnosis of Pneumonia in a Pregnant Woman with COVID-19 Using Maternal Lung Ultrasound Diagnosis of COVID-19 pneumonia in pregnant women: 1 can we rely on lung ultrasound?
    keywords: lung; pneumonia
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        item: #91 of 7819
          id: cord-027543-fp1pib0y
      author: Link, Hartmut
       title: Müssen wir die Supportivtherapie bei Krebspatienten anpassen?
        date: 2020-06-30
       words: 702
      flesch: 37
     summary: Risikokonstellationen [11] : -Patienten unter aktueller Chemotherapie oder jene, die in den letzten 3 Monaten immer wieder eine Chemotherapie erhalten haben -Patienten, die eine umfassende Strahlentherapie erhalten -Personen, die in den letzten 6 perten, die diese aufgrund ihrer Fachkenntnisse basierend auf Analogieschlüssen formulieren. Die Indikation sollte nach den bestehenden Leitlinien gestellt werden
    keywords: bei; covid-19; der; die; eine; mit; und
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        item: #92 of 7819
          id: cord-027578-yapmcvps
      author: Menzies, Rachel E.
       title: Death anxiety in the time of COVID-19: theoretical explanations and clinical implications
        date: 2020-06-11
       words: 5563
      flesch: 36
     summary: Given this, what role might death anxiety be playing in the current pandemic? Death anxiety and the COVID-19 pandemic With the exception of a handful of studies, the majority of TMT research has been conducted under laboratory conditions; i.e. for those in the mortality salience condition, death is usually primed in the form of two short questions about one's death, which participants are asked to respond to. key: cord-027578-yapmcvps authors: Menzies, Rachel E.; Menzies, Ross G. title: Death anxiety in the time of COVID-19: theoretical explanations and clinical implications date: 2020-06-11 journal:
    keywords: anxiety; covid-19; death; death anxiety; et al; fear; health; menzies; mortality; salience; terror
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        item: #93 of 7819
          id: cord-027589-v03xnlx9
      author: Carrillo-Larco, Rodrigo M.
       title: Using country-level variables to classify countries according to the number of confirmed COVID-19 cases: An unsupervised machine learning approach
        date: 2020-06-15
       words: 7083
      flesch: 55
     summary: With country-level pre-COVID-19-pandemic variables, we aimed to cluster countries in groups with shared profiles of the COVID-19 pandemic. Global and regional organizations could use country clusters to organize similar aid to countries in the same cluster, while prioritizing clusters likely to experience the worse outcomes.
    keywords: analysis; cases; clusters; countries; covid-19; data; number; variables
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        item: #94 of 7819
          id: cord-027759-5mz0qlwq
      author: Zhou, Anli Yue
       title: Mental health and the medical profession during the COVID-19 pandemic
        date: 2020-06-01
       words: 720
      flesch: 32
     summary: Managing mental health challenges faced by healthcare workers during covid-19 pandemic Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed Association between physician burnout and patient safety, professionalism, and patient satisfaction: a systematic review and meta-analysis Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019 key: cord-027759-5mz0qlwq authors: Zhou, Anli Yue; Panagioti, Maria title: Mental health and the medical profession during the COVID-19 pandemic date: 2020-06-01 journal: Occup Med (Lond) DOI: 10.1093/occmed/kqaa076 sha: doc_id: 27759 cord_uid: 5mz0qlwq nan The coronavirus disease (COVID-19) pandemic threatens to overwhelm well-established healthcare systems, and medical professionals have to work under extreme pressures and uncertainty
    keywords: covid-19; health
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        item: #95 of 7819
          id: cord-027798-aq13cugo
      author: Kenny, Sue
       title: Covid-19 and community development
        date: 2020-06-01
       words: 1378
      flesch: 47
     summary: At the beginning of May, 2020, what can those committed to community development be doing in response to the Covid-19 pandemic and the changing socio-political milieu? Of course, like the suggestions above, those committed to community development cannot do this alone.
    keywords: community; covid-19; development; pandemic
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        item: #96 of 7819
          id: cord-027905-edb9yozz
      author: Narula, Rajneesh
       title: Policy opportunities and challenges from the COVID-19 pandemic for economies with large informal sectors
        date: 2020-06-25
       words: 5438
      flesch: 40
     summary: I focus on the urban component of informality, where both informal employment and informal enterprises are especially vulnerable to the pandemic-induced economic shock. Large firms (whether MNEs or domestic firms) sub-contract considerable activity to informal enterprises, but this is precarious in character.
    keywords: actors; countries; covid-19; crisis; economy; enterprises; firms; informality; pandemic; sector; workers
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        item: #97 of 7819
          id: cord-028034-pjotppso
      author: Kang, Jian‐Sheng
       title: Vitamin intervention for cytokine storm in the patients with coronavirus disease 2019
        date: 2020-06-19
       words: 1488
      flesch: 40
     summary: However, a recent preprint of medRxiv about Vd suppressing cytokine storm in COVID-19 patients was withdrawn by the authors because they noticed the idiosyncrasy of Vd across different countries. 1-3 Consequently, the dose ranges of Vc and Vd among 90-1000 mg and 400-1600 IU, respectively, might be enough and safe for the prevention or treatment of the cytokine storm caused by neutrophil, whereas for the cases not related to neutrophil, high dose of Vc or Vd might be also helpful for the treatment of COVID-19 patients due to the multifaceted roles of Vd and Vc. 9, 16, 18 As the global pandemic is still growing, if the vitamin intervention for cytokine storm could be proved to be applicable and efficient, it would be tremendously helpful and easy to protect the patients with COVID-19 worldwide from the cytokine storm-related death.
    keywords: covid-19; cytokine; storm
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        item: #98 of 7819
          id: cord-028163-ay37zzj5
      author: Hussain, Yaseen
       title: COVID-19 in five neighbouring limited resources countries: A financial and health threats
        date: 2020-06-30
       words: 693
      flesch: 57
     summary: In the near future, the total number of confirmed cases is expected to increase significantly in 16 limited resources or developing countries. It is 36 reported that up till now more than 1.5 billion people are suffered from the crisis, with an Recently, Iran is suffering from a very troublesome state of economic growth rate.
    keywords: countries; covid-19
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        item: #99 of 7819
          id: cord-028285-n4dommet
      author: Weilongorska, Natasha L.
       title: COVID-19: What are the challenges for NHS surgery?
        date: 2020-07-02
       words: 9766
      flesch: 42
     summary: The need to segregate suspected or confirmed COVID-19 patients into designated operating rooms has spurred the use of traffic light systems to denote case status. Literature from other countries recommending negative pressure ventilation in the management of COVID-19 cases, 78,79 initially generated concern.
    keywords: cases; covid-19; guidance; healthcare; nhs; operating; pandemic; patients; ppe; risk; rooms; screening; services; staff; surgeons; surgery; surgical; testing
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        item: #100 of 7819
          id: cord-028300-u8hogdyf
      author: Koop, Royce
       title: Has the COVID-19 Pandemic Affected MPs’ Representational Activities?
        date: 2020-06-09
       words: 1918
      flesch: 49
     summary: key: cord-028300-u8hogdyf authors: Koop, Royce; Blidook, Kelly; Fuga, Lesley Anne title: Has the COVID-19 Pandemic Affected MPs’ Representational Activities? date: 2020-06-09 journal: nan DOI: 10.1017/s0008423920000566 sha: doc_id: 28300 cord_uid: u8hogdyf The COVID-19 pandemic has necessarily affected the operation of Canada's Parliament and, thus, the activities of Members of Parliament (MPs) (Malloy, 2020; Rayment and VandenBeukel, 2020). The COVID-19 pandemic has necessarily affected the operation of Canada's Parliament and, thus, the activities of Members of Parliament (MPs) (Malloy, 2020; Rayment and VandenBeukel, 2020) .
    keywords: covid-19; mps; pandemic; service
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        item: #101 of 7819
          id: cord-028321-um448esn
      author: Pollock, Kim
       title: Embracing telemedicine into your otolaryngology practice amid the COVID-19 crisis: An invited commentary
        date: 2020-07-02
       words: 373
      flesch: 47
     summary: 2 Modifier CR should be appended to telephone call codes and any other codes for services provided that are not considered telehealth services such as e-visits and digital check-ins. Historically, CMS has not paid for telephone call codes 99441-99443.
    keywords: medicare; services
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        item: #102 of 7819
          id: cord-028444-bl9ahsxk
      author: Sarfo, Anthony Kwabena
       title: Application of Geospatial Technologies in the COVID-19 Fight of Ghana
        date: 2020-07-04
       words: 4604
      flesch: 48
     summary: Comparing population distribution and COVID-19 cases (Fig. 5) , there is seemingly a link in infection trends and the regional level of Ghana's population distribution.. 10 Future trends in COVID-19 cases on Ghana Sarabanga River region Distribution and trend analysis of COVID-19 in India: geospatial approach Coronavirus: Ghana govment COVID-19 tracker mobile app be solid tech intervention or needless app?-BBC News Pidgin Coronavirus:10 days of hospital building in 60 seconds-BBC News.
    keywords: accra; cases; covid-19; data; ghana; health; infection; population; regions; spread; trend; use
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        item: #103 of 7819
          id: cord-028525-0ckagrt1
      author: Yung, Chee Fu
       title: Household Transmission of SARS-CoV-2 from Adults to Children
        date: 2020-07-04
       words: 1707
      flesch: 50
     summary: The mean interval between last exposure and the single NP swab sample date of child cases (3.5 days) and non-cases (4 days) were not biased. Young children <5 years old were at lowest risk of infection (1.3%).
    keywords: attack; children; covid-19; household
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        item: #104 of 7819
          id: cord-028529-d1g33f1c
      author: Agrifoglio, Alexander
       title: COVID-19 and fungal co-infections: we must keep them in mind
        date: 2020-07-04
       words: 539
      flesch: 32
     summary: As well described in the manuscript, invasive fungal infections are beginning to be described in some series but unfortunately many remain undiagnosed and the actual impact on mortality, hospital stay and other complications is unknown. How the authors describe, there seems to be an association between COVID-19 and the presence of invasive pulmonary aspergillosis (IPA), which, of course, will require more research to support these preliminary results.
    keywords: covid-19; patients
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        item: #105 of 7819
          id: cord-028552-w4yluham
      author: Maurya, Deepak
       title: Development of Autonomous Advanced Disinfection Tunnel to Tackle External Surface Disinfection of COVID-19 Virus in Public Places
        date: 2020-07-04
       words: 2364
      flesch: 54
     summary: This paper describes a robust autonomous disinfection tunnel to disinfect external surfaces of COVID-19 virus such as clothes and open body sections in public places such as airports, office complexes, schools, and malls. The literature suggests that COVID-19 virus infection can be arrested effectively with 0.1% sodium hypochlorite solution within 1 min (Kampf 2020) .
    keywords: chamber; covid-19; disinfectant; disinfection; person; tunnel; virus
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        item: #106 of 7819
          id: cord-028557-68jypaaw
      author: Joshi, Jaiteerth R.
       title: COVSACK: an innovative portable isolated and safe COVID-19 sample collection kiosk with automatic disinfection
        date: 2020-07-05
       words: 3792
      flesch: 50
     summary: This technological innovation, to certain extent, has changed the way the testing of COVID-19 patients carried out in the country. Very recently in India, particularly in Kerala (Sruthi 2020) , telephone booth like chambers are employed for collection of samples from COVID-19 patients, where the healthcare worker is inside the booth, while the patients are outside.
    keywords: chamber; collection; covid-19; disinfectant; healthcare; kiosk; patients; sample; virus
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        item: #107 of 7819
          id: cord-028566-avl980hg
      author: Palko, Hannah Catherine
       title: In fighting common threats, people’s deep commitment to taking collective action matters: examples from China’s COVID-19 battle and her other combats
        date: 2020-07-06
       words: 4534
      flesch: 53
     summary: [1] The label became almost obsolete after the establishment of the People's Republic of China in 1949, with Chairman Mao Zedong's famous proclamation thatThe Chinese people have stood up (Lau 2008; Mao 1949) . In 2017, Chinese historians reached a consensus that the resistance began in as early as 1931 in Northeast China right after the September 18 Incident (also known as Manchurian Incident among historians outside China); and that the resistance lasted 14 years till September 2, 1945 when Japan's unconditional surrender was formally signed (Sun 2017) .
    keywords: china; chinese; coronavirus; covid-19; february; ibid; mission; people; team; war
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        item: #108 of 7819
          id: cord-028605-ehercdou
      author: Merchan, Cristian
       title: COVID-19 pandemic preparedness: A practical guide from an operational pharmacy perspective
        date: 2020-06-16
       words: 4370
      flesch: 28
     summary: At the time of a cardiopulmonary arrest, required medications were prepared by pharmacists outside the patient's room and passed to the resuscitation nurse through the door for immediate use. A number of dedicated refrigerators were resourced to enable storage of essential medications and extension of the beyond-use dates (BUDs) of batched infusion bags of opioids and sedatives.
    keywords: adc; care; compounding; covid-19; health; medication; number; pandemic; patients; pharmacy; staff; team; use
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        item: #109 of 7819
          id: cord-028624-dzx62k23
      author: Yong, Celina M.
       title: Picking Up the Torch: Our Mission as the New FIT & EC Section Editors
        date: 2020-07-14
       words: 194
      flesch: -4
     summary: The emergence of sports cardiology as a specialty Surgical training in an era of change and innovation: transition within a transition Call for FITs/ECs to become engaged with social media Preparing fellows for precision cardiology: are we ready? Finding mentorship among your peers: sharing the wealth Mentorship during fellowship Women in cardiology: fellows' perspective Breaking the catheterization laboratory ceiling Virtual learning during the COVID-19 pandemic: a disruptive technology in graduate medical education COVID-19: the isolation that has brought us together Adapting the educational environment for cardiovascular fellows-in-training during the COVID-19 pandemic We seek external Complex, higher-risk, and indicated PCI (CHIP) fellowship: putting training into practice Cardiac critical care: training pathways and transition to early career
    keywords: training
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        item: #110 of 7819
          id: cord-028972-1athnjkh
      author: Etemad, Hamid
       title: Managing uncertain consequences of a global crisis: SMEs encountering adversities, losses, and new opportunities
        date: 2020-07-10
       words: 9180
      flesch: 24
     summary: Such rapidly developing phenomena, seemingly beyond control initially, influenced the overall theme of this issue, although already accepted articles waiting to be placed in a regular publication were not written on the topic of crisis management. Given the gravity of the COVID-19 pandemic pushing many institutions into their crisis of survival, this issue adopted the overriding thematic topic of crisis management perspective to enable a richer discussion of different components of crisis management with a focus on SMEs and iSMEs based on the specific research of each of the articles accepted through the journal rigorous doubleblind review process.
    keywords: article; costs; crisis; enterprises; information; institutions; knowledge; management; need; smes; state; time; uncertainties; uncertainty
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        item: #111 of 7819
          id: cord-029106-gkck1u4y
      author: Ma, Lina
       title: COVID-19 Prevention: Use of Self-Reported Tools to Screen Frail Older Adults
        date: 2020-07-13
       words: 241
      flesch: 46
     summary: Rapid Guideline: Critical Care in Adults Clinical characteristics of coronavirus disease 2019 in China Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease Frailty in elderly people A simple frailty questionnaire (FRAIL) predicts outcomes in middle aged African Americans Novel frailty screening questionnaire (FSQ) predicts 8-year mortality in older adults in China Statements of role, if any, of medical writer or editor: key: cord-029106-gkck1u4y authors: Ma, Lina title: COVID-19 Prevention: Use of Self-Reported Tools to Screen Frail Older Adults date: 2020-07-13 journal: J Nutr Health Aging DOI: 10.1007/s12603-020-1446-9 sha: doc_id: 29106 cord_uid: gkck1u4y nan frailty tools to predict worse outcomes in both community and emergency settings (5, 6) , should be used to identify frailty among older adults.
    keywords: adults
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        item: #112 of 7819
          id: cord-029172-fctcfoak
      author: Romano, John L.
       title: Politics of Prevention: Reflections From the COVID-19 Pandemic
        date: 2020-07-13
       words: 8403
      flesch: 34
     summary: This discussion is followed by the influence of political considerations on prevention interventions, whether smaller scale interventions or major global interventions recommended to contain COVID-19. They are presented as examples of theories with long histories studying prevention interventions and relevant within a COVID-19 prevention context.
    keywords: community; covid-19; example; health; interventions; pandemic; prevention; psychology; public; recommendations; research; school; science; states; united; virus
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        item: #113 of 7819
          id: cord-029226-eagbwk7j
      author: Williamson, Brian
       title: Beyond COVID‐19 lockdown: A Coasean approach with optionality
        date: 2020-06-29
       words: 2597
      flesch: 46
     summary: The combination of low health risk for younger people from COVID-19 with disproportionately high economic and social costs from the current policy response suggests that a more targeted policy response is desirable. Reciprocity arises because either those at higher risk can isolate themselves or those who might infect them but are at lower risk can be locked down to reduce the spread of COVID-19.
    keywords: covid-19; health; immunity; life; risk; social
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        item: #114 of 7819
          id: cord-029332-yn603pvb
      author: None
       title: Full Issue PDF
        date: 2020-07-15
       words: 11336
      flesch: 34
     summary: To recognize cardiovascular complications among COVID-19 patients. We are also learning that acute kidney injury is quite prevalent and highly associated with mortality in COVID-19 patients (6).
    keywords: acute; cardiac; cardiovascular; care; case; china; coronavirus; covid-19; diagnosis; disease; dysfunction; failure; figure; heart; history; infection; mortality; myocarditis; pandemic; patients; pneumonia; risk; sars; syndrome
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        item: #115 of 7819
          id: cord-029419-b0w9nomq
      author: Matthews, Adam
       title: Review of Mark Honigsbaum (2020). The Pandemic Century—A History of Global Contagion from the Spanish Flu to Covid-19: Cambridge, MA: Penguin. 321 pp. ISBN 9780753558287
        date: 2020-07-20
       words: 3959
      flesch: 50
     summary: Epidemiologists set out on asking who, where, when, how and what, to understand the biological make-up of new diseases. The questions then, which The Pandemic Century (Honigsbaum 2020) illustrates is whether to take a posthuman perspective and pull back from technological and human development and reduce ecological disruption and work with the natural environment as equals or to push on unabated with technological developments to go beyond what has been done already to 'fix' ourselves and the planet, including new viral outbreaks.
    keywords: century; covid-19; disease; honigsbaum; media; new; outbreak; pandemic; sars; virus
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        item: #116 of 7819
          id: cord-029466-9sy6icrm
      author: Ramadan, Ahmad Riad
       title: Tales of a department: how the COVID-19 pandemic transformed Detroit’s Henry Ford Hospital, Department of Neurology—part I: the surge
        date: 2020-07-12
       words: 4350
      flesch: 47
     summary: With the ensuing reduction in our NICU census and everincreasing demand to staff COVID-19 medical units, we volunteered a lean rounding model in our unit, allowing our rotating trainees to be deployed to the ED or COVID-19 ICUs. They also had 10 days off between COVID-19 unit rotations to recuperate.
    keywords: care; covid-19; department; health; march; medical; neurology; pandemic; patients; research; residents; staff; unit
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        item: #117 of 7819
          id: cord-029545-fspjpmsr
      author: None
       title: Council of International Neonatal Nurses (COINN) News page
        date: 2020-07-22
       words: 4976
      flesch: 60
     summary: This meeting was very fruitful to obtain a mapping of COVID-19 neonatal nursing care, transfer material worked on by experts from different autonomous communities and create lines of work appropriate to real needs. gallagher@ucl.ac.uk, Alex Mancini (Chelsea & Westminster NHS FT) a. mancini@nhs.net or Julia Petty (UK NNA) j.petty@herts.ac.uk The Journal of Neonatal Nursing invites you to publish… 'Advancing neonatal nursing care, education and research globally' The Journal of Neonatal Nursing serves both the UK Neonatal Nurses Association (NNA) and COINN.
    keywords: care; covid-19; health; neonatal; nicu; nurses; nursing; parents; time; unit
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        item: #118 of 7819
          id: cord-029547-9ei1ram3
      author: Li, Jingwei
       title: The epidemiology and therapeutic options for the COVID-19
        date: 2020-05-28
       words: 7859
      flesch: 39
     summary: Then, the quantity of COVID-19 patients increased rapidly after Chinese New Year. According to the data collected in January 2020, the incubation stage of COVID-19 patients ranges between 2 and 14 days, and its average is about 5 days (95% credible interval: 4.2-6.0) when implementing the best-fit lognormal distribution.
    keywords: cells; characteristics; china; clinical; coronavirus; cov-2; covid-19; disease; infection; novel; patients; pneumonia; sars; symptoms; treatment; vaccine
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        item: #119 of 7819
          id: cord-029568-0xyz5z5b
      author: Gogia, Spriha
       title: Covid-19 X-Curves: Illness Hidden, Illness Deferred
        date: 2020-05-29
       words: 1027
      flesch: 40
     summary: Some Covid-19 patients who would have otherwise been in an ICU did receive intensive care on hospital wards, making this a conservative estimate of Covid-19 patients with critical illness. Covid-19 patient volume began to grow in mid-March, cresting at 712 patients in mid-April.
    keywords: covid-19; icu; illness; patients
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        item: #120 of 7819
          id: cord-029590-95rp9u93
      author: Kumar, Pooja
       title: Reassessing Covid-19 Needs: How Providers Can Reexamine Their Surge Capacity, Supply Availability, Workforce Readiness, and Financial Resiliency
        date: 2020-05-07
       words: 2160
      flesch: 32
     summary: key: cord-029590-95rp9u93 authors: Kumar, Pooja; Kattan, Omar; Broome, Bede; Singhal, Shubham title: Reassessing Covid-19 Needs: How Providers Can Reexamine Their Surge Capacity, Supply Availability, Workforce Readiness, and Financial Resiliency date: 2020-05-07 journal: NEJM Catal Innov Care Deliv DOI: 10.1056/cat.20.0112 sha: doc_id: 29590 cord_uid: 95rp9u93 As the coronavirus pandemic continues to create unprecedented challenges for health care providers, it is especially important to create and, as needed, revise plans to mitigate disruption to the degree possible. Another example of collaboration is the development of supply-demand aggregation platforms by many organizations: Project N95 is one of many that was created to serve as a national clearinghouse to connect health care providers with critical equipment (see Appendix).
    keywords: capacity; care; covid-19; health; patients; providers; workforce
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        item: #121 of 7819
          id: cord-029596-tdrhcq7z
      author: Mjåset, Christer
       title: On Having a National Strategy in a Time of Crisis: Covid-19 Lessons from Norway
        date: 2020-05-06
       words: 1853
      flesch: 42
     summary: Because the single-payer plan covers every type of advanced treatment apart from adult dental care, it is debated whether this insurance is necessary.6 For every Norwegian, there is a cap on the annual co-payments tied to medical treatment and subscription drugs, approximately $240 (USD, based on the April 12, 2020, exchange rate),7 no insurance premiums, and no surprise bills, meaning health care in Norway is regarded as a right, not something you buy. The health authorities have been criticized for being too slow to impose quarantines, entry bans, and other restrictions for citizens, and for having lacked supplies of critical equipment necessary to meet a pandemic the size of the current one, which in mid-March for a short while led to testing restrictions.27 -29 Still, the strength of the Norwegian Covid-19 response seems to be the early decision to pursue a national strategy, to coordinate efforts across regions as well as primary and specialized care, and the general willingness to listen to and trust the health authorities in a time of crisis.30 This trust has, by many, been pointed out to be deeply rooted in Norwegian mentality,31 although it is also a feature that is easily facilitated by the nature of a single-payer system with universal health care.
    keywords: care; covid-19; health; national; norwegian; people; public
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        item: #122 of 7819
          id: cord-029606-2z1tw4xo
      author: John, Janice
       title: Developing an Intensive Community Covid-19 Management Strategy: Helping Our Patients Access Patient-Centered Care across a Continuum of Covid-19 Disease Needs
        date: 2020-05-27
       words: 3164
      flesch: 45
     summary: Yet, to optimally manage resources, telemedicine needs to be optimized to assess Covid-19 patients, and needs to be coordinated with in-person evaluation and a population health management approach to ensure the safety of patients. These providers are organized in two teams that take on panels of suspected and confirmed Covid-19 patients who are at higher risk for severe disease.
    keywords: care; clinic; community; covid-19; disease; management; patients
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        item: #123 of 7819
          id: cord-029609-zh2ah34g
      author: Hamilton, Barbara C.S.
       title: Developing Perioperative Covid-19 Testing Protocols to Restore Surgical Services
        date: 2020-06-19
       words: 3165
      flesch: 36
     summary: The group continued to be the steward of all major Covid-19 perioperative decision and determined to implement its SARS-CoV-2 testing procedure for surgical patients in a stepwise manner to account for practical conditions that blocked a full rollout on a single date. With the unresolved uncertainties in the supply chain (for reagents and nasal swabs, for example) and that asymptomatic testing for surgical patients would add between 50 and 250 patients (normal daily volumes), we recognized that full implementation had the potential to quickly overwhelm the testing system.
    keywords: care; communication; covid-19; operating; patients; surgery; testing
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        item: #124 of 7819
          id: cord-029620-jwpl2jq9
      author: Heyworth, Leonie
       title: Expanding Access through Virtual Care: The VA’s Early Experience with Covid-19
        date: 2020-07-01
       words: 2824
      flesch: 33
     summary: While VA was an early adopter of telehealth and was the nation's first health system to employ a chief telehealth officer in 1999, the vast majority of VA outpatient care continued to be face-to-face visits through February 2020. While VA was an early adopter of telehealth and was the nation's first health system to employ a chief telehealth officer in 1999, the vast majority of VA outpatient care continued to be face-to-face visits through February 2020.
    keywords: care; covid-19; health; home; telehealth; video; visits
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        item: #125 of 7819
          id: cord-029630-46d1cfy0
      author: Nacoti, Mirco
       title: At the Epicenter of the Covid-19 Pandemic and Humanitarian Crises in Italy: Changing Perspectives on Preparation and Mitigation
        date: 2020-03-21
       words: 905
      flesch: 47
     summary: In hospitals, health care workers and ancillary staff are alone, trying to keep the system operational. This approach would limit hospitalization to a focused target of disease severity, thereby decreasing contagion, protecting patients and health care workers, and minimizing consumption of protective equipment.
    keywords: care; covid-19; health
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        item: #126 of 7819
          id: cord-029631-hdqzjdz3
      author: Parodi, Stephen
       title: Kaiser Permanente’s System Capabilities to Suppress Covid-19
        date: 2020-06-09
       words: 2377
      flesch: 24
     summary: If Covid-19 suppression is to succeed, our collective efforts will require an unprecedented level of coordination among governments, public health agencies, health care systems, industry partners, and community groups. If Covid-19 suppression is to succeed, our collective efforts will require an unprecedented level of coordination among governments, public health agencies, health care systems, industry partners, and community groups.
    keywords: care; covid-19; disease; health; kaiser; permanente; suppression
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        item: #127 of 7819
          id: cord-029654-pq2y6eek
      author: Rubio, José Luis Callejas
       title: One world, one health: The novel coronavirus COVID-19 epidemic()
        date: 2020-07-23
       words: 363
      flesch: 27
     summary: One world, one health: The novel coronavirus COVID-19 epidemic Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease Epub ahead of print Digestive Symptoms in COVID-19 Patients With Mild Disease Severity: Clinical Presentation, Stool Viral RNA Testing, and Outcomes COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options Immunomodulatory therapy for the management of severe COVID-19 But what can be inferred from its reading, especially by readers who are not involved in the diagnosis, clinical monitoring and treatment of this disease, is that it is a purely an infectious disease, which basically produces a viral condition that can be complicated by a more or less severe pneumonia with respiratory distress, and whose treatment is based on the use of antiviral drugs.
    keywords: covid-19
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        item: #128 of 7819
          id: cord-029672-y2ii6r3u
      author: Van Assche, Ari
       title: From the editor: COVID-19 and international business policy
        date: 2020-07-24
       words: 3662
      flesch: 35
     summary: The geography of innovation: local hotspots and global innovation networks Shaping the formation of university-industry research collaborations: What type of proximity does really matter Economic policy responses to a pandemic: Developing the COVID-19 economic stimulus index Protectionism, state discrimination, and international business since the onset of the Global Financial Crisis Sicken thy neighbour: The initial trade policy response to COVID-19 How big business is joining the fight against COVID-19 The wealth of cities: Agglomeration economies and spatial equilibrium in the United States An unintended crisis: 29672 cord_uid: y2ii6r3u We introduce a special collection of papers on COVID-19 and international business policy that looks at the global policy challenge from different perspectives.
    keywords: business; costs; covid-19; face; knowledge; mnes; pandemic; policy; production; trade
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        item: #129 of 7819
          id: cord-029710-ythz9ax0
      author: Homayounieh, Fatemeh
       title: CT Radiomics, Radiologists and Clinical Information in Predicting Outcome of Patients with COVID-19 Pneumonia
        date: 2020-07-23
       words: 3096
      flesch: 37
     summary: Pneumonia Feasibility of CT radiomics to predict treatment response of individual liver metastases in esophagogastric cancer patients Unsupervised machine learning of radiomic features for predicting treatment response and overall survival of early stage non-small cell lung cancer patients treated with stereotactic body radiation therapy Novel Quantitative Imaging for Predicting Response to Therapy: Techniques and Clinical Applications Radiomics predicts survival of patients with advanced non-small cell lung cancer undergoing PD-1 blockade using Nivolumab Diagnostic performance between CT and initial real-time RT-PCR for clinically Radiomics differentiated chest CT in outpatient vs inpatient with an AUC of 0.84 (p<0.005), while radiologists’ interpretations of disease extent and opacity type had an AUC of 0.69 (p<0.0001).
    keywords: chest; covid-19; lung; patients; pneumonia; radiomics; study
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        item: #130 of 7819
          id: cord-029813-o2uzcuai
      author: Rusconi, Stefano
       title: COVID-19: studying the global pandemic – foreword
        date: 2020-07-27
       words: 2727
      flesch: 36
     summary: All SARS- CoV-2 five key proteins have a large homology with SARS-CoV from bats, although the lowest homology was with the S protein, which showed the highest amino acid homology with bat SARS RaTG13 reaching 97.71%. Tan et al. discuss the critical public health issue of the extent to which asymptomatically infected persons are transmitting SARS-CoV-2 to others and contrast the currently available data with the epidemiologic findings in SARS and MERS
    keywords: authors; cov-2; covid-19; rna; sars; virus
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        item: #131 of 7819
          id: cord-029859-fhm0d9t9
      author: Yue, Ling
       title: How psychiatrists coordinate treatment for COVID-19: a retrospective study and experience from China
        date: 2020-07-21
       words: 2948
      flesch: 38
     summary: Patients with mental health disorders in the COVID-19 epidemic Anxiety, depression and somatic symptoms in COVID-19 patients Care for critically ill patients with COVID-19 Systematic review of psychological first aid Psychological crisis intervention during the outbreak period of new coronavirus pneumonia from experience in Shanghai Comprehensive treatment and management of corona virus disease 2019: The psychiatric diagnoses for the 84 patients with COVID-19 who used mental health consultation were as follows: acute stress reaction (39.3%), sleep disorders (33.3%), anxiety state (15.5%), depression state or major depression (7.1%), and delirium (4.8%) (see table 4 ).
    keywords: consultation; covid-19; health; mental; patients; psychiatric
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        item: #132 of 7819
          id: cord-029863-f3bn550o
      author: Jassi, Amita
       title: OCD and COVID-19: a new frontier
        date: 2020-07-14
       words: 5646
      flesch: 40
     summary: Identifying OCD in the context of COVID-19 OCD is a common disorder affecting around 1.6% of adults (Kessler et al., 2005) and 1-3% of children and adolescents (Heyman et al., 2001; Valleni-Basile et al., 1995) . Therapists should consider whether CBT-informed work with parents to contain and reduce their accommodation of OCD symptoms, for example, may have greater benefits in such situations than individual CBT.
    keywords: cbt; context; covid-19; disorder; e.g.; ocd; people; risk; tasks; uncertainty
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        item: #133 of 7819
          id: cord-029865-zl0romvl
      author: Bowe, Emily
       title: Learning from lines: Critical COVID data visualizations and the quarantine quotidian
        date: 2020-07-27
       words: 4113
      flesch: 44
     summary: By understanding the origins of epidemiological data and reinforcing the importance of context and non-quantitative forms of data, we can push for a richer, more diverse discourse through data visualization. First, they offer tutorials and tools for both dataviz practitioners and their publics to encourage critical thinking about how COVID-19 data is sourced and modeled—and to consider which subjects are not interpellated in those data sets, and why not.
    keywords: coronavirus; covid-19; data; figure; making; maps; new; pandemic; projects; public; quarantine; visualizations; www
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        item: #134 of 7819
          id: cord-029880-mhmvc0kq
      author: Sy, Charlle
       title: Policy Development for Pandemic Response Using System Dynamics: a Case Study on COVID-19
        date: 2020-07-29
       words: 2588
      flesch: 37
     summary: Furthermore, despite its unpredictability, there is evidence that suggests externalities such as fear-driven behavioral changes could potentially be the largest contributor to the economic costs of disease outbreaks. Mathematical and statistical models have been used to gain a better understanding of disease outbreaks and aid in emergency preparedness and response decision-making.
    keywords: covid-19; disease; dynamics; health; outbreak; pandemic; quarantine; system
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        item: #135 of 7819
          id: cord-029885-vawqjfij
      author: Piccini, Jonathan P.
       title: EP News: Quality Improvement and Outcomes
        date: 2020-07-30
       words: 630
      flesch: 37
     summary: The authors conclude that while mobile cardiac outpatient telemetry has not been approved for QTc monitoring for patients with atrial fibrillation or flutter, QRS duration >160 msec, or T-wave <5% of the peak QRS amplitude, their single-center study suggests that innovative management of QTc monitoring is possible under the resource-constrained conditions of a pandemic. In this issue of Heart Rhythm, we continue this quarterly feature highlighting developments and advances in quality improvement in the delivery of heart rhythm care.
    keywords: covid-19; heart; pandemic
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        item: #136 of 7819
          id: cord-029898-2t9mif9k
      author: Chaganti, Shikha
       title: Automated Quantification of CT Patterns Associated with COVID-19 from Chest CT
        date: 2020-07-29
       words: 4110
      flesch: 50
     summary: A new method segments regions of CT abnormalities associated with COVID-19 and computes (PO, PHO), as well as (LSS, LHOS) severity scores. However, most patients with COVID-19 do seem to exhibit CT abnormalities and the extent of these changes seem to correlate with disease severity.
    keywords: abnormalities; chest; covid-19; disease; ground; lung; pho; segmentation
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        item: #137 of 7819
          id: cord-029906-vfkqmri7
      author: Kirigia, Joses Muthuri
       title: The monetary value of human life losses associated with COVID-19 in Turkey
        date: 2020-07-08
       words: 2619
      flesch: 43
     summary: The TMVHL equals the sum of monetary values of human lives lost (MVHL) across nine age groups. The 4807 human life losses from COVID-19 had a TMVHL of Int$1,098,469,122; and a mean of Int$228,514 per human life.
    keywords: covid-19; discount; health; life; turkey; value
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        item: #138 of 7819
          id: cord-029967-dnyhn4bt
      author: Alpert, Joseph S.
       title: We Will Never Give Up
        date: 2020-08-01
       words: 689
      flesch: 68
     summary: The hoped-for influenza-like course has not developed, and many opine that we will be fighting this scourge for many months or even years to come. We are confident that in the future when we have conquered SARS COVID-19, and conquer it we will, many stories will be told of the 2019-20 pandemic and our various roles in the conquest.
    keywords: covid-19; hospital
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        item: #139 of 7819
          id: cord-030018-sabmw7wf
      author: El-Shabrawi, Mortada
       title: Infant and child health and healthcare before and after COVID-19 pandemic: will it be the same ever?
        date: 2020-08-04
       words: 3274
      flesch: 44
     summary: We have to identify and assess the different factors that have either direct or indirect effects on child health and healthcare due to COVID-19 pandemic and focus on the serious effects. So far, the COVID-19 crisis has had a great impact on child health and healthcare all over the world, not only from the medical aspect, but also from the social, psychologic, economic, and educational aspects.
    keywords: adults; children; covid-19; disease; health; healthcare; infection; pandemic; world
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        item: #140 of 7819
          id: cord-030051-kzkpu94o
      author: O’Brien, Michelle Mary Clare
       title: Opportunistic Diagnosis of Extensive Pulmonary Embolus Following “COVID-19 Blood Battery” in Very Frail Older Patients
        date: 2020-08-04
       words: 2516
      flesch: 42
     summary: The D-dimer assay Biomarkers for the diagnosis of venous thromboembolism: D-dimer, thrombin generation, procoagulant phospholipid and soluble P-selectin Age-adjusted D-dimer cut-off leads to more efficient diagnosis of venous thromboembolism in the emergency department: a comparison of four assays Diagnosis of pulmonary embolism in the elderly: adherence to guidelines and age-adjusted D-dimer concentration values D-dimer testing: laboratory aspects and current issues Ageadjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS) The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC) Thromboembolic risk and anticoagulant therapy in COVID-19 patients: Emerging evidence and call for action ISTH interim guidance on recognition and management of coagulopathy in COVID-19 Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-dimer A new method of classifying prognostic comorbidity in longitudinal studies: development and validation A global clinical measure of fitness and frailty in elderly people Similarity in case fatality rates (CFR) of COVID-19/SARS-COV-2 in Italy and China Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Prevalence of pulmonary embolism among patients hospitalized for syncope Prevalence of pulmonary embolism in patients with syncope Detection of SARS-CoV-2 in different types of clinical specimens Atypical presentation of COVID-19 in a frail older person Ethical Standards: Informed consent from all patients. A “COVID-19 blood battery”, designed to increase the efficiency of evaluation of COVID-19 suspected patients is used in our institution.
    keywords: covid-19; dimer; patients; pulmonary; symptoms
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        item: #141 of 7819
          id: cord-030138-250u4nxi
      author: Clark-Ginsberg, Aaron
       title: Maintaining critical infrastructure resilience to natural hazards during the COVID-19 pandemic: hurricane preparations by US energy companies
        date: 2020-08-06
       words: 3859
      flesch: 24
     summary: Given the parallels between the US electric grid and other critical infrastructure inside and outside of the United States, answering these questions could help improve critical infrastructure resilience to concurrent crisis and disasters broadly, across multiple infrastructures and geographic locations. key: cord-030138-250u4nxi authors: Clark-Ginsberg, Aaron; Rueda, Ismael Arciniegas; Monken, Jonathon; Liu, Jay; Chen, Hong title: Maintaining critical infrastructure resilience to natural hazards during the COVID-19 pandemic: hurricane preparations by US energy companies date: 2020-08-06 journal: J Infrastruct Preserv Resil DOI: 10.1186/s43065-020-00010-1 sha: doc_id: 30138 cord_uid: 250u4nxi The COVID-19 pandemic has the potential to compromise the ability of critical infrastructure utilities to respond to or mitigate natural hazards like wildfires and hurricanes.
    keywords: control; covid-19; energy; grid; hazards; infrastructure; pandemic; pjm; resilience
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        item: #142 of 7819
          id: cord-030191-tekgcthp
      author: Suchá, Dominika
       title: Suboptimal Quality and High Risk of Bias in Diagnostic Test Accuracy Studies on Chest Radiography and Computed Tomography in the Acute Setting of the COVID-19 Pandemic: A Systematic Review
        date: 2020-07-30
       words: 5038
      flesch: 35
     summary: Mean number of reported STARD items was 12/34 (35%) for all studies (Figure- Based on the GRADE framework the certainty of evidence for the totality of CT test accuracy studies for COVID-19 diagnosis was rated very low for both sensitivity and specificity estimates ( Table 7) . Study design, risk of bias, and indirectness in rating the certainty across a body of evidence for test accuracy Sources of variation and bias in studies of diagnostic accuracy: a systematic review A systematic review classifies sources of bias and variation in diagnostic test accuracy studies STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration GRADE guidelines: 21 part 2.
    keywords: accuracy; bias; coronavirus; covid-19; disease; patients; risk; studies; study; test
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        item: #143 of 7819
          id: cord-030192-ebsh62ll
      author: Winant, Abbey J.
       title: Thoracic Imaging Findings of Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with COVID-19: What Radiologists Need to Know Now
        date: 2020-07-30
       words: 4308
      flesch: 28
     summary: 4, 5, 13, 16 Given the current lack of available information related to the thoracic imaging findings of pediatric MIS-C associated with COVID-19 infection, the purpose of this article is to provide an up-to-I n p r e s s date review of the clinical and imaging features of pediatric MIS-C associated with COVID-19 infection, compared with acute pediatric COVID-19 infection, with an emphasis on thoracic imaging findings. In addition, while the incidence of Kawasaki disease is highest in Asia, strikingly, there have been no reported cases of MIS-C in Asia, despite being an early hotspot of COVID-19 infection, with some of the earliest published series on acute pediatric COVID-19 infection emerging from China.
    keywords: children; covid-19; disease; imaging; infection; mis; patients; pediatric
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        item: #144 of 7819
          id: cord-030197-ohz1i5uh
      author: Tosato, Matteo
       title: “Say Ninetynine”: It’s Never Too Late to Recover from COVID-19
        date: 2020-08-07
       words: 965
      flesch: 44
     summary: We have recently observed a demographic shift towards older ages in COVID-19 patients admitted to our COVID Hospital. Fatality rates vary between studies, but large cohort observational studies reported a greater disease severity in older patients (1) (2) .
    keywords: covid-19; disease; patient
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        item: #145 of 7819
          id: cord-030228-mx9ycsvo
      author: Momaya, Kirankumar S.
       title: Return from COVID-19: Thinking Differently About Export Competitiveness and Sustainability
        date: 2020-08-09
       words: 4742
      flesch: 47
     summary: Practices such as 'य़ोग और प्ाणायाम' (yoga and pranayam) can help improve our health to face such crises. Accepting such crisis due to virus or other pathogens (नवषाणु ) as a new normal, evolve a plan to help yourself, family, friends and other groups to live with it safely.
    keywords: action; competitiveness; context; countries; covid-19; crisis; e.g.; india; lap; research; sap
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        item: #146 of 7819
          id: cord-030254-eevqclsy
      author: Mehta, Chitra
       title: Management of Coronavirus 2019
        date: 2020-04-24
       words: 4039
      flesch: 51
     summary: 14 The initial approach should be early suspicion, early recognition, immediate isolation, and institution of infection control precautions of COVID-19 patients. The use of acetaminophen or paracetamol over other antipyretics is recommended for temperature control in COVID-19 patients.
    keywords: coronavirus; cov-2; covid-19; days; disease; infection; patients; risk; sars; use
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        item: #147 of 7819
          id: cord-030256-muah207b
      author: Kapoor, Poonam Malhotra
       title: COVID-19 Thrombosis: An Unsolved Mystery
        date: 2020-07-24
       words: 1651
      flesch: 42
     summary: It is widely acknowledged that the majority of COVID-19 patients, especially those with severe disease, are characterized by lymphocytopenia. COVID-19: consider cytokine storm syndromes and immunosuppression Current concepts in the diagnosis and management of cytokine release syndrome Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia COVID-19 ECMO myths busted United States Center for Disease Control interim guidance for clinical management of COVID-19 patients with and without acute respiratory distress syndrome Intubation and ventilation amid the COVID-19 outbreak: Wuhan's experience
    keywords: cells; covid-19; cytokine; ecmo; patients; syndrome; virus
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        item: #148 of 7819
          id: cord-030296-4xthry9c
      author: Barbieri, Paolo
       title: What can we learn about reshoring after Covid-19?
        date: 2020-08-11
       words: 3287
      flesch: 43
     summary: Starting from the previous knowledge provided in the literature, we can recognize that Covid-19 can be associated with the role of a trigger for reshoring decisions. Since much of business strategy can be conceived of as balancing of risk and return, existing tools such as decision trees and Monte Carlo risk analysis approach, see Samson and Gloet (2018) , can be usefully applied to model and evaluate reshoring decisions, in such a way as to explicitly account for uncertainty in turbulent times.
    keywords: chain; covid-19; decision; manufacturing; reshoring; supply; term
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        item: #149 of 7819
          id: cord-030378-f9hf9plf
      author: Madsen, Tracy E.
       title: Unique Risks and Solutions for Equitable Advancement during the Covid-19 Pandemic: Early Experience from Frontline Physicians in Academic Medicine
        date: 2020-07-20
       words: 3157
      flesch: 27
     summary: Furthermore, because women physicians do not hold the majority of executive leadership positions, they are less likely to get asked or chosen for even temporary leadership positions during a health care crisis, and they are often not in positions to advocate for new policies to break these catch-22 cycles. These data demonstrated that health care workers who are SARS survivors showed significantly higher stress levels one year after the outbreak and had higher depression, anxiety, and posttraumatic symptoms than non-health care worker survivors of infection.9 Emerging data show that not only are the psychological impacts of Covid-19 more pronounced among women in the general population,10 but even more so on women health care workers.11 Studies looking at the impact on women physicians specifically have not been published to date, but will be critical in order to assess the long-term psychological impact of Covid-19.
    keywords: academic; care; covid-19; gender; health; physicians; risk; women
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        item: #150 of 7819
          id: cord-030382-pqf899k7
      author: Smith, Shaun
       title: The Heroes and Heroines: Supporting the Front Line in New York City During Covid-19
        date: 2020-07-15
       words: 2934
      flesch: 48
     summary: Employee services are a vital component to preserving a healthy workforce. Re-thinking the work environment demands virtual employee services: During the Covid-19 pandemic, healthcare employees have busy, stressful schedules.
    keywords: care; covid-19; crisis; employees; health; nyp; pandemic; services; support
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        item: #151 of 7819
          id: cord-030506-mqsgqfbs
      author: Bonilla-Molina, Luis
       title: Covid-19 on Route of the Fourth Industrial Revolution
        date: 2020-08-15
       words: 2479
      flesch: 42
     summary: Covid-19 lockdowns and quarantines have opened up various strategies and approaches focused on the model of home education. Based on the promise of reducing this expenditure, the model of home education becomes a Trojan horse to initiate a neo-privatization of education.
    keywords: covid-19; education; global; home; model; pandemic; world
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        item: #152 of 7819
          id: cord-030529-2wkes9nk
      author: Goggin, Gerard
       title: COVID-19 apps in Singapore and Australia: reimagining healthy nations with digital technology
        date: 2020-08-14
       words: 7372
      flesch: 44
     summary: The Act creates several serious offences dealing with COVID app data, including 'non-permitted, use, or disclosure', 'uploading COVID app data without consent', 'retaining or disclosing uploaded data outside Australia', 'decrypting encrypted COVID app data' and 'requiring participation in relation to COVIDSafe' (Privacy Amendment, 2020: 4). 'COVID app data' is defined as 'data relating to a person . . .
    keywords: app; apps; australia; concerns; contact; covid-19; covidsafe; data; government; health; pandemic; people; privacy; public; singapore; tracetogether; use
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        item: #153 of 7819
          id: cord-030556-usyvz5fj
      author: Dave, M.
       title: Open-book examinations
        date: 2020-08-14
       words: 735
      flesch: 34
     summary: Traditionally, closed book examinations such as multiple-choice questions, where learners are not permitted to have any supportive material with them, are the preferred format for UK dental courses. More Sir, loss of smell (anosmia) and loss of taste (ageusia) are symptoms that were identified in COVID-19 patients at the early stage of illness.
    keywords: book; examinations; patients
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        item: #154 of 7819
          id: cord-030565-jwqod8q5
      author: Ali, Rasha Mostafa Mohamed
       title: Radiological findings spectrum of asymptomatic coronavirus (COVID-19) patients
        date: 2020-08-18
       words: 2321
      flesch: 46
     summary: As the COVID-19 pandemic continues to claim lives across the globe, early diagnosis of asymptomatic COVID-19 patients is essential as they act as a covert transmitter. The aims of our study are to understand the imaging spectrum of asymptomatic COVID-19 positive patients and to facilitate the detection and isolation of asymptomatic patients who act as the asymptomatic transmitter of the disease.
    keywords: asymptomatic; covid-19; patients; study
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        item: #155 of 7819
          id: cord-030578-8c77d59p
      author: Combs, Joshua C.
       title: SARS CoV-2: a review of current treatment regimens
        date: 2020-08-11
       words: 625
      flesch: 27
     summary: Vitamin C, with its ability to support lymphocyte proliferation/neutrophil phagocytosis and vitamin D, with its ability to reduce viral replication rates through induction of antimicrobial peptides, are currently being evaluated regarding their efficacy in COVID-19 treatment key: cord-030578-8c77d59p authors: Combs, Joshua C. title: SARS CoV-2: a review of current treatment regimens date: 2020-08-11 journal:
    keywords: covid-19; treatment
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        item: #156 of 7819
          id: cord-030600-0o7xafqz
      author: Fonseka, T
       title: The effects of COVID-19 on training within urology: Lessons learned in virtual learning, human factors, non-technical skills and reflective practice
        date: 2020-08-17
       words: 3780
      flesch: 43
     summary: In the USA, Vargo et al. 14 have created a structured framework through the use of virtual learning to continue urology training despite lower surgical volumes and the inability to have face-to-face meetings during the pandemic. Impact of the COVID-19 pandemic on urology residency training in Italy Surgery specific management of ARCPs during COVID-19 COVID-19 and Trainee Progression in 2020 (update I) Unskilled and unaware of it: How difficulties in recognizing one's own incompetence lead to inflated self-assessments Impact of performance in a mandatory postgraduate surgical examination on selection into specialty training COVID-19 and the urology match: Perspectives and a call to action Is there a need for an undergraduate urological curriculum? Medical students' exposure to urology in the undergraduate curriculum, a web based survey The urological foot soldier: Are we equipping our foundation-year doctors Avoidable iatrogenic complications of urethral catheterization and inadequate intern training in a tertiary-care teaching hospital Foundation Year 1 doctors' experience and confidence in catheterisation: A multicentre survey The cost of a number: Can you afford to become a surgeon? Clinic Akron general urology residency program's COVID-19 experience Current status of simulation and training models in urological surgery: A systematic review Adapting urology residency training in the COVID-19 era Slowdown of urology residents' learning curve during the COVID-19 emergency The impact of COVID-19 on Canadian urology residents COVID-19 webinar series -Royal College of Surgeons The Royal College of Anaesthetists.
    keywords: covid-19; face; pandemic; practice; skills; surgeons; trainees; training; urology
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        item: #157 of 7819
          id: cord-030636-wpjmwwpu
      author: None
       title: Dear Editor,
        date: 2020-08-19
       words: 996
      flesch: 38
     summary: Survival status and clinical data were compared with a control group of COVID-19 patients aged < 70 years (n=109). [4] [5] [6] Further, the majority of data at the moment available often originating from Chinese surveys where elderly patients accounted only for a very limited part of the total.
    keywords: clinical; covid-19; patients
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        item: #158 of 7819
          id: cord-030730-ciatihn0
      author: Ahuja, Sakshi
       title: Deep transfer learning-based automated detection of COVID-19 from lung CT scan slices
        date: 2020-08-21
       words: 5418
      flesch: 47
     summary: The output activation is obtained by passing the testing image (COVID-19 positive CT scan image) through the best performing ResNet18 pre-trained network. SqueezeNet is used to investigate the performance of the binary classification of chest CT images on smaller deep learning neural networks.
    keywords: chest; covid-19; data; detection; disease; images; learning; model; pre; scan; transfer
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        item: #159 of 7819
          id: cord-030771-0x0d56fb
      author: Sorenson, Corinna
       title: Building A Better Health Care System Post-Covid-19: Steps for Reducing Low-Value and Wasteful Care
        date: 2020-08-21
       words: 2813
      flesch: 31
     summary: CMS could direct additional Covid-19 relief funding to hospitals and providers who agree to pilot new models for health care reopening that actively seek to aid in the pandemic response, and who participate in alternative payment models to build a stronger health care system.31 More broadly, CMS should work with health care providers and payers to assess how and where relaxed telehealth regulations have worked particularly well to align care with patient need, using it as the basis for deciding how to continue to encourage effective telehealth. Other experts have identified overuse practices in hospital medicine that can lead to harm of both patients and health care workers.12 A range of resources are available to help providers and health systems develop these lists, including Choosing Wisely and the U.S. Preventive Services Task Force recommendations and the Task Force on Low-Value Care's top five services to.13 -15
    keywords: care; covid-19; health; patients; providers; services; systems; value
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        item: #160 of 7819
          id: cord-030909-6if3qquj
      author: None
       title: Perspectives on the Economics of the Environment in the Shadow of Coronavirus
        date: 2020-08-27
       words: 28261
      flesch: 43
     summary: The economic crisis can end up having long-run negative consequences for the environment if, as a result, regulations and environmental policies are relaxed or if institutions are weakened. Acceptability of environmental policies by companies is a necessary condition for their implementation.
    keywords: air; carbon; case; change; climate; climate change; companies; conditions; consumption; countries; covid-19; covid-19 pandemic; crisis; data; demand; economy; effects; emissions; energy; environmental; et al; european; example; food; global; green; health; impact; increase; measures; need; new; pandemic; period; policies; policy; public; recovery; research; resource; supply; term; time; use; world
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        item: #161 of 7819
          id: cord-030927-wo8r8zny
      author: Collins, Curtis D
       title: Perspectives from the frontline: A pharmacy department’s response to the COVID-19 pandemic
        date: 2020-06-22
       words: 4478
      flesch: 32
     summary: A 32-bed overflow special pathogens unit, previously equipped for management of critical care patients during a disaster response, was opened. Pharmacists intervened to address a wide scope of medication-related issues, likely contributing to improved management of COVID-19 patients.
    keywords: antimicrobial; care; covid-19; interventions; management; pandemic; patients; pharmacists; pharmacy; study
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        item: #162 of 7819
          id: cord-030934-t7akdu6x
      author: Bahrami, Afsane
       title: Genetic and pathogenic characterization of SARS-CoV-2: a review
        date: 2020-08-26
       words: 6490
      flesch: 36
     summary: SARS-CoV-2 shares 80% nucleotide identity to SARS-CoV. The S, E, M, N and ORF3a genes of SARS-CoV-2 are predicted to be 3822, 228, 669, 1260 and 828 nucleotides in length, respectively.
    keywords: acute; cells; coronavirus; cov-2; covid-19; covs; disease; human; infection; novel; patients; protein; response; sars; spike; treatment
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        item: #163 of 7819
          id: cord-030956-wire1g2n
      author: Kolta, Marian Fayek
       title: COVID-19 variant radiological findings with high lightening other coronavirus family (SARS and MERS) findings: radiological impact and findings spectrum of corona virus (COVID-19) with comparison to SARS and MERS
        date: 2020-08-28
       words: 2639
      flesch: 44
     summary: The majority of SARS positive patients show progressive multifocal distribution, in the followup imaging, of which 75% of patients show bilateral distribution Chest CT is remarkably considered as an imminent diagnostic tool and follow-up study in pulmonary changes in COVID-19 patients; being familiar to other coronavirus family CT findings, this improve our diagnostic experience and hence enhance our ability to early diagnose and combat the outbreak of COVID-19.
    keywords: chest; coronavirus; covid-19; imaging; patients
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        item: #164 of 7819
          id: cord-030984-2mqn4ihm
      author: Davies, Anna
       title: Riskscapes and the socio-spatial challenges of climate change
        date: 2020-08-20
       words: 8523
      flesch: 34
     summary: This is surprising, given the attention to climate change risks and their configuration by leading international agencies, including the Intergovernmental Panel on Climate Change (IPCC). Their research refines and sharpens our understanding of climate change risk and riskscapes, integrating understandings of risk from across diverse realms on inquiry under two, interlinked, themes: governance and institutional responses and vulnerabilities and inequalities.
    keywords: change; climate; climate change; communities; covid-19; global; governance; health; issue; müller; new; pandemic; resilience; risk; riskscapes; social
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        item: #165 of 7819
          id: cord-030992-ed0h045d
      author: Akhtar, Saeed
       title: Nutritional perspectives for the prevention and mitigation of COVID-19
        date: 2020-07-15
       words: 6854
      flesch: 27
     summary: 75, 76 Vitamin D Vitamin D receptors are present on monocytes, macrophages, T-and B-lymphocytes, and other immune cells. An ameliorative role of vitamin C supplementation in upper respiratory tract infections has been well described in numerous studies.
    keywords: cells; covid-19; function; immune; infections; iron; patients; role; selenium; supplementation; system; vitamin; zinc
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        item: #166 of 7819
          id: cord-030998-1u3fme80
      author: van Dalen, Hendrik P
       title: The COVID-19 Pandemic: Lessons for Financially Fragile and Aging Societies
        date: 2020-07-30
       words: 2935
      flesch: 46
     summary: The Gerontologist Gender differences in perceived workplace flexibility among older workers in the Netherlands: A brief report Blended work as a bridge between traditional workplace employment and retirement: A conceptual review Labor market reforms in Europe: Towards more flexicure labor markets Impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand COVID-19 and obesity The relationship between workplace stressors and mortality and health costs in the United States Reducing the health toll from US workplace stress Retirement savings adequacy in US defined contribution plans Worked to death: The relationships of job demands and job control with mortality Intergenerational risk sharing On the concept of health capital and the demand for health Prevalence of obesity and severe obesity among adults: United States Financial fragility in the US: Evidence and implications Does financial education impact financial literacy and financial behavior, and if so, when? The financial fragility of households and the rising proportion of people becoming obese calls for intensified efforts, both by individuals and employers to create financial buffers and keep on investing in health.
    keywords: buffers; covid-19; crisis; health; households; obesity; organizations; workers
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        item: #167 of 7819
          id: cord-031023-njs5d635
      author: Fadulelmola, Ahmed
       title: The impact of COVID-19 infection on hip fractures 30-day mortality
        date: 2020-08-27
       words: 2182
      flesch: 45
     summary: A recently published trial involving 6425 patients has shown that the immunosuppressant dexamethasone significantly reduced the death rate in COVID-19 positive patients, 21 supporting the theory of a hyperimmune reaction leading to higher mortality rates in COVID-19 patients. In our study, COVID-19 positive patients had higher mean leukocyte counts and lower mean lymphocytes count compared to COVID-19 negative patients.
    keywords: covid-19; hip; infection; mortality; patients
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        item: #168 of 7819
          id: cord-031035-yixlsymd
      author: Poom, Age
       title: COVID-19 is spatial: Ensuring that mobile Big Data is used for social good
        date: 2020-08-27
       words: 3921
      flesch: 39
     summary: The present trend in which corporate secrecy expands as the privacy of human beings contracts (Pasquale, 2015: 26) must be countered so that mobile data is used for social good rather than simply corporate profit. (2015) used mobile phone data to improve predictions on the spatial evolution of Haiti cholera epidemic, and Wesolowski et al.
    keywords: covid-19; crisis; data; et al; mobile; mobility; pandemic; use
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        item: #169 of 7819
          id: cord-031061-48xwfr9i
      author: Abdullah, Abdullah
       title: Innate Immune-mediated Antiviral Response to SARS-CoV-2 and Convalescent sera a potential Prophylactic and Therapeutic Agent to Tackle COVID-19
        date: 2020-08-16
       words: 2530
      flesch: 34
     summary: The current situation proclaim that passive immunization or passive antibody therapy is the best option for treatment and prevention of their immunoglobulin containing sera immediately (4, 5) . Although there are limited information on the innate immune responses to COVID-19, but increase in neutrophils (38%), reduction in lymphocytes (35%), increased serum interleukin-6 (52%) and increased C-reactive protein (84%) were also investigated in a study in Administration of antibodies to the susceptible individuals to a disease, for the purpose of prevention and treatment is called passive antibody therapy and the process is called passive immunization.
    keywords: antibody; convalescent; covid-19; immune; sars; sera
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        item: #170 of 7819
          id: cord-031081-szqrjxq2
      author: Campbell, Margaret C
       title: In Times of Trouble: A Framework for Understanding Consumers’ Responses to Threats
        date: 2020-07-09
       words: 11084
      flesch: 43
     summary: This framework is provided as a tool to help researchers structure their particular projects within the broader landscape of consumer threat response and to present some potential directions for future research. Given this opportunity for the Journal of Consumer Research to highlight some of what our field has to offer on the topic of consumer threat response, we elected to focus this issue around this important topic.
    keywords: consumers; covid-19; disruption; extent; family; health; home; impact; insecurity; issue; new; pandemic; potential; products; research; responses; self; term; threat
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        item: #171 of 7819
          id: cord-031100-ih1ci5cl
      author: Overby, Madison
       title: Calling for a United Action to defeat COVID-19
        date: 2020-08-06
       words: 1457
      flesch: 46
     summary: Oxford team begins vaccine trials in Brazil and South Africa to determine efficacy Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial An mRNA Vaccine against SARS-CoV-2 -Preliminary Report Remdesivir for 5 or 10 Days in Patients with Severe Covid-19 The case of Spain Impact of climate and public health interventions on the COVID-19 pandemic: a prospective cohort study International Public Health Responses to COVID-19 Outbreak: A Rapid Review COVID-19 and Italy: what next?
    keywords: covid-19; pandemic; policy; strategy
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        item: #172 of 7819
          id: cord-031101-6wb1g4dy
      author: Ramelli, Stefano
       title: Feverish Stock Price Reactions to COVID-19
        date: 2020-07-07
       words: 10994
      flesch: 54
     summary: of financial firms for the sake of consistency with the stock return results.) We start by providing evidence of heterogeneous impacts of COVID-19 on stock returns across industries.
    keywords: cash; china; covid-19; crisis; debt; fever; firms; january; leverage; march; market; outbreak; period; returns; stock; trade; u.s; value
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        item: #173 of 7819
          id: cord-031106-h1h5q9qo
      author: Schivardi, Fabiano
       title: Identifying the Real Effects of Zombie Lending
        date: 2020-07-07
       words: 7039
      flesch: 58
     summary: In fact, when we replace the share of zombie firms on the right-hand side of (3), Z jt , with an arguably exogenous supply side indicator of bank lending to zombie firms, we find no evidence that zombie lending hurts healthy firms. The danger of defining zombie firms solely on the basis of firm performance is recognized by Caballero et al. (2008) , who propose that a zombie is defined based on whether it receives subsidized financing.
    keywords: credit; crisis; distribution; firms; lending; performance; share; zombies
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        item: #174 of 7819
          id: cord-031112-fadju8a6
      author: Baker, Scott R
       title: The Unprecedented Stock Market Reaction to COVID-19
        date: 2020-07-18
       words: 5361
      flesch: 48
     summary: Looking back to 1985, we find no other infectious disease outbreak that had more than a tiny effect on U.S. stock market volatility. Following , we now take a mechanized approach to quantify the role of COVID-19 and other infectious diseases in U.S. stock market volatility.
    keywords: covid-19; daily; disease; emv; flu; market; pandemic; policy; stock; stock market; u.s; volatility
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        item: #175 of 7819
          id: cord-031143-a1qyadm6
      author: Pinto Neto, Osmar
       title: Compartmentalized mathematical model to predict future number of active cases and deaths of COVID-19
        date: 2020-08-30
       words: 5291
      flesch: 46
     summary: Lack of testing and under-notification of active cases has been largely reported for the COVID-19 (Hasell et al. 2020; WorldoMeter, 2020; UFPel, 2020) ; in consequence, active cases data were corrected by a factor. Our main findings were as follows: (a) our model was able to accurately fit the either deaths or active cases data of all countries tested independent of what stage of the epidemic they were using optimized coefficient values in agreement with recent reports; (b) when trying to fit both sets of data at the same time, fit was good for some countries, but not for all; (c) using our model, large ranges for each input, and (black circles for deaths and green circle for active cases).
    keywords: cases; covid-19; data; deaths; model; number; rate; results
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        item: #176 of 7819
          id: cord-031175-4dm4asen
      author: Joo, Jaehun
       title: Resolving the tension between full utilization of contact tracing app services and user stress as an effort to control the COVID-19 pandemic
        date: 2020-09-01
       words: 5972
      flesch: 41
     summary: Although contact tracing apps can be effective for controlling COVID-19, the app usage can be stressful for users. Some of the successful examples of contact tracing apps in usage are Self-quarantine Safety Protection App required for South Korean residents by its government and Health QR Code Apps (hereafter called Health Code) mandated by the Chinese government (CDSCHQ 2020a; Gan and Culver 2020) .
    keywords: appraisal; apps; challenge; code; contact; covid-19; health; information; study; users
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        item: #177 of 7819
          id: cord-031232-6cv8n2bf
      author: de Weck, Olivier
       title: Handling the COVID‐19 crisis: Toward an agile model‐based systems approach
        date: 2020-08-27
       words: 7909
      flesch: 45
     summary: In this paper, we draw attention to the core importance of having realistic system models to manage and to mitigate a systemic crisis of the order of magnitude such as the COVID-19 crisis. In this paper, authors from several of the key countries involved in COVID‐19 propose a holistic systems model that views the problem from a perspective of human society including the natural environment, human population, health system, and economic system.
    keywords: approach; confinement; covid-19; covid-19 crisis; crisis; epidemic; health; human; models; population; society; system; time
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        item: #178 of 7819
          id: cord-031378-iy67xnec
      author: Atif, Iqra
       title: The Role of Digital Technologies that Could Be Applied for Prescreening in the Mining Industry During the COVID-19 Pandemic
        date: 2020-09-03
       words: 4711
      flesch: 41
     summary: The National Academies of Sciences, Engineering and Medicine reported that ultraviolet (UV) light-based walkthrough gates possibly could eradicate the coronavirus that contains the deadly Fig. 9 IoT-Q-Band system for real-time monitoring of the health condition of individual and ensure social distancing to prevent the spread of COVID-19 virus, source: Singh et al. These devices have already been applied in COVID-19 conditions, not only to gather digital health data, but also to ensure that people obey certain lockdown and quarantine regulations.
    keywords: covid-19; face; fig; health; industry; mining; mining industry; pandemic; spread; system; workers
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        item: #179 of 7819
          id: cord-031417-y9g00712
      author: Ohme, Jakob
       title: Staying Informed and Bridging “Social Distance”: Smartphone News Use and Mobile Messaging Behaviors of Flemish Adults during the First Weeks of the COVID-19 Pandemic
        date: 2020-09-03
       words: 6893
      flesch: 45
     summary: We find evidence of this by looking at news app use on March 12, when the national security council announced the first lockdown restrictions, including the closure of bars, restaurants, and schools. 4 The increase in news app use during the same period is not visible for the day before and after March 12.
    keywords: apps; average; communication; covid-19; crisis; increase; information; mobile; news; people; smartphones; times; use
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        item: #180 of 7819
          id: cord-031418-ucdu4btq
      author: None
       title: Nervenschäden schon bei milden COVID-19-Verläufen?
        date: 2020-09-04
       words: 229
      flesch: 38
     summary: Auch hier gingen stationäre Aufnahme und schwerer Verlauf primär mit hohem Alter, einer progredienten MS sowie weiteren Begleiterkrankungen einher, nicht jedoch mit der Art der MS-Therapie. Association of neuronal injury blood marker neurofilament light chain with mild-to-moderate COVID-19 Headache and impaired consciousness level associated with SARS-CoV-2 in CSF: So werden die häufig auftretenden Geruchsstörungen eher einer Schädigung des Nasenepithels zugeschrieben, Schlaganfälle auf Koagulationsstörungen und Vaskulitiden.
    keywords: auf; covid-19; die
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        item: #181 of 7819
          id: cord-031460-nrxtfl3i
      author: Sharma, Vikas Kumar
       title: Modeling and Forecasting of COVID-19 Growth Curve in India
        date: 2020-09-05
       words: 6143
      flesch: 60
     summary: Since many real-life datasets consist of an element of non-stationarity, to model such datasets, ARIMA model was developed. ( , 2015 for more details on ARIMA model, estimation and its application.
    keywords: arima; cases; covid-19; data; exponential; growth; india; model; time; values
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        item: #182 of 7819
          id: cord-031461-r9lv43us
      author: Asad, Ali
       title: Evolution of COVID-19 Pandemic in India
        date: 2020-09-05
       words: 3974
      flesch: 64
     summary: by dynamical modeling Forecasting the novel coronavirus covid-19 Temporal dynamics of COVID-19 outbreak and future projections: a data-driven approach Unlocking towns and cities: COVID-19 exit strategy Assessment of 21 days lockdown effect in some states and overall India: a predictive mathematical study on COVID-19 outbreak Covid-19 predictions using a Gauss model Modeling and forecasting for COVID-19 growth curve in India Self-burnout -a (3) 270t − 14000 (±1.4%) (4) 13t 2 − 2700t + 15 × 10 4 (±0.45%) (1) 6.3e 0.19t (±9.7%) (March 21) (2) 4.7t 2 − 330t + 8300 (±1.6%) (2) 0.1t 3 − 9t 2 + 330t − 3900 (±4.8%)
    keywords: covid-19; curves; epidemic; states
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        item: #183 of 7819
          id: cord-031493-w8agvg9g
      author: Davido, Benjamin
       title: Possible therapies of Post-COVID-19 chronic symptoms()
        date: 2020-09-06
       words: 154
      flesch: 29
     summary: key: cord-031493-w8agvg9g authors: Davido, Benjamin; Seang, Sophie; Barizien, Nicolas; Tubiana, Roland; de Truchis, Pierre title: Possible therapies of Post-COVID-19 chronic symptoms() date: 2020-09-06 journal: Clin Microbiol Infect DOI: 10.1016/j.cmi.2020.09.001 sha: doc_id: 31493 cord_uid: w8agvg9g nan responsible for dysautonomia in patients with persistent symptoms following acute SARS-23 COV2 infection. Actually, we did not state that these symptoms of autonomic impairment do not require 28 specific treatment, but we believe it must be a case by case management depending on the breathing/hyperventilation syndrome in adults Efficacy of 68 Therapies for Postural Tachycardia Syndrome: A Systematic Review and Meta-69 analysis
    keywords: symptoms
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        item: #184 of 7819
          id: cord-031518-1w14wr0i
      author: Khodarahmi, Reza
       title: The ACE2 as a “rescue protein” or “suspect enzyme” in COVID-19: possible application of the “engineered inactive hrsACE2” as a safer therapeutic agent in the treatment of SARS-CoV-2 infection
        date: 2020-09-07
       words: 4657
      flesch: 41
     summary: [28] and higher serum ACE2 activity is correlated with increasing severity of heart failure [29] . In agreement with the latter observation, dramatic increase in ACE2 expression in the SARS-CoVinfected bronchial cells has been shown by bioinformatics analyses [53] .
    keywords: ace2; activity; angiotensin; cov-2; covid-19; heart; hypertension; infection; patients; sars
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        item: #185 of 7819
          id: cord-031534-agj3nnr8
      author: Calderón, José Lemus
       title: Differentiating characteristics of asthmatic patients in the SARS-CoV2 infection.
        date: 2020-09-07
       words: 295
      flesch: 36
     summary: Coronavirus Disease (COVID-19) Situation Reports Prevalence and characterization of asthma in hospitalized and non-hospitalized patients with COVID-19 Risk factors for severity and mortality in adult COVID-19 in patients in Wuhan Is asthma a risk factor for severe outcomes? Guía Española para el Manejo del Asma (GEMA) Año 2020 Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 Network.
    keywords: asthma; patients
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        item: #186 of 7819
          id: cord-031590-k16gsa7e
      author: Gharekhanloo, Farideh
       title: Variety of radiological findings in a family with COVID-19: a case report
        date: 2020-09-09
       words: 2629
      flesch: 50
     summary: However, lower lobe predominance in both cases was compatible with the lung involvement pattern of adult COVID-19. Furthermore, the absence of adenopathy, nodule cavitation, and pleural effusion was also in line with that reported for adult COVID-19.
    keywords: cases; chest; children; covid-19; patients
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        item: #187 of 7819
          id: cord-031700-xxku8q1f
      author: Hess, Kristy
       title: Local newspapers and coronavirus: conceptualising connections, comparisons and cures
        date: 2020-09-09
       words: 7614
      flesch: 36
     summary: We have adopted social capital theory more broadly to focus on the role and power of local news media to connect people with each other, a practice that builds a local journalist and newspaper's legitimacy while also enhancing community social capital, identity and progress (Hess, 2014) . At a time when local news media profits have slumped, the company recorded a 10 per cent increase for the first quarter of 2020 and a rise in the number of users (Horwitz, 2020) -a point we shall return to soon.
    keywords: australia; covid-19; crisis; digital; facebook; future; government; journalism; media; news; newspapers; pandemic; power; public; regional; social
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        item: #188 of 7819
          id: cord-031726-ubt9wnf9
      author: Ad’hiah, Ali H.
       title: Evaluating of the association between ABO blood groups and coronavirus disease 2019 (COVID-19) in Iraqi patients
        date: 2020-09-11
       words: 2560
      flesch: 52
     summary: key: cord-031726-ubt9wnf9 authors: Ad’hiah, Ali H.; Allami, Risala H.; Mohsin, Raghdan H.; Abdullah, Maha H.; AL-Sa’ady, Ali J. R.; Alsudani, Mustafa Y. title: Evaluating of the association between ABO blood groups and coronavirus disease 2019 (COVID-19) in Iraqi patients date: 2020-09-11 journal: Egypt J Med Hum Genet DOI: 10.1186/s43042-020-00097-x sha: doc_id: 31726 cord_uid: ubt9wnf9 BACKGROUND: Susceptibility to the pandemic coronavirus disease 2019 (COVID-19) has recently been associated with ABO blood groups in patients of different ethnicities. ABO blood groups were determined in 300 hospitalized COVID-19 Iraqi patients (159 under therapy, 104 recovered, and 37 deceased) and 595 healthy blood donors.
    keywords: abo; cases; covid-19; group
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        item: #189 of 7819
          id: cord-031739-4hapxw7l
      author: Mohamed, Yahye Garad
       title: Clinical and chest CT presentations from 27 patients with COVID-19 pneumonia in Mogadishu, Somalia: a descriptive study
        date: 2020-09-11
       words: 2085
      flesch: 47
     summary: In this article, we aimed to demonstrate the clinical and radiological characteristics of COVID-19 patients in Somalia from 20 March 2020 to 20 April 2020. Fever, cough, shortness of breath (SOB), fatigue, and myalgia were the common clinical manifestations of COVID-19 patients [5] .
    keywords: chest; covid-19; patients; study
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        item: #190 of 7819
          id: cord-031818-lawd185l
      author: Rich, Robert Soler
       title: Expanded mesenchymal stem cells: a novel therapeutic approach for SARS-CoV-2 pneumonia (COVID-19). Concepts regarding a first case()
        date: 2020-09-12
       words: 974
      flesch: 33
     summary: Given that our research team has extensive experience in cell therapy, on 2nd April, with prior authorization and under the control of the Spanish Agency of Medicines and Medical Devices, we infused intravenously a dose of 80 x 10 E6MSC of allogeneic bone marrow (1 x 10 E6MSC/kg of weight) in suspension of 100 cc saline solution administered at a rate of 40 drops/min. Due to the interest generated, it is considered appropriate to disclose the concept, the foundations and the procedure of this innovative therapy in the experimental phase, reporting the experience of what we consider to be the first case of COVID-19 treated in our country using intravenous mesenchymal stem cell therapy.
    keywords: cells; covid-19; sars; therapy
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        item: #191 of 7819
          id: cord-031835-jx8lzdl8
      author: Zhao, Fei
       title: Time to lead the prevention and control of public health emergencies by informatics technologies in an information era
        date: 2020-09-14
       words: 960
      flesch: 42
     summary: Thereafter, we have witnessed the exponential growth of COVID-19 cases globally over the past few months (Fig. 1 ). The growth of COVID-19 cases globally from Data on COVID-19 by Our World in Data COVID-19 map Jvion.
    keywords: covid-19; data; epidemic; health
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        item: #192 of 7819
          id: cord-031840-k9l91unc
      author: Lu, Li
       title: Forum: COVID-19 Dispatches
        date: 2020-09-11
       words: 15690
      flesch: 50
     summary: Viruses are viruses are viruses. With the similar control of cases less than 20,000, Japan and South Korea remain at the heart of this imagined safe zone in company with China even though the reality has seen even fewer confirmed cases in other parts of Asia as well as the recent resurgence of virus spreading in all these three countries.
    keywords: china; chinese; coronavirus; countries; covid-19; crisis; earth; east; health; history; humans; india; japan; korea; life; media; national; new; normal; pandemic; people; public; south; state; time; viruses; world
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        item: #193 of 7819
          id: cord-031885-by4cujyy
      author: Guo, Hai
       title: The digitalization and public crisis responses of small and medium enterprises: Implications from a COVID-19 survey
        date: 2020-09-15
       words: 7547
      flesch: 36
     summary: Based on data from an online questionnaire survey conducted with 518 Chinese SMEs, the present study explores the relationships among digitalization, crisis response strategies to the COVID-19 outbreak, and the crisis response performance of SMEs. The results show that the digitalization of SMEs is positively associated with the implementation of crisis response strategies and performance, and that crisis response strategies are also positively associated with performance.
    keywords: business; capabilities; crisis; digitalization; et al; firms; performance; responses; smes; strategies; term
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        item: #194 of 7819
          id: cord-031938-oe5gf257
      author: Tor, Phern-Chern
       title: Model for ethical triaging of electroconvulsive therapy patients during the COVID-19 pandemic
        date: 2020-08-19
       words: 2277
      flesch: 34
     summary: key: cord-031938-oe5gf257 authors: Tor, Phern-Chern; Tan, Jacinta; Loo, Colleen title: Model for ethical triaging of electroconvulsive therapy patients during the COVID-19 pandemic date: 2020-08-19 journal: nan DOI: 10.1192/bjb.2020.99 sha: doc_id: 31938 cord_uid: oe5gf257 Electroconvulsive therapy (ECT) is an essential treatment for severe mental illnesses such as depression with suicidality and catatonia. Using the proposed ethical framework below, the patient's youth and catatonia would satisfy the principles of 'maximising benefits' and 'giving priority to the worst off', but it would be contrary to the principle of 'promoting and rewarding instrumental value', as treating the patient would expose the ECT team and other patients to a significant risk of getting COVID-19, especially if the ECT unit is not fully prepared to deal with suspected or positive COVID-19 patients.
    keywords: covid-19; ect; patients; risk; treatment
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        item: #195 of 7819
          id: cord-031940-bbord079
      author: Ye, Tingqing
       title: Analysis and prediction of confirmed COVID-19 cases in China with uncertain time series
        date: 2020-09-16
       words: 3910
      flesch: 60
     summary: Fuzzy Optimization and Decision Making Least-squares estimation for uncertain moving average model Least absolute deviations estimation for uncertain autoregressive model Uncertain regression analysis: An approach for imprecise observations Uncertain hypothesis test with application to uncertain regression analysis Multivariate uncertain regression model with imprecise observations Least absolute deviations for uncertain multivariate regression model Analytic solution of uncertain autoregressive model based on principle of least squares Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Tukeys biweight estimation for uncertain regression model with imprecise observations Uncertain revised regression analysis with responses of logarithmic, square root and reciprocal transformations Uncertain Gompertz regression model with imprecise observations Residual and confidence interval for uncertain regression model with imprecise observations Uncertain maximum likelihood estimation with application to uncertain regression analysis Uncertain growth model for the cumulative number of COVID-19 infections in China.
    keywords: analysis; model; series; time
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        item: #196 of 7819
          id: cord-031942-mfz313q0
      author: Kim, Hye Kyung
       title: Effects of COVID-19 Misinformation on Information Seeking, Avoidance, and Processing: A Multicountry Comparative Study
        date: 2020-09-13
       words: 7774
      flesch: 30
     summary: Prior theorizing on risk communication has often focused on immediate outcomes of information exposure; yet there is a lack of understanding about the subsequent information management that follows exposure to risk information (So et al., 2019) . The online survey results showed that misinformation exposure reduced information insufficiency, which subsequently led to greater information avoidance and heuristic processing, as well as less systematic processing of COVID-19 information.
    keywords: avoidance; covid-19; exposure; information; insufficiency; misinformation; processing; risk; sample; seeking
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        item: #197 of 7819
          id: cord-031984-kcs6oukj
      author: Gupta, Amitesh
       title: Estimating the Impact of Daily Weather on the Temporal Pattern of COVID-19 Outbreak in India
        date: 2020-09-17
       words: 5021
      flesch: 37
     summary: Here, growth rate between March 01 and June 04, 2020 for the overall country and for each selected city was calculated using following formula: Here, NF refers to the number of COVID-19 cases recorded on the 1st day of record,NE refers to the number of COVID-19 cases recorded on the last day of the study period (June 04, 2020), and n refers to the number of days between the first day of COVID-19 case detection and the last day of the study period. The data of daily COVID-19 cases were collected from the official website of the Ministry of Health of India (https ://www.
    keywords: cases; cities; covid-19; daily; days; et al; india; temperature; transmission; weather
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        item: #198 of 7819
          id: cord-032073-8eguv697
      author: El Fakiri, K.
       title: Epidemiology and Clinical Features of Coronavirus Disease 2019 in Moroccan Children
        date: 2020-07-12
       words: 1517
      flesch: 52
     summary: All confirmed COVID-19 cases <18 years were included except from newborns. COVID-19 pediatric cases were defined as follows: Possible case: when a history of contact with a confirmed case of SARS-COV-2, and/or an acute respiratory infection of unknown etiology are present; and confirmation of infection was obtained from all patients at admission by detection of SARS-COV-2 nucleic acid on nasopharyngeal swab specimens using RT-PCR.
    keywords: cases; children; covid-19; days
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        item: #199 of 7819
          id: cord-032222-i6gfp4me
      author: Xue, Ling
       title: A quick look at the latest developments in the COVID-19 pandemic
        date: 2020-09-10
       words: 2885
      flesch: 41
     summary: Use of convalescent plasma therapy in SARS patients in Hong Kong Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection Meta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment? Treatment with convalescent plasma for influenza A (H5N1) infection GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV First case of 2019 novel coronavirus in the United States Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial Baricitinib as potential treatment for 2019-nCoV acute respiratory disease Potential impact of seasonal forcing on a SARS-CoV-2 pandemic Preliminary studies have suggested that the pathogenic mechanism of SARS-CoV-2 is similar to that of SARS-CoV. Both viruses bind to the cell surface receptor angiotensin converting enzyme 2 (ACE2) in human airway epithelial cells via the S protein on the envelope and enter the host cell.
    keywords: coronavirus; cov-2; covid-19; infection; novel; patients; sars; transmission
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        item: #200 of 7819
          id: cord-032227-xxa0hlpu
      author: Pyszczynski, Tom
       title: Terror Management Theory and the COVID-19 Pandemic
        date: 2020-09-17
       words: 5077
      flesch: 35
     summary: Increased death awareness associated with the threat of COVID-19 is difficult to successfully manage because COVID-19 has undermined access to many aspects of people's anxiety buffers; compromised anxiety buffers leave people vulnerable to experiencing higher levels of death anxiety than usual. TMT posits that people manage death anxiety with two distinct systems, referred to as proximal and distal defenses (Pyszczynski et al., 1999) .
    keywords: anxiety; covid-19; death; defenses; pandemic; people; terror; virus
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        item: #201 of 7819
          id: cord-032231-7pwy8cyq
      author: Cho, Sang-Wook (Stanley)
       title: Quantifying the impact of nonpharmaceutical interventions during the COVID-19 outbreak: The case of Sweden
        date: 2020-08-29
       words: 7523
      flesch: 48
     summary: One hundred days after the infection case per one million population exceeds one, I find that the infection case in synthetic Sweden is around 75 percent lower than that of actual Sweden, which implies that stricter containment measures are associated with limiting the spread of the COVID-19 infection. Consistent with BDM, I also find that during the first 5 weeks, the infection rate in synthetic Sweden was not significantly lower than that in actual Sweden.
    keywords: cases; countries; covid-19; effect; infection; lockdown; measures; policy; sweden; synthetic; time; treatment
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        item: #202 of 7819
          id: cord-032239-uoy0ywvw
      author: Scotto di Uccio, Fortunato
       title: ANMCO POSITION PAPER: Network Organization for the Treatment of Acute Coronary Syndrome Patients during the Emergency COVID-19 Pandemic
        date: 2020-08-27
       words: 2404
      flesch: 31
     summary: The regional STEMI-NSTEMI network for the management and treatment of COVID-19 or suspect COVID-19 patients should be characterized by the existence of at least 1 HUB-COVID Center with the following features: • Two cath labs, one exclusively for COVID-19 or suspect COVID-19 patients; • A dedicated zone and an intensive care unit (not necessarily cardiologic) for the isolation and treatment of COVID-19 or suspect COVID-19 patients and in network with a COVID Unit. If the HUB-COVID Center is not available for COVID-19 or suspect COVID-19 patients, the Spoke Center must alert the catheter room of a HUB-NO COVID Center.
    keywords: case; center; covid-19; patients; risk; stemi
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        item: #203 of 7819
          id: cord-032240-xswtx940
      author: Sauer, François
       title: Pericardial effusion in patients with COVID-19: case series
        date: 2020-09-09
       words: 2245
      flesch: 47
     summary: • A systematic screening for PE should be performed in COVID-19 patients either via a chest computed tomography scan in case of respiratory symptoms, or via transthoracic echocardiography in case of chest pain, haemodynamic instability, or respiratory worsening. Case 3 was a cardiac tamponade due to COVID-19 pericarditis, with a positive polymerase chain reaction on pericardial fluid.
    keywords: cardiac; covid-19; day; patient
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        item: #204 of 7819
          id: cord-032244-s7t5u9lf
      author: Valente, Serafina
       title: ANMCO POSITION PAPER: Considerations on in-hospital cardiological consultations and cardiology outpatient clinics during the COVID-19 pandemic
        date: 2020-08-27
       words: 1513
      flesch: 26
     summary: The reasons underlying the importance of COVID-19 infection for cardiologists are as follows: • It is a pandemic that affects everyone, especially cardiovascular patients, as shown by Chinese cases 2-6 ; • COVID-19 patients may have cardiovascular complications, although they are not so frequent 7, 8 ; • Cardiovascular disease continues to be prevalent in the general population and patients with acute coronary syndrome may at the same time be positive for COVID-19. The aim of this document is to propose algorithms for the management of cardiovascular diseases during COVID-19 emergency with the objective of providing patients with optimal care, minimizing contagion risk and appropriately managing personal protective equipment.
    keywords: covid-19; disease; emergency; patients; risk
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        item: #205 of 7819
          id: cord-032245-f5g3r3nv
      author: Bahri, Amrita
       title: Women at the frontline of COVID-19: Can Gender Mainstreaming in Free Trade Agreements Help?
        date: 2020-09-10
       words: 7542
      flesch: 47
     summary: against women Women professionals tend to take a bigger chunk of domestic responsibilities as compared to men even during their working hours. The discussion brings to light a number of ways in which the existing FTAs can help connect more women to the economy in the post-COVID-19 world.
    keywords: access; agreements; countries; covid-19; economy; employment; ftas; gender; health; pandemic; trade; women; world
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        item: #206 of 7819
          id: cord-032256-7yrh16ab
      author: Susskind, Daniel
       title: The economics of the COVID-19 pandemic: an assessment
        date: 2020-08-29
       words: 6485
      flesch: 54
     summary: He argues that the choice of numbers used to represent the 'value of lives saved' from COVID-19 interventions, more than likely, substantially understate the social benefits. Optimal Targeted Lockdowns in a Multi-Group SIR Model After the Lockdown: Macroeconomic Adjustment to the COVID-19 Pandemic in Sub-Saharan Africa The Initial Impact of COVID-19 and Policy Responses on Household Incomes International Cooperation During the COVID-19 Pandemic Relationship Between Clinical Signs and Transmission of an Infectious Disease and the Implications for Control A Workable Strategy for COVID-19 Testing: Stratified Periodic Testing rather than Universal Random Testing Reforming the UK Financial System to Promote Regional Development in Post-COVID Britain
    keywords: countries; covid-19; crisis; disease; instance; interventions; issue; pandemic; policy; world
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        item: #207 of 7819
          id: cord-032268-oj94e8wo
      author: Kaeuffer, Charlotte
       title: The BAS²IC score: a useful tool to identify patients at high risk of early progression to severe COVID-19
        date: 2020-09-01
       words: 1628
      flesch: 46
     summary: Rapid identification of patients at a high risk of developing severe COVID-19 appeared to be crucial to help clinicians closely monitor such patients and for triage. On the contrary, those with score >14 were considered to have a high risk, requiring rapid implementation of appropriate measures, such as hospitalization and consideration of specific therapeutics (e.g. dexamethasone, remdesivir)
    keywords: covid-19; patients; risk; score
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        item: #208 of 7819
          id: cord-032276-bvbz94bi
      author: Azam, Gaousul
       title: Letter: Outpatient Consultation and Silent Transmission of COVID-19: Risk for the Neurosurgeon?
        date: 2020-09-05
       words: 918
      flesch: 34
     summary: 9 Symptom screening, thermal scanning, and taking recent history of contact with COVID-19 patients are essential, but when community transmission occurs, it is very difficult to assume the actual number of asymptomatic patients without testing. 8 COVID-19 also spreads through air, which might play an important role in COVID-19 infection during outpatient management.
    keywords: asymptomatic; covid-19; patients
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        item: #209 of 7819
          id: cord-032285-gkd1wb09
      author: Collier, Paul
       title: Reforming the UK financial system to promote regional development in post-COVID Britain
        date: 2020-08-29
       words: 5121
      flesch: 43
     summary: The spatial distribution of venture capital finance has been highly skewed to the south-east, which, in the most recent 3 years for which data are available, has received between 61 and 77 per cent of it (Mason, 2020) . Both the staff of SME venture capital firms, and the Impact-Investing wealth-holders who back them, are typically motivated both by an intrinsic purpose to address social problems and the extrinsic financial benefit they derive from successful selection of SMEs: public and private purposes, while not coincident, are not incompatible.
    keywords: capital; covid; finance; firms; investment; opportunities; smes; uncertainty; venture
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        item: #210 of 7819
          id: cord-032332-bfggtolv
      author: Liu, Zhe
       title: Uncertain growth model for the cumulative number of COVID-19 infections in China
        date: 2020-09-19
       words: 2909
      flesch: 51
     summary: key: cord-032332-bfggtolv authors: Liu, Zhe title: Uncertain growth model for the cumulative number of COVID-19 infections in China date: 2020-09-19 journal: To better describe this pandemic automatically, this paper first employs uncertain growth models with the help of uncertain hypothesis tests to detect and modify outliers in data.
    keywords: covid-19; growth; model; uncertain
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        item: #211 of 7819
          id: cord-032383-2dqpxumn
      author: Shuja, Junaid
       title: COVID-19 open source data sets: a comprehensive survey
        date: 2020-09-21
       words: 16209
      flesch: 51
     summary: CNNs and deep learning techniques are reported to overfit models due to the limited size of COVID-19 data sets [49] . Most of the studies that estimate COVID-19 transmissions utilize COVID-19 case data collected from various governmental, journalistic, and academic sources [42] .
    keywords: analysis; application; authors; cases; cough; covid-19; covid-19 cases; covid-19 diagnosis; data; data sets; diagnosis; images; learning; mobility; model; pandemic; ray; research; set; source; source data; study; techniques
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        item: #212 of 7819
          id: cord-032450-mklmsw01
      author: Yasin, Rabab
       title: Chest X-ray findings monitoring COVID-19 disease course and severity
        date: 2020-09-22
       words: 5362
      flesch: 59
     summary: It had been reported by Jacobi et al. of large pulmonary nodule in COVID-19 patient [26] . On the 5th day (c), 8th day (d), and 12th day (e), air space consolidation opacities (arrows) were almost the same but with increased reticular interstitial thickening seen on d and e World Health Organization website Understanding of COVID-19 based on current evidence World Health Organization (2020) WHO Director-General's remarks at the media briefing on Anti-Chinese sentiment during the 2019-nCoV outbreak Fong AH-T et al Frequency and distribution of chest radiographic findings in COVID-19 positive patients Imaging profile of the COVID-19 infection: radiologic findings and literature review The first case of 2019 novel coronavirus pneumonia imported into Korea from Wuhan, China: implication for infection prevention and control measures Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan Radiographic severity index in COVID-19 pneumonia: relationship to age and sex in 783 Italian patients Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection Imaging of pulmonary viral pneumonia ACR recommendations for the use of chest radiography and computed tomography (CT) for suspected COVID-19 infection Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT Emerging 2019 novel coronavirus (2019-nCoV) pneumonia Finkelstein M et al Clinical and chest radiography features determine patient outcomes in young and middle age adults with COVID-19 CT imaging features of 2019 novel coronavirus (2019-nCoV) Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Fleischner Socity: Glossary of terms for thoracic imaging Coronavirus disease 2019 (COVID-19): a systematic review of imaging findings in 919 patients Portable chest X-ray in coronavirus disease-19 (COVID-19): a pictorial review Chest CT findings in 2019 novel coronavirus (2019-nCoV) infections from Wuhan, China: key points for the radiologist.
    keywords: chest; lung; patients; ray; score; severity
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        item: #213 of 7819
          id: cord-032552-rjuug7er
      author: Umviligihozo, Gisele
       title: Sub-Saharan Africa preparedness and response to the COVID-19 pandemic: A perspective of early career African scientists
        date: 2020-07-08
       words: 5931
      flesch: 38
     summary: However, a comparison of the early phases of the pandemic in some African and European countries has shown a positive impact of early interventions initiated by SSA countries resulting in distinct disease trajectories, For example a comparison of the infection dynamics in the United States, United Kingdom, Italy and Spain vs South Africa and Cameroon has shown a continual exponential peak in non-African countries but slow and gradual increase in both of the SSA countries 85 . There, consistent with the recent study by M. Njenga et al 3 which investigated the causes of low morbidity and low mortality of COVID-19 in African countries, we also suggest that other factors such as a warm climate, young population, pre-existing cross-reactive immunity may have considerably contributed to the evolution of the COVID-19 pandemic in SSA countries.
    keywords: african; countries; cov-2; covid-19; health; interventions; pandemic; response; sars; ssa; ssa countries
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        item: #214 of 7819
          id: cord-032599-b4lcqzcv
      author: Doumbia-Henry, Cleopatra
       title: Shipping and COVID-19: protecting seafarers as frontline workers
        date: 2020-09-24
       words: 4925
      flesch: 42
     summary: They address the roles of shipping companies, agents and representatives, including crewing agencies and seafarers, and cover seaports, airports and airlines involved in travel operations for ship crew changes. Circular Letter No.4204/Add.12 (27 April 2020) Coronavirus Joint statement IMO-UNCTAD -Call for collaborative action in support of keeping ships moving, ports open and cross-border trade flowing during the COVID-19 pandemic Coronavirus (COVID-19) -Accelerating digitalization of maritime trade and logistics -A call to action Coronavirus (COVID-19) -Guidance for flag States regarding surveys and renewals of certificates during the COVID-19 pandemic Joint Statement IMO-ICAO-ILO on designation of seafarers, marine personnel, fishing vessel personnel, offshore energy sector personnel, aviation personnel, air cargo supply chain personnel and service provider personnel at airports and ports as key workers ) -Coronavirus (COVID 19) -Preparing for post COVID-19 operations: considerations and practicalities for port community systems, single window and other electronic exchange platforms ) -Coronavirus (COVID 19) -COVID-19 related guidelines for ensuring a safe shipboard interface between ship and shore-based personnel ) -Coronavirus (COVID 19) -Personal protective equipment ) -Coronavirus (COVID-19) -Recommended framework of protocols for ensuring safe ship crew changes and travel during the coronavirus (COVID-19) pandemic Coronavirus (COVID-19) -Recommendations for Governments and relevant national authorities on Global governance and COVID-19:
    keywords: covid-19; crew; global; imo; industry; maritime; pandemic; personnel; seafarers
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        item: #215 of 7819
          id: cord-032691-d9jg0471
      author: Carrillo-Larco, Rodrigo M.
       title: COVID-19 and Guillain-Barre Syndrome: a systematic review of case reports
        date: 2020-09-21
       words: 2715
      flesch: 52
     summary: Comparison with GBS patients in the context of another viral outbreak (Zika), revealed similarities and differences that deserves further scrutiny and epidemiological studies. In all but one patient, COVID-19 was diagnosed with molecular tests; one patient had the diagnosis made with serological tests ( Among GBS patients, 6 debuted with ascendant weakness and 3 with facial weakness (Table 1 ); in addition, 7 patients evolved to respiratory failure between 4 and 6 days after GBS onset (Table 1) .
    keywords: case; covid-19; data; gbs; patients; reports
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        item: #216 of 7819
          id: cord-032692-h2c7ogga
      author: Northstone, Kate
       title: The Avon Longitudinal Study of Parents and Children - A resource for COVID-19 research: Questionnaire data capture May-July 2020
        date: 2020-09-22
       words: 5331
      flesch: 51
     summary: The update to the original dataset obtained from our first online questionnaire 6 is described here, together with any variables that have been derived using both sets of questionnaire data. The second generation of The Avon Longitudinal Study of Parents and Children (ALSPAC-G2): a cohort profile The Avon Longitudinal Study of Parents and Children - A resource for COVID-19 research: Questionnaire data capture Publisher Full Text Research electronic data capture (REDCap) -A metadata-driven methodology and workflow process for providing translational research informatics support PubMed Abstract | Publisher Full Text | Free Full Text The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking.
    keywords: alspac; children; covid-19; data; health; participants; questionnaire; second; study
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        item: #217 of 7819
          id: cord-032751-pmclolvh
      author: Head, Katharine J.
       title: A National Survey Assessing SARS-CoV-2 Vaccination Intentions: Implications for Future Public Health Communication Efforts
        date: 2020-09-23
       words: 5100
      flesch: 38
     summary: Of note for communication scholars, these findings suggest that social normative messaging could capitalize on the high level of vaccine intention. Importantly, because vaccine intent and/or need may be different for people who were previously infected with SARS-CoV-2 and perceived threat variables (discussed below) are usually only measured for future threats, only participants who answered no to the question do you believe that you've had COVID-19 are included in the current study (n = 3,159).
    keywords: covid-19; health; intentions; participants; ref; sars; vaccination; vaccine; variables
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        item: #218 of 7819
          id: cord-032757-4nqg9m74
      author: Zhan, Bingyan
       title: Radiographic characteristics and early clinical manifestations of family clustered coronavirus disease 2019 (COVID-19)
        date: 2020-08-17
       words: 2148
      flesch: 59
     summary: This study enrolled confirmed COVID-19 patients from different regions. No antibodies to other viruses were detected in female patients with no epidemiological history of exposure.
    keywords: chest; covid-19; patients
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        item: #219 of 7819
          id: cord-032820-l0vkq0j3
      author: Mohamed, Sherif
       title: Incidence and pathophysiologic mechanisms of stroke in the COVID-19 pandemic: the dilemma
        date: 2020-09-29
       words: 1626
      flesch: 49
     summary: WHO coronavirus disease (COVID-19) dashboard Neurologic manifestations of hospitalized patients with coronavirus disease Risk of ischemic stroke in patients with coronavirus disease 2019 (COVID-19) vs patients with influenza EXPRESS: COVID-19 and stroke-a global World Stroke Organization perspective The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients SARS-CoV-2 and stroke in a New York Healthcare System The baffling case of ischemic stroke disappearance from the casualty department in the COVID-19 era Anticytokine agents targeting interleukin signaling pathways for the treatment of atherothrombosis Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis Cerebrovascular disease is associated with an increased disease severity in patients with coronavirus disease 2019 (COVID-19): a pooled analysis of published literature Large-vessel stroke as a presenting feature of Covid-19 in the young Management of acute ischemic stroke in patients with COVID-19 infection: insights from an international panel On being a neurologist in Italy at the time of the COVID-19 outbreak Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Not applicable Availability of data and materials Not applicable Ethics approval and consent to participate Not applicable. The COVID-19 pandemic has, in different ways, negative impacts on care of stroke patients worldwide, and still, many challenges are faced by neurologists to improve care of stroke patients during such crisis.
    keywords: covid-19; pandemic; patients; stroke
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        item: #220 of 7819
          id: cord-032891-pvijxcgi
      author: Zhang, Joe
       title: Veno-venous Extracorporeal Membrane Oxygenation in Coronavirus Disease 2019: A Case Series
        date: 2020-09-25
       words: 2585
      flesch: 33
     summary: We aim to report clinical characteristics, management, and outcomes of COVID-19 patients requiring VV-ECMO, admitted over 2 months to a high-volume UK centre. In COVID-19 patients with severe respiratory failure, early consultation with an ECMO centre and joint decision-making on suitable support modality is a key strategy.
    keywords: covid-19; ecmo; extracorporeal; failure; membrane; oxygenation; patients
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        item: #221 of 7819
          id: cord-032928-m0awip9y
      author: Sobh, Eman
       title: Novel coronavirus disease 2019 (COVID-19) non-respiratory involvement
        date: 2020-10-01
       words: 4025
      flesch: 38
     summary: Zhonghua bing li xue za zhi= Pathological findings in the testes of COVID-19 patients: clinical implications SARS-CoV-2 and the testis: similarity with other viruses and routes of infection The need for urogenital tract monitoring in COVID-19 Orchitis: a complication of severe acute respiratory syndrome (SARS) Cytokines and the immune-testicular axis Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China COVID-19 and anosmia: a review based on up-to-date knowledge Human coronaviruses: respiratory pathogens revisited as infectious neuroinvasive, neurotropic, and neurovirulent agents Middle East respiratory syndrome National Health Commission of the People's Republic of China. Several studies reported acute kidney injury (AKI) in COVID-19 patients with variable incidence rate [24, 26, 32, 34, 35] .
    keywords: coronavirus; cov-2; covid-19; disease; infection; injury; kidney; manifestations; patients; sars; symptoms
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        item: #222 of 7819
          id: cord-032929-hqfzlddn
      author: Ciftci, Bahadir
       title: May regional anesthesia be a better choice for the COVID-19 pandemic?
        date: 2020-10-01
       words: 855
      flesch: 46
     summary: In summary, regional anesthesia techniques may be safer for both anesthesiologists and 2019-nCoV patients, if the required precautions are taken. key: cord-032929-hqfzlddn authors: Ciftci, Bahadir; Ekinci, Mursel; Atalay, Yunus Oktay title: May regional anesthesia be a better choice for the COVID-19 pandemic? date: 2020-10-01 journal:
    keywords: anesthesia; covid-19; regional
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        item: #223 of 7819
          id: cord-032972-nf5qwcj8
      author: van Osch, Dirk
       title: Takotsubo cardiomyopathy in COVID-19: a case report. Haemodynamic and therapeutic considerations
        date: 2020-08-27
       words: 1982
      flesch: 32
     summary: Frequent ECG monitoring of COVID-19 patients therefore is of paramount importance and timely echocardiography should be obtained when ECG abnormalities or haemodynamical problems occur. It is important that caregivers of COVID-19 patients are aware of the possible cardiovascular complications that coexist with this disease.
    keywords: cardiomyopathy; covid-19; lead; patients; takotsubo
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        item: #224 of 7819
          id: cord-033196-e2cejj95
      author: Smart, Neil
       title: Colorectal Surgery in the time of Covid 19
        date: 2020-09-23
       words: 913
      flesch: 49
     summary: Exactly how such challenges are met will depend upon the vagaries of health services in individual nations and the inevitable complexity of local in-hospital factors that exist purely to spite common sense and frustrate clinicians. Set against this backdrop, patients with colorectal conditions both benign and malignant continue to have health needs that must be met in a timely fashion or they face becoming collateral damage in health systems that were never designed to function on a crisis setting for longer than a few months.
    keywords: colorectal; covid; health
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        item: #225 of 7819
          id: cord-033204-v17d98c9
      author: Yen, Wei‐Ting
       title: Taiwan’s COVID‐19 Management: Developmental State, Digital Governance, and State‐Society Synergy
        date: 2020-09-23
       words: 6585
      flesch: 50
     summary: Originally, the chief commander was the Director-General of Taiwan's CDC, but soon after China locked down Wuhan on January 23rd, the Minister of Ministry of Health and Welfare (MOHW), the superior unit of Taiwan CDC, became the new chief commander of CECC. Taiwan CDC Inside Taiwan's new digital democracy Coronavirus: Taiwan making progress in getting illegal migrant workers to come forward.
    keywords: china; covid-19; crisis; disease; governance; government; health; mask; policy; production; response; sars; society; taiwan
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        item: #226 of 7819
          id: cord-033218-wpe0sl43
      author: Porsse, Alexandre A.
       title: The economic impacts of COVID‐19 in Brazil based on an interregional CGE approach
        date: 2020-09-21
       words: 4657
      flesch: 42
     summary: CGE models are a useful tool to simulate economic scenarios, since they incorporate a detailed set of behavioral economic equations, forming a system that recognizes the interdependence of transactional relationships between different economic agents: firms, families, government, and the external sector. These studies have pointed many transmission channels and economic effects.
    keywords: covid-19; effects; gdp; model; months; outbreak; reduction; results; scenario; shutdown
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        item: #227 of 7819
          id: cord-033287-24zkbi3z
      author: Ali, Sana
       title: Combatting Against Covid-19 & Misinformation: A Systematic Review
        date: 2020-10-07
       words: 5789
      flesch: 33
     summary: Jayaseelan et al. (2020) investigated the impacts of Social Media based misinformation on audience behavior during Covid19. Figure2 below provides a graphical representation of misinformation sources, types, and potential impacts.
    keywords: covid-19; health; healthcare; impacts; media; misinformation; news; pandemic; platforms; researchers; social
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        item: #228 of 7819
          id: cord-033312-ja45g4b0
      author: Yetkin, Ertan
       title: COVID-19 pandemic: a glimpse into newly diagnosed hypertensive patients
        date: 2020-09-17
       words: 632
      flesch: 14
     summary: Beyond its alarming mortality rate and easily transmissible nature through air droplets, it has also resulted in significant challenges in the cardiovascular area not only due to its higher mortality rates in cardiovascular disease and certain associated conditions, including diabetes mellitus and hypertension, but also due to the theoretically facilitated inoculation of lung tissue by the culprit agent, SARS-CoV-2 in these conditions [1, 2] . Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Hypertension and diabetes mellitus in patients with COVID 19 Receptor recognition by novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS Coronavirus disease 2019 (COVID-19) infection and Renin Angiotensin system blockers Effect of Renin-Angiotensin system blockage in patients with acute respiratory distress syndrome: a retrospective case control study Angiotensinconverting enzyme 2 protects from severe acute lung failure There are no conflicts of interest.
    keywords: arbs; covid-19
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        item: #229 of 7819
          id: cord-033329-gi0mug1p
      author: Montesi, Michela
       title: Understanding fake news during the Covid-19 health crisis from the perspective of information behaviour: The case of Spain
        date: 2020-10-06
       words: 8282
      flesch: 34
     summary: Although it tends to be predominant in politics, health fake news is also common (Montero-Liberona and Halpern, 2019) and it was expected that, in the Covid-19 crisis, it was being widely disseminated. key: cord-033329-gi0mug1p authors: Montesi, Michela title: Understanding fake news during the Covid-19 health crisis from the perspective of information behaviour: The case of Spain date: 2020-10-06 journal: nan DOI: 10.1177/0961000620949653 sha: doc_id: 33329 cord_uid: gi0mug1p
    keywords: authority; cases; cognitive; covid-19; crisis; fake; health; information; interactivity; knowledge; media; news; people; sources
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        item: #230 of 7819
          id: cord-033334-p7szd86k
      author: Mann, Jaclyn Kelly
       title: The potential of lactoferrin, ovotransferrin and lysozyme as antiviral and immune-modulating agents in COVID-19
        date: 2020-10-08
       words: 7291
      flesch: 23
     summary: Peptides in ovotransferrin that have high sequence homology with these bovine lactoferrin and human lactoferrin peptides acting against herpes simplex virus, human cytomegalovirus and adenovirus, were shown to have double the antiviral activity compared with the bovine lactoferrin peptides [72] . Damage of the outer membrane of enteric gram negative bacteria by lactoferrin and transferrin The antifungal activity of lactoferrin and its derived peptides: mechanisms of action and synergy with drugs against fungal pathogens Lactoferrin as a natural immune modulator Bovine lactoferrin supplementation supports immune and antioxidant status in healthy human males Lactoferrin accelerates reconstitution of the humoral and cellular immune response during chemotherapy-induced immunosuppression and bone marrow transplant in mice Human lactoferrin attenuates the proinflammatory response of neonatal monocyte-derived macrophages Lactoferrin in a context of inflammation-induced pathology Lactoferrin suppresses neutrophil extracellular traps release in inflammation Antihypertensive effects of lactoferrin hydrolyzates: inhibition of angiotensin-and endothelin-converting enzymes Lactoferrin, ovotransferrin & lysozyme in COVID-19 Review Aerosolized bovine lactoferrin counteracts infection, inflammation and iron dysbalance in a cystic fibrosis mouse model of Pseudomonas aeruginosa chronic lung infection Peptides affecting coagulation Antiviral activity of ovotransferrin derived peptides Ovotransferrin peptides that are conserved with peptides from bovine lactoferrin (which are also active against herpes simplex virus) were shown to be more potent than bovine lactoferrin peptides in their effect against Marek's disease virus Antiviral effect of ovotransferrin in mouse peritoneal macrophages by up-regulating type
    keywords: activity; bovine; covid-19; disease; effect; egg; human; immune; inflammation; iron; lactoferrin; lysozyme; ovotransferrin; peptides; sars; white
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        item: #231 of 7819
          id: cord-033356-ppn71yd0
      author: Abbott, Frederick M
       title: Facilitating Access to Cross-Border Supplies of Patented Pharmaceuticals: The Case of the COVID-19 Pandemic
        date: 2020-09-28
       words: 10043
      flesch: 38
     summary: The treaties administered by the World Intellectual Property Organization (WIPO) 23 and the World Trade Organization (WTO) 24 clearly allow for the grant by governments of compulsory patent licenses, that is, licenses granted without consent of patent owners. One should not assume that like-minded countries would be limited to LMICs, given that there are a number of Organisation for Economic Co-operation and Development (OECD) countries that have either issued compulsory patent licenses with respect to COVID-19 technologies or that have proposals to do so on the table.
    keywords: 31bis; agreement; article; compulsory; countries; governments; licenses; licensing; pharmaceutical; products; supply; treatments; trips; vaccines
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        item: #232 of 7819
          id: cord-033401-0o1g1924
      author: Jerry II, Robert H
       title: COVID-19: responsibility and accountability in a world of rationing
        date: 2020-09-12
       words: 6594
      flesch: 38
     summary: In the final analysis, in a public health emergency like the COVID-19 pandemic where demand for health care surges past available supply, health care providers must make life-ordeath decisions about the rationing of health care services. (writing in the context of COVID-19, authors state that -HCWs who take significant risks to provide care to other are leery of subsequent lawsuits Responders' Responsibility: Liability and Immunity in Public Health Emergencies Soc'y to Governor Jared Polis, -Liability Protection Expansions for Health Care Professionals on the Front Lines of the Coronavirus Pandemic state of disaster emergency declared [under state law]related to the COVID-19 public health emergency an Iowa state states that -[a] health care provider shall not be liable for civil damages for causing or contributing, directly or indirectly, to the death or injury of an individual as a result of the health care provider's acts or omissions while providing or arranging health care Utah statutory law states that -[a] health care provider is immune from civil liability for any harm resulting from any act or omission in the course of providing health care during a declared major public health emergency‖ for treatment of conditions that resulted in the declaration Alaska excludes liability for any health care provider -who takes action based on a standing order issued by the [Alaska] chief medical officer . . .
    keywords: act; care; covid-19; crisis; decisions; emergency; health; health care; liability; pandemic; providers; public; rationing; services; standard
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        item: #233 of 7819
          id: cord-033417-5elpvxhw
      author: Muthuppalaniappan, Menaka
       title: Healthcare Cyber-Attacks and the COVID-19 Pandemic: An Urgent Threat to Global Health
        date: 2020-09-27
       words: 1501
      flesch: 32
     summary: Healthcare institutions should be aware that they face additional risks in the context of any cyber-attack and ensure these are appropriately managed [6] . Underinvestment in cyber-security in healthcare institutions means some are particularly vulnerable to ransomware attacks, particularly during the COVID-19 pandemic.
    keywords: covid-19; cyber; healthcare; institutions
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        item: #234 of 7819
          id: cord-033420-pjtyv0pv
      author: Kalokairinou, Louiza
       title: The promise of direct-to-consumer COVID-19 testing: ethical and regulatory issues
        date: 2020-09-23
       words: 6323
      flesch: 43
     summary: Although the regulatory environment for COVID-19 tests is not identical to that for other types of DTC health tests (such as currently marketed genetic or hormone tests), 4 many of the concerns raised by DTC COVID-19 tests parallel those wrought by other types of DTC health tests. We conclude with recommendations for regulators, companies, and other relevant stakeholders that can help ensure high-quality, accurate, and equitably distributed COVID-19 tests, and inform the ethical provision of DTC health tests during public health crises.
    keywords: companies; concerns; consumer; covid-19; dtc; fda; health; healthcare; testing; tests
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        item: #235 of 7819
          id: cord-033453-557obi3r
      author: Bretscher, Lorenzo
       title: COVID-19 and the Cross-Section of Equity Returns: Impact and Transmission
        date: 2020-09-24
       words: 12248
      flesch: 61
     summary: In columns 1 and 2, the baseline sample, average nonfinancial firm return is 59.2 bps lower using raw returns and 60.4 bps lower using total returns than the benchmark return calculated from the two days immediately before the event day. In particular, we regress firm level returns on 15 dummies assigned to each day around the event.
    keywords: case; county; covid-19; day; days; dummy; event day; firms; labor; level; results; returns; sample; table; total
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        item: #236 of 7819
          id: cord-033481-3kxi7fd9
      author: Baker, Joseph O
       title: Religion in the Age of Social Distancing: How COVID-19 Presents New Directions for Research
        date: 2020-09-16
       words: 5005
      flesch: 27
     summary: Further, the death and mourning wrought by a pandemic would typically result in an increase in face-to-face gatherings and religious rituals; but given the need for social distancing and the necessity of adapting interaction to these constraints, the pandemic is triggering an increased need for religious traditions while at the same time significantly altering the expressions of those traditions. Immense pressure exists to re-open the economy out of a desperation to keep businesses running and to re-hire workers, with the use of phases to indicate the types of activities that could result (i.e., 1: bare essentials of food, health, and utilities; 2: limits on room capacity and enforced social distancing; 3: continued sanitization and expansion of social boundaries).
    keywords: church; covid-19; distancing; face; gatherings; groups; pandemic; religion; services
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        item: #237 of 7819
          id: cord-033505-bv705puy
      author: Rogado, Jacobo
       title: Characteristics and outcome of lung cancer patients and Covid-19 infection in a second-level hospital during the first 3 months of the pandemic()
        date: 2020-10-08
       words: 1172
      flesch: 47
     summary: J o u r n a l P r e -p r o o f SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, China Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan Covid-19 mortality in cancer patients in a Madrid hospital during the first 3 weeks of the epidemic Mortalidad por covid-19 en pacientes con cáncer en un hospital de Madrid durante las primeras 3 semanas de epidemia COVID-19 in patients with thoracic malignancies (TERAVOLT): first results of an international, registry-based, cohort study key: cord-033505-bv705puy authors: Rogado, Jacobo; Serrano-Montero, Gloria; Pangua, Cristina title: Characteristics and outcome of lung cancer patients and Covid-19 infection in a second-level hospital during the first 3 months of the pandemic() date: 2020-10-08 journal: Med Clin (Engl Ed) DOI: 10.1016/j.medcle.2020.07.005 sha: doc_id: 33505 cord_uid: bv705puy nan Scientific letter Characteristics and outcome of lung cancer patients and Covid-19 infection in a secondlevel hospital during the first 3 months of the pandemic Título:
    keywords: cancer; covid-19; mortality; patients
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        item: #238 of 7819
          id: cord-033550-47sqvg54
      author: Jain, Rachna
       title: Deep learning based detection and analysis of COVID-19 on chest X-ray images
        date: 2020-10-09
       words: 4407
      flesch: 54
     summary: J Francais D'Ophtalmologie Automatic X-ray COVID-19 lung image classification system based on multi-level Thresholding and support vector machine Covidx-net: a framework of deep learning classifiers to diagnose covid-19 in xray images Detection of Covid-19 from chest X-ray images using artificial intelligence: an early review Portable chest Xray in coronavirus disease-19 (COVID-19): a pictorial review Diagnosing COVID-19 pneumonia from X-ray and CT images using deep learning and transfer learning algorithms Coronavirus (COVID-19) classification using deep features fusion and ranking technique Automated detection of COVID-19 cases using deep neural networks with X-ray images Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Precise Prediction of COVID-19 in Chest X-Ray Images Using KE Sieve Algorithm Chest X-rays findings in COVID 19 patients at a University Teaching Hospital-A descriptive study Deep convolutional neural network based medical image classification for disease diagnosis Covid-19 screening on chest x-ray images using deep learning based anomaly detection Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study Chest X-ray (Covid-19 & Pneumonia) Deep learning is the most successful technique of machine learning, which provides useful analysis to study a large amount of chest x-ray images that can critically impact on screening of Covid-19.
    keywords: authors; chest; covid-19; disease; images; model; patients; ray
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        item: #239 of 7819
          id: cord-033655-16hj7sev
      author: Miroudot, Sébastien
       title: Reshaping the policy debate on the implications of COVID-19 for global supply chains
        date: 2020-10-12
       words: 8006
      flesch: 43
     summary: However, the literature does not regard supply chain risk as one of the main determinants of reshoring (Wiesmann, Snoei, Hilletofth, & Eriksson, 2017) . A new imperative related to the mitigation of supply chain risks can affect these decisions and change the geography and boundaries of firms, but the idea of reshoring seems simplistic as compared to the sophisticated location decisions described in the IB literature and the constraints faced by firms to remain competitive.
    keywords: chains; covid-19; firms; global; literature; management; policy; production; resilience; risk; supply; supply chains; value
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        item: #240 of 7819
          id: cord-033656-ivp3lchc
      author: Lim, Seok Mei
       title: Effects of the COVID-19 Pandemic on COVID-19 Negative Geriatric Patients with Hip Fractures
        date: 2020-10-09
       words: 853
      flesch: 50
     summary: In view of patient's persistent left hip pain, a magnetic resonance imaging (MRI) of left hip was done and confirmed a left NOF fracture. He represented three days later due to unbearable left hip pain, and finally agreed for surgical fixation.
    keywords: covid-19; hip; hospital
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        item: #241 of 7819
          id: cord-033660-rbhs15og
      author: Richards-Belle, Alvin
       title: Critical care outcomes, for the first 200 patients with confirmed COVID-19, in England, Wales and Northern Ireland: A report from the ICNARC Case Mix Programme
        date: 2020-10-08
       words: 3513
      flesch: 40
     summary: In Table 3 , we present critical care outcome, total duration of critical care, and receipt and duration of organ support (advanced respiratory, advanced cardiovascular and renal) in critical care for the first 200 consecutive patients compared with the figures previously published in ICNARC's weekly reports (results from alternate weeks' reports are presented). The UK is almost unique in producing critical care data so rapidly during this epidemic (as of 10 July 2020, on 12,793 admissions from 289 critical care units).
    keywords: care; covid-19; critical; data; duration; hospital; patients
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        item: #242 of 7819
          id: cord-033714-rz5unqaz
      author: Gupte, Jaideep
       title: COVID-19: what is not being addressed
        date: 2020-10-13
       words: 8228
      flesch: 43
     summary: In Kenya, the Muungano Alliance, in recognition of the impossibility of informal settlement residents isolating at home, has produced maps of informal settlements indicating places that are appropriate for isolation centres. (15) The gender gap is exacerbated in low-income areas; a study of informal settlements in Nairobi, Kampala, Lagos, Yaoundé, Maputo, Cairo, Bogotá, New Delhi, Jakarta and Manila revealed women are about 50 per cent less likely to be connected to the internet and a third less likely to use a smartphone to connect, compared to men in the same age group with similar levels of education and household income.
    keywords: access; cities; community; covid-19; global; government; health; income; informal; need; pandemic; people; research; residents; responses; services; settlements; urban
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        item: #243 of 7819
          id: cord-033759-cjxzenld
      author: Kang, Jaeho
       title: The Media Spectacle of a Techno-City: COVID-19 and the South Korean Experience of the State of Emergency
        date: 2020-08-17
       words: 4550
      flesch: 50
     summary: Analyzing the intensification of surveillance and the rapid datafication of society, this essay argues that the current state of emergency is not a breakdown of normality but a continuation of the state of crisis and disaster that rules a developing country like South Korea. 3 South Korea may deserve some credit for its handling of the coronavirus.
    keywords: coronavirus; covid-19; data; emergency; government; health; korea; society; south; south korea; state
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        item: #244 of 7819
          id: cord-033778-u2r0neyc
      author: Taban, EM
       title: Observational study of therapeutic bronchoscopy in critical hypoxaemic ventilated patients with COVID-19 at Mediclinic Midstream Private Hospital in Pretoria, South Africa
        date: 2020-10-13
       words: 2579
      flesch: 42
     summary: For patient 3, the procedure time was 2.5 hours with the lowest oxygen saturation recorded at 40% for 40 seconds and the procedure time for patient 11 was 55 minutes with the lowest oxygen saturation recorded at 36% for 24 seconds Patients 3, 5, 7 and 11 were extubated 72 hours after FFB to high -low nasal cannula and patients 1, 4, 6 and 9 are currently on minimal ventilator settings. [13] In our opinion, therapeutic FFB should be considered as an adjunctive therapy for COVID-19 patients with refractory hypoxaemia or even as a routine therapy around day 7 of mechanical ventilation if patients are slow to improve.
    keywords: bronchoscopy; covid-19; ffb; mucus; patients; type; ventilation
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        item: #245 of 7819
          id: cord-033780-184e64tr
      author: Smith, Rasheid
       title: Implications of current and future approaches to coronavirus disease 2019 testing
        date: 2020-10-13
       words: 3269
      flesch: 36
     summary: Emerging technologies such as graphene field-effect transistors have been used to detect as low as 1 fg/ml of SARS CoV-2 spike protein in transport medium for nasopharyngeal swabs and detect SARS-CoV-2 in clinical samples with readings obtained within 1 min Other cytokines and proteins can be implemented which are associated with increased severity of COVID-19 cases such as IL-2, IL-7, IL-10, G-CSF, IP-10 and cardiac troponin among others [13] .
    keywords: coronavirus; cov-2; covid-19; detection; disease; patients; pcr; sars; testing; tests
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        item: #246 of 7819
          id: cord-033820-3u3uybnt
      author: Rashid, Alina
       title: Pandemic anxiety and its correlates among young doctors working frontline in Pakistan
        date: 2020-09-30
       words: 2833
      flesch: 43
     summary: Overall, resident doctors working frontline during pandemic felt that COVID-19 impacted their interpersonal relationships. key: cord-033820-3u3uybnt authors: Rashid, Alina; Faisal, Kanza title: Pandemic anxiety and its correlates among young doctors working frontline in Pakistan date: 2020-09-30 journal: nan DOI: 10.1017/gmh.2020.22 sha: doc_id: 33820 cord_uid: 3u3uybnt BACKGROUND:
    keywords: covid-19; doctors; frontline; pandemic; patients; working
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        item: #247 of 7819
          id: cord-033827-ex1ahuc6
      author: Brooks, Deborah Jordan
       title: Double Whammy: Why the Underrepresentation of Women among Workplace and Political Decision Makers Matters in Pandemic Times
        date: 2020-08-18
       words: 2486
      flesch: 42
     summary: A related question is whether the preferences of female workers would be better represented by female workplace leaders as decision makers, which requires first identifying whether a similar gender gap regarding caution toward COVID-19 is also observed among their leaders. We also demonstrate that both female workers and female workplace leaders have fundamentally different preferences than men concerning COVID-19 in the workplace.
    keywords: covid-19; gender; leaders; women; workers; workplace
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        item: #248 of 7819
          id: cord-033833-woref5g8
      author: Fragoso-Saavedra, Sergio
       title: A parallel-group, multicenter randomized, double-blinded, placebo-controlled, phase 2/3, clinical trial to test the efficacy of pyridostigmine bromide at low doses to reduce mortality or invasive mechanical ventilation in adults with severe SARS-CoV-2 infection: the Pyridostigmine In Severe COvid-19 (PISCO) trial protocol
        date: 2020-10-16
       words: 2761
      flesch: 32
     summary: In addition to the approved uses of i-ACh-e in human pathology, there is evidence in various murine models of their efficacy in experimental sepsis and severe inflammatory response [12, 19, 21] , suggesting that i-ACh-e drugs have a potential immunomodulatory effect in patients with severe systemic inflammatory response syndrome. key: cord-033833-woref5g8 authors: Fragoso-Saavedra, Sergio; Iruegas-Nunez, David A.; Quintero-Villegas, Alejandro; García-González, H. Benjamín; Nuñez, Isaac; Carbajal-Morelos, Sergio L.; Audelo-Cruz, Belem M.; Arias-Martínez, Sarahi; Caro-Vega, Yanink; Calva, Juan José; Luqueño-Martínez, Verónica; González-Duarte, Alejandra; Crabtree-Ramírez, Brenda; Crispín, José C.; Sierra-Madero, Juan; Belaunzarán-Zamudio, Pablo F.; Valdés-Ferrer, Sergio I. title: A parallel-group, multicenter randomized, double-blinded, placebo-controlled, phase 2/3, clinical trial to test the efficacy of pyridostigmine bromide at low doses to reduce mortality or invasive mechanical ventilation in adults with severe SARS-CoV-2 infection: the Pyridostigmine In Severe COvid-19 (PISCO) trial protocol date: 2020-10-16 journal: BMC Infect Dis DOI: 10.1186/s12879-020-05485-7 sha: doc_id: 33833 cord_uid: woref5g8 BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the causative agent of coronavirus disease 2019 (COVID-19), may lead to severe systemic inflammatory response, pulmonary damage, and even acute respiratory distress syndrome (ARDS).
    keywords: covid-19; inflammatory; participants; patients; pyridostigmine; study; ventilation
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        item: #249 of 7819
          id: cord-033854-pub3lhiv
      author: van Zanten, Jan Anton
       title: Beyond COVID-19: Applying “SDG logics” for resilient transformations
        date: 2020-10-16
       words: 8400
      flesch: 43
     summary: The SDG agenda provides three ‘logics’ that could help transform towards sustainable societies: (1) a governance logic that sets goals, adopts policies, and tracks progress to steer impacts; (2) a systems (nexus) logic that manages SDG interactions; and (3) a strategic logic that enables (micro-level) companies to develop strategies that impact (macro-level) policy goals. The SDGs' systems logic works through the interactions between SDGs, in which contributions to one SDG can advance, but also deteriorate, progress on another SDG.
    keywords: agenda; business; companies; covid-19; development; economic; global; goals; logic; pandemic; sdgs; sustainability; sustainable; world
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        item: #250 of 7819
          id: cord-033882-uts6wfqw
      author: Khakharia, Aman
       title: Outbreak Prediction of COVID-19 for Dense and Populated Countries Using Machine Learning
        date: 2020-10-16
       words: 5857
      flesch: 60
     summary: Although the overall accuracy achieved was very good, we are still trying to implement prediction models using different algorithms that could give us higher accuracy. By using the data of these countries, we trained standard prediction models using multiple ML algorithms and obtained different accuracy for each of the models for different countries.
    keywords: accuracy; cases; countries; covid-19; data; error; model; number; prediction; values
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        item: #251 of 7819
          id: cord-033974-0rzi7x22
      author: Boyd, Rhea W
       title: In the 2020 US election, we can choose a just future
        date: 2020-10-19
       words: 1428
      flesch: 59
     summary: But while the founding fathers anchored their fledgling democracy in inequality, the expansion of US democracy owes its fragile progress to many forebearers, chief among them are the Indigenous, the formerly enslaved, and women. key: cord-033974-0rzi7x22 authors: Boyd, Rhea W; Krieger, Nancy; Jones, Camara Phyllis title: In the 2020 US election, we can choose a just future date: 2020-10-19 journal: Lancet DOI: 10.1016/s0140-6736(20)32140-1 sha: doc_id: 33974 cord_uid: 0rzi7x22 nan When US voters go to the polls (what few are left) or attempt to mail our ballots (with what remains of the US postal service) in the 2020 election, we are not simply choosing between two parties or posturing about partisan politics.
    keywords: administration; covid-19; democracy; health; people
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        item: #252 of 7819
          id: cord-033982-3slubbaf
      author: Avellanas Chavala, M.L.
       title: Pulmonary arterial hypertension and COVID-19()
        date: 2020-10-20
       words: 1281
      flesch: 46
     summary: Care of patients with pulmonary arterial hypertension during the coronavirus (COVID-19) pandemic Could pulmonary arterial hypertension patients be at a lower risk from severe COVID-19? key: cord-033982-3slubbaf authors: Avellanas Chavala, M.L. title: Pulmonary arterial hypertension and COVID-19() date: 2020-10-20 journal: nan DOI: 10.1016/j.medine.2020.05.006 sha: doc_id: 33982 cord_uid: 3slubbaf nan When hospitalized patients with pulmonary arterial hypertension (PAH) often fare worse compared to patients with other conditions.
    keywords: covid-19; hypoxia; pah; patients
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        item: #253 of 7819
          id: cord-034058-8lokg6hs
      author: Kim, In Kyung
       title: The impact of social distancing on box-office revenue: Evidence from the COVID-19 pandemic
        date: 2020-10-21
       words: 7854
      flesch: 55
     summary: Using longitudinal data on the Korean movie theater industry, I first estimate a nested logit model of movie demand, and then quantify the revenue loss in the industry. Second, some theaters were shutdown starting from late March, which might have further lowered movie demand.
    keywords: covid-19; demand; effect; industry; market; movie; movie demand; outbreak; revenue; table; week
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        item: #254 of 7819
          id: cord-034135-c3hjkcyh
      author: Valin, J.P.
       title: Physician Executives Guide a Successful Covid-19 Response in Colorado
        date: 2020-10-15
       words: 2088
      flesch: 37
     summary: By the end of July, Colorado had 47,745 cases of Covid-19 and our hospitals could boast clinical outcomes for Covid-19 patients that were better than the national average, including lower overall mortality rates, lower average length of stay, and fewer patients requiring mechanical ventilation ( Figure 1 ) Given their training and experience in emergency medicine, anesthesiology, family, internal and hospital medicine, infectious diseases, and pediatrics, the members of the group had a deep understanding of the challenges that frontline physicians faced in the care of Covid-19 patients.
    keywords: care; colorado; covid-19; group; patients
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        item: #255 of 7819
          id: cord-034156-adcnahpn
      author: Kim, Michael G.
       title: Fatal Cerebral Edema in a Child with COVID-19
        date: 2020-10-22
       words: 839
      flesch: 43
     summary: He was intubated and a CT scan of the head revealed new loss of gray-white differentiation with diffuse cerebral edema. Pathology slides showed diffuse cerebral edema in both the gray and white matter with perivascular mononuclear infiltrates, consistent with diffuse inflammation (Figure 1 ).
    keywords: covid-19; inflammatory; pediatric
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        item: #256 of 7819
          id: cord-034157-uif9xtvl
      author: Ortoleva, Jamel
       title: Anesthetic Considerations for Recovered COVID-19 Patients
        date: 2020-10-22
       words: 1245
      flesch: 23
     summary: Clinical Characteristics of Coronavirus Disease 2019 in China Covid-19 in Critically Ill Patients in the Seattle Region -Case Series Lung transplantation for COVID-19-associated acute respiratory distress syndrome in a PCR-positive patient Impact of coronavirus disease 2019 on pulmonary function in early convalescence phase Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery Pulmonary function in patients surviving to COVID-19 pneumonia Ventilatory support and mechanical properties of the fibrotic lung acting as a squishy ball Thrombosis in Hospitalized Patients With COVID-19 in a New York City Health System Thrombosis and coagulopathy in COVID-19 patients requiring extracorporeal membrane oxygenation Prevalence and Impact of Myocardial Injury in Patients Hospitalized With COVID-19 Infection Cardiovascular Magnetic Resonance Findings in Competitive Athletes Recovering From COVID-19 Infection Incidence of Stress Cardiomyopathy During the Coronavirus Disease 2019 Pandemic Dexamethasone in Hospitalized Patients with Covid-19 -Preliminary Report Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19: 17 Neurologic manifestations related to COVID-19 including stroke, intracranial hemorrhage, and critical illness myopathy related to prolonged intubation and immobility are important considerations in recovered COVID-19 patients.
    keywords: covid-19; patients; surgery
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        item: #257 of 7819
          id: cord-034181-ji4empe6
      author: Saqib, Mohd
       title: Forecasting COVID-19 outbreak progression using hybrid polynomial-Bayesian ridge regression model
        date: 2020-10-23
       words: 4642
      flesch: 46
     summary: Bayesian inference based approach is really important to conduct for COVID-19 pandemic rather than doing point estimations because it makes it possible to obtain probability density functions for model parameters and estimate the uncertainty that is important in the risk assessment analytics. In the Bayesian regression approach, we can take into account Other models are developed with good accuracy but as well as data become available, those entire algorithms will not able to survive without a few evaluations due to the dynamic nature of pandemic escalation of the COVID-19 but the proposed model corrects the distributions for model parameters and forecasting results using parameters distributions.
    keywords: bayesian; cases; covid-19; data; distribution; fig; model; pandemic; prediction
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        item: #258 of 7819
          id: cord-034195-yiv8rp7y
      author: Guhan, Samantha M.
       title: COVID-19 and healthcare disparities: Innovative ways to meet the dermatologic needs of patients experiencing homelessness
        date: 2020-10-23
       words: 546
      flesch: 41
     summary: We hypothesized that dermatologists can further aid this population by mobilizing 57 critical supplies commonly found in our offices and using the generosity of local companies to 58 create COVID-19 care kits, which contain items necessary to protect PEH from disease. The final kits contained soap, hand sanitizer, moisturizer, 67 The 2019 Annual 89 Homeless Assessment Report (AHAR) to Congress Assessment of 92 SARS-CoV-2 Infection Prevalence in Homeless Shelters -Four COVID-19 and Racial Disparities dental care products, puzzles, headphones, a COVID-19 informational pamphlet, and other 68 personal hygiene items ( Figure 1 ).
    keywords: covid-19; kits
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        item: #259 of 7819
          id: cord-034289-6y4437ah
      author: Xiao, Zhenxu
       title: Management of people with epilepsy during the COVID-19 pandemic: a national survey among epileptologists in China
        date: 2020-10-27
       words: 2568
      flesch: 52
     summary: A retrospective multicenter study Keeping people with epilepsy safe during the Covid-19 pandemic neurology Epilepsy care in the time of COVID-19 pandemic in Italy: risk factors for seizure worsening The effect of COVID-19 pandemic on seizure control and self-reported stress on patient with epilepsy Severe psychological distress among epilepsy patients during the COVID-19 outbreak in Southwest China In this article, we report the results of the survey and comment on the major problems and challenges of epilepsy management during the COVID-19 epidemic from the perspective of Chinese epileptologists.
    keywords: covid-19; epilepsy; patients; people; risk
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        item: #260 of 7819
          id: cord-034371-j3xxmkjd
      author: Schellack, Natalie
       title: COVID-19: Guidelines for pharmacists in South Africa
        date: 2020-06-10
       words: 5044
      flesch: 49
     summary: • Safe social (and professional) distancing of at least 1 metre between queueing patients (the use of floor markings is recommended) and between pharmacy personnel and patients across the counter • Appropriate respiratory hygiene (which includes the appropriate use of personal protective equipment (PPE) amongst staff and patients Therapeutic agents of concern Current information and guidance Non-steroidal anti-inflammatory drugs (NSAIDs) 4, 14, 23, 24, 25 • The use of ibuprofen (or other NSAIDs) in COVID-19 patients has been raised as a potential concern. In addition, COVID-19 patients have an increased risk of developing deep vein thrombosis (DVT) and pulmonary embolism (PE).
    keywords: contact; coronavirus; covid-19; disease; evidence; infection; patients; risk; treatment; use; virus
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        item: #261 of 7819
          id: cord-034373-7v7r44do
      author: Stevens, Jennifer P.
       title: Healthcare’s earthquake: Lessons from complex adaptive systems to develop Covid-19-responsive measures and models
        date: 2020-10-23
       words: 2340
      flesch: 45
     summary: Finally, as health care systems face increasing shifts in the pandemic, we propose identifying forecasting tools that provide opportunities to learn about the complex system of our health care environment and Covid-19 itself, rather than depending on unrealistic assumptions. One such example is the percentage of Covid-19 patients in our ICUs.
    keywords: care; covid-19; health; models; patients; systems
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        item: #262 of 7819
          id: cord-034398-g09usvbs
      author: Kumar, Santhi Iyer
       title: Filling the Bench: Faculty Surge Deployment in Response to the Covid-19 Pandemic
        date: 2020-10-29
       words: 1325
      flesch: 51
     summary: The next step involved matching information gained from the survey with the specific roles and responsibilities of faculty members. To ensure faculty members would be successful in their area of deployment, the hospitalists and intensivists created orientations to the Covid-19 patient care areas and designed processes and protocols that would support physicians unfamiliar with those clinical spaces.
    keywords: care; covid-19; faculty; surge
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        item: #263 of 7819
          id: cord-034435-yp0gfl47
      author: Medetalibeyoglu, A.
       title: Older Adults Hospitalized with Covid-19: Clinical Characteristics and Early Outcomes from a Single Center in Istanbul, Turkey
        date: 2020-10-08
       words: 4768
      flesch: 43
     summary: In conclusion, this study shows that older Covid-19 patients that were hospitalized presented with more prevalent chronic comorbidities, less prevalent symptomatology (i.e., cough and fever) but more severe respiratory signs and laboratory abnormalities than the younger patients. In the radiological evaluation, more than half of the patients (54.6%) had moderate-severe pneumonia, which was more prevalent in older patients (66% vs. 50%) (p=0.006).
    keywords: adults; covid-19; disease; laboratory; mortality; patients; pneumonia; study
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        item: #264 of 7819
          id: cord-034436-yhb8m1si
      author: Abdulah, Deldar Morad
       title: Relation of Dietary Factors with Infection and Mortality Rates of COVID-19 across the World
        date: 2020-07-04
       words: 3995
      flesch: 45
     summary: The study showed that the countries with higher infection rates between 1500 and above had a higher intake of fruits (P=0.002), fruit juices (P<0.001), calcium (P<0.001), potassium (P<0.001), and total milk (P<0.001). Therefore, we can make the further hypothesis that the aged population of the countries with high infection rates has been the main factor in the low immune system.
    keywords: countries; covid-19; fruits; immune; infection; intake; mortality; rate
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        item: #265 of 7819
          id: cord-034438-9kdmljoq
      author: Sepúlveda-Loyola, W.
       title: Impact of Social Isolation Due to COVID-19 on Health in Older People: Mental and Physical Effects and Recommendations
        date: 2020-09-25
       words: 4723
      flesch: 32
     summary: The social distancing has reduced the levels of physical activity, which could have a negative impact on physical health (43, 44) . A 10-year follow-up of the Aichi Gerontological Evaluation Study Associations between social isolation, loneliness, and objective physical activity in older men and women Social isolation, C-reactive protein, and coronary heart disease mortality among community-dwelling adults Loneliness and risk of mortality: a longitudinal investigation in Alameda County Loneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies Social isolation and physical inactivity in older US adults: Results from the Third National Health and Nutrition Examination Survey Sedentary Behavior Research Network (SBRN) -Terminology Consensus Project process and outcome Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research Sedentary behavior and health outcomes among older adults: a systematic review Physical activity in non-frail and frail older adults Replacing sedentary time with physical activity: a 15-year follow-up of mortality in a national cohort Reallocating Accelerometer-Assessed Sedentary Time to Light or Moderate-to Vigorous-Intensity Physical Activity Reduces Frailty Levels in Older Adults: An Isotemporal Substitution Approach in the TSHA Study The Feasibility and Longitudinal Effects of a Home-Based Sedentary Behavior Change Intervention After Stroke COVID-19, Mental Health and Aging: A Need for New Knowledge to Bridge Science and Service Declaration of Conflict of Interest: None.Declaration of Sources of Funding: co-financed by the European Regional Development Funds (RD120001/0043) and the Centro de Investigación Biomédica en Red en Fragilidad y Envejecimiento Saludable-CIBERFES (CB16/10/00464).Author's contribution: Study concept and design: all authors.
    keywords: activity; adults; covid-19; health; isolation; pandemic; participation; people; physical; review
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        item: #266 of 7819
          id: cord-034443-rptylxmw
      author: Morley, John E.
       title: COVID-19 — The Long Road to Recovery
        date: 2020-10-05
       words: 1796
      flesch: 28
     summary: All persons with COVID-19 should have bioavailable 25(OH) vitamin D measured (15) as during lockdown lack of sunlight can markedly reduce vitamin D in COVID-19 patients (16) . Nature (News feature) Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery Back to basics: Giant challenges to addressing Isaac's Geriatric Giants post COVID-19 crisis COVID-19 and associations with frailty and multimorbidity: A prospective analysis of UK Biobank participants The association between frailty and severe disease among COVID-19 patients aged over 60 years in China: A prospective cohort study COVID-19: A major cause of cachexia and sarcopenia?
    keywords: care; covid-19; delirium; patients; persons; study
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        item: #267 of 7819
          id: cord-034466-e6kg0yx9
      author: Al-Zaidi, Haider Majid Haider
       title: Incidence and recovery of smell and taste dysfunction in COVID-19 positive patients
        date: 2020-10-31
       words: 1694
      flesch: 56
     summary: Many other recent studies found that smell and taste dysfunctions are seen frequently in COVID-19 patients [4] . A novel syndrome? Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Axonal transport enables neuron-to-neuron propagation of human coronavirus OC43 Objective evaluation of anosmia and ageusia in COVID-19 patients: single-center experience on 72 cases Presentation of new onset anosmia during the COVID-19 pandemic Olfactory and gustatory function impairment in COVID-19 patients: Italian objective multicenterstudy Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study Self-reported Olfactory and Taste Disorders in Patients With Severe Acute Respiratory Coronavirus 2 Infection: A Cross-sectional Study Early recovery following new onset anosmia during the COVID-19 pandemic -an observational cohort study Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak in Iran We are grateful to the help of Dr. Abdul Kareem Sadiq Kareem, vice director of Al-Shifaa hospital in Baghdad, who facilitated data collection.
    keywords: covid-19; dysfunction; patients; taste
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        item: #268 of 7819
          id: cord-034495-gvtv8o96
      author: Hussain, Kashif
       title: Pharmacy services during COVID-19 pandemic: experience from a tertiary care teaching hospital in Pakistan
        date: 2020-11-02
       words: 2658
      flesch: 40
     summary: Improving patient safety and work quality involve coordinated efforts of multidisciplinary health care team, including clinical pharmacist as the vital team member. Activities redesigned and now clinical pharmacists are doing round virtually specifically in COVID-19 unit.
    keywords: care; covid-19; health; hospital; pandemic; patients; pharmacy; staff
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        item: #269 of 7819
          id: cord-034517-ygiqrmbw
      author: Wieland, Mark L.
       title: Leveraging community engaged research partnerships for crisis and emergency risk communication to vulnerable populations in the COVID-19 pandemic
        date: 2020-05-15
       words: 3021
      flesch: 31
     summary: Additionally, Communication Leaders solicited community health and socioeconomic concerns through the same platforms. Communication Leaders were recruited by RHCP community partners to deliver messages based on their credibility and trustworthiness within subset communities.
    keywords: communication; community; covid-19; intervention; leaders; messages; partners; risk
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        item: #270 of 7819
          id: cord-034603-9gso0zib
      author: Dungar, Keval Dhanji
       title: Can surgery continue safely during a pandemic? A commentary on “Surgical activity during the Covid-19 pandemic: Results for 112 patients in a French tertiary care center, a quality improvement study”
        date: 2020-11-04
       words: 892
      flesch: 47
     summary: A key consideration for conducting safe surgery during the pandemic, is to ensure rigorous testing of each patient before surgery and then managing them accordingly. 'COVID-free' areas may indeed be paramount to ensuring that safe surgery may continue without complications due to COVID-19.
    keywords: covid-19; surgery
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        item: #271 of 7819
          id: cord-034614-r429idtl
      author: Yasar, Huseyin
       title: A new deep learning pipeline to detect Covid-19 on chest X-ray images using local binary pattern, dual tree complex wavelet transform and convolutional neural networks
        date: 2020-11-04
       words: 7769
      flesch: 54
     summary: The first Vietnamese case of COVID-19 acquired from China The role of augmented intelligence (ai) in detecting and preventing the spread of novel coronavirus An automated residual exemplar local binary pattern and iterative ReliefF based corona detection method using lung X-ray image Application of deep learning for fast detection of COVID-19 in X-rays using nCOVnet Automated detection of COVID-19 cases using deep neural networks with X-ray images Benchmarking methodology for selection of optimal COVID-19 diagnostic model based on entropy and TOPSIS methods Coronet: a deep neural network for detection and diagnosis of COVID-19 from chest x-ray images Covid-19: automatic detection from x-ray images utilizing transfer learning with convolutional neural networks Covidgan: data augmentation using auxiliary classifier Gan for improved covid-19 detection CovXNet: a multidilation convolutional neural network for automatic COVID-19 and other pneumonia detection from chest X-ray images with transferable multi-receptive feature optimization Deep learning COVID-19 detection bias: accuracy through artificial intelligence Deep transfer learning with apache spark to detect COVID-19 in chest X-ray images New machine learning method for image-based diagnosis of COVID-19 Performance evaluation of the NASNet convolutional network in the automatic identification of COVID-19 Within the lack of chest COVID-19 X-ray dataset: a novel detection model based on GAN and deep transfer learning Convolutional capsnet: a novel artificial neural network approach to detect COVID-19 disease from X-ray images using capsule networks COVID-XNet: a custom deep learning system to diagnose and locate COVID-19 in chest X-ray images Deepcovid: predicting covid-19 from chest x-ray images using deep transfer learning COVID-19 image data collection COVID-19 X rays Two public chest X-ray datasets for computer-aided screening of pulmonary diseases A comparative study of texture measures with classification based on featured distributions The dual-tree complex wavelet transform The dual-tree complex wavelet transform: a new efficient tool for image restoration and enhancement Shift invariant properties of the dual-tree complex wavelet transform Dual-tree complex wavelet transform and SVD based medical image resolution enhancement A novel method for lung segmentation on chest CT images: complex-valued artificial neural network with complex wavelet transform Blood vessel extraction from retinal images using complex wavelet transform and complex-valued artificial neural network Improved adaptive image retrieval with the use of shadowed sets Uncertainty-optimized deep learning model for small-scale person re-identification Vehicle and wheel detection: a novel SSD-based approach and associated large-scale benchmark dataset Kernel pooling for convolutional neural networks Deep metric learning with angular loss A study on the cardinality of ordered average pooling in visual recognition Data augmentation for eeg-based emotion recognition with deep convolutional neural networks A modified convolutional neural network for face sketch synthesis A novel comparative study for detection of Covid-19 on CT lung images using texture analysis, machine learning, and deep learning methods A novel comparative study using multi-resolution transforms and convolutional neural network (CNN) for contactless palm print verification and identification A face recognition method based on LBP feature for CNN. Appl Intell DOI: 10.1007/s10489-020-02019-1 sha: doc_id: 34614 cord_uid: r429idtl In this study, which aims at early diagnosis of Covid-19 disease using X-ray images, the deep-learning approach, a state-of-the-art artificial intelligence method, was used, and automatic classification of images was performed using convolutional neural networks (CNN).
    keywords: cnn; covid-19; data; images; pipeline; ray images; results; study; test; training
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        item: #272 of 7819
          id: cord-034629-uusqhsnf
      author: Eufemia, Luca
       title: Peacebuilding in times of COVID-19: risk-adapted strategies of cooperation and development projects
        date: 2020-11-04
       words: 3418
      flesch: 28
     summary: Peace-process Regional coordinator Geographies of peace and violence during conflict: the case of the Alavanyo-Nkonya boundary dispute in Ghana COVID-19 is a window of opportunity for Peacebuilding-use it!, peacelab-Blog Using social and behavioural science to support COVID-19 pandemic response Re-thinking recovery in post-conflict settings: supporting the mental well-being of communities in Colombia Finally, the development of project strategies that address risks and uncertainty can be better guided by social learning processes.
    keywords: cdps; colombia; conflict; covid-19; future; peacebuilding; projects; strategies
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        item: #273 of 7819
          id: cord-034640-ygtbuy4k
      author: None
       title: Corrigenda
        date: 2020-11-04
       words: 265
      flesch: 29
     summary: COVID-19: start with the nose SARS-CoV-2 reverse genetics reveals a variable infection gradient in the respiratory tract Detection of rhinovirus RNA in lower airway cells during experimentally induced infection Effect of dexamethasone in hospitalized patients with COVID-19: preliminary report Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2 ), it has been brought to the Editors' attention that the authors' names were incorrect as printed. key: cord-034640-ygtbuy4k authors: nan title: Corrigenda date: 2020-11-04 journal: J Allergy Clin Immunol DOI: 10.1016/j.jaci.2020.08.023 sha: doc_id: 34640 cord_uid: ygtbuy4k nan corticosteroids on COVID-19 outcomes.
    keywords: covid-19
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        item: #274 of 7819
          id: cord-034660-g28qmyh8
      author: Sciamanna, Christopher
       title: Using Persuasion Science to Improve COVID-19 Contact Tracing
        date: 2020-11-05
       words: 1374
      flesch: 51
     summary: I'm not sure if someone told you that other people will be calling, but I work with infection control and my team's job is to talk to people who have been diagnosed with COVID and find out all of the people who they have been in contact with, so we can get those people to quarantine themselves. We present them here for use by others as we are concerned that, as contact tracing is scaled nationwide, it may be significantly less effective than it could otherwise be.
    keywords: contact; help; people
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        item: #275 of 7819
          id: cord-034686-y0y5ltxs
      author: Gieraerts, Christopher
       title: Prognostic Value and Reproducibility of AI-assisted Analysis of Lung Involvement in COVID-19 on Low-Dose Submillisievert Chest CT: Sample Size Implications for Clinical Trials
        date: 2020-10-22
       words: 3170
      flesch: 42
     summary: AI-powered analysis of lung involvement was performed at a dedicated workstation using CT pneumonia analysis v.2.0. Overall, no significant bias was observed with Bland-Altman analysis along the different types of CT analysis (Table 4, Figure 3 ).
    keywords: analysis; chest; covid-19; involvement; lung; patients; visual
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        item: #276 of 7819
          id: cord-034689-se1hdn61
      author: Smith, David L.
       title: A Characteristic Chest Radiographic Pattern in the Setting of COVID-19 Pandemic
        date: 2020-09-03
       words: 2920
      flesch: 43
     summary: Rather, these societies recommend CT use be reserved for management of COVID-19 patients with worsening and/or severe respiratory symptoms, in particular for those in a hospital setting or those having special indications for CT Characteristic CXR of a 63-year-old female presenting with dyspnea and fever.
    keywords: chest; covid-19; cxr; patients; pcr
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        item: #277 of 7819
          id: cord-034690-x8lkngra
      author: Ridge, Carole A
       title: Dual-Energy CT Pulmonary Angiography (DECTPA) Quantifies Vasculopathy in Severe COVID-19 Pneumonia
        date: 2020-10-29
       words: 3220
      flesch: 35
     summary: Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Coronavirus Disease 2019 (COVID-19): Role of Chest CT in Diagnosis and Management Pulmonary High-Resolution Computed Tomography (HRCT) Findings of Patients with Early-Stage Coronavirus Disease 2019 (COVID-19) in Hangzhou, China Clinical features of patients infected with 2019 novel coronavirus in Wuhan Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China COVID-19 pneumonia: different respiratory treatments for different phenotypes? Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Clinical and immunological features of severe and moderate coronavirus disease 2019 Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Acute pulmonary embolism and COVID-19 pneumonia: a random association? COVID-19 Complicated by Acute Pulmonary Embolism Ventilatory Ratio in Hypercapnic Mechanically Ventilated Patients with COVID-19-associated Acute Respiratory Distress Syndrome Hypoxaemia related to COVID-19: vascular and perfusion abnormalities on dual-energy CT Pulmonary angiopathy in severe Covid-19: physiologic, imaging and hematologic observations Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19 Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans Pulmonary infarction secondary to pulmonary thromboembolism in COVID-19 diagnosed with dual-energy CT pulmonary angiography Radiology: Pulmonary Vascular Manifestations of COVID-19 Pneumonia Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19: Report of the National Institute for Public Health of the Netherlands Pulmonary Embolism on CTPA in COVID-19 Patients Clinical Significance of Late Phase of Lung Perfusion Blood Volume (Lung Perfusion Blood Volume) Quantified by Dual-Energy Computed Tomography in Patients With Pulmonary Thromboembolism New CT index to quantify arterial obstruction in pulmonary embolism: comparison with angiographic index and echocardiography Correlation analysis of dual-energy CT iodine maps with quantitative pulmonary perfusion MRI Segmental Anatomy of the Lungs Dualenergy CT angiography for assessment of regional pulmonary perfusion in patients with chronic thromboembolic pulmonary hypertension: initial experience Dual-energy CT for imaging of pulmonary hypertension: challenges and opportunities Dual-energy CT for the assessment of contrast material distribution in the pulmonary parenchyma Pulmonary vasospasm in systemic sclerosis: noninvasive techniques for detection The Spectrum of Cardiac Manifestations in Coronavirus Disease 2019 (COVID-19) -a As future randomized controlled trials are devised, we suggest that DECTPA is used as a surveillance tool, to determine whether the temporal pattern of pulmonary perfusion represents the natural history of the disease, or an anticoagulation-related effect.
    keywords: covid-19; disease; paenh; patients; pbv; perfusion; pneumonia; pulmonary
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        item: #278 of 7819
          id: cord-034691-cw1311qg
      author: Grodecki, Kajetan
       title: Quantitative Burden of COVID-19 Pneumonia on Chest CT Predicts Adverse Outcomes: A Post-Hoc Analysis of a Prospective International Registry
        date: 2020-10-01
       words: 3692
      flesch: 36
     summary: Chest CT Findings in Coronavirus Disease-19 (COVID-19): Relationship to Duration of Infection Well-aerated Lung on Admitting Chest CT to Predict Adverse Outcome in COVID-19 Pneumonia Multicenter cohort study demonstrates more consolidation in upper lungs on initial CT increases the risk of adverse clinical outcome in COVID-19 patients Computed Tomographic Features and Short-term Prognosis of Coronavirus Disease Chest CT Severity Score: An Imaging Tool for Assessing Severe COVID-19 CT image visual quantitative evaluation and clinical classification of coronavirus disease (COVID-19) Automatic lung segmentation in routine imaging is a data diversity problem, not a methodology problem Lung tissue characterization for emphysema differential diagnosis using deep convolutional neural networks: SPIE Fleischner Society: glossary of terms for thoracic imaging Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study Critical Supply Shortages -The Need for Ventilators and Personal Protective Equipment during the Covid-19 Pandemic Facing Covid-19 in Italy -Ethics, Logistics, and Therapeutics on the Epidemic's Front Line Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period Pathological study of the 2019 novel coronavirus disease (COVID-19) through postmortem core biopsies Postmortem Examination of Patients With COVID-19 Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study C-Reactive Protein Level May Predict the Risk of COVID-19 Aggravation Prognostic value of C-reactive protein in patients with Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. The optimal cutoff values for COVID-19 pneumonia burden as I n p r e s s 13 determined by Youden's index were GGO of greater than or equal to 13.5% and consolidation of greater than or equal to 1.8%, above which there was a steep increase in the risk of deterioration and death with OR of 5.1 (95% CI: 1.5, 3.6; P = .008) and an OR of 4.8 (95% CI: 1.5, 10.2, P = .007)
    keywords: burden; chest; consolidation; covid-19; death; disease; lung; patients; pneumonia
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        item: #279 of 7819
          id: cord-034814-flp6s0wd
      author: Lamsal, Rabindra
       title: Design and analysis of a large-scale COVID-19 tweets dataset
        date: 2020-11-06
       words: 5521
      flesch: 55
     summary: Saving thousands of tweets information every minute triggers continuous writing activity on the disk. Twitter's content redistribution policy restricts the sharing of tweet information other than tweet IDs, Direct Message IDs and/or User IDs.
    keywords: analysis; covid-19; dataset; geo; hashtags; ids; information; pandemic; sentiment; study; tweets; twitter
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        item: #280 of 7819
          id: cord-034942-ezwt39rq
      author: Asayama, Shinichiro
       title: Are we ignoring a black elephant in the Anthropocene? Climate change and global pandemic as the crisis in health and equality
        date: 2020-11-07
       words: 4537
      flesch: 44
     summary: But this now famous line of hers also raises an important question: What kind of crisis climate change is and what does treating a crisis as a crisis really mean? There are mounting concerns over the impacts of climate change on human health (Watts et al. 2019 ).
    keywords: change; climate; covid-19; crisis; et al; health; human; pandemic; sustainability
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        item: #281 of 7819
          id: cord-034952-hctfmjhv
      author: D'Avanzo, Barbara
       title: What changed in the Italian internal medicine and geriatric wards during the lockdown
        date: 2020-11-07
       words: 974
      flesch: 47
     summary: Twenty wards, corresponding to 37% of the 48 which answered, were converted into COVID-19 wards. Professionals were transferred to COVID-19 wards from a variety of different subspecialty wards (including a certain number of physicians and nurses already retired), hospital admissions were restricted to severe or urgent conditions, so that clinical research were mostly interrupted.
    keywords: covid-19; cws; wards
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        item: #282 of 7819
          id: cord-035015-slgywe0c
      author: Nunn, Alistair V. W.
       title: SARS-CoV-2 and mitochondrial health: implications of lifestyle and ageing
        date: 2020-11-09
       words: 14677
      flesch: 27
     summary: Critically, it modulates mitochondrial function, having diverse affects depending on the tissue; it can stimulate muscle mitochondrial function [241] , but may also enhance lipid storage and adipogenesis [242] . As the immune system itself is heavily reliant on mitochondrial function, then maintaining a healthy mitochondrial system may play a key role in resisting the virus, both directly, and indirectly by ensuring a good vaccine response.
    keywords: ace2; age; anti; cell; cov-2; covid-19; data; exercise; function; health; immune; inflammasome; inflammation; key; metabolic; mitochondrial; oxidative; patients; response; role; ros; sars; stress; system; virus
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        item: #283 of 7819
          id: cord-035016-ipv8npdy
      author: Torreele, Els
       title: Business-as-Usual will not Deliver the COVID-19 Vaccines We Need
        date: 2020-11-09
       words: 5575
      flesch: 31
     summary: The ‘race’ for COVID-19 vaccines is exposing the deficiencies of a business-as-usual medical innovation ecosystem driven by corporate interests, not health outcomes. In April 2020, the World Health Organization (WHO) published a Target Product Profile 4 (TPP) for COVID-19 vaccines with minimal and ideal vaccine characteristics to guide developers.
    keywords: access; companies; covid-19; efficacy; global; health; public; r&d; technologies; trials; vaccine
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        item: #284 of 7819
          id: cord-035020-mhs7yext
      author: Simadibrata, Daniel Martin
       title: Platelet-to-lymphocyte ratio, a novel biomarker to predict the severity of COVID-19 patients: A systematic review and meta-analysis
        date: 2020-11-02
       words: 3252
      flesch: 45
     summary: However, with the removal of Yang et al., the pooled analysis still showed a statistically significant higher PLR value on admission in severe COVID-19 in comparison to non-severe COVID-19 patients. The pooled effect size meta-analysis using the fixedeffects model showed a significantly higher PLR value on admission in severe COVID-19 patients than non-severe COVID-19 patients (SMD 0.57; 95%CI 0.41-0.72).
    keywords: admission; analysis; covid-19; patients; plr; severity; studies
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        item: #285 of 7819
          id: cord-035023-kviogc6h
      author: Harrison, Stephanie L.
       title: End-Stage Renal Disease and 30-day Mortality for Adults with and without COVID-19
        date: 2020-11-09
       words: 1430
      flesch: 46
     summary: By comparing people with ESRD and COVID-19 to historical matched controls with ESRD without COVID-19, the results of the current study suggest that COVID-19 infection further increases mortality nearly 4-fold in people with ESRD. Stephanie ESRD: end stage renal disease.
    keywords: controls; covid-19; esrd; patients
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        item: #286 of 7819
          id: cord-035026-2qcsfd87
      author: Ugwueze, Chidiebere V.
       title: COVID-19 and Diabetes Mellitus: The Link and Clinical Implications
        date: 2020-10-23
       words: 5416
      flesch: 39
     summary: Diabetes mellitus is one of commonest noncommunicable diseases associated with worsening clinical status in COVID-19 patients. Pathogenetic mechanisms such as impaired immunity, microangiopathy, and glycemic variability may explain the effect of diabetes on recovery of COVID-19 patients.
    keywords: ace2; coronavirus; covid-19; diabetes; disease; effect; infection; insulin; patients; receptor; sars; type
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        item: #287 of 7819
          id: cord-035038-iefkv5g7
      author: Leal Filho, Walter
       title: COVID-19: the impact of a global crisis on sustainable development research
        date: 2020-11-09
       words: 7332
      flesch: 36
     summary: Based on this framework, the crisis caused by COVID-19 has posed new challenges for sustainability research, and it is relevant to study how a global crisis influences such research. There is a gap in the literature in regards to how a global crisis influences sustainability research.
    keywords: coronavirus; covid-19; crisis; development; et al; impact; pandemic; research; researchers; sample; study; support; sustainability; sustainability research; technologies
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        item: #288 of 7819
          id: cord-035042-umufaixr
      author: Inui, Shohei
       title: Comparison of Chest CT Grading Systems in Coronavirus Disease 2019 (COVID-19) Pneumonia
        date: 2020-11-05
       words: 3951
      flesch: 38
     summary: The published CT grading systems of chest CT findings in COVID-19 patients may facilitate both making the radiological diagnosis and smooth communication among professionals in other fields, and their applicability and validity in the clinical practice was recently reported in several studies [7, 8, 9, 10] . This prompted us to undertake the present study to validate the performance and interobserver agreement of four sets of CT grading systems, including the COVID-19 Reporting and Data System (CO-RADS), the COVID-19 imaging reporting and data system (COVID-RADS), the RSNA expert consensus statement and the BSTI guidance statement.
    keywords: covid-19; grading; patients; rads; statement; study; system
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        item: #289 of 7819
          id: cord-035044-duzoa2v7
      author: Sondermann, Elena
       title: The threat of thinking in threats: reframing global health during and after COVID-19
        date: 2020-11-09
       words: 4643
      flesch: 46
     summary: Although the narrative of global health security is characterized by two distinct variants, with the concept of human security opening up the space to think of how individuals and their rights are affected by inequalities, both variants are firmly rooted in depicting health threats as exceptional and existential to our lives. These vulnerabilities are not only due to changing global health threats.
    keywords: countries; covid-19; diseases; global; health; narrative; pandemic; security; threat
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        item: #290 of 7819
          id: cord-035067-ic843wr9
      author: de Almeida, Joana Ferro Machado
       title: COVID-19 and the gastrointestinal tract: what do we already know?
        date: 2020-11-05
       words: 5454
      flesch: 50
     summary: SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues ACE-2 expression in the small airway epithelia of smokers and COPD Patients: Implications for COVID-19 COVID-19 and diabetes: Knowledge in progress Association of angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use with covid-19 diagnosis and mortality Association of renin-angiotensin system inhibitors with severity or risk of death in patients with hypertension hospitalized for coronavirus disease 2019 (COVID-19) infection in Wuhan, China Emerging WuHan (COVID-19) coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26 Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China Enteric involvement in hospitalised patients with COVID-19 outside Wuhan Prevalence and characteristics of gastrointestinal symptoms in patients with SARS-CoV-2 infection in the United States: a multicenter cohort study Gastrointestinal symptoms and COVID-19: case-control study from the United States High prevalence of concurrent gastrointestinal manifestations in patients with SARS-CoV-2: early experience from California Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Effect of gastrointestinal symptoms on patients infected with COVID-19 Gastrointestinal manifestations of SARS-CoV-2 infection and virus load in fecal samples from the Hong Kong cohort and systematic review and meta-analysis Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2: a systematic review and meta-analysis COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis Gastrointestinal infection could be new focus for coronavirus diagnosis Individual variation of the SARS-CoV2 receptor ACE2 gene expression and regulation Those infected may be asymptomatic, present typical symptoms (fever, dry cough and dyspnea), gastrointestinal symptoms (diarrhea, nausea, vomiting and abdominal pain) and viral RNA in stools.
    keywords: cov-2; covid-19; disease; patients; sars; studies; study; symptoms; viral; virus
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        item: #291 of 7819
          id: cord-035070-drt6esrk
      author: Cheng, Yichun
       title: Risk Factors and Outcomes of Acute Kidney Injury in Critically Ill Patients with Coronavirus Disease 2019
        date: 2020-10-26
       words: 3664
      flesch: 49
     summary: In accordance with the recent reports on the outcomes of COVID-19 patients, 5-26% of patients will be admitted to the intensive care unit during hospitalization [4] [5] [6] . However, due to the small number of patients and the bias in a different therapy of COVID-19 patients, the causal relationship between medications and AKI in critically ill COV-ID-19 patients remains undetermined.
    keywords: aki; covid-19; hospital; kidney; mortality; patients; severe; study
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        item: #292 of 7819
          id: cord-035077-qjrokb17
      author: Konstantinov, Vsevolod
       title: COVID-19 Impact on Kazakhstan University Student Fear, Mental Health, and Substance Use
        date: 2020-11-09
       words: 1978
      flesch: 41
     summary: Based on earlier COVID-19 research of university students in Russia and Belorussia, we hypothesize COVID-19 fear, mental health, and substance use among Kazakh university students are linked to gender and religious status. The influence of COVID-19 on student substance use including tobacco, alcohol, cannabis, and prescription drugs was examined.
    keywords: covid-19; fear; students; use
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        item: #293 of 7819
          id: cord-035095-wo5fq359
      author: Zubieta-Calleja, Gustavo
       title: Pneumolysis and “Silent Hypoxemia” in COVID-19
        date: 2020-11-09
       words: 2405
      flesch: 40
     summary: This value is remarkably similar to SpO 2 \ 90% (even with FIO 2 60%) in COVID-19 patients requiring ventilators at sea level. We compare medical and physiological high altitude acute and chronic hypoxia experience with COVID-19 hypoxemia.
    keywords: altitude; covid-19; hypoxemia; hypoxia; lung; patients; pneumolysis; pulmonary
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        item: #294 of 7819
          id: cord-035098-zmv0ngf0
      author: Li, Daqiu
       title: Stacked-autoencoder-based model for COVID-19 diagnosis on CT images
        date: 2020-11-09
       words: 5819
      flesch: 53
     summary: After the whole model is trained, we get the end-to-end stack autoencoder detection model. The artificial intelligence method for CT image detection of COVID-19 have the advantages of fast speed, low cost, and high accuracy.
    keywords: autoencoder; covid-19; feature; layer; loss; model; network; training
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        item: #295 of 7819
          id: cord-035099-8yk0dzxf
      author: Brika, Marine
       title: Geriatric Rehabilitation and COVID-19: a Case Report
        date: 2020-11-09
       words: 3033
      flesch: 42
     summary: Mr. P is a 93-year-old frail patient, hospitalized after a COVID-19 infection. The care plan was developed accordingly, and four assessments were done in the same manner until Mr. P returned home.
    keywords: adults; covid-19; exercises; frailty; patient; rehabilitation; test
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        item: #296 of 7819
          id: cord-035113-bhnv2qbi
      author: Senapati, Apurbalal
       title: A novel framework for COVID-19 case prediction through piecewise regression in India
        date: 2020-11-10
       words: 2910
      flesch: 55
     summary: key: cord-035113-bhnv2qbi authors: Senapati, Apurbalal; Nag, Amitava; Mondal, Arunendu; Maji, Soumen title: A novel framework for COVID-19 case prediction through piecewise regression in India date: 2020-11-10 journal: Int J Inf Technol DOI: 10.1007/s41870-020-00552-3 sha: doc_id: 35113 cord_uid: bhnv2qbi Outbreak of COVID-19, created a disastrous situation in more than 200 countries around the world. The magnitude of relative error (MRE) and mean absolute percentage error (MAPE) are mostly used to measure the accuracy of regression based prediction model
    keywords: cases; covid-19; data; model; number; regression
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        item: #297 of 7819
          id: cord-035137-uxtaw02u
      author: Chowdhury, Anis Z.
       title: Responding to the COVID-19 Pandemic in Developing Countries: Lessons from Selected Countries of the Global South
        date: 2020-11-10
       words: 6831
      flesch: 46
     summary: Finally, it draws some implications of different policy responses in East Asia, Southeast Asia-especially Vietnam, and India's Kerala state-Argentina, Brazil and Peru, that are relevant for other countries. Earlier in April, President Trump, using a Korean War-era law, sought to redirect surgical masks manufactured by the US transnational firm 3M in other countries to the US, and to stop exporting masks manufactured by the company in the US (Swanson et al. 2020 ).
    keywords: countries; covid-19; distancing; government; health; kerala; lockdowns; masks; measures; pandemic; people; policy; ppe; vietnam; virus; world
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        item: #298 of 7819
          id: cord-035138-7v92aukg
      author: Tognoni, Gianni
       title: Health as a Human Right: A Fake News in a Post-human World?
        date: 2020-11-10
       words: 5060
      flesch: 41
     summary: The iteration of strictly descriptive and repetitive data on the growing notavoidable levels of inequalities-inequities has paved the way to the planned disappearance even from the dictionaries of health rights disciplines (Abassi 2020) . Until the arrival of a biological agent, doomed to be under global knowledge's tight control, has successfully revealed the inherent ignorance and deep fragmentation defining the various branches of the most advanced disciplines of basic sciences: public health, epidemiology, health technologies.
    keywords: countries; covid-19; data; health; human; impact; life; pandemic; people; rights; world
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        item: #299 of 7819
          id: cord-035142-axyjd96e
      author: Zein, Joe G.
       title: Safety of influenza vaccine during COVID-19
        date: 2020-09-17
       words: 284
      flesch: 14
     summary: Quantifying social distancing arising from pandemic influenza Association of use of angiotensin-converting enzyme inhibitors and angiotensin ii receptor blockers with testing positive for coronavirus disease 2019 (COVID-19) Addressing extreme propensity scores via the overlap weights The Guillain-Barre syndrome and the 1992-1993 and 1993-1994 influenza vaccines The potential role of Th17 immune responses in coronavirus immunopathology and vaccine-induced immune enhancement Association between seasonal influenza vaccination in 2008-2009 and pandemic influenza A (H1N1) 2009 infection among school students from Kobe Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness during Spring-Summer 2009: four observational studies from Canada Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection BMI stands for body mass index; USD for US dollar; COPD for chronic obstructive pulmonary disease; NSAIDS for nonsteroidal anti-inflammatory drugs; ACE for angiotensin-converting enzyme; ARB for angiotensin receptor blocker; and ICU for Intensive Care Unit Two unadjuvanted split virion, inactivated, quadrivalent influenza vaccines were provided to patients in 2019. However, based on our data, influenza vaccine is not associated with increased pandemic COVID-19 severity, providing reassurance that the vaccination strategy for global influenza should proceed as planned during the COVID-19 pandemic.
    keywords: influenza; pandemic
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        item: #300 of 7819
          id: cord-035176-oryjjoiw
      author: Detterline, Stephanie
       title: An internal medicine residency’s response to the COVID-19 crisis: caring for our residents while caring for our patients
        date: 2020-10-29
       words: 2446
      flesch: 46
     summary: Residents were asked to evaluate how well the residency addressed their well-being, communication, scheduling/staffing, preparing residents for clinical service, and education on a five-point Likert type scale (5-very well, 4-somewhat well, 3-neutral, 2-somewhat poorly, 1-very poorly). Residents evaluating our program as responding 'very well' or 'somewhat well' in each area evaluated were as follows: well-being needs (88%), effective communication (86%), scheduling/staffing (78%), preparing residents for clinical service (77%), educational needs (76%).
    keywords: covid-19; crisis; needs; program; residents; response
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        item: #301 of 7819
          id: cord-035210-s9t76pcz
      author: Kaye, Avi Gurion
       title: The efficacy of IL-6 inhibitor Tocilizumab in reducing severe COVID-19 mortality: a systematic review
        date: 2020-11-02
       words: 4899
      flesch: 36
     summary: TCZ patients in five studies had significant secondary bacteremia but one reported a lower rate than the SOC (Rojas-Marte et al., 2020). As virus binds ACE2, thus reducing its availability, there is an increase of angiotensin II in COVID-19 patients, creating a positive feedback loop that advances pro-inflammatory signaling (Gubernatorova et al., 2020) .
    keywords: covid-19; et al; il-6; mortality; patients; rate; studies; tcz; tocilizumab
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        item: #302 of 7819
          id: cord-035216-gdhz7mr4
      author: Li, Xiaoran
       title: Deep learning prediction of likelihood of ICU admission and mortality in COVID-19 patients using clinical variables
        date: 2020-11-06
       words: 3783
      flesch: 44
     summary: In risk score models, SPSS was used to cross-check statistical significance of the top features, in which all top features used in the final analysis of risk score model had a p < 0.001. Although we ranked all variables and explicitly listed 10 or 15 top variables, we built the predictive model and risk score model using only the top five variables to simplify and increase translation potential in the clinical settings.
    keywords: admission; data; icu; model; mortality; patients; risk; score; variables
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        item: #303 of 7819
          id: cord-035230-p999nlnc
      author: Nikopoulou, V. A.
       title: Mental Health Screening for COVID-19: a Proposed Cutoff Score for the Greek Version of the Fear of COVID-19 Scale (FCV-19S)
        date: 2020-11-10
       words: 4644
      flesch: 37
     summary: COVID-19 fear in Eastern Europe: validation of the Fear of COVID-19 Scale Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: A systematic review and meta-analysis with comparison to the COVID-19 pandemic Psychometric validation of the Bangla Fear of COVID-19 Scale: confirmatory factor analysis and Rasch analysis The Health Anxiety Inventory: development and validation of scales for the measurement of health anxiety and hypochondriasis Adaptation of the Fear of COVID-19 Scale: its association with psychological distress and life satisfaction in Turkey Public responses to the novel 2019 coronavirus (2019-nCoV) in Japan: mental health consequences and target populations SDQ: discriminative validity and diagnostic potential The 2-item Generalized Anxiety Disorder scale had high sensitivity and specificity for detecting GAD in primary care Validation and psychometric evaluation of the Italian version of the Fear of COVID-19 Scale Translation, adaptation and validation of instruments or scales for use in cross-cultural health care research: α clear and user-friendly guideline A brief measure for assessing generalized anxiety disorder: the GAD-7 The biology of fear-and anxiety-related behaviors Appealing to fear: a meta-analysis of fear appeal effectiveness and theories Life in a post-pandemic world: what to expect of anxiety-related conditions and their treatment Guidelines for developing, translating, and validating a questionnaire in perioperative and pain medicine Psychometric properties of the Greek version of FCV-19S WHO announces COVID-19 disease outbreak a pandemic Fear appeal theory Evaluation of the English version of the Fear of COVID-19 Scale and its relationship with behavior change and political beliefs World Medical Association Declaration of Helsinki. The short health anxiety inventory: psychometric properties and construct validity in a non-clinical sample The fear of COVID-19 scale: development and initial validation The short health anxiety inventory: a systematic review and meta-analysis Health anxiety: comparison of the latent structure in medical and non-medical samples Actitudes y temores ante la pandemia por COVID-19 en Argentina Psychometric evaluation of the Arabic version of the Fear of COVID-19 Scale Diagnostic and statistical manual of mental disorders The psychology of coronavirus fear: are healthcare professionals suffering from coronaphobia?
    keywords: anxiety; covid-19; cutoff; et al; fear; health; pandemic; scale
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        item: #304 of 7819
          id: cord-035269-60im90ab
      author: Khalaf, Ola Osama
       title: Coping with depression and anxiety in Egyptian physicians during COVID-19 pandemic
        date: 2020-11-11
       words: 2435
      flesch: 47
     summary: The BRCS score had a significantly negative correlation with the depression, anxiety, and stress scales of DASS (p = 0.018, 0.014, and 0.007 respectively). Female physicians were significantly higher in the depression, anxiety, and stress scales of DASS than male physicians (p = 0.001, < 0.001, and < 0.001, respectively).
    keywords: anxiety; depression; physicians; scale; stress
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        item: #305 of 7819
          id: cord-035272-j070oidg
      author: McGowan, Catherine R.
       title: COVID-19 testing acceptability and uptake amongst the Rohingya and host community in Camp 21, Teknaf, Bangladesh
        date: 2020-11-11
       words: 2020
      flesch: 46
     summary: On 11 June 2020, in response to low testing uptake, the Bangladesh Refugee Relief and Repatriation Commissioner (RRRC) decided to allow patients to return home while their test was being processed; however, uptake of testing for COVID-19 at the PHCC (and across all sentinel sites) remained low [3] . = 49.2 p = < 0.001 with patients offered a testing script more likely to consent to COVID-19 testing.
    keywords: covid-19; rohingya; testing
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        item: #306 of 7819
          id: cord-035275-lfyxbg92
      author: Servotte, Jean-Christophe
       title: Development and implementation of an end-of-shift clinical debriefing method for emergency departments during COVID-19
        date: 2020-11-11
       words: 4992
      flesch: 40
     summary: Clinical debriefings had a median duration of 10 min (IQR 7–13). After titles and abstracts were reviewed, 16 articles were found to report concepts and principles related to clinical debriefing.
    keywords: covid-19; debriefing; discover; facilitator; implementation; phase; program; shift; simulation; team
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        item: #307 of 7819
          id: cord-035285-dx5bbeqm
      author: Simmhan, Yogesh
       title: GoCoronaGo: Privacy Respecting Contact Tracing for COVID-19 Management
        date: 2020-11-11
       words: 13696
      flesch: 56
     summary: A review of contact tracing apps can be found in 11, 15, 19, 41 , and their features are contrasted in Table 1 . However, the global adoption of contact tracing apps is low.
    keywords: analytics; app; apps; backend; bluetooth; contact; covid-19; data; device; digital; gcg; gcg app; location; network; number; proximity; rssi; service; time; users
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        item: #308 of 7819
          id: cord-035290-ungilw9s
      author: Rice, Louis
       title: After Covid-19: urban design as spatial medicine
        date: 2020-11-11
       words: 2900
      flesch: 44
     summary: The role of architects and urban health planners in tackling key contemporary public health challenges Urban planning for healthy cities Responsive environments: A manual for designers The global economic burden of noncommunicable diseases Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19 Urban planning as an enabler of urban health: Challenges and good practice in England following the 2012 planning and public health reforms Public places, urban spaces: The dimensions of urban design Centre for Workforce Intelligence (CfWI) and the Royal Society for Public Health (RSPH) Department for Education. 2020. key: cord-035290-ungilw9s authors: Rice, Louis title: After Covid-19: urban design as spatial medicine date: 2020-11-11 journal: Urban Des Int DOI: 10.1057/s41289-020-00142-6 sha: doc_id: 35290 cord_uid: ungilw9s This article draws out key implications for urban designers from the Covid-19 pandemic, particularly the relation between urban design and health.
    keywords: covid-19; design; health; nature; urban; world
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        item: #309 of 7819
          id: cord-035307-r74ovkbd
      author: Liu, Shuchang
       title: Attitudes towards Wildlife Consumption inside and outside Hubei Province, China, in Relation to the SARS and COVID-19 Outbreaks
        date: 2020-11-11
       words: 4135
      flesch: 48
     summary: More than half of participants (≥53.5%) reported that they had stopped eating wildlife meat because most species of wildlife are legally protected. The virus may pass onto humans when they consume wildlife meat, and subsequently may lead to the risk of human-to-human transmission (Zhang et al. 2020) .
    keywords: covid-19; hubei; meat; outbreak; participants; sars; wildlife
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        item: #310 of 7819
          id: cord-035312-xh7oomcg
      author: Mandal, Amit K.J.
       title: In situ immune-mediated pulmonary artery thrombosis and Covid-19 pneumonitis
        date: 2020-11-11
       words: 786
      flesch: 31
     summary: Their findings demonstrated that in patients with Covid-19 and a clinical suspicion for pulmonary embolus (PE), more than one-third of computed tomography pulmonary angiogram (CTPA) studies were found positive for PE compared to the yield of inpatient CTPA prior to the pandemic at 12 to 17%. on their case series of 23 patients [2] which suggested that PE in Covid-19 patients was more likely to be located in the peripheral opacitated lung segments, suggesting local clot formation.
    keywords: covid-19; patients; pulmonary
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        item: #311 of 7819
          id: cord-035314-afngpddq
      author: Malik, Is-haq O
       title: Severe Acute Respiratory Syndrome Coronavirus 2 Induced Focal Segmental Glomerulosclerosis
        date: 2020-10-11
       words: 1914
      flesch: 37
     summary: Of all the variants, collapsing FSGS carries the worst prognosis Collapsing FSGS is associated with a more severe nephrotic syndrome and worse renal outcome than other variants of FSGS.
    keywords: covid-19; fsgs; infection; injury; kidney; patients
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        item: #312 of 7819
          id: cord-035315-j5mknuv5
      author: Rahim, Fawad
       title: Mortality of Patients With Severe COVID-19 in the Intensive Care Unit: An Observational Study From a Major COVID-19 Receiving Hospital
        date: 2020-10-12
       words: 2715
      flesch: 54
     summary: This necessitated determining the survival of COVID-19 patients in relation to comorbid conditions and ventilatory support in our population. The high mortality with IMV patients could be due to inadequate intensive care services and lack of enough experience with treating COVID-19 related acute respiratory distress syndrome.
    keywords: age; covid-19; icu; mortality; patients; study
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        item: #313 of 7819
          id: cord-035327-p2c6q1zj
      author: Segura de la Cal, Teresa
       title: Unexpected Favourable Course of Coronavirus Disease 2019 in Chronic Thromboembolic Pulmonary Hypertension Patients
        date: 2020-11-11
       words: 2533
      flesch: 35
     summary: As physicians, we were prepared for COVID-19 catastrophic outcomes in CTEPH patients, based on their tampered haemostasis, delicate cardiorespiratory balance and comorbidities. Therefore, reduced ACE2 expression would be expectable in CTEPH patients which may have contributed to reduce their initial viral load.
    keywords: case; cmh; covid-19; cteph; lung; patients; ventilation
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        item: #314 of 7819
          id: cord-035333-2duu1c9n
      author: MacLaren, Graeme
       title: What’s new in ECMO for COVID-19?
        date: 2020-11-12
       words: 1414
      flesch: 41
     summary: Data on 1035 patients with COVID-19 supported with ECMO showed an estimated cumulative incidence of in-hospital mortality 90 days after ECMO initiation of 37% (95% CI 34-40). Median PaO 2 /FiO 2 ratio prior to cannulation was 72 (IQR 59-94) and 60% had a trial of prone positioning prior to ECMO initiation.
    keywords: covid-19; ecmo; patients
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        item: #315 of 7819
          id: cord-035380-qfvskz9n
      author: Nasajpour, Mohammad
       title: Internet of Things for Current COVID-19 and Future Pandemics: an Exploratory Study
        date: 2020-11-12
       words: 7972
      flesch: 50
     summary: Using drones plays an important role during a quarantine to decrease the number of COVID-19 cases by lowering the interaction of healthcare workers with patients and contaminated areas. Coronavirus: Moscow rolls out patient-tracking app Selfie app' to keep track of quarantined poles Blockchain app used to track COVID-19 cases in Latin America Hong kong is using tracker wristbands to geofence people under coronavirus quarantine Israeli phone apps aim to track coronavirus, guard privacy IoT blockchain platform launches a COVID-19 contact tracing app Early detection is key to combating the spread of coronavirus 78.
    keywords: application; coronavirus; covid-19; devices; drone; healthcare; internet; iot; pandemic; patients; people; quarantine; robots; smartphone; things
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        item: #316 of 7819
          id: cord-035396-lg7m9xzs
      author: Bains, Amarpreet S.
       title: Maintaining Throughput and Reducing Discharge Delays After Increasing Capacity During The Covid-19 Pandemic: A New York City Hospital’s Experience
        date: 2020-11-12
       words: 2408
      flesch: 43
     summary: The average length of stay for Covid-19 patients who did require home oxygen was only 0.5 days longer than for those who did not: more than a 50% reduction in turnaround compared with our pre-pandemic timeframe for home oxygen setup. We attribute this improvement to: better communication between unit managers and discharge control center; earlier identification of barriers; on-site representative for home oxygen; streamlining of the documentation and authorization processes; providers learning how to optimize documentation; and time saved by many patients not requiring home delivery.
    keywords: covid-19; discharge; home; oxygen; pandemic; patients
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        item: #317 of 7819
          id: cord-035443-mkba8f1e
      author: Wong, Leslie P.
       title: COVID-19 and Elder Health Inequity in Dialysis
        date: 2020-11-13
       words: 623
      flesch: 36
     summary: NEJM Catalyst Caring for dialysis patients in a time of COVID-19 COVID-19 Infection Risk Among Hemodialysis Patients in Long-Term Care Facilities Mitigating Risk of COVID-19 in Dialysis Facilities Minimizing the Risk of COVID-19 Among Patients on Dialysis Playing the Cards We are Dealt: COVID-19 and Nursing Homes Characteristics of U.S. Nursing Homes with COVID-19 Cases Guidance for Infection Control and Prevention of Coronavirus Disease 2019 (COVID-19) in dialysis facilities Long-Term Care Policy after Covid-19 -Solving the Nursing Home Crisis Uncovering the Devaluation of Nursing Home Staff During COVID-19: Are We Fuelling the Next Health Care Crisis? Connected communities of care in times of crisis As the pandemic surfaced, dialysis facilities rapidly implemented new infection control protocols to screen, triage, and cohort patients based on symptoms and history of exposure to COVID-19.
    keywords: covid-19; dialysis; facilities
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        item: #318 of 7819
          id: cord-102281-xymfoa86
      author: Higuera, J
       title: Traqueostomía En Cuidados Intensivos En Pacientes Covid 19
        date: 2020-11-13
       words: 4028
      flesch: 46
     summary: La técnica se llevó a cabo con las medidas de protección frente al Covid 19 recomendadas, en la mayoría de ellas con control de la vía aérea mediante videolaringoscopia. Un aspecto importante a destacar en nuestra muestra es que todos los pacientes presentaban situación de distress respiratorio agudo grave, reflejado en el alto porcentaje de pacientes que requieren pronación y relajación previa a la realización de la traqueostomía, estando los pacientes comprometidos a nivel de la oxigenación y siendo de vital importancia el evitar complicaciones intraprocedimiento en forma de desturación,
    keywords: con; covid; del; las; los; mecánica; neumonía; pacientes; patients; por; que; realización; tracheostomy; traqueostomía; técnica; uci; una; ventilación
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        item: #319 of 7819
          id: cord-102456-6jt4ksha
      author: Taylor-Cousar, Jennifer L.
       title: How I Do It: Restarting Respiratory Clinical Research in the Era of the COVID19 Pandemic
        date: 2020-11-13
       words: 4070
      flesch: 27
     summary: The rapid deployment of these clinical tools has allowed their application to clinical research studies, and in some cases ensuring the continued conduct of study consent, safety visits and assessments, and collection of outcome measurements. Equally important, it is imperative that clinical research staff are protected from potential risks of contracting respiratory tract infections including SARS-CoV-2 from research subjects or individuals accompanying them.
    keywords: covid-19; data; pandemic; procedures; research; safety; sars; staff; study; testing
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        item: #320 of 7819
          id: cord-102557-25mu0mo9
      author: Torres-Salinas, Daniel
       title: Daily growth rate of scientific production on Covid-19. Analysis in databases and open access repositories
        date: 2020-04-14
       words: 2611
      flesch: 44
     summary: 2) Cuantificar del mismo modo el número de preprints diarios que se publican en los distintos repositorios y describir el fenómeno del acceso Abierto Los resultados que se alcacen en este trabajo no solo tienen un valor descriptivo de un fenómeno informativo singular, si no que nos permitirá a los profesionales de la información tener un mapa objetivo y global de aquellas de las fuentes de información y bases de datos más útiles para enfrentarnos al COVID-19 y asesorar a nuestros investigadores. Desde ese momento el número de publicaciones se duplica con un promedio de 15 días, como ocurrió entre el 14 de marzo y el 30 de marzo cuando se pasan de las 3041 publicaciones a las 6022.
    keywords: acceso; como; con; covid-19; datos; del; dimensions; las; los; por; publicaciones; pubmed; que; repositorios; sobre; una
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        item: #321 of 7819
          id: cord-102885-5y9nkal3
      author: Lee, Hyeon-Seung
       title: Deterioration of mental health despite successful control of the COVID-19 pandemic in South Korea.
        date: 2020-11-13
       words: 5322
      flesch: 45
     summary: key: cord-102885-5y9nkal3 authors: Lee, Hyeon-Seung; Dean, Derek; Baxter, Tatiana; Griffith, Taylor; Park, Sohee title: Deterioration of mental health despite successful control of the COVID-19 pandemic in South Korea. Thus, despite effective mitigation of the pandemic, there was a striking deterioration of mental health.
    keywords: covid-19; days; depression; health; korea; loneliness; pandemic; south
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        item: #322 of 7819
          id: cord-103214-3lz33pj3
      author: Kortuem, S. O.
       title: The Role of the Emergency Department in Protecting the Hospital as a Critical Infrastructure in the Corona Pandemic Strategies and Experiences of a Rural Sole Acute-Care Clinic
        date: 2020-09-09
       words: 4295
      flesch: 40
     summary: All confirmed COVID-19 cases were correctly identified in the structured pretriage, unprotected contacts with employees or other patients did not take place, nosocomial transmissions were not known. An essential strategic element was a very short-term restructuring of the Emergency Department with the objectives of reducing the number of cases within the clinic, detecting COVID-19 cases as sensitively as possible and separating the patient pathways at an early stage.
    keywords: cases; clinical; covid-19; department; emergency; hospital; patients; preprint; time
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        item: #323 of 7819
          id: cord-103533-k1lg8c7q
      author: Jin, C.
       title: Development and Evaluation of an AI System for COVID-19
        date: 2020-03-23
       words: 6437
      flesch: 49
     summary: In the open data set LIDC-IDRI and ILD-HUG, the false positive rates of AI system were 3.12% and 11.85%, and the system showed good generalization ability (Figure 7 c ). It is hard to notice the evidence of COVID-19 in these two cases, but AI system can still identify them.
    keywords: ai system; cases; cohort; covid-19; diagnosis; figure; license; medrxiv; preprint; system
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        item: #324 of 7819
          id: cord-103545-2v89ku4o
      author: Bellos, Ioannis
       title: Maternal and perinatal outcomes in pregnant women infected by SARS-CoV-2: A meta-analysis
        date: 2020-11-13
       words: 5205
      flesch: 38
     summary: First Case in Portugal Asymptomatic COVID-19 infection in late pregnancy indicated no vertical transmission Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy Clinical characteristics of 19 neonates born to mothers with COVID-19 Analysis of vaginal delivery outcomes among pregnant women in Wuhan, China during the COVID-19 pandemic Lack of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 Emergency cesarean section on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) confirmed patient Association of COVID-19 infection with pregnancy outcomes in healthcare workers and general women Mortality of a pregnant patient diagnosed with COVID-19: The rate of neonatal transmission did not differ between women with and without severe disease (OR: 1.94, 95% CI: 0.50-7.60).
    keywords: analysis; case; cov-2; covid-19; disease; infection; neonatal; sars; studies; transmission
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        item: #325 of 7819
          id: cord-103629-zhw8vh3e
      author: None
       title: cord-103629-zhw8vh3e
        date: None
       words: 1372
      flesch: 44
     summary: AI is not only helpful in the treatment of COVID-19 infected patients but also for their proper health monitoring. CT An analysis of pathology knowledge and decision making for the development of artificial intelligence-based consulting systems Contentious issues and evolving concepts in the clinical presentation and management of patients with COVID-19 infection with reference to use of therapeutic and other drugs used in Co-morbid diseases (Hypertension, diabetes etc.).
    keywords: covid-19; help; patients
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        item: #326 of 7819
          id: cord-103659-wpwfqhp2
      author: Almqvist, J.
       title: Neurological manifestations of coronavirus infections: a systematic review
        date: 2020-09-01
       words: 6079
      flesch: 36
     summary: The lancet Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study Dysregulation of immune response in patients with COVID-19 in Wuhan, China European Patients with mild-to-moderate Coronavirus Disease Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Olfactory Bulb Magnetic Resonance Imaging in SARS-CoV-2-Induced Anosmia: The First Report Early recovery following new onset anosmia during the COVID-19 pandemic-an observational cohort study Acute-onset smell and taste disorders in the context of Covid-19: a pilot multicenter PCR-based case-control study Patterns of smell recovery in 751 patients affected by the COVID-19 outbreak Persistent Symptoms in Patients After Acute COVID-19 The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings COVID-19 related neuroimaging findings: A signal of thromboembolic complications and a strong prognostic marker of poor patient outcome Cerebrovascular disease in patients with COVID-19: neuroimaging, histological and clinical description Imaging in Neurological Disease of Hospitalized COVID-19 Patients: An Italian Multicenter Retrospective Observational Study Risk of Ischemic Stroke in Patients With Coronavirus Disease 2019 (COVID-19) vs Patients With Influenza Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study.
    keywords: copyright; cov-2; funder; holder; license; medrxiv; patients; peer; preprint; review; sars; september
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        item: #327 of 7819
          id: cord-103899-6tqm99g1
      author: Mirzaei, Rasoul
       title: The emerging role of microRNAs in the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection
        date: 2020-11-13
       words: 9770
      flesch: 42
     summary: [121] Global Trends in Epidemiology of Coronavirus Disease 2019 (COVID-19) Virus against virus: a potential treatment for 2019-nCov (SARS-CoV-2) and other RNA viruses A realistic two-strain model for MERS-CoV infection uncovers the high risk for epidemic propagation Development of genetic diagnostic methods for novel coronavirus 2019 (nCoV-2019) in Japan How miRNAs can protect humans from coronaviruses COVID-19 Overview of the current promising approaches for the development of an effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine Clinical features of patients infected with 2019 novel coronavirus in Coronavirus disease 2019 (COVID-19): Immunological approaches and emerging pharmacologic treatments A novel coronavirus outbreak of global health concern Bacterial co-infections with SARS-CoV-2 COVID-19, SARS and MERS: are they closely related? Coronavirus disease (COVID-19) pandemic Exosome and exosomal microRNA: trafficking, sorting, and function Role of microRNAs in Staphylococcus aureus infection: Potential biomarkers and mechanism Role of microRNAs in the immune system, inflammation and cancer MicroRNAs and the immune response to respiratory virus infections Host Immune Response and Immunobiology of Human SARS-CoV-2 Infection The human immune system against Staphylococcus epidermidis Prevalence of atlE, ica, mecA, and mupA Genes in Staphylococcus epidermidis Isolates T cell-mediated immune response to respiratory coronaviruses Structural, glycosylation and antigenic variation between 2019 novel coronavirus (2019-nCoV) and SARS coronavirus (SARS-CoV) T cell responses to whole SARS coronavirus in humans Profile of specific antibodies to the SARS-associated coronavirus Recent Advances in the Vaccine Development Against Middle East Respiratory Syndrome-Coronavirus Vaccine-elicited CD8+ T cells protect against respiratory syncytial virus strain A2-line19F-induced pathogenesis in BALB/c mice Interferon interplay helps tissue cells to cope with SARS-coronavirus infection CD8+ T cells and macrophages regulate pathogenesis in a mouse model of Middle East respiratory syndrome Dysregulation of immune response in patients with COVID-19 in Immunopathology of SARS-CoV-2 infection: immune cells and mediators, prognostic factors, and immune-therapeutic implications A contemporary review on pathogenesis and immunity of COVID-19 infection In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients Pathological findings of COVID-19 associated with acute respiratory distress syndrome Cytokine storm induced by SARS-CoV-2 Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome COVID-19: consider cytokine storm syndromes and immunosuppression Pattern recognition receptors and inflammation Activation of airway epithelial cells by toll-like receptor agonists NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses Advances in microRNAs: implications for immunity and inflammatory diseases Expression and function of micro RNAs in immune cells during normal or disease state Integrating microRNAs into a system biology approach to acute lung injury miR-146a is critical for endotoxin-induced tolerance , regulates murine macrophage inflammatory responses Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium Retinoic acidinducible gene I-inducible miR-23b inhibits infections by minor group rhinoviruses through downregulation of the very low density lipoprotein receptor MicroRNAs: small RNAs with big effects MicroRNAs and immunity: novel players in the regulation of normal immune function and inflammation, Seminars in cancer biology Skare, miR-181a is an intrinsic modulator of T cell sensitivity and selection Expression profiling of human immune cell subsets identifies miRNA-mRNA regulatory relationships correlated with cell type specific expression An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes MicroRNA miR-155 affects antiviral effector and effector Memory CD8 T cell differentiation Micro-RNA 155 is required for optimal CD8+ T cell responses to acute viral and intracellular bacterial challenges Rosas-Taraco, microRNAs in viral acute respiratory infections: immune regulation, biomarkers, therapy, and vaccines A recently identified rhinovirus genotype is associated with severe respiratory-tract infection in children in Germany Structure of a human common cold virus and functional relationship to other picornaviruses Rhinovirus and dsRNA induce RIG-I-like receptors and expression of interferon β
    keywords: cells; coronavirus; cov-2; covid-19; expression; host; human; infection; mers; micrornas; mirnas; proteins; replication; responses; rsv; sars; study; target; virus
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        item: #328 of 7819
          id: cord-103929-5rnmyq3n
      author: Karsiyakali, Nejdet
       title: Evaluation of the Sexual Functioning of Individuals Living in Turkey during the COVID-19 Pandemic: An Internet-Based Nationwide Survey Study
        date: 2020-10-26
       words: 2983
      flesch: 42
     summary: In subgroup analyses, it was observed that there was a statistically significant difference between the groups for changing in the number of sexual intercourse, the number of masturbation, and sexual desire during the COVID-19 pandemic (p<0.05, for each). When the subgroups were compared in terms of sexual parameters, it was observed that there was a statistically significant difference between the groups for changing in the number of sexual intercourse, the number of masturbation, and sexual desire during the COVID-19 pandemic (p<0.05, for each) ( Table 3 ).
    keywords: covid-19; intercourse; pandemic; participants; study
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        item: #329 of 7819
          id: cord-104426-qz8pffei
      author: Tay, K
       title: COVID-19 in Singapore and Malaysia: Rising to the Challenges of Orthopaedic Practice in an Evolving Pandemic
        date: 2020-04-07
       words: 4521
      flesch: 44
     summary: Malays Orthop J DOI: nan sha: doc_id: 104426 cord_uid: qz8pffei With the increasing number of COVID-19 cases and related deaths worldwide, we decided to share the development of this condition in Singapore and Malaysia. The index imported COVID-19 case was diagnosed in Singapore on 23rd January 2020.
    keywords: cases; covid-19; health; hospitals; malaysia; management; medical; orthopaedic; patients; singapore; staff; ward
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        item: #330 of 7819
          id: cord-104440-9hbib8b3
      author: Kariyanna, Pramod Theetha
       title: Thrombus in Transit and Impending Pulmonary Embolism Detected on POCUS in a Patient with COVID-19 Pneumonia
        date: 2020-05-05
       words: 1319
      flesch: 37
     summary: medRxiv Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Venous thromboembolism in COVID-19 patients Pulmonary artery thrombosis in a patient with severe acute respiratory syndrome Diagnosis and pharmacotherapy of severe acute respiratory syndrome: what have we learnt? Severe Acute Respiratory Syndrome and Venous Thromboembolism in Multiple Organs Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Acute pulmonary embolism and COVID-19 pneumonia: a random association? Pulmonary thrombosis in 2019-nCoV pneumonia? In this report, we present the case of a 55-year-old man who presented with COVID-19 pneumonia, and was found to have a thrombus in transit by routine point of care ultrasound (POCUS).
    keywords: coronavirus; covid-19; pneumonia; transit
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        item: #331 of 7819
          id: cord-104441-zxxg8i1b
      author: Raoufi, Masoomeh
       title: Correlation between Chest Computed Tomography Scan Findings and Mortality of COVID-19 Cases; a Cross sectional Study
        date: 2020-05-14
       words: 2959
      flesch: 46
     summary: Cardiothoracic Imaging Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study The role of imaging in 2019 novel coronavirus pneumonia (COVID-19) Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan Frequency and distribution of chest radiographic findings in COVID-19 positive patients Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study COVID-19 pneumonia: a review of typical CT findings and differential diagnosis.
    keywords: cases; chest; covid-19; ctss; patients; scan
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        item: #332 of 7819
          id: cord-104454-qavbcwp7
      author: Amon, Joseph J.
       title: COVID-19 and Detention: Respecting Human Rights
        date: 2020-06-17
       words: 1169
      flesch: 48
     summary: Yet, more than three months since COVID-19 emerged, the US CDC lists guidance for schools, childcare centers, colleges, workplaces, faith-based organizations, community events, homeless shelters, healthcare professionals and retirement communities but not for jails, prisons, or immigration detention centers. In Spain, immigration authorities began releasing people held in immigration detention centers on March 18.
    keywords: centers; covid-19; detainees; detention
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        item: #333 of 7819
          id: cord-104461-nkqdkvfu
      author: Aujayeb, Avinash
       title: Consolidating medical ambulatory care services in the COVID-19 era
        date: 2020
       words: 1670
      flesch: 49
     summary: key: cord-104461-nkqdkvfu authors: Aujayeb, Avinash; Johnston, Robert; Routh, Charlotte; Wilson, Patricia; Mann, Sandra title: Consolidating medical ambulatory care services in the COVID-19 era date: 2020 journal: Int J Health Sci (Qassim) DOI: nan sha: doc_id: 104461 cord_uid: nkqdkvfu nan The current COVID-19 era poses challenges for reorganization of care, redistribution, and rationing of services. [3, 4] A wing for ambulatory care was purpose built for June 2019.
    keywords: ambulatory; care; covid-19; mac; patients; service
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        item: #334 of 7819
          id: cord-104467-elwfz1gk
      author: Kariyanna, Pramod Theetha
       title: A Systematic Review of COVID-19 and Myocarditis
        date: 2020-06-05
       words: 3524
      flesch: 50
     summary: This systematic review found that the majority of COVID-19 myocarditis patients had cardiomegaly, pleural effusion and reduced LVEF. COVID-19 myocarditis affected patients over the age of 50 and incidences among both genders were equally reported.
    keywords: acute; case; covid-19; myocarditis; patients; review; studies; study
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        item: #335 of 7819
          id: cord-104473-bx3svdrk
      author: Kariyanna, Pramod Theetha
       title: Utility of D-dimer as a Prognostic Factor in SARS CoV2 Infection: A Review
        date: 2020-06-22
       words: 2584
      flesch: 34
     summary: We will review the utility of D-dimer as screening tool and in the risk stratification of COVID-19 patients prone to developing thromboembolic events, DIC, immune dysregulation and death. More severe COVID-19 infection requiring hospitalization tends to present more often with elevated D-dimer, which continues to increase with disease severity, as seen in a study whereg hyper-fibrinolysis, reflected by elevated serum D-dimer levels, was present in 97% of COVID-19 patients at admission and increased further in all patients prior to death while decreasing to control levels in survivors or non-ARDS patients [34] .
    keywords: clinical; coronavirus; covid-19; dimer; mortality; patients
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        item: #336 of 7819
          id: cord-104486-syirijql
      author: Adiga, Aniruddha
       title: Data-driven modeling for different stages of pandemic response
        date: 2020-09-21
       words: 7181
      flesch: 39
     summary: As with any mathematical modeling effort, data plays a big role in the utility of such models. Similar to the importation risk, such models may provide an estimate of when cases may emerge in different parts of the country.
    keywords: case; contact; covid-19; data; datasets; disease; individuals; modeling; models; number; pandemic; response; spread; stages; time
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        item: #337 of 7819
          id: cord-104500-m0kfom0x
      author: Kyriakopoulos, Anthony M.
       title: The Potential Role of Super Spread Events in SARS-COV-2 Pandemic; a Narrative Review
        date: 2020-09-21
       words: 6850
      flesch: 31
     summary: Lessons from SARS epidemic taught us that the key to control is minimizing the time from the diagnosis of infection to prompt hospital isolation and diminishing the probability Table 3 : Key clinical and laboratory screening functions to appropriately forecast, prevent, and confront SARS! SARS epidemic taught us that control programs were inefficient in controlling the epidemic within a population, and failed to identify and provide a targeted infection diagnosis in groups causing potential SSEs (5, 17) .
    keywords: articles; coronavirus; cov-2; covid-19; disease; epidemic; hepatitis; human; infection; mers; potential; sars; sses; super; syndrome; transmission
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        item: #338 of 7819
          id: cord-104501-e5e0xrou
      author: Bashash, Davood
       title: The Prognostic Value of Thrombocytopenia in COVID-19 Patients; a Systematic Review and Meta-Analysis
        date: 2020-09-19
       words: 2758
      flesch: 37
     summary: A modern and pragmatic definition of Laboratory Medicine The critical role of laboratory medicine during coronavirus disease 2019 (COVID-19) and other viral outbreaks Abolghasemi H. Laboratory Findings in COVID-19 Diagnosis and Prognosis Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal Mechanism of thrombocytopenia in COVID-19 patients Exploring possible mechanisms for COVID-19 induced thrombocytopenia: Unanswered Questions Thrombocytopenia in patients with severe acute respiratory syndrome Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet respiratory medicine Summary of probable SARS cases with onset of illness from 1 November Middle East respiratory syndrome coronavirus (MERS-CoV) Real estimates of mortality following COVID-19 infection.
    keywords: analysis; covid-19; disease; patients; platelet; studies
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        item: #339 of 7819
          id: cord-104507-xx7t26rl
      author: Safari, Saeid
       title: Extracorporeal Hemoperfusion as a Potential Therapeutic Option for Severe COVID-19 patients; a Narrative Review
        date: 2020-08-22
       words: 3428
      flesch: 20
     summary: key: cord-104507-xx7t26rl authors: Safari, Saeid; Salimi, Alireza; Zali, Alireza; Jahangirifard, Alireza; Bastanhagh, Ehsan; Aminnejad, Reza; Dabbagh, Ali; Lotfi, Amir Hossein; Saeidi, Mohammad title: Extracorporeal Hemoperfusion as a Potential Therapeutic Option for Severe COVID-19 patients; a Narrative Review date: 2020-08-22 journal: In Italy, the formal recommendation is made by the Italy Brescia Renal COVID Task Force and a publication by the Italian Society of Nephrology and ERA-EDTA, to specifically use CytoSorb in severe COVID-19 patients with Stage 3 renal failure on continuous renal replacement therapy (CRRT) (50) .
    keywords: covid-19; cytokine; hemoperfusion; mediators; patients; shock; syndrome; therapy; treatment
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        item: #340 of 7819
          id: cord-104509-hxaq9bf5
      author: Khateri, Sorour
       title: The Prevalence of Underlying Diseases and Comorbidities in COVID-19 Patients; an Updated Systematic Review and Meta-analysis
        date: 2020-09-12
       words: 5327
      flesch: 49
     summary: A randomeffects model was applied for articles with high heterogeneity (I2>50%); for other cases, a fixed effects model was used. The pooled prevalence of shock in patients aged 60 years or less was 10% (95% Cl: 4 -17%; I2= 73.33%; Q test = 14.67; P = 0.001)
    keywords: acute; covid-19; disease; injury; kidney; patients; prevalence
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        item: #341 of 7819
          id: cord-117445-zu2mns82
      author: Gao, Jian
       title: Quantifying Policy Responses to a Global Emergency: Insights from the COVID-19 Pandemic
        date: 2020-06-24
       words: 7843
      flesch: 52
     summary: Within this corpus, we identify COVID-19 related policy documents through keyword filtering (7, 730 documents in total, see SI S1.1), allowing us to compare COVID-19 policy documents with all other policy documents published in 2020. We find that the shares of policy documents by three major field categories (Fig. S4A ) and individual fields (Fig. S4B) stay relatively stable over time, suggesting that the shifts are observed in COVID-19 policy documents only.
    keywords: attention; countries; country; covid-19; covid-19 policy; deaths; documents; fig; policy; policy documents; share
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        item: #342 of 7819
          id: cord-117800-jzokod4q
      author: Umer, Hamza
       title: Evaluating the Effectiveness of Regional Lockdown Policies in the Containment of Covid-19: Evidence from Pakistan
        date: 2020-06-04
       words: 3623
      flesch: 51
     summary: Overall, the world is divided regarding the use and effectiveness of lockdown policies. This article offers a systematic contribution to the aforementioned debate by examining the effectiveness of lockdown policies in the containment of Covid-19 in the context of Pakistan.
    keywords: cases; country; covid-19; lockdown; pakistan; regions; spread; virus
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        item: #343 of 7819
          id: cord-118214-jna34p8p
      author: Dhakal, Parashar
       title: IVACS: Intelligent Voice Assistant for Coronavirus Disease (COVID-19) Self-Assessment
        date: 2020-09-06
       words: 3195
      flesch: 51
     summary: Fig. 1 shows the overview of proposed IVACS architecture. During the experiment, the IVACS will interact with participants and guide them through the process upon knowing their health status.
    keywords: assistant; experiment; ivacs; participants; performance; self; user
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        item: #344 of 7819
          id: cord-118509-nws464ug
      author: Islam, Muhammad Nazrul
       title: A Survey on the Use of AI and ML for Fighting the COVID-19 Pandemic
        date: 2020-08-03
       words: 5215
      flesch: 43
     summary: Although AI research in healthcare is emerging, most of the research is concentrated on three diseases: cancer, neurology and cardiology. Several deep learning based research (48%) studies have used chest X-Ray and CT scan images to determine Only one cross-country research has been conducted with the purpose of sustainable development, where correlation among confirmed cases, environmental and demographic factors of four different countries were calculated and compared.
    keywords: articles; covid-19; data; images; learning; pandemic; patients; ray; research
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        item: #345 of 7819
          id: cord-118731-h5au2h09
      author: None
       title: cord-118731-h5au2h09
        date: None
       words: 7181
      flesch: 39
     summary: As with any mathematical modeling effort, data plays a big role in the utility of such models. Similar to the importation risk, such models may provide an estimate of when cases may emerge in different parts of the country.
    keywords: case; contact; covid-19; data; datasets; disease; individuals; modeling; models; number; pandemic; response; spread; stages; time
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        item: #346 of 7819
          id: cord-119104-9d421si9
      author: Huynh, Tin Van
       title: BANANA at WNUT-2020 Task 2: Identifying COVID-19 Information on Twitter by Combining Deep Learning and Transfer Learning Models
        date: 2020-09-06
       words: 1816
      flesch: 56
     summary: In the future, we will improve our model's performance by exploring different features of the users' tweets and transfer learning models with fine-tuning techniques. The ensemble model from our three transformer and deep learning models is used for the final prediction.
    keywords: covid-19; information; model; tweets
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        item: #347 of 7819
          id: cord-119275-2mhsp6jn
      author: Heidarian, Shahin
       title: CT-CAPS: Feature Extraction-based Automated Framework for COVID-19 Disease Identification from Chest CT Scans using Capsule Networks
        date: 2020-10-30
       words: 3643
      flesch: 45
     summary: In this study, a Capsule Network-based feature extractor is presented to detect specific characteristics of CT slices, followed by a Max Pooling Layer to convert slice-level feature maps into patientlevel ones. The CT-CAPS is trained on a dataset of CT slices labeled by three experienced radiologists [14] to determine slices demonstrating infection and slices without an evidence of infection.
    keywords: caps; chest; covid-19; infection; lung; model; slices
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        item: #348 of 7819
          id: cord-119307-rlc2f6zw
      author: Zhang, Edwin
       title: Covidex: Neural Ranking Models and Keyword Search Infrastructure for the COVID-19 Open Research Dataset
        date: 2020-07-14
       words: 4760
      flesch: 54
     summary: The training set contains approximately 500k pairs of query and relevant documents, where each query has one relevant passage on average; non-relevant documents for training are also provided as part of the training data. (2019) have both previously demonstrated that models trained on MS MARCO can be directly applied to other document ranking tasks.
    keywords: document; neural; query; ranking; results; round; runs; search; text
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        item: #349 of 7819
          id: cord-120442-qfgoue67
      author: Zaman, Anis
       title: The Relationship between Deteriorating Mental Health Conditions and Longitudinal Behavioral Changes in Google and YouTube Usages among College Students in the United States during COVID-19: Observational Study
        date: 2020-09-05
       words: 5880
      flesch: 42
     summary: On one hand, online engagements can cause fluctuations in mental health. It has been widely applied in researches involving social media and mental health.
    keywords: anxiety; behavior; covid-19; data; google; group; health; outbreak; pandemic; search; study; youtube
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        item: #350 of 7819
          id: cord-121285-4ni1vv4l
      author: Zhang, Han
       title: How Does COVID-19 impact Students with Disabilities/Health Concerns?
        date: 2020-05-11
       words: 6110
      flesch: 42
     summary: Students with disabilities/health concerns had higher marginalized status or vulnerabilities than students without in the study: 82.1% (23) are female, and 17.9% (5) male, 67.9% (19) are Asian, 39.3% (11) are first-generation college students, 21.4% (3) are LGBTQIA+ and the average SES is 5.5. Such students expressed considerable concern about the educational and financial impacts of COVID-19.
    keywords: concerns; covid-19; data; disabilities; education; health; health concerns; impact; stress; students
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        item: #351 of 7819
          id: cord-121777-3zrnz9nc
      author: Qian, Xuelin
       title: M3Lung-Sys: A Deep Learning System for Multi-Class Lung Pneumonia Screening from CT Imaging
        date: 2020-10-07
       words: 7585
      flesch: 44
     summary: Besides, patient-level classification network only has four layers, and takes a volume of CT slice features, instead of images as input, which are extracted by the former network, to output the patient-level labels (in Section III-C). Then, to recover the temporal information in CT sequence slices and enable CT volumes screening, we propose a patientlevel classification network, taking as input a volume of CT slice features extracted from the slice-level classification network.
    keywords: classification; covid-19; diagnosis; feature; learning; level; lung; multi; network; patient; pneumonia; slice; system
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        item: #352 of 7819
          id: cord-122159-sp6o6h31
      author: Raskar, Ramesh
       title: COVID-19 Contact-Tracing Mobile Apps: Evaluation and Assessment for Decision Makers
        date: 2020-06-04
       words: 6032
      flesch: 50
     summary: Implementation and mapping of fair information practices COVID-19 dashboard Recommendation regarding the use of cloth face coverings Singapore says it will make its contact tracing tech freely available to developers 31% can't pay the rent: 'It's only going to get worse Fair information practice principles Clever cryptography could protect privacy in COVID-19 contact tracing apps COVID-19 contact tracing privacy principles Centre for the Mathematical Modelling of Infectious Diseases COVID-19 Working Group 2019 coronavirus: The Korean clusters. Turning app data over to law enforcement or other non-health actors, such as commercial entities seeking to target ads to potential customers, threatens users' rights and privacy.
    keywords: app; apps; contact; covid-19; data; health; location; person; privacy; users
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        item: #353 of 7819
          id: cord-123714-1ll0a9q6
      author: Zhou, Jianlong
       title: Examination of community sentiment dynamics due to covid-19 pandemic: a case study from Australia
        date: 2020-06-22
       words: 4060
      flesch: 53
     summary: However, these previous work on COVID-19 sentiment analysis largely focuses on the public sentiment in country-level or globally for a specific period. In this study, sentiment of each LGA is aggregated with the Eq. 1 -3 to get the dominant mean sentiment of LGA, which is also called community sentiment: where s i p is the sentiment value of tweet i which has positive sentiment, n p is the number of tweets which have positive sentiment, where s i g is the sentiment value of tweet i which has negative sentiment, n g is the number of tweets which have negative sentiment, N is the number of all tweets in an LGA, and S f is the final sentiment of an LGA.
    keywords: analysis; community; covid-19; dynamics; period; sentiment; twitter
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        item: #354 of 7819
          id: cord-123970-qikmhoo4
      author: Bao, Forrest Sheng
       title: Triaging moderate COVID-19 and other viral pneumonias from routine blood tests
        date: 2020-05-13
       words: 7148
      flesch: 59
     summary: Machine learning is needed for the tasks above because blood test features have rather complicated relationships or correlations which will be missed and not made use of by simple thresholding on raw features, e.g., claiming that CRP>2.5 means COVID-19, otherwise non-COVID-19 viral pneumonia. Trained on blood data from 208 moderate COVID-19 subjects and 86 subjects with non-COVID-19 moderate viral pneumonia, the best result is obtained in an SVM-based classifier with an accuracy of 84%, a sensitivity of 88%, a specificity of 80%, and a precision of 92%.
    keywords: blood; classifier; covid-19; feature; node; non; pneumonia; samples; subjects; svm; svms; test
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        item: #355 of 7819
          id: cord-124618-51235tn2
      author: Said, Ahmed Ben
       title: Predicting COVID-19 cases using Bidirectional LSTM on multivariate time series
        date: 2020-09-10
       words: 2571
      flesch: 54
     summary: Conclusion: Using data of multiple countries in addition to lockdown measures improve accuracy of the forecast of daily cumulative COVID-19 cases. This yields a richer dataset for training COVID-19 cumulative cases prediction model per countries cluster.
    keywords: cases; covid-19; data; model; number; time
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        item: #356 of 7819
          id: cord-124654-zs2533s5
      author: Wei, Wenqi
       title: A Real-time Robot-based Auxiliary System for Risk Evaluation of COVID-19 Infection
        date: 2020-08-18
       words: 3782
      flesch: 51
     summary: The general procedure of our model is silence removal, feature extraction, cough detection, and cough classification. After detecting cough events, we build a cough classifier aiming to identify COVID-19 cough among events that reveals other respiratory disease.
    keywords: classification; cough; covid-19; detection; features; model; robot; system; time
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        item: #357 of 7819
          id: cord-125190-87wcp92x
      author: Xiong, Chenfeng
       title: Data-Driven Modeling Reveals the Impact of Stay-at-Home Orders on Human Mobility during the COVID-19 Pandemic in the U.S
        date: 2020-05-02
       words: 4362
      flesch: 47
     summary: 2) Interactions between stay-at-home order and state, to capture the varying effect of policies across different states; 3) Time-varying patterns, including an average changing pattern and a seasonally changing pattern (weekly patterns), to fit the autoregressive time series; 4) Spatiotemporal interactions, to capture the spatiotemporal heterogeneity over time across different states. We reorganized the mobility data and anchored the data to the dates when different states announced their Stay-at-home orders, and then quantified the human mobility changes, compared to the January benchmark, three weeks, two weeks, and one week before and after the orders were issued (illustrated in Figure 2 ).
    keywords: average; effects; home; mobility; number; orders; person; states; trips
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        item: #358 of 7819
          id: cord-127759-wpqdtdjs
      author: Qi, Xiao
       title: Chest X-ray Image Phase Features for Improved Diagnosis of COVID-19 Using Convolutional Neural Network
        date: 2020-11-06
       words: 3915
      flesch: 47
     summary: Although numerous studies have shown the capability of CNNs in effective identification of COVID-19 from CXR images, none of these studies investigated local phase CXR image features as multi-feature input to a CNN architecture for improved diagnosis of COVID-19 disease. In this study, we design a novel multi-feature convolutional neural network (CNN) architecture for multi-class improved classification of COVID-19 from CXR images.
    keywords: accuracy; covid-19; cxr; feature; fusion; images; multi
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        item: #359 of 7819
          id: cord-127860-9fngwsh3
      author: Reyad, Omar
       title: Novel Coronavirus COVID-19 Strike on Arab Countries and Territories: A Situation Report I
        date: 2020-03-20
       words: 1357
      flesch: 58
     summary: A novel coronavirus from patients with pneumonia in China Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, The Lancet Coronavirus COVID-19 Global Cases by the Coronavirus COVID-19 Global Cases by the Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modeling study Mass gathering events and reducing further global spread of COVID-19: a political and public health dilemma Health security capacities in the context of COVID-19 outbreak: an analysis of International Health Regulations annual report data from 182 countries COVID-19 in Italy: momentous decisions and many uncertainties The resilience of the Spanish health system against the COVID-19 pandemic Day Level Forecasting for Coronavirus Disease (COVID-19) Spread: Analysis, Modeling and Recommendations COVID-19): Among the countries with Coronavirus in the Arab world, Qatar has the highest number of Coronavirus cases, followed by Bahrain and Saudi Arabia as shown in Table I and Figure 2 .
    keywords: coronavirus; countries; covid-19
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        item: #360 of 7819
          id: cord-128991-mb91j2zs
      author: Agapiou, Sergios
       title: Modeling of Covid-19 Pandemic in Cyprus
        date: 2020-10-05
       words: 7458
      flesch: 52
     summary: Implementation of joint maximum likelihood estimation of model parameters and outlier sizes. Figure Data and code are available at GitHub (https://github.com/chrisnic12/covid_cyprus) Detecting multiple generalized change-points by isolating single ones Remdesivir for the treatment of Covid-19 -preliminary report Bayesian Theory Real time Bayesian estimation of the epidemic potential of emerging infectious diseases Statistical Fraud Detection: A Review Joint estimation of model parameters and outlier effects in time series Generalized SEIR epidemic model (fitting and computation) A New Framework and Software to Estimate Time-Varying Reproduction Numbers During Epidemics The species severe acute respiratory syndrome-related coronavirus: classifying 2019-ncov and naming it sars-cov-2 Statistical analysis of time series: Some recent developments Impact of non-pharmaceutical interventions (NPI)s to reduce COVID-19 mortality and healthcare demand Statistical Analysis of Count Time Series Models: A GLM perspective Log-linear Poisson autoregression An mrna vaccine against sars-cov-2 -preliminary report Inference for single and multiple change-points in time series Regression Models for Time Series Analysis Modeling infectious diseases in humans and animals A contribution to the mathematical theory of epidemics Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (sars-cov-2) tscount: An R package for analysis of count time series following generalized linear models Generalized Linear Models Hand-hygiene mitigation strategies against global disease spreading through the air transportation network Circular binary segmentation for the analysis of array-based DNA copy number data Epidemic analysis of COVID-19 in China by dynamical modeling Monte Carlo statistical methods Adaptive trend estimation in financial time series via multiscale change-pointinduced basis recovery Estimating the dimension of a model The metric we need to manage COVID-19 rt: The effective reproduction number Coronavirus disease (COVID-19) -situation report-197 Estimating the number of change-points via Schwarz' criterion A novel coronavirus from patients with pneumonia in China
    keywords: analysis; cases; covid-19; cyprus; data; model; number; rate; time
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        item: #361 of 7819
          id: cord-129728-fpoqjmes
      author: Ouyang, Xi
       title: Dual-Sampling Attention Network for Diagnosis of COVID-19 from Community Acquired Pneumonia
        date: 2020-05-06
       words: 6611
      flesch: 51
     summary: To illustrate it, we use an established VB-Net toolkit [10] to automatically segment lungs and pneumonia infection regions on all the cases in our training-validation (TV) set (with details of our TV set provided in Section IV), and show the distribution of the ratios between the infection regions and lungs in Fig. 1 . We propose a dual-sampling strategy to train the network, which further alleviates the imbalanced distribution of the sizes of pneumonia infection regions.
    keywords: attention; cap; covid-19; diagnosis; images; infection; network; pneumonia; regions; rn34; sampling
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        item: #362 of 7819
          id: cord-130351-w9mij6c6
      author: Mamidala, Estari
       title: In silico identification of clinically approved medicines against the main protease of SARS-CoV-2, causative agent of covid-19
        date: 2020-04-25
       words: 2683
      flesch: 44
     summary: Among the 47 approved drugs, 2 drugs are anti-H1N1 drugs, 4 are anti-TB drugs, 24 are anti-HIV-1 drugs and 17 are anti-malarial drugs are selected from PubChem database. Docking studies revealed that drug Oseltamivir (anti-H1N1 drug), Rifampin (anti-TB drug), Maraviroc, Etravirine, Indinavir, Rilpivirine (anti-HIV drugs) and Atovaquone, Quinidine, Halofantrine, Amodiaquine, Tetracylcine, Azithromycin, hydroxycholoroquine (anti-malarial drugs) among others binds in the active site of the protease with similar or higher affinity.
    keywords: anti; cov-2; covid-19; docking; drugs; protease; sars
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        item: #363 of 7819
          id: cord-131094-1zz8rd3h
      author: Parisi, L.
       title: QReLU and m-QReLU: Two novel quantum activation functions to aid medical diagnostics
        date: 2020-10-15
       words: 7577
      flesch: 36
     summary: Furthermore, it is worth noting the proposed quantum AFs led to improved classification outcomes as compared to recent advances in ReLU AFs, such as CReLU and VLReLU: • QReLU led to ACC, precision, sensitivity/recall, and F1-score all higher by 1% those obtained via CReLU when evaluating the CNN's classification performance on the MNIST data (Table 2 ). key: cord-131094-1zz8rd3h authors: Parisi, L.; Neagu, D.; Ma, R.; Campean, F. title: QReLU and m-QReLU: Two novel quantum activation functions to aid medical diagnostics date: 2020-10-15 journal: nan DOI: nan sha: doc_id: 131094 cord_uid: 1zz8rd3h The ReLU activation function (AF) has been extensively applied in deep neural networks, in particular Convolutional Neural Networks (CNN), for image classification despite its unresolved dying ReLU problem, which poses challenges to reliable applications.
    keywords: afs; benchmark; classification; cnn; dataset; qrelu; quantum; spiral; table
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        item: #364 of 7819
          id: cord-131975-9z3skg4n
      author: Senapati, Abhishek
       title: Impact of intervention on the spread of COVID-19 in India: A model based study
        date: 2020-04-10
       words: 4616
      flesch: 53
     summary: We plot the number of new COVID-19 cases (per day) in x−axis versus the cumulative number of COVID-19 cases (per day) in y − axis. We assume that the rate of disease transmission from asymptomatic individuals to susceptible individuals is less than that of from symptomatic individuals.
    keywords: cases; disease; intervention; model; number; period; time
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        item: #365 of 7819
          id: cord-132051-pb4ppdlm
      author: Cai, Yong
       title: The 2020 Sturgis Motorcycle Rally and COVID-19
        date: 2020-09-05
       words: 1849
      flesch: 59
     summary: Our baseline estimate suggests a one standard deviation increase in Sturgis attendance increased COVID-19 case growth by 1.1pp in the weeks after the rally. A synthetic control study on President Trump's political rally in Tulsa, Oklahoma on June 20, 2020 also found no effect on COVID-19 case growth (Dave, Friedson, Matsuzawa, McNichols, Redpath, Sabia, 2020) .
    keywords: covid-19; growth; rally; sturgis
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        item: #366 of 7819
          id: cord-132120-u5s5heqm
      author: Dempsey, Walter
       title: The Hypothesis of Testing: Paradoxes arising out of reported coronavirus case-counts
        date: 2020-05-21
       words: 8196
      flesch: 60
     summary: Measurement error data quality adjustment: relative frequency f 1 /f 0 In this setting, however, the difference in error terms is unlikely to be zero.
    keywords: bias; data; error; measurement; population; prevalence; rate; selection; testing
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        item: #367 of 7819
          id: cord-133143-ws708tsc
      author: Xu, Wentao
       title: Characterizing the roles of bots during the COVID-19 infodemic on Twitter
        date: 2020-11-12
       words: 4677
      flesch: 54
     summary: In this manner, we classified users into five types-credible humans, non-credible humans, credible bots, non-credible bots and other. We used different colors to represent credible and non-credible bots; red nodes are non-credible bots, green nodes are credible bots, and purple nodes are others that can be humans or unlabeled bots.
    keywords: bots; conspiracy; covid-19; humans; infodemic; misinformation; retweet; topic; users
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        item: #368 of 7819
          id: cord-133998-yni5wnwq
      author: Lee, Myeong
       title: Human Mobility during COVID-19 in the Context of Mild Social Distancing: Implications for Technological Interventions
        date: 2020-06-28
       words: 11818
      flesch: 49
     summary: Answering research questions is scientifically meaningful because it can show mobility pattern changes that are different from or similar to countries with different social distancing measures. Because human mobility patterns depend on the characteristics of the Voronoi cells, mobility needs to be understood by land-use.
    keywords: cells; city; covid-19; data; distancing; fig; korea; mobility; pandemic; panic; patterns; people; q q; socio; south; time; use; work
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        item: #369 of 7819
          id: cord-135296-qv7pacau
      author: Polsinelli, Matteo
       title: A Light CNN for detecting COVID-19 from CT scans of the chest
        date: 2020-04-24
       words: 3836
      flesch: 53
     summary: Deep Learning has been extensively used in medical imaging and convolutional neural networks (CNNs) have been also used for classification of CT images. Moreover, a large number of CT images have to be evaluated in a very short time thus increasing the probability of misclassifications.
    keywords: accuracy; cnn; covid-19; dataset; images; training
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        item: #370 of 7819
          id: cord-135363-l2r6uprq
      author: Bolsover, Gillian
       title: Balancing freedoms, rights and responsibilities during COVID in US: a study of anti- and pro-restriction discourse
        date: 2020-08-21
       words: 7234
      flesch: 43
     summary: Much more so than social or economic restrictions, ideas of political restrictions to fight COVID or the impact of social restrictions on political activity are an important issue that deserves much greater attention. This is important not just around the issue of economic restrictions where discussions of balance have tended to centre but even more importantly around social restrictions and discussions of individual vs. community rights and the rights and freedoms an individual gains as a member of a community.
    keywords: activity; covid; freedoms; individual; lockdown; posts; restrictions; rights; support; trends
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        item: #371 of 7819
          id: cord-136138-baxmoutj
      author: Hobson, Stacy
       title: Trust and Transparency in Contact Tracing Applications
        date: 2020-06-19
       words: 6466
      flesch: 37
     summary: Contact tracing applications use various techniques to identify exposure or contact events, and use sensitive personal data like some of the examples previously identified. We apply one of the recent transparent reporting techniques in the context of contact tracing applications.
    keywords: applications; contact; data; details; device; health; location; people; questions; spread; use
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        item: #372 of 7819
          id: cord-137263-mbww0yyt
      author: Hayashi, Teruaki
       title: Data Requests and Scenarios for Data Design of Unobserved Events in Corona-related Confusion Using TEEDA
        date: 2020-09-08
       words: 4370
      flesch: 54
     summary: Using TEEDA, we collect data items (data requests and providable data) in the corona-related confusion in the workshop, discuss the characteristics of missing data, and create three scenarios for data design of unobserved events focusing on variables. In Section 2, we explain the methodology of TEEDA based on the descriptions of data requests and providable data, as well as demonstrate the functions of the platform.
    keywords: confusion; corona; data; requests; types; users; variables
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        item: #373 of 7819
          id: cord-138439-wvynetna
      author: Wei, Xiyi
       title: Sex Differences in Severity and Mortality Among Patients With COVID-19: Evidence from Pooled Literature Analysis and Insights from Integrated Bioinformatic Analysis
        date: 2020-03-30
       words: 4729
      flesch: 42
     summary: Leung et al, 68 showed that in SARS patients, men were more likely to experience adverse events. 75 Anterior studies have reported that the high expression of ACE2 receptor in idiosyncratic organs of SARS patients pertains to the corresponding specific organ failure.
    keywords: ace2; analysis; cases; clinical; coronavirus; covid-19; data; male; patients; sars; sex; studies
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        item: #374 of 7819
          id: cord-138473-cajdh1z1
      author: Mobiny, Aryan
       title: Radiologist-Level COVID-19 Detection Using CT Scans with Detail-Oriented Capsule Networks
        date: 2020-04-16
       words: 7885
      flesch: 44
     summary: [28] proposed a 3D multi-conditional GAN (3D MCGAN) which uses context and nodule discriminators with distinct loss functions to generate realistic and diverse nodules in CT images. pneumonia Rapid ai development cycle for the coronavirus (covid-19) pandemic: Initial results for automated detection & patient monitoring using deep learning ct image analysis Radiologist-level pneumonia detection on chest x-rays with deep learning A large chest radiograph dataset with uncertainty labels Radiologist-Level COVID-19 Detection Using CT Scans with Detail-Oriented Capsule Networks 11 and expert comparison Radnet: Radiologist level accuracy using deep learning for hemorrhage detection in ct scans Automation of reading of radiological features from magnetic resonance images (mri's) of the lumbar spine without human intervention is comparable with an expert radiologist (issls prizebioengineering science): 56 Deep residual learning for image recognition Covid-19 image data collection Dynamic routing between capsules Matrix capsules with EM routing Videocapsulenet: A simplified network for action detection Fast capsnet for lung cancer screening Automated classification of apoptosis in phase contrast microscopy using capsule network Sparse unsupervised capsules generalize better Ct-realistic lung nodule simulation from 3d conditional generative adversarial networks for robust lung segmentation Synthesizing diverse lung nodules wherever massively: 3d multi-conditional gan-based ct image augmentation for object detection Dermgan: Synthetic generation of clinical skin images with pathology Star-caps: Capsule networks with straight-through attentive routing Stacked capsule autoencoders Learning multi-attention convolutional neural network for fine-grained image recognition Hide-and-seek: Forcing a network to be meticulous for weakly-supervised object and action localization Image-to-image translation with conditional adversarial networks Unet: Convolutional networks for biomedical image segmentation Rethinking the inception architecture for computer vision Densely connected convolutional networks How will country-based mitigation measures influence the course of the covid-19 epidemic?
    keywords: architecture; capsule; cases; classification; classifier; covid-19; data; decaps; image; information; network; radiologists
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        item: #375 of 7819
          id: cord-138965-pcmpc5sd
      author: Afzal, Shehzad
       title: A Visual Analytics Based Decision Making Environment for COVID-19 Modeling and Visualization
        date: 2020-10-22
       words: 3738
      flesch: 39
     summary: To facilitate the task requirements to compare the impact of different decision measures applied on certain combination of spatial regions at different points in time, we will extend the decision history visualization and navigation tool [4] with a support for thumbnails-based visual comparison linked with nodes that represent decision measures. This environment facilitates users to explore spatiotemporal model simulation data relevant to COVID-19 through a geospatial map with linked statistical views, apply different decision measures at different points in time, and understand their potential impact.
    keywords: analytics; covid-19; decision; measures; model; spread; time
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        item: #376 of 7819
          id: cord-138978-hfmgc5ve
      author: Venigalla, Akhila Sri Manasa
       title: Mood of India During Covid-19 -- An Interactive Web Portal Based on Emotion Analysis of Twitter Data
        date: 2020-05-06
       words: 4510
      flesch: 55
     summary: It has been observed that negative emotion tweets are observed in areas having more number of cases reported [Medford, Saleh, Sumarsono, Perl, and Lehmann (2020) ]. It has been observed that the sudden outrages of such pandemics affect public emotion and result in either constructive or destructive behavioural changes [Hou, Du, Jiang, Zhou, and Lin (2020) ].
    keywords: country; covid-19; emotions; india; number; state; tweets; twitter
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        item: #377 of 7819
          id: cord-140679-r6exuzxs
      author: Calderon-Ramirez, Saul
       title: Correcting Data Imbalance for Semi-Supervised Covid-19 Detection Using X-ray Chest Images
        date: 2020-08-19
       words: 7228
      flesch: 51
     summary: The application of deep learning for image classification of chest X-ray images of Covid-19 patients, could become a novel pre-diagnostic detection methodology. Additionally, a new dataset is included among thetested datasets, composed of chest X-ray images of Costa Rican adult patients Coronavirus is an endemic kind of virus that affects vertebrate animals, ranging from mammals to reptiles and birds.
    keywords: accuracy; chest; covid-19; data; dataset; images; imbalance; learning; mixmatch; model; observations; ray; work
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        item: #378 of 7819
          id: cord-140847-d6w8fu3b
      author: Venigalla, Akhila Sri Manasa
       title: SurviveCovid-19 -- A Game for Improving Awareness of Social Distancing and Health Measures for Covid-19 Pandemic
        date: 2020-04-21
       words: 4081
      flesch: 57
     summary: The younger generation of the present day spend a lot of time with their mobile phones, on various mobile apps and mobile games [Chan, Kow, and Cheng (2017) ]. A mario style based mobile game, Diabetic mario, was introduced to help in understanding ways to manage diabetes
    keywords: awareness; covid-19; et al; game; health; mobile; public
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        item: #379 of 7819
          id: cord-141541-g5pt10yn
      author: McLachlan, Scott
       title: Bluetooth Smartphone Apps: Are they the most private and effective solution for COVID-19 contact tracing?
        date: 2020-05-08
       words: 10545
      flesch: 42
     summary: As considerations move from dealing with the worst of the disease to containment of any remaining pockets of infection, much noise is being made in the media concerning the need to implement contact tracing apps (CTA) before the world can return ostensibly to normal (Mathews, 2020; Scott, 2020; Whittaker, 2020; Drew 2020) . key: cord-141541-g5pt10yn authors: McLachlan, Scott; Lucas, Peter; Dube, Kudakwashe; Hitman, Graham A; Osman, Magda; Kyrimi, Evangelia; Neil, Martin; Fenton, Norman E title: Bluetooth Smartphone Apps: Are they the most private and effective solution for COVID-19 contact tracing? date: 2020-05-08 journal: nan DOI: nan sha: doc_id: 141541 cord_uid: g5pt10yn Many digital solutions mainly involving Bluetooth technology are being proposed for Contact Tracing Apps (CTA) to reduce the spread of COVID-19.
    keywords: app; contact; covid-19; cta; data; device; disease; et al; infected; information; metadata; model; nhs; people; privacy; server; smartphone; solutions; user
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        item: #380 of 7819
          id: cord-142894-jrkqfl9p
      author: Bandt, Christoph
       title: Transparent Covid-19 prediction
        date: 2020-04-08
       words: 3612
      flesch: 69
     summary: The decrease of W t in Austria is fast, as for Chinese provinces with small infection numbers in Figure 2 . Figure 2 shows the development of weekly infection numbers W t in Hubei with capital Wuhan, four other Chinese provinces, South Korea, and Japan.
    keywords: covid-19; days; infection; time; weeks
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        item: #381 of 7819
          id: cord-143246-f97v2cih
      author: Paul, Aneesh Mathews
       title: Multifaceted COVID-19 Outbreak
        date: 2020-08-26
       words: 6065
      flesch: 58
     summary: Contesting Religion in Secularized Western European Countries India: Infections, Islamophobia, and Intensifying Societal Polarization New Center for Public Integrity/Ipsos Poll finds most Americans say the Coronavirus Pandemic is a Natural Disaster StatCa of Increase in Anti-Asian Sentiment, Attacks COVID-19 and Religious Congregations: Implications for Spread of Novel Pathogens Religion and the COVID-19 Pandemic God and COVID-19 Public Health Response to the Initiation and Spread of Pandemic COVID-19 in the United States High COVID-19 Attack Rate Among Attendees at Events at a Church-Arkansas Have Prayers Changed in Lockdown? A lot of literature exists in COVID-19, but most of them talk about the social and psychological side of the COVID problems.
    keywords: countries; covid-19; education; effects; home; india; learning; life; lockdown; pandemic; people; students; system; world
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        item: #382 of 7819
          id: cord-144221-ohorip57
      author: Kapoor, Mudit
       title: Authoritarian Governments Appear to Manipulate COVID Data
        date: 2020-07-19
       words: 3202
      flesch: 52
     summary: Aggregated data on Covd-19 across all countries in each of 4 regime categories provides further visual evidence that there is less variation in case data in authoritarian regimes. Figure 3 presents the results of our analysis for cumulative case and death data when our screening criteria is that growth in the 7 day centered moving average is greater than 7.5%.
    keywords: cases; covid-19; data; deaths; democracy; law
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        item: #383 of 7819
          id: cord-144860-a4i9vnjz
      author: Nason, Guy P.
       title: Rapidly evaluating lockdown strategies using spectral analysis: the cycles behind new daily COVID-19 cases and what happens after lockdown
        date: 2020-04-16
       words: 3907
      flesch: 55
     summary: The nonparametric nature of our analysis also permits us to split case time series at a boundary (e.g. lockdown or other intervention) and analyse the two halves separately, still with very short series in each. Hence, we transform our number of daily cases series to reveal the spectral dynamics.
    keywords: cases; countries; daily; days; lockdown; series
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        item: #384 of 7819
          id: cord-145906-4vgbzcx8
      author: Chae, Seo Yoon
       title: Estimation of Infection Rate and Prediction of Initial Infected Individuals of COVID-19
        date: 2020-04-27
       words: 1430
      flesch: 59
     summary: When we predict the evolution of the disease by some model, we required to use the confirmed data set such as the active cases, recovered cases, and death cases. We propose the parameters included in the dynamic equations and the initial number of infecting cases which is sum of the officially known cases and the unknown population of the asymptomatic cases.
    keywords: cases; covid-19; model
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        item: #385 of 7819
          id: cord-147282-6a1dfzs8
      author: Bermudi, Patricia Marques Moralejo
       title: Spatiotemporal dynamic of COVID-19 mortality in the city of Sao Paulo, Brazil: shifting the high risk from the best to the worst socio-economic conditions
        date: 2020-08-05
       words: 5982
      flesch: 43
     summary: Thus, the increase of one unit in the socioeconomic indicator represented a 25% reduction in the risk of dying from COVID-19, for the model using confirmed deaths, and a 33% reduction in the risk of dying, for the model using COVID-19 total deaths. Deaths from COVID-19, caused by the novel coronavirus of the severe acute respiratory syndrome (SARS-CoV-2), are considered avoidable because some collective and individual measures can prevent infection and because appropriate health assistance greatly reduces death risks.
    keywords: city; covid-19; covid-19 deaths; deaths; mortality; paulo; risk; socio; total
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        item: #386 of 7819
          id: cord-147853-h9t7sp4z
      author: Stephany, Fabian
       title: The CoRisk-Index: A data-mining approach to identify industry-specific risk assessments related to COVID-19 in real-time
        date: 2020-03-27
       words: 7703
      flesch: 46
     summary: Moreover, we discuss the assessment of economic risks via reports such as the 10-K reports required by the U. S. Securities and Exchange Commission (SEC). We examine company risk reports filed to the U.S. Securities and Exchange Commission (SEC).
    keywords: corona; covid-19; crisis; data; economy; industries; industry; reports; risk; sectors; stock; time; topics
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        item: #387 of 7819
          id: cord-148145-qg5623s7
      author: Singh, Bikash Chandra
       title: COVID-19 Pandemic Outbreak in the Subcontinent: A data-driven analysis
        date: 2020-08-22
       words: 5840
      flesch: 51
     summary: In order to find the transmission potential in the subcontinent, we used five models, namely, SIR model, Exponential growth, Sequential Bayesian method, Maximum likelihood estimation, and Time-dependent estimation, briefly described in what follows. We observe that the number of cases (black dotted line as shown in Figure 3A and in Figure 3B ) follows the number of confirmed cases expected (black line as shown in Figure 3A and Figure 3B ) by SIR model.
    keywords: bangladesh; cases; covid-19; model; number; sir; time
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        item: #388 of 7819
          id: cord-150218-javbnjrg
      author: Gupta, Prateek
       title: COVI-AgentSim: an Agent-based Model for Evaluating Methods of Digital Contact Tracing
        date: 2020-10-30
       words: 13390
      flesch: 50
     summary: We verify by comparing to real data that COVI-AgentSim is able to reproduce realistic COVID-19 spread dynamics, and perform a sensitivity analysis to verify that the relative performance of contact tracing methods are consistent across a range of settings. We present a formal description of this risk estimator in Appendix I. In this section we seek to provide following evidence: (1) our simulator is producing a reasonable approximation of real-world COVID-19 dynamics, and (2) it is a reliable testbed for comparing contact tracing methods.
    keywords: agent; bct; contact; covid-19; dalys; day; dct; disease; fct; individual; level; methods; model; number; population; risk; test; tracing; use; work
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        item: #389 of 7819
          id: cord-151118-25cbus1m
      author: Murray, Benjamin
       title: Accessible Data Curation and Analytics for International-Scale Citizen Science Datasets
        date: 2020-11-02
       words: 4954
      flesch: 54
     summary: Categorical fields Categorical fields map a limited set of string values to a corresponding numeric value. ExeTera's merging API allows the user to think in a tabular fashion by accepting tuples of ExeTera fields, which only load their contents when specifically requested.
    keywords: covid; data; dataset; exetera; fields; format; scale; study; symptom; test
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        item: #390 of 7819
          id: cord-151667-nz26lxyk
      author: Born, Jannis
       title: Accelerating COVID-19 Differential Diagnosis with Explainable Ultrasound Image Analysis
        date: 2020-09-13
       words: 5993
      flesch: 45
     summary: We combined our approach with the only available related work, lung US segmentation models from Roy et al. Figure 7a and Figure 7b show that COVID-19 is predicted better than healthy lung images, but not as distinct as pneumonia infections.
    keywords: cam; class; covid-19; data; diagnosis; images; lung; model; pneumonia; ultrasound; vgg
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        item: #391 of 7819
          id: cord-152238-z0gysxni
      author: Aronna, M. Soledad
       title: A model for COVID-19 with isolation, quarantine and testing as control measures
        date: 2020-05-15
       words: 8890
      flesch: 53
     summary: From the expression of $mathcal{R}_0$ and the simulations we conclude that isolation (social distancing) and testing among asymptomatic cases are fundamental actions to control the epidemic, {and the stricter these measures are and the sooner they are implemented,} the more lives can be saved. From the expression of R 0 and the simulations, we conclude that isolation (social distancing) and testing among asymptomatic cases are fundamental actions to control the epidemic, and the stricter these measures are and the sooner they are implemented, the more lives can be saved.
    keywords: cases; isolation; model; number; population; rate; testing; time
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        item: #392 of 7819
          id: cord-152740-ln2dbqn2
      author: Najafi, Ali
       title: ComStreamClust: A communicative text clustering approach to topic detection in streaming data
        date: 2020-10-11
       words: 4505
      flesch: 60
     summary: Having a set of topic clusters, the task is to assign a newly arrived tweet to one of the clusters. To better understand the effects of topic number per timeslot on the final performance, we created new experiments, the results of which are portrayed in Figure 3 .
    keywords: clustering; clusters; data; detection; number; topic; tweets; twitter
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        item: #393 of 7819
          id: cord-152881-k1hx1m61
      author: Toda, Alexis Akira
       title: Susceptible-Infected-Recovered (SIR) Dynamics of COVID-19 and Economic Impact
        date: 2020-03-25
       words: 4656
      flesch: 63
     summary: Figure 5 shows the dynamics of SIR model when (β, γ) = (0.2, 0.1), y 0 = 10 −6 , 10 −5 , 10 −4 , and z 0 Figure 5 : Dynamics of SIR model when (β, γ) = (0.2, 0.1), y 0
    keywords: epidemic; model; rate
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        item: #394 of 7819
          id: cord-153150-rep51ly9
      author: Tang, Chen
       title: Functional data analysis: An application to COVID-19 data in the United States
        date: 2020-09-17
       words: 7811
      flesch: 56
     summary: When the data are functions Some tools for functional data analysis Applied Functional Data Analysis: Methods and Case Studies fda: Functional Data Analysis A plug-in bandwidth selection procedure for longrun covariance estimation with stationary functional time series An optimal selection of regression variables Thinning-based models in the analysis of integer-valued time series: a review A survey of functional principal component analysis Forecasting intraday S&P 500 index returns: A functional time series approach Bootstrap methods for stationary functional time series Intraday forecasts of a volatility index: functional time series methods with dynamic updating Epidemiology and clinical features of COVID-19: A review of current literature Who belongs in the family? Applications of functional data analysis: a systematic review Functional data analysis Functional singular component analysis Functional data analysis for sparse longitudinal data Functional quadratic regression From sparse to dense functional data and beyond Meta-analysis of several epidemic characteristics of COVID-19 The authors would like to thank Drs. key: cord-153150-rep51ly9 authors: Tang, Chen; Wang, Tiandong; Zhang, Panpan title: Functional data analysis: An application to COVID-19 data in the United States date: 2020-09-17 journal: nan DOI: nan sha: doc_id: 153150 cord_uid: rep51ly9 The COVID-19 pandemic so far has caused huge negative impacts on different areas all over the world, and the United States (US) is one of the most affected countries.
    keywords: analysis; cases; covid-19; data; fts; method; number; period; states; study; time
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        item: #395 of 7819
          id: cord-154091-uuupn82y
      author: Xu, Zhanwei
       title: GASNet: Weakly-supervised Framework for COVID-19 Lesion Segmentation
        date: 2020-10-19
       words: 6368
      flesch: 51
     summary: [27] propose modules named Parallel Partial Decoder and Reverse Attention Module to improve lesion segmentation performance. GASNet is optimized to segment the lesion areas of a COVID-19 CT by the segmenter, and to replace the abnormal appearance with a generated normal appearance by the generator, so that the restored CT volumes are indistinguishable from healthy CT volumes by the discriminator.
    keywords: covid-19; dataset; gasnet; lesion; level; performance; segmentation; training; volume; voxel
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        item: #396 of 7819
          id: cord-154587-qbmm5st9
      author: Nguyen, Thanh Thi
       title: Artificial Intelligence in the Battle against Coronavirus (COVID-19): A Survey and Future Research Directions
        date: 2020-07-30
       words: 8188
      flesch: 38
     summary: -Imbalanced datasets due to insufficient COVID-19 medical image data. A summary of COVID-19 related data sources that are available for research purposes is also presented.
    keywords: applications; artificial; cases; coronavirus; covid-19; data; detection; images; intelligence; language; learning; machine; methods; model; number; pandemic; pneumonia; text; time
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        item: #397 of 7819
          id: cord-155530-fz9l7rc7
      author: Pierson, Emma
       title: Assessing racial inequality in COVID-19 testing with Bayesian threshold tests
        date: 2020-11-02
       words: 2784
      flesch: 50
     summary: We conclude by discussing broader applications of threshold tests in medicine. Threshold tests attempt to in-0% 20% 40% Probability of having COVID-19 Group 1 Risk Group 2 Risk Threshold Figure 2 : Hypothetical example illustrating that if two racial groups (red and blue lines) have very different distributions of COVID-19 risk, the same testing threshold produces different distributions above the threshold, and therefore different positivity rates.
    keywords: covid-19; model; positivity; race; rate; tests
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        item: #398 of 7819
          id: cord-155804-ft2pbgsl
      author: Yamac, Mehmet
       title: Convolutional Sparse Support Estimator Based Covid-19 Recognition from X-ray Images
        date: 2020-05-08
       words: 6028
      flesch: 47
     summary: Covid-19 chest X-ray images were gathered from different publicly available but scattered image sources. Accordingly, there are several recent works [6] , [7] , [8] , [9] that have been proposed for Covid-19 detection/ classification from X-ray images.
    keywords: classification; covid-19; csen; dictionary; images; learning; ray; recognition; representation; support; training
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        item: #399 of 7819
          id: cord-158252-l43ztxsl
      author: Pawlowski, Colin
       title: Longitudinal laboratory testing tied to PCR diagnostics in COVID-19 patients reveals temporal evolution of distinctive coagulopathy signatures
        date: 2020-05-21
       words: 6131
      flesch: 30
     summary: During each time window, we then compared the distribution of results from COVIDpos versus COVIDneg patients, allowing us to identify any lab tests which were significantly altered in COVIDpos patients during any time of disease acquisition, onset, and/or progression. With respect to erythrocytes, we found that both COVIDpos and COVIDneg patients developed a worsening mild anemia after PCR testing, but the trajectory was actually slower for COVIDpos patients (Figures 1B, 1H, Table 1 ).
    keywords: cohort; covid-19; covidneg; covidpos; diagnosis; lab; patients; platelet; test; testing; time
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        item: #400 of 7819
          id: cord-158545-qp5aemzw
      author: Stier, Andrew J.
       title: COVID-19 attack rate increases with city size
        date: 2020-03-23
       words: 2530
      flesch: 48
     summary: with city size, we expect larger cities to be more susceptible to both contagious diseases, but also to the spread of information (see below). Here, we estimate the growth rates and reproductive numbers of COVID-19 in US cities from March 14th through March 19th to reveal a power-law scaling relationship to city population size.
    keywords: cities; outbreak; population; rate
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        item: #401 of 7819
          id: cord-159554-50077dgk
      author: Shan, Fei
       title: Lung Infection Quantification of COVID-19 in CT Images with Deep Learning
        date: 2020-03-10
       words: 3548
      flesch: 44
     summary: However, it is a labor-intensive work for radiologists to annotate hundreds of COVID-19 CT scans. In order to provide delineation for hundreds of the training COVID-19 CT images, which is a tedious and time-consuming work, we proposed a human-in-the-loop (HITL) strategy to iteratively generate the training samples.
    keywords: covid-19; infection; lung; patients; scans; segmentation; system
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        item: #402 of 7819
          id: cord-160526-27kmder5
      author: Meyer, R. Daniel
       title: Statistical Issues and Recommendations for Clinical Trials Conducted During the COVID-19 Pandemic
        date: 2020-05-21
       words: 9272
      flesch: 36
     summary: Its effects on trial data create multiple potential statistical issues. Statistical analyses of trial data will then be properly adjusted for pandemic effects.
    keywords: analyses; covid-19; data; ices; missingness; need; pandemic; participants; strategy; study; treatment; trial
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        item: #403 of 7819
          id: cord-162772-5jgqgoet
      author: Viguerie, Alex
       title: Simulating the spread of COVID-19 via spatially-resolved susceptible-exposed-infected-recovered-deceased (SEIRD) model with heterogeneous diffusion
        date: 2020-05-11
       words: 3168
      flesch: 43
     summary: Incubation period of 2019 novel coronavirus (2019-CoV) infections among travelers from Wuhan, China Serial interval of COVID-19 among publicly reported confirmed cases The Ensemble Kalman Filter Impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand Spread and dynamics of the COVID-19 epidemic in Italy: Effects of emergency containment measures Modelling the COVID-19 epidemic and implementation of population-wide interventions in Italy Partial differential equations in ecology: spatial interactions and population dynamics Numerical simulation of a suceptible-exposed-infectious spacecontinuous model for the spread of rabies in raccoons across a realistic landscape Modeling the dynamics of novel coronavirus (2019-nCov) with fractional derivative Galerkin methods for a model of population dynamics with nonlinear diffusion A numerical method for spatial diffusion in age-structured populations Postitive RT-PCR test results in patients recovered from COVID-19 Serial interval of novel coronavirus (COVID-19) infections COVID-19 and Italy: what next? We plan to consider non-constant model parameters and adaptively update them according to measured data using dataassimilation procedures [4] .
    keywords: covid-19; data; dynamics; model; outbreak; population
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        item: #404 of 7819
          id: cord-164374-d3zojh1g
      author: Chowdhury, Aritra
       title: Symbolic Semantic Segmentation and Interpretation of COVID-19 Lung Infections in Chest CT volumes based on Emergent Languages
        date: 2020-08-22
       words: 4584
      flesch: 46
     summary: We augment existing state of the art semantic segmentation architectures with our symbolic generator to form symbolic segmentation models. The role of chest imaging in patient management during the covid-19 pandemic: a multinational consensus statement from the fleischner society Explainable artificial intelligence: Understanding, visualizing and interpreting deep learning models Towards emergent language symbolic semantic segmentation and model interpretability Towards semantic action analysis via emergent language Grad-cam: Visual explanations from deep networks via gradient-based localization Improved protein structure prediction using potentials from deep learning An automated lung segmentation approach using bidirectional chain codes to improve nodule detection accuracy Fast, portable tests come online to curb coronavirus pandemic Review of artificial intelligence techniques in imaging data acquisition, segmentation and diagnosis for covid-19 Large-scale screening of covid-19 from community acquired pneumonia using infection size-aware classification Computer analysis of computed tomography scans of the lung: a survey Severity assessment of coronavirus disease 2019 (covid-19) using quantitative features from chest ct images A survey of semantic segmentation Evaluating pseudo-r 2's for binary probit models A novel coronavirus outbreak of global health concern A deep learning algorithm using ct images to screen for corona virus disease Central focused convolutional neural networks: Developing a data-driven model for lung nodule segmentation Jcs: An explainable covid-19 diagnosis system by joint classification and segmentation Chest ct manifestations of new coronavirus disease 2019 (covid-19): a pictorial review Unet++: A nested u-net architecture for medical image segmentation, in: Deep Learning in Medical Image Analysis and Multimodal Learning for Clinical Decision Support
    keywords: covid-19; emergent; et al; infections; language; learning; lung; segmentation
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        item: #405 of 7819
          id: cord-167889-um3djluz
      author: Chen, Jianguo
       title: A Survey on Applications of Artificial Intelligence in Fighting Against COVID-19
        date: 2020-07-04
       words: 12258
      flesch: 46
     summary: The radiological signs of COVID-19 CXR images include airspace opacity, GGO, and later mergers. The architecture of the COVID-19 outbreak prediction model based on AI models is shown in Fig.
    keywords: cases; classification; coronavirus; cov-2; covid-19; cxr; data; deep; detection; disease; drug; et al; features; images; learning; lung; methods; model; patients; potential; prediction; protein; sars; sequences; website
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        item: #406 of 7819
          id: cord-168557-xt4bf31r
      author: Yi, Jirong
       title: Optimal Pooling Matrix Design for Group Testing with Dilution (Row Degree) Constraints
        date: 2020-08-05
       words: 1410
      flesch: 58
     summary: Pooled sample testing has been proposed as a method for increasing the effective capacity of existing testing infrastructure using the classical method of group testing or newly introduced compressed sensing techniques for virus testing [5] [6] [7] [8] [9] key: cord-168557-xt4bf31r authors: Yi, Jirong; Cho, Myung; Wu, Xiaodong; Mudumbai, Raghu; Xu, Weiyu title: Optimal Pooling Matrix Design for Group Testing with Dilution (Row Degree) Constraints date: 2020-08-05 journal: nan DOI: nan sha: doc_id: 168557 cord_uid: xt4bf31r In this paper, we consider the problem of designing optimal pooling matrix for group testing (for example, for COVID-19 virus testing) with the constraint that no more than $r>0$ samples can be pooled together, which we calldilution constraint.
    keywords: matrix; testing
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        item: #407 of 7819
          id: cord-168579-w2lsg7go
      author: Lee, Minha
       title: Human Mobility Trends during the COVID-19 Pandemic in the United States
        date: 2020-05-04
       words: 3910
      flesch: 48
     summary: [24] [25] Technology companies have presented insights on mobility trends by exploiting location data as well. Realizing the urgent needs on understanding mobility trends amid the pandemic, as one of the pioneering big data-driven studies on COVID-19, we aim to quantify changes in human mobility to provide tangible and intuitive evidence on individual and governmental efforts to migrate the spread.
    keywords: covid-19; data; distancing; home; mobility; pandemic; public; states
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        item: #408 of 7819
          id: cord-168710-a5pst4gf
      author: Jalilian, Abdollah
       title: A hierarchical spatio-temporal model to analyze relative risk variations of COVID-19: a focus on Spain, Italy and Germany
        date: 2020-09-28
       words: 4579
      flesch: 49
     summary: Gayawan et al. (2020) used a zero-inflated Poisson model for the daily number of new COVID-19 cases in the African continent and found that the pandemic varies geographically across Africa with notable high incidence in neighboring countries. Let Y it denote the number of new COVID-19 cases in region
    keywords: cases; covid-19; data; model; number; spain
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        item: #409 of 7819
          id: cord-168974-w80gndka
      author: Ozkaya, Umut
       title: Coronavirus (COVID-19) Classification using Deep Features Fusion and Ranking Technique
        date: 2020-04-07
       words: 3588
      flesch: 57
     summary: Convolution neural network layers use a matrix parameter with a matrix parameter that includes a different kinds of link between each input unit and each output unit. Convolution neural networks has some layer such as convolution, ReLU, Pooling, normalization, fully connected and softmax layer.
    keywords: convolution; covid-19; features; images; learning; method; networks
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        item: #410 of 7819
          id: cord-169141-71qh6yjr
      author: Krieg, Steven J.
       title: Pandemic Pulse: Unraveling and Modeling Social Signals during the COVID-19 Pandemic
        date: 2020-06-10
       words: 2077
      flesch: 52
     summary: Media Bias Data We used two independent sources for labeling the political bias of news sources: Media Bias/Fact Check (MBFC) and AllSides. MBFC is an independent online media outlet that evaluates news sources on their political bias and the factuality of their publications [8].
    keywords: bias; covid-19; data; news; sources
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        item: #411 of 7819
          id: cord-169484-mjtlhh5e
      author: Pellert, Max
       title: Dashboard of sentiment in Austrian social media during COVID-19
        date: 2020-06-19
       words: 4673
      flesch: 52
     summary: We adapt the dictionaries to the task at hand by excluding most obvious terms that can bias the analysis, as done in recent research validating Twitter word frequency data [18] . The sentiment dynamics on social media platforms can be influenced by content that spreads fear and other negative emotions.
    keywords: austria; covid-19; dashboard; data; derstandard.at; livetickers; online; platform; posts; public; twitter
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        item: #412 of 7819
          id: cord-170666-zjwlmzj3
      author: Liu, Shinan
       title: Characterizing Service Provider Response to the COVID-19 Pandemic in the United States
        date: 2020-11-01
       words: 5181
      flesch: 53
     summary: Considering an expected surge around the dates when states issued stayat-home orders or declared states of emergency, we seek to observe possible changes in the latency and throughput of network traffic across locations. Another paper used network traffic to determine campus occupancy at the effect of COVID-19 related policies on three campus populations across Singapore and the United States [24] .
    keywords: capacity; changes; covid-19; internet; isps; latency; network; providers; states; traffic
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        item: #413 of 7819
          id: cord-171089-z4oya6kz
      author: Liu, Meijun
       title: Can pandemics transform scientific novelty? Evidence from COVID-19
        date: 2020-09-26
       words: 9635
      flesch: 38
     summary: We examine the association between monthly change in scientific novelty, parachuting collaboration ratio and international collaboration of coronavirus papers by 50 sampled countries and their status as a confirmed COVID-19 infection site from January 2018 to April 2020 by month. This study investigates the relationship between the country-level monthly change in scientific novelty regarding entity combination of coronavirus papers and the occurrence of the first COVID-19 case in the country in a given month from January 2018 to April 2020.
    keywords: case; collaboration; countries; country; covid-19; entities; entity; month; novelty; novelty score; papers; parachuting collaboration; research
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        item: #414 of 7819
          id: cord-171231-m54moffr
      author: Habli, Ibrahim
       title: Enhancing Covid-19 Decision-Making by Creating an Assurance Case for Simulation Models
        date: 2020-05-17
       words: 2234
      flesch: 40
     summary: We argue that any COVID-19 simulation model that is used to guide critical policy decisions would benefit from being supported with such a case to explain how, and to what extent, the evidence from the simulation can be relied on to substantiate policy conclusions. However, a recent systematic review of 31 diagnostic and prediction models for COVID-19 concluded that, at present, none of these models could be recommended for practical use to inform critical policy decisions [2] .
    keywords: argument; evidence; models; policy; safety
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        item: #415 of 7819
          id: cord-171660-iqgi1906
      author: Yin, Hui
       title: Detecting Topic and Sentiment Dynamics Due to COVID-19 Pandemic Using Social Media
        date: 2020-07-05
       words: 3445
      flesch: 53
     summary: In most days, the number of positive sentiment tweets is slightly higher than negative sentiment tweets. The overall sentimental polarity was positive, but topic sentiment polarity various from topic to topic.
    keywords: covid-19; media; people; polarity; sentiment; topic; tweets
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        item: #416 of 7819
          id: cord-171703-n22tr8f2
      author: Hanmo, Li
       title: Robust estimation of SARS-CoV-2 epidemic at US counties
        date: 2020-10-22
       words: 13242
      flesch: 54
     summary: = β i, j (t)I i, j (t)/N i, j , which quantifies the risk of a susceptible individual in county j from state i to catch SARS-CoV-2 on day t. Here the risk is in an average sense among all susceptible individuals in a region. The studies of prevalence of SARS-CoV-2 antibodies based on serology tests 14 can be used to determine the size of population that have contracted SARS-CoV-2, and thus provides estimates on death rate, as the death toll is observed.
    keywords: cov-2; covid-19; death; model; number; sars; toll; transmission
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        item: #417 of 7819
          id: cord-171868-315udu9w
      author: Hussein, Molla Rashied
       title: Overview of digital health surveillance system during COVID-19 pandemic: public health issues and misapprehensions
        date: 2020-07-27
       words: 1371
      flesch: 46
     summary: Nonetheless, misuse or erroneous employment of public health data can be fatal and cannot be robust overnight. Social media can augment education and communication regarding public health, Singapore government has signed an agreement with WhatsApp to transmit precise COVID-19 information, and government initiatives to citizens.
    keywords: covid-19; data; health; privacy; system
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        item: #418 of 7819
          id: cord-172814-rywu0xp5
      author: Chen, M. Keith
       title: Causal Estimation of Stay-at-Home Orders on SARS-CoV-2 Transmission
        date: 2020-05-11
       words: 3797
      flesch: 41
     summary: These include any time-invariant individual demographics that both directly affect measured movement and sort individuals into counties with different policies (e.g., education, income), county-level characteristics ′ correlated with aggregate movement and COVID levels (e.g., population density), any regional time trends that effect both local movement and county distancing policies (e.g. spring break in costal FL), and any national time trends ′ that correlate with both movement and COVID levels (e.g. changes in national testing guidelines). To mitigate the severity of the ongoing COVID pandemic, governments have launched a range of social distancing policies including, by early April, mandatory stay-at-home orders (SHOs) in forty-five U.S. states and the District of Columbia.
    keywords: county; distancing; home; level; movement; orders; policies; transmission
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        item: #419 of 7819
          id: cord-173774-idj19hd3
      author: Li, Jinfeng
       title: COVID-19 Contact-tracing Apps: a Survey on the Global Deployment and Challenges
        date: 2020-05-07
       words: 1672
      flesch: 49
     summary: The Telegraph The UK's coronavirus contacts-tracing app explained NHSX differs with Apple and Google over contact-tracing app Without Apple and Google, the UK's contact-tracing app is in trouble Google ban use of location tracking in contact tracing apps Mobile applications to support contact tracing in the EU's fight against COVID-19 Guidelines 04/2020 on the use of location data and contact tracing tools in the context of the COVID-19 outbreak The coronavirus contact tracing privacy debate kicks up another gear Apple and Google partner on COVID-19 contact tracing technology framework [20] (yet to be released in May) -privacy-preserving contact tracing, Bluetooth based, decentralised, free of GPS.
    keywords: apps; contact; covid-19; data
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        item: #420 of 7819
          id: cord-174036-b3frnfr7
      author: Thomas, Loring J.
       title: Spatial Heterogeneity Can Lead to Substantial Local Variations in COVID-19 Timing and Severity
        date: 2020-05-20
       words: 6667
      flesch: 40
     summary: To model networks of potential contacts at scale, we employ spatial network models (19) , which are both computationally tractable and able to capture the effects of geography and population heterogeneity on network structure (20) . We also present chloropleth maps showing spatial variation in peak infection times, as well as the correlations between the infection trajectory within local areal units and the aggregate infection trajectory for the city as a whole.
    keywords: city; covid-19; days; diffusion; disease; heterogeneity; individuals; infection; models; network; time
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        item: #421 of 7819
          id: cord-175085-nmuxnf7k
      author: Mehrotra, Sanjay
       title: A Model of Supply-Chain Decisions for Resource Sharing with an Application to Ventilator Allocation to Combat COVID-19
        date: 2020-04-03
       words: 4543
      flesch: 51
     summary: The problem of estimating mechanical ventilator demand in the United States during an influenza pandemic was considered in [23] . In the context of ventilator allocation, a conceptual framework for allocating ventilators in a public emergency is proposed in [31] .
    keywords: covid-19; demand; model; patients; ventilators
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        item: #422 of 7819
          id: cord-175149-pwntqqtd
      author: Oniani, David
       title: A Qualitative Evaluation of Language Models on Automatic Question-Answering for COVID-19
        date: 2020-06-19
       words: 4955
      flesch: 52
     summary: Although our work has demonstrated the feasiblity of using language models for automatically answering COVID-19 questions, much can be done in the further research. Models from the BERT family showed the best performance in automatically answering COVID-19 questions, with BERT slightly outperforming BioBERT (4.225 vs. 4.100 -average scores) being the best.
    keywords: answer; bert; chatbot; covid-19; language; model; question; responses; sentences; similarity
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        item: #423 of 7819
          id: cord-176481-12ny6l5a
      author: Burridge, Henry C.
       title: Airborne infection R-numbers for regularly attended spaces: COVID-19 a case-study
        date: 2020-09-07
       words: 5267
      flesch: 44
     summary: Under these restrictive assumptions the classical Wells-Riley equation is recovered, namely that the likelihood, P , that infection spreads within a given indoor space during a time interval T is 2 A model for airborne infection risk in transient spaces with variable occupancy and activity levels The insightful work of Rudnick & Milton (2003) solved many of these challenges in assessing airborne infection risk and forms the basis for the modelling described in §2.
    keywords: air; infection; rate; risk; space; ventilation
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        item: #424 of 7819
          id: cord-176636-wzuhnfwp
      author: Malhotra, Aakarsh
       title: Multi-Task Driven Explainable Diagnosis of COVID-19 using Chest X-ray Images
        date: 2020-08-03
       words: 5070
      flesch: 53
     summary: Automatic detection from x-ray images utilizing transfer learning with convolutional neural networks Mo-bilenetv2: Inverted residuals and linear bottlenecks Automatic detection of coronavirus disease (covid-19) using x-ray images and deep convolutional neural networks Deep residual learning for image recognition Rethinking the inception architecture for computer vision Inception-v4, inception-resnet and the impact of residual connections on learning Covid-19 image data collection Chest X-Ray Images (Pneumonia) Classification of COVID-19 in chest X-ray images using DeTraC deep convolutional neural network Imagenet classification with deep convolutional neural networks Predicting covid-19 pneumonia severity on chest x-ray with deep learning Deep learning covid-19 features on cxr using limited training data sets CovidAID: COVID-19 Detection Using Chest X-Ray Densely Connected Convolutional Networks Deepcovidexplainer: Explainable covid-19 predictions based on chest x-ray images Estimating uncertainty and interpretability in deep learning for coronavirus (COVID-19) detection Identity mappings in deep residual networks Within the Lack of Chest COVID-19 X-ray Dataset: A Novel Detection Model Based on GAN and Deep Transfer Learning Covid-19 screening on chest x-ray images using deep learning based anomaly detection Covid-net: A tailored deep convolutional neural network design for detection of covid-19 cases from chest radiography images Segnet: The problem of small sample size of COVID-19 chest X-ray images was tackled by Loey et al.
    keywords: chest; classification; cmtnet; covid-19; disease; images; lung; ray; segmentation
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        item: #425 of 7819
          id: cord-177001-ron8oqrn
      author: Afshordi, Niayesh
       title: Diverse local epidemics reveal the distinct effects of population density, demographics, climate, depletion of susceptibles, and intervention in the first wave of COVID-19 in the United States
        date: 2020-07-01
       words: 9985
      flesch: 37
     summary: key: cord-177001-ron8oqrn authors: Afshordi, Niayesh; Holder, Benjamin; Bahrami, Mohammad; Lichtblau, Daniel title: Diverse local epidemics reveal the distinct effects of population density, demographics, climate, depletion of susceptibles, and intervention in the first wave of COVID-19 in the United States date: 2020-07-01 journal: nan DOI: nan sha: doc_id: 177001 cord_uid: ron8oqrn The SARS-CoV-2 pandemic has caused significant mortality and morbidity worldwide, sparing almost no community. We consider the entire set of local epidemics in the United States; a broad selection of demographic, population density, and climate factors; and local mobility data, tracking social distancing interventions, to determine the key factors driving the spread and containment of the virus.
    keywords: counties; covid-19; density; epidemic; et al; figure; growth; infection; mobility; model; mortality; population; population density; rate; time
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        item: #426 of 7819
          id: cord-177610-8aodvgww
      author: Groza, Adrian
       title: Detecting fake news for the new coronavirus by reasoning on the Covid-19 ontology
        date: 2020-04-26
       words: 3497
      flesch: 56
     summary: The information that hand dryers are effective is modeled with the role hasQuality from the Dolce ontology: dul : hasQuality(hand dryers 1 , e f f ective) ( Note also that the instance e f f ective is related to the instance situation 1 with the role involves: boxing : involves(situation 1 , e f f ective) ( The instance kill 1 is identified as an instance of the Kill 42030000 verb from the VerbNet and also as an instance of the Event concept from the Dolce ontology: Here the concept New is identified as a subclass of the Quality concept from Dolce. Here, C and D represent concept descriptions, while r is a role name.
    keywords: concept; coronavirus; covid-19; fred; information; instance; knowledge; ontology
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        item: #427 of 7819
          id: cord-178783-894gkrsk
      author: Zhang, Rui
       title: Drug Repurposing for COVID-19 via Knowledge Graph Completion
        date: 2020-10-19
       words: 8191
      flesch: 39
     summary: The potential of recent advances in artificial intelligence (AI) and machine learning for COVID-19 drug repurposing has also been highlighted [14] and several studies using these techniques have reported promising results [15] [16] [20, 21] ap-proach for COVID-19 drug repurposing.
    keywords: approach; completion; covid-19; data; discovery; drug; graph; inhibits; knowledge; literature; methods; models; network; patterns; protein; relations; repurposing
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        item: #428 of 7819
          id: cord-179749-qdbmpi7j
      author: Sacks, Daniel W.
       title: What can we learn about SARS-CoV-2 prevalence from testing and hospital data?
        date: 2020-08-01
       words: 10737
      flesch: 51
     summary: In practice we find that the lower bound is always higher in the non-COVID hospitalization sub-population than in the general population, so in practice this assumption implies that the lower bound on population prevalence is the confirmed positive rate among non-COVID hospitalizations. We pursue two types of assumptions that enable extrapolation from non-COVID hospital populations to the general population: (i) monotone selection into hospitalization and (ii) risk-independent hospitalization.
    keywords: bounds; covid; data; hospital; hospitalizations; population; prevalence; sample; sars; test; testing
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        item: #429 of 7819
          id: cord-180457-047iqerh
      author: Gorrell, Genevieve
       title: MP Twitter Abuse in the Age of COVID-19: White Paper
        date: 2020-06-10
       words: 5692
      flesch: 56
     summary: Higher abuse levels were associated with hashtags blaming China for the pandemic. [6] In previous studies, we have found Conservatives receiving higher abuse levels, yet here we see Labour politicians receiving more abuse in most periods.
    keywords: abuse; attention; covid-19; high; levels; mps; period; replies; table; tweets; twitter; virus
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        item: #430 of 7819
          id: cord-180835-sgu7ayvw
      author: Kolic, Blas
       title: Data-driven modeling of public risk perception and emotion on Twitter during the Covid-19 pandemic
        date: 2020-08-03
       words: 8288
      flesch: 47
     summary: key: cord-180835-sgu7ayvw authors: Kolic, Blas; Dyer, Joel title: Data-driven modeling of public risk perception and emotion on Twitter during the Covid-19 pandemic date: 2020-08-03 journal: nan DOI: nan sha: doc_id: 180835 cord_uid: sgu7ayvw Successful navigation of the Covid-19 pandemic is predicated on public cooperation with safety measures and appropriate perception of risk, in which emotion and attention play important roles. Signatures of public emotion and attention are present in social media data, thus natural language analysis of this text enables near-to-real-time monitoring of indicators of public risk perception.
    keywords: affect; countries; country; covid-19; data; death; law; number; pandemic; perception; public; risk; twitter; words
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        item: #431 of 7819
          id: cord-182237-brzv7z2n
      author: Rizk-Allah, Rizk M.
       title: COVID-19 forecasting based on an improved interior search algorithm and multi-layer feed forward neural network
        date: 2020-04-06
       words: 3968
      flesch: 47
     summary: no. of infected individuals by the means of forecasting model) and thus can help in developing drastic containment measures for the officials to avoid the epidemic spreading of this virus. This motivated us to presents a promising alternative model for forecasting tasks with the aim to achieve more accurate outcomes and avoid the previous limitations by integrating the strengths of a chaotic-based parallelization scheme and interior search method to attain better results.
    keywords: algorithm; covid-19; forecasting; isacl; mfnn; model; neural; optimization; search; training
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        item: #432 of 7819
          id: cord-183600-wxfq90zq
      author: Arthur, Rudy
       title: Studying the UK Job Market During the COVID-19 Crisis with Online Job Ads
        date: 2020-10-07
       words: 4379
      flesch: 60
     summary: We will use topic modelling and location inference methods on job vacancy data to cross section the data by geography and occupational sector. Analysis of vacancy postings in Sweden, which has had probably the least restrictive lockdown in Europe, shows a drop in job adverts by around 40%
    keywords: adverts; covid-19; data; job; jobs; lockdown; market; number; time
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        item: #433 of 7819
          id: cord-184424-t8yhu7p8
      author: Miralles-Pechu'an, Luis
       title: A Deep Q-learning/genetic Algorithms Based Novel Methodology For Optimizing Covid-19 Pandemic Government Actions
        date: 2020-05-15
       words: 7042
      flesch: 55
     summary: The presented problem is very similar to any Markov Decision Processes (MDP) where there are different states and there is an agent that takes different actions and gets rewards from the environment for those actions [8] . To optimize the best sequences of actions governments can take, we propose a methodology with two approaches, one based on Deep Q-Learning and another one based on Genetic Algorithms.
    keywords: actions; covid-19; dql; economy; learning; model; number; pandemic; population
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        item: #434 of 7819
          id: cord-184685-ho72q46e
      author: Huang, Tongtong
       title: Population stratification enables modeling effects of reopening policies on mortality and hospitalization rates
        date: 2020-08-10
       words: 4853
      flesch: 42
     summary: Among existing models, the ODE compartment-based models occupy a middle ground between network models at the individual-level and purely count-driven statistical analyses that are disease-dynamics-agnostic, which will be our main interest in this paper. Compartment models, which originated in the early 20th century
    keywords: contact; covid-19; data; hcd; hospitalization; model; mortality; policies; population; reopening
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        item: #435 of 7819
          id: cord-184744-oyc2djxk
      author: Parvez, Md Sorwer Alam
       title: Virtual Screening of Plant Metabolites against Main protease, RNA-dependent RNA polymerase and Spike protein of SARS-CoV-2: Therapeutics option of COVID-19
        date: 2020-05-22
       words: 3659
      flesch: 41
     summary: Drug discoveries & therapeutics Research and development on therapeutic agents and vaccines for COVID-19 and related human coronavirus diseases Quantitative structure-activity relationship and molecular docking revealed a potency of anti-hepatitis C virus drugs against human corona viruses From SARS to MERS, thrusting coronaviruses into the spotlight Homologous recombination within the spike glycoprotein of the newly identified coronavirus may boost cross-species transmission from snake to human Structure of SARS coronavirus spike receptor-binding domain complexed with receptor Substrate specificity profiling and identification of a new class of inhibitor for the major protease of the SARS coronavirus Design of wide-spectrum inhibitors targeting coronavirus main proteases Antiviral drugs specific for coronaviruses in preclinical development. Hence, extensive in silico studies were performed to identify potential drug candidates, for example, Prulifloxacin, Bictegravir, Nelfinavir, and Tegobuvi, were identified as repurposing candidates against COVID-19 by looking for drugs with high binding capacity with SARS-CoV main protease [28] .
    keywords: cov-2; covid-19; drug; inhibitors; kcal; protease; protein; rna; sars; spike
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        item: #436 of 7819
          id: cord-185121-f6vjm4j4
      author: Paiva, Henrique Mohallem
       title: A computational tool for trend analysis and forecast of the COVID-19 pandemic
        date: 2020-10-20
       words: 7052
      flesch: 50
     summary: For instance, when analysing the values of γ : presented in Figure 10 -(a) and Figure 12 -(a), it can be seen that such values are γ : = 0.963 and γ : = 0.873 for the city and for the state of São Paulo, respectively. Analyzing γ ‹ • for different values of k enables the conclusion of whether the convergence has occurred or not within variable window sizes.
    keywords: analysis; covid-19; curve; data; figure; model; number; parameters; trend; value
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        item: #437 of 7819
          id: cord-185125-be11h9wn
      author: Baldea, Ioan
       title: What Can We Learn from the Time Evolution of COVID-19 Epidemic in Slovenia?
        date: 2020-05-25
       words: 2405
      flesch: 41
     summary: To briefly remind, standard logistical growth in time t of an infected population n = n(t) follows an ordinary differential equation containing two constants (input model parameters): the (intrinsic) infection rate κ(> 0) and the so called carrying capacity N. Estimating model parameters from data fitting in a certain time interval to make predictions can easily run into a difficulty like that described in the first paragraph of Section 2.3.
    keywords: covid-19; equation; model; time
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        item: #438 of 7819
          id: cord-186831-724br56j
      author: Chen, Xiaocong
       title: Momentum Contrastive Learning for Few-Shot COVID-19 Diagnosis from Chest CT Images
        date: 2020-06-16
       words: 4250
      flesch: 55
     summary: Besides the diagnosis, lots of works are using the segmentation technique to conduct the detection (Chen et al., 2020a; Shi et al., 2020b; Chen et al., 2020d) . (Chen et al., 2020b) .
    keywords: covid-19; diagnosis; et al; images; learning; samples
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        item: #439 of 7819
          id: cord-187703-40382yjq
      author: Buzzell, Andrew
       title: COVID-19 Misinformation and Disinformation on Social Networks -- The Limits of Veritistic Countermeasures
        date: 2020-08-03
       words: 3797
      flesch: 19
     summary: The editorial role of platforms should not be framed solely as the management of epistemic pollution, but instead as managing the epistemic environment in which narratives and social epistemic processes take place. The editorial role of platforms should not be framed solely as the management of epistemic pollution, but instead as managing the epistemic environment in which narratives and social epistemic processes take place.
    keywords: content; covid-19; environment; fact; media; misinformation; platforms; pollution
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        item: #440 of 7819
          id: cord-189256-72eumkal
      author: Santosh, Roshan
       title: Detecting Emerging Symptoms of COVID-19 using Context-based Twitter Embeddings
        date: 2020-11-08
       words: 2871
      flesch: 48
     summary: In this study, we present an iterative learning approach to generate such a master list of COVID-19 symptoms, using the identification of words matching a specific symptom context. A high k may be chosen to yield the subset of COVID-19 symptoms that are more robustly associated with the disease, at the cost of missing infrequent (albeit potentially specific) disease markers.
    keywords: approach; context; covid-19; embedding; seed; symptoms; word
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        item: #441 of 7819
          id: cord-189307-qb0s06tl
      author: Wang, Linda
       title: COVID-Net: A Tailored Deep Convolutional Neural Network Design for Detection of COVID-19 Cases from Chest X-Ray Images
        date: 2020-03-22
       words: 4340
      flesch: 34
     summary: High architectural diversity and selective long-range connectivity can be observed as it is tailored for COVID-19 case detection from CXR images. Furthermore, it can be observed that there is considerable architectural diversity and selective long-range connectivity in the COVID-Net architecture, which reflects the fact that the machine-driven design exploration has tailored the network architecture at a very fine level of granularity for COVID-19 case detection from CXR images to achieve strong representational capacity for a specific task.
    keywords: cases; covid; covid-19; cxr; design; images; net; network
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        item: #442 of 7819
          id: cord-189629-7qaqu02f
      author: Tan, Tao
       title: Pristine annotations-based multi-modal trained artificial intelligence solution to triage chest X-ray for COVID-19
        date: 2020-11-10
       words: 4741
      flesch: 45
     summary: The contribution of our work builds on establishing a multi-modal protocol for our analysis and downstream classification of X-ray images. The inference pipleline is exclusively based on X-ray images, not requiring CT data.
    keywords: annotations; covid-19; data; disease; images; mask; ray; segmentation; synthetic
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        item: #443 of 7819
          id: cord-190407-l9mutkby
      author: Ziems, Caleb
       title: Racism is a Virus: Anti-Asian Hate and Counterhate in Social Media during the COVID-19 Crisis
        date: 2020-05-25
       words: 6244
      flesch: 59
     summary: Among the 7,841,130 users who tweet about COVID-19, most of the Figure 4 shows the distribution of the number of hate tweets (counterhate tweets, respectively) made by hate users (counterhate users, resp.). Hate tweets are more frequent than counterhate tweets.
    keywords: bots; counterhate; covid-19; dataset; hate; speech; tweets; users
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        item: #444 of 7819
          id: cord-192409-vhd7gjmf
      author: Goldstein, Elisha
       title: COVID-19 Classification of X-ray Images Using Deep Neural Networks
        date: 2020-10-03
       words: 3400
      flesch: 46
     summary: In addition, these datasets were compiled from various sources, often using one source only for COVID-19 images and another only for COVID-19 negative images. They include a limited number of positive COVID-19 CXR images, which can cause the model to overfit, as it is exposed to a relatively small number of characteristics from the data which can impair the ability to generalize to external datasets.
    keywords: covid-19; cxr; data; images; network; patients; ray
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        item: #445 of 7819
          id: cord-192653-6cv7qlcu
      author: Alam, Firoj
       title: Fighting the COVID-19 Infodemic in Social Media: A Holistic Perspective and a Call to Arms
        date: 2020-07-15
       words: 3794
      flesch: 50
     summary: We configured MicroMappers to allow labeling COVID-19 tweets in English and Arabic for all seven questions. We further plan to release annotation platforms for other languages.
    keywords: annotation; arabic; covid-19; english; infodemic; media; tweet
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        item: #446 of 7819
          id: cord-195263-i4wyhque
      author: Heider, Philipp
       title: COVID-19 mitigation strategies and overview on results from relevant studies in Europe
        date: 2020-05-11
       words: 4355
      flesch: 49
     summary: Past studies have shown that countermeasures are able to reduce reproduction numbers or transmission rates in epidemics. Past studies have shown that countermeasures are able to reduce reproduction numbers or transmission rates in epidemics.
    keywords: epidemic; growth; measures; model; number; rate; reproduction; spread
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        item: #447 of 7819
          id: cord-195929-cgabxs19
      author: Aggarwal, Jai
       title: Exploration of Gender Differences in COVID-19 Discourse on Reddit
        date: 2020-08-13
       words: 3300
      flesch: 42
     summary: We see that males tend to focus more on economic and political topics than females (rows 1 and 7); conversely, females focus far more on social topics than did males (row 2). Research on gender differences in language has a long history spanning psychology, gender studies, sociolinguistics, and, more recently, computational linguistics.
    keywords: covid; differences; gender; male; topical; topics
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        item: #448 of 7819
          id: cord-196129-3zfeamgs
      author: Demertzis, Konstantinos
       title: Flattening the COVID-19 Curve: The"Greek"case in the Global Pandemic
        date: 2020-10-09
       words: 5642
      flesch: 38
     summary: Overall, provided that they yield high determination, polynomial regression models should be used in typical cases to avoid excessive solutions leading to over-fitting. Also, it proposes a hybrid spline regression and complex network model of social distance measures evaluating and interpreting the spread of the disease.
    keywords: covid-19; curve; disease; et al; greece; infection; model; regression; splines; spread; time
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        item: #449 of 7819
          id: cord-197480-qmzkpcmn
      author: Motamed, Saman
       title: RANDGAN: Randomized Generative Adversarial Network for Detection of COVID-19 in Chest X-ray
        date: 2020-10-06
       words: 4108
      flesch: 48
     summary: To the best of our knowledge, this study is the first of its kind, using semi-supervised learning for detection of COVID-19 in medical images and reporting performance accuracy on the entire cohort of COVID-19 positive images without the need to use any of the COVID-19 positive images to train our model. One of the advantages of our semi-supervised model compared to supervised models is the ability to test our model on not only a subset, but all of COVID-19 positive images as we do not use any of the images to train our model.
    keywords: covid-19; covidx; dataset; detection; images; model; pneumonia; test
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        item: #450 of 7819
          id: cord-197818-asd39zbj
      author: Wu, Kai
       title: Magnetic Immunoassays: A Review of Virus and Pathogen Detection Before and Amidst the Coronavirus Disease-19 (COVID-19)
        date: 2020-07-09
       words: 5635
      flesch: 29
     summary: A novel magnetic bead bioassay platform using a microchip-based sensor for infectious disease diagnosis Nuclear magnetic resonance biosensor for rapid detection of Vibrio parahaemolyticus Biomed Detection of pathogen Escherichia coli O157: H7 with a wireless magnetoelastic-sensing device amplified by using chitosan-modified magnetic Fe3O4 nanoparticles Sens Rapid detection of Salmonella in milk by biofunctionalised magnetic nanoparticle cluster sensor based on nuclear magnetic resonance Multiplex measurement of twelve tumor markers using a GMR multi-biomarker immunoassay biosensor An integrated giant magnetoimpedance biosensor for detection of biomarker Development of a multiplexed giant magnetoresistive biosensor array prototype to quantify ovarian cancer biomarkers Magnetic detection of mercuric ion using giant magnetoresistance-based biosensing system Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection On the electro-dynamic qualities of metals:-Effects of magnetization on the electric conductivity of nickel and of iron Anisotropic magnetoresistance in ferromagnetic 3d alloys Electrical resistivity of ferromagnetic nickel and iron based alloys Friederich A and Chazelas J 11 Giant Magnetoresistance of (001)Fe/(001)Cr Magnetic Superlattices Enhanced magnetoresistance in layered magnetic structures with antiferromagnetic interlayer exchange Magnetically engineered spintronic sensors and memory Proc Electron microscopy of giant magnetoresistive granular Au Co alloys Microstructural influence on magnetic properties and giant magnetoresistance of melt-spun gold-cobalt Scr Giant magnetoresistance in electrodeposited Co-Ag granular films Magnetic properties and giant magnetoresistance in electrodeposited Co-Ag granular Elastic magnetic sensor with isotropic sensitivity for in-flow detection of magnetic objects Rsc Adv Direct transfer of magnetic sensor devices to elastomeric supports for stretchable electronics A theoretical study of an amorphous aluminium oxide layer used as a tunnel barrier in a magnetic tunnel junction Properties of native ultrathin aluminium oxide tunnel barriers Giant tunnelling magnetoresistance at room temperature with MgO (100) tunnel barriers High tunnel magnetoresistance at room temperature in fully epitaxial Fe/MgO/Fe tunnel junctions due to coherent spin-polarized tunneling Large area and low aspect ratio linear magnetic tunnel junctions with a soft-pinned sensing layer Tunable linear magnetoresistance in MgO magnetic tunnel junction sensors using two pinned CoFeB electrodes Wheatstone bridge sensor composed of linear MgO magnetic tunnel junctions Electrical noise in hysteretic ferromagnet-insulatorferromagnet tunnel junctions Magnetic nanoparticles in nanomedicine: a review of recent advances Biocompatibility of a Magnetic Tunnel Junction sensor array for the detection of neuronal signals in culture Advances in Magnetoresistive Biosensors Micromachines Giant Magnetoresistance-based Biosensor for Detection of Influenza A Virus Front Portable GMR Handheld Platform for the Detection of Influenza A Virus ACS Sens Portable, one-step, and rapid GMR biosensor platform with smartphone interface Quick genotyping detection of HBV by giant magnetoresistive biochip combined with PCR and line probe assay A novel HBV genotypes detecting system combined with microfluidic chip, loop-mediated isothermal amplification and GMR sensors Separable detecting of Escherichia coli O157H: H7 by a giant magneto-resistance-based bio-sensing system Sens DARPin based GMR Biosensor for the detection of ESAT-6 Tuberculosis Protein Tuberculosis Biofunctionalization of monodisperse magnetic nanoparticles and their use as biomolecular labels in a magnetic tunnel junction based sensor Quantitative detection of DNA labeled with magnetic nanoparticles using arrays of MgO-based magnetic tunnel junction sensors Detection of DNA labeled with magnetic nanoparticles using MgO-based magnetic tunnel junction sensors A 12-channel dual-lock-in platform for magneto-resistive DNA detection with ppm resolution Integrated platform for detecting pathogenic DNA via magnetic tunneling junctionbased biosensors Sens Detection of HIV-1 antigen based on magnetic tunnel junction sensor and magnetic nanoparticles Chin Multiplex biosensing based on highly sensitive magnetic nanolabel quantification: rapid detection of botulinum neurotoxins A, B, and E in liquids Magnetic Particle Spectroscopy for Detection of Influenza A Virus Subtype H1N1 Brief Communication: Magnetic Immuno-Detection of SARS-CoV-2 specific Antibodies bioRxiv Portable nuclear magnetic resonance biosensor and assay for a highly sensitive and rapid detection of foodborne bacteria in complex matrices Magnetic barcode assay for genetic detection of pathogens New type of biosensor based on magnetic nanoparticle detection Magnetic particle detection by frequency mixing for immunoassay applications Tomographic imaging using the nonlinear response of magnetic particles Magnetic particle spectroscopy-based bioassays: methods, applications, advances, and future opportunities Molecular sensing with magnetic nanoparticles using magnetic spectroscopy of nanoparticle Brownian motion Evaluating blood clot progression using magnetic particle spectroscopy Nanomagnetic lateral flow assay for high-precision quantification of diagnostically relevant concentrations of serum TSH Talanta 120961 Ultrasensitive quantitative detection of small molecules with rapid lateral-flow assay based on high-affinity bifunctional ligand and magnetic nanolabels Anal Magnetic Nanoparticle Relaxation Dynamics-Based Magnetic Particle Spectroscopy for Rapid and Wash-Free Molecular Sensing Quantification of magnetic nanoparticles by compensating for multiple environment changes simultaneously Analytical platform with selectable assay parameters based on three functions of magnetic nanoparticles: demonstration of highly sensitive rapid quantitation of staphylococcal enterotoxin B in food Rapid lateral flow assays based on the quantification of magnetic nanoparticle labels for multiplexed immunodetection of small molecules: application to the determination of drugs of abuse Microchim Magnetic dynamics of ferrofluids: mathematical models and experimental investigations Investigating the effect of magnetic dipole-dipole interaction on magnetic particle spectroscopy: implications for magnetic nanoparticle-based bioassays and magnetic particle imaging Temperature-dependent MPS measurements Temperature of the magnetic nanoparticle microenvironment: estimation from relaxation times Superparamagnetic nanoparticle-based viscosity test Relaxation-based viscosity mapping for magnetic particle imaging High-moment magnetic nanoparticles Silver and gold nanoparticles as multi-chromatic lateral flow assay probes for the detection of food allergens A smartphone readout system for gold nanoparticle-based lateral flow assays: application to monitoring of digoxigenin Microchim Magnetic quantum dot based lateral flow assay biosensor for multiplex and sensitive detection of protein toxins in food samples Quantum dot-based lateral flow test strips for highly sensitive detection of the tetanus antibody A highly sensitive dual-color lateral flow immunoassay for brucellosis using one-step synthesized latex microspheres Miniature magnetic resonance system for point-of-care diagnostics Saturation-transfer difference (STD) NMR: a simple and fast method for ligand screening and characterization of protein binding Hepatitis B virus X protein (HBx)-induced abnormalities of nucleic acid metabolism revealed by 1 H-NMR-based metabonomics NMR characterization of the interaction between Bcl-xL and the BH3-like motif of hepatitis B virus X protein Computer aided design and NMR characterization of an oligopeptide targeting the Ebola virus VP24 protein NMR interaction studies of Neu5Ac-α-(2, 6)-Gal-β-(1-4)-GlcNAc with influenza-virus hemagglutinin expressed in transfected human cells Rapid and specific influenza virus detection by functionalized magnetic nanoparticles and mass spectrometry Ferromagnetic resonance biosensor for homogeneous and volumetric detection of DNA ACS Sens A promising magnetic SERS immunosensor for sensitive detection of avian influenza virus Dendronized magnetic nanoparticles for HIV-1 capture and rapid diagnostic Multiplex immunoassays of equine virus based on fluorescent encoded magnetic composite nanoparticles Anal A magnetic molecularly imprinted optical chemical sensor for specific recognition of trace quantities of virus RSC Adv Fast and sensitive detection of Japanese encephalitis virus based on a magnetic molecular imprinted polymer-resonance light scattering sensor Simultaneous detection of multiple viruses based on chemiluminescence and magnetic separation COVID-19): role of chest CT in diagnosis and management Am Profiling early humoral response to diagnose novel coronavirus disease (COVID-19) Improved molecular diagnosis of COVID-19 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse transcription-PCR assay validated in vitro and with clinical specimens The epidemiology, diagnosis and treatment of COVID-19 Diagnosis of the Coronavirus disease (COVID-19): rRT-PCR or CT? Magnetic sinusoidal magnetic field with frequency f is applied and higher odd harmonics at 3f (the 3 rd harmonic), 5f (the 5 th harmonic), 7f (the 7 th harmonic), … are observed due to the nonlinear magnetic responses of MNPs.
    keywords: coronavirus; cov-2; covid-19; detection; gmr; immunoassay; magnetoresistance; mnps; nmr; novel; platforms; sars; sensitivity; sensors; tunnel; virus
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        item: #451 of 7819
          id: cord-197922-i1ojh8jj
      author: Kapoor, Amol
       title: Examining COVID-19 Forecasting using Spatio-Temporal Graph Neural Networks
        date: 2020-07-06
       words: 3792
      flesch: 50
     summary: We run several experiments showing the power of novel mobility data within the GNN framework, and conclude with an analysis of mobility data and its potential in tracking disease spread. However, researchers have correctly noticed that the widespread use of GPS enabled mobile devices provides a novel and highly accurate source of mobility data, and have called upon the epidemiological community to make ample use of this powerful new data source
    keywords: covid-19; data; graph; layer; location; mobility; model; neural; time
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        item: #452 of 7819
          id: cord-198180-pwmr3m4o
      author: Gupta, Deepti
       title: Future Smart Connected Communities to Fight COVID-19 Outbreak
        date: 2020-07-20
       words: 8235
      flesch: 43
     summary: Smart devices have the potential to be a major breakthrough in efforts to control and fight against the current pandemic situation. It is responsible for connecting physical sensors, smart devices, edge compute nodes or cloudlets, and cloud services with different technologies, and is also used for transmitting and processing sensor data.
    keywords: applications; challenges; cloud; control; covid-19; data; devices; health; home; hospital; internet; iot; people; privacy; sensors; smart; store; things
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        item: #453 of 7819
          id: cord-198272-s0lk1812
      author: Bairagi, Anupam Kumar
       title: Controlling the Outbreak of COVID-19: A Noncooperative Game Perspective
        date: 2020-07-27
       words: 5582
      flesch: 51
     summary: The total incentive (averaging of 50 runs) for varying percentage of home isolation individuals with different sample size are shown in Figure 4 . From this figure, we observe that the total payoff increases with increasing number of home isolation individuals for all considered cases.
    keywords: cases; covid-19; distancing; game; home; individuals; isolation; lockdown; model; strategy
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        item: #454 of 7819
          id: cord-199156-7yxzj7tw
      author: Chan, Ho Fai
       title: Risk Attitudes and Human Mobility during the COVID-19 Pandemic
        date: 2020-06-10
       words: 6231
      flesch: 44
     summary: This fits nicely into the suggestion that a person who has not made peace with his losses is likely to accept gambles that would be unacceptable to him otherwise (29, p. 287), which is consistent with risk preference changes in a disaster situation (10). We find that, with respect to risk preferences, the changes to visitation patterns (compared to their respective baseline) are relatively greater for areas with lower average willingness to take risk, following the pandemic declaration.
    keywords: behavior; change; covid-19; declaration; level; measures; mobility; pandemic; regions; risk; taking
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        item: #455 of 7819
          id: cord-199863-5j01k5v6
      author: Verenich, Edward
       title: Improving Explainability of Image Classification in Scenarios with Class Overlap: Application to COVID-19 and Pneumonia
        date: 2020-08-06
       words: 3393
      flesch: 43
     summary: This paper presents a new technique to distinguish between COVID-19 and regular pneumonia in X-ray imagery in a more explainable fashion by using class activation maps. Each input image (I) is fed to both expert networks to obtain class activation maps (CAM 1 , CAM 2 ) which are then used by our directed kernel function K to localize regions in I where the expert network for the class of interest (N 1 ) is more confident.
    keywords: activation; class; covid-19; expert; image
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        item: #456 of 7819
          id: cord-201798-doi5w7tb
      author: Seto, Christopher
       title: Commuting Network Spillovers and COVID-19 Deaths Across US Counties
        date: 2020-10-02
       words: 3513
      flesch: 42
     summary: Economic disadvantage, concentration of racial/ethnic minority groups, and urban population are associated with higher rates of COVID-19 cases and deaths, while a higher concentration of non-Hispanic White population is associated with lower COVID-19 cases and deaths (Tai et al., 2020) . We utilized 3-level mixed effects negative binomial regression models to estimate the impact of network COVID-19 exposure on county confirmed cases and deaths over time.
    keywords: cases; causal; commuting; counties; county; covid-19; deaths; network; time
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        item: #457 of 7819
          id: cord-202465-38oeau38
      author: Voorhees, Ellen
       title: TREC-COVID: Constructing a Pandemic Information Retrieval Test Collection
        date: 2020-05-09
       words: 4371
      flesch: 55
     summary: Figure 4 shows a box-and-whiskers plot of the number of judged documents in the top 50 ranks per topic for all submitted runs. Figure 4 shows statistics computed over judged documents, not relevant documents only.
    keywords: collection; covid; documents; judgments; round; runs; topic; trec
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        item: #458 of 7819
          id: cord-202824-jb47s9qt
      author: Zhang, Pengyi
       title: DRR4Covid: Learning Automated COVID-19 Infection Segmentation from Digitally Reconstructed Radiographs
        date: 2020-08-26
       words: 5907
      flesch: 44
     summary: Such controllability of the strength of radiological signs of COVID-19 infection in DRRs is very helpful to make full use of the available CT volumes and to determine the precise infection masks to train infection segmentation models. Given CT scans with voxel-level infection annotations and unlabeled CXRs, we aim to learn deep models to perform automated COVID-19 infection segmentation on CXRs.
    keywords: adaptation; classification; covid-19; covid-19 infection; cxrs; domain; drrs; infection; segmentation
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        item: #459 of 7819
          id: cord-203191-7ftg6bfx
      author: Guo, Kai
       title: Identification of Repurposal Drugs and Adverse Drug Reactions for Various Courses of Coronavirus Disease 2019 (COVID-19) Based on Single-cell RNA Sequencing Data
        date: 2020-05-16
       words: 3736
      flesch: 39
     summary: The drug connectivity score (CS) with a negative value smaller than -90 was used to determine candidate drugs and compounds. Connecting to the LINCS database of small-molecule perturbations on gene expression, we identified candidate drugs and compounds that can reverse these upregulated and downregulated genes via the CLUE platform.
    keywords: cell; coronavirus; covid-19; data; disease; drugs; inhibitor; patients; potential; sars
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        item: #460 of 7819
          id: cord-204060-ddve4mga
      author: Li, Tianyang
       title: Robust Screening of COVID-19 from Chest X-ray via Discriminative Cost-Sensitive Learning
        date: 2020-04-27
       words: 6553
      flesch: 49
     summary: The first class is healthy X-ray images, the second class is confirmed COVID-19 X-ray images, and the third class is other confirmed pneumonia X-ray images, which include both bacterial and viral pneumonia. Classification of covid-19 in chest x-ray images using detrac deep convolutional neural network Covid-caps: A capsule networkbased framework for identification of covid-19 cases from x-ray images Covid-19: automatic detection from x-ray images utilizing transfer learning with convolutional neural networks Support vector machines with example dependent costs Classification and regression trees Deep learning-based model for detecting 2019 novel coronavirus pneumonia on high-resolution computed tomography: a prospective study Imagenet: A large-scale hierarchical image database Leveraging the wisdom of the crowd for fine-grained recognition Metacost: A general method for making classifiers cost-sensitive Maximum-entropy fine grained classification Covid-resnet: A deep learning framework for screening of covid19 from radiographs Radiation dose in computed tomography Pv-lvnet: Direct left ventricle multitype indices estimation from 2d echocardiograms of paired apical views with deep neural networks Estimating uncertainty and interpretability in deep learning for coronavirus (covid-19) detection
    keywords: center; chest; class; classification; cost; covid-19; learning; loss; score; screening
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        item: #461 of 7819
          id: cord-204125-fvd6d44c
      author: Chowdhury, Muhammad E. H.
       title: An early warning tool for predicting mortality risk of COVID-19 patients using machine learning
        date: 2020-07-29
       words: 3887
      flesch: 44
     summary: The prognostic model, nomogram and LNLCA score can help in early detection of high mortality risk of COVID-19 patients, which will help doctors to improve the management of patient stratification. key: cord-204125-fvd6d44c authors: Chowdhury, Muhammad E. H.; Rahman, Tawsifur; Khandakar, Amith; Al-Madeed, Somaya; Zughaier, Susu M.; Doi, Suhail A. R.; Hassen, Hanadi; Islam, Mohammad T. title: An early warning tool for predicting mortality risk of COVID-19 patients using machine learning date: 2020-07-29 journal: nan DOI: nan sha: doc_id: 204125 cord_uid: fvd6d44c COVID-19 pandemic has created an extreme pressure on the global healthcare services.
    keywords: coronavirus; covid-19; death; disease; group; mortality; patients; risk; score
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        item: #462 of 7819
          id: cord-205189-4be24yda
      author: Asawa, Parth
       title: COVID-19 in Spain and India: Comparing Policy Implications by Analyzing Epidemiological and Social Media Data
        date: 2020-10-26
       words: 4260
      flesch: 50
     summary: Thus, we believe that this research can be explored further with potentially more statistically significant findings through access to larger datasets In this paper, we presented a methodology to determine crowd responses to governmental policies that can impact health and new case predictions in real-time, and evaluate those responses to provide direction for new public health policy. Government policies, especially in developing nations, based on the epidemiological data, ignore the population-specific behaviors of culture, ideology, and politics that hinder these policies' implementation.
    keywords: cases; covid-19; data; india; kerala; mumbai; policies; policy; spain; twitter
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        item: #463 of 7819
          id: cord-206006-8l7hrany
      author: Wang, Rui
       title: Mutations on COVID-19 diagnostic targets
        date: 2020-05-05
       words: 1611
      flesch: 47
     summary: Unfortunately, Table 2 shows that all of the US CDC designated COVID-19 diagnostic primers have been compromised. Our findings enable researchers to target the most conservative SARS-CoV-2 genes and proteins for the design and development of COVID-19 diagnostic reagents, preventive vaccines, and therapeutic medicines.
    keywords: cov-2; covid-19; gene; primers; sars
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        item: #464 of 7819
          id: cord-207180-k6f6cmyn
      author: Shahrezaye, Morteza
       title: COVID-19's (mis)information ecosystem on Twitter: How partisanship boosts the spread of conspiracy narratives on German speaking Twitter
        date: 2020-09-27
       words: 3578
      flesch: 43
     summary: In terms of content moderation by Twitter, on average 7.3% of conspiracy narrative tweets are deleted after a certain period of time which is significantly higher than 6% of tweets in the control group. Based on this analysis, 1.31% of COVID-19 conspiracy narrative tweets are suspected to be posted by automated accounts.
    keywords: conspiracy; covid-19; narratives; tweets; twitter; users
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        item: #465 of 7819
          id: cord-207242-hb1r2aw7
      author: Ghader, Sepehr
       title: Observed mobility behavior data reveal social distancing inertia
        date: 2020-04-30
       words: 3092
      flesch: 47
     summary: The study revealed that statistics related to social distancing, namely trip rate, miles traveled per person, and percentage of population staying at home have all showed an unexpected trend, which we named social distancing inertia. Another interesting observation was the universality of social distancing inertia.
    keywords: behavior; covid-19; data; distancing; home; inertia; location
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        item: #466 of 7819
          id: cord-207839-h8mcmqnc
      author: Amran, Dor
       title: Automated triage of COVID-19 from various lung abnormalities using chest CT features
        date: 2020-10-24
       words: 2315
      flesch: 38
     summary: We next describe the features extracted: Lungs statistics features: volumetric lung features and HU analysis features. Analysis features include both the HU volume and ratio (calculated in [%]) in division to the anatomical structures, detected in three HU windows: Opacities statistics features: volumetric ([cm 3 ]) and ratio ([%]) features quantifying all detected abnormalities simultaneously in division to the anatomical structures.
    keywords: analysis; chest; classification; covid-19; features; lung
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        item: #467 of 7819
          id: cord-207989-hn37wkhf
      author: Bras, Pierre Le
       title: Visualising COVID-19 Research
        date: 2020-05-13
       words: 4142
      flesch: 45
     summary: The interface, moreover, can help predict the trends in other countries and discover exciting movements in the relevance of other various research topics of the pandemic. Lastly, Ahamed & Samad [5] use a method of topic analysis where topics are identified using betweenness centrality measurement [12] .
    keywords: analysis; covid-19; figure; pandemic; publications; research; sub; topic; trend; visualisation
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        item: #468 of 7819
          id: cord-208177-m8q6dyfx
      author: Chaisemartin, Cl'ement de
       title: BCG vaccination in infancy does not protect against COVID-19. Evidence from a natural experiment in Sweden
        date: 2020-06-08
       words: 2065
      flesch: 45
     summary: key: cord-208177-m8q6dyfx authors: Chaisemartin, Cl'ement de; Chaisemartin, Luc de title: BCG vaccination in infancy does not protect against COVID-19. We used regression discontinuity to assess the effect of BCG vaccination on Covid-19 related outcomes.
    keywords: bcg; covid-19; effect; vaccination
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        item: #469 of 7819
          id: cord-208179-9pwjnrgl
      author: Farrell, Tracie
       title: Vindication, Virtue and Vitriol: A study of online engagement and abuse toward British MPs during the COVID-19 Pandemic
        date: 2020-08-12
       words: 13386
      flesch: 51
     summary: In order to understand and contextualise the level of abuse MPs receive, we consider how ministers use social media to communicate about the crisis, and the citizen engagement that this generates. # Replies is the number of replies tweets by that demographic in the qualitative corpus received, and # Abusive is the number of those replies that were abusive (recall that the tweet is only included if it receives a high level of abuse).
    keywords: abuse; covid-19; crisis; government; hate; health; language; media; mps; online; pandemic; party; politicians; public; replies; tweets; twitter; women; work
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        item: #470 of 7819
          id: cord-208252-e0vlaoii
      author: Calvetti, Daniela
       title: Bayesian dynamical estimation of the parameters of an SE(A)IR COVID-19 spread model
        date: 2020-05-09
       words: 7818
      flesch: 43
     summary: The Epidemiology and Control of Malaria A brief history of R 0 and a recipe for its calculation On the definition and computation of the basic reproduction ratio R 0 in models for infectious diseases in heterogeneous populations The construction of next-generation matrices for compartmental epidemic models The COVID-19 data, consisting of the daily count of newly reported infection, corresponds to observations of the flux ϕ 2 : In the absence of additional populationlevel inputs, this is the data that must be used to estimate the cohort sizes and model parameters.
    keywords: asymptomatic; cohort; covid-19; data; individuals; model; number; particle; rate; transmission
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        item: #471 of 7819
          id: cord-208698-gm0b8u52
      author: Fazeli, Shayan
       title: Statistical Analytics and Regional Representation Learning for COVID-19 Pandemic Understanding
        date: 2020-08-08
       words: 6365
      flesch: 43
     summary: There have been projects such as a work at John Hopkins University that are focused on providing US county-level summaries of COVID-19 pandemic information and important attributes [12] , [13] . We provide a collection of datasets and select a large number of features to reflect on various demographics, socio-economics, mobility, and pandemic information.
    keywords: county; covid-19; data; dataset; features; information; level; pandemic; region; results; values; work
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        item: #472 of 7819
          id: cord-209619-hy27h1nd
      author: Dobin, Daniel
       title: Racial/ethnic and socioeconomic disparities of Covid-19 attacks rates in Suffolk County communities
        date: 2020-04-25
       words: 1592
      flesch: 41
     summary: key: cord-209619-hy27h1nd authors: Dobin, Daniel; School, Alexander Dobin Candlewood Middle; York, New; USA,; Laboratory, Cold Spring Harbor title: Racial/ethnic and socioeconomic disparities of Covid-19 attacks rates in Suffolk County communities date: 2020-04-25 journal: nan DOI: nan sha: doc_id: 209619 cord_uid: hy27h1nd We investigated the dependence of Covid-19 attack rates on demographic and socioeconomic factors for the communities in Suffolk County (Long Island, New York State), presently the 5th most-affected county in the United States. In this work, we investigated the dependence of Covid-19 attack rate on racial/ethnic composition and several socioeconomic metrics for the communities in Suffolk County (Long Island, New York state), presently the 5th most affected county in the United States.
    keywords: attack; covid-19; population; rate
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        item: #473 of 7819
          id: cord-213187-f1ic63o5
      author: Rahman, Akond
       title: An Exploratory Characterization of Bugs in COVID-19 Software Projects
        date: 2020-05-31
       words: 10574
      flesch: 48
     summary: An understanding of COVID-19 software categories and software bugs can give us clues on how the software engineering community can help even further in combating COVID-19. Categorization of bugs in COVID-19 software can help practitioners and researchers to (i) understand the nature of COVID-19 software bugs, (ii) construct bug detection and repair tools, and (iii) measure COVID-19 software quality by using reported frequency of bug categories as a benchmark.
    keywords: author; bug; bugs; categories; category; coding; covid-19; data; et al; example; modeling; practitioners; projects; rater; reports; software; software projects; user
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        item: #474 of 7819
          id: cord-213974-rtltf11w
      author: Lensink, Keegan
       title: Segmentation of Pulmonary Opacification in Chest CT Scans of COVID-19 Patients
        date: 2020-07-07
       words: 5520
      flesch: 47
     summary: The medical students were used to collect lung segmentation labels, while the radiologists and residents were used to collect segmentation labels for patterns of opacification. We provide open source implementations and pre-trained weights for multiple segmentation models trained on our dataset.
    keywords: covid-19; data; lung; model; opacification; patterns; scans; segmentation; set
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        item: #475 of 7819
          id: cord-215290-n1656hq0
      author: Tu, Jingxuan
       title: Exploration and Discovery of the COVID-19 Literature through Semantic Visualization
        date: 2020-07-03
       words: 4175
      flesch: 45
     summary: Each CA contains three elements: protein-A, relation type, and protein-B. We group the 24 relation types into two metatypes: RegulateActivity and Modification. We are currently working to provide graph-based visualizations of network relations that go beyond the heat map capabilities provided in Kibana-like dashboards.
    keywords: covid-19; data; entities; heat; protein; relations; tag; type; visualization
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        item: #476 of 7819
          id: cord-215345-p1iktm9v
      author: He, Bing
       title: Prediction of repurposed drugs for treating lung injury in COVID-19
        date: 2020-03-30
       words: 1282
      flesch: 38
     summary: key: cord-215345-p1iktm9v authors: He, Bing; Garmire, Lana title: Prediction of repurposed drugs for treating lung injury in COVID-19 date: 2020-03-30 journal: nan DOI: nan sha: doc_id: 215345 cord_uid: p1iktm9v Coronavirus disease (COVID-19) is an infectious disease discovered in 2019 and currently in outbreak across the world. Lung injury with severe respiratory failure is the leading cause of death in COVID-19, brought by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
    keywords: ace2; covid-19; drugs; injury; lung
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        item: #477 of 7819
          id: cord-217201-lvefk7qx
      author: Wang, Yang
       title: Ontology-based annotation and analysis of COVID-19 phenotypes
        date: 2020-08-05
       words: 2487
      flesch: 43
     summary: In this study, we systematically annotated COVID-19 clinical phenotypes and comorbidities from journal and preprint articles, and applied HP to classify these phenotypes and examine the internal patterns. In terms of COVID-19 phenotype classification, CIDO has imported the HP representations of COVID-19-related phenotypes ( Figure 1 ) and comorbidities ( Figure 4 ).
    keywords: comorbidities; covid-19; disease; loss; patients; phenotypes
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        item: #478 of 7819
          id: cord-218324-gqiapgiv
      author: Dlotko, Pawel
       title: Visualising the Evolution of English Covid-19 Cases with Topological Data Analysis Ball Mapper
        date: 2020-04-07
       words: 3587
      flesch: 56
     summary: Covid-19 case data is updated daily and may be neatly summarised in Table 2 . Case data is released by the UK Government via www.gov.uk at the local authority level.
    keywords: ball; cases; covid-19; data; space; spread
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        item: #479 of 7819
          id: cord-219107-klpmipaj
      author: Zachreson, Cameron
       title: Risk mapping for COVID-19 outbreaks using mobility data
        date: 2020-08-14
       words: 5908
      flesch: 37
     summary: Our general method is to use an Origin-Destination (OD) matrix based on Facebook mobility data to estimate the diffusion of transmission risk based on one or more identified outbreak sources. Our results indicate that mobility data can be a good predictor of geographic patterns of exposure risk from transmission centres, particularly in scenarios involving workplaces or other environments associated with habitual travel patterns.
    keywords: case; covid-19; data; facebook; mobility; mobility data; number; outbreak; risk; time; transmission
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        item: #480 of 7819
          id: cord-219520-by3gxrd8
      author: Pang, Junjie
       title: Collaborative City Digital Twin For Covid-19 Pandemic: A Federated Learning Solution
        date: 2020-11-05
       words: 4979
      flesch: 38
     summary: In particular, an FL central server manages the local updates of multiple collaborators (city DT), provides a global model which is trained in multiple iterations at different city DT systems, until the model gains the correlations between various response plan and infection trend. Such a concept leads to the advancements in both urban computing paradigm and IoT applications direct extending to smart city area recently, which termed as 'city digital twin'.
    keywords: city; covid-19; data; learning; model; response; time; training; twin
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        item: #481 of 7819
          id: cord-219681-83p1ujl4
      author: Gathergood, John
       title: The English Patient: Evaluating Local Lockdowns Using Real-Time COVID-19&Consumption Data
        date: 2020-10-08
       words: 5701
      flesch: 47
     summary: We find UK 'local lockdowns' of cities and small regions, focused on limiting how many people a household can interact with and in what settings, are effective in turning the tide on rising positive COVID-19 cases. We show that UK local lockdowns to contain virus outbreaks -covering one in four people by September 2020 -3 typically turn the tide on rising COVID-19 cases.
    keywords: areas; average; cases; consumption; covid-19; data; day; et al; local; lockdown; spending
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        item: #482 of 7819
          id: cord-219880-3wob432t
      author: Ma, Liantao
       title: CovidCare: Transferring Knowledge from Existing EMR to Emerging Epidemic for Interpretable Prognosis
        date: 2020-07-17
       words: 5688
      flesch: 44
     summary: Each medical feature contains T timesteps, as shown in Figure 2 a result, such a clinical sequence can be formulated as a âĂIJlongitudinal patient matrixâĂİ record, where one dimension represents medical features and the other denotes admission timestamps In the self-attention layer, we employ the multi-head self-attention mechanism to obtain information from the health context and better understand the correlations between medical features.
    keywords: covid-19; covidcare; dataset; features; health; learning; model; patients; prediction; source
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        item: #483 of 7819
          id: cord-222664-4qyrtzhu
      author: Coban, Mathew
       title: Attacking COVID-19 Progression using Multi-Drug Therapy for Synergetic Target Engagement
        date: 2020-07-06
       words: 11330
      flesch: 36
     summary: It was identified in Wuhan city, in the Hubei province of China in December 2019 (Chen et al., 2020; Huang et al., 2020; Zhu et al., 2020) . The spike glycoprotein is a key surface protein that interacts with cell surface receptor, angiotensinconverting enzyme 2 (Ace2) mediating entrance of the virus into host cells (Zhu et al., 2018) .
    keywords: ace2; binding; caulfield; caulfield et; compounds; cov-2; covid-19; data; docking; drug; dynamics; et al; fig; inhibitors; interaction; ligand; model; patients; protein; residues; results; sars; screening; set; simulations; site; structure; target; tmprss2; virus
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        item: #484 of 7819
          id: cord-223560-ppu6idl2
      author: Russo, Daniel
       title: Predictors of Well-being and Productivity among Software Professionals during the COVID-19 Pandemic -- A Longitudinal Study
        date: 2020-07-24
       words: 14096
      flesch: 51
     summary: Routines and agreements with family members about working times also help to be more focused. Extraversion correlated negatively with support for social distancing measures [16] , which is a proxy of stimulation (e.g., being closer to other people, will more likely result in sensory stimulation).
    keywords: covid-19; home; items; participants; people; productivity; research; scale; software; stress; study; time; variables; work; working
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        item: #485 of 7819
          id: cord-224428-t8s52emf
      author: Tandon, Hiteshi
       title: Coronavirus (COVID-19): ARIMA based time-series analysis to forecast near future
        date: 2020-04-16
       words: 2105
      flesch: 57
     summary: Figure 5 shows a comparative study of confirmed COVID-19 infection cases of India with respect to those of highly infected countries. In order to support the prevention of the disease and aid in the healthcare service preparation, we have conducted this study to examine the finest model for the prediction of confirmed COVID-19 infection cases and to employ that model for forecasting future COVID-19 infection cases in India.
    keywords: cases; covid-19; india; model
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        item: #486 of 7819
          id: cord-225145-m5udub60
      author: Kai, De
       title: Universal Masking is Urgent in the COVID-19 Pandemic: SEIR and Agent Based Models, Empirical Validation, Policy Recommendations
        date: 2020-04-22
       words: 8153
      flesch: 44
     summary: We present two models for the COVID-19 pandemic predicting the impact of universal face mask wearing upon the spread of the SARS-CoV-2 virus--one employing a stochastic dynamic network based compartmental SEIR (susceptible-exposed-infectious-recovered) approach, and the other employing individual ABM (agent-based modelling) Monte Carlo simulation--indicating (1) significant impact under (near) universal masking when at least 80% of a population is wearing masks, versus minimal impact when only 50% or less of the population is wearing masks, and (2) significant impact when universal masking is adopted early, by Day 50 of a regional outbreak, versus minimal impact when universal masking is adopted late. Face masks work in two ways: They can protect an infected person from spreading the virus (transmission), and they can limit how much the non-infected individual is exposed to the virus (absorption).
    keywords: countries; covid-19; growth; lockdown; masking; masks; model; population; public; rates; results; seir; universal; wearing
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        item: #487 of 7819
          id: cord-225347-lnzz2chk
      author: Chakraborty, Tanujit
       title: Nowcasting of COVID-19 confirmed cases: Foundations, trends, and challenges
        date: 2020-10-10
       words: 10219
      flesch: 49
     summary: As an extension of autoregressive model, Self-exciting threshold autoregressive (SE-TAR) model is used to model time series data, in order to allow for higher degree of flexibility in model parameters through a regime switching behaviour [116] . There are many approaches to test the nonlinearity in time series models, including a nonparametric kernel test and a Neural Network test [119] .
    keywords: accuracy; arima; cases; covid-19; data; datasets; ensemble; forecasting; forecasting models; forecasts; function; hybrid; models; series; series data; test; time; time series
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        item: #488 of 7819
          id: cord-225887-kr9uljop
      author: Thelwall, Mike
       title: Covid-19 Tweeting in English: Gender Differences
        date: 2020-03-24
       words: 3007
      flesch: 51
     summary: Comparing (a) with (b) gives an indication of likely gender differences overall. It focuses on one relevant aspect of public reaction: gender differences.
    keywords: covid-19; differences; gender; males; public; tweets; word
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        item: #489 of 7819
          id: cord-226263-ns628u21
      author: Ye, Yanfang
       title: $alpha$-Satellite: An AI-driven System and Benchmark Datasets for Hierarchical Community-level Risk Assessment to Help Combat COVID-19
        date: 2020-03-27
       words: 5696
      flesch: 43
     summary: In our developed system (named α-Satellite), we first develop a set of tools to collect and preprocess the large-scale and real-time pandemic related data from multiple sources, including disease related data from official public health organizations, demographic data, mobility data, and user generated data from social media; and then we devise advanced AI-driven techniques to provide hierarchical community-level risk assessment to enable actionable strategies for community mitigation. We have developed a set of crawling and preprocessing tools to collect and parse the largescale and real-time pandemic related data from multiple sources, including disease related data from official public health organizations and digital media, demographic data, mobility data, and user generated data from social media (i.e., Reddit).
    keywords: area; cases; community; county; covid-19; data; information; risk; system; time
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        item: #490 of 7819
          id: cord-226621-x7slh9n9
      author: Inuwa-Dutse, Isa
       title: A curated collection of COVID-19 online datasets
        date: 2020-07-19
       words: 3648
      flesch: 48
     summary: We manually identify users who openly dismisses Covid-19 related information put forward by credible sources such as the WHO. The work of [5] provides a large collection of Covid-19 datasets in Arabic and details about Covid-19 related articles across Wikipedia projects are being documented online 7 .
    keywords: collection; content; covid-19; data; datasets; pandemic; tweets
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        item: #491 of 7819
          id: cord-228736-x1w5pi67
      author: Suryanarayanan, Parthasarathy
       title: WNTRAC: Artificial Intelligence Assisted Tracking of Non-pharmaceutical Interventions Implemented Worldwide for COVID-19
        date: 2020-09-02
       words: 4636
      flesch: 51
     summary: The system, shown in the Figure 3 , is designed to be scalable for continuous gathering, extraction and validation of NPI events. It consists of two subsystems: a data processing pipeline for capturing and extracting potential NPI events from Wikipedia articles and a tool, WNTRAC Curator for human validation of NPI events automatically extracted using the aforementioned pipeline.
    keywords: covid-19; dataset; event; npi; npis; region; sentence; type; wikipedia; wntrac
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        item: #492 of 7819
          id: cord-229612-7xnredj7
      author: Pal, Ankit
       title: Pay Attention to the cough: Early Diagnosis of COVID-19 using Interpretable Symptoms Embeddings with Cough Sound Signal Processing
        date: 2020-10-06
       words: 3622
      flesch: 48
     summary: To overcome the limitation of the existing methods, A novel interpretable COVID-19 diagnosis AI framework is proposed in this study, which uses symptoms and cough features to classify the COVID-19 cases from non-COVID-19 cases accurately. Before extracting cough features and feeding it to Deep Neural Networks(DNN), some preprocessing of raw audio data is needed.
    keywords: cough; covid-19; data; features; model; signal; sounds; symptoms
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        item: #493 of 7819
          id: cord-229942-vofuo2g1
      author: Omae, Yuto
       title: Effectiveness of the COVID-19 Contact-Confirming Application (COCOA) based on a Multi Agent Simulation
        date: 2020-08-30
       words: 6823
      flesch: 62
     summary: Now, the amount of the difference of the total number (1) (2) (4) is calculated, where N IP (t; p p p app ) denotes the total number of infectors in t days of scenario using the app parameter p p p app , and ∆N IP (t; p p p app ) denotes the differential value. Thus, if each element of the app parameters p p p app is increased, then we believe that the number of infectors could be decreased.
    keywords: app; covid-19; infectors; number; p app; p p; rate; state
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        item: #494 of 7819
          id: cord-231762-ymz7z76i
      author: Misra, Sampa
       title: Multi-Channel Transfer Learning of Chest X-ray Images for Screening of COVID-19
        date: 2020-05-12
       words: 3703
      flesch: 50
     summary: The second (62 images) and third datasets (204 images) are COVID-19 X-ray images from Kaggle [19] , and GitHub However, there were many duplicate images in these sources, and thus after removing the duplicate images the final number of the normal, pneumonia and COVID-19 X-ray images became 1579, 4245, and 184, respectively.
    keywords: covid-19; ensemble; images; learning; models; pneumonia
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        item: #495 of 7819
          id: cord-232446-vvb2ffhv
      author: Mongia, Aanchal
       title: A computational approach to aid clinicians in selecting anti-viral drugs for COVID-19 trials
        date: 2020-07-03
       words: 7129
      flesch: 43
     summary: The drug-virus associations and the similarity information are assembled as three matrices: drug-virus association matrix (Y ), drug similarity matrix (S d ) and virus similarity matrix (S v ). We also demonstrate how the selected drugs change as the SARS-Cov-2 mutates over time, suggesting the importance of such a tool in drug prediction.
    keywords: association; completion; covid-19; database; drugs; graph; information; matrix; matrix completion; methods; prediction; similarity; techniques; virus; viruses
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        item: #496 of 7819
          id: cord-232657-deu921ma
      author: Prabhu, Shreekanth M.
       title: Surveillance of COVID-19 Pandemic using Hidden Markov Model
        date: 2020-08-14
       words: 5312
      flesch: 54
     summary: Thus, there is a very real possibility that a sizable number of COVID-19 cases are not detected on testing. There are many studies that predicted the growth of COVID-19 cases in India.
    keywords: cases; covid-19; data; disease; epidemic; india; model; pandemic; spread; states; use
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        item: #497 of 7819
          id: cord-233012-ltbvpv8b
      author: Garcia-Gasulla, Dario
       title: Global Data Science Project for COVID-19 Summary Report
        date: 2020-06-10
       words: 4754
      flesch: 57
     summary: The x-axis of Figure 19 and As for sharing bike data, we track the number of people using bikes at each bike station every 30 seconds from NYC Open Data OpenData (2020a). To investigate the effects of these travel restrictions on worldwide flights, we analyzed the decline of flights for continents and countries from public flight data.
    keywords: city; countries; covid-19; data; lockdown; march; mobility; number; people; posts; tweets
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        item: #498 of 7819
          id: cord-234254-svjajpp4
      author: Kohler, J.
       title: Robust and optimal predictive control of the COVID-19 outbreak
        date: 2020-05-07
       words: 13166
      flesch: 52
     summary: [12] in order to design control policies which minimize the number of fatalities within a time horizon of two years, without using excessive social distancing measures. Applying an optimizer to the mathematical model describing the outbreak, one can significantly reduce the number of fatalities without increasing the costs associated to decreasing the infection rate (social distancing policies, closing schools, etc.), compare Section 3.2.
    keywords: control; covid-19; fatalities; measures; model; number; outbreak; policy; rate; section; time
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        item: #499 of 7819
          id: cord-234918-puunbcio
      author: Shalu, Hrithwik
       title: A Data-Efficient Deep Learning Based Smartphone Application For Detection Of Pulmonary Diseases Using Chest X-rays
        date: 2020-08-19
       words: 4877
      flesch: 43
     summary: Using a convolutional architecture, we can achieve reliable results that exceed those of other deep learning models with near state-of-the-art performance on one-shot classification tasks. The authors chose AlexNet, GoogLeNet, Squeeznet, and Resnet18 are selected as deep transfer learning models.
    keywords: chest; covid-19; data; deep; images; learning; model; network; neural
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        item: #500 of 7819
          id: cord-234996-hah19vmk
      author: Kabiri, Aliakbar
       title: How different age groups responded to the COVID-19 pandemic in terms of mobility behaviors: a case study of the United States
        date: 2020-07-20
       words: 3656
      flesch: 42
     summary: In this paper, we attempt to fill the current gap in the literature by examining how different communities with different age groups performed social distancing by following orders such as the national emergency declaration on March 13, as well as how fast they started changing their behavior after the regulations were imposed. For this purpose, we calculated the behavior changes of people in different mobility metrics, such as percentage of people staying home during the study period (March, April, and May 2020), in different age groups in comparison to the days before the pandemic (January and February 2020), by utilizing anonymized and privacy-protected mobile device data.
    keywords: behavior; communities; distancing; groups; mobility; pandemic; people
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        item: #501 of 7819
          id: cord-235691-en6fgilb
      author: Althouse, Benjamin M.
       title: Stochasticity and heterogeneity in the transmission dynamics of SARS-CoV-2
        date: 2020-05-27
       words: 4813
      flesch: 39
     summary: Summary of COVID-19 outbreaks at licensed long-term care facilities in King County COVID-19 pandemic on cruise ships Crowding and the epidemic intensity of COVID-19 transmission Closed environments facilitate secondary transmission of coronavirus disease What settings have been linked to SARS-CoV-2 transmission clusters? In Japan, looking at clusters of transmission, researchers found closed environments facilitate secondary transmission of SARS-CoV-2 and promote SSEs; the odds ratio of SSEs in closed environments was as high as 32.6 compared with those in open spaces 43 .
    keywords: cases; cov-2; covid-19; individuals; infections; outbreak; probability; sars; sses; transmission
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        item: #502 of 7819
          id: cord-235946-6vu34vce
      author: Beskow, David M.
       title: Social Cybersecurity Chapter 13: Casestudy with COVID-19 Pandemic
        date: 2020-08-23
       words: 8974
      flesch: 58
     summary: We see a modest number of state sponsored tweets, with substantially more amplification of state sponsored accounts. It is often important to evaluate the quantity and nature of suspended accounts in any event oriented stream.
    keywords: accounts; analysis; bot; chinese; covid-19; data; figure; information; media; memes; network; operations; state; stream; twitter; use
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        item: #503 of 7819
          id: cord-236775-tshyi559
      author: Zine, Houssine
       title: Modeling the spread of COVID-19 pandemic in Morocco
        date: 2020-10-08
       words: 3405
      flesch: 44
     summary: The main objective of this section is to examine the sensitivity of the basic reproduction number R 0 with respect to model parameters by the so-called sensitivity index. The species Severe acute respiratory syndromerelated coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 The official portal of Corona virus in Morocco Estimation of the transmission risk of the 2019-nCoV and its implication for public health interventions Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Prediction of the Epidemic Peak of Coronavirus Disease in Japan Analysis and forecast of COVID-19 spreading in China Mathematical modeling of COVID-19 transmission dynamics with a case study of Wuhan Modeling the dynamics of novel coronavirus (2019-nCov) with fractional derivative Evidence on vulnerability and susceptibility to health risks associated with short-term exposure to particulate matter: A systematic review and meta-analysis The vulnerable and the susceptible Introduction to functional-differential equations On the definition and the computation of the basic reproduction ratio 0 in models for infectious diseases in heterogeneous populations Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship WHO, Coronavirus disease 2019 (COVID-19)
    keywords: covid-19; disease; measures; model; morocco
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        item: #504 of 7819
          id: cord-237140-ybfifsid
      author: Wang, Ding
       title: Impact of COVID-19 Behavioral Inertia on Reopening Strategies for New York City Transit
        date: 2020-06-23
       words: 6472
      flesch: 51
     summary: Two reopening scenarios (with and without transit capacity restrictions) are analyzed to forecast the impacts on transit mode share and road traffic. Compare the mode share in Pre-COVID model and COVID model.
    keywords: capacity; car; covid; data; matsim; model; pre; reopening; ridership; traffic; transit; trips
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        item: #505 of 7819
          id: cord-238444-v9gfh3m1
      author: Maghdid, Halgurd S.
       title: A Smartphone enabled Approach to Manage COVID-19 Lockdown and Economic Crisis
        date: 2020-04-25
       words: 3836
      flesch: 56
     summary: The more people register in the system, the better performance of the system in terms of both speed and coverage of contact tracing. However, manual contact tracing is time consuming and labor-intensive task which tremendously overload public health systems.
    keywords: area; cases; contact; covid-19; lockdown; people; system; users
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        item: #506 of 7819
          id: cord-238782-z9nb8cwt
      author: Rajinikanth, Venkatesan
       title: Firefly-Algorithm Supported Scheme to Detect COVID-19 Lesion in Lung CT Scan Images using Shannon Entropy and Markov-Random-Field
        date: 2020-04-14
       words: 3773
      flesch: 45
     summary: This dataset consists of one hundred numbers of COVID-19 images with dimension 512x512x1 pixels and all the images are associated with the GTI. In this regard, a mass screening facility for the screening of CT images as proposed in this research work will have a huge impact in terms of the reduction of this burden.
    keywords: covid-19; cti; disease; image; infection; lung; pneumonia; work
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        item: #507 of 7819
          id: cord-238881-tupom7fb
      author: Yeh, Chun-Fu
       title: A Cascaded Learning Strategy for Robust COVID-19 Pneumonia Chest X-Ray Screening
        date: 2020-04-24
       words: 3358
      flesch: 51
     summary: Suggested by medical experts, because of the efficiency and availability of CXR, we propose an AI-based screening system to recognize COVID-19 pneumonia in CXR images. The frequent changes in the available training data may require re-training the AI model to improve classification performance on COVID-19 images, while it also may degrade the overall pneumonia classification in stage 2.
    keywords: classification; covid-19; cxr; images; model; pneumonia; stage
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        item: #508 of 7819
          id: cord-239315-dk2lwsrx
      author: Magklaras, Georgios
       title: A review of information security aspects of the emerging COVID-19 contact tracing mobile phone applications
        date: 2020-05-31
       words: 6301
      flesch: 43
     summary: Before taking a closer look into the problems of contact tracing solutions, it is necessary to provide essential definitions about the concept and the technologies involved in making the transition from manual to electronic procedures. In a post-COVID-19 world, governments and technology companies turn to various aspects of mobile and general computing infrastructures to implement contact tracing solutions.
    keywords: bluetooth; contact; covid-19; data; health; information; location; privacy; proximity; smartphone; solutions; user
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        item: #509 of 7819
          id: cord-240274-igoz2ei4
      author: Subirana, Brian
       title: Hi Sigma, do I have the Coronavirus?: Call for a New Artificial Intelligence Approach to Support Health Care Professionals Dealing With The COVID-19 Pandemic
        date: 2020-04-10
       words: 2711
      flesch: 44
     summary: Feature based approaches (e.g. 17 18 19 ) can be used where is a transformation function derived from features based transfer learning approaches. key: cord-240274-igoz2ei4 authors: Subirana, Brian; Hueto, Ferran; Rajasekaran, Prithvi; Laguarta, Jordi; Puig, Susana; Malvehy, Josep; Mitja, Oriol; Trilla, Antoni; Moreno, Carlos Iv'an; Valle, Jos'e Francisco Munoz; Gonz'alez, Ana Esther Mercado; Vizmanos, Barbara; Sarma, Sanjay title: Hi Sigma, do I have the Coronavirus?: Call for a New Artificial Intelligence Approach to Support Health Care Professionals Dealing With The COVID-19 Pandemic date: 2020-04-10 journal: nan DOI: nan sha: doc_id: 240274 cord_uid: igoz2ei4 Just like your phone can detect what song is playing in crowded spaces, we show that Artificial Intelligence transfer learning algorithms trained on cough phone recordings results in diagnostic tests for COVID-19.
    keywords: approach; covid-19; data; learning; patients; transfer
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        item: #510 of 7819
          id: cord-240742-w57e1eu6
      author: Arela-Bobadilla, Ronal
       title: Excess deaths hidden 100 days after the quarantine in Peru by COVID-19
        date: 2020-07-04
       words: 3373
      flesch: 53
     summary: En primer lugar, se verificó la estacionariedad de cada una de las series de tiempo de las muertes por millón de habitantes en cada departamento. Un límite muy restrictivo como el de la muestra L1 puede mejorar el insesgamiento de la estimación; sin embargo, tiene un tamaño de muestra pequeño.
    keywords: con; covid-19; cuarentena; debido; del; días; entre; las; los; muertes; muestra; nacional; para; por; que; sin; una
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        item: #511 of 7819
          id: cord-241146-j0qperwz
      author: Lallie, Harjinder Singh
       title: Cyber Security in the Age of COVID-19: A Timeline and Analysis of Cyber-Crime and Cyber-Attacks during the Pandemic
        date: 2020-06-21
       words: 9941
      flesch: 46
     summary: A Look at Fake FIFA World Cup-themed Lotteries and Giveaways Blackmailing and passwords leaks Compromised linkedin accounts used to send phishing links via private message and inmail 10 tips to help if you are worried about coronavirus Facing down the myriad threats tied to covid-19 Threat spotlight: Coronavirus-related phishing Protecting businesses against cyber threats during covid-19 and beyond Covid aid scams and dodgy 2020 A systematic approach toward description and classification of cybercrime incidents A cyber attack modeling and impact assessment framework A taxonomy and survey of intrusion detection system design techniques, network threats and datasets Extracting narrative timelines as temporal dependency structures Classification of cyber attacks in south africa Sony's nightmare before christmas: The 2014 north korean cyber attack on sony and lessons for us government actions in cyberspace Naming the coronavirus disease (COVID-19) and the virus that causes it Cybercrime -prosecution guidance Vietnamese threat actors apt32 targeting wuhan government and chinese ministry of emergency management in latest example of covid-19 related espionage Skype phishing attack targets remote workers' passwords Fake Coronavirus Tracking Apps Are Really Malware That Stalks You How to design browser security and privacy alerts Bayesian network models in cyber security: a systematic review Google Translate Coronavirus disease (COVID-19) pandemic Latest information on Coronavirus disease 2019 (COVID-19) Research on computer network attack modeling based on attack graph Who reports fivefold increase in cyber attacks, urges vigilance search (Accessed Municipal:massive computer attack at the town hall of marseille Cyber attack on easyjet, compromised the data of nine million customers An extended model of cybercrime investigations A taxonomy of operational cyber security risks A taxonomy of technical attribution techniques for cyber attacks A taxonomy of network threats and the effect of current datasets on intrusion detection systems Chapter 1: Cyberdependent crimes Cyber-enabled crimes -fraud and theft Research Reveals Hacker Tactics: Cybercriminals Use DDoS as Smokescreen for Other Attacks on Business From cybersecurity deception to manipulation and gratification through gamification Recent ransomware attacks define the malware's new age 2020 state of malware report Social engineering attacks and covid-19 Chinese hackers 'weaponize' coronavirus data for new cyber attack: Here's what they did Coronavirus email attacks evolving as outbreak spreads Coronavirus phishing Threat Intel:Cyber Attacks Leveraging the COVID-19/CoronaVirus Pandemic Hackers are using the coronavirus fear for phishing, please pay attention to prevention Take advantage of the fire! Companies and verticals at risk for cyber attacks The implications of the COVID-19 pandemic for cybercrime policing in Scotland: a rapid review of the evidence and future considerations, ser.
    keywords: analysis; attacks; coronavirus; covid-19; crime; cyber; data; date; events; fraud; information; malware; pandemic; phishing; research; scams; security; threat; timeline
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        item: #512 of 7819
          id: cord-241686-bzt6jsyi
      author: Srivastava, Ambrish Kumar
       title: In Silico Investigations on the Potential Inhibitors for COVID-19 Protease
        date: 2020-03-24
       words: 1356
      flesch: 54
     summary: However, there exists no systematic study on the inhibition of the coronavirus by anti-malarial drugs to the best of our knowledge. Therefore, we believe that this study should offer better insights into the binding and interaction of anti-malarial drugs with the COVID-19 receptor.
    keywords: compounds; covid-19; log
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        item: #513 of 7819
          id: cord-242887-gtmpd7t0
      author: Bento, Ana I.
       title: Information Seeking Responses to News of Local COVID-19 Cases: Evidence from Internet Search Data
        date: 2020-04-06
       words: 1787
      flesch: 49
     summary: We highlight changes in search patterns occurring in the days leading up to and following first case announcements in a state (1,2). The second row shows searches for hand sanitizer increasing 35% immediately after first case announcements, and unlike in the previous two cases, the search activity remains high for the remainder of the observable period.
    keywords: announcements; case; covid-19; searches; state
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        item: #514 of 7819
          id: cord-243982-qhrlvmap
      author: Unberath, Mathias
       title: Artificial Intelligence-based Clinical Decision Support for COVID-19 -- Where Art Thou?
        date: 2020-06-05
       words: 2846
      flesch: 40
     summary: Another important component of any data infrastructure is the availability of clinical data in a standard form that can be shared in an anonymized manner across healthcare systems. AI is highly dependent on sufficiently diverse, representative data; AI/ML algorithms cannot be trained and adequately validated without creating large data sets that reflect the clinical use case, and such data will always be limited in the early phases of an emerging infectious disease.
    keywords: cds; covid-19; data; healthcare; pandemic; research; systems
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        item: #515 of 7819
          id: cord-246504-wjpi5uvz
      author: Pandey, Abhishek
       title: The effect of extended closure of red-light areas on COVID-19 transmission in India
        date: 2020-06-12
       words: 3871
      flesch: 40
     summary: Across India, extended closure of RLAs would benefit the population at large, delaying the peak of COVID-19 cases by 8 to 23 days, and avert 32% to 60.2% of cumulative cases and 43% to 67.6% of cumulative deaths at the peak of the epidemic. An analysis in Japan has demonstrated a surge of COVID-19 cases transmitted in RLAs-cases that have overwhelmed local hospitals 19 .
    keywords: cases; closure; covid-19; india; lockdown; peak; rlas; sex
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        item: #516 of 7819
          id: cord-246958-in0m5jnk
      author: Dharawat, Arkin
       title: Drink bleach or do what now? Covid-HeRA: A dataset for risk-informed health decision making in the presence of COVID19 misinformation
        date: 2020-10-17
       words: 4350
      flesch: 38
     summary: The covid-19 social media infodemic Misinformation of COVID-19 on the Internet: Infodemiology study CoAID: COVID-19 Healthcare Misinformation Dataset Towards detecting influenza epidemics by analyzing Twitter messages Bert: Pre-training of deep bidirectional transformers for language understanding Differences in health news from reliable and unreliable media Misinformation Battle Revisited: Counter Strategies from Clinics to Artificial Intelligence Online misinformation: Challenges and future directions Covid-19: the medium is the message Fake cures: user-centric modeling of health misinformation in social media Detecting influenza epidemics using search engine query data Examining patterns of influenza vaccination in social media Percent agreement, pearson's correlation, and kappa as measures of inter-examiner reliability Fact versus science fiction: fighting coronavirus disease 2019 requires the wisdom to know the difference Monitoring public health concerns using twitter sentiment classifications News verification by exploiting conflicting social viewpoints in microblogs Shot or not: Comparison of NLP approaches for vaccination behaviour detection Reappraising the utility of Google Flu Trends Assessment of reliability of youtube videos on orthodontics Convolutional Neural Networks for Sentence Classification Measuring emotions in the covid-19 real world worry dataset Google flu trends spatial variability validated against emergency department influenzarelated visits Coronavirus goes viral: These categories enable researchers to study the impact of coronavirus health misinformation at a finer granular level, to develop algorithms that caution the audience on the potential risks and to design systems that present unbiased information, i.e., both the original -potentially unreliable -post, along with any possible rebutting claims expressed online.
    keywords: category; covid-19; data; et al; health; media; misinformation; models; news
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        item: #517 of 7819
          id: cord-247059-uez654q2
      author: Alom, Md Zahangir
       title: COVID_MTNet: COVID-19 Detection with Multi-Task Deep Learning Approaches
        date: 2020-04-07
       words: 4715
      flesch: 54
     summary: For chest X-ray image analysis, due to the scarcity of publicly available COVID-19 X-ray samples, we have trained our model with a pneumonia dataset, and then utilized a Transfer Learning (TL) method for retraining with samples of COVID-19. The experimental results for the segmentation model for COVID-19 X-ray samples are shown in Figure 12 .
    keywords: chest; covid-19; detection; images; model; ray; samples
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        item: #518 of 7819
          id: cord-247554-535cpe5x
      author: Moustakas, Aristides
       title: Ranking the explanatory power of factors associated with worldwide new Covid-19 cases
        date: 2020-05-29
       words: 3585
      flesch: 41
     summary: The percentage of the total variance explained by each epidemiological, economic, public health, and governmental intervention variables associated with Covid-19 new cases was quantified using hierarchical variance partitioning [23, 24] thereby ranking the relative contribution of the variance of each factor on new Covid-19 cases worldwide. The best model fit regarding new Covid-19 cases per million and the economic status of the country where the new cases are recorded indicated that extreme poverty was a better predictor of new cases than gdp per capita.
    keywords: cases; covid-19; data; population; variables; variance
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        item: #519 of 7819
          id: cord-247879-jdkikd29
      author: Kayode, John Stephen
       title: The Covid-19 pandemic's effects on poor rural dwellers in sub-Saharan Africa: A case study of access to basic clean water, sanitary systems and hand-washing facilities
        date: 2020-06-08
       words: 5112
      flesch: 42
     summary: There has not been any confirmation so far of people contacting the coronavirus through water bodies, either in underground or surface waters, or spreading it through any contaminated drinking water system (Casanova, et al., 2020 , Shereen, et al., 2020 , Yang, et al., 2020 , despite the virus being detected in all types of water systems, with a reported connection between drinking and recreational water outbreaks. key: cord-247879-jdkikd29 authors: Kayode, John Stephen; Embrandiri, Asha; Olateju, Adijat Olubukola title: The Covid-19 pandemic's effects on poor rural dwellers in sub-Saharan Africa: A case study of access to basic clean water, sanitary systems and hand-washing facilities date: 2020-06-08 journal: nan DOI: nan sha: doc_id: 247879 cord_uid: jdkikd29
    keywords: covid-19; pandemic; people; region; ssan; systems; water
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        item: #520 of 7819
          id: cord-249065-6yt3uqyy
      author: Kassani, Sara Hosseinzadeh
       title: Automatic Detection of Coronavirus Disease (COVID-19) in X-ray and CT Images: A Machine Learning-Based Approach
        date: 2020-04-22
       words: 4295
      flesch: 40
     summary: The public dataset of X-ray images was provided by Dr. Joseph Cohen [22] investigated the diagnostic uncertainty and interpretability of deep learning-based methods for COVID-19 detection in X-ray images.
    keywords: accuracy; covid-19; dataset; deep; feature; images; learning; ray
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        item: #521 of 7819
          id: cord-249166-0w0t631x
      author: Booss-Bavnbek, Bernhelm
       title: Dynamics and Control of Covid-19: Comments by Two Mathematicians
        date: 2020-08-17
       words: 7251
      flesch: 58
     summary: In addition to various forms of influenza and the epidemics generated by the corona virus SARS-CoV-1, SARS-CoV-2 or MERS-CoV, other epidemics occurred. They became very influential because they displayed already many basic features that reappeared later in mathematical models of epidemics in other and more complex settings.
    keywords: cases; countries; covid-19; deaths; epidemic; health; number; population; sect; strategy; vaccine
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        item: #522 of 7819
          id: cord-249256-bd9j1din
      author: Cho, Jungwoo
       title: Running the COVID-19 marathon: the behavioral adaptations in mobility and facemask over 27 weeks of pandemic in Seoul, South Korea
        date: 2020-09-09
       words: 3711
      flesch: 42
     summary: Several recent studies also emphasized the need to understand behavioral aspects and perception changes regarding policy adherence 12 , and the importance of mobility data analyses for a broader understanding of the efficacy of public communication and social distancing interventions 13 . Hellewell et al. 11 stated that contact tracing and isolation without mobility reduction might not be sufficient to contain the outbreak under plausible scenarios.
    keywords: covid-19; data; day; epidemic; government; mobility; public; risk; study
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        item: #523 of 7819
          id: cord-249477-ux15lv31
      author: Darius, Philipp
       title: How the Far-Right Polarises Twitter: 'Highjacking' Hashtags in Times of COVID-19
        date: 2020-10-12
       words: 2747
      flesch: 44
     summary: Our findings indicate that polarisation of political party hashtags has not changed significantly in the last two years. The study is based on Twitter data that was collected by accessing Twitter's Rest API and using political party hashtags of German parties represented in the federal parliament (#AFD, #CDU, #CSU, #FDP, #GRUENE, #LINKE, #SPD) and COVID-19 related hashtags (#CoronaVirusDE and #FlattenThe-Curve) as a macro-level selection criterion.
    keywords: afd; covid-19; hashtags; partisans; polarisation; right
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        item: #524 of 7819
          id: cord-250374-y84dufy4
      author: Le'on, Ugo Avila-Ponce de
       title: A data driven analysis and forecast of an SEIARD epidemic model for COVID-19 in Mexico
        date: 2020-04-16
       words: 2042
      flesch: 49
     summary: Modeling COVID-19 epidemics in an Excel spreadsheet: Democratizing the access to first-hand accurate predictions of epidemic outbreaks Modeling and forecasting the Covid-19 pandemic in Brazil Chinese and Italian COVID-19 outbreaks can be correctly described by a modified SIRD model Dispersion of a new coronavirus SARS-CoV-2 by airlines in 2020: Temporal estimates of the outbreak in Mexico The construction of next-generation matrices for compartmental epidemic models Analysis and forecast of COVID-19 spreading in China, Italy and France Novel Coronavirus COVID-19 (2019-nCoV) Data Repository Mathematical modelling of the dynamics of the Coronavirus COVID-19 epidemic development in China A conceptual model for the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China with individual reaction and governmental action Age-structured impact of social distancing on the COVID-19 epidemic in India An updated estimation of the risk of transmission of the novel coronavirus (2019-nCov) Predicting COVID-19 distribution in Mexico through a discrete and time-dependent Markov chain and an SIR-like model The SARS-CoV-2 epidemic outbreak: a review of plausible scenarios of containment and mitigation for Mexico Hence Dead population D(t): Infected individuals with symptoms die at a rate δ, that is, dD dt = δI. Hence, the system of differential equations that will model the dynamics of coronavirus spread in Mexico is: We also observe that N :
    keywords: covid-19; individuals; model; population; rate
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        item: #525 of 7819
          id: cord-251581-8ubyveyt
      author: Szymkowiak, Andrzej
       title: In-store epidemic behavior: scale development and validation
        date: 2020-05-04
       words: 6042
      flesch: 44
     summary: This further indicates a more sophisticated need to measure what areas of consumer behaviors at stores are affected by the epidemic and therefore, the aim of the present study was an attempt to create such a measure. The developed scale can help counteract disinformation and assess consumer behavior compliance and understanding of the official recommendations imposed by governments, enabling more efficient educational efforts.
    keywords: consumers; covid-19; epidemic; infection; pandemic; research; respondents; scale; shopping; store; study; threat
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        item: #526 of 7819
          id: cord-251934-qi2c704c
      author: Raisi-Estabragh, Zahra
       title: Renin-Angiotensin-Aldosterone System Blockers Are Not Associated With Coronavirus Disease 2019 (COVID-19) Hospitalization: Study of 1,439 UK Biobank Cases
        date: 2020-07-14
       words: 3653
      flesch: 30
     summary: Database The relationship between metabolic risk factors and incident cardiovascular disease in Europeans, South Asians, and African Caribbeans: SABRE (Southall and Brent Revisited) -a prospective population-based study Ethnicity and COVID-19: an urgent public health research priority Greater risk of severe COVID-19 in Black, Asian and Minority Ethnic populations is not explained by cardiometabolic, socioeconomic or behavioural factors, or by 25(OH)-vitamin D status: study of 1326 cases from the UK Biobank Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York city area Clinical characteristics of Coronavirus Disease 2019 in China Sex-based differences in susceptibility to severe acute respiratory syndrome coronavirus infection Obesity impairs the adaptive immune response to influenza virus Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic Obesity a risk factor for severe COVID-19 infection: multiple potential mechanisms Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City. In this analysis of 7,099 UKB participants tested for COVID-19 in a hospital setting, BAME ethnicity, younger age, male sex, greater BMI, diabetes, hypertension, and smoking were independently associated with COVID-19 positive test in comparison to the rest of the cohort (tested negatives plus untested).
    keywords: acei; bmi; cardiometabolic; cohort; covid-19; ethnicity; patients; study
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        item: #527 of 7819
          id: cord-251945-v077hhgk
      author: Titanji, Boghuma K
       title: Response to Correspondence: Baricitinib as Treatment of COVID-19 Friend or Foe of the Pancreas? Cerda-Contreras et.al
        date: 2020-08-14
       words: 730
      flesch: 27
     summary: A c c e p t e d M a n u s c r i p t COVID-19 presenting as acute pancreatitis Coronavirus Disease-19 (COVID-19) associated with severe acute pancreatitis: Case report on three family members New-Onset Diabetes in Covid-19 Acute pancreatitis associated with intravenous administration of propofol: evaluation of causality in a systematic review of the literature Acute Pancreatitis Associated with Steroid Therapy Acute necrotising pancreatitis derived from lowdose corticosteroid use: an important reminder of clinical management Obesity is a definitive risk factor of severity and mortality in acute pancreatitis: An updated meta-analysis FRI0123 Safety profile of baricitinib for the treatment of rheumatoid arthritis up to 8.4 years: an updated integrated safety analysis COVID-19: combining antiviral and antiinflammatory treatments Glucocorticosteroids enhance replication of respiratory viruses: effect of adjuvant interferon Contrary to what is stated in their correspondence, acute pancreatitis has been described in several case reports as a manifestation of COVID-19 1,2 .
    keywords: covid-19; pancreatitis
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        item: #528 of 7819
          id: cord-251957-luw8m3eq
      author: Griffin, Claire L.
       title: Aortic Disease in the Time of COVID: Repercussions on Patient Care at an Academic Aortic Center
        date: 2020-04-30
       words: 1403
      flesch: 37
     summary: 2 We have addressed these challenges by modifying 5 our surgical indications and work flow to accommodate the constraints of this new environment 6 while continuing to provide appropriate and timely surgical care for patients with aortic disease. More data are needed to 17 evaluate this question as patients with concomitant COVID-19 and aortic disease are identified 18 and followed.
    keywords: aortic; covid-19; disease; patients
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        item: #529 of 7819
          id: cord-251959-3j4bqub4
      author: Jozaghi, Ehsan
       title: COVID-19 and people who use drugs: a call for action
        date: 2020-05-13
       words: 682
      flesch: 42
     summary: Such protective measures should include regular testing, access to handwashing stations, interactive warning signs, gloves, masks, self-isolation for outreach workers who are sick, and proper sanitizations of shared kitchens. Therefore, we urge the three levels of government: city, state/provincial and federal, and the non-profit housing agencies to implement protective measures in shelters, social housing facilities, remand, and outreach centres to protect vulnerable and marginalized populations.
    keywords: covid-19; measures; people
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        item: #530 of 7819
          id: cord-251961-g0n85kxz
      author: Li, Guoming
       title: Safety and efficacy of Artemisinin-Piperaquine for treatment of COVID-19: an open-label, non-randomized, and controlled trial
        date: 2020-11-02
       words: 3415
      flesch: 49
     summary: AP treatment did not cause TdP and other arrhythmias in the patients. Although AP treatment can cause the QT interval prolongation in some patients, it did not cause TdP and other arrhythmias.
    keywords: control; covid-19; days; group; patients; sars; treatment
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        item: #531 of 7819
          id: cord-251962-xeue441p
      author: Armour, Cherie
       title: The COVID-19 Psychological Wellbeing Study: Understanding the Longitudinal Psychosocial Impact of the COVID-19 Pandemic in the UK; a Methodological Overview Paper
        date: 2020-11-04
       words: 10295
      flesch: 46
     summary: In recognising this, a team of leading mental health scientists published a position paper detailing a number of mental health research priorities for the UK in response to the COVID-19 pandemic. These included the need for increased monitoring and reporting of the rates of mental health issues and a need to determine the factors that adversely or positively affect mental health during this time.
    keywords: covid-19; data; et al; health; pandemic; participants; research; sample; scale; study; survey; time; wellbeing
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        item: #532 of 7819
          id: cord-252013-ehyuflg3
      author: Bozzani, Antonio
       title: ACUTE ARTERIAL AND DEEP VENOUS THROMBOEMBOLISM IN COVID-19 PATIENTS
        date: 2020-09-22
       words: 2535
      flesch: 34
     summary: In particular, in relation to the known high incidence of DVT (25-31%) despite adequate prophylaxis 28 , we preferred to use an Istituto Superiore Sanità Italy Lessons learned during the COVID 19 virus pandemic Case-fatality rate and characteristics of patients dying in relation to COVID19 in Italy Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study The American College of Surgeons responds to COVID-19 Wick EC Rapid Response of an Academic Surgical Department to the COVID-19 Pandemic: Implications for Patients, Surgeons, and the Community Matthews CA Implementation Guide for Rapid Integration of an Outpatient Telemedicine Program During the COVID-19 Pandemic Disseminated Intravascular Coagulation and Thrombotic Microangiopathy-Either, Neither, or Both Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19 Online ahead of print Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia COVID-19: coagulopathy, risk of thrombosis, and the rationale for anticoagulation Risk assessment of venous thromboembolism and bleeding in COVID-19 patients Dying with SARS-CoV-2 infection-an autopsy study of the first consecutive Severe Acute Respiratory Syndrome Coronavirus 2 Infection and the Upper Limb Deep Vein Thrombosis Risk Acute limb ischemia in patients with COVID-19 pneumonia Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in china: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Pharmacologic treatments for coronavirus disease 2019 Mild or Moderate Covid-19 Lip GYH ying with SARS-CoV-2 infection-an autopsy study of the first consecutive Lip GYH; Global COVID-19 Thrombosis Collaborative Group Tissue plasminogen activator (tPA) treatment for COVID-19 associated acuete respiratory distress syndrome (ARDS): case series J o u r n a l P r e -p r o AIM: Our aim was to report the experience of the Department of Vascular Surgery of Pavia (Lombardy), including the lessons learned and future perspectives regarding the management of COVID-19 patients who developed severe acute ischemia with impending lower limb loss or deep vein thrombosis (DVT).
    keywords: acute; arterial; covid-19; patients; thrombosis
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        item: #533 of 7819
          id: cord-252015-9oiwcn8q
      author: Niu, Alex
       title: COVID-19 in allogeneic stem cell transplant: high false-negative probability and role of CRISPR and convalescent plasma
        date: 2020-06-15
       words: 1280
      flesch: 43
     summary: Ultrasensitive and high-throughput CRISPR-p owered COVID-19 diagnosis Compassionate Use of Remdesivir for Patients with Severe Covid-19 Remdesivir for the Treatment of Covid-19 -Preliminary Report Use of convalescent plasma therapy in SARS patients in Hong Kong Suppressed T cell-mediated immunity in patients with COVID-19: a clinical retrospective study in Wuhan Hypothesis for potential pathogenesis of SARS-CoV-2 infection-a review of immune changes in patients with viral pneumonia Treatment of 5 critically Ill patients with COVID-19 with convalescent plasma Identifier NCT04346199, Acalabrutinib Study With Best Supportive Care Versus Best Supportive Care in Subjects Hospitalized With COVID-19 The BTK inhibitor ibrutinib may protect against pulmonary injury in COVID-19-infected patients Acknowledgements We thank our patients for participating and donating the tissue samples to make this research possible. This poses the question of whether patients with objective findings consistent with COVID-19 and a negative nasopharyngeal RT-PCR assay would benefit from testing of other tissue types
    keywords: covid-19; patients; sars
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        item: #534 of 7819
          id: cord-252050-e71b15vg
      author: Wu, Jie
       title: Pharmacy services at a temporary COVID-19 hospital in Wuhan, China
        date: 2020-05-31
       words: 1152
      flesch: 28
     summary: Pharmacists at COVID-19 ark hospitals dispensed prescription drugs according to prescription administrative policy using the following procedures and workflow: (1) review prescription to determine whether the indication is suitable or not, the drugs selected are suitable or not, the routes of administration are suitable or not, the usage and dosage are suitable or not, the drug combination is suitable or not, and there is repeated administration or not; (2) dispense drugs on a first-in/first-out basis by batch number; (3) check the name, specification, and quantity of each drug; and (4) deliver the drugs to the nurse. Pharmacists in COVID-19 ark hospitals focused on the therapeutic and adverse effects of antiviral drugs through the following steps: (1) evaluate disease progression after treatment to confirm the effectiveness of drugs administrated; (2) monitor adverse drug reactions, especially in the aged, children, and patients with underlying diseases, and report adverse drug reactions; and (3) timely adjust the treatment plan to ensure the safety of medication use.
    keywords: ark; covid-19; drugs; hospitals
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        item: #535 of 7819
          id: cord-252084-04zbbyii
      author: Dawson, P.
       title: Loss of Taste and Smell as Distinguishing Symptoms of COVID-19
        date: 2020-05-16
       words: 1857
      flesch: 47
     summary: Nasal congestion alone is unlikely to explain the taste and smell alterations, as one-third of patients reporting loss of taste and/or smell did not report nasal congestion; other analyses have shown an even smaller proportion of COVID-19 cases with concurrent nasal congestion. Among the 64 household members of COVID-19 index cases, loss of taste and/or smell was reported by 12 individuals, of whom 10 were positive for SARS-CoV-2. for use under a CC0 license.
    keywords: loss; preprint; smell; taste
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        item: #536 of 7819
          id: cord-252149-0n58lec6
      author: Wang, Jiancong
       title: To relax restrictions: Are communities ready to deal with repeated epidemic waves of COVID-19?
        date: 2020-05-11
       words: 1100
      flesch: 42
     summary: Third, China implemented 'closed-off' management of residential communities. We learned the lesson of a rapid increase in the demand for the medical products during early outbreak, and these facilities will quickly meet the medical needs of the community as well as reduce the risk of community spread of the virus.
    keywords: cases; community; covid-19; health
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        item: #537 of 7819
          id: cord-252161-1ve7heyb
      author: Maulik, Pallab K.
       title: Roadmap to strengthen global mental health systems to tackle the impact of the COVID-19 pandemic
        date: 2020-07-29
       words: 3898
      flesch: 34
     summary: With shrinking economies, policy makers will have to rebalance prioritizing mental health services against other health service investments. Reports from Italy, underline how mental health services were prioritized in the face of the COVID pandemic by identifying essential mental health services, providing medications to those with substance use disorders, enabling teleconsultations
    keywords: care; covid-19; health; needs; pandemic; research; service; systems
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        item: #538 of 7819
          id: cord-252244-y5w9hjy8
      author: Loeffler-Wirth, H.
       title: Covid-19 trajectories: Monitoring pandemic in the worldwide context
        date: 2020-06-05
       words: 7925
      flesch: 44
     summary: Comparative analysis between trajectories of different countries enables to judge different scenarios of NPIs, population size, and social factors. The paper is organized as follows: In the results section we introduce and illustrate the different trajectories and plots available in the monitoring tool by showing examples from different countries of the world, which are thought to serve as worked examples referring to the actual state of pandemic in the second half of May 2020.
    keywords: cases; countries; covid-19; epidemic; figure; license; medrxiv; numbers; preprint; rate; trajectories; transmission
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        item: #539 of 7819
          id: cord-252251-ji45igni
      author: Yannouchos, T.
       title: Characteristics and risk factors for COVID-19 diagnosis and adverse outcomes in Mexico: an analysis of 89,756 laboratory-confirmed COVID-19 cases
        date: 2020-06-05
       words: 3868
      flesch: 44
     summary: Differences among COVID-19 patients based on two separate clinical endpoints, hospitalization and adverse outcome, were examined. COVID-19 patients were disproportionately older, males and with increased prevalence of one or more comorbidities, particularly diabetes, obesity, and hypertension.
    keywords: covid-19; license; medrxiv; patients; perpetuity; preprint
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        item: #540 of 7819
          id: cord-252273-mykwzlsu
      author: Politis, Constantina
       title: Post-donation information and haemovigilance reporting for COVID-19 in Greece: information supporting the absence of SARS-CoV-2 possible transmission through blood components
        date: 2020-10-20
       words: 1684
      flesch: 43
     summary: Haemovigilance provided information supporting the absence of transfusion transmission of COVID-19, thus strengthening the hypothesis that, even if it cannot yet be definitively ruled out, COVID-19 is not transmitted through blood transfusion. Due to the urgent requirement for blood, it remains critically important to know whether the COVID-19 virus can be transmitted by blood transfusion, because asymptomatic carriers may donate blood and therefore blood donation could be an unidentified route of transmission.
    keywords: blood; coronavirus; covid-19; transfusion; transmission
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        item: #541 of 7819
          id: cord-252279-0gozdv43
      author: Pal, Amit
       title: Hydroxychloroquine and Covid-19: A Cellular and Molecular Biology Based Update
        date: 2020-06-10
       words: 3866
      flesch: 31
     summary: Notably, in a mouse model of antiphospholipid syndrome, hydroxychloroquine treatment was associated with improvement in endothelial function [69, 70] . The exact molecular mechanisms by which DMARD hydroxychloroquine drug mediate their antithrombotic effects remain largely unknown and lay the platform for future prospective studies.
    keywords: cov-2; covid-19; disease; drugs; hydroxychloroquine; patients; sars; studies; syndrome; treatment; use
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        item: #542 of 7819
          id: cord-252284-cgdcsazr
      author: Zeng, Jia-Hui
       title: First case of COVID-19 complicated with fulminant myocarditis: a case report and insights
        date: 2020-04-10
       words: 1991
      flesch: 44
     summary: Lancet. 2020 Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Chinese society of cardiology expert consensus statement on the diagnosis and treatment of adult fulminant myocarditis An experimental model for myocarditis and congestive heart failure after rabbit coronavirus infection Laboratory-confirmed respiratory infections as predictors of hospital admission for myocardial infarction and stroke: timeseries analysis of English data for A followup study of 69 discharged SARS patients Acute myocarditis associated with novel Middle east respiratory syndrome coronavirus Pathological findings of COVID-19 associated with acute respiratory distress syndrome Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology An interferon-gamma-related cytokine storm in SARS patients Intermittent hypoxia causes inflammation and injury to human adult cardiac myocytes Prognostic value of electrocardiography in patients with fulminant myocarditis supported by percutaneous venoarterial extracorporeal membrane oxygenation-analysis from the CHANGE PUMP study Acknowledgements We thank the patient for granting us permission All available information is contained within the manuscript. COVID-19 patients may develop severe cardiac complications such as myocarditis and heart failure.
    keywords: covid-19; heart; infection; myocarditis; patient; pneumonia
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        item: #543 of 7819
          id: cord-252306-68eogdyc
      author: Adler, Hugh
       title: Low rate of bacterial co-infection in patients with COVID-19
        date: 2020-06-30
       words: 505
      flesch: 26
     summary: By contrast, in influenza infection the prevalence of bacterial coinfection in hospitalised patients can exceed 30%. Hospital policy for patients admitted with community-acquired pneumonia, including suspected COVID-19 cases, recommends blood cultures and pneumococcal and Legionella urinary antigen tests based on clinical severity, in line with national guidelines.
    keywords: covid-19; patients
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        item: #544 of 7819
          id: cord-252328-ov4r3ple
      author: Ortoleva, Jamel
       title: Consider Adjunctive Ketamine in Mechanically Ventilated COVID-19 Patients
        date: 2020-04-28
       words: 483
      flesch: 29
     summary: 2 Another important cause which is frequently present with ARDS is cytokine storm can result in vasodilatory shock and multiorgan dysfunction. The hyperinflammation associated with cytokine storm is similar to that found in secondary haemophagocytic lymphohistiocytosis (HLH).
    keywords: ketamine; patients
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        item: #545 of 7819
          id: cord-252343-a85wz2hs
      author: Skoda, Eva-Maria
       title: Psychological burden of healthcare professionals in Germany during the acute phase of the COVID-19 pandemic: differences and similarities in the international context
        date: 2020-08-07
       words: 2923
      flesch: 47
     summary: High psychological burden of front-line workers could be found in China 4-6,26 and other countries (e.g. Tan et al . 3 ). Subjective levels of information regarding COVID-19 correlated negatively with generalized anxiety levels across all groups.
    keywords: anxiety; burden; covid-19; hps; information; levels
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        item: #546 of 7819
          id: cord-252374-obl6pfpf
      author: Zaninotto, Martina
       title: Cardiac troponin I in SARS-CoV-2-patients: the additional prognostic value of serial monitoring
        date: 2020-10-01
       words: 2962
      flesch: 22
     summary: Aim of our study has been to investigate in COVID-19 patients the kinetics of release of cardiac troponin I and time course of its concentrations, measured with a high-sensitivity method (hs-TnI), in order to verify if serial measurements may provide additional and clinically useful information in identifying the underlying mechanisms of release and patients' risk stratification and prognosis. A review of typical CT findings and differential diagnosis Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients Myocardialinjury and COVID-19: Possible mechanisms Myocarditis in a patient with COVID-19: a cause of raised troponin and ECG changes High-sensitivity troponin I and incident coronary events, stroke, heart failure hospitalization, and mortality in the Atherosclerosis Risk in Communities (ARIC) study Association of repeatedly measured high-sensitivity-assayed troponin I with cardiovascular disease events in a general population from the MORGAM/BiomarCaRE Study Quantifying the Release of Biomarkers of Myocardial Necrosis From Cardiac Myocytes and Intact Myocardium ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC) Long-term outcomes in patients with type 2 myocardial infarction and myocardial injury COVID-19 and cardiovascular disease Impact of cardiovascular disease and cardiac injury on in-hospital mortality in patients with COVID-19: a systematic review and meta-analysis Association of coronavirus disease 2019 (covid-19) with myocardial injury and mortality Cardiac troponin for the diagnosis and risk-stratification of myocardial injury in COVID-19: JACC Review Topic of the Week Sample CRediT author statement Paper CCACTA-D-20-01705 Cardiac troponin I in SARS-CoV-2-patients: the additional prognostic value of serial monitoring conceptualization, methodology, data curation, writing, validation Males, n (%); Females, n (%) 80 Laboratory Findings (Table 1B) Biomarker, measuring unit (Reference Interval) White-cell count, 10 9 /L
    keywords: cardiac; covid-19; ctni; disease; patients; troponin
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        item: #547 of 7819
          id: cord-252389-xrdbmosj
      author: Kumar, Mukesh
       title: Neurological manifestations and comorbidity associated with COVID-19: an overview
        date: 2020-10-14
       words: 5453
      flesch: 37
     summary: The neurological manifestations reported by SARS patients, SARS-CoV was detected in samples/specimens of SARS patients. In this article, we have reviewed the neurological characteristic features of COVID-19 patients, latent neurotropic mechanisms of SARS-CoV-2 involvement in the comorbidity associated with CNS disorders, and neurological manifestations associated with COVID-19.
    keywords: brain; cns; coronavirus; cov-2; covid-19; disease; infection; manifestations; patients; sars; symptoms
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        item: #548 of 7819
          id: cord-252400-fdi132vi
      author: Qiu, Liru
       title: A Case of Critically Ill Infant of Coronavirus Disease 2019 With Persistent Reduction of T Lymphocytes
        date: 2020-04-16
       words: 2203
      flesch: 45
     summary: Lopinavir/ritonavir (12.5/3.125 mg/kg, twice daily) was introduced on the evening of hospitalization day 7 (illness day 13), followed by a second dose of intravenous immune globulin (1 mg/kg·d, hospitalization days 8-9, illness days 14-15), methylprednisolone (2 mg/ kg·d, hospitalization days 8-14, illness days 14-20 days, tapering) ( Table 1 ). The percentage of CD3+CD4+CCR7−CD45RA− lymphocytes was 53.13% (in CD4+ T cells) despite sustained reduction of CD3+, CD4+ and CD8+ lymphocytes (Table S4, Because critically ill pediatric cases with COVID-19 are unusual, little is known about the characteristics in this age group with such severity of illness.
    keywords: cd4; covid-19; day; infant
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        item: #549 of 7819
          id: cord-252416-d244rl65
      author: Gomes, Bruno de Araujo
       title: In-House Three-Dimensional Printing Workflow for Face Shield During COVID-19 Pandemic
        date: 2020-07-03
       words: 1398
      flesch: 45
     summary: Within this context, the present work seeks to present an alternative for the production of face shields “face shields,” in which it recommends its production “in house” through 3D printing, in principle initiated by Prusa Research, where we download your project of support of facial protectors, proceeding with printing through the 3D printer Gtmax3D 6, 7 In recent years, 3D printing has achieved rapid popularity in the dental field, due to the varied possibilities of using this technology, mainly due to its increased precision and printing speed.
    keywords: covid-19; face; printing; use
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        item: #550 of 7819
          id: cord-252423-ojmt4k2w
      author: Qu, Bing
       title: Monologue of a physician who tested persistently positive for COVID-19
        date: 2020-05-11
       words: 1102
      flesch: 67
     summary: 1 Similar to other COVID-19 patients, I had dry cough, fever, body aches, and fatigue during the first week. This new group of patients have brought new challenge to COVID-19 treatment.
    keywords: covid-19
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        item: #551 of 7819
          id: cord-252434-7g69amr1
      author: Lu, Xiao
       title: Therapeutic effect of high-flow nasal cannula on severe COVID-19 patients in a makeshift intensive-care unit: A case report
        date: 2020-05-22
       words: 2552
      flesch: 43
     summary: The main clinical manifestation of respiratory failure in COVID-19 patients is hypoxemia accompanied by labored breathing. HFNC treatment has its advantages in providing oxygen therapy in COVID-19, but healthcare professionals should still pay close attention to changes in patients’ oxygenation rates and respiratory frequency.
    keywords: covid-19; flow; hfnc; oxygen; patients; treatment
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        item: #552 of 7819
          id: cord-252506-8u9oiqoc
      author: Scarfò, Lydia
       title: COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus
        date: 2020-07-09
       words: 4025
      flesch: 33
     summary: A novel coronavirus from patients with pneumonia in China Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Early detection of SARS-CoV-2 antibodies in COVID-19 patients as a serologic marker of infection Clinical and immunological features of severe and moderate coronavirus disease 2019 Weathering the COVID-19 storm: lessons from hematologic cytokine syndromes Clinical characteristics and outcomes of hospitalised patients with COVID-19 treated in Hubei (epicenter) and outside Hubei (nonepicenter): a nationwide analysis of China COVID-19 in persons with haematological cancers Clinical characteristics, outcomes, and risk factors for mortality in patients with cancer and COVID-19 in Hubei, China: a multicentre, retrospective, cohort study Patients with cancer appear more vulnerable to SARS-CoV-2: a multicenter study during the COVID-19 outbreak Clinical characteristics and risk factors associated with COVID-19 disease severity in patients with cancer in Wuhan, China: a multicentre, retrospective, cohort study Survival study of hospitalised patients with concurrent COVID-19 and haematological malignancies CLL and COVID-19 at the Hospital Clinic of Barcelona: an interim report COVID-19 in a patient with chronic lymphocytic leukaemia Perturbation of the normal immune system in patients with CLL T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production Immunomodulatory effect of ibrutinib: reducing the barrier against fungal infections The BTK inhibitor ibrutinib may protect again pulmonary injury in COVID-19-infected patients Chronic lymphocytic leukemia management in italy during the COVID-19 Pandemic. The presence of three or more comorbidities was not significantly different in patients hospitalized with severe versus nonsevere disease; moreover, the presence of hypogammaglobulinemia, a frequent laboratory finding in CLL, did not show a relevant impact on the clinical course of COVID-19 patients, probably underscoring the relevance of the inflammatory reaction rather than the viral replication (and the capacity to clear it by antibody-mediated immune response) in shaping the severity of the disease.
    keywords: cases; cll; cov-2; covid-19; disease; patients; sars; study; treatment
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        item: #553 of 7819
          id: cord-252513-zwdy1h7j
      author: Kiely, Daniel J.
       title: Health care team training and simulation-based education in obstetrics during the COVID-19 pandemic
        date: 2020-05-30
       words: 1339
      flesch: 30
     summary: We propose four broad categories of social distancing which, alone or in combination, may allow healthcare team simulation training to continue. There is accumulating evidence that simulation training in healthcare improves patient outcomes.
    keywords: covid-19; pandemic; simulation; training
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        item: #554 of 7819
          id: cord-252528-rgnhfcbx
      author: Du, Fenghe
       title: COVID-19: the role of excessive cytokine release and potential ACE2 down-regulation in promoting hypercoagulable state associated with severe illness
        date: 2020-07-16
       words: 8450
      flesch: 24
     summary: Besides the enhanced levels of pro-inflammatory cytokines, increased plasma levels of anti-inflammatory cytokines, including IL-10, have been simultaneously detected in COVID-19 patients, suggesting a dysregulation of the adaptive immune system following the virus infection [2] . Furthermore, ACEI reduces levels of pro-inflammatory cytokine expressions in the aorta in patients with abdominal aortic aneurysm, indicating the ability of ACEI to reduce vascular inflammation [102] .
    keywords: ace2; anti; cells; cov-2; covid-19; cytokine; ifn; il-6; infection; levels; patients; release; sars; serum; vascular
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        item: #555 of 7819
          id: cord-252531-i3b647wv
      author: Song, Zaiwei
       title: Hospital pharmacists’ pharmaceutical care for hospitalized patients with COVID-19: Recommendations and guidance from clinical experience
        date: 2020-04-03
       words: 3542
      flesch: 27
     summary: Based on the Chinese perspective of centralizing COVID-19 patients and centralized inpatient treatment, the paper established a pharmaceutical care framework of COVID-19 hospitalized patients, including participating in making evidence-based decisions for medication, monitoring and evaluation of medication safety and efficacy, strengthened care for special population and patients with combined underlying diseases, monitoring and management of convalescent plasma therapy (CPT), providing emotional counselling and psychological support and providing scientific information about COVID-19 vaccines. Based on the Chinese perspective of centralizing COVID-19 patients and centralized inpatient treatment, the purpose of the paper is to establish an integrated strategy for pharmaceutical care services, which focus on COVID-19 hospitalized patients and hospital pharmacists.
    keywords: care; covid-19; drugs; hospital; patients; pharmaceutical; pharmacists; treatment
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        item: #556 of 7819
          id: cord-252557-f89m6xv5
      author: Ong, John
       title: Prevention of nosocomial SARS-CoV-2 transmission in endoscopy: international recommendations and the need for a gold standard
        date: 2020-04-02
       words: 1302
      flesch: 39
     summary: 2 3 Singapore previously had the largest cohort of COVID-19 patients outside China in the early phases of the outbreak. High risk=symptomatic with either contact risk of from the high-risk area.
    keywords: covid-19; endoscopy; patients; risk; sars
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        item: #557 of 7819
          id: cord-252616-aobuhwbi
      author: Dalla Costa, Gloria
       title: Real-time assessment of COVID-19 prevalence among multiple sclerosis patients: a multicenter European study
        date: 2020-07-02
       words: 1736
      flesch: 39
     summary: Through the ongoing remote monitoring of MS patients in Electronic supplementary material The online version of this article (https://doi.org/10.1007/s10072-020-04519-x) contains supplementary material, which is available to authorized users. Italy, Spain, and Denmark, we aimed to explore the prevalence and impact of the current pandemic among MS patients across Europe. Using different case definitions, the percentage of MS patients with symptoms suggestive of infection varied between 9 and 13%.
    keywords: case; covid-19; monitoring; patients; symptoms
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        item: #558 of 7819
          id: cord-252661-wa0hdg1u
      author: Pennington, Zach
       title: Letter: Changes to neurosurgery resident education following onset of the COVID-19 pandemic
        date: 2020-05-22
       words: 4248
      flesch: 36
     summary: As residents must meet minimum case volumes to demonstrate proficiency 5 upon program completion, 3 there is concern among both residents and program directors 6 regarding the severity of the impact of COVID-19 on neurosurgical resident education. Ammar et al noted similar effects in their report 283 on efforts to maintain wellness amongst neurosurgical residents at a New York City program.
    keywords: changes; covid-19; education; lectures; neurosurgery; pandemic; programs; resident; wellness
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        item: #559 of 7819
          id: cord-252664-h02qy4z0
      author: Kontis, V.
       title: Age- and sex-specific total mortality impacts of the early weeks of the Covid-19 pandemic in England and Wales: Application of a Bayesian model ensemble to mortality statistics
        date: 2020-05-25
       words: 5886
      flesch: 57
     summary: The models account for seasonality of death rates, medium-long-term trends in death rates, the impact of temperature on death rates, association of death rates in each week on those in preceding week(s), and the impact of bank holidays. We used data from January 2010 through mid-February 2020 (i.e., week starting 15th February 2020) to estimate the parameters of each model, which was then used to predict the number of deaths for subsequent weeks as estimates of death rates if the pandemic had not occurred.
    keywords: age; covid-19; deaths; mortality; pandemic; preprint q; q q; years
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        item: #560 of 7819
          id: cord-252687-7084pfqm
      author: Szelenberger, Rafal
       title: Ischemic Stroke among the Symptoms Caused by the COVID-19 Infection
        date: 2020-08-19
       words: 7350
      flesch: 34
     summary: Despite the available clinical studies evaluating the potential role of hemostatis biomarkers (i.e., von Willebrand factor (vWF), P-selectin, fibrinogen, thrombomodulin, tissue factor, d-dimer, etc.) in ischemic stroke patients, the value of studied biomarkers is still unproven and requires further investigation [26] . Ischemic stroke patients mostly received thrombolytic therapy.
    keywords: acute; blood; brain; cells; coagulation; coronavirus; cov-2; covid-19; endothelium; infection; ischemic; patients; response; sars; stroke; symptoms; system
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        item: #561 of 7819
          id: cord-252694-36ijqwge
      author: Heidinger, Benedikt H.
       title: Radiologische Manifestationen von Lungenerkrankungen bei COVID-19
        date: 2020-09-08
       words: 2968
      flesch: 35
     summary: Besteht jedoch der Verdacht auf eine im Rahmen von COVID-19 gehäuft auftretende Pulmonalembolie, sollte eine kontrastmittelunterstützte CT in pulmonalarterieller Phase durchgeführt werden Die schwerste Form der Lungenbeteiligung im Rahmen von COVID-19 manifestiert
    keywords: auf; bei; chest; covid-19; der; die; disease; einer; imaging; ist; mit; oder; patienten; patients; pcr; pneumonia; sich; und; von
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        item: #562 of 7819
          id: cord-252699-0xw9xvox
      author: de Marcaida, Joy Antonelle
       title: Clinical Characteristics of Coronavirus Disease 2019 (COVID-19) among Patients at a Movement Disorders Center
        date: 2020-09-18
       words: 3440
      flesch: 36
     summary: On the other hand, Antonini and colleagues reported on the outcomes of 10 PD patients affected by COVID-19 at the Parkinson and Movement Disorders unit in Italy and at King's College Hospital in London, and suggested that PD patients, particularly those who are older and on advanced therapies, should be considered as a specifically susceptible group because of the high mortality rate noted for this subset of patients in their series [15] . Impact of the COVID-19 Pandemic on Parkinson's Disease and Movement Disorders The impact of the COVID-19 pandemic on Parkinson's disease: Hidden sorrows and emerging opportunities COVID-19: An Early Review of Its Global Impact and Considerations for Parkinson's Disease Patient Care The effect of frailty on survival in patients with COVID-19 (COPE): A multicentre, European, observational cohort study Multimorbidity and Frailty: Tackling Complexity in Parkinson's Disease SARS-CoV-2: At the Crossroad Between Aging and Neurodegeneration COVID-19 and Parkinson's Disease: Are We Dealing with Short-term Impacts or Something Worse? Parkinson's Disease and COVID-19: Perceptions and Implications in Patients and Caregivers Effects of COVID-19 on Parkinson's Disease Clinical Features: A Community-Based Case-Control Study Outcome of Parkinson's Disease Patients Affected by COVID-19 Clinical Presentation of COVID19 in Dementia Patients Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: Prospective observational cohort study Neurologic Manifestations of Hospitalized Patients with Coronavirus Disease Neurological manifestations and complications of COVID-19:
    keywords: covid-19; disease; disorders; movement; parkinson; patients
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        item: #563 of 7819
          id: cord-252703-00ks1j0x
      author: Keddy, Karen H
       title: Developing health policies in patients presenting with SARS-CoV-2: consider tuberculosis
        date: 2020-10-15
       words: 963
      flesch: 31
     summary: Any symptomatic patient presenting with presumptive COVID-19 from a population at a high risk for tuberculosis, or from a country in which tuberculosis is highly endemic, 4 should have both diseases considered when it comes to submitting specimens for diagnosis, because of the potential reactivation of latent tuberculosis caused by the presence of SARS-CoV-2, or the greater frequency of tuberculosis presenting as community-acquired pneumonia in those populations. A clear policy integrating diagnostics and care for both diseases will ensure that tuberculosis programmes are not disrupted in COVID-19 control efforts, but rather enhance tuberculosis diagnosis and control.
    keywords: covid-19; disease; tuberculosis
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        item: #564 of 7819
          id: cord-252714-idlyl4ga
      author: Islam, M. Saiful
       title: Current knowledge of COVID-19 and infection prevention and control strategies in healthcare settings: A global analysis
        date: 2020-05-15
       words: 5670
      flesch: 45
     summary: To identify COVID-19 IPC guidelines, we visited the websites of the international public health agencies such as CDC, ECDC, WHO, as well as the Australian Government Department of Health, the Bureau of Disease Prevention and Control of the National Health Commission of the People's Republic of China, and Public Health England. For example, blood, saliva, and stool, of COVID-19 patients have been tested positive for SARS-CoV-2, 60,63,69 but the precise role these body fluids play in disease transmission in healthcare settings and the ways in which they may be transferred remain uncertain.
    keywords: control; coronavirus; cov-2; covid-19; guidelines; hcps; health; infection; ipc; patients; prevention; sars; transmission
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        item: #565 of 7819
          id: cord-252721-vy6tfer4
      author: Purnama, T. B.
       title: How to handle the deceased body of COVID-19: an insight from Indonesian muslim burial handlers knowledge, perception, and practice
        date: 2020-08-07
       words: 1917
      flesch: 51
     summary: A qualitative study was employed to explore knowledge, perception, and practice among muslim burial handlers on burial rites in COVID-19 cases. In our study found that lack of information and personal protective equipment in the burial rites Muslim burial handlers did not get relevant information related to how to process burial rites in accordance with health and religious procedures.
    keywords: burial; community; covid-19; preprint
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        item: #566 of 7819
          id: cord-252725-e3pazjdi
      author: Khalil, Ayman
       title: The upshot of Polyphenolic compounds on immunity amid COVID-19 pandemic and other emerging communicable diseases: An appraisal
        date: 2020-10-15
       words: 8801
      flesch: 31
     summary: Polydatin has numerous benefits which is widely reported including anti-inflammatory effect in chronic lung diseases, anti-oxidative, anti-platelet aggregative, anti-fibrosis, anti-cancer, benefits for neurological diseases and anxiolytic effects [207, 208] . Anti-asthmatic activity of luteolin was also reported in experimental mice [93] .
    keywords: acid; activities; activity; anti; antioxidant; compounds; covid-19; diseases; effects; fig; human; infection; inflammation; influenza; lung; respiratory; sars; virus; vitro
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        item: #567 of 7819
          id: cord-252726-t5tcp6di
      author: Cheong, Mark Wing Loong
       title: COVID‐19 and Clinical Pharmacy Worldwide ‐ A Wake Up Call and a Call to Action
        date: 2020-06-15
       words: 2066
      flesch: 37
     summary: Despite being ordered out of the wards and asked to focus on the supply chain, many clinical pharmacists have found ways to continue contributing to patient care and the quality use of medicines. The American College of Clinical Pharmacy (ACCP) has previously described tasks common to clinical pharmacists in the U.S.(8)
    keywords: care; covid-19; health; pharmacists; pharmacy; services
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        item: #568 of 7819
          id: cord-252727-9v2zr75m
      author: Henry, Brandon Michael
       title: Red Blood Cell Distribution Width (RDW) Predicts COVID-19 Severity: A Prospective, Observational Study from the Cincinnati SARS-CoV-2 Emergency Department Cohort
        date: 2020-08-21
       words: 3447
      flesch: 33
     summary: Moreover, our findings are in agreement with other data published in patients with other forms of ARDS not attributable to SARS-CoV-2 infection [17] , as well as in an earlier publication on COVID-19 patients, characterized by a different setting and patient cohort. More specifically, the authors of this investigation found that circulating erythrocytes of COVID-19 patients displayed substantially enhanced expression of glycolytic intermediates, combined with significant degree of oxidative damages and consequent fragmentation of proteins such as spectrin beta, ankyrin, and N-terminal cytosolic domain of band 3 (AE1).
    keywords: blood; covid-19; disease; patients; prognostic; rdw; severity; study
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        item: #569 of 7819
          id: cord-252745-qhhziz0u
      author: Gheysarzadeh, Ali
       title: Report of four pregnant women getting COVID-19 in Ilam, Iran: Case Series
        date: 2020-10-13
       words: 1030
      flesch: 55
     summary: Conclusion This study showed although pregnant women were at higher risk of COVID-19 infection, they were treated successfully. Pregnant women are determined as one of the high-risk groups.
    keywords: covid-19; infection; women
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        item: #570 of 7819
          id: cord-252771-6kwfulqe
      author: Yue, Jing-Li
       title: Mental health services for infectious disease outbreaks including COVID-19: a rapid systematic review
        date: 2020-11-05
       words: 7946
      flesch: 29
     summary: We sought to include any articles focusing on mental health interventions or services applied specifically for infectious disease outbreaks. Except for publications on some mental health intervention systems and psychosocial interventions, most other reports were not specifically designed to evaluate the feasibility and effectiveness of mental health interventions.
    keywords: care; china; covid-19; depression; disease; et al; health; healthcare; interventions; outbreak; pandemic; patients; review; risk; services; support; workers
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        item: #571 of 7819
          id: cord-252775-faxiem2w
      author: Tamagnini, Gabriele
       title: Cardiac surgery in the time of the novel coronavirus: Why we should think to a new normal
        date: 2020-07-15
       words: 1724
      flesch: 33
     summary: http://orcid.org/0000-0003-0592-6585 Joseph Lamelas http://orcid.org/0000-0003-1570-1988 Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72, 314 cases from the Chinese center for disease control and prevention Cardiac involvement in COVID-19 patients: risk factors, predictors, and complications: a review COVID-19 Myocarditis and Severity Factors: An Adult Cohort Study Cardiovascular implications of fatal outcomes of patients with coronavirus disease Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) -China Trias-Llimos S Population age structure only partially explains the large number of COVID-19 deaths at the oldest ages At the heart of COVID-19 COVID-19 and multiorgan response Prevalence of underlying diseases in hospitalized patients with COVID-19: a systematic review and meta-analysis An acute respiratory infection runs into the most common noncommunicable epidemic-COVID-19 and cardiovascular diseases Epidemiology of acquired valvular heart disease Aortic stenosis in the elderly: disease prevalence and number of candidates for transcatheter aortic valve replacement: a meta-analysis and modeling study Isolated aortic valve replacement in North America comprising 108,687 patients in 10 years: changes in risks, valve types, and outcomes in the Society of Thoracic Surgeons National Database Heart Surgery Report 2018: the Annual Updated Registry of the German Society for Thoracic and Cardiovascular Surgery COVID-19 pandemic and cardiac imaging: We have to be prepared to preserve the safety of health care workers and hospital admitted patients, while having dedicated OR, ICU, and ward beds to treat COVID-19 patients: Indeed, the access to a proper and timely treatment cannot depend on the outcome of a swab.
    keywords: age; covid-19; diseases; patients; surgery
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        item: #572 of 7819
          id: cord-252783-iw3hgkpj
      author: Risch, Harvey A
       title: Response to: Comment on “Early Outpatient Treatment of Symptomatic, High-Risk Covid-19 Patients That Should be Ramped-Up Immediately as Key to the Pandemic Crisis”
        date: 2020-07-20
       words: 338
      flesch: 27
     summary: Early Outpatient Treatment of Symptomatic, High-Risk Covid-19 Patients That Should be Ramped-Up Immediately as Key to the Pandemic Crisis Early outpatient treatment of symptomatic, high-risk Covid-19 patients that should be ramped-up immediately as key to the pandemic crisis Early treatment of 1061 COVID-19 patients with hydroxychloroquine and azithromycin Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Outcomes of 3,737 COVID-19 patients treated with hydroxychloroquine/azithromycin and other regimens in Marseille, France: a retrospective analysis However, the tested Marseille subjects were all self-referred individuals, many from lower socioeconomic strata or recent immigrants, mostly with disease symptoms or known to have had exposure to people with symptoms, and their 152/1,061=14% conventional unit hospitalization suggests that at least this number would have been at high risk.
    keywords: covid-19
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        item: #573 of 7819
          id: cord-252784-wfsq0u9o
      author: Favot, Mark
       title: Point-of-Care Lung Ultrasound for Detecting Severe Presentations of Coronavirus Disease 2019 in the Emergency Department: A Retrospective Analysis
        date: 2020-07-31
       words: 4101
      flesch: 37
     summary: The NDBPE pattern was chosen based on the hypothesis that COVID-19 LUS findings may be similar to those seen in acute respiratory distress syndrome (ARDS). A follow-up study examining this phenomenon in COVID-19 patients would be prudent.
    keywords: covid-19; edema; lung; lus; patients; ultrasound
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        item: #574 of 7819
          id: cord-252795-x66zqmgv
      author: Islam, Md. Akhtarul
       title: Depression and anxiety among university students during the COVID-19 pandemic in Bangladesh: A web-based cross-sectional survey
        date: 2020-08-26
       words: 4014
      flesch: 41
     summary: Tanvir title: Depression and anxiety among university students during the COVID-19 pandemic in Bangladesh: A web-based cross-sectional survey date: 2020-08-26 journal: PLoS One DOI: 10.1371/journal.pone.0238162 sha: doc_id: 252795 cord_uid: x66zqmgv The purpose of this study was to investigate the prevalence of depression and anxiety among Bangladeshi university students during the COVID-19 pandemic. It is expected that both the government and universities could work together to fix the academic delays and financial problems to reduce depression and anxiety among university students.
    keywords: anxiety; covid-19; depression; health; mental; students; study; university
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        item: #575 of 7819
          id: cord-252799-p2ulrnsi
      author: Ying-Ying Wong, Ashley
       title: Impact of the COVID-19 pandemic on sports and exercise
        date: 2020-07-28
       words: 1651
      flesch: 43
     summary: Infection Prevention in Practice Potential impact of physical activity and sport on the immune system--a 343 brief review Immunity in athletes Exercise, immune function and respiratory infection: An update on the 350 influence of training and environmental stress Exercise and Immune Function: Recent Developments. We performed a laboratory study to investigate the physiological effect of wearing a facemask during simulated hiking and found that it significantly elevated heart rate and perceived exertion.
    keywords: coronavirus; covid-19; exercise; infection; kong; rate
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        item: #576 of 7819
          id: cord-252800-cz4mb3wx
      author: Smith, Timothy L.
       title: COVID‐19 – Looking beyond the immediate concerns
        date: 2020-05-12
       words: 640
      flesch: 57
     summary: key: cord-252800-cz4mb3wx authors: Smith, Timothy L. title: COVID‐19 – Looking beyond the immediate concerns date: 2020-05-12 journal: Int Forum Allergy Rhinol DOI: 10.1002/alr.22583 sha: doc_id: 252800 cord_uid: cz4mb3wx nan I sit at my desk on Friday, March 20, 2020, having finished one of the busiest work weeks I can recall and most definitely the busiest work week in which I felt like I did not accomplish anything, at least as measured by my typical metrics. Even after the pandemic comes under control, we will need to continue to prioritize operating theater time equitably to those with the most severe and urgent disease processes.
    keywords: covid-19; pandemic
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        item: #577 of 7819
          id: cord-252804-u7tz6xzz
      author: Ciotti, Marco
       title: COVID-19 Outbreak: An Overview
        date: 2020-04-07
       words: 3571
      flesch: 45
     summary: Nat Rev Microbiol Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Presumed asymptomatic carrier transmission of COVID-19 Concentration and detection of SARS coronavirus in sewage from Xiao Tang Shan Hospital and the 309th Hospital of the Chinese People's Liberation Army Stability of Middle East respiratory syndrome coronavirus (MERS-CoV) under different environmental conditions Washington State 2019-nCoV Case Investigation Team. Algorithm for the management of contacts of probable or confirmed COVID-19 cases Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Laboratory readiness and response for novel coronavirus (2019-nCoV) in expert laboratories in 30 EU/EEA countries Improved molecular diagnosis of COVID-19 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse transcription-polymerase chain reaction assay validated in vitro and with clinical specimens Coronavirus as a possible cause of severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease Structural insights into coronavirus entry Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2 Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Structure of SARS coronavirus spike receptor-binding domain complexed with receptor Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein The 2019-new coronavirus epidemic: evidence for virus evolution Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Structural basis of severe acute respiratory syndrome coronavirus ADP-ribose-1′′-phosphate dephosphorylation by a conserved domain of nsP3 COV-ID-2019: the role of the nsp2 and nsp3 in its pathogenesis The global spread of 2019-nCoV: a molecular evolutionary analysis.
    keywords: acid; bat; coronavirus; cov-2; covid-19; novel; position; residue; sars
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        item: #578 of 7819
          id: cord-252818-1gms4zw3
      author: Bouayed, Jaouad
       title: Behavioural manipulation ‐ key to the successful global spread of the new Coronavirus SARS‐Cov‐2?
        date: 2020-08-19
       words: 2492
      flesch: 39
     summary: In the following, we briefly emphasize the possibility of COVID-19 instigated behaviour, contributing to the rapid spread of the virus we observe. Regrettably, direct scientific evidence for behavioural changes from COVID-19 infected individuals are not (yet) available, and carefully controlled studies in this domain are warranted.
    keywords: behaviour; coronavirus; covid-19; sars; spread; transmission
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        item: #579 of 7819
          id: cord-252833-0lb60y12
      author: Rusch, Valerie W.
       title: The American College of Surgeons Responds to COVID-19
        date: 2020-07-14
       words: 2421
      flesch: 35
     summary: The infrastructure described in this document 21, 22 not only supported the ability to manage the surge of COVID-19 pandemic patients but also the healthcare system's response to future outbreaks and mass casualty events. In addition to NSQIP, other ACS registries are also adding COVID related variables.
    keywords: acs; cancer; care; covid-19; pandemic; patients; surgeons; trauma
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        item: #580 of 7819
          id: cord-252843-vd81pftu
      author: Doherty, Tanya
       title: Building back from the ground up: the vital role of communities
        date: 2020-10-07
       words: 2003
      flesch: 39
     summary: CHWs, community health workers. and school governing bodies to have the national school nutrition programme which provides a daily meal to roughly nine million children, reinstated 4 months after school closures. An important community cadre that has the potential to play a critical role in mitigation strategies in LMICs are community health workers (CHWs).
    keywords: chws; community; covid-19; health; response; services; south
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        item: #581 of 7819
          id: cord-252870-52fjx7s4
      author: Xie, Kefan
       title: The Impact of Risk Perception on Social Distancing during the COVID-19 Pandemic in China
        date: 2020-08-27
       words: 6277
      flesch: 39
     summary: Furthermore, safety climate positively predicts social distancing behaviors but lessens the positive correlation between risk perception and social distancing. The results show that risk perception significantly affects perceived understanding and social distancing behaviors in a positive way.
    keywords: behaviors; climate; covid-19; distancing; effect; pandemic; perception; public; risk; risk perception; safety; social; understanding
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        item: #582 of 7819
          id: cord-252903-pg0l92zb
      author: Abueg, M.
       title: Modeling the combined effect of digital exposure notification and non-pharmaceutical interventions on the COVID-19 epidemic in Washington state
        date: 2020-09-02
       words: 7328
      flesch: 36
     summary: In contrast, OpenABM-Covid19 ( 22 ) simulates concurrent manual contact tracing and digital exposure notification interventions over interaction networks at a large scale. key: cord-252903-pg0l92zb authors: Abueg, M.; Hinch, R.; Wu, N.; Liu, L.; Probert, W. J. M.; Wu, A.; Eastham, P.; Shafi, Y.; Rosencrantz, M.; Dikovsky, M.; Cheng, Z.; Nurtay, A.; Abeler-Do�rner, L.; Bonsall, D. G.; McConnell, M. V.; O'Banion, S.; Fraser, C. title: Modeling the combined effect of digital exposure notification and non-pharmaceutical interventions on the COVID-19 epidemic in Washington state date: 2020-09-02 journal: nan DOI: 10.1101/2020.08.29.20184135 sha: doc_id: 252903 cord_uid: pg0l92zb Contact tracing is increasingly being used to combat COVID-19, and digital implementations are now being deployed, many of them based on Apple and Google's Exposure Notification System.
    keywords: app; contact; covid-19; data; digital; epidemic; exposure; interventions; license; manual; model; notification; preprint
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        item: #583 of 7819
          id: cord-252914-51wvis1d
      author: Gaffney, Brian
       title: The impact of COVID-19 on clinical education of internal medicine trainees
        date: 2020-08-15
       words: 1199
      flesch: 33
     summary: Notably, there has been a change in the variety of presentations assessed by medical trainees through the formation of these parallel assessment pathways. This impacted significantly on the opportunities for medical trainees to learn at the bedside from senior supervising consultants and to have a forum of constructive feedback.
    keywords: covid-19; patients; trainees; training
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        item: #584 of 7819
          id: cord-252930-yfxst8bo
      author: Silingardi, Roberto
       title: Acute limb ischemia in COVID-19 patients: Could Aortic Floating Thrombus be the source of embolic complications?
        date: 2020-06-17
       words: 296
      flesch: 47
     summary: key: cord-252930-yfxst8bo authors: Silingardi, Roberto; Gennai, Stefano; Migliari, Mattia; Covic, Tea; Leone, Nicola title: Acute limb ischemia in COVID-19 patients: Could Aortic Floating Thrombus be the source of embolic complications? date: 2020-06-17 journal: J Vasc Surg DOI: 10.1016/j.jvs.2020.06.008 sha: doc_id: 252930 cord_uid: yfxst8bo nan Recently, Bellosta 1 demonstrated a significant higher incidence of acute limb ischemia (ALI) 4 in COVID-19 patients. The 6 increased thrombo-embolic complications in COVID-19 patients have been reported, even in 7 those receiving anticoagulant therapy and either in non-atherosclerotic.
    keywords: covid-19
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        item: #585 of 7819
          id: cord-252933-bu4oihem
      author: Xu, Jieqing Jessica
       title: Renal Infarct in a COVID‐19 Positive Kidney‐Pancreas Transplant Recipient
        date: 2020-06-01
       words: 1394
      flesch: 30
     summary: Throughout his hospitalization, he received high dose thromboembolism prophylaxis with enoxaparin 40 mg subcutaneously every 12 hours, as per institutional protocol which was modified to reflect the higher rate of thromboembolic events observed in COVID-19 patients. There is mounting evidence that COVID-19 patients are predisposed to both venous (5, 8, 9) and arterial (10) thromboembolic events.
    keywords: covid-19; disease; patients; transplant
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        item: #586 of 7819
          id: cord-252965-30pl5tx3
      author: Stutt, Richard O. J. H.
       title: A modelling framework to assess the likely effectiveness of facemasks in combination with ‘lock-down’ in managing the COVID-19 pandemic
        date: 2020-06-10
       words: 8017
      flesch: 41
     summary: We considered, therefore, the effects of varying the time of facemask adoption by the public and show that, even if facemask use began immediately while in the first lock-down period, major benefits would still be accrued by preventing the occurrence of further COVID-19 disease waves (figure 6a-c). This is clearly the worst case but we consider that, in practice, negative effects of facemask adoption are improbable, because countries where facemask use is mandatory have relatively low COVID-19 spread and numbers of deaths.
    keywords: adoption; covid-19; facemask; infection; inoculum; lock; model; population; public; sars; transmission; use; wearers
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        item: #587 of 7819
          id: cord-252991-gvlyn6j7
      author: Silva, V. O.
       title: PREVALENCE OF ANTIBODIES AGAINST SARS-CoV-2 IN PROFESSIONALS OF A PUBLIC HEALTH LABORATORY AT SAO PAULO, SP, BRAZIL
        date: 2020-10-21
       words: 4155
      flesch: 44
     summary: São Paulo is the most populous State and accordantly has the largest number of COVID-19 cases in the country, with 985.628 documented cases and 35.622 thousand deaths by the end of September 2020 (SEADE, 2020) . A large study in Denmark showed an overall seroprevalence of 3.4% (CI: 2.5%-3.8%) among health care workers.
    keywords: cov-2; covid-19; health; license; medrxiv; preprint; sars; workers
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        item: #588 of 7819
          id: cord-252998-8ynk9k8r
      author: Getaneh, Y.
       title: Global lessons and Potential strategies in combating COVID-19 pandemic in Ethiopia:Systematic Review
        date: 2020-05-26
       words: 3783
      flesch: 44
     summary: The alignment of public health measures to levels of transmission in a community is not fixed in stone. Unfortunately, in deferent countries, social distancing measures were not in place until it was too late; as a result, hospitals were filled to capacity, and a rapid transmission was observed, which had led to a steep spike in newer infections.
    keywords: cases; countries; covid-19; health; license; measures; preprint; review
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        item: #589 of 7819
          id: cord-253054-qipyqtsi
      author: Kokkoris, Michail D.
       title: Would You Sacrifice Your Privacy to Protect Public Health? Prosocial Responsibility in a Pandemic Paves the Way for Digital Surveillance
        date: 2020-09-18
       words: 4875
      flesch: 39
     summary: Could it be that prosocial responsibility, to which authorities appealed in order to enhance compliance with quarantine measures, also increases acceptance of digital surveillance and restrictions of privacy? We suggest that prosocial responsibility besides motivating people to comply with anti-pandemic measures also undermines people’s valuation of privacy.
    keywords: covid-19; measures; pandemic; privacy; responsibility; surveillance
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        item: #590 of 7819
          id: cord-253077-61fmul8c
      author: Vabret, Nicolas
       title: Immunology of COVID-19: current state of the science
        date: 2020-05-06
       words: 20264
      flesch: 30
     summary: Tan et al. proposed a prognostic model based on lymphocyte counts at two time points: patients with less than 20% lymphocytes at days 10-12 from the onset of symptoms and less than 5% at days 17-19 had the worst outcomes in this study (Tan et al., 2020a) . Antibodies binding the SARS-CoV-2 internal N protein and the external S glycoprotein are commonly detected (Amanat et al., 2020; Ju et al., 2020; .
    keywords: 2020b; antibodies; antibody; blood; cd4; cells; coronavirus; cov-2; covid-19; covid-19 patients; cytokine; disease; et al; hcq; human; ifn; immune; infection; inflammatory; levels; lung; mers; patients; potential; protein; respiratory; responses; sars; sars coronavirus; severity; specific; studies; study; syndrome; t cells; treatment; vaccine
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        item: #591 of 7819
          id: cord-253079-aohqinlo
      author: Cannizzaro, Renato
       title: Covid-19 and cancer patients: Choosing wisely is the key
        date: 2020-04-08
       words: 806
      flesch: 44
     summary: Intensive care units in hospitals committed to managing patients with severe symptoms of Covid-19 may not be able to provide care for cancer patients. SARS-CoV-2 transmission in patients with cancer at a tertiary care hospital in Wuhan, China Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Risk of COVID-19 for cancer patients Risk of COVID-19 for patients with cancer Managing COVID-19 in the oncology clinic and avoiding the distraction effect COVID-19 epidemic: proposed alternatives in the management of digestive cancers: A French Intergroup clinical point of view COVID-19) outbreak: what the department of endoscopy should know Implications of COVID-19 for patients with pre-existing digestive diseases
    keywords: cancer; covid-19; patients
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        item: #592 of 7819
          id: cord-253104-yggcf7q2
      author: Usul, Eren
       title: The role of hematological parameters in COVID-19 patients in the emergency room
        date: 2020-07-21
       words: 3583
      flesch: 44
     summary: In the results of this study, which are also consistent with previous research, low thrombocyte, leukocyte and neutrophil counts were revealed in COVID-19 positive patients. Also, hemoglobin levels in COVID-19 positive patients were found to be significantly higher than in COVID-19-negative patients.
    keywords: covid-19; lymphocyte; neutrophil; nlr; patients; study; test
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        item: #593 of 7819
          id: cord-253124-s3pa4n8a
      author: Dhamad, Ahmed E.
       title: COVID-19: molecular and serological detection methods
        date: 2020-10-07
       words: 3377
      flesch: 40
     summary: And the top keywords that searched were: COVID-19, SARS-CoV-2, coronavirus, genomic RNA, protein structure, ACE2, transmission, symptoms, molecular detection methods, serological detection methods, rRT-PCR, ID NOW COVID-19, isothermal amplification, CRISPR, SARS-CoV-2 DETECTR, LAMP, recombinase polymerase amplification (RPA), Lateral flow assay (LFA) and Enzyme-linked immunosorbent assay (ELISA). In this review, we summarized the current knowledge about COVID-19 detection methods aiming to highlight the advantages and disadvantages of molecular and serological methods.
    keywords: control; coronavirus; cov-2; covid-19; detection; igg; methods; sars
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        item: #594 of 7819
          id: cord-253162-lebgynsz
      author: Chang, Tsai-Yu
       title: Innovation of dental education during COVID-19 pandemic
        date: 2020-08-19
       words: 3767
      flesch: 52
     summary: Dental education during COVID-19 pandemic 5 + MODEL 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Transmission routes of 2019-nCoV and controls in dental practice Association of infected probability of COVID-19 with ventilation rates in confined spaces: a Wells-Riley equation based investigation Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travelers from Wuhan, China Persistence of coronaviruses on inanimate surfaces and its inactivation with biocidal agents Pathogenicity and transmissibility of 2019-nCoVda quick overview and comparison with other emerging viruses Impact of COVID-19 on dental education in the United States University of Sydney experts. The model of dental education should be innovated to suit different situations and novelty intelligent technology should be applied for future dental education.
    keywords: countries; covid-19; dental; education; online; pandemic; students; university
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        item: #595 of 7819
          id: cord-253170-mjy4culg
      author: Parra-Lara, Luis Gabriel
       title: Azithromycin and SARS-CoV-2 infection: where we are now and where we are going
        date: 2020-07-01
       words: 1332
      flesch: 40
     summary: Anti-inflammatory effects include modulating the production of pro-inflammatory cytokines such as IL-6, IL-1beta and acceleration of phagocytosis capacity of macrophages, classifying Azithromycin as a senolytic drug that selectively attacks and kills senescent cells, with an efficiency of almost 97% (1) (2) (3) . key: cord-253170-mjy4culg authors: Parra-Lara, Luis Gabriel; Martínez-Arboleda, Juan José; Rosso, Fernando title: Azithromycin and SARS-CoV-2 infection: where we are now and where we are going date: 2020-07-01 journal: J Glob Antimicrob Resist DOI: 10.1016/j.jgar.2020.06.016 sha: doc_id: 253170 cord_uid: mjy4culg • Due to its mechanism of action and various anti-inflammatory effects, azithromycin is a promising medicine for the treatment of the coronavirus COVID-19.
    keywords: azithromycin; covid-19; hydroxychloroquine
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        item: #596 of 7819
          id: cord-253196-et1ekgdl
      author: Yazdany, Jinoos
       title: Use of Hydroxychloroquine and Chloroquine During the COVID-19 Pandemic: What Every Clinician Should Know
        date: 2020-03-31
       words: 1331
      flesch: 38
     summary: Well-done, randomized clinical trials should be performed urgently to test potential therapies, including HCQ. The antimalarials hydroxychloroquine (HCQ) and chloroquine (CQ) have demonstrated antiviral activity against severe acute respiratory syndromecoronavirus 2 (SARS-CoV-2) in vitro and in small, poorly controlled or uncontrolled clinical studies (1) (2) (3) .
    keywords: covid-19; hcq; hydroxychloroquine; patients
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        item: #597 of 7819
          id: cord-253201-r6vsa0pw
      author: Nazari, S.
       title: Central Nervous System Manifestations in COVID-19 Patients: A Systematic Review and Meta-analysis
        date: 2020-07-22
       words: 3961
      flesch: 41
     summary: In this study, we aimed to evaluate the CNS presentations in COVID-19 patients in an attempt to identify the common CNS features and provide a better overview to tackle this new pandemic. However, a growing number of COVID-19 patients are presenting with different combinations of the central nervous system (CNS) manifestations [16]
    keywords: cns; coronavirus; covid-19; disease; infection; license; medrxiv; patients; preprint
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        item: #598 of 7819
          id: cord-253208-wknht58z
      author: Wang, Xue
       title: Ratios of neutrophil-to-lymphocyte and platelet-to-lymphocyte predict all-cause mortality in inpatients with coronavirus disease 2019 (COVID-19): a retrospective cohort study in a single medical centre
        date: 2020-09-09
       words: 3959
      flesch: 48
     summary: [26] , the NLR was significantly higher in severe patients, when compared to non-severe patients, at all time points after hospital admission, and the NLR was positively correlated with hospitalisation time from day 5 after admission. [4] reported that severe cases are likely to have higher NLRs caused by the higher neutrophil counts, but these cases would have lower lymphocyte counts, when compared to non-severe patients, indicating that the surveillance of NLRs might be helpful for the early screening of the critical illness of COVID-19.
    keywords: coronavirus; covid-19; disease; mortality; nlr; patients; study
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        item: #599 of 7819
          id: cord-253214-ypt2s8ek
      author: Choudhary, Bharat
       title: Management Concern for Non-COVID Children During the COVID-19 Pandemic
        date: 2020-05-04
       words: 406
      flesch: 47
     summary: [1] focusses on symptoms of COVID-19 infection and any epidemiological link (either foreign travel history, direct contact of COVID-19 patient, health worker or if patient coming from hot spot area) to maximize the sensitivity of the screening criteria. key: cord-253214-ypt2s8ek authors: Choudhary, Bharat; Goyal, Jagdish Prasad title: Management Concern for Non-COVID Children During the COVID-19 Pandemic date: 2020-05-04 journal: Indian Pediatr DOI: 10.1007/s13312-020-1874-y sha: doc_id: 253214 cord_uid: ypt2s8ek nan Indian Council of Medical Research (ICMR) has released guidelines for coronavirus disease (COVID-19) testing in India and has been updating it frequently.
    keywords: covid-19
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        item: #600 of 7819
          id: cord-253238-ptmxkpae
      author: Kopel, Jonathan
       title: Clinical Insights into the Gastrointestinal Manifestations of COVID-19
        date: 2020-05-23
       words: 4158
      flesch: 41
     summary: Given the high percentage of COVID-19 patients that present with GI symptoms (e.g., nausea and diarrhea), screening patients for GI symptoms remain essential. Given the high percentage of COVID-19 patients that present with GI symptoms (diarrhea, nausea, etc.), screening these patients is essential.
    keywords: cases; coronavirus; covid-19; disease; human; infection; patients; sars; symptoms; syndrome
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        item: #601 of 7819
          id: cord-253250-zet48zcl
      author: Thaden, J.T.
       title: When two for the price of one isn’t a bargain: Estimating prevalence and microbiology of bacterial co-infections in patients with COVID-19
        date: 2020-09-09
       words: 875
      flesch: 18
     summary: There was heterogeneity in the outcomes of the studies that were included in the meta-analysis, as some reported whether bacterial infection was noted on presentation to the hospital (n=20 studies; termed bacterial co-infection), while the remaining studies reported whether a concomitant bacterial infection developed during the course of the patient's hospitalization (n=8 studies; termed secondary bacterial infection). Interestingly, stratification of patients by illness severity showed that bacterial infections were more prevalent in fatal (11.6%) and ICU (8.1%) cases relative to non-ICU hospitalized patients (5.8%).
    keywords: bacterial; patients
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        item: #602 of 7819
          id: cord-253252-s8fm5rfa
      author: Jayaweera, Mahesh
       title: Transmission of COVID-19 virus by droplets and aerosols: A critical review on the unresolved dichotomy
        date: 2020-06-13
       words: 14122
      flesch: 36
     summary: With the onset of the COVID-19 pandemic, many researchers have been in the development of effective filtering mechanisms to combat SARS-CoV-2-laden aerosol transmission; however, until early May 2020, there have been no promising PPE developed to curtail such transmission. Morawska (2006) has presented a classification for virus transmission, including human-human transmission, airborne transmission, and other means of transmission such as endogenous infection, common vehicle, and vector spread.
    keywords: aerosols; air; cov-2; covid-19; disease; droplets; et al; humidity; infection; influenza; masks; particles; person; sars; temperature; transmission; virus
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        item: #603 of 7819
          id: cord-253256-909chgl0
      author: Bajwa, Sukhminder Jit Singh
       title: Peri-operative and critical care concerns in coronavirus pandemic
        date: 2020-03-28
       words: 4550
      flesch: 39
     summary: In this scenario, it is prudent to follow the national and international guidelines and treat any suspected patient as positive and to take necessary precautions during anaesthesia and critical care of such patients. For any emergency surgery in such patients, planning of anaesthesia becomes very crucial while taking all the necessary precautions.
    keywords: care; cases; coronavirus; covid-19; health; infection; isolation; novel; patients; pressure; procedure; risk; transmission; use
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        item: #604 of 7819
          id: cord-253264-vt2rei7e
      author: Hahad, Omar
       title: Bevölkerungsbezogene psychische Gesundheit als Schlüsselfaktor im Umgang mit COVID-19
        date: 2020-04-30
       words: 1162
      flesch: 29
     summary: Daher sind Maßnahmen notwendig, wie auch von der WHO und anderen Gesundheitsorganisationen empfohlen, die sich spezifisch mit den negativen Auswirkungen im Hinblick auf die psychische Gesundheit in der Bevölkerung befassen, insbesondere bei sensiblen Gruppen wie Frontarbeitern. Ein wichtiger Bestandteil solcher Maßnahmen sollte, unabhängig von der exakten Gestaltung, die Akzeptanz und Normalisierung von Ängsten und negativen Emotionen darstellen, da akuter psychischer Stress bei Konfrontation mit einem Ereignis solchen Ausmaßes eine normale Reaktion ist.
    keywords: covid-19; der; die; fear; health; mit; und; von
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        item: #605 of 7819
          id: cord-253285-kskuz1ug
      author: Hage, René
       title: 444Calcineurin Inhibitors and COVID-19
        date: 2020-09-24
       words: 191
      flesch: 28
     summary: The Brazilian Journal of Infectious Diseases COVID-19 in Patients with Solid Organ Transplantation: A Systematic Review Suppression of coronavirus replication by cyclophilin inhibitors Cyclosporin A inhibits the replication of diverse coronaviruses MERS CoV infection in two renal transplant recipients: Case report Replication of human coronaviruses SARS-CoV, HCoV-NL63 and HCoV-229E is inhibited by the drug FK506 Human coronavirus NL63 replication is cyclophilin A-dependent and inhibited by non-immunosuppressive cyclosporine A-derivatives including Alisporivir Clinical Trial to Evaluate Methylprednisolone Pulses and Tacrolimus in Patients With COVID-19 Lung Injury (TACROVID)
    keywords: covid-19
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        item: #606 of 7819
          id: cord-253312-bf35afpj
      author: Unal, Gokhan
       title: Immunopharmacological management of COVID-19: Potential therapeutic role of valproic acid
        date: 2020-05-27
       words: 1096
      flesch: 36
     summary: Regarding the given immunomodulatory effects of valproic acid, it has been suggested that the drug might provide benefits for ARDS due to the exaggerated immune response related to COVID-19. This study consolidates the findings showing the antiviral activity of valproic acid and gives hope for its potential usage in the COVID-19 pandemic.
    keywords: acid; covid-19; valproic
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        item: #607 of 7819
          id: cord-253343-3dmuxts5
      author: Zhang, Ruochi
       title: COVID19XrayNet: A Two-Step Transfer Learning Model for the COVID-19 Detecting Problem Based on a Limited Number of Chest X-Ray Images
        date: 2020-09-21
       words: 4083
      flesch: 52
     summary: This study employed multiple image augmentation techniques to generate simulated images of the training dataset of dsPneumonia, so that the deep neural network COV-ID19XrayNet could be trained with a sufficient number of chest X-ray images. Our experimental data also suggested that the proposed model may be further refined with more COVID-19 chest X-ray images.
    keywords: chest; covid-19; dataset; images; learning; model; ray; training
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        item: #608 of 7819
          id: cord-253345-r4dhmpq1
      author: Khan, Muhammad Bilal
       title: A Systematic Review of Non-Contact Sensing for Developing a Platform to Contain COVID-19
        date: 2020-09-30
       words: 8909
      flesch: 46
     summary: A Wi-Fi signal-based spatial diversity aware non-contact activity recognition system (Wi-SDAR) was introduced. Finally, we highlight challenges in developing non-contact sensing platforms to effectively control the COVID-19 situation.
    keywords: activities; activity; contact; covid-19; data; health; human; monitoring; non; platform; recognition; sensing; system; wcsi; wireless
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        item: #609 of 7819
          id: cord-253367-n6c07x9q
      author: Ussai, Silvia
       title: Hazard Prevention, Death and Dignity During COVID-19 Pandemic in Italy
        date: 2020-09-18
       words: 1850
      flesch: 48
     summary: Italy banned burial procedures based (i) on the recent acknowledgment about the virus environmental stability as well as (ii) its national civil contingency plan. Italy banned burial procedures based (i) on the recent acknowledgment about the virus environmental stability as well as (ii) its national civil contingency plan.
    keywords: burial; covid-19; families; italy
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        item: #610 of 7819
          id: cord-253392-cws6uj3c
      author: Wang, Yali
       title: The pros and cons of traditional Chinese medicines in the treatment of COVID-19
        date: 2020-05-03
       words: 863
      flesch: 36
     summary: Research Team E-BMCoCIE, Promotive Association for M, Health C. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version) Traditional Chinese medicine for COVID-19 treatment The use of Traditional Chinese Medicines to treat SARS-CoV-2 may cause more harm than good Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2) key: cord-253392-cws6uj3c authors: Wang, Yali; Zeng, Xian; Zhao, Yufen; Chen, Weiping; Chen, Yu Zong title: The pros and cons of traditional Chinese medicines in the treatment of COVID-19 date: 2020-05-03 journal:
    keywords: covid-19; medicines
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        item: #611 of 7819
          id: cord-253393-3y5bb8f0
      author: Clarke, Mattea
       title: Establishing prison-led contact tracing to prevent outbreaks of COVID-19 in prisons in Ireland
        date: 2020-06-22
       words: 2861
      flesch: 50
     summary: Contact tracing is an important contributor to the longer-term management strategy for COVID-19 in prisons as well as in the community but is highly resource-intensive. This paper describes the approach to contact tracing taken by the Irish Prison Service (IPS).
    keywords: case; contact; covid-19; ips; prison; sta
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        item: #612 of 7819
          id: cord-253410-rdmopd4t
      author: Gorzkowski, Victor
       title: Evolution of olfactory disorders in COVID‐19 patients
        date: 2020-07-02
       words: 2742
      flesch: 47
     summary: It has been suggested that SARS-CoV-2 causes obstructive inflammation of olfactory clefts 9 , or targets and damages olfactory epithelium support and stem cells leading to olfactory disturbances in COVID-19 patients 10 . Knowing the spontaneous evolution of olfactory disorders and its possibility of recovery in COVID-19 patients is very useful to inform and reassure patients.
    keywords: covid-19; loss; olfactory; patients; recovery; time
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        item: #613 of 7819
          id: cord-253431-fjds5cdr
      author: Erukainure, Ochuko L.
       title: Targeting the initiation and termination codons of SARS-CoV-2 spike protein as possible therapy against COVID-19: the role of novel harpagide 5-O-β-D-glucopyranoside from Clerodendrum volubile P Beauv. (Labiatae)
        date: 2020-11-03
       words: 6238
      flesch: 36
     summary: Druglikeness properties of compounds screen-out promising ligands that are likely to be used as drugs based on some identified properties (Dong et al., 2018) . Five hydrogen bond donors and ten hydrogen bond acceptors are required for a ligand to possess a satisfactory bioavailability and the optimum number of drug-target interactions via hydrogen bonds (Dong et al., 2018) .
    keywords: binding; cases; compound; coronavirus; cov-2; covid-19; disease; drug; erukainure; et al; glucopyranoside; protein; receptor; sars; spike; volubile
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        item: #614 of 7819
          id: cord-253456-u9num2o9
      author: Zhang, Che
       title: Clinical and epidemiological characteristics of pediatric SARS-CoV-2 infections in China: A multicenter case series
        date: 2020-06-16
       words: 4545
      flesch: 45
     summary: However, information on pediatric patients is limited. We describe the clinical and epidemiological characteristics of pediatric patients to provide valuable insight into the early diagnosis and assessment of COVID-19 in children.
    keywords: cases; clinical; covid-19; data; lesions; patients; sars
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        item: #615 of 7819
          id: cord-253552-qreg4emx
      author: Bouaziz, JD
       title: Vascular skin symptoms in COVID‐19: a french observational study
        date: 2020-04-27
       words: 762
      flesch: 34
     summary: Importantly, French dermatologists belonging to the SNDV reported numerous chilblain lesions in persons in close contact with COVID-19+ patients without COVID-19 PCR confirmation and without general symptoms of COVID-19 infections which raises 3 hypotheses: these chilblain lesions may: i/ be due to another confounding factor than COVID-19, ii/ be due to a post viral immunological reaction in asymptomatic forms of COVID-19, iii/ represent a skin presentation of COVID-19 infection in a subgroup of patients with peculiar immune anti-viral response. Usual clinical manifestations of COVID-19 infection include fever, fatigue, myalgia, headache, diarrhea, dry cough, dyspnea that may lead to acute respiratory distress syndrome and death (1).
    keywords: covid-19; patients; skin
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        item: #616 of 7819
          id: cord-253556-p1y0zeo1
      author: Rhodes, Scott D.
       title: A rapid qualitative assessment of the impact of the COVID-19 pandemic on a racially/ethnically diverse sample of gay, bisexual, and other men who have sex with men living with HIV in the US South
        date: 2020-08-12
       words: 5503
      flesch: 51
     summary: This commitment to prevention was noted by other participants. We collected qualitative data from participants who had completed 12 months of participation in and had graduated from the weCare intervention.
    keywords: african; american; covid-19; health; hiv; impact; living; men; pandemic; participants; plwh; white; years
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        item: #617 of 7819
          id: cord-253572-9qixiew8
      author: Bennett, David
       title: Portable pocket-sized ultrasound scanner for the evaluation of lung involvement in COVID-19 patients
        date: 2020-09-21
       words: 2273
      flesch: 35
     summary: COVID-19 lung ultrasound in emergency department Pathogenesis of COVID-19 from a cell biology perspective Lung Ultrasound for Critically Ill Patients Lung Ultrasound in COVID-19 Pneumonia: Lancet Point-of-care lung ultrasound in patients with COVID-19 -a narrative review Is There a Role for Lung Ultrasound During the COVID-19 Pandemic? Comparison of a pocket-size ultrasound device with a premium ultrasound machine: diagnostic value and time required in bedside ultrasound examination Clinical features and treatment of COVID-19 patients in northeast Chongqing Usefulness of lung ultrasound Blines in connective tissue disease-associated interstitial lung disease: a literature review Monitoring transmissibility and mortality of COVID-19 in Comparative study of lung ultrasound and chest computed tomography scan in the assessment of severity of confirmed COVID-19 pneumonia
    keywords: covid-19; lung; patients; ultrasound
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        item: #618 of 7819
          id: cord-253609-vi2fb43t
      author: Gopinathannair, Rakesh
       title: COVID-19 and cardiac arrhythmias: a global perspective on arrhythmia characteristics and management strategies
        date: 2020-06-03
       words: 3204
      flesch: 41
     summary: Large prospective studies to better define arrhythmic manifestations as well as the safety of treatment strategies in COVID-19 patients are warranted. A variety of supraventricular and ventricular arrhythmias were reported in COVID-19 patients.
    keywords: azm; covid-19; hcq; patients; respondents; survey; usa
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        item: #619 of 7819
          id: cord-253618-bosb7e63
      author: Ramteke, Shobhana
       title: Novel coronavirus disease 2019 (COVID-19) pandemic: considerations for the biomedical waste sector in India
        date: 2020-08-01
       words: 2739
      flesch: 49
     summary: During this epidemic condition, expulsion of biomedical waste created from crisis facilities treating COVID-19 patients in like manner demands unprecedented thought as they can be potential bearers of the disease SARS-CoV-2. All together for the infection to finish section into the cell following this underlying procedure, the spike protein must be Biomedical waste is a result of medicinal services rehearses that incorporates sharps, nonsharps, blood, body parts, synthetic substances, pharmaceuticals, clinical gadgets and radioactive materials.
    keywords: coronavirus; cov-2; covid-19; figure; india; novel; sars; waste
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        item: #620 of 7819
          id: cord-253638-5f9ofdsc
      author: Alsaied, Tarek
       title: Coronavirus Disease 2019 (COVID‐19) Pandemic Implications in Pediatric and Adult Congenital Heart Disease
        date: 2020-06-10
       words: 5693
      flesch: 42
     summary: Arrhythmia is also commonly seen in COVID-19 patients and while nonspecific, palpitations are one of the presenting symptoms in 7% of the patients 31, 44, 54 . There is no information to suggest any harmful effect in COVID-19 patients thus it is reasonable to continue these medications.
    keywords: article; cardiovascular; care; cases; copyright; coronavirus; covid-19; disease; heart; patients; rights; risk
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        item: #621 of 7819
          id: cord-253648-n13sgorb
      author: Zhang, C.
       title: The Role of Weather Conditions in COVID-19 Transmission: A Study of a Global Panel of 1236 Regions
        date: 2020-07-30
       words: 8108
      flesch: 46
     summary: 253648 cord_uid: n13sgorb Weather condition may impact COVID-19 transmission. The effects of temperature and humidity on COVID-19 transmission are not clear due to the difficulties in separating impacts of social distancing.
    keywords: covid-19; effect; government; humidity; july; license; medrxiv; medrxiv preprint; population; preprint; temperature; transmission; version
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        item: #622 of 7819
          id: cord-253665-1dn3ek34
      author: Vishnubalaji, Radhakrishnan
       title: Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response
        date: 2020-07-07
       words: 5434
      flesch: 32
     summary: IPA uses precise algorithms to predict functional regulatory networks from gene expression data and provides a significance score for each network according to the fit of the network to the set of focus genes in the database. Mapping and aligning RNA-seq data to the NCBI viral genome reference sequence revealed expression of orf1ab_8, S_14, M_51, ORF67a, ORF8_8 and N_65 viral genes (Figure 5b ).
    keywords: analysis; cells; cov-2; covid-19; data; expression; figure; genes; infection; interferon; lung; nhbe; response; sars
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        item: #623 of 7819
          id: cord-253693-xdmgvj4p
      author: Adekoya, Oluwasegun B.
       title: How COVID-19 drives connectedness among commodity and financial markets: Evidence from TVP-VAR and causality-in-quantiles techniques
        date: 2020-10-20
       words: 10018
      flesch: 50
     summary: However, the studies are largely in parts, with the important role of oil market in influencing other markets appearing to dominate. For instance, Gajardo et al. (2018) employ the MF-ADCCS to analyze the existence of cross-correlation among gold price, oil market, bitcoin, exchange rates and the DJIA.
    keywords: assets; causality; connectedness; covid-19; et al; financial; gold; markets; net; oil; pandemic; price; spillover; stock; stock markets; volatility
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        item: #624 of 7819
          id: cord-253704-y0t30xw3
      author: Lahiri, Durjoy
       title: COVID-19 Pandemic: A Neurological Perspective
        date: 2020-04-29
       words: 4350
      flesch: 36
     summary: The most vital clinical information which we gather is that impaired consciousness may be a presenting feature of COVID-19, and therefore, a high index of suspicion for such patients will be the key to prevent or, at least, lessen exposure to health care providers and other patients. Another very recent report describes the occurrence of acute hemorrhagic necrotizing encephalopathy in COVID-19 patient [15] .
    keywords: acute; cases; coronavirus; covid-19; features; infection; involvement; patients; sars
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        item: #625 of 7819
          id: cord-253714-v02fs28k
      author: Bukhari, Syed Usama Khalid
       title: The diagnostic evaluation of Convolutional Neural Network (CNN) for the assessment of chest X-ray of patients infected with COVID-19
        date: 2020-03-31
       words: 2411
      flesch: 46
     summary: The third group contains digital images of chest X-rays of patients diagnosed with COVID-19 infection while the second group contains images of lung with pneumonia caused by other pathogens. In this regard, one of the important areas is the interpretation of radiological images with the help of artificial intelligence.
    keywords: chest; covid-19; images; pneumonia; rays
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        item: #626 of 7819
          id: cord-253730-cdkzvfib
      author: Suzuki, Emily
       title: Assessment of the Need for Early Initiation of Rehabilitation Treatments in Patients with Coronavirus Disease 2019
        date: 2020-08-13
       words: 3458
      flesch: 41
     summary: Resources for rehabilitation of patients with COVID-19 are limited, and no report has described the rehabilitation of moderate to severe COVID-19 patients in the acute phase. Physiotherapy management for COVID-19 in the acute hospital setting: clinical practice recommendations Covid-19 and post intensive care syndrome: a call for action COVID-19-related severe hypercoagulability in patients admitted to intensive care unit for acute respiratory failure Hypercoagulability of COVID-19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome Clinical observation and management of COVID-19 patients British Thoracic Society Standards of Care Committee Pulmonary Embolism Guideline Development Group: British Thoracic Society guidelines for the management of suspected acute pulmonary embolism Investigation of the freely available easyto-use software 'EZR' for medical statistics Risk factors of critical & mortal COVID-19 cases: a systematic literature review and meta-analysis Letter to the Editor: Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease Watching television and risk of mortality from pulmonary embolism among Japanese men and women Physical inactivity and idiopathic pulmonary embolism in women: prospective study Clinical features of patients infected with 2019 novel coronavirus in China Medical Treatment Expert Group for Covid-19:
    keywords: covid-19; hospital; patients; rehabilitation; risk; ventilation
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        item: #627 of 7819
          id: cord-253735-0wi67tuw
      author: Niu, Shengmei
       title: Clinical characteristics of older patients infected with COVID-19: A descriptive study
        date: 2020-04-10
       words: 2929
      flesch: 46
     summary: key: cord-253735-0wi67tuw authors: Niu, Shengmei; Tian, Sijia; Lou, Jing; Kang, Xuqin; Zhang, Luxi; Lian, Huixin; Zhang, Jinjun title: Clinical characteristics of older patients infected with COVID-19: This study focused on older patients with COVID-19 infection and analyzed the epidemiological and clinical characteristics of them.
    keywords: covid-19; infection; patients; study; years
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        item: #628 of 7819
          id: cord-253736-cd4qnp2m
      author: Modenese, Alberto
       title: Increased Risk of COVID-19-Related Deaths among General Practitioners in Italy
        date: 2020-06-03
       words: 2359
      flesch: 38
     summary: After this exclusion, the number of physician deaths due to COVID-19 which occurred in Italy by the 30 April 2020 is reduced to 118. Other important points to be stressed are the progressive activation, since the second half of March, in many Italian regions, of special medical units for the assistance of COVID-19 patients at home, called USCA (Unità Speciali di Continuità Assistenziale), as prescribed by a national decree [20] , and the promotion of telemedicine procedures, when possible [21] .
    keywords: covid-19; gps; italian; italy; patients; physicians
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        item: #629 of 7819
          id: cord-253746-15w4gquq
      author: Goldman, Michel
       title: Reflections on the Collaborative Fight Against COVID-19
        date: 2020-09-17
       words: 1633
      flesch: 33
     summary: It is therefore important that patient organizations are involved early on in the design of clinical trials. Finally, as discussed in the next section, patients should now be invited to take an active role in the design of COVID-19 trials.
    keywords: covid-19; interventions; patients; trials
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        item: #630 of 7819
          id: cord-253777-h8wy0coq
      author: Afshar, Hale
       title: Evolution and resolution of brain involvement associated with SARS- CoV2 infection: A close Clinical – Paraclinical follow up study of a case
        date: 2020-05-21
       words: 1566
      flesch: 39
     summary: The use of IVIg in severe COVID-19 patients may prevent or ameliorate CNS involvement, as seem to happen for our patient compared to ANE case. Chest CT showed multiple peripheral patchy ground-glass opacities with typical covid-19 distribution (day 10); these opacities later formed bilateral peripheral consolidation (day 22) (figure 1).
    keywords: cases; covid-19; day; encephalitis; patient
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        item: #631 of 7819
          id: cord-253800-cdyiwru9
      author: Eshraghi, Adrien A.
       title: Potential Mechanisms for COVID-19 Induced Anosmia and Dysgeusia
        date: 2020-09-16
       words: 2504
      flesch: 37
     summary: Since high levels of TNF-α, IFNγ, and IL-6 have been observed in serum of laboratory-confirmed cases of COVID-19 patients, it is reasonable to speculate that these pro-inflammatory cytokines may lead to dysgeusia . Thus, objective measurements of dysgeusia in COVID-19 patients are urgently needed to validate and quantify this association.
    keywords: angiotensin; anosmia; covid-19; dysgeusia; taste
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        item: #632 of 7819
          id: cord-253833-0lajhqn5
      author: Misra-Hebert, Anita D
       title: Impact of the COVID-19 pandemic on healthcare workers risk of infection and outcomes in a large, integrated health system.
        date: 2020-08-19
       words: 2866
      flesch: 40
     summary: However, the overlap propensity score weighted proportions were 8.9 vs. 7.7 for HCW vs. non-HCW having a positive test with weighted odds ratio (OR) 1.17, 95% confidence interval (CI) 0.99-1.38. Among those testing positive, weighted proportions for hospitalization were 7.4 vs.15.9 for HCW vs. non-HCW with OR of 0.42 (CI 0.26-0.66) and for ICU admission: 2.2 vs.4.5 for HCW vs. non-HCW with OR of 0.48 (CI 0.20 -1.04).
    keywords: cov-2; covid-19; hcw; health; non; risk; sars; test
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        item: #633 of 7819
          id: cord-253853-jocwiafy
      author: Ahmed, Naseer
       title: Knowledge, Awareness and Practice of Health care Professionals amid SARS-CoV-2, Corona Virus Disease Outbreak
        date: 2020-05-17
       words: 3438
      flesch: 44
     summary: Summary of a Report of 72 314 Cases from the Chinese Center for Disease Control and Prevention Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing Presumed Asymptomatic Carrier Transmission of COVID-19 Clinical characteristics of coronavirus disease 2019 in China Dentists' awareness, perception, and attitude regarding COVID-19 and infection control: A cross-sectional study among Jordanian dentists Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19 High proportion of health care workers with COVID-19 in Italy is a stark warning to the world: protecting nurses and their colleagues must be the number one priority Protecting health-care workers from subclinical coronavirus infection COVID-19: protecting health-care workers Knowledge levels and attitudes of health care professionals toward patients with hepatitis C infection Archives of Clinical Infectious Diseases | Assessment of Iranian Nurses' Knowledge and Anxiety Toward COVID-19 During the Current Outbreak in Iran Knowledge and attitude of dentists toward implant retained restorations in Saudi Arabia Trends in complete denture impressions in Pakistan Guidelines for infection control in dental health-care settings--2003 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study The Novel Chinese Coronavirus (2019-nCoV) Infections: challenges for fighting the storm Knowledge and attitudes of medical staff in Chinese psychiatric hospitals regarding COVID-19. A cross sectional study was conducted by administering a well-structured questionnaire comprising of three sections including knowledge, attitude and practice amongst health care professionals in various hospitals and clinics, over a duration of two months ‘Feb-March’ 2020.
    keywords: awareness; care; covid-19; hcps; health; knowledge; professionals; study
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        item: #634 of 7819
          id: cord-253862-jl1zhg13
      author: Khalaf, Khalil
       title: SARS-CoV-2: Pathogenesis, and Advancements in Diagnostics and Treatment
        date: 2020-10-06
       words: 14633
      flesch: 37
     summary: A cohort study Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study Use of convalescent plasma therapy in SARS patients in Hong Kong Treatment with convalescent plasma for influenza A (H5N1) infection Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience Effectiveness of convalescent plasma therapy in severe COVID-19 patients Treatment of 5 critically Ill patients with COVID-19 with convalescent plasma Safety update: COVID-19 convalescent plasma in 20,000 hospitalized patients Severe acute respiratory syndrome coronavirus viroporin 3A activates the NLRP3 inflammasome The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China Biology of IL-38 and its role in disease IL-37 is a fundamental inhibitor of innate immunity Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by COVID-19 (CoV-19 or SARS-CoV-2): anti-inflammatory strategies Baricitinib as potential treatment for 2019-nCoV acute respiratory disease Use of baricitinib in patients with moderate and severe COVID-19 Evaluation of human monoclonal antibody 80R for immunoprophylaxis of severe acute respiratory syndrome by an animal study, epitope mapping, and analysis of spike variants Human monoclonal antibody as prophylaxis for SARS coronavirus infection in ferrets Human monoclonal antibody combination against SARS coronavirus: synergy and coverage of escape mutants Neutralizing epitopes of the SARS-CoV S-protein cluster independent of repertoire, antigen structure or mAb technology Monoclonal antibodies targeting the HR2 domain and the region immediately upstream of the HR2 of the S protein neutralize in vitro infection of severe acute respiratory syndrome coronavirus Neutralizing human monoclonal antibodies to severe acute respiratory syndrome coronavirus: target, mechanism of action, therapeutic potential Perspectives on monoclonal antibody therapy as potential therapeutic intervention for Coronavirus disease-19 (COVID-19) Similar to SARS, infected patients presented with a variety of clinical courses, from mild upper respiratory symptoms to fulminant pneumonia and multi-organ system failure.
    keywords: acute; antibodies; antibody; antiviral; cells; coronavirus; cov-2; covid-19; disease; et al; group; host; human; infection; novel; patients; protein; receptor; respiratory; rna; sars; study; syndrome; treatment; trial; use
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        item: #635 of 7819
          id: cord-253898-ajo60spn
      author: Chirico, Francesco
       title: “Questionable” peer review in the publishing pandemic during the time of COVID-19: implications for policy makers and stakeholders
        date: 2020-06-17
       words: 644
      flesch: 33
     summary: Second, peer review quality may be compromised by rushing the process and assigning excessive workload to peer reviewers, thus putting them under pressure and psychological stress. Moreover, a group of publishers and scholarly communication organizations created a reviewer pool, supported by the Open Access Scholarly Publishers Association to maximize the efficiency of peer review, ensuring that key work related to COVID-19 is reviewed and published as quickly and openly as possible (4).
    keywords: covid-19; peer
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        item: #636 of 7819
          id: cord-253908-zgk5d4c1
      author: Schrack, Jennifer A
       title: After the COVID-19 Pandemic: The Next Wave of Health Challenges for Older Adults
        date: 2020-04-21
       words: 1006
      flesch: 44
     summary: Even though outdoor activities have been permitted and even promoted for physical exercise, those in more crowded urban areas, and those at greater health risk, may be reluctant to leave their homes for fear of contracting the virus. 2. Increases in stress levels due to perceived health risk, financial concerns, and uncertainty about the future could trigger alterations in sleep/wake cycles, prolonged low-grade inflammation, increased depressive symptoms, and greater fatigue burden (3) (4) (5) .
    keywords: covid-19; health
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        item: #637 of 7819
          id: cord-253910-pmurx4jh
      author: Miles, David
       title: “Stay at Home, Protect the National Health Service, Save Lives”: a cost benefit analysis of the lockdown in the United Kingdom
        date: 2020-08-13
       words: 6376
      flesch: 55
     summary: The lowest estimate for lockdown costs incurred was 40% higher than highest benefits from avoiding the worst mortality case scenario at full life expectancy tariff and in more realistic estimations they were over 5 times higher. We consider the following scenarios for the consequences of each policy for the evolution of COVID-19 deaths: 1.
    keywords: article; copyright; covid-19; deaths; health; life; lockdown; restrictions; years
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        item: #638 of 7819
          id: cord-253918-8g3erth8
      author: Ienca, Marcello
       title: On the responsible use of digital data to tackle the COVID-19 pandemic
        date: 2020-03-27
       words: 1422
      flesch: 46
     summary: On the responsible use of digital data to tackle the COVID-19 pandemic date: 2020-03-27 journal: Nat Med DOI: 10.1038/s41591-020-0832-5 sha: doc_id: 253918 cord_uid: 8g3erth8 Large-scale collection of data could help curb the COVID-19 pandemic, but it should not neglect privacy and public trust. Transparent public communication about data processing for the common good should be pursued.
    keywords: covid-19; data; health; public
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        item: #639 of 7819
          id: cord-253933-29tedkf8
      author: David, Abel P.
       title: Tracheostomy guidelines developed at a large academic medical center during the COVID‐19 pandemic
        date: 2020-04-27
       words: 3039
      flesch: 38
     summary: Performing surgical tracheostomy and tracheostomy care requires a strategy that mitigates these risks and maintains the quality of patient care. Modified guidelines for all phases of tracheostomy care at an academic tertiary care center in the setting of COVID‐19 are presented.
    keywords: care; covid-19; pandemic; patients; ppe; risk; tracheostomy
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        item: #640 of 7819
          id: cord-253948-yi57n8nc
      author: Singh, K.
       title: Impact of weather indicators on the COVID-19 outbreak: A multi-state study in India
        date: 2020-06-16
       words: 1853
      flesch: 45
     summary: This study has shown evidence of weather indicators correlation with COVID-19 cases; however, there are various limitations under which this study has been conducted. [15] tests are considered in this study to investigate the correlation between weather indicators and COVID-19 cases.
    keywords: cases; covid-19; preprint; weather
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        item: #641 of 7819
          id: cord-253958-8lhzgqfr
      author: Clark, T. W.
       title: Diagnostic accuracy of a host response point-of-care test for identifying COVID-19
        date: 2020-06-02
       words: 4068
      flesch: 57
     summary: In addition, COVID-19 positive patients had higher CRP levels, lower white cell counts and were more likely to have radiological evidence of pneumonia, shown in Table 1 . In addition, lack of single occupancy rooms means that COVID-19 negative patients cohorted in these assessment areas may acquire infection from positive patients before test results are available.
    keywords: covid-19; febridx; license; medrxiv; perpetuity; preprint
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        item: #642 of 7819
          id: cord-253962-ug7yflxh
      author: Huang, Dong
       title: A novel risk score to predict diagnosis with Coronavirus Disease 2019 (COVID‐19) in suspected patients: A retrospective, multi‐center, observational study
        date: 2020-06-08
       words: 2463
      flesch: 53
     summary: 4 Respiratory failure, immunosuppression, as well as systemic infection and inflammation are already recognized as main clinical characteristics of COVID-19 patients. However, given the incidence of RT-PCR false-negative results, shortage of PCR kit, and possible delayed diagnosis due to timeconsuming process of RT-PCR, 6 an early efficient identification of confirmed COVID-19 patients is important for early diagnosis and treatments.
    keywords: covid-19; diagnosis; patients; risk; score; study
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        item: #643 of 7819
          id: cord-253968-jtr0p930
      author: López, Verónica
       title: Recomendaciones en el manejo de la pandemia por coronavirus SARS-CoV-2 (Covid-19) en pacientes con trasplante renal
        date: 2020-04-03
       words: 3628
      flesch: 42
     summary: El grado y la duración de la viremia y la viabilidad del virus dentro de la sangre o compartimentos de órganos específicos también afectarían al riesgo de transmisión de los donantes. Este manuscrito presenta una propuesta de actuación con recomendaciones generales y específicas para proteger y prevenir de la infección a esta población tan vulnerable como son los receptores de un trasplante renal.
    keywords: cada; casos; como; con; coronavirus; covid-19; del; dosis; día; días; infección; las; los; pacientes; para; población; por; que; renal; riesgo; sars; trasplante; tratamiento; una
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        item: #644 of 7819
          id: cord-253970-sbj869yy
      author: Agarwal, Amit
       title: Neurological emergencies associated with COVID-19: stroke and beyond
        date: 2020-08-11
       words: 2423
      flesch: 35
     summary: COVID-19 neurologic complication with CNS vasculitis-like pattern Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in The emerging threat of (micro)thrombosis in COVID-19 and its therapeutic implications Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Hypercoagulability in COVID-19: identification of arterial and venous thromboembolism in the abdomen, pelvis, and lower extremities The immunology of COVID-19: is immune modulation an option for treatment? Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 To our knowledge, this was the first study to systematically characterize neurological symptoms and neuroimaging findings in COVID-19 patients.
    keywords: complications; covid-19; manifestations; patients; stroke; syndrome
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        item: #645 of 7819
          id: cord-253990-m75xwrz9
      author: Wang, Zhiguo
       title: Covid‐19: From structure to therapeutic targeting in studying approved drugs and local DNA vaccination
        date: 2020-10-29
       words: 1127
      flesch: 34
     summary: 1 Similar to the SARS virus and dissimilar to the seasonal influenza virus, SARS-CoV-2 causes the high rates of mortality in COVID-19 patients without evident immunodeficiency, and sequelae of survivors, instigating panic in the general population. 3, 4 The authors have found a significantly reduced risk of mortality in COVID-19 patients having statin therapy, with the risk for 28-day all-cause mortality being 5.2% in the matched statin group and 9.4% in the matched non-statin group (P = .001) 3
    keywords: coronavirus; cov-2; covid-19; sars
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        item: #646 of 7819
          id: cord-253993-ynrthadj
      author: Belhassan, Assia
       title: Assessment of effective imidazole derivatives against SARS-CoV-2 main protease through computational approach
        date: 2020-09-18
       words: 1779
      flesch: 39
     summary: The possible mechanisms of action of 4-aminoquinolines (chloroquine/hydroxychloroquine) against Sars-Cov-2 infection (COVID-19): A role for iron homeostasis? Aminoquinolines against coronavirus disease 2019 (COVID-19): chloroquine or hydroxychloroquine The Diagnostic Utility of Multifocal Electroretinography in Detecting Chloroquine and Hydroxychloroquine Retinal Toxicity Diagnostic pitfalls and laboratory test interference after hydroxychloroquine intoxication: A case report Insights from nanomedicine into chloroquine efficacy against COVID-19 Inhibitory activity of hydroxychloroquine on COVID-19 main protease: An insight from MD-simulation studies Recommendations on screening for chloroquine and hydroxychloroquine retinopathy Contemporary Progress in the Synthetic Strategies of Imidazole and its Biological Activities Comparison of Hospitalized Patients with Acute Respiratory Distress Syndrome Caused by COVID-19 and H1N1 Design, synthesis and antiplasmodial activity of novel imidazole derivatives based on 7-chloro-4-aminoquinoline Structural and molecular modeling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Validation of the general purpose Tripos 5.2 force field A brief review and table of semiempirical parameters used in the Hueckel molecular orbital method Protein Data Bank PDB AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading Repurposing of known anti-virals as potential inhibitors for SARS-CoV-2 main protease using molecular docking analysis Moroccan Medicinal plants as inhibitors of COVID-19: Computational investigations Structure of M pro from SARS-CoV-2 and discovery of its inhibitors The authors declare that they have no competing interests. Among the drugs proposed to test the antiviral effect of COVID-19, we selected imidazole derivatives
    keywords: chloroquine; cov-2; hydroxychloroquine; protease; sars
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        item: #647 of 7819
          id: cord-253998-1jegybs9
      author: Lara, Pedro C
       title: Whole-lung Low Dose Irradiation for SARS-Cov2 Induced Pneumonia in the Geriatric Population: An Old Effective Treatment for a New Disease? Recommendation of the International Geriatric Radiotherapy Group
        date: 2020-05-09
       words: 2774
      flesch: 31
     summary: Hyper-elevation of Interleukin1 (IL-1), Tumor necrosis factor-1alfa (TNF-1 alfa), and Interleukin 6 (IL-6) produced by inflammatory macrophage M1 may damage the lung alveoli leading to severe pneumonitis, decreased oxygenation, and potential death despite artificial ventilation. It is postulated that the intense inflammation observed in the lung parenchyma (ARDS) is due to an inflammatory cascade characterized by elevation of Interleukin1 (IL-1), tumor necrosis factor 1 (TNF-1alfa) and interleukin 6 (IL-6) produced by inflammatory macrophage M1 [4] .
    keywords: dose; ldrt; lung; macrophage; patients; pneumonia; radiotherapy; treatment
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        item: #648 of 7819
          id: cord-254014-jowjkd12
      author: Rivillas, J. C.
       title: Social response to early-stage government control measures of COVID-19 in Colombia: population survey, April 8-20 2020.
        date: 2020-06-22
       words: 5949
      flesch: 57
     summary: https://doi.org/10.1101/2020.06.18.20135145 doi: medRxiv preprint In most cases -63% and 68% -all three groups supported physical distancing measures. • 79% of those showing symptoms voluntarily isolated themselves and complied with government isolation measures.
    keywords: covid-19; license; measures; medrxiv; people; preprint; years
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        item: #649 of 7819
          id: cord-254025-j1l0mder
      author: de Melo, Andreia C.
       title: Cancer inpatients with COVID-19: A report from the Brazilian National Cancer Institute
        date: 2020-10-26
       words: 3385
      flesch: 46
     summary: Therefore, the overall COVID-19-related mortality rate reached almost one third of the cases (60 [33.1%]), which was higher than that reported by other series with cancer patients [7, 8, 10, 12, 14] , and far exceeding the mortality reported for non-cancer patients [5] . There was no paired sample with non-cancer patients with COVID-19 or cancer patients without COVID-19 to provide a better comparison between the outcomes of morbidity and mortality.
    keywords: cancer; cases; covid-19; death; mortality; patients; study
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        item: #650 of 7819
          id: cord-254027-rndu5ake
      author: Geldsetzer, Pascal
       title: Using rapid online surveys to assess perceptions during infectious disease outbreaks: a cross-sectional survey on Covid-19 among the general public in the United States and United Kingdom
        date: 2020-03-17
       words: 4722
      flesch: 51
     summary: When asked what percent of individuals infected with Covid-19 experience a fatal disease course, the median estimate given by participants was 5.0% (IQR: 2.0% -15.0%) among US participants and 3.0% (IQR: 2.0% -10.0%) among UK participants. 67.5% (2,015/2,986) of US participants had a total household income between $20,000 and $99,999, and 74.4% (2,223/2,988) of UK participants had a total household income between GBP15,000 and GBP74,999.
    keywords: covid-19; license; medrxiv; participants; perpetuity; preprint
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        item: #651 of 7819
          id: cord-254043-1slz1dvr
      author: Jamil, Tahira
       title: No Evidence for Temperature-Dependence of the COVID-19 Epidemic
        date: 2020-08-26
       words: 2332
      flesch: 37
     summary: Analysis based on studies in China reported contrasting relationship between spread rate and temperature, ranging from positive relationship reported for Wuhan, China (6), for Chinese cities with very low (< 3 • C) ambient temperatures (7) , or positive (8) or negative (9) relationships for provinces across China, and lack of relationship between spread rates and temperature across cities in China (10) . Hence, our findings at the global scale, and consolidated across multiple time periods following the pandemic state, reject the hypothesis of a relationship between COVID-19 spread rates and ambient temperature, consistent with those of recent studies that also reported no evidence for an association of epidemic growth with temperature using different approaches and data (12) .
    keywords: covid-19; data; number; spread; temperature
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        item: #652 of 7819
          id: cord-254083-ea94wn3f
      author: Fowler, Alexander J.
       title: COVID-19 Phenotypes and Potential Harm of Conventional Treatments: How to Prove the Hypothesis
        date: 2020-08-15
       words: 1733
      flesch: 34
     summary: Importantly, the authors suggest that recommended treatment strategies for severe COVID-19 pneumonia based on ARDS management (3) may lead to disease progression and excess harm (1, 2) . For reference, patients enrolled in the PROSEVA (Prone Positioning in Severe ARDS) trial had a mean respiratory system compliance of 35 ml/cm H 2 O (SD, 15) at the time of enrollment (3).
    keywords: ards; authors; compliance; covid-19; patients
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        item: #653 of 7819
          id: cord-254094-ed1epul1
      author: Mayoral, Eduardo Pérez-Campos
       title: Factors related to asymptomatic or severe COVID-19 infection
        date: 2020-09-24
       words: 1670
      flesch: 37
     summary: A higher 2D:4D ratio is associated with COVID-19 severity in men [14] , this means that sex hormones play a role in protection, thus, causing women to develop less serious complications or an asymptomatic COVID-19 Infection and NS8 are likely to be phylogenetically associated with evolution of 2019-nCoV Amino acid catabolism: a pivotal regulator of innate and adaptive immunity Nutritional modulation of age-related changes in the immune system and risk of infection COVID-19 and the creation of a new disease The Emerging Threat of (Micro)Thrombosis in COVID-19 and Its Therapeutic Implications Extrapulmonary manifestations of COVID-19: Radiologic and clinical overview Immune-epidemiological parameters of the novel coronavirus -a perspective SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes Microthrombosis Associated with Gastrointestinal Bleeding in COVID-19 Neurological associations of COVID-19 Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases Ocular manifestations and clinical characteristics of 535 cases of COVID-19 in Wuhan, China: a cross-sectional study ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy Relationship between ABO blood group distribution and clinical characteristics in patients with COVID-19 25-Hydroxyvitamin D Concentrations Are Lower in Patients with Positive PCR for SARS-CoV-2 The authors thank Charlotte Grundy and Eli Cruz Parada for their assistance.
    keywords: asymptomatic; blood; covid-19; group; sars
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        item: #654 of 7819
          id: cord-254095-qkkimenx
      author: Garcés, Leah
       title: COVID-19 exposes animal agriculture’s vulnerability
        date: 2020-05-14
       words: 1021
      flesch: 61
     summary: Demand for animal meat grows about 2% each year, but sales of plant-based meat and other direct replacements for animal products jumped 11% in 2019 (Gaan 2020) . Several of the largest meat companies already offer plant-based protein as well as blended protein (part animal meat, part plant).
    keywords: animal; meat; plant; protein
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        item: #655 of 7819
          id: cord-254119-w6otllf5
      author: Ingraham, Nicholas E
       title: Immunomodulation in COVID-19
        date: 2020-05-04
       words: 1405
      flesch: 21
     summary: All remaining authors declare no competing interests. Division of Rheumatology (SL-E), Division of Infectious Disease and International Medicine (BKT), and Division of Hematology, Oncology and Transplantation (SGH), Department of Medicine (KT); Division of Pediatrics Infectious Disease and Immunology, Department of Pediatrics (BKT); Institute for Health Informatics School of Public Health (RAD); and Division of Acute Care Surgery ); and Veterans Affairs Medical Center Fact versus science fiction Antihypertensive drugs and risk of COVID-19? Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical and immunologic features in severe and moderate coronavirus disease 2019 Effective treatment of severe COVID-19 patients with tocilizumab COVID-19 illness in native and immunosuppressed states: a clinical-therapeutic staging proposal Anakinra in the treatment of polyarticularcourse juvenile rheumatoid arthritis: safety and preliminary efficacy results of a randomized multicenter study Interleukin-1 receptor blockade is associated with reduced mortality in sepsis patients with features of macrophage activation syndrome: reanalysis of a prior phase III trial A systematic review and metaanalysis of infection risk with small molecule JAK inhibitors in rheumatoid arthritis Ruxolitinib for the treatment of steroid-refractory acute GVHD (REACH1): a multicenter, open-label, phase 2 trial Ruxolitinib in adult patients with secondary haemophagocytic lymphohistiocytosis: an open-label, singlecentre, pilot trial Interferon independent non-canonical STAT activation and virus induced inflammation Anticytokine, JAK inhibitors, and antihypertensives can limit hyperinflammation by interacting and inhibiting these signalling cascades.
    keywords: clinical; covid-19; inhibitors; jak; patients
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        item: #656 of 7819
          id: cord-254121-soiloa5l
      author: Jani, Bhautesh Dinesh
       title: Recording COVID-19 consultations: review of symptoms, risk factors, and proposed SNOMED CT terms
        date: 2020-08-26
       words: 4052
      flesch: 37
     summary: 76, 77 Implications for research and practice The list of clinical terms can lead to the development of COVID-19 consultation templates, which in turn will help with standardised data collection and high quality research. 11 Table 1 Symptoms and assessment items relevant for COVID-19 primary care consultation with respective SNOMED CT concept identifiers Symptoms (with respective SNOMED CT concept identifiers) Primary care assessment (with respective SNOMED CT concept identifiers) Conceptualising implementation of consultation template GP consultation templates are often viewed as less patient-centred and potentially disruptive to communication.
    keywords: care; clinical; covid-19; items; meta; primary; review; snomed; systematic
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        item: #657 of 7819
          id: cord-254124-4p1ah2h3
      author: Khan, Asif Iqbal
       title: CoroNet: A Deep Neural Network for Detection and Diagnosis of COVID-19 from Chest X-ray Images
        date: 2020-06-05
       words: 2593
      flesch: 49
     summary: COVID-19 X-ray images are available at an open source Github repository by Joseph et al In this study, we propose CoroNet, a Deep Convolutional Neural Network model to automatically detect COVID-19 infection from chest X-ray images.
    keywords: chest; covid-19; images; learning; pneumonia; ray
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        item: #658 of 7819
          id: cord-254144-8h6cli5d
      author: Wallis, Lee A.
       title: African Federation for Emergency Medicine resources for managing COVID-19 in low resourced settings
        date: 2020-06-16
       words: 380
      flesch: 49
     summary: In the meantime, AFEM would like to signpost to the open access, interim WHO Clinical management of COVID-19 guidelines. key: cord-254144-8h6cli5d authors: Wallis, Lee A. title: African Federation for Emergency Medicine resources for managing COVID-19 in low resourced settings date: 2020-06-16 journal:
    keywords: covid-19; resources
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        item: #659 of 7819
          id: cord-254152-9wt2za3m
      author: Qiu, Chenghao
       title: Olfactory and Gustatory Dysfunction as an Early Identifier of COVID-19 in Adults and Children: An International Multicenter Study
        date: 2020-06-16
       words: 4997
      flesch: 35
     summary: symptoms in a large number of COVID-19 patients. 6 Olfactory and gustatory disorders were also found to be prevalent symptoms in COVID-19 patients in a multicenter European study.
    keywords: covid-19; data; dysfunction; gustatory; integrity; olfactory; patients; questions; work
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        item: #660 of 7819
          id: cord-254162-tu81j66h
      author: Bai, Xiyuan
       title: Hypothesis: alpha-1-antitrypsin is a promising treatment option for COVID-19
        date: 2020-11-12
       words: 5552
      flesch: 25
     summary: AAT inhibition of ADAM17 also prevents shedding of ACE2 and hence may preserve ACE2 inhibition of bradykinin, reducing the ability of bradykinin to cause a capillary leak in COVID-19. Sixth, AAT inhibition of elastase can antagonize the formation of neutrophil extracellular traps (NETs), a complex extracellular structure comprised of neutrophil-derived DNA, histones, and proteases, and implicated in the immunothrombosis of COVID-19; indeed, AAT has been shown to change the shape and adherence of non-COVID-19-related NETs.
    keywords: aat; ace2; acute; anti; antitrypsin; cov-2; covid-19; inhibition; injury; lung; neutrophil; sars
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        item: #661 of 7819
          id: cord-254166-7y58ie8q
      author: Palazzolo, Claudia
       title: Legionella pneumonia: increased risk after COVID-19 lockdown? Italy, May to June 2020
        date: 2020-07-30
       words: 1633
      flesch: 43
     summary: The case highlights the importance of strict monitoring of water and air systems immediately before reopening business or public sector buildings, and the need to consider Legionella infections among the differential diagnosis of respiratory infections after lockdown due to the ongoing COVID-19 pandemic. The case highlights the importance of strict monitoring of water and air systems immediately before reopening business or public sector buildings, and the need to consider Legionella infections among the differential diagnosis of respiratory infections after lockdown due to the ongoing COVID-19 pandemic.
    keywords: case; covid-19; legionella; pneumonia; systems; water
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        item: #662 of 7819
          id: cord-254177-jzdy1aq2
      author: Kilaru, Austin S.
       title: Return Hospital Admissions Among 1419 Covid‐19 Patients Discharged from Five US Emergency Departments
        date: 2020-08-27
       words: 1932
      flesch: 50
     summary: All rights reserved Factors associated with hospital 4 admission and critical illness among 5279 people with coronavirus disease 5 Mild or Moderate Covid-19 Implementing Home Care of People Not Requiring Hospitalization for 10 Management of Patients with Confirmed Coronavirus Disease Development and Validation of a Clinical 18 Risk Score to Predict the Occurrence of Critical Illness in Hospitalized 19 Patients With COVID-19 Clinical features of patients infected with 21 2019 novel coronavirus in Wuhan Hospitalization Rates and 24 Characteristics of Patients Hospitalized with Laboratory Coronavirus Disease 2019 -COVID-NET, 14 States 1, 5 In this study, we describe 19 the incidence of return hospital admission within 72 hours for patients with 20 Covid-19 who were discharged from the ED upon initial presentation.
    keywords: admission; hospital; patients; return
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        item: #663 of 7819
          id: cord-254191-5cxv9l3c
      author: Islam, A.K.M. Najmul
       title: Misinformation sharing and social media fatigue during COVID-19: An affordance and cognitive load perspective
        date: 2020-07-12
       words: 11924
      flesch: 44
     summary: Prior research also suggests that social media users gain social capital through communicating and self-promoting themselves in social media (de Zúñiga et al., 2017) . Caution: wit and humor during the COVID-19 pandemic A two-staged SEM-neural network approach for understanding and predicting the determinants of m-commerce adoption Labor Markets During the COVID-19 Crisis: A Preliminary View (No. w27017) Social media social capital, offline social capital, and citizenship: exploring asymmetrical social capital effects
    keywords: covid-19; et al; exploration; factors; fatigue; information; information sharing; media; misinformation; news; overload; people; self; sharing; smf; social; use
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        item: #664 of 7819
          id: cord-254218-2wsf7xix
      author: Collins, Jemima T.
       title: The Clinical Frailty Scale: Estimating the Prevalence of Frailty in Older Patients Hospitalised with COVID-19. The COPE Study
        date: 2020-09-21
       words: 2470
      flesch: 55
     summary: Association of the Clinical Frailty Scale with Hospital Outcomes Prevalence of frailty and its association with mortality in general surgery Is frailty associated with short-term outcomes for elderly patients with acute coronary syndrome? Prevalence and Postdischarge Outcomes Associated with Frailty in Medical Inpatients: Impact of Different Frailty Definitions Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: A retrospective observational study using electronic health records Clinical frailty and functional trajectories in hospitalized older adults: A retrospective observational study Identification of Frailty and Its Risk Factors in Elderly Hospitalized Patients from Different Wards: A Cross-Sectional Study in China Prevalence of Frailty at Population Level in European ADVANTAGE Joint Action Member States: A Systematic Review and Meta-Analysis Frailty in the face of COVID-19 COVID-19 and Individual Genetic Susceptibility/Receptivity: Role of ACE1/ACE2 Genes, Immunity, Inflammation and Coagulation. Our aims were to assess the prevalence of frailty in older patients hospitalised with COVID-19, their sex and age distribution, and the completion rate of the CFS tool in evaluating frailty.
    keywords: cfs; covid-19; frailty; people; prevalence
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        item: #665 of 7819
          id: cord-254222-ifsqiibv
      author: O'Connor, Rory C
       title: Multidisciplinary research priorities for the COVID-19 pandemic – Authors' reply
        date: 2020-06-18
       words: 1165
      flesch: 41
     summary: Clearly, for those who are vulnerable, it is important to be We are encouraged and stimulated by the responses to our Position Paper on COVID-19 mental health science. We need to find new ways to bring research communities together, because mental health science is best served when we join forces, complementing each other.
    keywords: covid-19; health; research
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        item: #666 of 7819
          id: cord-254228-g2mjj7my
      author: Felson, Marcus
       title: Routine activity effects of the Covid-19 pandemic on burglary in Detroit, March, 2020
        date: 2020-06-23
       words: 3981
      flesch: 57
     summary: An academic compilation by McDonald and Balkin (2020) of crime in five major North American cities added evidence of major crime declines in Chicago, San Francisco and Philadelphia. Routine activities have changed exogenously; that is, a critic could not easily justify the argument that crime declines have impelled people to stay home.
    keywords: activities; burglaries; burglary; covid-19; crime; detroit; march; period
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        item: #667 of 7819
          id: cord-254256-8jhaxcn1
      author: Ressaire, Quentin
       title: Low total cholesterol blood level is correlated with pulmonary severity in COVID-19 critical ill patients
        date: 2020-08-28
       words: 471
      flesch: 36
     summary: Rosuvastatin for Sepsis-Associated Acute Respiratory Distress Syndrome Association of Elevated Plasma Interleukin-18 Level With Increased Mortality in a Clinical Trial of Statin Treatment for Acute Respiratory Distress Syndrome*: Critical Care Medicine Serum Cytokine and Chemokine profile in Relation to the Severity of Coronavirus disease 2019 (COVID-19) in China. Exclusion criteria were age under 18, pregnancy or moribund patient at admission.
    keywords: covid-19; patients
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        item: #668 of 7819
          id: cord-254269-x8vpnhd2
      author: Hakim, Abraham A.
       title: Implications for the use of telehealth in surgical patients during the COVID-19 pandemic
        date: 2020-04-21
       words: 1322
      flesch: 44
     summary: key: cord-254269-x8vpnhd2 authors: Hakim, Abraham A.; Kellish, Alec S.; Atabek, Umur; Spitz, Francis R.; Hong, Young K. title: Implications for the use of telehealth in surgical patients during the COVID-19 pandemic date: 2020-04-21 journal: Am J Surg DOI: 10.1016/j.amjsurg.2020.04.026 sha: doc_id: Presented in this paper is a review describing the application of telemedicine in caring for surgical patients, and methods for potential implications of telehealthcare for surgical patients during the COVID-19 pandemic.
    keywords: covid-19; pandemic; patients; telehealth
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        item: #669 of 7819
          id: cord-254278-awdqguoo
      author: Khan, Suliman
       title: Association of COVID-19 infection with pregnancy outcomes in healthcare workers and general women
        date: 2020-04-08
       words: 776
      flesch: 59
     summary: Based on our findings in these seventeen patients, we suggest that COVID-19 infection 12 may lead to the occurrence of neonatal pneumonia and preterm delivery. However, we cannot In summary, we found two neonates suspected for COVID-19 infection and five neonates 1 with neonatal pneumonia, suggesting the possibility that adverse pregnancy outcomes may be 2 linked to COVID-19 infection.
    keywords: covid-19; patients
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        item: #670 of 7819
          id: cord-254287-8q2gdy5n
      author: Azoulay, Elie
       title: International variation in the management of severe COVID-19 patients
        date: 2020-08-05
       words: 1326
      flesch: 46
     summary: There are important practice variations in the management of severe COVID-19 patients, including differences at regional and individual levels. This survey highlights important practice variations in the management of severe COVID-19 patients, including differences at regional and individual levels.
    keywords: covid-19; management; patients
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        item: #671 of 7819
          id: cord-254288-duukt2wh
      author: Chew, Nicholas W.S.
       title: A multinational, multicentre study on the psychological outcomes and associated physical symptoms amongst healthcare workers during COVID-19 outbreak
        date: 2020-04-21
       words: 4457
      flesch: 39
     summary: key: cord-254288-duukt2wh authors: Chew, Nicholas W.S.; Lee, Grace K.H.; Tan, Benjamin Y.Q.; Jing, Mingxue; Goh, Yihui; Ngiam, Nicholas J.H.; Yeo, Leonard L.L.; Ahmad, Aftab; Ahmed Khan, Faheem; Napolean Shanmugam, Ganesh; Sharma, Arvind K.; Komalkumar, R.N.; Meenakshi, P.V.; Shah, Kenam; Patel, Bhargesh; Chan, Bernard P.L.; Sunny, Sibi; Chandra, Bharatendu; Ong, Jonathan J.Y.; Paliwal, Prakash R.; Wong, Lily Y.H.; Sagayanathan, Renarebecca; Chen, Jin Tao; Ying Ng, Alison Ying; Teoh, Hock Luen; Tsivgoulis, Georgios; Ho, Cyrus S.; Ho, Roger C.; Sharma, Vijay K. title: A multinational, multicentre study on the psychological outcomes and associated physical symptoms amongst healthcare workers during COVID-19 outbreak date: 2020-04-21 journal: Brain Behav Immun DOI: 10.1016/j.bbi.2020.04.049 sha: doc_id: 254288 cord_uid: duukt2wh OBJECTIVE: Since the declaration of the coronavirus 2019 (COVID-19) outbreak as pandemic, there are reports on the increased prevalence of physical symptoms observed in the general population. We investigated the association between psychological outcomes and physical symptoms among healthcare workers.
    keywords: anxiety; covid-19; depression; healthcare; outbreak; stress; study; symptoms; workers
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        item: #672 of 7819
          id: cord-254340-e1x0z3rh
      author: Cruz, Christian Joy Pattawi
       title: Exploring the young demographic profile of COVID-19 cases in Hong Kong: Evidence from migration and travel history data
        date: 2020-06-26
       words: 4969
      flesch: 57
     summary: Analysis of the travel histories of Hong Kong cases suggests that the majority of imported cases in the 15-24 age group may be Hong Kong residents who are studying or working abroad. By doing so, we highlight the importance of returnee Hong Kong residents from overseas hotspots on the relatively young age structure of confirmed cases during the second wave in March 2020.
    keywords: age; care; cases; covid-19; data; hong; hong kong; kong; population; travel
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        item: #673 of 7819
          id: cord-254377-j8e8gb0l
      author: Ali, Sadaf
       title: Acute cor pulmonale from saddle pulmonary embolism in a patient with previous Covid-19 – should we prolong prophylactic anticoagulation?
        date: 2020-06-13
       words: 1451
      flesch: 29
     summary: Clinical Characteristics of Coronavirus Disease 2019 in China Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: A Prospective Cohort Study Acute Cor Pulmonale in Critically Ill Patients with Covid-19 High risk of thrombosis in patients in severe SARS-CoV-2 infection: a multicenter prospective cohort study Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19 Thrombolytic therapy for pulmonary embolism MARVELOUS Collaborators. We report the case of a 52-year old woman, who presented with massive saddle pulmonary embolism after one week of initial hospital discharge, successfully thrombolysed that raises the question of consideration of extended prophylactic anticoagulation even in low risk Covid-19 cases.
    keywords: acute; covid-19; patients; risk; thromboembolism
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        item: #674 of 7819
          id: cord-254382-xy8se56o
      author: Santos, C.
       title: Comparative Incidence and Outcomes of COVID-19 in Kidney or Kidney-Pancreas Transplant Recipients Versus Kidney or Kidney-Pancreas Waitlisted Patients: A Pilot Study
        date: 2020-07-25
       words: 3663
      flesch: 35
     summary: We hypothesize that these patients have an incidence proportion of COVID-19 similar to the general population, but that transplanted patients have greater occurrences of hospitalization, intensive care unit admission, mechanical ventilation and death compared to waitlisted patients due to chronic immunosuppression. Supplementary oxygen was provided to 36% of transplanted patients, and 33% of waitlisted patients.
    keywords: covid-19; kidney; medrxiv; pancreas; patients; preprint; transplanted
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        item: #675 of 7819
          id: cord-254411-e9vvjv8w
      author: Taghizadeh-Hesary, Farzad
       title: The Powerful Immune System Against Powerful COVID-19: A Hypothesis
        date: 2020-04-22
       words: 1882
      flesch: 45
     summary: Immune cells are not an exception. Moreover, aging can wane the ability of immune cells to secrete IFN following viral infection (13) .
    keywords: atp; cells; covid-19; depletion; system
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        item: #676 of 7819
          id: cord-254419-qw83atrx
      author: Bhattacharyya, Rajat
       title: The Interplay Between Coagulation and Inflammation Pathways in COVID-19-Associated Respiratory Failure: A Narrative Review
        date: 2020-08-25
       words: 5908
      flesch: 29
     summary: Statins, another group of drugs that have anti-inflammatory and antithrombotic properties, have also been studied in COVID-19 patients; a retrospective study showed a favorable recovery profile and lower all-cause mortality with the use of statins in 1219 hospitalized patients with COVID-19 A pilot trial of adding tocilizumab therapy in patients with severe COVID-19 disease in combination with standard therapy of lopinavir, methylprednisolone, and oxygen therapy showed remarkable short-term clinical responses in 20 out of 21 patients within 2 weeks of tocilizumab therapy [57] .
    keywords: acute; anticoagulation; cells; coronavirus; covid-19; disease; failure; infection; inflammatory; patients; pulmonary; study; thrombosis; trials
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        item: #677 of 7819
          id: cord-254421-0lvy15q2
      author: Nahshon, Chen
       title: Author’s Reply: Hazardous Postoperative Outcomes of Unexpected COVID-19 Infected Patients: A Call for Global Consideration of Sampling All Asymptomatic Patients Before Surgical Treatment
        date: 2020-07-04
       words: 521
      flesch: 25
     summary: Importantly, higher mortality rates were documented in COVID-19 surgical patients diagnosed postoperatively. In view of the progress in diagnostic tests and the presented perilous outcomes of infected COVID-19 surgical patients, routine preoperative screening should be considered, focusing on patient and staff safety.
    keywords: covid-19; patients
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        item: #678 of 7819
          id: cord-254428-n0uwy77g
      author: Zhao, Wen
       title: Clinical characteristics and durations of hospitalized patients with COVID-19 in Beijing: a retrospective cohort study
        date: 2020-03-17
       words: 3393
      flesch: 48
     summary: In terms of discharged patients, times of illness onset to discharge and of exposure point to discharge (available in 21 patients) were 18.5 (15) (16) (17) (18) (19) (20) (21) (22) and 23 (17-25) days, respectively. In conclusion, the average hospital length of stay is 13 days for discharged patients with COVID-19; average time of clinical course is 23 days.
    keywords: covid-19; days; duration; hospital; patients; study
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        item: #679 of 7819
          id: cord-254436-89zf41xr
      author: Singer, Professor Donald RJ
       title: Health policy implications of the links between cardiovascular risk and COVID-19
        date: 2020-09-03
       words: 2004
      flesch: 44
     summary: European Centre for Disease Prevention and Control EMA to monitor real world use of COVID-19 treatments and vaccines COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives Clinical determinants for fatality of 44,672 patients with COVID-19. Health policy makers also need to take steps to extend influenza immunization to all groups now recognized to be at risk of more serious COVID-19, including the obese, others with increased cardiovascular risk and people from black and other at risk ethnic minorities.
    keywords: covid-19; disease; health; patients; risk
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        item: #680 of 7819
          id: cord-254446-yxqbe1dj
      author: Ren, Yunzhao R.
       title: A Comprehensive Updated Review on SARS‐CoV‐2 and COVID‐19
        date: 2020-05-29
       words: 6750
      flesch: 32
     summary: One study reported that IFN-γ, TNF-α, IL-1β, and IL-8 plasma concentrations in COVID-19 patients were significantly higher compared to results from four healthy In addition to the consistent trend of lower lymphocyte counts observed in severe cases of COVID-19 (Table 3 ) from different studies, total T cells, CD4 + T cells, and CD8 + T cells also were significantly lower in severe/critical COVID-19 cases than in non-severe cases 124, 127, 128 . They also found that CD8 + T cells in COVID-19 patients exhibit many aspects of exhaustion and reduced function, such as Once in the cell, the virus is not killed or neutralized; instead, it may continue to replicate, and/or stimulate or kill the target cells, causing more inflammation and damage.
    keywords: analysis; cases; china; coronavirus; cov-2; covid-19; days; disease; infection; novel; patients; pneumonia; review; sars; study; syndrome; transmission
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        item: #681 of 7819
          id: cord-254449-ww7iq04j
      author: Naithani, Nardeep
       title: COVID-19: Shades of Grey
        date: 2020-05-20
       words: 1364
      flesch: 60
     summary: Influenza Other Respir Viruses WHO Director-General's opening remarks at the media briefing on COVID-19 The missing pieces in the jigsaw and need for cohesive research amidst COVID 19 global response A skeptic's guide to ecologic studies during a pandemic Data-based analysis, modelling and forecasting of the COVID-19 outbreak Healthcare impact of COVID-19 epidemic in India: a stochastic mathematical model Predictive mathematical models of the COVID-19 pandemic: Underlying principles and value of projections Ist 2020 11:27. The name quarantine rings an alarm with reports of people escaping quarantine and stamping of COVID-19 suspects by authorities.
    keywords: covid-19; india; pandemic; world
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        item: #682 of 7819
          id: cord-254452-gqqdx2r5
      author: Singh, Awadhesh Kumar
       title: Remdesivir in COVID-19: A critical review of pharmacology, pre-clinical and clinical studies
        date: 2020-05-12
       words: 3178
      flesch: 40
     summary: In the first double-blind, placebo-controlled, randomized trial (DBRCT) conducted with remdesivir versus placebo (n=236) in severe COVID-19 patients, In non-clinical reproductive toxicity studies, no adverse effect on embryo-fetal development in pregnant animal or male infertility observed with remdesivir, however at a systematically toxic dose an embryonic toxicity was seen.
    keywords: clinical; covid-19; days; patients; remdesivir; sars; trial
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        item: #683 of 7819
          id: cord-254456-d79z01jh
      author: Juergens, Carsten
       title: Trustworthy COVID-19 Mapping: Geo-spatial Data Literacy Aspects of Choropleth Maps
        date: 2020-10-23
       words: 2541
      flesch: 48
     summary: key: cord-254456-d79z01jh authors: Juergens, Carsten title: Trustworthy COVID-19 Mapping: Geo-spatial Data Literacy Aspects of Choropleth Maps date: 2020-10-23 journal: KN J Cartogr Geogr Inf DOI: 10.1007/s42489-020-00057-w sha: doc_id: 254456 cord_uid: d79z01jh Since the COVID-19 (coronavirus disease 2019) pandemic is a global phenomenon, many scientists and research organizations create thematic maps to visualize and understand the spatial spread of the disease and to inform mankind. This contribution intends to make people of disciplines other than those that are map-related aware of the power of thematic maps and how one can create trustworthy thematic maps instead of misleading thematic maps which could, in a worst case, lead to misinterpretation. GIS and web-mapping technologies play an essential role to provide rapid visualization of the geo-spatial spread of the SARS-CoV-2/COVID-19 pandemic (e.g. Zhou et al. 2020; Rosenkrantz et al. 2020) .
    keywords: choropleth; color; covid-19; data; geo; map; maps
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        item: #684 of 7819
          id: cord-254458-bbcef8xt
      author: Ali, Farhana
       title: Throat Wash Testing and COVID-19 Disease: Should We Put Our Money Where Our Mouth Is?
        date: 2020-04-30
       words: 1110
      flesch: 48
     summary: Admittedly, the sensitivity of throat wash testing almost seems too good to be true; nonetheless, the ramifications of failing to identify COVID-19 positive patients would have dire consequences amid a pandemic. Similarly, there have also been shortages of nasopharyngeal swabs, leading to delays in COVID-19 testing [7] .
    keywords: covid-19; testing
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        item: #685 of 7819
          id: cord-254464-6l7fwylu
      author: Shingare, Ashay
       title: COVID‐19 in recent kidney transplant recipients
        date: 2020-06-08
       words: 1712
      flesch: 47
     summary: Due to intensive immunosuppression, recent transplant recipients (< 3 months post-transplant) are at increased risk of developing severe disease due to COVID-19. Our recent LDKT recipients had minimal symptoms and no allograft dysfunction after developing COVID-19. Mortality and complications in recent transplant recipients with COVID-19 may be low in Asian populations, but more data is required to say so.
    keywords: covid-19; day; kidney; recipients; transplant
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        item: #686 of 7819
          id: cord-254465-y8n7t8rx
      author: Soulat-Dufour, Laurie
       title: Left ventricular ejection fraction: an additional risk marker in COVID-19
        date: 2020-10-19
       words: 638
      flesch: 34
     summary: r o o f Early identification of patients at high risk of death from COVID-19 Beyond the complexity of the mechanisms of cardiac involvement in patients with SARS-CoV-2 pneumonia, the non-invasive evaluation of left ventricular function, while respecting protection rules and precautions, could be a simple parameter to refine their short-term prognosis.
    keywords: covid-19; patients
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        item: #687 of 7819
          id: cord-254469-7q6xi2xx
      author: Wang, Fuzhou
       title: An Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development
        date: 2020-05-05
       words: 4743
      flesch: 40
     summary: Therefore, further in-depth studies are needed to elucidate the structure and corresponding physiological and immunological properties of the S protein and also other structural proteins that have a potential role in vaccine development, including mRNA based vaccines. The spike glycoprotein (S protein) is now a key target for vaccine development, therapeutic antibody generation, and the clinical diagnosis of COVID-19.
    keywords: ace2; coronavirus; cov-2; covid-19; development; mrna; protein; s protein; sars; vaccine; virus
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        item: #688 of 7819
          id: cord-254475-rdimnsmo
      author: Johnson, S. S.
       title: Excess Risk of COVID-19 to University Populations Resulting from In-Person Sporting Events
        date: 2020-09-28
       words: 4523
      flesch: 42
     summary: The median of the 25 simulations with events was then divided by the median of the 25 simulations without to provide an estimate of the relative increase in COVID-19 cases due to events. Distribution of cumulative COVID-19 cases in 1,000 simulated university campuses with controlled epidemics, comparing a campus with no in-person sporting events to two scenarios where visitors come from a low prevalence area and mix with the campus community at a low rate or a high rate respectively. .
    keywords: campus; cases; covid-19; events; license; preprint; visitors
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        item: #689 of 7819
          id: cord-254494-wbfgrez1
      author: Shi, Chunhong
       title: Barriers to Self-Management of Type 2 Diabetes During COVID-19 Medical Isolation: A Qualitative Study
        date: 2020-10-14
       words: 5755
      flesch: 39
     summary: The purpose of this study was to explore perceived barriers among type 2 diabetes patients during isolation following their recovery from COVID-19. Perceived barriers to diabetes self-management described by diabetes patients indicated a lack of environmental resources and support strategies to meet their needs.
    keywords: barriers; blood; covid-19; diabetes; isolation; management; participants; patients; self; study; support
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        item: #690 of 7819
          id: cord-254497-8bhahzys
      author: Abdelnabi, Mahmoud
       title: Coronavirus Disease 2019 Myocarditis: Insights into Pathophysiology and Management
        date: 2020-06-17
       words: 649
      flesch: 30
     summary: 5 Interestingly, three case reports have noted successful management of COVID-19 fulminant myocarditis using mainly immune-modulators and supportive measures. 8 Hu et al. described successful management of fulminant myocarditis using methylprednisolone, immunoglobulin, inotropes and diuretics with gradual improvement of LVEF and cardiac biomarkers over several weeks.
    keywords: covid-19; myocarditis
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        item: #691 of 7819
          id: cord-254538-vcf44w1k
      author: Rocha Filho, C. R.
       title: PROGNOSTIC FACTORS FOR CLINICAL COURSE OF PATIENTS WITH COVID-19: PROTOCOL FOR A RAPID LIVING SYSTEMATIC REVIEW
        date: 2020-05-09
       words: 2560
      flesch: 55
     summary: We will perform the critical appraisal of included studies with the Quality in Prognosis Studies (QUIPS) tool and the certainty of evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE). A predefined form will be used to extract data from included studies.
    keywords: 2019; coronavírus; covid-19; por; preprint; studies
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        item: #692 of 7819
          id: cord-254591-z9rfwm1g
      author: Vasconcelos, G. L.
       title: Modelling the epidemic growth of preprints on COVID-19 and SARS-CoV-2
        date: 2020-09-09
       words: 4865
      flesch: 49
     summary: For example, a recent bibliometric analysis [5] of COVID-19 related preprints concluded that the faster rate with which they are posted on preprint repositories have only limited impact on the quality of preprints that are subsequently published. We also analyze the rank-frequency distribution of preprints servers, ordered by the number of COVID-19 preprints they host, and find that it follows a power-law decay.
    keywords: covid-19; curve; growth; medrxiv; number; preprints; time
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        item: #693 of 7819
          id: cord-254621-ub7ynjai
      author: Hoyer, Carolin
       title: Decreased utilization of mental health emergency service during the COVID-19 pandemic
        date: 2020-06-09
       words: 1393
      flesch: 32
     summary: key: cord-254621-ub7ynjai authors: Hoyer, Carolin; Ebert, Anne; Szabo, Kristina; Platten, Michael; Meyer-Lindenberg, Andreas; Kranaster, Laura title: Decreased utilization of mental health emergency service during the COVID-19 pandemic date: 2020-06-09 journal: This retrospective study aimed to quantify the dynamics of mental health emergency service utilization during the COVID-19 pandemic and to assess a potential impact of the partial lockdown in Germany.
    keywords: covid-19; emergency; pandemic; service
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        item: #694 of 7819
          id: cord-254628-706vpjsv
      author: Stewart, Claire R.
       title: Safeguarding Dermatologist Attendings and Residents Amid the COVID‐19 Pandemic: Focus on Special Populations
        date: 2020-06-03
       words: 653
      flesch: 41
     summary: As stay at home orders expire, delayed surgeries and in-person semi-urgent appointments will be scheduled, with increased patient volume and heightened COVID-19 infection risk. Despite appropriate precautions to reduce transmission risk, many dermatology faculty, residents, staff, and their families are at increased risk for COVID-19 infection while caring for patients.
    keywords: covid-19; residents; risk
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        item: #695 of 7819
          id: cord-254631-80sg4uvd
      author: Llansó, Laura
       title: Posterior Reversible Encephalopathy Syndrome in COVID-19 Disease: a Case-Report
        date: 2020-08-26
       words: 1037
      flesch: 32
     summary: We report a case of posterior reversible encephalopathy syndrome in a patient with COVID-19 disease, possibly related to anti-IL-1 or anti-IL-6, suggesting that anti-interleukin treatments may cause this syndrome, at least in patients with predisposing conditions such as infections and hydroelectrolytic disorders. Considering the infectious background, the immunomodulatory treatments, modest hypertension in the hours before the symptoms, and the distribution of the lesions on the CT scan, the most likely diagnosis is posterior reversible encephalopathy syndrome (PRES)
    keywords: anti; blood; pres; syndrome
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        item: #696 of 7819
          id: cord-254653-4ffuivil
      author: Cinelli, Matteo
       title: The COVID-19 social media infodemic
        date: 2020-10-06
       words: 5102
      flesch: 43
     summary: Thus, social media platforms seem to have specific timings for content consumption; such patterns may depend upon the difference in terms of audience and interaction mechanisms (both social and algorithmic) among platforms. We observe that the amplification E U (for unreliable posts posts produced by questionable outlets) and E R (for reliable posts www.nature.com/scientificreports/ posts produced by reliable outlets) vary from social media platform to social media platform and that assumes the largest values in YouTube and the lowest in Gab.
    keywords: covid-19; information; media; model; news; number; outlets; platform; posts; social; sources
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        item: #697 of 7819
          id: cord-254667-yafcy8ul
      author: Sisto, Antonella
       title: The psychological impact of COVID-19 pandemic on patients included in a bariatric surgery program
        date: 2020-08-28
       words: 4658
      flesch: 34
     summary: Univariate and multivariate binary logistic regression analysis of COVID-19 related psychological markers of depression, anxiety and stress on post-bariatric subjects are summarized in Table 4 . Logistic regression analysis on post-bariatric patients showed a relationship between snacking, hunger, eating impulsivity, and anxiety, stress, and/or depression symptoms.
    keywords: anxiety; covid-19; depression; eating; patients; stress; surgery; table
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        item: #698 of 7819
          id: cord-254686-pclq855r
      author: Sanmugam, Anand
       title: Assess, adapt and act: a paediatric surgery division’s initial approach in a rapidly evolving pandemic
        date: 2020-06-27
       words: 3005
      flesch: 39
     summary: Being a key provider of paediatric surgical services and training in a developing country, several changes to aspects of patient care and approaches to surgical training were adopted. The biggest challenge we faced were to formulate a set of guidelines that ensured the safety of patients and healthcare personnel alike, at a time when there was limited published literature on the delivery of paediatric surgical service during a pandemic.
    keywords: covid-19; division; hospital; pandemic; patients; services; surgery; training
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        item: #699 of 7819
          id: cord-254687-g9tptfna
      author: Nani, Fernando Souza
       title: Ulcer pressure prevention and opportunity for innovation during the COVID-19 crisis
        date: 2020-08-28
       words: 791
      flesch: 29
     summary: key: cord-254687-g9tptfna authors: Nani, Fernando Souza; Stéfani, Kelly Cristina; Busnardo, Fabio de Freitas; Monteiro, Gustavo Gomes Ribeiro; dos Santos, Maria Gabriela Guimarães Ribeiro; John, Vanderley Moacyr; Gouvêa, Douglas; Carmona, Maria José C. title: Ulcer pressure prevention and opportunity for innovation during the COVID-19 crisis date: 2020-08-28 journal: Clinics (Sao Paulo) DOI: 10.6061/clinics/2020/e2292 sha: doc_id: 254687 cord_uid: g9tptfna nan The coronavirus disease (COVID-19) pandemic has put the health system under stress in many places around the world. The new scenario led to the challenge of pressure ulcer prevention.
    keywords: covid-19; position; pressure; prevention
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        item: #700 of 7819
          id: cord-254715-4dt8aqof
      author: Kander, Thomas
       title: Coagulation disorder in COVID-19
        date: 2020-07-10
       words: 876
      flesch: 19
     summary: Further, COVID-19 infection is associated with coagulopathy of varying degrees, similar to the changes observed in sepsis induced coagulopathy (SIC) or disseminated intravascular coagulopathy (DIC). Furthermore, severe COVID-19 infection might also lead to a cytokine storm similar to the cytokine profile present in secondary haemophagocytic lymphohistiocytosis, including increased ferritin level, IL-1, IL-2, IL-6, IL-7, granulocyte-colony stimulating factor, interferon-γ inducible protein 10, monocyte chemoattractant protein 1, macrophage inflammatory protein 1-α, and tumour necrosis factor-α. 4, 5 In The Lancet Haematology, Danying Liao and colleagues 6 were independently associated with increased mortality in a linear mixed model comparing survivors and nonsurvivors.
    keywords: coagulation; covid-19; patients
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        item: #701 of 7819
          id: cord-254727-d1pgjtjh
      author: Shao, Fei
       title: In-hospital cardiac arrest outcomes among patients with COVID-19 pneumonia in Wuhan, China
        date: 2020-04-10
       words: 2987
      flesch: 46
     summary: In total, 800 beds were modified as isolation wards and opened for admission to severe patients with COVID-19 pneumonia starting from January 2020. key: cord-254727-d1pgjtjh authors: Shao, Fei; Xu, Shuang; Ma, Xuedi; Xu, Zhouming; Lyu, Jiayou; Ng, Michael; Cui, Hao; Yu, Changxiao; Zhang, Qing; Sun, Peng; Tang, Ziren title: In-hospital cardiac arrest outcomes among patients with COVID-19 pneumonia in Wuhan, China date: 2020-04-10 journal: Resuscitation DOI: 10.1016/j.resuscitation.2020.04.005 sha: doc_id: 254727 cord_uid: d1pgjtjh OBJECTIVE:
    keywords: cardiac; covid-19; hospital; ihca; patients; pneumonia; resuscitation
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        item: #702 of 7819
          id: cord-254737-pv68fb7d
      author: Imtyaz, Ayman
       title: Analysing governmental response to the COVID-19 pandemic
        date: 2020-08-14
       words: 3416
      flesch: 59
     summary: Unlike other countries in the top cases list, Sweden did not implement a lockdown. Much like other countries in Africa, South Africa also has a large proportion of young people who may help offset the mortality rate.
    keywords: cases; countries; data; mortality; rate; testing; virus
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        item: #703 of 7819
          id: cord-254740-o80ssdrw
      author: McCann, Shaun R.
       title: COVID-19, HCT and wine
        date: 2020-05-06
       words: 975
      flesch: 58
     summary: Another side of the coin is that many seasonal workers play a very important role in the economy of their country of origin by sending money home like thousands of Italians and Irish did in the early 20th century. I have not personally examined the living conditions of seasonal workers but would be surprised if they are pristine and social distancing possible.
    keywords: covid-19; patients; society; wine
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        item: #704 of 7819
          id: cord-254758-ubw0chrf
      author: Newbold, Stephen C.
       title: Effects of Physical Distancing to Control COVID-19 on Public Health, the Economy, and the Environment
        date: 2020-08-04
       words: 10218
      flesch: 40
     summary: The results from our control model presented in this paper suggest that there may be important environmental side-effects that could alter the optimal intensity and duration of physical distancing policies used to manage the COVID-19 epidemic. In an application to the United States, our model considers the trade-off between the lives saved by physical distancing—both directly from stemming the spread of the virus and indirectly from reductions in air pollution during the period of physical distancing—and the short- and long-run economic costs that ensue from such measures.
    keywords: air pollution; benefits; case; control; covid-19; deaths; distancing; et al; fatality; health; infections; model; number; policy; time; value
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        item: #705 of 7819
          id: cord-254771-698gl09v
      author: Ferriss, J. Stuart
       title: Society of Gynecologic Oncology recommendations for fellowship education during the COVID-19 pandemic and beyond: Innovating programs to optimize trainee success
        date: 2020-10-17
       words: 7566
      flesch: 41
     summary: Fellowship education programs in gynecologic oncology have quickly adapted to the “new normal” of social distancing using video conferencing platforms to continue clinical and didactic teaching. Fellowship education programs in gynecologic oncology have quickly adapted to the new normal of social distancing using video conferencing platforms to continue clinical and didactic teaching.
    keywords: care; covid-19; education; faculty; fellows; fellowship; gynecologic; interview; learning; oncology; pandemic; program; research; time; training; video
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        item: #706 of 7819
          id: cord-254776-m4makxr8
      author: Luo, Shiua
       title: A Follow-up Study of Recovered Patients with COVID-19 in Wuhan, China
        date: 2020-06-01
       words: 385
      flesch: 54
     summary: The Chinese government has taken serious actions and made unremitted efforts in prevention and control of COVID-19 epidemic, including imposing quarantines and travel restrictions on an unprecedented scale and investing a huge amount of medical resources [2] . Currently, a large number of COVID-19 patients in Wuhan have been cured and discharged.
    keywords: covid-19; patients
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        item: #707 of 7819
          id: cord-254777-h8hw4m9f
      author: Tanner, Tamara
       title: Hyperinflammation and the utility of immunomodulatory medications in children with COVID-19
        date: 2020-07-29
       words: 4735
      flesch: 38
     summary: The Lancet Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease A retrospective cohort study of methylprednisolone therapy in severe patients with COVID-19 pneumonia Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Potential benefits of precise corticosteroids therapy for severe 2019-nCoV pneumonia Translating IL-6 biology into effective treatments Interleukin-6 as a therapeutic target Effective treatment of severe COVID-19 patients with tocilizumab Tocilizumab therapy reduced intensive care unit admissions and/or mortality in COVID-19 patients Interleukin-6 blockade for severe COVID-19. Similarly, an observational cohort study from the United States (US) describes shortness of breath, fever and cough as the most common presenting symptoms of patients hospitalized with COVID-19 infection
    keywords: children; coronavirus; covid-19; cytokine; disease; il-6; infection; patients; sars; treatment; use
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        item: #708 of 7819
          id: cord-254782-fzuasf2o
      author: Tadesse, Degena Bahrey
       title: Knowledge, attitude, practice and psychological response toward COVID-19 among nurses during the COVID-19 outbreak in Northern Ethiopia, 2020
        date: 2020-10-14
       words: 1401
      flesch: 51
     summary: Of the 415 nurses, 307 (74%), 278 (67%), 299 (72%), and 354 (85.3%) had good knowledge, good infection prevention practice, a favorable attitude, and disturbed psychological response towards COVID-19, respectively. Psychological response to COVID-19 96 The question regarding the psychological response was nine (with minimum score 9 and 97 maximum score 36).
    keywords: covid-19; knowledge; nurses; score
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        item: #709 of 7819
          id: cord-254796-wzb6qv7y
      author: Ford, James S.
       title: Testing Asymptomatic Emergency Department Patients for Coronavirus of 2019 (COVID‐19) in a Low Prevalence Region
        date: 2020-06-09
       words: 1645
      flesch: 43
     summary: In our study population, we found a very low true positive rate among asymptomatic patients undergoing testing. Furthermore, while the utility of screening asymptomatic individuals has been explored in high-prevalence regions, studies have not been published for low-prevalence regions 6, 7 .In the present study, we aimed to describe screening for COVID-19 in asymptomatic ED patients in a low-prevalence region.
    keywords: asymptomatic; covid-19; patients; study
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        item: #710 of 7819
          id: cord-254809-o454k6ae
      author: He, Bing
       title: The Metabolic Changes and Immune Profiles in Patients With COVID-19
        date: 2020-08-28
       words: 4764
      flesch: 55
     summary: Serum D-dimer and FDP were 9.89 mg/L (IQR, 3.62–22.85) and 32.7 mg/L (IQR, 12.8–81.9), and a large number of RBC (46/μL (IQR, 4–242) was presented in urine, a cue of disseminated intravascular coagulation (DIC) in severe patients. (D) serum IL-6 concentration between mild patients (n = 32) and severe patients (n = 21).
    keywords: cases; cells; children; covid-19; infection; iqr; monocytes; patients
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        item: #711 of 7819
          id: cord-254817-e1niin4m
      author: Solomon, Daniel H.
       title: The “Infodemic” of COVID‐19
        date: 2020-08-02
       words: 1819
      flesch: 49
     summary: Many authors of COVID-19 papers can offer how the traditional review process did not work for them. Nevertheless, A&R responded, and COVID-19 papers (82 papers through July 27, 2020) have had a first decision in an average of 7 days.
    keywords: a&r; covid-19; hydroxychloroquine; patients; science
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        item: #712 of 7819
          id: cord-254825-c5d0wul9
      author: Kim, Sei Won
       title: Containment of a healthcare-associated COVID-19 outbreak in a university hospital in Seoul, Korea: A single-center experience
        date: 2020-08-14
       words: 3562
      flesch: 46
     summary: Severe symptoms develop in approximately 14% of COVID-19 patients, and the overall mortality is around 2% of confirmed COVID-19 cases [10] . Contact was defined as presence in the same room with COVID-19 confirmed patients, or in the same outpatient clinic or examination room, 30 minutes before and after COVID-19 confirmed patients.
    keywords: contact; cov-2; covid-19; hospital; outbreak; patients; pcr; sars
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        item: #713 of 7819
          id: cord-254837-zhxabt66
      author: Giorgi, P. D.
       title: Vertebral compression fractures in multiple myeloma: redefining the priorities during the COVID-19 pandemic
        date: 2020-05-14
       words: 1650
      flesch: 41
     summary: Indeed, bone involvement is the main cause of morbidity and mortality in MM patients [3] . In this dreadful situation, standard medical practice was markedly affected, giving priority to the treatment of COVID-19 patients, while maintaining regular care only for urgent non-COVID conditions.
    keywords: covid-19; kyphoplasty; pain; patient; treatment
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        item: #714 of 7819
          id: cord-254896-e6k1bp9n
      author: Posch, Martin
       title: Analysis of Austrian COVID-19 deaths by age and sex
        date: 2020-07-03
       words: 2010
      flesch: 56
     summary: But also in Austria, increased death rates, especially among the elderly, have been reported recently [8] . If we compare this normal mortality risk with the COVID-19 mortality until 31 March or 21 April, respectively ( Fig. 2a and b) , we see a similar increase (although the number of COVID-19 deaths registered by the respective survey date scaled to the population size is orders of magnitude lower than the annual mortality rates).
    keywords: age; covid-19; mortality; risk
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        item: #715 of 7819
          id: cord-254919-fi3inp67
      author: Molina, Melanie F.
       title: Nitrous oxide inhalant abuse and massive pulmonary embolism in COVID-19
        date: 2020-05-16
       words: 696
      flesch: 40
     summary: key: cord-254919-fi3inp67 authors: Molina, Melanie F.; Al Saud, Ahad A.; Al Mulhim, Abdullah A.; Liteplo, Andrew S.; Shokoohi, Hamid title: Nitrous oxide inhalant abuse and massive pulmonary embolism in COVID-19 date: 2020-05-16 journal: Am J Emerg Med DOI: 10.1016/j.ajem.2020.05.023 sha: doc_id: 254919 cord_uid: fi3inp67 A patient presented to the emergency department with altered mental status and lower extremity weakness in the setting of nitrous oxide inhalant abuse and Coronavirus Disease-2019 (COVID-19) infection. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up Pulmonary embolism and deep vein thrombosis caused by nitrous oxide abuse: A case report Aortic arch thrombus caused by nitrous oxide abuse
    keywords: covid-19
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        item: #716 of 7819
          id: cord-254944-9f3wkvxp
      author: Pollak, Y.
       title: Background and concurrent factors predicting non-adherence to public health preventive measures during the chronic phase of the COVID-19 pandemic
        date: 2020-10-14
       words: 3240
      flesch: 44
     summary: key: cord-254944-9f3wkvxp authors: Pollak, Y.; Shoham, R.; Dayan, H.; Gabrieli Seri, O.; Berger, I. title: Background and concurrent factors predicting non-adherence to public health preventive measures during the chronic phase of the COVID-19 pandemic date: 2020-10-14 journal: nan DOI: 10.1101/2020.10.13.20211904 sha: doc_id: 254944 cord_uid: 9f3wkvxp To determine factors that predict non-adherence to preventive measures for COVID-19 during the chronic phase of the pandemic, a cross-sectional, general population survey was conducted in Israel. COVID-19 perception variables: Non-APM was predicted by higher perceived non-adherence norms, lower perceived risk of COVID-19, lower perceived efficacy of the preventive measures, as well as higher perceived costs of adherence.
    keywords: adherence; apm; covid-19; measures; non; preprint; risk
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        item: #717 of 7819
          id: cord-254967-r7c0pxep
      author: Lai, Xue-Li
       title: Recommendations for prevention and management of COVID-19 in peritoneal dialysis patients
        date: 2020-05-04
       words: 1670
      flesch: 47
     summary: In contrast, PD patients have a weakened immune system that is associated with a high morbidity of infection. PD patients and caregivers are familiar with aseptic techniques as they are performed during and after PD procedures.
    keywords: cov-2; covid-19; patients; sars
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        item: #718 of 7819
          id: cord-254990-nrzwn6oz
      author: Mayer, Kirby P.
       title: Recovery from COVID-19 and acute respiratory distress syndrome: the potential role of an intensive care unit recovery clinic: a case report
        date: 2020-09-10
       words: 3124
      flesch: 43
     summary: Coronavirus disease 2019 (COVID-19) pandemic Reference equations for the six-minute walk in healthy adults Survival rate in acute kidney injury superimposed COVID-19 patients: a systematic review and meta-analysis Implementation of an ICU recovery clinic at a tertiary care academic center Comprehensive care of ICU survivors: development and implementation of an ICU recovery center CE: critical care recovery center: an innovative collaborative care model for ICU survivors The ICU follow-up clinic: a new paradigm for intensivists Chaos theory: optimizing critical illness outcomes through the family experience -a theoretical review Clinical practice guidelines for support of the family in the patient-centered intensive care unit: American College of Critical Care Medicine Task Force Family response to critical illness: postintensive care syndrome -family Key components of ICU recovery programs: what did patients report provided benefit? Physical function impairment in survivors of critical illness in an ICU recovery clinic Understanding, compliance and psychological impact of the SARS quarantine experience The psychological impact of quarantine and how to reduce it: rapid review of the evidence Comprehensive review of mask utility and challenges during the COVID-19 pandemic Public health measures and the reproduction number of SARS-CoV-2 Depressive symptoms and impaired physical function after acute lung injury: a 2-year longitudinal study Physical complications in acute lung injury survivors: a two-year longitudinal prospective study Functional disability 5 years after acute respiratory distress syndrome Depression, post-traumatic stress disorder, and functional disability in survivors of critical illness in the BRAIN-ICU study: a longitudinal cohort study Co-occurrence of post-intensive care syndrome problems among 406 survivors of critical illness Scoping review of prevalence of neurologic comorbidities in patients hospitalized for COVID-19 Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations The purpose of this case report is to highlight the potential role of intensive care unit recovery or follow-up clinics for patients surviving acute hospitalization for coronavirus disease 2019.
    keywords: care; clinic; covid-19; day; follow; icu; patient; recovery; unit
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        item: #719 of 7819
          id: cord-254993-bndl93qr
      author: Sonnweber, Thomas
       title: Persisting alterations of iron homeostasis in COVID-19 are associated with non-resolving lung pathologies and poor patients’ performance: a prospective observational cohort study
        date: 2020-10-21
       words: 3690
      flesch: 34
     summary: It has been suggested that the COVID-19 related inflammation may be the main cause of COVID-19 associated iron disorders, as an inflammation-driven dysregulation of iron homeostasis is well established [4, 6, 7] . Inflammation, therefore, causes alterations of iron homeostasis hallmarked by functional iron deficiency (ID) as reflected by high iron content in reticuloendothelial cells and consequently high serum ferritin levels whereas circulating iron levels are low.
    keywords: covid-19; disease; expression; ferritin; homeostasis; hyperferritinemia; inflammation; iron; patients; serum
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        item: #720 of 7819
          id: cord-255047-0kr4y753
      author: Goletti, Orlando
       title: Factors Affecting Mortality in 1022 COVID-19 Patients Referred to an Emergency Department in Bergamo during the Peak of the Pandemic
        date: 2020-08-17
       words: 2469
      flesch: 40
     summary: Patients who were treated in AAUL-2 had a fatal event within 48 h (median 1 day, range 0-2), while patients admitted in the COVID department or in ICU died within 24 days (median 6 days, range 0-24). Patients deceased in AAUL-2 resulted in the worst conditions in comparison with patients who died in the ICU and in COVID-19 department, and their prognostic parameters reflect the situation.
    keywords: aaul-2; covid-19; department; icu; patients
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        item: #721 of 7819
          id: cord-255101-l5ssz750
      author: Daval, Mary
       title: Efficacy of local budesonide therapy in the management of persistent hyposmia in COVID-19 patients without signs of severity: A structured summary of a study protocol for a randomised controlled trial
        date: 2020-07-20
       words: 8952
      flesch: 48
     summary: Tout EIG doit être notifié au promoteur :  à partir de la date de signature du consentement,  jusqu'à la fin de participation à la recherche, mais également sans limitation de temps, lorsque l'EIG est susceptible d'être dû au médicament. Objectif principal: Evaluer l'efficacité du budésonide en traitement local intranasal (lavage de nez), en complément de la rééducation olfactive, dans la prise en charge de la perte d'odorat de patients COVID-19 sans signes de gravité et présentant une persistance de l'hyposmie 30 jours après le début des symptômes.
    keywords: budésonide; cas; cette; covid-19; d'un; dans; des; données; début; est; jours; l'étude; les; nez; non; olfactive; par; pas; patients; pour; promoteur; que; qui; recherche; sans; sera; seront; signes; sur; symptômes; traitement; une
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        item: #722 of 7819
          id: cord-255103-ckecol7i
      author: Lau, Hien
       title: Evaluating the massive underreporting and undertesting of COVID-19 cases in multiple global epicenters
        date: 2020-06-06
       words: 1685
      flesch: 52
     summary: When estimating the real total amount of COVID-19 cases using the cCFR value of Germany as the standard, a considerable increase in COVID-19 case numbers compared to total reported cases is observed. Differences in testing availability and capacity, containment as well as overall health care and medical infrastructure result in significantly different mortality rates and COVID-19 case numbers for each respective country.
    keywords: cases; countries; covid-19; numbers
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        item: #723 of 7819
          id: cord-255119-l82o5fif
      author: Passerini, Giorgio
       title: A Preliminary Investigation on the Statistical Correlations between SARS-CoV-2 Spread and Local Meteorology
        date: 2020-06-05
       words: 7633
      flesch: 48
     summary: [20] have observed negative correlations between outdoor temperature and SARS-CoV-2 infectivity statistically significant for provinces with a median temperature of −2.9 • C. Moreover, increases in daily mean temperature between 3 and 21 • C did not affect the containment of the COVID-19 outbreak in Wuhan (China) Strong negative correlations were observed between the moving means of new cases and relative humidity values for four provinces and more than 90% of the contagions.
    keywords: cases; covid-19; humidity; mean; moving; new; number; temperature; time
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        item: #724 of 7819
          id: cord-255149-mqsk7kiz
      author: Gupta, Nikhil
       title: It Will Be a Different World for Surgeons Post-COVID-19 Lockdown
        date: 2020-05-26
       words: 501
      flesch: 63
     summary: Risk of patient acquiring this infection from hospital and health care workers will have to be informed to patients and it will find its place in consent form also [2] . Whether patient can demand test report of surgeon and other health care workers?
    keywords: covid-19; surgeons
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        item: #725 of 7819
          id: cord-255173-69t521o3
      author: Papa, Annalisa
       title: Not all that glitters is COVID! Differential diagnosis of FDG-avid interstitial lung disease in low-prevalence regions
        date: 2020-10-19
       words: 1741
      flesch: 29
     summary: The role of 18F-FDG PET for COVID-19 infection: myth versus reality A comparison of clinical and chest CT findings in patients with influenza A (H1N1) virus infection and coronavirus disease (COVID-19) Authors' contributions Patient referral, image acquisition, and clinical data collection: AP and FR. The main radiological features of COVID-19 pneumonia include multifocal or diffuse bilateral ground-glass opacities (GGOs) and crazy-paving pattern with a predominant subpleural distribution (Hani et al. 2020; Salehi et al. 2020) .
    keywords: covid-19; fdg; patients
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        item: #726 of 7819
          id: cord-255204-3qruat3s
      author: Osborne, Vicki
       title: Lopinavir-Ritonavir in the Treatment of COVID-19: A Dynamic Systematic Benefit-Risk Assessment
        date: 2020-06-23
       words: 5270
      flesch: 43
     summary: Risk data suggested a possible decrease in serious adverse events. Risk data were mainly available from the Cao et al. trial, which reported fewer serious adverse events in patients taking LPVr (20%) compared to standard of care (32%).
    keywords: assessment; benefit; care; covid-19; data; lpvr; patients; risk; standard; treatment
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        item: #727 of 7819
          id: cord-255208-rbko9ecz
      author: Stevens, Ryan W.
       title: Time to Treat: Applying Lessons Learned from Other Viral Syndromes to SARS-CoV-2
        date: 2020-10-12
       words: 2049
      flesch: 34
     summary: When time to therapy was incorporated into statistical analysis, patients designated J o u r n a l P r e -p r o o f 5 -Stevens in early therapy groups still often had prolonged (i.e. 7-12 days) time to therapy initiation or the analysis did not account for the time since symptom onset until presentation. In this study the median time to therapy initiation from symptom onset was 10 days (IQR 9-12).
    keywords: days; initiation; patients; therapy; time
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        item: #728 of 7819
          id: cord-255221-v4r2ek6a
      author: Di Lorenzo, Giuseppe
       title: Coronavirus Disease (COVID-19) in Italy: Analysis of Risk Factors and Proposed Remedial Measures
        date: 2020-04-09
       words: 2192
      flesch: 48
     summary: Based on research by the WHO, a Report of the WHO China Joint Mission on Coronavirus Disease 2019, published in February 2020, reported that patients without other comorbidities have mortality rates of 1.4%, compared to COVID-19 patients with other diseases that compromise their health condition and result in higher mortality rates, which were 13, 9, and 7.6% for those with cardiovascular disease, diabetes, and cancer, respectively 5 . In the TOCIVID-19 trial, 330 hospitalized COVID-19 patients with pneumonia with early signs of respiratory failure or who were intubated and placed on ventilatory treatment within the previous 24 h will be treated with tocilizumab 10 .
    keywords: cases; covid-19; deaths; italy; patients
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        item: #729 of 7819
          id: cord-255247-9mvbcyjg
      author: Nelson, Caleb P.
       title: Timing and outcomes of testicular torsion during the COVID-19 crisis
        date: 2020-10-21
       words: 3102
      flesch: 45
     summary: The number of torsion case presentations per week to our facility increased from 0.7 cases/week in the pre-COVID-19 period to 1.3 cases/week during COVID-19 (p=0.015); when comparing only the March 1 to May 31 calendar period, there were 0.6 cases/week during the pre-COVID-19 period and 1.3 cases/week during COVID-19 (p=0.021). If there were significant numbers of torsion patients simply staying home, then we might expect that the number of torsion cases presenting to our facility would decrease.
    keywords: covid-19; patients; period; testicular; time; torsion
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        item: #730 of 7819
          id: cord-255294-x0ezeaz6
      author: Cilia, Roberto
       title: Effects of COVID‐19 on Parkinson's disease clinical features: a community‐based case‐control study
        date: 2020-05-25
       words: 2470
      flesch: 34
     summary: The main limitation of this study is the small cohort of COVID-19 patients, albeit statistical analysis could detect several significant changes. First, PD patients who develop symptomatic COVID-19 were neither older age nor with longer disease duration than those screening negative, but rather had nonsignificant 3.5-year younger age and 2.0-year shorter disease duration.
    keywords: cases; covid-19; disease; motor; patients; symptoms
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        item: #731 of 7819
          id: cord-255326-ito3q8da
      author: YOUMNI, A.
       title: Exploring Causal relationship between risk factors and vulnerability to COVID-19Cases of Italy, Spain, France, Greece, Portugal, Morocco and South Africa
        date: 2020-06-26
       words: 3909
      flesch: 54
     summary: The outcome was in-hospital confirmed infected COVID-19 cases as well as death among people with confirmed COVID-19, Covariates: Potential risk factors included: Age, body mass index (BMI; kg/m2, Diabetes prevalence, International arrivals, Population Density and median temperature in March and May. Furthermore, the rate of total infected cases is extremely different from one country to another as well as for the rate of mortality.
    keywords: cases; countries; covid-19; license; preprint; total
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        item: #732 of 7819
          id: cord-255360-yjn24sja
      author: O'Connor, Daryl B.
       title: Research priorities for the COVID‐19 pandemic and beyond: A call to action for psychological science
        date: 2020-07-19
       words: 11221
      flesch: 36
     summary: Concerns about mental health effects may be particularly heightened for children, who have experienced high levels of disruption to normative developmental opportunities (including opportunities for social and outdoor play) and education, and potentially high levels of family stress (https://emergingminds.org.uk/cospace-study-2ndupdate/). information brief COVID-19 impacts: School shutdown Severe acute respiratory syndrome (SARS) in Hong Kong in 2003: Stress and the psychological impact among frontline healthcare workers Psychosocial safety climate as a factor in organisational resilience: Implications for worker psychological health, resilience, and engagement Distress, worry, and functioning following a global health crisis: A national study of Americans' responses to Ebola Work-home interference: How does it manifest itself from day to day?
    keywords: behaviour; change; children; covid-19; covid-19 pandemic; effects; health; impact; need; outcomes; pandemic; people; priorities; psychological; research; science; social; stress; support; work
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        item: #733 of 7819
          id: cord-255364-slvcfj80
      author: Tuty Kuswardhani, R.A.
       title: Charlson comorbidity index and a composite of poor outcomes in COVID-19 patients: A systematic review and meta-analysis
        date: 2020-10-28
       words: 3185
      flesch: 41
     summary: The inclusion criteria of this study were studies of COVID-19 patients that reported any of the following: (1) odds ratios (ORs) and hazard ratios (HRs) of CCI score with a composite of poor outcomes (2) Mean CCI score for a composite of poor outcomes vs. no outcome, (3) per point HRs or ORs of CCI score and mortality. key: cord-255364-slvcfj80 authors: Tuty Kuswardhani, R.A.; Henrina, Joshua; Pranata, Raymond; Anthonius Lim, Michael; Lawrensia, Sherly; Suastika, Ketut title: Charlson comorbidity index and a composite of poor outcomes in COVID-19 patients: A systematic review and meta-analysis date: 2020-10-28 journal: Diabetes Metab Syndr DOI: 10.1016/j.dsx.2020.10.022 sha: doc_id: 255364 cord_uid: slvcfj80 BACKGROUND AND AIMS:
    keywords: cci; composite; covid-19; mortality; outcomes; patients; score
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        item: #734 of 7819
          id: cord-255365-fog62qdu
      author: Goldstein, Neal D.
       title: On the importance of early testing even when imperfect in a pandemic such as COVID-19
        date: 2020-08-03
       words: 1483
      flesch: 40
     summary: ScholarBank@NUS Repository CDC Has Fixed Issue Delaying Coronavirus Testing In U.S., Health Officials Say Dark gray corresponds to false negative test results assuming sensitivity between 60 and 100%, light gray corresponds to false positive test results assuming specificity between 90 and 100%, and the line is the true count of cases COVID-19) > One could also consider period prevalence of test results since the pandemic's inception.
    keywords: covid-19; prevalence; results; testing
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        item: #735 of 7819
          id: cord-255367-do9jw51z
      author: Fan, Qianqian
       title: Spontaneous pneumothorax and subpleural bullae in a patient with COVID-19: a 92-day observation
        date: 2020-09-21
       words: 900
      flesch: 41
     summary: It indicated subpleural consolidation with a persistent cough might be a risk factor of spontaneous pneumothorax and subpleural bullae in COVID-19 patients. key: cord-255367-do9jw51z authors: Fan, Qianqian; Pan, Feng; Yang, Lian title: Spontaneous pneumothorax and subpleural bullae in a patient with COVID-19: a 92-day observation date: 2020-09-21 journal: Eur J Cardiothorac Surg DOI: 10.1093/ejcts/ezaa305 sha: doc_id: 255367 cord_uid: do9jw51z
    keywords: covid-19; day; pneumothorax
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        item: #736 of 7819
          id: cord-255376-nqq5ieyg
      author: Safdar, Muhammad
       title: COVID‐19: A threat to educated Muslim women's negotiated identity in Pakistan
        date: 2020-05-08
       words: 7042
      flesch: 40
     summary: Zubair and Zubair (2017) argue through personal narratives of their research participants (Muslim women educated in English literature in Pakistan) that multiple positionalities and identities, like the one seen in Nisa, enable women to negotiate in the third space by being resistive to the local religioculturally defined patriarchal structures and the western concepts of women's autonomy. Through semi‐structured interviews, making an in‐depth comparative study of three differently situated cases (Muslim women), this study argues that the abnormal situation that has ensued from the pandemic has reinforced the vulnerability of women's nascent negotiated identity by landing them in a space where they are supposed by the normative structures to step back to carrying out their traditional responsibilities as ‘good’ wife and mother during the crisis.
    keywords: covid-19; gender; husband; identity; muslim; nisa; pakistan; pandemic; state; study; women
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        item: #737 of 7819
          id: cord-255381-mnmliv4e
      author: Peng, Min
       title: Prevalence, risk factors and clinical correlates of depression in quarantined population during the COVID-19 outbreak
        date: 2020-07-02
       words: 3396
      flesch: 39
     summary: Recent studies have shown that during the COVID-19 outbreak, the depression rate in the general population ranges from 3.7-48.3% (Ahmed et al., 2020; Gao et al., 2020; Lei et al., 2020; Tan et al., 2020; C. Wang et al., 2020; Wang, Di, Ye, & Wei, 2020; , and 6.46-50.7% among medical workers in China (Chen, Zhou, Zhou, & Zhou, 2020; Chew et al., 2020; S. Liu et al., 2020b; Shen et al., 2020; . The prevalence of depressive symptoms is high during the COVID-19 pandemic (Ahmed et al., 2020; Chen et al., 2020; Gao et al., 2020; Lei et al., 2020; S. Liu et al., 2020a; C. Wang et al., 2020; .
    keywords: covid-19; depression; et al; population; prevalence; quality; study; symptoms
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        item: #738 of 7819
          id: cord-255389-2fufd0ba
      author: Razonable, Raymund R.
       title: Mayo Clinic Strategies for COVID-19 Clinical Guidance and the Delivery of Care for Patients With Coronavirus Disease 2019
        date: 2020-06-23
       words: 1024
      flesch: 30
     summary: This clinical team rapidly developed expertise in COVID-19 care because they served as consultants to frontline health care providers. 2, 3 In the process, our medical providers took ownership and implemented the guidance recommendations, which encompassed various aspects of COVID-19 medical care from the time of disease diagnosis until patient recovery.
    keywords: care; covid-19; guidance
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        item: #739 of 7819
          id: cord-255405-o8ilxqo1
      author: Sharma, V. K.
       title: Modelling of Covid-19 cases in India using Regression and Time Series models
        date: 2020-05-25
       words: 4023
      flesch: 60
     summary: [19] for more details on ARIMA model, estimation and its application ARIMA is a joint model of two models, autoregressive AR p and moving average MA q and is integrated using the difference variable, d. The AIC, CAIC and BIC are given by where K=number of model parameters, and N=no. of data points.
    keywords: arima; cases; covid-19; exponential; growth; india; model
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        item: #740 of 7819
          id: cord-255435-mr239gai
      author: Sher, Yelizaveta
       title: A CASE REPORT OF COVID-19 ASSOCIATED HYPERACTIVE ICU DELIRIUM WITH PROPOSED PATHOPHYSIOLOGY AND TREATMENT
        date: 2020-05-19
       words: 3529
      flesch: 31
     summary: While no studies have demonstrated pharmacological efficacy in the management of delirium among COVID-19 patients, we provide a framework for choosing psychotropic medications to assist in achieving behavioral control in ICU patients. Delirium, which is highly prevalent in general intensive care unit (ICU) populations, is expected to be frequent and prominent in COVID-19 patients hospitalized with acute respiratory distress syndrome (ARDS) in ICU.
    keywords: case; covid-19; day; delirium; icu; management; patients; treatment
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        item: #741 of 7819
          id: cord-255440-ls1l2mlg
      author: Tindle, Courtney
       title: Adult Stem Cell-derived Complete Lung Organoid Models Emulate Lung Disease in COVID-19
        date: 2020-10-18
       words: 9984
      flesch: 41
     summary: Organoids and monolayers used for lung cell type studies were lysed using RNA lysis buffer followed by RNA CoV2 studies were lysed in TRI-Reagent and RNA was extracted using Zymo Research Direct-zol RNA Miniprep. Organoid and monolayer cell-type gene expression was measured by qRT-PCR using 2x SYBR Green qPCR Master Mix. As for personalization, our model is derived from adult lung stem cells from deep lung biopsies; each organoid line was established from one patient.
    keywords: airway; ali; alveolar; at2; cells; cov-2; covid-19; epithelial; et al; expression; fig; gene; host; human; lung; media; model; monolayers; organoids; pneumocytes; response; rna; sars; signatures; type
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        item: #742 of 7819
          id: cord-255457-jlbg8jdv
      author: Li, Jiawei
       title: Application of CareDose 4D combined with Karl 3D technology in the low dose computed tomography for the follow-up of COVID-19
        date: 2020-05-24
       words: 2912
      flesch: 57
     summary: Although there was no significant difference in CT signs and image quality between the study group and control group, the differences in CTDIvol, DLP, and ED between the two groups were statistically significant (t = 31.14, 27.73, 27.73, p < 0.01, Table 4 ). Exclusion criteria: ① patients with underlying lung diseases, such as lung tumors, tuberculosis, and other infections in the lungs; ② patients could not cooperate for some reason, which led to blurred CT images.
    keywords: control; covid-19; dose; group; image; study
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        item: #743 of 7819
          id: cord-255461-i5kw4z5g
      author: D'Marco, Luis
       title: Diabetic Kidney Disease and COVID-19: The Crash of Two Pandemics
        date: 2020-05-06
       words: 1001
      flesch: 36
     summary: At present, the main expression of renal damage in COVID-19 patients appear to be acute; however, some cases of macroalbuminuria/proteinuria and or haematuria may be associated with the endothelial dysfunction observed in these patients (Figure 1 ) (16) . Diabetic kidney disease (DKD) is a major cause of morbidity and mortality in diabetes and estimations report that ∼30-40% of DM patients will develop DKD.
    keywords: covid-19; disease; patients
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        item: #744 of 7819
          id: cord-255466-g3b283ym
      author: Bhagra, Ojas
       title: An Integrated and Intergenerational Community Response to Promote Holistic Wellbeing During the COVID-19 Pandemic
        date: 2020-07-02
       words: 1792
      flesch: 38
     summary: In addition to HCWs needing community support to relieve the strain of massive patient influxes, pandemics take immense tolls on the mental, emotional, and holistic wellbeing of communities through the lack of connectivity due to isolation, social distancing, and cancellations of major social and life events 5 . Furthermore, participating in a meaningful part of the pandemic response gives a sense of unity for community members in a time where isolation and lack of control increase the chances to feel helpless or insignificant.
    keywords: community; hcws; health; pandemic
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        item: #745 of 7819
          id: cord-255473-kizyv6mp
      author: Ferrari, D.
       title: Machine learning in predicting respiratory failure in patients with COVID-19 pneumonia - challenges, strengths, and opportunities in a global health emergency
        date: 2020-06-02
       words: 3421
      flesch: 41
     summary: This analysis aimed to determine a 48 hours prediction of moderate to severe respiratory failure, as assessed with PaO2/FiO2 < 150 mmHg, in hospitalized patients with COVID-19 pneumonia. The study outcome was the onset of moderate to severe respiratory failure defined as PaO2/FiO2 ratio < 150 mmHg ([≥] 13.3 kPa) in at least one of two consecutive arterial blood gas analyses in the following 48 hours.
    keywords: covid-19; failure; license; medrxiv; model; patients; preprint
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        item: #746 of 7819
          id: cord-255474-7fq9culd
      author: Alifano, Marco
       title: Renin-angiotensin system at the heart of COVID-19 pandemic
        date: 2020-04-16
       words: 2603
      flesch: 31
     summary: We decided to use the analogy of a play and speculate about the possible impact in this tragedy of 1) air pollution via the interference of nitrogen dioxide on ACE2 expression; 2) the dual role of nicotine; 3) the hypothetical involvement of ACE2 polymorphisms, the relationships of which with ethnic factors and susceptibility to cardiovascular disease seems intriguing; 4) the impact on the severity of infection of hypertension and related medications acting on the renin/angiotensin system, and, finally, 5) the possible helpful role of chloroquine, thanks to its capacity of modifying ACE2 affinity to the viral spike protein by altering glycosylation. ACE2 polymorphisms: imbrication with associated illness and possible different susceptibility to infection.
    keywords: ace2; angiotensin; covid-19; hypertension; receptor; sars; system
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        item: #747 of 7819
          id: cord-255476-p0gyyl3c
      author: Hsu, Albert L.
       title: Placental SARS‐CoV‐2 in a Pregnant Woman with Mild COVID‐19 Disease
        date: 2020-08-04
       words: 3315
      flesch: 47
     summary: Clinical Characteristics of 46 Pregnant Women with a SARS-CoV-2 Infection in Washington State Coronavirus disease 2019 among pregnant Chinese women: case series data on the safety of vaginal birth and breastfeeding BJOG Neonatal Late Onset Infection with Severe Acute Respiratory Syndrome Coronavirus 2 Coronavirus disease 2019 in pregnancy Coronavirus disease 2019 (COVID-19) in pregnant women: A report based on 116 cases Public Health Agency of Sweden's brief report: pregnant and postpartum women with SARS-CoV-2 infection in intensive care in Sweden Has Sweden's controversial covid-19 strategy been successful? Vertical transmission of COVID-19: SARS-CoV-2 RNA on the fetal side of the placenta in pregnancies with COVID-19 positive mothers and neonates at birth Detection of SARS-COV-2 in Placental and Fetal Membrane Samples Second-Trimester Miscarriage in a Pregnant Woman With SARS-CoV-2 Infection SARS-CoV-2 infection of the placenta Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Report of Positive Placental Swabs for SARS-CoV-2 in an Asymptomatic Pregnant Woman with COVID-19 Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn COVID-19 and its implications for thrombosis and anticoagulation Placental Pathology in Covid-19 positive mothers: Preliminary Findings Placental Pathology in Covid-19 Fetal vascular malperfusion If You Are Pregnant, Breastfeeding, or Caring for Young Children Late miscarriage as a presenting manifestation of COVID-19 Change in the Incidence of Stillbirth and Preterm Delivery During the COVID-19 Perinatal Transmission of COVID-19 Associated SARS-CoV-2: Should We Worry? Detection of SARS-CoV-2 in human breastmilk The Lancet Coronavirus disease 2019 among pregnant Chinese women: case series data on the safety of vaginal birth and breastfeeding BJOG Vaginal delivery in SARS-CoV-2-infected pregnant women in Northern Italy: a retrospective analysis BJOG This article is protected by copyright. The inexorable rise in COVID-19 cases in the United States amid decreasing adherence to public health recommendations raises concern for the possibility of viral mutations.
    keywords: cov-2; covid-19; disease; placental; pregnancy; sars; women
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        item: #748 of 7819
          id: cord-255492-50vo8bnc
      author: Thureau, Sébastien
       title: Adapting palliative radiation therapy for bone metastases during the Covid-19 pandemic: GEMO position paper
        date: 2020-04-13
       words: 1795
      flesch: 38
     summary: key: cord-255492-50vo8bnc authors: Thureau, Sébastien; Faivre, Jean Christophe; Assaker, Richard; Biver, Emmanuel; Confavreux, Cyrille B.; Debiais, Françoise; Duterque-Coquillaud, Martine; Giammarile, Fransesco; Heymann, Dominique; Lecouvet, Frédéric E.; Morardet, Laetitia; Paycha, Frederic; Body, Jean-Jacques; Vieillard, Marie-Hélène title: Adapting palliative radiation therapy for bone metastases during the Covid-19 pandemic: GEMO position paper date: 2020-04-13 journal: J Bone Oncol DOI: 10.1016/j.jbo.2020.100291 sha: doc_id: 255492 cord_uid: 50vo8bnc This is particularly the case for radiotherapy of bone metastases for which it is possible to reduce the number of sessions, the frequency of transport and the complexity of treatments.
    keywords: bone; metastases; radiotherapy; treatment
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        item: #749 of 7819
          id: cord-255495-xnoppq3y
      author: Elrashdy, Fatma
       title: On the potential role of exosomes in the COVID-19 reinfection/reactivation opportunity
        date: 2020-07-09
       words: 7538
      flesch: 35
     summary: Disaster Medicine and Public Health Preparedness MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-a treatment Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn Eleven faces of coronavirus disease Ultrastructural evidence for direct renal infection with SARS-CoV-2 Vaginal delivery in SARS-CoV-2 infected pregnant women in Northern Italy: A retrospective analysis Spread and dynamics of the COVID-19 epidemic in Italy: Effects of emergency containment measures The role of extracellular vesicles as allies of HIV, HCV and SARS viruses Expanding our understanding of the role polyprotein conformation plays in the coronavirus life cycle Modern uses of electron microscopy for detection of viruses Ultrastructural characterization of SARS coronavirus Pathology and pathogenesis of severe acute respiratory syndrome Respiratory viral infection in lung transplantation induces exosomes that trigger chronic rejection Donorderived exosomes with lung self-antigens in human lung allograft rejection The role of extracellular vesicles in COVID-19 virus infection Recurrence of positive SARS-CoV-2 in patients recovered from COVID-19 Retest positive for SARS-CoV-2 RNA of recovered patients with COVID-19: A very interesting case was recently reported, where a 78-year-old woman that was ready to be discharged after the three consecutive PCR tests on her nasopharyngeal swab samples indicated that she was SARS-CoV-2 negative, her conditions were significantly improved, and CT examination showed absorption of pulmonary exudation, but suddenly she fell into the cardiac arrest and died (Yao et al., 2020) .
    keywords: cells; coronavirus; cov-2; covid-19; dmvs; et al; infection; membrane; particles; patients; pcr; replication; rna; sars; vesicles; virus
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        item: #750 of 7819
          id: cord-255513-h8v6hba4
      author: Atar, Shaul
       title: An Invited Commentary on “The Socio-Economic Implications of the Coronavirus and COVID-19 Pandemic: A Review”
        date: 2020-04-29
       words: 552
      flesch: 44
     summary: These delays may be explained by the fear of patients from attending the emergency room and possible exposure to infected patients and also by the time it takes for physicians to properly protect themselves when treating suspected or confirmed patients. The anxiety and fear of infection causes a significant delay in seeking medical care due to other unrelated medical conditions -both acute and chronic.
    keywords: covid-19; pandemic
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        item: #751 of 7819
          id: cord-255525-7w5u789h
      author: de Sales, Anderson Ribeiro
       title: The Reversed Halo Sign and COVID-19: Possible Histopathological Mechanisms Related to the Appearance of this Imaging Finding
        date: 2020-07-27
       words: 1001
      flesch: 34
     summary: Consistently, histopathological examination of a transthoracic-needle lung biopsy sample from a patient who died 3 weeks after COVID-19 diagnosis showed diffuse alveolar damage in the organizing phase, with intra-alveolar fibrinous exudates, interstitial fibrosis, intraalveolar fibrous plugs and organizing fibrin at most foci. The predominant CT findings of COVID-19 pneumonia are multifocal, bilateral, peripheral, and basal-predominant ground-glass opacities, often with round and/or oval morphology and/or consolidation.
    keywords: covid-19; organizing; rhs
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        item: #752 of 7819
          id: cord-255572-tbrdis86
      author: Norton, Alice
       title: Baseline results of a living systematic review for COVID-19 funded research projects
        date: 2020-09-08
       words: 8743
      flesch: 40
     summary: The lack of alignment of funded research projects to the 'Ethics considerations for research' priority may be one such example, as it misses the direct activity that the WHO has undertaken in to address this priority through direct research and provision of important guidance on ethical matters relating to COVID-19 11 which align to the sub-priorities as well as the clear strength of ethical consideration across the majority of research projects (which don't have a core focus on ethics). There is however a need for greater coordination, with limited resources and the shifting global nature of the pandemic resulting in a proliferation of research projects underpowered and unable to achieve their aims.
    keywords: areas; covid-19; data; funders; funding; health; priorities; priority; projects; research; research projects; sub; tracker
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        item: #753 of 7819
          id: cord-255586-wshvvgxg
      author: He, Shengyang
       title: Clinical characteristics of “re-positive” discharged COVID-19 pneumonia patients in Wuhan, China
        date: 2020-10-15
       words: 2923
      flesch: 38
     summary: Re-positive patients could not be distinguished by demographic features, clinical symptoms, laboratory results, comorbidities, co-infections, treatments, Common clinical characteristics were not able to distinguish re-positive patients.
    keywords: cov-2; covid-19; laboratory; patients; results; sars; study; symptoms
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        item: #754 of 7819
          id: cord-255600-2xs29l81
      author: Nazroo, J.
       title: Evidence for ethnic inequalities in mortality related to COVID-19 infections: Findings from an ecological analysis of England and Wales
        date: 2020-06-09
       words: 3908
      flesch: 39
     summary: This coefficient shows that for every 1% rise in proportion of the population who are ethnic minority COVID-19 related deaths increased by 5·10 (3·99 to 6·21) per million. The size of this increase is a little reduced in a fully adjusted model, suggesting that some of the association results from ethnic minority people living in more densely populated, more polluted and more deprived areas.
    keywords: covid-19; ethnic; inequalities; minority; people; population
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        item: #755 of 7819
          id: cord-255602-3pzh5ur9
      author: Moscadelli, Andrea
       title: Fake News and Covid-19 in Italy: Results of a Quantitative Observational Study
        date: 2020-08-12
       words: 4595
      flesch: 47
     summary: Links that contained fake news were shared 2,352,585 times, accounting for 23.1% of the total shares of all the articles reviewed. In order to understand the reason for the success of fake news in such situations, it is necessary to analyze the impact of the quarantine on the Italian population and the psychological strain that it caused.
    keywords: articles; covid-19; fake; health; media; news; pandemic; shares
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        item: #756 of 7819
          id: cord-255603-quuju9h4
      author: Kumar, Aishwarya
       title: A review of modern technologies for tackling COVID-19 pandemic
        date: 2020-05-07
       words: 3302
      flesch: 42
     summary: COVID-Net an artificial intelligence application is created to analyze COVID-19 symptoms in chest x-rays utilizing information of different lung conditions and COVID-19 from patients [10] . In a diagnostic study, an AI platform was established using inception migration neural network for extracting COVID-19 symptoms using CT images, achieving 89.5% accuracy
    keywords: coronavirus; covid-19; disease; information; learning; model; patients; technology
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        item: #757 of 7819
          id: cord-255604-hnbzidf3
      author: Liu, Liping
       title: Approaches to global stroke care during the COVID-19 pandemic
        date: 2020-05-23
       words: 1265
      flesch: 54
     summary: 4 5 Realising this challenge and urgency, the Chinese Stroke Association convened a group of international stroke leaders and discussed the challenges facing stroke care worldwide and recommendations of stroke care during the COVID-19 pandemic. 6 COVID-19 will thus likely change our way of delivering stroke care for years to come.
    keywords: care; covid-19; patients; stroke
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        item: #758 of 7819
          id: cord-255625-4r6ng57a
      author: Graffigna, Guendalina
       title: “Cultivating” acceptance of a COVID-19 vaccination program: Lessons from Italy
        date: 2020-11-10
       words: 631
      flesch: 41
     summary: Results of our study showed that 41% of the participants reported to be unwilling or hesitant towards COVID-19 vaccine. Citizens need to be engaged in a deep process of psychological acceptance, in order to adopt a socially responsible approach to COVID-19 preventive behaviors [4, 5] .
    keywords: covid-19; vaccine
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        item: #759 of 7819
          id: cord-255631-516epnjw
      author: Syeda, H. B.
       title: The Role of Machine Learning Techniques to Tackle COVID-19 Crisis: A Systematic Review.
        date: 2020-08-25
       words: 6760
      flesch: 40
     summary: the preprint server for health sciences Modified SEIR and AI prediction of the epidemics trend of COVID-19 in China under public health interventions Predicting COVID-19 in China Using Hybrid AI Model Modelling-based evaluation of the effect of quarantine control by the Chinese government in the coronavirus disease 2019 outbreak. https://doi.org/10.1101/2020.08.23.20180158 doi: medRxiv preprint ML methods and identified 3 themes: models developed to address issues central to Epidemiology; models that aid the diagnosis of patients with COVID-19; and models that help prognosis of COVID-19 patients.
    keywords: chest; coronavirus; covid-19; data; disease; health; learning; license; medrxiv; patients; perpetuity; preprint; preprint server; review; studies; study
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        item: #760 of 7819
          id: cord-255665-srvz2ay0
      author: Ferrari, Marco
       title: COVID-19 screening protocols for preoperative assessment of head and neck cancer patients candidate for elective surgery in the midst of the pandemic: a narrative review with comparison between two Italian institutions
        date: 2020-10-14
       words: 2488
      flesch: 35
     summary: The ideal management of COVID-19 patients has been improved and standardized by various reports dealing with risk-stratification, therapy, and follow-up. To date, there is no clear-cut indication that blood chemistry can serve as a screening The role of CT in first-line diagnosis and screening of COVID-19 patients is a muchdebated topic.
    keywords: cov-2; covid-19; patients; sars; screening; surgery
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        item: #761 of 7819
          id: cord-255669-gpc5k7lf
      author: de Burgos-Berdud, Isabel
       title: Are healthcare workers during the COVID-19 pandemic at risk of psychosis? Findings from a scoping review
        date: 2020-07-02
       words: 145
      flesch: 7
     summary: Psychological distress, coping behaviors, and preferences for support among New York healthcare workers during the COVID-19 pandemic Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis Brief Psychotic Disorder Triggered by Fear of Coronavirus? Reactive psychoses in the context of the COVID-19 pandemic: Clinical perspectives from a case series Unravelling potential severe psychiatric repercussions on healthcare professionals during the COVID-19 crisis Psychological Support System for Hospital Workers During the Covid-19 Outbreak: Rapid Design and Implementation of the Covid-Psy Hotline None. key: cord-255669-gpc5k7lf authors: de Burgos-Berdud, Isabel; Valdés-Florido, María José; López-Díaz, Álvaro title: Are healthcare workers during the COVID-19 pandemic at risk of psychosis?
    keywords: covid-19
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        item: #762 of 7819
          id: cord-255694-cdpsy36f
      author: Dobler, Claudia C.
       title: Poor quality research and clinical practice during COVID-19
        date: 2020-06-17
       words: 1204
      flesch: 41
     summary: on how #COVID19 amplifies flaws in clinical research and practice https://bit.ly/3cX0jpO The COVID-19 pandemic has turned our lives upside down. COVID-19, however, also highlights and amplifies some of the challenges clinical research and practice are facing in general.
    keywords: covid-19; patients; practice; research
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        item: #763 of 7819
          id: cord-255695-10stetqg
      author: Riad, Abanoub
       title: Oral Candidiasis in Non‐Severe COVID‐19 Patients: Call for Antibiotic Stewardship
        date: 2020-09-21
       words: 771
      flesch: 28
     summary: Therefore, we aim to describe a non‐severe COVID‐19 case with oral candidiasis according to the CARE guidelines.(3) Dear Editor, Bacterial/fungal coinfection is a suggested etiological theory for the COVID-19 related oral manifestations that may trigger overprescribing of broad-spectrum antibiotics for COVID-19 patients, especially for the ones who experience a longer course of the infection. Oral Dis Oropharyngeal candidiasis in hospitalised COVID-19 patients from Iran: Species identification and antifungal susceptibility pattern The CARE guidelines: Consensus-based clinical case reporting guideline development Bacterial and fungal co-infection in individuals with coronavirus: A rapid review to support COVID-19 antimicrobial prescribing The impact of coronavirus infectious disease 19 (COVID-19) on oral health Accepted Article
    keywords: antibiotics; candidiasis; covid-19
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        item: #764 of 7819
          id: cord-255719-vhjmkrlb
      author: Manghat, Nathan E.
       title: Acute Post-operative Thrombosis of an Aortic Valve Prosthesis and Embolic Myocardial Infarction in a COVID-positive patient - An Unrecognised Complication
        date: 2020-09-23
       words: 444
      flesch: 20
     summary: key: cord-255719-vhjmkrlb authors: Manghat, Nathan E.; Hamilton, Mark C.K.; Joshi, Nikhil V.; Vohra, Hunaid A. title: Acute Post-operative Thrombosis of an Aortic Valve Prosthesis and Embolic Myocardial Infarction in a COVID-positive patient - An Unrecognised Complication date: 2020-09-23 journal: JTCVS Tech DOI: 10.1016/j.xjtc.2020.09.020 sha: doc_id: 255719 cord_uid: vhjmkrlb A 73 year old female patient presented 14 days post aortic valve replacement (AVR) for bicuspid valve stenosis; she was diagnosed with COVID-19 infection, acute myocardial infarction, pulmonary embolism and retinal artery embolism. A 73 year old female patient presented 14 days post aortic valve replacement (AVR) for bicuspid valve stenosis; she was diagnosed with COVID-19 infection, acute myocardial infarction, pulmonary embolism and retinal artery embolism.
    keywords: covid-19; valve
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        item: #765 of 7819
          id: cord-255746-ir73lpi8
      author: Sirimaturos, Michael
       title: Clinical Outcomes Following Tocilizumab Administration in Mechanically Ventilated Coronavirus Disease 2019 Patients
        date: 2020-10-01
       words: 4106
      flesch: 32
     summary: While several reports on tocilizumab treatment in COVID-19 patients now exist, data pertaining specifically to tocilizumab use in a large cohort of critically ill patients on invasive ventilation is lacking (11, 12) . This retrospective review of COVID-19 patients managed within the Houston Methodist Hospital System from March 24, 2020, to May 4, 2020, used data from electronic medical records and the institution's clinical surveillance program.
    keywords: administration; covid-19; days; disease; improvement; mortality; patients; tocilizumab; treatment
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        item: #766 of 7819
          id: cord-255752-ofph98ac
      author: Chegondi, Madhuradhar
       title: Coronavirus Disease 2019 (COVID-19) Associated With Febrile Status Epilepticus in a Child
        date: 2020-08-18
       words: 1618
      flesch: 52
     summary: In the United States, 1.7% of all confirmed COVID-19 cases are children (≤18 years), and 5%-20% of them were hospitalized [4] . Neurological involvement in COVID-19 patients has been described.
    keywords: children; coronavirus; covid-19; hcov; seizures
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        item: #767 of 7819
          id: cord-255817-asdjlq07
      author: Ozaras, Resat
       title: An open call for influenza vaccination pending the new wave of COVID‐19
        date: 2020-07-14
       words: 527
      flesch: 45
     summary: 3 The epidemiology and clinical characteristics of co-infection of SARS-CoV-2 and influenza viruses in patients during COVID-19 outbreak Influenza and COVID-19 coinfection: report of 6 cases and review of the literature Clinical characteristics of critically ill patients co-infected with SARS-CoV-2 and the influenza virus in Wuhan, China Co-infection with respiratory pathogens among COVID-2019 cases Co-infection in SARS-CoV-2 infected patients: where are influenza virus and rhinovirus/enterovirus? Rates of co-infection between SARS-CoV-2 and other respiratory pathogens Epidemiological evidence for association between higher influenza vaccine uptake in the elderly and lower COVID-19 deaths in Italy The possible beneficial adjuvant effect of influenza vaccine to minimize the severity of COVID-19. A recent research found moderate to strong correlation between higher influenza vaccine uptake in the elderly and lower COVID-19 deaths in Italy.
    keywords: covid-19; influenza
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        item: #768 of 7819
          id: cord-255867-moriv0va
      author: Sheth, Parth D.
       title: Development of a Surgical Workforce Access Team (SWAT) in the Battle Against COVID-19
        date: 2020-04-30
       words: 1391
      flesch: 45
     summary: Providers in surgical fields, especially residents, 1 have likewise been redeployed to ICUs and medicine teams. Advanced practice providers have 2 been shifted to the emergency department, testing centers, and call center teams triaging 3 COVID-19 patients.
    keywords: covid-19; patients; team; vein
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        item: #769 of 7819
          id: cord-255883-mz6nyisw
      author: Asif, Muhammad
       title: COVID-19 and therapy with essential oils having antiviral, anti-inflammatory, and immunomodulatory properties
        date: 2020-08-14
       words: 5302
      flesch: 35
     summary: After the emergence of shreds of preliminary scientific evidences about anti-SARC-CoV-2 potentials of essential oils and their active components, various essential oils selling and extraction companies claimed about efficacy of their essential oils bearing products against COVID-19. MicrobiologyOpen 6:e00459 Safety of essential oils Relaxant effects of the essential oil of Eucalyptus tereticornis and its main constituent 1,8-cineole on guinea-pig tracheal smooth muscle Menthol: effects on nasal sensation of airflow and the drive to breathe SARS-CoV-2 RNA dependent RNA polymerase (RdRp) targeting: an in silico perspective Structurally related monoterpenes p-cymene, carvacrol and thymol isolated from essential oil from leaves of Lippia sidoides Cham.
    keywords: cells; cov-2; covid-19; effects; eos; et al; eucalyptus; oils; sarc; sars; study; virus
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        item: #770 of 7819
          id: cord-255884-0qqg10y4
      author: Chiroma, H.
       title: Early survey with bibliometric analysis on machine learning approaches in controlling coronavirus
        date: 2020-11-05
       words: 13211
      flesch: 43
     summary: Ahuja et al. (2020) reported that COVID-19 data are now growing. In this section, we present the sources of COVID-19 data to the machine learning community.
    keywords: analysis; author; chest; cnn; coronavirus; covid-19; data; deep; et al; images; learning; license; machine; machine learning; medrxiv; model; pandemic; patients; preprint; research; study
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        item: #771 of 7819
          id: cord-255899-ehcod7c4
      author: Urano, Akira
       title: Short-Term Corticosteroid Therapy for Early Exacerbation of COVID-19 Pneumonia: A Case Report
        date: 2020-08-14
       words: 1518
      flesch: 35
     summary: Furthermore, corticosteroid treatment is not currently recommended for COVID-19 patients [10] . However, it remains unclear which COVID-19 patients benefit from corticosteroid treatment.
    keywords: corticosteroid; covid-19; pneumonia; treatment
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        item: #772 of 7819
          id: cord-255908-gcttlpxm
      author: Kiprov, Dobri
       title: Immunomodulation for the Management of Corona Virus Disease (COVID-19)
        date: 2020-06-27
       words: 592
      flesch: 41
     summary: Deployment of convalescent plasma for the prevention and treatment of COVID-19 Covid-19 and Immunity in Aging Populations -A New Research Agenda A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood Intermittent Heterochronic Plasma Exchange as a Modality for Delaying Cellular Senescence -A Hypothesis A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19 Immune or convalescent plasma collected from people who have fully recovered from infection contains antibodies against the infectious agent.
    keywords: covid-19; plasma
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        item: #773 of 7819
          id: cord-255909-m94j1rh4
      author: Shree, Priya
       title: Targeting COVID-19 (SARS-CoV-2) main protease through active phytochemicals of ayurvedic medicinal plants – Withania somnifera (Ashwagandha), Tinospora cordifolia (Giloy) and Ocimum sanctum (Tulsi) – a molecular docking study
        date: 2020-08-27
       words: 5501
      flesch: 36
     summary: Most of biological action contributed by Withaferin-A and Withanolide D, along with Withanoside I-VII, new Withanolide Glycosides, extracted from its roots (Matsuda et al., 2001) . Withanoside V is a glycoside obtained from W. somnifera roots, reported to have tachyphylaxis inhibition activity (Matsuda et al., 2001) .
    keywords: binding; cordifolia; covid-19; kcal; mol; pro; protease; sars; somnifera; study
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        item: #774 of 7819
          id: cord-255940-chb4iuis
      author: Walton, David A.
       title: Facility-Level Approaches for COVID-19 When Caseload Surpasses Surge Capacity
        date: 2020-06-26
       words: 1802
      flesch: 37
     summary: 8, 9 Modeling by Cornell University and Oxford University projects up to 430,000 people in Haiti might require hospitalization, which would require more than 9,000 additional hospital beds 10 ; however, fewer than 300 hospital beds are currently available for COVID-19 patients. Haiti offers one example, but other countries have experienced similar challenges with vulnerable populations, often leveraging unique solutions to add additional bed capacity for COVID-19 patients.
    keywords: care; covid-19; health; patients; testing
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        item: #775 of 7819
          id: cord-255941-uc6z0vuu
      author: Desai, Mauli
       title: “The Importance of Considering Olfactory Dysfunction During the COVID-19 Pandemic and in Clinical Practice”
        date: 2020-10-28
       words: 1439
      flesch: 37
     summary: key: cord-255941-uc6z0vuu authors: Desai, Mauli; Oppenheimer, John title: “The Importance of Considering Olfactory Dysfunction During the COVID-19 Pandemic and in Clinical Practice” date: 2020-10-28 journal: J Allergy Clin Immunol Pract DOI: 10.1016/j.jaip.2020.10.036 sha: doc_id: 255941 cord_uid: uc6z0vuu The emergence of a worldwide pandemic due to coronavirus disease 2019 (COVID-19) and frequent reports of smell loss in COVID-19 infected patients has brought new attention to this very important sense. We will also focus on the emerging literature on COVID-19 olfactory dysfunction, its unique features, and its important implications for this pandemic.
    keywords: covid-19; patients; smell; taste
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        item: #776 of 7819
          id: cord-256008-lwki1rzc
      author: Sekeroglu, Boran
       title: Detection of COVID-19 from Chest X-Ray Images Using Convolutional Neural Networks
        date: 2020-09-18
       words: 6955
      flesch: 43
     summary: Furthermore, because of the use of a relatively small number of COVID-19 images, clinical information about the patients, such as risk factors and medical history, is not available at this time. Detection of COVID-19 from chest X-ray images is of vital importance for both doctors and patients to decrease the diagnostic time and reduce financial costs. A total of 34 experiments were performed in this category, 17 each of COVID-19/Normal and COVID-19/ Pneumonia, to evaluate and analyze the performance of ConvNets under different conditions to achieve an optimal classification of COVID-19 images.
    keywords: covid-19; experiments; images; learning; mean; normal; pneumonia; pre; results; roc
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        item: #777 of 7819
          id: cord-256011-0cr4ejxu
      author: de Castro-Hamoy, Leniza
       title: Age Matters but it should not be Used to Discriminate Against the Elderly in Allocating Scarce Resources in the Context of COVID-19
        date: 2020-06-16
       words: 4413
      flesch: 46
     summary: Elderly COVID-19 patients are among those who are worst off because they appear to be the most likely to succumb to the disease. Human beings-rather than human life years-are asking to be saved.
    keywords: age; allocation; care; covid-19; life; number; patient
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        item: #778 of 7819
          id: cord-256020-wrui3i2l
      author: Fadaka, Adewale Oluwaseun
       title: Understanding the epidemiology, pathophysiology, diagnosis and management of SARS-CoV-2
        date: 2020-08-26
       words: 7116
      flesch: 43
     summary: Certain classes of compounds, called surfactants, are contained in soap and have the ability to neutralize microbes such as SARS CoV-2. A pneumonia outbreak associated with a new coronavirus of probable bat origin Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China A novel coronavirus emerging in China-key questions for impact assessment Recent insights into the biology of pancreatic cancer Paracrine and cell autonomous signalling in pancreatic cancer progression and metastasis Current and emerging therapies for patients with advanced pancreatic ductal adenocarcinoma: a bright future SARS and other coronaviruses as causes of pneumonia Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient Potential maternal and infant outcomes from coronavirus 2019-nCoV (SARS-CoV-2) infecting pregnant women: Lessons from SARS, MERS, and other human coronavirus infections Subunit vaccines against emerging pathogenic human coronaviruses Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Viral and cellular mRNA translation in coronavirus-infected cells Molecular evolution of human coronavirus genomes From SARS to MERS, thrusting coronaviruses into the spotlight A complete sequence and comparative analysis of a SARS-associated virus (isolate BJ01) Ultrastructural characterization of SARS coronavirus The genome sequence of the SARS-associated coronavirus Asymptomatic cases in a family cluster with SARS-CoV-2 infection Bat origin of human coronaviruses Isolation and growth characterization of novel full length and deletion mutant human MERS-CoV strains from clinical specimens collected during Middle East Respiratory Syndrome: Emergence of a pathogenic human coronavirus Cryo-electron tomography of mouse hepatitis virus: insights into the structure of the coronavirion Supramolecular architecture of severe acute respiratory syndrome coronavirus revealed by electron cryomicroscopy The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex
    keywords: cases; cells; coronavirus; cov-2; covid-19; covs; disease; figure; human; infection; mers; novel; patients; protein; receptor; sars; symptoms
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        item: #779 of 7819
          id: cord-256041-k4y6t0i5
      author: Gómez-Salgado, Juan
       title: Related Health Factors of Psychological Distress During the COVID-19 Pandemic in Spain
        date: 2020-06-02
       words: 5962
      flesch: 45
     summary: Gen The Psychological Impact of the SARS Epidemic on Hospital Employees in China: Exposure, Risk Perception, and Altruistic Acceptance of Risk Predictive factors of psychological disorder development during recovery following SARS outbreak Factors influencing psychological distress during a disease epidemic: Data from Australia's first outbreak of equine influenza General hospital staff worries, perceived sufficiency of information and associated psychological distress during the A/H1N1 influenza pandemic Severe acute respiratory syndrome (SARS) in Hong Kong in 2003: Stress and psychological impact among frontline healthcare workers Psychological impact of the 2003 severe acute respiratory syndrome outbreak on health care workers in a medium size regional general hospital in Singapore Public perceptions, anxiety, and behaviour change in relation to the swine flu outbreak: Cross sectional telephone survey Demographic and attitudinal determinants of protective behaviours during a pandemic: A review Community Psychological and Behavioral Responses through the First Wave of the 2009 Influenza A(H1N1) Pandemic in Hong Kong Avoidance behaviors and negative psychological responses in the general population in the initial stage of the H1N1 pandemic in Hong Kong A Systematic Review of the Impact of Disaster on the Mental Health of Medical Responders Understanding, compliance and psychological impact of the SARS quarantine experience A Longitudinal Study on the Mental Health of General Population during the COVID-19 Epidemic in China The Impact of COVID-19 Epidemic Declaration on Psychological Consequences: A Study on Active Weibo Users A nationwide survey of psychological distress among Chinese people in the COVID-19 epidemic: Implications and policy recommendations The distress of Iranian adults during the Covid-19 pandemic-More distressed than the Chinese and with different predictors First study on mental distress in Brazil during the COVID-19 crisis A Nationwide Survey of Psychological Distress among Italian People during the COVID-19 Pandemic: Immediate Psychological Responses and Associated Factors Affective temperament, attachment style, and the psychological impact of the COVID-19 outbreak: An early report on the Italian general population Association of Self-perceptions of Aging, Personal and Family Resources The differential psychological distress of populations affected by the COVID-19 pandemic Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). In this study, various sociodemographic variables, variables related to the presence of physical symptoms, and other health-related ones have been identified as predictors of the presence of psychological distress symptoms among the Spanish population during a period of health alert due to the COVID-19 epidemic.
    keywords: contact; covid-19; distress; health; participants; people; study; symptoms; variables
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        item: #780 of 7819
          id: cord-256042-1yq7kf7d
      author: McDonnell, Sarah
       title: The impact of the Covid-19 pandemic on maternity services: a review of maternal and neonatal outcomes before, during and after the pandemic
        date: 2020-10-12
       words: 2914
      flesch: 43
     summary: Termination of pregnancies with chromosomal or congenital anomalies which may have been predisposed to either spontaneous or iatrogenic preterm delivery may in part contribute to the noted reduction in preterm birth rate in 2020. Hospital maternity statistics including those used for this study are published annually in a report which is publicly available.
    keywords: covid-19; maternity; pandemic; period
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        item: #781 of 7819
          id: cord-256051-87alqfkd
      author: Revzin, Margarita V.
       title: Multisystem Imaging Manifestations of COVID-19, Part 1: Viral Pathogenesis and Pulmonary and Vascular System Complications
        date: 2020-10-01
       words: 8866
      flesch: 29
     summary: The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome Hypercoagulability of COVID-19 patients in intensive care unit: A report of thromboelastography findings and other parameters of hemostasis Thromboinflammation and the hypercoagulability of COVID-19 Advance in the Management of Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic Indirect CT Venography at 80 kVp with Sinogram-Affirmed Iterative Reconstruction Compared to 120 kVp with Filtered Back Projection: Assessment of Image Quality and Radiation Dose Combined Direct and Indirect CT Venography (Combined CTV) in Detecting Lower Extremity Deep Vein Thrombosis Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Incidence of venous thromboembolism in hospitalized patients with COVID-19 D-dimer is Associated with Severity of Coronavirus Disease 2019: Chest radiography is a less sensitive modality for the detection of COVID-19 lung disease when compared with that CT, with a reported baseline chest radiography sensitivity of 69% (64).
    keywords: ards; cases; chest; complications; coronavirus; cov-2; covid-19; disease; fig; findings; imaging; infection; lung; patients; pneumonia; sars
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        item: #782 of 7819
          id: cord-256091-mrc9p1vw
      author: Jenkins, Wiley D.
       title: COVID‐19 During the Opioid Epidemic – Exacerbation of Stigma and Vulnerabilities
        date: 2020-04-11
       words: 1409
      flesch: 40
     summary: For example, rural health care barriers may be more pronounced than urban ones since rurality is generally characterized by lower incomes, limited economic and educational opportunities, increased rates of alcohol and tobacco use, and health care shortages. As described, barriers to health and health care among rural PWUD predate COVID-19, and the current crisis has the potential to exacerbate these issues.
    keywords: care; health; pwud; rural; use
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        item: #783 of 7819
          id: cord-256092-bph9ys72
      author: Hussain, Aneela N.
       title: Role of testosterone in COVID-19 patients - a double-edged sword?
        date: 2020-09-17
       words: 1576
      flesch: 33
     summary: Low testosterone levels in males have a direct correlation with the high probability of ICU admission and the worse disease outcome (ARDS, duration of ICU stay, mortality). Low testosterone levels in males have a direct correlation with the high probability of ICU admission and the worse disease outcome (ARDS, duration of ICU stay, mortality).
    keywords: covid-19; levels; patients; testosterone
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        item: #784 of 7819
          id: cord-256121-9bl1ztuc
      author: Reid, Michael J A
       title: Building a tuberculosis-free world while responding to the COVID-19 pandemic
        date: 2020-10-22
       words: 1303
      flesch: 34
     summary: Despite these challenges, there are opportunities for synergy to expand tuberculosis programmes, strengthen tuberculosis response, and increase resources towards ending tuberculosis as governments mobilise COVID-19 response efforts while maintaining existing tuberculosis programmes. We calculated the health spending due to these additional incident cases of tuberculosis using estimates of government tuberculosis spending per case 12 and outof-pocket spending on tuberculosis care and projected the additional annual health-care costs that would result from these excess tuberculosis cases in India, Kenya, and Ukraine.
    keywords: covid-19; month; response; tuberculosis
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        item: #785 of 7819
          id: cord-256132-ufs9kw3o
      author: AlAteeq, Deemah A.
       title: Perceived stress among students in virtual classrooms during the COVID-19 outbreak in KSA
        date: 2020-08-01
       words: 3033
      flesch: 51
     summary: Females had a significantly higher mean score of perceived stress level compared to males (22.75 versus 20.27; p Q27 -value ¼ 0.003). Females and university students showed a significant association with stress level (p-value = 0.003 and 0.049, respectively).
    keywords: covid-19; ksa; level; outbreak; stress; students; university
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        item: #786 of 7819
          id: cord-256135-v75qvb1i
      author: Persoon, Ilona F.
       title: A review of respiratory protection measures recommended in Europe for dental procedures during the COVID-19 pandemic
        date: 2020-07-30
       words: 713
      flesch: 28
     summary: In conclusion, the recommendations on respiratory protection when undertaking dental healthcare in European countries vary considerably. During the COVID-19 pandemic period, the World Health Organisation (WHO) recommends wearing respiratory protection when undertaking aerosol generating procedures (AGP) to reduce the risks of cross-infection between patients and healthcare worker (HCW) and vice versa 2 .
    keywords: covid-19; dental; protection
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        item: #787 of 7819
          id: cord-256157-jbidxfk0
      author: Ñamendys-Silva, Silvio A.
       title: Hospital mortality in mechanically ventilated COVID-19 patients in Mexico
        date: 2020-09-30
       words: 562
      flesch: 45
     summary: We analysed data collected in the General Epidemiology Directorate of the Mexican Ministry of Heath, which is an open-source dataset comprising of daily updated data of suspected COVID-19 cases that were confirmed by a positive test for SARS-CoV-2 [2]. key: cord-256157-jbidxfk0 authors: Ñamendys-Silva, Silvio A.; Gutiérrez-Villaseñor, Alan; Romero-González, Juan P. title: Hospital mortality in mechanically ventilated COVID-19 patients in Mexico date: 2020-09-30 journal: Intensive Care Med DOI: 10.1007/s00134-020-06256-3 sha: doc_id: 256157 cord_uid: jbidxfk0 nan Dear Editor, As of August 13 th , 2020, a total of 20,439,814 confirmed cases of coronavirus disease 2019 (COVID-19) have been reported to the World Health Organization, and 744,385 lives have been lost [1] .
    keywords: covid-19; patients
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        item: #788 of 7819
          id: cord-256159-7x45wd45
      author: McFee, R.B.
       title: INTRODUCTION - EMERGING PATHOGESN AND THE COVID-19 PANDEMIC
        date: 2020-07-28
       words: 758
      flesch: 37
     summary: The origin, transmission, and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak -an update on the status The biology of coronaviruses Coronaviruses post SARS: update on replication and pathogenesis SARS coronavirus: a new challenge for prevention and therapy Middle East respiratory syndrome coronavirus (MERS -CoV) announcement of the Cornoavirus Study Group Epidemiological, demographic, and clnical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study The incubation period of Coronavirus Disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application COVID-19 associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches Novel coronavirus disease (COVID-19): a pandemic (epidemiology, pathogenesis, and potential therapeutics) Clinical features of patients infected with 2019 novel coronavirus in Wuhan World Health Organization COVID-19 Resource Center COVID-19 coronavirus outbreak. www.worldometers.info/coronavirus Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2 Triple combination of interferon beta-1b, lopinavirritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open label, randomized, phase 2 trial Pharmacologic treatments for coronavirus disease 2019 (COVID-19); A review
    keywords: coronavirus; covid-19; sars
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        item: #789 of 7819
          id: cord-256166-4pvk3fqn
      author: Indini, Alice
       title: Reorganization of Medical Oncology Departments during COVID-19 Pandemic: a Nationwide Italian Survey
        date: 2020-04-06
       words: 2439
      flesch: 39
     summary: Patients with thoracic tumors and those who underwent pulmonary resection are to be considered a subgroup of high risk patients. Results show that the following measures for oncologic patients have been promptly implemented through the whole country: use of protective devices, triage of patients accessing the hospital, delay of non-urgent visits, and use of telemedicine.
    keywords: covid-19; health; italy; measures; oncologic; patients
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        item: #790 of 7819
          id: cord-256195-1hmzgwrw
      author: Izzy, Saef
       title: Characteristics and outcomes of Latinx patients with COVID-19 in comparison to other ethnic and racial groups
        date: 2020-09-01
       words: 4110
      flesch: 37
     summary: 15, 26 Our firsthand clinical experience with COVID-19 patients indicate that in addition to African American patients, a higher percentage of COVID-19 Latinx patients required hospitalization and critical care admission. 10, 11 Hypertension, heart disease, obesity, and diabetes are common comorbidities associated with hospitalization in COVID-19 patients.
    keywords: african; american; comorbidities; covid-19; disease; hospitalization; latinx; patients
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        item: #791 of 7819
          id: cord-256218-xv7aw4xn
      author: Vargas, Maria
       title: Additional Suggestions for Organ Donation During COVID-19 Outbreak
        date: 2020-06-16
       words: 669
      flesch: 27
     summary: Additional suggestions for organ donation during COVID-19 a Sudden isolation from other patients to minimize the risk of transmission from unknown COVID-19 cases COVID-19 testing on bronchoalveolar lavage and nasal cavity specimen Screening for 1.domicile, travel, or prolonged stay in the zones where COVID-19 cases were currently recognized 2.close contact with suspected or confirmed cases of COVID-19 3.close contact with patients with respiratory symptoms at risk of COVID-19 4.respiratory symptoms before the ICU admission Evaluation of the presence of possible COVID-19 respiratory like symptoms Performance of lung computed tomography to assess the presence of radiological patterns of COVID-19 Limit the access to the isolation room Permission to access only for healthcare personnel screened for no exposure to COVID-19 and without COVID-19 respiratory symptoms Allow the access only with personal protective equipment suggested for COVID-19 Organ procurement surgeons Coming from hospitals without COVID-19 cases Screening for: 1.domicile, travel, or prolonged stay in the zones where COVID-19 cases were currently recognized 2.close contact with suspected or confirmed cases of COVID-19 3.close contact with patients with respiratory symptoms at risk of COVID-19 Absence of possible COVID-19 respiratory symptoms We hope that our suggestions may improve the safety of organ donor and the safety of transplantation during the worldwide spread of COVID-19 cases.
    keywords: covid-19; organ
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        item: #792 of 7819
          id: cord-256223-g7gw02pf
      author: Dang, Anh Kim
       title: Evidence of COVID-19 Impacts on Occupations During the First Vietnamese National Lockdown
        date: 2020-09-03
       words: 3644
      flesch: 43
     summary: Compared to healthcare workers, being self-employed/unemployed/retired were less likely to suffer from “Increased workload and conflicts due to COVID-19” and “Disclosure and discrimination related to COVID-19 work exposure.” There were three sub-domains identified by EFA, including 1) Increased workload and conflicts due to COVID-19 (6 questions); 2) positive attitude towards stability in working condition (4 questions); 3) disclosure and discrimination related to COVID-19 work exposure (4 questions).
    keywords: covid-19; exposure; health; impacts; respondents; study; thi; work; workers
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        item: #793 of 7819
          id: cord-256226-hzgvioq6
      author: Sehgal, Vishal
       title: Sex, Sleep, Steroids, and Lifestyle: Unraveling the Coronavirus Disease 2019 Conundrum
        date: 2020-09-25
       words: 1775
      flesch: 44
     summary: The course of the disease process in COVID-19 is defined by the inflammatory versus anti-inflammatory process in the body. Other modalities like dexamethasone and anti-inflammatory monoclonal antibodies like tocilizumab, sarilumab, and siltuximab primarily aim to modulate proinflammatory immune response.
    keywords: covid-19; disease; immune; inflammation; state
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        item: #794 of 7819
          id: cord-256227-nl90gljl
      author: Dzobo, Mathias
       title: COVID-19: a perspective for lifting lockdown in Zimbabwe
        date: 2020-04-30
       words: 2380
      flesch: 50
     summary: To upscale Covid-19 testing, more laboratory personnel will have to be hired and trained to carry out diagnostic testing. Zimbabwe, like other low-and middle-income countries, faces the risk of a surge in Covid-19 infections and deaths as unrestricted movement starts to take place.
    keywords: country; covid-19; government; lockdown; pandemic; zimbabwe
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        item: #795 of 7819
          id: cord-256233-k9hdq3z8
      author: Lipsky, Martin S.
       title: Men and COVID-19: A Pathophysiologic Review
        date: 2020-09-16
       words: 4625
      flesch: 38
     summary: Inflammatory cytokines have a central role in the progression of COVID-19 infection. Several studies demonstrate that hypogonadism is associated with increased proinflammatory cytokines and that testosterone may play a role in regulating the cascade of events leading to progression of COVID-19 infection due to the cytokine storm (Mohamad et al., 2019) .
    keywords: cov-2; covid-19; differences; disease; et al; men; sars; sex; women
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        item: #796 of 7819
          id: cord-256255-wqpndl46
      author: Wang, Lang
       title: Prolonged prothrombin time at admission predicts poor clinical outcome in COVID-19 patients
        date: 2020-10-06
       words: 3711
      flesch: 47
     summary: Prothrombin time, concentration of fibrin degradation products, respiration rate and age were predictive factors for clinical outcomes of COVID-19 patients. S-Editor: Zhang H L-Editor: Filipodia P-Editor: Wang LL patients were critical (23.9%), 79 patients were severe (37.1%) and 83 patients were moderate (39%). Thus, early identification of COVID-19 patients at high risk is important for improving the clinical practice and outcomes.
    keywords: coagulation; covid-19; disease; group; patients; time
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        item: #797 of 7819
          id: cord-256260-9jatvium
      author: Han, Yuanyuan
       title: COVID-19 in a patient with long-term use of glucocorticoids: A study of a familial cluster
        date: 2020-04-08
       words: 2300
      flesch: 57
     summary: Unfortunately, COVID-19 patients can be infective before the disease onset and maintain infective ability during the convalescent phase [3, 4, 14] . In the family we report here, the index patient, Case 1, was from Wuhan and had contact with COVID-19 patients before she returned to Yiyang city.
    keywords: case; covid-19; days; february; patients; sars
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        item: #798 of 7819
          id: cord-256262-lwc4ghj2
      author: Gangneux, Jean-Pierre
       title: Invasive fungal diseases during COVID-19: We should be prepared
        date: 2020-04-06
       words: 1144
      flesch: 24
     summary: -To improve the diagnosis, in proposing an efficient syndromic molecular approach for fungal respiratory infection during ARDS that can be shared with all hospitals receiving COVID-19 patients -To Among various causes of morbidity and mortality in COVID-19 patients, the frequency and impact of co-infections has still been poorly studied, particularly in patients with an acute respiratory distress syndrome (ARDS).
    keywords: covid-19; infection; mortality; patients
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        item: #799 of 7819
          id: cord-256264-9pyn0l6w
      author: Halimi, Vesa
       title: Current regulatory approaches for accessing potential COVID-19 therapies
        date: 2020-05-16
       words: 1504
      flesch: 22
     summary: key: cord-256264-9pyn0l6w authors: Halimi, Vesa; Daci, Armond; Stojanovska, Simona; Panovska-Stavridis, Irina; Stevanovic, Milena; Filipce, Venko; Grozdanova, Aleksandra title: Current regulatory approaches for accessing potential COVID-19 therapies date: 2020-05-16 journal: J Pharm Policy Pract DOI: 10.1186/s40545-020-00222-6 sha: doc_id: 256264 cord_uid: 9pyn0l6w This commentary aims to elaborate challenges in the regulatory approaches for accessing and investigating COVID-19 potential therapies either with off-label use, compassionate use, emergency use or for clinical trials. There are several regulatory approaches for accessing potential therapies in COVID-19 and they can be classified as clinical trials, compassionate use, emergency use and off-label use (Table 1)
    keywords: covid-19; label; patients; therapies; use
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        item: #800 of 7819
          id: cord-256294-9gmn4fcj
      author: Almazrou, Saja H.
       title: Comparing the impact of Hydroxychloroquine based regimens and standard treatment on COVID-19 patient outcomes: A retrospective cohort study
        date: 2020-10-01
       words: 3012
      flesch: 43
     summary: Larger observational studies and RCTs that evaluate the efficacy of HCQ in COVID-19 patients in the Saudi population are urgently needed. Chloroquine and Hydroxychloroquine (HCQ) is among the promising treatment modalities for COVID-19 patients Geleris et al., 2020; Rosenberg et al., 2020; Shen et al., 2020) .
    keywords: covid-19; hcq; patients; study; treatment
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        item: #801 of 7819
          id: cord-256309-hbdrobn1
      author: Kow, Chia Siang
       title: Meta-analysis of Effectiveness of Statins in Patients with Severe COVID-19
        date: 2020-08-12
       words: 963
      flesch: 34
     summary: Statins are known inhibitors of MYD88 and could stabilize MYD88 levels in the presence of external stressors, which thus suggest their roles in protecting COVID-19 patients from the development of overwhelming inflammatory responses The pooled analysis revealed a significantly reduced hazard for fatal or severe disease with the use of statins (Figure 1 ; pooled HR=0.70; 95% CI 0.53-0.94) compared to non-use of statins in COVID-19 patients.
    keywords: covid-19; patients; statins; studies
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        item: #802 of 7819
          id: cord-256326-3ebcuzd6
      author: Liotta, Giuseppe
       title: Is social connectedness a risk factor for the spreading of COVID-19 among older adults? The Italian paradox
        date: 2020-05-21
       words: 2364
      flesch: 51
     summary: The association of social connectedness with the spread of COVID-19 among older Italian adults, hence older adult mortality rate, is not confirmed. key: cord-256326-3ebcuzd6 authors: Liotta, Giuseppe; Marazzi, Maria Cristina; Orlando, Stefano; Palombi, Leonardo title: Is social connectedness a risk factor for the spreading of COVID-19 among older adults?
    keywords: cases; covid-19; italy; population; years
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        item: #803 of 7819
          id: cord-256332-ha7tx1fo
      author: Gopal, Jeevan Prakash
       title: COVID-19 pandemic: Building organisational flexibility to scale transplant programs
        date: 2020-10-18
       words: 2578
      flesch: 37
     summary: It has been reported that transplant patients acquiring coronavirus disease 2019 (COVID-19) have increased mortality, with more atypical presentations and longer duration of virus shedding A trial of vaccine in transplant patients is definitely warranted and whether a pre-transplant patient should be in early vaccine trials is more controversial, if a vaccine becomes available.
    keywords: covid-19; donor; organ; pandemic; patients; transplant; transplantation
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        item: #804 of 7819
          id: cord-256351-q8lkhklw
      author: Di Giorgio, Angelo
       title: Health status of patients with Autoimmune Liver Disease during SARS-CoV-2 outbreak in northern Italy
        date: 2020-05-12
       words: 1380
      flesch: 38
     summary: Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Specific ACE2 Expression in Cholangiocytes May Cause Liver Damage After 2019-nCoV Infection The Facts During the Third Epidemic Uneventful course in IBD patients during SARS-CoV-2 outbreak in northern Italy Highlights for management of patients with Autoimmune Liver Disease during COVID-19 pandemia Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Report 13 -Estimating the number of infections and the impact of non-pharmaceutical interventions on COVID-19 in 11 European countries: Imperial College London Care of patients with liver disease during the COVID-19 pandemic: EASL-ESCMID Position Paper Liver injury in COVID-19: management and challenges COVID-19)Treatment Guidelines Interestingly, we found that the observed incidence of cases in our cohort of patients was not different from the estimated incidence in the general population, suggesting that AILD patients are not more susceptible to COVID-19 than the general population (7).
    keywords: covid-19; disease; liver; patients
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        item: #805 of 7819
          id: cord-256357-dlc8yb6j
      author: Augoustides, John G.
       title: Cardiopulmonary Resuscitation during the Coronavirus Crisis – important updates for the cardiothoracic and vascular anesthesia community
        date: 2020-04-28
       words: 2006
      flesch: 22
     summary: American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care American Heart Association focused update on advanced cardiovascular life support: use of advanced airways, vasopressors, and extracorporeal cardiopulmonary resuscitation during cardiac arrest: an update to the American Heart Association Guidelines for cardiopulmonary resuscitation and emergency cardiovascular care International consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations: summary from the Basic Life Support; Advanced Life Support Neonatal Life Support; Education and Implementation; and First Aid Task Forces Advanced cardiovascular life support -focus on airway management, vasopressor selection and rescue therapy with extracorporeal membrane oxygenation Cardiopulmonary resuscitation during the COVID-19 pandemic: a view from trainees on the frontline Interim guidance for basic and advanced life support in adults, children and neonates with suspected or confirmed COVID-19: from the Emergency Cardiovascular Care Committee and Get With the Guidelines®-Resuscitation Adult and Pediatric Task Forces of the American Heart American Association for Respiratory Care, American College of Emergency Physicians, The Society of Critical Care Anesthesiologists, and American Society of Anesthesiologists: Supporting Organizations: American Association of Critical Care Nurses and National EMS Physicians Extracorporeal membrane oxygenation -crucial considerations during the coronavirus crisis Cardiovascular considerations and consequences of coronavirus infectionperspectives for the cardiothoracic anesthesiologist and intensivist during the coronavirus crisis Critical care during the coronavirus crisis -challenges and considerations for the cardiothoracic and vascular anesthesia community Cardiovascular considerations for patients, health care workers, and health systems during the coronavirus disease 2019 (COVID-19) pandemic Perioperative echocardiography -key considerations during the coronavirus pandemic Perioperative echocardiography during the coronavirus crisisconsiderations in pediatrics and congenital heart disease Chinese Association of Anesthesiologists expert consensus on the use of perioperative ultrasound in coronavirus 2019 patients Anesthesia management and perioperative infection control in patients with the novel coronavirus Response and operating room preparation for the COVID-19 outbreak: a perspective from the National Heart Center Singapore Chinese Society of Anesthesiology expert consensus on anesthetic management of cardiac surgical patients with suspected or confirmed coronavirus disease 2019 Intensive care management of coronavirus disease (COVID-19): challenges and recommendations Consensus guidelines for managing the airway in patients with COVID-19 Association between in-hospital critical illness events and outcomes in patients on the same ward Fair allocation of scarce medical resources in the time of COVID-19 Palliative care for patients with advanced heart disease The role and response of palliative care and hospice services in epidemics and pandemics: a rapid review to inform practice during the COVID-19 pandemic Maximizing the calm before the storm: tiered surgical response plan for the novel coronavirus (COVID-19) Creating a palliative care inpatient response plan for COVID-19 -the UW Medicine experience How should US hospitals prepare for coronavirus disease Extracorporeal membrane oxygenation during adult noncardiac surgery and perioperative emergencies: a narrative review Clinical management of venoarterial extracorporeal membrane oxygenation Predictors of neurologic recovery in patients who undergo extracorporeal membrane oxygenation for refractory cardiac arrest Cardiac interventions in pregnancy and peripartum -a narrative review of the literature 6 The risk of viral aerosilization during airway management and consequent infection is considered high in the presence of COVID-19 infection.
    keywords: care; coronavirus; covid-19; life; resuscitation; support
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        item: #806 of 7819
          id: cord-256385-g1wcfrfi
      author: Badraoui, Riadh
       title: Acute respiratory distress syndrome: a life threatening associated complication of SARS-CoV-2 infection inducing COVID-19
        date: 2020-08-05
       words: 6081
      flesch: 37
     summary: The damaged endothelia show much more permeability to both water and proteins (exudate) and disrupt the alveolar capillary barrier (Kao et al., 2015; Vasudevan et al., 2004) . Reich et al., 2008; Yang et al., 2015;
    keywords: ace2; acute; ards; coronavirus; cov-2; covid-19; et al; infection; protein; receptor; sars; syndrome
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        item: #807 of 7819
          id: cord-256443-kejqbo1q
      author: Forbes, Nauzer
       title: Changes in Gastroenterology and Endoscopy Practices in Response to the COVID-19 Pandemic: Results from a North American Survey
        date: 2020-05-04
       words: 1191
      flesch: 40
     summary: Seventy-three individuals responded on behalf of their institutions, representing 62 U.S. At the time of response, most centers (46/71, 65%) were operating at ≤10% of their normal endoscopy volume, with 18 centers (25%) performing approximately 25% of normal volume. However, the postponement of non-urgent endoscopy will result in a surplus of procedures when clinical operations normalize.
    keywords: centers; covid-19; endoscopy; survey
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        item: #808 of 7819
          id: cord-256458-3fyul3k2
      author: Kolikonda, Murali Krishnan
       title: Association of Coronavirus Disease 2019 and Stroke: A Rising Concern
        date: 2020-08-13
       words: 1170
      flesch: 37
     summary: There is an association between COVID-19 illness in people and acute stroke. Is our COVID-19-focused health care system and media currently providing less attention to other serious conditions and emergencies like acute stroke? Medical facilities are encountering unusually long delays before patients seek attention for acute emergencies
    keywords: coronavirus; covid-19; patients; stroke
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        item: #809 of 7819
          id: cord-256482-xcoignha
      author: Kelley, Maureen
       title: An appeal for practical social justice in the COVID-19 global response in low-income and middle-income countries
        date: 2020-05-14
       words: 972
      flesch: 48
     summary: To optimise COVID-19 care, even as intensive care capacity is improved, gaps in affordable essential care that will benefit many should be prioritised because the disparity between the ability of high-income countries and LMICs to provide COVID-19 care is stark. Fourth, improvements in standards of critical care should not come at the expense of essential care and routine health services.
    keywords: care; covid-19; health
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        item: #810 of 7819
          id: cord-256500-nlavfnpt
      author: Zhang, Dan
       title: COVID-19 infection induces readily detectable morphological and inflammation-related phenotypic changes in peripheral blood monocytes, the severity of which correlate with patient outcome
        date: 2020-03-26
       words: 3506
      flesch: 42
     summary: A pneumonia outbreak associated with a new coronavirus of probable bat origin SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice A pathological report of three COVID-19 cases by minimally invasive autopsies SARS-coronavirus replication in human peripheral monocytes/macrophages SARS coronavirus spike protein-induced innate immune response occurs via activation of the NF-kappaB pathway in human monocyte macrophages in vitro SARS-CoV regulates immune function-related gene expression in human monocytic cells Aberrant pathogenic GM-CSF + T cells and inflammatory CD14 + CD16 + monocytes in severe pulmonary syndrome patients of a new coronavirus Pathogenic T cells and inflammatory monocytes incite inflammatory storm in severe COVID-19 patients The landscape of lung bronchoalveolar immune cells in COVID-19 revealed by single-cell RNA sequencing Clinical experience of IL-6 blockade in rheumatic diseases -implications on IL-6 biology and disease pathogenesis Toxicity and management in CAR T-cell therapy Effective Treatment of Severe COVID-19 Patients with Tocilizumab COVID-19: consider cytokine storm syndromes and immunosuppression Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial Baricitinib as potential treatment for 2019-nCoV acute respiratory disease No reuse allowed without permission. 24.20042655 doi: medRxiv preprint To investigate the potential effects of FSC-low monocytes and FSC-low/FSC-high monocytes on the discharge of COVID-19 patients from hospital, we performed Kaplan-Meier survival analysis.
    keywords: covid-19; fsc; high; monocytes; patients; preprint; sars
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        item: #811 of 7819
          id: cord-256508-ce59ovan
      author: Asselah, Tarik
       title: COVID-19: discovery, diagnostics and drug development
        date: 2020-10-08
       words: 9235
      flesch: 42
     summary: If RT-qPCR-based molecular assays for detecting SARS CoV-2 in respiratory specimens remain the current reference standard for diagnosis, point-of care technologies, and serologic immunoassays have also rapidly emerged [57] Indeed, antibodies to this protein are frequently detected in COVID-19 patient [64]
    keywords: antibodies; cell; coronavirus; cov-2; covid-19; disease; drug; human; immune; infection; liver; patients; remdesivir; samples; sars; study; testing; tests; treatment; virus
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        item: #812 of 7819
          id: cord-256542-v8cyfo66
      author: Heffner, Joseph
       title: Emotional responses to prosocial messages increase willingness to self-isolate during the COVID-19 pandemic
        date: 2021-02-15
       words: 5975
      flesch: 30
     summary: Indeed, some recent research illustrates that prosocial public health messages that underscore behaviors linked to societal and communal benefits (e.g., help protect your fellow citizens)-rather than focusing on behaviors that only benefit the self (e.g., protect yourself)-may be an especially effective method (Kelly & Hornik, 2016; Li, Taylor, Atkins, Chapman, & Galvani, 2016) for communicating public health recommendations related to COVID-19 (Jordan, Yoeli, & Rand, 2020) . Research on message interventions illustrates that reported behavior change does not always coincide with actual behavior changes in the real world (Gibbons, Gerrard, Ouellette, & Burzette, 1998) .
    keywords: arousal; change; covid-19; fear; health; intervention; isolate; messages; prosocial; self; threat; willingness
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        item: #813 of 7819
          id: cord-256553-iw5squ6n
      author: Neiva, Mariane Barros
       title: Brazil: the emerging epicenter of COVID-19 pandemic
        date: 2020-10-21
       words: 3641
      flesch: 54
     summary: Along with the comparison of countries, we also compared the first and second positions in the worldwide rank of case numbers provided by 1 . Supported by the quantitative information in Figure 2b demonstrating that Brazil is expected to overtake the US in total number of cases (proportionally by population size), the current low isolation rates, low population testing percentage with consequently high under detection, high daily cases, and death rates all suggest that Brazil has eased its restrictions prematurely and may face severe consequences in the near future as a result, such as becoming the next global epicenter of the pandemic.
    keywords: brazil; cases; countries; country; covid-19; data; deaths; new; number
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        item: #814 of 7819
          id: cord-256556-1zea3wa1
      author: Lou, Yan
       title: Clinical Outcomes and Plasma Concentrations of Baloxavir Marboxil and Favipiravir in COVID-19 Patients: An Exploratory Randomized, Controlled Trial
        date: 2020-10-25
       words: 4234
      flesch: 43
     summary: To determine whether the apparent lack of benefits by the addition of either baloxavir marboxil or favipiravir is related to their pharmacological exposure in the COVID-19 patients, drug concentrations were measured in the patients. This study aims to evaluate the clinical outcomes and plasma concentrations of baloxavir acid and favipiravir in COVID-19 patients.
    keywords: baloxavir; concentrations; covid-19; favipiravir; group; marboxil; patients; treatment; trial
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        item: #815 of 7819
          id: cord-256565-59bnifxm
      author: Lebwohl, Mark
       title: Reply to: “COVID-19, syphilis, and biologic therapies for psoriasis and psoriatic arthritis: A word of caution”
        date: 2020-04-10
       words: 502
      flesch: 38
     summary: key: cord-256565-59bnifxm authors: Lebwohl, Mark; Rivera-Oyola, Ryan; Murrell, Dedee F. title: Reply to: “COVID-19, syphilis, and biologic therapies for psoriasis and psoriatic arthritis: A word of caution” date: 2020-04-10 journal: J Am Acad Dermatol DOI: 10.1016/j.jaad.2020.03.103 sha: doc_id: 256565 cord_uid: 59bnifxm nan Reply to: 'COVID-19, syphilis, and biologic therapies for psoriasis and psoriatic arthritis: A word of caution' To the Editor: We thank Dr Kansal 1 from the All India Institute of Medical Sciences for her pertinent comments in response to our publication on the use of biologic agents for psoriasis patients in the current COVID-19 pandemic. Finally, we know that dupilumab, in addition to treating atopic dermatitis, which in itself can be debilitating, also treats asthma, which could be a complicating factor in COVID-19 infection.
    keywords: biologic; covid-19
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        item: #816 of 7819
          id: cord-256568-mbkrg98v
      author: Jantzen, R.
       title: Epidemiological and socio-economic characteristics of the COVID-19 spring outbreak in Quebec, Canada: A population-based study
        date: 2020-09-01
       words: 7910
      flesch: 50
     summary: Both the proportion of tested participants for COVID-19 and positive individuals among those being tested are consistent with those reported in Quebec at the closure of our survey (tested: CaG 8.0% Among the 4,855 individuals who experienced at least one COVID-related symptom (as defined above), 1,022 declared that their first action was to call or consult their family doctor (39.3%), to call the 811 or a dedicated coronavirus hotline (24.6%), to go to the pharmacy (24.6%), to the hospital emergency room (6.4%) or to a COVID-19 screening clinic (5.1%). Individuals changed their transport habits because of the lockdown (923), being afraid of COVID-19 exposure (522), quarantine/in self-isolation (206) or COVID-19 symptoms (11) .
    keywords: covid-19; exposure; health; individuals; license; medrxiv; participants; population; preprint; symptoms
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        item: #817 of 7819
          id: cord-256596-ejuyfto6
      author: Field, Robert I.
       title: Genetics and COVID-19: How to Protect the Susceptible
        date: 2020-08-29
       words: 1391
      flesch: 35
     summary: Those born with genetic susceptibility will always have it, while those who lack immunity because they have not been exposed to the virus can later acquire it. The COVID-19 Host Genetics Initiative, a global initiative to elucidate the role of host genetic factors in susceptibility and severity of the SARS-CoC-2 virus pandemic New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis Comment: Ten reasons why immunity passports are a bad idea Caveat emptor: How the intersection of big data and consumer genomics exponentially increases information privacy risks.
    keywords: covid-19; research; susceptibility
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        item: #818 of 7819
          id: cord-256634-gg8hptfg
      author: Rhodes, N. J.
       title: Multicenter point-prevalence evaluation of the utilization and safety of drug therapies for COVID-19
        date: 2020-06-06
       words: 4112
      flesch: 46
     summary: Patients were identified at each site according to institutional guidelines for identification and monitoring of COVID-19 patients. Adverse drug reactions were defined based upon existing knowledge of the side effect profiles of the agents evaluated as well as the existing literature on adverse events observed in COVID-19 patients at the time of the study.
    keywords: covid-19; drug; medrxiv; patients; preprint; remdesivir; therapies; therapy
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        item: #819 of 7819
          id: cord-256665-p9vbeffv
      author: Kenyon, Chris
       title: The Forrest Gump approach to preventing severe COVID-19 – reverse the predisposing pro-inflammatory state with exercise
        date: 2020-05-06
       words: 812
      flesch: 35
     summary: 123 Allergy Hyperinflammation and 125 derangement of Renin-Angiotensin-Aldosterone System in COVID-19: a novel hypothesis for 126 clinically suspected hypercoagulopathy and microvascular immunothrombosis A hypothesis for pathobiology and treatment of COVID-19: the 129 centrality of ACE1/ACE2 imbalance Elevated 132 serum levels of angiotensin-converting enzyme in patients with diabetic retinopathy Inflammageing: chronic inflammation in ageing, cardiovascular 135 disease, and frailty Imbalanced 137 host response to SARS-CoV-2 drives development of COVID-19 -7) participates in enhanced skeletal muscle insulin sensitivity after a bout 141 of exercise 144 Two protocols of aerobic exercise modulate the counter-regulatory axis of the renin-145 angiotensin system Running as a key 148 lifestyle medicine for longevity Influence of physical activity on hypertension and cardiac 150 structure and function What 152 interventions should we add to weight reducing diets in adults with obesity? Microbes Infect DOI: 10.1016/j.micinf.2020.05.003 sha: doc_id: 256665 cord_uid: p9vbeffv nan The Forrest Gump approach to preventing severe COVID-19 -reverse the predisposing 1 pro-inflammatory state with exercise 2 chronic diseases predispose to severe disease is that they are associated with a pro-33 inflammatory state and an imbalance between the pro-inflammatory angiotensin converting Exercise has also consistently been shown to be an effective way to reduce blood pressure in 70 hypertensives [15] .
    keywords: covid-19; disease; exercise
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        item: #820 of 7819
          id: cord-256676-b7p92sb1
      author: Syed, Faiza
       title: Estimation of the Final Size of the COVID-19 Epidemic in Pakistan
        date: 2020-04-06
       words: 1807
      flesch: 51
     summary: The data on the number of daily reported cases also reflects a general increasing trend as testing for COVID-19 gathers pace (figure 5.2). https://doi.org/10.1101/2020.04.01.20050369 doi: medRxiv preprint The NIH Pakistan data for the cumulative cases and daily reported cases was plotted to observe the increase in number of cases for a period of 33 days.
    keywords: cases; covid-19; pakistan; preprint
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        item: #821 of 7819
          id: cord-256688-yy7abob9
      author: Chavez, Summer
       title: Coronavirus Disease (COVID-19): A primer for emergency physicians
        date: 2020-03-24
       words: 6440
      flesch: 47
     summary: COVID-19 pushing Italian ICUs toward collapse Novel Coronavirus (2019-nCoV) flowchart for healthcare professionals A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Clinical characteristics of Coronavirus Disease 2019 in China Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected COVID-19) Interim Infection Prevention and Control Recommendations Novel Coronavirus (2019-nCoV) healthcare infection prevention and control FAQs for COVID-19 COVID-19: what is next for public health? COVID-19): evaluating and testing persons for Coronavirus Disease 2019 (COVID-19) Novel Coronavirus (2019-nCoV) evaluating and reporting PUI COVID-19) Interim Guidance for Emergency Medical Services (EMS) Systems and 911 Public Safety Answering Points (PSAPs) for COVID-19 in the United States Novel Coronavirus (2019-nCoV) infection control Surviving sepsis campaign: guidelines on the management of critically ill adults with Coronavirus Disease Infection prevention and control for coronavirus disease (COVID-19): interim guidance for acute healthcare settings Anesthesia Patient Safety Foundation Novel Coronavirus (2019-nCoV) Testing Novel Coronavirus (2019-nCoV) information for laboratories COVID-19 requests for diagnostic panels and virus COVID-19) interim guidelines for collecting, handling, and testing clinical specimens from persons under investigation (PUIs) for Coronavirus Disease 2019 (COVID-19) Detection of SARS-CoV-2 in different types of clinical specimens Correlation of chest CT and RT-PCR testing in Coronavirus Disease 2019 (COVID-19) in China: a report of 1014 cases. Up to 94% of COVID-19 cases were reported to originate from Hubei Province in December 2019; as of March 2020, the greatest number of new cases are now being reported in Italy, Spain, Germany, and the United States (U.S.) (Figs. 3 and 4)
    keywords: cases; coronavirus; covid-19; disease; emergency; health; infection; ncov; novel; patients; pneumonia; risk; sars; study; symptoms
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        item: #822 of 7819
          id: cord-256689-k7to2amn
      author: Lombardo, Eduardo
       title: Publication of COVID‐19 case reports: are we hurrying?
        date: 2020-06-09
       words: 702
      flesch: 46
     summary: Evidence-based medicine considers that clinical case reports are the types of study classified with the lowest level of evidence given their methodological composition (Burns, Rohrich and Chong, 2011) . In the other hand, from a practical point of view, clinical case reports have their importance based on the academic scope and, mainly, within the scope of public policies.
    keywords: case; covid-19
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        item: #823 of 7819
          id: cord-256696-leqakx22
      author: Sherratt, K.
       title: Evaluating the use of the reproduction number as an epidemiological tool, using spatio-temporal trends of the Covid-19 outbreak in England
        date: 2020-10-20
       words: 5760
      flesch: 50
     summary: We compared the divergence between Rt estimates with spatio-temporal variation in case detection, and the proportion at risk of severe disease, represented by the age distribution of test positive cases and hospital admissions and the proportion of deaths in care homes. Based on the work presented here we now provide Rt estimates, updated each day, for test positive cases, admissions and deaths in each NHS region and in England.
    keywords: admissions; cases; covid-19; data; deaths; estimates; source; test; time
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        item: #824 of 7819
          id: cord-256705-gexh2wtd
      author: Prescott, K.
       title: COVID-19: how prepared are front-line healthcare workers in England?
        date: 2020-04-24
       words: 2070
      flesch: 56
     summary: However, if there is to be success in managing this pandemic, levels of HCW knowledge must rapidly increase. It was sent to front line HCW at Nottingham University Hospitals NHS Trust and Birmingham Women's & Children's NHS Foundation Trust.
    keywords: covid-19; hcw; hospital; respondents; survey
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        item: #825 of 7819
          id: cord-256717-bnzbhetc
      author: Paton, Calum
       title: Insouciance and inexperience: A deadly combination when dealing with COVID‐19
        date: 2020-06-03
       words: 2473
      flesch: 53
     summary: https://orcid.org/0000-0002-5476-1126 Presentation at UK government's daily 5pm briefing See also The Telegraph (UK), online SARS-CoV-2 pandemics: the lack of critical reflection addressing short-term and long-term challenges BBC Radio 4 Today programme BBC 1 TV Testimony to UK House of Commons Health and Social Care Committee Statement After COBRA (Cabinet Office Briefing Rooms) Johnson did not resist immediate action to limit inward flights to the UK and quarantine passengers and, later, control movement within the country because he is a theoretical libertarian as alleged by some on the Left or imbued with a mistrust of government in the style of some U.S. far-right activists.
    keywords: covid-19; government; science; test; virus
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        item: #826 of 7819
          id: cord-256719-njrjepor
      author: Balsari, Satchit
       title: COVID-19 care in India: the course to self-reliance
        date: 2020-08-24
       words: 1011
      flesch: 50
     summary: key: cord-256719-njrjepor authors: Balsari, Satchit; Sange, Mansoor; Udwadia, Zarir title: COVID-19 care in India: the course to self-reliance date: 2020-08-24 journal: Lancet Glob Health DOI: 10.1016/s2214-109x(20)30384-3 sha: doc_id: 256719 cord_uid: njrjepor nan The public health response to COVID-19 in India has been highly centralised, resulting in a homogenous strategy applied across a sixth of the world's population. npr Respiratory support in COVID-19 patients, with a focus on resource-limited settings Dexamethasone in hospitalized patients with Covid-19-preliminary report
    keywords: care; covid-19; india; people
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        item: #827 of 7819
          id: cord-256723-2eab6g7i
      author: Chen, Taige
       title: Lessons from a patient with severe aplastic anemia complicated with COVID-19
        date: 2020-07-20
       words: 343
      flesch: 38
     summary: key: cord-256723-2eab6g7i authors: Chen, Taige; Lu, Xiaofan; Wang, Yang; Wang, Jun title: Lessons from a patient with severe aplastic anemia complicated with COVID-19 date: 2020-07-20 journal: Asian J Surg DOI: 10.1016/j.asjsur.2020.07.007 sha: doc_id: 256723 cord_uid: 2eab6g7i COVID-19 patients with preexisting diseases are at high risk of worse clinical outcomes. We reported a case of a patient with severe aplastic anemia complicated with COVID-19 who improved but turned worse rapidly and died in septic shock.
    keywords: aplastic; covid-19
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        item: #828 of 7819
          id: cord-256736-ep9aqpfs
      author: Fathi, Nazanin
       title: Lymphopenia in COVID‐19: Therapeutic opportunities
        date: 2020-06-03
       words: 1617
      flesch: 26
     summary: Rezaei http://orcid.org/0000-0002-3836-1827 Chronic hepatitis C virus infection triggers spontaneous differential expression of biosignatures associated with T cell exhaustion and apoptosis signaling in peripheral blood mononucleocytes Viral persistence and chronicity in hepatitis C virus infection: role of T-cell apoptosis, senescence and exhaustion Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity Chronic antigen stimulation alone is sufficient to drive CD8+ T cell exhaustion Human immunopathogenesis of severe acute respiratory syndrome (SARS) Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome A rationale for using steroids in the treatment of severe cases of H5N1 avian influenza Regulation of myelopoiesis by proinflammatory cytokines in infectious diseases Promising therapies that used for other viruses with distinctive pathobiology condition Drugs, biological, or chemical modifiers Janus kinase inhibition, IL-1 and IL-6 receptor antagonist IL-1 receptor antagonist, IL-7 agonists, HSCT Exhausted lymphocytes Histone deacetylase(iv Adoptive therapy with T cells/NK cells Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 IFN-β induces greater antiproliferative and proapoptotic effects and increased p53 signaling compared with IFN-α in PBMCs of adult T-cell leukemia/lymphoma patients COVID-19: CD8 + T cells release the perforin and granzymes A and B that induce apoptosis in viral infected cells (Thevarajan et al., 2020) .
    keywords: cells; covid-19; immune; infection; patients
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        item: #829 of 7819
          id: cord-256743-v8vegody
      author: Papes, Dino
       title: Redundancy and methodological issues in articles on COVID‐19
        date: 2020-06-07
       words: 1319
      flesch: 37
     summary: We have determined three main issues in COVID-19 publications: 1) Non-evidence based information/recommendation. In this research, we aimed to evaluate the trend in the number of publication on COVID-19, quantify publication redundancy and determine methodological issues in publications on COVID-19.
    keywords: article; copyright; covid-19; publications
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        item: #830 of 7819
          id: cord-256746-ggnd8y06
      author: Flythe, Jennifer E.
       title: Characteristics and Outcomes of Individuals With Pre-existing Kidney Disease and COVID-19 Admitted to Intensive Care Units in the United States
        date: 2020-09-19
       words: 4414
      flesch: 35
     summary: [2-9] for dialysis patients; 7 [3-10] for CKD patients; 7 [4-10] for patients without pre-existing kidney disease). Compared to patients without pre-existing kidney disease, dialysis patients had a higher risk of 28-day in-hospital death (adjusted HR 1.41; 95% CI 1.09, 1.81), while patients with CKD had an intermediate risk (adjusted HR 1.25; 95% CI 1.08, 1.44).
    keywords: ckd; covid-19; dialysis; disease; hospital; kidney; kidney disease; patients
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        item: #831 of 7819
          id: cord-256752-x7h4tix2
      author: Yu, Hua
       title: Coping style, social support and psychological distress in the general Chinese population in the early stages of the COVID-19 epidemic
        date: 2020-08-27
       words: 5767
      flesch: 40
     summary: Differences in demographic characteristics, coping style and social support between respondents who suspected or did not suspect that they had COVID-19 Only one of 256 respondents with suspected infection showed low psychological distress, indicating that suspected cases in our sample had high psychological distress. Social support from partners and family members has been associated with well-being [40] , and existing literature reveals considerable differences in social support among married, formerly married, and never-married people: unmarried people are less likely than married people to report having close family members or friends
    keywords: covid-19; distress; factors; health; infection; outbreak; population; respondents; social; support
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        item: #832 of 7819
          id: cord-256786-7gca01lr
      author: Bartilotti‐Matos, F
       title: Pearls and Pitfalls: two contrasting HIV diagnoses in the COVID‐19 era and the case for screening
        date: 2020-08-13
       words: 1316
      flesch: 52
     summary: Clinical characteristics and outcomes in people living with HIV hospitalized for COVID-19 COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients Coronavirus disease 2019 (COVID-19) outcomes in HIV/AIDS patients: a systematic review Clinical features and outcomes of HIV patients with coronavirus disease 2019 COVID-19 in patients with HIV: clinical case series Recovery from COVID-19 in two patients with coexisted HIV infection HIV in the United Kingdom: key: cord-256786-7gca01lr authors: Bartilotti‐Matos, F; Davies, P. title: Pearls and Pitfalls: two contrasting HIV diagnoses in the COVID‐19 era and the case for screening date: 2020-08-13 journal: J Med Virol DOI: 10.1002/jmv.26428 sha: doc_id: 256786 cord_uid: 7gca01lr The risk of coronavirus disease 2019 (COVID‐19) for people living with HIV (PLWH) is poorly understood.
    keywords: case; covid-19; hiv; patients
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        item: #833 of 7819
          id: cord-256795-j66tcamq
      author: Wang, Jin
       title: The impacts of a COVID-19 epidemic focus and general belief in a just world on individual emotions()
        date: 2020-08-20
       words: 2020
      flesch: 37
     summary: A revised Positive and Negative Affect Scale (PANAS, Huang et al., 2003) that has often been used to measure general individual emotions under normal conditions combined with a measurement of individual emotions during the COVID-19 epidemic period (Wang & Gao, 2020; Guo et al., 2020) were used, and 10 emotion words were selected in this experiment. key: cord-256795-j66tcamq authors: Wang, Jin; Wang, Zhuo; Liu, Xiaojin; Yang, Xiaofan; Zheng, Meilin; Bai, Xuejun title: The impacts of a COVID-19 epidemic focus and general belief in a just world on individual emotions() date: 2020-08-20 journal: Pers Individ Dif DOI: 10.1016/j.paid.2020.110349 sha: doc_id: 256795 cord_uid: j66tcamq Whether the general belief in a just world (GBJW) can protect individual emotions during a major disaster is a matter of debate.
    keywords: emotions; epidemic; gbjw; individual
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        item: #834 of 7819
          id: cord-256862-038rrdtp
      author: Oland, Gabriel
       title: Prospective Clinical Validation of 3D Printed Nasopharyngeal Swabs for Diagnosis of COVID-19
        date: 2020-10-22
       words: 2005
      flesch: 37
     summary: Experimental swab samples were collected consecutively to the control and transported in sterile polypropylene tubes with 3mL saline (0.9% sodium chloride in water) as transport media. Quality design controls and early clinical use have demonstrated similar safety profiles to NP swabs currently on the market (8) .
    keywords: covid; covid-19; nasopharyngeal; patients; swab
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        item: #835 of 7819
          id: cord-256864-v3mxcwru
      author: Tang, Yueting
       title: Selection of an Optimal Combination Panel to Better Triage COVID-19 Hospitalized Patients
        date: 2020-10-27
       words: 5127
      flesch: 39
     summary: The rate of admission to ICU was 18.75% vs.14.29%; while discharge rate was 15.63% vs 50.0%, for the critical vs severe patients, respectively. Panel three (WBC, PCT, IL-6, IL-10, and SOD) had much better performance in the initial triage model in risk prediction for the critical vs severe patients.
    keywords: biomarkers; covid-19; disease; group; il-10; il-6; infection; panel; patients; pct; risk; serum; sod
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        item: #836 of 7819
          id: cord-256878-3e2fcx9k
      author: Moadel, Renee M.
       title: Remaining Academically Connected While Socially Distant: Leveraging Technology to Support Dispersed Radiology and Nuclear Medicine Training Programs in the Era of COVID-19
        date: 2020-04-15
       words: 900
      flesch: 35
     summary: Diagnosis and management of COVID-19 disease COVID-19 related guidance from the U.S. Centers for Disease Control and Prevention COVID-19 related guidance from the U.S. Department of Health & Human Services. All means of communication (messaging, audio calls, and video calls) are accessed from the workstation and all department members can be quickly reached through a single interface, independent of their location.
    keywords: communication; control; covid-19; programs
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        item: #837 of 7819
          id: cord-256888-tdx12ccj
      author: Bradley, Benjamin T
       title: Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series
        date: 2020-07-16
       words: 5010
      flesch: 42
     summary: Patient 3 and patient 9 also had microthrombi in the trachea, although in patient 3 this was qualified by chronic tracheostomy. We hypothesise that there was a subclinical period during which lung injury was occurring in COVID-19 patients with organising diffuse alveolar disease who died in the week after symptom onset.
    keywords: cov-2; covid-19; diffuse; disease; findings; infection; injury; lung; particles; patients; sars
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        item: #838 of 7819
          id: cord-256891-as6tbfrh
      author: Rubin, Samuel J. S.
       title: Clinical characteristics associated with COVID-19 severity in California
        date: 2020-03-30
       words: 1140
      flesch: 35
     summary: Limitations of this study include lack of some data on disease progression due to retrospective design and potential selection bias of patients with severe disease more likely to have SARS-CoV-2 testing and extensive charting. Several factors, including age-related changes in the immune system and other physiological processes could contribute to COVID-19 disease severity.
    keywords: disease; license; preprint
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        item: #839 of 7819
          id: cord-256893-3sh87h2x
      author: Yang, Li
       title: COVID-19: immunopathogenesis and Immunotherapeutics
        date: 2020-07-25
       words: 5360
      flesch: 33
     summary: A Novel Coronavirus from patients with Pneumonia in China Clinical features of patients infected with 2019 novel coronavirus in Wuhan Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical characteristics of 138 hospitalized patients with 2019 Novel Coronavirus-infected Pneumonia in Wuhan, China Significant changes of peripheral T lymphocyte subsets in patients with severe acute respiratory syndrome Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome Different features of Vdelta2 T and NK cells in fatal and non-fatal human Ebola infections Immune parameters and outcomes during Ebola virus disease Clinical features and progression of acute respiratory distress syndrome in coronavirus disease 2019 Laboratory abnormalities in patients with COVID-2019 infection Pathological findings of COVID-19 associated with acute respiratory distress syndrome Dysregulation of immune response in patients with COVID-19 in Wuhan, China Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients SARS-CoV-2 infection in children Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19): A multi-center study in Wenzhou city Clinical characteristics of imported cases of COVID-19 in Jiangsu province: a multicenter descriptive Study Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series A new coronavirus associated with human respiratory disease in China A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster A pneumonia outbreak associated with a new coronavirus of probable bat origin Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical characteristics of Coronavirus disease 2019 in China Characteristics of lymphocyte subsets and cytokines in peripheral blood of 123 hospitalized patients with 2019 novel coronavirus pneumonia (NCP) Reduction and functional exhaustion of T cells in patients with Coronavirus Disease 2019 (COVID-19) Immune characteristics predict outcome of severe and critical COVID-19 patients Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals T cell responses to whole SARS coronavirus in humans Aberrant pathogenic GM-CSF+T cells and inflammatory CD14 +CD16+monocytes in severe pulmonary syndrome patients of a new coronavirus The significance of OX40 and OX40L to Tcell biology and immune disease 4-1BB co-stimulation enhances human CD8(+) T cell priming by augmenting the proliferation and survival of effector CD8(+) T cells Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 Restoration of leukomonocyte counts is associated with viral clearance in COVID-19 hospitalized patients Functional exhaustion of antiviral lymphocytes in COVID-19 patients Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients Immune phenotyping based on neutrophil-to-lymphocyte ratio and IgG predicts disease severity and outcome for patients with COVID-19 Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019 Antibody responses to SARS-CoV-2 in patients with COVID-19 Assessment of SARS-CoV-2 serological tests for the diagnosis of COVID-19 through the evaluation of three immunoassays: two automated immunoassays (Euroimmun and Abbott) and one rapid lateral flow immunoassay (NG Biotech) Immunopathogenesis of coronavirus infections: implications for SARS Fighting COVID-19 exhausts T cells COVID-19: immunopathology and its implications for therapy Immune dysfunction leads to mortality and organ injury in patients with COVID-19 in China: insights from ERS-COVID-19 study The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice The interplay between neutrophils and microbiota in cancer COVID-19: immunopathogenesis and Immunotherapeutics Yang Management of cytokine release syndrome related to CAR-T cell therapy Cytokine release syndrome Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing TH17 responses in cytokine storm of COVID-19: an emerging target of JAK2 inhibitor Fedratinib Expression of B and T lymphocyte attenuator (BTLA) in macrophages contributes to the fulminant hepatitis caused by murine hepatitis virus strain-3 VSIG4 inhibits proinflammatory macrophage activation by reprogramming mitochondrial pyruvate metabolism Antibody-dependent enhancement of SARS coronavirus infection and its role in the pathogenesis of SARS Signals of T h 2 immune response from COVID-19 patients requiring intensive care Antibody-dependent enhancement of severe dengue disease in humans The microbiome and innate immunity IL-1beta is a key cytokine that induces trypsin upregulation in the influenza virus-cytokine-trypsin cycle A case series of children with 2019 novel coronavirus infection: clinical and epidemiological features Immune responses in COVID-19 and potential vaccines: lessons learned from SARS and MERS epidemic.
    keywords: cases; cell; clinical; coronavirus; cov-2; covid-19; cytokine; disease; levels; patients; sars
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        item: #840 of 7819
          id: cord-256961-935r7w01
      author: Lu, S.
       title: Effectiveness and Safety of Glucocorticoids to Treat COVID-19: A Rapid Review and Meta-Analysis
        date: 2020-04-22
       words: 5151
      flesch: 50
     summary: The quality of evidence on the results on mortality in COVID-19 and SARS studies, of very low quality, and in MERS studies of low quality (Tables 4-6). In mild cases of SARS glucocorticoids even increased the risk of death (RR=3.6, 95% CI: 1.9 to 6.9).
    keywords: author; copyright; funder; holder; medrxiv; patients; perpetuity; preprint; review
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        item: #841 of 7819
          id: cord-256975-ma9abdj8
      author: Motterle, Giovanni
       title: The impact of COVID-19 pandemic on urological emergencies: a single-center experience
        date: 2020-05-23
       words: 2734
      flesch: 41
     summary: METHODS: we retrospectively reviewed urgent urological consultations requested by the Emergency Department (ED) of Padua University Hospital in the 36-day period between February 22nd and March 30th, 2020 and compared them to the prior year cases within a similar time frame (February 24th to March 31st, 2019). Urgent urology practice was affected during COVID-19 pandemic with a remarkable reduction in urgent urological consultations; furthermore, a higher risk of admissions was observed in 2020.
    keywords: admission; consultations; covid-19; number; period
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        item: #842 of 7819
          id: cord-257003-749zpxuy
      author: Onchonga, David
       title: Assessing the Prevalence of Self-Medication among Healthcare Workers before and during the 2019 SARS-CoV-2 (COVID-19) Pandemic in Kenya
        date: 2020-08-14
       words: 3317
      flesch: 41
     summary: Self-medication also known as self-care and/or self-administration of medication is a common practice across the world (Hughes et al., 2001) and it involves situations where individuals, families, and/or communities take medicines to treat health conditions or symptoms without prescription or diagnosis from a qualified healthcare professional (Bennadi, 2014; Guzmán et al., 2000; Ruiz, 2010) . About 16.9% (n= 64) obtained the medicines from the primary health facility, 56.5% (n=214) from pharmacy stores while 26.6% (n=101) from hospital pharmacies before the outbreak, while, 89.5% (n=340) obtained medication from pharmacy stores and only10.5% (n=39) from primary health facilities.
    keywords: healthcare; medication; outbreak; self; study; workers
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        item: #843 of 7819
          id: cord-257056-0z3qiz6p
      author: Kivuti-Bitok, L. W.
       title: System Dynamics Model of Possible Covid-19 Trajectories Under Various Non-Pharmaceutical Intervention Options in Low Resource Setting.
        date: 2020-10-08
       words: 3841
      flesch: 44
     summary: The suggested interventions would delay the epidemic peak of Covid-19 to between late Nov 2020 and early December 2020 with an estimated13M cases a 500 thousand reduction in Covid-19 cases and 32.4 deaths( a reduction in 1400 deaths). As demonstrated in Fig 11, realistic intervention levels of all the selected non pharmaceutical interventions; effectiveness of physical distancing and hand hygiene at 65%, curfew at 80%, quarantining at 80% and person to person contact at maximum of 30) would result to a delay of peak of Covid-19 cases from 178 th day since first confirmed infection to a peak of 246 th day allowing approximately 67 extra days for preparedness of health care system.
    keywords: covid-19; license; medrxiv; medrxiv preprint; model; october; preprint; review
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        item: #844 of 7819
          id: cord-257076-uh98ilhr
      author: Lionis, Christos
       title: Challenges, priorities and tasks for the generalists at the time of the COVID-19 pandemic
        date: 2020-07-17
       words: 657
      flesch: 38
     summary: results from the SPILI III study Towards evidenceinformed integration of public health and primary health care: experiences from Crete. The extend of the COVID-19 pandemic has decidedly demonstrated that the only way to monitor the pandemic effectively is to optimise the integration of public health and primary care.
    keywords: care; covid-19; health
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        item: #845 of 7819
          id: cord-257099-8k28vkgf
      author: Fan, Jingchun
       title: The epidemiology of reverse transmission of COVID-19 in Gansu Province, China
        date: 2020-05-12
       words: 2548
      flesch: 50
     summary: All confirmed COVID-19 cases amongst the returnees were displayed by the spatial distribution pattern of the extent of COVID-19 infection. To provide support to Chinese citizens who are currently overseas in 96 significant COVID-19 outbreak regions, to minimize their risk of COVID-19 infection, the Chinese 97 government has sent charter planes to evacuate Chinese citizens from a number of 98 COVID-19-affected countries, particularly Italy
    keywords: china; covid-19; infection; iran; province; returnees
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        item: #846 of 7819
          id: cord-257102-5i0zxhs1
      author: Abraham, Leola A.
       title: How COVID-19’s Disruption of the U.S. Correctional System Provides an Opportunity for Decarceration
        date: 2020-06-19
       words: 5276
      flesch: 37
     summary: However, significantly, PATTERN was not developed for the purpose of assessing eligibility for release during a public health crisis, but rather to assess the recidivism risk of BOP inmates. In a March 12, 2020 letter to Attorney General Barr, House Judiciary Committee Chairman Jerrold Nadler (D-NY) requested information on DOJ's handling of COVID-19 and the health and safety of those in federal prisons (Nadler 2020) .
    keywords: bop; confinement; covid-19; federal; home; inmates; prisons; release; risk; system; u.s; virus
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        item: #847 of 7819
          id: cord-257142-q79yy6o5
      author: Wambier, Carlos Gustavo
       title: Androgen sensitivity gateway to COVID‐19 disease severity
        date: 2020-05-15
       words: 3202
      flesch: 36
     summary: F I G U R E 2 Proposal of host vulnerability stratification following the androgen-driven COVID-19 hypothesis, subjects with increased androgen receptor activity through androgen receptor gene polymorphism or through hyperactivation by androgen hormones would be predisposed to increased viral infectivity and cumulative viral load, which would reflect on pronounced symptoms and transmissibility from cell lining of the airways and digestive tract. Additionally, there are many medical conditions that could increase androgen activity in females and might correlate with increasing vulnerability to COVID-19.
    keywords: androgen; covid-19; disease; patients; receptor; sars; tmprss2
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        item: #848 of 7819
          id: cord-257144-3q0un5rl
      author: Giri, Allan
       title: Mutagenic, Genotoxic and Immunomodulatory effects of Hydroxychloroquine and Chloroquine: a review to evaluate its potential to use as a prophylactic drug against COVID-19
        date: 2020-09-02
       words: 5582
      flesch: 41
     summary: Previously, we have evaluated the genetic toxicology of different drugs and chemicals including antimalarial drug CQ both in vitro and in vivo. The role of chloroquine supplementation in liquid holding recovery and ultraviolet lethality of Escherichia coli strains The comparative responses of Salmonella typhimurium TA1537 and TA97A to a range of reference mutagens and novel compounds Testing of chloroquine and quinacnne for mutagenicity in Drosophila melanogaster Comparison of the Ames assay and the induction of sister chromatid exchanges: results with ten pharmaceuticals and five selected agents Aspects of chloroquine mutagenicity Frameshift mutagenesis by chloroquine in Escherichia coli and Salmonella typhimurium Cortinas de Nava C. influence of the Uvr repair system on the mutagenicity of antiparasitic drugs Genetic toxicology testing of the antimalarial drugs Chloroquine and a new analog, AQ-13 Study of the evaluation of mutagenic effects of antimalarial drug chloroquine in Ames Salmonella assay Choloroquine inhibition of repair of DNA damage induced in mammalian cells by methyl methanesulfonate Cytogenetic effects of chloroquine in human lymphocyte cultures Simultaneous detection of chromosomal aberrations and sister-chromatid exchanges: experience with DNA intercalating agents Putative identification of functional interactions between DNA intercalating agents and topoisomerase II using the V79 in vitro micronucleus assay Anti-malarial chloroquine stimulate p53-apoptotic pathway in rat hepatocytes Genotoxicity of chloroquine in rat liver cells: protective role of free radical scavengers Action of chloroquine phosphate in rheumatoid arthritis.
    keywords: activation; cells; chloroquine; covid-19; drugs; effects; genotoxic; hcq; hydroxychloroquine; prophylactic; vitro; vivo
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        item: #849 of 7819
          id: cord-257158-obskf44d
      author: Assefa, K. T.
       title: The impact of COVID-19 infection on maternal and reproductive health care services in governmental health institutions of Dessie town, North-East Ethiopia, 2020 G.C.
        date: 2020-09-23
       words: 5132
      flesch: 52
     summary: preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in A 27-year-old lady also said that ' I fear to go to health institutions to get reproductive health care services because I think the health institutions is full of corona. The difference might be justified that the quality of health care was better in Nepal (the supply of medical equipment's that help to prevent COVID-19 in Ethiopia was low [24] .
    keywords: care; covid-19; health; institutions; maternal; providers; services; study; women
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        item: #850 of 7819
          id: cord-257160-40tdt7y3
      author: Gupta, Rohit
       title: Letter to the editor in response to COVID-19 presenting as acute pancreatitis
        date: 2020-07-01
       words: 826
      flesch: 26
     summary: None of the authors have any conflicts to declare We read with great interest the case report by Aloysius et al 1 describing development of acute pancreatitis in an obese female patient with COVID 19 infection. The diagnosis of acute pancreatitis was based on modified Atlanta criteria 2 which requires presence of two of the following three features: (1) abdominal pain consistent with acute pancreatitis (acute onset of a persistent, severe, epigastric pain often radiating to the back); (2) serum lipase activity (or amylase activity) at least three times greater than the upper limit of normal; and (3) characteristic findings of acute pancreatitis on contrast-enhanced computed tomography (CECT) and less commonly magnetic resonance imaging (MRI) or trans-abdominal ultrasonography.
    keywords: pancreatitis; patients
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        item: #851 of 7819
          id: cord-257161-lx3ar43e
      author: Yang, Xu
       title: Learner behaviors in synchronous online prosthodontic education during the 2020 COVID-19 pandemic
        date: 2020-10-03
       words: 2708
      flesch: 47
     summary: Additional studies about the effect of synchronous online education courses on learner theoretical knowledge and practical skills, in China and worldwide, are necessary. 8 Dentists are willing to conduct synchronous online dental continuing education courses, indicating that this educational model may be broadly adopted in the future.
    keywords: classroom; completion; covid-19; education; learning
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        item: #852 of 7819
          id: cord-257191-u5xnmsv8
      author: Farshi, Esmaeil
       title: Investigation of immune cells on elimination of pulmonary‐Infected COVID‐19 and important role of innate immunity, phagocytes
        date: 2020-09-18
       words: 2543
      flesch: 45
     summary: A mouse-adapted SARScoronavirus causes disease and mortality in BALB/c mice Mouse-passaged severe acute respiratory syndrome-associated coronavirus leads to lethal pulmonary edema and diffuse alveolar damage in adult but not young mice T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice Cellular immune responses to severe acute respiratory syndrome coronavirus (SARS-CoV) infection in senescent BALB/c mice: CD4+ T cells are important in control of SARS-CoV infection Phagocytic cells contribute to the antibody-mediated elimination of pulmonary-infected SARS coronavirus Selective long-term elimination of natural killer cells in vivo by an anti-interleukin 2 receptor beta chain monoclonal antibody in mice Lung pathology of fatal severe acute respiratory syndrome Alveolar macrophages are a major determinant of early responses to viral lung infection but do not influence subsequent disease development Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019 Clinical features of patients infected with 2019 novel coronavirus in Wuhan Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Functional exhaustion of antiviral lymphocytes in COVID-19 patients Antibody responses to SARS-CoV-2 in patients with COVID-19 How to cite this article: Farshi E, Kasmapur B, Arad A. Investigation of immune cells on elimination of pulmonary-Infected COVID-19 and important role of innate immunity, phagocytes key: cord-257191-u5xnmsv8 authors: Farshi, Esmaeil; Kasmapur, Bahram; Arad, Anya title: Investigation of immune cells on elimination of pulmonary‐Infected COVID‐19 and important role of innate immunity, phagocytes date: 2020-09-18 journal: Rev Med Virol DOI: 10.1002/rmv.2158 sha: doc_id: 257191 cord_uid: u5xnmsv8 We identified types of immune cells that contribute to clearing COVID‐19 during the acute phase of the infection in mouse model and human.
    keywords: cells; covid-19; infection; mice; patients; sars
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        item: #853 of 7819
          id: cord-257214-cje7sey1
      author: Pranata, Raymond
       title: Out-of-hospital cardiac arrest prognosis during the COVID-19 pandemic
        date: 2020-07-09
       words: 929
      flesch: 39
     summary: (Fig. 1) There are several explanations for increased OHCAassociated mortality during the pandemic; the first is due to increased unwitnessed cardiac arrest, as shown in the metaanalysis. The inclusion criteria were studies that compared OHCA in 2020 to previous years and reported any of the following: (1) proportion of out-of-hospital mortality, (2) proportion of unwitnessed cardiac arrest, (3) proportion of bystander CPR, or (4) proportion of shockable rhythm.
    keywords: arrest; covid-19; hospital
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        item: #854 of 7819
          id: cord-257258-hu9oxea1
      author: Chabner, Bruce A.
       title: Taking the Longer View of COVID‐19
        date: 2020-04-27
       words: 1812
      flesch: 35
     summary: While vaccine development has an obvious high priority, much attention has also been given in the press and in discussions of the White House Task Force to the development of effective antiviral drugs. COVID-19 vaccine frontrunners.
    keywords: covid-19; infection; patients; sars; trials; vaccine
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        item: #855 of 7819
          id: cord-257263-906epvo1
      author: Martellucci, Cecilia Acuti
       title: Changes in the spatial distribution of COVID-19 incidence in Italy using GIS-based maps
        date: 2020-07-18
       words: 1545
      flesch: 52
     summary: Italy reached the top of countries with the highest number of reported COVID-19 cases, now is the ninth country in cumulated cases. On March 15, 2020, most of the southern regions were not affected (Fig. 1) , but approximately a month later, all of them reported COVID-19 cases (Fig. 1) , including the insular regions of Sicily and Sardinia.
    keywords: cases; country; covid-19; italy; regions
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        item: #856 of 7819
          id: cord-257268-6a6nc2k7
      author: Kennelly, S. P.
       title: Asymptomatic carriage rates and case-fatality of SARS-CoV-2 infection in residents and staff in Irish nursing homes
        date: 2020-06-12
       words: 3586
      flesch: 55
     summary: Policies on testing and reporting of COVID-19 cases in NHs differ between countries but deaths in care home residents have accounted for 24-82% of all COVID-19-related deaths [1] . During the study period, 675 NH staff across twenty-four sites (85.7%; 24/28) (21 outbreak and 3 sites with ≤2 staff affected) had confirmed/suspected COVID-19 infection.
    keywords: covid-19; license; nhs; preprint; residents; staff
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        item: #857 of 7819
          id: cord-257273-itefsyv4
      author: Jefsen, O. H.
       title: COVID‐19‐related self‐harm and suicidality among individuals with mental disorders
        date: 2020-07-30
       words: 832
      flesch: 41
     summary: In their recent paper in Acta Psychiatrica Scandinavica, Madsen et al. describe how the COVID-19 pandemic may affect mental health and psychiatric care, and predict that suicide rates may increase because of the pandemic. 3 Should Madsen et al. be right in their dire prediction, we may expect to see a rise in self-harm and suicidality among individuals with mental disorders as one of the first manifestations.
    keywords: covid-19; pandemic
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        item: #858 of 7819
          id: cord-257274-fzyamd7v
      author: Peiro-Garcia, Alejandro
       title: How the COVID-19 pandemic is affecting paediatric orthopaedics practice: a preliminary report
        date: 2020-06-01
       words: 3907
      flesch: 46
     summary: As the COVID-19 pandemic has interfered in our daily practice, we have found a decrease in the number of paediatric trauma patients admitted to our ED, the number of patients visiting onsite to our paediatric orthopaedic clinic and the number of elective cases compared with other years. In the same vein, despite our hospital being a university hospital and receiving residents and fellows from other hospitals, these were required by law to return to their home hospitals to assist with COVID-19 patients.
    keywords: cases; children; covid-19; number; orthopaedic; pandemic; patients; practice
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        item: #859 of 7819
          id: cord-257309-sazs5wgh
      author: Ho, Hsi-en
       title: Clinical Outcomes and Features of Covid-19 in Patients with Primary Immunodeficiencies in New York City
        date: 2020-10-08
       words: 1344
      flesch: 41
     summary: Main Text: Coronavirus disease 2019 (Covid-19) remains an ongoing pandemic, and data on the clinical impact of SARS-CoV-2 infection in patients with primary immunodeficiency diseases (PIDs) are limited (1) (2) (3) . Here, we report the clinical features and outcomes of Covid-19 in patients from a large PID center in New York City during this period.
    keywords: cells; covid-19; patients; pid
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        item: #860 of 7819
          id: cord-257312-z6rmd0sg
      author: Dörr, Rolf
       title: Protecting patients and healthcare personnel from COVID-19: considerations for practice and outpatient care in cardiology
        date: 2020-04-16
       words: 665
      flesch: 44
     summary: Consider a lung CT scan as firstline testing method in patients with acute dyspnea and elevated body temperature In patients with acute dyspnea of unknown origin and elevated body temperature, a lung CT scan may be considered for confirmation of COVID-19.
    keywords: covid-19; patients
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        item: #861 of 7819
          id: cord-257344-d13at1y5
      author: Ghasemiyeh, Parisa
       title: COVID-19 Outbreak: Challenges in Pharmacotherapy Based on Pharmacokinetic and Pharmacodynamic Aspects of Drug Therapy in Patients with Moderate to Severe Infection
        date: 2020-09-18
       words: 5690
      flesch: 35
     summary: According to recently published researches, the most common clinical presentations in COVID-19 patients were fever in 83% to 98% of patients, dry cough in 76 to 82%, and fatigue or myalgia in 11 to 44% of them. So close patient monitoring is required in COVID-19 patients with pre-existing cardiovascular disease who are planned to treat with lopinavir/ritonavir and sometimes alternative drugs might be considered 52 .
    keywords: antiviral; chloroquine; coronavirus; covid-19; disease; drug; hydroxychloroquine; lopinavir; patients; potential; ribavirin; ritonavir; treatment
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        item: #862 of 7819
          id: cord-257357-u1npw7tw
      author: Lagunas‐Rangel, Francisco Alejandro
       title: Neutrophil‐to‐lymphocyte ratio and lymphocyte‐to‐C‐reactive protein ratio in patients with severe coronavirus disease 2019 (COVID‐19): A meta‐analysis
        date: 2020-04-08
       words: 424
      flesch: 24
     summary: key: cord-257357-u1npw7tw authors: Lagunas‐Rangel, Francisco Alejandro title: Neutrophil‐to‐lymphocyte ratio and lymphocyte‐to‐C‐reactive protein ratio in patients with severe coronavirus disease 2019 (COVID‐19): A meta‐analysis date: 2020-04-08 journal: J Med Virol DOI: 10.1002/jmv.25819 sha: doc_id: 257357 cord_uid: u1npw7tw Since March 11, 2020, the World Health Organization (WHO) defined Coronavirus disease 2019 (COVID-19) as a pandemic, with a series of confirmed cases that currently exceeded 300,000 people worldwide and with approximately 14,500 deaths. Neutrophil-to-lymphocyte ratio and lymphocyte-to-C-reactive protein ratio in patients with severe coronavirus disease 2019 (COVID-19): A meta-analysis Despite several reports describing increased levels of neutrophils and C-reactive protein along with a decrease in lymphocyte numbers in patients with COVID-19, 2,6-10 until now, very few reports have considered the cost-effective markers NLR and LCR to aid complication predictions.
    keywords: covid-19; patients
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        item: #863 of 7819
          id: cord-257361-7q0vbvvd
      author: Lee, James S.
       title: Critical care for COVID-19 during a humanitarian crisis—lessons learnt from Yemen
        date: 2020-09-23
       words: 1297
      flesch: 47
     summary: Invasive mechanical ventilation (IMV) received global attention but is only the visible tip of the iceberg for COVID-19 care. Routine ICU care, such as ventilator settings, ventilator-associated pneumonia prevention bundles, infusion pump usage, and early mobility, amongst others, were unfamiliar.
    keywords: care; icu; oxygen; patients
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        item: #864 of 7819
          id: cord-257374-8js7f9a3
      author: Watson, A.
       title: COVID-19 in Youth Soccer
        date: 2020-09-27
       words: 3732
      flesch: 45
     summary: Youth soccer clubs universally report implementing a number of risk reduction procedures. The comparison of COVID-19 within youth soccer clubs and national pediatric data is shown in Table 1 .
    keywords: covid-19; incidence; license; preprint; soccer
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        item: #865 of 7819
          id: cord-257408-ejhhk1iu
      author: Goss, Matthew B.
       title: The Pediatric Solid Organ Transplant Experience with COVID‐19: An Initial Multi‐Center, Multi‐Organ Case Series
        date: 2020-09-18
       words: 2295
      flesch: 39
     summary: As our patients presented with mild symptoms and most recovered within days, and less than half had evaluation of serum inflammatory biomarkers, we are unable to determine the meaning and role of assessment of inflammatory biomarkers in pediatric transplant patients. It will be critical to learn from and share our experience through the post-COVID-19 diagnosis and recovery period, with a focus on antibody kinetics and risk for re-infection, as we seek to understand the potential longterm effects of COVID-19 infection in immunosuppressed pediatric transplant patients.
    keywords: covid-19; patients; pediatric; recipients; symptoms; transplant
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        item: #866 of 7819
          id: cord-257429-k1rgljmu
      author: Daga, S.
       title: Employing a Systematic Approach to Biobanking and Analyzing Genetic and Clinical Data for Advancing COVID-19 Research
        date: 2020-07-24
       words: 6333
      flesch: 40
     summary: The GEN-COVID Multicenter Study was designed to collect and systematize biological samples and clinical data across multiple hospitals and health facilities in Italy with the purpose of deriving patient-level phenotypic and genotypic data and the specific intention to make samples and data available to COVID-19 researchers globally. Although patient care is the first priority, in the public health emergency situation brought on by the COVID-19 pandemic, it is also of the utmost importance to collect, process, and share with rapidity and confidence human biological materials, clinical data,, and study outcomes.
    keywords: author; copyright; covid-19; data; funder; holder; july; license; medrxiv; medrxiv preprint; perpetuity; preprint; version
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        item: #867 of 7819
          id: cord-257447-lwz5k0r8
      author: Whitehead, Brenda R
       title: COVID-19 as a Stressor: Pandemic Expectations, Perceived Stress, and Negative Affect in Older Adults
        date: 2020-09-04
       words: 3154
      flesch: 44
     summary: The 3 items used to assess pandemic expectations were developed by the researcher based on discrepant opinions on the impact and duration of the pandemic event at the time of data collection (i.e., some perceiving it as a minor passing annoyance, others perceiving it as a long-term, high-impact event). Findings provide evidence that expectations about a pandemic influence the extent to which older adults experience stress and NA in the midst of a pandemic event.
    keywords: p t; pandemic; stress
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        item: #868 of 7819
          id: cord-257468-woyycghi
      author: Basso, Trude
       title: Transmission of infection from non-isolated patients with COVID-19 to health care workers
        date: 2020-08-20
       words: 1828
      flesch: 52
     summary: These results were in accordance with other reports and should reassure HCWs and further stimulate a broader evaluation of the foundation for the current practice of home-quarantine of non-symptomatic HCWs. Our results should reassure HCWs and further stimulate a broader evaluation of the foundation for the current practice of home-quarantine of non-symptomatic HCWs.
    keywords: cov-2; covid-19; hcws; patient; sars
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        item: #869 of 7819
          id: cord-257555-tmuvbq1k
      author: Munsch, N.
       title: A benchmark of online COVID-19 symptom checkers
        date: 2020-05-26
       words: 3639
      flesch: 54
     summary: To our knowledge this is the first scientific evaluation of online COVID-19 symptom checkers, however, there are a number of related studies evaluating symptom checkers. To our knowledge, no study has evaluated the accuracy of COVID-19 symptom checkers in a statistically rigorous manner.
    keywords: covid-19; license; medrxiv; preprint; symptom
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        item: #870 of 7819
          id: cord-257556-lmws8eed
      author: Rafiq, Danish
       title: Three months of COVID‐19: A systematic review and meta‐analysis
        date: 2020-05-18
       words: 3208
      flesch: 39
     summary: Phylogeny of SARS-Like Betacoronaviruses Including Novel Coronavirus (nCoV A pneumonia outbreak associated with a new coronavirus of probable bat origin Angiotensinconverting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A joint research team of the Shanghai Institute of Materia Medica and Shanghai Tech University discover a group of old and traditional Chinese medicines that may be efficacious in treating the novel form of pneumonia Accelerated Emergency Use Authorization (Eua) Summary Covid-19 Rapid tests for influenza, respiratory syncytial virus, and other respiratory viruses: a systematic review and meta-analysis Diagnostic indexes of a rapid IgG/IgM combined antibody test for SARS-CoV-2 Evaluation of recombinant nucleocapsid and spice protein serological diagnosis of novel coronavirus disease 2019 (COVID-19) Serological immunochromatographic approach in diagnosis with SARS-CoV-2 infected COVID-19 patients Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis A mathematical model for simulating the transmission of Wuhan novel coronavirus Report 2: estimating the potential Total number of novel coronavirus cases in Wuhan City A family of embedded Runge-Kutta formulae Estimating the Unreported Number of Novel Coronavirus (2019-nCoV) Cases in China in the First Half of January 2020: a data-driven Modelling analysis of the early outbreak Estimation of the transmission risk of the 2019-nCoV and its implication for public health interventions An updated estimation of the risk of transmission of the novel coronavirus The reproductive number of COVID-19 is higher compared to SARS coronavirus Epidemic analysis of COVID-19 in China by dynamical modeling Estimation of the reproductive number of novel coronavirus (COVID-19) and the probable outbreak size on the diamond princess cruise ship: a data-driven analysis A mathematical model for simulating the phase-based transmissibility of a novel coronavirus Insights from early mathematical models of 2019-nCoV acute respiratory disease (COVID-19) dynamics Preliminary prediction of the basic reproduction number of the Wuhan novel coronavirus 2019-nCoV A conceptual model for the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China with individual reaction and governmental action Data-based analysis, Modelling and forecasting of the COVID-19 outbreak Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Modelling the epidemic trend of the 2019 novel coronavirus outbreak in China Transmission dynamics of 2019 novel coronavirus (2019-nCoV)
    keywords: china; coronavirus; cov-2; covid-19; novel; outbreak; patients; sars; transmission
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        item: #871 of 7819
          id: cord-257566-56h2jmn9
      author: Zamboni, Paolo
       title: COVID-19 as a Vascular Disease: Lesson Learned from Imaging and Blood Biomarkers
        date: 2020-06-29
       words: 5584
      flesch: 40
     summary: From the outset, it became mandatory to identify and isolate COVID-19 patients, many of whom were then admitted to hospital. The addition of systemic proinflammatory cytokines release as a consequence of endothelial inflammation, as well as the expression of the ACE2 receptors for SARS-CoV-2 on the membrane of the vascular muscle and endothelial cells, may help to explain why COVID-19 patients are also susceptible to arterial thrombosis, even in young non-arteriosclerotic individuals [25] .
    keywords: covid-19; dimer; disease; levels; lus; patients; pneumonia; troponin; ultrasound
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        item: #872 of 7819
          id: cord-257600-0plhquk9
      author: Calles, Antonio
       title: Outcomes of COVID-19 in Patients With Lung Cancer Treated in a Tertiary Hospital in Madrid
        date: 2020-09-16
       words: 6983
      flesch: 43
     summary: We aimed to analyze outcomes of lung cancer patients affected by COVID-19 in a tertiary hospital of a high-incidence region during the pandemic. Conclusions: Lung cancer patients represent a vulnerable population for COVID-19, according to the high rate of hospitalization, onset of ARDS, and high mortality rate.
    keywords: cancer; cancer patients; cases; cov-2; covid-19; lung; lung cancer; mortality; patients; sars; therapy; treatment
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        item: #873 of 7819
          id: cord-257603-ov0b8yub
      author: Azlan, Arina Anis
       title: Public knowledge, attitudes and practices towards COVID-19: A cross-sectional study in Malaysia
        date: 2020-05-21
       words: 4686
      flesch: 50
     summary: Even so, correct rates of COVID-19 knowledge ranged widely indicating that while some participants had high levels of knowledge on the disease, others did not. Several studies conducted in other Asian countries have indicated high levels of COVID-19 knowledge among the general population [13] and healthcare workers
    keywords: attitudes; covid-19; health; knowledge; malaysia; mco; participants; practices; survey
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        item: #874 of 7819
          id: cord-257611-z0sng9sx
      author: Kalantari, Hamidreza
       title: Determination of COVID-19 prevalence with regards to age range of patients referring to the hospitals located in western Tehran, Iran
        date: 2020-10-07
       words: 2801
      flesch: 54
     summary: The highest rate of recovery (65.2%) in COVID-19 patients was observed in those within the age range of 30-39 years and overall, a high rate of recovery was indicated (Table 1 and 2). In this descriptive-cross-sectional study, a total of 784 samples of naso/oropharyngeal swabs of suspected patients with COVID-19 symptoms who had referred to Imam Khomeini, Shahid Fayaz-Bakhsh and Modarres hospitals in Tehran from February 24, 2020 to March 24, 2020 were examined by RT-PCR method.
    keywords: age; covid-19; mortality; patients; rate; years
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        item: #875 of 7819
          id: cord-257613-o0q7hvn3
      author: Shafiee, Abbas
       title: Coronavirus disease 2019: A tissue engineering and regenerative medicine perspective
        date: 2020-08-21
       words: 3434
      flesch: 33
     summary: Over the COVID-19 outbreak, the funding for many TERM projects is being cut, which has a significant impact on the present and future of Current clinical trials highlight the potential benefits of stem cell therapies for COVID-19 patients. Effective multi-institutional collaboration and adequate funding from government and nongovernment sources are also needed to collect and analyze the data from ongoing and new human trials, to better understand the potential benefits of stem cell therapies for COVID-19 patients.
    keywords: acute; cells; covid-19; mesenchymal; mscs; stem; syndrome; therapies; tissue; treatment
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        item: #876 of 7819
          id: cord-257707-brrrg4fr
      author: Jayasighe, Ravindri
       title: Quality of online information for the general public on COVID-19
        date: 2020-08-07
       words: 2132
      flesch: 47
     summary: So far only a limited number of studies have been done to assess the quality of health information websites related to COVID-19. Although, high quality health information is known to be related to lower stress levels and better psychological health [5] , previous studies have shown that online information on many medical disorders to be of substandard quality
    keywords: covid-19; health; information; quality; websites
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        item: #877 of 7819
          id: cord-257717-fbfe5vt4
      author: Wallis, Christopher J.D.
       title: The Impact of the COVID-19 Pandemic on Genitourinary Cancer Care: Re-envisioning the Future
        date: 2020-09-04
       words: 7915
      flesch: 31
     summary: Overall, the goal is to treat cancer patients with as close to standard therapies as possible once the risk/ benefit ratio has been considered. For cancer patients, including those within bench research, clinical trials, observational studies, realworld effectiveness of agents, and randomised trials, support is derived from research staff and well-being from knowledge that you are helping other patients [110] .
    keywords: approach; bladder; cancer; care; covid-19; health; hospital; impact; outcomes; pandemic; patients; prostate; research; risk; surveillance; telemedicine; treatment; trial
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        item: #878 of 7819
          id: cord-257718-72b0edg6
      author: Romanelli, John
       title: The COVID-19 reset: lessons from the pandemic on Burnout and the Practice of Surgery
        date: 2020-10-13
       words: 4666
      flesch: 44
     summary: The surgeon and author Atul Gawande made valid comments about EMR systems and their impact on physician and surgeon wellness in his essay published in The New Yorker. SAGES examined concerns about surgeon wellness during the pandemic [9] .
    keywords: burnout; care; joy; life; meaning; pandemic; purpose; surgeons; surgical; wellness; work
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        item: #879 of 7819
          id: cord-257729-s0vo7dlk
      author: Bauer, Melissa
       title: Obstetric Anesthesia During the Coronavirus Disease 2019 Pandemic
        date: 2020-04-20
       words: 4289
      flesch: 28
     summary: In principle, the clinical characteristics reported in pregnant women with confirmed COVID-19 infection in China have been consistent with those reported among nonpregnant adults, with better maternal and neonatal outcomes with COVID-19 infection compared with the 2002-2003 severe acute respiratory syndrome (SARS) outbreak from SARS CoV 1 infection. It is imperative to establish a back-up team to care for patients without COVID-19 infection due to the time-intensive tasks of donning/doffing PPE, transporting the patient, providing anesthetic care, and performing surgery in patients with active COVID-19 infection.
    keywords: anesthesia; care; cesarean; coronavirus; covid-19; delivery; infection; labor; patients; women
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        item: #880 of 7819
          id: cord-257732-3xuy6tbn
      author: Azzi, Lorenzo
       title: Saliva is a reliable tool to detect SARS-CoV-2
        date: 2020-04-14
       words: 3516
      flesch: 48
     summary: This study analyzed salivary samples of COVID-19 patients and compared the results with their clinical and laboratory data. Indeed, LDH is commonly released during tissue damage, it can be associated to the lung damage that takes place in COVID-19 patients.
    keywords: cov-2; covid-19; patients; saliva; salivary; sars; values
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        item: #881 of 7819
          id: cord-257746-pqom76hk
      author: Franic, Tomislav
       title: Covid-19, child and adolescent mental health – Croatian (in)experience
        date: 2020-05-21
       words: 2397
      flesch: 54
     summary: Care is free of charge as it is for adult mental health patients. key: cord-257746-pqom76hk authors: Franic, Tomislav; Dodig-Curkovic, Katarina title: Covid-19, child and adolescent mental health – Croatian (in)experience date: 2020-05-21 journal: Irish journal of psychological medicine DOI: 10.1017/ipm.2020.55 sha: doc_id: 257746 cord_uid: pqom76hk The Covid-19 pandemic has caused unseen socio-economic changes all over the world, where enormous efforts are being made to preserve lives and maintain functional health systems.
    keywords: camh; covid-19; croatia; health; pandemic; services
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        item: #882 of 7819
          id: cord-257751-n7w1psr4
      author: Halperin, Daniel T.
       title: Coping With COVID-19: Learning From Past Pandemics to Avoid Pitfalls and Panic
        date: 2020-06-30
       words: 6384
      flesch: 50
     summary: [47] [48] Because young people typically come in contact with many other children and adults, they are often efficient spreaders of respiratory pathogens. Most of those who do drive or go outdoors use masks (needlessly) even when far away from other people.
    keywords: cases; children; coronavirus; countries; covid-19; deaths; health; new; pandemic; people; risk; schools; states; transmission
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        item: #883 of 7819
          id: cord-257765-ljt9rn8z
      author: Ghisolfi, Selene
       title: Predicted COVID-19 fatality rates based on age, sex, comorbidities and health system capacity
        date: 2020-09-09
       words: 3989
      flesch: 43
     summary: ► Using variation in demographics, comorbidities and health system capacity, we predict COVID-19 IFRs for 187 countries, ranging from 0.43% in Western Sub-Saharan Africa to 1.45% in Eastern Europe. However, the wide gap in childhood respiratory tract IFRs of between 2.8-fold and 7.4-fold between income groups has implications for COVID-19 IFRs that are too large to ignore.
    keywords: age; countries; covid-19; estimates; health; ifrs; income; sex
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        item: #884 of 7819
          id: cord-257766-z7vcdtcq
      author: Varadhachary, Atul
       title: Salivary anti-SARS-CoV-2 IgA as an accessible biomarker of mucosal immunity against COVID-19
        date: 2020-08-11
       words: 8483
      flesch: 45
     summary: Increasing concentrations of commercially available anti-S1 and anti-NP IgA antibodies were spiked into simulated saliva in order to mimic COVID-19 patient samples. https://doi.org/10.1101/2020.08.07.20170258 doi: medRxiv preprint True negative (pre-COVID, acquired prior to December 2019) patient saliva samples were sourced from a commercial vendor and assessed using the BRAVO assay.
    keywords: antibodies; collection; cov-2; covid-19; iga; immune; immunity; license; medrxiv; medrxiv preprint; mucosal; preprint; salivary; samples; sars
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        item: #885 of 7819
          id: cord-257781-ybpliz32
      author: Jones, Eben
       title: Subcutaneous Emphysema, Pneumomediastinum, and Pneumothorax in Critically Ill Patients With Coronavirus Disease 2019: A Retrospective Cohort Study
        date: 2020-09-17
       words: 3478
      flesch: 39
     summary: The median duration of illness prior to critical care admission was 3 days longer in barotrauma patients (10 vs 7 d; IQR 8-14 and 6-10, respectively; p = 0.073). Second, barotrauma patients also tended to have a longer disease course prior to critical care admission.
    keywords: barotrauma; care; covid-19; median; patients; pressure; support; ventilation
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        item: #886 of 7819
          id: cord-257789-pdybfft6
      author: Diamond, Betty
       title: SARS-CoV-2 and interferon blockade
        date: 2020-11-09
       words: 3596
      flesch: 30
     summary: In the case of a virus like SARS-CoV-2 which is transmitted by inhalation, the virus most likely enters through olfactory bulb epithelial cells (Bilinska et al. 2020) , and then enters ACE2 expressing microglia and neurons (Xu et al. 2005; Jaunmuktane et al. 2020; Ellul et al. 2020) , although other recent studies suggest that non-neuronal cell types play a role in the development of anosmic symptoms (Bilinska et al. 2020; Brann et al. 2020 ). As ACE2 is the main viral entry receptor, ACE2 receptor antagonists based on peptides from the viral spike protein are being synthesized and tested, in addition to spike protein-targeted antagonists derived from critical binding regions in the ACE2 receptor (VanPatten et al. 2020) .
    keywords: ace2; angiotensin; bradykinin; cov-2; covid-19; inflammation; interferon; sars
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        item: #887 of 7819
          id: cord-257806-jcc7ljcm
      author: Yao, Jasper Seth
       title: Covid-19 in dementia: an insidious pandemic
        date: 2020-06-25
       words: 205
      flesch: 35
     summary: While in large cohorts, fever and cough are the most common presenting symptoms among Covid-19 patients, 1 our findings show that dyspnea and altered mental status may manifest as the prominent symptoms of Covid-19 among patients of older age with dementia. Predisposition towards delirium may increase the risk of further cognitive impairment.
    keywords: covid-19
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        item: #888 of 7819
          id: cord-257814-h7n4nw4w
      author: Holm, Are M.
       title: Ethical Considerations regarding Heart and Lung Transplantation and Mechanical Circulatory Support during the COVID-19 Pandemic: An ISHLT COVID-19 Task Force Statement
        date: 2020-04-25
       words: 2221
      flesch: 36
     summary: A Framework for Rationing Ventilators and Critical Care Beds During the COVID-19 Pandemic Transplantation ethics Italian Society of Anesthesia A, Resuscitation and Intensive Care (Società Italiana di Clinical ethics recommendations for the allocation of intensive care treatments Saving those who can't wait INTERMACS profiles and outcomes of ambulatory advanced heart failure patients: A report from the REVIVAL Registry Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention How to handle scientific articles on organ transplantation coming from China in 2019? In summary, the estimation of survival benefit, with categorical emphasis on saving imminently threatened lives (Rule of Rescue) and the utilitarian estimation of expected survival, are the dominating factors for organ allocation in thoracic transplantation or MCS.
    keywords: covid-19; organ; pandemic; patients; transplant; transplantation
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        item: #889 of 7819
          id: cord-257824-qz6yxuph
      author: Fuertes, Víctor
       title: Current impact of Covid-19 pandemic on Spanish plastic surgery departments: a multi-center report
        date: 2020-05-19
       words: 3488
      flesch: 51
     summary: In two of the centers we have contacted, the staff has been properly trained on the medical management of Covid-19 patients. key: cord-257824-qz6yxuph authors: Fuertes, Víctor; Monclús, Enrique; Agulló, Alberto title: Current impact of Covid-19 pandemic on Spanish plastic surgery departments: a multi-center report date: 2020-05-19 journal: Eur J Plast Surg DOI: 10.1007/s00238-020-01686-0 sha: doc_id: 257824 cord_uid: qz6yxuph BACKGROUND: After its initial description in China, Covid-19 is hitting nations across the world, with Spain as the third country in number of deaths, after the USA and Italy.
    keywords: cases; covid-19; departments; hospital; pandemic; patients; surgery
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        item: #890 of 7819
          id: cord-257839-kfzc4pwq
      author: Ferguson, Katie
       title: COVID-19 associated with extensive pulmonary arterial, intracardiac and peripheral arterial thrombosis
        date: 2020-08-03
       words: 2809
      flesch: 43
     summary: Incidence of venous thromboembolism in hospitalized patients with COVID-19 Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in The British Thoracic Society. [1] [2] [3] [4] Expert guidance currently recommends higher than standard doses of prophylactic anticoagulation for patients with COVID-19 requiring critical care.
    keywords: arterial; case; covid-19; day; left; limb; patients; pulmonary
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        item: #891 of 7819
          id: cord-257867-3j6o1nko
      author: Romano, Nicola
       title: Pneumomediastinum related to Covid-19 pneumonia
        date: 2020-06-06
       words: 336
      flesch: 22
     summary: We herein report two cases of pneumomediastinum related to Covid-19 pneumonia, in patients who underwent chest-CT scan in our Hospital. Although pneumomediastinum is usually considered a self-limiting condition, with an unknown precise pathological mechanism, we wanted to describe this possible complication of Covid-19 pneumonia, that may be considered COVID-19 with spontaneous pneumomediastinum Mediastinal Emphysema, Giant Bulla, and Pneumothorax Developed during the Course of COVID-19 Pneumonia Spontaneous pneumomediastinum occurring in the SARS-COV-2 infection Spontaneous pneumomediastinum: 41 cases Molecular pathology of emerging coronavirus infections Figure 1
    keywords: pneumomediastinum
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        item: #892 of 7819
          id: cord-257870-b52k75m4
      author: Chen, Qianqian
       title: Carcinoembryonic Antigen: A Potential Biomarker to Evaluate the Severity and Prognosis of COVID-19
        date: 2020-10-06
       words: 3855
      flesch: 38
     summary: To our knowledge, only one study about the serum cancer biomarkers including CEA levels of COVID-19 patients have been published (19) . However, the role of CEA levels in clinical outcomes or CT involvements of COVID-19 patients was still unknown.
    keywords: analysis; cases; cea; covid-19; levels; lung; patients; severity; study
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        item: #893 of 7819
          id: cord-257884-5exwwxin
      author: Kumar, Rajesh
       title: Acute pericarditis as a primary presentation of COVID-19
        date: 2020-08-18
       words: 2112
      flesch: 51
     summary: [4] [5] [6] One reported COVID-19 case with upper respiratory tract symptoms had haemorrhagic pericardial effusion with tamponade. key: cord-257884-5exwwxin authors: Kumar, Rajesh; Kumar, Jathinder; Daly, Caroline; Edroos, Sadat Ali title: Acute pericarditis as a primary presentation of COVID-19 date: 2020-08-18 journal: BMJ Case Rep DOI: 10.1136/bcr-2020-237617 sha: doc_id: 257884 cord_uid: 5exwwxin The COVID-19 pandemic is a highly contagious viral illness which conventionally manifests primarily with respiratory symptoms.
    keywords: acute; cardiac; case; covid-19; pain; pericarditis
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        item: #894 of 7819
          id: cord-257889-zcxn5cx0
      author: Aledo‐Serrano, Ángel
       title: Genetic epilepsies and COVID‐19 pandemic: Lessons from the caregiver perspective
        date: 2020-05-18
       words: 1047
      flesch: 39
     summary: Although children appear to present milder COVID-19 manifestations, 4 patients with DEEs present an increased susceptibility to certain triggers related to viral infections and respiratory comorbidities, are at risk of missing medical follow-up and emergency assistance due to health care resource allocation focus on COVID-19 patients, and are exposed to broader sociopsychological impact related to lockdown. Because of the high rate of mild or asymptomatic cases in pediatric populations, we also asked whether there had been confirmed COVID-19 cases in people with close contact with the patient.
    keywords: covid-19; pandemic; patients
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        item: #895 of 7819
          id: cord-257933-qpf1tiod
      author: Liu, Chao
       title: The COVID-19 Outbreak Negatively Affects the Delivery of Care for Patients With Diabetic Foot Ulcers
        date: 2020-09-11
       words: 1050
      flesch: 50
     summary: During the outbreak, it is reasonable for patients to evaluate perceived risks and benefits before taking health-related actions, thus protracting the time lapse in seeking DFU care. A recent survey from Manchester, U.K., and Los Angeles, CA, revealed that more than half of patients were deterred from traditional face-toface appointments and those admitted from clinics for inpatient DFU care were candidates for surgical interventions (2) .
    keywords: care; covid-19; group; patients
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        item: #896 of 7819
          id: cord-257939-tgpsd3r7
      author: Haider, Maryam B.
       title: A 46-Year-Old Woman Who Presented with Diabetic Ketoacidosis and COVID-19 Pneumonia with Multiple Pulmonary Thromboemboli: A Case Report
        date: 2020-07-20
       words: 1502
      flesch: 42
     summary: It is suspected to be more prevalent in COVID-19 patients, especially those needing admission in the intensive care unit. The patient in discussion developed PE despite being on a prophylactic dose of heparin, suggesting that only a prophylactic dose may not be sufficient to prevent VTE in COVID-19 patients with higher inflammatory markers.
    keywords: covid-19; patients; vte
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        item: #897 of 7819
          id: cord-257944-a59ph9c5
      author: Rosa, Marcela Emer Egypto
       title: COVID-19 findings identified in chest computed tomography: a pictorial essay
        date: 2020-06-18
       words: 1568
      flesch: 42
     summary: key: cord-257944-a59ph9c5 authors: Rosa, Marcela Emer Egypto; de Matos, Marina Justi Rosa; Furtado, Renata Silveira Olimpio de Paula; Brito, Vanessa Mizubuti; Amaral, Lucas Tadashi Wada; Beraldo, Gabriel Laverdi; Fonseca, Eduardo Kaiser Ururahy Nunes; Chate, Rodrigo Caruso; Passos, Rodrigo Bastos Duarte; Teles, Gustavo Borges da Silva; Silva, Murilo Marques Almeida; Yokoo, Patrícia; Yanata, Elaine; Shoji, Hamilton; Szarf, Gilberto; Funari, Marcelo Buarque de Gusmão title: COVID-19 findings identified in chest computed tomography: a pictorial essay date: 2020-06-18 journal: (14, 15) Ground-ground-glass opacities are the most common and early finding (approximately zero to 4 days after onset of symptoms) in COVID-19 patients; they often present bilateral, peripheral and subpleural distribution in the lower lobes (Figures 1 and 2) .
    keywords: chest; covid-19; disease; findings; ground; patients
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        item: #898 of 7819
          id: cord-257958-yehnlabq
      author: Barh, Debmalya
       title: Multi-omics-based identification of SARS-CoV-2 infection biology and candidate drugs against COVID-19
        date: 2020-10-10
       words: 5439
      flesch: 35
     summary: [14] and DrugMatrix (a Comprehensive Toxicogenomic Database) for gene set analysis based candidate drug enrichment. gene set analysis toolkit with revamped UIs and APIs DrugBank: a comprehensive resource for in silico drug discovery and exploration NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis InnateDB: systems biology of innate immunity and beyond--recent updates and continuing curation KEGG: new perspectives on genomes, pathways, diseases and drugs PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools The AI-Discovered Aetiology of COVID-19 and Rationale of the Irinotecan+Etoposide Combination Therapy for Critically Ill COVID-19 Patients Vulnerabilities of the SARS-CoV-2 virus to proteotoxicityopportunity for repurposed chemotherapy of COVID-19 infection, bioRxiv SARS-CoV-2 (COVID-19) and Chronic Myeloid Leukemia (CML): a Case Report and Review of ABL Kinase Involvement in Viral Infection Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19, bioRxiv Silico Discovery of Candidate Drugs against Covid-19, Viruses Prediction of repurposed drugs for treating lung injury in COVID-19 Artificial intelligence approach fighting COVID-19 with repurposing drugs COVID-19: Drug Targets and Potential Treatments The serotonin reuptake inhibitor Fluoxetine inhibits SARS-CoV-2, bioRxiv Broad anti-coronaviral activity of FDA approved drugs against SARS-CoV-2 in vitro and SARS-CoV in vivo, bioRxiv Understanding SARS CoV 2 endocytosis for COVID 19 drug repurposing Indomethacin has a potent antiviral activity against SARS CoV-2 in vitro and canine coronavirus in vivo, bioRxiv Indomethacin and resveratrol as potential treatment adjuncts for SARS CoV 2/COVID 19 Identification of novel compounds against three targets of SARS CoV-2 coronavirus by combined virtual screening and supervised machine learning Repurposing drugs for COVID-19 based on transcriptional response of host cells to SARS-CoV-2, arXiv Andrographolide as a potential inhibitor of SARS-CoV-2 main protease: an in silico approach Apremilast as a potential treatment option for COVID 19: No symptoms of infection in a psoriatic patient Combination of thrombolytic and immunosuppressive therapy for coronavirus disease 2019:
    keywords: analysis; candidate; cov-2; covid-19; drugs; gene; infection; omics; pathways; potential; sars; set; table
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        item: #899 of 7819
          id: cord-257969-2tax8ajw
      author: Bhopal, Raj S.
       title: COVID-19 zugzwang: potential public health moves towards population (herd) immunity
        date: 2020-07-15
       words: 4251
      flesch: 48
     summary: To control an infection with an R of about 1 and even somewhat higher we need about 50% of the population to have immunity (unlike measles where over 90% is needed).(5, 6) Currently, the prevalence of COVID-19 infection is variably estimated from 1-20% according to locality and work settings. Until there is a vaccine, population immunity is going to occur only from infection.
    keywords: column; covid-19; health; immunity; infection; people; population; public; table
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        item: #900 of 7819
          id: cord-257995-kgmsecg3
      author: Vilallonga, Ramon
       title: Reply To The Article “Bariatric Surgical Practice During the Initial Phase of COVID-19 Outbreak.” by Aminian, A., Kermansaravi, M., Azizi, S. et al. Published in Obesity Surgery
        date: 2020-05-13
       words: 548
      flesch: 45
     summary: The patients included received different treatments that have already been described for COVID-19 pneumonia management, including hydroxychloroquine, antiretroviral (lopinavir and ritonavir), tocilizumab, and hemoperfusion. Moreover, there are several factors in which obesity can play a role in poor outcomes from COVID-19 infection.
    keywords: covid-19; patients
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        item: #901 of 7819
          id: cord-258011-19yfwvki
      author: Deprest, Jan
       title: SARS‐CoV2 (COVID‐19) infection: is fetal surgery in times of national disasters reasonable?
        date: 2020-04-22
       words: 2093
      flesch: 42
     summary: Along this line, it would seem logical in certain places to also suspend offering fetal procedures of large complexity given their potential requirements for maternal ICU beds and/or long-term maternal hospital admission. key: cord-258011-19yfwvki authors: Deprest, Jan; Van Ranst, Marc; Lannoo, Lore; Bredaki, Emma; Ryan, Greg; David, Anna; Richter, Jute; Van Mieghem, Tim title: SARS‐CoV2 (COVID‐19) infection: is fetal surgery in times of national disasters reasonable? date: 2020-04-22 journal:
    keywords: cov2; covid-19; patients; sars; women
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        item: #902 of 7819
          id: cord-258012-wzwowl4l
      author: Zhaori, Getu
       title: Smoke evacuation, is it important for prevention of COVID‐19?
        date: 2020-06-24
       words: 1084
      flesch: 45
     summary: key: cord-258012-wzwowl4l authors: Zhaori, Getu title: Smoke evacuation, is it important for prevention of COVID‐19? date: 2020-06-24 journal: Pediatr Investig DOI: 10.1002/ped4.12207 sha: doc_id: 258012 cord_uid: wzwowl4l nan wileyonlinelibrary.com/journal/ped4 The 2019 novel coronavirus pneumonia/disease outbreak/epidemic in China has been largely under control, but the pandemic of the disease is still ongoing in many parts of the world. A Method for smoke evacuation in laparoscopic surgeries for suspected coronavirus infected patients reported by Drs.
    keywords: evacuation; smoke; system
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        item: #903 of 7819
          id: cord-258018-29vtxz89
      author: Cooper, Ian
       title: A SIR model assumption for the spread of COVID-19 in different communities
        date: 2020-06-28
       words: 5817
      flesch: 52
     summary: The Lancet infectious diseases Modified SEIR and AI prediction of the epidemics trend of COVID-19 in China under public health interventions Analysis and forecast of COVID-19 spreading in China, Italy and France A data-driven network model for the emerging COVID-19 epidemics in Wuhan, Toronto and Italy Estimation of COVID-19 dynamics on a back-of-envelope: Does the simplest SIR model provide quantitative parameters and predictions Modeling the impact of mass influenza vaccination and public health interventions on COVID-19 epidemics with limited detection capability Three basic epidemiological models The mathematics of infectious diseases The basic epidemiology models: models, expressions for R0, parameter estimation, and applications The SIR model and the foundations of public health Global analysis of the COVID-19 pandemic using simple epidemiological models A modified sir model for the covid-19 contagion in Italy Mathematical modeling of covid-19 transmission dynamics with a case study of wuhan Mod-370 elling the COVID-19 epidemic and implementation of population-wide interventions in Italy The effectiveness of quarantine of Wuhan city against the Corona Virus Disease 2019 (COVID19): A wellmixed SEIR model analysis ), e0230405. System (1) can be solved numerically to find how the scaled (by f ) susceptible S, infected I and removed R m populations (what we call model solutions) evolve with time, in good agreement with the recorded data.
    keywords: covid-19; data; model; number; population; sir; sir model; susceptible
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        item: #904 of 7819
          id: cord-258019-njky7v5x
      author: Kinaret, Pia A.S.
       title: Covid-19 acute responses and possible long term consequences: What nanotoxicology can teach us
        date: 2020-08-10
       words: 1360
      flesch: 38
     summary: key: cord-258019-njky7v5x authors: Kinaret, Pia A.S.; Giudice, Giusy del; Greco, Dario title: Covid-19 acute responses and possible long term consequences: What nanotoxicology can teach us date: 2020-08-10 journal: Nano Today DOI: 10.1016/j.nantod.2020.100945 sha: doc_id: 258019 cord_uid: njky7v5x Long-term effects of Covid-19 disease are still poorly understood. Interestingly, initial evidence also points to an association between Covid-19 disease severity and exposure to particulate matter pollution.
    keywords: covid-19; exposure; fibrosis; nanomaterials; sars
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        item: #905 of 7819
          id: cord-258029-gyvg7ffa
      author: Moolasart, Visal
       title: Favipiravir-based regimen for coronavirus disease 2019 pneumonia for a 47-day-old male newborn
        date: 2020-10-15
       words: 1519
      flesch: 41
     summary: Novel coronavirus (2019-nCoV) situation reports Epidemiological characteristics and prevention and control measures of corona virus disease 2019 in children Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Anti-malaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal model Coronavirus disease (COVID-19) and neonate: what neonatologist need to know Clinical characteristics of children with coronavirus disease 2019 in Hubei, China A review of SARS-CoV-2 and the ongoing clinical trials Thailand ministry of public health. A 47-day-old, asymptomatic male newborn of coronavirus disease 2019 infected mother tested positive for coronavirus disease 2019 by reverse transcription polymerase chain reaction.
    keywords: coronavirus; covid-19; day; disease; favipiravir
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        item: #906 of 7819
          id: cord-258067-par61wwh
      author: Di Martino, Marcello
       title: Elective Surgery During the SARS-CoV-2 Pandemic (COVID-19): A Morbimortality Analysis and Recommendations on Patient Prioritisation and Security Measures
        date: 2020-06-20
       words: 3466
      flesch: 32
     summary: Therefore, when reporting the morbidity and mortality of surgical patients with the COVID-19 infection, the severity of complications will be indicated according to the Dindo-Clavien classification (19) ; the therapeutic measures used with each patient according to a classification of treatments required (as described in Table 1 ) and the severity of the respiratory infection according to the Brescia respiratory COVID-19 severity scale (BRCSS) (20) . A Retrospective Cohort Study in a Designated Hospital of Wuhan in China ASA classification and perioperative variables as predictors of postoperative outcome Predictive Factors of Pancreatic Fistula After Pancreaticoduodenectomy and External Validation of Predictive Scores Genetic And Morphological Evaluation (GAME) score for patients with colorectal liver metastases Predictive factors for anastomotic leakage after laparoscopic colorectal surgery Frailty and post-operative outcomes in older surgical patients: a systematic review AASLD guidelines for the treatment of hepatocellular carcinoma Systematic review and meta-analysis of local ablative therapies for resectable colorectal liver metastases Endoscopic resection techniques for colorectal neoplasia: Current developments A watch-and-wait approach for locally advanced rectal cancer after a clinical complete response following neoadjuvant chemoradiation: a systematic review and meta-analysis
    keywords: complications; covid-19; infection; pandemic; patients; sars; surgery
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        item: #907 of 7819
          id: cord-258072-6d5ieakl
      author: Kochhar, Anuraj Singh
       title: Lockdown of 1.3 Billion People In India During Covid-19 Pandemic: A Survey Of Its Impact On Mental Health
        date: 2020-06-18
       words: 2126
      flesch: 48
     summary: When enquired about the activities during the lockdown, only 11% were occupied with hobbies whereas WHO advises engaging in regular exercising, daily chores, and hobbies during the present COVID-19 pandemic for mental health well-being (WHO, 2020). Financial loss due to quarantine created severe socioeconomic distress (Pellecchia et al, 2015) and was established to be a contributing factor for symptoms of mental health disorders, anger and anxiety (Mihashi et al, 2009) .
    keywords: health; lockdown; study
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        item: #908 of 7819
          id: cord-258078-k7y8k1vx
      author: Jang, Sukbin
       title: Three cases of treatment with Nafamostat in elderly patients with COVID-19 pneumonia who need oxygen therapy
        date: 2020-05-26
       words: 1481
      flesch: 43
     summary: We experienced clinical and radiologic improvement in COVID-19 patients with pneumonia treated by nafamostat. These cases were treated with nafamostat in elderly patients with pneumonia who progressed while using antiviral drugs in a high-risk group with limited sample size and not through a randomized control study, and Highly pathogenic coronavirus N protein aggravates lung injury by MASP-2-mediated complement over-activation The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak-an update on the status SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Epidemiology, Pathogenesis, and Control of COVID-19 Thromboembolic risk and anticoagulant therapy in COVID-19 patients: Emerging evidence and call for action Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay
    keywords: covid-19; march; nafamostat
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        item: #909 of 7819
          id: cord-258084-nkr3lrov
      author: Juthani, Prerak
       title: Coronavirus Disease 2019 (COVID-19) Manifestation as Acute Myocardial Infarction in a Young, Healthy Male
        date: 2020-07-11
       words: 1759
      flesch: 42
     summary: World Health Organization, Pneumonia of Unknown Cause-China, World Health Organization e novel coronavirus 2019 (2019-NCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Short-term application of tocilizumab during myocardial infarction (STAT-MI) Cardiovascular disease and COVID-19 Laboratory abnormalities in patients with COVID-2019 infection Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults Risk factors for coronary heart disease in men 18 to 39 years of age Serum cholesterol in young men and subsequent cardiovascular disease Framingham risk score and prediction of coronary heart disease death in young men Impact of coronavirus disease 2019 (COVID-19) outbreak on ST-segmentelevation myocardial infarction care in Hong Kong, China e authors declare that they have no conflicts of interest. e incidence of acute cardiac injury in COVID-19 patients has been estimated to be approximately 8-12%
    keywords: covid-19; disease; patient; risk; sars
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        item: #910 of 7819
          id: cord-258092-a4e59c7z
      author: Pfeuffer, Steffen
       title: Autoimmunity complicating SARS-CoV-2 infection in selective IgA-deficiency
        date: 2020-08-12
       words: 826
      flesch: 43
     summary: Previous patients also developed GBS already within 7-10 days after the onset of COVID-19. Guillain-Barre syndrome: the first documented COVID-19-triggered autoimmune neurologic disease: more to come with myositis in the offing Rapid-onset diabetic ketoacidosis secondary to nivolumab therapy Selective IgA deficiency in autoimmune diseases Multireactive pattern of serum autoantibodies in asymptomatic individuals with immunoglobulin A deficiency Cranial neuropathies and COVID-19: neurotropism and autoimmunity Miller Fisher Syndrome and polyneuritis cranialis in COVID-19 Intubation, tracheostomy, and decannulation in patients with Guillain-Barre-syndrome-does dysphagia matter? Aventis.
    keywords: covid-19; day; sigad
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        item: #911 of 7819
          id: cord-258109-19zqd907
      author: Pasarikovski, Christopher R.
       title: The Impact of the Covid-19 Pandemic on Stroke Volume
        date: 2020-06-04
       words: 1080
      flesch: 43
     summary: With respect to the various means of patient presentation for code stroke activation (directly via emergency medical services [EMS], transfer from another hospital, emergency room walk-in, and inpatients), it appears that the decrease in code stroke volume is evenly distributed. Overall, there appears to be a decrease in code stroke volume since the global spread of Covid-19.
    keywords: covid-19; decrease; stroke
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        item: #912 of 7819
          id: cord-258118-j26v354r
      author: Karuppal, Raju
       title: It is time for a more cautious approach to surgical diathermy, especially in COVID-19 outbreak: A schematic review
        date: 2020-05-16
       words: 3538
      flesch: 37
     summary: The hazards of surgical smoke Surgical smoke and infection control Detecting hepatitis B virus in surgical smoke emitted during laparoscopic surgery. Apart from the numerous chemicals, surgical smoke had been shown to harbour intact bacterial and virus particles especially COVID-19 in the current time.
    keywords: chemical; covid-19; diathermy; electrocautery; hazards; health; laser; particles; smoke; tissue
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        item: #913 of 7819
          id: cord-258122-hkm9agqg
      author: Thorlund, Kristian
       title: A real-time dashboard of clinical trials for COVID-19
        date: 2020-04-24
       words: 460
      flesch: 30
     summary: key: cord-258122-hkm9agqg authors: Thorlund, Kristian; Dron, Louis; Park, Jay; Hsu, Grace; Forrest, Jamie I; Mills, Edward J title: A real-time dashboard of clinical trials for COVID-19 date: 2020-04-24 journal: Lancet Digit Health DOI: 10.1016/s2589-7500(20)30086-8 sha: doc_id: 258122 cord_uid: hkm9agqg nan In response to the global coronavirus disease 2019 (COVID-19) emergency, clinical trial research assessing the efficacy and safety of clinical candidate interventions to treat COVID-19 are emerging at an unprecedented rate. Findings from randomised clinical trials that have been published as of April 21, 2020, have investigated the efficacy of lopinavir-ritonavir compared with standard of care, 1 hydroxychloroquine compared with best supportive care, 2 favipiravir compared with arbidol, 3 and lopinavir-ritonavir compared with arbidol.
    keywords: covid-19; trials
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        item: #914 of 7819
          id: cord-258125-2kkqqgop
      author: Wagner, Peter
       title: Knowing How to Act Well in Time
        date: 2020-08-25
       words: 5068
      flesch: 51
     summary: Such knowledge will always be difficult to achieve but we can at least briefly spell out what, for want of better terms, can be called an ontological attitude and a methodological maxim. Pre-COVID-19 political sociology is at a loss to explain such government action.
    keywords: action; covid-19; crisis; knowledge; pandemic; public; society; time
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        item: #915 of 7819
          id: cord-258126-8ityzjjh
      author: Mamun, Mohammed A.
       title: COVID-19 suicides in Pakistan, dying off not COVID-19 fear but poverty? – The forthcoming economic challenges for a developing country
        date: 2020-05-11
       words: 1491
      flesch: 45
     summary: This study reports COVID-19 suicide cases in Pakistan for the first time. Besides, the decreasing of German Finance Minister is reported for economic recession suicide case rather than considering the general economic recession victims, that is totally unable to convey the evidence of lockdown-related economic recession suicides among the general people (Thakur & Jain, 2020) .
    keywords: cases; covid-19; recession; suicide
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        item: #916 of 7819
          id: cord-258128-qtmjgrml
      author: Mirjalili, Mahtabalsadat
       title: Coronavirus Disease 2019 (COVID-19) and Transplantation: Pharmacotherapeutic Management of Immunosuppression Regimen
        date: 2020-07-03
       words: 6459
      flesch: 30
     summary: Table 1 shows a summary of medications which are used or suggested for the management of COVID-19 patients, according to recent studies. Sometimes, medications other than antivirals are used for symptomatic therapy or supportive care in COVID-19 patients.
    keywords: coronavirus; covid-19; drug; effects; kidney; liver; management; patients; recipients; risk; studies; transplant; treatment; use
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        item: #917 of 7819
          id: cord-258133-zsweppku
      author: Fischer, M.
       title: COVID-19 paranoia in a patient suffering from schizophrenic psychosis – a case report
        date: 2020-04-17
       words: 1129
      flesch: 37
     summary: key: cord-258133-zsweppku authors: Fischer, M.; Coogan, A.N.; Faltraco, F.; Thome, J. title: COVID-19 paranoia in a patient suffering from schizophrenic psychosis – a case report date: 2020-04-17 journal: Psychiatry Res DOI: 10.1016/j.psychres.2020.113001 sha: doc_id: 258133 cord_uid: zsweppku nan The COVID-19 pandemic affects mental health, both in healthcare settings and broader society. However, the number of studies addressing such issues is very limited; one such study carried out during the 2009 swine influenza pandemic indicated that patients with schizophrenia and a high level of predicted fear tended to judge their own risk of infection as higher (Maguire et al., 2019a ).
    keywords: case; covid-19; patient; report
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        item: #918 of 7819
          id: cord-258135-9i024s08
      author: Konala, Venu Madhav
       title: Co-infection with Influenza A and COVID-19
        date: 2020-04-20
       words: 1218
      flesch: 46
     summary: COVID-19, modern pandemic: a systematic review from a front-line health care providers' perspective Precautions are needed for COVID-19 patients with coinfection of common respiratory pathogens The clinical characteristics of pneumonia patients co-infected with 2019 novel coronavirus and influenza virus in Wuhan Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label nonrandomized clinical trial All patients were treated with oseltamivir, antibiotics and supplemental oxygen, and three of the patients required steroids Many novel treatments for COVID-19 are under investigation, and although some of these options are already being used in clinical practice (as in our patient), none are currently approved for routine use. Many centres have started incorporating treatment with hydroxychloroquine and azithromycin based on a small study by Gautret et al., where the combination decreased the duration of viral shedding and increased elimination of the virus We currently do not know the impact on patients of co-infection with both influenza and COVID-19, or whether influenza alters clinical outcomes in patients already infected with COVID-19.
    keywords: covid-19; influenza; patients; wuhan
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        item: #919 of 7819
          id: cord-258137-np62exds
      author: Sharma, Surbhi
       title: Indians vs.COVID-19: The scenario of mental health
        date: 2020-09-07
       words: 1665
      flesch: 47
     summary: The Lancet, India under COVID-19 lockdown COVID-19 pandemic and lockdown: cause of sleep disruption, depression, somatic pain, and increased screen exposure of office workers and students of India Mental health of family, friends, and co-workers of COVID-19 patients in Japan Loss and grief amidst COVID-19: A path to adaptation and resilience Recognising and addressing the impact of COVID-19 on obsessive-compulsive disorder Resilience, COVID-19-related stress, anxiety and depression during the pandemic in a large population enriched for healthcare providers Mental health status of pregnant and breastfeeding women during the COVID-19 pandemic: A call for action Mitigate the effects of home confinement on children during the COVID-19 outbreak Mental health problems faced by healthcare workers due to the COVID-19 pandemic-A review Parenting in a time of COVID-19 COVID 19 pandemic: Mental health challenges of internal migrant workers of India Aggregated COVID-19 suicide incidences in India: Fear of COVID-19 infection is the prominent causative factor COVID 19 and its mental health consequences International Experiences of the Active Period of COVID-19 -Mental Health Care Effect of covid-19 pandemic on mental health among Albanian people residing in the country and abroad -Implications for mental care Ministry of Health and Family Welfare, CLINICAL MANAGEMENT PROTOCOL : Around 45% of adults reported an impact on mental health in the US
    keywords: covid-19; health; india; mental; pandemic
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        item: #920 of 7819
          id: cord-258145-usr7b6dk
      author: Abdulah, Deldar Morad
       title: Relation of Dietary Factors with Infection and Mortality Rates of COVID-19 Across the World
        date: 2020-07-04
       words: 3995
      flesch: 45
     summary: The study showed that the countries with higher infection rates between 1500 and above had a higher intake of fruits (P=0.002), fruit juices (P<0.001), calcium (P<0.001), potassium (P<0.001), and total milk (P<0.001). Therefore, we can make the further hypothesis that the aged population of the countries with high infection rates has been the main factor in the low immune system.
    keywords: countries; covid-19; fruits; immune; infection; intake; mortality; rate
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        item: #921 of 7819
          id: cord-258150-ezatw341
      author: Vilakati, Phesheya Ndumiso
       title: The neglected role of Faith-based Organizations in prevention and control of COVID-19 in Africa
        date: 2020-08-27
       words: 1295
      flesch: 36
     summary: In Africa, faith-based organizations (FBOs)-the values of which are based on religious and faith beliefs-which manage a vast number of health facilities in many low-income countries (for instance, approximately 40% of total health services and more than 1000 hospitals are managed by Catholic FBOs in Africa), 3-6 play an essential role in providing healthcare and prevention services, community education, and financing. Despite efforts of African Governments to promptly establish mitigating measures, rural areas, especially in sub-Saharan Africa, risk being neglected.
    keywords: africa; covid-19; health; pandemic
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        item: #922 of 7819
          id: cord-258170-kyztc1jp
      author: Shorfuzzaman, Mohammad
       title: Towards the sustainable development of smart cities through mass video surveillance: A response to the COVID-19 pandemic
        date: 2020-11-05
       words: 5374
      flesch: 44
     summary: Fan et al. (2020) presented a similar approach to social distancing monitoring with an autonomous surveillance quadruped robot that could promote social distancing in complex urban environments. Single shot multibox detector Low-cost implementation of bird's-eye view system for camera-on-vehicle Enabling and emerging technologies for social distancing: A comprehensive survey-rob Monitoring covid-19 social distancing with person detection and tracking via fine-tuned YOLOv3 and deepsort techniques Detection and Brain Mapping Visualization Inception U-Net architecture for semantic segmentation to identify nuclei in microscopy cell images Crowd analysis for congestion control early warning system on foot over bridge Social Event Classification via Boosted Multimodal Supervised Latent Dirichlet Allocation Data-driven dynamic clustering framework for mitigating the adverse economic impact of COVID-19 lockdown practices Yolo9000: better, faster, stronger Faster R-CNN: Towards real-time object detection with region proposal networks DeepSOCIAL: Social distancing monitoring and infection risk assessment in COVID-19 pandemic, medRxiv preprint The use of drones during mass events COVID-Robot: Monitoring social distancing constraints in crowded scenarios Towards sustainable smart cities: A review of trends, architectures, components, and open challenges in smart cities Very deep convolutional networks for large-scale image recognition Automatic Visual Concept Learning for Social Event Understanding Deep Relative Attributes The efficacy of social distance and ventilation effectiveness in preventing COVID-19 transmission Rethinking the inception architecture for computer vision Tensor2Tensor for neural machine translation Statement on the second meeting of the International Health Regulations (2005) Emergency Committee regarding the outbreak of novel coronavirus (2019-nCoV).
    keywords: covid-19; detection; distancing; monitoring; object; smart; system; video; view
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        item: #923 of 7819
          id: cord-258172-p54j4zzo
      author: Barker, Harlan
       title: Bioinformatic characterization of angiotensin-converting enzyme 2, the entry receptor for SARS-CoV-2
        date: 2020-10-28
       words: 8473
      flesch: 43
     summary: In lung, ACE2 expressing cells are generally uncommon with no cell type having a ratio of ACE2-expressing cells greater than 2.6%. [27] , whereas Sims and colleagues demonstrated ACE2 expression on the luminal surface of ciliated cells in freshly excised human nasal and tracheobronchial tissue
    keywords: ace2; analysis; angiotensin; binding; cells; cov-2; covid-19; data; expression; gene; human; lung; mrna; receptor; sars; tissues
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        item: #924 of 7819
          id: cord-258195-6172d95c
      author: Souadka, Amine
       title: Oncological Surgery During the COVID‐19 Pandemic: The Need for Deep and Lasting Measures
        date: 2020-06-23
       words: 670
      flesch: 33
     summary: A segregated-team model to maintain cancer care during the COVID-19 outbreak at an academic center in Singapore Preparing African anticancer centres in the COVID-19 outbreak The authors indicated no financial relationships. A practical approach to the management of cancer patients during the novel coronavirus disease 2019 (COVID-19) pandemic: An international collaborative group Cancer guidelines during the COVID-19 pandemic Cancer, COVID-19 and the precautionary principle: Prioritizing treatment during a global pandemic COVID-19:
    keywords: cancer; covid-19; patients
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        item: #925 of 7819
          id: cord-258221-pn8gh73b
      author: Rocha, José Lucas Martins
       title: Mesenchymal Stromal Cells in Viral Infections: Implications for COVID-19
        date: 2020-09-07
       words: 8981
      flesch: 36
     summary: The development of fibroblast colonies in monolayer cultures of Guinea-pig bone marrow and spleen cells The meaning, the sense and the significance: Translating the science of mesenchymal stem cells into medicine Plasticity of mesenchymal stem cells in immunomodulation: Pathological and therapeutic implications Immunoregulatory mechanisms of mesenchymal stem and stromal cells in inflammatory diseases Biological functions of mesenchymal stem cells and clinical implications Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC Proteomic analysis of human mesenchymal stromal cell secretomes: A systematic comparison of the angiogenic potential Hematopoietic support capacity of mesenchymal stem cells: Biology and clinical potential The use of human mesenchymal stem cells as therapeutic agents for the in vivo treatment of immune-related diseases: A systematic review The immunomodulatory functions of mesenchymal stromal/stem cells Stem Cell Rev and Rep mediated via paracrine activity Mechanisms involved in the therapeutic properties of mesenchymal stem cells Human umbilical cord mesenchymal stem cells hUC-MSCs exert immunosuppressive activities through a PGE2-dependent mechanism Human mesenchymal stem cells program macrophage plasticity by altering their metabolic status via a PGE 2 -dependent mechanism Mesenchymal stromal cells and their extracellular vesicles enhance the anti-inflammatory phenotype of regulatory macrophages by downregulating the production of interleukin (IL)-23 and IL-22 Apoptotic mesenchymal stromal cells induce prostaglandin E2 in monocytes: Implications for the monitoring of mesenchymal stromal cell activity Human placental mesenchymal stem cells (pMSCs) play a role as immune suppressive cells by shifting macrophage differentiation from inflammatory M1 to anti-inflammatory M2 macrophages Mesenchymal stromal cells modulate macrophages in clinically relevant lung injury models by extracellular vesicle mitochondrial transfer Mesenchymal-myeloid interaction in the regulation of immunity Properties and Function of Indoleamine 2, 3-Dioxygenase1 Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancer The interplay between Indoleamine 2,3-dioxygenase 1 (IDO1) and cyclooxygenase (COX)-2 in chronic inflammation and Cancer Overexpression of COX-2 but not indoleamine 2,3-dioxygenase-1 enhances the immunosuppressive ability of human umbilical cord-derived mesenchymal stem cells Kynurenic acid, an IDO metabolite, controls TSG-6-mediated immunosuppression of human mesenchymal stem cells Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-κB signaling in resident macrophages MSCs inhibit bone marrow-derived DC maturation and function through the release of TSG-6 Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cells Mesenchymal stem cells inhibit generation and function of both CD34 + −derived and monocyte-derived dendritic cells The anti-inflammatory protein TSG-6 regulates chemokine function by inhibiting chemokine/ glycosaminoglycan interactions Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation Interferon-γ does not break, but promotes the immunosuppressive capacity of adult human mesenchymal stem cells Cell contact, prostaglandin E2 and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+ CD25Highforkhead box P3+ regulatory T cells Mesenchymal stem cells generate a CD4+CD25+Foxp3 + regulatory T cell population during the differentiation process of Th1 and Th17 cells Inhibition of DNA methylation enhances HLA-G expression in human mesenchymal stem cells Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosis Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and Stem Cell Rev and Rep natural killer function and to induce CD4 + CD25 high FOXP3 + regulatory T cells Mesenchymal stem cells derived from human bone marrow and adipose tissue maintain their immunosuppressive properties after Chondrogenic differentiation: Role of HLA-G Characterization of HLA-G and related immunosuppressive effects in human umbilical cord stromaderived stem cells Mesenchymal stem cells upregulate Treg cells via sHLA-G in SLE patients Signaling to heme oxygenase-1 and its antiinflammatory therapeutic potential Human mesenchymal stem cells improve rat islet functionality under cytokine stress with combined upregulation of heme oxygenase-1 and ferritin Suppression of neutrophil-mediated tissue damage-A novel skill of mesenchymal stem cells Adenosinergic immunosuppression by human mesenchymal stromal cells requires co-operation with T cells Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a Proinflammatory phenotype Immunobiology of mesenchymal stem cells Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles Mesenchymal stromal cell secretome: Influencing therapeutic potential by cellular pre-conditioning Small non-coding RNA landscape of extracellular vesicles from human stem cells
    keywords: acute; cells; covid-19; expression; fig; human; infections; inflammatory; lung; mesenchymal; mesenchymal stem; mscs; patients; stem; stem cells; stromal; therapy; tissue; treatment; virus
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        item: #926 of 7819
          id: cord-258229-l716wjwn
      author: Fiorillo, Andrea
       title: Effects of the lockdown on the mental health of the general population during the COVID-19 pandemic in Italy: Results from the COMET collaborative network
        date: 2020-09-28
       words: 6718
      flesch: 42
     summary: During the lockdown participants reported an increased time spent on Internet, which was associated with a higher risk of developing mental health problems, thus not confirming our hypothesis of a protective effect played by Internet on mental health. The consequences of the COVID-19 pandemic on mental health and implications for clinical practice Psychological adjustment during the global outbreak of COVID-19: a resilience perspective The relevance of COVID-19 pandemic to psychiatry Update: use of quarantine to prevent transmission of severe acute respiratory syndrome-Taiwan The term physical distancing is recommended rather than social distancing during the COVID-19 pandemic for reducing feelings of rejection among people with mental health problems Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Redfeld RR Covid-19-navigating the uncharted Principles of mental health care during the COVID-19 pandemic The impact of the COVID-19 outbreak on the medico-legal and human rights of psychiatric patients Traumatic stress in the age of covid-19: a call to close critical gaps and adapt to new realities COVID-19 pandemic and mental health consequences: systematic review of the current evidence Unprecedented disruption of lives and work: health, distress and life satisfaction of working adults in China one month into the COVID-19 outbreak Do psychiatric patients experience more psychiatric symptoms during COVID-19 pandemic and lockdown?
    keywords: anxiety; covid-19; depressive; health; levels; lockdown; pandemic; population; scale; stress; study; symptoms
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        item: #927 of 7819
          id: cord-258230-s4ty52kb
      author: Grover, Abhinav
       title: A systematic review and meta-analysis to evaluate the clinical outcomes in COVID-19 patients on angiotensin-converting enzyme inhibitors or angiotensin receptor blockers
        date: 2020-06-15
       words: 2547
      flesch: 38
     summary: In light of these findings and a paucity of clinical outcome studies, many professional cardiovascular and hypertension societies including the European Society of Cardiology, Italian Society of Pharmacology, International Society of Hypertension (ISH), European Society of Hypertension, Joint American Heart Association/American College of Cardiology/ American Heart Failure Association, and others recommended the continued use of ACEIs/ARBs in COVID-19 patients. [8] [9] [10] [11] [12] However, since the conception of these recommendations, several clinical studies have been conducted which evaluated the association of ACEIs and ARBs with clinical severity and mortality outcomes in COVID-19 patients.
    keywords: arb; covid-19; outcomes; patients; studies
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        item: #928 of 7819
          id: cord-258235-khdyxiwe
      author: Chakraborty, Tanujit
       title: Real-time forecasts and risk assessment of novel coronavirus (COVID-19) cases: A data-driven analysis
        date: 2020-04-30
       words: 5631
      flesch: 51
     summary: Daubechies wavelets can produce identical events across the observed time series in so many fashions that most other time series prediction models cannot recognize [3] . ARIMA model is denoted by ARIMA(p, d, q).
    keywords: arima; cases; countries; covid-19; data; forecasting; forecasts; model; series; time
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        item: #929 of 7819
          id: cord-258242-xblxjlb5
      author: Liu, Tengwen
       title: Systems Pharmacology and Verification of ShenFuHuang Formula in Zebrafish Model Reveal Multi-Scale Treatment Strategy for Septic Syndrome in COVID-19
        date: 2020-09-15
       words: 5218
      flesch: 38
     summary: Thus, SFH treatment may help to improve the coagulopathy of COVID-19 patients. This study provided additional evidence of SFH formula for treating COVID-19 patients with septic syndrome using multiple-scale estimation.
    keywords: coagulation; compounds; covid-19; formula; model; patients; sepsis; sfh; targets; treatment; zebrafish
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        item: #930 of 7819
          id: cord-258278-25rhf91v
      author: Mowla, Ashkan
       title: Unusual Pattern of Arterial Macrothrombosis Causing Stroke in a Young Adult Recovered from COVID-19
        date: 2020-09-25
       words: 2057
      flesch: 39
     summary: (1,2,3,9 ,10) Our patient characteristics and imaging findings were notable for the following aspects: Young Age: The majority of COVID-19 patients with large vessel stroke reported thus far were older with underlying co-morbidities and conventional cardiovascular risk factors. This is in line with the outcome of other young COVID-19 patients with large vessel stroke reported thus far displaying poor prognosis.
    keywords: covid-19; infection; patient; stroke; symptoms; vessel
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        item: #931 of 7819
          id: cord-258281-gxwk8jq9
      author: Wenling, Yao
       title: Pregnancy and COVID-19: management and challenges
        date: 2020-08-31
       words: 5024
      flesch: 39
     summary: Considering that SARS-CoV-2, SARS-CoV, and MERS-CoV are all β-coronaviruses, and their genomes, pathogenesis and clinical symptoms have certain similarities, this article draws lessons from previous studies on SARS-CoV and MERS-CoV infecting pregnant women to predict the impact of SARS-CoV-2 on pregnant women and fetuses and make some suggestions. In the same hospital, another newborn had confirmed COVID-19 infection 17 days after birth and a history of close contact with two confirmed cases 55 , the infant's mother and the maternity matron.
    keywords: coronavirus; cov-2; covid-19; infection; mers; patients; pregnancy; sars; syndrome; women
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        item: #932 of 7819
          id: cord-258304-86gqxajw
      author: Bahl, Prateek
       title: Droplets and Aerosols generated by singing and the risk of COVID-19 for choirs
        date: 2020-09-18
       words: 1554
      flesch: 49
     summary: To capture the video, the head of the subject was adjusted in front of black backdrop/background and the light was positioned in a forward scatter arrangement to maximize the scattering from expelled droplets ( Figure 1 ). While social distancing is effective in normal social interactions, singing can produce a substantially larger number of respiratory droplets and aerosols than speaking, as it is louder and sustained for longer durations
    keywords: covid-19; droplets; singing; velocities
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        item: #933 of 7819
          id: cord-258315-yt1ytasw
      author: Kato, Hideaki
       title: Clinical course of 2019 novel coronavirus disease (COVID-19) in individuals present during the outbreak on the Diamond Princess cruise ship
        date: 2020-05-13
       words: 1778
      flesch: 50
     summary: Because individuals with severe conditions during an outbreak are possibly transferred to nearby local hospitals, managing patients during an outbreak is a big challenge to local medical systems. The conditions and clinical courses of patients with pneumonia were compared with those of patients without pneumonia.
    keywords: covid-19; cruise; patients; pneumonia; ship
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        item: #934 of 7819
          id: cord-258337-3wua0iij
      author: Gale, Robert Peter
       title: A Haematologist's Guide to Coronavirus Disease 2019: Encyclopaedia or Doorstop?
        date: 2020-10-08
       words: 991
      flesch: 62
     summary: For those who think medical reversals are uncommon I recommend Ending Medical Reversal: Improving Outcomes, Saving Lives by Prasad and Cifu [5] . Coronavirus disease 2019 (CO-VID-19): a haematologist's perspective Hematological features of persons with COVID-19 A predictive score for progression of COVID-19 in hospitalized persons: a cohort study Perspective: SARS-CoV-2, COVID-19 and haematologists Ending medical reversal: improving outcomes, saving lives Can a disease be conquered by extensive publications, reading guidelines and interminable meetings?
    keywords: covid-19; study; subjects
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        item: #935 of 7819
          id: cord-258344-55n3wwle
      author: Khalafallah, Adham M.
       title: In Reply to the Letter to the Editor Regarding “Impact of COVID-19 on an Academic Neurosurgery Department: The Johns Hopkins Experience”
        date: 2020-08-08
       words: 389
      flesch: 0
     summary: We agree that it is crucial for neurosurgeons to begin clearing patient 12 backlogs of canceled elective cases to avoid disease progression and worse prognosis among Impact of COVID-19 on an Academic Neurosurgery Department: The Johns Hopkins Experience The end of social confinement and COVID-19 re-emergence risk Expected impact of lockdown in Île-de-France and possible exit strategies An Exit Strategy for Resuming Nonemergency Neurosurgery after Severe Acute Respiratory Syndrome Coronavirus 2: A United Kingdom Perspective Cancer Surgery Scheduling During and After the COVID-19 First Wave: The MD Anderson Cancer Center Experience The Return Back to Typical Practice from the Battle Plan of the COVID-19 Pandemic: A Comparative Study Tracking the Volume of Neurosurgical Care during the COVID-19 Pandemic Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans Letter: Safety Considerations for Neurosurgical Procedures During the COVID-19 Pandemic Letter: A Guide to the Prioritization of Neurosurgical Cases After the COVID-19 Pandemic SARS-CoV-2 Impact on Elective Orthopaedic Surgery: Implications for Post-Pandemic Recovery key: cord-258344-55n3wwle authors: Khalafallah, Adham M.; Jimenez, Adrian E.; Mukherjee, Debraj title: In Reply to the Letter to the Editor Regarding “Impact of COVID-19 on an Academic Neurosurgery Department: The Johns Hopkins Experience” date: 2020-08-08 journal: World Neurosurg DOI: 10.1016/j.wneu.2020.08.033 sha: doc_id: 258344 cord_uid: 55n3wwle nan The authors thank Dr. Venkataram and colleagues for their thoughtful and thorough 1 analysis of our recent study Impact of COVID-19 on an Academic Neurosurgery Department: 2
    keywords: covid-19; pandemic
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        item: #936 of 7819
          id: cord-258381-h0ddqs53
      author: Chhabra, Saurabh
       title: Diagnostic considerations for COVID-19 in recipients of allogeneic hematopoietic cell transplantation
        date: 2020-06-23
       words: 1020
      flesch: 26
     summary: Similarly published studies in COVID-19 and other viral illnesses have shown that convalescent plasma therapy is more effective earlier in the disease course with recovery either less likely or taking much longer in COVID-19 patients who have acute respiratory distress syndrome 7-9 . and special considerations in the vulnerable population of allogeneic HCT recipients 6 . Time is of the essence in the immunocompromised host and if ARDS has set in by the time the diagnosis of pulmonary COVID-19 is made, an effective treatment window may have been lost.
    keywords: bronchoscopy; covid-19; patients
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        item: #937 of 7819
          id: cord-258395-m9ws5rmv
      author: Johnson, Joshua K
       title: Frequency of Physical Therapist Intervention Is Associated With Mobility Status and Disposition at Hospital Discharge for Patients With COVID-19
        date: 2020-09-28
       words: 3954
      flesch: 33
     summary: Patients with COVID-19 demonstrated improved mobility at hospital discharge and higher probability of discharging home with increased frequency and longer mean duration of physical therapy visits. In this examination of data for patients treated in one of eleven hospitals in a single health system for COVID-19, we identified that higher frequency of physical therapy visits and longer individual visits are both significantly associated with better mobility status at hospital discharge and with increased 10 probability of discharging to home.
    keywords: discharge; home; hospital; mobility; patients; therapy; visit
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        item: #938 of 7819
          id: cord-258399-difauneh
      author: Rahmani, Amir Masoud
       title: Coronavirus disease (COVID-19) prevention and treatment methods and effective parameters: A systematic literature review
        date: 2020-10-22
       words: 10491
      flesch: 39
     summary: An Updated Meta-Analysis Early nutritional supplementation in non-critically ill patients hospitalized for the 2019 novel coronavirus disease (COVID-19): Rationale and feasibility of a shared pragmatic protocol A Case Report of a COVID-19-Associated Hyperactive Intensive Care Unit Delirium With Proposed Pathophysiology and Treatment Four point-of-care lateral flow immunoassays for diagnosis of COVID-19 and for assessing dynamics of antibody responses to SARS-CoV-2 SARS-CoV-2-specific antibody detection in healthcare workers in Germany with direct contact to COVID-19 patients Understanding antibody testing for covid-19 Analyzing barriers for implementation of public health and social measures to prevent the transmission of COVID-19 disease using DEMATEL method The COVID-19 pandemic calls for spatial distancing and social closeness: not for social distancing Does culture matter social distancing under the COVID-19 pandemic Influence of wind and relative humidity on the social distancing effectiveness to prevent COVID-19 airborne transmission: A numerical study Population flow drives spatiotemporal distribution of COVID-19 in China Adolescents' motivations to engage in social distancing during the COVID-19 pandemic: Associations with mental and social health Predicting the Growth and Trend of COVID-19 Pandemic using Machine Learning and Cloud Computing Collective action and social distancing in COVID-19 responses. The positive impact of the review in various angles on people's level of awareness for self-caring and facing the disease An overall review has to investigate many proposed approaches to confront COVID-19 disease and the virus outbreak, whereas the previous SLR-based case studies focused on the particular fields of facing methods such as different observations of PCR's tests.
    keywords: case; covid-19; detection; disease; et al; health; impact; methods; outbreak; parameters; patients; people; studies; study; symptoms; treatment; virus; ✗ ✗
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        item: #939 of 7819
          id: cord-258402-9s57thvn
      author: Dabas, Vineet
       title: Management of Orthopaedic Accidental Emergencies Amidst COVID-19 Pandemic: Our Experience in Preparing to Live with Corona
        date: 2020-09-10
       words: 3714
      flesch: 49
     summary: All the wastes pertaining to COVID-19 patients (suspects/positives) were discarded in dedicated yellow bags, be it plastic/ cotton/latex or human waste. Suspected COVID-19 patients who were stable but had a clear-cut need for surgery, like femoral neck fractures, closed displaced intra-articular fractures, irreducible long bone fractures, etc. were given primary treatment in the form of fluids, temporary stabilization with splints, plasters and dressings.
    keywords: care; covid-19; health; management; orthopaedic; patients; period; surgery
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        item: #940 of 7819
          id: cord-258410-ggrrbq5u
      author: Ganguly, Shuvadeep
       title: Teleconsultations and Shared Care in Pediatric Oncology During COVID-19
        date: 2020-09-22
       words: 1252
      flesch: 33
     summary: Our experience with telemedicine and developing this shared care model suggests that it is a feasible approach, and that even after COVID-19 pandemic wanes away, this will perhaps remain as a healthy legacy of the pandemic. COVID-19 in children with cancer in New York city Impact of the coronavirus disease 2019 (COVID-19) pandemic on pediatric oncology care in the Middle East The COVID-19 pandemic: a rapid global response for children with cancer from Managing pediatric cancer patients in COVID19 pandemic Metronomic therapy in pediatric oncology: a snapshot. Staying near the hospital during the whole treatment course and travelling regularly from their residential states for physical consultations during maintenance/followup period adds a significant indirect financial burden to an already prohibitive cost of cancer care for most of the families.
    keywords: cancer; care; covid-19; pandemic
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        item: #941 of 7819
          id: cord-258416-1jrbu8ox
      author: Drenovska, Kossara
       title: Covid‐19 pandemic and the skin
        date: 2020-09-21
       words: 1986
      flesch: 26
     summary: Coronavirus Illinois Chilblain-like lesions during COVID-19 epidemic: a preliminary study on 63 patients Chilblains are a common cutaneous finding during the COVID-19 pandemic: a retrospective nationwide study from France Characterization of acute acro-ischemic lesions in nonhospitalized patients: a case series of 132 patients during the COVID-19 outbreak Coagulopathy and antiphospholipid antibodies in patients with Covid-19 Viral infections and antiphospholipid antibodies COVID-19 can present with a rash and be mistaken for dengue Reply to COVID-19 can present with a rash and be mistaken for dengue: Petechial rash in a patient with COVID-19 infection A dermatologic manifestation of COVID-19: transient livedo reticularis Histopathological study of 3 cases of new coronavirus pneumonia (COVID-19) with multi-site puncture Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases SARS-COV-2 infection is likely to be androgen mediated A preliminary observation: Male pattern hair loss among hospitalized COVID-19 patients in Spain -A potential clue to the role of androgens in COVID-19 severity What does androgenetic alopecia have to do with COVID-19? Case Rep Pediatr Clinical characteristics of children with viral single-and co-infections and a petechial rash Cutaneous manifestations in COVID-19: a first perspective Comment on 'Cutaneous manifestations in COVID-19: a first perspective' by Recalcati S A case of COVID-19 pneumonia in a young male with full body rash as a presenting symptom Rash as a clinical manifestation of COVID19.
    keywords: coronavirus; covid-19; disease; pandemic; patients; skin
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        item: #942 of 7819
          id: cord-258484-jwgtjisx
      author: Mehrabi, Sara
       title: Pitfalls of Computed Tomography in the Coronavirus 2019 (COVID-19) Era: A New Perspective on Ground-Glass Opacities
        date: 2020-05-16
       words: 2993
      flesch: 33
     summary: Chest CT plays a pivotal role in the detection and early management of COVID-19 pneumonia; despite its sensitivity, it lacks specificity because of the wide spectrum of pathologies that can show GGO. The aim of our study is to show chest CT findings that could mimic COVID-19 pneumonia; in the COVID-19 era, we should not forget other lung diseases that could be misinterpreted in our experience.
    keywords: covid-19; ggo; lung; patients; pcr; pneumonia
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        item: #943 of 7819
          id: cord-258498-0mvxwo3w
      author: Shah, Saleha
       title: COVID-19 and paediatric dentistry- traversing the challenges. A narrative review
        date: 2020-08-21
       words: 13563
      flesch: 44
     summary: DHCP recovered from COVID-19 (protective immunity) care for COVID-19 patient. DHCP recovered from COVID-19 (protective immunity) care for COVID-19 patient.
    keywords: advice; air; care; caries; children; control; covid-19; day; dhcp; dose; emergency; face; fluoride; infection; management; nsaids; pain; patient; risk; symptoms; tooth; transmission; use; water; years
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        item: #944 of 7819
          id: cord-258500-zuuwqw9t
      author: Desroches, Melissa L.
       title: Impact of COVID-19: Nursing challenges to meeting the care needs of people with developmental disabilities
        date: 2020-11-04
       words: 4339
      flesch: 40
     summary: The first federal support for DD care came in 1972 with the authorization of Intermediate Care Facilities for Intellectual Disabilities (ICF/IID) 13 . All 50 states currently participate in the HCBS waiver program 13 , and the majority of public funding for DD care is now provided through HCBS waivers 17 .
    keywords: care; covid-19; health; needs; nurses; pandemic; people; staff
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        item: #945 of 7819
          id: cord-258505-4ec9n4d0
      author: Titov, Nickolai
       title: Rapid report: Early demand, profiles and concerns of mental health users during the coronavirus (COVID-19) pandemic
        date: 2020-06-01
       words: 2338
      flesch: 44
     summary: Analyses Descriptive analyses of demographic and symptom characteristics were conducted and group differences between the comparison sample and COVID-19 sample were made using ANOVA and chi-square statistics to a significance level of .05. There are several possible reasons for the increased demand for MindSpot services, including increased distress levels in the population, the temporary closure of existing face-to-face services, and increased promotion of MindSpot by other services that were unable to meet patients needs.
    keywords: covid-19; health; mindspot; pandemic; period
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        item: #946 of 7819
          id: cord-258535-2m369sm5
      author: Radbel, Jared
       title: Use of Tocilizumab for COVID-19-Induced Cytokine Release Syndrome: A Cautionary Case Report
        date: 2020-04-25
       words: 1691
      flesch: 43
     summary: However, several clinical trials are actively recruiting subjects to determine the safety and efficacy of tocilizumab in the treatment of severe COVID-19 pneumonia in adult patients. Bethesda, MD: National Institutes of Health A study to evaluate the safety and efficacy of tocilizumab in patients with severe COVID-19 pneumonia (COVACTA).
    keywords: covid-19; crs; il-6; patients; tocilizumab
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        item: #947 of 7819
          id: cord-258548-1u7v1nlr
      author: Mansueto, Gelsomina
       title: Can COVID 2019 disease induces a specific cardiovascular damage or it exacerbates pre-existing cardiovascular diseases?
        date: 2020-06-26
       words: 5929
      flesch: 25
     summary: Heart damage patients had higher mortality than those without heart damage. The 3 main symptoms of COVID-19 disease are fever, cough, and shortness of breath.
    keywords: acute; cells; cov-2; covid-19; damage; disease; heart; infection; inflammatory; patients; risk; sars; study; virus
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        item: #948 of 7819
          id: cord-258562-raubqnko
      author: Murlimanju, Bukkambudhi V.
       title: Letter to Editor Regarding: “Decrease in Neurosurgical Program Volume During COVID-19: Residency Programs Must Adapt”
        date: 2020-09-23
       words: 713
      flesch: 37
     summary: It is important to note that most neurosurgical residency programs are provided in academic hospitals, which are mainly based in urban centers. It will be very useful if the interns could be given more number of days in neurosurgical training because they might have been exposed to a very small number of neurosurgical patients owing to the COVID-19 pandemic.
    keywords: covid-19; decrease; programs
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        item: #949 of 7819
          id: cord-258576-ywbyflas
      author: Bösmüller, Hans
       title: The evolution of pulmonary pathology in fatal COVID-19 disease: an autopsy study with clinical correlation
        date: 2020-06-30
       words: 3638
      flesch: 38
     summary: The hypercoagulability may also contribute to the observed mortality by triggering cardiovascular events before the development of severe pulmonary disease [11, 20, 21] . In addition to severe pulmonary disease, disseminated coagulation and thrombus formation triggered by multifactorial endothelial damage are frequent events in fatal SARS-CoV-2 infection.
    keywords: alveolar; autopsy; covid-19; damage; disease; failure; il-6; patients; sars
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        item: #950 of 7819
          id: cord-258577-uo55dj39
      author: Crockett, Jennifer L.
       title: Rapid Conversion from Clinic to Telehealth Behavioral Services During the COVID-19 Pandemic
        date: 2020-10-15
       words: 5881
      flesch: 41
     summary: Moreover, our department had already begun the process of approving and training clinicians for telehealth services, and about a third of those appointments (n = 222) were telehealth appointments. When providing telehealth services, many considerations, rules, and regulations should be addressed.
    keywords: appointments; behavior; clients; consent; covid-19; data; department; insurance; providers; regulations; services; telehealth
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        item: #951 of 7819
          id: cord-258579-68suyath
      author: Villar, Sergio Ciria
       title: Sintomatología psicótica en relación con cuarentena por COVID-19
        date: 2020-11-07
       words: 1854
      flesch: 34
     summary: No existe por el momento suficiente investigación sobre la Conviene tener en cuenta tanto la posibilidad de aparición de alteraciones psiquiátricas en personas que no tienen Durante las últimas semanas, la paciente había estado cada vez más irritable, puesto que tenía previsto viajar a Francia con su familia y la situación de emergencia sanitaria se lo impidió.
    keywords: como; con; covid-19; fue; las; los; mental; paciente; por; que
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        item: #952 of 7819
          id: cord-258581-46p0k9lc
      author: Bodak, Nathalie
       title: COVID‐19 Lockdown induced acral dermatosis in children
        date: 2020-06-28
       words: 557
      flesch: 45
     summary: key: cord-258581-46p0k9lc authors: Bodak, Nathalie; Chiaverini, Christine; Barbarot, Sebastien title: COVID‐19 Lockdown induced acral dermatosis in children date: 2020-06-28 journal: J Eur Acad Dermatol Venereol DOI: 10.1111/jdv.16797 sha: doc_id: 258581 cord_uid: 46p0k9lc Recently, several case series of cutaneous acral manifestations in patients with suspected or confirmed coronavirus disease 2019 (COVID‐19) have been reported. Although a larger case series would strengthen our hypothesis, we suggest that the change of daily habits in young children during the lockdown period may have increased the frequency of acral frictional dermatoses that are not directly due to the virus but rather to prolonged sessions spent playing on the floor.
    keywords: children; covid-19
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        item: #953 of 7819
          id: cord-258583-5qdthy0j
      author: Yan, He
       title: Multiple organ injury on admission predicts in‐hospital mortality in patients with COVID‐19
        date: 2020-09-30
       words: 2584
      flesch: 39
     summary: World Health Organization Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China Kidney disease is associated with inhospital death of patients with COVID-19 Clinical features and short-term outcomes of 102 patients with coronavirus disease Clinical characteristics of 82 cases of death from COVID-19 Acute myocardial injury at hospital admission is associated with all-cause mortality in COVID-19 Comorbid chronic diseases and acute organ injuries are strongly correlated with disease severity and mortality among COVID-19 patients: a systemic review and metaanalysis Clinical characteristics of 36 nonsurvivors with COVID-19 in Wuhan, China. However, it remains uncertain whether liver injury affects the mortality of COVID-19 patients, 4, 5 although it occurred more commonly in patients who had severe COVID-19 than mild ones.
    keywords: clinical; covid-19; disease; injury; mortality; patients
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        item: #954 of 7819
          id: cord-258602-dnzqiq8k
      author: Cortegiani, A.
       title: Rationale and Evidence on the use of Tocilizumab in COVID-19: A Systematic Review
        date: 2020-07-20
       words: 1856
      flesch: 41
     summary: These include several pre-clinical studies describing a beneficial effect in cellular and murine models of sepsis and influenza 15- In a cell model of sepsis (Human monocyte cell line THP-1), tocilizumab reduced the expression of TNF and IL-10, down-regulated inflammasome activation (reduced levels of NLRP3 and CASP1) and inhibited monocyte phagocytic activity. Three papers described preclinical studies and 28 papers described clinical studies.
    keywords: covid-19; patients; studies; tocilizumab; treatment
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        item: #955 of 7819
          id: cord-258624-041cf99j
      author: Ahmad, Sajjad
       title: Design of a Novel Multi Epitope-Based Vaccine for Pandemic Coronavirus Disease (COVID-19) by Vaccinomics and Probable Prevention Strategy against Avenging Zoonotics
        date: 2020-05-23
       words: 8231
      flesch: 43
     summary: The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health &#x2014; The latest 2019 novel coronavirus outbreak in Wuhan, China Novel Coronavirus (2019-nCoV) Situation Summary | CDC A novel coronavirus outbreak of global health concern ScienceDaily: Your source for the latest research news Database resources of the national center for biotechnology information Exoproteome and secretome derived broad spectrum novel drug and vaccine candidates in Vibrio cholerae targeted by Piper betel derived compounds Combating tigecycline resistant Acinetobacter baumannii: A leap forward towards multi-epitope based vaccine discovery Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes The HMMTOP transmembrane topology prediction server SPAAN: a software program for prediction of adhesins and adhesin-like proteins using neural networks Adhesins as targets for vaccine development The immune epitope database (IEDB): 2018 update Improved method for predicting linear B-cell epitopes BepiPred-2.0: improving sequencebased B-cell epitope prediction using conformational epitopes MHCPred: a server for quantitative prediction of peptide--MHC binding Identification of putative vaccine candidates against Helicobacter pylori exploiting exoproteome and secretome: a reverse vaccinology based approach VirulentPred: a SVM based prediction method for virulent proteins in bacterial pathogens Vaxign: the first web-based vaccine design program for reverse vaccinology and applications for vaccine development AllerTOP-a server for in silico prediction of allergens Multi-epitope vaccines: a promising strategy against tumors and viral infections Peptide vaccine: progress and challenges Development of a multi-epitope peptide vaccine inducing robust T cell responses against brucellosis using immunoinformatics based approaches Exploring dengue genome to construct a multi-epitope based subunit vaccine by utilizing immunoinformatics approach to battle against dengue infection SCRATCH: a protein structure and structural feature prediction server I-TASSER server for protein 3D structure prediction homology modelling of protein structures and complexes others, Galaxy: a platform for interactive large-scale genome analysis GalaxyRefine: protein structure refinement driven by side-chain repacking Disulphide bonds and protein stability Disulfide by Design 2.0: a web-based tool for disulfide engineering in proteins Codon usage: nature's roadmap to expression and folding of proteins JCat: a novel tool to adapt codon usage of a target gene to its potential expression host Novel immunoinformatics approaches to design multi-epitope subunit vaccine for malaria by investigating anopheles salivary protein In-silico design of a multi-epitope vaccine candidate against onchocerciasis and related filarial diseases Computational immunology meets bioinformatics: the use of prediction tools for molecular binding in the simulation of the immune system PATCHDOCK and SymmDock: servers for rigid and symmetric docking FireDock: fast interaction refinement in molecular docking RRDistMaps: a UCSF Chimera tool for viewing and comparing protein distance maps Discovery studio visualizer VMD: visual molecular dynamics A one-pot multicomponent facile synthesis of dihydropyrimidin-2(1: H)-thione derivatives using triphenylgermane as a catalyst and its binding pattern validation Antechamber: an accessory software package for molecular mechanical calculations The FF14SB force field Langevin stabilization of molecular dynamics A fast SHAKE algorithm to solve distance constraint equations for small molecules in molecular dynamics simulations On the Berendsen thermostat CPPTRAJ: software for processing and analysis of molecular dynamics trajectory data UCSF Chimera-Superimposing and Morphing MMPBSA.py: This was significant to evaluate as homology between virus protein (s) to be used in vaccine designing and the host is likely to cause strong autoimmune reactions in the host [58] .
    keywords: binding; candidates; cell; construct; coronavirus; covid-19; energy; epitopes; glycoprotein; host; human; mepvc; molecular; protein; receptors; score; structure; system; tlr3; tlr4; vaccine
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        item: #956 of 7819
          id: cord-258662-6y45gb0t
      author: Butt, Nausharwan
       title: Cardiovascular complications in COVID-19
        date: 2020-07-19
       words: 114
      flesch: 16
     summary: key: cord-258662-6y45gb0t authors: Butt, Nausharwan; Arshid, Awais; Ahmad, Sarah Aftab; Khalid, Nauman; Kayani, Waleed Tallat title: Cardiovascular complications in COVID-19 date: 2020-07-19 journal: Am J Emerg Med DOI: 10.1016/j.ajem.2020.07.032 sha: doc_id: 258662 cord_uid: 6y45gb0t nan In summary, COVID-19 is associated with significant cardiovascular complications which may also include pericarditis, pericardial effusion and Takotsubo (stress) cardiomyopathy. Cardiovascular complications in COVID-19 SARS-CoV-2 detection in the pericardial fluid of a patient with cardiac tamponade COVID-19 (SARS-Cov-2) and the heart -An ominous association All authors have no sources of funding to disclose The authors have no conflict of interest to declare.
    keywords: covid-19
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        item: #957 of 7819
          id: cord-258669-ubw6mdzi
      author: Colebunders, Robert
       title: A call for strengthened evidence on targeted, non-pharmaceutical interventions against COVID-19 for the protection of vulnerable individuals in sub-Saharan Africa
        date: 2020-08-27
       words: 2517
      flesch: 35
     summary: We suggest investigating the feasibility, acceptability, and efficacy of distributing COVID-19 prevention kits to households with persons at increased risk for severe COVID-19 disease. One strategy could be to distribute COVID-19 prevention kits to households with persons at increased risk for severe COVID-19 disease.
    keywords: africa; covid-19; disease; risk
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        item: #958 of 7819
          id: cord-258670-dphg8ukj
      author: Karaahmet, Fatih
       title: Endothelial progenitor cells and mesenchymal stem cells to overcome vascular deterioration and cytokine storm in critical patients with COVID-19
        date: 2020-06-10
       words: 600
      flesch: 20
     summary: key: cord-258670-dphg8ukj authors: Karaahmet, Fatih; Altan Kocaman, Sinan title: Endothelial progenitor cells and mesenchymal stem cells to overcome vascular deterioration and cytokine storm in critical patients with COVID-19 date: 2020-06-10 journal: Med Hypotheses DOI: 10.1016/j.mehy.2020.109973 sha: doc_id: 258670 cord_uid: dphg8ukj nan Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 or COVID-2019) is an emerging global health threatening viral infection pathogen, originating from Wuhan, Autoimmunity and infectious agents seems potential immunologic triggers in COVİD-19. In light of this information, the sufficient repair of the endothelial lining of blood vessels with Endothelial progenitor cells (EPCs) treatment may have a crucial role to overcome the vascular collapse driving forces in COVID-19 patients, as well as to modulate human immune system.
    keywords: covid-19; endothelial
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        item: #959 of 7819
          id: cord-258675-nh1zu0yu
      author: Quesada, J. A.
       title: Período de incubación de la COVID-19: revisión sistemática y metaanálisis
        date: 2020-10-01
       words: 2673
      flesch: 50
     summary: Según los datos publicados sobre el período de incubación de la COVID-19, el tiempo medio entre la exposición y la aparición de los síntomas clínicos depende del modelo estadístico utilizado y el percentil 95, de la edad media de los pacientes. Según los datos publicados sobre el período de incubación de la COVID-19, el tiempo medio entre la exposición y la aparición de los síntomas clínicos depende del modelo estadístico utilizado y el percentil 95, de la edad media de los pacientes.
    keywords: del; días; edad; estudios; incubación; los; percentil; período; que
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        item: #960 of 7819
          id: cord-258676-6kgxpcwc
      author: Haleem, Abid
       title: Areas of academic research with the impact of COVID-19
        date: 2020-04-15
       words: 1351
      flesch: 50
     summary: SARS-CoV-2 is the name of the virus responsible for causing COVID-19 disease, which is highly infectious and lethal. key: cord-258676-6kgxpcwc authors: Haleem, Abid; Javaid, Mohd; Vaishya, Raju; Deshmukh, S.G. title: Areas of academic research with the impact of COVID-19 date: 2020-04-15 journal: Am J Emerg Med DOI: 10.1016/j.ajem.2020.04.022 sha: doc_id: 258676 cord_uid: 6kgxpcwc Coronavirus (COVID-19) endemic is growing exponentially in the whole world.
    keywords: covid-19; disease; pandemic; research
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        item: #961 of 7819
          id: cord-258698-ggzvhamk
      author: Hong, Daqing
       title: Kidney manifestations of mild, moderate and severe coronavirus disease 2019: a retrospective cohort study
        date: 2020-05-09
       words: 3088
      flesch: 52
     summary: This retrospective study included two major consecutive cohorts of COVID-19 patients in Sichuan Province. This is probably due to viremia, as positive SARS-CoV-2 detected by real-time polymerase chain reaction in plasma samples was found in 15% of COVID-19 patients [1] . Acute kidney injury (AKI) can occur in COVID-19 but its clinical epidemiological features remain unclear.
    keywords: cohort; covid-19; dipstick; hematuria; patients; proteinuria; study
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        item: #962 of 7819
          id: cord-258701-jyzxu9nk
      author: Kaushal, Darwin
       title: Endoscopy in Otorhinolaryngology During Corona Outbreak: A Proposal for Safe Practice
        date: 2020-08-13
       words: 2466
      flesch: 51
     summary: Screen the temperature prior to procedure Procedure area Three rooms required • Entry through first room for Donning. Minimise the number of HCWs in the procedure room when performing a procedure on COVID-19 positive patients.
    keywords: coronavirus; covid-19; endoscopies; endoscopy; health; procedure; room
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        item: #963 of 7819
          id: cord-258708-da6x5rxa
      author: Hafiane, Anouar
       title: SARS-CoV-2 and the cardiovascular system
        date: 2020-07-16
       words: 4043
      flesch: 34
     summary: Accumulating data points to an increased cardiovascular disease morbidity, and mortality in COVID-19 patients. COVID-19 patients presented with mild flu-like symptoms, and a few patients rapidly develop acute respiratory distress syndrome, respiratory failure, multiple organ failure, and even deaths ( Table 1 ).
    keywords: ace2; acute; angiotensin; cardiac; coronavirus; cov-2; covid-19; infection; patients; sars
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        item: #964 of 7819
          id: cord-258722-1o6zhnnj
      author: Gbinigie, Kome
       title: Should azithromycin be used to treat COVID-19? A rapid review
        date: 2020-05-13
       words: 3323
      flesch: 47
     summary: In vivo studies were included assessing the effectiveness and/or safety of azithromycin for the treatment of COVID-19. The intervention was defined as the treatment of COVID-19 with azithromycin, and for inclusion, in vivo studies needed to provide data allowing comparisons to be made between patients who did and did not receive azithromycin.
    keywords: azithromycin; covid-19; hydroxychloroquine; patients; studies; treatment
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        item: #965 of 7819
          id: cord-258725-z79gel8h
      author: Wood, R.
       title: Sharing a household with children and risk of COVID-19: a study of over 300,000 adults living in healthcare worker households in Scotland
        date: 2020-09-22
       words: 5320
      flesch: 45
     summary: For this fully adjusted analysis, the confidence interval included the null, and so was consistent with no beneficial effect of sharing a household with young children (HR per child 0.89; 95% CI 0.74-1.06). We found an inverse association between the number of young children in the household and risk of COVID-19 requiring hospitalisation in the part-time stratum (HR per child 0.63; 95% CI 0.43-0.92) but not in the whole time stratum (1.04; 95% CI 0.84-1.28, P-interaction = 0.007).
    keywords: adults; children; covid-19; household; license; medrxiv; preprint; sars
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        item: #966 of 7819
          id: cord-258757-vwfey8of
      author: Torres‐Navarro, I.
       title: Comment on ‘Two cases of COVID‐19 presenting with a clinical picture resembling chilblains: first report from the Middle East’: pernio unrelated to COVID‐19
        date: 2020-05-24
       words: 719
      flesch: 46
     summary: We read with interest the recent paper by Alramthan and Aldaraji in Clinical and Experimental Dermatology, contributing to the spectrum of COVID-19 clinical manifestations. Thus, we hypothesize that the increasing number of clinical cutaneous manifestations being reported are not caused directly by COVID-19, but are related to the globally imposed strict stay-at-home rules.
    keywords: covid-19; infection; pernio
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        item: #967 of 7819
          id: cord-258760-65dw8d5h
      author: Barr, Justin
       title: Surgeons, plague, and leadership: A historical mantle to carry forward
        date: 2020-05-05
       words: 698
      flesch: 37
     summary: Desperate to clarify its etiology, John Hunter, the father of scientific surgery, injected the purulent discharge from an infected patient's penis into his own member in an effort to understand the process of transmission and attempt to discriminate it from concomitant gonorrheal infection. Through his writings, this surgeon emerged as the contemporary authority on the condition, shaping scientific understanding of bubonic plague and medical responses to it for decades.
    keywords: plague; surgeons; surgery
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        item: #968 of 7819
          id: cord-258767-f6wrgn6z
      author: El-Khatib, Ziad
       title: The Association between Out-of-Pocket Expenditure and COVID-19 Mortality Globally
        date: 2020-09-17
       words: 769
      flesch: 43
     summary: We matched different datasets, through three steps: (i) matching the mortality by country with Growth Domestic Product (GDP); (ii) combining data of the Gini index of net income inequality within countries [11] ; and (iii) linking the data for each country health expenditure through out-of-pocket payments per capita in international dollars at purchasing power parity. The positive association of COVID-19 mortality with out-ofpocket expenditure underscores the challenges of COVID-19 mitigation in resource-limited countries.
    keywords: countries; covid-19; income
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        item: #969 of 7819
          id: cord-258817-9xzjlegx
      author: Zhang, Stephen X.
       title: At the height of the storm: Healthcare staff’s health conditions and job satisfaction and their associated predictors during the epidemic peak of COVID-19
        date: 2020-05-05
       words: 1207
      flesch: 49
     summary: Brain Behav Immun DOI: 10.1016/j.bbi.2020.05.010 sha: doc_id: 258817 cord_uid: 9xzjlegx This study reports the physical health, mental health, anxiety, depression, distress, and job satisfaction of healthcare staff in Iran when the country faced its highest number of total active COVID-19 cases. The predictors were also different from those identified in previous studies of healthcare staff during the COVID-19 crisis in China.
    keywords: covid-19; health; healthcare
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        item: #970 of 7819
          id: cord-258818-ys3ezzzz
      author: Galea, Sandro
       title: Understanding the Covid-19 pandemic through the lens of population health science
        date: 2020-07-15
       words: 3321
      flesch: 45
     summary: Building on our previously published work about the foundations of population health, we offer a few observations—a first draft of population health science thinking—as it intersects with the Covid-19 pandemic. Building on a frame of our previously published work about the foundations of population health, 1 we offer a few observations as a first draft of population health science thinking as it intersects the traumas of the moment, fully expecting that this work will evolve and improve in coming years.
    keywords: covid-19; health; pandemic; population; science
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        item: #971 of 7819
          id: cord-258832-0kyf7ikr
      author: Bullis, Sean S.M.
       title: A Cautionary Tale of False-Negative Nasopharyngeal COVID-19 Testing
        date: 2020-05-05
       words: 944
      flesch: 41
     summary: Possible explanations include improper collection or handling technique, viral load below the detectable limit of the assay, or diminished upper airway viral shedding. Based on these observations, the authors theorized a de-isolation protocol that not only considers date from symptom onset as is suggested by CDC (7), but also viral load.
    keywords: covid-19; negative
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        item: #972 of 7819
          id: cord-258841-n55qp6ov
      author: Baena-Díez, Jose Miguel
       title: Impact of COVID-19 outbreak by income: hitting hardest the most deprived
        date: 2020-08-07
       words: 2686
      flesch: 46
     summary: COVID-19 and the anti-lessons of history COVID-19 hospitalizations and deaths across Redefining vulnerability in the era of COVID-19 Socioeconomic deprivation, and hospitalization for COVID-19 in English participants of a national biobank Racial demographics and COVID-19 confirmed cases and deaths: a correlational analysis of 2886 US counties Research with older people in a world with COVID-19: identification of current and future priorities, challenges and opportunities Interactive Map of COVID-19 Cases Distribució territorial de la renda familiar disponible per càpita a Barcelona Informe sobre la situación de COVID-19 en España n • 26 Eurostat-your key to European statistics Public health emergency, health literacy and social panic: mapping of COVID-19 based on the web search data Geographic di erences in COVID-19 cases, deaths, and incidence -United States Combating COVID-19: health equity matters Impact of renal function on admission in COVID-19 patients: an analysis of the international HOPE COVID-19 (Health Outcome Predictive Evaluation for COVID 19) Registry Epidemiological and clinical characteristics of cases during the early phase of COVID-19 pandemic: a systematic review and meta-analysis Diabetes mellitus mortality in Spanish cities: trends and geographical inequalities Social, lifestyle and demographic inequalities in hypertension care Hospitalization and mortality among Black patients and White patients with Covid-19 European Strategies for Tackling Social Inequities in Health: Finally, the strong links between housing and health could also be contributing to inequalities in COVID-19 incidence and outcome.
    keywords: barcelona; cases; covid-19; district; health; incidence; income
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        item: #973 of 7819
          id: cord-258844-b4d79m1f
      author: Denning, M.
       title: DETERMINANTS OF BURNOUT AND OTHER ASPECTS OF PSYCHOLOGICAL WELL-BEING IN HEALTHCARE WORKERS DURING THE COVID-19 PANDEMIC: A MULTINATIONAL CROSS-SECTIONAL STUDY
        date: 2020-07-18
       words: 3796
      flesch: 43
     summary: Methods From 22nd March 2020 to 18th June 2020, healthcare workers from the United Kingdom, Poland, and Singapore were invited to participate using a self-administered questionnaire comprising the Safety Attitudes Questionnaire (SAQ), Oldenburg Burnout Inventory (OLBI) and Hospital Anxiety and Depression Scale (HADS) to evaluate safety culture, burnout and anxiety/depression. Conclusion Our findings demonstrate a significant burden of burnout, anxiety, and depression amongst healthcare workers.
    keywords: anxiety; attitudes; burnout; covid-19; depression; healthcare; safety; study; workers
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        item: #974 of 7819
          id: cord-258846-v6aaflzc
      author: Shruti, V.C.
       title: Reusable masks for COVID-19: A missing piece of the microplastic problem during the global health crisis
        date: 2020-10-20
       words: 3162
      flesch: 37
     summary: Reusable masks are presently excluded from microplastic surveys; as of now, the environmental impact of reusable masks is unknown and not scientifically documented. In just a matter of months, the use of reusable face masks is quite widespread among public and have quickly evolved as an essential public health item in the combat against the pandemic.
    keywords: covid-19; et al; face; masks; microfibers; pandemic; polyester
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        item: #975 of 7819
          id: cord-258855-2i51eyfq
      author: Korman, Tony M
       title: Early Outpatient Treatment of Symptomatic, High-Risk Covid-19 Patients
        date: 2020-07-20
       words: 580
      flesch: 28
     summary: Important First Step Hydroxychloroquine and azithromycin as a treatment of COVID19: results of an open-label non-randomized clinical trial Empirical evaluation of very large treatment effects of medical interventions Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France Empirical treatment with hydroxychloroquine and azithromycin for suspected cases of COVID-19 followed-up by telemedicine To all medical professionals around the world A Detailed Coronavirus Treatment Plan from Dr. Vladimir Zelenko. Unfortunately, based on laboratory and other preliminary evidence to-date, no treatment is available effective in preventing hospitalization for the overwhelming majority, and there are potential hazards associated with HCQ+AZ. Gautret et al. reported an open-label non-randomized study which showed a significant reduction of patients with detectable virus but included only six patients treated with HCQ+AZ and injudiciously recommended that COVID-19 patients be treated with HCQ+AZ to cure their infection and to limit the transmission of the virus.
    keywords: patients; treatment
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        item: #976 of 7819
          id: cord-258859-iaiosjlu
      author: Wang, Jiao
       title: Mask use during COVID-19: A risk adjusted strategy()
        date: 2020-06-25
       words: 2687
      flesch: 36
     summary: key: cord-258859-iaiosjlu authors: Wang, Jiao; Pan, Lijun; Tang, Song; Ji, John S.; Shi, Xiaoming title: Mask use during COVID-19: A risk adjusted strategy() date: 2020-06-25 journal: To achieve this goal, government should establish a risk adjusted strategy of mask use to scientifically publicize the use of masks, guarantee sufficient supply of masks, and cooperate for reducing health resources inequities.
    keywords: cases; coronavirus; covid-19; mask; pandemic; public; sars; use
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        item: #977 of 7819
          id: cord-258865-sxz39swi
      author: Rabbani, H.
       title: Modelling COVID-19 using the Fundamentals of Fluid Dynamics
        date: 2020-06-25
       words: 2248
      flesch: 46
     summary: The number of infected cases is given by Equation 1 where ∅ is the ratio of total infected cases I, Table 1 . . is the ratio of total number of infected cases at the initial phase of epidemic over the total number of initial susceptible people .
    keywords: cases; license; medrxiv; preprint
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        item: #978 of 7819
          id: cord-258873-l9oxmqdp
      author: Baker, D.
       title: COVID‐19 vaccine‐readiness for anti‐CD20‐depleting therapy in autoimmune diseases
        date: 2020-08-01
       words: 6044
      flesch: 37
     summary: As such, drug‐induced B cell subset inhibition, that controls at least some autoimmunities, would not influence innate and CD8 T cell responses, which are central to SARS‐CoV‐2 elimination, nor the hypercoagulation and innate inflammation causing severe morbidity. However, while B cell responses to a variety of different vaccines are clearly inhibited by CD20 depletion despite some inhibition of CD20 T cells [99, 113] , inactivated herpes zoster vaccine can at least induce T cell responses [114] .
    keywords: cell; cov-2; covid-19; ocrelizumab; patients; people; responses; rituximab; sars; sclerosis; treatment; vaccine
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        item: #979 of 7819
          id: cord-258877-6hy37qxa
      author: Dolgikh, S.
       title: Covid-19 vs BCG Universal Immunization: Statistical Significance at Six Months of Exposure
        date: 2020-09-08
       words: 3862
      flesch: 35
     summary: https://doi.org/10.1101/2020.09.06.20189423 doi: medRxiv preprint Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Further evidence of a Possible Correlation Between the Severity of Covid-19 and BCG Immunization Is global BCG vaccination-induced trained immunity relevant to the progression of SARS-CoV-2 pandemic? Mandated Bacillus Calmette-Guérin (BCG) vaccination predicts flattened curves for the spread of BCG vaccination policy and protection against COVID-19 Covid-19 vs BCG: Statistical significance analysis Whole blood profiling of bacillus Calmette-Guérin-induced trained innate immunity in infants identifies epidermal growth factor, IL-6, plate-let-derived growth factor-AB/BB, and natural killer cell activation Thirty years of BCG immunotherapy for non-muscle invasive bladder cancer: a success story with room for improvement Potential effect of age of BCG vaccination on global paediatric tuberculosis mortality: a modelling study The BCG World Atlas: A Database of Global BCG Vaccination Policies and Practices Canada Covid-19 situation update New York City Covid-19 Updates The BCG vaccine: information and recommendations for use in Australia, The Department of Health WHO immunization estimates Bacillus Calmette-Guérin (BCG) vaccination patterns in the province of BCG vaccination-induced emergency granulopoiesis provides rapid protection from neonatal sepsis Sex-based differences in susceptibility to Severe acute Respiratory Syndrome coronavirus infection Impact of BCG vaccination on incidence of tuberculosis disease in southern Ireland The null hypothesis in this case would dictate that immunization should carry no statistical significance for the epidemics impact, and therefore distributions in all of BCG group sample points (A, B, C) as defined above were described by a single distribution with, possibly, time-dependent parameters μ(t), σ(t) that can be estimated from the overall dataset.
    keywords: bcg; cases; correlation; hypothesis; impact; preprint; time
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        item: #980 of 7819
          id: cord-258879-dueab356
      author: Imran, Nazish
       title: Psychological impact of COVID-19 pandemic on postgraduate trainees: a cross-sectional survey
        date: 2020-08-25
       words: 3882
      flesch: 42
     summary: ► High psychological distress among postgraduate trainees during COVID-19 pandemic is reported in Pakistan. Our study contributes to literature on prevalence of psychological symptoms in postgraduate trainees.
    keywords: acute; anxiety; covid-19; depression; postgraduate; study; symptoms; trainees
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        item: #981 of 7819
          id: cord-258885-ev2pvr3s
      author: Werth, Annette
       title: Impact analysis of COVID-19 responses on energy grid dynamics in Europe
        date: 2020-10-22
       words: 4843
      flesch: 46
     summary: This procedure enabled a systematic determination of the interval of time to study how European countries modulated electrical energy generation, and transmission in order to balance for the reduced consumption. With this methodology, energy load, generation and international transmission were studied for 16 European countries, for which data were available, to understand how Europe's electric grid was affected by the epidemic.
    keywords: countries; country; covid-19; electricity; energy; generation; load; years
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        item: #982 of 7819
          id: cord-258888-amimzjee
      author: Ananth, Lakshmi
       title: Management of ENT Surgical Emergencies Amidst COVID-19 Lockdown: Our Experience in a Tertiary Referral Hospital
        date: 2020-07-23
       words: 3670
      flesch: 44
     summary: COVID-19 in India: potential impact of the lockdown and other longer-term policies The effects of the COVID-19/SARS-CoV-2 pandemic outbreak on otolaryngology activity in Italy Effect of COVID-19 related lockdown on ophthalmic practice and patient care in India: results of a survey Immediate and long term impact of the COVID 19 pandemic on delivery of surgical services ICMR: Revised Strategy of COVID19 testing in India Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China. Cancelling of routine OPDs and follow ups, discouraging of patients with non-emergency complaints from visiting the hospital, lack of availability of transport, inadequate testing facilities for asymptomatic patients and the fear of spread of infection to healthcare workers and other patients can all contribute to this.
    keywords: cases; covid-19; healthcare; hospital; infection; lockdown; patients; risk; testing
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        item: #983 of 7819
          id: cord-258891-iogn24iu
      author: Cabona, Corrado
       title: Epilepsy course during COVID-19 pandemic in three Italian epilepsy centers
        date: 2020-08-25
       words: 2524
      flesch: 39
     summary: To address the effect of COVID-19 pandemic on seizure incidence, data collection included the number of consultations for first seizures, relapse seizures, and status epilepticus (SE) in the emergency department of one of the participating centers. With the aim of managing epilepsy in quarantined patients, three Italian Epilepsy Centers set up telephone consultations using a semistructured interview, allowing a prospective collection of data on seizure course and other seizure-related problems during pandemic.
    keywords: covid-19; emergency; epilepsy; pandemic; patients; period; seizures
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        item: #984 of 7819
          id: cord-258895-bfosmipc
      author: Jalaber, Carole
       title: Role of upfront CT pulmonary angiography at admission in COVID-19 patients
        date: 2020-08-25
       words: 1160
      flesch: 38
     summary: From March 26 th , 2020, following the reports of frequent PE in COVID-19 patients (9, 10) , it was decided to systematically perform CTPA as first-line imaging modality in patients suspected of COVID-19 at xxxx (Blinded for review) University Hospital, unless there were contraindications to contrast medium administration. The Role of Chest Imaging in Patient Management during the COVID-19 Pandemic : A Multinational Consensus Statement from the Fleischner Society COVID-19 patients and the radiology department -advice from the European Society of Radiology (ESR) and the European Society of Thoracic Imaging (ESTI) Thromboinflammation and the hypercoagulability of COVID-19 Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Acute pulmonary embolism in COVID-19 patients on CT angiography and relationship to D-dimer levels Pulmonary embolism in patients with Covid-19 pneumonia Acute Pulmonary Embolism Associated with COVID-19 Pneumonia Detected by Pulmonary CT Angiography Acute pulmonary embolism and COVID-19 pneumonia : a random association?
    keywords: covid-19; patients; pulmonary
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        item: #985 of 7819
          id: cord-258905-0hgdtalg
      author: Bond, Katherine
       title: Evaluation of Serological Tests for SARS-CoV-2: Implications for Serology Testing in a Low-Prevalence Setting
        date: 2020-08-06
       words: 3669
      flesch: 37
     summary: The overall sensitivity for either IgA or IgG detection was 67.9% (95% CI, 59.4%-75.6%) and specificity was 72.8% (95% CI, 62.6%-81.6%) CONCLUSIONS: Performance characteristics for COVID-19 serological assays were generally lower than those reported by manufacturers.
    keywords: assay; cov-2; covid-19; igg; poct; samples; sars; testing
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        item: #986 of 7819
          id: cord-258916-jbdz1pk0
      author: Andreae, MH
       title: Data and Debriefing Observations on Healthcare Simulation to Prepare for the COVID-19 Pandemic: Healthcare Simulation for COVID-19
        date: 2020-07-15
       words: 2885
      flesch: 33
     summary: The first part of this scenario was conducted to provide another training opportunity for participants to cover key objectives presented in other simulation scenarios regarding team management in COVID-19 patients. [12] The same case was repeated with a different team leader and the group practiced the protocol that had been designed for COVID-19 patients for management of cardiac arrest.
    keywords: care; covid-19; participants; patient; room; simulation; team
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        item: #987 of 7819
          id: cord-258965-g47n531n
      author: Ekpenyong, Bernadine
       title: Assessment of Knowledge, Practice and Guidelines towards the Novel COVID-19 among Eye Care Practitioners in Nigeria–A Survey-Based Study
        date: 2020-07-16
       words: 4739
      flesch: 42
     summary: Coronaviruses and blood safety Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study SARS-CoV-2 may be related to conjunctivitis but not necessarily spread through the conjunctiva SARS-CoV-2 and conjunctiva Nigeria responds to COVID-19; first case detected in sub-Saharan Africa COVID-19 Nigeria. Notwithstanding, 43.2% were either not so confident or not at all confident attending to any patient during the lockdown while 54.6% also reported they were not so confident or not all confident attending to COVID-19 patient or those at risk of COVID-19.
    keywords: care; covid-19; ecps; eye; guidelines; knowledge; lockdown; nigeria; study; survey
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        item: #988 of 7819
          id: cord-258976-w2up63o9
      author: Steinberg, Eric
       title: In Young Adults with COVID-19, Obesity Is Associated with Adverse Outcomes
        date: 2020-06-15
       words: 1487
      flesch: 46
     summary: We sought to identify whether adverse outcomes are associated with obesity, particularly in COVID-19 patients 45 years and younger. Future studies examining the clinical characteristics and risk factors of COVID-19 patients across large, diverse populations will strengthen our understanding of this novel and complex disease.
    keywords: covid-19; obesity; patients
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        item: #989 of 7819
          id: cord-258991-mrs5j2ep
      author: Huang, Yeen
       title: Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: a web-based cross-sectional survey
        date: 2020-04-12
       words: 3077
      flesch: 49
     summary: key: cord-258991-mrs5j2ep authors: Huang, Yeen; Zhao, Ning title: Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: a web-based cross-sectional survey date: 2020-04-12 journal: Psychiatry Res DOI: 10.1016/j.psychres.2020.112954 sha: doc_id: 258991 cord_uid: mrs5j2ep China has been severely affected by Coronavirus Disease 2019(COVID-19) since December, 2019. Third, univariate and multivariate logistic regression models were performed to explore potential influence factors for GAD, depressive symptoms, and sleep quality during COVID-19 outbreak.
    keywords: covid-19; outbreak; sleep; symptoms
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        item: #990 of 7819
          id: cord-259014-kl31nvdm
      author: Binyamin, Y.
       title: Israel National Obstetric Anesthesia WhatsApp group as a communication tool, before and during the COVID-19 pandemic
        date: 2020-10-16
       words: 952
      flesch: 46
     summary: key: cord-259014-kl31nvdm authors: Binyamin, Y.; Weiniger, CF.; Heesen, P.; Orbach-Zinger, S.; Eidelman, L.; Ginosar, Y.; A.Ioscovich title: Israel National Obstetric Anesthesia WhatsApp group as a communication tool, before and during the COVID-19 pandemic date: 2020-10-16 journal: Int J Obstet Anesth DOI: 10.1016/j.ijoa.2020.10.001 sha: doc_id: 259014 cord_uid: kl31nvdm nan We would like to report our experience from the Israel National Obstetric Anesthesia WhatsApp group. 4, 5 In conclusion, we report that group members found the use of a professional WhatsApp group provides rapid useful clinical information, particularly in a crisis period such as the COVID-19 pandemic.
    keywords: covid-19; group; whatsapp
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        item: #991 of 7819
          id: cord-259033-op94wuy4
      author: Wendling, Daniel
       title: Can SARS-CoV-2 trigger reactive arthritis?
        date: 2020-10-27
       words: 1194
      flesch: 36
     summary: The fear of infection of patients with rheumatological disease, due to rheumatological disease itself but also and above all due to the possible use of immunomodulating treatments, was at the center of the discussions and raised the question of the appropriateness of maintaining this treatment in the absence of signs of infection [1] . A few cases of acute arthritis or dactylitis have been reported, some of which may be suggestive of reactive arthritis.
    keywords: arthritis; covid-19; disease
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        item: #992 of 7819
          id: cord-259052-m2mg4lf4
      author: Zhang, Lina
       title: In Reply
        date: 2020-05-11
       words: 655
      flesch: 25
     summary: Third, in mechanically ventilated COVID-19 patients, lung ultrasonography can comprehensively assess the potential of lung recruitment based on pulmonary lesions' uniformity and severity and the presence of dynamic air bronchograms and tidal recruitment. Lung ultrasonography also facilitates lung recruitment, based on qualitative or semiquantitative lung scores, to understand the condition, duration, and results of recruitment, avoid barotrauma, and adverse hemodynamic effect, and facilitate the titration of positive end-expiratory pressure.
    keywords: covid-19; lung
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        item: #993 of 7819
          id: cord-259073-dixskemz
      author: Ward, Christine F.
       title: Altered Mental Status as a Novel Initial Clinical Presentation for COVID-19 Infection in the Elderly
        date: 2020-05-15
       words: 2131
      flesch: 41
     summary: And, similar to the patients described in this brief report, a New York Times article citing physicians caring for COVID-19 patients also described patients presenting with confusion and AMS prior to developing a fever or respiratory illness We present four cases of elderly patients who developed altered mental status as their presenting symptom without associated fever or respiratory symptoms.
    keywords: covid-19; disease; patients; symptoms; virus
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        item: #994 of 7819
          id: cord-259077-ls4h8ht5
      author: Dehghani, Payam
       title: North American COVID-19 ST-segment elevation myocardial infarction (NACMI) registry: Rationale, design, and implications()
        date: 2020-05-16
       words: 3244
      flesch: 27
     summary: Understanding the natural history and appropriate management of COVID-19 patients presenting with ST elevation is essential to inform patient management decisions and protect healthcare workers. The multicenter NACMI registry will collect data regarding ST elevation on ECG in COVID-19 patients to determine the etiology and associated clinical outcomes.
    keywords: covid-19; data; elevation; nacmi; pandemic; patients; registry; stemi
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        item: #995 of 7819
          id: cord-259087-hckz3yk0
      author: Diago-Sempere, E.
       title: Evaluation of Convalescent Plasma versus Standard of Care for the Treatment of COVID-19 in Hospitalazed Patients: study protocol for a phase 2 randomized, open-label, controlled, multicenter trial
        date: 2020-08-04
       words: 7037
      flesch: 42
     summary: Likewise, it will stick to the recommendations given by the consensus documents of the scientific journals to improve reliability and value of medical research literature by promoting transparent and accurate reporting of clinical research studies. Here we present a summary of the rationale and justification for conducting a multicenter, randomized clinical trial of CP therapy in COVID-19 hospitalized patients.
    keywords: august; author; copyright holder; funder; license; medrxiv preprint; patients; peer; peer review; preprint; review; study; version
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        item: #996 of 7819
          id: cord-259106-nrg1960d
      author: Vasquez-Chavesta, Angie Z.
       title: COVID-19 and dengue: Pushing the peruvian health care system over the edge
        date: 2020-06-26
       words: 954
      flesch: 60
     summary: Additionally, several regions in northern Peru (Loreto, Lambayeque, Piura and La Libertad) not only have a considerable number of Dengue cases but are also in the Top 6 of COVID-19 cases. Although the number of deaths has not changed in the previous EW21 to EW23, the increase of Dengue cases is likely to become more evident in the next weeks or months.
    keywords: covid-19; dengue; health
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        item: #997 of 7819
          id: cord-259129-4dio8us0
      author: Zhang, S. X.
       title: Succumbing to the COVID-19 Pandemic: Healthcare Workers not Satisfied and Intend to Leave Their Jobs
        date: 2020-05-24
       words: 2497
      flesch: 57
     summary: For example, office days of healthcare workers negatively predicted job satisfaction for the young (e.g. at 25 years old: b=-0.21; 95% CI: -0.36 to -0.60) but positively predicted job satisfaction for the old (e.g. at 65 years old: b=0.25; 95% CI: 0.06 to 0.44). It is paramount for healthcare workers to feel satisfied with their jobs and lives during a pandemic.
    keywords: healthcare; job; preprint; satisfaction; workers
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        item: #998 of 7819
          id: cord-259140-5ik10en4
      author: Bianchetti, Angelo
       title: Clinical Presentation of COVID19 in Dementia Patients
        date: 2020-05-15
       words: 1225
      flesch: 46
     summary: In clinical series of patients who died of COVID-19 comorbidities (especially hypertension, cardiac ischemic disease, diabetes and obesity) were identified as significant risk factors for mortality, while dementia was described as a comorbid condition in only 6.8% of COVID-19 patients (2) . The diagnosis of dementia, especially in the most advanced stages, represents an important risk factor for mortality in COVID-19 patients.
    keywords: covid-19; dementia; patients
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        item: #999 of 7819
          id: cord-259178-2opfkm7l
      author: Gao, Ya
       title: Research Collaboration and Outcome Measures of Interventional Clinical Trial Protocols for COVID-19 in China
        date: 2020-09-02
       words: 2789
      flesch: 45
     summary: Recently, scholars have assessed the characteristics and status quo of registered COVID-19 clinical trials (9, 10) . This study was designed to evaluate the cooperation between institutions and the distribution of outcome measures in registered interventional clinical trials (ICTs) of COVID-19 conducted in China, to provide a reference for future researchers to register and carry out COVID-19 clinical trials.
    keywords: covid-19; icts; institutions; outcome; provinces; trials
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        item: #1000 of 7819
          id: cord-259181-g47n97tc
      author: Khan, Zahid Hussain
       title: Tests with proven value in diagnosis of COVID-19
        date: 2020-06-17
       words: 1130
      flesch: 42
     summary: (1) showed that the novel COVID-19 RdRp/Hel assay exhibited the highest sensitivity (Se) and specificity (Sp) for detection of SARS-CoV-2 RNA in vitro and in COVID-19 patient specimens. key: cord-259181-g47n97tc authors: Khan, Zahid Hussain; Samadi, Shahram; Makarem, Jalil; Mireskandari, Seyed Mohamad title: Tests with proven value in diagnosis of COVID-19 date: 2020-06-17 journal: Iran J Microbiol DOI: nan sha: doc_id: 259181 cord_uid: g47n97tc COVID-19 has literally ravaged the entire world.
    keywords: covid-19; diagnosis; tests
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        item: #1001 of 7819
          id: cord-259223-6b07qiw2
      author: Feitosa, Eduardo L
       title: COVID-19: Rational discovery of the therapeutic potential of Melatonin as a SARS-CoV-2 main Protease Inhibitor
        date: 2020-07-30
       words: 6859
      flesch: 34
     summary: In addition to its therapeutic properties on hyper-inflammation, oedema, immune dysregulation and possible sepsis in moderate-advanced stages of the disease, this drug may also be evaluated for its antiviral action in more recent stages of COVID-19 infection. WHO declares COVID-19 a pandemic Clinical course and mortality risk of severe COVID-19 Covid-19 -navigating the uncharted Covid-19: doctors are told not to perform CPR on patients in cardiac arrest A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 Case of the index patient who caused tertiary transmission of COVID-19 infection in Korea: the application of lopinavir/ ritonavir for the treatment of COVID-19 infected pneumonia monitored by quantitative RT-PCR Patients of COVID-19 may benefit from sustained lopinavir-combined regimen and the increase of eosinophil may predict the outcome of COVID-19 progression First clinical study using HCV protease inhibitor danoprevir to treat naive and experienced COVID-19 patients Lopinavir/ritonavir combination therapy amongst symptomatic coronavirus disease 2019 patients in India:
    keywords: binding; cells; complexes; coronavirus; covid-19; immune; infection; interaction; melatonin; mpro; patients; potential; protease; protein; results; sars; site; therapeutic; treatment
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        item: #1002 of 7819
          id: cord-259229-e8m8m4ut
      author: Samidurai, Arun
       title: Cardiovascular Complications Associated with COVID-19 and Potential Therapeutic Strategies
        date: 2020-09-16
       words: 10793
      flesch: 30
     summary: While the ACE2 gene is located on the X-chromosome, gender has an impact among COVID-19 patients, where men are at increased risk of susceptibility to COVID-19 infection and CVD complications due to their hemizygous allele for ACE2 compared to heterozygous allele in female [28] . Several promising therapeutics are under investigation to the overall prognosis of COVID-19 patients with high risk of cardiovascular impairment, nevertheless to date, none have shown proven clinical efficacy.
    keywords: ace2; acute; angiotensin; cardiac; cell; china; complications; coronavirus; cov-2; covid-19; covid-19 patients; disease; failure; heart; infection; mortality; patients; risk; sars; study; treatment; vaccine
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        item: #1003 of 7819
          id: cord-259244-svoakvic
      author: Soler, Zachary M.
       title: A primer on viral‐associated olfactory loss in the era of COVID‐19
        date: 2020-04-09
       words: 4331
      flesch: 45
     summary: key: cord-259244-svoakvic authors: Soler, Zachary M.; Patel, Zara M.; Turner, Justin H.; Holbrook, Eric H. title: A primer on viral‐associated olfactory loss in the era of COVID‐19 date: 2020-04-09 journal: Int Forum Allergy Rhinol DOI: 10.1002/alr.22578 sha: doc_id: 259244 cord_uid: svoakvic Early reports have suggested that smell loss may be an early symptom associated with the pandemic known as COVID‐19. Therefore, there is often a significant delay between onset of olfactory loss and presentation to a provider's office for evaluation, with one study documenting an average of 3 years between symptom onset and olfactory testing.
    keywords: associated; covid-19; infection; loss; olfactory; patients; smell; training
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        item: #1004 of 7819
          id: cord-259250-ybfyiykz
      author: Korem, Sindhuja
       title: Guillain-Barré syndrome associated with COVID-19 disease
        date: 2020-09-21
       words: 1978
      flesch: 47
     summary: Revue Neurologique Guillain-Barré syndrome following COVID-19: new infection, old complication? Guillain-Barré syndrome associated with SARS-CoV-2 infection: causality or coincidence? Evidence of the COVID-19 virus targeting the CNS: tissue distribution, Host-Virus interaction, and proposed neurotropic mechanisms Neurologic complications of COVID-19 Guillain Barre syndrome associated with COVID-19 infection: a case report is a need for further investigation into how COVID-19 is related to GBS.Contributors Contributions were collaboratively made by all authors. Our case had a typical course of viral symptoms preceding GBS findings.
    keywords: covid-19; gbs; guillain; symptoms; syndrome
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        item: #1005 of 7819
          id: cord-259257-yw3k8kr4
      author: Logar, Silvia
       title: Care home facilities as new COVID-19 hotspots: Lombardy Region (Italy) case study
        date: 2020-04-29
       words: 567
      flesch: 33
     summary: On March 30 2020, Lombardy Region passed a second Council Deliberation (n. XI / 3018) establishing further guidelines for the admission and care of care homes residents. Unprepared care homes have emerged as new COVID-19 hotspots, struggling to secure safe lockdown for elderly residents, at risk for severe and fatal SARS-CoV-2 infections.
    keywords: care; covid-19; rsa
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        item: #1006 of 7819
          id: cord-259267-trpo5w11
      author: Vilibic-Cavlek, Tatjana
       title: Severe acute respiratory syndrome coronavirus 2 seroprevalence among personnel in the healthcare facilities of Croatia, 2020
        date: 2020-08-26
       words: 1497
      flesch: 40
     summary: Statistical estimates of COVID-19 incidence indicated that the number of asymptomatic cases was significant 3 . participants reported contact with a confirmed COVID-19 patient, participation in large community events, and travelling to areas with documented COVID-19 transmission, respectively.
    keywords: cov-2; covid-19; hcws; healthcare; sars
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        item: #1007 of 7819
          id: cord-259269-hjmmn8xm
      author: Nattel, Stanley
       title: A Focus on Covid-19: Fast and Accurate Information to Guide Management for Pandemic-Related Issues in Cardiac Patients
        date: 2020-04-25
       words: 869
      flesch: 40
     summary: Areas covered include the use of renin-angiotensin system inhibitingagents in Covid-19 patients, special considerations in managing cardiac implanted electronic devices (CIEDs), guidance on extracorporeal membrane oxygenation (ECMO), cardiac procedures, and the distinction between Covid-19 pneumonia and heart failure. key: cord-259269-hjmmn8xm authors: Nattel, Stanley; Graham, Michelle; Krahn, Andrew title: A Focus on Covid-19:
    keywords: covid-19; pandemic; patients
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        item: #1008 of 7819
          id: cord-259271-4zj60pu8
      author: Moutray, Chad
       title: In recovery mode: manufacturers try to bounce back after COVID-19 disruptions
        date: 2020-10-20
       words: 4987
      flesch: 49
     summary: US manufacturing production declined 20.2% between February and April, and the sector lost 1,363,000 workers over that time frame, many temporarily furloughed due to shutdowns and reduced operations. 3 2 Severe disruptions in production, hiring and exports US manufacturing production fell abruptly and sharply between February and April, plunging 20.2% over that time frame (Table 1) .
    keywords: companies; covid-19; data; manufacturers; manufacturing; pandemic; production; quarter; sector; survey
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        item: #1009 of 7819
          id: cord-259281-4w1tyqw9
      author: Shah, Vishank Arun
       title: Acute Encephalopathy Is Associated With Worse Outcomes In COVID-19 Patients
        date: 2020-09-01
       words: 1439
      flesch: 39
     summary: We aimed to determine prevalence of acute encephalopathy in hospitalized patients and hypothesized that COVID-19 patients with acute encephalopathy are likely to have worse COVID-19 related outcomes. De-identified patient information for COVID-19 patients with and without acute encephalopathy were extracted using TriNetX, a global health collaborative clinical research platform collecting real-time electronic medical record data from a network of health care organizations across U.S.A. and some outside US territories.
    keywords: acute; covid-19; patients
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        item: #1010 of 7819
          id: cord-259288-eahhf7yh
      author: Lee, Elaine Y P
       title: COVID-19 pneumonia: what has CT taught us?
        date: 2020-04-30
       words: 1320
      flesch: 40
     summary: Shi and colleagues reported the presence of unilateral ground-glass opacities in a subgroup of 15 asymptomatic patients with COVID-19 pneumonia, substantiating previous anecdotal reports that asymptomatic patients could have CT changes before symptom onset. [4] [5] [6] Notably, in Shi and colleagues' study, the asymptomatic (subclinical) group of patients showed early CT changes, supporting what was fi rst observed in a familial cluster with COVID-19 pneumonia.
    keywords: covid-19; patients; pneumonia
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        item: #1011 of 7819
          id: cord-259306-3ldoo5ly
      author: Gillespie, Megan
       title: Coronavirus Disease 2019 (COVID-19) Complicated by Spontaneous Pneumomediastinum and Pneumothorax
        date: 2020-09-23
       words: 806
      flesch: 27
     summary: Providers should be familiar with both typical symptoms and image study results for COVID-19 as well as less commonly reported complications of progressive COVID-19, such as spontaneous pneumomediastinum and spontaneous pneumothorax as highlighted in this case. Providers should be familiar with both typical symptoms and image study results for COVID-19 as well as less commonly reported complications of progressive COVID-19, such as spontaneous pneumomediastinum and spontaneous pneumothorax as highlighted in this case.
    keywords: coronavirus; covid-19
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        item: #1012 of 7819
          id: cord-259311-ccx61owl
      author: Kapitula, D. S.
       title: Performance & Quality Evaluation of Marketed COVID-19 RNA Detection Kits
        date: 2020-05-01
       words: 3189
      flesch: 47
     summary: In conclusion, Jade Biomedical (Suzhou) Co, Ltd has identified the Best Total Solution (BTS) for COVID-19 RNA testing, which involves using Tiangen or Qiagen RNA extraction and BGI qPCR kits. Notably, the initial failure in quality virus testing kits distributed by US CDC is viewed as a critical mistake in the management of the crises by the US government resulting in compromised ability to test and trace the earlier infected population clusters before they spread to wider populations through community contacts.
    keywords: china; covid-19; detection; kits; performance; rna; table; testing; virus
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        item: #1013 of 7819
          id: cord-259327-6hessuhh
      author: Agius, Raymond
       title: Disease and death from work: RIDDOR and covid-19
        date: 2020-09-14
       words: 1518
      flesch: 44
     summary: Yet HSE guidance seeks to limit reporting to deaths where covid-19 as a cause must have been 'significant' [3] -a word which only appears in Part II of the death certificate [13] . Substantial undercounting arises from the HSE guidance quite categorically excluding notification of covid-19 cases in workers
    keywords: cases; covid-19; guidance; hse
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        item: #1014 of 7819
          id: cord-259329-8pta6o6a
      author: Haimovich, Adrian
       title: Development and validation of the quick COVID-19 severity index (qCSI): a prognostic tool for early clinical decompensation
        date: 2020-07-21
       words: 4827
      flesch: 38
     summary: 7, 8 Given the high morbidity and mortality associated with COVID-19 and uncertainty around the disease process and prognosis, there is great urgency in developing and validating effective clinical risk stratification tools for COVID-19 patients. In a large cohort of COVID-19 patients, severe and critical illness represented almost 20% of the studied population.
    keywords: cohort; covid-19; data; hours; illness; model; patients; qcsi; risk; system; validation; values
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        item: #1015 of 7819
          id: cord-259331-hi6gyp52
      author: Malhotra, Ajay
       title: COVID-19 Initial Impact on Radiology Practices: Survey from ACR/RBMA
        date: 2020-08-04
       words: 2014
      flesch: 47
     summary: Radiology practice volumes were reported to be increasing recently. The coronavirus disease 2019 (COVID-19) impacted radiology practices in many ways.
    keywords: imaging; practices; radiology; volumes
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        item: #1016 of 7819
          id: cord-259338-q3kw6n9o
      author: Jean, Sim Xiang Ying
       title: Utilizing the Electronic Health Records to Create a Syndromic Staff Surveillance System During the COVID-19 outbreak
        date: 2020-11-04
       words: 2565
      flesch: 43
     summary: World Health Organisation Coronavirus disease (COVID-19) Pandemic Containment of COVID-19 cases among healthcare workers: The role of surveillance, early detection, and outbreak management Healthcare workers in Singapore infected with COVID-19 Monitoring approaches for health-care workers during the COVID-19 pandemic Use of a Real-Time Locating System for Contact Tracing of Health Care Workers During the COVID-19 Pandemic at an Infectious Disease Center in Singapore: Validation Study Responding to the COVID-19 outbreak in Singapore: Staff protection and staff temperature and sickness surveillance systems Overview of sentinel systems for hospitalized severe acute respiratory infections (SARI) represented in the weekly EuroFlu surveillance bulletin COVID-19 and the gastrointestinal tract: more than meets the eye Emergency department syndromic surveillance providing early warning of seasonal respiratory activity in England Syndromic surveillance for local outbreaks of lower-respiratory infections: would it work Reduction in healthcare-associated respiratory viral infections during a COVID-19 outbreak Our team would like to acknowledge all staff within the institution who have contributed in COVID-19 pandemic efforts. Our study demonstrates the feasibility in utilizing the EHR in the detection of ARI clusters amongst hospital staff.
    keywords: ari; clusters; covid-19; infection; staff; surveillance; system
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        item: #1017 of 7819
          id: cord-259358-p6ov2r6g
      author: Horii, Toshihiro
       title: Late-onset pneumothorax in a COVID-19 patient treated with ventilation and ECMO: A case report and literature review
        date: 2020-09-23
       words: 1528
      flesch: 41
     summary: The occurrence of pneumothorax in COVID-19 patients is not common, and there have been only a few previous reports. To our knowledge, five previous case reports of pneumothorax in COVID-19 patients have been published to date [9] [10] [11]
    keywords: case; covid-19; patients; pneumothorax
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        item: #1018 of 7819
          id: cord-259426-qbolo3k3
      author: Tadesse, Trhas
       title: Predictors of Coronavirus Disease 2019 (COVID-19) Prevention Practices Using Health Belief Model Among Employees in Addis Ababa, Ethiopia, 2020
        date: 2020-10-22
       words: 5286
      flesch: 50
     summary: COVID-19 prevention practices: Practice of COVID-19 prevention was measured using eleven questions. Therefore, this study investigated the predictors of COVID-19 prevention practice using the Health Belief Model among employees in Addis Ababa, Ethiopia, 2020.
    keywords: covid-19; employees; health; knowledge; level; model; practice; prevention; study
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        item: #1019 of 7819
          id: cord-259448-deya8dwn
      author: Li, Caixia
       title: Differential microRNA expression in the peripheral blood from human patients with COVID‐19
        date: 2020-09-22
       words: 2662
      flesch: 53
     summary: The coronavirus disease (COVID‐19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which play important roles in regulating gene expression and are also considered as essential modulators during viral infection. Existing evidence suggests that miRNAs play critical roles in regulating gene expression by targeting the mRNAs of protein-coding genes.
    keywords: covid-19; expression; genes; hsa; mirnas; patients
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        item: #1020 of 7819
          id: cord-259481-og7n82fl
      author: Zhang, Hai-tao
       title: Automated detection and quantification of COVID-19 pneumonia: CT imaging analysis by a deep learning-based software
        date: 2020-07-14
       words: 2919
      flesch: 48
     summary: Chest CT combined with analysis by the uAI Intelligent Assistant Analysis System can accurately evaluate pneumonia in COVID-19 patients. Radiological examinations, especially thin slice chest Computed tomography (CT) scans, play an important role in identifying the early phase of lung infection, monitoring disease progression and guiding clinical decision making for COVID-19 patients [5, 7, 8] .
    keywords: covid-19; infection; lobe; lung; patients; segment
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        item: #1021 of 7819
          id: cord-259523-92hz534s
      author: Pullen, Lara C.
       title: COVID‐19: transplant works toward adaptation
        date: 2020-09-29
       words: 1642
      flesch: 46
     summary: As the potential for donor-derived COVID-19 infection is not understood, transplant centers and organizations err on the side of caution. Thus, transplant centers and organ procurement organizations apply the precautionary principle and look to small studies of SARS-CoV-2 as well as studies of related coronaviruses for guidance.
    keywords: cov-2; covid-19; sars; transplant
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        item: #1022 of 7819
          id: cord-259540-e7xt6pck
      author: Wang, Guan
       title: Description of COVID‐19 cases along with the measures taken on prevention and control in Zhejiang, China
        date: 2020-05-22
       words: 1879
      flesch: 49
     summary: 3, 12 Along with national actions against the disease, the Zhejiang government has also taken emergency measures to control the outbreak of disease, such as application of big data for monitoring the health status of citizens, 13 and development of nucleic acid detection kit for the early detection of COVID-19 cases. What is Health Code? Description of COVID-19 cases along with the measures taken on prevention
    keywords: cases; coronavirus; covid-19; disease; zhejiang
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        item: #1023 of 7819
          id: cord-259562-e1htl489
      author: Petzold, Moritz Bruno
       title: Risk, resilience, psychological distress, and anxiety at the beginning of the COVID‐19 pandemic in Germany
        date: 2020-07-07
       words: 3510
      flesch: 44
     summary: Interestingly, personal experiences with COVID-19 were not strongly connected to COVID-19 anxiety. This is undermined by our finding that self-efficacy (meaning a person's believe in his or her own ability to master situations or show a certain behavior) showed essential significant negative correlations with COVID-19 anxiety.
    keywords: anxiety; covid-19; distress; pandemic; participants; sample; study
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        item: #1024 of 7819
          id: cord-259566-qtlq7a6l
      author: Guraya, Salman Yousuf
       title: Transforming laparoendoscopic surgical protocols during COVID-19 pandemic; big data analytics, resource allocation and operational considerations; a review article
        date: 2020-06-23
       words: 2424
      flesch: 34
     summary: Regrettably, despite this profound work, so far we have neither succeeded in drawing a unified contingency management protocol nor a vaccine for combating COVID-19 disease. Parallel with the evolving guidelines for combating COVID-19 outbreak in medical field, several international surgical societies and regulatory bodies have adopted a host of surgical protocols.
    keywords: covid-19; disease; pandemic; patients; procedures; sars; surgery; transmission
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        item: #1025 of 7819
          id: cord-259605-6qa17pfb
      author: Coleman, Julia R.
       title: Maintaining Trauma Care Access During the COVID-19 Pandemic: An Urban, Level-1 Trauma Center's Experience
        date: 2020-05-01
       words: 1244
      flesch: 39
     summary: Urban, Level-1 trauma centers are uniquely poised to be command centers for trauma care. DHMC is dedicated to maintaining a state of readiness, including access to the operating room (OR), intensive care unit (ICU), and the full complement of trauma center resources.
    keywords: care; covid-19; patients; risk; trauma
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        item: #1026 of 7819
          id: cord-259611-q7ksx47g
      author: Mulanda Aura, Christopher
       title: Consequences of calamities and their management: the case of COVID-19 pandemic and flooding on inland capture fisheries in Kenya
        date: 2020-09-15
       words: 5104
      flesch: 47
     summary: Lake fisheries in are important sources of livelihood providing food and employment (Kimani et al., 2018) . Some biological aspects and life history strategies of Nile tilapia Oreochromis niloticus (L.) in Lake Victoria Habitat degradation and changes in Lake Victoria fisheries A century of change : Induced revolution of Lake Victoria fisheries and ecology Impact of Short-Term Flooding on Livelihoods in the Kenya Rift Valley Lakes in Spatial-temporal dynamics of water hyacinth,Eichhornia crassipes(Mart.), other macrophytes and their impact onfisheries in Lake Victoria Management implications of the response of two tilapiine cichlids to long-term changes in lake level, diversity and exploitation in an equatorial lake R: A language and environment for statistical computing.
    keywords: covid-19; data; et al; fisheries; fishing; flooding; kenya; lake; pandemic; study; victoria; water
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        item: #1027 of 7819
          id: cord-259618-kl0aq0ut
      author: De Leo, Diego
       title: The fight against COVID-19: a report from the Italian trenches
        date: 2020-04-20
       words: 2509
      flesch: 48
     summary: A discrepancy between the gift of a long life and public acceptance of older adults is increasingly noticeable and clearly expressed by the deprecated document on damages caused by longevity, which Christine Lagarde (now the president of the European Central Bank) spoke about a few years ago (2012): Old people live too long and this is a risk for the global economy. Those Tickets in Front of the House Telecommunication and suicide prevention: hopes and challenges for the new century Presentation of the Global Financial Stability Report The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients The value of maintaining social connections for mental health in older people
    keywords: care; covid-19; health; italy; patients; people
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        item: #1028 of 7819
          id: cord-259619-sco0d5cc
      author: Ludvigsson, Johnny
       title: Corona Pandemic: Assisted Isolation and Care to Protect Vulnerable Populations May Allow Us to Shorten the Universal Lock-Down and Gradually Re-open Society
        date: 2020-09-30
       words: 2499
      flesch: 43
     summary: We suggest here that more selective assisted isolation of vulnerable populations would reduce the predictable increase in hospital admissions and more rapidly alleviate the fallout from total lockdown measures. Sweden has used a policy rather similar to our recommendations to protect vulnerable groups, without a Frontiers in Public Health | www.frontiersin.org total lock-down of the society.
    keywords: care; countries; covid-19; health; measures; people; virus
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        item: #1029 of 7819
          id: cord-259660-x9sobzyw
      author: Mohakud, Nirmal K
       title: An Assumed Vertical Transmission of SARS-CoV-2 During Pregnancy: A Case Report and Review of Literature
        date: 2020-09-26
       words: 1436
      flesch: 54
     summary: The authors of one study described that three newborns born to mothers with COVID-19 infection had positive antibodies (IgM and IgG) at birth Our report shows that COVID-19 infection may possibly get transmitted vertically to the fetus.
    keywords: case; covid-19; hours; transmission
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        item: #1030 of 7819
          id: cord-259668-nwezszhj
      author: Ortiz, Alberto
       title: Complement and protection from tissue injury in COVID-19
        date: 2020-10-04
       words: 2622
      flesch: 32
     summary: The case of complement activation in COVID-19 multiorgan impact COVID-19, microangiopathy, hemostatic activation, and complement COVID-19: complement, coagulation, and collateral damage Rationale for targeting complement in COVID-19 Risk factors for severity of COVID-19 in chronic dialysis patients from a multicenter French cohort Validation of distinct pathogenic patterns in a cohort of membranoproliferative glomerulonephritis patients by cluster analysis Cluster analysis identifies distinct pathogenetic patterns in C3 glomerulopathies/ immune complex-mediated membranoproliferative GN Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis Increased complement receptor-3 levels in monocytes and granulocytes distinguish COVID-19 patients with pneumonia from those with mild symptoms Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis Renal artery thrombosis induced by coronavirus disease 2019 Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection Abnormal immunity of nonsurvivors with COVID-19: predictors for mortality The first case of COVID-19 treated with the complement C3 inhibitor AMY-101 Combination of ruxolitinib and eculizumab for treatment of severe SARS-CoV-2-related acute respiratory distress syndrome: a controlled study Eculizumab treatment in patients with COVID-19: preliminary results from real life ASL Napoli 2 While complement components are not usually assessed in routine care of COVID-19 patients, as illustrated by a recent detailed report of risk factors for severity of in chronic dialysis patients [10] , Prendecki et al.
    keywords: activation; complement; covid-19; disease; eculizumab; injury; patients
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        item: #1031 of 7819
          id: cord-259673-z7kvf8n8
      author: Rogerson, Stephen J.
       title: Identifying and combating the impacts of COVID-19 on malaria
        date: 2020-07-30
       words: 4070
      flesch: 38
     summary: World Health Organization Spread of artemisinin resistance in Plasmodium falciparum malaria Evolution and expansion of multidrug-resistant malaria in Southeast Asia: a genomic epidemiology study Determinants of dihydroartemisinin-piperaquine treatment failure in Plasmodium falciparum malaria in Cambodia, Thailand, and Vietnam: a prospective clinical, pharmacological, and genetic study The antimalarial pipeline Malaria elimination in remote communities requires integration of malaria control activities into general health care: an observational study and interrupted time series analysis in Myanmar Signatories from c. COVID-19 and risks to the supply and quality of tests, drugs, and vaccines Demand for coronavirus tests raises concerns over HIV and malaria The Guardian Novel coronavirus disease (COVID-19) mitigation steps provide a blueprint for malaria control and elimination Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial Civil Society for Malaria Elimination Nonessential research in the new normal: the impact of novel coronavirus disease (COVID-19) From aspiration to action: what will it take to end malaria? Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations The ACREME Investigators who contributed to this article include Prof Nicholas Anstey, Menzies School Authors' contributions SJR and JGB conceived the article. Recent successes in malaria control and elimination have reduced the global malaria burden, but these gains are fragile and progress has stalled in the past 5 years.
    keywords: control; countries; covid-19; elimination; health; malaria; programmes; treatment; world
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        item: #1032 of 7819
          id: cord-259691-3bo4md44
      author: Zhao, Ming
       title: Cytokine storm and immunomodulatory therapy in COVID-19: role of chloroquine and anti-IL-6 monoclonal antibodies
        date: 2020-04-16
       words: 1236
      flesch: 34
     summary: Trial Version 7) Breakthrough: chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19? Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology COVID-19: consider cytokine storm syndromes and immunosuppression Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Effective treatment of severe COVID-19 patients with tocilizumab Immunotherapeutic implications of IL-6 blockade for cytokine storm Clinical characteristics of influenza virus infection in juvenile idiopathic arthritis patients treated with tocilizumab Serious infection across biologic-treated patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis Comprehensive treatment and management of corona virus disease 2019: This study, which included 201 patients with COVID-19, found that treatment with methylprednisolone decreased the risk of death (hazard ratio 0.38, 95% confidence interval 0.20-0.72) among patients with acute respiratory distress syndrome (ARDS).
    keywords: covid-19; il-6; patients; treatment
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        item: #1033 of 7819
          id: cord-259699-48jg7ci7
      author: González-Calatayud, Dra Mariel
       title: Observational study of the suspected or confirmed cases of sars COV-2 infection needing emergency surgical intervention during the first months of the pandemic in a third level hospital: Case series
        date: 2020-10-24
       words: 2798
      flesch: 38
     summary: Discharge was indicated because of patient improvement in 23 cases (54.8%), death in 18 cases (42.9%), and 1 case is still hospitalized (2.4%) This can be explained because many of the General Surgery patients, in addition to their infectious process by COVID-19, had another complication, like sepsis, In the same way, we can say that pregnant patients are healthy and have a physiological condition.
    keywords: cases; covid-19; mortality; patients; sars; surgery
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        item: #1034 of 7819
          id: cord-259747-sl9q63oc
      author: Remmelink, Myriam
       title: Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients
        date: 2020-08-12
       words: 4549
      flesch: 43
     summary: key: cord-259747-sl9q63oc authors: Remmelink, Myriam; De Mendonça, Ricardo; D’Haene, Nicky; De Clercq, Sarah; Verocq, Camille; Lebrun, Laetitia; Lavis, Philomène; Racu, Marie-Lucie; Trépant, Anne-Laure; Maris, Calliope; Rorive, Sandrine; Goffard, Jean-Christophe; De Witte, Olivier; Peluso, Lorenzo; Vincent, Jean-Louis; Decaestecker, Christine; Taccone, Fabio Silvio; Salmon, Isabelle title: Unspecific post-mortem findings despite multiorgan viral spread in COVID-19 patients date: 2020-08-12 journal: Crit Care DOI: 10.1186/s13054-020-03218-5 sha: doc_id: 259747 cord_uid: sl9q63oc BACKGROUND: Post-mortem studies can provide important information for understanding new diseases and small autopsy case series have already reported different findings in COVID-19 patients. Most of the previous post-mortem studies in COVID-19 patients were conducted using needle biopsies and were therefore rather limited in terms of sampling; our complete autopsy analysis identified considerable heterogeneity of SARS-CoV-2 spread through the human body and provides a more accurate description of macroscopic and microscopic organ alterations.
    keywords: acute; covid-19; findings; lung; organs; patients; pcr; samples; sars; study
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        item: #1035 of 7819
          id: cord-259793-pue0mv99
      author: Shamshiripour, Ali
       title: How is COVID-19 reshaping activity-travel behavior? Evidence from a comprehensive survey in Chicago
        date: 2020-09-06
       words: 7750
      flesch: 46
     summary: The authors observed that the outbreak had greatly affected people's life, work, and travel behavior. Highlighting the influence of lifestyles on travel behavior during an outbreak, the authors found that although the frequency of these international trips reduced for all countries, the level of risk was perceived differently among those countries.
    keywords: behavior; covid-19; fig; future; home; online; pandemic; people; respondents; results; shopping; travel
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        item: #1036 of 7819
          id: cord-259808-82drb14x
      author: Andrews, Paul L R
       title: COVID‐19, nausea, and vomiting
        date: 2020-10-05
       words: 7934
      flesch: 34
     summary: Patients with digestive tract symptoms, including nausea, vomiting, and diarrhea, may have delayed hospital admission and a worse clinical outcome than those without. It has been argued 3 that the value of diarrhea as a clinical symptom in the diagnosis and spread of COVID-19 may be underestimated, particularly as digestive tract symptoms may precede respiratory ones.
    keywords: ace2; cells; coronavirus; cov-2; covid-19; diarrhea; incidence; infection; nausea; patients; sars; studies; symptoms; tract; vomiting
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        item: #1037 of 7819
          id: cord-259814-3x234ck2
      author: Giussani, Carlo
       title: The response during a pandemic is a blurred vision of the future. Reflections on the Lombardy reorganization of the neurosurgical emergencies during the COVID-19
        date: 2020-04-21
       words: 733
      flesch: 34
     summary: In the post-COVID-19 period, a reduction of the hubs for neurosurgical emergency, probably hypertrophic before the pandemic, is desirable but the correct identification of them, not only based on geographical criteria or political considerations, should be integrated by an evaluation that considers: Reflections on the Lombardy reorganization of the neurosurgical emergencies during the COVID-19 date: 2020-04-21 journal: Acta Neurochir (Wien) DOI: 10.1007/s00701-020-04327-4 sha: doc_id: 259814 cord_uid: 3x234ck2 nan We read with interest the editorial of Zoia and colleagues about the reorganization of neurosurgical activities, both elective and urgent, to face the COVID-19 outbreak and the viewpoint summarizing the actual situation.
    keywords: covid-19; pandemic; volume
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        item: #1038 of 7819
          id: cord-259837-5tbdqzxr
      author: Kalcioglu, Mahmut Tayyar
       title: May COVID-19 cause sudden sensorineural hearing loss?
        date: 2020-09-29
       words: 519
      flesch: 45
     summary: key: cord-259837-5tbdqzxr authors: Kalcioglu, Mahmut Tayyar; Cag, Yasemin; Kilic, Osman; Tuysuz, Ozan title: May COVID-19 cause sudden sensorineural hearing loss? date: 2020-09-29 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.09.1468 sha: doc_id: 259837 cord_uid: 5tbdqzxr nan We thank to Pietro D L et al for their comments on our recently published article (Kilic et al., 2020) . In previous studies, viral infections have been reported to have an important role in the etiology of sudden sensorineural hearing loss (SSNHL) (Cohen et al., 2014) .
    keywords: covid-19
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        item: #1039 of 7819
          id: cord-259869-kwzsdhrr
      author: Baghizadeh Fini, Maryam
       title: Oral saliva and CVID-19
        date: 2020-05-27
       words: 2443
      flesch: 43
     summary: Huge saliva droplets with more mass typically fall to the ground ballistically and small saliva droplets fly by airflow like a cloud over longer distances. When speaking, coughing, sneezing, or even breathing, saliva droplets are produced and shaped as particles in a combination of moisture and droplet nuclei of microorganisms.
    keywords: cov-2; covid-19; droplets; saliva; salivary; sars
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        item: #1040 of 7819
          id: cord-259871-46al6phc
      author: Weill, Joakim A.
       title: Social distancing responses to COVID-19 emergency declarations strongly differentiated by income
        date: 2020-08-18
       words: 2556
      flesch: 43
     summary: key: cord-259871-46al6phc authors: Weill, Joakim A.; Stigler, Matthieu; Deschenes, Olivier; Springborn, Michael R. title: Social distancing responses to COVID-19 emergency declarations strongly differentiated by income date: 2020-08-18 journal: Proc Natl Acad Sci U S A DOI: 10.1073/pnas.2009412117 sha: doc_id: 259871 cord_uid: 46al6phc In the absence of a vaccine, social distancing measures are one of the primary tools to reduce the transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, which causes coronavirus disease 2019 (COVID-19). In this paper, we use anonymized location pings data from mobile devices covering the entire United States to provide direct evidence of systematic differences in social distancing behavior across income levels during the COVID-19 pandemic.
    keywords: covid-19; data; distancing; emergency; income; measures; mobility; state
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        item: #1041 of 7819
          id: cord-259905-msefg1ww
      author: DA SILVA, MICHAEL
       title: COVID-19 and Health-Related Authority Allocation Puzzles
        date: 2020-06-08
       words: 6165
      flesch: 43
     summary: I am, for instance, moved by distributive justice concerns suggesting that federal authorities are best-placed to distribute scarce resources and epistemic concerns suggesting that cities may be best-placed to make decisions about how to allocate them-and even democratic accountability concerns related to the break between the number of city-dwellers impacted by the pandemic and the number of representatives that they have in federal or state governments managing responses. For a media report on one of the more controversial claims to federal authority, see Mazza E. Jared Kushner ripped for saying 'Our Stockpile' isn't meant for states to use.
    keywords: allocation; authority; cities; covid-19; federal; health; healthcare; powers; principles; state
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        item: #1042 of 7819
          id: cord-259906-9em5tjya
      author: Park, Ji Young
       title: First Pediatric Case of Coronavirus Disease 2019 in Korea
        date: 2020-03-16
       words: 1970
      flesch: 55
     summary: Most of the COVID-19 cases in children resulted from close contacts with COVID-19 cases or were found among family cluster cases. Meanwhile, the role of innate immunity to respiratory tract infection is greater in early life because the adaptive immune response is underdeveloped in young children.
    keywords: cases; children; coronavirus; covid-19; disease
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        item: #1043 of 7819
          id: cord-259924-a14svuwu
      author: Kavčič, Tina
       title: Psychological Functioning of Slovene Adults during the COVID-19 Pandemic: Does Resilience Matter?
        date: 2020-06-17
       words: 3832
      flesch: 37
     summary: We aspired to broaden existing knowledge on psychological functioning during such public health crises by focusing not only on mental health problems (i.e. stress levels) but also on positive mental health, thus adopting the modern view of mental illness and mental health as separate though related entities The aim of the present study was to investigate the buffering role of personal resilience in two aspects of psychological functioning, mental health and stress, among Slovene adults at the beginning of the COVID-19 outbreak.
    keywords: covid-19; functioning; health; pandemic; psychological; resilience; stress
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        item: #1044 of 7819
          id: cord-259952-58q4ma92
      author: Ganson, Kyle T.
       title: Associations between Anxiety and Depression Symptoms and Medical Care Avoidance during COVID-19
        date: 2020-09-01
       words: 960
      flesch: 47
     summary: Our results provide support for accurate and effective translation of knowledge to the public about the risks and benefits of seeking needed medical care during the ongoing COVID-19 pandemic. The lack of health care utilization is concerning as it may result in significant medical complications resulting from untreated medical problems.
    keywords: care; coronavirus; covid-19
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        item: #1045 of 7819
          id: cord-259971-e3h8pr1v
      author: Nwachukwu, Izu
       title: COVID-19 Pandemic: Age-Related Differences in Measures of Stress, Anxiety and Depression in Canada
        date: 2020-09-01
       words: 3994
      flesch: 43
     summary: In the severe acute respiratory syndrome (SARS) outbreak in Taiwan during late April to mid-May 2003, a relationship between age and the development of psychological symptoms was reported, with younger age groups at higher risk This was a cross-sectional survey exploring the mean differences of perceived stress, anxiety, and depression symptom scores among subscribers of various age categories who enrolled in the Text4Hope program.
    keywords: age; anxiety; covid-19; depression; pandemic; scores; stress; years
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        item: #1046 of 7819
          id: cord-259984-csdf1a69
      author: Raffiq, Azman
       title: COVID-19 Pandemic and Its Impact on Neurosurgery Practice in Malaysia: Academic Insights, Clinical Experience and Protocols from March till August 2020
        date: 2020-10-27
       words: 16405
      flesch: 43
     summary: Clinical guide for the management of paediatric neurosurgery patients during the coronavirus pandemic Early lessons in the management of COVID-19 for the pediatric neurosurgical community from the leadership of the American Society of Pediatric Neurosurgeons Anaesthesia and sars Infographic for principles of airway management in COVID-19 World Federation of Societies of Anesthesiologists This publication is not a proposed National guideline for the COVID-19 Management of COVID-19 neurosurgical patients but a review of management and protocols from local and international peer reviewed and non-peer reviewed publications, web-based information and data until the month of August 2020. It is imperative to balance the requirements of caring for COVID-19 patients with imminent risk of delay to others who need care.
    keywords: airway; care; cases; covid-19; disease; emergency; health; hospital; icu; malaysia; management; medical; non; pandemic; patients; ppe; procedures; resources; risk; room; services; staff; stroke; surgery; team; treatment; use; ventilation
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        item: #1047 of 7819
          id: cord-260002-hszdk4es
      author: Wayne, Annie S
       title: Cataloguing the response by emergency veterinary hospitals during the COVID‐19 pandemic via weekly surveys
        date: 2020-06-29
       words: 951
      flesch: 44
     summary: key: cord-260002-hszdk4es authors: Wayne, Annie S; Rozanski, Elizabeth A title: Cataloguing the response by emergency veterinary hospitals during the COVID‐19 pandemic via weekly surveys date: 2020-06-29 journal: J Vet Emerg Crit Care (San Antonio) DOI: 10.1111/vec.12974 sha: doc_id: 260002 cord_uid: hszdk4es BACKGROUND: The COVID‐19 pandemic has presented veterinary emergency hospitals with unique challenges.
    keywords: covid-19; hospitals; veterinary
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        item: #1048 of 7819
          id: cord-260033-9cv4eqp8
      author: Al Barbarawi, Mohammed M.
       title: The impact of COVID-19 on the neurosurgery practice in the North of Jordan
        date: 2020-06-04
       words: 515
      flesch: 27
     summary: The following situations have been considered as neurological emergencies: traumatic brain injury (moderate to severe traumatic brain injuries ,traumatic brain injury associated with other injuries , extreme age groups ), spine trauma (unstable fractures , neurological or sphincter deficits) intracranial bleedings (any type of bleeding was admitted), congenital anomalies(newborns with congenital myelomeningocele), hydrocephalus(shunt malfunction), and infections (brain abscess ,spondylodiscitis ,shunt infection and post operation wound infection) while traumatic brain injury such as concussion , admission depending on many factors like age and other associated injuries, also superficial post operation wound infection was treated with oral antibiotics with regular follow up in the Emergency department . We hope that COVID-19 outbreak will stop soon in our country Jordan and the whole world, in order to reach our patients again.
    keywords: covid-19; patients
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        item: #1049 of 7819
          id: cord-260039-k9rs3dql
      author: Doerre, A.
       title: Age- and Sex-Specific Modelling of the COVID-19 Epidemic
        date: 2020-10-08
       words: 5864
      flesch: 46
     summary: Here a more substantial question arises, namely whether COVID-19 infection rates are indeed gender-specific. Both biological sex and social gender appear to affect COVID-19 infection rates and their outcomes; this needs to be acknowledged in health policy decisions and medical treatment.
    keywords: age; ages; contact; covid-19; infections; men; model; preprint; rates; sex
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        item: #1050 of 7819
          id: cord-260150-ynoevzrg
      author: Caproni, Stefano
       title: Letter to the editor: “COVID-19 does not reduce stroke-related emergencies”
        date: 2020-07-17
       words: 882
      flesch: 33
     summary: Whatever the explanation for these discrepant findings in Italy, we would like to stress the need for the establishment of stroke networks and care systems able to deliver highquality emergency stroke care at any given time, including times of crisis, particularly when and where the number of comprehensive stroke centers needs to be reduced for any reason. COVID-19 in Europe: the Italian lesson Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus infected pneumonia in Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU) On being a neurologist in Italy at the time of the COVID-19 outbreak Challenges and potential solutions of stroke care during the Coronavirus Disease 2019 (COVID-19) Outbreak Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
    keywords: covid-19; number; stroke
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        item: #1051 of 7819
          id: cord-260162-5037khjy
      author: Gupta, Nivedita
       title: Severe acute respiratory illness surveillance for coronavirus disease 2019, India, 2020
        date: 2020-04-28
       words: 1286
      flesch: 53
     summary: The median age of COVID-19 positive SARI patients was 54 yr (interquartile range: 44-63), and 85 (83.3%) were males; 83 (81.4%) of the affected patients were more than 40 yr of age. COVID-19 positive SARI patients were detected from eight districts in Maharashtra, six in West Bengal and five each in Tamil Nadu and Delhi (Table III) .
    keywords: covid-19; patients; sari
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        item: #1052 of 7819
          id: cord-260179-g9umdcn2
      author: He, Zonglin
       title: Meteorological factors and domestic new cases of coronavirus disease (COVID-19) in nine Asian cities: A time-series analysis
        date: 2020-04-18
       words: 4641
      flesch: 36
     summary: METHOD Pearson correlation and generalized additive modeling were performed to assess the relationships between daily new COVID-19 cases and meteorological factors (daily average temperature and relative humidity) with the most updated data currently available. Generalized additive models (GAMs) with a Poisson family and logarithm link function were used to estimate the associations of daily COVID-19 new cases with average temperature and relative humidity.
    keywords: cases; covid-19; daily; humidity; lag; model; relative; temperature
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        item: #1053 of 7819
          id: cord-260180-kojb8efv
      author: Elsoukkary, Sarah S.
       title: Autopsy Findings in 32 Patients with COVID-19: A Single-Institution Experience
        date: 2020-09-17
       words: 4616
      flesch: 47
     summary: A first step in understanding SARS pathogenesis COVID-19 Autopsies Pulmonary Arterial Thrombosis in COVID-19 With Fatal Outcome : Results From a Prospective, Single-Center Pulmonary Pathology of Early-Phase Novel Coronavirus (COVID-19) Pneumonia in Two Patients With Lung Cancer Dying with SARS-CoV-2 infection-an autopsy study of the first consecutive Postmortem swabs in the Sars-CoV-2 Pandemic: report on 12 complete clinical autopsy cases Ultrastructural Evidence for Direct Renal Infection with SARS-CoV-2 SARS-CoV-2 infection in conjunctival tissue -Authors' reply In situ detection of SARS-CoV-2 in lungs and airways of patients with COVID-19 Postmortem Examination of Patients With COVID-19 Molecular Detection of SARS-CoV-2 Infection in FFPE Samples and Histopathologic Findings in Fatal SARS-CoV-2 Cases SARS-CoV-2-related deaths in routine forensic autopsy practice: histopathological patterns Postmortem examination of COVID-19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: A Prospective Cohort Study Endorsed by the ISTH, NATF, ESVM, and the IUA, Supported by the ESC Working Group on Pulmonary Circulation and Right Ventricular Function. We report the clinicopathologic findings from 32 autopsy studies conducted on patients who died of COVID-19 including routine gross and microscopic examination with applicable special and immunohistochemical staining techniques.
    keywords: acute; cases; cells; cov-2; covid-19; disease; injury; patients; sars
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        item: #1054 of 7819
          id: cord-260210-u4uosc5v
      author: McKenna, Hugh
       title: Covid-19: Ethical issues for nurses
        date: 2020-10-01
       words: 1999
      flesch: 59
     summary: In effect, this means that existing intensive care unit patients may be re-assessed on their likelihood of benefiting from further treatment to make way for other patients, who would be more likely to benefit. More recently, a New York doctor took her own life after her experiences of dealing with COVID-19 patients in the emergency room ( Watkins et al., 2020 ) .
    keywords: care; covid-19; nurses; patients
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        item: #1055 of 7819
          id: cord-260214-2axc1wn3
      author: Batista, Berlinda
       title: Minimizing disease spread on a quarantined cruise ship: A model of COVID-19 with asymptomatic infections()
        date: 2020-08-07
       words: 2584
      flesch: 46
     summary: Tokyo: Ministry of Health Public health responses 627 to COVID-19 outbreaks on cruise ships -worldwide Infections in confined spaces: cruise ships, military barracks, 630 and college dormitories Common infections in nursing homes: a review 633 of current issues and challenges Respiratory infections and 636 gastrointestinal illness on a cruise ship: A three-year prospective study Norovirus transmission on cruise ship, Emerging infectious dis-642 eases Contact infection 644 of infectious disease onboard a cruise ship Influenza outbreak in a vaccinated uss ardent SARS 650 outbreaks in Ontario, Hong Kong and Singapore: the role of diagnosis 651 and isolation as a control mechanism ical Models of Isolation and Quarantine Gutier-657 rez, Investigating the impact of asymptomatic carriers on COVID-658 19 transmission How some cities flattened 661 the curve during the 1918 flu pandemic World Health Organization, Infection prevention and control guidance 665 for long-term care facilities in the context of COVID-19: interim guid-666 How an island oasis became the navy's coronavirus 670 epicenter Coronavirus contaminated cruise ships mirror the global 673 crisis COVID-19 outbreak on 677 the diamond princess cruise ship: estimating the epidemic potential 678 and effectiveness of public health countermeasures Estimating the 681 asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases 682 on board the diamond princess cruise ship The clinical charac-688 teristics of COVID-19: a retrospective analysis of 104 patients 689 from the outbreak on board the Diamond Princess cruise ship 690 in Japan Covid-19 pandemic planning scenarios, Tech. 14 Disease outbreaks in closed environments like cruise ships, nursing homes, 15 military barracks, and college dormitories (see for example [4] , [5] , a bigger concern is to stop the spread between 22 people than to find the source.
    keywords: crew; disease; passengers; quarantine; ship
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        item: #1056 of 7819
          id: cord-260218-add4i1c9
      author: Bosch‐Amate, X
       title: Retiform purpura as a dermatological sign of covid‐19 coagulopathy
        date: 2020-06-03
       words: 449
      flesch: 34
     summary: Recalcati(1) asserted that 20.4% of infected patients developed cutaneous manifestations and Galván‐Casas et al(2) have recently proposed 5 clinical patterns (pseudo‐chilblain, vesicular, urticarial, maculopapular and livedo/necrosis). From now on, we will have to include COVID-19 infection in the differential diagnosis of retiform purpura.
    keywords: covid-19; patients
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        item: #1057 of 7819
          id: cord-260232-98gtlad6
      author: Chenna, Avantika
       title: Acute Kidney Injury in a Case Series of Patients with Confirmed COVID-19 (Coronavirus Disease 2019): Role of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Blockade
        date: 2020-06-29
       words: 4313
      flesch: 48
     summary: e patients who tend to have severe disease or need intensive care unit (ICU) admission have multiorgan involvement. e patient was found to be hypoxic in the emergency room, requiring oxygen via a nasal cannula.
    keywords: ace2; angiotensin; covid-19; daily; e patient; enzyme; mouth; patient
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        item: #1058 of 7819
          id: cord-260248-yp8x5zwi
      author: Ngonghala, Calistus N
       title: Mathematical assessment of the impact of non-pharmaceutical interventions on curtailing the 2019 novel Coronavirus
        date: 2020-04-18
       words: 11144
      flesch: 47
     summary: The worst-case scenario projections for cumulative mortality (based on baseline levels of interventions) are 105, 100 for New York state and 164, 000 for the entire US by the end of the pandemic. The use of efficacious face-masks (such as surgical masks, with estimated efficacy ≥ 70%) in public could lead to the elimination of the pandemic if at least 70% of the residents of New York state use such masks in public consistently (nationwide, a compliance of at least 80% will be required using such masks).
    keywords: cases; covid-19; distancing; face; individuals; masks; model; new; pandemic; quarantine; state; york
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        item: #1059 of 7819
          id: cord-260249-dkslt9ir
      author: Vallejo, Benjamin M.
       title: Policy responses and government science advice for the COVID 19 pandemic in the Philippines: January to April 2020
        date: 2020-06-18
       words: 6142
      flesch: 48
     summary: key: cord-260249-dkslt9ir authors: Vallejo, Benjamin M.; Ong, Rodrigo Angelo C. title: Policy responses and government science advice for the COVID 19 pandemic in the Philippines: January to April 2020 date: 2020-06-18 journal: nan DOI: 10.1016/j.pdisas.2020.100115 sha: doc_id: 260249 cord_uid: dkslt9ir ABSTRACT In this paper we examine two policy questions about the COVID 19 pandemic in the Philippines. To the latter we will add the effective structures for government science advice which underpins all policy options.
    keywords: advice; covid; covid-19; crisis; data; government; health; pandemic; philippines; policy; public; sage; science; science advice
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        item: #1060 of 7819
          id: cord-260257-phmd0u6d
      author: Siegler, Aaron J
       title: Willingness to seek laboratory testing for SARS-CoV-2 with home, drive-through, and clinic-based specimen collection locations
        date: 2020-06-30
       words: 3715
      flesch: 44
     summary: Differences in mean willingness scores across testing modalities were all significant (p<.001), with very small effect size for home saliva testing compared to home throat swab testing (d=0.12), medium effect size for home saliva testing compared to drive-through testing (d=0.55), and large effect size for home saliva testing compared to clinic-based testing (d=0.81). There was a hierarchy of willingness to test for SARS-CoV-2 that was decreased as the required degree of contact with healthcare systems increased: home testing was most preferred, followed by drive-through testing, and then by laboratory or clinicbased testing.
    keywords: collection; covid-19; drive; home; sars; specimen; testing; willingness
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        item: #1061 of 7819
          id: cord-260264-8fzlllde
      author: Kahan, Barry D.
       title: COVID-19 Minisymposium: Toward a Strategic Roadmap
        date: 2020-10-06
       words: 1859
      flesch: 37
     summary: Early report on published outcomes in kidney transplant recipients compared to non-transplant patients infected with COVID-19 COVID-19 viremia, serologies and clinical course in a case series of transplant recipients Clinical presentation, treatment and mortality rate in liver transplant recipients with COVID-19: a systematic review & quantitative analysis Deceased donor liver transplantation in India in the COVID-19 era: current scenario and future perspectives A kidney transplant recipient with COVID-19: utility of a prognostication score A case report: minimal change disease with nephrotic syndrome associated with COVID-19 after APOL1 risk variant in kidney transplantation COVID-19 in immunocompromised organ transplant recipients: a case report and review of the literature Recovery of moderate COVID-19 in a liver transplant recipient on continued immunosuppression: a case report Bilateral acute cardioembolic limb ischemia after COVID-19 pneumonia in a lung transplant recipient: a case report Successful treatment of severe COVID-19 pneumonia with clazakizumab in a heart transplant recipient: case report The impact of COVID-19 on solid organ donation: the North Italy Transplantation program (NITp) experience Dealing with liver transplantation in the SARS-CoV-2 pandemic: normothermic machine perfusion enables for donor, organ and recipient assessment-a case report Rapid modification of workflows and fellow staffing at a single transplant center to address the COVID-19 crisis Identifying a kidney transplant recipient COVID phenotype to aid test utilization in the setting of limited testing availability-does one exist? Follow-up and management of kidney transplant recipients during the COVID-19 lockdown: the experience of an Italian transplant center, including two cases of COVID-19 pneumonia Challenges for liver transplantation during recovery from the COVID-19 pandemic: insights and recommendations Awareness and impact of non-pharmaceutical interventions during COVID-19 pandemic in renal transplant recipients Use of donor-derived cellfree DNA for assessment of allograft injury in kidney transplant recipients during the time of the COVID-19 pandemic Psychological responses to the COVID-19 pandemic in renal transplant recipients Transplant patients' isolation and social distancing due to COVID-19: analysis of the resilient capacities of the transplant in the management of the coronavirus emergency Telemedicine in the care of kidney transplant recipients with COVID-19: case reports Solid organ transplantation in the coronavirus disease 2019 (COVID-19) era: the great bet in the North Italy Transplant program (NITp) area Effects of COVID-19 on solid organ transplantation Spectrum of COVID-19 outcomes in kidney transplant recipients-a single center experience Oligosymptomatic kidney transplant patients with COVID-19: do they pose a risk to other recipients?
    keywords: covid-19; kidney; recipients; transplant; transplantation
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        item: #1062 of 7819
          id: cord-260274-c3586tp6
      author: Somers, Emily C
       title: Tocilizumab for treatment of mechanically ventilated patients with COVID-19
        date: 2020-07-11
       words: 3655
      flesch: 30
     summary: Untreated patients who died prior to the opportunity to receive tocilizumab treatment per institutional criteria (within 48 hours of intubation) were excluded to minimize immortal time bias. To address non-randomized treatment allocation, we calculated propensity scores by multivariable logistic regression with tocilizumab treatment as the binary outcome and potential confounding factors associated with both outcome and treatment assignment.
    keywords: covid-19; il-6; patients; pneumonia; respiratory; study; superinfection; tocilizumab; treatment; ventilation
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        item: #1063 of 7819
          id: cord-260279-igra1q3j
      author: Slanetz, Priscilla J.
       title: Coronavirus Disease 2019 (COVID-19) and Radiology Education—Strategies for Survival
        date: 2020-04-23
       words: 1459
      flesch: 42
     summary: Special communication to diagnostic radiology residents, interventional radiology residents, subspecialty radiology fellows, and program directors Ujas Parikh, MD, is from the Department of Radiology In addition, senior residents with an interest in radiology education can help develop curricular materials in their area of interest when they are on a remote study rotation.
    keywords: covid-19; learning; radiology; residents
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        item: #1064 of 7819
          id: cord-260322-b2493coe
      author: Mehring, William M.
       title: Initial Experience with a COVID-19 Web-Based Patient Self-assessment Tool
        date: 2020-06-15
       words: 689
      flesch: 42
     summary: Nevertheless, the widespread use of our tool highlights the willingness of the public to engage with digital health tools and self-assessment in this time of public health crisis. Automated assessment tools-such as digital self-assessment applications-offer a potential strategy for providing guidance to patients without requiring direct attention from healthcare professionals.
    keywords: covid-19; self; tool
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        item: #1065 of 7819
          id: cord-260332-tnz6k2z1
      author: Tran, Tu Anh
       title: CT scan does not make a diagnosis of Covid-19: a cautionary case report()
        date: 2020-09-02
       words: 340
      flesch: 53
     summary: This case must draw attention on the risk of false COVID-19 diagnosis when relying overly on CT scan imaging. RT-PCR assays of nasopharyngeal samples at admittance and 24 hours later, were negative for SARS-CoV-2. Basing Covid-19 diagnosis strictly on clinical signs and imaging may lead to false positive diagnosis, resulting in inappropriate medical care and errors in contact tracing.
    keywords: case; report
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        item: #1066 of 7819
          id: cord-260349-dm39opvg
      author: Frank, P.
       title: Trajectories of depressive symptoms among vulnerable groups in the UK during the COVID-19 pandemic
        date: 2020-06-11
       words: 4298
      flesch: 43
     summary: After adjusting for covariates, experiences of physical/psychological abuse (OR 13.16, 95% CI 12.95-13.37), pre-existing mental health conditions (OR 13.00 95% CI 12.87-13.109), pre-existing physical health conditions (OR 3.41, 95% CI 3.29-3.54), low social support (OR 12.72, 95% CI 12.57-12.86), and low SEP (OR 5.22, 95% CI 5.08-5.36) were significantly associated with the severe DST. Third, the study was promoted via partnerships with third sector organisations to vulnerable groups, including adults with pre-existing mental health conditions, older adults, carers, and people experiencing domestic violence or abuse.
    keywords: covid-19; health; license; medrxiv; pandemic; preprint; symptoms
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        item: #1067 of 7819
          id: cord-260365-neili1bd
      author: Silverstein, Jenna S.
       title: Acute Respiratory Decompensation Requiring Intubation in Pregnant Women with SARS-CoV-2 (COVID-19)
        date: 2020-06-04
       words: 2216
      flesch: 44
     summary: 3 Other series from China have reported similar rates with no apparent increased risk of severe or critical illness for pregnant patients when compared with nonpregnant patients. The risks and benefits of delivery in pregnant patients with critical respiratory illness from COVID-19 infections are not yet known, but prior experience with maternal acute respiratory distress syndrome (ARDS) and viral 2009/H1N1 influenza requiring mechanical ventilation in pregnancy reveals increased risk of fetal HR abnormalities, as well as fetal and neonatal mortality.
    keywords: covid-19; day; delivery; patients
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        item: #1068 of 7819
          id: cord-260374-06j1jlc6
      author: Gao, Feng
       title: COVID‐19 and liver transplantation: Lessons learned from three reported cases
        date: 2020-06-02
       words: 594
      flesch: 39
     summary: We reviewed three reported cases with detailed treatment information from China to better understand the features and associated therapeutic strategies used in transplant recipients with COVID-19.2-4. To the Editor, During the COVID-19 pandemic, transplant recipients have been recognized as more susceptible to infection, to have greater severity of disease, and prolonged shedding of this highly transmissible virus. We reviewed three reported cases with detailed treatment information from China to better understand the features and associated therapeutic strategies used in transplant recipients with COVID-19.
    keywords: covid-19; transplant
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        item: #1069 of 7819
          id: cord-260441-3t7ppofw
      author: Morvan, J.-B.
       title: Trachéotomie percutanée pour afflux saturant de patients COVID-19: expérience des ORL militaires déployés à Mulhouse
        date: 2020-06-25
       words: 3717
      flesch: 49
     summary: Le MAR réalisait systématiquement une échographie cervicale afin de confirmer le niveau de la trachée cervicale et sa profondeur, de vérifier l'absence d'isthme thyroïdien épais et de vascularisation à risque sur la ligne médiane. avec une difficulté technique notée dans un cas (obstruction de la sonde d'intubation par des sécrétions épaisses imposant un changement de sonde d'intubation sur guide préalable à la TPD) et des complications per-procédure mineures dans deux cas : désaturation d'installation rapide jusqu'à 40 % de SpO² sans arrêt cardiaque et de durée inférieure à la minute, imposant le retrait du fibroscope avec des pauses répétées durant la procédure pour optimiser l'oxygénation dans le premier cas, localisation de la trachée difficile avec ponctions itératives dans le second cas.
    keywords: cas; covid-19; d'une; dans; des; les; par; patients; pour; procédure; risque; technique; trachéotomie; une; était
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        item: #1070 of 7819
          id: cord-260456-kjmab3og
      author: Hegde, Shruti
       title: Massive Pulmonary Embolism Complicating Coronavirus Disease 2019 (COVID-19) Pneumonia: A Case Report
        date: 2020-10-28
       words: 1861
      flesch: 45
     summary: A pneumonia outbreak associated with a new coronavirus of probable bat origin Coronavirus COVID-19 Global Multiple enzyme release, inflammation storm and hypercoagulability Are&nbsp;Prominent Indicators&nbsp;For disease Progression&nbsp;In COVID-19: a multi-centered, Correlation&nbsp;Study with CT imaging score Regional right ventricular dysfunction detected by echocardiography in acute pulmonary embolism Clinical characteristics of coronavirus disease 2019 in China Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Empirical systemic anticoagulation is associated with decreased venous thromboembolism in critically ill influenza A H1N1 acute respiratory distress syndrome patients Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Clinical and coagulation characteristics of 7 patients with critical COVID-2019 pneumonia and acro-ischemia Findings of acute pulmonary embolism in COVID-19 patients (3) Critical care bedside echocardiography along with other clinical indicators helps in timely diagnosis and thus treatment of APE in patients with COVID-19 pneumonia, which is lifesaving.
    keywords: ape; case; clinical; covid-19; patients; pneumonia
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        item: #1071 of 7819
          id: cord-260525-bohv78hi
      author: Mei, Yang
       title: Risk stratification of hospitalized COVID-19 patients through comparative studies of laboratory results with influenza
        date: 2020-07-31
       words: 4178
      flesch: 45
     summary: In this study, we compared the laboratory manifestations of COVID-19 patients admitted to Northwestern Medicine Health System and compared these findings to a cohort of influenza patients. However, COVID-19 patients dropped more rapidly and plummeted to the same levels as influenza patients in the later stages of disease course.
    keywords: blood; clusters; covid-19; data; influenza; laboratory; parameters; patients
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        item: #1072 of 7819
          id: cord-260559-n8i52e8q
      author: Peiris, Malik
       title: What can we expect from first-generation COVID-19 vaccines?
        date: 2020-09-21
       words: 1356
      flesch: 33
     summary: key: cord-260559-n8i52e8q authors: Peiris, Malik; Leung, Gabriel M title: What can we expect from first-generation COVID-19 vaccines? date: 2020-09-21 journal: Lancet DOI: 10.1016/s0140-6736(20)31976-0 sha: doc_id: 260559 cord_uid: n8i52e8q nan A first generation of COVID-19 vaccines is expected to gain approval as soon as the end of 2020 or early 2021. These observations suggest that we cannot assume COVID-19 vaccines, even if shown to be effective in reducing severity of disease, will reduce virus transmission to a comparable degree.
    keywords: covid-19; infection; sars; vaccines
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        item: #1073 of 7819
          id: cord-260585-ovmko655
      author: Sherman, Allen C.
       title: Mental Health Outcomes Associated with the COVID-19 Pandemic: Prevalence and Risk Factors in a Southern US State
        date: 2020-09-24
       words: 4935
      flesch: 33
     summary: In bivariate analyses, participants who experienced greater disruption in daily life due to the pandemic (all p's ≤.0002), and those who believed or suspected that they had been infected with the virus (all p's ≤.0005), were significantly more likely to screen positive on all three outcomes ( This study offers an initial evaluation of mental health outcomes in response to the COVID-19 pandemic among community residents in Arkansas. This study is among the first to examine mental health outcomes among community residents in Arkansas, and one of the few investigations to use validated screening tools to evaluate these outcomes in the US.
    keywords: anxiety; covid-19; depression; et al; health; individuals; outcomes; pandemic; symptoms
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        item: #1074 of 7819
          id: cord-260586-ry0roidc
      author: Felsenstein, Daniel
       title: Introduction to the Special Issue: Cascading Effects in Disaster Risk Management Cascades - Mapping the Multi-Disciplinary Landscape in a Post-Pandemic World
        date: 2020-09-10
       words: 3429
      flesch: 40
     summary: The contributions to this special issue originate from a scientific workshop on the topic of Cascading Disasters: Theory, Methods, and Empirics held at the Technion -Israel Institute of Technology, Haifa, in November 2018. Taking a people-centric lens of how social processes intensify disasters, the model illustrates how cascading disasters almost predictably give rise to socially inequitable disruptions and consequences.
    keywords: cascades; cascading; covid-19; disaster; effects; management; networks; pandemic; risk
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        item: #1075 of 7819
          id: cord-260629-ml1qjipn
      author: Kopelovich, Sarah L.
       title: Community Mental Health Care Delivery During the COVID-19 Pandemic: Practical Strategies for Improving Care for People with Serious Mental Illness
        date: 2020-06-19
       words: 7380
      flesch: 31
     summary: The COVID-19 pandemic has presented a formidable challenge to care continuity for community mental health clients with serious mental illness and for providers who have had to quickly pivot the modes of delivering critical services. For instance, the Office for Civil Rights (OCR) has announced that it would waive penalties embedded in the Health Insurance Portability and Accountability Act (HIPAA) against health care providers who serve their clients using everyday communications technologies, (Department of Health and Human Services 2020) although we are sensitive to the dialectic between reducing barriers to care and protecting patient rights (Hall and McGraw 2014) .
    keywords: care; clients; covid-19; health; interventions; need; pandemic; person; providers; psychiatric; risk; services; support; telehealth; treatment; use
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        item: #1076 of 7819
          id: cord-260642-qzc3etlx
      author: Liao, Zhongxing
       title: Optimizing lung cancer radiation treatment worldwide in COVID-19 outbreak
        date: 2020-05-26
       words: 3706
      flesch: 42
     summary: The coronavirus is more dangerous to the elderly and those with certain pre-existing medical conditions which is precisely the profile of lung cancer patients. The decision-making paths strongly depend on locally available resources, and a tailored approach should be used to attend lung cancer patients during this pandemic.
    keywords: cancer; cell; covid-19; lung; patients; radiation; stage
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        item: #1077 of 7819
          id: cord-260674-a0ejus6m
      author: Chopra, Sakshi
       title: Impact of COVID-19 on lifestyle-related behaviours- a cross-sectional audit of responses from nine hundred and ninety-five participants from India
        date: 2020-10-06
       words: 4291
      flesch: 41
     summary: The questionnaire has three sections assessing socio-demographic details, changes in lifestyle related behaviour and COVID specific reasons for the changes in these behaviors. The comparison of mean scores of lifestyle related behaviours before and during COVID-19 is shown in Table 3 .
    keywords: activity; changes; covid-19; eating; food; lifestyle; participants; study
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        item: #1078 of 7819
          id: cord-260693-8mfuwx8l
      author: Seelig, Frederik
       title: The COVID-19 pandemic should not derail global vector control efforts
        date: 2020-08-31
       words: 1130
      flesch: 39
     summary: [7, 8] , with respect to inter-and intrasectoral collaboration, engagement and mobilisation of communities, and scaling up of vector control if required, according to the implementation plan of vector control activities, while adapting activities as necessary to prevent further spread of COVID-19, in particular vector surveillance, which may need to be scaled down [9, 10] . In view of these combined challenges, we reiterate our solidarity with the global partners who are dealing with the COVID-19 pandemic, while strongly urging them to consider these recommendations for the control of VBDs: • Continue the implementation of the WHO's global vector control response 2017-2030 (GVCR) strategy and regional policies for vector control
    keywords: control; covid-19; health; vector
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        item: #1079 of 7819
          id: cord-260697-oepk0b1d
      author: Huang, J.
       title: COVID-19 Recurrent Varies with Different Combinatorial Medical Treatments Determined by Machine Learning Approaches
        date: 2020-08-01
       words: 5736
      flesch: 46
     summary: In supporting the notion of anti-cytokine storm may be beneficial to COVID-19 patients, the administration of anti-inflammation drug, Methylprednisolone, slowed down the disease progress and reduced death rate (19) .Findings from a preliminary, uncontrolled study revealed that IFN alfacon-1 plus corticosteroids was associated with reduced disease-associated impaired oxygen saturation, more rapid resolution of radiographic lung abnormalities in SARS patients, demonstrating antiviral activity against MERS (18, 19) . Cough (16%) and sputum (11%) were the main symptoms of recurring patients at follow-up.
    keywords: age; covid-19; drug; lopinavir; medrxiv; patients; preprint; rate; sars; treatment
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        item: #1080 of 7819
          id: cord-260702-1ljyk8uw
      author: El Hamichi, Sophia
       title: Pandemics, climate change, and the eye
        date: 2020-09-30
       words: 2587
      flesch: 44
     summary: Global Warming of 1.5C. An IPCC Special report on the impacts of global warming of 1.5C above pre-industrial levels and related global greenhouse gas emission pathways, in the context of strengthening the global response to the threat of climate change, sustainable development, and efforts to eradicate poverty key: cord-260702-1ljyk8uw authors: El Hamichi, Sophia; Gold, Aaron; Murray, Timothy G.; Graversen, Veronica Kon title: Pandemics, climate change, and the eye date: 2020-09-30 journal: Graefes Arch Clin Exp Ophthalmol DOI: 10.1007/s00417-020-04947-7 sha: doc_id: 260702 cord_uid: 1ljyk8uw nan Global climate change is primarily a sequel of human's impact on the planet.
    keywords: air; change; climate; covid-19; eye; global; pandemic; waste; world
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        item: #1081 of 7819
          id: cord-260723-y4ow6n8r
      author: Dorey-Stein, Zachariah L.
       title: Case Series: Failure of imaging & biochemical markers to capture disease progression in COVID-19
        date: 2020-09-19
       words: 1607
      flesch: 41
     summary: We propose a multi-disciplinary discharge criterion to establish a safer discharge process including trending inflammatory markers, daily imaging and pursuing follow up CT chest, particularly in individuals with significant morbidities and health disparities. CT chest showed diffuse peripheral predominant bibasilar and right upper lobe ground glass opacities.
    keywords: chest; day; discharge; markers
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        item: #1082 of 7819
          id: cord-260730-w9yv4jd7
      author: Neff, Shawn M.
       title: Guidance concerning chiropractic practice in response to COVID-19 in the U.S.: a summary of state regulators’ web-based information
        date: 2020-07-06
       words: 4003
      flesch: 40
     summary: [5] , and such information may be customized and disseminated by chiropractic state boards to meet specific state and professional requirements. State chiropractic licensing boards play an important role in protecting the public via regulation of licensure and provision of guidance regarding standards of practice, especially during times of change or uncertainty.
    keywords: boards; chiropractic; chiropractors; covid-19; guidance; information; licensing; state
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        item: #1083 of 7819
          id: cord-260762-1kuj5dzz
      author: Elledge, Christen R.
       title: Radiation therapy for gynecologic malignancies during the COVID-19 pandemic: International expert consensus recommendations
        date: 2020-06-15
       words: 3973
      flesch: 30
     summary: Additionally, cancer patients may have an increased risk of contracting the virus or difficulty clearing the virus once infected due to their immunocompromised state. Two independent studies have reported a greater risk of severe events (ICU admission, mechanical ventilation, and death) secondary to COVID-19 in cancer patients compared to patients without cancer in China.
    keywords: cancer; consensus; covid-19; patients; radiation; recommendations; therapy; treatment
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        item: #1084 of 7819
          id: cord-260807-uyb45nye
      author: McCullough, Laurence B.
       title: Teaching Professional Formation in Response to the COVID-19 Pandemic
        date: 2020-04-22
       words: 2774
      flesch: 34
     summary: Professional ethics in medicine provides powerful conceptual tools that can be used as an ethical framework to guide medical educators to teach learners, who will bear leadership responsibilities in responses to future pandemics, professional formation. Professional ethics in medicine provides powerful conceptual tools that can be used as an ethical framework to guide medical educators to teach learners, who will bear leadership responsibilities in responses to future pandemics, professional formation.
    keywords: learners; medical; risk; teaching
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        item: #1085 of 7819
          id: cord-260826-1n96pz86
      author: Shet, Anita
       title: Differential COVID-19-attributable mortality and BCG vaccine use in countries
        date: 2020-04-06
       words: 2584
      flesch: 30
     summary: Recent non-peer reviewed work reported a similar negative association between BCG use and COVID-19 mortality 19 . We surmised that since susceptibility to COVID-19 infection extends to the entire population, crude national COVID-19-specific mortality within the country-specific population would be an informative outcome indicator to study differences in mortality patterns amongst countries, in addition to a priori defined potential exposure variables including BCG vaccine use in national immunization schedules.
    keywords: bcg; countries; covid-19; disease; mortality; population; preprint
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        item: #1086 of 7819
          id: cord-260852-u0gpklj7
      author: Osman, Mohammed
       title: Impaired natural killer cell counts and cytolytic activity in patients with severe COVID-19
        date: 2020-10-19
       words: 2283
      flesch: 33
     summary: COVID-19: consider cytokine storm syndromes and immunosuppression Fatal COVID-19 infections: is NK cell dysfunction a link with autoimmune HLH? Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis Hemophagocytic lymphohistiocytosis: a diagnostic conundrum NK cell education after allogeneic transplantation: dissociation between recovery of cytokine-producing and cytotoxic functions Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome The inhibitory receptors on NK cells and CTLs are upregulated in adult and adolescent patients with secondary hemophagocytic lymphohistiocytosis Functional exhaustion of antiviral lymphocytes in COVID-19 patients A single-cell atlas of the peripheral immune response in patients with severe COVID-19 Sinai Immunology Review Project. Serum concentrations of soluble CD25 (sCD25)/soluble IL2 receptor α (sIL2-Rα) were significantly elevated and were inversely correlated with the percentage of NK cells.
    keywords: activity; cell; counts; covid-19; patients; syndrome
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        item: #1087 of 7819
          id: cord-260854-v7wgb6mr
      author: Colafrancesco, Serena
       title: COVID-19 gone bad: A new character in the spectrum of the hyperferritinemic syndrome?
        date: 2020-05-05
       words: 3342
      flesch: 27
     summary: A significant amount of COVID-19 patients is currently experiencing severe interstitial pneumonia possibly ending up with acute respiratory distress syndrome (ARDS) and systemic inflammatory response syndrome (SIRS). However, as noted by Mc Gonagle D and coll, the increased vascular coagulation occurring in COVID-19 patients is more close to a lung centric pulmonary intravascular coagulopathy (PIC) rather than a classical DIC
    keywords: coronavirus; covid-19; disease; ferritin; inflammation; inflammatory; patients; sars; syndrome
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        item: #1088 of 7819
          id: cord-260857-oxxle915
      author: Samuel, Sharmeen
       title: INCIDENCE OF ARRHYTHMIAS AND ELECTROCARDIOGRAPHIC ABNORMALITIES IN SYMPTOMATIC PEDIATRIC PATIENTS WITH PCR POSITIVE SARS-CoV-2 INFECTION INCLUDING DRUG INDUCED CHANGES IN THE CORRECTED QT INTERVAL (QTc).
        date: 2020-07-01
       words: 4188
      flesch: 40
     summary: There are several main findings of this paper including the following:1) significant arrhythmias in pediatric patients with COVID-19 infection are infrequent but occur at incidence higher than expected in a general pediatric population, 2) comorbidities are not more common in COVID-19 patients with arrhythmias. The Lancet Cardiac involvement in COVID-19 patients: Risk factors, predictors, and complications: A review Cardiac Arrhythmias in COVID-19 Infection Guidance for Cardiac Electrophysiology During the Coronavirus (COVID-19) Pandemic from the Heart Rhythm Society COVID-19 Task Force; Electrophysiology Section of the American College of Cardiology; and the Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology Drug-induced ventricular tachycardia Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society.
    keywords: arrhythmias; covid-19; hcq; patients; qtc; study; treatment
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        item: #1089 of 7819
          id: cord-260866-bzdd4f5h
      author: Barceló, Damià
       title: Wastewater-Based Epidemiology to Monitor COVID-19 Outbreak: Present and Future Diagnostic Methods to be in Your Radar
        date: 2020-09-14
       words: 4680
      flesch: 44
     summary: Shortly afterwards, the National Medical Products Administration (NMPA) announced nucleic acid testing as the gold standard for virus detection. Most importantly is to encourage the scientists involved in virus detection in WBE to think outside the PCR box by considering other complementary ways to detect COVID-19 outbreak in wastewaters .
    keywords: biomarkers; biosensors; cov-2; covid-19; detection; methods; pcr; sars; virus; viruses; wastewater; wbe
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        item: #1090 of 7819
          id: cord-260871-dtn5t8ka
      author: Silva, Marcus Tulius T.
       title: SARS-CoV-2: Should We Be Concerned about the Nervous System?
        date: 2020-07-17
       words: 4122
      flesch: 36
     summary: [39] Typically, SARS patients exhibited a triphasic pattern of disease, initially presenting with fever, a nonproductive cough, sore throat, and myalgia. A novel syndrome Self-reported olfactory and taste disorders in SARS-CoV-2 patients: a cross-sectional study Entry of coronavirus into primate CNS following peripheral infection SARS-associated coronavirus Coronavirus pathogenesis Renin-angiotensin-aldosterone system inhibitors in patients with COVID-19 Angiotensin-converting enzyme 2 in the brain: properties and future directions Epidemiological and clinical features of human coronavirus infections among different subsets of patients Epidemiology and clinical presentations of the four human coronaviruses 229E, HKU1, NL63, and OC43 detected over 3 years using a novel multiplex real-time PCR method Detection of the human coronavirus 229E, HKU1, NL63, and OC43 between 2010 and 2013 in Yamagata Two coronaviruses isolated from central nervous system tissue of two multiple sclerosis patients Murine hepatitis virus-a model for virus-induced CNS demyelination Human coronaviruses: viral and cellular factors involved in neuroinvasiveness and neuropathogenesis Genomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human Phylogeny of the SARS coronavirus The genome sequence of the SARSassociated coronavirus Characterization of a novel coronavirus associated with severe acute respiratory syndrome The severe acute respiratory syndrome Severe acute respiratory syndrome and critical care medicine: the Toronto experience Olfactory neuropathy in severe acute respiratory syndrome: report of a case Detection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndrome Pathological findings of COVID-19 associated with acute respiratory distress syndrome Multiple organ infection and the pathogenesis of SARS Persistence of physical symptoms in and abnormal laboratory findings for survivors of severe acute respiratory syndrome Hypocortisolism in survivors of severe acute respiratory syndrome (SARS) Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice Coronavirus infection of rat dorsal root ganglia: ultrastructural characterization of viral replication, transfer, and the early response of satellite cells Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding A pneumonia outbreak associated with a new coronavirus of probable bat origin Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neurotropic mechanisms The vagus nerve is one route of transneural invasion for intranasally inoculated influenza A virus in mice CNS innervation of vagal preganglionic neurons controlling peripheral airways: a transneuronal labeling study using pseudorabies virus Middle east respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4 Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Detection of severe acute respiratory syndrome coronavirus in the brain: potential role of the chemokine mig in pathogenesis A first case of meningitis/encephalitis associated with SARS-coronavirus-2 COVID-19: consider cytokine storm syndromes and immunosuppression Guillain-barré syndrome associated with SARS-CoV-2 Miller fisher syndrome and polyneuritis cranialis in COVID-19 Pearls and oysters: facial nerve palsy as a neurological manifestation of COVID-19 infection Neurologic features in severe SARS-CoV-2 infection Large-vessel stroke as a presenting feature of COVID-19 in the young COVID-19 and its implications for thrombosis and anticoagulation D-dimer levels on admission to predict in-hospital mortality in patients with COVID-19 Central nervous system involvement by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the central nervous system Neurologic alterations due to respiratory virus infections
    keywords: acute; coronavirus; cov; cov-2; covid-19; human; infection; patients; sars; syndrome
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        item: #1091 of 7819
          id: cord-260874-g3k562od
      author: Pontieri-Lewis, Vicky
       title: Adapting WOC Nursing Practice to the COVID-19 Pandemic: A View From Here
        date: 2020-06-15
       words: 2030
      flesch: 52
     summary: I began to see the influx of COVID-19 patients into our hospital and noticed how ill they were upon admission and how quickly their condition deteriorated. Some of the skin damage that I am seeing presents with bruising (purpura) appearance and or reddish/purple in color (petechiae), very similar to the characteristics we commonly see with deep tissue injuries; however, some of the skin damage on COVID-19 patients may or may not present on a bony prominence or under a medical device.
    keywords: care; covid-19; nurse; patients; woc
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        item: #1092 of 7819
          id: cord-260921-9xgrthg7
      author: Ahuja, Abhimanyu S.
       title: Artificial Intelligence and COVID-19: A Multidisciplinary Approach
        date: 2020-05-27
       words: 1905
      flesch: 49
     summary: Drug discovery is not a trivial task and AI technologies like deep learning can help accelerate this process by helping predict which existing drugs, or brand-new drug-like molecules could treat COVID-19. Though the situation may appear grim, it is important to draw attention to AI technologies that can ameliorate some of the most pressing and timely problems that this pandemic has created.
    keywords: cov-2; covid-19; sars; vaccine
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        item: #1093 of 7819
          id: cord-260923-hwvtxy9g
      author: Jain, Amit
       title: Dexmedetomidine: another arrow in the quiver to fight COVID-19 disease in intensive care units
        date: 2020-10-14
       words: 622
      flesch: -12
     summary: As, dexmedetomidine can suppress mitochondrial reactive oxygen species formation and inhibit HIF-1α dependent glycolysis in preclinical settings, 23 we believe that early use of A novel role for lidocaine in COVID-19 patients? A New Virus, but a Familiar Receptor and Cytokine Release Syndrome COVID-19 and the nicotinic cholinergic system Dexmedetomidine and worsening hypoxemia in the setting of COVID-19: A case report Potential therapeutic value of dexmedetomidine in COVID-19 patients admitted to ICU Dexmedetomidine protects against high mobility group box 1-induced cellular injury by inhibiting pyroptosis Dexmedetomidine Preconditioning Protects Cardiomyocytes Against Hypoxia/Reoxygenation-Induced Necroptosis by Inhibiting HMGB1-Mediated Inflammation Effects of Dexmedetomidine Infusion on Inflammatory Responses and Injury of Lung Tidal Volume Changes during One Lung Ventilation in Thoracoscopic Surgery: A Randomized Controlled Trial Dexmedetomidine regulates inflammatory molecules contributing to ventilator-induced lung injury in dogs The dose-related effects of dexmedetomidine on renal functions and serum neutrophil gelatinase-associated lipocalin values after coronary artery bypass grafting: a randomized, triple-blind, placebo-controlled study The influence of dexmedetomidine and propofol on circulating cytokine levels in healthy subjects TH17 responses in cytokine storm of COVID-19:
    keywords: covid-19; dexmedetomidine; patients
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        item: #1094 of 7819
          id: cord-260980-tyf3fuz9
      author: Lorenzo Villalba, Noel
       title: Anosmia and Dysgeusia in the Absence of Other Respiratory Diseases: Should COVID-19 Infection Be Considered?
        date: 2020-04-03
       words: 1217
      flesch: 48
     summary: He lived with his wife and there was apparently no close contact with anybody with acute respiratory symptoms. Anosmia, hyposmia and dysgeusia in the absence of other respiratory diseases such as allergic rhinitis, acute rhinosinusitis or chronic rhinosinusitis, should alert physicians to the possibility of COVID-19 infection and prompt serious consideration of self-isolation and testing of these individuals.
    keywords: anosmia; covid-19; patients; symptoms
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        item: #1095 of 7819
          id: cord-260993-udajtsmm
      author: Youssef, Mohanad
       title: COVID‐19 and Liver Dysfunction: a systematic review and meta‐analysis of retrospective studies
        date: 2020-05-23
       words: 2059
      flesch: 45
     summary: On comparison between the two groups, severe patients were nearly three times more likely to receive steroids (OR = 3.17, 95%CI = 3.02-4.97, p <0.001) and immunoglobulins (OR = 2.75, 95%CI = 1.09-6.94, p = 0.032). A total of 20 eligible retrospective cohort studies, including 3428 positively confirmed COVID-19 patients, were enrolled in the current meta-analysis.
    keywords: coronavirus; covid-19; disease; liver; patients; studies
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        item: #1096 of 7819
          id: cord-260995-ji8aifck
      author: Mohindra, Pranshu
       title: Proposed brachytherapy recommendations (practical implementation, indications, and dose fractionation) during COVID-19 pandemic
        date: 2020-05-01
       words: 2023
      flesch: -23
     summary: Part II: High-dose-rate brachytherapy Compendium of fractionation choices for gynecologic HDR brachytherapy-an American brachytherapy society Task group report Radiobiological analysis of outcomes using external beam radiotherapy plus high doserate brachytherapy (4x7 Gy or 2x9 Gy) for cervical cancer in a multi-institution trial Endometrial cancer in an increasingly obese population: Exploring alternative options when surgery may not cut it Definitive radiation therapy for stage I-II endometrial cancer: An observational study of nonoperative management Image-guided tandem and cylinder brachytherapy as monotherapy for definitive treatment of inoperable endometrial carcinoma Consensus statement for brachytherapy for the treatment of medically inoperable endometrial cancer Long-term results of high-dose-rate brachytherapy in the primary treatment of medically inoperable stage I-II endometrial carcinoma American Brachytherapy Society consensus guidelines for interstitial brachytherapy for vaginal cancer Cervical cancer brachytherapy in Canada: A focus on interstitial brachytherapy utilization CT-based interstitial brachytherapy in advanced gynecologic malignancies: Outcomes from a single institution experience Interval between hysterectomy and start of radiation treatment is predictive of recurrence in patients with endometrial carcinoma Relationship between interval from surgery to radiotherapy and local recurrence rate in patients with endometrioid-type endometrial cancer: A retrospective mono-institutional Italian study American Brachytherapy Society consensus guidelines for adjuvant vaginal cuff brachytherapy after hysterectomy Vaginal brachytherapy versus pelvic external beam radiotherapy for patients with endometrial cancer of high-intermediate risk (PORTEC-2): An open-label, non-inferiority, randomised trial Low-dose 3-fraction adjuvant vaginal brachytherapy for early-stage endometrial cancer Long-term outcomes using adjuvant pelvic intensity modulated radiation therapy (IMRT) for endometrial carcinoma Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): Patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial Mature clinical outcomes after vaginal vault high-dose-rate brachytherapy boost for endometrial cancers: Changing our provincial guidelines Prostate high dose-rate brachytherapy as monotherapy for low and intermediate risk prostate cancer: Efficacy results from a randomized phase II clinical trial of one fraction of 19 Gy or two fractions of 13 Results of 15 Gy HDR-BT boost plus EBRT in intermediate-risk prostate cancer: Analysis of over 500 patients Long-term toxicity and health-related quality of life after single-fraction high dose rate brachytherapy boost and hypofractionated external beam radiotherapy for intermediate-risk prostate cancer A Phase II study of salvage high-dose-rate brachytherapy for the treatment of locally recurrent prostate cancer after definitive external beam radiotherapy Salvage HDR brachytherapy for recurrent prostate cancer after previous definitive radiation therapy: 5-year outcomes Timing of radiotherapy and outcome in patients receiving adjuvant endocrine therapy Intervals longer than 20 weeks from breast-conserving surgery to radiation therapy are associated with inferior outcome for women with early-stage breast cancer who are not receiving chemotherapy Delay in radiotherapy is associated with an increased risk of disease recurrence in women with ductal carcinoma in situ The American Brachytherapy Society consensus statement for accelerated partial-breast irradiation Three-fraction intracavitary accelerated partial breast brachytherapy: Early provider and patient-reported outcomes of a novel regimen Three-fraction accelerated partial breast irradiation (APBI) delivered with brachytherapy applicators is feasible and safe: First results from the TRIUMPH-T trial Six-year results from a phase I/II trial for hypofractionated accelerated partial breast irradiation using a 2-day dose schedule Recommendations of the Spanish brachytherapy group (GEB) of Spanish Society of Radiation Oncology (SEOR) and the Spanish Society of Medical Physics (SEFM) for high-dose rate (HDR) non melanoma skin cancer brachytherapy GEC-ESTRO ACROP recommendations in skin brachytherapy Aspects of dosimetry and clinical practice of skin brachytherapy: Pranshu Mohindra, MD Emergency departments and the COVID-19 pandemic: Making the most of limited resources Fair allocation of scarce medical resources in the time of covid-19 Challenges for NHS hospitals during covid-19 epidemic Projecting hospital utilization during the COVID-19 outbreaks in the United States A practical approach to the management of cancer patients during the novel coronavirus disease 2019 (COVID-19) pandemic: An international collaborative group Clinical characteristics of COVID-19-infected cancer patients: A retrospective case study in three hospitals within Wuhan, China Cancer care delivery challenges amidst coronavirus disease e 19 (COVID-19) outbreak: Specific precautions for cancer patients and cancer care providers to prevent spread Cancer patients in SARS-CoV-2 infection: A nationwide analysis in China Managing cancer care during the COVID-19 pandemic: Agility and collaboration toward a common goal cms-releases-recommendations-adult-elective-surgeriesnon-essential-medical-surgical-and-dental Palliative radiotherapy for oncologic emergencies in the setting of COVID-19: Approaches to balancing risks and benefits Prostate cancer radiotherapy recommendations in response to COVID-19 Breast radiotherapy under COVID-19 pandemic resource constraints e approaches to defer or shorten treatment from a Comprehensive Cancer Center in the United States Effect of tumor dose, volume and overall treatment time on local control after radiochemotherapy including MRI guided brachytherapy of locally advanced cervical cancer Three-dimensional high dose rate intracavitary image-guided brachytherapy for the treatment of cervical cancer using a hybrid magnetic resonance imaging/computed tomography approach:
    keywords: brachytherapy; cancer; covid-19; dose; patients; rate; treatment
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        item: #1097 of 7819
          id: cord-261006-2xh3f07i
      author: Dong, Zhiyong
       title: Recommendations to Manage Patients for Bariatric Surgery in the COVID-19 Pandemic: Experience from China
        date: 2020-06-06
       words: 1367
      flesch: 40
     summary: key: cord-261006-2xh3f07i authors: Dong, Zhiyong; Zhang, Peng; Zhu, Jiangfan; Bai, Jie; Parmar, Chetan; Chen, Wenhui; Hu, Ruixiang; Wang, Jianxue; Chong, Tsz Hong; Jiang, Shuwen; Yang, Wah; Gao, Lilian; Chen, Xiaomei; Yang, Jingge; Xia, Zefeng; Tao, Kaixiong; Wang, Cunchuan title: Recommendations to Manage Patients for Bariatric Surgery in the COVID-19 Pandemic: Experience from China date: 2020-06-06 journal: Obes Surg DOI: 10.1007/s11695-020-04741-8 sha: doc_id: 261006 cord_uid: 2xh3f07i nan In our bariatric surgery department, we stopped elective bariatric surgeries in January to prepare for a possible influx of COVID-19 patients. Novel coronavirus (COVID-19) situation dashboard Obesity, fat mass and immune system: role for leptin Impact of obesity on influenza A virus pathogenesis, immune response, and evolution Minimally invasive surgery and the novel coronavirus outbreak: lessons learned in China and Italy Practical recommendations of the obesity management task force of the European Association for the Study of obesity for the post-bariatric surgery medical management ASMBS pediatric metabolic and bariatric surgery guidelines Nutritional recommendations for adult bariatric surgery patients: clinical practice A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version) Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019 Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
    keywords: covid-19; health; infection; patients; surgery
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        item: #1098 of 7819
          id: cord-261029-befymalm
      author: Sultan, Keith
       title: Review of inflammatory bowel disease and COVID-19
        date: 2020-10-07
       words: 3262
      flesch: 45
     summary: The authors observed an incidence of COVID-19 positive IBD patients in the cohort of 0.0025, which was similar to the current cumulative incidence of 0.0017 in France and Italy at that time. As such, the risk of COVID-19, virus related outcomes, and appropriate management of IBD patients during the global pandemic is of immediate concern to gastroenterologists worldwide.
    keywords: bowel; cases; covid-19; disease; ibd; patients; sars
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        item: #1099 of 7819
          id: cord-261057-pq0gkwiu
      author: García-Reyna, Benjamín
       title: Fear of COVID-19 Scale for Hospital Staff in Regional Hospitals in Mexico: a Brief Report
        date: 2020-11-04
       words: 3868
      flesch: 43
     summary: possible suicide prevention strategies The immediate psychological and occupational impact of the 2003 SARS outbreak in a teaching hospital The brain on stress: vulnerability and plasticity of the prefrontal cortex over the life course Fear of the coronavirus (COVID-19): Predictors in an online study The effects of safety behaviors on health anxiety: an experimental investigation Assessing psychological response to the COVID-19: the fear of COVID-19 scale and the COVID stress scales Assessing the psychological response to the COVID-19: a response to Bitan et al. 'Fear of COVID-19 scale: psychometric characteristics, reliability and validity in the Israeli population Mental health and the COVID-19 pandemic COVID-19 and mental health: a review of the existing literature Psychological distress and signs of post-traumatic stress in response to the COVID-19 health emergency in a Mexican sample COVID-19 fear in Eastern Europe: validation of the fear of COVID-19 scale Por COVID-19, lanzan cloro a médicos, los insultan, les niegan transporte público Psychometric validation of the Bangla fear of COVID-19 scale: confirmatory factor analysis and Rasch analysis Adaptation of the Fear of COVID-19 Scale: its association with psychological distress and life satisfaction in Turkey Coronavirus (COVID-19)-Comunicado Técnico Diario COVID-19 pandemic: Responding to the challenge of global shortage of personal protective equipment Validation and psychometric evaluation of the Italian version of the fear of COVID-19 scale The biology of fear-and anxiety-related behaviors Fighting the SARS epidemic in Taiwan: a nursing perspective A longitudinal study on the mental health of general population during the COVID-19 epidemic in China Evaluation of the English version of the fear of COVID-19 scale and its relationship with behavior change and political beliefs Social capital and sleep quality in individuals who selfisolated for 14 days during the coronavirus disease 2019 (COVID-19) outbreak in January 2020 in China Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Conflict of Interest All authors declare that they have no conflict of interest. There was no significant effect of work shift on fear score (F(3, 2856)
    keywords: covid-19; fcv-19s; fear; health; hospital; personnel; scale; study
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        item: #1100 of 7819
          id: cord-261062-9zhe3ejy
      author: Zhu, Shu-Ting
       title: Utility of Point-of-Care Lung Ultrasound for Clinical Classification of COVID-19
        date: 2020-09-21
       words: 2748
      flesch: 45
     summary: This kind of classification of LUS scores can effectively stratify COVID-19 pneumonia severity and helpfully guide clinical monitoring. There were dramatic differences in LUS (p<0.001) among the three groups, and LUS scores (r=0.754) correlated positively with clinical severity (p<0.01).
    keywords: covid-19; lung; lus; patients; study
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        item: #1101 of 7819
          id: cord-261070-cvj1t0gi
      author: Zhang, Xue
       title: ACEI/ARB Use and Risk of Infection or Severity or Mortality of COVID-19: A Systematic Review and Meta-analysis
        date: 2020-05-15
       words: 2983
      flesch: 41
     summary: Three studies reported the susceptibility of COVID-19 in relation to ACEI/ARB use; the combined OR of COVID-19 risk was 0.99 (95% CI, 0.95-1.04), no heterogeneity was observed among the studies (I 2 = 0%, P = 0.504; Table 2 ). . However, these potential confounders considered in the most of included studies.
    keywords: acei; arb; covid-19; mortality; patients; risk; studies
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        item: #1102 of 7819
          id: cord-261075-wqtxhiy8
      author: Zhang, Meng
       title: The nervous system——a new territory being explored of SARS-CoV-2
        date: 2020-10-28
       words: 3726
      flesch: 28
     summary: People are generally susceptible to SARS-CoV-2 (18) . The existing researches mainly focus on SARS-CoV. In 2004, the virus RNA was detected in the cerebrospinal fluid of a SARS patient, which led to the scientists' suspicion that SARS-CoV was neuroinvasive (29) .
    keywords: acute; coronavirus; cov-2; covid-19; nervous; patients; respiratory; sars; system
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        item: #1103 of 7819
          id: cord-261086-pwgsl32m
      author: Aigner, Clemens
       title: COVID-19 in a lung transplant Recipient
        date: 2020-04-13
       words: 479
      flesch: 39
     summary: While older patients (above 50 years old) and patients presenting coexisting disorders are more prone to suffer from severe disease, data on disease presentation and evolution in immunocompromised patient is scarce. Whether Covid-19 is more severe or probably mitigated due to the effects of the immunosuppression on virus replication in patient after solid organ transplantation is still unknown but recovery was so far possible in most reported cases, although some anecdotal unpublished reports from Italy suggest a higher morbidity in older transplant recipients.
    keywords: covid-19; patients
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        item: #1104 of 7819
          id: cord-261105-hydccq8m
      author: Wang, Chongying
       title: The Impact of COVID-19 on Anxiety in Chinese University Students
        date: 2020-05-22
       words: 4756
      flesch: 52
     summary: The questionnaire package used in this cross-sectional study consisted of three components: a sociodemographic questionnaire that required each student to provide their sexes, year of study, city or province they were living, major and colleges, or schools; a measure of student anxiety (the Self-Rating Anxiety Scale); an open question about their most concern. University students are at high risk for depression and anxiety symptoms (Zivin et al., 2009; American College Health Association, 2018) and are exposed to multiple stressors unique to this developmental period (Beiter et al., 2015; Drake et al., 2016) .
    keywords: anxiety; china; covid-19; sas; students; study; university
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        item: #1105 of 7819
          id: cord-261113-v84rzhin
      author: Ferdinand, Keith C.
       title: Understanding African American COVID‐19 Severity and Mortality: Is Obesity the Key?
        date: 2020-08-04
       words: 1016
      flesch: 36
     summary: Global Health Observatory (GHO) data: overweight and obesity Prevalence of obesity and severe obesity among adults: United States Body mass index is associated with COVID-19 intensive care unit admission in African Americans Obesity and its implications for COVID-19 mortality Health equity considerations and racial and ethnic minority groups COVIDVIEW, a weekly surveillance summary of U.S. COVID-19 activity Covid-19 in critically ill patients in the Seattle region -case series Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission Obesity could shift severe COVID-19 disease to younger ages Obesity a risk factor for severe COVID-19 infection: multiple potential mechanisms Association of blood glucose control and outcomes in patients with COVID-19 and pre-existing type 2 diabetes Hypertension is associated with increased mortality and severity of disease in COVID-19 pneumonia: a systematic review, meta-analysis and meta-regression People at increased risk and other people who need to take extra precautions Guidance: staying alert and safe (social distancing). Similarly, in 265 patients (58% male) from several US university hospitals, obesity was a salient risk factor for severe COVID-19 disease.
    keywords: covid-19; disease; obesity; patients
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        item: #1106 of 7819
          id: cord-261141-w4bqp9xr
      author: Li, Jinpeng
       title: Clinical characteristics of emergency surgery patients-infected COVID-19 pneumonia in Wuhan, China
        date: 2020-05-19
       words: 2079
      flesch: 49
     summary: However no one focused on the clinical symptom of emergency surgery patients (ESP) with COVID-19 pneumonia. Although these reports investigated the risk for the healthcare workers and also made the stringent relative procedure, no one focused on the risk of emergency surgery patients (ESP) with COVID-19 pneumonia.
    keywords: care; covid-19; esp; patients; pneumonia
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        item: #1107 of 7819
          id: cord-261173-lnjh56ts
      author: Misra-Hebert, Anita D.
       title: Impact of the COVID-19 Pandemic on Healthcare Workers’ Risk of Infection and Outcomes in a Large, Integrated Health System
        date: 2020-09-01
       words: 3584
      flesch: 38
     summary: The neighborhood characteristic of population density as measured per square kilometer was similar for tested HCW vs. non-HCW while the population per housing unit was slightly higher. However, the overlap propensity score weighted proportions were 8.9 vs. 7.7 for HCW vs. non-HCW having a positive test with weighted odds ratio (OR) 1.17, 95% confidence interval (CI) 0.99–1.38.
    keywords: covid-19; hcw; health; non; patient; proportion; risk; vs.
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        item: #1108 of 7819
          id: cord-261174-jws90odd
      author: Tekbali, Asma
       title: Pregnant versus non-pregnant SARS-CoV-2 and COVID-19 Hospital Admissions: The first 4 weeks in New York
        date: 2020-04-15
       words: 146
      flesch: 41
     summary: The IRB determined that this study did not meet the definition of 34 human subject research and that, therefore, no IRB review was required. COVID-19) and Pregnancy: What obstetricians 84 need to know COVID-19) Pandemic and Pregnancy COVID-19 in pregnant women. The Lancet Infectious disease Management of pregnant women infected with COVID-19 The Lancet Infectious Diseases
    keywords: covid-19
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        item: #1109 of 7819
          id: cord-261192-yzw2bm13
      author: Sun, Jia-Kui
       title: Acute gastrointestinal injury in critically ill patients with COVID-19 in Wuhan, China
        date: 2020-10-21
       words: 3755
      flesch: 53
     summary: AGI grade I was defined as an increased risk of developing gastrointestinal dysfunction or failure (a self-limiting condition); AGI grade II was defined as gastrointestinal dysfunction (a condition that requires interventions); AGI grade III was defined as gastrointestinal failure (GI function cannot be restored with interventions); AGI grade IV was defined as marked gastrointestinal failure (a condition that is immediately life-threatening) We divided the patients into four groups based on the AGI grades: No AGI (n = 11), AGI grade I (n = 30), AGI grade II (n = 35), and AGI grade III to IV (n = 7).
    keywords: agi; covid-19; grade; incidence; injury; mortality; patients
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        item: #1110 of 7819
          id: cord-261222-762nqkbg
      author: Sachdeva, Sonali
       title: Admission Hyperglycemia in Non-diabetics Predicts Mortality and Disease Severity in COVID-19: a Pooled Analysis and Meta-summary of Literature
        date: 2020-10-12
       words: 2847
      flesch: 42
     summary: Studies have shown that COVID-19 patients with hyperglycemia are older compared with those with normal blood glucose levels. Men comprised a larger proportion of COVID-19 patients presenting with impaired fasting glucose, compared with those without hyperglycemia (55% vs 34%).
    keywords: covid-19; diabetes; fasting; glucose; hyperglycemia; patients
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        item: #1111 of 7819
          id: cord-261228-o80y5cic
      author: Jorge, D. C. P.
       title: Assessing the nationwide impact of COVID-19 mitigation policies on the transmission rate of SARS-CoV-2 in Brazil
        date: 2020-06-28
       words: 6412
      flesch: 47
     summary: In this work we analyzed the effects of 547 published governmental interventions, and population adherence thereof, on the dynamics of COVID-19 cases across all 27 Brazilian states, with emphasis on state capitals and remaining inland cities. In this work, we comparatively analyze the evolution of the COVID-19 transmission rate and reproductive number in all 27 Brazilian states, with emphasis on state capitals and remaining inland cities, establishing links with measures of governmental restrictions (NPIs) implemented in each region together with the human behaviour response, particularly the adherence to recommendations of social distancing.
    keywords: capitals; cities; covid-19; index; license; measures; medrxiv; population; preprint; states
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        item: #1112 of 7819
          id: cord-261256-iwdusvrw
      author: Gandolfi, Alberto
       title: Planning of school teaching during Covid-19
        date: 2020-10-01
       words: 8614
      flesch: 56
     summary: The conclusion is that, except in the extreme situations of almost complete elimination of Covid-19, or uncontrollable outbreak, the number of cases registered in a fully open school is likely to raise concerns from authorities before the end of the second month of school opening in any reasonable scenario; this is very likely to lead to the application of containment measures to the school, such as a forced, unplanned remote teaching. If one of the weeks for which remote teaching is planned by the optimal solution is instead changed to an in-class week, then the increment in the number of cases due to school opening ranges from an extra 72% to an extra 78%, compared to the extra 68% of the optimal solution.
    keywords: cases; class; days; number; opening; remote; school; teaching
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        item: #1113 of 7819
          id: cord-261270-jkm9c5yv
      author: Annweiler, Cédric
       title: National French survey of COVID-19 symptoms in people aged 70 and over
        date: 2020-06-18
       words: 1710
      flesch: 47
     summary: Symptoms of COVID-19 among older adults: systematic review of biomedical literature Coronavirus Disease 2019 in elderly patients: characteristics and prognostic factors based on 4-week follow-up Clinical characteristics and outcomes of older patients with coronavirus disease 2019 (COVID-19) in Wuhan, China (2019): a single-centered, retrospective study Novel Coronavirus Infection (COVID-19) in Humans: A Scoping Review and Meta-Analysis Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis Clinical characteristics of hospitalized patients with SARS-CoV-2 infection: A single arm meta-analysis Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms Leukocytes°/°mm 3 (n=17), mean ± SD 2 394 ± 881 2613±1174 COPD: chronic obstructive pulmonary disease; ENT: ear nose and throat; GIR: iso resource group; N: total number of patient included in the study; n: number of patients according to the considered group; SD: standard deviation; y: years; Compared to previous meta-analyses in younger adults [5] [6] [7] , we found that older adults with COVID-19 often exhibit thermal dysregulation, which however results less often in hyperthermia (56% here versus 82%
    keywords: adults; covid-19
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        item: #1114 of 7819
          id: cord-261311-j6bmgmhz
      author: Parreiras Martins, Maria Auxiliadora
       title: Preparedness of pharmacists to respond to the emergency of the COVID-19 pandemic in Brazil: a comprehensive overview
        date: 2020-07-31
       words: 4312
      flesch: 32
     summary: Rev Bras Ter Intensiva Liver and kidney injuries in COVID-19 and their effects on drug therapy; a letter to editor COVID-19 and older adults: what we know New understanding of the damage of SARS-CoV-2 infection outside the respiratory system Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy A proposal for staging COVID-19 coagulopathy Heparin: effects upon the glycocalyx and endothelial cells The versatile heparin in COVID-19 Stratifying therapeutic enoxaparin dose in morbidly obese patients by BMI class: a retrospective cohort study Guidance on minimizing risk of drug-induced ventricular arrhythmia during treatment of COVID-19: a statement from the Canadian Heart Rhythm Society Antibiotic use in the intensive care unit: optimization and de-escalation COVID-19: the uninvited guest in the intensive care unit (ICU) implications for pharmacotherapy COVID-19 and the potential long-term impact on antimicrobial resistance Involving antimicrobial stewardship programs in COVID-19 response efforts: all hands on deck Coronavirus disease 2019 (COVID-19) and pregnancy: what obstetricians need to know Hyperinflammatory shock in children during COVID-19 pandemic Breastfeeding and respiratory antivirals: coronavirus and influenza COVID-19 and cancer: a comprehensive review A standardized, structured approach to identifying drug-related problems in the intensive care unit: FASTHUG-MAIDENS Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Prediction models for diagnosis and prognosis of COVID-19 infection: systematic review and critical appraisal The laboratory tests and host immunity of COVID-19 patients with different severity of illness Development and validation of a clinical risk score to predict the occurrence of critical illness in hospitalized patients with COVID-19 Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease COVID19 coagulopathy in Caucasian patients Atrial fibrillation: prevalence in a large database of primary care patients in Brazil Acknowledgements COVID-19 patients may present high risk in the use of medications and clinical pharmacists can contribute substantially as part of a multidisciplinary team to improve outcomes in drug therapy in severe and critical illness.
    keywords: brazil; care; coronavirus; covid-19; disease; drug; health; pandemic; patients; pharmacists; pharmacy; use
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        item: #1115 of 7819
          id: cord-261315-n8tnistv
      author: Palomar‐Lever, Andres
       title: Hepatic steatosis as an independent risk factor for severe disease in patients with COVID‐19: A computed tomography study
        date: 2020-08-04
       words: 3373
      flesch: 46
     summary: Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention Diabetes as a risk factor for greater COVID-19 severity and in-hospital death: a metaanalysis of observational studies Patients with diabetes are at higher risk for severe illness from COVID-19 Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association Mechanisms of NAFLD development and therapeutic strategies Nonalcoholic fatty liver disease Detrimental effects of metabolic dysfunction-associated fatty liver disease and increased neutrophil-to-lymphocyte ratio on severity of COVID-19 Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention Liver fat imaging-a clinical overview of ultrasound, CT, and MR imaging The diagnostic accuracy of US, CT, MRI and 1H-MRS for the evaluation of hepatic steatosis compared with liver biopsy: a meta-analysis Macrovesicular hepatic steatosis in living related liver donors: correlation between CT and histologic findings Nonalcoholic fatty liver disease The role of chest imaging in patient management during the COVID-19 pandemic: a multinational consensus statement from the Fleischner Society Chest CT severity score: an imaging tool for assessing severe COVID-19 Fleischner Society: glossary of terms for thoracic imaging Time course of lung changes at chest CT during recovery from coronavirus disease 2019 (COVID-19) Radiological Society of North America Expert Consensus Statement on reporting chest CT findings related to COVID-19. Thus, according to our results, the presence of HS as a marker of increased risk of CT severity score may be only applied to patients with moderate to severe HS (≥30%).
    keywords: covid-19; disease; liver; obesity; patients; risk; severity
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        item: #1116 of 7819
          id: cord-261328-prczsz9m
      author: Yassa, Murat
       title: How to perform and interpret the lung ultrasound by the obstetricians in pregnant women during the SARS-CoV-2 pandemic
        date: 2020-10-02
       words: 2153
      flesch: 41
     summary: Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection The Diagnosis of Pneumonia in a Pregnant Woman with coronavirus disease 2019 Using Maternal Lung Ultrasound Point-of-care lung ultrasound in patients with COVID-19-a narrative review How to perform lung ultrasound in pregnant women with suspected COVID-19 Lung Ultrasound Can Influence the Clinical Treatment of Pregnant Women With COVID-19 Effectiveness of a'fast lung ultrasound teaching program'for gynecologists/obstetricians dealing with pregnant women with suspicion of COVID-19 infection Advances in lung ultrasound A preliminary study on the ultrasonic manifestations of peripulmonary lesions of non-critical novel coronavirus pneumonia (COVID-19) Proposal for International Standardization of the Use of Lung Ultrasound for Patients With COVID-19: A Simple, Quantitative, Reproducible Method Practical approach to lung ultrasound Sonographic signs and patterns of COVID-19 pneumonia Chest Computed Tomography and Lung Ultrasound Findings in COVID-19 Pneumonia: In the era of COVID-19 outbreak Lung ultrasound in pregnant women during the COVID-19 pandemic: an interobserver agreement study among obstetricians Outcomes of universal SARS-CoV-2 testing program in pregnant women admitted to hospital and the adjuvant role of lung ultrasound in screening: a prospective cohort study The authors thank Taha Yusuf Kuzan MD (Radiologist) for his valuable contributions in the interpretation of the images.
    keywords: covid-19; lines; lung; lus; women
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        item: #1117 of 7819
          id: cord-261370-jp5sqqwc
      author: Bollag, Wendy B.
       title: Phosphatidylglycerol and Surfactant: A Potential Treatment for COVID-19?
        date: 2020-09-16
       words: 4105
      flesch: 27
     summary: Journal of leukocyte biology Phosphatidylglycerol inhibits toll-like receptor-mediated inflammation by danger-associated molecular patterns Soy phosphatidylglycerol reduces inflammation in a contact irritant ear edema mouse model in vivo Pathogen-associated molecular patterninduced TLR2 and TLR4 activation increases keratinocyte production of inflammatory mediators and is inhibited by phosphatidylglycerol 18:1/18:1-Dioleoyl-phosphatidylglycerol prevents alveolar epithelial apoptosis and profibrotic stimulus in a neonatal piglet model of acute respiratory distress syndrome Phosphatidylglycerol provides short-term prophylaxis against respiratory syncytial virus infection COVID-19: towards understanding of pathogenesis SARS-CoV replicates in primary human alveolar type II cell cultures but not in type I-like cells Innate immune response of human alveolar type II cells infected with severe acute respiratory syndrome-coronavirus Pathogenesis of COVID-19 from a cell biology perspective Role of lung surfactant in respiratory disease: current knowledge in large animal medicine Understanding the principle biophysics concepts of pulmonary surfactant in health and disease. A key role of pulmonary surfactant is to reduce surface tension and prevent alveolar atelectasis at end expiration.
    keywords: ards; covid-19; distress; inflammation; lung; patients; surfactant; syndrome; type
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        item: #1118 of 7819
          id: cord-261383-izd1vn6f
      author: Oleynick, Christopher
       title: Symptoms of Pleurisy as the Initial Presentation of COVID-19
        date: 2020-07-24
       words: 2035
      flesch: 47
     summary: CONCLUSIONS: I report a patient who experienced pleuritic chest pain from viral pleurisy that was the initial manifestation of COVID-19 which, to the best of my knowledge, has not yet been reported in the literature. I report a patient who experienced pleuritic chest pain as the initial manifestation of infection with COVID-19, who subsequently developed more typical features, including cough, fever, shortness of breath, and hypoxia.
    keywords: chest; covid-19; pain; patient; scan
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        item: #1119 of 7819
          id: cord-261420-8wavi5tk
      author: Nazarimehr, Fahimeh
       title: Prediction of bifurcations by varying critical parameters of COVID-19
        date: 2020-06-16
       words: 2491
      flesch: 50
     summary: In the interaction of various cities, each city can have various parameters. Dynamics of the system have various bifurcation points.
    keywords: bifurcation; cities; model; parameters
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        item: #1120 of 7819
          id: cord-261424-t0yulofo
      author: Feltman, Dalia M.
       title: Seeking Normalcy as the Curve Flattens: Ethical Considerations for Pediatricians Managing Collateral Damage of COVID-19
        date: 2020-06-26
       words: 4299
      flesch: 43
     summary: For those children who require alternative safe placements or children who need to be removed from a home due to maltreatment, foster parents and extended family members may be more hesitant to increase COVID-19 exposures by accepting new children and child protection caseworkers into their homes. This pandemic highlights long-standing deficiencies and inefficiencies in our current system of child health care.
    keywords: care; children; covid-19; families; health; home; needs; pandemic; patients; pediatricians; risk
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        item: #1121 of 7819
          id: cord-261435-wcn4bjnw
      author: Ren, Xianwen
       title: Large-scale single-cell analysis reveals critical immune characteristics of COVID-19 patients
        date: 2020-10-29
       words: 8612
      flesch: 49
     summary: We first analyzed the compositional changes of the broad categories of immune cells for 206 PBMCs in different COVID-19 patient groups. 499 500 Such interaction distinctions not only existed among epithelial cells, but also impacted their 501 interactions with immune cells.
    keywords: age; cells; cov-2; covid-19; covid-19 patients; cytokine; differences; disease; figure; patients; plasma; sars; subtypes; types
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        item: #1122 of 7819
          id: cord-261437-x2k9apav
      author: Li, D.
       title: Are Vapers More Susceptible to COVID-19 Infection?
        date: 2020-05-09
       words: 3024
      flesch: 43
     summary: With every one percent increase in weighted proportion of vapers in each state, the number of COVID-19 infected cases increase by 0.3139 (95% CI: 0.0554 - 0.5723) and the number of COVID-19 deaths increase by 0.3705 (95% CI: 0.0623 - 0.6786) in log scale in each US state. Whether electronic cigarette users (vapers) are more susceptible to COVID-19 infection is unknown.
    keywords: covid-19; deaths; number; preprint; state; vapers
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        item: #1123 of 7819
          id: cord-261439-xfsqzadd
      author: Sohal, Karpal Singh
       title: Oral and maxillofacial surgical services amid COVID-19 pandemic: perspective from Tanzania
        date: 2020-08-17
       words: 1839
      flesch: 43
     summary: The American Association of Oral and Maxillofacial Surgeons Approaches to the management of patients in oral and maxillofacial surgery during COVID-19 pandemic Maxillofacial trauma management during COVID-19: multidisciplinary recommendations Late reporting for health care among patients presenting with oral maxillofacial tumours or tumour-like lesions in Muhimbili National Hospital. As such, there is a need for having locally tailored standard guidelines for managing patients with oral and maxillofacial conditions during the COVID 19 pandemic in Tanzania.
    keywords: conditions; covid-19; disease; pandemic; patients
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        item: #1124 of 7819
          id: cord-261455-uejtwgar
      author: Roschewski, Mark
       title: Inhibition of Bruton tyrosine kinase in patients with severe COVID-19
        date: 2020-06-05
       words: 7687
      flesch: 33
     summary: It has been reported that COVID-19 patients can have a biphasic clinical course with deterioration following initial improvement, consistent with a delayed and exaggerated immune activation (2) (3) (4) . We next examined expression of IL-6 protein by immune cells in the blood of COVID-19 patient since the production of this cytokine is known to be increased by BTK activity in normal human monocytes/macrophages (Fig. S2 ).
    keywords: acalabrutinib; activation; blood; btk; cells; clinical; cohort; covid-19; il-6; monocytes; oxygen; patients; table; treatment; ventilation
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        item: #1125 of 7819
          id: cord-261470-sqxdwu6j
      author: Weichmann, Franziska
       title: Projected supportive effects of Pycnogenol® in patients suffering from multi-dimensional health impairments after a SARS-CoV2 infection
        date: 2020-10-09
       words: 5931
      flesch: 30
     summary: We propose that Pycnogenol® may be beneficial in supporting recovery and mitigating symptoms and long-term consequences resulting from a SARS-CoV2 infection in COVID-19 patients. This property of Pycnogenol ® should be helpful in COVID-19 patients as well.
    keywords: cells; clinical; coronavirus; cov2; covid-19; disease; effects; infection; patients; pycnogenol; sars; study; syndrome
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        item: #1126 of 7819
          id: cord-261471-3msk5ggc
      author: Whyte, Martin B.
       title: The contribution of diabetic micro-angiopathy to adverse outcomes in COVID-19
        date: 2020-05-13
       words: 1175
      flesch: 29
     summary: Covid-19 Does Not Lead to a Typical Acute Respiratory Distress Syndrome Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis Facing COVID-19 in the ICU: vascular dysfunction, thrombosis, and dysregulated inflammation Endothelial cell infection and endotheliitis in COVID-19 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes Effects of hypertension, diabetes and coronary heart disease on COVID-19 diseases severity: a systematic review and meta-analysis Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Analyses of data on patients with COVID-19 should include details of diabetes complications and age, to untangle the complex interaction between ethnicity, diabetes and COVID-19 outcomes.
    keywords: covid-19; diabetes; microvascular
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        item: #1127 of 7819
          id: cord-261473-162uk7wm
      author: Klimach, Anna
       title: Rash as a presenting complaint in a child with COVID‐19
        date: 2020-06-11
       words: 579
      flesch: 54
     summary: The adult literature describes erythematous rashes, chilblains, SARS-CoV-2 infection in children Varicella-like exanthem associated with COVID-19 in an 8-year-old girl: a diagnostic clue? COVID-19 and kawasaki disease: novel virus and novel case Cutaneous manifestations in COVID-19: a first perspective COVID-19 can present with a rash and be mistaken for dengue: petechial rash in a patient with COVID-19 infection This article is protected by copyright. We describe the case of a thirteen‐year‐old boy with confirmed COVID‐19 in the United Kingdom who presented with skin findings localized to the plantar aspects of the feet, axillae and lower limbs.
    keywords: covid-19; skin
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        item: #1128 of 7819
          id: cord-261485-0ke5nqy0
      author: Sabir, A. M.
       title: Effects of Anticoagulants and Corticosteroids therapy in patients affected by severe COVID-19 Pneumonia
        date: 2020-06-29
       words: 4666
      flesch: 52
     summary: It was also observed that severe COVID-19 patients had higher levels of IL-6, 18 , suggesting that the hypercoagulation status of COVID-19 patients may be related to the elevated levels of cytokines. Therefore, COVID-19 patients with exertional dyspnea with or without hypoxia should be admitted to hospitals, evaluated for pulmonary involvement clinically and radiologically, and treated early with anti-inflammatory and antiviral drugs.
    keywords: covid-19; days; oxygen; patients; pneumonia; preprint; treatment
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        item: #1129 of 7819
          id: cord-261512-eoqrqnl4
      author: Sneyd, J.Robert
       title: The impact of the COVID-19 pandemic on anaesthesia trainees and their training
        date: 2020-07-23
       words: 2688
      flesch: 38
     summary: key: cord-261512-eoqrqnl4 authors: Sneyd, J.Robert; Mathoulin, Sophie E.; O'Sullivan, Ellen P.; So, Vincent C.; Roberts, Fiona R.; Paul, Aaron A.; Cortinez, Luis I.; Ampofo, Russell S.; Miller, Caitlynn J.; Balkisson, Maxine A. title: The impact of the COVID-19 pandemic on anaesthesia trainees and their training date: 2020-07-23 journal: To better understand and to document these impacts, we contacted anaesthesia trainees and trainers across six continents and collated their experiences during the pandemic.
    keywords: anaesthesia; covid-19; health; impact; learning; pandemic; patient; trainees; training
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        item: #1130 of 7819
          id: cord-261558-szll3znw
      author: Serrano-Ripoll, M. J.
       title: Effect of a Mobile-based Intervention on Mental Health in Frontline Healthcare Workers Against COVID-19: Protocol for a Randomized Controlled Trial
        date: 2020-11-06
       words: 4821
      flesch: 40
     summary: Despite the increasing use of mobile health interventions to deliver mental health care, this area of research is still on its infancy. In addition, the study findings will help increase the scientific evidence concerning the impact of mental mHealth interventions on a specific population (HCWs) under a specific context (the health emergency caused by the COVID-19 pandemic); as well as, more generally, the evidence about the effectiveness of mHealth-an area of research still in its early stages, for which robust trials are urgently needed.
    keywords: app; covid-19; hcws; health; intervention; medrxiv; preprint; review; stress; study
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        item: #1131 of 7819
          id: cord-261577-h86kidhs
      author: Páramo, José A.
       title: Pulmonary Embolism, Pulmonary Microvascular Thrombosis, or Both in COVID-19?
        date: 2020-07-22
       words: 362
      flesch: 16
     summary: José A. Páramo https://orcid.org/0000-0003-1497-6242 Incidence of thrombotic complications in critically ill ICU patients with COVID-19 High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Acute pulmonary embolism in COVID-19 patients on CT angiography and Pathological findings of COVID-19 associated with acute respiratory distress syndrome Pathology of 2019 novel coronavirus pneumonia: a dynamic disease process Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis Endothelial cell infection and endotheliitis in COVID-19 Pulmonary embolism in COVID-19 patients: awareness of an increased prevalence. The fact that no systematic objective screening for VTE (CT pulmonary angiogram and/ or ultrasonography) has been applied in many circumstances and the low number of deep vein thrombosis associated with pulmonary embolism in COVID-19 patients suggest that they have intrapulmonary acute microvascular thrombosis rather than embolism.
    keywords: covid-19; pulmonary
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        item: #1132 of 7819
          id: cord-261581-2pgac304
      author: Olorunsaiye, Comfort Z.
       title: COVID-19 and Child Vaccination: A Systematic Approach to Closing the Immunization Gap
        date: 2020-09-15
       words: 1625
      flesch: 32
     summary: Our findings will be beneficial to public health decision makers as countries loosen pandemic control restrictions and accelerate efforts to re-establish and strengthen immunization services to prevent outbreaks of communicable diseases. We analyzed the retrieved information using two key themes: (1) provision of immunization services and (2) utilization of immunization services.
    keywords: covid-19; immunization; pandemic; services
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        item: #1133 of 7819
          id: cord-261599-ddgoxape
      author: Nabi, Khondoker Nazmoon
       title: Forecasting of COVID-19 pandemic: From integer derivatives to fractional derivatives
        date: 2020-09-21
       words: 6636
      flesch: 49
     summary: PRCC is a global sensitivity analysis method, which is used to quantify the relationship between model response function (outputs) and model parameters (sampled by Latin Hypercube Sampling method) in an outbreak setting [28] . In this paper, a new compartmental COVID-19 model has been studied rigorously with the help of Caputo fractional derivatives.
    keywords: caputo; cases; class; covid-19; derivative; disease; fractional; model; order
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        item: #1134 of 7819
          id: cord-261653-0vtghtp7
      author: Andersen, Kylie J.
       title: Recruitment Strategy for Potential COVID-19 Convalescent Plasma Donors
        date: 2020-09-21
       words: 1668
      flesch: 36
     summary: Rochester, Minnesota required a strategy to interface with the community of recovering COVID-19 patients and recruit eligible convalescent plasma donors. This strategy may be adopted by other institutions to rapidly increase convalescent plasma donor recruitment.
    keywords: blood; convalescent; covid-19; donor; patients; plasma
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        item: #1135 of 7819
          id: cord-261670-rd9uq6tc
      author: Stringer, Kathleen A.
       title: COVID‐19: The Uninvited Guest in the Intensive Care Unit — Implications for Pharmacotherapy
        date: 2020-05-04
       words: 2886
      flesch: 34
     summary: 16 They collectively recommend that these therapies neither be withheld nor added in COVID-19 patients based on lack of human data and preclinical data suggesting benefit from their use. Larger hospitals are also establishing dedicated respiratory infectious containment units specifically for the treatment of COVID-19 patients regardless of whether they require mechanical ventilation.
    keywords: china; clinical; covid-19; patients; studies; treatment; use
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        item: #1136 of 7819
          id: cord-261687-632r6uqe
      author: Xie, Z.
       title: Health and Demographic Impact on COVID-19 Infection and Mortality in US Counties
        date: 2020-05-11
       words: 2091
      flesch: 45
     summary: Therefore, the seniors need to be more careful to avoid COVID-19 infection due to their high fatality rate. By April 28, 2020, there are nearly three millions confirmed COVID-19 cases and over 200,000 confirmed deaths globally 2 .
    keywords: covid-19; license; preprint; rate
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        item: #1137 of 7819
          id: cord-261695-2zg3j4x8
      author: Boufkhed, Sabah
       title: Preparedness of African palliative care services to respond to the COVID-19 pandemic: A rapid assessment
        date: 2020-09-16
       words: 3970
      flesch: 44
     summary: While palliative care services have expertise and protocols to build 214 capacity among colleagues across the health system, they lack the resources to deliver this crucial 215 contribution of palliative care during public health emergencies. 216 To the best of our knowledge, this study is the first to provide a comprehensive assessment of the 217 preparedness and capacity of palliative care services to respond to a pandemic in palliative care (14) The use of the SmartSurvey platform has enabled a fast and user-friendly 228 data collection while preventing multiple completion from a single computer.
    keywords: african; care; covid-19; health; palliative; patients; preparedness; services; staff
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        item: #1138 of 7819
          id: cord-261711-nmmz9tke
      author: Verma, Surabhi
       title: Investigating the Emerging COVID-19 Research Trends in the Field of Business and Management: A Bibliometric Analysis Approach
        date: 2020-07-02
       words: 6288
      flesch: 38
     summary: This article contributes to research on COVID-19 by elucidating the theoretical evolution of COVID-19 research and its linkages with multiple economic, social, and technological factors. This study is an early attempt to gain perceptive insights into the intellectual structure of COVID-19 research in the arena of business using bibliometric analysis.
    keywords: analysis; business; covid-19; crisis; data; et al; impact; management; pandemic; research; risk; study; supply
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        item: #1139 of 7819
          id: cord-261771-43075ute
      author: Zhu, Zhen
       title: The psychological status of people affected by the COVID-19 outbreak in China
        date: 2020-05-28
       words: 2239
      flesch: 44
     summary: The participant in March have less psychological health problems than in February Medical staff were likely to have higher SCL-90 scores than general population Female was likely to have more psychological health problems than male None. Of the 922 participants, approximately 18.3% had psychological health problems.
    keywords: covid-19; health; population; problems; staff
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        item: #1140 of 7819
          id: cord-261834-x5ltmj30
      author: Guo, Cheng-Xian
       title: Epidemiological and clinical features of pediatric COVID-19
        date: 2020-08-06
       words: 3443
      flesch: 42
     summary: Although there are no clear guidelines for the treatment of pediatric COVID-19, our study suggests that the treatment measures for pediatric COVID-19 patients were not as complex as that of adult COVID-19 patients, but even relatively simple. However, few studies have focused on the epidemiological and clinical characteristics of pediatric COVID-19.
    keywords: children; covid-19; data; days; patients; sars; study
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        item: #1141 of 7819
          id: cord-261840-hk5zi1lj
      author: Bhumireddy, Jayachandra
       title: Challenges and possible solutions in dental practice during and post COVID-19
        date: 2020-10-07
       words: 1611
      flesch: 46
     summary: key: cord-261840-hk5zi1lj authors: Bhumireddy, Jayachandra; Mallineni, Sreekanth Kumar; Nuvvula, Sivakumar title: Challenges and possible solutions in dental practice during and post COVID-19 date: 2020-10-07 journal: Although various infection control protocols had have been recommended to avoid transmission of COVID-19 disease in dental practice (Meng et al. 2020; Peng et al. 2020) , it has been reported that COVID-19 can be spread through direct and indirect communication, predominantly through respiratory droplets, and spatter from saliva and blood (Meng et al. 2020; Mallineni et al. 2020 ) and this makes dentists in potentially high risk.
    keywords: covid-19; practice; transmission
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        item: #1142 of 7819
          id: cord-261860-gfcm0q3p
      author: Fersia, O.
       title: The Impact of COVID-19 Pandemic on Cardiology Services
        date: 2020-06-16
       words: 3859
      flesch: 61
     summary: For instance, the hospital telemetry system became supported by the cardiac physiologist, allowing critical care nurses to focus on looking after COVID-19 patients. However, there have been no studies in the UK looking at the effect of COVID-19 work pattern on the provision of cardiology services.
    keywords: e n; n t; o n
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        item: #1143 of 7819
          id: cord-261875-6sdqh9bl
      author: Feinman, Jared W.
       title: The Fellowship Experience in Adult Cardiothoracic Anesthesiology – strategies for applicants and fellows to navigate the coronavirus crisis
        date: 2020-05-08
       words: 3102
      flesch: 26
     summary: The current deadlines have not been extended due to COVID-19, although individual fellowship programs may adjust their timeline for review of applications and interview scheduling, depending on the pandemic intensity. The second principle underlines their joint commitment to the public to enhance the quality of this workforce through appropriate standards for physician certification and appropriate accreditation of training programs, including adult cardiothoracic anesthesiology.
    keywords: adult; anesthesiology; cardiothoracic; covid-19; crisis; fellowship; pandemic; program
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        item: #1144 of 7819
          id: cord-261891-yiiz9s53
      author: Czernichow, Sébastien
       title: Obesity doubles mortality in patients hospitalized for SARS‐CoV‐2 in Paris hospitals, France: a cohort study on 5795 patients
        date: 2020-08-20
       words: 2717
      flesch: 49
     summary: 5 About ten years ago, against the backdrop of the H1N1 influenza epidemic, it was clearly pointed out in a meta-analysis on more than 3000 individuals, that people with severe obesity had a two-fold increased risk for intensive care unit (ICU) admission and mortality, compared to counterparts without obesity. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Joint international consensus statement for ending stigma of obesity Obesity and emergency care in the French CONSTANCES cohort Body-mass index and mortality among adults with incident type 2 diabetes Obesity and site-specific nosocomial infection risk in the intensive care unit Obesity is associated with higher risk of intensive care unit admission and death in influenza A (H1N1) patients: a systematic review and metaanalysis Obesity is associated with severe forms of COVID-19 High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation Covid-19 in Critically Ill Patients in the Seattle Region -Case Series Initializing a hospital-wide data quality program.
    keywords: bmi; copyright; covid-19; data; mortality; obesity; patients; people
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        item: #1145 of 7819
          id: cord-261899-xv4ulh6u
      author: Gao, Yadong
       title: COVID-19: Risk factors for critical illness
        date: 2020-08-19
       words: 1087
      flesch: 41
     summary: The death rate of critical ill COVID-19 patients ranged from 26% [6] , 39% The reported risk factors associated with death rate of critical ill COVID-19 patients include male, older age (>65 years), higher Sequential Organ Failure Assessment score (SOFA), high blood d-dimer (>1000 ng/mL), cardiovascular comorbidities, higher concentrations of Interleuking-6 (IL-6)
    keywords: covid-19; patients; risk
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        item: #1146 of 7819
          id: cord-261967-10mbsqmo
      author: Xu, Stanley
       title: Estimating the Growth Rate and Doubling Time for Short-Term Prediction and Monitoring Trend During the COVID-19 Pandemic with a SAS Macro
        date: 2020-04-11
       words: 1920
      flesch: 62
     summary: Estimated growth rate with 95% CIs over time using death data from New York State. . This paper illustrates that death data can be used to estimate the growth rate and doubling time to aid predicting future deaths, hospitalizations and COVID-19 cases.
    keywords: covid-19; growth; license; preprint; time
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        item: #1147 of 7819
          id: cord-261971-rt6uo9pw
      author: Jaworsky, Bernadette Nadya
       title: The Politics of Blaming: the Narrative Battle between China and the US over COVID-19
        date: 2020-09-01
       words: 8262
      flesch: 55
     summary: Trump fired back within days, retweeting a message containing the term China virus, 13 invoking the popular conspiracy that the virus was leaked from a high-security biochemical lab in Wuhan, suggested already by US Senator Tom Cotton publicly in February. The short-term and long-term impact of COVID-19 on globalization Glorious memories of imperial China and the rise of Chinese populist nationalism Constructing a new type of great power relations Covid-19 in China: From Chernobyl moment to impetus for nationalism Her two most recent articles, featuring the cultural sociological analysis of media coverage on refugees entering the United States and Canada, have been published in 2019 in Nations and Nationalism and Journal of Immigrant & Refugee Studies Runya's research focuses on civil society, social governance, and international relations through cultural sociological lenses.
    keywords: 2020; actors; battle; china; chinese; coronavirus; covid-19; foreign; july; narrative; nationalism; performance; public; trump; virus; world
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        item: #1148 of 7819
          id: cord-261980-bm0benu2
      author: Cox, Mougnyan
       title: Neuroendovascular Treatment of Acute Stroke during Covid-19: A Guide from the Frontlines
        date: 2020-05-29
       words: 2756
      flesch: 42
     summary: This especially evident during the COVID-19 pandemic, a situation that has increased the demands on radiology nurses during neurointervention for stroke patients of unknown COVID-19 status (so-called patients under investigation for COVID-19 or PUI). In addition, our modified protocols for resource utilization and management of stroke patients with LVO were also reviewed and clarified.
    keywords: acute; care; covid-19; patients; room; stroke; thrombectomy
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        item: #1149 of 7819
          id: cord-261985-ezzcgy6z
      author: Musa, Saif A.
       title: COVID-19: Defining an invisible enemy within healthcare and the community
        date: 2020-06-08
       words: 686
      flesch: 40
     summary: The rates of HoHA and HoPHA COVID-19 cases per total number of hospital admissions during this period were 32 of 1,818 (1.76%) and 32 of 1,818 (1.76%), respectively. Our data demonstrate that healthcare-associated COVID-19 has contributed an important number of cases patients during the height of a pandemic.
    keywords: covid-19; days
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        item: #1150 of 7819
          id: cord-262010-y1hevlxd
      author: Zhang, Qiongshuai
       title: Efficacy of acupuncture and moxibustion in adjuvant treatment of patients with novel coronavirus disease 2019 (COVID-19): A protocol for systematic review and meta analysis
        date: 2020-07-10
       words: 1886
      flesch: 43
     summary: key: cord-262010-y1hevlxd authors: Zhang, Qiongshuai; Xu, Xiaohong; Sun, Shaoqian; Cao, Fang; Li, Jiannan; Qi, Xun; Ji, Guangcheng; Wang, Yufeng; Song, Bailin title: Efficacy of acupuncture and moxibustion in adjuvant treatment of patients with novel coronavirus disease 2019 (COVID-19): A protocol for systematic review and meta analysis date: 2020-07-10 journal: Medicine (Baltimore) DOI: 10.1097/md.0000000000021039 sha: doc_id: 262010 cord_uid: y1hevlxd BACKGROUND: so as to provide evidence-based medical support for A&M treatment of COVID-19.
    keywords: a&m; coronavirus; covid-19; disease; review; treatment
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        item: #1151 of 7819
          id: cord-262029-zzn74cjr
      author: Kang, Chang Kyung
       title: In vitro activity of lopinavir/ritonavir and hydroxychloroquine against severe acute respiratory syndrome coronavirus 2 at concentrations achievable by usual doses
        date: 2020-05-29
       words: 2580
      flesch: 45
     summary: However, the reduction in viral load by hydroxychloroquine treatment was not significant (hydroxychloroquine 1 μg/mL vs. no treatment, p = 0.341; hydroxychloroquine 2 μg/mL vs. no treatment, p = 0.894). Viral RNA load was significantly lower in the lopinavir/ ritonavir group than in the no-treatment group or hydroxychloroquine groups (all p < 0.001) (Fig. 2) .
    keywords: cov-2; hydroxychloroquine; lopinavir; ritonavir; sars
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        item: #1152 of 7819
          id: cord-262049-c8uzehft
      author: Li, Ruilin
       title: Anxiety and related factors in frontline clinical nurses fighting COVID-19 in Wuhan
        date: 2020-07-24
       words: 3643
      flesch: 55
     summary: To understand the psychologic state of the first cohort of frontline nurses in the designated hospitals in Wuhan city, we investigated and analyzed their anxiety and the related factors, hoping to provide data for the psychologic intervention of frontline and rescue nurses. Frontline nurses in hospitals treating COVID-19 in Hubei province in January 2020 and February 2020 were enrolled.
    keywords: anxiety; covid-19; frontline; nurses; patients; psychologic; time; work
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        item: #1153 of 7819
          id: cord-262069-j3x08scy
      author: Puglisi, Lisa B.
       title: Estimation of COVID-19 Basic Reproduction Ratio in a Large Urban Jail in the United States
        date: 2020-09-09
       words: 957
      flesch: 44
     summary: Thirty days after the COVID-19 outbreak began, 5.6 percent of those incarcerated and 7.8 percent of staff had symptomatic COVID-19 infections. Ann Epidemiol DOI: 10.1016/j.annepidem.2020.09.002 sha: doc_id: 262069 cord_uid: j3x08scy nan Jails are epicenters of COVID-19 transmission in the United States.
    keywords: covid-19; individuals
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        item: #1154 of 7819
          id: cord-262073-7bhoyg4o
      author: Tolu, Lemi Belay
       title: Managing Resident Workforce and Residency Training During COVID-19 Pandemic: Scoping Review of Adaptive Approaches
        date: 2020-08-10
       words: 2976
      flesch: 29
     summary: Types of record, author of the document, field of residency training, the domain of residency education, month and year of publication, and recommendations of the documents were extracted. Few residency programs suspend resident clinical teachings 9 while many residency training programs designed alternative innovative technologies to maintain resident clinical education during COVID-19 pandemic.
    keywords: covid-19; education; pandemic; programs; research; residency; residents; review; training
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        item: #1155 of 7819
          id: cord-262090-nbxzyjvf
      author: Acharya, Arpan
       title: SARS-CoV-2 Infection Leads to Neurological Dysfunction
        date: 2020-05-23
       words: 3438
      flesch: 40
     summary: While most person with COVID-19 respiratory disease demonstrate headache, nausea and vomiting, up to 40% present also experience dizziness, confusion, cerebrovascular disease, muscle pain, ataxia and seizures. S1 contains the receptor-binding domain (RDB) and S2 forms the spike protein stalk (Luytjes et al. 1987; Abraham et al. 1990 ).
    keywords: coronavirus; cov-2; covid-19; disease; infection; patients; sars; syndrome; virus
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        item: #1156 of 7819
          id: cord-262095-u3ns50lg
      author: Whyte, Richard I.
       title: Validation of an Intellectual Framework for Prioritizing Time-Sensitive Surgical Procedures During the COVID-19 Pandemic
        date: 2020-07-16
       words: 409
      flesch: 23
     summary: Although prioritizing surgical cases is an everyday occurrence in non-COVID-19 times, the current crisis presents unusual constraints related to limited resources, viral exposure to both patients and staff, and a rapidly changing environment related to personal protective equipment, COVID-19 testing, and redeployment of hospital staff. key: cord-262095-u3ns50lg authors: Whyte, Richard I. title: Validation of an Intellectual Framework for Prioritizing Time-Sensitive Surgical Procedures During the COVID-19 Pandemic date: 2020-07-16 journal: J Am Coll Surg DOI: 10.1016/j.jamcollsurg.2020.04.024 sha: doc_id: 262095 cord_uid: u3ns50lg nan In the recent article by Prachand and colleagues, 1 the authors pose a simple and practical way of prioritizing nonemergent surgical cases in the midst of the coronavirus disease (COVID-19) pandemic.
    keywords: covid-19
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        item: #1157 of 7819
          id: cord-262100-z6uv32a0
      author: Wang, Yuanyuan
       title: Changes in network centrality of psychopathology symptoms between the COVID-19 outbreak and after peak
        date: 2020-09-14
       words: 5427
      flesch: 44
     summary: Using the cutoff score of 5 (at least experiencing mild depression and anxiety symptoms), after the peak stage, 42.94% of the participants showed depression symptoms, which is significantly higher (χ 2 = 24.29, p < 0.001) than that in outbreak stage (36.14%). During the outbreak and after peak, the occurrence of either impaired motor skills with depression symptoms or restlessness with anxiety symptoms could increase the risk of activation for other mental disorders.
    keywords: anxiety; bridge; covid-19; depression; health; network; outbreak; peak; symptoms
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        item: #1158 of 7819
          id: cord-262104-oig3qrr7
      author: Brüssow, Harald
       title: COVID‐19: Test, Trace and Isolate‐New Epidemiological Data
        date: 2020-06-08
       words: 7130
      flesch: 50
     summary: One in ten of >1'300 accredited nursing facilities reported COVID-19 cases. The control measures that stopped the epidemic locally have included: intense infection surveillance of incoming travelers; isolation of COVID-19 cases in hospitals; contact tracing and quarantine in holiday camps; and school closure but no lock-down, thus preventing the crisis from having a negative economic impact.
    keywords: cases; china; cov-2; covid-19; deaths; epidemic; health; infection; influenza; number; population; rate; sars; transmission
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        item: #1159 of 7819
          id: cord-262119-s6hc7fxs
      author: Ostaszewski, Marek
       title: COVID-19 Disease Map, a computational knowledge repository of SARS-CoV-2 virus-host interaction mechanisms
        date: 2020-10-27
       words: 12366
      flesch: 31
     summary: COVID-19 pathways featured in the previous section cover mechanisms reported so far. By aligning our efforts, we strive to provide COVID-19 specific pathway models, synchronize content with similar resources and encourage discussion and feedback at every stage of the curation process.
    keywords: activation; acute; analysis; apoptosis; cell; community; coronavirus; cov-2; covid-19; covid-19 disease; data; diagrams; disease; disease map; expression; host; human; infection; interactions; interferon; map; mechanisms; modelling; models; pathway; patients; protein; response; sars; syndrome; systems; type
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        item: #1160 of 7819
          id: cord-262152-gdnc51m5
      author: Chaibi, Sayma
       title: Liver Function Test Abnormalities Are Associated With A Poorer Prognosis In Covid-19 Patients: Results Of A French Cohort
        date: 2020-10-19
       words: 2770
      flesch: 46
     summary: Most of liver injuries are mild and transient during COVID-19. It might contribute to liver injury and even liver failure in patients who are critically ill.
    keywords: covid-19; disease; liver; patients; study
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        item: #1161 of 7819
          id: cord-262169-5x2oop1g
      author: Alola, Andrew Adewale
       title: The nCOVID-19 and financial stress in the USA: health is wealth
        date: 2020-10-08
       words: 3188
      flesch: 39
     summary: By employing the empirical Markov switching regression approach and the compliments of cointegration techniques, the study establishes a two-state (stable and distressing) financial stress situation resulting from the effects of COVID-19 daily deaths, COVID-19 daily recovery, and the USA’ economic policy uncertainty. Similar to the impact of COVID-19 daily deaths on the Americans' financial stress, the degree of uncertainty in the country's economic policy is a significant determinant of financial stress.
    keywords: covid-19; daily; deaths; financial; pandemic; stress; usa
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        item: #1162 of 7819
          id: cord-262188-a20vb800
      author: Horisberger, Alice
       title: Impact of COVID-19 pandemic on SLE: beyond the risk of infection
        date: 2020-05-05
       words: 1108
      flesch: 42
     summary: With the aim to reduce contact exposure, telephonic visits are a reasonable first-step screening for stable patients, nevertheless faceto-face visit should not be precluded for SLE patients with active disease potentially requiring therapeutic changes. Transplant patients taking immunosuppressants do not appear more prone for severe COVID-19.
    keywords: covid-19; ifn; patients; sle
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        item: #1163 of 7819
          id: cord-262192-w86qc3fq
      author: Balkhair, Abdullah A.
       title: COVID-19 Pandemic: A New Chapter in the History of Infectious Diseases
        date: 2020-04-21
       words: 1105
      flesch: 47
     summary: The current COVID-19 pandemic and its dreadful global impact is a reminder of the potential detriment of emerging infectious diseases. Oman Med J DOI: 10.5001/omj.2020.41 sha: doc_id: 262192 cord_uid: w86qc3fq nan T hroughout history, infectious diseases have caused havoc among societies.
    keywords: covid-19; health; pandemic; world
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        item: #1164 of 7819
          id: cord-262198-3slh8aha
      author: Rossell, S.
       title: An overview of current mental health in the general population of Australia during the COVID-19 pandemic: Results from the COLLATE project
        date: 2020-07-18
       words: 5110
      flesch: 48
     summary: key: cord-262198-3slh8aha authors: Rossell, S.; Neill, E.; Phillipou, A.; Tan, E.; Toh, W. L.; Van Rheenen, T.; Meyer, D. title: An overview of current mental health in the general population of Australia during the COVID-19 pandemic: Results from the COLLATE project date: 2020-07-18 journal: nan DOI: 10.1101/2020.07.16.20155887 sha: doc_id: 262198 cord_uid: 3slh8aha The novel coronavirus disease (COVID-19) poses significant mental health challenges globally; however, to date, there is limited community level data. Risk factors: Measurement of risk factors were divided into four categories: Demographics including: age, gender, education, living situation, geographical location/state, whether born in Australia, ethnicity, and religion; Personal vulnerabilities including: being someone at increased mortality risk (e.g. immune-compromised, >60years), having lived experience of mental illness, being a carer of someone with a mental illness or special needs, and being a healthcare professional or 'essential' worker; Financial stresses: fortnightly take-home pay, cash savings, mortgage repayments/rent, self-employment, job loss, and occupation; Social distancing experiences: perceived positives of the situation, perception of government restrictions on mental health, perception of social distancing measures duration, and working from home.
    keywords: covid-19; data; emotions; health; medrxiv; permission; perpetuity; preprint; reuse
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        item: #1165 of 7819
          id: cord-262203-tcs36kp9
      author: Berghella, Vincenzo
       title: Attack on coronavirus disease 2019 from American Journal of Obstetrics & Gynecology MFM
        date: 2020-04-21
       words: 897
      flesch: 58
     summary: These early manuscripts highlight the importance of proper personal protective equipment (PPE) for everyone, both healthcare workers (HCWs) and patients, both in outpatient and inpatient settings, and of testing asymptomatic pregnant women presenting for care. I understood from them and Italian news, loud and clear, how bad COVID-19 was for humans, and for pregnant women, early on.
    keywords: covid-19; mfm; women
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        item: #1166 of 7819
          id: cord-262236-1lilrqts
      author: Capone, Stephen
       title: Characterization of Critically Ill COVID-19 Patients at a Brooklyn Safety-Net Hospital
        date: 2020-08-17
       words: 3449
      flesch: 38
     summary: We suggest that the efficacy of anticoagulation may correlate to the increased incidence of thrombotic events seen in COVID-19 patients, which have the potential to lead to major sequelae, including organ failure and potentially death Although there has been significant speculation that individual medical comorbidities may impact the outcomes of COVID-19 patients, we have been unable to identify any significant individual factor.
    keywords: comorbidities; covid-19; median; mortality; patients; survival
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        item: #1167 of 7819
          id: cord-262249-9jutus1c
      author: Eshraghian, Ahad
       title: Reduced rate of hospital admissions for liver-related morbidities during the initial COVID-19 outbreak
        date: 2020-06-29
       words: 761
      flesch: 37
     summary: key: cord-262249-9jutus1c authors: Eshraghian, Ahad; Taghavi, Alireza; Nikeghbalian, Saman; Malek-Hosseini, Seyed Ali title: Reduced rate of hospital admissions for liver-related morbidities during the initial COVID-19 outbreak date: 2020-06-29 journal: Lancet Gastroenterol Hepatol DOI: 10.1016/s2468-1253(20)30207-7 sha: doc_id: 262249 cord_uid: 9jutus1c nan Reduced rate of hospital admissions for liverrelated morbidities during the initial COVID-19 outbreak Complications of liver cirrhosis and acute hepatitis are major causes of liver-related morbidities that require hospital admission. Liver-related conditions were defined as: acute hepatitis requiring hospital admission; complications in liver transplant recipients; and complications of liver cirrhosis including gastrointestinal bleeding, spontaneous bacterial peritonitis, hepatorenal syndrome, hepatic encephalopathy, and diuretic resistant ascites.
    keywords: hospital; liver
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        item: #1168 of 7819
          id: cord-262278-7d6u2tbj
      author: Hashemi, Masoud
       title: Anestesia espinhal em pacientes com COVID-19, mais pesquisa é necessária
        date: 2020-04-24
       words: 768
      flesch: 35
     summary: [6, 7] Portanto, atenção especial à condição cardíaca do paciente antes da anestesia raquidiana é de particular importância para que medidas apropriadas possam ser tomadas para manter a estabilidade hemodinâmica do paciente e evitar hipotensão indesejada. Portanto, pacientes hemodinamicamente instáveis, pacientes com dificuldade respiratória grave ou com coagulopatia, por exemplo, não são bons candidatos a serem submetidos à anestesia raquidiana.
    keywords: anestesia; com; covid-19; pacientes; para; que
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        item: #1169 of 7819
          id: cord-262286-flc5f9wh
      author: Baral, S. D.
       title: The Relationship between the Global Burden of Influenza from 2017-2019 and COVID-19
        date: 2020-06-20
       words: 4281
      flesch: 50
     summary: Data were abstracted from FluNet, a global web-based tool developed by the World Health Organization for influenza virological surveillance, which captures weekly laboratory confirmed influenza cases. Since more temperate zones in the Northern and Southern Hemispheres have generally opposing seasonal influenza trends, we report influenza case counts by calendar year from January 1 to December 31; which also facilitates comparisons with COVID-19.
    keywords: burden; cases; countries; covid-19; influenza; preprint; regions
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        item: #1170 of 7819
          id: cord-262311-vdbk50pl
      author: Grant-Kels, Jane M.
       title: Response to “Risks of Hydroxychloroquine use for COVID-19 prophylaxis”
        date: 2020-04-26
       words: 318
      flesch: 23
     summary: These findings cast doubt on the effectiveness of HCZ prophylaxis. Risks of Hydroxychloroquine use for COVID-19 prophylaxis Does Hydroxychloroquine Combat COVID-19? A Timeline of Evidence Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: an observational study Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial Bell CL Hydroxychloroquine in the treatment of rheumatoid arthritis Hydroxychloroquine and Other Autoimmune Drugs Don't Fully Protect Against Coronavirus, Early Data Suggest
    keywords: hydroxychloroquine
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        item: #1171 of 7819
          id: cord-262343-oo55qvpk
      author: Sohal, Sandeep
       title: COVID-19 Presenting with Seizures
        date: 2020-05-01
       words: 717
      flesch: 43
     summary: Future therapies including the role of direct antiviral agents lopinavir/ritonavir, immunomodulators tocilizumab in combating the cytokine storm and treating/preventing encephalopathy in COVID-19 patients should be investigated further. Laboratory values on admission, neurological investigations, as well as review of current literature on COVID-19 encephalitis is provided.
    keywords: covid-19; patient; seizures
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        item: #1172 of 7819
          id: cord-262375-1ex2ow07
      author: Qun, Sen
       title: Neutrophil-to-Lymphocyte Ratios Are Closely Associated With the Severity and Course of Non-mild COVID-19
        date: 2020-09-02
       words: 5193
      flesch: 41
     summary: The diagnostic criteria for suspected cases of COVID-19 pneumonia included the following (4): (1) Epidemiological history included: (i) pre-onset history of travel or residence in Wuhan or other areas where local cases continue to spread, (ii) fever or respiratory symptoms in patients who were from Wuhan City or other areas with continued local spread and were exposed 14 days before onset, and (iii) a cluster or epidemiological association with COVID-19 infection; (2) the following clinical features were present: (i) fever, (ii) imaging features indicative of pneumonia, and (iii) a normal or decreased total number of white blood cells in the early stage of the disease or a reduced lymphocyte count; or (3) if there was any epidemiological history, a suspected case could be diagnosed in the presence of any two of the listed clinical manifestations. Cardiovascular disease and pulse are risk factors for COVID-19, which may suggest that cardiovascular disease has a critical impact on COVID-19 patient mortality (44) and requires more attention as a comorbidity.
    keywords: cells; covid-19; cytokines; disease; il-6; lrs; lymphocyte; patients; severity; system
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        item: #1173 of 7819
          id: cord-262399-yqtbhdwh
      author: English, W.
       title: Suspected appendicitis and COVID-19, a change in investigation and management—a multicentre cohort study
        date: 2020-11-09
       words: 3643
      flesch: 37
     summary: On 25 March 2020, Intercollegiate guidelines were published in the UK to promote safe surgical provision during the COVID-19 outbreak advocating non-operative management or avoidance of laparoscopy when surgery is essential. The primary outcome was the impact of the COVID-19 pandemic on the use of non-operative management in appendicitis.
    keywords: appendicitis; covid-19; management; pandemic; patients; surgery
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        item: #1174 of 7819
          id: cord-262403-qw06qqlw
      author: López, Luz Polo
       title: Cirugía de cardiopatías congénitas en España durante el estado de alarma por COVID-19
        date: 2020-07-03
       words: 2535
      flesch: 40
     summary: En resumen, hemos dado una respuesta rápida y eficaz a las necesidades de nuestros pacientes y de nuestros compañeros según la evolución de la pandemia. El manejo preoperatorio de los pacientes durante este periodo se debe mantener hasta el completo control de la pandemia, para prevenir contagios tanto de pacientes como de profesionales.
    keywords: actividad; cirugía; con; covid-19; del; durante; las; los; pacientes; pandemia; para; por; que; una
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        item: #1175 of 7819
          id: cord-262412-bs7quwov
      author: Kaya, Gürkan
       title: Clinical and Histopathological Features and Potential Pathological Mechanisms of Skin Lesions in COVID-19: Review of the Literature
        date: 2020-06-30
       words: 3365
      flesch: 24
     summary: In a recent report, the postmortem histology of COVID-19 patients revealed lymphocytic endotheliitis in lung, heart, kidney, liver and small intestine, a pathological picture reminiscent of what is seen in skin lesions, suggesting that SARS-CoV-2 infection facilitates the induction of endothelial inflammation in several organs as a direct consequence of viral involvement and of host inflammatory response [61] . The pathological mechanisms of skin lesions in COVID-19 patients remain poorly understood.
    keywords: cov-2; covid-19; infection; lesions; manifestations; patients; sars; skin
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        item: #1176 of 7819
          id: cord-262413-jm4qmpeg
      author: Mao, Suling
       title: Epidemiological analysis of 67 local COVID-19 clusters in Sichuan Province, China
        date: 2020-10-08
       words: 4072
      flesch: 43
     summary: Main presentations of confirmed cases involved in the clusters in Sichuan included fever, respiratory and systemic symptoms, basically corresponding to the reported clinical characteristics of COVID-19 cases, and no characteristic clinical symptom was seen The epidemiological characteristics of 67 local clusters of COVID-19 cases in Sichuan Province reported as of March 17, 2020 were described and analyzed.
    keywords: asymptomatic; cases; clusters; covid-19; disease; period; sichuan
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        item: #1177 of 7819
          id: cord-262428-erlmyzwn
      author: CABARKAPA, Sonja
       title: The psychological impact of COVID-19 and other viral epidemics on frontline healthcare workers and ways to address it: A rapid systematic review
        date: 2020-09-17
       words: 5593
      flesch: 46
     summary: A study 2 of 1,557 nurses identified three attitudinal factors J o u r n a l P r e -p r o o f (health fear, social isolation and job stress) mediated the association between contact with SARS patients and psychological stress. The Psychiatric quarterly Prevalence of psychological symptoms among Ebola survivors and healthcare workers during the 2014-2015 Ebola outbreak in Sierra Leone: a crosssectional study The psychological impact of the SARS epidemic on hospital employees in China: exposure, risk perception, and altruistic acceptance of risk Psychological impact of the 2015 MERS outbreak on hospital workers and quarantined hemodialysis patients Psychological effects of the SARS outbreak in Hong Kong on high-risk health care workers Psychological impact of the 2003 severe acute respiratory syndrome outbreak on health care workers in a medium size regional general hospital in Singapore Risk Perception and Impact of Severe Acute Respiratory Syndrome (SARS) on Work and Personal Lives of Healthcare Workers in Singapore
    keywords: covid-19; hcws; health; nurses; outbreak; stress; studies; study; workers
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        item: #1178 of 7819
          id: cord-262454-bccrvapy
      author: Szente Fonseca, Silvia Nunes
       title: Risk of Hospitalization for Covid-19 Outpatients Treated with Various Drug Regimens in Brazil: Comparative Analysis
        date: 2020-10-31
       words: 4704
      flesch: 44
     summary: We observed that outpatient hospitalizations of the larger group of suspected COVID-19 ER patients, from the same HMO database before vs after the protocol started, March-April vs May, decreased significantly, 23% vs 9%, and mortality declined from 1.75% to 1.39%. The comorbidity distributions of the various treatments as shown in Table 1 suggest that except for shortness of breath, patients not treated with HCQ or J o u r n a l P r e -p r o o f prednisone may have been slightly less symptomatic than treated patients.
    keywords: age; covid-19; disease; hcq; medications; patients; risk; treatment; use
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        item: #1179 of 7819
          id: cord-262467-epqqd8n8
      author: Chen, Jun
       title: COVID-19 infection: the China and Italy perspectives
        date: 2020-06-08
       words: 7608
      flesch: 41
     summary: Other symptoms including rhinorrhoea, sore throat, fatigue, dyspnea, muscle weakness, dizziness, and headache are also often reported in COVID-19 patients. As a viral pneumonia, respiratory tract specimens from COVID-19 patients are first of choice to collect for the detection of viral nuclear acid.
    keywords: cases; china; clinical; coronavirus; cov-2; covid-19; disease; hcq; infection; patients; plasma; sars; study; tests; treatment
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        item: #1180 of 7819
          id: cord-262470-nkql7h9x
      author: Muus, Christoph
       title: Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells
        date: 2020-04-20
       words: 17614
      flesch: 41
     summary: In order to avoid spurious associations in cell types with very few ACE2 + cells and due to very low expression of ACE2, we subsampled ACE2cells to the number of ACE2 + cells within each cell type and discarded cell types containing fewer than 5 cells expressing either ACE2 or fewer than 5 cells expressing the other gene being tested after the subsampling procedure. Focusing on pathogenesis, in addition to key subsets in the lung, airways and gut, we identified ACE2 + cells that co-express either TMPRSS2 or CTSL in diverse organs, many of which have been associated with severe disease.
    keywords: ace2; ace2 expression; age; airway; analysis; associations; at2 cells; cell types; cells; coronavirus; cov-2; covid-19; ctsl; data; data fig; datasets; expression; fig; genes; human; infection; lung; model; patients; programs; samples; sars; secretory; seq; sex; smoking; tissue; tmprss2; type
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        item: #1181 of 7819
          id: cord-262489-cecg3geg
      author: Zhao, Zhanqi
       title: COVID-19 pneumonia: phenotype assessment requires bedside tools
        date: 2020-05-29
       words: 893
      flesch: 45
     summary: The disease status of COVID-19 patients developed rapidly. Bedside tools such as EIT and ultrasound may play an important role in identifying different phenotypes for COVID-19 patients.
    keywords: covid-19; lung; patients
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        item: #1182 of 7819
          id: cord-262499-68vmdqky
      author: Bordi, Licia
       title: Frequency and Duration of SARS-CoV-2 Shedding in Oral Fluid Samples Assessed by a Modified Commercial Rapid Molecular Assay
        date: 2020-10-20
       words: 5043
      flesch: 40
     summary: Parallel testing of 337 OF and NPS samples showed highly concordant results (κ = 0.831; 95 % CI = 0.771–0.891), and high correlation of Ct values (r = 0.921; p < 0.0001). Prolonged viral RNA shedding was observed up to 100 days from symptoms onset (DSO), with 32% and 29% positivity observed in OF and NPS samples, respectively, collected between 60 and 100 DSO.
    keywords: cov-2; covid-19; nps; samples; sars; values
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        item: #1183 of 7819
          id: cord-262519-qjolkwsd
      author: Xiong, X.
       title: Are COVID-19 infected children with gastrointestinal symptoms different from those without symptoms? A comparative study of the clinical characteristics and epidemiological trend of 244 pediatric cases from Wuhan
        date: 2020-05-05
       words: 3545
      flesch: 62
     summary: As of to date, this pandemic has still not been well controlled, [1, 2, 3] Similar to the Severe Acute Respiratory Syndrome (SARS) in 2003, apart from respiratory manifestations, a proportion of COVID-19 patients also develop GI symptoms, such as diarrhea and vomiting. In order to ascertain what factors on admission could predict GI symptoms in COVID-19 patients, we employed univariate analysis.
    keywords: covid-19; license; patients; preprint; symptoms
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        item: #1184 of 7819
          id: cord-262520-480kgpp2
      author: Kim, Yun Jeong
       title: How to keep patients and staff safe from accidental SARS-CoV-2 exposure in the emergency room: Lessons from South Korea’s explosive COVID-19 outbreak
        date: 2020-07-30
       words: 3975
      flesch: 49
     summary: (5) A portable negative-pressure isolation chamber was employed for COVID-19 patients and for patients whose COVID-19 status had not been identified but who needed to be moved inside the hospital beyond the ER. Since the 31st Korean case, who was the first in Daegu, was diagnosed on February 18, 2020, the number of COVID-19 patients increased explosively because of a cluster infection among a religious group called Shincheonji, which accounted for~70% of the Daegu cases.
    keywords: covid-19; hours; outbreak; patients; period; sars; shutdown; tests
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        item: #1185 of 7819
          id: cord-262550-oip5m9br
      author: Kumar, S. Udhaya
       title: The Rise and Impact of COVID-19 in India
        date: 2020-05-22
       words: 2870
      flesch: 50
     summary: Currently, out of 32 states and eight union territories in India, 26 states and six union territories have reported COVID-19 cases. If the number of COVID-19 cases increases in the nation, it would be a catastrophe for India (22) .
    keywords: cases; china; coronavirus; covid-19; health; india; outbreak; sars
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        item: #1186 of 7819
          id: cord-262556-gpnp06je
      author: Behrens, Estuardo
       title: COVID-19: IFSO LAC Recommendations for the Resumption of Elective Bariatric Surgery
        date: 2020-08-22
       words: 3201
      flesch: 37
     summary: collaborative analyses of 57 prospective studies Closed system water trap for the evacuation of smoke and aerosols OBES SURG High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission [published online ahead of print Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City Obesity could shift severe COVID-19 disease to younger ages Obesity and COVID-19 severity in a designated hospital in Shenzhen Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City Influenza and obesity: its odd relationship and the lessons for COVID-19 pandemic Groups at higher risk for severe illness Surgical treatment of obesity and diabetes ASMBS position statement on long-term survival benefit after metabolic and bariatric surgery Metabolic surgery in the treatment algorithm for type 2 diabetes: a joint statement by international diabetes organizations Indications for surgery for obesity and weight-related diseases: position statements from the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) Consenso de cirugía metabólica en Argentina (Consensus of Metabolic Surgery in Argentina) Long-term effects of bariatric surgery on type II diabetes, hypertension and hyperlipidemia: a meta-analysis and meta-regression study with 5-year follow-up The effectiveness and risks of bariatric surgery: an updated systematic review and meta-analysis Long-term follow-up after bariatric surgery: a systematic review Bariatric surgery in class I obesity: a position statement from the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) Bariatric surgery: the indications in metabolic disease Obesity surgery score (OSS) for prioritization in the bariatric surgery waiting list: a need of public health systems and a literature review Bariatric surgery waiting lists in Spain What is the impact on the healthcare system if access to bariatric surgery is delayed? The resumption of elective BMS must be a priority maybe similar to oncological surgery, when hospitals reach phase I or II, treating obesity patients in a NON-COVID area, avoiding inadvertent intrahospital contagion from healthcare provider, patients, and relatives.
    keywords: covid-19; disease; hospital; obesity; pandemic; patients; risk; sars; surgery
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        item: #1187 of 7819
          id: cord-262575-06i2nv0t
      author: Caracciolo, Massimo
       title: Case Report: Canakinumab for the Treatment of a Patient With COVID-19 Acute Respiratory Distress Syndrome
        date: 2020-08-25
       words: 2166
      flesch: 33
     summary: SARS-CoV-2 infection is associated with high cytokine levels, including interleukin-6 and certain subsets of immune cells, in particular, NK, distinguished according to the cell surface density of CD56. The immune response, including the release of pro-inflammatory cytokines and activation of T cells, are essential for controlling the viral spread, inflammation, and tissue renewal (5, 6) .
    keywords: canakinumab; covid-19; cytokine; day; infection; patient; treatment
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        item: #1188 of 7819
          id: cord-262626-yk4e737w
      author: Favaloro, Emmanuel J.
       title: Recommendations for Minimal Laboratory Testing Panels in Patients with COVID-19: Potential for Prognostic Monitoring
        date: 2020-04-12
       words: 1169
      flesch: 33
     summary: The rationale for the listing is also provided and based on recent reports around clinical and laboratory features of COVID-19 affected patients. 4, 5 Based on our understanding of the emerging literature, we aim to provide in this short commentary a simple list (►Table 1) of laboratory tests, as may be recommended for patients with COVID-19 and to potentially assist in prognostic monitoring of such patients.
    keywords: coronavirus; covid-19; disease; patients
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        item: #1189 of 7819
          id: cord-262631-xslc6olc
      author: Slim, K
       title: La chirurgie digestive urgente, victime collatérale de la crise du Covid-19?
        date: 2020-04-06
       words: 462
      flesch: 52
     summary: non soumis à la pression du Covid-19. Journal de chirurgie viscerale DOI: 10.1016/j.jchirv.2020.04.001 sha: doc_id: 262631 cord_uid: xslc6olc nan ont insisté sur la place du traitement non chirurgical de l'appendicite aiguë non compliquée de l'adulte, comme une alternative à la chirurgie au cours de la crise sanitaire du Covid-19.
    keywords: covid-19
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        item: #1190 of 7819
          id: cord-262653-v1to1mrp
      author: Asad, H.
       title: Health Care Workers and Patients as Trojan Horses: a COVID19 ward outbreak
        date: 2020-07-04
       words: 3433
      flesch: 53
     summary: In total 23 out of 29 staff on the ward developed COVID-19 infection over a 14 day period. The significant number of staff cases is likely related to these factors along with the lack of universal use of personal protective equipment for patient care at this time.
    keywords: case; hospital; infection; staff; transmission; ward
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        item: #1191 of 7819
          id: cord-262673-j2ot35lt
      author: Ahmed-Hassan, Hanaa
       title: Innate Immune Responses to Highly Pathogenic Coronaviruses and Other Significant Respiratory Viral Infections
        date: 2020-08-18
       words: 8607
      flesch: 21
     summary: Furthermore, respiratory epithelial cells and lung macrophages are capable of secreting a broad range of chemokines like IL-8, Macrophage inflammatory protein-1 Interestingly, previous studies found rapid and significant restoration of lymphocyte subsets including, NK cells, in peripheral blood in patients recovering from the initial stages of SARS infection (249) .
    keywords: acute; cells; coronavirus; cov; cov-2; covid-19; disease; human; ifn; infection; influenza; lung; macrophages; mers; patients; response; role; sars; syndrome; type
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        item: #1192 of 7819
          id: cord-262681-2voe4r7f
      author: Kim, Moon-Young
       title: Proposal of the Autopsy Guideline for Infectious Diseases: Preparation for the Post-COVID-19 Era (abridged translation)
        date: 2020-08-14
       words: 6495
      flesch: 43
     summary: To assess the risk of infection caused by autopsy, the medical conditions of autopsy personnel should be checked periodically, especially after the autopsy of a high-risk person. The management of autopsy related facilities follows the standard autopsy protocol as mentioned above.
    keywords: autopsy; body; cases; covid-19; death; diseases; facilities; infection; personnel; risk; test
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        item: #1193 of 7819
          id: cord-262694-bltihsbt
      author: Sookramanien, Sabrina Pamela
       title: Provisions for Obstetrics and Gynaecology - letter to the editor on “Impact of the coronavirus (COVID-19) pandemic on surgical practice - Part 2 (surgical prioritisation)”: A correspondence
        date: 2020-06-02
       words: 1075
      flesch: 37
     summary: In response to concerns, the Royal College of Midwives (RCM) have lowered diagnosis threshold for investigating symptoms, consolidating their awareness of increased risk to BAME women. Prior to the COVID-19 outbreak, BAME women were five times more likely to die from complications related to pregnancy and childbirth.
    keywords: covid-19; pregnancy; services; women
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        item: #1194 of 7819
          id: cord-262699-e628ysw5
      author: Branstetter, S.
       title: The impact of the COVID-19 pandemic on families in Germany
        date: 2020-10-06
       words: 3544
      flesch: 53
     summary: Proportional odds logistic regression analyses were performed to investigate the associations between study region and survey items. The predictor variables comprised study region (Leipzig vs. Regensburg), sociodemographic variables (education, migration background), the occurrence of SARS-CoV-2 infections in family/friends, risk group members in family/friends and being in quarantine.
    keywords: covid-19; families; measures; pandemic; preprint; study
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        item: #1195 of 7819
          id: cord-262708-hctuxrw9
      author: Ramachandra, C.
       title: Outcomes of Cancer Surgery During the COVID-19 Pandemic: Preparedness to Practising Continuous Cancer Care
        date: 2020-10-19
       words: 2371
      flesch: 40
     summary: Deprioritisation of nonemergency clinical services and growing concerns of adverse outcomes of COVID-19 in cancer patients is having a deleterious impact across oncologic practice. The pandemic has led to massive redirection of health care resources to treat the surge of COVID-19 patients, hence delivery of health care to the nonCOVID-related diseases including cancer patients has been significantly disrupted.
    keywords: cancer; covid-19; pandemic; patients; surgeries; years
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        item: #1196 of 7819
          id: cord-262716-hea84shy
      author: Pourali, Fatemeh
       title: Relationship between blood group and risk of infection and death in COVID-19: a live meta-analysis
        date: 2020-08-11
       words: 3870
      flesch: 49
     summary: The estimated frequency of COVID-19 infection and death in terms of ABO blood group and the overall estimate of the odd ratio between blood group with COVID-19 infection and death was done with 95% confidence interval. key: cord-262716-hea84shy authors: Pourali, Fatemeh; Afshari, Mahdi; Alizadeh-Navaei, Reza; Javidnia, Javad; Moosazadeh, Mahmood; Hessami, Amirhossein title: Relationship between blood group and risk of infection and death in COVID-19: a live meta-analysis date: 2020-08-11 journal: New Microbes New Infect DOI: 10.1016/j.nmni.2020.100743 sha: doc_id: 262716 cord_uid: hea84shy Abstract Introduction
    keywords: abo; blood; blood group; covid-19; group; infection; results; studies
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        item: #1197 of 7819
          id: cord-262730-1dxeg8ci
      author: Barón-Sánchez, J.
       title: Smell and taste disorders in Spanish patients with mild COVID-19
        date: 2020-10-08
       words: 3510
      flesch: 49
     summary: Some authors suggest that smell disorders may be mediated by direct infection of the olfactory mucosa, which would result in destruction of olfactory sensory neurons; recovery would therefore be slower, with olfactory alterations lasting longer and even a risk of permanent deficits. Furthermore, recovery of olfactory function was faster than and independent of recovery of gustatory function in most cases; most individuals with smell disorders experienced complete recovery.
    keywords: cov-2; covid-19; olfactory; participants; patients; sars; smell; taste
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        item: #1198 of 7819
          id: cord-262780-ilu5oskk
      author: Sattui, Sebastian E.
       title: Swinging the pendulum: lessons learned from public discourse concerning hydroxychloroquine and COVID-19
        date: 2020-08-11
       words: 4658
      flesch: 42
     summary: Further studies assessing HCQ with or without AZM on QT prolongation in COVID-19 patients emerged [35] . Although the observational design had limitations, it's release was followed by articles in the press highlighting concerns of harm with HCQ use [40] .
    keywords: coronavirus; covid-19; data; drug; hcq; hydroxychloroquine; patients; public; study; treatment; trial; use
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        item: #1199 of 7819
          id: cord-262784-r9gq2oan
      author: Tian, Suochen
       title: Clinical Characteristics and Reasons for Differences in Duration From Symptom Onset to Release From Quarantine Among Patients With COVID-19 in Liaocheng, China
        date: 2020-05-12
       words: 3755
      flesch: 45
     summary: Patients in the >20-day group were older, and the time from onset to admission was longer, suggesting that although there was no specific antiviral drug for COVID-19, systematic supportive treatment administered after admission could improve outcomes, even among patients with mild and moderate disease. Front Med (Lausanne) DOI: 10.3389/fmed.2020.00210 sha: doc_id: 262784 cord_uid: r9gq2oan Objective: This study aimed to identify additional characteristics and features of coronavirus disease (COVID-19) by assessing the clinical courses among COVID-19 patients in a region outside Hubei province.
    keywords: characteristics; clinical; day; disease; group; patients; quarantine
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        item: #1200 of 7819
          id: cord-262786-otxpc46a
      author: Mohammadi, Soheil
       title: Understanding the Immunologic Characteristics of Neurologic Manifestations of SARS-CoV-2 and Potential Immunological Mechanisms
        date: 2020-09-01
       words: 6308
      flesch: 34
     summary: Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China Neurologic features in severe SARS-CoV-2 infection Brain MRI findings in patients in the intensive care unit with COVID-19 infection Brain MRI findings in severe COVID-19: a retrospective observational study Report of EEG finding on critically ill patients with COVID-19 Intact brain network function in an unresponsive patient with COVID-19 Neurochemical evidence of astrocytic and neuronal injury commonly The hypothalamus as a hub for SARS-CoV-2 brain infection and pathogenesis Cerebrovascular and neurological dysfunction under the threat of COVID-19: is there a comorbid role for smoking and vaping? Immediate and long-term consequences of COVID-19 infections for the development of neurological disease Cranial neuropathies and COVID-19: neurotropism and autoimmunity Large artery ischaemic stroke in severe acute respiratory syndrome (SARS) Is the collapse of the respiratory center in the brain responsible for respiratory breakdown in COVID-19 patients? Nervous system involvement after infection with COVID-19 and other coronaviruses The cognitive consequences of the COVID-19 epidemic: collateral damage? Several pathogenic mechanisms have been proposed for the neurological deficit in SARS-CoV-2: indirect CNS involvement through systemic inflammation, direct invasion of the virus into the CNS, multi-organ failure, hypoxia, sepsis, etc.
    keywords: brain; cells; cns; cov-2; covid-19; cytokine; disease; immune; infection; olfactory; patients; response; sars; virus
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        item: #1201 of 7819
          id: cord-262787-3a3c8ee1
      author: Ray, Debashree
       title: Predictions, role of interventions and effects of a historic national lockdown in India's response to the COVID-19 pandemic: data science call to arms
        date: 2020-04-18
       words: 7867
      flesch: 46
     summary: Our projections using current daily data on case counts until April 7 in India show that the lockdown, if implemented correctly in the end, has a high chance of reducing the number of COVID-19 cases in the short term and buy India invaluable time to prepare its healthcare and disease monitoring system. Objective: To study the short- and long-term impact of an initial 21-day lockdown on the total number of COVID-19 cases in India compared to other less severe non-pharmaceutical interventions using epidemiological forecasting models and Bayesian estimation algorithms; to compare effects of hypothetical durations of lockdown from an epidemiological perspective; to study alternative explanations for slower growth rate of the virus outbreak in India, including exploring the association of the number of cases and average monthly temperature; and finally, to outline the pivotal role of reliable and transparent data, reproducible data science methods, tools and products as we reopen the country and prepare for a post lock-down phase of the pandemic.
    keywords: cases; covid-19; data; health; india; license; lockdown; medrxiv; model; number; people; preprint; time
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        item: #1202 of 7819
          id: cord-262863-f07v5uk8
      author: Bertocchi, Ilaria
       title: The hidden role of NLRP3 inflammasome in obesity‐related COVID‐19 exacerbations: lessons for drug repurposing
        date: 2020-08-09
       words: 5448
      flesch: 13
     summary: A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 Activation of the TXNIP/NLRP3 inflammasome pathway contributes to inflammation in diabetic retinopathy: a novel inhibitory effect of minocycline The Antimalarial Chloroquine Suppresses LPS-Induced NLRP3 Inflammasome Activation and Confers Protection against Murine Endotoxic Shock A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases Baricitinib counteracts metaflammation, thus protecting against diet-induced metabolic abnormalities in mice Cyclosporine therapy in cytokine storm due to coronavirus disease 2019 (COVID-19) Angiotensin II mediates angiotensin converting enzyme type 2 internalization and degradation through an angiotensin II type I receptor-dependent mechanism Immunological and inflammatory functions of the interleukin-1 family The effect of obesity on lung function Antiinflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells Tofacitinib inhibits granulocyte-macrophage colony-stimulating factor-induced NLRP3 inflammasome activation in human neutrophils The role of annexin A1 in the modulation of the NLRP3 inflammasome Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents Mechanisms of disease: inflammasome activation and the development of type 2 diabetes Obesity Impairs the Adaptive Immune Response to Influenza Virus Azithromycin inhibits IL-1 secretion and non-canonical inflammasome activation Dexamethasone alleviate allergic airway inflammation in mice by inhibiting the activation of NLRP3 inflammasome Clinical Characteristics of Coronavirus Disease 2019 in China ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet Chloroquine protects mice from challenge with CpG ODN and LPS by decreasing proinflammatory cytokine release Inflammation, metaflammation and immunometabolic disorders Clinical features of patients infected with 2019 novel coronavirus in Wuhan Tranilast directly targets NLRP3 to treat inflammasome-driven diseases Obesity and the outcome of infection Obesity and the risk and outcome of infection Differential effects of inhibition of interleukin 1 and 6 on myocardial, coronary and vascular function Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation Delayed oseltamivir plus sirolimus treatment attenuates H1N1 virus-induced severe lung injury correlated with repressed NLRP3 inflammasome activation and inflammatory cell infiltration Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis Diet-induced obesity impairs the T cell memory response to influenza virus infection The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation Rapamycin regulates macrophage activation by inhibiting NLRP3 inflammasome-p38 MAPK-NFkappaB pathways in autophagy-and p62-dependent manners The Role of Interferons in Inflammation and Inflammasome Activation Obesity and respiratory hospitalizations during influenza seasons in Ontario, Canada: a cohort study NLRP3 inflammasome activation in inflammaging Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission Current laboratory diagnostics of coronavirus disease 2019 (COVID-19) NLRP3 inflammasome activation is involved in endothelial lysosome membrane permeabilization, cathepsin B release, impaired glycocalyx thickness (Ikonomidis et al., 2019) , thus further contributing to the enhanced susceptibility to cardiovascular injury.
    keywords: activation; cov-2; covid-19; et al; infection; inflammasome; inflammasome activation; inflammation; nlrp3; nlrp3 inflammasome; obesity; patients; response; sars
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        item: #1203 of 7819
          id: cord-262878-ygvbqmxd
      author: de Carranza, María
       title: Aortic thrombus in patients with severe COVID-19: review of three cases
        date: 2020-07-09
       words: 1900
      flesch: 36
     summary: An increase in the incidence of acute pulmonary thromboembolism (APE) has been recently reported in COVID-19 patients [11] . Different anticoagulant protocols are being used, not only between institutions but also between countries, as no real anticoagulant consensus has been defined for COVID-19 patients
    keywords: aortic; covid-19; dose; events; patients; thrombus
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        item: #1204 of 7819
          id: cord-262909-pixroj1k
      author: Wang, Zhao
       title: High Fluorescent Lymphocytes Are Increased in COVID‐19 Patients
        date: 2020-05-20
       words: 1377
      flesch: 60
     summary: blood lymphocytes are decreased in COVID-19 patients (Guan et al., 2020) . The mechanism of lymphopenia in COVID-19 patients is that lymphocytes, especially T cells, are attracted into the infection sites or killed by the coronavirus.
    keywords: covid-19; hfl; patients
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        item: #1205 of 7819
          id: cord-262910-hgmwmrtq
      author: Hornuss, D.
       title: Anosmia in COVID-19 patients
        date: 2020-05-03
       words: 1231
      flesch: 62
     summary: Conclusions: The majority of COVID-19 patients have an objective anosmia and hyposmia, which often occurs unnoticed. 3 Anosmia in COVID-19 patients -Manuscript -DW
    keywords: covid-19; patients
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        item: #1206 of 7819
          id: cord-262928-l2bqcd0l
      author: Guarisco, Gloria
       title: Covid-19 and diabesity: when a pandemia cross another pandemia
        date: 2020-07-14
       words: 2041
      flesch: 35
     summary: Data from the Intensive Care National Audit & Research Centre (ICNARC) report on COVID-19 in critical care of United Kingdom (March 27th 2020) described that 72.1% of 775 patients with confirmed COVID-19 were overweight or obese and that among patients with Body Mass Index (BMI) > 30 kg/m 2 who had undergone intensive care, 60.9% of them died. Extensive Chinese observational reports on confirmed Covid-19 cases indicated that among patients with the most severe form of disease the prevalence of diabetes was 12-16%
    keywords: care; covid-19; diabesity; diabetes; obesity; patients
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        item: #1207 of 7819
          id: cord-262936-yo6jf3ng
      author: Deng, Jia-gang
       title: Carry forward advantages of traditional medicines in prevention and control of outbreak of COVID-19 pandemic
        date: 2020-06-02
       words: 2944
      flesch: 32
     summary: It is the responsibility of our joint laboratory members to accelerate the development of traditional medicine research and industry. It is the responsibility of our joint laboratory members to accelerate the development of traditional medicine research and industry.
    keywords: chinese; control; cov-2; covid-19; development; epidemic; medicine; prevention; research; sars
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        item: #1208 of 7819
          id: cord-262945-zfcz0hpd
      author: Chow, Lai Chee
       title: Thrombosis and Bleeding as Presentation of COVID-19 Infection with Polycythemia Vera. A Case Report
        date: 2020-10-04
       words: 2050
      flesch: 52
     summary: It can also be used to monitor response to treatment of thrombosis in polycythemia vera patients in the context of COVID-19 infection. We describe a case of cerebral venous thrombosis in COVID-19 infection with underlying polycythemia vera a b Fig.
    keywords: covid-19; infection; patients; polycythemia; vera
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        item: #1209 of 7819
          id: cord-262954-saqo900k
      author: Esme, Mert
       title: Older Adults With Coronavirus Disease 2019; A Nationwide Study in Turkey
        date: 2020-09-01
       words: 4863
      flesch: 51
     summary: In univariate regression, these geriatric syndromes increase mortality risk in COVID-19 patients. Front Public Health Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis Epidemiology of Covid-19 in a Long-Term Care Facility in King County Twelve-year trends in the prevalence and risk factors of diabetes and prediabetes in Turkish adults Changes in hypertension prevalence, awareness, treatment, and control rates in Turkey from Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region COVID-19 spiraling of frailty in older Italian patients Frailty index predicts poor outcome in COVID-19 patients.
    keywords: age; covid-19; disease; group; mortality; patients; risk; study
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        item: #1210 of 7819
          id: cord-262987-7h91n9ro
      author: Bin Traiki, Thamer A.
       title: Impact of COVID-19 pandemic on patient satisfaction and surgical outcomes: A retrospective and cross sectional study
        date: 2020-08-21
       words: 3327
      flesch: 43
     summary: Therefore, it is important to understand its impact on various parameters of patient care as regards revised infrastructure and policies in hospitals during the pandemic. In light of the above, systematized research is needed to understand the change, if any, in the dynamics of patient care, satisfaction, and post-surgical outcomes with regards to revised infrastructure and policies in hospitals in the wake of infectious pandemics like COVID-19.
    keywords: care; covid-19; hospital; pandemic; patients; satisfaction; study
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        item: #1211 of 7819
          id: cord-263002-f3itn0sb
      author: Wagener, Frank A. D. T. G.
       title: Targeting the Heme-Heme Oxygenase System to Prevent Severe Complications Following COVID-19 Infections
        date: 2020-06-19
       words: 3947
      flesch: 34
     summary: We therefore postulate that free heme contributes to many of the inflammatory phenomena witnessed in critically ill COVID-19 patients, whilst induction of HO-1 or harnessing heme may provide protection. A central role for free heme in the pathogenesis of severe sepsis Heme-induced cell adhesion in the pathogenesis of sickle-cell disease and inflammation Heme protein-mediated renal injury: A protective role for 21-aminosteroids in vitro and in vivo There is blood in the water: Hemolysis, hemoglobin, and heme in acute lung injury Heme scavenging reduces pulmonary endoplasmic reticulum stress, fibrosis, and emphysema The role of red blood cells and cell-free hemoglobin in the pathogenesis of ARDS Cell-free hemoglobin: A novel mediator of acute lung injury Acute respiratory distress in adults Low levels of tissue factor lead to alveolar haemorrhage, potentiating murine acute lung injury and oxidative stress ARDS & Cell-Free Hemoglobin-The Ascorbic Acid Connection A Medical Worker Describes Terrifying Lung Failure From COVID-19 -Even in His Young Patients COVID-19 pneumonia with hemoptysis: Acute segmental pulmonary emboli associated with novel coronavirus infection Weakness and elevated creatinine kinase as the initial presentation of coronavirus disease 2019 (COVID-19)
    keywords: cell; cov-2; covid-19; disease; free; heme; ho-1; inflammation; patients; sars
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        item: #1212 of 7819
          id: cord-263035-eekytsst
      author: Hart, Alexander
       title: A Proposed COVID-19 Testing Algorithm
        date: 2020-06-24
       words: 3170
      flesch: 50
     summary: The purpose of this article is to propose an algorithm for COVID-19 testing that would allow for physical distancing to be scaled back in a stepwise manner, which limits ensuing infections and protects the capacity of the health care system. The framework recommends which groups to prioritize for COVID-19 testing; however, this guidance leaves much to be desired in its lack of specificity.
    keywords: algorithm; covid-19; distancing; health; population; testing
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        item: #1213 of 7819
          id: cord-263055-4f25h9l4
      author: Fogarty, Helen
       title: More on COVID‐19 coagulopathy in Caucasian patients
        date: 2020-05-25
       words: 1191
      flesch: 29
     summary: Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients S Definition of clinically relevant non-major bleeding in studies of anticoagulants in atrial fibrillation and venous thromboembolic disease in non-surgical patients: communication from the SSC of the ISTH Incidence of thrombotic complications in critically ill ICU patients with COVID-19 High risk of thrombosis in patients in severe SARS-CoV-2 infection: a multicenter prospective cohort study Thromboinflammation and the hypercoagulability of COVID-19 The weight-adjusted low molecular weight heparin (LMWH) thromboprophylaxis used in the study is that routinely used for hospital in-patients in our institution, consistent with national recommendations [3,4] With respect to the cohort of patients with COVID-19 enrolled in our study, it is important to highlight that 74% of patients received enoxaparin 40mg (4000 IU) subcutaneously once daily.
    keywords: coagulopathy; covid-19; infection; patients
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        item: #1214 of 7819
          id: cord-263057-1pty32l1
      author: Bhopal, Sunil
       title: Children's mortality from COVID-19 compared with all-deaths and other relevant causes of death: epidemiological information for decision-making by parents, teachers, clinicians and policymakers
        date: 2020-05-30
       words: 803
      flesch: 46
     summary: The situation in each country was almost identical, and in accordance with early data from China 8 i.e. COVID rarely kills children, even compared with influenza, against which many children are already vaccinated. Others have described collateral damage to children through social distancing measures 1 and questioned compatibility with the UN convention on the rights of the child.
    keywords: children; covid-19; data
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        item: #1215 of 7819
          id: cord-263061-ocplcdiv
      author: Rivetti, Luigi
       title: Management of Pacemaker Implantation during COVID-19 Infection
        date: 2020-10-24
       words: 1365
      flesch: 33
     summary: Furthermore, in our region, the management of COVID-19 patients in dedicated areas has been also assigned to general medical doctors [10] ; thus, it would have been hard for them if the specific management of a tPM is without any previous experience. Case Reports in Cardiology Several guidelines have already proposed different approaches about the management of AV conduction disorders patients; however, no real-world data are available until now in this specific setting.
    keywords: covid-19; implantation; infection; patient
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        item: #1216 of 7819
          id: cord-263064-n4c0m5hn
      author: Choudhury, Ivana
       title: COVID-19 as a Possible Cause of Functional Exhaustion of CD4 and CD8 T-cells and Persistent Cause of Methicillin-Sensitive Staphylococcus aureus Bacteremia
        date: 2020-07-04
       words: 2248
      flesch: 37
     summary: In one prospective study of 72 patients, patients with IE associated with MSSA infection significantly had a higher rate of major embolism than MRSA patients, as well as a significantly more unknown origin of bacteremia To our current knowledge, there is sparse clinical evidence suggesting the correlation between COVID-19 infection and its effect on the human immune system, making patients more susceptible to certain infections.
    keywords: abscess; cells; covid-19; mssa; patient; staphylococcus
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        item: #1217 of 7819
          id: cord-263066-umvojci8
      author: Smondack, P.
       title: Kinésithérapie et COVID-19 : de la réanimation à la réhabilitation à domicile. Synthèse des recommandations internationales
        date: 2020-10-13
       words: 5674
      flesch: 55
     summary: The hospital anxiety and depression scale Mild cognitive impairment in moderate to severe COPD: a preliminary study Guide de bonnes pratiques en période de COVID relatif à la prise en charge du patient en cabinet de ville Recommandations de la SF2H relatives à l'organisation du parcours des patients, à la protection des patients et des personnels à l'heure du déconfinement et de la reprise de l'activité médico-chirurgicale non COVID-19 en milieu de soins Compendium of physical activities: a second update of codes and MET values Arrêté du 23 mars 2020 prescrivant les mesures d'organisation et de fonctionnement du système de santé nécessaires pour faire face à l'épidémie de covid-19 dans le cadre de l'état d'urgence sanitaire Home-based rehabilitation for COPD using minimal resources: a randomised, controlled equivalence trial Comparison of a structured home-based rehabilitation programme with conventional supervised pulmonary rehabilitation: a randomised non-inferiority trial ATS statement: guidelines for the six-minute walk test An original field evaluation test for chronic obstructive pulmonary disease population: the six-minute stepper test Responsiveness and minimally important difference of the 6-minute stepper test in patients with chronic obstructive pulmonary disease Prise en charge ambulatoire des patients atteints de maladies respiratoires chroniques sévères Functional and postoperative outcomes after preoperative exercise training in patients with lung cancer: a systematic review and meta-analysis De plus, suite au déconfinement de la population et à la réouverture des cabinets libéraux, ces patients peuvent à nouveau être pris en charge en cabinet, dans des conditions d'hygiène adaptées à la pandémie.
    keywords: charge; covid-19; dans; des; doit; doivent; est; les; masque; par; pas; patients; pour; prise; que; respiratoire; sont; sur; une; être
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        item: #1218 of 7819
          id: cord-263080-c3bklv8s
      author: Inanc, Yusuf
       title: COVID-19 pneumonia following double-sleeve lobectomy for lung cancer
        date: 2020-09-30
       words: 1502
      flesch: 40
     summary: PCR testing confirmed COVID-19 infection and he was treated according to policies established by our nation’s health authority. Before referring him to oncology clinic for adjuvant chemotherapy, we confirmed his complete recovery from COVID-19 infection with three subsequent negative PCR testing, near total clearance of lung lesions on CT scan and the presence of acquired neutralizing antibodies against SARS-CoV-2 in his serum.
    keywords: covid-19; day; infection; lung
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        item: #1219 of 7819
          id: cord-263099-uhou04sp
      author: Marlais, Matko
       title: The severity of COVID-19 in children on immunosuppressive medication
        date: 2020-05-13
       words: 597
      flesch: 44
     summary: key: cord-263099-uhou04sp authors: Marlais, Matko; Wlodkowski, Tanja; Vivarelli, Marina; Pape, Lars; Tönshoff, Burkhard; Schaefer, Franz; Tullus, Kjell title: The severity of COVID-19 in children on immunosuppressive medication date: 2020-05-13 journal: Lancet Child Adolesc Health DOI: 10.1016/s2352-4642(20)30145-0 sha: doc_id: 263099 cord_uid: uhou04sp nan The number of people with coronavirus disease 2019 during this ongoing pandemic is rising rapidly. We therefore encourage readers of this Correspondence to report all children under their care who fulfil our inclusion criteria to our study. Estimates of the severity of coronavirus disease 2019: a model-based analysis Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study COVID-19 and paediatric inflammatory bowel diseases: global experience and provisional guidance We declare no competing interests.
    keywords: children; covid-19
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        item: #1220 of 7819
          id: cord-263127-zlenyzn9
      author: Alimohamadi, Yousef
       title: Estimate of the Basic Reproduction Number for COVID-19: A Systematic Review and Meta-analysis
        date: 2020-03-20
       words: 2586
      flesch: 39
     summary: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia Risk assessment of novel coronavirus COVID-19 outbreaks outside China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Pathological findings of COVID-19 associated with acute respiratory distress syndrome Real-time estimation of the risk of death from novel coronavirus (COVID-19) infection: inference using exported cases A novel coronavirus outbreak of global health concern The reproductive number of COVID-19 is higher compared to SARS coronavirus Complexity of the basic reproduction number (R0) Prevalence of needlestick and sharps injuries in the healthcare workers of Iranian hospitals: an updated meta-analysis. It also seems necessary to consider the reasons why high R0 values were reported in some studies.
    keywords: coronavirus; covid-19; novel; number; studies
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        item: #1221 of 7819
          id: cord-263191-osa3ylkl
      author: Pericàs, Juan M.
       title: Hospital at home for the management of COVID-19: preliminary experience with 63 patients
        date: 2020-09-29
       words: 1731
      flesch: 39
     summary: First, the sample size is small and the analysis is based on limited experience of patients collected during a short period of time as previously simultaneously HaH staff was responsible for adapting a Hotel for COVID-19 patients with the same admission criteria as in HaH. Second, the small number of events prevented us to analyze risk factors of readmission, new consultations to the hospital, or death. 95% with F i O2 < 0.35; C Reactive protein < 5 mg/dl or descending, normal LDH or descending, lymphocytes > 800 cells/mm 3 or ascending; no radiological progression of pneumonia; (4) admission from Emergency room: bilateral pneumonia in patient without high-risk factors (> 65 years old, hypertension, chronic obstructive pulmonary disease, cardiovascular disease, diabetes, cancer, and immunosuppression); respiratory infection without pneumonia, or unilobar pneumonia in patients with risk factors.
    keywords: admission; covid-19; hah; hospital; patients
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        item: #1222 of 7819
          id: cord-263214-h6lkvlj3
      author: Bassi, Massimiliano
       title: BEDSIDE TRANSCERVICAL-TRANSTRACHEAL POST-INTUBATION INJURY REPAIR IN A COVID-19 PATIENT
        date: 2020-04-22
       words: 1321
      flesch: 37
     summary: The management of COVID-19 patient can be challenging due to the risk of disease transmission to caregivers and epidemic spread. Management of COVID-19 patients represents a challenge especially during invasive airways interventions (2) .
    keywords: covid-19; injury; patient; tracheal
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        item: #1223 of 7819
          id: cord-263220-g721fj81
      author: Li, Xiaohu
       title: Helping the Radiologist: The Role of Scientific Journals to Help Prevent the Spread of COVID-19
        date: 2020-03-03
       words: 499
      flesch: 48
     summary: From February 4 until the present, Radiology has published CT findings of COVID-19 that can effectively guide our clinical work. CT Imaging of the 2019 Novel Coronavirus (2019-nCoV) Pneumonia Chest CT Findings in 2019 Novel Coronavirus (2019-nCoV) Infections from Wuhan, China: Key Points for the Radiologist The Many Faces of COVID-19:
    keywords: covid-19; imaging
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        item: #1224 of 7819
          id: cord-263231-tz97u731
      author: Muniz-Pardos, Borja
       title: Collateral Health Issues Derived from the Covid-19 Pandemic
        date: 2020-08-08
       words: 1892
      flesch: 34
     summary: Obesity could shift severe Covid-19 disease to younger ages Multidisciplinary research priorities for the Covid-19 pandemic: a call for action for mental health science Nowhere to hide: the significant impact of coronavirus disease 2019 (Covid-19) measures on elite and semi-elite South African athletes Elite athletes and Covid-19 lockdown: future health concerns for an entire sector Exercise and mental health Covid-19 lockdowns cause global air pollution declines with implications for public health risk The health effects of exercising in air pollution Patient Consent for Publication Not applicable. Such examples include hospital-athome programmes that provide individuals requiring hospitalisation for reasons other than Covid-19 constant health care through a combination of virtual and inperson visits [14] .
    keywords: covid-19; exercise; health; impact; lockdown
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        item: #1225 of 7819
          id: cord-263235-n8omnki4
      author: Hassan, Ansar
       title: Cardiac Surgery in Canada During the COVID-19 Pandemic: A Guidance Statement From the Canadian Society of Cardiac Surgeons
        date: 2020-04-08
       words: 2097
      flesch: 43
     summary: When it is feasible, cardiac surgical programs should make every effort to maintain areas within their institutions for cardiac surgery patients that are completely separate from patients with COVID-19, given the vulnerability of the average cardiac surgery patient (increased biological age and cardiovascular risk factors) Amid concerns over growing resource constraints, cardiac surgeons from across Canada have been forced to make drastic changes to their clinical practices.
    keywords: cardiac; covid-19; health; patients; surgeons
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        item: #1226 of 7819
          id: cord-263241-qzerj9bs
      author: Liu, Liu
       title: Clinical characteristics of hospitalized patients with 2019 novel coronavirus disease indicate potential proximal tubular dysfunction
        date: 2020-08-20
       words: 1543
      flesch: 48
     summary: People's Medical Publishing House Renal involvement and early prognosis in patients with COVID-19 pneumonia Hyponatremia and inflammation: the emerging role of interleukin-6 in osmoregulation Clinical characteristics of hospitalized patients with 2019 novel coronavirus disease indicate potential proximal tubular dysfunction Hypertension ( Compared with female patients (n = 52), male patients (n = 41) exhibited a significantly lower serum sodium level (136.8 ± 3.7 mmol/L vs. 139.0 ± 2.9 mmol/L; t = 3.191, P = 0.002) and eGFR (86.7 ± 20.6 mL·min À1 ·1.73 m À2 vs. 96.8 ± 19.7 mL·min À1 ·1.73 m À2 , t = 2.384, P = 0.019), and higher serum potassium (4.3 ± 0.5 mmol/L vs. 4.1 ± 0.4 mmol/L, t = À2.044, P = 0.044) and high-sensitivity C-reactive protein ( Only mild proteinuria (+ to ++) was found in all these 27 patients.
    keywords: patients; proteinuria; renal; study
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        item: #1227 of 7819
          id: cord-263244-dv2baj6j
      author: Farooqi, Kanwal M.
       title: Recommendations for Risk Stratified Use of Cardiac Computed Tomography for Congenital Heart Disease During the COVID-19 Pandemic
        date: 2020-06-09
       words: 1189
      flesch: 34
     summary: The use of CCT in CHD patients requires stratification to protect patients and staff, optimization of use of personal protective equipment (PPE) Nevertheless, a robust screening process for COVID -19 must be in place for CHD patients of any age presenting for CCT.
    keywords: cct; chd; covid-19; patients
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        item: #1228 of 7819
          id: cord-263258-qpzaehg0
      author: Montastruc, François
       title: Hepatic disorders with the use of remdesivir for coronavirus 2019 (COVID-19)
        date: 2020-07-25
       words: 871
      flesch: 34
     summary: ROR is a ratio similar in concept to the odds ratio in case-control studies and corresponds to the exposure odds among reported cases of hepatic disorders over the exposure odds among reported non-case b Cases were individual case safety reports containing any terms including the terminology Hepatobiliary disorders in the System Organ Class (SOC) view found in MedDRA dictionary https://www.meddra.org/ . c Non-cases were individual case safety reports containing all other adverse events reported linked with the respective drug.
    keywords: case; covid-19; remdesivir
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        item: #1229 of 7819
          id: cord-263267-oj7rmy8m
      author: Taccone, Fabio S
       title: Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base
        date: 2020-04-15
       words: 1155
      flesch: 31
     summary: Moreover, the inclusion and exclusion criteria were poorly described, most patients (69 of 75 [92%]) had a low National Early Warning Score, and the overall clinical outcome was similar to that reported for untreated patients with COVID-19. key: cord-263267-oj7rmy8m authors: Taccone, Fabio S; Gorham, Julie; Vincent, Jean-Louis title: Hydroxychloroquine in the management of critically ill patients with COVID-19: the need for an evidence base date: 2020-04-15 journal: Lancet Respir Med DOI: 10.1016/s2213-2600(20)30172-7 sha: doc_id: 263267 cord_uid: oj7rmy8m nan With the rapid spread of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), critical care physicians are seeing increasing numbers of patients with acute respiratory failure secondary to coronavirus disease 2019 (COVID-19) and reporting mortality rates of 40-65% for those requiring mechanical ventilation 1 -strikingly higher than the mortality rates reported for the more typical acute respiratory distress syndrome associated with other diseases.
    keywords: covid-19; hydroxychloroquine; patients
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        item: #1230 of 7819
          id: cord-263285-89zqgqx1
      author: Sethi, Sanjum S.
       title: Right Ventricular Clot in Transit in COVID-19: Implications for the Pulmonary Embolism Response Team
        date: 2020-05-29
       words: 1856
      flesch: 36
     summary: After presenting a case of right ventricular thrombus in a COVID-19 patient, we discuss the unique challenges in the workup and treatment of COVID-19 patients highlighting our COVID-19 modified pulmonary embolism response team (PERT) algorithm. Given this increased potential for hypercoagulable events, yet being mindful of exposure risks and practical considerations in caring for COVID-19 patients, we present the first report of a COVID-19 patient with clot in transit, along with an algorithm for diagnosing and treating venous thromboembolism in COVID-19 patients.
    keywords: acute; anticoagulation; covid-19; embolism; illness; patient
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        item: #1231 of 7819
          id: cord-263292-qjfe2t9v
      author: Sansone, A.
       title: Addressing male sexual and reproductive health in the wake of COVID-19 outbreak
        date: 2020-07-13
       words: 3913
      flesch: 27
     summary: The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis Effect of SARS-CoV-2 infection upon male gonadal function: a single center-based study COVID-19 and the endocrine system: exploring the unexplored Pathological findings in the testes of COVID-19 patients: clinical implications Low testosterone levels predict clinical adverse outcomes in SARS-CoV-2 pneumonia patients A critical analysis of the role of testosterone in erectile function: from pathophysiology to treatment-a systematic review The relationship between circulating testosterone and inflammatory cytokines in men Androgen sensitivity gateway to COVID-19 disease severity The interface of systems medicine and sexual medicine for facing non-communicable diseases in a gender-dependent manner ED2: erectile dysfunction = endothelial dysfunction SARS-CoV-2: a storm is raging From inflammation to sexual dysfunctions: a journey through diabetes, obesity, and metabolic syndrome Testosterone replacement therapy: the emperor's new clothes Effect of treatment with testosterone on endothelial function in hypogonadal men: a systematic review and meta-analysis Erectile dysfunction as a predictor of cardiovascular disease Why can patients with erectile dysfunction be considered lucky? Testicular function in COVID-19 patients requires careful investigation for the unclear association with testosterone deficiency and the possible consequences for reproductive health.
    keywords: cov-2; covid-19; disease; dysfunction; erectile; health; infection; pandemic; patients; sars; testosterone
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        item: #1232 of 7819
          id: cord-263300-qfquedya
      author: Ruthberg, Jeremy S.
       title: Geospatial analysis of COVID-19 and otolaryngologists above age 60()
        date: 2020-04-30
       words: 1783
      flesch: 48
     summary: The states with the highest ratios of confirmed COVID-19 cases to the number of total ENTs over 60 were New York, New Jersey, Massachusetts, and Michigan. The highest number of confirmed COVID-19 cases per ENT over 60 years old was New York (721) and the lowest was Hawaii (28).
    keywords: covid-19; ents; states; years
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        item: #1233 of 7819
          id: cord-263301-7gw6a6nv
      author: Sakelliadis, Emmanouil I.
       title: Impact of Covid-19 Lockdown on Characteristics of Autopsy Cases in Greece. Comparison between 2019 and 2020
        date: 2020-06-12
       words: 2451
      flesch: 47
     summary: Medicolegal investigation of confirmed COVID-19 cases usually falls out of the scope of forensic work, as the cause of death is already known. Social distancing during the COVID-19 pandemic: Staying home save lives, The American journal of emergency medicine Covid-19: UK starts social distancing after new model points to 260 000 potential deaths Covid-19: UK lockdown is crucial to saving lives, say doctors and scientists Social distancing to combat COVID-19: We are all on the front line Ministerial Decree for the Temporary Closing of Educational Institutions in Ministerial Decree for the Temporary Restriction of Operation of Private Businesses in Greece Ministerial Decree for the Temporary Restriction of Circulation of Citizens, in order to Counter the Risk of Coronavirus COVID-19 Dissemination/FEK B'/986 Guidelines for the Management of Dead Bodies, National Organization for Public Health Covid-19 epidemic in Italy: evolution, projections and impact of government measures The fast territorial expansion of the Covid-19 in Spain T. Investigation, First cases of coronavirus disease 2019 (COVID-19) in France: surveillance, investigations and control measures Covid-19: Why Germany's case fatality rate seems so low How Greece is beating coronavirus despite a decade of debt, The Guardian, The Guardian How Greece managed to flatten the curve, The Independent, The Independent Autopsy in suspected COVID-19 cases Myocardial Infarction and Covid-19 Reduction in ST-Segment Elevation Cardiac Catheterization Laboratory Activations in the United States during COVID-19 Pandemic Impact of Coronavirus Disease 2019 (COVID-19) Outbreak on ST-Segment-Elevation Myocardial Infarction Care in Hong Kong, China The authors had the following roles:
    keywords: cases; covid-19; deaths; greece; lockdown
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        item: #1234 of 7819
          id: cord-263308-q0iriid8
      author: Piano, Carla
       title: An Italian Neurology Outpatient Clinic Facing SARS-CoV-2 Pandemic: Data From 2,167 Patients
        date: 2020-05-29
       words: 3567
      flesch: 30
     summary: (4) highlighted the concern of neurologists for vulnerability to COVID-19 in patients with neurological diseases. Drug classes potentially interfering with SARS-CoV-2 (9) (i.e., ACEinhibitors, sartans, NSAIDs, steroids, immunosuppressant drugs) were distinguished from other pharmacological treatments, including specific treatments for neurological disease (i.e., levodopa, anticholinesterase drugs, memantine, xenazine, riluzole, botulinum toxin injections, and antiepileptic drugs).
    keywords: covid-19; disease; individuals; infection; patients; sample; symptoms; treatments; worsening
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        item: #1235 of 7819
          id: cord-263318-v079kur6
      author: Amaro, Rommie E.
       title: A Community Letter Regarding Sharing Biomolecular Simulation Data for COVID-19
        date: 2020-04-07
       words: 695
      flesch: 33
     summary: We, as a community, commit to the following principles and offer our support to others already working on open data efforts in the hope that others working on COVID-19 in biomolecular simulation and other areas will adopt similar best practices. We offer our support to others already working on open data efforts in the hope that others working on COVID-19 in biomolecular simulation and other areas will adopt similar best practices.
    keywords: covid-19; data; simulation
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        item: #1236 of 7819
          id: cord-263321-pzmo4hja
      author: Roach, P.
       title: Understanding the impact of the COVID-19 pandemic on well-being and virtual care for people living with dementia and care partners living in the community
        date: 2020-06-05
       words: 5113
      flesch: 41
     summary: In a letter in the Lancet, physicians from Wuhan province cited multiple barriers to good dementia care including difficulty adhering to social distancing and good hygiene, loss of services, and difficulty accessing telemedicine (Wang et al., 2020) . These interviews identified multiple adverse consequences of the public health measures implemented to contain spread of SARS-CoV-2, including loss of informal caregiving, lack of access to health care, and social isolation, contributing to burn out symptoms among care partners.
    keywords: care; covid-19; dementia; health; living; pandemic; partners; people; preprint
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        item: #1237 of 7819
          id: cord-263363-2um8ntvi
      author: de Havenon, Adam
       title: Excess neurological death in New York City after the emergence of COVID-19
        date: 2020-07-20
       words: 653
      flesch: 54
     summary: During 03/21/20-05/30/20, COVID-19 deaths averaged 1578 a week, failing to account for the entirety of excess death. Figure 1b shows the concept of excess non-COVID deaths, which averaged 1670/week during 03/21/20-05/30/20.
    keywords: covid-19; deaths
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        item: #1238 of 7819
          id: cord-263365-ymnbktm5
      author: Dube, Geoffrey K.
       title: COVID‐19 infection in pancreas transplant recipients
        date: 2020-06-09
       words: 2496
      flesch: 46
     summary: Several case reports and single-center series have described COVID-19 in transplant patients, with most series describing kidney transplant patients who were sick enough to require hospitalization. Diarrhea may be more commonly reported in transplant patients with COVID-19 than in the general population.
    keywords: covid-19; disease; patients; recipients; sars; transplant
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        item: #1239 of 7819
          id: cord-263371-1ozoq3hb
      author: Togun, Toyin
       title: Anticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes
        date: 2020-05-23
       words: 4025
      flesch: 52
     summary: TB control will focus on TB disease rather than prevention (such as the management of latent, non-transmissible TB infection). IPT works, and given that the under 5 year olds are particularly at risk of progressing to TB disease in its absence, the number of cases of childhood TB will most likely rise as a consequence.
    keywords: africa; care; control; covid-19; disease; health; patients
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        item: #1240 of 7819
          id: cord-263422-ojdcag0r
      author: Aranda-Abreu, Gonzalo Emiliano
       title: Response to: Amantadine, COVID-19 and Parkinsonism
        date: 2020-07-20
       words: 132
      flesch: 16
     summary: key: cord-263422-ojdcag0r authors: Aranda-Abreu, Gonzalo Emiliano title: Response to: Amantadine, COVID-19 and Parkinsonism date: 2020-07-20 journal: Arch Med Res DOI: 10.1016/j.arcmed.2020.07.002 sha: doc_id: 263422 cord_uid: ojdcag0r nan The fact that Parkinson's patients get COVID-19 is probably because their main medication was Levodopa and not amantadine. I would like to point out that amantadine is an antiviral that is able to mitigate the effects of COVID- Phenomenology and outcomes of in-patients with Parkinson's disease during COVID-19 pandemic Online ahead of print Effects of COVID-19 on Parkinson's Disease Clinical Features: A Community-Based Case-Control Study Amantadine as a drug to mitigate the effects of COVID-19 Amantadine Treatment for People with COVID-19 Use of amantadine in a patient with SARS-CoV-2 Online ahead of print
    keywords: amantadine
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        item: #1241 of 7819
          id: cord-263435-rclo9jv4
      author: Oudrhiri, Mohammed Yassaad
       title: Letter: Neurosurgical Patients’ Management During the COVID-19 Pandemic—An Institutional Report From an African Neurosurgical Center
        date: 2020-05-01
       words: 584
      flesch: 41
     summary: Group A patients were operated in the emergency operating room (OR) and group B patients were operated in the mean operating theatre, directly connected to the intensive care unit (ICU). Patients were either admitted directly, if belonging to the Rabat-Salé region (direct admission), or referred from regional hospitals (indirect admission).
    keywords: covid-19; patients
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        item: #1242 of 7819
          id: cord-263457-puf8gjir
      author: Jayarangaiah, Apoorva
       title: COVID-19-Associated Coagulopathy: An Exacerbated Immunothrombosis Response
        date: 2020-07-31
       words: 5559
      flesch: 28
     summary: 2 Additionally, there have been many case reports detailing the association of both venous thromboembolism (VTE) and arterial events in COVID-19 patients. 14 Other aberrancies in coagulopathy, including elevated prothrombin time (PT), partial thromboplastin time, and fibrin-degradation products level, and fibrinogen levels, are also reported in COVID-19 patients with unclear clinical correlations.
    keywords: activation; coagulation; covid-19; endothelial; factor; figure; immunothrombosis; patients; platelet; system; thrombosis
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        item: #1243 of 7819
          id: cord-263474-v5fbahqb
      author: Barsky, Lili L.
       title: Efficacy of clinical evaluations for COVID-19 on the front line
        date: 2020-11-07
       words: 751
      flesch: 35
     summary: In the absence of widespread readily available access to SARS-CoV-2 testing, clinical assessment is and will remain the standard of care for initially determining probability of COVID-19 illness and, in turn, appropriateness for receiving testing-especially in areas where testing availability is limited. This case series from an urban medical center suggests that despite the rapidly evolving body of knowledge around COVID-19 illness and its variable presentations among affected patients, clinical provider assessment of high versus low probability of active infection can be relatively reliable.
    keywords: covid-19; manuscript; testing
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        item: #1244 of 7819
          id: cord-263494-u4tca4es
      author: Jiménez-Rodríguez, Diana
       title: Simulated Video Consultations as a Learning Tool in Undergraduate Nursing: Students’ Perceptions
        date: 2020-08-20
       words: 4288
      flesch: 28
     summary: We conducted a descriptive cross-sectional study using a mixed-method (both quantitative and qualitative data were assessed) to analyze undergraduate nursing students' perceptions of simulated nursing video consultations. The purpose of our study was to explore the undergraduate nursing students’ satisfaction and perceptions about simulated video consultations using the high-fidelity simulation methodology.
    keywords: consultations; covid-19; healthcare; learning; nursing; pandemic; satisfaction; simulation; students; video
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        item: #1245 of 7819
          id: cord-263518-6puccigu
      author: Maarefvand, Masoomeh
       title: Coronavirus Outbreak and Stress in Iranians
        date: 2020-06-20
       words: 4927
      flesch: 44
     summary: Second, this study measured the prevalence of variables rather than incident cases, and we were unable to assess the levels of variables before COVID-19 outbreak in Iran as a control. Coronavirus Map: Tracking the Global Outbreak Estimation of coronavirus disease 2019 (COVID-19) Burden and potential for international dissemination of infection from Iran Public education and electronic awareness of the new Coronavirus (COVID-19): Experiences from Iran Update: Public Health Response to the Coronavirus Disease 2019 outbreak-United States Clinical features of patients infected with 2019 novel coronavirus in Wuhan Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: A web-based cross-sectional survey Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (COVID-19) epidemic among the general population in China Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed Recommended psychological crisis intervention response to the 2019 novel coronavirus pneumonia outbreak in China: A model of West China Hospital.
    keywords: covid-19; groups; health; information; outbreak; people; risk; social; stress; study
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        item: #1246 of 7819
          id: cord-263521-kv3l41qz
      author: Haigh, Kathryn
       title: Hyperinflammation with Covid-19: the key to patient deterioration?()()
        date: 2020-05-24
       words: 886
      flesch: 48
     summary: The potential risk of cytokine storm in patients with coronavirus disease 2019 (Covid-19) has been described(1); we write to share our experience treating a 17-year-old male with haemophagocytic lymphohistiocytosis (HLH) secondary to Covid-19 infection. Considering Russell and colleagues’(3) comments about potential harm of corticosteroid use in patients with Covid-19 infection, the patient was commenced on treatment with the selective IL-1 receptor antagonist drug, Anakinra, and a two day course of intravenous immunoglobulin.
    keywords: covid-19; patient; treatment
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        item: #1247 of 7819
          id: cord-263530-t9ryky6f
      author: Kamal, Yasmine Mohamed
       title: Cerebrospinal fluid confirmed COVID-19-associated encephalitis treated successfully
        date: 2020-09-16
       words: 2492
      flesch: 41
     summary: ► A red flag of the possibility of COVID-19 encephalitis should be raised whenever patients present with abnormal behaviour, acute psychosis, confusion state or drowsiness. Analysis of clinical outcomes in pediatric bacterial meningitis focusing on patients without cerebrospinal fluid pleocytosis Normocellular CSF in herpes simplex encephalitis COVID-19-associated meningoencephalitis complicated with intracranial hemorrhage: a case report We would like to thank Dr Raheel Ahmed for his assistance in direct patient care, as well as Dr Maria Khan, for the final review of the article.
    keywords: brain; covid-19; csf; encephalitis; patient; symptoms
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        item: #1248 of 7819
          id: cord-263544-6ueqx53v
      author: Mauri, Eleonora
       title: Estimating the impact of COVID-19 pandemic on services provided by Italian Neuromuscular Centers: an Italian Association of Myology survey of the acute phase
        date: 2020-06-01
       words: 3349
      flesch: 34
     summary: Surveys, at-distance meetings and virtual platforms will likely be valuable tools to help addressing the future concerns and challenges of NMD centers, aiming at maintaining the best standards of care for NMD patients in these difficult times. AIM associates developed a survey to quantify the extent of changes experienced by NMD centers and patients during these months, and to outline the most effective solutions undertaken, with the ultimate goal of improving NMD patients' care.
    keywords: care; centers; covid-19; hospital; italy; pandemic; patients; services; visits
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        item: #1249 of 7819
          id: cord-263552-6qhb02l2
      author: Chokroverty, Sudhansu
       title: The Many Faces and Fangs of COVID-19: An Editorial
        date: 2020-06-05
       words: 821
      flesch: 48
     summary: Neurological manifestations of hospitalized patients with 224 coronavirus disease-2019 in The neuroinvasive potential of SARS-COV2 may be at least 227 partially responsible for the respiratory failure of COVID-19 patients. Perspective Defining the epidemiology of COVID-19-Studies 183 Public health intervention for COVID-19: Emerging evidence 185 and implications for an evolving public health crisis Association of public health interventions with the 187 epidemiology of the COVID-19 outbreak in Wuhan, China A novel coronavirus from patients with pneumonia in 189 Clinical features of patients infected with 2019 novel 191 coronavirus in Wuhan, China Epidemiological and clinical characteristics of 99 cases 193 of 2019 Novel Coronavirus pneumonia in Wuhan, China: a descriptive study First case of 2019 Novel Coronavirus in the 196 United States First 12 patients with coronavirus disease 2019 198 (COVID-19) in the United States COVID-19 in critically ill patients in the 200 Seattle region-case series The COVID-19 pandemic in the US.
    keywords: coronavirus; covid-19; patients
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        item: #1250 of 7819
          id: cord-263568-ea3k2i69
      author: Price, Elizabeth
       title: Could the severity of COVID-19 be increased by low gastric acidity?
        date: 2020-07-22
       words: 766
      flesch: 51
     summary: As well as protection related to immunological factors and possible differences in the ACE2 receptor concentrations in their lungs, children (other than infants) generally have good levels of gastric acid. To determine whether gastric acid gives some protection from COVID-19, the amount of antacids and acid-reducing drugs used by patients with severe infections could be compared with the amount used by patients with mild or no disease.
    keywords: covid-19; gastric
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        item: #1251 of 7819
          id: cord-263569-x06dked1
      author: Bobenchik, April M.
       title: Testing the asymptomatic pre-surgical population for SARS CoV-2
        date: 2020-08-26
       words: 1273
      flesch: 41
     summary: For the present time, given the greater morbidity of Covid-19 positive surgical patients, screening will continue to include PCR testing until outcome data determine otherwise. Following the initial 11 weeks, the medical center policy changed and outpatient surgical patients were screened with a questionnaire and temperature recording.
    keywords: covid-19; patients; pcr; testing
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        item: #1252 of 7819
          id: cord-263572-h7ya60k5
      author: Taboada, Manuel
       title: Supine versus Prone Positioning in COVID-19 Pneumonia: Comment
        date: 2020-08-17
       words: 362
      flesch: 33
     summary: Prone positioning in severe acute respiratory distress syndrome Efficacy of prone position in acute respiratory distress syndrome patients: A pathophysiology-based review Use of prone positioning in nonintubated patients with COVID-19 and hypoxemic acute respiratory failure The authors declare no competing interests. Here, we present an image ( fig. 1 ) from a computed tomography performed in a 71-yr-old woman with ARDS from COVID-19 in both supine and prone positioning during awake spontaneous ventilation.
    keywords: lung; positioning
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        item: #1253 of 7819
          id: cord-263613-gh9zm05u
      author: Yu, Jingjing
       title: Impact of citywide COVID‐19 testing on people’s behaviour in seeking for dental services in Wuhan
        date: 2020-08-16
       words: 1211
      flesch: 47
     summary: key: cord-263613-gh9zm05u authors: Yu, Jingjing; Hua, Fang; Qin, Danchen; Zhao, Dan; Li, Zhiyong title: Impact of citywide COVID‐19 testing on people’s behaviour in seeking for dental services in Wuhan date: 2020-08-16 journal: Oral Dis DOI: 10.1111/odi.13613 sha: doc_id: 263613 cord_uid: gh9zm05u nan . A retrospective analysis was conducted on patient attendance at WHUSS before and after citywide COVID-19 testing, including the headquarter and 14 satellite clinics of the hospital located in Wuhan.
    keywords: citywide; covid-19; testing
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        item: #1254 of 7819
          id: cord-263625-gqzly8xw
      author: Dighe, Amy
       title: Response to COVID-19 in South Korea and implications for lifting stringent interventions
        date: 2020-10-09
       words: 6158
      flesch: 50
     summary: As case numbers decreased, the average number of cases per test decreased again until the mid-May increase in cases, which resulted in another increase in the average number of cases per test. key: cord-263625-gqzly8xw authors: Dighe, Amy; Cattarino, Lorenzo; Cuomo-Dannenburg, Gina; Skarp, Janetta; Imai, Natsuko; Bhatia, Sangeeta; Gaythorpe, Katy A. M.; Ainslie, Kylie E. C.; Baguelin, Marc; Bhatt, Samir; Boonyasiri, Adhiratha; Brazeau, Nicholas F.; Cooper, Laura V.; Coupland, Helen; Cucunuba, Zulma; Dorigatti, Ilaria; Eales, Oliver D.; van Elsland, Sabine L.; FitzJohn, Richard G.; Green, William D.; Haw, David J.; Hinsley, Wes; Knock, Edward; Laydon, Daniel J.; Mellan, Thomas; Mishra, Swapnil; Nedjati-Gilani, Gemma; Nouvellet, Pierre; Pons-Salort, Margarita; Thompson, Hayley A.; Unwin, H. Juliette T.; Verity, Robert; Vollmer, Michaela A. C.; Walters, Caroline E.; Watson, Oliver J.; Whittaker, Charles; Whittles, Lilith K.; Ghani, Azra C.; Donnelly, Christl A.; Ferguson, Neil M.; Riley, Steven title: Response to COVID-19 in South Korea and implications for lifting stringent interventions date: 2020-10-09 journal: BMC Med DOI: 10.1186/s12916-020-01791-8 sha: doc_id: 263625 cord_uid: gqzly8xw BACKGROUND: After experiencing a sharp growth in COVID-19 cases early in the pandemic, South Korea rapidly controlled transmission while implementing less stringent national social distancing measures than countries in Europe and the USA.
    keywords: cases; centers; control; covid-19; disease; korea; number; prevention; republic; south; south korea; testing; updates
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        item: #1255 of 7819
          id: cord-263627-8ufjh70o
      author: Liang, Li-Lin
       title: Covid-19 mortality is negatively associated with test number and government effectiveness
        date: 2020-07-24
       words: 2749
      flesch: 41
     summary: Simple linear regressions were first applied to investigate the correlation between Covid-19 mortality rate and test number, because the number of COVID-19 testing is more controllable by government than other predictors in our model. As robustness checks, we included variables for GDP per capita, health expenditures and primary school enrolment rate in multiple regressions for Covid-19 mortality rate.
    keywords: covid-19; mortality; number; rate
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        item: #1256 of 7819
          id: cord-263628-ac9gld5l
      author: Sivapalan, Pradeesh
       title: Proactive prophylaxis with azithromycin and hydroxychloroquine in hospitalized patients with COVID-19 (ProPAC-COVID): a statistical analysis plan
        date: 2020-10-20
       words: 3492
      flesch: 46
     summary: Data is analyzed using intention-to-treat (ITT) principles, and main analyses will also be subject to modified ITT analysis and per protocol analysis. Data will be analyzed using intention-to-treat (ITT) principles and main analyses will also be subject to modified ITT analysis (started but not completed the study) and per protocol analysis (completed all interventions).
    keywords: analysis; data; days; oxygen; patients; study; test; treatment; trial
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        item: #1257 of 7819
          id: cord-263631-xna0qtpu
      author: Geng, Jianping
       title: A Silent Infection Pandemic of COVID-19: Epidemiological Investigation and Hypothetical Models
        date: 2020-07-05
       words: 2502
      flesch: 52
     summary: e woman was isolated for treatment and diagnosed as COVID-19 infection on January 26. He was diagnosed as a suspected case of pneumonia with COVID-19 infection by an expert group consultation.
    keywords: china; covid-19; epidemic; infection; rate
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        item: #1258 of 7819
          id: cord-263647-svvvwiqs
      author: Han, Jimin
       title: Sharing Our Experience of Operating an Endoscopy Unit in the Midst of a COVID-19 Outbreak
        date: 2020-03-30
       words: 1442
      flesch: 50
     summary: Safety measures to protect healthcare personnel are therefore always needed in outpatient clinics given that the personnel can incidentally be exposed to COVID-19 patients. As of March 21, 2020, there has been no confirmed case of COVID-19 infection among the patients who underwent ERCP.
    keywords: covid-19; endoscopy; personnel; unit
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        item: #1259 of 7819
          id: cord-263664-isgcm4lj
      author: Lee, Justin
       title: Male Balding is a Major Risk Factor for Severe COVID-19.
        date: 2020-07-22
       words: 341
      flesch: 46
     summary: Descriptive frequencies for COVID-19 results, balding patterns, age, and BMI are reported in Our study compared a large sample of hospitalized COVID-19 positive patients to a control group of hospitalized COVID-19 negative patients and thus builds upon and supports the observations of Wambier 1 and coauthors. Androgenetic Alopecia Present in the Majority of Hospitalized COVID-19 Patients -the Gabrin sign A preliminary observation: Male pattern hair loss among hospitalized COVID-19 patients in Spain -A potential clue to the role of androgens in COVID-19 severity Male pattern baldness: classification and incidence Resource 100423 Screenshot from touchscreen questionnaire used to capture field 2395.
    keywords: covid-19
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        item: #1260 of 7819
          id: cord-263669-d4r4t6ls
      author: Wang, Zhichao
       title: Our Experiences with Plastic and Reconstructive Surgery Procedures during Coronavirus Disease 2019 Pandemic
        date: 2020-05-13
       words: 2478
      flesch: 42
     summary: By direct communication with PRS healthcare professionals with visual interactions, most patients felt satisfied with the additional service by doctors. The close proximity between PRS healthcare professionals and patients puts PRS healthcare professionals at high risk of infection, and the risk is even higher in those who operate in craniofacial regions.
    keywords: cases; covid-19; infection; pandemic; patients; prs
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        item: #1261 of 7819
          id: cord-263670-irhdf4o2
      author: Fried, Jacob
       title: Nasal endoscopy protocols in the era of COVID-19
        date: 2020-05-14
       words: 461
      flesch: 46
     summary: key: cord-263670-irhdf4o2 authors: Fried, Jacob; Imam, Sarah A.; Lee, Joshua A.; Nguyen, Shaun A. title: Nasal endoscopy protocols in the era of COVID-19 date: 2020-05-14 journal: World J Otorhinolaryngol Head Neck Surg DOI: 10.1016/j.wjorl.2020.04.007 sha: doc_id: 263670 cord_uid: irhdf4o2 nan COVID-19, the respiratory illness caused by the novel SARS-CoV-2 virus has rapidly 14 emerged as a serious global health concern.
    keywords: covid-19; nasopharyngoscopy
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        item: #1262 of 7819
          id: cord-263674-kngz6j9q
      author: Chen, Xing
       title: Laboratory abnormalities and risk factors associated with in‐hospital death in patients with severe COVID‐19
        date: 2020-07-12
       words: 2379
      flesch: 44
     summary: In this retrospective cohort study, we reported the risk factors associated with in-hospital death and main laboratory abnormalities in COVID-19 severe patients. This message might reflect the mortality is high among COVID-19 severe patients in the stage of the outbreak, meaning that clear out the risk factors of death is crucial to control the rising number of deaths.
    keywords: covid-19; death; hospital; patients; risk; study
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        item: #1263 of 7819
          id: cord-263703-5csf9z6s
      author: Fernandez Villalobos, N. V.
       title: Quantification of the association between predisposing health conditions, demographic, and behavioural factors with hospitalisation, intensive care unit admission, and death from COVID-19: a systematic review and meta-analysis
        date: 2020-08-01
       words: 5761
      flesch: 43
     summary: We included reports if: a) patients had COVID-19, either confirmed microbiologically or clinically (population); b) information on COVID-19 outcome was reported as either death (hospital or after a defined follow-up time), ICU admission (both ICU and intermediate care), hospitalisation or aggravation of disease (clinical description) (outcome); and c) at least one comorbidity, risk factor or behavioural factor was described and if number of patients with/without outcome was reported according to the respective factor (exposure and comparison). Prog Cardiovasc Dis Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia -A systematic review, meta-analysis, and meta-regression Prevalence and severity of corona virus disease 2019 (COVID-19): A systematic review and meta-analysis Arterial hypertension and risk of death in patients with COVID-19 infection: systematic review and metaanalysis Cerebrovascular disease is associated with an increased disease severity in patients with Coronavirus Disease 2019 (COVID-19): A pooled analysis of published literature Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement ROBINS-I: a tool for assessing risk of bias in non-randomized studies of interventions Clinical Features and Short-term Outcomes of 102 Patients with Corona Virus Disease Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Low-density lipoprotein is a potential predictor of poor prognosis in patients with coronavirus disease 2019 Clinical and Transmission Characteristics of Covid-19 -A Retrospective Study of 25 Cases From a Single Thoracic Surgery Department Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN:
    keywords: age; comorbidities; covid-19; disease; meta; patients; preprint; risk; studies
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        item: #1264 of 7819
          id: cord-263716-ywsm11aw
      author: Zhou, Yifan
       title: Clinical time course of COVID-19, its neurological manifestation and some thoughts on its management
        date: 2020-05-04
       words: 1798
      flesch: 56
     summary: In severe patients, 5 (6%) had strokes, 13 (15%) had cognitive impairment and 17 (19%) had musculoskeletal damage. 14 15 In severe patients, retaining CO 2 is a challenging problem.
    keywords: covid-19; infection; patients; phase; symptoms
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        item: #1265 of 7819
          id: cord-263736-n4mjdlgx
      author: Pinto, A. C. P. N.
       title: Pharmacological interventions for COVID-19: Protocol for a Rapid Living Systematic Review with network meta-analysis
        date: 2020-05-06
       words: 2258
      flesch: 46
     summary: Coronavirus Disease (COVID-19) Pandemic Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement The PRISMA extension statement for reporting of systematic reviews incorporating network meta-analyses of health care interventions: checklist and explanations Cochrane Rapid Reviews Interim Guidance from the Cochrane Rapid Reviews Methods Group 2020 Optimal search strategies for retrieving scientifically strong studies of treatment from Medline: analytical survey Rayyan -a web and mobile app for systematic review Cochrane Handbook for Systematic Reviews of Interventions Grading quality of evidence and strength of recommendations Grade's software for summary of findings tables, health technology assessment and guidelines We will perform the critical appraisal of included studies with the Risk of Bias tool and the certainty of evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation (GRADE).
    keywords: covid-19; interventions; license; preprint; review; studies
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        item: #1266 of 7819
          id: cord-263738-8g5ujfaf
      author: Qian, Jing-Yi
       title: Acute Kidney Injury in the 2019 Novel Coronavirus Disease
        date: 2020-06-18
       words: 3517
      flesch: 46
     summary: These results provide direct evidence that the SARS-CoV-2 virus can directly infect the renal tubular epithelium and podocytes, which may induce AKI in COVID-19 patients [17] . Moreover, a study of 52 critically ill patients showed that lymphocytopenia occurred in more than 80% of COVID-19 patients [7] .
    keywords: acute; aki; clinical; coronavirus; covid-19; disease; kidney; patients; sars
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        item: #1267 of 7819
          id: cord-263749-bbhh5xb1
      author: Larenas-Linnemann, Désirée
       title: Enhancing innate immunity against virus in times of COVID-19: trying to untangle facts from fictions
        date: 2020-10-09
       words: 4134
      flesch: 0
     summary: Results For each of these interventions we briefly comment on their definition, possible mechanisms and evidence of clinical efficacy or lack of it, especially focusing on respiratory tract infections, viral infections and eventually a reduced mortality in severe respiratory infections in the intensive care unit. With the use of Pidotimod there is a lower recurrence of respiratory tract infections as compared to conventional treatment and less use of antibiotics We encourage to wait for the results of the ongoing RCT before using BCG vaccination for the prevention of COVID-19 Hetero- The immune stimulation produced by heterologous vaccines enhances the response to other pathogens, different from the one in the vaccine and was associated with reduced all-cause infant mortality (e.g. measles vaccine, BCG).
    keywords: activity; acute; analysis; cells; covid-19; exercise; immunity; infections; review; sleep; tract; vitamin
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        item: #1268 of 7819
          id: cord-263753-p3evgngz
      author: Magoon, Rohan
       title: Dexmedetomidine in COVID-19: probing promises with prudence!
        date: 2020-10-27
       words: 463
      flesch: 22
     summary: A case report Potential therapeutic value of dexmedetomidine in COVID-19 patients admitted to ICU Dexmedetomidine-associated hyperthermia: A series of 9 cases and a review of the literature Dexmedetomidine-Associated Hyperpyrexia in Three Critically Ill Patients With Coronavirus Disease Sedation, Analgesia, and Paralysis in COVID-19 Patients in the Setting of Drug Shortages COVID-19: ICU delirium management during SARS-CoV-2 pandemic Incidence of dexmedetomidine withdrawal in adult critically Ill patients: a pilot study Sedation for critically ill patients with COVID-19: Which specificities? However, withdrawal can be prevented with the meticulous use of drug or mitigated with clonidine [5] . (iii) In addition, once on invasive mechanical ventilation, a precision approach to sedation in COVID-19 patients, as epitomized by Payen et al, appears to be prudent centralising the focus on inter-individual variability and synchronizing the level of ventilator support to the subsequent target of sedation, thereby directing the subsequent choice of sedative agents, including DEX [8, 9] .
    keywords: covid-19; dexmedetomidine
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        item: #1269 of 7819
          id: cord-263754-iv21q46l
      author: Cuadrado, Antonio
       title: Can activation of NRF2 be a strategy against COVID-19?
        date: 2020-07-14
       words: 1507
      flesch: 13
     summary: Ecancermedicalscience 14 Risks Related to the Use of Non-Steroidal Anti-Inflammatory Drugs in Community-Acquired Pneumonia in Adult and Pediatric Patients The Invisible Threat of Non-steroidal Anti-inflammatory Drugs for Kidneys Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials Risk of stroke associated with use of nonsteroidal antiinflammatory drugs during acute respiratory infection episode SARS-CoV-2 infection: The role of cytokines in COVID-19 disease Antioxidants in Translational Medicine Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: the indirect antioxidant effects of sulforaphane Direct and indirect antioxidant properties of inducers of cytoprotective proteins Metabolism and disposition of acetaminophen: recent advances in relation to hepatotoxicity and diagnosis Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts Isoquinoline Kelch-like ECH-Associated Protein 1-Nuclear Factor (Erythroid-Derived 2)-like 2 (KEAP1-NRF2) Inhibitors with High Metabolic Stability An open-source drug discovery platform enables ultralarge virtual screens cGAS and STING: The isothiocyanate sulforaphane (SFN), originally isolated from broccoli, a cruciferous vegetable, as an inducer of the classical NRF2 target, NAD(P)H:quinone oxidoreductase 1 (NQO1) [76] , is the most potent naturally occurring NRF2 activator, with well-documented antioxidant and anti-inflammatory effects [77] .
    keywords: activation; covid-19; factor; lung; nrf2; sulforaphane
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        item: #1270 of 7819
          id: cord-263763-a8wgvgz2
      author: Çelik, Ersin
       title: Treatment Approach to Coronavirus Disease (COVID-19) Seen Early After Open Heart Surgery. Case Report
        date: 2020-07-02
       words: 1540
      flesch: 45
     summary: We aimed to present our approach to high probability COVID-19 pneumonia which developed on early postoperative period in our patient after coronary artery bypass grafting (CABG) operation, which was not reported in the literature before. We should assume and keep in mind that there are also pandemic and asymptomatic carriers, especially in elderly patients who undergo open heart surgery with many additional risk factors.
    keywords: covid-19; patient; pcr
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        item: #1271 of 7819
          id: cord-263801-01goni72
      author: Sobral, Marcos Felipe Falcão
       title: Association between climate variables and global transmission oF SARS-CoV-2
        date: 2020-08-10
       words: 2958
      flesch: 40
     summary: • Negative association between country average temperature and COVID-19 infections. No association between deaths and country temperature or precipitation.
    keywords: cov-2; covid-19; sars; temperature
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        item: #1272 of 7819
          id: cord-263840-1t4ykc01
      author: Altay, Ozlem
       title: Current status of COVID-19 therapies and drug repositioning applications
        date: 2020-06-20
       words: 2103
      flesch: 22
     summary: No specific 124 therapies for COVID-19 is approved by U.S. Food and Drug Administration (FDA) so far but many 125 previously approved drugs, as an efficient approach to drug discovery named drug repurposing, is being 126 tested on COVID-19. In-silico drug repurposing methodologies have accelerated the studies in drug discovery through the use 250 of data mining approaches, bioinformatics techniques, and predictive models for determining the efficacy 251 and safety of the drugs.
    keywords: coronavirus; covid-19; discovery; drug; patients; repurposing; sars; treatment
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        item: #1273 of 7819
          id: cord-263861-7a076c90
      author: Hossien Mehrsafar, Amir
       title: Addressing potential impact of COVID-19 pandemic on physical and mental health of elite athletes
        date: 2020-05-06
       words: 468
      flesch: 37
     summary: Brain, behavior, and immunity Considerations for sports federations/sports event organizers 108 when planning mass gatherings in the context of COVID-19: interim guidance Mental 114 health in elite athletes: International Olympic Committee consensus statement Sport psychology 117 services to high performance athletes during COVID-19 The immunological case for staying active during the COVID-19 120 pandemic. While teams and coaches might try to find ways to save elite athletes first, lower-level 83 athletes are prone to more challenges under these conditions.
    keywords: athletes; covid-19
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        item: #1274 of 7819
          id: cord-263882-s5oxr6es
      author: Najar Nobar, Niloufar
       title: Patients with specific skin disorders who are affected by COVID‐19: what do experiences say about management strategies? : A systematic review
        date: 2020-06-18
       words: 2546
      flesch: 33
     summary: Cutaneous manifestations in COVID-19: a first perspective Cutaneous manifestations in COVID-19: a first perspective by Recalcati S Clinical and Histopathological study of skin dermatoses in patients affected by COVID-19 infection in the Northern part of Italy Cutaneous manifestations of COVID-19: Report of three cases and a review of literature Dermatologic findings in two patients with COVID-19 Cutaneous manifestation of COVID-19 in images: A case report Alert for non-respiratory symptoms of Coronavirus Disease 2019 (COVID-19) patients in epidemic period: A case report of familial cluster with three asymptomatic COVID-19 patients Occupational skin disease among health care workers during the coronavirus (COVID-19) epidemic A distinctive skin rash associated with Coronavirus Disease A Case of COVID-19 Pneumonia in a Young Male with Full Body Rash as a Presenting Symptom Morbilliform exanthem associated with COVID-19 Rash as a Clinical Manifestation of COVID 19 Photographs of a Patient SARS-CoV-2 infection presenting as a febrile rash Urticarial eruption in COVID-19 infection Urticarial exanthem as early diagnostic clue for COVID-19 infection A case of COVID-19 presenting in clinical picture resembling chilblains disease. No evidence of increased risk for COVID-19 infection in patients treated with Dupilumab for atopic dermatitis in a high-epidemic area Systemic Isotretinoin Therapy In The Era Of COVID19 Evolution of COVID-19 infection in 4 psoriatic patients treated with biological drugs Occurrence of SARS-CoV-2 during mycophenolate mofetil treatment for pemphigus Mucous membrane pemphigoid and COVID-19 treated with highdose intravenous immunoglobulins: a case-report COVID-19 pulmonary infection in erythrodermic psoriatic patient with oligodendroglioma: safety and compatibility of apremilast with critical intensive care management A challenging case of psoriasis flare-up after COVID-19 infection COVID-19 in an elderly patient treated with secukinumab Improvement of SARS-CoV2 symptoms following Guselkumab injection in a psoriatic patient SARS-CoV-2 infection in a psoriatic patient treated with IL-23 inhibitor Systemic Immunobiological, Immunosuppressant and Oncologic Agents for the Treatment of Dermatologic Diseases during the SARS-Cov-2 (COVID19) Pandemic Emergency: a Quick Review for a Quick Consultation Evaluating the role of stress in skin disease.
    keywords: covid-19; disease; infection; patients; skin; treatment
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        item: #1275 of 7819
          id: cord-263883-7ba0huwy
      author: Ansarin, Khalil
       title: Effect of bromhexine on clinical outcomes and mortality in COVID-19 patients: A randomized clinical trial
        date: 2020-07-19
       words: 3121
      flesch: 47
     summary: The data analysis of this clinical trial also showed that cardinal respiratory symptoms (cough, lassitude, and dyspnea) in patients with COVID-19 disease who received bromhexine treatment was remarkably less than the standard group. Patients with COVID-19 disease release high amounts of LDH into circulation due to cytokine release and lung damage.
    keywords: arm; bromhexine; covid-19; disease; group; patients; standard; treatment
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        item: #1276 of 7819
          id: cord-263901-hmqq9w1a
      author: Yurdaisik, Isil
       title: Effectiveness of Computed Tomography in the Diagnosis of Novel Coronavirus-2019
        date: 2020-05-15
       words: 3044
      flesch: 48
     summary: A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Time course of lung changes on chest CT during recovery from 2019 novel coronavirus Emerging coronavirus 2019-nCoV pneumonia Severe acute respiratory disease in a Huanan seafood market worker: Images of an early casualty COVID-19): What is the role of radiologists? Liu: Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study CT imaging features of 2019 novel coronavirus (2019-nCoV). In a study, fever was reported as 83%, cough as 82%, and shortness of breath as 31% of COVID-19 patients [12] .
    keywords: chest; coronavirus; covid-19; diagnosis; disease; patients
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        item: #1277 of 7819
          id: cord-263908-4ti8l2ea
      author: Gupta, Ritesh
       title: Diabetes and COVID-19: evidence, current status and unanswered research questions
        date: 2020-05-13
       words: 3695
      flesch: 41
     summary: Prevalence ofcomorbidities in the novel Wuhan coronavirus (COVID-19) infection: asystematicreview and meta-analysis Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Effects of hypertension, diabetes and coronary heart disease on COVID-19 diseases severity: a systematic review and meta-analysis Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Glycemic characteristics and clinical outcomes of COVID-19 patients hospitalized in the United States Glycemic control and risk of infections among people with type 1 or type 2 diabetes in a large primary care cohort study Type 2 diabetes mellitus and altered immune system leading to Diabetes and COVID-19: evidence, current status and unanswered research questions susceptibility to pathogens, especially mycobacterium tuberculosis T-cell activation and cardiovascular risk in adults with type 2 diabetes mellitus: A systematic review and meta-analysis Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics Obesity and the risk and outcome of infection Elevated Plasmin(ogen) as a common risk factor for COVID-19 susceptibility Diabetes is a risk factor for the progression and prognosis of COVID-19 Plasma levels of the proprotein convertase furinandincidence of diabetes and mortality There have been a lot of literature and debate whether these drugs could benefit or harm patients having COVID-19 infection.
    keywords: ace2; angiotensin; covid-19; diabetes; disease; infection; inhibitors; patients; risk
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        item: #1278 of 7819
          id: cord-263936-8yud5o6c
      author: Wang, Gary X.
       title: Opportunities for Radiology Trainee Education Amid the COVID-19 Pandemic: Lessons from an Academic Breast Imaging Program
        date: 2020-10-03
       words: 2814
      flesch: 29
     summary: While reduced clinical imaging volume and mandates to maintain physical distancing presented new challenges to traditional medical education during this period, new opportunities developed to support our division in providing high-quality training for residents and fellows. While all senior residents had already fulfilled ACGME breast imaging requirements prior to implementation of the virtual curriculum, the schedule for the next academic year (2020-2021) was constructed to ensure remaining junior residents fulfilled their required 12 weeks of clinical breast imaging rotations prior to graduation.
    keywords: attending; breast; fellows; imaging; pandemic; site; support
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        item: #1279 of 7819
          id: cord-263940-dzb5idx2
      author: Martinez-Lopez, J.
       title: Multiple Myeloma and SARS-CoV-2 Infection: Clinical Characteristics and Prognostic Factors of Inpatient Mortality
        date: 2020-06-30
       words: 4573
      flesch: 38
     summary: At hospital admission, MM patients had numerically lower median levels of neutrophils, lymphocytes, and platelets, and numerically higher concentrations of D-dimers and ferritin compared with non-cancer patients ( Table 1) . Mortality was 50% higher in MM patients (34%) vs non-cancer patients (23%).
    keywords: covid-19; license; medrxiv; mortality; non; patients; preprint
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        item: #1280 of 7819
          id: cord-263945-yli5suxb
      author: Iancu, Gabriela Mariana
       title: Viral exanthema as manifestation of SARS-CoV-2 infection: A case report
        date: 2020-08-28
       words: 2220
      flesch: 41
     summary: A meta-analysis of 19 studies published by Sachdeva et al, showed that cutaneous manifestations can precede respiratory ones by 3 days (12.50% of cases) or can appear after 13 days (69.40%) from the onset of respiratory manifestations in SARS-CoV-2. [2] All these are nonspecific and can be encountered in other viral respiratory infections but the development of pneumonia (dyspnea and bilateral infiltrates on lung imaging) several days after the onset of symptoms is highly suggestive in the present context.
    keywords: case; days; infection; manifestations; patients; sars
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        item: #1281 of 7819
          id: cord-263968-v9sncm4l
      author: Ahmed, Anwar E.
       title: Incidence of coronavirus disease (COVID-19) and countries affected by malarial infections
        date: 2020-04-22
       words: 664
      flesch: 43
     summary: As of March 22, 2020, results indicate world regions that are malaria free or recorded limited malarial infections reported a large number of COVID-19 cases ( The Poisson regression is used to assess whether the malarial incidence rate (per 1000 population at risk) is a predictor for increased cases of COVID-19. The study utilized publicly available data on COVID-19 cases by countries reporting [2] .
    keywords: covid-19; incidence
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        item: #1282 of 7819
          id: cord-263993-gbbkcwo7
      author: Salazar, Leonardo Alberto
       title: CONSENSO ECMO COLOMBIANO PARA PACIENTE CON FALLA RESPIRATORIA GRAVE ASOCIADA A COVID-19
        date: 2020-10-06
       words: 6721
      flesch: 33
     summary: Esta valoración se realiza utilizando la escala RESP y la evaluación de la fragilidad. Adicionalmente, existen tres escenarios para definir la prioridad para que un paciente sea considerado para la terapia, uno de ellos es la escala de fragilidad clínica, la cual ya ha sido evaluada previamente para pacientes en cuidados agudos y el segundo punto es la disponibilidad de camas de UCI y finalmente la disponibilidad de atención en los centros de ECMO durante la evolución de la pandemia actual.
    keywords: acuerdo; aguda; colombia; como; con; con el; con la; confirmación; consenso; covid-19; de ecmo; de la; de los; del; dificultad; ecmo; extracorporeal; grave; grupo; la terapia; las; los; oxygenation; pacientes; pacientes con; para; por; que; refractaria; respiratoria; sospecha; síndrome; terapia; una; ventilación
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        item: #1283 of 7819
          id: cord-264037-43yr6qon
      author: Kang, Yun-Jung
       title: Lessons Learned From Cases of COVID-19 Infection in South Korea
        date: 2020-05-07
       words: 2857
      flesch: 54
     summary: On March 6, 2020, the number of confirmed cases was 6284, with 42 dead. [28] [29] [30] Patients, after feeling their symptoms or finding out that they had contact with confirmed cases, confined themselves to their homes and shunned crowded places to prevent infecting others.
    keywords: cases; church; covid-19; infection; korea; masks; people
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        item: #1284 of 7819
          id: cord-264051-ps0x2es1
      author: Li, Wei
       title: Human Identical Sequences of SARS-CoV-2 Promote Clinical Progression of COVID-19 by Upregulating Hyaluronan via NamiRNA-Enhancer Network
        date: 2020-11-05
       words: 8954
      flesch: 43
     summary: Such discrepancies may be owing to the binding of hyaluronan and its ligand CD44, which can induce the death of activated T cells (McKallip et al., 2002) . Noteworthily, as the antiviral immunity guardian, T cells are reduced significantly in COVID-19 patients (Diao et al., 2020) , which is negatively correlated with survival rates.
    keywords: cov-2; covid-19; et al; expression; g t; gene; hek293 t; host; human; hyaluronan; level; patients; rna; sars; t c; t cells; t t; virus
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        item: #1285 of 7819
          id: cord-264052-uph136sn
      author: Wilson, Mitchell P
       title: Coronavirus disease (COVID-19) in neurology and neurosurgery: A scoping review of the early literature
        date: 2020-04-23
       words: 2115
      flesch: 31
     summary: As the number of COVID-19 cases continues to rise dramatically across the world, we anticipate that the literature will also continue to evolve. Although uncommon, background cerebrovascular disease may be a risk factor for poor outcome in COVID-19 patients (5) .
    keywords: cases; coronavirus; covid-19; disease; sars
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        item: #1286 of 7819
          id: cord-264073-yhztrscf
      author: Betonico, Gustavo Navarro
       title: Challenges in COVID‐19 medical response: a nephrology perspective
        date: 2020-06-20
       words: 1706
      flesch: 41
     summary: In general, dialysis indications in COVID-19 patients follow the same recommendations as in other acute kidney injuries. All this volume-restricted protocols in COVID-19 patients must keep ICU staff This article is protected by copyright.
    keywords: covid-19; dialysis; disease; kidney; patients; symptoms
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        item: #1287 of 7819
          id: cord-264080-fbp9rr5z
      author: Coppola, Alessandro
       title: An Invited Commentary on: Optimizing response in surgical systems during and after COVID-19 pandemic: lessons from China and the UK – Perspective. Zheng Liu (IJS-D-20-00464)
        date: 2020-05-19
       words: 760
      flesch: 40
     summary: key: cord-264080-fbp9rr5z authors: Coppola, Alessandro; Coppola, Roberto title: An Invited Commentary on: Optimizing response in surgical systems during and after COVID-19 pandemic: lessons from China and the UK – Perspective. Zheng Liu (IJS-D-20-00464) date: 2020-05-19 journal: Int J Surg DOI: 10.1016/j.ijsu.2020.05.048 sha: doc_id: 264080 cord_uid: fbp9rr5z nan Optimizing response in surgical systems during and after COVID-19 pandemic: lessons from China and the UK -Perspective.
    keywords: covid-19; pandemic; patients
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        item: #1288 of 7819
          id: cord-264113-dh74pv64
      author: Garcia Garcia de Alcaniz, J.
       title: Groundbreaking predictions about COVID-19 pandemic duration, number of infected and dead: A novel mathematical approach never used in epidemiology
        date: 2020-08-06
       words: 2811
      flesch: 39
     summary: key: cord-264113-dh74pv64 authors: Garcia Garcia de Alcaniz, J.; Lopez-Rodas, V.; Costas, E. title: Groundbreaking predictions about COVID-19 pandemic duration, number of infected and dead: A novel mathematical approach never used in epidemiology date: 2020-08-06 journal: nan DOI: 10.1101/2020.08.05.20168781 sha: doc_id: 264113 cord_uid: dh74pv64 Hundreds of predictions about the duration of the pandemic and the number of infected and dead have been carried out using traditional epidemiological tools (i.e. SIR, SIRD models, etc.) or new procedures of big-data analysis. Early transmission dynamics in Wuhan, China, of novel coronavirusinfected pneumonia Impact of meteorological factors on the COVID-19 transmission: A multi-city study in China Kidney impairment is associated with in-hospital death of COVID-19 patients The impact of 2019 novel coronavirus on heart injury: A systemic review and Meta-analysis Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia -A systematic review, meta-analysis, and meta-regression: Diabetes and COVID-19 Comorbidity and its impact on 1590 patients with Covid-19 in China: A Nationwide Analysis Myocardial injury is associated with in-hospital mortality of confirmed or suspected COVID-19 in Wuhan, China: A single center retrospective cohort study Clinical progression of patients with COVID-19 in Shanghai Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study Caution on kidney dysfunctions of COVID-19 patients Experimental treatment with favipiravir for COVID-19: an openlabel control study Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China Analysis of myocardial injury in patients with COVID-19 and association between concomitant cardiovascular diseases and severity of COVID-19 Kidney disease is associated with in-hospital death of patients with COVID-19 Modes of Thought Does God play dice Statistical Methods Iowa State College Press Taming the infinite High Temperature and High Humidity Reduce the Transmission of COVID-19 Development of an assessment method for investigating the impact of climate and urban parameters in confirmed cases of COVID-19:
    keywords: covid-19; medrxiv; models; number; pandemic; preprint
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        item: #1289 of 7819
          id: cord-264128-o3p92gx0
      author: Ahmar, Ansari Saleh
       title: Will Covid-19 confirmed cases in the USA reach 3 million? A forecasting approach using SutteARIMA
        date: 2020-09-28
       words: 1145
      flesch: 62
     summary: 264128 cord_uid: o3p92gx0 Objectives Examining about forecasting the number of Covid-19 cases in the US can provide an overview and projection of the development of Covid-19 cases in the US so that policy makers can determine the steps that must be taken. Based on data presented by Worldometer on 20 April 2020, the number of confirmed cases of Covid-19 in United State was 792,759 cases or added 28,123 cases from yesterday (19 April 2020) with 42,514 total deaths and was the first highest country with confirmed cases of covid-19 in the world
    keywords: cases; data; method
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        item: #1290 of 7819
          id: cord-264136-jjtsd4n3
      author: Ferstad, Johannes Opsahl
       title: A model to forecast regional demand for COVID-19 related hospital beds
        date: 2020-03-30
       words: 2763
      flesch: 39
     summary: [2, 3] Its rapid spread in China and Italy quickly overwhelmed available hospital beds. The urgency of the challenge and widespread data sharing have led to the development of numerous models of COVID-19: models designed to share the most recent data on confirmed cases and deaths [16] ; technical models intended for use by epidemiologists [17, 18, 21] ; and models presenting high-level summaries of the potential for COVID-19 associated bed demand to overwhelm hospital capacity [9, 19, 22] .
    keywords: beds; covid-19; hospital; model; number; time
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        item: #1291 of 7819
          id: cord-264143-30h09e1k
      author: Kim, M. S.
       title: Comparative Efficacy and Safety of Pharmacological Managements for Hospitalized COVID-19 Patients: Protocol for Systematic Review and Trade-Off Network Meta-Analysis.
        date: 2020-05-22
       words: 2014
      flesch: 35
     summary: Two authors (MA, WK) will independently assess risk of bias (RoB) in included studies using the Cochrane Collaboration's tool for RoB assessment (3) . https://doi.org/10.1101/2020.05.18.20103697 doi: medRxiv preprint Coronavirus Disease 2019 (COVID-19) is the disease caused by the virus SARS-CoV-2 first discovered in Wuhan, China in 2019.
    keywords: covid-19; disease; license; medrxiv; preprint; studies
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        item: #1292 of 7819
          id: cord-264145-73e61rlq
      author: Belančić, Andrej
       title: Gut microbiome dysbiosis and endotoxemia - Additional pathophysiological explanation for increased COVID-19 severity in obesity
        date: 2020-09-18
       words: 1329
      flesch: 12
     summary: Taking everything into consideration, it is very likely that gut microbiome dysbiosis and endotoxemia represent the additional pathophysiological explanation for increased COVID-19 severity in obesity. Taking everything into consideration, it is very likely that gut microbiome dysbiosis and endotoxemia represent the additional pathophysiological explanation for increased COVID-19 severity in obesity.
    keywords: gut; lps; microbiome; obesity
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        item: #1293 of 7819
          id: cord-264148-qpcvxwti
      author: He, Feng
       title: Coronavirus disease 2019: What we know?
        date: 2020-03-28
       words: 2069
      flesch: 43
     summary: A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection The severe acute respiratory syndrome coronavirus in tears Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: a data-driven analysis in the early phase of the outbreak Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Presumed asymptomatic carrier transmission of COVID-19 Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72314 cases from the Chinese center for disease control and prevention Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical features of patients infected with 2019 novel coronavirus in Wuhan Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19 Time course of lung changes on chest ct during recovery from 2019 novel coronavirus (COVID-19) pneumonia. The analysis of samples from seven SARS-CoV-2 infected patients suggested that SARS-CoV-2 shares 79.5% sequence identity to SARS-CoV. 3 Simplot analysis showed that SARS-CoV-2 share 96.2% overall genome sequence identity to RaTG13, which is a short RdRp region from a bat CoV. 3 Phylogenetic analysis revealed that SARS-CoV-2 falls into the subgenus Sarbecovirus of the genus Betacoronavirus and is distinct from SARS-CoV. 2, 4 The envelope spike (S) protein is important for CoV. 19 The S protein mediates receptor binding and membrane fusion and is crucial for determining host tropism and transmission capacity.
    keywords: coronavirus; cov; covid-19; novel; patients; sars
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        item: #1294 of 7819
          id: cord-264180-0vd3tr9j
      author: Gupta, Anupam K
       title: Is It Safe to Perform Lung Surgery During the Coronavirus Pandemic?
        date: 2020-08-14
       words: 1636
      flesch: 58
     summary: This study was conducted to evaluate whether it is safe to perform lung surgery in the community where there is a rapidly increasing number of coronavirus patients. Conclusion: With adequate precautions, older patients can undergo lung surgery during this pandemic.
    keywords: coronavirus; covid-19; patients; surgery
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        item: #1295 of 7819
          id: cord-264204-4ablrwuo
      author: Guintivano, Jerry
       title: Psychiatric Genomics Research During the COVID-19 Pandemic: A Survey of Psychiatric Genomics Consortium Researchers
        date: 2020-10-08
       words: 4002
      flesch: 37
     summary: (16.2%), offer greater support to early career researchers (e.g. advocate for junior researchers, create support groups for early career researchers) (14.9%), provide support for researchers directly impacted by COVID-19 (e.g. leniency for those who see patients and other caregivers, support career advancement for those directly affected by COVID-19) (10.8%) , provide funding to support researchers (e.g. bridge funding to sustain PGC research especially among junior researchers and those not part of core PGC funding) (10.8%), and provide online training (e.g. statistical genetics and other key topic courses) (8.1%). We modeled our questionnaire after Weissman et al (Weissman et al., 2020) and assessed: (a) the impact of COVID-19 on PGC research now and in the foreseeable future; (b) the level of concern about COVID-19-related disruptions of research and the potential impact of these disruptions on individuals' careers; (c) strategies that respondents thought to be effective in coping with COVID-19-related research disruptions; and (d) respondents' suggestions for how the PGC or the field should respond to help researchers move through and beyond the current crisis.
    keywords: career; covid-19; pgc; research; researchers; respondents; responses
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        item: #1296 of 7819
          id: cord-264206-u9c8rrrv
      author: Pata, Ugur Korkut
       title: How is COVID-19 affecting environmental pollution in US cities? Evidence from asymmetric Fourier causality test
        date: 2020-07-15
       words: 3415
      flesch: 48
     summary: Therefore, Asna-ashary et al. (2020) empirically investigated the pollution-COVID-19 nexus and reported a negative relationship between PM 2.5 emissions and positive shocks in COVID-19 cases in 31 Iranian provinces. In the equation, y t represents the vector containing the variables of COVID-19 cases and deaths, and PM 2.5 emissions, β is the coefficients matrix, t is the trend, T denotes the number of observations, γ 1 and γ 2 are the coefficients of the Fourier approximation that smooth structural shifts are captured, and d max is the maximum integration degree of the series that can be determined by a unit root test.
    keywords: cases; covid-19; deaths; emissions; fourier; shocks; test
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        item: #1297 of 7819
          id: cord-264220-xfptlkuc
      author: Tan, Chaochao
       title: C‐reactive protein correlates with computed tomographic findings and predicts severe COVID‐19 early
        date: 2020-04-25
       words: 1904
      flesch: 49
     summary: patients had close contact with COVID-19 patients, and 4 patients (15%) denied any obvious history of exposure. In conclusion, we found that patients with flu had higher WBC, granulocyte and granulocyte/lymphocyte ratio, compared with COVID-19 patients.
    keywords: covid-19; patients; stage
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        item: #1298 of 7819
          id: cord-264226-9tgnx7du
      author: Caramelo, Francisco
       title: Estimation of risk factors for COVID-19 mortality - preliminary results
        date: 2020-02-25
       words: 2592
      flesch: 50
     summary: https://doi.org/10.1101/2020.02.24.20027268 doi: medRxiv preprint case are expected to be small. China CDC has reported results of a descriptive exploratory analysis of all cases diagnosed until the 11th February 2020, presenting the epidemiologic curves and geo-temporal spread of COVID-19 along with case fatality rate according to some baseline characteristics, such as age, gender and several well-established high prevalence comorbidities.
    keywords: age; gender; license; preprint
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        item: #1299 of 7819
          id: cord-264237-s14pygkh
      author: Wallis, Neil
       title: Implementation of field hospital pharmacy services during the COVID-19 pandemic
        date: 2020-06-15
       words: 2448
      flesch: 44
     summary: It was determined that on-site pharmacy services would be imperative to ensure that FH patients received optimal care. key: cord-264237-s14pygkh authors: Wallis, Neil; Gust, Carmen; Porter, Emily; Gilchrist, Neil; Amaral, Angel title: Implementation of field hospital pharmacy services during the COVID-19 pandemic date: 2020-06-15 journal: Am J Health Syst Pharm DOI: 10.1093/ajhp/zxaa211 sha: doc_id:
    keywords: care; covid-19; hospital; medications; patients; pharmacy; services
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        item: #1300 of 7819
          id: cord-264248-wqkphg2e
      author: Hazem, Y.
       title: Hasty Reduction of COVID-19 Lockdown Measures Leads to the Second Wave of Infection
        date: 2020-05-26
       words: 2266
      flesch: 48
     summary: The results showed an inevitable second wave of COVID-19 infection following loosening the current measures. Hence, it is important to understand the consequences of easing lockdown measures and refreshing the economy.
    keywords: covid-19; infection; measures; preprint
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        item: #1301 of 7819
          id: cord-264260-8p6pvjkn
      author: Peng, Hongbing
       title: A synergistic role of convalescent plasma and mesenchymal stem cells in the treatment of severely ill COVID-19 patients: a clinical case report
        date: 2020-07-16
       words: 3168
      flesch: 44
     summary: Convalescent plasma donors come from COVID-19 patients who meet the criteria for desegregation and discharge. From admission to discharge, the researchers continue to observe and evaluate patients' dynamic changes in clinical symptoms and laboratory results, especially after receiving plasma and stem cell therapy.
    keywords: cells; convalescent; covid-19; mscs; patients; plasma; stem; treatment
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        item: #1302 of 7819
          id: cord-264264-7j3xirfg
      author: TüRsen, Ümit
       title: CORONAVIRUS‐DAYS IN DERMATOLOGY
        date: 2020-04-15
       words: 2147
      flesch: 44
     summary: The following is based on expert opinion, taking into account the known risks of other RNA viruses. Soap works better than alcohol and disinfectants at destroying the structure of viruses.
    keywords: alcohol; covid-19; human; skin; soap; virus; viruses
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        item: #1303 of 7819
          id: cord-264266-6xvj9zey
      author: Chakrabarti, Sankha Shubhra
       title: COVID-19 in India: Are Biological and Environmental Factors Helping to Stem the Incidence and Severity?
        date: 2020-05-09
       words: 3852
      flesch: 44
     summary: However, this again raises queries on why Iran having a dry desert climate (type B) bore the brunt of COVID-19 cases [3] . The world's second-most populous country lies around the 40 th rank among nations for the number of diagnosed COVID-19 cases (www.worldometers.info/coronavirus/).
    keywords: cases; cov-2; covid-19; cross; immunity; india; patients; sars; viruses
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        item: #1304 of 7819
          id: cord-264277-mh6og6pq
      author: Atallah, Juliana
       title: The importance of imaging – Perspectives from redeployment
        date: 2020-10-13
       words: 2097
      flesch: 36
     summary: As the coronavirus disease 2019 (COVID-19) pandemic strains the healthcare system, radiology residents across the United States have become a vital part of the redeployed workforce. Through a series of four cases of COVID-19 patients encountered on the wards, we highlight the insight and unique set of skills redeployed radiology residents possess, which have been and will be essential to patient care during this crisis.
    keywords: covid-19; imaging; patient; radiology; residents; team
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        item: #1305 of 7819
          id: cord-264287-lq4awi0i
      author: Veerapandiyan, Aravindhan
       title: The care of patients with Duchenne, Becker, and other muscular dystrophies in the COVID‐19 pandemic
        date: 2020-05-05
       words: 1769
      flesch: 25
     summary: Infection Epidemiological characteristics of COVID-19 in Gansu province COVID-19 in children: current status Clinical features and treatment of COVID-19 patients in northeast Chongqing Epidemiological characteristics and clinical features of 32 critical and 67 noncritical cases of COVID-19 in Chengdu Centers for Disease Control and Prevention Evidence of SARS-CoV-2 infection in returning travelers from Wuhan, China Presymptomatic transmission of SARS-CoV-2-Singapore Coding in the world of COVID-19: non-face-to-face evaluation and management care Isolation of candidate cDNAs for portions of the Duchenne muscular dystrophy gene Diagnosis and management of Duchenne muscular dystrophy, part 2: respiratory, cardiac, bone health, and orthopaedic management Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management Diagnosis and management of Duchenne muscular dystrophy, part 3: primary care, emergency management, psychosocial care, and transitions of care across the lifespan European Centre for Disease Prevention and Control COVID-19 guidelines management of adrenal insufficiency risk after long-term systemic glucocorticoid therapy in Duchenne muscular dystrophy: clinical practice recommendations The PJ Nicholoff steroid protocol for Duchenne and Becker muscular dystrophy and adrenal suppression Tracheotomy in ventilated patients with COVID-19. COVID-19) Hydroxychloroquine causes severe vacuolar myopathy in a patient with chronic graft-versus-host disease Hydroxychloroquineinduced autophagic vacuolar myopathy with mitochondrial abnormalities Chloroquine and hydroxychloroquine in the era of SARS-CoV2: caution on their cardiac toxicity Assisted bicycle training delays functional deterioration in boys with Duchenne muscular dystrophy: the randomized controlled trial no use is disuse Prevention and management of limb contractures in neuromuscular diseases Attention deficit hyperactivity disorder and cognitive function in Duchenne muscular dystrophy: phenotype-genotype correlation Neuropsychological profile of duchenne muscular dystrophy COVID-19 and neuromuscular disorders How to cite this article:
    keywords: care; covid-19; duchenne; management; muscular; pandemic; patients
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        item: #1306 of 7819
          id: cord-264295-7ojvhwb0
      author: Maddaloni, Ernesto
       title: Cardiometabolic multimorbidity is associated with a worse Covid-19 prognosis than individual cardiometabolic risk factors: a multicentre retrospective study (CoViDiab II)
        date: 2020-10-01
       words: 4691
      flesch: 34
     summary: Age and sex adjusted regression models confirmed that Covid-19 patients with the primary composite outcome were more likely to have diabetes (adjusted odds ratio [ adj OR] 2.04, 95% confidence interval Overall our results confirm previous findings from other countries that Covid-19 patients with diabetes are more likely to require intensive care or to die, compared with Covid-19 patients without diabetes [12, 19, 20, 27] , and in addition suggest this association is driven by the presence of cardiometabolic multimorbidity rather than by diabetes alone.
    keywords: cardiometabolic; composite; covid-19; data; diabetes; outcome; patients; risk; study
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        item: #1307 of 7819
          id: cord-264356-3zu4w0a9
      author: Ino, Hiroyasu
       title: Vaccine mandate in long‐term care facilities
        date: 2020-10-01
       words: 1548
      flesch: 50
     summary: 11, 12 The elderly are typically given a larger dose of the flu vaccine, so there is a possibility that larger doses of COVID-19 vaccines are required for the elderly. We can apply the discussion of vaccine mandate for immigrants.
    keywords: covid-19; ltcfs; residents; telehealth; vaccine
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        item: #1308 of 7819
          id: cord-264412-2dwk06yd
      author: Dallavalle, Gianfranco
       title: Migraine Symptoms Improvement During the COVID-19 Lockdown in a Cohort of Children and Adolescents
        date: 2020-10-08
       words: 3318
      flesch: 36
     summary: The intensity of migraine symptoms changed during the lockdown 0, worsening; 1, stable; 2, improving; 3, resolution 9 The frequency of migraine symptoms was changing before the lockdown 0, worsening; 1, stable; 2, improving; 3, resolution 10 The frequency of migraine symptoms changed during the lockdown 0, worsening; 1, stable; 2, improving; 3, resolution FIGURE 1 | Association between migraine symptoms intensity (A) and frequency (B) before and during the lockdown. Previous research suggested that stressful psychological experiences in school and/or family may widely affect pediatric migraine symptoms (12) .
    keywords: covid-19; frequency; lockdown; migraine; patients; symptoms
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        item: #1309 of 7819
          id: cord-264449-p3tgjuj4
      author: Majumdar, PK
       title: Orthopaedic Surgery in Times of COVID-19 in India
        date: 2020-07-17
       words: 1735
      flesch: 41
     summary: Hence, this case restriction is not applicable for private hospitals and elective patients are still receiving care. We should continue to study best practices, such as the routine swabbing of pre-surgical patients 4 , anticoagulation in view of possible thrombotic tendencies 5 , and remain open to adopting them in practice.
    keywords: covid-19; hospital; orthopaedic; patients; surgeons; surgeries
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        item: #1310 of 7819
          id: cord-264462-4vfk99f5
      author: Piscoya, A.
       title: Efficacy and harms of remdesivir for the treatment of COVID-19: a systematic review and meta-analysis
        date: 2020-05-27
       words: 3568
      flesch: 52
     summary: The search was broadened for preprints at medRxiv.org, and for records of ongoing remdesivir RCTs at www.ClinicalTrials.gov, www.who.int/ictrp/about/en/, and www.clinicaltrialsregister.eu/. 16 On March 20 th 2020, the primary outcome was changed to a new 8-point ordinal severity scale, in which a subdivision was made on hospitalized patients (i.e. 5=hospitalized, not requiring supplemental oxygenrequiring ongoing medical care, and 6=hospitalized, not requiring supplemental oxygen -no longer requires ongoing medical care)
    keywords: covid-19; funder; medrxiv; patients; perpetuity; preprint; remdesivir; review
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        item: #1311 of 7819
          id: cord-264510-3wdquuzy
      author: Li, Meng
       title: Chest CT features and their role in COVID-19
        date: 2020-04-16
       words: 2084
      flesch: 42
     summary: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Chest radiographic and CT findings of the 2019 novel coronavirus disease (COVID-19): analysis of nine patients treated in Korea Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2 Chest CT findings in 2019 novel coronavirus (2019-nCoV) infections from Wuhan, China: key points for the radiologist Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection Chest CT findings in patients with Corona virus disease 2019 and its relationship with clinical features Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia Pre-and posttreatment chest CT findings: 2019 novel coronavirus (2019-nCoV) pneumonia Evolution of CT manifestations in a patient recovered from 2019 novel coronavirus (2019-nCoV) pneumonia in Wuhan, China Novel coronavirus (COVID-19) pneumonia: serial computed tomography findings The clinical and chest CT features associated with severe and critical COVID-19 pneumonia Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study Radiographic and CT features of viral pneumonia Imaging of pulmonary viral pneumonia Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT Pulmonary pathology of early-phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer Pathological findings of COVID-19 associated with acute respiratory distress syndrome Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Sensitivity of chest CT for COVID-19: comparison to RT-PCR Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Chest CT for typical 2019-nCoV pneumonia: relationship to negative RT-PCR testing Use of chest CT in combination with negative RT-PCR assay for the 2019 novel coronavirus but high clinical suspicion Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical features predicting mortality risk in patients with viral pneumonia: the MuLBSTA score CT imaging of coronavirus disease 2019 (COVID-19): from the qualitative to quantitative Outbreak of novel coronavirus (COVID-19): what is the role of radiologists? CT findings can change as the disease progresses.
    keywords: coronavirus; covid-19; novel; pneumonia
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        item: #1312 of 7819
          id: cord-264535-zhz9wzh9
      author: Kow, Chia Siang
       title: Metformin use amid coronavirus disease 2019 pandemic
        date: 2020-06-09
       words: 417
      flesch: 41
     summary: 8 Metformin and COVID-19: anovel deal of an old drug Effectiveness of metformin on weight loss in non-diabetic individuals with obesity A randomized trial of a low-carbohydrate diet vs orlistat plus a low-fat diet for weight loss Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo-controlled trial Long-term metformin use and vitamin B12 deficiency in the diabetes prevention program outcomes study Immunomodulation by vitamin B12: augmentation of CD8+ T lymphocytes and natural killer (NK) cell activity in vitamin B12-deficient patients by methyl-B12 treatment Functional exhaustion of antiviral lymphocytes in COVID-19 patients Salpeter Posthumous EE. intestinal absorption of vitamin B12 in up to 30% of metformin-treated patients and lowers serum vitamin B12 concentrations by 5% to 10%.
    keywords: b12; metformin
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        item: #1313 of 7819
          id: cord-264538-hzb2fkj5
      author: Tadic, Marijana
       title: COVID‐19 and arterial hypertension: Hypothesis or evidence?
        date: 2020-07-06
       words: 2014
      flesch: 33
     summary: retrospective study Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical features of 85 fatal cases of COVID-19 from Wuhan: a retrospective observational study Clinical features of patients infected with 2019 novel coronavirus in Wuhan Comorbidity and its impact on 1590 patients with Covid-19 in China: a nationwide analysis Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 (COVID-19) in Wuhan, China: a retrospective study Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis Prevalence of underlying diseases in hospitalized patients with COVID-19: a systematic review and meta-analysis Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation COVID-19, ACE2 and the cardiovascular consequences Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis Controversies of renin-angiotensin system inhibition during the COVID-19 pandemic Preventing a COVID-19 pandemic: ACE inhibitors as a potential risk factor for fatal COVID-19 Can angiotensin receptor-blocking drugs perhaps be harmful in the COVID-19 pandemic? Status of hypertension in China: results from the China Hypertension Survey Prevalence, awareness, treatment, and control of hypertension in China: data from 107 million adults in a population-based screening study (China PEACE Million Persons Project) Renin-Angiotensin-Aldosterone System Blockers and the Risk of Covid-19 Renin-Angiotensin-Aldosterone System Inhibitors and Risk of Covid-19 Association of Renin-Angiotensin System Inhibitors With Severity or Risk of patients with hypertension hospitalized for coronavirus disease 2019 (COVID-19) infection in Wuhan, China Association of inpatient use of angiotensin converting enzyme inhibitors and angiotensin ii receptor blockers with mortality among patients with hypertension hospitalized with COVID-19 Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Renin-Angiotensin System Inhibition in Cardiovascular Patients at the Time of COVID19: Even though these data demonstrated that the prevalence of hypertension in COVID-19 patients with lethal outcome was high, [7] [8] [9] [10] 14, 17 it has still been debated whether hypertension was a predictor of mortality independently of other cardiovascular risk factors (age, obesity, diabetes) and comorbidities (coronary artery disease, heart failure, atrial fibrillation, cerebrovascular disease, renal impairment).
    keywords: covid-19; disease; hypertension; patients
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        item: #1314 of 7819
          id: cord-264560-hxvadp24
      author: Liu, Jui-Yao
       title: Analysis of Imported Cases of COVID-19 in Taiwan: A Nationwide Study
        date: 2020-05-09
       words: 4345
      flesch: 56
     summary: Time from arrival to disease confirmation for imported COVID-19 cases in Taiwan from 21 January to 6 April 2020. The incidence of locally acquired COVID-19 cases remains sporadic although there are hundreds of imported COVID-19 cases in Taiwan (Figure 7) .
    keywords: arrival; cases; covid-19; days; disease; home; symptoms
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        item: #1315 of 7819
          id: cord-264563-c3wbie4i
      author: Karni, N.
       title: Self-rated smell ability enables highly specific predictors of COVID-19 status: a case control study in Israel
        date: 2020-08-01
       words: 1461
      flesch: 50
     summary: [3, 4] and in general press, and it is currently 70 well established that taste and smell loss is common in COVID-19 patients The severity of smell and taste loss in COVID-19 patients is striking: 80 these sensory abilities were reduced by -79.7 ± 28.7, -69.0 ± 32.6 (mean ± SD), 81 respectively, as reported by about 4000 participants using a 0-100 visual analog scale 82 (VAS)
    keywords: classifier; covid-19; smell; taste
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        item: #1316 of 7819
          id: cord-264578-hwq1k866
      author: Jiang, Ying
       title: The association between COVID-19 deaths and short-term ambient air pollution/meteorological condition exposure: a retrospective study from Wuhan, China
        date: 2020-08-15
       words: 2677
      flesch: 44
     summary: key: cord-264578-hwq1k866 authors: Jiang, Ying; Xu, Jing title: The association between COVID-19 deaths and short-term ambient air pollution/meteorological condition exposure: a retrospective study from Wuhan, China date: 2020-08-15 journal: Air Qual Atmos Health DOI: 10.1007/s11869-020-00906-7 sha: doc_id: 264578 cord_uid: hwq1k866 The emergence of coronavirus disease 2019 (COVID-19) has become a worldwide pandemic after its first outbreak in Wuhan, China. The Pearson and Poisson regression models were used accordingly to understand the association between COVID-19 deaths and each risk factor.
    keywords: air; association; covid-19; deaths
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        item: #1317 of 7819
          id: cord-264610-kxebc12r
      author: Chen, Yu
       title: Clinical characteristics of IgG4-RD patients infected with COVID-19 in Hubei, China
        date: 2020-05-16
       words: 1749
      flesch: 39
     summary: The symptoms such as fever and cough and radiologic features were similar to other COVID-19 patients. In our study, patient 2 took a long time for SARS-Cov-2 nucleic acid to turn negative, which may implicated that the viral load in such patients may need to be monitored for a longer time after discharge.
    keywords: covid-19; disease; igg4; patients
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        item: #1318 of 7819
          id: cord-264614-2x7cdul3
      author: Díaz-Guio, Diego Andrés
       title: COVID-19: Biosafety in the Intensive Care Unit
        date: 2020-08-27
       words: 3860
      flesch: 44
     summary: However, the median time from intubation to death of COVID-19 patients has been reported to be on the 7th day [41] . This article aims to show the different strategies to prevent the widespread of the disease to critical care healthcare workers based on the review of the recent literature and the author's experience with the personal protective equipment (PPE) in the care of patients with COVID-19 and work on human factors in crisis management.
    keywords: care; covid-19; equipment; healthcare; icu; patients; personnel; respirators; use; workers
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        item: #1319 of 7819
          id: cord-264642-veqyvtn4
      author: Tzu-Hsuan Chen, Daniel
       title: The psychosocial impact of the COVID-19 pandemic on changes in smoking behavior: Evidence from a nationwide survey in the UK
        date: 2020-10-23
       words: 1919
      flesch: 43
     summary: To analyze the relationship between smoking behavior change and the respondents' psychosocial characteristics, Pearson's χ 2 (or Fisher's exact test when appropriate) and Cramer's V statistics were used. Of the 486 current smokers surveyed, 329 current smokers who reported data on smoking behavior change were included in the analysis.
    keywords: covid-19; health; pandemic; smokers; smoking
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        item: #1320 of 7819
          id: cord-264647-9r443j3l
      author: Talamonti, G.
       title: Spinal epidural abscess in COVID-19 patients
        date: 2020-09-10
       words: 2925
      flesch: 47
     summary: key: cord-264647-9r443j3l authors: Talamonti, G.; Colistra, Davide; Crisà, Francesco; Cenzato, Marco; Giorgi, Pietro; D’Aliberti, Giuseppe title: Spinal epidural abscess in COVID-19 patients date: 2020-09-10 journal: J Neurol DOI: 10.1007/s00415-020-10211-z sha: doc_id: 264647 cord_uid: 9r443j3l OBJECTIVE: To report the peculiarity of spinal epidural abscess in COVID-19 patients, as we have observed an unusually high number of these patients following the outbreak of SARS-Corona Virus-2. To our knowledge, cases of spinal epidural abscess in COVID-19 patients have not been reported to date.
    keywords: abscess; cases; covid-19; patients; sea; spinal
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        item: #1321 of 7819
          id: cord-264651-cqxmpxyq
      author: Lee, Shawna J.
       title: Parenting Activities and the Transition to Home-based Education During the COVID-19 Pandemic
        date: 2020-10-13
       words: 8174
      flesch: 48
     summary: Parents' use of technology for child education and entertainment was assessed using an open-ended question, What online resources have been the most helpful in educating your child at home? With regard to the use of technology for child education during COVID-19, we asked parents to tell us about the online tools that they were using to support at-home educational activities.
    keywords: anxiety; children; covid-19; education; health; home; pandemic; parents; resources; school; study
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        item: #1322 of 7819
          id: cord-264673-67zopf7s
      author: Shi, Hongbo
       title: The inhibition of IL-2/IL-2R gives rise to CD8(+) T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia
        date: 2020-06-08
       words: 3369
      flesch: 49
     summary: Notably, the absolute lymphocyte count in critical patients was significantly lower than that in common or severe patients, but there was no difference between common patients and severe patients (Fig. 1a ). The level of interleukin-2 (IL-2) in critical patients was significantly lower than that in severe patients, whereas the level of IL-2 in severe patients was higher than that in normal controls and common patients (Fig. 3a) .
    keywords: cd8; cells; controls; covid-19; fig; patients; pneumonia
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        item: #1323 of 7819
          id: cord-264697-b3wd6gww
      author: Ma, Xiaoxu
       title: Characteristic of 523 COVID-19 in Henan Province and a Death Prediction Model
        date: 2020-09-08
       words: 4490
      flesch: 48
     summary: The level of D-dimer at admission was significantly higher in severe patients The alanine aminotransferase, lactate dehydrogenase and creatine kinase in the severe were significantly higher than those in the mild, and the non-survivors was more obviously, the difference was significant. We constructed classification models to evaluate death risk for severe patients.
    keywords: cases; covid-19; data; death; henan; non; patients; study; survivors
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        item: #1324 of 7819
          id: cord-264769-gp2tie7k
      author: XiangNg, Qin
       title: A Framework to Deal with Uncertainty in the Age of COVID-19
        date: 2020-06-20
       words: 747
      flesch: 46
     summary: Research studies are being published at a feverish pace (Laine et al., 2020) ; researchers have now highlighted and then disputed a previously underappreciated reservoir of asymptomatic 'spreaders' (Gandhi, Yokoe & Havlir, 2020; Wei et al., 2020) . Our current understanding of the SARS-CoV-2 is still limited, especially with regard to the epidemiologic features of the virus (Wang et al., 2020) .
    keywords: covid-19
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        item: #1325 of 7819
          id: cord-264779-71s7e18i
      author: Neumann, Natalie R.
       title: Medical Toxicology and COVID-19: Our Role in a Pandemic
        date: 2020-04-30
       words: 1930
      flesch: 35
     summary: Lastly, poison centers, historically considered an underutilized source for reporting adverse drug reactions, may be more mindful of tracking and reporting toxicity from novel therapies [26] . The Lancet Respiratory Medicine FDA advises patients on use of nonsteroidal anti-inflammatory drugs (NSAIDs) for COVID-19 A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirusinduced lung injury Liver injury in COVID-19: management and challenges Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Pathological findings of COVID-19 associated with acute respiratory distress syndrome Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study COVID-19 and the liver: little cause for concern Insufficient stocking of poisoning antidotes in hospital pharmacies Availability of antidotes at acute care hospitals in Ontario National audit of antidote stocking in acute hospitals in the UK Expert consensus guidelines for stocking of antidotes in hospitals that provide emergency care Royal College of Emergency Medicine and National Poisons Information Service Reporting of adverse drug reactions by poison control centres in the US MedWatch:
    keywords: covid-19; drug; hospital; information; medical; patients; toxicology
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        item: #1326 of 7819
          id: cord-264785-kkd2pyp3
      author: Plevinsky, Jill M
       title: The Impact of COVID-19 on Pediatric Adherence and Self-Management
        date: 2020-09-26
       words: 3144
      flesch: 14
     summary: Barriers, solutions, results Patient-reported outcomes for pediatric adherence and self-management: A systematic review Adherence to pediatric medical regimens Functional neuroimaging of working memory in survivors of childhood brain tumors and healthy children: Associations with coping and psychosocial outcomes Major depressive disorder is associated with broad impairments on neuropsychological measures of executive function: A meta-analysis and review Exploring the intersection of executive function and medication adherence in school-age children with asthma A longitudinal study of depressive symptoms, neuropsychological functioning, and medical responsibility in youth with spina bifida: Examining direct and mediating pathways Considerations and future directions for conducting clinical research with pediatric populations during the COVID-19 pandemic The effect of screen-to-screen versus face-to-face consultation on doctor-patient communication: An experimental study with simulated patients COVID-19 exacerbating inequalities in the US Using the school environment to promote physical activity and healthy eating We also discuss how barriers to pediatric adherence and self-management exacerbated by the pandemic may disproportionately affect underserved and vulnerable populations, potentially resulting in greater health disparities.
    keywords: adherence; covid-19; health; management; pandemic; self
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        item: #1327 of 7819
          id: cord-264793-0wvif337
      author: Miró, Òscar
       title: Frequency of five unusual presentations in patients with COVID-19: results of the UMC-19-S(1)
        date: 2020-08-26
       words: 2625
      flesch: 34
     summary: Similar results were found in all OR when comparing COVID patients with non-COVID patients recruited during the pre-COVID and the COVID periods separately (Fig. 1 ). The second notable finding is that Guillain-Barré syndrome, spontaneous pneumothorax and acute myocarditis were more frequently observed in COVID patients than in non-COVID patients in the ED.
    keywords: covid; covid-19; patients; syndrome
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        item: #1328 of 7819
          id: cord-264811-xbeipob9
      author: Choi, Yongin
       title: Assessment of Social Distancing for Controlling COVID-19 in Korea: An Age-Structured Modeling Approach
        date: 2020-10-14
       words: 6332
      flesch: 52
     summary: Table 1 shows the incidence data by age group and the sources of infection in the target area during the period. More precisely, the location-specific contact matrix M is written as [25] where each element m ij denotes the mean number of contacts an individual in age group i makes with individuals in age group j per day.
    keywords: age; age groups; contact; covid-19; distancing; groups; incidence; transmission
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        item: #1329 of 7819
          id: cord-264814-v4wnmg03
      author: Flanagan, Katie L.
       title: Progress and Pitfalls in the Quest for Effective SARS-CoV-2 (COVID-19) Vaccines
        date: 2020-10-02
       words: 15157
      flesch: 34
     summary: Med Hypotheses Antibodies against trimeric S glycoprotein protect hamsters against SARS-CoV challenge despite their capacity to mediate FcgammaRII-dependent entry into B cells in vitro Early death after feline infectious peritonitis virus challenge due to recombinant vaccinia virus immunization Monoclonal antibody analysis of neutralization and antibody-dependent enhancement of feline infectious peritonitis virus Monoclonal antibodies to the spike protein of feline infectious peritonitis virus mediate antibody-dependent enhancement of infection of feline macrophages Evaluation of modified vaccinia virus ankara based recombinant SARS vaccine in ferrets Molecular mechanism for antibody-dependent enhancement of coronavirus entry Distinct systems serology features in children, elderly and COVID patients. The standardization of a range of assays to support vaccine studies, such as viral neutralization assays, to enable comparison of different vaccine candidates in different populations will be key to facilitating vaccine development, an issue which represents a current focus of the WHO (43).
    keywords: cell; challenge; coronavirus; cov-2; covid-19; development; disease; dna; human; immunity; infection; key; nabs; patients; phase; protein; response; safety; sars; studies; table; trials; vaccine; virus
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        item: #1330 of 7819
          id: cord-264829-ynel6ore
      author: Momtazmanesh, Sara
       title: Cardiovascular disease in COVID-19: a systematic review and meta-analysis of 10,898 patients and proposal of a triage risk stratification tool
        date: 2020-07-13
       words: 7975
      flesch: 43
     summary: Interact Cardiovasc Thorac Surg Optimally estimating the sample mean from the sample size, median, mid-range, and/or mid-quartile range Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range Hospitalization and critical care of 109 decedents with COVID-19 pneumonia in Wuhan, China Clinical features and treatment of COVID-19 patients in northeast Chongqing Analysis of myocardial injury in patients with COVID-19 and association between concomitant cardiovascular diseases and severity of COVID-19 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 (COVID-19) in Wuhan, China: a retrospective study Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 (COVID-19) in Wuhan, China: a retrospective study Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan: a retrospective observational study Prognostic value of NT-proBNP in patients with severe COVID-19 Hospitalization rates and characteristics of patients hospitalized with laboratory-confirmed coronavirus disease 2019-COVID-NET, 14 States Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19) China Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan Clinical analysis of 150 cases of 2019 novel coronavirus infection in Nanyang City Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2 Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Association of inpatient use of angiotensin converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized With COVID-19 Clinical characteristics of 161 cases of corona virus disease 2019 (COVID-19) in Changsha Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Heart failure and liver disease: cardiohepatic interactions Cardiohepatic interactions in heart failure: an overview and clinical implications Right Heart Failure and Cardiorenal Syndrome An Update on the pathophysiology and treatment of cardiorenal syndrome Cardiorenal syndrome: multi-organ dysfunction involving the heart, kidney and vasculature Acute myocarditis presenting as a reverse Tako-Tsubo syndrome in a patient with SARS-CoV-2 respiratory infection Coronavirus fulminant myocarditis treated with glucocorticoid and human immunoglobulin First case of COVID-19 complicated with fulminant myocarditis: a case report and insights Acute pulmonary embolism in COVID-19 patients on CT angiography and relationship to Ddimer levels COVID-19 pneumonia with hemoptysis: acute segmental pulmonary emboli associated with novel coronavirus infection Severe Acute Proximal Pulmonary Embolism and COVID-19:
    keywords: acute; analysis; clinical; coronavirus; covid-19; disease; frequency; icu; injury; levels; patients; studies
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        item: #1331 of 7819
          id: cord-264843-cwtdkylo
      author: Chen, Justin A.
       title: COVID-19 and telepsychiatry: Early outpatient experiences and implications for the future
        date: 2020-07-09
       words: 4034
      flesch: 36
     summary: In this paper, the term telepsychiatry is used to refer to real-time video and/or audio connection between mental health clinicians and patients, including mental health services delivered by telephone. Early analyses suggest that these changes have enabled mental health clinicians to continue to provide vital care at a challenging time.
    keywords: care; clinicians; covid-19; patients; person; telehealth; telepsychiatry; treatment
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        item: #1332 of 7819
          id: cord-264907-y4vefr98
      author: Renke, Christine
       title: Utilization of Pediatric Nurse Practitioners as Adult Critical Care Providers During the COVID-19 Pandemic: A Novel Approach
        date: 2020-06-17
       words: 2659
      flesch: 43
     summary: These processes were necessary to permit PNPs to practice to their full scope and ability in the provision of care to an overwhelming number of COVID-19 ICU patients. The team's focus expanded beyond individual patient care to include overall global health.
    keywords: apps; care; covid-19; icu; pandemic; patients; pnps; providers
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        item: #1333 of 7819
          id: cord-264919-0jlg2gkc
      author: Hopp, Marie-Thérèse
       title: Unravelling the debate on heme effects in COVID-19 infections
        date: 2020-06-12
       words: 7102
      flesch: 40
     summary: Clinical observations revealed their upregulation in COVID-19 patients as well as during hemolytic events (Dutra and Bozza, 2014; Humayun et al., 2020; Ye et al., 2020) , which highlights even more the TLR4 signaling pathway in both situations. COVID-19 is caused by infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is accompanied by pneumonia, acute respiratory distress syndrome (ARDS) associated with a cytokine storm, and death in the most severe cases (Ye et al., 2020; Zhou et al., 2020a) .
    keywords: ace2; binding; cell; cov-2; covid-19; et al; figure; heme; interaction; motifs; patients; protein; sars; system; tmprss2
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        item: #1334 of 7819
          id: cord-264942-9u2k5ctm
      author: Lusczek, E. R.
       title: Characterizing COVID-19 Clinical Phenotypes and Associated Comorbidities and Complication Profiles
        date: 2020-09-14
       words: 3283
      flesch: 39
     summary: In this study, we not only characterized three clinical phenotypes, but extended findings outside of the ICU by characterizing the association of comorbidities with clinical phenotype and the association of clinical phenotypes with in-hospital complication and clinical outcomes. This is one of the first studies to report on clinical phenotypes associated with COVID-19.
    keywords: covid-19; medrxiv; patients; perpetuity; phenotype; preprint; review
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        item: #1335 of 7819
          id: cord-264957-po7wys3s
      author: Singh, A.
       title: Covid-19 Pandemic- Pits and falls of major states of India.
        date: 2020-06-20
       words: 3739
      flesch: 58
     summary: With increasing number of Covid-19 cases, testing also has increased however not in the similar proportion and thus by developed nation standard we are lagging. India has 287157 confirmed Covid-19 cases out of which 48 percent patients constitute the active cases and 49 percent patients have recovered as on June 10 th 2020
    keywords: cases; covid-19; india; license; preprint
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        item: #1336 of 7819
          id: cord-264967-a822exap
      author: Fu, Yue-qiang
       title: Impact of blood analysis and immune function on the prognosis of patients with COVID-19
        date: 2020-04-22
       words: 4388
      flesch: 55
     summary: Another study also indicated that COVID-19 patients in the death group had significantly lower lymphocyte count on admission than the recovered group [7] , however they did not explore changes in lymphocyte subsets. [13] found that CD4+ T cells, CD8+ T cells, B cells and natural killer (NK) cells decreased in COVID-19 patients, and severe cases had a lower level than mild cases.
    keywords: count; covid-19; group; license; lymphocyte; patients; preprint
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        item: #1337 of 7819
          id: cord-264974-hspek930
      author: Timmis, Kenneth
       title: The COVID‐19 pandemic: some lessons learned about crisis preparedness and management, and the need for international benchmarking to reduce deficits
        date: 2020-05-03
       words: 7225
      flesch: 29
     summary: • Governments and health systems must subject national health systems, and national health system crisis preparedness, to international benchmark scrutiny, and transparently strive for attainment of best international standards. The number of individuals who try to keep it in the forefront of memory, in order to institute new measures that adequately protect us from the next crisis, and there will undoubtedly be new crises (see above), will be few and far between.
    keywords: countries; cov-2; covid-19; crisis; e.g.; health; healthcare; hospitals; infection; outbreak; pandemic; patients; preparedness; public; sars; systems
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        item: #1338 of 7819
          id: cord-264976-6n9cdex6
      author: Corse, Tanner
       title: Clinical Outcomes of COVID-19 Patients with Pre-existing, Compromised Immune Systems: A Review of Case Reports
        date: 2020-10-18
       words: 6122
      flesch: 35
     summary: To learn more about such individuals, we conducted a search and review of published reports on the clinical characteristics and outcomes of COVID-19 patients with pre-existing, compromised immune systems. Most symptomatic COVID-19 patients recover with supportive care in hospitals; however, a small but significant percentage of COVID-19 patients are at risk of developing acute respiratory distress syndrome (ARDS) or respiratory failure [7, 8] .
    keywords: cov-2; covid-19; mortality; patients; rate; recipients; sars; table; transplant
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        item: #1339 of 7819
          id: cord-264979-pc1s093k
      author: Zhou, Yan
       title: Management for patients with pediatric surgical disease during the COVID-19 epidemic
        date: 2020-04-20
       words: 973
      flesch: 37
     summary: Besides, although it remains unclear whether infected children with cancer are associated with poor prognosis, it seems that the tumor itself and its corresponding treatment may weaken the immune response to pathogenic microorganisms, and further make the COVID-19 worse. In a recent report about infected children from Wuhan, 18 of 20 children were cured with an average stay of 12.9 days (8-20 days)
    keywords: children; covid-19; treatment
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        item: #1340 of 7819
          id: cord-264986-glm2qcuz
      author: Tam, Cheuk Chi
       title: Psychological Distress Among HIV Healthcare Providers During the COVID-19 Pandemic in China: Mediating Roles of Institutional Support and Resilience
        date: 2020-10-21
       words: 4831
      flesch: 31
     summary: However, limited COVID-19 research examined the mechanisms of psychological distress among HIV healthcare providers. Psychological distress among HIV healthcare providers in China could be particularly concerning due to several COVID-19 related stressors at HIV clinics.
    keywords: covid-19; distress; healthcare; hiv; pandemic; providers; resilience; stressors; support
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        item: #1341 of 7819
          id: cord-265006-m1dmgcd1
      author: Kow, Chia Siang
       title: Do the meta-analyses provide a clean bill of health to the use of renin-angiotensin system inhibitors in COVID-19?
        date: 2020-08-08
       words: 843
      flesch: 30
     summary: Patients with these conditions too need long-term usage of RAS inhibitors, where increased expression of ACE2 receptor, which is the hypothesized pathological A c c e p t e d M a n u s c r i p t mechanism leading to worse outcomes among COVID-19 patients receiving RAS inhibitors, could also occur in the users of RAS inhibitors for indications other than hypertension Secondly, some of these systematic reviews and meta-analyses included studies or only involved findings on COVID-19 patients with concurrent hypertension.
    keywords: covid-19; inhibitors
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        item: #1342 of 7819
          id: cord-265022-p5cab562
      author: Kotfis, Katarzyna
       title: COVID-19: ICU delirium management during SARS-CoV-2 pandemic
        date: 2020-04-28
       words: 5433
      flesch: 28
     summary: The Intensive Care Delirium Screening Checklist (ICDSC)--translation and validation of intensive care delirium checklist in accordance with guidelines A novel coronavirus from patients with pneumonia in China Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia Clinical features of patients infected with 2019 novel coronavirus in Wuhan Fair Allocation of Scarce Medical Resources in the Time of Covid-19 Sedative and analgesic medications are independent risk factors in ICU patients for transitioning into delirium Use of medications with anticholinergic effect predicts clinical severity of delirium symptoms in older medical inpatients Caring for critically ill patients with the ABCDEF bundle: results of the ICU liberation collaborative in over 15,000 adults The ABCDEF bundle: science and philosophy of how ICU liberation serves patients and families Improving hospital survival and reducing brain dysfunction at seven California community hospitals: implementing PAD guidelines via the ABCDEF bundle in 6,064 patients Clinical and team management in the COVID-ICU: successful strategies from the first week Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways Multiple organ infection and the pathogenesis of SARS Neurotropic virus tracing suggests a membranous-coatingmediated mechanism for transsynaptic communication SARS: clinical features and diagnosis The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice Neuroinvasion by human respiratory coronaviruses Middle East respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human Dipeptidyl peptidase 4 Novel coronavirus is putting the whole world on alert Neurotropism of human coronavirus 229E Characteristics of a coronavirus (strain 67N) of pigs Detection of coronavirus in the central nervous system of a child with acute disseminated encephalomyelitis Neurologic complications of coronavirus infections Coronavirus infections in the central nervous system and respiratory tract show distinct features in hospitalized children COVID-19-associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features. However, the standard of care for ICU patients, including delirium management, must remain the highest quality possible with an eye towards long-term survival and minimization of issues related to post-intensive care syndrome (PICS).
    keywords: acute; brain; care; coronavirus; cov-2; covid-19; delirium; icu; management; patients; risk; sars; unit
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        item: #1343 of 7819
          id: cord-265049-uwzmvlr4
      author: Tuge Deressa, Chernet
       title: Modeling and Optimal Control Analysis of Transmission Dynamics of COVID-19: The Case of Ethiopia
        date: 2020-10-09
       words: 4220
      flesch: 40
     summary: Since the first case of COVID 19, various mathematicians around the world develop different mathematical models to understand the transmission dynamics of the virus, estimated the basic reproductive number and investigated effects of different intervention strategies via optimal control analysis. Mathematical models developed were mainly used to investigate the effects of different Non-pharmaceutical intervention strategies via simulation using different computing soft-wares
    keywords: cases; control; covid-19; mathematical; model; number; transmission
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        item: #1344 of 7819
          id: cord-265052-hfuvm1oh
      author: Turan, Çağrı
       title: Change of the diagnostic distribution in applicants to dermatology after COVID ‐19 pandemic: What it whispers to us?
        date: 2020-06-12
       words: 4119
      flesch: 50
     summary: It was determined that 9531 (9.2%) of 104142 applications to all clinical departments, except COVID-19 outpatient clinic, were made to dermatology outpatient clinics within 12 weeks (12 February-8 May 2020). All rights reserved. one or more of the following reasons: The risk perception of patients in this group is similar, the treatment plan for chronic diseases is pre-drawn, and some diseases do not cause severe deterioration in their QoL. The frequency decline in diseases such as verruca vulgaris, hyperpigmentation, skin tag, melanocytic nevus, seborrheic keratosis/solar lentigo suggested that these diseases do not affect the QoL too much or that such diseases can be ignored during the outbreak.
    keywords: applications; covid-19; dermatology; diseases; frequency; outpatient; patients; weeks
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        item: #1345 of 7819
          id: cord-265053-x70501t3
      author: Pourhomayoun, Mohammad
       title: Predicting Mortality Risk in Patients with COVID-19 Using Artificial Intelligence to Help Medical Decision-Making
        date: 2020-04-01
       words: 1860
      flesch: 44
     summary: A model of beds needed and available for Coronavirus patients Interactive Dimensionality Reduction for Improving Patient Adherence in Remote Health Monitoring Risk Prediction of Critical Vital Signs for ICU Patients Using Recurrent Neural Network Multiple model analytics for adverse event prediction in remote health monitoring systems Interactive Predictive Analytics for Enhancing Patient Adherence in Remote Health Monitoring Multi-label Classification of Single and Clustered Cervical Cells Using Deep Convolutional Networks Context-Aware Data Analytics for Activity Recognition Machine Learning The Nature of Statistical Learning Theory Random Forests This system can help hospitals, medical facilities, and caregivers decide who needs to get attention first before other patients, triage patients when the system is overwhelmed by overcrowding, and also eliminate delays in providing the necessary care. Finally, we used a separate dataset of COVID-19 patients to evaluate our developed model accuracy, and used confusion matrix to make an in-depth analysis of our classifiers and calculate the sensitivity and specificity of our model.
    keywords: covid-19; data; features; model; patients
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        item: #1346 of 7819
          id: cord-265077-7dh669jv
      author: Liu, Fang
       title: Clinico-Radiological Features and Outcomes in Pregnant Women with COVID-19 Pneumonia Compared with Age-Matched Non-Pregnant Women
        date: 2020-08-13
       words: 4658
      flesch: 44
     summary: The noise index (NI) and dose-length product (DLP) were 15 and 50-150 mGy·cm for pregnant women, while 7.99 and 250-400 mGy·cm for non-pregnant women. The clinical and chest CT features associated with severe and critical COVID-19 pneumonia Clinical and CT imaging features of the COVID-19 pneumonia: focus on pregnant women and children Pathological findings of COVID-19 associated with acute respiratory distress syndrome How to perform lung ultrasound in pregnant women with suspected COVID-19 Lung ultrasound can influence the clinical treatment of pregnant women with COVID-19 Lung ultrasound and computed tomographic findings in pregnant woman with COVID-19 Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome A case-controlled study comparing clinical course and outcomes of pregnant and non-pregnant women with severe acute respiratory syndrome All authors declare no potential conflict of interest relevant to this article.
    keywords: consolidation; covid-19; outcomes; patients; pneumonia; stage; study; women
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        item: #1347 of 7819
          id: cord-265078-u19e9j2w
      author: Xie, Jingui
       title: Association between ambient temperature and COVID-19 infection in 122 cities from China
        date: 2020-07-01
       words: 2806
      flesch: 49
     summary: Modeling zoonotic cutaneous leishmaniasis incidence in central Tunisia from 2009-2015: forecasting models using climate variables as predictors An initial investigation of the association between the SARS outbreak and weather: with the view of the environmental temperature and its variation Stability of Middle East respiratory syndrome coronavirus (MERS-CoV) under different environmental conditions A time-series study of the association of rainfall, relative humidity and ambient temperature with hospitalizations for rotavirus and norovirus infection among children in Hong Kong Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Non-linear effects of mean temperature and relative humidity on dengue incidence in Guangzhou Pathological findings of COVID-19 associated with acute respiratory distress syndrome A generalized additive model (GAM) was applied to explore the nonlinear relationship between mean temperature and COVID-19 confirmed cases.
    keywords: cases; covid-19; temperature
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        item: #1348 of 7819
          id: cord-265082-gjbabh4g
      author: Xuan, Tian-ming
       title: Primary percutaneous coronary intervention in a COVID-19 patient with ST-segment elevation myocardial infarction after lung transplantation: a case report
        date: 2020-05-09
       words: 1991
      flesch: 39
     summary: (e) ECG shows diffuse ST-segment elevation through V1 to V6 leads arteries, which affects coronary blood flow and leads to myocardial infarction, and Type 2 refers to an imbalance of myocardial blood supply/demand caused by specific factors that can lead to myocardial ischemic infarction. Recent studies have shown that COVID-19 patients also have cytokine storms caused by the imbalance of T helper type 1 (Th1) and Th2 responses, and the levels of inflammatory factors IL-4, IL-10, and IL-6 in tissue samples were increased (Chen et al., 2020; Huang et al., 2020) .
    keywords: coronary; covid-19; day; infarction; lung; patient; transplantation
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        item: #1349 of 7819
          id: cord-265100-i49m4y0e
      author: Moradzadeh, Rahmatollah
       title: The challenges and considerations of community-based preparedness at the onset of COVID-19 outbreak in Iran, 2020
        date: 2020-04-03
       words: 1543
      flesch: 59
     summary: Among 20 COVID-19 cases, three villages near Delijan had positive cases, but other COVID-19 cases (n = 17) were observed in the city. The total number of COVID-19 cases has been 266 073 across the world
    keywords: cases; city; covid-19; health
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        item: #1350 of 7819
          id: cord-265111-d44ireu5
      author: D’Ardes, Damiano
       title: Duration of COVID-19: Data from an Italian Cohort and Potential Role for Steroids
        date: 2020-08-31
       words: 3105
      flesch: 36
     summary: Notwithstanding the many limitations of these study, such as the small sample size, these observations could add new information to the settings of prevention and treatment of COVID-19 patients, contributing to the worldwide battle against the SARS-CoV-2 pandemic. We considered a cohort of patients recovered from COVID-19 showing that the median disease duration between onset and end of COVID-19 symptoms was 27.5 days (interquartile range (IQR): 17.0–33.2) and that the median duration between onset of symptoms and microbiological healing, defined by two consecutive negative nasopharyngeal swabs, was 38 days (IQR: 31.7–50.2).
    keywords: cov-2; covid-19; disease; duration; patients; sars; shedding
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        item: #1351 of 7819
          id: cord-265119-j4u4fbba
      author: Alakwaa, Fadhl M.
       title: Repurposing Didanosine as a Potential Treatment for COVID-19 Using Single-Cell RNA Sequencing Data
        date: 2020-04-14
       words: 975
      flesch: 52
     summary: In an urgent response to this pandemic, I developed a bioinformatics pipeline to identify compounds and drug candidates to potentially treat COVID-19. In an urgent response to this pandemic, I developed a bioinformatics pipeline to identify compounds and drug candidates to potentially treat COVID-19.
    keywords: covid-19; drugs; score
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        item: #1352 of 7819
          id: cord-265155-jbvrcjx8
      author: Aroniadis, Olga C.
       title: Current Knowledge and Research Priorities in the Digestive Manifestations of COVID-19
        date: 2020-04-22
       words: 1609
      flesch: 29
     summary: Evidence for gastrointestinal infection of SARS-CoV-Gastroenterology Diarrhea during COVID-19 infection: pathogenesis, epidemiology, prevention and management Digestive Symptoms in COVID-19 Patients with Mild Disease Severity: Clinical Presentation, Stool Viral RNA Testing, and Outcomes Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional Prolonged presence of SARS-CoV-2 viral RNA in faecal samples Liver injury in COVID-19: management and challenges Pathological findings of COVID-19 associated with acute respiratory distress syndrome Pancreatic injury patterns in patients with COVID-19 pneumonia Considerations in performing endoscopy during the COVID-19 pandemic On behalf of the AGA, AGA Institute Rapid Recommendations for Gastrointestinal Procedures During the COVID-19 Pandemic Clinical Characteristics of Coronavirus Disease 2019 in China Microbiota-driven tonic interferon signals in lung stromal cells protect from influenza virus infection Virus detected in stool 50-55% 1,3,5 Importantly, studies suggest that a fraction of COVID-19 patients experience digestive manifestations in the absence of respiratory symptoms or fever -representing a potential source of exposure for unsuspecting health care workers.
    keywords: covid-19; endoscopy; patients; sars; symptoms
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        item: #1353 of 7819
          id: cord-265169-bmwdpzqe
      author: Co, Christian Oliver C.
       title: Acute Stroke Care Algorithm in a Private Tertiary Hospital in the Philippines During the COVID-19 Pandemic: A Third World Country Experience
        date: 2020-06-20
       words: 1769
      flesch: 43
     summary: In fact, 4.9% of COVID-19 infected patients are expected to have acute stroke (2) and large vessel occlusion can present as stroke in the young in COVID-19 positive patients (8) . This pandemic has shaped the stroke team's approach in the management of acute stroke patients.
    keywords: acute; covid-19; emergency; pandemic; patients; stroke
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        item: #1354 of 7819
          id: cord-265170-yv04ijsm
      author: Ceccarelli, Giancarlo
       title: Probiotics and COVID-19
        date: 2020-07-13
       words: 1128
      flesch: 30
     summary: As the world waits in semi-lockdown mode, continued scientific progress for COVID-19 prevention or treatment is highly important, and probiotics represent one option. Importantly, gut microbiome configuration was associated with COVID-19 disease severity, and altered gut microbiota persisted even after clearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), suggesting that the virus might inflict prolonged harm to human microbiome homoeostasis.
    keywords: cov-2; covid-19; probiotics; sars
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        item: #1355 of 7819
          id: cord-265172-rn9pkk52
      author: Michiwaki, Yuhei
       title: Emergent carotid artery stenting following intravenous alteplase infusion after rapid negative diagnosis for COVID-19 by loop-mediated isothermal amplification assay: A case report
        date: 2020-10-09
       words: 2435
      flesch: 40
     summary: During the COVID-19 pandemic, the LAMP assay for COVID-19 detection might be a suitable diagnostic strategy preceding stroke treatment because of the rapid turnaround time. During the COVID-19 pandemic, the LAMP assay for COVID-19 detection might be a suitable diagnostic strategy preceding stroke treatment because of the rapid turnaround time.
    keywords: covid-19; ecas; lamp; stroke
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        item: #1356 of 7819
          id: cord-265178-q7x7ec24
      author: Lyócsa, Štefan
       title: Fear of the coronavirus and the stock markets
        date: 2020-08-26
       words: 3335
      flesch: 51
     summary: gtrendsR: Perform and display Google trends queries Stock markets and the COVID-19 fractal contagion effects Correction to Automatic block-length selection for the dependent bootstrap by D. Politis and H. White Quantifying trading behavior in financial markets using Google Trends COVID-19 pandemic, oil prices, stock market, geopolitical risk 260 and policy uncertainty nexus in the US economy: Fresh evidence from the wavelet-based approach News sentiment and the investor fear gauge The importance of fear: investor sentiment and stock market returns The investor fear gauge Infected markets: Novel coronavirus, government interventions, and stock return volatility around the globe Financial markets under the global pandemic of COVID-19. The idea of using sentiment or fear to explain stock market volatility is certainly not new; several recent studies have used news, VIX, Twitter posts and other proxies to measure investors' sentiment and fear about the future (e.g., Whaley, 2000; Zhang et al., 2011; Huerta et al., 2011; Smales, 2014 Smales, , 2017 .
    keywords: coronavirus; covid-19; fear; google; market; pandemic; search; stock
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        item: #1357 of 7819
          id: cord-265197-kxfj3ziu
      author: DiMaria, Christina N
       title: Cognitive Bias in the COVID-19 Pandemic
        date: 2020-07-06
       words: 1318
      flesch: 53
     summary: For this reason, we suggest some guiding principles to prevent cognitive bias errors during the COVID-19 pandemic. The report illustrates the concept of cognitive bias during a pandemic and discusses strategies to ameliorate them.
    keywords: bias; covid-19; patient
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        item: #1358 of 7819
          id: cord-265230-ozyx8u64
      author: Takahari, Daisuke
       title: Managing a gastrointestinal oncology practice in Japan during the COVID-19 pandemic: single institutional experience in The Cancer Institute Hospital of Japanese Foundation for Cancer Research
        date: 2020-10-21
       words: 5756
      flesch: 38
     summary: Various reports have shown data indicating that cancer patients with COVID-19 have high morbidity and mortality rates. For cancer patients, of course, hospital visits for treatment and assessments are not subject to restriction, but the visits themselves can be a risk of infection, especially for individuals who have risk factors of COVID-19 infection.
    keywords: cancer; chemotherapy; clinical; covid-19; infection; japan; pandemic; patients; risk; s-1; treatment; trial
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        item: #1359 of 7819
          id: cord-265278-wf5pbvvt
      author: Fishman, Jay A.
       title: Case 29-2020: A 66-Year-Old Man with Fever and Shortness of Breath after Liver Transplantation
        date: 2020-09-17
       words: 5278
      flesch: 33
     summary: Clinical characteristics of coronavirus disease 2019 in China Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series A novel coronavirus from patients with pneumonia in China A novel coronavirus emerging in Chinakey questions for impact assessment Novel Coronavirus-19 (COVID-19) in the immunocompromised transplant recipient: #Flatten-ingthecurve Focus on Case Records of the Massachusetts Gener al Hospital COVID toes Clinical features of patients infected with 2019 novel coronavirus in Wuhan COVID-19 in solid organ transplant recipients: a single-center case series from Spain Co-infections of SARS-CoV-2 with multiple common respiratory pathogens in infected patients Rates of co-infection between SARS-CoV-2 and other respiratory pathogens The immunocompromised transplant recipient and SARS-CoV-2 infection Management of patients on dialysis and with kidney transplant during SARS-COV-2 (COVID-19) pandemic In Brescia SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS COVID-19 in solid organ transplant recipients: initial report from the US epicenter Covid-19 and kidney transplantation Open-SAFELY: factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients COVID-19 in solid organ transplant recipients: dynamics of disease progression and inflammatory markers in ICU and non-ICU admitted patients Multiorgan and renal tropism of SARS-CoV-2 Early description of coronavirus 2019 disease in kidney transplant recipients in New York Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases Clinical significance of human coronavirus in bronchoalveolar lavage samples from hematopoietic cell transplant recipients and patients with hematologic malignancies Prolonged shedding of human coronavirus in hematopoietic cell transplant recipients: risk factors and viral genome evolution The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: an analysis of all 1755 patients Viral shedding patterns of coronavirus in patients with probable severe acute respiratory syndrome Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Severe acute respiratory syndrome (SARS) in a liver transplant recipient and guidelines for donor SARS screening Emerging viral infections in transplant recipients MERS CoV infection in two renal transplant recipients: case report A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Communityacquired respiratory viruses in transplant patients: diversity, impact, unmet clinical needs Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia SARS-CoV-2 viral load in upper respiratory specimens of infected patients Epidemiology of SARS-CoV-2 emergence amidst community-acquired respiratory viruses Asymptomatic cases in a family cluster with SARS-CoV-2 infection Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility Diagnostic performance of CT and reverse transcriptase-polymerase chain reaction for coronavirus disease 2019: Research regarding the appropriate adjustment of exogenous immunosuppression for transplant patients, the timely start of antiviral therapies, and the deployment of antiinflammatory and immunomodulatory therapies in Covid-19 is in progress.
    keywords: acute; coronavirus; cov-2; covid-19; disease; infection; novel; organ; patients; recipients; renal; sars; transplant; transplantation
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        item: #1360 of 7819
          id: cord-265290-5txhcr7h
      author: Siso-Almirall, A.
       title: PROGNOSTIC FACTORS IN SPANISH COVID-19 PATIENTS: A CASE SERIES FROM BARCELONA
        date: 2020-06-20
       words: 1891
      flesch: 51
     summary: This study summarizes the clinical, biological and radiological characteristics, evolution and prognostic factors of patients with COVID-19 disease. A recent international consensus states that radiological assessment is not necessary in asymptomatic patients or those with mild disease but is required in patients with moderate or severe disease, regardless of whether a definite diagnosis of COVID-19 has been made [20] .
    keywords: 95%ci; covid-19; disease; patients
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        item: #1361 of 7819
          id: cord-265293-l9omunq4
      author: Schönegger, Carmen Maria
       title: Smell and Taste Disorders in COVID-19 Patients: Objective Testing and Magnetic Resonance Imaging in Five Cases
        date: 2020-10-24
       words: 2119
      flesch: 48
     summary: Nevertheless, controlled studies indicate that anosmia is more common in COVID-19 patients than in patients suffering from other viral infections or controls [17] . Hypothesis of neurotropism of SARS-CoV-2 is based on COVID-19 patients with neurological manifestations.
    keywords: covid-19; disease; olfactory; patients; smell; taste
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        item: #1362 of 7819
          id: cord-265309-1su480xi
      author: Bagdasarian, Natasha
       title: A safe and efficient, naturally ventilated structure for COVID-19 surge capacity in Singapore
        date: 2020-06-24
       words: 1215
      flesch: 44
     summary: Containment effectiveness of expedient patient isolation units Implementing a negative-pressure isolation ward for a surge in airborne infectious patients Proposed protocol to keep COVID-19 out of hospitals Environmental control measures for airborne infection isolation surge capacity planning in health care facilities for smallpox, SARS or other infections. This report demonstrates the potential for an adapted structure to provide rapid, safe and effective surge capacity for the triage, screening and management of COVID-19 patients.
    keywords: covid-19; emd; hospital; patients; structure
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        item: #1363 of 7819
          id: cord-265327-k00w7gmk
      author: Muraca, Maurizio
       title: Mesenchymal stromal cells and their secreted extracellular vesicles as therapeutic tools for COVID-19 pneumonia? (*)
        date: 2020-07-03
       words: 4322
      flesch: 31
     summary: Biology and potential therapeutic value Mesenchymal stem cells for acute lung injury: Preclinical evidence Mesenchymal Stem Cells and Acute Lung Injury Transplantation of allogeneic and xenogeneic placentaderived cells reduces bleomycin-induced lung fibrosis Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung Cytokine-targeted therapy in severely ill COVID-19 patients: Options and cautions Acute lung injury: How macrophages orchestrate resolution of inflammation and tissue repair Bone marrow stromal cells attenuate sepsis via prostaglandin E2-dependent reprogramming of host macrophages to increase their interleukin-10 production Mesenchymal stromal cells ameliorate acute lung injury induced by LPS mainly through stanniocalcin-2 mediating macrophage polarization Pathological findings of COVID-19 associated with acute respiratory distress syndrome Autopsy Findings and Venous Thromboembolism in Patients With COVID-19 What drives neutrophils to the alveoli in ARDS? MSCs are a heterogeneous population containing stromal cells, progenitor cells, fibroblasts and stem cells
    keywords: acute; cells; evs; lung; mesenchymal; msc; mscs; patients; stem
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        item: #1364 of 7819
          id: cord-265328-83p3sjja
      author: Limcaoco, R. S. G.
       title: Anxiety, worry and perceived stress in the world due to the COVID-19 pandemic, March 2020. Preliminary results.
        date: 2020-04-06
       words: 3502
      flesch: 50
     summary: However they maintain high stress levels for a longer time turning it into chronic stress. A possible explanation to this, is that this professionals are more accustomed to managing higher stress levels because of the nature of their jobs.
    keywords: covid-19; health; stress; study; survey; worry
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        item: #1365 of 7819
          id: cord-265340-hc9003dj
      author: Merzon, Eugene
       title: Low plasma 25(OH) vitamin D level is associated with increased risk of COVID‐19 infection: an Israeli population‐based study
        date: 2020-07-23
       words: 3130
      flesch: 38
     summary: Notably, a recent study from the UK (31-33) that included 449 subjects (from the UK Biobank) with confirmed COVID-19 infection did not find an association between vitamin D metabolite concentration and the risk of viral infections (45) as well as COVID-19 infection (5, 7, (9) (10) (11) (12) (13) (14) (15) 19, (30) (31) (32) (33) (34) (35) (36) (37) (38) (39) (40) (41) (42) 46) . In particular, the pronounced impact of vitamin D metabolites on the immune system response, and on the development of COVID-19 infection by the novel SARS CoV-2 virus, has been described (5) (6) (7) (8) (9) (10) (11) (12) (13) (14) (15) .
    keywords: article; copyright; covid-19; infection; plasma; risk; study; vitamin
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        item: #1366 of 7819
          id: cord-265343-4wfsze80
      author: Mhango, Malizgani
       title: COVID-19 Risk Factors Among Health Workers: A Rapid Review
        date: 2020-06-06
       words: 2360
      flesch: 49
     summary: A rapid review was carried out on 20 April 2020 on Covid-19 risk factors among HWs in PubMed, Google Scholar, and EBSCOHost Web (Academic Search Complete, CINAHL Complete, MEDLINE with Full Text, CINAHL with Full Text, APA PsycInfo, Health Source—Consumer Edition, Health Source: Nursing/Academic Edition) and WHO Global Database. In this study, we aimed to map available evidence on Covid-19 risk factors among HWs to guide future research and policy.
    keywords: covid-19; factors; health; hws; review; risk
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        item: #1367 of 7819
          id: cord-265346-vygvs1x3
      author: MOHAMED, N. A.
       title: EARLY VIRAL CLEARANCE AMONG COVID-19 PATIENTS WHEN GARGLING WITH POVIDONE-IODINE AND ESSENTIAL OILS: A PILOT CLINICAL TRIAL
        date: 2020-09-09
       words: 3383
      flesch: 55
     summary: This pilot, open labeled, randomized, parallel study compared the effect of 30 seconds, 3 times/day gargling using 1% povidone-iodine (PVP-I), essential oils and tap water on SARS-CoV-2 viral clearance among COVID-19 patients in a tertiary hospital in Kuala Lumpur. Therefore, we embarked on this preliminary study to look for the effect of gargling with PVP-I, essential oils, and tap water among COVID-19 patients on viral clearance.
    keywords: covid-19; gargling; oils; patients; preprint; pvp; study
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        item: #1368 of 7819
          id: cord-265370-mhy4nu7e
      author: KINI, GANESH
       title: All’s not well with the “worried well”: understanding health anxiety due to COVID-19
        date: 2020-10-06
       words: 1491
      flesch: 39
     summary: Neurologic manifestations of hospitalized patients with coronavirus disease COVID-19 and the cardiovascular system COVID-19: gastrointestinal manifestations and potential fecal-oral transmission Characteristics of ocular findings of patients with coronavirus disease 2019 (COVID-19 Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review The psychological impact of quarantine and how to reduce it: rapid review of the evidence COVID-19) infodemic and emerging issues through a data lens: the case of China Lifestyle behaviours during the COVID-19 -time to connect Facebook addiction and loneliness in the post-graduate students of a university in southern India Mental health problems and social media exposure during COVID-19 outbreak Understanding and treating health anxiety: A cognitivebehavioral approach COVID-19 pandemic -a focused review for clinicians Stability issues of RT-PCR testing of SARS-CoV-2 for hospitalized patients clinically diagnosed with COVID-19 Caution and clarity required in the use of chloroquine for COVID-19 Stigma reduction and provision of mental health services in the public health response to COV-ID-19 Internet-based cognitive-behavioural therapy for severe health anxiety: randomised controlled trial Funding sources: this research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. Individuals with health anxiety may get dismissed as the “worried well” in this pandemic due to disruption of mental health services and inability of healthcare systems to understand the psychosocial factors in the background.
    keywords: anxiety; covid-19; health; individuals; pandemic
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        item: #1369 of 7819
          id: cord-265372-vytmwmoj
      author: Shah, Nita H
       title: Control Strategies to Curtail Transmission of COVID-19
        date: 2020-04-07
       words: 2651
      flesch: 43
     summary: https://doi.org/10.1101/2020.04.04.20053173 doi: medRxiv preprint Figure 3 variation in all compartments Figure 3 represents the variations in all the compartments of COVID-19 model with respect to time. During the initial stages of COVID-19 outbreak, such human transmissions were taking place because, wide-range of public was unaware of these risk factors, and the infected individuals were also not isolated and were spreading the virus unknowingly to other individuals.
    keywords: control; covid-19; individuals; license; preprint
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        item: #1370 of 7819
          id: cord-265506-fxus6n65
      author: Westrupp, Elizabeth M.
       title: Study Protocol for the COVID-19 Pandemic Adjustment Survey (CPAS): A Longitudinal Study of Australian Parents of a Child 0–18 Years
        date: 2020-08-31
       words: 6704
      flesch: 49
     summary: Job loss, employment uncertainty, and difficulties in juggling work and family roles are associated with increases in parent mental health problems, couple conflict, and child mental health problems (8) (9) (10) (11) (12) (13) (14) (15) (16) . In Australia and other nations, child mental health problems are clustered in places of disadvantage (20) .
    keywords: australian; child; children; covid-19; family; health; item; pandemic; parents; participants; point; scale; study; survey; time
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        item: #1371 of 7819
          id: cord-265522-qutjr010
      author: Wei, Xiaowei
       title: Timely glucose monitoring-related potential risk of occupational exposure during the pandemic of COVID-19: A diabetologist's perspective
        date: 2020-05-06
       words: 505
      flesch: 33
     summary: With the application of FGM for glucose monitoring, nurses could monitor glucose intensively without considerable increase of occupational exposure to COVID-19. According to the therapeutic experience of Severe Acute Respiratory Syndrome, timely glucose monitoring and control may improve the prognosis of diabetes patients with coronavirus infection
    keywords: covid-19; glucose
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        item: #1372 of 7819
          id: cord-265530-hn7fi5cv
      author: Jansen, Danielle
       title: Child and adolescent health needs attention now, and in the aftermath of the COVID-19 pandemic
        date: 2020-08-01
       words: 1146
      flesch: 37
     summary: We differentiate child and adolescent public health into eight core public health priorities, all most probably affected by the pandemic (Children's Commisioner 2018): (1) injuries, (2) mental health (3) maltreatment, (4) risky behaviors, (5) nutrition in early life and prevention of childhood and adolescent obesity, (6) vaccination uptake, (7) access to health care, and (8) inequity in child development and learning. The CAPH directorate encourages public health researchers to investigate both beneficial and adverse effects of the COVID-19 pandemic and make use of the variety in COVID-19 policies and interventions for further understanding of measures and health consequences in the context of children and adolescents.
    keywords: care; children; covid-19; health
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        item: #1373 of 7819
          id: cord-265589-mn2wr79n
      author: buonsenso, d.
       title: Management of malaria in children under 5-years-old during COVID-19 pandemic in Sierra Leone: a lesson learned?
        date: 2020-11-05
       words: 2554
      flesch: 40
     summary: Also, ecological changes during the three study periods may have potentially influenced the trend of local malaria diagnoses, although currently there are no published evidences of unusually different rainy or dry seasons in the study period. According to local doctors and community health workers, in Sierra Leone health authorities and healthcare workers worked hard to ensure that people would not miss malaria care as happened during EVD outbreak.
    keywords: covid-19; health; license; malaria; preprint
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        item: #1374 of 7819
          id: cord-265596-o6jdvlya
      author: Pan, Lei
       title: Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study
        date: 2020-04-14
       words: 3565
      flesch: 42
     summary: In this study, we aimed to further investigate the prevalence and outcomes of COVID-19 patients with digestive symptoms. In this study, we enrolled patients confirmed to have COVID-19 from 3 hospitals in Hubei province and investigated the prevalence, clinical characteristics, and outcomes of COVID-19 patients with vs without digestive symptoms.
    keywords: covid-19; data; hospital; patients; study; symptoms; time
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        item: #1375 of 7819
          id: cord-265598-4h3wx81q
      author: Hasan, Abdulkarim
       title: Histopathology Laboratory Paperwork as a Potential Risk of COVID-19 Transmission among the Lab Personnel
        date: 2020-08-06
       words: 2230
      flesch: 42
     summary: We found that 80% of paper request forms reach the laboratory from other departments within 24hours, during this time the virus may remain viable. A Retrospective Cohort Study in a Designated Hospital of Wuhan in China Aerosol and Surface Distribution of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospital Wards The impact of automating laboratory request forms on the quality of healthcare services Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 Stability of SARS coronavirus in human specimens and environment and its sensitivity to heating and UV irradiation Survival of severe acute respiratory syndrome coronavirus A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
    keywords: covid-19; forms; laboratory; paper; risk; sars
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        item: #1376 of 7819
          id: cord-265603-3we40x62
      author: Casey, M.
       title: Estimating pre-symptomatic transmission of COVID-19: a secondary analysis using published data
        date: 2020-05-11
       words: 4495
      flesch: 42
     summary: Based on individual estimates, transmission time relative to symptom onset ranged from mean of 2.95 days before symptom onset to 1.72 days after symptom onset and proportion of pre-symptomatic transmission ranged from 33.7% to 79.9%. We subtracted incubation period from serial interval or generation time to infer transmission time relative to onset of symptoms and to estimate the proportion of pre-symptomatic transmission.
    keywords: interval; license; medrxiv; onset; preprint; time; transmission
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        item: #1377 of 7819
          id: cord-265610-om510pt7
      author: Cervantes‐Arslanian, Anna
       title: Rapid Dissemination of Protocols for Managing Neurology Inpatients with COVID‐19
        date: 2020-06-03
       words: 1704
      flesch: 32
     summary: Over a 2-week period, task force members developed management protocols according to their subspecialty expertise and uploaded them to a shared document. At our institution, we established a group of fifteen neurologists from six subspecialties that created protocols on managing inpatients with concurrent neurological disorders and COVID-19, using best available evidence and expert opinion.
    keywords: covid-19; dissemination; pandemic; protocols; visitors
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        item: #1378 of 7819
          id: cord-265721-wmz3wywi
      author: Saini, Kamal S.
       title: Repurposing anticancer drugs for COVID-19-induced inflammation, immune dysfunction, and coagulopathy
        date: 2020-06-22
       words: 1978
      flesch: 24
     summary: Small COVID-19 study shows encouraging results for EUSA Pharma Association of treatment dose anticoagulation with in-hospital survival among hospitalized patients with COVID-19 Corticosteroid treatment of patients with coronavirus disease 2019 (COVID-19) SARS-COV-2 infection in cancer patients undergoing checkpoint blockade: clinical course and outcome COVID-19: risk for cytokine targeting in chronic inflammatory diseases? COVID-19 Treatment Guidelines Panel. In classic, cis-mediated signalling IL-6 binds to its membrane-bound receptor mIL-6R that is present on immune cells and modulates Janus kinases (JAKs) and signal transducer and activator of transcription 3 (STAT3); in trans-mediated signalling IL-6 binds to its soluble receptor sIL-6R, potentially impacting all cell surfaces; while in trans-mediated presentation, IL-6 binds to mIL-6R on immune cells leading to downstream T cell signalling precipitating acute respiratory distress syndrome.
    keywords: cancer; cells; covid-19; il-6; inflammation; patients; roche; treatment
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        item: #1379 of 7819
          id: cord-265779-p2bro1ai
      author: Hussein, Nawfal R.
       title: Impact Of Covid-19 Pandemic On Surgical Practice In Kurdistan, Iraq: An Online Cross-Sectional Survey
        date: 2020-11-04
       words: 2607
      flesch: 53
     summary: In addition, local authorities in the Kurdistan region of Iraq diverted the city's limited staff and resources to cater to COVID-19 patients [6, 7] . Participants were then asked for specific questions about the use of personal protection, number of surgeries performed during COVID-19, and motivation of the surgeon to work in the management and treatment of COVID-19 patients.
    keywords: covid-19; iraq; kurdistan; pandemic; region; surgeons
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        item: #1380 of 7819
          id: cord-265799-qda5awuc
      author: Carothers, Chancey
       title: Acetylcysteine for the Treatment of Suspected Remdesivir‐Associated Acute Liver Failure in COVID‐19: A Case Series
        date: 2020-10-02
       words: 3158
      flesch: 42
     summary: 15 In these cases, however, severe liver injury was usually associated with several months of tocilizumab therapy, where our patient only received a single dose prior to ALF. Drug-induced liver injury (DILI) is a serious adverse effect of medications that can range in presentation from mild transaminitis to fulminant liver failure and represents one of the most common causes of acute liver failure. By day on remdesivir, with a 200 mg IV loading dose and 100 mg IV daily for the next 4 days (finishing on hospital day 9).
    keywords: acetylcysteine; alf; day; liver; patient; remdesivir; use
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        item: #1381 of 7819
          id: cord-265813-2onv9mvl
      author: Criado, Paulo Ricardo
       title: Are the cutaneous manifestations during or due to SARS-CoV-2 infection/COVID-19 frequent or not? Revision of possible pathophysiologic mechanisms
        date: 2020-06-02
       words: 5154
      flesch: 33
     summary: Probably due to lack of adequate personal protective equipment (PPE) for frontline health care workers, including respirators, face shields, gloves, ocular glasses, gowns, and hand sanitizers, dermatologists have not adequately registered the cutaneous findings in COVID-19 patients [18] . Other possibilities in developing ischemic/coagulopathy lesions as livedo racemosa, retiform purpura, and acroischemia in COVID-19 patients, besides activation of coagulation system [11] due to viral load, it is the presence in some subjects in selected populations with a background of thrombophilia factors.
    keywords: ace2; cell; coronavirus; cov-2; covid-19; disease; human; infection; manifestations; patients; protein; sars; skin; syndrome; tmprss2
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        item: #1382 of 7819
          id: cord-265833-vj5nrip6
      author: Coates, P Toby
       title: The Forgotten Fallen: painful reality of a pandemic
        date: 2020-06-15
       words: 395
      flesch: 29
     summary: Kidney international Cost-Related Medication Nonadherence in Adults With Atherosclerotic Cardiovascular Disease in the United States Economic Evaluation of Extending Medicare Immunosuppressive Drug Coverage for Kidney Transplant Recipients in the Current Era Éditions Gallimard key: cord-265833-vj5nrip6 authors: Coates, P Toby; Wong, Germaine title: The Forgotten Fallen: painful reality of a pandemic date: 2020-06-15 journal: Kidney Int DOI: 10.1016/j.kint.2020.06.002 sha: doc_id: 265833 cord_uid: vj5nrip6 nan When COVID-19 became a global pandemic, health professionals were particularly concerned of the potential risk it might impose on the most vulnerable groups, including our kidney and kidney pancreas transplant recipients.
    keywords: covid-19; kidney
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        item: #1383 of 7819
          id: cord-265855-zf52vl11
      author: Mayor-Ibarguren, Ander
       title: A Hypothesis for the Possible Role of Zinc in the Immunological Pathways Related to COVID-19 Infection
        date: 2020-07-10
       words: 5330
      flesch: 38
     summary: However, although plasma zinc concentration moderately correlates to habitual intake, the test also has limited specificity because zinc levels are depressed during inflammatory disease states or pregnancy and increase with acute catabolic states (42) . In severe infectious diseases, CRP levels can reach 100-200 mg/L, with a much greater decrease in zinc levels (40-60%) (43) .
    keywords: activation; covid-19; deficiency; disease; il-6; infection; levels; plasma; protein; response; rna; sars; treatment; zinc
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        item: #1384 of 7819
          id: cord-265877-dund6unq
      author: Yang, Q.
       title: Incidence and risk factors of kidney impairment on patients with COVID-19: a systematic review and meta-analysis
        date: 2020-06-03
       words: 3764
      flesch: 44
     summary: https://doi.org/10.1101/2020.05.28.20116400 doi: medRxiv preprint COVID-19 patients. Secondly, we found that the high statistic heterogeneity in the prevalence of kidney injury analysis.
    keywords: covid-19; kidney; license; medrxiv; patients; preprint; sars; version
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        item: #1385 of 7819
          id: cord-265890-quacalt5
      author: Arauzo-Carod, Josep-Maria
       title: A first insight about spatial dimension of COVID-19: analysis at municipality level
        date: 2020-08-18
       words: 2818
      flesch: 38
     summary: This paper has summarized the evolution of the first 21 weeks of the COVID-19 disease in Catalonia (Spain) through local spatial autocorrelation measures. Figure 3 shows local spatial autocorrelation data for the whole period.
    keywords: areas; cases; covid-19; public; spatial
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        item: #1386 of 7819
          id: cord-265899-skpkuzyu
      author: Pryzdial, Edward L. G.
       title: Antiviral anticoagulation
        date: 2020-07-06
       words: 5669
      flesch: 22
     summary: While numerous factors may contribute to a reduced platelet count in virus infection, 35 thrombocytopenia is usually attributed to enhanced thrombin production with consequent platelet activation and subsequent senescence. gC is a multifunctional contributor to virus infection known to participate in virus attachment to the cell through association with heparan sulfate proteoglycan and in the evasion of host defense by complement.
    keywords: cell; coagulation; covid-19; disease; envelope; factor; fxa; herpes; hsv1; infection; patients; sars; thrombin; tissue; virus
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        item: #1387 of 7819
          id: cord-265934-wjdxqj8h
      author: Singh, Amrita K.
       title: A Review of Telemedicine Applications in Otorhinolaryngology: Considerations During the Coronavirus Disease of 2019 Pandemic
        date: 2020-10-01
       words: 4197
      flesch: 33
     summary: A retrospective analysis The value of CT scans in improving laryngoscopy in patients with laryngeal cancer Ultrasound imaging of the larynx and vocal folds: recent applications and developments Usefulness of ultrasonography in assessment of laryngeal carcinoma Laryngeal ultrasound as effective as CT scans for the diagnosis of various laryngeal lesions Telemedicine in laryngology: remote evaluation of voice disorders-setup and initial experience COVID-19 and rhinology: a look at the future Diagnostic accuracy of nasal endoscopy as compared to computed tomography in chronic Rhinosinusitis Comparative study of diagnostic nasal endoscopy and CT paranasal sinuses in diagnosing chronic rhinosinusitis endoscope-i: an innovation in mobile endoscopic technology transforming the delivery of patient care in otolaryngology Development of a microportable imaging system for otoscopy and nasoendoscopy evaluations Developing a synchronous otolaryngology telemedicine clinic: prospective study to assess fidelity and diagnostic concordance Utilization of a novel interactive mobile health platform to evaluate functional outcomes and pain following septoplasty and functional endoscopic sinus surgery change management in allergic rhinitis and asthma multimorbidity using mobile technology The Alaska experience using storeand-forward telemedicine for ENT care in Alaska Factors influencing patient satisfaction in plastic surgery: a Nationwide analysis Validation of videoconference with smartphones in telemedicine facial trauma care: analysis of concordance to on-site evaluation Telehealth in plastic surgery: a veterans affairs hospital perspective Patient satisfaction with an early smartphone-based cosmetic surgery postoperative follow-up Using telemedicine in otolaryngology Realtime telemedicine for paediatric ENT pre-admission screening Concordance between realtime telemedicine assessments and face-to-face consultations in paediatric otolaryngology Search terms were designed to identify studies which examined telemedicine use within ORL.
    keywords: care; evaluation; head; orl; patients; practice; study; surgery; telehealth; telemedicine; use
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        item: #1388 of 7819
          id: cord-266010-ectnfv5z
      author: Pediconi, Federica
       title: Breast imaging and cancer diagnosis during the COVID-19 pandemic: recommendations from the Italian College of Breast Radiologists by SIRM
        date: 2020-07-13
       words: 2739
      flesch: 32
     summary: The COVID-19 pandemic breast cancer consortium Recommendations for triage, prioritization and treatment of breast cancer patients during the COVID-19 pandemic Time to surgery and breast cancer survival in the United States Preoperative delays in the treatment of DCIS and the associated incidence of invasive breast cancer Oncology practice during the COVID-19 pandemic Managing cancer care during the COVID-19 pandemic: agility and collaboration toward a common goal Mammography screening reduces rates of advanced and fatal breast cancers: results in 549,091 women Association of screening and treatment with breast cancer mortality by molecular subtype in US women Breast cancer screening programs: does one risk fit all? Breast ultrasound: recommendations for information to women and referring physicians by the Diagnostic performance of MRI versus galactography in women with pathologic nipple discharge: a systematic review and meta-analysis Nipple discharge: the state of the art Breast MRI: EUSOBI recommendations for women's information Image-guided breast biopsy and localisation: recommendations for information to women and referring physicians by the European Society of Breast Imaging Solving the preoperative breast MRI conundrum: design and protocol of the MIPA study 4th ESO-ESMO international consensus guidelines for advanced breast cancer Mammography: an update of the EUSOBI recommendations on information for women The requirements of a specialist breast centre Loneliness and social isolation as risk factors for mortality Depression in cancer: the many biobehavioral pathways driving tumor progression Emotional distress, brain functioning, and biobehavioral processes in cancer patients: a neuroimaging review and future directions Acknowledgments Open access funding provided by Università degli Studi di Milano within the CRUI-CARE Agreement. key: cord-266010-ectnfv5z authors: Pediconi, Federica; Galati, Francesca; Bernardi, Daniela; Belli, Paolo; Brancato, Beniamino; Calabrese, Massimo; Camera, Lucia; Carbonaro, Luca A.; Caumo, Francesca; Clauser, Paola; Girardi, Veronica; Iacconi, Chiara; Martincich, Laura; Panizza, Pietro; Petrillo, Antonella; Schiaffino, Simone; Tagliafico, Alberto; Trimboli, Rubina M.; Zuiani, Chiara; Sardanelli, Francesco; Montemezzi, Stefania title: Breast imaging and cancer diagnosis during the COVID-19 pandemic: recommendations from the Italian College of Breast Radiologists by SIRM date: 2020-07-13 journal: Radiol Med DOI: 10.1007/s11547-020-01254-3 sha: doc_id: 266010 cord_uid: ectnfv5z The Italian College of Breast Radiologists by the Italian Society of Medical Radiology (SIRM) provides recommendations for breast care provision and procedural prioritization during COVID-19 pandemic, being aware that medical decisions must be currently taken balancing patient’s individual and community safety: (1) patients having a scheduled or to-be-scheduled appointment for in-depth diagnostic breast imaging or needle biopsy should confirm the appointment or obtain a new one; (2) patients who have suspicious symptoms of breast cancer (in particular: new onset palpable nodule; skin or nipple retraction; orange peel skin; unilateral secretion from the nipple) should request non-deferrable tests at radiology services; (3) asymptomatic women performing annual mammographic follow-up after breast cancer treatment should preferably schedule the appointment within 1 year and 3 months from the previous check, compatibly with the local organizational conditions; (4) asymptomatic women who have not responded to the invitation for screening mammography after the onset of the pandemic or have been informed of the suspension of the screening activity should schedule the check preferably within 3 months from the date of the not performed check, compatibly with local organizational conditions.
    keywords: breast; cancer; covid-19; imaging; pandemic; patients; recommendations
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        item: #1389 of 7819
          id: cord-266020-ngqfwyj4
      author: Taito, S.
       title: Assessment of the Publication Trends of COVID-19 Systematic Reviews and Randomized Controlled Trials
        date: 2020-09-01
       words: 1345
      flesch: 51
     summary: https://doi.org/10.1101/2020.08.27.20182956 doi: medRxiv preprint The figure shows the trend in the number of publications of systematic reviews (including systematic reviews and meta-analyses) and randomized controlled trials for COVID-19. Number of medRxiv systematic reviews and randomized controlled trials for COVID-19 (January to June 2020).
    keywords: medrxiv; preprint
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        item: #1390 of 7819
          id: cord-266031-tlrsco40
      author: Haghani, Milad
       title: Covid-19 pandemic and the unprecedented mobilisation of scholarly efforts prompted by a health crisis: Scientometric comparisons across SARS, MERS and 2019-nCoV literature
        date: 2020-09-21
       words: 8002
      flesch: 43
     summary: Covid-19 studies seem to have been disseminated across a broader variety of journals and across a more diverse range of subject areas. Covid-19 studies also display the involvement of authors from a broader variety of countries compared to SARS and MERS.
    keywords: cluster; coronavirus; covid-19; items; journal; literature; mers; number; publications; research; sars; studies
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        item: #1391 of 7819
          id: cord-266051-my2wj1uu
      author: Sheridan Rains, Luke
       title: Early impacts of the COVID-19 pandemic on mental health care and on people with mental health conditions: framework synthesis of international experiences and responses
        date: 2020-08-17
       words: 6536
      flesch: 38
     summary: Various adaptations and innovations to enable mental health services to respond to new requirements have been discussed, including infection control strategies on mental health service premises, and remote working [9, 10] . Specifically, we sought to analyse reports regarding: • direct impacts of COVID-19, subsequent public health measures and sudden social changes on people with preexisting mental health conditions and their families; • self-help and informal help strategies utilised by service users and carers; • challenges faced by mental health services during the pandemic; • innovations and adaptations to mitigate impacts of COVID-19 on mental health services, and reports regarding their effectiveness.
    keywords: care; covid-19; health; impacts; infection; mental; pandemic; people; problems; reports; service; sources; use
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        item: #1392 of 7819
          id: cord-266052-rcuzi70u
      author: Liu, Lilong
       title: Pit latrines may be a potential risk in rural China and low-income countries when dealing with COVID-19
        date: 2020-10-29
       words: 5752
      flesch: 28
     summary: Given that the infectious SARS-CoV-2 was found to be secreted through the human urinary system (Sun et al., 2020) and intestinal tract (Wang et al., 2020d; Xiao et al., 2020b; Zhou et al., 2020a) , and SARS-CoV-2 RNA was detected in wastewater worldwide (Randazzo et al., 2020), many studies have suggested the possibility of wastewater transmission of COVID-19 disease (Adelodun et al., 2020; Arslan et al., 2020; Foladori et al., 2020) . In addition, recent studies showed that human angiotensin-converting enzyme II (ACE2), which had been proved to be a cell receptor for SARS- CoV-2 (Lu et al., 2020; Zhou et al., 2020b) , was highly expressed in glandular cells of human gastric, duodenal, and rectal epithelia, supporting the entry of SARS-CoV-2 into host cells (Xiao et al., 2020a) .
    keywords: china; coronavirus; cov-2; covid-19; et al; excreta; human; latrines; patients; pit; potential; sars; water
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        item: #1393 of 7819
          id: cord-266055-ki4gkoc8
      author: Kikkisetti, S.
       title: Deep-learning convolutional neural networks with transfer learning accurately classify COVID19 lung infection on portable chest radiographs
        date: 2020-09-02
       words: 3436
      flesch: 45
     summary: While there are already many papers describing prevalence and radiographic features on pCXR of COVID-19 lung infection (see reviews (25, 26) ), there is a few peer-reviewed AI papers (27-32) and non-peer reviewed papers (33-36) to classify CXRs of COVID-19 patients from CXR of normals or related lung infections. CNN accurately classified COVID-19 pCXR from those of normal, bacterial pneumonia, and non-COVID-19 viral pneumonia patients in a multiclass model.
    keywords: covid-19; learning; medrxiv; pcxr; peer; pneumonia; preprint
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        item: #1394 of 7819
          id: cord-266070-28a85p50
      author: Oberhammer, J.
       title: Social-distancing effectiveness tracking of the COVID-19 hotspot Stockholm
        date: 2020-07-02
       words: 3330
      flesch: 41
     summary: Methods: A novel distributed-compartmental, time-variant epidemiological model was designed specifically for COVID-19 transmission characteristics, featuring a/pre/symptomatic transmission, a non-linear hospital model, a weakly-coupled sub-model for the care-home population, and parametrized continuous social-distancing functions. 28 Methods A novel distributed-compartmental, time-variant epidemiological model was designed 29 specifically for COVID-19 transmission characteristics, featuring a/pre/symptomatic transmission, a 30 non-linear hospital model, a weakly-coupled sub-model for the care-home population, and 31 parametrized continuous social-distancing functions.
    keywords: care; covid-19; license; medrxiv; model; population; preprint; transmission
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        item: #1395 of 7819
          id: cord-266079-nv28ppft
      author: Dai, Jinghong
       title: Corticosteroid treatment in severe COVID-19 pneumonia: two cases and literature review
        date: 2020-05-25
       words: 2391
      flesch: 38
     summary: Ann Rheum Dis:annrheumdis-2020-217523 Use of tocilizumab for COVID-19 infection-induced cytokine release syndrome: a cautionary case report Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Tcell immunity of SARS-CoV: implications for vaccine development against MERS-CoV Middle East respiratory syndrome coronavirus efficiently infects human primary T lymphocytes and activates the extrinsic and intrinsic apoptosis pathways Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients First case of 2019 novel coronavirus in the United States Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Authors' contributions Jinghong Dai, Yajun Qian, and Hui Li were the patient's internal medicine physicians. the Guangzhou experience National Influenza Apdm09 Clinical Investigation Group of C (2017) Effect of low-to-moderate-dose corticosteroids on mortality of hospitalized adolescents and adults with influenza A(H1N1)pdm09 viral pneumonia Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Pathological findings of COVID-19 associated with acute respiratory distress syndrome Thoughts and practice on the treatment of severe and critical new coronavirus pneumonia COVID-19: a new virus, but a familiar receptor and cytokine release syndrome Prognostic value of interleukin-6, C-reactive protein, and procalcitonin in patients with COVID-19 Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies Effective treatment of severe COVID-19 patients with tocilizumab Antirheumatic agents in covid-19: is IL-6 the right target?
    keywords: corticosteroids; covid-19; hrct; patients; pneumonia; treatment; use
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        item: #1396 of 7819
          id: cord-266088-485m5ped
      author: Cénat, Jude Mary
       title: Social inequalities and collateral damages of the COVID-19 pandemic: when basic needs challenge mental health care
        date: 2020-07-10
       words: 1280
      flesch: 43
     summary: In the meantime, mental health programs must be integrative and ecosystemic, addressing both basic needs and mental health issues, because when basic needs challenge psychosocial well-being, no matter how urgent it is, mental health care will wait. key: cord-266088-485m5ped authors: Cénat, Jude Mary; Dalexis, Rose Darly; Kokou-Kpolou, Cyrille Kossigan; Mukunzi, Joana N.; Rousseau, Cécile title: Social inequalities and collateral damages of the COVID-19 pandemic: when basic needs challenge mental health care date: 2020-07-10 journal: Int J Public Health DOI: 10.1007/s00038-020-01426-y sha: doc_id: 266088 cord_uid: 485m5ped nan Never before has there been such a high level of mobilization around mental health during an epidemic (Pappa et al. 2020) .
    keywords: covid-19; health; needs
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        item: #1397 of 7819
          id: cord-266113-3fp46sov
      author: Dashti‐Khavidaki, Simin
       title: Considerations for Statin Therapy in Patients with COVID‐19
        date: 2020-05-04
       words: 1357
      flesch: 31
     summary: SARS-CoV-2 is the third coronavirus outbreak during the current century after severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) coronaviruses.1 Acute respiratory distress syndrome (ARDS) is an immunopathologic event and main cause of death following COVID-19. SARS-CoV-2 is the third coronavirus outbreak during the current century, after the outbreaks of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) coronaviruses.
    keywords: acute; covid-19; patients; sars
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        item: #1398 of 7819
          id: cord-266118-jjzr4yn3
      author: Jing, Zhi-Cheng
       title: Recommendations from the Peking Union Medical College Hospital for the management of acute myocardial infarction during the COVID-19 outbreak
        date: 2020-03-31
       words: 1214
      flesch: 35
     summary: a. Consult specialists on infectious diseases or respiratory physicians from designated medical institutions to confirm COVID-19 as soon as possible. If COVID-19 cannot be excluded by chest CT, routine medical treatment of NSTEMI should be given and risk stratification Cardiopulse should be conducted while waiting for the results of nucleic acid detection.
    keywords: covid-19; medical; patients; treatment
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        item: #1399 of 7819
          id: cord-266120-bcya8jrs
      author: D'Ascanio, Luca
       title: Letter to the editor regarding “corona-steps for tracheotomy in codid-19 patients: a staff-safe method for airway management”
        date: 2020-04-20
       words: 822
      flesch: 33
     summary: As to open the trachea item, basing on our experience on 22 Caucasian patients (19M, 3F), mean age 67 years (age range: 47-74), submitted to surgical tracheostomy between February 3 rd and March 14 th 2020, after a long (mean: 21.54+/-2.11 days) orotracheal intubation for sever acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia, we suggest the following tips: (1) Pichi et al push the tube as caudally as possible before opening the trachea (intraoperatively). We quantified this contamination risk by measuring AET during our procedures: AET for surgical tracheostomy was 5.5+1.4 seconds (range: 4-9 seconds), significantly (p<0.001) inferior to AET for percutaneous tracheotomy (21.8+5.7 seconds).
    keywords: hcws; patients; tracheostomy
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        item: #1400 of 7819
          id: cord-266132-i57avso9
      author: Kirksey, Lee
       title: Pandemic Superimposed on Epidemic: Covid-19 Disparities in Black Americans
        date: 2020-08-01
       words: 1992
      flesch: 37
     summary: Accurate public reporting of tests administered, confirmed positive results and patient outcomes for Blacks will allow strategic planning and public health efforts to be effectively and equitably deployed and implemented. Defying public health recommendations during the COVID-19 pandemic, where physical distancing has been mandated legislatively is not an option for these essential worker groups.
    keywords: covid-19; health; healthcare; population; public; testing
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        item: #1401 of 7819
          id: cord-266145-xnu8pj24
      author: Ahmed, Mohammed A. M.
       title: COVID-19 in Somalia: Adherence to Preventive Measures and Evolution of the Disease Burden
        date: 2020-09-06
       words: 3289
      flesch: 43
     summary: Two consecutive cross-sectional surveys investigating the adherence to COVID-19 preventive measures were conducted. A multivariable model investigating factors associated with the adherence score to COVID-19 preventive measures found that being a female, healthcare worker/student, and obtaining COVID-19 information from official sources significantly increased the odds for higher adherence (Table 7 ).
    keywords: adherence; covid-19; masks; measures; somalia; study; survey
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        item: #1402 of 7819
          id: cord-266150-wox7pnkr
      author: Torres, Juan Pablo
       title: SARS-CoV-2 antibody prevalence in blood in a large school community subject to a Covid-19 outbreak: a cross-sectional study
        date: 2020-07-10
       words: 4206
      flesch: 46
     summary: The median percent of antibody positive students per classroom was 8.3% (IQR 1.6-14.3%). Certainly, school related outbreak studies from other settings and situations, especially after the first wave, are required to further increase our knowledge of transmission dynamics within M a n u s c r i p t 10 schools, in order to pinpoint recommendations which may end up being most effective.
    keywords: antibody; cases; children; covid-19; outbreak; positivity; school; staff; students; test
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        item: #1403 of 7819
          id: cord-266160-464v4g8o
      author: Bajaj, Jasmohan S
       title: Comparison of mortality risk in patients with cirrhosis and COVID-19 compared with patients with cirrhosis alone and COVID-19 alone: multicentre matched cohort
        date: 2020-07-13
       words: 3696
      flesch: 44
     summary: A new method of classifying prognostic comorbidity in longitudinal studies: development and validation Survival in infection-related acute-on-chronic liver failure is defined by extrahepatic organ failures One world, one pandemic, many guidelines: management of liver diseases during COVID-19 Declining cirrhosis hospitalizations in the wake of the COVID-19 pandemic: a national cohort study Diagnosing and treating renal disease in cirrhotic patients Covid-19 and acute kidney injury in hospital: summary of NICE guidelines Functional decline in patients with cirrhosis awaiting liver transplantation: results from the functional assessment in liver transplantation (FrAILT) study Clinical course of acute-on-chronic liver failure syndrome and effects on prognosis Model for end-stage liver Disease-Lactate and prediction of inpatient mortality in patients with chronic liver disease Novelty in the gut: a systematic review and meta-analysis of the gastrointestinal manifestations of COVID-19 Gastrointestinal symptoms in patients with liver cirrhosis: associations with nutritional status and health-related quality of life We're not all in this together: on COVID-19, intersectionality, and structural inequality COVID-19: abnormal liver function tests Patient and public involvement Patients and/or the public were not involved in the design, conduct, reporting or dissemination plans of this research. Covid-19 in Critically Ill Patients in the Seattle Region -Case Series People of any age with underlying medical conditions Clinical course and risk factors for mortality of COVID-19 patients with pre-existing cirrhosis: a multicentre cohort study High mortality rates for SARS-CoV-2 infection in patients with pre-existing chronic liver disease and cirrhosis: Preliminary results from an international registry COVID-19 in solid organ transplant recipients: initial report from the US EpiCenter Clinical characteristics and outcomes of COVID-19 among patients with pre-existing liver disease in United States: a multi-center research network study NACSELD acute-on-chronic liver failure (NACSELD-ACLF) score predicts 30-day survival in hospitalized patients with cirrhosis Acute-On-Chronic liver failure: getting ready for prime time?
    keywords: cirrhosis; cirrhosis+covid-19; covid-19; group; liver; mortality; patients
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        item: #1404 of 7819
          id: cord-266175-4jyltfus
      author: Brendish, Nathan J
       title: Clinical impact of molecular point-of-care testing for suspected COVID-19 in hospital (COV-19POC): a prospective, interventional, non-randomised, controlled study
        date: 2020-10-08
       words: 5487
      flesch: 39
     summary: In addition to testing symptomatic acute admissions to hospital, point-of-care testing could also be used for assessing elective hospital admissions, primary care patients, hospital staff, and care home staff and residents, as well as for airport screening, school screening, and even population-level screening. Initially, laboratory PCR testing used the PHE RdRp gene assay alone and subsequently used the PHE RdRp and E gene assays combined.
    keywords: care; care testing; cov-2; covid-19; group; patients; point; respiratory; sars; study; testing
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        item: #1405 of 7819
          id: cord-266183-uzuda3ir
      author: Renieris, Georgios
       title: Serum Hydrogen Sulfide and Outcome Association in Pneumonia by the SARS-CoV-2 Corona virus
        date: 2020-05-18
       words: 2212
      flesch: 43
     summary: A novel coronavirus from patients with pneumonia in China Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The perspectives of clinical immunologists from China CII: Pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors Hydrogen sulfide signaling in mitochondria and disease Sulfur compounds block MCP-1 production by Mycoplasma fermentans-infected macrophages through NF-κB inhibition Hydrogen sulfide attenuates atherosclerosis in a partially ligated carotid artery mouse model via regulating angiotensin converting enzyme 2 expression Survival predictors in elderly patients with acute respiratory distress syndrome: a prospective observational cohort study Pneumonia severity index in viral community acquired pneumonia in adults Unauthorized reproduction of this article is prohibited Analysis of endogenous H2S and H2Sn in mouse brain by high-performance liquid chromatography with fluorescence and tandem mass spectrometric detection Measurement of plasma hydrogen sulfide in vivo and in vitro Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirusinfected pneumonia in Wuhan The role of H2S bioavailability in endothelial dysfunction The assessment of endothelial function: from research into clinical practice Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan The cytokine release syndrome (CRS) of severe COVID-19 and Interleukin-6 receptor (IL-6R) antagonist tocilizumab may be the key to reduce the mortality Inhaled Hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice We furtherinvestigated the association between over-time change of serum H2S and outcome.
    keywords: covid-19; day; h2s; outcome; patients; pneumonia; serum
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        item: #1406 of 7819
          id: cord-266209-gvvc8wqe
      author: Xiao, Lu-shan
       title: Development and Validation of a Deep Learning-Based Model Using Computed Tomography Imaging for Predicting Disease Severity of Coronavirus Disease 2019
        date: 2020-07-31
       words: 5461
      flesch: 44
     summary: According to recent literature, the mortality rate for severe COVID-19 patients is approximately 20 times higher than that for non-severe COVID-19 patients (Chen N. et al., 2020; Gong et al., 2020; Yang et al., 2020) . Our deep learning-based model can accurately predict disease severity as well as disease progression in COVID-19 patients using CT imaging, offering promise for guiding clinical treatment.
    keywords: covid-19; data; disease; honghu; learning; model; patients; risk; severity
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        item: #1407 of 7819
          id: cord-266214-l8pmhcd5
      author: Wang, Xiaogang
       title: Management Strategies for Patients After CABG Surgery in the Outbreak of the COVID-19 Pandemic
        date: 2020-09-21
       words: 2642
      flesch: 40
     summary: key: cord-266214-l8pmhcd5 authors: Wang, Xiaogang; Zhou, Yangzhao; Zhang, Xia; Li, Jianming; Zhou, Xinmin; Zhang, ZhiWei title: Management Strategies for Patients After CABG Surgery in the Outbreak of the COVID-19 Pandemic date: 2020-09-21 journal: Risk Manag Healthc Policy DOI: 10.2147/rmhp.s271133 sha: doc_id: 266214 cord_uid: l8pmhcd5 BACKGROUND: Patients with pre-existing cardiovascular disease may have a higher risk of infection of COVID-19 and worse outcomes than others.
    keywords: cabg; covid-19; disease; health; infection; patients; risk
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        item: #1408 of 7819
          id: cord-266220-78g951x4
      author: Palazzani, Laura
       title: The pandemic and the ethical dilemma of limited resources: who to treat?
        date: 2020-09-24
       words: 3589
      flesch: 32
     summary: The issue of the distribution of health resources is certainly not a new topic in bioethics. In this perspective, the right to access treatment and health care is recognised only to those who have a life worthy of being lived in relation to the achievement or likelihood of achieving an expected number of years of life left to live and a certain standard of quality of life 3 .
    keywords: access; care; covid-19; distribution; health; pandemic; resources
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        item: #1409 of 7819
          id: cord-266234-lg866rnt
      author: Adrogué, A. H.
       title: A kidney transplant recipient with COVID-19: utility of a prognostication score
        date: 2020-09-03
       words: 2117
      flesch: 51
     summary: What is not clear is whether IS increases mortality in COVID-19 patients. Conclusion Since this is only a single case, we plan to retrospectively review a series of patients to validate our initial experience: that a low H-Score may correlate with a milder hospital course in kidney transplant patients with COVID-19.
    keywords: covid-19; patients; rhlh; score; transplant
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        item: #1410 of 7819
          id: cord-266238-922ncaay
      author: Xiang, Mi
       title: Impact of COVID-19 pandemic on children and adolescents' lifestyle behavior larger than expected
        date: 2020-04-30
       words: 439
      flesch: 38
     summary: Global recommendations on physical activity for health Global trends in insufficient physical Journal Pre-proof adolescents: a pooled analysis of 298 population-based surveys with 1·6 million participants A tale of two pandemics: How will COVID-19 and global trends in physical inactivity and sedentary behavior affect one another? Thus, a better understanding of the current situation of PA and SB during this pandemic among children and adolescents could help teachers, parents, and the Ministry of Education to urgently determine and implement effective policies and interventions for children and adolescents.
    keywords: adolescents; children
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        item: #1411 of 7819
          id: cord-266242-d4fo3lsn
      author: Ostapenko, A.
       title: Impacts on Surgery Resident Education at a first wave COVID-19 epicenter
        date: 2020-08-18
       words: 3084
      flesch: 40
     summary: Methods: We conducted an observational study at a Western Connecticut hospital heavily affected by the first wave of the COVID-19 pandemic to assess its effects on surgical residents, focusing on surgical education, clinical experience, and operative skills development. 1, 2, 3 Examples of this include the cancellation of non-emergent operations, the transition of various sectors to Telehealth medicine, and the redistribution of surgical residents to non-surgical services.
    keywords: covid-19; license; pandemic; preprint; residents
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        item: #1412 of 7819
          id: cord-266257-hp11at50
      author: Zhang, Yao
       title: Mental Health Problems during the COVID-19 Pandemics and the Mitigation Effects of Exercise: A Longitudinal Study of College Students in China
        date: 2020-05-25
       words: 5417
      flesch: 42
     summary: In addition, our study advances a suitable range of physical activity to maintain psychological health of 108 min of light, 80 min of moderate, or 45 min of vigorous physical activity daily, which we recommended for psychological interventions during the COVID-19 period. Total minutes of vigorous physical activity in the last week were constructed based on two questions: During the last seven days, how many days did you spend on vigorous physical activities like lifting, fast cycling, and fast swimming?
    keywords: activity; covid-19; death; emotions; health; outbreak; quality; sleep; study
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        item: #1413 of 7819
          id: cord-266283-xnzdkxm3
      author: Wakfie-Corieh, Cristina Gamila
       title: Assessment of extra-parenchymal lung involvement in asymptomatic cancer patients with COVID-19 pneumonia detected on (18)F-FDG PET-CT studies
        date: 2020-09-08
       words: 4507
      flesch: 41
     summary: Although this image modality is not routinely used in the management of COVID-19 patients, it could contribute to give complementary information to other laboratory and radiological data in selected cases. In contrast, patients in the control group exhibited bilateral infiltrates Extra-parenchymal lung findings were found in 42.9% (6/14) of confirmed COVID-19 patients (Fig. 2) .
    keywords: cancer; coronavirus; covid-19; fdg; findings; lung; patients; pet; pneumonia; study; uptake
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        item: #1414 of 7819
          id: cord-266293-lqag2p3u
      author: González-Olmo, María José
       title: Oral hygiene habits and possible transmission of COVID-19 among cohabitants
        date: 2020-10-19
       words: 3641
      flesch: 46
     summary: We found significant differences in oral hygiene measures for tongue brushing (t = 2.202; p = 0.029*). key: cord-266293-lqag2p3u authors: González-Olmo, María José; Delgado-Ramos, Bendición; Ruiz-Guillén, Ana; Romero-Maroto, Martín; Carrillo-Díaz, María title: Oral hygiene habits and possible transmission of COVID-19 among cohabitants date: 2020-10-19 journal: BMC Oral Health DOI: 10.1186/s12903-020-01274-5 sha: doc_id: 266293 cord_uid: lqag2p3u BACKGROUND: To find out whether misuse of dental hygiene, in terms of certain dental habits, may facilitate the spread of COVID-19 among cohabiting individuals.
    keywords: brush; contamination; covid-19; hygiene; toothbrush; use
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        item: #1415 of 7819
          id: cord-266303-6igk5jmn
      author: Yang, Xiaopeng
       title: Acute kidney injury and renal replacement therapy in COVID-19 patients: a systematic review and meta-analysis
        date: 2020-11-03
       words: 3334
      flesch: 42
     summary: key: cord-266303-6igk5jmn authors: Yang, Xiaopeng; Tian, Shasha; Guo, Hui title: Acute kidney injury and renal replacement therapy in COVID-19 patients: a systematic review and meta-analysis date: 2020-11-03 journal: Int Immunopharmacol DOI: 10.1016/j.intimp.2020.107159 sha: doc_id: 266303 cord_uid: 6igk5jmn Purpose Reported rates of acute kidney injury (AKI) have varied significantly among studies of coronavirus disease 2019 (COVID-19) published to date. The present meta-analysis was conducted to gain clarity regarding AKI incidence and renal replacement therapy (RRT) use in COVID-19 patients.
    keywords: acute; aki; coronavirus; covid-19; kidney; patients; studies; study
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        item: #1416 of 7819
          id: cord-266307-w56rii2p
      author: Acheampong, Desmond Omane
       title: Male Predisposition to Severe COVID-19: Review of Evidence and Potential Therapeutic Prospects
        date: 2020-09-09
       words: 8849
      flesch: 42
     summary: Cytokine storm is one of the pathophysiological features of severe COVID-19, and it occurs as a result of over-activation of immune cells leading to severe inflammation and tissue damage. Severe inflammation in males is reported to facilitate progression of mild to severe COVID-19.
    keywords: ace2; activity; androgen; angiotensin; cells; covid-19; estrogen; expression; females; immune; infection; levels; patients; sars; study; women
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        item: #1417 of 7819
          id: cord-266313-b518n9dx
      author: Cao, Yu-chen
       title: Remdesivir for severe acute respiratory syndrome coronavirus 2 causing COVID-19: An evaluation of the evidence
        date: 2020-04-02
       words: 5557
      flesch: 45
     summary: bioRxiv; 2020 Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile Pathological findings of COVID-19 associated with acute respiratory distress syndrome SARS-CoV-2 viral load in upper respiratory specimens of infected patients GS-5734) protects African green monkeys from Nipah virus challenge The antiviral compound remdesivir potently inhibits RNAdependent RNA polymerase from Middle East respiratory syndrome coronavirus Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection Nucleotide prodrug GS-5734 is a broad-spectrum filovirus inhibitor that provides complete therapeutic protection against the development of Ebola virus disease (EVD) in infected non-human primates Summaries of evidence from selected experimental therapeutics A randomized, controlled trial of Ebola virus disease therapeutics The pathogenesis of Ebola virus disease Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys Nucleosides for the treatment of respiratory RNA virus infections The first case of 2019 novel coronavirus pneumonia imported into Korea from Wuhan, China: implication for infection prevention and control measures COVID-19 control in China during mass population movements at New Year Remdesivir as a possible therapeutic option for the COVID-19 Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease Synthesis and antiviral activity of a series of 1'-substituted 4-aza-7,9-dideazaadenosine C-nucleosides Travel Medicine and Infectious Disease xxx The 53% fatality rate was not significantly different from the average 50% fatality rate of Ebola virus infection, and as a result, phase II clinical trials were stopped.
    keywords: coronavirus; cov-2; covid-19; drug; ebola; infection; patients; remdesivir; sars; treatment; trials; virus
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        item: #1418 of 7819
          id: cord-266324-uvsmbrbf
      author: Zhang, Hu
       title: Clinical characteristics of Coronavirus Disease (COVID-19) patients with gastrointestinal symptoms: A report of 164 cases
        date: 2020-05-08
       words: 2338
      flesch: 43
     summary: In Wuhan, the proportion of COVID-19 patients who experience gastrointestinal symptoms is relatively high. Therefore, we determined that a retrospective analysis of cases might be useful for clinicians to identify the clinical characteristics of COVID-19 patients with gastrointestinal symptoms.
    keywords: cov-2; covid-19; group; patients; sars; symptoms
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        item: #1419 of 7819
          id: cord-266377-3krv9ekb
      author: Nakayachi, Kazuya
       title: Why Do Japanese People Use Masks Against COVID-19, Even Though Masks Are Unlikely to Offer Protection From Infection?
        date: 2020-08-04
       words: 2525
      flesch: 43
     summary: Mask usage was regressed by the six psychological reasons to wear masks, removing the products above to avoid multicollinearity, and in order to compare the explanatory power of the psychological reasons. By contrast, frequency of mask usage depended much less on the participants' perceived severity of the disease and the efficacy of masks in reducing infection risk both for themselves and for others.
    keywords: covid-19; masks; pandemic; people; risk; wearing
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        item: #1420 of 7819
          id: cord-266382-co3n724s
      author: Cordeiro-Rodrigues, Luís
       title: Social Justice for Public Health: The COVID-19 Response in Portugal
        date: 2020-11-09
       words: 3442
      flesch: 38
     summary: In other words, the existing correlation between Portuguese social justice policies and positive outcomes for public health, which mitigated the spread of COVID-19, can be explained by the fact that those policies allowed and encouraged conditions for more social-distancing to take place, and thereby less infections of COVID-19 and other contagious diseases to occur; further, by providing incentives for the socio-economically vulnerable population to use the nation's health services, the policies expedited detection of infections, thereby reducing the probability of an infection spread. Secondly, while previous research hypothesized about social justice policies in the context of Africa and Australia, the present study focuses on Portugal.
    keywords: covid-19; government; health; measures; pandemic; policies; public; social
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        item: #1421 of 7819
          id: cord-266392-bayabroa
      author: Brenner, Erica J.
       title: BENIGN EVOLUTION OF SARS-CoV2 INFECTIONS IN CHILDREN WITH INFLAMMATORY BOWEL DISEASE: RESULTS FROM TWO INTERNATIONAL DATABASES
        date: 2020-10-12
       words: 1246
      flesch: 38
     summary: A recent analysis in IBD patients from the SECURE-IBD registry revealed older age, steroid medication and comorbidities as risk factors for severe evolution, while the same study showed that the 29 IBD patients less 20 years had only mild disease courses. Bowel Disease (SECURE-IBD) and the COVID-19 database of the Paediatric IBD Porto group of the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) were created in March 2020 with the aim to monitor outcomes of COVID-19 occurring in IBD patients.
    keywords: covid-19; ibd; patients
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        item: #1422 of 7819
          id: cord-266394-ehh61x5c
      author: Katsoulis, M.
       title: Obesity during the COVID-19 pandemic: cause of high risk or an effect of lockdown? A population-based electronic health record analysis in 1 958 184 individuals.
        date: 2020-06-23
       words: 3903
      flesch: 46
     summary: key: cord-266394-ehh61x5c authors: Katsoulis, M.; Pasea, L.; Lai, A.; Dobson, R. J.; Denaxas, S.; Hemingway, H.; Banerjee, A. title: Obesity during the COVID-19 pandemic: cause of high risk or an effect of lockdown? Due to BMI change during the lockdown, we estimated that 97 755 (5.4%: normal weight to overweight, 5.0%: overweight to obese and 1.3%: obese to severely obese) to 434 104 individuals (15%: normal weight to overweight, 15%: overweight to obese and 6%: obese to severely obese) individuals would be at higher risk for COVID-19 over one year.
    keywords: bmi; covid-19; individuals; license; medrxiv; obesity; preprint; risk
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        item: #1423 of 7819
          id: cord-266429-0xaz8kbs
      author: Bader, Feras
       title: Heart failure and COVID-19
        date: 2020-07-27
       words: 5007
      flesch: 30
     summary: Heart failure patients on advanced therapies including those with heart transplantation will particularly benefit from involving the advanced heart failure team members in the overall management if they contract the virus. Moreover, heart failure patients on advanced therapies may also be on medications that interact with suggested COVID-19 regimens.
    keywords: cardiac; clinical; coronavirus; covid-19; disease; failure; heart; infection; pandemic; patients; risk
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        item: #1424 of 7819
          id: cord-266440-69l9c3my
      author: Rochwerg, Bram
       title: Misinformation During the Coronavirus Disease 2019 Outbreak: How Knowledge Emerges From Noise
        date: 2020-04-29
       words: 3420
      flesch: 32
     summary: This classic research model does not fit well with pandemic research, where there is a need for rapid information to fill gaps and address public concern. Research funding bodies can help by prolonging funding periods, augmenting funding envelops to help overcome the barriers mentioned above, and considering funding pandemic research even outside pandemic times.
    keywords: covid-19; data; health; information; misinformation; pandemic; patients; public; research
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        item: #1425 of 7819
          id: cord-266456-10tjzqep
      author: Sadeghipour, Parham
       title: Management of ST‐segment‐elevation myocardial infarction during the coronavirus disease 2019 (COVID‐19) outbreak: Iranian“247” National Committee's position paper on primary percutaneous coronary intervention
        date: 2020-04-22
       words: 1438
      flesch: 38
     summary: The management of antiplatelet therapy in acute coronary syndrome patients with thrombocytopenia: a clinical conundrum Guideline on the management of bleeding in patients on antithrombotic agents Guideline for reversal of antithrombotics in intracranial hemorrhage: a statement for healthcare professionals from the Neurocritical Care Society and Society of Critical Care Medicine The Occupational Safety and Health Administration Getting to the heart of the matter: a review of drug interactions between HIV antiretrovirals and cardiology medications Resuscitation Council UK Statement on COVID-19 in relation to CPR and resuscitation in first aid and community settings Management of ST-segment-elevation myocardial infarction during the coronavirus disease 2019 (COVID-19) outbreak: Iranian247 National Committee's position paper on primary percutaneous coronary intervention The evolving pandemic of COVID-19 and interventional cardiology Catheterization laboratory considerations during the coronavirus (COVID-19) pandemic: from ACC's interventional council and SCAI Acute coronary syndromes in COVID-19: treatment considerations How to balance acute myocardial infarction and COVID-19: the protocols from Sichuan Provincial People's Hospital Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures Clinical features of patients infected with 2019 novel coronavirus in Wuhan Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients Primary versus tenecteplase-facilitated percutaneous coronary intervention in patients with ST-segment elevation acute myocardial infarction (ASSENT-4 PCI): randomised trial Long distance transport for primary angioplasty vs immediate thrombolysis in acute myocardial infarction.
    keywords: coronavirus; covid-19; infarction; management; patients; therapy
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        item: #1426 of 7819
          id: cord-266463-ci0g1dno
      author: Lopes, Renato D.
       title: Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: Impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
        date: 2020-05-13
       words: 5180
      flesch: 41
     summary: In a recent retrospective study of hospitalized COVID-19 patients, all-cause mortality was lower among patients on ACEI/ARB therapy when compared with those not using ACEI/ARBs. This is one of several questions facing physicians in the setting of COVID-19 and data are needed from randomized clinical trials like BRACE CORONA.
    keywords: acei; angiotensin; arb; clinical; covid-19; days; heart; patients; study; trial
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        item: #1427 of 7819
          id: cord-266466-5sgfx7oq
      author: Mansour, Amani
       title: First Case of an Infant with COVID-19 in the Middle East
        date: 2020-04-03
       words: 1508
      flesch: 51
     summary: Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding A familial cluster of infection associated with the 2019 novel coronavirus indicating potential person-to-person transmission during the incubation period SARS-CoV-2 infection in children Detection of covid-19 in children in early An epidemiological study on COVID-19: a rapidly spreading disease Coronavirus disease (COVID-19) and pediatric patients: a review of epidemiology, symptomatology, laboratory and imaging results to guide the development of a management algorithm A bibliometric analysis of COVID-19 research activity: a call for increased output A 55-day-old female infant infected with COVID 19: presenting with pneumonia, liver injury, and heart damage Novel coronavirus infection in hospitalized infants under 1 year of age in China A case series of children with 2019 novel coronavirus infection: clinical and epidemiological features Clinical and CT features in pediatric patients with COVID-19 infection: different points from adults Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study Health communication research in the Arab world: a bibliometric analysis COVID-19 related pediatric symptoms can exhibit an array of presentations, including diarrhea.
    keywords: children; covid-19; patient; symptoms
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        item: #1428 of 7819
          id: cord-266469-n484zqq1
      author: King, Michael J.
       title: Lung base CT findings in COVID-19 adult patients presenting with acute abdominal complaints: case series from a major New York City health system
        date: 2020-07-04
       words: 4135
      flesch: 39
     summary: key: cord-266469-n484zqq1 authors: King, Michael J.; Lewis, Sara; El Homsi, Maria; Hernandez Meza, Gabriela; Bernheim, Adam; Jacobi, Adam; Chung, Michael; Taouli, Bachir title: Lung base CT findings in COVID-19 adult patients presenting with acute abdominal complaints: case series from a major New York City health system date: 2020-07-04 journal: To describe demographic, clinical, and lung base CT findings in COVID-19 patients presenting with abdominal complaints.
    keywords: base; clinical; covid-19; findings; lung; patients; study; symptoms
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        item: #1429 of 7819
          id: cord-266478-642m488a
      author: Gino, Bruno
       title: Automated Inflating Resuscitator (AIR): Design and Development of a 3D-Printed Ventilator Prototype and Corresponding Simulation Scenario Based on the Management of a Critical COVID-19 Patient
        date: 2020-07-11
       words: 5442
      flesch: 46
     summary: Time is wasted adjusting AIR parameters after patient is connected. Referral hospitals are not receiving transfers due to the high influx of COVID-19 patients.
    keywords: air; bag; bvm; covid-19; oxygen; participants; patient; pressure; simulation; use; valve; ventilator
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        item: #1430 of 7819
          id: cord-266501-7jkzbmsf
      author: Ying, Wang
       title: Drugs supply and pharmaceutical care management practices at a designated hospital during the COVID-19 epidemic
        date: 2020-04-06
       words: 2595
      flesch: 38
     summary: According to COVID-19 prevention and control policy and requirements, combined with series of diagnosis and treatment plans, pharmacists in the first provincial-level COVID-19 diagnosis and treatment unit in Jilin Province in Northeast China have established the management practices of drug supply and pharmaceutical care from four aspects: personnel, drugs supply management, off-label drug use management and pharmaceutical care. List of THJU COVID-19 treatment drugs
    keywords: control; covid-19; drug; health; pharmaceutical; pharmacists; prevention; treatment
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        item: #1431 of 7819
          id: cord-266549-g8060w8v
      author: Gkentzi, Despoina
       title: Challenges for the Pediatricians During the Coronavirus Disease 2019 Pandemic Start From the Neonatal Period
        date: 2020-06-05
       words: 1418
      flesch: 42
     summary: COVID-19 infection does not seem more severe than other CoV or influenza infections in this population, possibly as all infect Angiotensin-Converting Enzyme 2 receptors in the upper airways. We fully agree with the suggested management and approach, although the latter still poses major further logistical issues such as the availability of negative pressure rooms for all inpatients with suspected COVID-19 infection pending virologic confirmation.
    keywords: bcg; covid-19; infants; infection
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        item: #1432 of 7819
          id: cord-266569-cf3mfp3e
      author: Senefeld, J.
       title: Therapeutic use of convalescent plasma in COVID-19 patients with immunodeficiency: A systematic review
        date: 2020-11-10
       words: 2307
      flesch: 37
     summary: Convalescent plasma was also found to be safe and efficacious in COVID-19 patients with common variable immunodeficiency, myasthenia gravis, and Sjögren's syndrome, in addition to COVID-19 patients with heart rhythm abnormalities and gravida. Thus, herein we summarize the literature detailing the clinical experiences of patients with primary and secondary immunosuppression who were transfused with COVID-19 convalescent plasma.
    keywords: convalescent; covid-19; immunodeficiency; patients; plasma; preprint
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        item: #1433 of 7819
          id: cord-266573-vfl08i2p
      author: Largent, Emily A
       title: Paying Participants in COVID-19 Trials
        date: 2020-05-29
       words: 3638
      flesch: 30
     summary: These difficult background circumstances do not make offers of payment to COVID-19 research participants impermissible. We argue that COVID-19 trial participants should usually be offered reimbursement for research-related expenses, and compensation for their time and effort, as for other types of research under usual circumstances.
    keywords: covid-19; incentives; participants; participation; research; trials
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        item: #1434 of 7819
          id: cord-266601-4ik5gu6b
      author: Peter, Strang
       title: Dying from Covid-19: Loneliness, end-of-life discussions and support for patients and their families in nursing homes and hospitals. A national register study
        date: 2020-07-25
       words: 3803
      flesch: 57
     summary: Nursing home patients were older (86.4 vs. 80.7 years, p<0.0001) and were more often female (56% vs. 37%, p<0.00001). In comparisons between nursing homes and hospital deaths, more patients dying in nursing homes were women (56% vs. 37%, p<0.0001) and significantly fewer had a retained ability to express their will during the last week of life (54% vs. 89%, p<0.0001).
    keywords: deaths; dying; homes; hospitals; nursing; patients
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        item: #1435 of 7819
          id: cord-266627-rkupc9w0
      author: Liu, Chengyin
       title: Clinical characteristics and antibiotics treatment in suspected bacterial infection patients with COVID-19
        date: 2020-11-03
       words: 2757
      flesch: 38
     summary: In conclusion, patients with suspected bacterial infection were more likely to have negative clinical outcomes than those without bacterial infection. For bacterial infection, the COVID-19 patients were grouped as suspected bacterial infection (SI) and no evidence of bacterial infection (NI).
    keywords: acute; antibiotics; covid-19; infection; injury; patients
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        item: #1436 of 7819
          id: cord-266643-53b0qdcl
      author: Ayyaz, Mahmood
       title: Combating COVID 19 in a public sector hospital in Pakistan
        date: 2020-10-22
       words: 1743
      flesch: 61
     summary: Operational Planning Guidelines and COVID-19 Partners Platform to support country preparedness and response Real-time RT-PCR in COVID-19 detection: issues affecting the results Management of critically ill patients with COVID-19 in ICU: statement from front-line intensive care experts in Wuhan, China. In collaboration of the department of medicine and infectious diseases it was decided that the health care professionals in areas of high COVID-19 risk would perform duty for a week and then isolate for the next two weeks.
    keywords: covid-19; disease; health; patients
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        item: #1437 of 7819
          id: cord-266648-962r0vm8
      author: Grossberg, Laurie B
       title: Review of Societal Recommendations Regarding Management of Patients With Inflammatory Bowel Disease During the SARS-CoV-2 Pandemic
        date: 2020-07-03
       words: 3618
      flesch: 42
     summary: Coronavirus (COVID-19): what IBD patients should know About Crohn's & colitis: COVID-19 and IBD. Coronavirus (COVID-19) response Management of inflammatory bowel disease patients in the COVID-19 pandemic era: a Brazilian tertiary referral center guidance Joint GI society message on COVID-19 Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1 Evidence for gastrointestinal infection of SARS-CoV-2 Prolonged presence of SARS-CoV-2 viral RNA in faecal samples Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding Detection of SARS-CoV-2 in different types of clinical specimens Virological assessment of hospitalized patients with COVID-2019 European Crohn's and Colitis Organisation.
    keywords: cov-2; covid-19; disease; ibd; pandemic; patients; risk; sars
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        item: #1438 of 7819
          id: cord-266650-2kkw9nwa
      author: Gupta, L.
       title: Management of rheumatic diseases in the times of COVID-19 pandemic- perspectives of rheumatology practitioners from India
        date: 2020-04-07
       words: 2584
      flesch: 46
     summary: key: cord-266650-2kkw9nwa authors: Gupta, L.; Misra, D.; Agarwal, V.; Balan, S. title: Management of rheumatic diseases in the times of COVID-19 pandemic- perspectives of rheumatology practitioners from India date: 2020-04-07 journal: nan DOI: 10.1101/2020.04.03.20048389 sha: doc_id: 266650 cord_uid: 2kkw9nwa Background. The Coronavirus disease 19 (COVID-19) pandemic has led to widespread concerns about the risk of infection in patients with rheumatic diseases (RD) receiving disease modifying ant-rheumatic drugs (DMARDs) and other immunosuppressants (IS).
    keywords: covid-19; license; medrxiv; pandemic; patients; preprint
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        item: #1439 of 7819
          id: cord-266672-t85wd0xq
      author: Bagnera, Silvia
       title: Performance of Radiologists in the Evaluation of the Chest Radiography with the Use of a “new software score” in Coronavirus Disease 2019 Pneumonia Suspected Patients
        date: 2020-07-20
       words: 3064
      flesch: 38
     summary: The average time for obtaining the result with the automatic software was between 7 s (e.g., zero COVID-19 score) and 21 s (e.g., with COVID-19 score from 6 to 12). In fact, the class with COVID-19 score from 0 to 4 correlates with negative imaging and pauci-symptomatic patient.
    keywords: chest; covid-19; cxr; patients; score
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        item: #1440 of 7819
          id: cord-266713-rghowch1
      author: Reyes-Bueno, JA
       title: Case fatality of COVID-19 in patients with neurodegenerative dementia
        date: 2020-10-07
       words: 2801
      flesch: 47
     summary: Our results suggest that case fatality of COVID-19 is significantly higher among patients with primary degenerative dementia than in other patients with similar mean ages and comorbidities. Our study suggests that the case fatality of COVID-19 is significantly higher in patients with primary degenerative dementia than among other patients with similar ages and comorbidities.
    keywords: case; covid-19; dementia; fatality; patients
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        item: #1441 of 7819
          id: cord-266744-31p212aq
      author: Dick, Lachlan
       title: Changes in Emergency General Surgery During Covid-19 in Scotland: A Prospective Cohort Study
        date: 2020-08-28
       words: 2254
      flesch: 44
     summary: Although not large in numbers, our experience of surgery in Covid-19 patients is comparable with the literature [7] . We demonstrate that the majority of emergency general surgical patients did not undergo Covid-19 testing; however, this may be due to initial limitations of testing.
    keywords: appendicitis; covid-19; emergency; patients; surgery
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        item: #1442 of 7819
          id: cord-266750-41gth6o0
      author: Puzzitiello, Richard N.
       title: Inflammatory and Coagulative Considerations for the Management of Orthopaedic Trauma Patients With COVID-19: A Review of the Current Evidence and Our Surgical Experience
        date: 2020-05-14
       words: 3746
      flesch: 34
     summary: The authors of this study also concluded that the characteristics and prognosis of COVID-19 patients with fractures tend to be more severe than those reported for COVID+ patients without fractures. The following precautions may be appropriate when dealing with unprecedented challenges associated with COVID-19 patients presenting with orthopaedic trauma injuries.
    keywords: covid-19; disease; fractures; hit; intramedullary; patients; response; trauma; treatment
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        item: #1443 of 7819
          id: cord-266755-y2lf7ssp
      author: Yehualashet, Awgichew Shewasinad
       title: ACEIs and ARBs and Their Correlation with COVID-19: A Review
        date: 2020-09-16
       words: 4176
      flesch: 37
     summary: As per Fang et al (2020), it was hypothesized that the use of ACE2 receptor increasing drugs is at higher risk for severe COVID-19 infection. ACEI initially inhibits ACE leading to decreased angiotensin I levels, causing a possible negative feedback loop that ultimately upregulates more ACE2 receptor to be able to interact with the decreased angiotensin I substrate available.
    keywords: ace2; aceis; angiotensin; arbs; coronavirus; cov-2; covid-19; infection; receptor; sars
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        item: #1444 of 7819
          id: cord-266791-ng1xlvkf
      author: Zhang, W.
       title: Leukopenia of Asymptomatic COVID-19 Infections under 18 Years Old in Recovery Stage
        date: 2020-05-26
       words: 3617
      flesch: 54
     summary: The literature has proved that in the routine blood test of COVID-19 patients, the occurrence of white blood cells or lymphocyte count decreased were common phenomenon 9, 18 , and the number of white blood cells in both mild and moderate types is mostly decreased. Additionally, in view of the small number of COVID-19 patients in Guizhou province, the sample size of patients under 18 years old with COVID-19 in this study was small, so our conclusion will be verified by more studies in the future.
    keywords: asymptomatic; covid-19; license; medrxiv; patients; preprint
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        item: #1445 of 7819
          id: cord-266799-t7lqlv41
      author: Rotejanaprasert, Chawarat
       title: Preliminary estimation of temporal and spatiotemporal dynamic measures of COVID-19 transmission in Thailand
        date: 2020-09-24
       words: 5039
      flesch: 40
     summary: To approximate the disease dynamics at this early phase we adopted statistical methods to estimate disease transmission measures under various assumptions. Introduction Two critical pieces of information when a new emerging infectious disease epidemic occurs are the mechanism of disease transmission and how infectious it is.
    keywords: cases; control; covid-19; data; disease; number; reproduction; thailand; time; transmission
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        item: #1446 of 7819
          id: cord-266808-wyuodzyt
      author: Nagler, Arielle R
       title: Early Results from SARS-CoV-2 PCR testing of Healthcare Workers at an Academic Medical Center in New York City
        date: 2020-06-28
       words: 1595
      flesch: 47
     summary: Employee testing is critical for workforce planning since COVID-19 positive employees require home-isolation for 10 days. [3] Although specifically designed for symptomatic testing, RT-PCR can be used to detect COVID-19 infection in both symptomatic and asymptomatic individuals.
    keywords: testing
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        item: #1447 of 7819
          id: cord-266813-5tttyl5o
      author: DeFilippis, Ersilia M.
       title: Cardiopulmonary Resuscitation During the COVID-19 Pandemic: A View From Trainees on the Front Line
        date: 2020-06-09
       words: 1175
      flesch: 40
     summary: Surviving sepsis campaign: guidelines on the management of critically ill adults with coronavirus disease 2019 (COVID-19) Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Hospitals consider universal do-not-resuscitate orders for coronavirus patients. At the time of hospital admission, all patients should have conversations with their clinicians about goals of care and preferences for resuscitation, regardless of their CO-VID-19 status; however, these conversations should be prioritized in older patients with multiple comorbidities who test positive.
    keywords: care; covid-19; cpr; patients
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        item: #1448 of 7819
          id: cord-266878-z7qn80tw
      author: Cho, Pauline
       title: COVID 19—An eye on the virus
        date: 2020-05-31
       words: 1443
      flesch: 49
     summary: However, it is well recognized that contact lens patients are frequently not compliant Regarding the use of contact lenses during this period of worldwide infection, mixed messages have emerged from various health sources, making it difficult for practitioners to provide absolute guidance to their patients.
    keywords: contact; lenses; patients
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        item: #1449 of 7819
          id: cord-266896-unb9yvjr
      author: Nihei, Yoshihito
       title: Continuous extracorporeal treatments in a dialysis patient with COVID-19
        date: 2020-10-04
       words: 2827
      flesch: 40
     summary: Extracorporeal treatment approaches have been used to remove inflammatory cytokines in patients with septic shock and ARDS, whereas several studies have reported the efficacy of PE, PMX-DHP and CHDF in patients with COVID-19 However, until today the efficacy of removing cytokines by extracorporeal treatments in patients with COVID-19 is unclear.
    keywords: covid-19; cytokine; day; patient; storm; treatment
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        item: #1450 of 7819
          id: cord-266916-flskltdf
      author: Malik, Jahanzeb
       title: Paying in Blood: A Case of Thrombocytopenia in Covid-19
        date: 2020-08-16
       words: 1044
      flesch: 50
     summary: There is only one case report published recently on idiopathic COVID-19 associated thrombocytopenia key: cord-266916-flskltdf authors: Malik, Jahanzeb; Javaid, Muhammad; Majedi, Omaid; Ishaq, Uzma; Zahid, Tayyaba title: Paying in Blood: A Case of Thrombocytopenia in Covid-19 date: 2020-08-16 journal: Cureus DOI: 10.7759/cureus.9791 sha: doc_id: 266916 cord_uid: flskltdf Novel coronavirus disease 2019 (COVID-19) primarily involves the respiratory system.
    keywords: case; covid-19; thrombocytopenia
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        item: #1451 of 7819
          id: cord-266932-567lbktm
      author: Escalard, Simon
       title: Early Brain Imaging Shows Increased Severity of Acute Ischemic Strokes With Large Vessel Occlusion in COVID-19 Patients
        date: 2020-08-19
       words: 1439
      flesch: 37
     summary: Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in ST-segment elevation in patients with covid-19 -a case series Identification of imaging selection patterns in acute ischemic stroke patients and the influence on treatment and clinical trial enrollment decision making Collateral effect of covid-19 on stroke evaluation in the United States Current concepts in imaging and endovascular treatment of acute ischemic stroke: implications for the clinician While a higher severity of these patients could be expected from the addition of both respiratory and neurological injury, COVID-19 patients with strokes can present with mild or none respiratory symptoms.
    keywords: covid-19; occlusion; patients; stroke
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        item: #1452 of 7819
          id: cord-266935-bkan3mwy
      author: Giannakoulis, Vassilis G.
       title: Effect of Cancer on Clinical Outcomes of Patients With COVID-19: A Meta-Analysis of Patient Data
        date: 2020-06-08
       words: 2883
      flesch: 47
     summary: An experience in Characteristics of Hospitalized Adults With COVID-19 in an Integrated Health Care System in California Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in Iran: A single center study Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City Covid-19 testing, hospital admission, and intensive care among 2,026,227 United States Veterans aged 54-75 years Characteristics and outcomes of a cohort of SARS-CoV-2 patients in the Province of Reggio Emilia Clinical characteristics of imported and second-generation COVID-19 cases outside Wuhan, China: A multicenter retrospective study Clinical features and treatment of COVID-19 patients in northeast Chongqing Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical features of 69 cases with coronavirus disease Clinical characteristics of coronavirus disease 2019 in Hainan Retrospective study of risk factors for severe SARS-Cov-2 infections in hospitalized adult patients Clinical features and outcomes of 221 patients with COVID-19 in Wuhan Risk factors for disease severity, unimprovement, and mortality in COVID-19 patients in Wuhan, China CT features of SARS-CoV-2 pneumonia according to clinical presentation: a retrospective analysis of 120 consecutive patients from Wuhan city Clinical characteristics and durations of hospitalized patients with COVID-19 in Beijing: A retrospective cohort study A multicentre study of 2019 novel coronavirus disease outcomes of cancer patients in Wuhan Clinical characteristics of COVID-19-infected cancer patients: A retrospective case study in three hospitals within Wuhan, China Clinical characteristics and prognosis in cancer patients with COVID-19: Patients with cancer were more likely to need ICU admission than patients without cancer (3,220 events; RR, 1.56; 95% CI, 1.31 to 1.87; P , .0001; Fig 3) .
    keywords: cancer; clinical; covid-19; mortality; patients; studies
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        item: #1453 of 7819
          id: cord-266948-n7sltd1b
      author: Ahamed, Jasimuddin
       title: Severe aortic stenosis patient risk during the COVID-19 pandemic
        date: 2020-09-14
       words: 1316
      flesch: 38
     summary: key: cord-266948-n7sltd1b authors: Ahamed, Jasimuddin title: Severe aortic stenosis patient risk during the COVID-19 pandemic date: 2020-09-14 journal: Open Heart DOI: 10.1136/openhrt-2020-001355 sha: doc_id: 266948 cord_uid: n7sltd1b nan SARS-CoV-2 infection can be an additional and very dangerous comorbidity. 5 AS patients therefore may have increased risk for developing thromboembolic complications during the valve replacement procedure or during subsequent hospitalisation and recovery if they are infected with SARS-CoV-2.
    keywords: covid-19; patients; risk; thrombosis
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        item: #1454 of 7819
          id: cord-266988-72uvawth
      author: Barth, Rolf F.
       title: The spectrum of pathological findings in coronavirus disease (COVID-19) and the pathogenesis of SARS-CoV-2
        date: 2020-07-14
       words: 2505
      flesch: 40
     summary: Consensus guidelines are now available for prevention, antithrombotic therapy, and follow-up for thrombotic and thromboembolic disease in COVID-19 patients [30] and the damping of the hyperimmune inflammatory response by the administration of Dexamethasone [31] . Hemophagocytic lymphohistiocytosis (HLH) has been postulated to have an important role in the progression of severe COVID-19 disease [28, 29] .
    keywords: covid-19; disease; infection; pathology; patients; sars
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        item: #1455 of 7819
          id: cord-266993-vt0aq7k6
      author: Casas Rojo, J. M.
       title: Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 Network.
        date: 2020-05-26
       words: 3721
      flesch: 49
     summary: https://doi.org/10.1101/2020.05.24.20111971 doi: medRxiv preprint Situación de COVID-19 en España Enfermedad por el coronavirus (COVID-19) Hospitalized Patients with 2019 Novel Coronavirus-Infected Pneumonia in Wuhan Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical Characteristics of Coronavirus Disease 2019 in China Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy JAMA NIH Interim Guidelines Coronavirus Disease COVID-19 Clinical characteristics and outcomes of hospitalised patients with COVID-19 treated in Hubei (epicenter) and outside Hubei (non-epicenter): A Nationwide Analysis of China Not discharged at end of follow-up (after re-admission) 37 (0.6%) In this study, we analyze a large series of hospitalized patients with COVID-19 in Spain who have been included in the ongoing SEMI-COVID Network.
    keywords: admission; clinical; covid-19; data; license; patients; preprint; study
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        item: #1456 of 7819
          id: cord-267030-khzivbzy
      author: Jia, Peng
       title: Understanding the Epidemic Course in Order to Improve Epidemic Forecasting
        date: 2020-10-01
       words: 1926
      flesch: 35
     summary: Spatial lifecourse epidemiology provides a new perspective to understand the course of epidemics, especially pandemics, and a new toolkit to predict the course of future epidemics on the basis of big data. The advanced spatial and digital technologies provide a new perspective to understand the transmission patterns of epidemics, especially pandemics, and a new toolkit to predict the progression of future epidemics on the basis of big data.
    keywords: course; covid-19; data; epidemic
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        item: #1457 of 7819
          id: cord-267034-s3hf4bo5
      author: Palladino, Raffaele
       title: Excess Deaths and Hospital Admissions for COVID-19 Due to a Late Implementation of the Lockdown in Italy
        date: 2020-08-05
       words: 2430
      flesch: 49
     summary: There was an exponential increase in the number of new COVID-19 cases until March 22nd, followed by a sharp reduction (Table 1; Figure 1 ). There was an exponential increase in the number of new COVID-19 cases until March 22nd, followed by a sharp reduction (Table 1; Figure 1 ).
    keywords: admissions; cases; covid-19; icu; lockdown
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        item: #1458 of 7819
          id: cord-267055-xscwk74r
      author: Chassagnon, Guillaume
       title: AI-Driven quantification, staging and outcome prediction of COVID-19 pneumonia
        date: 2020-10-15
       words: 5158
      flesch: 34
     summary: In conclusion, we show that the combination of chest CT and artificial intelligence can provide tools for fast, accurate and precise disease extent quantification as well as the identifica- Tensorflow: Large-scale machine learning on heterogeneous distributed systems Lung pattern classification for interstitial lung diseases using a deep convolutional neural network Semantic segmentation of pathological lung tissue with dilated fully convolutional networks Segnet: A deep convolutional encoder-decoder architecture for image segmentation Classification of interstitial lung abnormality patterns with an ensemble of deep convolutional neural networks Performance of a new quantitative computed tomography index for interstitial lung disease assessment in systemic sclerosis Quantification of tomographic patterns associated with covid-19 from chest ct Deep learning: definition and perspectives for thoracic imaging Computer-aided diagnosis of pulmonary fibrosis using deep learning and ct images Interstitial lung disease associated with systemic sclerosis (ssc-ild) Automated classification of usual interstitial pneumonia using regional volumetric texture analysis in high-resolution ct Deformable registration through learning of context-specific metric aggregation A texton-based approach for the classification of lung parenchyma in ct images Holistic classification of ct attenuation patterns for interstitial lung diseases via deep convolutional neural networks Diabetes is a risk factor for the progression and prognosis of covid-19 Synergistic learning of lung lobe segmentation and hierarchical multi-instance classification for automated severity assessment of covid-19 in ct images Serial quantitative chest ct assessment of covid-19: Deep-learning approach. The paper is organized as follows: we first review related work mainly focusing on interstitial lung diseases (ILDs) diseases, which is followed by a description of all the components and implementation details of our method.
    keywords: covid-19; disease; et al; imaging; learning; lung; patients; quantification; staging; term
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        item: #1459 of 7819
          id: cord-267075-0wtgycv5
      author: Mouawad, Nicolas J.
       title: The Vascular Surgery Covid-19 Collaborative (VASCC)
        date: 2020-04-22
       words: 369
      flesch: 48
     summary: Furthermore, in an effort to preserve the very scarce assets of personal protective 9 equipment as well as Intensive Care Unit resources, such as ventilators, medications, and trained 10 personnel, elective vascular surgical cases have decreased significantly. Given these discussions, most vascular surgeons have reduced their 16 practice patterns to emergency vascular surgery and/or very urgent cases.
    keywords: covid-19
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        item: #1460 of 7819
          id: cord-267076-a4ulg4ck
      author: Mechili, Enkeleint A.
       title: Is the mental health of young students and their family members affected during the quarantine period? Evidence from the COVID‐19 pandemic in Albania.
        date: 2020-07-13
       words: 4027
      flesch: 55
     summary: In comparison to other studies in student populations which used the PHQ-9 questionnaire, our study reported much higher depression levels (Kim et. al., 2019; Du et. al., 2017; Karekla et. Higher scores indicated higher depression levels (0-4 indicates minimal depression levels, 5-9 mild depression levels, 10-14 moderate depression levels, 15-19 moderate-severe depression levels and 20-27 severe depression levels).
    keywords: depression; family; health; students; study
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        item: #1461 of 7819
          id: cord-267117-e53jvt92
      author: Fahd Al‐Muhanna, Afnan
       title: COVID‐19: Impact and challenges at breast imaging unit
        date: 2020-05-25
       words: 560
      flesch: 57
     summary: All breast imaging studied should be delayed for known or suspected COVID-19 patients as per our hospital infection control policy. Breast J DOI: 10.1111/tbj.13891 sha: doc_id: 267117 cord_uid: e53jvt92 nan A Series of pneumonia cases of unknown cause were reported in Wuhan, China in December 2019, later found to be related to the novel coronavirus (2019-nCoV).
    keywords: coronavirus; covid-19
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        item: #1462 of 7819
          id: cord-267124-8efdzlc0
      author: Wichmann, Dominic
       title: Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: A Prospective Cohort Study
        date: 2020-05-06
       words: 4071
      flesch: 45
     summary: retrospective study Multiple roles of the coagulation protease cascade during virus infection Diagnosis, prevention, and treatment of thromboembolic complications in COVID-19: report of the National Institute for Public Health of the Netherlands Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past SARS-CoV-2 and viral sepsis: observations and hypotheses German recommendations for critically ill patients with COVID-19 The stimulation of thrombosis by hypoxia Histopathologic changes and SARS-CoV-2 immunostaining in the lung of a patient with COVID-19 Pulmonary pathology of early-phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer Effectiveness of convalescent plasma therapy in severe COVID-19 patients The characteristics of 50 hospitalized COVID-19 patients with and without ARDS Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up Current Author Addresses Dr. Becker: Department of Pulmonology and Internal Intensive Care, Asklepios Hospital Barmbek Dr. de Weerth: Department of Internal Medicine, Agaplesion Diakonie Hospital Author Contributions: Conception and design: D Provision of study materials or patients Standard weights for men and women (adopted from Molina and DiMaio [13, 14]), respectively, are as follows (the dependence of standard organ weights on body weight was not considered here): brain, 1401 g and 1233 g; heart, 331 g and 245 g; lung (right), 445 g and 340 g; lung (left), 395 g and 299 g; liver, 1561 g and 1288 g; kidney (right), 129 g and 108 g Figure 1 . To our knowledge, only 3 case reports have been published about COVID-19 patients who have undergone complete autopsy (7, 8) .
    keywords: autopsy; cases; cov-2; covid-19; death; findings; lung; patients; sars
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        item: #1463 of 7819
          id: cord-267142-ys7z7j8j
      author: Cheema, Marvi
       title: Keratoconjunctivitis as the initial medical presentation of the novel coronavirus disease 2019 (COVID-19)
        date: 2020-04-02
       words: 2468
      flesch: 41
     summary: Given this, eye care professionals, most notably ophthalmologists, may be the first point of contact in the health care field for patients with possible COVID-19, before the onset of characteristic respiratory symptoms. The case emphasizes the importance for eye care professionals to remain vigilant and consider SARS-CoV-2 as the causative agent in patients presenting with viral conjunctivitis, particularly in high-risk patients with travel to areas of active transmission of the virus.
    keywords: care; case; coronavirus; covid-19; eye; health; patient
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        item: #1464 of 7819
          id: cord-267152-m9m0aunk
      author: Yang, Philip
       title: Investigating the sex differences in COVID-19: Another step forward, but many unanswered questions
        date: 2020-06-28
       words: 1413
      flesch: 48
     summary: It is too early to determine whether sex differences identified in this study would have practical implications for management, especially because the numerous potential reasons for such differences still need to be further elucidated. These findings may be one of the potential reasons for the predominance of male patients (82%) in the Italian cohort of COVID-19 patients admitted to A
    keywords: covid-19; differences; patients
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        item: #1465 of 7819
          id: cord-267209-m0fvv1t7
      author: Sawyer, Michala R.
       title: Establishing Better Evidence on Remote Monitoring for Postpartum Hypertension: A Silver Lining of the Coronavirus Pandemic
        date: 2020-09-23
       words: 1847
      flesch: 32
     summary: As a consequence of the pandemic, we now have an opportunity to research the impact of postpartum remote blood pressure monitoring on maternal outcome and disparities within these outcomes. 8-10 One study found remote postpartum blood pressure monitoring increased in-person care engagement, with 88% of women who used remote monitoring attending their in-person 6-week postpartum visit, compared with a baseline attendance rate of 66%.
    keywords: blood; monitoring; postpartum; pressure; remote
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        item: #1466 of 7819
          id: cord-267243-ewivbfib
      author: Rodrigues, J.C.L.
       title: An update on COVID-19 for the radiologist - A British society of Thoracic Imaging statement
        date: 2020-05-31
       words: 1854
      flesch: 45
     summary: Where more than one scanner is available, dedicated use of only one scanner for COVID-19 patients may be ideal, depending on departmental and hospital geography. The British Society of Thoracic Imaging (BSTI) additionally aim to establish a database, allowing the imaging of COVID-19 patients to be uploaded anonymously.
    keywords: coronavirus; covid-19; disease; imaging; patients
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        item: #1467 of 7819
          id: cord-267257-kwy9puxo
      author: Greenhalgh, Sue
       title: Safety netting; best practice in the face of uncertainty
        date: 2020-05-12
       words: 2289
      flesch: 48
     summary: Safety netting is an already well-established General Practitioner (GP) diagnostic strategy which ensures that patients can be monitored over time until their symptoms resolve or become more florid (Evans et al, 2018) . As a consequence, CES credit cards were developed for patients at risk of CES, by CES sufferers and are a good example of safety netting advice (Greenhalgh et al, 2016) .
    keywords: covid-19; netting; patient; safety; symptoms
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        item: #1468 of 7819
          id: cord-267260-8l831mre
      author: Brenner, Erica J.
       title: Corticosteroids, but not TNF Antagonists, are Associated with Adverse COVID-19 Outcomes in Patients With Inflammatory Bowel Diseases: Results from an International Registry
        date: 2020-05-18
       words: 3149
      flesch: 38
     summary: We sought to characterize the clinical course of COVID-19 among IBD patients and evaluate the association between demographics, clinical characteristics, and immunosuppressant treatments on COVID-19 outcomes. Methods Surveillance Epidemiology of Coronavirus Under Research Exclusion for Inflammatory Bowel Disease (SECURE-IBD) is a large, international registry created to monitor outcomes of IBD patients with confirmed COVID-19.
    keywords: age; covid-19; disease; ibd; patients; tnf
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        item: #1469 of 7819
          id: cord-267268-50h13gso
      author: Spagnolo, Paolo
       title: Pulmonary fibrosis secondary to COVID-19: a call to arms?
        date: 2020-05-15
       words: 987
      flesch: 41
     summary: In a study of 36 patients who had recovered from MERS, chest x-rays taken a median of 43 (range 32-320) days after hospital discharge showed abnormalities described as lung fibrosis in about a third of the patients. In the first large series of hospitalised patients (n=138) with COVID-19 in Wuhan, China, chest CT showed bilateral ground glass opacities with or without consolidation and with lower lobe predilection in all patients.
    keywords: covid-19; lung; patients
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        item: #1470 of 7819
          id: cord-267271-cdeecuf0
      author: Liu, Nian
       title: Dynamic changes of Chest CT follow-up in Coronavirus Disease-19 (COVID-19) pneumonia: relationship to clinical typing
        date: 2020-08-05
       words: 3653
      flesch: 52
     summary: Therefore, the dynamic changes of different clinical types can be demonstrated by CT characteristics, but it is still difficult to distinguish the clinical types by initial CT characteristics. The interval time between initial CT and the first follow-up CT scan was defined as Interval-1, and the interval between initial CT and the second follow-up CT was defined as Interval-2, and so on.
    keywords: covid-19; follow; group; pneumonia; severity
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        item: #1471 of 7819
          id: cord-267287-qodj254z
      author: Pintado, Juan F.
       title: How COVID-19 has affected Emergent Visits to a Latin-American Trauma Department: Experience at a Peruvian National Trauma Referral Center
        date: 2020-11-03
       words: 3665
      flesch: 40
     summary: The protocol for COVID-19 positive patients with indication for an orthopedic procedure has been resume in Table 1 . Protocol for COVID-19 positive patients with indication for an orthopedic procedure during the government-mandated nationwide lockdown for COVID-19 in Peru.
    keywords: covid-19; emergency; fractures; hospital; number; pandemic; patients; trauma
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        item: #1472 of 7819
          id: cord-267296-u4svwcpt
      author: Rauch, Antoine
       title: Endotheliopathy Is Induced by Plasma From Critically Ill Patients and Associated With Organ Failure in Severe COVID-19
        date: 2020-11-10
       words: 1326
      flesch: 24
     summary: As a positive control for endothelial cell injury, Shigatoxin 145 (Sigma-Aldrich, Saint Quentin Fallavier, France) was spiked in plasma from healthy adults (10 µg/mL final concentration) and incubated at 37°C for 15 minutes,before addition to HPMVECs. Different pathways could be involved in endothelial cell injury during the course of COVID-19, ie, complement activation, cellular hypoxia, platelets, and direct cytotoxicity of cytokines such as IL-6, IL-1β, and tumor necrosis factor-α.
    keywords: covid-19; endothelial; icu; patients; plasma
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        item: #1473 of 7819
          id: cord-267300-zbipv9er
      author: Alalwan, Adel A
       title: A Hemodialysis Patient with Severe COVID-19 Pneumonia
        date: 2020-05-06
       words: 2355
      flesch: 45
     summary: Although the majority of COVID-19 pneumonia patients have normal serum procalcitonin (PCT), the patient had slightly elevated PCT on admission. Common abnormal radiographic findings in the chest x-rays of COVID-19 pneumonia patients were consolidation and ground-glass opacities, with bilateral, peripheral, and lower lung zone distributions.
    keywords: covid-19; disease; esrd; hemodialysis; patient; pneumonia; treatment
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        item: #1474 of 7819
          id: cord-267307-kyh0xsrp
      author: Kasting, Monica L.
       title: Public perceptions of the effectiveness of recommended non-pharmaceutical intervention behaviors to mitigate the spread of SARS-CoV-2
        date: 2020-11-04
       words: 4354
      flesch: 48
     summary: For purposes of analyses, we divided the sample using a median split, creating two groups: those who had lower perceived effectiveness of the NPI measures (score range: 1-3.99; 47.3% of the sample) and those who had higher perceived effectiveness (score range: 4.00-5.00; 52.7% of the sample). However, little is known about public perceptions of the effectiveness of these measures, and high perceived effectiveness is likely to be critical in order to achieve widespread adoption of NPI. METHODS:
    keywords: cov-2; covid-19; effectiveness; health; participants; public; sars
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        item: #1475 of 7819
          id: cord-267332-xc6dcb93
      author: Soltani, Marwa
       title: Biventricular thrombi associated with myocardial infarction in a patient with COVID-19: a case report
        date: 2020-06-26
       words: 948
      flesch: 34
     summary: It mostly occurs with anterior myocardial infarction when there is an aneurysm or apical akinesis 2 . Cardiovascular manifestations and treatment considerations in covid-19 Incidence, diagnostic methods, and evolution of left ventricular thrombus in patients with anterior myocardial infarction and low left ventricular ejection fraction: a prospective multicenter study Challenges in management of left ventricular thrombus Left Ventricular Thrombus in Patients With Acute Anterior Wall Myocardial Infarction
    keywords: covid-19; infarction; thrombi
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        item: #1476 of 7819
          id: cord-267343-a6fplmfj
      author: Brakman, Steven
       title: The turn from just-in-time to just-in-case globalization in and after times of COVID-19 An essay on the risk re-appraisal of borders and buffers
        date: 2020-06-02
       words: 5507
      flesch: 47
     summary: In addition, and irrespective of the precise configuration of a trade network for a particular sector, the increased uncertainty associated with international trade following (the perception of) an increased likelihood of global shocks like COVID-19 will stimulate all firms to be less reliant on global production chains and intermediate deliveries by keeping larger stocks or buffers themselves, on or nearby their production location. Becoming too dependent on global supply chains might lead to a re-evaluation of global trade and risk assessments.
    keywords: covid-19; economic; economy; globalization; international; production; risk; trade; world
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        item: #1477 of 7819
          id: cord-267389-v2ihhtl0
      author: Canevelli, Marco
       title: The Pipeline of Therapeutics Testing During the Emergency Phase of the COVID-19 Outbreak
        date: 2020-09-24
       words: 3094
      flesch: 34
     summary: However, it also represents a repository for the vast majority of clinical trial protocols conducted worldwide. The following data were abstracted by three authors (F.T., Ga.R., and Gi.R.) from the selected protocols: NCT (the unique identification code assigned by clinicaltrials.gov) and/or EudraCT codes; study phase; allocation and masking procedures; tested compound(s); way of administration; mechanism of action; primary outcome measure(s); expected primary completion date; expected number of participants; age range of participants; targeted COVID-19 related condition; sponsor; and location.
    keywords: covid-19; phase; protocols; studies; trials
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        item: #1478 of 7819
          id: cord-267397-b7ogeokm
      author: Smith, E. R.
       title: Protocol for a Sequential, Prospective Meta-Analysis to Describe COVID-19 in Pregnancy and Newborn Periods
        date: 2020-11-12
       words: 5616
      flesch: 45
     summary: Where appropriate and as sample size allows, we will consider meta-regression or subgroup analyses by the following study level characteristics: study design and sampling strategy, proportion of confirmed COVID-19 cases (out of suspected and confirmed cases), national maternal mortality ratio, national neonatal mortality rate. Among the 19 included studies, ten are COVID-19 registry studies, seven are cohort or surveillance studies, and two are case-control studies.
    keywords: case; covid-19; data; license; medrxiv; pregnancy; preprint; studies; study; women
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        item: #1479 of 7819
          id: cord-267402-kca05rvz
      author: South, Kieron
       title: Preceding infection and risk of stroke: An old concept revived by the COVID-19 pandemic
        date: 2020-07-24
       words: 6252
      flesch: 31
     summary: medRxiv, Epub ahead of print 2020 Dysregulation of Immune Response in Patients With Coronavirus Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome Clinical progression and cytokine profiles of middle east respiratory syndrome coronavirus infection Inflammatory cytokines and ischemic stroke risk: the REGARDS cohort Systemic infections cause exaggerated local inflammation in atherosclerotic coronary arteries: clues to the triggering effect of acute infections on acute coronary syndromes Inflammation and plaque vulnerability Infection and atherosclerosis development The role of immune cells in atrial fibrillation The role of infection in the development of non-valvular atrial fibrillation: up-regulation of Toll-like receptor 2 expression levels on monocytes Pandemic H1N1 influenza infection and vascular thrombosis Pulmonary artery thrombosis in a patient with severe acute respiratory syndrome Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Hypercoagulability of COVID-19 patients in intensive care unit: A report of thromboelastography findings and other parameters of hemostasis Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in C-reactive protein levels in the early stage of COVID-19 Procoagulant soluble tissue factor is released from endothelial cells in response to inflammatory cytokines The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome Mechanisms of Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury Thrombinactivatable fibrinolysis inhibitor and protein C inhibitor in interstitial lung disease Effects of inflammatory cytokines on the release and cleavage of the endothelial cell-derived ultralarge von Willebrand factor multimers under flow Inflammatory cytokines inhibit ADAMTS13 synthesis in hepatic stellate cells and endothelial cells Inflammationassociated ADAMTS13 deficiency promotes formation of ultra-large von Willebrand factor Acute respiratory tract infection leads to procoagulant changes in human subjects Analysis of thrombotic factors in severe acute respiratory syndrome (SARS) patients Involvement of ADAMTS13 and von Willebrand factor in thromboembolic events in patients infected with SARS-CoV-2 Epub ahead of print 23 ADAMTS13 activity, von Willebrand factor, factor VIII and D-dimers in COVID-19 inpatients High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women High levels of von Willebrand factor and low levels of its cleaving protease, ADAMTS13, are associated with stroke in young HIVinfected patients Thrombocytopenia and its association with mortality in patients with COVID-19 Antiplatelet Therapy After Percutaneous Coronary Intervention in Patients With COVID-19 Platelets and infection -an emerging role of platelets in viral infection Neutrophil extracellular traps in COVID-19 ADAMTS13-mediated thrombolysis of t-PA-resistant occlusions in ischemic stroke in mice Hypercoagulability is a stronger risk factor for ischaemic stroke than for myocardial infarction: a systematic review Severe COVID-19 infection associated with endothelial activation Electron microscopy of SARS-CoV-2: a challenging task -authors' reply Aberrant coagulation causes a hyper-inflammatory response in severe influenza pneumonia Immunopathogenesis of coronavirus infections: implications for SARS Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease Central nervous system manifestations of COVID-19: a systematic review Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 Central nervous system infections and stroke -a population-based analysis The neutrophil in vascular inflammation COVID-19 and cardiovascular disease Defining causality in COVID-19 and neurological disorders Thromboprophylaxis in intensive care unit patients: a literature review Risk of Ischemic Stroke in Patients with Covid-19 versus Patients with Influenza Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis Coronavirus Infections and Type 2 Diabetes-Shared Pathways with Therapeutic Implications Obesity and impaired metabolic health in patients with COVID-19 Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California Increased risk of influenza among vaccinated adults who are obese Obesity, inflammation, and insulin resistance -a mini-review Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation Chest CT findings in cases from the cruise ship 'Diamond Princess' with coronavirus disease 2019 (COVID-19) Association between influenza vaccination and reduced risk of brain infarction Management of acute ischemic stroke in patients with COVID-19 infection: report of an international panel There is clear evidence, from post-mortem lung pathology, of extensive thrombosis in the alveolar capillaries and small vessels in response to COVID-19 infection.
    keywords: acute; cells; coronavirus; cov-2; covid-19; disease; factor; incidence; infection; patients; risk; sars; stroke
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        item: #1480 of 7819
          id: cord-267438-8e7wxzel
      author: Wu, Vincent
       title: Considerations for head and neck oncology practices during the coronavirus disease 2019 (COVID‐19) pandemic: Wuhan and Toronto experience
        date: 2020-04-27
       words: 3476
      flesch: 40
     summary: Most head and neck cancer care remains at the highest level of priority, and the need to provide ongoing head and neck oncology care remains clear. In 2003, SARS was immediately devastating to cancer care in both Canada and China.
    keywords: cancer; care; covid-19; head; health; neck; pandemic; patients; surgery; toronto
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        item: #1481 of 7819
          id: cord-267465-7rrveyrh
      author: Jiménez-Ruiz, Carlos A.
       title: COVID-19 Y TABAQUISMO: REVISIÓN SISTEMÁTICA Y METAANÁLISIS DE LA EVIDENCIA
        date: 2020-07-25
       words: 3928
      flesch: 38
     summary: Las principales fortalezas de este estudio son varias: a) la RS y MA que se han realizado han incluido una búsqueda de la literatura que ha consignado, al menos, 19 denominaciones del virus y de la enfermedad, incluyendo la denominación oficial de la Organización Mundial de la Salud del 11 de febrero de 2020 47 , b) hasta donde nosotros conocemos el estudio comprende la RS y el MA más amplios que se han realizado hasta el momento habiéndose incluido el mayor número de estudios y haber sido más estrictos al no haberse tomado en cuenta series de casos y haberse utilizado los datos crudos de los estudios, en cuyo caso la magnitud del efecto del tabaco hubiera sido menor, y c) las cifras de sensibilidad y heterogeneidad son asumibles y muestran que, aún retirando los artículos más discrepantes, el consumo de tabaco sigue siendo un factor de riesgo importante (0R: 1,59 IC 95%; 1,32-1,92. La adecuación de los artículos seleccionados al objeto del estudio y a los criterios de inclusión y con el fin de aumentar la fiabilidad y la seguridad del proceso fue realizada por dos autores del trabajo de forma independiente.
    keywords: 2019; artículos; como; con; covid-19; del; enfermedad; estudios; factor; infección; las; los; mayor; más; para; patients; por; que; riesgo; tabaco; una; wuhan
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        item: #1482 of 7819
          id: cord-267476-j59tm40d
      author: Yong, Sarah Ee Fang
       title: Connecting clusters of COVID-19: an epidemiological and serological investigation
        date: 2020-04-21
       words: 3569
      flesch: 44
     summary: We have highlighted the importance of serological testing for epidemiological investigation of COVID-19 cases, and we urge further development of serological testing capabilities. We present findings of investigations from Jan 29 to Feb 24, 2020, that linked two people with COVID-19 from Wuhan, China, to three clusters of COVID-19 cases in Singapore.
    keywords: cases; church; clusters; cov-2; covid-19; sars; singapore; testing
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        item: #1483 of 7819
          id: cord-267482-afqfymbq
      author: Ryu, Seungjin
       title: Ketogenesis restrains aging-induced exacerbation of COVID in a mouse model
        date: 2020-09-12
       words: 8214
      flesch: 40
     summary: For example, epithelial cell specific induction of hACE2 (K18-hACE2) as a model of SARS-CoV-2 infection demonstrated that post intranasal inoculation, animals develop lung inflammation and pneumonia driven by infiltration of monocytes, neutrophils and T cells . Interestingly, some of the most striking changes occurred in T cells, where ketogenesis led to a substantial increase in ϒδ but not αβ T cells ( Figure 6C and Figure S6B ).
    keywords: a59; aging; cells; cov-2; covid-19; et al; expression; figure; infection; inflammasome; inflammation; mcov; mice; model; mouse; nlrp3; sars; ϒδ t
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        item: #1484 of 7819
          id: cord-267486-ipcvepia
      author: van den Heuvel, F. M. A.
       title: Cardiac function in relation to myocardial injury in hospitalised patients with COVID-19
        date: 2020-07-08
       words: 3794
      flesch: 45
     summary: To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) Cardiovascular disease, drug therapy, and mortality in Covid-19 Elevated troponin in patients with coronavirus disease 2019: possible mechanisms Coronaviruses and the cardiovascular system: acute and longterm implications CO-RADS-a categorical CT assessment scheme for patients with suspected COVID-19: definition and evaluation Chest CT findings of COVID-19 pneumonia by duration of symptoms Fourth universal definition of myocardial infarction Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging Cardiac function in relation to myocardial injury in hospitalised patients with COVID-19 Research to practice: assessment of left ventricular global longitudinal strain for surveillance of cancer chemotherapeutic-related cardiac dysfunction Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019 Pathological findings of COVID-19 associated with acute respiratory distress syndrome COVID-19 pandemic and cardiac imaging: Patients hospitalised at the ICU had a higher prevalence of elevated Troponin T and a lower prevalence of elevated NT-proBNP compared with patients who had only been hospitalised at the COVID-19 ward.
    keywords: cardiac; covid-19; dysfunction; embolism; injury; patients; probnp; troponin
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        item: #1485 of 7819
          id: cord-267494-186aztc3
      author: Wilder-Smith, Annelies
       title: Lockdown to contain COVID-19 is a window of opportunity to prevent the second wave
        date: 2020-05-30
       words: 1028
      flesch: 45
     summary: New cases continued to increase exponentially before peaking on 12 Policy-makers are debating two strategies to reduce deaths and the demand on health care utilization 6 , in addition to considering major collateral damage to economic, society, mental health and other outcomes: (a) containment or suppression of COVID-19, which aims to reverse the rate of epidemic growth, thereby reducing new case numbers to low levels, and (b) mitigation, which focuses on slowing but not necessarily stopping epidemic spread -to reduce peak healthcare demand while protecting those most at risk of severe disease from infection. Wuhan, central China, the unsuspecting ground zero of the COVID-19 outbreak, saw a tsunami of tens of thousands of COVID-19 cases quickly overwhelm their health care system within a matter of weeks.
    keywords: cases; covid-19; isolation
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        item: #1486 of 7819
          id: cord-267511-tb69dwg8
      author: Talebian, Sepehr
       title: Why Go NANO on COVID-19 Pandemic?
        date: 2020-09-02
       words: 1968
      flesch: 38
     summary: These NANOvaccines are examples as to how NANOtechnology can further enhance the therapeutic effect of COVID-19 vaccines. Currently, there are no specific vaccine or anti-viral treatments available for COVID-19, but a wide range of fields of science and technology, such as NANOtechnology, has great potential to help in the prevention, diagnosis, and treatment of COVID-19.
    keywords: coronavirus; covid-19; nanotechnology; vaccine; virus
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        item: #1487 of 7819
          id: cord-267519-a0bcmjkn
      author: Bravi, Francesca
       title: Predictors of severe or lethal COVID-19, including Angiotensin Converting Enzyme inhibitors and Angiotensin II Receptor Blockers, in a sample of infected Italian citizens
        date: 2020-06-24
       words: 3307
      flesch: 34
     summary: In conclusions, the present study did not find any association between COVID-19 severity and treatment with ARBs, ACE inhibitors, or both, and confirms previous findings in supporting the recommendation of several scientific societies to continue ARBs or ACE inhibitors medication for all patients, unless otherwise advised by their physicians, who should thus be reassured. Significant predictors of severe disease were older age (with AORs largely increasing after 70 years of age), male gender (AOR: 1.76; 1.40–2.23), diabetes (AOR: 1.52; 1.05–2.18), CVD (AOR: 1.88; 1.32–2.70) and COPD (AOR: 1.88; 1.11–3.20).
    keywords: ace; angiotensin; arbs; covid-19; disease; inhibitors; subjects
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        item: #1488 of 7819
          id: cord-267533-nmgtan4e
      author: Hu, Zhigang
       title: Delayed hospital admission and high-dose corticosteroids potentially prolong SARS-CoV-2 RNA detection duration of patients with COVID-19
        date: 2020-10-29
       words: 3608
      flesch: 39
     summary: By shrinking down to zero coefficient weights, LASSO regression analysis has the ability to eliminate exposures that are non-related to the outcome [9, 11] . In the first step of our study, we identified the independent risk factors of long-term positive SARS-CoV-2 RNA detection by using LASSO logistic regression analysis and SARS-CoV-2 RNA detection duration by using LASSO Cox regression analysis.
    keywords: covid-19; detection; duration; patients; rna; rna detection; sars
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        item: #1489 of 7819
          id: cord-267538-6u3mwzc9
      author: Mitra, Raman L.
       title: An algorithm for managing QT prolongation in coronavirus disease 2019 (COVID-19) patients treated with either chloroquine or hydroxychloroquine in conjunction with azithromycin: Possible benefits of intravenous lidocaine
        date: 2020-04-01
       words: 1978
      flesch: 36
     summary: U.S. Food and Drug Administration Cardiovascular risks with azithromycin and other antibacterial drugs Lack of association between azithromycin and death from cardiovascular cause Cardiovascular events and safety outcomes associated with azithromycin therapy: a meta-analysis of randomized controlled trials Azithromycin, cardiovascular risks, QTc interval prolongation, torsade de pointes, and regulatory issues: a narrative review based on the study of case reports HERG, a human inward rectifier in the voltage-gated potassium channel family Late sodium current block for drug-induced long QT syndrome: results from a prospective clinical trial Mexiletine prevents recurrent torsades de pointes in acquired long QT syndrome refractory to conventional measures Coronavirus fulminant myocarditis saved with glucocorticoid and human immunoglobulin First case of COVID-19 infection with fulminant myocarditis complication: case report and insights Coronavirus Disease 2019 (COVID-19) and cardiovascular disease This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. 4, 5 Nonetheless, these risks may be higher in critically ill, hospitalized COVID-19 patients with metabolic derangements, with organ failure, and on other medications, increasing the risk of drug-drug interactions.
    keywords: azithromycin; covid-19; hydroxychloroquine; patients
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        item: #1490 of 7819
          id: cord-267566-gdjl0qmu
      author: Kweon, Oh Joo
       title: Antibody kinetics and serologic profiles of SARS-CoV-2 infection using two serologic assays
        date: 2020-10-22
       words: 3604
      flesch: 46
     summary: Rigorous verification study with serially collected serum from COVID-19 patients is required to ensure analytic performance and clinical accuracy. In addition, both assays showed 94.2~96.4% of IgG specificities and increased IgG titers in COVID-19 patients were maintained.
    keywords: assays; cov-2; covid-19; igg; igm; patients; pso; sars
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        item: #1491 of 7819
          id: cord-267610-bzbr9ios
      author: Anastassopoulou, Cleo
       title: SARS-CoV-2 transmission, the ambiguous role of children and considerations for the reopening of schools in the fall
        date: 2020-09-03
       words: 2475
      flesch: 27
     summary: School children are nonetheless anticipated to contribute to the community transmission of SARS-CoV-2 through their large numbers of daily social contacts, some of which are intergenerational, with older age groups where the risk for more severe illness is increased. Primary or elementary school children aged 6-11 years were less likely to transmit the virus compared with high school aged children who could transmit the virus as efficiently as adults.
    keywords: children; coronavirus; covid-19; disease; sars; school; transmission
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        item: #1492 of 7819
          id: cord-267612-1h7xpkbe
      author: Lipsker, Dan
       title: A chilblain epidemic during the COVID-19 pandemic. A sign of natural resistance to SARS-CoV-2?
        date: 2020-06-06
       words: 516
      flesch: 24
     summary: A sign of natural resistance to SARS-CoV-2? Dan Lipsker 1,2 , MD, PhD Since the start of the COVID-19 pandemic, epidemics of chilblains or chilblain-like acral lesions have been reported in the social media, the general press and the medical literature in Italy, Spain, the UK and France (1) (2) (3) (4) (5) . The great majority of the cases we observed and those reported in the literature share the following common features: -lesions were of sudden onset in young patients without a previous history of chilblains in most of them and they were not necessarily triggered by exposure to cold; -those young patients were otherwise asymptomatic or pauci-symptomatic and only a few had mild clinical signs compatible with COVID-19; -none of them had pneumonia or severe manifestations of COVID-19; -clinical signs of COVID-19 or contact with infected persons occurred a few days to one month before chilblains; -SARS-CoV-2 infection could be demonstrated by nasopharyngeal swab or by serology only in very limited number of patients.
    keywords: covid-19
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        item: #1493 of 7819
          id: cord-267618-ots27qks
      author: Molliqaj, Granit
       title: How Neurosurgeons Are Coping with COVID-19 and How It Impacts Our Neurosurgical Practice: Report from Geneva University Medical Center
        date: 2020-05-08
       words: 1199
      flesch: 48
     summary: The fact that we have assigned 50% of our residents to COVID-19 units does not prevent us from ensuring that they maintain a minimum level of training. However, as the technical platform in private clinics does not allow for complex cranial surgery, some of our complex surgeries, such as ruptured arteriovenous cerebral malformations or ruptured aneurysms, had to be transferred to other Swiss university hospitals, which were and are less impacted by the COVID-19 situation.
    keywords: covid-19; geneva; health; world
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        item: #1494 of 7819
          id: cord-267621-oc8bw7ft
      author: Kevorkian, Jean-Philippe
       title: Early short-course corticosteroids and furosemide combination to treat non-critically ill COVID-19 patients: An observational cohort study
        date: 2020-09-01
       words: 1205
      flesch: 29
     summary: Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial COVID-19: consider cytokine storm syndromes and immunosuppression Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury The effect of corticosteroid treatment on patients with coronavirus infection: a systematic review and meta-analysis Fluid management in ARDS Dexamethasone in hospitalized patients with COVID-19-Preliminary Report Low-dose corticosteroid therapy does not delay viral clearance in patients with COVID-19 Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study COVID-19 in patients with heart failure: the new and the old epidemic Troponin Ic high-sensitivity (ng/mL) 18 11 In COVID-19 patients, viral shedding is elevated early then declines.
    keywords: corticosteroids; covid-19; furosemide; patients
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        item: #1495 of 7819
          id: cord-267624-v6e9zzfg
      author: Rinkel, L. A.
       title: Impact of the COVID-19 outbreak on acute stroke care
        date: 2020-07-20
       words: 2543
      flesch: 47
     summary: However, since stroke patients in our region rarely are presented through outpatient clinics, the influence of suspension of outpatient services on acute stroke care is probably minimal. There was no change in the proportion of stroke patients treated with intravenous thrombolysis (28% vs. 30%, p = 0.58) or endovascular thrombectomy (11% vs 12%, p = 0.82) or associated treatment times.
    keywords: care; covid-19; outbreak; patients; period; stroke
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        item: #1496 of 7819
          id: cord-267645-39sao4nu
      author: De Felice, Francesca
       title: A snapshot on radiotherapy for head and neck cancer patients during the COVID-19 pandemic: a survey of the Italian Association of Radiotherapy and Clinical Oncology (AIRO) head and neck working group
        date: 2020-10-06
       words: 2502
      flesch: 40
     summary: In case of COVID-19 positive HNC patients (20.9%), all specialists postponed the beginning of radiotherapy after negativization of swab test. Two sections exploited changes in general management of HNC patients and different HNC primary tumors, addressing specific statements from ASTRO ESTRO consensus statement as well.
    keywords: cancer; cases; covid-19; hnc; management; patients; treatment
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        item: #1497 of 7819
          id: cord-267690-g0kesgjm
      author: Mueller, Sarina K.
       title: Considerations for Continuing Semielective and Emergency Otolaryngological Procedures During the COVID-19 Pandemic
        date: 2020-09-07
       words: 2809
      flesch: 47
     summary: All semielective surgery patients were screened preoperatively for COVID-19 symptoms and COVID-19 associated risk factors (contact with confirmed COVID-19 patients, stay in one of the international risk areas within the last 14 days) according to the daily updated recommendations of the Robert Koch Institute-a federal institute within the German Federal Ministry of Health. We consider a posttest probability of below 5% sufficiently low to continue operating on semielective patients.
    keywords: covid-19; emergency; health; patients; sars; surgeries; surgery
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        item: #1498 of 7819
          id: cord-267691-whn49c79
      author: Rooney, L.
       title: ‘Policing’ a pandemic: Garda wellbeing and COVID-19
        date: 2020-05-28
       words: 3506
      flesch: 35
     summary: Furthermore, research not only indicates that heighted levels of psychological distress are an occupational hazard associated with the law enforcement profession, but that members of the Garda Síochána feel their mental health needs are largely unmet by their organisation. The duties of the Garda Síochána stretch far beyond 'traditional' modes of policing, such as solving crime and law enforcement.
    keywords: covid-19; garda; health; officers; pandemic; police; support; síochána
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        item: #1499 of 7819
          id: cord-267697-b6cg5j32
      author: Zhao, Kedong
       title: Negligible risk of the COVID-19 resurgence caused by work resuming in China (outside Hubei): a statistical probability study
        date: 2020-03-27
       words: 724
      flesch: 51
     summary: Under the above assumptions, we collected the data of new COVID-19 cases in the past 14 days (from 28 February to 12 March; see Supplementary Table S1) in each area and also the population size and numbers of enterprises in 2019. Here, we estimated the probability of COVID-19 resurgence caused by work resuming in typical provinces/cities and found that such probability is very limited (<5% for all the regions except Beijing).
    keywords: china; covid-19
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        item: #1500 of 7819
          id: cord-267699-h7ftu3ax
      author: MacIntyre, C. Raina
       title: A RAPID SYSTEMATIC REVIEW OF THE EFFICACY OF FACE MASKS AND RESPIRATORS AGAINST CORONAVIRUSES AND OTHER RESPIRATORY TRANSMISSIBLE VIRUSES FOR THE COMMUNITY, HEALTHCARE WORKERS AND SICK PATIENTS
        date: 2020-04-30
       words: 4129
      flesch: 44
     summary: The five available studies of mask use by sick patients suggest a benefit, but are much smaller trials than the community trials, two without clinical endpoints, and with less certainty around the findings (34) (35) (36) (37) . They also found no evidence of efficacy of hand hygiene or health education, suggesting mask use is more protective than hand hygiene.
    keywords: healthcare; influenza; masks; respirators; trials; use; workers
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        item: #1501 of 7819
          id: cord-267713-i75e5vtw
      author: Lim, Andy
       title: An International Report on the Adaptations of Rapid Transient Ischaemic Attack Pathways During the COVID-19 Pandemic
        date: 2020-08-18
       words: 2897
      flesch: 46
     summary: The key findings were: (1) all participating centres remained operational, (2) change in assessment to telephone and/or video-enabled visits; (3) change in type of vascular imaging investigations, First, the fact that all participating centres reported an active status suggests that the commitment that health services have made to redirecting TIA patients to rapid and/or outpatient pathways is significant. Third, it remains uncertain how the COVID era has altered the patient demographics and number of patients referred for TIA clinic evaluation.
    keywords: attack; centres; clinic; covid-19; pandemic; pathways; patients; stroke; tia
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        item: #1502 of 7819
          id: cord-267735-y3832u9e
      author: Sun, Wuping
       title: Management of Immunity Alteration-Induced Chronic Pain During the Coronavirus Disease-2019 (COVID-19) Pandemic
        date: 2020-09-24
       words: 3077
      flesch: 27
     summary: Strengthening the patient's confidence could be necessary to relieve psychological stress in chronic pain patients during the COVID-19 outbreak. Chronic pain patients have received limited treatment and discounted services during the COVID-19 outbreak due to limit the spread of SARS-CoV-2 infection.
    keywords: covid-19; et al; individuals; infection; pain; patients; sars; treatment
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        item: #1503 of 7819
          id: cord-267748-uzt8a5nx
      author: Shiohara, Tetsuo
       title: Comment on “Drug reaction with eosinophilia and systemic symptoms syndrome in a patient with COVID‐19”: Involvement of herpesvirus reactivations and adverse drug reactions in diverse cutaneous manifestations and overall disease severity of COVID‐19
        date: 2020-09-24
       words: 926
      flesch: 27
     summary: key: cord-267748-uzt8a5nx authors: Shiohara, Tetsuo; Mizukawa, Yoshiko title: Comment on “Drug reaction with eosinophilia and systemic symptoms syndrome in a patient with COVID‐19”: Involvement of herpesvirus reactivations and adverse drug reactions in diverse cutaneous manifestations and overall disease severity of COVID‐19 date: 2020-09-24 journal: J Eur Acad Dermatol Venereol DOI: 10.1111/jdv.16959 sha: doc_id: 267748 cord_uid: uzt8a5nx We have read with great interest the publication by Herman, et al., which reported occurrence of drug reaction with eosinophilia and systemic symptoms (DRESS), also known as drug‐induced hypersensitivity syndrome (DiHS), in a COVID‐19 patient:(1) the patient developed DiHS/DRESS 17~18 days after starting azithromycin and hydroxychloroquine. We have read with great interest the publication by Herman, et al., which reported occurrence of drug reaction with eosinophilia and systemic symptoms (DRESS), also known as drug-induced hypersensitivity syndrome (DiHS), in a COVID-19 patient: 1 the patient developed DiHS/DRESS 17~18 days after starting azithromycin and hydroxychloroquine.
    keywords: covid-19; dihs; drug
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        item: #1504 of 7819
          id: cord-267782-4pjfnund
      author: Lan, Fan-Yun
       title: Association between SARS-CoV-2 infection, exposure risk and mental health among a cohort of essential retail workers in the USA
        date: 2020-10-30
       words: 5060
      flesch: 42
     summary: This is the first study to demonstrate the significant asymptomatic infection rate, exposure risks and associated psychological distress of grocery retail essential workers during the pandemic, which supports the policy recommendations that employers and government officials should take actions on implementing preventive strategies and administrative arrangements, such as methods to reduce interpersonal contact, repeat and routine SARS-CoV-2 employee testing, to ensure the health and safety of essential workers. key: cord-267782-4pjfnund authors: Lan, Fan-Yun; Suharlim, Christian; Kales, Stefanos N; Yang, Justin title: Association between SARS-CoV-2 infection, exposure risk and mental health among a cohort of essential retail workers in the USA date: 2020-10-30 journal:
    keywords: anxiety; cov-2; covid-19; depression; employees; exposure; health; sars; study; testing; workers
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        item: #1505 of 7819
          id: cord-267815-4fw7xgnt
      author: Peña, Juan A.
       title: A Survey of Labor and Delivery Practices in New York City during the COVID-19 Pandemic
        date: 2020-06-09
       words: 2896
      flesch: 49
     summary: Fetal testing in COVID-19 patients varied. There was less consensus on antepartum fetal surveillance in COVID-19 patients.
    keywords: cov-2; covid-19; pandemic; patients; sars; sites
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        item: #1506 of 7819
          id: cord-267856-t3ksa18w
      author: Funk, Colin D.
       title: A Novel Strategy to Mitigate the Hyperinflammatory Response to COVID-19 by Targeting Leukotrienes
        date: 2020-08-06
       words: 4358
      flesch: 30
     summary: Several drug candidates have already been ruled out as effective agents, based on early trial results (e.g., hydroxychloroquine), with only two (the antiviral remdesivir and the synthetic glucocorticoid dexamethasone) showing partial efficacy in randomized clinical trials (Goldman et al., 2020; Recovery Collaborative Group, 2020; Wang et al., 2020) . This pricing is still much less than a 5-day course of the antiviral drug remdesivir (over $3,000 USD) 6 , which has shown limited efficacy to date (Goldman et al., 2020) .
    keywords: cells; cov-2; covid-19; disease; et al; leukotriene; montelukast; patients; receptor; sars; vascular; zileuton
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        item: #1507 of 7819
          id: cord-267874-k6tmu5gi
      author: Ramírez, Ivan J.
       title: COVID-19 Emergence and Social and Health Determinants in Colorado: A Rapid Spatial Analysis
        date: 2020-05-29
       words: 5181
      flesch: 49
     summary: Table 1 shows the change in COVID-19 incidence rates between March 14 and April 8 expressed as ratios. Using Pearson's correlation, the analysis showed that COVID-19 incidence rates were positively associated with per capita income (r = 0.32, p-value = 0.009) and multiple unit structures (r = 0.40, p-value = 0.001), and negatively associated with mobile homes (r = −0.31, p-value = 0.014).
    keywords: april; cases; colorado; counties; covid-19; deaths; health; incidence
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        item: #1508 of 7819
          id: cord-267907-zbsbqj9o
      author: Brown, Samantha M.
       title: Stress and Parenting during the Global COVID-19 Pandemic
        date: 2020-08-20
       words: 7982
      flesch: 38
     summary: Manual The effects of economic hardship on family relationships among African American, Latino, and Euro-American families Ethnic differences in family stress processes among African-Americans and Black Carribeans The dark side of inclusion: Undesired acceptance increases aggression Stress exposure and depression in disadvantaged women: The protective effects of optimism and perceived control ADHD and parental psychological distress: Role of demographics, child behavioral characteristics, and parental cognitions Loneliness matters: A theoretical and empirical review of consequences and mechanisms head: STRESS, PARENTING, AND COVID-19 Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: A web-based cross-sectional survey Relations between parenting stress, parenting style, and child executive functioning for children with ADHD or autism Racial and ethnic residential segregation and household structure: A research note Examining dynamic links between perceived control and health: Longitudinal evidence for differential effects in midlife and old age The SARS (Severe Acute Respiratory Syndrome) pandemic in Hong Kong: Effects on the subjective wellbeing of elderly and younger people Cognitive and coping processes in emotion A cumulative risk model of child physical maltreatment head: STRESS, PARENTING, AND COVID-19 33 potential: Findings from a community-based study The association between perceived provider discrimination, health care utilization, and health status in racial and ethnic minorities Protective factors among families with children at risk of maltreatment: Follow up to early school years A test of missing completely at random for multivariate data with missing values Familial financial stress and child internalizing behaviors: The roles of caregivers' maltreating behaviors and social services Socioeconomic inequalities in depression: A meta-analysis The psychological impact of COVID-19 pandemic in Italy: A lesson for mental health prevention in the first severely hit European city Maternal variations in stress reactivity: Implications for harsh parenting practices with very young children Predictors of parenting stress for abusive and nonabusive mothers The Child Abuse Potential Inventory: Manual Prediction and explanation of child abuse The correlation between stress and economic crisis: A systematic review The brief Child Abuse Potential Inventory: Development and validation Qualitative methods in social work research Perceived control and mindfulness: Implications for clinical practice Child maltreatment as a function of cumulative family risk: Findings from the intensive family preservation program Barriers to care among racial/ethnic groups under managed care Mental health before and during the COVID-19 pandemic: A longitudinal probability sample survey of the UK population The Lancet Psychiatry. Because emerging research has shown that families of diverse racial and ethnic identities may be disproportionately impacted by the COVID-19 pandemic, chi-square and one-way ANOVA analyses were conducted to examine whether there were racial and ethnic differences in COVID-19 risk factors, mental health risk factors, and protective factors.
    keywords: abuse; child; covid-19; factors; families; health; parenting; potential; risk; stress
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        item: #1509 of 7819
          id: cord-267923-0z175ysz
      author: Li, Jingwen
       title: Emergent hospital reform in response to outbreak of COVID-19
        date: 2020-05-06
       words: 804
      flesch: 40
     summary: Eighth, we explored building regional coalition, a network of tertiary care centers and community hospitals, to coordinate other hospitals and health systems for transferring the COVID-19 patients. During a long period starting from Jan, 2020, shortage of hospital beds for COVID-19 was a serious public concern in Wuhan.
    keywords: covid-19; hospital; patients
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        item: #1510 of 7819
          id: cord-267947-dnv2xl0h
      author: Gornet, Jean-Marc
       title: What do surgeons need to know about the digestive disorders and paraclinical abnormalities induced by COVID-19?
        date: 2020-04-24
       words: 3752
      flesch: 37
     summary: Even though these data remain highly fragmentary, digestive cancer patients are probably significantly at risk of COVID-19 infection, particularly those currently undergoing intravenous chemotherapy, who risk contamination during their care pathway (repeated hospitalizations, imaging examinations and blood tests in medicalized structures…). It should nonetheless be noted that notwithstanding the presence of the ACE2 receptor in the cholangiocytes, the patients did not present with intrahepatic cholestasis, which is associated with the virus (absence of elevated Gamma Gt and PAL in study patients without preexisting liver disease).
    keywords: covid-19; data; diarrhea; digestive; infection; patients; risk; symptoms
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        item: #1511 of 7819
          id: cord-267971-xgwmda8e
      author: Tan, Shing Cheng
       title: Clinical and epidemiological characteristics of Coronavirus Disease 2019 (COVID-19) patients
        date: 2020-04-07
       words: 2857
      flesch: 51
     summary: This paper aimed to pool the available data to provide a more complete picture of the characteristics of COVID-19 patients. Conclusions: Clinical and epidemiological characteristics of COVID-19 patients were mostly heterogeneous and non-specific.
    keywords: covid-19; data; disease; license; patients; preprint
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        item: #1512 of 7819
          id: cord-267996-5l9shks8
      author: Tysiąc-Miśta, Monika
       title: The Attitudes and Professional Approaches of Dental Practitioners during the COVID-19 Outbreak in Poland: A Cross-Sectional Survey
        date: 2020-06-30
       words: 6345
      flesch: 52
     summary: The direct result of the overwhelming fear, confusion and anxiety among dental staff, which was amplified by the high perception of COVID-19 contraction risk, was a significant reduction in dental clinical practice in Poland. Our secondary aim was to assess the decrease in the number of dental patients admitted in April 2020 in comparison with that in the time before the beginning of the pandemic in Poland in March 2020.
    keywords: covid-19; dental; dentists; group; health; pandemic; ppe; practice; test; work
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        item: #1513 of 7819
          id: cord-268011-q24zsyn4
      author: Rakshit, Bijoy
       title: When China sneezes, middle east states get the cold
        date: 2020-06-15
       words: 1571
      flesch: 54
     summary: Middle East economies are exposed to China through a robust supply chain, tourism, and other travel-related services. Finally, we explain the case of Middle East states and demonstrate the pathways that explain the economic repercussion of this global pandemic on the region.
    keywords: china; covid-19; east; middle
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        item: #1514 of 7819
          id: cord-268040-6i0bmnee
      author: Dean, Elizabeth
       title: Translating COVID-19 Evidence to Maximize Physical Therapists’ Impact and Public Health Response
        date: 2020-06-26
       words: 2049
      flesch: 28
     summary: COVID-19 Advice to the public Diabetes is a risk factor for the progression and prognosis of COVID -19 Anti-inflammatory diet in clinical practice: A review Health competency standards in physical therapist practice How not to die Food based dietary patterns and chronic disease prevention Istituto Superiore di Sanità. ARDS is well familiar to physical therapists in intensive care units.
    keywords: care; covid-19; health; lifestyle; ncds; patients; profession
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        item: #1515 of 7819
          id: cord-268049-7xqln70d
      author: Montrief, Tim
       title: COVID-19 respiratory support in the emergency department setting
        date: 2020-08-08
       words: 5201
      flesch: 38
     summary: [24] [25] [26] HFNC is an emerging support modality for patients with COVID-19 and has been associated with increased survival in COVID-19 patients when compared to either NIV or invasive mechanical ventilation. 38 International guidelines on the use of NIV for COVID-19 patients vary, with many guidelines recommending against the routine use of NIV due to increased risk of virus aerosolization and unproven utility in patients with ARDS.
    keywords: airway; covid-19; failure; intubation; management; niv; oxygen; patients; risk; sars
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        item: #1516 of 7819
          id: cord-268058-1ry3z2vb
      author: Di, Biao
       title: Identification and validation of predictive factors for progression to severe COVID-19 pneumonia by proteomics
        date: 2020-10-03
       words: 1858
      flesch: 39
     summary: To further identify severe COVID-19 predictive factor proteins, we designed an iterative model building approach on the proteomics data to search for an optimal combination of proteins for prediction of severe COVID-19 patients ( Supplementary Fig. 9a ). [Mn], mitochondrial (SOD2), thymosin beta-4 (TMSB4X), and tumor necrosis factor receptor superfamily member 17 (TNFRSF17), are only found in severe patients while the expression of such those 10 proteins are either nonsignificantly different or downregulated in moderate patients as compared to controls ( Supplementary Fig. 4) .
    keywords: covid-19; fig; group; oaf; patients; proteins
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        item: #1517 of 7819
          id: cord-268062-f03acrrd
      author: Weaver, Michael
       title: COVID-19 and Jaundice
        date: 2020-10-08
       words: 771
      flesch: 38
     summary: Furthermore, hepatic involvement in COVID-19 patients has been observed with biochemical elevations in liver chemistries in 10-53% of patients and jaundice observed in 5-18% of patients 1 which is thought to be multifactorial due to hepatic injury resulting from COVID-19 associated sepsis and hypotension, accompanying cytokine storm, as well as drug induced liver injury from a variety of medications used to treat COVID-19 infection. COVID-19 infection has been shown to affect the gastrointestinal system acutely with a variety of symptoms including nausea, vomiting, diarrhea, abdominal pain.
    keywords: biliary; covid-19; infection
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        item: #1518 of 7819
          id: cord-268064-ljjcyv92
      author: Zhao, Guolian
       title: A comparative study of the laboratory features of COVID‐19 and other viral pneumonias in the recovery stage
        date: 2020-07-21
       words: 1762
      flesch: 38
     summary: At the clinical recovery stage, severe patients with COVID-19 had lower levels of total proteins (P < .05), albumin (P < .01), superoxide dismutase (SOD, P < .01), and lymphocytes (P < .01); higher levels of neutrophils (P < .05), C-reactive protein (CRP, P < .01), and fibrinogen degradation products (FDP, P < .05); and a higher erythrocyte sedimentation rate (ESR, P < .01) than moderate patients (Table 3) Additionally, COVID-19 patients were more likely to exhibit a nonproductive cough, fatigue, gastrointestinal symptoms, and ground-glass opacities than H1N1 patients.
    keywords: covid-19; laboratory; patients; recovery; stages; study
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        item: #1519 of 7819
          id: cord-268065-mxvbbkc4
      author: Wei, Maoti
       title: Epidemiology of Coronavirus Disease 2019 (COVID-19) Caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
        date: 2020-05-18
       words: 4411
      flesch: 51
     summary: Although the data of SARS cases were analyzed by epidemiological models, the results showed that the spread of SARS infection was not supported by aerosols, but by droplets. Peoples Government of Hubei Province website Genetic evolution analysis of 2019 novel coronavirus and coronavirus from other species Wuhan seafood market may not be source of novel virus spreading globally Kraemer M. epidemiological data from the ncov-2019 outbreak: early descriptions from publicly available data Estimates of the clock and TMRCA for 2019-nCoV based on 27 genomes Importation and human-tohuman transmission of a novel coronavirus in Vietnam A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Determining SARS sub-clinical infection: a longitudinal seroepidemiological study in recovered SARS patients and controls after an outbreak in a general hospital Viral load dynamics and disease severity in patients infected with SARS-CoV-2 in Zhejiang province Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study A novel coronavirus outbreak of global health concern Transmission of COVID-19 infection from an asymptomatic contact in Germany Presymptomatic transmission of SARS-CoV-2 -Singapore Super-spreading events of MERS-CoV infection Nowcasting and forecasting the potential domestic and international spread of the COVID-19 outbreak originating in Wuhan, China: a modeling study The presence of SARS-CoV-2 RNA in the feces of COVID-19 patients First case of 2019 novel coronavirus in the United States Modelling the epidemic trend of the 2019 novel coronavirus outbreak in China Coronavirus disease (COVID-2019) situation reports Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Epidemiological characteristics of confirmed avian influenza A (H7N9) cases in mainland China-A Preliminary Report]
    keywords: cases; china; covid-19; epidemic; infection; market; sars; transmission
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        item: #1520 of 7819
          id: cord-268075-kbislbx0
      author: Song, Limin
       title: Cardiovascular Changes in Patients With COVID-19 From Wuhan, China
        date: 2020-09-02
       words: 4063
      flesch: 40
     summary: Further evidence is needed to evaluate the safety and potential effects of ACEIs/ARBs in COVID-19 patients with hypertension. Autopsy of COVID-19 patients found interstitial mononuclear inflammatory infiltrates in the heart tissue and epicardial edema (35) .
    keywords: covid-19; data; hypertension; injury; patients; sars; study
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        item: #1521 of 7819
          id: cord-268084-pttsahkb
      author: Vest, N. A.
       title: Prison population reductions and COVID-19: A latent profile analysis synthesizing recent evidence from the Texas state prison system
        date: 2020-09-10
       words: 1809
      flesch: 50
     summary: Profile 1 (88 out of 103 prisonsdashed black line in Figure 2) , low outbreak facilities, was characterized by prisons with a low number of incarcerated resident cases, a low number of incarcerated resident deaths, and a low number of prison staff cases. Profile 2 (5 out of 105 prisonsblack line in Figure 2) , high death facilities, was characterized by prisons with a moderate number of incarcerated resident cases, a very high level of incarcerated resident deaths, and a high level of prison staff cases.
    keywords: cases; covid-19; prison; profile
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        item: #1522 of 7819
          id: cord-268085-vpzrk8u7
      author: Mandal, Amrendra
       title: Gastrointestinal Manifestations in COVID-19 Infection and Its Practical Applications
        date: 2020-06-21
       words: 3115
      flesch: 36
     summary: In a study that analyzed COVID-19 patients, 39 (53.4%) were found to be positive for COVID-19 in stool, with a duration of positive stool ranging between 1 and 12 days However, the histopathological study of liver tissue from COVID-19 patients did not show viral inclusions in the liver specimens [20] .
    keywords: coronavirus; covid-19; infection; liver; patients; sars; symptoms
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        item: #1523 of 7819
          id: cord-268112-zk8z8z4i
      author: Zhu, Linnan
       title: Single-cell sequencing of peripheral blood mononuclear cells reveals distinct immune response landscapes of COVID-19 and influenza patients
        date: 2020-07-19
       words: 3261
      flesch: 31
     summary: We observed increase of plasma cells in both COVID-19 and IAV patients, and XAF1-, TNF- and FAS-induced T cell apoptosis in COVID-19 patients. XBP1 is a positively-acting transcription factor in the 189 CREB-ATF family that is expressed at a high amounts in plasma cells, and is crucial 190 for increasing protein synthesis in plasma cells (Shaffer et al., 2004) .
    keywords: apoptosis; cells; covid-19; expression; figure; genes; patients; protein; regulation; response
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        item: #1524 of 7819
          id: cord-268117-5xhc3h0z
      author: Merzon, E.
       title: Low plasma 25(OH) vitamin D3 level is associated with increased risk of COVID-19 infection: an Israeli population-based study
        date: 2020-07-03
       words: 3143
      flesch: 46
     summary: Notably, a recent study from the UK (33-35) that included 449 subjects (from the UK Biobank) with confirmed COVID-19 infection did not find an association between vitamin D metabolite concentration and the risk of viral infections (47) as well as COVID-19 infection (5, 7, (9) (10) (11) (12) (13) (14) (15) (16) 20, (32) (33) (34) (35) (36) (37) (38) (39) (40) (41) (42) (43) (44) . key: cord-268117-5xhc3h0z authors: Merzon, E.; Tworowski, D.; Gorohovski, A.; Vinker, S.; Golan Cohen, A.; Green, I.; Frenkel Morgenstern, M. title: Low plasma 25(OH) vitamin D3 level is associated with increased risk of COVID-19 infection: an Israeli population-based study date: 2020-07-03 journal: nan DOI: 10.1101/2020.07.01.20144329 sha: doc_id: 268117 cord_uid: 5xhc3h0z Aim: To evaluate associations of plasma 25(OH)D status with the likelihood of coronavirus disease (COVID-19) infection and hospitalization.
    keywords: covid-19; license; medrxiv; medrxiv preprint; perpetuity; preprint
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        item: #1525 of 7819
          id: cord-268126-u9z1rir1
      author: Ranisch, Robert
       title: Digital contact tracing and exposure notification: ethical guidance for trustworthy pandemic management
        date: 2020-10-21
       words: 5331
      flesch: 40
     summary: 268126 cord_uid: u9z1rir1 There is growing interest in contact tracing apps (CT apps) for pandemic management. In this paper, we illustrate the complexity and multiplicity of the ethical considerations by presenting an ethical framework for a responsible design and implementation of CT apps.
    keywords: apps; contact; covid-19; data; digital; health; measures; pandemic; public; tracing
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        item: #1526 of 7819
          id: cord-268135-77emtyen
      author: Moghadam, Vahid Damanpak
       title: Letter to the Editor: Additional Recommendations before Intubation of COVID-19 Patients
        date: 2020-06-30
       words: 399
      flesch: 28
     summary: Therefore, as a resolve of this problem and preventing cough in patients infected with COVID-19, we propose injecting intravenous lidocaine or dexmedetomidine before administrating tracheal intubation. The systematic review and meta-analysis articles published by Clivio et al. and Tung et al. confirmed our statement, because they declared that intravenous lidocaine dose dependently prevents intubation, extubation, and opioid-induced cough in adults, and the suggested dose by the authors for achieving this goal was 0.5-2.0 mgjkg lntravenously.
    keywords: intubation; patients
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        item: #1527 of 7819
          id: cord-268140-s5lailkp
      author: Atal, Shubham
       title: IL-6 Inhibitors in the Treatment of Serious COVID-19: A Promising Therapy?
        date: 2020-06-13
       words: 5184
      flesch: 36
     summary: Furthermore, tissue necrosis and interstitial macrophages and monocyte infiltrations in the lungs, heart and gastrointestinal mucosa have been demonstrated in postmortem pathology in COVID-19 patients [25, 31] . It has been proposed that early diagnosis of CRS in COVID-19 patients through screening tools like the H-score used for HLH, and prompt immunomodulation with IL-6 inhibitors may be beneficial, as in HLH [37] .
    keywords: coronavirus; covid-19; drugs; evidence; il-6; inhibitors; lung; patients; sars; tocilizumab; treatment
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        item: #1528 of 7819
          id: cord-268145-0sv6fdtj
      author: Long, Brit
       title: Just the Facts: What are the roles of oxygen escalation and noninvasive ventilation in COVID-19?
        date: 2020-05-13
       words: 1556
      flesch: 48
     summary: What is the role of noninvasive positive pressure ventilation (NIPPV) measures for the patient with suspected or confirmed COVID-19? NIPPV other than high-flow nasal cannula may have a role in the management of hypoxemic COVID-19 patients. What is high flow nasal cannula, and how should it be started? High-flow nasal cannula therapy is a system that delivers heated (37°C) and humidified (100% relative humidity) oxygen at concentrations ranging from 21%-100% at flow rates reaching 60 liters per minute.
    keywords: cannula; flow; nasal; patients
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        item: #1529 of 7819
          id: cord-268176-tb12txdf
      author: Garcia de Avila, Marla Andréia
       title: Children’s Anxiety and Factors Related to the COVID-19 Pandemic: An Exploratory Study Using the Children’s Anxiety Questionnaire and the Numerical Rating Scale
        date: 2020-08-09
       words: 5789
      flesch: 52
     summary: Children keeping social distance without their parents had higher levels of anxiety than children with both parents at home (p = 0.029). Children whose guardians were among the youngest and with the lowest levels of education among the participants had higher CAQ scores than children whose guardians were older and more educated (for postgraduate B = 0.996, for university graduate B = 0.995, p < 0.05; Table 4 ).
    keywords: anxiety; caq; children; covid-19; guardians; nrs; scores; study
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        item: #1530 of 7819
          id: cord-268179-bmtfanax
      author: Fan, Jingchun
       title: Bibliometric Analysis on COVID-19: A Comparison of Research Between English and Chinese Studies
        date: 2020-08-14
       words: 4949
      flesch: 40
     summary: There are 252 institutions from 32 countries published COVID-19 related English papers. Methods: Publications on COVID-19 research were retrieved from both English and Chinese databases.
    keywords: analysis; authors; china; chinese; covid-19; english; journals; keywords; papers; publications
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        item: #1531 of 7819
          id: cord-268190-r428y2j9
      author: Vivanti, Alexandre J.
       title: Post-natal follow-up for women and neonates during the COVID-19 pandemic: French National Authority for Health recommendations
        date: 2020-05-11
       words: 2966
      flesch: 42
     summary: Group (GPIP) do not currently recommend separation of mother and child and do not contraindicate breastfeeding 10 . -Postnatal monitoring of mother and child by the midwife in liaison with the referring obstetrical team.
    keywords: child; covid-19; health; mother; newborn
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        item: #1532 of 7819
          id: cord-268206-ino9srb6
      author: Hamed, Manal A.
       title: An overview on COVID-19: reality and expectation
        date: 2020-06-01
       words: 6090
      flesch: 35
     summary: However, there is no clear evidence that the BCG vaccine protects people against infection with COVID-19 virus. In a study involving patients with pandemic influenza (H1N1) and SARS virus, treatment of severe infection with convalescent plasma was associated with reduced respiratory viral load, serum cytokine response, and mortality (Cheng et al. 2005; Hung et al. 2011) .
    keywords: angiotensin; chloroquine; coronavirus; cov-2; covid-19; disease; enzyme; et al; infection; novel; obesity; patients; protein; sars; treatment
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        item: #1533 of 7819
          id: cord-268247-psrijhg2
      author: Ullah, Waqas
       title: As the COVID-19 pandemic drags on, where have all the STEMIs gone?
        date: 2020-05-31
       words: 981
      flesch: 43
     summary: [2] These findings are particularly concerning given that COVID-19 itself can be a cause of STEMI due to microthrombi, cytokine storm, coronary spasm, or direct endothelial injury, furthermore acute coronary syndrome occurring in COVID-19 patients has been associated with a worse prognosis. [7] More recently, the Society of Cardiovascular Angiography and Intervention (SCAI) recommendations favored continuation of the current standard of care (percutaneous intervention) in COVID-19 patients, though recognize that this may change if hospital systems become further overwhelmed.
    keywords: care; covid-19; patients; stemi
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        item: #1534 of 7819
          id: cord-268293-u5r2id8i
      author: Hess, Robert G.
       title: Shared Governance During a Pandemic
        date: 2020-07-11
       words: 1806
      flesch: 48
     summary: If shared governance councils are to be used to deal with emergent issues, have resources ready to continue its customary, necessary work. At other hospitals, clinical nurses began to wonder what happened to shared governance.
    keywords: covid-19; governance; hospitals; nurses; pandemic
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        item: #1535 of 7819
          id: cord-268306-wreifhzl
      author: Leitao, Darren Jonathan
       title: Pediatric rigid bronchoscopy and foreign body removal during the COVID-19 pandemic: case report
        date: 2020-09-14
       words: 3149
      flesch: 45
     summary: key: cord-268306-wreifhzl authors: Leitao, Darren Jonathan; Jones, Jodi L. P. title: Pediatric rigid bronchoscopy and foreign body removal during the COVID-19 pandemic: case report date: 2020-09-14 journal: J Otolaryngol Head Neck Surg DOI: 10.1186/s40463-020-00464-z sha: doc_id: 268306 cord_uid: wreifhzl The patient was taken the operating room for rigid bronchoscopy and foreign body removal.
    keywords: airway; body; bronchoscopy; covid-19; equipment; operating; patient; room
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        item: #1536 of 7819
          id: cord-268324-86a0n0dc
      author: Charitos, Ioannis A
       title: Special features of SARS-CoV-2 in daily practice
        date: 2020-09-26
       words: 6120
      flesch: 38
     summary: Current studies are investigating the relationship between different variables and the risk of death of COVID-19 patients hospitalized for pneumonia. COVID-19 patients are often very complex and require a multidisciplinary medical team which includes at least the following specialists: emergency doctor, pulmonologist, infectious disease specialist, critical care physician, and medical laboratory technician [72]
    keywords: cases; coronavirus; cov-2; covid-19; disease; health; infection; management; patients; pneumonia; risk; sars; symptoms; treatment; use; world
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        item: #1537 of 7819
          id: cord-268329-apl6n6jl
      author: Antunes, Douglas Eulálio
       title: Will cases of leprosy reaction increase with COVID-19 infection?
        date: 2020-07-17
       words: 1509
      flesch: 36
     summary: In both reactions, we warn of the possible effect that COVID-19 infection may have on the number of cases of these immunological events because the presence of infection is an important risk factor for triggering leprosy reactions [8] . These precautions will aid prevention of the spread of COVID-19 infection-and its severe manifestations, including leprosy reactions. Evaluation and Treatment Coronavirus (COVID-19)
    keywords: covid-19; disease; leprosy; patients; reactions
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        item: #1538 of 7819
          id: cord-268330-mo5myrz4
      author: Gentile, Pietro
       title: Adipose-derived stromal stem cells (ASCs) as a new regenerative immediate therapy combating coronavirus (COVID-19)-induced pneumonia
        date: 2020-04-29
       words: 4633
      flesch: 42
     summary: Arch Adipose tissue-derived mesenchymal stem cell yield and growth characteristics are affected by the tissue-harvesting procedure Comparing mesenchymal stromal cells from different human tissues: bone marrow, adipose tissue and umbilical cord blood Functional studies of mesenchymal stem cells derived from adult human adipose tissue Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT) Survival after mesenchymal stromal cell therapy in steroid-refractory acute graft-versus-host disease: systematic review and meta-analysis CT-04 Safety and efficacy of allogeneic umbilical cord-derived mesenchymal stem cells (MSCs) in patients with systemic lupus erythematosus: results of an open-label phase I study Application of enhanced stromal vascular fraction and fat grafting mixed with PRP in post-traumatic lower extremity ulcers Autologous stem cells (adipose) and fibrin glue used to treat widespread traumatic calvarial defects: case report Fat graft supplemented with adipose-derived stromal cells in the rehabilitation of patients with craniofacial microsomia Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adipose-derived adult stem cells Prospective trial of adipose-derived regenerative cell (ADRC)-enriched fat grafting for partial mastectomy defects: the RESTORE-2 trial A comparative translational study: the combined use of enhanced stromal vascular fraction and platelet-rich plasma improves fat grafting maintenance in breast reconstruction Breast reconstruction with enhanced stromal vascular fraction fat grafting: what is the best method? Engineered fat graft enhanced with adipose-derived stromal vascular fraction cells for regenerative medicine: clinical, histological and instrumental evaluation in breast reconstruction An article about the impact of the Engineered Fat Graft Enhanced with Adipose-Derived Stromal Vascular Fraction Cells in breast reconstruction Concise review: adipose-derived stem cells (ASCs) and adipocyte-secreted exosomal microRNA (A-SE-miR) modulate cancer growth and promote wound repair adipocytes and breast cancer: focus on inflammation and anti-tumor immunity Adipose-derived stromal vascular fraction cells and platelet-rich plasma: basic and clinical evaluation for cell-based therapies in patients with scars on the face Impact of the different preparation methods to obtain human adipose-derived stromal vascular fraction cells (AD-SVFs) and human adipose-derived mesenchymal stem cells (AD-MSCs): enzymatic digestion versus mechanical centrifugation Intravenous hMSCs improve myocardial infarction in mice because cells embolized in lung are activated to secrete the anti-inflammatory protein TSG-6 Novel insights on systemic and brain aging, stroke, amyotrophic lateral sclerosis, and Alzheimer's disease Emerging anti-aging strategies -scientific basis and efficacy Contributions of age-related thymic involution to immunosenescence and inflammaging Aging and the immune system: the impact of immunosenescence on viral infection, immunity and vaccine immunogenicity Clinical features of patients infected with 2019 novel coronavirus in Wuhan A new mesenchymal stem cell (MSC) paradigm: polarization into a pro-inflammatory MSC1 or an Immunosuppressive MSC2 phenotype Mesenchymal stem cells: a double-edged sword in regulating immune responses Mesenchymal stromal cells: clinical challenges and therapeutic opportunities Concise review: adipose-derived stem cells (ASCs) and adipocyte-secreted exosomal microRNA (A-SE-miR) modulate cancer growth and proMote wound repair The authors would like to thank the group of Chinese investigators led by Doctor Zikuan Leng and Professor Zhao, on the precious scientific contributions published, with the possibility to promote the MSCs, ASCs infusion as COVID-19 therapy. Additionally, a higher quantity of stem cells has been observed in fat compared to bone marrow [24] .
    keywords: adipose; ascs; cells; coronavirus; covid-19; mesenchymal; mscs; patients; sars; stem; stromal; tissue
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        item: #1539 of 7819
          id: cord-268347-xz6fptol
      author: Kow, Chia Siang
       title: Pharmacotherapeutic considerations for systemic rheumatic diseases amid the COVID-19 pandemic: more questions than answers
        date: 2020-08-16
       words: 2668
      flesch: 25
     summary: Furthermore, a nationwide study in Russia found that the prevalence of systemic rheumatic diseases among COVID-19 patients admitted to ICUs with a severe course of COVID-19 was low (10 of 902 patients; 1.1%) and similar to that of the general Russian population [6] . On the other hand, IL-6 receptor inhibitors (e.g. tocilizumab and sarilumab) may be continued in selected patients, particularly those in whom cytokine storm syndrome is impending, preferably in clinical trial settings, given the potential benefit of IL-6 inhibitors in COVID-19 patients who develop an intense inflammatory state; however, conclusive evidence on their efficacy remains to be elucidated
    keywords: agents; arthritis; covid-19; disease; patients; risk
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        item: #1540 of 7819
          id: cord-268354-dq17uhzx
      author: Lastinger, Lauren T.
       title: Triage and management of the ACHD patient with COVID-19: A single center approach
        date: 2020-06-19
       words: 1784
      flesch: 37
     summary: However, ACHD patients demonstrate a higher prevalence of restrictive lung disease, acquired cardiovascular disease, and other general medical comorbidities Here we review a reasonable approach to identifying ACHD phenotypes and physiologic compensation to assist in the rapid triage of ACHD patients with known/suspected COVID-19.
    keywords: achd; covid-19; disease; patients
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        item: #1541 of 7819
          id: cord-268357-oijcqk0n
      author: Parra-Medina, Rafael
       title: Comments to: A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression
        date: 2020-07-21
       words: 721
      flesch: 35
     summary: medRxiv COVID-19: consider cytokine storm syndromes and immunosuppression Clinicopathologic and immunohistochemical findings from autopsy of patient with COVID-19 Histopathology and ultrastructural findings of fatal COVID-19 infections. In the initial autopsies in COVID-19 patients, the presence of CD68+ macrophages in lung and heart tissues [3, 4] and the presence of CD169+ macrophages in lymph node subcapsular spaces and in splenic marginal zone were reported.
    keywords: covid-19; findings; sars
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        item: #1542 of 7819
          id: cord-268389-0agwvsrv
      author: Kaminski, Monica A.
       title: Tocilizumab Therapy of COVID-19: A Comparison of Subcutaneous and Intravenous Therapies
        date: 2020-09-28
       words: 3416
      flesch: 36
     summary: More patients in the IV group received Supportive treatment with tocilizumab for COVID-19: A systematic review Clinical outcomes in COVID-19 patients treated with tocilizumab: An individual patient data systematic review Consider IL6 receptor antagonist for the therapy of cytokine storm syndrome in SARS-CoV-2 infected patients Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Risk factors of fatal outcome in hospitalized subjects with coronavirus disease 2019 from a nationwide analysis in China Detectable serum SARS-Co-V-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort Tocilizumab in patients with severe COVID-19: a retrospective cohort study Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19 Tocilizumab therapy reduced intensive care unit admissions and/or mortality in COVID-19 patients FDA approval summary: tocilizumab for treatment of chimeric antigen receptor T Cell-induced severe or life-threatening cytokine release syndrome Current concepts in the diagnosis and management of cytokine release syndrome Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19. At the time of IV tocilizumab therapy, 36 (55%) patients met grade 3 and 27 (42%)
    keywords: covid-19; patients; therapy; tocilizumab
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        item: #1543 of 7819
          id: cord-268390-npuvodd4
      author: Rehman, Aziz ul
       title: The role of primary and secondary bio-molecules in optical diagnosis of pandemic COVID-19 outbreak
        date: 2020-08-17
       words: 1279
      flesch: 36
     summary: key: cord-268390-npuvodd4 authors: Rehman, Aziz ul; Qureshi, Shahzad Ahmad title: The role of primary and secondary bio-molecules in optical diagnosis of pandemic COVID-19 outbreak date: 2020-08-17 journal: Photodiagnosis Photodyn Ther DOI: 10.1016/j.pdpdt.2020.101953 sha: doc_id: 268390 cord_uid: npuvodd4 • Primary and secondary biomarkers for optical diagnosis in of COVID-19 infected patients for early diagnosis of disease. This letter to the editor aims to introduce primary and secondary biomarkers whose reflectance, transmittance and fluorescence signals can be used for optical diagnosis of COVID-19 to the scientific community and persuade to build portable, cost effective, label free and real time optical devices for its detection.
    keywords: cov-2; covid-19; detection; devices; diagnosis; sars
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        item: #1544 of 7819
          id: cord-268424-5c6edaw8
      author: Behera, D.
       title: Tb Cotrol In India In The Covid Era
        date: 2020-08-28
       words: 1205
      flesch: 35
     summary: COVID-19: ensuring continuity of TB services in the private sector COVID-19 and TB coinfection -'Finishing touch in perfect recipe to 'severity' or 'death' COVID-19 and tuberculosis-threats and opportunities Anticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes Predicted impact of the COVID-19 pandemic on global tuberculosis deaths in 2020. This is going to lead to a reduction in quality of TB care and poor outcomes.
    keywords: covid-19; health; tuberculosis
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        item: #1545 of 7819
          id: cord-268425-xg8xnjf9
      author: DiNicolantonio, James J.
       title: Harnessing Adenosine A2A Receptors as a Strategy for Suppressing the Lung Inflammation and Thrombotic Complications of COVID-19: Potential of Pentoxifylline and Dipyridamole
        date: 2020-07-02
       words: 3896
      flesch: 30
     summary: 79 Supplemental glucosamine may likewise up-regulate the type 1 interferon responses to viruses, while exerting anti-inflammatory effects that render it protective in rodent models of sepsis and lung inflammation induced by LPS or cigarette smoke. Although PTX is known to have broad anti-inflammatory activity, it is employed primarily in the treatment of intermittent claudication; by lessening neutrophil activation, PTX renders these cells more distensible, so that they can more readily pass through narrow capillaries in affected legs.
    keywords: adenosine; cells; covid-19; dip; effects; inflammatory; lung; patients; ptx; sars
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        item: #1546 of 7819
          id: cord-268426-sz9ftmxr
      author: Maalla M’jid, Najat
       title: Hidden scars: the impact of violence and the COVID-19 pandemic on children’s mental health
        date: 2020-09-10
       words: 1808
      flesch: 51
     summary: This article outlines how the risk of children experiencing violence has increased and how the pandemic has weakened the capacity of child protection and mental health services to respond. With the use of digital technology, children around the world are providing peer-to-peer support to help ease the stress they experience, taking their activism online to share safety information among their peers and volunteering to provide support to other children in need.
    keywords: children; covid-19; health; pandemic; violence
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        item: #1547 of 7819
          id: cord-268453-87b298uk
      author: Ibáñez, Sebastián
       title: Hydroxychloroquine and chloroquine in COVID-19: should they be used as standard therapy?
        date: 2020-06-03
       words: 3503
      flesch: 42
     summary: The world health organization international clinical trials registered organization registered platform A pilot study of hydroxychloroquine in treatment of patients with common coronavirus disease-19 Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an openlabel non-randomized clinical trial Reply to Gautret et al. 2020: a Bayesian reanalysis of the effects of hydroxychloroquine and azithromycin on viral carriage in patients with Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: an observational study No evidence of rapid antiviral clearance or clinical benefit with the combination of hydroxychloroquine and azithromycin in patients with severe COVID-19 infection Hydroxychloroquine in patients with COVID-19: an open-label, randomized No evidence of clinical efficacy of hydroxychloroquine in patients hospitalized for COVID-19 infection with oxygen requirement: results of a study using routinely collected data to emulate a target trial The QT interval in patients with SARS-CoV-2 infection treated with hydroxychloroquine/ azithromycin Safety of hydroxychloroquine, alone and in combination with azithromycin, in light of rapid wide-spread use for COVID-19: a multinational, network cohort and self-controlled case series study | medRxiv Chloroquine diphosphate in two different dosages as adjunctive therapy of hospitalized patients with severe respiratory syndrome in the context of coronavirus (SARS-CoV-2) infection: preliminary safety results of a randomized, double-blinded, phase IIb clinical trial (CloroCovid-19 Study) Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations In the absence of a vaccine and specifically designed antivirals, the medical community has proposed the use of various previously available medications in order to reduce the number of patients requiring prolonged hospitalizations, oxygen therapy, and mechanical ventilation and to decrease mortality from coronavirus disease 2019 (COVID-19).
    keywords: chloroquine; coronavirus; covid-19; day; group; hcq; hydroxychloroquine; patients
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        item: #1548 of 7819
          id: cord-268455-btuzihsy
      author: de Santiago, Javier
       title: COVID-19: gynecologic cancer surgery at a single center in Madrid
        date: 2020-07-07
       words: 2970
      flesch: 42
     summary: MD Anderson Cancer Center Madrid, given its characteristics and focus on the treatment of cancer patients, can be comparatively considered as a relatively COVID-19 free center. Although there are no specific reports in cancer patients regarding the incidence of COVID-19, they are considered high risk due to older age, increased incidence of comorbidities, and lower immunity.
    keywords: cancer; covid-19; infection; pandemic; patients; study; surgery
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        item: #1549 of 7819
          id: cord-268468-036i1082
      author: Asif, Muhammad
       title: The role of biosensors in COVID-19 outbreak
        date: 2020-09-18
       words: 3210
      flesch: 32
     summary: The more precise and targeted detection of the virus can be carried out using biosensor based approaches. A pneumonia outbreak associated with a new coronavirus of probable bat origin Differential Sensitivities of Severe Acute Respiratory Syndrome (SARS)
    keywords: antibodies; biosensors; coronavirus; cov-2; covid-19; detection; diagnosis; patients; sars; surface
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        item: #1550 of 7819
          id: cord-268470-dgxn32ls
      author: Sharma, Abhishek
       title: Obesity is Associated with More Critical Illness in COVID-19
        date: 2020-07-02
       words: 934
      flesch: 49
     summary: key: cord-268470-dgxn32ls authors: Sharma, Abhishek; Garg, Akash; Rout, Amit; Lavie, Carl J. title: Obesity is Associated with More Critical Illness in COVID-19 date: 2020-07-02 journal: Mayo Clin Proc DOI: 10.1016/j.mayocp.2020.06.046 sha: doc_id: 268470 cord_uid: dgxn32ls nan To the Editor: In follow-up to recent major state-of-the-art review on Obesity and Outcomes in SARS-CoV-2 (COVID-19), 1 we have additional data regarding the relationship of obesity with outcomes in patients with COVID-19. When an Epidemic and Pandemic Collide Healthy Weight and Obesity Prevention: JACC Health Promotion Series Association of obesity with disease severity among patients with COVID-19 Obesity and COVID-19 Severity in a Designated Hospital in Shenzhen, China (3/13/2020) Lille Intensive Care COVID-19 and Obesity study group.
    keywords: covid-19; obesity; patients
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        item: #1551 of 7819
          id: cord-268483-joiajgs4
      author: Shah, Vibhuti Kumar
       title: Overview of Immune Response During SARS-CoV-2 Infection: Lessons From the Past
        date: 2020-08-07
       words: 10674
      flesch: 31
     summary: A randomized trial of hydroxychloroquine as postexposure prophylaxis for covid-19 Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-β1b (MIRACLE trial): study protocol for a randomized controlled trial Cinanserin is an inhibitor of the 3c-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro Inhibition of SARS-CoV 3CL protease by flavonoids Diarylheptanoids from Alnus japonica inhibit papain-like protease of severe acute respiratory syndrome coronavirus Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2 Feasibility of using convalescent plasma immunotherapy for MERS-CoV infection, Saudi Arabia Treatment with convalescent plasma for influenza A (H5N1) infection The convalescent sera option for containing COVID-19 Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 Effectiveness of convalescent plasma therapy in severe COVID-19 patients Use of convalescent plasma therapy in SARS patients in Hong Kong Available online at SARS vaccines: where are we? Neutralizing antibody against severe acute respiratory syndrome (SARS)-coronavirus spike is highly effective for the protection of mice in the murine SARS model SARS corona virus peptides recognized by antibodies in the sera of convalescent cases Severe acute respiratory syndrome (SARS) coronavirus: application of monoclonal antibodies and development of an effective vaccine Subunit vaccines against emerging pathogenic human coronaviruses Development of an inactivated vaccine candidate for SARS-CoV-2 ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus Effects of toll-like receptor stimulation on eosinophilic infiltration in lungs of BALB/c mice immunized with UV-inactivated severe acute respiratory syndrome-related coronavirus vaccine Neutralizing antibodies against SARS-CoV-2 and other human coronaviruses Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals A human monoclonal antibody blocking SARS-CoV-2 infection Identification of human single-domain antibodies against SARS-CoV-2 Microneedle array delivered recombinant coronavirus vaccines: immunogenicity and rapid translational development SARS-CoV-2 vaccines: status report Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies Mast cells contribute to coronavirus-induced inflammation: new anti-inflammatory strategy Clinical features of patients infected with 2019 novel coronavirus in Wuhan A phase 3, single-arm, prospective study of remestemcel-l, ex vivo culture-expanded adult human mesenchymal stromal cells for the treatment of pediatric patients who failed to respond to steroid treatment for acute graft-versus-host disease Remestemcel-L: Human mesenchymal stem cells as an emerging therapy for Crohn's disease Transplantation of ACE2-mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia (2020) Immune responses in COVID-19 and potential vaccines: lessons learned from SARS and MERS epidemic People Who Are at Higher Risk for Severe Illness | Coronavirus | COVID-19 Severe acute respiratory syndrome-associated coronavirus in lung tissue Multiple organ infection and the pathogenesis of SARS SARS-CoV-2 Infection in Children Vulnerability of children with COVID-19 infection and ACE2 profiles in lungs Possible causes for decreased susceptibility of children to coronavirus Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus Characteristics and outcomes of children with coronavirus disease 2019 (COVID-19) infection admitted to US and canadian pediatric intensive care units Outbreak of Kawasaki disease in children during COVID-19 pandemic: a prospective observational Features of COVID-19 post-infectious cytokine release syndrome in children presenting to the emergency department Links between innate and adaptive immunity via type I interferon Interferon and cytokine responses to SARScoronavirus infection SARS-CoV regulates immune function-related gene expression in human monocytic cells Profiles of antibody responses against severe acute respiratory syndrome coronavirus recombinant proteins and their potential use as diagnostic markers Early detection of antibodies against various structural proteins of the SARSassociated coronavirus in SARS patients Serological assays for emerging coronaviruses : challenges and pitfalls Profile of specific antibodies to the SARS-associated coronavirus T cell responses to whole SARS coronavirus in humans Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2 : an observational cohort study Profiling early humoral response to diagnose novel coronavirus disease (COVID-19) Viral kinetics and antibody responses in patients with COVID-19 Protective humoral immunity in SARS-CoV-2 infected pediatric patients The potential danger of suboptimal antibody responses in COVID-19 Medical countermeasures analysis of 2019-nCoV and vaccine risks for antibody-dependent enhancement (ADE) Antibody-dependent enhancement of SARS coronavirus infection and its role in the pathogenesis of SARS Molecular mechanism for antibody-dependent enhancement of coronavirus entry Avoiding pitfalls in the pursuit of a COVID-19 vaccine Novel immunodominant peptide presentation strategy: a featured HLA-A * 2402-restricted cytotoxic t-lymphocyte epitope stabilized by intrachain hydrogen bonds from severe acute respiratory syndrome coronavirus nucleocapsid protein Association of human leukocyte antigen class II alleles with severe acute respiratory syndrome in the Vietnamese population Epidemiological and genetic correlates of severe acute respiratory syndrome coronavirus infection in the hospital with the highest nosocomial infection rate in Taiwan in 2003 Humanleukocyte antigen class
    keywords: acute; antibodies; antibody; cells; coronavirus; cov-2; covid-19; host; human; immune; infection; mers; novel; patients; protein; response; sars; study; syndrome; treatment
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        item: #1552 of 7819
          id: cord-268524-lr51ubz5
      author: Droit-Volet, Sylvie
       title: Time and Covid-19 stress in the lockdown situation: Time free, «Dying» of boredom and sadness
        date: 2020-08-10
       words: 5272
      flesch: 49
     summary: A social-psychological investigation into the process of time orientation Mindfulness meditation, time judgment and time experience: Importance of the time scale considered (seconds or minutes) Awareness of the passage of time and self-consciousness: What do meditators report? Nonetheless, in the different distress scales used, the different dimensions of emotion (valence and arousal) were not dissociated, and no survey has examined their relationships to time experience, even though emotion and the experience of time are known to be intrinsically linked.
    keywords: boredom; covid-19; experience; lockdown; passage; stress; time
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        item: #1553 of 7819
          id: cord-268525-j06u3brl
      author: Lucchese, Guglielmo
       title: Cerebrospinal fluid findings in COVID-19 indicate autoimmunity
        date: 2020-10-07
       words: 286
      flesch: 34
     summary: Systematic SARS-CoV-2 screening in cerebrospinal fluid during the COVID-19 pandemic Cerebrospinal fluid findings in COVID-19 patients with neurological symptoms Cerebrospinal fluid features in SARS-CoV-2 RT-PCR positive patients Patients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid High frequency of cerebrospinal fluid autoantibodies in COVID-19 patients with neurological symptoms All of these studies showed that SARS-CoV-2 is not detectable in the CSF of patients with COVID-19 and neurological manifestations.
    keywords: patients
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        item: #1554 of 7819
          id: cord-268531-igjeai8c
      author: Zerah, Lorène
       title: Clinical Characteristics and Outcomes of 821 Older Patients With SARS-Cov-2 Infection Admitted to Acute Care Geriatric Wards: A Multicenter Retrospective Cohort Study
        date: 2020-08-26
       words: 4036
      flesch: 42
     summary: The mortality rate has been reported to be greater in patients with comorbidities, particularly diabetes, hypertension, obesity, and cardiovascular disease, and in older patients (5-10). Only 2 cohort studies of hospitalized patients, defined as geriatric, have been published but they included patients younger than 70 years and with few very old patients (11, 12) .
    keywords: characteristics; cohort; covid-19; disease; geriatric; hospital; mortality; patients; study
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        item: #1555 of 7819
          id: cord-268540-wrjzr3ws
      author: Park, You Jeong
       title: Fighting the War Against COVID-19 via Cell-Based Regenerative Medicine: Lessons Learned from 1918 Spanish Flu and Other Previous Pandemics
        date: 2020-08-13
       words: 16386
      flesch: 42
     summary: Clinical improvement following stem cell treatment will be assessed via frequency of adverse incidents, mortality rate, the number of ventilator and ICU free days, total hospital and ICU days, and improvement in oxygenation. The potent binding of SP to ACE2 and subsequent cellular infection may explain the prevalence of respiratory symptoms in COVID-19 patients.
    keywords: ace2; acute; cells; convalescent; coronavirus; cov-2; covid-19; covid-19 patients; disease; human; immune; infection; lung; mesenchymal; mscs; patients; plasma; sars; stem; stem cells; symptoms; syndrome; therapy; treatment; vaccine; virus
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        item: #1556 of 7819
          id: cord-268548-sujsnw2w
      author: Monaco, Maria Rita Lo
       title: An educational case series of Parkinson’s disease during the COVID-19 pandemic
        date: 2020-09-12
       words: 783
      flesch: 44
     summary: The authors declare no conflict of interest 1 Incidence of parkinsonism and Parkinson disease in a general population: the Rotterdam Study Mortality and causes of death in idiopathic Parkinson's disease: results from the Aberdeen whole population study Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the Finally, her family opted for comfort care, and she expired on hospital day 9. 56-year-old man with juvenile parkinsonism, presented to the Emergency Department with three days of dry cough, subjective fever, and myalgias.
    keywords: covid-19; disease; patients
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        item: #1557 of 7819
          id: cord-268561-vq1uhj5i
      author: da Silva, Severino Jefferson Ribeiro
       title: Clinical and Laboratory Diagnosis of SARS-CoV-2, the Virus Causing COVID-19
        date: 2020-08-04
       words: 9935
      flesch: 36
     summary: Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein Novel antibody epitopes dominate the antigenicity of spike glycoprotein in SARS-CoV-2 compared to SARS-CoV Protocol and Reagents for Pseudotyping Lentiviral Particles with SARS-CoV-2 Spike Protein for Neutralization Assays Cross-reactive Antibody Response between SARS-CoV-2 and SARS-CoV Infections Lack of cross-neutralization by SARS patient sera towards SARS-CoV-2 Analysis of the first cluster of cases in a family of novel coronavirus pneumonia in Gansu Province Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19) SARS-CoV-2 Seroconversion in Humans: A Detailed Protocol for a Serological Assay, Antigen Production, and Test Setup Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Test performance evaluation of SARS-CoV-2 serological assays Diagnostic performance of 7 rapid IgG/IgM antibody tests and the Euroimmun IgA/IgG ELISA in COVID-19 patients Development and Clinical Application of A Rapid IgM-IgG Combined Antibody Test for SARS-CoV-2 Infection Diagnosis Clinical Performance of Two SARS-CoV-2 Serologic Assays Serological immunochromatographic approach in diagnosis with SARS-CoV-2 infected COVID-19 patients Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibody Responses in Coronavirus Disease Clinical performance of different SARS-CoV-2 IgG antibody tests Evaluation of two automated and three rapid lateral flow immunoassays for the detection of anti-SARS-CoV-2 antibodies Establishment and validation of a pseudovirus neutralization assay for SARS-CoV-2 Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV Evaluation of novel antigen-based rapid detection test for the diagnosis of SARS-CoV-2 in respiratory samples Evaluation of rapid antigen test for detection of SARS-CoV-2 virus Development of a Portable, Ultra-Rapid and Ultra-Sensitive Cell-Based Biosensor for the Direct Detection of the SARS-CoV-2 S1 Microfluidic Immunoassays for Sensitive and Simultaneous Detection of IgG/IgM/Antigen of SARS-CoV-2 within 15 min 2020) In addition, several studies have been used to evaluate the clinical sensitivity of serological tests with COVID-19 patient samples collected on different days after the onset of symptoms.
    keywords: assays; cases; clinical; coronavirus; cov-2; covid-19; days; detection; diagnosis; disease; genome; infection; novel; patients; results; samples; sars; study; symptoms; tests
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        item: #1558 of 7819
          id: cord-268617-1t7yaoct
      author: Ismaili, Nabil
       title: COVID-19 and Gynecological Cancers: A Summary of International Recommendations
        date: 2020-08-31
       words: 3986
      flesch: 38
     summary: Cancer patients are more susceptible to develop an infection than people without cancer because of their immunosuppression caused by the disease and treatments (surgery and chemotherapy). Cancer patients are more susceptible to develop an infection than people without cancer because of their immunosuppression caused by the disease and treatments, such as chemotherapy and/or surgery.
    keywords: cancer; chemotherapy; covid-19; disease; patients; risk; stage; surgery; treatment
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        item: #1559 of 7819
          id: cord-268622-3jireyep
      author: Babadaei, Mohammad Mahdi Nejadi
       title: The expression level of angiotensin-converting enzyme 2 determines the severity of COVID-19: lung and heart tissue as targets
        date: 2020-06-01
       words: 4082
      flesch: 39
     summary: Figure 2C also shows the SARS-CoV-2 infection-related sensitive organs which can explain about the non-respiratory symptoms identified in COVID-19 patients . Pinto et al. (2020) also declared that ACE2 expression is enhanced in the lungs of COVID-19 patients with comorbidities.
    keywords: ace2; coronavirus; cov-2; covid-19; et al; infection; patients; sars
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        item: #1560 of 7819
          id: cord-268638-3lz60dyd
      author: Allen, Joshua C.
       title: Dispatches from the Frontlines: A Critical Care Nurse's Response to COVID19
        date: 2020-06-06
       words: 1494
      flesch: 53
     summary: By my next shift, we had exceeded SCDU critical care capacity and a nonbiocontainment ICU had been converted into COVID-19 critical care surge space. I needed to reconcile the arduous and often contradictory mandates of each endeavor: Biosafety requires slow, deliberate methodologies, while critical care often compels rapid, reflexive actions.
    keywords: care; covid-19; health; scdu
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        item: #1561 of 7819
          id: cord-268659-lhprkye6
      author: Hummel, James P.
       title: Temporal Trends in Arrhythmogenicity Related to Treatment of COVID-19 Infection
        date: 2020-09-15
       words: 1458
      flesch: 41
     summary: If excessive QTc prolongation was observed on telemetry recordings, it was always confirmed with a 12-lead ECG. Excessive QTc prolongation was defined as an increase in baseline QTc of ≥60 ms and absolute QTc >500 ms narrow QRS (or 550 ms wide QRS).
    keywords: hydroxychloroquine; patients; prolongation; qtc
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        item: #1562 of 7819
          id: cord-268662-mw8ec7u2
      author: Salton, Francesco
       title: Prolonged low-dose methylprednisolone in patients with severe COVID-19 pneumonia
        date: 2020-09-12
       words: 4410
      flesch: 40
     summary: No tracheostomy was necessary in MP patients vs. 12 controls (OR 0.04, 95% CI 0.002 to 0.64, p-value <0.001). [1] COVID-19 patients with ARF necessitate weeks of mechanical ventilation (MV) and have an unacceptably high mortality rate.
    keywords: covid-19; days; fio; icu; pao; patients; pneumonia; study; treatment
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        item: #1563 of 7819
          id: cord-268690-xle4bx49
      author: Gao, Lei
       title: Prognostic value of NT-proBNP in patients with severe COVID-19
        date: 2020-03-10
       words: 2012
      flesch: 47
     summary: The present study for the first time showed the relationship between plasma NT-proBNP level and risks of in-hospital death in severe COVID-19 patients. Severe COVID-19 patients with higher NT-proBNP levels tended to be older with higher levels of cardiac injury markers and higher levels of systematic inflammation markers.
    keywords: death; hospital; patients; probnp
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        item: #1564 of 7819
          id: cord-268693-td6kvmlq
      author: Martins, Leila Droprinchinski
       title: How socio-economic and atmospheric variables impact COVID-19 and Influenza outbreaks in tropical and subtropical regions of Brazil
        date: 2020-09-16
       words: 4437
      flesch: 40
     summary: The CFR values presented in Table 1 are higher when compared to statistics reported to other countries (Banerjee et al., 2020; Verity et al., 2020) . The fraction of elderly, one additional information captured by the HDI, is also an important risk factor, as already noticed and documented by Health Systems around the world (Banerjee et al., 2020; Yi-ru Wang, 2020; Verity et al., 2020) .
    keywords: climate; covid-19; et al; humidity; influenza; temperature; variables
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        item: #1565 of 7819
          id: cord-268705-crcs6d0a
      author: Harrogate, Suzanne
       title: Non-aneurysmal subarachnoid haemorrhage in COVID-19
        date: 2020-08-28
       words: 1247
      flesch: 36
     summary: A 74-year-old gentleman with confirmed COVID-19 and type 1 respiratory failure was admitted to the intensive care unit for mechanical ventilatory support. A 53-year-old gentleman with confirmed COVID-19 and type 1 respiratory failure required mechanical ventilatory support.
    keywords: covid-19; disease; sah
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        item: #1566 of 7819
          id: cord-268707-fip5e95c
      author: Williamson, Heather J
       title: Addressing the Needs of Rural Caregivers of Individuals With Alzheimer’s Disease and Related Dementias During and Beyond Coronavirus Disease 2019 (COVID-19)
        date: 2020-09-04
       words: 1445
      flesch: 42
     summary: Aging family caregivers of individuals with Alzheimer's disease and related dementias (ADRD) provide critical daily supports for their loved one. COVID-19 has shed light on the need to address social isolation among aging family caregivers, as it can have serious repercussions for health and quality of life (Holt-Lunstad, 2017) .
    keywords: aging; caregivers; covid-19; family; rural
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        item: #1567 of 7819
          id: cord-268716-lbxmteyn
      author: Erokhin, Vasilii
       title: Impacts of COVID-19 on Trade and Economic Aspects of Food Security: Evidence from 45 Developing Countries
        date: 2020-08-10
       words: 13015
      flesch: 49
     summary: The choice well correlates with the recommendations of Huseynov [53] , who used exchange rate, inflation rate, and food trade as variables to identify short-term and long-term effects on food security. From a mere health issue, the pandemic has turned into an economic threat to food security globally in the forms of lockdowns, economic decline, food trade restrictions, and rising food inflation.
    keywords: consumption; countries; covid-19; economies; food; food consumption; food security; food trade; group; health; income; inflation; number; pandemic; people; supply; trade; world
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        item: #1568 of 7819
          id: cord-268718-tt07cwrf
      author: Tan, Heng Wee
       title: Angiotensin‐converting enzyme 2: The old door for new severe acute respiratory syndrome coronavirus 2 infection
        date: 2020-06-30
       words: 6373
      flesch: 41
     summary: So far, three CoVs (HCoV-NL63, SARS-CoV, and SARS-CoV-2) have shown to utilize human ACE2 receptor. The known and suspected hosts of human coronaviruses that utilized human ACE2 receptors (HCoV-NL63, SARS-CoV, and SARS-CoV-2) are shown.
    keywords: ace2; coronavirus; cov; cov-2; covid-19; covs; enzyme; expression; host; human; patients; protein; receptor; sars; spike
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        item: #1569 of 7819
          id: cord-268721-n6dsc4ig
      author: Pawlowski, Colin
       title: Inference from longitudinal laboratory tests characterizes temporal evolution of COVID-19-associated coagulopathy (CAC)
        date: 2020-08-17
       words: 6970
      flesch: 32
     summary: However, the observations that DIC was formally diagnosed in only five of 2232 COVID pos patients and emphasizes that consumptive coagulopathy is an exception rather than the rule as it pertains to thrombotic phenotypes in COVID-19 patients. During each time window, we then compared the distribution of results from COVID pos versus COVID neg (matched) patients, allowing us to identify any lab tests which were significantly altered in COVID pos patients during any time of disease acquisition, onset, and/or progression.
    keywords: cohort; covid; covid pos; covid-19; days; lab; patients; pcr; pos; test; time
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        item: #1570 of 7819
          id: cord-268740-ldz5366v
      author: Sun, Mei
       title: Anal swab as the potentially optimal specimen for SARS-CoV-2 detection to evaluate the hospital discharge of COVID-19 patients
        date: 2020-08-14
       words: 2397
      flesch: 39
     summary: Coronavirus pathogenesis Genomic characterization and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): the epidemic and the challenges Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis High proportion of asymptomatic and presymptomatic COVID-19 infections in travelers and returning residents to Brunei Quadruple therapy for asymptomatic COVID-19 infection patients SARS-CoV-2 asymptomatic and symptomatic patients and risk for transfusion transmission National Health Commission of the People's Republic of China Detection and analysis of nucleic acid in various biological samples of COVID-19 patients Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes Positive RT-PCR Test Results in Patients Recovered From COVID-19 RT-PCR) test results in four health professionals discharged from hospitalization or quarantine after two negative RT-PCR test results and resolution of clinical COVID-19 infection Methodology for Sputum Induction and Laboratory Processing Potential preanalytical and analytical vulnerabilities in the laboratory diagnosis of coronavirus disease 2019 (COVID-19) Gemelli-pediatric COVID-19 team. Future microbiology DOI: 10.2217/fmb-2020-0090 sha: doc_id: 268740 cord_uid: ldz5366v Since December 2019, an outbreak of SARS coronavirus 2 (SARS-CoV-2) began in Wuhan, and has rapidly spread worldwide.
    keywords: cov-2; covid-19; detection; patients; sars; swabs
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        item: #1571 of 7819
          id: cord-268747-619eztla
      author: Bernar, Benoît
       title: SARS‐CoV‐2 infection in a 7‐year‐old girl with pancytopenia during acute lymphocytic leukemia maintenance therapy
        date: 2020-08-11
       words: 618
      flesch: 46
     summary: Our experience with this patient-so far as we know, the first child with COVID-19 during pancytopenia induced by maintenance therapy for ALL-suggests reassuringly that the course of COVID-19 in pediatric patients can be mild even if assessed risk for complications is high, as with immunosuppression and pancytopenia. In general, COVID-19 in children is rare, specifically in those aged <10 years, and its course appears milder than in adults.
    keywords: covid-19; patient; therapy
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        item: #1572 of 7819
          id: cord-268753-69d0l60v
      author: Pan, Zihan
       title: The role of CARDPC in response to COVID-19 in primary care in China
        date: 2020-09-18
       words: 2580
      flesch: 40
     summary: Strengthening the capability to manage COVID-19 and those most at risk in primary care has begun to build strength in primary care respiratory disease management, which is the foundation to improve the overall quality of prevention and control of respiratory diseases in the whole country. Thirdly, although primary health care is responsible for the management of common diseases, it must have the ability to deal with public health emergencies and make preparations in advance.
    keywords: cardpc; care; control; covid-19; diseases; prevention
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        item: #1573 of 7819
          id: cord-268758-2o2dwulc
      author: Daniel, Krupa
       title: Repeat cesarean section in a COVID-19 positive mother in the United States
        date: 2020-10-22
       words: 1414
      flesch: 50
     summary: As more people are infected, we encounter perinatal COVID-19 infections. In a review of the literature we have found evidence that may support the possibility of vertical transmission of COVID-19 infection.
    keywords: case; coronavirus; covid-19; infection; transmission
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        item: #1574 of 7819
          id: cord-268760-31i0mpvn
      author: Zhang, Qian
       title: Anosmia and Ageusia as the Only Indicators of Coronavirus Disease 2019 (COVID-19)
        date: 2020-05-01
       words: 2112
      flesch: 51
     summary: What are the symptoms of COVID-19 There's an unexpected loss of smell and taste in coronavirus patients Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study Anosmia and ageusia: common findings in COVID-19 patients Isolated sudden onset anosmia in COVID-19 infection. Symptoms of COVID-19 patients range widely from fever, respiratory symptoms, to newly reported findings of anosmia and ageusia from South Korea, Italy, and France.
    keywords: ageusia; anosmia; covid-19; patients; symptoms
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        item: #1575 of 7819
          id: cord-268761-yr0n5g7i
      author: Rao, Chalapati
       title: Medical certification of cause of death for COVID-19
        date: 2020-05-01
       words: 876
      flesch: 31
     summary: However, even the first basic mortality analysis from Italy during the first month of observations provides critical evidence on the higher proportions of males older than 70 years and of presence of multiple co-morbidities in COVID-19 deaths, although these were not specified in detail. 3 More importantly though, the Italian analysis discusses the key issue of defining COVID-19 deaths.
    keywords: covid-19; health; mortality
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        item: #1576 of 7819
          id: cord-268779-qbn3i2nq
      author: Alrasheed, Hend
       title: COVID-19 Spread in Saudi Arabia: Modeling, Simulation and Analysis
        date: 2020-10-23
       words: 10880
      flesch: 48
     summary: However, unlike other contact network generation models, we did not assume any network properties in advance [64, [70] Data Brief 2020, 105340 Modified SEIR and AI prediction of the epidemics trend of COVID-19 in China under public health interventions A conceptual model for the coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China with individual reaction and governmental action Estimation of the transmission risk of the 2019-nCoV and its implication for public health interventions Analysis and forecast of COVID-19 spreading in China, Italy and France Transmission dynamics of the COVID19 outbreak and effectiveness of government interventions: A data-driven analysis Interrupting COVID-19 transmission by implementing enhanced traffic control bundling: Implications for global prevention and control efforts Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts Modeling the epidemic dynamics and control of COVID-19 outbreak in China Effect of delay in diagnosis on transmission of COVID-19 Outbreak dynamics of COVID-19 in China and the United States Using the contact network model and Metropolis-Hastings sampling to reconstruct the COVID-19 spread on the Diamond Princess Impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand A contribution to the mathematical theory of epidemics Infectious Diseases of Humans: Dynamics and Control Complex Social Networks are Missing in the Dominant COVID-19 Epidemic Models Networks and epidemic models Networks and the epidemiology of infectious disease Epidemic spread in networks: Existing methods and current challenges Predicting the Epidemiological Outbreak of the Coronavirus Disease 2019 (COVID-19) in Saudi Arabia Epidemiological Modeling of COVID-19 in Saudi Arabia: Spread Projection, Awareness, and Impact of Treatment Dynamics of SARS-CoV-2 outbreak in the Kingdom of Saudi Arabia: A predictive model COVID-19 Outcomes in Saudi Arabia and the UK: A Tale of Two Kingdoms
    keywords: contact; control; covid-19; epidemic; measures; model; network; population; saudi; saudi arabia; social
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        item: #1577 of 7819
          id: cord-268809-plgip4h6
      author: Bielecki, Michel
       title: Social distancing alters the clinical course of COVID-19 in young adults: A comparative cohort study
        date: 2020-06-29
       words: 2610
      flesch: 46
     summary: A prospective contact-tracing study Exploration of the effectiveness of social distancing on respiratory pathogen transmission implicates environmental contributions Simulation suggests that rapid activation of social distancing can arrest epidemic development due to a novel strain of influenza Risk factors for SARS infection among hospital healthcare workers in Beijing: a case control study Handwashing and respiratory illness among young adults in military training1 1The full text of this article is available via AJPM Online at www.elsevier.com/locate/ajpmonline Physical interventions to interrupt or reduce the spread of respiratory viruses Assessing the airborne survival of bacteria in populations of aerosol droplets with a novel technology A new transmission route for the propagation of the SARS-CoV-2 coronavirus A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient Initial viral load and the outcomes of SARS Short term outcome and risk factors for adverse clinical outcomes in adults with severe acute respiratory syndrome (SARS) The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application Impact assessment of non-pharmaceutical interventions against coronavirus disease 2019 and influenza in Hong Kong: an observational study The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study Temporal dynamics in viral shedding and transmissibility of COVID-19 Follow-up of asymptomatic patients with SARS-CoV-2 infection Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship The contribution of asymptomatic SARS-CoV-2 infections to transmission-a model-based analysis of the Diamond Princess outbreak Asymptomatic and Presymptomatic SARS-CoV-2 Infections in Residents of a Long-Term Care Skilled Nursing Facility Asymptomatic cases in a family cluster with SARS-CoV-2 infection Herd immunity -estimating the level required to halt the COVID-19 epidemics in affected countries Repeated seroprevalence of anti-SARS-CoV-2 IgG antibodies in While both groups show evidence of infection, the rate of symptomatic COVID-19 amongst the infected soldiers differed significantly amongst the two groups and was much lower in the cohort where infection happened after the implementation of these measures.
    keywords: covid-19; p t
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        item: #1578 of 7819
          id: cord-268814-pk3gpumm
      author: Wasser, Lauren M.
       title: Response of ophthalmologists in Israel to the novel coronavirus (2019-nCoV) outbreak
        date: 2020-04-28
       words: 2342
      flesch: 43
     summary: COVID-19 guidelines were reportedly promulgated to hospital ophthalmologists but not to community and private physicians. A large number of practitioners described not being informed of official COVID-19 clinic guidelines, especially ophthalmologists practicing in busy outpatient clinics of health maintenance organizations (Kupat Holim).
    keywords: covid-19; israel; ophthalmologists; outbreak; practice; survey
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        item: #1579 of 7819
          id: cord-268816-nth3o6ot
      author: Roy, Satyaki
       title: Factors affecting COVID-19 infected and death rates inform lockdown-related policymaking
        date: 2020-10-23
       words: 5736
      flesch: 50
     summary: • Distance from one state to another (is not measured in miles but the euclidean distance between their latitude-longitude coordinates between the pair of states [32] ) (filename: source/Data_distance.xlsx, feature name: d(state1, state2)). • Gender feature(s) is a fraction of total population representing the male and female individuals [33] (filename: source/Data_gender.csv, feature name: Male, Female).
    keywords: age; airport; covid-19; death; factors; feature; infection; lockdown; population; pre; states; testing
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        item: #1580 of 7819
          id: cord-268817-wx96wwpg
      author: Karp, Donna Grace
       title: Sensitive and Specific Detection of SARS-CoV-2 Antibodies Using a High-Throughput, Fully Automated Liquid-Handling Robotic System
        date: 2020-08-20
       words: 3619
      flesch: 42
     summary: Here, we present an ultrasensitive and high-throughput automated liquid biopsy assay based on the Hamilton Microlab ADAP STAR automated liquid-handling platform, which was developed and validated for the qualitative detection of total antibodies against spike protein 1 (S1) of SARS-CoV-2 that uses as little as 4 µL of serum. The S1 protein is a high-quality antigen in that it shares less homology with other coronaviruses (~64% with S1 protein from SARS 2003), 11 whereas the nucleocapsid (N) protein shares extremely high homology (~91% with SARS 2003).
    keywords: adap; antibodies; antibody; assay; cov-2; covid-19; sars; specimens; total
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        item: #1581 of 7819
          id: cord-268822-o86zpu92
      author: Anser, Muhammad Khalid
       title: Communicable Diseases (Including COVID-19)—Induced Global Depression: Caused by Inadequate Healthcare Expenditures, Population Density, and Mass Panic
        date: 2020-08-18
       words: 5514
      flesch: 44
     summary: Thus, the impact of COVID-19 in the given study is negatively impacting countries' economic growth that converts into a global depression. Thus, the impact of COVID-19 in the given study is negatively impacting countries' economic growth that converts into a global depression.
    keywords: communicable; coronavirus; countries; covid-19; diseases; global; growth; healthcare; pandemic; population; study; world
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        item: #1582 of 7819
          id: cord-268827-qwcbvtna
      author: Ibanez, Agustin
       title: COVID-19 in older people with cognitive impairment in Latin America
        date: 2020-08-18
       words: 1469
      flesch: 45
     summary: The situation with professional health workers provides little solace. Other explanations point to economic inequality and inadequate public health systems 4 but fail to men tion the near absence of long-term care facilities and programmes for the cog ni tively impaired.
    keywords: covid-19; health; sars; synuclein
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        item: #1583 of 7819
          id: cord-268840-m3fp9q3p
      author: Sahu, Ankit Kumar
       title: Lung sonographic findings in COVID-19 patients
        date: 2020-09-04
       words: 2522
      flesch: 47
     summary: key: cord-268840-m3fp9q3p authors: Sahu, Ankit Kumar; Mathew, Roshan; Bhoi, Sanjeev; Sinha, Tej Prakash; Nayer, Jamshed; Aggarwal, Praveen title: Lung sonographic findings in COVID-19 patients date: 2020-09-04 journal: Am J Emerg Med DOI: 10.1016/j.ajem.2020.08.080 sha: doc_id: 268840 cord_uid: m3fp9q3p OBJECTIVE: The objective of this study was to describe the lung sonographic findings of COVID-19 patients prospectively and investigate its association with disease severity. This study was conducted in an emergency department and included consecutively enrolled laboratory confirmed COVID-19 patients.
    keywords: covid-19; disease; findings; lung; patients; ultrasound
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        item: #1584 of 7819
          id: cord-268874-ldja6aa4
      author: Park, Sun Hee
       title: Personal Protective Equipment for Healthcare Workers during the COVID-19 Pandemic
        date: 2020-06-24
       words: 6755
      flesch: 41
     summary: To protect HCWs against the splash/ spray of blood or bodily fluids as well as airborne particles (i.e., during an operation on a patient with COVID-19), surgical respirators with fluid resistance properties should be used [49] . Conventionally, respiratory transmission is classified as either droplet or airborne transmission
    keywords: covid-19; gowns; hcws; healthcare; masks; n95; ppe; protection; respirators; sars; transmission; use; virus
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        item: #1585 of 7819
          id: cord-268883-nf4fm7r7
      author: Corchuelo, Jairo
       title: Oral manifestations in a patient with a history of asymptomatic COVID-19. Case Report
        date: 2020-09-01
       words: 1681
      flesch: 35
     summary: Oral candida infection has been reported to almost always involve a locally or systemically compromised host (Zegarelli 1993) . Together, these agents explain the melanin pigmentation that is sometimes seen in association with inflammatory conditions of the skin or oral mucosa (Satomura et al. 2007 ).
    keywords: covid-19; patient
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        item: #1586 of 7819
          id: cord-268884-oi5l5f7f
      author: Shevlin, Mark
       title: Anxiety, depression, traumatic stress and COVID-19-related anxiety in the UK general population during the COVID-19 pandemic
        date: 2020-10-10
       words: 5769
      flesch: 45
     summary: Participants were asked to complete the ITQ '� in relation to UK population mental health and COVID-19 your experience of the COVID-19 pandemic. Higher levels of anxiety, depression and trauma symptoms were reported compared with previous population studies, but not dramatically so.
    keywords: anxiety; covid-19; depression; health; pandemic; participants; population; prevalence; study
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        item: #1587 of 7819
          id: cord-268897-vqbreyna
      author: Song, Young Goo
       title: COVID-19, A Clinical Syndrome Manifesting as Hypersensitivity Pneumonitis
        date: 2020-03-10
       words: 877
      flesch: 40
     summary: 3) Usually responded well to steroid treatment (personal communications) Radiology and pathology examinations of patients with COVID-19 revealed inflammatory reactions in the lung that resembled what is observed in hypersensitivity pneumonitis rather than in other viral pneumonia key: cord-268897-vqbreyna authors: Song, Young Goo; Shin, Hyoung-Shik title: COVID-19, A Clinical Syndrome Manifesting as Hypersensitivity Pneumonitis date: 2020-03-10 journal: Infect Chemother DOI: 10.3947/ic.2020.52.1.110 sha: doc_id: 268897 cord_uid: vqbreyna nan The coronavirus disease 2019 (COVID-19) which started in Wuhan, China, and affected most of the country, is spreading rapidly throughout the world in spite of the concerted efforts from the governments and World Health Organization (WHO) to contain it.
    keywords: covid-19; pneumonia
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        item: #1588 of 7819
          id: cord-268937-j2ov5nes
      author: Otuonye, N. M.
       title: CLINICAL AND DEMOGRAPHIC CHARACTERISTICS OF COVID-19 PATIENTS IN LAGOS, NIGERIA: A DESCRIPTIVE STUDY
        date: 2020-09-24
       words: 2920
      flesch: 50
     summary: This study was designed to provide a description of the clinical and demographic characteristics of COVID-19 patients in Nigeria. This study presents the most extensive description, to date, on the clinical and demographic characteristics of COVID-19 patients in Nigeria.
    keywords: covid-19; license; medrxiv; patients; preprint; study
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        item: #1589 of 7819
          id: cord-268939-ws74xprt
      author: Ozoner, Baris
       title: Neurosurgery Practice During Coronavirus Disease 2019 (COVID-19) Pandemic
        date: 2020-05-28
       words: 5145
      flesch: 41
     summary: Screening is crucial in all patients since the surgical outcome is highly mortal in COVID-19 patients. In this way, hub hospitals are available to manage neurosurgical emergencies, whereas spoke hospitals concentrate on COVID-19 patients.
    keywords: cases; china; coronavirus; cov-2; covid-19; disease; level; medical; neurosurgery; pandemic; patients; practice; sars
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        item: #1590 of 7819
          id: cord-268940-8th4ij8i
      author: Romito, Francesca
       title: Psychological Distress in Outpatients With Lymphoma During the COVID-19 Pandemic
        date: 2020-07-10
       words: 3727
      flesch: 39
     summary: In this perspective, there was an urgent need to draw up specific recommendations in order to protect cancer patients and, at the same time, to guarantee continuation of care. Even if the epidemiological data on the incidence of COVID-19 infection in cancer patients and its rate of morbidity and mortality in Italy had not yet been published, since the beginning of March, the Società Italiana di Ematologia (SIE), the Gruppo Italiano Trapianti di Midollo Osseo (GITMO), Fondazione Italiana Linfomi (FIL), and the Associazione Italiana di Oncologia Medica (AIOM) disclosed recommendations on the management of onco-hematologic patients 3, 4, 5 . Lymphoproliferative neoplasms, including non-Hodgkin's lymphomas (NHL), classical Hodgkin lymphoma (cHL), and Chronic lymphocytic leukemia/Small lymphocytic lymphoma (CLL/SLL), because of better diagnostic tools and targeted therapies, now show a cumulative cure rate of about 70%; one of their main complications, however, is that of opportunistic infections due to the intrinsic and iatrogenic suppression of the immune system (9, 10) .
    keywords: anxiety; cancer; covid-19; depression; hads; pandemic; patients
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        item: #1591 of 7819
          id: cord-268948-1ns6zi27
      author: Shi, Yaling
       title: Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou, China
        date: 2020-03-16
       words: 3167
      flesch: 54
     summary: The immunopathological characteristics of COVID-19 patients, either systemic or local, have not been thoroughly studied. The immune response in COVID-19 patients, either systemic or local, has not been well studied even one month after the COVID-19 outbreak in China.
    keywords: cells; covid-19; license; medrxiv; patients; preprint
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        item: #1592 of 7819
          id: cord-268952-3j43p9j3
      author: Ueda Oshima, Masumi
       title: Blood and marrow transplantation during the emerging COVID-19 pandemic: the Seattle approach
        date: 2020-09-26
       words: 3646
      flesch: 34
     summary: Finally, as the Seattle Children's Hospital had a significantly lower caseload of COVID-19 patients compared to the adult medicine services at UW, any willing adolescent and young adult patient in need of urgent transplantation was transferred to receive care by our pediatric BMT colleagues. Situated in the initial epicenter of the pandemic, the Blood and Marrow Transplant (BMT) Program at Fred Hutchinson Cancer Research Center (Fred Hutch)/Seattle Cancer Care Alliance (SCCA) was at the forefront of delivering care to transplant patients during the surge of this public health crisis.
    keywords: care; cell; clinical; covid-19; pandemic; patients; program; staff; transplant; transplantation
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        item: #1593 of 7819
          id: cord-269009-0i2bvt77
      author: D’Souza, Rohan
       title: A critical review of the pathophysiology of thrombotic complications and clinical practice recommendations for thromboprophylaxis in pregnant patients with COVID‐19
        date: 2020-08-05
       words: 3302
      flesch: 28
     summary: The origin of the very elevated D-dimer levels in COVID-19 patients may at least in part be the pneumocytes, which can produce urokinase. COVID-19 patients have a higher thromboembolic risk, which is further increased by the pregnancy and postpartum situation.
    keywords: coagulation; covid-19; patients; pregnancy; pulmonary; risk; thromboprophylaxis; vte; women
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        item: #1594 of 7819
          id: cord-269031-sz8ieltb
      author: Solé, G
       title: Guidance for the care of neuromuscular patients during the COVID-19 pandemic outbreak from the French Rare Health Care for Neuromuscular Diseases Network
        date: 2020-04-20
       words: 5750
      flesch: 33
     summary: key: cord-269031-sz8ieltb authors: Solé, G; Salort-Campana, E; Pereon, Y; Stojkovic, T; Wahbi, K; Cintas, P; Adams, D; Laforet, P; Tiffreau, V; Desguerre, I; Pisella, LI; Molon, A; Attarian, S title: Guidance for the care of neuromuscular patients during the COVID-19 pandemic outbreak from the French Rare Health Care for Neuromuscular Diseases Network date: 2020-04-20 journal: Rev Neurol (Paris) DOI: 10.1016/j.neurol.2020.04.004 sha: doc_id: 269031 cord_uid: sz8ieltb Abstract In France, the epidemic phase of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in February 2020 and resulted in the implementation of emergency measures and a degradation in the organization of neuromuscular reference centers. The French Rare Health Care for Neuromuscular Diseases Network (FILNEMUS) also announced guidance in an attempt to homogenize the management of neuromuscular patients in this context to limit the contamination of extremely fragile patients while avoiding the loss of survival chance linked to the interruption of essential treatment or follow-up.
    keywords: care; context; covid-19; diseases; emergency; gravis; health; months; myasthenia; patients; risk; therapy; treatment
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        item: #1595 of 7819
          id: cord-269044-47dmpmo0
      author: Fantola, Giovanni
       title: Is There a Role for ERAS Program Implementation to Restart Bariatric Surgery After the Peak of COVID-19 Pandemic?
        date: 2020-05-15
       words: 1090
      flesch: 43
     summary: Society Statement COVID-19: recommendations for management of elective surgical procedures SAGES and EAES recommendations regarding surgical response to Covid-19 crisis Importance of metabolic health in the era of COVID-19 Obesity and impaired metabolic health in patients with COVID-19 High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation Obesity is associated with severe forms of COVID-19 Recommendations for metabolic and bariatric surgery during the COVID-19 pandemic from IFSO Bariatric surgery versus intensive medical therapy for diabetes -5-year outcomes IFSO worldwide survey 2016: primary, endoluminal, and revisional procedures Practical recommendations of the obesity management task force of the European Association for the Study of obesity for the post-bariatric surgery medical management Obesity hypoventilation syndrome and severe COVID-19 Obesity and its implications for COVID-19 mortality Enhanced recovery after bariatric surgery: 202 consecutive patients in an Italian bariatric center Enhanced recovery after bariatric surgery (ERABS) in a high-volume bariatric center Enhanced recovery after bariatric surgery: systematic review and meta-analysis Results of implementing an enhanced recovery after bariatric surgery (ERABS) protocol Value-based healthcare and enhanced recovery after surgery implementation in a high-volume bariatric center in Italy Perioperative care of the obese patient Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Acknowledgments In Italy, accordingly to other affected countries, bariatric surgery (BS) was promptly and diffusely stopped.
    keywords: covid-19; obesity; surgery
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        item: #1596 of 7819
          id: cord-269077-gz7jxidl
      author: Hamidi, Shima
       title: Compact development and adherence to stay-at-home order during the COVID-19 pandemic: A longitudinal investigation in the United States
        date: 2020-09-30
       words: 7481
      flesch: 39
     summary: Google COVID-19 community mobility reports: Anonymization process description (version 1.0) Polarization and public health: Partisan differences in social distancing during the coronavirus pandemic Pandemic influenza in Australia: Using telephone surveys to measure perceptions of threat and willingness to comply Risk perception through the lens of politics in the time of the covid-19 pandemic Civic capital and social distancing during the covid-19 pandemic (No. w27320) Listen to the people: Public deliberation about social distancing measures in a pandemic Demographic and attitudinal determinants of protective behaviors during a pandemic: A review Does partisanship shape attitudes toward science and public policy? key: cord-269077-gz7jxidl authors: Hamidi, Shima; Zandiatashbar, Ahoura title: Compact development and adherence to stay-at-home order during the COVID-19 pandemic: A longitudinal investigation in the United States date: 2020-09-30 journal: Landsc Urban Plan DOI: 10.1016/j.landurbplan.2020.103952 sha: doc_id: 269077 cord_uid: gz7jxidl In the absence of a vaccine and medical treatments, social distancing remains the only option available to governments in order to slow the spread of global pandemics such as COVID-19 and save millions of lives.
    keywords: areas; counties; county; covid-19; distancing; grocery; order; pandemic; parks; place; place order; reduction; shelter; transit; travel; trips
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        item: #1597 of 7819
          id: cord-269083-8mjdb9yj
      author: Muhović, Damir
       title: First case of drug‐induced liver injury associated with the use of tocilizumab in a patient with COVID‐19
        date: 2020-06-01
       words: 1448
      flesch: 41
     summary: We describe a patient with COVID‐19‐induced cytokine storm who developed drug‐induced liver injury associated with the use of TCZ. 16 Most patients with severe COVID-19 have a history of simultaneous use of multiple drugs that can induce liver injury.
    keywords: covid-19; il-6; injury; liver; tcz
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        item: #1598 of 7819
          id: cord-269087-f9hyntvf
      author: Li, X.
       title: A Mini Review on Current Clinical and Research Findings for Children Suffering from COVID-19
        date: 2020-04-04
       words: 4282
      flesch: 45
     summary: Yet, in more general, infectious diseases often tend to behave less aggressively in child patients. A single child patient passed away; for other child patients, progression of the disease was observed as mild [9, 10] .
    keywords: cases; children; coronavirus; cov-2; covid-19; diagnosis; infection; patients; sars
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        item: #1599 of 7819
          id: cord-269090-o93gxlzx
      author: Sciortino, Rosalia
       title: Towards A Comprehensive Narrative and Response to COVID-19 in Southeast Asia
        date: 2020-09-01
       words: 4117
      flesch: 38
     summary: Based on our disciplinary core principles and what has been learned from other epidemics, foremost HIV, we can help shift a purely epidemiological approach to addressing the social drivers of vulnerability and risk for diverse populations in specific social contexts, and build agency of these groups while promoting social transformative change. In explaining differences in prevalence, incidence and fatality rates within and across countries, we should be weary of simplistic discussions and engage on social media to encourage the public to be statistically literate i.e. to think critically about the information being presented; to understand the context; and to be able to tell the story in the data [15] .
    keywords: asia; covid-19; health; human; measures; pandemic; people; risk; socio; southeast
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        item: #1600 of 7819
          id: cord-269101-7altkx5u
      author: Jakhmola Mani, Ruchi
       title: Deciphering underlying mechanism of Sars-CoV-2 infection in humans and revealing the therapeutic potential of bioactive constituents from Nigella sativa to combat COVID19: in-silico study
        date: 2020-10-28
       words: 4941
      flesch: 42
     summary: Since ACE2 is a target site for SARS-CoV-2 therefore a network was generated around this protein to depict a disease network and N. sativa constituents was used as a treatment network. On the other end, N. sativa constituents collectively were also targeting these as well other families such as Nuclear receptors, Cytochrome P450, Oxidoreductases, Erasers, Lyases, Enzymes, Family A G protein coupled receptors, calcium signaling pathways, Circadian pathways, Foxo pathway etc.
    keywords: ace2; constituents; cov-2; covid-19; network; protein; receptor; sars; sativa; study
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        item: #1601 of 7819
          id: cord-269105-yuphgyrn
      author: Dumantepe, Mert
       title: Subsegmental Thrombus in COVID-19 Pneumonia: Immunothrombosis or Pulmonary Embolism? Data Analysis of Hospitalised Patients With Coronavirus Disease
        date: 2020-08-24
       words: 1328
      flesch: 32
     summary: A novel coronavirus from patients with pneumonia in China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Incidence of venous thromboembolism in hospitalized patients with COVID-19 Clinical management of severe acute respiratory infection (SARI) when novel coronavirus (2019-nCoV) infection is suspected (Interim guidance Version 1.2) Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past SARS-CoV-2 and viral sepsis: observations and hypotheses The stimulation of thrombosis by hypoxia Autopsy findings and venous thromboembolism in patients with COVID-19: a prospective cohort study Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Acute pulmonary embolism associated with COVID-19 pneumonia detected by pulmonary CT angiography Catheter directed ultrasound-accelerated thrombolysis for the treatment of acute pulmonary embolism Improvements in pulmonary artery pressure and right ventricular function after ultrasound-accelerated catheter-directed thrombolysis for the treatment of pulmonary embolism Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. The current results showed frequent VTE in patients with COVID-19 infection.
    keywords: coronavirus; covid-19; patients; pulmonary
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        item: #1602 of 7819
          id: cord-269130-zsem29ss
      author: Lingappan, K.
       title: Understanding the age divide in COVID-19: why are children overwhelmingly spared?
        date: 2020-07-01
       words: 3124
      flesch: 34
     summary: Adult murine lungs had significantly lower IL-10 and IL-13 levels before infection than young murine lungs and produced high levels of proinflammatory mediators leading to macrophage and neutrophil infiltration and activation (25) . On the other hand, the heightened immune response to the virus in many adult patients can lead to the worsening of lung disease with SARS-CoV-2 infection (37) .
    keywords: adults; children; coronavirus; covid-19; disease; infection; lung; sars
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        item: #1603 of 7819
          id: cord-269164-jdgzx1ss
      author: Machluf, Yossy
       title: Gender medicine: Lessons from COVID-19 and other medical conditions for designing health policy
        date: 2020-09-06
       words: 8805
      flesch: 37
     summary: A conduit between epidemiological research and regional health policy Barriers and facilitators for the development of sex/gender sensitive clinical practice guidelines: A qualitative interview study Embedding concepts of sex and gender health differences into medical curricula Emergency Medicine Gender-specific Education Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice: A Brief Narrative Review Implementation Strategies for Gender-Sensitive Public Health Practice: A European Workshop Darmstadt GL; Gender Equality, Norms and Health Steering Committee. Gender differences may also develop and change over time, as they are age-related.
    keywords: asthma; ckd; clinical; conditions; covid-19; data; differences; disease; gender; gender differences; guidelines; health; medical; risk; treatment; women
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        item: #1604 of 7819
          id: cord-269197-o9xb30vx
      author: Osserman, Jordan
       title: Waiting for other people: a psychoanalytic interpretation of the time for action
        date: 2020-06-10
       words: 4172
      flesch: 52
     summary: Yet, these investors do not decide whether to buy or sell stocks based directly on what they think other investors will do, but through the mechanism of a presupposed, transubjective third: what I think other people think 'the market' is going to do (see Tuckett, 2011). key: cord-269197-o9xb30vx authors: Osserman, Jordan; Lê, Aimée title: Waiting for other people: a psychoanalytic interpretation of the time for action date: 2020-06-10 journal: Wellcome Open Res DOI: 10.12688/wellcomeopenres.15959.1 sha: doc_id: 269197 cord_uid: o9xb30vx Typical responses to a confrontation with failures in authority, or what Lacanians term ‘the lack in the Other’, involve attempts to shore it up.
    keywords: act; covid-19; crisis; government; lack; nhs; people; time; work
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        item: #1605 of 7819
          id: cord-269202-re2djjrc
      author: Sapino, Anna
       title: The autopsy debate during the COVID-19 emergency: the Italian experience
        date: 2020-04-29
       words: 1142
      flesch: 40
     summary: We acknowledged that safety of operators must be the main goal to confront with, and we defined the criteria to perform the post-mortem studies in suspect, probable, or confirmed COVID-19 cases Apart from suspect, probable, or confirmed COVID-19 cases, autopsies might be requested for patients not suspected to be SARS-Cov2 positive.
    keywords: autopsy; cases; covid-19; sars
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        item: #1606 of 7819
          id: cord-269206-160ddfsc
      author: Ceylan, Rahmiye Figen
       title: Historical evidence for economic effects of COVID-19
        date: 2020-06-04
       words: 4555
      flesch: 49
     summary: key: cord-269206-160ddfsc authors: Ceylan, Rahmiye Figen; Ozkan, Burhan; Mulazimogullari, Esra title: Historical evidence for economic effects of COVID-19 date: 2020-06-04 journal: Thus, discussing economic effects of previous global and regional epidemics is considered beneficial.
    keywords: consumption; covid-19; demand; effects; flu; impact; income; labour; loss; services
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        item: #1607 of 7819
          id: cord-269241-6mf5572t
      author: López-Feldman, Alejandro
       title: Environmental Impacts and Policy Responses to Covid-19: A View from Latin America
        date: 2020-07-13
       words: 2472
      flesch: 43
     summary: We discuss potential effects on environmental regulations, possible policy interventions, and an agenda for future research for those interested in the design and evaluation of environmental policies relevant for the Latin American context. The economic crisis can end up having long-run negative consequences for the environment if, as a result, regulations and environmental policies are relaxed or if institutions are weakened.
    keywords: america; countries; covid-19; effects; latin; pandemic; region; run
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        item: #1608 of 7819
          id: cord-269245-bp4q4plt
      author: Zhang, Yuan
       title: Status and influential factors of anxiety depression and insomnia symptoms in the work resumption period of COVID-19 epidemic: A multicenter cross-sectional study
        date: 2020-09-18
       words: 2844
      flesch: 38
     summary: However, more attention In the present study, only 17.4% of current participants had received psychological interventions, 5.2% had received individual psychological interventions during the outbreak of COVID-19. During the epidemic, 17.4% of the participants had received psychological interventions, and only 5.2% had received individual interventions.
    keywords: anxiety; covid-19; depression; insomnia; interventions; study; symptoms
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        item: #1609 of 7819
          id: cord-269275-b7xxk48t
      author: Tang, Xiaojia
       title: Neurological manifestations in COVID-19 and its possible mechanism
        date: 2020-09-27
       words: 4640
      flesch: 39
     summary: Four formal reports have described neurological problems in SARS patients, including polyneuropathy The symptoms of hypoxia in COVID-19 patients are very obvious, and critical patients need ventilator support.
    keywords: acute; cells; coronavirus; cov-2; covid-19; human; infection; novel; patients; rhabdomyolysis; sars; syndrome; system
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        item: #1610 of 7819
          id: cord-269280-1zbxjmxu
      author: Shao, Connie
       title: The COVID trolley dilemma
        date: 2020-05-14
       words: 2902
      flesch: 54
     summary: At a time when hospitals are furloughing staff, reducing salaries for staff, and scrambling for PPE for their employees, it would be in the financial interest of keeping a hospital running to proceed with elective surgeries in an effort to help mend the expected deficits of hundreds of millions per hospital. As certain areas in the country have the resources to resume elective surgery, how will they be remembered in a time when other, heavily affected parts of the country struggle with unmet needs for goods and services?
    keywords: covid-19; elective; hospital; number; pandemic; patients; trolley
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        item: #1611 of 7819
          id: cord-269283-jm18lj5t
      author: Uddin, Md Bashir
       title: Ancestral origin, antigenic resemblance and epidemiological insights of novel coronavirus (SARS-CoV-2): Global burden and Bangladesh perspective
        date: 2020-07-01
       words: 2746
      flesch: 43
     summary: Immunogenicity and epitope conservancy analyses of coronavirus proteins were performed to determine the potential B-cell epitopes that would interact efficiently with B lymphocytes to initiate the immune response against specific viral pathogens The cross-checked conservancy analysis of SARS-CoV-2 antigenic epitopes showed significant conservancy with antigenic epitopes derived from SARS-CoV.
    keywords: coronavirus; cov-2; covid-19; novel; proteins; sars
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        item: #1612 of 7819
          id: cord-269301-3e5uxunm
      author: Yilmaz, Resul
       title: Anesthetic management for cesarean birth in pregnancy with the novel coronavirus (COVID-19)
        date: 2020-05-27
       words: 714
      flesch: 55
     summary: [3] , spinal anesthesia was performed and it was reported to be completed safely. Based on these two reports, we preferred to apply spinal anesthesia.
    keywords: anesthesia
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        item: #1613 of 7819
          id: cord-269316-1nlpo42a
      author: Mansfield, K. E.
       title: COVID-19 collateral: Indirect acute effects of the pandemic on physical and mental health in the UK
        date: 2020-10-30
       words: 8037
      flesch: 42
     summary: [60] However, we saw a sustained reduction in primary care contacts for anxiety, depression and other mental health conditions consistent with other reports; 18 this is concerning as the majority of common mental disorders are managed in primary care. Primary care contacts for all conditions dropped dramatically after introduction of population-wide restrictions.
    keywords: acute; care; contacts; covid-19; health; j u; population; preprint; study
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        item: #1614 of 7819
          id: cord-269328-ypjc5v60
      author: Kamran, Aziz
       title: The COVID-19 outbreak and behavioral changes, public perceptions and psychological responses in Iran
        date: 2020-08-07
       words: 210
      flesch: 25
     summary: Commentary: Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group Identification of a new human coronavirus The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak Effective recommendations for reducing anxiety and depression caused by COVID-19 outbreak in medical staff Research on COVID-19 Virus Spreading Statistics based on the Examples of the Cases from Different Countries A Mathematical Modelling Approach in the Spread of the Novel 2019 Coronavirus SARS-CoV-2 (COVID-19) Pandemic Coronavirus disease (COVID-19) outbreak provides a unique platform to review behavioral changes in Iran. key: cord-269328-ypjc5v60 authors: Kamran, Aziz; Naeim, Mahdi; Rezaeisharif, Ali title: The COVID-19 outbreak and behavioral changes, public perceptions and psychological responses in Iran date: 2020-08-07 journal: Arch Psychiatr Nurs DOI: 10.1016/j.apnu.2020.08.002 sha: doc_id: 269328 cord_uid: ypjc5v60 nan involvement in controlling the spread of the disease has been unprecedented, such as locking up Qom and surrounding towns, extending holidays and closing schools, sending thousands of medical personnel to the affected areas, and launching intense public messaging campaigns.
    keywords: covid-19
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        item: #1615 of 7819
          id: cord-269344-7ik9e5m4
      author: Gerussi, Alessio
       title: Coronavirus Disease 2019 (COVID‐19) in autoimmune hepatitis: a lesson from immunosuppressed patients
        date: 2020-06-09
       words: 1928
      flesch: 40
     summary: Our study is a case series of AIH patients treated with immunosuppression, who tested positive for SARS‐CoV‐2 in March 2020 during outbreak of COVID‐19. All rights reserved The main limitations of this study are the small sample size and the short follow-up, that prevent us to infer whether treated AIH patients have a specific clinical phenotype: to answer this research question we would have need a larger sample size and longer observation.
    keywords: aih; covid-19; immunosuppression; patients
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        item: #1616 of 7819
          id: cord-269347-oc2pb00b
      author: Ahmad, I.
       title: Guillain Barr e syndrome in COVID-19:A scoping review
        date: 2020-06-16
       words: 4683
      flesch: 51
     summary: This paraparetic pattern is seen more commonly in Zika Virus associated GBS cases. In addition, mortality in COVID-19 cases due to rapidly progressive respiratory failure is usually attributed to the COVID-19 itself.
    keywords: cases; covid-19; funder; gbs; medrxiv; preprint; review; syndrome
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        item: #1617 of 7819
          id: cord-269408-6qncy0nd
      author: Khonyongwa, Kirstin
       title: Incidence and outcomes of healthcare-associated COVID-19 infections: significance of delayed diagnosis and correlation with staff absence
        date: 2020-10-13
       words: 4132
      flesch: 48
     summary: Early diagnosis and isolation of COVID-19 patients would help reduce transmission. Cohort areas were segregated by at least a passageway and the beds allocated to COVID-19 patients clearly signposted as the cohort area.
    keywords: cases; covid-19; hospital; incidence; patients; rna; sars; staff; study
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        item: #1618 of 7819
          id: cord-269417-dtu7711x
      author: Hirashima, Tomonori
       title: Factors significantly associated with COVID-19 severity in symptomatic patients: A retrospective single-center study
        date: 2020-10-10
       words: 4084
      flesch: 45
     summary: Thus, GCT can have beneficial effects in COVID-19 patients with ARDS. However, a recent study [33] showed that high dose methylprednisolone followed by tocilizumab improved the clinical status of COVID-19 patients with cytokine storm syndrome.
    keywords: covid-19; csi; data; illness; japanese; mmi; patients; severity; study; tocilizumab
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        item: #1619 of 7819
          id: cord-269425-e9iyso7n
      author: Bhattacharjee, Sukrita
       title: Immune Thrombocytopenia Secondary to COVID-19: a Systematic Review
        date: 2020-09-19
       words: 5429
      flesch: 43
     summary: A systematic review was done to analyze the clinical profile and outcomes in a total of 45 cases of new-onset ITP in COVID-19 patients described in literature until date. Clinicians should also take note of several reports of ITP in COVID-19 patients in post-recovery period (21%).
    keywords: bleeding; cases; covid-19; immune; itp; onset; patients; platelet; response; review; thrombocytopenia
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        item: #1620 of 7819
          id: cord-269428-0cusg8d1
      author: Sari, Dina Keumala
       title: Positive Correlation Between General Public Knowledge and Attitudes Regarding COVID-19 Outbreak 1 Month After First Cases Reported in Indonesia
        date: 2020-06-24
       words: 4135
      flesch: 49
     summary: Cases of COVID-19 infection have spread throughout the world. The consequences of this are economic hardship, which forces people to leave their house to work, and ignorance regarding the dangers of COVID-19 infection.
    keywords: attitudes; covid-19; indonesia; knowledge; public; respondents; study
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        item: #1621 of 7819
          id: cord-269440-6x19xuy3
      author: Seo, Min Young
       title: Trend of Olfactory and Gustatory Dysfunction in COVID-19 Patients in a Quarantine Facility
        date: 2020-10-20
       words: 2680
      flesch: 40
     summary: The relationship between phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) taster status and taste thresholds for sucrose and quinine Comparison of bitterness of caffeine and quinine by a time-intensity procedure Sweetness of sucrose, neohesperidin dihydrochalcone, and saccharin is related to genetic ability to taste the bitter substance 6-n-propylthiouracil Prevalence and duration of acute loss of smell or taste in COVID-19 patients Clinical diagnosis and current management strategies for olfactory dysfunction: a review Identification of viruses in patients with postviral olfactory dysfunction Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neurotropic mechanisms Chemotherapy-induced nausea and vomiting: incidence and impact on patient quality of life at community oncology settings PTC taste blindness and the taste of caffeine Detection thresholds for quinine, PTC, and PROP measured using taste strips In conclusion, the prevalence of olfactory dysfunction was 24.2% in mild COVID-19 patients and all patients had hyposmia due to sensorineural olfactory dysfunction, which was confirmed using validated olfactory and gustatory evaluation methods and endoscopic examination. 6-11 In a study by Moein et al., 12 the University of Pennsylvania Smell Identification Test (UPSIT) was used in the assessment of smell dysfunction, and olfactory and gustatory dysfunction were identified in 90% (59/60) and 25% (15/60) of COVID-19 patients, respectively.
    keywords: covid-19; dysfunction; gustatory; olfactory; patients; study
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        item: #1622 of 7819
          id: cord-269445-dctx9c7w
      author: Razanamahery, J.
       title: Predictive factors of poor outcomes in the COVID-19 epidemic: Consider the inflammatory response
        date: 2020-04-24
       words: 1054
      flesch: 52
     summary: We aimed to identify risks factors for poor outcome of COVID-19 infection in hospitalized patients during the first month of the pandemic in Besanç on University Hospital. High levels of CRP, PCT, AST, and LDH were associated with poor outcome (Table 1) .
    keywords: covid-19; crp; levels; patients
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        item: #1623 of 7819
          id: cord-269453-30l6rzgo
      author: Yang, Po
       title: Feasibility study of mitigation and suppression strategies for controlling COVID-19 outbreaks in London and Wuhan
        date: 2020-08-06
       words: 6785
      flesch: 49
     summary: Suppression intervention from the 32 nd day: the peak of daily infections greatly reduced to 16 thousand, but it had to be followed at least 200 days. We used a benchmark reported in [11] that assumes Hubei province with no intervention as M = 15, and after suppression intervention, M reduced to 3.
    keywords: cases; covid-19; intervention; london; model; number; population; suppression; wuhan
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        item: #1624 of 7819
          id: cord-269469-7pmnxi9a
      author: Bikdeli, Behnood
       title: Anticoagulation in COVID-19: Randomized trials should set the balance between excitement and evidence
        date: 2020-10-08
       words: 1060
      flesch: 35
     summary: A Single Health System Study D-dimer cut-off points and risk of venous thromboembolism in adult hospitalized patients with COVID-19 Scientific and Standardization Committee communication: Clinical guidance on the diagnosis, prevention, and treatment of venous thromboembolism in hospitalized patients with COVID-19 Prevention, Diagnosis, and Treatment of VTE in Patients With Coronavirus Disease Intermediate versus Standard-dose Prophylactic anticoagulation and Statin Therapy versus Placebo in Critically-ill Patients with COVID-19: Rationale and Design of the INSPIRATION/ INSPIRATION-S Studies Anticoagulant interventions in hospitalized patients with COVID-19: COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis High Prevalence of Deep Vein Thrombosis in Mechanically Ventilated COVID-19 Patients High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Association of Treatment Dose Anticoagulation With In-Hospital Survival Among Hospitalized Patients With COVID-19 Anticoagulation, Mortality, Bleeding and Pathology Among Patients Hospitalized with COVID-19:
    keywords: covid-19; patients; study
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        item: #1625 of 7819
          id: cord-269484-jjbctg96
      author: Piraux, Arthur
       title: Covigie, une plateforme pour les soignants et les coordonnateurs d’équipes de soins
        date: 2020-10-20
       words: 2078
      flesch: 54
     summary: Des pistes sont déjà en cours d'exploration, comme l'extension au champ de la qualité et de l'organisation des soins, un outil de mise en commun et de signalement orienté sur les communautés professionnelles territoriales de santé et un outil d'enquête à l'initiative des promoteurs, des parte naires ou des autorités. F Covigie a donc constitué un véritable relais de l'infor mation, fonctionnant à la fois de manière ascendante et descendante.
    keywords: covid-19; covigie; des; les; ont; par; pour; été
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        item: #1626 of 7819
          id: cord-269503-ij4u980v
      author: Amaratunga, Eluwana A
       title: Bradycardia in Patients With COVID-19: A Calm Before the Storm?
        date: 2020-06-13
       words: 3497
      flesch: 41
     summary: As previously described, acute myocardial injury was thought to be the most common cardiac manifestation in COVID-19 patients and potential for developing cardiac arrhythmias has been noted in a few studies. The etiology of cardiac manifestations in COVID-19 patients seems to be multifactorial, which includes direct viral myocardial damage, hypoxia, hypotension, enhanced inflammatory status, angiotensin-converting enzyme 2 (ACE2)-receptor downregulation, drug toxicity, and endogenous catecholamine adrenergic status [5, 7] .
    keywords: admission; bradycardia; covid-19; day; days; onset; patients
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        item: #1627 of 7819
          id: cord-269511-bfd1dmt3
      author: Salacup, Grace
       title: Characteristics and Clinical Outcomes of COVID‐19 Patients in an Underserved‐Inner City Population: A Single Tertiary Center Cohort
        date: 2020-07-03
       words: 3455
      flesch: 46
     summary: 11 Older age was established as risk factor for inpatient death in COVID-19 patients. 19, 20 However, another non-randomized study showed treatment with methylprednisolone decreased the risk of death among COVID-19 patients with ARDS.
    keywords: covid-19; death; inpatient; mortality; outcomes; patients; study
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        item: #1628 of 7819
          id: cord-269526-3npk3u5t
      author: Dehghanbanadaki, Hojat
       title: Bibliometric analysis of global scientific research on Coronavirus (COVID-19)
        date: 2020-05-23
       words: 3315
      flesch: 39
     summary: The global distribution of COVID-19 documents is depicted in Figure 1 . In addition, Table 1 lists the first top 10 countries in the number of COVID-19 documents as well In addition, to illustrate the international collaboration between all 125 countries that published COVID-19 documents, we considered the countries with at least 5 documents (n = 32).
    keywords: coronavirus; covid-19; documents; repeats
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        item: #1629 of 7819
          id: cord-269528-m8i1ss4w
      author: Poortmans, Philip M
       title: Cancer and COVID-19: what do we really know?
        date: 2020-05-29
       words: 741
      flesch: 36
     summary: International guidelines on radiation therapy for breast cancer during the COVID-19 Pandemic Recommendations for triage, prioritization and treatment of breast cancer patients during the COVID-19 pandemic Cancer care during the spread of coronavirus disease 2019 (COVID-19) in Italy: young oncologists' perspective Cancer patient management during the COVID-19 pandemic COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study Do Patients with cancer have a poorer prognosis of COVID-19? The oncology community has suddenly needed to protect a population assumed to be vulnerable from a potentially fatal infection, without jeopardising cancer treatments.
    keywords: cancer; covid-19; patients
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        item: #1630 of 7819
          id: cord-269537-h3lzl1un
      author: Banerjee, Aditi
       title: Crosstalk between endoplasmic reticulum stress and anti-viral activities: A novel therapeutic target for COVID-19
        date: 2020-05-23
       words: 2941
      flesch: 31
     summary: The Lancet Respiratory Medicine Pathology and pathogenesis of severe acute respiratory syndrome Endoplasmic Reticulum Stress in Disease Pathogenesis ER stress activates the NLRP3 inflammasome via an UPR-independent pathway Coronavirus infection, ER stress, apoptosis and innate immunity Endoplasmic reticulum stress and IRE-1 signaling cause apoptosis in colon cancer cells in response to andrographolide treatment The Role of Endoplasmic Reticulum Stress in Human Pathology Roles of endoplasmic reticulum stress in immune responses Insights Into the Role of Endoplasmic Reticulum Stress in Infectious Diseases The emerging roles of viroporins in ER stress response and autophagy induction during virus infection Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities Reverse genetic characterization of the natural genomic deletion in SARS-Coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein in-vitro and in-vivo Inhibitory effect of melatonin on lung oxidative stress induced by respiratory syncytial virus infection in mice Reactive Species in Viral Pneumonitis: Lessons From Animal Models Treatment of ebola and other infectious diseases: melatonin goes viral Melatonin induces anti-inflammatory effects via endoplasmic reticulum stress in RAW264.7 macrophages Melatonin modulates the autophagic response in acute liver failure induced by the rabbit hemorrhagic disease virus Inhibitory effect of melatonin on Mst1 ameliorates myocarditis through attenuating ER stress and mitochondrial dysfunction Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer Andrographolide suppresses proliferation of human colon cancer SW620 cells through the TLR4/NF-κB/MMP-9 signaling pathway Alterations of protein folding in the ER due to physiological stress such as disturbances in redox, Ca ++ levels, glycosylation or other environmental elements cause accumulation of misfolded proteins leading to ER stress.
    keywords: andrographolide; anti; cells; covid-19; infection; melatonin; sars; stress; virus
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        item: #1631 of 7819
          id: cord-269554-fzu6dy4e
      author: Hussein, M. H.
       title: Asthma in COVID-19: An extra chain fitting around the neck?
        date: 2020-07-15
       words: 3093
      flesch: 45
     summary: Univariate analysis revealed that asthma patients were more likely to be obese (75% vs 54.2%, p=0.001), with higher frequency of intubation (40.3% vs 27.8%, p = 0.036), and required longer duration of hospitalization (15.1{+/-}12.5 vs 11.5{+/-}10.6, p=0.015). We sought to analyze the effect of asthma on the disease progression and outcomes of COVID-19 patients.
    keywords: asthma; asthmatic; covid-19; license; medrxiv; outcomes; patients; preprint
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        item: #1632 of 7819
          id: cord-269559-gvvnvcfo
      author: Kergaßner, Andreas
       title: Memory-based meso-scale modeling of Covid-19: County-resolved timelines in Germany
        date: 2020-08-03
       words: 4497
      flesch: 48
     summary: The zoom-in clearly shows that county infections are dominated by their largest cities, following the three purple areas that represent Nürnberg, Fürth and Erlangen from bottom to top, underpinning our formulation of the cross-county infection terms (cf. We further assume that patients in courses (b) to (d) will be tested positive and are thereby considered in reported infection numbers.
    keywords: county; covid-19; data; disease; germany; infections; model; number; state
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        item: #1633 of 7819
          id: cord-269563-2979u47a
      author: Caetano Silva-Filho, José
       title: The influence of ABO blood groups on COVID-19 susceptibility and severity: a molecular hypothesis based on carbohydrate-carbohydrate interactions
        date: 2020-08-02
       words: 4621
      flesch: 29
     summary: Supported by an extensive bibliographic review highlighting (i) the mode of binding of SARS-CoV-2 to cell receptors, as well as (ii) the biochemical aspects of ABO blood group system and its association to infection and some circulatory conditions, we hypothesize that the influence of blood type on COVID-19 severity relies on the differential clustering of glycoproteins receptors to SARS-CoV-2 on host cell surface, induced by ABH antigens through carbohydrate-carbohydrate interactions with the glycan portions of these receptors, which could modulate virus binding to the target cell. In summary, this work proposes that the molecular mechanism underlying the influence of ABO blood groups on COVID-19 susceptibility and severity relies on carbohydrate-carbohydrate interactions between ABH antigens and sialoside glycans present on host cell receptors.
    keywords: abo; binding; blood; carbohydrate; cell; coronavirus; cov-2; covid-19; host; protein; sars; spike
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        item: #1634 of 7819
          id: cord-269566-mgzal1th
      author: Carmody, Sean
       title: When can professional sport recommence safely during the COVID-19 pandemic? Risk assessment and factors to consider
        date: 2020-05-07
       words: 1412
      flesch: 47
     summary: 6 ► WHO considerations for sports federations/sports event organisers when planning mass gatherings in the context of COVID-19. Minimise risk of transmission for all groups of sporting event participants.
    keywords: covid-19; event; risk
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        item: #1635 of 7819
          id: cord-269593-ipxwf4pv
      author: Aisenberg, Gabriel M.
       title: A message from the trench: A day in the hospital during the COVID-19 pandemic
        date: 2020-05-19
       words: 246
      flesch: 57
     summary: At this moment of the pandemic, we have learned that asymptomatic transmission occurs and that with adequate personal protective equipment (PPE) no one in our hospital caught the virus [2, 3] . r o o f distribution has almost become a cliché [1] ; yet, the pandemic created new challenges.
    keywords: covid-19
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        item: #1636 of 7819
          id: cord-269643-12qm4h9w
      author: Liu, Pai
       title: Dynamic interplay between social distancing duration and intensity in reducing COVID-19 US hospitalizations: A “law of diminishing returns”
        date: 2020-07-17
       words: 4910
      flesch: 42
     summary: In Fig. 5 , we highlight the diminishing marginal benefits of social distancing by plotting the maximum achievable reduction in y H as a function of social distancing duration (weeks). Semi-log plot for the relationship between social distancing duration and the corresponding maximum attainable decrease in medical demands for social distancing of various intensities.
    keywords: age; covid-19; demands; distancing; duration; epidemic; period; state; time
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        item: #1637 of 7819
          id: cord-269659-a1gf76bu
      author: Hong, W.
       title: Celebrex adjuvant therapy on COVID-19: An experimental study
        date: 2020-05-11
       words: 3097
      flesch: 50
     summary: The length of Celebrex treatment was determinate by the individual conditions. Our results indicated that Celebrex treatment with a conventional dose (0.2 g, twice a day) might effectively promote the recovery of ordinary and severe cases of COVID-19.
    keywords: cases; celebrex; covid-19; license; medrxiv; pge; preprint
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        item: #1638 of 7819
          id: cord-269690-6r2bfydw
      author: De Lorenzo, Rebecca
       title: Residual clinical damage after COVID-19: A retrospective and prospective observational cohort study
        date: 2020-10-14
       words: 4423
      flesch: 40
     summary: This is consistent with the hypothesis that SARS-CoV-2 infection may be associated with chronic cardiovascular damage [30] , and highlights the need of cardiovascular care in the management of COVID-19 patients. Among hospitalised patients, age ≥63 years, or age <63 plus non-invasive ventilation or diabetes identified those with the highest probability to need follow-up.
    keywords: age; analysis; covid-19; disease; follow; malnutrition; need; patients; ptsd
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        item: #1639 of 7819
          id: cord-269726-z0frgm7s
      author: Gidari, Anna
       title: Is recurrence possible in coronavirus disease 2019 (COVID-19)? Case series and systematic review of literature
        date: 2020-10-10
       words: 6714
      flesch: 47
     summary: Long-term effects of COVID-19 in a patient on maintenance dialysis Glucocorticoid-induced relapse of COVID-19 in a patient with sarcoidosis Reevaluation of retested nucleic acid-positive cases in recovered COVID-19 patients: Report from a designated transfer hospital in Chongqing Recurrence of positive SARS-CoV-2 RNA in COVID-19: a case report Clinical recurrences of COVID-19 symptoms after recovery: viral relapse, reinfection or inflammatory rebound? Positive SARS-CoV-2 RNA recurs repeatedly in a case recovered from COVID-19: dynamic results from 108 days of follow-up Persistent SARS-COV-2 RNA positivity in a patient for 92 days after disease onset: a case report Positive conversion of COVID-19 after two consecutive negative RT-PCR results: a role of low-dose CT Recurrent presence of SARS-CoV-2 RNA in a 33-year-old man Repositive cases of nucleic acid tests in discharged patients with COVID-19: a follow-up study Positive SARS-Cov-2 test in a woman with COVID-19 at 22 days after hospital discharge: a case report Low humoral immune response and ineffective clearance of SARS-Cov-2 in a COVID-19 patient with CLL during a 69-day follow-up Recurrent positive nucleic acid detection in a recovered COVID-19 patient: a case report and literature review Successful recovery of recurrence of positive SARS-CoV-2 RNA in COVID-19 patient with systemic lupus erythematosus: a case report and review Clinical characteristics of severe acute respiratory syndrome coronavirus 2 reactivation Absent immune response to SARS-CoV-2 in a 3-month recurrence of coronavirus disease 2019 (COVID-19) case Recurrence of SARS-CoV-2 infection with a more severe case after mild COVID-19, reversion of RT-qPCR for positive and late antibody response: case report Repeated COVID-19 relapse during post-discharge surveillance with viral shedding lasting for 67 days in a recovered patient infected with SARS-CoV-2 COVID-19 infection recurrence presenting with meningoencephalitis Post discharge positive re-tests in COVID-19: common but clinically non-significant Progressive CT findings and positive RT-PCR again of recovered and discharged patients with COVID-19 Changes in RT-PCR test results and symptoms during the menstrual cycle of female individuals infected with SARS-CoV-2: report of two cases Incidence, clinical course and risk factor for recurrent PCR positivity in discharged COVID-19 patients in Guangzhou, China: a prospective cohort study COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing The treatment and follow-up of 'recurrence' with discharged COVID-19 patients: data from Guizhou Recurrent recurrence of positive SARS-CoV-2 RNA in a COVID-19 patient Recurrence or relapse of COVID-19 in older patients: a description of three cases Recurrent pneumonia in a patient with new coronavirus infection after discharge from hospital for insufficient antibody production: a case report A case presentation for positive SARS-CoV-2 RNA recurrence in a patient with a history of type 2 diabetes that had recovered from severe COVID-19 Clinical features of discharged COVID-19 patients with an extended SARS-CoV-2 RNA positive signal in respiratory samples The dilemma of COVID-19 recurrence after clinical recovery Persistent positivity and fluctuations of SARS-CoV-2 RNA in clinically-recovered COVID-19 patients Probable causes and risk factors for positive SARS-CoV-2 test in recovered patients: evidence from Brunei Darussalam Epidemiological characteristics of COVID-19 patients in convalescence period Chest CT study of fifteen COVID-19 patients with positive RT-PCR retest results after discharge Rate of re-positive RT-PCR test among patients recovered from COVID-19 Discontinuation of antiviral drugs may be the reason for recovered COVID-19 patients testing positive again Changes in serum virus-specific IgM/IgG antibody in asymptomatic and discharged patients with reoccurring positive COVID-19 nucleic acid test (RPNAT) Chest CT and clinical follow-up of discharged patients with COVID-19 in Wenzhou City A cluster of the Corona Virus Disease 2019 caused by incubation period transmission in Wuxi Re-positive coronavirus disease 2019 PCR test: could it be a reinfection? Diagnostic testing and screening for SARS-CoV-2 Growth kinetics of SARS-coronavirus in Vero E6 cells Detection and isolation of SARS-CoV-2 in serum, urine, and stool specimens of COVID-19 patients from the Republic of Korea Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement Positive result of Sars-Cov-2 in faeces and sputum from discharged patient with COVID-19 in Yiwu Song S Recurrence of positive SARS-CoV-2 viral RNA in recovered COVID-19 patients during medical isolation observation Positive RT-PCR test results in discharged COVID-19 patients: reinfection or residual Coronavirus disease (COVID-19) in a paucisymptomatic patient: Epidemiological and clinical challenge in settings with limited community transmission Seven discharged patients turning positive again for SARS-CoV-2 on quantitative RT-PCR Serial CT features in discharged COVID-19 patients with positive RT-PCR re-test A case series of recurrent viral RNA positivity in recovered COVID-19 Chinese patients The clinical features and outcomes of discharged coronavirus disease 2019 patients: a prospective cohort study Re-infection by COVID-19: a real threat for the future management of pandemia? Letter to the Editor: Three cases of re-detectable positive SARS-CoV-2 RNA in recovered COVID-19 Microbiol Infect Dis patients with antibodies Two cases of COVID-19 with positive salivary and negative pharyngeal or respiratory swabs at hospital discharge: a rising concern Persistent viral RNA positivity during recovery period of a patient with SARS-CoV-2 infection Recurrent PCR positivity after hospital discharge of people with coronavirus disease 2019 (COVID-19) Rehospitalization of a recovered coronavirus disease 19 (COVID-19) child with positive nucleic acid detection
    keywords: assay; cases; cov-2; covid-19; nasopharyngeal; patients; pcr; positive; recurrence; rna; sars; swab
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        item: #1640 of 7819
          id: cord-269771-hffxb7bm
      author: Cheung, Ka Shing
       title: Gastrointestinal Manifestations of SARS-CoV-2 Infection and Virus Load in Fecal Samples from the Hong Kong Cohort and Systematic Review and Meta-analysis
        date: 2020-04-03
       words: 4805
      flesch: 38
     summary: We previously reported the high prevalence of enteric symptoms in patients with SARS and demonstrated acute viral replication in the small intestinal mucosa of SARS patients. The sewage concentrates of two hospitals receiving SARS patients in Beijing were also found to have SARS-CoV RNA detected at that time.
    keywords: clinical; coronavirus; covid-19; gastrointestinal; patients; rna; sars; stool; symptoms; viral
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        item: #1641 of 7819
          id: cord-269792-yth3t2cf
      author: Qiu, Ruijin
       title: Core Outcome Set for Clinical Trials of COVID-19 based on Traditional Chinese and Western Medicine
        date: 2020-03-27
       words: 3056
      flesch: 56
     summary: The COS include clinical outcomes (recovery/improvement/progression/death), etiology (SARS-CoV-2 nucleic-acid tests, viral load), inflammatory factor (C-reactive protein), vital signs (temperature, respiration), blood and lymphatic-system parameters (lymphocytes, virus antibody), respiratory outcomes (Pulmonary imaging, blood oxygen saturation, PaO2/FiO2 ratio, arterial blood gas analysis, mechanical ventilation, oxygen intake, pneumonia severity index), clinical efficacy (prevalence of preventing patients with mild-to-moderate disease progressing to severe disease), symptoms (clinical symptom score). When researchers report outcomes in a COS, they can also report other outcomes.
    keywords: consensus; cos; covid-19; outcomes; survey; trials
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        item: #1642 of 7819
          id: cord-269825-k685efoh
      author: Hu, Parker
       title: Early comprehensive testing for COVID-19 is essential to protect trauma centers
        date: 2020-07-01
       words: 3293
      flesch: 44
     summary: As additional cases were identified, all patients in the TBICU were moved to the Neurosurgical ICU which was repurposed to care for COVID-19 positive trauma patients. We recorded the daily number of trauma patients diagnosed with SARS-CoV-2 infection, the presence of clinical symptoms or radiological signs of COVID-19, and the results of verbal symptom screen (for new admissions).
    keywords: care; cov-2; covid-19; disease; infection; patients; sars; testing; trauma
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        item: #1643 of 7819
          id: cord-269826-l44xbgok
      author: Wills, Timothy T.
       title: Utilization of an Orthopedic Hood as Personal Protective Equipment for Intubation of Coronavirus Patients: a Brief Technical Report
        date: 2020-06-02
       words: 1305
      flesch: 44
     summary: In this brief technical report, we describe the integration of an orthopedic hood cover as an item for full barrier protection against COVID-19 transmission. We describe in a brief technical report the integration of an orthopedic hood cover as an item for full barrier protection against COVID-19 transmission during endotracheal intubation.
    keywords: covid-19; hood; intubation; ppe
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        item: #1644 of 7819
          id: cord-269827-h7qxodvh
      author: Mukhtar, Psychol. Sonia
       title: Mental Wellbeing of Nursing Staff during the COVID-19 Outbreak: A Cultural Perspective
        date: 2020-04-17
       words: 216
      flesch: 21
     summary: The mental health of medical workers in Wuhan, China dealing with the 2019 87 novel coronavirus Mukhtar S Mental Health and Emotional Impact of COVID-19: Applying Health Belief Model 90 for Medical Staff to General Public of Pakistan Brain Behav Immun National Health Commission of the People's Republic of China. During Intervention to promote physician well-being, job satisfaction, and 82 professionalism: a randomized clinical trial Responding to mental health needs after terror attacks Article l4828
    keywords: health
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        item: #1645 of 7819
          id: cord-269835-mz7i66qp
      author: Furfaro, Federica
       title: SFED recommendations for IBD endoscopy during COVID-19 pandemic: Italian and French experience
        date: 2020-06-11
       words: 7284
      flesch: 30
     summary: ESGE and ESGENA Position Statement on Gastrointestinal Endoscopy and the COVID-19 Pandemic Implications of COVID-19 for patients with pre-existing digestive diseases Practice of endoscopy during COVID-19 pandemic: position statements of the Asian Pacific Society for Digestive Endoscopy (APSDE-COVID statements) COVID-19 and gastrointestinal endoscopies: current insights and emergent strategies Endoscopy in inflammatory bowel diseases during the COVID-19 pandemic and postpandemic period Coronavirus COVID-19 Global Cases Report of the WHO-China Joint Mission on Coronavirus Disease Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study Sensitivity of nasopharyngeal, nasal and throat swab for the detection of SARS-CoV-2 Respiratory virus shedding in exhaled breath and efficacy of face masks Société Française d'Endoscopie Digestive. Nat Rev Gastroenterol Hepatol DOI: 10.1038/s41575-020-0319-3 sha: doc_id: 269835 cord_uid: mz7i66qp The current coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has required a complete change in the management of patients with inflammatory bowel disease (IBD) who need to undergo endoscopic procedures.
    keywords: bowel; colitis; cov-2; covid-19; crohn; disease; endoscopy; faecal; ibd; infection; pandemic; patients; risk; sars; symptoms
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        item: #1646 of 7819
          id: cord-269850-5pidolqb
      author: Maghdid, Halgurd S.
       title: A Smartphone Enabled Approach to Manage COVID-19 Lockdown and Economic Crisis
        date: 2020-08-14
       words: 5046
      flesch: 54
     summary: The approach is trying to preserve the privacy issue of the users (including public health users and infected users), since the system is exchanging data in a blind signature mechanism [16, 17] . For example, if the number of recorded of tracked users is wider and if the prediction model is intended to use for a bigger city includes New Work city in United State or London in United Kingdom; also, using deep learning algorithms rather than of using only K-Means algorithm.
    keywords: approach; area; contact; covid-19; lockdown; people; system; tracing; users
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        item: #1647 of 7819
          id: cord-269856-6h3j89wn
      author: Paolo Fadini, Gian
       title: Newly-diagnosed diabetes and admission hyperglycemia predict COVID-19 severity by aggravating respiratory deterioration
        date: 2020-08-15
       words: 3942
      flesch: 37
     summary: We evaluated which of these parameters explained the association between glucose levels and COVID-19 severity outcome (i.e. being mediators). We then evaluated whether these correlations could partially explain (i.e. mediate) the association between FPG and COVID-19 severity outcome.
    keywords: admission; association; covid-19; diabetes; outcome; patients; pre; severity
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        item: #1648 of 7819
          id: cord-269873-4hxwo5kt
      author: R., Mohammadi
       title: Transfer Learning-Based Automatic Detection of Coronavirus Disease 2019 (COVID-19) from Chest X-ray Images
        date: 2020-10-01
       words: 3388
      flesch: 49
     summary: An introduction to receiver operating characteristics curves Covidxnet: A framework of deep learning classifiers to diagnose covid-19 in x-ray images COVID-Net: A Tailored Deep Convolutional Neural Network Design for Detection of COVID-19 Cases from Chest X-Ray Images Covid-19: automatic detection from X-ray images utilizing transfer learning with convolutional neural networks A deep learning algorithm using CT images to screen for Corona Virus Disease (COVID-19) Deep Learning-based Detection for COVID-19 from Chest CT using Weak Label None The radiologists consider chest X-ray images over CT-scan as primary radiography examination to detect the infection caused by COVID-19
    keywords: chest; covid-19; images; learning; models; ray
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        item: #1649 of 7819
          id: cord-269895-a4xja2t5
      author: Chen, Xue-Yan
       title: TNFα inhibitor may be effective for severe COVID-19: learning from toxic epidermal necrolysis
        date: 2020-05-21
       words: 2241
      flesch: 38
     summary: The historical results of COVID-19 severe patients suggested diffuse alveolar damage. key: cord-269895-a4xja2t5 authors: Chen, Xue-Yan; Yan, Bing-Xi; Man, Xiao-Yong title: TNFα inhibitor may be effective for severe COVID-19: learning from toxic epidermal necrolysis date: 2020-05-21 journal: Ther Adv Respir Dis DOI: 10.1177/1753466620926800 sha: doc_id: 269895 cord_uid: a4xja2t5 Increased inflammatory cytokines [such as tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6)] are observed in COVID-19 patients, especially in the severe group.
    keywords: cells; covid-19; epidermal; group; necrolysis; patients
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        item: #1650 of 7819
          id: cord-269900-7mzyib4r
      author: Ierardi, Anna Maria
       title: How to Handle a COVID-19 Patient in the Angiographic Suite
        date: 2020-04-10
       words: 3447
      flesch: 44
     summary: Execution of IR procedures in situations with suspected airborne infections needs particular precautions to reduce the risk of transmission to the healthcare workers. The same scheme has been adopted for interventional radiologists: per week only 5 (2 for neuro and 3 for body) go to the hospital where they cover IR procedures and replace the peripherally inserted central catheter (Picc) team for COVID-19 and non-COVID-19 patients (Picc team is now employed in 'COVID-area').
    keywords: covid-19; equipment; patients; ppe; procedures; room; services; staff
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        item: #1651 of 7819
          id: cord-269909-1cso5cl4
      author: Amatya, Shaili
       title: Management of newborns exposed to mothers with confirmed or suspected COVID-19
        date: 2020-05-21
       words: 5556
      flesch: 39
     summary: More definitive evidence is needed An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infections and pregnancy outcomes Potential maternal and infant outcomes from coronavirus 2019-nCoV (SARS-CoV-2) infecting pregnant women: Lessons from SARS, MERS, and other human coronavirus infections Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Coronavirus disease 2019 (COVID-19) during pregnancy: a case series Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia Coronavirus in pregnancy and delivery: rapid review A case report of neonatal COVID-19 infection in China Perinatal transmission of COVID-19 associated SARS-CoV-2: should we worry? For symptomatic PUIs and COVID-19 infected newborns, additional tests such as CBC and CRP should be performed, as well as other tests that are clinically indicated [15] .
    keywords: care; children; coronavirus; cov-2; covid-19; disease; infection; mothers; neonatal; neonates; newborns; patients; risk; sars
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        item: #1652 of 7819
          id: cord-269914-75to9xr2
      author: Jansson, Miia
       title: Artificial Intelligence for clinical decision support in Critical Care, required and accelerated by COVID-19
        date: 2020-10-21
       words: 1363
      flesch: 25
     summary: A Systematic Review Cardiorespiratory dynamics measured from continuous ECG monitoring improves detection of deterioration in acute care patients: a retrospective cohort study Predicting sequences of clinical events by using a personalized temporal latent embedding model Optimal intensive care outcome prediction over time using machine learning Modified SEIR and AI prediction of the epidemics trend of COVID-19 in China under public health interventions Transfer Learning with Deep Convolutional Neural Network (CNN) for Pneumonia Detection using Chest X-ray Automated detection of COVID-19 cases using deep neural networks with X-ray images A systematic review of CT chest in COVID-19 diagnosis and its potential application in a surgical setting A new role for Biofoundries in rapid prototyping, development, and validation of automated clinical diagnostic tests for SARS-CoV-2 Robot-assisted therapy using the MOTOmed letto 2 for the integrated early rehabilitation of stroke patients admitted to the intensive care unit Current utilization and future directions of robotic-assisted endovascular surgery Automated tracheal intubation in an airway manikin using a robotic endoscope: a proof of concept study Diagnosis of ventilator-associated pneumonia using electronic nose sensor array signals: solutions to improve the application of machine learning in respiratory research 1+ Million Genomes Initiative Determinantes Genéticos y Biomarcadores genómicos de riesgo en pacientes con infección por coronavirus SARS-COV-2 Using whole genome sequencing to help combat COVID-19 Digi-HTA: Health technology assessment framework for digital healthcare services The clinical artificial intelligence department: a prerequisite for success AI, big data, and machine learning can help health care systems respond to these unprecedented challenges.
    keywords: care; covid-19; learning; models; patients; prediction
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        item: #1653 of 7819
          id: cord-269958-nj0ub9in
      author: Woods, Eric Taylor
       title: COVID‐19, nationalism, and the politics of crisis: A scholarly exchange
        date: 2020-07-19
       words: 10582
      flesch: 45
     summary: Greenfeld argues that ethnic nationalism is a key variable shaping the responses of many states to COVID-19 when compared with previous pandemics such as H1N1. In the monotheistic civilization alone, in which ethnic nationalism is indeed the most common type, there exist two other types of nationalism: individualistic nationalism (such as the original English one) and collectivistic-civic nationalism (such as the French).
    keywords: anti; china; chinese; conflict; covid-19; crisis; global; government; greenfeld; nationalism; new; pandemic; people; states; united; united states; virus; world
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        item: #1654 of 7819
          id: cord-269969-xl1ooxoj
      author: Duong, Tuyen Van
       title: Digital Healthy Diet Literacy and Self-Perceived Eating Behavior Change during COVID-19 Pandemic among Undergraduate Nursing and Medical Students: A Rapid Online Survey
        date: 2020-09-30
       words: 4143
      flesch: 41
     summary: 2020-2030 Strategic Plan for NIH Nutrition Research: A Report of the NIH Nutrition Research Task Force Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections Nutritional status, diet and viral respiratory infections: Perspectives for SARS-CoV-2 Metabolic Impacts of Confinement during the COVID-19 Pandemic Due to Modified Diet and Physical Activity Habits The impact of nutrition on COVID-19 susceptibility and long-term consequences The rise of eating disorders in Asia: A review Health effects of dietary risks in 195 countries, 1990-2017: A systematic analysis for the Global Burden of Disease Study Non-communicable diseases, food and nutrition in Vietnam from 1975 to 2015: The burden and national response Risk of disordered eating attitudes and its relation to mental health among university students in ASEAN Infodemic and Emerging Issues through a Data Lens: The Case of China Coronavirus-Related Health Literacy: A Cross-Sectional Study in Adults during the COVID-19 Infodemic in Germany COVID-19: Health literacy is an underestimated problem COVID-19 pandemic, infodemic and the role of eHealth literacy A Bold Response to the COVID-19 Pandemic: Medical Students, National Service, and Public Health Medical student involvement in the COVID-19 response WAB team instead of SWAT team -students as front-line force during the COVID-19 Pandemic Medical students for health-care staff shortages during the COVID-19 pandemic Top Concerns of Tweeters During the COVID-19 Pandemic: Infoveillance Study Conversations and Medical News Frames on Twitter: Infodemiological Study on COVID-19 in South Korea Electronic health-literacy skills among nursing students The Associations among Individual Factors, eHealth Literacy, and Health-Promoting Lifestyles among College Students Healthy diet: Health impact, prevalence, correlates, and interventions Individual risk management strategy and potential therapeutic options for the COVID-19 pandemic Potential interventions for Novel Coronavirus in China: A systematic review A Comprehensive Literature Review on the Clinical Presentation, and Management of the Pandemic Coronavirus Disease 2019 (COVID-19) Micronutrients as immunomodulatory tools for COVID-19 management Environmental and nutritional impacts of dietary changes in Spain during the COVID-19 lockdown Fear of COVID-19 Scale-Associations of Its Scores with Health Literacy and Health-Related Behaviors among Medical Students Overview of Novel Coronavirus (2019-nCoV) Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation Development and validation of a new short-form health literacy instrument (HLS-SF12) for the general public in six Asian countries Validation of the short-form health literacy questionnaire (HLS-SF12) and its determinants among people living in rural areas in Vietnam Factors associated with health literacy among the elderly people in Vietnam People with suspected COVID-19 symptoms were more likely depressed and had lower health-related quality of life: The potential benefit of health literacy Health literacy and public health: A systematic review and integration of definitions and models Measuring health literacy in populations: Illuminating the design and development process of the European Health Literacy Survey Questionnaire (HLS-EU-Q) Comparative Report of Health Literacy in Eight EU Member States. In this study, our findings illustrate that higher scores of health literacy and digital healthy diet literacy were positively associated with healthier eating behavior during the pandemic for both nursing and medical students.
    keywords: covid-19; ddl; diet; eating; health; literacy; medical; pandemic; scale; students
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        item: #1655 of 7819
          id: cord-269970-tnnpo6hu
      author: Musa, Hassan H
       title: L’impact psychologique silencieux de la pandémie de COVID-19 au Soudan
        date: 2020-10-14
       words: 1114
      flesch: 39
     summary: From the first reported cases to September 7, 2020, 13,437 confirmed COVID-19 cases, and 833 deaths have been reported in Sudan In Sudan, when the first coronavirus positive case was reported, Sudan faced critical challenges, such as the identification of positive cases through testing, insufficient number of health care workers to treat confirmed COVID-19 cases, and implementation of treatment plans in response to COVID-19 [8] .
    keywords: covid-19; health; pandemic; sudan
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        item: #1656 of 7819
          id: cord-269972-p9lbgxr4
      author: Imoto, W
       title: Coronavirus disease with multiple infarctions
        date: 2020-10-01
       words: 689
      flesch: 39
     summary: Anticoagulant treatment with heparin reduces mortality in COVID-19 patients with high D-dimer or high sepsis-induced coagulopathy (SIC) score 5 ; this suggests that infarctions may be an important factor associated with mortality in COVID-19 patients. Clinicians should be aware that infarction, an important lifethreatening complication, may occur in any organ, and early anti-thromboembolism treatment should be considered in COVID-19 patients.
    keywords: covid-19; infarction; patients
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        item: #1657 of 7819
          id: cord-269981-xm0by310
      author: Shen, Cheng
       title: Perioperative preparation in thoracic day surgery: Battle against COVID‐19
        date: 2020-06-17
       words: 1664
      flesch: 44
     summary: Patients have to visit appropriate specialist clinics to evaluate whether they qualify for thoracic day surgery. Patients should also meet the standard requirements for thoracic day surgery, including patient age (≤55 years), diameter of the pulmonary nodule on thoracic CT scan (≤3 cm) for early stage lung cancer or benign pulmonary nodule patient, and an ASA status of 1 or 2.
    keywords: covid-19; day; infection; patients; surgery; thoracic
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        item: #1658 of 7819
          id: cord-270011-fmetxqqf
      author: Lasheras, Isabel
       title: Uso de antipalúdicos en el tratamiento del COVID-19: ¿una ventana de oportunidad?
        date: 2020-04-22
       words: 2290
      flesch: 23
     summary: En cualquier caso, actualmente se está llevando a cabo un estudio multinacional sobre el perfil de la seguridad de la hidroxicloroquina Si bien los criterios de alta variaron durante el ingreso por el incremento de la presión asistencial, es llamativo que un 81.3% de los pacientes recibieron el alta en una media de 4.1 días desde el inicio de la terapia, y 4.6 días desde el ingreso, con una puntuación baja en la escala de NEWS, que estima la presencia de enfermedad; permaneciendo un 16.2% y un 1.2% de los pacientes hospitalizados en el área de infecciosas y la UCI respectivamente, y falleciendo durante el estudio sólo un paciente de 86 años que había ingresado con una neumonía avanzada.
    keywords: con; covid-19; del; hidroxicloroquina; las; los; pacientes; para; por; que; sobre; una; uso
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        item: #1659 of 7819
          id: cord-270019-er70ehk4
      author: Yang, Kunyu
       title: Clinical characteristics, outcomes, and risk factors for mortality in patients with cancer and COVID-19 in Hubei, China: a multicentre, retrospective, cohort study
        date: 2020-05-29
       words: 4271
      flesch: 44
     summary: First case of 2019 novel coronavirus in the United States Transmission of 2019-nCoV infection from an asymptomatic contact in Germany COVID-19) pandemic Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Epidemic situation of COVID-19 (in Chinese) There should be no ESKAPE for febrile neutropenic cancer patients: the dearth of effective antibacterial drugs threatens anticancer efficacy Diagnostic strategy for hematology and oncology patients with acute respiratory failure: randomized controlled trial Infectious complications in patients with chronic lymphocytic leukemia: pathogenesis, spectrum of infection, and approaches to prophylaxis Acute respiratory distress syndrome in patients with malignancies Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected: interim guidance Clinical characteristics of coronavirus disease 2019 in China International Severe Acute Respiratory and emerging Infection Consortium. Patients with haematological malignancies were younger than those with solid tumours ( of 177 patients) were more frequently seen in patients with haematological malig nancies than in those with solid tumours.
    keywords: cancer; clinical; covid-19; data; hospital; onset; patients; risk; study; weeks
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        item: #1660 of 7819
          id: cord-270021-8obqdbh9
      author: Percy, Edward
       title: Post-Discharge Cardiac Care in the Era of Coronavirus 2019: How Should We Prepare?
        date: 2020-04-09
       words: 1918
      flesch: 34
     summary: In Canada, post-acute cardiac care includes outpatient and inpatient cardiac rehabilitation facilities, long-term care hospitals, and nursing homes. The objectives of this manuscript are to describe the current status of post-acute cardiac care in Canada, and to provide suggestions with regard to the steps that policymakers and healthcare organizations can take to achieve preparedness in this area, in order to reduce care fragmentation in the post-COVID-19 era.
    keywords: acute; care; covid-19; patients; rehabilitation
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        item: #1661 of 7819
          id: cord-270046-bxtez39p
      author: Bourion-Bédès, Stéphanie
       title: Psychological impact of the COVID-19 outbreak on students in a French region severely affected by the disease: results of the PIMS-CoV 19 study
        date: 2020-11-05
       words: 4431
      flesch: 41
     summary: Furthermore, several characteristics of the students' living conditions were associated with student anxiety. The study aimed to assess the prevalence of anxiety and identify the factors associated with anxiety among French students during lockdown.
    keywords: anxiety; covid-19; factors; health; students; study; support
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        item: #1662 of 7819
          id: cord-270079-vwnzp6zj
      author: Galanis, Nikiforos
       title: Coagulopathy in COVID-19 infection: a case of acute upper limb ischemia
        date: 2020-07-02
       words: 1266
      flesch: 35
     summary: He was admitted to G. Papanikolaou General Hospital in Thessaloniki, a tertiary hospital set as a reference center for COVID-19 patients. key: cord-270079-vwnzp6zj authors: Galanis, Nikiforos; Stavraka, Chara; Agathangelidis, Filon; Petsatodis, Evangelos; Giankoulof, Christos; Givissis, Panagiotis title: Coagulopathy in COVID-19 infection: a case of acute upper limb ischemia date: 2020-07-02 journal: J Surg Case Rep DOI: 10.1093/jscr/rjaa204 sha: doc_id: 270079 cord_uid: vwnzp6zj Coagulation abnormalities and thrombosis have been recently identified as sequelae of severe infection with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
    keywords: coagulopathy; covid-19; infection; patients
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        item: #1663 of 7819
          id: cord-270083-gm8i9olj
      author: Jang, Jong Geol
       title: Prognostic Factors for Severe Coronavirus Disease 2019 in Daegu, Korea
        date: 2020-06-02
       words: 2716
      flesch: 49
     summary: There have been no studies regarding prognostic factors for severe disease in COVID-19 patients in Korea. In a recent study, COVID-19 patients without other comorbidities but with diabetes were shown to be at greater risk of severe disease as assessed by organ damage, inflammatory factors, and hypercoagulability.
    keywords: covid-19; diabetes; disease; factors; group; patients
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        item: #1664 of 7819
          id: cord-270112-o2exvfy5
      author: Ferrarese, Carlo
       title: An Italian multicenter retrospective-prospective observational study on neurological manifestations of COVID-19 (NEUROCOVID)
        date: 2020-05-19
       words: 2467
      flesch: 26
     summary: The estimate of the prevalence of neurological manifestations and the estimate of the risk of developing them will be calculated overall and for specific disorders, along with the corresponding 95% confidence intervals (using the total of COVID-19 patients in the centers involved in the study). Indeed, neurologists need to pay close attention to COVID-19 neurological manifestations, which may have contributed to their demise, especially for those with severe infections.
    keywords: covid-19; data; manifestations; patients; sars; study
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        item: #1665 of 7819
          id: cord-270116-r2rnnsfh
      author: Lippi, Giuseppe
       title: Current laboratory diagnostics of coronavirus disease 2019 (COVID-19)
        date: 2020-05-11
       words: 4754
      flesch: 22
     summary: As concerns serological testing, promising information can be garnered from preliminary investigations, showing that the vast majority of COVID-19 patients seem to develop a sustained immune response against the virus, characterized especially by emergence of anti-SARS-CoV-2 IgG and IgA, 1 to 2 weeks after the onset of fever and/or respiratory symptoms. Guo et al have first shown that the median time of antibodies appearance in serum or plasma of COVID-19 patients begins 3-6 days after the onset of symptoms for both IgM and IgA, whilst it is delayed to 10-18 days for IgG (42) .
    keywords: antibodies; clinical; coronavirus; cov-2; covid-19; disease; laboratory; patients; sars; tests
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        item: #1666 of 7819
          id: cord-270122-xijsj0d8
      author: Hogan, Robert Edward
       title: COVID-19 in Patients With Seizures and Epilepsy: Interpretation of Relevant Knowledge of Presenting Signs and Symptoms
        date: 2020-08-24
       words: 1641
      flesch: 32
     summary: However, relative lack of cohort studies in patients with a history of epileptic seizures limit conclusions about effects of COVID-19 patients with epilepsy. Despite findings from studies in the general population, there is great heterogeneity of neurological presentation for individual patients with viral illnesses, so a minority of COVID-19 patients may present with neurological signs and symptoms.
    keywords: covid-19; epilepsy; patients; seizures
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        item: #1667 of 7819
          id: cord-270124-tqhkzd2w
      author: Campos, Fábio Guilherme
       title: General recommendations to the colorectal surgeon during the COVID-19 pandemic
        date: 2020-06-19
       words: 2198
      flesch: 39
     summary: ACS COVID-19 and Surgery The Royal College of Surgeons Updated Intercollegiate General Surgery Guidance on COVID-19 Coronavirus pandemic and colorectal surgery: practical advice based on the Italian experience Digestive Symptoms in COVID-19 Patients With Mild Disease Severity: In suspected patients, utmost care should be taken when handling stool in the rectal ampoule.
    keywords: covid-19; infection; pandemic; patients; procedures; recommendations; surgery
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        item: #1668 of 7819
          id: cord-270184-bq5p2gs6
      author: Alrubaiee, Gamil Ghaleb
       title: Knowledge, attitudes, anxiety, and preventive behaviours towards COVID-19 among health care providers in Yemen: an online cross-sectional survey
        date: 2020-10-13
       words: 5572
      flesch: 46
     summary: Part (1) the socio-demographic characteristics such as age, sex, occupation, education level, years of working experience, and sources of COVID-19 related knowledge. Interesting, the current study indicated lower anxiety level results compared to other studies that were carried out during the outbreak as reported by Huang and Zhao
    keywords: anxiety; attitude; behaviours; covid-19; hcps; knowledge; level; respondents; study
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        item: #1669 of 7819
          id: cord-270214-5bjow148
      author: Tan, Winson Jianhong
       title: Safe Colorectal Surgery in the COVID-19 Era – A Singapore Experience
        date: 2020-04-30
       words: 1837
      flesch: 43
     summary: While the measures we have in place have allowed safe colorectal surgery, there are several modifications that may have to be considered in view of increasing community transmission and recognition of presymptomatic transmission. For COVID-19 cases, surgery is performed in a dedicated negative pressure OR.
    keywords: cases; covid-19; patients; procedures; surgery; transmission
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        item: #1670 of 7819
          id: cord-270232-ln7iil5y
      author: Bergman, Yoav S.
       title: COVID-19 health worries and anxiety symptoms among older adults: the moderating role of ageism
        date: 2020-06-17
       words: 2443
      flesch: 45
     summary: key: cord-270232-ln7iil5y authors: Bergman, Yoav S.; Cohen-Fridel, Sara; Shrira, Amit; Bodner, Ehud; Palgi, Yuval title: COVID-19 health worries and anxiety symptoms among older adults: the moderating role of ageism date: 2020-06-17 journal: Accordingly, the current study examined the moderating role of COVID-19-related ageism in the connection between COVID-19 health worries and anxiety symptoms among older adults.
    keywords: adults; ageism; anxiety; covid-19; symptoms
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        item: #1671 of 7819
          id: cord-270238-5esd2eti
      author: Tian, T.
       title: Risk factors associated with mortality of COVID-19 in 2692 counties of the United States
        date: 2020-05-21
       words: 2509
      flesch: 57
     summary: The details about those factors are available on the official website of county health ranking and roadmaps program(8). R news Negative binomial regression Regression models for count data in R We would like to thank all individuals who are collecting epidemiological data of the COVID-19 outbreak, and people collecting health ranking county data in the county health ranking and roadmaps program. .
    keywords: counties; license; medrxiv; perpetuity; preprint
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        item: #1672 of 7819
          id: cord-270245-zziwb2jy
      author: Russell, Beth
       title: Factors Affecting COVID-19 Outcomes in Cancer Patients: A First Report From Guy's Cancer Center in London
        date: 2020-07-22
       words: 4115
      flesch: 42
     summary: In this analysis of our data, we had three aims: 1) To describe demographic and clinical characteristics of COVID-19 positive cancer patients, in terms of their COVID-19 and cancer diagnoses. There was a non-statistically significant indication that those patients who were diagnosed with cancer more than 24 months ago were at a higher risk of presenting with severe COVID-19 as compared to those diagnosed during the last 24 months Using multivariate modeling based on a directed acyclic graph, this study reports on a large cohort of COVID-19 positive cancer patients from a single institution.
    keywords: cancer; clinical; cohort; covid-19; death; patients; severity; study; treatment
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        item: #1673 of 7819
          id: cord-270249-miys1fve
      author: Liu, Xianbo
       title: COVID-19: data-driven dynamics, statistical and distributed delay models, and observations
        date: 2020-08-06
       words: 8127
      flesch: 51
     summary: The nonlinear distributed delay systems given by Eqs. (3), (4) provide a feasible mathematical framework to describe the evolution of COVID-19 infection dynamics as well as for modeling the control performances associated with quarantine and other measures. (ii) The improved SEIQR model with time-varying infection rate and distributed delays is found to be better suited for understanding COVID-19 infection dynamics with and without control measures.
    keywords: cases; covid-19; data; dynamics; fig; function; infection; measures; model; system; time
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        item: #1674 of 7819
          id: cord-270254-dp7z1kla
      author: Inzitari, Marco
       title: How a Barcelona post-acute facility became a referral center for comprehensive management of subacute patients with COVID-19
        date: 2020-06-11
       words: 828
      flesch: 23
     summary: Brief Summary: The paper describes how a large post-acute care facility in 23 Barcelona, was adapted at the outbreak of the COVID 19 pandemic to become 24 a polyvalent reference center for older COVID-19 patients assessed as not 25 requiring intensive care. Management of the situation requires a systemic response, and post-acute care (PAC) can provide an adequate mix of active treatment, management of associated geriatric syndromes and palliative care, both in the acute phase, and in post-COVID-19 recovery.
    keywords: acute; care; covid-19; patients
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        item: #1675 of 7819
          id: cord-270290-i4p4p0o4
      author: Ruamviboonsuk, Paisan
       title: Chloroquine and Hydroxychloroquine Retinal Toxicity Consideration in the Treatment of COVID-19
        date: 2020-04-29
       words: 1717
      flesch: 45
     summary: Nonetheless, it has been reported that retinal toxicity can develop even after <1 year of high dose of HCQ use (1000 mg daily) in an oncology trial. Asia Pac J Ophthalmol (Phila) DOI: 10.1097/apo.0000000000000289 sha: doc_id: 270290 cord_uid: i4p4p0o4 The proposed doses of chloroquine (CQ) and hydroxychloroquine (HCQ) for treatment of COVID-19 (1000 mg/day for 10 days, CQ; 800 mg first day then 400 mg/day for 5 days, HCQ) in many guidelines worldwide, are considerably higher than the maximum recommended daily safe doses of both agents (≤2.3 mg/kg/day, CQ; ≤5.0 mg/kg/day, HCQ) for development of retinal toxicity.
    keywords: covid-19; hcq; toxicity; treatment
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        item: #1676 of 7819
          id: cord-270322-jkvo8s3f
      author: Singh, Jasvinder A.
       title: Gout management and outcomes during the COVID-19 pandemic: a cross-sectional internet survey
        date: 2020-10-14
       words: 3408
      flesch: 39
     summary: More regular use of gout medication was reported during the COVID-19 pandemic: allopurinol, 44%; colchicine, 37%; non-steroidal anti-inflammatory drugs, 36%. Compared with no/mild psychological distress, moderate–severe psychological distress during the COVID-19 pandemic was significantly associated with more difficulty getting gout medication filled (p = 0.02), flares treated (p = 0.005), and receiving gout education (p = 0.001).
    keywords: covid-19; distress; gout; pandemic; respondents; study; survey
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        item: #1677 of 7819
          id: cord-270327-v4td3zsa
      author: Atallah, Bassam
       title: A Marker of Systemic Inflammation or Direct Cardiac Injury: Should Cardiac Troponin Levels be Monitored in COVID-19 Patients?
        date: 2020-04-29
       words: 1692
      flesch: 38
     summary: Interestingly, the median time from illness onset to acute cardiac injury among nonsurvivors was 14.5 days, compared to only one incidence of acute cardiac injury in survivors, which took place 21 days post-illness onset. Cardiologists as well as multidisciplinary teams involved in the care of COVID-19 patients are encouraged to participate in cardiac registries such as CAPACITY-COVID to better our collective understanding of the disease's implications.
    keywords: cardiac; covid-19; disease; levels; patients
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        item: #1678 of 7819
          id: cord-270336-x1up9nvp
      author: Filatov, Asia
       title: Neurological Complications of Coronavirus Disease (COVID-19): Encephalopathy
        date: 2020-03-21
       words: 1134
      flesch: 48
     summary: Current evidence suggests that COVID-19 patients commonly had neurological symptoms manifested as acute stroke (6%), consciousness impairment (15%), and skeletal muscle injury (19%) Neurological complications in COVID-19 infected patients have not been widely reported.
    keywords: covid-19; patient; symptoms
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        item: #1679 of 7819
          id: cord-270399-yfko8mpc
      author: Foster, Allison
       title: It’s complicated: A case report on a COVID-19-positive HIV patient presenting with rhabdomyolysis and acute kidney injury
        date: 2020-10-15
       words: 3402
      flesch: 42
     summary: Recent studies have demonstrated that approximately 20%-40% of COVID-19 patients admitted to the intensive care unit (ICU) develop acute kidney injury (AKI). In a recent histopathologic examination of COVID-19 patients, 9 SARS-CoV-2-associated pulmonary lesions manifest as inflammation of the parenchyma and interstitium, with hyperplasia of the alveolar epithelium and formation of hyaline membranes.
    keywords: aki; cov-2; covid-19; hiv; injury; kidney; patient; sars
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        item: #1680 of 7819
          id: cord-270419-krrd074l
      author: Falkenhain‐López, Daniel
       title: SARS‐Coronavirus‐2 and acute urticaria
        date: 2020-05-22
       words: 343
      flesch: 44
     summary: Simultaneously, she developed widespread pruritic evanescent skin lesions (lasting <24 hours). However, this association with virus infections has rarely been reported in the literature.
    keywords: covid-19; urticaria
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        item: #1681 of 7819
          id: cord-270422-2xqptne5
      author: Kobsa, Serge
       title: Commentary: A Pandemic Blueprint for Planning Your Act and Acting Your Plan
        date: 2020-09-18
       words: 436
      flesch: 47
     summary: An interactive web-based dashboard to track COVID-19 in real time Institutional preparedness strategies for heart failure patients during the COVID-19 pandemic The rapid transformation of cardiac surgery practice in the coronavirus disease 2019 (COVID-19) pandemic: Insights and clinical strategies from a center at the epicenter Characteristics and Outcomes of Recipients of Heart Transplant With Coronavirus Disease Anesthesiologists as perioperative leaders Transition of a Large Tertiary Heart Failure Program in Response to the COVID-19 Pandemic: In this context, importance of team building in non-pandemic time cannot be underestimated, and perhaps such effort is more essential than attempting to forecast the unpredictable.
    keywords: pandemic; plan
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        item: #1682 of 7819
          id: cord-270425-1ughypnx
      author: Louis-Jean, James
       title: Coronavirus (COVID-19) and Racial Disparities: a Perspective Analysis
        date: 2020-10-06
       words: 3738
      flesch: 46
     summary: Many African Americans infected with syphilis were promised treatment from the Public Health Department. Program Limitations in the use of race in the study of disease causation Seeking causal explanations in social epidemiology Socio-ecological stress, suppressed hostility, skin color, and black-white male blood pressure: Detroit Preliminary estimates of the prevalence of selected underlying health conditions among patients with Coronavirus Disease 2019 -United States Vital signs: racial disparities in age-specific mortality among blacks or African Americans -United States At the dark end of the street: black women, rape, and resistance-a new history of the civil rights movement from Rosa parks to the rise of black power From slavery to freedom: a history of African Americans Who is Homeless?
    keywords: african; americans; communities; covid-19; health; healthcare; pandemic; usa; virus
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        item: #1683 of 7819
          id: cord-270465-9jp0xw7j
      author: Ono, Yoshitaka
       title: Asthma exacerbation associated with COVID-19 pneumonia
        date: 2020-07-27
       words: 1021
      flesch: 40
     summary: She was diagnosed with asthma exacerbation and COVID-19 pneumonia. Information is also limited on whether COVID-19 can cause asthma exacerbation and on treatment of asthma exacerbation accompanied by COVID-19.
    keywords: asthma; covid-19; exacerbation; patients
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        item: #1684 of 7819
          id: cord-270467-es6dnx36
      author: Frisardi, Vincenza
       title: Commentary: Coronavirus and Obesity: Could Insulin Resistance Mediate the Severity of Covid-19 Infection?
        date: 2020-07-07
       words: 1257
      flesch: 37
     summary: In the last few decades, insulin was believed to intervene in other degenerative diseases both as a principal leading factor and in a cross-talk with other metabolic disorders (3, 4). Nevertheless, other clinical expressions of SARS-CoV2 were reported, suggesting an interesting hypothesis about the host-pathogen interaction via the metabolism 1 .
    keywords: covid-19; insulin; obesity; patients
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        item: #1685 of 7819
          id: cord-270474-jaurhjvr
      author: Xiang, Zhen
       title: Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels
        date: 2020-06-27
       words: 4425
      flesch: 42
     summary: We verified the efficacy of nine chemicals on regulating ACE2 expression in human GES-1, an upper digestive tract epithelial cell line, and THP-1, a human monocyte cell line, and found that several glucocorticoids imparted activating effects on ACE2 in both cell lines. The drugs triciribine and kinetin riboside activate ACE2 expression or inhibit IL-6 production in macrophages to some extent.
    keywords: ace2; cell; covid-19; effect; expression; glucocorticoids; human; hydrocortisone; il-6; macrophages
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        item: #1686 of 7819
          id: cord-270475-mkpn9tz6
      author: Requena, Manuel
       title: COVID-19 and Stroke: incidence and etiological description in a high-volume center.
        date: 2020-08-05
       words: 2428
      flesch: 42
     summary: Our aim is to uncover the rate of acute stroke in COVID-19 patients and identify those cases in which a possible causative relationship could exist. Our aim is to uncover the rate of acute stroke in COVID-19 patients admitted in a highvolume center and identify those cases in which a possible causative relationship could exist.
    keywords: covid-19; hospital; infection; patients; risk; sars; stroke
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        item: #1687 of 7819
          id: cord-270481-rrpqz0uy
      author: Hays, Russell
       title: Helminth coinfection and COVID-19: An alternate hypothesis
        date: 2020-08-17
       words: 1081
      flesch: 23
     summary: key: cord-270481-rrpqz0uy authors: Hays, Russell; Pierce, Doris; Giacomin, Paul; Loukas, Alex; Bourke, Peter; McDermott, Robyn title: Helminth coinfection and COVID-19: An alternate hypothesis date: 2020-08-17 journal: PLoS Negl Trop Dis DOI: 10.1371/journal.pntd.0008628 sha: doc_id: 270481 cord_uid: rrpqz0uy nan In their recently published commentary, Bradbury and colleagues [1] drew attention to the possible negative interactions between helminth infection and COVID-19 severity in helminth-endemic regions. Although the interaction between helminth infection and viral pneumonia is poorly defined, there is some evidence that helminth infection may moderate the process of pulmonary inflammation in viral infections.
    keywords: covid-19; helminth; infection
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        item: #1688 of 7819
          id: cord-270509-roc93m4f
      author: Radhakrishnan, Suma
       title: Guidelines for Surgical Tracheostomy and Tracheostomy Tube Change During the COVID-19 Pandemic: A Review Article
        date: 2020-06-22
       words: 1525
      flesch: 51
     summary: A range of cuffed non-fenestrated sets of tracheostomy tubes to be kept ready in OR and to be replaced after surgery. We also did explore the current literature and recommendations for tracheostomy in patients with COVID-19 and studied the previous data from severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1), the virus responsible for the SARS outbreak of 2003.
    keywords: covid-19; patients; tracheostomy; tube; ventilator
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        item: #1689 of 7819
          id: cord-270511-eugkdh6k
      author: Grossman, Ephraim S.
       title: COVID-19 related loneliness and sleep problems in older adults: Worries and resilience as potential moderators
        date: 2020-08-28
       words: 3075
      flesch: 50
     summary: key: cord-270511-eugkdh6k authors: Grossman, Ephraim S.; Hoffman, Yaakov S.G.; Palgi, Yuval; Shrira, Amit title: COVID-19 related loneliness and sleep problems in older adults: Worries and resilience as potential moderators date: 2020-08-28 journal: Pers Individ Dif DOI: 10.1016/j.paid.2020.110371 sha: doc_id: 270511 cord_uid: eugkdh6k OBJECTIVES: Participants completed measures of COVID-19 related loneliness, sleep problems, COVID-related worries, and resilience.
    keywords: covid-19; loneliness; problems; resilience; sleep; worries
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        item: #1690 of 7819
          id: cord-270518-750vhgwo
      author: Nappi, Carmela
       title: Effects of the COVID-19 pandemic on myocardial perfusion imaging for ischemic heart disease
        date: 2020-08-11
       words: 3044
      flesch: 37
     summary: The economic impact of the COVID-19 pandemic on radiology practices Guidance and best practices for reestablishment of non-emergent care in nuclear cardiology laboratories during the coronavirus disease 2019 (COVID-19) pandemic: an information statement from ASNC, IAEA, and SNMMI Long-term prognostic value of coronary artery calcium scanning, coronary computed tomographic angiography and stress myocardial perfusion imaging in patients with suspected coronary artery disease Reperfusion delay in patients with high-risk ST-segment elevation myocardial infarction: every minute counts, much more than suspected Available from the official source of knowledge of the rules in force in Italy Population trends in rates of percutaneous coronary revascularization for acute coronary syndromes associated with the COVID-19 outbreak A new relational database including clinical data and myocardial perfusion imaging findings in coronary artery disease ACC/AHA 2002 guideline update for exercise testing: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1997 Exercise Testing Guidelines) EANM procedural guidelines for radionuclide myocardial perfusion imaging with SPECT and SPECT/CT: 2015 revision Quantification of myocardial perfusion reserve by CZT-SPECT: a head to head comparison with 82Rubidium PET imaging Exercise standards for testing and training: a scientific statement from the A novel high sensitivity rapid acquisition single photon cardiac imaging camera Head-to-head comparison of diagnostic accuracy of stress-only myocardial perfusion imaging with conventional and cadmium-zinc telluride single-photon emission computed tomography in women with suspected coronary artery disease A new algorithm for the quantitation of myocardial perfusion SPECT. For stress imaging studies, recordings were obtained by cadmiumzinc telluride (CZT)-SPECT (D-SPECT, Spectrum Dynamics, Caesarea, Israel) system using 9 pixilated CZT crystal detector columns mounted vertically spanning a 90°geometry [14] .
    keywords: covid-19; imaging; mpi; pandemic; patients; spect; stress; years
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        item: #1691 of 7819
          id: cord-270519-orh8fd1c
      author: Oliveira, A. C. S. d.
       title: Bayesian modeling of COVID-19 cases with a correction to account for under-reported cases
        date: 2020-05-25
       words: 4265
      flesch: 50
     summary: key: cord-270519-orh8fd1c authors: Oliveira, A. C. S. d.; Morita, L. H. M.; da Silva, E. B.; Granzotto, D. C. T.; Zardo, L. A. R.; Fontes, C. J. F. title: Bayesian modeling of COVID-19 cases with a correction to account for under-reported cases date: 2020-05-25 journal: nan DOI: 10.1101/2020.05.24.20112029 sha: doc_id: 270519 cord_uid: orh8fd1c The novel of COVID-19 disease started in late 2019 making the worldwide governments came across a high number of critical and death cases, beyond constant fear of the collapse in their health systems. To address these issues, we introduce a Bayesian approach to the SIR model with correction for under-reporting in the analysis of COVID-19 cases in Brazil.
    keywords: brazil; cases; covid-19; disease; license; medrxiv; model; preprint; rate; reporting
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        item: #1692 of 7819
          id: cord-270525-nmebqrb1
      author: Núñez-Velasco, Santiago
       title: Response to SARS-CoV-2 Pandemic in a Non-COVID-19 Designated Latin-American Neurosurgery Department
        date: 2020-05-11
       words: 2666
      flesch: 49
     summary: To correctly use this algorithm, we have defined a screening questionnaire ( Table 1 ) that includes the epidemiological, radiological, serum, and clinical criteria commonly described in COVID-19 patients and that are readily available in our hospital this questionnaire allows us to classify patients at high and low risk of developing COVID-19; this form must be completed by the team of on-call neurosurgery residents and reported to the attendings team on duty for verification. We classified neurosurgical patients into 4 groups depending on whether their condition demands care in 0-6 hours, 6-48 hours, 48 hours to 14 days, and >14 days.
    keywords: care; case; covid-19; department; patients; risk
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        item: #1693 of 7819
          id: cord-270528-3rsv3jlh
      author: Yazdanpanah, Fereshteh
       title: The immune system and COVID-19: Friend or foe?
        date: 2020-06-02
       words: 3138
      flesch: 36
     summary: Another noteworthy point is the increased level of enzymes in the liver, heart, and kidneys in COVID-19 patients with pneumonia, which is consistent with the tissue expression profile of the ACE2 receptor (10) ; this could also explain the occurrence of multi-organ failure in some patients (11). Overall, general lymphopenia is seen in COVID-19 patients, especially in severe cases (27, 28) .
    keywords: cells; coronavirus; cov-2; covid-19; disease; inflammatory; patients; sars
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        item: #1694 of 7819
          id: cord-270530-abiuiiff
      author: Fan, D.-P.
       title: Inf-Net: Automatic COVID-19 Lung Infection Segmentation from CT Scans
        date: 2020-04-27
       words: 6155
      flesch: 48
     summary: Although this is the first open-access COVID-19 dataset for lung infection segmentation, it suffers from a small sample size, i.e., only 100 labeled images are available. As can be observed, CT images are first fed to two convolutional layers to extract high-resolution, semantically weak (i.e., low-level) features.
    keywords: covid-19; deep; edge; features; images; inf; infection; learning; lung; model; net; segmentation
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        item: #1695 of 7819
          id: cord-270591-0szbkhiz
      author: Shi, Chen
       title: Comprehensive Landscape of Heparin Therapy for COVID-19
        date: 2020-10-22
       words: 6217
      flesch: 30
     summary: This review discusses the pharmacological mechanisms of heparin regarding its anticoagulant, anti-inflammatory and direct antiviral activities, providing current evidence concerning the effectiveness and safety of heparin therapy for this major public health emergency. On the basis of these critical functions of heparin, we illustrate both the preclinical and clinical evidence that heparin therapy has multiple effects for COVID-19.
    keywords: anticoagulant; binding; coronavirus; cov-2; covid-19; effects; et al; heparin; infection; low; patients; sars; sulfate; therapy
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        item: #1696 of 7819
          id: cord-270611-4hfn12hh
      author: Grossi, Enzo
       title: Guidelines for the Perplexed: How to Maximize Colonoscopy Efficiency During the COVID-19 Pandemic
        date: 2020-10-01
       words: 980
      flesch: 28
     summary: Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional multicenter study Digestive symptoms in COVID-19 patients with mild disease severity: clinical presentation, stool viral RNA testing, and outcomes Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis Practice of endoscopy during COVID-19 pandemic: position statements of the Asian Pacific Society for Digestive Endoscopy (APSDE-COVID statements) Endoscopy activity and COVID-19: BSG and JAG guidance Gastroenterology Professional Society Guidance on Endoscopic Procedures during the COVID-19 Pandemic 2020 A proposal for the return to routine endoscopy during the COVID-19 pandemic Burden and cost of gastrointestinal, liver, and pancreatic diseases in the United States: update Effect of diagnostic delay on survival in patients with colorectal cancer: a retrospective cohort study Adoption of multi-society guidelines facilitates value-based reduction in screening and surveillance colonoscopy volume during COVID-19 pandemic European Centre for Disease Prevention and Control.
    keywords: covid-19; guidelines; pandemic
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        item: #1697 of 7819
          id: cord-270614-4q7itegc
      author: Bisaillon, Laura
       title: Clever COVID-19, Clever Citizens-98: Critical and Creative Reflections from Tehran, Toronto, and Sydney
        date: 2020-08-25
       words: 2912
      flesch: 54
     summary: We argue that reflexive comparative analysis bridging social and visual analysis, anchored in embodied conditions of such people, offers a way to learn from responses to COVID-19 while also being an exercise in ethical research practice. We argue that reflexive comparative analysis bridging social and visual analysis, anchored in embodied conditions of such people, offers a way to learn from responses to COVID-19 while also being an exercise in ethical research practice.
    keywords: covid-19; iran; learning; nowruz; people; state; time
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        item: #1698 of 7819
          id: cord-270628-jtj30v0r
      author: Alharthy, Abdulrahman
       title: Prospective Longitudinal Evaluation of Point‐of‐Care Lung Ultrasound in Critically Ill Patients With Severe COVID‐19 Pneumonia
        date: 2020-08-14
       words: 4261
      flesch: 41
     summary: Is there a role for lung ultrasound during the COVID-19 pandemic? Proposal for international standardization of the use of lung ultrasound for COVID-19 patients; a simple, quantitative, reproducible method Point-of-care lung ultrasound in patients with COVID-19: a narrative review It's not over until it's over: the chameleonic behavior of COVID-19 over a six-day period COVID-19 outbreak: less stethoscope, more ultrasound Extension of coronavirus disease 2019 (COVID-19) on chest CT and implications for chest radiograph interpretation Relevance of lung ultrasound in the diagnosis of acute respiratory failure Bedside ultrasound assessment of positive end-expiratory pressureinduced lung recruitment Training for lung ultrasound score measurement in critically ill patients Ultrasound of the lungs more than a room with a view Ultrasonography for the assessment of lung recruitment maneuvers Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress Inter-rater reliability of quantifying pleural B-lines using multiple counting methods Diagnostic accuracy of chest radiograph, and when concomitantly studied lung ultrasound, in critically ill patients with respiratory symptoms: a systematic review and meta-analysis Lung ultrasound in the diagnosis and follow-up of community-acquired pneumonia: a prospective, multicenter, diagnostic accuracy study Clinical and computed tomographic imaging features of novel coronavirus pneumonia caused by SARS-CoV-2 Chest CT for typical 2019-nCoV pneumonia: relationship to negative RT-PCR testing Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT Clinical and high-resolution CT features of the COVID-19 infection: comparison of the initial and follow-up changes Proposal of a low-dose, long-pitch, dual-source chest CT protocol on third-generation dual-source CT using a tin filter for spectral shaping at 100 kVp for coronavirus disease 2019 (COVID-19) patients: a feasibility study Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding China Medical Treatment Expert Group for COVID-19. World Federation for Ultrasound in Medicine and Biology position statement: how to perform a safe ultrasound examination and clean equipment in the context of COVID-19 Lower-extremity Doppler for deep venous thrombosis: can emergency physicians be accurate and fast? Accuracy of ultrasonography performed by critical care physicians for the diagnosis of DVT Incidence of thrombotic complications in critically ill ICU patients with COVID-19 ISTH interim guidance on recognition and management of coagulopathy in COVID-19 Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Autopsy findings and venous thromboembolism in patients with COVID-19 Post-mortem examination of COVID-19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction Severe pulmonary embolism in COVID-19 patients: a call for increased awareness Thrombotic and hemorrhagic events in critically ill COVID-19 patients: a French monocenter retrospective study Acute kidney injury in the intensive care unit according to RIFLE Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72,314 cases from the Chinese Center for Disease Control and Prevention A trial of lopinavir-ritonavir in adults hospitalized with Severe COVID-19 Sonographic signs and patterns of COVID-19 pneumonia.
    keywords: admission; coronavirus; covid-19; findings; icu; lung; patients; pneumonia; pocus; study; ultrasound
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        item: #1699 of 7819
          id: cord-270654-cz2y6ta9
      author: Deftereos, Spyridon G.
       title: The Greek study in the effects of colchicine in COvid-19 complications prevention (GRECCO-19 study): Rationale and study design
        date: 2020-04-03
       words: 2116
      flesch: 30
     summary: Among its potential mechanisms of action is the non-selective inhibition of NLRP3 inflammasome which is thought to be a major pathophysiologic component in the clinical course of patients with COVID-19. Among its potential mechanisms of action is the non-selective inhibition of NLRP3 inflammasome which is thought to be a major pathophysiologic component in the clinical course of patients with COVID-19.
    keywords: acute; colchicine; covid-19; inflammasome; nlrp3; patients; study
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        item: #1700 of 7819
          id: cord-270669-hng8ivz2
      author: Li, R.
       title: Perceived vulnerability to COVID-19 infection from event attendance: Results from Louisiana, USA, two weeks preceding the national emergency declaration
        date: 2020-04-06
       words: 3825
      flesch: 45
     summary: All participants signed informed consent forms after nationally (line graph, right axis) and in Louisiana (bar graph, left axis) for the study period, while Figure 2 traces the daily averages among study participants for the two COVID-19 1 6 8 questions, while highlighting key events in the evolution of COVID-19 timeline for Louisiana. of risk perception to self-prophylaxis measures, such as social distancing, which slows 3 1 7 community spread.
    keywords: covid-19; license; march; medrxiv; participants; preprint; study
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        item: #1701 of 7819
          id: cord-270721-81axdn0g
      author: Allam, Zaheer
       title: The Emergence of Voluntary Citizen Networks to Circumvent Urban Health Data Sharing Restrictions During Pandemics
        date: 2020-07-24
       words: 5165
      flesch: 39
     summary: When all these challenges are compounded, as noted by Waithira et al. (2019) , it becomes relatively hard to convince people to freely share their data, as already the levels of mistrust on agencies handling data are high and thus are seen to create psychological barriers to data sharing. Such data have also become very popular for target marketing and those with capacity to collect gain financially by sharing insights with marketing institutions.
    keywords: allam; case; coronavirus; covid-19; data; health; share; sharing; technologies; virus
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        item: #1702 of 7819
          id: cord-270723-cjfglili
      author: Fteiha, Bashar
       title: QTc prolongation among hydroxychloroquine sulfate‐treated COVID‐19 patients: An observational study
        date: 2020-10-15
       words: 3324
      flesch: 46
     summary: An open-label nonrandomized (nowadays controversial) trial also showed that HCQ treatment was associated with a significant reduction in viral shedding, an effect reportedly accentuated by concomitant treatment with azithromycin in six patients 4 . Data collection and variables: All relevant demographic, clinical and laboratory data (including additional medications which could potentially prolong QTc interval, prescribed throughout hospitalization and overlapped with HCQ treatment) were collected from the electronic medical record (EMR).
    keywords: covid-19; hcq; interval; patients; prolongation; qtc; treatment
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        item: #1703 of 7819
          id: cord-270740-3su8pc3f
      author: Sultan, Sherif
       title: COVID-19 Cytokine Storm and Novel Truth
        date: 2020-05-22
       words: 2383
      flesch: 50
     summary: Recurrent admission for post-hypoxic leukoencephalopathy strengthens the findings of the Italians, Spanish and Americans(4) that COVID-19 patients are suffering from metabolic hypoxia due to blood capacity failure. In COVID-19 patients, unlike with CO poisoning in which eventually the CO can break off, the affected hemoglobin is permanently stripped of its ability to carry oxygen.
    keywords: blood; coronavirus; covid-19; novel; oxygen; patients; storm
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        item: #1704 of 7819
          id: cord-270742-kzo879gu
      author: Naeem, Syed
       title: Successful recovery from COVID‐19 in three kidney transplant recipients who received convalescent plasma therapy
        date: 2020-08-19
       words: 2708
      flesch: 40
     summary: Emerging infectious diseases Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Drug treatment options for the 2019-new coronavirus (2019-nCoV) Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience Use of convalescent plasma therapy in SARS patients in Hong Kong Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection Accepted Article Since MERS, SARS-CoV-1, and SARS-CoV-2 share many similar virulence and clinical characteristics 9 , CP therapy may be a potentially efficacious treatment for COVID-19 patients 10 .
    keywords: ccp; covid-19; disease; patients; sars; therapy
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        item: #1705 of 7819
          id: cord-270781-f9nra823
      author: Gulia, Ashish
       title: Sarcoma Care Practice in India During COVID Pandemic: A Nationwide Survey
        date: 2020-07-31
       words: 3357
      flesch: 50
     summary: This, coupled with delayed presentation of patients (both from fear of going out and from a lack of means of travel during the lockdown) is likely to lead to a delayed diagnosis and stage migration of a large number of cancer patients [3] . Ministry of Health and Family Welfare, Govt of India recommends full complement of PPE use by HCWs for (a) Intensive Care Unit (ICU)/critical care patients, (b) emergency severely ill patients of Severe Acute Respiratory Infection (SARI) (c) during transport of SARI patients (d) sample collection, transport and testing and (e) autopsy
    keywords: covid-19; fig; management; pandemic; patients; respondents; survey
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        item: #1706 of 7819
          id: cord-270784-cmhtpxz7
      author: Thorakkattil, Shabeer A.
       title: Structural and operational redesigning of patient-centered ambulatory care pharmacy services and its effectiveness during the COVID-19 pandemic
        date: 2020-06-23
       words: 2595
      flesch: 36
     summary: 20 Person-and patient-centered interventions applied within JHAH ambulatory care pharmacy services due to COVID-19 pandemic include the following: (I) General pharmacy infection control and prevention measures, (II) access to medication management care measures, (III) business continuity and staffing measures, and (IV) medication automation-related measures. • On April 20, 2020, JHAH ambulatory care pharmacy services launched a pilot home delivery process to cater to cancer patients or patients aged above 60 years for due medication refills via a third-party courier provider.
    keywords: care; covid-19; jhah; medication; pandemic; patient; pharmacy; services
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        item: #1707 of 7819
          id: cord-270799-2pmpspuj
      author: Zayet, Souheil
       title: Clinical features of COVID-19 and influenza: A comparative study on Nord Franche-Comte cluster
        date: 2020-06-16
       words: 2852
      flesch: 48
     summary: In two groups patients without fever or a feeling of 136 fever were scarce: 4 patients in COVID-19 group and 1 patient in influenza group (p=0,386). However, 137 fever ≥38°C was significantly higher in influenza group than COVID-19 group (93% vs 76% 138 respectively, p=0.042) but the mean highest temperature was not significantly different (39°C vs 139 38.7°C respectively; p=0.064).
    keywords: covid-19; days; group; influenza; patients; symptoms
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        item: #1708 of 7819
          id: cord-270828-h9tgkboe
      author: Huang, V. S.
       title: Social distancing across vulnerability, race, politics, and employment: How different Americans changed behaviors before and after major COVID-19 policy announcements
        date: 2020-06-08
       words: 8771
      flesch: 38
     summary: We did this by computing social distancing for individual employment sectors at the national level, by weighting county social distancing by each sector's employment level (i.e., number of jobs) in the county. key: cord-270828-h9tgkboe authors: Huang, V. S.; Sutermaster, S.; Caplan, Y.; Kemp, H.; Schmutz, D.; Sgaier, S. K. title: Social distancing across vulnerability, race, politics, and employment: How different Americans changed behaviors before and after major COVID-19 policy announcements date: 2020-06-08 journal: nan DOI: 10.1101/2020.06.04.20119131 sha: doc_id: 270828 cord_uid: h9tgkboe Background: As states reopen in May 2020, the United States is still trying to curb the spread of the COVID-19 pandemic.
    keywords: counties; covid-19; data; distancing; license; medrxiv; pandemic; preprint; social; time; vulnerability; week; weekdays; weekends
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        item: #1709 of 7819
          id: cord-270858-ozvdz9ew
      author: Altmann, Daniel M
       title: What policy makers need to know about COVID-19 protective immunity
        date: 2020-04-27
       words: 1564
      flesch: 41
     summary: 13 Some of the uncertainty about COVID-19 protective immunity could be addressed by monitoring the frequency of reinfection with SARS-CoV-2. Specific T-lymphocyte immunity against Middle East respiratory syndrome coronavirus, however, can be detectable for 4 years, considerably longer than antibody responses.
    keywords: antibody; covid-19; immunity; sars; virus
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        item: #1710 of 7819
          id: cord-270866-olc5r2yx
      author: Mallet, Jasmina
       title: Addictions in the COVID-19 era: Current evidence, future perspectives a comprehensive review
        date: 2020-08-12
       words: 6846
      flesch: 43
     summary: Most experts fear an on-going « Opioid Crisis » that could endanger and further marginalize an already at-risk population (Alexander et al., 2020; Becker and Fiellin, 2020; Jenkins et al., 2020; Sun et al., 2020; Wilson et al., 2020) . Persons receiving take-home methadone could be co-prescribed naloxone, an opioid reversal agent that may mitigate the risks of fatal overdose among those at high risk (Alexander et al., 2020) .
    keywords: alcohol; covid-19; et al; increase; lockdown; opioid; pandemic; review; risk; smoking; study; tobacco; use
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        item: #1711 of 7819
          id: cord-270868-4s3q2i6v
      author: Collins, Lauren F.
       title: Clinical characteristics, comorbidities and outcomes among persons with HIV hospitalized with coronavirus disease 2019 in Atlanta, Georgia
        date: 2020-10-01
       words: 2185
      flesch: 42
     summary: This report supports dedicated larger study of COVID-19 among PWH to determine the role of age, comorbidities, immunocompetency, HIV control and antiretroviral agents in mediating COVID-19 presentation and its sequelae. COVID-19): people who are at higher risk Challenges of reaching 90-90-90 in the Southern United States Comorbidities in persons with HIV: the lingering challenge The prevalence and burden of non-AIDS comorbidities among women living with or at-risk for HIV infection in the United States Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Characteristics of hospitalized adults with COVID-19 in an integrated healthcare system in California COVID-19 in HIV Investigators. It is possible that the premature onset of multimorbidity among PWH considerably impacts SARS-CoV-2 infection and illness severity, distinct from HIV infection or its associated immunosuppression.
    keywords: comorbidities; covid-19; hiv; patients; pwh
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        item: #1712 of 7819
          id: cord-270885-wkczsrgu
      author: O'Donoghue, Cathal
       title: Modelling the Distributional impact of the Covid‐19 Crisis(1)
        date: 2020-06-17
       words: 4370
      flesch: 45
     summary: The Household Budget Survey reports both the distribution of childcare costs per family type and by disposable income distribution. In managing income distribution impacts (and associated fiscal costs) it is valuable to be able to assess the effects of different wage and unemployment support policies given the most up-to-date information on the labour market.
    keywords: costs; crisis; data; distribution; household; income; market; work
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        item: #1713 of 7819
          id: cord-270896-uw59kk4y
      author: Benson, Nicole M
       title: COVID-19 testing and patients in mental health facilities
        date: 2020-05-11
       words: 996
      flesch: 31
     summary: In addition to testing patients, prevention should centre around providing safe conditions for patients and staff. Preliminary findings of the subcommittee's coronavirus antibody testing investigation Nursing homes are ground zero for COVID-19 pandemic Why psychiatric wards are uniquely vulnerable to the coronavirus Incorporating test characteristics into SARS-CoV-2 testing policy-sense and sensitivity Study raises questions about false negatives from quick COVID-19 test There are not enough COVID-19 tests.
    keywords: covid-19; facilities; patients
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        item: #1714 of 7819
          id: cord-270897-fywmv7jg
      author: Pattanakuhar, Sintip
       title: A Patient with Acute Cervical Cord Injury and COVID-19: A First Case Report
        date: 2020-06-01
       words: 1363
      flesch: 47
     summary: Rehabilitation personnel who take care of acute SCI patients with COVID-19 should consider the effect of SCI on the course of COVID-19, the effect of COVID-19 and its treatments on the course of SCI, and risks of SAR-CoV2 transmission between patients and rehabilitation staff, to continue providing safe and effective rehabilitation programs. Therefore, rehabilitation personnel who take care of acute SCI patients with COVID-19 should always consider the effect of SCI on the course of COVID-19, the effect of COVID-19 and its treatment on the course of SCI, and risks of SAR-CoV2 transmission between patients and rehabilitation staffs, to continue providing safe and effective rehabilitation programs.
    keywords: acute; covid-19; patient; sci
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        item: #1715 of 7819
          id: cord-270922-7z0n78ja
      author: Lee, You Hyun
       title: Characteristics of Ocular Manifestations of Patients with Coronavirus Disease 2019 in Daegu Province, Korea
        date: 2020-09-01
       words: 2347
      flesch: 42
     summary: Positive upper respiratory infection symptoms and lower creatine phosphokinase were determined to be related to ocular symptoms in COVID-19 patients. One previous study reported that 31.6% of COVID-19 patients showed that ocular abnormalities and higher procalcitonin level, white blood cell count, neutrophil count, C-reactive protein level, and lactate dehydrogenase level have a correlation to ocular symptoms.
    keywords: covid-19; episode; group; patients; symptoms
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        item: #1716 of 7819
          id: cord-270933-ecmg8kti
      author: Ali, Ashaq
       title: COVID-19: Clinical aspects and therapeutics responses
        date: 2020-07-03
       words: 1657
      flesch: 43
     summary: We found the new combination is very effective against patients with mild symptoms and asymptomatic patients. The major ingredients of LH consisted of Lonicera japonica, Forsythia suspensa, Isatis indigotica , Ephedra sinica, combination with the antiviral drug for COVID-19 in asymptomatic patients or patients with mild symptoms.
    keywords: covid-19; patients; symptoms
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        item: #1717 of 7819
          id: cord-270934-vzsdvrwo
      author: Raza, Azra
       title: Rewriting the rules for care of MDS and AML patients in the time of COVID-19
        date: 2020-04-20
       words: 2007
      flesch: 41
     summary: key: cord-270934-vzsdvrwo authors: Raza, Azra; Assal, Amer; Ali, Abdullah M.; Jurcic, Joseph G. title: Rewriting the rules for care of MDS and AML patients in the time of COVID-19 date: 2020-04-20 journal: Leuk Res Rep DOI: 10.1016/j.lrr.2020.100201 sha: doc_id: 270934 cord_uid: vzsdvrwo This communication summarizes the immediate changes in how we care for our MDS and AML patients during the pandemic.
    keywords: aml; care; covid-19; mds; pandemic; patients
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        item: #1718 of 7819
          id: cord-270935-t9pym9k0
      author: Dumyati, Ghinwa
       title: Does Universal Testing for COVID-19 Work for Everyone?
        date: 2020-08-15
       words: 2683
      flesch: 45
     summary: We review the tests available to diagnose COVID-19 infections, the implications of universal testing for nursing home staff and residents, interpretation of test results, issues around repeat testing, and incorporation of test results as part of a long-term response to the COVID-19 pandemic. Efforts by states to relax stay-at-home orders, reopen businesses, and even 298 encourage tourism 38 contribute to increased spread of SARS-CoV-2 in the community which in 299 turn means increased risk for nursing home staff to acquire and transmit the virus to their 300 residents.
    keywords: covid-19; nursing; residents; results; staff; testing; tests
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        item: #1719 of 7819
          id: cord-270951-6nq3jwgr
      author: Amerio, Paolo
       title: COVID‐19 and psoriasis: Should we fear for patients treated with biologics?
        date: 2020-05-05
       words: 2259
      flesch: 44
     summary: The importance of the role of massive release of proinflammatory cytokines (cytokine storm) is underlined by the fact that there is a significant difference in the concentration of serum of IFN-γ, IL-1, IL-6, IL-12, and TGFβ and of chemokines such as CCL2, CXCL10, CXCL9, and IL-8 between severe disease SARS patients compared to uncomplicated SARS patients. Cytokines such as IL-1, IL-6 and IL-12, and chemokines such as IL-8, CCL2 and CXCL10 were elevated in SARS patients 6 and diminished in patients that recovered, accompanied by a robust anti-virus antibody response.
    keywords: covid-19; disease; patients; psoriasis; sars; treatment
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        item: #1720 of 7819
          id: cord-270970-9gtnsyts
      author: Wolf, Michael S.
       title: Awareness, Attitudes, and Actions Related to COVID-19 Among Adults With Chronic Conditions at the Onset of the U.S. Outbreak: A Cross-sectional Survey
        date: 2020-04-09
       words: 4497
      flesch: 45
     summary: Health literacy has emerged over the past 3 decades as one of the strongest psychosocial determinants of health, and it has also been shown to explain a range of health disparities by age, race/ ethnicity, and socioeconomic status (6) . We focused on the role of health literacy and other psychosocial health determinants in understanding risks for COVID-19 and the initiation of preventive behaviors. health services, are sponsored by the National Institutes of Health, and are taking place among 7 primary care sites (5 academic internal medicine clinics and 2 federally qualified health centers) across the greater Chicago area ( Table 1) .
    keywords: adults; coronavirus; covid-19; health; literacy; outbreak; participants; study; survey
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        item: #1721 of 7819
          id: cord-270983-2m38duq4
      author: Schuivens, Puck M.E.
       title: Impact of the COVID-19 lock down strategy on vascular surgery practice: more major amputations than usual
        date: 2020-08-04
       words: 831
      flesch: 50
     summary: Values are numbers (percentages) unless stated otherwise 5 *Chi-square test with Bonferroni correction 6 † p-value <.05 7 ‡ Statistically significant difference between observed number of patients in 2020 and 2019 8 § The observed number of patients in 2020 differs significantly from 2019 and 2018 9 J o u r n a l P r e -p r o o f ‡ statistically significant difference between observed numbers 2020 and 2018 13 The epidemiology and 210 clinical information about COVID-19
    keywords: covid-19; lockdown; patients
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        item: #1722 of 7819
          id: cord-270987-7vm6heh1
      author: Al-Awadhi, Abdullah M.
       title: Death and contagious infectious diseases: Impact of the COVID-19 virus on stock market returns
        date: 2020-04-08
       words: 1996
      flesch: 54
     summary: Stock market returns respond to major events. Stock market returns may also respond to epidemic diseases, for example, Severe Acute Respiratory Syndrome (SARS) outbreak (Chen et al., 2007; Chen et al., 2009) , and Ebola Virus Disease (EVD) outbreak (Ichev & Marinč, 2018) .
    keywords: cases; covid-19; growth; market; stock
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        item: #1723 of 7819
          id: cord-271032-imc6woht
      author: Schulte-Schrepping, Jonas
       title: Severe COVID-19 is marked by a dysregulated myeloid cell compartment
        date: 2020-08-05
       words: 9745
      flesch: 42
     summary: Interestingly, immature cell clusters in severe COVID-19 showed signs of recent activation 390 like upregulation of CD64 (Mortaz et al., 2018) , RANK and RANKL (Riegel et al., 2012) , as 391 well as reduced CD62L expression (Mortaz et al., 2018) . Plotting cell cluster-specific surface marker expression onto 384 the UMAPs (Fig. 6C ) as well as statistical analyses of cell cluster distribution and surface 385 marker expression among different patient groups supported these observations (Fig. 386 6D+E) .
    keywords: analysis; cell; cluster; cohort; covid-19; data; disease; expression; fig; genes; hla; marker; monocytes; neutrophils; patients; pbmc; samples; scrna; seq; table
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        item: #1724 of 7819
          id: cord-271042-0ilj86y9
      author: Bonanad, Clara
       title: Coronavirus: la emergencia geriátrica de 2020. Documento conjunto de la Sección de Cardiología Geriátrica de la Sociedad Española de Cardiología y la Sociedad Española de Geriatría y Gerontología
        date: 2020-04-03
       words: 5732
      flesch: 38
     summary: Por otro lado, además de existir una asociación entre el antecedente de ECV y la presencia y la gravedad de la COVID-19, la propia infección se asocia con manifestaciones cardiovasculares. Se desconocen los mecanismos fisiopatológicos específicos que expliquen esta asociación entre ECV y la frecuencia y la gravedad de la infección por COVID-19, pero la edad puede ser uno de los factores implicados más allá de la mera asociación epidemiológica.
    keywords: 2020; avanzada; años; casos; como; con; coronavirus; covid-19; datos; de la; debe; del; ecv; edad; enfermedad; entre; esta; este; infección; las; los; mayor; mayores; mortalidad; más; pacientes; para; población; por; puede; que; riesgo; situación; sobre; una
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        item: #1725 of 7819
          id: cord-271048-tq1sk01g
      author: Ellis, R.
       title: Operating during the COVID-19 pandemic: How to reduce medical error
        date: 2020-04-13
       words: 1683
      flesch: 49
     summary: Webinars on Covid19 Leading article: What can we do to improve individual and team situational awareness to benefit patient safety? Impact of hydration and nutrition on personal performance in the clinical workplace Sleep: its importance and theeffects of deprivation on surgeons and other healthcare professionals The impact and effect of emotional resilience on performance: an overview for surgeons and other healthcare professionals Challenging hierarchy in healthcare teams -ways to flatten gradients to improve teamwork and patient care Full PPE can be distracting when first worn, therefore where possible operate with other senior team members to reduce the risk of error.
    keywords: care; covid-19; members; operating; patients
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        item: #1726 of 7819
          id: cord-271062-ev2efm10
      author: Fransawy Alkomos, Mina
       title: COVID-19 Presenting as Acute Bilateral Submassive Pulmonary Embolism in a Young Healthy Female
        date: 2020-07-19
       words: 1240
      flesch: 41
     summary: 2020 Clinical characteristics of coronavirus disease 2019 in China Clinical, laboratory, roentgenographic, and electrocardiographic findings in patients with acute pulmonary embolism and no pre-existing cardiac or pulmonary disease Prognostic value of the ECG on admission in patients with acute major pulmonary embolism Findings from 12-lead electrocardiography that predict circulatory shock from pulmonary embolism: systematic review and meta-analysis Acute pulmonary embolism and COVID-19 pneumonia: a random association COVID-19 pneumonia with hemoptysis: Acute segmental pulmonary emboli associated with novel coronavirus infection COVID-19 complicated by acute pulmonary embolism Prognostic value of echocardiography and spiral computed tomography in patients with pulmonary embolism Since EKG finding of S(I) Q(III) T(III) pattern and right ventricular strain, and ECHO finding of right ventricular dysfunction are well described in PE but not in COVID-19, these bedside diagnostic tools can help identify COVID-19 patients with underlining PEs.
    keywords: covid-19; embolism; patients
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        item: #1727 of 7819
          id: cord-271089-xzckxnv8
      author: Lifshits, M.
       title: COVID-19 mortality rate in Russia: forecasts and reality evaluation
        date: 2020-09-25
       words: 6164
      flesch: 53
     summary: key: cord-271089-xzckxnv8 authors: Lifshits, M.; Neklyudova, N. title: COVID-19 mortality rate in Russia: forecasts and reality evaluation date: 2020-09-25 journal: nan DOI: 10.1101/2020.09.25.20201376 sha: doc_id: 271089 cord_uid: xzckxnv8 COVID-19 is an extremely dangerous disease that not only spreads quickly, but is also characterized by a high mortality rate. The aim of the study is to analyze the factors affecting COVID-19 mortality rate in various countries, to predict direct and indirect victims of the pandemic in the Russian Federation, and to estimate additional mortality during the pandemic based on the demographic data.
    keywords: april; covid-19; data; deaths; infected; mortality; number; regions; russia
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        item: #1728 of 7819
          id: cord-271142-ncmr955j
      author: Brandariz-Nuñez, D.
       title: Interacciones medicamentosas potenciales en pacientes COVID 19 en tratamiento con lopinavir/ritonavir
        date: 2020-07-09
       words: 3077
      flesch: 38
     summary: Se incluyeron 361 pacientes con una media de edad de 62,77 ± 14,64 años, donde Se registró y analizó la prevalencia de interacciones potenciales en pacientes COVID19
    keywords: con; covid; drug; fármacos; interacciones; las; los; lpv; pacientes; por; potenciales; que; riesgo; tratamiento
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        item: #1729 of 7819
          id: cord-271168-a9sf8f4p
      author: Montaner, Joan
       title: Break in the Stroke Chain of Survival Due to COVID-19
        date: 2020-06-08
       words: 3976
      flesch: 48
     summary: We wondered how the measures aimed at COVID-19 are changing the way stroke patients are treated and observed that the growing pandemic had produced a reduction in the number of acute stroke patients that come into our healthcare system. In conclusion, huge collateral damage to acute stroke patients is occurring during the COVID-19 pandemic.
    keywords: acute; cases; covid-19; hospitals; number; outbreak; patients; stroke
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        item: #1730 of 7819
          id: cord-271174-886xc1n3
      author: Lipworth, Brian
       title: Weathering the Cytokine Storm in Susceptible Patients with Severe SARS-CoV-2 Infection
        date: 2020-04-18
       words: 2347
      flesch: 27
     summary: ACE-2 expression in the small airway epithelia of smokers and COPD patients: Implications for COVID-19 A trial of lopinavir-ritonavir in adults hospitalized with severe COVID-19 Compassionate use of remdesivir for patients with severe COVID-19 Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro Selective regulation of cytokine secretion by hydroxychloroquine: inhibition of interleukin 1 alpha (IL-1-alpha) and IL-6 in human monocytes and T cells TMPRSS2: a potential target for treatment of influenza virus and coronavirus infections Oncedaily single-inhaler triple versus dual therapy in patients with COPD Current appraisal of single inhaler triple therapy in COPD Corticosteroid suppression of antiviral immunity increases bacterial loads and mucus production in COPD exacerbations Inhaled corticosteroid suppression of cathelicidin drives dysbiosis and bacterial infection in chronic obstructive pulmonary disease Precision medicine urgency: the case of inhaled corticosteroids in COPD Pneumonia risk in asthma patients using inhaled corticosteroids: a quasi-cohort study The inhaled corticosteroid ciclesonide blocks coronavirus RNA replication by targeting viral NSP15 Acute lung injury induces cardiovascular dysfunction: effects of IL-6 and budesonide/formoterol Differences between asthmatics and nonasthmatics hospitalised with influenza A infection Blood eosinophil guided prednisolone therapy for exacerbations of COPD: a further analysis Glucocorticosteroids enhance replication of respiratory viruses: effect of adjuvant interferon COVID-19: consider cytokine storm syndromes and immunosuppression Level of IL-6 predicts respiratory failure in hospitalized symptomatic COVID-19 patients Effective treatment of severe COVID-19 patients with tocilizumab B. Lipworth had the idea and is responsible for the overall content as guarantor. Having said that compassionate use of iv remdesivir in 53 patients with severe COVID-19 infection resulted in 68% having improved oxygenation status and 18% mortality among those receiving invasive ventilation, albeit with no control arm for comparison.
    keywords: covid-19; hydroxychloroquine; il-6; infection; patients; risk; sars
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        item: #1731 of 7819
          id: cord-271186-82q22u6i
      author: Picichè, Marco
       title: Cardiac Involvment in SARS-CoV-2-Associated Inflammatory Syndromes
        date: 2020-08-05
       words: 1219
      flesch: 35
     summary: While Europe carefully reopened its borders to travelers after the incidence of new COVID-19 cases dramatically decreased during a lockdown, the virus continues to run rampant in the United States and Latin America. However, notwithstanding the existence of considerable observational data on the use of ECMO for influenza A (H1N1) and Middle East Respiratory Syndrome (MERS) coronavirus-related ARDS, the real utility of ECMO in adult COVID-19 patients with respiratory failure is uncertain and remains under investigation [15] .
    keywords: children; covid-19; inflammatory; syndrome
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        item: #1732 of 7819
          id: cord-271187-rlevoj41
      author: Vijh, Rohit
       title: Serological Survey following SARS-COV-2 Outbreaks at Long Term Care Facilities in Metro Vancouver, British Columbia: Implications for Outbreak Management and Infection Control Policies
        date: 2020-10-18
       words: 1511
      flesch: 23
     summary: key: cord-271187-rlevoj41 authors: Vijh, Rohit; Ghafari, Cher; Hayden, Althea; Schwandt, Michael; Sekirov, Inna; Morshed, Muhammad; Levett, Paul; Krajden, Mel; Boraston, Suni; Daly, Patricia; Lysyshyn, Mark; Harding, John; McLennan, Meghan; Chahil, Navdeep; Mak, Annie; McKee, Geoff title: Serological Survey following SARS-COV-2 Outbreaks at Long Term Care Facilities in Metro Vancouver, British Columbia: Implications for Outbreak Management and Infection Control Policies date: 2020-10-18 journal: Am J Infect Control DOI: 10.1016/j.ajic.2020.10.009 sha: doc_id: 271187 cord_uid: rlevoj41 A cross-sectional serological survey was carried out in two long term care facilities that experienced COVID-19 outbreaks in order to evaluate current clinical COVID-19 case definitions. A cross-sectional serological survey was carried out in two long term care facilities that experienced COVID-19 outbreaks in order to evaluate current clinical COVID-19 case definitions.
    keywords: case; covid-19; ltc; residents; symptoms
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        item: #1733 of 7819
          id: cord-271212-y8denvju
      author: Xu, Xia
       title: Analysis of inflammatory parameters and disease severity for 88 hospitalized COVID-19 patients in Wuhan, China
        date: 2020-07-25
       words: 3103
      flesch: 47
     summary: COVID-19 patients were diagnosed through the symptoms and computed tomography (CT) image combining the detection of 2019-nCoV RNA or the specific virus IgM and IgG antibody to COVID-19. The study population included 88 confirmed and hospitalized COVID-19 patients.
    keywords: china; clinical; coronavirus; covid-19; disease; patients; severity; study
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        item: #1734 of 7819
          id: cord-271220-sntawlnf
      author: Tadic, Marijana
       title: COVID‐19 and diabetes: Is there enough evidence?
        date: 2020-05-29
       words: 2434
      flesch: 33
     summary: In one of the largest study published (n = 1099) so far, diabetes was present in 7.4% of COVID-19 patients and it was significantly more prevalent in patients with severe form of disease and those who experienced primary outcome end point (admission to an intensive care unit, the use of mechanical ventilation, or death). The same group of authors in a larger group of COVID-19 patients (n = 1590) reported diabetes in 8.2%, and it was significantly more prevalent among COVID-19 patients with severe form than in patients with non-severe form of disease (34.6% vs 14.3%).
    keywords: covid-19; diabetes; disease; patients
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        item: #1735 of 7819
          id: cord-271221-aoc61qy5
      author: Markowitz, Kenneth
       title: Fever and other clinical indicators may fail to detect COVID-19 infected individuals
        date: 2020-09-22
       words: 678
      flesch: 44
     summary: Although commonly conducted in dental facilities, using body temperature measurements and a person's self-report of symptoms can fail to identify COVID-19 infected individuals. Since many dental procedures result in aerosols, COVID-19 infected patients pose an infection risk to staff and other patients even with infection control practices.
    keywords: covid-19; screening
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        item: #1736 of 7819
          id: cord-271235-rsewj2mv
      author: Morgul, Ebru
       title: COVID-19 pandemic and psychological fatigue in Turkey
        date: 2020-07-10
       words: 3663
      flesch: 38
     summary: Multivariate stepwise regression analysis indicated that level of education, avoiding going to crowded places, eye, nose and mouth organs are sensitive organs to the virus, keeping physical distance due to epidemic affect by COVID-19 virus, isolation and treatment of people reduce the spread of COVID-19 virus and 14-days period of time, COVID-19 is mainly transmitted through contact with the respiratory droplets of an infected person, occupational status, health education programme needed and antibody treatment variables were significantly associated with fatigue after adjusting for age, gender and income variables. Table 2 also reveals the attitude, behaviour and practices of subjects towards COVID-19 virus by fatigue.
    keywords: covid-19; et al; fatigue; health; pandemic; participants
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        item: #1737 of 7819
          id: cord-271262-xglhx928
      author: Ghia, Samit
       title: “ANESTHESIA STAT” TO INTUBATE A COVID-19 PATIENT: IMPLICATIONS FOR THE ANESTHESIOLOGIST
        date: 2020-05-15
       words: 3281
      flesch: 35
     summary: Opioids are an option in inducing COVID-19 patients; however, large fentanyl doses have been associated with post-induction hypotension, possibly due to sympathetic attenuation, which could be significantly pronounced and devastating in septic patients [12] . Although reducing exposure of medical personnel is of obvious importance, there has been a dearth of literature discussing clinical strategies during the induction and intubation of COVID-19 patients.
    keywords: airway; anesthesiologist; covid-19; exposure; induction; intubation; patients; room
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        item: #1738 of 7819
          id: cord-271295-24rn45rf
      author: Shoja, Esmail
       title: Covid-19 effects on the workload of Iranian healthcare workers
        date: 2020-11-02
       words: 3248
      flesch: 53
     summary: Moreover, health care workers feel chronic fear of infection due to this virus's contagious nature, unknown transmission modes, close contact with patients, and getting infection from their colleagues [6] . Health workers who encountered COVID- 19 patients, were subjected to more task load compared to those who had no contact with COVID- 19 patients at the workplace (p < 0.001).
    keywords: covid-19; health; nasa; patients; study; tlx
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        item: #1739 of 7819
          id: cord-271308-nypkr537
      author: Drexler, Richard
       title: Involvement of Medical Students During the Coronavirus Disease 2019 Pandemic: A Cross-Sectional Survey Study
        date: 2020-08-30
       words: 3555
      flesch: 47
     summary: key: cord-271308-nypkr537 authors: Drexler, Richard; Hambrecht, Jan M; Oldhafer, Karl J title: Involvement of Medical Students During the Coronavirus Disease 2019 Pandemic: A Cross-Sectional Survey Study date: 2020-08-30 journal: Cureus DOI: 10.7759/cureus.10147 sha: doc_id: 271308 cord_uid: nypkr537 Background: The coronavirus disease 2019 (COVID-19) pandemic affects the education of medical students around the world and countries have had differing responses in dealing with this dynamic situation. The role of medical students in fighting this pandemic is controversial and it is yet to be elucidated how they can best be of service.
    keywords: covid-19; pandemic; students; survey; work; year
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        item: #1740 of 7819
          id: cord-271337-2ioap802
      author: Tang, Xiao
       title: Comparison of Hospitalized Patients With ARDS Caused by COVID-19 and H1N1
        date: 2020-03-26
       words: 3652
      flesch: 46
     summary: There was a greater variety of antiviral therapies administered to COVID-19 patients than to H1N1 patients. SOFA score-adjusted mortality of H1N1 patients was significantly higher than that of COVID-19 patients, with a rate ratio of 2.009 (95% CI, 1.563-2.583; P < .001).
    keywords: ards; clinical; covid-19; h1n1; mortality; patients; study
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        item: #1741 of 7819
          id: cord-271362-qn5i6cdj
      author: Zheng, Lei
       title: Perceived Control Buffers the Effects of the COVID‐19 Pandemic on General Health and Life Satisfaction: The Mediating Role of Psychological Distance
        date: 2020-09-21
       words: 5591
      flesch: 37
     summary: This study found that perceived control could moderate the mediating effect of psychological distance, in which perceived control not only buffers the detrimental effects of regional pandemic severity on psychological distance, but also alleviates the negative impact of psychological distance from COVID-19 on perceived life satisfaction. This study aimed to examine the effects of COVID‐19 on life satisfaction and perceived general health and reveal the buffering effect of perceived control on coping with COVID‐19.
    keywords: control; distance; health; life; pandemic; satisfaction; severity
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        item: #1742 of 7819
          id: cord-271363-nsjn05q0
      author: Page, Matthew J.
       title: ‘One more time’: why replicating some syntheses of evidence relevant to COVID-19 makes sense
        date: 2020-05-25
       words: 2496
      flesch: 26
     summary: key: cord-271363-nsjn05q0 authors: Page, Matthew J.; Welch, Vivian A.; Haddaway, Neal R.; Karunananthan, Sathya; Maxwell, Lara J.; Tugwell, Peter title: ‘One more time’: why replicating some syntheses of evidence relevant to COVID-19 makes sense date: 2020-05-25 journal: J Clin Epidemiol DOI: 10.1016/j.jclinepi.2020.05.024 sha: doc_id: 271363 cord_uid: nsjn05q0 • Given the urgent need for credible answers to high-priority questions about the health and social impacts of COVID-19, many systematic reviewers seek to contribute their skills and expertise; • Rather than embarking on unnecessary, duplicate reviews, we encourage the evidence synthesis community to prioritise purposeful replication of systematic reviews of evidence relevant to COVID-19. Systematic reviews are required to address not only the aetiology, diagnosis, prognosis and treatment of symptoms of COVID-19, but also the social impacts of the disease (e.g. effects of strategies to support parents with home-schooling their children and educators with online learning pedagogical strategies; consequences of police being mobilized to police quarantines; and international development issues such as food security during the pandemic).
    keywords: covid-19; data; evidence; replication; reviews; studies
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        item: #1743 of 7819
          id: cord-271404-tu8u1b1d
      author: Gaunkar, Ridhima B
       title: COVID-19 in Smokeless Tobacco Habitués: Increased Susceptibility and Transmission
        date: 2020-06-25
       words: 3096
      flesch: 45
     summary: It is imperative to prioritize research aimed at exploring the potential association of SLT use with COVID-19 to develop evidence-based policy options. Issuing rigorous regulations to restrict the use of various forms of SLT products and the obnoxious act of spitting in public can assist in arresting the spread of COVID-19.
    keywords: covid-19; habitués; saliva; sars; slt; tobacco; transmission; use
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        item: #1744 of 7819
          id: cord-271407-wrhjnz8w
      author: Greco, Francesco
       title: Impact of COVID-19 pandemic on health-related quality-of-life in uro-oncologic patients: what should we wait for?
        date: 2020-07-17
       words: 2437
      flesch: 37
     summary: Our way to make medicine has been drastically changed and in Italy doctors have been involved in this emergency and in the therapy of COVID-19 patients, disregarding their specialization. From the 1 st March to the 26 th April 2020 as the daily rate of COVID-19 patients admitted to intensive care units has consistently been between 9% and 11% of all patients who are actively infected, our hospital decided to reduce surgical activity and since then only 3 robot-assisted radical prostatectomies (RARPs) for high-risk prostate cancer were performed at our department.
    keywords: anxiety; cancer; covid-19; health; median; patients
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        item: #1745 of 7819
          id: cord-271416-53qxs7ge
      author: Zhou, Kehua
       title: Towards precision management of cardiovascular patients with COVID-19 to reduce mortality
        date: 2020-04-28
       words: 1100
      flesch: 35
     summary: People with a better tolerance to hypoxia usually reside in high altitudes. In a meta-analysis on high-altitude adaptation, researchers found that populations residing at high altitudes were more likely to have ACE gene
    keywords: ace; altitude; covid-19
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        item: #1746 of 7819
          id: cord-271425-ysdw31nq
      author: Carson, R. T.
       title: COVID-19's U.S. Temperature Response Profile
        date: 2020-11-05
       words: 13186
      flesch: 49
     summary: (1) that uses death count data aggregated into seven-day periods, WeeklyDeadit = Σt DailyDeadit, where the summation is over t=1 to t=7. By reconstructing the set of death counts states report daily, largely by substituting in retroactive corrections based on death certificate dates, we are able to reliably estimate the TRP for COVID-19 deaths.
    keywords: copyright; counts; covid-19; data; death; display; funder; holder; license; medrxiv preprint; model; november; perpetuity; preprint; state; temperature; version
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        item: #1747 of 7819
          id: cord-271432-pn02p843
      author: Banerjee, Tannista
       title: U.S. county level analysis to determine If social distancing slowed the spread of COVID-19
        date: 2020-07-06
       words: 3745
      flesch: 58
     summary: Social distancing measures were created from Safegraph [7] social distancing database. Further, we concentrated on social distancing measures at individual county level because we matched the above social distancing measures with county level COVID-19 infections data and NPIs data.
    keywords: counties; county; covid-19; data; distancing; home; npis; social; time
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        item: #1748 of 7819
          id: cord-271469-lozvq3y6
      author: Shaikh, Faiq
       title: Current landscape of Imaging and the potential role for Artificial intelligence in the management of COVID-19
        date: 2020-06-27
       words: 3043
      flesch: 38
     summary: The Journal of Clinical Investigation Imaging Profile of the COVID-19 Infection: Radiologic Findings and Literature Review Frequency and distribution of chest radiographic findings in COVID-19 positive patients Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection Findings of acute pulmonary embolism in COVID-19 patients. The clinical presentation of COVID-19 COVID-19 is primarily a respiratory tract infection caused by the SARS-CoV2 virus.
    keywords: covid-19; disease; imaging; infection; patients; sars
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        item: #1749 of 7819
          id: cord-271483-33kuvpl7
      author: Shojaei, Amirahmad
       title: COVID-19 and off label use of drugs: an ethical viewpoint
        date: 2020-05-08
       words: 3185
      flesch: 38
     summary: key: cord-271483-33kuvpl7 authors: Shojaei, Amirahmad; Salari, Pooneh title: COVID-19 and off label use of drugs: an ethical viewpoint date: 2020-05-08 journal: Daru DOI: 10.1007/s40199-020-00351-y sha: doc_id: 271483 cord_uid: 33kuvpl7 BACKGROUND: They may apply so many different off-label medications even the ones with the weakest evidence in hope of rescuing COVID-19 positive patients, whose life is seriously threatening.
    keywords: covid-19; label; medications; patients; practice; research; use
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        item: #1750 of 7819
          id: cord-271504-t3y1w9ef
      author: Luo, Zichao
       title: Combating the Coronavirus Pandemic: Early Detection, Medical Treatment, and a Concerted Effort by the Global Community
        date: 2020-06-16
       words: 14501
      flesch: 38
     summary: Structural basis of influenza virus fusion inhibition by the antiviral drug Arbidol New small-molecule drug design strategies for fighting resistant influenza A Characteristics of arbidol-resistant mutants of influenza virus: implications for the mechanism of anti-influenza action of arbidol Mechanism of inhibition of enveloped virus membrane fusion by the antiviral drug arbidol Membranotropic effects of arbidol, a broad antiviral molecule, on phospholipid model membranes Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment Discovering drugs to treat coronavirus disease 2019 (COVID-19) Effects of chloroquine on viral infections: an old drug against today's diseases Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology Chloroquine inhibits autophagic flux by decreasing autophagosomelysosome fusion New insights into the antiviral effects of chloroquine Anti-HIV effects of chloroquine: inhibition of viral particle glycosylation and synergism with protease inhibitors Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro Chloroquine is a potent inhibitor of SARS coronavirus infection and spread In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Breakthrough: chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Chloroquine and hydroxychloroquine as available weapons to fight COVID-19 In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Effects of chronic exposure to hydroxychloroquine or chloroquine on inner retinal structures Animal toxicity and pharmacokinetics of hydroxychloroquine sulfate Retroviral proteases and their roles in virion maturation Host cell proteases: critical determinants of coronavirus tropism and pathogenesis Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts Research and development on therapeutic agents and vaccines for COVID-19 and related human coronavirus diseases Virusencoded proteinases and proteolytic processing in the Nidovirales The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry Protease inhibitors targeting coronavirus and filovirus entry Efficacy of camostat mesilate compared with famotidine for treatment of functional dyspepsia: is camostat mesilate effective? Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity Recent research by Hoffmann et al. showed a promising in vitro inhibitory effect of this serine protease inhibitor in SARS-CoV and 2019-nCoV on human lung cells, showing potential as a viable option for COVID-19 treatment [113] .
    keywords: amplification; antibodies; antiviral; cells; china; chloroquine; coronavirus; covid-19; crispr; detection; disease; dna; drug; genome; host; infection; lamp; mers; ncov; novel; nucleic; patients; pcr; potential; protease; protein; rna; sars; syndrome; therapeutic; treatment
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        item: #1751 of 7819
          id: cord-271525-sgrr0mat
      author: Sinha, Rahul
       title: Infantile spasms and COVID-19: Challenges and solutions in resource-limited settings
        date: 2020-08-18
       words: 1145
      flesch: 44
     summary: key: cord-271525-sgrr0mat authors: Sinha, Rahul; Anand, Vaishakh; Gupta, Juhi; Singh, Sonali; Gulati, Sheffali title: Infantile spasms and COVID-19: Challenges and solutions in resource-limited settings date: 2020-08-18 journal: Epilepsy Res DOI: 10.1016/j.eplepsyres.2020.106441 sha: doc_id: 7. Video links are provided to caretakers explaining various age-appropriate stretching exercises and developmental stimulation techniques http://pedneuroaiims.org/developmental-stimulation.html Summary of recommendations for the management of infantile seizures: Task Force Report for the ILAE Commission of Pediatrics Temporal dynamics in viral shedding and transmissibility of COVID-19 Developmental and epilepsy outcomes at age 4 years in the UKISS trial comparing hormonal treatments to vigabatrin for infantile spasms: a multi-centre randomised trial.
    keywords: children; eeg; spasms; therapy
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        item: #1752 of 7819
          id: cord-271528-ob4l0bcf
      author: Bar-Zeev, Naor
       title: COVID-19 vaccines: early success and remaining challenges
        date: 2020-09-04
       words: 1506
      flesch: 46
     summary: key: cord-271528-ob4l0bcf authors: Bar-Zeev, Naor; Inglesby, Tom title: COVID-19 vaccines: early success and remaining challenges date: 2020-09-04 journal: Lancet DOI: 10.1016/s0140-6736(20)31867-5 sha: doc_id: 271528 cord_uid: ob4l0bcf nan In The Lancet, Denis Y Logunov and colleagues from the N F Gamaleya Research Institute of Epidemiology and Microbiology in Russia present findings from two phase 1/2, non-randomised, open-label studies of a heterologous, replication-deficient, recombinant adenovirus vector-based vaccine in both frozen and lyophilised formulations. Showing safety will be crucial with COVID-19 vaccines, not only for vaccine acceptance but also for trust in vaccination broadly.
    keywords: covid-19; safety; studies; vaccine
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        item: #1753 of 7819
          id: cord-271575-n70rqs8c
      author: Jager, Kitty J.
       title: Results from the ERA-EDTA Registry indicate a high mortality due to COVID-19 in dialysis patients and kidney transplant recipients across Europe.
        date: 2020-10-15
       words: 3044
      flesch: 44
     summary: As mortality is generally far lower in transplant patients compared with dialysis patients, their mortality risk was multiplied by 92.7 (95%CI 61.0 to 140.7) when compared to their non COVID-19 matched controls ( Figure 1 ). This sampling bias may explain our finding that transplant patients are at higher risk of death than dialysis patients of similar propensity score.
    keywords: age; covid-19; dialysis; mortality; patients; risk; transplant
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        item: #1754 of 7819
          id: cord-271582-xo2a4wnj
      author: Chew, Christopher
       title: Medical ethics in the era of COVID‐19: Now and the future
        date: 2020-08-05
       words: 1169
      flesch: 40
     summary: At the time of writing, over a hundred articles on COVID-19 clinical ethics have been published-a testament to one of the most clinically, personally and ethically challenging experiences in living memory. Similarly, COVID-19 has forced healthcare workers in developed countries to confront moral dilemmas that have received limited attention from policymakers, clinicians and ethicists until now, but are part of daily life for their counterparts in resource-poor nations.
    keywords: covid-19; healthcare; pandemic; public
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        item: #1755 of 7819
          id: cord-271599-1yu1yl12
      author: Bailey, Stacy Cooper
       title: Changes in COVID-19 Knowledge, Beliefs, Behaviors, and Preparedness Among High-Risk Adults from the Onset to the Acceleration Phase of the US Outbreak
        date: 2020-09-01
       words: 4056
      flesch: 49
     summary: In multivariable analyses, black adults and those with lower health literacy were more likely to report less perceived susceptibility to COVID-19 (black adults: relative risk (RR) 1.62, 95% confidence interval (CI) 1.07–2.44, p = 0.02; marginal health literacy: RR 1.96, 95% CI 1.26–3.07, p < 0.01). Individuals with low health literacy remained more likely to feel unprepared for the outbreak (RR 1.80, 95% CI 1.11–2.92, p = 0.02) and to express confidence in the federal government response (RR 2.11, 95% CI 1.49–3.00, p < 0.001)
    keywords: adults; covid-19; health; literacy; outbreak; participants; wave
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        item: #1756 of 7819
          id: cord-271603-zy4l9vtf
      author: Skali, Hicham
       title: Guidance and Best Practices for Reestablishment of Non-Emergent Care in Nuclear Cardiology Laboratories During the Coronavirus Disease 2019 (COVID-19) Pandemic: An Information Statement from ASNC, IAEA, and SNMMI
        date: 2020-10-17
       words: 3729
      flesch: 39
     summary: During the COVID-19 pandemic, many trainees have been redeployed from their imaging rotations to clinical care of COVID-19 patients in the hospital and intensive care units. The American Society of Nuclear Cardiology (ASNC) and the Society of Nuclear Medicine and Molecular Imaging (SNMMI) issued an Information Statement 3 with guidance for nuclear cardiology laboratories during the COVID-19 pandemic in late March 2020 that also recommended delaying all non-urgent studies.
    keywords: cardiology; covid-19; healthcare; laboratories; laboratory; pandemic; patients; stress; testing
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        item: #1757 of 7819
          id: cord-271653-4q2olzx1
      author: Libby, Peter
       title: The Heart in COVID19: Primary Target or Secondary Bystander?
        date: 2020-04-10
       words: 1590
      flesch: 29
     summary: But act today we must, and understanding the multiplicity of mechanisms of myocardial injury in COVID-19 infection will help us meet our mission unsupported by the comfort of strong data. But act today we must, and understanding the multiplicity of mechanisms of myocardial injury in COVID-19 infection will help us meet our mission unsupported by the comfort of strong data.
    keywords: covid-19; infection; injury
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        item: #1758 of 7819
          id: cord-271698-n9qd14oe
      author: Dy, Louie Florendo
       title: A COVID-19 infection risk model for frontline health care workers
        date: 2020-08-08
       words: 3852
      flesch: 45
     summary: • Increased spacing, frequent cleaning of work spaces, and compartmentalizing the rooms of patients in open space decrease the risk of infection not only for health care workers but also for the other patients who are COVID-19 negative or non-person-under-investigation (PUI) (Nishiura et al. 2020 the most infectious), must be given extra protection, and hospital policies must minimize their duration of exposure and the number of patients they encounter or interact with per shift. Decreasing the infection risks faced by each health care worker per day, coupled with superior health, well-being and welfare practices, will result in a robust health care Wearing a full body biohazard suit ≈ 1.00 Absolute protection; either being totally absent from the job or out of shift, or being in full and functional PPE (N95 masks, face and eye shields, gloves, biohazard suit); strict compliance with hand hygiene; having effective engineering controls Table 4 Proposed risk assessment based on overall risk score Overall Risk Score Risk assessment 0 to less than 0.5 Low risk 0.5 to less than 1.0 Moderate risk Greater than or equal to 1.0 High risk Table 5 Sample scenarios of frontline health care workers and their corresponding risk score High risk In this study, we formulated a mathematical model to calculate the risk of being infected in health care facilities.
    keywords: care; covid-19; duration; health; hour; number; patients; risk
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        item: #1759 of 7819
          id: cord-271764-um001ffd
      author: Garraud, Olivier
       title: Passive immunotherapy with convalescent plasma against COVID-19? What about the evidence base and clinical trials?
        date: 2020-06-27
       words: 1307
      flesch: 30
     summary: Possible mechanisms of action Convalescent Plasma Therapy for Covid-19: State of the Art Effect of Convalescent Plasma Therapy on Viral Shedding and Survival in COVID-19 Patients Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma Effectiveness of convalescent plasma therapy in severe COVID-19 patients Testing an Old Therapy Against a New Disease: Convalescent Plasma for COVID-19 Collecting and evaluating convalescent plasma for COVID-19 treatment: why and how? It would be urged that there is a general preparedness plan to evaluate the assets and liabilities of convalescent plasma to treat emergent infections; as a matter of fact, plasma therapy of convalescent plasma has not been thought of in a recent position paper on preparedness plans [25] .
    keywords: convalescent; covid-19; plasma; therapy
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        item: #1760 of 7819
          id: cord-271781-cfv0ta10
      author: Patel, Kishan P.
       title: Transmission of SARS-CoV-2: an update of current literature
        date: 2020-07-07
       words: 4478
      flesch: 39
     summary: Environmental contamination through airflow may perpetuate viral transmission through infectious droplets [25] . A study analyzing COVID-19 patients from three hospitals in China demonstrated higher positive rates of viral RNA in bronchoalveolar lavage fluid, sputum, and
    keywords: coronavirus; cov-2; covid-19; patients; rna; sars; study; transmission
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        item: #1761 of 7819
          id: cord-271810-7uzk4pi9
      author: Soriano, Joan B.
       title: Humanistic Epidemiology: Love in the time of cholera, COVID-19 and other outbreaks
        date: 2020-04-25
       words: 1950
      flesch: 60
     summary: But other Madrid hospitals were hit even harder; colleagues at Hospital La Paz or Gregorio Marañón, were suffering an even worse avalanche of patients to care for. It is still severely and seriously affecting our old ones and others with heart, lung and other chronic diseases.
    keywords: cholera; covid-19; hospital; patients; time
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        item: #1762 of 7819
          id: cord-271813-nroflfmc
      author: Deng, Wang
       title: Positive results for patients with COVID-19 discharged form hospital in Chongqing, China
        date: 2020-06-19
       words: 2428
      flesch: 41
     summary: In addition, there is a lack of clinical characteristics, the potential impact and significance of positive patients recovered from COVID-19, which makes it difficult to provide clinical evidence and experience for the management of patients with COVID-19 in the recovery period. With the increasing number of recovered patients, more attention should be paid to the follow-up of these patients.
    keywords: cov-2; covid-19; hospital; patients; results; sars
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        item: #1763 of 7819
          id: cord-271814-a2vlkwce
      author: Brough, Helen A.
       title: Managing childhood allergies and immunodeficiencies during respiratory virus epidemics – The 2020 COVID‐19 pandemic: A statement from the EAACI‐section on pediatrics
        date: 2020-05-31
       words: 2934
      flesch: 39
     summary: The care of children with allergies or immune conditions is being adapted to the current situation, with more remote working and providing guidance to children to reduce likelihood of infection in children who would be deemed at higher risk of severe COVID-19 disease. Stem Cells Dev Functional exhaustion of antiviral lymphocytes in COVID-19 patients Why the immune system fails to mount an adaptive immune response to a COVID -19 infection Clinical and immunologic features in severe and moderate Coronavirus Disease Parenting in a time of COVID-19 Shielding advice for very high-risk groups American College of Allergy, Asthma & Immunology Position Paper on the Use of Telemedicine for Allergists Managing childhood allergies and immunodeficiencies during respiratory virus epidemics -The
    keywords: asthma; children; covid-19; disease; pandemic; patients; risk
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        item: #1764 of 7819
          id: cord-271840-cw2xy1m6
      author: Majmundar, Neil
       title: Incidence, Pathophysiology, and Impact of Coronavirus Disease 2019 (COVID-19) on Acute Ischemic Stroke
        date: 2020-09-23
       words: 1227
      flesch: 43
     summary: While younger patients may be presenting with LVOs, many stroke centers across the world have anecdotally reported a decline in the total number of patients presenting with an ischemic stroke during the height of the pandemic. Cardiovascular considerations for patients, health care workers, and health systems during the COVID-19 pandemic Severe acute respiratory syndrome coronavirus 2 infection and ischemic stroke Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China Large-vessel stroke as a presenting feature of covid-19 in the young Incidence, characteristics and outcomes of large vessel stroke in COVID-19 cohort: a multicentric international study Hypercoagulation and antithrombotic treatment in coronavirus 2019: a new challenge Society of NeuroInterventional Surgery recommendations for the care of emergent neurointerventional patients in the setting of COVID-19 Falling stroke rates during COVID-19 pandemic at a Comprehensive Stroke Center: cover title: falling stroke rates during COVID-19 Collateral effect of covid-19 on stroke evaluation in the United States Delayed presentation of acute ischemic strokes during the COVID-19 crisis From the Departments of 1 Neurological Surgery and 2 1878-8750/$ -see front matter ª 2020 Published by
    keywords: covid-19; patients; risk; stroke
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        item: #1765 of 7819
          id: cord-271853-wexe9gq0
      author: Lu, Quan
       title: Social Policy Responses to the Covid-19 Crisis in China in 2020
        date: 2020-08-14
       words: 8436
      flesch: 37
     summary: (4) For medical institutions admitting a large number of patients, social medical insurance would prepay funds to ensure that the effectiveness of treatment from hospitals is not impaired due to payment policies. Different types of social policy programs have been combined and synthesized, including social insurance, social assistance, and social welfare arrangements.
    keywords: assistance; china; covid-19; crisis; insurance; pandemic; policy; security; social; state; system; unemployment; welfare
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        item: #1766 of 7819
          id: cord-271855-k8zlptas
      author: Davis, Corey S.
       title: Opioid Policy Changes During the COVID-19 Pandemic - and Beyond
        date: 2020-05-20
       words: 1587
      flesch: 45
     summary: Kill 100,000 to 240,000 in U.S. Despite Actions, Officials Say Overdose Death Rates Opioid agonist treatment for pharmaceutical opioid dependent people Mortality risk during and after opioid substitution treatment: systematic review and meta-analysis of cohort studies Opioid overdose rates and implementation of overdose education and nasal naloxone distribution in Massachusetts: interrupted time series analysis Are needle and syringe programmes associated with a reduction in HIV transmission among people who inject drugs: a systematic review and meta-analysis Legal and policy changes urgently needed to increase access to opioid agonist therapy in the United States Over the counter naloxone needed to save lives in the United States Paraphernalia laws, criminalizing possession and distribution of items used to consume illicit drugs, and injection-related harm An epidemic in the midst of a pandemic: opioid use disorder and COVID-19 Substance Abuse and Mental Health Services Administration. In an attempt to reduce preventable harm to individuals with opioid use disorder (OUD), federal, state, and local governments have temporarily modified law and policy to increase access to OUD treatment and divert some individuals at high risk away from the correctional system.
    keywords: individuals; opioid; oud; treatment
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        item: #1767 of 7819
          id: cord-271867-n563yqw4
      author: Falicov, Celia
       title: Expanding Possibilities: Flexibility and Solidarity with Under Resourced Immigrant Families During the Covid‐19 Pandemic
        date: 2020-07-14
       words: 8997
      flesch: 45
     summary: Three of the clinics offer mental health services. Immigrant Latinx patients are more likely to seek or accept mental health services within a community medical setting than independently seeking these services when they suffer depression, anxiety, trauma or relational conflicts (Falicov, 2014; Valdez et al., 2011; Vega et al., 2001) .
    keywords: article; care; clients; clinic; community; copyright; covid-19; families; family; group; health; new; patients; phone; psychotherapy; services; students; time
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        item: #1768 of 7819
          id: cord-271870-8v9w3sps
      author: Lee, David
       title: Testing on the Move South Korea’s rapid response to the COVID-19 pandemic
        date: 2020-04-21
       words: 4569
      flesch: 48
     summary: Abstract The emergence of COVID-19 in South Korea, and the public and private sector response to it, serves as a valuable case study for countries facing similar outbreaks. Health officials in South Korea recognized the threat this outbreak posed to their nation, a close neighbor and trading partner with China.
    keywords: contact; covid-19; government; health; information; kcdc; korea; patients; public; self; south; testing
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        item: #1769 of 7819
          id: cord-271871-8grkln6o
      author: Singer, J. S.
       title: Low Prevalence (0.13%) of COVID-19 Infection in Asymptomatic Pre-operative/Pre-procedure Patients at a Large Academic Medical Center Informs Approaches to Perioperative Care
        date: 2020-08-14
       words: 2844
      flesch: 36
     summary: The overall very low numbers of COVID-19 positive patients in our data set 374 preclude the ability to extrapolate significance of this finding. The prevalence of asymptomatic COVID-19 infection was 0.13%.
    keywords: asymptomatic; covid-19; infection; patients; pre; procedures; testing
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        item: #1770 of 7819
          id: cord-271887-blwrpf38
      author: Sampa, Masuda Begum
       title: Redesigning Portable Health Clinic Platform as a Remote Healthcare System to Tackle COVID-19 Pandemic Situation in Unreached Communities
        date: 2020-06-30
       words: 5658
      flesch: 43
     summary: Public health experts are working at relieving pressure on healthcare facilities so resources can be focused on COVID-19 patients. Moreover, findings indicate that frontline medical staff experience heightened levels of stress when coming into direct contact with COVID-19 patients.
    keywords: covid-19; disease; health; healthcare; ncds; patients; people; phc; risk; services; system; worker
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        item: #1771 of 7819
          id: cord-271889-qlmp0qul
      author: Bhat, Roopa
       title: Chest Imaging in Patients Hospitalized With COVID-19 Infection - A Case Series
        date: 2020-04-11
       words: 2298
      flesch: 44
     summary: A novel coronavirus from patients with pneumonia in China The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health -The latest 2019 novel coronavirus outbreak in Wuhan, China WHO Director-General's opening remarks at the media briefing on COVID-19 -11 An interactive web-based dashboard to track COVID-19 in real time Chest CT findings in patients with corona virus disease 2019 and its relationship with clinical features Clinical features and chest CT manifestations of coronavirus disease 2019 (COVID-19) in a single-center study in Shanghai, China Middle East respiratory syndrome coronavirus (MERS-CoV) infection: Chest CT findings CT correlation with outcomes in 15 patients with acute middle east respiratory syndrome coronavirus A correlation between the severity of lung lesions on radiographs and clinical findings in patients with severe acute respiratory syndrome Frequency and distribution of chest radiographic findings in COVID-19 positive patients Radiological Society of North America expert consensus statement on reporting chest CT findings related to COVID-19 Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA Chest CT findings in coronavirus disease-19 (COVID-19): Relationship to duration of infection Coronavirus disease 2019 (COVID-19): Role of chest CT in diagnosis and management CT Imaging and Differential Diagnosis of COVID-19. This case series aims to outline the clinical features, illustrates the most common reported imaging findings of COVID-19 infection, and demonstrates different management plans used.
    keywords: chest; covid-19; cxr; fig; opacities; patients
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        item: #1772 of 7819
          id: cord-271896-1ad18z11
      author: Janowitz, Tobias
       title: Famotidine use and quantitative symptom tracking for COVID-19 in non-hospitalised patients: a case series
        date: 2020-06-04
       words: 3629
      flesch: 44
     summary: key: cord-271896-1ad18z11 authors: Janowitz, Tobias; Gablenz, Eva; Pattinson, David; Wang, Timothy C; Conigliaro, Joseph; Tracey, Kevin; Tuveson, David title: Famotidine use and quantitative symptom tracking for COVID-19 in non-hospitalised patients: a case series date: 2020-06-04 journal: Gut DOI: 10.1136/gutjnl-2020-321852 sha: doc_id: 271896 cord_uid: 1ad18z11 OBJECTIVE: Treatment options for non-hospitalised patients with coronavirus disease 2019 (COVID-19) to reduce morbidity, mortality and spread of the disease are an urgent global need.
    keywords: covid-19; days; famotidine; patients; scores; symptoms; times
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        item: #1773 of 7819
          id: cord-271906-2nm55024
      author: Quincho-Lopez, Alvaro
       title: Case Report: Pneumothorax and Pneumomediastinum as Uncommon Complications of COVID-19 Pneumonia—Literature Review
        date: 2020-07-23
       words: 1987
      flesch: 40
     summary: Emergency tracheal intubation in 202 patients with COVID-19 in Wuhan, China: lessons learnt and international expert recommendations Portable chest X-ray in coronavirus disease-19 (COVID-19): a pictorial review Coronavirus disease 2019 (COVID-19): a systematic review of imaging findings in 919 patients COVID-19 with spontaneous pneumomediastinum Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study SARS-CoV-2 pulmonary infection revealed by subcutaneous emphysema and pneumomediastinum Pneumomediastinum and spontaneous pneumothorax as an extrapulmonary complication of COVID-19 disease Spontaneous pneumothorax: epidemiology, pathophysiology and cause Spontaneous pneumomediastinum: time for consensus Spontaneous pneumothorax Systematic review of spontaneous pneumomediastinum: a survey of 22 years' data Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia Mediastinal emphysema, giant bulla, and pneumothorax developed during the course of COVID-19 pneumonia SARS-CoV-2 pneumonia with subcutaneous emphysema, mediastinal emphysema, and pneumothorax: a case report Spontaneous pneumomediastinum in COVID-19 COVID-19 with spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema Spontaneous pneumothorax and subcutaneous emphysema in COVID-19 patient: case report Perforated acute abdomen in a patient with COVID-19: an atypical manifestation of the disease Spontaneous pneumothorax following COVID-19 pneumonia SARS-CoV-2 infection associated with spontaneous pneumothorax Secondary tension pneumothorax in a COVID-19 pneumonia patient: a case report Tension pneumothorax in a patient with COVID-19 Management of persistent pneumothorax with thoracoscopy and blebs resection in COVID-19 patients Comparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses Spontaneous pneumomediastinum occurring in the SARS-COV-2 infection Spontaneous pneumomediastinum in a patient with coronavirus disease 2019 pneumonia and the possible underlying mechanism Spontaneous pneumomediastinum: a probable unusual complication of coronavirus disease 2019 (COVID-19) pneumonia We performed a literature review of COVID-19 pneumonia cases that developed pneumothorax, pneumomediastinum, or both.
    keywords: covid-19; patients; pneumomediastinum; pneumonia; pneumothorax
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        item: #1774 of 7819
          id: cord-271920-1dzkgt6w
      author: Carpenter, Christopher R.
       title: Diagnosing COVID‐19 in the Emergency Department: A Scoping Review of Clinical Exam, Labs, Imaging Accuracy and Biases
        date: 2020-06-16
       words: 7256
      flesch: 41
     summary: For example, among COVID-19 patients from cruise ships evaluated with CT, those with symptoms more commonly had COVID-19 CT findings than those without symptoms (80% vs. 40%). Emergency departments (ED) encountered decreased patient volumes before some in Seattle, New York City, New Orleans, and Detroit experienced waves of COVID-19 patients mixed with asymptomatic patients or those concerned about potential exposures.
    keywords: accuracy; article; copyright; coronavirus; cov-2; covid-19; disease; negative; patients; pcr; rrt; sars; sensitivity; tests
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        item: #1775 of 7819
          id: cord-271930-9a18h2tr
      author: Licari, Amelia
       title: Allergy and asthma in children and adolescents during the COVID outbreak: What we know and how we could prevent allergy and asthma flares
        date: 2020-05-28
       words: 1178
      flesch: 40
     summary: Allergic children had a significantly higher (P < .0001) eosinophil count than COVID-19 patients. Even five (12.5%) COVID-19 children have no (0) eosinophil.
    keywords: children; covid-19; patients
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        item: #1776 of 7819
          id: cord-271944-oxtus5vb
      author: Joseph, Rudman
       title: Seizure And COVID-19: Association and Review of Potential Mechanism
        date: 2020-10-13
       words: 2363
      flesch: 42
     summary: We will be concluding the paper by briefly discussing the three possible seizure development mechanisms in patients infected with SARS- COV 2, which includes - (a) Direct Mechanism (b) Indirect Mechanism and (c) Exacerbation of Seizure in Patients with Epilepsy (PWE). We have discussed the electroencephalogram (EEG), imaging, and Cerebrospinal fluid (CSF) findings in COVID-19 patients presenting with seizure.
    keywords: coronavirus; cov-2; covid-19; patients; sars; seizures
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        item: #1777 of 7819
          id: cord-271957-osaycpe8
      author: Zuin, Marco
       title: Arterial hypertension and risk of death in patients with COVID-19 infection: systematic review and meta-analysis
        date: 2020-04-11
       words: 1197
      flesch: 38
     summary: We therefore perform a systematic review and meta-analysis to evaluate the risk of death in COVID-19 infection patients with and without HT. The association between the presence of HT and a poor outcome in COVID-19 patients was partially demonstrated in single analysis, but never into a meta-analysis [6, 9] .
    keywords: covid-19; patients; risk
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        item: #1778 of 7819
          id: cord-271980-8x5g8r7c
      author: Yao, Ye
       title: Ambient nitrogen dioxide pollution and spread ability of COVID-19 in Chinese cities
        date: 2020-09-30
       words: 3481
      flesch: 40
     summary: The relationship between NO 2 concentration and R 0 of COVID-19 may be mediated by population density or other air pollutants, such as city population and city area. To eliminate the effects of city population and city area on the relationship between NO 2 concentration and R 0 value, we applied a mediation analysis to verify whether more densely populated cities had both greater R 0 and NO 2 concentration values.
    keywords: cities; city; concentration; covid-19; hubei
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        item: #1779 of 7819
          id: cord-272015-1anph6qi
      author: Dauby, Nicolas
       title: The unfinished story of hydroxychloroquine in COVID-19: the right anti-inflammatory dose at the right moment?
        date: 2020-10-17
       words: 962
      flesch: 7
     summary: In the same line, ongoing trials are investigating colchicine to prevent hospitalisation in SARS-CoV-2 infected subjects, and the rationale is based on anti-inflammatory properties, that are partly shared Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19 The association of treatment with hydroxychloroquine and hospital mortality in COVID-19 patients Hydroxychloroquine: from malaria to autoimmunity Lupus Anticoagulant and Abnormal Coagulation Tests in Patients with Covid-19 Hydroxychloroquine Use Is Associated with Lower Odds of Persistently Positive Antiphospholipid Antibodies and/or Lupus Anticoagulant in Systemic Lupus Erythematosus Low-dose hydroxychloroquine therapy and mortality in hospitalised patients with COVID-19: a nationwide observational study of 8075 participants Use of hydroxychloroquine in hospitalised COVID-19 patients is associated with reduced mortality: Findings from the observational multicentre Italian CORIST study An inflammatory cytokine signature predicts COVID-19 severity and survival Longterm hydroxychloroquine use in patients with rheumatic conditions and development of SARS-CoV-2 infection: a retrospective cohort study Chloroquine inhibits the release of inflammatory cytokines by human lung explants Mortality in COVID-19 patients with acute respiratory distress syndrome and corticosteroids use: a systematic review and meta-analysis Chloroquine inhibits production of TNF-α, IL-1β and IL-6 from lipopolysaccharide-stimulated human monocytes/macrophages by different modes Early Hydroxychloroquine but not Chloroquine use reduces ICU admission in COVID-19 patients High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates Colchicine as a possible therapeutic option in COVID-19 infection Selective regulation of cytokine secretion by hydroxychloroquine: inhibition of interleukin 1 alpha (IL-1-alpha) and IL-6 in human monocytes and T cells Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19 Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study World Health Organization Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19 HCQ inhibits the production of the pro-inflammatory cytokines interleukin (IL)-6, TNF-α and IL-1-β by activated macrophages (Sperber et al. 1993; Jang et al. 2006) , which are notoriously associated with COVID-19 severity (Webb et al.; Del Valle et al. 2020 ) and also the production of chemotactic cytokines involved in the recruitment of pro-inflammatory cells in the lungs(Grassin-Delyle et al. 2020).
    keywords: covid-19; patients
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        item: #1780 of 7819
          id: cord-272054-9udb4djk
      author: Krishnamoorthy, Parasuram
       title: Biventricular strain by speckle tracking echocardiography in COVID-19: findings and possible prognostic implications
        date: 2020-08-04
       words: 2284
      flesch: 40
     summary: We report firstly that, while we were able to measure biventricular mechanics in only 12% of all TTEs performed in our hospital for COVID-19 patients, both RVGS and RVFWS were significantly decreased in patients with poor outcomes; and secondly that LVGLS was severely decreased in all patients regardless of their outcome (either survival to discharge or death) and/or requirement for endotracheal intubation. To our knowledge, this is the first study in the literature evaluating biventricular mechanics by simultaneous LV and RV strain imaging in COVID-19 patients.
    keywords: covid-19; echocardiography; patients; strain; ventricular
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        item: #1781 of 7819
          id: cord-272067-241tx1v7
      author: González-Blanco, Leticia
       title: COVID-19 lockdown in people with severe mental disorders in Spain: Do they have a specific psychological reaction compared with other mental disorders and healthy controls?
        date: 2020-07-25
       words: 4204
      flesch: 44
     summary: Of those, 125 had severe mental disorders consisting of 65 cases of bipolar disorder (BD) and 60 of psychotic disorders (severe mental disorder group -SMD), 250 had other current mental disorders consisting of 125 cases of depression and 125 of anxiety (common mental disorder control group -CMD), and 250 had no current or past mental disorders (healthy control group -HC). Multiple concurrent factors can contribute to increased fear or anxiety, including the physical distancing and self-isolation strategies used to contain the spread of the infectious agent (Brooks et al., 2020) .
    keywords: anxiety; mental; people; smd
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        item: #1782 of 7819
          id: cord-272071-445ivhx0
      author: Wunsch, Hannah
       title: Mechanical Ventilation in COVID-19: Interpreting the Current Epidemiology
        date: 2020-07-01
       words: 2633
      flesch: 40
     summary: Severe steroid-resistant asthma affects 5-10% of adult patients, who disproportionately account for 50-80% of all asthma-associated healthcare costs (6) . key: cord-272071-445ivhx0 authors: Wunsch, Hannah title: Mechanical Ventilation in COVID-19: Interpreting the Current Epidemiology date: 2020-07-01 journal: Am J Respir Crit Care Med DOI: 10.1164/rccm.202004-1385ed sha: doc_id: 272071 cord_uid: 445ivhx0 nan The world is scrutinizing every cohort and every outcome for patients with coronavirus disease , particularly the most critically ill who are receiving mechanical ventilation.
    keywords: care; covid-19; data; mortality; patients; ventilation
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        item: #1783 of 7819
          id: cord-272112-egsha2j7
      author: Tartarone, Alfredo
       title: COVID-19 and cancer care: what do international guidelines say?
        date: 2020-08-07
       words: 2415
      flesch: 35
     summary: modes -oftrans missi on-of-virus -causi ng-covid -19-impli catio ns-for-ipcpreca ution -recom menda tions Estimates of the severity of coronavirus disease 2019: a model-based analysis Clinical characteristics of CIVID-19 infected cancer patients: a retrospective case study in three hospitals within Wuhan Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China SARS-CoV-2 transmission in patients with cancer at a tertiary care hospital in Wuhan, China Characteristics of COVID-19 patients dying in Italy Case fatality rate of cancer patients with COVID-19 in a New York Hospital system Rischio infettivo da coronavirus COVID 19: indicazioni per l'oncologia La gestione delle pazienti con carcinoma mammario durante la pandemia COVID-19 versione 25 Aprile 2020 Consequently cancer patients are at very high risk for COVID-19 infection considering that they often present multiple risk factors as well as older age, immunosuppressed state due to anticancer treatment and several comorbidities (e.g., chronic lung disease, diabetes, cardiovascular diseases).
    keywords: cancer; covid-19; infection; pandemic; patients; risk; treatment
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        item: #1784 of 7819
          id: cord-272128-93tmtji8
      author: Becher, Yael
       title: D-dimer and C-reactive Protein Blood Levels Over Time Used to Predict Pulmonary Embolism in Two COVID-19 Patients
        date: 2020-05-20
       words: 1107
      flesch: 46
     summary: Prevention and treatment of venous thromboembolism associated with coronavirus disease 2019 infection: a consensus statement before guidelines Clinical characteristics of 3,062 COVID-19 patients: a meta-analysis Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Acute pulmonary embolism in COVID-19 patients on CT angiography and relationship to D-dimer levels Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia We believe that an opposite change in the blood levels of both biomarkers over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients.
    keywords: blood; dimer; levels
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        item: #1785 of 7819
          id: cord-272137-enfxk1ku
      author: Choo, Esther K
       title: COVID-19 fault lines
        date: 2020-04-23
       words: 857
      flesch: 65
     summary: No one would think to provide the luxury of sufficient space and staff to, say, enable the kind of social distancing space between occupants that is recommended in the midst of the coronavirus disease 2019 (COVID-19) pandemic. But as we scramble to distribute limited resources such as tests and hospital equipment andultimately-therapies and a vaccine, we must be careful to avoid reinforcing existing fault lines going forward.
    keywords: covid-19; disease; fault
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        item: #1786 of 7819
          id: cord-272154-nrm9ulj5
      author: Gupta, Ravi
       title: Guidelines of the Indian Society for Sleep Research (ISSR) for Practice of Sleep Medicine during COVID-19
        date: 2020-07-04
       words: 5691
      flesch: 53
     summary: As sleep services resume operations, there is a need to find innovative ways to reduce contact with COVID-19 patients, follow personal protection guidelines, as well as social distancing. As sleep services resume operations, there is a need to find innovative ways to reduce contact with COVID-19 patients, travel, follow personal protection guidelines, as well as social distancing to prevent the spread of COVID-19 infection.
    keywords: consultation; covid-19; guidelines; medicine; pandemic; pap; patients; practice; sleep; teleconsultation; therapy; use
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        item: #1787 of 7819
          id: cord-272178-g1mfkrz2
      author: Akoluk, Arda
       title: Pulmonary Embolism in COVID-19 Treated with VA-ECLS and Catheter tPA
        date: 2020-09-03
       words: 1265
      flesch: 32
     summary: We present the first case of a patient with COVID-19 with massive pulmonary embolism treated successfully with systemic thrombolysis, VA-ECLS, and bail out catheter directed thrombolysis. We present the first case of a patient with COVID-19 with massive pulmonary embolism (PE) treated successfully with systemic thrombolysis, VA-ECLS and bail out catheter directed thrombolysis.
    keywords: catheter; covid-19; embolism; pulmonary; thrombolysis
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        item: #1788 of 7819
          id: cord-272195-c4xypzdx
      author: Alahmad, Barrak
       title: COVID-19 stressors on migrant workers in Kuwait: cumulative risk considerations
        date: 2020-07-08
       words: 3283
      flesch: 45
     summary: key: cord-272195-c4xypzdx authors: Alahmad, Barrak; Kurdi, Hussam; Colonna, Kyle; Gasana, Janvier; Agnew, Jacqueline; Fox, Mary A title: COVID-19 stressors on migrant workers in Kuwait: cumulative risk considerations date: 2020-07-08 journal: BMJ Glob Health DOI: 10.1136/bmjgh-2020-002995 sha: doc_id: 272195 cord_uid: c4xypzdx As a marginalised subpopulation, migrant workers often fall short from protection by public policies, they take precarious jobs with unsafe working and living conditions and they grapple with cultural and linguistic barriers. We applied a comprehensive qualitative cumulative risk assessment framework for migrant workers living in Kuwait.
    keywords: community; covid-19; health; kuwait; non; risk; stressors; workers
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        item: #1789 of 7819
          id: cord-272200-wkifto2o
      author: Rubin, G James
       title: Improving adherence to ‘test, trace and isolate’
        date: 2020-09-10
       words: 1797
      flesch: 52
     summary: Relatedly, some evidence from contact tracing for sexually transmitted infections via geosocial networking apps suggests automatic notification may be preferred for casual partners, whereas contact notification for proximal relationships is still preferred. More traditional methods of contact tracing require the index case to recall information about who they have been close to, know their contact details and volunteer that information.
    keywords: contact; people; symptoms; test
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        item: #1790 of 7819
          id: cord-272219-w4lyryr7
      author: Chate, Rodrigo Caruso
       title: Presentation of pulmonary infection on CT in COVID-19: initial experience in Brazil
        date: 2020
       words: 2059
      flesch: 34
     summary: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan American College of Radiology (ACR) VA: ACR; c2020 ACR Recommendations for the use of Chest Radiography and Computed Tomography (CT) for Suspected COVID-19 Infection Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR) Presentation of pulmonary infection on CT in COVID-19: initial experience in Brazil São Paulo: CBR; c2020 Recomendações de uso de métodos de imagem para pacientes suspeitos de infecção pelo COVID-19 Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT Imaging Profile of the COVID-19 Infection: Radiologic Findings and Literature Review CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV) Chest Imaging Appearance of COVID-19 Longitudinal CT Findings in COVID-19 Pneumonia: Multiple articles have been published reporting CT findings in COVID-19, even in patients with negative RT-PCR results, arousing interest in the role of CT in the current clinical scenario.
    keywords: chest; covid-19; findings; patients
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        item: #1791 of 7819
          id: cord-272270-cfpd45qf
      author: Li, H.
       title: Utah-Stanford Ventilator (Vent4US): Developing a rapidlyscalable ventilator for COVID-19 patients with ARDS
        date: 2020-04-22
       words: 3119
      flesch: 47
     summary: e. Ventilation and ventilation control from an oxygen cylinder in settings where compressed medical air is not available. Not only is the number of critical care ventilators limited, even the production capacity of the global medical device industry is insufficient to meet demand [5] .
    keywords: covid-19; flow; license; patient; power; preprint; pressure; system; ventilation; ventilators
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        item: #1792 of 7819
          id: cord-272295-9sonr8or
      author: Lechien, Jerome R.
       title: Objective Olfactory Findings in Hospitalized Severe COVID-19 Patients
        date: 2020-07-31
       words: 1691
      flesch: 44
     summary: Methods: Severe COVID-19 patients with self-reported SLS were recruited at hospitalization discharge. Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): A multicenter European study Smell dysfunction: A biomarker for COVID-19 Objective olfactory evaluation of self-reported loss of smell in a case series of 86 COVID-19 patients Olfactory and gustatory function impairment in COVID-19 patients: Italian objective multicenter-study Loss of Smell and Taste in 2013 European Mild-to-Moderation COVID-19 Patients French adaptation and validation of the sino-nasal outcome test-22: A prospective cohort study on quality of life among 422 subjects Immunology of COVID-19:
    keywords: covid-19; objective; patients; sls
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        item: #1793 of 7819
          id: cord-272300-ck301hcu
      author: Chahrour, Mohamad
       title: A Bibliometric Analysis of COVID-19 Research Activity: A Call for Increased Output
        date: 2020-03-21
       words: 2354
      flesch: 47
     summary: PubMed publications were cross-referenced to the ones found in the WHO spreadsheet on COVID-19 publications. The aim of this paper is to explore the activity and trends of COVID-19 research since its outbreak in December 2019.
    keywords: covid-19; disease; publications; research; studies
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        item: #1794 of 7819
          id: cord-272303-6s0qr4e6
      author: Kriaucioniene, Vilma
       title: Associations between Changes in Health Behaviours and Body Weight during the COVID-19 Quarantine in Lithuania: The Lithuanian COVIDiet Study
        date: 2020-10-13
       words: 3179
      flesch: 52
     summary: The self-administered questionnaire included health behaviour and weight change data. This study aimed to evaluate the effect of the quarantine on dietary, physical activity and alcohol consumption habits of Lithuanians and the association between health behaviours and weight changes.
    keywords: activity; consumption; covid-19; food; gain; quarantine; weight
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        item: #1795 of 7819
          id: cord-272310-imvxrroc
      author: Nyholm, Silvia
       title: Invasive mechanical ventilation in a former preterm infant with COVID‐19
        date: 2020-07-06
       words: 712
      flesch: 53
     summary: imvxrroc The consensus to date is that most infants and children only have mild COVID-19 symptoms and The consensus to date is that most infants and children only have mild COVID-19 symptoms and
    keywords: apnoeas; care; covid-19
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        item: #1796 of 7819
          id: cord-272314-6suu8n75
      author: Hetland, Breanna
       title: 2020 - The Year that Needed the Nurse: Considerations for Critical Care Nursing Research and Practice Emerging in the Midst of COVID-19
        date: 2020-05-03
       words: 1288
      flesch: 34
     summary: The high acuity of ICU patients with COVID-19 coupled with burgeoning unit census brought a common challenge faced by critical care nurses into sharp focus: the extreme difficulty in providing humanistic integrated patient and family centered care to our sickest ICU patients. Critical care nurses are on the frontlines, shouldering the heavy burden of managing the 'sickest of the sick' patients who are in need of life-saving mechanical ventilatory support.
    keywords: care; covid-19; patients; research
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        item: #1797 of 7819
          id: cord-272318-8yfg1j0o
      author: Reddy, Sujan T.
       title: Cerebrovascular Disease in Patients with COVID-19: A Review of the Literature and Case Series
        date: 2020-06-11
       words: 3399
      flesch: 39
     summary: In addition, patients with severe pneumonia (as defined by American Thoracic Society guidelines for community-acquired pneumonia) from COVID-19 infection were also more likely to develop new-onset CVD. Viral neurotropism, endothelial dysfunction, coagulopathy and inflammation are plausible proposed mechanisms of CVD in COVID-19 patients.
    keywords: brain; case; covid-19; cvd; disease; infection; patients; series; stroke
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        item: #1798 of 7819
          id: cord-272349-cqzfjg5t
      author: De Lorenzo, Antonino
       title: Fat mass affects nutritional status of ICU COVID-19 patients
        date: 2020-08-03
       words: 3724
      flesch: 42
     summary: This is the first study evaluating FM% in COVID-19 patient. Despite the relationship between FM% and severity of progression inflammatory response in patients admitted to ICU for underlying infective disease, there are no available data on the relevance of FM% in COVID-19 patients treated in ICU.
    keywords: bmi; body; covid-19; fat; fm%; icu; nutritional; obese; obesity; patients; response
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        item: #1799 of 7819
          id: cord-272395-ygtqbqjf
      author: González-Fernández, Jorge
       title: Gestión de los cadáveres durante la pandemia por COVID-19 en España
        date: 2020-05-11
       words: 5697
      flesch: 33
     summary: key: cord-272395-ygtqbqjf authors: González-Fernández, Jorge; Ibáñez-Bernáldez, María; Amador Martínez-Tejedor, José; Alama-Carrizo, Sergio; Sánchez-Ugena, Félix title: Gestión de los cadáveres durante la pandemia por COVID-19 en España date: 2020-05-11 journal: nan DOI: 10.1016/j.reml.2020.05.001 sha: doc_id: 272395 cord_uid: ygtqbqjf Resumen El brote por el Coronavirus/COVID-19, declarado Emergencia de Salud Pública de Importancia Internacional el 30 de enero de 2020 por la Organización Mundial de la Salud, ha sobrepasado en numerosos países la capacidad de respuesta del sistema sanitario por su alta contagiosidad, y la de gestión de las personas fallecidas por su elevado riesgo de letalidad. El brote por el Coronavirus/COVID-19, declarado Emergencia de Salud Pública de Importancia Internacional el 30 de enero de 2020 por la Organización Mundial de la Salud, ha sobrepasado en numerosos países la capacidad de respuesta del sistema sanitario por su alta contagiosidad, y la de gestión de las personas fallecidas por su elevado riesgo de letalidad.
    keywords: ante; autopsias; cadáveres; casos; como; con; coronavirus; covid-19; crisis; de la; de los; del; durante; en el; entre; forense; gestión; las; los; los cadáveres; medidas; muerte; médico; número; pandemia; para; personas; por; por el; que; riesgo; salud; sanidad; sanitaria; situación; sobre; traslado; una
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        item: #1800 of 7819
          id: cord-272419-y3ebt4jm
      author: Monari, Caterina
       title: A Focus on the Nowadays Potential Antiviral Strategies in Early Phase of Coronavirus Disease 2019 (Covid-19): A Narrative Review
        date: 2020-08-09
       words: 6494
      flesch: 40
     summary: However, currently, there are very few data regarding the efficacy and safety profile of DRV/c in COVID-19 patients. However, a recent paper by Stauffer et al. has highlighted the relevant role that ivermectine may play in COVID-19 patients in preventing Strongyloides hyperinfection, which is a potential fatal complication secondary to the administration of dexamethasone [77] .
    keywords: coronavirus; cov-2; covid-19; efficacy; hcq; infection; lpv; patients; remdesivir; sars; study; treatment; trial
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        item: #1801 of 7819
          id: cord-272426-0bpod47w
      author: GEMCIOGLU, Emin
       title: Are Type 1 Interferons treatment in Multiple Sclerosis as a potential therapy against COVID-19?
        date: 2020-05-16
       words: 1044
      flesch: 49
     summary: There are a few studies about the effect of interferon therapy in COVID-19 patients [1, 2, 3] . As to be parallel with this treatment suggestion and researches, we wanted to present our 31 years old male patient with Multiple Sclerosis (MS) who was under beta interferon treatment since he got the diagnosis approximately for 2 years.
    keywords: covid-19; interferon; treatment
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        item: #1802 of 7819
          id: cord-272427-jqs00ilp
      author: Li, Yu-xuan
       title: The impact of COVID-19 on gastric cancer surgery: a single-center retrospective study
        date: 2020-10-02
       words: 2658
      flesch: 47
     summary: Due to the prevailing pandemic, we propose some surgical strategies for gastric cancer patients. Based on our experiences during the pandemic period, we propose some surgical strategies for gastric cancer patients.
    keywords: cancer; covid-19; hospital; patients; period; surgery
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        item: #1803 of 7819
          id: cord-272444-3qm29srx
      author: Courtney, Alona
       title: CRC COVID: Colorectal Cancer Services during COVID-19 pandemic. Study protocol for service evaluation
        date: 2020-08-11
       words: 2673
      flesch: 46
     summary: The natural history of operable cancer of the alimentary tract Effect of length of time from diagnosis to treatment on colorectal cancer survival: A population-based study Time from diagnosis to treatment of colorectal cancer in a South Australian clinical registry cohort: how it varies and relates to survival Bowel cancer survival statistics Are We Harming Cancer Patients by Delaying Their Cancer Surgery During the COVID-19 Pandemic? � COVID-19 disrupted healthcare provision worldwide � This is a four-phase multi-centre service evaluation of colorectal cancer services � Conducted through a research collaborative in the UK, Ireland and the USA � The aim is to evaluate the impact of the COVID-19 pandemic on service provision The aim of the CRC COVID study is to describe the changes in colorectal cancer services in the UK and USA in response to the pandemic and to understand the long-term impact.
    keywords: cancer; covid-19; data; pandemic; phase; service; study
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        item: #1804 of 7819
          id: cord-272445-0xauff51
      author: Naaber, Paul
       title: Evaluation of SARS-CoV-2 IgG antibody response in PCR positive patients: Comparison of nine tests in relation to clinical data
        date: 2020-10-27
       words: 2752
      flesch: 45
     summary: Given the large variability in antibody tests, discrepancies between test results are expected. We found a remarkable variation in the sensitivity of antibody tests with the following performance: LIPS N (91.8%), Epitope (85.6%), Abbott and in-house LIPS S-RBD (both 84.5%), Roche (83.5%), Euroimmun (82.5%), DiaSorin (81.4%), SNIBE (70.1%), and Biosensor (64.9%).
    keywords: antibody; covid-19; patients; results; tests
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        item: #1805 of 7819
          id: cord-272452-tfj8j9ww
      author: Berger, Jeffrey S.
       title: Prevalence and Outcomes of D-Dimer Elevation in Hospitalized Patients With COVID-19
        date: 2020-08-25
       words: 3375
      flesch: 36
     summary: The present study provides additional support that COVID-19 is a coagulopathic condition with D-dimer representing a direct link between COVID-19 infection and adverse outcomes. Division of General Internal Medicine and Clinical Innovation, Department of Medicine Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) ST-segment elevation in patients with COVID-19 -a case series Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Swaminathan S; COVID-19 and ACE2 in Cardiovascular, Lung, and Kidney Working Group. Among 2377 adults hospitalized with COVID-19 and ≥1 D-dimer measurement, 1823 (76%) had elevated D-dimer at presentation.
    keywords: acute; covid-19; dimer; illness; injury; kidney; patients; risk
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        item: #1806 of 7819
          id: cord-272457-vbqj0bj0
      author: Varikasuvu, Seshadri Reddy
       title: Markers of coagulation dysfunction and inflammation in diabetic and non-diabetic COVID-19
        date: 2020-09-05
       words: 1357
      flesch: 35
     summary: The levels of serum ferritin (standardized mean difference-SMD: 0.47, CI 0.17–0.77, p = 0.002), C-reactive protein (SMD = 0.53, CI 0.20–0.86, p = 0.002), interleukin-6 (SMD = 0.31, CI 0.09–0.52, p = 0.005), fibrinogen (SMD = 0.31, CI 0.09–0.54, p = 0.007) and D-dimers (SMD = 0.54, CI 0.16–0.91, p = 0.005) were significantly higher in diabetic COVID-19 cases as compared to non-diabetic COVID-19 patients, suggesting more susceptibility of diabetic COVID-19 patients to coagulation dysfunction and inflammatory storm. With a significant between-study heterogeneity (I 2 = 64%, p < 0.0001), the random-effects model showed significantly higher levels of inflammatory and hypercoagulability markers in diabetic COVID-19 group when compared to that of non-diabetic COVID-19 group (Fig. 1 ).
    keywords: covid-19; diabetic; patients
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        item: #1807 of 7819
          id: cord-272491-a84pahdr
      author: Maron-Gutierrez, Tatiana
       title: Cell-Free Therapies: Novel Approaches for COVID-19
        date: 2020-09-18
       words: 3336
      flesch: 19
     summary: Mesenchymal stem cells as a potential therapy for COVID-19 Regenerative medicine in COVID-19 treatment : real opportunities and range of promises The involvement of the central nervous system in patients with COVID-19 Multiple organ dysfunction in SARS-CoV-2 : MODS-CoV-2 Rationale for the clinical use of adipose-derived mesenchymal stem cells for COVID-19 patients Can stem cells beat COVID-19: advancing stem cells and extracellular vesicles toward mainstream medicine for lung injuries associated with SARS-CoV-2 infections Emerging therapies for COVID-19 pneumonia Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury Dexamethasone in hospitalized patients with Covid-19 -preliminary report Mesenchymal stem cell therapy for COVID-19: present or future Transplantation of ACE2-mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: review of 3939 COVID-19 patients in China and emerging pathogenesis and therapy concepts CD147 as a target for COVID-19 treatment: suggested effects of azithromycin and stem cell engagement Current status of cell-based therapies for respiratory virus infections: applicability to COVID-19 Emerging trends in COVID-19 treatment: learning from inflammatory conditions associated with cellular therapies Extracellular vesicles : a new frontier for research in acute respiratory Mesenchymal stromal cell secretome for severe COVID-19 infections: premises for the therapeutic use Current understanding of the therapeutic benefits of mesenchymal stem cells in acute respiratory distress syndrome International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 Modulation of the mesenchymal Stem cell secretome using computer-controlled bioreactors: impact on neuronal cell proliferation, survival and differentiation Non-coding RNAs in mesenchymal stem cell-derived extracellular vesicles: deciphering regulatory roles in stem cell potency, inflammatory resolve, and tissue regeneration Bioprocessing of mesenchymal stem cells and their derivatives: toward cell-free therapeutics Exosomes derived from bone marrow mesenchymal stem cells as treatment for severe COVID-19 Cell-based therapies for the acute respiratory distress syndrome Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury Mitochondrial transfer from MSCs to T cells induces treg differentiation and restricts inflammatory response Clinical features of patients infected with 2019 novel coronavirus in Wuhan Molecular mechanisms responsible for therapeutic potential of mesenchymal stem cell-derived secretome Respiratory syncytial virus-infected mesenchymal stem cells regulate immunity via interferon beta and indoleamine-2,3-dioxygenase An energetic view of stress: focus on mitochondria Mitochondria as key components of the stress response The third international consensus definitions for sepsis and septic shock (sepsis-3) Neuroanatomy of sepsis-associated encephalopathy Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs Mitochondria are a subset of extracellular vesicles released by activated monocytes and induce type I IFN and TNF responses in endothelial cells Is a Cytokine storm relevant to COVID-19? Ann Transl Med Extracellular vesicles and matrix remodeling enzymes: the emerging roles in extracellular matrix remodeling, progression of diseases and tissue repair Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines The role of extracellular vesicles in COVID-19 virus infection Current knowledge and future perspectives on mesenchymal stem cell-derived exosomes as a new therapeutic agent Functional proteins of mesenchymal stem cell-derived extracellular vesicles Effects of mesenchymal stem cell therapy on the time course of pulmonary remodeling depend on the etiology of lung injury in mice Identification of the right cell sources for the production of therapeutically active extracellular vesicles in ischemic stroke Human mesenchymal stem cell microvesicles for treatment of Escherichia coli endotoxin-induced acute lung injury in mice Therapeutic effects of human mesenchymal stem cell-derived microvesicles in severe pneumonia in mice Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model Mesenchymal stem cells-derived extracellular vesicles in acute respiratory distress syndrome: a review of current literature and potential future treatment options Exosomes derived from endothelial progenitor cells ameliorate acute lung injury by transferring miR-126 Extracellular vesicles derived from mesenchymal stromal cells: a therapeutic option in respiratory diseases? Mesenchymal stem cell-derived extracellular vesicles decrease lung injury in mice Mesenchymal stromal cell-derived small extracellular vesicles induce ischemic neuroprotection by modulating leukocytes and specifically neutrophils Extracellular vesicles improve post-stroke neuroregeneration and prevent postischemic immunosuppression Exosomes derived from bone marrow mesenchymal stem cells as treatment for severe COVID-19 Clinical cellular therapeutics accelerate clot formation Are therapeutic human mesenchymal stromal cells compatible with human blood?
    keywords: cell; covid-19; evs; mesenchymal; mscs; secretome; stem; therapies; vesicles
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        item: #1808 of 7819
          id: cord-272494-du3y82pq
      author: Abbas, Abdul-Rahman
       title: Today's actions shape tomorrow's world: is the Coronavirus Pandemic (COVID-19) eroding our privacy?
        date: 2020-05-12
       words: 421
      flesch: 46
     summary: 2 Europe and the United States (US) have taken a slightly different approach; European governments are using allegedly anonymised mobile data to trace individuals' movements while the US are using similar data streams obtained from advertising firms to trace the presence of large congregations. 4 However, historical mismanagement of data by such companies has previously resulted in European-Union-sanctioned fines.
    keywords: covid-19; data
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        item: #1809 of 7819
          id: cord-272497-ww9o1kjr
      author: Al-Anzi, Bader S.
       title: An Overview of the World Current and Future Assessment of Novel COVID-19 Trajectory, Impact, and Potential Preventive Strategies at Healthcare Settings
        date: 2020-09-25
       words: 8899
      flesch: 55
     summary: For example, the total predicted total COVID-19 infected cases for Brazil, India, and USA by 15 August is expected to be around 6,000,000, 3,259,917, and 5,800,000 with the number of deaths expected to be equal to 200,000, 60,000, and 1,600,000, respectively. For example, the total predicted total COVID-19 infected cases for Brazil, India, and USA by 15 August is expected to be around 6,000,000, 3,259,917, and 5,800,000 with the number of deaths expected to be equal to 200,000, 60,000, and 1,600,000, respectively.
    keywords: cases; countries; covid-19; group; interval; model; stage; total; world
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        item: #1810 of 7819
          id: cord-272509-os02hlf1
      author: Burns, Graham P
       title: Improved survival following ward-based non-invasive pressure support for severe hypoxia in a cohort of frail patients with COVID-19: retrospective analysis from a UK teaching hospital
        date: 2020-07-05
       words: 1911
      flesch: 47
     summary: In a substantial number of patients, adequate arterial oxygenation cannot be achieved with supplementary oxygen therapy alone. In a substantial number of patients, adequate arterial oxygenation cannot be achieved with supplemental oxygen alone.
    keywords: covid-19; nips; oxygen; patients; ventilation
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        item: #1811 of 7819
          id: cord-272537-ivqmw0dy
      author: Smilowitz, Nathaniel R.
       title: Thrombosis in Hospitalized Patients with Viral Respiratory Infections versus COVID-19
        date: 2020-11-10
       words: 849
      flesch: 27
     summary: (2) Previous estimates of in-hospital thrombotic risk are based on small series of patients with influenza.(3) Alveolar capillary microthrombi are 9 times as prevalent at autopsy in COVID-19 than in influenza, but there are limited data comparing rates of thrombosis in COVID-19 to non-COVID-19 respiratory viral illnesses.(4) We set out to evaluate the incidence of arterial and venous thrombosis in a cohort of patients hospitalized with non-COVID-19 acute viral respiratory illnesses compared to COVID-19. We evaluated the incidence of thrombosis in patients hospitalized with non-COVID-19 acute viral respiratory illnesses compared to COVID-19.
    keywords: covid-19; thrombosis
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        item: #1812 of 7819
          id: cord-272546-zznm13ik
      author: Van den Eynde, Jef
       title: Cardiothoracic robotic assisted surgery in times of COVID-19
        date: 2020-05-08
       words: 1876
      flesch: 34
     summary: Importantly, cardiothoracic RAS may require one-lung ventilation to create more space within the thoracic cavity, hence providing adequate visualization during robotic surgery. At a time when elective surgeries are being suspended and questions are being raised about how the remaining procedures on COVID-19 positive patients can be performed safely, it is important to consider the potential role of robotic assisted surgery within the current pandemic.
    keywords: covid-19; lung; patients; surgery; use
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        item: #1813 of 7819
          id: cord-272553-bcmta2he
      author: Wang, Zhiqiang
       title: Clinical characteristics and laboratory results of pregnant women with COVID‐19 in Wuhan, China
        date: 2020-07-03
       words: 1666
      flesch: 39
     summary: 8, 9 This may be one reason that the pandemic spread so quickly at The present study also found that the typical symptoms of COVID-19 may have been milder in pregnant patients than in nonpregnant patients, which was also reported in an earlier study. The WHO-report on the COVID-19 outbreak in China What are the risks of COVID-19 infection in pregnant women? Management of pregnant women infected with COVID-19 COVID-19 in pregnant women Detection and analysis of nucleic acid in various biological samples of COVID-19 patients The role of chest imaging in patient management during the COVID-19 pandemic: A multinational consensus statement from the Fleischner Society The 5th edition of diagnosis and treatment program of COVID-19 pneumonia from the National Health Commission Coronavirus infections-more than just the common cold A new coronavirus associated with human respiratory disease in China Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing COVID-19: What is next for public health? Clinical Characteristics of Pregnant Women with Covid-19 in Wuhan, China Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: A retrospective review of medical records Expert consensus for managing pregnant women and neonates born to mothers with suspected or confirmed novel coronavirus (COVID-19) infection Characteristics of peripheral blood leukocyte differential counts in patients with COVID-19 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study Procalcitonin-guided antibiotic therapy in patients with fever in a general emergency department population: A multicentre non-inferiority randomized clinical trial (HiTEMP study) Diagnostic utility of clinical laboratory data determinations for patients with the severe COVID-19 Chest CT manifestations of new coronavirus disease 2019 (COVID-19): A pictorial review
    keywords: covid-19; patients; results; study
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        item: #1814 of 7819
          id: cord-272566-rtnhndw3
      author: Robertson, M.
       title: A national prospective cohort study of SARS/COV2 pandemic outcomes in the U.S.: The CHASING COVID Cohort
        date: 2020-05-04
       words: 5164
      flesch: 50
     summary: Following baseline questionnaire completion, study participants will be contacted monthly (for 6 months) to complete assessments of engagement in non-pharmaceutical interventions (e.g., use of cloth masks, avoiding large gatherings); COVID-19 symptoms; SARS/COV2 testing and diagnosis; hospitalizations; healthcare access; and uptake of health messaging. Study participants were recruited via social media platforms (e.g., Facebook, Instagram, and Scruff) or via referral to the study.
    keywords: cov2; covid-19; funder; license; medrxiv; participants; perpetuity; preprint; sars; study; version
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        item: #1815 of 7819
          id: cord-272573-wxqly479
      author: Maia Chagas, Andre
       title: Leveraging open hardware to alleviate the burden of COVID-19 on global health systems
        date: 2020-04-24
       words: 5088
      flesch: 48
     summary: Most of the technology discussed above is classed as a medical device when used in a diagnostic or clinical setting; a challenge faced by only a small number of existing open hardware devices and therefore in need of further research. [Internet Return on investment for open source scientific hardware development How poorer countries are scrambling to prevent a coronavirus disaster 3D printing and milling a real-time PCR device for infectious disease diagnostics A Customized Bolus Produced Using a 3-Dimensional Printer for Radiotherapy A low-cost and small USV platform for water quality monitoring A Portable 3D Printer System for the Diagnosis and Treatment of Multidrug-Resistant Bacteria A versatile and low-cost open source pipetting robot for automation of toxicological and ecotoxicological bioassays Smart Citizen Kit and Station: An open environmental monitoring system for citizen participation and scientific experimentation PlasmoTron: an open-source platform for automated culture of malaria parasites Open(G)PIAS: An Open-Source Solution for the Construction of a High-Precision Acoustic Startle Response Setup for Tinnitus Screening and Threshold Estimation in Rodents Open-source automated external defibrillator RSG Safety-EN Standards & Approvals European standards for medical supplies freely available.
    keywords: community; coronavirus; cov-2; covid-19; detection; example; fosh; hardware; masks; rna; sars; source; testing; use; ventilators
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        item: #1816 of 7819
          id: cord-272585-346ef6qy
      author: Lombardi, JM
       title: Addressing a National Crisis: The Spine Hospital and Department's Response to the COVID-19 Pandemic in New York City
        date: 2020-05-31
       words: 5081
      flesch: 47
     summary: To date, our hospital has treated thousands of COVID-19 positive patients and sits at the forefront of the United States response to this pandemic. Published data by healthcare providers in Asia and Europe demonstrated that the most substantial threat to COVID-19 patient morbidity and mortality was the lack of adequate critical care resources including intensive care unit (ICU) beds and respiratory support [8] [9] .
    keywords: care; cases; covid-19; department; health; hospital; new; operating; pandemic; patients; room; spine
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        item: #1817 of 7819
          id: cord-272600-0uklma5w
      author: Loi, Kim Ieng
       title: Understanding the reactions of government and gaming concessionaires on COVID-19 through the neo-institutional theory – The case of Macao
        date: 2020-11-02
       words: 8931
      flesch: 44
     summary: The first case of Novel Coronavirus confirmed in Macao SAR, marking the first wave of confirmed cases (a) . Group tour visas for Mainland Chinese to Macao SAR suspended (b) .
    keywords: business; case; covid-19; gaming; government; hospitality; hotel; industry; legitimacy; macao; management; organisations; pandemic; participants; staff; time; tourism
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        item: #1818 of 7819
          id: cord-272630-2na1gndu
      author: Benito, Daniel A.
       title: Local spikes in COVID-19 cases: Recommendations for maintaining otolaryngology clinic operations
        date: 2020-08-20
       words: 2089
      flesch: 37
     summary: key: cord-272630-2na1gndu authors: Benito, Daniel A.; Pasick, Luke; Mulcahy, Collin F.; Rajasekaran, Karthik; Todd-Hesham, Hosai; Joshi, Arjun S.; Goodman, Joseph F.; Thakkar, Punam title: Local spikes in COVID-19 cases: Recommendations for maintaining otolaryngology clinic operations date: 2020-08-20 journal: Am J Otolaryngol DOI: 10.1016/j.amjoto.2020.102688 sha: doc_id: 272630 cord_uid: 2na1gndu The Coronavirus Disease-2019 (COVID-19) pandemic has created an unprecedented economic and public health crisis in the United States. As otolaryngologists prepare to weather the storm of impending local surges in COVID-19 infections there are several practical measures that can be taken to mitigate the risk to ourselves and our staff.
    keywords: covid-19; otolaryngology; patients; procedures; recommendations; staff
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        item: #1819 of 7819
          id: cord-272654-hh29olk7
      author: Bošnjak, Berislav
       title: Low serum neutralizing anti-SARS-CoV-2 S antibody levels in mildly affected COVID-19 convalescent patients revealed by two different detection methods
        date: 2020-11-02
       words: 6125
      flesch: 44
     summary: Positive correlation between total anti-S1 protein and neutralizing antibody levels in sera of convalescent individuals with mild COVID- 19 We then analyzed the correlation between total levels of anti-S1 IgG and IgA and the amount of neutralizing antibodies in our cohort of mild COVID-19 convalescent patients and healthy controls. Combining pVNT and sVNT, we found that~90% of recovered patients with mild COVID-19 possessed neutralizing serum antibodies.
    keywords: antibodies; antibody; convalescent; cov-2; covid-19; fig; igg; levels; patients; sars; svnt
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        item: #1820 of 7819
          id: cord-272681-u3p0hsla
      author: Vargas-Gandica, Jair
       title: Ageusia and anosmia, a common sign of COVID-19? A case series from four countries
        date: 2020-07-14
       words: 1513
      flesch: 40
     summary: Recent data suggest that smell and taste disorders may be significantly more frequent among COVID-19 patients than influenza patients (Hopkins et al. 2020; Lechner et al. 2020; Lee et al. 2020; Moein et al. 2020; Reinhard et al. 2020; Tong et al. 2020 ). Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis Tracing new clinical manifestations in patients with COVID-19 in Chile and its potential relationship with the SARS-CoV-2 divergence Postviral olfactory loss The prevalence of olfactory and gustatory dysfunction in COVID-19 patients: a systematic review and meta-analysis The olfactory nerve: a shortcut for influenza and other viral diseases into the central nervous system Guillain-Barre syndrome associated with SARS-CoV-2 infection: causality or coincidence? Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
    keywords: covid-19; patients
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        item: #1821 of 7819
          id: cord-272715-33c85eaa
      author: Ma, R. C. W.
       title: COVID‐19 and diabetes
        date: 2020-04-03
       words: 1244
      flesch: 42
     summary: Real estimates of mortality following COVID-19 infection Secular trends in all-cause and cause-specific mortality rates in people with diabetes in Hong Kong Clinical Characteristics of Coronavirus Disease 2019 in China Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Angiotensinconverting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target Angiotensinconverting enzyme 2 protects from severe acute lung failure Position Statement of the ESC Council on Hypertension on ACE-Inhibitors and Angiotensin Receptor Blockers. It is currently unknown why people with diabetes, hypertension or other chronic diseases are more severely affected by COVID-19, but one possible explanation involves angiotensin-converting enzyme 2 (ACE2).
    keywords: covid-19; diabetes; disease; people
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        item: #1822 of 7819
          id: cord-272720-isqc0bv8
      author: Keil, Evan J.
       title: Social Media Perceptions of Surgical Cancer Care in the Era of COVID-19: A Global Cross-Sectional Study
        date: 2020-08-14
       words: 3010
      flesch: 44
     summary: While data have been published in survey form on the basis of an evaluation of the impact to cancer surgery from the perspective of surgical oncologists, there is a need to evaluate the impact on and perspectives of the wider surgical cancer community. There was an overwhelming perception that cancer surgery is essential and a focus on the cancellations, rescheduling, and need for education with regard to best practices within cancer care during the global pandemic.
    keywords: cancer; care; covid-19; media; patients; posts
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        item: #1823 of 7819
          id: cord-272726-ljjirt4g
      author: Brethauer, Stacy A.
       title: Redesigning a Department of Surgery during the COVID-19 Pandemic
        date: 2020-04-28
       words: 3556
      flesch: 45
     summary: A call for volunteers to cover the ICU, trauma, or acute care surgery services was sent to faculty members outside the division covering trauma and acute care surgery and the surgical intensive care units. For services still performing some essential operations (e.g., advanced cancer, emergent cardiac, trauma, or acute care surgery), every effort was made to minimize the number of faculty coming to work with coverage provided by those who were coming in for operative cases or on call.
    keywords: care; cases; covid-19; crisis; department; faculty; health; patients; surgery; system
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        item: #1824 of 7819
          id: cord-272727-a5ngjuyz
      author: Bertsimas, D.
       title: From predictions to prescriptions: A data-drivenresponse to COVID-19
        date: 2020-06-29
       words: 3599
      flesch: 47
     summary: We have 206 therefore initiated a multi-institution collaboration to collect 207 electronic medical records from COVID-19 patients and de-208 velop clinical risk calculators. Once the 223 burden on hot spots has ebbed, hospitals began to aggregate 224 rich data on COVID-19 patients.
    keywords: covid-19; data; disease; infection; model; mortality; pandemic; patients; policies; risk
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        item: #1825 of 7819
          id: cord-272737-m05f4eml
      author: Ko, Jane P.
       title: Pulmonary COVID-19: Multimodality Imaging Examples
        date: 2020-10-09
       words: 727
      flesch: 39
     summary: COVID-19 imaging findings at chest radiography correlate with chest CT findings. Acute pulmonary embolism associated with COVID-19 pneumonia detected with pulmonary CT angiography Pulmonary embolism on CTPA in COVID-19 patients Diagnostic performance of CT and reverse transcriptase polymerase chain reaction for coronavirus disease 2019: a meta-analysis CO-RADS: a categorical CT assessment scheme for patients with suspected COVID-19-definition and evaluation The role of chest imaging in patient management during the COVID-19 pandemic: a multinational consensus statement from the Fleischner Society Radiological Society of North America expert consensus statement on reporting chest CT findings related to COVID-19.
    keywords: chest; covid-19; imaging
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        item: #1826 of 7819
          id: cord-272757-pyl89jqk
      author: Sarhan, A. R.
       title: Novel coronavirus (COVID-19) Outbreak in Iraq: The First Wave and Future Scenario
        date: 2020-06-26
       words: 2941
      flesch: 62
     summary: Over the past few months there has been a significant increase in COVID-19 cases. It's worth notice that the total cumulative number of COVID-19 cases increasing significantly, so this is could be a sign that a country will faces a second wave of virus infections.
    keywords: cases; coronavirus; covid-19; figure; iraq; patients
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        item: #1827 of 7819
          id: cord-272772-zqmychmr
      author: Stall, Nathan M.
       title: Finding the Right Balance: An Evidence-Informed Guidance Document to Support the Re-Opening of Canadian Nursing Homes to Family Caregivers and Visitors during the COVID-19 Pandemic
        date: 2020-08-03
       words: 4442
      flesch: 43
     summary: Whereas equality would mean giving all nursing home 171 residents the same access to visitors, equity means giving nursing home residents the right 172 amount of access they need to maintain their health and wellbeing. Appendix 1: Nursing home visitor policies for Canada's ten provinces and three territories (as of July 14, 2020) 6 .
    keywords: caregivers; covid-19; family; homes; nursing; residents; support; visitors
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        item: #1828 of 7819
          id: cord-272778-aixiioii
      author: Chen, Qingqing
       title: Clinical characteristics of 145 patients with corona virus disease 2019 (COVID-19) in Taizhou, Zhejiang, China
        date: 2020-04-28
       words: 3027
      flesch: 49
     summary: CONCLUSIONS: Older patients or patients with comorbidities such as obesity or diabetes mellitus were more likely to have severe condition. Older patients or patients with comorbidities such as obesity or diabetes mellitus were more likely to have severe condition.
    keywords: china; clinical; covid-19; patients; pneumonia; study; taizhou
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        item: #1829 of 7819
          id: cord-272796-7br822q3
      author: Shang, Luxiang
       title: Diabetes Mellitus is Associated with Severe Infection and Mortality in Patients with COVID-19: A Systematic Review and Meta-analysis
        date: 2020-08-07
       words: 2743
      flesch: 27
     summary: COVID-19 patients with DM had higher mortality rate compared with those non-diabetic patients The sensitivity analysis showed that none of the studies remarkably affected the pooled ORs and CIs Our results showed that diabetic patients with COVID-19 had higher severe infection and case-fatality rates compared with non-diabetic patients, and DM was associated with an increased risk of severe infection and mortality in patients with COVID-19. The primary outcome was to compare the severe infection rate and mortality rate in COVID-19 patients with and without DM, and to calculate the odds ratio (OR) and 95% confidence interval (CI).
    keywords: characteristics; coronavirus; covid-19; disease; patients
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        item: #1830 of 7819
          id: cord-272828-13i2y9kc
      author: Bagheri, Seyed Hamidreza
       title: Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak in Iran
        date: 2020-06-15
       words: 2410
      flesch: 42
     summary: A sudden onset of olfactory dysfunction was reported in 76.24% of the participations and persistent anosmia in 60.90% from the start of COVID19 epidemic. Conclusion: An outbreak of olfactory dysfunction occurred in Iran during the COVID-19 epidemic.
    keywords: anosmia; covid-19; dysfunction; iran; olfactory; study
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        item: #1831 of 7819
          id: cord-272843-fis10xbi
      author: Chowdhury, Rajiv
       title: Cardiometabolic Health: Key in Reducing Adverse COVID-19 Outcomes
        date: 2020-08-19
       words: 2559
      flesch: 35
     summary: While being conscious of implementation challenges, proposed actions provide guidance on health behaviours improving immune and cardiorespiratory function that may reduce adverse COVID-19 outcomes. Finally, inequalities in economic, cultural, and social resources my shape inequalities in abilities to adapt health behaviours, having potential to exacerbate health inequalities [44] .
    keywords: covid-19; disease; health; immune; outcomes; risk; sleep; stress
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        item: #1832 of 7819
          id: cord-272846-pkhu2zvt
      author: Capasso Palamim, Camila Vantini
       title: COVID-19 – four million cases worldwide and the importance of multidisciplinary health care team during the pandemic
        date: 2020-06-10
       words: 390
      flesch: 52
     summary: key: cord-272846-pkhu2zvt authors: Capasso Palamim, Camila Vantini; Lima Marson, Fernando Augusto title: COVID-19 – four million cases worldwide and the importance of multidisciplinary health care team during the pandemic date: 2020-06-10 journal: J Emerg Nurs DOI: 10.1016/j.jen.2020.06.004 sha: doc_id: 272846 cord_uid: pkhu2zvt On 12(th) Multidisciplinary health care team are responsible to keep the patient breath mainly in severe 72 cases of COVID-19 including millions of people worldwide.
    keywords: health
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        item: #1833 of 7819
          id: cord-272872-w592wmvr
      author: Banerjee, Sourav
       title: A Preliminary Report of COVID-19 in Children in India
        date: 2020-07-28
       words: 1013
      flesch: 52
     summary: key: cord-272872-w592wmvr authors: Banerjee, Sourav; Guha, Aritra; Das, Avishikta; Nandi, Mousami; Mondal, Rakesh title: A Preliminary Report of COVID-19 in Children in India date: 2020-07-28 journal: Indian Pediatr DOI: 10.1007/s13312-020-2004-6 sha: doc_id: 272872 cord_uid: w592wmvr We describe the profile of COVID-19 in children from India in this multicentre observational study from tertiary care hospitals in West Bengal. Data of children up to 12 years presenting with positive results on SARS-CoV-2 RT-PCR test were included.
    keywords: children; covid-19; patients
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        item: #1834 of 7819
          id: cord-272909-n6wfe1of
      author: Peng, Shu
       title: Clinical course of coronavirus disease 2019 in 11 patients after thoracic surgery and challenges in diagnosis
        date: 2020-04-10
       words: 3681
      flesch: 41
     summary: In addition, after thoracic surgery patients may also have cough, dyspnea, reactive fever, and postoperative radiologic changes. The overlap between symptoms of COVID-19 and the usual thoracic postoperative clinical course may result in delayed diagnosis: fever and cough from reactive pleural effusion and atelectasis are common after thoracic surgery 8 ; dyspnea may be secondary to lung resection and chronic obstructive lung disease; many thoracic postoperative patients suffer chest tightness and fatigue, loss of appetite, and nausea due to postoperative analgesics; and antibiotics are usually self-limiting.
    keywords: case; covid-19; days; patients; surgery; thoracic
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        item: #1835 of 7819
          id: cord-272916-q8zjrodm
      author: Arasteh, Peyman
       title: A surge in methanol poisoning amid COVID-19 pandemic: why is this occurring?
        date: 2020-05-20
       words: 554
      flesch: 42
     summary: As a result alcohol drinks are perhaps being spiked or, in other words, bootleg alcohol (using methanol) is being produced and used in some regions. Finally, Increased unstructured leisure time, decreased sports activity due to closure of gyms and the mass advertisement to the public to remain home, have all led to increased use of alcohol drinks 3, 4 and this has added more difficulty to the fight against the COVID-19 issue in our region.
    keywords: alcohol; covid-19
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        item: #1836 of 7819
          id: cord-272933-b2phq37e
      author: Alonso Tabares, Diego
       title: An airport operations proposal for a pandemic-free air travel
        date: 2020-10-08
       words: 6829
      flesch: 49
     summary: It is very likely that health aspects may need to be considered from now on by the aviation ecosystem and this may include airport health screening and permanent presence of health personnel at the airport. The potential location of passenger health screening, facilitation requirements, health responsibilities delegation and appropriate usage of industry standards for regulations are key elements to a potential implementation that would be phased and long term.
    keywords: airport; aviation; covid-19; detection; disease; health; measures; pandemic; passenger; public; risk; screening; security; symptoms; test; travel
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        item: #1837 of 7819
          id: cord-272958-0jw75vsm
      author: Liu, Ai-Ling
       title: COVID-19 with asthma: A case report
        date: 2020-08-06
       words: 2185
      flesch: 52
     summary: In December 2019, a cluster of acute respiratory illnesses, now known as coronavirus disease 2019 , occurred in Wuhan, Hubei Province, China It took 41 d from disease onset to discharge to obtain two negative tests for this coronavirus.
    keywords: count; covid-19; disease; patients; treatment
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        item: #1838 of 7819
          id: cord-272961-z0pbah73
      author: Zhang, Jie
       title: Relationship of chest CT score with clinical characteristics of 108 patients hospitalized with COVID-19 in Wuhan, China
        date: 2020-07-14
       words: 3538
      flesch: 46
     summary: Analyze COVID-19 patients to determine the relationships of clinical characteristics, chest CT score, and levels of inflammatory mediators. The relationships between chest CT score with levels of systemic inflammatory mediators were determined.
    keywords: chest; covid-19; lung; patients; pneumonia; score; treatment
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        item: #1839 of 7819
          id: cord-272975-gzsd4ybt
      author: Antony, Arun
       title: Systematic review of EEG findings in 617 patients diagnosed with COVID-19
        date: 2020-10-19
       words: 3558
      flesch: 38
     summary: However, a large study of 111 patients reported that EEG studies were performed after a median of 10.8 days after hospitalization. key: cord-272975-gzsd4ybt authors: Antony, Arun; Haneef, Zulfi title: Systematic review of EEG findings in 617 patients diagnosed with COVID-19 date: 2020-10-19 journal: Seizure DOI: 10.1016/j.seizure.2020.10.014 sha: doc_id: 272975 cord_uid: gzsd4ybt Objective We performed a systematic review of the literature to synthesize the data on EEG findings in COVID-19.
    keywords: covid-19; eeg; findings; patients; studies
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        item: #1840 of 7819
          id: cord-272989-14exeaud
      author: Dawoud, Dalia
       title: Pharmacy practice research priorities during the COVID-19 pandemic: Recommendations of a panel of experts convened by FIP Pharmacy Practice Research Special Interest Group
        date: 2020-08-26
       words: 2361
      flesch: 42
     summary: A panel of leading journal editors was convened by the International Pharmaceutical Federation (FIP) Pharmacy Practice Research Special Interest Group to discuss the current status of COVID-19 related research, provide their recommendations, and identify focal points for pharmacy practice, social pharmacy, and education research moving forward. Res Social Adm Pharm Pandemic preparedness of community pharmacists for COVID-19 Key measures for a successful COVID-19 lockdown exit strategy and the potential contribution of pharmacists Provision of community pharmacy services during COVID-19 pandemic: a cross sectional study of community pharmacists' experiences with preventative measures and sources of information Resilience in the time of the pandemic: The experience of community pharmacists during COVID-19.
    keywords: covid-19; pandemic; pharmacists; pharmacy; practice; research; social
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        item: #1841 of 7819
          id: cord-272995-yvj2pqh1
      author: Bergman, Christian
       title: Recommendations for Welcoming Back Nursing Home Visitors during the COVID-19 Pandemic: Results of a Delphi Panel
        date: 2020-10-07
       words: 6341
      flesch: 46
     summary: J o u r n a l P r e -p r o o f Visitor Guidance for America's Nursing Homes (68%) that residents should be allowed to opt out of testing for sole purposes of surveillance, 116 fewer agreed that testing of asymptomatic residents should not be done (53%). A new or returning asymptomatic nursing home resident without a prior diagnosis of COVID-19 and who has remained under isolation in a private room for 14 days since admission tests positive during nursing home testing of asymptomatic residents.
    keywords: asymptomatic; covid-19; facility; home; nursing; resident; staff; statements; testing
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        item: #1842 of 7819
          id: cord-273005-kab6f157
      author: Longhurst, Georga J.
       title: Strength, Weakness, Opportunity, Threat (SWOT) Analysis of the Adaptations to Anatomical Education in the United Kingdom and Republic of Ireland in Response to the Covid‐19 Pandemic
        date: 2020-05-09
       words: 7775
      flesch: 37
     summary: A novel coronavirus from patients with pneumonia in China Daily medical education for confined students during COVID-19 pandemic: A simple videoconference solution Advice from Medical Schools Council to UK Medical Schools on Actions Surrounding Covid-19 Nursing student's evaluation of a virtual classroom experience in support of their learning bioscience SARS and its effect on medical education in Hong Kong Using videoclips to improve theoretical anatomy teaching Effectiveness of using blended learning strategies for teaching and learning human anatomy Guidance: Staying at home and away from others (social distancing) Sense of connection, identity and academic success in distance education: Sociologically exploring online learning environments Student perceptions of the use of instructor-made videos in online and face-to-face classes Medical student education in the time of COVID-19 RTÉ. THOMAS Acland's Video Atlas of Human Anatomy ® COVID-19 and medical education Lancet Inf Dis The perception of anatomy teaching among UK medical students Second-year medical students' motivational beliefs, emotions, and achievement Improving online interactions.
    keywords: academic; anatomy; assessment; cadaveric; covid-19; education; institutions; learning; medical; new; online; resources; students; teaching; universities
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        item: #1843 of 7819
          id: cord-273017-9yni18cl
      author: Lau, Lincoln Leehang
       title: COVID-19 response strategies: considering inequalities between and within countries
        date: 2020-08-12
       words: 1411
      flesch: 42
     summary: However, given persisting resource limitations, many tuberculosis (TB) testing facilities have been reconfigured for COVID-19 testing in order to meet demands [11] . We have highlighted the observed and anticipated disparities in COVID-19 testing, but other aspects of COVID-19 responses also warrant further exploration.
    keywords: countries; covid-19; philippines; testing
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        item: #1844 of 7819
          id: cord-273022-r2rz2onv
      author: Primov-Fever, Adi
       title: Songbirds Must Sing: How Artistic Voice Users Perceive Their Voice in Times of COVID-19
        date: 2020-08-18
       words: 2842
      flesch: 53
     summary: Professional artistic voice users experience the COVID-19 pandemic as a stressful time, with negative effects on their well-being and specifically on their voice. The survey was distributed to professional artistic voice users through local singers and actors associations, as well as through voice teachers and coaches, and by addressing voice or singing students in local contemporary and classical music training programs.
    keywords: singers; stress; study; users; voice
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        item: #1845 of 7819
          id: cord-273036-nrc35akc
      author: Zou, Xiaojing
       title: Acute Physiology and Chronic Health Evaluation II Score as a Predictor of Hospital Mortality in Patients of Coronavirus Disease 2019
        date: 2020-05-11
       words: 3683
      flesch: 49
     summary: key: cord-273036-nrc35akc authors: Zou, Xiaojing; Li, Shusheng; Fang, Minghao; Hu, Ming; Bian, Yi; Ling, Jianmin; Yu, Shanshan; Jing, Liang; Li, Donghui; Huang, Jiao title: Acute Physiology and Chronic Health Evaluation II Score as a Predictor of Hospital Mortality in Patients of Coronavirus Disease 2019 date: 2020-05-11 journal: Crit Care Med DOI: 10.1097/ccm.0000000000004411 sha: doc_id: 273036 cord_uid: nrc35akc OBJECTIVES: We aimed to assess the association between Acute Physiology and Chronic Health Evaluation II score and hospital mortality in patients with coronavirus disease 2019, and to compare the predictive ability of Acute Physiology and Chronic Health Evaluation II score, with Sequential Organ Failure Assessment score and Confusion, Urea, Respiratory rate, Blood pressure, Age 65 (CURB65) score.
    keywords: acute; covid-19; health; mortality; patients; score
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        item: #1846 of 7819
          id: cord-273044-ikk9d6wz
      author: Knio, Ziyad O
       title: Heated Air Delivery by Micro-Sauna: An Experimental Treatment Prototype Concept for Coronavirus Disease 2019
        date: 2020-05-16
       words: 1893
      flesch: 42
     summary: Heat has been shown to destabilize other coronavirus strains in testing environments, and it has been hypothesized that heated air may destabilize viral pathogens in vivo as well. The present report describes the engineering of a micro-sauna prototype for the delivery of heated air.
    keywords: air; coronavirus; covid-19; degrees; micro; prototype
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        item: #1847 of 7819
          id: cord-273045-ele1cz86
      author: Johnson, Claire D.
       title: Response of Practicing Chiropractors during the Early Phase of the COVID-19 Pandemic: A Descriptive Report
        date: 2020-06-13
       words: 13970
      flesch: 52
     summary: For the chiropractors who practiced in solo practice, they assumed responsibility for the function of the office, including patient care, communications, and sanitation. 125 Health workers initially were only allowed to work if they worked with concerns related to COVID-19 patients.
    keywords: care; chiropractic; chiropractors; clinic; coronavirus; covid-19; government; health; health care; home; information; march; office; pandemic; patients; practice; public; regulations; services; staff; state; telehealth; time; treatment; visits
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        item: #1848 of 7819
          id: cord-273050-reez33md
      author: Wang, Zhenling
       title: Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients
        date: 2020-09-14
       words: 1338
      flesch: 42
     summary: These findings provide insights into the treatment of severe COVID-19 patients with type I IFN. Fig. 1 Immunological characteristics of severe COVID-19 patients.
    keywords: covid-19; ifn; patients; type
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        item: #1849 of 7819
          id: cord-273093-u79r80ip
      author: Laforge, Mireille
       title: Tissue damage from neutrophil-induced oxidative stress in COVID-19
        date: 2020-07-29
       words: 1350
      flesch: 27
     summary: ROS induce tissue damage, thrombosis and red blood cell dysfunction, which contribute to COVID-19 disease severity. ROS induce tissue damage, thrombosis and red blood cell dysfunction, which contribute to COVID-19 disease severity.
    keywords: covid-19; neutrophil; patients; ros
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        item: #1850 of 7819
          id: cord-273114-eanwxkvt
      author: Perrone, Serafina
       title: Report of a series of healthy term newborns from convalescent mothers with COVID-19
        date: 2020-05-11
       words: 1670
      flesch: 49
     summary: CONCLUSIONS: Findings from our series of cases indicated that adverse effects on foetuses from pregnancies complicated by COVID-19 infection in late pregnancy are unlikely. Another report of 10 babies born to mothers with COVID-19 infection described one death in a baby born at 34+5 weeks, however none of the babies tested were positive for SARS-CoV-2 (4).
    keywords: covid-19; infection; pregnancy; sars
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        item: #1851 of 7819
          id: cord-273138-bjm7v26f
      author: Tao, Pei-Yao
       title: Determination of risk factors for predicting the onset of symptoms in asymptomatic COVID-19 infected patients
        date: 2020-08-06
       words: 3328
      flesch: 40
     summary: Indeed, the chest CT imaging is important for screening asymptomatic COVID-19 patients and aiding quarantine and infection control strategies. History of smoking and pulmonary disease was prone to illness onset in asymptomatic patients, and it is necessary to be highly vigilant to those patients.
    keywords: asymptomatic; covid-19; disease; onset; patients; study; symptoms
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        item: #1852 of 7819
          id: cord-273150-bz617ovx
      author: John, Teny M.
       title: Migratory Pulmonary Infiltrates in a Patient with COVID-19 Infection and the Role of Corticosteroids
        date: 2020-06-24
       words: 823
      flesch: 40
     summary: Case Presenting Organizing Pneumonia Pattern John 6 Time to consider histologic pattern of lung injury to treat critically ill patients with COVID-19 infection COVID-19 and Convalescent Plasma: Frequently Asked Questions The BTK-inhibitor ibrutinib may protect against pulmonary injury in COVID-19 infected patients Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Figure legend: Figure 1: Axial CT chest images on day 7 (day of admission, Panel A) and day 17 after symptom onset (Panel B), showing new and migratory lung infiltrates suggestive of organizing pneumonia Summary of a Report of 72314 Cases from the Chinese Center for Disease Control and Prevention Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Longitudinal CT Findings in COVID-19 Pneumonia:
    keywords: covid-19; day; patient; pneumonia
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        item: #1853 of 7819
          id: cord-273175-bao8xxe2
      author: Tran, Viet-Thi
       title: COVID-19–related perceptions, context and attitudes of adults with chronic conditions: Results from a cross-sectional survey nested in the ComPaRe e-cohort
        date: 2020-08-06
       words: 3862
      flesch: 45
     summary: About one quarter of patients would refuse any contact with symptomatic people (17.8% and 23.4% for occasional and COVID-19-related perceptions, context and attitudes of adults with chronic conditions frequent contacts, respectively). key: cord-273175-bao8xxe2 authors: Tran, Viet-Thi; Ravaud, Philippe title: COVID-19–related perceptions, context and attitudes of adults with chronic conditions: Results from a cross-sectional survey nested in the ComPaRe e-cohort date: 2020-08-06 journal: PLoS One DOI: 10.1371/journal.pone.0237296 sha: doc_id: 273175 cord_uid: bao8xxe2 BACKGROUND: To avoid a surge of demand on the healthcare system due to the COVID-19 pandemic, we must reduce transmission to individuals with chronic conditions who are at risk of severe illness with COVID-19.
    keywords: chronic; conditions; contacts; covid-19; participants; patients; people; risk
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        item: #1854 of 7819
          id: cord-273176-7z6e5jhh
      author: Agarwal, A.
       title: Convalescent plasma in the management of moderate COVID-19 in India: An open-label parallel-arm phase II multicentre randomized controlled trial (PLACID Trial)
        date: 2020-09-08
       words: 5592
      flesch: 46
     summary: The primary outcome was not different between the subgroups of intervention arm patients receiving CP with detectable NAb titres (n=160) or CP with NAb titre ≥1:80 (n=68) or CP with no detectable NAbs (n=64) and the control arm ( The PLACID trial results indicate that there was no difference in 28-day mortality or progression to severe disease among moderately ill COVID-19 patients treated with CP along with BSC All rights reserved. Other immune pathways such as antibody-dependent cellular cytotoxicity, complement activation, or phagocytosis are putative mechanisms through which CP may exert its therapeutic effect in COVID-19 patients.
    keywords: arm; covid-19; days; enrolment; intervention; participants; patients; plasma; preprint; trial
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        item: #1855 of 7819
          id: cord-273200-hoqpkdqo
      author: Gold, Azgad
       title: COVID-19 and involuntary hospitalisation: navigating the challenge
        date: 2020-06-18
       words: 1056
      flesch: 38
     summary: Thus, the following question arises: under what conditions does non-compliance with COVID-19-related rules justify psychiatric involuntary hospitalisation, and when might this extraordinary legal option be exploited in the service of public health? Moreover, the absence of data pertaining to the contagion risk of an individual in a specific situation makes it even harder to determine whether the evidence of dangerousness is clear and convincing, as required by minimum legal criteria for psychiatric involuntary commitment.
    keywords: covid-19; hospitalisation; patients
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        item: #1856 of 7819
          id: cord-273209-ou80n3p3
      author: Zheng, Fang
       title: Clinical Characteristics of Children with Coronavirus Disease 2019 in Hubei, China
        date: 2020-03-24
       words: 2619
      flesch: 50
     summary: The majority of pediatric patients had mild symptoms. The occurrence of mild illness in pediatric patients has no clear explanation.
    keywords: cases; children; china; covid-19; infection; patients; years
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        item: #1857 of 7819
          id: cord-273213-b3nla9di
      author: Liu, Jing
       title: Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients
        date: 2020-04-18
       words: 3590
      flesch: 49
     summary: Lymphopenia was observed in 44·4% (12/27) of mild patients and 84·6% (11/13) of severe patients at the onset of the disease. PCA was firstly performed by R package factoextra to identify correlated variables for distinguishing severe patients from mild patients (Figure 4a ).
    keywords: cell; counts; covid-19; disease; figure; levels; lymphocyte; patients
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        item: #1858 of 7819
          id: cord-273235-jxsldz4o
      author: Kennelly, Sean P
       title: Asymptomatic carriage rates and case-fatality of SARS-CoV-2 infection in residents and staff in Irish nursing homes
        date: 2020-09-28
       words: 2150
      flesch: 50
     summary: NH residents are among the frailest in society, with multiple comorbidities and high levels of care needs. The national COVID-19-related casefatality figure for NH residents aged ≥70 years is 21%
    keywords: covid-19; nhs; outbreak; residents; staff
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        item: #1859 of 7819
          id: cord-273262-1vqp188q
      author: Lal, Amos
       title: CT chest findings in coronavirus disease-19 (COVID-19)
        date: 2020-04-04
       words: 683
      flesch: 26
     summary: The readers would also benefit from the information about difference in clinical outcome of these patients with benign initial chest imaging that progressed to prolonged illness and/or further need for invasive mechanical ventilation versus the patients who present with early confluent radiological findings. key: cord-273262-1vqp188q authors: Lal, Amos; Mishra, Ajay Kumar; Sahu, Kamal Kant title: CT chest findings in coronavirus disease-19 (COVID-19) date: 2020-04-04 journal: J Formos Med Assoc DOI: 10.1016/j.jfma.2020.03.010 sha: doc_id: 273262 cord_uid: 1vqp188q nan Letter to the Editor CT chest findings in coronavirus disease-19 To the Editor, We read with great interest the timely presented research article by Cheng et al. outlining the first case of COVID-19 in Taiwan.
    keywords: findings; patients
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        item: #1860 of 7819
          id: cord-273269-bjgfm73q
      author: Meyer, Christian Johannes
       title: The market-reach of pandemics: Evidence from female workers in Ethiopia’s ready-made garment industry
        date: 2020-10-14
       words: 5189
      flesch: 55
     summary: Underlying health conditions that may increase the risk of severe illness from COVID-19 are not common in our sample of HIP workers (Table 2 , Panel (a)). Although we do not have pre-crisis measures of food security for our sample, the reported levels of household 10 To understand risk factors among HIP workers, our survey collects data on six health conditions (cardiovascular diseases, diabetes, hepatitis B, chronic obstructive pulmonary disease, chronic kidney diseases, and cancer) that were commonly observed comorbidities at the onset of the COVID-19 pandemic (Guan et al., 2020) .
    keywords: covid-19; employment; ethiopia; hawassa; health; hip; percent; respondents; sample; survey; workers
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        item: #1861 of 7819
          id: cord-273283-gb0m6fue
      author: Altschul, David J.
       title: A novel severity score to predict inpatient mortality in COVID-19 patients
        date: 2020-10-07
       words: 3373
      flesch: 41
     summary: Then, we determined that low risk patients (0-3 points) had a 11.8% risk of mortality, moderate risk patients (4-7 points) had a 39% risk of mortality and high-risk patients (> 7 points) had a 78% risk of mortality (Fig. 2B) . Furthermore, based on the risk categorization the probability of mortality was 11.8%, 39% and 78% for patient with low (0–3), moderate (4–6) and high (7–10) COVID-19 severity score.
    keywords: cohort; covid-19; hospital; mortality; patients; risk; score; severity; study
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        item: #1862 of 7819
          id: cord-273303-g86w0xt5
      author: Latz, Christopher A.
       title: Early Vascular Surgery Response to the COVID-19 Pandemic: Results of a Nationwide Survey
        date: 2020-05-23
       words: 1886
      flesch: 52
     summary: Further analyses were performed to evaluate whether responses from states with the highest number of COVID-19 cases (New York, New Jersey, Massachusetts, Pennsylvania and California) differed from those with lower case numbers (all other states). responses from states with the highest number of COVID-19 cases (New York, New Jersey, 1 Massachusetts, Pennsylvania and California) differed from those with lower case numbers (all 2 other states).
    keywords: case; covid-19; states; vascular
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        item: #1863 of 7819
          id: cord-273308-rocbfx62
      author: Siguret, Virginie
       title: Are antiphospholipid antibodies associated with thrombotic complications in critically ill COVID-19 patients?
        date: 2020-07-08
       words: 1119
      flesch: 30
     summary: Therefore, we aimed to investigate the prevalence of elevated antiphospholipid antibodies, namely LA, anticardiolipin IgG/IgM and anti-2-glycoprotein-I IgG, and their possible association with thrombotic complications in COVID-19 patients. In COVID-19 patients with thrombosis, persistence period of antiphospholipid antibodies over a 3-month period is required before considering the diagnosis of antiphospholipid syndrome.
    keywords: antibodies; covid-19; patients; ratio
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        item: #1864 of 7819
          id: cord-273315-el2qjtqc
      author: Wang, Ying
       title: Cerebrovascular disease is associated with the risk of mortality in coronavirus disease 2019
        date: 2020-06-30
       words: 1202
      flesch: 44
     summary: To our knowledge, there have been several published articles reporting the association between cerebrovascular disease and the risk of mortality in COVID-19 patients [2] [3] [4] [5] [6] . Seven studies compared cerebrovascular disease in nonsurvival vs. survival patients with a total of 1374 confirmed COVID-19 patients including 392 (28.5%) non-survival cases.
    keywords: covid-19; disease; patients
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        item: #1865 of 7819
          id: cord-273318-82ptu8fi
      author: Prats-Uribe, A.
       title: Heterogeneity and temporal variation in the management of COVID-19: a multinational drug utilization study including 71,921 hospitalized patients from China, South Korea, Spain, and the United States of America
        date: 2020-09-18
       words: 4717
      flesch: 44
     summary: Intensive care drug use data was available from Premier, OPTUM, and VA-OMOP. We created lollipop plots of cumulative incidence of drug use 0 to 30 days after diagnosis and after hospitalization for repurposed and for adjuvant drugs.
    keywords: china; covid-19; data; hydroxychloroquine; license; patients; preprint; review; study; time; use
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        item: #1866 of 7819
          id: cord-273322-zz733a0k
      author: ZHAO, Yang
       title: Coronavirus Disease 2019 versus Influenza A in Children: An Observational Control Study in China
        date: 2020-08-31
       words: 2171
      flesch: 39
     summary: This study compared the clinical characteristics, epidemiology, and routine laboratory test results between 23 inpatients (5.7 ± 3.8 years; 9 boys, 39% of total) with pediatric COVID-19 (recruited from January 1 to March 28, 2020) and age-and sexmatched 69 inpatients and 69 outpatients with pediatric influenza A (from January 1 to December 31, 2019) who received treatment in the Beijing Ditan Hospital in Beijing, China, which has been designated as treatment facility of infectious diseases including COVID-19. The level of alanine aminotransferase in children with COVID-19 is lower than that in inpatients but higher than that in outpatients with influenza A. Pediatric COVID-19 is associated with more frequent family infection, milder symptoms, and milder immune responses relative to pediatric influenza A. Pediatric COVID-19 is usually associated with mild symptoms [2] ; however, knowledge on the differences between pediatric COVID-19 and other pediatric diseases is rare.
    keywords: children; covid-19; influenza; inpatients; outpatients; pediatric; symptoms
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        item: #1867 of 7819
          id: cord-273331-pu4cr3bh
      author: Pinkham, Amy E.
       title: A Longitudinal Investigation of the Effects of the COVID-19 Pandemic on the Mental Health of Individuals with Pre-existing Severe Mental Illnesses
        date: 2020-10-01
       words: 3717
      flesch: 37
     summary: This study compared the severity of pre-pandemic symptoms and affective experiences to current symptoms to evaluate this possibility. By averaging multiple days of assessments, estimates of pre-pandemic experiences and symptoms are likely to be highly precise, thus maximizing the ability to detect change due to the pandemic.
    keywords: covid-19; health; individuals; mental; pandemic; participants; study; symptoms
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        item: #1868 of 7819
          id: cord-273349-penb65x7
      author: Zhang, Chao
       title: Liver injury in COVID-19: management and challenges
        date: 2020-05-31
       words: 1544
      flesch: 36
     summary: Liver diseases including chronic viral hepatitis, non-alcoholic fatty liver disease, and alcohol-related liver disease affect approximately 300 million people in China. However, the exact cause of pre-existing liver conditions has not been outlined in the case studies of COVID-19 and the interaction between existing liver disease and COVID-19 has not been studied.
    keywords: covid-19; liver; patients; sars
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        item: #1869 of 7819
          id: cord-273356-1ius4ksa
      author: Sauceda, John A
       title: Findings From a Probability-Based Survey of United States Households About Prevention Measures Based on Race, Ethnicity, and Age in Response to Severe Acute Respiratory Syndrome Coronavirus 2
        date: 2020-08-29
       words: 2015
      flesch: 47
     summary: We tested for differences between non-Latino white, African American, and Latino respondents on prevention control measures, likelihood of using surveillance/reporting strategies, and household size. Between 20 and 26 April 2020, there were differences between states and cities in SARS-CoV-2 mandates; therefore, some variations in prevention control measures may have depended on region.
    keywords: african; covid-19; latinos; prevention; whites
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        item: #1870 of 7819
          id: cord-273416-332stbjl
      author: Liu, Tianyuan
       title: Transcriptional differences for COVID-19 Disease Map genes between males and females indicate a different basal immunophenotype relevant to the disease
        date: 2020-10-01
       words: 2741
      flesch: 35
     summary: Using DeCovid, we analyzed the extent of gene expression differences among demographic groups across different COVID-19 affected tissues (Table 1) . We used data from the GTEx database, which contains RNA-seq profiles for hundreds of demographically diverse healthy individuals in multiple tissues and allows us to interrogate COVID-19 genes globally or individually.
    keywords: covid-19; differences; disease; expression; genes
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        item: #1871 of 7819
          id: cord-273426-55vu6b3u
      author: Iba, Toshiaki
       title: Coagulopathy of Coronavirus Disease 2019
        date: 2020-05-26
       words: 4539
      flesch: 22
     summary: Platelet counts in COVID-19 patients are variable depending on the reported studies. The potential for increases in platelet counts in COVID-19 patients is suspected to be caused by increased proinflammatory cytokines such as interleukin (IL)-1β and IL-6 produced by the macrophages and monocytes in the lung (26) , and activated platelets may contribute to the lung injury (27) .
    keywords: acute; coagulation; coagulopathy; coronavirus; covid-19; disease; levels; patients; thrombosis
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        item: #1872 of 7819
          id: cord-273433-0014ih0d
      author: Jelinek, Lena
       title: Obsessive-Compulsive Disorder During COVID-19: Turning a Problem into an Opportunity?
        date: 2020-11-05
       words: 5488
      flesch: 42
     summary: The questionnaire inquired about (1) demographic information, such as age and gender, as well as predominant OCD symptoms (obsessions, washing/cleaning, checking, symmetry/ordering, hoarding, and other); (2) reasons for the change in symptom severity (reduced mobility, availability of cleaning/hygiene products, economic factors, lack of availability of doctors/therapist, interpersonal conflicts) as rated on a 5-point Likert scale, with 1 = significantly increased to 5 = significantly decreased; (3) the change in OCD symptom severity (total, obsessions, compulsion, avoidance) as rated on a 5-point Likert scale, with 1 = significantly decreased to 5 = significantly increased (items largely corresponded to a scale used to quantify change during the COVID-10 pandemic in eating disorders, Schlegl, Maier, et al., 2020; Schlegl, Meule, et al., 2020) ; (4) dysfunctional and functional beliefs associated with COVID-19 (for items, see Table 3 ) rated on a Likert scale ranging from 1 = does not apply at all to 5 = totally applies; (5) experience of self-competence associated with prevention of infection with COVID-19 (e.g., giving other people helpful hygiene tips; for items, see Table 4 ) rated on a Likert scale ranging from 1 = totally applies to 6 = does not apply at all. Washers and non-washers differed in the reasons they reported for the change in OCD symptom severity.
    keywords: covid-19; ocd; pandemic; participants; washers
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        item: #1873 of 7819
          id: cord-273477-ifhgbm2e
      author: Lee, Joon Kee
       title: Wearing face masks regardless of symptoms is crucial for preventing the spread of COVID-19 in hospitals
        date: 2020-05-06
       words: 832
      flesch: 42
     summary: 8 To prevent hospital spread of COVID-19, hospital entrance control, wearing of face masks, and strict hand hygiene protocols appear to be effective. Although face masks cannot completely prevent COVID-19, patients spread the virus through coughing, 7 and face masks may reduce the number and travel distance of respiratory droplets.
    keywords: covid-19; hospital; masks
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        item: #1874 of 7819
          id: cord-273492-i483r91m
      author: Fulzele, Sadanand
       title: COVID-19 Virulence in Aged Patients Might Be Impacted by the Host Cellular MicroRNAs Abundance/Profile
        date: 2020-05-09
       words: 3641
      flesch: 45
     summary: In this study, we performed in silico analysis of human cellular miRNAs targeting SARS and COVID-19 (isolates) genome and identified some novel miRNAs. To identify the biological relevance of COVID-19 targeting human cellular miRNAs, KEGG pathway annotation, and GO analysis was performed on target gene pools.
    keywords: analysis; cellular; covid-19; genome; human; isolates; mirnas; sars; table
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        item: #1875 of 7819
          id: cord-273493-xsroivzj
      author: Manalo, Iviensan F.
       title: A Dermatologic Manifestation of COVID-19: Transient Livedo Reticularis
        date: 2020-04-10
       words: 472
      flesch: 45
     summary: Ten days after testing positive, and with complete clinical convalescence of COVID-19 symptoms, she was sitting outside in long pants under direct sunlight for approximately 20-30 minutes. Cutaneous manifestations in COVID-19: a first perspective Livedo reticularis: an update Acute pulmonary embolism and COVID-19 pneumonia: a random association?
    keywords: covid-19; livedo
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        item: #1876 of 7819
          id: cord-273495-hruq0hdw
      author: Waffo Tchounga, C.A.
       title: Composition analysis of falsified chloroquine phosphate samples seized during the COVID-19 pandemic
        date: 2020-11-12
       words: 3177
      flesch: 49
     summary: key: cord-273495-hruq0hdw authors: Waffo Tchounga, C.A.; Sacre, P.Y.; Ciza, P.; Ngono, R.; Ziemons, E.; Hubert, Ph.; Marini, R.D. title: Composition analysis of falsified chloroquine phosphate samples seized during the COVID-19 pandemic date: 2020-11-12 journal: J Pharm Biomed Anal DOI: 10.1016/j.jpba.2020.113761 sha: doc_id: 273495 cord_uid: hruq0hdw The proliferation of falsified medicines can cause serious public health issues, particularly in the context of a global pandemic such as the actual COVID-19 pandemic. These suspect chloroquine samples were seized by local authorities as being part of the WHO alert list.
    keywords: chloroquine; covid-19; imaging; medicines; paracetamol; phosphate; presence; raman; samples
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        item: #1877 of 7819
          id: cord-273505-pcsw3vmx
      author: Liu, Xiaosheng
       title: High-Dose Intravenous Immunoglobulins in the Treatment of Severe Acute Viral Pneumonia: The Known Mechanisms and Clinical Effects
        date: 2020-07-14
       words: 10785
      flesch: 21
     summary: In severe SARS patients, the activation of Th1-related cytokines and chemokines (e.g., IL-1, IL-6, IL-12) was involved in hyperinflammatory conditions (141) . In a randomized controlled trial, IVIg therapy efficiently improved the serum IgG concentration of severe SARS patients compared to the control group (222) .
    keywords: cells; covid-19; cytokine; dose; effects; high; igg; immune; immunoglobulin; infection; inflammatory; influenza; intravenous; ivig; patients; sars; syndrome; therapy; treatment; virus
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        item: #1878 of 7819
          id: cord-273522-ygd19p05
      author: Rothrock, Robert J.
       title: By the Numbers Analysis of COVID-19’s Effect on a Neurosurgical Residency at the Epicenter
        date: 2020-07-17
       words: 752
      flesch: 46
     summary: Neurosurgical cases during the crisis were analyzed and compared to seven-week periods from 2019 and 2020. Neurosurgical cases during the crisis were analyzed and compared to seven-week 14 periods from 2019 and 2020.
    keywords: covid-19; outbreak
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        item: #1879 of 7819
          id: cord-273541-47n8i2qg
      author: Mena Lora, Alfredo J.
       title: Feasibility and impact of inverted classroom methodology for coronavirus disease 2019 (COVID-19) pandemic preparedness at an urban community hospital
        date: 2020-10-20
       words: 1544
      flesch: 50
     summary: We describe our experience using inverted classroom methodology (ICM) for COVID-19 pandemic preparedness in a small hospital with limited infection prevention staff. The evidence for 'flipping out': a systematic review of the flipped classroom in nursing education Flipped OR: a modified didactical concept for a surgical clerkship in Oral and Maxillofacial Surgery Fear of severe acute respiratory syndrome (SARS) among health care workers Long-term psychological and occupational effects of providing hospital healthcare during SARS outbreak Impact of inverted classroom methodology (ICM) on healthcare worker (HCW) attitudes and perceptions about COVID-19 Acknowledgments.
    keywords: covid-19; icm; infection; pandemic; use
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        item: #1880 of 7819
          id: cord-273553-xp4nfnq3
      author: Ramatillah, D. L.
       title: TREATMENT PROFILES AND CLINICAL OUTCOMES OF COVID-19 PATIENTS AT PRIVATE HOSPITAL IN JAKARTA
        date: 2020-10-16
       words: 3973
      flesch: 49
     summary: Objectives: To find out the effective treatment as an antiviral agent for COVID-19, to determine the correlation between sociodemography with clinical outcomes and duration of treatment, and to determine the relationship between comorbidities with clinical outcomes and duration of treatment for COVID-19 patients. The survival analysis for COVID-19 patients using the Kaplan Meier method showed that patients receiving Oseltamivir + Hydroxychloroquine had an average survival rate of about 83% after undergoing treatment for about ten days.
    keywords: covid-19; oseltamivir; patients; people; study; treatment
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        item: #1881 of 7819
          id: cord-273554-dm3mwbyp
      author: Dhuyvetter, Amanda
       title: Coronavirus Disease 2019 in Pregnancy: The Experience at an Urban Safety Net Hospital
        date: 2020-10-31
       words: 1297
      flesch: 44
     summary: There have been conflicting data about the severity of COVID-19 disease course in pregnant women, with most US data suggesting an increase in severity and increased need for hospitalization and intubation in obstetric patients. Of pregnant women receiving their care with Cook County Health and Hospital Systems, 11.1% tested positive for COVID-19, as did 5.1% of asymptomatic women.
    keywords: covid-19; disease; women
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        item: #1882 of 7819
          id: cord-273556-rvo0vyk3
      author: Zhang, Kui
       title: The combined therapy of a traditional Chinese medicine formula and Western medicine for a critically ill case infected with COVID-19
        date: 2020-06-09
       words: 2101
      flesch: 47
     summary: key: cord-273556-rvo0vyk3 authors: Zhang, Kui; Tian, Maolu; Zeng, Yang; Wang, Linwen; Luo, Sha; Xia, Wei; Zhang, Xiangyan; Zha, Yan title: The combined therapy of a traditional Chinese medicine formula and Western medicine for a critically ill case infected with COVID-19 date: 2020-06-09 journal: Complement Ther Med DOI: 10.1016/j.ctim.2020.102473 sha: doc_id: 273556 cord_uid: rvo0vyk3 OBJECTIVE: Presentation of a case illustrating the benefits of traditional Chinese medicine (TCM) for treatment of Coronavirus disease 2019 (COVID-19) in critically ill patients. Our case report suggests that collaborative treatments with traditional Chinese medicine prove beneficial in the management of COVID-19 in critically ill patients.
    keywords: covid-19; day; hospital; medicine; patient; tcm
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        item: #1883 of 7819
          id: cord-273567-8fp3a9h8
      author: Zipprich, Hannah M.
       title: Knowledge, Attitudes, Practices, and Burden During the COVID-19 Pandemic in People with Parkinson’s Disease in Germany
        date: 2020-05-29
       words: 5377
      flesch: 51
     summary: Patients with limited knowledge were older (mean age, 74.4 years; SD = 7.2) than patients with good knowledge (mean age, 70.0 years; SD = 8.5) (p = 0.03). Patients who felt that they were very well informed about COVID-19 were more likely to search actively for further information (p = 0.03) than patients who felt that they were not sufficiently informed about COVID-19; in contrast, none of the five patients who felt that they were poorly informed about COVID-19 actively searched for information.
    keywords: covid-19; disease; information; knowledge; measures; parkinson; patients; study
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        item: #1884 of 7819
          id: cord-273587-nja58vxw
      author: Rendeiro, A. F.
       title: Longitudinal immune profiling of mild and severe COVID-19 reveals innate and adaptive immune dysfunction and provides an early prediction tool for clinical progression
        date: 2020-09-09
       words: 8918
      flesch: 40
     summary: Indeed, similar to previous reports 17, 18, 50 , T cells displayed an overall exhausted phenotype, with overexpression of VISTA, TIM3, LAG3, TIGIT, and PD-1 coinhibitory receptors in COVID-19 patient T cell populations. Quantification of immune cell populations is available as a Supplementary Table file.
    keywords: cells; covid-19; disease; donors; expression; figure; immune; license; medrxiv; patients; perpetuity; populations; preprint; september; severity; version
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        item: #1885 of 7819
          id: cord-273598-6hk2oxj9
      author: Metcalfe, Peter E.
       title: Low dose radiation therapy for COVID-19 pneumonia: brief review of the evidence
        date: 2020-08-10
       words: 1987
      flesch: 49
     summary: Effect of dexamethasone in hospitalised patients with COVID-19: prelininary report Low-dose whole-lung radiation for COVID-19 pneumonia: planned day-7 interim analysis of an ongoing clinical trial Is low dose radiation therapy a potential treatment for COVID-19 pneumonia? Treatment of COVID-19 pneumonia patients with X-rays Low dose radiation as a treatment for COVID-19 pneumonia: a threat or real opportunity It is confounding that the first clinical trial using 1.5 Gy is high compared with other historical pneumonia treatment doses [2] .
    keywords: covid-19; dose; patients; pneumonia; treatment
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        item: #1886 of 7819
          id: cord-273601-icituitn
      author: Liu, M.
       title: Forecasting the Spread of COVID-19 under Different Reopening Strategies
        date: 2020-05-29
       words: 6275
      flesch: 60
     summary: We drop 3 of the remaining counties because we do not have social distancing data for 2 of them, and we cannot match the demographic data for a third (Oglala Lakota County, SD). We use social distancing data from the company SafeGraph, which collects cellphone GPS data from U.S. residents, and has made them available for free to academics studying COVID-19.
    keywords: cases; county; covid-19; data; distancing; level; model; number; preprint
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        item: #1887 of 7819
          id: cord-273602-cq276tj8
      author: Bavishi, Chirag
       title: Acute myocardial injury in patients hospitalized with COVID-19 infection: A review
        date: 2020-06-06
       words: 2121
      flesch: 23
     summary: Circulation ST-Segment Elevation in Patients with Covid-19 -A Case Series Clinical observation and management of COVID-19 patients Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis ACTT-1 Study Group Members. Remdesivir for the Treatment of Covid-19 -Preliminary Report Acute Cardiovascular Conditions During the COVID-19 Pandemic: A Multicenter Tertiary Care Experience Coronavirus Disease 2019 (COVID-19) Infection and Renin Angiotensin System Blockers Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Renin-Angiotensin-Aldosterone System Blockers and the Risk of Covid-19 Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19 Association of Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Testing Positive for Coronavirus Disease 2019 (COVID-19) COVID-19 and Renin Angiotensin Blockers: Current Evidence and Recommendations Wang Y et al 12
    keywords: cardiac; clinical; coronavirus; covid-19; injury; myocardial; patients
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        item: #1888 of 7819
          id: cord-273604-0w5shxmf
      author: Psevdos, George
       title: Halting a SARS-CoV-2 Outbreak in a U.S. Veterans Affairs Nursing Home
        date: 2020-11-03
       words: 1242
      flesch: 43
     summary: Interim SARS-CoV-2 testing guidelines for nursing home residents and healthcare personnel Although nationally the virus spreads like wildfire in nursing homes (among residents and working staff), the Department of Veterans Affairs (VA) reported lower COVID-19 rates in their affiliated nursing homes in a U.S. Congressional hearing.
    keywords: care; covid-19; nursing; outbreak; veterans
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        item: #1889 of 7819
          id: cord-273614-qmp2tqtb
      author: Tahir, Faryal
       title: Cardiac Manifestations of Coronavirus Disease 2019 (COVID-19): A Comprehensive Review
        date: 2020-05-08
       words: 7182
      flesch: 49
     summary: This high viability time period on different surfaces can lead to indirect transmission of SARS-CoV-2 to healthy individuals if they come into contact with objects used on COVID-19 patients, such as stethoscope or thermometer [18] . To intercept fatality among COVID-19 patients, the authors suggested close monitoring of the cardiac functioning of all patients, especially the severe and critical ones, and to seek possible interventions for patients evincing features of abnormal cardiac injury
    keywords: cardiac; cases; coronavirus; cov-2; covid-19; disease; injury; levels; median; mortality; patients; sars
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        item: #1890 of 7819
          id: cord-273618-klj6asdz
      author: Jain, Ankur
       title: Potential ‘significance’ of monoclonal gammopathy of ‘undetermined significance’ during COVID-19 pandemic
        date: 2020-07-24
       words: 1731
      flesch: 38
     summary: 2. Underlying 'MGUS', and clone-directed therapies could compromise vaccine efficacy Apart from the routine seasonal influenza, and pneumococcal vaccines, vaccination against SARS-CoV-2 when available, must be considered for patients with MGCS *** Bortezomib reduced the post-vaccine protective antibody titer by  30% in patients with SLE 26Consider usual SARS-CoV-2 vaccination in MGCS patients on a PI *** DARA did not affect the antibody response to seasonal influenza vaccine in patients with heavily pre-treated MM 27Consider usual SARS-CoV-2 vaccination for patients with MGCS on DARA.Rituximab causes profound B-cell depletion, and complete B-cell recovery could take 6-12 months after the last dose ****28Consider SARS-CoV-2 vaccination either prior to, or atleast 6-months after the last dose of Rituximab in MGCS patients IMiDs were shown to augment the vaccine response 29 Consider usual SARS- General measures of hand hygiene and sanitisation are mandatory for all MGCS patients. Screening the admitted COVID-19 patients for the presence of MGUS may provide some clue to the excess thrombotic risk, and/or different pattern of coagulopathy conferred by MGUS to COVID-19 patients MGUS: monoclonal gammopathy of undetermined significance; COVID-19: coronavirus disease 2019; SARS-CoV-2: severe acute respiratory distress syndrome coronavirus 2 * Antibody-based assays have a relatively high false-negative rate as compared to conventional polymerase chain reaction (PCR)-based assays, and are therefore, not routinely recommended for COVID-19 diagnosis during the acute stage.
    keywords: covid-19; mgcs; mgus; patients; response
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        item: #1891 of 7819
          id: cord-273638-mmlwh87u
      author: Tso, Ivy F.
       title: Alarming levels of psychiatric symptoms and the role of loneliness during the COVID-19 epidemic: A case study of Hong Kong
        date: 2020-08-23
       words: 4393
      flesch: 44
     summary: key: cord-273638-mmlwh87u authors: Tso, Ivy F.; Park, Sohee title: Alarming levels of psychiatric symptoms and the role of loneliness during the COVID-19 epidemic: A case study of Hong Kong date: 2020-08-23 journal: Psychiatry Res DOI: 10.1016/j.psychres.2020.113423 sha: doc_id: 273638 cord_uid: mmlwh87u Public health strategies to curb the spread of the coronavirus involve sheltering at home and social distancing are effective in reducing the transmission rate, but the unintended consequences of prolonged social isolation on mental health have not been investigated. Thus, Hong Kong is a model case for the population-wide practice of effective social distancing and provides an opportunity to examine the impact of loneliness on mental health during the COVID-19.
    keywords: covid-19; health; hong; kong; loneliness; respondents; social
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        item: #1892 of 7819
          id: cord-273641-8l57mnjt
      author: Sadr, Sara
       title: Isolated severe thrombocytopenia in a patient with COVID-19: A case report
        date: 2020-05-29
       words: 1439
      flesch: 40
     summary: More importantly, isolated severe thrombocytopenia with no respiratory illness is rarely seen in COVID-19 patients. A 57-year-old woman, a pharmacist with considerable exposure to COVID-19 patients, presented to a clinic in Tehran with headache and malaise with the onset of 5 days prior to admission.
    keywords: covid-19; platelet; symptoms; thrombocytopenia
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        item: #1893 of 7819
          id: cord-273644-m6cub4sx
      author: Zhang, Yimin
       title: A Promising Anti-Cytokine-Storm Targeted Therapy for COVID-19: The Artificial-Liver Blood-Purification System
        date: 2020-03-20
       words: 1659
      flesch: 35
     summary: An artificial-liver blood-purification system was used to treat patients with severe H7N9 influenza infection who had confirmed cytokine storm and rapidly deteriorating condition Hypercytokinemia, also known as 'cytokine storm, is a frequently occurring feature of severe infections with SARS, MERS, H5N1 influenza, and H7N9 influenza; it is associated with disease severity and is a predictor of mortality
    keywords: blood; infection; liver; patients; purification
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        item: #1894 of 7819
          id: cord-273646-ne7qfjd6
      author: Shan Chan, Christine Hui
       title: Safeguarding Non-COVID-19 Research: Looking Up from Ground Zero
        date: 2020-05-30
       words: 1051
      flesch: 36
     summary: Worldwide, as resources are directed toward accelerating the research into unravelling the mechanism of COVID-19 pathophysiology, concerns have been raised regarding the future of clinical research in United Kingdom and elsewhere during the current pandemic. Worldwide, as resources are directed toward accelerating the research into unravelling the mechanism of COVID-19 pathophysiology, concerns have been raised regarding the future of clinical research in United Kingdom (2) , United States (3) and countries that have invested heavily in biomedical sciences.
    keywords: covid-19; pandemic; research
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        item: #1895 of 7819
          id: cord-273656-xo82zyi6
      author: Burry, Lisa D.
       title: It Takes a Village… Contending with Drug Shortages During Disasters
        date: 2020-08-14
       words: 4567
      flesch: 31
     summary: Therapeutic alternatives and strategies for drug conservation in the intensive care unit during times of drug shortages: a report of the Ontario COVID-19 ICU Drug Task Force A Toolkit for Improved Understanding and Transparency of Drug Shortage Response in Canada The drug shortage crisis in the United States: causes, impact, and management strategies Drug shortages in developed countries -reasons, therapeutic consequences, and handling Medication shortages during the COVID-19 crisis: what we must do Economic and technological drivers of generic sterile injectable drug shortages US Propofol Drug Shortages: A Review of the Problem and Stakeholder Analysis Why are there so many drug shortages? Drug Shortages in the United States: Are Some Prices Too Low? While cisatracurium is the agent of choice for many institutions, in the setting of drug shortages, consider reserving cisatracurium (and atracurium) for patients with endorgan dysfunction and use vecuronium or rocuronium when both kidney and liver function are preserved Addressing the global shortage of, and access to, medicines and vaccines Report by the Director-General BACKGROUND Medicines shortages: Global approaches to addressing shortages of essential medicines in health systems Medicine shortages: Gaps between countries and global perspectives Essential ICU drug shortages for COVID-19: what can frontline clinicians do? Potential of chloroquine and hydroxychloroquine to treat COVID-19 causes fears of shortages among people with systemic lupus erythematosus
    keywords: care; countries; covid-19; drug; manufacturers; patients; pharmaceutical; production; shortages; strategies; supply; use
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        item: #1896 of 7819
          id: cord-273689-gvzvvrfx
      author: Huang, Jiaofeng
       title: Hypoalbuminemia predicts the outcome of COVID‐19 independent of age and co‐morbidity
        date: 2020-05-25
       words: 1696
      flesch: 38
     summary: WHO characterizes COVID-19 as a pandemic Strengthening China's public health response system: From SARS to COVID-19 Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures Controversial treatments: an updated understanding of the coronavirus disease 2019 Clinical characteristics of coronavirus disease 2019 in China Comorbidity and its impact on 1590 patients with Covid-19 in China: a nationwide analysis Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study COVID-19 in post-transplantation patients-report of two cases Individualized prediction nomograms for disease progression in mild COVID-19 The impact of COPD and smoking history on the severity of COVID-19: a systemic review and metaanalysis Lymphopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a systemic review and meta-analysis Liver impairment in COVID-19 patients: a retrospective analysis of 115 cases from a single center in Wuhan city Dysregulation of immune response in patients with COVID-19 in Wuhan, China. The potential therapeutic value of albumin infusion in COVID‐19 should be further explored at the earliest. decreased albumin level is common in severe COVID-19, 7,12 but the change in albumin does not parallel the severity of hepatocellular injury in This suggests that there may be mechanisms other than a hepatocellular injury that explains the profound hypoalbuminemia seen in COVID-19.
    keywords: albumin; covid-19; hypoalbuminemia; patients; study
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        item: #1897 of 7819
          id: cord-273725-0i0xg7gv
      author: Gao, Y.
       title: Cancer is associated with the severity and mortality of patients with COVID-19: a systematic review and meta-analysis
        date: 2020-05-06
       words: 4249
      flesch: 47
     summary: Pairwise meta-analyses were conducted to compute the odds ratio (OR) and 95% CI of cancer prevalence in COVID-19 patients with or without severe illness, and non-survivors or survivors. key: cord-273725-0i0xg7gv authors: Gao, Y.; Liu, M.; Shi, S.; Chen, Y.; Sun, Y.; Chen, J.; Tian, J. title: Cancer is associated with the severity and mortality of patients with COVID-19: a systematic review and meta-analysis date: 2020-05-06 journal: nan DOI: 10.1101/2020.05.01.20087031 sha: doc_id: 273725 cord_uid: 0i0xg7gv Background: Cancer patients are considered a highly vulnerable population in the COVID-19 epidemic, but the relationship between cancer and the severity and mortality of patients with COVID-19 remains unclear.
    keywords: cancer; covid-19; license; medrxiv; patients; preprint
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        item: #1898 of 7819
          id: cord-273741-ipnt6g0i
      author: Khan, Adeel A
       title: Fluid Replacement Versus Fluid Restriction in COVID-19 Associated Hyponatremia
        date: 2020-07-08
       words: 1189
      flesch: 41
     summary: Hypovolemic hyponatremia should be distinguished from SIADH as these conditions employ different management strategies, and early diagnosis and management of hypovolemic hyponatremia affects morbidity and mortality. The patient had hypovolemic hyponatremia due to gastrointestinal (GI) losses and was managed with saline infusion for correction of hyponatremia with improvement in his clinical status.
    keywords: covid-19; hyponatremia; siadh
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        item: #1899 of 7819
          id: cord-273758-hhd8xnve
      author: Ciardullo, S.
       title: Impact of diabetes on COVID-19-related in-hospital mortality: a retrospective study from Northern Italy
        date: 2020-08-10
       words: 3408
      flesch: 41
     summary: Spread of SARS-CoV-2 in the Icelandic population Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention COVID-19 infection in Italian people with diabetes: lessons learned for our future (an experience to be used) Pathophysiology and management strategies for hyperglycemia for patients with acute illness during and following a hospital stay Patients with diabetes are at higher risk for severe illness from COVID-19 Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia-a systematic review, meta-analysis, and metaregression Diabetes is a risk factor for the progression and prognosis of COVID-19 Clinical characteristics and risk factors for mortality of COVID-19 patients with diabetes in Wuhan Severe obesity, increasing age and male sex are independently associated with worse in-hospital outcomes, and higher in-hospital mortality Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study Outcomes in patients with hyperglycemia affected by Covid-19: can we do more on glycemic control? A case-control study Effects of SGLT2 inhibitors on systemic and tissue low-grade inflammation: the potential contribution to diabetes complications and cardiovascular disease Lack of efficacy of SGLT2-i in severe pneumonia related to novel coronavirus (nCoV) infection: no little help from our friends Renin-angiotensin-aldosterone system blockers and the risk of Covid-19 Age and multimorbidity predict death among COVID-19 patients Clinical characteristics and prognostic factors in COVID-19 patients aged≥ 80 years Acknowledgements Open access funding provided by Università degli Studi di Milano -Bicocca within the CRUI-CARE Agreement..
    keywords: covid-19; diabetes; disease; hospital; mortality; patients; risk; study
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        item: #1900 of 7819
          id: cord-273772-nolyx9g3
      author: Calder-Gerver, G. D.
       title: Real-Time Monitoring of COVID-19 in Scotland
        date: 2020-08-02
       words: 2406
      flesch: 54
     summary: The NRS death records facilitate a comparison of COVID-19 deaths in different locations, such as care homes and hospitals ( Figure 3 ). These numbers are expected to capture the majority of COVID-19 deaths occurring in hospitals, but a lower proportion of deaths outwith hospital settings, especially in late March and early April (when testing was mostly restricted to hospitalised patients [10, 11] ).
    keywords: covid-19; deaths; preprint; ratios
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        item: #1901 of 7819
          id: cord-273774-mg0wq9g0
      author: Votto, Martina
       title: How pediatric resident’s life has changed during the COVID-19 pandemic
        date: 2020-10-16
       words: 1059
      flesch: 37
     summary: Pediatric residents continue to be essential pillars in managing and treating pediatric diseases and are currently fundamental health care providers for every ill patient, including children and adolescents with COVID-19. Ital J Pediatr DOI: 10.1186/s13052-020-00920-6 sha: doc_id: 273774 cord_uid: mg0wq9g0 Since the World Health Organization declared Coronavirus Disease 2019 (COVID-19) a global pandemic, a few articles were published on the working experience of pediatric residents, especially from the most exposed countries worldwide.
    keywords: covid-19; pandemic; residents
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        item: #1902 of 7819
          id: cord-273775-ncfzz3kh
      author: Drissi, Farouk
       title: Re: “Strategy for the practice of digestive and oncologic surgery in COVID-19 epidemic situation”. As regards the detection of coronavirus in peritoneal fluid
        date: 2020-10-16
       words: 279
      flesch: 32
     summary: That said, the presence of the coronavirus in peritoneal fluid, which would induce a risk of contamination in digestive surgery, is currently under debate. Strategy for the practice of digestive and oncologic surgery in COVID-19 epidemic situation COVID-19 not detected in peritoneal fluid: a case of laparoscopic appendicectomy for acute appendicitis in a COVID-19-infected patient SARS-CoV-2 is present in peritoneal fluid in COVID-19 patients.
    keywords: surgery
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        item: #1903 of 7819
          id: cord-273778-68wxa782
      author: Lawal, Olanrewaju
       title: Movement and risk perception: evidence from spatial analysis of mobile phone-based mobility during the COVID-19 lockdown, Nigeria
        date: 2020-11-02
       words: 6776
      flesch: 50
     summary: Place category aggregated mobility trend For the retail and recreation category (Fig. 2a) , Sokoto showed median mobility of zero while some States experienced an increase (compared to baseline) mobility for this place category. GeoJournal DOI: 10.1007/s10708-020-10331-z sha: doc_id: 273778 cord_uid: 68wxa782 The emergence of COVID-19 across the globe prompted many countries to institute total lockdown or other models of mobility restrictions to mitigate the spread of the disease.
    keywords: cases; covid-19; decline; lockdown; mobility; nigeria; people; perception; place; risk; spread; states; trend
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        item: #1904 of 7819
          id: cord-273785-mxehiuq1
      author: Soofi, Moslem
       title: Using Insights from Behavioral Economics to Mitigate the Spread of COVID-19
        date: 2020-05-21
       words: 3400
      flesch: 38
     summary: Present bias is an explanation for why people do not behave in their own best interests and why they have difficulty adhering to preventive health behaviors such as social distancing, even when they wish to adhere [15] . Present bias has been shown to be a significant predictor of a wide variety of health behaviors [14] .
    keywords: behaviors; bias; covid-19; economics; health; people; risk
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        item: #1905 of 7819
          id: cord-273794-gvjwvabm
      author: Palomar-Ciria, Nora
       title: SCHIZOPHRENIA AND COVID-19 DELIRIUM.
        date: 2020-05-27
       words: 1012
      flesch: 48
     summary: In this work, we present the case of a man diagnosed with schizophrenia, who had been stable for more than 20 years and that presented with an atypical picture of psychotic and confusional symptoms related to COVID-19 infection. In this work, we present the case of a man diagnosed with schizophrenia, who had been stable for more than 20 years and that presented with an atypical picture of psychotic and confusional symptoms related to COVID-19 infection.
    keywords: covid-19; infection; patients
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        item: #1906 of 7819
          id: cord-273811-ymnvwwjw
      author: Rubio-Rivas, M.
       title: Beneficial and Harmful Outcomes of Tocilizumab in Severe COVID-19: A Systematic Review and Meta-Analysis
        date: 2020-09-08
       words: 4830
      flesch: 45
     summary: The majority of included studies were carried out in different hospitals in high-income countries in America and Europe, such as the US ( (11, 12) . Although no standard doses have specifically been established for TCZ to be used in COVID-19, a vast majority of included studies used a single dose of 400-800 mg iv or 162-324 mg sc, and a few of them, allowed a second or even a third dose in case of worsening.
    keywords: covid-19; medrxiv; mortality; patients; preprint; review; studies; tcz; version
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        item: #1907 of 7819
          id: cord-273815-7ftztaqn
      author: Gupta, R. K.
       title: Systematic evaluation and external validation of 22 prognostic models among hospitalised adults with COVID-19: An observational cohort study
        date: 2020-07-26
       words: 4920
      flesch: 35
     summary: Importantly, prognostic models may have additional value in patient stratification for emerging drug therapies 6, 7 . These include models aiming to predict a diagnosis of COVID-19, and prognostic models, aiming to predict disease outcomes.
    keywords: covid-19; holder; july; license; medrxiv; models; perpetuity; preprint; version
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        item: #1908 of 7819
          id: cord-273816-4sxe7s03
      author: Xing, Q.-Q.
       title: Liver Chemistries in COVID-19 Patients with Survival or Death: A Meta-Analysis
        date: 2020-05-01
       words: 2421
      flesch: 53
     summary: Thus, we performed a meta-analysis of published liver manifestations and described the liver damage in COVID-19 patients with death or survival. retrospective study Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus 399 Disease Influence factors of death 401 risk among COVID-19 patients in Wuhan, China: a hospital-based case-cohort study Acute liver injury and its 404 association with death risk of patients with COVID-19: a hospital-based prospective 405 case-cohort study No reuse allowed without permission.
    keywords: author; funder; medrxiv; preprint
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        item: #1909 of 7819
          id: cord-273828-557vlq9d
      author: Brito, Carlos Antunes
       title: Mechanisms and consequences of COVID-19 associated liver injury: What can we affirm?
        date: 2020-08-27
       words: 3096
      flesch: 47
     summary: key: cord-273828-557vlq9d authors: Brito, Carlos Antunes; Barros, Fabio Marinho; Lopes, Edmundo Pessoa title: Mechanisms and consequences of COVID-19 associated liver injury: What can we affirm? date: 2020-08-27 journal: Since the first reports of coronavirus disease 2019 (COVID-19) cases in December 2019 in China, numerous papers have been published describing a high frequency of liver injury associated with severe acute respiratory syndrome coronavirus 2 infection, many of them proposing a link between these findings and patient outcomes.
    keywords: covid-19; disease; injury; levels; liver; patients
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        item: #1910 of 7819
          id: cord-273829-t5cuop5c
      author: Görgülü, Özkan
       title: rRT-PCR Results of a Covid-19 Diagnosed Geriatric Patient
        date: 2020-10-17
       words: 1490
      flesch: 46
     summary: The nucleic acid test functions as the gold standard method for confirming the SARS-COV-2 infection; however, some recent studies have detected false negative results of real-time reverse transcriptase polymerase chain reaction (rRT-PCR) Both lung and cardiovascular injuries are common in the management of COVID-19 infections, especially those with only cardiovascular disease symptoms [7] .
    keywords: covid-19; patient; pcr; rrt; test
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        item: #1911 of 7819
          id: cord-273833-yf8kt84e
      author: Mejia, Rojelio
       title: Global COVID-19 Efforts as the Platform to Achieving the Sustainable Development Goals
        date: 2020-08-20
       words: 2546
      flesch: 45
     summary: To be successful and achieve the global goals including the control of pandemics such as the one seen from the COVID-19, we must rely on strong leadership leading to impactful public policies and global collaborations, including global COVID-19 vaccinations, and potentially linking them to programs for childhood and adult vaccinations and programs for malaria, tuberculosis, HIV/AIDS, and neglected tropical disease treatments. Major US cities had high levels of COVID-19 infections and a higher prevalence in those living below the poverty line [28] .
    keywords: areas; coronavirus; covid-19; disease; health; populations; poverty
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        item: #1912 of 7819
          id: cord-273869-buavj9mm
      author: Rosés-Gibert, Pau
       title: Acral lesions in a pediatric population during the COVID-19 pandemic: a case series of 36 patients from a single hospital in Spain
        date: 2020-09-08
       words: 1896
      flesch: 46
     summary: A novel coronavirus from patients with pneumonia in China WHO declares COVID-19 a pandemic Cutaneous manifestations in COVID-19: a first perspective Urticarial eruption in COVID-19 infection Viral exanthem in COVID-19, a clinical enigma with biological significance Varicella-like exanthem as a specific COVID-19-associated skin manifestation: multicenter case series of 22 patients COVID-19) infection-induced chilblains: a case report with histopathological findings A case of COVID-19 presenting in clinical picture resembling chilblains disease: first report from the Middle East Chilblain and acral purpuric lesions in Spain during covid confinement: retrospective analysis of 12 cases Chilblain-like lesions during COVID-19 epidemic: a preliminary study on 63 patients Chilblain-like lesions on feet and hands during the COVID-19 pandemic Acral cutaneous lesions in the time of COVID-19 Acute acro-ischemia in the child at the time of COVID-19 Are chilblainlike acral skin lesions really indicative of COVID-19? key: cord-273869-buavj9mm authors: Rosés-Gibert, Pau; Gimeno Castillo, Javier; Saenz Aguirre, Amaia; De la Torre Gomar, Francisco Javier; Carnero González, Lucía; Martinez de Lagrán Alvarez de Arcaya, Zuriñe; Gonzalez-Perez, Ricardo title: Acral lesions in a pediatric population during the COVID-19 pandemic: a case series of 36 patients from a single hospital in Spain date: 2020-09-08 journal:
    keywords: covid-19; infection; lesions; manifestations; patients
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        item: #1913 of 7819
          id: cord-273897-hkt322bt
      author: Seijts, Gerard
       title: The Myriad Ways in Which COVID-19 Revealed Character
        date: 2020-05-14
       words: 4824
      flesch: 42
     summary: In addition to many national leaders doing their best to remain calm and goal focused, that is, to show temperance, business leaders also stepped up to the plate. However, a unique aspect of leader character is that it is linked to an individual's J o u r n a l P r e -p r o o f 5 disposition rather than one's position within an organization.
    keywords: article; character; citizens; coronavirus; covid-19; crisis; individuals; leaders; leadership; organizations; pandemic; public
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        item: #1914 of 7819
          id: cord-273907-58jufmx7
      author: Shen, Kun-Ling
       title: Global Pediatric Pulmonology Alliance recommendation to strengthen prevention of pediatric seasonal influenza under COVID-19 pandemic
        date: 2020-09-13
       words: 1726
      flesch: 38
     summary: Countries and regions with ample resources should implement free influenza vaccination in child care centers, kindergartens and schools, so as to increase the coverage rate of influenza vaccination among the pediatric population [16] . These organizations vigorously advocate influenza vaccination as the primary measure for pandemic prevention and control, so as to minimize the interference of an influenza epidemic during the prevention and control of the COVID-19 pandemic situation.
    keywords: children; covid-19; health; influenza; vaccination; vaccine
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        item: #1915 of 7819
          id: cord-273913-xem3alih
      author: Marraha, Farah
       title: A Review of the Dermatological Manifestations of Coronavirus Disease 2019 (COVID-19)
        date: 2020-08-11
       words: 4237
      flesch: 47
     summary: Clinical and pathological features in 20 COVID-19 patients Cutaneous signs in COVID-19 patients: a review Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Multisystem inflammatory syndrome in children and adolescents temporally related to COVID-19 Hyperinflammatory shock in children during COVID-19 pandemic Selfreported hand eczema in a hospital population e adverse skin reactions of health care workers using personal protective equipment for COVID-19 Breakthrough: chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial A pilot study of hydroxychloroquine in treatment of patients with moderate COVID-19 Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial Should chloroquine and hydroxychloroquine be used to treat COVID-19? Healthcare institutions and policymakers developed various plans to control the pandemic, including preparing hospitals and clinics, developing a strategy for the identification of suspected COVID-19 cases, and implementing a strategy to reduce the spread [24] .
    keywords: cases; coronavirus; covid-19; disease; infection; lesions; manifestations; patients; sars; skin; syndrome
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        item: #1916 of 7819
          id: cord-273918-knlc3bxh
      author: Holmes, Emily A
       title: Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science
        date: 2020-04-15
       words: 10283
      flesch: 29
     summary: Terms 'physical distancing' and 'emotional closeness' should be used and not 'social distancing' when defeating the Covid-19 pandemic The global syndemic of obesity, undernutrition, and climate change: The Lancet Commission report The impact of communications about swine flu (influenza A H1N1v) on public responses to the outbreak: results from 36 national telephone surveys in the UK Avoidance behaviors and negative psychological responses in the general population in the initial stage of the H1N1 pandemic in Hong Kong Social isolation in mental health: a conceptual and methodological review Loneliness as a specific risk factor for depressive symptoms: crosssectional and longitudinal analyses Patients with mental health disorders in the COVID-19 epidemic Annual research review: secular trends in child and adolescent mental health Cross-cohort change in adolescent outcomes for children with mental health problems Mental health interventions in schools in high-income countries Preventing childhood anxiety disorders: is an applied game as effective as a cognitive behavioral therapy-based program? COVID-19 and the consequences of isolating the elderly Survivors' priority themes and questions for research The coronavirus disease 2019 (COVID-19) pandemic is having a profound effect on all aspects of society, including mental health and physical health.
    keywords: anxiety; coronavirus; cov-2; covid-19; data; effects; experience; groups; health; infection; interventions; media; need; pandemic; people; priorities; research; risk; sars; suicide; wellbeing
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        item: #1917 of 7819
          id: cord-273930-4asx0dq3
      author: Ortiz-Martínez, Yeimer
       title: Pericarditis in a young internal medicine resident with COVID-19 in Colombia
        date: 2020-08-28
       words: 758
      flesch: 44
     summary: but each author must sign) Anosmia in a healthcare worker with COVID-19 in Madrid, Spain Risk of SARS-CoV-2 transmission by aerosols, the rational use of masks, and protection of healthcare workers from COVID-19 Cardiac involvement in COVID-19 patients: Risk factors, predictors, and complications: A review Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis Acute pericarditis secondary to COVID-19 Coronavirus Disease 2019-COVID-19 Although cardiovascular conditions have been reported widely in COVID-19 so far [3, 4] , there is a lack of cases presenting with pericarditis, especially without other significant complications.
    keywords: case; covid-19; pericarditis
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        item: #1918 of 7819
          id: cord-273965-ma1rwkdq
      author: Omonzejele, Peter F.
       title: Preserving Bodily Integrity of Deceased Patients From the Novel SARS-CoV-2 Pandemic in West Africa
        date: 2020-11-09
       words: 3077
      flesch: 56
     summary: Since this is the most probable case for escapes from isolation centres, governments in the West African region should, perhaps, engage with the WHO to seek technical expertise in the decontamination of deceased people from COVID-19 isolation centres, and then make such corpses available to their families for traditional burial rites. This is the most probable reason patients continue to escape from COVID-19 isolation centres.
    keywords: african; burial; centres; covid-19; isolation; rites; west
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        item: #1919 of 7819
          id: cord-273968-ym79axlo
      author: Di Renzo, Gian Carlo
       title: COVID-19 in Pregnancy: Consider Thromboembolic Disorders and Thromboprophylaxis
        date: 2020-04-22
       words: 392
      flesch: 26
     summary: In non-pregnant patients admitted to the intensive care unit with COVID-19 pneumonia, the frequency of venous thromboembolic disorders is 25% (20/81) ascertained by ultrasound examination of the lower extremities (1). In another series of 184 patients with proven COVID-19 pneumonia, 31% had venous or arterial thromboembolism (defined as acute pulmonary embolism, ischemic stroke, deep vein thrombosis, or myocardial infarction) (2) .
    keywords: covid-19; patients
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        item: #1920 of 7819
          id: cord-273998-e7m5g242
      author: Que, Jianyu
       title: Psychological impact of the COVID-19 pandemic on healthcare workers: a cross-sectional study in China
        date: 2020-06-14
       words: 4866
      flesch: 38
     summary: key: cord-273998-e7m5g242 authors: Que, Jianyu; Shi, Le; Deng, Jiahui; Liu, Jiajia; Zhang, Li; Wu, Suying; Gong, Yimiao; Huang, Weizhen; Yuan, Kai; Yan, Wei; Sun, Yankun; Ran, Maosheng; Bao, Yanping; Lu, Lin title: Psychological impact of the COVID-19 pandemic on healthcare workers: a cross-sectional study in China date: 2020-06-14 journal: Gen Psychiatr DOI: 10.1136/gpsych-2020-100259 sha: doc_id: 273998 cord_uid: e7m5g242 BACKGROUND: Healthcare workers fighting against the coronavirus disease 2019 (COVID-19) pandemic are under tremendous pressure, which puts them at an increased risk of developing psychological problems. This study aimed to investigate the prevalence of psychological problems in different healthcare workers (ie, physicians, medical residents, nurses, technicians and public health professionals) during the COVID-19 pandemic in China and explore factors that are associated with the onset of psychological problems in this population during this public health crisis.
    keywords: anxiety; covid-19; healthcare; insomnia; line; pandemic; problems; workers
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        item: #1921 of 7819
          id: cord-274007-zndtddty
      author: Rasmussen, Sonja A.
       title: Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know
        date: 2020-02-24
       words: 5921
      flesch: 46
     summary: Available at: https:// Expert Review ajog.org www.who.int/emergencies/diseases/novelcoronavirus-2019 Severe acute respiratory syndrome-related coronavirus: the species and its viruses-a statement of the Coronavirus Study Group Severe acute respiratory syndrome: Historical, epidemiologic, and clinical features the role of superspreaders in infectious disease Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome Infants born to mothers with severe acute respiratory syndrome SARS in newborns and children Emergency cesarean section in an epidemic of the middle east respiratory syndrome: a case report A casecontrolled study comparing clinical course and outcomes of pregnant and non-pregnant women with severe acute respiratory syndrome SARS and pregnancy: a case report SARS during pregnancy, United States Severe acute respiratory syndrome in pregnancy Specific immunoglobulin g antibody detected in umbilical blood and amniotic fluid from a pregnant woman infected by the coronavirus associated with severe acute respiratory syndrome Possible central nervous system infection by SARS coronavirus The effect of Severe Acute Respiratory Syndrome on a hospital obstetrics and gynaecology service Managing obstetrical patients during severe acute respiratory syndrome outbreak First confirmed cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in the United States, updated information on the epidemiology of MERS-CoV infection, and guidance for the public, clinicians, and public health authorities Middle East respiratory syndrome (MERS) For severe acute respiratory syndrome, the largest series of 12 pregnancies had a case-fatality rate of 25%.
    keywords: cases; coronavirus; covid-19; infection; mers; patients; pregnancy; sars; syndrome; transmission; women
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        item: #1922 of 7819
          id: cord-274008-p3st70u3
      author: Mann, E. R.
       title: Longitudinal immune profiling reveals distinct features of COVID-19 pathogenesis
        date: 2020-06-16
       words: 6008
      flesch: 44
     summary: This is the first detailed longitudinal analysis of COVID-19 patients of varying severity and outcome, revealing common features and aspects that track with severity. This is the first detailed longitudinal analysis of COVID-19 patients of varying severity and outcome, revealing common features and aspects that track with severity.
    keywords: admission; blood; cells; covid-19; data; disease; figure; immune; medrxiv; monocytes; patients; preprint; severity
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        item: #1923 of 7819
          id: cord-274018-x50yiq10
      author: Gemici, Cengiz
       title: Covid-19 outbreak in a major radiation oncology department; which lessons should be taken?
        date: 2020-04-06
       words: 937
      flesch: 45
     summary: They also recommended that radiation oncology staff should not be given to Covid-19 treatment services if possible. Therefore, some of the staff in radiation oncology should be strictly reserved in clean area for the continuation of radiotherapy service for the safety of cancer patients.
    keywords: oncology; patients; radiation
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        item: #1924 of 7819
          id: cord-274027-ovdhnajp
      author: Gyasi, Razak M.
       title: Rethinking the Gendered Dimensions in the Impacts and Response to COVID-19 Pandemic
        date: 2020-06-11
       words: 1335
      flesch: 37
     summary: The World Health Organization Ebola, gender and conspicuously invisible women in global health governance Fighting COVID-19: Fear and internal conflict among older adults in Ghana Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Sex Hormones and Gender Role Relate to Gray Matter Volumes in Sexually Dimorphic Brain Areas Sex Drives Dimorphic Immune Responses to Viral Infections Prevalence and patterns of tobacco smoking among Chinese adult men and women: findings of the 2010 national smoking survey Explaining the gender gap in health services use in Ghanaian community-dwelling older cohorts Gender equity in the health work force: Analysis of 104 countries Serological evidence of Flavivirus circulation in human populations in Northern Kenya: an assessment of disease risk 2016-2017 A gendered human rights analysis of Ebola and Zika: locating gender in global health emergencies Overcoming the 'tyranny of the urgent': integrating gender into disease outbreak preparedness and response Executive Board EB146/Conf/17: strengthening preparedness for health emergencies; implementation of International Health Regulations Preparedness and vulnerability of African countries against importations of COVID-19: a modelling study None Strategic plans for preparedness must be fully grounded in strong gender analysis in the remit of gender roles and norms, and strengthen the leadership and resourceful participation of women in the decision-making process toward addressing COVID-19 outbreak.
    keywords: covid-19; health; response; women
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        item: #1925 of 7819
          id: cord-274043-ifr0oo7u
      author: Rozzini, Renzo
       title: The COVID Grim Reaper
        date: 2020-05-08
       words: 161
      flesch: 45
     summary: The COVID Grim Reaper Author: Head, Geriatric Dept Reference 23 COVID-19 in Italy: Ageism and Decision Making in a Pandemic The geriatrician: the frontline specialist in the treatment of 26 covid-19 patients -Gemelli against COVID-19 Geriatrics Team key: cord-274043-ifr0oo7u authors: Rozzini, Renzo title: The COVID Grim Reaper date: 2020-05-08 journal: J Am Med Dir Assoc DOI: 10.1016/j.jamda.2020.05.001 sha: doc_id: 274043 cord_uid: ifr0oo7u nan
    keywords: version
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        item: #1926 of 7819
          id: cord-274053-406dfdih
      author: Srivastava, Kamna
       title: Association between COVID-19 and cardiovascular disease
        date: 2020-07-14
       words: 2583
      flesch: 35
     summary: COVID-19 patients with pre-existing heart disease may suffer a heart attack or develop congestive heart failure. Identifier: NCT04312009 Sick sinus syndrome induced by interferon and ribavirin therapy in a patient with chronic hepatitis C Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Altered lipid metabolism in recovered SARS patients twelve years after infection Sex differences in the aging pattern of renin-angiotensin system serum peptidases Incidence of thrombotic complications in critically ill ICU patients with COVID-19
    keywords: ace2; angiotensin; coronavirus; cov-2; covid-19; heart; patients; sars
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        item: #1927 of 7819
          id: cord-274100-0d2u23nv
      author: Rochon, Paula A.
       title: The Missing Pieces of the COVID‐19 Puzzle
        date: 2020-06-23
       words: 1093
      flesch: 57
     summary: By laying out this information and linking it to confirmed COVID-19 cases and deaths, patterns emerge to help put this COVID-19 puzzle together. Their respective government websites were explored to obtain confirmed COVID-19 cases and fatalities, disaggregated by sex and age.
    keywords: age; covid-19; sex
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        item: #1928 of 7819
          id: cord-274121-3w6kc0c9
      author: Ramiro, Sofia
       title: Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm syndrome: results of the CHIC study
        date: 2020-07-20
       words: 5784
      flesch: 43
     summary: Control patients with COVID-19-associated CSS (same definition) were retrospectively sampled from the pool of patients (n=350) admitted between 7 March and 31 March, and matched one to one to treated patients on sex and age. control patients with coVid-19-associated css (same definition) were retrospectively sampled from the pool of patients (n=350) admitted between 7 march and 31 march, and matched one to one to treated patients on sex and age.
    keywords: care; control; covid-19; css; fees; group; hospital; mortality; patients; study; treatment; ventilation
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        item: #1929 of 7819
          id: cord-274141-vujx538o
      author: Chinsembu, Kazhila C.
       title: Coronaviruses and Nature’s Pharmacy for the Relief of Coronavirus Disease 2019
        date: 2020-10-06
       words: 11364
      flesch: 42
     summary: Evid Based In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds Binding interaction of quercetin-3-βgalactoside and its synthetic derivatives with SARS-CoV 3CL pro : structure-activity relationship studies reveal salient pharmacophore features A report of clinical diagnosis and treatment of nine cases of coronavirus disease 2019 Statistical evidence for the usefulness of Chinese medicine in the treatment of SARS Antiviral effects of saikosaponins on human coronavirus 229E in vitro Plants as antimalarial agents in Sub-Saharan Africa Green Medicines: pharmacy of natural products for HIV and five AIDS-related infections Chemical diversity and activity profiles of HIV-1 reverse transcriptase inhibitors from plants Evaluation of antiviral activities of Houttuynia cordata Thunb. Learning from the experience of using supplementary treatment with Chinese medicine on SARS or SARS-like infectious disease in 2003 The lesson of supplementary treatment with Chinese medicine on severe laboratory-confirmed SARS patients SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells Applications of the phytomedicine Echinacea purpurea (purple coneflower) in infectious diseases Inhibitory activities of Cassia tora and its anthraquinone constituents on angiotensin-converting enzyme Ginseng, the natural effectual antiviral: protective effects of Korean red ginseng against viral infection Natural products and their derivatives against coronavirus: a review of the non-clinical and pre-clinical data cytotoxicity and active compound of Pechuel-loeschea leubnitziae O. Hoffm.
    keywords: 2019; 3cl; activity; anti; antiviral; compounds; coronavirus; cov; cov-2; covid-19; drug; entry; et al; hcov; human; infection; inhibitors; medicinal; plants; pro; products; protein; replication; sars; tcm; treatment
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        item: #1930 of 7819
          id: cord-274147-jvymoene
      author: Collins, Obiora C.
       title: Estimating the impact of lock-down, quarantine and sensitization in a COVID-19 outbreak: lessons from the COVID-19 outbreak in China
        date: 2020-09-17
       words: 2663
      flesch: 52
     summary: Using all the data up to 30 March resulted in an R 0 > 1, confirming that the control measures implemented in China were effective in COVID-19 control and, where possible, should be implemented in other countries. This decrease was due to the implementation of effective control measures, including: public education on disease prevention and environmental hygiene; installation of infra-red thermometers in airports, railway stations, etc. to detect infectious Mathematical models have been successfully used in studying the dynamics of infectious disease outbreaks (Hellewell et al., 2020; Balilla, 2020; Li et al., 2020; Kucharski et al., 2020; Mukandavire et al., 2011; Collins & Duffy, 2018; Collins & Govinder, 2014; Tian et al., 2020; Mukandavire, Smith & Morris Jr, 2013; Tuite et al., 2011 ).
    keywords: control; covid-19; model; outbreak; rate
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        item: #1931 of 7819
          id: cord-274150-ukdha3ap
      author: Choi, Jun Yong
       title: Convalescent Plasma Therapy for Coronavirus Disease 2019
        date: 2020-09-03
       words: 3166
      flesch: 36
     summary: Because historical experience of the use of convalescent plasma therapy suggests that the neutralizing activity may correlate with the efficacy of convalescent plasma, the measurement of SARS-CoV-2 neutralizing antibody titers should be considered, if available. The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis Ebola virus disease: An emerging and re-emerging viral threat West Nile virus neutralization by US plasma-derived immunoglobulin products The convalescent sera option for containing COVID-19 Meta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment? Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection Evaluation of convalescent whole blood for treating Ebola virus disease in Evaluation of convalescent plasma for Ebola virus disease in Guinea Use of convalescent plasma therapy in SARS patients in Hong Kong Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience Convalescent plasma transfusion for the treatment of COVID-19: Systematic review Convalescent plasma in Covid-19: Possible mechanisms of action Plasma therapy against infectious pathogens, as of yesterday, today and tomorrow Effectiveness of convalescent plasma therapy in severe COVID-19 patients Treatment of 5 critically ill patients with COVID-19 with convalescent plasma Treatment with convalescent plasma for critically ill patients with severe acute respiratory syndrome coronavirus 2 infection Use of convalescent plasma therapy in two COVID-19 patients with acute respiratory distress syndrome in Korea Effect of convalescent plasma therapy on viral shedding and survival in patients with coronavirus disease 2019 Treatment of coronavirus disease 2019 (COVID-19) patients with convalescent plasma Covid-19 plasma task force.
    keywords: convalescent; covid-19; disease; patients; plasma; therapy; treatment
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        item: #1932 of 7819
          id: cord-274163-yxl9a9u7
      author: Yadav, Uday Narayan
       title: A Syndemic Perspective on the Management of Non-communicable Diseases Amid the COVID-19 Pandemic in Low- and Middle-Income Countries
        date: 2020-09-25
       words: 3761
      flesch: 36
     summary: On the other hand, there is a disruption of routine health services, such as screening and diagnosis, supplies of essential medicines, and access to health service providers and support services. The COVID-19 pandemic has escalated into a syndemic due to several driving factors, such as overcrowding, loneliness, uncertainty, poor nutrition, and lack of access to health services; consequently, depression, suicide, domestic violence, and psychiatric illnesses have significantly increased (11) .
    keywords: countries; covid-19; health; healthcare; lmics; pandemic; plwncds; services; syndemic
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        item: #1933 of 7819
          id: cord-274182-7z2tb0ll
      author: Veerabathini, Bala C
       title: An Unusual Case of Moraxella osleonsis Bacteremia in an Immunocompetent Patient With SARS-CoV-2 Infection
        date: 2020-08-31
       words: 1886
      flesch: 43
     summary: Ex vivo transplantation of polyclonal Tregs as well as allogeneic HLA-matched umbilical cord-derived Tregs have shown some positive results in COVID-19 patients [19] . Current therapies for COVID-19 have varied, and further understanding of T cell regulation in COVID-19 patients may provide more robust treatments in the future.
    keywords: bacteremia; cells; covid-19
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        item: #1934 of 7819
          id: cord-274184-hm516x6p
      author: Elli, Luca
       title: Endoscopy during the Covid-19 outbreak: experience and recommendations from a single center in a high-incidence scenario
        date: 2020-04-27
       words: 4847
      flesch: 44
     summary: To face the new scenario all the hospitals have been re-organised in order to reduce all the outpatient services and to devote almost all their personnel and resources to the management of Covid-19 patients. Establishing maximum prevention within the endoscopy unit is a necessary countermeasure to the large spectrum of signs and symptoms expressed by Covid-19 patients (fever, cough but also, in smaller percentages, nausea, vomiting, diarrhoea and even neurological symptoms) and the large quantity of asymptomatic carriers [1, 2, 27, 28] .
    keywords: coronavirus; cov-2; covid-19; endoscopy; infection; outbreak; patients; pcr; risk; route; sars
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        item: #1935 of 7819
          id: cord-274199-3stjueja
      author: Baldi, Enrico
       title: COVID-19 kills at home: the close relationship between the epidemic and the increase of out-of-hospital cardiac arrests
        date: 2020-06-20
       words: 4313
      flesch: 38
     summary: Pulmonary embolism in COVID-19 patients: awareness of an increased prevalence Reduced rate of hospital admissions for ACS during Covid-19 outbreak in Northern Italy Impacto de la pandemia de COVID-19 sobre la actividad asistencial en cardiología intervencionista en España Reduction in STsegment elevation cardiac catheterization laboratory activations in the United States during COVID-19 pandemic Primary coronary angioplasty compared with intravenous thrombolytic therapy for acute myocardial infarction: six-month follow up and analysis of individual patient data from randomized trials Covid-19-the law and limits of quarantine Characteristics of COVID-19 patients dying in Italy Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period We would like to thank all the Lombardia CARe researchers and all the EMS personnel. In addition, digestive symptoms (i.e. diarrhoea and vomiting) are present in a fair number of COVID-19 patients, especially in those with mild disease severity, with a delayed diagnosis and treated at home, 32 and they were also experienced by 7% of the suspected or diagnosed COVID-19 patients in our cohort.
    keywords: 2019; cardiac; covid-19; ems; epidemic; incidence; increase; ohca; patients
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        item: #1936 of 7819
          id: cord-274203-urqed43m
      author: Katal, Sanaz
       title: Chest-CT findings of COVID-19 in patients with pre-existing malignancies; a pictorial review
        date: 2020-06-09
       words: 2339
      flesch: 33
     summary: The differential diagnosis of pulmonary infiltrates in cancer patients during the outbreak of the 2019 novel coronavirus disease Like other malignancies, breast cancer patients are in lower immune status and prone to adverse reactions, such as leukopenia and other treatment-related complications during the course of chemotherapy.
    keywords: cancer; covid-19; disease; infection; patients
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        item: #1937 of 7819
          id: cord-274230-old0xmcc
      author: Zhao, Qianwen
       title: Lymphopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A systemic review and meta-analysis
        date: 2020-05-04
       words: 870
      flesch: 33
     summary: Mean difference (MD) of lymphocyte count in COVID-19 patients with or without severe disease and odds ratio (OR) of lymphopenia for severe form of COVID-19 was evaluated with this meta-analysis. The pooled analysis showed that lymphocyte count was significantly lower in severe COVID-19 patients (MD -0.31×109/L; 95%CI: -0.42 to -0.19×109/L).
    keywords: coronavirus; covid-19; patients
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        item: #1938 of 7819
          id: cord-274250-95yzt1gj
      author: Mortaz, Esmaeil
       title: Silent hypoxia: higher NO in red blood cells of COVID-19 patients
        date: 2020-10-16
       words: 2719
      flesch: 42
     summary: There is no evidence that direct oxygen therapy is beneficial in the management of breathlessness in severe COVID-19 patients but our data suggests that NO therapy may be beneficial in COVID-19 patients with hypoxia [23] . Whether higher levels of intracellular NO inside RBC of COVID-19 infected patients drive the unexpected silent hypoxia phenotype needs to be examined in future clinical studies using NO donors in hypoxemic COVID-19 patients.
    keywords: blood; covid-19; hypoxia; intracellular; levels; oxygen; patients; rbc
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        item: #1939 of 7819
          id: cord-274251-2x1nltpn
      author: Doran, S.L.F.
       title: COVID-19 infection in patients following hepato-pancreatico-biliary intervention: An early experience
        date: 2020-04-28
       words: 652
      flesch: 40
     summary: key: cord-274251-2x1nltpn authors: Doran, S.L.F.; Patel, P.H.; Chaudry, A.; Pollok, J.M.; Pollok, J.M.; Kumar, S.; Bhogal, R.H. title: COVID-19 infection in patients following hepato-pancreatico-biliary intervention: An early experience date: 2020-04-28 journal: Eur J Surg Oncol DOI: 10.1016/j.ejso.2020.04.045 sha: doc_id: 274251 cord_uid: 2x1nltpn nan The risk to patients undergoing cancer surgery during the coronavirus disease (COVID-19) pandemic is not known. Patient 1 received neoadjuvant FOLFIRINOX chemotherapy for a borderline resectable ampullary adenocarcinoma followed by a pylorus preserving pancreaticoduodenectomy with partial superior mesenteric vein resection.
    keywords: covid-19; patient
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        item: #1940 of 7819
          id: cord-274264-s477tw3x
      author: Shen, M.
       title: Projected COVID-19 epidemic in the United States in the context of the effectiveness of a potential vaccine and implications for social distancing and face mask use
        date: 2020-10-30
       words: 4127
      flesch: 47
     summary: key: cord-274264-s477tw3x authors: Shen, M.; Zu, J.; Fairley, C. K.; Pagan, J. A.; An, L.; Du, Z.; Guo, Y.; Rong, L.; Xiao, Y.; Zhuang, G.; Li, Y.; Zhang, L. title: Projected COVID-19 epidemic in the United States in the context of the effectiveness of a potential vaccine and implications for social distancing and face mask use date: 2020-10-30 journal: nan DOI: 10.1101/2020.10.28.20221234 sha: doc_id: 274264 cord_uid: s477tw3x Background: Multiple candidates of COVID-19 vaccines have entered Phase III clinical trials in the United States (US). The findings from this study can inform the planned rollout of COVID-19 vaccines and the continued implementation of non-pharmaceutical interventions such as social distancing and mask use mandates. .
    keywords: coverage; covid-19; effectiveness; face; mask; vaccine
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        item: #1941 of 7819
          id: cord-274268-0ucqp3uz
      author: Chorus, Caspar
       title: Diabolical dilemmas of COVID-19: An empirical study into Dutch society’s trade-offs between health impacts and other effects of the lockdown
        date: 2020-09-16
       words: 7804
      flesch: 40
     summary: Returning to the fact that our sample, while representative in terms of gender and age, is somewhat skewed towards highly educated people (see Table 2 ), these segment-specific estimation results imply that our aggregate level estimates for society's weighing of various policy impacts of exit strategies is likely to somewhat underestimate the weight attached to fatalities and to somewhat overestimate the weight attached to other policy impacts such as physical and mental injuries, educational advantage, and income loss. With a view to exploring potential causes behind differences in weights attached to fatalities and other policy impacts, we estimated a series of two-class latent class models, where class membership was determined by respondents' perceived risk that they or a relative would contract COVID-19, would become severely ill if having contracted the virus, would be hospitalized if contracting the virus, or would die if contracting the virus.
    keywords: choice; class; covid-19; dutch; effects; health; impacts; model; number; policies; policy; respondents; terms
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        item: #1942 of 7819
          id: cord-274282-hvx5m2bx
      author: Liu, Yang
       title: Association between ages and clinical characteristics and outcomes of coronavirus disease 2019
        date: 2020-04-27
       words: 1543
      flesch: 45
     summary: However, the ages related clinical characteristics, diseases courses and outcomes other than death in COVID-19 patients remain unclear. This is the first study to systematically evaluate the impact of age on the clinical characteristics and important outcomes for COVID-19 patients, thus helping clinicians to establish risk stratification of COVID-19 patients as early as possible.
    keywords: covid-19; disease; patients; study
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        item: #1943 of 7819
          id: cord-274283-ukhgs6z1
      author: Goel, Sunny
       title: Clinical Characteristics and In-Hospital Mortality for COVID-19 Across The Globe
        date: 2020-07-18
       words: 1999
      flesch: 31
     summary: Washington Risk of QT interval prolongation associated with use of hydroxychloroquine with or without concomitant azithromycin among hospitalized patients testing positive for coronavirus disease Characteristics of hospitalized adults with COVID-19 in an integrated health care system in California Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: a single center study Initial experiences from patients with COVID-19 on ventilatory support in Denmark Prevalence and characteristics of gastrointestinal symptoms in patients with SARS-CoV-2 Infection in the United States: a multicenter cohort study Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York city area High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation Clinical impact of renin-angiotensin system inhibitors on in-hospital mortality of patients with hypertension hospitalized for COVID-19 Clinical features and treatment of COVID-19 patients in northeast Chongqing Suppressed T cellmediated immunity in patients with COVID-19: a clinical retrospective study in Wuhan Clinical characteristics and imaging manifestations of the 2019 novel coronavirus disease (COVID-19): a multi-center study in Wenzhou city Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore Analysis of clinical characteristics and laboratory findings of 95 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a retrospective analysis Risk factors for disease severity, unimprovement, and mortality in COVID-19 patients in Wuhan. Apart from cardiovascular diseases, respiratory conditions [lung disease, COPD, or asthma], CKD, and immunosuppression/HIV were also prevalent among COVID-19 patients.
    keywords: characteristics; covid-19; hospital; mortality; patients
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        item: #1944 of 7819
          id: cord-274284-mi4n7xty
      author: Pang, Khang Wen
       title: Frequency and Clinical Utility of Olfactory Dysfunction in COVID-19: a Systematic Review and Meta-analysis
        date: 2020-10-13
       words: 4406
      flesch: 43
     summary: To investigate the estimated frequency of OD amongst COVID-19 patients, meta-analysis B included studies if they described the frequency of OD in COVID-19 positive patients and if smell tests were performed or if OD symptoms were explicitly asked in questionnaires or interviews. With reference to Fig. 4 , the overall pooled frequency of OD amongst COVID-19 patients was 0.56 (0.47 to 0.64).
    keywords: covid-19; dysfunction; frequency; olfactory; patients; smell; studies; study; symptoms
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        item: #1945 of 7819
          id: cord-274313-mrvk9r4w
      author: Li, Hui
       title: SARS-CoV-2 and viral sepsis: observations and hypotheses
        date: 2020-04-17
       words: 2434
      flesch: 36
     summary: Diagnosis and treatment of novel coronavirus pneumonia in China A pathological report of three COVID-19 cases by minimally invasive autopsies A novel coronavirus from patients with pneumonia in China Detection of SARS-CoV-2 in different types of clinical specimens A pneumonia outbreak associated with a new coronavirus of probable bat origin Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. 8, 9 SARS-CoV-2 infectious virus particles have been isolated from respiratory samples, 10 as well as from faecal 11 and urine (Zhao J, Guangzhou Medical University, personal communication) specimens from COVID-19 patients, suggesting that multiple organ dysfunction in severe COVID-19 patients is at least partially caused by a direct attack from the virus.
    keywords: coronavirus; cov-2; covid-19; infection; patients; sars
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        item: #1946 of 7819
          id: cord-274324-obhrbxu4
      author: Tian, Wenjie
       title: Predictors of mortality in hospitalized COVID‐19 patients: A systematic review and meta‐analysis
        date: 2020-05-22
       words: 3022
      flesch: 42
     summary: Accepted Article cerebrovascular disease, diabetes, chronic renal disease, smoking history, COPD) between COVID-19 patients who survived and those who did not survive. For laboratory data (i.e. continuous measures) we calculated weighted mean differences (WMD) and 95% confidence intervals (95% CI) in COVID-19 patients who survived versus those who did not survive whenever two or more studies reported a given parameter.
    keywords: analysis; covid-19; disease; meta; mortality; patients; risk; studies
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        item: #1947 of 7819
          id: cord-274326-msbdrp3e
      author: Ren, Xiaohan
       title: Multiple Expression Assessments of ACE2 and TMPRSS2 SARS-CoV-2 Entry Molecules in the Urinary Tract and Their Associations with Clinical Manifestations of COVID-19
        date: 2020-11-04
       words: 4907
      flesch: 39
     summary: Also, IHC results revealed that ACE2 was overexpressed in kidney tubule cells, as well as seminiferous duct cells and Leydig cells in the testis (Figure 2A -B). Elevated levels of staining for TMPRSS2 were observed in kidney tubule cells ( Figure 2C ).
    keywords: ace2; cells; cov-2; covid-19; expression; figure; human; infection; kidney; patients; sars; testis; tmprss2
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        item: #1948 of 7819
          id: cord-274328-ea1ehsnq
      author: Assaker, Rita
       title: Presenting symptoms of COVID-19 in children: a meta-analysis of published studies
        date: 2020-05-31
       words: 728
      flesch: 41
     summary: Asymptomatic patients have been estimated to represent 85% of infected patients in the general population (6) , and a recent study in pregnant women found 13.5 % of asymptomatic patients with a positive RT-qPCR test (7) . Once the peak of COVID-19 cases has passed, delayed medical and surgical care will become a priority.
    keywords: covid-19; patients; sars
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        item: #1949 of 7819
          id: cord-274339-gj9wjkoo
      author: Swanson, D. A.
       title: A Simple Method for Estimating the Number of Unconfirmed COVID-19 Cases in a Local Area that Includes a Confidence Interval: A Case Study of Whatcom County, Washington
        date: 2020-05-05
       words: 2061
      flesch: 52
     summary: Recall the ratio of estimated unconfirmed cases to confirmed cases shown earlier, (Ui/Ci), where (Ui/Ci) = 9.4 = 4,639,790/492,416. Once R is found, it can be used to estimate the number of positive, unconfirmed cases, Ui, for a given area, i, by dividing it into the reported deaths due to COVID-19 in area i, Di As we illustrate below, once Ui is estimated, we also can find the ratio of unconfirmed cases (Ui) to confirmed cases (Ci) , viz., ratio = Ui/ Ci This ratio is useful, first, because we can use it to estimate the number of unconfirmed cases in a given area of interest, w (Uw), by multiplying it by the confirmed cases in area w, Cw .
    keywords: cases; estimate; number
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        item: #1950 of 7819
          id: cord-274343-y9zqbefu
      author: Petersen, Irene
       title: Three Quarters of People with SARS-CoV-2 Infection are Asymptomatic: Analysis of English Household Survey Data
        date: 2020-10-08
       words: 2198
      flesch: 50
     summary: We evaluated the value of COVID-19 symptoms as a marker for SARS-CoV-2 infection from a representative English survey. We estimated sensitivity, specificity, the proportion of asymptomatic cases (1 – sensitivity), positive predictive value (PPV) and negative predictive value (NPV) of COVID-19 symptoms as a marker of infection using results of the SARS-CoV-2 test as the “gold standard”.
    keywords: covid-19; sars; symptoms; test
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        item: #1951 of 7819
          id: cord-274353-tzlcpx7q
      author: McDermott, Amy
       title: Inner Workings: Molecular biologists offer “wartime service” in the effort to test for COVID-19
        date: 2020-05-05
       words: 1989
      flesch: 41
     summary: Institutions with medical centers, such as the University of Washington, have the advantage of large clinical labs and some certified medical laboratory scientists onsite, meaning they can, in fact, legally and appropriately pivot into COVID-19 testing centers. Even so, the urgency of the pandemic has spurred some states to relax legal restrictions on who can perform COVID-19 testing.
    keywords: centers; covid-19; laboratory; researchers; testing; university
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        item: #1952 of 7819
          id: cord-274368-s1h3p5s9
      author: Carter, B.
       title: Nosocomial COVID-19 infection: examining the risk of mortality. The COPE-Nosocomial study (COVID in Older PEople).
        date: 2020-07-21
       words: 3462
      flesch: 47
     summary: These wards solely managed suspected or confirmed COVID-19 patients. There is an urgent need for clarity regarding patients who acquire COVID-19 in hospital (nosocomial COVID-19 infection [NC]), their risk of mortality, compared to those with community acquired COVID-19 (CAC) infection.
    keywords: admission; covid-19; hospital; infection; mortality; patients; study
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        item: #1953 of 7819
          id: cord-274416-bmvazgj7
      author: Trevisanuto, Daniele
       title: Neonatal Resuscitation Where the Mother Has a Suspected or Confirmed Novel Coronavirus (SARS-CoV-2) Infection: Suggestion for a Pragmatic Action Plan
        date: 2020-04-24
       words: 3769
      flesch: 45
     summary: Lancet Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn A case report of neonatal COVID-19 infection in China Neonati ricoverati con infezione sospetta o accertata da SARS-CoV-2. Urgent questions that need to be addressed promptly include whether pregnant women who have confirmed COVID-19 infection are more likely to experience lifethreatening events, and whether SARS-CoV-2 could spread vertically and pose risks to the fetus and neonate [12, 13] .
    keywords: coronavirus; cov-2; covid-19; delivery; disease; infection; mother; neonatal; sars
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        item: #1954 of 7819
          id: cord-274443-r6ponjr4
      author: Lawson, Monica
       title: Child Maltreatment during the COVID-19 Pandemic: Consequences of Parental Job Loss on Psychological and Physical Abuse Towards Children
        date: 2020-09-04
       words: 6923
      flesch: 35
     summary: Preliminary results from the recent recession using state level data The relationship between unemployment and child maltreatment: A county-level perspective in California The CES-D scale: A self-report depression scale for research in the general population Income inequality and child maltreatment risk during economic recession Local job losses and child maltreatment: The importance of community context The Great Recession and risk for child abuse and neglect Fourth National Incidence Study of Child Abuse and Neglect (NIS-4): Report to Congress. In particular, the The stress and coping model of child maltreatment indicates that the impact of life stressors on a parents' propensity for committing child abuse depends on their dispositional coping strategies (Hillson & Kuiper, 1994) .
    keywords: abuse; children; covid-19; covid-19 pandemic; job; loss; maltreatment; pandemic; parents
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        item: #1955 of 7819
          id: cord-274448-lzxhtnfi
      author: Chua, Alfredo
       title: Changing the Landscape of Medical Oncology Training at the National University Hospital in the Philippines during the Coronavirus Disease 2019 (COVID-19) Pandemic
        date: 2020-06-05
       words: 1656
      flesch: 41
     summary: Emphasis was given on the important considerations in the management of cancer patients during the COVID-19 pandemic. During discussions, emphasis was given on the important considerations in the management of cancer patients during the COVID-19 pandemic.
    keywords: covid-19; pandemic; patients; training
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        item: #1956 of 7819
          id: cord-274459-781by93r
      author: Khalifa, Shaden A. M.
       title: Comprehensive Overview on Multiple Strategies Fighting COVID-19
        date: 2020-08-11
       words: 5470
      flesch: 48
     summary: On 9 June 2020, the Ministry of Health and Family Welfare (MoHFW) announced that 266,598 confirmed COVID-19 cases and 7471 deaths from 32 states especially the states of Maharashtra, Tamil Nadu, Delhi, and Gujarat. An intensified surveillance system was developed to monitor COVID-19 cases between hospital and primary care pneumonia patients.
    keywords: care; cases; china; coronavirus; countries; covid-19; disease; government; health; pandemic; people; public; transmission
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        item: #1957 of 7819
          id: cord-274470-82nhmusm
      author: Ricciardi, Gabriella
       title: Go back to the basics: Cardiac surgery residents at the time of COVID‐19
        date: 2020-06-05
       words: 1303
      flesch: 51
     summary: For example, coronary artery disease showed a higher mortality rate in patients affected by COVID-19, but it's, however, reasonable to think that all the cardiac pathologies affecting the lung circulation-such as symptomatic severe mitral diseases or aortic stenosis-might deserve a priority access to treatment, to increase the survival rate in case of an acquired-Coronavirus infection later on. Eventually, due to the inhospital risk of disease transmission, the number of working doctors has been restricted and some providers have been moved to hospital areas in dire need of physicians experienced in caring for critically ill patients.
    keywords: covid-19; patients; surgery; time
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        item: #1958 of 7819
          id: cord-274481-k1dp1ilv
      author: Falavigna, Maicon
       title: Guidelines for the pharmacological treatment of COVID-19. The task-force/consensus guideline of the Brazilian Association of Intensive Care Medicine, the Brazilian Society of Infectious Diseases and the Brazilian Society of Pulmonology and Tisiology
        date: 2020
       words: 6979
      flesch: 33
     summary: COVID-19 Treatment Guidelines Zhejiang Da Xue Xue Bao Yi Xue Ban Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: openlabel, randomized, controlled trial Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial Outcomes of hydroxychloroquine usage in United States veterans hospitalized with Covid-19 Observational study of hydroxychloroquine in hospitalized patients with Covid-19 Risk of QT interval prolongation associated with use of hydroxychloroquine with or without concomitant azithromycin among hospitalized patients testing positive for coronavirus disease 2019 (COVID-19) Effect of high vs low doses of chloroquine diphosphate as adjunctive therapy for patients hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: a randomized clinical trial Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: a pilot observational study Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: a retrospective analysis of 1061 cases in Marseille, France A pilot study of hydroxychloroquine in treatment of patients with moderate COVID-19. Zhejiang Da Xue Xue Bao Yi Xue Ban Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open-label, randomized, controlled trial Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Risk of QT interval prolongation associated with use of hydroxychloroquine with or without concomitant azithromycin among hospitalized patients testing positive for coronavirus disease 2019 (COVID-19) Observational study of hydroxychloroquine in hospitalized patients with Covid-19 Effect of high vs low doses of chloroquine diphosphate as adjunctive therapy for patients hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: a randomized clinical trial Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: a retrospective analysis of 1061 cases in Marseille, France Safety of hydroxychloroquine, alone and in combination with azithromycin, in light of rapid wide-spread use for COVID-19: a multinational, network cohort and self-controlled case series study Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: a pilot observational study No evidence of rapid antiviral clearance or clinical benefit with the combination of hydroxychloroquine and azithromycin in patients with severe COVID-19 infection The QT interval in patients with SARS-CoV-2 infection treated with hydroxychloroquine/ azithromycin Early description of coronavirus 2019 disease in kidney transplant recipients in New York Inpatient use of mobile continuous telemetry for COVID-19 patients treated with hydroxychloroquine and azithromycin.
    keywords: agents; azithromycin; coronavirus; covid-19; evidence; hydroxychloroquine; patients; recommendations; risk; studies; study; therapy; treatment; trials; use
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        item: #1959 of 7819
          id: cord-274491-921orhjg
      author: Chau, Vinh Q.
       title: The Imperfect Cytokine Storm: Severe COVID-19 with ARDS in Patient on Durable LVAD Support
        date: 2020-04-08
       words: 1476
      flesch: 41
     summary: Changes in the pattern of these laboratory markers may be reliable tool to follow LVAD patients with COVID-19. Biomarkers of COVID-19 related cytokine storm include lymphopenia, C-reactive protein, lactate dehydrogenase (LDH), ferritin, D-dimer, and troponin
    keywords: ards; covid-19; disease; lvad; patient; support
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        item: #1960 of 7819
          id: cord-274494-heu6rmbt
      author: Pablos, Jose L
       title: Prevalence of hospital PCR-confirmed COVID-19 cases in patients with chronic inflammatory and autoimmune rheumatic diseases
        date: 2020-06-12
       words: 3124
      flesch: 28
     summary: These data provide a basis to improve preventive recommendations to rheumatic patients and to analyse the specific factors involved in COVID-19 susceptibility. These data provide a basis to improve preventive recommendations to rheumatic patients and to analyse the specific factors involved in coVid-19 susceptibility.
    keywords: covid-19; disease; hospital; patients; population; prevalence; reference
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        item: #1961 of 7819
          id: cord-274498-fa16vl9i
      author: Ravioli, Svenja
       title: The syndrome of inappropriate antidiuresis in COVID-19 pneumonia: report of two cases
        date: 2020-05-17
       words: 1014
      flesch: 51
     summary: We describe the first two cases of the syndrome of inappropriate antidiuresis (SIADH) in patients with COVID-19 pneumonia. key: cord-274498-fa16vl9i authors: Ravioli, Svenja; Niebuhr, Norbert; Ruchti, Chantal; Pluess, Emanuel; Stoeckli, Thomas; Lindner, Gregor title: The syndrome of inappropriate antidiuresis in COVID-19 pneumonia: report of two cases date: 2020-05-17 journal: Clin Kidney J DOI: 10.1093/ckj/sfaa080 sha: doc_id: 274498 cord_uid: fa16vl9i
    keywords: cases; covid-19; pneumonia
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        item: #1962 of 7819
          id: cord-274503-9ccgcrvd
      author: Nasta, Amrit Manik
       title: Impact of COVID-19 on General Surgical Practice in India
        date: 2020-06-26
       words: 2159
      flesch: 45
     summary: COVID-19 has led to a drastic reduction in outpatient and elective surgical practices. COVID-19 has led to significant worldwide change in surgical practice.
    keywords: covid-19; lockdown; practice; surgeons; survey
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        item: #1963 of 7819
          id: cord-274510-fo7p98np
      author: Spadera, Lucrezia
       title: Potential Role of GcMAF in suppressing the severity of COVID-19-induced immune responses: lesson learned from HIV
        date: 2020-09-24
       words: 4060
      flesch: 35
     summary: Meanwhile, in COVID-19 patients, in addition to the reduced peripheral lymphocyte counts, mainly CD4 + T and CD8 + T cells, there were found significant high levels of pro-inflammatory cytokines and chemokines [2] [3] [4] [5] [6] [7] . What we postulated could also explain hypercoagulability with elevated concentrations of D-dimer, fibrin degradation products increase, PT and aPTT prolongation, observed in COVID-19 patients [37]
    keywords: actin; activity; cov-2; covid-19; dbp; gcmaf; lung; macrophage; patients; protein; vitamin
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        item: #1964 of 7819
          id: cord-274513-0biyfhab
      author: Baumgartner, M. T.
       title: Assessing the relative contributions of healthcare protocols for epidemic control: an example with network transmission model for COVID-19
        date: 2020-07-22
       words: 5079
      flesch: 37
     summary: Radiology The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study R: A language and environment for statistical computing Critical Supply Shortages -The Need for Ventilators and Personal Protective Equipment during the Covid-19 Pandemic The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak GEMFsim: A stochastic simulator for the generalized epidemic modeling framework Individual-based network model for Rift Valley fever in Kabale District Social distancing during the COVID-19 pandemic: Staying home save lives COVID-19 infection: the perspectives on immune responses Projecting demand for critical care beds during COVID-19 outbreaks in Canada Estimates of the severity of coronavirus disease 2019: a model-based analysis Urban mobility and neighborhood isolation in America's 50 largest cities Rational use of personal protective equipment for coronavirus disease ( COVID-19) and considerations during severe shortages Can we contain the COVID-19 outbreak with the same measures as for SARS? The increasing number of COVID-19 cases threatens human life and requires retainment actions that control the spread of the virus in the absence of effective medical therapy or a reliable vaccine.
    keywords: covid-19; distancing; et al; individual; infection; model; number; people; rate
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        item: #1965 of 7819
          id: cord-274517-9lewc581
      author: Litchman, Graham H.
       title: The Immediate Impact of COVID-19 on US Dermatology Practices
        date: 2020-05-16
       words: 669
      flesch: 51
     summary: The purpose of this study was to determine the magnitude of 33 the initial impact of COVID-19 on US dermatology outpatient care. 65 Our findings demonstrate the significant early impact of COVID-19 on US dermatologic care and can help 66 better understand national trends.
    keywords: covid-19; impact
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        item: #1966 of 7819
          id: cord-274521-u8p5lz9o
      author: Lee, Abby C.
       title: Tobacco, but Not Nicotine and Flavor-Less Electronic Cigarettes, Induces ACE2 and Immune Dysregulation
        date: 2020-07-31
       words: 5736
      flesch: 45
     summary: These results suggest that tobacco smokers may be more vulnerable to SARS-CoV-2 infection than e-cigarette smokers if infection susceptibility is based upon ACE2 abundance. The Kruskal-Wallis analysis test was applied to determine differential expression of ACE2 between e-cig users and non-e-cig users for both of these datasets (p < 0.05).
    keywords: cells; cig; cigs; covid-19; expression; flavor; nicotine; smokers; smoking; tobacco
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        item: #1967 of 7819
          id: cord-274542-fpzk5k79
      author: Patti, Giuseppe
       title: Questions and Answers on Practical Thrombotic Issues in SARS-CoV-2 Infection: A Guidance Document from the Italian Working Group on Atherosclerosis, Thrombosis and Vascular Biology
        date: 2020-11-03
       words: 5631
      flesch: 26
     summary: Bruxelles: European Society of Cardiology Efficacy of various treatment modalities for nCOV-2019: a systematic review and metaanalysis Swinging the pendulum: lessons learned from public discourse concerning hydroxychloroquine and COVID-19 Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture Treatment with lopinavir/ ritonavir or interferon-β1b improves outcome of MERSCoV infection in a nonhuman primate model of common marmoset Treatment of Middle East respiratory syndrome with a combination of lopinavirritonavir and interferon-β1b (MIRACLE trial): study protocol for a randomized controlled trial Post-exposure prophylaxis for Middle East respiratory syndrome in healthcare workers A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV Effectiveness of remdesivir for the treatment of hospitalized Covid-19 persons: a network meta-analysis Novel coronavirus treatment with ribavirin: groundwork for evaluation concerning COVID-19 Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19 Dexamethasone in hospitalized patients with Covid-19-preliminary report Tocilizumab treatment in COVID-19: a single center experience Antithrombotic treatments in patients with SARS-CoV-2 infection: from current evidence to reasonable recommendations-a position paper from the Italian Working Group on Atherosclerosis, Thrombosis and Vascular Biology Edoxaban for the treatment of cancer-associated venous thromboembolism Direct oral anticoagulant plasma levels' striking increase in severe COVID-19 respiratory syndrome patients treated with antiviral agents: the Cremona experience Hepatotoxicity of tocilizumab and anakinra in rheumatoid arthritis: management decisions COVID-19 and treatment with NSAIDs and corticosteroids: should we be limiting their use in the clinical setting? Pathophysiological basis and rationale for early outpatient treatment of SARS-CoV-2 (COVID-19) Infection Systematic review of the efficacy and safety of antiretroviral drugs against SARS, MERS or COVID-19: initial assessment Current overview on hypercoagulability in COVID-19 COVID-19 and thrombotic or thromboembolic disease: Finally, general practitioners were not able to immediately assist patients on VKAs in need of INR adjustments, as they were also fully involved in the management of COVID-19 patients.
    keywords: cov-2; covid-19; infection; patients; risk; ritonavir; sars; score; therapy; treatment; use; vte
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        item: #1968 of 7819
          id: cord-274545-r03g7w0b
      author: Ayele Mega, Teshale
       title: The Outcome of Hydroxychloroquine in Patients Treated for COVID-19: Systematic Review and Meta-Analysis
        date: 2020-10-13
       words: 6282
      flesch: 52
     summary: In the pooled analysis, the odds of adverse effects among COVID-19 patients treated with HCQ patients were increased by 2.35 (OR � 2.35; 95% CI: 1.15-4.8). However, clinical studies were reporting contradictory results on the efficacy and safety of HCQ when used for treating COVID-19 patients.
    keywords: covid-19; hcq; patients; prolongation; qtc; studies; study
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        item: #1969 of 7819
          id: cord-274554-vtg6l651
      author: Essadek, Aziz
       title: Mental health of French students during the Covid-19 pandemic
        date: 2020-08-25
       words: 849
      flesch: 46
     summary: Patient Health Questionnaire Psychometric properties of the general anxiety disorder 7-Item (GAD-7) scale in a heterogeneous psychiatric sample Validation de contenu de la version francophone du ques-tionnaire Impact of Event Scale-Revised selon les critères du DSM-5 Estimating the burden of SARS-Cov-2 in France Psychiatry disorders in students in six French universities: 12-Month prevalence, comorbidity, impairment and help-seeking A systematic review of studies of depression prevalence in university students The Mental Health Consequences of COVID-19 and Physical Distancing: The Need for Prevention and Early Intervention The first author (Aziz Essadek) conducted the study and analyzed the data. key: cord-274554-vtg6l651 authors: Essadek, Aziz; Rabeyron, Thomas title: Mental health of French students during the Covid-19 pandemic date: 2020-08-25 journal: J Affect Disord DOI: 10.1016/j.jad.2020.08.042 sha: doc_id: 274554 cord_uid: vtg6l651 This study evaluates the impact of Covid-19 on the mental health of 8004 French students in the East part of France, which has been the first and hardest hit region by the Covid-19 pandemic.
    keywords: students; study
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        item: #1970 of 7819
          id: cord-274558-1k7bi6ng
      author: Moiseev, Sergey
       title: Sex differences in mortality in the intensive care unit patients with severe COVID-19
        date: 2020-09-28
       words: 722
      flesch: 41
     summary: We investigated the sex-related differences in the occurrence of comorbidities and mortality rates in a nationwide study in 1522 consecutive patients with severe SARS-CoV-2 pneumonia who were admitted to intensive care unit (ICU) for respiratory support. The differences between mortality rates in males and females cannot be explained by comorbidities, given the divergent trends in the occurrence of chronic illnesses that may worsen survival in COVID-19 patients.
    keywords: covid-19; males; mortality
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        item: #1971 of 7819
          id: cord-274562-0mtwbwkk
      author: Olesen, Bente
       title: Infection prevention partners up with psychology in a Danish Hospital successfully addressing staffs fear during the COVID-19 pandemic
        date: 2020-04-24
       words: 610
      flesch: 42
     summary: Facilitation was combined with psychoeducation in coping strategies towards fear and high level of stress, and the education focused primarily on recalling staffs existing knowledge of infection prevention and secondly on how to use PPE correctly. Many were reassured of their professional ability to risk assess behavior when close to patients with COVID-19 and began trusting their knowledge of infection prevention and correct use of PPE.
    keywords: covid-19; infection
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        item: #1972 of 7819
          id: cord-274563-jimw6skv
      author: Fiumara, Agata
       title: COVID-19 Pandemic Outbreak and its Psychological Impact on Patients with Rare Lysosomal Diseases
        date: 2020-08-22
       words: 3526
      flesch: 45
     summary: Although no statistically significant difference was found compared to controls, we felt that the reactions were qualitatively different, underlining the fragility and isolation of such patients. key: cord-274563-jimw6skv authors: Fiumara, Agata; Lanzafame, Giuseppina; Arena, Alessia; Sapuppo, Annamaria; Raudino, Federica; Praticò, Andrea; Pavone, Piero; Barone, Rita title: COVID-19 Pandemic Outbreak and its Psychological Impact on Patients with Rare Lysosomal Diseases date: 2020-08-22 journal: J Clin Med DOI: 10.3390/jcm9092716 sha: doc_id: 274563 cord_uid: jimw6skv Background: Lysosomal storage disorders (LSDs) are rare, chronic, progressive multisystem diseases implying severe medical issues and psychological burden.
    keywords: control; covid-19; disease; group; home; patients
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        item: #1973 of 7819
          id: cord-274570-dcewfkmi
      author: Zhang, Xiao-Bo
       title: Response to children’s physical and mental needs during the COVID-19 outbreak
        date: 2020-05-25
       words: 1254
      flesch: 35
     summary: How can we cooperate with experts on public health and with educators on school health to perform health communication and to minimize the impact of the pandemic on children's physical and mental health? More than 200 doctors specialized in child health care from diversified specialties, including pediatric psychiatry, have been serving online in turn for 12 hours on a daily basis, from 8 am to 8 pm.
    keywords: approval; children; covid-19; health
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        item: #1974 of 7819
          id: cord-274581-mdk7vu36
      author: Grande, Giuseppe
       title: COVID-19 and the Gastrointestinal System: Lesions Beyond the Symptoms?
        date: 2020-09-24
       words: 1142
      flesch: 45
     summary: We present the patient presented with predominant respiratory symptoms correlated with COVID-19 infection, and the onset of acute dysphagia was unexpected and delayed. WHO Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures Effect of gastrointestinal symptoms on patients infected with COVID-19 Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection Infections of the esophagus: An update on risk factors, diagnosis, and management The digestive system is a potential route of COVID-19 infection: A bioinformatics analysis based on single-cell transcriptomes.
    keywords: coronavirus; covid-19; sars; symptoms
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        item: #1975 of 7819
          id: cord-274602-q9i2k304
      author: Iqbal, Yousaf
       title: Psychiatric presentation of patients with acute SARS-CoV-2 infection: a retrospective review of 50 consecutive patients seen by a consultation-liaison psychiatry team
        date: 2020-09-10
       words: 3719
      flesch: 40
     summary: Thirty-one patients were symptomatic (upper respiratory tract symptoms or pneumonia) for coronavirus disease 2019 (COVID-19) and 19 were asymptomatic (no characteristic physical symptoms of COVID-19 infection). As such it offers a broad clinical picture of the psychiatric problems associated with acute SARS-CoV-2 infection, occurring in a general hospital setting, and including patients who are symptomatic and asymptomatic for COVID-19 infection.
    keywords: consultation; cov-2; covid-19; infection; patients; sars; symptoms
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        item: #1976 of 7819
          id: cord-274628-xu18zf4l
      author: Ros, Maxime
       title: Increasing global awareness of timely COVID-19 healthcare guidelines through FPV training tutorials: Portable public health crises teaching method
        date: 2020-05-21
       words: 3022
      flesch: 42
     summary: This is also consistent with the social distance requirements to reduce unnecessary close proximity of a formal in-person educational classroom in order to educate and train students as well as J o u r n a l P r e -p r o o f communication sought to provide COVID-19 healthcare workers/responders a means to rapidly create educational content that can be deployed (i.e., at any time including just before any medical/surgical procedure) adequately, efficiently, and meaningfully to best alleviate the issues faced by hospitals, health-care workers/responders, and patients. The current COVID-19 pandemic has prompted a timely response from the healthcare system train a large and diverse group of healthcare workers/responders swiftly.
    keywords: covid-19; healthcare; learning; responders; workers
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        item: #1977 of 7819
          id: cord-274632-d9z0m2l8
      author: Chenna, Avantika
       title: Coronavirus Disease 2019 (COVID-19) in a Renal Transplant Patient
        date: 2020-05-09
       words: 1267
      flesch: 42
     summary: Transplant patients are particularly at a higher risk of contracting COVID-19 because of their immunosuppressed state, and they have the propensity to develop opportunistic infections. The pre-immunosuppressed state, along with other existing comorbidities, can influence the outcomes of COVID-19 in transplant patients.
    keywords: coronavirus; covid-19; patient; transplant
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        item: #1978 of 7819
          id: cord-274666-0d8oz51l
      author: Han, Yi
       title: Lactate dehydrogenase, an independent risk factor of severe COVID-19 patients: a retrospective and observational study
        date: 2020-06-24
       words: 3810
      flesch: 48
     summary: Severe patients had higher APACHE II (8.5 vs. 4.0) and SOFA (2 vs. 1) scores on admission. The median age was 63 years (IQR, 49-71 years), and severe patients were significantly older than the non-severe ones (67 vs. 61, P = 0.005).
    keywords: cells; covid-19; ldh; patients; severity; study
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        item: #1979 of 7819
          id: cord-274668-lh7c9izt
      author: Wang, Chaofu
       title: Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients
        date: 2020-06-20
       words: 4606
      flesch: 38
     summary: A graded decrease of T cells was found with increased clinical severity. Third, in this study, no ACE2-expression was found on the surface of T cells, which might be considered as an argument for the absence of direct toxic effect of SARS-CoV-2 on distinct T cell populations.
    keywords: alveolar; anti; cells; cov-2; covid-19; fig; human; lung; macrophages; patients; sars; tissues
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        item: #1980 of 7819
          id: cord-274677-7kcoodyv
      author: Dobson, Hanna
       title: Burnout and psychological distress amongst Australian healthcare workers during the COVID-19 pandemic
        date: 2020-10-12
       words: 1699
      flesch: 38
     summary: National Mental Health Survey of Doctors and Medical Students Depression in hospital-employed nurses Understanding the burnout experience Focus on mental health during the coronavirus (COVID-19) pandemic Burnout and Joy in the profession of critical care medicine Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019 Mental health outcomes among frontline and second-line health care workers during the coronavirus disease 2019 (COVID-19) pandemic in Italy Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic Validation and utility of a self-report version of PRIME-MD A brief measure for assessing generalized anxiety disorder Assessing psychological trauma and PTSD Psychometric analysis and refinement of the Connor-Davidson Resilience Scale (CD-RISC) key: cord-274677-7kcoodyv authors: Dobson, Hanna; Malpas, Charles B; Burrell, Aidan JC; Gurvich, Caroline; Chen, Leo; Kulkarni, Jayashri; Winton-Brown, Tobias title: Burnout and psychological distress amongst Australian healthcare workers during the COVID-19 pandemic date: 2020-10-12 journal: Australas Psychiatry DOI: 10.1177/1039856220965045 sha: doc_id: 274677 cord_uid: 7kcoodyv OBJECTIVE: To examine psychological distress in healthcare workers (HCWs) during the COVID-19 pandemic in April–May 2020.
    keywords: burnout; covid-19; distress; health; pandemic
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        item: #1981 of 7819
          id: cord-274694-kdsv7v8e
      author: Chathukulam, Jos
       title: The Kerala Model in the time of COVID19: rethinking State, Society and Democracy
        date: 2020-09-23
       words: 6373
      flesch: 47
     summary: Kerala's adversarial and competitive politics gave birth to public action which in turn laid the foundation for Kerala model of development. The logic behind approaching a foreign company when Kerala has institutions like Centre for Development of Imaging Technology (C-DIT) xiv and Kerala State IT Mission xv which are capable of handling big data analytics also raised doubts regarding governments decision.
    keywords: covid; development; government; india; kerala; kerala model; model; pandemic; people; public; social; society; state; world
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        item: #1982 of 7819
          id: cord-274702-x032pcwx
      author: Huang, Yu-Xi
       title: The database-based strategy may overstate the potential effects of traditional Chinese medicine against COVID-19
        date: 2020-06-23
       words: 843
      flesch: 40
     summary: key: cord-274702-x032pcwx authors: Huang, Yu-Xi; Wang, Wen-Xiao; Zhang, Sai; Tang, Yu-Ping; Yue, Shi-Jun title: The database-based strategy may overstate the potential effects of traditional Chinese medicine against COVID-19 date: 2020-06-23 journal: Pharmacol Res DOI: 10.1016/j.phrs.2020.105046 sha: doc_id: 274702 cord_uid: x032pcwx nan The database-based strategy may overstate the potential effects of traditional Chinese medicine against COVID-19 Yu -Xi
    keywords: chinese; covid-19; tcm
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        item: #1983 of 7819
          id: cord-274707-mxh38hwd
      author: Laureano, Ana Flávia Santarine
       title: The different tests for the diagnosis of COVID-19 - A review in Brazil so far
        date: 2020
       words: 3741
      flesch: 42
     summary: Most rapid tests use colloidal gold particles in a technique known as immunochromatography, also called lateral flow immunoassay, a type of sandwich assay that relies on a pair of antibodies used to recognize two independent epitopes of a protein, and therefore it can achieve high specificity (Zhou et al., 2012) . This kind of test is being used for pregnancy (Puertas et al., 2010) , HIV (Granade et al., 2010) , bacterial infections (Huang, 2007) , drugs of abuse (Gonzalez et al., 2011) , food contaminants and dengue virus (Cuzzubbo et al., 2001) , and many tests are commercially available (Zhou et al., 2012) .
    keywords: antibody; coronavirus; covid-19; dna; igm; pcr; sars; tests
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        item: #1984 of 7819
          id: cord-274710-ee780qe4
      author: Spencer, Robert
       title: COVID-19 and the young heart: what are we missing?
        date: 2020-09-09
       words: 1087
      flesch: 39
     summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children and adolescents: a systematic review Detection of viruses in myocardial tissues by polymerase chain reaction Diagnosis and treatment of myocarditis in children in the current era Survival without cardiac transplantation among children with dilated cardiomyopathy Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China Coronavirus disease 2019 (COVID-19) and cardiovascular disease Considerations for drug interactions on QTc in exploratory COVID-19 (Coronavirus Disease 2019) treatment. 274710 cord_uid: ee780qe4 nan COVID-19 develop some form of cardiac injury.
    keywords: cardiac; covid-19; patients
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        item: #1985 of 7819
          id: cord-274715-dcs1rgd0
      author: Mani Mishra, Pushpendra
       title: Serum albumin-mediated strategy for the effective targeting of SARS-CoV-2
        date: 2020-04-24
       words: 2151
      flesch: 34
     summary: Although some people infected with SARS CoV-2 have no symptoms, the spectrum of symptomatic infection ranges from mild to critical, with most COVID-19 infections being not severe. Although some people infected with SARS CoV-2 have no symptoms, the spectrum of symptomatic infection ranges from mild to critical, with most COVID-19 infections being not severe.
    keywords: albumin; covid-19; curcumin; infection; sars; strategy; virus
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        item: #1986 of 7819
          id: cord-274761-c2hgkbg6
      author: Rosenberg, Eli S.
       title: Cumulative incidence and diagnosis of SARS-CoV-2 infection in New York
        date: 2020-06-17
       words: 3437
      flesch: 40
     summary: Estimates of COVID-19 cumulative incidence (i.e. prevalence of previous or current infection) can inform the extent of epidemic spread as well as the number of persons still susceptible and progress towards herd immunity, which are critical for parameterizing simulation models and informing policies, including those for altering societal restrictions [5] . Following weighting, 12.5% were estimated reactive and following further adjustment for test characteristics, estimated cumulative incidence was 14 (Table 2 ).
    keywords: cov-2; covid-19; incidence; infection; non; nys; population; sars; testing
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        item: #1987 of 7819
          id: cord-274778-wds40e6i
      author: Tejedor, Santiago
       title: Information on the COVID-19 Pandemic in Daily Newspapers’ Front Pages: Case Study of Spain and Italy
        date: 2020-08-31
       words: 7823
      flesch: 48
     summary: The role of social media in spreading misleading health information is not new [3] , but the COVID-19 crisis has shown the critical impact of this new information environment [4] . In this sense, media practitioners and their organizations should be in charge of delivering rigorous health information, aimed at creating awareness about people's health, to prevent diseases and encourage healthy living.
    keywords: entities; figure; headlines; health; information; italy; media; news; page; pandemic; spain; total
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        item: #1988 of 7819
          id: cord-274802-7ioiwsd8
      author: Varghese, Praveen Mathews
       title: Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies
        date: 2020-08-19
       words: 19710
      flesch: 31
     summary: Unlike SARS, COVID-19 patients had the highest viral load near presentation, which could account for the fast-spreading nature of this epidemic. In a study involving COVID-19 patients in Hong Kong recorded high viral load on presentation with the onset of symptoms and also when the symptoms are mild (83) .
    keywords: activation; acute; antibodies; case; cells; china; complement; coronavirus; cov-2; covid-19; covid-19 patients; disease; dose; drug; high; human; infection; inflammation; injury; levels; novel; pathogenesis; patients; plasma; pneumonia; protein; response; sars; spike; studies; study; syndrome; system; transmission; treatment; trial; vaccine
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        item: #1989 of 7819
          id: cord-274816-6xpma224
      author: Onal, Merih
       title: Can secondary lymphoid organs exert a favorable effect on the mild course of COVID-19 in children?
        date: 2020-10-27
       words: 1426
      flesch: 36
     summary: A pneumonia outbreak associated with a new coronavirus of probable bat origin A COVID-19 Transmission within a family cluster by presymptomatic infectors in China Epidemiology of COVID-19 among children in China Seroepidemiological analysis of influenza pandemics in Shizuoka Prefecture and all Japan Short-and long-term impacts of adenoidectomy with/without tonsillectomy on immune function of young children <3 years of age: a cohort study Immunology of tonsils and adenoids: everything the ENT surgeon needs to know Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways Children with recurrent otitis show defective IFN-gamma producing cells in adenoids Current Scenario of COVID-19 in pediatric age group and physiology of immune and thymus response Diagnosis and treatment of 2019 novel coronavirus infection in children: a pressing issue Differential expression of immunoglobulin A in the adenoids of children with and without exudative otitis media Adenoid hypetrophy: definition of some risk factors Serum immunoglobulins in patients with chronic tonsillitis Early stage impacts of tonsillectomy on immune functions of children Tonsillar cytokine expression between patients with tonsillar hypertrophy and recurrent tonsillitis Intratonsillar detection of 27 distinct viruses: a cross-sectional study Profile of immunoglobulin production in adenoid and tonsil lymphocytes In fact, it is believed that when there is chronic inflammation in these organs, they do not play part in protection against upper respiratory tract infection and even inhibit immune response, enhancing the severity of the infection [17] .
    keywords: children; covid-19; ifn; study
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        item: #1990 of 7819
          id: cord-274824-kaefedl1
      author: Turski, Waldemar A.
       title: AhR and IDO1 in pathogenesis of Covid-19 and the “Systemic AhR Activation Syndrome:” a translational review and therapeutic perspectives
        date: 2020-09-24
       words: 5957
      flesch: 20
     summary: However, since CoV activates AhR, it may also lead to up-regulation of downstream effectors such as tissue factor (TF) and plasminogen activator inhibitor 1 (PAI-1) in endothelial cells, consistent with the role for AhR activation of AhR-TF/PAI-1 axis as a part of the host response to CoV infection (Belghasem et al., 2019) . IDO1 is a rate-limiting enzyme converting tryptophan to kynurenine, which is an endogenous ligand activating AhR. Inflammatory factors, such as tumor necrosis factor-␣ (TNF␣) and interleukins activate IDO1, whereas AhR also enhance their own activity through activation of a IDO1-AhR-IDO1 positive feedback loop prolonging the effects of AhR activation by other factors, including pathogens (Larigot, Jurice, Dairou, & Coumoul, 2018; Neavin, Liu, Ray, & Weinshilboum, 2018) .
    keywords: activation; ahr; ahrs; cov; cov-2; covid-19; et al; expression; ido1; infection; pathway; sars
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        item: #1991 of 7819
          id: cord-274834-24v2b509
      author: Lima, Rosiane
       title: Establishment of a pediatric COVID-19 biorepository: unique considerations and opportunities for studying the impact of the COVID-19 pandemic on children
        date: 2020-09-11
       words: 5596
      flesch: 36
     summary: The methodology described here, details the importance of establishing collaborations between the clinical and research teams to harmonize protocols for patient recruitment and sample collection, processing and storage. Cornerstones of the biorepository included open dialogue between research and clinical team members, a sensitivity to procedures required for specimen collection in children, and clear documentation of study participation and sample collection.
    keywords: biorepository; blood; children; clinical; collection; cov-2; covid-19; infection; patients; pediatric; research; samples; sars
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        item: #1992 of 7819
          id: cord-274841-rcdoewwv
      author: Tay, Matthew Zirui
       title: The trinity of COVID-19: immunity, inflammation and intervention
        date: 2020-04-28
       words: 7201
      flesch: 31
     summary: Prior immunization with severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) nucleocapsid protein causes severe pneumonia in mice infected with SARS-CoV A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge Developing Covid-19 vaccines at pandemic speed Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 Profiles of antibody responses against severe acute respiratory syndrome coronavirus recombinant proteins and their potential use as diagnostic markers Early detection of antibodies against various structural proteins of the SARS-associated coronavirus in SARS patients Neutralizing antibodies in patients with severe acute respiratory syndrome-associated Nature reviews | Immunology coronavirus infection Longitudinally profiling neutralizing antibody response to SARS coronavirus with pseudotypes Expert: recovered coronavirus patients are still prone to reinfection The Straits Times. The Straits Times Japanese man tests positive for coronavirus again China puts 245 COVID-19 patients on convalescent plasma therapy Use of convalescent plasma therapy in SARS patients in Hong Kong Retrospective comparison of convalescent plasma with continuing high-dose methylprednisolone treatment in SARS patients Experience of using convalescent plasma for severe acute respiratory syndrome among healthcare workers in a Taiwan hospital Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies A human monoclonal antibody blocking SARS-CoV-2 infection Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody Structure of SARS coronavirus spike receptor-binding domain complexed with receptor Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine The keypoints in treatment of the critical coronavirus disease 2019 patient Chinese doctors 'using plasma therapy' on COVID-19 patients 3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012 Press release details: Vir Biotechnology applying multiple platforms to address public health risk from Wuhan coronavirus Can an anti-HIV combination or other existing drugs outwit the new coronavirus Coronavirus treatment: vaccines/drugs in the pipeline for COVID-19 Neutralizing epitopes of the SARS-CoV S-protein cluster independent of repertoire, antigen structure or mAb technology Antibody responses to individual proteins of SARS coronavirus and their neutralization activities Receptor binding surveillance for high quality genomes Mutations in the spike protein of Middle East respiratory syndrome coronavirus transmitted in Korea increase resistance to antibodymediated neutralization Escape from human monoclonal antibody neutralization affects in vitro and in vivo fitness of severe acute respiratory syndrome coronavirus Evasion of antibody neutralization in emerging severe acute respiratory syndrome coronaviruses Neutralizing antibody response and SARS severity Is COVID-19 receiving ADE from other coronaviruses?
    keywords: acute; antibody; cells; coronavirus; cov; cov-2; covid-19; disease; infection; lung; patients; protein; responses; sars; severe; syndrome
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        item: #1993 of 7819
          id: cord-274849-awv8sp8m
      author: Iyengar, Karthikeyan P.
       title: COVID-19 and mortality in doctors
        date: 2020-09-03
       words: 2193
      flesch: 51
     summary: Frontline doctors that deal with COVID-19 patients seem to bear the brunt of mortality rates. Deaths were noted to be more common among general practitioners or physicians, suggesting a higher risk of deaths among doctors who may have repeated encounters with COVID-19 patients [15] .
    keywords: covid-19; doctors; health; india; mortality; ppe
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        item: #1994 of 7819
          id: cord-274860-7ec2jcoq
      author: Salazar, Eric
       title: Significantly decreased mortality in a large cohort of COVID-19 patients transfused early with convalescent plasma containing high titer anti-SARS-CoV-2 spike protein IgG
        date: 2020-11-04
       words: 4748
      flesch: 40
     summary: Retrospective analysis by the Ortho VITROS IgG assay revealed a median signal/cutoff (S/C) ratio of 24.0 for transfused units, a value far exceeding the recently FDA-required cutoff of 12.0 for designation of high titer convalescent plasma. With respect to altering mortality, our analysis identified an optimal window of 44 hours post-hospitalization for transfusing COVID-19 patients with high titer convalescent plasma.
    keywords: analysis; convalescent; covid-19; igg; mortality; patients; plasma; titer; transfusion
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        item: #1995 of 7819
          id: cord-274862-x580ktas
      author: Thomaier, L.
       title: Emotional health concerns of oncology physicians in the United States: fallout during the COVID-19 pandemic
        date: 2020-06-12
       words: 2362
      flesch: 46
     summary: key: cord-274862-x580ktas authors: Thomaier, L.; Teoh, D.; Jewett, P.; Beckwith, H.; Parsons, H.; Yuan, J.; Blaes, A. H.; Lou, E.; Hui, J. Y. C.; Vogel, R. I. title: Emotional health concerns of oncology physicians in the United States: fallout during the COVID-19 pandemic date: 2020-06-12 journal: medRxiv : the preprint server for health sciences DOI: 10.1101/2020.06.11.20128702 sha: doc_id: 274862 cord_uid: x580ktas Introduction: Cancer care is significantly impacted by the Coronavirus Disease 2019 (COVID-19) pandemic. Conclusion: The prevalence of anxiety and depression symptoms among oncology physicians in the United States during the COVID-19 pandemic is high.
    keywords: anxiety; covid-19; depression; preprint; symptoms
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        item: #1996 of 7819
          id: cord-274871-jlquvz51
      author: Nori, Priya
       title: Bacterial and fungal coinfections in COVID-19 patients hospitalized during the New York City pandemic surge
        date: 2020-07-24
       words: 2207
      flesch: 37
     summary: key: cord-274871-jlquvz51 authors: Nori, Priya; Cowman, Kelsie; Chen, Victor; Bartash, Rachel; Szymczak, Wendy; Madaline, Theresa; Punjabi Katiyar, Chitra; Jain, Ruchika; Aldrich, Margaret; Weston, Gregory; Gialanella, Philip; Corpuz, Marilou; Gendlina, Inessa; Guo, Yi title: Bacterial and fungal coinfections in COVID-19 patients hospitalized during the New York City pandemic surge date: 2020-07-24 journal: Infection control and hospital epidemiology DOI: 10.1017/ice.2020.368 sha: doc_id: 274871 cord_uid: jlquvz51 We observed bacterial or fungal coinfections in COVID-19 patients admitted between March 1 and April 18, 2020 (152 of 4,267, 3.6%).
    keywords: coinfections; covid-19; cultures; days; patients; study
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        item: #1997 of 7819
          id: cord-274918-dkl41b60
      author: Kwee, Thomas C.
       title: The “crisis after the crisis”: the time is now to prepare your radiology department
        date: 2020-04-22
       words: 1297
      flesch: 36
     summary: Radiology departments prepare for the surge of COVID-19 patients by employing policies and procedures to ensure sufficient capacity for continued operation, to support the care of COVID-19 patients, and to maintain radiologic services for the entirety of the hospital and health system [2] . After hospitals have overcome the peak load of COVID-19 patients and hospital capacities start to normalize, elective care processes will eventually be reinitiated.
    keywords: covid-19; crisis; department; radiology
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        item: #1998 of 7819
          id: cord-274934-s8xppipe
      author: Gebbia, Vittorio
       title: Patients With Cancer and COVID-19: A WhatsApp Messenger-Based Survey of Patients’ Queries, Needs, Fears, and Actions Taken
        date: 2020-05-15
       words: 3393
      flesch: 40
     summary: An R package for the extraction of sentiment and sentiment-based plot arcs from text Emotions evoked by common words and phrases: Using Mechanical Turk to create an emotion lexicon Managing cancer care during the COVID-19 pandemic: Agility and collaboration toward a common goal The blind leading the blind: COVID-19, cancer, and the need for more data COVID-19 and Cancer Consortium Patient engagement for metastatic breast cancer patients: WhatsApp counseling Assessing the feasibility and effectiveness of an app in improving knowledge on oral cancer-an interventional study WhatsApp in hospital? key: cord-274934-s8xppipe authors: Gebbia, Vittorio; Piazza, Dario; Valerio, Maria Rosaria; Borsellino, Nicolò; Firenze, Alberto title: Patients With Cancer and COVID-19:
    keywords: analysis; cancer; covid-19; data; oncologists; patients; queries; whatsapp
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        item: #1999 of 7819
          id: cord-274966-m2cw8hzb
      author: Ndiaye, Mor
       title: Procédure de dépistage d’une infection à COVID-19 en milieu de travail structuré africain
        date: 2020-05-21
       words: 1335
      flesch: 32
     summary: unité d'alerte chargée du recueil des informations ; -des équipes pour les prélèvements en vue des tests ; -des équipes de transport et acheminement des cas symptomatiques vers les centres de traitement et des cas asymptomatiques vers les sites de surveillance ; -des équipes pour le suivi psychologique ; -des équipes de santé au travail pour la protection des personnels engagés dans la riposte et le suivi professionnel. key: cord-274966-m2cw8hzb authors: Ndiaye, Mor; Diatta, Armandine Eusebia Roseline title: Procédure de dépistage d’une infection à COVID-19 en milieu de travail structuré africain date: 2020-05-21 journal: nan DOI: 10.1016/j.admp.2020.05.007 sha: doc_id: 274966 cord_uid: m2cw8hzb Résumé Alors qu’il n’existe de recommandation spécifique en Afrique Subsaharienne, le but de ce travail est de proposer aux professionnels de santé, un outil simple de détection des cas de COVID-19 parmi les travailleurs du secteur formel dans cette région.
    keywords: covid-19; des; les; travail
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        item: #2000 of 7819
          id: cord-275004-qzg03dvg
      author: Veras, Flavio Protasio
       title: SARS-CoV-2–triggered neutrophil extracellular traps mediate COVID-19 pathology
        date: 2020-09-14
       words: 6397
      flesch: 42
     summary: Production of NETs by isolated neutrophils Neutrophils (10 6 cells) obtained from COVID-19 patients or healthy controls were incubated with RPMI 1640 supplemented with 0.1% BSA treated or not with Cl-Amidine (200 µM; Sigma-Aldrich; cat. 506282), tenofovir disoproxil fumarate (TDF; 10 µM; as described in Clososki et al., 2020) , neutralizing anti-ACE2 antibody (αACE2; 0.5 µg/ml; Rhea Biotech; cat. IM-0060), camostat mesylate (Camostat; 10 µM; Sigma-Aldrich; cat. SML0057). The concentration of NETs was augmented in plasma, tracheal aspirate, and lung autopsies tissues from COVID-19 patients, and their neutrophils released higher levels of NETs.
    keywords: cells; controls; cov-2; covid-19; covid-19 patients; et al; fig; lung; nets; neutrophils; patients; release; sars
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        item: #2001 of 7819
          id: cord-275028-u6s0gr31
      author: Karos, Kai
       title: The social threats of COVID-19 for people with chronic pain
        date: 2020-07-13
       words: 4262
      flesch: 32
     summary: The role of revenge, denial, and terrorism distress in restoring just world beliefs: the impact of the 2008 Mumbai attacks on British and Indian students Individual differences in pain: understanding the mosaic that makes pain personal Behavioral methods in chronic pain and illness Well: what we need to talk about when we talk about health The communal coping model and cancer pain: the roles of catastrophizing and attachment style Correlates and consequences of chronic pain in older adults Chronic pain, social withdrawal, and depression Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science Loneliness and social isolation as risk factors for mortality: a meta-analytic review International Association for the Study of Pain Kiecolt-Glaser JK. Living with chronic pain can threaten an individuals' fundamental social needs for autonomy (agency or independence), belonging (social connection), and justice (fairness).
    keywords: access; care; covid-19; health; living; management; pain; pandemic; people; support
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        item: #2002 of 7819
          id: cord-275034-tq6tbhsn
      author: Hensel, D. J.
       title: Changes in Solo and Partnered Sexual Behaviors during the COVID-19 Pandemic: Findings from a U.S. Probability Survey
        date: 2020-06-11
       words: 5067
      flesch: 44
     summary: Understanding how and why changes occur is necessary to continue to adapt public health COVID-19 management in ways that are consistent with people's fundamental rights to sexual health and well-being. 27-32 Key resources like access to health care and services, access to condoms/contraception, and access to medications for sexual health, scaffold people's ability to control when they want to have sex, make sex more enjoyable, and reduce and/or avoid risk behaviors when sex occurs.
    keywords: behaviors; covid-19; health; june; license; medrxiv; month; perpetuity; preprint; sexual
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        item: #2003 of 7819
          id: cord-275038-zu6xmuql
      author: Bronte, V.
       title: Baricitinib restrains the immune dysregulation in COVID-19 patients
        date: 2020-06-29
       words: 5691
      flesch: 44
     summary: We then demonstrated that baricitinib treatment normalized the plasma concentration of several pro-inflammatory cytokines, which are produced in abnormal levels in COVID-19 as well as in CRS patients; indeed, 7 days after the first dose we detected a significant reduction in IL-1β, IL-6 and TNF plasma concentration within the baricitinib-treated patients but not in control group ( Figure 2C -E), supporting the standpoint of baricitinib as an effective therapeutic tool against the cytokine storm, a major cause of ARDS and multiple organ failure in COVID-19 patients (4). In a multiple logistic-regression model adjusted for age, sex and basal D-dimer at the baseline, an association between baricitinib treatment and low mortality was evident.
    keywords: baricitinib; cd8; cells; covid-19; days; figure; group; medrxiv; patients; preprint; treatment
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        item: #2004 of 7819
          id: cord-275041-fcdwitxy
      author: Ayerbe, Luis
       title: The association of treatment with hydroxychloroquine and hospital mortality in COVID-19 patients
        date: 2020-09-30
       words: 3260
      flesch: 46
     summary: Using limited evidence and clinical experience, doctors have treated COVID-19 patients with different drugs to eliminate or reduce the presence of the virus, including hydroxychloroquine (HCQ) Once it was approved for clinical use in COVID-19 patients, HCQ was started immediately after admission, and it was stopped if any abnormalities were identified in the ECGs that were done on a daily basis to patients who were taking it.
    keywords: covid-19; hcq; hydroxychloroquine; mortality; patients; study
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        item: #2005 of 7819
          id: cord-275068-yr076sl6
      author: Ayoub, Fares
       title: Football and COVID-19 risk: correlation is not causation
        date: 2020-09-03
       words: 447
      flesch: 34
     summary: [5] Low vitamin D levels have often been associated with a 16 higher risk of infections, but vitamin D supplementation has not been shown to prevent respiratory 17 1 impact journals during the pandemic, but it is important to remember that correlation does not equal 2 causation. A patients had a higher risk 9 of severe COVID-19 compared to other blood types,[3] while other studies have found associations 10 between vitamin D levels/latitude, and Bacille de Calmette et Guérin (BCG) vaccine and mortality to 11 COVID-19.
    keywords: covid-19; vitamin
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        item: #2006 of 7819
          id: cord-275071-2uiaruhg
      author: Balmford, Ben
       title: Cross-Country Comparisons of Covid-19: Policy, Politics and the Price of Life
        date: 2020-08-04
       words: 11187
      flesch: 52
     summary: The lowest estimates are further reduced once we correct for under-reporting of Covid-19 deaths. Accepting that they are a conservative estimate of the total impact of the pandemic, officially attributed Covid-19 deaths are used to investigate the price of life implied by lockdown policies.
    keywords: countries; country; covid-19; data; deaths; et al; gdp; life; lockdown; mortality; number; online; pandemic; policy; price
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        item: #2007 of 7819
          id: cord-275090-2gwv0vbs
      author: Odone, Anna
       title: The first 10,000 COVID-19 papers in perspective: Are we publishing what we should be publishing?
        date: 2020-08-20
       words: 858
      flesch: 50
     summary: More than 60% of published papers on COVID-19 are opinion pieces not reporting original data. Overall, the question remains: has the surge in scientific publication around COVID-19 been a positive, or a negative, for science?
    keywords: covid-19; papers; science
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        item: #2008 of 7819
          id: cord-275110-safr9z37
      author: Alexander, Paul Elias
       title: COVID-19 research has overall low methodological quality thus far: case in point for chloroquine/hydroxychloroquine
        date: 2020-04-21
       words: 3338
      flesch: 39
     summary: key: cord-275110-safr9z37 authors: Alexander, Paul Elias; Debono, Victoria Borg; Mammen, Manoj J.; Iorio, Alfonso; Aryal, Komal; Deng, Dianna; Brocard, Eva; Alhazzani, Waleed title: COVID-19 research has overall low methodological quality thus far: case in point for chloroquine/hydroxychloroquine date: 2020-04-21 journal: J Clin Epidemiol DOI: 10.1016/j.jclinepi.2020.04.016 sha: doc_id: 275110 cord_uid: safr9z37 What is new? The overall body of COVID-19 research is very flawed methodologically.
    keywords: covid-19; hydroxychloroquine; patients; research; studies; treatment
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        item: #2009 of 7819
          id: cord-275111-38hgg0jz
      author: Kumar, Abhishek
       title: Pattern of liver function and clinical profile in COVID-19: A cross-sectional study of 91 patients
        date: 2020-10-06
       words: 2304
      flesch: 55
     summary: A systematic review ST-Elevation Myocardial Infarction in Patients With COVID-19: Clinical and Angiographic Outcomes Neurological manifestations of COVID-19 and other coronavirus infections: A systematic review Review article: COVID-19 and liver disease-what we know on 1st key: cord-275111-38hgg0jz authors: Kumar, Abhishek; Kumar, Piyush; Dungdung, Ajit; Kumar Gupta, Anitesh; Anurag, Aditya; Kumar, Abhinav title: Pattern of liver function and clinical profile in COVID-19: A cross-sectional study of 91 patients date: 2020-10-06 journal: Diabetes Metab Syndr DOI: 10.1016/j.dsx.2020.10.001 sha: doc_id: 275111 cord_uid: 38hgg0jz BACKGROUND: – COVID-19 caused by SARS-CoV-2 leads to myriad range of organ involvement including liver dysfunction.
    keywords: cases; covid-19; levels; liver; patients; study
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        item: #2010 of 7819
          id: cord-275136-7atkrkhd
      author: Dolin, Raphael
       title: Remdesivir — An Important First Step
        date: 2020-05-27
       words: 997
      flesch: 42
     summary: Analysis of treatment effect according to stratification by clinical status (baseline ordinal value) showed an over-all benefit of treatment with remdesivir. After adjustments for baseline clinical status, the effects of 5 days and 10 days of remdesivir therapy were similar.
    keywords: days; remdesivir; treatment
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        item: #2011 of 7819
          id: cord-275142-40rf3ugf
      author: Slater, Sandy J.
       title: Recommendations for Keeping Parks and Green Space Accessible for Mental and Physical Health During COVID-19 and Other Pandemics
        date: 2020-07-09
       words: 2352
      flesch: 40
     summary: However, many public parks and green spaces were also closed because of concerns about social distancing, and most state and local shelter-in-place orders allow only limited use of parks and green space (6) . Streets with greenery, plants, or other natural features can be prioritized for these initiatives, given the positive association between public green space and mental health (28) (29) (30) .
    keywords: access; covid-19; health; parks; public; space
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        item: #2012 of 7819
          id: cord-275152-8if8shva
      author: Olum, R.
       title: Social Media Platforms for Health Communication and Research in the Face of COVID-19 Pandemic: A Cross Sectional Survey in Uganda.
        date: 2020-05-05
       words: 2485
      flesch: 51
     summary: date: 2020-05-05 journal: nan DOI: 10.1101/2020.04.30.20086553 sha: doc_id: 275152 cord_uid: 8if8shva Objectives: (1) To examine the usage of social media and other forms of media among medical students (MS) and healthcare professionals (HCPs) in Uganda. (2) To assess the perceived usefulness of social media and other forms of media for COVID-19 public health campaigns.
    keywords: covid-19; license; media; preprint; students
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        item: #2013 of 7819
          id: cord-275185-9br8lwma
      author: Zeng, Hao
       title: The efficacy assessment of convalescent plasma therapy for COVID-19 patients: a multi-center case series
        date: 2020-10-06
       words: 6621
      flesch: 46
     summary: Herein, we performed a retrospective observational study involving eight critical or severe patients with COVID-19 from four designated hospitals in the southwest region of China, aiming to explore the potential efficacy and safety of CP therapy, and to provide more evidence for the quality control of donated plasma and reasonable clinical application of CP transfusion. As the patients have been treated by antiviral drugs and oxygen support before CP therapy, the body temperature, heart rate, and systolic pressure were normal even prior to CP transfusion, and kept unchanged within 5 days after CP transfusion as indicated in Table 4 .
    keywords: convalescent; cov-2; covid-19; days; igg; patients; plasma; sars; specific; therapy; transfusion; treatment
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        item: #2014 of 7819
          id: cord-275191-lgze4zex
      author: Al-Sadeq, Duaa W.
       title: The incidence of the novel coronavirus SARS-CoV-2 among asymptomatic patients: a systematic review
        date: 2020-07-02
       words: 3294
      flesch: 40
     summary: medRxiv COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of New York City hospitals 18 F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases Comparative serological study for the prevalence of anti-MERS coronavirus antibodies in high-and low-risk groups in Qatar A serological assay to detect SARS-CoV-2 seroconversion in humans The relative transmissibility of asymptomatic COVID-19 infections among close contacts Almost 75% of people on board Diamond Princess with COVID-19 may have been asymptomatic Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship It worth mentioning that there is a high percent of COVID-19 asymptomatic patients who could transmit the infection to all communities.
    keywords: asymptomatic; coronavirus; cov-2; covid-19; infection; patients; sars; studies
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        item: #2015 of 7819
          id: cord-275202-zq4vvini
      author: Vu, David
       title: Three unsuspected CT diagnoses of COVID-19
        date: 2020-04-13
       words: 1709
      flesch: 51
     summary: Between these findings and our encounter with a patient with a basal ganglia hemorrhage, it will be important to pay closer attention to neurologic findings in COVID-19 patients in the future. Using imaging characteristics of COVID-19 on abdominal or neck CT when a portion of the lungs is included, patients not initially suspected of COVID-19 infection can be quarantined earlier to limit exposure to others.
    keywords: covid-19; findings; imaging; patient
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        item: #2016 of 7819
          id: cord-275214-mqvw0219
      author: Burlacu, Alexandru
       title: Is Thrombophilic Genetic Profile Responsible for an Acute Ischemic Stroke in a COVID-19 Male Patient?
        date: 2020-10-15
       words: 1022
      flesch: 31
     summary: COVID-19 associated coagulopathy and thrombotic complications Role of inherited thrombophilic profile on survival of patients with sepsis COVID19 coagulopathy in Caucasian patients ApoE e4e4 genotype and mortality with COVID-19 in UK Biobank ACE I/D but not AGT (-6)A/G polymorphism is a risk factor for mortality in ARDS Unpuzzling COVID-19 prothrombotic state: are preexisting thrombophilic risk profiles responsible for heterogenous thrombotic events? We strongly suspect that subtle genetic risk factors for thrombotic events may influence the COVID-19 course, might hold the key to understanding the significant heterogeneity of COVID-19 manifestations, and may prove useful in assessing the COVID-19 patients' risk for thrombosis and severe disease.
    keywords: covid-19; factor; risk; thrombosis
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        item: #2017 of 7819
          id: cord-275216-dnt88ycw
      author: Zhang, Xue-Yan
       title: Biological, clinical and epidemiological features of COVID-19, SARS and MERS and AutoDock simulation of ACE2
        date: 2020-07-20
       words: 4910
      flesch: 46
     summary: The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health -The latest 2019 novel coronavirus outbreak in Wuhan, China SARS and MERS: recent insights into emerging coronaviruses Preliminary prediction of the basic reproduction number of the Wuhan novel coronavirus 2019-nCoV The battle against SARS and MERS coronaviruses: Reservoirs and Animal Models The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts Applications of google search trends for risk communication in infectious disease management: a case study of COVID-19 outbreak in Taiwan Geographical tracking and mapping of coronavirus disease COVID-19/severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic and associated events around the world: how 21st century GIS technologies are supporting the global fight against outbreaks and epidemics Clinical trial analysis of 2019-nCoV therapy registered in China Retracted: clinical and epidemiological characteristics of 34 children with 2019 novel coronavirus infection in Shenzhen Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and gag Broad Spectrum antiviral agent Niclosamide and its therapeutic potential Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Patients of COVID-19 may benefit from sustained lopinavir-combined regimen and the increase of eosinophil may predict the outcome of COVID-19 progression Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2 COVID-19: gastrointestinal manifestations and potential fecal-oral transmission Review article: gastrointestinal features in COVID-19 and the possibility of faecal transmission Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes Acknowledgments AJE edited the manuscript for grammar, punctuation and spelling. Transmission route Viruses can directly infect people but can also infect one or more kinds of animals.
    keywords: coronavirus; cov-2; covid-19; epidemic; mers; novel; outbreak; patients; sars; transmission; treatment
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        item: #2018 of 7819
          id: cord-275228-952w7vx5
      author: Sharma, Yuvraj
       title: COVID-19–Associated Collapsing Focal Segmental Glomerulosclerosis: A Report of 2 Cases
        date: 2020-06-06
       words: 2111
      flesch: 27
     summary: We report 2 African American patients who developed acute kidney injury and proteinuria in temporal association with COVID-19 infection. 3, 4 We describe 2 African American patients with COVID-19 infection who presented with acute kidney injury and proteinuria.
    keywords: covid-19; glomerulopathy; injury; kidney; patients
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        item: #2019 of 7819
          id: cord-275238-5fledjac
      author: Gandolfini, Ilaria
       title: COVID‐19 in kidney transplant recipients
        date: 2020-04-12
       words: 484
      flesch: 39
     summary: At In kidney transplant recipients with COVID-19 who develop extensive pneumonia, which may require intubation, our current therapeutic approach includes stopping the immunosuppressive therapy (using steroids as the only antirejection drugs) to help promote the specific anti-viral immune response. In Northern Italy, where the current prevalence of confirmed cases has surpassed in some areas 2 per 1,000 people, kidney transplant patients are getting infected and starting to develop coronavirus disease 2019 (COVID-19).
    keywords: covid-19; transplant
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        item: #2020 of 7819
          id: cord-275243-knr3mat0
      author: Larsen, Kevin
       title: Detection of Pulmonary Embolism in Returning Travelers with Hypoxemic Pneumonia due to COVID-19 in Reunion Island
        date: 2020-07-01
       words: 1672
      flesch: 45
     summary: In the published literature, the incidence of thrombotic complications like pulmonary embolism or deep vein thrombosis in patients with COVID-19 pneumonia is highly variable, ranging from 1% to 20%. Moreover, it was not possible to perform a control group because the vast majority of COVID-19 patients came from Europe by long-haul flight (i.e., > 6,000 km).
    keywords: covid-19; embolism; patients; pneumonia; pulmonary
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        item: #2021 of 7819
          id: cord-275253-6pwqa8zk
      author: Shetty, Sameep S
       title: 10 “C” in COVID19
        date: 2020-05-29
       words: 912
      flesch: 35
     summary: Covid19 in high risk individuals display severe respiratory symptoms, multi organ involvement and may require a long term rehabilitation as in a chronic disease. The Lancet Infectious Diseases The oral surgery response to coronavirus disease (COVID-19) Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis
    keywords: contact; coronavirus; covid-19; covid19
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        item: #2022 of 7819
          id: cord-275257-upj8mvzn
      author: Hwang, E. Shelley
       title: Surgical Oncologists and the COVID-19 Pandemic: Guiding Cancer Patients Effectively through Turbulence and Change
        date: 2020-06-14
       words: 8502
      flesch: 36
     summary: key: cord-275257-upj8mvzn authors: Hwang, E. Shelley; Balch, Charles M.; Balch, Glen C.; Feldman, Sheldon M.; Golshan, Mehra; Grobmyer, Stephen R.; Libutti, Steven K.; Margenthaler, Julie A.; Sasidhar, Madhu; Turaga, Kiran K.; Wong, Sandra L.; McMasters, Kelly M.; Tanabe, Kenneth K. title: Surgical Oncologists and the COVID-19 Pandemic: Guiding Cancer Patients Effectively through Turbulence and Change date: 2020-06-14 journal: Ann Surg Oncol DOI: 10.1245/s10434-020-08673-6 sha: doc_id: 275257 cord_uid: upj8mvzn BACKGROUND: A summary of key measures that have established a framework from which to address these issues is provided, as well as additional strategies for managing resumption of surgical care in cancer patients.
    keywords: cancer; care; covid-19; covid-19 pandemic; guidelines; healthcare; hospitals; lung; pandemic; patients; risk; surgery; telemedicine; therapy; time; treatment; use; visits
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        item: #2023 of 7819
          id: cord-275260-xuhxqkyj
      author: Sardu, Celestino
       title: Hyperglycaemia on admission to hospital and COVID-19
        date: 2020-07-06
       words: 1204
      flesch: 39
     summary: To investigate the importance of glucose management of COVID-19 patients, we analysed recent data on glycaemic control and COVID-19 outcomes. This interpretation of the data underestimates the importance of glycaemic control in COVID-19 and may result in caregivers focusing attention on therapeutic management of hyperglycaemic patients.
    keywords: covid-19; disease; glucose; patients
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        item: #2024 of 7819
          id: cord-275261-t39kofet
      author: Ghosal, Samit
       title: Prediction of the number of deaths in India due to SARS-CoV-2 at 5–6 weeks
        date: 2020-04-02
       words: 1184
      flesch: 57
     summary: This analysis was aimed at tracing a trend related to death counts expected at the 5th and 6th week of the COVID-19 in India. This analysis was aimed at tracing a trend related to death counts 102 expected at the 5th and 6th week of the COVID-19 in India.
    keywords: data; death; week
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        item: #2025 of 7819
          id: cord-275264-bdtet83d
      author: Lee, Jong-Koo
       title: We Cannot Go Back to the Old World, Before Global Pandemic Declaration of the COVID-19 Pandemic: Developing New Normal Practices in Society
        date: 2020-08-17
       words: 664
      flesch: 48
     summary: Emerg Infect Dis COVID-19 therapeutic tracker DRAFT landscape of COVID-19 candidate vaccines WHO Director-General's opening remarks at the media briefing on COVID-19 -3 In many countries, essential services have been damaged due to paralysis of transportation facilities, closure of medical institutions, and a reduction in the number of individuals using these facilities due to COVID-19 lockdown.
    keywords: covid-19; korea; patients
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        item: #2026 of 7819
          id: cord-275266-e6omvo5x
      author: Kort, Nanne P
       title: Resuming hip and knee arthroplasty after COVID-19: ethical implications for well-being, safety and the economy
        date: 2020-07-07
       words: 5311
      flesch: 44
     summary: Following general social distancing principles, reallocation of treatment of elective patients into a private sector might reduce the risk of SARS-CoV-2 infection of elective patients, because public hospitals or academic centres are more often confronted with COVID-19 patients. Hence, a shift from elective joint arthroplasty patients from public hospitals into private hospitals would further disrupt clinical science and researchers and research questions might not be able to have direct contact with patients.
    keywords: arthroplasty; care; covid-19; elective; hip; hospitals; knee; pandemic; patients; risk; surgery; total
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        item: #2027 of 7819
          id: cord-275272-qdg8sqpy
      author: Soares-Júnior, José Maria
       title: Gynecology and women’s health care during the COVID-19 pandemic: Patient safety in surgery and prevention
        date: 2020-06-16
       words: 2039
      flesch: 34
     summary: In this context, based on a recent publication regarding patient safety in elective surgeries (9) (10) (11) , as well as on the law of access to treatment and laws related to women's health care (23, 24) , we propose the inclusion of gynecological surgery cases, stratified as follows ( Figure 1 ): Emergency (o1h): Peritonitis by tubo-ovarian and/or pelvic abscess, necrotizing fasciitis in surgeries for pelvic and breast neoplasms; DOI: 10.6061/clinics/2020/e2063 Urgent (o24h): Postoperative infections, acute inflammatory abdomen (adnexal tortoise, myoma tortoise, ovarian cysts), hemorrhagic conditions (ovarian cysts); Elective urgent (o2 weeks): Surgeries for neoplasms of the lower genital tract and breast previously diagnosed by pathological examination; Essential Elective (42 to o3 months): Hysteroscopy for abnormal uterine bleeding (unknowledge causes, suspected malignancy, and menopausal transition), postmenopausal bleeding (suspected malignancy), cervical conization or looped electro excision procedure (to exclude neoplasm in the lower genital tract); Non-essential/elective surgery: Infertility procedures, family planning procedures (bilateral tubal ligation procedure). Patients should be evaluated for possible viral infection, and universal screening should be considered for all surgical candidates and patients undergoing surgical procedures.
    keywords: care; covid-19; elective; health; pandemic; procedures; surgeries
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        item: #2028 of 7819
          id: cord-275274-ptgcd6tm
      author: Boon, Ian S.
       title: Digital healthcare and shifting equipoise in radiation oncology: The butterfly effect of the COVID-19 pandemic
        date: 2020-10-21
       words: 1451
      flesch: 30
     summary: key: cord-275274-ptgcd6tm authors: Boon, Ian S.; Lim, Jean S.; Au Yong, Tracy P.T.; Boon, Cheng S. title: Digital healthcare and shifting equipoise in radiation oncology: The butterfly effect of the COVID-19 pandemic date: 2020-10-21 journal: J Med Imaging Radiat Sci DOI: 10.1016/j.jmir.2020.10.002 sha: doc_id: 275274 cord_uid: ptgcd6tm nan The COVID-19 pandemic represents a significant disruptor in radiation oncology practice. 7, 8 Hypofractionation in radiation oncology has been shown to be iso-effective for major cancer sites.
    keywords: cancer; covid-19; oncology; pandemic; radiation
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        item: #2029 of 7819
          id: cord-275277-q0eghbna
      author: Zou, Huachun
       title: How Shenzhen, China avoided widespread community transmission: a potential model for successful prevention and control of COVID-19
        date: 2020-07-10
       words: 1945
      flesch: 39
     summary: In the wake of the 2003 SARS outbreak, Shenzhen health authority created a network for surveillance and responding to novel respiratory infections, including pneumonia of unknown causes (PUC). In the wake of the 2003 SARS outbreak, Shenzhen health authority created a network for detecting and responding to novel respiratory infections, including pneumonia of unknown cause (PUC).
    keywords: cases; city; community; control; covid-19; shenzhen
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        item: #2030 of 7819
          id: cord-275303-8mj8gjv9
      author: Chaudhuri, Swetaprovo
       title: Modeling the role of respiratory droplets in Covid-19 type pandemics
        date: 2020-06-01
       words: 8014
      flesch: 54
     summary: key: cord-275303-8mj8gjv9 authors: Chaudhuri, Swetaprovo; Basu, Saptarshi; Kabi, Prasenjit; Unni, Vishnu R.; Saha, Abhishek title: Modeling the role of respiratory droplets in Covid-19 type pandemics date: 2020-06-01 journal: Phys Fluids (1994) DOI: 10.1063/5.0015984 sha: doc_id: 275303 cord_uid: 8mj8gjv9 In this paper, we develop a first principles model that connects respiratory droplet physics with the evolution of a pandemic such as the ongoing Covid-19. The multi-scale model thus developed and the firm theoretical underpinning that connects the two scales—macro-scale pandemic dynamics and micro-scale droplet physics—thus could emerge as a powerful tool in elucidating the role of environmental factors on infection spread through respiratory droplets.
    keywords: ambient; cloud; droplet; evaporation; infection; lifetime; model; rate; salt; time; water
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        item: #2031 of 7819
          id: cord-275319-j36gnu0e
      author: Joob, B.
       title: COVID-19 in medical personnel: observation from Thailand
        date: 2020-04-30
       words: 446
      flesch: 48
     summary: This experience shows that respiratory infection control has to be considered for any patient with a possible infection, regardless of whether or not they have overt respiratory symptoms. COVID-19 can be easily missed in tropical countries, either because it occurs in conjunction with a common infectious disease (such as dengue), or because COVID-19 infection is misdiagnosed as another more common infection.
    keywords: covid-19; infection
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        item: #2032 of 7819
          id: cord-275334-0689o76n
      author: Amewu, Sena
       title: The Economic Costs of COVID-19 in Sub-Saharan Africa: Insights from a Simulation Exercise for Ghana
        date: 2020-10-30
       words: 7076
      flesch: 42
     summary: For this reason, government stimulus programs and social support packages should ideally complement social distancing and economic lockdown measures. Accra: Ghana Statistical Service (GSS) Rebased 2013-2019 annual gross domestic product Ghana COVID-19 monitoring dashboard Ghana Statistical Services (GSS), Institute of Statistical, Social and Economic Research (ISSER) and International Food Policy Research Institute (IFPRI)
    keywords: covid-19; demand; food; gdp; ghana; government; income; lockdown; losses; measures; model; sam; sector; supply
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        item: #2033 of 7819
          id: cord-275336-lnhkux0m
      author: Marino Gammazza, Antonella
       title: Human molecular chaperones share with SARS-CoV-2 antigenic epitopes potentially capable of eliciting autoimmunity against endothelial cells: possible role of molecular mimicry in COVID-19
        date: 2020-08-04
       words: 1939
      flesch: 28
     summary: We compared viral proteins with human molecular chaperones, many of which are heat shock proteins, to determine if they share amino acid-sequence segments with immunogenic-antigenic potential, which can elicit cross-reactive antibodies and effector immune cells with the capacity to damage-destroy human cells by a mechanism of autoimmunity. It has been demonstrated that stress agents induce HSP90 localization on the surface of primary human endothelial cells (Profumo et al. 2018) , and HSP60 is present on the surface of arterial endothelial cells, initiating atherosclerosis by the recognition of atherogenic HSP60 epitopes (Almanzar et al. 2012) .
    keywords: cell; chaperones; covid-19; human
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        item: #2034 of 7819
          id: cord-275340-q8d7rvnj
      author: Sun, JingKang
       title: Advances in the use of chloroquine and hydroxychloroquine for the treatment of COVID-19
        date: 2020-06-21
       words: 6638
      flesch: 44
     summary: In a randomized clinical trial from Wuhan about HCQ treatment of mild COVID-19 [50] , 31 out of 62 patients received HCQ (200 mg/2 times/day for 5 days). In the initial trial from France, of the 84 patients receiving HCQ treatment, 8 patients discontinued HCQ owing to ECG modifications within 4 days.
    keywords: activity; azithromycin; coronavirus; cov-2; covid-19; group; hcq; patients; results; sars; studies; study; treatment
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        item: #2035 of 7819
          id: cord-275349-b35pt3mo
      author: Lenz, Heinz-Josef
       title: The Emergence of Baricitinib: A Story of Tortoises Versus Hares
        date: 2020-07-06
       words: 1406
      flesch: 29
     summary: Baricitinib treatment over prolonged periods in RA patients has been associated with increased infections and thromboembolism, but the short duration of treatment in COVID-19 patients may mitigate against such side effects. One would be advised to remain vigilant of such signals reflecting thromboembolic or infection risk in randomized controlled trials testing a variety of immunomodulatory therapies in COVID-19 patients, either alone or in combination, especially in view of associations between clots and SARS-CoV-2 infection [10] .
    keywords: baricitinib; covid-19; patients; treatment
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        item: #2036 of 7819
          id: cord-275350-m1rv2i11
      author: Maserat, Elham
       title: COVID-19 & an NGO and university developed interactive portal: a perspective from Iran
        date: 2020-08-17
       words: 2901
      flesch: 38
     summary: World Health Organization Managing COVID-19 in lowand middle-income countries Balancing health privacy, health information exchange, and research in the context of the COVID-19 pandemic Association of public health interventions with the epidemiology of the COVID-19 outbreak in Wuhan, China An investigation of specifications for migrating to a web portal framework for the dissemination of health information within a public health network COVID-19: what is next for public health? Global chemotherapy demands: a prelude to equal access Improving service quality, accountability and transparency of local government: the intervening role of information technology governance Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations 1 Architecture of the webportal web-based portal facilitates dissemination of public health information [27] , as is the case in the current study.
    keywords: covid-19; health; information; ngos; portal; public; web
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        item: #2037 of 7819
          id: cord-275353-ezrmuw48
      author: Donma, Mustafa Metin
       title: The Effects of Allium Sativum on Immunity within the Scope of COVID-19 Infection
        date: 2020-06-02
       words: 2512
      flesch: 38
     summary: In conclusion, Allium sativum may be an acceptable preventive measure against COVID-19 infection to boost immune system cells and to repress the production and secretion of proinflammatory cytokines as well as an adipose tissue derived hormone leptin having the proinflammatory nature. Decreased immune system cells such as suppressed regulatory T cells, cytotoxic and helper T cells, natural killer cells, monocytes/macrophages and increased proinflammatory cytokines are the characteristic features.
    keywords: cells; covid-19; garlic; immune; infection; leptin
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        item: #2038 of 7819
          id: cord-275370-bt45gnqk
      author: Arellano-Cotrina, Josabet Johana
       title: Effectiveness and Recommendations for the Use of Dental Masks in the Prevention of COVID-19: A Literature Review
        date: 2020-07-17
       words: 3795
      flesch: 43
     summary: 24 Regarding mask sterilization, although it is necessary to determine the exact UVGI doses for mask sterilization against the SARS-CoV-2 virus, this strategy provides a possibility to extend the use of the limited supply of respirator masks against COVID-19, being both profitable and accessible. A major problem with respirator masks is discomfort and the generation of humidity inside, decreasing air permeability.
    keywords: capacity; coronavirus; covid-19; health; masks; n95; respirators; sterilization; use
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        item: #2039 of 7819
          id: cord-275381-343y0bsh
      author: Guella, Adnane
       title: Favorable Outcome of COVID-19 Pneumonia in a Kidney Transplant Recipient Treated with Tocilizumab
        date: 2020-09-16
       words: 1669
      flesch: 50
     summary: e management of COVID-19 pneumonia in kidney transplant patients is a challenging situation as no optimal strategy is currently known. key: cord-275381-343y0bsh authors: Guella, Adnane; Elfadil, Osman; Abdulrazaq, Ghisson; Osman, Sahla; Khan, Mohammed Munir; Ahmed, Abdalla; Deyab, Feras title: Favorable Outcome of COVID-19 Pneumonia in a Kidney Transplant Recipient Treated with Tocilizumab date: 2020-09-16 journal: Case Rep Infect Dis DOI: 10.1155/2020/8830626 sha: doc_id: 275381 cord_uid: 343y0bsh The presentation of COVID-19 pneumonia in kidney transplant recipients is similar to that of the general population.
    keywords: covid-19; kidney; pneumonia; transplant
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        item: #2040 of 7819
          id: cord-275391-dmfacaua
      author: Liu, Yuan
       title: Anxiety and depression symptoms of medical staff under COVID-19 epidemic in China
        date: 2020-09-07
       words: 2757
      flesch: 47
     summary: key: cord-275391-dmfacaua authors: Liu, Yuan; Chen, Hongguang; Zhang, Nan; Wang, Xing; Fan, Qinyi; Zhang, Yuling; Huang, Liping; Hu, Bo; Li, Mengqian title: Anxiety and depression symptoms of medical staff under COVID-19 epidemic in China date: 2020-09-07 journal: J Affect Disord DOI: 10.1016/j.jad.2020.09.004 sha: doc_id: 275391 cord_uid: dmfacaua BACKGROUND: : It is well known that unexpected pandemic has led to an increase in mental health problems among a variety of populations. Under outbreak of COVID-19, self-reported rates of anxiety symptoms and depression symptoms were high in investigated medical staff.
    keywords: anxiety; depression; self; staff; symptoms
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        item: #2041 of 7819
          id: cord-275395-w2u7fq1g
      author: Romero-Severson, Ethan Obie
       title: Change in global transmission rates of COVID-19 through May 6 2020
        date: 2020-08-06
       words: 4024
      flesch: 52
     summary: Most countries showed large decreases in transmission rates over time, and more than half of studied countries have transmission rates below the epidemic threshold. The model is then simulated forward for 21 days, assuming exponential growth with transmission rate χ 0 , which is taken at the initial state of the model at time zero.
    keywords: countries; data; deaths; model; rate; time; transmission
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        item: #2042 of 7819
          id: cord-275438-drywzvx8
      author: Satış, Hasan
       title: Prognostic value of interleukin-18 and its association with other inflammatory markers and disease severity in COVID-19
        date: 2020-09-29
       words: 3544
      flesch: 42
     summary: However, exuberant immune response with features of macrophage activation syndrome (MAS) lead detrimental consequences in COVID-19 patients. Serum IL-18 levels were remarkably higher in COVID-19 patients compared to healthy subjects with being highest in severe pneumonia group (p < 0.001).
    keywords: covid-19; cytokine; disease; il-18; il-6; outcome; patients; sars; serum
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        item: #2043 of 7819
          id: cord-275447-nx45kwn6
      author: Ehrenpreis, Eli D.
       title: Rapid Review: Nonsteroidal Anti-inflammatory Agents and Aminosalicylates in COVID-19 Infections
        date: 2020-06-10
       words: 2353
      flesch: 41
     summary: key: cord-275447-nx45kwn6 authors: Ehrenpreis, Eli D.; Kruchko, David H. title: Rapid Review: Nonsteroidal Anti-inflammatory Agents and Aminosalicylates in COVID-19 Infections date: 2020-06-10 journal: J Clin Gastroenterol DOI: 10.1097/mcg.0000000000001371 sha: doc_id: 275447 cord_uid: nx45kwn6 In the current COVID-19 pandemic, there has been concern regarding the use of ibuprofen and other nonsteroidal anti-inflammatory agents by COVID-19 infected patients. On March 14, the French Health Minister Olivier Véran, tweeted that taking anti-inflammatory drugs [ibuprofen (or) cortisone] could be an aggravating factor for the infection.
    keywords: asas; covid-19; ibuprofen; nsaids; patients; use
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        item: #2044 of 7819
          id: cord-275452-ymimvoq9
      author: Ameen, Fuad
       title: Covid-19 pandemic outburst in Saudi Arabia: A Glimpse
        date: 2020-07-30
       words: 2465
      flesch: 42
     summary: Extensive and continuous studies going on covid-19 infections have specified initial and later disease syndromes (Fig. 2) . In broader sense the warning signs of covid-19 infection normally emerge out following an incubation time of roughly two to fourteen days ).
    keywords: cases; coronavirus; covid-19; novel; sars; saudi
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        item: #2045 of 7819
          id: cord-275477-blu6wjhu
      author: Trimaille, Antonin
       title: COVID-19 et pathologie thromboembolique veineuse
        date: 2020-09-29
       words: 2416
      flesch: 26
     summary: Patients: Awareness of an Increased Prevalence Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Incidence of venous thromboembolism in hospitalized patients with COVID-19 Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Extremely High Incidence of Lower Extremity Deep Venous Thrombosis in 48 Patients With Severe COVID-19 in Wuhan Acute Pulmonary Embolism Associated with COVID-19 Pneumonia Detected by Pulmonary CT Angiography Pulmonary embolism in COVID-19 patients: a French multicentre cohort study High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Venous thromboembolism in critically Ill patients with COVID-19: Results of a screening study for deep vein thrombosis Incidence of asymptomatic deep vein thrombosis in patients with COVID-19 pneumonia and elevated D-dimer levels Venous thromboembolism in non-critically ill patients with COVID-19 infection Deep Vein Thrombosis in Hospitalized Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: Prevalence, Risk Factors, and Outcome Systematic assessment of venous thromboembolism in COVID-19 patients receiving thromboprophylaxis: incidence and role of D-dimer as predictive factors High prevalence of deep vein thrombosis in mechanically ventilated COVID-19 patients Incidence of deep vein thrombosis among non-ICU patients hospitalized for COVID-19 despite pharmacological thromboprophylaxis Venous Thrombosis Among Critically Ill Patients With Coronavirus Disease 2019 (COVID-19) ETEV au cours de la COVID-19 aggrave le pronostic des patients (3, 4) .
    keywords: cours; covid-19; dans; des; etev; incidence; les; patients; une
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        item: #2046 of 7819
          id: cord-275506-3t5gf66c
      author: Agbuduwe, Charles
       title: Hematolological Manifestations of COVID‐19: From Cytopenia to Coagulopathy
        date: 2020-07-14
       words: 4288
      flesch: 27
     summary: [17] In addition to a significant reduction in both CD4+ and CD8+ T lymphocyte subsets in COVID-19 patients, severe cases had much lower CD8+ lymphocytes and a subsequent increase positively correlated with improved clinical outcomes. [14] Similar findings were reported in a French cohort study with mild thrombocytopenia identified in about a quarter of COVID-19 patients on admission to hospital and this was independently predictive of the risk of admission to ICU, mechanical ventilation or death.
    keywords: article; blood; cases; cov-2; covid-19; disease; patients; sars; study
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        item: #2047 of 7819
          id: cord-275510-fotolimq
      author: Sytwu, Huey-Kang
       title: Expeditious responses to COVID-19 crisis: from governmental management to laboratory approach
        date: 2020-09-19
       words: 1459
      flesch: 32
     summary: f CECC requested National Health Research Institutes (NHRI), the only mission-oriented medical and health research center in Taiwan, to take the responsibility in coordinating clinical resources and provide a national technology platform for COVID-19 research. Taiwan is so close to Mainland China and was expected to have a very high incidence and number of COVID-19 cases in 2020.
    keywords: covid-19; health; outbreak; taiwan
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        item: #2048 of 7819
          id: cord-275531-88iqxzqc
      author: Yu, Xinyu
       title: Management of acute aortic dissection during the COVID-19 pandemic: Experience from an epicenter in Wuhan, China
        date: 2020-05-10
       words: 569
      flesch: 45
     summary: Hence, patients with acute aortic dissection could potentially be carriers of SARS-Cov-2 (the pathogen of COVID-19) and might cause a spread of nosocomial infections in hospitals. Efficient emergency networks were well preserved, ensuring a timely diagnosis and treatment for patients with acute aortic dissection.
    keywords: covid-19; patients
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        item: #2049 of 7819
          id: cord-275556-798oed8n
      author: Piubelli, Chiara
       title: Overall decrease of SARS-CoV-2 viral load and reduction of clinical burden: the experience of a Northern Italy hospital
        date: 2020-10-12
       words: 611
      flesch: 45
     summary: In this work, we aimed at evaluating a possible association between the severity of clinical manifestations and viral load over time, during the epidemiological transition from high to low transmission setting. As for viral load, we observed a trend of Ct increasing from a median value of 24 (IQR 19-29) to 34 (IQR 29-37) between March and May, with a statistically significant difference between March and April (Pairwise Wilcoxon test with Stepdown Bonferroni Adjustment for multiple testing, p=0.0003).
    keywords: covid-19; load
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        item: #2050 of 7819
          id: cord-275557-peo4d1hn
      author: Musa, Arif
       title: Addendum to Systematic Review of Remdesivir for the Treatment of COVID-19
        date: 2020-05-22
       words: 897
      flesch: 44
     summary: On April 10, Grein et al reported that most patients given remdesivir in an open-label program exhibited observable clinical improvement. A Systematic Review of the Literature Compassionate use of remdesivir for patients with severe Covid-19 Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multi-centre trial NIH clinical trial shows remdesivir accelerates recovery from advanced COVID-19 Adaptive COVID-19 Treatment Trial (ACTT) Remdesivir EUA Letter of Authorization -FDA
    keywords: covid-19; remdesivir; treatment
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        item: #2051 of 7819
          id: cord-275584-zeqax0il
      author: Mahil, S. K.
       title: Risk mitigating behaviours in people with inflammatory joint and skin disease during the COVID-19 pandemic differ by treatment type: a cross-sectional patient survey
        date: 2020-11-07
       words: 4057
      flesch: 40
     summary: The reasons underlying differences in shielding behaviours between treatment groups, including patient perceptions of COVID-19 risk, also warrant further study. Ascertainment bias may overestimate the overall proportion shielding, since those more concerned about COVID-19 risk may be more likely to participate.
    keywords: behaviour; covid-19; data; license; preprint; risk; shielding; treatment
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        item: #2052 of 7819
          id: cord-275595-q1hyxevb
      author: Ruan, Xiaofeng
       title: Mechanism of Dayuanyin in the treatment of coronavirus disease 2019 based on network pharmacology and molecular docking
        date: 2020-06-12
       words: 4847
      flesch: 45
     summary: The above DYY drug target genes were intersected with COVID-19 disease targets to obtain possible genes associated with DYY treatment of COVID-19. Drug target genes and disease related genes were intersected, and a total of 45 target genes for DYY treatment of COVID-19 were finally obtained (Additional file 2: Fig. S2 ).
    keywords: compounds; core; covid-19; database; disease; dyy; fig; genes; network; pathway; target; treatment
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        item: #2053 of 7819
          id: cord-275601-9y5zj9an
      author: Boutron, Isabelle
       title: The COVID-NMA Project: Building an Evidence Ecosystem for the COVID-19 Pandemic
        date: 2020-09-15
       words: 1367
      flesch: 45
     summary: In addition, although evidence synthesis is directly affected by the quality of primary research, interaction is limited between the evidence generation and synthesis communities. Introduction evidence synthesis ecosystem needs dramatic change Meta-analysis and the science of research synthesis China Medical Treatment Expert Group for Covid-19.
    keywords: covid-19; data; evidence; research; trials
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        item: #2054 of 7819
          id: cord-275637-ea6w2kqv
      author: Roca-Fernandez, A.
       title: HIGH LIVER FAT ASSOCIATES WITH HIGHER RISK OF DEVELOPING SYMPTOMATIC COVID-19 INFECTION - INITIAL UK BIOBANK OBSERVATIONS
        date: 2020-06-05
       words: 2915
      flesch: 40
     summary: Liver fat >5% is diagnostic of fatty liver disease (19) ; liver fat >10% is considered to qualify as severe fatty liver disease and is a commonly used inclusion criteria in clinical trials of patients with non-alcoholic steatohepatitis (NASH) (20) . . Multiparametric MRI measuring liver fat and fibroinflammation has demonstrated value in characterising liver disease (12, 13) and predicting clinical outcomes (14) .
    keywords: covid-19; disease; license; liver; medrxiv; preprint
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        item: #2055 of 7819
          id: cord-275660-zdw50gt2
      author: Mao, Kang
       title: The potential of an integrated biosensor system with mobile health and wastewater-based epidemiology (iBMW) for the prevention, surveillance, monitoring and intervention of the COVID-19 pandemic
        date: 2020-09-16
       words: 1737
      flesch: 34
     summary: The real-time data 257 collected and transmitted by the iBMW not only provide timely health care and treatment for patients 258 but also allow for the timely implementation of epidemic control measures. In this communication, we discuss the feasibility of an integrated point-of-care biosensor system with mobile health for wastewater-based epidemiology (iBMW) for early warning of COVID-19, screening and diagnosis of potential infectors, and improving health care and public health.
    keywords: covid-19; diagnosis; health; potential
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        item: #2056 of 7819
          id: cord-275675-gzd75ks9
      author: Gee, Siobhan
       title: The effect of COVID-19 on absolute neutrophil counts in patients taking clozapine
        date: 2020-07-16
       words: 1522
      flesch: 50
     summary: Patients taking clozapine who develop neutroapaenia during COVID-19 infection should be investigated and monitored as in normal practice, because changes in neutrophil counts cannot be assumed to be due to the viral infection. Patients taking clozapine who develop neutroapaenia during COVID-19 infection should be investigated and monitored as in normal practice, because changes in neutrophil counts cannot be assumed to be due to the viral infection.
    keywords: clozapine; covid-19; patients
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        item: #2057 of 7819
          id: cord-275693-ej76fsxa
      author: Stanislau Affonso de Araujo, E.
       title: Teach, and teach and teach: does the average citizen use masks correctly during daily activities? Results from an observational study with more than 12,000 participants
        date: 2020-06-28
       words: 1988
      flesch: 60
     summary: Among the core measures to prevent disease spread is the use of face masks. Even though this is densely populated region and heavily impacted by COVID-19 with a high risk population, only 45.1% of the observed population wore in face masks in a correct way, and another 15.5% simply did not use masks at all.
    keywords: license; masks; medrxiv; preprint
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        item: #2058 of 7819
          id: cord-275696-xag08e8h
      author: Dharamsi, A.
       title: Enhancing departmental preparedness for COVID-19 using rapid cycle in situ simulation
        date: 2020-06-13
       words: 2334
      flesch: 47
     summary: These themes were organized by simulation session date to identify persistence and/or resolution of safety threats. Safety threats in the PPE domain generally required only a single session to resolve after identification.
    keywords: care; covid-19; iss; safety; simulation; team; threats
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        item: #2059 of 7819
          id: cord-275711-ejw3ausf
      author: Mon-López, Daniel
       title: The Impact of Covid-19 and the Effect of Psychological Factors on Training Conditions of Handball Players
        date: 2020-09-05
       words: 5822
      flesch: 41
     summary: Regarding the competition level, there was a greater training time reduction in professional handball players (Tdays, p = 0.004; Thours, p < 0.001) than in non-professionals (Tdays, p > 0.05; Thours, p > 0.05). Relevant training reductions in volume and intensity were detected, especially in women and professionals, while a decrease in sleep quality was identified in professional handball players, especially in men.
    keywords: conditions; covid-19; handball; isolation; non; period; players; sleep; step; training
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        item: #2060 of 7819
          id: cord-275721-l6l7bln0
      author: Hussain, Azhar
       title: The Pan London Emergency Cardiac Surgery service: Coordinating a response to the COVID‐19 pandemic
        date: 2020-06-29
       words: 2204
      flesch: 44
     summary: Cardiac surgical patients can be considered in a few categories depending on clinical urgency. Inevitably, frontline staff treating cardiac surgical patients may at some point expect to have to self-isolate either as a result of themselves becoming symptomatic or inhabiting with someone who is symptomatic.
    keywords: center; delivery; patients; plecs; surgery
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        item: #2061 of 7819
          id: cord-275737-jg45bnzq
      author: Mughal, Z
       title: Test, test, test – a complication of testing for coronavirus disease 2019 with nasal swabs
        date: 2020-07-09
       words: 2020
      flesch: 44
     summary: This paper draws attention to a complication of viral swab testing in the nasopharynx and describes the premature engagement of a viral swab breakpoint, resulting in impaction in the nasal cavity. As the incidence of new cases of coronavirus disease 2019 increases exponentially, the use of viral swabs to collect nasopharyngeal specimens is anticipated to increase drastically.
    keywords: cavity; coronavirus; covid-19; nasal; patient; swab
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        item: #2062 of 7819
          id: cord-275754-1thebz19
      author: García Bascones, M.
       title: Luchando contra la covid-19: labor asistencial de los médicos rehabilitadores españoles. Estudio transversal
        date: 2020-08-08
       words: 2883
      flesch: 31
     summary: Métodos: Se realiza una encuesta dirigida a los tutores de los Servicios de Rehabilitación. -Adaptación de los Servicios de Rehabilitación a la crisis.
    keywords: como; con; covid; covid-19; del; durante; han; las; los; médicos; pacientes; pandemia; para; que; rehabilitación; rehabilitadores; servicios
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        item: #2063 of 7819
          id: cord-275784-n6jv72l7
      author: Spina, Alfio
       title: The Management Of Neurosurgical Patients During The Covid-19 Pandemic
        date: 2020-04-30
       words: 2231
      flesch: 39
     summary: It is well known that COVID-19 patients harbor a higher risk of thrombosis and secondary pulmonary infections, hence adequate treatment has to be warranted. Case selection, operating room and postoperative management of neurosurgical patients were discussed.
    keywords: coronavirus; covid-19; healthcare; pandemic; patients; surgery
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        item: #2064 of 7819
          id: cord-275833-c3zamfix
      author: McElligott, Helen
       title: Hybrid-CERAB (Covered Endovascular Reconstruction of the Aortic Bifurcation) Procedure is preferable to Aorto-Bi-Femoral Bypass for Limb-threatening Aortoiliac Occlusive Disease during the COVID-19 Crisis.
        date: 2020-09-02
       words: 1165
      flesch: 41
     summary: This case reports the management of a patient with complex aorto-iliac occlusive disease via a hybrid endovascular approach in light of the above constraints, with a successful outcome. Concerns regarding post-operative mortality in the event of SARS-Cov2 infection, 7 critical care bed capacity and inpatient length of stay will undoubtedly lead to a re-imagining of 8 the role of endovascular therapy in the management of complex aorto-iliac occlusive disease.
    keywords: care; disease; endovascular; surgery
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        item: #2065 of 7819
          id: cord-275842-dtdb4yuc
      author: Nachmias, Vered
       title: The First Case of Documented Covid-19 Reinfection in Israel
        date: 2020-10-01
       words: 1165
      flesch: 53
     summary: The Verge Two cases of Covid -19 reinfection reported in Europe CGTN: Ecuador confirms first case of COVID-19 reinfection Israel ranks third in highest daily infection rate among European countries, WHO says Immune responses to viruses key: cord-275842-dtdb4yuc authors: Nachmias, Vered; Fusman, Renato; Mann, Susie; Koren, Gideon title: The First Case of Documented Covid-19 Reinfection in Israel date: 2020-10-01 journal: IDCases DOI: 10.1016/j.idcr.2020.e00970 sha: doc_id: 275842 cord_uid: dtdb4yuc We describe the first documented case of Covid-19 reinfection in Israel, out of only a handful such case worldwide, in a 20 year old otherwise healthy young woman.
    keywords: case; covid-19
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        item: #2066 of 7819
          id: cord-275852-hvbsx5an
      author: Lachapelle, F.
       title: COVID-19 Preprints and Their Publishing Rate: An Improved Method
        date: 2020-09-07
       words: 9307
      flesch: 50
     summary: Given the strong integration movement described earlier and research indicating the positive relationship between time elapse since first upload and formal publication it is likely that a reproduction of Gianola et al.'s or Fraser et al.' study will find an increased proportion of published COVID-19 preprints. COVID-19 preprints uploaded up to April 31 st , 2020 report a publishing rate of 4% (n=101) (Fraser et al., 2020) .
    keywords: author; copyright; covid-19; funder; holder; license; medrxiv; peer; perpetuity; preprint; review; version
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        item: #2067 of 7819
          id: cord-275853-fym8qze2
      author: Yang, Juan
       title: Disease burden and clinical severity of the first pandemic wave of COVID-19 in Wuhan, China
        date: 2020-09-01
       words: 6459
      flesch: 44
     summary: The probability of seeking medical treatment conditionally on 220 symptoms of acute respiratory diseases is a critical parameter to estimate the true 221 number of COVID-19 cases in community. Accordingly, the daily number 476 of COVID-19 cases by symptom onset date was preferred to the aggregated 477 cumulative data.
    keywords: cases; copyright holder; funder; license; medrxiv preprint; peer review; preprint; september; version
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        item: #2068 of 7819
          id: cord-275858-46jzw94p
      author: Leung, Janice M.
       title: COVID-19 and COPD
        date: 2020-08-13
       words: 3026
      flesch: 23
     summary: The epidemiological data emerging from China and other early epicentres have not yet provided the necessary granularity required to determine whether these medications are harmful or beneficial in COVID-19 patients with COPD. Because of the results of the RECOVERY trial, however, it is likely that dexamethasone will become standard of care treatment for COVID-19 patients including those with COPD.
    keywords: characteristics; china; clinical; copd; coronavirus; covid-19; disease; patients; sars
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        item: #2069 of 7819
          id: cord-275866-m89hgf41
      author: Li, Ping
       title: Clinical Features and Short-term Outcomes of Elderly Patients With COVID-19
        date: 2020-05-31
       words: 2361
      flesch: 49
     summary: The onset of dyspnea might help physicians identify the patients with poor prognosis.35.3% patients were classified as severe or even critical cases on admission. Although so far the overall mortality of COVID-19 is relatively low, the mortality of elderly patients is much higher.
    keywords: covid-19; death; disease; mortality; patients
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        item: #2070 of 7819
          id: cord-275867-qm7y3thy
      author: Hassan, Suzan B.
       title: COVID-19 and repeat visitation: Assessing the role of destination social responsibility, destination reputation, holidaymakers’ trust and fear arousal
        date: 2020-10-06
       words: 7339
      flesch: 36
     summary: Fear appeal favoring purchase behavior towards personal protective equipment The fear of COVID-19 scale: Development and initial validation Corporate social responsibility and CSR fit as predictors of corporate reputation: A global perspective Customer loyalty and complex services: The impact of corporate image on quality, customer satisfaction and loyalty for customers with varying degrees of service expertise Antecedents of tourism destination reputation: The mediating role of familiarity Determinants of trust towards tourist destinations Evaluating structural equation models with unobservable variables and measurement error The role of coping appraisal in reactions to fear appeals: Do we need threat information Impact of service quality and trust on repurchase intentions-the case of Pakistan airline industry Extending the theory of planned behavior to predict tourism destination revisit intention The biology of fear and anxiety-related behaviors Study on the relationships among destination social responsibility, destination reputation, destination identification and tourism loyalty How does perceived destination social responsibility impact revisit intentions: The mediating roles of destination preference and relationship quality The effect of destination social responsibility on tourist environmentally responsible behavior: Compared analysis of first-time and repeat tourists How do destination social responsibility strategies affect tourists' intention to visit?
    keywords: covid-19; destination; dsr; fear; intention; reputation; research; revisit; tourism; trust
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        item: #2071 of 7819
          id: cord-275880-d53xe5oh
      author: Halepas, Steven
       title: A Pinch of Prevention is Worth a Pound of Cure: Proactive Dentistry in the Wake of COVID-19.
        date: 2020-04-09
       words: 1296
      flesch: 59
     summary: Concentrating on emergency dental care will allow us to care for our emergency patients and alleviate the burden that dental emergencies would place on hospital emergency departments. If a patient is suspected to have COVID-19 and emergency dental care is indicated, it is recommended to perform the dental treatment in a negative pressure room or airborne infection isolation room.
    keywords: aids; care; covid-19; dentistry
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        item: #2072 of 7819
          id: cord-275897-j9cwlzxu
      author: Hashmi, Ali M.
       title: New Horizons: COVID-19 and the Burden of Neuropsychiatric Illness in Pakistan
        date: 2020-05-17
       words: 2527
      flesch: 46
     summary: This manuscript reviews the current state of knowledge about the burden of mental illness and assesses the impact of COVID-19 illness on mental health in Pakistan. We also did a literature search on the effects of COVID-19 illness on mental health and the psychosocial effects of COVID-19 and other Corona virus related illnesses such as SARS-CoV and MERS-CoV. Data from the studies obtained was utilized to extrapolate the anticipated effects of COVID-19 illness on healthcare workers, COVID-19 patients and the general public in Pakistan.
    keywords: covid-19; health; healthcare; illness; illnesses; pakistan
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        item: #2073 of 7819
          id: cord-275915-fz16sylv
      author: Liu, Zi-Han
       title: Migrant workers in China need emergency psychological interventions during the COVID-19 outbreak
        date: 2020-08-19
       words: 1428
      flesch: 38
     summary: In addition, free online education on mental health is useful to improve their awareness of mental health and help them seek help from mental health services [4] . However, lack of knowledge of mental health, low education level, perceived stigma and limited access to online information make it hard for migrant workers to benefit from these services.
    keywords: covid-19; health; mental; workers
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        item: #2074 of 7819
          id: cord-275924-mmcszoxb
      author: Drew, David A.
       title: Rapid implementation of mobile technology for real-time epidemiology of COVID-19
        date: 2020-04-06
       words: 2188
      flesch: 37
     summary: Although several digital collection tools for COVID-19 symptoms have been developed and launched in the U.S., including some in partnership with government health agencies such as the CDC, these applications have largely been configured to offer a single assessment of symptoms to tailor recommendations for further 15 evaluation. Through pushed software updates, we can add or modify questions in real-time to test emerging hypotheses about COVID-19 symptoms and treatments.
    keywords: covid-19; data; health; license; medrxiv; preprint
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        item: #2075 of 7819
          id: cord-275946-ofd2ipvs
      author: Cheng, Matthew P.
       title: Serodiagnostics for Severe Acute Respiratory Syndrome–Related Coronavirus-2: A Narrative Review
        date: 2020-06-04
       words: 5287
      flesch: 27
     summary: The time course of the immune response to experimental coronavirus infection of man The convalescent sera option for containing COVID-19 Use of convalescent plasma therapy in SARS patients in Hong Kong The feasibility of convalescent plasma therapy in severe COVID-19 patients: a pilot study Effectiveness of convalescent plasma therapy in severe COVID-19 patients Testing an old therapy against a new disease: convalescent plasma for COVID-19 Deployment of convalescent plasma for the prevention and treatment of COVID-19 Anti-influenza immune plasma for the treatment of patients with severe influenza A: a randomised, double-blind, phase 3 trial Anti-influenza hyperimmune intravenous immunoglobulin for adults with influenza A or B infection (FLU-IVIG): a double-blind, randomised, placebo-controlled trial Subunit vaccines against emerging pathogenic human coronaviruses SARS CoV subunit vaccine: antibody-mediated neutralisation and enhancement Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection Prospects for a MERS-CoV spike vaccine A pneumonia outbreak associated with a new coronavirus of probable bat origin Current status of epidemiology, diagnosis, therapeutics, and vaccines for novel coronavirus disease 2019 (COVID-19) Analysis and interpretation of the data Drafting of the article Administrative, technical, or logistic support: C. Caya. The figure shows a decision tree for interpreting antibody test results by symptomatology (symptomatic, postsymptomatic, asymptomatic or subclinical) and whether the patient is a suspected case.
    keywords: antibodies; antibody; assays; cov-2; covid-19; disease; infection; patients; sars; serologic; studies; test
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        item: #2076 of 7819
          id: cord-275974-uqd30v7b
      author: Shorfuzzaman, Mohammad
       title: MetaCOVID: A Siamese neural network framework with contrastive loss for n-shot diagnosis of COVID-19 patients
        date: 2020-10-17
       words: 5441
      flesch: 44
     summary: The shortage of COVID-19 CXR images brings substantial challenges in developing tools for effectively diagnosing COVID-19 cases using deep learning based techniques. Our model achieves 95.6% accuracy and AUC of 0.97 in diagnosing COVID-19 from CXR images even with a limited number of training samples.
    keywords: covid-19; cxr; dataset; diagnosis; images; learning; loss; model; network; shot; training
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        item: #2077 of 7819
          id: cord-275978-pezm1tnw
      author: Riccardo, Flavia
       title: Epidemiological characteristics of COVID-19 cases in Italy and estimates of the reproductive numbers one month into the epidemic
        date: 2020-04-11
       words: 5551
      flesch: 49
     summary: key: cord-275978-pezm1tnw authors: Riccardo, Flavia; Ajelli, Marco; Andrianou, Xanthi; Bella, Antonino; Del Manso, Martina; Fabiani, Massimo; Bellino, Stefania; Boros, Stefano; Mateo Urdiales, Alberto; Marziano, Valentina; Rota, Maria Cristina; Filia, Antonietta; D'Ancona, Fortunato (Paolo); Siddu, Andrea; Punzo, Ornella; Trentini, Filippo; Guzzetta, Giorgio; Poletti, Piero; Stefanelli, Paola; Castrucci, Maria Rita; Ciervo, Alessandra; Di Benedetto, Corrado; Tallon, Marco; Piccioli, Andrea; Brusaferro, Silvio; Rezza, Giovanni; Merler, Stefano; Pezzotti, Patrizio title: Epidemiological characteristics of COVID-19 cases in Italy and estimates of the reproductive numbers one month into the epidemic date: 2020-04-11 journal: nan DOI: 10.1101/2020.04.08.20056861 sha: doc_id: 275978 cord_uid: pezm1tnw Background Due to the high concordance (99%) among confirmation results with the engaged laboratories, the policy was then changed allowing selected Regions with demonstrated confirmation capacity to directly confirm COVID-19 cases (17) .
    keywords: age; cases; covid-19; data; disease; epidemic; italy; license; number; preprint; regions; transmission
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        item: #2078 of 7819
          id: cord-275979-cx2h5bsw
      author: Scutelnic, Adrian
       title: Vascular Events, Vascular Disease and Vascular Risk Factors—Strongly Intertwined with COVID-19
        date: 2020-10-08
       words: 6757
      flesch: 42
     summary: At present, current guidelines do not recommend to prophylactically prescribe ACEIs/ARBs to decrease COVID-19 infection risk and to improve outcome of COVID-19, and they do not recommend to switch an established treatment for these antihypertensive drugs in COVID-19 patients Studies have found pathological laboratory test results in COVID-19 patients, especially in those with severe COVID-19, such as elevated leukocyte counts, reduced lymphocyte counts and elevated levels of C-reactive protein, Ddimer levels, ferritin and lactate dehydrogenase, indicating hypercoagulability Patient with ischaemic stroke because of large vessel occlusion.
    keywords: analysis; covid-19; diabetes; disease; factors; patients; risk; sars; stroke; study
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        item: #2079 of 7819
          id: cord-276013-8dhqa2gj
      author: Luo, Yung-Hung
       title: Overview of coronavirus disease 2019: Treatment updates and advances
        date: 2020-08-17
       words: 3776
      flesch: 40
     summary: Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Patients of COVID-19 may benefit from sustained lopinavir-combined regimen and the increase of eosinophil may predict the outcome of COVID-19 progression Arbidol combined with LPV/r versus LPV/r alone against corona virus disease 2019: a retrospective cohort study A trial of lopinavirritonavir in adults hospitalized with severe Covid-19 A case series of children with 2019 novel coronavirus infection: clinical and epidemiological features Public health might be endangered by possible prolonged discharge of SARS-CoV-2 in stool Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Baricitinib as potential treatment for 2019-nCoV acute respiratory disease Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Chloroquine is a potent inhibitor of SARS coronavirus infection and spread In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Urgent guidance for navigating and circumventing the QTcprolonging and torsadogenic potential of possible pharmacotherapies for coronavirus disease 19 (COVID-19) Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis Characteristics of Arbidolresistant mutants of influenza virus: implications for the mechanism of anti-influenza action of Arbidol PALM Writing Group; PALM Consortium Study Team. 2 Taiwan is only 130 km from the coast of mainland China; due to its geographical proximity and the frequent travel between these two areas, Taiwan was initially predicted to exhibit the second highest number of COVID-19 patients.
    keywords: 2019; coronavirus; cov-2; covid-19; disease; patients; pneumonia; sars; treatment
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        item: #2080 of 7819
          id: cord-276014-inv3hsbr
      author: Wijngaards, Indy
       title: Extraversion Moderates the Relationship Between the Stringency of COVID-19 Protective Measures and Depressive Symptoms
        date: 2020-10-02
       words: 3766
      flesch: 37
     summary: As the empirical evidence for this claim is lacking, this study tested the hypothesis that extraversion moderates the relationship between the stringency of COVID-19 protective measures and depressive symptoms. An increasing degree of stringency of COVID-19 protective measures is typically accompanied by increased social distancing, the limiting of face-to-face contact with others by keeping space between oneself and other people outside of one's home.
    keywords: country; covid-19; et al; measures; stringency; symptoms
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        item: #2081 of 7819
          id: cord-276044-z7rupgfo
      author: Di Crosta, Adolfo
       title: Individual Differences, Economic Stability, and Fear of Contagion as Risk Factors for PTSD Symptoms in the COVID-19 Emergency
        date: 2020-09-08
       words: 5712
      flesch: 40
     summary: Furthermore, the present study aims to identify the risk factors for high PTSD symptoms, including individual differences and subjective perception of both economic and psychological aspects. Specifically, we adopted the optimal cut-off of 33 (Creamer et al., 2003) to distinguish between low PTSD symptoms (low-PTSDs) and high PTSD symptoms (high-PTSDs).
    keywords: contagion; covid-19; et al; factors; impact; pandemic; ptsd; stress; study; symptoms
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        item: #2082 of 7819
          id: cord-276061-7b8h2sjw
      author: Zammit, M
       title: A rise in facial nerve palsies during the coronavirus disease 2019 pandemic
        date: 2020-10-01
       words: 2480
      flesch: 49
     summary: A retrospective review was conducted of VIIth cranial nerve palsies from January to June 2020 and the findings were compared to those cases reviewed in the previous year. Patients with VIIth cranial nerve palsies were retrospectively reviewed from 1st January to 30th June 2020.
    keywords: cent; covid-19; nerve; palsy; patients
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        item: #2083 of 7819
          id: cord-276083-ds0f0ois
      author: Pelicioni, Paulo H.S.
       title: COVID-19 will severely impact older people's lives, and in many more ways than you think!
        date: 2020-05-01
       words: 1018
      flesch: 43
     summary: Novel coronavirus (COVID-19) epidemic: what are the risks for older patients? SARS CoV-2 (COVID-19): lessons to be learned by Brazilian Physical Therapists Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient Scientific and ethical basis for socialdistancing interventions against COVID-19 Reduced physical activity in young and older adults: metabolic and musculoskeletal implications Effects of 3 months of detraining on functional fitness and quality of life in older adults who regularly exercise Neighborhood, social isolation and mental health outcome among older people in Ghana Social isolation, loneliness, and all-cause mortality in older men and women The problems of vitamin d insufficiency in older people Falls in Parkinson's disease subtypes: risk factors, locations and circumstances Sedentary behavior: barriers and facilitators among older adults after hip fracture surgery. COVID-19 can lead to pneumonia, acute respiratory distress syndrome, and other health problems that can lead to poor prognoses, including death, especially in older people.
    keywords: isolation; people; social
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        item: #2084 of 7819
          id: cord-276090-n8c2jpr6
      author: Patel, Hiren N.
       title: Cerebellar Infarction Requiring Surgical Decompression in patient with COVID 19 Pathological Analysis, Brief Review
        date: 2020-07-29
       words: 2875
      flesch: 36
     summary: Larger studies will be helpful to examine the impact of diabetes in COVID-19 patients as a risk factor for development of anti-phospholipid antibodies, coagulopathy and stroke. There are currently ten clinical trials underway worldwide as per clinicaltrials.gov that are looking at the efficacy of dexamethasone in COVID-19 patients.
    keywords: cov-2; covid-19; disease; patient; sars; stroke; thrombosis
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        item: #2085 of 7819
          id: cord-276132-tv5y1eqc
      author: Ray, Upasana
       title: COVID-19: The Impact in Oncology Care
        date: 2020-10-23
       words: 5705
      flesch: 33
     summary: The crisis stage deals with when the system over surpluses with the COVID-19 cases and deprived of its ability to provide cancer patient care. With the increasing risk of cancer patients acquiring infection during receiving the essential care, the debate ensues on how to balance the risk factors and benefits out of the oncologic emergencies in cancer patients.
    keywords: cancer; cancer patients; care; coronavirus; covid-19; disease; guidelines; health; infection; pandemic; patients; risk; treatment
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        item: #2086 of 7819
          id: cord-276150-hp174yft
      author: Basnet, Sangita
       title: COVID-19 Containment Efforts of a Low-Resource Nation: The First Four Months in Nepal
        date: 2020-07-01
       words: 3324
      flesch: 52
     summary: WHO coronavirus disease (COVID-19) dashboard The World Bank in Nepal Air medical evacuation of Nepalese citizen during epidemic of COVID-19 from Wuhan to Nepal The first 2019 novel coronavirus case in Nepal COVID-19 Nepal: preparedness and response plan (NPRP) A survey of adult intensive care units in Kathmandu valley Hospitals outside Kathmandu ill-prepared to fight coronavirus outbreak Ministry of Health and Population. Nepal COVID-19 dashboard Asymptomatic patients to be quarantined or sent home as ministry expects 1,000 cases in a week Human Resources for Health (HRH) and challenges in Nepal Distribution and skill mix of health workforce in Nepal The Asia Foundation.
    keywords: cases; coronavirus; covid-19; disease; health; individuals; nepal; quarantine
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        item: #2087 of 7819
          id: cord-276177-hhmd8ilk
      author: Islam, Abu Reza Md. Towfiqul
       title: Are meteorological factors enhancing COVID-19 transmission in Bangladesh? Novel findings from a compound Poisson generalized linear modeling approach
        date: 2020-10-28
       words: 6433
      flesch: 46
     summary: Therefore, the results imply that AH, TDN, and MRH are the key contributing climatic variables for daily COVID-19 cases across Bangladesh. In this study, the change in daily COVID-19 cases has a strong association with AH and RH, which move southward to increase easterlies.
    keywords: bangladesh; cases; covid-19; factors; humidity; lag; meteorological; temperature
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        item: #2088 of 7819
          id: cord-276181-5gh0i394
      author: Eimer, J.
       title: Tocilizumab shortens time on mechanical ventilation and length of hospital stay in patients with severe COVID-19: a retrospective cohort study.
        date: 2020-07-30
       words: 1553
      flesch: 41
     summary: Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region Abnormal pulmonary function in COVID-19 patients at time of hospital discharge Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19 Impact of low dose tocilizumab on mortality rate in patients with COVID-19 related pneumonia Effective treatment of severe COVID-19 patients with tocilizumab Long-term complications of critical care Costs of Providing Infusion Therapy for Rheumatoid Arthritis in a Hospital-based Infusion Center Setting Alternate corresponding author / proof reader Senior Consultant in Infectious Diseases Phone None. key: cord-276181-5gh0i394 authors: Eimer, J.; Vesterbacka, J.; Svensson, A.-K.; Stojanovic, B.; Wagrell, C.; Sonnerborg, A.; Nowak, P. title: Tocilizumab shortens time on mechanical ventilation and length of hospital stay in patients with severe COVID-19: a retrospective cohort study.
    keywords: covid-19; patients; tocilizumab
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        item: #2089 of 7819
          id: cord-276194-4sfc7hal
      author: Vijayvargiya, Prakhar
       title: In Reply–The “Perfect Cytokine Storm” of COVID-19
        date: 2020-05-29
       words: 796
      flesch: 34
     summary: key: cord-276194-4sfc7hal authors: Vijayvargiya, Prakhar; Garrigos, Zerelda Esquer; Castillo Almeida, Natalia E.; Gurram, Pooja R.; Stevens, Ryan W.; Razonable, Raymund R. title: In Reply–The “Perfect Cytokine Storm” of COVID-19 date: 2020-05-29 journal: Mayo Clin Proc DOI: 10.1016/j.mayocp.2020.05.016 sha: doc_id: 276194 cord_uid: 4sfc7hal nan To the Editor:We read with great interest the letter by Testori regarding our Review article Treatment Considerations for COVID-19: A Critical Review of the Evidence (or Lack Thereof), 1 Testori pointed out the important association of pro-inflammatory cytokines in the pathogenesis of Coronavirus disease 2019 , which could account for the worse outcome in older individuals. The Lancet Financial support and conflict of interest disclosure: RRR serves as the principal investigator on clinical trials for tocilizumab and sarilumab.
    keywords: covid-19; review; trial
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        item: #2090 of 7819
          id: cord-276199-akoxd44f
      author: DEFAR, A.
       title: Knowledge, Practice and associated factors towards the Prevention of COVID-19 among high-risk groups: A cross-sectional study in Addis Ababa, Ethiopia
        date: 2020-08-16
       words: 4974
      flesch: 50
     summary: Our study revealed that having good knowledge on the transmission and prevention of COVID-19 was found to be associated with good practices on COVID-19 prevention. The global community is struggling to slow down and eventually halt the spread of COVID-19 that has claimed thousands of lives and sickened tens of thousands through improving the knowledge and practice of COVID-19 prevention methods, testing and screening (8, 9) .
    keywords: covid-19; health; knowledge; license; practice; preprint; prevention; study; transmission
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        item: #2091 of 7819
          id: cord-276204-ibmnuj5u
      author: Ratten, Vanessa
       title: Covid-19 and entrepreneurship education: Implications for advancing research and practice
        date: 2020-10-20
       words: 7878
      flesch: 36
     summary: For example, Zhang and Cain (2017) found that more than 50% of entrepreneurship education students intended to become entrepreneurs after finishing their courses. key: cord-276204-ibmnuj5u authors: Ratten, Vanessa; Jones, Paul title: Covid-19 and entrepreneurship education: Implications for advancing research and practice date: 2020-10-20 journal: nan DOI: 10.1016/j.ijme.2020.100432 sha: doc_id: 276204 cord_uid: ibmnuj5u This article aims at critically examining the linkage between entrepreneurship education and COVID-19 in order to help understand future research and practice paths.
    keywords: business; covid-19; crisis; education; entrepreneurship; impact; learning; management; means; pandemic; research; skills; students; way
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        item: #2092 of 7819
          id: cord-276225-tv70aakj
      author: Musolino, Anna Maria
       title: Lung Ultrasound in Children with COVID-19: Preliminary Findings
        date: 2020-05-03
       words: 2370
      flesch: 40
     summary: (Soldati et al. , 2020b task forces on the use of LUS in COVID-19 have provided the physical bases and LUS patterns in COVID-19 patients, suggesting that LUS can be a useful tool to diagnose and monitor COVID-19 pneumonia. According to our experience, the routine use of LUS in the evaluation of children with suspected or confirmed COVID-19, when performed by clinicians with documented experience in LUS, was useful in diagnosing and monitoring pediatric COVID-19 pneumonia, reducing unnecessary radiation/sedation in children and exposure of health care workers to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
    keywords: children; covid-19; lung; lus
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        item: #2093 of 7819
          id: cord-276234-2nkeq4ud
      author: Siedlecki, Jakob
       title: COVID-19: Ophthalmological Aspects of the SARS-CoV 2 Global Pandemic
        date: 2020-05-06
       words: 3707
      flesch: 39
     summary: Indeed, ophthalmologists seem to rank among the medical specialties with the highest risk for COVID-19 infection, probably due to close patient contact during examination, e.g., at the slit lamp In a recent survey of ophthalmology practitioners in the UK, 80 % of participants stated that they felt at high risk of COVID-19 transmission
    keywords: coronavirus; covid-19; disease; eye; ophthalmology; pandemic; patients; recommendations; sars; symptoms; transmission
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        item: #2094 of 7819
          id: cord-276237-zqtjjyoq
      author: Sundar, K. R. Shyam
       title: COVID-19 and State Failure: A Double Whammy for Trade Unions and Labour Rights
        date: 2020-09-14
       words: 2198
      flesch: 46
     summary: Trade unions need to do a lot of work to stay relevant even as they challenged more stridently by neo-liberal politics. Request for Coverage in Media Letter to the President of India Urgent Issues of Scheme Workers in the Context of COVID-19 Pandemic Strike Notice by NPCU to the Secretary Press Statement by BMS announcing Nationwide Agitation in Solidarity with the Fight Against the Anti-Worker Ordinances of UP, MP, Gujarat, and also other Labour Issues Sacrificing Workers on Altar of development Letter to Prime Minister: Not to Repeal Inter-State Migrant Workmen Act Ministry of Labour and Employment, Termination and wage cut (11th Letter) by CITU Joint Opposition to any move to amend Factories Act Modi govt says suspension of labour laws not reform, raises concern over states changing laws, The Print Indian factory workers protest after 'H&M cancels orders' leaving 1,000 jobless, Independent Ornella 2020. Trade unions argue that during the lockdown period, the state should assume full control and even responsibility of the economy and welfare of the workers.
    keywords: covid-19; india; labour; state; trade; unions; workers
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        item: #2095 of 7819
          id: cord-276238-2hv46ftk
      author: Ing, Richard J.
       title: The role of helmet-delivered noninvasive pressure support ventilation in COVID-19 patients
        date: 2020-05-08
       words: 3073
      flesch: 42
     summary: The respiratory support requirements for COVID-19 patients with L-type atypical respiratory ARDS physiology may require different respiratory support principles than that usually provided to patients presenting with the typical H-Type classic ARDS. Mortality among COVID-19 patients over 65 years of age in the Seattle was at least 62%.
    keywords: covid-19; cpap; helmet; intubation; patients; support; ventilation
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        item: #2096 of 7819
          id: cord-276241-4g6pa7kz
      author: Yurttaş, Berna
       title: Characteristics and outcomes of Behçet’s syndrome patients with Coronavirus Disease 2019: a case series of 10 patients
        date: 2020-07-09
       words: 1738
      flesch: 51
     summary: Mild or moderate Covid-19 Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: an updated analysis Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Incidence of venous thromboembolism in hospitalized patients with COVID-19 Incidence of COVID-19 in a cohort of adult and paediatric patients with rheumatic diseases treated with targeted biologic and synthetic disease-modifying anti-rheumatic drugs SARS-CoV-2 infection among patients with systemic autoimmune diseases Behçet syndrome: a contemporary view Phenotypes in Behçet's syndrome Update on the treatment of Behçet's syndrome Sensitivity of chest CT for COVID-19: comparison to RT-PCR Clinical features of rheumatic patients infected with COVID-19 in Wuhan, China An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19 Characteristics and outcomes of recipients of heart transplant with coronavirus disease 2019 Colchicine as a potent anti-inflammatory treatment in COVID-19: can we teach an old dog new tricks? Thromboembolic events may occur in hospitalized patients receiving thrombo-prophylaxis either in general ward conditions or in ICU [4] [5] [6] [7] .
    keywords: case; covid-19; disease; patients
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        item: #2097 of 7819
          id: cord-276249-9opsg7p2
      author: Roberto, Katrina T.
       title: Electroencephalographic findings in COVID-19 patients: A systematic review
        date: 2020-09-15
       words: 3124
      flesch: 35
     summary: key: cord-276249-9opsg7p2 authors: Roberto, Katrina T.; Espiritu, Adrian I.; Fernandez, Marc Laurence L.; Gutierrez, Josephine C. title: Electroencephalographic findings in COVID-19 patients: A systematic review date: 2020-09-15 journal: Seizure DOI: 10.1016/j.seizure.2020.09.007 sha: doc_id: 276249 cord_uid: 9opsg7p2 BACKGROUND: Further research on the relationship of the EEG findings to the clinical state and short- or long-term prognosis of COVID-19 patients may be conducted to help clinicians discern which patients would necessitate an EEG procedure and would eventually require treatment.
    keywords: cases; covid-19; eeg; findings; patients; review; studies
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        item: #2098 of 7819
          id: cord-276264-wgzh3f5m
      author: Navlakha, S.
       title: Projecting COVID-19 disease severity in cancer patients using purposefully-designed machine learning
        date: 2020-08-25
       words: 4669
      flesch: 48
     summary: Using clinical variables only collected on or before a patient's COVID-19 positive date (time zero), we sought to classify patients into one of three possible future outcomes: Severe-early (the patient required high levels of oxygen support within 3 days of being tested positive for COVID-19), Severe-late (the patient required high levels of oxygen after 3 days), and Non-severe (the patient never required oxygen support). Critically, classification accuracy is highest when using a potpourri of clinical variables -- including patient demographics, pre-existing diagnoses, laboratory and radiological work, and underlying cancer type -- suggesting that COVID-19 in cancer patients comes with numerous, combinatorial risk factors.
    keywords: cancer; covid-19; medrxiv; model; patients; preprint; review; variables
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        item: #2099 of 7819
          id: cord-276267-77903fld
      author: Al‐Ani, Aysha H.
       title: Review article: prevention, diagnosis and management of COVID‐19 in the IBD patient
        date: 2020-05-26
       words: 5501
      flesch: 30
     summary: The clinical impact of coronavirus infection in patients with hematologic malignancies and hematopoietic stem cell transplant recipients Risk factors for opportunistic infections in patients with inflammatory bowel disease Clinical assessment of risk factors for infection in inflammatory bowel disease patients Methods to avoid infections in patients with inflammatory bowel disease Increased incidence of systemic serious viral infections in patients with inflammatory bowel disease associates with active disease and use of thiopurines Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths Letter: Covid-19, and vitamin D Letter: Covid-19 and vitamin D-authors' reply Quantitative proteomic analysis reveals the deregulation of nicotinamide adenine dinucleotide metabolism and CD38 in inflammatory bowel disease Protection of 318 inflammatory bowel disease patients from the outbreak and rapid spread of COVID-19 infection in Wuhan Secure-IBD Database Public Data Update Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China CDC_AA_refVa l=https %3A%2F%2Fwww.cdc.gov%2F-cor onavi rus%2F201 9-ncov%2Fcli nical -crite ria Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines SARS: systematic review of treatment effects Corticosteroid therapy for critically Ill patients with middle east respiratory syndrome The effect of corticosteroids on mortality of patients with influenza pneumonia: a systematic review and meta-analysis Factors associated with psychosis among patients with severe acute respiratory syndrome: a case-control study Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients Glucocorticoid-induced diabetes in severe acute respiratory syndrome: the impact of high dosage and duration of methylprednisolone therapy Relationship between glucocorticoid receptor and deficiency syndrome and the regulation of traditional Chinese medicine Increased risk of influenza and influenza-related complications among 140,480 patients with inflammatory bowel disease Increased risk of pneumonia among patients with inflammatory bowel disease Prevention of infection caused by immunosuppressive drugs in gastroenterology The historical role and contemporary use of corticosteroids in inflammatory bowel disease Budesonide for maintenance of remission in Crohn's disease Efficacy and safety of oral beclomethasone dipropionate in ulcerative colitis: a systematic review and meta-analysis Oral prolonged release beclomethasone dipropionate and prednisone in the treatment of active ulcerative colitis: results from a double-blind, randomized, parallel group study Comparative safety of systemic and low-bioavailability steroids in inflammatory bowel disease: Systematic review and network meta-analysis Risk of serious and opportunistic infections associated with treatment of inflammatory bowel diseases Incidence of benign upper respiratory tract infections, HSV and HPV cutaneous infections in inflammatory bowel disease patients treated with azathioprine Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus Risk of infection with methotrexate therapy in inflammatory diseases: a systematic review and meta-analysis Methotrexate use and risk of lung disease in psoriasis, psoriatic arthritis, and inflammatory bowel disease: systematic literature review and meta-analysis of randomised controlled trials Serious infection and mortality in patients with Crohn's disease: more than 5 years of follow-up in the TREAT registry Risk for overall infection with anti-TNF and anti-integrin agents used in IBD: a systematic review and meta-analysis Comparative risk of serious infections with biologic and/or immunosuppressive therapy in patients with inflammatory bowel diseases: a systematic review and meta-analysis Anti-TNF-alpha therapy for patients with sepsis: a systematic meta-analysis Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection Ustekinumab as induction and maintenance therapy for Crohn's disease Risk of serious infection with biologic and systemic treatment of psoriasis: results from the psoriasis longitudinal assessment and registry IM-UNITI: three-year efficacy, safety, and immunogenicity of ustekinumab treatment of Crohn's disease Systematic review: the safety of vedolizumab for the treatment of inflammatory bowel disease Safety profile of biologic drugs in the therapy of Crohn disease: a systematic review and network meta-analysis Safety profile of biologic drugs in the therapy of ulcerative colitis: a systematic review and network meta-analysis The safety of vedolizumab for ulcerative colitis and Crohn's disease Differential expression of adhesion molecules and chemokines between nasal and small intestinal mucosae: implications for T-and sIgA+ B-lymphocyte recruitment Switch to adalimumab in patients with Crohn's disease controlled by maintenance infliximab: prospective randomised SWITCH trial Herpes zoster infection in patients with ulcerative colitis receiving tofacitinib Safety and efficacy of tofacitinib for up to 9.5 years in the treatment of rheumatoid arthritis: final results of a global, open-label, long-term extension study Tofacitinib as induction and maintenance therapy for ulcerative colitis Growing evidence of the safety of JAK inhibitors in patients with rheumatoid arthritis Real-world experience with tofacitinib in IBD at a Tertiary Center COVID-19: combining antiviral and anti-inflammatory treatments Guidance for discharge and ending isolation in the context of widespread community transmission of COVID-19 -first update Infection-related hospitalizations are associated with increased mortality in patients with inflammatory bowel diseases Nonpharmaceutical measures for pandemic influenza in nonhealthcare settings-social distancing measures Effectiveness of workplace social distancing measures in reducing influenza transmission: a systematic review Virtually perfect? In China healthcare workers made up 3.5% of COVID-19 patients and Italy have reported that 20% of its responding healthcare work force is being infected.
    keywords: bowel; clinical; coronavirus; cov-2; covid-19; disease; ibd; infection; patients; review; risk; sars; transmission; treatment
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        item: #2100 of 7819
          id: cord-276295-0w3jz31k
      author: Chai, A.
       title: Re: Testing recommendation for COVID-19 (SARS-CoV-2) in patients planned for surgery - continuing the service and ‘suppressing’ the pandemic
        date: 2020-05-11
       words: 638
      flesch: 59
     summary: This is especially in light of the latest NHS plans for COVID-19 free sites. We thank the editorial team in providing an excellent overview with regards to testing for COVID-19 in pre-op surgical patients.
    keywords: covid-19; patients
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        item: #2101 of 7819
          id: cord-276300-6xy8bwfl
      author: Sahoo, Swapnajeet
       title: Lived experiences of the Corona Survivors (patients admitted in COVID wards): A Narrative real-life documented summaries of internalized guilt, shame, stigma, anger
        date: 2020-05-30
       words: 2545
      flesch: 55
     summary: This led to the involvement of mental health professionals to provide mental health support through videoconferencing/telephonically. All these issues suggest that mental health is taking a big toll on the people diagnosed with COVID-19 infection and admitted to the COVID wards.
    keywords: covid-19; health; infection; issues; patients
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        item: #2102 of 7819
          id: cord-276303-lgywz9ea
      author: Rello, Jordi
       title: COVID-19, steroids and other immunomodulators: The jigsaw is not complete
        date: 2020-10-25
       words: 1633
      flesch: 34
     summary: The Cochrane Database of Systematic Reviews Effect of corticosteroids on treatment failure among hospitalized patients with severe community-acquired pneumonia and high inflammatory response: a randomized clinical trial Efficacy and Safety of Corticosteroids for Persistent Acute Respiratory Distress Syndrome Methylprednisolone infusion in early severe ARDS: results of a randomized controlled trial Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017. In severe CAP, corticosteroids use has resurfaced owing specifically to a large recent RCT (6), which found less treatment failure when methylprednisolone was used as an adjunctive therapy in patients with severe CAP and high inflammatory response.
    keywords: covid-19; days; mortality; patients; trial
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        item: #2103 of 7819
          id: cord-276316-7ot9ds34
      author: Lei, Chunliang
       title: Factors associated with clinical outcomes in patients with Coronavirus Disease 2019 in Guangzhou, China
        date: 2020-10-14
       words: 2381
      flesch: 50
     summary: CONCLUSIONS: Most of COVID-19 patients in Guangzhou are mild/moderate, and presence of extrapulmonary virus and higher CD4/CD8 ratio are associated with higher risk of worse outcomes. 7 One of the main challenges for the clinicians is how to quickly identify COVID-19 patients at high risk for worse outcomes.
    keywords: cells; covid-19; patients
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        item: #2104 of 7819
          id: cord-276325-l26sdtxf
      author: Jheon, Sanghoon
       title: General thoracic surgery services across Asia during the 2020 COVID-19 pandemic
        date: 2020-05-12
       words: 4635
      flesch: 50
     summary: Since the first cluster outbreak associated with the Shincheonji occurred at Daegu on February 20, the number of confirmed COVID-19 cases has surged. This included: rapid deployment of five kinds of rapid test kit for SARS-CoV-2; provision of these diagnostic tests for free or at a low price; smartphone alerts about the movements of confirmed cases, allowing people to see how close they were to coronavirus patients; testing of all people who were exposed to confirmed COVID-19 patients and instructing them to self-isolate for two weeks; drivethrough coronavirus testing sites to help diagnose patients and keep them from infecting others in hospital waiting rooms; provision of extra medical supplies, army doctors, and medical volunteers to the epicenter of the outbreak in Daegu; and introducing a social distancing campaign.
    keywords: cases; covid-19; hospitals; number; outbreak; patients; services; surgery; thoracic
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        item: #2105 of 7819
          id: cord-276327-wyevh4xv
      author: Sheng, Calvin C
       title: Canakinumab to reduce deterioration of cardiac and respiratory function in SARS‐CoV‐2 associated myocardial injury with heightened inflammation (canakinumab in Covid‐19 cardiac injury: The three C study)
        date: 2020-08-24
       words: 3243
      flesch: 27
     summary: Coronavirus disease 2019 (COVID-19): situation report Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy Clinical characteristics of Covid-19 in New York city Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis Hydroxychloroquine in patients with COVID-19: an open-label, randomized, controlled trial A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 Compassionate use of remdesivir for patients with severe Covid-19 Remdesivir for the treatment of Covid-19 -preliminary report Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and lifethreatening COVID-19: a randomized clinical trial Dexamethasone in hospitalized patients with Covid-19 -preliminary report COVID-19 and the cardiovascular system Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical features of patients infected with 2019 novel coronavirus in Wuhan Community-Acquired Pneumonia-China Network. Association between cardiac injury and mortality in hospitalized patients infected with avian influenza a (H7N9) virus Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan China Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China Prognostic value of NT-proBNP in patients with severe COVID-19 Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) COVID-19: consider cytokine storm syndromes and immunosuppression.
    keywords: canakinumab; cardiac; clinical; covid-19; inflammation; injury; patients; study; trial
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        item: #2106 of 7819
          id: cord-276328-08ava9ni
      author: Kunutsor, Setor K.
       title: Hepatic manifestations and complications of COVID-19: A systematic review and meta-analysis
        date: 2020-06-21
       words: 461
      flesch: 21
     summary: Renal complications in COVID-19: A systematic review and meta-analysis Cardiovascular complications in COVID-19: A systematic review and meta-analysis Clinical course and mortality risk of severe COVID-19 Markers of liver injury and clinical outcomes in COVID-19 patients: A systematic review and meta-analysis Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19) Comorbid Chronic Diseases and Acute Organ Injuries Are Strongly Correlated with Disease Severity and Mortality among COVID-19 Patients: A Systemic Review and Meta-Analysis. (5, 6) Emerging data also suggests COVID-19 contributes to adverse hepatic manifestations such as acute hepatic injury.
    keywords: covid-19; injury
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        item: #2107 of 7819
          id: cord-276351-cv5th7hd
      author: Moorlag, Simone J.C.F.M.
       title: Safety and COVID-19 symptoms in individuals recently vaccinated with BCG: a retrospective cohort study
        date: 2020-08-05
       words: 1284
      flesch: 24
     summary: To investigate the safety of BCG vaccination, we retrospectively assessed coronavirus disease 2019 (COVID-19) and related symptoms in three cohorts of healthy volunteers who either received BCG in the last five years or not. BCG vaccination is not associated with increased incidence of symptoms during the COVID-19 outbreak in the Netherlands.
    keywords: bcg; covid-19; figure; immunity; vaccination
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        item: #2108 of 7819
          id: cord-276359-syr9av09
      author: Piva, Simone
       title: Clinical presentation and initial management critically ill patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Brescia, Italy
        date: 2020-04-14
       words: 3316
      flesch: 47
     summary: CONCLUSIONS: ICU patients with COVID-19 frequently have hypertension. This is the first reported cohort of ICU patients with COVID-19 from the Lombardy region.
    keywords: covid-19; icu; non; patients; physicians; scale; therapies; ventilation
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        item: #2109 of 7819
          id: cord-276374-i37ygb2z
      author: Deasy, Jacob
       title: Forecasting ultra-early intensive care strain from COVID-19 in England
        date: 2020-03-23
       words: 2981
      flesch: 44
     summary: By incorporating a 'delay to ICU' parameter within our model, that can take on negative values (thus indicating a diagnosis after ICU admission), we hope to have replicated the anecdotal experience of clinicians in these early phases of the pandemic; that a substantial proportion of patients are being con- forecast numbers as these data inform our standardised estimates of ICU cases from within each population [9] . Figure 2: Regional demographics and expected critical care demand per case of COVID-19, stratified by region and compared to ICU bed capacity per 100,000 people.
    keywords: capacity; cases; covid-19; data; icu; model; time
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        item: #2110 of 7819
          id: cord-276391-g43ktrj9
      author: Browne, Rodrigo A.V.
       title: Initial impact of the COVID-19 pandemic on physical activity and sedentary behavior in hypertensive older adults: An accelerometer-based analysis
        date: 2020-10-22
       words: 2904
      flesch: 44
     summary: Results Before COVID-19 pandemic participants presented: 5809 steps/day (SE = 366), 303.1 min/day (SE = 11.9) of light PA, 15.5 min/day (SE = 2.2) of moderate-vigorous PA, and 653.0 min/day (SE = 12.6) of SB. We highlight that the decreases in PA and the increases in SB levels occurred in a sample of hypertensive older adults who already had low PA (~5,800 steps/day, ~5 hour/day of light PA, and ~15 min/day of moderate-vigorous PA) and high SB (~11 hour/day) levels before the COVID-19 pandemic.
    keywords: covid-19; day; pandemic
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        item: #2111 of 7819
          id: cord-276392-m1bbt8bo
      author: Asyary, Al
       title: Sunlight exposure increased Covid-19 recovery rates: A study in the central pandemic area of Indonesia
        date: 2020-04-27
       words: 1837
      flesch: 48
     summary: Therefore, the death proportion of Covid-19 cases in Jakarta was 8.4% higher than the recovered proportion at 3.3%. Besides that, inadequate healthcare management, such as failure to provide early diagnosis and prompt treatment, would decrease the rate of recovery among Covid-19 patients (Greenhalgh et al., 2020; Hopman et al., 2020) .
    keywords: covid-19; jakarta; sunlight
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        item: #2112 of 7819
          id: cord-276401-zsim1pn2
      author: Kay, Emma Sophia
       title: From HIV to Coronavirus: AIDS Service Organizations Adaptative Responses to COVID-19, Birmingham, Alabama
        date: 2020-04-24
       words: 1368
      flesch: 42
     summary: Due to current cessation of community HIV testing and education events, prevention staff have temporarily been moved into client services. In addition, the increase in number of staff trained in client services has enabled BAO to reduce work schedules to allow employees to spend more days at home and reduce chance of exposure to COVID-19.
    keywords: bao; clients; covid-19; services
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        item: #2113 of 7819
          id: cord-276405-yfvu83r9
      author: Brat, Gabriel A.
       title: International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium
        date: 2020-08-19
       words: 5733
      flesch: 43
     summary: RESTful API The Genomics Research and Innovation Network: creating an interoperable, federated, genomics learning system Scalable collaborative infrastructure for a learning healthcare system (SCILHS): architecture SHRINE: enabling nationally scalable multi-site disease studies Overview of data collection and analysis The Shared Health Research Information Network (SHRINE): a prototype federated query tool for clinical data repositories Accrual to Clinical Trials (ACT): a clinical and translational science award consortium network A translational engine at the national scale: informatics for integrating biology and the bedside Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy An interactive web-based dashboard to track COVID-19 in real time Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal Laboratory abnormalities in patients with COVID-2019 infection Impact of selective mapping strategies on automated laboratory result notification to public health authorities Learning from the crowd in terminology mapping: the LOINC experience Standardizing laboratory data by mapping to LOINC Evaluating congruence between laboratory LOINC value sets for quality measures, public health reporting, and mapping common tests Early vision for the CTSA Program Trial Innovation Network: a perspective from the National Center for Advancing Translational Sciences Launching PCORnet, a national patient-centered clinical research network German medical informatics initiative The COVID-19 Global Rheumatology Alliance: collecting data in a pandemic Recent developments in clinical terminologies-SNOMED CT, LOINC, and RxNorm i2b2: Informatics for Integrating Biology & the Bedside CTSA ACT Network i2b2 and SHRINE Ontology with 1-1 SHRINE Adapter Mapping File (Github The Unified Medical Language System (UMLS): integrating biomedical terminology All authors approved the manuscript. Aggregate laboratory data have limited ability to identify general trends in the admitted population.
    keywords: countries; covid-19; data; day; diagnosis; disease; hospitals; laboratory; level; number; patients; sites; tests; time; values
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        item: #2114 of 7819
          id: cord-276428-oy8e2cpx
      author: Krishnan, Lakshmi
       title: Historical Insights on Coronavirus Disease 2019 (COVID-19), the 1918 Influenza Pandemic, and Racial Disparities: Illuminating a Path Forward
        date: 2020-06-05
       words: 5438
      flesch: 37
     summary: Unfortunately, this comes as no surprise to health equity researchers and historians of medicine and public health. However, those cities often greeted them with prejudice, stigma, segregationist policies, and violence, allegedly aimed at improving public health.
    keywords: americans; care; communities; community; covid-19; data; disease; disparities; health; influenza; pandemic; public; racial
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        item: #2115 of 7819
          id: cord-276438-nynri6my
      author: Lu, Jiade J.
       title: Experience of a Radiation Oncology Center Operating During the COVID-19 Outbreak
        date: 2020-04-10
       words: 1545
      flesch: 44
     summary: Anyone with a body temperature over 37.3 o C and pertinent contact/travel history is transferred to a fever clinic at a designated hospital (special clinics of major general hospitals established during the 2003 SARS epidemic to triage and treat patients with fever) to rule out COVID-19 infection. Cancer treatment under such circumstances is tremendously challenging because patients undergoing radiation or chemotherapy may be more susceptible to infection, especially because cancer treatments usually require extended and continuous courses.
    keywords: cancer; covid-19; hospital; patients
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        item: #2116 of 7819
          id: cord-276483-4yp4beuh
      author: Cooper, Isabella D
       title: Relationships between hyperinsulinaemia, magnesium, vitamin D, thrombosis and COVID-19: rationale for clinical management
        date: 2020-09-16
       words: 7899
      flesch: 29
     summary: mmol/L is a proxy marker for insulin levels being inside of a range that is likely to be nonpathological for the patient 77 and indicates physiological insulin homeostasis range. A single fasting blood sample may miss its peak; when possible, gold standard practice would be to take three samples, 5 min apart or to consider a 2-hour postprandial level, especially if fasting insulin levels are <180 pmol/L. 85
    keywords: blood; carbohydrate; covid-19; diabetes; glucose; haem; health; hyperglycaemia; hyperinsulinaemia; insulin; levels; management; patients; production; restriction; risk; vitamin
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        item: #2117 of 7819
          id: cord-276493-hoaxv5e0
      author: Jeong, Gi Uk
       title: Therapeutic Strategies Against COVID-19 and Structural Characterization of SARS-CoV-2: A Review
        date: 2020-07-14
       words: 5702
      flesch: 43
     summary: (Dai et al., 2020; Jin et al., 2020; Zhang et al., 2020b) . (Dai et al., 2020; Jin et al., 2020; Zhang et al., 2020b) .
    keywords: binding; coronavirus; cov-2; covid-19; et al; hace2; pro; protein; rbd; rna; sars; structure
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        item: #2118 of 7819
          id: cord-276524-th6eu11h
      author: Atallah, Bassam
       title: Thrombotic events following tocilizumab therapy in critically ill COVID-19 patients: a Façade for prognostic markers
        date: 2020-09-09
       words: 2636
      flesch: 38
     summary: key: cord-276524-th6eu11h authors: Atallah, Bassam; El Nekidy, Wasim; Mallah, Saad I.; Cherfan, Antoine; AbdelWareth, Laila; Mallat, Jihad; Hamed, Fadi title: Thrombotic events following tocilizumab therapy in critically ill COVID-19 patients: a Façade for prognostic markers date: 2020-09-09 journal: Thromb J DOI: 10.1186/s12959-020-00236-9 sha: doc_id: 276524 cord_uid: th6eu11h BACKGROUND: Hospitals in the Middle East Gulf region have experienced an influx of COVID-19 patients to their medical wards and intensive care units. Our quaternary care hospital has adapted to accommodate the influx by approximately doubling ICU bed capacity, and dedicating half of it for COVID-19 patients.
    keywords: admission; covid-19; day; heparin; markers; patient; tocilizumab
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        item: #2119 of 7819
          id: cord-276529-ol2c7f3x
      author: Ramasamy, Roshan
       title: Molecular mechanisms for thrombosis risk in Black people: a role in excess mortality from COVID‐19
        date: 2020-06-08
       words: 1496
      flesch: 35
     summary: 14 Thrombin generation was increased in Black people with or without DVT compared to White people, 14 suggesting that in both the UK and USA, some Black populations have higher thrombotic risk. [7] [8] [9] Increased D-dimer levels have been demonstrated in African-Americans without VTE, 10 which persist despite controlling for age, sex, VTE risk factors, medications and lifestyle.
    keywords: african; americans; covid-19; risk
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        item: #2120 of 7819
          id: cord-276538-q0v26rml
      author: Guasch, Emilia
       title: Recomendaciones prácticas en la paciente obstétrica con infección por COVID-19
        date: 2020-07-10
       words: 4836
      flesch: 43
     summary: En una paciente infectada con COVID 19, el momento de mayor riesgo de exposición de los profesionales al virus es el relacionado con la exposición y contacto directo con gotas provenientes de la vía aérea durante la manipulación de la misma, sobre todo durante la intubación y extubación traqueal (14) . 90% y en el caso de la gestante por debajo de 93%, respirando aire ambiente.
    keywords: analgesia; anestesia; anestesiólogo; atención; caso; cesárea; con; covid; covid-19; debe; del; epi; evitar; general; gestantes; infección; las; los; más; neuroaxial; pacientes; para; por; posible; protección; que; quirófano; recomendaciones; recomienda; riesgo; son; una; uso
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        item: #2121 of 7819
          id: cord-276549-r5l4pse8
      author: Dastoli, Stefano
       title: Are erythema multiforme and urticaria related to a better outcome of COVID‐19?
        date: 2020-06-09
       words: 453
      flesch: 39
     summary: Eosinophilic skin diseases: a comprehensive review Dermatology staff participate in fight against COVID-19 in China Clinical features of 85 fatal cases of COVID-19 from Wuhan: a retrospective observational study Clinical characteristics of 140 patients infected with SARS-COV-2 in Wuhan COVID-19, chronic inflammatory respiratory diseases and eosinophils-observations from reported clinical case series Eosinophil responses during COVID-19 infections and coronavirus vaccination Clinical and histopathological study of skin dermatoses in patients affected by COVID-19 infection in the Northern part of Italy Patients of COVID-19 may benefit from sustained lopinavir-combined regimen and the increase of eosinophil may predict the outcome of COVID-19 progression Characterization of acute acro-ischemic lesions in non-hospitalized patients: a case series of 132 patients during the COVID-19 outbreak Cutaneous manifestations in COVID-19: a first perspective 9 U not related to drug reaction was reported in up to 4% of COVID-19 patients, 10 In conclusion, we might suppose that EM and U, when associated to eosinophilia, could be related to a better outcome of COVID-19.
    keywords: covid-19; patients
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        item: #2122 of 7819
          id: cord-276592-dsilwfl1
      author: Chou, Calvin L
       title: How COVID-19 Disrupts—and Enhances—My Clinical Work
        date: 2020-04-08
       words: 1382
      flesch: 54
     summary: key: cord-276592-dsilwfl1 authors: Chou, Calvin L title: How COVID-19 Disrupts—and Enhances—My Clinical Work date: 2020-04-08 journal: J Patient Exp DOI: 10.1177/2374373520918739 sha: doc_id: 276592 cord_uid: dsilwfl1 nan Sitting in my office right before the start of my primary care clinic, I studied my list of patients for the day. The rapid change in how I interact with patients in this era of the COVID-19 pandemic feels dizzying.
    keywords: communication; covid-19; medical; patients
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        item: #2123 of 7819
          id: cord-276626-ujbmukj0
      author: Rascado Sedes, P.
       title: Plan de contingencia para los servicios de medicina intensiva frente a la pandemia COVID-19♦
        date: 2020-04-03
       words: 3896
      flesch: 45
     summary: En España, el primer caso se declaró el 31 de enero de 2020. En España, el primer caso se declaró el 31 de enero de 2020.
    keywords: cada; care; como; con; coronavirus; covid-19; debe; del; hospital; intensiva; las; los; medicina; pacientes; pandemia; para; personal; plan; por; que; recomienda; recursos; uci; una
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        item: #2124 of 7819
          id: cord-276630-qci7khki
      author: Lima, William Gustavo
       title: The potential of drug repositioning as a short-term strategy for the control and treatment of COVID-19 (SARS-CoV-2): a systematic review
        date: 2020-06-08
       words: 3740
      flesch: 46
     summary: Abidol and darunavir can effectively inhibit coronavirus Going global-Travel and the 2019 novel coronavirus Lopinavir/ritonavir: a review of its use in the management of HIV infection Screening of an FDA-approved compound library identifies four smallmolecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture Treatment With Lopinavir/Ritonavir or Interferon-β1b improves outcome of MERS-CoV infection in a nonhuman primate model of common marmoset Arbidol: a broad-spectrum antiviral compound that blocks viral fusion Arbidol as a broadspectrum antiviral: An update Antiviral activity of arbidol and its derivatives against the pathogen of severe acute respiratory syndrome in the cell cultures Therapeutic strategies to target the Ebola virus life cycle Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations The promising in vitro results of chloroquine and hydroxychloroquine have motivated the initiation of clinical studies of these substances ( Table 4) .
    keywords: activity; coronavirus; cov-2; covid-19; drugs; lopinavir; sars; studies
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        item: #2125 of 7819
          id: cord-276635-0ciy732e
      author: Nijjer, Sukhjinder Singh
       title: Optimal management of acute coronary syndromes in the era of COVID-19
        date: 2020-09-02
       words: 4489
      flesch: 44
     summary: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China Cardiovascular implications of fatal outcomes of patients with coronavirus disease Cardiac injury is associated with mortality and critically ill pneumonia in COVID-19: a metaanalysis Fourth universal definition of myocardial infarction Comparison of hospitalized patients with ARDS caused by COVID-19 and H1N1 Potential effects of coronaviruses on the cardiovascular system: a review SARS-CoV2: should inhibitors of the renin-angiotensin system be withdrawn in patients with COVID-19? Renin-Angiotensin system blockers and the COVID-19 pandemic: at present there is no evidence to abandon renin-angiotensin system blockers ESC guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation Long-Term outcome of a routine versus selective invasive strategy in patients with non-ST-segment elevation acute coronary syndrome a meta-analysis of individual patient data Association of treatment dose anticoagulation with in-hospital survival among hospitalized patients with COVID-19 Rivaroxaban in patients with a recent acute coronary syndrome ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of cardiology (ESC) An extended statement by the British cardiovascular intervention Society president regarding the COVID-19 pandemic EAPCI position statement on invasive management of acute coronary syndromes during the COVID-19 pandemic High thrombus burden in patients with COVID-19 presenting with ST-elevation myocardial infarction ST-Segment Elevation in Patients with Covid-19 -A Case Series Reperfusion of STEMI in the COVID-19 Era -Business as Usual? ► Patients with higher risk NSTEMI (dynamic ECG changes and elevated troponin) are best treated with revascularisation where possible.
    keywords: cardiac; care; covid-19; elevation; infarction; pandemic; patients; risk; stemi
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        item: #2126 of 7819
          id: cord-276641-40r4mitg
      author: Elkhouly, Enas A
       title: Should cancer treatment be continued during the COVID-19 pandemic? A single Egyptian institution experience
        date: 2020-07-23
       words: 3115
      flesch: 55
     summary: The aim of this article is based on the fact that the potential threat of COVID-19 to immunocompromised cancer patients as a result of their disease or the treatment delivered is thought to be significant, so it is of great importance to study the best measures to be used by oncology centres to prevent or limit the exposure of cancer patients to COVID-19 and to provide cancer treatment to patients in need, as safely and as correctly as possible. Cancer patients have weaker immune systems compared to the general population, both due to the disease itself and the treatment.
    keywords: cancer; covid-19; health; mcod; pandemic; patients; treatment; visits
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        item: #2127 of 7819
          id: cord-276676-lgt0rzob
      author: Moka, Eleni
       title: Best Practice in Cardiac Anesthesia during the COVID-19 Pandemic: Practical Recommendations
        date: 2020-07-03
       words: 5885
      flesch: 31
     summary: Strict measures and precautions for infection control should be implanted and must definitely be applied in the case of suspected/ confirmed COVID-19 cardiac surgery patients Cardiac surgery patients must always wear a N95/surgical mask, and at all times, and should be transported to the OR through a predesigned pathway.
    keywords: anesthesia; blood; cardiac; care; cases; coronavirus; covid-19; disease; equipment; health; infection; operations; pandemic; patients; surgery
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        item: #2128 of 7819
          id: cord-276711-y74zr7fn
      author: Winthrop, Kevin L
       title: To immunosuppress: whom, when and how? That is the question with COVID-19
        date: 2020-08-04
       words: 2456
      flesch: 35
     summary: We anxiously await the conclusion of ongoing sarilumab and tocilizumab studies, as presently it is unclear who might benefit, and when, from IL-6 inhibition. The authors explicitly and elegantly discuss the potential for such unmeasured confounding, acknowledge the limitations of observational studies and conducted a number of sensitivity analyses to mitigate these concerns.
    keywords: covid-19; mortality; patients; studies; study; tocilizumab
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        item: #2129 of 7819
          id: cord-276720-cltnk0rg
      author: Montrone, Michele
       title: Favourable outcome of COVID-19 in an ALK-positive NSCLC patient receiving Alectinib
        date: 2020-08-11
       words: 1158
      flesch: 40
     summary: The number of lung cancer patients with SARS-CoV-2 infection could be underestimated since the test is not routinely done in all symptomatic patients and the number of tests performed is not homogeneous even within a single nation like Italy, as reported by Carbone and Coll 4 ; therefore a large group of lung cancer patient may be positive but not recognized as such. However, few cases of COVID-19 in lung cancer patients have been reported to date.
    keywords: cancer; covid-19; lung
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        item: #2130 of 7819
          id: cord-276769-th7iou21
      author: Khan, Suliman
       title: Coronaviruses disease 2019 (COVID-19): causative agent, mental health concerns, and potential management options
        date: 2020-07-25
       words: 3381
      flesch: 40
     summary: In this paper, we discuss the transmission, health consequences, and potential management (therapeutic and preventive) options for COVID-19 disease. In this article, we briefly describe the consequences of highly infectous human corona viruses, and elaborate the transmission and health consequences (both physical and mental health) of COVID-19 disease.
    keywords: coronavirus; cov-2; covid-19; disease; health; sars; transmission
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        item: #2131 of 7819
          id: cord-276784-8lmg97zc
      author: Boziki, Marina Kleopatra
       title: COVID-19 Immunopathology and the Central Nervous System: Implication for Multiple Sclerosis and Other Autoimmune Diseases with Associated Demyelination
        date: 2020-06-04
       words: 4784
      flesch: 24
     summary: Tocilizumab as a Potential Therapy Against COVID-19 Tocilizumab for the management of immune mediated adverse events secondary to PD-1 blockade Multiple sclerosis and the risk of infection: Considerations in the threat of the novel coronavirus, COVID-19/SARS-CoV-2 Neuroinvasion by human respiratory coronaviruses Epidemiologic evidence for multiple sclerosis as an infection An Italian programme for COVID-19 infection in multiple sclerosis Viruses and endogenous retroviruses in multiple sclerosis: Although most of COVID-19 patients exhibit normal leukocyte count, leucopenia
    keywords: coronavirus; cov-2; covid-19; disease; immune; infection; patients; potential; sars; system
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        item: #2132 of 7819
          id: cord-276829-c1krlejx
      author: José Antonio, Soriano Sánchez
       title: EARLY REPORT ON THE IMPACT OF COVID-19 OUTBREAK IN NEUROSURGICAL PRACTICE AMONG MEMBERS OF THE LATIN AMERICAN FEDERATION OF NEUROSURGICAL SOCIETIES
        date: 2020-05-07
       words: 1605
      flesch: 42
     summary: Telemedicine represents an excellent solution, avoiding another pandemic of severe diseases across all-specialties as non-essential care can turn essential if left untreated. Suboptimal treatment can theoretically turn non-essential care pathologies into 231 essential care pathologies at an exponential growth rate, as massive or even more, than 232 COVID-19 Pandemic.
    keywords: care; covid-19; health; latin; neurosurgical
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        item: #2133 of 7819
          id: cord-276834-20lcihf4
      author: Idilman, Ilkay S.
       title: Lung and kidney perfusion deficits diagnosed by dual-energy computed tomography in patients with COVID-19-related systemic microangiopathy
        date: 2020-08-29
       words: 4517
      flesch: 43
     summary: KEY POINTS: • Pulmonary perfusion abnormalities in COVID-19 patients, associated with disease severity, can be detected by pulmonary DECT. However, these findings are based on recent pathological studies and it is evident that noninvasive diagnosis of the microvascular obstruction would be beneficial in the management of COVID-19 patients using early thromboprophylaxis.
    keywords: covid-19; dect; images; iodine; kidney; lung; patients; pds; perfusion; pulmonary
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        item: #2134 of 7819
          id: cord-276870-gxtvlji7
      author: Bobrowski, Tesia
       title: Learning from history: do not flatten the curve of antiviral research!
        date: 2020-07-15
       words: 5092
      flesch: 43
     summary: Additionally, modern computational techniques, such as quantitative structure-activity relationship (QSAR) modeling, molecular docking, and machine-learning approaches are being used now in COVID-19 drug discovery efforts [17, 40, 41] . HIVGov 30 AIDSinfo (2018) FDA-Approved HIV Medicines The application of structural optimization strategies in drug design of HIV NNRTIs EASY-HIT: HIV full-replication technology for broad discovery of multiple classes of HIV inhibitors Evaluating the Efficacy and Safety of Bromhexine Hydrochloride Tablets Combined With Standard Treatment/ Standard Treatment in Patients With Suspected and Mild Novel Coronavirus Pneumonia (COVID-19) COVID-19 Ring-based Prevention Trial With Lopinavir/Ritonavir Pre-exposure Prophylaxis for SARS-Coronavirus-2 HIV epidemiology and the effects of antiviral therapy on longterm consequences Viral evolution and the emergence of SARS coronavirus Immunity Passports' in the Context of COVID-19 Structure of Mpro from COVID-19 virus and discovery of its inhibitors Artificial intelligence and machine learning to fight COVID-19 Mapping the landscape of artificial intelligence applications against Improving Health and Reducing Poverty Trump disbanded NSC pandemic unit that experts had praised CDC to cut by 80 percent efforts to prevent global disease outbreak Tecovirimat for the Treatment of Smallpox Disease Antimicrobial Division Advisory Committee Meeting.
    keywords: covid-19; data; epidemics; hiv; number; publications; research; response; sars; time
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        item: #2135 of 7819
          id: cord-276879-u39a6nwc
      author: Crotty, Frances
       title: Nursing homes: the titanic of cruise ships – will residential aged care facilities survive the coronavirus disease 2019 pandemic?
        date: 2020-08-10
       words: 2481
      flesch: 49
     summary: However, there are no accurate data on the proportion of these that were RACF residents. There are concerns about the sector's ability to care for sick and dying residents, as highlighted by disturbing international reports of RACF residents being left abandoned or dead in facilities.
    keywords: care; covid-19; facilities; racf; residents
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        item: #2136 of 7819
          id: cord-276895-p85obwp2
      author: Carriazo, Sol
       title: Kidney disease and electrolytes in COVID-19: more than meets the eye
        date: 2020-07-16
       words: 3643
      flesch: 38
     summary: Hospitals were overwhelmed by COVID-19 patients and healthcare personnel were not provided with appropriate protective equipment, becoming one of the hardest hit communities ( Figure 3 ). Hyponatraemia is common in COVID-19 patients and the cause appears to be outside the kidneys, as occurrence of the syndrome of inappropriate antidiuretic hormone (SIADH) has been well characterized by Ravioli et al.
    keywords: acute; aki; coronavirus; cov-2; covid-19; disease; injury; kidney; patients; syndrome
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        item: #2137 of 7819
          id: cord-276908-9jthjf24
      author: Gupta, Akanksha
       title: COVID‐19: Emergence of Infectious Diseases, Nanotechnology Aspects, Challenges, and Future Perspectives
        date: 2020-07-06
       words: 5182
      flesch: 52
     summary: [92] Au NPs based materials are well known for the detection of various viruses such as dengue virus, influenza virus, bovine viral diarrhea coronavirus, etc. The viral infection encountered with present‐day challenges and futuristic approaches with the help of nanotechnology to minimize the spread of infectious viruses.
    keywords: antiviral; coronavirus; covid-19; covs; disease; drugs; hcov; host; human; infection; protein; rna; sars; virus; viruses
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        item: #2138 of 7819
          id: cord-276938-hv2ttwr8
      author: Artru, Florent
       title: Acute immune thrombocytopaenic purpura in a patient with COVID-19 and decompensated cirrhosis
        date: 2020-07-07
       words: 1319
      flesch: 43
     summary: Of note, this outcome is remarkable also in light of recent data indicating an increased mortality from COVID-19 in patients with pre-existing liver disease and, notably, cirrhosis. Immune thrombocytopenic purpura in a patient with Covid-19 Autoimmune and inflammatory diseases following COVID-19 COVID-19 and its implications for thrombosis and anticoagulation Immune thrombocytopenia COVID-19: consider cytokine storm syndromes and immunosuppression Clinical characteristics and outcomes of COVID-19 among patients with pre-existing liver disease in United States: a multi-center research network study Contributors FA and GS conceived the study, performed the literature research and wrote the paper.
    keywords: covid-19; patient; thrombocytopaenia
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        item: #2139 of 7819
          id: cord-276945-gly0stxm
      author: Coxon, Kirstie
       title: The impact of the Coronavirus (COVID-19) pandemic on maternity care in Europe
        date: 2020-06-10
       words: 3956
      flesch: 40
     summary: Differences emerge in how labour care and choice of place of birth has been planned, the reductions in antenatal and postnatal 'face to face' care provision and in promotion of skin to skin contact and breastfeeding for COVID-19 positive women following birth. In Spain, some hospitals have isolated COVID-19 positive women from their babies, with no skin to skin contact or breastfeeding until the mother tests negative, whilst others have kept COVID-19 positive and symptomatic women with their babies, encouraging usual skin to skin and breastfeeding care; in cases where symptomatic women have been separated because the woman's condition requires it, they have been supported to express breast milk or to breastfeed.
    keywords: birth; care; covid-19; face; midwives; staff; women
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        item: #2140 of 7819
          id: cord-276957-pk33dl8q
      author: Hu, Xuejiao
       title: Development and Clinical Application of a Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for SARS-CoV-2 Infection
        date: 2020-08-26
       words: 5659
      flesch: 39
     summary: RT-LAMP primers for COVID-19 were specific and had a 9.14% to 37.56% nucleotide mismatching with SARS, MERS, and other coronavirus sequences (see Table S2 ). Application of RT-LAMP for SARS-CoV-2 (ii) Cohort II.
    keywords: assay; cov-2; covid-19; detection; lamp; lamp assay; patients; qpcr; results; samples; sars
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        item: #2141 of 7819
          id: cord-276984-npgalqoz
      author: Dahl Mathiasen, Victor
       title: Uneventful case of COVID-19 in a kidney transplant recipient
        date: 2020-07-20
       words: 1783
      flesch: 46
     summary: COVID-19 Dashboard by the center for systems science and engineering A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia Successful recovery of COVID-19 pneumonia in a renal transplant recipient with long-term immunosuppression Covid-19 and kidney transplantation COVID-19 in solid organ transplant recipients: a single-center case series from Spain COVID-19 in kidney transplant recipients Outcomes from pandemic influenza A H1N1 infection in recipients of solid-organ transplants: a multicentre cohort study COVID-19: consider cytokine storm syndromes and immunosuppression Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Prevalence of obesity among adult inpatients with COVID-19 in France Managing COVID-19 in renal transplant recipients: a review of recent literature and case supporting Corticosteroid-sparing immunosuppression COVID-19 in solid organ transplant recipients: initial report from the US EpiCenter Acknowledgements We want to thank Professor Henrik Birn, MD, DMSc, PhD at The case demonstrates that kidney transplant recipients are not necessarily severely affected by COVID-19.
    keywords: case; covid-19; kidney; recipients; transplant
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        item: #2142 of 7819
          id: cord-277014-iz8jo44e
      author: Hu, Weihua
       title: Disorders of sodium balance and its clinical implications in COVID-19 patients: a multicenter retrospective study
        date: 2020-10-16
       words: 3650
      flesch: 39
     summary: In addition, hyponatremia patients required extensive treatment with oxygen, antibiotics, and corticosteroids. In addition, hyponatremia patients required intensive oxygen treatment compared to normonatremia patients (87.1 vs 60.1%) including the use of oxygen inhalation, oxygen absorption by mask, high-influx oxygen absorption, and non-invasive and invasive ventilation ( Table 3 ).
    keywords: clinical; covid-19; hyponatremia; normonatremia; patients; sodium; study; table; total
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        item: #2143 of 7819
          id: cord-277019-salizr5n
      author: Horowitz, James M.
       title: Clot in Transit on Transesophageal Echocardiography in a Prone Patient with COVID-19 Acute Respiratory Distress Syndrome
        date: 2020-05-16
       words: 1640
      flesch: 37
     summary: D-dimer rose to 4,070 mg/mL and the patient was transitioned to therapeutic LMWH at a dose of 1 mg/kg every 12 hours given the suspected increased risk of thrombosis among patients with COVID-19. Given rapid hemodynamic and respiratory decompensation with a significantly elevated Ddimer level, an emergent TEE (Philips Affinity, X7 probe) was performed to exclude proximal pulmonary embolism (PE), and to evaluate for alternative causes of deterioration while patient remained in prone position (Figure 2) .
    keywords: cit; covid-19; patients; pulmonary; tee
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        item: #2144 of 7819
          id: cord-277086-j7hih6o9
      author: Atchison, Christina J
       title: Perceptions and behavioural responses of the general public during the COVID-19 pandemic: A cross-sectional survey of UK Adults
        date: 2020-04-03
       words: 3878
      flesch: 45
     summary: Adoption of social distancing measures was proxied by respondents reporting to have avoided crowded places and social events to protect themselves or others from COVID- Variables that appeared to be associated (p<0.20) in the unadjusted analyses were considered in the adjusted analyses. This was particularly marked for social distancing measures (Figure 1 ).
    keywords: covid-19; home; isolate; measures; preprint; public; self
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        item: #2145 of 7819
          id: cord-277098-nxetsw13
      author: Naqos, N.
       title: The study of physical and mental distress among cancer patients during the COVID-19 epidemic
        date: 2020-09-30
       words: 1647
      flesch: 50
     summary: key: cord-277098-nxetsw13 authors: Naqos, N.; Khouchani, M. title: The study of physical and mental distress among cancer patients during the COVID-19 epidemic date: 2020-09-30 journal: Annals of Oncology DOI: 10.1016/j.annonc.2020.08.1838 sha: doc_id: 277098 cord_uid: nxetsw13 nan Background: On March 11, 2020, COVID-19 was declared a global pandemic. Conclusions: During the outbreak of COVID-19, the vast majority of cancer patients (more than half) in our study developed anxiety, depression and fear of COVID-19 infection.
    keywords: cancer; covid-19; pandemic; patients; pts
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        item: #2146 of 7819
          id: cord-277107-gs7j6fxo
      author: Yamin, Mohammad
       title: Counting the cost of COVID-19
        date: 2020-05-13
       words: 4181
      flesch: 61
     summary: But in many other developing countries there has been a virtual wash out of educational activities at all level since March 2020. Politicians in many countries have responded to salvage their economies.
    keywords: coronavirus; countries; covid-19; health; pandemic; people; spread; virus; world
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        item: #2147 of 7819
          id: cord-277110-e27lm7rr
      author: Iria, Neri
       title: Major cluster of pediatric “ true ” primary chilblains during the COVID‐19 pandemic: a consequence of lifestyle changes due to lockdown
        date: 2020-06-13
       words: 2907
      flesch: 47
     summary: We were not able to test other patients due to the difficulties to access the hospital. The observation of other cases, with a careful clinical examination and an accurate history will provide further diagnostic clues and will be necessary to verify our hypothesis.
    keywords: cases; chilblain; children; covid-19; infection; lesions; patients
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        item: #2148 of 7819
          id: cord-277117-11m27kmi
      author: Khialani, Bharat
       title: Transcatheter management of severe aortic stenosis during the COVID-19 pandemic
        date: 2020-06-10
       words: 4664
      flesch: 40
     summary: The need for permanent pacing Permanent pacemaker rates have also been higher in TAVI patients, particularly with the self-expanding valves. 25 Is it reasonable to convert patients selected for sAVr to TAVI: the current data for TAVI in low risk patients? Is 'diversion' of patients already accepted for sAVR to TAVI supported by the current evidence?
    keywords: aortic; covid-19; patients; replacement; risk; stenosis; tavi; transcatheter; treatment; valve
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        item: #2149 of 7819
          id: cord-277123-ekaqbruo
      author: Novosad, P.
       title: The COVID-19 mortality effects of underlying health conditions in India: a modelling study
        date: 2020-07-08
       words: 4727
      flesch: 43
     summary: Based on the availability of existing measures, our model assumed that health condition relative risks are age-invariant. Additional information on health condition prevalence on individuals aged 18 to 99 was obtained from the Health Survey for England and the Global Burden of Diseases, Risk Factors, and Injuries Studies (GBD).
    keywords: age; conditions; covid-19; england; health; india; mortality; risk
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        item: #2150 of 7819
          id: cord-277146-4a4vz36h
      author: Aggarwal, Mukul
       title: Hemostatic Abnormalities in COVID-19: An Update
        date: 2020-08-11
       words: 4633
      flesch: 37
     summary: Lupus anticoagulant is frequent in patients with Covid-19 High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Incidence of asymptomatic deep vein thrombosis in patients with COVID-19 pneumonia and elevated D-dimer levels High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Arterial thromboembolic complications in COVID-19 in low risk patients despite prophylaxis Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Direct oral anticoagulant plasma levels' striking increase in severe COVID-19 respiratory syndrome patients treated with antiviral agents: the Cremona experience Tissue plasminogen activator (tPA) treatment for COVID-19 associated acute respiratory distress syndrome (ARDS): a case series Therapeutic effects of dipyridamole on COVID-19 patients with coagulation dysfunction Eculizumab treatment in patients with COVID-19: preliminary results from real life ASL Napoli 2 The species severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 COVID-19: towards understanding of pathogenesis Clinical features of patients infected with 2019 novel coronavirus in Wuhan COVID-19: consider cytokine storm syndromes and immunosuppression Cytokine storm and sepsis disease pathogenesis The coagulopathy of acute sepsis Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Clinical characteristics of coronavirus disease 2019 in China Pulmonary pathology of early-phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer Post-mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases Pathological findings of COVID-19 associated with acute respiratory distress syndrome Autopsy findings and venous thromboembolism in patients with COVID-19: a prospective cohort study Vander Heide RS (2020) Pulmonary and cardiac pathology in Covid-19: the first autopsy series from New Orleans The role of cytokines including interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease Thrombocytopenia and its association with mortality in patients with COVID-19 Association between platelet parameters and mortality in coronavirus disease 2019: retrospective cohort study Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 PROTECT collaborators, the Canadian Critical Care Trials Group, and the Australian, and New Zealand Intensive Care Society Clinical Trials Group (2013) Thrombocytopenia in critically ill patients receiving thromboprophylaxis: frequency, risk factors, and outcomes Mechanism of thrombocytopenia in COVID-19 patients COVID-19-related severe hypercoagulability in patients admitted to intensive care unit for acute respiratory failure Incidence of venous thromboembolism in hospitalised patients with COVID-19 Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19 Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia D-dimer is associated with severity of coronavirus disease 2019: a pooled analysis The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome Hypercoagulability of COVID-19 patients in intensive care unit a report of thromboelastography findings and other parameters of hemostasis Prominent changes in blood coagulation of patients with SARS-CoV-2 infection Coagulopathy and antiphospholipid antibodies in patients with Covid-19 International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)
    keywords: coagulation; coagulopathy; covid-19; dimer; disease; mortality; patients; pulmonary; risk; thromboprophylaxis; thrombosis
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        item: #2151 of 7819
          id: cord-277178-nbotxv35
      author: Vindrola-Padros, C.
       title: Remote home monitoring (virtual wards) during the COVID-19 pandemic: a living systematic review
        date: 2020-10-09
       words: 5045
      flesch: 43
     summary: key: cord-277178-nbotxv35 authors: Vindrola-Padros, C.; Singh, K.; Sidhu, M. S.; Georghiou, T.; Sherlaw-Johnson, C.; Tomini, S. M.; Inada-Kim, M.; Kirkham, K.; Streetly, A.; Fulop, N. J. title: Remote home monitoring (virtual wards) during the COVID-19 pandemic: a living systematic review date: 2020-10-09 journal: nan DOI: 10.1101/2020.10.07.20208587 sha: doc_id: 277178 cord_uid: nbotxv35 Objectives: The aim of this review was to analyse the implementation and impact of remote home monitoring models (virtual wards) during COVID-19, identifying their main components, processes of implementation, target patient populations, impact on outcomes, costs and lessons learnt. Setting: The review included remote home monitoring models led by primary and secondary care across seven countries.
    keywords: articles; care; covid-19; home; models; monitoring; patient; preprint; review
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        item: #2152 of 7819
          id: cord-277188-t33nw4zb
      author: Fang, Jie
       title: Efficacy of Early Combination Therapy With Lianhuaqingwen and Arbidol in Moderate and Severe COVID-19 Patients: A Retrospective Cohort Study
        date: 2020-09-18
       words: 4643
      flesch: 43
     summary: Undoubtedly, great efforts have been made to identify effective medical products, such as drugs and vaccines, to diagnose and treat COVID-19 patients. One clinical study found that COVID-19 patients in the Arbidol group had a shorter duration of positivity on RNA tests than those in the lopinavir/ritonavir group (Zhu Z. et al., 2020) .
    keywords: arbidol; combination; covid-19; group; lhqw; patients; study; therapy; time; treatment
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        item: #2153 of 7819
          id: cord-277189-fe8ego7f
      author: Szabados, Bernadett
       title: Clinical Characteristics and Outcome for Four SARS-CoV-2-infected Cancer Patients Treated with Immune Checkpoint Inhibitors
        date: 2020-05-26
       words: 1705
      flesch: 49
     summary: Eur Urol DOI: 10.1016/j.eururo.2020.05.024 sha: doc_id: 277189 cord_uid: fe8ego7f Preliminary data suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with higher mortality among cancer patients, particularly in those on systemic therapy. Preliminary data suggest that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease 2019 ) is associated with higher mortality among cancer patients [1] .
    keywords: cancer; covid-19; patients; treatment
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        item: #2154 of 7819
          id: cord-277201-jzjxsetx
      author: Mazo, Jahinover
       title: More than Just Pneumonia: Acute Pulmonary Embolism in Two Middle-Aged Patients with COVID-19
        date: 2020-07-30
       words: 2652
      flesch: 40
     summary: Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China Early clinical and CT manifestations of coronavirus disease 2019 (COVID-19) pneumonia Acute pulmonary embolism associated with COVID-19 pneumonia detected by pulmonary CT Angiography Pulmonary embolism and increased levels of d-dimer in patients with coronavirus disease e emerging spectrum of cardiopulmonary pathology of the coronavirus disease 2019 (COVID-19): report of 3 autopsies from Houston, Texas, and review of autopsy findings from other United States cities Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Hypercoagulability of COVID-19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis Characteristics of ischaemic stroke associated with COVID-19 e use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): the perspectives of clinical immunologists from China romboinflammation and the hypercoagulability of COVID-19 e procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome Hyperinflammation and derangement of renin-angiotensinaldosterone system in COVID-19: a novel hypothesis for clinically suspected hypercoagulopathy and microvascular immunothrombosis Cytokines as Regulators of Coagulation Prevention, diagnosis, and treatment of VTE in patients with COVID-19 Predictive and associative models to identify hospitalized medical patients at risk for VTE Modified IM-PROVE VTE risk score and elevated D-dimer identify a high venous thromboembolism risk in acutely ill medical population for extended thromboprophylaxis A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score rombosis risk assessment as a guide to quality patient care romboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum Practical diagnosis and treatment of suspected venous thromboembolism during COVID-19 pandemic According to data from China, where the virus originated, 87% of COVID-19 patients were between the age 30-79 years
    keywords: covid-19; factors; patients; pulmonary; risk; thromboembolism; vte
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        item: #2155 of 7819
          id: cord-277203-14he8n3u
      author: Chen, Chang
       title: Favipiravir versus Arbidol for COVID-19: A Randomized Clinical Trial
        date: 2020-03-20
       words: 1275
      flesch: 49
     summary: Clinical recovery rate of Day 7 does not significantly differ between Favipiravir group (71/116) and Arbidol group (62/120) (P=0.1396, difference of recovery rate: 0.0954; 95% CI: -0.0305 to 0.2213). The primary outcome was clinical recovery rate of Day 7.
    keywords: group; medrxiv; patients; preprint
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        item: #2156 of 7819
          id: cord-277210-xaj2623u
      author: Weinkove, Robert
       title: Managing haematology and oncology patients during the COVID‐19 pandemic: interim consensus guidance
        date: 2020-05-13
       words: 6047
      flesch: 32
     summary: 10 Atypical clinical presentations of other infections are common among cancer patients receiving highly immunosuppressive therapies, 13 although whether this applies to COVID- 19 is not yet known. This may be of particular relevance to patients with lung cancer, who made up the majority of cancer patients affected by COVID-19 in an early report.
    keywords: cancer; care; cell; clinicians; cov-2; covid-19; guidance; health; infection; pandemic; patients; risk; sars; transfusion; treatment
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        item: #2157 of 7819
          id: cord-277228-zk4arqw5
      author: Suleiman, Aiman
       title: Preparedness of Frontline Doctors in Jordan Healthcare Facilities to COVID-19 Outbreak
        date: 2020-05-02
       words: 3554
      flesch: 45
     summary: Our questionnaire was designed to evaluate awareness and readiness of frontline doctors to deal with COVID-19 patients. Adding to availability of equipment, the preparedness of frontline doctors to the impact of the outbreak is what guarantees the system to function properly and efficiently.
    keywords: covid-19; doctors; healthcare; knowledge; patients; preparedness; score
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        item: #2158 of 7819
          id: cord-277237-tjsw205c
      author: Hernandez Vargas, Esteban Abelardo
       title: In-host Modelling of COVID-19 Kinetics in Humans
        date: 2020-03-30
       words: 3610
      flesch: 53
     summary: A quantitative comprehension of COVID-19 dynamics and the estimation of standard parameters of viral infections is the key contribution of this pioneering work. For parameter fitting purposes, we explore three different scenarios of initial infection day 96 (t i ), that is, -14, -7, -3 days before the onset of symptoms for patients A and B, see Fig. 3 . .
    keywords: covid-19; host; infection; license; medrxiv; model; preprint; virus
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        item: #2159 of 7819
          id: cord-277248-7qnymo98
      author: dos Reis, Helena Lucia Barroso
       title: Severe coronavirus infection in pregnancy: challenging cases report
        date: 2020-07-13
       words: 2812
      flesch: 44
     summary: This study reports three cases of COVID-19 comprising pregnant women with severe respiratory failure and evaluates the clinical management of COVID-19 infection in obstetric clinics in Vitoria, Espirito Santo State, Brazil. A novel coronavirus from patients with pneumonia in China Expert consensus for managing pregnant women and neonates born to mothers with suspected or confirmed novel coronavirus (COVID-19) infection Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Pregnant women with new coronavirus infection: a clinical characteristics and placental pathological analysis of three cases Maternal deaths with coronavirus disease 2019: a different outcome from lowto middle-resource countries? Serial interval of COVID-19 among publicly reported confirmed cases COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of New York City hospitals An analysis of 38 Pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infections and pregnancy outcomes Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia A case report of neonatal COVID-19 infection in China Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn Diagnosis and treatment of 2019 novel coronavirus infection in children: a pressing issue Chloroquine and hydroxychloroquine during pregnancy: what do we know?
    keywords: cases; covid-19; day; days; infection; women
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        item: #2160 of 7819
          id: cord-277252-yw5wcq1e
      author: Belen-Apak, F. Burcu
       title: Pulmonary intravascular coagulation in COVID-19: possible pathogenesis and recommendations on anticoagulant/thrombolytic therapy
        date: 2020-05-05
       words: 670
      flesch: 31
     summary: Plasminogen and TPA has been used in COVID-19 patients in a few studies and have been shown to be beneficial in improving respiratory capacity According to the previous literature, we think the major pathogenesis of COVID-19 disease starts with hyper coagulation and PIC.
    keywords: covid-19; patients; treatment
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        item: #2161 of 7819
          id: cord-277260-7se220oz
      author: Gosain, Rohit
       title: COVID-19 and Cancer: a Comprehensive Review
        date: 2020-05-08
       words: 5943
      flesch: 35
     summary: However, in cancer patients on active treatment or even during watchful observation, lymphopenia (an independent poor prognostic indicator in COVID-19 patients) Emerging data highlighting concerns of coagulopathy in COVID-19 patients is becoming available, but it is too early to infer if these are more or less common in cancer patients [77] .
    keywords: cancer; china; coronavirus; cov-2; covid-19; disease; infection; pandemic; patients; risk; sars; syndrome; therapy; treatment; trials; use
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        item: #2162 of 7819
          id: cord-277313-5f5lrn3c
      author: Hayakawa, Satoshi
       title: Covid‐19 pandemic and pregnancy
        date: 2020-08-10
       words: 4627
      flesch: 46
     summary: Available from URL Focus on receptors for coronaviruses with special reference to angiotensin-converting enzyme 2 as a potential drug target-a perspective Origins of major human infectious diseases Phylogenetic network analysis of SARS-CoV-2 genomes On the origin and continuing evolution of SARS-CoV-2 Spread of SARS-CoV-2 in the Icelandic population SARS-CoV-2 productively infects human gut enterocytes Targeting SARS-CoV-2 Receptors as a means for reducing infectivity and improving antiviral and immune response: An algorithm-based method for overcoming resistance to antiviral agents Risk factors for mortality in 244 older adults with COVID-19 in Wuhan, China: A retrospective study The pathogenesis and treatment of the 'cytokine Storm' in COVID-19 Back to the future: Lessons learned from the 1918 influenza pandemic Gross examination report of a COVID-19 death autopsy Coagulopathy in COVID-19 Endothelial cell infection and endotheliitis in COVID-19 The unique immunological and microbial aspects of pregnancy Type 1 interferons as a potential treatment against COVID-19 Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: A retrospective review of medical records Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China Antibodies in infants born to mothers with COVID-19 pneumonia Coronavirus disease 2019 (COVID-19) in pregnant women: A report based on 116 cases Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies Executive management summary and short report of outcome Severe COVID-19 during pregnancy and possible vertical transmission Mortality of a pregnant patient diagnosed with COVID-19: A case report with clinical, radiological, and histopathological findings COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of new York City hospitals Pregnancy and perinatal outcomes of women with coronavirus disease (COVID-19) pneumonia: A preliminary analysis Maternal death due to COVID-19 disease Clinical course of severe and critical COVID-19 in hospitalized pregnancies: A US cohort study Second-trimester miscarriage in a pregnant woman with SARS-CoV-2 infection SARS-CoV-2 infection of the placenta Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn What are the risks of COVID-19 infection in pregnant women? Viral infections during pregnancy First antibody surveys draw fire for quality, bias Current laboratory diagnostics of coronavirus disease 2019 (COVID-19) However, in an Italian study, among 42 deliveries, 24 (57%) women delivered vaginally, with three cases undergoing induction of labor for obstetric reasons, while elective cesarean section was performed in 18 (43%) cases: in 8 cases, the indication was unrelated to COVID-19 infection, but in 10 cases, the indications were worsening dyspnea or other COVID-19-related symptoms.
    keywords: cases; china; coronavirus; covid-19; disease; infection; patients; pregnancy; sars; transmission; women
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        item: #2163 of 7819
          id: cord-277315-e26oc883
      author: Dhiman, Sapna
       title: Impact of COVID-19 outbreak on mental health and perceived strain among caregivers tending children with special needs
        date: 2020-10-06
       words: 5562
      flesch: 43
     summary: A significant difference in caregiver strain (p < 0.001, effect size = 0.93) was observed during the outbreak compared to levels pre-outbreak (pre-outbreak strain was measured retrospectively). To observe the impact of the COVID-19 outbreak on caregiver strain, participants were asked to retrospectively note the strain they perceived one month before the pandemic.
    keywords: anxiety; caregivers; children; covid-19; depression; health; outbreak; rehabilitation; strain; stress; symptoms
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        item: #2164 of 7819
          id: cord-277328-9s8fwg1h
      author: Zhuang, Yuandi
       title: Dynamic changes on chest CT of COVID-19 patients with solitary pulmonary lesion in initial CT
        date: 2020-09-04
       words: 3927
      flesch: 54
     summary: key: cord-277328-9s8fwg1h authors: Zhuang, Yuandi; Lin, Liaoyi; Xu, Xunhua; Xia, Tianyi; Yu, Huili; Fu, Gangze; Yang, Yunjun; Wang, Meihao; Sun, Houzhang title: Dynamic changes on chest CT of COVID-19 patients with solitary pulmonary lesion in initial CT date: 2020-09-04 journal: a At the first chest CT scan (day 1), a ground-glass lesion with partial consolidation was shown in the subpleural area of the right lower lobe; b at peak time (day 10), the lesion in the right lower lobe expanded with interlobular septal thickening and consolidation, and new lesions appeared in the upper lobes; c before discharge (day 17), the lesions were gradually absorbed and linear opacities were observed in the bilateral upper lobes; d after discharge (day 51), chest CT scan showed few GGO in the right lung, and the consolidation and linear opacities disappeared Fig.
    keywords: chest; covid-19; discharge; patients; score; time
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        item: #2165 of 7819
          id: cord-277343-0el69uxr
      author: Berkhout, Suze G.
       title: Identity, politics, and the pandemic: Why is COVID-19 a disaster for feminism(s)?
        date: 2020-10-13
       words: 1876
      flesch: 33
     summary: Sustainability: Science, Practice and Policy Disability, disablism, and COVID-19 pandemic triage Standing in the intersection: feminist voices, feminist practices in Communication Studies Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Many westernized health care systems have emphasized acute services while deprioritizing community care.
    keywords: care; covid-19; gender; health; pandemic; women
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        item: #2166 of 7819
          id: cord-277347-5innqoip
      author: Huang, Y.
       title: A cohort study of 223 patients explores the clinical risk factors for the severity diagnosis of COVID-19
        date: 2020-04-24
       words: 2950
      flesch: 53
     summary: Of the risk factors evaluated, we found the levels of D-dimer, CRP, LDH, and PCT are significantly higher in severe patients than in non-severe patients (Figure3) . Moreover, we tracked dynamic changes during the process of COVID-19, and found CRP, D-dimer, LDH, PCT kept in high levels in severe patient.
    keywords: clinical; covid-19; dimer; factors; patients; study
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        item: #2167 of 7819
          id: cord-277350-zwu254n6
      author: Bianco, F.
       title: Preventing transmission among operating room staff during COVID-19 pandemic: the role of the Aerosol Box and other personal protective equipment
        date: 2020-05-24
       words: 1546
      flesch: 40
     summary: Considering the high risk of disease transmission during AGMP, we support the use of both PPE and AB to protect surgical staff during the current COVID-19 outbreak. Considerations of surgeons working in an Italian COVID-19 red zone Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese center for disease control and prevention cal-manag ement -of-sever e-acute -respi rator y-infec tion-when-novel -coron aviru s-(ncov)-infec tion-is-suspe cted Global guidance for surgical care during the COVID-19 pandemic Barrier enclosure during endotracheal intubation Acute intestinal ischaemia in a patient with COVID-19.
    keywords: aerosol; covid-19; pandemic; patients; staff
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        item: #2168 of 7819
          id: cord-277356-tay0kfyj
      author: Patel, Rusha J.
       title: Early institutional head and neck oncologic and microvascular surgery practice patterns across the United States during the SARS‐CoV‐2 (COVID19) pandemic
        date: 2020-04-28
       words: 2296
      flesch: 43
     summary: Here is presented the data from 14 different institutions, focusing specifically on early practice patterns related to head and neck surgery and patient care. As a subspecialty, head and neck cancer surgeons have had to balance infection risk with patient care.
    keywords: cancer; care; covid-19; head; institutions; neck
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        item: #2169 of 7819
          id: cord-277357-lpurk7pe
      author: González-González, Everardo
       title: Portable and accurate diagnostics for COVID-19: Combined use of the miniPCR thermocycler and a well-plate reader for SARS-CoV-2 virus detection
        date: 2020-08-13
       words: 4008
      flesch: 44
     summary: The blueGel1 has several important advantages and represents a valid and portable solution for detecting PCR amplification products. Our results suggest that using a commercial plate reader to determine the extent of advance of PCR amplifications is a practical, reliable, reproducible, and robust alternative to the use of gel electrophoresis.
    keywords: amplification; cov-2; covid-19; detection; fluorescence; minipcr; plate; reader; sars
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        item: #2170 of 7819
          id: cord-277405-5l7wsreg
      author: Andany, Nisha
       title: Home or Cabin: Community Care for Coronavirus Disease 2019
        date: 2020-09-03
       words: 1370
      flesch: 38
     summary: One major potential advantage of mobile cabin management over remote virtual care is intensive clinical monitoring. However, the incremental labor and costs associated with mobile cabin hospitals could be worthwhile if they can (1) provide safer oversight of at-risk patients and/or (2) decrease community transmission of COVID-19.
    keywords: cabin; care; covid-19; patients
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        item: #2171 of 7819
          id: cord-277416-agnpksxn
      author: Lu, Xuefang
       title: High Resolution CT Imaging Dynamic Follow-Up Study of Novel Coronavirus Pneumonia
        date: 2020-05-04
       words: 3590
      flesch: 44
     summary: COVID-19 pneumonia patients usually have flu-like symptoms clinically. In this study, 262 (97.04%) COVID-19 pneumonia patients were first diagnosed with fever symptoms, showing that this symptom is of great significance in the clinical pre-test triage of this disease (13) , but it should be pointed out that all patients in this group were feverish.
    keywords: cases; covid-19; lesions; lung; patients; pneumonia; type
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        item: #2172 of 7819
          id: cord-277430-x02u7oh0
      author: Zhang, Hongyan
       title: Outcomes of novel coronavirus disease 2019 (COVID‐19) infection in 107 patients with cancer from Wuhan, China
        date: 2020-06-23
       words: 3188
      flesch: 38
     summary: French consensus on management of head and neck cancer surgery during COVID-19 pandemic A practical approach to the management of cancer patients during the novel coronavirus disease 2019 (COVID-19) pandemic: an international collaborative group Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Information for laboratories about coronavirus (COVID-19) key: cord-277430-x02u7oh0 authors: Zhang, Hongyan; Wang, Linwei; Chen, Yuanyuan; Wu, Qiuji; Chen, Gaili; Shen, Xiaokun; Wang, Qun; Yan, Youqin; Yu, Yi; Zhong, Yahua; Wang, Xinghuan; Chua, Melvin L. K.; Xie, Conghua title: Outcomes of novel coronavirus disease 2019 (COVID‐19) infection in 107 patients with cancer from Wuhan, China date: 2020-06-23 journal: Cancer DOI: 10.1002/cncr.33042 sha: doc_id: 277430 cord_uid: x02u7oh0 BACKGROUND: Patients with cancer have a higher risk of coronavirus disease 2019 (COVID‐19) than noncancer patients.
    keywords: anticancer; cancer; covid-19; patients; study; treatment; wuhan
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        item: #2173 of 7819
          id: cord-277489-lsrqko6p
      author: Lai, Chih-Cheng
       title: Global epidemiology of coronavirus disease 2019 (COVID-19): disease incidence, daily cumulative index, mortality, and their association with country healthcare resources and economic status
        date: 2020-03-19
       words: 2131
      flesch: 57
     summary: To date, five regions have observed COVID-19 cases, including Asia, Eastern Mediterranean region, Europe, America and Africa. In the other 47 countries, the incidence of COVID-19 cases was < 2 per 1 0 0 0 0 0 0 population.
    keywords: cases; china; countries; covid-19
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        item: #2174 of 7819
          id: cord-277528-t0tglg0a
      author: Tay, Yi Xiang
       title: Clinical placements for undergraduate diagnostic radiography students amidst the COVID-19 pandemic in Singapore: Preparation, challenges and strategies for safe resumption
        date: 2020-08-18
       words: 3255
      flesch: 42
     summary: SIT prepared students by emphasising compliance to all risk measures, addressing concerns of risk transmission, meeting learning objectives, and reassessing infection control competencies. In tandem, SGH prepared an orientation program and used technology for open communication among faculty, clinical educators and students which included monitoring of well-being and rapid dissemination of updates.
    keywords: covid-19; education; learning; measures; placements; risk; sit; students
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        item: #2175 of 7819
          id: cord-277529-z2r14w2k
      author: Stella, Alessandro
       title: Familial Mediterranean Fever and COVID-19: Friends or Foes?
        date: 2020-09-18
       words: 3643
      flesch: 31
     summary: The pyrin inflammasome in health and disease Lack of clear and univocal genotype-phenotype correlation in familial Mediterranean fever patients: a systematic review The population genetics of familial mediterranean fever: a meta-analysis study MEFV mutations and their relation to major clinical symptoms of Familial Mediterranean Fever A novel cluster of patients with familial Mediterranean Fever (FMF) in southern Italy Genetic epidemiology of familial Mediterranean fever through integrative analysis of whole genome and exome sequences from Middle East and North Africa Global epidemiology of Familial Mediterranean fever mutations using population exome sequences A population genetics study of the familial Mediterranean fever gene: evidence of balancing selection under an overdominance regime NLRP3-associated autoinflammatory diseases: phenotypic and molecular characteristics of germline versus somatic mutations Phenotypic and genotypic characteristics of cryopyrinassociated periodic syndrome: a series of 136 patients from the Eurofever Registry Lessons Learned to Date on COVID-19 Hyperinflammatory Syndrome: considerations for Interventions to Mitigate SARS-CoV-2 Viral Infection and Detrimental Hyperinflammation Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC SARS-CoV-2 and ORF3a: nonsynonymous Mutations, Functional Domains, and Viral Pathogenesis. In addition, colchicine and IL-1 inhibitors treatments that are effective in controlling inflammation in FMF patients have recently been proposed for off-label use in COVID-19 patients.
    keywords: covid-19; fever; fmf; mediterranean; mefv; nlrp3; patients; pyrin; sars
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        item: #2176 of 7819
          id: cord-277539-xt2nt11e
      author: Kochhar, Anuraj Singh
       title: Dentistry during and after COVID-19 Pandemic: Pediatric Considerations
        date: 2020
       words: 4508
      flesch: 41
     summary: It is highly likely that dental professionals in upcoming days will come across COVID-19 patients and SARS-CoV-2 carriers, and hence must ensure a tactful handling of such patients to prevent its nosocomial spread. It is speculated that dental professionals will come across COVID-19 patients and SARS-CoV-2 carriers, and hence must ensure a careful handling of such patients to prevent its nosocomial spread.
    keywords: coronavirus; cov-2; covid-19; disease; infection; pandemic; patients; practice; sars; transmission; use
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        item: #2177 of 7819
          id: cord-277548-hgmmtew3
      author: Lou, Emil
       title: Perspectives of cancer patients and their health during the COVID-19 pandemic
        date: 2020-10-30
       words: 2841
      flesch: 42
     summary: The objective of this study was to compare concerns about COVID-19 among individuals undergoing cancer treatment to those with a history of cancer not currently receiving therapy and to those without a cancer history. Survey items included demographics, personal concerns about COVID-19, and among those currently receiving cancer therapy, perceived effects of the COVID-19 pandemic on cancer treatment.
    keywords: cancer; covid-19; history; pandemic; patients; treatment
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        item: #2178 of 7819
          id: cord-277564-x5qfxag3
      author: Kim, Si-Hyun
       title: Infection prevention and control practices for emergency surgery during the COVID-19 pandemic in a tertiary care hospital in South Korea
        date: 2020-10-24
       words: 1313
      flesch: 40
     summary: Guidelines for Surgery of Confirmed or Suspected COVID-19 Patients Preparedness for COVID-19 infection prevention in Korea: a single-centre experience In accordance with the Declaration of Helsinki 2013, all research involving human participants has to be registered in a publicly accessible database. Patients with findings suggestive of COVID-19 should be placed in a negative-pressure isolation room in the ED until the results of the rRT-PCR test for SARS-CoV-2 are confirmed as negative.
    keywords: covid-19; patients; risk; surgery
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        item: #2179 of 7819
          id: cord-277567-nf6t4ni6
      author: Bakkar, Sohail
       title: Impact of COVID-19 on thyroid cancer surgery and adjunct therapy
        date: 2020-06-14
       words: 1843
      flesch: 43
     summary: The aim of this retrospective cohort study was to assess the impact of the restrictive healthcare measures applied in the kingdom of Jordan in the time of COVID-19 on treatment plans for thyroid cancer patients. In a region of no or low COVID-19 prevalence, restrictive policies applied did not affect the safe and timely delivery of surgical care for thyroid cancer patients.
    keywords: care; covid-19; patients; ria
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        item: #2180 of 7819
          id: cord-277568-eqgxk63s
      author: Sory, Barry Ibrahima
       title: Impact de la pandémie de COVID-19 sur les activités du service de cardiologie de l’hôpital national
        date: 2020-10-01
       words: 1981
      flesch: 47
     summary: Nous avons recensé la fréquence des consultations et des hospitalisations du mois de Mars au mois d’Avril 2020, que nous avons comparé à la fréquence des consultations et des hospitalisation des mois de Janvier et Février 2020. Nous avons recensé la fréquence des consultations et des hospitalisations du mois de Mars au mois d'Avril 2020, que nous avons comparé à la fréquence des consultations et des hospitalisation des mois de Janvier et Février 2020.
    keywords: covid-19; des; les; patients
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        item: #2181 of 7819
          id: cord-277576-3dvt6uj7
      author: Demir, Erol
       title: COVID‐19 in kidney transplant recipients: A multicenter experience in Istanbul
        date: 2020-07-13
       words: 2243
      flesch: 47
     summary: However, it is unclear which markers are useful for the monitoring of kidney transplant recipient patients. 8, 9 Acute kidney injury is also associated with increased morbidity and mortality in COVID-19 patients.
    keywords: covid-19; kidney; patients; pneumonia; recipients; study; transplant
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        item: #2182 of 7819
          id: cord-277603-hpn1ovgo
      author: Strapazzon, Giacomo
       title: To compare the incomparable: COVID-19 pneumonia and high-altitude disease
        date: 2020-06-25
       words: 1056
      flesch: 30
     summary: In contrast to classic ARDS, lung volume and dead space in COVID-19 patients are often normal, consolidations absent and pulmonary and chest wall elastance preserved, but a severe capillary leak dominates the initial phase. [1] may rely on the initial clinical presentation of COVID-19 patients, showing profound hypoxaemia with no respiratory distress, similar to patients with acute high-altitude disease that have a chemoreceptor dysfunction.
    keywords: covid-19; patients; pneumonia
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        item: #2183 of 7819
          id: cord-277643-xh8z9v0m
      author: Khatiwada, Asmita Priyadarshini
       title: Paradigm shift of drug information centers during the COVID-19 pandemic
        date: 2020-07-20
       words: 3933
      flesch: 32
     summary: DICs can also greatly aid HCPs by providing current, complete, and accurate information on drug therapy and management approaches for treating COVID-19 patients with various comorbid conditions based on the scientific literature, and national and international guidelines. Given data from ongoing trials and emerging studies suggesting that hydroxychloroquine and chloroquine do not help to decrease the mortality or speed the recovery of COVID-19 patients, and the potential for life-threatening heart rhythm problems, the FDA withdrew the EUA for their use in COVID-19 [38] .
    keywords: covid-19; dics; disease; drug; hcps; health; information; patients; pharmacists
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        item: #2184 of 7819
          id: cord-277646-l956pxe5
      author: Münch, Urs
       title: Empfehlungen zur Unterstützung von belasteten, schwerstkranken, sterbenden und trauernden Menschen in der Corona-Pandemie aus palliativmedizinischer Perspektive: Empfehlungen der Deutschen Gesellschaft für Palliativmedizin (DGP), der Deutschen Interdisziplinären Vereinigung für Intensiv- und Notfallmedizin (DIVI), des Bundesverbands Trauerbegleitung (BVT), der Arbeitsgemeinschaft für Psychoonkologie in der Deutschen Krebsgesellschaft, der Deutschen Vereinigung für Soziale Arbeit im Gesundheitswesen (DVSG) und der Deutschen Gesellschaft für Systemische Therapie, Beratung und Familientherapie (DGSF)
        date: 2020-06-02
       words: 1653
      flesch: 26
     summary: Klinische Psychosoziale Notfallversorgung -Handlungsempfehlungen Five essential elements of immediate and mid-term mass trauma intervention: empirical evidence Palliativpsychologie -Berufsbild für Psychologinnen und Psychologen in der Palliativversorgung Konzept Spirituelle Begleitung in der Palliativmedizin der Sektion Seelsorge der DGP Profil Soziale Arbeit in Palliative Care der Sektion Soziale Arbeit der DGP Allgemein Deutsche key: cord-277646-l956pxe5 authors: Münch, Urs; Müller, Heidi; Deffner, Teresa; von Schmude, Andrea; Kern, Martina; Kiepke-Ziemes, Susanne; Radbruch, Lukas title: Empfehlungen zur Unterstützung von belasteten, schwerstkranken, sterbenden und trauernden Menschen in der Corona-Pandemie aus palliativmedizinischer Perspektive: Empfehlungen der Deutschen Gesellschaft für Palliativmedizin (DGP), der Deutschen Interdisziplinären Vereinigung für Intensiv- und Notfallmedizin (DIVI), des Bundesverbands Trauerbegleitung (BVT), der Arbeitsgemeinschaft für Psychoonkologie in der Deutschen Krebsgesellschaft, der Deutschen Vereinigung für
    keywords: auch; corona; covid-19; der; deutschen; die; empfehlungen; für; mit; pandemie; patient*innen; patients; und; von
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        item: #2185 of 7819
          id: cord-277648-9kxwkcbl
      author: Overholt, Kalon J.
       title: Dissecting the common and compartment-specific features of COVID-19 severity in the lung and periphery with single-cell resolution
        date: 2020-06-19
       words: 10011
      flesch: 34
     summary: Notably, the concerted TNF-α/NF-κB pathway enrichment across BALF cell types is indicative of a strong upregulation of TNFAIP3 and NFKBIA. Exploring the expression of these 16 ligands across the diversity of BALF cell types indicates that MPs and neutrophils may act as sender cells signaling to the epithelium, as suggested in recent reports [21, 28, 53] .
    keywords: analysis; ards; balf; cell; control; covid-19; disease; donors; expression; figure; gene; ligands; lung; patients; severity; type
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        item: #2186 of 7819
          id: cord-277669-uujny2dm
      author: Lumpuy-Castillo, Jairo
       title: Cardiovascular Damage in COVID-19: Therapeutic Approaches Targeting the Renin-Angiotensin-Aldosterone System
        date: 2020-09-04
       words: 7451
      flesch: 32
     summary: The Science Underlying COVID-19: Implications for the Cardiovascular System SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues A Suspicious Role of Interferon in the Pathogenesis of SARS-CoV-2 by Enhancing Expression of ACE2 Structural Variations in Human ACE2 May Influence Its Binding With SARS-CoV-2 Spike Protein ACE2 Receptor Polymorphism: Susceptibility to SARS-CoV-2, Hypertension, Multi-Organ Failure, and COVID-19 Disease Outcome ACE2 Gene Variants May Underlie Interindividual Variability and Susceptibility to COVID-19 in the Italian Population The Expression and Polymorphism of Entry Machinery for COVID-19 in Human: Juxtaposing Population Groups, Gender, and Different Tissues Molecular Simulation of SARS-CoV-2 Spike Protein Binding to Pangolin ACE2 or Human ACE2 Natural Variants Reveals Altered Susceptibility to Infection Human ACE2 Receptor Polymorphisms Predict SARS-CoV-2 Susceptibility. In addition, the presence of ACE2 receptors on the myocardium provides a theoretical mechanism for direct SARS-CoV-2 infection [23, 54] (Figure 1 ).
    keywords: ace2; ang-(1; angiotensin; cells; cov-2; covid-19; disease; endothelial; hypertension; infection; patients; receptor; sars; system
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        item: #2187 of 7819
          id: cord-277679-sc9hugxr
      author: Khateb, Mohamed
       title: Coronaviruses and Central Nervous System Manifestations
        date: 2020-06-23
       words: 4211
      flesch: 32
     summary: Similarly, the prevalence of psychiatric morbidity at 30 months after SARS infection was reported to reach up to one-third of the total survivors who presented with signs of various psychiatric diagnoses. In another case series of COVID-19 patients with AIS during their hospitalization (27) , all six had risk factors for stroke, and were detected with LVO.
    keywords: acute; cns; coronavirus; cov-2; covid-19; demyelination; human; infection; patients; sars; syndrome
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        item: #2188 of 7819
          id: cord-277693-6lrawta5
      author: Wang, Yuanzhuo
       title: Contributions of dermatologists to COVID‐19 research: a brief systematic review
        date: 2020-05-30
       words: 1408
      flesch: 35
     summary: 1, 2 Here, we systematically reviewed what dermatologists contributed to COVID-19 research. This study systematically reviewed contributions of dermatologists to COVID-19 research.
    keywords: articles; covid-19; dermatologists; dermatology
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        item: #2189 of 7819
          id: cord-277697-bdzx4hzk
      author: Pessaux, P.
       title: Réponse à « Stratégie pour la pratique de la chirurgie digestive oncologique en situation d’épidémie de COVID-19 »
        date: 2020-04-09
       words: 1094
      flesch: 52
     summary: Pour d'autre type de coronavirus, cela ne semble pas le cas avec 9 % (41/455) de pneumopathie à coronavirus pour les patients ayant un cancer et key: cord-277697-bdzx4hzk authors: Pessaux, P. title: Réponse à « Stratégie pour la pratique de la chirurgie digestive oncologique en situation d’épidémie de COVID-19 » date: 2020-04-09 journal:
    keywords: cancer; des; les; patients
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        item: #2190 of 7819
          id: cord-277698-g8sylrsj
      author: Chen, Dexiong
       title: Four cases from a family cluster were diagnosed as COVID‐19 after 14‐day of quarantine period
        date: 2020-04-08
       words: 490
      flesch: 50
     summary: However, Lauer et al 9 recently reported that 1% (101 out of every 10 000 cases) of suspected cases or close contacts would develop symptoms of COVID-19 after 14-day of quarantine period. Because only four cases were enrolled to estimate the incubation period in the present study, more cases should be in enrolled to further evaluate the incubation period of COVID-19 in the future.
    keywords: covid-19; period
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        item: #2191 of 7819
          id: cord-277700-nxm1jr0x
      author: Chassagnon, Guillaume
       title: AI-Driven CT-based quantification, staging and short-term outcome prediction of COVID-19 pneumonia
        date: 2020-04-22
       words: 4884
      flesch: 44
     summary: [22] [23] , which share common CT features with COVID-19 pneumonia, especially a predominance of ground glass opacities. Disease extent is the only parameter that can be visually estimated on chest CT to quantify disease severity 4, 5 , but visual quantification is difficult and usually coarse.
    keywords: chest; covid-19; disease; features; lung; network; patients; prognosis; segmentation; training
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        item: #2192 of 7819
          id: cord-277712-sx5k0m4q
      author: Hu, Ling-Qun
       title: COVID-19 and improved prevention of hospital-acquired infection
        date: 2020-05-31
       words: 788
      flesch: 44
     summary: Deaths Characteristics of COVID-19 infection in Beijing Figure 1: Comparison of distinguished mortalities over time between the continentals advocating Distancing & Handwashing vs Br J Anaesth DOI: 10.1016/j.bja.2020.05.037 sha: doc_id: 277712 cord_uid: sx5k0m4q nan protective equipment; social distancing Editor -Hospital-acquired infection rate is a hallmark metric for quality of care in US hospitals, where.7 million infections occurred while being treated for other ailments in 2018 (1) .
    keywords: covid-19; healthcare; hospital
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        item: #2193 of 7819
          id: cord-277717-q6jbu0r3
      author: Alonso, J.
       title: Mental Health Impact of the First Wave of COVID-19 Pandemic on Spanish Healthcare Workers: a Large Cross-sectional Survey
        date: 2020-10-30
       words: 5065
      flesch: 43
     summary: Being a physician and a nurse was consistently associated with significantly lower odds of current mental disorders, while being an auxiliary nurse with previous mental disorders showed high (but not significant) ORs of current disabling mental disorders. Here we report: current mental disorders (Major Depressive Disorder-MDD-
    keywords: covid-19; disorders; healthcare; lifetime; pandemic; preprint; prevalence; review; study; workers
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        item: #2194 of 7819
          id: cord-277739-eb4z3u66
      author: Hu, Ke
       title: Efficacy and Safety of Lianhuaqingwen Capsules, a repurposed Chinese Herb, in Patients with Coronavirus disease 2019: A multicenter, prospective, randomized controlled trial
        date: 2020-05-16
       words: 3673
      flesch: 41
     summary: To determine the safety and efficacy of LH capsule in patients with Covid-19. We did a prospective multicenter open-label randomized controlled trial on LH capsule in confirmed cases with Covid-19.
    keywords: capsules; covid-19; group; patients; rate; recovery; sars; study; treatment
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        item: #2195 of 7819
          id: cord-277755-wglxa801
      author: Dohlman, Jenny C.
       title: COVID-19 and Ophthalmologic Education: A Call to Innovate
        date: 2020-09-19
       words: 789
      flesch: 39
     summary: 3 Laboratory research, and thus resident and fellow research experience, have suffered as a result of nationwide closures of lab space and the halting of non-essential research activities. 2 Many are concerned about the effect that this shift has had on the education of the next generation of ophthalmologists, but in this moment, caring for COVID patients, preserving personal protective equipment, and protecting both our patients and ourselves, have taken priority.
    keywords: covid-19; ophthalmology; research
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        item: #2196 of 7819
          id: cord-277765-koa8ao10
      author: Stoddard, M.
       title: COVID-19 isolation and containment strategies for ships: Lessons from the USS Theodore Roosevelt outbreak
        date: 2020-11-07
       words: 4783
      flesch: 48
     summary: key: cord-277765-koa8ao10 authors: Stoddard, M.; Johnson, K.; White, D.; Nolan, R.; Hochberg, N.; Chakravarty, A. title: COVID-19 isolation and containment strategies for ships: Lessons from the USS Theodore Roosevelt outbreak date: 2020-11-07 journal: nan DOI: 10.1101/2020.11.05.20226712 sha: doc_id: 277765 cord_uid: koa8ao10 The control of shipborne disease outbreaks represents a vexing but entirely predictable challenge at the start of any pandemic. The challenge of managing shipborne disease outbreaks has been evident throughout history: the concept of quarantine itself dates back to restrictions placed on sailors in the era of the Black Death; in 1918, troopships were instrumental in spreading the influenza pandemic (Baraniuk, 2020); and in recent years, the cruise ship industry (COVID-19 pandemic on cruise ships, 2020; El Damanhoury and Cullinane, 2019; Hines, 2020) and the .
    keywords: crew; disease; evacuation; outbreak; rate; roosevelt; sailors; ship; testing
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        item: #2197 of 7819
          id: cord-277770-sbieo46s
      author: Oni, Tolu
       title: Implications of COVID-19 control measures for diet and physical activity, and lessons for addressing other pandemics facing rapidly urbanising countries
        date: 2020-09-01
       words: 2575
      flesch: 34
     summary: These restrictions have the potential to impact NCD risk factors such as dietary intake and physical activity behaviours [3] , by limiting access to healthy foods and to environments conducive to physical activity. The dynamics of purchasing and consumption of healthy food in this context, driven by limited access to fresh foods and refrigeration, has highlighted the growing wealth inequality within countries.
    keywords: access; activity; behaviours; covid-19; food; health; measures; pandemic
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        item: #2198 of 7819
          id: cord-277774-kec1o4ys
      author: Wang, Shangqian
       title: The need for urogenital tract monitoring in COVID-19
        date: 2020-04-20
       words: 1532
      flesch: 39
     summary: Patients with severe disease predominantly present with pneumonia-related symptoms. In December 2019, a series of patients with symptoms resembling viral pneumonia presented in Wuhan, Hubei province, China; however, the cause of this disease was unknown and it spread rapidly throughout China.
    keywords: cov-2; covid-19; patients; sars
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        item: #2199 of 7819
          id: cord-277788-6ls21tkr
      author: Nelson, Brian C
       title: Clinical Outcomes Associated with Methylprednisolone in Mechanically Ventilated Patients with COVID-19
        date: 2020-08-09
       words: 3556
      flesch: 45
     summary: On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine Clinical management of severe acute respiratory infection when COVID-19 is suspected Corticosteroids as adjunctive therapy in the treatment of influenza: an updated cochrane systematic review and meta-analysis Factors associated with psychosis among patients with severe acute Respiratory Syndrome: a case-control study Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome Effect of hypercortisone on development of shock among patients with severe sepsis Hydrocortisone therapy for patients with septic shock Early short course corticosteroids in hospitalized patients with COVID-19 Effect of systemic glucocorticoids on mortality or mechanical ventilation in patients with COVID-19 A c c e p t e d M a n u s c r i Clinical outcomes associated with the use of methylprednisolone were assessed in an unmatched, case-control study; a subset of patients also underwent propensity-score matching.
    keywords: corticosteroids; covid-19; days; methylprednisolone; patients; study
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        item: #2200 of 7819
          id: cord-277801-auq3msc6
      author: Deora, Harsh
       title: Adapting Neurosurgery Practice During The Covid-19 Pandemic In The Indian Subcontinent
        date: 2020-07-15
       words: 4982
      flesch: 47
     summary: While government institutions had an almost equitable distribution of the number of neurosurgeons between >10 and <10 groups (37 vs 44), private practice was dominated by teams comprising 2-5 neurosurgeons per team ( Figure 2D , Table 2 ). Hence, there was a need felt to understand the effect of the COVID epidemic on neurosurgical practice in the Indian subcontinent.
    keywords: covid; covid-19; media; neurosurgeons; pandemic; practice; public; respondents; survey
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        item: #2201 of 7819
          id: cord-277812-4cz2hziz
      author: Sieni, Elena
       title: Favourable outcome of coronavirus disease 2019 in a 1‐year‐old girl with acute myeloid leukaemia and severe treatment‐induced immunosuppression
        date: 2020-05-19
       words: 1349
      flesch: 39
     summary: Epidemiology of COVID-19 among children in China Flash survey on severe acute respiratory syndrome coronavirus-2 infections in paediatric patients on anticancer treatment COVID-19) -Infection Nevertheless, the management of COVID-19 in young patients with comorbidities, particularly cancer, remains a challenge for the clinician; further data are required to optimize the clinical approach to these cases.
    keywords: covid-19; day; disease; sars
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        item: #2202 of 7819
          id: cord-277816-ncdy9qgb
      author: Wang, Ji-gan
       title: Gastrointestinal symptoms and fecal nucleic acid testing of children with 2019 coronavirus disease: a systematic review and meta-analysis
        date: 2020-10-20
       words: 3604
      flesch: 39
     summary: Although gastrointestinal symptoms are often ignored, in children with diarrhea, abdominal pain, nausea, vomiting, and other gastrointestinal symptoms accompanied by a low fever, attention should be paid to their epidemiological history with screening of suspected patients. The positive rate of fecal nucleic acid testing in COVID-19 children was relatively high at 85.8% (91/106).
    keywords: children; coronavirus; cov-2; covid-19; nucleic; patients; sars; symptoms
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        item: #2203 of 7819
          id: cord-277833-x81ni7m5
      author: Stienen, Martin N.
       title: COVID-19 in Europe: Le roi est mort, vive le roi!
        date: 2020-05-18
       words: 1502
      flesch: 49
     summary: WHO Director-General's opening remarks at the media briefing on COVID-19 -13 World Health Organization UniversitätsSpital Zürich: 80 years of neurosurgical patient care in Switzerland COVID-19 and the role of spine surgeons. This is true for all aspects of life, but it is our responsibility to define standards in such situations for the field of spine surgery including patient care, education of students/residents/fellows and research.
    keywords: covid-19; europe; health; spine; world
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        item: #2204 of 7819
          id: cord-277841-7sp8ftbc
      author: Kumari, Pratibha
       title: Potential diagnostics and therapeutic approaches in COVID-19
        date: 2020-08-12
       words: 4881
      flesch: 40
     summary: While the level of E gene confirms the presence of SARS related virus. Like most immunological diagnostic protocols, Enzyme-Linked Immunosorbent Assay (ELISA) for COVID-19 detection uses IgM and IgG antibody against nucleocapsid (N) and receptor binding domain spike proteins (S) of SARS-CoV-2.
    keywords: clinical; coronavirus; cov-2; covid-19; detection; diagnosis; infection; novel; patients; rna; sars; test; treatment; virus
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        item: #2205 of 7819
          id: cord-277855-pfmslxy6
      author: Nunes Duarte‐Neto, Amaro
       title: Pulmonary and systemic involvement of COVID‐19 assessed by ultrasound‐guided minimally invasive autopsy
        date: 2020-05-22
       words: 2898
      flesch: 48
     summary: 16 MIA-US is a suitable alternative to conduct autopsies on COVID-19 cases because it considerably reduces its costs; the risk of producing aerosols is low and, therefore, it can be performed in services In H1N1pdm lungs extensive necrosis and haemorrhage were present, which are much less prominent or even absent in COVID-19 cases.
    keywords: autopsies; autopsy; cases; covid-19; disease; patients; study; tissue
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        item: #2206 of 7819
          id: cord-277862-yl7m77fo
      author: Li, M.
       title: Identifying novel factors associated with COVID-19 transmission and fatality using the machine learning approach
        date: 2020-06-12
       words: 3938
      flesch: 51
     summary: Among the four races, the White was a positive predictor of COVID-19 deaths, and the Asian and Arab were negative predictors of COVID-19 cases. The air passenger traffic and vehicle usage were a positive and a negative predictor of COVID-19 deaths, respectively, and the railway length was not selected by the Lasso for predicting COVID-19 cases, deaths, or CFRs.
    keywords: cases; cfrs; covid-19; deaths; preprint; risk
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        item: #2207 of 7819
          id: cord-277874-cr53ycrm
      author: Neault, N.
       title: SARS-CoV-2 Protein in Wastewater Mirrors COVID-19 Prevalence.
        date: 2020-09-03
       words: 7086
      flesch: 39
     summary: Ultimately, determining to what extent wastewater viral protein can serve as a prevalence leading indicator will require a longer study with more frequent sampling over rising and falling community prevalence in order to assess robustly. Moreover, the PEG precipitated influent solid viral RNA signal when detected did not correlate with viral RNA signal from PEG precipitated primary sludge, viral protein signal, or public health data (data not shown).
    keywords: cov-2; covid-19; influent; license; medrxiv; preprint; primary; protein; rna; samples; sars; signal; sludge; viral; wastewater
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        item: #2208 of 7819
          id: cord-277879-7ftu9b9q
      author: Martinez-Sanz, J.
       title: Effects of Tocilizumab on Mortality in Hospitalized Patients with COVID-19: A Multicenter Cohort Study
        date: 2020-06-09
       words: 4021
      flesch: 39
     summary: Tocilizumab targets the IL-6 receptor, and thus using baseline IL-6 levels instead of CRP in the interaction term with tocilizumab use could have helped to better discriminate the population benefiting most from tocilizumab treatment. 5 Tocilizumab is not currently approved for use by the FDA in COVID-19 patients.
    keywords: covid-19; crp; death; license; medrxiv; patients; preprint; tocilizumab
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        item: #2209 of 7819
          id: cord-277880-g0c6jchg
      author: Zhong, Jim
       title: The Impact of COVID-19 on Interventional Radiology Services in the UK
        date: 2020-11-03
       words: 3125
      flesch: 45
     summary: The study period for 2020 was selected to encompass the peak in COVID-19 cases throughout the UK and capture the subsequent effect on the provision of IR services. For the 2020 (COVID-19) group, we included COVID-19 status at the time of procedure which was split into three categories: confirmed COVID-19 case if polymerase chain reaction (PCR) test positive, suspected COVID-19 based on clinical or imaging evidence (even if PCR test negative) or not suspected with or without COVID-19 negative PCR test.
    keywords: acute; cases; covid-19; decrease; impact; study
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        item: #2210 of 7819
          id: cord-277889-8u685f45
      author: Costela-Ruiz, Víctor J.
       title: SARS-CoV-2 infection: the role of cytokines in COVID-19 disease
        date: 2020-06-02
       words: 9237
      flesch: 42
     summary: With respect to viral infections that target the respiratory system, Bot et al. observed that its expression during infection with an influenza virus had negative effects on CD8 + memory T cells [71] .Various studies of COVID-19 patients have detected elevated IL-4 levels as part of the cytokine storm associated with severe respiratory symptoms [16, 17, 43, 72] . f a subunit of the murine GM-CSF receptor A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the receptor for GM-CSF Molecular analysis of the granulocyte colony-stimulating factor receptor Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages Studies on the bone marrow colony stimulating factor (CSF): relation of tissue CSF to serum CSF IL-4, IL-5, and granulocyte/macrophage colony-stimulating factor, in allergen-induced late-phase cutaneous reactions in atopic subjects Pivotal roles of GM-CSF in autoimmunity and inflammation IP-10 in autoimmune thyroiditis TRAIL and IP-10 as biomarkers of viral infections in the emergency J o u r n a l P r e -p r o o f department Interferon gamma in autoimmunity: A complicated player on a complex stage MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile Monocyte chemoattractant protein-1 (MCP-1): an overview Hypothesis for potential pathogenesis of SARS-CoV-2 infection-a review of immune changes in patients with viral pneumonia Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients Targeting TNF and TNF Receptor Pathway in HIV-1 Infection: from Immune Activation to Viral Reservoirs COVID-19:
    keywords: cells; coronavirus; cov-2; covid-19; csf; cytokines; disease; factor; il-10; il-6; infection; levels; lung; patients; sars; study
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        item: #2211 of 7819
          id: cord-277916-b4yqek29
      author: Sridhar, Arun R.
       title: QT Interval and Arrhythmic Safety of Hydroxychloroquine Monotherapy in Coronavirus Disease 2019
        date: 2020-06-11
       words: 3608
      flesch: 39
     summary: In this multi-hospital retrospective cohort study of COVID-19 patients, HCQ monotherapy was not associated with malignant ventricular arrhythmias or arrhythmic cardiac arrest. In this retrospective, cohort study of COVID-19 patients treated with HCQ monotherapy, there were no instances of malignant ventricular arrhythmias or arrhythmic cardiac arrest.
    keywords: covid-19; hcq; msec; patients; prolongation; qtc; study
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        item: #2212 of 7819
          id: cord-277926-rt4ye7xt
      author: Haseeb, Sohaib
       title: Value of electrocardiography in coronavirus disease 2019 (COVID-19)
        date: 2020-08-06
       words: 2952
      flesch: 26
     summary: Cardiac arrhythmias have been reported in 16.7% of COVID-19 patients, while malignant arrhythmias have been reported in 11.5% of patients 1, 20 . Seek expert consultation if QTc remains ≥500 ms; -If QTc ≥470 ms for males or ≥480 ms for females by <500 ms, initiate antimicrobial drugs and consider repeat ECG in 48 hours; -In patients with clinically severe disease or taking multiple QT-prolonging medications, recheck QT after 48 hours of antimicrobial drug initiation; -If follow-up QTc increases ≥60 ms or is ≥500 ms, discontinue antimicrobial drugs and seek expert opinion Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19) Association of Cardiac Injury With Mortality in Hospitalized Patients With COVID-19 in Wuhan Potential Effects of Coronaviruses on the Cardiovascular System: A Review Characteristic Electrocardiographic Manifestations in Patients With COVID-19 COVID-19 with Different Severities: A Multicenter Study of Clinical Features Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis Clinical characteristics of non-critically ill patients with novel coronavirus infection (COVID-19) in a Fangcang Hospital Infection Unmasking Brugada Syndrome.
    keywords: cardiac; covid-19; disease; ecg; patients; prolongation
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        item: #2213 of 7819
          id: cord-277931-3hxhsmw8
      author: Khitan, Zeid J.
       title: SCan Charcoal Improve Outcomes in COVID-19 Infections?
        date: 2020-08-10
       words: 1090
      flesch: 23
     summary: Coronavirus infection in acute lower respiratory tract disease of infants Lifestyle risk factors, inflammatory mechanisms, and COVID-19 hospitalization: A community-based cohort study of 387,109 adults in UK Risk factors influencing the prognosis of elderly patients infected with COVID-19: a clinical retrospective study in Wuhan The COVID-19 Cytokine Storm; What We Know So Far Central Role for Adipocyte Na,K-ATPase Oxidant Amplification Loop in the Pathogenesis of Experimental Uremic Cardiomyopathy The Adipocyte Na/K-ATPase Oxidant Amplification Loop is the Central Regulator of Western Diet-Induced Obesity and Associated Comorbidities Oxidized HDL, Adipokines, and Endothelial Dysfunction: A Potential Biomarker Profile for Cardiovascular Risk in Women with Obesity pNaKtide inhibits Na/K-ATPase reactive oxygen species amplification and attenuates adipogenesis Uremic Toxins Activates Na/K-ATPase Oxidant Amplification Loop Causing Phenotypic Changes in Adipocytes in In Vitro Models Protein-bound uremic toxins, inflammation and oxidative stress: a cross-sectional study in stage 3-4 chronic kidney disease Altered microbiome in chronic kidney disease: systemic effects of gut-derived uremic toxins Oral activated charcoal adsorbent ameliorates chronic kidney disease-induced intestinal epithelial barrier disruption The Role of Adipocytes and Adipocyte-Like Cells in the Severity of COVID-19 Infections Relationship between changes in body fat and a decline of renal function in the elderly Enterovirus 71 3C Promotes Apoptosis through Cleavage of PinX1, a Telomere Binding Protein ACE2 is expressed in mouse adipocytes and regulated by a high-fat diet Relief of idiopathic generalized pruritus in dialysis patients treated with activated oral charcoal Oral activated charcoal in patients with uremic pruritus Use of activated charcoal for adsorption and elution of ribooligonucleotides Investigating the effect of carbon shape on virus adsorption Infection of bat and human intestinal organoids by SARS-CoV-2 This work was supported by National Institutes of Health grants HL109015, HL071556 and HL105649 (to JIS), HL55601 and HL34300 (to NGA), COBRE ACCORD grant (1P20GM121299) (US), and the BrickStreet Foundation and the Huntington Foundation, Inc. (to JIS). We propose to examine the potential utility of oral activated charcoal with the hypothesis that such treatment would lower absorption of microbiome derived toxins and ameliorate systemic oxidant stress and inflammation.
    keywords: charcoal; covid-19; stress
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        item: #2214 of 7819
          id: cord-277936-0ytk77fm
      author: Rauscher, E.
       title: Lower State COVID-19 Deaths and Cases with Earlier School Closure in the U.S.
        date: 2020-05-13
       words: 833
      flesch: 56
     summary: To examine whether health benefits of closing schools outweigh the economic and social costs 5 , this study quantifies the relationship between state school closure timing and COVID-19 deaths and cases in the U.S. Using daily cumulative COVID-19 deaths and cases by state from The New York Times, this study examines dates after the first 100 cases in each state until April 27, 2020. COVID-19 has higher symptomatic infection rates among the elderly, suggesting school closures could be unrelated to transmission.
    keywords: deaths; school
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        item: #2215 of 7819
          id: cord-277941-8twjdyjc
      author: Scarci, Marco
       title: Commentary: The double responsibility of the thoracic surgeon at the time of the pandemic: a perspective from the North of Italy
        date: 2020-04-10
       words: 418
      flesch: 38
     summary: 16 The first meaningful evidence emerging from this study is the proportion of severe and critical disease 17 between thoracic surgery patients and the whole COVID population that was 27.3% and 36.4% versus 18 2% and 13.8% respectively, strongly suggesting the possibility that surgery, in itself, can negatively 19 affects outcomes. Epidemic Period].[Article in Chinese COVID-19 Outbreak and Surgical Practice: 54 Unexpected Fatality in Perioperative Period Practical considerations in the anaesthetic management of patients during a 56 COVID-19 epidemic Clinical course of coronavirus disease 2019 in 11 patients after thoracic surgery 58 and challenges in diagnosis Coronavirus Disease 2019 (COVID-19): Role of Chest CT in Diagnosis and 60 Chest CT manifestations of new coronavirus disease 2019 62 (COVID-19): a pictorial review
    keywords: covid-19; surgery
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        item: #2216 of 7819
          id: cord-277992-49mantab
      author: Harikrishnan, S.
       title: Cardiological society of India position statement on COVID-19 and heart failure
        date: 2020-05-13
       words: 2476
      flesch: 38
     summary: COVID-19 patients who are diagnosed as having asymptomatic left ventricular systolic dysfunction or clinically overt heart failure should receive standard guideline directed therapy. This is especially true since heart failure patients may not mount fever.
    keywords: cardiac; china; coronavirus; covid-19; disease; failure; heart; patients
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        item: #2217 of 7819
          id: cord-278022-sc02fyqs
      author: Ogundiran, Akin
       title: On COVID-19 and Matters Arising
        date: 2020-06-05
       words: 3217
      flesch: 45
     summary: It is noteworthy that as early as February 2020, many African countries were at the forefront of proactive actions to stem the spread of the pandemic at the very time that many countries in the global north were in denial and foot-dragging about the disease. As many as two million people in sub-Saharan Africa possibly died from the pandemic (Patterson 1983, p. 501) .
    keywords: africa; archaeological; archaeology; committee; conference; coronavirus; covid-19; heritage; pandemic; safa
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        item: #2218 of 7819
          id: cord-278068-3kg71nf4
      author: Chivese, T.
       title: A meta-review of systematic reviews and an updated meta-analysis on the efficacy of chloroquine and hydroxychloroquine in treating COVID19 infection
        date: 2020-07-30
       words: 9806
      flesch: 44
     summary: Most of the existing systematic reviews have therefore carried out meta-analyses combining data from observational and experimental studies without accounting for the quality of included studies. (which was not certified by peer review) 1 1 magnitude of the effect, the 95% confidence intervals (95%CI) and the number of included studies.
    keywords: analysis; azithromycin; covid-19; hcq; hydroxychloroquine; license; medrxiv; meta; preprint; reviews; studies
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        item: #2219 of 7819
          id: cord-278112-uqxvr77g
      author: Chen, Binzhen
       title: Early experience with convalescent plasma as immunotherapy for COVID‐19 in China: Knowns and unknowns
        date: 2020-06-09
       words: 2816
      flesch: 47
     summary: Administration of Brincidofovir and convalescent plasma in a patient with Ebola virus disease Retrospective comparison of convalescent plasma with continuing high-dose methylprednisolone treatment in SARS patients Use of convalescent plasma therapy in SARS patients in Hong Kong Experience of using convalescent plasma for severe acute respiratory syndrome among healthcare workers in a Taiwan hospital Meta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment? Blood products for Spanish influenza: a future H5N1 treatment? Treatment with convalescent plasma for influenza A (H5N1) infection Feasibility of using convalescent plasma immunotherapy for MERS-CoV infection, Saudi Arabia. From initial studies, convalescent plasma therapy appears effective and safe for COVID‐19.
    keywords: ccp; china; convalescent; covid-19; patients; plasma; treatment
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        item: #2220 of 7819
          id: cord-278130-x83kl052
      author: Wander, Pandora L.
       title: Risk factors for severe COVID-19 illness in healthcare workers: Too many unknowns
        date: 2020-04-27
       words: 775
      flesch: 43
     summary: In addition, we call for more research into the risk factors leading to severe illness among HCWs, defined as COVID-19 requiring hospitalization or admission to the intensive care unit. Despite being younger and healthier than the general population with COVID-19, HCWs have similar rates of severe illness.
    keywords: coronavirus; covid-19; hcws
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        item: #2221 of 7819
          id: cord-278142-xnkqg4ef
      author: Lin, Fang
       title: Cobrotoxin could be an effective therapeutic for COVID-19
        date: 2020-08-25
       words: 1972
      flesch: 37
     summary: Anti-inflammatory activity: NNAV and α-neurotoxins have strong inhibitory effects on inflammation; thus, they could inhibit the cytokine storm caused by SARS-COV2 infection. Clinical features of patients infected with 2019 novel coronavirus in Wuhan The structural loop II of cobrotoxin is the main binding region for nAChR and epitope in the region is conformation-dependent Cobrotoxin extracted from Naja atra venom relieves arthritis symptoms through anti-inflammation and immunosuppression effects in rat arthritis model Involvement of cholinergic system in suppression of formalin-induced inflammatory pain by cobratoxin Cobrotoxin inhibits NFkappa B activation and target gene expression through reaction with NF-kappa B signal molecules Naja naja atra venom ameliorates pulmonary fibrosis by inhibiting inflammatory response and oxidative stress Differential effects of Naja naja atra venom on immune activity Rabies virus infection of IMR-32 human neuroblastoma cells and effect of neurochemical and other agents Peptide derived from cobra venom inhibits HIV infection Modulation of type I interferon system by African swine fever virus Snake venom preparation for drug-resistant human immunodeficiency virus Inhibition of herpes simplex virus replication by cobra alpha-neurotoxoid Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor Pathological findings of COVID-19 associated with acute respiratory distress syndrome Clinical and immunological features of severe and moderate coronavirus disease 2019 Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury Deep vein thrombosis in hospitalized patients with coronavirus disease 2019 (COVID-19) in Wuhan, China: prevalence, risk factors, and outcome Increased expression of CD8 marker on T-cells in COVID-19 patients A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy A long-form alphaneurotoxin from cobra venom produces potent opioid-independent analgesia Conflict of interest: All authors declare no conflict interest.
    keywords: cells; cobrotoxin; covid-19; inhibit; nnav; venom
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        item: #2222 of 7819
          id: cord-278145-3tfcxbfz
      author: Ahmed, Sibtain
       title: Challenges amid COVID-19 times - Review of the changing practices in a clinical chemistry laboratory from a developing country
        date: 2020-06-06
       words: 4209
      flesch: 42
     summary: Like other institutes and industries in the country, clinical laboratories were succumbed to a variety of challenges. Additionally, a literature review of approaches adopted by clinical laboratories worldwide during the pandemic, revealed a report from a United States of America based cytology laboratory, which implemented likewise measures specifically pertaining to social distancing, revision of certain policies, safety measures, re-evaluation of staffing needs, online meetings and virtual academic activities [26] .
    keywords: challenges; country; covid-19; crisis; health; laboratories; laboratory; outbreak; pakistan; pandemic; staff; teams
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        item: #2223 of 7819
          id: cord-278155-4ekdwyrw
      author: Möckel, Martin
       title: How emergency departments prepare for virus disease outbreaks like COVID-19
        date: 2020-05-04
       words: 948
      flesch: 53
     summary: If feasible, patients approaching the ED should be guided with signs to a separate room even before triage in order to prevent contact with other patients waiting for triage. The first patient and other patients were infected by a Chinese colleague during a business contact 7 days before.
    keywords: covid-19; disease; patients
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        item: #2224 of 7819
          id: cord-278165-ym0ynmxy
      author: Pal Singh Gambhir, Raghvinder
       title: Time to pause, to think, and to recalibrate after COVID-19
        date: 2020-05-15
       words: 661
      flesch: 50
     summary: COVID-19 guidelines for triage of vascular surgery patients SAGES statement on potential viral transmission during the use of laparoscopy, and strategies to address that potential risk Why surgeons in Europe and America don't want to operate right now Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1 Joint surgical colleges guidance for surgeons working during the COVID-19 pandemic Clinical guide for the management of vascular patients during the coronavirus pandemic Guidance for surgeons working during the COVID-19 pandemic Response statement from the Vascular Society for Great Britain and Ireland American College of Surgeons.
    keywords: covid-19; patients
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        item: #2225 of 7819
          id: cord-278192-wbpk99yh
      author: Courtney, Alona
       title: The B-MaP-C study: Breast cancer Management Pathways during the COVID-19 pandemic. Study protocol
        date: 2020-07-29
       words: 3594
      flesch: 42
     summary: NICE guideline Caring for patients with cancer in the COVID-19 era Diagnosis and locoregional treatment of patients with breast cancer during the COVID-19 pandemic Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study COVID-19 in breast cancer patients: a cohort at the Institut Curie hospitals in the Paris area Rationalizing breast cancer surgery during the COVID-19 pandemic Guidelines for non-operative diagnostic procedures and reporting in breast cancer screening CholeS Study Group, Population-based cohort study of outcomes following cholecystectomy for benign gallbladder diseases Surgical trainee research collaboratives in the UK: an observational study of research activity and publication productivity The TeaM (Therapeutic Mammaplasty) study: Protocol for a prospective multi-centre cohort study to evaluate the practice and outcomes of therapeutic mammaplasty Breast Reconstruction Research, The iBRA-2 (immediate breast reconstruction and adjuvant therapy audit) study: protocol for a prospective national multicentre cohort study to evaluate the impact of immediate breast reconstruction on the delivery of adjuvant therapy The NeST (neoadjuvant systemic therapy in breast cancer) study -Protocol for a prospective multi-centre cohort study to assess the current utilization and short-term outcomes of neoadjuvant systemic therapies in breast cancer Breast Reconstruction Research, Short-term safety outcomes of mastectomy and immediate implant-based breast reconstruction with and without mesh (iBRA): a multicentre, prospective cohort study Research electronic data capture (REDCap)--a metadata-driven methodology and workflow process for providing translational research informatics support The REDCap consortium: Building an international community of software platform partners Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies Early and locally advanced breast cancer: diagnosis and management (NICE Guideline NG101) Should breast reconstruction and breast oncoplastic procedures be performed during the coronavirus pandemic? British Association of Plastic Reconstructive and Aesthetic Surgeons, Royal College of Nursing, The NHS Information Centre for health and social care, National Mastectomy and Breast Reconstruction Audit. The Royal College of Radiologists (RCR) produced guidelines on the rationalisation of radiotherapy (RT) for breast cancer patients during the pandemic [7] subsequently supported by International guidelines.
    keywords: audit; breast; cancer; covid-19; data; management; pandemic; patients; study
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        item: #2226 of 7819
          id: cord-278246-mnj0zmkn
      author: Hussain, Nowair
       title: A Meta-Analysis on the Effects of Hydroxychloroquine on COVID-19
        date: 2020-08-24
       words: 2991
      flesch: 49
     summary: The mortality rate of patients after applying HCQ on patients with COVID-19 2) The rate of progression/improvement of COVID-19 disease 3) The rate of COVID-19 disease severity, for example, after applying the HCQ treatment, the rate of which patients went on to develop severe conditions such as acute hypoxic respiratory failure and adult respiratory distress syndrome. COVID-19 patients have increased levels of plasma pro-inflammatory cytokines and chemokines
    keywords: covid-19; disease; hcq; patients; rate; studies; study; treatment
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        item: #2227 of 7819
          id: cord-278249-vvhq9vgp
      author: Blot, Mathieu
       title: CXCL10 could drive longer duration of mechanical ventilation during COVID-19 ARDS
        date: 2020-11-02
       words: 6261
      flesch: 38
     summary: COVID-19 ARDS patients required mechanical ventilation (MV) for significantly longer, even after adjustment for potential confounders. It should be evaluated as a candidate biomarker that may predict the duration of MV in COVID-19 ARDS patients.
    keywords: ards; ards patients; concentrations; covid-19; covid-19 ards; csf; cxcl10; cytokine; dna; elf; immune; non; patients; plasma; sars
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        item: #2228 of 7819
          id: cord-278256-dmrtsxik
      author: Qiu, Haiyan
       title: Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study
        date: 2020-03-25
       words: 3460
      flesch: 47
     summary: Fewer children with COVID-19 had obvious symptoms compared with adult patients with COVID-19 and paediatric patients with H1N1 influenza described in previous studies. The comparison of paediatric patients with COVID-19 with adult patients with COVID-19 in the same city (table 3) showed that paediatric patients had a significantly lower prevalence of abnormal values of several variables indicating disease severity, such as fever (36% for children and 86% for adults), cough (19% and 62%), pneumonia (53% and 95%), elevated C-reactive protein (3% and 49%), and severe disease type (0% and 23%; p<0·0001 for all features).
    keywords: children; coronavirus; covid-19; fever; patients; pneumonia; sars
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        item: #2229 of 7819
          id: cord-278271-rpq62xhl
      author: Lyu, Jinglu
       title: Reflection on lower rates of COVID-19 in children: does childhood immunizations offer unexpected protection?
        date: 2020-05-15
       words: 4649
      flesch: 38
     summary: Eleven T and B lymphocyte tests were used to analyze the changes of specific immune cells. Immune cells are able to clear the pathogen without causing a severe inflammatory response, resulting in covert infection or mild to moderate symptoms with short course, which is called immune fitness (41) .The severity of the infection is not necessarily related to the load of infection, but rather to host fitness, the balance between killing the pathogen and tolerance.
    keywords: cases; cells; children; coronavirus; covid-19; immune; immunity; infection; patients; response; sars
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        item: #2230 of 7819
          id: cord-278300-6cr9h7no
      author: Lu, X.
       title: Classification of COVID-19 in intensive care patients: towards rational and effective clinical triage
        date: 2020-04-11
       words: 1273
      flesch: 40
     summary: The study is limited by ignoring the effect of treatment, but we believe that such classification of COVID-19 in intensive care patients could help in early warning of the disease and would provide effective triage for the treatment and management of individual patients, allowing for a more rational allocation of scarce medical resources in a resource constrained environment. key: cord-278300-6cr9h7no authors: Lu, X.; Wang, Y.; Chen, T.; Li, Y.; Wang, J.; Yan, F. title: Classification of COVID-19 in intensive care patients: towards rational and effective clinical triage date: 2020-04-11 journal: nan DOI: 10.1101/2020.04.09.20058909 sha: doc_id: 278300 cord_uid: 6cr9h7no The number of pertinent researches of COVID-19 has increased rapidly but they mainly focused on the description of general information of patients with confirmed infection.
    keywords: care; data; patients; preprint
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        item: #2231 of 7819
          id: cord-278306-wdj5v3rh
      author: Alharthy, Abdulrahman
       title: COVID-19 in a patient with a flare of systemic lupus erythematosus: a rare case-report
        date: 2020-10-15
       words: 2040
      flesch: 41
     summary: Old age and underlying disorders such as arterial hypertension, diabetes mellitus, end-stage kidney disease (ESKD), and compromised immune status are risk factors affecting the morbidity and the mortality of COVID-19 patients However, lupus pneumonitis occurs only in a minority (1-4%) of SLE patients and carries a poor prognosis; while its therapy is still empiric.
    keywords: administration; covid-19; lupus; patients; pneumonitis; sle
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        item: #2232 of 7819
          id: cord-278313-gadui4r7
      author: Zakeri, R.
       title: A case-control and cohort study to determine the relationship between ethnic background and severe COVID-19
        date: 2020-07-10
       words: 5159
      flesch: 44
     summary: An alternative driver of higher admission risk in Black and Mixed ethnicity people may be that they are more likely once infected to progress to disease that requires admission (noting that an increase in mild infections per se should not affect admission risk or mortality). In conditional logistic regression analyses, Black and Mixed/Other ethnicity were associated with higher admission risk than white (OR 3.12
    keywords: admission; available; covid-19; ethnicity; hospital; license; medrxiv; patients; preprint
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        item: #2233 of 7819
          id: cord-278325-ykcd7d59
      author: Cheung, Carmen Ka Man
       title: Coronavirus Disease 2019 (COVID-19): A Haematologist's Perspective
        date: 2020-07-28
       words: 7682
      flesch: 35
     summary: Thrombocytopenia, coagulation abnormalities, and disseminated intravascular coagulation were observed in COVID-19 patients, especially those with critical illness and non-survivors. [45] evaluated lymphocyte subsets in 103 patients, which revealed that CD3+, CD4+, and CD8+ T cells and NK cells were significantly decreased in COVID-19 patients with a more severe decrease in CD8+ T cells compared with CD4+ T cells.
    keywords: admission; blood; cells; clinical; coronavirus; cov-2; covid-19; disease; infection; lymphocyte; non; patients; platelet; risk; sars; study; treatment
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        item: #2234 of 7819
          id: cord-278339-6ddsj014
      author: Gianfrancesco, Milena
       title: Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry
        date: 2020-05-29
       words: 5391
      flesch: 34
     summary: Age, sex, smoking status, rheumatic disease diagnosis, comorbidities and rheumatic disease medications taken immediately prior to infection were analysed. key: cord-278339-6ddsj014 authors: Gianfrancesco, Milena; Hyrich, Kimme L; Al-Adely, Sarah; Carmona, Loreto; Danila, Maria I; Gossec, Laure; Izadi, Zara; Jacobsohn, Lindsay; Katz, Patricia; Lawson-Tovey, Saskia; Mateus, Elsa F; Rush, Stephanie; Schmajuk, Gabriela; Simard, Julia; Strangfeld, Anja; Trupin, Laura; Wysham, Katherine D; Bhana, Suleman; Costello, Wendy; Grainger, Rebecca; Hausmann, Jonathan S; Liew, Jean W; Sirotich, Emily; Sufka, Paul; Wallace, Zachary S; Yazdany, Jinoos; Machado, Pedro M; Robinson, Philip C title: Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry date: 2020-05-29 journal:
    keywords: anti; cases; covid-19; data; disease; fees; hospitalisation; inhibitors; patients; registry; use
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        item: #2235 of 7819
          id: cord-278341-pnrh3r2j
      author: Monzani, Alice
       title: Management of a suspected case of 2019 novel coronavirus infection in a 4‐year old child: A simulation scenario
        date: 2020-08-10
       words: 1271
      flesch: 42
     summary: In this regard, it would be particularly useful in Countries not already critically involved in the pandemic, and to address not only residents but also paediatric emergency practitioners, in the front line of the management of suspected COVID-19 cases. The implementation of the skills in PPE use is of paramount importance to prepare health-care workers to proficiently and safely work departments dealing with suspected COVID-19 cases.
    keywords: covid-19; paediatric; scenario; simulation
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        item: #2236 of 7819
          id: cord-278389-cgktbqf9
      author: Shaw, William S.
       title: Opening the Workplace After COVID-19: What Lessons Can be Learned from Return-to-Work Research?
        date: 2020-06-19
       words: 1832
      flesch: 34
     summary: NEJM Perspective Supervisor and organizational factors associated with supervisor support of job accommodations for low back injured workers Prevention of work disability due to musculoskeletal disorders: the challenge of implementing evidence Return-to-work outcomes following work disability: stakeholder motivations, interests and concerns Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Just as with return-to-work after injury, employers may struggle to maintain uniform and fair practices while also being responsive to the concerns of individual workers, and it will be important to involve multiple stakeholders in this process
    keywords: covid-19; return; work; workers; workplace
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        item: #2237 of 7819
          id: cord-278406-n5e3a09i
      author: Macauley, Precious
       title: CORTICOSTEROIDS IN THE TREATMENT OF SEVERE COVID-19 LUNG DISEASE: THE PULMONOLOGY PERSPECTIVE FROM THE FIRST UNITED STATES EPICENTER
        date: 2020-08-21
       words: 1495
      flesch: 15
     summary: While caring for scores of severe COVID-19 lung disease patients and repeatedly witnessing a striking clinicoradiographic response to pulse corticosteroids, we were disheartened by the initial negativity towards corticosteroids expressed by, among others, our infectious disease colleagues (Massachusetts General Hospital, 2020; the use of corticosteroids in pulmonary medicine, including at pulse dose, for certain diffuse lung diseases, a practice that is readily applied even to novel entities such as e-cigarette or vaping product-use associated lung injury (EVALI) that lack any evidence base (Layden et al, 2020) . It is worth considering that corticosteroids were administered based on clinicians' discretion a median of three days into ICU stay at a median dose in methylprednisolone equivalents of 60mg, very different from the one gram of methylprednisolone starting on the day of ICU arrival and continued for three days that has been our practice with severe COVID-19 lung disease.
    keywords: acute; covid-19; disease; lung; syndrome
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        item: #2238 of 7819
          id: cord-278418-i8cbrs7y
      author: Leitner, Stephan
       title: On the dynamics emerging from pandemics and infodemics
        date: 2020-08-31
       words: 2467
      flesch: 30
     summary: The spread of awareness and its impact on epidemic outbreaks Act II: a fine-grained analysis of regional variations in traffic fatalities in the aftermath of the terrorist attacks COVID-19: Risk perception and coping strategies Dread risk, September 11, and fatal traffic accidents Application of risk concepts to wildlife management: special issue introduction Experiments on belief formation in networks Analysis of results from the joint external evaluation: Examining its strength and assessing for trends among participating countries Information needs and risk perception as predictors of risk information seeking Risk perception and terrorism: applying the psychometric paradigm COVID-19 global cases A review of human factors challenges of complex adaptive systems: discovering and understanding chaos in human performance Individual disaster preparedness: explaining disaster-related information seeking and preparedness behavior in Switzerland Avoiding the death risk of avoiding a dread risk: the aftermath of March 11 in Spain Ready or not, patients will present: improving urban pandemic preparedness. It is, therefore, of ultimate importance to understand how people select information sources during hazardous events and how information dynamics interfere with risk perception and behavioral dynamics (Cinelli et al. 2020 ; Sharot and Sunstein 2020).
    keywords: behavior; pandemic; preparedness; risk
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        item: #2239 of 7819
          id: cord-278440-vti6xp9v
      author: Paraiso, Ines L
       title: Potential use of polyphenols in the battle against COVID-19
        date: 2020-09-09
       words: 2342
      flesch: 37
     summary: An in silico strategy unveils a hope against CORONA Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors The SARS-CoV-2 main protease as drug target Diarylheptanoids from Alnus japonica inhibit papain-like protease of severe acute respiratory syndrome coronavirus A: An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study This study screened a total of 33 molecules using a blind molecular docking approach to identify possible inhibitors of the SARS-CoV-2 main protease Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases Papain-like protease (PLpro) inhibitory effects of cinnamic amides from Tribulus terrestris fruits Chalcones isolated from Angelica keiskei inhibit cysteine proteases of SARS-CoV Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds of Psoralea corylifolia Evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris Evaluation of green tea polyphenols as novel corona virus (SARS CoV-2) main protease (Mpro) inhibitors -an in silico docking and molecular dynamics simulation study Mechanism of inhibition of Ebola virus RNA-dependent RNA polymerase by remdesivir Effective inhibition of MERS-CoV infection by resveratrol This study is the first to demonstrate that resveratrol is a potent anti-MERS agent in vitro Candidate drugs against SARS-CoV-2 and COVID-19 Indomethacin and resveratrol as potential treatment adjuncts for SARS-CoV-2/COVID-19 Plant-derived natural polyphenols as potential antiviral drugs against SARS-CoV-2 via RNA-dependent RNA polymerase (RdRp) inhibition: An in-silico analysis Reducing mortality from 2019-nCoV: host-directed therapies should be an option IL-6 The newly emerged SARS-like coronavirus HCoV-EMC also has an Achilles' heel: current effective inhibitor targeting a 3C-like protease Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease Identification of potent COVID-19 main protease (Mpro) inhibitors from natural polyphenols:
    keywords: ace2; cov-2; covid-19; polyphenols; potential; pro; protease; sars
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        item: #2240 of 7819
          id: cord-278459-27lppl6x
      author: Banjar, Weam M.
       title: Healthcare worker's mental health dilemma during COVID-19 pandemic: A reflection on the KSA experience
        date: 2020-07-17
       words: 1857
      flesch: 46
     summary: The focus was on the population's psychological needs during the pandemic and its impact on mental health. Psychiatrists, psychologists, and social workers needed to be equipped with the tools to assess mental health and deliver the appropriate care.
    keywords: cases; covid-19; hcws; health; pandemic
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        item: #2241 of 7819
          id: cord-278477-9a7gmzz3
      author: Huh, Kyungmin
       title: Impact of obesity, fasting plasma glucose level, blood pressure, and renal function on the severity of COVID-19: a matter of sexual dimorphism?
        date: 2020-10-21
       words: 3235
      flesch: 44
     summary: Propensity scores (PS) of severe COVID-19 risk were calculated using logistic regression with the following covariates: age, sex, coverage for low income, and CCI. This retrospective study compared BP, and metabolic and kidney function parameters between COVID-19 patients with severe disease (including fatalities) and those with mild-tomoderate disease.
    keywords: covid-19; disease; health; levels; patients; risk; sex; study
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        item: #2242 of 7819
          id: cord-278536-b4eyegx5
      author: Piazza, Gregory
       title: Registry of Arterial and Venous Thromboembolic Complications in Patients With COVID-19
        date: 2020-11-03
       words: 1472
      flesch: 25
     summary: Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in COVID-19 and haemostasis: a position paper from Italian Society on Thrombosis and Haemostasis (SISET) Incidence of venous thromboembolism in hospitalized patients with COVID-19 Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19 Endothelial cell infection and endotheliitis in COVID-19 Autopsy findings and venous thromboembolism in patients with COVID-19 Prevention, diagnosis and treatment of VTE in patients with coronavirus disease 2019: CHEST guideline and expert panel report Scientific and Standardization Committee communication: clinical guidance on the diagnosis, prevention and treatment of venous thromboem Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Systematic review with meta-analysis of the accuracy of diagnostic tests for COVID-19 Research electronic data capture (REDCap)-a metadata-driven methodology and workflow process for providing translational research informatics support Third universal definition of myocardial infarction Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients A proportional hazards model for the subdistribution of a competing risk Bias reduction of maximum likelihood estimates Impact of cardiovascular disease and cardiac injury on in-hospital mortality in patients with COVID-19: a systematic review and meta-analysis Acute pulmonary embolism and COVID-19 Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019 Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: an updated analysis Pharmacological agents targeting thromboinflammation in COVID-19: review and implications for future research Incidence of asymptomatic deep vein thrombosis in patients with COVID-19 pneumonia and elevated D-dimer levels key: cord-278536-b4eyegx5 authors: Piazza, Gregory; Campia, Umberto; Hurwitz, Shelley; Snyder, Julia E.; Rizzo, Samantha M.; Pfeferman, Mariana B.; Morrison, Ruth B.; Leiva, Orly; Fanikos, John; Nauffal, Victor; Almarzooq, Zaid; Goldhaber, Samuel Z. title: Registry of Arterial and Venous Thromboembolic Complications in Patients With COVID-19 date: 2020-11-03 journal: J Am Coll Cardiol DOI: 10.1016/j.jacc.2020.08.070 sha: doc_id: 278536 cord_uid: b4eyegx5 BACKGROUND: Cardiovascular complications, including myocardial infarction, ischemic stroke, and pulmonary embolism, represent an important source of adverse outcomes in coronavirus disease-2019 (COVID-19).
    keywords: arterial; care; cohort; covid-19; patients
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        item: #2243 of 7819
          id: cord-278558-znqscgxb
      author: Carvalho, Tatiana Aline
       title: COVID-19 in Brazil: 150,000 deaths and the Brazilian underreporting
        date: 2020-10-21
       words: 1415
      flesch: 42
     summary: A significant Spearman correlation coefficient (CC) was found between the excess mortality rate by natural causes (number of cases) and (i) number of COVID-19 cases (CC=0.765; P-value≤0.001); (ii) number of deaths by COVID-19 (CC=0.862; P-value≤0.001); (iii) CFR (CC=0.664; P-value≤0.001) and (iv) incidence per 1000,000 inhabitants for COVID-19 (CC=-0.530; P-value=0.004); as well as, excess deaths by natural causes per expected deaths by natural causes with the mortality per 100,000 inhabitants due COVID-19 (CC=0.464; P-value=0.015). Brazilian regions presented a rise in the percentage of excess deaths, with the lowest rates in the South region (5%) and the highest in the North region (48%).
    keywords: causes; covid-19; deaths
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        item: #2244 of 7819
          id: cord-278581-4vhpoi87
      author: Chaudhary, Varun
       title: National survey of Canadian Retina Society members on guidelines for ophthalmic care during the COVID-19 crisis: Canadian Retina Research Network (CR2N) COVID-19 Steering Committee analysis
        date: 2020-07-09
       words: 701
      flesch: 41
     summary: key: cord-278581-4vhpoi87 authors: Chaudhary, Varun; Rosenberg, Daniel; Barbosa, Joshua; Qian, Cynthia; Berger, Alan; Whelan, James; Kherani, Amin; Samad, Arif; Noble, Jason title: National survey of Canadian Retina Society members on guidelines for ophthalmic care during the COVID-19 crisis: Canadian Retina Research Network (CR2N) COVID-19 Steering Committee analysis date: 2020-07-09 journal: Can J Ophthalmol DOI: 10.1016/j.jcjo.2020.06.001 sha: doc_id: 278581 cord_uid: 4vhpoi87 nan Steering Committee to assess awareness of, confidence in, and adherence to recent guidelines released by the Canadian Ophthalmology Society (COS) and Canadian Retina Society (CRS) for ophthalmic care during the COVID-19 pandemic. The survey results demonstrated strong awareness among CRS members of the guidelines recently released by COS and CRS in response to the COVID-19 crisis, suggesting that the mechanisms of dissemination used by these governing bodies were successful at reaching their physician members in a timely manner.
    keywords: covid-19; guidance
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        item: #2245 of 7819
          id: cord-278589-ios3cuxc
      author: Golinelli, D.
       title: How the COVID-19 pandemic is favoring the adoption of digital technologies in healthcare: a rapid literature review
        date: 2020-05-01
       words: 5043
      flesch: 44
     summary: key: cord-278589-ios3cuxc authors: Golinelli, D.; Boetto, E.; Carullo, G.; Landini, M. P.; Fantini, M. P. title: How the COVID-19 pandemic is favoring the adoption of digital technologies in healthcare: a rapid literature review date: 2020-05-01 journal: nan DOI: 10.1101/2020.04.26.20080341 sha: doc_id: 278589 cord_uid: ios3cuxc Background. We conducted a rapid literature review searching PubMed and MedrXiv with terms considered adequate to find relevant literature on the use of digital technologies in response to COVID-19.
    keywords: care; covid-19; data; digital; health; literature; pandemic; solutions; surveillance; technologies
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        item: #2246 of 7819
          id: cord-278609-zxdd06ur
      author: Sarac, Benjamin A.
       title: The Impact of COVID-19-based Suspension of Surgeries on Plastic Surgery Practices: A Survey of ACAPS Members
        date: 2020-08-03
       words: 2771
      flesch: 41
     summary: 278609 cord_uid: zxdd06ur The coronavirus disease 2019 (COVID-19) pandemic led to a drastic decline in the number of elective surgeries performed in the United States. Many national societies and local governments provided recommendations for surgeons to initially suspend and progressively resume elective surgery.
    keywords: covid-19; plastic; procedures; surgeons; surgery; survey
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        item: #2247 of 7819
          id: cord-278620-mezsjdyb
      author: Choy, Kay W.
       title: An urgent call to clinicians and researchers: 2020 acuity required when assessing and reporting laboratory abnormalities in COVID‐19
        date: 2020-07-12
       words: 1050
      flesch: 38
     summary: The diagnostic criteria for GDM were based on the Hyperglycaemia and Adverse Pregnancy Outcome study, which had strict protocol for glucose sample handling. 8 I call on clinicians and researchers to consider the preanalytical, analytical and post-analytical aspects of laboratory testing when reviewing or publishing laboratory results in this COVID-19 pandemic.
    keywords: covid-19; glucose; laboratory; testing
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        item: #2248 of 7819
          id: cord-278629-8fva8fwr
      author: Zhou, Jun
       title: Differential diagnosis between the coronavirus disease 2019 and Streptococcus pneumoniae pneumonia by thin-slice CT features
        date: 2020-10-06
       words: 2469
      flesch: 37
     summary: However, there is no report on differentiation of chest CT findings between COVID-19 patients and patients with S. pneumoniae pneumonia. Thus, this study retrospectively analyzed chest CT findings in COVID-19 patients and compared them with chest CT findings in patients with S. pneumoniae pneumonia in order to describe CT features which are more common in patients with COVID-19 when compared to patients with S. pneumoniae pneumonia, and which may aid in differentiating these two entities clinically.
    keywords: chest; coronavirus; covid-19; patients; pneumonia
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        item: #2249 of 7819
          id: cord-278638-2dm54f6l
      author: Huang, Ian
       title: Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysis
        date: 2020-05-24
       words: 3107
      flesch: 46
     summary: Regressionbased Harbord's test showed no evidence of small-study effects (p = 0.086) for lymphopenia and severe COVID-19 outcome. Lymphocyte count has been a marker of interest since the first COVID-19 publication.
    keywords: analysis; count; covid-19; lymphocyte; meta; outcome; patients
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        item: #2250 of 7819
          id: cord-278649-ge9ike2c
      author: Makaronidis, Janine
       title: Seroprevalence of SARS-CoV-2 antibodies in people with an acute loss in their sense of smell and/or taste in a community-based population in London, UK: An observational cohort study
        date: 2020-10-01
       words: 4283
      flesch: 54
     summary: A total of 80.4% of participants with smell loss and 86.0% (n = 307) of those with complete smell loss had a positive test result. Seropositivity for SARS-CoV-2 was 3 times more likely in participants with smell loss (OR 2.86; 95% CI 1.27–6.36; p < 0.001) compared with those with taste loss.
    keywords: antibodies; cov-2; covid-19; loss; participants; sars; smell; taste
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        item: #2251 of 7819
          id: cord-278672-pxzsntfg
      author: Milenkovic, Aleksandar
       title: Extensions and Adaptations of Existing Medical Information System in Order to Reduce Social Contacts During COVID-19 Pandemic
        date: 2020-06-16
       words: 4611
      flesch: 41
     summary: Before the beginning of COVID-19 pandemic MIS MEDIS.NET did not have specifically developed software functionalities (modules, subsystems) which would help healthcare workers and patients to combat seasonal and exceptional pandemics. The therapy of chronic patients has been prolonged for 6 months via an electronic prescription.
    keywords: covid-19; data; disease; health; information; mis; pandemic; patients; system
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        item: #2252 of 7819
          id: cord-278676-p13ev4cg
      author: Pontiroli, Antonio E.
       title: Is blood glucose or obesity responsible for the bad prognosis of COVID-19 in obesity -diabetes?
        date: 2020-07-27
       words: 488
      flesch: 41
     summary: [3] , but DM patients show a worse prognosis Intensifying the treatment of obese patients, who are also diabetic, might be important in yielding a better prognosis.
    keywords: covid-19; obesity
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        item: #2253 of 7819
          id: cord-278701-ub9j2f9i
      author: Umer, Fahad
       title: Dental services during the COVID‐19 pandemic: A tertiary care hospital experience
        date: 2020-08-20
       words: 2232
      flesch: 45
     summary: key: cord-278701-ub9j2f9i authors: Umer, Fahad; Motiwala, Momina title: Dental services during the COVID‐19 pandemic: A tertiary care hospital experience date: 2020-08-20 journal: Spec Care Dentist DOI: 10.1111/scd.12510 sha: doc_id: 278701 cord_uid: ub9j2f9i The Aga Khan University is the largest tertiary care hospital in the biggest metropolis of Pakistan, in this paper six weeks of experience during the COVID‐19 pandemic is shared, we will discuss the measures that were taken to mitigate the spread of COVID‐19 amongst dental health care providers (DHCPS) and provide a neoteric workflow for the provision of safe dental care as dental services move towards normalcy. 8 Dentoalveolar abscess, acute-pericoronitis, pulpal, and periapical infections were the most common reasons for patients to seek emergency dental care, which is in concordance to other dental literature.
    keywords: care; clinic; covid-19; hospital; patients; test
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        item: #2254 of 7819
          id: cord-278702-hacapz8l
      author: Hirshberg, Adi
       title: Care of critically ill pregnant patients with coronavirus disease 2019: a case series
        date: 2020-05-01
       words: 1910
      flesch: 39
     summary: A report, from Singapore, that was published during the early stages of the pandemic, chronicled a total of 55 published cases of pregnant patients with COVID-19 disease, with no reports of mortality and only 1 report of a requirement for mechanical ventilation. The clinical courses of 5 pregnant women with severe cases of COVID-19 disease, all requiring mechanical ventilation, are described below and summarized in the Table.
    keywords: case; covid-19; delivery; disease; patients
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        item: #2255 of 7819
          id: cord-278710-2fiyzl5u
      author: Kalner, Samantha
       title: Periorbital Erythema as a Presenting Sign of Covid-19
        date: 2020-05-11
       words: 635
      flesch: 32
     summary: The timing of the reported cutaneous manifestations observed has also varied, with some patients presenting with cutaneous findings at the onset of the COVID-19 symptoms, while other patients develop cutaneous involvement after infection has progressed and they have been hospitalized 1 . Cutaneous manifestations in COVID 19: a first perspective Clinical Characteristics of Coronavirus Disease 2019 in China COVID-19 can present with a rash and be mistaken for Dengue Cutaneous manifestations in COVID 19: a new contribution Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19 Characteristics of Ocular Findings of Patients With Coronavirus Disease
    keywords: covid-19; patients
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        item: #2256 of 7819
          id: cord-278721-g5zqebju
      author: Jakhmola, Shweta
       title: Comorbidity Assessment Is Essential During COVID-19 Treatment
        date: 2020-08-04
       words: 3750
      flesch: 38
     summary: Emerging data depicts that COVID-19 patients have various aspects associated with hospitalization and severity. Interestingly, an increase in the number of COVID-19 patients with comorbidities is reported .
    keywords: comorbidities; covid-19; diseases; et al; patients
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        item: #2257 of 7819
          id: cord-278735-bu2w2ox6
      author: Zhang, Y.
       title: Gastrointestinal tract symptoms in coronavirus disease 2019: Analysis of clinical symptoms in adult patients
        date: 2020-03-27
       words: 2003
      flesch: 58
     summary: [4] [5] Recent studies report that gastrointestinal tract symptoms are rarely observed in COVID-19 patients, 2-3 observed in about 3.0% of cases. Furthermore, in contrast to cough and other symptoms, diarrhoea in COVID-19 patients lasted for a short duration and mostly occurred as mushy stools instead of watery diarrhoea in SARS.
    keywords: covid-19; medrxiv; preprint; symptoms
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        item: #2258 of 7819
          id: cord-278775-xntvl7jp
      author: Gangaputra, Sapna S.
       title: Ocular symptoms among non-hospitalized patients who underwent COVID-19 testing
        date: 2020-06-22
       words: 955
      flesch: 42
     summary: COVID-19 negative patients had higher rates of self-reported drug 108 allergies; this is of unclear clinical significance. The stay at home 46 restrictions and limited access to ambulatory ophthalmology care may inadvertently delay the 47 recognition of ocular signs and symptoms associated with Currently, we have minimal data on the incidence and severity of ocular manifestations of non-49 hospitalized COVID-19 positive patients.
    keywords: covid-19; patients; symptoms
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        item: #2259 of 7819
          id: cord-278826-096v6taj
      author: Pitscheider, Lea
       title: Muscle involvement in SARS‐CoV‐2 infection
        date: 2020-09-30
       words: 2649
      flesch: 46
     summary: Furthermore, 5.4% of influenza patients, compared to 1.4% of COVID-19 patients, presented CK levels exceeding 1000. However, baseline CK in ICU-admitted patients was higher in influenza than in COVID-19 patients, despite similar CRP levels.
    keywords: covid-19; disease; hyperckemia; influenza; patients
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        item: #2260 of 7819
          id: cord-278839-uu2wlpmp
      author: Alberca, Ricardo Wesley
       title: Pregnancy, Viral Infection, and COVID-19
        date: 2020-07-07
       words: 7256
      flesch: 30
     summary: retrospective cohort study Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis Antibodies in infants born to mothers with COVID-19 pneumonia Lack of vertical transmission of severe acute respiratory syndrome coronavirus 2, China First case of neonatal infection due to COVID 19 in Spain COVID-19 vaginal delivery-a case report Analysis of the pregnancy outcomes in pregnant women with COVID-19 in Hubei Province Coronavirus disease 2019 (COVID-19) during pregnancy: a case series COVID-19 in a 26-week preterm neonate COVID-19 Infection in First Trimester of Pregnancy Marked by a Liver Cytolysis: A Case Report Evidence of mother-to-newborn infection with COVID-19 Maternal death due to COVID-19 Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Testicular effects following in utero exposure to the antivirals acyclovir and ganciclovir in rats Pathological findings of COVID-19 associated with acute respiratory distress syndrome Interleukin-2 receptor serum concentrations in normal pregnancy and pre-eclampsia The involvement of inflammatory cytokines in the pathogenesis of recurrent miscarriage Abnormal IL-2 receptor levels in non-pregnant women with a history of recurrent miscarriage IL-7/IL-7R signaling pathway might play a role in recurrent pregnancy losses by increasing inflammatory Th17 cells and decreasing Treg cells Association of tumor necrosis factoralpha 308G/A polymorphism with recurrent miscarriages in women Human tumour necrosis factor: physiological and pathological roles in placenta and endometrium Tumor necrosis factor-α and pregnancy complications: a prospective study Placental TNF-α signaling in illness-induced complications of pregnancy Programming of fetal insulin resistance in pregnancies with maternal obesity by ER stress and inflammation TNF-alpha is a predictor of insulin resistance in human pregnancy Maternal circulating concentrations of tumor necrosis factor-alpha, leptin, and adiponectin in gestational diabetes mellitus: a systematic review and meta-analysis Prenatal immune challenge affects growth, behavior, and brain dopamine in offspring In utero exposure to virus infections and the risk of developing anorexia nervosa Maternal infection: window on neuroimmune interactions in fetal brain development and mental illness Prenatal exposure to maternal infection alters cytokine expression in the placenta, amniotic fluid, fetal brain Prenatal LPS-exposurea neurodevelopmental rat model of schizophrenia-differentially affects cognitive functions, myelination and parvalbumin expression in male and female offspring Prenatal lipopolysaccharide exposure promotes dyslipidemia in the male offspring rats Prenatal viral exposure followed by adult stress produces glucose intolerance in a mouse model Prenatal initiation of endotoxin airway exposure prevents subsequent allergeninduced sensitization and airway inflammation in mice Thrown off balance: the effect of antenatal inflammation on the developing lung and immune system Maternal stress during pregnancy increases neonatal allergy susceptibility: role of glucocorticoids Hertz-Picciotto I. Is maternal influenza or fever during pregnancy associated with autism or developmental delays? Although there is little knowledge about placental findings associated with the common coronaviruses, Ng et al. reported placental pathology in seven women with SARS infection in Hong Kong (43) .
    keywords: cells; coronavirus; cov-2; covid-19; disease; expression; infection; inflammatory; influenza; maternal; placental; pregnancy; response; sars; syndrome; virus; women
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        item: #2261 of 7819
          id: cord-278850-q5eg1uhl
      author: Yoshida, Shuntaro
       title: Real-world clinical data of endoscopy-based cancer detection during the emergency declaration for COVID-19 in Japan
        date: 2020-10-16
       words: 1090
      flesch: 35
     summary: Second, the indications for endoscopy were limited as follows: Symptomatic patients, patients with abnormalities in other tests, patients with previous appointments, and patients who strongly wished for investigation. Therefore, we examined the significance of endoscopy based on the recommendation of Asian-Pacific Society for Digestive Endoscopy and Japan Gastroenterological Endoscopy Society during the COVID-19 pandemic by evaluating the details of gastrointestinal endoscopy performed during the declaration of emergency in Japan.
    keywords: emergency; endoscopy; patients
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        item: #2262 of 7819
          id: cord-278870-pct184oa
      author: Finell, Eerika
       title: The Combined Effect of Perceived COVID-19 Infection Risk at Work and Identification with Work Community on Psychosocial Wellbeing among Finnish Social Sector and Health Care Workers
        date: 2020-10-19
       words: 5019
      flesch: 52
     summary: Our results support the hypothesis that those with low work community identification and high perceived COVID-19 infection risk at work show greater frequencies of stress symptoms than those with high identification and high perceived infection risk. After all background variables were included, participants who reported high perceived infection risk and low work community identification reported stress symptoms more often than those who reported high perceived risk and high identification (p = 0.010).
    keywords: covid-19; health; identification; risk; stress; work
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        item: #2263 of 7819
          id: cord-278881-bj5ebk2s
      author: Binagwaho, Agnes
       title: Changing the COVID-19 Narrative in Africa: Using an Implementation Research Lens to Understand Successes and Plan for Challenges Ahead
        date: 2020-08-19
       words: 2416
      flesch: 33
     summary: Implementation science methods can serve to develop knowledge at a country and regional level on how to identify, utilize, and address these and other contextual factors, and inform relevant evidence-based interventions and implementation strategies. Implementation science methods can serve to develop knowledge at a country and regional level on how to identify, utilize, and address these and other contextual factors, and inform relevant evidence-based interventions and implementation strategies.
    keywords: covid-19; health; implementation; interventions; strategies
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        item: #2264 of 7819
          id: cord-278900-3rfb1b71
      author: Fell, Michael J.
       title: Validity of energy social research during and after COVID-19: challenges, considerations, and responses
        date: 2020-06-13
       words: 6188
      flesch: 36
     summary: key: cord-278900-3rfb1b71 authors: Fell, Michael J.; Pagel, Laura; Chen, Chien-fei; Goldberg, Matthew H.; Herberz, Mario; Huebner, Gesche M.; Sareen, Siddharth; Hahnel, Ulf J.J. title: Validity of energy social research during and after COVID-19: challenges, considerations, and responses date: 2020-06-13 journal: Energy Res Soc Sci DOI: 10.1016/j.erss.2020.101646 sha: doc_id: 278900 cord_uid: 3rfb1b71 Measures to control the spread of coronavirus disease 2019 (COVID-19) are having unprecedented impacts on people’s lives around the world. We argue that they are especially important for those domains of energy social research that claim broad generalisability to their findings and insights, with limited focus on context.
    keywords: covid-19; data; energy; findings; measures; pandemic; research; researchers; validity; variables
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        item: #2265 of 7819
          id: cord-278907-xuq3iay5
      author: Papoutsi, Eleni
       title: Global burden of COVID-19 pandemic on healthcare workers
        date: 2020-07-06
       words: 848
      flesch: 44
     summary: key: cord-278907-xuq3iay5 authors: Papoutsi, Eleni; Giannakoulis, Vassilis G.; Ntella, Vasiliki; Pappa, Sofia; Katsaounou, Paraskevi title: Global burden of COVID-19 pandemic on healthcare workers date: 2020-07-06 journal: ERJ Open Res DOI: 10.1183/23120541.00195-2020 sha: doc_id: 278907 cord_uid: xuq3iay5 Provision of PPE, placing experienced HCWs mostly in organisational positions, increasing testing, minimising exposure by adjusting shift schedules, and providing food and sleep facilities could be some restorative measures to protect HCWs from #COVID19 https://bit.ly/2zcVARW Contrary to aforementioned number of infected HCWs from WHO, our research revealed ⩾67 569 cases of COVID-19 infected HCWs. Interestingly, countries in Asia seem to have lower infection rates among HCWs; this could possibly be attributed either to the readiness of these countries to deal with outbreaks [5, 6] or to the relatively lower health workforce density in south-east Asia [7] .
    keywords: covid-19; hcws; health
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        item: #2266 of 7819
          id: cord-278932-wp4kimij
      author: Been, Jasper V
       title: Impact of COVID-19 mitigation measures on the incidence of preterm birth: a national quasi-experimental study
        date: 2020-10-14
       words: 5134
      flesch: 42
     summary: 14 As such, exploration of the possible link between national lockdown measures and a decrease in preterm births is needed, and if confirmed, so is identification of the underlying mechanisms to inform and optimise future approaches to prevent preterm birth from devastating families' lives. key: cord-278932-wp4kimij authors: Been, Jasper V; Burgos Ochoa, Lizbeth; Bertens, Loes C M; Schoenmakers, Sam; Steegers, Eric A P; Reiss, Irwin K M title: Impact of COVID-19 mitigation measures on the incidence of preterm birth: a national quasi-experimental study date: 2020-10-14 journal:
    keywords: birth; covid-19; data; march; measures; mitigation; mitigation measures; national; preterm; study
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        item: #2267 of 7819
          id: cord-278933-bwhi4hcl
      author: Shoji, Hamilton
       title: Structured thoracic computed tomography report for COVID-19 pandemic
        date: 2020-04-03
       words: 1060
      flesch: 25
     summary: Cases in U.S [Internet Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT Imaging profile of the covid-19 infection: radiologic findings and literature review CT Imaging Features of 2019 Novel coronavirus (2019-nCoV) Chest Imaging Appearance of COVID-19 Infection Electronic address: https: // www.lancovid.org. In patients with tomographic findings more suggestive of other type of infection which obviously must not be neglected amidst the pandemic, we have described the changes and concluded as follows: Such findings are compatible with pulmonary infectious process, and its characteristics are not typically observed in cases of pulmonary involvement by COVID-19; other etiologic agents should be initially considered in the differential diagnosis.
    keywords: cases; covid-19; findings; report
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        item: #2268 of 7819
          id: cord-278971-tb2he1cb
      author: Valeri, Anthony
       title: COVID-19 and ESRD: Entering a New Era of Uncertainty
        date: 2020-07-25
       words: 981
      flesch: 43
     summary: To that end, we have four reports published in Kidney International Reports from Wuhan, China, the Lombardy region of northern Italy, London, England and Paris, France (2-5) detailing their early experience with COVID-19 outbreaks affecting ESRD patients at outpatient dialysis facilities and leading to a large number resulting in hospitalization and, often, death, similar to our experience in New York City (6) . An additional area of concern is the high incidence of AKI in COVID-19 infected patients requiring hospital resources that strain not only ICU and ventilator capacity, but also renal replacement resources, including both conventional hemodialysis and continuous renal replacement resources.
    keywords: covid-19; patients; rate
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        item: #2269 of 7819
          id: cord-278984-0zof6s4d
      author: El-Tallawy, Salah N.
       title: Pain Management During the COVID-19 Pandemic
        date: 2020-08-25
       words: 6480
      flesch: 42
     summary: In light of the limited data available for COVID-19-related impact on chronic pain patients, this review explores the changes in the healthcare delivery system due to social distancing and safety precautions to provide the appropriate management of chronic pain patients during the COVID-19 pandemic. Understanding both the general problems facing chronic pain patients as well as specific problems in the COVID-19 era including deconditioning, increased mental health concerns, financial burdens, and potential for medication-induced immune-suppression is vital in the appropriate management of patients.
    keywords: care; chronic; covid-19; health; management; nsaids; opioid; pain; pandemic; patients; risk; treatment; use
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        item: #2270 of 7819
          id: cord-278993-w5aa0elj
      author: Tonetti, Tommaso
       title: Use of critical care resources during the first 2 weeks (February 24–March 8, 2020) of the Covid-19 outbreak in Italy
        date: 2020-10-12
       words: 3929
      flesch: 37
     summary: In patients treated outside the ICU, conventional O 2 therapy was applied in the 47.3% of the cases and non-invasive respiratory support (including NIV, CPAP and high-flow O 2 therapy) in the 52.7%, while 81.8% of ICU patients were intubated. Data regarding the impact of Covid-19 outbreak on the capacity of the health-care system to accomplish the need for ICU care are limited.
    keywords: beds; care; covid-19; data; icu; italy; non; outbreak; patients; resources; study; support
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        item: #2271 of 7819
          id: cord-278996-9lady4pc
      author: Callander, Denton
       title: Investigating the effects of COVID-19 on global male sex work populations: a longitudinal study of digital data
        date: 2020-06-26
       words: 4491
      flesch: 49
     summary: HIV prevention efforts have long promoted regular testing and status disclosure as important health initiatives among populations of sex workers and others 23 and the fact that male sex workers would seek to adapt these kinds of strategies to face the emerging threat of COVID-19 suggests their attention to and engagement in public health issues. Further, the free-text sections of male sex work profiles were analysed for any references to COVID-19; a content analysis using the techniques of thematic analysis was employed to define profile users' engagement with the virus and conduct frequency analyses.
    keywords: covid-19; data; health; male; profiles; risk; services; sex; workers
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        item: #2272 of 7819
          id: cord-279032-plj9kg42
      author: Jin, Kaifeng
       title: Re: Can the summer temperature drop COVID-19 cases?
        date: 2020-08-15
       words: 708
      flesch: 47
     summary: Except for Japan, COVID-19 in some other Asian countries with different temperature, like 45 Singapore, South Korea and China, in these countries, the government regulation is much more 46 powerful, the pandemic is almost under control, which showed environment temperature may not 47 be a vital factor for virus transmission. Low temperature of environment can 13 suppression the immune response, people in low temperature are more susceptible to be infected.
    keywords: covid-19; temperature
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        item: #2273 of 7819
          id: cord-279036-fwmb0rr7
      author: Monzani, Alice
       title: COVID-19 Pandemic: Perspective From Italian Pediatric Emergency Physicians
        date: 2020-06-22
       words: 2884
      flesch: 44
     summary: Translating COVID-19 pandemic surge theory to practice in the emergency department: how to expand structure Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults Coronavirus disease 2019 and children: what pediatric health care clinicians need to know Italian doctors call for protecting healthcare workers and boosting community surveillance during covid-19 outbreak Assessment of medical reserve corps volunteers' emergency response willingness using a threat-and efficacy-based model Qualitative Inquiry and Research Design: In this perspective, pediatricians should consider each patient as a potentially COVID-19-positive patient but should be able not to fixate only on COVID-19 disease, always bearing in mind more common differential diagnoses.
    keywords: care; covid-19; health; hospital; pandemic; ped
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        item: #2274 of 7819
          id: cord-279038-ocb1tlzp
      author: Quispe Flores, María Alejandra
       title: The COVID-19 pandemic in developing countries: A new opportunity to improve the monitoring of patients with diabetes mellitus
        date: 2020-09-22
       words: 576
      flesch: 40
     summary: The COVID-19 pandemic has taught us many lessons, including that diabetic patients have a higher risk of mortality and of developing severe course of disease 3 . key: cord-279038-ocb1tlzp authors: Quispe Flores, María Alejandra; Concepción Zavaleta, Marcio José; Plasencia Dueñas, Esteban Alberto; Lam, Mikaela Kcomt title: The COVID-19 pandemic in developing countries: A new opportunity to improve the monitoring of patients with diabetes mellitus date: 2020-09-22 journal: Diabetes Metab Syndr DOI: 10.1016/j.dsx.2020.09.023 sha: doc_id: 279038 cord_uid: ocb1tlzp nan The narrative review published by Macherera et al 1 has been of great interest to us, as it highlights the importance of establishing a personalized educational plan in patients with diabetes during the COVID-19 pandemic, based on preventive measures, medications, changes in lifestyle, self-monitoring of glucose, foot care and prevention of complications.
    keywords: diabetes; patients
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        item: #2275 of 7819
          id: cord-279046-wk4ja15k
      author: Pissurno, Neisa Santos Carvalho Alves
       title: Anosmia in the course of COVID-19: A case report
        date: 2020-07-31
       words: 2002
      flesch: 45
     summary: However, considering the safety, low cost, and ease of access to olfactory training, in addition to the lack of clinical trials or welldesigned studies, we believe olfactory training is a sound therapeutic option to be indicated in the clinical management of olfactory disorders in COVID-19 patients. [4] In conclusion, we believe that this case report will contribute to the increase in clinical suspicion of anosmia in COVID-19 patients, allowing for the isolation of the suspected patient, and consequently, aiding in controlling the pandemic.
    keywords: anosmia; covid-19; day; olfactory; patient
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        item: #2276 of 7819
          id: cord-279052-8hxdfdls
      author: Boet, S.
       title: Protocol for a multicentre randomized controlled trial of normobaric versus hyperbaric oxygen therapy for hypoxemic COVID-19 patients
        date: 2020-07-16
       words: 4134
      flesch: 41
     summary: 8, 17 Case series of HBOT treatment in hypoxemic COVID-19 patients from China, France and the United States show clinical benefits, e.g. reduced ICU admission and intubation rates. Approximately 15 to 20% of COVID-19 patients present with hypoxemic respiratory failure requiring oxygen supplementation.
    keywords: care; covid-19; hbot; hyperbaric; license; outcomes; oxygen; patients; preprint; trial
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        item: #2277 of 7819
          id: cord-279056-mmcoqtb5
      author: Seirafianpour, Farnoosh
       title: Cutaneous manifestations and considerations in COVID‐19 pandemic: A systematic review
        date: 2020-07-08
       words: 4662
      flesch: 35
     summary: There were several drug regimens used for treatment of COVID-19 patients, some of which could result in cutaneous side effects like presence of a new dermatoses or flare/aggravation of a previous dermatologic disorder. Hydroxychloroquine; Despite the inconclusive result over the implication of Anti-Malarial drugs; it is used widely for treating COVID-19 patients.
    keywords: case; covid-19; infection; lesions; like; pandemic; patients; psoriasis; rash; skin; treatment
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        item: #2278 of 7819
          id: cord-279106-3ffa9djf
      author: Syatila Ab Ghani, Nur
       title: Side chain similarity comparisons for integrated drug repositioning and potential toxicity assessments in epidemic response scenarios: the case for COVID-19
        date: 2020-10-21
       words: 6982
      flesch: 40
     summary: 33 34 3. Results and Discussion 35 In this study, sub-structural similarity searches and docking analyses were carried out to: (i) identify 36 potential targets and drug binding sites in SARS-CoV-2 proteins; (ii) identify off-targets for proposed drug 37 compounds for COVID-19; (iii) identify other approved drugs with similar structure to proposed drugs that 38 are potentially useful for COVID-19 treatment. In this work, the three-dimensional arrangements of amino acid side chains in known drug binding sites (substructures) were used to search for similarly arranged sites in SARS-CoV-2 protein structures in the Protein Data Bank for the potential repositioning of approved compounds.
    keywords: binding; compounds; cov-2; covid-19; docking; drug; pdbid; potential; protein; sars; similarity; sites; structures; target
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        item: #2279 of 7819
          id: cord-279110-u2k27jkn
      author: Alter, Scott M.
       title: The menacing assaults on science, FDA, CDC, and health of the US public
        date: 2020-10-10
       words: 1256
      flesch: 46
     summary: In contrast, US responses were delayed, fragmented, and failed to emphasise masking, social distancing, and crowd avoidance. The President recently proffered herd mentality to combat COVID-19 which would result in from two to six million avoidable deaths depending upon the timing and availability of an effective and safe vaccine applied to the majority of US citizens.
    keywords: covid-19; deaths; health; science
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        item: #2280 of 7819
          id: cord-279115-eyk8sxk7
      author: Cecconi, Maurizio
       title: Ten things we learned about COVID-19
        date: 2020-06-05
       words: 1622
      flesch: 46
     summary: Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Immunology of COVID-19: current state of the science Interpreting diagnostic tests for SARS-CoV-2 Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Endothelial cell infection and endotheliitis in COVID-19 Understanding pathophysiology of hemostasis disorders in critically ill patients with COVID-19 WHO (2020) WHO Immunity passports in the context of COVID-19 The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region Clinical characteristics of coronavirus disease 2019 in China Surviving sepsis campaign: guidelines on the management of critically ill adults with coronavirus disease 2019 (COVID-19) Developing Covid-19 vaccines at pandemic speed Managing ICU surge during the COVID-19 crisis: rapid guidelines Critical care utilization for the COVID-19 outbreak in Lombardy, Italy: early experience and forecast during an emergency response REMAP-CAP response to novel COVID-10 Evidence suggests that during COVID-19 T cells undergo functional exhaustion with lymphopenia, skewing towards a Th17 phenotype, inappropriate for antiviral immunity and suppression ( Fig. 1 )
    keywords: cells; covid-19; immunity; patients; sars
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        item: #2281 of 7819
          id: cord-279118-59e4sifb
      author: Hariyanto, Timotius Ivan
       title: Dyslipidemia is associated with severe coronavirus disease 2019 (COVID-19) infection
        date: 2020-08-01
       words: 1202
      flesch: 43
     summary: The title, abstract, and full text of all articles identified that matched the search criteria were assessed, and those reporting the rate of dyslipidemia in COVID-19 patients with a clinically validated definition of severe disease were included in this meta-analysis. [2] 2020 HDL-c levels predict the presence of pleural effusion and the clinical outcome of community-acquired pneumonia Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease Risk factors for disease progression in COVID-19 patients A Novel Scoring System for Prediction of Disease Severity in COVID-19 LICORN and the Lille COVID-19 and Obesity study group.
    keywords: covid-19; disease; dyslipidemia; patients
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        item: #2282 of 7819
          id: cord-279131-1unb0z79
      author: Buijsers, Baranca
       title: Beneficial non-anticoagulant mechanisms underlying heparin treatment of COVID-19 patients
        date: 2020-08-25
       words: 3995
      flesch: 23
     summary: The role of heparanase and the endothelial glycocalyx in the development of proteinuria Properties of the Glomerular barrier and mechanisms of Proteinuria Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19 Pulmonary Pathology of early-phase 2019 novel Coronavirus (COVID-19) Pneumonia in two patients with Lung Cancer Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Effect of Dexamethasone in hospitalized patients with COVID-19: preliminary report Incidence of thrombotic complications in critically ill ICU patients with COVID-19 ISTH interim guidance on recognition and management of coagulopathy in COVID-19 Low molecular weight heparins and their clinical applications Therapeutic use of heparin beyond anticoagulation Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Heparin therapy improving hypoxia in COVID-19 patients -a case series Association of treatment dose Anticoagulation with in-hospital survival among hospitalized patients with COVID-19 The versatile heparin in COVID-19 Inhibition of heparanase-mediated degradation of extracellular matrix heparan sulfate by non-anticoagulant heparin species The Glomerular Endothelium in Diabetic Nephropathy: Role of Heparanase: Pathophysiology and Clinical Aspects Endothelial glycocalyx dysfunction in disease: albuminuria and increased microvascular permeability Heparanase: roles in cell survival, extracellular matrix remodelling and the development of kidney disease The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis Increased plasma heparanase activity in COVID-19 patients Both UFH and NAH alleviate shedding of endothelial glycocalyx and coagulopathy in LPS-induced sepsis Dengue virus NS1 disrupts the Endothelial Glycocalyx, leading to Hyperpermeability Effect of unfractionated heparin on endothelial glycocalyx in a septic shock model Inhibition of inflammation induced shedding of the endothelial glycocalyx with low molecular weight heparin Heparanase Is Essential for the Development of Acute Experimental Glomerulonephritis Kinetic analysis and molecular modeling of the inhibition mechanism of roneparstat (SST0001) on human heparanase Structural requirements for inhibition of melanoma lung colonization by heparanase inhibiting species of heparin Chemically modified heparins as inhibitors of heparan sulfate specific endo-beta-glucuronidase (heparanase) of metastatic melanoma cells The anti-inflammatory effects of heparin and related compounds Anti-Inflammatory Effects of Heparin and Its Derivatives: a Systematic Review Protective effect of low molecular weight heparin on experimental colitis: role of neutrophil recruitment and TNF-alpha production Versatile role of heparanase in inflammation Glycosaminoglycans interact selectively with chemokines and modulate receptor binding and cellular responses Role of heparanase-driven inflammatory cascade in pathogenesis of diabetic nephropathy Heparanase augments insulin receptor signaling in breast carcinoma Soluble heparan sulfate fragments generated by heparanase trigger the release of pro-inflammatory cytokines through TLR-4 Macrophage activation by heparanase is mediated by TLR-2 and TLR-4 and associates with plaque progression Heparanase is essential for the development of diabetic nephropathy in mice Heparanase-2 protects from LPS-mediated endothelial injury by inhibiting TLR4 signalling COVID-19: consider cytokine storm syndromes and immunosuppression Regulation of interleukin-8 binding and function by heparin and alpha2-macroglobulin Binding of Interleukin-8 to Heparan Sulfate and Chondroitin Sulfate in Lung Tissue In-vitro suppression of IL-6 and IL-8 release from human pulmonary epithelial cells by non-anticoagulant fraction of enoxaparin Kinins and Cytokines in COVID-19: a comprehensive Pathophysiological approach Local bradykinin formation is controlled by glycosaminoglycans Clinical observations of low molecular weight heparin in relieving inflammation in COVID-19 patients: A retrospective cohort study.
    keywords: binding; cov-2; covid-19; endothelial; heparanase; heparin; hpse; lmwh; patients; sars
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        item: #2283 of 7819
          id: cord-279132-florvm7z
      author: K., Branimir
       title: From apparent to true – from frequency to distributions (II)
        date: 2020-08-17
       words: 2394
      flesch: 36
     summary: Bayesian approaches have also been used to assess the effects of social distancing measures on the dynamics of the epidemic in several affected countries. Feroze (7) used Bayesian structural time series models to investigate the pattern of SARS-CoV-2 spread in India, Brazil, USA, Russia, and the UK between March 1 and June 29, 2020 to assess the impact of mitigation measures and predict the dynamics of the epidemic over the next 30 days.
    keywords: approach; bayesian; cases; covid-19; data; epidemic; model
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        item: #2284 of 7819
          id: cord-279134-s6c7m94h
      author: Chen, Haiyang
       title: When cancer encounters COVID-19 in China: what have we suffered, experienced and learned
        date: 2020-05-16
       words: 4366
      flesch: 39
     summary: Here we share the experience of the medical management of cancer patients from China. In conclusion, although it is unclear whether cancer directly increases the incidence and risk of COVID-19 infection, it is certain that the prevalence of COVID-19 will have a significant impact on cancer patients both in terms of infection and receiving treatment for cancer.
    keywords: cancer; coronavirus; covid-19; epidemic; infection; lung; patients; risk; treatment
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        item: #2285 of 7819
          id: cord-279138-dmhphgp5
      author: Deek, Sarah A.
       title: Chronic Exposure to Air Pollution Implications on COVID-19 Severity
        date: 2020-09-28
       words: 1545
      flesch: 26
     summary: There is a need for a valid basis for the proactive identification of indicators of COVID-19 severity in air quality that allow for the implementation of systematic environmental improvements aimed at preventing COVID-19 mortality. There is a need for a valid basis for the proactive identification of indicators of COVID-19 severity in air quality that allow for the implementation of systematic environmental improvements aimed at preventing COVID-19 mortality.
    keywords: air; axis; covid-19; hpa
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        item: #2286 of 7819
          id: cord-279158-dsnniuo6
      author: Luo, Y.
       title: Low blood sodium increases risk and severity of COVID-19: a systematic review, meta-analysis and retrospective cohort study
        date: 2020-05-22
       words: 3906
      flesch: 38
     summary: In conclusion, we found that people with low serum sodium (hyponatremia) may be related to the susceptibility of SARS-CoV-2 infection and the development of severity of disease. key: cord-279158-dsnniuo6 authors: Luo, Y.; Li, Y.; Dai, J. title: Low blood sodium increases risk and severity of COVID-19: a systematic review, meta-analysis and retrospective cohort study date: 2020-05-22 journal: nan DOI: 10.1101/2020.05.18.20102509 sha: doc_id: 279158 cord_uid: dsnniuo6 Background Novel coronavirus (SARS-CoV-2) infects human lung tissue cells through angiotensin-converting enzyme-2 (ACE2), and the body sodium is an important factor for regulating the expression of ACE2.
    keywords: covid-19; medrxiv; patients; preprint; review; sars; serum; sodium; study
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        item: #2287 of 7819
          id: cord-279180-xad53zht
      author: Kumaravel, Santhosh Kumar
       title: Investigation on the impacts of COVID-19 quarantine on society and environment: Preventive measures and supportive technologies
        date: 2020-08-17
       words: 11414
      flesch: 49
     summary: The spread of COVID-19 disease was announced by the World Health Organization (WHO) as a public health emergency of international concern on 30th January 2020 (World Health Organisation 2020b). But it is reliable only in the first week of COVID-19 disease because after the first week it slowly starts to disappear on the throat and begins to multiply in the lungs.
    keywords: cases; china; coronavirus; covid-19; data; disease; et al; fig; health; human; intelligence; learning; lockdown; online; outbreak; pandemic; patients; people; quarantine; spread; technologies; transmission; world
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        item: #2288 of 7819
          id: cord-279197-cesemos0
      author: Block, Keith I.
       title: Integrative Cancer Therapies: Learning From COVID-19
        date: 2020-06-21
       words: 4120
      flesch: 31
     summary: In this journal, Yan et al 2 discussed the use of traditional Chinese medicine therapies with cancer patients afflicted with COVID-19. They also raised an alarm about therapies like massage and acupuncture that involve close contact with patients, and suggest they be rigidly considered or forbidden for cancer patients in endemic areas, with stronger personal protection provisions for both patients and therapists.
    keywords: cancer; covid-19; curcumin; intravenous; patients; quercetin; resveratrol; therapies; treatment; trials; vitamin
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        item: #2289 of 7819
          id: cord-279224-rwcvkhiy
      author: Kirmani, Salman
       title: Impact of COVID-19 pandemic on paediatric services at a referral centre in Pakistan: lessons from a low-income and middle-income country setting
        date: 2020-06-29
       words: 1072
      flesch: 40
     summary: Although most children are going to recover uneventfully from the infection, the impact of the disruption on the usual care of children such as school, sports and healthrelated activities including routine immunisations and preventative care visits is predicted to have severe consequences for the health of children in our part of the world. In a country where routine immunisation coverage was already poor prepandemic, a huge number of children have now missed and will further miss their vaccinations.
    keywords: care; children; covid-19
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        item: #2290 of 7819
          id: cord-279227-l6keimm5
      author: Li, Yuxi
       title: Clinical practice guidelines and experts’ consensuses of traditional Chinese herbal medicine for novel coronavirus (COVID-19): protocol of a systematic review
        date: 2020-08-03
       words: 2525
      flesch: 39
     summary: Clinical practice guidelines and experts’ consensuses of traditional Chinese herbal medicine for novel coronavirus (COVID-19): protocol of a systematic review date: 2020-08-03 journal: Updated versions of diagnosis and treatment guideline for novel coronavirus (COVID-19) patients have been issued, and traditional Chinese herbal medicine has been recommended as a treatment.
    keywords: clinical; coronavirus; covid-19; guidelines; medicine; patients; treatment
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        item: #2291 of 7819
          id: cord-279255-v861kk0i
      author: Dhama, Kuldeep
       title: Coronavirus Disease 2019–COVID-19
        date: 2020-06-24
       words: 23944
      flesch: 36
     summary: Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein Animal models for SARS and MERS coronaviruses Recent advances in the vaccine development against Middle East respiratory syndromecoronavirus Virology: SARS virus infection of cats and ferrets A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters Animal models and vaccines for SARS-CoV infection Infection with MERS-CoV causes lethal pneumonia in the common marmoset Vaccines for the prevention against the threat of MERS-CoV Molecular basis of coronavirus virulence and vaccine development Mice transgenic for human angiotensin-converting enzyme 2 provide a model for SARS coronavirus infection Genetically engineering a susceptible mouse model for MERS-CoV-induced acute respiratory distress syndrome Prospects for a MERS-CoV spike vaccine A mouse model for MERS coronavirus-induced acute respiratory distress syndrome Replicative capacity of MERS coronavirus in livestock cell lines Entry of human coronavirus NL63 into the cell China's response to a novel coronavirus stands in stark contrast to the 2002 SARS outbreak response Novel coronavirus is putting the whole world on alert Early epidemiological analysis of the coronavirus disease 2019 outbreak based on crowdsourced data: a population-level observational study Estimation of the transmission risk of the 2019-nCoV and its implication for public health interventions The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus The progress of 2019 novel coronavirus (2019-nCoV) event in China Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Response to the emerging novel coronavirus outbreak Potential for global spread of a novel coronavirus from China Novel coronavirus, poor quarantine, and the risk of pandemic Novel Coronavirus outbreak in Wuhan, China, 2020: intense surveillance is vital for preventing sustained transmission in new locations Risk for transportation of 2019 novel coronavirus disease from Wuhan to other cities in China Infections without borders: a new coronavirus in Wuhan, China An interactive web-based dashboard to track COVID-19 in real time Limiting spread of COVID-19 from cruise ships-lessons to be learnt from Japan Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records A case of 2019 novel coronavirus in a pregnant woman with preterm delivery Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study A pregnant woman with COVID-19 in Central America Latin American Network of Coronavirus Disease 2019-COVID-19 Research (LANCOVID-19). CEPI to fund three programmes to develop vaccines against the novel coronavirus, nCoV-2019 Moderna announces funding award from CEPI to accelerate development of messenger RNA (mRNA) vaccine against novel coronavirus Novel inhibitors of severe acute respiratory syndrome coronavirus entry that act by three distinct mechanisms Treatment with interferon-␣2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques Middle East respiratory syndrome coronavirus (MERS-CoV): challenges in identifying its source and controlling its spread COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics Potential antiviral therapeutics for 2019 novel coronavirus A novel coronavirus outbreak of global health concern Coronavirusesdrug discovery and therapeutic options Treatment with lopinavir/ritonavir or interferon-␤1b improves outcome of MERS-CoV infection in a nonhuman primate model of common Marmoset Treatment of Middle East respiratory syndrome with a combination of lopinavir-ritonavir and interferon-␤1b (MIRACLE trial): study protocol for a randomized controlled trial Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Breakthrough: chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein Characterization of novel monoclonal antibodies against MERScoronavirus spike protein Crossneutralization of SARS coronavirus-specific antibodies against bat SARS-like coronaviruses New coronavirus threat galvanizes scientists Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody Cell-based antiviral screening against coronaviruses: developing virus-specific and broad-spectrum inhibitors Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection Potential interventions for novel coronavirus in China: a systemic review Human transbodies that interfere with the functions of Ebola virus VP35 protein in genome replication and transcription and innate immune antagonism Inhibitors of RAS might be a good choice for the therapy of COVID-19 pneumonia Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture
    keywords: acute; animal; bat; cases; cell; china; control; coronavirus; cov-2; covid-19; covs; disease; drugs; health; host; human; infection; mers; ncov; novel; novel coronavirus; outbreak; patients; pneumonia; potential; protein; respiratory; risk; sars; sars coronavirus; spread; studies; study; syndrome; transmission; treatment; vaccine; viruses; wuhan
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        item: #2292 of 7819
          id: cord-279264-0bhgq3q9
      author: Bolarinwa, O. A.
       title: Adherence to COVID-19 pandemic prescribed recommendations, source of information and lockdown psychological impact of Nigeria social media users
        date: 2020-09-10
       words: 3721
      flesch: 47
     summary: Thus, this study examined the compliance level to COVID-19 prescribed recommendations, the psychological implications of lockdown, and the source of information on COVID-19 among Nigeria social media users. key: cord-279264-0bhgq3q9 authors: Bolarinwa, O. A.; Olagunju, O. S.; Babalola, T. title: Adherence to COVID-19 pandemic prescribed recommendations, source of information and lockdown psychological impact of Nigeria social media users date: 2020-09-10 journal: nan DOI: 10.1101/2020.09.09.20188482 sha: doc_id: 279264 cord_uid: 0bhgq3q9 Background: COVID-19 is a highly infectious viral disease that has spread to over one hundred and eight countries, including Nigeria.
    keywords: covid-19; health; license; medrxiv; preprint; respondents; study
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        item: #2293 of 7819
          id: cord-279290-wtnnlp4i
      author: Solorio-Pineda, Saúl
       title: Pituitary macroadenoma apoplexy in a severe acute respiratory syndrome-coronavirus-2-positive testing: Causal or casual?
        date: 2020-09-25
       words: 1375
      flesch: 44
     summary: Another study from the same group confirmed that ACD, including ischemic stroke, cerebral venous thrombosis, and cerebral hemorrhage, was typical in elderly COVID-19 patients. Surg Neurol Int DOI: 10.25259/sni_305_2020 sha: doc_id: 279290 cord_uid: wtnnlp4i BACKGROUND: In December 2019, in Wuhan, a new virus emerged, causing severe acute respiratory syndrome (SARS) secondary to infection by a type of coronavirus, causing coronavirus disease (COVID-19).
    keywords: covid-19; pituitary; sars
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        item: #2294 of 7819
          id: cord-279294-ruqednj6
      author: Lin, Dong D.
       title: Chemotherapy Treatment Modifications During the COVID-19 Outbreak at a Community Cancer Center in New York City
        date: 2020-08-14
       words: 3236
      flesch: 37
     summary: Oncologists had to consider the benefits of continuing or initiating cancer treatment, with many of these being myelosuppressive or immunosuppressive in nature, or both, against the risk of patients contracting the virus and developing severe complications. Medical oncology communities have developed treatment modifications to balance the risk of contracting the virus with the benefit of improving cancer-related outcomes.
    keywords: cancer; covid-19; disease; modifications; patients; providers; treatment
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        item: #2295 of 7819
          id: cord-279334-j0i9ozsz
      author: McCreary, Erin K
       title: Coronavirus Disease 2019 Treatment: A Review of Early and Emerging Options
        date: 2020-03-23
       words: 8289
      flesch: 41
     summary: The diagnosis and treatment guide of COVID-19 pneumonia caused by new coronavirus infection 7th Edition Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore Case of the index patient who caused tertiary transmission of COVID-19 infection in Korea: the application of lopinavir/ritonavir for the treatment of COVID-19 infected pneumonia monitored by quantitative RT-PCR The course of clinical diagnosis and treatment of a case infected with coronavirus disease 2019 Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 Pharmacokinetics of lopinavir/ritonavir crushed versus whole tablets in children Nitazoxanide, a new drug candidate for the treatment of Middle East respiratory syndrome coronavirus Effect of nitazoxanide in adults and adolescents with acute uncomplicated influenza: a double-blind, randomised, placebo-controlled, phase 2b/3 trial Efficacy and safety of nitazoxanide in addition to standard of care for the treatment of severe acute respiratory illness Tocilizumab for the treatment of chimeric antigen receptor T cell-induced cytokine release syndrome ASTCT consensus grading for cytokine release syndrome and neurologic toxicity associated with immune effector cells Cytokine release syndrome grade as a predictive marker for infections in patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with chimeric antigen receptor T cells FDA approval summary: tocilizumab for treatment of chimeric antigen receptor T cell-induced severe or life-threatening cytokine release syndrome Effective treatment of severe COVID-19 patients with tocilizumab SARS: systematic review of treatment effects Treatment of severe acute respiratory syndrome with glucosteroids: the Guangzhou experience Effects of early corticosteroid treatment on plasma SARS-associated coronavirus RNA concentrations in adult patients The use of corticosteroid as treatment in SARS was associated with adverse outcomes: a retrospective cohort study Corticosteroid therapy for critically ill patients with Middle East respiratory syndrome Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China On the use of corticosteroids for 2019-nCoV pneumonia Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area There are 4 clinical trials currently enrolling patients in the United States (Table 1) .
    keywords: activity; clinical; cov-2; covid-19; data; day; disease; hydroxychloroquine; lpv; patients; sars; therapy; treatment; use; vitro
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        item: #2296 of 7819
          id: cord-279345-dgdujcy3
      author: Sudhir, Amita
       title: A primary care alternative to a hospital-based approach to COVID-19 in India
        date: 2020-08-11
       words: 1757
      flesch: 40
     summary: Photo: use of an oxygen concentrator in primary health care (Basic Healthcare Services https://bhs.org.in). India, however, has the primary care infrastructure to offer a different solution, one that is based in the community, utilising the skills held by primary care providers, and the resources available to them.
    keywords: care; covid-19; hospital; oxygen; patients
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        item: #2297 of 7819
          id: cord-279356-s3iigb0j
      author: Leones, Louis Mervyn B
       title: Caring for the carers: safeguarding oncologists’ mental health in the time of COVID-19
        date: 2020-06-15
       words: 1497
      flesch: 40
     summary: Digital technologies provide a range of mental health interventions [8] . Daily encounters with patients who have chronic, terminal diseases present unique challenges to mental health, possibly leading to burnout
    keywords: covid-19; health; patients; support
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        item: #2298 of 7819
          id: cord-279363-4almssg6
      author: Crespo, Roland Mojica
       title: Pandemia COVID-19, la nueva emergencia sanitaria de preocupación internacional: una revisión
        date: 2020-05-16
       words: 5186
      flesch: 44
     summary: Estas estructuras están constituidas por complejos triméricos de la glicoproteína viral S (Spike) 5,14,15 . Concretamente la RNVE en su informe n°29 del día 7 de mayo enumera los principales síntomas presentados por el conjunto de la población española, hasta la fecha y a base de una muestra de 217,543 casos, de la siguiente manera: Entre estos hallazgos, es comúnmente observar la leucopenia y linfopenia, siendo esta última característica de COVID-19.
    keywords: 2019; 2020; casos; china; como; con; coronavirus; cov-2; covid-19; del; disease; enfermedad; entre; esta; este; han; hasta; health; infección; las; los; más; neumonía; novel; oms; pacientes; para; por; publicado; que; sars; son; una
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        item: #2299 of 7819
          id: cord-279395-qfb06csa
      author: Khan, Samea
       title: Is Pakistan prepared for the COVID‐19 epidemic? A questionnaire‐based survey
        date: 2020-04-10
       words: 1956
      flesch: 51
     summary: Characteristics of and public health responses to the Coronavirus disease 2019 outbreak in China Coronavirus disease 2019 (COVID-19): a perspective from China A new emerging zoonotic virus of concern: the 2019 novel Coronavirus (COVID-19) The outcome of this questionnaire suggests that Pakistan faces a unique challenge related to public health, which majorly is the peo- To avert the threat of an epidemic, it is significant that public knowledge, attitude, and behavior towards COVID-19 response is prompt.
    keywords: covid-19; health; infection; pakistan
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        item: #2300 of 7819
          id: cord-279396-qmixem8i
      author: Carter, Chris
       title: COVID-19 Disease: a critical care perspective
        date: 2020-06-01
       words: 5308
      flesch: 43
     summary: With the rapid expansion of critical care services, current policies and guidelines may be unrealistic due to the differing levels of staffing, the large influx of new staff not familiar with critical care and the dynamic and rapidly evolving COVID-19 situation. Ann Intensive Care Features, Evaluation and Treatment Coronavirus (COVID-19) Clinical guide for the management of critical care patients during the coronavirus pandemic An official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine clinical practice guideline: mechanical ventilation in adult patients with acute respiratory distress syndrome Lung recruitability in SARS-CoV-2 associated acute respiratory distress syndrome: a single-center, observational study Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury FDA advises patients on use of non-steroidal antiinflammatory drugs (NSAIDs) for COVID-19 Ibuprofen use and Coronavirus (COVID-19) Clinical management of persons admitted to hospital with suspected COVID-19 infection Godzilla in the corridor: The Ontario SARS crisis in historical perspective.
    keywords: care; covid-19; critical; disease; intensive; need; patients; risk; services; support; use
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        item: #2301 of 7819
          id: cord-279401-eehb5yny
      author: Haffejee, Sadiyya
       title: ‘When will I be free’: Lessons of COVID-19 for Child Protection in South Africa
        date: 2020-09-04
       words: 6644
      flesch: 44
     summary: One of the participants aptly summarises the range of emotions she is experienced during this period, many of which were echoed by other The image (Image 3) below by Child 2 and her explanation reflects the complex relationship that children in care have with parents. Speaking of her concern for her mum, [INSERT Image 3: Child 2 articulates her concern about her mother] In their concern, children and youth in care demonstrated an awareness of the 'I also think about school, when I will go back to school also if I will repeat a grade because I don't want to repeat.'
    keywords: access; africa; care; children; covid-19; cycc; lockdown; participants; social; south; study; support
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        item: #2302 of 7819
          id: cord-279405-1d6gznls
      author: Butt, Muhammad Hammad
       title: Dengue Fever and COVID‐19 Co‐Infection; A Threat to Public Health for Co‐epidemic in Pakistan
        date: 2020-08-27
       words: 1074
      flesch: 47
     summary: Recently, National Institute of Health (NIH) in Pakistan issued 'High Alert' for dengue viral infection (DVI) as monsoon season (July -December) is considered a vulnerable period for dengue spread [2] . Skin rash, a cardinal feature of DVI, has also been observed in COVID-19 patients [6] .
    keywords: covid-19; dengue; pakistan; patients
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        item: #2303 of 7819
          id: cord-279415-s823mver
      author: Guo, Xiaodong
       title: Survey of COVID-19 Disease Among Orthopaedic Surgeons in Wuhan, People’s Republic of China
        date: 2020-04-23
       words: 3431
      flesch: 49
     summary: Orthopaedic surgeons are at risk during the COVID-19 pandemic. Orthopaedic surgeons have to be more vigilant and take more precautions to avoid infection with COVID-19.
    keywords: control; covid-19; health; infection; orthopaedic; surgeons; wuhan
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        item: #2304 of 7819
          id: cord-279428-5t2qi2on
      author: Mahmoudi, Morteza
       title: COVID-19 pandemic may fuel academic bullying
        date: 2020-06-27
       words: 1188
      flesch: 28
     summary: The outcomes suggest that COVID-19 related papers are being considered as fast-tack by journals with processing times significantly shorter than the non-COVID papers (i.e., average manuscript processing days, from submission to acceptance, for Nature and Science for non-COVID papers are 276 and 208 days, respectively. This concern might be relevant, as we witness a huge number of COVID-19 related published papers from non-virology experts since January 2020.
    keywords: behaviors; covid-19; research
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        item: #2305 of 7819
          id: cord-279435-ffgd2ets
      author: ALBalawi, Hani B
       title: COVID-19: Precautionary Guidelines for Ophthalmologists
        date: 2020-06-25
       words: 3188
      flesch: 46
     summary: Highrisk or COVID-19 positive patients with urgent ophthalmic problems can be seen but after following local hospital guidelines and precautions for treating patients with COVID-19 or that of the Centers for Disease Control and Prevention (CDC) such as using an N95 mask, eye protection, and gowns ( Figure 1 ) In 99 patients with COVID-19 virus infection, chest pain, confusion, and nausea-vomiting were noted in addition to previous findings [15] .
    keywords: contact; coronavirus; covid-19; health; human; infection; ophthalmologists; patients; risk
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        item: #2306 of 7819
          id: cord-279443-2e4gz2bo
      author: Khan, Suliman
       title: Transmission of SARS-CoV-2, Required Developments in Research and Associated Public Health Concerns
        date: 2020-06-09
       words: 4944
      flesch: 36
     summary: The proximal origin of SARS-CoV-2 Emergence of a novel coronavirus, severe acute respiratory syndrome coronavirus 2: biology and therapeutic options Development of animal models against emerging coronaviruses: from SARS to MERS coronavirus Interim Infection Prevention and Control Recommendations for Patients with Suspected or Confirmed Coronavirus Disease 2019 (COVID-19) in Healthcare Settings Advice for the Public Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients Impact of PD-1 blockade on severity of COVID-19 in patients with lung cancers COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients People Who Are at Higher Risk for Severe Illness (Older Adults) Association of COVID-19 infection with pregnancy outcomes in healthcare workers and general women Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn Team 2019-nCoV CDC response. Until now, researchers have unveiled some of the important biological and clinical features for COVID-19 infection, including the characterization of the whole genome (8) and spike glycoproteins (9) , investigation of clinical features and evaluation of different broad-spectrum antiviral drugs in combination with either antibacterial, antimalarial and/or traditional Chinese medicines (10) .
    keywords: coronavirus; cov-2; covid-19; disease; human; individuals; infection; novel; patients; sars; transmission
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        item: #2307 of 7819
          id: cord-279456-oouylyx9
      author: Henchi, Sonia
       title: First COVID-19 sub-intensive respiratory unit in Europe: the Italian experience
        date: 2020-06-23
       words: 1504
      flesch: 42
     summary: In UTISIR were admitted patients testing positive to SARS-CoV-2 throat swab with phenotype 3,4,5, ICU patients weaned from intubation, with tracheostomy and transferred from other low-intensity care departments of the hospital, when appropriated. In this paper, we describe how the first Sub-intensive Respiratory Unit in Europe completely dedicated to COVID-19 patients was organized and managed in our hospital.
    keywords: covid-19; cpap; icu; patients; unit; utisir
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        item: #2308 of 7819
          id: cord-279468-xe84s5i4
      author: Fares, Elie
       title: DIFFUSE ALVEOLAR HEMORRHAGE AS A CONSEQUENCE OF MICROSCOPIC POLYANGIITIS DUE TO COVID-19
        date: 2020-10-31
       words: 386
      flesch: 37
     summary: TO COVID-19 date: 2020-10-31 journal: Chest DOI: 10.1016/j.chest.2020.08.722 sha: doc_id: 279468 cord_uid: xe84s5i4 nan Other admission laboratory values were significant for a creatinine of 4.9 mg/dL (baseline: 0.8mg/dL), hemoglobin of 8 g/dL (baseline: 11.8g/dL), ferritin 569 ng/mL, D-dimer 3.18 ug/mL, CRP 62.8 mg/L, ESR 118 mm/hr. A CT scan showed extensive bilateral consolidations with air bronchograms that were not typical for a COVID-19 pneumonia (Image 1) except in the apices where these dense consolidations had a peripheral pattern.
    keywords: covid-19
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        item: #2309 of 7819
          id: cord-279480-nqp1pc9v
      author: Ring, Laurence E.
       title: What Obstetricians should know about Obstetric Anesthesia during the COVID-19 pandemic
        date: 2020-08-26
       words: 2785
      flesch: 31
     summary: A randomized trial of phenylephrine infusion versus bolus dosing for nausea and vomiting during Cesarean delivery in obese women Antiemetics added to phenylephrine infusion during cesarean delivery: a randomized controlled trial Spinal-induced hypotension: Incidence, mechanisms, prophylaxis, and management: Summarizing 20 years of research Uterine Exteriorization Compared With In Situ Repair of Hysterotomy After Cesarean Delivery: A Randomized Controlled Trial Uterine exteriorization compared with in situ repair for Cesarean delivery: a systematic review and meta-analysis Compared to standard care in noninfected patients, the anesthesiologist may be more likely to replace a questionably functional epidural catheter in COVID-19 infected patients, in hopes to avoid urgent situations that may increase the odds for patient adverse outcomes (e.g. accidental dural puncture during a replacement of epidural catheter, or general anesthesia if urgent cesarean delivery) or avoidable exposures for healthcare providers (rushed replacement of neuraxial analgesia/anesthesia or general anesthesia in the operating room).
    keywords: analgesia; anesthesia; cesarean; covid-19; delivery; labor; neuraxial
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        item: #2310 of 7819
          id: cord-279485-hajrnur1
      author: Pope, Janet E.
       title: What Does the COVID-19 Pandemic Mean for Rheumatology Patients?
        date: 2020-04-30
       words: 1397
      flesch: 53
     summary: Preliminarily, articles seem to suggest that patients with rheumatic diseases may not have more infections from SARS-CoV-2 and similar outcomes to age and gender matched patients, but fear of rheumatic medications increasing their risk, drug shortages, and work exposure all are concerns for patients. The long term effects of the pandemic in patients with rheumatic diseases will not be known until much later and likely include stressors flaring disease (fear, illness, job loss, social isolation), post-traumatic stress, flaring due to stopping medications, less physician visits with subsequent under-treatment, and increases in chronic concomitant fatigue, pain, fibromyalgia.
    keywords: covid-19; diseases; patients; risk
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        item: #2311 of 7819
          id: cord-279488-oc0edgd2
      author: Nguyen, Trieu
       title: 2019 Novel Coronavirus Disease (COVID-19): Paving the Road for Rapid Detection and Point-of-Care Diagnostics
        date: 2020-03-14
       words: 3243
      flesch: 52
     summary: For virus detection, for example, influenza [40] or human norovirus, LAMP assay offers one-step detection [38] (Veterinary, Portable, Onsite Detection), in the VIVALDI project, detection time can be less than 1 h.
    keywords: coronavirus; covid-19; detection; disease; novel; outbreak; pcr
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        item: #2312 of 7819
          id: cord-279511-s9h1jzzs
      author: Di Stefano, Vincenzo
       title: Significant reduction of physical activity in patients with neuromuscular disease during COVID-19 pandemic: the long-term consequences of quarantine
        date: 2020-07-13
       words: 4163
      flesch: 43
     summary: Finally, we found a correlation between SF-12 scores and the entity of the reduction of PA level during quarantine, thus confirming a relevant association with the quality of life in NMD. In the present cross-sectional study we aimed to explore the impact of COVID-19 lockdown on PA in NMD and to quantify the expected reduction of PA levels, as well its effect on the quality of life.
    keywords: activities; covid-19; intensity; level; patients; quarantine; walking
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        item: #2313 of 7819
          id: cord-279513-m4jdc8ua
      author: Onesti, Concetta Elisa
       title: Oncological care organisation during COVID-19 outbreak
        date: 2020-08-26
       words: 4161
      flesch: 41
     summary: A novel coronavirus from patients with pneumonia in China Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding The proximal origin of SARS-CoV-2 COVID-19 data Repository by the center for systems science and engineering (CSSE) at Johns Hopkins University SARS-CoV-2 transmission in patients with cancer at a tertiary care hospital in Wuhan, China Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Case-Fatality rate and characteristics of patients dying in relation to COVID-19 in Italy European Centre for Disease Prevention and Control -Covid-19 pandemic Cancer care during the spread of coronavirus disease 2019 (COVID-19) in Italy: young oncologists' perspective Radiation therapy during the coronavirus disease 2019 (covid-19) pandemic in Italy: a view of the nation's young oncologists COVID19 Prevention & Care A Cancer Specific Guideline Cancer Care Delivery Challenges Amidst Coronavirus Disease -19 (COVID-19) Outbreak: Specific Precautions for Cancer Patients and Cancer Care Providers to Prevent Spread Practice recommendations for risk-adapted head and neck cancer radiation therapy during the COVID-19 pandemic: an ASTRO-ESTRO consensus statement Practice recommendations for lung cancer radiotherapy during the COVID-19 pandemic: an ESTRO-ASTRO consensus statement Management of lung nodules and lung cancer screening during the COVID-19 pandemic: chest expert panel report Neuro-Oncology management during the COVID-19 pandemic with a focus on who grade III and IV gliomas A practical approach to the management of cancer patients during the novel coronavirus disease 2019 (COVID-19) pandemic: an international Collaborative group Managing COVID-19 in the oncology clinic and avoiding the distraction effect Summary of international recommendations in 23 languages for patients with cancer during the COVID-19 pandemic Active and effective measures for the care of patients with cancer during the COVID-19 spread in China Incorporating telemedicine as part of COVID-19 outbreak response systems Dynamic profile of RT-PCR findings from 301 COVID-19 patients in Wuhan, China: a descriptive study SARS-CoV-2 viral load in upper respiratory specimens of infected patients Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens Sensitivity of chest CT for COVID-19: comparison to RT-PCR Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Correlation of chest CT and RT-PCR testing for coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Performance of VivaDiag COVID-19 IgM/IgG rapid test is inadequate for diagnosis of COVID-19 in acute patients referring to emergency room department Antibody responses to SARS-CoV-2 in patients with COVID-19 Lower detection rates of SARS-COV2 antibodies in cancer patients versus health care workers after symptomatic COVID-19 Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Viral dynamics in mild and severe cases of COVID-19 Call for ensuring cancer care continuity during COVID-19 pandemic Provenance and peer review Not commissioned; externally peer reviewed. This, however, has often resulted in a lack of resources for routine patient care.
    keywords: cancer; care; cases; centres; covid-19; hospital; pandemic; patients; risk
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        item: #2314 of 7819
          id: cord-279525-76iq0gcy
      author: Kewan, Tariq
       title: COVID‐19 patient with immune thrombocytopenic purpura
        date: 2020-08-12
       words: 374
      flesch: 50
     summary: key: cord-279525-76iq0gcy authors: Kewan, Tariq; Almhana, Farah; Schwartzman, Larisa; Daw, Hamed; Haddad, Abdo title: COVID‐19 patient with immune thrombocytopenic purpura date: 2020-08-12 journal: Laboratory tests on admission showed a normal white cell count, hemoglobin (Hb) of 12.0 g/d, and platelet count (175 000/mm 3 ).
    keywords: covid-19; patient
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        item: #2315 of 7819
          id: cord-279529-m7c6270u
      author: Abrams, Hannah R.
       title: Characteristics of U.S. Nursing Homes with COVID‐19 Cases
        date: 2020-06-02
       words: 1226
      flesch: 47
     summary: These data nationally are limited by current tracking and reporting capacity, as well as the lack of a national system for reporting nursing home COVID-19 cases. Our finding that facilities with a high percentage of African American residents are more likely to have COVID-19 cases echoes disparities in the pandemic at large and indicates a critical health disparity to be addressed in the response to COVID-19 nursing home outbreaks.
    keywords: cases; covid-19; nursing
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        item: #2316 of 7819
          id: cord-279534-klqg8wnh
      author: Mari, Giulio M.
       title: A 10-step guide to convert a surgical unit into a COVID-19 unit during the COVID-19 pandemic
        date: 2020-04-27
       words: 798
      flesch: 58
     summary: The surgical team must be then divided in two sub-teams: a dedicated COVID-19 team working in the COVID-19 units, and a surgical clean team dedicated to the surgical procedures working in COVID-19 free surgical units (7) . Dedicated technical staff had to create a clean-dirty path for medical and nursing staff and for the COVID-19 patients within the unit.
    keywords: covid-19; unit
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        item: #2317 of 7819
          id: cord-279550-7u2hksxm
      author: Wang, Kai
       title: Longitudinal dynamics of the neutralizing antibody response to SARS-CoV-2 infection
        date: 2020-08-03
       words: 2671
      flesch: 47
     summary: Moreover, a SARS-CoV A c c e p t e d M a n u s c r i p t 14 antigen-specific memory B cell response was not detectable in recovered SARS patients at 6-years after disease onset, whereas SARS-CoV-specific memory T cells persisted in recovered SARS patients. NAb titers increased over time in parallel with the rise in IgG antibody levels, correlating well at week 3 (r = 0·41, p & 0·05).
    keywords: cov-2; covid-19; levels; nab; nabs; patients; sars
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        item: #2318 of 7819
          id: cord-279559-mob8dbcr
      author: Coleman, Carl H.
       title: Equitably Sharing the Benefits and Burdens of Research: Covid‐19 Raises the Stakes
        date: 2020-05-14
       words: 1378
      flesch: 36
     summary: The question of where Covid-19 clinical trials will be conducted is relevant to both the burdens and benefits of research. For example, in the United States, there is substantial evidence that African American and Hispanic and Latinx patients are underrepresented among clinical trial participants.
    keywords: covid-19; health; research; trials
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        item: #2319 of 7819
          id: cord-279561-p6wh7jja
      author: Karim, Jamila S.
       title: Bolstering the surgical response to COVID‐19: how virtual technology will save lives and safeguard surgical practice
        date: 2020-04-29
       words: 803
      flesch: 39
     summary: Non-urgent procedures are being postponed indefinitely as bed space and intensive care facilities typically dedicated to surgical patients are reallocated to those with COVID-19. The authors of COVID-19 and Urology: A Comprehensive Review of Literature have written a perceptive article which clearly outlines the complex challenges that COVID-19 is posing to urological surgeons and, indeed, the global surgical community at-large.
    keywords: covid-19; surgeons
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        item: #2320 of 7819
          id: cord-279566-27wmd3g5
      author: Shi, Li
       title: Is neutrophilia associated with mortality in COVID‐19 patients? A meta‐analysis and meta‐regression
        date: 2020-07-24
       words: 742
      flesch: 34
     summary: Considering the inherent differences among studies, we calculated the pooled standardized mean difference (SMD) and corresponding 95% confidence interval (CI) for continuous variables by using random-effects model to evaluate the relationship between changes in neutrophil counts and mortality of COVID-19 patients. A meta‐analysis and meta‐regression date: 2020-07-24 journal: Int J Lab Hematol DOI: 10.1111/ijlh.13298 sha: doc_id: 279566 cord_uid: 27wmd3g5 nan view, and studies with overlapping data were excluded.
    keywords: covid-19; patients
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        item: #2321 of 7819
          id: cord-279571-chiadufa
      author: Cui, Xiaoyang
       title: Acute Kidney Injury in Patients with the Coronavirus Disease 2019: A Multicenter Study
        date: 2020-07-24
       words: 3931
      flesch: 50
     summary: Our findings show that admission SOFA score was an independent risk factor for AKI in COVID-19 patients, and patients with AKI had higher in-hospital mortality. The clinical symptoms of COVID-19 patients include fever, cough, and fatigue, and a small population of patients exhibit gastrointestinal symptoms.
    keywords: admission; aki; covid-19; early; fluid; late; patients; study
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        item: #2322 of 7819
          id: cord-279629-t1xjy12y
      author: Nazneen Akhand, Mst Rubaiat
       title: Genome based Evolutionary study of SARS-CoV-2 towards the Prediction of Epitope Based Chimeric Vaccine
        date: 2020-04-15
       words: 6731
      flesch: 37
     summary: ( Figure 10E ) indicated low chance of deformation of vaccine protein V3. Protein sequence of the spike, envelope, membrane and nucleocapsid were also retrieved from the corresponding genome sequences found in NCBI (Supplementary File 1).
    keywords: analysis; cell; coronavirus; covid-19; different; epitopes; et al; figure; novel; prediction; protein; sars; server; spike; study; table; vaccine
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        item: #2323 of 7819
          id: cord-279631-1hlrx7o4
      author: Huang, Yan‐Mei
       title: CHINA'S OLDEST CORONAVIRUS SURVIVORS
        date: 2020-04-08
       words: 1548
      flesch: 50
     summary: The isolation of nursing home patients has led to some negative consequences. Nursing home patients in particular have higher rates of dementia, delirium, and behavioral issues 8 that require greater nursing care, which is challenging in isolation facilities, especially in the context of a global pandemic.
    keywords: coronavirus; covid-19; nursing; patients; year
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        item: #2324 of 7819
          id: cord-279645-gwxu6dz2
      author: Montoya-Barthelemy, Andre
       title: COVID-19 and the Correctional Environment: The American Prison as a Focal Point for Public Health
        date: 2020-04-17
       words: 1762
      flesch: 33
     summary: More than 500,000 correctional officers and correctional medical staff work in this environment. Landlords may refuse housing to recently released prisoners on concerns of contagion, and much-needed social services and medical management are heavily burdened. Already facing discrimination in hiring, released prisoners will be seeking work at a time when the unemployment rates are hitting historic levels.
    keywords: community; covid-19; disease; health; prisoners
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        item: #2325 of 7819
          id: cord-279648-ft62m7zz
      author: Raisi-Estabragh, Z.
       title: NON-WHITE ETHNICITY, MALE SEX, AND HIGHER BODY MASS INDEX, BUT NOT MEDICATIONS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM ARE ASSOCIATED WITH CORONAVIRUS DISEASE 2019 (COVID-19) HOSPITALISATION: REVIEW OF THE FIRST 669 CASES FROM THE UK BIOBANK
        date: 2020-05-15
       words: 3579
      flesch: 39
     summary: In this analysis of the first release of 1,474 COVID-19 test results from the UKB, non-white ethnicity, male sex, greater BMI, diabetes, hypertension, prior MI and smoking were independently associated with COVID-19 positive test in comparison to rest of the cohort (tested negatives plus untested). In our study, ethnicity appeared to have specific association with COVID-19 positive status that appeared independent from the often-quoted confounders of cardiovascular and metabolic morbidity that are known to be higher in prevalence in BME cohorts 15 .
    keywords: cohort; covid-19; ethnicity; license; medrxiv; perpetuity; preprint
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        item: #2326 of 7819
          id: cord-279649-wllc0gl5
      author: Kent, Katherine
       title: Prevalence and Socio-Demographic Predictors of Food Insecurity in Australia during the COVID-19 Pandemic
        date: 2020-09-02
       words: 6924
      flesch: 38
     summary: An affirmative response to this question would indicate household food insecurity with other scales, including the single-item measure of food insecurity which is commonly used in Australian studies of food insecurity [9] . Food insecurity has worsened within economically vulnerable populations under COVID-19 conditions, with a loss of income in already low-income households putting individuals at even higher risk of food insecurity.
    keywords: covid-19; food; food insecurity; household; income; insecurity; odds; pandemic; respondents; study
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        item: #2327 of 7819
          id: cord-279667-ikfduu2k
      author: Ronnje, Louise
       title: Complicated COVID-19 in pregnancy: a case report with severe liver and coagulation dysfunction promptly improved by delivery
        date: 2020-09-04
       words: 3366
      flesch: 45
     summary: [19] found that elevated levels of IL-6 were associated with a significantly increased risk of mortality in COVID-19 patients but in this case the inflammatory markers (and liver enzyme tests) decreased significantly after the Caesarean section. Atypical presentation of HELLP could not be ruled out and the importance of a multidisciplinary team in the treatment and management of severe COVID-19 during pregnancy is critical for positive patient outcome.
    keywords: case; clinical; coronavirus; covid-19; day; infection; liver; patient; pregnancy
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        item: #2328 of 7819
          id: cord-279713-97a86bor
      author: Negrini, Stefano
       title: Feasibility and acceptability of telemedicine to substitute outpatient rehabilitation services in the COVID-19 emergency in Italy: an observational everyday clinical-life study
        date: 2020-08-12
       words: 2168
      flesch: 48
     summary: key: cord-279713-97a86bor authors: Negrini, Stefano; Donzelli, Sabrina; Negrini, Alberto; Negrini, Alessandra; Romano, Michele; Zaina, Fabio title: Feasibility and acceptability of telemedicine to substitute outpatient rehabilitation services in the COVID-19 emergency in Italy: an observational everyday clinical-life study date: 2020-08-12 journal: Arch Phys Med Rehabil DOI: 10.1016/j.apmr.2020.08.001 sha: doc_id: 279713 cord_uid: 97a86bor Abstract Objective To investigate the feasibility and acceptability of telemedicine as a substitute of outpatient services in emergency situations like by the sudden surge of the COVID-19 pandemic in Italy. We found a rapid decrease (-39%) of outpatient services from CONTROL to COVID phase (R2=0.85), partially recovered in TELEMED for telephysiotherapy (from -37% to -21%; p<0.05), and stabilised for teleconsultation (from -55% to -60%) interventions.
    keywords: consultations; covid-19; face; services; telemedicine
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        item: #2329 of 7819
          id: cord-279719-z0wuajpx
      author: Martin-Fumadó, Carles
       title: Medico-legal and ethical considerations on resource limitation and clinical decisions during the COVID-19 pandemic
        date: 2020-07-15
       words: 4958
      flesch: 37
     summary: 12 Over and above specific scenarios, such as the emergency department, healthcare systems always set priorities in medical care, and this involves macroassignation processes as well as the microassignation of medical resources. Determining the scopes and limits of what it is fair to demand depends on the way in which the right to medical care is defined and specified, together with the creation of criteria for the distribution of medical resources.
    keywords: care; covid-19; decision; justice; making; pandemic; patients; rationing; resources
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        item: #2330 of 7819
          id: cord-279735-3sq7m3qw
      author: Yoshihiro, Noda
       title: Socioeconomical Transformation and Mental Health Impact by the COVID-19's ultimate VUCA Era: Toward the New Normal, the New Japan, and the New World
        date: 2020-06-22
       words: 933
      flesch: 37
     summary: The only way for humanity's wisdom to confront this challenge is the digital transformation of public mental health and psychiatry through the use of IT. Specifically, a certain number of people may have mental health problems due to the techno-stress (La Torre et al., 2019) associated with the rapid changes in social systems in the process of digitization of the social infrastructure.
    keywords: covid-19; health; pandemic
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        item: #2331 of 7819
          id: cord-279736-udsbcqfs
      author: Abdalkader, Mohamad
       title: Roadmap for Resuming Elective Neuroendovascular Procedures Following the First COVID-19 Surge
        date: 2020-07-27
       words: 1888
      flesch: 21
     summary: key: cord-279736-udsbcqfs authors: Abdalkader, Mohamad; Sathya, Anvitha; Malek, Adel M.; Fifi, Johanna T.; Norbash, Alexander M.; Wakhloo, Ajay K.; Nguyen, Thanh N. title: Roadmap for Resuming Elective Neuroendovascular Procedures Following the First COVID-19 Surge date: 2020-07-27 journal: J Stroke Cerebrovasc Dis DOI: 10.1016/j.jstrokecerebrovasdis.2020.105177 sha: doc_id: 279736 cord_uid: udsbcqfs The COVID-19 pandemic led to prioritizing high-acuity care of COVID-19 patients, while deferring non-emergent neurointerventional procedures worldwide in order to both limit contagion and add capacity for the anticipated COVID-19 surge. More specifically, health care resources, health care workers, and personal protective equipment (PPE) were all reorganized to ensure availability for the anticipated care of COVID-19 patients.
    keywords: care; covid-19; patients; procedure; risk
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        item: #2332 of 7819
          id: cord-279750-if9vphb2
      author: Savić, Dragan
       title: Ruptured cerebral pseudoaneurysm in an adolescent as an early onset of COVID-19 infection: case report
        date: 2020-07-27
       words: 2048
      flesch: 46
     summary: We speculate that the formation and the rupture of cerebral pseudoaneurysm could be linked to COVID-19 infection. As far as we know, this is the first reported case of an adolescent with ruptured cerebral pseudoaneurysm as the initial presentation of COVID-19 infection.
    keywords: brain; cerebral; covid-19; infection; pseudoaneurysm; sars
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        item: #2333 of 7819
          id: cord-279779-kp6ik8qb
      author: Blair, A.
       title: Identifying gaps in COVID-19 health equity data reporting in Canada using a scorecard approach
        date: 2020-09-25
       words: 3982
      flesch: 43
     summary: The objective of this study was to perform an environmental scan of COVID-19 data reporting across Canadian provinces and territories and to assess health equity-focused reporting using a scorecard approach. However, given that provincial and territorial rather than federal public health authorities are the primary entities collecting and reporting on health data in Canada, public-facing output on local-or social marker-disaggregated data can vary across Canadian jurisdictions.
    keywords: cases; covid-19; data; health; license; medrxiv; preprint; reporting
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        item: #2334 of 7819
          id: cord-279828-es498qul
      author: Boulle, Andrew
       title: Risk factors for COVID-19 death in a population cohort study from the Western Cape Province, South Africa
        date: 2020-08-29
       words: 3653
      flesch: 35
     summary: COVID-19 in patients with HIV: clinical case series Clinical features and outcomes of HIV patients with coronavirus disease 2019 COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients COVID-19 in patients with HIV A Case Series of Five People Living with HIV Hospitalized with COVID-19 in Clinical characteristics and outcomes in people living with HIV hospitalized for COVID-19 Description of COVID-19 in HIV-infected individuals: a single-centre, prospective cohort OpenSAFELY: factors associated with COVID-19 death in 17 million patients Dysregulation of immune response in patients with COVID-19 in Wuhan, China Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study Could HIV infection alter the clinical course of SARS-CoV-2 infection? We also calculated the standardized mortality ratio (SMR) of the actual number of COVID-19 deaths in PLWH vs. the number that would be expected if PLWH had the same risk of COVID-19 death as HIV-negative people of the same age and sex.
    keywords: art; cases; covid-19; covid-19 death; death; hiv; mortality; patients; plwh; risk; sector; tuberculosis
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        item: #2335 of 7819
          id: cord-279846-g0ro8pbb
      author: Terrigno, Vittorio R
       title: Right Atrial Thrombus in a Patient With COVID-19
        date: 2020-07-28
       words: 1058
      flesch: 42
     summary: This may be beneficial in patients with COVID-19 who require prone positioning and frequent neurological checks as well as for COVID-19 patients who are at higher risk when receiving thrombolytic therapy. Due to hospital protocol during the COVID-19 pandemic and the family's wish, Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Incidence of thrombotic complications in critically ill ICU patients with COVID-19 COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up: JACC State-ofthe-Art Review In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work.
    keywords: anticoagulation; covid-19; patients
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        item: #2336 of 7819
          id: cord-279875-jxnszm5k
      author: Wang, Wan-Ying
       title: Contribution of traditional Chinese medicine to the treatment of COVID-19
        date: 2020-07-07
       words: 2047
      flesch: 35
     summary: Coronavirus disease (COVID-19) Situation Report -125 Traditional Chinese medicine has a definite effect on mild cases and can also assist in the treatment of severe cases of COVID-19 Treatise on Acute Epidemic Febrile Diseases Inhibitory effects of flavonoids extracted from licorice on lipopolysaccharide-induced acute pulmonary inflammation in mice Feiyan no.1 prescription used in many designated treatment hospitals in Guangdong TCM widely used in COVID-19 patient treatment, yielding good results Pathological findings of COVID-19 associated with acute respiratory distress syndrome Combining TCM,Western medicine effective against virus Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Glycyrrhizin administration ameliorates Streptococcus aureus-induced acute lung injury Protective effect of Amygdalin on LPS-induced acute lung injury by inhibiting NF-κB and NLRP3 signaling pathways Academician Tong Xiaolin: In a clinical experiment (first batch of clinical data involving TCM treatment) of 52 confirmed cases, of which 34 cases were treated with TCM-integrated therapy with chemical.
    keywords: cases; covid-19; patients; tcm; therapy; treatment
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        item: #2337 of 7819
          id: cord-279891-v71rysnw
      author: Karampekos, George
       title: Differences between fellows and fellowship program directors in their perception of the impact of the COVID-19 pandemic on gastroenterology training: results from a nationwide survey in Greece
        date: 2020-10-12
       words: 3156
      flesch: 32
     summary: To conclude, Greek gastroenterology fellows are convinced that the COVID-19 outbreak will have a negative impact on their training, while training program directors are less concerned. Dig Liver Dis The impact of COVID-19 on endoscopic training The impact of COVID-19 on gastrointestinal endoscopy training in the United Kingdom Do breaks in gastroenterology fellow endoscopy training result in a decrement in competency in colonoscopy? Status of competency-based medical education in endoscopy training: a nationwide survey of US ACGME-accredited gastroenterology training programs Factors associated with residents' satisfaction with their training as specialists COVID-19 and endoscopy training Restarting gastrointestinal endoscopy in the deceleration and early recovery phases of COVID-19 pandemic: Guidance from the British Society of Gastroenterology COVID-19) outbreak: what the department of endoscopy should know The challenges of continuing medical education in a pandemic era COVID-19 pandemic through the lens of a gastroenterology fellow: looking for the silver lining The authors would like to thank all participants for their contribution to the study.
    keywords: covid-19; directors; fellows; impact; program; training
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        item: #2338 of 7819
          id: cord-279904-hfnlp6qv
      author: Hoedl, M.
       title: COVID-19 among nursing staff: Settings and regional differences
        date: 2020-08-17
       words: 3769
      flesch: 52
     summary: Nearly 10% of nursing home staff and about 16% of staff working in the hospitals reported experiencing COVID-19 symptoms. This study was carried out to describe settings of and regional differences in the occurrence of COVID-19 among nursing staff, analysing COVID-19 symptoms, testing and diagnosis procedures.
    keywords: covid-19; license; medrxiv; nurses; nursing; preprint; symptoms
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        item: #2339 of 7819
          id: cord-279913-lgdmlies
      author: Katz, D. H.
       title: Proteomic Profiling in Biracial Cohorts Implicates DC-SIGN as a Mediator of Genetic Risk in COVID-19
        date: 2020-06-11
       words: 4034
      flesch: 46
     summary: Further, while changes in aptamer binding are typically reflective of protein levels, it may be the case that ABO-mediated glycosylation alters aptamer binding, thus changing the measurement of the protein without a true change in protein levels. While the proteomic profiling discussed here is extensive, it does not cover the entire proteome, and important protein associations may be missed as a result.
    keywords: abo; covid-19; data; heart; jhs; locus; preprint; protein; risk; study
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        item: #2340 of 7819
          id: cord-279933-l7nen2uj
      author: Hsu, Jeffrey J.
       title: COVID‐19 in a High‐Risk Dual Heart and Kidney Transplant Recipient
        date: 2020-04-21
       words: 2517
      flesch: 45
     summary: However, his overall course aligns with the limited prior reports of COVID-19 positive heart transplant recipients with similarly benign courses. In the sole report of heart transplant recipients with COVID-19 published thus far, the two patients from Wuhan survived and were successfully discharged home.
    keywords: article; copyright; covid-19; heart; recipients; transplant
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        item: #2341 of 7819
          id: cord-279942-y5io9qzl
      author: Chakrabarty, Rajan K.
       title: Ambient PM2.5 exposure and rapid spread of COVID-19 in the United States
        date: 2020-11-09
       words: 3079
      flesch: 37
     summary: Li et al. 2020b; Wu et al. 2020a; Xu et al. 2020) J o u r n a l P r e -p r o o f Journal Pre-proof Exposure to PM 2.5 has a well-established association with increased risks and severe outcomes during infectious disease outbreaks, including COVID-19, the 2009 H1N1, and the 1918 Spanish influenza pandemics (Clay et al. 2018 (Clay et al. , 2019 Morales et al. 2017; Wu et al. 2020b )
    keywords: covid-19; disease; et al; exposure
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        item: #2342 of 7819
          id: cord-279960-1phc0wds
      author: Zhao, Ai
       title: Dietary Diversity among Chinese Residents during the COVID-19 Outbreak and Its Associated Factors
        date: 2020-06-06
       words: 5975
      flesch: 48
     summary: Those alterations in activities and behaviors during a pandemic period collectively influence and potentially impair food diversity. China has been experiencing a rapid growth of online food ordering and delivery services in recent years.
    keywords: china; chinese; covid-19; diversity; food; hdds; participants; people; person; study
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        item: #2343 of 7819
          id: cord-279991-w2aoogjj
      author: Labrague, Leodoro J.
       title: Fear of Covid‐19, psychological distress, work satisfaction and turnover intention among frontline nurses
        date: 2020-09-27
       words: 4694
      flesch: 43
     summary: To date, no studies have been conducted examining how this fear of COVID‐19 contributes to health, well‐being and work outcomes in frontline nurses. Frontline nurses who reported not having attended COVID‐19‐related training and those who held part‐time job roles reported increased fears of COVID‐19.
    keywords: covid-19; fear; frontline; health; job; nurses; scale; study
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        item: #2344 of 7819
          id: cord-280005-i9fp5rys
      author: Wang, Mengmei
       title: Treatment of COVID-19 Patients with Prolonged Post-Symptomatic Viral Shedding with Leflunomide -- a Single-Center, Randomized, Controlled Clinical Trial
        date: 2020-09-21
       words: 3192
      flesch: 42
     summary: key: cord-280005-i9fp5rys authors: Wang, Mengmei; Zhao, Yang; Hu, Weihua; Zhao, Dong; Zhang, Yunting; Wang, Tao; Zheng, Zhishui; Li, Xiaochen; Zeng, Shaolin; Liu, Zhenlian; Lu, Li; Wan, Zhihui; Hu, Ke title: Treatment of COVID-19 Patients with Prolonged Post-Symptomatic Viral Shedding with Leflunomide -- a Single-Center, Randomized, Controlled Clinical Trial date: 2020-09-21 journal: Clin Infect Dis DOI: 10.1093/cid/ciaa1417 sha: doc_id: 280005 cord_uid: i9fp5rys OBJECTIVE: To evaluate the efficacy and safety of leflunomide, an approved dihydroorotate dehydrogenase inhibitor, to treat COVID-19 patients with prolonged post-symptomatic viral shedding. In COVID-19 patients with prolonged PCR positivity, no benefit in terms of the duration of viral shedding was observed with the combined treatment of leflunomide and IFN α-2a beyond IFN α-2a alone.
    keywords: covid-19; days; group; leflunomide; patients; shedding; treatment; trial
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        item: #2345 of 7819
          id: cord-280029-g1k3zlax
      author: Gabutti, Giovanni
       title: Coronavirus: Update Related to the Current Outbreak of COVID-19
        date: 2020-04-08
       words: 5020
      flesch: 50
     summary: As of March 9, 2020, considering that new cases of COVID-19 registered in Italy had started to increase considerably and national restrictive measures had not yet been put in place, the Council of Ministers issued a decree law with measures to prohibit access to and exit from the country as well as suspension of all the activities that were not strictly necessary [46, 47] . Patients with COVID-19 should receive supportive care to help relieve symptoms, and, for severe cases, treatment should include care to support vital organ functions
    keywords: cases; china; coronavirus; cov-2; covid-19; health; infection; mers; patients; sars; transmission
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        item: #2346 of 7819
          id: cord-280043-bm0qkrod
      author: Esagian, Stepan M.
       title: Challenges in Abdominal Organ Transplantation During the COVID-19 Pandemic
        date: 2020-06-04
       words: 4222
      flesch: 30
     summary: Meanwhile, the lack of data surrounding many aspects of COVID-19 disease and its effects on transplant patients further complicate the situation and may necessitate the application of more drastic measures. Transplant recipients are most often on life-long immunosuppressants, which predispose them to infections, while transplant candidates usually have a combination of underlying comorbidities and tend to be older compared to the general population.
    keywords: covid-19; disease; liver; organ; patients; recipients; sars; transplant; transplantation
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        item: #2347 of 7819
          id: cord-280050-fktc778q
      author: Tahir, Shumaila
       title: Epidemiological and Clinical Features of SARS-CoV-2: A Retrospective Study from East Karachi, Pakistan
        date: 2020-06-17
       words: 3425
      flesch: 49
     summary: Our study primarily highlights the scenario of COVID-19 cases in the East district of Karachi, Pakistan. Almost a quarter (23.3%) of Italy's population is over 65 years where a significantly higher number of COVID-19 cases and deaths were reported with case fatality rate (CFR) of 0.7% in 40-49 years, 27.7% in >80 years, and 96.9% deaths occurring in adults aged 60 years and greater [15] .
    keywords: cases; covid-19; disease; pakistan; patients; sars; study; symptoms
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        item: #2348 of 7819
          id: cord-280055-5iwo6tlb
      author: Vieira, Tiago
       title: The lose-lose dilemmas of Barcelona’s platform delivery workers in the age of COVID-19
        date: 2020-12-31
       words: 8965
      flesch: 47
     summary: This deems police controls particularly unwelcome for many PDW, with consequences ranging from fines to severe legal complications. If you know of any account please I'm very unsettled Beyond income, a decisive element to understand the whole context lived by most PDW is the way the apps are run, commonly known as application-based management.
    keywords: account; covid-19; group; interactions; interviews; pdw; people; platform; police; precarity; research; social; whatsapp; work; workers
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        item: #2349 of 7819
          id: cord-280068-rszu1c48
      author: Twomey, Julianne D.
       title: COVID-19 update: The race to therapeutic development
        date: 2020-10-24
       words: 6208
      flesch: 26
     summary: Heparin, previously approved as a blood thinner, was originally used in COVID-19 clinical trials to limit lung injury and prevent blood clot formation (Ayerbe et al., 2020; . We highlight two major lines of therapeutic strategies for COVID-19 treatment: 1) repurposing the existing drugs for use in COVID-19 patients, such as antiviral medications (e.g., remdesivir) and immunomodulators (e.g., dexamethasone) which were previously approved for other disease conditions, and 2) novel biological products that are designed to target specific molecules that are involved in SARS-COV-2 viral entry, including neutralizing antibodies against the spike protein of SARS-COV-2, such as REGN-COV2 (an antibody cocktail) and LY-COV555, as well as recombinant human soluble ACE2 protein to counteract SARS-COV-2 binding to the transmembrane ACE2 receptor in target cells.
    keywords: ace2; antibodies; coronavirus; cov-2; covid-19; et al; human; infection; patients; potential; protein; sars; spike; treatment; virus
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        item: #2350 of 7819
          id: cord-280078-jbwphya5
      author: Bonati, Elena
       title: Postoperative vocal fold dysfunction in covid-19 era: are we still in time for a recovery?
        date: 2020-08-09
       words: 1050
      flesch: 38
     summary: It has been demonstrated in a recent prospective multicentric study that it has concordance with laryngoscopy in the majority of cases and so it can be a valid alternative as first-line exam for vocal fold examination, pre-and postoperatively. A meta-analysis about therapy for vocal fold paresis/ paralysis after thyroidectomy concluded that the timing of therapy for unilateral vocal fold paralysis after thyroidectomy has a significant impact on the effect size, being significantly greater if therapy is performed within 12 months.
    keywords: covid-19; health; patients
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        item: #2351 of 7819
          id: cord-280089-x8fs34d7
      author: Park, Hayne Cho
       title: Korean clinical practice guidelines for preventing transmission of coronavirus disease 2019 (COVID-19) in hemodialysis facilities
        date: 2020-06-30
       words: 3052
      flesch: 45
     summary: HD patients receive treatment three times a week in a limited space and are particularly vulnerable to infection due to impaired immunity and environmental susceptibility [7] . 4. Contacts are defined as HD patients and healthcare workers who have been in contact with a confirmed case.
    keywords: case; covid-19; guidelines; patient; unit
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        item: #2352 of 7819
          id: cord-280133-c0k3uag9
      author: Artese, Flavia
       title: Covid-19: The aftermath for orthodontics
        date: 2020
       words: 1125
      flesch: 58
     summary: Holden Thorp, editor-in-chief of Science Journals, couldn't have written a better editorial 5 which echoed the voices of world researchers. So much so that leaders in the world seem to be lost, divided in their roles of great responsibility, between saving lives due to the corona virus or focusing on the consequences of the economic lag that will follow due to social isolation.
    keywords: covid-19; information; orthodontics; world
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        item: #2353 of 7819
          id: cord-280147-xvzi1i0v
      author: Consoli, Letizia
       title: 2019 novel coronavirus (COVID-19) pneumonia complications: the importance of lung ultrasound
        date: 2020-06-19
       words: 1390
      flesch: 41
     summary: In addition to these primary imaging methods, lung ultrasound (LUS) provides a timely bedside evaluation of COVID-19 patients, both in the primary assessment and during monitoring to adjust treatment plan [10] . Moreover, chest radiography and computed tomography (CT) scan complete the diagnostic approach to COVID-19 patients, usually showing groundglass opacities, sometimes associated with consolidative patterns
    keywords: coronavirus; covid-19; lung; patients; ultrasound
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        item: #2354 of 7819
          id: cord-280164-dukccrjb
      author: Nachega, Jean B.
       title: Responding to the Challenge of the Dual COVID-19 and Ebola Epidemics in the Democratic Republic of Congo—Priorities for Achieving Control
        date: 2020-06-19
       words: 2310
      flesch: 45
     summary: Third, the follow-up of COVID-19 contacts is modeled after our EVD experience using contact-tracers and community health workers (CHCWs) at the peripheral level: health areas, neighborhoods, and villages. 14 Serological testing for antiviral antibodies is unavailable in the DRC and is unsuitable for diagnosing active COVID-19 cases.
    keywords: cases; covid-19; drc; evd; health; outbreak; response
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        item: #2355 of 7819
          id: cord-280182-615096py
      author: Govindan, Kannan
       title: A decision support system for demand management in healthcare supply chains considering the epidemic outbreaks: A case study of coronavirus disease 2019 (COVID-19)
        date: 2020-05-07
       words: 5438
      flesch: 47
     summary: Therefore, this paper, for the first time, develops a practical decision support system based on physicians' knowledge and fuzzy inference system (FIS) in order to help with the demand management in the healthcare supply chain, to reduce stress in the community, to break down the COVID-19 propagation chain, and, generally, to mitigate the epidemic outbreaks for healthcare supply chain disruptions. Epidemic outbreaks are specifically considered among supply chain disruptions.
    keywords: approach; chain; disaster; fis; fuzzy; group; healthcare; supply; system; user
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        item: #2356 of 7819
          id: cord-280195-646xesqp
      author: Spencer, Hunter C.
       title: COVID-19 presenting as neutropenic fever
        date: 2020-06-13
       words: 608
      flesch: 48
     summary: Follow up denotes labs acquired 2 weeks post-discharge Clinical characteristics of coronavirus disease 2019 in China Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the Infectious Diseases Society of America Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan China: a retrospective cohort study Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Clinical features of patients infected with 2019 novel coronavirus in Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations As COVID-19 spreads among neutropenic patients, further observations regarding the clinical course and response to emerging therapies are necessary to understand the host-virus interaction in this high-risk group.
    keywords: covid-19; fever; patients
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        item: #2357 of 7819
          id: cord-280206-49qjyhrd
      author: Szczerbińska, Katarzyna
       title: Could we have done better with COVID-19 in nursing homes?
        date: 2020-07-16
       words: 3212
      flesch: 46
     summary: As a result, less than 1% of nursing home residents in the Netherlands died of COVID-19 in a hospital, while 30% of them remained in the facilities to die. The PACE project conducted in 6 EU countries showed that despite most nurses and care givers were relatively knowledgeable about the general principles of care for nursing home residents, in some countries, their knowledge of end-of-life care was rather poor
    keywords: care; covid-19; facilities; ltc; nursing; residents; staff
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        item: #2358 of 7819
          id: cord-280210-6xivdgvt
      author: Eichner, E. Randy
       title: Writing on Sports Medicine in Pandemic Times
        date: 2020-07-08
       words: 1661
      flesch: 72
     summary: A laboratory study even suggests that allergic asthma may fend off severe COVID-19. Health organizations cautioned that those with asthma may be at higher risk, but they based this on questionnaires with an umbrella box (to check or not) that included asthma, chronic obstructive pulmonary disease, or emphysema.
    keywords: antibody; asthma; covid-19; history; quarantine
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        item: #2359 of 7819
          id: cord-280221-s6oxq772
      author: Montelongo-Jauregui, Daniel
       title: Convalescent serum therapy for COVID-19: A 19th century remedy for a 21st century disease
        date: 2020-08-12
       words: 2045
      flesch: 36
     summary: Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding The SARS, MERS and novel coronavirus (COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned? Origin and evolution of pathogenic coronaviruses Bat Coronaviruses in China Remdesivir for the Treatment of Covid-19-Preliminary Report The convalescent sera option for containing COVID-19 Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma Effectiveness of convalescent plasma therapy in severe COVID-19 patients Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-19 Treatment with convalescent plasma for COVID-19 patients in Wuhan Convalescent serum lines up as first-choice treatment for coronavirus Early Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients Ueber das Zustandekommen der Diphtherie-Immunitä t und der Tetanus-Immunitä t bei A pilot study exploring the feasibility of convalescent plasma transfusion to rescue a group of 10 patients with severe disease showed that 1 dose (200 mL) of convalescent plasma with high neutralizing antibody titers was well tolerated, resulted in disappearance of viremia, and improved clinical symptoms in all patients within days of administration [8] .
    keywords: antibodies; convalescent; covid-19; plasma; therapy; treatment
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        item: #2360 of 7819
          id: cord-280223-6ro2deuv
      author: Ciacchini, Benedetta
       title: Reluctance to seek pediatric care during the COVID-19 pandemic and the risks of delayed diagnosis
        date: 2020-06-29
       words: 1968
      flesch: 44
     summary: It is located in the city of Alessandria, in the north-west of Italy, very close to an infectious outbreak that currently counts a total of 3346 confirmed COVID-19 cases, (12.9% of total Piedmont's cases, the second most Italian region involved in this pandemic outbreak) While COVID-19 per se does not seem to represent a significant threat to the pediatric population, which generally presents a benign course and a low lethality, the current emergency might negatively affect the care of pediatric patients and overall children welfare.
    keywords: a&e; cases; covid-19; emergency; patients
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        item: #2361 of 7819
          id: cord-280227-4v4mbej4
      author: Dasgupta, Prokar
       title: Covid‐19 and urology
        date: 2020-05-29
       words: 492
      flesch: 41
     summary: Prokar Dasgupta, BJUI Editor-in-Chief COVID-19 pandemic -is virtual urology clinic the answer to keeping the cancer pathway moving? Global challenges to urology practice during the COVID-19 pandemic COVID-19 and urology: a comprehensive review of the literature Slowdown of urology residents' learning curve during the COVID-19 emergency Bolstering the surgical response to COVID-19: how virtual technology will save lives and safeguard surgical practice A further article on the use of virtual technology solutions by Karim et al.
    keywords: covid-19
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        item: #2362 of 7819
          id: cord-280231-jo3grxd5
      author: Hardenberg, Jan‐Hendrik
       title: Covid‐19, ACE2 and the kidney
        date: 2020-08-02
       words: 3911
      flesch: 51
     summary: 25 That Covid-19 patients develop acute kidney injury (AKI) would not be a surprise. A brief overview of Covid-19 patients, acute kidney injury (AKI) and renal-replacement therapies (RRT) Stepwise multivariate binary logistic regression analyses showed that severity of pneumonia was the risk factor most commonly associated with lower odds of proteinuric or haematuric remission and recovery from AKI.
    keywords: ace2; acute; aki; angiotensin; cov-2; covid-19; disease; enzyme; kidney; patients; sars
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        item: #2363 of 7819
          id: cord-280234-anlytu3q
      author: Memar, Elmira Haji Esmaeil
       title: Fulminant hepatic failure: a rare and devastating manifestation of Coronavirus disease 2019 in an 11-year-old boy
        date: 2020-09-29
       words: 1550
      flesch: 35
     summary: key: cord-280234-anlytu3q authors: Memar, Elmira Haji Esmaeil; Mamishi, Setareh; Ekbatani, Meisam Sharifzadeh; Alimadadi, Hosein; Yaghmaei, Bahareh; Chegini, Victoria; Janani, Somayeh; Mahmoudi, Shima title: Fulminant hepatic failure: a rare and devastating manifestation of Coronavirus disease 2019 in an 11-year-old boy date: 2020-09-29 journal: Arch Pediatr DOI: 10.1016/j.arcped.2020.09.009 sha: doc_id: 280234 cord_uid: anlytu3q Although several typical manifestation of novel coronavirus disease 2019 (COVID-19) including respiratory symptoms, weakness, fever, and fatigue have been reported, some rare and novel manifestations have also been observed, particularly in children. We report a pediatric case of fulminant hepatic failure associated with COVID-19.
    keywords: covid-19; disease; failure; liver
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        item: #2364 of 7819
          id: cord-280241-h16s6wwm
      author: McStay, R.
       title: COVID-19: looking beyond the peak. Challenges and tips for radiologists in follow-up of a novel patient cohort
        date: 2020-10-08
       words: 4860
      flesch: 27
     summary: Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) Association of cardiac injury with mortality in hospitalised patients with COVID-19 in Wuhan, China Neurological manifestations of hospitalised patients with COVID-19 in Wuhan, China: a retrospective case series study Myocardial injury and COVID-19: possible mechanisms Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Clinical characteristics of 138 hospitalised patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China The variety of cardiovascular presentations of COVID-19 Myocarditis revealing COVID-19 infection in a young patient COVID-19 and cardiovascular disease Cardiac involvement in recovered COVID-19 patients identified by magnetic resonance imaging SARS-CoV-2-induced Kawasaki-like hyperinflammatory syndrome: a novel COVID phenotype in children COVID-19 and Kawasaki disease: novel virus and novel case COVID-19 and Kawasaki disease: finding the signal in the noise Kidney disease is associated with in-hospital death of patients with COVID-19 Gastrointestinal and liver manifestations in patients with COVID-19 Liver injury during highly pathogenic human coronavirus infections Neurological manifestations and complications of COVID-19: a literature review Posterior reversible encephalopathy syndrome (PRES) as a neurological association in severe COVID-19 Transient cortical blindness in COVID-19 pneumonia; a PRES-like syndrome: case report COVID-19 infection and circulation ACE2 levels: protective role in women and children. It would seem reasonable, therefore, to suggest that although patients may develop acute PE secondary to a severe illness and hospitalisation, the pronounced inflammatory response seen in a cohort of COVID-19 patients results in a substantial pro-thrombotic tendency.
    keywords: acute; covid-19; disease; follow; imaging; lung; patients; pneumonia
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        item: #2365 of 7819
          id: cord-280280-9jr7ekbu
      author: Bertoncelli, Deborah
       title: COVID19: potential cardiovascular issues in pediatric patients
        date: 2020-05-11
       words: 3395
      flesch: 20
     summary: Children do not seem to count for a large proportion of COVID-19 disease infections. According to a morbidity/mortality report by the Centers for Disease Control of the United States, among the pediatric cases with information on underlying conditions, the most common underlying condition after chronic lung disease was cardiovascular disease (58, 59) .
    keywords: acute; children; coronavirus; cov-2; covid-19; disease; infection; patients; sars
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        item: #2366 of 7819
          id: cord-280331-iu2e14jo
      author: Taboe, Hémaho B.
       title: Predicting COVID-19 spread in the face of control measures in West-Africa
        date: 2020-07-29
       words: 6965
      flesch: 46
     summary: Combining two or more measures is better for disease control, e.g., if asymptomatic cases are contact traced or identified and isolated in less than 8 days, only about 29% reduction in the disease transmission rate is required for disease elimination. Thus, disease control is more difficult if it takes long to contact trace and isolate asymptomatic humans.
    keywords: africa; asymptomatic; cases; control; covid-19; disease; measures; pandemic; reduction; transmission; west
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        item: #2367 of 7819
          id: cord-280358-ru2hv6pz
      author: Auvinen, R.
       title: Comparison of the clinical characteristics and outcomes of hospitalized adult COVID-19 and influenza patients: a prospective observational study
        date: 2020-06-29
       words: 4223
      flesch: 46
     summary: COVID-19 patients were hospitalized longer than influenza patients (6 days COVID-19 patients were hospitalized on average on day 10 of symptoms compared with day 3 for influenza patients ( Table 2 ).
    keywords: author; covid-19; funder; influenza; medrxiv; patients; perpetuity; preprint; study
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        item: #2368 of 7819
          id: cord-280361-242yq90p
      author: Emmanuel, Stip
       title: Psychiatric adverse events with hydrochloroquine during COVID-19 Pandemic
        date: 2020-06-20
       words: 1110
      flesch: 22
     summary: Active clinical trials were Chloroquine and hydroxychloroquine for the prevention or treatment of Novel Coronavirus Disease (COVID-19) in Africa: caution for inappropriate off-label use in healthcare settings Antimalarial drugs and the prevalence of mental and neurological manifestations: A systematic review and metaanalysis Chloroquine for the 2019 novel coronavirus Neurological and psychiatric safety of tafenoquine in Plasmodium vivax relapse prevention: a review Safety and effectiveness of antimalarial therapy in sickle cell disease: a systematic review and network meta-analysis Safety considerations with chloroquine, hydroxychloroquine and azithromycin in the management of SARS-CoV-2 infection Neuropsychiatric adverse events of chloroquine: A real-world pharmacovigilance study using the FAERS database Malaria control strategies in French armed forces Use of antiviral drugs to reduce COVID-19 transmission An Outbreak of Malaria in US Army Rangers Returning From Afghanistan Covid-19: US gives emergency approval to hydroxychloroquine despite lack of evidence Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro Issues relevant to mental health promotion in frontline health care providers managing quarantined/isolated COVID19 patients Psychosis following chloroquine ingestion: a 10-year comparative study from a malaria-hyperendemic district of India Exacerbations of bipolar disorder triggered by chloroquine in systemic lupus erythematosus-a case report Chloroquine psychosis Chloroquine psychosis masquerading as PCP: a case report Transient global amnesia following ingestion of chloroquine Psychosis likely induced by hydropxychloroquine in a patient with chronic Q fever: a case report and clinically relevant review of pharmacology Antimalarial psychosis revisited Toxic psychosis due to chloroquine Psychiatric symptoms induced by hydroxychloroquine Behavorial toxicity and equivocal suicide associated with chloroquine and its derivatives Hydroxychloroquine-induced acute psychosis in a systemic lupus erythematosus female Suicide by skull stab wounds: a case of drug-induced psychosis Chloroquine-associated psychosis mimicking very late-onset schizophrenia: case report Manic episode Lovestone S. Chloroquine-induced mania Psychose aiguë après prise de chloroquine Prolonged neuropsychiatric effects following management of chloroquine intoxication with psychotropic polypharmacy Chloroquine psychosis: a chemical psychosis? Toxic psychosis during chloroquine treatment Two cases of chloroquine psychosis Psychotic symptoms in volunteers serving overseas Insomnia Lupus Reis J. Insomnia induced by chloroquine in the treatment of lupus erythematosus disseminatus Psychiatric complications with chloroquine and quinacrine Chloroquine-induced recurrent psychosis Toxic psychosis due to quinacrine and chloroquine Serious psychiatric symptoms after chloroquine treatment following experimental malaria infection Chloroquine seizures Psychosis with paranoid delusions after a therapeutic dose of mefloquine: a case report Toxic psychosis : a complication of antimalarial therapy key: cord-280361-242yq90p authors: Emmanuel, Stip; Ostlundh, Linda title: Psychiatric adverse events with hydrochloroquine during COVID-19 Pandemic date: 2020-06-20 journal: Asian J Psychiatr DOI: 10.1016/
    keywords: chloroquine; covid-19; hydrochloroquine; psychosis; treatment
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        item: #2369 of 7819
          id: cord-280370-td8b6fap
      author: Álvarez, Miguel Ángel Lara
       title: Mortalidad por Covid-19 en pacientes con cáncer en un hospital de Madrid durante las primeras 3 semanas de epidemia
        date: 2020-05-19
       words: 1686
      flesch: 48
     summary: 3,4% de los casos confirmados falleciendo por la infección 15 (41,6% de mortalidad). Se han revisado los pacientes con cáncer fallecidos por covid-19 durante el periodo de análisis describiendo las características oncológicas, de la infección por covid-19 y de los tratamientos instaurados.
    keywords: con; covid-19; cáncer; los; pacientes; patients; por
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        item: #2370 of 7819
          id: cord-280372-u56ydlve
      author: Smith, L. E.
       title: The impact of believing you have had COVID-19 on behaviour: Cross-sectional survey
        date: 2020-05-05
       words: 4354
      flesch: 59
     summary: key: cord-280372-u56ydlve authors: Smith, L. E.; Mottershaw, A. L.; Egan, M.; Waller, J.; Marteau, T. M.; Rubin, G. J. title: The impact of believing you have had COVID-19 on behaviour: Cross-sectional survey date: 2020-05-05 journal: nan DOI: 10.1101/2020.04.30.20086223 sha: doc_id: 280372 cord_uid: u56ydlve Objectives: To investigate whether people who think they have had COVID-19 are less likely to engage in social distancing measures compared with those who think they have not had COVID-19. Main outcome measures: Perceived immunity to COVID-19, self-reported adherence to social distancing measures (going out for essential shopping, nonessential shopping, and meeting up with friends/family; total out-of-home activity), worry about COVID-19 and perceived risk of COVID-19 to oneself and people in the UK.
    keywords: covid-19; license; medrxiv; participants; people; preprint
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        item: #2371 of 7819
          id: cord-280373-xhvhep84
      author: Faust, A.
       title: Challenges and proposed solutions in making clinical research on COVID-19 ethical. A status quo analysis across German research ethics committees
        date: 2020-08-14
       words: 3665
      flesch: 37
     summary: Currently, there are many international contributions that address ethical issues in COVID-19 research, such as in challenge studies [16] or in high-demand trials [17] . Our status quo analysis on ethical issues based on feedback from 22 German RECs broadens our understanding of the spectrum of ethical challenges in COVID-19 research as perceived from those involved in the concrete review and oversight of COVID-19 studies.
    keywords: challenges; consent; covid-19; preprint; recs; research; studies
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        item: #2372 of 7819
          id: cord-280394-v2pwvst7
      author: Ma, Lin-Lu
       title: Developments, Evolution, and Implications of National Diagnostic Criteria for COVID-19 in China
        date: 2020-05-15
       words: 2896
      flesch: 43
     summary: All changes have been compared and presented in a separated table for suspected cases, confirmed cases, and severe cases. Hence, in the seventh edition, the types were suspected case or confirmed case, with four clinical levels of severity: mild, moderate, severe, and critical cases.
    keywords: case; covid-19; criteria; diagnosis; edition; patients
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        item: #2373 of 7819
          id: cord-280410-j32tuj5s
      author: Rose, Adam J.
       title: COVID-Related Disruption—Finding the Silver Lining
        date: 2020-08-31
       words: 787
      flesch: 67
     summary: Those of us who deliver care to patients, or study patient care, or help organize patient care certainly have a lot to be depressed and worried about these days. Growing evidence shows that many non-COVID patients have stayed home with obvious heart attack symptoms rather than coming into the hospital, for fear of catching This has led to patients dying at home, increases in otherwise rare complications such as ventricular wall rupture, 2 and generally to unnecessarily severe complications from events that might have been easily managed under usual circumstances.
    keywords: healthcare; system
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        item: #2374 of 7819
          id: cord-280416-wd6jm2ms
      author: Mukhopadhyay, S.
       title: Dynamic dysregulation of IL-6 and genes functional in NETosis, complement and coagulation in severe COVID-19 illness
        date: 2020-10-14
       words: 4109
      flesch: 44
     summary: With time, both NLR and NETosis gene expression return to baseline in the severe case (red boxes and red bars respectively for case 1 in Figure 4A and 4B). . Additionally, time-course expression data from a case of severe COVID-19 reveal negative association of NETosis gene expression with respiratory function (oxygen saturation).
    keywords: covid-19; expression; illness; license; medrxiv; netosis; preprint
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        item: #2375 of 7819
          id: cord-280423-v3r7vo0o
      author: Desmazes‐Dufeu, Nadine
       title: Discordant courses of COVID‐19 in a cohabiting couple of lung transplant recipients
        date: 2020-07-31
       words: 1778
      flesch: 41
     summary: Further studies, however, are needed to confirm this role, to optimize the management of ISDs in COVID-19 lung transplant recipients, and to better understand the immuno-pathological mechanisms involved. She had no other symptoms and did not report any history of travels abroad nor any exposure to COVID-19 patients, save for her husband with whom she cohabited in a small apartment.
    keywords: covid-19; isds; lung; patients; recipients; transplant
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        item: #2376 of 7819
          id: cord-280427-smqc23vr
      author: Singla, Rubal
       title: Human animal interface of SARS-CoV-2 (COVID-19) transmission: a critical appraisal of scientific evidence
        date: 2020-09-14
       words: 7198
      flesch: 52
     summary: Various cases of human to animal transmission have also come up indicating the risk of the virus to domestic animals or pets (Oreshkova et al. 2020) . With the increasing reports of transmission of COVID-19 from infected humans to pets (like cats and dogs) and tigers and lions, there is an urgent need for public health officials to identify and investigate the possibility of virus transmission from pets to humans.
    keywords: animals; cats; cov-2; covid-19; et al; ferrets; humans; pets; rna; sars; transmission; virus
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        item: #2377 of 7819
          id: cord-280437-6u3kepat
      author: Kalippurayil Moozhipurath, R.
       title: Evidence of Protective Role of Ultraviolet-B (UVB) Radiation in Reducing COVID-19 Deaths
        date: 2020-05-12
       words: 6138
      flesch: 54
     summary: We use the cumulative number of COVID-19 deaths and case-fatality rate (CFR) as the main dependent variables to test our hypothesis and isolate UVI effect from potential confounding factors such as underlying time trends, country-specific time-constant and time-varying factors such as weather. https://doi.org/10.1101/2020.05.06.20093419 doi: medRxiv preprint COVID-19 deaths.
    keywords: covid-19; deaths; medrxiv; medrxiv preprint; perpetuity; preprint; uvi
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        item: #2378 of 7819
          id: cord-280440-35h2x8dg
      author: Mitchell, Rob
       title: A ‘new normal’: Harnessing the experience of COVID-19 for sustained improvements in global emergency care
        date: 2020-08-17
       words: 1189
      flesch: 43
     summary: ED crowding is unethical in a COVID-19 world World Health Assembly resolution 72.16: what are the implications for the Australasian College for Emergency Medicine and emergency care development in the Indo-Pacific clinical-management-of-severe-acute-respiratoryinfection-when-novel-coronavirus-(ncov)-infection-is-suspected The authors would like to acknowledge all those clinicians who, despite challenging circumstances, are providing emergency care throughout the COVID-19 pandemic. Emergency care (EC) is no exception.
    keywords: covid-19; emergency; health
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        item: #2379 of 7819
          id: cord-280470-dtb2nza1
      author: Bairagi, A. K.
       title: A Noncooperative Game Analysis for Controlling COVID-19 Outbreak
        date: 2020-05-26
       words: 4257
      flesch: 56
     summary: From this figure, we observe 350 that the total payoff increases with increasing number of home isolation individuals for 351 all considered cases. Fig. 19 shows the average individual payoff 357 for varying parentage of home isolation individuals for different scenarios.
    keywords: cases; covid-19; home; individuals; isolation; license; preprint
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        item: #2380 of 7819
          id: cord-280471-cqypwi5d
      author: Sun, Hua-Bao
       title: The changes of the peripheral CD4+ lymphocytes and inflammatory cytokines in Patients with COVID-19
        date: 2020-09-25
       words: 4349
      flesch: 53
     summary: In the patients with COVID-19, the total number of peripheral blood lymphocytes decreased mainly as the number of CD4+ T lymphocytes decreased. In patients with COVID-19, the number of peripheral blood lymphocytes decreased, mainly manifesting as a decrease in the number of CD4+ T lymphocytes, a decrease in the ratio of CD4+/CD8+ lymphocytes, and a decrease in the number of CD8+ lymphocytes; the degrees of these reductions was significantly correlated with the severity of disease.
    keywords: blood; cd4; covid-19; covid-19 group; group; lymphocytes; number; patients
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        item: #2381 of 7819
          id: cord-280491-tarb3mu7
      author: Wu, Yin
       title: Validation of the COVID-19 fears questionnaires for chronic medical conditions: A scleroderma patient-centered intervention network COVID-19 cohort study
        date: 2020-10-08
       words: 4285
      flesch: 45
     summary: Exploratory factor analysis (EFA) and item analysis were used to select items for inclusion. Items were considered for removal if (1) the corrected item-total correlation was lower than 0.5; 44, 45 (2) the factor loading was lower than 0.6; 44, 45 or (3) there were high conceptual overlap/redundancy with other items.
    keywords: conditions; covid-19; factor; fear; item; people; questionnaire
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        item: #2382 of 7819
          id: cord-280521-sqhzcm87
      author: Qazi, Saqib Hamid
       title: Continuing and ensuring surgical care for children during COVID and post-COVID crisis
        date: 2020-08-21
       words: 413
      flesch: 38
     summary: key: cord-280521-sqhzcm87 authors: Qazi, Saqib Hamid; Dogar, Sohail Asghar; Hamid, La-Raib; Pirzada, Areeba Nadeem; Saleem, Ayesha; Das, Jai K title: Continuing and ensuring surgical care for children during COVID and post-COVID crisis date: 2020-08-21 journal: J Pediatr Surg DOI: 10.1016/j.jpedsurg.2020.08.012 sha: doc_id: 280521 cord_uid: sqhzcm87 nan The British journal of surgery Global guidance for surgical care during the COVID-19 pandemic.
    keywords: care; covid-19
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        item: #2383 of 7819
          id: cord-280528-7ivw72l0
      author: TUFAN, Abdurrahman
       title: COVID-19, immune system response, hyperinflammation and repurposing antirheumatic drugs
        date: 2020-04-21
       words: 7073
      flesch: 37
     summary: Potential benefits of precise corticosteroids therapy for severe 2019-nCoV pneumonia Adjuvant corticosteroid therapy for critically ill patients with COVID-19 Factors associated with prolonged viral RNA shedding in patients with COVID-19 Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseases Heart conduction disorders related to antimalarials toxicity: an analysis of electrocardiograms in 85 patients treated with hydroxychloroquine for connective tissue diseases Myasthenia gravis due to hydroxychloroquine Chloroquine cardiomyopathy a review of the literature Simultaneous quantitation of hydroxychloroquine and its metabolites in mouse blood and tissues using LC-ESI-MS/ MS: an application for pharmacokinetic studies The use of antimalarial drugs against viral infection Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Influenza A virus H5N1 entry into host cells is through clathrin-dependent endocytosis pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN Fibronectin receptor modulates cyclindependent kinase activity Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology In two small observational study, use of corticosteroids did not show a survival benefit in COVID-19 patients even increased mortality rates when used in high doses [51]
    keywords: cells; coronavirus; cov-2; covid-19; cytokine; disease; hcq; il-6; immune; infection; patients; protein; sars; studies; syndrome; treatment; use
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        item: #2384 of 7819
          id: cord-280538-lrvqhx98
      author: Wang, Haiyan
       title: Using A Partial Differential Equation with Google Mobility Data to Predict COVID-19 in Arizona
        date: 2020-06-30
       words: 4670
      flesch: 54
     summary: The present paper aims to develop, for the first time in the literature, a specific PDE model between county-regions for forecasting daily COVID-19 cases and further quantifying the influences of the mobility of the community on the changing the number of COVID-19 cases in the state of Arizona. Accurate forecasting for COVID-19 cases will help governments to implement necessary measures and convince more people to take personal precautions to combat the virus.
    keywords: arizona; cases; covid-19; covid-19 cases; data; model; pde; regions
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        item: #2385 of 7819
          id: cord-280540-yw8o3c1l
      author: Patel, A. P.
       title: Race, Socioeconomic Deprivation, and Hospitalization for COVID-19 in English participants of a National Biobank
        date: 2020-05-02
       words: 1212
      flesch: 43
     summary: We investigate the racial and socioeconomic associations of COVID-19 hospitalization among 418,794 participants of the UK Biobank, of whom 549 (0.13%) had been hospitalized. To understand the relationship between socioeconomic status and COVID-19 hospitalization, individuals were stratified at enrollment into deciles of the Townsend Deprivation Index, a previously validated composite metric based on employment status, car or home ownership, and household crowding.
    keywords: medrxiv; participants; preprint
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        item: #2386 of 7819
          id: cord-280551-9hoxy5ok
      author: Kim, Donghee
       title: Predictors of Outcomes of COVID-19 in Patients with Chronic Liver Disease: US Multi-center Study
        date: 2020-09-17
       words: 3589
      flesch: 44
     summary: Patients presenting with GI symptoms of diarrhea (OR 1.89, 95% CI: 1.30-2.74) or nausea/vomiting (OR 1.84, 95% CI: 1.27-2.68) were more likely to have severe COVID-19 than patients without GI symptoms (Table 2) . J o u r n a l P r e -p r o o f Trends in the Burden of Chronic Liver Disease Among Hospitalized US Adults The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study Burden of liver diseases in the world Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study SARS-associated viral hepatitis caused by a novel coronavirus: report of three cases Histopathology of Middle East respiratory syndrome coronovirus (MERS-CoV) infection -clinicopathological and ultrastructural study Liver injury in COVID-19: management and challenges Clinical Features of COVID-19-Related Liver Damage Clinical Characteristics and Outcomes of COVID-19 Among Patients with Pre-Existing Liver Disease in United States: A Multi-Center Research Network Study High rates of 30-day mortality in patients with cirrhosis and COVID-19 High Mortality Rates for SARS-CoV-2 Infection in Patients with Pre-existing Chronic Liver Disease and Cirrhosis:
    keywords: cld; covid-19; disease; liver; mortality; patients
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        item: #2387 of 7819
          id: cord-280554-9jp85yzz
      author: Lamure, Sylvain
       title: Determinants of outcome in Covid-19 hospitalized patients with lymphoma: A retrospective multicentric cohort study
        date: 2020-10-13
       words: 4553
      flesch: 43
     summary: This encourages the application of standard Covid-19 treatment, including intubation, for lymphoma patients with Covid-19 lymphoma diagnosis, under firstor second-line chemotherapy, or in remission. Other limitations were the retrospective nature of the study and the study design, which did not allow a direct comparison between lymphoma patients with Covid-19 and Covid-19 patients without lymphoma.
    keywords: covid-19; fees; lymphoma; patients; refractory; study; treatment; years
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        item: #2388 of 7819
          id: cord-280561-2t72q2ba
      author: Rani, Uma
       title: Platform Work and the COVID-19 Pandemic
        date: 2020-10-06
       words: 2974
      flesch: 48
     summary: At the same time, with the lack of health insurance coverage for platform workers in many countries, even getting tested for COVID-19 may be challenging. There is a very clear indication that with the ICT revolution and the proliferation of the internet, platform work will continue to grow.
    keywords: covid-19; demand; labour; online; pandemic; platforms; work; workers
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        item: #2389 of 7819
          id: cord-280579-osodvntp
      author: Ali, Hussain
       title: Impact of novel coronavirus (COVID-19) on daily routines and air environment: evidence from Turkey
        date: 2020-09-22
       words: 3430
      flesch: 53
     summary: COVID-19 epidemic not only brought the health risk but also create intolerable psychological pressure on Chinese people and all over the world (Xiao 2020; Duan 2020) . Due to the continuous spread of COVID-19 epidemic causes delays in starting school, college, and universities in the overall country, and it is expected to affect the mental health of students (Li et al. 2020 ).
    keywords: air; covid-19; data; environment; pandemic; people; routines; study; turkey; turkish
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        item: #2390 of 7819
          id: cord-280628-ok62havd
      author: Groß, Sonja
       title: SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications
        date: 2020-04-30
       words: 4463
      flesch: 34
     summary: This, and the fact that SARS-CoV-2 hijacks ACE2 for cell-entry, have spurred controversial discussions on the role of ACE2 in COVID-19 patients. We further highlight currently investigated and upcoming therapy options for COVID-19 patients with cardiac disease conditions. launched to determine the presence of anti-SARS-CoV-2 antibodies.
    keywords: ace2; angiotensin; cardiac; coronavirus; covid-19; disease; infection; patients; receptor; sars; system
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        item: #2391 of 7819
          id: cord-280630-2g7ygxys
      author: Koo, Bo Kyung
       title: Glove-Wall System for Respiratory Specimen Collection and COVID-19 Mass Screening
        date: 2020-04-14
       words: 532
      flesch: 46
     summary: key: cord-280630-2g7ygxys authors: Koo, Bo Kyung; Bang, Ji Hwan; Kim, Sun-Young; Kim, Eun Jin; Park, Sang-Won title: Glove-Wall System for Respiratory Specimen Collection and COVID-19 Mass Screening date: 2020-04-14 journal: Infect Chemother DOI: 10.3947/ic.2020.52.2.219 sha: doc_id: 280630 cord_uid: 2g7ygxys nan In response to the coronavirus disease 2019 (COVID-19) pandemic, Korea has devised an effective strategy for massive diagnostic testing combined with isolation [1] [2] [3] . Clinical characteristics of coronavirus disease 2019 in China Korean Society of Infectious Diseases; Korean Society of Pediatric Infectious Diseases Report on the epidemiological features of coronavirus disease 2019 (COVID-19) outbreak in the Republic of Korea from Laboratory biosafety guidance related to the novel coronavirus (2019-nCoV) Guidelines for environmental infection control in health-care facilities Guidelines for preventing the transmission of Mycobacterium tuberculosis in health-care settings We greatly appreciate all members of COVID-19 Boramae Task Force Team.
    keywords: coronavirus; covid-19; gloves
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        item: #2392 of 7819
          id: cord-280631-9hq9e1o6
      author: Xu, Zheng‐Li
       title: COVID‐19 & Allogeneic Transplant: Activity and Preventive Measures for Best Outcomes in China
        date: 2020-06-01
       words: 2057
      flesch: 38
     summary: Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Acute leukemia in the time of COVID-19 The impact of COVID-19 on the provision of donor hematopoietic stem cell products worldwide: collateral damage Available from A review of hematopoietic cell transplantation in China: data and trends during 2008-2016 Haploidentical versus Matched-Sibling Transplant in Adults with Philadelphia-Negative High-Risk Acute Lymphoblastic Leukemia: A Biologically Phase III Randomized Study Haploidentical vs identical-sibling transplant for AML in remission: a multicenter, prospective study Haploidentical transplant for myelodysplastic syndrome: registry-based comparison with identical sibling transplant The consensus on indications, conditioning regimen, and donor selection of allogeneic hematopoietic cell transplantation for hematological diseases in China-recommendations from the Chinese Society of Hematology Accepted Article Outside the epicentre (Wuhan), transplantation activity in China was not halted.
    keywords: cell; covid-19; donors; patients; risk; transplantation
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        item: #2393 of 7819
          id: cord-280642-cvxni7cd
      author: The OpenSAFELY Collaborative,
       title: OpenSAFELY: factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients.
        date: 2020-05-07
       words: 7292
      flesch: 46
     summary: Deprivation is also a major risk factor with, again, little of the excess risk explained by co-morbidity or other risk factors. Deprivation is also a major risk factor with, again, little of the excess risk explained by co-morbidity or other risk factors.
    keywords: age; covid-19; data; death; disease; factors; hospital; license; patients; preprint; risk; study
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        item: #2394 of 7819
          id: cord-280667-wpju6pwi
      author: Feng, Yi
       title: When altruists cannot help: the influence of altruism on the mental health of university students during the COVID-19 pandemic
        date: 2020-07-10
       words: 4548
      flesch: 43
     summary: Our study focused on health psychology to understand how people responded to the threat of COVID-19, especially in terms of anxiety and depressive symptoms, which are widely considered to be indicators of negative mental health. The positive predictive effect of altruism on physical and psychological well-being has been extensively demonstrated in previous studies, but few studies have examined the effect of altruism on negative mental health outcomes when altruists cannot perform altruistic behaviours.
    keywords: affect; altruism; anxiety; covid-19; health; risk; symptoms
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        item: #2395 of 7819
          id: cord-280695-r3oldfaj
      author: Stewart, Cameron
       title: COVID-19 and Australian Prisons: Human Rights, Risks, and Responses
        date: 2020-11-09
       words: 2820
      flesch: 43
     summary: COVID-19 presents a significant threat to prisoner health. Australian prisoners also have a high prevalence of chronic conditions, with 30 per cent of prison entrants stating that they had a history of arthritis, asthma, cancer, cardiovascular disease, or diabetes (AIHW 2019).
    keywords: cent; covid-19; health; prisoners; rights; risk; rowson
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        item: #2396 of 7819
          id: cord-280722-glcifqyp
      author: Rios, V.
       title: Is there a link between temperatures and COVID-19 contagions? Evidence from Italy
        date: 2020-05-19
       words: 17652
      flesch: 45
     summary: The marginal likelihood of a model k is calculated as: where p y, X|η k , σ 2 , M k is the likelihood of model k and p η k , σ 2 |g is the prior distribution of the parameters in model M k conditional to g, the Zellgner's g-prior. In addition, the BMA framework can be extended to generate probabilistic on the relevance of the various regressors, using the Posterior Inclusion Probability (PIP) for a variable h: and the Conditional Posterior Positivity of h: where values of conditional positivity close to 1 indicate that the parameter is positive in the vast majority of considered models and values close to 0 indicate the effect on the dependent variable is negative.
    keywords: analysis; author; cases; contagions; covid-19; data; display; et al; factors; funder; importance; license; medrxiv; model; perpetuity; preprint; regional; results; temperatures; variables
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        item: #2397 of 7819
          id: cord-280747-k0x6rjdi
      author: Hashim, Muhammad Jawad
       title: Population Risk Factors for COVID-19 Mortality in 93 Countries
        date: 2020-09-17
       words: 2620
      flesch: 42
     summary: We chose to analyze Case Mortality Rates (CMR) by country population, rather than by the number of test-positive cases (CFR), since the latter is dependent on the number of tests performed in each country and this varies enormously from country to country We aimed to study the variations in CMR against population risk factors such as aging, underlying chronic diseases and social determinants such as poverty and overcrowding.
    keywords: countries; covid-19; data; factors; population; rates; risk
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        item: #2398 of 7819
          id: cord-280780-owudyf7j
      author: Kemp, Oliver J
       title: Comparison of chest X-ray interpretation by Emergency Department clinicians and radiologists in suspected COVID-19 infection: a retrospective cohort study
        date: 2020-08-28
       words: 1496
      flesch: 44
     summary: The improvement in accuracy with ED clinician experience suggests training of junior ED clinicians in the interpretation of COVID-19 related CXRs might be beneficial. We compared ED clinicians’ and radiologists’ interpretation of the CXRs according to British Society of Thoracic Imaging (BSTI) guidelines, using the area under the receiver operator curve (ROC area).
    keywords: clinicians; covid-19; interpretation; study
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        item: #2399 of 7819
          id: cord-280819-z6ucnwk0
      author: Achilonu, Ikechukwu
       title: Targeting the SARS-CoV-2 main protease using FDA-approved Isavuconazonium, a P2-P3 α-ketoamide derivative and Pentagastrin: an in-silico drug discovery approach
        date: 2020-09-02
       words: 5421
      flesch: 45
     summary: Annual review of biochemistry DrugBank: a knowledgebase for drugs, drug actions and drug targets DrugBank: a comprehensive resource for in silico drug discovery and exploration PubChem substance and compound databases PubChem as a public resource for drug discovery. Proteases are attractive targets in a rational approach to COVID-19 drug discovery.
    keywords: covid-19; discovery; drug; dynamics; energy; ligand; protease; sars; structure; studies; study
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        item: #2400 of 7819
          id: cord-280821-kc0ut4oy
      author: Venturini, Elisabetta
       title: Treatment of children with COVID-19: position paper of the Italian Society of Pediatric Infectious Disease
        date: 2020-09-24
       words: 5485
      flesch: 38
     summary: At present, few clinical trials for COVID-19 treatment involving children are ongoing [8] . Currently, American guidelines on COVID-19 treatment published in May 2020, recommend both in children and adults to use lopinavir/ritonavir only in the context of clinical trials, given the lack of effectiveness reported now in literature [9, 12] .
    keywords: children; cov-2; covid-19; days; hydroxychloroquine; infection; patients; sars; therapy; treatment; use
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        item: #2401 of 7819
          id: cord-280848-z0sbztkw
      author: Setzen, Michael
       title: COVID-19 and rhinology: A look at the future
        date: 2020-04-15
       words: 2883
      flesch: 43
     summary: COVID-19 patients harbor the virus in the nasopharynx; as a result, the Stanford Rhinology Division has recommended avoiding aerosolized sprays and instead using pledgets to mitigate this risk in the outpatient setting. Several changes have been implemented by CMS for Medicare patients that make it easier to perform telehealth visits in Otolaryngology.
    keywords: covid-19; endoscopy; office; patients; procedures; telemedicine; visits
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        item: #2402 of 7819
          id: cord-280899-zoc1hk5g
      author: Volff, Maxime
       title: No added value of the modified NEWS score to predict clinical deterioration in COVID-19 patients
        date: 2020-07-10
       words: 338
      flesch: 44
     summary: One hundred seventy-two patients Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region The variability of critical care bed numbers in Europe Novel coronavirus infection during the 2019-2020 epidemic: preparing intensive care units-the experience in Sichuan Province Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach And we gratefully acknowledge all the health care workers on the front line and all the patients involved in the study. The National Early Warning Score (NEWS) is recommended by the National Institute for Health and Care Excellence in its guidelines for predicting the risk of clinical deterioration of COVID-19 patients [3] .
    keywords: care; patients
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        item: #2403 of 7819
          id: cord-280914-6k8gpp4y
      author: Alpaslan Kocamemi, B.
       title: First Data-Set on SARS-CoV-2 Detection for Istanbul Wastewaters in Turkey
        date: 2020-05-06
       words: 2158
      flesch: 57
     summary: SARS-CoV-2 copy numbers per liter and calculated indexes in wastewater samples were summarized in Table 1 and shown in Figure 1 together with case number observed at the sampling district against influent flowrate of WWTPs. SARS-CoV-2 virus genome was detected in wastewater samples.
    keywords: cases; cov-2; covid-19; samples; sars; wastewater
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        item: #2404 of 7819
          id: cord-280917-j2a77fw3
      author: Kim, Hyun-Sook
       title: Self-care recommendations for patients with rheumatic diseases during the COVID-19 pandemic
        date: 2020-06-02
       words: 978
      flesch: 47
     summary: Smoking not only exacerbates rheumatic diseases but is also a risk factor for respiratory disease, so no smoking is especially important in the COVID-19 crisis [8] [9] [10] . key: cord-280917-j2a77fw3 authors: Kim, Hyun-Sook; Lee, Myeung-Su; Kim, HyungJin; Sung, Yoon-Kyoung; Lee, Jisoo; Shim, Seung-Cheol; Park, Sung-Hwan; Baek, Han Joo title: Self-care recommendations for patients with rheumatic diseases during the COVID-19 pandemic date: 2020-06-02 journal: Rheumatol Int DOI: 10.1007/s00296-020-04614-4 sha: doc_id: 280917 cord_uid: j2a77fw3 nan Since the first novel coronavirus disease 2019 (COVID-19) patient was diagnosed in the Republic of Korea on January 20, 2020, 10,780 patients have been diagnosed as of May 2, 2020.
    keywords: covid-19; diseases; patients; smoking
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        item: #2405 of 7819
          id: cord-280922-w6a5ec06
      author: Sen, Sanjana
       title: Predicting COVID-19 Severity with a Specific Nucleocapsid Antibody plus Disease Risk Factor Score
        date: 2020-10-29
       words: 4144
      flesch: 46
     summary: Here, ELISA and coronavirus antigen microarray (COVAM) analysis mapped antibody epitopes in the plasma of COVID-19 patients (n = 86) experiencing a wide-range of disease states. Here, ELISA and coronavirus antigen microarray (COVAM) analysis mapped antibody epitopes in the plasma of COVID-19 patients (n = 86) experiencing a wide-range of disease states.
    keywords: abs; cov-2; covid-19; disease; epitopes; patients; sars; severity; αep9
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        item: #2406 of 7819
          id: cord-280932-xhz5d4ty
      author: Acanfora, Domenico
       title: Sacubitril/valsartan in COVID-19 patients: the need for trials
        date: 2020-05-05
       words: 824
      flesch: 25
     summary: key: cord-280932-xhz5d4ty authors: Acanfora, Domenico; Ciccone, Marco Matteo; Scicchitano, Pietro; Acanfora, Chiara; Casucci, Gerardo title: Sacubitril/valsartan in COVID-19 patients: the need for trials date: 2020-05-05 journal: Eur Heart J Cardiovasc Pharmacother DOI: 10.1093/ehjcvp/pvaa044 sha: doc_id: 280932 cord_uid: xhz5d4ty nan We thank Luigi Petramala and Claudio Letizia for their comment 1 on our letter about the possible role of sacubitril/valsartan in patients with coronavirus disease 2019 (COVID-19). A Statement of Activity from the Directors of the Board and the Scientific Directors of the Italian Society of Hypertension Association of inpatient use of angiotensin converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19 Coronavirus disease 2019 (COVID-19): do angiotensin-converting enzyme inhibitors/angiotensin receptor blockers have a biphasic effect Combined neprilysin and reninangiotensin system inhibition in heart failure with reduced ejection fraction: a meta-analysis Clinical outcomes in patients with acute decompensated heart failure randomly assigned to sacubitril/valsartan or enalapril in the PIONEER-HF Trial Angiotensin-neprilysin inhibition in acute decompensated heart failure Association of cardiac injury with mortality in hospital patients with COVID-19 in Wuhan, China Prognostic value of NT-proBNP in patients with severe COVID-19
    keywords: covid-19; patients; valsartan
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        item: #2407 of 7819
          id: cord-280935-ur9x4fsa
      author: Bajwa, Hamza
       title: The Dilemma of Renal Involvement in COVID-19: A Systematic Review
        date: 2020-06-15
       words: 2171
      flesch: 45
     summary: Our review focuses on the prevalence of acute kidney insufficiency in COVID-19 patients and mortality rates in this subset of patients. It is crucial to uncover the underlying pathogenesis of acute kidney insufficiency in COVID-19 patients to understand better the reasoning behind the grave outcomes in these patients.
    keywords: aki; covid-19; disease; kidney; mortality; patients
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        item: #2408 of 7819
          id: cord-280960-88hzovg2
      author: Galani, I. E.
       title: Untuned antiviral immunity in COVID-19 revealed by temporal type I/III interferon patterns and flu comparison
        date: 2020-08-24
       words: 4633
      flesch: 45
     summary: Strikingly, COVID-19 patients became critically ill over a much 119 broader time window (up to nine days after admission) than flu patients which manifested critical 120 disease within the first day post admission. Some of the 131 critically ill patients also make IFN-α ( Fig. 2d and S5 ), albeit at significantly lower levels to mild non-132 hospitalized flu patients (Fig. 2d ) or the total of hospitalized flu patients (both critically and non-133 critically ill; p<0.05).
    keywords: covid-19; disease; fig; flu; ifn; patients; preprint; time; type
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        item: #2409 of 7819
          id: cord-280970-gy0kfhy6
      author: Peng, Fujun
       title: Management and Treatment of COVID-19: The Chinese Experience
        date: 2020-04-17
       words: 2634
      flesch: 32
     summary: Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected2020 Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Clinical features and progression of acute respiratory distress syndrome in coronavirus disease 2019. The Lancet On the use of corticosteroids for 2019-nCoV pneumonia Retrospective study of side effects of low-dose glucocorticoids in rheumatoid arthritis Early, low-dose and short-term application of corticosteroid treatment in patients with severe COVID-19 pneumonia: single-center experience from Wuhan, China.
    keywords: china; coronavirus; covid-19; novel; patients; pneumonia; sars; treatment; wuhan
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        item: #2410 of 7819
          id: cord-280975-9hgtvm6d
      author: Sarkar, Kankan
       title: Modeling and forecasting the COVID-19 pandemic in India
        date: 2020-06-28
       words: 3775
      flesch: 41
     summary: (2020) Modeling the dynamics of novel coronavirus (2019-nCov) with fractional derivative Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China Early dynamics of transmission and control of COVID-19: a mathematical modelling study The impact of the media awareness and optimal strategy on the prevalence of tuberculosis Fatmawati, Parameter estimation and fractional derivatives of dengue transmission model A dynamical model of asymptomatic carrier zika virus with optimal control strategies Dynamics of tuberculosis transmission with exogenous reinfec-440 tions and endogenous reactivations Modeling and analysis of Tuberculosis (TB) in Khyber Pakhtunkhwa Estimation of the transmission risk of the 2019-ncov and its implication for public health interventions Modelling strategies for controlling sars outbreaks Mathematical modeling of COVID-19 transmission dynamics with a case study of Wuhan Analysis and forecast of COVID-19 spreading in China, Italy and France On the definition and the computation of the basic reproduction ratio R 0 in models for infectious diseases in heterogeneous populations Reproduction numbers and subthreshold endemic equilibria for compartmental models of disease transmission A methodology for performing global uncertainty and sensitivity analysis in systems biology Avoidable errors in the modelling of out-460 breaks of emerging pathogens, with special reference to Ebola 2019-novel Coronavirus (2019-nCoV): estimating the case fatality ratea word of caution Campus quarantine (Fengxiao) for curbing emer-465 gent infectious diseases: Lessons from mitigating A/H1N1 in Xi'an To describe how best to minimize individuals impermanence and morbidity due to SARS-CoV-2, it is important to see the relative significance of various ingredients responsible for disease transmission.
    keywords: coronavirus; covid-19; individuals; model; transmission
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        item: #2411 of 7819
          id: cord-280978-rtl5ut70
      author: Lal, Rattan
       title: Home gardening and urban agriculture for advancing food and nutritional security in response to the COVID-19 pandemic
        date: 2020-06-23
       words: 2738
      flesch: 38
     summary: The specific objective of this article is to describe: 1) properties of urban soils and their suitability for growing food, 2) home gardens and urban agriculture for food and nutritional security, 3) ecosystem services provisioned by HGUA, 4) soil management options to reduce risks of contamination of urban soils by heavy metals and other pollutants, and 5) the nexus thinking of waste and water management based on the concept of recycling nutrients and water for producing food, and advancing the Sustainable Development Goals (SDGs) of the United Nations (U.N. 2015) through HGUA. Urban soils are called Anthropic soils, Anthrosols, or Technosols (FAO/UNESCO 1990) because anthropogenic control of pedogenic processes leads to drastic alterations in soil properties.
    keywords: agriculture; food; gardens; hgua; home; soil; urban
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        item: #2412 of 7819
          id: cord-280981-p0l5bpqi
      author: Keenan, Jesse M.
       title: COVID, resilience, and the built environment
        date: 2020-05-14
       words: 3926
      flesch: 22
     summary: Enterprise Community Partners A critical review of selected tools for assessing community resilience Climate change and infectious diseases in Europe Safe from the storm: creating climate-resilient health care facilities How community gardens may contribute to community resilience following an earthquake The availability heuristic, intuitive cost-benefit analysis, and climate change Health care system disaster-resilience optimization given its reliance on interdependent critical lifelines Urgent biophilia: human-nature interactions and biological attractions in disaster resilience Building health care sector resilience. On the other end of the spectrum of categorical resilience is 'community' resilience, which speaks to the capacity of communities-a collection of individuals and among social organizations-to respond, recover and accommodate external shocks and stresses (Matarrita-Cascante et al. 2017) .
    keywords: change; climate; community; covid; disaster; environment; facilities; health; healthcare; planning; resilience
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        item: #2413 of 7819
          id: cord-280996-anq680a1
      author: Agarwal, Arnav
       title: High-flow nasal cannula for acute hypoxemic respiratory failure in patients with COVID-19: systematic reviews of effectiveness and its risks of aerosolization, dispersion, and infection transmission
        date: 2020-06-15
       words: 7124
      flesch: 34
     summary: The effects of high-flow nasal cannula on intubation and re-intubation in critically ill patients: a systematic review, meta-analysis and trial sequential analysis The impact of high-flow nasal cannula on the outcome of immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis High flow nasal therapy in immunocompromised patients with acute respiratory failure: a systematic review and meta-analysis Use high-flow nasal cannula for acute respiratory failure patients in the emergency department: a meta-analysis study Effect of high-flow nasal cannula oxygen therapy in immunocompromised subjects with acute respiratory failure High-flow nasal oxygen vs standard oxygen therapy in immunocompromised patients with acute respiratory failure: a meta-analysis of randomized controlled trials Efficacy of high-flow nasal cannula therapy in intensive care units: a meta-analysis of physiological and clinical outcomes High-flow nasal cannula versus conventional oxygen therapy in patients with dyspnea and hypoxemia before hospitalization a systematic review and metaanalysis The impact of high flow nasal oxygen in the immunocompromised critically ill: a systematic review and metaanalysis The impact of high-flow nasal oxygen in the immunocompromised critically ill: a systematic review and metaanalysis High flow nasal cannula oxygen vs. conventional oxygen therapy and non-invasive ventilation in emergency department patients: a systematic review and meta-analysis High-flow nasal cannula in adults with acute respiratory failure and after extubation: a systematic review and meta-analysis Non-invasive oxygenation strategies in immunocompromised patients with acute hypoxemic respiratory failure: a pairwise and network meta-analysis of randomized controlled trials Initial non-invasive oxygenation strategies in subjects with de novo acute hypoxemic respiratory failure Use of high-flow nasal cannula for immunocompromise and acute respiratory failure: a systematic review and meta-analysis High-flow nasal cannula: a promising oxygen therapy for patients with severe bronchial asthma complicated with respiratory failure Value and safety of high flow oxygenation in the treatment of inpatient asthma: a randomized, double-blind, pilot study High-flow nasal cannula versus conventional oxygen therapy in relieving dyspnea in emergency palliative patients with do-not-intubate status: a randomized crossover study High-flow nasal cannula versus conventional oxygen therapy in emergency department patients with cardiogenic pulmonary edema: a randomized controlled trial
    keywords: acute; aerosol; cannula; certainty; covid-19; dispersion; failure; flow; hfnc; nasal; oxygen; patients; review; studies; therapy; ventilation
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        item: #2414 of 7819
          id: cord-281003-7pdhxdzc
      author: Farmakis, Dimitrios
       title: COVID‐19 and thalassaemia: A position statement of the Thalassaemia International Federation
        date: 2020-07-13
       words: 2839
      flesch: 37
     summary: The haemoglobinopathy units and clinics are thus advised to designate a dedicated room within the medical facility that will be used to provide medical care to thalassaemia patients who are suspected or confirmed COVID-19 patients. On the other hand, therapeutic advances of the past decades have resulted in a significant improvement in the once ominous prognosis of thalassaemia patients, and thus, patients with access to modern treatment modalities and well-organized follow-up programmes grow old and face a new spectrum of comorbidities related to ageing.
    keywords: blood; care; coronavirus; covid-19; disease; pandemic; patients; thalassaemia
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        item: #2415 of 7819
          id: cord-281035-tv9t0zlr
      author: Khose, Swapnil
       title: Epidemiology of the 2020 Pandemic of COVID-19 in the State of Texas: The First Month of Community Spread
        date: 2020-06-04
       words: 1666
      flesch: 56
     summary: We observed that counties with the highest CFR (> 10%) had a higher proportion of non-Hispanic Black residents (median: 3.4%; IQR: 1.7-16.9, p value < 0.01), a higher proportion of adults aged 65 and older (16.6%; IQR: 13.4-19.1, p value < 0.01), lower number of ICU beds per 100,000 population (0; IQR: 0-18.8, p value < 0.01), lower number of PCP per 1,000 population (1.2; IQR: 0.5-1.6, p value < 0.01), and a higher proportion of adults smoking in population (22.5%; IQR: In Fig. 3 To date, this is the first study to describe the epidemiology of COVID-19 in the state of Texas, with geographic trends and explaining possible county-level differences that are correlated with higher incidence and case fatality rates. Although the urban areas of Texas account for the majority of COVID-19 cases, the higher case-fatality rates and low health care capacity in rural areas need attention.
    keywords: cases; counties; covid-19; texas
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        item: #2416 of 7819
          id: cord-281038-h5iew8oo
      author: Rodríguez-Pardo, Jorge
       title: Atención al ictus agudo durante la pandemia por COVID-19. Recomendaciones Plan Ictus Madrid
        date: 2020-04-24
       words: 2769
      flesch: 32
     summary: Resultados: Las recomendaciones se estructuran en cinco líneas fundamentales: (1) Coordinar la actuación para garantizar el acceso a la asistencia hospitalaria de los pacientes con ictus, (2) Reconocer a los pacientes con ictus potencialmente infectados por COVID-19, (3) Organización adecuada para garantizar la protección de los profesionales sanitarios frente al riesgo de contagio por COVID-19, (4) la realización de Neuroimagen y otros procedimientos que conlleven contactos de riesgo de infección COVID-19 hay que procurar reducirlos y asegurar la protección, y (5) alta y seguimiento seguros procurando optimizar la ocupación hospitalaria. Las recomendaciones se estructuran en cinco líneas fundamentales: (1) Coordinar la actuación para garantizar el acceso a la asistencia hospitalaria de los pacientes con ictus, (2) Reconocer a los pacientes con ictus potencialmente infectados por COVID-19, (3) Organización adecuada para garantizar la protección de los profesionales sanitarios frente al riesgo de contagio por COVID-19, (4) la realización de Neuroimagen y otros procedimientos que conlleven contactos de riesgo de infección COVID-19 hay que procurar reducirlos y asegurar la protección, y (5) alta y seguimiento seguros procurando optimizar la ocupación hospitalaria.
    keywords: atención; con; covid-19; del; ictus; las; los; neurología; pacientes; para; por; que; recomendaciones; stroke; una
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        item: #2417 of 7819
          id: cord-281039-a7q5nzwn
      author: Rodilla, Enrique
       title: Association of Hypertension with All-Cause Mortality among Hospitalized Patients with COVID-19
        date: 2020-09-28
       words: 4808
      flesch: 41
     summary: Second, previous treatment with ACEIs/ARBs in hypertensive patients was not associated with a higher risk of all-cause mortality in hypertensive hospitalized COVID-19 patients compared to other antihypertensive drugs. Furthermore, the causal role of age in explaining coronary heart disease and stroke increases in parallel with age [17] . Treatment of HT with renin-angiotensin-aldosterone system (RAAS) inhibitors might have a beneficial effect on COVID-19 patients.
    keywords: aceis; age; angiotensin; arbs; cause; covid-19; group; mortality; patients; treatment
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        item: #2418 of 7819
          id: cord-281040-jvcgtynq
      author: Taquet, M.
       title: Bidirectional associations between COVID-19 and psychiatric disorder: a study of 62,354 COVID-19 cases
        date: 2020-08-16
       words: 5512
      flesch: 49
     summary: Anxiety and depression in patients with confirmed and suspected COVID-19 in Ecuador Anxiety and depression in COVID-19 survivors: role of inflammatory and clinical predictors Post discharge symptoms and rehabilitation needs in survivors of COVID 19 infection: a cross sectional evaluation Prevalence of depression and its association with quality of life in clinically stable patients with COVID-19 Prospective cohort study based on a community sample Prior diagnoses and medications as risk factors for COVID-19 in a Los Angeles Health System Rates of delirium associated with calcium channel blockers compared to diuretics, renin-angiotensin system agents and beta-blockers: An electronic health records network study Risk factors for SARS-CoV-2 among patients in the Oxford Royal College of General Practitioners Research and Surveillance Centre primary care network: a cross-sectional study Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study OpenSAFELY: factors associated with COVID-19 death in 17 million patients An introduction to propensity score methods for reducing the effects of confounding in observational studies The propensity score Proportional hazards tests and diagnostics based on weighted residuals Targetable biological mechanisms implicated in emergent psychiatric conditions associated with SARS-CoV-2 infection Extrapulmonary manifestations of COVID-19 Psychotic symptoms in COVID-19 patients. There are a range of physical health risk factors for COVID-19, but it is not known if there are also psychiatric risk factors.
    keywords: covid-19; diagnosis; health; license; medrxiv; patients; preprint; risk
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        item: #2419 of 7819
          id: cord-281060-1ud5hzlh
      author: Méndez Maestro, Irune
       title: Skin manifestations in patients hospitalized with confirmed COVID‐19 disease: a cross‐sectional study in a tertiary hospital
        date: 2020-09-24
       words: 1589
      flesch: 42
     summary: 2, 3 It was not until March 26 that Recalcati's article 4 analyzed skin manifestations in COVID-19 patients for the first time. The objective of this study was to examine the skin of hospitalized patients with a confirmed diagnosis of COVID‐19 disease and describe the real prevalence of skin manifestations.
    keywords: covid-19; disease; manifestations; patients
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        item: #2420 of 7819
          id: cord-281064-b69p44uq
      author: Ozder, Aclan
       title: A Novel Indicator Predicts 2019 Novel Coronavirus Infection in Subjects with Diabetes
        date: 2020-07-03
       words: 3500
      flesch: 46
     summary: This study aimed to evaluate the diagnostic role of MPV in Covid patients with diabetes. We have retrospectively analyzed the MPV values of age-and sex-matched 160 laboratory confirmed Covid patients without diabetes admitted to the Covid out-patient clinic.
    keywords: covid; diabetes; infection; mean; mpv; patients; platelet
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        item: #2421 of 7819
          id: cord-281068-bigb9890
      author: Alumran, Arwa
       title: Role of Precautionary Measures in Containing the Natural Course of Novel Coronavirus Disease
        date: 2020-07-16
       words: 2532
      flesch: 47
     summary: The number of COVID-19 cases in Saudi Arabia was expected to reach 258,283 cases by May 1, 2020 (ie, within 2 months of the onset of outbreak in Saudi Arabia) if precautionary measures had not been implemented in the country. The preventive measures massively impacted the reduction of COVID-19 cases in Saudi Arabia from the expected number of 437,097 accumulated cases by May 4, 2020, to the observed number of 28,656 accumulated cases.
    keywords: cases; covid-19; measures; number; saudi
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        item: #2422 of 7819
          id: cord-281086-fmftr5jn
      author: Morand, A.
       title: Child with liver transplant recovers from COVID-19 infection. A case report
        date: 2020-05-06
       words: 1183
      flesch: 47
     summary: key: cord-281086-fmftr5jn authors: Morand, A.; Roquelaure, B.; Colson, P.; Amrane, S.; Bosdure, E.; Raoult, D.; Lagier, J-C; Fabre, A title: Child with liver transplant recovers from COVID-19 infection. The hepatic anicteric cholestasis and cytolysis of our patient was probably due to her transplant state, as no hepatitis during COVID-19 infection was described in the literature [14] .
    keywords: covid-19; ebv; infection; patients
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        item: #2423 of 7819
          id: cord-281087-br4ssimq
      author: Aslan, Nagehan
       title: A Pediatric COVID19 Case with Suspected Acute Abdomen, Hyperferritinemic Sepsis and Developing MIS-C and Pancreatitis
        date: 2020-10-22
       words: 501
      flesch: 37
     summary: Elevated ferritin levels were associated with increased mortality in COVID-19 patients [4] . key: cord-281087-br4ssimq authors: Aslan, Nagehan; Yildizdas, Dincer; Sinanoglu, Muhammed Selcuk title: A Pediatric COVID19 Case with Suspected Acute Abdomen, Hyperferritinemic Sepsis and Developing MIS-C and Pancreatitis date: 2020-10-22 journal: Indian J Pediatr DOI: 10.1007/s12098-020-03544-0 sha: doc_id: 281087 cord_uid: br4ssimq nan To the Editor: Multisystem inflammatory syndrome in children (MIS-C), that develops in children due to COVID-19 is a rare but serious condition associated with COVID-19 reported in children [1] .
    keywords: children; patient
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        item: #2424 of 7819
          id: cord-281090-v3icun6z
      author: Kozlowski, Hannah N.
       title: COVID‐19: A Pandemic Experience that Illuminates Potential Reforms to Health Research
        date: 2020-09-30
       words: 2413
      flesch: 40
     summary: Together we can create a new era of medical research, where knowledge moves fluently between patients, researchers, industry, regulators and policy makers in order to generate solutions that are used in the clinic. In Toronto we previously started shifting towards patient-centred research by involving patients and families in advisory committees, ethics boards and research teams as charitable foundations have been doing for years (Stevens, 2019) .
    keywords: article; cooperation; copyright; covid-19; patients; research; researchers
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        item: #2425 of 7819
          id: cord-281099-l2i7r1bp
      author: Izzetti, Rossana
       title: A perspective on dental activity during COVID‐19: the Italian survey.
        date: 2020-08-13
       words: 3496
      flesch: 42
     summary: key: cord-281099-l2i7r1bp authors: Izzetti, Rossana; Gennai, Stefano; Nisi, Marco; Barone, Antonio; Giuca, Maria Rita; Gabriele, Mario; Graziani, Filippo title: A perspective on dental activity during COVID‐19: the Italian survey. The survey was completed by 3,254 respondents and, according to the results obtained, dental activity was reduced by the 95% and limited to urgent treatments.
    keywords: activity; article; cases; ppe; professionals; survey
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        item: #2426 of 7819
          id: cord-281102-ohbm78it
      author: Gutzeit, Andreas
       title: What can European radiologists learn from the outbreak of COVID-19 in China? A discussion with a radiologist from Wuhan
        date: 2020-04-08
       words: 1426
      flesch: 47
     summary: Patient crossing was reduced as much as possible and the distance between patients was more than 2 m. Special times were reserved in the radiology departments for possible and confirmed COVID-19 patients, if the patients could not be separated due to lack of equipment or space. We expect an enormous increase of COVID-19 patients in the next weeks and months all over the world and also in Europe.
    keywords: covid-19; outbreak; patients; radiology; wuhan
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        item: #2427 of 7819
          id: cord-281106-vzb5xzza
      author: Zerwes, S.
       title: COVID-19-Infektion – Risiko für thrombembolische Komplikationen
        date: 2020-09-01
       words: 1943
      flesch: 29
     summary: The aim of the present review article is to summarize the most relevant vascular complications in COVID-19 patients. With a rate of approximately 20%, deep vein thrombosis (DVT) of the leg is one of the most common thromboembolic events in COVID-19 patients requiring intensive care treatment.
    keywords: bei; cov-2; covid-19; der; die; eine; mit; nicht; patients; sars; syndrome; thrombosis; und; von
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        item: #2428 of 7819
          id: cord-281121-pleula62
      author: Ameer, Nasir
       title: Guillain-Barré syndrome presenting with COVID-19 infection
        date: 2020-09-14
       words: 2390
      flesch: 51
     summary: Guillain-Barré syndrome Guillain-Barré syndrome Mimics and chameleons in Guillain-Barré and Miller Fisher syndromes Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study novel coronavirus (COVID-19) outbreak: a review of the current literature Neurological complications during treatment of middle East respiratory syndrome Neurologic manifestations of hospitalized patients with coronavirus disease Neurological manifestations of COVID-19 (SARS-CoV-2): a review Guillain-Barré syndrome associated with SARS-CoV-2 infection: causality or coincidence? Guillain Barre syndrome associated with COVID-19 infection: a case report Guillain-Barré syndrome associated with SARS-CoV-2 Coronavirus statement. With the incubation period for COVID-19 respiratory symptoms believed to be up to 14 days, it is possible that neurological symptoms could develop before respiratory and other symptoms.
    keywords: barré; covid-19; guillain; infection; sars; syndrome; weakness
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        item: #2429 of 7819
          id: cord-281148-bbnbnwte
      author: Emara, Khaled
       title: What orthopedic surgeons need to know about Covid-19 pandemic()
        date: 2020-05-20
       words: 409
      flesch: 49
     summary: In this article, we provide a brief review for Orthopedic surgeons as regard COVID-19 virus microbiology, epidemiology, clinical picture, and diagnosis. It began on December Coronaviruses are enveloped single stranded RNA viruses that range between 60-140 36 nm in diameter.
    keywords: covid-19; disease
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        item: #2430 of 7819
          id: cord-281159-elwmqqqq
      author: Lv, M.
       title: Chest Computed Tomography for the Diagnosis of Patients with Coronavirus Disease 2019 (COVID-19): A Rapid Review and Meta-Analysis
        date: 2020-04-17
       words: 4795
      flesch: 51
     summary: Methods: We conducted a rapid review and meta-analysis on studies about the use of chest CT for the diagnosis of COVID-19. We comprehensively searched databases and preprint servers on chest CT for patients with COVID-19 between 1 January 2020 and 31 March 2020.
    keywords: covid-19; funder; license; medrxiv; preprint; review
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        item: #2431 of 7819
          id: cord-281175-og3myz22
      author: Tapper, Elliot B.
       title: The COVID-19 pandemic will have a long-lasting impact on the quality of cirrhosis care
        date: 2020-04-13
       words: 2678
      flesch: 38
     summary: How will COVID-19 negatively impact quality care We are only beginning to understand the impact of the pandemic on care quality. In this article, we review how COVID-19 will impact cirrhosis care.
    keywords: care; cirrhosis; covid-19; pandemic; patients; quality; risk; telehealth
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        item: #2432 of 7819
          id: cord-281185-myfuzsh7
      author: Yan, Bin
       title: China’s experience on mental health in response to the COVID-19 pandemic
        date: 2020-06-12
       words: 899
      flesch: 38
     summary: Psychological interventions for people affected by the COVID-19 epidemic Guideline for psychological assistance and social work services in designate hospital for COVID-19 The COVID-19 pandemic, personal reflections on editorial responsibility Progression of Mental Health Services during the COVID-19 Outbreak in China We express our heartfelt respect to all the people who are fighting the pandemic around the world. 2. Provide psychological support and psychological crisis intervention for healthcare workers:
    keywords: covid-19; health; patients
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        item: #2433 of 7819
          id: cord-281193-sb7kgu24
      author: Yang, Hai-Jun
       title: Re: Predictors of mortality for patients with COVID-19 pneumonia caused by SARSCoV-2: a prospective cohort study
        date: 2020-08-03
       words: 227
      flesch: 42
     summary: We hope our comments will be helpful to improve the expression and increase the quality of the paper published by Du R et al. Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study Methods for estimating the case fatality ratio for a novel, emerging infectious disease [2] . Taken together, the findings of the study reported by Du R et al are of great significance, though some possible error and inappropriate expression were found.
    keywords: covid-19
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        item: #2434 of 7819
          id: cord-281194-yafwcway
      author: Amir-Behghadami, Mehrdad
       title: Battle with COVID-19 in Iran: What lessons can be learned from the implementation of response strategies so far?
        date: 2020-05-13
       words: 1132
      flesch: 47
     summary: The blood plasma of people who have recovered from COVID-19 infection will be donated to patients to boost their immune systems. For this reason, the first action after the media provided public education on COVID-19 disease was to establish a Corona National Antivirus Headquarters chaired by the President of Iran and headed by the MOHME.
    keywords: coronavirus; covid-19; health; patients
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        item: #2435 of 7819
          id: cord-281209-gm3aaofn
      author: Seiler, Pascal
       title: Weighting bias and inflation in the time of COVID-19: evidence from Swiss transaction data
        date: 2020-09-16
       words: 4465
      flesch: 52
     summary: Using online data for prices, (Alvarez and Lein 2020) show that prices declined by more than what is suggested by the prices underlying the CPI during the lock-down in Switzerland. downward bias in consumer price indices may result from current calculation methodologies. I find that inflation was higher during the lock-down than suggested by CPI inflation.
    keywords: consumer; covid; cpi; crisis; expenditure; index; inflation; price; weights
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        item: #2436 of 7819
          id: cord-281248-z2gisufl
      author: Buonsenso, Danilo
       title: A Pediatric Strategy for the Next Phase of the SARS–CoV-2 Pandemic
        date: 2020-10-09
       words: 2974
      flesch: 37
     summary: The collaboration between experts in different fields from different countries was pivotal in writing a comprehensive manuscript on a particularly important topic on child health. (3) provide unique evidence to implement new guidelines and new routines to provide child education at school.
    keywords: children; cov-2; covid-19; health; sars; school; services
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        item: #2437 of 7819
          id: cord-281268-8yoxgmeb
      author: López-Bueno, Rubén
       title: Association Between Current Physical Activity and Current Perceived Anxiety and Mood in the Initial Phase of COVID-19 Confinement
        date: 2020-07-23
       words: 4596
      flesch: 36
     summary: Nevertheless, the analyses stratified for age and gender showed important associations between PA adherence to WHO guidelines and lower current perceived anxiety in most of the study subgroups, providing consistency to our findings (i.e. the association between current PA and current perceived anxiety and mood is widely observed across study subgroups). In addition, a borderline significant inverse association was found between current PA and current perceived worse mood when fully adjusted (OR, 0.82; 95% CI, 0.68–1.00); this association was significantly stronger in women than men.
    keywords: anxiety; confinement; covid-19; current; health; mood; study
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        item: #2438 of 7819
          id: cord-281276-rffp6qe2
      author: Rhazi, Karima El
       title: Ethical issues related to the hydroxychloroquine treatment prescription for Covid-19
        date: 2020-06-17
       words: 3416
      flesch: 43
     summary: However, one could argue that the worldwide emergency, the rapid spread of the disease, and the high rates of disease mortality mainly at the beginning of the pandemic [9] , are sufficient reasons for prescribing this off-label treatment for covid-19 patients. To date, no drugs have demonstrated safety and efficacy in randomized controlled trials for patients with COVID-19.
    keywords: covid-19; drug; evidence; hydroxychloroquine; label; patients; treatment; use
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        item: #2439 of 7819
          id: cord-281281-knelqmzx
      author: Villas-Boas, Gustavo R.
       title: The New Coronavirus (SARS-CoV-2): A Comprehensive Review on Immunity and the Application of Bioinformatics and Molecular Modeling to the Discovery of Potential Anti-SARS-CoV-2 Agents
        date: 2020-09-07
       words: 15802
      flesch: 36
     summary: Spike features determining 'host jump' of coronaviruses SARS-CoV, MERS-CoV, and beyond The spike protein of SARS-CoV-A target for vaccine and therapeutic development Cell responses to whole SARS coronavirus in Humans T-cell immunity of SARS-CoV: Implications for vaccine development against MERS-CoV Canine coronavirus highly pathogenic for dogs Experimental infection of dogs with a novel strain of canine coronavirus causing systemic disease and lymphopenia Prolonged depletion of circulating CD4+ T lymphocytes and acute monocytosis after pantropic canine coronavirus infection in dogs Canine Coronavirus: Not Only an Enteric Pathogen Molecular characterization of HLJ-073, a recombinant canine coronavirus strain from China with an ORF3abc deletion Genotypic Characterization of Canine Coronaviruses Associated with Fatal Canine Neonatal Enteritis in the United States Natural history of a recurrent feline coronavirus infection and the role of cellular immunity in survival and disease Acquisition of macrophage tropism during the pathogenesis of feline infectious peritonitis is determined by mutations in the feline coronavirus spike protein An update on canine coronaviruses: Viral evolution and pathobiology Epstein-Barr virus-Specific CD8+ T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential Decreased CCR5 expression on CD4+ T Cells of SIV-Infected sooty mangabeys Expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome Renin-angiotensin system: The unexpected flaw inside the human immune system revealed by SARS-CoV-2 Immunity after natural exposure to enteric canine coronavirus does not provide complete protection against infection with the new pantropic CB/05 strain The Thymus Is a Common Target Organ Articles Genomic characterisation and epidemiology of 2019 novel coronavirus: Implications for virus origins and receptor binding First Cases of Coronavirus Disease (COVID-19) in Brazil, South America (2 Genomes The origins of bioinformatics Multiple sequence alignment modeling: Despite little understanding about the pathophysiology and high pathogenicity of SARS-CoV-2 infection, early studies have shown that increased amounts of proinflammatory cytokines in serum (e.g., (interleukin IL) IL-1β, IL-6, IL-12, interferon-γ (IFNγ), Interferon-inducible protein 10 (IP10), and monocytic chemotactic protein 1 (MCP1)) were associated with pulmonary inflammation and extensive lung damage in patients with Severe Acute Respiratory Syndrome (SARS)
    keywords: analysis; bioinformatics; cell; compounds; coronavirus; cov-2; covid-19; data; development; drugs; figure; host; human; infection; patients; potential; proteins; receptor; sars; spike; studies; system; target; treatment
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        item: #2440 of 7819
          id: cord-281283-h6yai7sx
      author: Ma, Jun
       title: Emergency response strategy for containing COVID-19 within a psychiatric specialty hospital in the epicenter of the COVID-19 epidemic in China
        date: 2020-08-04
       words: 2196
      flesch: 32
     summary: During this isolation period, patients are screened, confirmed patients are transferred to the ward for confirmed COVID-19 patients, suspected patients are transferred to the ward for suspected COVID-19 patients, and clean (uninfected) patients are treated in this ward. (2) A ward for suspected COVID-19 patients: this ward is used for patients with negative nucleic acid test results but with clinical and imaging manifestations similar to those of COVID-19 patients; secondary protections should be implemented.
    keywords: covid-19; hospital; outbreak; patients; ward
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        item: #2441 of 7819
          id: cord-281285-5g1rw202
      author: Simonis, Alexander
       title: A comparative analysis of remdesivir and other repurposed antivirals against SARS‐CoV‐2
        date: 2020-11-03
       words: 9524
      flesch: 35
     summary: Several studies could show that entry, as shown for SARS-CoV before, depends on binding of the receptor-binding domain (RBD) (subunit S1) of the S-protein to the human angiotensin converting enzyme receptor 2 (ACE2; Hoffmann et al, 2020a; Walls et al, 2020) . intracellular release of genomic RNA Burkard et al, 2014; Ou et al, 2020) .
    keywords: activity; antiviral; cell; coronavirus; cov-2; covid-19; drugs; effects; efficacy; entry; et al; hcq; patients; rdv; replication; rna; sars; treatment; virus
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        item: #2442 of 7819
          id: cord-281361-tye5pev7
      author: Trapani, G.
       title: Children with COVID-19 like symptoms in Italian Pediatric Surgeries: the dark side of the coin
        date: 2020-07-29
       words: 3548
      flesch: 53
     summary: Later digestive symptoms, such as nausea, vomiting, abdominal pain, and diarrhea were observed in COVID-19 positive children. COVID-19 like symptoms were identified in Literature as the most common in COVID-19 positive children [14, 15, 17, 23, 24] , and defined as the presence of one of the following: fever, fatigue, rhinitis, sore throat or earache, cough, nausea or vomiting, Significance of the association between area of residence, gender, age class, symptoms and presence of suspected/confirmed cases in the family was evaluated by Fisher's exact test.
    keywords: children; covid-19; license; preprint; symptoms
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        item: #2443 of 7819
          id: cord-281376-1xdj06m7
      author: Cirilo, E. R.
       title: One Study of COVID-19 Spreading at The United States - Brazil - Colombia
        date: 2020-09-02
       words: 2347
      flesch: 54
     summary: The our simulations predict that there are some control over COVID-19 disease in theses countries, yet. Simulações Numéricas para descrever o padrão mais recente de desenvolvimento do COVID-19 nesses países, que nós observamos.
    keywords: covid-19; license; medrxiv; medrxiv preprint; preprint; review
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        item: #2444 of 7819
          id: cord-281391-0qkku2jd
      author: Miller-Handley, Hilary
       title: Treatment Options for COVID-19 in Patients with Reduced or Absent Kidney Function
        date: 2020-09-17
       words: 4721
      flesch: 41
     summary: Janssen Medical Information Face Sheet The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Clinical Features of 69 Cases with Coronavirus Disease ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells FDA Approval Summary: Tocilizumab for Treatment of Chimeric Antigen Receptor T Cell-Induced Severe or Life-Threatening Cytokine Release Syndrome Effective treatment of severe COVID-19 patients with tocilizumab Tocilizumab therapy reduced intensive care unit admissions and/or mortality in COVID-19 patients ACTEMRA® (tocilizumab) injection, for intravenous or subcutaneous use JAK-inhibitors. Corticosteroids usage in COVID-19 was originally controversial, because some data in SARS patients found no difference between steroid usage and no steroid usage in clinical outcomes; although studies were small, and mostly non-randomized [40] .
    keywords: clinical; covid-19; disease; hydroxychloroquine; patients; sars; therapy; treatment; trials
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        item: #2445 of 7819
          id: cord-281397-w7ne9mj5
      author: Leverenz, David L
       title: Is the HScore useful in COVID-19?
        date: 2020-05-05
       words: 224
      flesch: 31
     summary: key: cord-281397-w7ne9mj5 authors: Leverenz, David L; Tarrant, Teresa K title: Is the HScore useful in COVID-19? date: 2020-05-05 journal: Lancet DOI: 10.1016/s0140-6736(20)31057-6 sha: doc_id: 281397 cord_uid: w7ne9mj5 nan In a review of 191 patients with COVID-19 admitted to hospital, 3 the IQR of ferritin concentrations at time of admission in non-survivors was 728·9-2000·0 ng/mL, and the median ferritin did not exceed 2000·0 ng/mL until 16 days after symptom onset, when most patients had experienced acute respiratory distress syndrome requiring intubation. Other HScore criteria such as hypertriglyceridaemia, splenomegaly, hepatomegaly, and bone marrow haemophagocytosis are not reported in most cohort studies of COVID-19.
    keywords: covid-19
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        item: #2446 of 7819
          id: cord-281400-ho2m7nqn
      author: Nguyen, Van Thu
       title: Research response to COVID-19 needed better coordination and collaboration: a living mapping of registered trials
        date: 2020-10-21
       words: 2316
      flesch: 40
     summary: Conclusion This living mapping analysis showed that COVID-19 trials have relatively small sample size with certain redundancy in research questions. Our data are obtained from the WHO International Clinical Trials Registry Platform (ICTRP) (https://www.who.int/ictrp/en/), an international registry that assembles information on clinical trials registered in 17 primary registries (4) .
    keywords: covid-19; data; mapping; rcts; registered; research; trials
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        item: #2447 of 7819
          id: cord-281406-d7g0pbj4
      author: Chen, Yifei
       title: Epidemiological analysis of the early 38 fatalities in Hubei, China, of the coronavirus disease 2019
        date: 2020-04-24
       words: 4403
      flesch: 53
     summary: Data of COVID-19 death cases in Hubei were extracted prospectively from the website of Health Commission of Hubei province [18] and the official Weibo (China' s equivalent of Twitter) account of China Central Television news center [19] , starting from 9 January 2020, when the first deceased patient was reported, through 24 January 2020, when the 38 th was registered. Aside from viral genome studies, researchers also looked into the clinical features and epidemiologic characteristics of COVID-19 cases.
    keywords: cases; china; coronavirus; covid-19; death; disease; patients; symptoms; time
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        item: #2448 of 7819
          id: cord-281411-la8njxc1
      author: García-Fernández, Amaya
       title: Utilidad y seguridad de la automonitorización electrocardiográfica durante el tratamiento con hidroxicloroquina y azitromicina en pacientes con COVID-19
        date: 2020-10-01
       words: 1270
      flesch: 43
     summary: [[en]] Usefulness and safety of self-electrocardiographic monitoring during treatment with hydroxychloroquine and azithromycin in COVID-19 patients Amaya García-Fernández a* 4 During March and April of 2020, a study was conducted in our hospital to analyze the effect of treatment with HCQ (either alone or in combination with AZ) on the QTc and the incidence of ventricular arrhythmias in patients admitted with SARS-CoV-2 pneumonia who met the high-risk criteria for QTc prolongation (female, age░>░65 years, history of heart disease, chronic renal disease, or diabetes, or taking both medications together).
    keywords: hcq; patients; qtc
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        item: #2449 of 7819
          id: cord-281448-e1zgqqqu
      author: Billah, M. A.
       title: Reproductive number of COVID-19: A systematic review and meta-analysis based on global level evidence
        date: 2020-05-26
       words: 3105
      flesch: 45
     summary: Another important source of variation of estimated reproductive number was type of reproductive numbers considered [20] . Various researchers worldwide estimated reproductive number of COVID-19.
    keywords: license; medrxiv; number; preprint; reproductive
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        item: #2450 of 7819
          id: cord-281487-x0a9qgjs
      author: Kim, Min Young
       title: General Approach to the Clinical Care of Solid Organ Transplant Recipients with COVID-19 Infection: Management for Transplant Recipients
        date: 2020-10-29
       words: 5918
      flesch: 32
     summary: Kidney injury is common in COVID-19 patients. At autopsy of COVID-19 patients, segmental fibrin thrombosis in glomeruli was observed in renal findings [41] .
    keywords: care; covid-19; disease; infection; kidney; mortality; organ; patients; recipients; risk; sars; transplant; transplant recipients; transplantation
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        item: #2451 of 7819
          id: cord-281500-5mm1nnwv
      author: Spadera, Lucrezia
       title: Sudden olfactory loss as an early marker of COVID-19: a nationwide Italian survey
        date: 2020-08-04
       words: 3627
      flesch: 47
     summary: SOL was identified as a significant sign of infection in COVID-19 patients, mainly aged between 30 and 40 years, even in the absence of other symptoms. Additionally, findings such as an altered sense of smell or hyposmia in uncomplicated early stage COVID-19 patients should be investigated thoroughly for CNS involvement [22] .
    keywords: cases; coronavirus; covid-19; fever; olfactory; patients; sars; sol; subjects
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        item: #2452 of 7819
          id: cord-281501-ca9oxl7f
      author: Khan, Shumayila
       title: Neuropathogenesis of SARS-CoV-2 infection
        date: 2020-07-30
       words: 3218
      flesch: 34
     summary: It appears that a correlation exists between COVID-19 patients and the concomitant encephalopathy and cerebropathy observed without any obvious cause other than the viral infection. Nevertheless, hypoxic injury to the brain caused by respiratory failure in COVID-19 patients is of serious concern.
    keywords: cov-2; covid-19; patients; sars; study; virus
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        item: #2453 of 7819
          id: cord-281508-zl2url8z
      author: Pearce, N.
       title: Is death from Covid-19 a multistep process?
        date: 2020-06-03
       words: 5003
      flesch: 47
     summary: These characteristics of Covid-19 death are consistent with the multistep model of disease, a model which has primarily been used for cancer, and more recently for amyotrophic lateral sclerosis (ALS). Thus, there are some notable features of Covid-19 death which suggest that it has a markedly different relationship with age than is the case for most other severe respiratory pathogens.
    keywords: age; covid-19; death; disease; influenza; license; log; preprint
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        item: #2454 of 7819
          id: cord-281551-0aj2zwx8
      author: Schlagenhauf, Patricia
       title: Repurposing antimalarials and other drugs for COVID-19
        date: 2020-04-02
       words: 1436
      flesch: 42
     summary: key: cord-281551-0aj2zwx8 authors: Schlagenhauf, Patricia; Grobusch, Martin P.; Maier, Julian D.; Gautret, Philippe title: Repurposing antimalarials and other drugs for COVID-19 date: 2020-04-02 journal: Travel Med Infect Dis DOI: 10.1016/j.tmaid.2020.101658 sha: doc_id: 281551 cord_uid: 0aj2zwx8 nan Travel Medicine and Infectious Disease journal homepage: www.elsevier.com/locate/tmaid Editorial Repurposing antimalarials and other drugs for COVID-19 The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, now affects countries on six continents. It will not just be enough to have candidate drugs that work in vitro against SARS-CoV-2.
    keywords: antimalarials; covid-19; drugs; sars; treatment
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        item: #2455 of 7819
          id: cord-281561-r10y2sgb
      author: Tiwari, Nidhi
       title: Novel β-Coronavirus (SARS-CoV-2): Current and Future Aspects of Pharmacological Treatments
        date: 2020-08-27
       words: 6887
      flesch: 34
     summary: The drugs at present used in COVID-19 patients and ongoing clinical trials focusing on drug repurposing of various therapeutic classes of drug e.g. antiviral, anti-inflammatory and/or immunomodulatory drugs along with adjuvant/supportive care. From this review, our aim is to provide a basic overview about currently available drugsand drugs under clinical trial for COVID-19 patients.
    keywords: coronavirus; cov-2; covid-19; disease; drug; efficacy; et al; infection; novel; patients; safety; sars; studies; study; treatment
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        item: #2456 of 7819
          id: cord-281603-3308f8hm
      author: Souza, William Marciel de
       title: Epidemiological and clinical characteristics of the early phase of the COVID-19 epidemic in Brazil
        date: 2020-04-29
       words: 3886
      flesch: 43
     summary: Geospatial analysis of COVID-19 cases, demographic and socio-economic data Based on data from the first COVID-19 reports in Brazil 10 , we hypothesized that rates of incidence and testing for COVID-19 are higher in areas of higher per capita income. Overall, 10% of COVID-19 cases in Brazil were hospitalized compared to 19% in the USA 22 .
    keywords: age; brazil; cases; clinical; covid-19; disease; license; medrxiv; preprint
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        item: #2457 of 7819
          id: cord-281619-fhyamruq
      author: Burlacu, Alexandru
       title: Unpuzzling COVID-19 Prothrombotic State: Are Preexisting Thrombophilic Risk Profiles Responsible for Heterogenous Thrombotic Events?
        date: 2020-08-25
       words: 2021
      flesch: 22
     summary: Alexandru Burlacu https://orcid.org/0000-0002-3424-1588 Iolanda Valentina Popa https://orcid.org/0000-0002-0597-8839 Role of inherited thrombophilic profile on survival of patients with sepsis SARS-CoV-2 and viral sepsis: observations and hypotheses Scientific and standardization committee communication: clinical guidance on the diagnosis, prevention and treatment of venous thromboembolism in hospitalized patients with COVID-19 Evidence-based practical guidance for the antithrombotic management in patients with coronavirus disease (COVID-19) in 2020 COVID-19: coagulopathy, risk of thrombosis, and the rationale for anticoagulation Clinical management of COVID-19 Acute respiratory distress syndrome The alveolar epithelium can initiate the extrinsic coagulation cascade through expression of tissue factor Tissue factor in infection and severe inflammation Immunothrombosis in acute respiratory distress syndrome: cross talks between inflammation and coagulation Therapeutic modulation of coagulation and fibrinolysis in acute lung injury and the acute respiratory distress syndrome High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Autopsy findings and venous thromboembolism in patients with COVID-19 Postmortem examination of COVID-19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction Pulmonary arterial thrombosis in COVID-19 with fatal outcome: results from a prospective, single-center, clinicopathologic case series Catastrophic intracranial hemorrhage in two critically Ill patients with COVID-19. Additionally, unrecognized glucose-6-phosphate dehydrogenase genetic deficiency may impact venous thrombosis risk in COVID-19 patients.
    keywords: covid-19; factor; patients; risk; sars; thrombosis
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        item: #2458 of 7819
          id: cord-281638-qw5szvop
      author: Al-Tammemi, A. B.
       title: Is it Just About Physical Health? An Internet-Based Cross-Sectional Study Exploring the Psychological Impacts of COVID-19 Pandemic on University Students in Jordan Using Kessler Psychological Distress Scale
        date: 2020-05-18
       words: 5476
      flesch: 41
     summary: Hence, students with lower motivation were likely to have higher psychological distress levels. Objectives This study aimed to assess the level of psychological distress among university students in Jordan during the COVID-19 pandemic and the associated national measures.
    keywords: covid-19; distress; health; license; medrxiv; preprint; psychological; students; study
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        item: #2459 of 7819
          id: cord-281656-8anh8rhm
      author: Pata, Francesco
       title: Authors' response: Laparoscopy and COVID-19: An off-key song?
        date: 2020-07-01
       words: 1779
      flesch: 39
     summary: Despite HIVand HBV being blood-borne viruses, laparoscopic surgery is being performed in HIV and HBV patients for many years, and no clear demonstration is available of viral transmission through the pneumoperitoneum or surgical smoke. Not now during COVID-19 outbreak and not for acute care surgery and emergency colorectal surgery: a practical algorithm from a hub tertiary teaching hospital in northern Lombardy Safe management of surgical smoke in the age of COVID-19 Detecting hepatitis B virus in surgical smoke emitted during laparoscopic surgery Is surgical plume developing during routine LEEPs contaminated with high-risk HPV?
    keywords: covid-19; laparoscopy; patients; smoke; surgery
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        item: #2460 of 7819
          id: cord-281686-edpyn8fd
      author: Dalamaga, Maria
       title: 19 treatment regimens?
        date: 2020-05-08
       words: 1454
      flesch: 13
     summary: These agents could attenuate ARDS and help control SARS-CoV-2 via multiple mechanisms including: 1) inhibition of viral replication; 2) decrease of iron availability; 3) upregulation of B cells; 4) improvement of the neutralizing anti-viral antibody titer; 5) inhibition of endothelial inflammation and 6) prevention of pulmonary fibrosis and lung decline via reduction of pulmonary iron accumulation. In animal models, fibrosis and lung function decline are associated with pulmonary iron accumulation in bleomycin-induced pulmonary fibrosis (21) .
    keywords: coronavirus; covid-19; iron; patients; sars
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        item: #2461 of 7819
          id: cord-281713-3iu8qx7n
      author: Ronquillo, Jay G
       title: Using informatics to guide public health policy during the COVID-19 pandemic in the USA
        date: 2020-07-13
       words: 1989
      flesch: 38
     summary: However, effective public health solutions for COVID-19 and future pandemics will require access to interoperable public health data at all levels. Trends in cases and deaths adjusted for state populations and resource estimates are visualized in Figure 1 .
    keywords: cases; covid-19; data; deaths; health; pandemic
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        item: #2462 of 7819
          id: cord-281733-bsq0ewac
      author: Veyseh, Maedeh
       title: Left gonadal vein thrombosis in a patient with COVID-19-associated coagulopathy
        date: 2020-09-07
       words: 2468
      flesch: 38
     summary: 8 Concomitant VTE, a potential cause of unexplained deaths, has been frequently reported in COVID-19 cases. Our case emphasises the high risk of coagulopathy in COVID-19 cases, even without a severe systemic infection.
    keywords: case; covid-19; disease; patients; symptoms; thrombosis; vein
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        item: #2463 of 7819
          id: cord-281763-8eh5j5t7
      author: Levin, Amanda B.
       title: Transforming a PICU Into an Adult ICU During the Coronavirus Disease 2019 Pandemic: Meeting Multiple Needs
        date: 2020-09-15
       words: 2657
      flesch: 43
     summary: The launch team provided standard supplies, equipment, and medication lists, and PICU staff ordered and stocked the BioDome during construction. Critically ill coronavirus disease 2019 adult patients may be cared for in a PICU and care may be augmented by implementing elements of holistic, family-centered PICU practice.
    keywords: adult; biodome; care; covid-19; patients; pediatric; picu; staff; unit
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        item: #2464 of 7819
          id: cord-281804-lhnw8jx5
      author: Sonis, Jonathan D.
       title: Humanism in the Age of COVID-19: Renewing Focus on Communication and Compassion
        date: 2020-04-24
       words: 1988
      flesch: 29
     summary: As many patients will be discharged despite ongoing symptoms and -as hospital capacity constraints grow -even potentially with evidence of moderate disease, post-discharge follow-up calls, in which a staff member contacts patients by phone following ED discharge, will continue to serve multiple purposes. While video and telephonic alternatives to bedside evaluation may facilitate communication with patients while maintaining physical separation to limit healthcare worker exposure and preserve PPE, these solutions may not be as effective in older patients, who commonly have hearing and visual impairment, challenges with manual dexterity due to arthritis, and cognitive impairment, all of which impede effective use of such technology.
    keywords: care; communication; compassion; covid-19; patients; staff
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        item: #2465 of 7819
          id: cord-281870-ax5s2i6t
      author: Goerlich, Erin
       title: Prominent Longitudinal Strain Reduction of Basal Left Ventricular Segments in Patients with COVID-19
        date: 2020-09-28
       words: 1836
      flesch: 36
     summary: We hypothesized that COVID-19 patients with reduced basal LV strain would demonstrate elevated cardiac biomarkers. CONCLUSIONS AND RELEVANCE: Reduced basal LV strain is common in COVID-19 patients.
    keywords: basal; covid-19; patients; strain
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        item: #2466 of 7819
          id: cord-281875-lq015thu
      author: Daneshjou, Roxana
       title: Pernio-like eruption associated with COVID-19 in Skin of Color
        date: 2020-07-12
       words: 866
      flesch: 39
     summary: [3] [4] [5] It is not uncommon for skin disease to be misdiagnosed in patients with skin of color, which can lead to delayed care and management. Transient Livedo Reticularis Cutaneous manifestations in COVID-19: a first perspective Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases Characterization of acute acro-ischemic lesions in non-hospitalized patients: a case series of 132 patients during the COVID-19 outbreak A new vasculitis at the time of COVID-19 Acute acro-ischemia in the child at the time of COVID-19 Taylor and Kelly's Dermatology for Skin of Color Disparities in dermatology educational resources Negative SARS-CoV-2 PCR in patients with chilblain-like lesions SARS-CoV-2 endothelial infection causes COVID-19 chilblains: histopathological, immunohistochemical and ultraestructural study of 7 paediatric cases
    keywords: covid-19; patients; skin
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        item: #2467 of 7819
          id: cord-281887-b511bjdy
      author: Ribeiro, Reitan
       title: Perioperative Cancer Care in the Context of Limited Resources during the COVID-19 Pandemic: Brazilian Society of Surgical Oncology Recommendations
        date: 2020-09-26
       words: 4744
      flesch: 40
     summary: The rational use of resources to reduce the risk of surgical cancer patients being operated on during the incubation period of a corona virus infection is important in this context. We present a protocol, focused on the patients’ outcomes, for safe and rational use of resources to reduce the risk of surgical cancer patients being operated on during the virus incubation period, in the context of areas with limited resources. Discussion.
    keywords: areas; cancer; covid-19; pandemic; patients; prevalence; resources; risk; screening; surgery; testing
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        item: #2468 of 7819
          id: cord-281891-qucjw8q1
      author: Liu, Yu
       title: The effectiveness of diaphragmatic breathing relaxation training for improving sleep quality among nursing staff during the COVID-19 outbreak: a before and after study
        date: 2020-10-07
       words: 4130
      flesch: 50
     summary: key: cord-281891-qucjw8q1 authors: Liu, Yu; Jiang, Tong-tong; Shi, Tie-ying; Liu, Yong-ning; Liu, Xiu-mei; Xu, Guo-jun; Li, Fang-lin; Wang, Yue-liang; Wu, Xiao-yu title: The effectiveness of diaphragmatic breathing relaxation training for improving sleep quality among nursing staff during the COVID-19 outbreak: a before and after study date: 2020-10-07 journal: nan DOI: 10.1016/j.sleepx.2020.100026 sha: doc_id: 281891 cord_uid: qucjw8q1 Objectives Recent studies have demonstrated that first-line nurses involved in the coronavirus disease-2019 (COVID-19) crisis may experience sleep disturbances. As breathing relaxation techniques can improve sleep quality, anxiety, and depression, the current study aimed to evaluate the effectiveness of diaphragmatic breathing relaxation training (DBRT) for improving sleep quality among nurses in Wuhan, China during the COVID-19 outbreak.
    keywords: anxiety; breathing; dbrt; nurses; quality; sleep; study
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        item: #2469 of 7819
          id: cord-281922-lr3wbt21
      author: Padley, Roxanne H.
       title: COVID-19 Lockdown Learning: The Revolution of Virtual Teaching
        date: 2020-08-29
       words: 683
      flesch: 35
     summary: Indeed, despite the undoubted benefits of having a wider access to surgical demonstrations via online platforms, in the long term it is unlikely that it would be feasible for doctors and particularly surgeons in training to acquire the necessary skills without an integration of hands-on practical and clinical elements. A further valid point raised is most definitely that of security in the use of online platforms to maximise healthcare resources, the authors state the importance of safeguarding confidential information and suggest frequent updates of software.
    keywords: authors; teaching
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        item: #2470 of 7819
          id: cord-281944-5rh0v96j
      author: Hajure, Mohammedamin
       title: Depression, Anxiety and Associated Factors Among Chronic Medical Patients Amid COVID-19 Pandemic in Mettu Karl Referral Hospital, Mettu, Ethiopia, 2020
        date: 2020-10-28
       words: 3762
      flesch: 42
     summary: The pandemic is influencing mental health and causing psychological distress in the population with underlying medical conditions, especially those who have chronic medical illnesses. The COVID-19 pandemic has caused moderate to extremely severe depression (16.5%) and anxiety (25%) among people with chronic medical illness in Spain, 10 as well as 32.4% and 18.7% of moderate to severe depression in Italy and this was associated with unemployment, female gender, low educational level and medical problems.
    keywords: anxiety; covid-19; depression; illness; patients; study
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        item: #2471 of 7819
          id: cord-281945-jvnjzjds
      author: Radnis, Caitlin
       title: Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia
        date: 2020-09-06
       words: 2814
      flesch: 38
     summary: In this case series, we describe three cases of hypoxic brain injury seen on magnetic resonance imaging (MRI) in patients with hypoxemia secondary to COVID-19-related ARDS. The lack of severe observed hypoxemia in two of the cases suggests that unrecognized or asymptomatic hypoxemia may play a role in hypoxic brain injury related to COVID-19.
    keywords: acute; ards; brain; covid-19; hypoxemia; injury; patients
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        item: #2472 of 7819
          id: cord-281948-xv7vuypd
      author: Hoang, Ansel
       title: COVID-19 in 7780 pediatric patients: A systematic review
        date: 2020-06-26
       words: 4070
      flesch: 43
     summary: Compared to that review and other COVID-19 pediatric systematic reviews, [18À21] this manuscript has several key advantages: (1) we summarize 131 studies that includes 7780 children from 26 different countries, (2) this report synthesizes underlying pediatric medical conditions and delineates bacterial and viral coinfections, (3) we quantitatively describe clinical symptoms and imaging findings, (4) herein, we conglomerate the mean and standard deviation of frequently used laboratory analytes in COVID-19 positive children, (5) our report presents antiviral therapies by specific agents, and (6) our systematic review offers a preliminary comparison of patients with/without MIS-C. Although SARS-CoV-2 infection was first identified in China, the United States has now amassed the highest number of confirmed cases [18] . Statistical analyses between COVID-19 pediatric patients with/ without MIS-C was conducted on STATA v¢13.
    keywords: children; clinical; covid-19; data; disease; laboratory; mis; patients; review; studies
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        item: #2473 of 7819
          id: cord-281961-5mdiwzvc
      author: de las Heras-Pedrosa, Carlos
       title: Sentiment Analysis and Emotion Understanding during the COVID-19 Pandemic in Spain and Its Impact on Digital Ecosystems
        date: 2020-07-31
       words: 7481
      flesch: 44
     summary: Enfermedad por el Coronavirus (COVID-19) Evolution of Reported Cases, Deaths and Recovered Cases from the COVID-19 Pandemic in Spain; Ministry of Health of the Government of Spain Masks that the Spanish Government Has Distributed to Each Autonomous Community from March 10 to Government communication in the digital age: Social media's effect on local government public relations Cifras de Población (CP) a 1 de Julio de 2019 Detecting spammers on social network through clustering technique Detecting spammers on social networks Automating Visualization, Descriptive, and Predictive Statistics Using Twitter to Better Understand the Spatiotemporal Patterns of Public Sentiment: A Case Study in Massachusetts, USA IBM Watson Analytics Cloud Platform as Analytics-as-a-Service System for Heart Failure Early Detection. Trust and credibility, demonstrated through empathy, experience, honesty, and transparency, are essential elements of public health crisis communication
    keywords: communication; covid-19; crisis; emotion; government; health; information; media; pandemic; population; public; risk; shows; social
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        item: #2474 of 7819
          id: cord-281990-x5nql0cw
      author: Liu, Y.
       title: Association between epidemic dynamics of Covid-19 infection and ABO blood group types
        date: 2020-07-15
       words: 3603
      flesch: 48
     summary: In this study, total 2173 confirmed Covid-19 infection cases treated in hospitals were analyzed, and of these patients a higher population with blood group A than that of comparable population without Covid-19 infection was found. There was no significant correlation between health care expense and Covid-19 infection cases in the analyzed countries.
    keywords: blood; cases; covid-19; death; infection; type
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        item: #2475 of 7819
          id: cord-282009-a83mun7u
      author: Pundir, Hemlata
       title: Using Chou’s 5-steps rule to study pharmacophore-based virtual screening of SARS-CoV-2 Mpro inhibitors
        date: 2020-10-20
       words: 6230
      flesch: 48
     summary: After that, to screen novel compounds against COVID-19, the molecular docking of 11 screened compounds was performed with target protein Mpro using PyRx. Based on our work’s findings, we propose that these compounds can be considered as lead molecules for targeting Mpro enzyme and they can be potential SARS-CoV-2 inhibitors.
    keywords: binding; complex; complexes; compounds; cov-2; energy; ligand; mpro; pharmacophore; protein; sars; x77
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        item: #2476 of 7819
          id: cord-282026-839jc5wp
      author: Tsui, Ban C. H.
       title: Coronavirus Disease 2019: Epidemiological Factors During Aerosol-Generating Medical Procedures
        date: 2020-06-16
       words: 1087
      flesch: 35
     summary: Despite these isolation measures, extensive contamination of environmental surfaces is found in the rooms of COVID-19 patients. Available at Re-purposing a face tent as a disposable aerosol evacuation system to reduce contamination in COVID-19 patients: a simulated demonstration Beware of the second wave of COVID-19
    keywords: agmps; covid-19; environment; ifs
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        item: #2477 of 7819
          id: cord-282043-cs1oyohu
      author: Giustino, Gennaro
       title: Coronavirus and Cardiovascular Disease, Myocardial Injury, and Arrhythmia: JACC Focus Seminar
        date: 2020-10-27
       words: 1930
      flesch: -10
     summary: A survey by the European Society of Cardiology Fewer hospitalizations for acute cardiovascular conditions during the COVID-19 pandemic Dysregulation of immune response in patients with COVID-19 in Wuhan, China Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum Role of interleukin 6 in myocardial dysfunction of meningococcal septic shock Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock Effects of TNFalpha on [Ca2þ]i and contractility in isolated adult rabbit ventricular myocytes Dysregulation of intracellular calcium transporters in animal models of sepsis-induced cardiomyopathy TNF alpha receptor expression in rat cardiac myocytes: TNF alpha inhibition of L-type Ca2þ current and Ca2þ transients Drug-induced mitochondrial dysfunction and cardiotoxicity Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019 Echocardiographic findings in patients with COVID-19 with significant myocardial injury Echocardiographic findings in patients with COVID-19 pneumonia Spectrum of cardiac manifestations in COVID-19: a systematic echocardiographic study STsegment elevation in patients with Covid-19-a case series ST-elevation myocardial infarction in patients with COVID-19: clinical and angiographic outcomes Takotsubo cardiomyopathy in males with Covid-19 The variety of cardiovascular presentations of COVID-19 Fulminant COVID-19-related myocarditis in an infant Acute myocarditis associated with COVID-19 infection Myocarditis detected after COVID-19 recovery Diffuse myocardial inflammation in COVID-19 associated myocarditis detected by multiparametric cardiac magnetic resonance imaging Fulminant myocarditis due to COVID-19 Outcomes of cardiovascular magnetic resonance imaging in patients recently recovered from coronavirus disease 2019 (COVID-19) COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up: JACC State-of-the-Art Review Thromboembolic risk and anticoagulant therapy in COVID-19 patients: emerging evidence and call for action Hypoxia downregulates protein S expression Severe arterial thrombosis associated with Covid-19 infection Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Cardiovascular adverse events in patients with cancer treated with bevacizumab: a meta-analysis of more than 20 000 patients Multifaceted effects of hydroxychloroquine in human disease Acute pulmonary embolism and COVID-19 pneumonia: a random association? retrospective study Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Risk of myocardial infarction and stroke after acute infection or vaccination Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Prevalence and impact of myocardial injury in patients hospitalized with COVID-19 infection Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Acute myocardial injury in patients hospitalized with COVID-19 infection: a review Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system: celebrating the 20th anniversary of the discovery of ACE2 Host cell proteases: critical determinants of coronavirus tropism and pathogenesis The science underlying COVID-19: implications for the cardiovascular system SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS COVID-19-related myocarditis in a 21-year-old female patient Typical takotsubo syndrome triggered by SARS-CoV-2 infection Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19) Myocardial localization of coronavirus in COVID-19 cardiogenic shock Detection of viral SARS-CoV-2 genomes and histopathological changes in endomyocardial biopsies.
    keywords: acute; coronavirus; covid-19; disease; infection; injury; patients
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        item: #2478 of 7819
          id: cord-282058-it0ojdk3
      author: Yu, Yuanqiang
       title: Coronavirus Disease 2019 (COVID-19) in Neonates and Children From China: A Review
        date: 2020-05-15
       words: 7506
      flesch: 41
     summary: (COVID-19) in Zhejiang, China: an observational cohort study A case report of neonatal COVID-19 infection in China Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese center for disease control and prevention SARS-CoV-2 infection in children Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China Report of the first cases of mother and infant infections with 2019 novel coronavirus in Xinyang City Henan Province SARS-CoV-2 infection with gastrointestinal symptoms as the first manifestation in a neonate Antibodies in infants born to mothers with COVID-19 Pneumonia Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Preliminary prediction of the basic reproduction number of the Wuhan novel coronavirus 2019-nCoV Estimation of the transmission risk of the 2019-nCoV and its implication for public health interventions The progress of 2019 novel coronavirus event in China Mitigate the effects of home confinement on children during the COVID-19 outbreak Initial public health response and interim clinical guidance for the 2019 novel coronavirus outbreak -United States US emergency legal responses to novel coronavirus: balancing public health and civil liberties Emerging coronaviruses: genome structure, replication, and pathogenesis Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding A pneumonia outbreak associated with a new coronavirus of probable bat origin Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan Identifying SARS-CoV-2 related coronaviruses in malayan pangolins Genome composition and divergence of the novel coronavirus (2019-nCoV) originating in China Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2 Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding Virological assessment of hospitalized patients with COVID-2019 SARS-CoV-2 viral load in upper respiratory specimens of infected patients Pathological findings of COVID-19 associated with acute respiratory distress syndrome Emerging respiratory infections: the infectious disease pathology of SARS, MERS, pandemic influenza, and Legionella Diarrhoea may be underestimated: a missing link in 2019 novel coronavirus SARS-CoV-2 productively infects human gut enterocytes Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study What are the risks of COVID-19 infection in pregnant women? However, at least five neonates born to COVID-19 pregnant women tested positive for SARS-CoV-2 (23, 26, 27) .
    keywords: cases; children; china; coronavirus; cov-2; covid-19; disease; infection; neonates; novel; patients; sars; women
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        item: #2479 of 7819
          id: cord-282085-r3w90vg8
      author: Epperly, D. E.
       title: COVID-19 Viral Loads, Environment, Ventilation, Masks, Exposure Time, And Severity : A Pragmatic Guide Of Estimates
        date: 2020-10-05
       words: 5520
      flesch: 49
     summary: https://doi.org/10.1101/2020.10.03.20206110 doi: medRxiv preprint It has been shown in various challenge studies as noted earlier that case severity tends to increase with increasing initial exposure viral load. Future studies could improve this adjustment value.
    keywords: air; challenge; covid-19; estimates; exposure; illness; influenza; patients; study
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        item: #2480 of 7819
          id: cord-282095-cbfyydi3
      author: Pierron, Denis
       title: Smell and taste changes are early indicators of the COVID-19 pandemic and political decision effectiveness
        date: 2020-10-14
       words: 6449
      flesch: 46
     summary: Finally, a comparative study in Israel 20 showed that in COVID-19 suspected patient the frequency of smell change is almost ten time higher in a COVID-19 positive patients (68%) than in COVID-19 negative (8%). We propose that an increase in the incidence of sudden smell and taste change in the general population may be used as an indicator of COVID-19 spread in the population.
    keywords: changes; covid-19; data; france; french; lockdown; self; smell; survey; symptoms; taste; taste changes
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        item: #2481 of 7819
          id: cord-282097-a1pwq4fi
      author: Hoertel, N.
       title: Dexamethasone use and Mortality in Hospitalized Patients with Coronavirus Disease 2019: a Multicenter Retrospective Observational Study
        date: 2020-10-27
       words: 4418
      flesch: 36
     summary: key: cord-282097-a1pwq4fi authors: Hoertel, N.; Sanchez, M.; Vernet, R.; Beeker, N.; Neuraz, A.; Alvarado, J.; Daniel, C.; Paris, N.; Gramfort, A.; Lemaitre, G.; Salamanca, E.; Bernaux, M.; Bellamine, A.; Burgun, A.; Limosin, F. title: Dexamethasone use and Mortality in Hospitalized Patients with Coronavirus Disease 2019: a Multicenter Retrospective Observational Study date: 2020-10-27 journal: nan DOI: 10.1101/2020.10.23.20218172 sha: doc_id: 282097 cord_uid: a1pwq4fi Objective: To examine the association between dexamethasone use and mortality among hospitalized patients for COVID-19. In this group of patients, there was a significant association between dexamethasone use and reduced mortality in both the crude, unadjusted analysis (hazard ratio (HR), 0.40; 95% CI, 0.18 to 0.87, p=0.021) and the adjusted multivariable analysis (HR, 0.46; 95% CI, 0.22 to 0.96, p=0.039).
    keywords: covid-19; dexamethasone; medrxiv; patients; preprint; support
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        item: #2482 of 7819
          id: cord-282131-wap7lo05
      author: Chen, Haixia
       title: Clinical and imaging features of COVID-19
        date: 2020-04-27
       words: 3386
      flesch: 43
     summary: [6] specifically formulated clinical diagnosis standards for patients in Hubei Province, and defined suspected cases with pneumonia imaging manifestations as clinical diagnostic cases, which reduced the risk of further spread. The central distribution of the lesion is different from the characteristic subpleural distribution of new coronavirus pneumonia.
    keywords: coronavirus; covid-19; diagnosis; disease; imaging; patients; pneumonia
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        item: #2483 of 7819
          id: cord-282142-76jr4p7n
      author: Wang, Yun
       title: Potential Effect of COVID-19 on Maternal and Infant Outcome: Lesson From SARS
        date: 2020-08-07
       words: 5514
      flesch: 38
     summary: Arch Dis Childh Fetal Neonatal Ed Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome SARS in newborns and children Clinical analysis of pregnancy in second and third trimesters complicated severe acute respiratory syndrome A case-controlled study comparing clinical course and outcomes of pregnant and non-pregnant women with severe acute respiratory syndrome SARS and pregnancy: a case report SARS during pregnancy, United States Severe acute respiratory syndrome in pregnancy Infants born to mothers with severe acute respiratory syndrome The placentas of patients with severe acute respiratory syndrome: a pathophysiological evaluation Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia Single-cell RNAsequencing analysis identifies host long noncoding RNA MAMDC2-AS1 as a co-factor for HSV-1 nuclear transport A pregnant woman with COVID-19 in Central America Detection of specific antibodies to severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein for serodiagnosis of SARS coronavirus pneumonia Clinical features of patients infected with 2019 novel coronavirus in Wuhan A novel coronavirus from patients with pneumonia in china Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding What are the risks of COVID-19 infection in pregnant women? Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Potential maternal and infant outcomes from (Wuhan) coronavirus 2019-nCoV infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections Clinical characteristics of 2019 novel coronavirus infection in China Coronaviridae Study Group of the International Committee on Taxonomy of Viruses.
    keywords: coronavirus; cov-2; covid-19; infection; maternal; patients; pregnancy; sars; transmission; women
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        item: #2484 of 7819
          id: cord-282183-k0pn0ie2
      author: Spiezia, Luca
       title: More severe hypercoagulable state in acute COVID-19 pneumonia as compared to other pneumonia.
        date: 2020-10-01
       words: 1727
      flesch: 33
     summary: The results of our study show that COVID-19 patients admitted to medical wards for acute pneumonia had markedly hypercoagulable profiles on whole blood thromboelastometrycompared to COVID-19 negative patients with pneumonia -mainly -in a group of patients consecutively admitted to Internal Medicine wards of Padova University Hospital for acute pneumonia: cases were COVID-19 patients with pneumonia and controls were patients with pneumonia from different etiology.
    keywords: acute; covid-19; patients; pneumonia
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        item: #2485 of 7819
          id: cord-282197-hkt7nktc
      author: Frisullo, Giovanni
       title: Stroke integrated care pathway during COVID-19 pandemic
        date: 2020-06-03
       words: 964
      flesch: 35
     summary: A team consisting of internists, cardiologists, neurologists, and infectious disease specialists guarantees a multidisciplinary approach to s-COVID-19 stroke patients subjected to multiparametric monitoring of vital parameters. key: cord-282197-hkt7nktc authors: Frisullo, Giovanni; De Belvis, Antonio Giulio; Marca, Giacomo Della; Angioletti, Carmen; Calabresi, Paolo title: Stroke integrated care pathway during COVID-19 pandemic date: 2020-06-03 journal: Neurol Sci DOI: 10.1007/s10072-020-04480-9 sha: doc_id: 282197 cord_uid: hkt7nktc nan We read with a great interest the publication on Acute stroke management pathway during Coronavirus-19 pandemic [1] where Baracchini et al. shared their experience in the management of stroke patients in a COVID-19 Hospital.
    keywords: covid-19; patients; stroke
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        item: #2486 of 7819
          id: cord-282198-ugmv9om1
      author: Pare, Joseph R.
       title: Point-of-care Lung Ultrasound Is More Sensitive than Chest Radiograph for Evaluation of COVID-19
        date: 2020-06-19
       words: 3411
      flesch: 48
     summary: Further work may find LUS for the evaluation and care of COVID-19 patients to be of clinical benefit and may also have a role to guide testing as screening and contact tracing are expanded. acr.org/Advocacy-and-Economics/ACR-Position-Statements/ Recommendations-for-Chest-Radiography-and-CT-for-Suspected-COVID19-Infection Frequency and distribution of chest radiographic findings in COVID-19 positive patients Accuracy of lung ultrasonography versus chest radiography for the diagnosis of adult community-acquired pneumonia: review of the literature and meta-analysis Can lung US help critical care clinicians in the early diagnosis of novel coronavirus (COVID-19) pneumonia? Findings of lung ultrasonography of novel corona virus pneumonia during the 2019-2020 epidemic A preliminary study on the ultrasonic manifestations of peripulmonary lesions of non-critical novel coronavirus pneumonia (COVID-19) Diagnosing acute heart failure in the emergency department: a systematic review and metaanalysis Guidelines for Reporting Diagnostic Accuracy Studies: explanation and elaboration Relevance of lung ultrasound in the diagnosis of acute respiratory failure: the BLUE protocol What's new in lung ultrasound during the COVID-19 pandemic Transforming growth factor beta-1 as a predictor of fibrosis in tuberculous pleurisy Pulmonary imaging of pandemic influenza H1N1 infection: relationship between clinical presentation and disease burden on chest radiography and CT A coefficient of agreement for nominal scales
    keywords: covid-19; cxr; findings; lines; lus; patients
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        item: #2487 of 7819
          id: cord-282202-q2q4vies
      author: Banerjee, Amitava
       title: Clinical academic research in the time of Corona: A simulation study in England and a call for action
        date: 2020-08-13
       words: 4111
      flesch: 41
     summary: Dissemination: across UK and internationally to those considering COVID-19 clinical research. key: cord-282202-q2q4vies authors: Banerjee, Amitava; Katsoulis, Michail; Lai, Alvina G.; Pasea, Laura; Treibel, Thomas A.; Manisty, Charlotte; Denaxas, Spiros; Quarta, Giovanni; Hemingway, Harry; Cavalcante, João L.; Noursadeghi, Mahdad; Moon, James C. title: Clinical academic research in the time of Corona: A simulation study in England and a call for action date: 2020-08-13 journal: PLoS One DOI: 10.1371/journal.pone.0237298 sha: doc_id: 282202 cord_uid: q2q4vies OBJECTIVES:
    keywords: academic; clinical; covid-19; data; health; infection; mitigation; model; number; pandemic; research
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        item: #2488 of 7819
          id: cord-282219-7kzbnymp
      author: Wu, Liu
       title: The effect of massage on the quality of life in patients recovering from COVID-19: A systematic review protocol
        date: 2020-06-05
       words: 2458
      flesch: 46
     summary: [15] Massage therapy is characterized by the excellent therapeutic effect on analgesia, no side effect, easy to operate, low economic burden, and more beneficial to promote patients to recovery. We will include articles related to massage therapy of patients recovering from COVID-19.
    keywords: analysis; coronavirus; covid-19; data; massage; patients; quality; review
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        item: #2489 of 7819
          id: cord-282256-lqmixm7s
      author: Tsioufis, Costas
       title: The interplay of Hypertension, ACE-2 and SARS-CoV-2: Emerging data as the “Ariadne’s thread” for the “labyrinth” of COVID-19
        date: 2020-05-22
       words: 1850
      flesch: 40
     summary: In 2020, humanity is facing one of the most devastating health urgencies in known modern history leading to health system collapse, economies shutting down, unemployment surges and thousands of deaths worldwide due to COVID-19 infection. 10, 11 Concerning the heart and vascular component of COVID-19 infection, dysregulation of the ACE-2 related pathways are linked to cardiac muscle injury and potential hemodynamic collapse.
    keywords: aceis; angiotensin; arbs; covid-19; hypertension; patients
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        item: #2490 of 7819
          id: cord-282261-wcmc5mh6
      author: Rhodus, Elizabeth K.
       title: COVID-19 and geriatric clinical trials research
        date: 2020-09-16
       words: 2258
      flesch: 31
     summary: Further, older adults are substantially underrepresented in clinical trials research, and this situation may worsen this discrepancy. Attention to clinical trial development with special attention to need for inclusion of older adults and precautions is greatly needed to sustain current efforts, at minimum, and ideally, enhance recognition of the value of including older adults in clinical trial research.
    keywords: adults; covid-19; need; participants; research; safety; trials
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        item: #2491 of 7819
          id: cord-282268-f7mbdfr6
      author: Cartenì, Armando
       title: How mobility habits influenced the spread of the COVID-19 pandemic: Results from the Italian case study
        date: 2020-06-24
       words: 5280
      flesch: 32
     summary: Within this topic, the aim of the paper was to quantify the effect of mobility habits in the spread of the Coronavirus in Italy through a multiple linear regression model. Estimation results showed that mobility habits represent one of the variables that explains the number of COVID-19 infections jointly with the number of tests/day and some environmental variables (i.e. PM pollution and temperature).
    keywords: cases; covid-19; day; e.g.; habits; mobility; number; time
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        item: #2492 of 7819
          id: cord-282312-h3h6vw5l
      author: Greco, Antonio
       title: Outcomes of renin–angiotensin–aldosterone system blockers in patients with COVID-19: a systematic review and meta-analysis
        date: 2020-07-16
       words: 873
      flesch: 46
     summary: 5 However, available studies have limited statistical power to detect signals of increased mortality. It has been hypothesized that the use of ACEIs/ARBs may negatively impact on the clinical outcomes of COVID-19 patients by affecting the expression of angiotensinconverting enzyme 2 aminopeptidase (ACE-2), the human receptor for SARS-CoV-2.
    keywords: arbs; covid-19; studies
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        item: #2493 of 7819
          id: cord-282339-a1ln2v2p
      author: Pinto, Daniel
       title: The role of breast FNA during and post‐ COVID‐19 pandemic: a fast and safe alternative to needle core biopsy
        date: 2020-07-23
       words: 1909
      flesch: 44
     summary: We would invite the reader to challenge their preconceptions of breast FNABs: not only have ancillary tests have been shown to be viable on both smears and cell blocks but, in 2019, the Yokohama System for Reporting Breast Fine‐Needle Aspiration Biopsy Cytopathology was developed and validated, enabling an accurate and reproducible categorization of breast lesions, significantly reducing the need for follow‐up CNBs. (23) However, FNABs of breast lesions have a long history in western medicine, and their diagnostic value cannot be understated.
    keywords: article; breast; covid-19; lesions; pandemic
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        item: #2494 of 7819
          id: cord-282355-urys21ry
      author: Ortega-Quijano, Daniel
       title: Reply to “Varicella-like exanthem as a specific COVID-19-associated skin manifestation: multicenter case series of 22 patients”: discussing specificity
        date: 2020-05-04
       words: 556
      flesch: 42
     summary: This type of study would calculate the association of COVID-19 status (yes/no) with the type of exanthem (varicella-like/non varicella-like) in a predetermined number of patients (to ensure sufficient statistical power) and in a defined population with a known prevalence of COVID-19 disease. This gives varicella-like rash additional COVID-19 positive predictive value compared to the rest of the rashes.
    keywords: covid-19; varicella
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        item: #2495 of 7819
          id: cord-282361-gje78nb1
      author: Gökce, Mehmet İlker
       title: How does the COVID-19 pandemic affect the preoperative evaluation and anesthesia applied for urinary stones? EULIS eCORE–IAU multicenter collaborative cohort study
        date: 2020-05-20
       words: 3250
      flesch: 40
     summary: Regarding the unexpected and underestimated involvement of the world as well as modern medicine with COVID-19 pandemic in a truly unprepared status; many questions arose with respect to preoperative patient evaluation, as there was no standard approach and/or recommendations during problematic days. Also no alterations in method of anesthesia or stone related intervention was reported related to COVID-19 pandemic.
    keywords: anesthesia; covid-19; days; evaluation; patients; stone
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        item: #2496 of 7819
          id: cord-282371-39qo9afy
      author: Khulood, Daulat
       title: Convalescent plasma appears efficacious and safe in COVID-19
        date: 2020-09-28
       words: 3098
      flesch: 45
     summary: Epub ahead of print 15 National Library of Medicine (US) Early safety indicators of COVID-19 convalescent plasma in 5,000 patients Safety update: COVID-19 convalescent plasma in 20,000 hospitalized patients EMPADE study: evaluation of medical prescriptions and adverse drug events in COPD patients admitted to intensive care unit Use of convalescent plasma therapy in two COVID-19 patients with acute respiratory distress syndrome in Korea Treatment with convalescent plasma for COVID-19 patients in Wuhan Treatment of 5 critically ill patients with COVID-19 with convalescent plasma Treatment with convalescent plasma for critically ill patients with SARS-CoV-2 infection. A total of eight studies conducted on CP therapy in patients with COVID-19 were reviewed wherein 25,028 patients above 18 years of age were involved.
    keywords: convalescent; covid-19; patients; plasma; sars; therapy; treatment
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        item: #2497 of 7819
          id: cord-282384-qbcqbhk4
      author: Savastano, Alfonso
       title: Peripapillary Retinal Vascular Involvement in Early Post-COVID-19 Patients
        date: 2020-09-08
       words: 3745
      flesch: 39
     summary: According to our results, post-COVID-19 patients have a lower RPCP PD and a normal RPCP FI compared to the general population. According to our results, post-COVID-19 patients have a lower RPCP PD and a normal RPCP FI compared to the general population.
    keywords: covid-19; group; patients; peripapillary; post; rpcp; sars; thickness
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        item: #2498 of 7819
          id: cord-282402-1skkjes1
      author: Blumenthal-Barby, Jennifer
       title: Payment of COVID-19 challenge trials: underpayment is a bigger worry than overpayment
        date: 2020-10-12
       words: 1381
      flesch: 45
     summary: Grimwade et al have the opposite concern-that researchers will underpay challenge trial participants. In sum, these data raise significant concerns about underpayment, exploitation and unfair treatment of challenge trial participants.
    keywords: challenge; participants; trials
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        item: #2499 of 7819
          id: cord-282409-gnphco0f
      author: Ozaras, Resat
       title: Coinfections among COVID-19 patients: A Need for Combination Therapy?
        date: 2020-08-18
       words: 650
      flesch: 37
     summary: Accumulating data suggest that influenza coinfection is undiagnosed and underestimated and is likely to associate with a higher mortality. Although influenza is decreasing during this pandemic because of the measures, clinicians should keep alert COVID-19 patients with influenza coinfection.
    keywords: covid-19; influenza
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        item: #2500 of 7819
          id: cord-282411-n5xlpqms
      author: Wang, Huali
       title: Dementia care during COVID-19
        date: 2020-03-30
       words: 1189
      flesch: 48
     summary: Older people in many countries, unlike in China, tend to live alone or with their spouse, either at home or in nursing homes. To lessen the chance of infection among older people in nursing homes, more local authorities are banning visitors to nursing homes and longterm care facilities.
    keywords: covid-19; dementia; people
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        item: #2501 of 7819
          id: cord-282416-5x3lyuuf
      author: Adams, Hugo J.A.
       title: Chest CT imaging signature of COVID-19 infection: in pursuit of the scientific evidence
        date: 2020-06-25
       words: 4157
      flesch: 45
     summary: None of these studies described sufficient details of the patients who underwent chest CT at different time points to understand potentially confounding factors on the temporal course of chest CT findings (such as pulmonary comorbidities and therapies that were administered), time points of chest CT imaging during the course of disease were dissimilar between all studies, and all studies provided mere descriptive data without performing comprehensive statistical analyses to assess for differences in chest CT findings between different time points. Furthermore, one study compared different patients who underwent chest CT at different time points rather than evaluating the time course of chest CT findings in the same patients.
    keywords: chest; covid-19; disease; findings; imaging; patients; studies
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        item: #2502 of 7819
          id: cord-282430-u5ukqc5z
      author: Fenton, Mark E.
       title: An Expanded COVID-19 Telemedicine Intermediate Care Model Using Repurposed Hotel Rooms
        date: 2020-10-15
       words: 2175
      flesch: 31
     summary: Not only do patients who are positive for COVID-19 and are convalescing after acute care hospital admission transition there, but appropriate subacute patients identified in dedicated COVID-19 assessment centers and emergency rooms can also enter intermediate care according to established criteria (Table 1) . The Alveolar Recruitment Trial showed us that systematically performed recruitment maneuvers, known to cause alveolar overdistention, increased mortality rate in patients with acute respiratory distress syndrome (ARDS) (2) .
    keywords: care; covid-19; model; overdistention; patients; peep
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        item: #2503 of 7819
          id: cord-282458-5v9k4yyj
      author: Balakrishnan, Vijayakumar
       title: Screening of FDA Approved Drugs Against SARS-CoV-2 Main Protease: Coronavirus Disease
        date: 2020-09-28
       words: 2366
      flesch: 48
     summary: key: cord-282458-5v9k4yyj authors: Balakrishnan, Vijayakumar; Lakshminarayanan, Karthik title: Screening of FDA Approved Drugs Against SARS-CoV-2 Main Protease: Coronavirus Disease date: 2020-09-28 journal: Int J Pept Res Ther DOI: 10.1007/s10989-020-10115-6 sha: doc_id: 282458 cord_uid: 5v9k4yyj At the end of December 2019, a new strain of coronavirus was identified in the Wuhan city of Hubei province in China. For this, the complete list of FDA approved drugs (~ 1500 compounds) were retrieved from the Binding Database (BindingDB).
    keywords: covid-19; drugs; glide; site
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        item: #2504 of 7819
          id: cord-282460-z7g3uikr
      author: Guillo, Enora
       title: COVID-19 pneumonia: Diagnostic and prognostic role of CT based on a retrospective analysis of 214 consecutive patients from Paris, France
        date: 2020-08-08
       words: 2487
      flesch: 46
     summary: A review of typical CT findings and differential diagnosis Coronavirus Disease 2019 (COVID-19): A Systematic Review of Imaging Findings in 919 Patients Evolution of CT findings in patients with mild COVID-19 pneumonia Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases Diagnostic Performance of CT and Reverse Transcriptase-Polymerase Chain Reaction for Coronavirus Disease 2019: Following binary logistic regression analysis, only comorbidities (p=0.003) and CT disease extent (p=0.008) were independently associated to death/intubation.
    keywords: covid-19; disease; patients; pneumonia; symptoms
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        item: #2505 of 7819
          id: cord-282499-baia5prj
      author: Lei, Pinggui
       title: The evolution of CT characteristics in the patients with COVID-19 pneumonia
        date: 2020-03-19
       words: 441
      flesch: 35
     summary: key: cord-282499-baia5prj authors: Lei, Pinggui; Fan, Bing; Yuan, Yingnan title: The evolution of CT characteristics in the patients with COVID-19 pneumonia date: 2020-03-19 journal: J Infect DOI: 10.1016/j.jinf.2020.03.014 sha: doc_id: 282499 cord_uid: baia5prj nan In that study, significant statistical differences were observed in CT features of peripheral involving central ( P = 0.028), consolidation ( P = 0.009), and thickened interlobular septa ( P = 0.040) between moderate ( n = 28) and sever/critically severe ( n = 13). Therefore, knowing the corresponding CT feature of COVID-19 pneumonia at different stages, which could be helpful to precisely diagnose and understand CT characteristics of the novel coronavirus pneumonia beyond the radiological findings itself.
    keywords: covid-19
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        item: #2506 of 7819
          id: cord-282504-m3npy0om
      author: Kastritis, Efstathios
       title: Challenges in the Management of patients with systemic light chain (AL) amyloidosis during the COVID‐19 pandemic
        date: 2020-06-01
       words: 4648
      flesch: 37
     summary: The use of ACE inhibitors or angiotensin-receptor blockers is limited in amyloidosis patients due to poor tolerance, but data do not support their discontinuation specifically for COVID-19(Hanff, et al 2020 , Vaduganathan, et al 2020 . The ISA drives an initiative to collect data of amyloidosis patients with COVID-19; ASH is also gathering data for patients with hematologic diseases and COVID-19, including patients with AL amyloidosis.
    keywords: 2020; amyloidosis; covid-19; et al; infection; patients; risk; therapy
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        item: #2507 of 7819
          id: cord-282513-hbqo5ylv
      author: Park, Hyunbong
       title: Mental Healthcare Policies in South Korea during the COVID-19 Epidemic
        date: 2020-06-16
       words: 1398
      flesch: 40
     summary: This could ultimately support the recovery of mental health throughout the entire community by discovering high-risk mental health groups early and providing timely treatment intervention. Since stigmatization not only hinders the discovery of infectious agents, it can also directly lead to social isolation and mental health problems; social efforts to avoid stigmatization will be essential.
    keywords: anxiety; covid-19; health; people
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        item: #2508 of 7819
          id: cord-282526-b8tky324
      author: Berger Gillam, T.
       title: Norwich COVID-19 Testing Initiative: feasibility project evaluation
        date: 2020-09-23
       words: 2802
      flesch: 51
     summary: This study aimed to pilot mass COVID-19 testing on a university research park, to assess the feasibility and acceptability of scaling up to all staff and students. The study did not identify any false positives, despite this being considered a risk of universal testing (10) .
    keywords: covid-19; participants; population; preprint; students; study; testing; university
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        item: #2509 of 7819
          id: cord-282528-g1cpd2hg
      author: Zobairy, H.
       title: Association of olfactory dysfunction with hospitalization for COVID-19: a multicenter study in Kurdistan
        date: 2020-07-28
       words: 3492
      flesch: 44
     summary: 7, 8 OD may be the first symptom of COVID-19 in up to a quarter of COVID-19 patients. Herein, we report the results of a multicenter study of COVID-19 patients who presented to 13 hospitals across the Kurdistan province of Iran.
    keywords: covid-19; disease; license; medrxiv; patients; preprint
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        item: #2510 of 7819
          id: cord-282530-55lhjfm8
      author: Carsana, Luca
       title: Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy: a two-centre descriptive study
        date: 2020-06-08
       words: 3436
      flesch: 34
     summary: The predominant pattern of lung lesions in patients with COVID-19 patients is diffuse alveolar damage, as described in patients infected with severe acute respiratory syndrome and Middle East respiratory syndrome coronaviruses. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV Pulmonary pathology of severe acute respiratory syndrome in Toronto Histopathology of Middle East respiratory syndrome coronavirus (MERS-CoV) infection-clinicopathological and ultrastructural study Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China COVID-19 autopsies Pathological findings of COVID-19 associated with acute respiratory distress syndrome Histopathologic changes and SARS-CoV-2 immunostaining in the lung of a patient with COVID-19 Pulmonary pathology of early-phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer Management of the corpse with suspect, probable or confirmed COVID-19 respiratory infection-Italian interim recommendations for personnel potentially exposed to material from corpses, including body fluids, in morgue structures and during autopsy practice Lung pathology of severe acute respiratory syndrome (SARS): a study of 8 autopsy cases from Singapore Megakaryocytes and platelet homeostasis in diffuse alveolar damage The intracellular sites of early replication and budding of SARS-coronavirus Immunohistochemical, in situ hybridization, and ultrastructural localization of SARS-associated coronavirus in lung of a fatal case of severe acute respiratory syndrome in Taiwan Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Anticoagulant therapy in acute respiratory distress syndrome Thromboembolic risk and anticoagulant therapy in COVID-19 patients: emerging evidence and call for action SARScoronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
    keywords: cases; covid-19; damage; diffuse; features; lung; patients; sars
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        item: #2511 of 7819
          id: cord-282535-gnuhjs32
      author: Cook, Gordon
       title: Real‐world assessment of the clinical impact of symptomatic infection with severe acute respiratory syndrome coronavirus (COVID‐19 disease) in patients with Multiple Myeloma receiving systemic anti‐cancer therapy.
        date: 2020-05-21
       words: 1302
      flesch: 42
     summary: A disproportionate level of COVID-19 related mortality is noted in patients of Afro-Caribbean origin in our cohort ( Figure 1C ) compared to Caucasian patients but extreme caution is advised in relation to over interpreting this data given the actual low numbers of patients of non-Caucasian origin (n=10) reported in this audit despite the prevalence of MM(10) . This coupled with a median age at presentation of 70 years in a population with frequent co-existing medical conditions, means the outcomes of MM patients infected with COVID-19 warrants particular attention.
    keywords: covid-19; median; myeloma; patients
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        item: #2512 of 7819
          id: cord-282571-ilf73g71
      author: Ni, Wentao
       title: Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19
        date: 2020-07-13
       words: 5443
      flesch: 39
     summary: Cloning and functional expression as a captopril-insensitive carboxypeptidase ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation Angiotensinconverting enzyme 2 is a functional receptor for the SARS coronavirus Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2 Structure of SARS coronavirus spike receptor-binding domain complexed with receptor Trilogy of ACE2: a peptidase in the renin-angiotensin system, a SARS receptor, and a partner for amino acid transporters Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Structure, function, and evolution of coronavirus spike proteins Surface vimentin is critical for the cell entry of SARS-CoV Clathrindependent entry of severe acute respiratory syndrome coronavirus into target cells expressing ACE2 with the cytoplasmic tail deleted Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. ACE2 is associated with multi-organ injury in COVID-19 Autopsies of SARS patients showed that SARS-CoV infection can cause injury to multiple organs, such as the heart, kidney, liver, skeletal muscle, central nervous system, and adrenal and thyroid glands, besides the lungs
    keywords: ace2; acute; angiotensin; cells; coronavirus; cov-2; covid-19; injury; patients; receptor; sars
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        item: #2513 of 7819
          id: cord-282572-j14izwxd
      author: Tasnim, S.
       title: Epidemiology of sleep disorders during COVID-19 pandemic: A systematic scoping review
        date: 2020-10-11
       words: 7711
      flesch: 45
     summary: key: cord-282572-j14izwxd authors: Tasnim, S.; Rahman, M.; Pawar, P.; Chi, X.; Yu, Q.; Zou, L.; Sultana, A.; McKyer, E. L. J.; Ma, P.; Hossain, M. M. title: Epidemiology of sleep disorders during COVID-19 pandemic: A systematic scoping review date: 2020-10-11 journal: nan DOI: 10.1101/2020.10.08.20209148 sha: doc_id: 282572 cord_uid: j14izwxd Background: A growing burden of mental health problems has become a global concern amid the coronavirus disease (COVID-19) pandemic. Sleep disorders are major mental health problems associated with increased psychosocial stressors; however, no research synthesis is available on the epidemiology of it.
    keywords: covid-19; disorders; health; insomnia; license; medrxiv; pandemic; preprint; review; sleep; studies
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        item: #2514 of 7819
          id: cord-282589-xof56j98
      author: Lopes, M. I. F.
       title: Beneficial effects of colchicine for moderate to severe COVID-19: an interim analysis of a randomized, double-blinded, placebo controlled clinical trial
        date: 2020-08-11
       words: 3973
      flesch: 50
     summary: Clinical trials with larger numbers of patients should be conducted to further evaluate the efficacy and safety of colchicine as an adjunctive therapy for hospitalized patients with moderate to severe COVID-19. Clinical trials with larger numbers of patients should be conducted to further evaluate the efficacy and safety of colchicine as an adjunctive therapy for hospitalized patients with moderate to severe COVID-19. .
    keywords: colchicine; covid-19; day; days; group; patients; placebo; treatment
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        item: #2515 of 7819
          id: cord-282598-ghh16h43
      author: Dattilo, Wesley
       title: COVID-19 most vulnerable Mexican cities lack the public health infrastructure to face the pandemic: a new temporally-explicit model
        date: 2020-04-14
       words: 4702
      flesch: 47
     summary: Currently, Mexican cities with more infection cases (i.e., Mexico City, Guadalajara, and Monterrey) have some of the largest and most active international airports in the country, being hubs for both international and domestic flights. In addition to modeling how the COVID-19 will spread across the Mexican territory over time, we consider of crucial importance to know if Mexican cities are prepared with the required healthcare infrastructure to successfully deal with this pandemic under the simulated scenarios.
    keywords: cities; covid-19; license; medrxiv; medrxiv preprint; model; preprint
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        item: #2516 of 7819
          id: cord-282620-nv2tg68j
      author: Hinz, S.
       title: Internet-based tool for visualizing county and state level COVID-19 trends in the United States.
        date: 2020-05-18
       words: 1661
      flesch: 57
     summary: The interactive map of the US allows users to visualize the distribution of confirmed COVID-19 infections (Figure 1 ) with plots for summary statistics, data transformations, and trends for the US. Our rolling slope function is an easily digestible method of evaluating changes in direction and rate of confirmed COVID-19 infections and deaths over time.
    keywords: data; license; preprint; state
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        item: #2517 of 7819
          id: cord-282633-q7egnpaq
      author: Singh, Ashish Kumar
       title: COVID‐19: Assessment of knowledge and awareness in Indian society
        date: 2020-08-27
       words: 2312
      flesch: 45
     summary: Factor analysis with principal component analysis was used to describe the unobserved underlying latent variables with 12 observed variables (items) of prevention methods adopted by people for coronavirus. The objective of factor analysis was to know that what are the major ways through which people's were preventing themselves from virus Table 5 .
    keywords: analysis; coronavirus; covid-19; pandemic; people; study
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        item: #2518 of 7819
          id: cord-282660-9x937eus
      author: Muñoz Vives, Josep Maria
       title: Mortality Rates of Patients with Proximal Femoral Fracture in a Worldwide Pandemic: Preliminary Results of the Spanish HIP-COVID Observational Study
        date: 2020-05-06
       words: 3219
      flesch: 45
     summary: Variables are described for the total number of included patients and separately for the number of patients who survived and those who had died. Variables are reported for the total number of included patients and also separately for the patients who survived and those who died.
    keywords: covid-19; fracture; hip; hospitals; mortality; patients; rate; study
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        item: #2519 of 7819
          id: cord-282675-s4zmffj3
      author: Sagaon-Teyssier, Luis
       title: Assessment of mental health outcomes and associated factors among workers in community-based HIV care centers in the early stage of the COVID-19 outbreak in Mali
        date: 2020-10-15
       words: 6933
      flesch: 43
     summary: RAND Corporation Poor performance of community health workers in Kalabo District Staff attrition among community health workers in home-based care programmes for people living with HIV and AIDS in western Kenya Health workers, quality of care, and child health: Simulating the relationships between increases in health staffing and child length Focussing on the wellbeing of health care workers in sub-Saharan Africa Overworked? The deleterious impact on HCW mental health [14, 15] because of the these structural problems and unpreparedness to contain COVID-19 constitutes a serious public health issue [16] .
    keywords: anxiety; care; centers; covid-19; depression; hcw; health; healthcare; hiv; insomnia; mali; mental; outbreak; workers
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        item: #2520 of 7819
          id: cord-282687-483ojkbb
      author: Purcino, Flávia Abranches Corsetti
       title: Management of benign and suspicious breast lesions during the coronavirus disease pandemic: recommendations for triage and treatment
        date: 2020-06-24
       words: 1822
      flesch: 35
     summary: While individualization of each case is encouraged, there is clear guidance to perform abscess or infection surgeries after conservative management failure and to postpone other benign breast disease surgeries for at least 3 months. Resource for Management Options of Breast Cancer During COVID-19 Statement on COVID-19 -Advice for Surgical Oncologists on Cancer Service Provision Considerac¸ões sobre opc¸ões de manejo de neoplasias durante a pandemia de COVID-19 Colégio Brasileiro de Radiologia (ACR) e Federac¸ão Brasileira das Associac¸ões de Ginecologia e Obstetrícia (FEBRASGO) sobre as orientac¸ões para agendamento dos exames de imagem da mama durante a pandemia de COVID-19 Vias livres de COVID-19 Recommendations for prioritization, treatment, and triage of breast cancer patients during the COVID-19 pandemic.
    keywords: breast; cancer; covid-19; health; pandemic; patients
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        item: #2521 of 7819
          id: cord-282699-tuas2tgd
      author: LIU, Wei-hong
       title: Understanding of guidance for acupuncture and moxibustion interventions on COVID-19 (Second edition) issued by CAAM
        date: 2020-03-17
       words: 2984
      flesch: 49
     summary: Moxibustion therapy: Moxibustion is applied by the patient him/herself at ST36, PC6, LI4, CV6, CV4, SP6, etc., about 10 min at each acupoint. The authors believe that for moxibustion interventions, the mild moxibustion with hand-holding moxa stick is not suggested.
    keywords: acupuncture; cases; china; covid-19; disease; guidance; interventions; moxibustion; treatment
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        item: #2522 of 7819
          id: cord-282704-qg2o0ug4
      author: Li, Xun
       title: Clinical characteristics of 25 death cases infected with COVID-19 pneumonia: a retrospective review of medical records in a single medical center, Wuhan, China
        date: 2020-02-25
       words: 2258
      flesch: 55
     summary: Malnutrition was common to severe patients. All the patients' albumin levels and 80% and 68% of patients' RBC and Hb levels were decreased, which indicates that malnutrition is common to severe patients.
    keywords: covid-19; levels; medrxiv; patients; preprint
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        item: #2523 of 7819
          id: cord-282721-bxg9zqyu
      author: Bandyopadhyay, G.
       title: Let us unite against COVID-19 – a New Zealand perspective
        date: 2020-05-14
       words: 2185
      flesch: 48
     summary: A record 1.9 billion NZD was allocated to mental health over a period of 5 years with the aim of integrating mental health services and *Address for correspondence: Dr Gargi Bandyopadhyay, Whanganui Hospital, 100 Heads Road, Whanganui, 4500, New Zealand. Governmentfunded health services are free to New Zealanders (Ministry of Health New Zealand, 2017).
    keywords: care; covid-19; government; health; new; services; zealand
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        item: #2524 of 7819
          id: cord-282724-zzkqb0u2
      author: Moore, Jason H.
       title: Ideas for how informaticians can get involved with COVID-19 research
        date: 2020-05-12
       words: 7598
      flesch: 28
     summary: These are organized under sub-disciplines for biomedical informatics including Bioinformatics that focuses on basic science questions, Clinical Informatics that focuses on the delivery of healthcare, Clinical Research Informatics that focuses on research using clinical data, Consumer Health Informatics that focuses on the use of mobile devices and telemedicine, and Public Health informatics that focuses on research questions at the population or community level. Secure informatics platforms such as Integrating Bench to Bedside (i2b2) and the Shared Health Research Information Network (SHRINE), Trinetix, and Atlas play an important role in standardizing and harmonizing clinical data to common data models (CDMs) including i2b2, Patient-Centered Outcomes Research Network (PCORnet), Fast Healthcare Interoperability Resource (FHIR), and Observational Medical Outcomes Partnership (OMOP).
    keywords: analysis; cov-2; covid-19; data; disease; efforts; health; healthcare; informatics; models; pandemic; patients; public; research; researchers; sars; social; testing; tools
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        item: #2525 of 7819
          id: cord-282726-deisqgmw
      author: Bashir, Mohamad
       title: Cardiovascular Disease and Surgery Amid COVID-19 Pandemic
        date: 2020-04-28
       words: 1064
      flesch: 42
     summary: Trends 9 Immunol Population Diversity and Collective Interactions during Influenza Virus 11 Infection Are patients with hypertension and diabetes mellitus at 13 increased risk for COVID-19 infection? Clinical features of patients infected 15 with 2019 novel coronavirus in Wuhan, China Endothelial Cell Dysfunction and the Pathobiology of 17 Clinical and 19 virological data of the first cases of COVID-19 in Europe: a case series Procalcitonin to 22 initiate or discontinue antibiotics in acute respiratory tract infections Surviving Sepsis 2 Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 3 2019 (COVID-19) Clinical characteristics of 113 deceased patients with coronavirus disease 5 2019: retrospective study Reports summed it up to a group of affected patients who were vendors or dealers at the 23 local Huanan Seafood market.
    keywords: covid-19; disease; patients
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        item: #2526 of 7819
          id: cord-282730-pawasfh4
      author: Contreras, Carlo M.
       title: Telemedicine: Patient-Provider Clinical Engagement During the COVID-19 Pandemic and Beyond
        date: 2020-05-08
       words: 3570
      flesch: 40
     summary: This waiver also established equivalent reimbursement for video telemedicine visits and traditional in-person visits. At many institutions, the number of telemedicine visits dramatically increased within days following the institution of novel coronavirus pandemic restrictions on in-person clinical encounters.
    keywords: care; covid-19; data; pandemic; patients; telehealth; telemedicine; use; video; visits
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        item: #2527 of 7819
          id: cord-282732-qym6wji7
      author: McLaughlin, Katie-May
       title: COVID-19-Related Coagulopathy—Is Transferrin a Missing Link?
        date: 2020-07-30
       words: 2931
      flesch: 40
     summary: Free Radic Transferrin plays a central role in coagulation balance by interacting with clotting factors The emerging spectrum of cardiopulmonary pathology of the coronavirus disease 2019 (COVID-19): Report of 3 autopsies from Houston, Texas, and review of autopsy findings from other United States cities Iron metabolism and lymphocyte characterisation during Covid-19 infection in ICU patients: An observational cohort study Transferrin synthesis by inducer T lymphocytes Regulation of transferrin gene expression during lung development and injury Iron metabolism in the lower respiratory tract Regulation of the tissue-specific expression of transferrin gene Adipose Tissue Transferrin and Insulin Resistance Transferrin isoforms in cerebrospinal fluid and their relation to neurological diseases Iron-Deficiency and Estrogen Are Associated with Ischemic Stroke by Up-Regulating Transferrin to Induce Hypercoagulability COVID-19: Linear models were generated to estimate the relationship between gene expression and age using the base R function lm, which generated p-values indicating the significance of the relationship.
    keywords: age; covid-19; expression; females; males; sars; transferrin
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        item: #2528 of 7819
          id: cord-282736-1sc19r5m
      author: Marengoni, Alessandra
       title: The impact of delirium on outcomes for older adults hospitalised with COVID-19
        date: 2020-08-20
       words: 1902
      flesch: 34
     summary: None. Delirium: a missing piece in the COVID-19 pandemic puzzle Delirium in elderly people Neurobiology of COVID-19 Delirium in hospitalized older adults Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China Neurologic features in severe SARS-CoV-2 infection Clinical presentation of COVID19 in dementia patients National French survey of COVID-19 symptoms in people aged 70 and over Validation of the 4AT, a new instrument for rapid delirium screening: a study in 234 hospitalised older people Diagnostic and Statistical Manual of Mental Disorders 5th ed Assessing and measuring chronic multimorbidity in the older population: a proposal for its operationalization A global clinical measure of fitness and frailty in elderly people Delirium day: a nationwide point prevalence study of delirium in older hospitalized patients using an easy standardized diagnostic tool Neurological features of COVID-19 and their treatment: a review Nervous system involvement after infection with COVID-19 and other coronaviruses Neuroinfection may potentially contribute to pathophysiology and clinical manifestations of COVID-19 Brain MRI findings in severe COVID-19: a retrospective observational study Delirium, dementia, and in-hospital mortality: the results from the Italian delirium day 2016, a National Multicenter Study Association between delirium superimposed on dementia and mortality in hospitalized older adults: a prospective cohort study Collaborative delirium prevention in the age of COVID-19 Delirium is a frequent condition in hospitalized older patients and it usually has a negative prognostic value.
    keywords: covid-19; delirium; hospital; patients
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        item: #2529 of 7819
          id: cord-282737-xa4ct4lf
      author: Müller, Simon M.
       title: National Publication Productivity during the COVID-19 Pandemic—A Preliminary Exploratory Analysis of the 30 Countries Most Affected
        date: 2020-09-05
       words: 3294
      flesch: 39
     summary: We also found a clear correlation between GDP and the publication rates for both COVID-19 and non-COVID-19 publications, but interestingly, only weak positive correlations between R&D investment (as percentage of GDP) and non-COVID-19 publication rate, but not with that of COVID-19 publications. The Spearman's correlation coefficients resulting from correlations between the COVID-19, nonCOVID-19 (i.e., publications on Cancer, Diabetes and Stroke published between 1 January and 30 April 2020 and pre-COVID-19 publication rates (i.e., publications on Cancer, Diabetes and Stroke published between 1 January and 30 April 2020) with the factors listed in Table 1 are shown in Figure 1 (exact p-values in Table A1 ).
    keywords: care; countries; covid-19; health; publication; rate
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        item: #2530 of 7819
          id: cord-282753-uw3r6q45
      author: Goldberg-Stein, Shlomit
       title: Abdominopelvic CT findings in patients with novel coronavirus disease 2019 (COVID-19)
        date: 2020-08-06
       words: 3762
      flesch: 36
     summary: The rate of positive abdominopelvic CT findings in COVID-positive patients remains unknown. Lower hemoglobin, younger age and male gender were independent predictors of having positive abdominopelvic CT findings.
    keywords: abdominopelvic; covid-19; disease; findings; patients; study; symptoms
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        item: #2531 of 7819
          id: cord-282780-34j7gquo
      author: Lai, Kevin E.
       title: Tele-Neuro-Ophthalmology During the Age of COVID-19
        date: 2020-06-26
       words: 6301
      flesch: 41
     summary: The level of urgency dictates the type of visits available to the patient (e.g., in-person examination, video telemedicine visit, phone telemedicine visit, and interprofessional consultation) and the timeframe for management. If one seeks full integration of appointment scheduling, EHR, telemedicine visits, electronic medication orders, and patient portal communication, other platforms (e.g., AmWell, NextGen, and Zipnosis) offer more comprehensive services.
    keywords: care; content; covid-19; health; ipad; neuro; ophthalmology; patient; platform; services; telemedicine; testing; use; video; visit
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        item: #2532 of 7819
          id: cord-282814-wnc9iql3
      author: Armstrong, A.
       title: A plastic surgery service response to COVID-19 in one of the largest teaching hospitals in Europe
        date: 2020-04-21
       words: 1858
      flesch: 51
     summary: 15 , 16 Non-clinical roles are being filled by more junior clinical students, such as assisting with quantitative Polymerase Chain Reaction (qPCR) testing for COVID-19 and helping with administrative or logistical tasks. In order to increase the capacity of clinical staff, medical students who have passed their final exams and prescribing safety assessment, are being asked to work as 'F0s' within the Trust.
    keywords: cases; covid-19; leadership; patients; staff
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        item: #2533 of 7819
          id: cord-282825-svgknqud
      author: Ramaswamy, Swathi Beladakere
       title: COVID-19 in Refractory Myasthenia Gravis- A Case Report of Successful Outcome
        date: 2020-06-02
       words: 1748
      flesch: 38
     summary: Treatment of MG patients with COVID-19 needs to be tailored to individual patient. Treatment of MG patients with COVID-19 needs to be tailored to individual patient.
    keywords: covid-19; infection; myasthenia; patient
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        item: #2534 of 7819
          id: cord-282839-3ii79g6j
      author: Moreno-Fernández Ayala, Daniel J.
       title: Age-related mitochondrial dysfunction as a key factor in COVID-19 disease
        date: 2020-11-07
       words: 10253
      flesch: 20
     summary: Further, T cell exhaustion associated with dendritic cell dysfunction has been also associated with the immunopathology of COVID-19 (Zheng et al., 2020a , Zheng et al., 2020b and an active role of local SARS-CoV-2 infected neutrophils and macrophages in inflammatory reactions has been recently proposed (Jafarzadeh et al., 2020) . This chronic inflammation has been associated with the inhibition of antigen-specific immunity and the low response of aged people to vaccines (Akbar and Gilroy, 2020; Parmigiani et al., 2013) .
    keywords: activation; activity; age; aging; autophagy; cells; coq; covid-19; diseases; dysfunction; et al; inflammation; levels; metabolic; mitochondrial; patients; proinflammatory; response; system
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        item: #2535 of 7819
          id: cord-282862-kve6fa49
      author: Pastick, Katelyn A
       title: A Systematic Review of Treatment and Outcomes of Pregnant Women with COVID-19 – A Call for Clinical Trials
        date: 2020-08-13
       words: 3317
      flesch: 39
     summary: We then evaluated the proportion of COVID-19 clinical trials (from Clinicaltrials.gov) excluding pregnant or breastfeeding persons (both through June 29(th), 2020). A second search was conducted to identify COVID-19 clinical trials as of June 29th, 2020 that reported pregnancy/breastfeeding as an exclusion criterion.
    keywords: breastfeeding; covid-19; outcomes; pregnancy; studies; trials; women
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        item: #2536 of 7819
          id: cord-282867-kbyxdegu
      author: Shah, Sayed Zulfiqar Ali
       title: Scaling the Need, Benefits, and Risks Associated with COVID-19 Acute and Postacute Care Rehabilitation: A Review
        date: 2020-08-26
       words: 4550
      flesch: 35
     summary: Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents Rehabilitation Research and Practice Impact of severe acute respiratory syndrome (SARS) on pulmonary function, functional capacity and quality of life in a cohort of survivors Six month radiological and physiological outcomes in severe acute respiratory syndrome (SARS) survivors A major outbreak of severe acute respiratory syndrome in Hong Kong Rehabilitation and respiratory management in the acute and early post-acute phase Pathogenesis and natural history of osteonecrosis Avascular necrosis of bone in severe acute respiratory syndrome Steroidinduced osteonecrosis in severe acute respiratory syndrome: a retrospective analysis of biochemical markers of bone metabolism and corticosteroid therapy Chest physiotherapy for pneumonia in adults Chest physiotherapy in primary pneumonia Epidemiology and outcome of acute respiratory failure in intensive care unit patients Effects of sputum on pulmonary function A randomised controlled trial of the effectiveness of an exercise training program in patients recovering from severe acute respiratory syndrome Pulmonary rehabilitation for patients with coronavirus disease 2019 (COVID-19) Acute care physiotherapy management of COVID-19 patients in Qatar: consensus-based recommendations A randomized evaluation of the acute efficacy, acceptability and tolerability of flutter and active cycle of breathing with and without postural drainage in non-cystic fibrosis bronchiectasis Endotracheal suction in intubated critically ill adult patients undergoing mechanical ventilation: a systematic review Chest physiotherapy in mechanically ventilated patients without pneumonia-a narrative review Chest physical therapy for children hospitalised with acute pneumonia: a randomised controlled trial Long-term comparative trial of two different physiotherapy techniques; postural drainage with percussion and autogenic drainage, in the treatment of cystic fibrosis Efficacy and safety of early prone positioning combined with HFNC or NIV in moderate to severe ARDS: a multi-center prospective cohort study Respiratory physiotherapy in patients with COVID-19 infection in acute setting: a position paper of the Italian Association of Respiratory Physiotherapists (ARIR) According to consensus-based acute care physiotherapy recommendations developed in Qatar, rehabilitation patients could be categorized into the following six categories: Category A (paralyzed, ventilated, and sedated), Category B (ventilated and minimally sedated), Category C (no mechanical ventilation), Category C.1 (bedridden but minimally conscious), Category C.2 (conscious and active but dependent), and Category C.3 (independent, active, and conscious).
    keywords: acute; chest; coronavirus; covid-19; patients; physiotherapy; pneumonia; rehabilitation; sars; syndrome; techniques; treatment
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        item: #2537 of 7819
          id: cord-282868-yd7pzcbz
      author: Shelmerdine, Susan C.
       title: Coronavirus disease 2019 (COVID-19) in children: a systematic review of imaging findings
        date: 2020-06-18
       words: 5709
      flesch: 47
     summary: Future works on the study of COVID-19 imaging findings could be improved by the use of standardised detailed descriptors for imaging findings (i.e. stating both the pattern and localisation of findings), in line with RSNA guidance [44] , with clearly stated indications for imaging where possible. In 5/22 (22.7%) studies, a combination of both chest radiography and CT imaging findings were described [25-27, 29, 32] .
    keywords: articles; cases; children; coronavirus; covid-19; findings; imaging; infection; studies
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        item: #2538 of 7819
          id: cord-282899-kp114q7n
      author: Biswas, Saurav
       title: Blood clots in COVID-19 patients: Simplifying the curious mystery
        date: 2020-11-06
       words: 2503
      flesch: 26
     summary: key: cord-282899-kp114q7n authors: Biswas, Saurav; Thakur, Vikram; Kaur, Parneet; Khan, Azhar; Kulshrestha, Saurabh; Kumar, Pradeep title: Blood clots in COVID-19 patients: Simplifying the curious mystery date: 2020-11-06 journal: Med Hypotheses DOI: 10.1016/j.mehy.2020.110371 sha: doc_id: 282899 cord_uid: kp114q7n The universal phenomenon of blood clotting is well known to be protective in external cellular/ tissue injury. The mechanism of blood clotting is like a two-edged sword, wherein the case of severe external injury, clotting is very crucial for preventing the blood loss, whereas, in the case of internal blood vessels injury, it, unfortunately, leads to the formation of blood clots, causing vascular blockades and thrombosis, expanding to every organ leading to severe and fatal outcomes.
    keywords: blood; cov-2; covid-19; patients; sars
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        item: #2539 of 7819
          id: cord-282913-sw4enfkk
      author: Jain, Parul
       title: Manifestations in Neonates Born to COVID-19 Positive Mothers
        date: 2020-06-05
       words: 496
      flesch: 52
     summary: Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical characteristics of 19 neonates born to mothers with COVID-19 A case of 2019 novel coronavirus in a pregnant woman with preterm delivery Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia A case report of neonatal COVID-19 infection in China Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China. However, two authors reported positive SARS-CoV-2 infection in neonates born to COVID-19 positive mother [5, 6] .
    keywords: baby; covid-19
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        item: #2540 of 7819
          id: cord-282925-efkb8hc7
      author: Braidotti, R.
       title: “We” Are In This Together, But We Are Not One and the Same
        date: 2020-08-25
       words: 3277
      flesch: 48
     summary: The power of viral formations has become manifest in the pandemic, stressing the agency of non-human forces and the overall importance of Gaia as a living, symbiotic planet. Many lives today are the object of biopower's thanato-politics, doomed to ethnic cleansing or slaughter, to being killed without their killer being held accountable.
    keywords: humans; life; lives; living; non; posthuman; world
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        item: #2541 of 7819
          id: cord-282927-jhma20de
      author: Mondal, Chittaranjan
       title: Mitigating the transmission of infection and death due to SARS-CoV-2 through non-pharmaceutical interventions and repurposing drugs
        date: 2020-09-28
       words: 3035
      flesch: 51
     summary: The Lancet Infectious Diseases Treatment of COVID-19: old tricks for new challenges Analysis and forecast of COVID-19 spreading in China, Italy and France Mathematical modeling of COVID-19 transmission dynamics with a case study of Wuhan Healthcare impact of COVID-19 epidemic in India: A stochastic mathematical model Estimation of the final size of the second phase of coronavirus epidemic by the logistic model Estimations of the coronavirus epidemic dynamics in South Korea with the use of SIR model Prediction on Covid-19 epidemic for different countries: Focusing on South Asia under various precautionary 427 measures. With these assumptions, we propose the following model for Covid-19 epidemic: Those who are critically ill are assumed, for simplicity, to be unable to spread the infection further.
    keywords: covid-19; epidemic; model
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        item: #2542 of 7819
          id: cord-282956-f7if9e5q
      author: Yaghi, Shadi
       title: SARS2-CoV-2 and Stroke in a New York Healthcare System
        date: 2020-05-26
       words: 2892
      flesch: 35
     summary: We compared the clinical characteristics of stroke patients with a concurrent diagnosis of COVID-19 to stroke patients without COVID-19 (contemporary controls). Our study also shows that the number of COVID-19 positive ischemic strokes has increased initially but seems to have peaked and then decreased.
    keywords: acute; controls; covid-19; disease; patients; stroke; study
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        item: #2543 of 7819
          id: cord-282958-9bi6pobg
      author: Ganem, Fabiana
       title: The impact of early social distancing at COVID-19 Outbreak in the largest Metropolitan Area of Brazil.
        date: 2020-04-08
       words: 1678
      flesch: 47
     summary: The copyright holder for this preprint . confirmed COVID-19 cases between 26 th February and 30 th March. To tackle the spread of disease, a range of interventions have been implemented in China, including increasing test capacity, rapid isolation of suspected and confirmed cases and their contacts, social distancing measures, as well as restricting mobility (6) .
    keywords: cases; covid-19; license; preprint
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        item: #2544 of 7819
          id: cord-282963-p04c5nn7
      author: Oliveros, Estefania
       title: Rapid Deterioration of Hospital-Acquired COVID-19 in a Patient on Extracorporeal Left Ventricular Assist Support
        date: 2020-09-21
       words: 1066
      flesch: 41
     summary: First, this case underscores the rapidity of deterioration in COVID-19 patients once hypoxia starts. First, this case underscores the rapidity of deterioration in COVID-19 patients once hypoxia starts.
    keywords: asymptomatic; case; covid-19; patients
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        item: #2545 of 7819
          id: cord-282964-dmc8mlxu
      author: Wathore, Roshan
       title: Understanding air and water borne transmission and survival of coronavirus: Insights and way forward for SARS-CoV-2
        date: 2020-08-04
       words: 3368
      flesch: 22
     summary: Such type of probable routes of transmissions should be thoroughly researched for virus transmission and survival in these mediums as these possibilities may aggravate the problem to community transmissions (Heller et al., 2020) . Therefore, fomite transmission would depend on the surface characteristics, which can affect virus survival and can help determine extent of spread of the disease.
    keywords: coronavirus; covid-19; sars; surfaces; transmission; virus
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        item: #2546 of 7819
          id: cord-282982-dc5m81bx
      author: Rouillard, Smita
       title: COVID-19: Long-term Planning for Procedure-based Specialties During Extended Mitigation and Suppression Strategies
        date: 2020-05-18
       words: 2864
      flesch: 23
     summary: Given varying degrees of mitigation and suppression may persist for 1-2 years, there is a critical need for pragmatic approaches for reopening procedural and surgical units, addressing backlogs, and establishing standards of care which balance patient risk and benefit, while maintaining the procedural volumes needed for patient care during this time of ongoing disease control measures. Higher risk patients include FIT positive patients who are approaching six months from their test (after which there is a significantly increased risk of disease progression) 9-12 ; symptomatic patients (e.g. dysphagia, weight loss, gastrointestinal bleeding, inflammatory bowel disease flare, etc.); laboratory abnormalities suggestive of acute disease (e.g. acute or progressive iron deficiency anemia, abnormal imaging, obstructive jaundice, etc.); and patients with large or incompletely resected polyps.
    keywords: care; covid-19; disease; mitigation; patients; procedures; risk; suppression
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        item: #2547 of 7819
          id: cord-282990-qb4wk4yb
      author: Chen, Zhuo
       title: Safety considerations in the bioanalytical laboratories handling specimens from coronavirus disease 2019 patients
        date: 2020-08-21
       words: 1973
      flesch: 41
     summary: No viral RNA was detected from serum in the mild or severe cohort, which may represent the majority of COVID-19 patient samples. Therefore, bioanalysis of COVID-19 patient samples, including both respiratory specimens and nonrespiratory specimens, should be performed in a BSL-2 laboratory [8] .
    keywords: blood; cov-2; covid-19; patients; sars; specimens
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        item: #2548 of 7819
          id: cord-283037-hykf28oi
      author: Ortmann, Regina
       title: COVID-19 and investor behavior()
        date: 2020-08-08
       words: 2602
      flesch: 51
     summary: key: cord-283037-hykf28oi authors: Ortmann, Regina; Pelster, Matthias; Wengerek, Sascha Tobias title: COVID-19 and investor behavior() date: 2020-08-08 journal: Financ Res Lett DOI: 10.1016/j.frl.2020.101717 sha: doc_id: 283037 cord_uid: hykf28oi How do retail investors respond to the outbreak of COVID-19? •We investigate trading patterns of retail investors during the outbreak of COVID-19.
    keywords: covid-19; increase; investors; outbreak; pandemic; trading
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        item: #2549 of 7819
          id: cord-283048-hyjzofps
      author: Steele, Edward J.
       title: Origin of new emergent Coronavirus and Candida fungal diseases—Terrestrial or cosmic?
        date: 2020-07-14
       words: 7536
      flesch: 51
     summary: It suggests, first, massive region-wide physical contamination with potentially trillions of infective COVID-19 viral particles in central China-contaminating buildings, roadways, cars and factory equipment, vegetation, surface water pools, people (and their clothes, body parts such as hair, skin, personal affects, mobile phone, keys, wallets, etc.) as well as wild and domestic animals, etc. The Lancet On the origins of a species: What might explain the rise of Candida auris Candida auris: A Review of the Literature Simultaneous emergence of multidrug-resistant Candida auris on 3 continents confirmed by whole-genome sequencing and epidemiological analyses Genomic characterisation and epidemiology of 2019 novel coronavirus: Implications for virus origins and receptor binding.
    keywords: auris; candida; china; covid-19; disease; et al; fall; human; new; particles; spread; time; virus; wickramasinghe; wuhan
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        item: #2550 of 7819
          id: cord-283052-x9tek77a
      author: Stramare, Roberto
       title: Radiological management of COVID-19: structure your diagnostic path to guarantee a safe path
        date: 2020-06-04
       words: 1732
      flesch: 35
     summary: As demonstrated in the literature, radiological imaging plays a crucial role in the assessment of COVID-19 patients starting from the early phases of the disease but we should not focus only on the contribution of specific techniques or the typical signs of the infection at imaging. In fact, during the first month of the pandemic in the Regione Veneto, in our hospital, 1946 CT scans were performed, 69 of which using the mobile device (i.e., for COVID-19-positive patients), and 539 with the academic scanner (i.e., for suspected COVID-19, COVID-19 patients who could have not been transported to the truck, and non-COVID-19 patients referring to the academic unit).
    keywords: covid-19; patients; unit
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        item: #2551 of 7819
          id: cord-283059-lq0pqmcv
      author: Schwarzkopf, Ran
       title: The Response of An Orthopedic Department and Specialty Hospital at the Epicenter of a Pandemic: The NYU Langone Health Experience
        date: 2020-04-20
       words: 1945
      flesch: 47
     summary: 58 All of our sites have seen an influx of COVID patients, including Bellevue hospital which is the 59 flagship hospital for the New York City public hospital system. At the graduate medical education (GME) level, NYU initially sought to minimize house staff 165 involvement with COVID patients by creating new non-teaching pulmonology and critical care 166 teams in the hospital.
    keywords: covid; department; orthopedic; patients; surgery
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        item: #2552 of 7819
          id: cord-283065-c22zpwr8
      author: Banerjee, Indrajit
       title: The changing pattern of COVID-19 in Nepal: A Global concern- A Narrative Review
        date: 2020-06-30
       words: 4717
      flesch: 60
     summary: On comparison of the various medians of age as well as age cohorts of deaths due to COVID-19 it is apparent that data from Nepal shows a much higher attrition rate in the lower age group than it does in the elderly. A combination of Keywords was used COVID 19, OR Coronavirus, OR SARS-CoV-2 OR Mortality OR Death OR Age OR World OR Global AND Nepal Inclusion/Exclusion Criteria All of the research articles that were incorporated into the study were of the English language and was original research, published between January 25, 2020 and June 20, 2020; which focused on the age and the mortality of COVID-19 positive cases, and was focused on countries viz.
    keywords: age; cases; covid-19; deaths; nepal; patients; years
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        item: #2553 of 7819
          id: cord-283093-9kz7387z
      author: Quaife, Matthew
       title: The impact of COVID-19 control measures on social contacts and transmission in Kenyan informal settlements
        date: 2020-10-05
       words: 5615
      flesch: 49
     summary: In this study, we collect contact data from residents of informal settlements around Nairobi, Kenya, to assess if control measures have changed contact patterns, and estimate the impact of changes on the basic reproduction number (R(0)). 3 Age-stratified mean number of reported contacts from survey respondents recruited from five informal settlements around Nairobi.
    keywords: age; contacts; control; covid-19; data; household; kenya; measures; respondents; study; transmission
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        item: #2554 of 7819
          id: cord-283099-nhz3pye2
      author: Wang, Xue
       title: Unprotected mothers and infants breastfeeding in public amenities during the COVID-19 pandemic
        date: 2020-07-21
       words: 2357
      flesch: 39
     summary: This creates a dilemma for facilities lacking natural ventilation such as public lactation rooms. Efforts should also be put in improving the design of public lactation rooms, including the provision of adequate areas and emergency ventilation facilities.
    keywords: air; breastfeeding; infants; lactation; public
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        item: #2555 of 7819
          id: cord-283116-ib5c3lbi
      author: Koh, David
       title: Occupational health responses to COVID‐19: What lessons can we learn from SARS?
        date: 2020-05-13
       words: 3394
      flesch: 52
     summary: coronavirus, COVID-19, health care, occupational health, outbreaks, public health, SARS-CoV-2 confirmed cases and over 62 000 deaths spread over 200 countries and territories. Other than health care workers, anyone who are physically present or associated with health care institutions were at high risk of infection by SARS-CoV. Worldwide, HCWs comprised a significant 21% of all SARS patients, but in countries such as Canada and Singapore, more than 40% of the patients were HCWs.
    keywords: care; coronavirus; covid-19; disease; hcws; health; sars; workers
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        item: #2556 of 7819
          id: cord-283120-hyzk59qv
      author: Sharma, Ashish
       title: Liver disease and outcomes among COVID-19 hospitalized patients- a systematic review and meta-analysis
        date: 2020-10-16
       words: 2636
      flesch: 38
     summary: Future studies should evaluate changing levels of biomarkers amongst liver disease patients to predict poor outcomes of COVID-19 and causes of liver injury during COVID-19 infection. In severe acute respiratory syndrome (SARS) epidemic 60% of patients had hepatic injury, due to phylogenetic similarities of the viruses it is assumed that COVID-19 is associated with acute liver injury.
    keywords: covid-19; disease; injury; liver; outcomes; patients; study
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        item: #2557 of 7819
          id: cord-283138-18q23z8l
      author: Balasubramanian, S.
       title: Coronavirus Disease 2019 (COVID-19) in Children - What We Know So Far and What We Do Not
        date: 2020-04-09
       words: 3468
      flesch: 40
     summary: COVID-19 IN CHILDREN children [19] . I COVID-19 IN CHILDREN children with COVID-19 are likely to need any specific therapy other than supportive treatment, and the decision to start antiviral or immunomodulatory treatment should therefore be made carefully in consultation with experts in pediatric infectious disease and immunology.
    keywords: adults; cases; children; coronavirus; covid-19; disease; infection; patients; sars
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        item: #2558 of 7819
          id: cord-283152-wav0d0ws
      author: Patel, Sanjay K. S.
       title: Deploying Biomolecules as Anti-COVID-19 Agents
        date: 2020-06-09
       words: 3099
      flesch: 46
     summary: Initially, the screening of COVID-19 infection has done through measurements of temperature and related symptoms. The antibody test targets the production of antibodies such as IgA, IgM, and IgG in response to COVID-19 infection in blood samples, which takes around 14 days after infection or needs to wait for the onset of symptoms.
    keywords: cases; china; coronavirus; cov-2; covid-19; covs; human; infection; sars; transmission
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        item: #2559 of 7819
          id: cord-283173-s3nb11je
      author: Osman, Jennifer
       title: Rapid screening of COVID‐19 patients by White blood cells scattergrams, a study on 381 patients
        date: 2020-06-15
       words: 1385
      flesch: 41
     summary: (2) (3) (4) Complementary tools are warranted to increase the sensitivity of the initial testing of COVID-19 patients. During this outbreak, we have noticed a recurrent atypical aspect on the WDF of COVID-19 patients.
    keywords: covid-19; patients; wdf
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        item: #2560 of 7819
          id: cord-283175-kh2rm2ir
      author: Roma, Paolo
       title: How to Improve Compliance with Protective Health Measures during the COVID-19 Outbreak: Testing a Moderated Mediation Model and Machine Learning Algorithms
        date: 2020-10-04
       words: 7574
      flesch: 35
     summary: In this vein, the present study sought to explore the relationship between civic engagement (specifically, civic attitudes), perceived efficacy, self-efficacy, and compliance with protective health measures during the COVID-19 pandemic. In this vein, the present study sought to explore the relationship between civic engagement (specifically, civic attitudes), perceived efficacy, self-efficacy, and compliance with protective health measures during the COVID-19 pandemic.
    keywords: behaviors; compliance; covid-19; efficacy; health; health measures; measures; perception; research; risk; self
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        item: #2561 of 7819
          id: cord-283177-qwinggg4
      author: Viswanathan, Ramaswamy
       title: Support Groups and Individual Mental Health Care via Video Conferencing for Frontline Clinicians during the COVID-19 Pandemic
        date: 2020-06-23
       words: 2893
      flesch: 52
     summary: We hope that peer group support and individual interventions like these will help protect the mental health of a number of clinicians who are doing such commendable and courageous work, so that they can continue to effectively help the countless severely ill patients with COVID-19. From late March 2020, our department of psychiatry began offering support group and individual video-conference sessions to help our frontline attending physicians, resident physicians, nurses and other healthcare professionals, and students.
    keywords: groups; health; physicians; sessions; support; work
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        item: #2562 of 7819
          id: cord-283196-laerx0n2
      author: Bedford, Juliet
       title: Living with the COVID-19 pandemic: act now with the tools we have
        date: 2020-10-08
       words: 1696
      flesch: 30
     summary: COVID-19 vaccines, therapeutics, and diagnostics are important for the pandemic response, and if any of the COVID-19 vaccine candidates are shown to be safe and effective, they will probably be deployed before full approval through emergency use authorisations or other strategies. With current knowledge, even in the absence of COVID-19 vaccines or treatments and comprehensive knowledge of the immune response to SARS-CoV-2, countries can navigate pathways to reduced transmission, decreased severe illness and mortality, and less economic disruption in the short and longer term.
    keywords: cov-2; covid-19; health; sars; transmission
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        item: #2563 of 7819
          id: cord-283208-uetq1p1n
      author: Castellano, Giuseppe
       title: Treatment of COVID-19 atypical pneumonia by early Tocilizumab administration in “non-critically-ill” patients on hemodialysis
        date: 2020-09-30
       words: 1371
      flesch: 32
     summary: Dialysis patients are characterized by an increased risk of cardiovascular, neoplastic, and infectious diseases, and are therefore more vulnerable to COVID-19. Given the extreme frailty of dialysis patients and considering the progressive deterioration of the clinical and laboratory parameters of our patients, we opted for early Tocilizumab administration [3] in an effort to avoid a sudden, precipitous deterioration in respiratory function that would have required immediate endotracheal intubation and mechanical ventilation.
    keywords: covid-19; patients; pneumonia; tocilizumab
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        item: #2564 of 7819
          id: cord-283215-dgysimh5
      author: Al-Jabir, Ahmed
       title: Impact of the coronavirus (COVID-19) pandemic on surgical practice - Part 2 (surgical prioritisation)
        date: 2020-05-12
       words: 9062
      flesch: 40
     summary: An anaesthetic guideline for COVID-19 positive patients is required. For more at risk patients (such as the elderly or immunosuppressed) with a low tumour burden, a reduced dose (≥85% of the standard dose) is recommended.
    keywords: cancer; care; cases; coronavirus; covid-19; emergency; guidelines; hospital; management; pandemic; patients; procedures; risk; surgeons; surgery; transplant; treatment; triage
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        item: #2565 of 7819
          id: cord-283221-y9m4n0de
      author: Ohara, Nobuyuki
       title: Stroke Systems of Care during the COVID-19 Epidemic in Kobe City
        date: 2020-09-30
       words: 2514
      flesch: 45
     summary: The number of hospitalized stroke patients and treatment types administered at 13 primary stroke Protected Code Stroke: JSS-PCS Impact of the COVID-19 epidemic on stroke care and potential solutions A rapid decrease in stroke, acute coronary syndrome, and corresponding interventions at 65 United States hospitals following emergence of COVID-19 Collateral effect of Covid-19 on stroke evaluation in the United States Decrease in hospital admissions for transient ischemic attack, mild, and moderate stroke during the COVID-19 Era Neurologic manifestations of hospitalized patients with coronavirus disease Large-vessel stroke as a presenting feature of Covid-19 in the young SARS2-CoV-2 and stroke in a New York healthcare system Early lessons from world war COVID, reinventing our stroke systems of care The authors wish to acknowledge Dr Chisato Miyakoshi for statistical assistance during this study. The Kobe Stroke Network surveyed the number of stroke patients admitted to all primary stroke centers (PSCs) in the city between March 1 and May 23, 2020, and between March 3 and May 25, 2019.
    keywords: care; city; covid-19; number; patients; stroke
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        item: #2566 of 7819
          id: cord-283236-vko7qdqp
      author: Paliwal, Prakash R.
       title: Impact of the COVID-19 pandemic on hyperacute stroke treatment: experience from a comprehensive stroke centre in Singapore
        date: 2020-07-13
       words: 3681
      flesch: 46
     summary: During DORSCON Orange, 13.9% (n = 20/144) of stroke activation patients were deemed as COVID-19 suspects upon ED screening, and 10 of them received acute recanalization therapy. Coronavirus disease (Covid-2019) situation reports Rapid progression to acute respiratory distress syndrome: review of current understanding of critical illness from covid-19 infection Who declares covid-19 a pandemic Risk assessment raised to dorscon orange What do the different dorscon levels mean Timing of recanalization after intravenous thrombolysis and functional outcomes after acute ischemic stroke Improvement in door-to-needle time in patients with acute ischemic stroke via a simple stroke activation protocol Protected code stroke: hyperacute stroke management during the coronavirus disease 2019 (Covid-19) pandemic Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a guideline for healthcare professionals from the american heart association/American Stroke Association Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct Infection prevention and control during health care when novel coronavirus (ncov) infection is suspected interim guidance Covid-19: are acute stroke patients avoiding emergency care?
    keywords: acute; covid-19; door; dorscon; orange; pandemic; patients; stroke; time
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        item: #2567 of 7819
          id: cord-283240-w4vxkbfv
      author: Silva, Ricardo Teixeira e
       title: Management of patients with spinal cord injury during the coronavirus disease pandemic
        date: 2020-07-15
       words: 1523
      flesch: 38
     summary: Spinal Cord Ser Cases Bascis guidance on management of spinal cord injury patients during coronavirus (covid-19) pandemic COVID-19 Guidance for People Living with Spinal Cord Injury Attention: Wheelchair and assistive technology users precautions for COVID-19 Medical care for spinal diseases during the COVID-19 pandemic The COVID-19 response must be disability inclusive Who should measure quality of life? key: cord-283240-w4vxkbfv authors: Silva, Ricardo Teixeira e; Cristante, Alexandre Fogaça; Marcon, Raphael Martus; de Barros-Filho, Tarcísio Eloy Pessoa title: Management of patients with spinal cord injury during the coronavirus disease pandemic date: 2020-07-15 journal: Clinics (Sao Paulo) DOI: 10.6061/clinics/2020/e2094 sha: doc_id: 283240
    keywords: cord; covid-19; patients; sci; spinal
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        item: #2568 of 7819
          id: cord-283246-dj7teo89
      author: Otsuka, Ryo
       title: Macrophage activation syndrome and COVID-19
        date: 2020-08-06
       words: 3233
      flesch: 34
     summary: Thus, serum levels of these cytokines are often at a high level in MAS patients [5] . In this context, cytokines highly produced in MAS patients are potential candidates, and some clinical reports provided promising results by cytokine-targeting therapy.
    keywords: activation; covid-19; il-6; macrophage; mas; patients; syndrome; tnf; treatment
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        item: #2569 of 7819
          id: cord-283248-tdp9x821
      author: Agarwal, Minu
       title: Impact of the COVID-19 pandemic on emergency CT head utilization in Ontario—an observational study of tertiary academic hospitals
        date: 2020-10-06
       words: 2920
      flesch: 48
     summary: The percentage of CT head studies revealing acute findings increased from 11% pre-COVID-19 to 23% during COVID-19 (p = 0.01*, Table 3 ). The percentage of CT head studies revealing nonacute findings decreased from 89% pre-COVID-19 to 78% during COVID-19, although showed no statistical significance, p = 0.93 (Table 3 , Fig. 3 ).
    keywords: acute; covid-19; emergency; head; pandemic; pre; study
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        item: #2570 of 7819
          id: cord-283259-cmim32lx
      author: Thombs, Brett D.
       title: Curating evidence on mental health during COVID-19: A living systematic review
        date: 2020-04-27
       words: 2053
      flesch: 35
     summary: A February 2020 review [2] identified 24 studies from previous infectious disease outbreaks on psychological outcomes among people quarantined after being exposed to others who had been infected, including studies from severe acute respiratory syndrome in mainland There are important limitations, however, that reduce our ability to easily apply that evidence to decision-making in COVID-19; among them, (1) few studies used validated mental health outcome measures; (2) no studies compared outcomes during quarantine to pre-outbreak mental health data, which reduces the ability to draw conclusions about changes in mental health and associated factors; (3) and no trials tested interventions to improve mental health symptoms during or following infectious disease outbreaks. [7] to evaluate (1) levels of mental health symptoms, prioritizing studies that assess changes in symptoms from pre-COVID-19 or compare concurrent samples between participants with different experiences with COVID-19 (e.g., those infected versus healthy comparison sample); (2) factors associated with levels or changes in symptoms during COVID-19, and (3) the effect of interventions on mental health symptoms during COVID-19.
    keywords: covid-19; evidence; health; review; studies; symptoms
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        item: #2571 of 7819
          id: cord-283260-9uo0hsst
      author: Sepúlveda-Vildósola, Ana Carolina
       title: Scientific Publications During the COVID-19 Pandemic
        date: 2020-05-25
       words: 1869
      flesch: 38
     summary: Research has adapted to this crisis by speeding up editorial processes for COVID-19 manuscripts. Clinical research and Evidence based medicine have been the tools by which physicians and public health policymakers take informed decisions.
    keywords: covid-19; disease; health; information; research
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        item: #2572 of 7819
          id: cord-283267-72wrzw09
      author: Moores, Lisa K.
       title: Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST Guideline and Expert Panel Report
        date: 2020-06-02
       words: 8243
      flesch: 35
     summary: An updated analysis High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Incidence of venous thromboembolism in hospitalized patients with COVID-19 Pulmonary Embolism in COVID-19 Patients: Awareness of an Increased Prevalence COVID-19-Related Severe Hypercoagulability in Patients Admitted to Intensive Care Unit for Acute Respiratory Failure Thrombotic complications of patients admitted to intensive care with COVID-19 at a teaching hospital in the United Kingdom Risk assessment of venous thromboembolism and bleeding in COVID-19 patients Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: The incidence of VTE in COVID-19 patients is not well defined, but early reports suggest it may be higher than in non-COVID hospitalized patients with similar degrees of illness, even in the presence of prophylactic anticoagulation.
    keywords: anticoagulant; anticoagulation; bleeding; covid-19; evidence; lmwh; medical; patients; risk; studies; thromboembolism; thromboprophylaxis; vte
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        item: #2573 of 7819
          id: cord-283287-073r80s7
      author: Farhoudian, Ali
       title: COVID-19 and Substance Use Disorders: Recommendations to a Comprehensive Healthcare Response. An International Society of Addiction Medicine Practice and Policy Interest Group Position Paper
        date: 2020-04-12
       words: 8137
      flesch: 34
     summary: Additionally PWUDs live in crowded locations and so screening and early identification of COVID-19 patients are important to break the cycle of transmission. The Lancet Chronic cocaine abuse and dilated cardiomyopathy Prize-based contingency management for the treatment of substance abusers: A meta-analysis Voluntary versus prescribed termination of methadone maintenance Opioid substitution treatment planning in a disaster context: Perspectives from emergency management and health professionals in Aotearoa/New Zealand Forensic medicine and toxicology: Drug addiction Management of the opiate abstinence syndrome Opioid substitution treatment planning in a disaster context: Perspectives from emergency management and health professionals in Aotearoa/New Zealand Efavirenz treatment and falsepositive results in benzodiazepine screening tests Understanding links among opioid use, overdose, and suicide At least 44 dead from drinking toxic alcohol in Iran after coronavirus cure rumor Community engagement-the harms of drug prohibition: Ongoing resistance in Vancouver's Downtown Eastside Prevalence and risk factors for unrecognized obstructive lung disease among urban drug users Relapse and relapse prevention Determinants of influenza vaccination in hard-to-reach urban populations A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-March Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study Kidney impairment is associated with in-hospital death of COVID-19 patients.
    keywords: addiction; buprenorphine; care; coronavirus; covid-19; drug; et al; health; infection; management; methadone; opioid; patients; people; pwud; risk; services; stress; transmission; treatment; use
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        item: #2574 of 7819
          id: cord-283308-z0j8ixwk
      author: Vardanjani, Hossein Molavi
       title: A cross-sectional study of Persian medicine and the COVID-19 pandemic in Iran: Rumors and recommendations
        date: 2020-07-23
       words: 2476
      flesch: 38
     summary: Rumors were defined as any false belief without supporting evidence in one of the PM practices, while PM recommendations were evidence-based comments approved by a PM specialist board council. The logistic regression model was also employed for multivariable analysis to determine the independent association of sociodemographics and other potential correlates with disagreements about PM rumors or recommendations.
    keywords: covid-19; health; pandemic; recommendations; rumors; study
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        item: #2575 of 7819
          id: cord-283310-5wam14aa
      author: Bevova, M. R.
       title: The New Coronavirus COVID-19 Infection
        date: 2020-09-09
       words: 4819
      flesch: 48
     summary: Situation Report -83, World Health Organization Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia Estimates of the reproduction number for seasonal, pandemic, and zoonotic influenza: A systematic review of the literature Transmission of COVID-19 in the terminal stage of incubation period: A familial cluster Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2) Transmission of 2019-nCoV infection from an asymptomatic contact in Germany Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1 Genomic characterization and epidemiology of 2019 novel coronavirus: Implications for virus origins and receptor binding Probable pangolin origin of SARS-CoV-2 associated with the COVID-19 outbreak The proximal origin of SARS-CoV-2 Epidemiology, genetic recombination, and pathogenesis of coronaviruses International Committee on Taxonomy of Viruses (ICTV Coronaviruses post-SARS: Update on replication and pathogenesis Identification of a novel coronavirus in patients with severe acute respiratory syndrome Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Labs rush to study coronavirus in transgenic animals: Some are in short supply Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2 Clinical characteristics of coronavirus disease 2019 in China Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72314 cases from the Chinese center for disease control and prevention Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy World Health Organization Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: A retrospective, single-center, descriptive study Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Novel coronavirus infection in hospitalized infants under 1 year of age in China Clinical features of patients infected with 2019 novel coronavirus in Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures COVID-19 infection: The perspectives on immune responses Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR A pneumonia outbreak associated with a new coronavirus of probable bat origin Specific Primers and Probes for Detection 2019 Novel Coronavirus, Chinese National Institute for Viral Disease Control and Prevention Fast, portable tests come online to curb coronavirus pandemic Coronavirus tests: Researchers chase new diagnostics to fight the pandemic Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV):
    keywords: cases; clinical; coronavirus; cov-2; covid-19; disease; infection; number; patients; sars; virus
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        item: #2576 of 7819
          id: cord-283340-ksyd5l56
      author: Choi, Geun Joo
       title: The Potential Role of Dyslipidemia in COVID-19 Severity: an Umbrella Review of Systematic Reviews
        date: 2020-09-21
       words: 4955
      flesch: 36
     summary: A meta-analysis Association of hypertension with the severity and fatality of SARS-CoV-2 infection: a meta-analysis Declined serum high density lipoprotein cholesterol is associated with the severity of COVID-19 infection Low high-density lipoprotein level is correlated with the severity of COVID-19 patients: an observational study Summarizing systematic reviews: methodological development, conduct and reporting of an umbrella review approach Cochrane Handbook for Systematic Reviews of Interventions: Cochrane Book Series Methodology in conducting a systematic review of systematic reviews of healthcare interventions Using existing systematic reviews in complex systematic reviews AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both Reaching for the stars -rating the quality of systematic reviews with the Assessment of Multiple Systematic Reviews (AMSTAR) 2 AMSTAR is a reliable and valid measurement tool to assess the methodological quality of systematic reviews GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables Impact of COVID-19 on neurological manifestations: an overview of stroke presentation in pandemic Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia -A systematic review, meta-analysis, and meta-regression Meta-analysis investigating the relationship between clinical features, outcomes, and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia In conclusion, we conducted an umbrella review to identify the findings and contents of systematic reviews and/or meta-analyses of the relationship between dyslipidemia and COVID-19 infection severity.
    keywords: covid-19; dyslipidemia; meta; quality; review; severity; studies; study
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        item: #2577 of 7819
          id: cord-283352-0l1ggmhx
      author: Javelot, H
       title: Panic and pandemic: narrative review of the literature on the links and risks of panic disorder as a consequence of the SARS-CoV-2 pandemic
        date: 2020-08-10
       words: 4442
      flesch: 27
     summary: Preliminary validation of Ley's model Panic disorder and the respiratory system: clinical subtype and challenge tests Respiratory manifestations of panic disorder: causes, consequences and therapeutic implications Panic disorder respiratory subtype: psychopathology, laboratory challenge tests, and response to treatment Laboratory, clinical and therapeutic features of respiratory panic disorder subtype The Deakin/Graeff hypothesis: focus on serotonergic inhibition of panic Panic disorder following torture by suffocation is associated with predominantly respiratory symptoms Association of panic disorder with a history of traumatic suffocation Major affective disorders in chronic obstructive pulmonary disease compared with other chronic respiratory diseases The role of panic-fear in comorbid asthma and panic disorder Hyperventilation in panic disorder and asthma: empirical evidence and clinical strategies Prospective impact of panic disorder and panicanxiety on asthma control, health service use, and quality of life in adult patients with asthma over a 4-year follow-up Psychiatric co-morbidity and asthma: These patients should be closely monitored, as these anxiety symptoms may transform into panic respiratory disorders.
    keywords: anxiety; asthma; covid-19; disorder; pandemic; panic; panic disorder; patients; risk
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        item: #2578 of 7819
          id: cord-283366-xwxg9991
      author: He, Tian
       title: Potential mechanisms of Chinese Herbal Medicine that implicated in the treatment of COVID-19 related renal injury
        date: 2020-08-10
       words: 4981
      flesch: 30
     summary: Renal injury targets were mapped to those of COVID-19 using Venny plotting software (V2.1) to obtain potential targets of renal injury after COVID-19 infection. In this study, we searched prescriptions in the treatment of renal injury extensively and the potential mechanisms to treat COVID-19 related renal injury were investigated.
    keywords: chm; core; covid-19; herbs; infection; ingredients; injury; kidney; pathway; patients; targets; treatment
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        item: #2579 of 7819
          id: cord-283367-azzy2t1a
      author: Rahman, Asma
       title: Neurological manifestations in COVID-19: A narrative review
        date: 2020-09-10
       words: 4452
      flesch: 48
     summary: 14 Awareness by clinicians of the possibility of CVD in COVID-19 patients may lead to more timely management decisions and thus a reduction in both morbidity and mortality. Reports an association between stroke and pneumonia severity in COVID-19 patients.
    keywords: acute; cov-2; covid-19; csf; manifestations; patients; sars; stroke
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        item: #2580 of 7819
          id: cord-283368-j2vjylum
      author: Erika, Poggiali
       title: Triage decision-making at the time of COVID-19 infection: the Piacenza strategy
        date: 2020-05-09
       words: 1338
      flesch: 44
     summary: At the beginning of the Italian COVID-19 outbreak, we based the suspicion of COVID-19 infection upon the epidemiological risk: the exposure to confirmed COVID-19 case or prolonged contact with people in the geographical area with confirmed COVID-19 cases in the past 14 days. As consequence, our own hospital became a quite totally dedicated COVID-19 hospital with 80% of beds reserved for ill COVID-19 patients.
    keywords: covid-19; emergency; lung; patients
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        item: #2581 of 7819
          id: cord-283372-c20i99qa
      author: Sanchis-Gomar, Fabian
       title: Amiodarone in the COVID-19 Era: Treatment for Symptomatic Patients Only, or Drug to Prevent Infection?
        date: 2020-08-01
       words: 2615
      flesch: 32
     summary: We present here the rationale for amiodarone use in the COVID-19 scenario, as well as whether or not amiodarone administration represents a potential strategy to prevent SARS-CoV-2 infection, rather than simply used to treat patients already symptomatic and/or with severe COVID-19, based on current evidence. Amiodarone has been associated with hepatic transaminitis, thyroid dysfunction, and pulmonary toxicity, although these adverse effects are directly related to the duration of treatment (amiodarone toxicity is cumulative and dose-dependent)
    keywords: amiodarone; covid-19; effects; infection; patients; sars; use
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        item: #2582 of 7819
          id: cord-283376-6wolrfvk
      author: Yin, M.
       title: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection During Pregnancy In China: A Retrospective Cohort Study
        date: 2020-04-11
       words: 4117
      flesch: 51
     summary: Fever was the most common symptom in both groups, but pregnant patients had a significantly lower proportion of fever than non-pregnant patients (54·8% vs. 87·5%, p=0·006). Moreover, pregnant patients had a shorter average interval from onset to hospitalization than non-pregnant patients (7·80 ±7·0d vs. 13·2 ± 8·2d, p=0·005), while a higher proportion of pregnant patients was diagnosed as severe or critical COVID-19 than non-pregnant patients (32·3% vs. 11·4%, p=0·039).
    keywords: coronavirus; cov-2; covid-19; patients; preprint; sars; women
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        item: #2583 of 7819
          id: cord-283380-l60yyr6l
      author: Grabbe, Stephan
       title: Systemic immunosuppression in times of COVID‐19: Do we need to rethink our standards?
        date: 2020-08-02
       words: 2579
      flesch: 25
     summary: Although this is the normal case also in COVID-19 patients, in individual patients the virus can cause hyperactivation of the immune system, which then triggers the clinical picture of acute respiratory distress syndrome (ARDS). A report on Covid-19 disease in 86 patients with a range of autoimmune diseases of the skin, joints and intestines treated with various immunosuppressive drugs showed a hospitalization rate comparable to that of COVID-19 patients in the general population [24] .
    keywords: course; covid-19; disease; patients; sars; therapy
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        item: #2584 of 7819
          id: cord-283409-ynwgdz52
      author: Baggett, Travis P.
       title: Clinical Outcomes, Costs, and Cost-effectiveness of Strategies for People Experiencing Sheltered Homelessness During the COVID-19 Pandemic
        date: 2020-10-20
       words: 1742
      flesch: 37
     summary: After acquiring SARS-CoV-2 infection, individuals may progress through the following health states (eFigure 1): • Pre-infectious latency • Asymptomatic infection • Mild/moderate illness: symptomatic • Severe illness: dyspnea and/or hypoxemia ideally managed in a hospital with standard supplemental oxygen but not requiring intensive care unit (ICU) • Critical illness: ideally managed in an ICU with high-flow supplemental oxygen, non-invasive positive pressure ventilation, or invasive mechanical ventilation • Recuperation: for those recuperating from critical illness and improving while remaining in the hospital or other health care facility • Recovered Individuals in the asymptomatic infection, mild/moderate illness, and severe illness states can transition directly to the recovered state. This nominal transmission rate captures the ratio of daily infectivity stratified by illness states.
    keywords: illness; individuals; infection; pcr
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        item: #2585 of 7819
          id: cord-283439-hqdq2qrh
      author: Rahman, Mohammad Tariqur
       title: Can Zn Be a Critical Element in COVID-19 Treatment?
        date: 2020-05-26
       words: 5258
      flesch: 44
     summary: Zinc is widely distributed in human tissues, where virtually all Zn is present in intracellular compartments such as the nucleus (30-40%), cytosol, and other organelles and specialized vesicles (50%), and the rest is bound with cell membrane proteins On March 11, 2020 , the World Health Organization (WHO) declared Coronavirus Disease 2019 (COVID-19) outbreak as pandemic caused by another member of the Coronaviridae family-SARS-CoV-2. SARS-CoV-2 primarily infects cells of the small air sacs known as alveoli consisting of alveolar cells and alveolar macrophages.
    keywords: cells; chloroquine; coronavirus; cov-2; covid-19; hydroxychloroquine; infection; patients; proteins; replication; rna; sars; treatment; zinc
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        item: #2586 of 7819
          id: cord-283440-8du0s33p
      author: Ciuca, Ioana M
       title: COVID-19 in Children: An Ample Review
        date: 2020-06-25
       words: 5646
      flesch: 38
     summary: A total of 147 published papers were found on SARS-CoV-2 in general populations, 48 full-text articles that involved children were published between January 1, 2020 and April, 1 2020 and 44 considered relevant were reviewed for this study. To be used for screening, chest CT scans should detect lung changes in asymptomatic children as well as in symptomatic cases, but the median sensitivity of CT of 60% in pediatric patients with confirmed COVID-19 is not sufficient to expose asymptomatic children to harmful radiation.
    keywords: adults; cases; children; coronavirus; cov-2; covid-19; disease; infection; lung; sars; study
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        item: #2587 of 7819
          id: cord-283458-ndzafv3c
      author: Hall, MAJ Andrew
       title: Converting a Small Surgical Team into a Pandemic Response Team for an Isolated Population
        date: 2020-04-10
       words: 2161
      flesch: 43
     summary: The military trains and equips medical teams to provide care for these troops in austere locations. If medical treatment team members are infected, QuaranƟned Isolated they should remain on duty as long as physically able, but will be restricted to the isolated population.
    keywords: covid-19; disease; personnel; population; quarantine; team
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        item: #2588 of 7819
          id: cord-283461-xcyvisqu
      author: Berthelot, Jean-Marie
       title: Kawasaki-like diseases and thrombotic coagulopathy in COVID-19: delayed over-activation of the STING pathway?
        date: 2020-07-05
       words: 5391
      flesch: 35
     summary: The hypothesis of a central role of STING activation in COVID-19 has been reinforced by: 1-the observation that STING is mostly expressed by endothelial cells and pneumocytes type II Since STING also activate coagulation through another independent pathway (STING-ITPR1-calcium release-gasdermin D-pyroptosis) which can lead to TF deposition in various tissues, low-dose aspirin or dipyridamole could be added to other STING inhibitors to better prevent the thrombotic coagulopathy of COVID-19 patients in patients with biological signs of coagulation dysfunction.
    keywords: activation; aspirin; cells; covid-19; disease; dna; pathway; patients; sars; sting
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        item: #2589 of 7819
          id: cord-283464-v4x0gaqc
      author: Yu, Kimberley
       title: Otorhinolaryngology, head and surgery practice during the COVID-19 pandemic
        date: 2020-06-06
       words: 498
      flesch: 50
     summary: key: cord-283464-v4x0gaqc authors: Yu, Kimberley; Wei, Jun-Min; Li, Da-Qing; Fang, Yuxin title: Otorhinolaryngology, head and surgery practice during the COVID-19 pandemic date: 2020-06-06 journal: World J Otorhinolaryngol Head Neck Surg DOI: 10.1016/j.wjorl.2020.06.001 sha: doc_id: 283464 cord_uid: v4x0gaqc nan Otorhinolaryngology, head and surgery practice during the COVID-19 pandemic
    keywords: covid-19; otorhinolaryngology
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        item: #2590 of 7819
          id: cord-283477-6clp5nz7
      author: Gabrielson, Andrew T.
       title: Proposed Changes to the 2021 Residency Application Process in the Wake of COVID-19
        date: 2020-06-01
       words: 3117
      flesch: 30
     summary: Second, we recommend a formal restriction on the number of visiting rotations medical students are expected to complete, an approach already supported by program directors. This crisis is not the first time that medical students applying to residency have been unable to complete core and elective rotations at their home institutions because of a disaster scenario.
    keywords: covid-19; medical; programs; residency; rotations; students
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        item: #2591 of 7819
          id: cord-283485-xit6najq
      author: Van Damme, Wim
       title: The COVID-19 pandemic: diverse contexts; different epidemics—how and why?
        date: 2020-07-27
       words: 9634
      flesch: 46
     summary: Cluster of coronavirus disease 2019 (Covid-19) in the French Alps Investigation of a COVID-19 outbreak in Germany resulting from a single travelassociated primary case: a case series A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating personto-person transmission: a study of a family cluster High SARS-CoV-2 attack rate following exposure at a Choir practice Estimating the overdispersion in COVID-19 transmission using outbreak sizes outside China Why do some COVID-19 patients infect many others, whereas most don't spread the virus at all? What we already know The available information on SARS-CoV-2 and the spectrum of COVID-19 disease is summarised in tables 6 and 7.
    keywords: coronavirus; countries; cov-2; covid-19; disease; epidemic; health; human; immunity; influenza; measles; pandemic; sars; spread; transmission; virus
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        item: #2592 of 7819
          id: cord-283500-mp2f102i
      author: Mathiesen, T.
       title: A snapshot of European neurosurgery December 2019 vs. March 2020: just before and during the Covid-19 pandemic
        date: 2020-07-08
       words: 7152
      flesch: 44
     summary: Neurosurgical centers responded swiftly and effectively to a sudden decrease of neurosurgical capacity due to relocation of resources to pandemic care. Neurosurgery is influenced by the redistribution of medical resources to those acutely needing Covid-19 care and by the need to handle or prevent Covid-19 among neurosurgical patients and staff
    keywords: beds; care; centers; covid-19; december; march; neurosurgical; pandemic; patients; resources; surgery
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        item: #2593 of 7819
          id: cord-283513-3f4rsgzm
      author: Jaywant, Abhishek
       title: Behavioral interventions in acute COVID-19 recovery: A new opportunity for integrated care
        date: 2020-07-07
       words: 1265
      flesch: 29
     summary: There are likely multifactorial physiologic and psychologic contributions to anxiety symptoms as neurologically-based sensory changes (e.g., dysautonomia) occur in deconditioned COVID-19 patients [3] . Patients are medically monitored and work towards rehabilitation goals with daily physical and occupational therapy (PT/OT).
    keywords: covid-19; patients
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        item: #2594 of 7819
          id: cord-283521-smg1uw35
      author: García-Hernández, Rafael
       title: Inmunomodulación mediante CONVEHY® para COVID-19: de la tormenta al anticiclón de citoquinas
        date: 2020-08-29
       words: 1653
      flesch: 33
     summary: Recientemente se publicaron los resultados preliminares del uso del protocolo CONVEHY, donde se puede encontrar una comparación de los resultados antes y después de la inclusión del citrato (9) . La razón de la letalidad de COVID-19 es una sepsis viral.
    keywords: con; covid-19; del; las; los; pacientes; para; por; puede; que; una
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        item: #2595 of 7819
          id: cord-283612-tzaa82kb
      author: Hedima, Erick Wesley
       title: Community Pharmacists: On the frontline of health service against COVID-19 in LMICs
        date: 2020-04-17
       words: 2157
      flesch: 43
     summary: key: cord-283612-tzaa82kb authors: Hedima, Erick Wesley; Adeyemi, Michael Samuel; Ikunaiye, Nasiru Yakubu title: Community Pharmacists: On the frontline of health service against COVID-19 in LMICs date: 2020-04-17 journal: Res Social Adm Pharm DOI: 10.1016/j.sapharm.2020.04.013 sha: doc_id: 283612 cord_uid: tzaa82kb The COVID-19 outbreak is a global public health crisis which has affected healthcare practice across professions. Community pharmacists are the most accessible healthcare professionals to the general public and have a lot to offer amid the COVID-19 response.
    keywords: community; covid-19; drug; health; patients; pharmacists; public
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        item: #2596 of 7819
          id: cord-283616-ef84i589
      author: Ye, Zheng
       title: Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review
        date: 2020-03-19
       words: 2927
      flesch: 41
     summary: Emerging atypical CT manifestations, including airway changes, pleural changes, fibrosis, nodules, etc., were demonstrated in COVID-19 patients. In COVID-19 diagnosis, real-time reverse transcription polymerase chain reaction (RT-PCR) of viral nucleic acid is regarded as the reference standard; however, recent studies addressed the importance of chest computed tomography (CT) examination in COVID-19 patients with false negative RT-PCR results [4, 5] , and reported the CT sensitivity as 98% [6] .
    keywords: 2019; coronavirus; covid-19; disease; patients; sign
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        item: #2597 of 7819
          id: cord-283623-umqu07te
      author: Ponce-Alonso, Manuel
       title: Impact of the coronavirus disease 2019 (COVID-19) pandemic on nosocomial Clostridioides difficile infection
        date: 2020-09-08
       words: 3230
      flesch: 34
     summary: We compared the incidence density (cases per 10,000 patient days) of nosocomial CDI in a tertiary-care teaching hospital in Madrid over 2 periods: (1) the peak incidence of COVID-19 at our hospital (COVID-19 period: March 11, 2020, to May 11, 2020) and (2) the same period of the previous year (control period: March 11, 2019, to May 11, 2019) . Evolution of C. difficile infection (CDI) over time, from control period (left) to COVID-19 period (right).
    keywords: cdi; control; covid-19; days; difficile; patient; period
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        item: #2598 of 7819
          id: cord-283663-odrkfguc
      author: Dobson, Dre'Von A.
       title: COVID‐19 pandemic perspectives: A scientific silver lining?
        date: 2020-09-28
       words: 1450
      flesch: 44
     summary: key: cord-283663-odrkfguc authors: Dobson, Dre'Von A.; Wolberg, Alisa S. title: COVID‐19 pandemic perspectives: A scientific silver lining? date: 2020-09-28 journal: That is a shame, since the data on this subject are clear; more diversity in science means more perspectives are considered and more problems solved.
    keywords: covid-19; diversity; pandemic; science; scientists
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        item: #2599 of 7819
          id: cord-283673-oyefmgl3
      author: Garcia, Marc A
       title: The Color of COVID-19: Structural Racism and the Pandemic’s Disproportionate Impact on Older Racial and Ethnic Minorities
        date: 2020-08-05
       words: 3861
      flesch: 35
     summary: Questions regarding which segments of U.S. society are at an elevated risk for severe illness and death from the coronavirus-and how and why-are central to understanding and addressing disparities in COVID-19 health outcomes. In order to understand racial/ethnic disparities in COVID-19 health outcomes among older adults, it is important to consider how social and historical contexts contribute to different levels of risks over time.
    keywords: adults; blacks; care; covid-19; health; latinxs; racism; risk
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        item: #2600 of 7819
          id: cord-283696-3a0s64sm
      author: Haen, Pierre
       title: CORONA-steps for tracheotomy in COVID-19 patients: A staff-safe method for airway management
        date: 2020-04-20
       words: 646
      flesch: 44
     summary: Meta-Analysis Comparison of Open Versus Percutaneous Tracheostomy: The Laryngoscope Infection control measures for operative procedures in severe acute respiratory syndrome-related patients Safe tracheostomy for patients with severe acute respiratory syndrome Safety Recommendations for Evaluation and Surgery of the Head and Neck During the COVID-19 Pandemic Surgical Considerations for Tracheostomy During the COVID-19 Pandemic: Lessons Learned From the Severe Acute Respiratory Syndrome Outbreak Improving staff safety during tracheostomy in COVID-19 patients Even if tracheostomy procedures can be used in COVID-19 patient management, no evidence-based recommendations for the protection of healthcare workers performing tracheostomies for these patients exist to date.
    keywords: covid-19; patients
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        item: #2601 of 7819
          id: cord-283719-zmizyx7e
      author: Cheng, Yuan-Yang
       title: Rehabilitation Programs for Patients with COronaVIrus Disease 2019: Consensus Statements of Taiwan Academy of Cardiovascular and Pulmonary Rehabilitation
        date: 2020-08-17
       words: 2816
      flesch: 23
     summary: 36 Rehabilitation interventions for such patients should include the following: (1) Active or active-assisted range of motion (ROM) exercise: Patients with moderate to severe disease who are able to actively move their extremities are encouraged to engage in active or active-assisted ROM exercises to maintain or improve joint integrity and prevent joint contracture and soft-tissue shortening. However, a formal exercise test should still be considered in patients with advanced CVD with proper clinical disinfection following CDC 11 (3) Pulmonary disease: Patients with previous chronic pulmonary diseases could develop much more airway secretions than those without.
    keywords: covid-19; disease; exercise; patients; rehabilitation; risk; training
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        item: #2602 of 7819
          id: cord-283729-ekrcop2p
      author: Allam, Hassan H
       title: Pericardial Fluid in a COVID-19 Patient: Is It Exudate or Transudate?
        date: 2020-05-12
       words: 681
      flesch: 49
     summary: In view of the patient's symptoms and the echo findings, pericardial aspiration was performed aseptically with appropriate PPE, and 550 ml of pericardial fluid was drained. In conclusion, to the best of our knowledge, we have described the first analysis of pericardial fluid in a COVID-19 patient with a large pericardial effusion.
    keywords: covid-19; fluid
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        item: #2603 of 7819
          id: cord-283730-rshlenku
      author: Sah, Ranjit
       title: Impact of COVID-19 on tourism in Nepal
        date: 2020-07-07
       words: 1375
      flesch: 55
     summary: Nepal's first case of COVID-19 and public health response COVID-19 Batters hopes of sound economic growth The world Bank In Nepal Nepal tourism generated Rs240b and supported 1m jobs last year: reportt Visit Nepal 2020 Tourist Arrivals: 2% Drop in January Nepali labor migrants, Covid-19, and the state Foreign aid, and development in Nepal Coronavirus in Nepal: laborers returning home allege bias in hospitals. key: cord-283730-rshlenku authors: Sah, Ranjit; Sigdel, Shailendra; Ozaki, Akihiko; Kotera, Yasuhiro; Bhandari, Divya; Regmi, Priyanka; Rabaan, Ali A; Mehta, Rachana; Adhikari, Mahesh; Roy, Namrata; Dhama, Kuldeep; Tanimoto, Tetsuya; Rodríguez-Morales, Alfonso J; Dhakal, Rachana title: Impact of COVID-19 on tourism in Nepal date: 2020-07-07 journal: J Travel Med DOI: 10.1093/jtm/taaa105 sha: doc_id: 283730 cord_uid: rshlenku nan *To whom correspondence should be addressed.
    keywords: covid-19; government; health; nepal
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        item: #2604 of 7819
          id: cord-283744-qkvo6cji
      author: Marston, Cicely
       title: Community participation is crucial in a pandemic
        date: 2020-05-04
       words: 1212
      flesch: 39
     summary: key: cord-283744-qkvo6cji authors: Marston, Cicely; Renedo, Alicia; Miles, Sam title: Community participation is crucial in a pandemic date: 2020-05-04 journal: Lancet DOI: 10.1016/s0140-6736(20)31054-0 sha: doc_id: 283744 cord_uid: qkvo6cji nan Community participation is essential in the collective response to coronavirus disease 2019 (COVID-19), from compliance with lockdown, to the steps that need to be taken as countries ease restrictions, to community support through volunteering. 2 Global health guidelines already emphasise the importance of community participation.
    keywords: community; covid-19; health; response
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        item: #2605 of 7819
          id: cord-283758-0z3jwwby
      author: Rokadiya, S.
       title: COVID-19: Outcomes of patients with confirmed COVID-19 re-admitted to hospital.
        date: 2020-07-08
       words: 973
      flesch: 45
     summary: Age, sex, comorbidities, ethnicity and deprivation have all been shown to correlate with worse outcomes in patients with COVID-19, however the outcomes of hospitalised patients once discharged remains unknown [3] [4] [5] . The median age of the re-admission group was higher at 73 years (IQR 58 -82) compared to discharged patients of (429/729) in all COVID-19 patients and ethnicity was predominantly of Black, Asian or Minority Ethnic (BAME) background in both groups (absolute 62.5% discharged vs 57.1% re-admission)
    keywords: admission; covid-19; patients
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        item: #2606 of 7819
          id: cord-283764-qw8qhmv1
      author: Bai, Hua
       title: Efficacy of human coronavirus immune convalescent plasma for the treatment of corona virus disease -19 disease in hospitalized children: A protocol for systematic review and meta analysis
        date: 2020-11-06
       words: 2123
      flesch: 47
     summary: [22] With the spread of COVID-19, for severe and critical cases, in addition to symptomatic treatment, respiratory support, and circulatory support, CP treatment is also an important treatment measure to save patients. This study will provide high-quality comprehensive evidence for the effectiveness and safety of human coronavirus immuno CP in the treatment of COVID-19 in children CONCLUSIONS: The results of this study will provide the basis for the effectiveness and safety of human coronavirus immuno CP treatment of COVID-19 in children.
    keywords: analysis; coronavirus; covid-19; data; treatment
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        item: #2607 of 7819
          id: cord-283769-n38f0i5z
      author: Georgiou, Neophytos
       title: COVID-19-related conspiracy beliefs and their relationship with perceived stress and pre-existing conspiracy beliefs
        date: 2020-06-16
       words: 5058
      flesch: 45
     summary: As anticipated, COVID-19 conspiracy beliefs were strongly related to the other measures of conspiracy belief. We also examined the relationship between COVID-19 conspiracy beliefs and attitudes towards the government response to the pandemic.
    keywords: beliefs; conspiracy; covid-19; events; study; theories
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        item: #2608 of 7819
          id: cord-283779-mudwcypl
      author: Lauretani, Fulvio
       title: Assessment and treatment of older individuals with COVID-19 multi-system disease: clinical and ethical implications
        date: 2020-05-11
       words: 9739
      flesch: 35
     summary: As a consequence of multimorbidity, polypharmacy defined as the number of drugs reported at hospital admission and the potential drug-drug interactions require a careful evaluation in older COVID-19 patients. These principles have been often ignored, especially in older COVID-19 patients.
    keywords: acute; care; coronavirus; covid-19; day; days; disease; infection; mortality; nutritional; patients; phase; pulmonary; risk; sars; symptoms; syndrome; treatment; use; virus
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        item: #2609 of 7819
          id: cord-283809-9sv5bax0
      author: Baldacchino, Alexander
       title: COVID-19 and Substance Use Disorder: Study Protocol for the International Society of Addiction Medicine Practice and Policy Interest Group Global Survey
        date: 2020-04-15
       words: 3235
      flesch: 44
     summary: The study participants consisted of nationally-representative informants from different countries who (a) are experts in the field of addiction medicine and health related services, and (b) active in the substance use treatment policy and/or service during the COVID-19 epidemic. More knowledge about the current situation can help us make better plans for this and future similar situations; So, we, as the International Society of Addiction Medicine Practice and Policy Interest Group, aimed to design a study in order to get in touch with experts of addiction medicine in different countries of the world and ask them to share with us what is going on in their countries and how substance users are affected.
    keywords: addiction; covid-19; medicine; pandemic; participants; people; substance; survey; use
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        item: #2610 of 7819
          id: cord-283843-qgpxauj1
      author: Endstrasser, Franz
       title: The negative impact of the COVID-19 lockdown on pain and physical function in patients with end-stage hip or knee osteoarthritis
        date: 2020-06-18
       words: 2495
      flesch: 49
     summary: Knee OA patients showed a faster deterioration in pain score compared to hip OA patients during lockdown, which suggests that loss of activity has a higher impact on OA knees. Additional results attained by the correlations between physical activity, pain, physical and mental function (Table 3) , the intra-and inter-group analysis for the hip and knee OA patients (Table 4) , and the intra-and inter-group analysis of patients who prefer surgery as soon as possible compared to those who want to wait (Table 5 ) are given in the corresponding tables, respectively.
    keywords: covid-19; hip; knee; lockdown; patients
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        item: #2611 of 7819
          id: cord-283850-kt8n6pg2
      author: Steardo, Luca
       title: Psychiatric face of COVID-19
        date: 2020-07-30
       words: 7892
      flesch: 19
     summary: An excessive glial reactivity due to persistent exposure to pro-inflammatory cytokines also contributes to synapse loss and neuronal death 63, 64 . Ageing substantially affects the levels and the activity of pro-inflammatory cytokines in the CNS.
    keywords: analysis; brain; coronavirus; cov-2; covid-19; disease; disorder; il-6; infection; inflammation; levels; patients; psychiatric; sars; stress; subjects
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        item: #2612 of 7819
          id: cord-283877-qy6s5xrw
      author: Vöö, Stefan
       title: Single photon emission computed tomography-computed tomography lung perfusion imaging during the COVID-19 pandemic: does nuclear medicine need to reconsider its guidelines?
        date: 2020-07-03
       words: 1754
      flesch: 30
     summary: COVID-19 and ventilation/perfusion (v/q) lung studies Uk/ guidance/high-consequence-infectious-diseases-hcid COVID-19 pandemic: guidance for nuclear medicine departments COVID19 -Nuclear Medicine Departments, be prepared Re: Ventilationperfusion scans during the coronavirus disease 2019 (covid-19) outbreak COVID-19 in the Nuclear Medicine Department, be prepared for ventilation scans as well Diagnostic evaluation of pulmonary embolism during the COVID-19 pandemic Ventilation/perfusion SPECT imaging-diagnosing other cardiopulmonary diseases beyond pulmonary embolism Detection of pulmonary embolism with combined ventilation-perfusion SPECT and low-dose CT: head-to-head comparison with multidetector CT angiography SPECT-CT/VQ versus CTPA for diagnosing pulmonary embolus and other lung pathology: Pre-existing lung disease should not be a contraindication Value of perfusion lung scan in the diagnosis of pulmonary embolism: results of the Prospective Investigative Study of Acute Pulmonary Embolism Diagnosis (PISA-PED) Perfusion lung scintigraphy for the diagnosis of pulmonary embolism: a reappraisal and review of the Prospective Investigative Study of Acute Pulmonary Embolism Diagnosis methods Sensitivity and specificity of perfusion scintigraphy combined with chest radiography for acute pulmonary embolism in PIOPED II Is there a role for lung perfusion However, ventilation SPECT scan, although debatable, may still be performed, if lung perfusion scan is abnormal, after PCR swab testing preferably in PCR Covid-19 negative patients and with use or full PPE for aerosol generating procedures.
    keywords: covid-19; medicine; perfusion; pulmonary; ventilation
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        item: #2613 of 7819
          id: cord-283900-4pa93xqi
      author: Khan, M. Ali
       title: Perceptions of Occupational Risk and Changes in Clinical Practice of U.S. Vitreoretinal Surgery Fellows during the COVID-19 Pandemic
        date: 2020-05-22
       words: 2492
      flesch: 41
     summary: Conclusion and Relevance: Suspected or confirmed clinical exposure to COVID-19 positive patients occurred in approximately one-fifth of trainee respondents. 328 329 Approximately one-fifth of U.S. vitreoretinal surgery fellows had suspected or confirmed clinical exposure to COVID-19 positive patients.
    keywords: covid-19; ophthalmology; ppe; reduction; respondents; risk
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        item: #2614 of 7819
          id: cord-283909-xwy3rm3f
      author: Lippi, Giuseppe
       title: Eosinophil count in severe coronavirus disease 2019 (COVID-19)
        date: 2020-04-21
       words: 571
      flesch: 42
     summary: The results of the pooled analysis is shown in figure 1 , attesting that the eosinophil count was not found to be significantly different between patients with or without severe COVID-19 (WMD, -0.01×10 9 ; 95% CI, -0.07 to 0.04×10 9; I2, 0%; Weighted mean difference (WMD) and 95% confidence interval (95% CI) of eosinophil count in patients with or without severe coronavirus disease 2019 (COVID-19). key: cord-283909-xwy3rm3f authors: Lippi, Giuseppe; Henry, Brandon M title: Eosinophil count in severe coronavirus disease 2019 (COVID-19) date: 2020-04-21 journal: QJM DOI: 10.1093/qjmed/hcaa137 sha: doc_id: 283909 cord_uid: xwy3rm3f nan We read with interest the article of Qian et al, 1 who showed a trend, though nonsignificant, towards eosinopenia in patients with coronavirus disease 2019 (COVID-19).
    keywords: covid-19; patients
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        item: #2615 of 7819
          id: cord-283912-ha2xwjzy
      author: Zheng, Meijuan
       title: Serum inflammatory factors are positively correlated with the production of specific antibodies in coronavirus disease 2019 patients
        date: 2020-09-22
       words: 1525
      flesch: 36
     summary: 12 More notably, convalescent plasma from recovered COVID-19 patients with high levels of anti-SARS-CoV-2 antibodies has been used for the treatment of COVID-19 patients, but this treatment has at least a theoretical possibility of being associated with ADE 13 and may therefore have the unintended consequence of enhancing the severity of COVID-19 infection. Collectively, these results indicated that severe COVID-19 illness induced strong humoral immune responses, which is consistent with previous studies showing higher IgG titers in severe patients than in nonsevere patients.
    keywords: covid-19; levels; patients; rbd
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        item: #2616 of 7819
          id: cord-283915-yqj9gzan
      author: Ahmad, Naveed
       title: Impact of Covid19 on a tertiary care pediatric oncology and stem cell transplant unit in Riyadh, Saudi Arabia
        date: 2020-07-12
       words: 679
      flesch: 37
     summary: Despite the concerns that chemotherapy-related immunosuppression is a risk factor to develop severe disease with Covid19, there is growing evidence that coronavirus-related mortality is extremely rare in pediatric cancer patients. In addition to the numbers and types of malignancies, we looked at the pattern of presentation, need for nonelective pediatric intensive care unit (PICU) stay at presentation, and morbidity or mortality within the first week after presentation.
    keywords: cancer; covid-19; presentation
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        item: #2617 of 7819
          id: cord-283918-h8awaxxw
      author: Maeker, Éric
       title: Annonce du diagnostic et accompagnement de fin de vie du COVID-19 en période de confinement au sein d’une unité gériatrique aiguë
        date: 2020-05-21
       words: 3607
      flesch: 57
     summary: Elle présente l'ensemble des liens utiles à la constitution des messages La réception du statut virologique, analysé à la lumière des résultats de la tomodensitométrie thoracique, défini si oui ou non l'infection est diagnostiquée.
    keywords: covid-19; dans; des; est; les; leur; par; personnes; pour; proches; soins; sont; une; équipes
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        item: #2618 of 7819
          id: cord-283927-683mzwga
      author: Jette, Alan M
       title: Responding to the Coronavirus Pandemic
        date: 2020-07-18
       words: 1126
      flesch: 26
     summary: Covid19.who.int Accessed COVID-19 and racial/ethnic disparities Italian physical therapists' response to the novel COVID-19 emergency Impact of COVID-19 on physical therapist practice in Portugal COVID-19 and the advancement of digital physical therapist practice and telehealth Home-and community-based physical therapist management of adults with post-intensive care syndrome The essential role of home-and community-based physical therapists during the COVID-19 pandemic In a second Point of View article, Dr Vanessa Alpalhão and Dr Miguel Alpalhão 4 discuss some of the adaptations being made in physical therapist practice in Portugal in an effort to respond to the COVID-19 crisis and the needs of their patients.
    keywords: care; covid-19; practice; therapist
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        item: #2619 of 7819
          id: cord-283948-rb9rrkxb
      author: Gavriilidis, Paschalis
       title: The Impact of COVID-19 Global Pandemic on Morbidity and Mortality of Liver Transplant Recipients Children and Adults: A Systematic Review of Case Series
        date: 2020-06-25
       words: 1597
      flesch: 43
     summary: The number of reported cases of liver transplant patients with COVID-19 is very few and the reported clinical manifestation and symptoms do not differ from those of the general population. So far there is no ample evidence to report any remarkable differences in the manifestation of disease in liver transplant patients compared to general population.
    keywords: covid-19; liver; sars; transplant
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        item: #2620 of 7819
          id: cord-283953-vuvd6mvz
      author: KM, S.
       title: Trace, Quarantine, Test, Isolate and Treat: A Kerala Model of Covid-19 Response
        date: 2020-06-19
       words: 4165
      flesch: 57
     summary: Finally, Kerala has 2.5 million migrant laborers from other states. One of the two major challenges that Kerala faced in this period was the security of the migrant workers from other states, just after the announcement of the national lockdown, the state set up nearly 20000 camps for migrant laborers, by calling them, 'guest workers'.
    keywords: cases; covid-19; kerala; lockdown; people; phase; preprint; state
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        item: #2621 of 7819
          id: cord-283956-zgrtux7i
      author: Amin, Sk. Abdul
       title: Fight against novel coronavirus: A perspective of medicinal chemists
        date: 2020-06-12
       words: 5115
      flesch: 47
     summary: SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection Endoribonuclease from SARS CoV-2. The crystal structure of papainlike protease of SARS CoV-2 6W9C Deposited It is a challenging task to identify effective anti-COVID-19 drugs urgently.
    keywords: anti; binding; coronavirus; cov-2; covid-19; discovery; drug; inhibitors; novel; protein; receptor; sars; screening; structure
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        item: #2622 of 7819
          id: cord-283969-wqrzaxsu
      author: Antonucci, Michele
       title: The impact of COVID-19 outbreak on urolithiasis emergency department admissions, hospitalizations and clinical management in central Italy: a multicentric analysis
        date: 2020-10-28
       words: 2928
      flesch: 36
     summary: Patients and methods We conducted a multicentric retrospective analysis of ED admissions in three high volume urology departments (one directly involved in COVID-19 patients management and two not involved) in Rome - Italy between March and April 2020 and in the same period of 2019. In Italy not all the regions were affected by the same overload of COVID-19 cases; some cities had the opportunity to select the hospitals in which infected patients had to be admitted, leaving some structures free from COVID-19 patients.
    keywords: admissions; covid-19; emergency; pandemic; patients; stone; urolithiasis
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        item: #2623 of 7819
          id: cord-284008-vlwdtjbe
      author: Li, Na
       title: The Application of Corticosteroids in COVID-19: A Two-edged Sword
        date: 2020-06-25
       words: 3107
      flesch: 43
     summary: The use of corticosteroid as treatment in SARS was associated with adverse outcomes: a retrospective cohort study SARS: systematic review of treatment effects Steroid therapy and the risk of osteonecrosis in SARS patients: a dose-response meta-analysis Treatment of severe acute respiratory syndrome with glucosteroids: the Guangzhou experience Corticosteroid Therapy for Critically Ill Patients with Middle East Respiratory Syndrome Clinical predictors of mortality of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection: A cohort study Corticosteroids as Adjunctive Therapy in the Treatment of Influenza: An Updated Cochrane Systematic Review and Meta-analysis Effect of low-tomoderate-dose corticosteroids on mortality of hospitalized adolescents and adults with influenza A(H1N1)pdm09 viral pneumonia Adjuvant Corticosteroid Treatment in Adults With Influenza A (H7N9) Viral Pneumonia Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury Pathological findings of COVID-19 associated with acute respiratory distress syndrome Clinical features and progression of acute respiratory distress syndrome in coronavirus disease COVID-19 with Different Severity: A Multi-center Study of Clinical Features The Treatment and Outcomes of Patients with COVID-19 in Hubei, China: A Multi-Centered, Retrospective, Observational Study (2/26/2020) [24] So far, whether the patients with COVID-19 could benefit from corticosteroids therapy is not clear.
    keywords: corticosteroids; covid-19; patients; study; therapy; treatment
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        item: #2624 of 7819
          id: cord-284017-1fz90e3k
      author: Henríquez, Josefa
       title: The first months of the COVID-19 pandemic in Spain
        date: 2020-08-27
       words: 5723
      flesch: 53
     summary: Pané-Mena and Pascual (22) list three types of measures implemented on specialist services that included coordination and crisis management measures, support measures refocusing some services exclusively to COVID-19 related cases and referring other series to other centers and logistic measures based on tackling with the lack of devices and materials to provide a suitable healthcare. Another key area to address public health measures consists of the redefinition in the organization of long-term care services.
    keywords: care; cases; covid-19; figure; health; information; measures; ministry; pandemic; spain; spread; system
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        item: #2625 of 7819
          id: cord-284037-nj5jo1ev
      author: Kwee, Thomas C.
       title: Chest CT in COVID-19: What the Radiologist Needs to Know
        date: 2020-10-23
       words: 7673
      flesch: 29
     summary: The authors describe imaging and managing care of patients with COVID-19, with topics including (a) chest CT protocol, (b) chest CT findings of COVID-19 and its complications, (c) the diagnostic accuracy of chest CT and its role in diagnostic decision making and prognostication, and (d) reporting and communicating chest CT findings. In this article, we provide an overview of chest CT in imaging and managing care of patients with COVID-19 and discuss topics including (a) chest CT protocol, (b) chest CT findings in COVID-19 and its complications, (c) the diagnostic accuracy of chest CT and its role in diagnostic decision making and prognostication, and (d) reporting and communicating chest CT findings.
    keywords: chest; chest ct; coronavirus; covid-19; disease; findings; imaging; patients; pcr; pneumonia; sars; test
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        item: #2626 of 7819
          id: cord-284038-93s3ffoy
      author: Keyhanian, Kiandokht
       title: SARS-CoV-2 and nervous system: From pathogenesis to clinical manifestation
        date: 2020-11-07
       words: 11721
      flesch: 30
     summary: Viruses Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways Coupling viruses to dynein and kinesin-1. A first step in understanding SARS pathogenesis Propagation of swine hemagglutinating encephalomyelitis virus and pseudorabies virus in dorsal root ganglia cells Expression of the monoclonal antibody against nucleocapsid antigen of SARS-associated coronavirus in autopsy tissues from SARS patients.
    keywords: acute; brain; case; cells; cns; coronavirus; cov-2; covid-19; csf; disease; encephalitis; et al; human; infection; patients; pcr; r n; receptor; sars; study; symptoms; syndrome; system
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        item: #2627 of 7819
          id: cord-284042-awl5bb0j
      author: Carrascosa, J.M.
       title: Cutaneous Manifestations in the Context of SARS-CoV-2 Infection (COVID-19)()
        date: 2020-10-15
       words: 3954
      flesch: 39
     summary: A description of 74 cases from a tertiary university hospital in Spain Varicella-like exanthem as a specific COVID-19-associated skin manifestation: multicenter case series of 22 patients Clinical and histological characterization of vesicular COVID-19 rashes: A prospective study in a tertiary care hospital Acute urticaria with pyrexia as the first manifestations of a COVID-19 infection Acute urticaria with pyrexia as the first manifestations of a COVID-19 infection: Urticaria-like lesions in COVID-19 patients are not really urticaria. Hedou et al., 9 in response to the aforementioned article, reported skin lesions attributable to COVID-19 in 4.9% of patients with a positive polymerase chain reaction (PCR) test result in a series of 103 patients.
    keywords: cases; cov-2; covid-19; infection; lesions; manifestations; patients; sars; skin; symptoms
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        item: #2628 of 7819
          id: cord-284093-w2ppj0yz
      author: None
       title: Praticiens de la cavité orale. Recommandations professionnelles. Risques infectieux par le COVID-19. Faire front pour faire face
        date: 2020-04-16
       words: 1859
      flesch: 57
     summary: Certains coronavirus causent des infections chez l'homme [4] , le plus souvent associé es à des rhumes et des syndromes grippaux bé nins approchent la bouche de leurs patients, examinent et travaillent dans la bouche des patients.
    keywords: coronavirus; covid-19; d'un; des; les; mains; par; pour
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        item: #2629 of 7819
          id: cord-284097-94pz1601
      author: Korun, Oktay
       title: The impact of COVID‐19 pandemic on congenital heart surgery practice: An alarming change in demographics
        date: 2020-08-13
       words: 1352
      flesch: 55
     summary: According to the results of a newly published survey covering 60 international clinics, the median reduction in patient case volume was between 50% and 70%, in concordance with our outcomes. The purpose of this report is to analyze the effect of the pandemic on the clinical practice of congenital heart surgery in a single center.
    keywords: covid; patients; period; surgery
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        item: #2630 of 7819
          id: cord-284112-jobd5s4l
      author: Tulgar, Serkan
       title: Possible Old Drugs for Repositioning in COVID-19 Treatment: Combating Cytokine Storms from Haloperidol to Anti-interleukin Agents
        date: 2019-06-01
       words: 512
      flesch: 35
     summary: Use of Spironolactone in SARS-CoV-2 ARDS Patients Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro COVID-19: consider cytokine storm syndromes and immunosuppression Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies The cytokine release syndrome (CRS) of severe COVID-19 and Interleukin-6 receptor (IL-6R) antagonist Tocilizumab may be the key to reduce the mortality Tocilizumab treatment in COVID-19: Tocilizumab is available as an effective option in combating cytokine storm.
    keywords: covid-19; treatment
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        item: #2631 of 7819
          id: cord-284130-2q6qmex3
      author: Wu, Xiao
       title: Exposure to air pollution and COVID-19 mortality in the United States: A nationwide cross-sectional study
        date: 2020-04-07
       words: 2800
      flesch: 44
     summary: These spatial patterns in COVID-19 death rates generally mimic patterns in both high population density and high PM 2.5 exposure areas. Early data from China suggests that a majority of COVID-19 deaths occurred in adults aged respiratory distress syndrome (ARDS) which has a mortality rate ranging from 27% to 45%.
    keywords: covid-19; death; exposure; increase; population; preprint
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        item: #2632 of 7819
          id: cord-284152-6aog88cx
      author: Mitchell, Edith Peterson
       title: COVID-19 Innovations: Addressing Rapidly Changing Clinical Needs
        date: 2020-07-21
       words: 601
      flesch: 35
     summary: 3 Myocardial injury and myocarditis are frequently found in patients with COVID-19 disease. The symptoms most frequently reported as related to COVID-19 infection are fatigue, fever, and shortness of breath.
    keywords: covid-19; patients
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        item: #2633 of 7819
          id: cord-284160-sgr8p78v
      author: Satici, Begum
       title: Adaptation of the Fear of COVID-19 Scale: Its Association with Psychological Distress and Life Satisfaction in Turkey
        date: 2020-05-08
       words: 2402
      flesch: 50
     summary: The Fear of COVID-19 Scale: development and initial validation The basics of item response theory (2nd mirt: a multidimensional item response theory package for the R environment The satisfaction with life scale Psychometric properties of the satisfaction with life scale among Turkish university students, correctional officers, and elderly adults Introduction to mediation, moderation, and conditional process analysis: a regressionbased approach The short-form version of the Depression Anxiety Stress Scales (DASS-21): construct validity and normative data in a large non-clinical sample Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives Using Rasch rating scale model to reassess the psychometric properties of the Persian version of the PedsQL TM 4.0 Generic Core Scales in school children Principles and practice of structural equation modeling Social reaction toward the 2019 novel coronavirus (COVID-19) key: cord-284160-sgr8p78v authors: Satici, Begum; Gocet-Tekin, Emine; Deniz, M. Engin; Satici, Seydi Ahmet title: Adaptation of the Fear of COVID-19 Scale: Its Association with Psychological Distress and Life Satisfaction in Turkey date: 2020-05-08 journal: Int J Ment Health Addict DOI: 10.1007/s11469-020-00294-0 sha: doc_id: 284160 cord_uid: sgr8p78v The world is currently experiencing a pandemic of an infectious disease called COVID-19 which has drawn global intensive attention.
    keywords: anxiety; covid-19; fear; satisfaction; scale
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        item: #2634 of 7819
          id: cord-284175-5rre1kbn
      author: Elsaid, Ossama
       title: Ventricular Fibrillation Storm in Coronavirus 2019
        date: 2020-08-29
       words: 1091
      flesch: 29
     summary: The patient had heart failure with reduced ejection fraction and coronary artery disease Coronavirus Disease (COVID-19) Situation Reports Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the Coronavirus Disease 2019 (COVID-19) Pandemic Cardiovascular Implications of Fatal Outcomes of Patients with Coronavirus Disease 2019 (COVID-19) Clinical Characteristics of Covid-19 in Cardiac Arrhythmias in COVID-19 Infection QT interval prolongation and torsade de pointes in patients with COVID-19 treated with hydroxychloroquine/azithromycin In-hospital cardiac arrest outcomes among patients with COVID-19 pneumonia in Wuhan COVID-19 and cardiac arrhythmias 1, 2 Due to the panoply of precipitating factors that can cause cardiac arrhythmia in COVID-19 patients, identifying the underlying culprit is crucial for proper management.
    keywords: covid-19; inflammation; patients; qtc
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        item: #2635 of 7819
          id: cord-284188-ujdla954
      author: Smith, Silas W.
       title: Virtual Urgent Care Quality and Safety in the Time of Coronavirus
        date: 2020-10-16
       words: 5915
      flesch: 46
     summary: VUC patients are not directly comparable with ED patients; various complex factors contribute to decision thresholds to access these various care modalities. We performed a retrospective cohort analysis in a single hospital network of VUC patients from March 1, 2020 through April 20, 2020.
    keywords: care; comorbidities; covid-19; emergency; follow; health; pandemic; patients; period; telehealth; telemedicine; visit; vuc
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        item: #2636 of 7819
          id: cord-284207-i943w5r1
      author: Zidan, Ahmed
       title: Position Statement of Transplant Activity in the Middle East in Era of COVID-19 Pandemic
        date: 2020-06-23
       words: 1955
      flesch: 46
     summary: Living donor liver transplants were placed on hold at the end of March, and only emergency procedures have been considered. Deceased donor transplants continue, though the numbers have dropped.
    keywords: covid-19; donor; liver; patients; transplant
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        item: #2637 of 7819
          id: cord-284217-tv8f1315
      author: Qazi, Javaria
       title: Evolution to Online Education around the globe during a SARS-CoV-2 Coronavirus (COVID-19) Pandemic: Do develop and underdeveloped cope alike?
        date: 2020-10-13
       words: 3070
      flesch: 41
     summary: Outcomes suggest that use and access to online learning resources during novel infectious disease a SARS-CoV-2 Coronavirus (COVID-19) Pandemic is crucial for student satisfaction. The study mainly aims to assess the effect of access & use of online learning resources amid the COVID-19 lockdown on student satisfaction.
    keywords: covid-19; learning; online; satisfaction; students; use
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        item: #2638 of 7819
          id: cord-284220-55mckelv
      author: batista, m.
       title: Estimation of a state of Corona 19 epidemic in August 2020 by multistage logistic model: a case of EU, USA, and World
        date: 2020-09-02
       words: 2211
      flesch: 52
     summary: The Lancet A mathematical model for the novel coronavirus epidemic in Wuhan Rational evaluation of various epidemic models based on the COVID-19 data of China. medRxiv Estimating the size of COVID-19 epidemic outbreak A New Adaptive Logistic Model for Epidemics and the Resurgence of COVID-19 in the United States.
    keywords: covid-19; epidemic; medrxiv; model; preprint
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        item: #2639 of 7819
          id: cord-284234-9cd2v6bt
      author: Sebastian, S
       title: Safety of drugs during previous and current coronavirus pandemics: Lessons for IBD
        date: 2020-06-10
       words: 4490
      flesch: 29
     summary: One of the key challenges needing addressing is the quantification of the risks of immunosuppressive and biologic therapies in IBD patients during the pandemic. Although clinical, immunological and pharmacological data from the experience with the previous coronavirus outbreaks cannot be automatically translated to predict the safety of IBD therapies during COVID-19 pandemic, the signals so far from these outbreaks on IBD patients who are on immunomodulators and biologics are reassuring to patients and clinicians alike.
    keywords: bowel; coronavirus; covid-19; disease; ibd; infection; mers; patients; risk; sars
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        item: #2640 of 7819
          id: cord-284251-brn5izwo
      author: Melmed, Kara R.
       title: Risk factors for intracerebral hemorrhage in patients with COVID-19
        date: 2020-09-24
       words: 3643
      flesch: 37
     summary: In ICH patients, the indication for therapeutic anticoagulation was elevated D-dimer in 18 (54.5%) patients, while this was the indication in only 14.9% of patients without ICH (p < 0.001). Patients with ICH who were on therapeutic anticoagulation had a non-statistically significant higher mortality than ICH patients who were not on anticoagulation (14 vs To further determine the predictive value of markers of coagulation for ICH, the ROC curve for coagulation abnormalities was plotted (Fig. 2) .
    keywords: anticoagulation; covid-19; hemorrhage; ich; neuroimaging; patients; risk; use
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        item: #2641 of 7819
          id: cord-284257-zplfyqqi
      author: Mocco, J
       title: In Reply: May Cooler Heads Prevail During a Pandemic: Stroke in COVID-19 Patients or COVID-19 in Stroke Patients?
        date: 2020-08-28
       words: 2348
      flesch: 44
     summary: Letter: may cooler heads prevail during a pandemic: stroke in COVID-19 patients or COVID-19 in stroke patients? However, stroke as the presenting complaint of COVID-19 patients with otherwise mild or no systemic disease raises concerns over COVID-19 being a bystander given its high prevalence in reporting regions.
    keywords: alawieh; covid-19; patients; spiotta; stroke
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        item: #2642 of 7819
          id: cord-284272-68ykes60
      author: Suso-Ribera, Carlos
       title: How Much Support Is There for the Recommendations Made to the General Population during Confinement? A Study during the First Three Days of the COVID–19 Quarantine in Spain
        date: 2020-06-18
       words: 5400
      flesch: 42
     summary: Additionally, answers from three consecutive days were collapsed, which prevents us from exploring whether the correlation between study variables differed across days. As anticipated, the mood of a sample of individuals at quarantine onset was generally poorer compared to a sample of individuals from the general population recruited before the current COVID-19 [17] .
    keywords: covid-19; mood; participants; quarantine; study; variables
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        item: #2643 of 7819
          id: cord-284274-9uu7yflt
      author: Russi, Christopher S.
       title: Emergency Medicine Telehealth for COVID-19: Minimize Front-Line Provider Exposure and Conserve Personal Protective Equipment (PPE)
        date: 2020-08-13
       words: 1612
      flesch: 43
     summary: Our purpose is to outline current Mayo Clinic strategies harnessing telehealth solutions for COVID-19 emergency preparedness and acute emergency care . Telehealth opens the door to new models of acute emergency care.
    keywords: care; covid-19; emergency; patients; ppe; telehealth
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        item: #2644 of 7819
          id: cord-284298-tcied4l5
      author: Ojeahere, Margaret Isioma
       title: Management of psychiatric conditions and delirium during the COVID-19 pandemic across continents: The lessons thus far
        date: 2020-09-19
       words: 6819
      flesch: 32
     summary: Lebanon has included hydroxychloroquine as part of the regimen used for COVID-19 patients in the ICU. The Thai village health volunteers have played important roles, not only for COVID-19 patients but in providing healthcare generally.
    keywords: care; cases; conditions; countries; covid-19; delirium; et al; health; management; pandemic; patients; psychiatric; r n
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        item: #2645 of 7819
          id: cord-284301-fg3hk94b
      author: Umemura, Yutaka
       title: Hematological Phenotype of COVID-19-Induced Coagulopathy: Far from Typical Sepsis-Induced Coagulopathy
        date: 2020-09-05
       words: 3721
      flesch: 34
     summary: According to these insights, our results suggested that systemic hypercoagulation was hardly induced by COVID-19 infection, but the risk of local thrombus formation increased in the acute phase of severe COVID-19 pneumonia. COVID-19 patients had moderately high levels of thrombin–antithrombin complex and plasmin-alpha2-plasmin inhibitor complex but normal plasminogen activator inhibitor-1 level.
    keywords: coagulopathy; covid-19; dic; group; non; patients; time
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        item: #2646 of 7819
          id: cord-284302-odvv2yn3
      author: Minagorre, Pedro J. Alcalá
       title: CAMBIOS A PARTIR DE LA COVID-19. UNA PERSPECTIVA DESDE LA PEDIATRÍA INTERNA HOSPITALARIA
        date: 2020-06-19
       words: 3135
      flesch: 36
     summary: Durante la primera etapa de la epidemia Con respecto a la incertidumbre de algunos aspectos terapéuticos de la COVID-19, los parámetros para iniciar tratamientos sin indicación establecida son, aparte de la imposibilidad inmediata para llevar a cabo ensayos clínicos, el tener referencia de la inocuidad en animales, un adecuado análisis riesgo-beneficio por los comités de ética de investigación y el consentimiento informado por el paciente o tutores legales.
    keywords: adultos; con; covid-19; crisis; del; esta; hospital; hospitalaria; las; los; pacientes; para; pediatría; personal; por; que; sars; una
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        item: #2647 of 7819
          id: cord-284327-psz2usnx
      author: Banda, J.
       title: KNOWLEDGE AND BEHAVIORS RELATED TO THE COVID-19 PANDEMIC IN MALAWI
        date: 2020-06-18
       words: 3710
      flesch: 52
     summary: Close to half of study respondents perceived themselves at a low risk of acquiring the novel coronavirus. Knowledge of transmission patterns was more limited among rural respondents for 3 of the 5 questions that were asked.
    keywords: covid-19; license; medrxiv; preprint; respondents
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        item: #2648 of 7819
          id: cord-284335-bz3y03y0
      author: Ng, Janice Natasha
       title: The Aftermath of COVID‐19 in Dermatology Practice: What's next?
        date: 2020-06-05
       words: 1047
      flesch: 44
     summary: Recently, skin changes such as erythematous rash, widespread urticaria and even varicella-like vesicles were reported in COVID-19 patients. The increasing number of confirmed COVID-19 cases emphasized the importance of preventive measures among healthcare workers (HCWs).
    keywords: covid-19; patients; practice
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        item: #2649 of 7819
          id: cord-284342-y9tq7o0v
      author: Liu, Qian
       title: Associations between serum amyloid A, interleukin‐6, and COVID‐19: A cross‐sectional study
        date: 2020-08-28
       words: 2273
      flesch: 39
     summary: SAA, IL‐6, and NLR were significantly higher in patients with COVID‐19 (all P < .001), and compared with nonsevere patients, three indicators of severe patients were significantly elevated. Meanwhile, our study also indicated that PLR was significantly higher in severe patients than that of healthy group and nonsevere patients.
    keywords: coronavirus; count; covid-19; disease; group; patients
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        item: #2650 of 7819
          id: cord-284353-f7zkp9cf
      author: Sheikh, Aziz
       title: Reopening schools after the COVID-19 lockdown
        date: 2020-06-27
       words: 1141
      flesch: 49
     summary: key: cord-284353-f7zkp9cf authors: Sheikh, Aziz; Sheikh, Asiyah; Sheikh, Zakariya; Dhami, Sangeeta title: Reopening schools after the COVID-19 lockdown date: 2020-06-27 journal: Journal of global health DOI: 10.7189/jogh.10.010376 sha: doc_id: 284353 cord_uid: f7zkp9cf nan W ith nationwide school closures currently operating in 191 countries, the United Nations Educational, Scientific and Cultural Organization (UNESCO) has estimated that 1.6 billion (90.2%) students are currently out of primary, secondary and tertiary education (henceforth schools) as a result of the global COVID-19 lockdown A recent systematic review on school closures, which drew primarily on the evidence base from severe acute respiratory syndrome (SARS), concluded that around 2-4% of COVID-19 deaths could be prevented as a result of school closures [7] .
    keywords: children; covid-19; school
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        item: #2651 of 7819
          id: cord-284365-g46myqe7
      author: Guo, Qian
       title: Immediate psychological distress in quarantined patients with COVID-19 and its association with peripheral inflammation: a mixed-method study
        date: 2020-05-19
       words: 4765
      flesch: 39
     summary: Future research could focus on the mediating role of coping strategies and gender differences in the stress-related symptoms of patients, and the cause and consequence of the stigma associated with the psychopathology symptoms of COVID-19 patients. Results revealed that COVID-19 patients, when compared to non-COVID controls, manifested higher levels of depression (P < 0.001), anxiety (P < 0.001), and post-traumatic stress symptoms (P < 0.001).
    keywords: covid-19; depression; et al; levels; patients; stress; study; symptoms
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        item: #2652 of 7819
          id: cord-284385-ster02o9
      author: Gambichler, Thilo
       title: On the use of immune checkpoint inhibitors in patients with viral infections including COVID-19
        date: 2020-07-01
       words: 7170
      flesch: 33
     summary: The INVIDIa study State of the art about influenza vaccination for advanced cancer patients receiving immune checkpoint inhibitors: when common sense is not enough Severe relapse of vaccineinduced Guillain-Barré syndrome after treatment with nivolumab Pd-1 blockade in rhesus macaques: impact on chronic infection and prophylactic vaccination Safety of inactivated influenza vaccine in cancer patients receiving immune checkpoint inhibitors Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity Influenza vaccination of cancer patients during PD-1 blockade induces serological protection but may raise the risk for immune-related adverse events Immune-Mediated adverse events following influenza vaccine in cancer patients receiving immune checkpoint inhibitors Influenza vaccination in patients with lung cancer receiving anti-programmed death receptor 1 immunotherapy does not induce immune-related adverse events Safety of influenza vaccine in patients with cancer receiving pembrolizumab Immune-Related adverse events in patients with cancer receiving influenza vaccination and immune checkpoint inhibitors Immunogenicity of influenza vaccination in patients with cancer receiving immune checkpoint inhibitor Influenza vaccination and myocarditis among patients receiving immune checkpoint inhibitors Single-cell RNA-seq identifies a PD-1 hi ILC progenitor and defines its development pathway COVID-19 Dashboard by the center for systems science and engineering (CSSE) at Johns Hopkins University (JHU) Covid-19: risk factors for severe disease and death Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19) key: cord-284385-ster02o9 authors: Gambichler, Thilo; Reuther, Judith; Scheel, Christina H; Becker, Jürgen Christian title: On the use of immune checkpoint inhibitors in patients with viral infections including COVID-19 date: 2020-07-01 journal: J Immunother Cancer DOI: 10.1136/jitc-2020-001145 sha: doc_id: 284385 cord_uid: ster02o9 The present review summarizes up-to-date evidence addressing the frequently discussed clinical controversies regarding the use of immune checkpoint inhibitors (ICIs) in cancer patients with viral infections, including AIDS, hepatitis B and C, progressive multifocal leukoencephalopathy, influenza, and COVID-19.
    keywords: cancer; cell; checkpoint; covid-19; hepatitis; hiv; ici; immune; infection; influenza; inhibitors; lymphocytes; patients; pd-1; treatment
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        item: #2653 of 7819
          id: cord-284393-s9qp9a4e
      author: Wei, Yiping
       title: Clinical characteristics of 276 hospitalized patients with coronavirus disease 2019 in Zengdu District, Hubei Province: a single-center descriptive study
        date: 2020-07-29
       words: 4272
      flesch: 48
     summary: In terms of laboratory tests, 75% of patients had lymphopenia, and more obvious findings were noted in severe patients. [14] showed that the age of severe patients was significantly older than that of non-severe patients.
    keywords: characteristics; clinical; coronavirus; covid-19; disease; hospital; patients; study; wuhan
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        item: #2654 of 7819
          id: cord-284398-rhfwbyav
      author: Aboubakr, Hamada A.
       title: Stability of SARS‐CoV‐2 and other coronaviruses in the environment and on common touch surfaces and the influence of climatic conditions: A review
        date: 2020-07-14
       words: 6436
      flesch: 43
     summary: The effects of temperature and relative humidity on the viability of the SARS coronavirus SARS-CoV-2-positive sputum and feces after conversion of pharyngeal samples in patients with COVID-19 Viral replication in the nasopharynx is associated with diarrhea in patients with severe acute respiratory syndrome Stability of SARS-CoV-2 in different environmental conditions The SRAS-COV-2 nucleic acid detected for the first time on the surface of door handle in Guangzhou and cleaning taken attention Physico-chemical properties of murine hepatitis virus, strain A59 Inactivation of the coronavirus that induces severe acute respiratory syndrome, SARS-CoV Building a COVID-19 Vulnerability Index SARS-CoV-2: A novel deadly virus in a globalised world Identification of a novel coronavirus in patients with severe acute respiratory syndrome Stability of SARS coronavirus in human specimens and environment and its sensitivity to heating and UV irradiation The effect of UVB irradiation on antibody responses during herpes simplex virus type 1 (HSV-1) infections of mice. No Evidence for Temperature-Dependence of the COVID-19 Epidemic Coronavirus Resource Center Inactivation of SARS coronavirus by means of povidone-iodine, physical conditions and chemical reagents Changes to taxonomy and the international code of virus classification and nomenclature ratified by the international committee on taxonomy of viruses Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period Reduced antigen-presenting function of human Epstein-Barr virus (EBV)-B cells and monocytes after UVB radiation is accompanied by decreased expression of B7, intercellular adhesion molecule-1 (ICAM-1) and LFA-3 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and corona virus disease-2019 (COVID-19): The epidemic and the challenges Survival of severe acute respiratory syndrome coronavirus Effect of pH and temperature on the infectivity of human coronavirus 229E Thermal inactivation studies of a coronavirus, transmissible gastroenteritis virus Heat inactivation of the Middle East respiratory syndrome coronavirus.
    keywords: coronavirus; cov-2; covid-19; days; et al; human; sars; study; temperature; transmission; virus
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        item: #2655 of 7819
          id: cord-284403-f8s4123u
      author: Becq, Aymeric
       title: Drastic decrease of urgent endoscopies outside regular working hours during the Covid-19 pandemic in the paris area
        date: 2020-08-04
       words: 4288
      flesch: 49
     summary: Outside regular hours (i.e. nights, weekends and public holidays), urgent endoscopy acts are usually performed by four different on-call teams. We have recently published on how urgent endoscopy acts were carried out in an extended area during the COVID-19 pandemic (11) .
    keywords: acts; covid-19; endoscopy; number; pandemic; patients; study
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        item: #2656 of 7819
          id: cord-284424-6gljl7n5
      author: Brown, Eric E.
       title: Anticipating and Mitigating the Impact of COVID-19 Pandemic on Alzheimer's Disease and Related Dementias
        date: 2020-04-18
       words: 5004
      flesch: 39
     summary: We discuss and propose mitigation strategies for: the risk of COVID-19 infection and its associated morbidity and mortality for individuals with ADRD; the impact of COVID-19 on the diagnosis and clinical management of ADRD; consequences of societal responses to COVID-19 in different ADRD care settings; the effect of COVID-19 on caregivers and physicians of individuals with ADRD; mental hygiene, trauma, and stigma in the time of COVID-19; and the potential impact of COVID-19 on ADRD research. As with any major crisis, the COVID-19 pandemic will have a lasting impact on the way all clinical research, including ADRD research, is carried out.
    keywords: adrd; care; covid-19; dementia; health; individuals; pandemic; patients; risk; work
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        item: #2657 of 7819
          id: cord-284449-z7r4n0w7
      author: Ma, L.
       title: Effect of SARS-CoV-2 infection upon male gonadal function: A single center-based study
        date: 2020-03-24
       words: 2859
      flesch: 47
     summary: Clinical characteristics of 81 male patients with COVID-19 COVID-19 patients median (25 th ~75 th percentile) -yrs , range) White blood cell count Lymphocyte Alanine transaminase (ALT, IU/L) 43 (13~799) Although serum testosterone levels did not statistically change in the COVID-19 group, a significant increase in serum LH level and a dramatic decrease in serum T: LH were observed.
    keywords: cov-2; covid-19; sars; serum; study
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        item: #2658 of 7819
          id: cord-284453-topozldw
      author: Dimri, V. P.
       title: Understanding Trend of the Covid-19 Fatalities in India
        date: 2020-06-17
       words: 1800
      flesch: 55
     summary: Shows total COVID-19 deaths in India and simulation of COVID-19 deaths with confidence intervals of 95% (red curve). Please note that the number of confirmed cases is dependent on how much testing has been done, hence we choose to further analyze reported number of COVID-19 death cases, which are much more reliable numbers, than the infected cases.
    keywords: cases; covid-19; data; deaths; number
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        item: #2659 of 7819
          id: cord-284470-so8bq046
      author: Coe, Taylor M.
       title: Practical Techniques to Adapt Surgical Resident Education to the COVID-19 Era
        date: 2020-04-29
       words: 467
      flesch: 28
     summary: Daodu and colleagues provide an insightful overview of the general implications that COVID-19 has on surgical education. In conclusion, a multi-faceted approach to virtual surgical education during the COVID-19 pandemic is feasible and can meet the educational needs of surgical residents amidst the current constraints.
    keywords: covid-19; education
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        item: #2660 of 7819
          id: cord-284494-4klrtjpb
      author: Handoko
       title: Ensuring Safety and Sustainability of Radiotherapy Services during the COVID-19 Pandemic in Resources Constrain Country: An Indonesian Experience
        date: 2020-06-06
       words: 1671
      flesch: 40
     summary: This article describes the Indonesian experience in ensuring sustainability of radiotherapy services during the pandemic, highlighting various important adjustments which were made to allow radiotherapy centers nationwide to continue operating while protecting staff and patients from the risk of disease transmission. We will share our perspectives on how radiotherapy centers nationwide in Indonesia respond to this crisis.
    keywords: centers; covid-19; pandemic; radiotherapy; treatment
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        item: #2661 of 7819
          id: cord-284498-54j6ys8s
      author: Ihsanullah, Ihsanullah
       title: Coronavirus 2 (SARS-CoV-2) in water environments: Current status, challenges and research opportunities
        date: 2020-10-16
       words: 5704
      flesch: 40
     summary: Although the major transmission routes of SARS-CoV-2 are through respiratory droplets and direct contact [3] [4] [5] , recent studies have reported the presence of viral RNA of SARS-CoV-2 in untreated and treated wastewater and human feces [3, [6] A recent study reported that there is a negative correlation between sunlight UV dose and percent positive of SARS-CoV-2 [117] .
    keywords: cov-2; covid-19; detection; potential; presence; research; sars; sewage; transmission; treatment; virus; wastewater; wwtps
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        item: #2662 of 7819
          id: cord-284519-cufyqv7h
      author: Singu, Sravani
       title: Impact of Social Determinants of Health on the Emerging COVID-19 Pandemic in the United States
        date: 2020-07-21
       words: 7915
      flesch: 52
     summary: Patients who demonstrate low health literacy may have high overall literacy and high verbal fluency, which causes the patient to present as having high health literacy. Low health literacy can cause patients difficulty with navigating the complex healthcare system and understanding medical advice or prescriptions.
    keywords: access; care; covid-19; distancing; education; food; health; income; individuals; neighborhoods; pandemic; risk; study
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        item: #2663 of 7819
          id: cord-284526-a5kgo4ct
      author: Gavriilaki, Eleni
       title: Endothelial Dysfunction in COVID-19: Lessons Learned from Coronaviruses
        date: 2020-08-27
       words: 6013
      flesch: 26
     summary: Translational lessons from animal models Central nervous system involvement by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Clin Microbiol Infect: the official publication of the European Society of Clinical Microbiology and Infectious Diseases COVID-19-associated acute hemorrhagic necrotizing encephalopathy: CT and MRI features A first case of meningitis/encephalitis associated with SARS-Coronavirus-2 Acute disseminated encephalomyelitis after SARS-CoV-2 infection Severe COVID-19 infection and thrombotic microangiopathy: success does not come easily A case-series study describing a possible pathophysiologic mechanism of severe COVID-19 infection unravelled the catastrophic microvascular injury syndrome mediated by complement cascade Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19 Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis Post-mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction Autopsy findings and venous thromboembolism in patients with COVID-19 Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Pulmonary embolism in COVID-19 patients: awareness of an increased prevalence Incidence of venous thromboembolism in hospitalized patients with COVID-19 High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan Systematic assessment of venous thromboembolism in COVID-19 patients receiving thromboprophylaxis: incidence and role of D-dimer as predictive factors Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum Scientific and standardization committee communication: clinical guidance on the diagnosis, prevention and treatment of venous thromboembolism in hospitalized patients with COVID In parallel with autopsy findings, high rates of VTE (10 to 43%, especially PE) have been clinically diagnosed in COVID-19 patients in intensive care units (ICUs)
    keywords: acute; case; coronavirus; covid-19; disease; dysfunction; endothelial; icu; infection; patients; sars; study; syndrome
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        item: #2664 of 7819
          id: cord-284529-0ri4kw4k
      author: Håkansson, Anders
       title: Impact of COVID-19 on Online Gambling – A General Population Survey During the Pandemic
        date: 2020-09-25
       words: 5987
      flesch: 45
     summary: The present study had the intention to include online gamblers, i.e., individuals with a certain degree of online gambling behavior (ten or more occasions during the past-year), given the high prevalence of online gambling and in order to provide a new measure to compare to a previous online gambling study carried out in the present setting (Håkansson and Widinghoff, 2020) . Given the need for objective data about gambling behavior during the pandemic, the present analysis, from a project assessing online gambling in Sweden, aimed to study past-30-day gambling patterns in online gamblers in Sweden.
    keywords: betting; covid-19; gamblers; gambling; land; online; sports; study; types
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        item: #2665 of 7819
          id: cord-284545-vn60yd46
      author: Sanyaolu, Adekunle
       title: Comorbidity and its Impact on Patients with COVID-19
        date: 2020-06-25
       words: 3752
      flesch: 50
     summary: In the USA, the Centers for Disease Control and Prevention (CDC) uses COVID-NET in 14 states to monitor the demographics of COVID-19 patients who are being hospitalized [6] . A meta-analysis study of COVID-19 patients, as depicted in Fig. 1 , showed fever (88.8%) as the most common symptom, followed by dry cough (68%) and fatigue (33%)
    keywords: comorbidities; coronavirus; covid-19; diabetes; disease; patients; risk
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        item: #2666 of 7819
          id: cord-284555-5qbigvun
      author: Kent, David M.
       title: When predictions are used to allocate scarce health care resources: three considerations for models in the era of Covid-19
        date: 2020-05-20
       words: 1761
      flesch: 33
     summary: Allocation of these resources to those most likely to benefit can be supported by clinical prediction models. While development of accurate clinical prediction models is important to ensure that the greatest benefit can be derived from a limited supply of life-saving resources, we should acknowledge that there will not be a perfect technical solution to this problem or a single best method of resource allocation
    keywords: decision; models; prediction; resources
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        item: #2667 of 7819
          id: cord-284566-u0elncex
      author: Siu, Henry Yu-Hin
       title: A cross-sectional survey assessing the preparedness of the long-term care sector to respond to the COVID-19 pandemic in Ontario, Canada
        date: 2020-10-22
       words: 4214
      flesch: 41
     summary: However, the rapid spread of COVID-19 and the overwhelming rate of mortality observed in Ontario LTC homes raises important questions about the preparedness and readiness of, and the sufficiency and timeliness of communication with LTC homes during the pandemic. An online cross-sectional survey of Ontario LTC Clinicians working in LTC homes in Ontario Canada was conducted to provide the clinician perspective on the preparedness and engagement of the LTC sector during the COVID-19 pandemic.
    keywords: care; covid-19; health; homes; ltc; ontario; pandemic; respondents; survey
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        item: #2668 of 7819
          id: cord-284573-w0sk622m
      author: Caduff, Carlo
       title: What Went Wrong: Corona and the World after the Full Stop
        date: 2020-07-21
       words: 9279
      flesch: 55
     summary: But health care workers deserve more than patriotic feelings and symbolic gestures; they deserve better health care policies. Outsourced production capacity and insufficient stockpiles of personal protective equipment put nursing home residents, community health care workers, and hospital staff at risk, weakening health care systems further.
    keywords: care; case; countries; covid-19; deaths; disease; health; lockdown; pandemic; people; public; rate; response; testing; virus; world
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        item: #2669 of 7819
          id: cord-284576-nemh4wdo
      author: Sims, Jonathan T.
       title: Characterization of the Cytokine Storm Reflects Hyperinflammatory Endothelial Dysfunction in COVID-19
        date: 2020-09-10
       words: 1652
      flesch: 22
     summary: Proceedings of the National Academy of 254 Sciences CCR2 and CXCR3 agonistic chemokines are differently expressed and regulated in human 257 alveolar epithelial cells type II A systems approach to inflammation identifies therapeutic targets in SARS-260 CoV-2 infection Remdesivir in adults with severe 262 COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial Comparison of an ordinal endpoint to time-to-event, longitudinal, and binary endpoints for use in 266 evaluating treatments for severe influenza requiring hospitalization Anticoagulant treatment is associated with 269 decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Prevalence of venous thromboembolism in patients 272 with severe novel coronavirus pneumonia Thromboembolic risk and anticoagulant therapy in COVID-19 patients: emerging evidence and 275 call for action Soluble 277 CD40 ligand, interleukin (IL)-6, and hemostatic parameters in metabolic syndrome patients with 278 and without overt ischemic heart disease Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular 283 diseases: the therapeutic potential of PARP inhibitors key: cord-284576-nemh4wdo authors: Sims, Jonathan T.; Krishnan, Venkatesh; Chang, Ching-Yun; Engle, Sarah M.; Casalini, Giacomo; Rodgers, George H.; Bivi, Nicoletta; Nickoloff, Brian J.; Konrad, Robert J.; de Bono, Stephanie; Higgs, Richard E.; Benschop, Robert J.; Ottaviani, Silvia; Cardoso, Anabela; Nirula, Ajay; Corbellino, Mario; Stebbing, Justin title: Characterization of the Cytokine Storm Reflects Hyperinflammatory Endothelial Dysfunction in COVID-19 date: 2020-09-10 journal: J Allergy Clin Immunol DOI: 10.1016/j.jaci.2020.08.031 sha: doc_id: 284576 cord_uid: nemh4wdo Background Physicians treating COVID-19 patients increasingly believe that the hyperinflammatory acute stage of COVID-19 results in a cytokine storm.
    keywords: biomarkers; covid-19; cytokine; fig; patients
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        item: #2670 of 7819
          id: cord-284596-kxioojck
      author: Belvis, Robert
       title: Headaches During COVID‐19: My Clinical Case and Review of the Literature
        date: 2020-05-15
       words: 2392
      flesch: 51
     summary: key: cord-284596-kxioojck authors: Belvis, Robert title: Headaches During COVID‐19: My Clinical Case and Review of the Literature date: 2020-05-15 journal: Headache DOI: 10.1111/head.13841 sha: doc_id: 284596 cord_uid: kxioojck OBJECTIVE: To analyze headaches related to COVID‐19 based on personal case experience. Additionally, other headaches appeared in this first phase of the disease.
    keywords: coronavirus; covid-19; headache; patients; sars; studies
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        item: #2671 of 7819
          id: cord-284598-ksoonwf9
      author: Liu, Shan
       title: Mesenchymal stem cells as a potential therapy for COVID-19
        date: 2020-05-04
       words: 1721
      flesch: 35
     summary: The dynamic data for COVID-19 epidemic worldwide Incidence and outcomes of acute lung injury Mesenchymal stem cell-based therapy of inflammatory lung diseases: current understanding and future perspectives Clinical application of mesenchymal stem cell-derived extracellular vesicle-based therapeutics for inflammatory lung diseases Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs Proteolytic potential of the MSC exosome proteome: implications for an exosome-mediated delivery of therapeutic proteasome Human mesenchymal stem cells modulate allogeneic immune cell responses Human mesenchymal stem cells modulate B-cell functions Conditioned media from mesenchymal stromal cells restore sodium transport and preserve epithelial permeability in an in vitro model of acute alveolar injury Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37 Mitochondrial transfer from bone-marrowderived stromal cells to pulmonary alveoli protects against acute lung injury Acute respiratory distress syndrome: the Berlin definition Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung Fifty years of research in ARDS. Biology and potential therapeutic value Mesenchymal stromal cells for the prophylaxis and treatment of graft-versus-host disease-a meta-analysis Mesenchymal stromal cell treatment prevents H9N2 avian influenza virus-induced acute lung injury in mice Human mesenchymal stromal cells reduce influenza a H5N1-associated acute lung injury in vitro and in vivo Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model In vivo effects of mesenchymal stromal cells in two patients with severe acute respiratory distress syndrome News conference for joint prevention and control measure of COVID-19 by China's State Council Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
    keywords: acute; ards; cells; covid-19; mesenchymal; mscs
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        item: #2672 of 7819
          id: cord-284640-tl9nmvog
      author: Tabah, Alexis
       title: Personal protective equipment and intensive care unit healthcare worker safety in the COVID-19 era (PPE-SAFE): An international survey
        date: 2020-06-13
       words: 3274
      flesch: 52
     summary: In summary this survey study provides a snapshot of reported PPE practices availability, and confidence in adequacy to provide protection among HCWs at the frontlines of the COVID-19 pandemic. Furthermore, shortages of PPE equipment has led to practices to reduce, reuse, or substitute lesser or non-approved products in an attempt to address inadequate supply of PPE (18) .
    keywords: care; covid-19; equipment; hcw; ppe; respondents; survey; use
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        item: #2673 of 7819
          id: cord-284671-r4m1wrbk
      author: Racine, Nicole
       title: Evidence suggests children are being left behind in COVID-19 mental health research
        date: 2020-11-05
       words: 986
      flesch: 48
     summary: Although we anticipate that child mental health researchers worldwide have heeded the call to conduct research that will inform child mental health policy and practice, the chronic underfunding of child mental health research makes this process onerous and can result in delays in research execution as a result. Child mental health research is drastically lagging behind research on adults, and there is an urgent need to prioritize funding for research initiatives that explicitly examines children's mental health.
    keywords: children; health; research
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        item: #2674 of 7819
          id: cord-284734-qioy7eso
      author: Pourahmad, Ramtin
       title: Efficacy of Plasmapheresis and Immunoglobulin Replacement Therapy (IVIG) on Patients with COVID-19
        date: 2020-07-31
       words: 3077
      flesch: 40
     summary: 4433 cases Experience of using convalescent plasma for severe acute respiratory syndrome among healthcare workers in a Taiwan hospital Treatment with convalescent plasma for COVID-19 patients in Wuhan The convalescent sera option for containing COVID-19 Molecular mechanism for antibody-dependent enhancement of coronavirus entry Extensive complement-dependent enhancement of HIV-1 by autologous non-neutralising antibodies at early stages of infection Antibodydependent enhancement of Ebola virus infection The convalescent sera option for containing COVID-19 Management of COVID-19 virus infection by convalescent plasma Immune-epidemiological parameters of the novel coronavirus -a perspective Temporal dynamics in viral shedding and transmissibility of COVID-19 Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Acknowledgments Based on these reports, the administration of plasmapheresis and IVIG should be promptly administered to COVID-19 patients in order to have the highest efficacy in their treatment [7, 26, 27] .
    keywords: convalescent; covid-19; immunoglobulin; ivig; patients; plasmapheresis; therapy; treatment
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        item: #2675 of 7819
          id: cord-284756-jhwd6q0c
      author: Baddour, Khalil
       title: Potential impact of the COVID‐19 pandemic on financial toxicity in cancer survivors
        date: 2020-04-28
       words: 3603
      flesch: 37
     summary: What people (and policymakers) can do about losing coverage during the COVID-19 crisis Battling cancer and the recession Intersecting U.S. epidemics: COVID-19 and lack of health insurance Out-of-pocket costs and oral cancer medication discontinuation in the elderly Determinants of patient-centered financial stress in patients with locally advanced head and neck cancer Association of socioeconomic and practical unmet needs with self-reported nonadherence to cancer treatment appointments in lowincome Latino and black cancer patients Patient and plan characteristics affecting abandonment of oral oncolytic prescriptions The impact of economic recession on the incidence and treatment of cancer Worry about daily financial needs and food insecurity among cancer survivors in the United States Economic downturns, universal health coverage, and cancer mortality in high-income and middle-income countries, 1990-2010: a longitudinal analysis Economic recession and mental health: some conceptual issues Suicide, deprivation, and unemployment: record linkage study Economic suicides in the great recession in Europe and North America Incidence of suicide in persons with cancer Suicide among cancer patients Suicide risk among cancer survivors: head and neck versus other cancers Cancer care in the time of COVID-19 Understanding financial hardship among cancer survivors in the United States: strategies for prevention and mitigation What should palliative Care's response be to the COVID-19 epidemic? key: cord-284756-jhwd6q0c authors: Baddour, Khalil; Kudrick, Lauren D.; Neopaney, Aakriti; Sabik, Lindsay M.; Peddada, Shyamal D.; Nilsen, Marci L.; Johnson, Jonas T.; Ferris, Robert L.; Mady, Leila J. title: Potential impact of the COVID‐19 pandemic on financial toxicity in cancer survivors date: 2020-04-28 journal: Head Neck DOI: 10.1002/hed.26187 sha: doc_id: 284756 cord_uid: jhwd6q0c BACKGROUND: In the context of COVID‐19, cancer survivors represent a particularly vulnerable population that may be “doubly hit” by both costs of cancer treatment and financial strain imposed by the pandemic.
    keywords: cancer; care; covid-19; health; pandemic; patients; survivors; toxicity; treatment
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        item: #2676 of 7819
          id: cord-284782-51mbq7qb
      author: Huang, Jing
       title: Care for the psychological status of frontline medical staff fighting against COVID-19
        date: 2020-04-03
       words: 314
      flesch: 39
     summary: More medical teams were then sent out to the hardest-hit areas in Hubei province, including rescue and medical teams from different provinces, the army medical teams, specialized doctors and nurses' teams, and emergency medical teams from different hospitals. For example, the emergency medical team from the Second Xiangya Hospital is able to set up field hospitals and ambulances to help and serve the With the increasing spreading of the virus worldwide, COVID-19 outbreak is now becoming a pandemic.
    keywords: covid-19
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        item: #2677 of 7819
          id: cord-284786-pua14ogz
      author: Coker, Eric S.
       title: The Effects of Air Pollution on COVID-19 Related Mortality in Northern Italy
        date: 2020-08-04
       words: 7051
      flesch: 36
     summary: The obvious difference between their study and ours is that we used a surrogate excess mortality measure due to the issues of reliability for COVID-19 death data, as we have already discussed. A separate empirical analysis by Becchetti et al. (2020) finds preliminary evidence that confirms such a positive effect of air pollution on mortality in Italy based on the analysis of death data at the province level.
    keywords: air; covid-19; data; deaths; effects; et al; excess; exposure; italy; model; mortality; municipalities
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        item: #2678 of 7819
          id: cord-284804-6i5zbmm1
      author: Pan, Feng
       title: Factors associated with death outcome in patients with severe coronavirus disease-19 (COVID-19): a case-control study
        date: 2020-05-18
       words: 4632
      flesch: 46
     summary: The consecutive admission records were reviewed retrospectively for the period from 27 January 2020 to 19 Regular bedside chest digital radiographs (DRs) were regularly performed every 1 to 3 days instead of conventional computed tomography (CT) scans after admission owing to the risk during the transfer of severe patients. Therefore, the dynamic monitoring of these laboratory parameters could estimate the prognosis in clinical practice for severe patients.
    keywords: admission; course; covid-19; death; event; group; lymphocyte; patients; study
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        item: #2679 of 7819
          id: cord-284820-29uiq6at
      author: Wang, Junfeng
       title: Heterogeneous Effects of COVID-19 Lockdown Measures on Air Quality in Northern China
        date: 2020-11-11
       words: 5692
      flesch: 42
     summary: Section 5 presents the discussion on the implications of measures for air pollution control and Section 6 concludes this study. The economic cost will be huge if population mobility and industrial activities are unreasonably restricted, so it is important to establish appropriate, flexible, and sustainable measures for air pollution control.
    keywords: air; air pollution; air quality; control; control measures; covid-19; effect; measures; pollution; quality
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        item: #2680 of 7819
          id: cord-284829-dge21g0g
      author: Dinakaran, Damodharan
       title: Neuropsychiatric aspects of COVID-19 Pandemic: A Selective Review
        date: 2020-05-30
       words: 2291
      flesch: 30
     summary: Smell and taste disorders were reportedly more common in COVID-19 patients than in influenza (38). The Lancet Neurology Guillain Barre syndrome associated with COVID-19 infection: A case report Clinical characteristics of 113 deceased patients with coronavirus disease 2019:
    keywords: covid-19; infection; neuropsychiatric; patients; sars; study; syndrome
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        item: #2681 of 7819
          id: cord-284833-g914vww5
      author: Qiu, Tingting
       title: Chinese guidelines related to novel coronavirus pneumonia
        date: 2020-10-08
       words: 5738
      flesch: 39
     summary: With regards to TCM therapy for COVID-19 treatment, the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia recommended 5 TCM oral preparations during a medical observation period, 5 TCM injections for severe cases, and 7 TCM injections for critical cases. The objective of this manuscript is to identify and describe the pharmaceutical guidelines developed in China and to analyze adjustments in the treatment of COVID-19 over time based on the increasing experience in treating COVID-19 patients.
    keywords: cases; chloroquine; coronavirus; covid-19; diagnosis; guidelines; novel; patients; pneumonia; protocol; treatment
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        item: #2682 of 7819
          id: cord-284851-gtdyexp1
      author: Green, Jon
       title: Elusive consensus: Polarization in elite communication on the COVID-19 pandemic
        date: 2020-07-10
       words: 2791
      flesch: 38
     summary: From 17 January to 31 March, Democrats sent 19,803 tweets about COVID-19, while Republican members issued only 11,084 or 71 tweets per Democratic to 45 tweets per Republican member. The differential emphasis on the issue itself, independent of differences in word usage, suggests that Democratic members were sending earlier and stronger signals to their constituents that they should be concerned about the crisis.
    keywords: covid-19; members; polarization; public; republican; tweets
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        item: #2683 of 7819
          id: cord-284853-6efhdogi
      author: Xie, Yun
       title: Effect of regular intravenous immunoglobulin therapy on prognosis of severe pneumonia in patients with COVID-19
        date: 2020-04-10
       words: 1842
      flesch: 47
     summary: A brief perspective from the front line Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered,retrospective, observational study Hyperimmune IV Immunoglobulin Treatment: A Multicenter Double-Blind Randomized Controlled Trial for Patients With Severe Intravenous Immunoglobulin and Mortality in Pneumonia Patients With Septic Shock: An Observational Nationwide Study Immunoglobulin A Modulates Inflammatory Responses in an In Vitro Model of Pneumonia Efficacy of intravenous immunoglobulin in the prevention of pneumonia in patients with common variable immunodeficiency Systematic Review of Treatment Effects Current treatment options and the role of peptides as potential therapeutic components for Middle East Respiratory Syndrome (MERS): A review Intravenous Immunoglobulin Protects Against Severe Pandemic Influenza Infection Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Dose of IVIG B.Time of IVIG C. Hospital length of stay D. ICU length of stay We thank the hospital staff for their efforts in recruiting patients. Our study demonstrated that IVIG treatment in COVID-19 patients with severe pneumonia can improve the patients' indicators within a short time and improve the treatment efficiency of the patients with high effectiveness.
    keywords: covid-19; ivig; patients; pneumonia
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        item: #2684 of 7819
          id: cord-284873-m1ehdydr
      author: Cadegiani, Flavio A.
       title: Spironolactone: An Anti-androgenic and Anti-hypertensive Drug That May Provide Protection Against the Novel Coronavirus (SARS-CoV-2) Induced Acute Respiratory Distress Syndrome (ARDS) in COVID-19
        date: 2020-07-28
       words: 2544
      flesch: -8
     summary: Translational lessons from animal models Neurologic features in severe SARS-CoV-2 infection Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection Gastrointestinal manifestations of SARS-CoV-2 infection and virus load in fecal samples from a Hong Kong Cohort: systematic review and meta-analysis Evidence for gastrointestinal infection of SARS-CoV-2 Cutaneous manifestations in COVID-19: a first perspective COVID-19 and cutaneous manifestations Cardiovascular complications in patients with COVID-19: consequences of viral toxicities and host immune response COVID-19-related myocarditis in a 21-year-old female patient Cardiac and arrhythmic complications in patients with COVID-19 First case of COVID-19 complicated with fulminant myocarditis: a case report and insights Liver injury during highly pathogenic human coronavirus infections Gastrointestinal and liver manifestations in patients with COVID-19 Hepatic and gastrointestinal involvement in coronavirus disease Acute kidney injury in SARS-CoV-2 infected patients Acute renal impairment in coronavirus-associated severe acute respiratory syndrome Does COVID-19 affect male fertility? SARS-CoV-2 and the testis: similarity with other viruses and routes of infection Incidence of thrombotic complications in critically ill ICU patients with COVID-19 High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Hypercoagulability of COVID-19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Pulmonary embolism in patients with COVID-19: time to change the paradigm of computed tomography Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past Mineralocorticoid antagonists in ESRD: an overview of clinical trial evidence Non-genomic effects of spironolactone and eplerenone in cardiomyocytes of neonatal Wistar rats: do they evoke cardioprotective pathways? Pneumonia in Wuhan, China Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? China medical treatment expert group for Covid-19.
    keywords: ace2; angiotensin; cov-2; covid-19; patients; receptor; sars; spironolactone
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        item: #2685 of 7819
          id: cord-284879-sjkni2uc
      author: Song, Suk-Kyoon
       title: IgG Seroprevalence of COVID-19 among Individuals without a History of the Coronavirus Disease Infection in Daegu, Korea
        date: 2020-07-16
       words: 2564
      flesch: 45
     summary: Only 3.5% of study subjects reported the presence of confirmed COVID-19 cases among close contacts such as family, friends, or coworkers. 1 During an epidemic of infectious diseases, seroprevalence studies are important in demonstrating the widespread and undiagnosed infection in the general population.
    keywords: cases; covid-19; korea; number; seroprevalence; study
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        item: #2686 of 7819
          id: cord-284883-bkydu285
      author: Luis Silva, L.
       title: Brazil Health Care System preparation against COVID-19
        date: 2020-05-13
       words: 4501
      flesch: 46
     summary: To evaluate the geographical accessibility to emergency care service care was used the two-step floating catchment area (2SFCA) technique. Once the EII was computed, and the municipalities with high incidence within regions with low access to emergency care services care were identified, a Getis-Ord-Gi analysis was performed.
    keywords: beds; brazil; care; country; covid-19; emergency; health; icu; license; preprint; regions
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        item: #2687 of 7819
          id: cord-284888-bkee6isv
      author: Samies, Nicole L
       title: Rhabdomyolysis and Acute Renal Failure in an Adolescent With Coronavirus Disease 2019
        date: 2020-07-09
       words: 1462
      flesch: 41
     summary: Similar to our patient, all documented cases of COVID-19associated rhabdomyolysis occurred at or near time of presentation, suggesting rhabdomyolysis to be a finding in the acute setting of COVID-19. Urine output was restored following administration of intravenous fluids and diuretics, with close monitoring of renal function and CK levels.
    keywords: covid-19; level; patient; rhabdomyolysis
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        item: #2688 of 7819
          id: cord-284910-vjcrhwqz
      author: Kirresh, Ali
       title: COVID-19 infection and high intracoronary thrombus burden
        date: 2020-07-30
       words: 1774
      flesch: 28
     summary: Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China Chimeric antigen receptor T cells for sustained remissions in leukemia A Case of Coronavirus Disease 2019 With Concomitant Acute Cerebral Infarction and Deep Vein Thrombosis Cerebral Venous Sinus Thrombosis as a Presentation of COVID-19 Pulmonary Embolism in COVID-19 Patients: Awareness of an Increased Prevalence Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality Influenza and Cardiovascular Disease Is There a Causal Relationship? Coronary plaque instability in severe acute respiratory syndrome Review Article -High thrombus burden: a review of mechanisms and treatments Platelet adhesion and activation mechanisms in arterial thrombosis and ischaemic stroke Hypochlorous acid, a macrophage product, induces endothelial apoptosis and tissue factor expression: involvement of myeloperoxidase-mediated oxidant in plaque erosion and thrombogenesis Coagulopathy and Antiphospholipid Antibodies in Patients with COVID-19 Pathogenesis of antiphospholipid syndrome: understanding the antibodies Association of Treatment Dose Anticoagulation With In-Hospital Survival Among Hospitalized Patients With COVID-19 DOACs vs LMWHs in hospitalized medical patients: a systematic review and meta-analysis that informed 2018 ASH guidelines Platelet Inhibition With Cangrelor and Crushed Ticagrelor in Patients With ST-Segment-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention High rates of prasugrel and ticagrelor non-responder in patients treated with therapeutic hypothermia after cardiac arrest Impaired bioavailability and antiplatelet effect of high-dose clopidogrel in patients after cardiopulmonary resuscitation (CPR) Effect of cangrelor on periprocedural outcomes in percutaneous coronary interventions: a pooled analysis of patient-level data TCT-79 efficacy of cangrelor in lesions with high-risk and low-risk angiographic characteristics: the CHAMPION PHOENIX trial Poor survival with extracorporeal membrane oxygenation in acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19): Pooled analysis of early reports High thrombus burden in myocardial infarction is a real challenge and has an increased risk of no reflow, slow reflow, and distal embolization (16) .
    keywords: burden; covid-19; patients; risk; thrombosis; thrombus
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        item: #2689 of 7819
          id: cord-284925-vy2li9lz
      author: Lam, Dennis Shun Chiu
       title: COVID-19: Special Precautions in Ophthalmic Practice and FAQs on Personal Protection and Mask Selection
        date: 2020-04-29
       words: 4723
      flesch: 48
     summary: 37 Conjunctivitis was reported to be present in 0.8% to 5.2% of COVID-19 patients. Conjunctivitis could be present in COVID-19 patients, and virus may even be present in their tears and conjunctival secretion.
    keywords: air; coronavirus; covid-19; disease; infection; masks; n95; patients; respiratory; sars; transmission
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        item: #2690 of 7819
          id: cord-284944-hcgfe9wv
      author: Silvin, Aymeric
       title: Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19
        date: 2020-08-05
       words: 10810
      flesch: 35
     summary: Severe patients exhibited an expansion in the proportion of circulating neutrophils within the peripheral blood cell population (Figure 1E) , which was associated with an increase in their absolute number (Table S2) , as already reported . Focusing on neutrophil subsets, we noticed a slight increase in the fraction of CD10 Low CD101 + neutrophils in mild COVID-19 patients (Figure 1F) , whereas the fraction of CD10 Low CD101neutrophils was remarkably amplified in severe patients, suggesting an accumulation of immature subsets of neutrophils (Ng et al., 2019) in the peripheral blood of these patients ( Figure 1G and S1C-E).
    keywords: analysis; blood; calprotectin; cd14; cd16; cells; controls; covid-19; covid-19 patients; disease; et al; expression; figure; fraction; hla; levels; low; monocytes; neutrophils; patients; plasma
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        item: #2691 of 7819
          id: cord-284946-3y16j3ts
      author: Addo, Isaac Yeboah
       title: Double Pandemic: Racial Discrimination amid Corona virus Disease 2019
        date: 2020-10-20
       words: 5816
      flesch: 42
     summary: key: cord-284946-3y16j3ts authors: Addo, Isaac Yeboah title: Double Pandemic: Racial Discrimination amid Corona virus Disease 2019 date: 2020-10-20 journal: nan DOI: 10.1016/j.ssaho.2020.100074 sha: doc_id: 284946 cord_uid: 3y16j3ts The emergence of the COVID-19 pandemic has seen an escalation of racial discrimination against non-citizens and people of colour in many places around the world. Following that, the 2001 ground-breaking World Conference Against Racism, Racial Discrimination, Xenophobia, and Related Intolerance was held in Durban, South Africa to promote a global discussion on how to eliminate all forms of racial discrimination
    keywords: china; chinese; citizens; colour; covid-19; discrimination; non; pandemic; people; rights
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        item: #2692 of 7819
          id: cord-284948-zd27i5n6
      author: Pomar, María D. Ballesteros
       title: Nutricion Clínica en tiempos de COVID-19
        date: 2020-05-11
       words: 2060
      flesch: 28
     summary: Por ello, no se debe retrasar el inicio del tratamiento médico nutricional por el hecho de que el paciente tenga exceso de peso. La Sociedad Española de Endocrinología y Nutrición (SEEN) organizó desde el inicio de la pandemia, a través de su página web, un apartado específico de información sobre COVID-19 en el que se incluyeron recomendaciones específicas para el enriquecimiento de la dieta, prioritarias para estos pacientes con alto riesgo de DRE6.
    keywords: con; covid-19; han; las; los; nutricional; nutrición; pacientes; para; por; que; recomendaciones; tratamiento; una
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        item: #2693 of 7819
          id: cord-284955-6y6nnqno
      author: Jing Liang, Jing
       title: Characteristics of laboratory findings of COVID-19 patients with comorbid diabetes mellitus
        date: 2020-07-22
       words: 1832
      flesch: 54
     summary: The FPG was higher in patients with T2DM，but we did not observe a poorer control of FPG in COVID-19 patients with T2DM than in T2DM patients. However, in our study, UA levels were lower in COVID-19 patients and COVID-19 patients with T2DM than in T2DM patients; the levels of albumin showed a similar trend.
    keywords: covid-19; levels; patients
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        item: #2694 of 7819
          id: cord-284965-6hss53nu
      author: Evans, M. V.
       title: Reconciling model predictions with low reported cases of COVID-19 in Sub-Saharan Africa: Insights from Madagascar
        date: 2020-07-17
       words: 3093
      flesch: 45
     summary: We show that the current incidence of COVID-19 cases can be explained by any combination of the late introduction of first imported cases, early implementation of non-pharmaceutical interventions (NPIs), and low case detection rates. https://doi.org/10.1101/2020.07.15.20149195 doi: medRxiv preprint Our exercise shows that the current incidence of COVID-19 in Madagascar can be 145 explained by the early and effective implementation of NPIs and low case detection rates, both of 146 which are supported by strong anecdotal evidence.
    keywords: cases; covid-19; license; madagascar; preprint; ssa
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        item: #2695 of 7819
          id: cord-284979-lyt98od1
      author: Sia, Charmaine Si Min
       title: Critical Coronavirus Disease 2019 in a Hemodialysis Patient: A Proposed Clinical Management Strategy
        date: 2020-07-30
       words: 2863
      flesch: 40
     summary: So far, there are no specific studies using biomarkers to predict the risk of deterioration among COVID-19 ESKD patients, although ferritin and LDH have been found in many studies to be associated with severe illness and mortality in COVID-19 [4, 5] . During the previous 2003 SARS-CoV outbreak, dialysis patients were noted to have persistent viral shedding of up to 8 weeks [12] .
    keywords: case; covid-19; day; dialysis; disease; patients; pcr
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        item: #2696 of 7819
          id: cord-284983-xvtkso79
      author: Vigiola Cruz, Mariana
       title: Safety and Efficacy of Bedside Peritoneal Dialysis Catheter Placement in the COVID-19 Era: Initial Experience at a New York City Hospital
        date: 2020-05-26
       words: 3947
      flesch: 35
     summary: The controversy of placement of peritoneal dialysis catheters Comparison of early mechanical and infective complications in first time blind, bedside, midline percutaneous Tenckhoff Catheter insertion with ultra-short break-in period in diabetics and non-diabetics: setting new standards Infrastructure requirements for an urgent-start peritoneal dialysis program Urgent-start peritoneal dialysis: a chance for a new beginning Effect of prior abdominal surgery, peritonitis, and adhesions on catheter function and longterm outcome on peritoneal dialysis Operationalizing telehealth for home dialysis patients in the United States Minimizing the risk of COVID-19 among patients on dialysis On the frontline of the COVID-19 outbreak: keeping patients on long-term dialysis safe Acute renal failure in critically ill patients: a multinational, multicenter study COVID-19 and the inpatient dialysis unit: managing resources during contingency planning pre-crisis Acute kidney injury in critically Ill patients: a prospective randomized study of tidal peritoneal dialysis versus continuous renal replacement therapy Use of peritoneal dialysis in AKI: a systematic review Urgent-start dialysis: comparison of complications and outcomes between peritoneal dialysis and haemodialysis A global overview of the impact of peritoneal dialysis first or favored policies: an opinion Economic evaluation of urgent-start peritoneal dialysis versus urgent-start hemodialysis in the United States Critically Ill COVID-19 infected patients exhibit increased clot waveform analysis parameters consistent with hypercoagulability Hematological findings and complications of COVID-19 Randomized controlled trials for comparison of laparoscopic versus conventional open catheter placement in peritoneal dialysis patients: a meta-analysis What is the appropriate use of laparoscopy over open procedures in the current COVID-19 climate? Laparoscopy at all costs?
    keywords: bedside; catheter; covid-19; dialysis; icu; kidney; patients; placement; procedure
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        item: #2697 of 7819
          id: cord-284984-sdx3cceq
      author: Norman, Richard E.
       title: Typically Atypical: COVID‐19 Presenting as a Fall in an Older Adult
        date: 2020-05-14
       words: 709
      flesch: 48
     summary: Much of the attention regarding care of older adults with COVID-19 has focused on its significant mortality rate (reaching 10%-27% for those >85 years 6 ) or the possible need for rationing of limited resources, such as ventilators. Characterizing the spectrum of illness in older adults with COVID-19 will be important, however, to guide policies, support effective prognostication and decision making, and ensure equitable access to care.
    keywords: adults; coronavirus; covid-19
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        item: #2698 of 7819
          id: cord-284995-8lyr3gs4
      author: Fiorina, Laurent
       title: COVID-19 et troubles du rythme
        date: 2020-10-02
       words: 1416
      flesch: 46
     summary: L'embolie pulmonaire (EP) a été rapportée comme une complication fréquente de la COVID-19 présente jusqu'à 13.5% des patients admis en soins intensifs et ceci malgré une anticoagulation préventive standard [23] . Plus récemment une étude portant sur les IRM cardiaques réalisées à des patients convalescents (après un temps médian de 71 jours) a retrouvé des anomalies dans 78% des cas et des signes de processus inflammatoire myocardique encore en cours dans 60% des cas et ce indépendamment de la sévérité initiale de la maladie
    keywords: covid-19; dans; des; patients; troubles
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        item: #2699 of 7819
          id: cord-285030-ecsa83kf
      author: Jimenez-Cauhe, Juan
       title: Reply to “COVID-19 can present with a rash and be mistaken for Dengue”: Petechial rash in a patient with COVID-19 infection
        date: 2020-04-10
       words: 133
      flesch: 39
     summary: key: cord-285030-ecsa83kf authors: Jimenez-Cauhe, Juan; Ortega-Quijano, Daniel; Prieto-Barrios, Marta; Moreno-Arrones, Oscar M.; Fernandez-Nieto, Diego title: Reply to “COVID-19 can present with a rash and be mistaken for Dengue”: Petechial rash in a patient with COVID-19 infection date: 2020-04-10 journal: J Am Acad Dermatol DOI: 10.1016/j.jaad.2020.04.016 sha: doc_id: 285030 cord_uid: ecsa83kf nan Dermatologists have a unique opportunity to study COVID-19 cutaneous manifestations during this pandemic, and illustrative images are the first step for other colleagues to start looking for them. COVID-19 can present with a rash and be mistaken for Dengue Cutaneous manifestations in COVID-19: a first perspective
    keywords: covid-19
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        item: #2700 of 7819
          id: cord-285051-jmdfyydc
      author: Fan, Wen-juan
       title: Effect of advanced nursing care on psychological disorder in patients with COVID-19: A protocol of systematic review
        date: 2020-07-02
       words: 1568
      flesch: 48
     summary: Coronvirus pandemic Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis Prevalence and influencing factors of anxiety and depression symptoms in the first-line medical staff fighting against COVID-19 in Gansu Anxiety and depression among general population in China at the peak of the COVID-19 epidemic Clinical analysis of suspected COVID-19 patients with anxiety and depression Levels and predictors of anxiety, depression and health anxiety during COVID-19 pandemic in Turkish society: the importance of gender Stress, anxiety, and depression levels in the initial stage of the COVID-19 outbreak in a population sample in the northern Spain COVID-19 and depression Depression, dependence and prices of the COVID-19-Crisis Comparison of prevalence and associated factors of anxiety and depression among people affected by versus people unaffected by quarantine during the COVID-19 epidemic in Southwestern China Prevalence of self-reported depression and anxiety among pediatric medical staff members during the COVID-19 outbreak in Guiyang, China EDITORIAL: COVID-19 and Anxiety and Depression in Efficacy of internet-based integrated intervention on depression and anxiety symptoms in patients with COVID-19 Mental health status and intervention effects of cardiovascular nursing staff under the new coronavirus pneumonia epidemic Analysis of anxiety, depression level and influencing factors during isolation and observation of suspected patients with new coronavirus pneumonia Investigation on anxiety, depression and influencing factors of patients with new coronavirus pneumonia Anxiety and depression of elderly patients during the epidemic of new coronavirus pneumonia and its influencing factors The authors report no conflicts of interest. In addition, gray literatures will also be searched, including conference proceedings, reference lists of included studies, and websites of clinical trial registry.
    keywords: covid-19; patients; study
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        item: #2701 of 7819
          id: cord-285056-b2iltrqx
      author: Dichter, Martin N.
       title: COVID-19: it is time to balance infection management and person-centered care to maintain mental health of people living in German nursing homes
        date: 2020-05-12
       words: 2287
      flesch: 38
     summary: Although the validity of these early data must be questioned, it does indicate that nursing home residents are a particularly vulnerable group. Moreover, between 70% and 80% of nursing home residents are affected by dementia (Helvik et al., 2015; Rothgang, 2010) , a life-limiting disease requiring palliative care (van der Steen et al., 2014).
    keywords: care; covid-19; home; infection; nursing; people; residents
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        item: #2702 of 7819
          id: cord-285060-hzyf7w0k
      author: Cruz, Misael C.
       title: Adapting to the contemporary normal in cancer management and workflow during COVID-19 situation in the Philippines: Multi-cancer center collaborative approach
        date: 2020-06-13
       words: 1063
      flesch: 39
     summary: Patient with respiratory symptoms, with history of close contact to COVID-19 positive patients, and with travel history to areas with high incidence of COVID-19 were not allowed to enter the cancer center. Phase III shows the treatment management process for those with confirmed COVID-19, and those who will proceed with chemotherapy or radiation therapy.
    keywords: cancer; covid-19; management; pandemic; patient
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        item: #2703 of 7819
          id: cord-285069-duiowb88
      author: García-Pachón, Eduardo
       title: Asma y EPOC en pacientes hospitalizados por COVID-19
        date: 2020-05-31
       words: 1283
      flesch: 45
     summary: Además, podría sospecharse que la EPOC tiene mayor susceptibilidad a la infección por SARS-CoV-2 debido a que este virus utiliza como vía de entrada el receptor de la enzima convertidora de angiotensina II (ACE-2) Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan COVID-19 with different severity: A multi-center study of clinical features Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region Presenting Characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City Area Features of 16,749 hospitalized UK patients with COVID-19 using the ISARIC WHO Clinical Characterization Protocol Changing prevalence of current asthma and inhaled corticosteroid treatment in the UK: population-based cohort 2006-2016 Cambios en la prevalencia de asma en la población española del Estudio de Salud Respiratoria de la Comunidad Europea (ECRHS-II)
    keywords: asma; con; epoc; los; pacientes; por; que
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        item: #2704 of 7819
          id: cord-285103-lj2vmbik
      author: Louie, Philip K.
       title: The Impact of COVID-19 Pandemic on Spine Surgeons Worldwide
        date: 2020-05-06
       words: 3621
      flesch: 43
     summary: 94.7% expressed a need for formal, international guidelines to manage COVID-19 patients. International and governmental recommendations have curbed nonemergent surgery in order to optimize delivering care to COVID-19 patients.
    keywords: care; covid-19; health; impact; respondents; surgeons; survey; testing
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        item: #2705 of 7819
          id: cord-285111-qjclp51i
      author: Davanzo, Riccardo
       title: Breastfeeding and coronavirus disease‐2019: Ad interim indications of the Italian Society of Neonatology endorsed by the Union of European Neonatal & Perinatal Societies
        date: 2020-04-26
       words: 3625
      flesch: 42
     summary: In the light of current available scientific data and the protective potential of breast milk, a woman with suspected or confirmed The hospital management of mothers suspected of or with confirmed COVID-19 must foresee two options: rooming-in or separation between mother and neonate. A recent paper from JAMA Pediatrics reports that among 33neonates of COVID-19 mothers, three presented respiratory symptoms in the first days of life and tested positive for COVID-19 on Day 2after childbirth (Zeng, Xia, & Yuan, 2020) .
    keywords: breastfeeding; coronavirus; cov-2; covid-19; infection; mother; neonate; sars
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        item: #2706 of 7819
          id: cord-285187-1h5tjs0r
      author: Kuchenbuch, Mathieu
       title: An accelerated shift in the use of remote systems in epilepsy due to the COVID-19 pandemic
        date: 2020-08-31
       words: 4828
      flesch: 47
     summary: key: cord-285187-1h5tjs0r authors: Kuchenbuch, Mathieu; d’Onofrio, Gianluca; Wirrell, Elaine; Jiang, Yuwu; Dupont, Sophie; Grinspan, Zachary M.; Auvin, Stephane; Wilmshurst, Jo M.; Arzimanoglou, Alexis; Cross, J. Helen; Specchio, Nicola; Nabbout, Rima title: An accelerated shift in the use of remote systems in epilepsy due to the COVID-19 pandemic date: 2020-08-31 journal: Epilepsy Behav DOI: 10.1016/j.yebeh.2020.107376 sha: doc_id: 285187 cord_uid: 1h5tjs0r PURPOSE: The purpose of the study was to describe epileptologists' opinion on the increased use of remote systems implemented during the COVID-19 pandemic across clinics, education, and scientific meetings activities.
    keywords: china; covid-19; epilepsy; face; france; italy; pandemic; remote; respondents; systems
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        item: #2707 of 7819
          id: cord-285202-aiap6z9u
      author: Short, Briana
       title: Rapid implementation of a mobile prone team during the COVID-19 pandemic
        date: 2020-08-25
       words: 1728
      flesch: 40
     summary: The rapid development of a mobile prone team safely provided prone positioning to a large number of COVID-19 patients with moderate-to-severe ARDS. During the COVID-19 pandemic, the rapid development and implementation of a mobile prone team allowed for increased capacity to prone patients with moderate-to-severe ARDS in ICUs beyond the MICUs to meet the surge of critically ill patients during the height of the pandemic.
    keywords: ards; covid-19; patients; positioning; team
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        item: #2708 of 7819
          id: cord-285207-hsbzcpl3
      author: Facchin, Federico
       title: COVID-19: Initial experience of hand surgeons in Northern Italy
        date: 2020-05-04
       words: 579
      flesch: 53
     summary: We agree that hand surgery units need to share COVID-19 preventive protocols to allow elective and non-elective procedures to continue safely. Given their role in such important period, hand surgery units should share their protocols and their know-how to develop an international consensus in face of the current pandemic.
    keywords: covid-19; hand
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        item: #2709 of 7819
          id: cord-285223-07o9irev
      author: Malik, Usman Rashid
       title: Knowledge, Attitude, and Practices of Healthcare Professionals on COVID-19 and Risk Assessment to Prevent the Epidemic Spread: A Multicenter Cross-Sectional Study from Punjab, Pakistan
        date: 2020-09-02
       words: 4803
      flesch: 47
     summary: Deaths of healthcare professionals as a result of exposure to COVID-19 patients have been reported in countries including the USA, the UK, China, and Italy The clinical symptoms most commonly observed in COVID-19 patients in a recent study were fever, cough, fatigue, or myalgia and dyspnea
    keywords: attitude; covid-19; disease; healthcare; knowledge; participants; practices; professionals; risk
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        item: #2710 of 7819
          id: cord-285228-famhbr16
      author: Larsen, Joseph R.
       title: Modeling the Onset of Symptoms of COVID-19
        date: 2020-08-13
       words: 7015
      flesch: 46
     summary: The most likely path of COVID-19 symptoms is fever, then cough, and next either sore throat, myalgia, or headache, followed by nausea/vomiting, and finally diarrhea, and this order is the same as the one indicated by the implementation developed from the confirmation dataset (COVID-19 with N = 1,099) (Figure 4) (16) . In addition, datasets that contain information of symptom order and strains of COVID-19 allow for further studies that may determine whether onset of symptoms vary in specific strains (32) , and whether risk factors, such as obesity (33) , and environmental factors, such as temperature (34) affect symptom order.
    keywords: cough; covid-19; diarrhea; fever; influenza; order; path; patients; symptoms
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        item: #2711 of 7819
          id: cord-285232-0p27ez9i
      author: Boriani, Giuseppe
       title: Impact of COVID-19 pandemic on the clinical activities related to arrhythmias and electrophysiology in Italy: results of a survey promoted by AIAC (Italian Association of Arrhythmology and Cardiac Pacing)
        date: 2020-09-05
       words: 5857
      flesch: 29
     summary: A randomized trial in primary care HRS/EHRA/ APHRS/LAHRS/ACC/AHA worldwide practice update for telehealth and arrhythmia monitoring during and after a pandemic Management of atrial fibrillation in the emergency room and in the cardiology ward: the BLITZ AF study The epidemiological burden of atrial fibrillation: a challenge for clinicians and health care systems Direct oral anticoagulants vs non-vitamin K antagonist in atrial fibrillation: a prospective, propensity score adjusted cohort study Changes to oral anticoagulant therapy and risk of death over a 3-year followup of a contemporary cohort of European patients with atrial fibrillation final report of the EURObservational Research Programme on Atrial Fibrillation (EORP-AF) pilot general registry Increased burden of comorbidities and risk of cardiovascular death in atrial fibrillation patients in Europe over ten years: a comparison between EORP-AF pilot and EHS-AF registries Atrial fibrillation and prediction of mortality by conventional clinical score systems according to the setting of care The Euro Heart Survey and EURObservational Research Programme (EORP) in atrial fibrillation registries: contribution to epidemiology, clinical management and therapy of atrial fibrillation patients over the last 20 years Long-term relationship between atrial fibrillation, multimorbidity and oral anticoagulant drug use Association between antithrombotic treatment and outcomes at 1-year follow-up in patients with atrial fibrillation: the EORP-AF General Long-Term Registry Syncope in the German Nationwide inpatient sample-syncope in atrial fibrillation/flutter is related to pulmonary embolism and is accompanied by higher in-hospital mortality Effects of remote monitoring of cardiac implantable electronic devices after stroke or transient ischemic attack Occurrence of atrial fibrillation in pacemaker patients and its association with sleep apnea and heart rate variability Nationwide survey on the current practice of ventricular tachycardia ablation Clinical and organizational management of cardiac implantable electronic device replacements: an Italian Survey promoted by AIAC (Italian Association of Arrhythmology and Cardiac Pacing) The vast majority of participating centres (95.2%) reported a significant reduction in the number of elective pacemaker implantations during the outbreak period compared to the corresponding two months of year 2019 (50.0% of centres reported a reduction of > 50%).
    keywords: cardiac; care; centres; covid-19; elective; italian; number; pandemic; patients; procedures; reduction; survey
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        item: #2712 of 7819
          id: cord-285254-8a1cia8s
      author: Parry, Nicola M.A.
       title: COVID-19 and pets: When pandemic meets panic
        date: 2020-12-31
       words: 3632
      flesch: 52
     summary: The Hong Kong Society for the Prevention of Cruelty to Animals issued a statement to inform the public that there is no evidence to show that pets can transmit the virus to people, and warning people against compromising animal welfare [5] . [4] The animal welfare impact And while the pandemic has resulted in devastating consequences for health systems and economic stability throughout the world, it has also had undesirable, but perhaps not surprising, ramifications for animal welfare.
    keywords: animal; coronavirus; cov-2; covid-19; health; pets; sars
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        item: #2713 of 7819
          id: cord-285277-8w03car3
      author: Hare, Nathan
       title: COVID-19: Unmasking Telemedicine.
        date: 2020-06-27
       words: 6012
      flesch: 49
     summary: While Medicare only covered telemedicine services for established 337 patients, some private payers permitted telemedicine visits for new patients, but not with the 338 standard new patient CPT codes. 3 100 This rapid need for telemedicine visits has generated the demand to effectively educate 101 allergists/immunologists on how to optimize utilization.
    keywords: allergy; care; coverage; covid-19; health; patient; person; reimbursement; services; state; telemedicine; time; visit
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        item: #2714 of 7819
          id: cord-285291-pep4opiq
      author: Remy, Kenneth E.
       title: Caring for Critically Ill Adults With Coronavirus Disease 2019 in a PICU: Recommendations by Dual Trained Intensivists*
        date: 2020-04-29
       words: 7169
      flesch: 29
     summary: Part 2: Treatment Antithrombotic therapy for VTE disease: CHEST guideline and expert panel report Treatment of acute pulmonary embolism: Update on newer pharmacologic and interventional strategies guidelines for management of venous thromboembolism: Prophylaxis for hospitalized and nonhospitalized medical patients Clinical Guidelines Committee of the American College of Physicians: Venous thromboembolism prophylaxis in hospitalized patients: A clinical practice guideline from the American College of Physicians Diagnosis of gastrointestinal bleeding: A practical guide for clinicians PEPTIC Investigators for the Australian and New Zealand Intensive Care Society Clinical Trials Group, Alberta Health Services Critical Care Strategic Clinical Network, and the Irish Critical Care Trials Group: Effect of stress ulcer prophylaxis with proton pump inhibitors vs histamine-2 receptor blockers on in-hospital mortality among ICU patients receiving invasive mechanical ventilation: The PEPTIC randomized clinical trial Hyperglycemic crises in adult patients with diabetes Hyperosmolar hyperglycemic state: A historic review of the clinical presentation, diagnosis, and treatment Acute kidney injury enhances outcome prediction ability of sequential organ failure assessment score in critically ill patients Acute renal impairment in coronavirus-associated severe acute respiratory syndrome SMART Investigators and the Pragmatic Critical Care Research Group: Balanced crystalloids versus saline in critically ill adults Delirium in the critically ill patient Clinical practice guidelines for the prevention and management of pain, agitation/sedation, delirium, immobility, and sleep disruption in adult patients in the ICU ICU delirium -a diagnostic and therapeutic challenge in the intensive care unit Sedation and delirium in the intensive care unit Incidence and prevalence of pressure injuries in adult intensive care patients: A systematic review and meta-analysis Risk factors for pressure injury development in critically ill patients in the intensive care unit: A systematic review protocol ICU-acquired weakness and recovery from critical illness Critical illness polyneuropathy and myopathy: A major cause of muscle weakness and paralysis Critical illness myopathy and neuropathy Pressure injury risk factors in adult critical care patients: A review of the literature Effectiveness of pressure ulcer prevention strategies for adult patients in intensive care units: A systematic review Treatment of pressure ulcers: A systematic review Management of acute alcohol withdrawal syndrome in critically ill patients Approach to the complicated alcohol withdrawal patient The use of dexmedetomidine as an adjuvant to benzodiazepine-based therapy to decrease the severity of delirium in alcohol withdrawal in adult intensive care unit patients: A systematic review Proxy decision making for incompetent patients. Acute decompensated heart failure (ADHF) is one of the main causes of respiratory distress in adult patients requiring the ICU (99) .
    keywords: acute; adults; care; covid-19; disease; distress; failure; heart; icu; management; mortality; patients; pressure; sedation; syndrome; treatment; trial; use; ventilation
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        item: #2715 of 7819
          id: cord-285315-7r44j3q9
      author: Bein, Berthold
       title: SARS-CoV-2/COVID-19: Empfehlungen zu Diagnostik und Therapie
        date: 2020-04-09
       words: 2255
      flesch: 41
     summary: Angesteckten pro Infizierten über der von SARS. Intensive Care Med Empfehlungen zur intensivmedizinischen Therapie von Patienten mit COVID-19 Extravascular lung water predicts progression to acute lung injury in patients with increased risk Best practice & research clinical anaesthesiology:
    keywords: bei; china; clinical; coronavirus; cov-2; covid-19; das; der; die; eine; mit; patienten; patients; sars; sich; und; von; werden
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        item: #2716 of 7819
          id: cord-285327-m0yaa1oa
      author: Vuitton, Dominique A.
       title: A plea for the pathogenic role of immune complexes in severe Covid-19
        date: 2020-06-08
       words: 676
      flesch: 22
     summary: Historical studies on serum sickness focused on the circumstances of IC disease occurrence and stressed the triggering effect of differences in hydrostatic pressure and vasoactive changes in microvessels to enhance IC deposit, inflammatory reaction, endothelitis and microthrombosis Therapy with plasma from Covid-19 patients after recovery could, in addition to The specific humoral and cellular immune response towards SARS-CoV2 was comprehensively analyzed in a non-severe case of the disease [11] .
    keywords: covid-19; cytokine; immune
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        item: #2717 of 7819
          id: cord-285349-850n4pot
      author: Omarjee, Loukman
       title: Can Ticagrelor be used to prevent sepsis-induced coagulopathy in COVID-19?
        date: 2020-05-21
       words: 1369
      flesch: 36
     summary: In the PLATelet inhibition and patient Outcomes (PLATO) study, Ticagrelor reduced mortality risk following pulmonary adverse events such as bacterial kung infection and sepsis in acute coronary syndrome patients [7] . This was demonstrated in the XANTHIPPE study, since Ticagrelor use was safe with no major J o u r n a l P r e -p r o o f Journal Pre-proof bleeding reported [9] .
    keywords: covid-19; mortality; platelet; sepsis; ticagrelor
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        item: #2718 of 7819
          id: cord-285360-svczr721
      author: Ganesh, Aravind
       title: Ignorance is not bliss: managing uncertainty in acute stroke treatment in the COVID-19 era
        date: 2020-10-31
       words: 1609
      flesch: 25
     summary: Recognizing the added risks of treatment delays or misses in these times, we may adopt a lower threshold for direct-to-mothership paradigms that bring stroke patients directly to comprehensive stroke centers to minimize blind spots. Prehospital triage of acute stroke patients during the COVID-19 pandemic Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
    keywords: covid-19; information; pandemic; patient; stroke; treatment
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        item: #2719 of 7819
          id: cord-285369-ktg2b9jb
      author: Mohamed, Mouhand F. H.
       title: Frequency of Abnormalities Detected by Point-of-Care Lung Ultrasound in Symptomatic COVID-19 Patients: Systematic Review and Meta-Analysis
        date: 2020-06-02
       words: 3225
      flesch: 46
     summary: Recent data suggested the utility of lung ultrasound (LUS) in the diagnosis of COVID-19 by detecting an interstitial pattern (B-pattern). The pooled proportion (PP) of B-pattern detected by lung ultrasound (US) was 0.97 (95% CI: 0.94–1.00 I(2) 0%, Q 4.6).
    keywords: covid-19; frequency; lung; patients; studies; ultrasound
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        item: #2720 of 7819
          id: cord-285370-qv64xzjh
      author: Dandel, Michael
       title: Cardiac manifestations of COVID-19 infection: the role of echocardiography in patient management
        date: 2020-08-24
       words: 1889
      flesch: 34
     summary: The 2D-ECHO-derived ejection fraction (EF) for assessment of RV function is not any more recommended because the complex RV shape with poor definition of its endocardial surface and the limited imaging windows make the EF measurements less reliable. Tissue Doppler imaging (TDI) derived lateral tricuspid annulus peak systolic velocity (TAPS') is also useful for evaluation of RV function.
    keywords: covid-19; function; patients; pressure
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        item: #2721 of 7819
          id: cord-285384-xay5aw7y
      author: Naser, A. Y.
       title: Mental health status of the general population, healthcare professionals, and university students during 2019 coronavirus disease outbreak in Jordan: a cross-sectional study
        date: 2020-04-11
       words: 4199
      flesch: 47
     summary: University students, females, younger population (18-29 years), single and divorced, participants who completed their bachelor degree (from the GP), with lower-income category (500 JD and below), pulmonologist and ENT specialists (for HCPs), participants with no history of chronic diseases (for the GP and USs) tend to have higher depression and anxiety median scores compared to others. The above-mentioned remarks may explain the surprising conclusion that USs are more affected and have higher depression and anxiety rates compared to HCPs who are in the centre of the risk and seriously affected by this pandemic disease.
    keywords: anxiety; covid-19; depression; hcps; license; participants; preprint; risk; study
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        item: #2722 of 7819
          id: cord-285395-vybruu3o
      author: Polat, Veli
       title: Sudden death due to acute pulmonary embolism in a young woman with COVID-19
        date: 2020-05-11
       words: 1115
      flesch: 34
     summary: COVID-19 infection appears to induce venous thromboembolism, especially pulmonary embolism. A few cases and trials of acute PE associated with COVID-19 infection have recently been reported [2, 3, 5, 10].
    keywords: acute; covid-19; infection
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        item: #2723 of 7819
          id: cord-285397-rc65rv6r
      author: Comfort, Louise
       title: Crisis Decision Making on a Global Scale: Transition from Cognition to Collective Action under Threat of COVID‐19
        date: 2020-05-30
       words: 3819
      flesch: 44
     summary: Bold redesign of existing international organizations -WHO, OCHA, and UNDRRthat monitor and compare the status of global risk would reinforce cognition in facilitating effective crisis response across the globe by partnering with nations to work with their local communities. Consequently, the mechanisms for credible search and exchange of valid information to inform decisions and action on multiple scales of operation at the level and speed needed to inform global decision making were limited, leaving nations to chart individual courses of action with widely varying results.
    keywords: capacity; cognition; communication; covid-19; health; level; public; response; risk
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        item: #2724 of 7819
          id: cord-285402-x86yw525
      author: Banskota, Swechya
       title: 15 Smartphone Apps for Older Adults to Use While in Isolation During the COVID-19 Pandemic
        date: 2020-04-14
       words: 5255
      flesch: 49
     summary: We conducted a literature review using PubMed and Google Scholar on the topic, but as many apps are not rigorously tested for usability and efficacy in the OA population, this selection was mainly based on expert review. Many apps are available to help OAs navigate isolation during the COVID-19 pandemic.
    keywords: access; adults; apps; care; covid-19; health; isolation; medical; medication; oas; telehealth; telemedicine; use
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        item: #2725 of 7819
          id: cord-285406-mlpqvshk
      author: Van Praet, Jens T.
       title: Prevention of nosocomial COVID-19: Another challenge of the pandemic
        date: 2020-04-23
       words: 681
      flesch: 42
     summary: In these same weeks, the screening positivity rates of symptomatic healthcare workers in our hospital were 8.6% (6 out of 70), 31% (17 out of 54), 39% (16 out of 41) and 28% (16 out of 57), respectively and the numbers of patients diagnosed with probable nosocomial COVID-19 were 0, 4, 4, and 23, respectively. We defined probable nosocomial COVID-19 as a diagnosis made beyond 4 days of hospitalization and the absence of clinical suspicion of COVID-19 upon admission.
    keywords: covid-19; week
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        item: #2726 of 7819
          id: cord-285407-h9og17i9
      author: Annunziata, Salvatore
       title: Surveys on COVID-19 in nuclear medicine: what happened and what we learned
        date: 2020-09-24
       words: 1136
      flesch: 42
     summary: All studies agreed that COVID-19 had a relevant impact on NM departments. For these reasons, some research groups promoted different international surveys to understand the impact of the pandemic on NM departments
    keywords: covid-19; departments
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        item: #2727 of 7819
          id: cord-285414-vd2d7db2
      author: Yu, Qian
       title: Multicenter cohort study demonstrates more consolidation in upper lungs on initial CT increases the risk of adverse clinical outcome in COVID-19 patients
        date: 2020-04-27
       words: 3087
      flesch: 44
     summary: This finding is of significant clinical implications, not only in providing us a simpler way to identify high risk patients on CT, but also has potential to extend to chest radiographs, where upper lobe consolidations are easy to be perceived. The finding provided us a simpler way to identify high risk patients on CT that the elder with large consolidation in upper lungs should be paid more attention during the treatment of COVID-19.
    keywords: admission; clinical; covid-19; endpoints; patients; study
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        item: #2728 of 7819
          id: cord-285428-fcrunf38
      author: Halstead, Scott B.
       title: COVID-19: The Need for Immunoprevention at Industrial Scale
        date: 2020-04-08
       words: 685
      flesch: 40
     summary: Efforts are well underway by many groups to derive monoclonal antibodies or manufacture gamma globulin from the huge cohort of COVID-19 convalescent immunes. [7] [8] In the 1950s, William McD Hammon at the University of Pittsburgh demonstrated that gamma globulin given to 100,000 children in a blinded efficacy trial successfully blunted paralysis attack rates during epidemics of poliomyelitis.
    keywords: antibodies; covid-19; gamma
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        item: #2729 of 7819
          id: cord-285435-fu90vb2z
      author: Björklund, Tua A.
       title: Expanding entrepreneurial solution spaces in times of crisis: Business model experimentation amongst packaged food and beverage ventures
        date: 2020-11-30
       words: 6819
      flesch: 27
     summary: Both the social media analysis and founder interviews showcased an abundance of new business model experiments in response to the Covid-19 pandemic amongst Finnish packaged food and beverage ventures. key: cord-285435-fu90vb2z authors: Björklund, Tua A.; Mikkonen, Maria; Mattila, Pauliina; van der Marel, Floris title: Expanding entrepreneurial solution spaces in times of crisis: Business model experimentation amongst packaged food and beverage ventures date: 2020-11-30 journal: Journal of Business Venturing Insights DOI: 10.1016/j.jbvi.2020.e00197 sha: doc_id: 285435 cord_uid: fu90vb2z Research summary Times of crisis require entrepreneurial responses to mitigate adverse effects and address new opportunities.
    keywords: action; business; capabilities; creation; crisis; entrepreneurs; et al; experimentation; experiments; model; solution; value; ventures
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        item: #2730 of 7819
          id: cord-285467-uxfk6k3c
      author: Ragni, Enrico
       title: Management of osteoarthritis during COVID‐19 pandemic
        date: 2020-05-21
       words: 7081
      flesch: 25
     summary: OA patients often show a large array of concomitant pathologies such as diabetes, inflammation and cardiovascular diseases that are again shared with COVID‐19 patients and may therefore increase complications. Predisposing comorbidities in OA patients At the moment, no studies have investigated a potential relationship between respiratory viral infections and the development of OA, as described for parainfluenza and coronavirus and the incidence of rheumatoid arthritis (30) .
    keywords: article; copyright; covid-19; disease; drugs; infection; nsaids; opioids; osteoarthritis; patients; pneumonia; rights; risk; sars; treatment; use
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        item: #2731 of 7819
          id: cord-285469-b61y9ezi
      author: Hernández-Fernández, Francisco
       title: Cerebrovascular disease in patients with COVID-19: neuroimaging, histological and clinical description
        date: 2020-07-09
       words: 7016
      flesch: 37
     summary: Although our observed incidence of CVD in COVID-19 patients is slightly lower than reported (Mao et al., 2020) , deferred medical care, and the lower number of patients admitted with lacunar infarctions could have underestimated the actual incidence of CVD. Bivariates studies were designed to contrast the main variables among CVD patients, between ischaemic/haemorrhagic subtypes within the COVID-19 group, and to assess clinical prognosis.
    keywords: brain; cases; cerebral; cov-2; covid-19; cvd; et al; findings; infection; patients; sars; stroke; study
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        item: #2732 of 7819
          id: cord-285472-cj5r3xt1
      author: Kaur, Parminder
       title: Acute upper limb ischemia in a patient with COVID-19
        date: 2020-05-13
       words: 1119
      flesch: 33
     summary: WHO Director-General's remarks at the media briefing on 2019-nCoV on 11 Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China Changes in blood coagulation in patients with severe coronavirus disease 2019 (COVID-19): a meta-analysis Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19 Complement activation contributes to severe acute respiratory syndrome coronavirus pathogenesis Blockade of the C5a-C5aR axis alleviates lung damage in hDPP4-transgenic mice infected with MERS-CoV Will complement inhibition be the new target in treating COVID-19 related systemic thrombosis? The prevalence of thrombosis among patients with COVID-19 is not fully established as most of the literature focus on hospitalized patients who are more likely to have comorbid conditions than individuals with asymptomatic or mild disease burden.
    keywords: coronavirus; covid-19; disease; patients
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        item: #2733 of 7819
          id: cord-285484-owpnhplk
      author: Salfi, F.
       title: Changes of evening exposure to electronic devices during the COVID-19 lockdown affect the time course of sleep disturbances
        date: 2020-10-21
       words: 3942
      flesch: 43
     summary: Additionally, from the PSQI questionnaire, we extracted other variables such as total sleep time (TST, min), sleep onset latency (SOL, min), bedtime (BT, hh:mm), and rise time (RT, hh:mm). Conversely, other studies showed protective effects of blocking blue light emissions on melatonin regulation 31 and sleep quality, both in healthy 32 and clinical insomniac subjects.
    keywords: exposure; light; medrxiv; preprint; review; screen; sleep; time
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        item: #2734 of 7819
          id: cord-285486-99trkti1
      author: Abd-Elsalam, Sherief
       title: Hydroxychloroquine in the Treatment of COVID-19: A Multicenter Randomized Controlled Study
        date: 2020-08-14
       words: 2929
      flesch: 47
     summary: Univariate logistic regression analysis showed that HCQ treatment was not significantly associated with decreased mortality in COVID-19 patients. Diagnosis and Treatment Protocol for COVID-19 G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences Chloroquine or hydroxychloroquine for prophylaxis of COVID-19 Hydroxychloroquine for COVID-19: what is our current state of knowledge? Characteristics, treatment outcomes and role of hydroxychloroquine among 522 COVID-19 hospitalized patients in Jaipur city: an epidemio-clinical study Observational study of hydroxychloroquine in hospitalized patients with COVID-19 COVID-19 coronavirus research has overall low methodological quality thus far: case in point for chloroquine/hydroxychloroquine Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial Virological and clinical cure in COVID-19 patients treated with hydroxychloroquine: a systematic review and meta-analysis Effect of hydroxychloroquine in hospitalized patients with COVID-19: preliminary results from a multi-centre, randomized A randomized trial of hydroxychloroquine as postexposure prophylaxis for COVID-19 Hydroxychloroquine as postexposure prophylaxis for COVID-19 SARS-CoV-2: the path of prevention and control APASL COVID Task Force, APASL COVID Liver Injury Spectrum Study, 2020.
    keywords: care; covid-19; group; hcq; hydroxychloroquine; patients; treatment
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        item: #2735 of 7819
          id: cord-285490-tpsf05ca
      author: Solís, José Gabriel
       title: Case Report: Rhabdomyolysis in a Patient with COVID-19: A Proposed Diagnostic-Therapeutic Algorithm
        date: 2020-07-29
       words: 1796
      flesch: 33
     summary: We recommend measuring CK levels in COVID-19 patients with suggestive clinical or analytical alterations, especially in those with AKI, in which it can be a pathophysiological mechanism that requires early and aggressive treatment to prevent chronic kidney damage or death. The diagnosis of COVID-19 and severe rhabdomyolysis complicated with AKI was made.
    keywords: acute; covid-19; muscle; patients; rhabdomyolysis; sars
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        item: #2736 of 7819
          id: cord-285491-ad6jiqh9
      author: Lazzerini, Marzia
       title: Delayed access or provision of care in Italy resulting from fear of COVID-19
        date: 2020-04-09
       words: 1190
      flesch: 47
     summary: Within an Italian Pediatric Hospital Research Network, 12 cases of delayed access to hospital care have been reported during the week March 23-27 across five hospitals (three third-level referral hospitals and two second-level hospitals; figure) . Two children presented to the emergency department with acuteonset type 1 diabetes and severe ketoacidosis due to delayed access to hospital care, even though parents had recognised abnormal symptoms (eg, polydipsia, polyuria, and dyspnoea); both required admission to the intensive care unit (ICU).
    keywords: care; covid-19; health; hospital
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        item: #2737 of 7819
          id: cord-285502-rvv64190
      author: Yang, Lie
       title: Emergency response to the explosive growth of health care wastes during COVID-19 pandemic in Wuhan, China
        date: 2020-08-18
       words: 4133
      flesch: 39
     summary: In the first stage, the operation loading rate of HCWs treatment facility was 93.71%, which was quite close to full loading operation conditions of treatment facilities. The amount of the stored but untreated HCWs is demonstrated in The high-load period of the residual stored amount is mainly within the second stage of HCWs treatment.
    keywords: covid-19; facilities; hcws; hospitals; management; treatment; waste; wuhan
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        item: #2738 of 7819
          id: cord-285510-qrivd52o
      author: Zokaeinikoo, M.
       title: AIDCOV: An Interpretable Artificial Intelligence Model for Detection of COVID-19 from Chest Radiography Images
        date: 2020-05-25
       words: 4640
      flesch: 46
     summary: We develop a novel hierarchical attention neural network model to classify chest radiography images as belonging to a person with either COVID-19, other infections, or no pneumonia (i.e., normal). AIDCOV has a sensitivity of 99.3%, a specificity of 99.98%, and a positive predictive value of 99.6% in detecting COVID-19 from chest radiography images.
    keywords: attention; chest; covid-19; images; model; radiography
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        item: #2739 of 7819
          id: cord-285513-pkqos0s5
      author: Stangvaltaite-Mouhat, Lina
       title: Dental Health Services Response to COVID-19 in Norway
        date: 2020-08-12
       words: 5749
      flesch: 41
     summary: Regarding perceptions, dental staff was asked on a 5-point Likert scale (1_completely agree, 5_completely disagree) to assess four statements: dental staff risk to be infected; if workplace had adequate infection control equipment; how workplace handled the current situation; if workplace was well equipped to handle an escalation. key: cord-285513-pkqos0s5 authors: Stangvaltaite-Mouhat, Lina; Uhlen, Marte-Mari; Skudutyte-Rysstad, Rasa; Szyszko Hovden, Ewa Alicja; Shabestari, Maziar; Ansteinsson, Vibeke Elise title: Dental Health Services Response to COVID-19 in Norway date: 2020-08-12 journal: Int J Environ Res Public Health DOI: 10.3390/ijerph17165843 sha: doc_id: 285513 cord_uid: pkqos0s5 We aimed to investigate the management of urgent dental care, the perception of risk and workplace preparedness among dental staff in Norway during the COVID-19 pandemic.
    keywords: clinics; control; covid-19; dental; health; infection; patients; staff; study
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        item: #2740 of 7819
          id: cord-285521-lvzdmtun
      author: Olagundoye, Olawunmi
       title: Recommendations for a national Coronavirus disease 2019 response guideline for the care of older persons in Nigeria during and post-pandemic: A family physician’s perspective
        date: 2020-08-11
       words: 1652
      flesch: 44
     summary: key: cord-285521-lvzdmtun authors: Olagundoye, Olawunmi; Enema, Oluwayemisi; Adebowale, Adunola title: Recommendations for a national Coronavirus disease 2019 response guideline for the care of older persons in Nigeria during and post-pandemic: A family physician’s perspective date: 2020-08-11 journal: Based on currently available information, older persons and people of any age who have serious underlying medical conditions may be at higher risk of severe illness from COVID-19.
    keywords: care; covid-19; health; persons
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        item: #2741 of 7819
          id: cord-285526-xm9yj5ua
      author: Gill, Balvinder Singh
       title: Modelling the Effectiveness of Epidemic Control Measures in Preventing the Transmission of COVID-19 in Malaysia
        date: 2020-07-30
       words: 4342
      flesch: 44
     summary: MCO measures reduce the peak number of active COVID-19 cases by 99.1% and reduce (ζ) from 25 (pre-MCO) to 7 (during MCO). In addition, the findings from our study showed that MCO measures would reduce the peak number of active COVID-19 cases by 99.1% compared to the pre-MCO model simulation, where no MCO measures were taken.
    keywords: cases; control; covid-19; malaysia; mco; measures; model; outbreak
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        item: #2742 of 7819
          id: cord-285533-f1fonmo6
      author: Zeng, Jia
       title: Clinical efficacy of tocilizumab treatment in severe and critical COVID-19 patients
        date: 2020-09-06
       words: 2888
      flesch: 38
     summary: Tocilizumab treatment is effective against IL-6 in COVID-19 patients, but it does not completely inhibit the inflammation and cytokine storm in all patients with COVID-19.In the clinical treatment of COVID-19 patients, attention should be paid to the timing of drug administration and other adjuvant treatments. These findings showed that the cytokine storm and inflammation in COVID-19 patients can be controlled by tocilizumab treatment.
    keywords: covid-19; cytokine; il-6; patients; tocilizumab; treatment
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        item: #2743 of 7819
          id: cord-285574-i0dh1u5i
      author: Ferini-Strambi, Luigi
       title: COVID-19 and neurological disorders: are neurodegenerative or neuroimmunological diseases more vulnerable?
        date: 2020-07-21
       words: 6804
      flesch: 33
     summary: The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients Middle East respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4 Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system Angiotensin type 2 receptors: role in aging and neuroinflammation in the substantia nigra Cerebrospinal fluid antibodies to coronavirus in patients with Parkinson's disease Outcome of Parkinson's disease patients affected by COVID-19 Staging of brain pathology related to sporadic Parkinson's disease Movement disorders in the world of COVID-19 Management of advanced therapies in Parkinson's disease patients in times of humanitarian crisis: the COVID-19 experience Impact of the COVID-19 pandemic on Parkinson's disease and movement disorders Influence of Parkinsonism on outcomes of elderly pneumonia patients Effects of COVID-19 on Parkinson's disease clinical features: a community-based case-control study Incidence of anxiety in parkinson's disease during the coronavirus disease (COVID-19) pandemic The impact of the COVID-19 pandemic on Parkinson's disease: hidden sorrows and emerging opportunities Effect of high-intensity treadmill exercise on motor symptoms in patients with de novo Parkinson disease Effectiveness of home-based and remotely supervised aerobic exercise in Parkinson's disease: adouble-blind, randomised controlled trial Mental health, physical activity, and quality of life in Parkinson's disease during COVID-19 pandemic Parkinson's disease and COVID-19: perceptions and implications in patients and caregivers Increased dependence of action selection on recent motor history in Parkinson's disease Cognitive deficits in Parkinson's disease: a cognitive neuroscience perspective Movement disorder societyunified Parkinson's disease rating scale use in the covid-19 Era E-Rehabilitation: One Solution for Patients With Parkinson's Disease in COVID-19 Era Implementation of telemedicine for urgent and ongoing healthcare for patients With Parkinson's disease during the COVID-19 pandemic: new expectations for the future Is the brain a reservoir organ for SARS2-CoV2? Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation Transient aggregation of ubiquitinated proteins is a cytosolic unfolded protein response to inflammation and endoplasmic reticulum stress The possible protective role of α-synuclein against the SARS-CoV-2 infections in patients with Parkinson's disease Lack of alpha-synuclein modulates microglial phenotype in vitro Qualitative and quantitative ultrastructural analysis of the membrane rearrangements induced by coronavirus Conductance and amantadine binding of a pore formed by a lysineflanked transmembrane domain of SARS coronavirus envelope protein The G8 dementia research summita starter for eight? Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy Clinical features of COVID-19 in elderly patients: a comparison with young and middle-aged patients Risk factors for predicting mortality in elderly patients with COVID-19: a review of clinical data in China Coronavirus disease 2019 in elderly patients: characteristics and prognostic factors based on 4-week follow-up Clinical characteristics and prognostic factors in COVID-19 patients aged ≥80 years Clinical presentation of COVID19 in dementia patients Neuropsychiatric disturbance in Alzheimer's disease clusters into three groups: the cache county study The effects of confinement on neuropsychiatric symptoms in Alzheimer's disease during the COVID-19 crisis Neuropsychiatric signs and symptoms of Alzheimer's disease: new treatment paradigms Neuropsychiatric symptoms and quality of life in spanish patients with Alzheimer's disease during the COVID-19 lockdown Atypical presentation of covid-19 in an older adult with severe Alzheimer disease Delirium in hospitalized older adults Telemedicine in neurology: telemedicine work Group of the American Academy of neurology update Dementia care and COVID-19 pandemic: a necessary digital revolution Disability through COVID-19 pandemic: neurorehabilitation cannot wait Potential novel role of COVID-19 in Alzheimer's disease and preventative mitigation strategies A claims databased comparison of comorbidity in individuals with and without dementia Barrientos RMThe impact of nutrition on COVID-19 susceptibility and long-term consequences Anticipating and mitigating the impact of the COVID-19 pandemic on alzheimer's disease and related dementias Multiple sclerosis and the risk of infection: considerations in the threat of the novel coronavirus, COVID-19/SARS-CoV-2 Infections in patients diagnosed with multiple sclerosis: A multi-database study Infection risks among patients with multiple sclerosis treated with fingolimod, natalizumab, rituximab, and injectable therapies Disease-modifying drugs for multiple sclerosis and infection risk: a cohort study Risk of COVID-19 infection in MS and neuromyelitis optica spectrum disorders COVID-19 pandemic and the risk of infection in multiple sclerosis patients on disease modifying therapies: what the bleep do we know? Taken together, these finding suggest dementia, especially in the advanced stages of the disease, might represent an important risk factor for mortality in COVID-19 patients (Fig. 1) .
    keywords: age; covid-19; dementia; disease; disorders; infection; pandemic; patients; risk; sars
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        item: #2744 of 7819
          id: cord-285579-gvgt55o4
      author: Asif, Rehan
       title: Rare complication of COVID-19 presenting as isolated headache
        date: 2020-10-29
       words: 1414
      flesch: 46
     summary: A scoping review Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study Cerebral venous thrombosis associated with COVID-19 Cerebral venous sinus thrombosis as a presentation of COVID-19 Contributors RA was involved in the planning, literature search design and writing of the case report. key: cord-285579-gvgt55o4 authors: Asif, Rehan; O' Mahony, Marcella Sinead title: Rare complication of COVID-19 presenting as isolated headache date: 2020-10-29 journal: BMJ Case Rep DOI: 10.1136/bcr-2020-239275 sha: doc_id: 285579 cord_uid: gvgt55o4 An 18-year-old man presented with persistent isolated headache 2 weeks after recovering from acute COVID-19 illness.
    keywords: covid-19; headache; risk; thrombosis
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        item: #2745 of 7819
          id: cord-285580-gq7400tq
      author: Pieretti, Joana C.
       title: Nitric oxide (NO) and nanoparticles – potential small tools for the war against COVID-19 and other human coronavirus infections
        date: 2020-10-18
       words: 4886
      flesch: 37
     summary: The use of NO donors and nanomaterials increases the stability of NO and enables targeted, controlled NO release at desirable concentrations, which is fundamental for NO bioactivity (Quinn et al., 2015) . NO has already been reported as a potential candidate for the treatment against coronaviruses and other respiratory viral diseases, such as influenza (Arabi et al., 2015; Keyaerts et al., 2004; Murphy et al., 1998) .
    keywords: covid-19; donors; et al; nitric; oxide; patients; sars; treatment
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        item: #2746 of 7819
          id: cord-285588-ug7upa3r
      author: Ajibade, Ayomikun
       title: Telemedicine in cardiovascular surgery during COVID‐19 pandemic: A systematic review and our experience
        date: 2020-08-16
       words: 4143
      flesch: 29
     summary: The FIT@Home study conducted a 12-week home-based exercise training program for cardiac surgery patients, where patient status was tracked using a remote heart-rate monitor and regular telephone support. Combinations of regular virtual consultations and remote monitoring of clinical parameters are feasible for cardiac surgery patients and would be useful to assess and triage before surgery.
    keywords: cardiac; covid-19; health; heart; monitoring; pandemic; patients; surgery; telemedicine; use
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        item: #2747 of 7819
          id: cord-285642-43sqmffe
      author: Topriceanu, C.-C.
       title: Inequality in access to health and care services during lockdown - Findings from the COVID-19 survey in five UK national longitudinal studies
        date: 2020-09-14
       words: 4911
      flesch: 46
     summary: A web and telephone-based survey provided data on cancelled surgical or medical appointments, and the number of care hours received during the UK COVID-19 national lockdown. Ethnic minorities and those with a chronic illness required a higher number of care hours during the lockdown (both OR approx.
    keywords: care; cohorts; covid-19; health; hours; lockdown; participants; sex
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        item: #2748 of 7819
          id: cord-285681-nv1aa116
      author: Lesniewski, Andrew
       title: Estimating population immunity without serological testing
        date: 2020-04-26
       words: 1225
      flesch: 58
     summary: [2] and references therein: The symptoms of COVID-19 infection appear after an incubation period of approximately 5.2 days. key: cord-285681-nv1aa116 authors: Lesniewski, Andrew title: Estimating population immunity without serological testing date: 2020-04-26 journal: nan DOI: 10.1101/2020.04.23.20076786 sha: doc_id: 285681 cord_uid: nv1aa116 We propose an approximate methodology for estimating the overall level of immunity against COVID-19 in a population that has been affected by the recent epidemic.
    keywords: covid-19; preprint
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        item: #2749 of 7819
          id: cord-285711-2utcn0hw
      author: Elliott, Robert
       title: COVID-19 Related Mortality During Management of a Hepatic Abscess
        date: 2020-09-22
       words: 2073
      flesch: 37
     summary: Should mandates related to in-hospital universal masking eventually ease, we hope that safeguards are in place such that our healthcare systems can quickly J o u r n a l P r e -p r o o f reintegrate universal masking; one option we put forth might be to follow disease activity in the region such that when some arbitrary threshold is passed, we return to universal hospital masking. For background, the need for universal masking is driven by what appears to be a feature of Covid-19 such that asymptomatic or paucisymptomatic individuals appear to be able to harbor significant viral loads.
    keywords: covid-19; hospital; masking; patient; universal
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        item: #2750 of 7819
          id: cord-285726-eav5gr3y
      author: Tran, B. X.
       title: Studies of Novel Coronavirus Disease 19 (COVID-19) Pandemic: A Global Analysis of Literature
        date: 2020-05-08
       words: 3468
      flesch: 50
     summary: This paper informed the rapid growth of research publications, the global variation in research productivity, and research interests. https://doi.org/10.1101/2020.05.05.20092635 doi: medRxiv preprint By using the natural language processing approach with the Latent Dirichlet allocation, this study was able to capture the focus of COVID-19 related publications in different settings.
    keywords: covid-19; license; medrxiv; perpetuity; preprint; research; version
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        item: #2751 of 7819
          id: cord-285729-plbv62nz
      author: Lucchetti, Giancarlo
       title: Spirituality, religiosity and the mental health consequences of social isolation during Covid-19 pandemic
        date: 2020-11-02
       words: 3787
      flesch: 39
     summary: After adjustment: (a) participating in private religious activities was associated with lower levels of fear (OR = 0.632, CI 95%: 0.422-0.949, p < 0.05) and lower levels of worrying (OR = 0.466, CI 95%: 0.307-0.706, p < 0.001), (b) Higher levels of spiritual growth was associated with lower levels of fear (OR = 0.588, CI 95%: 0.392-0.882, p < 0.05), lower levels of worrying (OR = 0.667, CI 95%: 0.448-0.993, p < 0.05) and lower levels of sadness (OR = 0.646, CI 95%: 0.418-0.997, p < 0.01), (c) higher levels of religious attendance was associated with lower levels of worrying (OR = 0.587, CI95%: 0.395-0.871, p < 0.01), (d) improving religious activities was associated with lower levels of worrying (OR = 0.660, CI 95%: 0.442-0.986) and (e) all religious variables were associated with hoping in different degrees (ranging from OR = 1.706 to 3.615). Lower levels of worrying were associated with greater private religious activities (OR = 0.466, CI 95%: 0.307–0.706), religious attendance (OR = 0.587, CI 95%: 0.395–0.871), spiritual growth (OR = 0.667, CI 95%: 0.448–0.993) and with an increase in religious activities (OR = 0.660, CI 95%: 0.442–0.986); lower levels of fear were associated with greater private religious activities (OR = 0.632, CI 95%: 0.422–0.949) and spiritual growth (OR = 0.588, CI 95%: 0.392–0.882) and, lower levels of sadness (OR = 0.646, CI 95%: 0.418–0.997) were associated with spiritual growth.
    keywords: covid-19; health; isolation; pandemic
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        item: #2752 of 7819
          id: cord-285731-nr7fmydo
      author: Mikhael, Ehab Mudher
       title: Can developing countries face novel coronavirus outbreak alone? The Iraqi situation
        date: 2020-11-30
       words: 1724
      flesch: 46
     summary: Iraqi outdated public healthcare settings are already overwhelmed with many acute injuries from ongoing unrest. Iraqi outdated public healthcare settings are already overwhelmed with many acute injuries from ongoing unrest.
    keywords: cases; covid-19; healthcare; iraq
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        item: #2753 of 7819
          id: cord-285739-0enn5bzn
      author: Gutiérrez Rodríguez, José
       title: Variables asociadas a mortalidad en una población de pacientes mayores de 80 años y con algún grado de dependencia funcional hospitalizados por COVID-19 en un Servicio de Geriatría
        date: 2020-07-16
       words: 3927
      flesch: 35
     summary: El día 30 de enero de 2020 la Organización Mundial de la Salud (OMS) declaró el brote de nuevo coronavirus 2019 (nCoV) en China como una Emergencia de Salud Pública de Importancia Internacional 1 . Tal como en otros estudios se ha objetivado, esta técnica microbiológica presenta ciertas limitaciones (momento de recogida de la muestra con respecto al inicio de los síntomas, muestra insuficiente o deterioro de la misma) que disminuyen la capacidad de diagnosticar la totalidad de los casos.
    keywords: años; cognitivo; como; con; coronavirus; cov-2; covid-19; del; dependencia; deterioro; estudio; funcional; las; los; mayores; mortalidad; pacientes; patients; población; por; que; sars; una
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        item: #2754 of 7819
          id: cord-285748-us5do6c2
      author: Cheng, Yongqian
       title: SARS-CoV-2-Related Kidney Injury: Current Concern and Challenges
        date: 2020-09-23
       words: 5333
      flesch: 44
     summary: The prevalence of CKD was 0-5.6%, which represents a minor proportion in COVID-19 patients [6, [8] Some studies about renal function in COVID-19 patients have shown common manifestations of kidney dysfunctions and incidental acute kidney injury
    keywords: ace2; ckd; covid-19; disease; infection; injury; kidney; patients; renal; sars; study
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        item: #2755 of 7819
          id: cord-285755-zblitbo0
      author: Zhang, F.
       title: Myocardial injury is associated with in-hospital mortality of confirmed or suspected COVID-19 in Wuhan, China: A single center retrospective cohort study
        date: 2020-03-24
       words: 3071
      flesch: 37
     summary: Studies focused on cardiac injury in COVID-19 patients are scarce. Short-term prognosis of COVID-19 patients are discrepancy and in-hospital mortality risk are high in severe cases[1]
    keywords: cardiac; covid-19; ctni; disease; hospital; injury; patients
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        item: #2756 of 7819
          id: cord-285772-4xt4anq5
      author: Huang, Rui
       title: Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: A retrospective, multi-center study
        date: 2020-05-08
       words: 3382
      flesch: 56
     summary: The age of severe patients was comparable with non-severe patients (median age 49.0 yr vs. 44.0 yr, P = 0.066) and the BMI index of severe patients was higher than non-severe patients (median BMI, 26.4 kg/m 2 vs. 24.2 kg/m 2 , P = 0.004). [ Compared to non-severe patients, severe patients presented higher percentage of shortness of breath (7.3% vs. 26.1%, P = 0.004), lower lymphocytes (median 0.8 ×10 9 /L vs. 1.2×10 9 /L, P<0.001) and albumin (ALB) levels (median 38.1 g/L vs. 41.1 g/L, P = 0.002).
    keywords: clinical; coronavirus; covid-19; patients; severe; study; wuhan
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        item: #2757 of 7819
          id: cord-285806-363ivs67
      author: Magro, Giuseppe
       title: SARS-CoV-2 and COVID-19: is interleukin-6 (IL-6) the 'culprit lesion' of ARDS onset? What is there besides Tocilizumab? SGP130Fc
        date: 2020-05-14
       words: 5173
      flesch: 27
     summary: This diagram shows the classic signaling pathway (mediated by the membrane-bound form of IL-6 receptor, mIL6R) which is believed to be the antiinflammatory one and the trans-signaling pathway (mediated by the soluble form of IL-6 receptor, sIL6-R) which is believed to be the pro-inflammatory one. Since all cells express gp130, all of them are in theory possible target cells of IL-6 trans signaling 52 .
    keywords: cells; covid-19; disease; il-6; inflammatory; interleukin-6; pathway; patients; receptor; sars; signaling; trans
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        item: #2758 of 7819
          id: cord-285818-eh12luma
      author: Louis, Shreya
       title: Continuous Electroencephalography Characteristics and Acute Symptomatic Seizures in COVID-19 Patients
        date: 2020-08-26
       words: 3434
      flesch: 46
     summary: This high percentage of epileptiform abnormalities (EAs) in a specific brain region in COVID-19 patients behooves the question if this is a potential epileptic effect from the SARS-CoV-2 infection or if this is a limitation with the EEG requisition method itself; since patients did not receive the minimum required 21-electrode clinical EEG recommended by American Clinical Neurophysiological Society ACNS) (Sinha et al. 2016) . Since the primary aim was to characterize the cEEG findings of COVID-19 patients, we did not include patients with clinical concerns for COVID-19 disease who tested negative.
    keywords: ceeg; covid-19; findings; patients; seizures
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        item: #2759 of 7819
          id: cord-285820-g8b7u3yf
      author: Taxonera, Carlos
       title: Innovation in IBD Care During the COVID-19 Pandemic: Results of a Cross-Sectional Survey on Patient-Reported Experience Measures
        date: 2020-08-19
       words: 2798
      flesch: 40
     summary: Telemedicine for Covid-19 AGA clinical practice update on management of inflammatory bowel disease during the COVID-19 pandemic: expert commentary British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic Increased incidence of systemic serious viral infections in patients with inflammatory bowel disease associates with active disease and use of thiopurines Opportunistic infections with anti-tumor necrosis factor-α therapy in inflammatory bowel disease: meta-analysis of randomized controlled trials Inflammatory bowel disease care in the COVID-19 pandemic era: the Humanitas, Milan experience Challenges in the care of IBD patients during the CoViD-19 pandemic: report from a Red Zone area in Northern Italy Maintaining the quality standards of care for inflammatory bowel disease patients during the COVID-19 pandemic Novel Coronavirus Disease (COVID-19) in patients with inflammatory bowel diseases Feasibility and acceptance of a home telemanagement system in patients with inflammatory bowel disease: a 6-month pilot study Telemedicine for management of inflammatory bowel disease (myIBDcoach): a pragmatic, multicentre, randomised controlled trial A randomized controlled trial of TELEmedicine for patients with inflammatory bowel disease (TELE-IBD) Delivering high value inflammatory bowel disease care through telemedicine visits Innovation in IBD care during the COVID-19 pandemic: results of a global telemedicine survey by the international organization for the study of inflammatory bowel disease Management of COVID-19 pandemic in Spanish inflammatory bowel disease units: results from a national survey The authors thank Dr. G. Morley for reviewing the English manuscript. 6, 7 Although several studies offer guidance on gold-standard strategies for improved care of IBD patients in western countries, outcomes of such strategies have not been evaluated.
    keywords: consultations; covid-19; face; ibd; patients; telephone
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        item: #2760 of 7819
          id: cord-285829-adz819gj
      author: Maneenop, Sakkakom
       title: The impacts of COVID-19 on the global airline industry:An event study approach
        date: 2020-08-27
       words: 3037
      flesch: 53
     summary: A recent study documents the impact of COVID-19 and employment in the airline industry (Sobieralski, 2020) , but the impact of the COVID-19 virus on airline stock prices has not yet been investigated. The results demonstrate that airline stock returns declined more significantly than the market returns after three major COVID-19 announcements were made.
    keywords: airline; covid-19; event; market; prices; returns; stock
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        item: #2761 of 7819
          id: cord-285872-rnayrws3
      author: Elgendi, Mohamed
       title: The Performance of Deep Neural Networks in Differentiating Chest X-Rays of COVID-19 Patients From Other Bacterial and Viral Pneumonias
        date: 2020-08-18
       words: 3456
      flesch: 46
     summary: We utilize an existing diagnostic technology (chest radiography) and preexisting neural networks (DarkNet-19) to detect imaging features of COVID-19 pneumonia. Our study aims to determine the optimal learning method, by investigating different types of pre-trained networks on a balanced dataset, for COVID-19 testing.
    keywords: accuracy; chest; covid-19; dataset; images; networks; ray
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        item: #2762 of 7819
          id: cord-285890-tbh54zju
      author: Yuan, Niu
       title: Investigation of adverse reactions in healthcare personnel working in Level 3 barrier protection PPE to treat COVID-19
        date: 2020-06-18
       words: 2649
      flesch: 39
     summary: key: cord-285890-tbh54zju authors: Yuan, Niu; Yang, Wei-Xia; Lu, Jian-Li; Lv, Zhang-Hong title: Investigation of adverse reactions in healthcare personnel working in Level 3 barrier protection PPE to treat COVID-19 date: 2020-06-18 journal: Postgrad Med J DOI: 10.1136/postgradmedj-2020-137854 sha: doc_id: 285890 cord_uid: tbh54zju PURPOSE OF THE STUDY: Junior (8.5 years of experience or fewer) healthcare personnel also experienced a higher rate of heat stress when compared with senior personnel (more than 8.5 years greater) (χ(2)=5.228, p=0.022).
    keywords: covid-19; healthcare; l3ppe; personnel; reactions; skin
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        item: #2763 of 7819
          id: cord-285897-ahysay2l
      author: Wu, Guangyao
       title: Development of a Clinical Decision Support System for Severity Risk Prediction and Triage of COVID-19 Patients at Hospital Admission: an International Multicenter Study
        date: 2020-07-02
       words: 3809
      flesch: 38
     summary: General quarantine and symptomatic treatment at home or mobile hospital can be used for most non-severe patients, while a higher level of care and fast track to the intensive care unit (ICU) is needed for severe patients. There were significant difference for the proportion of severe patients among low, medium, and high-risk groups in the five test datasets (Figure 5 ).
    keywords: admission; covid-19; features; hospital; illness; laboratory; model; patients; risk
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        item: #2764 of 7819
          id: cord-285922-4gge917e
      author: Yusuff, Hakeem
       title: Thrombosis and Coagulopathy in COVID-19 Patients Requiring Extracorporeal Membrane Oxygenation
        date: 2020-06-01
       words: 1723
      flesch: 24
     summary: A lack of resolution of the widespread thrombi may be an important factor in the prognosis of COVID-19 patients in ICU and various studies in patients with COVID-19 have consistently shown a strong association between elevated D-dimer levels and adverse overall outcomes. The associated increased risk of thrombosis and coagulopathy in ECMO patients is a result of a combination of processes driven by the disease occurring in synergy with the effect of the extracorporeal circuit on the coagulation system.
    keywords: covid-19; ecmo; extracorporeal; patients; support
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        item: #2765 of 7819
          id: cord-285944-8lapwnuw
      author: Suwanwongse, Kulachanya
       title: Hyperpyrexia in COVID‐19 patients
        date: 2020-06-10
       words: 2175
      flesch: 36
     summary: To date, the impact of hyperpyrexia on the clinical course and prognoses of COVID-19 patients has not yet been reported. ACE2 receptors are highly expressed in airway epithelia, lung parenchyma, and gastrointestinal epithelia explaining why dyspnea, cough, and GI complaints are predominately symptoms in COVID-19 patients [12] .
    keywords: cov-2; covid-19; hyperpyrexia; injury; patients; sars
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        item: #2766 of 7819
          id: cord-285946-1q4k5bnh
      author: Birk, Rubinder
       title: Low detection rate of pulmonary embolism in patients presenting to the emergency department with suspected coronavirus disease 2019 (COVID-19): a single-centre UK study
        date: 2020-09-23
       words: 3337
      flesch: 50
     summary: The detection rate of PE in COVID-19 patients was compared to patients undergoing CTPA for suspected PE only and for suspected COVID-19 with no COVID CT findings and negative PCR (control group 1); and CTPAs prior to the coronavirus pandemic (control group 2). The lancet Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Coexistent COVID-19 pneumonia and pulmonary embolism: challenges in identifying dual pathology Acute pulmonary embolism associated with COVID-19 pneumonia detected by pulmonary CT angiography Pulmonary embolism in COVID-19 patients: awareness of an increased prevalence Coronavirus Disease 2019 (COVID-19) CT Findings: A Systematic Review and Meta-analysis Imaging BSoT.
    keywords: covid-19; ctpa; group; patients; study
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        item: #2767 of 7819
          id: cord-285955-fzm6036f
      author: Nasir, N.
       title: Treatment of ARDS and hyperinflammation in COVID-19 with IL-6 antagonist Tocilizumab: a tertiary care experience from Pakistan
        date: 2020-06-26
       words: 2059
      flesch: 41
     summary: We conducted a retrospective descriptive study from Feb 2020 to May 2020 on COVID-19 patients with ARDS and hyperinflammation characterized by raised CRP and/or ferritin. While limited studies from China have shown improved outcomes in COVID-19 patients with hyperinflammation and ARDS 9 , a study from Italy did not show significant mortality benefit 10 .
    keywords: ards; covid-19; patients; preprint; tocilizumab
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        item: #2768 of 7819
          id: cord-285960-1zuhilmu
      author: Conly, John
       title: Use of medical face masks versus particulate respirators as a component of personal protective equipment for health care workers in the context of the COVID-19 pandemic
        date: 2020-08-06
       words: 4926
      flesch: 32
     summary: Copenhagen: World Health Organization Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS) Lack of SARS transmission among public hospital workers Epidemiologic study and containment of a nosocomial outbreak of severe acute respiratory syndrome in a medical center in Kaohsiung The outbreak of SARS at Tan tock Seng hospital--relating epidemiology to control Cluster of severe acute respiratory syndrome cases among protected health-care workers -Toronto, Canada Control measures for severe acute respiratory syndrome (SARS) in Taiwan Cluster of cases of severe acute respiratory syndrome among Toronto healthcare workers after implementation of infection control precautions: a case series Infection control and SARS transmission among healthcare workers World Health Organization.
    keywords: care; contact; cov-2; covid-19; health; masks; ppe; respirators; sars; transmission; use
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        item: #2769 of 7819
          id: cord-285979-ha5nszxi
      author: Rojas, Manuel
       title: Convalescent plasma in Covid-19: Possible mechanisms of action
        date: 2020-05-05
       words: 5827
      flesch: 37
     summary: C5a anaphylatoxins: a novel effector function of immunoglobulins Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis Anti-cytokine nature of natural human immunoglobulin: one possible mechanism of the clinical effect of intravenous immunoglobulin therapy Antibody-Dependent Enhancement of Viral Infections BT -Dynamics of Immune Activation in Viral Diseases Original antigenic sin: A comprehensive review Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins The convalescent sera option for containing COVID-19 Anti-inflammatory actions of intravenous immunoglobulin The FcRn inhibitor rozanolixizumab reduces human serum IgG concentration: A randomized phase 1 study Influence of FCRN expression on lung decline and intravenous immunoglobulin catabolism in common variable immunodeficiency patients The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease Effects of intravenous immunoglobulin on platelet count and antiplatelet antibody disposition in a rat model of immune thrombocytopenia Intravenous immunoglobulin mediates an increase in anti-platelet antibody clearance via the FcRn receptor FcγRIIb expression on B cells is associated with treatment efficacy for acute rejection after kidney transplantation Role of activating FcγR gene polymorphisms in Kawasaki disease susceptibility and intravenous immunoglobulin response Anti-inflammatory activity of immunoglobulin G resulting from Fc sialylation Sialylation may be dispensable for reciprocal modulation of helper T cells by intravenous immunoglobulin Inhibition of maturation and function of dendritic cells by intravenous immunoglobulin Intravenous immunoglobulin-induced IL-33 is insufficient to mediate basophil expansion in autoimmune patients Intravenous immunoglobulin treatment in humans suppresses dendritic cell function via stimulation of IL-4 and IL-13 production Therapeutic normal IgG intravenous immunoglobulin activates Wnt-β-catenin pathway in dendritic cells Intravenous immunoglobulin abrogates dendritic systemic lupus erythematosus Interferon-α inhibition by intravenous immunoglobulin is independent of modulation of the plasmacytoid dendritic cell population in the circulation: comment on the article by Wiedeman et al Indirect inhibition of in vivo and in vitro Tcell responses by intravenous immunoglobulins due to impaired antigen presentation Intravenous IgG (IVIG) and subcutaneous IgG (SCIG) preparations have comparable inhibitory effect on T cell activation, which is not dependent on IgG sialylation, monocytes or B cells Effect of Intravenous immunoglobulin on Th1 and Th2 lymphocytes and improvement of pregnancy outcome in recurrent pregnancy loss (RPL) Hyperimmune IV immunoglobulin treatment: a multicenter double-blind randomized controlled trial for patients with severe 2009 influenza A(H1N1) infection Effective treatment with intravenous immunoglobulins reduces autoreactive T-cell response in patients with CIDP Intravenous immunoglobulin modulates the expansion and cytotoxicity of CD8+ T cells Intravenous immunoglobulin treatment responsiveness depends on the degree of CD8+ T cell activation in Kawasaki disease Inhibition of differentiation, amplification, and function of human TH17 cells by intravenous immunoglobulin Comparison of different IVIg preparations on IL-17 production by human Th17 cells Intravenous immunoglobulin G modulates peripheral blood Th17 and Foxp3(+) regulatory T cells in pregnant women with recurrent pregnancy loss Impaired inhibitory Fcgamma receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy Intravenous immunoglobulin up-regulates the expression of the inhibitory FcgammaIIB receptor on B cells TLR9 responses of B cells are repressed by intravenous immunoglobulin through the recruitment of phosphatase Therapeutic preparations of normal polyspecific IgG (IVIg) induce apoptosis in human lymphocytes and monocytes: a novel mechanism of action of IVIg involving the Fas apoptotic pathway Inhibition of B cellmediated antigen presentation by intravenous immunoglobulins (IVIg) IVIg modulates BCR signaling through CD22 and promotes apoptosis in mature human B lymphocytes Imbalanced host response to SARS-CoV-2 drives development of COVID-19 Intravenous immunoglobulin skews macrophages to an antiinflammatory, IL-10-producing activation state High-dose intravenous immunoglobulins reduce nerve macrophage Immunotherapy in clinical medicine: historical perspective and current status Mechanisms of immunotherapy: a historical perspective IVIG in autoimmunity and cancer--efficacy versus safety Safety of intravenous immunoglobulin (IVIG) therapy Use of Convalescent Plasma Therapy in Two COVID-19 Patients with Acute Respiratory Distress Syndrome in Korea Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience Anti-Idiotypes to Autoantibodies in Therapeutic Preparations of Normal Polyspecific Human IgG (Intravenous Immunoglobulin, IVIg) Treatment with convalescent plasma for COVID-19 patients in Wuhan Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma Effectiveness of convalescent plasma therapy in severe COVID-19 patients Retrospective comparison of convalescent plasma with continuing highdose methylprednisolone treatment in SARS patients Use of convalescent plasma therapy in SARS patients in Hong Kong Experience of using convalescent plasma for severe acute respiratory syndrome among healthcare workers in a Taiwan hospital Epidemiologic features, clinical diagnosis and therapy of first cluster of patients with severe acute respiratory syndrome in Beijing area Letter to editor Treatment of severe acute respiratory syndrome with convalescent plasma Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection Hong Kong's experience on the use of extracorporeal membrane oxygenation for the treatment of influenza A (H1N1) Clinical characteristics of 26 human cases of highly pathogenic avian influenza A (H5N1) virus infection in China Successful treatment of avian influenza with convalescent plasma
    keywords: antibodies; cells; convalescent; coronavirus; covid-19; immunoglobulin; intravenous; ivig; patients; plasma; sars; treatment
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        item: #2770 of 7819
          id: cord-285993-n5fmah6a
      author: Stahl, Klaus
       title: Injury to the Endothelial Glycocalyx in Critically Ill Patients with COVID-19
        date: 2020-10-15
       words: 1865
      flesch: 35
     summary: Indeed, direct involvement of the vascular endothelium was recently reported in a series of patients suffering from severe COVID-19 (3) . We collected plasma and serum from 19 adult individuals within 24 hours after invasive ventilation for acute respiratory distress syndrome and from 10 healthy human donors after written informed consent of patients or their legal representative.
    keywords: covid-19; ecmo; egc; endothelial; patients
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        item: #2771 of 7819
          id: cord-286084-2275xvxb
      author: Dixit, Alok
       title: Ivermectin: Potential Role as Repurposed Drug for COVID-19
        date: 2020-08-19
       words: 2244
      flesch: 35
     summary: Apart from above discussed drugs, an additional drug which has property to inhibit the replication of RNA viruses found in several studies is ivermectin (IVM). Studies are available for its use against RNA virus and have also been tested for its effectiveness against SARS-CoV-2 in vitro.
    keywords: coronavirus; cov-2; covid-19; ivm; sars; treatment; virus; vitro
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        item: #2772 of 7819
          id: cord-286110-alix1s1w
      author: Fitzgerald, Dominic A.
       title: COVID-19 pandemic: Impact on children, families and the future
        date: 2020-06-27
       words: 1682
      flesch: 43
     summary: The Lancet Detection of Covid-19 in children in early Covid-19 in children: A brief overview after three months experience European and United Kingdom COVID-19 Pandemic Experience: The same but different Responses of Three Urban U.S. Children's Hospitals to COVID-19 COVID-19: The papers are consistent in highlighting the lessons learnt including a lack of preparedness for the COVID-19 pandemic despite recent experience on a smaller scale with SARS and MERS, a lack of action at decisive moments and the worrying partisan relationships between the WHO and high income countries which have undermined its ability to respond to such health crises and unite the world in its response.
    keywords: children; covid-19; impact; pandemic; paper
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        item: #2773 of 7819
          id: cord-286133-h8jgwe4z
      author: Gattinoni, Luciano
       title: Reply by Gattinoni et al. to Hedenstierna et al., to Maley et al., to Fowler et al., to Bhatia and Mohammed, to Bos, to Koumbourlis and Motoyama, and to Haouzi et al.
        date: 2020-08-15
       words: 1935
      flesch: 42
     summary: [online ahead of print Endothelial cell infection and endotheliitis in COVID-19 Hypercoagulability of COVID-19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis Mechanical ventilation to minimize progression of lung injury in acute respiratory failure Tidal volume reduction for prevention of ventilator-induced lung injury in acute respiratory distress syndrome: the Multicenter Trail Group on Tidal Volume reduction in ARDS Evaluation of a ventilation strategy to prevent barotrauma in patients at high risk for acute respiratory distress syndrome Prospective, randomized, controlled clinical trial comparing traditional versus reduced tidal volume ventilation in acute respiratory distress syndrome patients Fifty years of research in ARDS why is acute respiratory distress syndrome so important for critical care? Reply by Pan et al. to Haouzi et al. Dr. Bos, Dr. Maley and colleagues, and Dr. Haouzi and colleagues in their letters conclude, as do many others in our scientific community, that COVID-19 pneumonia is not atypical but fits the conventional ARDS definition and that higher respiratory system compliance (Crs) may be a normal finding in the syndrome.
    keywords: ards; covid-19; lung; patients
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        item: #2774 of 7819
          id: cord-286142-mx7u635d
      author: Ashby, Michael A.
       title: Life Goes On
        date: 2020-07-13
       words: 2056
      flesch: 43
     summary: Principles of biomedical ethics Human dignity and gene editing: Additional support for Raposo's arguments The principle of autonomy and behavioural variant frontotemporal dementia Ethical reasoning and moral distress in social care among long-term care staff Beyond money: Conscientious objection in medicine as a conflict of interests Deliver us from injustice: Reforming the U.S. healthcare system Mitochondrial donation: The Australian story Telling, hearing, and believing: A critical analysis of narrative bioethics Genome editing for longer lives: The problem of loneliness Symposium lead essay-Conflict of interest: Opening up new territories Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Risk management and protection of institutional interests and liabilities intrude and are often felt to influence care and ethical decision-making.
    keywords: autonomy; covid-19; ethics; lead; life; time
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        item: #2775 of 7819
          id: cord-286144-6wtk5y7c
      author: Tini, Giulia
       title: Semantic and Geographical Analysis of COVID-19 Trials Reveals a Fragmented Clinical Research Landscape Likely to Impair Informativeness
        date: 2020-06-29
       words: 2339
      flesch: 25
     summary: As COVID-19-devoted resources grow, quantifying the potential impact of COVID-19 trials becomes a relevant matter for global and national health policies. However, quality research on clinical trials is rendered difficult by the lack of a standardized definition of trial parameters.
    keywords: covid-19; enrolment; figure; research; study; trials
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        item: #2776 of 7819
          id: cord-286146-im42752g
      author: Nakamura, Hiroki
       title: Airport risk of importation and exportation of the COVID-19 pandemic
        date: 2020-07-01
       words: 3290
      flesch: 43
     summary: Gilbert et al. (2020) focused especially on Africa and estimated the risk of importation into each African country and the results show that Egypt, Algeria, and South Africa were the countries at highest importation risk from China; their study also assessed the African countries' capacity to detect and respond to COVID-19. Fig. 5 indicates that, while airports with the highest risk flow of importation are in East Asia near mainland China where the first case was confirmed, the airports with high exportation risk flow are located not only in mainland China and East Asia, but also in the Middle East and Europe, especially near Italy.
    keywords: covid-19; et al; importation; risk; travel
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        item: #2777 of 7819
          id: cord-286168-019rcbpg
      author: Vindegaard, Nina
       title: COVID-19 pandemic and mental health consequences: systematic review of the current evidence
        date: 2020-05-30
       words: 4110
      flesch: 33
     summary: The two studies investigating COVID-19 patients found a high level of post-traumatic stress symptoms (PTSS) (96.2%) and significantly higher level of depressive symptoms (p=0.016). Only two studies had investigated mental health issues in COVID-19 patients finding a high level of PTSS (96.2%) and significantly higher level of depressive symptoms (29.2%).
    keywords: covid-19; health; mental; patients; sars; studies; symptoms; workers
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        item: #2778 of 7819
          id: cord-286186-93atag0q
      author: Hansen, Jan-Cedric
       title: Commentaire cindynique sur l’épidémiologie de la pandémie COVID-19
        date: 2020-08-28
       words: 1922
      flesch: 52
     summary: On peut citer encore un travail critique d'une équipe française sur l'immunité de groupe et le contrôle de la pandémie COVID-19 sur la base du R0 qui alerte sur le fait que les modèles utilisés sont très simplificateurs et ne prennent en compte ni l'hétérogénéité de la population ni les conséquences délétères indirectes en termes de saturation des structures de santé la rend essentielle aux médecins, scientifiques, parties prenantes de la santé publique et décideurs politiques pour leur permettre des prises de décisions éclairées.
    keywords: cas; des; les; que; qui; une
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        item: #2779 of 7819
          id: cord-286193-3yy9exry
      author: Burton, Jennifer K
       title: Evolution and effects of COVID-19 outbreaks in care homes: a population analysis in 189 care homes in one geographical region of the UK
        date: 2020-10-31
       words: 6507
      flesch: 49
     summary: key: cord-286193-3yy9exry authors: Burton, Jennifer K; Bayne, Gwen; Evans, Christine; Garbe, Frederike; Gorman, Dermot; Honhold, Naomi; McCormick, Duncan; Othieno, Richard; Stevenson, Janet E; Swietlik, Stefanie; Templeton, Kate E; Tranter, Mette; Willocks, Lorna; Guthrie, Bruce title: Evolution and effects of COVID-19 outbreaks in care homes: a population analysis in 189 care homes in one geographical region of the UK date: 2020-10-31 journal: The Lancet Healthy Longevity DOI: 10.1016/s2666-7568(20)30012-x sha: doc_id: 286193 cord_uid: 3yy9exry Background COVID-19 has affected care home residents internationally, but detailed information on outbreaks is scarce. We obtained Care Inspectorate data for five variables: (1) type of care home, which was categorised into care homes for older people, care homes for other adult services (physical or sensory impairment, alcohol and drugs, mental health, respite care, or bloodborne viruses), care homes for people with learning disabilities, and care homes for children and young people; (2) number of beds, with number of registered places used as a proxy in 28 care homes where not available; (3) Risk Assessment Document score, which is a Care Inspectorate score to determine extent and frequency of inspection based on global assessment of care service quality and safety (low, medium, and high risk); 16 (4) care home ownership (private, voluntary or not for profit, and local authority); and (5) locality (ie, the Integration Joint Board or local authority in which the care home is located).
    keywords: care; care homes; covid-19; data; deaths; health; homes; nhs; outbreak; residents; testing
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        item: #2780 of 7819
          id: cord-286194-2emwfx89
      author: Mirzaei, Hossein
       title: COVID-19 Among People Living with HIV: A Systematic Review
        date: 2020-07-30
       words: 3049
      flesch: 43
     summary: From an initial 547 publications and 75 reports, 25 studies provided specific information on COVID-19 patients living with HIV. First, while a large proportion of COVID-19 patients are asymptomatic or have mild symptoms, all of the patients in this review were symptomatic, and most were admitted to a hospital.
    keywords: case; covid-19; disease; hiv; infection; patients; studies
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        item: #2781 of 7819
          id: cord-286220-0einpgeu
      author: Moreira, Diana Nadine
       title: The impact of the Covid-19 pandemic in the precipitation of intimate partner violence
        date: 2020-06-26
       words: 6057
      flesch: 37
     summary: European Psychiatry Responding to violence against women: Social science contributions to legal solutions Early career psychiatrists' perspectives on the mental health impact and care of the COVID-19 pandemic across the world Risk for domestic violence: Factors J o u r n a l P r e -p r o o f Journal Pre-proof associated with perpetration and victimization The relation of family violence, employment status, welfare benefits, and alcohol drinking in the United States Violence against women during covid-19 pandemic restrictions A systematic review of prevalence studies of gender-based violence in complex emergencies Intimate partner violence: Prevalence, health consequences, and intervention For domestic violence victims, coronavirus orders mean isolation with their abusers Domestic violence in the COVID-19 pandemic: a forensic psychiatric perspective Perceived Neighborhood Characteristics and Experiences of Intimate Partner Violence: A Multilevel Analysis COVID-19: Finally, it emphasizes the new challenges faced by health care professionals, while assisting IPV victims during the pandemic and provides possible recommendations on actions to implement during and beyond the Covid-19 pandemic to prevent such cases.
    keywords: covid-19; factors; health; ipv; pandemic; risk; victims; violence
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        item: #2782 of 7819
          id: cord-286222-8gfo2c87
      author: Chandra, Dr Prabha S
       title: COVID 19 related Psychosis as an interface of fears, socio-cultural issues and vulnerability- case report of two women from India
        date: 2020-05-27
       words: 1244
      flesch: 49
     summary: However, to our knowledge this is the first report of COVID related psychopathology in a woman with postpartum psychosis. Women who are vulnerable either due to personality factors, a family history or those in the perinatal period may be at risk for psychotic symptoms precipitated by high levels of COVID related anxiety (Wu et al., 2020) .
    keywords: covid; family; psychosis
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        item: #2783 of 7819
          id: cord-286227-foeb0g7u
      author: Potekaev, Nikolai N.
       title: Clinical characteristics of dermatologic manifestations of COVID‐19 infection: case series of 15 patients, review of literature, and proposed etiological classification
        date: 2020-07-03
       words: 1115
      flesch: 35
     summary: key: cord-286227-foeb0g7u authors: Potekaev, Nikolai N.; Zhukova, Olga V.; Protsenko, Denis N.; Demina, Olga M.; Khlystova, Elena A.; Bogin, Vlad title: Clinical characteristics of dermatologic manifestations of COVID‐19 infection: case series of 15 patients, review of literature, and proposed etiological classification date: 2020-07-03 journal: Int J Dermatol DOI: 10.1111/ijd.15030 sha: doc_id: 286227 cord_uid: foeb0g7u nan Presently, the exact dermatologic manifestations of COVID-19 infection, its characteristics, prevalence, temporal relationship to other clinical findings, and severity of underlying illness are still being evaluated. They excluded 60 of 148 patients from their study as they were taking new medications prior to developing symptoms of COVID-19 infection, indicating that a drug allergic reaction could not be excluded as a cause of their dermatologic presentation.
    keywords: covid-19; patient; year
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        item: #2784 of 7819
          id: cord-286237-x6dr6rsh
      author: Maes, Bastiaan
       title: Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial
        date: 2020-06-03
       words: 11261
      flesch: 42
     summary: Ethical and legal aspects The study will be conducted cfr the latest version of the ICH E6 (R2) GCP guidelines, creating a standard for the design, conduct, performance, monitoring, auditing, recording, analyses and reporting of clinical studies that provides assurance that the data and reported results are accurate and that the rights, integrity and confidentiality of study subjects are protected. Monitoring services will consist of the following (non-exhaustive list): -review of informed consents and the followed process -check on recruitment status -checking for protocol deviations/violations -checking GCP compatibility -check on safety reporting compliance -IMP handling and storage -review of study data … This study can be inspected at any time by regulatory agencies during or after completion of the study.
    keywords: anakinra; blood; care; covid-19; cytokine; data; days; hospital; il-1; il-6; improvement; injection; investigator; patients; siltuximab; study; subject; time; tocilizumab; treatment; trial; use
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        item: #2785 of 7819
          id: cord-286238-s64eueie
      author: Angelidis, G.
       title: A second wave of COVID-19 infections should not lead to a new disruption of services in nuclear cardiology
        date: 2020-08-06
       words: 523
      flesch: 38
     summary: After the gradual relaxation of lockdown measures in Greece, we have managed to provide nuclear cardiology services at patient flow levels comparable to that of the pre-COVID-19 era. Proper adjustments based on the epidemic status are required, but a second disruption of nuclear cardiology services should be avoided.
    keywords: covid-19; patients
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        item: #2786 of 7819
          id: cord-286241-ej9guh4d
      author: Kow, Chia Siang
       title: Interleukin-6 blockade with tocilizumab in COVID-19: Does it live up to its hype?
        date: 2020-10-21
       words: 324
      flesch: 32
     summary: J o u r n a l P r e -p r o o f Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review Tocilizumab among patients with COVID-19 in the intensive care unit: a multicentre observational study Tocilizumab in hospitalized patients with COVID-19 pneumonia Roche's phase III EMPACTA study showed Actemra/RoActemra reduced the likelihood of needing mechanical ventilation in hospitalised patients with COVID-19 associated pneumonia Is Interleukin 6 the Right Target in COVID-19 Severe Pneumonia? A recent prospective study by Blot et al. 5 compared the concentrations of IL-6 between 27 patients with COVID-19 pneumonia and 36 patients with non-COVID-19 pneumonia.
    keywords: covid-19
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        item: #2787 of 7819
          id: cord-286269-vrjyj2y1
      author: Sagheb, Setareh
       title: Two seriously ill neonates born to mothers with COVID-19 pneumonia- a case report
        date: 2020-09-21
       words: 2782
      flesch: 57
     summary: Furthermore, another study conducted on a limited number of patients showed a high level of SARS-COV-2 IgM in neonates born from COVID-19 infected mothers within 2 first hours of their birth [7] , which may indicate infection transmission from mother to fetus. It was reported that Severe Acute Respiratory Syndrome coronavirus 2 (SARS-COV-2) similar to SARS-COV and Middle East Respiratory Syndrome Coronavirus (MERS-COV), does not have vertical transmission from mother diagnosed with COVID-19 infection to her fetus
    keywords: birth; cov-2; covid-19; infection; neonates; pcr; sars
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        item: #2788 of 7819
          id: cord-286280-bxfea097
      author: Chang, Connie Y.
       title: Symptomatic COVID-19 infections in outpatient image-guided corticosteroid injection patients during the lockdown phase
        date: 2020-10-27
       words: 3678
      flesch: 36
     summary: The effectiveness of lumbar interlaminar epidural injections in managing chronic low back and lower extremity pain Results of 2-year follow-up of a randomized, double-blind, controlled trial of fluoroscopic caudal epidural injections in central spinal stenosis Intra-articular injections Recommendations of the British Society of Skeletal Radiologists: the safety of corticosteroid injections during the COVID-19 global pandemic British Society for Rheumatology: clinical guide for the management of patients with musculoskeletal and rheumatic conditions on corticosteroids during the coronavirus pandemic Caring for patients with pain during the COVID-19 pandemic: consensus recommendations from an international expert panel A COVID-19 epidemic model with latency period Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine New FactFinder on steriod injections and COVID-19 infection risk Systemic effects of intra-articular corticosteroids Corticosteroid and cortisol serum levels following intra-articular triamcinolone acetonide lumbar facet joint injections Intraarticular facet joint steroid injection-related adverse events encountered during 11,980 procedures Reopening Massachusetts: what businesses can expect in phase 1 Massachusetts State Government COVID-19 response reporting: COVID-19 daily dashboard Kenalog 10 injection (triamcinolone acetonide injectable suspension): uses, dosage, side effects, interactions, warning Joint corticosteroid injection associated with increased influenza risk The effect of local injection of methylprednisolone acetate on the hypothalamic-pituitary-adrenal axis among patients with greater trochanteric pain syndrome Reduction of cortisol levels after single intra-articular and intramuscular steroid injection Intra-articular glucocorticoid injections and their effect on hypothalamic-pituitaryadrenal (HPA)-axis function Intra-articular methylprednisolone acetate injection at the knee joint and the hypothalamicpituitary-adrenal axis: a randomized controlled study Adrenal insufficiency in corticosteroids use: systematic review and metaanalysis Hypothalamic pituitary adrenocortical axis suppression following a single epidural injection of methylprednisolone acetate The effect of epidural methylprednisolone acetate injection on the hypothalamicpituitary-adrenal axis Pharmacokinetics and pharmacodynamics of glucocorticoid suspensions after intra-articular administration Septic shock and sepsis: a comparison of total and free plasma cortisol levels Cortisol response in relation to the severity of stress and illness Influence of epidural steroid injection on adrenal function Fatal complications of intramuscular and intra-articular injections Use of corticosteroids in coronavirus disease 2019 pneumonia: a systematic review of the literature Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Back and joint pain are common debilitating problems, which can be treated with corticosteroid injections [1] [2] [3] .
    keywords: corticosteroid; covid-19; injection; pain; pandemic; patients; study; subjects
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        item: #2789 of 7819
          id: cord-286293-f5qg7vcz
      author: Ullah, Waqas
       title: COVID-19 complicated by Acute Pulmonary Embolism and Right-Sided Heart Failure
        date: 2020-04-17
       words: 1096
      flesch: 39
     summary: In the present case, the patient had elevated CRP and d-dimer levels with no other risk factor for pulmonary embolism, indicating COVID-19 related hypercoagulable state as possible etiology for thrombosis in the pulmonary vasculature. • To be able to make a differential diagnosis of pulmonary embolism in patients with COVID-19 with sudden onset of dyspnea and hypoxemia.
    keywords: covid-19; disease; embolism; patients
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        item: #2790 of 7819
          id: cord-286298-pn9nwl64
      author: Helmy, Yosra A.
       title: The COVID-19 Pandemic: A Comprehensive Review of Taxonomy, Genetics, Epidemiology, Diagnosis, Treatment, and Control
        date: 2020-04-24
       words: 9320
      flesch: 44
     summary: The other third of SARS CoV-2 includes four genes (in green) that encode four structural proteins (S, M, E, N), and six accessory genes (in blue) that encode six accessory proteins (orf3a, orf6, orf7a, orf7b, orf8, and orf10). While the SARS-CoV-2 S2 subunit was conserved, the S1 subunit shares an overall 70% identity with those of bat and human SARS-CoV.
    keywords: 2019; analysis; bat; cases; china; coronavirus; cov-2; covid-19; disease; genome; human; infection; mers; novel; patients; protein; rna; sars; transmission; viruses
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        item: #2791 of 7819
          id: cord-286335-benansqq
      author: Faqihi, Fahad
       title: Co-infection of SARS-CoV-2 and Bordetella bronchiseptica in a young man with idiopathic non-cystic bronchiectasis and vitamin D(3) deficiency
        date: 2020-08-28
       words: 989
      flesch: 34
     summary: A novel coronavirus from patients with pneumonia in China Co-infections in people with COVID-19: a systematic review and meta-analysis Coronavirus Disease 2019 (COVID-19) CT Findings: A Systematic Review and Meta-analysis Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Chest CT Findings in patients with corona virus disease 2019 and its relationship with clinical features Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2 Clinical and computed tomographic imaging features of novel coronavirus pneumonia caused by SARS-CoV-2 Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths Comparative performance of SARS-CoV-2 detection assays using seven different primer/probe sets and one assay kit Detection of SARS-CoV-2 in different types of clinical specimens Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Saudi Ministry of Health Processing and interpretation of lower respiratory tract specimens Performance standards for antimicrobial susceptibility testing: twenty-third informational supplement (M100-S23) Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Large prospective studies are required to investigate further the role of co-infections in COVID-19 patients with bronchiectasis.
    keywords: bronchiectasis; covid-19; patients; vitamin
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        item: #2792 of 7819
          id: cord-286341-16tghl48
      author: CONCHA-MEJIA, A.
       title: CCOFEE-GI Study: Colombian COVID19 First Experience in Gastroentrology. Characterization of digestive manifestations in patients diagnosed with COVID-19 at a highly complex institution in Bogota D.C., Colombia
        date: 2020-07-24
       words: 2014
      flesch: 39
     summary: Studies have reported digestive symptoms in patients with COVID-19 such as anorexia 39.7%-50.2%, diarrhea 2%-49.5%, nausea 1%-10.1%, vomiting 1%-15.9%, and abdominal pain 0.96%-6% (2, (7) (8) (9) (10) (11) (12) (13) . Patients with digestive symptoms have a long time from the onset of symptoms to admission to hospital services, and the presence of these gastrointestinal manifestations is associated with a longer duration and severity of the clinical presentation of COVID-19 (16) , with increased stay in the intensive care unit (10).
    keywords: cov-2; patients; preprint; sars; symptoms
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        item: #2793 of 7819
          id: cord-286365-fy0a8mb4
      author: ElHawary, Hassan
       title: Bibliometric Analysis of Early COVID-19 Research: The Top 50 Cited Papers
        date: 2020-10-13
       words: 2635
      flesch: 37
     summary: Global coalition to accelerate COVID-19 clinical research in resource-limited settings A bibliometric analysis of top-cited journal articles in obstetrics and gynecology The top 100 cited neurorehabilitation papers The research scientific community has reacted promptly as evidenced by an outstanding number of COVID-19 related publications.
    keywords: articles; coronavirus; covid-19; publications; research; sars
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        item: #2794 of 7819
          id: cord-286403-gdkwabcj
      author: Rosovsky, Rachel P.
       title: Diagnosis and Treatment of Pulmonary Embolism During the COVID-19 Pandemic: A Position Paper from the National PERT Consortium
        date: 2020-08-27
       words: 2366
      flesch: 29
     summary: Existing hospital transfer policies for PE patients, regardless of COVID-19 status, should incorporate the following: There must be a well-defined clinical benefit or resources or services that are not available at the sending hospital, such as intensive care unit care, endovascular intervention or surgical services, ECMO, and neurosurgical services. There is emerging evidence that COVID-19 infected patients are prone to thrombosis and pulmonary embolism (PE).
    keywords: care; covid-19; embolism; patients; pert; treatment
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        item: #2795 of 7819
          id: cord-286408-bhrrb5s7
      author: None
       title: Medical sequelae of COVID-19
        date: 2020-09-15
       words: 1202
      flesch: 39
     summary: key: cord-286408-bhrrb5s7 authors: nan title: Medical sequelae of COVID-19 date: 2020-09-15 journal: Because of the spread of the pandemic, even a small percentage of medical sequelae represent a nationwide public health problem.
    keywords: covid-19; disorders; patients; phase
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        item: #2796 of 7819
          id: cord-286413-a7wue2e3
      author: Cohen, Isaac V.
       title: Cardiac adverse events associated with chloroquine and hydroxychloroquine exposure in 20 years of drug safety surveillance reports
        date: 2020-11-05
       words: 3612
      flesch: 41
     summary: However, CQ and HCQ use has been associated with cardiac side effects, which is of concern due to the higher risk of COVID-19 complications in patients with heart related disorders, and increased mortality associated with COVID-19 cardiac complications. Other studies have observed COVID-19 cardiac complications such as fulminant myocarditis, ventricular tachycardia [28]
    keywords: cardiac; covid-19; data; hcq; patients; reports; sle; table; use
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        item: #2797 of 7819
          id: cord-286415-flo3dqsm
      author: Fried, Justin A.
       title: The Variety of Cardiovascular Presentations of COVID-19
        date: 2020-03-04
       words: 2879
      flesch: 42
     summary: Medications that prolong the QT interval are being considered for COVID-19 patients and may require closer monitoring in patients with underlying structural heart disease. Furthermore, the COVID-19 pandemic creates a challenge for the management of heart failure patients on the heart transplant waitlist, forcing physicians to balance the risks of delaying transplant with the risks of donor infection and uncertainty regarding the impact of posttransplant immunosuppression protocols.
    keywords: cardiac; case; covid-19; heart; patients; pressure
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        item: #2798 of 7819
          id: cord-286418-9ho5fg3h
      author: Jenkins, Ian
       title: Lessons from Walking the Medical Distancing Tightrope
        date: 2020-05-28
       words: 2625
      flesch: 42
     summary: Patient care and education at the University of California, San Diego Health System had to change just as dramatically. At all levels, physicians and administrators worried that the distancing pendulum had swung too far away from direct patient care.
    keywords: care; covid; distancing; experience; hcw; health; hospital; patient; risk
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        item: #2799 of 7819
          id: cord-286419-jyvj3mo2
      author: Rahaman Khan, Hasinur
       title: Countries are Clustered but Number of Tests is not Vital to Predict Global COVID-19 Confirmed Cases: A Machine Learning Approach
        date: 2020-04-29
       words: 2940
      flesch: 51
     summary: We also found that the number of tests by the country variable among other variables country, number of active cases, number of deaths, number of recovered patients, number of serious cases, and number of new cases is an unimportant variable to predict cumulative number of confirmed cases. A capsule network-based framework for identification of COVID-19 cases from X-ray images.
    keywords: cases; countries; covid-19; license; number; preprint
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        item: #2800 of 7819
          id: cord-286441-nl3kuqw3
      author: Murray, D. D.
       title: Design and implementation of the multi-arm, multi-stage Therapeutics for Inpatients with COVID-19 (TICO) platform master protocol: An Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) initiative
        date: 2020-11-12
       words: 5564
      flesch: 40
     summary: Two additional agents will enter the study in November 2020, with other agents planned. Two additional agents will enter the study in November 2020, with other agents planned.
    keywords: agents; covid-19; efficacy; license; medrxiv; preprint; protocol; safety; stage; study; tico
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        item: #2801 of 7819
          id: cord-286477-0euaaspo
      author: Li, Xiaochen
       title: Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan
        date: 2020-04-12
       words: 3244
      flesch: 51
     summary: Severe patients treated with corticosteroids had higher LDH level compared 283 with severe patients without corticosteroid use pre-admission (P<0.05). Cox proportional hazard regression model was used for survival analysis in severe patients.
    keywords: admission; cases; covid-19; data; patients; sars; study
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        item: #2802 of 7819
          id: cord-286485-tt9ysg0w
      author: Lucius, M.
       title: ROBUST COVID-19-RELATED CONDITION CLASSIFICATION NETWORK
        date: 2020-05-26
       words: 3265
      flesch: 39
     summary: Rather than recurrence Variation in false negative rate of rt-PCR based SARS-CoV-2 tests by time since exposure Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Sensitivity of chest CT for COVID-19: comparison to RT-PCR Artificial intelligence: a disruptive tool for a smarter medicine Deep learning for chest radiograph diagnosis: A retrospective comparison of the CheXNeXt algorithm to practicing radiologists Classification of COVID-19 in chest X-ray images using DeTraC deep convolutional neural network Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection The diagnostic evaluation of Convolutional Neural Network (CNN) for the assessment of chest X-ray of patients infected with COVID-19 explainable COVID-19 predictions based on chest X-ray images International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. Our system was able to differentiate COVID-19 positive related chest X-ray images from the other two classes (common pneumonia and normal) with Accuracy, TPR and TNR of 90%, 80% and 98%, respectively.
    keywords: author; chest; covid-19; funder; license; medrxiv; preprint
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        item: #2803 of 7819
          id: cord-286520-oh95lnf9
      author: Levi, Marcel
       title: Coronavirus Disease 2019 Coagulopathy: Disseminated Intravascular Coagulation and Thrombotic Microangiopathy—Either, Neither, or Both
        date: 2020-06-08
       words: 1678
      flesch: 28
     summary: Mean fibrinogen plasma concentration in COVID-19 patients are strikingly high, which is likely due to an acute phase response. 21 Histopathology from postmortem examinations in COVID-19 patients has shown typical microvascular plateletrich thrombotic depositions in small vessels of the lungs along the foci of local hemorrhage and accumulation and entrapment of inflammatory cells, such as neutrophils, in alveolar capillaries.
    keywords: coagulation; coronavirus; covid-19; levels; patients
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        item: #2804 of 7819
          id: cord-286523-4ip8er0h
      author: Grippaudo, Francesca Romana
       title: The impact of COVID-19 in plastic surgery departments: a comparative retrospective study in a COVID-19 and in a non-COVID-19 hospital
        date: 2020-08-26
       words: 3137
      flesch: 45
     summary: If yes, when? Are you in contact with anyone who has been confirmed to be COVID-19 posiƟve, or that are in quaranƟne for exposure to Study data shows the effects of the consequence of cancellation of plastic surgery elective surgeries in both hospitals during the lockdown, when the operating theatre was available only for such urgent procedures as melanoma or melanoma and SLNB removal or for post-traumatic reconstruction in PU1. In both units, visitors for day surgery patients were not allowed; for in-patients, only one visitor per room was allowed, after a ThermoScan check negative for fever.
    keywords: covid-19; hospital; pandemic; patients; plastic; procedures; study; surgery
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        item: #2805 of 7819
          id: cord-286525-0354438s
      author: Lee, Todd C.
       title: Tocilizumab versus the covid19 tempest: all’s well that ends well or much ado about nothing?
        date: 2020-09-29
       words: 1440
      flesch: 35
     summary: As such, the tocilizumab group was further along in the illness trajectory with a median of One of the unexpected findings from this study was an observed lack of benefit from steroids in contrast to the RECOVERY randomized controlled trial results [4] or a recent meta-analysis of steroid trials in critically ill patients. The phase III COVACTA trial (NCT04317092) found tocilizumab did not reduce mortality in hospitalized patients with severe COVID-19 pneumonia
    keywords: covid-19; patients; tocilizumab; trial
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        item: #2806 of 7819
          id: cord-286526-3070a2cy
      author: Raval, Jay S.
       title: Viscoelastic testing in COVID‐19: a possible screening tool for severe disease?
        date: 2020-05-22
       words: 414
      flesch: 22
     summary: Coronavirus disease (COVID-19) pandemic Practical diagnosis and treatment of suspected venous thromboembolism during COVID-19 Pandemic ISTH interim guidance on recognition and management of coagulopathy in COVID-19 COVID-19: consider cytokine storm syndromes and immunosuppression The pathogenesis and treatment of the 'cytokine storm' in COVID-19 D-dimer is associated with severity of coronavirus disease 2019: a pooled analysis The double hazard of bleeding and thrombosis in hemostasis from a clinical point of view: a global assessment by Rotational Thromboelastometry (ROTEM) Hypercoagulability of COVID-19 patients in intensive care unit. key: cord-286526-3070a2cy authors: Raval, Jay S.; Burnett, Allison E.; Rollins‐Raval, Marian A.; Griggs, Joseph R.; Rosenbaum, Lizabeth; Nielsen, Nathan D.; Harkins, Michelle S. title: Viscoelastic testing in COVID‐19: a possible screening tool for severe disease? date: 2020-05-22 journal: Transfusion DOI: 10.1111/trf.15847 sha: doc_id: 286526 cord_uid: 3070a2cy nan (79 mm), and FIBTEM (58 mm) tracings (normal 52-70 mm, 51-72 mm, and 10-24 mm, respectively), and clot formation time was shortened on the EXTEM tracing (39 seconds, normal 48-127 seconds) with an increased α angle (82°, normal 65-80°).
    keywords: covid-19
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        item: #2807 of 7819
          id: cord-286543-mtjk59rp
      author: Al-Zaman, Md. Sayeed
       title: Healthcare Crisis in Bangladesh during the COVID-19 Pandemic
        date: 2020-08-20
       words: 1814
      flesch: 53
     summary: Bangladesh hospitals forced to turn away patients Institute for Defence Studies and Analyses Bangladesh arrests hospital owner over fake coronavirus results COVID-19 fake certificates scam: JKG Healthcare's chairman Dr. Sabrina held How much the permission-based investigation in hospitals would be effective. Surprisingly, whereas many developed countries, including the United States, the United Kingdom, Italy, and Spain, have suffered greatly during the COVID-19 pandemic even with their highly efficient healthcare systems, many less developed countries with inadequate healthcare systems are surviving the crisis more easily.
    keywords: bangladesh; covid-19; health; healthcare; pandemic
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        item: #2808 of 7819
          id: cord-286544-ipmcqz8n
      author: Cheng, Biao
       title: Predictors of progression from moderate to severe COVID-19: a retrospective cohort
        date: 2020-07-02
       words: 1984
      flesch: 48
     summary: CONCLUSIONS: Higher levels of NLR and CRP at admission were associated with poor prognosis of moderate COVID-19 patients. However, randomized controlled trials (RCTs) are required to confirm the impact of drug treatment on moderate COVID-19 patients.
    keywords: covid-19; crp; nlr; patients; study
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        item: #2809 of 7819
          id: cord-286552-4ip0yl0n
      author: Romero, Carolina S.
       title: COVID-19 psychological impact in 3109 healthcare workers in Spain: The PSIMCOV group
        date: 2020-05-14
       words: 1177
      flesch: 47
     summary: Incremental validity of new clinical assessment measures Incremental validity in the psychological assessment of children and adolescents Impact on mental health and perception of psychological care among medical and nursing staff in Wuhan during the 2019 novel coronavirus disease outbreak: A cross-sectional study Mental health and the Covid-19 pandemic A multicenter study into burnout, perceived stress, job satisfaction, coping strategies, and general health among emergency department nursing staff Emotional attention, clarity, and repair: Exploring emotional intelligence using the trait meta-mood scale The hierarchical factor structure of the coping strategies inventory A novel approach of consultation on 2019 novel coronavirus (COVID-19)-related psychological and mental problems: Structured letter therapy The effects of social support on sleep quality of medical staff treating patients with coronavirus disease 2019 (COVID-19 Urgent need to develop evidence-based self-help interventions for healthcare workers in COVID-19 pandemic Comparison of the indicators of psychological stress in the population of Hubei province and non-endemic provinces in China during two weeks during the coronavirus disease 2019 (COVID-19) outbreak in Ana Tirado, MD, Hospital Infanta Leonor, Madrid (Spain); Francisco Verdú, MD, Hospital General de Valencia, Valencia (Spain); Enrique Zapater, MD, Hospital General de Valencia, Valencia (Spain). key: cord-286552-4ip0yl0n authors: Romero, Carolina S.; Delgado, Carlos; Catalá, Juan; Ferrer, Carolina; Errando, Carlos; Iftimi, Adina; Benito, Ana; de Andrés, Jose; Otero, Maria title: COVID-19 psychological impact in 3109 healthcare workers in Spain: The PSIMCOV group date: 2020-05-14 journal: Psychological medicine DOI: 10.1017/s0033291720001671 sha: doc_id: 286552 cord_uid: 4ip0yl0n BACKGROUND:
    keywords: healthcare; psas; stress; workers
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        item: #2810 of 7819
          id: cord-286560-lhbp4nn0
      author: Eckermann, Marina
       title: 3D virtual pathohistology of lung tissue from Covid-19 patients based on phase contrast X-ray tomography
        date: 2020-08-20
       words: 7518
      flesch: 44
     summary: For Covid-19 lung tissue, the scans were recorded at the GINIX endstation of the PETRA III storage ring (DESY, Hamburg). More generally, we claim that 3D histology analysis based on x-ray tomography and light sheet microscopy (Power and Huisken, 2017 ) is required to quantitatively understand functional tissue properties based on its 3D architecture.
    keywords: beam; blood; contrast; covid-19; figure; histology; lung; phase; ray; sample; tissue; tomography; volume
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        item: #2811 of 7819
          id: cord-286565-bmcsyfz9
      author: Akdeniz, Gulsum
       title: A Survey of Attitudes, Anxiety Status, and Protective Behaviors of the University Students During the COVID-19 Outbreak in Turkey
        date: 2020-07-15
       words: 4223
      flesch: 44
     summary: A Study on Immediate Mental Health Status and Psychoneuroimmunity Prevention Measures of Chinese Workforce The Genetic Links to Anxiety and Depression (GLAD) Study: Online recruitment into the largest recontactable study of depression and anxiety Anxiety sensitivity and emotion regulation as mechanisms of successful CBT outcome for anxietyrelated disorders in a naturalistic treatment setting A Longitudinal Study on the Mental Health of General Population during the COVID-19 Epidemic in China Public responses to the novel 2019 coronavirus (2019-nCoV) in Japan: mental health consequences and target populations The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus Learning to use statistical tests in psychology The use of psychological testing for treatment planning and outcomes assessment: General considerations The 2014 Ebola Outbreak and Mental Health: Current Status and Recommended Response An inventory for measuring clinical anxiety: Psychometric properties Turkish version of the Beck Anxiety Inventory: Psychometric properties Using Multivariate Statistics Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak Google searches for the keywords of wash hands predict the speed of national spread of COVID-19 outbreak among 21 countries Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: A scoping review Social reaction toward the 2019 novel coronavirus (COVID-19) The immediate psychological and occupational impact of the 2003 SARS outbreak in a teaching hospital Fear and stigma: the epidemic within the SARS outbreak An outbreak of fear rumours and stigma: Psychosocial support for the Ebola virus disease outbreak in West Africa The Fear of COVID-19 Scale: Development and Initial Validation Television viewing, computer game playing, and Internet use and self-reported time to bed and time out of bed in secondary-school children Internet overuse and excessive daytime sleepiness in adolescents Mobile phone use and stress, sleep disturbances, and symptoms of depression among young adults-a prospective cohort study Sleepy teens: social media use in adolescence is associated with poor sleep quality, anxiety, depression, and low self-esteem The association between social media use and sleep disturbance among young adults A four-wave, cross-lagged model of problematic internet use and mental health among Chinese college students: Disaggregation of within-person and between-person effects Reducing Nursing Student Anxiety in the Clinical Setting: An Integrative Review Type 1 interferons as a potential treatment against COVID-19 TreaTment for emerging viruses: Convalescent plasma and COVID-19 The SARS-CoV-2 vaccine pipeline: an overview Early Assessment of Anxiety and Behavioral Response to Novel Swine-Origin Influenza A(H1N1) Sex-specific clinical characteristics and prognosis of coronavirus disease-19 infection in Wuhan, China: A retrospective study of 168 severe patients Gender Differences in Patients With COVID-19: Focus on Severity and Mortality Characterize health and economic vulnerabilities of workers to control the emergence of COVID-19 in an industrial zone in Vietnam Mental Health Strategies to Combat the Psychological Impact of COVID-19 Beyond Paranoia and Panic As a matter of fact, a study by Filder Smith and Do Freedman also stated that social distances would reduce transmission, as such outbreak diseases require a certain intimacy of people (15) .
    keywords: anxiety; coronavirus; covid-19; disease; health; outbreak; respondents; status; study
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        item: #2812 of 7819
          id: cord-286573-k4khwvt7
      author: Peng, Michael
       title: The Role of the Ocular Tissue in SARS-CoV-2 Transmission
        date: 2020-10-02
       words: 4365
      flesch: 49
     summary: For example, COVID-19 patients or suspects with only mild respiratory or ocular symptoms might not seek medical assistance, especially if their visual function was not impaired. 2) Another limitation is the heterogeneity in sample collection methods. Similarly, our literature review showed that ocular viral detection rate ranged from 0% to 8% among confirmed COVID-19 patients (Table 1) .
    keywords: ace2; conjunctival; coronavirus; cov-2; covid-19; patients; sars; studies
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        item: #2813 of 7819
          id: cord-286576-nirg7jdq
      author: Wang, Jiangshan
       title: Separate Fever Clinics Prevent the Spread of COVID-19 and Offload Emergency Resources: Analysis from a large tertiary hospital in China
        date: 2020-04-06
       words: 3348
      flesch: 57
     summary: With this new criteria, the number of FC patients grew dramatically in the 40 days after January 20, 2020. As the number of FC patients grew All rights reserved.
    keywords: covid-19; disease; outbreak; patients; screening
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        item: #2814 of 7819
          id: cord-286638-bqxyb61p
      author: Singh, Awadhesh Kumar
       title: Diabetes in COVID-19: Prevalence, pathophysiology, prognosis and practical considerations
        date: 2020-04-09
       words: 4831
      flesch: 40
     summary: Based on these findings and acknowledging the higher morbidities and mortality associated with comorbidities, researchers have recently proposed that the course of treatment and prognosis of COVID-19 should be stratified based on the absence or presence of co-morbidities in to type A, B and C. While Type A represents COVID-19 patients with pneumonia with no comorbidities, Type B denotes COVID-19 pneumonia with comorbidities; and Type C denotes COVID-19 pneumonia with multi-organ dysfunction [30] . High prevalence of diabetes makes it an important comorbidity in patients with COVID-19.
    keywords: coronavirus; covid-19; diabetes; disease; glucose; infection; patients; pneumonia; risk; sars; study
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        item: #2815 of 7819
          id: cord-286644-fafqg4i3
      author: Paramore, Louise
       title: Delivering urgent urological surgery during the COVID‐19 pandemic in the United Kingdom: Outcomes from our initial 52 patients.
        date: 2020-05-14
       words: 1128
      flesch: 47
     summary: In addition, a HHFT standardised screening consent form for COVID-19 symptoms were included as part of the pre assessment ( Figure 1 ) and patients were excluded if any symptoms were present. Therefore the disease by the lockdown stage was likely already prevalent in the local community, and in particular the actual number of COVID-19 cases will be higher than the official confirmed cases as people with COVID-19 symptoms who did not require hospital admission will have neither been swabbed nor counted.
    keywords: cases; covid-19; patients
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        item: #2816 of 7819
          id: cord-286683-mettlmhz
      author: Ortiz-Prado, Esteban
       title: Clinical, molecular and epidemiological characterization of the SARS-CoV2 virus and the Coronavirus disease 2019 (COVID-19), a comprehensive literature review
        date: 2020-05-30
       words: 13331
      flesch: 37
     summary: medRxiv Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Temporal dynamics in viral shedding and transmissibility of COVID-19 Presumed asymptomatic carrier transmission of COVID-19 Potential presymptomatic transmission of SARS-CoV-2 Interferon-stimulated genes and their antiviral effector functions RIG-I in RNA virus recognition RNA recognition and signal transduction by RIG-I-like receptors Recognition of viral single-stranded RNA by Toll-like receptors Mechanisms of innate immune evasion in re-emerging RNA viruses Viral Innate Immune Evasion and the Pathogenesis of Emerging RNA Virus Infections Immunopathogenesis of coronavirus infections: implications for SARS Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology Middle East respiratory syndrome Interaction of SARS and MERS coronaviruses with the antiviral interferon response SARS and MERS: recent insights into emerging coronaviruses Dysregulation of immune response in patients with COVID-19 in Wuhan Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile Interleukin-1 receptor blockade is associated with reduced mortality in sepsis patients with features of the macrophage activation syndrome: Re-analysis of a prior Phase III trial A multicenter, randomized controlled trial for the efficacy and safety of tocilizumab in the treatment of new coronavirus pneumonia (COVID-19) Effects of chloroquine on viral infections: an old drug against today's diseases Chloroquine is a potent inhibitor of SARS coronavirus infection and spread In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Baricitinib as potential treatment for 2019-nCoV acute respiratory disease COVID-19: consider cytokine storm syndromes and immunosuppression. Three recent examples of these viral jumps include SARS CoV, MERS-CoV and SARS CoV-2 virus.
    keywords: acute; cases; cells; china; clinical; coronavirus; cov-2; covid-19; disease; health; human; infection; influenza; mers; ncov; novel; novel coronavirus; patients; pneumonia; protein; r n; responses; sars; study; syndrome; treatment; use; vaccine; wuhan
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        item: #2817 of 7819
          id: cord-286709-rend93ng
      author: Kim, D.H.
       title: Personal protective equipment availability and usage amongst pediatric otorhinolaryngologists during the COVID-19 pandemic: an international survey
        date: 2020-09-01
       words: 2534
      flesch: 48
     summary: N95 was the most commonly utilized PPE when dealing with COVID-19 patients (64.2% - 81.9% depending on aerosolization risk of the procedure). WHO had called for droplet precautions in low transmission risk procedures with COVID-19 patients 5 .
    keywords: agmp; covid-19; papr; patients; ppe; risk
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        item: #2818 of 7819
          id: cord-286740-1esvgcxp
      author: Singh, S.
       title: ASSESSING THE ROLE OF ZINC IN COVID-19 INFECTIONS AND MORTALITY: IS ZINC DEFICIENCY A RISK FACTOR FOR COVID-19?
        date: 2020-06-14
       words: 2168
      flesch: 44
     summary: Surprisingly, our analysis of the selected European countries indicated a consistently negative correlation of Zinc deficiency with COVID-19 cases per million population over the time period and indicated an almost significant correlation with the adverse outcome, i.e., death, which seemed improving with the passage of pandemic. Generally, the countries with higher Zn deficiency prevalence, e.g., Turkey (21.7%), Slovakia (16.3%), Czechia (11%), Estonia (10.5%), Germany (9%), Hungary (8.4%), Portugal (6.3%), Denmark (6.2%), Norway (6.2%) had reported lesser no of cases per million population as compared to lower Zinc deficiency prevalence countries, e.g., Iceland (3.1), France (3.9), Ireland (4%), UK (4.6%)
    keywords: countries; covid-19; deficiency; zinc
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        item: #2819 of 7819
          id: cord-286799-q9p5kg65
      author: Huang, Huang
       title: Prognostic Factors for COVID-19 Pneumonia Progression to Severe Symptoms Based on Earlier Clinical Features: A Retrospective Analysis
        date: 2020-10-05
       words: 3605
      flesch: 36
     summary: Interestingly, the levels of glutamate aminotransferase (ALT) and aspartate aminotransferase (AST) significantly increased for severe patients (P < 0.05). Can some routine clinical characteristics or/and laboratory measurements (or their combination) predict the occurrence of severe cases?
    keywords: cases; covid-19; factors; patients; pneumonia; rate
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        item: #2820 of 7819
          id: cord-286853-9gbel3pq
      author: Kim, Jiwon
       title: Prognostic Utility of Right Ventricular Remodeling Over Conventional Risk Stratification in Patients With COVID-19
        date: 2020-10-27
       words: 2131
      flesch: 24
     summary: key: cord-286853-9gbel3pq authors: Kim, Jiwon; Volodarskiy, Alexander; Sultana, Razia; Pollie, Meridith P.; Yum, Brian; Nambiar, Lakshmi; Tafreshi, Romina; Mitlak, Hannah W.; RoyChoudhury, Arindam; Horn, Evelyn M.; Hriljac, Ingrid; Narula, Nupoor; Kim, Sijun; Ndhlovu, Lishomwa; Goyal, Parag; Safford, Monika M.; Shaw, Leslee; Devereux, Richard B.; Weinsaft, Jonathan W. title: Prognostic Utility of Right Ventricular Remodeling Over Conventional Risk Stratification in Patients With COVID-19 date: 2020-10-27 journal: J Am Coll Cardiol DOI: 10.1016/j.jacc.2020.08.066 sha: doc_id: 286853 cord_uid: 9gbel3pq BACKGROUND: Coronavirus disease 2019 (COVID-19) is a growing pandemic that confers augmented risk for right ventricular (RV) dysfunction and dilation; the prognostic utility of adverse RV remodeling in COVID-19 patients is uncertain. Whereas this study supports premise of our study, limited sample size and laboratory data prohibited assessment of whether the predictive utility of adverse RV remodeling dysfunction was additive to that of biomarker derived prognostic markers, which was a focus of the current research.
    keywords: covid-19; dilation; dysfunction; patients; remodeling; study
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        item: #2821 of 7819
          id: cord-286854-0s7oq0uv
      author: Jin, Xi
       title: Virus strain from a mild COVID-19 patient in Hangzhou represents a new trend in SARS-CoV-2 evolution potentially related to Furin cleavage site
        date: 2020-07-03
       words: 6027
      flesch: 49
     summary: Further comparative alignment analysis of GZ02 (SARS viral strain), Wuhan-Hu-1 (the earliest sequenced SARS-CoV-2), RaTG13, HKU9-1 (the potential ancestor of SARS and SARS-CoV-2), HKU-1 and OC43 showed that the variation of FCS sequence had certain regularity in coronavirus evolution ( Figure 4(B) ). Phylogenetic analysis suggested that SARS, RATG13, and SARS-CoV-2 exhibited remarkable evolutionary divergence, with potential evolutionary branches within SARS-CoV-2 ( Figure 1(A) ).
    keywords: cell; coronavirus; cov-2; covid-19; expression; fcs; furin; protein; sars; site; wuhan; zj01
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        item: #2822 of 7819
          id: cord-286885-eih8a6ul
      author: Ali, Sheikh Muhammad Ebad
       title: One-house one-person testing: Strategical plan to limit COVID-19 spread in stage three in the developing world
        date: 2020-05-06
       words: 832
      flesch: 48
     summary: I request that researchers conduct cross-sectional studies to execute this plan, which could save lives by preventing local transmission from asymptomatic COVID-19 cases. As of April 23, 2020, 2,630,516 confirmed COVID-19 cases, along with 183,924 COVID-19 deaths and 58,139 COVID-19 patients in critical condition have been reported.
    keywords: cases; covid-19; transmission
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        item: #2823 of 7819
          id: cord-286887-s8lvimt3
      author: Nour, Majid
       title: A Novel Medical Diagnosis model for COVID-19 infection detection based on Deep Features and Bayesian Optimization
        date: 2020-07-28
       words: 3688
      flesch: 48
     summary: Building and deploying a medical AI system in four weeks Deep Transfer Learning based Classification Model for COVID-19 Disease COVID-19 detection using deep learning models to exploit Social Mimic Optimization and structured chest X-ray images using fuzzy color and stacking approaches Application of deep learning technique to manage COVID-19 in routine clinical practice using CT images: Results of 10 convolutional neural networks COVIDiagnosis-Net: Deep Bayes-SqueezeNet based diagnosis of the coronavirus disease 2019 (COVID-19) from X-ray images Automated detection of COVID-19 cases using deep neural networks with X-ray Predicting the growth and trend of COVID-19 pandemic using machine learning and cloud computing An automated Residual Exemplar Local Binary Pattern and iterative ReliefF based corona detection method using lung X-ray image Diagnosis of Coronavirus Disease 2019 (COVID-19) with Structured Latent Multi-View Representation Learning A Weakly-supervised Framework for COVID-19 Classification and Lesion Localization from Chest CT Deep Learning COVID-19 Features on CXR using Limited Training Data Sets Data Augmentation Using Auxiliary Classifier GAN for Application of breast cancer diagnosis based on a combination of convolutional neural networks, ridge regression and linear discriminant analysis using invasive breast cancer images processed with autoencoders Essentials for Radiologists on COVID-19: Dataset [22] , COVID-19 positive chest X-ray images from different articles and lastly chest X-ray
    keywords: covid-19; data; deep; detection; images; learning; model; ray
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        item: #2824 of 7819
          id: cord-286901-whvq8y1p
      author: Vidali, Sofia
       title: D-dimer as an indicator of prognosis in SARS-CoV-2 infection: a systematic review
        date: 2020-07-13
       words: 4281
      flesch: 31
     summary: D-dimer was increased and significantly higher in COVID-19 patients compared with healthy controls, in COVID-19 patients with severe disease or a composite end-point compared with non-severe disease, in ARDS compared with non-ARDS patients and in deceased ARDS patients compared with ARDS patients who survived (all p<0.001). COVID-19 patients treated with anticoagulants demonstrated lower mortality compared with those not treated (p=0.017).
    keywords: ards; coagulation; coronavirus; covid-19; dimer; disease; patients; sars; work
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        item: #2825 of 7819
          id: cord-286915-lhxg4vjn
      author: Keller, Brian C.
       title: Early COVID‐19 infection after lung transplantation
        date: 2020-06-11
       words: 862
      flesch: 36
     summary: The manifestations of COVID‐19 in solid organ transplant recipients are only beginning to be understood with cases reported to date in transplant recipients on chronic immunosuppression. The manifestations of COVID-19 in solid organ transplant recipients are only beginning to be understood with cases reported to date in transplant recipients on chronic immunosuppression.
    keywords: covid-19; lung; recipient; transplant
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        item: #2826 of 7819
          id: cord-286923-o4fj8kx0
      author: Berhan, Yifru
       title: What immunological and hormonal protective factors lower the risk of COVID-19 related deaths in pregnant women?
        date: 2020-07-18
       words: 4552
      flesch: 25
     summary: Emphatic E3 increases the production of anti-inflammatory cytokines (IL-10 and IL-5) and reduces the production of proinflammatory cytokines (like TNF-α) The immune modulating and anti-inflammatory actions of estradiol (E2) and estriol (E3) is also well noted during pregnancy.
    keywords: cells; covid-19; cytokines; disease; immune; inflammatory; pregnancy; risk; vitamin; women
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        item: #2827 of 7819
          id: cord-286932-2gjnpqqa
      author: Lee, Yung
       title: Impact of hospital lockdown secondary to COVID-19 and past pandemics on surgical practice: A living rapid systematic review
        date: 2020-11-12
       words: 2958
      flesch: 39
     summary: 13 Studies reporting outcomes of patients undergoing surgery during an epidemic-caused hospital lockdown and studies investigating the impact of lockdown on surgical HCW and surgical practice were included. Studies conducted during COVID-19 accounted for 98.6% of the included patients, while 1.2% were from studies during SARS, and 0.15% were from studies during MERS.
    keywords: care; covid-19; epidemics; hcw; measures; studies
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        item: #2828 of 7819
          id: cord-286957-qmh35xyy
      author: Aziz, Muhammad
       title: The Association of “Loss of Smell” to COVID-19: A systematic review and meta-analysis
        date: 2020-11-01
       words: 2413
      flesch: 49
     summary: In addition, loss of smell had a lower association with severe COVID-19 compared to COVID-19 patients without loss of smell. A total of 51 studies with 11074 confirmed COVID-19 patients were included.
    keywords: bookmark; covid-19; error; loss; patients; smell
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        item: #2829 of 7819
          id: cord-286958-e1ey31eo
      author: Patel, Urvish
       title: Early epidemiological indicators, outcomes, and interventions of COVID-19 pandemic: A systematic review
        date: 2020-08-15
       words: 5040
      flesch: 45
     summary: All studies that compared outcomes of interest in COVID-19 patients were included. Few studies [18, 91] , have reported abnormal liver function in COVID-19 patients, and we found 20% of patients had elevated ALT and AST.
    keywords: cases; cfr; characteristics; china; coronavirus; covid-19; deaths; disease; health; italy; patients; studies; testing
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        item: #2830 of 7819
          id: cord-286960-uz34fjyp
      author: Ali, Nurshad
       title: Role of vitamin D in preventing of COVID-19 infection, progression and severity
        date: 2020-06-20
       words: 4037
      flesch: 35
     summary: Vitamin D insufficiency affects the immune functions as vitamin D exerts an immunomodulation role [5] , increasing innate immunity by secretion of antiviral peptides [6, 7] , which improves mucosal defenses. The vitamin D deficiency pandemic: approaches for diagnosis, treatment and prevention Vitamin D in autoimmunity: molecular mechanisms and therapeutic potential Influence of vitamin d on islet autoimmunity and beta-cell function in type 1 diabetes Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions Modulation of the immune response to respiratory viruses by vitamin D Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1, 25-dihydroxyvitamin D3 Direct and indirect induction by 1, 25-dihydroxyvitamin D3 of the NOD2/CARD15-defensin β2 innate immune pathway defective in Crohn disease Epidemic influenza and vitamin D Cod liver oil, vitamin A toxicity, frequent respiratory infections, and the vitamin D deficiency epidemic Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey The association between vitamin D deficiency and community-acquired pneumonia:
    keywords: covid-19; infections; levels; risk; study; supplementation; vitamin
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        item: #2831 of 7819
          id: cord-286975-id5dn795
      author: Carlitz, Ruth D.
       title: Life Under Lockdown: Illustrating Tradeoffs in South Africa’s Response to COVID-19
        date: 2020-08-28
       words: 5101
      flesch: 50
     summary: In contrast to the United States, where partisanship has been shown to be a key determinant of mobility reductions and other efforts to contain the spread of disease (Grossman et al., 2020; Adolph et al., 2020) , party politics do not seem to feature prominently when it comes to explaining variation in mobility in South Africa. key: cord-286975-id5dn795 authors: Carlitz, Ruth D.; Makhura, Moraka N. title: Life Under Lockdown: Illustrating Tradeoffs in South Africa’s Response to COVID-19 date: 2020-08-28 journal: World Dev DOI: 10.1016/j.worlddev.2020.105168 sha: doc_id: 286975 cord_uid: id5dn795 This research note sheds light on the first three months of the COVID-19 outbreak in South Africa, where the virus has spread faster than anywhere else in the region.
    keywords: africa; cape; covid-19; government; lockdown; mobility; province; reductions; response; south; trends
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        item: #2832 of 7819
          id: cord-287011-yd8ayqgc
      author: Rajajee, Venkatakrishna
       title: Use of a Novel Negative-Pressure Tent During Bedside Tracheostomy in COVID-19 Patients
        date: 2020-08-07
       words: 3185
      flesch: 41
     summary: The majority of these box, drape, and tent devices do not generate negative pressure in the procedural space. Multiple innovative devices designed to decrease the risk of disease transmission during AGPs performed on COVID-19 patients have been reported [8] [9]
    keywords: care; covid-19; device; patients; pressure; procedure; tent; tracheostomy
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        item: #2833 of 7819
          id: cord-287027-ahoo6j3o
      author: Lai, Yuan
       title: Unsupervised Learning for County-Level Typological Classification for COVID-19 Research
        date: 2020-08-30
       words: 3464
      flesch: 44
     summary: Notably, non-urban counties have steeper slopes than urban counties, are hit later in the total pandemic timeline, and experience death rates higher than in urban areas. Figure 3c bins the counties by death rate slope, highlighting that most counties are classified as non-urban areas, and that these had a long-tail distribution of death rate growth slope as compared to urban counties.
    keywords: 2020; age; counties; county; covid-19; data; group; level; mobility
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        item: #2834 of 7819
          id: cord-287057-1g5i8li4
      author: Rabiller, G
       title: Radiofarmacia Hospitalaria en Argentina durante la pandemia de COVID-19. Criterios y fundamentos para la organización del trabajo
        date: 2020-09-12
       words: 2615
      flesch: 29
     summary: Según la OMS, durante la pandemia se deben considerar los siguientes puntos a fin de asegurar la salud del personal, de los pacientes y de las personas vinculadas, familiares, etc. En el escenario actual es posible que pacientes COVID-19 positivos o sospechosos requieran prácticas de Medicina Nuclear para lo cual se tomarán todas las medidas sanitarias adecuadas, con la finalidad de proteger al personal de salud que realice la práctica, asegurando así la continuidad de la prestación del servicio 5 .
    keywords: anticuerpos; como; con; covid-19; del; hospitalaria; inmunidad; las; linfocitos; los; pacientes; para; personal; por; que; radiofarmacia; trabajo; una
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        item: #2835 of 7819
          id: cord-287076-uxuff57y
      author: Wolfson, Julia A.
       title: Food Insecurity and COVID-19: Disparities in Early Effects for US Adults
        date: 2020-06-02
       words: 4467
      flesch: 49
     summary: Household Food Security in the United States ERR-270 Social determinants of health inequalities Food Insecurity And Health Outcomes No food for thought: Food insecurity is related to poor mental health and lower academic performance among students in California's public university system Food Insecurity: A Key Social Determinant of Health for Older Adults Food Insecurity and Body Mass Index: A Longitudinal Mixed Methods Study Food insecurity is inversely associated with diet quality of lower-income adults Trends in food insecurity for adults with cardiometabolic disease in the United States Food insecurity and emotional health in the USA: A systematic narrative review of longitudinal research Kaiser Family Foundation. Strikingly, 41.3% of adults with very low food security reported not having enough food to feed themselves or their family compared to 10.7% of adults with low food security, 3.1% of adults with marginal food security and 1.6% of adults with high food security.
    keywords: adults; covid-19; food; health; income; pandemic; security; status
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        item: #2836 of 7819
          id: cord-287091-a3nieh5p
      author: Kumar, Anuj
       title: Identification of phytochemical inhibitors against main protease of COVID-19 using molecular modeling approaches
        date: 2020-06-04
       words: 5560
      flesch: 39
     summary: For the MD simulation, we followed the protocol described by Gajula, 2008; Gajula et al., 2016; . MD simulations are one of proven in-silico methods for obtaining dynamic data at atomic spatial resolution and picoseconds or finer temporal resolution (Benson & Daggett, 2012; Gajula et al., 2016) .
    keywords: acid; binding; carvacrol; coronavirus; covid-19; docking; drug; energy; et al; molecules; protease; protein; sars; simulation; study
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        item: #2837 of 7819
          id: cord-287094-73o7xxgt
      author: Lechien, Jerome R.
       title: In Reference to Anosmia and Ageusia: Common Findings in COVID‐19 Patients
        date: 2020-06-30
       words: 592
      flesch: 34
     summary: This hypothesis would explain the fact that 44% of patients recover olfaction within the 14 days following the infection, which seems to be a rapid recovery rate in case of neuron injury. Anosmia and ageusia: common findings in COVID-19 patients Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study Olfactory and gustatory dysfunctions as a clinical presentation of mild to moderate forms of the coronavirus disease (COVID-19): a multicenter European study Position paper on olfactory dysfunction Strategies in recommending influenza vaccination in Europe and US Olfactory mucosal findings and clinical course in patients with olfactory disorders following upper respiratory viral infection Identification of viruses in patients with postviral olfactory dysfunction Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence ofencephalitisinmicetransgenicforhumanACE2 Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations Non-neural expression of SARS-CoV-2 entry genes in the olfactory epithelium suggests mechanisms underlying anosmia in COVID-19 patients 2 We agree about the importance to consider these symptoms in the COVID-19 infection but, regarding our European multicenter study investigating the prevalence of olfactory and gustatory dysfunctions in COVID-19 patients, 3 we believe that the prevalence is significantly higher than reported by Vaira et al.
    keywords: covid-19; patients
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        item: #2838 of 7819
          id: cord-287100-xkp8a9b9
      author: López-Díaz, Álvaro
       title: COVID-19 Infection During Pregnancy and Risk of Neurodevelopmental Disorders in Offspring: Time for Collaborative Research
        date: 2020-10-31
       words: 1395
      flesch: 18
     summary: Thus, the pandemic provides an unprecedented context for clinical and translational research to further explore the mechanisms underlying breakdowns in fetal neurodevelopment during maternal infection, unknown partly because of methodological constraints of previous studies (3, 6) . Such information would help determine the extent to which maternal infection, in addition to genetic vulnerability, contributes to an increased risk of neuropsychiatric disturbance in the offspring, and would improve our understanding of the role of immune-inflammatory mechanisms during pregnancy in the etiology of neurodevelopmental disorders (10).
    keywords: covid-19; infection; offspring; risk
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        item: #2839 of 7819
          id: cord-287102-o19uwryp
      author: Amit, Moran
       title: Clinical Course and Outcomes of Severe Covid-19: A National Scale Study
        date: 2020-07-18
       words: 4185
      flesch: 48
     summary: The following mortality rates have been found for Covid-19 patients in the ICU for whom outcome data are available (i.e., excluding patients who were still being treated in the ICU at the time of the report): 61% (Lombardy, Italy [2] ), 78% (New York City, NY, USA [4] ), 79% (Wuhan, China [11] ), 57% (Seattle, WA, USA [12] ), 85% (Washington state, USA [13] ), and 67% (China [3] )) Patients who died prior to ICU admission and patients without outcome data were excluded.
    keywords: age; covid-19; data; days; icu; israel; patients; years
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        item: #2840 of 7819
          id: cord-287136-3cml1shh
      author: Dopfer, Christian
       title: COVID-19 related reduction in pediatric emergency healthcare utilization – a concerning trend
        date: 2020-09-07
       words: 3804
      flesch: 45
     summary: key: cord-287136-3cml1shh authors: Dopfer, Christian; Wetzke, Martin; Zychlinsky Scharff, Anna; Mueller, Frank; Dressler, Frank; Baumann, Ulrich; Sasse, Michael; Hansen, Gesine; Jablonka, Alexandra; Happle, Christine title: COVID-19 related reduction in pediatric emergency healthcare utilization – a concerning trend date: 2020-09-07 journal: BMC Pediatr DOI: 10.1186/s12887-020-02303-6 sha: doc_id: 287136 cord_uid: 3cml1shh BACKGROUND: We examined the impact of the pandemic on pediatric emergency healthcare utilization.
    keywords: covid-19; diseases; emergency; fig; healthcare; pandemic; patients; pediatric
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        item: #2841 of 7819
          id: cord-287156-3plpi6i9
      author: Lassandro, Giuseppe
       title: Children in Coronaviruses’ Wonderland: What Clinicians Need to Know
        date: 2020-07-01
       words: 8034
      flesch: 36
     summary: Multisystem Inflammatory Syndrome in Children in COVID-19-associated immune thrombocytopenia Immune Thrombocytopenia (ITP) in a SARS-CoV-2 Positive Pediatric Patient Covid-19 and Children with Immune Thrombocytopenia: Emerging Issues Evans syndrome in a patient with COVID-19 COVID-19 infection associated with autoimmune hemolytic anemia Chest computed tomography in children with COVID-19 respiratory infection Clinical and CT imaging features of the COVID-19 pneumonia: Influenza Other Respir Viruses Epidemiology characteristics of human coronaviruses in patients with respiratory infection symptoms and phylogenetic analysis of HCoV-OC43 during 2010-2015 in Guangzhou Human Coronavirus Infections in Israel: Epidemiology, Clinical Symptoms and Summer Seasonality of HCoV-HKU1.
    keywords: acute; cases; children; clinical; coronavirus; covid-19; disease; east; human; infection; mers; middle; novel; patients; sars; symptoms; syndrome
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        item: #2842 of 7819
          id: cord-287161-hqrql1lh
      author: McGrail, D. E.
       title: COVID-19 Case Series at UnityPoint Health St. Lukes Hospital in Cedar Rapids, IA
        date: 2020-07-19
       words: 2238
      flesch: 44
     summary: The most common presenting symptoms in COVID-19 patients were dyspnea (80%), cough (74%), fever (68%), and nausea(35%). In summary, we hope the knowledge gained through this study will help provide further insights into the epidemiological, clinical, laboratory and treatment outcomes of COVID-19 patients hospitalized in a community-based hospital in Iowa.
    keywords: azithromycin; covid-19; hospital; hydroxychloroquine; patients; ventilation
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        item: #2843 of 7819
          id: cord-287176-1hm0ua2s
      author: Solarino, Biagio
       title: Covid-19 pandemic and pediatric healthcare policy in Italy: time for a change
        date: 2020-08-06
       words: 2047
      flesch: 44
     summary: Coming to pediatric health care, during COVID pandemic the access to pediatric ED sharply dropped to one-half. Current child healthcare system comprises three main levels of intervention: a) primary care; 2) secondary care in Pediatric Hospital Units; 3) tertiary pediatric children's hospital.
    keywords: care; children; covid-19; pandemic; system
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        item: #2844 of 7819
          id: cord-287191-e8073l9p
      author: Klompas, Michael
       title: Coronavirus Disease 2019 (COVID-19): Protecting Hospitals From the Invisible
        date: 2020-03-11
       words: 1333
      flesch: 40
     summary: We underappreciate that 30% to 50% of cases of community-acquired pneumonia are caused by viruses, that nosocomial transmission of respiratory viruses is common, and that routine respiratory viruses cause substantial morbidity and mortality that may not differ much from those caused by SARS-CoV-2 once minimally symptomatic COVID-19 is accounted for. Respiratory viruses infect millions of persons each year (about 10% of the population) and cause tens of thousands of deaths in the United States alone (10) .
    keywords: covid-19; patients; viruses
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        item: #2845 of 7819
          id: cord-287196-re4sosff
      author: Shahzad, Fakhar
       title: Perceived Threat of COVID-19 Contagion and Frontline Paramedics’ Agonistic Behaviour: Employing a Stressor–Strain–Outcome Perspective
        date: 2020-07-15
       words: 8758
      flesch: 44
     summary: Therefore, we investigated the impact of perceived COVID-19 threat in forecasting greater levels of physiological anxiety, depression, and emotional exhaustion among frontline paramedics, which may boost their agonistic behaviour. Our study concludes that the effect of perceived COVID-19 threat on predicting greater levels of physiological anxiety, depression, and emotional exhaustion among frontline healthcare paramedics may contribute to their agonistic behaviour.
    keywords: anxiety; behaviour; covid-19; depression; exhaustion; model; pandemic; paramedics; patients; pss; stress; study; support; threat
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        item: #2846 of 7819
          id: cord-287203-8ml2ic4a
      author: Moreno, G.
       title: Revisión sistemática sobre la utilidad pronóstica del dímero-D, coagulación intravascular diseminada y tratamiento anticoagulante en pacientes graves con COVID-19
        date: 2020-06-17
       words: 5296
      flesch: 32
     summary: y cada 24-48 horas como herramienta en la evaluación del pronóstico y de la progresión de la Cada vez es mayor el conocimiento sobre las alteraciones de la coagulación relativamente frecuentes en pacientes con COVID-19, especialmente en aquellos casos más severos. De acuerdo con el Comité Científico y de Estandarización de la ISTH, la CID se define como un síndrome adquirido en el que ocurre una activación intravascular de los sistemas de coagulación de manera sistémica, caracterizada por fenómenos trombóticos y/o hemorrágicos, junto con alteraciones características en valores de laboratorio, que se acompaña de desarrollo de disfunción orgánica, como expresión de la activación de la coagulación 37 (Tabla 3).
    keywords: cid; coagulación; como; con; coronavirus; covid-19; del; disease; dímero; enfermedad; estudios; evidencia; han; intravascular; las; los; mayor; mortalidad; niveles; pacientes; para; patients; por; que; sin; tratamiento; una
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        item: #2847 of 7819
          id: cord-287220-mpnuhqwg
      author: Giuliani, C.
       title: Breastfeeding during the COVID-19 pandemic: suggestions on behalf of Woman Study Group of AMD
        date: 2020-05-30
       words: 2760
      flesch: 41
     summary: Position Statement on Breastfeeding from the Italian Pediatric Societies Intrauterine vertical transmission of SARS-CoV-2: what we know so far A case report of neonatal COVID-19 infection in China Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Infants Born to Mothers With a New Coronavirus (COVID-19). Woman Study Group of AMD, after reviewing current knowledge about COVID-19 vertical transmission and the compatibility of breastfeeding in COVID-19 mother, the available recommendations from Health Care Organizations and main experts opinions, issued the following suggestions on breastfeeding during the COVID-19 pandemic, addressed both to mothers with and without diabetes It should be considered that following suggestions may change in the future when more evidence is acquired regarding SARS-Cov2 infection.
    keywords: breastfeeding; covid-19; infection; milk; mother; sars; women
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        item: #2848 of 7819
          id: cord-287221-oh7lnxwt
      author: Kock, Florian
       title: Understanding the COVID-19 tourist psyche: The Evolutionary Tourism Paradigm
        date: 2020-09-09
       words: 8389
      flesch: 35
     summary: Yet, despite its potential, the application of evolutionary psychology in tourism research is scant. We postulate that the investigation of tourists' COVID-19 psyche and the paradigm shift in tourists' behavior demands new theory-based mindsets to be leveraged in tourism research.
    keywords: behavior; covid-19; disease; motive; pandemic; pathogen; psychology; research; threat; tourism; tourists; travel
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        item: #2849 of 7819
          id: cord-287222-wojyisu0
      author: Zhou, Min
       title: Coronavirus disease 2019 (COVID-19): a clinical update
        date: 2020-04-02
       words: 5692
      flesch: 34
     summary: Unlike influenza pneumonia, which usually exhibited unilateral GGO and significant solid nodules, only 6% of COVID-19 patients had solid nodules A majority of COVID-19 patients showed normal leucocyte count, and nearly one third had leucopenia
    keywords: china; clinical; coronavirus; covid-19; disease; infection; novel; patients; plasma; pneumonia; sars; study; syndrome; treatment; ventilation
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        item: #2850 of 7819
          id: cord-287247-vv0zc0gd
      author: Gutman, Julie R.
       title: Malaria and Parasitic Neglected Tropical Diseases: Potential Syndemics with COVID-19?
        date: 2020-06-01
       words: 4251
      flesch: 33
     summary: Susceptibility to malaria in highly endemic areas differs by age: younger children are more vulnerable to malaria infections and at a higher risk for severe malaria. Importantly, malaria infections in endemic areas frequently result in chronic, afebrile disease in older children and adults.
    keywords: children; coronavirus; cov-2; covid-19; disease; infection; lmics; malaria; ntds; sars
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        item: #2851 of 7819
          id: cord-287281-x30fx97e
      author: Thorpy, Michael
       title: Management of Sleep Apnea in New York City during the COVID-19 Pandemic
        date: 2020-07-18
       words: 3639
      flesch: 49
     summary: There is currently no data on the prevalence of OSA in COVID-19 patients, however the profile of those with greater likelihood of death associated with COVID-19 is similar to our random sample of 112 PAP using OSA patients many of whom have cardiovascular disease, hypertension, obesity and diabetes mellitus. Management of OSA patients during the COVID-19 pandemic has been complicated by the closing of sleep centers due to concern over COVID-19 infection of staff or patients, and the need for clinical staff to attend to COVID-19 patients in other settings.
    keywords: apnea; covid-19; osa; outbreak; pap; patients; risk; sleep
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        item: #2852 of 7819
          id: cord-287303-b7vg439c
      author: Piché-Renaud, Pierre-Philippe
       title: Healthcare worker perception of a global outbreak of novel coronavirus (COVID-19) and personal protective equipment: Survey of a pediatric tertiary-care hospital
        date: 2020-08-12
       words: 3614
      flesch: 41
     summary: COVID-19 PPE training was done in person with a hands-on demonstration of donning and doffing by the nurse educators as well as by the Occupational Health and Safety team (ie, occupational hygienists). COVID-19-specific PPE training had the most significant impact on HCWs knowledge of PPE donning and doffing.
    keywords: care; contracting; covid-19; hcws; ipac; ppe; survey; work
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        item: #2853 of 7819
          id: cord-287321-1ro10ujr
      author: Alpaydin, Aylin Ozgen
       title: Clinical and Radiological Diagnosis of Non‐SARS‐CoV‐2 Viruses in the Era of Covid‐19 Pandemic
        date: 2020-08-08
       words: 3291
      flesch: 44
     summary: In this study, indeterminate CT diagnosis group was combined with atypical and typical for COVID-19 groups and analyzed for two options each to suggest better management of the indeterminate group. When the indeterminate CT diagnosis group was combined with the atypical for the COVID-19 group, the number of false-negative patients for SARS-CoV-2 was more (n=3) concerning the combination of indeterminate group and typical for COVID-19 group (n=1), in the cost of increased false-positive results (n=15).
    keywords: cov-2; covid-19; group; non; pathogens; patients; pneumonia; sars
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        item: #2854 of 7819
          id: cord-287336-jvc1e8cq
      author: Sass, J.
       title: The German Corona Consensus Dataset (GECCO): A standardized dataset for COVID-19 research
        date: 2020-07-29
       words: 2257
      flesch: 41
     summary: Methods: Based on previous work (e.g., the ISARIC-WHO COVID-19 case report form) and in coordination with experts from university hospitals, professional associations and research initiatives, data elements relevant for COVID-19 research were collected, prioritized and consolidated into a compact core dataset. Data elements and response options were mapped to SNOMED CT, LOINC, UCUM, ICD-10-GM and ATC, and FHIR profiles for interoperable data exchange were defined.
    keywords: covid-19; data; dataset; license; medrxiv; preprint
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        item: #2855 of 7819
          id: cord-287338-pws42iay
      author: Gendelman, Omer
       title: Continuous hydroxychloroquine or colchicine therapy does not prevent infection with SARS-CoV-2: Insights from a large healthcare database analysis
        date: 2020-05-05
       words: 2021
      flesch: 37
     summary: Pneumonia of unknown cause-C The Coronavirus Pandemic in Israel: Implications for Radiation Oncology Departments Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Clinical Characteristics of Coronavirus Disease 2019 in China Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis COVID-19: epidemiology, evolution, and crossdisciplinary perspectives Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19)-China Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China Coronavirus disease 2019 (COVID-19) in Italy Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease Severe outcomes among patients with coronavirus disease 2019 (COVID-19)-United States Preliminary estimates of the prevalence of selected underlying health conditions among patients with coronavirus disease 2019-United States Covid-19: risk factors for severe disease and death The gendered dimensions of COVID-19 COVID-19) time musings: Our involvement in COVID-19 pathogenesis, diagnosis, treatment and vaccine planning Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019-COVID-NET, 14 States Country Comparison :: Median age -The World Factbook -Central Intelligence Agency On the other hand, these surveys mainly deal with clinical characteristics of COVID-19 patients, in terms of related risk factors or underlying co-morbidities, whereas unsatisfactory information is provided regarding the therapeutic interventions adopted.
    keywords: cov-2; covid-19; disease; patients; sars
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        item: #2856 of 7819
          id: cord-287361-cpd4yl6c
      author: Ng, Qin Xiang
       title: The Wounded Healer: A Narrative Review of the Mental Health Effects of the COVID-19 Pandemic on Healthcare Workers
        date: 2020-06-20
       words: 980
      flesch: 46
     summary: The effects of social support on sleep quality of medical staff treating patients with coronavirus disease 2019 (COVID-19 Mental health and psychosocial problems of medical health workers during the COVID-19 epidemic in China. Asian J Psychiatr DOI: 10.1016/j.ajp.2020.102258 sha: doc_id: 287361 cord_uid: cpd4yl6c nan Health systems and healthcare workers worldwide are experiencing tremendous stress because of the growing Coronavirus Disease 2019 pandemic.
    keywords: covid-19; health; workers
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        item: #2857 of 7819
          id: cord-287376-wxldnlih
      author: Krüger, Colin M.
       title: Can surgery follow the dictates of the pandemic “keep your distance”? Requirements with COVID-19 for hygiene, resources and the team
        date: 2020-08-03
       words: 3982
      flesch: 41
     summary: Requirements with COVID-19 for hygiene, resources and the team date: 2020-08-03 journal: GMS Hyg Infect Control DOI: 10.3205/dgkh000354 sha: doc_id: 287376 cord_uid: wxldnlih Since the beginning of the pandemic, there have been restrictions in the daily care of surgical patients – both elective and emergency. Surgical patient care with reduced intensive care and inpatient bed capacity 4.
    keywords: aerosols; air; care; covid-19; operating; pandemic; patients; room; staff; surgery; team; ventilation
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        item: #2858 of 7819
          id: cord-287440-xy8o1mhs
      author: Caci, Barbara
       title: Neuroticism and Fear of COVID-19. The Interplay Between Boredom, Fantasy Engagement, and Perceived Control Over Time
        date: 2020-10-13
       words: 5210
      flesch: 39
     summary: The current study tested a moderate-mediation model seeking suggestions to reduce perceived fear of COVID-19, given the numerous pieces of evidence of the indirect impact of COVID-19 on the mental health of worldwide populations (Li et al., 2020) . Hypothesis 5 established the effect of the moderating role of perceived time control on the relationship between boredom and fear of COVID-19.
    keywords: boredom; control; covid-19; fantasy; fear; neuroticism; relationship; scale; time
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        item: #2859 of 7819
          id: cord-287444-vk3fdroq
      author: Quadri, Nasreen S.
       title: Deploying Medical Students to Combat Misinformation During the COVID-19 Pandemic
        date: 2020-06-02
       words: 416
      flesch: 29
     summary: We have an opportunity to close this gap in medical education and address the general public's need for guidance from the medical community about COVID-19 by engaging medical students as leaders in sharing knowledge about COVID-19 with the general public. Through this course, medical students learn about COVID-19 in a manner that facilitates rigorous evaluation of the evolving sources of information.
    keywords: students
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        item: #2860 of 7819
          id: cord-287452-nslygsdf
      author: Hamam, Asmaa Abu
       title: Peritraumatic reactions during the COVID-19 pandemic – The contribution of posttraumatic growth attributed to prior trauma
        date: 2020-09-30
       words: 7773
      flesch: 40
     summary: Addressing this gap, 528 Israeli trauma survivors were assessed for PTG and PTSD symptoms attributed to prior trauma, as well as peritraumatic stress symptoms related to the pandemic, as part of an online survey. The COVID-19 pandemic might be traumatogenic, leading to the development of peritraumatic stress symptoms.
    keywords: covid-19; et al; pandemic; peritraumatic; ptg; stress; stress symptoms; symptoms; trauma
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        item: #2861 of 7819
          id: cord-287459-k9x3z2h1
      author: Abu-Farha, Mohamed
       title: The Role of Lipid Metabolism in COVID-19 Virus Infection and as a Drug Target
        date: 2020-05-17
       words: 4839
      flesch: 36
     summary: The role lipids play in viral infection involves the fusion of the viral membrane to the host cell, viral replication, and viral endocytosis and exocytosis. Even though lipid-lowering capabilities might impact viral replication, statins can also help in mitigating the impact of viral infection through their immunomodulatory and anti-inflammatory properties [60] .
    keywords: cell; coronavirus; covid-19; host; infection; lipid; membrane; replication; role; sars; statins; virus
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        item: #2862 of 7819
          id: cord-287470-otsts5c9
      author: Kim, So Mi
       title: Perception and attitudes of medical students on clinical clerkship in the era of the Coronavirus Disease 2019 pandemic
        date: 2020-08-25
       words: 3693
      flesch: 39
     summary: In addition, given that medical students taking this survey were selected from one university and the number of participants was relatively small, the generalizability of these findings to other medical students in Korea is limited. key: cord-287470-otsts5c9 authors: Kim, So Mi; Park, Seok Gun; Jee, Young Koo; Song, Il Han title: Perception and attitudes of medical students on clinical clerkship in the era of the Coronavirus Disease 2019 pandemic date: 2020-08-25 journal: Medical education online DOI: 10.1080/10872981.2020.1809929 sha: doc_id: 287470 cord_uid: otsts5c9 BACKGROUND:
    keywords: clerkship; clerkship training; covid-19; medical; pandemic; students; training
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        item: #2863 of 7819
          id: cord-287497-93oiiqqi
      author: Tagliamento, Marco
       title: Italian survey on managing immune checkpoint inhibitors in oncology during COVID‐19 outbreak
        date: 2020-06-14
       words: 3231
      flesch: 40
     summary: Immunotherapy blockade on severity of COVID-19 in patients with lung cancers Outcome of cancer patients infected with COVID-19, including toxicity of cancer treatments Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study. Cancer patients have been reported to experience a more severe COVID‐19 syndrome; moreover, there are concerns of an interference between immune checkpoint inhibitors (ICIs) and SARS‐CoV‐2 pathogenesis.
    keywords: cancer; cov-2; covid-19; icis; patients; respondents; sars
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        item: #2864 of 7819
          id: cord-287505-ihqzpdar
      author: Narain, Sonali
       title: Comparative Survival Analysis of Immunomodulatory Therapy for COVID-19 'Cytokine Storm'
        date: 2020-10-17
       words: 3654
      flesch: 37
     summary: COVID-19 patients hospitalized between March 1, 2020 and April 24, 2020 were included. In the timeframe of this analysis, hydroxychloroquine, azithromycin, colchicine and vitamin C, either alone or in combination, were administered to COVID-19 patients as part of institutional protocols (Supplemental e-
    keywords: anakinra; corticosteroids; covid-19; disease; groups; mortality; patients; tocilizumab; treatment
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        item: #2865 of 7819
          id: cord-287507-1xb2hipt
      author: Rubio-San-Simón, A.
       title: Challenges in early phase clinical trials for childhood cancer during the COVID-19 pandemic: a report from the new agents group of the Spanish Society of Paediatric Haematology and Oncology (SEHOP)
        date: 2020-05-29
       words: 2285
      flesch: 43
     summary: Although there are multiple publications about generic emergency preparedness in health settings, there is minimal information focusing on clinical trial sites [16, 17] and we provide recommendations on this respect (Fig. 1) . The European Medicines Agency and the Spanish Agency of Medicines and Medical Devices have issued guidelines on the management of clinical trial activities [7, 8] Both are aligned in the intention to guarantee trial activity, patient safety, and action traceability.
    keywords: cancer; covid-19; impact; pandemic; patients; research; trials; units
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        item: #2866 of 7819
          id: cord-287508-133inel2
      author: Vasudevan, Rajiv S.
       title: Persistent Value of the Stethoscope in the Age of COVID-19
        date: 2020-06-19
       words: 3740
      flesch: 29
     summary: Stethoscopes are clinically valuable and integral to the doctor-patient connection; • Technological advancement will augment the utility of the stethoscope; • The stethoscope has high utility for assessment of COVID-19 patients; • Pathogen contamination in light of COVID-19 is a concern for the stethoscope; • Innovations in stethoscope hygiene will allow safe auscultation. Hand contamination, which has a clear connection to healthcare associated infections, is also an independent predictor of stethoscope contamination 26 .
    keywords: care; contamination; covid-19; healthcare; heart; hygiene; infection; patients; stethoscope; study
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        item: #2867 of 7819
          id: cord-287520-51kmd2ds
      author: Carneiro, Arie
       title: Impact of the COVID-19 Pandemic on the Urologist’s clinical practice in Brazil: a management guideline proposal for low- and middle-income countries during the crisis period
        date: 2020-05-20
       words: 4546
      flesch: 42
     summary: After the procedure, COVID-19 positive patients should be admitted to the designated areas for suspected and / or confirmed patients with COVID-19, if the institution in question provides such area. While efforts should be directed to the care of COVID-19 patients, other conditions (especially urgencies and oncological cases) must continue to be assisted.
    keywords: bladder; cancer; cases; chemotherapy; covid-19; pandemic; patients; prostate; risk; treatment; use
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        item: #2868 of 7819
          id: cord-287544-n32iscmr
      author: Solaimanzadeh, Isaac
       title: Nifedipine and Amlodipine Are Associated With Improved Mortality and Decreased Risk for Intubation and Mechanical Ventilation in Elderly Patients Hospitalized for COVID-19
        date: 2020-05-12
       words: 5449
      flesch: 37
     summary: CCB patients were also significantly less likely to undergo intubation and mechanical ventilation. CCB patients were also significantly less likely to undergo intubation and mechanical ventilation.
    keywords: amlodipine; ccb; covid-19; disease; group; hypertension; nifedipine; patients; treatment
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        item: #2869 of 7819
          id: cord-287607-d3k26aar
      author: Emamaullee, Juliet
       title: Rapid Adaptation of a Surgical Research Unit to Conduct Clinical Trials during the Coronavirus-19 Pandemic.
        date: 2020-06-29
       words: 3273
      flesch: 30
     summary: Ongoing ‘Stay at Home’ orders and institutional policies mandating ‘Work from Home’ for non-essential employees, which includes most research personnel, have impacted the ability to implement and conduct clinical studies. By centralizing the clinical trials process within the department and under the guidance of an experienced Chief and seasoned research team, the capacity for clinical studies has increased substantially while maintaining a stable number of study personnel (Figure 1) .
    keywords: covid-19; enrollment; research; studies; study; team; trials
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        item: #2870 of 7819
          id: cord-287625-dysdzjj1
      author: Siddaway, Andy P
       title: Multidisciplinary research priorities for the COVID-19 pandemic
        date: 2020-06-18
       words: 514
      flesch: 35
     summary: The extensive literatures on stress, adjustment, coping, and trauma can be drawn upon to maximise the impact of COVID-19 mental health research. However, it is crucial that researchers keep context in mind when determining the presence of mental health problems; endorsing COVID-19-related distress or psychiatric symp toms might not itself be enough to indicate psychological problems.
    keywords: covid-19; health
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        item: #2871 of 7819
          id: cord-287626-lnao60co
      author: Gaspar, R.
       title: Trends in cirrhosis hospitalizations during the COVID-19 pandemic
        date: 2020-07-15
       words: 839
      flesch: 33
     summary: We compared the trends in decompensated cirrhosis hospitalizations with those observed in the same period in the years 2015-2019 to account for the potential for residual confounding based on seasonal trends in decompensated cirrhosis hospitalizations. key: cord-287626-lnao60co authors: Gaspar, R.; Liberal, R.; Branco, Catarina Castelo; Macedo, G. title: Trends in cirrhosis hospitalizations during the COVID-19 pandemic date: 2020-07-15 journal: Dig Liver Dis DOI: 10.1016/j.dld.2020.06.044 sha: doc_id: 287626 cord_uid: lnao60co nan The emergence of the COVID-19 pandemic, which started in Wuhan in 2019 changed the world and created several challenges to healthcare services.
    keywords: cirrhosis; covid-19; hospitalizations
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        item: #2872 of 7819
          id: cord-287640-9j0w7191
      author: Ilesanmi, Olayinka
       title: Perception and practices during the COVID-19 pandemic in an urban community in Nigeria: a cross-sectional study
        date: 2020-09-23
       words: 4320
      flesch: 48
     summary: Findings from previous studies conducted in Nigeria also corroborate the key role of positive risk perception on imbibing COVID-19 protective practices and attitudes . The characteristic prevalence of COVID-19 infection among this group of persons accorded COVID-19 the name, 'a disease of the rich and mighty' (Nwaubani, 2020) .
    keywords: community; covid-19; handwashing; members; nigeria; perception; practices; respondents; study
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        item: #2873 of 7819
          id: cord-287644-ay0vv27m
      author: Blackall, Douglas
       title: Rapid Establishment of a COVID‐19 Convalescent Plasma Program in a Regional Healthcare Delivery Network
        date: 2020-08-04
       words: 3771
      flesch: 45
     summary: 7 Without a vaccine or effective medications to ameliorate COVID-19, the establishment of convalescent plasma transfusion programs has taken on greater urgency. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 Coronavirus disease 2019 (COVID-19) situation summary New cases of COVID-19 in world countries Current targeted therapeutics against COVID-19: based on first-line experience in China COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics Convalescent plasma: therapeutic hope or hopeless strategy in the SARS-CoV-2 pandemic Evaluation of convalescent plasma for Ebola virus disease in Guinea COVID-19 expanded access program Fair allocation of scarce medical resources in the time of Covid-19 Effectiveness of convalescent plasma therapy in severe COVID-19 patients Treatment of 5 critically ill patients with COVID-19 convalescent plasma COVID-19 convalescent plasma: now is the time for better science Antibody-dependent enhancement of severe dengue disease in humans Current studies of convalescent plasma therapy for COVID-19 may underestimate risk of antibody-dependent enhancement Viral-induced enhanced disease illness The authors acknowledge the outstanding contributions made by regional pharmacy staff for the recruitment of convalescent plasma donors, regional blood bank staff for processing and distributing convalescent plasma, information technology staff for developing the system to manage all aspects of the hospital transfusion process, and the staff at Mississippi Valley Regional Blood Center for rapidly implementing a system to collect convalescent plasma.
    keywords: article; ccp; convalescent; covid-19; patients; plasma; program; rights; transfusion
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        item: #2874 of 7819
          id: cord-287648-nhsn4cru
      author: Cameli, Matteo
       title: Usefulness of echocardiography to detect cardiac involvement in COVID‐19 patients
        date: 2020-07-12
       words: 3047
      flesch: 21
     summary: The left atrium and the right ventricle: two supporting chambers to the failing left ventricle Standardization of left atrial, right ventricular, and right atrial deformation imaging using two-dimensional speckle tracking echocardiography: a consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging ACUTE HF score, a multiparametric prognostic tool for acute heart failure: a real-life study Prognostic Value of Right Ventricular Longitudinal Strain in Patients with COVID-19 Echocardiography to guide fluid therapy in critically ill patients: check the heart and take a quick look at the lungs Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected Serial evaluation of the SOFA score to predict outcome in critically ill patients Prognostic impact of left ventricular diastolic function in patients with septic shock Early diastolic dysfunction is associated with intensive care unit mortality in cancer patients presenting with septic shock Outcome prediction in sepsis: speckle tracking echocardiography based assessment of myocardial function Left ventricular global longitudinal strain is independently associated with mortality in septic shock patients Effect of lung recruitment and titrated positive end-expiratory pressure (PEEP) vs low PEEP on mortality in patients with acute respiratory distress syndrome: a randomized clinical trial Clinical management of severe acute respiratory infection when novel coronavirus (2019-nCoV) infection is suspected: Interim guidance. Accordingly, current reports suggest that the majority of COVID-19 patients with myocardial injury without evidence of epicardial coronary artery thrombosis, show imaging data supporting the diagnosis of acute myocarditis 21, 22 ; also, cases of fulminant myocarditis and fatal arrhythmias have been described.
    keywords: acute; coronavirus; covid-19; disease; echocardiography; injury; myocarditis; patients; syndrome
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        item: #2875 of 7819
          id: cord-287653-69nfi379
      author: Lacy, J. Matthew
       title: COVID-19: POSTMORTEM DIAGNOSTIC AND BIOSAFETY CONSIDERATIONS
        date: 2020-04-24
       words: 5207
      flesch: 39
     summary: 10-13 A variety of electronic databases provide ongoing daily monitoring of COVID-19 cases tabulated by country. Currently every state in the U.S. has reported COVID-19 cases, resulting in a total of over 7600 deaths to date.
    keywords: autopsy; bag; body; cases; coronavirus; cov-2; covid-19; disease; isolation; ppe; sars; scene; testing; transmission
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        item: #2876 of 7819
          id: cord-287676-qh7zeyyx
      author: Angoulvant, François
       title: COVID-19 pandemic: Impact caused by school closure and national lockdown on pediatric visits and admissions for viral and non-viral infections, a time series analysis
        date: 2020-06-03
       words: 1815
      flesch: 44
     summary: M a n u s c r i p t Impact of lockdown on weekly pediatric emergency department visits and major pediatric infectious diseases, from January 1 st , 2017 to April 19 th , 2020. We hypothesized that this unusual situation in France would be associated with a sharp decrease in pediatric infectious diseases that usually disseminate through social contacts, with schools at their center.
    keywords: analysis; decrease; lockdown; visits
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        item: #2877 of 7819
          id: cord-287684-z3l9tsir
      author: Johnson, Sonia
       title: Impact on mental health care and on mental health service users of the COVID-19 pandemic: a mixed methods survey of UK mental health care staff
        date: 2020-08-28
       words: 6656
      flesch: 42
     summary: key: cord-287684-z3l9tsir authors: Johnson, Sonia; Dalton-Locke, Christian; Vera San Juan, Norha; Foye, Una; Oram, Sian; Papamichail, Alexandra; Landau, Sabine; Rowan Olive, Rachel; Jeynes, Tamar; Shah, Prisha; Sheridan Rains, Luke; Lloyd-Evans, Brynmor; Carr, Sarah; Killaspy, Helen; Gillard, Steve; Simpson, Alan title: Impact on mental health care and on mental health service users of the COVID-19 pandemic: a mixed methods survey of UK mental health care staff date: 2020-08-28 journal: The COVID-19 pandemic has potential to disrupt and burden the mental health care system, and to magnify inequalities experienced by mental health service users.
    keywords: care; community; covid-19; crisis; health; mental; pandemic; people; service; staff; table; users; working
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        item: #2878 of 7819
          id: cord-287721-qsx1eov0
      author: Berman, Adam E
       title: Elective cardiovascular care in the era of the COVID-19 pandemic: managing tragic choices
        date: 2020-09-28
       words: 2092
      flesch: 32
     summary: One example of this is the cancellation of 'elective' CV procedures. Given the broad discretion encompassed within the CMS tiered framework, some US health systems continued to proceed with elective CV procedures while others restricted them.
    keywords: covid-19; elective; pandemic; procedures
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        item: #2879 of 7819
          id: cord-287732-abzpfdcu
      author: Martindale, Robert
       title: Nutrition Therapy in Critically Ill Patients with Coronavirus Disease (COVID‐19)
        date: 2020-05-27
       words: 6234
      flesch: 37
     summary: Unless vasopressor dose is escalating and/or enteral feeding intolerance ensues (e.g. ileus, abdominal distention, vomiting), circulatory shock associated with SARS-CoV-2 should not be seen as a contraindication to trophic EN. 5 Early EN may not be preferred in a subset of COVID-19 patients with GI symptoms. Continuous postive pressure ventilation through helmet has been used exensively in Italy for COVID-19 patients, and nutition maybe provided more effectively and safely than mask NIPPV, but data are needed.
    keywords: article; care; copyright; covid-19; enteral; feeding; icu; nutrition; patients; recommendation; rights; risk; therapy
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        item: #2880 of 7819
          id: cord-287734-q7ae4dyf
      author: Brosnahan, Shari B.
       title: Thrombosis at Hospital Presentation in Patients with and without COVID-19
        date: 2020-11-10
       words: 2079
      flesch: 36
     summary: 17 We showed increased mortality in COVID-19 patients who develop outpatient thrombosis as Respiratory infections, and pneumonia specifically, have shown to increase incidence of venous 4 thromboembolism. key: cord-287734-q7ae4dyf authors: Brosnahan, Shari B.; Smilowitz, Nathaniel R.; Amoroso, Nancy E.; Barfield, Michael; Berger, Jeffery S.; Goldenberg, Ronald; Ishida, Koto; Talmor, Nina; Torres, Jose; Yaghi, Shadi; Yuriditsky, Eugene; Maldonado, Thomas title: Thrombosis at Hospital Presentation in Patients with and without COVID-19 date: 2020-11-10 journal: J Vasc Surg Venous Lymphat Disord DOI: 10.1016/j.jvsv.2020.11.004 sha: doc_id: 287734 cord_uid: q7ae4dyf OBJECTIVE: To better characterize COVID-19 patients most at risk for severe, outpatient thrombosis by defining patients hospitalized with COVID-19 with an arterial or venous thrombosis diagnosed at admission METHODS AND RESULTS:
    keywords: covid-19; hospital; mortality; patients; thrombosis
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        item: #2881 of 7819
          id: cord-287742-y1j9x5ne
      author: Lee, Kai Wei
       title: Stroke and Novel Coronavirus Infection in Humans: A Systematic Review and Meta-Analysis
        date: 2020-10-06
       words: 6552
      flesch: 38
     summary: Ischemic stroke was the predominant stroke, and it was observed in 90.3% of stroke cases as compared to 9.7% patients presenting with hemorrhagic stroke. The following data were extracted from every study: the last name of the first author, year of publication, country, severity status, study design, patient characteristics (ethnicity composition, gender, and mean age), comorbidities (diabetes, hyperlipidemia, hypertension, ischemic heart disease, heart failure, previous stroke, chronic kidney disease/end-stage renal disease, number of stroke patients per overall participants, any information relevant to strokes such as the location of stroke [arterial or venous]), types of stroke (ischemic or haemorrhagic), classification of stroke, mortality rate, and blood parameters.
    keywords: analysis; coronavirus; covid-19; data; disease; infection; ischemic; meta; patients; review; risk; stroke; studies
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        item: #2882 of 7819
          id: cord-287758-da11ypiy
      author: Mônica Vitalino de Almeida, Sinara
       title: COVID-19 therapy: what weapons do we bring into battle?
        date: 2020-09-10
       words: 17493
      flesch: 35
     summary: More preclinical and clinical studies are required to prove whether dasatinib is really promising for COVID-19 patient treatment. SBV is also combined with other antiviral drugs, such as ledipasvir, velpatasvir and voxilaprevir.
    keywords: action; activity; antiviral; binding; cells; clinical; coronavirus; cov-2; covid-19; disease; drug; entry; fig; host; human; infection; inhibitor; mechanism; new; novel; patients; potential; pro; protein; receptor; replication; results; rna; sars; studies; study; syndrome; synthesis; targets; therapy; treatment
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        item: #2883 of 7819
          id: cord-287776-ylui7ls8
      author: Murillo-Zamora, E.
       title: Male gender and kidney illness associated with an increased risk of severe laboratory-confirmed coronavirus disease
        date: 2020-07-01
       words: 2733
      flesch: 52
     summary: Among 414 subjects (non-severe disease, n = 306; severe disease, n = 108) in whom the use of antipyretic drugs was documented before healthcare seeking. . Among 414 subjects (non-severe disease, n = 306; severe disease, n = 108) in whom the use of antipyretic drugs was documented before healthcare seeking.
    keywords: covid-19; disease; license; medrxiv; patients; preprint
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        item: #2884 of 7819
          id: cord-287781-bvintr10
      author: Sakka, Mehdi
       title: Association between D-Dimer levels and mortality in patients with coronavirus disease 2019 (COVID-19): a systematic review and pooled analysis
        date: 2020-05-27
       words: 2502
      flesch: 37
     summary: Conclusions: Despite high heterogeneity across included studies, the present pooled analysis indicates that D-Dimer levels are significantly associated with the risk of mortality in COVID-19 patients. Early integration of D-Dimer testing, which is a rapid, inexpensive, and easily accessible biological test, can be useful to better risk stratification and management of COVID-19 patients.
    keywords: coronavirus; covid-19; dimer; levels; patients; studies; study
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        item: #2885 of 7819
          id: cord-287785-rs306oyq
      author: English, Mike
       title: Systems and implementation science should be part of the COVID-19 response in low resource settings
        date: 2020-07-15
       words: 1160
      flesch: 38
     summary: Over 60 LRS governments had applied for World Bank funding by 19th June 2020 with plans to spend huge sums on health system strengthening at unprecedented speed [1] . Ideally, we should take advantage of COVID-19 investments to transform health systems for the long term and ally this to rigorous systems and implementation research [6] .
    keywords: covid-19; health; research; systems
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        item: #2886 of 7819
          id: cord-287823-avi14ee5
      author: Wong, Martin CS
       title: The potential impact of vulnerability and coping capacity on the pandemic control of COVID-19
        date: 2020-05-28
       words: 1055
      flesch: 36
     summary: Hence, further exploration of the association between country capacity and COVID-19 burden is needed based on other indicators. ) The European commission has developed an index for risk management named INFORM; • Two dimensions (vulnerability and lack of coping capacity) are relevant to COVID-19; • We examined if these dimensions were associated with COVID-19 pandemic control; • Higher vulnerability and poorer coping capacity were associated with poorer control; • Modifying these two dimensions might potentially mitigate COVID-19 pandemic control. 
    keywords: covid-19; pandemic; vulnerability
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        item: #2887 of 7819
          id: cord-287872-i6cahnxd
      author: Wendt, F. R.
       title: Host genetic liability for severe COVID-19 overlaps with alcohol drinking behavior and diabetic outcomes and in over 1 million participants
        date: 2020-11-12
       words: 1605
      flesch: 34
     summary: Five phenotypes were significantly genetically correlated with severe respiratory COVID-19 after multiple testing correction and not correlated (unadjusted p-value >0.05) with hospitalized COVID-19 (Table S3 ) For two COVID-19 phenotypes with h 2 z-scores > 4, severe respiratory COVID-19 and hospitalized COVID-19, we then estimated their genetic correlation (rg) with 4,083 phenotypes from the UK Biobank (UKB, see http://www.nealelab.is/uk-biobank).
    keywords: causal; covid-19; diabetes; outcomes; phenotypes; preprint
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        item: #2888 of 7819
          id: cord-287874-wl0wlxh6
      author: Wang, Ling
       title: Quadruple therapy for asymptomatic COVID-19 infection patients
        date: 2020-05-03
       words: 5535
      flesch: 42
     summary: After large-scale interpersonal infection, asymptomatic patients appear. Whether asymptomatic patients are contagious or not and whether they need medication are the arguments among clinical experts.
    keywords: arbidol; asymptomatic; covid-19; drug; ifn; infection; lopinavir; patients; ritonavir; treatment; virus
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        item: #2889 of 7819
          id: cord-287875-jy9mzets
      author: Ambrosetti, Maria Chiara
       title: Rapid onset of bronchiectasis in COVID-19 Pneumonia: two cases studied with CT
        date: 2020-08-05
       words: 2381
      flesch: 42
     summary: CT findings of COVID-19 pulmonary infection are bilateral, peripheral and basal predominant ground-glass opacity, crazy-paving and consolidation, often with an extensive geographical distribution. Routine unenhanced chest CT is useful in early diagnosis of COVID-19 infection, in monitoring disease progression, coinfection, or disease stability 3 .
    keywords: bronchiectasis; covid-19; patients; pneumonia
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        item: #2890 of 7819
          id: cord-287918-hf9cyr16
      author: Smith, S.
       title: Impaired glucose metabolism in patients with diabetes, prediabetes and obesity is associated with severe Covid-19
        date: 2020-06-05
       words: 2875
      flesch: 51
     summary: One-sided hypothesis tests were used to determine if the proportions of Covid-19 patients with DM and PreDM were larger than the U.S. population proportions, and if the proportion of NonDM patients was smaller than the U.S. population proportion. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 Covid-19 in Critically Ill Patients in the Seattle Region -Case Series Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS COVID-19 and diabetes Clinical considerations for patients with diabetes in times of COVID-19 epidemic Diagnosis and Classification of Diabetes Mellitus CDC (2020) National Diabetes Statistics Report Obesity could shift severe COVID-19 disease to younger ages Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19 Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes Expression in Pancreas May Cause Pancreatic Damage After SARS-CoV-2
    keywords: covid-19; license; medrxiv; patients; preprint
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        item: #2891 of 7819
          id: cord-287949-243xlmep
      author: Onovo, A. A.
       title: Using Supervised Machine Learning and Empirical Bayesian Kriging to reveal Correlates and Patterns of COVID-19 Disease outbreak in sub-Saharan Africa: Exploratory Data Analysis
        date: 2020-05-02
       words: 4906
      flesch: 47
     summary: Our study indicates, the doubling time in new coronavirus cases was 3 days. The trend in new coronavirus cases appears to be doubling in South Africa at every time increment compared to the other countries demonstrating an exponential trend.
    keywords: cases; coronavirus; countries; covid-19; data; disease; license; preprint; ssa
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        item: #2892 of 7819
          id: cord-287957-diyz54qy
      author: Deriba, Berhanu Senbeta
       title: Patient Satisfaction and Associated Factors During COVID-19 Pandemic in North Shoa Health Care Facilities
        date: 2020-10-13
       words: 4257
      flesch: 40
     summary: Overall, 44.6% of patients with chronic disease were satisfied with the service they received from health facilities. Therefore, this study aimed to assess patient satisfaction and associated factors during the COVID-19 pandemic among chronic patients who had follow-up at public health facilities in the North Shoa Zone, Oromia region, Ethiopia.
    keywords: covid-19; data; disease; facilities; health; healthcare; hospital; participants; patient; satisfaction; study
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        item: #2893 of 7819
          id: cord-288017-f9b3t0ts
      author: Kabeerdoss, Jayakanthan
       title: Understanding immunopathological fallout of human coronavirus infections including COVID‐19: Will they cross the path of rheumatologists?
        date: 2020-08-10
       words: 4290
      flesch: 36
     summary: medRxiv Complex immune dysregulation in COVID-19 patients with severe respiratory failure Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study On the alert for cytokine storm: immunopathology in COVID-19 Potential effect of blood purification therapy in reducing cytokine storm as a late complication of critically ill COVID-19 Genomic analysis reveals age-dependent innate immune responses to severe acute respiratory syndrome coronavirus Exacerbated innate host response to SARS-CoV in aged non-human primates Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort Pediatric Kawasaki disease and adult human immunodeficiency virus Kawasaki-like syndrome are likely the same malady Coagulopathy and antiphospholipid antibodies in patients with Covid-19 Novel paediatric presentation of COVID-19 with ARDS and cytokine storm syndrome without respiratory symptoms Characteristics of ischaemic stroke associated with COVID-19 Lupus anticoagulant is frequent in patients with Covid-19 Lupus anticoagulant and abnormal coagulation tests in patients with Covid-19 Neutrophil extracellular traps in COVID-19 COVID-19 and aPL Ab -Hematology.org [Internet Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology Chloroquine attenuates TLR3/IFN-β signaling in cultured normal human mesangial cells: A possible protective effect against renal damage in lupus nephritis Poly(I:C) induces human lung endothelial barrier dysfunction by disrupting tight junction expression of claudin-5 Small molecules targeting the innate immune cGAS-STING-TBK1 signaling pathway Cutting edge: antimalarial drugs inhibit IFN-β production through blockade of cyclic GMP-AMP synthase-DNA interaction SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro Chloroquine is a potent inhibitor of SARS coronavirus infection and spread A pilot study of hydroxychloroquine in treatment of patients with moderate COVID-19. Injection of convalescent sera from SARS patients to rhesus macaques also causes lung injury with similar histopathological features as in human disease.
    keywords: cells; coronavirus; covid-19; disease; hcq; ifn; infection; patients; response; sars; type
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        item: #2894 of 7819
          id: cord-288020-vhtr3l0w
      author: Côté, Andréanne
       title: Early prediction of the risk of severe coronavirus disease 2019: A key step in therapeutic decision making
        date: 2020-08-15
       words: 1349
      flesch: 35
     summary: Development and validation of the HNC-LL score for predicting the severity of coronavirus disease 2019 Sociodemographic, clinical and laboratory factors on admission associated with COVID-19 mortality in hospitalized patients: a retrospective observational study Clinical Features Predicting Mortality Risk in Patients With Viral Pneumonia: the MuLBSTA Score Applicability of the CURB-65 pneumonia severity score for outpatient treatment of COVID-19 Comparison of CRB-65 and quick sepsis-related organ failure assessment for predicting the need for intensive respiratory or vasopressor support in patients with COVID-19 Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City Area Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia COVID-19: consider cytokine storm syndromes and immunosuppression Effect of dexamethasone in hospitalized patients with COVID-19: Previous studies have reported that an important proportion (>20%) of hospitalized patients with COVID-19 present with a marked elevation of circulating biomarkers of inflammation (CRP, Ferritin), cardiovascular damage (Troponin) and thrombo-embolism (D-Dimers), identifying subgroups of patients at high risk of in-hospital morbidity and mortality
    keywords: disease; patients; risk; score
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        item: #2895 of 7819
          id: cord-288025-skkpkqw6
      author: Eslami, Hadi
       title: The role of environmental factors to transmission of SARS-CoV-2 (COVID-19)
        date: 2020-05-15
       words: 4862
      flesch: 45
     summary: Studies show that SARS-CoV-2 stays for more than 9 days and be resistant, like other coronaviruses such as SARS and Middle East Respiratory Syndrome (MERS), can live on inanimate surfaces such as metals, glass, and plastic at room temperature. Its results show that with a 1 °C increase of the minimum ambient air temperature, the cumulative number of cases decreases by 0.86% ( Fig. 1 ) (Wang et al. 2020b ).
    keywords: air; coronavirus; cov-2; covid-19; et al; food; sars; surfaces; transmission; virus
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        item: #2896 of 7819
          id: cord-288030-69e8cmy2
      author: Ardakani, Ali Abbasian
       title: Application of deep learning technique to manage COVID-19 in routine clinical practice using CT images: Results of 10 convolutional neural networks
        date: 2020-04-30
       words: 3435
      flesch: 47
     summary: This method was applied on lung CT images by Sun et al. to detect and differentiate nodules from the vessels. key: cord-288030-69e8cmy2 authors: Ardakani, Ali Abbasian; Kanafi, Alireza Rajabzadeh; Acharya, U. Rajendra; Khadem, Nazanin; Mohammadi, Afshin title: Application of deep learning technique to manage COVID-19 in routine clinical practice using CT images: Results of 10 convolutional neural networks date: 2020-04-30 journal: Comput Biol Med DOI: 10.1016/j.compbiomed.2020.103795 sha: doc_id: 288030 cord_uid: 69e8cmy2 Fast diagnostic methods can control and prevent the spread of pandemic diseases like coronavirus disease 2019 (COVID-19) and assist physicians to better manage patients in high workload conditions.
    keywords: covid-19; deep; layers; lung; network; patients; radiologists; study
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        item: #2897 of 7819
          id: cord-288038-jdinf8od
      author: Thindwa, Deus
       title: Use of seasonal influenza and pneumococcal polysaccharide vaccines in older adults to reduce COVID-19 mortality
        date: 2020-06-19
       words: 2617
      flesch: 31
     summary: Two vaccines that target a large burden of the remaining respiratory disease in older adults are seasonal influenza vaccines and 23-valent pneumococcal polysaccharide vaccine (PPV23). We conducted a non-systematic review of the published, pre-print and grey literature to evaluate whether vaccination of older adults with seasonal influenza vaccine or PPV23 could help reduce COVID-19 mortality.
    keywords: adults; covid-19; disease; influenza; risk; vaccine
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        item: #2898 of 7819
          id: cord-288051-wp8v2mc5
      author: Sánchez-González, Álvaro
       title: What Should Be Known by a Urologist About the Medical Management of COVID-19’s Patients?
        date: 2020-09-01
       words: 3624
      flesch: 45
     summary: The infection and isolation of many physicians reduced its availability to struggle against COVID-19, so it became essential to recruit surgical staff to assist COVID-19 patients. A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Pharmacologic treatments for coronavirus disease 2019 (COVID-19) a review COVID-19) outbreak: what the department of radiology should know Compassionate use of remdesivir for patients with severe Covid-19 Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial Effective treatment of severe COVID-19 patients with tocilizumab Why tocilizumab could be an effective treatment for severe COVID -19 ?
    keywords: coronavirus; cov-2; covid-19; days; disease; fig; infection; management; patients; sars; treatment
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        item: #2899 of 7819
          id: cord-288066-sh6n2c3n
      author: Mohamed, Mohamed S.
       title: Sex differences in COVID-19: the role of androgens in disease severity and progression
        date: 2020-11-11
       words: 2495
      flesch: 35
     summary: Androgen receptors are transcription promoters for TMPRSS2 and can, therefore, facilitate SARS-COV2 entry. The interaction between these genes juxtaposes the androgen receptor elements present in their code, causing the ERG gene to be also controlled by androgen receptor signalling [9] .
    keywords: androgen; cov2; covid-19; levels; receptor; sars; sensitivity
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        item: #2900 of 7819
          id: cord-288067-36amafub
      author: Ashraf, Mohammad Ali
       title: COVID-19 in Iran, a comprehensive investigation from exposure to treatment outcomes
        date: 2020-04-24
       words: 4375
      flesch: 53
     summary: [6] [7] [8] [9] This study is one of the first reports of COVID-19 patients from Iran. We presented the first 100 cases of COVID-19 patients in Tehran.
    keywords: covid-19; discharge; disease; hospital; medrxiv; patients; preprint; review; score
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        item: #2901 of 7819
          id: cord-288068-egq3d0i9
      author: Brown, Teneille R
       title: When The Wrong People Are Immune
        date: 2020-05-08
       words: 4510
      flesch: 48
     summary: For examples specifically targeted at providing physicians immunity in response to a pandemic, we can also look to laws in effect in Maryland and New York. While they are intimately involved in its mitigation, these heroic efforts should not expose them to unnecessary malpractice liability, merely because government immunity makes them the last target standing.
    keywords: care; covid-19; decisions; health; immunity; liability; pandemic; physicians; response; state
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        item: #2902 of 7819
          id: cord-288070-qwax5tg9
      author: Robilotti, E. V.
       title: Determinants of Severity in Cancer Patients with COVID-19 Illness
        date: 2020-05-08
       words: 2656
      flesch: 41
     summary: In this study, we report on the epidemiology of COVID-19 illness experienced at our cancer center over the last month, during the height of incident cases in New York City, and offer an analysis of risk factors for severe infection that is pertinent to cancer patient populations. Overall, 40% out of 423 patients with cancer were hospitalized for COVID-19 illness, 20% developed severe respiratory illness, including 9% that required mechanical ventilation, and 9% that died.
    keywords: cancer; covid-19; disease; illness; medrxiv; patients; preprint
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        item: #2903 of 7819
          id: cord-288080-rr9e61ay
      author: Mohadab, Mohamed El
       title: Bibliometric method for mapping the state of the art of scientific production in Covid-19
        date: 2020-06-30
       words: 2864
      flesch: 44
     summary: So the use of bibliometric analysis [2] to identify and analyze the scientific performance of authors, articles, journals, institutions, countries through the analysis of keywords and the number of citations constitutes an essential element which provides researchers with the means to identify avenues and new directions in relation to a theme of scientific research. Through bibliometric analyzes we try to get the trends of scientific research in the theme of Covid-19.
    keywords: analysis; cluster; covid-19; items; research
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        item: #2904 of 7819
          id: cord-288092-x3fdxnbr
      author: Fonseca, Mario
       title: Acute Exacerbation of Interstitial Lung Disease as a Sequela of COVID-19 Pneumonia
        date: 2020-08-11
       words: 1691
      flesch: 35
     summary: A close follow up of these patients after recovery from the acute event, with repeated pulmonary function The diagnosis and management of interstitial lung diseases Idiopathic pulmonary fibrosis Acute exacerbations of idiopathic pulmonary fibrosis: shifting the paradigm Viral infection in acute exacerbation of idiopathic pulmonary fibrosis WHO Declares COVID-19 a Pandemic The lung in rheumatoid arthritis: Focus on interstitial lung disease Sex-based differences in interstitial lung disease Rheumatoid arthritis and lung disease: from mechanisms to a practical approach Patients with interstitial lung disease and pulmonary sarcoidosis are at high risk for severe illness related to COVID-19 Practical Considerations for the Diagnosis and Treatment of Fibrotic Interstitial Lung Disease During the COVID-19 Pandemic Respiratory viral infections in chronic lung diseases Acute exacerbations complicating interstitial lung disease Pulmonary pathology of severe acute respiratory syndrome in Toronto COVID-19 and Acute Lupus Pneumonitis: Diagnostic and Treatment Dilemma Efficacy and safety of corticosteroids in COVID-19 based on evidence for COVID-19, other Coronavirus infections, influenza, community-acquired pneumonia and acute respiratory distress syndrome: A systematic review and meta-analysis Clinical features of rheumatic patients infected with COVID-19 in Wuhan COVID-19 and the heart The intersection of aging biology and the pathobiology of lung diseases: A joint NHLBI/NIA workshop Age-related rhesus macaque models of COVID-19 Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy INBUILD Trial Investigators. However, we do not know if coexistent connective tissue disorders like rheumatoid arthritis result in worse prognosis, especially in COVID-19 patients requiring hospitalization.
    keywords: covid-19; disease; ild; interstitial; lung
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        item: #2905 of 7819
          id: cord-288102-iom6lu7o
      author: Han, Jing
       title: Analysis of factors affecting the prognosis of COVID-19 patients and viral shedding duration
        date: 2020-06-25
       words: 4293
      flesch: 47
     summary: Severe patients were treated with lopinavir or ritonavir. One of the limitations of this study is that we assessed patients for only a limited time when they were hospitalised; thus, a longer follow-up period might be needed to further assess the prognosis of and viral shedding in cured COVID-19 patients.
    keywords: covid-19; duration; patients; prognosis; shedding; study; time; treatment
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        item: #2906 of 7819
          id: cord-288130-efffulhk
      author: Herrera, Miguel A Rubio
       title: Obesidad en tiempos de covid-19. Un desafío de salud global
        date: 2020-10-21
       words: 3529
      flesch: 26
     summary: Pese a que las frecuencias de obesidad de los pacientes analizados son inferiores a la prevalencia de la población española, se constata nuevamente que los pacientes ingresados con obesidad tienen mayor riesgo de complicaciones y de mortalidad. A pesar de las limitaciones de los estudios retrospectivos, de la insuficiente información sobre las características fenotípica de la obesidad, contamos con suficientes datos para sugerir que la obesidad comporta un factor de riesgo independiente de infección por la COVID-19, con mayor probabilidad de gravedad y mortalidad.
    keywords: como; con; covid-19; datos; del; infección; las; los; mayor; mortalidad; más; obesidad; obesity; pacientes; patients; personas; por; que; riesgo; risk; una
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        item: #2907 of 7819
          id: cord-288139-nq85fqux
      author: Tabish, Hilary B.
       title: Back to the basics: Hand washing is public health 101 and it works to slow down the spread of viruses
        date: 2020-09-03
       words: 1327
      flesch: 46
     summary: key: cord-288139-nq85fqux authors: Tabish, Hilary B.; Basch, Corey H. title: Back to the basics: Hand washing is public health 101 and it works to slow down the spread of viruses date: 2020-09-03 journal: Infect Dis Health DOI: 10.1016/ Although this novel virus requires innovation in balancing control measures to maximize safety while protecting livelihoods, there is tremendous value in relying on proven strategies and `getting back to public health basics,’ such as hand washing.
    keywords: hand; health; washing
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        item: #2908 of 7819
          id: cord-288174-w7rw9bej
      author: Shirai, Tsuyoshi
       title: COVID-19 pneumonia complicated by bilateral pneumothorax: a case report
        date: 2020-09-24
       words: 388
      flesch: 43
     summary: key: cord-288174-w7rw9bej authors: Shirai, Tsuyoshi; Mitsumura, Takahiro; Aoyagi, Kei; Okamoto, Tsukasa; Kimura, Moe; Gemma, Taku; Shigematsu, Takaaki; Takahashi, Junichi; Azuma, Seishin; Yoshizuka, Riku; Sasaki, Hirokazu; Urushibata, Nao; Ochiai, Kanae; Hondo, Kenichi; Morishita, Koji; Aiboshi, Junichi; Otomo, Yasuhiro; Miyazaki, Yasunari title: COVID-19 pneumonia complicated by bilateral pneumothorax: a case report date: 2020-09-24 journal: Respir Med Case Rep DOI: 10.1016/j.rmcr.2020.101230 sha: doc_id: 288174 cord_uid: w7rw9bej BACKGROUND: As several cases have been reported, pneumothorax is a 106 rare but lif e-threatening complication of COVID-19 pneumonia
    keywords: covid-19; pneumonia
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        item: #2909 of 7819
          id: cord-288184-fa1niz51
      author: Kwon, Chan-Young
       title: Using Mind–Body Modalities via Telemedicine during the COVID-19 Crisis: Cases in the Republic of Korea
        date: 2020-06-22
       words: 5697
      flesch: 50
     summary: Fourth, mental health telemedicine interventions for front-line healthcare providers also need to be developed. First, the impact of the pandemic on mental health started with the ambiguity and anxiety that arose from the absence of a cure or vaccine for SARS-CoV-2 infection, and the rapid spread of infection brought panic to the public with limited quarantine resources [8] .
    keywords: anxiety; body; covid-19; health; manual; meditation; mindfulness; patients; telemedicine
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        item: #2910 of 7819
          id: cord-288195-3lcs77uf
      author: Bilal, Mohammad
       title: What constitutes urgent endoscopy? A social media snapshot of gastroenterologists’ views during the COVID-19 pandemic
        date: 2020-04-17
       words: 3271
      flesch: 39
     summary: Semi-urgent endoscopy was defined as a procedure that could reasonably be deferred for at least 8 weeks without negatively-impacting an important patient outcome (e. g. upstaging of a new cancer diagnosis). In addition, the COVID-19 pandemic is in different phases throughout the world and as the crisis worsens, the definition of semi-urgent endoscopy may narrow.
    keywords: endoscopic; gastroenterologists; pandemic; patients; survey; urgent
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        item: #2911 of 7819
          id: cord-288197-drto66xt
      author: Chen, Huijun
       title: Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records
        date: 2020-02-12
       words: 3939
      flesch: 51
     summary: Considering that SARS-CoV-2 has up to 85% sequence similarity with SARS, [11] [12] [13] [14] although none of our patients developed severe pneumonia or died of COVID-19 infection, we should be alert to the possibility that the disease course and prognosis of COVID-19 pneumonia could follow the same trend as SARS in pregnant women. Answers to these questions are essential for formulating the principles of obstetric treatment for pregnant women with COVID-19 infection.
    keywords: clinical; covid-19; infection; patients; pneumonia; samples; sars; women
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        item: #2912 of 7819
          id: cord-288255-p8uzrsbd
      author: Goossens, Gijs H.
       title: Obesity and COVID-19: A Perspective from the European Association for the Study of Obesity on Immunological Perturbations, Therapeutic Challenges, and Opportunities in Obesity
        date: 2020-08-13
       words: 7056
      flesch: 32
     summary: COVID-19: consider cytokine storm syndromes and immunosuppression Validation of predictors of disease severity and outcomes in COVID-19 patients: a descriptive and retrospective study APOE e4 genotype predicts severe COVID-19 in the UK Biobank community cohort Apolipoprotein E -a multifunctional protein with implications in various pathologies as a result of its structural features Possible involvement of the adipose tissue renin-angiotensin system in the pathophysiology of obesity and obesity-related disorders Angiotensin II receptors and angiotensin II receptor antagonists Physiology and pathophysiology of the adipose tissue renin-angiotensin system The renin-angiotensin system in the pathophysiology of type 2 diabetes Role of the renin-angiotensin-aldosterone system and proinflammatory mediators in cardiovascular disease Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: Celebrating the 20th Anniversary of the Discovery of ACE2 Newly recognized components of the renin-angiotensin system: potential roles in cardiovascular and renal regulation Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor A pneumonia outbreak associated with a new coronavirus of probable bat origin Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. In COVID-19 patients, elevated plasma concentrations of both proinflammatory Th1 and anti-inflammatory Th2 cytokines were found [3] .
    keywords: adipose; angiotensin; coronavirus; cov-2; covid-19; disease; immune; infection; obesity; patients; people; risk; sars; tissue; treatment
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        item: #2913 of 7819
          id: cord-288264-xs08g2cy
      author: Ulahannan, Jijo Pulickiyil
       title: A citizen science initiative for open data and visualization of COVID-19 outbreak in Kerala, India
        date: 2020-08-06
       words: 3126
      flesch: 37
     summary: key: cord-288264-xs08g2cy authors: Ulahannan, Jijo Pulickiyil; Narayanan, Nikhil; Thalhath, Nishad; Prabhakaran, Prem; Chaliyeduth, Sreekanth; Suresh, Sooraj P; Mohammed, Musfir; Rajeevan, E; Joseph, Sindhu; Balakrishnan, Akhil; Uthaman, Jeevan; Karingamadathil, Manoj; Thomas, Sunil Thonikkuzhiyil; Sureshkumar, Unnikrishnan; Balan, Shabeesh; Vellichirammal, Neetha Nanoth title: A citizen science initiative for open data and visualization of COVID-19 outbreak in Kerala, India date: 2020-08-06 journal: J Am Med Inform Assoc DOI: 10.1093/jamia/ocaa203 sha: doc_id: 288264 cord_uid: xs08g2cy OBJECTIVE: MATERIALS AND METHODS: Through a citizen science initiative, we leveraged publicly available and crowd-verified data on COVID-19 outbreak in Kerala from the government bulletins and media outlets to generate reusable datasets.
    keywords: cases; covid-19; data; dataset; india; individuals; kerala; outbreak; public
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        item: #2914 of 7819
          id: cord-288271-p074ffpt
      author: Mathies, D.
       title: A Case of SARS‐CoV‐2‐pneumonia with successful antiviral therapy in a 77‐year‐old male with heart transplant
        date: 2020-04-21
       words: 2485
      flesch: 46
     summary: key: cord-288271-p074ffpt authors: Mathies, D.; Rauschning, D.; Wagner, U.; Mueller, F.; Maibaum, M.; Binnemann, C.; Waldeck, S.; Thinnes, K.; Braun, M.; Schmidbauer, W.; Hagen, RM.; Bickel, C. title: A Case of SARS‐CoV‐2‐pneumonia with successful antiviral therapy in a 77‐year‐old male with heart transplant date: 2020-04-21 journal: Am J Transplant DOI: 10.1111/ajt.15932 sha: doc_id: 288271 cord_uid: p074ffpt The SARS‐CoV‐2‐infection can be seen as a single disease but also affects patients with relevant comorbidities who may have an increased risk of a severe course of infection. Only a fistful of cases of a SARS-CoV 2-Infection in patients who received a solid organ transplant has been published so far [9, 10] .
    keywords: days; medication; patient; sars; therapy; transplant
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        item: #2915 of 7819
          id: cord-288304-80bn2wgd
      author: Sun, Y.
       title: The effect of non-pharmaceutical interventions (NPIs) on the spread of COVID-19 pandemic in Japan: A modeling study
        date: 2020-05-23
       words: 2733
      flesch: 51
     summary: We developed an SIRD model to estimate the peak number of existing infected COVID-19 cases, the peak date, and the ܴ in different periods. Using the SIRD model, we calculated the peak number of existing infected cases and the peak date.
    keywords: cases; covid-19; number; peak; period
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        item: #2916 of 7819
          id: cord-288307-6dlw2klz
      author: Fisher, Bryant
       title: The importance of repeat testing in detecting coronavirus disease 2019 (COVID‐19) in a coronary artery bypass grafting patient
        date: 2020-05-12
       words: 755
      flesch: 39
     summary: One study found that nearly 25% of COVID-19 positive individuals were negative on their initial testing with some testing positive after their third or fourth repeat test. In this case, the patient was exposed to COVID-19 positive individuals at her skilled nursing facility.
    keywords: covid-19; testing
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        item: #2917 of 7819
          id: cord-288311-8kcturbn
      author: Fassihi, Safa C.
       title: Novel Approach for Low‐Dose Pulmonary Delivery of Hydroxychloroquine in COVID‐19
        date: 2020-06-19
       words: 1536
      flesch: 36
     summary: Although further evidence is needed to determine the efficacy of aerosolized HCQ in the treatment of COVID-19, low-dose targeted pulmonary delivery represents a safe and potentially preferred delivery method, particularly given the purported mechanisms by which HCQ acts against SARS-CoV-2. After reviewing the prior literature, Klimke et al. tested the safety and tolerability of inhaled HCQ in two healthy human subjects by dissolving HCQ in 0.9% sodium chloride and administering it via commercial nebulizers.
    keywords: covid-19; hcq; hydroxychloroquine
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        item: #2918 of 7819
          id: cord-288331-n0n69axw
      author: Ozturk, Ayse Bilge
       title: Change in Allergy Practice during the COVID-19 Pandemic
        date: 2020-10-15
       words: 1945
      flesch: 36
     summary: Thirty-four percent of the physicians reported interruption of systemic steroid use in asthma patients, and 25% of the respondents discontinued biological therapy. Thirty-four percent of the physicians reported interruption of systemic steroid use in asthma patients.
    keywords: allergy; asthma; covid-19; pandemic; patients
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        item: #2919 of 7819
          id: cord-288336-io1t141z
      author: Singh, Rahul
       title: Case of Hemorrhagic Cardiac Tamponade in a Patient with COVID-19 Infection
        date: 2020-06-04
       words: 1065
      flesch: 40
     summary: key: cord-288336-io1t141z authors: Singh, Rahul; Fuentes, Stephanie; Ellison, Henry; Chavez, Miguel; Hadidi, Omar F.; Khoshnevis, Gholamreza; Chang, Su Min title: Case of Hemorrhagic Cardiac Tamponade in a Patient with COVID-19 Infection date: 2020-06-04 journal: CASE (Phila) DOI: 10.1016/j.case.2020.05.020 sha: doc_id: 288336 cord_uid: io1t141z • There are protean manifestations of cardiac involvement with COVID 19; • Hemorrhagic pericardial effusion may be the sole cardiac manifestation of COVID 19. However, other common causes of hemorrhagic pericardial effusion were highly unlikely 1,2 .
    keywords: cardiac; covid; effusion; tamponade
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        item: #2920 of 7819
          id: cord-288366-xe3pxrhv
      author: Wellbelove, Zoe
       title: Comparing the 4C mortality score for COVID-19 to established scores (CURB65, CRB65, qSOFA, NEWS) for respiratory infection patients
        date: 2020-10-25
       words: 684
      flesch: 31
     summary: key: cord-288366-xe3pxrhv authors: Wellbelove, Zoe; Walsh, Chloe; Perinpanathan, Tanaraj; Lillie, Patrick; Barlow, Gavin title: Comparing the 4C mortality score for COVID-19 to established scores (CURB65, CRB65, qSOFA, NEWS) for respiratory infection patients date: 2020-10-25 journal: J Infect DOI: 10.1016/j.jinf.2020.10.015 sha: doc_id: 288366 cord_uid: xe3pxrhv nan Comparing the 4C mortality score for COVID-19 to established scores (CURB65, CRB65, qSOFA, NEWS) for respiratory infection patients We have taken great interest in Ying et al's comparison of CRB-65 and qSOFA for predicting intensive respiratory support in COVID-19 patients. This supports the findings of Knight et al 2 , which showed that the 4C mortality score outperformed existing scores in COVID-19 patients.
    keywords: mortality; score
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        item: #2921 of 7819
          id: cord-288371-uyj4iske
      author: Arrieta, Oscar
       title: Recommendations for detection, prioritization, and treatment of thoracic oncology patients during the COVID‐19 pandemic: The THOCOoP cooperative group
        date: 2020-06-20
       words: 6676
      flesch: 36
     summary: patients with advanced non-small-cell lung cancer and poor performance status Metronomic oral vinorelbine as first-line treatment in elderly patients with advanced non-small cell lung cancer: results of a phase II trial (MOVE trial) Telemedicine for cancer patients during COVID-19 pandemic: between threats and opportunities Hyperprogressive Disease in Patients With Advanced Non-Small Cell Lung Cancer Treated With PD-1/PD-L1 Inhibitors or With Single-Agent Chemotherapy Immune-related adverse events with immune checkpoint inhibitors in thoracic malignancies: focusing on non-small cell lung cancer patients Characteristics and outcomes of small cell lung cancer patients diagnosed during two lung cancer computed tomographic screening programs in heavy smokers American College of Chest Physicians evidence-based clinical practice guidelines A Meta-Analysis of Thoracic Radiotherapy for Small-Cell Lung Cancer Systematic review evaluating the timing of thoracic radiation therapy in combined modality therapy for limited-stage small-cell lung cancer Time between the first day of chemotherapy and the last day of chest radiation is the most important predictor of survival in limited-disease small-cell lung cancer Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission Carboplatin-or cisplatin-based chemotherapy in first-line treatment of small-cell lung cancer: the COCIS meta-analysis of individual patient data First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer Role of thoracic consolidation radiation in extensive stage small cell lung cancer: Relevant information has emerged regarding the higher risk of poor outcomes in lung cancer patients.
    keywords: cancer; cell; chemotherapy; clinical; covid-19; disease; lung; mesothelioma; non; pandemic; patients; phase; recommendation; treatment
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        item: #2922 of 7819
          id: cord-288394-h9hozu9j
      author: Kheirallah, Khalid A.
       title: The Effect of Strict State Measures on the Epidemiologic Curve of COVID-19 Infection in the Context of a Developing Country: A Simulation from Jordan
        date: 2020-09-08
       words: 4942
      flesch: 45
     summary: Our results suggest that swift, intensive, and targeted lockdowns in Jordan may have caused new COVID-19 cases to plummet and the health system to be With COVID-19 imposing global public health and socioeconomic uncertainties, governments are counting on their people to adapt to NPIs in an effort to reduce the impact of the epidemic. Our results suggest that swift, intensive, and targeted lockdowns in Jordan may have caused new COVID-19 cases to plummet and the health system to be protected.
    keywords: cases; covid-19; covid-19 cases; epidemic; jordan; model; number
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        item: #2923 of 7819
          id: cord-288403-m6qe57he
      author: Abbas, K. M.
       title: Benefit-risk analysis of health benefits of routine childhood immunisation against the excess risk of SARS-CoV-2 infections during the Covid-19 pandemic in Africa
        date: 2020-05-26
       words: 7121
      flesch: 45
     summary: key: cord-288403-m6qe57he authors: Abbas, K. M.; Procter, S. R.; van Zandvoort, K.; Clark, A.; Funk, S.; LSHTM CMMID Covid-19 Working Group,; Mengistu, T.; Hogan, D.; Dansereau, E.; Jit, M.; Flasche, S. title: Benefit-risk analysis of health benefits of routine childhood immunisation against the excess risk of SARS-CoV-2 infections during the Covid-19 pandemic in Africa date: 2020-05-26 journal: nan DOI: 10.1101/2020.05.19.20106278 sha: doc_id: 288403 cord_uid: m6qe57he Background: National immunisation programmes globally are at risk of suspension due to the severe health system constraints and physical distancing measures in place to mitigate the ongoing COVID-19 pandemic. Our aim is to compare the health benefits of sustaining routine childhood immunisation in Africa against the risk of acquiring SARS-CoV-2 infections through visiting routine vaccination service delivery points.
    keywords: childhood; children; covid-19; deaths; immunisation; license; preprint; risk; routine; sars; vaccination
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        item: #2924 of 7819
          id: cord-288421-sgzg7ndp
      author: Grobler, Corlia
       title: Covid-19: The Rollercoaster of Fibrin(Ogen), D-Dimer, Von Willebrand Factor, P-Selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes
        date: 2020-07-21
       words: 10531
      flesch: 39
     summary: Heparin interferes with VWF platelet activation, and possibly assists in the prevention of thrombotic events. Fibrinogen, D-dimer, VWF and P-selectin are central in the development of coagulopathies, and coagulopathies with diverse aetiologies have been described in COVID-19 patients.
    keywords: activation; adhesion; binding; blood; cells; covid-19; dimer; endothelial; fibrinogen; integrin; levels; patients; platelet; selectin; signalling; vwf
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        item: #2925 of 7819
          id: cord-288443-f11r6zup
      author: Bowman, Ryan
       title: Surge after the surge: Anticipating the increased volume and needs of patients with head and neck cancer after the peak in COVID‐19
        date: 2020-05-16
       words: 1538
      flesch: 50
     summary: Patients with head and neck cancer are a particularly susceptible population to these effects, and we expect there to be a potential surge in patients presenting with head and neck cancers after the surge in COVID‐19. 1,2 COVID-19 has already had extraordinary effects on how multidisciplinary head and neck cancer (HNC) teams provide HNC patients in initial hotspots such as Wuhan, China and in Italy as well as the United States and throughout the world.
    keywords: covid-19; head; neck; patients
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        item: #2926 of 7819
          id: cord-288485-m3g88fl2
      author: Lam, Katherine W
       title: Continued In-Hospital Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use in Hypertensive COVID-19 Patients Is Associated With Positive Clinical Outcome
        date: 2020-07-23
       words: 3720
      flesch: 39
     summary: Several clinical studies have reported that ACEi/ARB use in COVID-19 patients with hypertension does not worsen COVID-19 disease severity or mortality Li et al accounted for inpatient use of ACEi/ARBs in COVID-19 patients, defining ACEi/ARB use as use of the medications at admission and continued throughout hospitalization [20] .
    keywords: acei; angiotensin; arb; arbs; covid-19; patients
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        item: #2927 of 7819
          id: cord-288490-l40t76la
      author: Omboni, Stefano
       title: Telemedicine During the COVID-19 in Italy: A Missed Opportunity?
        date: 2020-08-01
       words: 1267
      flesch: 40
     summary: This COVID-19 epidemic should help promote better use and a larger integration of telemedicine services in the armamentarium of health care services. We need to fully enact a transition to a more modern model of care, which must mandatorily envisage the full integration of telemedicine services and solutions in the armamentarium of health care services.
    keywords: health; patients; telemedicine
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        item: #2928 of 7819
          id: cord-288493-i15rb8d2
      author: Rother, N.
       title: Hydroxychloroquine inhibits trained immunity - implications for COVID-19
        date: 2020-06-09
       words: 7283
      flesch: 50
     summary: The majority of COVID-19 patients have mild symptoms, but some develop severe pneumonia 1 . This is exemplified by the fact that in COVID-19 patients a decreased type I interferon (IFN) response is observed, which is associated with impaired viral clearance 3, 4 .
    keywords: cells; covid-19; data; fig; hkca; hydroxychloroquine; immunity; june; license; medrxiv; monocytes; patients; perpetuity; preprint; version
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        item: #2929 of 7819
          id: cord-288500-ko4eda9w
      author: Zheng, Ruijun
       title: Prevalence and associated factors of depression and anxiety among nurses during the outbreak of COVID-19 in China: A cross-sectional study
        date: 2020-10-23
       words: 4693
      flesch: 43
     summary: However, the rate of depression among nurses who cared for the patients was almost the same as Lai et al study (Lai et al., 2020) , and higher than that of nurses caring for SARS patients in China (Lung et al., 2009; Su et al., 2007; Chen et al., 2005; Nickell et al., 2004; Lin et al., 2007) . Most of the previous studies (Chan et al., 2005; Chong et al., 2004; Lung et al., 2009; Su et al., 2007; Chen et al., 2005; Lin et al., 2007 ) had focused on nurses mental health at the mid-stage and final-stage of SARS pandemic, comparing with our study at the early stage of COVID-19 pandemic.
    keywords: anxiety; covid-19; depression; et al; health; nurses; risk; sars
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        item: #2930 of 7819
          id: cord-288502-qqg41daz
      author: Martini, Katharina
       title: Patterns of organizing pneumonia and microinfarcts as surrogate for endothelial disruption and microangiopathic thromboembolic events in patients with coronavirus disease 2019
        date: 2020-10-05
       words: 3619
      flesch: 42
     summary: One hypothesis is, that the high mortality observed among COVID-19 patients may be partly due to undiagnosed pulmonary embolism (PE) and pulmonary in situ thrombosis, outlining the possible role of CT pulmonary angiography (CT-PA) in patients with rapid clinical worsening On CT-PA, 13.2% of COVID-19 patients presented with PE whereas in the control-groups prevalence of PE was 9.1% and 8.9%, respectively (p = 0.452).
    keywords: artery; changes; cohort; covid-19; patients; pneumonia; ratio
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        item: #2931 of 7819
          id: cord-288508-749im18d
      author: Sourdin, Tania
       title: Court Innovations and Access to Justice in Times of Crisis
        date: 2020-08-30
       words: 5094
      flesch: 44
     summary: Essentially, the question is whether the use of artificial intelligence technology and algorithms in court systems could produce 'just' outcomes. [3] .Outside courts, where much justice work takes place, online dispute resolution (ODR) arrangements, became an increasingly important focus as delays increased in many court systems.
    keywords: access; courts; covid-19; health; justice; law; pandemic; people; rights; system
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        item: #2932 of 7819
          id: cord-288526-5zag3krb
      author: Sathish, Thirunavukkarasu
       title: Normal weight obesity and COVID-19 severity: A poorly recognized link
        date: 2020-10-21
       words: 721
      flesch: 48
     summary: Thus, people with normal weight on the BMI scale can have elevated body fat percent, particularly in the visceral area, an entity called normal weight obesity (NWO) Highlights from a unicenter cross-sectional pilot study in Germany Prevalence of normal weight obesity and its associated cardio-metabolic risk factors -Results from the baseline data of the Kerala Diabetes Prevention Program (KDPP)
    keywords: body; covid-19; obesity
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        item: #2933 of 7819
          id: cord-288552-7lp07v5i
      author: Vahedi, Ensieh
       title: The clinical value of two combination regimens in the Management of Patients Suffering from Covid-19 pneumonia: a single centered, retrospective, observational study
        date: 2020-06-19
       words: 4922
      flesch: 34
     summary: While corticosteroids were not routinely recommended for treatment of COVID-19 patients, a retrospective cohort study of COVID-19 in Wuhan, China reported the benefits of methylprednisolone by decreasing the risk of death due to COVID-19 in patients who developed ARDS On the use of corticosteroids for 2019-nCoV pneumonia Impact of corticosteroid therapy on outcomes of persons with SARS-CoV-2, SARS-CoV, or MERS-CoV infection: a systematic review and meta-analysis The effect of corticosteroid treatment on patients with coronavirus infection: a systematic review and meta-analysis Mesenchymal stem cell therapy for COVID-19: present or future A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 Lopinavir-ritonavir in severe COVID-19 Covid-19-the search for effective therapy Structure-based discovery of the novel antiviral properties of naproxen against the nucleoprotein of influenza a virus Non-steroidal anti-inflammatory drugs, pharmacology, and COVID-19 infection Inpatient use of Mobile continuous telemetry for COVID-19 patients treated with Hydroxychloroquine and azithromycin Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study A major outbreak of severe acute respiratory syndrome in Hong Kong Erythrocyte sedimentation rate and Creactive protein: how best to use them in clinical practice Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment Ni A-p. expression of lymphocytes and lymphocyte subsets in patients with severe acute respiratory syndrome Significant changes of peripheral T lymphocyte subsets in patients with severe acute respiratory syndrome Adaptive immune cells temper initial innate responses Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Acknowledgements
    keywords: combination; covid-19; disease; group; patients; regimen; study; treatment; use
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        item: #2934 of 7819
          id: cord-288559-7m6sh5xx
      author: Bhattarai, S.
       title: Assessment of service availability and Infection prevention measures in hospitals of Nepal during the transition phase of COVID-19 case surge
        date: 2020-05-19
       words: 5139
      flesch: 48
     summary: Out of 110 hospitals, 81% (22/27) of small, 39% (11/28) of medium, and 33% (18/55) of large hospitals had not allocated isolation beds for COVID-19 suspects. All small, majority of medium (89%; 25/28), and 50% of large hospitals did not have a functional intensive care unit (ICU) at the time of study.
    keywords: covid-19; facilities; health; hospitals; license; medium; medrxiv; preprint; public
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        item: #2935 of 7819
          id: cord-288566-7dtmjzj9
      author: Chai, Ningli
       title: The influence of the COVID-19 epidemic on the gastrointestinal endoscopy practice in China: a national survey
        date: 2020-11-11
       words: 2526
      flesch: 42
     summary: Number of various GI endoscopic procedures and participants getting endoscopic training from January 1 to April 10, 2020 (the COVID-19 period) and the same period of 2019 were collected and analyzed. (iii) Several recommendations and guidance worldwide called to limit endoscopic procedures to urgent endoscopic interventions and deferral of elective non-urgent endoscopic procedures.
    keywords: covid-19; endoscopy; number; pandemic; procedures
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        item: #2936 of 7819
          id: cord-288568-fjdjuksm
      author: Huang, Yuanyuan
       title: Prevalence and Correlation of Anxiety, Insomnia and Somatic Symptoms in a Chinese Population During the COVID-19 Epidemic
        date: 2020-08-28
       words: 4704
      flesch: 36
     summary: The findings showed that GAD-7 scores (OR = 1.158, 95% CI: 1.085-1.236, Wald x 2 = 19.446, p < 0.001), ISI scores (OR = 1.087, 95% CI: 1.036-1.140, Wald x 2 = 11.697, p = 0.001), and age (OR = 1.743, 95% CI: 1.049-2.894, Wald x 2 = 4.606, p = 0.032) were associated with somatization symptoms in anxiety participants, while no difference in history of physical disease was found (p > 0.05). In contrast, previous studies showed that physical symptoms may occur independent of anxiety symptoms (18, 19) , but the mechanism underlying this finding is not yet clear.
    keywords: anxiety; covid-19; epidemic; insomnia; population; somatization; study; symptoms
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        item: #2937 of 7819
          id: cord-288575-srpc68t8
      author: Yamakage, Michiaki
       title: Anesthesia in the times of COVID-19
        date: 2020-05-25
       words: 1317
      flesch: 27
     summary: Anesthesia Pediatric laryngoscopy and bronchoscopy during the COVID-19 pandemic: a four-center collaborative protocol to improve safety with perioperative management strategies and creation of a surgical tent with disposable drapes A process for daily checks when using anaesthetic machines to ventilate the lungs of COVID-19 patients: the 'domino switch' technique Management of CO 2 absorbent while using the anesthetic machine as a mechanical ventilator as a mechanical ventilator on patients with COVID Is regional anesthesia safe enough in suspected of confirmed COVID-19 patients? Much of the initial literature on the management of COVID-19 patients comes from Wuhan, China, with articles subsequently published worldwide [5] [6] [7] [8] .
    keywords: anesthesia; coronavirus; covid-19; patients
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        item: #2938 of 7819
          id: cord-288580-onzzpkye
      author: HALAÇLI, Burçin
       title: Critically ill COVID-19 patient
        date: 2020-04-21
       words: 3808
      flesch: 41
     summary: For this purpose, elective in-patient admissions and surgeries should be delayed and available wards could be adapted for stepping down other ICU patients in order to evacuate ICUs. In this review, we aimed to emphasize the crucial points regarding intensive care management of COVID-19 patients, which we have written not only for intensivists but also for all healthcare professionals.
    keywords: care; coronavirus; covid-19; icu; intubation; patients; pneumonia; pressure; risk; ventilation
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        item: #2939 of 7819
          id: cord-288632-2aliqy8p
      author: Phillips, Nicole
       title: The Perfect Storm: COVID-19 Health Disparities in US Blacks
        date: 2020-09-23
       words: 4587
      flesch: 28
     summary: Population-specific risk in Black communities is clearly multifactorial; however, recent research on the prevalence and risk in the UK indicates that comorbidity and social determinants of health only tell part of the story when it comes to accounting for disease risk and mortality in vulnerable populations While this theoretical threshold model of disease risk is a vast oversimplification, rapid advances in computational biology, facilitated by artificial intelligence, may enable researchers to capture nuanced interactions not shown in Fig. 2 in order to greatly enhance predictive power.
    keywords: ace2; cov-2; covid-19; disease; health; il-6; mortality; polymorphisms; risk; sars; stress
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        item: #2940 of 7819
          id: cord-288634-7g2kg2tz
      author: Bres Bullrich, Maria
       title: COVID-19: Stroke Admissions, Emergency Department Visits, and Prevention Clinic Referrals
        date: 2020-05-26
       words: 1781
      flesch: 47
     summary: 1,2 However, to date, no study has formally evaluated the impact of the coronavirus disease 19 (COVID-19) pandemic on the number of stroke patients being assessed in the ED, stroke admissions, or referrals to stroke prevention clinics in Canada. To compare code strokes, stroke unit admissions, and clinic referrals in 2020 against 2019, we plotted weekly numbers of consults in both years.
    keywords: clinic; number; referrals; stroke
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        item: #2941 of 7819
          id: cord-288647-qul4sz7w
      author: Edigin, Ehizogie
       title: Impact of COVID-19 pandemic on medical postgraduate training in the United States
        date: 2020-06-04
       words: 1100
      flesch: 44
     summary: Trainees are spending a considerable amount of time in these COVID services which expose trainees to only patients primarily managed for COVID-19. Medical trainee education is consolidated by a high volume of patient encounters.
    keywords: covid-19; medical; trainees
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        item: #2942 of 7819
          id: cord-288675-d4p3sj7u
      author: Sauer, François
       title: Tamponnade & COVID-19
        date: 2020-11-01
       words: 1820
      flesch: 57
     summary: Son examen clinique retrouve une tension artérielle à 106/60 mmHg, une fréquence cardiaque à 108 battements par minute, une température corporelle à 36° et une saturation à 24 mmhg sur le flux d'IT (insuffisance tricuspide) (Fig. 5) .
    keywords: covid-19; des; les; par; une
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        item: #2943 of 7819
          id: cord-288679-57ftpsmx
      author: Ramirez, David A.
       title: Resident Perspectives on COVID-19: Three Takeaways
        date: 2020-09-22
       words: 1417
      flesch: 39
     summary: When our leadership announced ophthalmology residents would not be called to manage inpatients, our fear lessened, but feelings of guilt surfaced. Thematic analyses of medical interns have shown that depressed residents cite higher rates of lacking faculty interest and malignant program culture than their non-depressed counterparts.
    keywords: ophthalmology; program; residents; simulation; training
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        item: #2944 of 7819
          id: cord-288720-bd86zswo
      author: Lin, Sheng
       title: Epidemiological and clinical characteristics of 161 discharged cases with coronavirus disease 2019 in Shanghai, China
        date: 2020-10-20
       words: 3318
      flesch: 48
     summary: As far as we know, this research includes the largest discharged COVID-19 case series and report an initial evaluation of the epidemiological characteristics, clinical characteristics, laboratory results, and disease course of COVID-19 cases. We aimed to further describe the epidemiological and clinical characteristics of discharged COVID-19 cases and evaluate the public health interventions.
    keywords: cases; covid-19; days; median; onset; shanghai; time
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        item: #2945 of 7819
          id: cord-288732-k763ejqb
      author: ElMajjaoui, Sanaa
       title: COVID-19, Brachytherapy, and Gynecologic Cancers: a Moroccan Experience
        date: 2020-07-15
       words: 1740
      flesch: 34
     summary: COVID-19 and gynecological cancers: a Moroccan point-of-view Radiation therapy for gynecologic malignancies during the COVID-19 pandemic: international expert consensus recommendations Epidemiology and outcome of cervical cancer in national institute of Morocco FIGO IIIB squamous cell carci-noma of the cervix: an analysis of prognostic factors emphasizing the balance between external beam and intracavitary radiation therapy Brachytherapy versus radical hysterectomy after external beam chemoradiation with gemcitabine plus cisplatin: a randomized, phase III study in IB2-IIB cervical cancer patients Clinical impact of MRI assisted dose volume adaptation and dose esca-lation in brachytherapy of locally advanced cervix cancer MRI-guided adaptive radiotherapy in locally advanced cervical cancer from a Nordic perspective Image guided brachytherapy in locally advanced cervical cancer: improved pelvic control and survival in RetroEMBRACE, a multicenter cohort study Figo IIIB squamous cell carcinoma of the cervix: an analysis of prog-nostic factors emphasizing the balance between external beam and intracavitary radiation therapy Differences in outcome for cervical cancer patients treated with or without brachyther-apy Imageguided radiotherapy for cervix cancer: high-tech external beam ther-apy versus high-tech brachytherapy Image guided brachytherapy in locally advanced cervical cancer: improved pelvic control and survival in RetroEMBRACE, a multicenter cohort study Recommendations from Gynaecological (GYN) GEC-ESTRO Working Group (I): concepts and terms in 3D image based 3D treatment planning in cervix cancer brachytherapy with emphasis on MRI assessment of GTV and CTV Recommendations from gynaecological (GYN) GEC ESTRO working grooooup (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology Computed tomography versus magnetic resonance imaging-based contouring in cervical cancer brachytherapy: results of a prospective trial and preliminary guidelines for standardized contours COVID-19 impact on timing of brachytherapy treatment and strategies for risk mitigation RTOG 0417. Brachytherapy treatment should be started on time without any delay.
    keywords: brachytherapy; cancer; covid-19; patients; treatment
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        item: #2946 of 7819
          id: cord-288738-anouedix
      author: Mathew, Rishi Philip
       title: The Role of Non-Contrast Chest CT in Suspected or Confirmed Coronavirus Disease 2019 (COVID-19) Pediatric Patients
        date: 2020-05-18
       words: 496
      flesch: 36
     summary: Based on this clinical information, we felt the need to bring to the attention of the pediatric physicians and surgeons, especially those battling against confirmed COVID-19 cases, the potential of chest CT and the valuable information it can provide. COVID-19 disease in the pediatric population is mostly mild [4] , with the most common CT findings being unilateral or bilateral subpleural ground-glass opacities, and consolidations with surrounding halo sign [5] .
    keywords: covid-19
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        item: #2947 of 7819
          id: cord-288770-hquc2v2c
      author: Gupta, Rajan
       title: A Comprehensive Analysis of COVID-19 Outbreak situation in India
        date: 2020-04-11
       words: 5880
      flesch: 58
     summary: Based on the exponential modelling based growth of the number of COVID-19 cases in India, polynomial regression line was plotted with different degree values. Coronavirus disease (COVID-19) Pandemic, WHO Novel Coronavirus (COVID-19) Cases, provided by JHU CSSE India's swiftness in dealing with Covid-19 will decide the world's future, says WHO, Quartz India India is now the world's 5th largest economy, World Economic Forum Trend Analysis and Forecasting of COVID-19 outbreak in India SEIR and Regression Model based COVID-19 outbreak predictions in India.
    keywords: cases; covid-19; growth; india; lockdown; number; patients; preprint; study; time
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        item: #2948 of 7819
          id: cord-288787-9g2vpdj3
      author: Bitonti, Giovanna
       title: Being an Obstetrics and Gynaecology Resident during the COVID-19: Impact of the Pandemic on the residency training program
        date: 2020-08-01
       words: 2684
      flesch: 47
     summary: A one-third reduction was reported in 31,4% of the cases, whereas a total suspension of the training in 9,9% of the cases. A one-third reduction was reported in 31,4% of the cases, whereas a total suspension of the training in 9,9% of the cases.
    keywords: cases; covid-19; obstetrics; residents; training
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        item: #2949 of 7819
          id: cord-288810-ab7k70c4
      author: Zheng, Yingyan
       title: Development and Validation of a Prognostic Nomogram Based on Clinical and CT Features for Adverse Outcome Prediction in Patients with COVID-19
        date: 2020-06-24
       words: 3376
      flesch: 39
     summary: Notably, patients who experienced adverse clinical outcomes tended to demonstrate crazy-paving sign to a more abnormal extent on admission. Clinical characteristics of coronavirus disease 2019 in China Fleischner Society: glossary of terms for thoracic imaging Severe acute respiratory syndrome: temporal lung changes at thin-section CT in 30 patients Epidemiology, genetic recombination, and pathogenesis of coronaviruses Origin and evolution of pathogenic coronaviruses Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Prognostic Nomogram for Adverse Outcome Prediction in Patients with COVID-19 Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Sexual dimorphism in innate immunity Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Radiology perspective of coronavirus disease 2019 (COVID-19): lessons from severe acute respiratory syndrome and Middle East respiratory syndrome Prognostic significance of crazy paving ground grass opacities in non-HIV pneumocystis Jirovecii pneumonia: an observational cohort study
    keywords: cohort; coronavirus; covid-19; features; patients; prognostic; validation
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        item: #2950 of 7819
          id: cord-288818-6uvb4qsk
      author: Tanveer, Faouzia
       title: Ethics, pandemic and environment; looking at the future of low middle income countries
        date: 2020-10-15
       words: 7005
      flesch: 41
     summary: World Health Organization US emergency legal responses to novel coronavirus: balancing public health and civil liberties Responding to COVID-19: how to navigate a public health emergency legally and ethically Combating COVID-19: health equity matters Ethical standards for research during public health emergencies: distilling existing guidance to support COVID-19 R&D: During a pandemic, standard crises care protocols should be developed by public health institutions to establish a systematic and evidence based procedure which ensures fair distribution of health care resources.
    keywords: care; cases; countries; cov-2; covid-19; data; health; information; pandemic; public; research; resources; response; sars; spread
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        item: #2951 of 7819
          id: cord-288836-bygcyxpz
      author: Manes, Gianpiero
       title: Planning Phase Two for Endoscopic Units in Northern Italy after the COVID-19 lockdown: an exit strategy with a lot of critical issues and a few opportunities
        date: 2020-06-19
       words: 2158
      flesch: 45
     summary: Indeed, most participants agreed that re-opening EDs should be accomplished very slowly, with a limited increase in the number of procedures over the upcoming months and that it was unrealistic to return to pre-crisis workload in the next three months. We conducted a survey among the Directors of EDs in high-risk areas of Northern Italy with the aim of investigating the barriers and strategies to safely resume elective endoscopy activity in Phase Two of the lockdown.
    keywords: activity; covid-19; eds; endoscopy; procedures
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        item: #2952 of 7819
          id: cord-288843-zxv5vsro
      author: Ianiro, Gianluca
       title: Screening of faecal microbiota transplant donors during the COVID-19 outbreak: suggestions for urgent updates from an international expert panel
        date: 2020-03-17
       words: 1643
      flesch: 35
     summary: Patients encountered early in our experience of using faecal bacteriotherapy to treat recurrent Clostridioides difficile infection included a woman admitted to hospital six times with severe complicated infections and a toddler who had been on antibiotics for more than half of his life, who had relentless severe diarrhoea and weight loss due to recurrent C difficile infection. Previously considered to be a last resort, the practice of FMT has greatly increased since the first randomised controlled trial (RCT) was published in 2013, 1 with strong consensus among doctors doing the procedure that FMT is the most effective option for recurrent C difficile infection.
    keywords: covid-19; difficile; donors; fmt; infection
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        item: #2953 of 7819
          id: cord-288863-buis3y21
      author: Henry, Robert
       title: Innovations in Agriculture and Food Supply in Response to the COVID-19 Pandemic
        date: 2020-07-22
       words: 1838
      flesch: 45
     summary: People and countries could aim to be more self-sufficient in food production to reduce reliance on food supply from other places or countries. The pandemic has focused attention on the critical importance of continued food production and distribution and some of the approaches developed to ensure food supply might be retained in the longer term.
    keywords: covid-19; food; pandemic; plant; production
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        item: #2954 of 7819
          id: cord-288865-5hu8i546
      author: Xu, Gang
       title: New view on older adults with COVID-19: comments on “SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes”
        date: 2020-07-24
       words: 1342
      flesch: 45
     summary: Atypical COVID-19 patients are with risks of transmission, and the neglect of atypical symptoms may delay the diagnosis and treatment of patients, which may be disastrous in older patients; therefore, special considerations should be paid to older atypical patients. This was echoed by the lower serum albumin in older COVID-19 patients than in younger patients (Chen et al. 2020b; Liu et al. 2020) .
    keywords: patients
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        item: #2955 of 7819
          id: cord-288867-iicfe7il
      author: Bauch, Chris T
       title: COVID-19: when should quarantine be enforced?
        date: 2020-05-20
       words: 926
      flesch: 44
     summary: And even if contact tracing fails to contain an outbreak, the combined effect of physical distancing and contact tracing is greater than the effect of either intervention on its own. Contact tracing represents a race to trace.
    keywords: contacts; covid-19; quarantine
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        item: #2956 of 7819
          id: cord-288903-vxeq1afx
      author: Lodha, Rakesh
       title: COVID-19 Pandemic: The Way Forward
        date: 2020-05-26
       words: 2302
      flesch: 46
     summary: It is expected that even if COVID-19 infection rate decreases over next few weeks/months, risk of infection will persist and second surge later this year cannot be ruled out. Opportunity to Improve Healthcare in India COVID-19 pandemic has given us an opportunity to identify our limitations in healthcare and improve it by innovation.
    keywords: covid-19; healthcare; india; infection; need; patients
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        item: #2957 of 7819
          id: cord-288919-3ay39zf5
      author: Müller, Helmut
       title: Recovery from COVID‐19 following hepatitis C, human immunodeficiency virus infection, and liver transplantation
        date: 2020-06-18
       words: 231
      flesch: 23
     summary: To the Editor: COVID-19 in longterm liver transplant patients: preliminary experience from an Italian transplant centre in Lombardy Metroticket 2.0 model for analysis of competing risks of death after liver transplantation for hepatocellular carcinoma Clinical best practice advice for hepatology and liver transplant providers during the COVID-19 pandemic: AASLD expert panel consensus statement Cyclosporine and tacrolimus have inhibitory effects on toll-like receptor signaling after liver transplantation Fatal outcome in a liver transplant recipient with COVID-19 The authors of this manuscript have no conflicts of interest to disclose as described by the American Journal of Transplantation. key: cord-288919-3ay39zf5 authors: Müller, Helmut; Kniepeiss, Daniela; Stauber, Rudolf; Schrem, Harald; Rauter, Markus; Krause, Robert; Schemmer, Peter title: Recovery from COVID‐19 following hepatitis C, human immunodeficiency virus infection, and liver transplantation date: 2020-06-18 journal: Am J Transplant DOI: 10.1111/ajt.16107 sha: doc_id: 288919 cord_uid: 3ay39zf5 Immunosuppression and frequent comorbidities in transplant recipients potentially increase the risk of fatal outcomes of pandemic coronavirus disease 2019 (COVID-19)
    keywords: liver; transplant
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        item: #2958 of 7819
          id: cord-288922-1lry9wkn
      author: Aamir, Alifiya
       title: Effect of COVID-19 on Mental Health Rehabilitation Centers
        date: 2020-10-21
       words: 1685
      flesch: 33
     summary: Since COVID-19 pandemic has remarkably raised mental health concerns, one of the high risks and possibly neglected groups includes individuals undergoing mental health rehabilitation, the impact on which can be significant as compared to the rest of the population. Since COVID-19 pandemic has remarkably raised mental health concerns, one of the high risks and possibly neglected groups includes individuals undergoing mental health rehabilitation, the impact on which can be significant as compared to the rest of the population.
    keywords: covid-19; crisis; health; rehabilitation
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        item: #2959 of 7819
          id: cord-288931-d4fyitnk
      author: Parisi, Valentina
       title: Precision medicine in COVID-19: IL-1β a potential target
        date: 2020-04-18
       words: 322
      flesch: 22
     summary: Of note, activation of NLRP3 inflammasome in macrophages attenuates uncoupling protein 1 (UCP1) induction and mitochondrial respiration in cultures of primary adipocytes and the NLRP3 inflammasome activation appears to link obesity and dysfunctional thermogenesis (5). Emerging infectious diseases Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host Mechanism of NLRP3 inflammasome activation Imbalance Between Interleukin-1β and Interleukin-1 Receptor Antagonist in Epicardial Adipose Tissue Is Associated With Non ST-Segment Elevation Acute Coronary Syndrome Inhibitory Effects of Toll-Like Receptor 4, NLRP3 Inflammasome, and Interleukin-1β on White Adipocyte Browning
    keywords: nlrp3
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        item: #2960 of 7819
          id: cord-288983-a6s9di4g
      author: Su, Sheng-Fang
       title: How Taiwan, a non-WHO member, takes actions in response to COVID-19
        date: 2020-06-17
       words: 1822
      flesch: 45
     summary: Taiwan CDC sent an email to WHO International Health Regulations (IHR): News resources today indicate that at least seven atypical pneumonia cases were reported in Wuhan, China. Taiwan designated 134 response and isolation hospitals, as well as 52 regional hospitals or medical centers for treatment of confirmed cases, to establish the Communicable Disease Control Medical Network (CDCMN)
    keywords: cases; covid-19; health; isolation; quarantine; taiwan
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        item: #2961 of 7819
          id: cord-288997-cb7ndzqt
      author: Dey, Thonmoy Josh
       title: Ethnicity and COVID-19 - A commentary on “World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19)” (Int J Surg 2020;76:71-6)
        date: 2020-09-11
       words: 1522
      flesch: 49
     summary: The first indicators of a vulnerable population came in the form of reports of BAME health workers dying from COVID-19, prompting the government to launch a review [4] . However, can these unfavourable COVID-19 outcomes be entirely attributed to increased comorbidity representation in BAME groups or are there other factors to consider?
    keywords: bame; covid-19; groups; health
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        item: #2962 of 7819
          id: cord-288998-0by0bkgs
      author: Colarusso, Chiara
       title: A lesson from a saboteur: high molecular weight kininogen (HMWK) impact in COVID‐19
        date: 2020-06-04
       words: 3862
      flesch: 31
     summary: In the first published cohort of 41 laboratory-confirmed cases infected with SARS-CoV-2 (Huang et al. 2020) , it was reported that infected patients had a median age of 49.0 years and 73% of them were men. The morbidity is mainly due to respiratory failure typical of acute respiratory distress syndrome (ARDS), but the mortality underlies multiple organ failure due to coagulation alteration with ensuing thrombosis and embolism, consequences of septic shock and/or cardiovascular alterations (Huang et al. 2020 ).
    keywords: ace2; angiotensin; coronavirus; cov-2; covid-19; patients; receptor; sars
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        item: #2963 of 7819
          id: cord-289006-7dv1zsp9
      author: Tan, Kimberly-Anne
       title: Addressing Coronavirus Disease 2019 in Spine Surgery: A Rapid National Consensus Using the Delphi Method via Teleconference
        date: 2020-05-14
       words: 4531
      flesch: 36
     summary: The efficacy of these swift draconian measures, guided in-part by bitter lessons learned during the 2003 SARS pandemic [3] , was reflected by the low rate of new COVID-19 cases, garnering Singapore international praise for what appeared an early flattening of the curve [4, 5] . However, given the inherently wide spectrum and time-sensitive nature in which spine pathologies tend to present, triaging spine cases while balancing the duties of a spine surgeon and managing COVID-19 cases has proven challenging (as discussed in a subsequent section).
    keywords: cases; covid-19; pandemic; patients; services; singapore; spinal; spine; surgeons; surgery; testing
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        item: #2964 of 7819
          id: cord-289008-c4cu3vrp
      author: Wallis, Christopher J.D.
       title: Risks from Deferring Treatment for Genitourinary Cancers: A Collaborative Review to Aid Triage and Management During the COVID-19 Pandemic
        date: 2020-05-03
       words: 9378
      flesch: 41
     summary: The timing of radical cystectomy for bacillus Calmette-Guerin failure: comparison of outcomes and risk factors for prognosis Transurethral resection of bladder tumour: the neglected procedure in the technology race in bladder cancer A systematic review and meta-analysis of delay in radical cystectomy and the effect on survival in bladder cancer patients Longer wait times increase overall mortality in patients with bladder cancer Delaying radical cystectomy after neoadjuvant chemotherapy for muscle-invasive bladder cancer is associated with adverse survival outcomes Delays in radical cystectomy for muscle-invasive bladder cancer A delay 8 weeks to neoadjuvant chemotherapy before radical cystectomy increases the risk of upstaging Assessing the impact of time to cystectomy for variant histology of urothelial bladder cancer Updated 2016 EAU guidelines on muscle-invasive and metastatic bladder cancer Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China Effectiveness of adjuvant chemotherapy for locally advanced bladder cancer Radiotherapy with or without chemotherapy in muscleinvasive bladder cancer Efficacy and safety of dose-dense chemotherapy in urothelial carcinoma Clinical outcome after progressing to frontline and second-line Anti-PD-1/PD-L1 in advanced urothelial cancer Adverse event profile for immunotherapy agents compared with chemotherapy in solid organ tumors: a systematic review and meta-analysis of randomized clinical trials Advice regarding systemic therapy in patients with urological cancers during the COVID-19 pandemic Cancer statistics Cancer statistics, 2020 Co-morbidities in a retrospective cohort of prostate cancer patients Feasibility study: watchful waiting for localized low to intermediate grade prostate carcinoma with selective delayed intervention based on prostate specific antigen, histological and/or clinical progression 10-Year outcomes after monitoring, surgery, or radiotherapy for localized prostate cancer Ten-year mortality, disease progression, and treatmentrelated side effects in men with localised prostate cancer from the ProtecT randomised controlled trial according to treatment received Active surveillance for intermediate risk prostate cancer: survival outcomes in the Sunnybrook experience Impact of the length of time between diagnosis and surgical removal of urologic neoplasms on survival Timing of curative treatment for prostate cancer: a systematic review Evaluating the impact of length of time from diagnosis to surgery in patients with unfavourable intermediate-risk to very-high-risk clinically localised prostate cancer While acknowledging the significant psychologic burden associated with a cancer diagnosis, likely magnified by delays in treatment, physicians who treat cancer patients must be good stewards of limited health care resources, particularly in the time of a pandemic.
    keywords: cancer; carcinoma; covid-19; delays; disease; metastatic; outcomes; patients; risk; studies; survival; therapy; treatment
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        item: #2965 of 7819
          id: cord-289029-6vcjioon
      author: Suri, Abdul Wahab
       title: The Rejuvenation of the Withering Nation State and Bio-power: The New Dynamics of Human Interaction
        date: 2020-08-25
       words: 2786
      flesch: 48
     summary: The brute expression of state power is working because state authorities are seeking legitimacy from healthcare professionals for the use of coercive measures. The financial markets are globalized in such a manner that nation states are constantly losing their capacity to perform redistributive functions.
    keywords: covid-19; healthcare; nation; power; state
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        item: #2966 of 7819
          id: cord-289041-lhc53uk4
      author: Nadeem, Muhammad Faisal
       title: Is the paradigm of community pharmacy practice expected to shift due to COVID-19?
        date: 2020-05-27
       words: 1463
      flesch: 26
     summary: This discussion aims to give overview of the emerging services and flexibilities in pharmaceutical regulations that could shift the paradigm of community pharmacy practice and help community pharmacists move from the bleeding edge to the cutting edge ( Figure 1 ). Moreover, this letter is expected to pique the attention of pharmaceutical regulatory bodies in developing nations towards the potential of community pharmacy services to knock down challenges concerning COVID-19 havoc.
    keywords: community; covid-19; pharmacists; pharmacy; services
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        item: #2967 of 7819
          id: cord-289046-frhpt8n9
      author: Fix, Oren K.
       title: Telemedicine and Telehepatology During the COVID‐19 Pandemic
        date: 2020-05-21
       words: 1475
      flesch: 43
     summary: As a result, there has been a sudden and substantial increase in telemedicine visits for urgent and nonurgent ambulatory care both related and unrelated to COVID-19, and patient satisfaction for telemedicine care has been consistently high. The Centers for Medicare and Medicaid Services (CMS) places substantial barriers to the use of telemedicine by restricting it to patients who reside in rural areas and who must travel to a local medical facility (e.g., doctor's office, hospital, dialysis facility, or skilled nursing facility) to receive telemedicine services from a doctor in a remote location.
    keywords: care; covid-19; patients; telemedicine
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        item: #2968 of 7819
          id: cord-289064-435bp4rt
      author: Muniangi-Muhitu, Hermine
       title: Covid-19 and Diabetes: A Complex Bidirectional Relationship
        date: 2020-10-08
       words: 5755
      flesch: 32
     summary: We consider roles for the immune system, the observed phenomenon of microangiopathy in severe Covid-19 infection and the potential for direct viral toxicity on metabolically-relevant tissues including pancreatic beta cells and targets of insulin action. The most common comorbidities with Covid-19 infection are metabolic diseases including diabetes, hypertension, obesity and cardiovascular disease (9, 10, 13) .
    keywords: ace2; cells; covid-19; diabetes; disease; immune; infection; insulin; patients; receptor; risk; sars; type
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        item: #2969 of 7819
          id: cord-289067-ptqzvsdw
      author: Bansal, Priya
       title: Clinician Wellness During the COVID-19 Pandemic: Extraordinary Times and Unusual Challenges for the Allergist/Immunologist
        date: 2020-04-04
       words: 8143
      flesch: 43
     summary: The rapid adoption of telehealth is a critical component of COVID-19 care. health care resources were overwhelmed within a few weeks.
    keywords: allergy; burnout; care; clinicians; covid-19; health; help; immunology; information; media; medical; pandemic; patients; physicians; practice; resources; time; wellness
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        item: #2970 of 7819
          id: cord-289078-wauwq841
      author: Roxby, Alison C
       title: Lessons from Sweden: where can older adults shelter from COVID-19?
        date: 2020-10-28
       words: 1079
      flesch: 44
     summary: Older adults who lived with an adult of working age (<66 years) also had higher risk of COVID-19 mortality compared with those who lived with other older adults. key: cord-289078-wauwq841 authors: Roxby, Alison C; Gure, Tanya R title: Lessons from Sweden: where can older adults shelter from COVID-19? date: 2020-10-28 journal: nan DOI: 10.1016/s2666-7568(20)30035-0 sha: doc_id: 289078 cord_uid: wauwq841 nan Hospitalisation and mortality during the COVID-19 pandemic has been concentrated in older adults, 1,2 with devastating outbreaks occurring in congregate settings.
    keywords: adults; covid-19; risk
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        item: #2971 of 7819
          id: cord-289088-7uoia564
      author: Ding, Qiang
       title: The clinical characteristics of pneumonia patients coinfected with 2019 novel coronavirus and influenza virus in Wuhan, China
        date: 2020-03-30
       words: 1520
      flesch: 43
     summary: We found that only one of five patients had T A B L E 1 Clinical characteristics of patients infected with COVID-19 and influenza virus when admitted to hospital Signs and symptoms patients) had diarrhea during the treatment period. key: cord-289088-7uoia564 authors: Ding, Qiang; Lu, Panpan; Fan, Yuhui; Xia, Yujia; Liu, Mei title: The clinical characteristics of pneumonia patients coinfected with 2019 novel coronavirus and influenza virus in Wuhan, China date: 2020-03-30 journal: J Med Virol DOI: 10.1002/jmv.25781 sha: doc_id: 289088 cord_uid: 7uoia564 The outbreak of 2019 novel coronavirus (COVID‐19) infection emerged in Wuhan, China, in December 2019.
    keywords: clinical; influenza; patients; virus
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        item: #2972 of 7819
          id: cord-289091-djv4syy4
      author: Ullah, Waqas
       title: Safety and Efficacy of Hydroxychloroquine in COVID-19: A Systematic Review and Meta-Analysis
        date: 2020-07-04
       words: 3388
      flesch: 49
     summary: Our mortality analysis of 3,004 (HCQ group: 1,907; control: 1,097) showed a significantly higher rate of all-cause mortality in patients in HCQ group compared to those on SCT. In light of these trends and with previous studies demonstrating major side effects of HCQ (cardiomyopathy, QT prolongation, and retinopathy), a considered risk to benefit determination should be made prior to HCQ use.
    keywords: analysis; control; covid-19; efficacy; hcq; patients; studies; study
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        item: #2973 of 7819
          id: cord-289101-ko1knslk
      author: Fu, Weihui
       title: An open-label, randomized trial of the combination of IFN-κ plus TFF2 with standard care in the treatment of patients with moderate COVID-19
        date: 2020-09-20
       words: 6202
      flesch: 42
     summary: This was an open-label, randomized clinical trial conducted from March 23, 2020, for virologically confirmed COVID-19 patients Evidence before this study We searched Pubmed and China National Knowledge Infrastructure database for articles that use TFF2, IFN-k, or the combination of both, to treat COVID-19 patients on March 23, 2020 using the search terms (novel coronavirus OR SARS-CoV-2 00 OR COVID-19 00 ) AND (TFF2 OR IFN-k) with no language or time restrictions. Unfortunately, most studies have shown limited therapeutic effects in COVID-19 patients, and some effective therapeutics in published papers have been questioned for various reasons [33] .
    keywords: aerosol; control; covid-19; days; group; ifn; inhalation; patients; study; tff2; treatment
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        item: #2974 of 7819
          id: cord-289103-6i7wf41w
      author: McElyea, Christine
       title: Lung ultrasound artifacts in COVID-19 patients
        date: 2020-08-25
       words: 1761
      flesch: 44
     summary: Reply Relevance of lung ultrasound in the diagnosis of acute respiratory failure: the BLUE protocol Covid-19 does not lead to a Typical acute respiratory distress syndrome Usefulness of ultrasound lung comets as a nonradiologic sign of extravascular lung water The role of ultrasound lung artifacts in the diagnosis of respiratory diseases Effectiveness of rapid lung ultrasound training program for gynecologists and obstetricians managing pregnant women with suspected COVID-19 Social consequences of COVID-19 in a low resource setting in Sierra Leone, West Africa Lung ultrasound is an essential tool in identifying lung disease and most practitioners will be able to identify pathology not visible on chest X-Ray
    keywords: chest; covid-19; lung; patients; ultrasound
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        item: #2975 of 7819
          id: cord-289111-6725jg29
      author: Field, Nicholas C.
       title: Decrease in Neurosurgical Program Volume During COVID-19: Residency Programs Must Adapt
        date: 2020-06-25
       words: 969
      flesch: 51
     summary: Our resident service was split into an on-call and backup team due to the decrease in case volume, and also to limit exposure to COVID-19, and provide coverage in the Neuro ICU. The long-term implications of the outbreak are unclear, but neurosurgical residency programs must consider the long -term effects on resident education and develop an internal roadmap moving forward.
    keywords: covid-19; decrease; state
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        item: #2976 of 7819
          id: cord-289114-ifnk41oq
      author: Singh, Angaraj
       title: Effect of pre‐existing diseases on COVID‐19 infection and role of new sensors and biomaterials for its detection and treatment
        date: 2020-10-28
       words: 6903
      flesch: 48
     summary: All rights reserved Treatment of severe acute respiratory syndrome with lopinavir/ritonavir: a multicentre retrospective matched cohort study Use of convalescent plasma therapy in SARS patients in Hong Kong Clinical Trials. All rights reserved A novel human coronavirus: Middle East respiratory syndrome human coronavirus Loneliness as a public health issue: the impact of loneliness on health care utilization among older adults Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor The mechanism of resistance to favipiravir in influenza The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus Critical care utilization for the COVID-19 outbreak in Lombardy, Italy: early experience and forecast during an emergency response Isolation and characterization of viruses related to the SARS coronavirus from animals in Southern China Myocardial injury may be key in predicting COVID-19 fatalities The origin, transmission and clinical therapies on coronavirus disease-2019 (COVID-19) outbreak -an update on the Status Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2 cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Clinical features of patients infected with 2019 novel coronavirus in Wuhan Accepted Article
    keywords: article; copyright; coronavirus; cov-2; covid-19; detection; et al; infection; novel; patients; pcr; plasma; rights; sars; treatment
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        item: #2977 of 7819
          id: cord-289115-bntcn0m6
      author: Thangaraju, Pugazhenthan
       title: Role of Dupilumab in Approved Indications of COVID-19 Patient: an Efficacy-Based Nonsystematic Critical Analysis
        date: 2020-09-10
       words: 2138
      flesch: 44
     summary: There are isolated case reports and series that document a milder course of COVID-19 infection in patients who have already been on dupilumab therapy for treatment of conditions such as atopic dermatitis and chronic rhino-sinusitis with nasal polyp. The International League of Dermatological Society (ILDS) guidance in contrast asserts that current evidence does not justify the discontinuation of dupilumab therapy for AD in healthy subjects [8] .
    keywords: covid-19; dupilumab; infection; patients; therapy
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        item: #2978 of 7819
          id: cord-289144-d6fgs8qg
      author: Sieńko, Jerzy
       title: COVID-19: The Influence of ACE Genotype and ACE-I and ARBs on the Course of SARS-CoV-2 Infection in Elderly Patients
        date: 2020-07-21
       words: 5138
      flesch: 42
     summary: Given the lack of Angiotensin II, an increase in ACE2 receptors and a reduction in general inflammation. In 2007, Danser et al proposed ACE phenotyping to explain 69 Due to many variables such as age, gender and comorbidities, they were unable to determine the effect of these drugs on the development of infection, but they proved that patients using ACE-I had an increase in the number of ACE2 receptors.
    keywords: ace2; angiotensin; arbs; covid-19; disease; hypertension; infection; patients; receptor; sars; treatment
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        item: #2979 of 7819
          id: cord-289154-rwk2wajl
      author: Yeo, Danson
       title: COVID-19 and the General Surgical Department – Measures to Reduce Spread of SARS-COV-2 Among Surgeons
        date: 2020-04-13
       words: 1535
      flesch: 53
     summary: Despite having seen and surgically managed confirmed COVID-19 patients, we do not have any instances of HCW transmission so far. NCID is currently the frontline hospital for the screening and management of COVID-19 patients in Singapore.
    keywords: covid-19; department; patients; transmission
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        item: #2980 of 7819
          id: cord-289168-h27tkdal
      author: Froelich, Sébastien
       title: Towards individualized and optimalized positioning of non-ventilated COVID-19 patients: Putting the affected parts of the lung(s) on top?
        date: 2020-05-28
       words: 1145
      flesch: 33
     summary: Considered together, these hypotheses have led us to recommend that COVID-19 patients should undergo a specific assessment at admission to determine their saturation-optimalized in-bed position. In addition, an awake prone position was also mentioned by a Chinese team as one of three interventions allowing them to reduce the risk of having to escalate the management of COVID-19 patients to invasive mechanical ventilation [5] .
    keywords: patients; position; saturation
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        item: #2981 of 7819
          id: cord-289175-n95j94ck
      author: GOSTIN, LAWRENCE O.
       title: Responding to COVID‐19: How to Navigate a Public Health Emergency Legally and Ethically
        date: 2020-03-26
       words: 3597
      flesch: 47
     summary: When balanced against public health interests, a basic rule is that governments should employ the least restrictive means necessary to protect public health. And how do we ethically and legally balance public health with civil liberties?
    keywords: care; covid-19; distancing; health; isolation; needs; people; public
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        item: #2982 of 7819
          id: cord-289188-hf9sh9vs
      author: Salazar, M. R.
       title: EFFECT OF CONVALESCENT PLASMA ON MORTALITY IN PATIENTS WITH COVID-19 PNEUMONIA
        date: 2020-10-09
       words: 3055
      flesch: 42
     summary: Blood Transfus Treatment of COVID-19 with convalescent plasma: lessons from past coronavirus outbreaks The Emerging Role of Convalescent Plasma in the Treatment of COVID-19 Use of convalescent plasma therapy in SARS patients in Hong Kong Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience Experience of using convalescent plasma for severe acute respiratory syndrome among healthcare workers in a Taiwan hospital Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19: Our objective was to compare epidemiological characteristics and outcomes between patients who received convalescent plasma for COVID-19 and those who did not, admitted to hospitals in Buenos Aires Province, Argentina, throughout the pandemic.
    keywords: convalescent; license; medrxiv; patients; plasma; preprint
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        item: #2983 of 7819
          id: cord-289201-pcnba40n
      author: Janus, Scott E.
       title: Prognostic Value of Left Ventricular Global Longitudinal Strain in COVID-19
        date: 2020-07-03
       words: 589
      flesch: 38
     summary: While left ventricular global longitudinal strain (GLS) has been well validated as a prognostic cardiovascular marker (3) , the utility of left ventricular GLS in risk stratification of COVID-19 remains unknown. This is congruent with prior literature of left ventricular strain as a more powerful predictor of all cause death than visual ejection fraction even when adjusted for multiple confounders(3).
    keywords: covid-19; strain
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        item: #2984 of 7819
          id: cord-289235-slkqu1pt
      author: Carrabba, Giorgio
       title: Neurosurgery in an infant with COVID-19
        date: 2020-04-22
       words: 491
      flesch: 34
     summary: To our knowledge, no reports exist regarding the risk of general anaesthesia in infants with COVID-19. This case might reflect a general observation of relative resistance of babies and children to 4 suggesting the possibility that paucisymptomatic infants with COVID-19 can undergo major surgical procedures without additional morbidity.
    keywords: covid-19; shunt
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        item: #2985 of 7819
          id: cord-289266-4830qw10
      author: Borchert, Alex
       title: Managing Urology Consultations during COVID-19 Pandemic: Application of a Structured Care Pathway
        date: 2020-04-21
       words: 1075
      flesch: 41
     summary: COVID-19 associated consultations represented 18/53 (34.0%) of all consultations during this period, and of these, 8/18 (44.4%) were managed successfully via Telemedicine alone. Of note, while 34.0% of consultations in the 2020 study period were for COVID-19 status positive or COVID-19 status pending patients, our hospital has quickly become a majority COVID-19 facility, and we expect the majority of urology consultations moving forward during this pandemic to be classified as either Telemedicine or High-risk, and managed accordingly.
    keywords: consultations; consults; covid-19
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        item: #2986 of 7819
          id: cord-289272-bhq4t850
      author: Rosario, Denes K.A.
       title: Relationship between COVID-19 and weather: Case study in a tropical country
        date: 2020-06-19
       words: 454
      flesch: 45
     summary: Investigation of 209 effective climatology parameters on COVID-19 outbreak in Iran How will 212 country-based mitigation measures influence the course of the COVID-19 epidemic? key: cord-289272-bhq4t850 authors: Rosario, Denes K.A.; Mutz, Yhan S.; Bernardes, Patricia C.; Conte-Junior, Carlos A. title: Relationship between COVID-19 and weather: Case study in a tropical country date: 2020-06-19 journal: Int J Hyg Environ Health DOI: 10.1016/j.ijheh.2020.113587 sha: doc_id: 289272 cord_uid: bhq4t850 This study aimed to evaluate the relationship between weather factors (temperature, humidity, solar radiation, wind speed, and rainfall) and COVID-19 infection in the State of Rio de Janeiro, Brazil.
    keywords: correlation; covid-19
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        item: #2987 of 7819
          id: cord-289282-4oz6r7op
      author: Hon, Kam Lun
       title: Overview: The history and pediatric perspectives of severe acute respiratory syndromes: Novel or just like SARS
        date: 2020-06-01
       words: 3561
      flesch: 51
     summary: Summary of probable SARS cases with onset of illness from The SARS epidemic in Hong Kong Laboratory diagnosis of SARS Severe acute respiratory syndrome (SARS): Development of diagnostics and antivirals Severe acute respiratory syndrome in children Clinical presentations and outcome of severe acute respiratory syndrome in children Severe acute respiratory syndrome among children Severe acute respiratory syndrome in children: Experience in a regional hospital in Hong Kong IpPL-S. Osteonecrosis in children with severe acute respiratory syndrome Clinical features, diagnosis, treatment and short-term outcome of severe acute respiratory syndrome (SARS) in children Severe acute respiratory syndrome (SARS) in children: epidemiology, presentation and management Childhood SARS in Hong Kong Middle East respiratory syndrome World Health Organization. 19 Follow-up of SARS patients at 6 months after the illness only showed mild residual changes in exercise tolerance and pulmonary function.
    keywords: cases; children; coronavirus; covid-19; novel; patients; sars; symptoms; syndrome
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        item: #2988 of 7819
          id: cord-289304-9srk0ohb
      author: Bagnato, Sergio
       title: Critical illness myopathy after COVID-19
        date: 2020-08-05
       words: 1724
      flesch: 40
     summary: Since rehabilitation programs can be effective to reverse muscle weakness caused by CIM, health systems must plan to provide adequate access to rehabilitative facilities for patients requiring both pulmonary and motor rehabilitative treatment after COVID-19. key: cord-289304-9srk0ohb authors: Bagnato, Sergio; Boccagni, Cristina; Marino, Giorgio; Prestandrea, Caterina; D’Agostino, Tiziana; Rubino, Francesca title: Critical illness myopathy after COVID-19 date: 2020-08-05 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.07.072 sha: doc_id: 289304 cord_uid: 9srk0ohb We describe a patient who developed diffuse and symmetrical muscle weakness after a long stay in the intensive care unit (ICU) due to coronavirus disease 2019 (COVID-19).
    keywords: icu; muscle; patient; weakness
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        item: #2989 of 7819
          id: cord-289312-3vehcvhc
      author: Akintayo, Richard O
       title: COVID-19 and African rheumatology: progress in adversity
        date: 2020-09-30
       words: 1173
      flesch: 32
     summary: key: cord-289312-3vehcvhc authors: Akintayo, Richard O; Kalla, Asgar; Adebajo, Adewale title: COVID-19 and African rheumatology: progress in adversity date: 2020-09-30 journal: Lancet Rheumatol DOI: 10.1016/s2665-9913(20)30347-7 sha: doc_id: 289312 cord_uid: 3vehcvhc nan The pandemic of COVID-19, the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), hit Africa later than much of Asia, Europe, and North America. However, the cataclysm of COVID-19 has taught us major lessons and incited the potential for rapid growth in African rheumatology after the pandemic subsides.
    keywords: africa; covid-19; patients; rheumatology
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        item: #2990 of 7819
          id: cord-289315-8bfafpe0
      author: Trubiano, J. A.
       title: COVID-MATCH65 - A prospectively derived clinical decision rule for severe acute respiratory syndrome coronavirus 2
        date: 2020-07-02
       words: 1627
      flesch: 51
     summary: Bajema et al.(5) reported fever in 68% in a retrospective cohort study (n=210) from the USA with similar incidence rate of COVID-19 positive tests to our cohort (5% USA vs. 4.7% AUS). Clinical data from the data collection tool (baseline demographics, clinical symptoms, clinical observations) and COVID-19 testing results were extracted from Austin Health EMR platform (Cerner®) by the Data Analytics Research and Evaluation (DARE) Centre (Austin Health/University of Melbourne).
    keywords: covid-19; medrxiv; preprint; test
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        item: #2991 of 7819
          id: cord-289335-9agazyre
      author: DeWit, Andrew
       title: An Integrated Approach to Sustainable Development, National Resilience, and COVID-19 Responses: The Case of Japan
        date: 2020-08-13
       words: 2376
      flesch: 40
     summary: key: cord-289335-9agazyre authors: DeWit, Andrew; Shaw, Rajib; Djalante, Riyanti title: An Integrated Approach to Sustainable Development, National Resilience, and COVID-19 Responses: Moreover, as a Having analysed Japan's financial stimulus in responding to COVID-19 response from section 2 to 3, we turn to examine how integrated financial and economic stimulus can foster a rights-based, low carbon, resilient and sustainable recovery.
    keywords: climate; covid-19; japan; resilience; stimulus; sustainability
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        item: #2992 of 7819
          id: cord-289349-imkgpwn0
      author: Qiu, Li
       title: Strong immunity in the early two years of age links to frequent immunization of routine vaccines
        date: 2020-08-08
       words: 2047
      flesch: 45
     summary: The two groups with children aged under 2 years tended to have shorter periods between the first positive SARS-CoV-2 detection and 5 subsequent negative SARS-CoV-2 PCR results than the other groups of older children ( Fig. 1c ). Notably, our study found that children under 2 years old appeared to have stronger immunity against COVID-19 than older children.
    keywords: children; covid-19; immunity; patients; years
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        item: #2993 of 7819
          id: cord-289370-3n56low4
      author: Kim, Hong Nyun
       title: A Case of COVID-19 with Acute Myocardial Infarction and Cardiogenic Shock
        date: 2020-07-08
       words: 1862
      flesch: 41
     summary: Active surveillance and intensive treatment strategy are important for saving lives of COVID-19 patients with acute myocardial infarction. In Daegu, Korea, there was rapid increase in COVID-19 patients following the first outbreak on February 18, 2020.
    keywords: ami; covid-19; day; disease; patients; shock
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        item: #2994 of 7819
          id: cord-289372-bk348l32
      author: Lin, Chung‐Ying
       title: Using an integrated social cognition model to predict COVID‐19 preventive behaviours
        date: 2020-08-11
       words: 8644
      flesch: 32
     summary: Another important limitation is the aggregation of multiple COVID-19 preventive behaviours into a single behavioural score representing COVID-19 preventive behaviours with corresponding social cognition measures that made reference to those specific behaviours rather than the general category of COVID-19 preventive behaviours. Research should examine if targeting these factors lead to changes in COVID‐19 behaviours over time. constructs and COVID-19 preventive behaviours according to the proposed integrated model were estimated using structural equation modelling. Results.
    keywords: action; behaviours; constructs; covid-19; data; effects; efficacy; health; model; planning; preventive; self; study; time
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        item: #2995 of 7819
          id: cord-289377-2vqqabum
      author: Yubero, P.
       title: Evidence for immunity to SARS-CoV-2 from epidemiological data series
        date: 2020-07-24
       words: 4974
      flesch: 47
     summary: Theoretical alternative approaches to detecting immunity would be desirable in these circumstances; and in principle identifying immunity times should be as simple as inferring the value of a free parameter by fitting an epidemiological model to field data. We then estimate the capacity of EAKF techniques to infer the duration of this memory and then apply this approach to mortality time series from New York City, discerning immunity times against SARS-CoV-2 with reasonable accuracy.
    keywords: data; epidemic; immunity; license; medrxiv; model; preprint
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        item: #2996 of 7819
          id: cord-289378-ghmqd3yv
      author: Wang, Peng-Wei
       title: Subjective Deterioration of Physical and Psychological Health during the COVID-19 Pandemic in Taiwan: Their Association with the Adoption of Protective Behaviors and Mental Health Problems
        date: 2020-09-18
       words: 6484
      flesch: 34
     summary: It is reasonable to hypothesize that the deterioration of psychological health is significantly associated with sleep problems and suicidal ideation that have become more prevalent during the COVID-19 pandemic, whether the deterioration of physical health is significantly associated with sleep problems and suicidal ideation bears further exploration. The impact of physical activity on psychological health during Covid-19 pandemic in Italy COVID-19 pandemic and its impact on mental health of healthcare professionals Social Learning Theory and the Health Belief Model Fear and the 2019-nCoV outbreak Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China The psychological impact of quarantine and how to reduce it: Rapid review of the evidence Anxiety, worry and cognitive risk estimate in relation to protective behaviors during the 2009 influenza A/H1N1 pandemic in Hong Kong: Ten cross-sectional surveys The Effects of Social Support on Sleep Quality of Medical Staff Treating Patients with Coronavirus Disease 2019 (COVID-19) in January and February 2020 in China Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: A web-based cross-sectional survey Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease A longitudinal study on the mental health of general population during the COVID-19 epidemic in China The impact of community psychological responses on outbreak control for severe acute respiratory syndrome in Hong Kong Human Factors Considerations in Using Personal Protective Equipment in the COVID-19 Pandemic Context: A Bi-national Survey Study Aggregated COVID-19 suicide incidences in India: Fear of COVID-19 infection is the prominent causative factor COVID-19-Related Information Sources and Their Relationships with Confidence of People in Coping with COVID-19: A Facebook Survey Study in Taiwan (Preprint) Changes in Sex Life among People in Taiwan during the COVID-19 Pandemic: The Roles of Risk Perception, General Anxiety, and Demographic Characteristics COVID-19-Related Factors Associated with Sleep Disturbance and Suicidal Thoughts among the Taiwanese Public: A Facebook Survey Psychosocial impact among the public of the severe acute respiratory syndrome epidemic in Taiwan Social support measurement Reliability and factorial structure of the Chinese version of the State-Trait Anxiety Inventory State Trait Anxiety Inventory: A Test Manual/Test Form Predictive validity of a five-item symptom checklist to screen psychiatric morbidity and suicide ideation in general population and psychiatric settings Development and verification of validity and reliability of a short screening instrument to identify psychiatric morbidity The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations Social media divide: Characteristics of emerging adults who do not use social network websites The Use of Facebook in Recruiting Participants for Health Research Purposes: A Systematic Review Social isolation during the COVID-19 pandemic can increase physical inactivity and the global burden of cardiovascular disease Using eHealth to Support COVID-19 Education, Self-Assessment, and Symptom Monitoring in the Netherlands: Observational Study COVID-19 related stress exacerbates common physical and mental pathologies and affects treatment (Review) Infodemic and Emerging Issues through a Data Lens: The Case of China Theoretical explanations for maintenance of behaviour change: A systematic review of behaviour theories Estudio de la relación del entorno psicosocial en la práctica deportiva de la mujer Prevalence and Predictors of Anxiety and Depression Symptoms during the COVID-19 Pandemic and Compliance with Precautionary Measures: Age and Sex Matter Public behavior change, perceptions, depression, and anxiety in relation to the COVID-19 outbreak © 2020 by the authors
    keywords: anxiety; covid-19; covid-19 pandemic; deterioration; health; pandemic; respondents; study
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        item: #2997 of 7819
          id: cord-289399-ij23mvma
      author: None
       title: Facing the future—what lessons could we learn from Covid-19?
        date: 2020-05-13
       words: 1185
      flesch: 49
     summary: The insights should contribute to understanding the impact of recent austerity policies on health inequalities. In the commentary (in the ethics collection) entitled 'Global health without justice or ethics', Venkatapuram 10 argues that the 'singular failure of philosophers and global health policy planners and practitioners has been our failure to create and engender moral motivation, a will-among those who are able-to prevent millions of human deaths and create conditions for good health within and across countries'.
    keywords: covid-19; future; health; pandemic
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        item: #2998 of 7819
          id: cord-289445-t9qnsddo
      author: Rocha, Breno Amaral
       title: Why it is crucial to maintain oral care for patients undergoing head and neck radiotherapy during the COVID-19 pandemic
        date: 2020-08-07
       words: 1174
      flesch: 41
     summary: key: cord-289445-t9qnsddo authors: Rocha, Breno Amaral; Mendes, Polianne Alves; Lima, Lucianne Maia Costa; Lima, Mateus Costa; Souza, Paulo Eduardo Alencar de; Grossmann, Soraya de Mattos Camargo; Souto, Giovanna Ribeiro; Horta, Martinho Campolina Rebello title: Why it is crucial to maintain oral care for patients undergoing head and neck radiotherapy during the COVID-19 pandemic date: 2020-08-07 journal: J Stomatol Oral Maxillofac Surg DOI: 10.1016/j.jormas.2020.07.009 sha: doc_id: 289445 cord_uid: t9qnsddo nan Second, guidance on the importance of strict oral hygiene and oral care to be followed during RT should be provided.
    keywords: cancer; care; patients
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        item: #2999 of 7819
          id: cord-289451-yjrh5l4u
      author: Xiao, Huidi
       title: Social Distancing among Medical Students during the 2019 Coronavirus Disease Pandemic in China: Disease Awareness, Anxiety Disorder, Depression, and Behavioral Activities
        date: 2020-07-14
       words: 4720
      flesch: 45
     summary: We studied the associations between COVID-19 distancing and the lives of public health students on anxiety [14] , depression, and other behaviors. We also examined the differences among public health students in two universities, Capital Medical University (CCMU) in Beijing, and Huazhong University of Science and Technology (HUST) in Wuhan, the early epicenter of the COVID-19 outbreak in China.
    keywords: anxiety; covid-19; depression; disorder; health; medical; students; survey; wuhan
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        item: #3000 of 7819
          id: cord-289476-8wh3hn0n
      author: Leiker, Brenna
       title: COVID - 19 BRIEF INTRODUCTION IN MENTAL HEALTH CONSIDERATIONS FOR HEALTH CARE WORKERS AND PATIENTS
        date: 2020-07-28
       words: 3756
      flesch: 42
     summary: Keep all used swabs away from the bulk swab container to avoid contamination. Do not use calcium alginate swabs or swabs with wooden shafts, as they may contain substances that inactivate some viruses and inhibit PCR testing.
    keywords: cdc; cov-2; covid-19; infection; patient; sars; specimen; swab; testing
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        item: #3001 of 7819
          id: cord-289490-u0f0zyad
      author: Lumba, Rishi
       title: Neonate Born to a Mother with a Diagnosis of Suspected Intra-Amniotic Infection versus COVID-19 or Both
        date: 2020-07-18
       words: 1446
      flesch: 36
     summary: Intra-amniotic infection, also known as chorioamnionitis or more recently as intra-amniotic infection and inflammation (Triple I) American College of Obstetricians and Gynecologists Clinical characteristics of coronavirus disease 2019 in China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study Evidence of SARS-CoV-2 infection in returning travelers from Wuhan, China Clinical outcome of 55 asymptomatic cases at the time of hospital admission infected with SARS-coronavirus-2 in Shenzhen, China Presumed asymptomatic carrier transmission of COVID-19 Universal screening for SARS-CoV-2 in women admitted for delivery Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy e authors declare that there are no conflicts of interest regarding the publication of this paper.
    keywords: cov-2; covid-19; infection; sars
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        item: #3002 of 7819
          id: cord-289496-d8ac6l6o
      author: Chen, Min
       title: The introduction of population migration to SEIAR for COVID-19 epidemic modelling with an efficient intervention strategy
        date: 2020-08-06
       words: 4224
      flesch: 49
     summary: the validity of SEIAR model by experimentation. Quarantine can keep people at a social distance,and then change contact rate.
    keywords: covid-19; epidemic; model; number; people; rate
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        item: #3003 of 7819
          id: cord-289498-6hf3axps
      author: Tull, Matthew T.
       title: The Prospective Influence of COVID-19 Affective Risk Assessments and Intolerance of Uncertainty on Later Dimensions of Health Anxiety
        date: 2020-08-12
       words: 5958
      flesch: 28
     summary: Results speak to the relevance of different risk factors for health anxiety during the COVID-19 pandemic and highlight targets for reducing health anxiety risk. Health anxiety is conceptualized as a dimensional variable (Taylor & Asmundson, 2004) , and moderate levels of health anxiety may be functional in the context of a pandemic, increasing motivation to engage in protective behaviors such as social distancing, hand washing, and wearing a mask when outside of the home.
    keywords: affective; anxiety; assessments; covid-19; health; health anxiety; illness; intolerance; risk; time; uncertainty
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        item: #3004 of 7819
          id: cord-289520-i6pv90s9
      author: Harris, Carlyn
       title: An evidence-based framework for priority clinical research questions for COVID-19
        date: 2020-03-31
       words: 4709
      flesch: 42
     summary: Three bibliographic databases were searched to identify clinical studies published on SARS-CoV and MERS-CoV in the outbreak setting. Overall, clinical characterisation studies commonly found bilateral involvement with ground glass opacity, though a range of presentations were reported [8] [9] [10] 15] .
    keywords: coronavirus; covid-19; health; mers; novel; outbreak; patients; research; sars; studies
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        item: #3005 of 7819
          id: cord-289522-7u3d6nfc
      author: Ebrahimi, Mina
       title: COVID-19 Patients: A Systematic Review and Meta-Analysis of Laboratory Findings, Comorbidities, and Clinical Outcomes Comparing Medical Staff versus the General Population
        date: 2020-10-17
       words: 2463
      flesch: 37
     summary: key: cord-289522-7u3d6nfc authors: Ebrahimi, Mina; Malehi, Amal Saki; Rahim, Fakher title: COVID-19 Patients: A Systematic Review and Meta-Analysis of Laboratory Findings, Comorbidities, and Clinical Outcomes Comparing Medical Staff versus the General Population date: 2020-10-17 journal: It has been reported in a case without typical COVID-19 clinical characteristics and laboratory results, that the virus was detected in the stool sample suggesting that suspected cases of COVID-19 where diarrhea was present but no laboratory abnormalities are observed should be considered for follow up COVID-19 testing [37] .
    keywords: coronavirus; covid-19; medical; patients; staff; studies
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        item: #3006 of 7819
          id: cord-289524-jw4i2ccd
      author: Rossi, Esther Diana
       title: International perspectives: Impact of the COVID‐19 pandemic on cytology
        date: 2020-04-07
       words: 515
      flesch: 47
     summary: Cytology laboratories also are being impacted by this pandemic in several ways. Therefore, it is critical for us to gain knowledge from cytology colleagues who have had early experience during the current crisis.
    keywords: covid-19; cytology
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        item: #3007 of 7819
          id: cord-289533-hip9qtu5
      author: Smulever, Anabella
       title: Thyroid cancer in the Era of COVID-19
        date: 2020-08-04
       words: 2824
      flesch: 36
     summary: Although these studies show the first experiences related to COVID-19 in patients with cancer, probably the heterogeneous types of cancer, stages, and treatments would not allow drawing definitive conclusions than can be assumed in thyroid cancer patients. Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19) Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology on behalf of the TERAVOLT investigators: COVID-19 in patients with thoracic malignancies (TERAVOLT): first results of an international Thyroid hormone action on innate immunity Modulating the function of the immune system by thyroid hormones and thyrotropin Review of the molecular and cellular mechanisms of action of glucocorticoids for use in asthma The sympathetic nerveean integrative interface between two supersystems: the brain and the immune system Opioid modulation of immune responses: effects on phagocyte and lymphoid cell populations Thyroid disease in the time of COVID-19 American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer Radioiodine-induced changes in lymphocyte subsets in patients with differentiated thyroid carcinoma Lindemann, Lymphocyte function following radioiodine therapy in patients with thyroid carcinoma Dynamic risk assessment in patients with differentiated thyroid cancer Suspicious cervical lymph nodes detected after thyroidectomy for papillary thyroid cancer usually remain stable over years in properly selected patients Hematologic toxicities in cancer patients treated with the multi-tyrosine kinase sorafenib: a meta-analysis of clinical trials A phase 2 and biomarker study of cabozantinib in patients with advanced cholangiocarcinoma A phase 1 study of lenvatinib, multiple receptor tyrosine kinase inhibitor Covid-19 outbreak In Northern Italy: first practical indications for radiotherapy departments Author contributions All authors contributed to the study conception and design.
    keywords: cancer; covid-19; disease; infection; patients; risk; thyroid
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        item: #3008 of 7819
          id: cord-289535-srrfr1es
      author: Tregoning, J. S.
       title: Vaccines for COVID‐19
        date: 2020-10-18
       words: 14346
      flesch: 38
     summary: Identity of blood and tissue leukocytes supporting in vitro infection New insights into the immunopathology and control of dengue virus infection Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus Immunization with modified vaccinia virus Ankara-based recombinant vaccine against severe acute respiratory syndrome is associated with enhanced hepatitis in ferrets Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection Molecular mechanism for antibodydependent enhancement of coronavirus entry A perspective on potential antibody-dependent enhancement of SARS-CoV-2 Is there an ideal animal model for SARS? Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase Caution urged on SARS vaccines Aged BALB/c mice as a model for increased severity of severe acute respiratory syndrome in elderly humans Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus Development of animal models against emerging coronaviruses: from SARS to MERS coronavirus Blocking transmission of Middle East respiratory syndrome coronavirus (MERS-CoV) in llamas by vaccination with a recombinant spike protein Humoral immunogenicity and efficacy of a single dose of ChAdOx1 MERS vaccine candidate in dromedary camels The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice SARS-CoV-2 infection in farmed minks, the Netherlands Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2 Reinfection could not occur in SARS-CoV-2 infected rhesus macaques Ethical guidelines for deliberately infecting volunteers with COVID-19 Human challenge studies to accelerate coronavirus vaccine licensure SARS-CoV-2 controlled human infection models: ethics, challenge agent production and regulatory issues Effect of dexamethasone in hospitalized patients with COVID-19 Criner GJet al, for the GSUSI. Clinical vaccine trials conventionally undergo four broad Phases, from early safety in small numbers of volunteers (Phase I) to wide-scale post-licensure monitoring (Phase IV).
    keywords: antibodies; antibody; cell; challenge; coronavirus; cov-2; covid-19; development; disease; dna; human; immune; immunity; infection; mers; mice; phase; protein; responses; rna; sars; spike; studies; syndrome; trials; vaccination; vaccine; virus
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        item: #3009 of 7819
          id: cord-289542-u86ujtur
      author: Razavian, Narges
       title: A validated, real-time prediction model for favorable outcomes in hospitalized COVID-19 patients
        date: 2020-10-06
       words: 8075
      flesch: 41
     summary: To be effective, solutions involving machine learning must 4, 5 (1) address a clearly defined use case that clinical leaders will champion and (2) motivate changes in clinical management based on model predictions. These expected differences in model variables and outcomes challenge the generalizability of any predictive model, which emphasized the importance of prospective validation.
    keywords: care; covid-19; data; green; model; patients; performance; prediction; rate; risk; score; set; time; validation; variables
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        item: #3010 of 7819
          id: cord-289550-b8f4a7o3
      author: Neuwirth, C.
       title: Investigating duration and intensity of Covid-19 social-distancing strategies
        date: 2020-04-29
       words: 3868
      flesch: 48
     summary: The Lancet COVID-19: Getting ahead of the epidemic curve by early implementation of social distancing Mathematical modeling of COVID-19 transmission and mitigation strategies in the population of Ontario The variability of critical care bed numbers in Europe Estimating the number of infections and the impact of non-pharmaceutical interventions on COVID-19 in 11 European countries The psychological impact of quarantine and how to reduce it: rapid review of the evidence. In this study, we present an exploratory and model-based systems analysis that is 29 aimed at investigating the application of social distancing strategies to Covid-19.
    keywords: april; care; covid-19; license; medrxiv; model; number; preprint
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        item: #3011 of 7819
          id: cord-289563-xdyaw1vg
      author: Tsioufis, Konstantinos
       title: Unveiling the mystery of “missing” emergencies in the era of COVID-19 pandemic: a generalized phenomenon with unclarified implications
        date: 2020-07-23
       words: 728
      flesch: 37
     summary: On the other hand, one could speculate that the reduced LVEF reflects missing cases with milder symptoms. It is reasonable to hypothesize that this could have affected the visiting rates in COVID-19 dedicated hospitals equally, if not more.
    keywords: cases; covid-19; pandemic
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        item: #3012 of 7819
          id: cord-289574-engwi8h3
      author: An, Peng-jiao
       title: Biochemical indicators of coronavirus disease 2019 exacerbation and the clinical implications
        date: 2020-05-23
       words: 3196
      flesch: 30
     summary: Unlike the cytokines profile of SARS patients, COVID-19 patients have a remarkable increase of anti-inflammatory cytokines IL-10 (Table 1) , which has been often seen in HLH patients in previous studies [61, 67, 68] . At the beginning of the epidemic, Huang et al reported that the plasma levels of IL2, IL7, GSCF, CXCL10, MCP1, MIP1A, and TNF-α were higher in COVID-19 patients in the intensive care unit (ICU) than those of COVID-19 patients outside the ICU
    keywords: cells; clinical; coronavirus; covid-19; cytokine; il-6; infection; patients; sars
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        item: #3013 of 7819
          id: cord-289575-2kxhav4q
      author: Kearsley, R.
       title: The COVID‐19 information pandemic: how have we managed the surge?
        date: 2020-06-02
       words: 1414
      flesch: 44
     summary: Since the outbreak of this pandemic, our e-mail inboxes, social media feeds and even general news outlets have become saturated with new guidelines, revisions of guidelines, new protocols and updated protocols, all subject to constant amendments. The COVID-19 pandemic is demonstrating that we are utilising social media as one of our main sources for the dissemination of medical information
    keywords: covid-19; guidelines; information; pandemic
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        item: #3014 of 7819
          id: cord-289588-n61gz7pi
      author: Samudrala, Pavan Kumar
       title: Virology, pathogenesis, diagnosis and in-line treatment of COVID-19
        date: 2020-07-17
       words: 3903
      flesch: 41
     summary: The Journal 849 of hospital infection Nsp3 of coronaviruses: Structures and functions of a 851 large multi-domain protein Functional assessment of cell entry and receptor 853 usage for SARS-CoV-2 and other lineage B betacoronaviruses Structure of SARS coronavirus spike 856 receptor-binding domain complexed with receptor Molecular immune pathogenesis and 862 diagnosis of COVID-19 Development and Clinical Application of 866 A Rapid IgM-IgG Combined Antibody Test for SARS-CoV-2 Infection Diagnosis Potential preanalytical and analytical 869 vulnerabilities in the laboratory diagnosis of coronavirus disease 2019 (COVID-19) Receptor usage and cell entry of porcine epidemic diarrhea coronavirus Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting 876 SARS-CoV-2 infection in vitro Overlapping and discrete aspects of the pathology and pathogenesis of the 879 emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV COVID-19 vaccines: knowing the unknown Neurological Manifestations of Hospitalized Patients with China: a retrospective case series study Coronavirus (COVID-19): managing stress and anxiety Trypsin Treatment Unlocks Barrier for Zoonotic Bat This The clinical symptoms of COVID-19 infection can be seen after 5 to 6 days of incubation 272 which mainly differs from age and immune system of the person.
    keywords: coronavirus; cov-2; covid-19; infection; novel; pathogenesis; patients; protein; sars; spike
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        item: #3015 of 7819
          id: cord-289612-4x5t4c5u
      author: Alsuliman, Tamim
       title: COVID-19 paraclinical diagnostic tools: Updates and future trends
        date: 2020-06-20
       words: 7370
      flesch: 45
     summary: Therefore, it may be important to routinely detect viral RNA in stool specimens of COVID-19 patients during the hospitalization and recovery stage, and to perform transmission-based precautions for patients until the negative conversion of viral RNA in feces. Probably, combining RNA and antibody detections may significantly improve the sensitivity of pathogenic diagnosis for COVID-19 patients (p < 0.001), even in the early phase of 1-week since onset (p = 0.007).
    keywords: assay; cases; coronavirus; cov-2; covid-19; diagnosis; disease; infection; patients; pcr; results; rna; rrt; sars; study
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        item: #3016 of 7819
          id: cord-289613-4ep4a3sn
      author: Zahra, Shaker A.
       title: International entrepreneurship in the post Covid world
        date: 2020-09-14
       words: 7106
      flesch: 37
     summary: The arrival of Covid, damage to international institutions, shifting ideologies and changing patterns of international operations have also disrupted international business networks, widely viewed as essential to innovation, learning, access to resources, international expansion, and opportunity recognition (Lorenz, Ramsey, & Richey, 2018; Pedersen, Soda, & Stea, 2019) . It will then discuss how these changes are likely to affect international new ventures (INVs), which could be independently owned or corporate sponsored, such as those created by MNEs (Cumming, Sapienza, Siegel, & Wright, 2009; Zahra, 2020) .
    keywords: business; changes; companies; covid; economies; entrepreneurship; global; institutions; invs; markets; ventures; world
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        item: #3017 of 7819
          id: cord-289647-14ba5sro
      author: Panuganti, Bharat A.
       title: Predicting COVID-19 Incidence Using Anosmia and Other COVID-19 Symptomatology: Preliminary Analysis Using Google and Twitter
        date: 2020-06-02
       words: 3223
      flesch: 40
     summary: To quantify the effect of mass media communications on the correlation between smell loss tweets, searches, and COVID-19 incidence, we excluded March 22 to March 24 to obtain new Spearman correlation coefficients. The correlation between COVID-19 incidence and searches pertaining smell loss (0.524) was less robust than searches about nonsmell symptoms (0.744) and COVID-19 (0.893).
    keywords: covid-19; google; incidence; loss; search; smell; twitter
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        item: #3018 of 7819
          id: cord-289655-umc2t7du
      author: Parohan, Mohammad
       title: Liver injury is associated with severe Coronavirus disease 2019 (COVID‐19) infection: a systematic review and meta‐analysis of retrospective studies
        date: 2020-05-09
       words: 1486
      flesch: 51
     summary: Current meta‐analysis of retrospective studies was done to summarize available findings on the association between liver injury and severity of COVID‐19 infection. Two reviewers (MP and AS) extracted the following data from the studies: author's name, publication year, study design, sample size, age and gender of patients, serum levels of AST, ALT, Albumin and Bilirubin and outcome assessment methods.
    keywords: covid-19; infection; liver; studies
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        item: #3019 of 7819
          id: cord-289684-rvbofsmb
      author: Fisher, Jennifer
       title: COVID-19 associated parotitis: A case report
        date: 2020-06-27
       words: 1092
      flesch: 35
     summary: key: cord-289684-rvbofsmb authors: Fisher, Jennifer; Monette, Derek L.; Patel, Krupa R.; Kelley, Brendan P.; Kennedy, Maura title: COVID-19 associated parotitis: A case report date: 2020-06-27 journal: Am J Emerg Med DOI: 10.1016/j.ajem.2020.06.059 sha: doc_id: At the time we evaluated this patient there were no reports of COVID-19 associated parotitis.
    keywords: covid-19; gland; parotitis
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        item: #3020 of 7819
          id: cord-289719-64ugdvfe
      author: Tenforde, Mark W.
       title: Characteristics of Adult Outpatients and Inpatients with COVID-19 — 11 Academic Medical Centers, United States, March–May 2020
        date: 2020-07-03
       words: 3172
      flesch: 41
     summary: Few studies have systematically collected data on COVID-19 patients from varied health care settings in the United States. A majority of COVID-19 patients reported working during the 2 weeks preceding illness, and few had the ability to telework, underscoring the need for enhanced measures to ensure workplace safety.
    keywords: cov-2; covid-19; outpatients; patients; sars; symptoms; testing
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        item: #3021 of 7819
          id: cord-289722-cc05jqb6
      author: Bendtsen Cano, Oliva
       title: COVID-19 Modelling: the Effects of Social Distancing
        date: 2020-03-30
       words: 2514
      flesch: 57
     summary: Day 55 is used for initiating social distancing since the simulations here showed 337 dead and 5486 sick consistent with reported numbers on 23 March 2020 when the United Kingdom initiated lockdown. A data-driven analysis in the early phase of the outbreak Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship Estimation of the asymptomatic ratio of novel coronavirus infections (COVID-19) Covid-19: identifying and isolating asymptomatic people helped eliminate virus in Italian village Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 R: A Language and Environment for Statistical Computing.
    keywords: license; number; people; preprint
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        item: #3022 of 7819
          id: cord-289760-tjqd1srq
      author: Prats-Uribe, A.
       title: Ethnicity, comorbidity, socioeconomic status, and their associations with COVID-19 infection in England: a cohort analysis of UK Biobank data
        date: 2020-05-08
       words: 2793
      flesch: 45
     summary: High body weight was also independently associated with COVID-19 infection risk, with an adjusted relative risk of 1.04 (1.02-1.05) per kg/m 2 increase in BMI. To our knowledge, this is the first study of the association between sociodemographics, ethnicity, and COVID-19 infection risk in the UK.
    keywords: covid-19; data; infection; participants; risk
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        item: #3023 of 7819
          id: cord-289763-jek2pd31
      author: Fisher, Kimberly A.
       title: Attitudes Toward a Potential SARS-CoV-2 Vaccine: A Survey of U.S. Adults
        date: 2020-09-04
       words: 4711
      flesch: 40
     summary: Evidence that these characteristics are predictive of vaccine hesitancy could be useful in targeting vaccine messaging and outreach to populations at risk for not being vaccinated. Our findings suggest that a multipronged approach may be needed in which trusted physicians promote vaccine uptake against a backdrop of innovative approaches and channels to combat vaccine misinformation, consistent with the body of literature of strategies to address vaccine hesitancy (39).
    keywords: characteristics; coronavirus; covid-19; health; influenza; intent; participants; vaccination; vaccine
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        item: #3024 of 7819
          id: cord-289825-9hpegqlh
      author: Lazarus, Gilbert
       title: Medical students in Indonesia: an invaluable living gemstone during coronavirus disease 2019 pandemic
        date: 2020-07-21
       words: 1064
      flesch: 28
     summary: key: cord-289825-9hpegqlh authors: Lazarus, Gilbert; Mangkuliguna, Ghea; Findyartini, Ardi title: Medical students in Indonesia: an invaluable living gemstone during coronavirus disease 2019 pandemic date: 2020-07-21 journal: Korean J Med Educ DOI: 10.3946/kjme.2020.165 sha: doc_id: 289825 cord_uid: 9hpegqlh nan Starting in late December 2019, coronavirus disease 2019 (COVID-19) has brought devastating impacts to global economy and health, infecting nearly seven million people across 215 countries and accounting for hundred thousands of deaths [1] . Despite evident loss in learning opportunities, medical students in Indonesia have turned this shortcoming into an advantage by volunteering in numerous activities.
    keywords: covid-19; pandemic; students
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        item: #3025 of 7819
          id: cord-289832-092dtzrd
      author: Villard, Orianne
       title: The Plasmatic Aldosterone and C-Reactive Protein Levels, and the Severity of Covid-19: The Dyhor-19 Study
        date: 2020-07-21
       words: 3950
      flesch: 35
     summary: In univariate analyses, aldosterone levels at inclusion were significantly higher in patients with severe clinical course (OS ≥ 5) (median (min-max), 304.7 (102.5-1360.1) pmol/L) as compared to those with mild or moderate course (OS ≤ 4) (102.5 (102.5-540.2) pmol/L) (p < 0.01). At inclusion, aldosterone levels were not clearly associated with a specific clinical status (p = 0.61) (Figure 2A) .
    keywords: aldosterone; covid-19; levels; manuscript; max; patients; reviewing; severity
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        item: #3026 of 7819
          id: cord-289852-4uxb70rh
      author: Kassem, Dina H.
       title: Mesenchymal Stem Cells and Their Extracellular Vesicles: A Potential Game Changer for the COVID-19 Crisis
        date: 2020-09-30
       words: 6972
      flesch: 34
     summary: Thus, harnessing the immunomodulatory properties of mesenchymal stem cells (MSCs) to ameliorate that cytokine-storm can indeed provide a golden key for the treatment of COVID-19 patients, especially severe cases. Antimicrobial activity of mesenchymal stem cells: current status and new perspectives of antimicrobial peptide-based therapies Immunopathology of SARS-CoV-2 infection: immune cells and mediators, prognostic factors, and immune-therapeutic implications Corticosteroid therapy for critically Ill patients with middle east respiratory syndrome Mesenchymal stromal cell infusion modulates systemic immunological responses in stable COPD patients: a phase I pilot study Expanded umbilical cord mesenchymal stem cells (UC-MSCs) as a therapeutic strategy in managing critically ILL COVID-19 patients: the case for compassionate use Mesenchymal stem/stromal cell secretome for lung regeneration: the long way through pharmaceuticalization for the best formulation Human Wharton's jelly mesenchymal stem cells show unique gene expression compared with bone marrow mesenchymal stem cells using single-cell RNA-sequencing Immunoinformatics-aided identification of T cell and B cell epitopes in the surface glycoprotein of 2019-nCoV Secretome of mesenchymal stromal cells prevents myofibroblasts differentiation by transferring fibrosis-associated microRNAs within extracellular vesicles Remdesivir for the treatment of covid-19 -preliminary report Extracellular vesicles, exosomes and shedding vesicles in regenerative medicine -a new paradigm for tissue repair International society for extracellular vesicles and international society for cell and gene therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19 Pathogenic role of HMGB1 in SARS?
    keywords: cells; cov-2; covid-19; cytokine; et al; immune; infection; lung; mesenchymal; mscs; patients; sars; stem; storm
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        item: #3027 of 7819
          id: cord-289854-p8okfa4b
      author: Flores, Gabriel
       title: Spontaneous Brainstem Hemorrhagic Stroke in the Setting of Novel Coronavirus Disease 2019 – A Case Report
        date: 2020-10-05
       words: 1427
      flesch: 38
     summary: Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Hemorrhagic stroke and anticoagulation in COVID-19 COVID-19 and cerebral hemorrhage: proposed mechanisms (IN PRESS) COVID-19 and intracerebral haemorrhage: causative or coincidental Novel coronavirus disease 2019 and subarachnoid hemorrhage: a case report Neuroradiological features in COVID-19 patients: first evidence in a complex scenario (IN PRESS) Aphasia and cerebral haemorrhage complicating whooping-cough SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Angiotensin converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system Intracerebral hemorrhage without a bleeding diathesis has been reported only rarely in COVID-19 patients [4] .
    keywords: covid-19; hemorrhage; patients; risk
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        item: #3028 of 7819
          id: cord-289855-11pkt4uu
      author: Bhargava, Shashank
       title: Employing dermatologists on the frontline against COVID‐19: All hands on deck
        date: 2020-05-13
       words: 347
      flesch: 45
     summary: Healthcare providers should be recruited in critical care management depending upon their skill set and confidence level. Low-resource countries with weakened healthcare systems are likely to become overwhelmed with a sudden surge of cases due to exponential growth and community transmission.
    keywords: healthcare
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        item: #3029 of 7819
          id: cord-289859-b1k9uyp6
      author: Hodges, Kevin
       title: Successful management of COVID‐19 and associated coagulopathy in a patient with durable left ventricular assist device
        date: 2020-08-13
       words: 1058
      flesch: 32
     summary: 4, 5 These findings have prompted interest in the use of anticoagulation for management and prophylaxis in COVID-19 patients. We describe our institutional protocol for managing COVID‐19 infection in patients on mechanical circulatory support, focusing on the need for a thoughtful, multidisciplinary approach.
    keywords: covid-19; infection; management; patients
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        item: #3030 of 7819
          id: cord-289873-6hivjqof
      author: Lu, Rui
       title: Patients with mild and general COVID-19 should be negative for at least 3 consecutive nucleic acid tests before discharged
        date: 2020-10-02
       words: 1693
      flesch: 46
     summary: Meanwhile, if COVID-19 patients who met other discharge criteria were tested for 3 consecutive nucleic acids (median test time was 23 days), the positive rate of nucleic acid test after three nucleic acid tests might be 5.26%. Patients met the following inclusion criteria were included in this study: (1) patients with mild and general COVID-19 [3] ; (2) Patients with complete self-care ability; (3) patients diagnosed with COVID-19 through nucleic acid test.
    keywords: acid; nucleic; patients
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        item: #3031 of 7819
          id: cord-289890-sf2uxubd
      author: Rushworth, S. A.
       title: Performance and health economic evaluation of the Mount Sinai COVID-19 serological assay identifies modification of thresholding as necessary to maximise specificity of the assay
        date: 2020-06-12
       words: 3956
      flesch: 46
     summary: To further understand the results from the two unexpected Mount Sinai assay SARS-CoV-2 IgG antibody positive patient samples from our auto-antibody control group, we next performed the SARS-CoV-2 IgG antibody assay using the same serum on our Abbott SARS-CoV-2 IgG system. Finally, we conducted a health economic probabilistic sensitivity analysis (PSA) on the costs of producing the tests, and the mean cost we estimate to be 13.63 pounds sterling (95%CI 9.63 - 18.40), allowing its cost effectiveness to be tested against other antibody tests.
    keywords: antibody; assay; cov-2; covid-19; patients; preprint; samples; sars; test
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        item: #3032 of 7819
          id: cord-289904-u3et3we5
      author: Martinez, G.S.
       title: Protect the vulnerable from extreme heat during the COVID-19 pandemic
        date: 2020-05-15
       words: 2356
      flesch: 32
     summary: Extreme heat causes significant mortality in the region every summer, with periodical peaks; the summer heatwaves of 2003 killed over 70,000 (Fouillet et al., 2008) and the combination of heat and wildfire smoke killed over 55,000 in Russia in 2010 (Barriopedro et al., 2011 ). Rapid surveillance systems are a core component of heat plans and have been introduced throughout Europe in recent years not only to monitor the health impacts of heatwaves but are considered a strategic tool for an effective public health response (Martinez et al., 2019; WHO, 2008) .
    keywords: covid-19; et al; health; heat; mortality; transmission
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        item: #3033 of 7819
          id: cord-289905-dvl2pud2
      author: Gan, Rosemary
       title: COVID-19 as a Viral Functional ACE2 Deficiency Disorder with ACE2 Related Multi-organ Disease
        date: 2020-06-23
       words: 4360
      flesch: 29
     summary: This group of patients may well carry higher risk for COVID-19 renal disease. The viral destruction of ACE2 expressing cells may lead to the profound loss of the protective AT(1-7) effects in an environment of ATII effect dominance (Fig. 1) .
    keywords: ace2; angiotensin; cells; covid-19; disease; patients; risk; sars; thrombosis
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        item: #3034 of 7819
          id: cord-289907-wzctqkd7
      author: Elimian, K. O.
       title: Descriptive epidemiology of coronavirus disease 2019 in Nigeria, 27 February–6 June 2020
        date: 2020-09-11
       words: 5019
      flesch: 48
     summary: A total of 40 926 persons (67% of total 60 839) had complete records of RT-PCR test across 35 states and the Federal Capital Territory, 12 289 (30.0%) of whom were confirmed COVID-19 cases. The highest proportion of COVID-19 cases and deaths were recorded in persons aged 31–40 years (25.5%) and 61–70 years (26.6%), respectively; and males accounted for a higher proportion of confirmed cases (65.8%) and deaths (79.0%).
    keywords: cases; covid-19; data; disease; health; nigeria; study
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        item: #3035 of 7819
          id: cord-289917-2mxd7zxf
      author: Singh, Brijesh P.
       title: Modeling tempo of COVID‐19 pandemic in India and significance of lockdown
        date: 2020-08-04
       words: 2756
      flesch: 52
     summary: In order to support the prevention of the disease and aid to the healthcare professionals, an attempt has been made to develop a simple model for the prediction of confirmed COVID-19 cases and to utilize that model for forecasting future COVID-19 cases in India. Further, time series models have been employed for predicting the incidence of COVID-19 disease.
    keywords: cases; covid-19; disease; india; lockdown; model; pandemic
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        item: #3036 of 7819
          id: cord-289919-iqa5pxda
      author: Deng, Shichang
       title: Perceived Severity of COVID-19 and Post-pandemic Consumption Willingness: The Roles of Boredom and Sensation-Seeking
        date: 2020-09-16
       words: 6556
      flesch: 45
     summary: A questionnaire modeling tested H1 and H2, which provided an aggregate survey of the relationship between perceived severity of COVID-19 and post-pandemic consumption willingness, as well as the mediators between them. First, we examined the differences of post-pandemic consumption willingness between demographic variables.
    keywords: boredom; consumption; covid-19; pandemic; people; seeking; sensation; severity; study
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        item: #3037 of 7819
          id: cord-289921-2x6011gr
      author: Aldarhami, Abdu
       title: Public Perceptions and Commitment to Social Distancing “Staying-at-Home” During COVID-19 Pandemic: A National Survey in Saudi Arabia
        date: 2020-09-22
       words: 4092
      flesch: 46
     summary: Notably, residents of the northern and southern parts of KSA presented a lower engagement with social distancing, which could be attributed to the delayed appearance of COVID-19 cases in those regions. Social distancing measures, such as stay-at-home, are currently implemented to control the COVID-19 pandemic in many countries, including Saudi Arabia.
    keywords: awareness; covid-19; distancing; home; participants; saudi; study
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        item: #3038 of 7819
          id: cord-290000-4ko413xm
      author: Singh, Awadhesh Kumar
       title: Editorial: Herd mentality, herds of migrants/people, and COVID-19 in India
        date: 2020-05-05
       words: 617
      flesch: 38
     summary: key: cord-290000-4ko413xm authors: Singh, Awadhesh Kumar; Misra, Anoop title: Editorial: Herd mentality, herds of migrants/people, and COVID-19 in India date: 2020-05-05 journal: Diabetes Metab Syndr DOI: 10.1016/j.dsx.2020.05.004 sha: doc_id: 290000 cord_uid: 4ko413xm nan This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. Mass gatherings continued during lockdown (e.g. herds of migrants returning to their native places from cities, herd of people gathering in religious assemblies, in meetings of 'super spreader' preachers [5] and clustering at marriage ceremonies) despite major spread of COVID-19 have been witnessed in other countries following such events.
    keywords: covid-19; herd
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        item: #3039 of 7819
          id: cord-290001-603qy8ml
      author: Pimentel, Lígia L.
       title: Cholesterol, inflammation, and phospholipids: COVID-19 share traits with cardiovascular disease
        date: 2020-10-17
       words: 1839
      flesch: 35
     summary: Thus, this research letter aims to present and discuss the current information about observed changes in lipid metabolites in COVID-19 patients. Interestingly, many research studies had reported that COVID-19 patients, previously presented comorbidities as type 2 diabetes mellitus, hypertension, and cardiovascular diseases (CVD)
    keywords: cells; covid-19; disease; patients; sars; system
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        item: #3040 of 7819
          id: cord-290040-29mmwi6z
      author: Mcloughlin, B. C.
       title: Functional and cognitive outcomes after COVID-19 delirium
        date: 2020-06-09
       words: 2150
      flesch: 43
     summary: key: cord-290040-29mmwi6z authors: Mcloughlin, B. C.; Miles, A.; Webb, T. E.; Knopp, P.; Eyres, C.; Fabbri, A.; Humphries, F.; Davis, D. title: Functional and cognitive outcomes after COVID-19 delirium date: 2020-06-09 journal: nan DOI: 10.1101/2020.06.07.20115188 sha: doc_id: 290040 cord_uid: 29mmwi6z Purpose To ascertain delirium prevalence and outcomes in COVID-19. Results In 71 patients, 31 (42%) had delirium, of which only 19 had been recognised by the clinical team.
    keywords: covid-19; delirium; medrxiv; patients; preprint
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        item: #3041 of 7819
          id: cord-290041-zxlq63n5
      author: Srivastava, Arnav
       title: Delaying Surgery for Clinical T1b-T2bN0M0 Renal Cell Carcinoma: Oncologic Implications in the COVID-19 Era and Beyond
        date: 2020-10-20
       words: 2996
      flesch: 45
     summary: The effect of surgical delay on kidney cancer outcomes has not been robustly evaluated. Specifically, we selected only those patients who underwent surgery to best model the effects of surgical delay on patients scheduled to receive surgery.
    keywords: delay; months; patients; staging; surgery; survival
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        item: #3042 of 7819
          id: cord-290053-2i0lqs12
      author: Wang, Weiping
       title: Radiotherapy after the easing of public restrictions during COVID-19 epidemic
        date: 2020-07-09
       words: 1326
      flesch: 41
     summary: Two hospitals in Wuhan reported that all new admitted patients are receiving COVID-19 screening, including blood test, chest CT, and nucleic acid test, before radiotherapy After the COVID-19 outbreak, there have been some reports on experiences or guidance on radiotherapy workflow and protection procedures for infection control zoning, area disinfection, personal protective equipment, staff rotation, COVID-19 screening, and emergence plans, among other measures [2] [3] [4] [5] [6] .
    keywords: covid-19; patients; radiotherapy; recommendations
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        item: #3043 of 7819
          id: cord-290057-tj97q2py
      author: Valdivia, Andrés Reyes
       title: Cardiovascular examination should also include peripheral arterial evaluation for COVID-19 patients
        date: 2020-04-30
       words: 621
      flesch: 42
     summary: The underdiagnoses in hospitalized patients could 21 be related to incomplete physical examinations in poorly communicating isolated elderly patients 22 (who may already have oxygen support and painkillers to treat high grade fever). Although substantial attention is directed toward evaluating the relationship between COVID-19 3 and myocardial disease 4,5 , we should not forget the global picture of the CV pathology and its 4 potential inducement of peripheral arterial disease (PAD).
    keywords: disease; patients
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        item: #3044 of 7819
          id: cord-290085-gsma97ja
      author: Satici, Begum
       title: Intolerance of Uncertainty and Mental Wellbeing: Serial Mediation by Rumination and Fear of COVID-19
        date: 2020-05-15
       words: 3974
      flesch: 37
     summary: First suicidal case in India! Introduction to mediation, moderation, and conditional process analysis: a regressionbased approach Intolerance of uncertainty mediates symptoms of PTSD and depression in African American veterans with comorbid PTSD and substance use disorders Further clarifying prospective and inhibitory intolerance of uncertainty: Factorial and construct validity of test scores from the intolerance of uncertainty scale The importance of the neighborhood in the 2014 Ebola outbreak in the United States: Distress, worry, and functioning Turkish version of the Warwick-Edinburgh Mental Well-Being Scale: A validity and reliability study Foundational frameworks of positive psychology: Therefore, within the framework of all these empirical findings, it can be concluded that rumination increases negative cognition and bad mood as well as negative psychological wellbeing in traumatic and uncertain situations.
    keywords: covid-19; fear; intolerance; rumination; uncertainty; wellbeing
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        item: #3045 of 7819
          id: cord-290116-ytpofa7b
      author: Sujath, R.
       title: A machine learning forecasting model for COVID-19 pandemic in India
        date: 2020-05-30
       words: 3558
      flesch: 53
     summary: Figure 5 shows the COVID-19 predicted confirmed cases; death cases and recovered cases based on actual confirmed, death and recovered data with a 95% CI with LR.The graph can be interpreted that cases are going to be increased in future as per the existing case data. Stochastic Environmental Research and Risk Assessment Figure 6 shows the COVID-19 predicted confirmed cases; death cases and recovered cases based on actual confirmed, death and recovered data with a 95% CI with MLP.
    keywords: cases; covid-19; data; death; figure; information; mlp; model
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        item: #3046 of 7819
          id: cord-290123-scd9u8ix
      author: Mustafa, Mujahed I.
       title: Cytokine Storm in COVID-19 Patients, Its Impact on Organs and Potential Treatment by QTY Code-Designed Detergent-Free Chemokine Receptors
        date: 2020-09-23
       words: 3559
      flesch: 38
     summary: The main advantage of QTY receptors is to serve as an antibody-like structure to decrease the excessive cytokine levels related with cytokine storm syndrome in COVID-19 infection. The novel coronavirus is not only causing respiratory problems, but it may also damage the heart, kidneys, liver, and other organs; in Wuhan, 14 to 30% of COVID-19 patients have lost their kidney function and now require either dialysis or kidney transplants.
    keywords: cells; coronavirus; covid-19; cytokine; disease; patients; qty; receptors; sars; storm
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        item: #3047 of 7819
          id: cord-290140-mmbzxz06
      author: Lord, Heidi
       title: Effective communication is key to ICU nurses willingness to provide nursing care amidst the COVID-19 pandemic
        date: 2020-10-01
       words: 2984
      flesch: 45
     summary: This study explores the willingness of ICU nurses to provide nursing care during the COVID-19 pandemic with the purpose of identifying the response of nursing staff to the pandemic and implementing support services to assist current and future pandemic response. Interestingly, the willingness of ICU nurses in our study to provide nursing care during the COVID-19 pandemic had no association with demographic factors.
    keywords: care; covid-19; icu; nurses; pandemic; study
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        item: #3048 of 7819
          id: cord-290195-8uaai9nv
      author: Stebbing, Justin
       title: Mechanism of baricitinib supports artificial intelligence‐predicted testing in COVID‐19 patients
        date: 2020-05-30
       words: 6616
      flesch: 39
     summary: Collectively, this limited case series provides preliminary evidence that baricitinib treatment may lower inflammatory burden and may result in a reduction in disease severity in COVID-19 patients. Following the recent publications by Stebbing et al.(Richardson et al., 2020a, Stebbing et al., 2020) , COVID-19 patients were treated with baricitinib in a pilot study in Milan, Italy.
    keywords: anti; baricitinib; cells; cov-2; covid-19; cytokine; data; disease; et al; fig; human; il-6; patients; sars; treatment
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        item: #3049 of 7819
          id: cord-290209-gkx57lyq
      author: Losurdo, Pasquale
       title: Impact of lockdown for SARS-CoV-2 (COVID-19) on surgical site infection rates: a monocentric observational cohort study
        date: 2020-09-14
       words: 4098
      flesch: 39
     summary: Care bundles and prevention of surgical site infection in colorectal surgery Intraoperative surgical site infection control and prevention: a position paper and future addendum to WSES intra-abdominal infections guidelines Effect of the application of a bundle of three measures (intraperitoneal lavage with antibiotic solution, fascial closure with Triclosan-coated sutures and Mupirocin ointment application on the skin staples) on the surgical site infection after elective laparoscopic colorectal cancer surgery Modification of the World Health Organization global guidelines for prevention of surgical site infection is needed Intraoperative interventions for preventing surgical site infection: an overview of Cochrane Reviews Knowledge, awareness, and attitude towards infection prevention and management among surgeons: identifying the surgeon champion 2018: a focus on surgical antibiotic prophylaxis prolongation A proposal for a comprehensive approach to infections across the surgical pathway A comprehensive updated review on SARS-CoV-2 and COVID-19 Cluster randomised controlled trial to examine medical mask use as source control for people with respiratory illness Societa Italiana di Anestesia Analgesia Rianimazione e Terapia Intensiva Airway Management Research G. Prevention is better than the cure, but the cure cannot be worse than the disease: fibreoptic tracheal intubation in COVID-19 patients The Italian coronavirus disease 2019 outbreak: recommendations from clinical practice Postoperative surgical site infections: understanding the discordance between surveillance systems CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting CDC definitions of nosocomial surgical site infections, 1992: a modification of CDC definitions of surgical wound infections Early arrhythmic events in idiopathic dilated cardiomyopathy Prognostic modeling with logistic regression analysis: in search of a sensible strategy in small data sets Confidence intervals after multiple imputation: combining profile likelihood information from logistic regressions An introduction to recursive partitioning: rationale, application, and characteristics of classification and regression trees, bagging, and random forests Strategies to prevent surgical site infections in acute care hospitals: 2014 update A randomized trial comparing skin antiseptic agents at cesarean delivery Discordance between perioperative antibiotic prophylaxis and wound infection cultures in patients undergoing pancreaticoduodenectomy Randomized controlled trial of two alcohol-based preparations for surgical site antisepsis in colorectal surgery Risk factors and prediction model for inpatient surgical site infection after major abdominal surgery A novel, validated risk score to predict surgical site infection after pancreaticoduodenectomy Impact of surgical site infection on healthcare costs and patient outcomes: a systematic review in six European countries Risk factors for superficial vs deep/organ-space surgical site infections: implications for quality improvement initiatives Surgical site infections after colorectal surgery: do risk factors vary depending on the type of infection considered? Updated recommendations for control of surgical site infections A statewide assessment of surgical site infection following colectomy: the role of oral antibiotics Mechanical bowel preparation for elective colorectal surgery. Surgical site infections (SSIs) are the most common in-hospital acquired infections, adding up to 46.4% of all infections, as reported by the CDC [1] .
    keywords: covid-19; era; infection; patients; risk; sars; site; ssis; study; surgery
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        item: #3050 of 7819
          id: cord-290256-mkfg7nar
      author: Ren, Zhigang
       title: A Randomized, Open‐label, Controlled Clinical Trial of Azvudine Tablets in the Treatment of Mild and Common COVID‐19, A Pilot Study
        date: 2020-07-14
       words: 4627
      flesch: 52
     summary: The preliminary results showed that FNC treatment in the mild and common COVID‐19 may shorten the NANC time versus standard antiviral treatment. Expect for FNC treatment and standard antiviral therapy, other treatments were symptomatic treatment according to the Diagnosis and treatment program trial version 5 (or 6) guidelines, and without additional treatments.
    keywords: acid; control; covid-19; fnc; fnc group; group; patients; treatment
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        item: #3051 of 7819
          id: cord-290267-ke696q8j
      author: Fang, Huilin
       title: Impact of comorbidities on clinical prognosis in 1280 patients with different types of COVID-19
        date: 2020-10-13
       words: 4882
      flesch: 39
     summary: Compared with ordinary patients, a significantly greater proportion of critical patients experienced cough (76.6% vs 65.6%, p<0.05), sputum production (28.2% vs 16 was significantly lower than that of ordinary and severe patients (25.0% vs 73.0%, 55.1%; p<0.05), and the cure rate of severe patients was also significantly lower than that of ordinary patients (73.0% vs 55.1%, p<0.05). In addition, the mortality rate of critical patients was significantly higher than that of ordinary and severe patients (47.6% vs 0.4%, 1.9%; p<0.05), and the mortality rate of severe patients was also significantly higher than that of ordinary patients (1.9% vs 0.4%, p<0.05).
    keywords: comorbidities; covid-19; diabetes; hypertension; p<0.05; patients; rate
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        item: #3052 of 7819
          id: cord-290295-gl144dh9
      author: Martínez-López, Joaquín
       title: Multiple myeloma and SARS-CoV-2 infection: clinical characteristics and prognostic factors of inpatient mortality
        date: 2020-10-19
       words: 4091
      flesch: 30
     summary: To our knowledge, this is the first large case-series study to describe comprehensively the clinical characteristics of COVID-19 in hospitalized MM patients, compare outcomes with a noncancer cohort of COVID-19 patients, and identify preadmission prognostic factors of inpatient mortality. Among MM patients, inpatient mortality was 41% in males, 42% in patients aged >65 years, 49% in patients with active/progressive MM at hospitalization, and 59% in patients with comorbid renal disease at hospitalization, which were independent prognostic factors on adjusted multivariate analysis.
    keywords: covid-19; disease; factors; hospital; inpatient; mortality; myeloma; noncancer; patients
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        item: #3053 of 7819
          id: cord-290297-efo9f7c5
      author: Vaillancourt, Mylene
       title: The Unrecognized Threat of Secondary Bacterial Infections with COVID-19
        date: 2020-08-07
       words: 1355
      flesch: 24
     summary: Bacterial coinfections are also present during regular influenza seasons in 2% to 65% of cases and are associated with morbidity and mortality (7) (8) (9) We are using more antibiotics in our fight to save COVID-19 patients from bacterial coinfections, and it is important to consider how this could affect the prevalence of antibiotic-resistant bacteria globally. The critically ill patients had the highest percentage of bacterial coinfection (34.5%) compared to patients in the moderately ill and severely ill groups (3.9% and 8.3%, respectively) (2).
    keywords: bacteria; coinfections; covid-19; patients
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        item: #3054 of 7819
          id: cord-290309-6i82ieim
      author: Zini, Gina
       title: Morphological anomalies of circulating blood cells in COVID‐19
        date: 2020-04-22
       words: 1011
      flesch: 32
     summary: China Intensive Care Med Characteristics of peripheral lymphocyte subset alteration in COVID-19 pneumonia Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Epidemiologic and clinical characteristics of 91 hospitalized patients with COVID-19 in Zhejiang, China: a retrospective, multi-centre case series Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Patients of COVID-19 may benefit from sustained lopinavir-combined regimen and the increase of eosinophil may predict the outcome of COVID-19 progression Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis Hematologic parameters in patients with COVID-19 infection Leukoerythroblastic reaction in a patient with COVID-19 infection Papa Giovanni XXIII Bergamo Hospital at the time of the COVID-19 outbreak: letter from the warfront Dysregulation of immune response in patients with COVID-19 in Wuhan, China COVID-19: consider cytokine storm syndromes and immunosuppression COVID-19 Illness in Native and Immunosuppressed States: A Clinical-Therapeutic Staging Proposal factor in the evolution of COVID-19 pneumonia. At Fondazione Policlinico A. Gemelli of Rome, a parallel COVID-19 hospital has been created to provide assistance to patients from the region of Lazio and central Italy.
    keywords: blood; cases; covid-19; patients
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        item: #3055 of 7819
          id: cord-290314-ldv9hsv1
      author: Cortis, Dominic
       title: On Determining the Age Distribution of COVID-19 Pandemic
        date: 2020-05-15
       words: 1554
      flesch: 55
     summary: This comment discusses the distribution of confirmed COVID-19 cases in relation to the population distribution for three studies. The percentage of youths with confirmed COVID-19 cases is far lower than the standard population percentage, even in South Korea where a larger proportion of tests were held.
    keywords: age; cases; covid-19
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        item: #3056 of 7819
          id: cord-290325-vozu14wg
      author: O’Brien, Ciara M.
       title: Collateral damage: the impact of the COVID-19 pandemic on acute abdominal emergency presentations
        date: 2020-08-20
       words: 2366
      flesch: 46
     summary: COVID-19 positive patients frequently have elevated liver enzymes of uncertain etiology; a recent study reported that greater than 50% of these patients had cholestasis on ultrasound 11 . Axial, coronal and sagittal contrast enhanced abdominal CT images from a 43 year old female who presented to the ED with a 5 day history of lower abdominal pain.
    keywords: abdominal; covid-19; pandemic; patients
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        item: #3057 of 7819
          id: cord-290326-umv0q4d7
      author: Stachowska, Ewa
       title: Nutritional Support in Coronavirus 2019 Disease
        date: 2020-06-12
       words: 5121
      flesch: 32
     summary: A meta-analysis conducted in ICU patients demonstrated that early enteral nutrition within 24 h of ICU admission reduced mortality compared with delayed enteral intake (odds ratio, 0.45; 95% CI, 0.21-0.95, p = 0.038) The data on nutritional support in COVID-19 patients is still elusive.
    keywords: body; care; coronavirus; covid-19; energy; icu; infection; nutrition; patients; protein; risk; therapy
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        item: #3058 of 7819
          id: cord-290341-ei768v4s
      author: Anstey, D. Edmund
       title: The cardiac intensive care unit and the cardiac Intensivist during the COVID-19 surge in New York City()
        date: 2020-07-03
       words: 4213
      flesch: 38
     summary: Further, if a high volume of COVID-19 patients are anticipated, efforts can be made to re-construct rooms to be negative pressure. This period has also seen an increase in the number of CICU patients present with primary non-cardiac illnesses but with underlying cardiac disease.
    keywords: cardiac; care; cicu; clinical; covid-19; pandemic; patients; team
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        item: #3059 of 7819
          id: cord-290372-vv47wnqk
      author: Zhang, Yufang
       title: Association of digestive symptoms with severity and mortality of COVID-19: A protocol for systematic review and meta-analysis
        date: 2020-10-23
       words: 2147
      flesch: 36
     summary: Gastrointestinal manifestations of SARS-CoV-2 infection and virus load in fecal samples from the Hong Kong Cohort and systematic review and meta-analysis Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan Clinical characteristics of non-ICU hospitalized patients with coronavirus disease 2019 and liver injury: A retrospective study Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis The liver injury and gastrointestinal symptoms in patients with Coronavirus Disease 19: a systematic review and meta-analysis Liver injury is associated with severe Coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of retrospective studies Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis Impacts of immunosuppression and immunodeficiency on COVID-19: a systematic review and meta-analysis The Newcastle-Ottawa Scale (NOS) for assessing the quality if nonrandomized studies in metaanalyses Measuring inconsistency in meta-analyses GRADE: an emerging consensus on rating quality of evidence and strength of recommendations The quality of evidence in Chinese metaanalyses needs to be improved The skills and experience of GRADE methodologists can be assessed with a simple tool Clinical characteristics of 54 medical staff with COVID-19: a retrospective study in a single center in Wuhan Risk factors associated with clinical outcomes in 323 COVID-19 hospitalized patients in Wuhan, China Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection COVID-19 in solid organ transplant recipients: initial report from the US epicenter Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Risk factors for severe COVID-19: evidence from 167 hospitalized patients in Anhui Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China Risk factors for disease severity, unimprovement, and mortality of COVID-19 patients in Wuhan, China Clinical characteristics of 161 cases of corona virus disease 2019 (COVID-19) in Changsha Clinical value of immune-inflammatory parameters to assess the severity of coronavirus disease SARS-CoV-2 induced diarrhoea as onset symptom in patient with COVID-19 Severity and Mortality associated with COPD and Smoking in patients with COVID-19: a rapid systematic review and meta-analysis The reporting characteristics and methodological quality of Cochrane reviews about health policy research. We will search PubMed, Embase, Web of Science, and the Cochrane Central Register of Controlled Trials (CENTRAL) to identify clinical studies using search terms coronavirus disease-19, coronavirus disease 2019, COVID-19, 2019-nCoV, novel corona virus, novel coronavirus, new coronavirus, nCoV-2019, novel coronavirus pneumonia, 2019 novel coronavirus, severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, clinical characteristic, clinical feature, risk factor, prognosis, nausea, vomiting, diarrhea, digestive symptom, and gastrointestinal symptom.
    keywords: analyses; covid-19; meta; patients; studies; symptoms
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        item: #3060 of 7819
          id: cord-290392-kpjp0sx4
      author: Li, Xu
       title: Acute respiratory failure in COVID-19: is it “typical” ARDS?
        date: 2020-05-06
       words: 2579
      flesch: 45
     summary: Since severe COVID-19 patients may deteriorate rapidly, patients receiving HFNO should be closely monitored and cared for by experienced personnel capable of endotracheal intubation at any time. It was possible that due to less damage to the endothelial cells, other organ functions were less involved in COVID-19 patients.
    keywords: ards; coronavirus; covid-19; patients; treatment
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        item: #3061 of 7819
          id: cord-290419-angcz55b
      author: Tran, Bach Xuan
       title: Impact of COVID-19 on Economic Well-Being and Quality of Life of the Vietnamese During the National Social Distancing
        date: 2020-09-11
       words: 4612
      flesch: 41
     summary: In terms of COVID-19 impact on household income, a recent survey in late March 2020 with 7,005 respondents from G7 countries has indicated that 31% of participants reported that Coronavirus has already impacted my household income and 39% thought that Coronavirus has not yet impacted my household income, but I expect it to in the future (Duffin, 2020) . A study in Italy using a questionnaire to measure Health-Related Quality of Life (HRQOL) of Adults with Common Variable Immune Deficiency (CVID_QOL) has illustrated that COVID-19 disease generated negative effects on health-related quality of life and the risk of anxiety/depression among Primary Antibody Deficiencies patients (Pulvirenti et al., 2020) .
    keywords: covid-19; health; household; impact; income; life; people; quality; study; vietnam
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        item: #3062 of 7819
          id: cord-290428-zrlqzbss
      author: de Faria Coelho-Ravagnani, Christianne
       title: Dietary recommendations during the COVID-19 pandemic
        date: 2020-07-12
       words: 6421
      flesch: 39
     summary: Furthermore, water intake comes mostly from beverages (about 75%) and food intake (about 25%), especially from fresh food such as fruits and vegetables. Consume other foods of animal origin in moderation; Consume nuts, seeds, and olive oil; Avoid processed foods and fast food NA NA ASBRAN (2020) 13
    keywords: covid-19; diet; disease; food; fruits; guidelines; health; immune; nutrition; pandemic; risk; vegetables; vitamin; water; zinc
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        item: #3063 of 7819
          id: cord-290429-0d34abdo
      author: Elengoe, Asita
       title: COVID-19 Outbreak in Malaysia
        date: 2020-06-17
       words: 1336
      flesch: 52
     summary: The Star Malaysia Braces for Coronavirus Infections to Peak in Mid Cases in Malaysia 'likely to peak soon The Straits Times COVID-19: Increase of total cases are not the 'third wave' -Health DG COVID-19: MOH detects new cluster in Sendayan The origin, transmission, and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak -An update on the status A review of coronavirus disease-2019 (COVID-19) Coronavirus disease (COVID-2019) situation reports Clinical Virology An overview of their replication and pathogenesis Human coronaviruses: A review of virus-host interactions Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV ViPR: An open bioinformatics database and analysis resource for virology research Detection and full genome characterization of two beta CoV viruses related to Middle East respiratory syndrome from bats in Italy Systematic comparison of two animal-to-human transmitted human coronaviruses: SARS-CoV-2 and SARS-CoV Differences and similarities between Severe Acute Respiratory Syndrome (SARS)-CoronaVirus (CoV) and SARS-CoV-2. Would a rose by another name smell as sweet? From SARS to MERS, thrusting coronaviruses into the spotlight Epidemiology, causes, clinical manifestation and diagnosis, prevention, and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review COVID-19: A new challenge for human beings Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and myths Learning from the past: possible urgent prevention and treatment options for severe acute respiratory infections caused by 2019-nCoV Drug treatment options for the 2019-new coronavirus (2019-nCoV) Chloroquine, and hydroxychloroquine in the treatment of COVID-19 with or without diabetes: a systematic search and a narrative review with a special reference to India and other developing countries Covid-19 (Maklumat Terkini).
    keywords: cases; coronavirus; covid-19; malaysia; sars
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        item: #3064 of 7819
          id: cord-290456-cgrn5c36
      author: Soliman, Mohamed A. R.
       title: Endoscopic endonasal skull base surgery during the COVID-19 pandemic: A developing country perspective
        date: 2020-09-25
       words: 4110
      flesch: 42
     summary: Now in the midst of the pandemic, health-care facilities in developing countries are overwhelmed by COVID-19 patients. [38] In positive COVID-19 patients, all health-care personnel that dealt with the patient should be quarantined for 14 days.
    keywords: care; chest; countries; covid-19; health; pandemic; patients; pcr; surgery
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        item: #3065 of 7819
          id: cord-290458-5fwbh9t9
      author: Lal, Preet
       title: The dark cloud with a silver lining: Assessing the impact of the SARS COVID-19 pandemic on the global environment
        date: 2020-05-08
       words: 3716
      flesch: 39
     summary: Our study projects an increasing coverage of high COVID-19 hazard at absolute humidity levels ranging from 4 to 9 g m−3 across a large part of the globe during April–July 2020 due to a high prospective meteorological suitability for COVID-19 spread. The study projected an increasing coverage of high COVID-19 hazard in a large part of the globe during April to July 2020 due to high prospective meteorological suitability (AH: 4 to 9 g m -3 ).
    keywords: cases; coronavirus; covid-19; regions
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        item: #3066 of 7819
          id: cord-290471-xg9d4dex
      author: Coleman, Brian C
       title: Adapting to disruption of research during the COVID-19 pandemic while testing nonpharmacological approaches to pain management
        date: 2020-09-04
       words: 3975
      flesch: 30
     summary: Polytrauma clinical triad The musculoskeletal diagnosis cohort: Examining pain and pain care among veterans Persistent pain and comorbidity among Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn veterans Chronic pain and sleep disturbances: A pragmatic review of their relationships, comorbidities, and treatments Managing patients with chronic pain during the COVID-19 outbreak: Considerations for the rapid introduction of remotely supported (eHealth) pain management services NIH-DoD-VA pain management collaboratory Practical clinical trials: increasing the value of clinical research for decision making in clinical and health policy Integrating health research into disaster response: The new NIH disaster research response program The psychological impact of quarantine and how to reduce it: rapid review of the evidence Healthy people 2020 Interactive voice response-based self-management for chronic back pain: Sudden changes in the delivery of pain management interventions will probably alter treatment effects measured via PMC PCTs.
    keywords: care; covid-19; health; management; pain; pandemic; pcts; pmc; research; treatment
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        item: #3067 of 7819
          id: cord-290490-u3mkfvxw
      author: Armstrong-James, Darius
       title: Confronting and mitigating the risk of COVID-19 Associated Pulmonary Aspergillosis (CAPA)
        date: 2020-07-23
       words: 2299
      flesch: 20
     summary: Although performance might be superior to serum Aspergillus antigen testing for the detection of IPA in the ICU (28), BDG negativity cannot be used to rule out infection, with a 77% sensitivity determined across a heterogeneous population of IA patients, and performance in CAPA as yet to be determined. Fungal infections present an additional threat in the challenging task of managing COVID-19 patients in outbreak conditions.
    keywords: aspergillosis; bal; capa; covid-19; patients; pulmonary
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        item: #3068 of 7819
          id: cord-290500-v2n8godx
      author: Cardinali, Daniel P.
       title: Elderly as a High-risk Group during COVID-19 Pandemic: Effect of Circadian Misalignment, Sleep Dysregulation and Melatonin Administration
        date: 2020-09-26
       words: 3557
      flesch: 30
     summary: It involves adequate sleep hygiene, timed light exposure, and the use of a chronobiotic medication like melatonin, which affects the output phase of circadian rhythms thus controlling the biological clock. Chronotherapy is designed to restore the proper circadian pattern of the sleep-wake cycle in the elderly, through adequate sleep hygiene, timed light exposure, and the use of a chronobiotic medication like melatonin, that affects the output phase of circadian rhythms thus controlling the clock (Fig. 1) .
    keywords: aging; covid-19; light; melatonin; pandemic; rhythms; scn; sleep; system
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        item: #3069 of 7819
          id: cord-290522-icjt8bbw
      author: Sablerolles, Roos S G
       title: COvid MEdicaTion (COMET) study: protocol for a cohort study
        date: 2020-06-25
       words: 2382
      flesch: 39
     summary: Due to the urgency of need of this data, time to enter clinical data will be limited, potentially leading to incomplete data, especially the medical history. Eur J Hosp Pharm DOI: 10.1136/ejhpharm-2020-002329 sha: doc_id: 290522 cord_uid: icjt8bbw Various theories about drugs such as ACE inhibitors or angiotensin II receptor blockers (ARBs) in relation to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and clinical outcomes of COVID-19 are circulating in both mainstream media and medical literature.
    keywords: ace; angiotensin; covid-19; data; inhibitors; patients
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        item: #3070 of 7819
          id: cord-290523-pqah68j8
      author: Waite, Roberta
       title: Effects of COVID-19 on the Mental Health of Black and Brown Racialized Populations in the U.S
        date: 2020-10-22
       words: 1040
      flesch: 47
     summary: This should not be a matter of if you pay, then you can play, but a best practices model of incorporating the major social determinants of health into assessment and treatment services for all needing health services, now during the pandemic and afterward. Racial diversity has greatly increased in the U.S., and the needs of our diverse population should inform health care practices and policy making in order to preclude disparities in these determinants, as well as the healthcare inequities that persist most pointedly along racial lines.
    keywords: care; covid-19; health; services
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        item: #3071 of 7819
          id: cord-290551-a02tueuu
      author: Singh, Shailendra
       title: Impact of Obesity on Outcomes of Patients with COVID-19 in United States: A Multicenter Electronic Health Records Network Study.
        date: 2020-08-21
       words: 2720
      flesch: 49
     summary: Our study using a large nationally representative database showed that COVID-19 patients with any degree of obesity had a significantly higher risk of hospitalization and intubation or death compared to patients without obesity. Advanced age and male gender are major risk factors for worse prognosis and higher mortality in COVID-19 patients 6 .
    keywords: covid-19; data; diagnosis; group; obesity; patients; risk
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        item: #3072 of 7819
          id: cord-290590-cmmkfokm
      author: Lee, Se Yoon
       title: Estimation of COVID-19 spread curves integrating global data and borrowing information
        date: 2020-04-29
       words: 7010
      flesch: 58
     summary: There are three major classes of infectious disease prediction models: (i) differential equation models, (ii) time series models, and (iii) the statistical models. On the other hand, statistical models which follow the laws of epidemiology (Clayton and Hills, 2013; Thompson et al., 2006) are also popular, and can be easily extended in the framework of hierarchical models (multilevel model) to analyze data within a nested hierarchy, eventually harnessing the data integration (Browne et al., 2006; Hill, 1965; Stone and Springer, 1965; Tiao and Tan, 1965) .
    keywords: april; countries; country; covid-19; curve; data; infection; model; preprint; total; trajectory
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        item: #3073 of 7819
          id: cord-290592-c9bsielo
      author: Wang, Rui
       title: The vitamin D for COVID-19 (VIVID) trial: A pragmatic cluster-randomized design
        date: 2020-10-10
       words: 4956
      flesch: 38
     summary: An association of serum vitamin D concentrations < 40 nmol/L with acute respiratory tract infection in young Finnish men Vitamin D status and acute lower respiratory J o u r n a l P r e -p r o o f infection in early childhood in Sylhet Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and metaanalysis of individual participant data Randomized trial of vitamin D supplementation and risk of acute respiratory infection in Mongolia Vitamin D3 supplementation in patients with frequent respiratory tract infections: a randomised and double-blind intervention study Vitamin D3 and gargling for the prevention of upper respiratory tract infections: a randomized controlled trial Effect of monthly high-dose vitamin D supplementation on acute respiratory infections in older adults: A randomized controlled trial Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the VIDARIS randomized controlled trial Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study COVID-19 infection: the perspectives on immune responses Vitamin D status of HIV-infected women and its association with HIV disease progression, anemia, and mortality Vitamin D and the immune system Vitamin D and Inflammation: Potential Implications for Severity of Covid-19 Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the Vitamin D supplementation could possibly improve clinical outcomes of patients infected with coronavirus-2019 (COVID-19) SSRN Patterns of COVID-19 mortality and vitamin D: An Indonesian Study Longitudinal data analysis for discrete and continuous outcomes Household secondary attack rate of COVID-19 and associated determinants in Guangzhou, China: a retrospective cohort study Secondary Attack Rate of COVID-19 in household contacts: Systematic review Identification of Antiviral Drug Candidates against SARS-CoV-2 from FDA-Approved Drugs Designing Clinical Trials That Accept New Arms: An Example in Metastatic Breast Cancer Effects of vitamin D supplementation on strength, physical performance, and falls in older persons: a systematic review The tolerability and biochemical effects of high-dose bolus vitamin D2 and D3 supplementation in patients with vitamin D insufficiency Annual high-dose oral vitamin D and falls and fractures in older women: a randomized controlled trial Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: Ecologic and demographic data also provide support for a protective role of vitamin D studies [28, 29] .
    keywords: covid-19; household; infection; respiratory; study; supplementation; treatment; vitamin
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        item: #3074 of 7819
          id: cord-290594-dvco042c
      author: Sofia, Soccorsa
       title: Thoracic ultrasound and SARS-COVID-19: a pictorial essay
        date: 2020-04-16
       words: 1626
      flesch: 33
     summary: Part 1: US findings and techniques Lung ultrasound in diagnosing pneumonia in childhood: a systematic review and metaanalysis Not all abolished lung slidings are pneumothorax: the case of a particular lung atelectasis Transthoracic ultrasound in children Diffusion and practice of ultrasound in emergency medicine departments in Italy Lung ultrasound in diagnosing pneumonia in the emergency department: a systematic review and meta-analysis Early recognition of the 2009 pandemic influenza A (H1N1) pneumonia by chest ultrasound Can lung US help critical care clinicians in the early diagnosis of novel coronavirus (COVID-19) Pneumonia? Lung ultrasound in communityacquired pneumonia and in interstitial lung diseases From an abdominal ultrasound to a lung disease passing through the diaphragm: a case of idiopathic pulmonary fibrosis Physical mechanisms providing clinical information from ultrasound lung images: hypotheses and early confirmations The role of ultrasound lung artifacts in the diagnosis of respiratory diseases Clinical use and barriers of thoracic ultrasound: a survey of italian pulmonologists Effects of positive end-expiratory pressure/recruitment manoeuvres compared with zero endexpiratory pressure on atelectasis during open gynaecological surgery as assessed by ultrasonography: a randomised controlled trial Ultrasound evaluation of diaphragmatic mobility in patients with idiopathic lung fibrosis: a pilot study Neonatal and pediatric thoracic ultrasonography Informed consent Informed consent to publish figures was obtained from patients. The use of lung ultrasound images for the differential diagnosis of pulmonary and cardiac interstitial pathology Bedside US imaging in multiple trauma patients.
    keywords: covid-19; lung; patients; pneumonia; ultrasound
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        item: #3075 of 7819
          id: cord-290611-fhaguv3f
      author: Ghio, Stefano
       title: Cardiac involvement at presentation in patients hospitalized with COVID-19 and their outcome in a tertiary referral hospital in Northern Italy
        date: 2020-09-22
       words: 3763
      flesch: 38
     summary: key: cord-290611-fhaguv3f authors: Ghio, Stefano; Baldi, Enrico; Vicentini, Alessandro; Lenti, Marco Vincenzo; Di Sabatino, Antonio; Di Matteo, Angela; Zuccaro, Valentina; Piloni, Davide; Corsico, Angelo; Gnecchi, Massimiliano; Speciale, Francesco; Sabena, Anna; Oltrona Visconti, Luigi; Perlini, Stefano title: Cardiac involvement at presentation in patients hospitalized with COVID-19 and their outcome in a tertiary referral hospital in Northern Italy date: 2020-09-22 journal: Intern Emerg Med DOI: 10.1007/s11739-020-02493-y sha: doc_id: 290611 cord_uid: fhaguv3f The correlation between myocardial injury and clinical outcome in COVID-19 patients is gaining attention in the literature. This datum, together with the observation that patients with elevated hs-TnI values at admission had laboratory and respiratory function data indicative of a more severe systemic infection, would support hypothesis that the increase of hs-TnI levels in COVID-19 patients is mainly the consequence of a more severe systemic disease rather being indicative of primary cardiac injury, as already described in the literature [19] .
    keywords: covid-19; hospital; patients; tni; values
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        item: #3076 of 7819
          id: cord-290619-e4h47fo4
      author: Castiglioni, Massimo
       title: SURGICAL RESECTIONS OF SUPERINFECTED PNEUMATOCELES IN A COVID-19 PATIENT
        date: 2020-06-27
       words: 884
      flesch: 37
     summary: Ann Thorac Surg DOI: 10.1016/j.athoracsur.2020.06.008 sha: doc_id: 290619 cord_uid: e4h47fo4 ABSTRACT Emerging studies on radiological findings in COVID-19 patients report a high incidence of bilateral lung involvement, with GGOs imaging being the most common pattern on CT. We report a case of a COVID-19 patient successfully treated by lung resections for infected pneumatoceles.
    keywords: covid-19; lung; pneumatoceles
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        item: #3077 of 7819
          id: cord-290636-x8cevt8d
      author: Ruiz-Quinonez, J. A.
       title: Features of patients that died for COVID-19 in a Hospital in the south of Mexico: A observational cohort study
        date: 2020-09-23
       words: 1538
      flesch: 52
     summary: A systematic review and meta-analysis of 148 studies 301 from 9 countries Diabetes mellitus is associated with increased 303 mortality and severity of disease in COVID-19 pneumonia -A systematic review, 304 meta-analysis, and meta-regression Hypertension is 307 associated with increased mortality and severity of disease in COVID-19 pneumonia: key: cord-290636-x8cevt8d authors: Ruiz-Quinonez, J. A.; Guzman-Priego, C.; Nolasco-Rosales, G. A.; Tovilla-Zarate, C. A.; Flores-Barrientos, O. I.; Narvaez-Osorio, V.; Baeza-Flores, G. d. C.; Gonzalez-Castro, T. B.; Lopez-Brito, C. R.; Denis-Garcia, C. A.; Perez-Garcia, A.; Juarez-Rojop, I. E. title: Features of patients that died for COVID-19 in a Hospital in the south of Mexico: A observational cohort study date: 2020-09-23 journal: nan DOI: 10.1101/2020.09.21.20199117 sha: doc_id: 290636 cord_uid: x8cevt8d Background: Due to the wide spread of SARS-CoV2 around the world, the risk of death in individuals with metabolic comorbidities has dangerously increased.
    keywords: author; medrxiv; preprint; review
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        item: #3078 of 7819
          id: cord-290642-vlyingsf
      author: Kwon, S.
       title: Association of social distancing and masking with risk of COVID-19
        date: 2020-11-13
       words: 5478
      flesch: 41
     summary: To minimize any variation of estimated daily social distancing grade associated with day of the week (e.g. Sunday vs. Monday), we used a seven-day average of community social distancing grade as the exposure for each participant. We first examined the latency between community social distancing grade and predicted COVID-19 using varying lag times (0 days, 7 days, 14 days, 21 days, and 28 days).
    keywords: covid-19; distancing; grade; license; mask; medrxiv; participants; preprint; risk; study
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        item: #3079 of 7819
          id: cord-290653-48swl1aq
      author: Teng, Margaret
       title: Endoscopy during COVID-19 pandemic: An overview of infection control measures and practical application
        date: 2020-09-16
       words: 2774
      flesch: 42
     summary: Standard cleaning and disinfection of endoscopy rooms and endoscopy equipment should continue. Post procedure Standard cleaning and disinfection of endoscopy rooms continue.
    keywords: cases; covid-19; endoscopy; pandemic; patients; procedures
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        item: #3080 of 7819
          id: cord-290677-3gdcyrrz
      author: De Virgiliis, Francesco
       title: Lung innervation in the eye of a cytokine storm: neuroimmune interactions and COVID-19
        date: 2020-08-25
       words: 6117
      flesch: 22
     summary: These cells show distinct transcriptional signatures, including CD169 + CD11c − and MHCII hi , as well as high expression of genes involved in communication with nerve cells, such as C1q and CX3CR1. This, in turns, disrupts mitochondrial metabolism and results in permanent neurolysis, making this drug potentially toxic for nerve cells and pulmonary neuroimmune homeostasis.
    keywords: cells; covid-19; fibres; immune; infection; lung; nerve; patients; receptor; response; sars; vagus; virus
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        item: #3081 of 7819
          id: cord-290694-jmav8xi4
      author: Bridgland, Victoria M. E.
       title: Why the COVID-19 pandemic is a traumatic stressor
        date: 2020-09-22
       words: 1104
      flesch: 46
     summary: key: cord-290694-jmav8xi4 authors: Bridgland, Victoria M. E.; Moeck, Ella K.; Green, Deanne M.; Swain, Taylor L.; Nayda, Diane; Matson, Lucy A.; Hutchison, Nadine P.; Takarangi, Melanie K.T. title: Why the COVID-19 pandemic is a traumatic stressor date: 2020-09-22 journal: bioRxiv DOI: 10.1101/2020.09.22.307637 sha: doc_id: 290694 cord_uid: jmav8xi4 The COVID-19 pandemic does not fit into prevailing Post-traumatic Stress Disorder (PTSD) models, or diagnostic criteria, yet emerging research shows traumatic stress symptoms as a result of this ongoing global stressor. The PTSD 531 Checklist for DSM-5 (PCL-5) Post-traumatic stress disorder and 533 psychological distress in Chinese youths following the COVID-19 emergency At what sample size do correlations stabilize?
    keywords: covid-19; participants; stress
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        item: #3082 of 7819
          id: cord-290712-flj352ql
      author: Bi, Jianping
       title: Does Chemotherapy Reactivate SARS-CoV-2 in Cancer Patients Recovered from Prior COVID-19 Infection?
        date: 2020-09-04
       words: 1347
      flesch: 38
     summary: key: cord-290712-flj352ql authors: Bi, Jianping; Ma, Hong; Zhang, Dongsheng; Huang, Jing; Yang, Dongqin; Wang, Yajie; Verma, Vivek; Zhang, Tao; Hu, Desheng; Mei, Qi; Han, Guang; Li, Jian title: Does Chemotherapy Reactivate SARS-CoV-2 in Cancer Patients Recovered from Prior COVID-19 Infection? date: 2020-09-04 journal: Eur Respir J DOI: 10.1183/13993003.02672-2020 sha: doc_id: 290712 cord_uid: flj352ql Recovered COVID-19 cancer patients remain negative for SARS-CoV-2 after delivery of chemotherapy To the Editor: Cancer patients are particularly vulnerable to coronavirus disease 2019 (COVID-19) (1) (2) (3) . To our knowledge, this is the first study reporting that recovered COVID-19 cancer patients remain negative in the short-term for SARS-CoV-2 after delivery of chemotherapy.
    keywords: chemotherapy; covid-19; patients
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        item: #3083 of 7819
          id: cord-290731-xp7pgbkd
      author: Balmforth, D.
       title: Cardiothoracic Surgery in the Midst of a Pandemic: Operative outcomes and maintaining a COVID-19-free environment.
        date: 2020-09-23
       words: 1689
      flesch: 44
     summary: Operative mortality was 9% in the cardiac patients and 1.4% in thoracic patients. However, there remains a need to provide cardiac surgery for urgent and emergency cases as 88 well as time-critical thoracic cancer surgery.
    keywords: cardiac; covid-19; patients; surgery
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        item: #3084 of 7819
          id: cord-290740-vt4txzfx
      author: Zhang, H.
       title: Challenges and Measures in Prevention of Nosocomial Infection of COVID‐19 During Resumption of Work: Experience from a Pancreatic Surgery Department, Wuhan, China
        date: 2020-08-24
       words: 620
      flesch: 52
     summary: In the fight against potential COVID-19 future outbreaks, infection-prevention strategies should be highly valued. The rapid spread of COVID-19 heavily increases health care systems burden worldwide and led to a postponement of nearly all elective procedures [2] [3] [4] [5] .
    keywords: covid-19; supplemental
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        item: #3085 of 7819
          id: cord-290766-aoyvdyra
      author: Brancalion, Pedro H.S.
       title: Emerging threats linking tropical deforestation and the COVID-19 pandemic
        date: 2020-09-30
       words: 2464
      flesch: 28
     summary: key: cord-290766-aoyvdyra authors: Brancalion, Pedro H.S.; Broadbent, Eben N.; de-Miguel, Sergio; Cardil, Adrián; Rosa, Marcos R.; Almeida, Catherine T.; Almeida, Danilo R.A.; Chakravarty, Shourish; Zhou, Mo; Gamarra, Javier G.P.; Liang, Jingjing; Crouzeilles, Renato; Hérault, Bruno; Aragão, Luiz E.O.C.; Silva, Carlos Alberto; Almeyda-Zambrano, Angelica M. title: Emerging threats linking tropical deforestation and the COVID-19 pandemic date: 2020-09-30 journal: Perspect Ecol Conserv DOI: 10.1016/j.pecon.2020.09.006 sha: doc_id: 290766 cord_uid: aoyvdyra Tropical deforestation drivers are complex and can change rapidly in periods of profound societal transformation, such as those during a pandemic. We present a conceptual framework linking tropical deforestation and the current pandemic.
    keywords: countries; covid-19; deforestation; health; pandemic
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        item: #3086 of 7819
          id: cord-290771-18dj37dj
      author: Tzeng, Ching-Wei D.
       title: Cancer Surgery Scheduling During and After the COVID-19 First Wave: The MD Anderson Cancer Center Experience
        date: 2020-05-18
       words: 4872
      flesch: 33
     summary: Head and neck surgical oncology in the time of a pandemic: Subsite-specific triage guidelines during the COVID-19 pandemic Changing practice patterns in head & neck oncologic surgery in the early COVID-19 era Safety recommendations for evaluation and surgery of the head and neck during the COVID-19 pandemic Thoracic Surgery Outcomes Research Network Inc. COVID-19 guidance for triage of operations for thoracic malignancies: a consensus statement from thoracic surgery outcomes research network Management of cancer surgery cases during the COVID-19 pandemic: considerations COVID-19: Elective Case Triage Guidelines for Surgical Care Approaching surgical triage during the COVID-19 pandemic Surgical decision-making and prioritization for cancer patients at the onset of the COVID-19 pandemic: a multidisciplinary approach Neoadjuvant chemotherapy or primary surgery in stage IIIC or IV ovarian cancer Survival implications of time to surgical treatment of endometrial cancers Urology practice during COVID-19 pandemic COVID-19 Resources: Disease-Site Specific Management Resources Recommendations for prioritization, treatment, and triage of breast cancer patients during the COVID-19 pandemic. Based on early case reports, cancer patients with COVID-19 used greater hospital resources including ICU beds with higher mortality rates than the general population.
    keywords: april; cancer; care; case; chemotherapy; covid-19; disease; hospital; operations; patients; review; risk; surgery
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        item: #3087 of 7819
          id: cord-290814-j3sp3dq9
      author: Song, Jehun
       title: Coronavirus Disease 19 (COVID-19) complicated with pneumonia in a patient with rheumatoid arthritis receiving conventional disease-modifying antirheumatic drugs
        date: 2020-04-20
       words: 1923
      flesch: 39
     summary: For patients admitted to hospitals with severe infections, temporary discontinuation of most DMARDs is recommended to allow RA patients to develop protective immunity and eliminate the pathogens [10] . After the discontinuation of cDMARDs (except hydroxychloroquine) and with the administration of antiviral agents, COVID-19 pneumonia was improved, providing a reference case for the management of such patients.
    keywords: covid-19; disease; patients; pneumonia; treatment
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        item: #3088 of 7819
          id: cord-290815-08rafcek
      author: McMaster, David
       title: COVID‐19: opportunities for professional development and disruptive innovation
        date: 2020-05-28
       words: 896
      flesch: 25
     summary: key: cord-290815-08rafcek authors: McMaster, David; Veremu, Munashe; Santucci, Catherine title: COVID‐19: opportunities for professional development and disruptive innovation date: 2020-05-28 journal: Clin Teach DOI: 10.1111/tct.13175 sha: doc_id: 290815 cord_uid: 08rafcek nan A s a group of medical students from the United Kingdom (UK), we currently find ourselves in a period of uncertainty as the continuing coronavirus disease 2019 (COVID-19) pandemic has caused widespread disruption to medical education. In addition, innovation driven by medical students during this viral pandemic may accelerate the continuing transformation away from traditional teaching methods in medical education.
    keywords: covid-19; education; students
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        item: #3089 of 7819
          id: cord-290820-28ggcjx0
      author: Lim, Michael Anthonius
       title: Sports activities during any pandemic lockdown
        date: 2020-07-04
       words: 2311
      flesch: 34
     summary: To help delay and mitigate COVID-19 spread, staying at home is still encouraged and the Centers for Disease Control and Prevention (CDC) recommends daily physical activity for both children (60 min/day) and adults (30 min/day). Zone7, an artificial intelligence platform specialized in predicting injury risk, conducted research in the English Premier League, which suggested an increase in injury incidence by 25% due to a congested schedule (eight matches plus training in 30 days)
    keywords: athletes; covid-19; exercise; home; pandemic; risk; sports; training
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        item: #3090 of 7819
          id: cord-290832-zmj59rc3
      author: Recinella, Guerino
       title: Prognostic role of nutritional status in elderly patients hospitalized for COVID-19: a monocentric study
        date: 2020-10-08
       words: 2989
      flesch: 41
     summary: We, therefore, believe that maximum attention should be paid to COVID-19 elderly patient with malnutrition and where possible start quickly a supplementary feeding. The association of GNRI with a respiratory parameter (PaO2/FiO2) provides a comprehensive prognostic tool for predicting adverse outcomes in elderly COVID-19 patients.
    keywords: covid-19; gnri; hospital; patients; risk; status; study
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        item: #3091 of 7819
          id: cord-290836-jldfrec9
      author: Laosa, Olga
       title: Rapid assessment at hospital admission of mortality risk from COVID-19: the role of functional status
        date: 2020-10-08
       words: 1862
      flesch: 50
     summary: The role of functional status in determining poor outcomes in old patients with COVID- 46 19 has not been yet firmly established. key: cord-290836-jldfrec9 authors: Laosa, Olga; Pedraza, Laura; Álvarez-Bustos, Alejandro; Carnicero, Jose A.; Rodriguez-Artalejo, Fernando; Rodriguez-Mañas, Leocadio title: Rapid assessment at hospital admission of mortality risk from COVID-19: the role of functional status date: 2020-10-08 journal: J Am Med Dir Assoc DOI: 10.1016/j.jamda.2020.10.002 sha: doc_id: 290836 cord_uid: jldfrec9 Objective To evaluate the role of functional status along with other used clinical factors on the occurrence of death in patients hospitalized with COVID-19.
    keywords: covid-19; mortality; patients; risk; study
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        item: #3092 of 7819
          id: cord-290841-lo84h1yf
      author: Lim, Rodrick
       title: Emergency physician mental health during the subacute phase of the COVID-19 pandemic
        date: 2020-07-03
       words: 421
      flesch: 30
     summary: key: cord-290841-lo84h1yf authors: Lim, Rodrick; Ali, Huma; Gagnier, Rachel; Marlborough, Michelle; Northcott, Sandra title: Emergency physician mental health during the subacute phase of the COVID-19 pandemic date: 2020-07-03 journal: CJEM DOI: 10.1017/cem.2020.442 sha: doc_id: 290841 cord_uid: lo84h1yf nan The coronavirus disease (COVID-19) pandemic presents unique mental stressors for emergency physicians (EPs). We propose that three important themes during the subacute phase are important to identify to support EP mental health: uncertainty, lack of control, and discord.
    keywords: eps; health
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        item: #3093 of 7819
          id: cord-290856-6de0mwg0
      author: Abbo, Aharon (Ronnie)
       title: Technological Developments and Strategic Management for Overcoming the COVID-19 Challenge within the Hospital Setting in Israel
        date: 2020-07-31
       words: 4154
      flesch: 33
     summary: The system is currently being investigated in COVID-19 patients as a tool that could potentially assist in following up the respiratory status of the COVID-19 patients and assist in managing those who require mechanical ventilation. The use of existing ultrasound systems (point-of-care ultrasound [POCUS], handheld) to assess patient pulmonary status and diagnose lung pathologies has been reported in COVID-19 patients.
    keywords: care; control; covid-19; disease; health; hospital; medical; monitoring; patients; system; teams; temperature
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        item: #3094 of 7819
          id: cord-290863-f0wpsaip
      author: Tenforde, Mark W.
       title: Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health Care Systems Network — United States, March–June 2020
        date: 2020-07-31
       words: 2976
      flesch: 43
     summary: Whereas previous studies have found race/ethnicity to be a risk factor for severe COVID-19 illness (10) , this study of patients whose illness was diagnosed in an outpatient setting did not find an association between race/ethnicity and return to usual health although the modest number of respondents might have limited our ability to detect associations. Generalized estimating equation regression models with exchangeable correlation structure accounting for clustering by site were fitted to evaluate the association between baseline characteristics and return to usual health, adjusting for potential a priori-selected confounders.
    keywords: covid-19; date; days; health; respondents; symptoms; testing
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        item: #3095 of 7819
          id: cord-290895-tb0xald0
      author: Indu, Purushothaman
       title: Raltegravir, Indinavir, Tipranavir, Dolutegravir, and Etravirine against main protease and RNA-dependent RNA polymerase of SARS-CoV-2: A molecular docking and drug repurposing approach
        date: 2020-10-26
       words: 2638
      flesch: 47
     summary: In this study, 3D structures of FDA approved small molecule antiviral drugs were retrieved from PubChem and unavailable 3D structures for antiviral drugs were developed using the chemical tool box Open Babel Drug repurposing strategy helps to find out the drugs for COVID-19 treatment from existing FDA approved antiviral drugs.
    keywords: covid-19; drugs; fda; indinavir; rdrp; sars; study
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        item: #3096 of 7819
          id: cord-290921-dozqofrm
      author: Tan, Limin
       title: Choice behavior of commuters' rail transit mode during the COVID-19 pandemic based on logistic model
        date: 2020-09-19
       words: 750
      flesch: 41
     summary: The results show that: occupation, commuting tools before the COVID-19 pandemic, walking time from residence to the nearest subway station, the possibility of being infected in private car and the possibility of being infected in public transport have significant influence on the commuters’ choice of rail transit. Commuters who think that the risk of being infected with the virus in public transport is higher have a lower probability of choosing rail transit.
    keywords: covid-19; transit
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        item: #3097 of 7819
          id: cord-290938-v7giuq53
      author: Ochoa-Callejero, L.
       title: Circulating levels of calcitonin gene-related peptide (CGRP) are lower in COVID-19 patients
        date: 2020-10-02
       words: 3190
      flesch: 40
     summary: Results: CGRP levels greatly decreased in COVID-19 patients (p<0.001) when compared to controls, and there were no significant differences due to disease severity, sex, age, or comorbidities. In this study we have shown that CGRP serum levels become significantly reduced in COVID-19 patients, independently of their disease severity status.
    keywords: cgrp; covid-19; license; medrxiv; october; patients; preprint
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        item: #3098 of 7819
          id: cord-290939-tqi0v1w8
      author: Boon, Ian S.
       title: Effect of COVID-19 pandemic on cancer clinician decision making: Known knowns and known unknowns
        date: 2020-04-25
       words: 489
      flesch: 41
     summary: key: cord-290939-tqi0v1w8 authors: Boon, Ian S.; Au Yong, Tracy P.T.; Boon, Cheng S. title: Effect of COVID-19 pandemic on cancer clinician decision making: Known knowns and known unknowns date: 2020-04-25 journal: Clin Oncol (R Coll Radiol) DOI: 10.1016/j.clon.2020.04.010 sha: doc_id: 290939 cord_uid: tqi0v1w8 nan Madam -COVID-19 is a global pandemic [1] and poses a significant challenge to cancer patients. Oncologist will have to recognise the uncertainty in quantifying the risks of COVID-19 to cancer patients.
    keywords: cancer; covid-19
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        item: #3099 of 7819
          id: cord-290947-5ewpvo4j
      author: Carda, Stefano
       title: The role of physical and rehabilitation medicine in the COVID-19 pandemic: the clinician's view
        date: 2020-04-18
       words: 1550
      flesch: 35
     summary: Cureus The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients A first Case of Meningitis/Encephalitis associated with SARS-Coronavirus-2 Two-year cognitive, emotional, and quality-of-life outcomes in acute respiratory distress syndrome Pulmonary function and exercise capacity in survivors of severe acute respiratory syndrome Recovery from Dysphagia Symptoms after Oral Endotracheal Intubation in Acute Respiratory Distress Syndrome Survivors. A 5-Year Longitudinal Study Clinical observation and management of COVID-19 patients.
    keywords: covid-19; patients; pmr; rehabilitation; sato2
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        item: #3100 of 7819
          id: cord-290950-v28kilvn
      author: Peyrony, Olivier
       title: Surfaces and equipment contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in the Emergency Department at a university hospital
        date: 2020-08-07
       words: 3160
      flesch: 51
     summary: This high positivity rate may be explained by the highest proportion of samples that were made in patient care areas, medical equipment and PPE just after COVID-19 patient care. In patient care areas, 5/46 (10.9%) of the surfaces directly in contact with COVID-19 patients revealed the presence of SARS-CoV-2 RNA, and 4/56 (7.1%) of the surfaces that were not directly in contact with COVID-19 patients were positive.
    keywords: care; cov-2; covid-19; patient; rooms; sars; surfaces
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        item: #3101 of 7819
          id: cord-290952-tbsccwgx
      author: Ullah, Saif
       title: Modeling the impact of non-pharmaceutical interventions on the dynamics of novel coronavirus with optimal control analysis with a case study
        date: 2020-07-03
       words: 6466
      flesch: 47
     summary: The simulation results of without optimal control model are shown in section 5. Therefore, the largest compact invariant set in ∆ is the singleton set W 0 and using the LaSalle's invariant principle [17] , W 0 is globally asymptotically stable in ∆. The present section investigates the data fitting using model (3) to the confirmed reported COVID-19 infected cases in Pakistan.
    keywords: cases; control; covid-19; covid-19 model; disease; individuals; model; optimal; pakistan
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        item: #3102 of 7819
          id: cord-290955-m2igkcxv
      author: Asli, Rosmonaliza
       title: Case Report: Right Bundle Brunch Block and QTc Prolongation in a Patient with Novel Coronavirus Disease (COVID-19) Treated with Hydroxychloroquine
        date: 2020-05-07
       words: 1391
      flesch: 45
     summary: Therefore, clinicians should exercise caution and assess cardiac risk if considering HCQ treatment for COVID-19. This case highlights a significant and potentially life-threatening complication of HCQ use.
    keywords: covid-19; day; hcq; qtc
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        item: #3103 of 7819
          id: cord-290960-0kdv91j0
      author: Rojas-Marte, G
       title: Outcomes in patients with severe COVID-19 disease treated with tocilizumab: a case–controlled study
        date: 2020-06-19
       words: 2778
      flesch: 48
     summary: Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City Area Effective treatment of severe COVID-19 patients with tocilizumab Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)? Tocilizumab for treatment of severe COVID-19 patients: preliminary results from SMAtteo COvid19 REgistry (SMACORE) Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis Prediction of infection risk in rheumatoid arthritis patients treated with biologics: are we any closer to risk stratification?
    keywords: covid-19; disease; group; patients; tocilizumab; treatment
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        item: #3104 of 7819
          id: cord-290975-2kmvyovm
      author: Martinotti, Giovanni
       title: Psychopathological Burden and Quality of Life in Substance Users During the COVID-19 Lockdown Period in Italy
        date: 2020-09-03
       words: 4251
      flesch: 34
     summary: Minerva Cardioangiol COVID-19 outbreak: Challenges for Addiction services in India Mitigating and learning from the impact of COVID-19 infection on addictive disorders Editorial: Challenges to Opioid Use Disorders During COVID-19 Opioid use disorder and the COVID 19 pandemic: A call to sustain regulatory easements and further expand access to treatment A clinical scale for the self-assessment of irritability A Rating Instrument For Anxiety Disorders Assessment of a new self-rating scale for post-traumatic stress disorder Manual for Beck Depression Inventory-II Validation of a substance craving questionnaire (SCQ) in Italian population The psychological impact of quarantine and how to reduce it: rapid review of the evidence Epidemic of COVID-19 in China and associated Psychological Problems Comparison of Prevalence and Associated Factors of Anxiety and Depression among People Affected by versus People Unaffected by Quarantine during the COVID-19 Epidemic in Southwestern China Mental Health, Risk Factors, and Social Media Use During the COVID-19 Epidemic and Cordon Sanitaire Among the Community and Health Professionals in Wuhan, China: Cross-Sectional Survey A longitudinal study on the mental health of general population during the COVID-19 epidemic in China A nationwide survey of psychological distress among italian people during the covid-19 pandemic: Immediate psychological responses and associated factors Mental health consequences during the initial stage of the 2020 Coronavirus pandemic (COVID-19) in Spain Transcranial Direct Current Stimulation Reduces Craving in Substance Use Disorders: A Double-blind, Placebo-Controlled Study Alcohol urges in alcohol-dependent drinkers: Further validation of the Alcohol Urge Questionnaire in an untreated community clinical population Craving and Other Transdiagnostic Dimensions in Addiction: Toward Personalized Neuromodulation Treatments Psychological stress, drug-related cues and cocaine craving Ecological momentary assessment of the effects of craving and affect on risk for relapse during substance abuse treatment Breaking good: Breaking ties with social groups may be good for recovery from substance misuse Medicines and risk/benefit decisions Association between alcohol craving and health-related quality of life among veterans with cooccurring conditions Effects of Exercise on Depression, Anxiety, Cognitive Control, Craving, Physical Fitness and Quality of Life in Methamphetamine-Dependent Patients Stress, craving and mood as predictors of early dropout from opioid agonist therapy Effects of anxiety and mood disorders on craving and substance use among patients with substance use disorder: An ecological momentary assessment study The association between depression and craving in alcohol dependency is moderated by gender and by alexithymia factors Telepsychiatry and other cutting edge technologies in Covid-19 pandemic: bridging the distance in mental health assistance Such a notion is relevant because substance craving is a known predictor of relapse after treatment for SUDs (36) .
    keywords: anxiety; covid-19; craving; health; life; pandemic; patients; study; substance; symptoms
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        item: #3105 of 7819
          id: cord-290987-644d1i1n
      author: Mostafa, Mohamed K.
       title: The impact of COVID 19 on air pollution levels and other environmental indicators - A case study of Egypt
        date: 2020-10-10
       words: 6523
      flesch: 38
     summary: NO x at an urban and a suburban site in Nanjing A dynamic analysis of air pollution emissions in China: key: cord-290987-644d1i1n authors: Mostafa, Mohamed K.; Gamal, Gamil; Wafiq, A. title: The impact of COVID 19 on air pollution levels and other environmental indicators - A case study of Egypt date: 2020-10-10 journal: J Environ Manage DOI: 10.1016/j.jenvman.2020.111496 sha: doc_id: 290987 cord_uid: 644d1i1n
    keywords: air; consumption; covid-19; egypt; emissions; environment; health; levels; lockdown; ozone; pandemic; pollution; quality; reduction; waste
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        item: #3106 of 7819
          id: cord-290995-ok6lsh9m
      author: Zhou, Xiang
       title: COVID-19 infection in patients with multiple myeloma: a German-Chinese experience from Würzburg and Wuhan
        date: 2020-07-18
       words: 1303
      flesch: 45
     summary: Dufour et al. recently reported the experience from Belgium in this Journal (published on 23 June 2020), which also demonstrated a high mortality of 35% caused by COVID-19 infection in MM patients, and patients with immigration background especially North-Africans showed the worst survival outcome. Therefore, we conducted this study of MM patients infected by COVID-19 and compared the clinical features of patients from Germany and China.
    keywords: covid-19; nos; patients
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        item: #3107 of 7819
          id: cord-291016-c83fs5ih
      author: Gori, Tommaso
       title: Perspective: cardiovascular disease and the Covid-19 pandemic
        date: 2020-04-10
       words: 1624
      flesch: 36
     summary: Cardiovascular disease patients are at particularly high risk for mortality from Covid-19 due to their frailty and susceptibility for a myocardial involvement [1] . In addition, drugs used to treat Covid-19 patients have cardiovascular side effects (Table 1) , the burden of which will unfortunately need to be evaluated in retrospect.
    keywords: covid-19; disease; patients; risk; sars
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        item: #3108 of 7819
          id: cord-291018-5j4nt2qs
      author: Foddai, Alessandro
       title: Surveillance to improve evidence for community control decisions during the COVID-19 pandemic – Opening the animal epidemic toolbox for public health
        date: 2020-03-27
       words: 972
      flesch: 40
     summary: As veterinary epidemiologists, we applaud the work that is currently being done by public health systems all around the world. Health systems all over the world are trying to control the outbreak in the shortest possible time.
    keywords: control; health; surveillance
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        item: #3109 of 7819
          id: cord-291023-vltxefr7
      author: Murt, Ahmet
       title: Convalescent COVID-19 Patients on Hemodialysis: When Should We End Isolation?
        date: 2020-05-19
       words: 500
      flesch: 47
     summary: Suspected and confirmed COVID-19 patients should ideally be dialysed in a separate isolation room [1] . As understanding of the disease evolves, we have more patients for whom a discharge is planned, and none of the guides has mentioned about the ideal timing to end the isolation for hemodialysis patients yet.
    keywords: covid-19; patients
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        item: #3110 of 7819
          id: cord-291025-u5z8zji3
      author: Karami, Parisa
       title: Mortality of a pregnant patient diagnosed with COVID-19: A case report with clinical, radiological, and histopathological findings
        date: 2020-04-11
       words: 2883
      flesch: 45
     summary: According to the released data to that date and considering the imaging findings on COVID-19 patients, results belonging to this patient were nonspecific for early stages of COVID -19 pneumonia. So far, few reports have provided information on the clinical and imaging follow up of pregnant patients with COVID-19.
    keywords: coronavirus; covid-19; disease; findings; patient
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        item: #3111 of 7819
          id: cord-291032-l813q689
      author: Shupler, M.
       title: COVID-19 Lockdown in a Kenyan Informal Settlement: Impacts on Household Energy and Food Security
        date: 2020-05-29
       words: 4673
      flesch: 48
     summary: The high cost of LPG refills (85% of LPG households used 6 kg cylinders) explains the appeal of small incremental payments via PAYG smart-meter technology among participants (Table 2 ). key: cord-291032-l813q689 authors: Shupler, M.; Mwitari, J.; Gohole, A.; Anderson de Cuevas, R.; Puzzolo, E.; Cukic, I.; Nix, E.; Pope, D. title: COVID-19 Lockdown in a Kenyan Informal Settlement: Impacts on Household Energy and Food Security date: 2020-05-29 journal: nan DOI: 10.1101/2020.05.27.20115113 sha: doc_id: 291032 cord_uid: l813q689 A COVID-19 lockdown may impact household fuel use and food security for ~700 million sub-Saharan Africans who rely on polluting fuels (e.g. wood, kerosene) for household energy and typically work in the informal economy.
    keywords: cooking; covid-19; fuel; health; households; kerosene; license; lockdown; lpg; preprint; table
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        item: #3112 of 7819
          id: cord-291037-19csqq89
      author: Janssen, Rob
       title: Vitamin K epoxide reductase complex subunit 1 (VKORC1) gene polymorphism as determinant of differences in Covid-19-related disease severity
        date: 2020-08-25
       words: 2205
      flesch: 33
     summary: key: cord-291037-19csqq89 authors: Janssen, Rob; Walk, Jona title: Vitamin K epoxide reductase complex subunit 1 (VKORC1) gene polymorphism as determinant of differences in Covid-19-related disease severity date: 2020-08-25 journal: Med Hypotheses DOI: 10.1016/j.mehy.2020.110218 sha: doc_id: 291037 cord_uid: 19csqq89 Covid-19, caused by SARS-CoV-2, has major world-wide health-related and socio-economic consequences. Activation of procoagulant factor II by vitamin K in the liver, however, was hardly affected and not different between Covid-19 patients with good and poor outcomes
    keywords: allele; covid-19; vitamin; vkorc1
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        item: #3113 of 7819
          id: cord-291038-n8bk541m
      author: Bhala, Neeraj
       title: Sharpening the global focus on ethnicity and race in the time of COVID-19
        date: 2020-05-10
       words: 1681
      flesch: 42
     summary: For comparison, the 2011 census shows that ethnic minority groups made up about 14% of the UK population. Additionally, National Health Service (NHS) health-care staff from ethnic minority groups seem to have died in disproportionate numbers from COVID-19, even when accounting for the high proportion of people from these groups who are employed in the NHS and work on the front line.
    keywords: covid-19; ethnic; groups; health
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        item: #3114 of 7819
          id: cord-291144-6p40cqvk
      author: Strom, Mark A.
       title: Reticular skin eruption as the initial sign of coronavirus disease 2019 infection
        date: 2020-06-24
       words: 1079
      flesch: 29
     summary: Clinical features of patients infected with 2019 novel coronavirus in Wuhan Coagulopathy and antiphospholipid antibodies in patients with Covid-19 Hypercoagulability of COVID-19 patients in intensive care unit. Reticular skin findings are increasingly described in patients with COVID-19, although they appear less frequently than other cutaneous manifestations.
    keywords: covid-19; eruption; patient
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        item: #3115 of 7819
          id: cord-291146-f3e5ynhu
      author: Sarangarajan, Rangaprasad
       title: Ethnic Prevalence of Angiotensin-Converting Enzyme Deletion (D) Polymorphism and COVID-19 Risk: Rationale for Use of Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers
        date: 2020-09-08
       words: 4330
      flesch: 25
     summary: The study objective was to describe a biological framework associating ethnic prevalence of ACE deletion polymorphism to COVID-19 comorbidities providing rationale for therapeutic utility of ACE-I/ARBs to improve outcomes. The figure describes the increased activation of ACE and generation of Ang-II as a consequence of COVID-19-mediated reduction in ACE2 in the presence of ACE deletion polymorphism.
    keywords: ace; ace2; angiotensin; converting; covid-19; deletion; disease; enzyme; polymorphism
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        item: #3116 of 7819
          id: cord-291150-u9v7gp37
      author: Zhang, Xiao
       title: Suggestions for safety and protection control in Department of Nuclear Medicine during the outbreak of COVID-19
        date: 2020-03-25
       words: 483
      flesch: 43
     summary: European Centre for Disease Prevention and Control Clinical features of patients infected with 2019 novel coronavirus in Wuhan 18 F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases Expert consensus on the safety prevention and control of nuclear medicine diagnosis and treatment during the outbreak of COVID-19 COVID-19): Interim Infection Prevention and Control Recommendations for Patients with Confirmed Coronavirus Disease 2019 (COVID-19) or Persons Under Investigation for COVID-19 in Healthcare Settings Patients with confirmed or suspected diagnosis of COVID-19 should be invited to postpone the radiopharmaceutical imaging and treatment.
    keywords: covid-19; patients
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        item: #3117 of 7819
          id: cord-291155-2fze1t92
      author: Hariyanto, Timotius Ivan
       title: Statin therapy did not improve the in-hospital outcome of coronavirus disease 2019 (COVID-19) infection
        date: 2020-08-26
       words: 1389
      flesch: 44
     summary: Moreover, pleiotropic properties of statin can exert antiinflammatory effects by inhibiting NLRP3 inflammasome through the TLR4/MyD88/NF-κB pathway, therefore restraining the uncontrolled inflammation which can be fatal in COVID-19 patients. The title, abstract, and full text of all articles identified that matched the search criteria were assessed, and those reporting the rate of metformin use in COVID-19 patients with a clinically validated definition of severe disease and mortality were included in this meta-analysis.
    keywords: covid-19; outcomes; patients; statin
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        item: #3118 of 7819
          id: cord-291168-4u4cssky
      author: Martin-Villares, Cristina
       title: Outcome of 1890 tracheostomies for critical COVID-19 patients: a national cohort study in Spain
        date: 2020-08-04
       words: 3223
      flesch: 46
     summary: To the best of our knowledge, this is the largest cohort of COVID-19 patients undergoing tracheostomy. In this pandemic scenario, with limited ICUs resources [10] , tracheostomy seems to help COVID-19 patients to get off the mechanical ventilation [11] , reducing the respiratory effort in patients with limited pulmonary reserves, shortening the dead space and enabling the suctioning of accumulated mucous.
    keywords: covid-19; data; hospital; pandemic; patients; tracheostomies; tracheostomy; ventilation; weaning
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        item: #3119 of 7819
          id: cord-291176-evb6yt0r
      author: Giorgi Rossi, Paolo
       title: Characteristics and outcomes of a cohort of COVID-19 patients in the Province of Reggio Emilia, Italy
        date: 2020-08-27
       words: 4569
      flesch: 42
     summary: key: cord-291176-evb6yt0r authors: Giorgi Rossi, Paolo; Marino, Massimiliano; Formisano, Debora; Venturelli, Francesco; Vicentini, Massimo; Grilli, Roberto title: Characteristics and outcomes of a cohort of COVID-19 patients in the Province of Reggio Emilia, Italy date: 2020-08-27 journal: PLoS One DOI: 10.1371/journal.pone.0238281 sha: doc_id: 291176 cord_uid: evb6yt0r This is a population-based prospective cohort study on archive data describing the age- and sex-specific prevalence of COVID-19 and its prognostic factors. The cohort of COVID-19 patients includes all symptomatic patients who tested positive with PCR between February 27 and April 2, 2020.
    keywords: age; covid-19; death; disease; hospitalization; patients; risk; study
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        item: #3120 of 7819
          id: cord-291184-uza4orb8
      author: Lyra, Wladimir
       title: COVID-19 pandemics modeling with SEIR(+CAQH), social distancing, and age stratification. The effect of vertical confinement and release in Brazil.
        date: 2020-04-14
       words: 3449
      flesch: 61
     summary: The effect of vertical confinement and release in Brazil. date: 2020-04-14 journal: nan DOI: 10.1101/2020.04.09.20060053 sha: doc_id: 291184 cord_uid: uza4orb8 The ongoing COVID-19 epidemics poses a particular challenge to low and middle income countries, making some of them consider the strategy of vertical confinement.
    keywords: age; confinement; license; model; number; population; preprint
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        item: #3121 of 7819
          id: cord-291187-8mbvmw0u
      author: Fuentes-García, Juan Pedro
       title: The Effect of COVID-19 Confinement in Behavioral, Psychological, and Training Patterns of Chess Players
        date: 2020-09-11
       words: 4017
      flesch: 41
     summary: The benefits of chess for the intellectual and social-emotional enrichment in schoolchildren Sport-specific diet contribution to mental hygiene of chess player Dealing with sleep problems during home confinement due to the COVID-19 outbreak: practical recommendations from a task force of the European CBT-I Academy A longitudinal study of prisoners on remand: psychiatric prevalence, incidence and psychopathology in solitary vs. nonsolitary confinement Personality and leisure activities -an illustration with chess players Psychophysiological stress response of a paralympic athlete during an ultraendurance event. These characteristics could provide chess players a certain advantage in facing quarantine situations.
    keywords: chess; confinement; covid-19; effect; level; players; study
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        item: #3122 of 7819
          id: cord-291188-ddw6ir08
      author: Kip, K. E.
       title: Temporal Changes in Clinical Practice with COVID-19 Hospitalized Patients: Potential Explanations for Better In-Hospital Outcomes
        date: 2020-09-29
       words: 3466
      flesch: 36
     summary: Because some facilities used intensive care units for the care of COVID-19 patients regardless of illness acuity, we did not use intensive care unit admission as an outcome. The infection fatality rate says 'no' First Opinion COVID-Net: A weekly summary of US COVID-19 hospitalization data Respiratory support in COVID-19 patients, with a focus on resource-limited settings Effects of temperature variation and humidity on the death of COVID-19 in Wuhan Second coronavirus strain may be more infectiousbut some scientists are skeptical Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus Testing strategy for coronavirus (COVID-19) in high-density critical infrastructure workplaces after a COVID-19 case is identified Universal and serial laboratory testing for SARS-CoV-2 at a long-term care skilled nursing facility for veterans July brings major changes for coronavirus testing and tracing of college athletes
    keywords: covid-19; epoch; hospital; license; medrxiv; patients; preprint
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        item: #3123 of 7819
          id: cord-291190-f6km3c7z
      author: Nasi, Aikaterini
       title: Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention
        date: 2020-06-18
       words: 3004
      flesch: 32
     summary: Hereby, based on literature review from the current pandemic and previous outbreaks with corona viruses we analyze the impact of the virus infection on cell stress responses and redox balance. Hereby, based on literature review from the current pandemic and previous outbreaks with corona viruses we analyze the impact of the virus infection on cell stress responses and redox balance.
    keywords: cell; covid-19; infection; production; responses; ros; sars; stress
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        item: #3124 of 7819
          id: cord-291226-xdq2edy0
      author: Stefely, Jonathan A.
       title: Marked factor V activity elevation in severe COVID‐19 is associated with venous thromboembolism
        date: 2020-08-24
       words: 5594
      flesch: 42
     summary: In summary, factor V activity was significantly higher in severe COVID-19 patients than in contemporaneous controls as well as historical controls, and high factor V activity was associated with thromboembolic complications of COVID-19. Factor V activity was significantly elevated in COVID‐19 (median 150 IU/dL, range 34–248 IU/dL) compared to contemporaneous controls (median 105 IU/dL, range 22–161 IU/dL) (P < 0.00001)—the strongest association with COVID‐19 of any parameter studied, including factor VIII, fibrinogen, and D‐dimer.
    keywords: activity; cases; covid-19; factor; factor v; patients
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        item: #3125 of 7819
          id: cord-291227-dgjieg7t
      author: Mandal, Manotosh
       title: A model based study on the dynamics of COVID-19: Prediction and control
        date: 2020-05-13
       words: 3255
      flesch: 55
     summary: The mathematical model can help when these intervention measures are the best strategies for disease control as well as how they might affect the disease dynamics. Further, we perform the sensitivity analysis of the essential reproduction number and found that reducing the contact of exposed and susceptible humans is the most critical factor in achieving disease control.
    keywords: analysis; control; covid-19; disease; model; optimal; system
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        item: #3126 of 7819
          id: cord-291234-rozpps6v
      author: Faye, C.
       title: A DISSYMMETRY IN THE FIGURES RELATED TO THE COVID-19 PANDEMIC IN THE WORLD: WHAT FACTORS EXPLAIN THE DIFFERENCE BETWEEN AFRICA AND THE REST OF THE WORLD?
        date: 2020-05-22
       words: 6829
      flesch: 50
     summary: The objective of this study is to relate the situation of Covid-19 in African countries with those of the countries most affected by the pandemic. The objective of this study is to relate the situation of Covid-19 in African countries with those of the countries most affected by the pandemic.
    keywords: cases; copyright; countries; covid-19; deaths; number; pandemic; population; preprint; variables; world
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        item: #3127 of 7819
          id: cord-291244-o4isx15k
      author: Ikuyama, Yuichi
       title: Successful recovery from critical COVID-19 pneumonia with extracorporeal membrane oxygenation: A case report
        date: 2020-05-31
       words: 2390
      flesch: 41
     summary: China Novel Coronavirus Investigating and Research Team, A Novel Coronavirus from Patients with Pneumonia in China China Medical Treatment Expert Group for Covid-19, Clinical Characteristics of Coronavirus Disease 2019 in China Clinical features of patients infected with 2019 novel coronavirus in Characteristics of and Important Lessons From the Coronavirus 19 COVID-19) Outbreak in China: So far, there are few reports on critical patients with COVID-19 [2, [5] [6] [7] .
    keywords: clinical; coronavirus; covid-19; ecmo; patient; pneumonia; treatment
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        item: #3128 of 7819
          id: cord-291253-5mzcvfm4
      author: Afzal, Waseem
       title: What we can learn from information flows about COVID‐19: Implications for research and practice
        date: 2020-10-22
       words: 3244
      flesch: 36
     summary: Moreover, COVID-19 information flows present a distinctive pattern in terms of the amplification of frequency and magnitude of information dissemination. The analysis revealed that that there are significant information imperfections in COVID-19 information flows, including the preponderance of incomplete information, misinformation, and disinformation, and the absence of information about some key turning points.
    keywords: china; covid-19; crisis; flows; information; news; virus
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        item: #3129 of 7819
          id: cord-291265-qmylxndp
      author: Moravvej, Zahra
       title: COVID-19 pandemic: Ophthalmic practice and precautions in a tertiary eye hospital in Iran
        date: 2020-04-23
       words: 1223
      flesch: 46
     summary: 4 Cases of conjunctivitis have been reported in COVID-19 patients. Medical specialties involve various examinations that may put patients and practitioners at risk of infection.
    keywords: covid-19; eye; hospital; infection; patients
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        item: #3130 of 7819
          id: cord-291271-movbn4dn
      author: Jahangiry, Leila
       title: Risk perception related to COVID-19 among the Iranian general population: an application of the extended parallel process model
        date: 2020-10-19
       words: 3338
      flesch: 49
     summary: Perceived risk scores showed that participants with confirmed coronavirus cases had significantly higher scores except for the perceived susceptibility scores. This indicated that more than half of participants had high perceived efficacy (i.e., self-efficacy and response efficacy).
    keywords: control; covid-19; efficacy; participants; risk; study
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        item: #3131 of 7819
          id: cord-291275-qylkm2tn
      author: Khosravi, Mohsen
       title: The challenges ahead for patients with feeding and eating disorders during the COVID-19 pandemic
        date: 2020-09-07
       words: 1415
      flesch: 38
     summary: Availability of data and materials N/a Ethics approval and consent to participate N/a Consent for publication N/a Mental health and the COVID-19 pandemic Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (COVID-19) epidemic among the general population in China COVID-19 and mental health: a review of the existing literature Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed Relationship of household food insecurity to health-related quality of life in a large sample of rural and urban women Food insecurity and bulimia nervosa in the United States Household food insecurity is associated with binge-eating disorder and obesity Food insecurity and eating disorder pathology Access to evidence-based care for eating disorders during the COVID-19 crisis Stressful life events and disordered eating behaviors: findings from project EAT Letter to the editor: headline stress disorder caused by Netnews during the outbreak of COVID-19 The psychological impact of quarantine and how to reduce it: rapid review of the evidence Are individuals with loss-of-control eating more prone to dietary lapse in behavioural weight loss treatment? An ecological momentary assessment study Binge abstinence is associated with reduced energy intake after treatment in patients with binge eating disorder and obesity COVID-19 and implications for eating disorders Eating disorders in the time of COVID-19 COVID-19 related misinformation on social media: a qualitative study from Iran Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations The author read and approved the final manuscript.
    keywords: covid-19; eating; food; health
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        item: #3132 of 7819
          id: cord-291311-5hw307v1
      author: Xiao, Hongjun
       title: How to avoid nosocomial spread during tracheostomy for COVID‐19 patients
        date: 2020-04-27
       words: 688
      flesch: 43
     summary: First, all procedures should be performed under general anesthesia, with deprivation of spontaneous respiration and application of muscle relaxants ( Figure 1A) , regardless of whether procedures of tracheostomy step by step for COVID-19 patients. How to avoid nosocomial spread during tracheostomy for COVID-19 patients To the editor, As the novel coronavirus (COVID-19) globally spreads, the COVID-19 pandemic is straining health-care workers worldwide.
    keywords: patients; tracheostomy
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        item: #3133 of 7819
          id: cord-291315-y40s45iv
      author: Logunov, Denis Y
       title: Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia
        date: 2020-09-04
       words: 5736
      flesch: 45
     summary: Thus, the presence of a pre-existing immune response to the components of vaccine vectors rAd26 and rAd5 does not affect the titre of RBD-specific antibodies in the serum of participants. [30] The incidence of adverse events in our studies was slightly lower than in other work; a comparative clinical study with other vaccines is needed to confirm these findings.
    keywords: cov-2; covid-19; days; participants; phase; rad26; rad5; sars; study; vaccination; vaccine; volunteers
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        item: #3134 of 7819
          id: cord-291366-d5d9l0xr
      author: Eirale, Cristiano
       title: Medical recommendations for home-confined footballers’ training during the COVID-19 pandemic: from evidence to practical application
        date: 2020-04-10
       words: 3187
      flesch: 41
     summary: In the absence of suitable equipment, strength training can be carried out at home with elastic resistance [45] or body weight exercises, for example pull-ups, push-ups, sit-ups, dips, Nordic hamstring exercise, etc [46, 47] . In any case, we do not recommend strength training to be carried out at maximal levels as there is evidence of a reduction of up to 15% of isometric strength in infected subjects who do not fully recover until a month after the illness [52] .
    keywords: activity; covid-19; evidence; exercise; period; strength; system; training
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        item: #3135 of 7819
          id: cord-291371-9wadja0w
      author: Zimmerman, R. K.
       title: Proposed Clinical Indicators for Efficient Screening and Testing for COVID-19 Infection from Classification and Regression Trees (CART) Analysis
        date: 2020-05-14
       words: 1449
      flesch: 57
     summary: https://doi.org/10.1101/2020.05.11.20097980 doi: medRxiv preprint or loss of taste or smell and contact with COVID-19 case --were included in the CART model as categorical predictors. If COVID-19 case exposure did not occur, and the patient reported neither loss of taste or smell nor nausea or vomiting the patient need not be tested.
    keywords: covid-19; preprint; testing
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        item: #3136 of 7819
          id: cord-291387-04inonzh
      author: Deering, Thomas F.
       title: COllaboration is a Valuable International/Interdisciplinary Directive for Electrophysiology Progress: NOvel & Tangible Important Lessons Learned COVID-EP: NOT ILL Digital health lessons learned from the COVID experience can improve arrhythmic outcomes
        date: 2020-08-31
       words: 2576
      flesch: 28
     summary: Modification of digital COVID-19 surveillance approaches and their application to arrhythmic health care problems, such as sudden cardiac arrest, might allow us to identify high-risk populations in need of better or alternative preventive and therapeutic approaches. If we hope to apply successfully the lessons that we can learn from the application of digital health innovations during the COVID-19 crisis and realize the goal of generating a foundation on which we can accelerate progress in eradicating arrhythmic suffering and death, several steps are mandatory.
    keywords: approaches; arrhythmia; care; covid-19; health; pandemic; patients
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        item: #3137 of 7819
          id: cord-291393-iht5zndl
      author: De Angelis, Giulia
       title: Confirmed or unconfirmed cases of 2019 novel coronavirus pneumonia in Italian patients: a retrospective analysis of clinical features
        date: 2020-10-19
       words: 2722
      flesch: 42
     summary: Additionally, the proportion of ARDS in the group of COVID-19 confirmed patients was significantly higher than in the group of COVID-19 unconfirmed patients. We tested the hypothesis that negative patients did not differ from SARS-CoV-2 RNA positive patients by comparing features of 165 cases with clinically diagnosed 2019-nCoV pneumonia in our hospital.
    keywords: cases; covid-19; ncov; patients; pneumonia; respiratory; sars
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        item: #3138 of 7819
          id: cord-291397-look6ddt
      author: Roberto, Palumbo
       title: Current treatment of COVID-19 in renal patients: hope or hype?
        date: 2020-09-28
       words: 5842
      flesch: 41
     summary: Chloroquine is a potent inhibitor of SARS coronavirus infection and spread State Administration of Traditional Chinese Medicine (Trial Version 7) Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro RETRACTED: Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis Effect of high vs low doses of chloroquine diphosphate as adjunctive therapy for patients hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: a randomized clinical trial Zika virus cell tropism in the developing human brain and inhibition by azithromycin Evaluation of Ebola virus inhibitors for drug repurposing Saudi critical care trials group, macrolides in critically ill patients with middle east respiratory syndrome Azithromycin for hospitalized patients with suspected or confirmed COVID-19, HAHPS (NCT04329832) Latest version Azithromycin for COVID-19 Treatment in Outpatients Nationwide, ACTION (NCT04332107) Latest version Surviving sepsis campaign: guidelines on the management of critically Ill adults with coronavirus disease 2019 (COVID-19) key: cord-291397-look6ddt authors: Roberto, Palumbo; Francesco, Londrino; Emanuela, Cordova; Giorgia, Gambardella; Pasquale, Niscola; Sara, Dominijanni title: Current treatment of COVID-19 in renal patients: hope or hype? date: 2020-09-28 journal: Intern Emerg Med DOI: 10.1007/s11739-020-02510-0 sha: doc_id:
    keywords: clinical; coronavirus; cov-2; covid-19; disease; dose; infection; patients; pneumonia; renal; sars; treatment; use
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        item: #3139 of 7819
          id: cord-291410-umaxozwk
      author: Gupta, Vishal
       title: COVID-19 and Acute Pancreatitis: What Do Surgeons Need to Know?
        date: 2020-06-05
       words: 1657
      flesch: 36
     summary: It is important to make the correct diagnosis of AP in COVID-19 patients although it can be difficult. Rather, criteria as per the revised Atlanta classification should be used to make the correct diagnosis which requires at least two of the following three criteria: (1) typical abdominal pain, (2) serum amylase or lipase > 3 times the upper normal limit, and (3) characteristic findings on diagnostic imaging; the latter might play more significant role in COVID-19 patients where clinical evaluation for abdominal symptoms might not be feasible in severe case requiring intensive care unit care with ventilatory support.
    keywords: covid-19; pancreatitis; patients
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        item: #3140 of 7819
          id: cord-291413-cgec7150
      author: Al-Jehani, Hosam
       title: MENA-SINO Consensus Statement on Implementing Care Pathways for Acute Neurovascular Emergencies During the COVID-19 Pandemic
        date: 2020-08-25
       words: 3767
      flesch: 44
     summary: Published and anecdotal reports suggest that during the pandemic, there has been a drastic reduction in the number of stroke patients being evaluated in the emergency room (ER) or being admitted to hospitals worldwide (6) . In theory, monitored anesthesia care (MAC) may prevent intense aerosolization; however, stroke patients undergoing MAC sedation may require supplemental oxygen via a nasal cannula mask or other methods, such as chin-lift or jaw thrust maneuvers, to improve oxygenation, which may increase the degree of airborne exposure to the anesthesia provider and other involved HCWs.
    keywords: care; challenges; covid-19; medical; pandemic; patients; stroke
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        item: #3141 of 7819
          id: cord-291414-kyi8tfqd
      author: Machado, Renato Assis
       title: Social media and telemedicine for oral diagnosis and counselling in the COVID-19 era
        date: 2020-04-10
       words: 773
      flesch: 46
     summary: key: cord-291414-kyi8tfqd authors: Machado, Renato Assis; de Souza, Natália Lins; Oliveira, Rayane Maria; Martelli Júnior, Hercílio; Bonan, Paulo Rogério Ferreti title: Social media and telemedicine for oral diagnosis and counselling in the COVID-19 era date: 2020-04-10 journal: Oral Oncol DOI: 10.1016/j.oraloncology.2020.104685 sha: doc_id: 291414 cord_uid: kyi8tfqd nan Letter to editor Over the last years, there has been a significant improvement in the survival rate of patients with critical oral diseases, and this result is directly correlated to stage at initial presentation [1, 2] . Besides helping patients to control chronic diseases and to give an early diagnosis, the telemedicine can forward triage people with possible symptoms of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
    keywords: covid-19; patients; telemedicine
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        item: #3142 of 7819
          id: cord-291417-p49ukyhx
      author: Mikulska, Malgorzata
       title: Tocilizumab and steroid treatment in patients with COVID-19 pneumonia
        date: 2020-08-20
       words: 4449
      flesch: 38
     summary: Indeed, some real life experiences in COVID-19 patients showed that the use of antiinflammatory treatments might be beneficial [12] . The OW-weighted Cox proportional hazard regression model was used to calculate the adjusted hazard-ratio (HR OW ) of tocilizumab/methylprednisolone/SOC vs SOC patients.
    keywords: covid-19; days; failure; methylprednisolone; patients; pneumonia; soc; tocilizumab; treatment
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        item: #3143 of 7819
          id: cord-291443-ff80mr2a
      author: AlMutlak, Mohammed
       title: Future of Corneal Donation and Transplantation: Insights From COVID-19 Pandemic
        date: 2020-08-19
       words: 1588
      flesch: 45
     summary: At the end of the day, more research must be conducted on the true risk of viral transmission through donor corneal tissue. Eye banks may start to see push back from surgeons who are noticing a difference in donor tissue characteristics compared with what they were used to pre-COVID in part because of the decreased volume of available tissue and the increased time required for donor tissue screening.
    keywords: covid-19; donor; eye; tissue
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        item: #3144 of 7819
          id: cord-291476-c2i14ili
      author: Coe, William H.
       title: The Impact of COVID-19 on Inpatient Psychiatry Resident Supervision
        date: 2020-10-26
       words: 1077
      flesch: 42
     summary: As we seek to establish a new normal for inpatient psychiatry in the time of coronavirus, it is important to reflect on the relative strengths and weaknesses of our adapting systems on patient care and resident supervision. [1, 2] , but these are intended to be additive resources and do not directly address changes to clinical supervision or patient care as a result of the pandemic.
    keywords: pandemic; resident; supervision
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        item: #3145 of 7819
          id: cord-291483-ni6toh8c
      author: Kermani-Alghoraishi, Mohammad
       title: A Review of Venous Thromboembolism Phenomena in COVID-19 Patients
        date: 2020-08-28
       words: 1977
      flesch: 25
     summary: Therefore, in this review, the pathogens, epidemiology, diagnosis and therapeutic management of COVID-19 patients with VTE disease are discussed. The above theory could explain pulmonary embolism in COVID-19 patients who are not in critical condition.
    keywords: covid-19; disease; embolism; patients; pulmonary; vte
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        item: #3146 of 7819
          id: cord-291501-9dhldjjp
      author: Sarraf, David
       title: Is virtual existence our new reality?
        date: 2020-05-25
       words: 1490
      flesch: 57
     summary: New coronavirus infections are continuing at an unrelenting pace. Does it make sense therefore to continue to isolate communities when our hospitals are operating comfortably and infection rates are not abating?
    keywords: covid-19; crisis; face; world
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        item: #3147 of 7819
          id: cord-291505-vt5vpp60
      author: Rusconi, Chiara
       title: SARS-CoV-2 Interstitial Pneumonia Treated With Tocilizumab in a Patient Affected by Classical Hodgkin Lymphoma
        date: 2020-09-01
       words: 1776
      flesch: 31
     summary: Lung injury in COVID-19 patients probably reflects different pathophysiology patterns, and efficacy of tocilizumab is expected to be higher if ARDS is cytokine mediated; however, a reliable biomarker for differential diagnosis has not been identified yet. A single center experience Effective treatment of severe COVID-19 patients with tocilizumab Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China COVID-19 outcomes in patients with hematologic disease Tocilizumab, an anti-IL6 receptor antibody, to treat Covid-19-related respiratory failure: a case report First case of COVID-19 in a patient with multiple myeloma successfully treated with tocilizumab Recommendations for initial evaluation, staging, and response assessment of hodgkin and non-hodgkin lymphoma: The lugano classification Validation of a modified Early Warning Score in medical admissions Interpretation of guidelines for the diagnosis and treatment of novel coronavirus (2019-nCoV) infection by the National Health Commission (Trial Version 5) Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Early positron emission tomography response-adapted treatment in stage I and II hodgkin lymphoma: final results of the randomized EORTC/LYSA/FIL H10 trial Outcome of a patient with refractory Hodgkin lymphoma on pembrolizumab, infected with SARS-CoV-2 Tocilizumab not associated with increased infection risk after CAR T -Implications for COVID-19?
    keywords: cancer; covid-19; patients; sars; tocilizumab; treatment
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        item: #3148 of 7819
          id: cord-291526-aau0hnwx
      author: Ge, Fenfen
       title: Predicting Psychological State Among Chinese Undergraduate Students in the COVID-19 Epidemic: A Longitudinal Study Using a Machine Learning
        date: 2020-09-17
       words: 3452
      flesch: 43
     summary: In the present epidemic of COVID-19, the prevalence rate of probable anxiety and probable insomnia symptoms was 12.49% (GAD-7≥7) and 16.87% (ISI-7>14), respectively. We aimed to explore the prevalence rate of probable anxiety and probable insomnia and to find the risk factors among a longitudinal study of undergraduate students using the approach of machine learning.
    keywords: anxiety; covid-19; insomnia; items; students; study; symptoms; undergraduate
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        item: #3149 of 7819
          id: cord-291555-zapdk7gs
      author: Bertomeu-González, Vicente
       title: Estimulación cardiaca tras pandemia de la COVID-19. Propuesta de desescalada de la Sección de Estimulación Cardiaca de la Sociedad Española de Cardiología
        date: 2020-05-30
       words: 2776
      flesch: 29
     summary: La situación crítica vivida hasta pasar el pico de la pandemia obligó a la práctica paralización de toda la actividad no urgente y programada de nuestros centros sanitarios y a la puesta en marcha de medidas específicas y excepcionales, tanto para la protección de los profesionales como para la prevención de la diseminación de la infección en el ámbito sanitario. En el caso de la asistencia urgente, sus aspectos fundamentales incluyen una adecuada indicación de la necesidad de evaluación del dispositivo y la aplicación de las medidas de protección, tanto del personal sanitario como de los pacientes.
    keywords: cardiaca; con; contacto; covid-19; dec; del; estimulación; implante; las; los; pacientes; para; por; que; una
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        item: #3150 of 7819
          id: cord-291566-jwlvustd
      author: Wells Mulherin, Diana
       title: ASPEN Report on Nutrition Support Practice Processes With COVID‐19: The First Response
        date: 2020-07-16
       words: 5732
      flesch: 47
     summary: Other clinicians are reporting a decrease in new home PN patients over the past few months, and patients receiving home PN are unable to get routine procedures and diagnostic tests. Information to support home PN patients is generally available electronically, such as medical records, patient laboratory results, and education information, and thus minimal changes to workflows were needed.
    keywords: care; clinicians; covid-19; home; hospital; nutrition; patients; support; team; time; use
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        item: #3151 of 7819
          id: cord-291581-oyhzot4z
      author: Malik, Fazila-Tun-Nesa
       title: Clinical Presentation, Management and In-Hospital Outcome of Healthcare Personnel With COVID-19 Disease
        date: 2020-08-24
       words: 2773
      flesch: 54
     summary: HCP employed in this hospital who experienced fever or respiratory symptoms or came in close contact with COVID-19 patients at home or their workplace were included in this study. As they frequently have contact with COVID-19 patients and also have asymptomatic cases, periodic testing for COVID-19 among HCP is recommended to prevent further spread.
    keywords: cov-2; covid-19; hcp; infection; patients; symptoms
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        item: #3152 of 7819
          id: cord-291585-a6y8k1a5
      author: Kow, Chia Siang
       title: The use of antiplatelet agents for arterial thromboprophylaxis in COVID-19
        date: 2020-08-28
       words: 271
      flesch: 23
     summary: Based on the reported findings, we observed that the proportion of COVID-19 patients with major cardiovascular risk factors who developed acute arterial thrombosis is higher than that of their non-COVID-19 counterparts. Therefore, we would like to propose routine antiplatelet therapy (low-dose aspirin, clopidogrel, ticagrelor, prasugrel, ticlopidine, and dipyridamole) for arterial thromboprophylaxis in COVID-19 patients who are deemed at heightened risk for the development of acute arterial thrombosis.
    keywords: covid-19
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        item: #3153 of 7819
          id: cord-291588-tp89j1kk
      author: Dorche, Maryam Sharifian
       title: Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic
        date: 2020-08-07
       words: 5613
      flesch: 31
     summary: Front Public Health Acute Vision Loss in a Patient with COVID-19 Olfactory and Gustatory Dysfunction in a COVID-19 Patient with Ankylosing Spondylitis Treated with Etanercept: Case Report Quantitative evaluation of olfactory dysfunction in hospitalized patients with Coronavirus [2] (COVID-19) Bilateral transient olfactory bulbs edema during COVID-19-related anosmia Anosmia and olfactory tract neuropathy in a case of COVID-19 Magnetic Resonance Imaging Alteration of the Brain in a Patient With Coronavirus Disease 2019 (COVID-19) and Anosmia Olfactory Bulb Magnetic Resonance Imaging in SARS-CoV-2-Induced Anosmia: The First Report Prevalence and Duration of Acute Loss of Smell or Taste in COVID-19 Patients Anosmia and ageusia: common findings in COVID-19 patients younger age in ambulatory settings -a multicenter cross-sectional study COVID-19 presenting with ophthalmoparesis from cranial nerve palsy COVID-19 and herpes zoster co-infection presenting with trigeminal neuropathy Pearls and Oy-sters: Facial nerve palsy as a neurological manifestation of Covid-19 infection Guillain Barre syndrome associated with COVID-19 infection: A case report Early Guillain-Barré syndrome in coronavirus disease 2019 (COVID-19): a case report from an Italian COVID-hospital COVID-19 may induce Guillain-Barré syndrome Guillain-Barré syndrome related to COVID-19 infection Guillain-Barré syndrome associated with SARS-CoV-2 infection: causality or coincidence? Covid-19 and Guillain-Barré syndrome: More than a coincidence! In COVID-19 patients, possible mechanisms include infections, parenchymal damages, electrolyte imbalance, hypoxic, toxic and metabolic encephalopathies and non-convulsive status epilepticus.
    keywords: acute; barré; case; coronavirus; cov-2; covid-19; disease; guillain; infection; patients; sars; studies; syndrome
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        item: #3154 of 7819
          id: cord-291595-8241pjpe
      author: Mahmudpour, Mehdi
       title: COVID-19 cytokine storm: The anger of inflammation
        date: 2020-05-30
       words: 5861
      flesch: 36
     summary: The first case of COVID-19 treated with the complement C3 inhibitor AMY-101 Angiotensin II stimulates canonical TGF-β signaling pathway through angiotensin type 1 receptor to induce granulation tissue contraction COVID-19: a case for inhibiting IL-17? Principles of separation: indications and therapeutic targets for plasma exchange Roles of angiotensin peptides and recombinant human ACE2 in heart failure Recombinant human ACE2: acing out angiotensin II in ARDS therapy Angiotensin-converting enzyme 2 in acute respiratory distress syndrome Angiotensinconverting enzyme 2 inhibits lung injury induced by respiratory syncytial virus Prosper, Inhibition of SARS-CoV-2 infections in engineered human tissues using clinicalgrade soluble human N-methylacetamide, fumarate (LF22-0542), a novel nonpeptidic bradykinin B1 receptor antagonist From bradykinin B2 receptor antagonists to orally active and selective bradykinin B1 receptor antagonists Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria Many drugs for many targets: novel treatments for complement-mediated glomerular disease Soluble CR1 therapy improves complement regulation in C3 glomerulopathy Increased activity of the RAAS system occurs in the COVID-19 induced cytokine storm. It is a state of out-of-control release of a variety of inflammatory cytokines.
    keywords: ace2; activation; angiotensin; axis; complement; cov-2; covid-19; cytokine; lung; receptor; sars; storm; system
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        item: #3155 of 7819
          id: cord-291612-j7xz1qaz
      author: Albahri, O.S.
       title: Systematic Review of Artificial Intelligence Techniques in the Detection and Classification of COVID-19 Medical Images in Terms of Evaluation and Benchmarking: Taxonomy Analysis, Challenges, Future Solutions and Methodological Aspects
        date: 2020-07-01
       words: 10220
      flesch: 37
     summary: However, in this regard, there are no suggested solutions to handle these particular issues in terms of evaluation and benchmarking of COVID-19 AI classification techniques. To evaluate and benchmark AI classification techniques used in the detection of COVID-19 medical images, the present study recommends to integrate AHP for assigning weights for the evaluation criteria of each classification type subjectively by relying on the judgment of experts, and VIKOR is needed to offer a comprehensive ranking of COVID-19 AI classification techniques.
    keywords: ai techniques; benchmarking; classification; classification techniques; covid-19; covid-19 classification; criteria; decision; detection; evaluation; evaluation criteria; images; multi; process; review
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        item: #3156 of 7819
          id: cord-291613-pfgy9ztl
      author: Farshidpour, Maham
       title: A brief review of liver injury in patients with Corona Virus Disease-19 during the pandemic
        date: 2020-07-03
       words: 1540
      flesch: 29
     summary: All patient 34 Total , receiving antihypertensive medication, and had diabetes (median HbA 1c of 6·9%).They suggested liver transplant patients with metabolic comorbidities should be monitored closely, and also in concordance with the American Association for the Study of Liver Diseases, immunosuppression therapy should not be reduced or discontinued in asymptomatic recipients of liver transplant [26, 27] . Liver enzymes are often elevated in COVID-19 patients, signifying liver damage.
    keywords: coronavirus; covid-19; injury; liver; patients
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        item: #3157 of 7819
          id: cord-291624-fod0eyuj
      author: Malone, Robert W.
       title: COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms
        date: 2020-06-22
       words: 6508
      flesch: 35
     summary: This modeling demonstrated that the different clinical outcomes exhibited by COVID-19 patients taking famotidine vs. cimetidine could be readily explained by the distinctive pharmacokinetic and pharmacodistribution properties of the two agents. It is towards the end of the rst week of symptoms that COVID-19 patients develop shortness of breath (SOB).
    keywords: activation; activity; cell; cimetidine; coronavirus; cov-2; covid-19; disease; famotidine; figure; histamine; infection; mast; patients; receptor; sars; symptoms; syndrome
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        item: #3158 of 7819
          id: cord-291627-5dqwyd9r
      author: Yadav, Rakhee
       title: SARS-CoV-2-host dynamics: Increased risk of adverse outcomes of COVID-19 in obesity
        date: 2020-07-21
       words: 4367
      flesch: 40
     summary: However, whether obesity, over and above its cardio-metabolic co-morbidities might independently contribute to COVID-19 risk; needs more robust and detailed prospective survey. 25 Several reports from around the world identified obesity and severe obesity as risk factors for hospitalization and mechanical ventilation.
    keywords: adipose; coronavirus; covid-19; disease; infection; influenza; obesity; patients; risk; sars; tissue
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        item: #3159 of 7819
          id: cord-291638-oatrjbo3
      author: Kang, Dayun
       title: Spatial epidemic dynamics of the COVID-19 outbreak in China
        date: 2020-04-03
       words: 2639
      flesch: 56
     summary: Third, it only investigated spatial spread in mainland China. Spatial analysis is of great help in understanding the spread of infectious diseases, and spatial association was the key to the spatial spread during the early stages of the COVID-19 pandemic in mainland China.
    keywords: cases; china; covid-19; number; spread
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        item: #3160 of 7819
          id: cord-291644-5y0ioety
      author: Akiyama, Tomohiro
       title: The Natural-Mineral-Based Novel Nanomaterial IFMC Increases Intravascular Nitric Oxide without Its Intake: Implications for COVID-19 and beyond
        date: 2020-08-29
       words: 5841
      flesch: 36
     summary: No problem was found in the monitoring results when spraying IFMC solution on the body or when wearing clothes impregnated with IFMC over several months. We think that mineral components exist as ions in IFMC solution since crystals were obtained when it dried up.
    keywords: blood; blood flow; body; covid-19; flow; ifmc; increase; intravascular; nitric; oxide; potential; rate; surface; temperature; therapy; vasodilation
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        item: #3161 of 7819
          id: cord-291661-hn1z0817
      author: Wood, David A.
       title: Precautions and Procedures for Coronary and Structural Cardiac Interventions during the COVID-19 Pandemic: Guidance from Canadian Association of Interventional Cardiology
        date: 2020-03-24
       words: 1218
      flesch: 29
     summary: This pandemic has placed considerable stress on health care resources and providers. This pandemic has placed considerable stress on health care resources and providers.
    keywords: care; covid-19; pandemic; patients
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        item: #3162 of 7819
          id: cord-291686-kgewmqg5
      author: Patel, Surendra
       title: Prioritizing cardiovascular surgical care in COVID‐19 pandemic: Shall we operate or defer?
        date: 2020-07-15
       words: 1621
      flesch: 39
     summary: After reviewing a few available guidelines regarding cardiovascular surgery in COVID‐19, we conclude to perform only those surgeries which cannot be deferred to a certain period of time, to reduce the burden of the health care system of the country, provide optimal care to patients with COVID‐19, and to protect health care workers and cardiovascular patients from COVID‐19. Cardiovascular patients have a greater risk of acquiring COVID-19 infection, with morbidity and mortality much more in these patients in comparison to healthy individuals.
    keywords: covid-19; pandemic; patients; surgery
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        item: #3163 of 7819
          id: cord-291687-kwu0otpi
      author: Judson, Gregory L.
       title: Cardiovascular Implications and Therapeutic Considerations in COVID-19 Infection
        date: 2020-06-13
       words: 5583
      flesch: 34
     summary: The initial cohort study of COVID-19 patients included data from 552 hospitals in China with 1099 patients with COVID-19 disease [17] . Initial reports of myocarditis from China described cases of cardiogenic shock and reduced left ventricular ejection fraction among COVID-19 patients [37, 38] .
    keywords: acute; cardiac; china; coronavirus; cov-2; covid-19; disease; infection; injury; mortality; patients; sars
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        item: #3164 of 7819
          id: cord-291697-wpnq9wc0
      author: Riechelmann, Rachel P
       title: Evidence-based recommendations for gastrointestinal cancers during the COVID-19 pandemic by the Brazilian Gastrointestinal Tumours Group
        date: 2020-05-22
       words: 5873
      flesch: 39
     summary: A meta-analysis Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as firstline treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study Capecitabine and oxaliplatin for advanced esophagogastric cancer Capecitabine plus oxaliplatin compared with fluorouracil and folinic acid as adjuvant therapy for stage III colon cancer ESMO recommendations on microsatellite instability testing for immunotherapy in cancer, and its relationship with PD-1/PD-L1 expression and tumour mutational burden: a systematic review-based approach A six-weekly (Q6W) dosing schedule for pembrolizumab based on an exposure-response (E-R) evaluation using modeling and simulation American College of Surgeons COVID-19: guidance for triage of non-emergent surgical procedures Staging investigations for oesophageal cancer: a meta-analysis Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a r Lancet Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial Optimal timing for postsurgical adjuvant therapy in patients with gastric cancer: a propensity score matching study Chemoradiotherapy versus chemoradiotherapy plus surgery for esophageal cancer Cochrane database Syst Rev 8 CD010511 Pembrolizumab versus chemotherapy as second-line therapy for advanced esophageal cancer: phase III KEYNOTE-181 study Clinical Oncology COVID-19 Provider & Practice Information Centers for Disease Control and Prevention Interim Infection Prevention and Control Recommendations for Patients with Suspected or Confirmed Coronavirus Disease Individual patient data meta-analysis of the value of microsatellite instability as a biomarker in gastric cancer PET-PANC: multicentre prospective diagnostic accuracy and health economic analysis study of the impact of combined modality 18fluorine-2-fluoro-2-deoxy-d-glucose positron emission tomography with computed tomography scanning in the diagnosis and managemen Neoadjuvant herapy followed by resection versus upfront resection for resectable pancreatic cancer: a propensity score matched analysis Preoperative chemoradiotherapy versus immediate surgery for resectable and borderline resectable pancreatic cancer: results of the Dutch Randomized Phase III PREOPANC Total neoadjuvant therapy with FOLFIRINOX followed by individualized chemoradiotherapy for borderline resectable pancreatic adenocarcinoma: a phase 2 clinical trial FOLFIRINOX or gemcitabine as adjuvant therapy for pancreatic cancer Adjuvant chemotherapy with gemcitabine and long-term outcomes among patients with resected pancreatic cancer: the CONKO-001 randomized trial FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine FOLFIRINOX until progression, FOLFIRINOX with maintenance treatment, or sequential treatment with gemcitabine and FOLFIRI.3 for first-line treatment of metastatic pancreatic cancer: a randomized phase II trial (PRODIGE 35-PANOPTIMOX) Randomized, multicenter, phase II rial of gemcitabine and cisplatin with or without veliparib in patients with pancreas adenocarcinoma and a germline BRCA/PALB2 mutation Capecitabine compared with observation in resected biliary tract cancer (BILCAP): a randomised, controlled, multicentre, phase 3 study Cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer American Association of Transplantation 2019-nCoV (Coronavirus): FAQs for Organ Donation and Transplantation Utility of positron emission tomography-computed tomography scan in detecting residual hepatocellular carcinoma post treatment: Series of case reports IMbrave150: a randomized phase III study of 1L atezolizumab plus bevacizumab vs sorafenib in locally advanced or metastatic hepatocellular carcinoma Lenvatinib versus sorafenib in first-line treatment of patients with unresectable hepatocellular carcinoma: a randomised phase 3 non-inferiority trial Sorafenib in advanced hepatocellular carcinoma Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled Regorafenib dose-optimisation in patients with refractory metastatic colorectal cancer (ReDOS): a randomised, multicentre, open-label, phase 2 study Ramucirumab after sorafenib in patients with advanced hepatocellular carcinoma and increased α-fetoprotein concentrations (REACH-2): a randomised, double-blind, placebo-controlled Safety and efficacy of sorafenib in patients with Child-Pugh B advanced hepatocellular carcinoma Guidelines for the management of neuroendocrine tumours by the Brazilian gastrointestinal tumour group Ecancermedicalscience 11 716 Sunitinib malate for the treatment of pancreatic neuroendocrine tumors A randomized study of temozolomide or temozolomide and capecitabine in patients with advanced pancreatic neuroendocrine tumors: a trial of the ECOG-ACRIN Cancer Research Group (E2211) Opportunist and serious infections in patients with neuroendocrine tumours treated with everolimus: a multicenter study of real world patients International expert consensus statement regarding radiotherapy treatment options for rectal cancer during the COVID 19 pandemic Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial Randomized phase II trial of chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: CAO/ARO/AIO-12 Long-course oxaliplatin-based preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for cT4 or fixed cT3 rectal cancer: results of a randomized phase III study Total neoadjuvant therapy with short course radiation compared to concurrent chemoradiation in rectal cancer Achieving a complete clinical response after neoadjuvant chemoradiation that does not require surgical resection: it may take longer than you think! However, few data on the outcomes of cancer patients infected by SARS CoV-2 exist.
    keywords: cancer; chemotherapy; clinical; covid-19; disease; eor; metastatic; neoadjuvant; patients; phase; recommendations; surgery; treatment; tumours
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        item: #3165 of 7819
          id: cord-291709-x9llke60
      author: Lin, Yulan
       title: Uncovering physical and attitudinal barriers to adherence to precautions for preventing the transmission of COVID-19 and anxiety level of people in Wuhan: 2 months after the lockdown
        date: 2020-09-22
       words: 2579
      flesch: 48
     summary: High anxiety levels even after the peak warrant serious attention. In contrast to physical prevention measures, the older adults in this study 253 demonstrated higher negative attitudes toward COVID-19.
    keywords: anxiety; covid-19; levels; outbreak; score
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        item: #3166 of 7819
          id: cord-291719-1ku6cmwj
      author: Hajjo, Rima
       title: A Systems Biology Workflow for Drug and Vaccine Repurposing: Identifying Small-Molecule BCG Mimics to Reduce or Prevent COVID-19 Mortality
        date: 2020-10-06
       words: 6506
      flesch: 27
     summary: Our analysis demonstrates that BCG vaccine affects the production and maturation of naïve T cells resulting in enhanced, long-lasting trained innate immune responses that can provide protection against novel viruses. A consensus gene signature for BCG vaccine was derived from gene expression profiles in peripheral blood mononuclear cells (PBMCs) in response to a BCG challenge test reported by Matsumiya et al (76) , GSE58636 dataset on NCBI Gene Expression Omnibus (GEO) (27) .
    keywords: bcg; cells; cgs; cov-2; covid-19; effects; expression; gene; network; protein; response; sars; study; vaccination; vaccine
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        item: #3167 of 7819
          id: cord-291724-bwiyp73e
      author: Abdulmajeed, Kabir
       title: ONLINE FORECASTING OF COVID-19 CASES IN NIGERIA USING LIMITED DATA
        date: 2020-05-08
       words: 1923
      flesch: 51
     summary: The outcomes of these efforts are expected to provide academic thrust in guiding the policymakers in the deployment of containment strategies and/or assessment of containment interventions in stemming the spread of the disease in Nigeria Decision Sciences Application of an online framework for forecasting the range of COVID-19 cases in Nigeria using limited data. Data on the daily number of COVID-19 cases in Nigeria were automatically mined from the NCDC and Wikipedia websites every 24 hours.
    keywords: cases; covid-19; data; model; nigeria
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        item: #3168 of 7819
          id: cord-291735-b6dksrbx
      author: Sukut, Ozge
       title: The impact of COVID‐19 pandemic on people with severe mental illness
        date: 2020-09-19
       words: 1735
      flesch: 37
     summary: The Lancet Patients with mental health disorders in the COVID-19 epidemic Iranian mental health during the COVID-19 epidemic Progression of mental health services during the COVID-19 outbreak in China Risk of pneumonia and pneumococcal disease in people with severe mental illness: English record linkage studies The risk and prevention of novel coronavirus pneumonia infections among inpatients in psychiatric hospitals Seasonal flu guidance for 2019 to 2020 for healthcare and custodial staff in prisons, immigration removal centers and other prescribed places of detention for adults in England Outbreak of pandemic virus (H1N1) 2009 in a residence for mentally disabled persons in Balearic Island Mental health status of people isolated due to Middle East Respiratory Syndrome COVID-19 in people with mental illness: challenges and vulnerabilities Caring for persons in detention suffering with mental illness during the Covid-19 outbreak Psychological interventions for people affected by the COVID-19 epidemic Mortality and medical comorbidity in the severely mentally ill: a German registry study Mental illness and metabolic syndrome-a literature review Comorbidity of mental and physical diseases: a main challenge for medicine of the 21st century Addressing the COVID-19 pandemic in populations with serious mental illness Smoking or vaping may increase the risk of severe coronavirus infection COVID-19: a potential public health problem for homeless populations Expert consensus on managing pathway and coping strategies for patients with mental disorders during prevention and control of infectious disease outbreak Psychosomatic health service intervention plan for the prevention and control of new coronavirus infection and pneumonia Understanding the effect on individuals with mental health illness of the outbreak, it is necessary and important to protect these individuals who are a vulnerable group and provide the health services they need.
    keywords: covid-19; health; illness; individuals
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        item: #3169 of 7819
          id: cord-291745-2371k29o
      author: Ha, Kyoo-Man
       title: A Lesson Learned from the Outbreak of COVID-19 in Korea
        date: 2020-05-14
       words: 1115
      flesch: 42
     summary: In doing so, he must understand the basic process of COVID-19 management by consulting all stakeholders in the field of emergency management. A divided community approach involves emergency management stakeholders individually understanding, evaluating, and then deciding on steps regarding managing the outbreak of COVID-19.
    keywords: community; covid-19; emergency
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        item: #3170 of 7819
          id: cord-291756-ejh1r8h4
      author: Pérez-Fuentes, María del Carmen
       title: Threat of COVID-19 and emotional state during quarantine: Positive and negative affect as mediators in a cross-sectional study of the Spanish population
        date: 2020-06-25
       words: 3769
      flesch: 44
     summary: There was a direct positive effect of perceived threat from COVID-19 on sadness-depression, anxiety and anger-hostility moods, while anxiety and anger-hostility had a direct positive effect on perception of threat from the virus. Thus, there was a circular relationship, in which perceived threat influenced the presence of negative mood, and negative mood, in turn, linked to emotions of irritation and agitation from a present situation, promoted the feeling of threat.
    keywords: affect; anxiety; balance; covid-19; mood; perception; state; threat
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        item: #3171 of 7819
          id: cord-291768-68xr2ycm
      author: Bankole, Taofik Olatunji
       title: Low incidence of COVID-19 in the West African sub-region: mitigating healthcare delivery system or a matter of time?
        date: 2020-10-17
       words: 5960
      flesch: 53
     summary: However, while the highest number of reported COVID-19 cases was recorded in Tn+1 (1000%), the lowest growth in the spread of the infection was reported in Tn+4 (54.1%). In fact, as of April 18, 2020, with the exception of South Africa, no country in the sub-region has yet reached 2000 reported COVID-19 cases since the outbreak in December 2019.
    keywords: africa; cases; covid-19; deaths; growth; rate; region; west
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        item: #3172 of 7819
          id: cord-291770-xqp4labe
      author: Attwood, Sophie
       title: How will the COVID-19 pandemic shape the future of meat consumption?
        date: 2020-08-12
       words: 2826
      flesch: 47
     summary: Zoonotic diseases The Next Pandemic is Already Coming, Unless Humans Change How We Interact with Wildlife, Scientists Say Dissociating meat from its animal origins: a systematic literature review Tomatoes grow underground and pasta comes from animals, according to UK school children and teens Consumer perceptions of meat production: enhancing the competitiveness of British agriculture by understanding communication with the consumer Consumer attitudes towards environmental concerns of meat consumption: a systematic review Five eays that coronavirus will change the way we eat Wet markets' likely launched the coronavirus. key: cord-291770-xqp4labe authors: Attwood, Sophie; Hajat, Cother title: How will the COVID-19 pandemic shape the future of meat consumption? date: 2020-08-12 journal: Public health nutrition DOI: 10.1017/s136898002000316x sha: doc_id: 291770 cord_uid: xqp4labe Since its recent onset, the COVID-19 pandemic has altered the daily lives of millions around the world.
    keywords: animals; consumer; covid-19; food; health; meat; pandemic; term
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        item: #3173 of 7819
          id: cord-291773-m65bhfzt
      author: Helton, Gabrielle
       title: “Definitely Mixed Feelings:” The effect of COVID-19 on bereavement in parents of children who died from cancer
        date: 2020-09-02
       words: 3259
      flesch: 59
     summary: The Grief of Parents After the Death of a Young Child Helping parents live with the hole in their heart: The role of health care providers and institutions in the bereaved parents' grief journeys Bereavement Follow-Up After the Death of a Child as a Standard of Care in Pediatric Oncology A qualitative study of advice from bereaved parents and siblings Providers and hospitals should proactively contact bereaved parents to assess for the need of additional support and find innovative ways to connect and provide ongoing support for parents and families.
    keywords: bereavement; covid-19; pandemic; parents; support
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        item: #3174 of 7819
          id: cord-291803-hsnz2qry
      author: Bhattacharjee, Barnali
       title: “The COVID-19 Pandemic and its Effect on Mental Health in USA – A Review with Some Coping Strategies”
        date: 2020-08-23
       words: 4038
      flesch: 49
     summary: The fear of being infected or dying from the disease is one of the most significant causes of mental health disorders. All of the factors mentioned above contribute towards mental health disorders among people.
    keywords: covid-19; disorders; fear; health; healthcare; pandemic; people; states; united
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        item: #3175 of 7819
          id: cord-291809-b7sosrc7
      author: Iacovoni, Attilio
       title: A case series of Novel-Coronavirus infection in heart transplantation from two centers in the pandemic area in the North of Italy
        date: 2020-06-26
       words: 2487
      flesch: 48
     summary: We here report a series of heart transplanted patients with COVID-19 from two centers of Italy. RESULTS From February to March 2020 twenty-six heart transplanted patients (age 62±12 years; 77% males; time from transplant 10±10 years; 69% with comorbidities) had a microbiologically confirmed COVID-19.
    keywords: clinical; covid-19; heart; patients; sars; transplant
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        item: #3176 of 7819
          id: cord-291820-x4a4c4pv
      author: Nogueira, Marcelo Saito
       title: Ultraviolet-based biophotonic technologies for control and prevention of COVID-19, SARS and related disorders
        date: 2020-06-22
       words: 1105
      flesch: 24
     summary: With this in mind, this letter focuses on encouraging researchers and companies to develop safe and reliable ultraviolet (UV) light technology to be used for decontamination of PPE as well as environmental surface disinfection, food safety, possible production vaccines based on ultraviolet-inactivated SARS-CoV-2 (the cause of COVID-19) and SARS-CoV. Practical aspects of designing novel UV technology are discussed along with the context of the technological need of each application. UV light technology has potential to make the future brighter to everyone.
    keywords: covid-19; equipment; safety; sars
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        item: #3177 of 7819
          id: cord-291829-lyg6i2wv
      author: Alcázar-Navarrete, Bernardino
       title: Management and follow up of respiratory patients in the post-Covid-19 era: Are we ready yet?()
        date: 2020-09-06
       words: 601
      flesch: 39
     summary: key: cord-291829-lyg6i2wv authors: Alcázar-Navarrete, Bernardino; Molina-París, Jesús; Martín-Sánchez, Francisco Javier title: Management and follow up of respiratory patients in the post-Covid-19 era: Are we ready yet?() date: 2020-09-06 journal: Arch Bronconeumol DOI: 10.1016/j.arbr.2020.08.005 sha: doc_id: 291829 cord_uid: lyg6i2wv nan To the Editor: Health systems have already changed all over the world, and the effects of the situation will continue to influence how we will manage respiratory diseases and, more specifically, how we will monitor patients with these diseases.
    keywords: covid-19; patients
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        item: #3178 of 7819
          id: cord-291849-cjeyz86e
      author: Baidal, Jennifer Woo
       title: Social Determinants of Health and COVID-19 Among Patients in New York City
        date: 2020-09-15
       words: 1585
      flesch: 46
     summary: To align with publicly available maps of New York City which display data by zip code, zip codes were used to map the proportion of negative tests; proportion of New York City Covid-19 cases attributable to NYP patients [4] ; proportion of NYP cases hospitalized without death; and death-to-case ratio to map using ArcGIS ArcMap (Version 10.6.1. In sum, among this cohort of over 20,000 patients in New York City, variation in Covid-19 test results and disease outcomes according to age, sex, race/ethnicity, insurance status, and neighborhood characteristics was identi ed.
    keywords: covid-19; new; outcomes; patients
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        item: #3179 of 7819
          id: cord-291851-xesef17i
      author: Wong, Yu-Jun
       title: A systematic review and meta-analysis of the COVID-19 associated liver injury
        date: 2020-08-31
       words: 4386
      flesch: 47
     summary: The objective of this meta-analysis is to compare the risk and clinical outcome of COVID-19 associated liver injury between COVID-19 patients with severe and non-severe COVID-19. COVID-19 associated liver injury is defined as any liver damage in patients COVID-19 patients, with or without the pre-existing liver disease [5] .
    keywords: analysis; covid-19; disease; injury; liver; patients; studies
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        item: #3180 of 7819
          id: cord-291862-8c48m5hf
      author: Rahi, Manju
       title: Novel Coronavirus Disease (COVID-19) Mitigation Steps Provide a Blueprint for Malaria Control and Elimination
        date: 2020-05-07
       words: 2066
      flesch: 40
     summary: 5 A recent modeling analysis by the WHO on the impact of COVID-19 on malaria control in sub-Saharan Africa predicts a > 20% rise in malaria cases and a doubling of malaria deaths, driven by 75% reduction in both routine ITN distribution and access to antimalarials. Nonetheless, we feel that the best facets of COVID-19 public health management can become new guiding principles in malaria-endemic countries to improve malaria control and hasten malaria elimination.
    keywords: control; countries; covid-19; elimination; health; malaria
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        item: #3181 of 7819
          id: cord-291886-phl8kh3f
      author: Anthi, Anastasia
       title: A Severe COVID-19 Case Complicated by Right Atrium Thrombus
        date: 2020-09-23
       words: 1988
      flesch: 31
     summary: In addition, the low number of associated deep venous thromboses in COVID-19 patients may suggest the presence of pulmonary thrombosis rather than embolism Circulation Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Pulmonary embolism in COVID-19 patients: Awareness of an increased prevalence Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospi Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Routine venous thromboembolism prophylaxis may be inadequate in the hypercoagulable state of severe coronavirus disease 2019 COVID-19 and thrombotic complications: Pulmonary thrombosis rather than embolism? Thrombosis and COVID-19 pneumonia:
    keywords: anticoagulation; covid-19; icu; patient; thrombus
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        item: #3182 of 7819
          id: cord-291916-5yqc3zcx
      author: Hozhabri, Hossein
       title: The Global Emergency of Novel Coronavirus (SARS-CoV-2): An Update of the Current Status and Forecasting
        date: 2020-08-05
       words: 16799
      flesch: 39
     summary: This form of adaptation required a series of amino acid changes in the RBD within the S protein of SARS viruses that circulated in bats [56, 68] . Strategies for controlling emerging coronaviruses A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice Cross-species transmission of the newly identified coronavirus 2019-nCoV Towards a solution to MERS:
    keywords: ace2; acute; cases; cell; china; coronavirus; cov-2; covid-19; days; diagnosis; disease; figure; genome; host; human; infection; mers; novel; patients; pneumonia; protein; receptor; rna; sars; study; symptoms; syndrome; transmission; vaccine
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        item: #3183 of 7819
          id: cord-291954-wormplcu
      author: Sakulkonkij, Parichart
       title: A family cluster of diagnosed coronavirus disease 2019 (COVID‐19) kidney transplant recipient in Thailand
        date: 2020-08-08
       words: 4433
      flesch: 41
     summary: The majority of COVID-19 patients in the general population have leukopenia with lymphocytopenia (70%) as similar to transplant recipients. A familial cluster, including a kidney transplant recipient Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV Postdischarge surveillance and positive virus detection in two medical staff recovered from coronavirus disease 2019 (COVID-19), China Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Factors associated with prolonged viral shedding in patients with avian influenza A(H7N9) virus infection Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia Improved molecular diagnosis of COVID-19 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse transcription-PCR assay validated in vitro and with clinical specimens Laboratory diagnosis of COVID-19: current issues and challenges Detection of SARS-CoV-2 in different types of clinical specimens Early clinical and CT manifestations of coronavirus disease 2019 (COVID-19) pneumonia Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study Frequency and distribution of chest radiographic findings in COVID-19 positive patients Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19.
    keywords: case; coronavirus; covid-19; disease; patients; pneumonia; recipients; sars; transplant
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        item: #3184 of 7819
          id: cord-292002-g0v0xc21
      author: Yang, Wenjing
       title: The role of imaging in 2019 novel coronavirus pneumonia (COVID-19)
        date: 2020-04-15
       words: 4657
      flesch: 40
     summary: In a large research cohort study, chest CT findings showed a bilateral distribution of patchy ground glass opacity and consolidation in 138 patients [26] . Imaging features of multiple patchy areas of ground glass opacity and consolidation predominately in the periphery of the lungs are characteristic manifestations on chest CT and extremely helpful in the early detection and diagnosis of this disease, which aids prompt diagnosis and the eventual control of this emerging global health emergency.
    keywords: 2019; chest; coronavirus; covid-19; glass; ground; novel; pneumonia
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        item: #3185 of 7819
          id: cord-292015-pfvgpf7v
      author: Brouwer, A. F.
       title: SARS-CoV-2 surveillance in decedents in a large, urban medical examiner's office
        date: 2020-08-07
       words: 2916
      flesch: 48
     summary: Seven-day average percent positivity among flagged decedents closely matched the trajectory of percent positivity in the catchment population, particularly during the peak of the outbreak (March and April). Decedents were assessed for possible recent COVID-19 illness through a checklist (presumptive or confirmed COVID-19 diagnosis; signs of infection (fever, shortness of breath, sneezing, coughing, chest pain, body aches); recent travel; contacts, family, or friends with suspected or confirmed COVID-19 diagnosis or signs of infection), and flagged decedents (i.e., those with one or more of the listed items) were swabbed preferentially.
    keywords: cov-2; covid-19; decedents; preprint; sars
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        item: #3186 of 7819
          id: cord-292030-cjz4nuag
      author: Qiu, Guangyu
       title: Dual-Functional Plasmonic Photothermal Biosensors for Highly Accurate Severe Acute Respiratory Syndrome Coronavirus 2 Detection
        date: 2020-04-13
       words: 5694
      flesch: 41
     summary: In the LSPR sensing path, the collimated wide spectrum beam passed through the aperture-iris (I1/I2), the linear polarizers (P1/P2), the birefringent crystal (BC), and totally reflected at the interface of AuNI-dielectric for LSPR detection. The impacts of the localized thermoplasmonic heating on nucleic acids hybridization and LSPR detection were systematically studied.
    keywords: auni; cov-2; covid; detection; figure; lspr; plasmonic; ppt; rdrp; sars; sequence; temperature
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        item: #3187 of 7819
          id: cord-292041-a65kfw80
      author: Orienti, Isabella
       title: Pulmonary Delivery of Fenretinide: A Possible Adjuvant Treatment in COVID-19
        date: 2020-05-27
       words: 6133
      flesch: 29
     summary: Pulmonary formulations of anti-inflammatory drugs could represent a good option in combination with systemic antiviral drugs or glucocorticoids. It decreased the infiltration of inflammatory cells and inhibited the production of inflammatory cytokines [84] .
    keywords: activity; cells; cov; cov-2; covid-19; drugs; fenretinide; infection; lung; pulmonary; response; sars; treatment; virus
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        item: #3188 of 7819
          id: cord-292054-x0saq938
      author: Hashizume, Misato
       title: Outlook of IL-6 signaling blockade for COVID-19 pneumonia
        date: 2020-10-05
       words: 3801
      flesch: 37
     summary: In the USA, FDA declared the emergency use authorization for use of IL-6 immunoassay for COVID-19 patients [32] . Additionally, no new safety findings were observed with the use of sarilumab in COVID-19 patients [48] .
    keywords: cell; covid-19; il-6; patients; phase; pneumonia; study; tocilizumab; treatment
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        item: #3189 of 7819
          id: cord-292056-dtdyxhq4
      author: Ghogawala, Zoher
       title: Editorial. COVID-19 and spinal surgery
        date: 2020-04-17
       words: 1396
      flesch: 44
     summary: As elective surgery has been reduced in hospitals, many spinal surgeons have been asked to participate in the care of medical patients. The mortality rates have been higher in Spain and Italy, and the numbers of infected patients have overwhelmed hospitals.
    keywords: covid-19; patients; spinal; surgeons; surgery
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        item: #3190 of 7819
          id: cord-292100-3ls0po4k
      author: Krishna, Sanjeev
       title: Repurposing antimalarials to tackle the COVID-19 pandemic
        date: 2020-10-19
       words: 1577
      flesch: 32
     summary: Artemisinins have also shown anti-inflammatory effects, including inhibition of interleukin-6 that plays a key role in the development of severe COVID-19. The RECOVERY trial has shown a mortality benefit of dexamethasone in patients with moderate and severe COVID-19, supporting the importance of anti-inflammatory interventions to manage the complications of CRS.
    keywords: artesunate; covid-19; factor; il-6; patients; sars
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        item: #3191 of 7819
          id: cord-292144-jprbp1ua
      author: Song, Haitao
       title: Using traveller-derived cases in Henan Province to quantify the spread of COVID-19 in Wuhan, China
        date: 2020-08-04
       words: 3875
      flesch: 52
     summary: [8] estimated the number of cases in Wuhan city by 18th January. μ (b) is μ 1 (b 1 ) before January 23 and 0 after January 23 because that Wuhan city travel was banned on January 23.
    keywords: cases; covid-19; january; people; province; wuhan
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        item: #3192 of 7819
          id: cord-292156-chmyzmq0
      author: Battiato, Concetto
       title: Impact of Coronavirus Disease 2019 (COVID-19) on the epidemiology of orthopedics trauma in a region of central Italy
        date: 2020-10-02
       words: 758
      flesch: 41
     summary: Future studies with a larger number of patients and a longer observation period are needed to evaluate the real impact of COVID-19 on the epidemiology of orthopedic trauma surgery. The reasons are to be found in the rationalization of the personnel in favour of emergency departments, ICU and brand new departments used to treat COVID-19 affected patients, and to limit the flow of visitors in the hospital that could be a source of contagion for healthcare staff and patients.
    keywords: covid-19; italy; surgery
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        item: #3193 of 7819
          id: cord-292173-95t89yee
      author: Villani, Federico Alcide
       title: COVID-19 and Dentistry: Prevention in Dental Practice, a Literature Review
        date: 2020-06-26
       words: 4589
      flesch: 43
     summary: In patients with a cured COVID-19 infection, the American Dental Association (ADA) guidelines propose to reschedule dental treatment at least 72 h after the resolution of the symptoms, or 7 days after the appearance of initial symptoms, such as fever controlled without antipyretics and spontaneous improvement of breathing [39] . Further accurate studies have been carried out to demonstrate the importance of oral rinses just before dental treatment; Costa et al., in a study in 2019, highlighted how the use of chlorhexidine at 0.12% and 0.20% alters the amount of bacteria, viruses, and fungi present in the oral biofilm, reducing the risk of cross-contamination due to aerosol [29] .
    keywords: authors; coronavirus; covid-19; dental; health; masks; protection; respirators; review; sars; use
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        item: #3194 of 7819
          id: cord-292180-sjmeyhan
      author: Guzman-Prado, Yuli
       title: Retraction of studies on potential drug therapies for COVID-19: A call for reliability and scientific integrity
        date: 2020-06-30
       words: 550
      flesch: 24
     summary: key: cord-292180-sjmeyhan authors: Guzman-Prado, Yuli title: Retraction of studies on potential drug therapies for COVID-19: A call for reliability and scientific integrity date: 2020-06-30 journal: Am J Cardiol DOI: 10.1016/j.amjcard.2020.06.061 sha: doc_id: 292180 cord_uid: sjmeyhan nan The author of this paper recently discussed the findings on cardiovascular safety of the controversial use of chloroquine (CQ) and hydroxychloroquine (HCQ) for the treatment of COVID-19 reported in observational studies, stressing the need of high quality large randomized controlled trials in order to assess the effectiveness and safety of these drugs and other potential therapies for COVID-19 (1). One of the commented studies (2) , which reported a decrease in the in-hospital survival and an increased frequency of de-novo ventricular arrhythmias with the use of CQ or HCQ, was recently retracted by three of the four authors, causing controversy in the scientific community and raising serious concerns on the reliability of published papers and the transparency and accountability of researchers particularly in the midst of this global health crisis.
    keywords: covid-19; retraction
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        item: #3195 of 7819
          id: cord-292195-k07io2qo
      author: Staib, Andrew
       title: Emergency Medicine’s COVID Future: facing the triple challenge after flattening the curve
        date: 2020-06-02
       words: 1447
      flesch: 43
     summary: In this new normal, Emergency Departments face the triple challenge of: 1) Management of COVID-19 patients EDs will continue to contribute to the management of confirmed COVID cases which are expected to occur as part of low-level community transmission and localized outbreaks and clusters. The COVID-19 Australian National Guidelines mandate immediate placement of potential COVID patients in a single room or physically separated closed area when they arrive at an ED(5).
    keywords: covid-19; emergency; new
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        item: #3196 of 7819
          id: cord-292201-e7k7gn9q
      author: Fodjo, Joseph Nelson Siewe
       title: Mass masking as a way to contain COVID-19 and exit lockdown in low- and middle-income countries
        date: 2020-07-17
       words: 1285
      flesch: 45
     summary: The role of community-wide wearing of face mask for control of coronavirus disease 2019 (COVID-19) epidemic due to SARS-CoV-2 Advice on the use of masks in the context of COVID-19: interim guidance Rational use of face masks in the COVID-19 pandemic. Recent evidence supports a predominantly airborne transmission route for COVID-19, and strongly encourages face mask use in public to prevent inter-human transmission.
    keywords: covid-19; face; masks; use
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        item: #3197 of 7819
          id: cord-292234-8o4kfhe1
      author: Cox, Louis Anthony
       title: Should air pollution health effects assumptions be tested? Fine particulate matter and COVID-19 mortality as an example
        date: 2020-09-02
       words: 8116
      flesch: 29
     summary: Table 2 as evidence that an increase in PM2.5 increases PM2.5 mortality risk would be mistaken In general, the causal conclusions derived by applying conditional independence tests to observational data are as follows: If the null hypothesis of conditional independence between exposure and response (here, PM2.5 and COVID-19 mortality risk) is not rejected (i.e., if there is no arrow between them in a BN, and if PM2.5 is not J o u r n a l P r e -p r o o f Journal Pre-proof identified as a significant predictor of COVID-19 mortality risk after conditioning on other variables such as winter temperatures in a CART tree), then these tests provide no evidence that exposure is a cause of response, in the rather permissive sense just discussed.
    keywords: causal; covid-19; data; evidence; model; mortality; pm2.5; regression; risk; variables
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        item: #3198 of 7819
          id: cord-292235-ckm89lnm
      author: Kummer, Benjamin R.
       title: History of Stroke Is Independently Associated With In-Hospital Death in Patients With COVID-19
        date: 2020-07-31
       words: 1605
      flesch: 41
     summary: Compared with patients without history of stroke, patients with history of stroke were significantly more likely to die during their hospitalization (48.6% versus 31.7%, P<0.001; In this descriptive, observational study of hospitalized patients with COVID-19, we found that history of stroke was independently associated with in-hospital death. We found that history of stroke was associated with in-hospital death among hospitalized patients with COVID-19.
    keywords: death; history; patients; stroke
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        item: #3199 of 7819
          id: cord-292260-4zw08scs
      author: Mohamed-Hussein, A.
       title: Post-COVID-19 Functional Status: Relation to age, smoking, hospitalization and comorbidities
        date: 2020-09-01
       words: 2373
      flesch: 47
     summary: https://doi.org/10.1101/2020.08.26.20182618 doi: medRxiv preprint One-year outcomes and health care utilization in survivors of severe acute respiratory syndrome The long-term impact of severe acute respiratory syndrome on pulmonary function, exercise capacity and health status Fatigue symptoms during the first year following ARDS Measuring functional limitations after venous thrombo embolism: a call to action Measuring functional limitations after venous thromboembolism: optimization of the post-VTE functional status (PVFS) scale Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Incidence of thrombotic complications in critically ill ICU patients with COVID-19 The Post-COVID-19 Functional Status scale: a tool to measure functional status over time after COVID-19 Features of 20 133 UK patients in hospital with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan The new challenge of geriatrics: saving frail older people from the SARS-CoV-2 pandemic infection It is recommended that the functional state could have predictive value for COVID-19 patients, as compromised physical activity was independently concomitant with worst consequences in hospitalized cases with community-acquired pneumonia, according to a recent prospective study (24).
    keywords: cases; covid-19; medrxiv; patients; preprint
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        item: #3200 of 7819
          id: cord-292273-xu9pb9ul
      author: Guillamet, C. V.
       title: TOWARD A COVID-19 SCORE-RISK ASSESSMENTS AND REGISTRY
        date: 2020-04-20
       words: 3742
      flesch: 47
     summary: A voluntary registry option reporting subsequent patient outcomes will enable us to further validate and make improvements in the score and our understanding of COVID-19. US and European colleagues treating COVID-19 patients confirm that many deaths are from primary respiratory, not multiple system, failure 10 .
    keywords: covid-19; hospital; hours; license; mortality; patients; preprint; tacs
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        item: #3201 of 7819
          id: cord-292274-upwn9o2m
      author: Ghaffari, Abdi
       title: COVID-19 Serological Tests: How Well Do They Actually Perform?
        date: 2020-07-04
       words: 4663
      flesch: 39
     summary: In humans, three types of antibodies or immunoglobulins have been the target of COVID-19 serological tests: IgM, IgG, and IgA. In humans, three types of antibodies or immunoglobulins have been the target of COVID-19 serological tests: IgM, IgG, and IgA.
    keywords: antibodies; antibody; cov-2; covid-19; igg; igm; sars; tests
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        item: #3202 of 7819
          id: cord-292295-57copxdc
      author: Grigoletto, Isis
       title: Recovery after COVID-19: The potential role of pulmonary rehabilitation
        date: 2020-07-19
       words: 959
      flesch: 32
     summary: World Health Organization Clinical characteristics of coronavirus disease 2019 in China The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak ----an update on the status The 1-year impact of severe acute respiratory syndrome on pulmonary function, exercise capacity, and quality of life in a cohort of survivors Impact of severe acute respiratory syndrome (SARS) on pulmonary function, functional capacity and quality of life in a cohort of survivors ICU-acquired weakness and recovery from critical illness SARS CoV-2 (COVID-19): lessons to be learned by Brazilian Physical Therapists Physiotherapy management for COVID-19 in the acute hospital setting: clinical practice recommendations Report of an ad-hoc international task force on early and short-term rehabilitative interventions in COVID-19 survivors Differences in content and organisational aspects of pulmonary rehabilitation programmes Outpatient pulmonary rehabilitation following acute exacerbations of COPD Effect of early pulmonary rehabilitation on health care utilization and health status in patients hospitalized with acute exacerbations of COPD Australian and New Zealand pulmonary rehabilitation guidelines Pulmonary rehabilitation exercise prescription in chronic obstructive pulmonary disease: Review of selected guidelines: an official statement from the american association of cardiovascular and pulmonary Q7 rehabilitation An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation Isis Grigoletto a, * , Vinicius Cavalheri b Ercy Mara Cipulo Ramos a a Department of Physical Therapy, Postgraduate Program in Physical Therapy, Faculty of Science and Technology The benefits of pulmonary rehabilitation are well known and the existing programs could be used as one of the rehabilitation referral pathways for COVID-19 survivors who present with symptoms and/or impairments in physical function.
    keywords: covid-19; function; pulmonary; rehabilitation
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        item: #3203 of 7819
          id: cord-292296-nocmabcg
      author: Shang, L.
       title: Fangcang shelter hospitals in COVID-19 pandemic: the practice and its significance
        date: 2020-05-01
       words: 1576
      flesch: 41
     summary: In this issue of Clinical Microbiology and Infection, Wang et al. described the work flow of Fangcang shelter hospitals and reported the clinical characteristics of COVID-19 patients in Dongxihu Fangcang shelter hospital, one of the largest Fangcang shelter hospitals in Wuhan [9] . key: cord-292296-nocmabcg authors: Shang, L.; Xu, J.; Cao, B. title: Fangcang shelter hospitals in COVID-19 pandemic: the practice and its significance date: 2020-05-01 journal: Clin Microbiol Infect DOI: 10.1016/j.cmi.2020.04.038 sha: doc_id: 292296 cord_uid: nocmabcg nan Coronavirus disease 2019 (COVID-19), an emerging respiratory infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been spreading across the world rapidly and claiming tens of thousands of lives.
    keywords: covid-19; fangcang; patients; shelter
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        item: #3204 of 7819
          id: cord-292312-cwrqorn1
      author: Sales, M. J. T.
       title: Fernando de Noronha: how an island controlled the community transmission of COVID-19 in Brazil
        date: 2020-10-27
       words: 4333
      flesch: 52
     summary: This is especially critical in Brazil, until recently, the country with the second largest number of COVID-19 cases in the world 2 . The findings were compared to national estimates and with experience on other islands of similar size.
    keywords: brazil; cases; covid-19; fna; health; island; measures; pcr; preprint; study
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        item: #3205 of 7819
          id: cord-292331-j3dk6h68
      author: Muniz, Bernardo Carvalho
       title: COVID-19 - Computed tomography findings in two patients in Petrópolis, Rio de Janeiro, Brazil
        date: 2020-04-22
       words: 451
      flesch: 52
     summary: Universidade Federal do Rio de Janeiro, Departamento de Radiologia, Rio de Janeiro, RJ, Brasil. Patients were considered suspicious for COVID-19, and collection of material to conduct the SARS-CoV-2 research by polymerase chain reaction (PCR), was performed.
    keywords: covid-19; patients
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        item: #3206 of 7819
          id: cord-292341-uo54ghf3
      author: Cocconcelli, Elisabetta
       title: Clinical Features and Chest Imaging as Predictors of Intensity of Care in Patients with COVID-19
        date: 2020-09-16
       words: 5198
      flesch: 44
     summary: All these findings emphasize the importance of past medical history and comorbidities in the disease course of COVID-19 patients, as they may predispose to worse outcome and higher intensity of care. Pevious reports on CXR findings in COVID-19 patients focused on the distribution and type of lung abnormalities.
    keywords: admission; care; covid-19; cxr; global; lus; patients; score
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        item: #3207 of 7819
          id: cord-292345-zc209dfx
      author: Carroll, Elizabeth
       title: Catastrophic Intracranial Hemorrhage in Two Critically Ill Patients with COVID-19
        date: 2020-05-26
       words: 1583
      flesch: 45
     summary: However, brain autopsies from other patients with COVID-19 have reportedly demonstrated hyperemic and edematous parenchyma [2] . Although it has been noted that COVID-19 may increase risk for acute cerebrovascular events, including both ischemic and hemorrhagic stroke [2] , to our knowledge, this is the first report of patients with COVID-19 who had catastrophic intracranial hemorrhages.
    keywords: anticoagulation; covid-19; patients
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        item: #3208 of 7819
          id: cord-292347-d7xq7x5g
      author: Carter, Linda J.
       title: Assay Techniques and Test Development for COVID-19 Diagnosis
        date: 2020-04-30
       words: 3437
      flesch: 38
     summary: This type of testing requires cell culture facilities, 470 and in the case of SARS coronavirus, Biosafety Level 3 (BSL3) 471 laboratories. These tests have a huge potential for the epide-397 miology of COVID-19, 32,42−45 but test results can be impacted by 398 at least three situations: (1) a subset of subjects with a positive 399 result from molecular genetic assays for SARS-CoV-2 infection 400 are seronegative due to the lag in antibody production following 401 infection, (2) the subjects may be seropositive yet negative for 402 molecular genetic assay results reflecting clearance of an earlier, 403 milder infection, and (3) limitation in sensitivity and specificity of 404 the assays.
    keywords: antibodies; assays; coronavirus; cov-2; covid-19; detection; infection; rna; sars; test; testing
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        item: #3209 of 7819
          id: cord-292350-cmrtg91a
      author: Mondal, Samhati
       title: Thromboembolic disease in COVID-19 patients: A brief narrative review
        date: 2020-09-14
       words: 4006
      flesch: 20
     summary: key: cord-292350-cmrtg91a authors: Mondal, Samhati; Quintili, Ashley L.; Karamchandani, Kunal; Bose, Somnath title: Thromboembolic disease in COVID-19 patients: A brief narrative review date: 2020-09-14 journal: J Intensive Care DOI: 10.1186/s40560-020-00483-y sha: doc_id: 292350 cord_uid: cmrtg91a Corona virus 2 (SARS-CoV2/ Severe Acute Respiratory Syndrome Corona Virus 2) infection has emerged as a global health crisis. Table 1 & 2 summarize the various thrombotic complications noted in COVID-19 patients as published as of June 6 th , 2020 obtained by a literature search on PubMed and EMBASE using combinations of the following MeSH terms: COVID-19, SARS-COV2, novel corona virus, thrombosis, thromboembolic complications, pulmonary embolism.
    keywords: acute; anticoagulation; complications; covid-19; disease; patients; pulmonary; risk; thrombosis; venous
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        item: #3210 of 7819
          id: cord-292372-kn27ghlv
      author: de Chaisemartin, Clément
       title: BCG vaccination in infancy does not protect against COVID-19. Evidence from a natural experiment in Sweden
        date: 2020-08-23
       words: 2820
      flesch: 50
     summary: key: cord-292372-kn27ghlv authors: de Chaisemartin, Clément; de Chaisemartin, Luc title: BCG vaccination in infancy does not protect against COVID-19. We used regression discontinuity to assess the effect of BCG vaccination on Covid-19 related outcomes.
    keywords: bcg; cases; covid-19; effect; vaccination
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        item: #3211 of 7819
          id: cord-292378-mz3cvc0p
      author: Bone, A. E.
       title: Changing patterns of mortality during the COVID-19 pandemic: population-based modelling to understand palliative care implications
        date: 2020-06-09
       words: 3916
      flesch: 54
     summary: We observe a 77% increase in home deaths between weeks 11 (n=2,725) and 17 (n=4834), while care home deaths increased by 220% during the same period (week 11 n=2,471, week 17 n= 7,911). We described the following mortality categories by age, gender and place of death: 1) baseline deaths (deaths that would typically occur in a given period) 2) COVID-19 deaths 3) additional deaths not directly attributed to COVID-19.
    keywords: care; covid-19; deaths; license; medrxiv; preprint
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        item: #3212 of 7819
          id: cord-292386-hfbgigj6
      author: Borges, Lysandro Pinto
       title: Seroprevalence of SARS-CoV-2 IgM and IgG antibodies in an asymptomatic population in Sergipe, Brazil
        date: 2020-10-06
       words: 3902
      flesch: 42
     summary: Nonetheless, serological testing has become an extremely helpful tool in epidemiology, since it is able to detect recent and past infections, including asymptomatic and recovered cases, providing better information regarding disease prevalence in a population. Estimating IgG prevalence is extremely important in terms of returning to work, although there is no evidence supporting whether this antibody may function as an immunity passport (31) .
    keywords: antibodies; cases; cov-2; covid-19; igm; individuals; population; prevalence; sars; sergipe; study
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        item: #3213 of 7819
          id: cord-292396-8w06oc5i
      author: Leger, Thomas
       title: Low-dose chest CT for diagnosing and assessing the extent of lung involvement of SARS-CoV-2 pneumonia using a semi quantitative score
        date: 2020-11-03
       words: 3388
      flesch: 52
     summary: In particular, lymph nodes and pleural effusion are highly frequent in severe patients. This type of CT score was first described in 2004 for severe acute respiratory syndrome (SARS).
    keywords: covid-19; involvement; ldct; lung; news; patients; score
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        item: #3214 of 7819
          id: cord-292407-7xjw1lsb
      author: Gil, Holly
       title: 48-year-old with Coronavirus Disease 2019
        date: 2020-05-07
       words: 654
      flesch: 51
     summary: Although not diagnostic, imaging can suggest the presence of COVID-19 disease, and the American College of Radiology has adopted standardized language to reduce reporting variability. COVID-19) and the virus that causes it -2019)-and-the-virus-that-causesit An update on COVID-19 for the radiologist: A British Society of Thoracic Imaging statement Frequency and distribution of chest radiographic findings in COVID-19 positive patients Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT ACR recommendations for the use of chest radiography and computer tomography (CT) for suspected COVID-19 infection Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection Severe acute respiratory syndrome-related coronavirus: the species and its viruses -a statement of the Coronavirus Study Group World Health Organization.
    keywords: chest; covid-19
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        item: #3215 of 7819
          id: cord-292417-hauq93v2
      author: Xue, Mingshan
       title: Predictive effects of IgA and IgG combination to assess pulmonary exudation progression in COVID‐19 patients
        date: 2020-08-17
       words: 2586
      flesch: 47
     summary: Because of the limitation of physical condition in severe patients, their changes of lung condition were examined with bedside chest PA&LAT (posteroanterior oblique and lateral views). In this study, chest PA & LAT was mainly used on severe patients, while the HRCT was still used on patients with milder clinical presentation.
    keywords: covid-19; days; iga; igg; lung; patients
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        item: #3216 of 7819
          id: cord-292423-jupcit75
      author: Narkhede, Rohan R.
       title: Recognition of Natural Products as Potential Inhibitors of COVID-19 Main Protease (Mpro): In-Silico Evidences
        date: 2020-06-17
       words: 2713
      flesch: 47
     summary: The docking of the phytoconstituents in COVID-19 main protease was subsequently visualized for their binding in the pocket of the protein. Since the native inhibitor (N2) accommodated in the crystal structure of COVID-19 main protease, it allowed the natural products to bind in the active sites of the protein.
    keywords: activity; covid-19; docking; drug; potential; products; protease
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        item: #3217 of 7819
          id: cord-292462-zbjig3pt
      author: Backhaus, Andreas
       title: Common Pitfalls in the Interpretation of COVID-19 Data and Statistics
        date: 2020-06-07
       words: 3167
      flesch: 52
     summary: If the difference was larger than the COVID-19 death count, it would suggest an undercounting of COVID-19 deaths, as the reported COVID-19 death count cannot fully account for the observed excess mortality. Here's how to kick their tires Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship Total confi rmed COVID-19 deaths Estimating the infection and case fatality ratio for coronavirus disease (COVID-19) using ageadjusted data from the outbreak on the Diamond Princess cruise ship Preliminary statistics on deaths OpenSAFELY: factors associated with COV-ID-19
    keywords: cases; confi; covid-19; data; death; rmed
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        item: #3218 of 7819
          id: cord-292474-dmgd99d6
      author: Berardi, Giammauro
       title: Continuing our work: transplant surgery and surgical oncology in a tertiary referral COVID-19 center
        date: 2020-06-04
       words: 4612
      flesch: 38
     summary: As a further issue, it has already been shown that cancer patients are more susceptible to COVID-19 infections: 1% of COVID-19 patients in China had a history of cancer as compared to 0.29% among normal Chinese population [2] . Italy was one of the first western countries diagnosing COVID-19 patients in late January and was certainly the one suffering the most by the sudden outbreak of the disease.
    keywords: cancer; cases; covid-19; icu; outbreak; pandemic; patients; surgery; transplantations
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        item: #3219 of 7819
          id: cord-292490-djp9onk5
      author: Verma, V. R.
       title: Projecting Demand-Supply Gap of Hospital Capacity in India in the face of COVID-19 pandemic using Age-Structured Deterministic SEIR model
        date: 2020-05-19
       words: 5734
      flesch: 41
     summary: Further, we computed the daily turnover of each of these resources which was then adjusted for proportion of cases requiring mild, severe and critical care to arrive at maximum number of COVID-19 cases manageable by health care system of India. National Health Profile Directorate General of Health Services M of H and FW Estimating the maximum capacity of COVID-19 cases manageable per day given a health care system's constrained resources UTILIZATION PATTERN AND FINANCING OF PUBLIC HOSPITALS:
    keywords: beds; capacity; cases; covid-19; demand; health; india; lockdown; preprint; testing
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        item: #3220 of 7819
          id: cord-292493-lx7zfgoi
      author: Firstenberg, Michael S.
       title: Isolation protocol for a COVID-2019 patient requiring emergent surgical intervention: case presentation
        date: 2020-04-19
       words: 2355
      flesch: 47
     summary: The family did not visit him during his hospitalization due to the concern of COVID-2019 and subsequent anticipated need for self-quarantine, which is now hospital policy as well to not have visitors for suspect or confirmed COVID-2019 patients. Nevertheless, as the number of positive cases continue to growwith the associated morbidity and mortality, it is critical to control further spread via implementation and strict compliance with isolation precautions, as healthcare workers and other patients are at significant risk for exposure [2] .
    keywords: blood; covid-2019; icu; patient; room; team
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        item: #3221 of 7819
          id: cord-292501-2jv7xkfn
      author: Jiang, Saiping
       title: Liver Injury in Critically Ill and Non-critically Ill COVID-19 Patients: A Multicenter, Retrospective, Observational Study
        date: 2020-06-23
       words: 4411
      flesch: 41
     summary: According to the latest epidemiological studies, ∼16-53% of patients with COVID-19 experienced different degrees of liver injury (4, (7) (8) (9) (10) (11) (12) (13) , and some patients have developed severe liver injury. Although some studies have reported the incidence of liver injury in patients with COVID-19 (8, 14, 15) , there are limited data describing the course of liver injury occurrence, such as liver injury onset, progression, and recovery, during an entire hospitalization period, particularly in patients with different disease severity.
    keywords: arbidol; clinical; covid-19; injury; liver; liver injury; patients; study
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        item: #3222 of 7819
          id: cord-292502-m76rne1l
      author: Cheema, S.
       title: The COVID-19 pandemic: the public health reality
        date: 2020-09-22
       words: 2731
      flesch: 44
     summary: Moving forward and with pandemics likely to re-occur, we call for health decisions to be made on the basis of science and public health evidence. The study points out that 40% use cleaning agents or disinfectants in an unsafe manner that presents health risks.
    keywords: covid-19; deaths; disease; health; mortality; pandemic; public
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        item: #3223 of 7819
          id: cord-292508-unoeicq0
      author: Teshome, Abinet
       title: Generalized Anxiety Disorder and Its Associated Factors Among Health Care Workers Fighting COVID-19 in Southern Ethiopia
        date: 2020-11-05
       words: 4557
      flesch: 44
     summary: Protecting the mental health of healthcare workers during the COVID-19 emergency Mental symptoms in different health professionals during the SARS attack: A follow-up study The psychological impact of the SARS epidemic on hospital employees in China: exposure, risk perception, and altruistic acceptance of risk The prevalence and influencing factors in anxiety in medical workers fighting COVID-19 in China: a cross-sectional survey Mental health and psychosocial problems of medical health workers during the COVID-19 Epidemic in China Psychological impact of the COVID-19 pandemic on health care workers in Singapore Impact of severe acute respiratory syndrome on anxiety levels of front-line health care workers Ethiopian monitor A brief measure for assessing generalized anxiety disorder Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019 Depression, anxiety, stress levels of physicians and associated factors in covid-19 pandemics Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis Prevalence and influencing factors of anxiety and depression symptoms in the first-line medical staff fighting against COVID-19 in Gansu A multinational, multicentre study on the psychological outcomes and associated physical symptoms amongst healthcare workers during COVID-19 outbreak Psychological impact of the COVID-19 pandemic on health care workers in Singapore Covid-19 infection in Italy: an occupational injury The findings of the current study suggest immediate psychological intervention for health care workers in the study area is vital.
    keywords: anxiety; care; covid-19; data; disorder; hcws; health; study; workers
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        item: #3224 of 7819
          id: cord-292519-dod8k0xa
      author: Goldstein, Mark R
       title: Does apolipoprotein E genotype predict COVID-19 severity?
        date: 2020-04-27
       words: 698
      flesch: 37
     summary: A major driving force for the development of ARDS is a cytokine storm, which is an uncontrolled release of pro-inflammatory cytokines and chemokines by immune effector cells in response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [2] . It has been shown that possessing one or two copies of apoE4, versus two copies of apoE3, is associated with an augmented in vivo innate immune response to an intravenous lipopolysaccharide challenge, as manifested by higher hyperthermia and cytokine levels [6] .
    keywords: apoe; disease
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        item: #3225 of 7819
          id: cord-292537-9ra4r6v6
      author: Liu, Fenglin
       title: Predicting and analyzing the COVID-19 epidemic in China: Based on SEIRD, LSTM and GWR models
        date: 2020-08-27
       words: 5675
      flesch: 47
     summary: Among them, the number of confirmed cases was the mostly used and reflected the severity of COVID-19 epidemic. The average percent error of LSTM model predictions for the four selected provinces and cities was within ±1.0% on February 14 th (Table 5) .
    keywords: cases; china; coronavirus; covid-19; data; epidemic; model; number; rate; study; wuhan
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        item: #3226 of 7819
          id: cord-292539-i10k2ld4
      author: Majidi, Hadi
       title: High-resolution computed tomography finding in 552 patients with symptomatic COVID-19: first report from north of Iran
        date: 2020-07-13
       words: 2238
      flesch: 51
     summary: According to several studies that examined the imaging findings of COVID-19 patients, 69 to 89% of the patients had positive chest CT findings This cross-sectional study was performed on COVID-19 patients referred to Medical Imaging Centers of Sari, Mazandaran, Iran, on March 2020 for computed tomography (CT) scan.
    keywords: coronavirus; covid-19; patients; study
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        item: #3227 of 7819
          id: cord-292544-m7jyydf1
      author: Grau-Pujol, Berta
       title: Pre-exposure prophylaxis with hydroxychloroquine for high-risk healthcare workers during the COVID-19 pandemic: A structured summary of a study protocol for a multicentre, double-blind randomized controlled trial
        date: 2020-07-29
       words: 4577
      flesch: 44
     summary: Study participant flowchart The occurrence of an AE or SAE may come to the attention of study personnel during study visits and interviews of a study participant presenting for medical care, or upon review by the study monitor.
    keywords: cov-2; covid-19; group; healthcare; hydroxychloroquine; prep; sars; study; workers
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        item: #3228 of 7819
          id: cord-292546-un0blb3w
      author: Dandachi, Dima
       title: Characteristics, Comorbidities, and Outcomes in a Multicenter Registry of Patients with HIV and Coronavirus Disease-19
        date: 2020-09-09
       words: 3441
      flesch: 50
     summary: Infection Clinical features and outcomes of HIV patients with coronavirus disease 2019 Outcomes among HIV-positive patients hospitalized with COVID-19 Covid-19 and People with HIV Infection: Outcomes for Hospitalized Patients Clinical characteristics, comorbidities and outcomes among persons with HIV hospitalized with coronavirus disease Description of COVID-19 in HIV-infected individuals: a single-centre, prospective cohort. Ongoing research aims to determine the impact of structural racism in COVID-19 outcomes.
    keywords: covid-19; hiv; outcomes; patients
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        item: #3229 of 7819
          id: cord-292551-n3gzgn6w
      author: Pavarini, Gabriela
       title: Debate: Promoting capabilities for young people's agency in the COVID‐19 outbreak
        date: 2020-08-13
       words: 1266
      flesch: 37
     summary: Young people in Kenya have initiated 'Mutual Aid Kenya' to help vulnerable members of their local communities handle the outbreak, and young people in Cameroon have started a home production of hand sanitisers to be distributed to the population cost-free (Wickramanayake, 2020) . In addition to active participation in research, it is also important to support young people in the design and delivery of peer-to-peer education and mental health interventions.
    keywords: covid-19; health; people; young
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        item: #3230 of 7819
          id: cord-292561-iy06b9h9
      author: Miesbach, Wolfgang
       title: COVID-19: Coagulopathy, Risk of Thrombosis, and the Rationale for Anticoagulation
        date: 2020-07-17
       words: 4900
      flesch: 40
     summary: These laboratory changes are consistent with previous studies which showed that hypoalbuminemia, lymphopenia, and C-reactive protein 4 mg/dL were the predictive factors for the progression of pneumonia to respiratory failure in MERS-CoV-infected patients and that elevated lactate dehydrogenase (LDH) levels were associated with hospital-acquired infection with SARS-CoV. 16 Similar to SARS and MERS, there is a link between inflammation and severe organ damage in COVID-19 patients. 32 Coagulopathy has been described in studies that document clinical and laboratory changes in COVID-19 patients in up to 50% of those with severe manifestations.
    keywords: acute; coagulopathy; covid-19; dimer; levels; patients; risk; sars; syndrome; thrombosis
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        item: #3231 of 7819
          id: cord-292611-5os99sve
      author: Lopes, Renato D.
       title: Anticoagulation in COVID-19: It Is Time for High-Quality Evidence
        date: 2020-10-20
       words: 221
      flesch: -20
     summary: Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Pulmonary embolism in patients with COVID-19: awareness of an increased prevalence Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19 Endothelial cell infection and endotheliitis in COVID-19 Evidence-based practical guidance for the antithrombotic management in patients with coronavirus disease (COVID-19) in 2020 COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up: JACC State-ofthe-Art Review Anticoagulation, bleeding, mortality, and pathology in hospitalized patients with COVID-19 Randomized trials versus common sense and clinical observation: JACC Review Topic of the Week Meta-analysis: anticoagulant prophylaxis to prevent symptomatic venous thromboembolism in hospitalized medical patients Heparin thromboprophylaxis in medical-surgical critically ill patients: a systematic review and meta-analysis of randomized trials American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients COVID-19, randomized controlled trials JACC [Figure: see text] There are many challenges to conducting randomized controlled trials, especially in the face of a pandemic, but they are necessary to determine whether and how treatments affect outcomes.
    keywords: covid-19
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        item: #3232 of 7819
          id: cord-292620-t8ocqm6g
      author: Somani, S.
       title: Characterization of Patients Who Return to Hospital Following Discharge from Hospitalization For COVID-19
        date: 2020-05-22
       words: 2773
      flesch: 43
     summary: Finally, returning patients had shorter LOS on index hospitalization with notably a lower frequency of ICU care and inpatient anticoagulation. key: cord-292620-t8ocqm6g authors: Somani, S.; Richter, F.; Fuster, V.; De Freitas, J.; Naik, N.; Sigel, K.; Mount Sinai Covid Informatics Center,; Boettinger, E. P.; Levin, M. A.; Fayad, Z.; Just, A. C.; Charney, A.; Zhao, S.; Glicksberg, B. S.; Lala, A.; Nadkarni, G. title: Characterization of Patients Who Return to Hospital Following Discharge from Hospitalization For COVID-19 date: 2020-05-22 journal: medRxiv : the preprint server for health sciences DOI: 10.1101/2020.05.17.20104604 sha: doc_id:
    keywords: covid-19; discharge; hospital; medrxiv; patients; preprint; return
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        item: #3233 of 7819
          id: cord-292629-5kh46tks
      author: Divala, Titus
       title: Africa faces difficult choices in responding to COVID-19
        date: 2020-05-12
       words: 475
      flesch: 45
     summary: We estimate that in the UK, having COVID-19 confers risk of death equivalent to approximately 12 months of background mortality risk, averaged across all age groups. Without a context-specific, ethical approach to physical distancing, unintended harms from stringent lockdown could pose more harm than the direct effects of COVID-19 itself.
    keywords: covid-19; lockdown
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        item: #3234 of 7819
          id: cord-292666-6xer2cty
      author: Mansab, F.
       title: Patient-Led COVID-19 Triage Systems and Case Fatality Rates: A Comparative Study Between Singapore, Japan, Norway, the USA and the UK.
        date: 2020-05-05
       words: 2725
      flesch: 58
     summary: Methods: A simulation study was conducted on current, nationwide, patient-led triage systems from three countries with low case fatality rates (Singapore, Norway and Japan) and two countries with high case fatality rates (the USA and the UK). The many estimates of the COVID-19 case fatality rate Lower mortality of COVID-19 by early recognition and intervention: experience from Jiangsu Province Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan Optimizing triage and hospitalization in adult general medical emergency patients: the triage project Role of primary care in the COVID-19 response Algorithm for COVID-19 triage and referral : patient triage and referral for resource-limited settings during community transmission Interim Treatment Guidelines for COVID-19 COVID-19 in Singapore-Current Experience: Critical Global Issues That Require Attention and Action Singapore COVID-19 Symptom Checker Triage: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis Severely Ill People Should Seek Medical Care Empiric antibiotic treatment reduces mortality in severe sepsis and septic shock from the first hour: results from a guideline-based performance improvement program
    keywords: covid-19; patient; preprint; triage
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        item: #3235 of 7819
          id: cord-292698-w7wrwj95
      author: Rothstein, Rachel
       title: School Nurses on the Front Lines of Healthcare: The Approach to Maintaining Student Health and Wellness During COVID-19 School Closures
        date: 2020-06-25
       words: 3057
      flesch: 47
     summary: While the term social distancing is likely new to many, the concept of school closures as a tool for reducing spread of infectious diseases originated long before the COVID-19 pandemic. While the current durations of school closures exceed those of other infectious disease outbreaks in recent history, consistent are the challenges to maintaining student health and wellness in light of closures.
    keywords: care; children; closures; covid-19; health; school; table; website
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        item: #3236 of 7819
          id: cord-292721-954nxptr
      author: Grey, Ian
       title: The Role of Perceived Social Support on Depression and Sleep during the COVID-19 Pandemic
        date: 2020-09-18
       words: 4653
      flesch: 39
     summary: Firstly, perceived social support measures are designed to assess individual perceptions concerning the general availability and adequacy of support and/or global satisfaction with support provided whereas measures of received support targets the specific supportive behaviours that are provided to individuals by their social support networks (Eagle et al., 2019) . key: cord-292721-954nxptr authors: Grey, Ian; Arora, Teresa; Thomas, Justin; Saneh, Ahmad; Tomhe, Pia; Habib, Rudy Abi title: The Role of Perceived Social Support on Depression and Sleep during the COVID-19 Pandemic date: 2020-09-18 journal: Psychiatry Res DOI: 10.1016/j.psychres.2020.113452 sha: doc_id: 292721 cord_uid: 954nxptr The aim of the present study was to examine the role of perceived social support pertaining to a range of psychological health outcomes amongst individuals undergoing social isolation and social distancing during COVID-19.
    keywords: anxiety; depression; health; quality; sleep; social; support
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        item: #3237 of 7819
          id: cord-292751-tk1oggi9
      author: Hosseini, Elahe Seyed
       title: The novel coronavirus Disease-2019 (COVID-19): Mechanism of action, detection and recent therapeutic strategies
        date: 2020-09-24
       words: 3817
      flesch: 42
     summary: The Lancet infectious diseases Anti-malaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal model Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Coronaviruses-drug discovery and therapeutic options Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections Comparative effectiveness of combined favipiravir and oseltamivir therapy versus oseltamivir monotherapy in critically ill patients with influenza virus infection The Novel Chinese Coronavirus (2019-nCoV) Infections: challenges for fighting the storm Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses A randomized, controlled trial of Ebola virus disease therapeutics Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease Therapeutic options for the 2019 novel coronavirus (2019-nCoV). MedRxiv Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis Sex-based differences in susceptibility to severe acute respiratory syndrome coronavirus infection Sexual dimorphism in innate immunity An ultrasensitive, rapid, and portable coronavirus SARS-CoV-2 sequence detection method based on CRISPR-Cas12.
    keywords: 2019; coronavirus; cov-2; covid-19; infection; ncov; novel; patients; pneumonia; rna; sars
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        item: #3238 of 7819
          id: cord-292792-goh51sya
      author: Pascual Gómez, Natalia F.
       title: Potenciales biomarcadores predictores de mortalidad en pacientes COVID-19 en el Servicio de Urgencias
        date: 2020-07-13
       words: 2972
      flesch: 45
     summary: Un nuevo coronavirus conocido como severe acute respiratory síndrome coronavirus 2 (SARS-CoV-2), causante del cuadro clínico COVID-19 ha sido el responsable de la declaración de emergencia el pasado 30 de enero de 2020 Respecto a los marcadores séricos que puedan orientarnos hacia la estratificación de la gravedad, y el pronóstico de COVID-19, se han estudiado numerosos parámetros, desde los indicadores de la función de filtración glomerular (cistatina C, creatinina y urea), la bilirrubina directa, colesterol y LDH
    keywords: como; con; covid-19; del; días; ic95; las; los; mortalidad; pacientes; para; por; que; riesgo; score
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        item: #3239 of 7819
          id: cord-292795-yc613g96
      author: Hakeem, Abdul Rahman
       title: Awareness and concerns among adult Liver Transplant recipients in the current pandemic caused by novel coronavirus (COVID-19): Strategies to safeguard a high-risk population
        date: 2020-06-11
       words: 3868
      flesch: 48
     summary: Data on liver transplant recipients infected with SARS-CoV-2 is still limited to case reports and small series (4) (5) (6) (7) (8) . Our survey has demonstrated that liver transplant recipients have reasonable knowledge about the COVID-19 pandemic and most are aware of their high-risk status.
    keywords: concerns; covid-19; liver; patients; recipients; risk; survey; transplant
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        item: #3240 of 7819
          id: cord-292826-lus0tqmi
      author: Joseph, Tony
       title: Trauma care in a low-COVID pandemic environment: A new normal
        date: 2020-06-12
       words: 1268
      flesch: 37
     summary: There will also need to be a re-evaluation of the way that trauma care is delivered with careful consideration of the indication for any trauma -related procedure from intubation to acute surgical care. The insidious nature of early COVID infection, compromised cognition and the unreliability of a subset of trauma patients all result in a significant proportion needing to be initially treated as if they were infected.
    keywords: care; pandemic; patients; trauma
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        item: #3241 of 7819
          id: cord-292835-zzc1a7id
      author: Otoom, Mwaffaq
       title: An IoT-based Framework for Early Identification and Monitoring of COVID-19 Cases
        date: 2020-08-15
       words: 5261
      flesch: 54
     summary: Maghdid proposed the use of sensors available on smartphones to collect health data, such as temperature [16] . Hamidi studied authentication of IoT smart health data to ensure privacy and security of health information.
    keywords: algorithms; cases; covid-19; data; health; instance; iot; learning; machine; time
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        item: #3242 of 7819
          id: cord-292878-wbfi0v2x
      author: Merchant, Reshma A.
       title: The Role of a Geriatrician has Become Even More Important in an Academic Institution during COVID-19
        date: 2020-05-13
       words: 1158
      flesch: 42
     summary: Singapore is filled with high-rise housing with void decks on the ground floor built by the Housing Development Board (HDB), which used to be a meeting place for many older adults before the circuit breaker. While a lot of the resources are being channelled to manage the increasing numbers of COVID-19 patients, frail older adults with multimorbidity continue to be admitted with very complex needs.
    keywords: adults; covid-19; geriatricians; patients
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        item: #3243 of 7819
          id: cord-292880-zegtr19k
      author: Hu, Fuying
       title: Corticosteroid, oseltamivir and delayed admission are independent risk factors for prolonged viral shedding in patients with Coronavirus Disease 2019
        date: 2020-08-13
       words: 3795
      flesch: 47
     summary: On the one hand, evidence suggested that corticosteroid might reduce the risk of death in patients with COVID-19 who developed acute respiratory distress syndrome (ARDS) during hospitalization, 4 but on the other hand, corticosteroid was associated with prolonged viral shedding in mild patients, leading to prolonged hospitalization and increased consumption of medical resources. Although proved effective in patients who developed ARDS during hospitalization, corticosteroid should be initiated with caution, especially in mild patients with COVID-19.
    keywords: corticosteroid; covid-19; patients; sars; shedding; study
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        item: #3244 of 7819
          id: cord-292892-6gwnhkn4
      author: Liu, Bingwen
       title: Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?
        date: 2020-04-10
       words: 2720
      flesch: 17
     summary: Lancet Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Diagnostic Utility of Clinical Laboratory Data Determinations for Patients with the Severe COVID-19 Inhibition of NF-kappaB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis Coronavirus envelope protein: current knowledge FDA Approval Summary: Tocilizumab for Treatment of Chimeric Antigen Receptor T Cell-Induced Severe or Life-Threatening Cytokine Release Syndrome Cytokine release syndrome Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial New therapeutic opportunities for COVID-19 patients with Tocilizumab: Possible correlation of interleukin-6 receptor inhibitors with osteonecrosis of the jaws Cytotoxic therapy for severe avian influenza A (H5N1) infection COVID-19: consider cytokine storm syndromes and immunosuppression The management of COVID-19 (the sixth edition) Polybacterial stimulation suggests discrete IL-6/IL-6R signaling in human fetal membranes: Potential implications on IL-6 bioactivity Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury Clinical Features of 69 Cases with Coronavirus Disease Origin and evolution of pathogenic coronaviruses A pneumonia outbreak associated with a new coronavirus of probable bat origin Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center's observational study Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome An interferon-gamma-related cytokine storm in SARS patients Tocilizumab as an Adjuvant Therapy for Hemophagocytic Lymphohistiocytosis Associated With Visceral Leishmaniasis Tocilizumab for the treatment of chimeric antigen receptor T cell-induced cytokine release syndrome Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patients CAR T cell-induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade Safe usage of anakinra and dexamethasone to treat refractory hemophagocytic lymphohistiocytosis secondary to acute disseminated histoplasmosis in a patient with HIV/AIDS Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis Rate and Clinical Presentation of Macrophage Activation Syndrome in Patients With Systemic Juvenile Idiopathic Arthritis Treated With Canakinumab double-blind, placebo-controlled trial of the efficacy and safety of rilonacept in the treatment of systemic juvenile idiopathic arthritis Treatment of Epstein Barr virus-induced haemophagocytic lymphohistiocytosis with rituximab-containing chemo-immunotherapeutic regimens Novel use of rituximab in macrophage activation syndrome secondary to systemic lupus erythematosus Rituximab prophylaxis prevents corticosteroid-requiring chronic GVHD after allogeneic peripheral blood stem cell transplantation: results of a phase 2 trial Treatment of hemophagocytic lymphohistiocytosis with alemtuzumab in systemic lupus erythematosus Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study CP-690550, a Janus kinase inhibitor, suppresses CD4+ T-cell-mediated acute graft-versus-host disease by inhibiting the interferon-gamma pathway Reversal of CD8 T-cell-mediated mucocutaneous graft-versus-host-like disease by the JAK inhibitor tofacitinib Life-threatening NLRC4-associated hyperinflammation successfully treated with IL-18 inhibition Success with infliximab in treating refractory hemophagocytic lymphohistiocytosis Infliximab alleviates the mortality, mesenteric hypoperfusion, aortic dysfunction, and multiple organ damage in septic rats Safety and Efficacy of Infliximab Therapy in the Setting of Steroid-Refractory Acute Graft-versus-Host Disease Critical imbalance of TNF-alpha and soluble TNF receptor 1 in a patient with macrophage activation syndrome: potential implications for diagnostics and treatment Combination Therapy for Graft-versus-Host Disease Prophylaxis with Etanercept and Extracorporeal Photopheresis: Results of a Phase II Clinical Trial Chimeric antigen receptor-modified T cells for acute lymphoid leukemia Ponatinib Protects Mice From Lethal Influenza Infection by Suppressing Cytokine Storm Corticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis Hyperferritinemia as indicator for intravenous immunoglobulin treatment in reactive macrophage activation syndromes HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis Etoposide and Corticosteroid Combination Therapy Improves Acute Respiratory Distress Syndrome in Mice Cyclosporin Here, we discuss the pathogenesis of severe acute respiratory syndrome (SARS)-induced CRS, compare the CRS in COVID-19 with that in SARS and Middle East respiratory syndrome (MERS), and summarize the existing therapies for CRS.
    keywords: acute; cell; coronavirus; covid-19; crs; cytokine; il-6; patients; syndrome
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        item: #3245 of 7819
          id: cord-292894-p3099zpb
      author: de Oliveira, Rodrigo Ribeiro
       title: Lung ultrasound: an additional tool in COVID-19
        date: 2020
       words: 3311
      flesch: 43
     summary: Lung and pleural ultrasound has become very important in the assessment of patients in emergency and intensive care units. key: cord-292894-p3099zpb authors: de Oliveira, Rodrigo Ribeiro; Rodrigues, Thiago Potrich; da Silva, Paulo Savoia Dias; Gomes, Andrea Cavalanti; Chammas, Maria Cristina title: Lung ultrasound: an additional tool in COVID-19 date: 2020 journal: Radiol Bras DOI: 10.1590/0100-3984.2020.0051 sha: doc_id: 292894 cord_uid: p3099zpb Lung ultrasound is a well-defined diagnostic modality in the point of care emergency medicine concept.
    keywords: covid-19; figure; findings; lines; lung; ultrasound
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        item: #3246 of 7819
          id: cord-292898-6m97l2uz
      author: Ríos-Silva, Mónica
       title: COVID-19 mortality among pregnant women in Mexico: A retrospective cohort study
        date: 2020-09-23
       words: 3473
      flesch: 42
     summary: Positive pregnant patients did not have a higher risk of complications (admission to the ICU, pneumonia, or requirement for mechanical ventilation) or death than the controls. In bivariate analysis, pregnant patients with a positive test had a higher risk of death than pregnant patients with a negative test (relative risk (RR) = 3.87, 95% confidence interval (CI)
    keywords: covid-19; death; patients; risk; test; women
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        item: #3247 of 7819
          id: cord-292912-ufcvecwo
      author: Qiu, Ruijin
       title: Outcome reporting from protocols of clinical trials of Coronavirus Disease 2019 (COVID-19): a review
        date: 2020-03-08
       words: 1886
      flesch: 42
     summary: key: cord-292912-ufcvecwo authors: Qiu, Ruijin; Wei, Xuxu; Zhao, Mengzhu; Zhong, Changming; Zhao, Chen; Hu, Jiayuan; Li, Min; Huang, Ya; Han, Songjie; He, Tianmai; Chen, Jing; Shang, Hongcai title: Outcome reporting from protocols of clinical trials of Coronavirus Disease 2019 (COVID-19): a review date: 2020-03-08 journal: nan DOI: 10.1101/2020.03.04.20031401 sha: doc_id: 292912 cord_uid: ufcvecwo Objectives: To examine heterogeneity of outcomes in protocols of clinical trials of Coronavirus Disease 2019 (COVID-19) and to identify outcomes for prioritization in developing a core outcome set (COS) in this field. Conclusion: Outcome reporting in protocols of clinical trials of COVID-19 is inconsistent.
    keywords: license; medrxiv; perpetuity; preprint
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        item: #3248 of 7819
          id: cord-292929-s8pnm9wv
      author: Ashikalli, Louicia
       title: The indirect impact of COVID-19 on child health
        date: 2020-09-16
       words: 4938
      flesch: 48
     summary: The advantage of art programs like this is that once they are built by mental health professionals and child health specialists, they can be delivered in the communities using paraprofessionals who receive appropriate training. The universal use of face masks and the inclusion of younger children within any guidance is still being debated.
    keywords: care; children; covid-19; health; home; pandemic; parents; risk; school; support
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        item: #3249 of 7819
          id: cord-292952-z7ajsf2r
      author: Wong, Anselm
       title: COVID‐19 and toxicity from potential treatments: Panacea or poison
        date: 2020-05-12
       words: 1426
      flesch: 48
     summary: Remdesivir has been used previously to treat Ebola and recently has been prescribed to a small cohort study of COVID-19 patients. This pandemic has proven to be a challenge given that there is no immediate cure, no vaccine is currently available and medications or treatments being used are still undergoing clinical trials.
    keywords: covid-19; hydroxychloroquine; overdose; patients
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        item: #3250 of 7819
          id: cord-292978-qfw1uqvp
      author: Thakrar, Amit
       title: Thirty-Day Mortality Rate of Patients With Hip Fractures During the COVID-19 Pandemic: A Single Centre Prospective Study in the United Kingdom
        date: 2020-07-08
       words: 3420
      flesch: 51
     summary: key: cord-292978-qfw1uqvp authors: Thakrar, Amit; Chui, Karen; Kapoor, Akhil; Hambidge, John title: Thirty-Day Mortality Rate of Patients With Hip Fractures During the COVID-19 Pandemic: A Single Centre Prospective Study in the United Kingdom date: 2020-07-08 journal: J Orthop Trauma DOI: 10.1097/bot.0000000000001889 sha: doc_id: 292978 cord_uid: qfw1uqvp During the COVID-19 pandemic, the care of hip fracture patients remains a clinical priority. Our study demonstrated a significant increase in 30-day mortality among hip fracture patients during the first 30 days of the COVID-19 pandemic in the United Kingdom.
    keywords: covid-19; day; hip; mortality; patients; study
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        item: #3251 of 7819
          id: cord-292987-e481oa2i
      author: Repici, Alessandro
       title: Endoscopy units and the COVID-19 Outbreak: A Multi-Center Experience from Italy
        date: 2020-04-10
       words: 1130
      flesch: 37
     summary: The aim of this survey was to investigate the burden of COVID-19 on endoscopic activity in a highrisk area of COVID-19 outbreak, approaches to evaluating patients, adoption and compliance of HCP with protective measures, and initial possible viral transmission outcomes from endoscopy units within a large, community-based setting (both between patients and healthcare personnel and between healthcare personnel). All but one center Thirty-five (35) Regarding the preventive measures taken after the first Italian case (February 18 th , 2020), 5 endoscopy units (12.2%) did not take any measure, 29 In 27 (65.9%) endoscopy units, endoscopists were relocated to other hospital departments, for example, to assist with COVID-positive patients with pneumonia or in the emergency department.
    keywords: covid-19; endoscopy; personnel; units
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        item: #3252 of 7819
          id: cord-292988-q1yz9y8k
      author: Zumla, Alimuddin
       title: Reducing mortality and morbidity in patients with severe COVID-19 disease by advancing ongoing trials of Mesenchymal Stromal (stem) Cell (MSC) therapy - achieving global consensus and visibility for cellular host-directed therapies
        date: 2020-05-17
       words: 3163
      flesch: 21
     summary: Mesenchymal stem cells induce suppressive macrophages through phagocytosis in a mouse model of asthma Primary Analysis of a Phase 1/2 Study to Assess MultiStem® Cell Therapy, a Regenerative Advanced Therapy Medicinal Product (ATMP), in Acute Respiratory Distress Syndrome (MUST-ARDS) Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Design and validation of a consistent and reproducible manufacture process for the production of clinical-grade bone marrow-derived multipotent mesenchymal stromal cells Prospects and progress in cell therapy for acute respiratory distress syndrome Immunomodulation by therapeutic mesenchymal stromal cells (MSC) is triggered through phagocytosis of MSC by monocytic cells Minimal criteria for defining multipotent mesenchymal stromal cells. The international society for cellular therapy position statement Mesenchymal stem cells together with mycophenolate mofetil inhibit antigen presenting cell and T cell infiltration into allogeneic heart grafts Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities Effects of mesenchymal stem cells transplantation on cognitive deficits in animal models of Alzheimer's disease: A systematic review and meta-analysis Comorbidity and its impact on 1590 patients with Covid-19 in China: A Nationwide Analysis Are mesenchymal stromal cells immune cells Mesenchymal Stromal Cells Anno 2019:
    keywords: cells; covid-19; mesenchymal; mscs; patients; sars; stem; syndrome; trials
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        item: #3253 of 7819
          id: cord-292997-xbomgwzx
      author: Singh, Sandeep
       title: Takotsubo Syndrome in Patients with COVID-19: a Systematic Review of Published Cases
        date: 2020-10-06
       words: 2431
      flesch: 45
     summary: However, limited data on TTS in COVID-19 patients with only a handful of case reports promoted us to systematically review the published cases and pertinent outcomes. We searched PubMed/Medline, Web of Science, SCOPUS, and Google Scholar until June 15, 2020 for case reports and case series using these keywords: COVID-19, SARS-CoV-2, takotsubo syndrome/takotsubo cardiomyopathy, stressinduced cardiomyopathy, and broken heart syndrome.
    keywords: cases; covid-19; patients; syndrome; takotsubo; tts
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        item: #3254 of 7819
          id: cord-293055-8scoocvx
      author: Deressa, W.
       title: Availability of personal protective equipment and satisfaction of healthcare professionals during COVID-19 pandemic in Ethiopia
        date: 2020-11-03
       words: 7092
      flesch: 45
     summary: As there is limited published research on the relationship between healthcare workers satisfaction level with regard to the availability and use of appropriate PPE and associated factors, this study contributes additional knowledge in this area of research. Table 7 shows the relationship between the respondents PPE satisfaction level and independent factors for both bivariate and multivariable logistic regression analyses.
    keywords: availability; covid-19; healthcare; license; medrxiv preprint; ppe; preprint; study; use; workers
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        item: #3255 of 7819
          id: cord-293059-2iwzieqm
      author: Tao, Huaqiang
       title: Dysimmunity and inflammatory storm: Watch out for bone lesions in COVID-19 infection
        date: 2020-10-06
       words: 1818
      flesch: 29
     summary: However, studies on the correlation between pro-inflammatory cytokine responses and bone metabolism in COVID-19 patients are still lacking. In this special background, will inflammatory disorder and immune imbalance affect bone metabolism after COVID-19 infection?
    keywords: bone; cells; covid-19; immune; patients; sars
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        item: #3256 of 7819
          id: cord-293073-fu45h109
      author: Okano, Hideyuki
       title: Steps towards COVID-19 suppression
        date: 2020-06-22
       words: 631
      flesch: 30
     summary: Potential therapeutics for COVID-19 ➢ Dr. Terai and colleagues reviewed on therapeutic potential of mesenchymal stem cells (MSCs) and their exosomes in severe novel coronavirus disease 2019 (COVID-19) cases [5] . Prophylactic methods for COVID-19 ➢ Dr. Miyazawa and colleagues describe about herd immunity for COVID-19 pandemic.
    keywords: cov-2; covid-19
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        item: #3257 of 7819
          id: cord-293080-b4pxjrcj
      author: Zhang, Chunyan
       title: Establishing a high sensitivity detection method for SARS-CoV-2 IgM/IgG and developing a clinical application of this method
        date: 2020-09-18
       words: 4178
      flesch: 49
     summary: According to the reports of SARS antibody detection, the antibodies produced by human body mainly target N and S proteins, so using N and S proteins as antigens simultaneously may be able to detect more antibodies, thus improving the detection sensitivity. A novel coronavirus from patients with pneumonia in China Open access epidemiological data from the COVID-19 outbreak Understanding of COVID-19 based on current evidence Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series The outbreak of COVID-19: an overview Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis Early detection of antibodies against various structural proteins of the SARSassociated coronavirus in SARS patients Longitudinal profile of immunoglobulin G (IgG), IgM, and IgA antibodies against the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in patients with pneumonia due to the SARS coronavirus Profiles of antibody responses against severe acute respiratory syndrome coronavirus recombinant proteins and their potential use as diagnostic markers Clinical significance of IgM and IgG test for diagnosis of highly suspected COVID-19 infection SARS immunity and vaccination COVID-19 presents high risk to older persons The quest for an antibody-based HIV vaccine Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins We would like to thank the experts in the Wuhan Huoshenshan Hospital, First Hospital of Changsha and Chinese PLA General Hospital for their friendly help.
    keywords: antibody; cov-2; covid-19; detection; igg; igm; patients; sars; test
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        item: #3258 of 7819
          id: cord-293086-6282sb6b
      author: Liddell, Kathleen
       title: Who gets the ventilator? Important legal rights in a pandemic
        date: 2020-05-11
       words: 5506
      flesch: 43
     summary: They take the view that when Current controversy there are multiple critically ill patients, each with an equal ethical claim to be ventilated and not enough ventilators for all, doctors should prioritise patients who are more likely to recover swiftly (thereby clearing the ventilators for other patients in need). Approximately 2.5% of patients need mechanical ventilation while their body fights the infection.
    keywords: care; covid-19; doctors; law; nhs; patients; rights; treatment; triage; ventilator
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        item: #3259 of 7819
          id: cord-293117-hkkbqorv
      author: Hernández-García, Ignacio
       title: Characteristics of YouTube Videos in Spanish on How to Prevent COVID-19
        date: 2020-06-29
       words: 4096
      flesch: 45
     summary: key: cord-293117-hkkbqorv authors: Hernández-García, Ignacio; Giménez-Júlvez, Teresa title: Characteristics of YouTube Videos in Spanish on How to Prevent COVID-19 date: 2020-06-29 journal: Int J Environ Res Public Health DOI: 10.3390/ijerph17134671 sha: doc_id: 293117 cord_uid: hkkbqorv Objective: To analyze the characteristics of YouTube videos in Spanish on the basic measures to prevent coronavirus disease 2019 (COVID-19). [10, 11] public health emergencies, YouTube videos on such infections were viewed millions of times [9] [10] [11] .
    keywords: covid-19; health; information; measures; spanish; study; videos; youtube
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        item: #3260 of 7819
          id: cord-293127-c27qh5y7
      author: Monteleone, Pedro AA
       title: A review of initial data on pregnancy during the COVID-19 outbreak: implications for assisted reproductive treatments
        date: 2020
       words: 4519
      flesch: 37
     summary: The same day, the American Society for Reproductive Medicine (ASRM) published a bulletin suggesting that patients who are highly likely to suffer from COVID-19 (i.e., patients who were tested SARS-CoV-2 positive or who have been exposed to confirmed COVID-19 cases within 14 days of onset of their symptoms) should consider freezing oocytes or embryos and avoid embryo transfer until they are symptom-free; however, this recommendation was emphasized to not necessarily apply to suspected COVID-19 cases as symptoms of COVID-19 closely resemble those of other more common forms of respiratory disease (ASRM, 2020a). On March 15 2020, COVID-19 cases have been detected in all 30 countries of the European Union/European Economic Area and in the United Kingdom with a total of 39,768 cases and 1,727 deaths, of which 17,775 cases and 1,441 deaths occurred in Italy alone (European Centre for Disease Prevention and Control, 2020) .
    keywords: cases; coronavirus; cov-2; covid-19; infection; patients; pregnancy; sars; women
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        item: #3261 of 7819
          id: cord-293136-lfwqzf8m
      author: Escosa‐García, Luis
       title: Ten key points about COVID‐19 in children: the shadows on the wall
        date: 2020-08-13
       words: 3634
      flesch: 42
     summary: The coronavirus dilemma Three Hypotheses About Children COVID19 Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults Journal Pre-proof Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals Detection of Covid-19 in Children in Early SARS-CoV-2 Infection in Children Coronavirus Disease 2019 in Hubei, China COVID-19 Illness in Native and Immunosuppressed States: A Clinical-Therapeutic Staging Proposal Multicenter initial guidance on use of antivirals for children with COVID-19/SARS-CoV-2 Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review Remdesivir for the Treatment of Covid-19 -Preliminary Report Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19) Interleukin-6 blockade for severe COVID-19. Children aged <1 year had the highest prevalence of severe and critical disease (10.6%), and 53% of children in pediatric intensive care units (PICU) were infants.
    keywords: children; coronavirus; cov-2; covid-19; disease; infection; patients; sars
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        item: #3262 of 7819
          id: cord-293140-lp3l4iap
      author: Ghislandi, S.
       title: News from the front: Excess mortality and life expectancy in two major epicentres of the COVID-19 pandemic in Italy
        date: 2020-05-05
       words: 8337
      flesch: 56
     summary: As the COVID-19 outbreak spread aggressively in other countries like Spain, France, the UK, the US, country disparities in COVID-19 deaths became distinct. Accordingly, the media has constantly trying to dig out the underlying reasons behind the country differentials in COVID-19 deaths.
    keywords: age; bergamo; covid-19; deaths; epidemic; expectancy; life; mortality; number; preprint; years
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        item: #3263 of 7819
          id: cord-293145-b1rxh4bd
      author: Nouhjah, Sedigheh
       title: Challenges of diabetes care management in developing countries with a high incidence of COVID-19: A brief report
        date: 2020-05-19
       words: 1563
      flesch: 46
     summary: key: cord-293145-b1rxh4bd authors: Nouhjah, Sedigheh; Jahanfar, Shayesteh title: Challenges of diabetes care management in developing countries with a high incidence of COVID-19: A brief report date: 2020-05-19 journal: Diabetes Metab Syndr DOI: 10.1016/j.dsx.2020.05.012 sha: doc_id: 293145 cord_uid: b1rxh4bd BACKGROUND AND AIMS: Challenges of diabetes care management in developing countries with a high incidence of COVID-19: a brief report Highlights • COVID-19 pandemic may be a potentially diabetogenic situation and may worsen hyperglycemia and possibly diabetes-related complications •
    keywords: countries; covid-19; diabetes; patients
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        item: #3264 of 7819
          id: cord-293154-vudycqos
      author: Sinha, Sanjai
       title: Implementation of Video Visits During COVID-19: Lessons Learned From a Primary Care Practice in New York City
        date: 2020-09-17
       words: 4130
      flesch: 47
     summary: Design and participants: We included consecutive adults (age > 18) scheduled for video visits from March 16, 2020 to April 17, 2020 for COVID-19 and non-COVID-19 related complaints. Intervention: New processes were established to prepare the practice and patients for video visits.
    keywords: care; covid-19; data; patients; providers; study; video; video visits; visits
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        item: #3265 of 7819
          id: cord-293166-gkzebyda
      author: Hoz, Samer S.
       title: Letter to the Editor: “Beyond Containment: Tracking the Impact of Coronavirus Disease 2019 (COVID-19) on Neurosurgery Services in Iraq”
        date: 2020-11-03
       words: 1350
      flesch: 45
     summary: In addition, national public education plans for the de-stigmatization of the disease are needed, since many reports of transmission to hospital personnel have been traced back to patients who have denied their symptoms or exposure status. However, these measures are far from adequate and the hospital remains a full-house at all times, with at least 4 patients per hospital room, challenging the proper implementation of social distancing guidelines.
    keywords: cases; covid-19; disease; hospital
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        item: #3266 of 7819
          id: cord-293167-3bd3adip
      author: Nepal, Gaurav
       title: Neurological manifestations of COVID-19: a systematic review
        date: 2020-07-13
       words: 5554
      flesch: 43
     summary: Acute respiratory distress syndrome, acute heart injury or failure, acute kidney injury, sepsis, disseminated intravascular coagulation, and lifethreatening metabolic derangements have all been reported in COVID-19 patients, particularly among those with underlying comorbidities or advanced age In this systematic review, we evaluate various neurological manifestations reported in COVID-19 patients and hypothesize their underlying pathophysiology.
    keywords: acute; case; china; coronavirus; cov-2; covid-19; infection; manifestations; patients; sars; studies; study; symptoms
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        item: #3267 of 7819
          id: cord-293174-4ucqudn4
      author: Sun, Ziheng
       title: Community venue exposure risk estimator for the COVID-19 pandemic
        date: 2020-09-29
       words: 6318
      flesch: 53
     summary: 442 Public awareness of virus exposure risks is important. To inform and 445 assist, we propose a birthday-paradox-based probability model, coupled with a publicly-accessible web-446 based system to calculate community exposure risks in public gatherings.
    keywords: cases; community; correlation; cosre; counties; covid-19; data; exposure; new; pandemic; people; risk; time; virus
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        item: #3268 of 7819
          id: cord-293186-yxpkqbey
      author: Mamo, Yitagesu
       title: Perception Toward Quarantine for COVID-19 Among Adult Residents of Selected Towns in Southwest Ethiopia
        date: 2020-10-30
       words: 4597
      flesch: 48
     summary: Having training on COVID-19 was among a factor positively associated with perception toward quarantine ie, when we change the status of training from nontrained to trained the perception toward quarantine score will be increased by 2.76 units keeping other variables constant (β=2.76, p=0.005). Quantifying the impact of community quarantine on SARS transmission in Ontario: estimation of secondary case count difference and number needed to quarantine Estimation of the Transmission Risk of the 2019-nCoV and Its Implication for Public Health Interventions The Covid-19 Shock to Developing Countries: Towards a Whatever It Takes Programme for the Two-Thirds of the World's Population Being Left Behind Addressing the Impacts of COVID-19 in Food Crises Office for Africa; Scaling up coronavirus outbreak readiness in Ethiopia notification on Situational COVID 19 Update Covid-19 -the Law and Limits of Quarantine Preventive behaviors, and mental health in Turkey Risk perceptions of COVID-19 around the world World Health Organization (WHO) Factors influencing compliance with quarantine in Toronto during the 2003 SARS outbreak Letter to the Editor Aggregated COVID-19 suicide incidences in India: fear of COVID-19 infection is the prominent COVID-19-Related Suicides in Bangladesh Due to Lockdown and Economic Factors: case Study Evidence from Media Reports Lessons from the history of quarantine, from plague to influenza A Review Author (s): susan Chinn Review by: susan Chinn Source: journal of the Royal Statistical Public perceptions of quarantine: community-based telephone survey following an infectious disease outbreak Practice and Attitude towards Epilepsy and Associated Factors among Adults in Goncha Siso Enesie Woreda Rural Kebeles, East Gojjam Community knowledge and attitudes of epilepsy in rural and urban Mukono district, Uganda; a cross sectional study The impacts of vulnerability, perceived risk, and fear on preventive behaviours against COVID-19 Exploring the Associations Between Resilience, Dispositional Hope, Preventive Behaviours, Subjective Well-Being, and Psychological Health Among Adults During Early Stage of COVID-19 American Journal of Infection Control Middle East respiratory syndrome in South Korea during 2015: risk-related perceptions and quarantine attitudes Risk perception and compliance with quarantine during the SARS outbreak How to improve adherence with quarantine: rapid review of the evidence The authors are very grateful for Mizan-Tepi University, the study participants, data collectors and supervisors.
    keywords: community; covid-19; data; health; knowledge; perception; quarantine; respondents; score; study
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        item: #3269 of 7819
          id: cord-293259-o51fnvuw
      author: Sinaei, Reza
       title: Why COVID-19 is less frequent and severe in children: a narrative review
        date: 2020-09-25
       words: 7048
      flesch: 41
     summary: Genomic contributions and opportunities Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome Interleukin-1 receptor antagonist is associated with pediatric acute respiratory distress syndrome and worse outcomes in children with acute respiratory failure Identification of novel single nucleotide polymorphisms associated with acute respiratory distress syndrome by exome-seq Association of polymorphisms in genes of factors involved in regulation of splicing of cystic fibrosis transmembrane conductance regulator mRNA with acute respiratory distress syndrome in children with pneumonia Genetic gateways to COVID-19 infection: implications for risk, severity, and outcomes Differential expression of COVID-19-related genes in European Americans and African Americans Analysis of genetic host response risk factors in severe COVID-19 patients Down-regulated gene expression spectrum and immune responses changed during the disease progression in COVID-19 patients Genomewide association study of severe Covid-19 with respiratory failure The authors thank the staff and participants of this In a retrospective review of all COVID-19 patients treated at Wuhan union hospital until March 20, 2020, Mi et al. evaluated the correlation between prior exposures to MP and better clinical response in COVID-19 patients.
    keywords: adults; age; cases; children; coronavirus; cov-2; covid-19; disease; infection; mis; patients; pediatric; response; sars; syndrome
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        item: #3270 of 7819
          id: cord-293285-w8c3ma8l
      author: Lanza, F
       title: Reflection on passive immunotherapy in those who need most: some novel strategic arguments for obtaining safer therapeutic plasma or autologous antibodies from recovered COVID ‐19 infected patients
        date: 2020-05-14
       words: 1507
      flesch: 31
     summary: All rights reserved convalescent plasma, obtainable by plasmapheresis of recovered COVID 19 attacks, who would be volunteering to donate plasma or immunoglobulin-containing fractions has been proposed and implemented with success in COVID 19 cases (Chen et al, 2020; Shen et al, 2020 ; WHO, 2020; Casadevall et al, 2020; Seghatchian et al, 2020) . Based on this consideration, it might be postulated that either the preventive or the therapeutic use of convalescent plasma may be beneficial in chemotherapy-treated cancer patients, possibly mitigating the impact of COVID-19 (Dholaria B, et al, 2020) .
    keywords: covid; patients; plasma
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        item: #3271 of 7819
          id: cord-293315-kx4x2g24
      author: Colmenero, I.
       title: SARS‐CoV‐2 endothelial infection causes COVID‐19 chilblains: histopathological, immunohistochemical and ultraestructural study of 7 paediatric cases
        date: 2020-06-20
       words: 2534
      flesch: 37
     summary: All rights reserved Lymphocytic vascular damage was the hallmark feature in biopsies from our 7 patients with COVID-19 related chilblains. Histological features of COVID-19 related chilblains have been only scarcely described.
    keywords: cases; cells; chilblains; covid-19; patients; sars
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        item: #3272 of 7819
          id: cord-293333-mqoml9o5
      author: Scharbarg, Emeric
       title: From the hospital scale to nationwide: observability and identification of models for the COVID-19 epidemic waves
        date: 2020-10-03
       words: 5786
      flesch: 55
     summary: The subsystem (2) will be strongly observable if and only if the matrix has full rank, which happens if and only if The different notions of observability are peculiar of time delay systems. Since the health status is far from being homogeneous over a full country and since the health system consists in a network of major regional hospitals, it is worth to take advantage of the availability and agility of local hospital data rather than just merging them in some centralized information system.
    keywords: covid-19; dynamics; hospital; model; number; patients; time
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        item: #3273 of 7819
          id: cord-293359-6iw7dnz6
      author: Wang, Laureen Yi-Ting
       title: COVID-19 treatment with lopinavir–ritonavir resulting in sick sinus syndrome: a case report
        date: 2020-06-30
       words: 1876
      flesch: 45
     summary: Current efficacy and safety evidence of lopinavir–ritonavir as a treatment in COVID-19 patients is limited. Much of the evidence for treatment of COVID-19 patients remains uncertain.
    keywords: covid-19; lopinavir; patients; ritonavir; sinus; treatment
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        item: #3274 of 7819
          id: cord-293360-nmttgxlq
      author: García, Leidy Y.
       title: Acceptance of a COVID-19 vaccine: A multifactorial consideration
        date: 2020-11-10
       words: 520
      flesch: 25
     summary: In fact, the preliminary results of a Chilean case study on COVID-19 vaccine perception in the country, with a nationwide representative sample of 1097 individuals, shows that 87% are willing to vaccinate, a relatively high proportion and slightly lower than the rate found by García and Cerda Specifically, the willingness to vaccinate against SARS-CoV-2 depends on: (a) Availability, i.e. the actual existence of an effective vaccine and its country of origin; (b) Access to the vaccine, which could be limited by individual or governmental budgetary restrictions to finance preventive public health measures; (c) Perceived health risk, which depends on the intensity and severity of side effects and COVID-19 prevalence; (d) Information on benefits, risks and access pathways; (e) Previous experience with other vaccines and exposure to diseases, as this affects risk perception; and (f) Sociodemographic factors including age, education level, gender and more.
    keywords: covid-19; vaccine
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        item: #3275 of 7819
          id: cord-293367-0fe62h2f
      author: Henderson, Lauren A.
       title: American College of Rheumatology Clinical Guidance for Pediatric Patients with Multisystem Inflammatory Syndrome in Children (MIS‐C) Associated with SARS‐CoV‐2 and Hyperinflammation in COVID‐19. Version 1
        date: 2020-07-23
       words: 6235
      flesch: 30
     summary: All rights reserved RECOVERY trial) report that low to moderate dose dexamethasone significantly reduced mortality in COVID-19 patients requiring mechanical ventilation; but was reported after voting had occurred.(90, 91) Based on these studies that suggest that patients with severe COVID-19 pneumonia may benefit from immunomodulation with glucocorticoids, the Task Force achieved moderate consensus that glucocorticoid treatment could be considered in pediatric patients with severe COVID-19 and signs of hyperinflammation. The first webinar was used to confirm the target audience for the guidance, which focuses on clinicians in North America managing pediatric patients with inflammatory syndromes related to recent or concurrent infections with SARS-CoV-2.
    keywords: article; children; cov-2; covid-19; disease; guidance; mis; patients; pediatric; sars; syndrome; treatment
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        item: #3276 of 7819
          id: cord-293427-hwkmvo4p
      author: Zhang, Li
       title: The psychological typhoon eye effect during the COVID-19 outbreak in China: the role of coping efficacy and perceived threat
        date: 2020-10-27
       words: 5361
      flesch: 40
     summary: However, perceived threat, which tends to aggravate mental health, is positively correlated with mental health problems. In contrast, we hypothesized that coping efficacy, which tends to buffer mental health, is negatively correlated with mental health problems.
    keywords: covid-19; efficacy; exposure; health; health problems; level; problems; psychological; threat
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        item: #3277 of 7819
          id: cord-293440-qoo2t1wt
      author: Wilkinson, Tom
       title: ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A structured summary of a study protocol for a randomised controlled trial
        date: 2020-07-31
       words: 1866
      flesch: 45
     summary: Stage 1: To evaluate the safety and efficacy of candidate agents as add-on therapies to standard of care (SoC) in patients hospitalised with COVID-19 in a screening stage. Stage 2: To confirm the efficacy of candidate agents selected on the basis of evidence from Stage 1 in patients hospitalised with COVID-19 in an expansion stage.
    keywords: candidate; covid-19; protocol; stage; trial
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        item: #3278 of 7819
          id: cord-293481-bmfj50fb
      author: Malin, Jakob J.
       title: Remdesivir against COVID-19 and Other Viral Diseases
        date: 2020-10-14
       words: 9125
      flesch: 37
     summary: They found that the activity of remdesivir includes both contemporary human and highly divergent zoonotic CoVs and that natural variations in wild-type RdRp do not confer remdesivir resistance. Recently, the efficacy of remdesivir treatment was finally tested in a rhesus macaque model of SARS-CoV-2 infection (53) .
    keywords: antiviral; cell; clinical; cov-2; covid-19; data; drug; efficacy; mers; nucleoside; patients; remdesivir; rna; sars; study; treatment; trial; virus
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        item: #3279 of 7819
          id: cord-293500-z28bws23
      author: Guan, Wei-jie
       title: Cardiovascular comorbidity and its impact on patients with Covid-19
        date: 2020-04-27
       words: 463
      flesch: 27
     summary: We truly appreciate the comments from Sisnieguez et al., who have performed a further analysis on the potential association between cardiovascular comorbidities and the clinical outcomes of Covid-19 (in particular, the mortality) We also applaud the suggestion to thoroughly adjust for the potential confounding factors when interpreting the association between specific categories of cardiovascular comorbidities (e.g., hypertension) and the clinical outcomes of Covid-19.
    keywords: covid-19; patients
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        item: #3280 of 7819
          id: cord-293503-e7be12qb
      author: Xiang, Chao
       title: CT Findings in a Novel Coronavirus Disease (COVID-19) Pneumonia at Initial Presentation
        date: 2020-08-15
       words: 3322
      flesch: 46
     summary: Most types of COVID-19 pneumonia have abnormal radiographic changes at initial presentation, and CT features and patterns are similar to those of viral pneumonia. Although a patient with exposure history may be asymptomatic and obtained negative results of CT findings and viral nucleic acid test at initial presentation, the potential infection cannot be totally excluded, and performing repeating CT scan and coronavirus RNA test is needed.
    keywords: coronavirus; covid-19; features; patients; pneumonia; sars
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        item: #3281 of 7819
          id: cord-293522-gg706q8s
      author: Toumi, Mondher
       title: Commentary on “Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open label non-randomized clinical trial” by Gautret et al
        date: 2020-05-13
       words: 5239
      flesch: 48
     summary: The patients who refused to receive hydroxychloroquine were used as control patients, as were noneligible patients. [21] , we could assess the proportion of patients who were negative at 65% for hydroxychloroquine arm compared with 12.5% for the control arm, which is still statistically significant (p = 0.0012) and very clinically relevant.
    keywords: clinical; control; coronavirus; covid-19; health; hydroxychloroquine; patients; results; study; treatment
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        item: #3282 of 7819
          id: cord-293535-9bj5ev1a
      author: Wang, Yushu
       title: The influence of corticosteroid on patients with COVID-19 infection: A meta-analysis
        date: 2020-06-23
       words: 556
      flesch: 39
     summary: In addition, no statistically Which lessons shall we learn from the 2019 novel coronavirus outbreak? Clinical features and treatment of COVID-19 patients in northeast Chongqing Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan Clinical manifestations and sero-immunological characteristics of 155 patients with COVID-19 Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease Correction to: Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from 293535 cord_uid: 9bj5ev1a nan J o u r n a l P r e -p r o o f (SARS-CoV) and Middle Eastern respiratory syndrome (MERS)-CoV and did not investigate the effect of corticosteroids on mortality in COVID-19 patients.
    keywords: covid-19; patients
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        item: #3283 of 7819
          id: cord-293547-29i3u83s
      author: Pfaar, O
       title: COVID‐19 pandemic: Practical considerations on the organization of an allergy clinic – an EAACI/ARIA Position Paper
        date: 2020-06-12
       words: 8815
      flesch: 37
     summary: Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia Coronavirus disease (COVID-2019) situation reports Asthma and Allergy Foundation of America (aafa) Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Coronavirus disease (COVID-19) technical guidance: Patient management Eleven faces of coronavirus disease 2019 Considerations on Biologicals for Patients with allergic disease in times of the COVID-19 pandemic: an EAACI Statement Handling of allergen immunotherapy in the COVID-19 pandemic: An ARIA-EAACI statement Treatment of chronic RhinoSinusitis with nasal polyps (CRSwNP) in the COVID-19 pandemic -An EAACI Position Paper Is diet partly responsible for differences in COVID-19 death rates between and within countries? ARIA-EAACI statement on Asthma and COVID-19 COVID-19 in a designated infectious diseases hospital outside Hubei Province Distinct characteristics of COVID-19 patients with initial rRT-PCR-positive and rRT-PCR-negative results for SARS-CoV-2 Advanced forecasting of SARS-CoV-2-related deaths in Italy Is global BCG vaccination-induced trained immunity relevant to the progression of SARS-CoV-2 pandemic? Chronic rhinosinusitis (CRS) affects approximately 5-12% of the general population worldwide and is regarded as a chronic airway disease, that, according to WHO recommendations, may be a risk factor for COVID-19 patients
    keywords: allergy; article; asthma; care; case; clinic; copyright; cov-2; covid-19; disease; eaaci; health; infection; pandemic; patients; rights; risk; sars; symptoms; treatment
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        item: #3284 of 7819
          id: cord-293557-jcgc93it
      author: Recalde, Borja
       title: Histopathological findings in fatal COVID-19 severe acute respiratory syndrome: preliminary experience from a series of 10 Spanish patients
        date: 2020-08-23
       words: 1415
      flesch: 43
     summary: Mortality analyses Pathological findings of COVID-19 associated with acute respiratory distress syndrome COVID-19 autopsies Histopathology and ultrastructural findings of fatal COVID-19 infections Endothelial cell infection and endotheliitis in COVID-19 Lung pathology of fatal severe acute respiratory syndrome Histopathology of Middle East respiratory syndrome coronovirus (MERS-CoV) infection -clinicopathological and ultrastructural study COVID-19 infection: the perspectives on immune responses COVID19 coagulopathy in Caucasian patients Left ventricular performance in patients with severe acute respiratory syndrome: a 30-day echocardiographic follow-up study Contributors BR has sampled all postmortem biopsy and written the manuscript. However, autopsies in COVID-19 patients were only allowed under strict biosecurity regulations.
    keywords: cases; covid-19; lung; patients; sars
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        item: #3285 of 7819
          id: cord-293559-c78wcr8m
      author: Rego, Gabriel N. A.
       title: Current Clinical Trials Protocols and the Global Effort for Immunization against SARS-CoV-2
        date: 2020-08-25
       words: 9763
      flesch: 53
     summary: The current landscape of COVID-19 vaccine development shows that most CTPs are being developed in Asia (Table A1 ). Based on 50 current studies selected from the main clinical trial databases, this systematic review summarizes the global race for vaccine development against COVID-19.
    keywords: cov-2; covid-19; ctps; development; figure; iii; immunogenicity; mrna; phase; protein; safety; sars; study; trial; vaccine
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        item: #3286 of 7819
          id: cord-293570-gh6ykmea
      author: Gupta, Rajib K.
       title: Spectrum of podocytopathies in new-onset nephrotic syndrome following COVID-19 disease: a report of 2 cases
        date: 2020-08-04
       words: 3489
      flesch: 47
     summary: While all published case reports describe CG as the glomerular pathology, we describe a non-CG pathology (MCD) in one of our cases, thereby adding to the repertoire of renal pathology described in association with COVID-19 patients. Our case report describes a rare presenting complaint of COVID-19 patients with kidney involvementthat of new-onset nephrotic syndrome.
    keywords: biopsy; case; covid-19; disease; patients; podocyte; renal
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        item: #3287 of 7819
          id: cord-293575-h3wc7j4v
      author: Adrish, Muhammad
       title: Association of smoking status with outcomes in hospitalised patients with COVID-19
        date: 2020-10-05
       words: 2661
      flesch: 50
     summary: Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research. key: cord-293575-h3wc7j4v authors: Adrish, Muhammad; Chilimuri, Sridhar; Mantri, Nikhitha; Sun, Haozhe; Zahid, Maleeha; Gongati, Sudharsan; Fortuzi, Ked; Jog, Abhishrut Pramod; Purmessur, Pravish; Singhal, Ravish title: Association of smoking status with outcomes in hospitalised patients with COVID-19 date: 2020-10-05 journal: BMJ Open Respir Res DOI: 10.1136/bmjresp-2020-000716 sha: doc_id: 293575 cord_uid: h3wc7j4v INTRODUCTION:
    keywords: covid-19; disease; illness; patients; smokers; smoking; study
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        item: #3288 of 7819
          id: cord-293609-wymqvwjt
      author: Price, Alex
       title: Online Gambling in the Midst of COVID-19: A Nexus of Mental Health Concerns, Substance Use and Financial Stress
        date: 2020-07-13
       words: 7356
      flesch: 43
     summary: A cross-sectional online survey of 2005 gamblers, including a sub-sample of 1081 online gamblers (age 18 years and older), was administered to assess risky gambling behaviours and motivations, financial impacts from COVID-19, the influence of COVID-19 on online gambling, mental health concerns and substance use. Results show significant likelihood of online gambling among those classified as high-risk gamblers (according to the Problem Gambling Severity Index) and those with past experience of online gambling, though migration from land-based gambling was apparent.
    keywords: covid-19; et al; gamblers; gambling; health; risk; use
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        item: #3289 of 7819
          id: cord-293630-zc8huo1j
      author: Capone, Alessandro
       title: Simultaneous circulation of COVID-19 and flu in Italy: potential combined effects on the risk of death?
        date: 2020-08-05
       words: 2160
      flesch: 41
     summary: Demographic and clinical characteristics of died patients (including the number of comorbidities) are extremely relevant, especially to define those with a higher risk of mortality. Demographic and clinical characteristics of died patients (including the number of comorbidities) are extremely relevant, especially to define those with a higher risk of mortality.
    keywords: covid-19; influenza; mortality; patients; risk
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        item: #3290 of 7819
          id: cord-293634-4rryqbnu
      author: Rosen, Kelsey
       title: Delivering Telerehabilitation to COVID-19 Inpatients:A Retrospective Chart Review Suggests It Is a Viable Option
        date: 2020-07-16
       words: 3593
      flesch: 30
     summary: Patients assessed via telerehabilitation were provided individualized therapeutic exercises based on early anecdotal reports of high fatigability in patients with COVID-19 and clinical knowledge of therapeutic interventions for similar disease processes such as acute respiratory distress syndrome [3, 14, 15, 23] . The purpose of the inpatient telerehabilitation PT program for COVID-19 patients was to safely assess barriers to discharge, deliver patient education, and provide a home exercise program (HEP) all while minimizing staff exposure.
    keywords: covid-19; discharge; home; inpatient; patients; program; telerehabilitation; therapists
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        item: #3291 of 7819
          id: cord-293639-k96erjf1
      author: Mugnai, Giacomo
       title: Thoughts on Scientific Evidence in the COVID-19 Era
        date: 2020-06-24
       words: 699
      flesch: 41
     summary: A few years ago, in Italy, several clinical trials were run by the National Health System on the Di Bella therapy for cancer, 2 more because of the pressure of public opinion than objective preclinical observations. In any case, we have always to remember that, when scientific evidences are still weak, the risk of dispensing ineffective and unsafe drugs is just around the corner.
    keywords: covid-19; drugs; evidence
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        item: #3292 of 7819
          id: cord-293655-2ab7wdsk
      author: Mandic-Rajcevic, S.
       title: Contact tracing and isolation of asymptomatic spreaders to successfully control the COVID-19 epidemic among healthcare workers in Milan (Italy)
        date: 2020-05-08
       words: 6613
      flesch: 50
     summary: If the worker was absent for 14 days or more (same as COVID-19 positive workers) and/or showed typical symptoms, she or he was treated as a COVID-19 patient. For a smaller group of workers who reported their symptoms also in the 5 days leading to the positive NF swab, Figure 7 shows the body temperature and Figure 8 shows other reported symptoms (days -5 to 0).
    keywords: covid-19; days; hcws; license; preprint; sars; swab; symptoms; workers
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        item: #3293 of 7819
          id: cord-293690-pxiv0m7n
      author: Scala, Raffaele
       title: Italian pulmonologist units and COVID-19 outbreak: “mind the gap”!
        date: 2020-06-29
       words: 640
      flesch: 43
     summary: key: cord-293690-pxiv0m7n authors: Scala, Raffaele; Renda, Teresa; Corrado, Antonio; Vaghi, Adriano title: Italian pulmonologist units and COVID-19 outbreak: “mind the gap”! date: 2020-06-29 journal: Crit Care DOI: 10.1186/s13054-020-03087-y sha: doc_id: 293690 cord_uid: pxiv0m7n nan Raffaele Scala 1* , Teresa Renda 2 , Antonio Corrado 3 The outbreak of COVID-19 in Italy has shown the inadequacy of the health system to counterbalance a massive request for ICU care
    keywords: covid-19; patients
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        item: #3294 of 7819
          id: cord-293692-t5rfvyvj
      author: Kazi, Sajida
       title: The delights and perils of publishing, knowledge-sharing and critique during a pandemic: Observations from COVID-19 coagulopathies
        date: 2020-05-16
       words: 1964
      flesch: 30
     summary: World Health Organization, WHO Director-General's opening remarks at the mission briefing on COVID-19 Clinical Characteristics of Coronavirus Disease 2019 in China Naming the coronavirus disease (COVID-19) and the virus that causes it, World Heal The species Severe acute respiratory syndromerelated coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Hypercoagulability of COVID-19 patients in Intensive Care Unit. Evidence continues to accumulate as COVID-19 infections escalate, and as more countries present their findings.
    keywords: coronavirus; covid-19; data; disease; patients
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        item: #3295 of 7819
          id: cord-293701-u4ntxo0y
      author: Su, Shan
       title: Learning from the past: development of safe and effective COVID-19 vaccines
        date: 2020-10-16
       words: 8222
      flesch: 27
     summary: A pneumonia outbreak associated with a new coronavirus of probable bat origin Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein Effects of a SARS-associated coronavirus vaccine in monkeys Adenovirus-based vaccine prevents pneumonia in ferrets challenged with the SARS coronavirus and stimulates robust immune responses in macaques Immunization with modified vaccinia virus Ankara-based recombinant vaccine against severe acute respiratory syndrome is associated with enhanced hepatitis in ferrets Evaluation of modified vaccinia virus Ankara based recombinant SARS vaccine in ferrets A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge Prior immunization with severe acute respiratory syndrome (SARS)-associated coronavirus (SARS-CoV) nucleocapsid protein causes severe pneumonia in mice infected with SARS-CoV Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus Immunodominant SARS coronavirus epitopes in humans elicited both enhancing and neutralizing effects on infection in non-human primates A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice A SARS DNA vaccine induces neutralizing antibody and cellular immune responses in healthy adults in a phase I clinical trial Antibodies against trimeric S glycoprotein protect hamsters against SARS-CoV challenge despite their capacity to mediate FcgammaRII-dependent entry into B cells in vitro Antibody-dependent infection of human macrophages by severe acute respiratory syndrome coronavirus Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins Recent advances in the vaccine development against middle east respiratory syndrome-coronavirus Vaccines for the prevention against the threat of MERS-CoV Immunization with inactivated middle east respiratory syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus Single-dose, intranasal immunization with recombinant parainfluenza virus 5 expressing middle east respiratory syndrome coronavirus (MERS-CoV) spike protein protects mice from fatal MERS-CoV infection Molecular mechanism for antibodydependent enhancement of coronavirus entry Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial Safety and immunogenicity of a modified vaccinia virus Ankara vector vaccine candidate for Middle East respiratory syndrome: an open-label, phase 1 trial Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial Antibody-dependent enhancement of Ebola virus infection Infection of human lymphomononuclear cells by SARS-CoV-2 Differential chemokine expression following respiratory virus infection reflects Th1-or Th2-biased immunopathology Novel coronavirus infection (COVID-19) in humans: a scoping review and meta-analysis Dexamethasone for COVID-19: preliminary findings Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals Viral dynamics and immune correlates of COVID-19 disease severity Profile of IgG and IgM antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Nevada State Public Health Lab-led team studying COVID-19 reinfection COVID-19 Re-infection by a phylogenetically distinct SARS-CoV-2 variant, first confirmed event in South America COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing Symptomatic SARS-CoV-2 reinfection by a phylogenetically distinct strain Identification of human single-domain antibodies against SARS-CoV-2 Vaccine efficacy in senescent mice challenged with recombinant SARS-CoV bearing epidemic and zoonotic spike variants Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis Consensus summary report for CEPI/BC March 12-13, 2020 meeting: assessment of risk of disease enhancement with COVID-19 vaccines COVID-19: immunopathology and its implications for therapy SARS-CoV-2 vaccines: 'warp speed' needs mind melds not warped minds Receptor-binding domain of SARS-CoV spike protein induces long-term protective immunity in an animal model FDA. Similarly to COVID-19 vaccine developers, researchers first sought SARS vaccines based on inactivated virus, recombinant subunit proteins and recombinant vectors.
    keywords: antibodies; antibody; cell; coronavirus; cov; cov-2; covid-19; infection; protein; responses; rsv; sars; vaccine; virus
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        item: #3296 of 7819
          id: cord-293704-tnik6sd3
      author: Tey, Jeremy
       title: Navigating the challenges of the COVID-19 outbreak: perspectives from the radiation oncology service in singapore
        date: 2020-03-31
       words: 3514
      flesch: 48
     summary: It highlights the challenges that radiation oncology departments in Singapore face and the appropriate recommended responses. It highlights the challenges that radiation oncology departments in Singapore face and the appropriate recommended responses.
    keywords: covid-19; oncology; outbreak; patients; radiation; radiotherapy; singapore; staff; treatment
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        item: #3297 of 7819
          id: cord-293711-qgefn164
      author: Abdelmaksoud, Ayman
       title: Comment on “COVID‐19 and psoriasis: Is it time to limit treatment with immunosuppressants? A call for action”
        date: 2020-04-16
       words: 669
      flesch: 27
     summary: 13, 14 With the recent COVID-19 outbreak, dermatologists should prioritize and individualize treatment protocols to psoriatic patients based on diseases severity, patients medical conditions, and viral invasiveness. Older patients with moderate-to-severe disease are more prone to cardiovascular and neurological comorbidities, such as hypertension and dementia, respectively.
    keywords: covid-19; patients; psoriasis
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        item: #3298 of 7819
          id: cord-293717-j4w6mq0f
      author: Meza, Herbert Tejada
       title: Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain
        date: 2020-06-26
       words: 2329
      flesch: 50
     summary: We aimed to analyze the impact of the COVID-19 pandemic outbreak on hospital ischemic stroke admissions as well as the use of reperfusion therapies and inhospital mortality in tertiary referral hospitals from North-West Spain. We analyzed the impact of the COVID-19 pandemic on hospital stroke admissions and in-hospital mortality in tertiary referral hospitals from North-West Spain.
    keywords: admissions; covid-19; hospital; ischemic; spain; stroke; study
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        item: #3299 of 7819
          id: cord-293730-dlqo6fep
      author: Caratozzolo, Salvatore
       title: The impact of COVID-19 on health status of home-dwelling elderly patients with dementia in East Lombardy, Italy: results from COVIDEM network
        date: 2020-09-12
       words: 3730
      flesch: 42
     summary: Influenza Other Respir Viruses Coronavirus disease 2019 in elderly patients: characteristics and prognostic factors based on 4-week follow-up Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 Pneumonia in Wuhan, China Characteristics and outcomes of patients hospitalized for COVID-19 and cardiac disease in Northern Italy Clinical characteristics of coronavirus disease 2019 in China Hypertension and COVID-19 Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Association of inpatient use of angiotensin converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19 Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Italy: Non COVID-19 and COVID-19 patients differed for frequency of diabetes (18.5% vs. 37.9%, p < 0.001), COPD (7.3% vs. 18.9%, p < 0.001), and previous flu vaccination (56.7% vs. 37.9%, p < 0.001).
    keywords: covid-19; dementia; disease; health; home; patients; psy; study; symptoms
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        item: #3300 of 7819
          id: cord-293732-rxd1lyi7
      author: Manoj, M.G.
       title: Potential link between compromised air quality and transmission of the novel corona virus (SARS-CoV-2) in affected areas
        date: 2020-08-01
       words: 4182
      flesch: 39
     summary: Since UV index is much higher in Kerala (>10) in a polluted environment, the elevated levels of ground level ozone produced would further deteriorate air quality by which it infects the lungs to make a supporting platform for virus infection (Gerba et al., 2002; Hijnen et al., 2006; Tseng and Li, 2007) . Will Coronavirus Pandemic Diminish by Summer? Effects of air temperature and relative humidity on coronavirus survival on surfaces Roles of meteorological conditions in COVID-19 transmission on a worldwide scale Short-range airborne route dominates exposure of respiratory infection during close contact Solar ultraviolet radiation effects on biological systems Adsorption and reaction of trace gas-phase organic compounds on atmospheric water film surfaces: A critical review COVID-19 as a factor influencing air pollution Applied and Theoretical Aspects of Virus Adsorption to Surfaces Comparative inactivation of enteroviruses and adenovirus 2 by UV light Inactivation credit of UV radiation for viruses, bacteria and protozoan (oo)cysts in water: A review Clinical features of patients infected with 2019 novel coronavirus in Wuhan Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents Routes of transmission of influenza A H1N1, SARS CoV, and norovirus in air cabin: Comparative analyses Short-range airborne transmission of expiratory droplets between two people, Indoor Air Survival of calicivirus in foods and on surfaces: Experiments with feline calicivirus as a surrogate for norovirus Variations in surface ozone and NOx at Kannur: a tropical, coastal site in India Association between viral seasonality and meteorological factors Temperature, Humidity and Latitude Analysis to Predict Potential Spread and Seasonality for COVID-19 Transmission Potential of SARS-CoV-2 in Viral Shedding Observed at the University of Nebraska Medical Center The Potential role of Particulate Matter in the Spreading of COVID-19 in Northern Italy:
    keywords: air; covid-19; et al; humidity; surfaces; transmission; virus; viruses
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        item: #3301 of 7819
          id: cord-293736-nyvwv31m
      author: Méry, Geoffroy
       title: COVID-19: Underlying Adipokine Storm and Angiotensin 1-7 Umbrella
        date: 2020-07-21
       words: 5760
      flesch: 30
     summary: Oral or parenteral Ang1-7 supplementation could be a therapeutic option to diminish the low-grade systemic inflammation due to adipocyte dysfunction and attenuate the severity of ACE2-mediated injuries consecutive to SARS infection. High plasma levels of IL-6 and the absence of INF-1 have been noted in severe patients (47) , illustrating a sustained innate response that fails to achieve viral clearance and triggers ARDS.
    keywords: ace2; ang1; angiotensin; coronavirus; cov-2; covid-19; inflammation; obesity; patients; receptor; response; sars; syndrome
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        item: #3302 of 7819
          id: cord-293737-yaz13ikp
      author: Palaiodimos, L.
       title: Severe obesity is associated with higher in-hospital mortality in a cohort of patientswith COVID-19 in the Bronx, New York
        date: 2020-05-09
       words: 4077
      flesch: 51
     summary: Conclusions: In this cohort of hospitalized patients with COVID-19 in a minority-predominant population, severe obesity, increasing age, and male sex were associated with higher in-hospital mortality and in general worse in-hospital outcomes. confirmed COVID-19 were included. The most interesting finding of our analysis is that severe obesity is a significant factor for severe respiratory disease and death in hospitalized patients with COVID-19.
    keywords: covid-19; disease; license; obesity; patients; preprint
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        item: #3303 of 7819
          id: cord-293740-4c3yemi3
      author: Ferrando, Carlos
       title: Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS
        date: 2020-07-29
       words: 4340
      flesch: 50
     summary: We examined the clinical features, ventilatory management, and clinical outcomes of COVID-19 ARDS patients, and compared some results with other relevant studies in non-COVID-19 ARDS patients. Our findings in a cohort of over 700 patients are in line with preliminary studies of COVID-19 ARDS patients [23, 24] .
    keywords: ards; covid-19; day; lung; non; patients; pressure; studies; study
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        item: #3304 of 7819
          id: cord-293749-5i3ei9pn
      author: Alene, Kefyalew Addis
       title: Impact of the COVID-19 Pandemic on Tuberculosis Control: An Overview
        date: 2020-07-24
       words: 3431
      flesch: 40
     summary: The impact of COVID-19 on the health status of individuals, including on the functioning of the immune system [48, 49] , might be associated with a higher risk of developing active TB disease. Previous studies have shown that infections with viruses such as HIV and influenza play a role in the development of active TB disease, either directly after exposure to TB or through reactivation of latent TB infection
    keywords: control; covid-19; health; impact; pandemic; tuberculosis
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        item: #3305 of 7819
          id: cord-293787-kpn0hb8t
      author: Arulprakash, Enoch
       title: A Study on Fight Against COVID-19 from Latest Technological Intervention
        date: 2020-08-19
       words: 1702
      flesch: 42
     summary: (III) Prevention aspect: Monitoring and enforce social distancing through visual social distancing using deep learning and Computer vision. However, diagnosing using deep learning as a potential to compete forefront radiologist [14, 19] .
    keywords: covid-19; data; diagnosis; learning; machine
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        item: #3306 of 7819
          id: cord-293816-f86oo734
      author: Hughes, H.
       title: Uncomfortably numb: suicide and the psychological undercurrent of COVID-19
        date: 2020-05-21
       words: 963
      flesch: 55
     summary: The same study found that intentional exposure to COVID-19 is being used as a method of suicide (Ammerman et al. 2020) . However, the correlation between epidemics, mental health and suicide is not a new revelation.
    keywords: covid-19
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        item: #3307 of 7819
          id: cord-293822-axr9qu58
      author: Rolland, John S.
       title: COVID‐19 Pandemic: Applying a Multi‐Systemic Lens
        date: 2020-07-17
       words: 6471
      flesch: 44
     summary: For example, the ambiguity of being at risk versus an asymptomatic carrier would increase fears of transmitting COVID-19 to an older or chronically ill at risk family member. This necessitates ongoing monitoring and vigilance by family members for a protracted period. 2) Uncertainty regarding long-term complications (e.g. cardiac, respiratory, CNS).
    keywords: article; copyright; covid-19; disease; families; family; health; illness; life; living; members; pandemic; risk
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        item: #3308 of 7819
          id: cord-293838-avri3xuc
      author: Lippi, Giuseppe
       title: Association between environmental pollution and prevalence of coronavirus disease 2019 (COVID-19) in Italy
        date: 2020-04-27
       words: 1355
      flesch: 38
     summary: The results of this early analysis support the existence of a significant correlation between the number of COVID-19 cases and environmental pollution in Italy. Data on the overall number of positive COVID-19 cases per province was captured from the daily statics made available by the Italian Ministry of Health, on its official website, as of April 5, 2020 (http://www.salute.gov.it/imgs/C_17_pagineAree_5351_16_file.pdf).
    keywords: covid-19; number; preprint
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        item: #3309 of 7819
          id: cord-293852-r72c6584
      author: Greco, S.
       title: Noncoding RNAs implication in cardiovascular diseases in the COVID-19 era
        date: 2020-10-31
       words: 8171
      flesch: 32
     summary: However, in the heart of both SARS-CoV infected mice and of SARS patients, decreased ACE2-levels were observed [64] , suggesting a complex virus/receptor dynamic that needs to be elucidated. Interestingly, in the hearts of both SARS-CoV infected mice and SARS patients, macrophage infiltration with evidence of myocardial damage was observed [64] .
    keywords: ace2; cardiac; cardiovascular; cells; coronavirus; cov-2; covid-19; disease; expression; heart; human; infection; noncoding; patients; response; rna; rnas; sars
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        item: #3310 of 7819
          id: cord-293860-6kz0iws6
      author: Qutayba Almerie, Muhammad
       title: The Association between Obesity and Poor Outcome after COVID-19 Indicates a Potential Therapeutic Role for Montelukast
        date: 2020-05-27
       words: 2804
      flesch: 31
     summary: Evidence supporting montelukast as a candidate COVID-19 therapy in individuals with obesity: Patients affected by severe obesity share a common physiological response with patients with COVID-19 as both have raised concentrations of pro-inflammatory cytokines (e.g., TNF-a, IL1 and IL6) and T-helper-2 cytokines (IL4, IL10) Regulation of adipose tissue inflammation by interleukin 6 Circulating levels of MCP-1 and IL-8 are elevated in human obese subjects and associated with obesity-related parameters Inflammatory cytokines in general and central obesity and modulating effects of physical activity Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol Are more black, Asian and minority ethnic people dying with Covid-19 than might be expected?
    keywords: covid-19; drugs; immune; montelukast; obesity; patients; response
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        item: #3311 of 7819
          id: cord-293896-dz9lzlqq
      author: Mian, Hira
       title: Caring for older adults with multiple myeloma during the COVID-19 Pandemic: Perspective from the International Forum for Optimizing Care of Older Adults with Myeloma
        date: 2020-04-17
       words: 2316
      flesch: 26
     summary: Istituto Superiore di Sanità First case of COVID-19 in a patient with multiple myeloma successfully treated with tocilizumab Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Patients with cancer appear more vulnerable to SARS-COV-2: a multi-center study during the COVID-19 outbreak Immune parameters in multiple myeloma patients: influence of treatment and correlation with opportunistic infections Rapid assessment of regional SARS-CoV-2 community transmission through a convenience sample of healthcare workers, the Netherlands Evaluation of the Revised International Staging System in an independent cohort of unselected patients with multiple myeloma Complete response correlates with long-term progression-free and overall survival in elderly myeloma treated with novel agents: analysis of 1175 patients The relative importance of factors predicting outcome for myeloma patients at different ages: results from 3894 patients in the Myeloma XI trial Frailty and its definition: a worthy challenge A clinical prediction model for outcome and therapy delivery in transplant-ineligible patients with myeloma (UK Myeloma Research Alliance Risk Profile): a development and validation study Development of a Medicare Health Outcomes Survey Deficit-Accumulation Frailty Index and Its Application to Older Patients With Newly Diagnosed Multiple Myeloma A concise revised Myeloma Comorbidity Index as a valid prognostic instrument in a large cohort of 801 multiple myeloma patients Geriatric assessment predicts survival and toxicities in elderly myeloma patients: an International Myeloma Working Group report Gait speed, grip strength, and clinical outcomes in older patients with hematologic malignancies The modified Gait Efficacy Scale: establishing the psychometric properties in older adults Myeloma Patient Safety and the Coronovirus: International Myeloma Foundation COVID -19 and Multiple Myeloma: Frequently Asked Questions International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma Coronavirus Disease Covid-19: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention Clinical characteristics of COVID-19-infected cancer patients: A retrospective case study in three hospitals within Wuhan Coronavirus Disease 2019 in elderly patients: characteristics and prognostic factors based on 4-week follow-up The COVID-19 Pandemic in the US: A Clinical Update Causes of early death in multiple myeloma patients who are ineligible for high-dose therapy with hematopoietic stem cell support: A study based on the nationwide Danish Myeloma Database Multiple myeloma and infections: a population-based study on 9253 multiple myeloma patients Structured assessment of frailty in multiple myeloma as a paradigm of individualized treatment algorithms in cancer patients at advanced age Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 -COVID-NET, 14 States Characteristics of COVID-19 patients dying in Italy Report based on available data on April 9th, 2020.
    keywords: adults; covid-19; myeloma; outcomes; patients; risk
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        item: #3312 of 7819
          id: cord-293921-hj8oecmk
      author: Halayem, Soumeyya
       title: How Tunisians physicians of public health hospitals deal with COVID‐19 pandemic? Perceived stress and coping strategies
        date: 2020-06-27
       words: 702
      flesch: 57
     summary: [7] , and the French version of the brief COPE to asses coping strategies. Taking account of potential social desirability bias related to self-assessment methods, our population seemed to adopt appropriate coping strategies, although they reported more perceived stress than other studies using the same [9] or other instruments [4, 5] .
    keywords: physicians; stress
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        item: #3313 of 7819
          id: cord-293922-knzv4jvj
      author: Zuo, Y.
       title: Plasma tissue plasminogen activator and plasminogen activator inhibitor-1 in hospitalized COVID-19 patients
        date: 2020-09-02
       words: 3051
      flesch: 44
     summary: A recent study of hospitalized COVID-19 patients also detected elevations of both PAI-1 and tPA, particularly among critically-ill COVID-19 patients [23] ; however, the mechanistic role of the elevated tPA among COVID-19 patients was not specifically investigated [23] . It has been suggested that high PAI-1 levels overcome the effects of local tPA and produce a net prothrombotic hypofibrinolytic state in COVID-19 patients [23] .
    keywords: covid-19; fibrinolysis; levels; medrxiv; patients; preprint; tpa
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        item: #3314 of 7819
          id: cord-293942-n5ypkftc
      author: Takoi, Hiroyuki
       title: Favipiravir-induced fever in coronavirus disease 2019: A report of two cases
        date: 2020-09-28
       words: 1163
      flesch: 50
     summary: A definition of drug fever is a disorder characterized by fever coinciding with the administration of a drug and disappearing after the discontinuation of the drug, when no other cause for the fever is evident after a careful physical examination and laboratory investigation, with a period of 1.3 ± 1.1 days from discontinuation of the causative drug to pyretolysis (Makowiak and LeMaistre, 1987) . Drug fever can be ruled out if pyretolysis is not confirmed within 72 h after the discontinuation of the drug (Mourad et al., 2003) .
    keywords: covid-19; favipiravir; fever
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        item: #3315 of 7819
          id: cord-293964-hz5uow2b
      author: Hermann, Matthias
       title: Feasibility and Efficacy of Cardiopulmonary Rehabilitation following COVID-19
        date: 2020-07-22
       words: 2747
      flesch: 45
     summary: [8] [9] [10] However, as the whole COVID-19 condition is so new, there are scarce data available about feasibility, safety and success of in-patient CR in COVID-19 patients. Therefore, we retrospectively analyzed a cohort of COVID-19 patients in a single center inpatient rehabilitation clinic and describe performance and outcome during CR.
    keywords: covid-19; days; health; patients; rehabilitation; ventilation
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        item: #3316 of 7819
          id: cord-293967-t0216n2m
      author: Moorthy, Arumugam
       title: COVID 19 and Ethnicity: Spot light on the global rheumatology issues in developing and developed countries
        date: 2020-05-30
       words: 2617
      flesch: 40
     summary: However, data suggest the medications used in rheumatology, such as tocilizumab and anakinra, may have some beneficial effect in COVID-19 patients (24, 25) . Studies demonstrated patient related factors may play a key role in adherence to treatments among BAME rheumatology patients (19, 20) .
    keywords: article; bame; countries; covid-19; health; patients
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        item: #3317 of 7819
          id: cord-293986-skp6tiun
      author: Millard, Hun
       title: COVID-19 Psychiatric Patients: Impact of Variability in Testing on Length of Hospital Stay and Disposition Back to Congregate Care Settings
        date: 2020-07-24
       words: 1138
      flesch: 36
     summary: The new challenges of the COVID pandemic has forced hospitals to adapt patient care, especially in congregate psychiatric settings. Although testing variability has been explored in the literature, we report here the direct impact of testing variability on patient care in inpatient psychiatry (Zou et al., 2020) .
    keywords: care; covid; patients
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        item: #3318 of 7819
          id: cord-293990-h2o3v5gp
      author: Schoenbrunner, Anna
       title: Considerations for Pediatric Craniofacial Surgeons During the COVID-19 Outbreak
        date: 2020-05-11
       words: 1812
      flesch: 31
     summary: 9,10 Current recommendations for PPE use during surgical procedures on suspected or confirmed COVID-19 patients suggest the use of either a N95 or powered air-purifying respirator (PAPR). Thirty states and the District of Columbia provide recommendations or orders regarding the postponement of elective procedures.
    keywords: covid-19; patients; procedures; risk; state
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        item: #3319 of 7819
          id: cord-293997-4wjf1znf
      author: Asai, Nobuhiro
       title: Clinical manifestations and radiological features by chest computed tomographic findings of a novel coronavirus disease-19 pneumonia among 92 Japanese people
        date: 2020-08-20
       words: 1671
      flesch: 58
     summary: COVID-19 pneumonia Patients and methods For the purpose of identifying clinical manifestations and radiological findings of COVID-19 pneumonia, we reviewed all cases of COVID-19 pneumonia which were published by the homepage of the Japanese Association for Infectious Diseases from Feb 5 2020 until April 30 2020, including our cases. We concluded that COVID-19 pneumonia patients show typically GGO, peripheral, bilateral CT, computed tomography; GGO, ground-glass opacity; SD, standard deviation.
    keywords: covid-19; patients; pneumonia
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        item: #3320 of 7819
          id: cord-294023-knaxr7t0
      author: Murri, Rita
       title: Social media as a tool for scientific updating at the time of COVID pandemic: Results from a national survey in Italy
        date: 2020-09-03
       words: 2074
      flesch: 46
     summary: key: cord-294023-knaxr7t0 authors: Murri, Rita; Segala, Francesco Vladimiro; Del Vecchio, Pierluigi; Cingolani, Antonella; Taddei, Eleonora; Micheli, Giulia; Fantoni, Massimo title: Social media as a tool for scientific updating at the time of COVID pandemic: Results from a national survey in Italy date: 2020-09-03 journal: PLoS One DOI: 10.1371/journal.pone.0238414 sha: doc_id: 294023 cord_uid: knaxr7t0 In the face of the rapid evolution of the COVID-19 pandemic, healthcare professionals on the frontline are in urgent need of frequent updates in the accomplishment of their practice. 70% (n = 261) of respondents reported that their use of social media to seek medical information increased during the pandemic.
    keywords: covid-19; information; media; pandemic
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        item: #3321 of 7819
          id: cord-294057-fbox3a5q
      author: Schlegl, Sandra
       title: Bulimia nervosa in times of the COVID‐19 pandemic—Results from an online survey of former inpatients
        date: 2020-08-07
       words: 2819
      flesch: 44
     summary: The COVID‐19 pandemic might pose special challenges to patients with eating disorders (EDs) by interfering with daily routines. The aim of this study was to investigate the impact of the current pandemic on patients with bulimia nervosa (BN).
    keywords: covid-19; eating; pandemic; patients
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        item: #3322 of 7819
          id: cord-294064-vdpak3fm
      author: Iqbal, Muhammad Rafaih
       title: Single centre concept of ‘cold site’ elective surgery during the peak of COVID-19 pandemic: A cohort study
        date: 2020-10-06
       words: 3039
      flesch: 56
     summary: 19.56% (63/322) of the patients were deemed unfit for CS elective surgery (Figure 2 ). As these systems got overwhelmed with the emergency care of the infected patients, widespread cancellations of elective surgery occurred.
    keywords: covid-19; pandemic; patients; study; surgery
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        item: #3323 of 7819
          id: cord-294073-65h2mkdy
      author: Ke, Jia
       title: Strategies and recommendations for the management of gastrointestinal surgery during the COVID-19 pandemic: experience shared by Chinese surgeons
        date: 2020-07-03
       words: 4156
      flesch: 35
     summary: Most importantly, the task force should have overall control regarding the balance between the resources being used for COVID-19 patients (e.g. personal protection equipment [PPE] , ventilators, intensive care unit [ICU] beds, physicians) and those that would be used for surgical patients. Clinical characteristics of coronavirus disease 2019 in China Detection of SARS-CoV-2 in different types of clinical specimens Evidence for gastrointestinal infection of SARS-CoV-2 Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study A multidisciplinary team approach for triage of elective cancer surgery at the Massachusetts General Hospital during the novel coronavirus COVID-19 Outbreak Recommendations for general surgery clinical practice in novel coronavirus pneumonia situation Implications of COVID-19 for patients with pre-existing digestive diseases Advice for Endoscopy Teams during COVID-19 COVID-19 outbreak and surgical practice: unexpected fatality in perioperative period Characterization of smoke generated during the use of surgical knife in laparotomy surgeries COVID-19: Guidance for Triage of Non-Emergent Surgical Procedures.
    keywords: cancer; covid-19; patients; precautions; procedures; risk; sars; surgery
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        item: #3324 of 7819
          id: cord-294094-ndahvsz7
      author: McQueen, Sydney A.
       title: The Person Behind the Personal Protective Equipment
        date: 2020-08-11
       words: 1025
      flesch: 66
     summary: Good patient care requires an understanding for patients' feelings and fears, their financial situations, and social supports. In the same way, good health systems appreciate the multidimensionality of their health care workers.
    keywords: care; covid-19; patients
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        item: #3325 of 7819
          id: cord-294108-uvnh0s9r
      author: Dube, Taru
       title: Repurposed Drugs, Molecular Vaccines, Immune‐Modulators, and Nanotherapeutics to Treat and Prevent COVID‐19 Associated with SARS‐CoV‐2, a Deadly Nanovector
        date: 2020-10-25
       words: 13897
      flesch: 38
     summary: COVID-19 patients seeking intensive care unit (ICU) are particularly older and more likely to carry pre-existing comorbid conditions like hypertension and related heart diseases followed by diabetes. To date, apart from the emergency use approval of the antiviral drug favilavir in China, India, Russia, and parts of the Middle East and the emergency use approval of remdesivir by the US-FDA and Japan in COVID-19 patients, there are no approved therapeutic molecules to treat the COVID-19 pandemic.
    keywords: care; cells; cov-2; covid-19; covid-19 patients; disease; dose; drug; efficacy; host; human; iii; infection; patients; phase; potential; protein; response; rna; safety; sars; therapeutics; treatment; trial; use; vaccine; virus
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        item: #3326 of 7819
          id: cord-294115-7t7kubf6
      author: Miralles, Oriol
       title: Unmet needs, health policies, and actions during the COVID-19 pandemic: a report from six European countries
        date: 2020-10-15
       words: 7261
      flesch: 45
     summary: Address the disparities in pay and job security between health care and social care workers. As a result, at the beginning, 19 single-purpose infectious disease hospitals were established across the country for COVID-19 patients, supplemented by 70 infectious disease wards.
    keywords: age; care; cases; countries; cov-2; covid-19; health; homes; impact; march; nursing; pandemic; patients; people; sars; support
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        item: #3327 of 7819
          id: cord-294118-tm2kesum
      author: Lemos, Daniele Rocha Queiros
       title: Health system collapse 45 days after the detection of COVID-19 in Ceará, Northeast Brazil: a preliminary analysis
        date: 2020-07-03
       words: 2362
      flesch: 52
     summary: The study used an ecological design to compare confirmed COVID-19 cases and deaths to bed occupancy rates in Ceará. Epidemic week 20 had the highest number of reported cases and the peak of deaths.
    keywords: 2020; cases; ceará; covid-19; days; deaths; health; number
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        item: #3328 of 7819
          id: cord-294136-e69ao8j0
      author: Han, Dongsheng
       title: COVID-19: Insight into the asymptomatic SARS-COV-2 infection and transmission
        date: 2020-08-27
       words: 5231
      flesch: 35
     summary: Four studies suggested that the virus can be transmitted by asymptomatic patients for at least two consecutive generations, indicating its strong infectivity. The majority of asymptomatic patients appear to have a milder clinical course during hospitalization, but the severity of the symptoms of the secondary patients infected by SARS-COV-2 from asymptomatic patients varies with their physical constitution.
    keywords: asymptomatic; cases; china; coronavirus; cov-2; covid-19; infection; patients; sars; transmission
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        item: #3329 of 7819
          id: cord-294139-78c5h7la
      author: Yamakawa, Mai
       title: Clinical Characteristics of Stroke with COVID-19: A Systematic Review and Meta-Analysis
        date: 2020-08-29
       words: 3100
      flesch: 38
     summary: Forest plots for characteristics of stroke patients with COVID-19 (random-effects model); (A): The frequency of stroke Days from COVID-19 symptom onset to stroke; (C): D-dimer; (D): Case fatality rate Funding: None. Numerous case reports and retrospective cohort studies have been published with mixed characteristics of COVID-19 patients with stroke regarding age, comorbidities, treatment, and outcome.
    keywords: case; covid-19; patients; risk; stroke; studies; study
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        item: #3330 of 7819
          id: cord-294159-721il1e2
      author: Kumar, Kanta
       title: COVID-19 and ethnicity: challenges in rheumatology
        date: 2020-06-17
       words: 1218
      flesch: 41
     summary: Vitamin D deficiency and obesity, which are common among BAME patient groups, make this group more susceptible [3] . Current ongoing studies indicate the possibility of a genetic link to increase predisposition to COVID 19 among BAME patients [1] .
    keywords: bame; communities; covid-19; patients
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        item: #3331 of 7819
          id: cord-294180-t5bncpo4
      author: Neto, Leônidas Oliveira
       title: Aging and Coronavirus: Exploring Complementary Therapies to Avoid Inflammatory Overload
        date: 2020-06-26
       words: 3503
      flesch: 24
     summary: Furthermore, reducing sedentary behavior and engaging in exercise may increasing the production of systemic anti-inflammatory cytokines and help to combat inflammation (63, 64) by increasing innate immune function (65) and decreasing the chronic inflammation related to various diseases (66) . Adipose tissue: immune function and alterations caused by obesity Endocrine and metabolic link to coronavirus infection Kidney disease is associated with in-hospital death of patients with COVID-19 Similarity in case fatality rates (CFR) of COVID-19/SARS-COV-2 in Italy and China Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Diagnosis and clinical management of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection: an operational recommendation of Peking Union Medical College Hospital (V2.0): Working Group Novel Coronavirus, Peking Union Medical Colle Interacting mediators of allostasis and allostatic load: towards an understanding of resilience in aging Allostasis and allostatic load: expanding the discourse on stress and cardiovascular disease Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies Associations between immune-suppressive and stimulating drugs and novel COVID-19-a systematic review of current evidence Metronidazole a potential novel addition to the COVID-19 treatment regimen The use of antiinflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): the experience of clinical immunologists from China The role of oxidative stress in the aging process Inflammation, genetic background and longevity Clinical advances in sex-and gender-informed medicine to improve the health of all: a review The lethal sex gap: COVID-19 24.
    keywords: adults; aging; covid-19; exercise; immune; inflammation; patients; review; system
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        item: #3332 of 7819
          id: cord-294184-jte9xx5e
      author: Macleod, Jack
       title: Surgery during COVID-19 crisis conditions: can we protect our ethical integrity against the odds?
        date: 2020-06-12
       words: 2749
      flesch: 44
     summary: Good Practice for Surgeons and Surgical Teams -Royal College of Surgeons Clinical guide for the management of cardiothoracic surgery patients during the Coronavirus pandemic Coronary artery bypass grafting vs. percutaneous coronary intervention for patients with three-vessel disease: final fiveyear follow-up of the SYNTAX trial Clinical outcomes with percutaneous coronary revascularization vs coronary artery bypass grafting surgery in patients with unprotected left main coronary artery disease: a meta-analysis of 6 randomized trials and 4,686 patients Endovascular versus open repair of abdominal aortic aneurysm in 15-years' follow-up of the UK endovascular aneurysm repair trial 1 (EVAR trial 1): a randomised controlled trial The heart score for the assessment of patients with chest pain in the emergency department: a multinational validation study Principles of biomedical ethics The right and the good Origin and uses of primum non nocere--above all, do no harm! The lack of clear guidance lead to discussion in regards to how we treat urgent cardiac surgery patients to the best of our department's ability.
    keywords: covid-19; patients; principles; risk; standard; surgery
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        item: #3333 of 7819
          id: cord-294190-s337jpbo
      author: Rubinstein, Samuel
       title: The COVID-19 & Cancer Consortium (CCC19): a collaborative effort to understand the effects of COVID-19 on patients with cancer
        date: 2020-04-29
       words: 1852
      flesch: 30
     summary: key: cord-294190-s337jpbo authors: Rubinstein, Samuel; Steinharter, John A.; Warner, Jeremy; Rini, Brian I.; Peters, Solange; Choueiri, Toni K. title: The COVID-19 & Cancer Consortium (CCC19): a collaborative effort to understand the effects of COVID-19 on patients with cancer date: 2020-04-29 journal: Cancer Cell DOI: 10.1016/j.ccell.2020.04.018 sha: doc_id: 294190 cord_uid: s337jpbo Summary National and international consortia will play a key role in understanding the effects of the coronavirus disease 2019 (COVID-19) pandemic on cancer patients. Current evidence suggests that the effect of the pandemic on cancer patients has been profound.
    keywords: cancer; ccc19; covid-19; data; patients
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        item: #3334 of 7819
          id: cord-294242-amj0ohw3
      author: Li, Jia
       title: Electrophysiology in the time of coronavirus: coping with the great wave.
        date: 2020-03-30
       words: 3281
      flesch: 50
     summary: During the initial months of 2020, Wenzhou experienced the greatest concentration of COVID-19 cases of any Chinese city outside the Hubei province. In each of the electrophysiology labs, routine activity was cancelled as soon as the country detected significant numbers of COVID-19 cases.
    keywords: author; covid-19; funder; license; medrxiv; peer; perpetuity; preprint
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        item: #3335 of 7819
          id: cord-294304-9w6zt778
      author: Doanvo, Anhvinh
       title: Machine Learning Maps Research Needs in COVID-19 Literature
        date: 2020-09-16
       words: 5513
      flesch: 39
     summary: 19 Topic modeling helped characterize differences between research topics discussed in 21 COVID-19 and non-COVID-19 abstracts. Third, defining primary topics in COVID-19 research solely by a select group of 3 influential studies or on narrow correlations between a few metadata keywords at a time is 4 insufficient because 1) topics may be broader than one or several highly influential studies and 2) 5 topics may be comprised of complex correlations mapped between hundreds of different 6 keywords.
    keywords: abstracts; coronavirus; covid-19; data; research; sars; studies; terms; topics
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        item: #3336 of 7819
          id: cord-294333-6azdm42x
      author: Wang, S
       title: Sleep disturbances among medical workers during the outbreak of COVID-2019
        date: 2020-05-06
       words: 3012
      flesch: 48
     summary: We observed that, during the outbreak of COVID-19, sleep disturbance was highly prevalent among paediatric healthcare workers, and sleep disturbance was independently associated with being an only child, exposure to COVID-19 patients and depression. Paediatric healthcare workers also experience great work pressure.
    keywords: covid-19; depression; disturbance; healthcare; sleep; workers
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        item: #3337 of 7819
          id: cord-294336-fqobpo47
      author: Soy, Mehmet
       title: Hemophagocytic lymphohistiocytosis: a review inspired by the COVID-19 pandemic
        date: 2020-06-25
       words: 5795
      flesch: 36
     summary: On the other hand, unlike primary HLH patients, observed differences in the pattern of T lymphocyte activation and differentiation in sHLH patients may imply differences in the pathogenesis of these two conditions. Numerous serum proinflammatory cytokine levels, including IL-1, IL-2, IL-6, IL-12, IL-16, IL-18, TNF-, and IFN-γ, were found to be significantly high in HLH patients sera.
    keywords: activation; covid-19; cytokine; diagnosis; hlh; lymphohistiocytosis; macrophage; mas; patients; phlh; syndrome; treatment
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        item: #3338 of 7819
          id: cord-294349-ps3qlho2
      author: Al-Sharif, Eman
       title: Ocular tropism of coronavirus (CoVs): a comparison of the interaction between the animal-to-human transmitted coronaviruses (SARS-CoV-1, SARS-CoV-2, MERS-CoV, CoV-229E, NL63, OC43, HKU1) and the eye
        date: 2020-09-03
       words: 7059
      flesch: 40
     summary: In a previous case-control study conducted in China among healthcare providers who were taking care of SARS patients, all the 69 providers adhering to the four infection control measures (gown, gloves, mask and hand hygiene practices) did not contract the infection, while all the 13 infected staff omitted at least one of the four control measures [65] . In terms of ocular manifestations, a study published by Wu and colleagues on ocular findings in COVID-19 patients showed that approximately one-third of patients (12/38, 31.6%) had eye manifestations such as conjunctival redness, chemosis, tearing and increased secretions.
    keywords: conjunctival; coronavirus; cov-2; covid-19; disease; eye; human; infection; mers; patients; sars; studies; symptoms; transmission
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        item: #3339 of 7819
          id: cord-294350-6veeygzp
      author: Yu, Caizheng
       title: Clinical Characteristics, Associated Factors, and Predicting COVID-19 Mortality Risk: A Retrospective Study in Wuhan, China
        date: 2020-05-27
       words: 3286
      flesch: 39
     summary: This study investigates the clinical characteristics and risk factors for COVID-19 mortality, and establishes a novel scoring system to predict mortality risk in COVID-19 patients. This study investigates the clinical characteristics and risk factors for COVID-19 mortality, and establishes a novel scoring system to predict mortality risk in COVID-19 patients.
    keywords: covid-19; covid-19 mortality; mortality; patients; pct; risk; study
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        item: #3340 of 7819
          id: cord-294360-1oymweb0
      author: Mair, Frances S
       title: Multimorbidity and the COVID-19 pandemic – An urgent call to action
        date: 2020-10-13
       words: 953
      flesch: 43
     summary: Some early studies have started the process of developing COVID-19 risk stratification for those with multimorbidity. 2. Public health and policy advice that defines and classifies who is at high risk of COVID-19 needs to highlight the increased risks for those living with multimorbidity.
    keywords: covid-19; multimorbidity
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        item: #3341 of 7819
          id: cord-294371-xot2oj2t
      author: Citgez, Bulent
       title: Management of Breast Cancer during the COVID-19 Pandemic
        date: 2020-06-10
       words: 2226
      flesch: 43
     summary: In this review, we tried to explain how to prevent the negative effects of the COVID-19 pandemic on the diagnosis and treatment of breast cancer patients. Medications in breast cancer patients receiving NAC can suppress the development of a fever or other symptoms, and COVID-19 disease may remain asymptomatic until they develop sepsis.
    keywords: breast; cancer; covid-19; pandemic; patients; treatment
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        item: #3342 of 7819
          id: cord-294400-65lwy0dg
      author: Cowan, Henry R.
       title: Is schizophrenia research relevant during the COVID-19 pandemic?
        date: 2020-04-04
       words: 1095
      flesch: 45
     summary: This commentary argues that schizophrenia research is more relevant than ever during this public health crisis, because of the likelihood that the COVID-19 pandemic may lead to increased incidence of psychotic disorders. key: cord-294400-65lwy0dg authors: Cowan, Henry R. title: Is schizophrenia research relevant during the COVID-19 pandemic? date: 2020-04-04 journal:
    keywords: covid-19; pandemic; research; schizophrenia
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        item: #3343 of 7819
          id: cord-294422-hsqphc3t
      author: Sandesh, Ram
       title: Impact of COVID-19 on the Mental Health of Healthcare Professionals in Pakistan
        date: 2020-07-02
       words: 1854
      flesch: 50
     summary: Novel coronavirus (2019-nCoV) situation reports Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak Public responses to the novel 2019 coronavirus (2019-nCoV) in Japan: mental health consequences and target populations Mental health survey of 230 medical staff in a tertiary infectious disease hospital for COVID-19 The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed Psychological impact of the 2015 MERS outbreak on hospital workers and quarantined hemodialysis patients Vicarious traumatisation in the general public, members, and non-members of medical teams aiding in COVID-19 control Pandemic fear and COVID-19: mental health burden and strategies Safarizadeh MM: Stress, anxiety and depression among medical university students and its relationship with their level of happiness The psychological impact of severe acute respiratory syndrome outbreak on healthcare workers in emergency departments and how they cope Severe acute respiratory syndrome (SARS) and healthcare workers Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019 The general public undertakes such safety measures, but health care professionals (HCPs) are unfortunately left exposed to deal with the many issues that arise due to this situation.
    keywords: anxiety; depression; health; stress
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        item: #3344 of 7819
          id: cord-294427-6eiligyy
      author: Salimi, Ali
       title: The North American Layman's Understanding of COVID-19: Are We Doing Enough?
        date: 2020-07-03
       words: 5701
      flesch: 42
     summary: Satisfaction with public health response was similar among the two groups (χ 2 = 0.255; p = 0.682). No differences were found between the two groups in terms of facemask-wearing (χ 2 = 1.396, p = 0.237) or satisfaction with public health response (χ 2 = 2.221; p = 0.136).
    keywords: covid-19; health; participants; public; risk
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        item: #3345 of 7819
          id: cord-294429-isivkz8b
      author: Grifoni, Alba
       title: Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals
        date: 2020-05-20
       words: 10283
      flesch: 47
     summary: CD4+ T cell responses to spike, the main target of most vaccine efforts, were robust and correlated with the magnitude of the anti-SARS-CoV-2 IgG and IgA titers. CD4 + T cell responses to the remainder of the SARS-CoV-2 orfeome were also detected in 100% of COVID-19 cases (p < 0.0079 vs. unexposed donors non-spike MP, Fig.
    keywords: cases; cd4; cd8; cell; cell responses; cov-2; covid-19; disease; donors; et al; fig; human; responses; sars; specific; spike; t cell
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        item: #3346 of 7819
          id: cord-294438-btuxeq7o
      author: Peng, Ling
       title: Managing patients with cancer in the COVID-19 era
        date: 2020-06-30
       words: 1093
      flesch: 30
     summary: Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study The treatment and outcome of a lung cancer patient infected with SARS-CoV-2 Hepatitis B reactivation during combination chemotherapy for AIDS-related lymphoma is uncommon and does not adversely affect outcome A pneumonia outbreak associated with a new coronavirus of probable bat origin Two things about COVID-19 might need attention SARS-CoV-2 transmission in cancer patients of a tertiary hospital in Wuhan Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China On the use of corticosteroids for 2019-nCoV pneumonia Clinical evidence does not support corticosteroid treatment for 2019-nCoV Many adjuvant patients benefit a great deal more than 5%, as much as 30% in absolute terms in patients with breast cancer at high risk, for example, but there are no data on who to treat or not during the pandemic.
    keywords: cancer; covid-19; patients
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        item: #3347 of 7819
          id: cord-294440-zd0arwmr
      author: Sacco, Guillaume
       title: COVID-19 in seniors: Findings and lessons from mass screening in a nursing home
        date: 2020-06-26
       words: 3988
      flesch: 46
     summary: We were nevertheless able to clarify the symptomatology of COVID-19 residents, and to specify three different clinical profiles of residents with 100% infection within a nursing home affected by the SARS-CoV-2. The pauci-symptomatic expression of COVID-19 in older residents, together with the high prevalence of asymptomatic forms in caregivers, justifies mass screening in nursing homes, possibly prioritizing residents with suggestive combinations of clinical signs including dyspnea, falls, anorexia and/or altered consciousness.
    keywords: covid-19; home; members; nursing; rate; residents; staff; study
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        item: #3348 of 7819
          id: cord-294443-w6p3f5qc
      author: Nadar, Sunil K.
       title: Managing hypertension during the COVID-19 pandemic
        date: 2020-05-14
       words: 1644
      flesch: 40
     summary: The vasoprotective axes of the reninangiotensin system: physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases Clinical implications of SARS-Cov2 interaction with renin angiotensin system A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury Effects of ACE-inhibitors and angiotensin receptor blockers on inflammation European society of Hypertension statement Heart failure society of America joint statement Association of inpatient use of angiotensin converting enzyme inhibitors and angiotensin ii receptor blockers with mortality among patients with hypertension hospitalized with COVID-19 Reninangiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Hypertension and the prothrombotic state Indeed, hospitals have reported a decrease in the number of patients attending emergency departments with myocardial infarctions and cerebrovascular accidents [1, 2] .
    keywords: ace; covid-19; hypertension; inhibitors; patients
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        item: #3349 of 7819
          id: cord-294468-0v4grqa7
      author: Kasilingam, Dharun
       title: Exploring the Growth of COVID‐19 Cases using Exponential Modelling Across 42 Countries and Predicting Signs of Early Containment using Machine Learning
        date: 2020-08-04
       words: 7493
      flesch: 48
     summary: Data associated with the variables were collected from different official sources for a total of 42 counties with respect to COVID-19 infections as on 26 th March 2020. In line with the objectives of the study, classifiers were built based on a set of independent variables to predict if a country that has COVID-19 infections showed early signs of infection containment as a reflection of policy implementations and behaviour changes.
    keywords: article; containment; copyright; coronavirus; countries; covid-19; data; et al; infection; learning; lockdown; outbreak; pandemic; rights; spread
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        item: #3350 of 7819
          id: cord-294501-1nf98mpb
      author: Bonafè, Massimiliano
       title: Inflamm-aging: Why older men are the most susceptible to SARS-CoV-2 complicated outcomes
        date: 2020-05-03
       words: 3754
      flesch: 33
     summary: 25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon Interaction of severe acute respiratory syndrome-coronavirus and NL63 coronavirus spike proteins with angiotensin converting enzyme-2 A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9 High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus, A first step in understanding SARS pathogenesis SARS coronavirus-induced lung injury Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg(9) bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration The discovery of angiotensin-converting enzyme 2 and its role in acute lung injury in mice The clinical pathology of severe acute respiratory syndrome (SARS): a report from China Endothelial cell senescence in aging-related vascular dysfunction Individual variation of the SARS-CoV2 receptor ACE2 gene expression and regulation Comparative genetic analysis of the novel coronavirus (2019-nCoV/ SARS-CoV-2) receptor ACE2 in different populations Inflammaging 2018: an update and a model Senescence-associated secretory phenotypes reveal cellnonautonomous functions of oncogenic RAS and the p53 tumor suppressor Senescence associated macrophages and macroph-aging: Are they pieces of the same puzzle? Age-related M1/M2 phenotype changes in circulating monocytes from healthy/unhealthy individuals Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses Cells exhibiting strong p16 (INK4a) promoter activation in vivo display features of senescence PAI-1 regulation of TGF-beta1-induced alveolar type II cell senescence, SASP secretion, and SASP-mediated activation of alveolar macrophages The telomere world and aging: analytical challenges and future perspectives The hallmarks of aging Sex differences in telomeres and lifespan Changes in the biochemical taste of cytoplasmic and cell-free DNA are major fuels for inflamm-aging Exploiting the telomere machinery to put the brakes on inflamm-aging Shorter leukocyte telomere length is associated with higher risk of infections: a prospective study of 75,309 individuals from the general population DNA methylation age of human tissues and cell types Regeneron, Sanofi to Test Arthritis Drug as Coronavirus Treatment, Wall Street Senolytics in idiopathic pulmonary fibrosis: results from a first-in-human, open-label Senolytics decrease senescent cells in humans: preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease Anti-senescence compounds: a potential nutraceutical approach to healthy aging Repetitive elements in mammalian telomeres suppress bacterial DNA-induced immune activation A suppressive oligodeoxynucleotide expressing TTAGGG motifs modulates cellular energetics through the mTOR signaling pathway Suppressive oligonucleotides inhibit inflammation in a murine model of mechanical ventilator induced lung injury Biological age predictors Where metabolism meets senescence: focus on endothelial cells Measuring biological aging in humans: a quest Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells Circulating miRNAs and miRNA shuttles as biomarkers: perspective trajectories of healthy and unhealthy aging COVID-19 illness in native and immunosuppressed states: a clinical-therapeutic staging proposal We are grateful to Word Designs for text editing (www. silviamodena.com).
    keywords: ace2; age; aging; covid-19; disease; immune; inflamm; inflammation; men; sars
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        item: #3351 of 7819
          id: cord-294517-tqpf95kk
      author: Nimgaonkar, I.
       title: The Age Pattern of the Male- to- Female Ratio in Mortality from COVID-19 Mirrors that of Cardiovascular Disease but not Cancer in the General Population
        date: 2020-07-11
       words: 3174
      flesch: 45
     summary: For the European Countries, data were included for age groups 30 years and above and stratified into 10-year bins, and deaths were combined across the five countries by age group and sex. We found a distinctive pattern in sex ratio of deaths by age, illuminating the nature of the sex effect on death from COVID-19.
    keywords: age; covid-19; deaths; mortality; ratio; sex
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        item: #3352 of 7819
          id: cord-294527-fct2y5vn
      author: Guadarrama-Ortiz, Parménides
       title: Neurological Aspects of SARS-CoV-2 Infection: Mechanisms and Manifestations
        date: 2020-09-04
       words: 8837
      flesch: 29
     summary: (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways Multiple organ infection and the pathogenesis of SARS Pathological study of the 2019 novel coronavirus disease. In this regard, there is increasing preoccupation with the neuroinvasive potential of SARS-CoV-2 due to the observation of neurological manifestations in COVID-19 patients.
    keywords: acute; barré; cells; clinical; coronavirus; cov-2; covid-19; disease; guillain; human; immune; individuals; infection; manifestations; patients; sars; symptoms; syndrome
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        item: #3353 of 7819
          id: cord-294537-wpq1492g
      author: Ritschl, Paul V.
       title: Solid organ transplantation programs facing lack of empiric evidence in the COVID‐19 pandemic: A By‐proxy Society Recommendation Consensus approach
        date: 2020-05-10
       words: 2540
      flesch: 40
     summary: As no consensus guidelines or international recommendations have been published on coronavirus disease 2019 (COVID- 19) and organ transplant, the aim of this study was to offer a consensus-based approach to manage transplant programs until reliable data on risk and benefits of conducting organ transplants in times of a viral pandemic are available. Anticipating a higher-than-average susceptibility of transplant patients for COVID-19, a strong consensus was found for the validity of general preventive and hygienic measures for transplant patients.
    keywords: covid-19; data; paper; patients; sars; transplant; writing
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        item: #3354 of 7819
          id: cord-294555-6q7q8gse
      author: Liang, Ting
       title: Evolution of CT findings in patients with mild COVID-19 pneumonia
        date: 2020-04-15
       words: 3441
      flesch: 51
     summary: key: cord-294555-6q7q8gse authors: Liang, Ting; Liu, Zhe; Wu, Carol C.; Jin, Chao; Zhao, Huifang; Wang, Yan; Wang, Zekun; Li, Fen; Zhou, Jie; Cai, Shubo; Liang, Yukun; Zhou, Heping; Wang, Xibin; Ren, Zhuanqin; Yang, Jian title: Evolution of CT findings in patients with mild COVID-19 pneumonia date: 2020-04-15 journal: To delineate the evolution of CT findings in patients with mild COVID-19 pneumonia.
    keywords: findings; ggo; opacities; patients; pneumonia; severity
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        item: #3355 of 7819
          id: cord-294557-4h0sybiy
      author: Stogiannos, N.
       title: Coronavirus disease 2019 (COVID-19) in the radiology department: What radiographers need to know
        date: 2020-06-04
       words: 6731
      flesch: 41
     summary: A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version) Acute pulmonary embolism associated with COVID-19 pneumonia detected by pulmonary CT angiography Acute pulmonary embolism in COVID-19 patients on CT angiography and relationship with D-Dimer levels Clinical and CT features in pediatric patients with COVID-19 infection: different points of adults CT features of novel coronavirus pneumonia (COVID-19) in children Differences in clinical and imaging presentation of pediatric patients with COVID-19 in comparison to adults Clinical and CT imaging features of the COVID-19 pneumonia: focus on pregnant women and children Medical Imaging plays an important auxiliary role in the diagnosis of Covid-19 patients, mainly those most seriously affected.
    keywords: chest; coronavirus; covid-19; diagnosis; disease; findings; imaging; infection; management; patients; role
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        item: #3356 of 7819
          id: cord-294571-qd0qjo3y
      author: Rothan, Hussin A.
       title: Molecular Aspects of COVID-19 Differential Pathogenesis
        date: 2020-07-06
       words: 3258
      flesch: 35
     summary: key: cord-294571-qd0qjo3y authors: Rothan, Hussin A.; Acharya, Arpan; Reid, St Patrick; Kumar, Mukesh; Byrareddy, Siddappa N. title: Molecular Aspects of COVID-19 Differential Pathogenesis date: 2020-07-06 journal: Pathogens DOI: 10.3390/pathogens9070538 sha: doc_id: 294571 cord_uid: qd0qjo3y In the absence of therapeutic interventions, and a possible vaccine candidate, the spread of COVID-19 disease and associated fatalities are on the rise. There are no effective vaccines or specific antiviral drugs available to manage COVID-19 disease.
    keywords: ace2; children; coronavirus; cov-2; covid-19; disease; expression; patients; sars
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        item: #3357 of 7819
          id: cord-294579-qjga5nmd
      author: Sornsa-ard, Tuanrit
       title: Management of Traumatic Spinal Fracture in the Coronavirus Disease 2019 Situation
        date: 2020-04-24
       words: 876
      flesch: 43
     summary: Such patients may be routinely admitted to the hospital after the possibility of COVID-19 infection is excluded. However, orthopedic trauma patients with an indication for urgency and emergency operative procedures cannot be excluded from COVID-19 infection, since history may be unknown due to unconsciousness or patients who are borderline, unstable, or in a coma (extremis patient).
    keywords: covid-19; infection; patients
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        item: #3358 of 7819
          id: cord-294586-95iwcocn
      author: Kwuimy, C. A. K.
       title: Nonlinear dynamic analysis of an epidemiological model for COVID-19 including public behavior and government action
        date: 2020-07-16
       words: 6087
      flesch: 49
     summary: As can be seen in this table, the values of model parameters changed significantly with transition from uncontrolled to controlled time span owing to strong actions which were imposed to control the disease transmission in South Korea. Also, a p ¼ 10 means that the square error of model infection and removed rates at each end point has ten times more effect on the cost function than the mean square error of all 40 days and this enforces the model to be close to the real data at the end points.
    keywords: action; analysis; covid-19; data; disease; government; individuals; model
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        item: #3359 of 7819
          id: cord-294624-d71za6hi
      author: Kapepula, Paulin M.
       title: Artemisia Spp. Derivatives for COVID-19 Treatment: Anecdotal Use, Political Hype, Treatment Potential, Challenges, and Road Map to Randomized Clinical Trials
        date: 2020-07-23
       words: 2140
      flesch: 34
     summary: As the world desperately searches for new treatments to reduce rates of severe morbidity and mortality from COVID-19, the promotion of new drug discovery building on extracts from traditional medicinal plants should be encouraged. extracts for COVID-19 treatment in low-income countries has led to exaggerated and unproven claims of its efficacy in the absence of a scientific basis or results from clinical trials.
    keywords: annua; artemisia; artemisinin; compounds; covid-19; treatment
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        item: #3360 of 7819
          id: cord-294628-ecg13s7a
      author: Chia, Ming Li
       title: Managing COVID-19 in a Novel, Rapidly Deployable Community Isolation Quarantine Facility
        date: 2020-09-17
       words: 3681
      flesch: 49
     summary: Patients who needed further investigations or were acutely ill were transferred to a general hospital via an ambulance dedicated to patients with COVID-19. This article shares the authors' experience in operating these massive-scale isolation facilities while prioritizing safety for all and ensuring holistic patient care in the face of a public health crisis and lean health care resources.
    keywords: care; covid-19; facility; health; hospital; isolation; monitoring; patients; singapore
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        item: #3361 of 7819
          id: cord-294651-iy0h2pyf
      author: Nasrallah, Ali A.
       title: A large number of COVID-19 interventional clinical trials were registered soon after the pandemic onset: a descriptive analysis
        date: 2020-06-08
       words: 3366
      flesch: 42
     summary: A major limitation of our study is that the pool of COVID-19 registered trials is rapidly growing, hence the data would need to be periodically updated. key: cord-294651-iy0h2pyf authors: Nasrallah, Ali A.; Farran, Sarah H.; Nasrallah, Zainab A.; Chahrour, Mohamad A.; Salhab, Hamza A.; Fares, Mohammad Y.; Khachfe, Hussein H.; Akl, Elie A. title: A large number of COVID-19 interventional clinical trials were registered soon after the pandemic onset: a descriptive analysis date: 2020-06-08 journal: J Clin Epidemiol DOI: 10.1016/j.jclinepi.2020.06.005 sha: doc_id: 294651 cord_uid: iy0h2pyf Abstract Background There is a pressing need for evidence-based interventions to address the devastating clinical and public health effects of the Coronavirus disease 2019 (COVID-19) pandemic.
    keywords: coronavirus; covid-19; evidence; outcomes; patients; results; study; trials
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        item: #3362 of 7819
          id: cord-294672-hcjxcn1n
      author: Namineni, Srinivas
       title: Practice of nitrous oxide inhalation sedation in dentistry during and after the COVID-19 pandemic
        date: 2020-08-27
       words: 619
      flesch: 43
     summary: key: cord-294672-hcjxcn1n authors: Namineni, Srinivas; Mallineni, Sreekanth Kumar title: Practice of nitrous oxide inhalation sedation in dentistry during and after the COVID-19 pandemic date: 2020-08-27 journal: J Dent Anesth Pain Med DOI: 10.17245/jdapm.2020.20.4.261 sha: doc_id: 294672 cord_uid: hcjxcn1n nan The recent outbreak of the coronavirus disease (COVID-19) has attracted global attention to the health care profession. Because it is based on an inhalational route that involves the respiratory tract, lungs, and alveoli for gaseous exchange, respiratory anatomy and physiology have a significant influence on nitrous oxide sedation [3] .
    keywords: covid-19; sedation
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        item: #3363 of 7819
          id: cord-294685-rhhx5gcg
      author: Vasantha Raju, N.
       title: Indian Publications on SARS-CoV-2: A Bibliometric Study of WHO COVID-19 Database
        date: 2020-06-09
       words: 2183
      flesch: 48
     summary: In this regard here in an attempt has been made to look into the Indian contributions to COVID-19 research publications. There were few bibliometric studies on COVID-19 publications pattern worldwide (Dehghanbanadaki et al, 2020; Hossain, 2020; Nasab, & Rahim, 2020) .
    keywords: covid-19; license; preprint; publications; research
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        item: #3364 of 7819
          id: cord-294696-pm6pfeeb
      author: Kunz, Y.
       title: Was sollte ein Urologe zu SARS-Cov-2 wissen? Risikoanalyse für urologische Operationen und Handlungsempfehlungen im klinischen Alltag
        date: 2020-10-13
       words: 3243
      flesch: 36
     summary: Dieser Rauch besteht zu 95 % aus Wasser und 5 % aus Zellmaterial in der Größe von 0,007 -0,31 μm. In der Früherkennung einer drohenden Niereninsuffizienz kommt deshalb einer Urinanalyse eine wichtige Rolle zu
    keywords: als; auch; auf; bei; bereits; coronavirus; cov-2; covid-19; das; der; des; die; durch; eine; für; infection; ist; mit; oder; patienten; patients; sars; und; von; werden; wird
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        item: #3365 of 7819
          id: cord-294700-pb5k21da
      author: Dulek, Daniel E
       title: Multidisciplinary Guidance Regarding the Use of Immunomodulatory Therapies for Acute COVID-19 in Pediatric Patients
        date: 2020-08-18
       words: 14549
      flesch: 30
     summary: A single center experience Rapid and Severe Covid-19 Pneumonia with Severe Acute Chest Syndrome in a Sickle Cell Patient Successfully Treated with Tocilizumab Off-label Use of Tocilizumab in Patients with SARS-CoV-2 Infection Multicenter initial guidance on use of antivirals for children with COVID-19/SARS-CoV-2 COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study Clinical Manifestations and Outcomes of Critically Ill Children and Adolescents with COVID-19 in New York City Post-mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction Autopsy Findings and Venous Thromboembolism in Patients With COVID-19 Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis COVID-19 and its implications for thrombosis and anticoagulation Plasma IP-10 and MCP-3 levels are highly associated with disease severity and predict the progression of COVID-19 Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients Type I IFN immunoprofiling in COVID-19 patients Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19 Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice Targeting the inflammatory cascade with anakinra in moderate to severe COVID-19 pneumonia: case series Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis Tocilizumab for the treatment of severe coronavirus disease 2019 Interleukin-6: A Masterplayer in the Cytokine Network Impaired immune and acute-phase responses in interleukin-6-deficient mice Late interleukin-6 escalates T follicular helper cell responses and controls a chronic viral infection HBV replication is significantly reduced by IL-6 Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis Up-regulation of IL-6 and TNF-alpha induced by SARS-coronavirus spike protein in murine macrophages via NF-kappaB pathway Nucleocapsid protein of SARS-CoV activates interleukin-6 expression through cellular transcription factor NF-kappaB Lack of innate interferon responses during SARS coronavirus infection in a vaccination and reinfection ferret model Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding Tocilizumab for treatment of mechanically ventilated patients with COVID-19 Tocilizumab in patients with severe COVID-19: a retrospective cohort study Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized COVID-19 Patients: Survival and Clinical Outcomes Pilot prospective open, single-arm multicentre study on offlabel use of tocilizumab in patients with severe COVID-19 Efficacy and safety of tocilizumab in severe COVID-19 patients: a single-centre retrospective cohort study Effective treatment of severe COVID-19 patients with tocilizumab Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: A single center study of 100 patients in Pneumatosis Intestinalis and Intestinal Perforation in a Transaminase Levels and Hepatic Events During Tocilizumab Treatment: Pooled Analysis of Long-Term Clinical Trial Safety Data in Rheumatoid Arthritis Letter to the Editor: Acute hypertriglyceridemia in patients with COVID-19 receiving tocilizumab Anakinra for severe forms of COVID-19: a cohort study Canakinumab in a subgroup of patients with COVID-19 Critical regulation of early Th17 cell differentiation by interleukin-1 signaling Interleukin (IL) 1beta induction of IL-6 is mediated by a novel phosphatidylinositol 3-kinase-dependent AKT/IkappaB kinase alpha pathway targeting activator protein-1 Anakinra Therapy for Non-cancer Inflammatory Diseases Rilonacept and canakinumab European Group Of Clinical I. Long-term safety and maintenance of clinical improvement following treatment with anakinra (recombinant human interleukin-1 receptor antagonist) in patients with rheumatoid arthritis: extension phase of a randomized, double-blind, placebo-controlled trial A multicentre, double blind, randomised, placebo controlled trial of anakinra (Kineret), a recombinant interleukin 1 receptor antagonist, in patients with rheumatoid arthritis treated with background methotrexate Randomized, double-blind, placebo-controlled trial of the efficacy and safety of rilonacept in the treatment of systemic juvenile idiopathic arthritis Efficacy and safety of rilonacept Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies Sustained remission of symptoms and improved health-related quality of life in patients with cryopyrin-associated periodic syndrome treated with canakinumab: results of a double-blind placebo-controlled randomized withdrawal study Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes Highlights of Prescribing Information Critical Assessment of Pharmacokinetic Drug-Drug Interaction Potential of Tofacitinib, Baricitinib and Upadacitinib, the Three Approved Janus Kinase Inhibitors for Rheumatoid Arthritis Treatment The convalescent sera option for containing COVID-19 Use of convalescent plasma therapy in SARS patients in Hong Kong Retrospective comparison of convalescent plasma with continuing high-dose methylprednisolone treatment in SARS patients Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma Treatment With Convalescent Plasma for Critically Ill Patients With SARS-CoV-2 Infection Effectiveness of convalescent plasma therapy in severe COVID-19 patients Use of Convalescent Plasma Therapy in Two COVID-19 Patients with Acute Respiratory Distress Syndrome in Korea Treatment with convalescent plasma for COVID-19 patients in Wuhan Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19: A Randomized Clinical Trial Profile of IgG and IgM antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Antibody responses to SARS-CoV-2 in patients with COVID-19 Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-19 Effect of Convalescent Plasma Therapy on Viral Shedding and Survival in COVID-19 Patients First case of convalescent plasma transfusion in a child with COVID-19-associated severe aplastic anemia Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry Administration FaD Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection Passively acquired antibodies suppress humoral but not cell-mediated immunity in mice immunized with live attenuated respiratory syncytial virus vaccines Serum and nasal-wash immunoglobulin G and A antibody response of infants and children to respiratory syncytial virus F and G glycoproteins following primary infection Deployment of convalescent plasma for the prevention and treatment of COVID-19 Currently available intravenous immunoglobulin contains antibodies reacting against severe acute respiratory syndrome coronavirus 2 antigens Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor Preparations of intravenous immunoglobulins diminish the number and proinflammatory response of CD14+CD16++ monocytes in common variable immunodeficiency (CVID) patients Intravenous gammaglobulin inhibits encephalitogenic potential of pathogenic T cells and interferes with their trafficking to the central nervous system, implicating sphingosine-1 phosphate receptor 1-mammalian target of rapamycin axis Update on the use of immunoglobulin in human disease: A review of evidence Interleukin 1 Receptor Antagonist Anakinra, Intravenous Immunoglobulin, and Corticosteroids in the Management of Critically Ill Adult Patients With Hemophagocytic Lymphohistiocytosis Thrombocytopenia in patients with severe acute respiratory syndrome (review) Incidence and Outcome of Severe and Nonsevere Thrombocytopenia Associated With Zika Virus Infection-Puerto Rico Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis Macrophage Activation Syndrome High-Dose Intravenous Immunoglobulin as a Therapeutic Option for Deteriorating Patients With Coronavirus Disease Type I interferons in infectious disease Interferon-lambda orchestrates innate and adaptive mucosal immune responses COVID-19 and emerging viral infections: The case for interferon lambda A randomized phase 2b study of peginterferon lambda-1a for the treatment of chronic HCV infection 96weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection Korean Association for the Study of the L. KASL clinical practice guidelines for management of chronic hepatitis B
    keywords: acute; anakinra; children; clinical; coronavirus; cov-2; covid-19; covid-19 patients; cytokine; data; disease; evidence; infection; inflammatory; p t; patients; pediatric; sars; studies; syndrome; therapy; tocilizumab; treatment; use
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        item: #3366 of 7819
          id: cord-294736-ji4jz3h6
      author: Beşler, Muhammed Said
       title: Acute myocarditis associated with COVID-19 infection()
        date: 2020-06-02
       words: 301
      flesch: 34
     summary: This case showed that acute myocarditis can be the initial presentation of patients with COVID-19 infection. key: cord-294736-ji4jz3h6 authors: Beşler, Muhammed Said; Arslan, Halil title: Acute myocarditis associated with COVID-19 infection() date: 2020-06-02 journal: Am J Emerg Med DOI: 10.1016/j.ajem.2020.05.100 sha: doc_id: 294736 cord_uid: ji4jz3h6 We present the case of a 20-year-old male patient without previous history of cardiovascular disease who was admitted to our hospital with a new onset febrile sensation and chest pain.
    keywords: covid-19; myocarditis
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        item: #3367 of 7819
          id: cord-294768-bs6thjw2
      author: Alonso-Fernández, Alberto
       title: Prevalence of pulmonary embolism in patients with COVID-19 pneumonia and high D-dimer values: A prospective study
        date: 2020-08-25
       words: 4656
      flesch: 43
     summary: D-dimer, platelet count, and, C reactive protein values were significantly higher among PE patients. The proportion of patients with PE diagnosed during the first days (when laboratory data was obtained by protocol) was higher (66.7%) than the proportion of PE patients diagnosed during follow-up (when laboratory data was obtained at the discretion of the clinician) (42.9%).
    keywords: covid-19; dimer; patients; pneumonia; pulmonary; risk; study; values
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        item: #3368 of 7819
          id: cord-294772-nma7w7of
      author: de Oliveira Collet, Giulia
       title: COVID-19 pandemic and pediatric dentistry: fear, eating habits and parent’s oral health perceptions
        date: 2020-09-15
       words: 3583
      flesch: 55
     summary: How does the quarantine resulting from COVID-19 impact dental appointments and patient anxiety levels? Biological and social aspects of Coronavirus Disease 2019 (COVID-19) related to oral health Lockdown on Lifestyle Behaviors in Children with Obesity Living in High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2 Parents' Stress and Children's Psychological Problems in Families Facing the COVID-19 Outbreak in Italy A Global Survey on the Impact of COVID-19 on Urological Services Summary of probable SARS cases with onset of illness from 1 MERS situation update Q&A on coronaviruses (COVID-19) Were any of your children (0-12 years old) undergoing dental treatment before the pandemic? Association was found among parents/caregivers' willingness to take their children to dental appointments, fear level (p<0.001), and the local number of COVID-19 cases (p<0.001) ( Table 4) .
    keywords: care; children; covid-19; fear; health; pandemic; parents
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        item: #3369 of 7819
          id: cord-294788-9usyb1nn
      author: Baek, Woong Kee
       title: A Comprehensive Review of Severe Acute Respiratory Syndrome Coronavirus 2
        date: 2020-05-03
       words: 4478
      flesch: 41
     summary: Patients with mild symptoms presented with an elevation of cytokines within the reference ranges, while severe patients showed markedly elevated levels [19] . The pathophysiology behind the peripheral leukopenia in severe patients is not fully understood.
    keywords: cells; coronavirus; cov-2; covid-19; disease; infection; patients; sars; symptoms; syndrome
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        item: #3370 of 7819
          id: cord-294789-07hto8qn
      author: Schoch-Spana, Monica
       title: The public’s role in COVID-19 vaccination: human-centered recommendations to enhance pandemic vaccine awareness, access, and acceptance in the United States
        date: 2020-10-29
       words: 5812
      flesch: 33
     summary: A combination of literature reviews on vaccination, pandemic planning, and health crisis communication; an assessment of current news and social media trends regarding COVID-19 vaccines; and key informant interviews with each working group member focusing on their respective expertise formed the basis of the research presented in this article. In the case of SARS-CoV-2 vaccination, for instance, while an NIH Funding Opportunity Award that could support research on human factors related to vaccine acceptance was made possible in June 2020, the earliest project start date is September 2021, a full nine months after Operation Warp Speed plans for COVID-19 vaccines to become available [21] .
    keywords: communication; community; cov-2; covid-19; group; health; human; pandemic; populations; public; research; safety; sars; vaccination; vaccine
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        item: #3371 of 7819
          id: cord-294792-m6phbueb
      author: Pascual-Prieto, Javier
       title: Epidemia covid-19: ¿debe el oftalmólogo estar alerta ante las paresias oculomotoras?
        date: 2020-05-23
       words: 511
      flesch: 34
     summary: Dadas las circunstancias actuales, carecemos de otras pruebas de imagen como la resonancia magnética, que pudiere haber revelado inflamación nerviosa en el contexto de la infección vírica 4 . Sin embargo, otros grupos han publicado casos en los que teorizan una etiología para-infecciosa o simultánea para este mismo síndrome 5, 6 Como ya advierten Gutiérrez-Ortiz et al., es importante pensar que la relación entre las oftalmoparesias y la enfermedad por COVID-19 puede haber sido solo coincidental 3 Otros autores sugieren que en los pacientes más graves se desencadenan sucesos de hiperinflamación que pueden provocar fenómenos de inmunotrombosis en la microvasculatura.
    keywords: con; covid-19; que
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        item: #3372 of 7819
          id: cord-294800-akr4f5p8
      author: Kabir, Md. Tanvir
       title: nCOVID-19 Pandemic: From Molecular Pathogenesis to Potential Investigational Therapeutics
        date: 2020-07-10
       words: 14110
      flesch: 33
     summary: Recently, it has been observed that nCOVID-19 might predispose to both arterial and venous thromboembolic disease because of immobilization, hypoxia, inflammation, and diffuse intravascular coagulation Guan et al., 2020; Klok et al., 2020; Wang et al., 2020a; Zhou et al., 2020) . Also, the derivatives of teicoplanin including telavancin, dalbavancin, and oritavancin, were also found to block the entry of SARS, MERS, and Ebola viruses (Zhou et al., 2016) .
    keywords: acute; antiviral; cells; coronavirus; cov-2; day; disease; drug; et al; host; human; individuals; infection; influenza; mers; ncovid-19; novel; patients; pneumonia; protein; response; sars; studies; study; syndrome; transmission; treatment; use; vitamin
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        item: #3373 of 7819
          id: cord-294810-mq9vjnro
      author: Huang, Qiong
       title: Clinical characteristics and drug therapies in patients with the common-type coronavirus disease 2019 in Hunan, China
        date: 2020-05-14
       words: 3441
      flesch: 49
     summary: Severe COVID-19 patients present with any of the following: (1) shortness of breath, plus respiratory rate ≥ 30 breaths/min, (2) in resting state, oxygen saturation (SpO2) ≤ 93%, and 3) arterial partial pressure of oxygen (PaO2)/Fraction of inspiration oxygen (FiO2) ≤ 300 mmHg. Objective The study was aimed to describe the clinical characteristics, laboratory parameters, and therapeutic methods of COVID-19 patients in Hunan, China.
    keywords: coronavirus; covid-19; disease; patients; study; symptoms; treatment; type; wuhan
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        item: #3374 of 7819
          id: cord-294831-pem059zk
      author: Zhang, Ling-Pu
       title: Focus on a 2019-novel coronavirus (SARS-CoV-2)
        date: 2020-06-11
       words: 6212
      flesch: 49
     summary: SARS-CoV-2 envelope (E) protein, matrix protein, accessory proteins p6 and p8, nonstructural protein 7 (nsp7), and nsp13 are homologous with those of SARS virus SARS-CoV-2 has 82% nucleotide identity with human SARS-CoV and 96% nucleotide identity with bat SARS coronavirus (SARSr-CoV-RaTG13).
    keywords: antiviral; china; coronavirus; cov-2; covid-19; infection; mers; ncov; novel; patients; pneumonia; rate; sars; study
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        item: #3375 of 7819
          id: cord-294840-yo7b2v3k
      author: Milner, Adrienne
       title: We Need to Talk About Racism—In All of Its Forms—To Understand COVID-19 Disparities
        date: 2020-09-25
       words: 3721
      flesch: 36
     summary: Racism is an essential factor to understand racial health disparities in infection and mortality due to COVID-19 and must be thoroughly integrated into any successful public health response. 39 Health Equity Implications Determining the manner in which different types of racism shape health disparities is essential for counteracting the effects of modern racist ideology and promoting health equity.
    keywords: americans; color; covid-19; disparities; health; racial; racism; white
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        item: #3376 of 7819
          id: cord-294854-rvrgcugn
      author: Hu, Biying
       title: The cytokine storm and COVID‐19
        date: 2020-06-27
       words: 2788
      flesch: 33
     summary: Potential for global spread of a novel coronavirus from China Clinical features of patients infected with 2019 novel coronavirus in Wuhan An interferon-gamma-related cytokine storm in SARS patients Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis COVID-19: consider cytokine storm syndromes and immunosuppression Chapter Eight -Hosts and Sources of Endemic Human Coronaviruses Coronaviridae Study Group of the International Committee on Taxonomy of Viruses. Pathological alterations in COVID-19 patients include pulmonary edema, diffuse alveolar injury with the formation of hyaline membranes, the presence of reactive type II pneumocyte hyperplasia, proteinaceous aggregates, fibrinous Accepted Article exudates, monocytes and macrophages within alveolar spaces, and inflammatory infiltration of interstitial mononuclear cells [25] [26]
    keywords: acute; coronavirus; cov-2; covid-19; cytokine; patients; sars; storm; syndrome
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        item: #3377 of 7819
          id: cord-294861-inlaz4od
      author: Liu, Chen
       title: Six Gynecological Cancer Patients Infected With SARS-CoV-2 After Surgery or Radio-/Chemo-Therapy Treatment: Case Series
        date: 2020-09-15
       words: 3244
      flesch: 47
     summary: We noticed that cancer patients, with a fragile physical state and a higher chance of exposure during routine follow-up, might require special attention at this stage. Thus, more individualized clinical management should be customized to cope with the complexities of the virus in cancer patients.
    keywords: cancer; case; covid-19; patients; sars; treatment
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        item: #3378 of 7819
          id: cord-294871-bqw48zi5
      author: Wambier, Carlos Gustavo
       title: Androgenetic alopecia in COVID-19: compared to age-matched epidemiologic studies and hospital outcomes with or without the Gabrin sign
        date: 2020-07-29
       words: 641
      flesch: 40
     summary: 5 It is remarkable that severe outcomes 81 such as requirement for ventilator and/or fatalities have occurred in men with this phenotype 82 without other known co-morbidities at younger age groups, such as 35-45 years. Finally, severe AGA, 78 (HNS=3-7) -the Gabrin Sign -is an objective phenotype, which reflects the individual androgen 79 sensitivity throughout decades of life.
    keywords: covid-19; men
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        item: #3379 of 7819
          id: cord-294900-pmrffqe3
      author: Arbel, Yuval
       title: Can Increased Recovery Rates from Coronavirus be explained by Prevalence of ADHD? An Analysis at the US Statewide Level
        date: 2020-09-21
       words: 1490
      flesch: 45
     summary: Based on information from 2011 regarding the prevalence of ADHD across the US by state, findings suggest that, while there are no correlations between ADHD and population size, infection and mortality rates from coronavirus, recovery rates (recovery-population ratio) rise with the prevalence of ADHD. Findings suggest that, while contrary to previous studies, there are no correlations between ADHD and population size, and infection and mortality rates from coronavirus, recovery rates (recovery-population ratio) rise with the prevalence of ADHD.
    keywords: adhd; coronavirus; population; recovery
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        item: #3380 of 7819
          id: cord-294906-1m4h116m
      author: Jarmoliński, Tomasz
       title: SARS‐CoV‐2 viral clearance during bone marrow aplasia after allogeneic hematopoietic stem cell transplantation – a case report
        date: 2020-09-18
       words: 1484
      flesch: 41
     summary: Early and repeated testing for SARS‐CoV‐2 in posttransplant patients with concomitant infection mitigation strategies should be considered in children after HSCT who develop fever, respiratory symptoms and perhaps gastrointestinal symptoms to control the spread of COVID‐19 both in patients and healthcare workers in hospital environments. Due to posttransplant patient isolation, no imaging studies were performed.
    keywords: article; copyright; covid-19; patient; rights
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        item: #3381 of 7819
          id: cord-294910-gnc04ax1
      author: Nogueira, Paulo Jorge
       title: The Role of Health Preconditions on COVID-19 Deaths in Portugal: Evidence from Surveillance Data of the First 20293 Infection Cases
        date: 2020-07-24
       words: 4943
      flesch: 36
     summary: The results of the present study registered potential different pathophysiological mechanisms for COVID-19 mortality, suggesting the need for a team approach between different medical specialties in order to maximize the probabilities of recovery for COVID-19 patients. Patients: Results of the SARS-RAS Study of the Italian Society of Hypertension National age and coresidence patterns shape COVID-19 vulnerability Acute kidney injury is associated with the mortality of coronavirus disease 2019 Determinants of blood pH in health and disease Is the kidney a target of SARS-CoV-2? Kidney disease is associated with in-hospital death of patients with COVID-19 Impact of Cerebrovascular and Cardiovascular Diseases on Mortality and Severity of COVID-19-Systematic Review, Meta-analysis, and Meta-regression Issues of Cardiovascular Risk Management in People With Diabetes in the COVID-19 Era North American COVID-19 ST-segment elevation myocardial infarction (NACMI) registry: Rationale, design, and implications Takotsubo syndrome during SARS-CoV-2 pneumonia: A possible cardiovascular complication Myocardial injury determination improves risk stratification and predicts mortality in COVID-19 patients The Heart in COVID19: Primary Target or Secondary Bystander? COVID 19 and heart failure: From infection to inflammation and angiotensin II stimulation.
    keywords: age; cases; covid-19; disease; mortality; patients; preconditions; risk; study
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        item: #3382 of 7819
          id: cord-294912-xl0wzi16
      author: Alteri, Claudia
       title: Detection and quantification of SARS-CoV-2 by droplet digital PCR in real-time PCR negative nasopharyngeal swabs from suspected COVID-19 patients
        date: 2020-09-08
       words: 3634
      flesch: 38
     summary: Of note, a severe COVID-19 manifestation characterized 14 of the 19 patients with a ddPCR confirmed SARS--CoV-2 infection (73.7%, S1 Table) . In order to further confirm the performance of the ddPCR-based assay, IgG against SARS--CoV-2 were tested by using a commercial Chemiluminescent microparticle immunoassay IgG against SARS-CoV-2 (https://www.corelaboratory.abbott/us/en/offerings/segments/ infectious-disease/sars-cov-2, sensitivity:99.9% specificity:100%)
    keywords: copies; cov-2; covid-19; ddpcr; patients; rtpcr; samples; sars
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        item: #3383 of 7819
          id: cord-294916-xc9ozxyn
      author: Oehmen, Josef
       title: Risk, uncertainty, ignorance and myopia: Their managerial implications for B2B firms
        date: 2020-07-31
       words: 8489
      flesch: 38
     summary: Risk, uncertainty and profitBoston, MA: Houghton Mifflin Company Obtaining Reliability and Safety Assessments on the Basis of Non-Probabilistic Methods Unskilled and unaware of it: How difficulties in recognizing one's own incompetence lead to inflated self-assessments The rational choice of not applying project risk management in information technology projects Bridging the risk gap: The failure of risk management in information systems projects Deliberate ignorance in project risk management When we don't know the costs or the benefits: Adaptive strategies for abating climate change A new decision sciences for complex systems Anheuser-Busch and Distilleries Race to Make Hand Sanitizer Amid Coronavirus Pandemic As we are currently experiencing with the COVID-19 pandemic, we do not sufficiently leverage the rich toolset that risk management offers to prepare for and mitigate the resulting uncertainty.
    keywords: aven; challenges; covid-19; decision; future; health; ignorance; making; management; myopia; pandemic; ppe; probability; resilience; risk; risk management; uncertainty
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        item: #3384 of 7819
          id: cord-294924-5u2tfyd0
      author: Ali, Nurshad
       title: Is SARS-CoV-2 associated with liver dysfunction in COVID-19 patients?
        date: 2020-05-21
       words: 1237
      flesch: 37
     summary: A high prevalence of liver test abnormalities in some studies, suggesting that liver injury in COVID-19 patients might be directly caused by the SARS-CoV-2 infection of liver cells (Cai et al. 2020; Zhang et al. 2020) . Moreover, the use of antibiotics showed a significant association with liver injury in COVID-19 patients in the multivariate regression model; however, the association was not significant when the inverse probability weighting model was applied (Cai et al. 2020 ).
    keywords: liver; patients
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        item: #3385 of 7819
          id: cord-294933-oc2glu4a
      author: Cinesi Gómez, César
       title: Clinical consensus recommendations regarding non-invasive respiratory support in the adult patient with acute respiratory failure secondary to SARS-CoV-2 infection
        date: 2020-06-19
       words: 5647
      flesch: 39
     summary: An official clinical practice guideline of the Severe acute respiratory syndrome (SARS) ---lessons for future pandemics MERS transmission and risk factors: a systematic review Clinical practice guidelines by the Infectious Diseases Society of America: 2018 update on diagnosis, treatment, chemoprophylaxis, and institutional outbreak management of seasonal influenza Highlights in acute respiratory failure High-flow nasal cannula oxygen therapy is superior to conventional oxygen therapy but not to noninvasive mechanical ventilation on intubation rate: a systematic review and meta-analysis Current evidence for the effectiveness of heated and humidified high flow nasal cannula supportive therapy in adult patients with respiratory failure British Thoracic Society/Intensive Care Society Guideline for the ventilatory management of acute hypercapnic respiratory failure in adults Extracorporeal membrane oxygenation for critically ill adults Noninvasive ventilation in acute hypercapnic respiratory failure Effectiveness of noninvasive positive pressure ventilation in the treatment of acute respiratory failure in severe acute respiratory syndrome Noninvasive mechanical ventilation in severe pneumonia due to H1N1 virus Pandemic 2009 influenza A in Argentina: a study of 337 patients on mechanical ventilation Early non-invasive ventilation treatment for severe influenza pneumonia Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure Clinical management of severe acute respiratory infection when novel coronavirus (2019-nCoV) infection is suspected Severe SARS-CoV-2 infections: practical considerations and management strategy for intensivists. A fundamental element in the management of ARF in COVID-19 patients in monitoring ---preferably of a non-invasive nature.
    keywords: covid-19; disease; failure; flow; healthcare; infection; management; nasal; nimv; oxygen; patients; sars; therapy; use; ventilation
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        item: #3386 of 7819
          id: cord-294948-o8mn0w7y
      author: Gathungu, D. K.
       title: Modeling the Effects of Non-PharmaceuticalInterventions on COVID-19 Spread in Kenya
        date: 2020-05-20
       words: 3970
      flesch: 50
     summary: In order to simulate and predict infection cases from the model, we use the framework developed by [7] . In the quest to determine the level of preparedness to curb spread of COVID-19, it is important to predict future numbers of daily infection cases and cumulative infections.
    keywords: cases; covid-19; infections; license; model; population; preprint
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        item: #3387 of 7819
          id: cord-294958-4982wy81
      author: Hunt, Madison
       title: A Case of COVID-19 Pneumonia in a Young Male with Full Body Rash as a Presenting Symptom
        date: 2020-03-28
       words: 615
      flesch: 51
     summary: Rash has only been rarely reported in COVID-19 patients, and has not been previously described. We describe a case of COVID-19 pneumonia requiring hospitalization that presented with fever and extensive rash as the primary presenting symptoms.
    keywords: covid-19; rash
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        item: #3388 of 7819
          id: cord-294963-h68fy5sy
      author: Al-Zaman, M. S.
       title: Bibliometric analysis of COVID-19 literature
        date: 2020-07-19
       words: 3390
      flesch: 58
     summary: 1101 Mahase (15 papers), and J. A. Al-Tawfiq (14 papers) were the top three authors in terms of published papers. Having many positive contributions, this trend has some drawbacks since many published papers are found as unsubstantial.
    keywords: analysis; covid-19; papers; publications
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        item: #3389 of 7819
          id: cord-294966-3jolt83r
      author: Joensen, L. E.
       title: Diabetes and COVID‐19: psychosocial consequences of the COVID‐19 pandemic in people with diabetes in Denmark—what characterizes people with high levels of COVID‐19‐related worries?
        date: 2020-05-29
       words: 4027
      flesch: 47
     summary: • Female gender, type 1 diabetes, diabetes complications, isolation, loneliness, high diabetes distress and behaviour changes were associated with being more worried about COVID-19 and diabetes. Our findings also showed that experiencing high diabetes distress and feeling lonely were related to experiencing COVID-19specific worries.
    keywords: covid-19; diabetes; health; pandemic; people; support; type; worries
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        item: #3390 of 7819
          id: cord-294969-57xgqf2g
      author: Green, Bart N.
       title: Rapid Deployment of Chiropractic Telehealth at 2 Worksite Health Centers in Response to the COVID-19 Pandemic: Observations from the Field
        date: 2020-06-11
       words: 5988
      flesch: 49
     summary: WSHCs are clinics where employees, and sometimes the dependents of employees, have access to a variety of health care services at or near the workplace of the employees. This is a descriptive report of how we transitioned from in-clinic to telehealth care during the COVID-19 pandemic.
    keywords: care; chiropractic; clinic; covid-19; home; patient; rtvc; services; telehealth; time; use; video
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        item: #3391 of 7819
          id: cord-295029-zki5ac2g
      author: Pena, Robert C.F.
       title: In Reply to the Letter to the Editor Regarding “Coronavirus Neurosurgical/Head and Neck Drape to Prevent Aerosolization of Coronavirus Disease 2019 (COVID-19): The Lenox Hill Hospital/Northwell Health Solution”
        date: 2020-11-03
       words: 1650
      flesch: 24
     summary: HIV-1 aerosolization, for example, has been shown to occur at slower drill speeds (30,000 rpm), meaning a precautionary reduction in rotational speed likely does not protect against viral aerosol transmission. Even more, the cancellation of elective surgical procedures may protect surgical staff to a point, but they still incur substantial risk in the performance of emergent, nondelayable care.
    keywords: aerosol; covid-19; procedures; sars; transmission
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        item: #3392 of 7819
          id: cord-295041-5vpawtef
      author: Jakhmola, Shweta
       title: SARS-CoV-2, an Underestimated Pathogen of the Nervous System
        date: 2020-09-28
       words: 5028
      flesch: 35
     summary: Cochrane Database Syst Rev SARS-CoV-2: recent reports on antiviral therapies based on lopinavir/ritonavir, darunavir/ umifenovir, hydroxychloroquine, remdesivir, favipiravir and other drugs for the treatment of the new coronavirus Amantadine disrupts lysosomal gene expression: a hypothesis for COVID19 treatment TH17 responses in cytokine storm of COVID-19: an emerging target of JAK2 inhibitor Fedratinib Proinflammatory cytokines and chemokines in humans with Japanese encephalitis COVID-19 in a MS patient treated with ocrelizumab: does immunosuppression have a protective role? Neuroinflammation during RNA viral infections Inflammatory activation of microglia and astrocytes in manganese neurotoxicity Microglia in infectious diseases of the central nervous system Astrocytes maintain glutamate homeostasis in the CNS by controlling the balance between glutamate uptake and release Vitamin D receptor activation regulates microglia polarization and oxidative stress in spontaneously hypertensive rats and angiotensin IIexposed microglial cells: role of renin-angiotensin system Within the brain: the renin angiotensin system Coronavirus neurovirulence correlates with the ability of the virus to induce proinflammatory cytokine signals from astrocytes and microglia Hematological findings in SARS patients and possible mechanisms (review) Activation of human monocytes after infection by human coronavirus 229E Understanding SARS-CoV-2-Mediated inflammatory responses: from mechanisms to potential therapeutic tools COVID-19: consider cytokine storm syndromes and immunosuppression Angiotensin-converting enzyme 2: central regulator for cardiovascular function ACE2 in brain physiology and pathophysiology: evidence from transgenic animal models Inhibitory interneurons regulate temporal precision and correlations in cortical circuits Angiotensin II regulation of angiotensin-converting enzymes in spontaneously hypertensive rat primary astrocyte cultures SARS-CoV2 entry and spread in the lymphatic drainage system of the brain Central nervous system involvement by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neurotropic mechanisms Can the enteric nervous system be an alternative entrance door in SARS-CoV2 neuroinvasion? SARS-CoV-2 productively infects human gut enterocytes The pivotal link between ACE2 deficiency and SARS-CoV-2 infection SARS-CoV-2: olfaction, brain infection, and the urgent need for clinical samples allowing earlier virus detection The olfactory bulb: an immunosensory effector organ during neurotropic viral infections Respiratory barrier as a safeguard and regulator of defense against influenza A virus and Single-cell analysis of olfactory neurogenesis and differentiation in adult humans Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV Novel dynamics of human mucociliary differentiation revealed by single-cell RNA sequencing of nasal epithelial cultures Hierarchical deconstruction of mouse olfactory sensory neurons: from whole mucosa to single-cell RNA-seq A multibasic cleavage site in the spike protein of SARS-CoV-2 is essential for infection of human lung cells Furin at the cutting edge: from protein traffic to embryogenesis and disease Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations T helper cell 17 (Th17)-mediated cytokine storm, evident in virus infections, is seen in COVID-19 with neurological manifestations (Fig. 1b)
    keywords: brain; cells; cns; coronavirus; cov-2; covid-19; infection; olfactory; patients; sars; studies; system; virus; viruses
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        item: #3393 of 7819
          id: cord-295051-upyar7en
      author: Ahmadian, Elham
       title: Covid‐19 and kidney injury: Pathophysiology and molecular mechanisms
        date: 2020-10-06
       words: 4866
      flesch: 38
     summary: In addition, Covid-19 patients have shown similar patterns to SARS cases in the prevalence rate of AKI; a retroperspective study reported 6% of SARS patients to suffer also from F I G U R E 2 Direct effects of SARS-CoV-2 on kidney injury. ACE-2 and transmembrane protease, serine 2 (TMPRSS2) genes are expressed in kidney cells as much as in lung, small intestine and oesophagus; supporting their role as profound targets of SARS-CoV-2.
    keywords: ace2; acute; aki; angiotensin; cells; coronavirus; cov-2; covid-19; injury; kidney; patients; sars
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        item: #3394 of 7819
          id: cord-295058-c88fq1de
      author: Ardila, Alfredo
       title: Executive dysfunction in COVID-19 patients
        date: 2020-07-22
       words: 652
      flesch: 18
     summary: The elusive nature of executive functions: a review of our current understanding Principles of frontal lobe function Dysexecutive syndromes Executive Dysfunction in Subcortical Diseases Executive Dysfunctions in Autism Spectrum Disorders Executive function and developmental disorders: the flip side of the coin Predictors of decision-making on the Iowa Gambling Task: Independent effects of lifetime history of substance use disorders and performance on the Trail Making Test Executive dysfunction in substance dependent individuals during drug use and abstinence: an examination of the behavioral, cognitive and emotional correlates of addiction COVID-19 Pandemic: A Neurological Perspective Neurologic features in severe SARS-CoV-2 infection Nervous system damage after COVID-19 infection: presence or absence Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study COVID-19-associated acute hemorrhagic necrotizing encephalopathy: CT and MRI features Neurological complications of coronavirus disease (COVID-19): encephalopathy. The previous information suggests than in a significant number of cases COVID-19 infection may be associated with an executive dysfunction syndrome.
    keywords: covid-19; executive; syndrome
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        item: #3395 of 7819
          id: cord-295066-76se8mxq
      author: Botti, Fiorenzo
       title: URGENT SURGERY FOR INFLAMMATORY BOWEL DISEASES DURING THE COVID-19 OUTBREAK IN A HIGH INCIDENCE AREA - EXPERIENCE FROM A HIGH-VOLUME CENTRE
        date: 2020-08-31
       words: 1731
      flesch: 38
     summary: [5] We hereby report our experience on surgical management of IBD patients as a high-volume centre located in a high-incidence region for COVID-19. [4] As a tertiary referral centre for the surgical management of IBD patients, it was important to clearly define which complicated IBD cases were to be operated, by taking into account several variables including disease severity and quality of life, presence of comorbidities, feasibility of an alternative procedure.
    keywords: covid-19; ibd; patients; surgery
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        item: #3396 of 7819
          id: cord-295068-2q3ts04l
      author: Liu, Yang
       title: Prominent coagulation disorder is closely related to inflammatory response and could be as a prognostic indicator for ICU patients with COVID-19
        date: 2020-08-06
       words: 3362
      flesch: 41
     summary: However, an in-depth study of blood coagulation abnormality, influencing factors, the relationship between blood coagulation and inflammation reaction, and the impact on prognosis is still needed. Several reports elucidated the abnormalities of blood coagulation in patients with COVID-19
    keywords: blood; coagulation; covid-19; fdp; inflammation; level; patients
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        item: #3397 of 7819
          id: cord-295082-z29567vc
      author: Belingheri, Michael
       title: Effects of COVID‐19 lockdown on epidemic diseases of childhood
        date: 2020-07-11
       words: 169
      flesch: 32
     summary: Beyond the assistance: additional exposure situations to COVID-19 for healthcare workers Working schedule, sleep quality, and susceptibility to COVID-19 in healthcare workers COVID-19: health prevention and control in non-healthcare settings Epidemiological evidence for association between higher influenza vaccine uptake in the elderly and lower COVID-19 deaths in Italy Pattern of emergency department referral during the COVID-19 outbreak in Italy COVID-19 epidemic indeed led to a decreasing flow to the ED, due to a common fear of being infected during ED in-stay.
    keywords: covid-19
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        item: #3398 of 7819
          id: cord-295107-67tts3oj
      author: Ozturk, Ayperi
       title: Bronchoscopic procedures during COVID‐19 pandemic: Experiences in Turkey
        date: 2020-08-11
       words: 2145
      flesch: 42
     summary: Thus, the minimization of transmission from patients with COVID-19 to other patients or health care workers was ensured. Malignancy was diagnosed in 59 (79.7%), 12 (50%), and 4 (25%) patients who underwent EBUS, interventional procedures, and fibreoptic bronchoscopy, respectively.
    keywords: bronchoscopy; covid-19; health; pandemic; patients; procedures
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        item: #3399 of 7819
          id: cord-295113-2c4o4hd6
      author: Enwemeka, Chukuka Samuel
       title: Light as a potential treatment for pandemic coronavirus infections: A perspective
        date: 2020-05-01
       words: 4445
      flesch: 38
     summary: blue light Blue 470 nm light suppresses the growth of Salmonella enterica and Methicillin-resistant Staphylococcus aureus (MRSA) in vitro Blue laser inhibits bacterial growth of Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa Helicobacter pylori accumulates photoactive porphyrins and is killed by visible light Enhanced inactivation of Escherichia coli and Listeria monocytogenes by exposure to 405 nm light under sub-lethal temperature, salt and acid stress conditions The opportunistic human pathogen Acinetobacter baumannii senses and responds to light High-intensity narrow-spectrum light inactivation and wavelength sensitivity of Staphylococcus aureus Inactivation of bacterial pathogens following exposure to light from a 405 nanometer light-emitting diode array Photodynamic therapy for methicillin-resistant Staphylococcus aureus infection in a mouse skin abrasion model Blue light kills Aggregatibacter actinomycetemcomitans due to its endogenous photosensitizers Eradication of Propionibacterium acnes by its endogenic porphyrins after illumination with high intensity blue light Antimicrobial Blue Light Inactivation of Neisseria gonorrhoeae: Roles of Wavelength, Endogenous Photosensitizer, Oxygen, and Reactive Oxygen Species Antimicrobial blue light: An alternative therapeutic for multidrug-resistant gonococcal infections? Photoinactivation of Neisseria gonorrhoeae: A paradigm-changing approach for combating antibiotic-resistant gonococcal infection Phototoxic effect of visible light on Porphyromonas gingivalis and Fusobacterium nucleatum, An in vitro study Antimicrobial effect of blue light using Porphyromonas gingivalis pigment Phototoxic effect of blue light on the planktonic and biofilm state of anaerobic periodontal pathogens Continuous decontamination of an intensive care isolation room during A new proof of concept in bacterial reduction: Antimicrobial action of violet-blue light (405 nm) in ex vivo stored plasma The potential of visible blue light (405 nm) as a novel decontamination strategy for carbapenemase-producing enterobacteriaceae (CPE) Antibacterial activity of blue light against nosocomial wound pathogens growing Planktonically and as mature biofilms How Finsen's light cured lupus vulgaris Killing mechanism of bacteria within multi-species biofilm by blue light Antimicrobial blue light inactivation of pathogenic microbes: State of the art Detailed below are several studies, which show that we do not need UV to kill bacteria, viruses and other pathogens, and that safer wavelengths adjacent to UV, such as violet or blue light, are antimicrobial against microorganisms.
    keywords: blue; coronavirus; covid-19; disease; infections; influenza; light; pandemic; potential; treatment
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        item: #3400 of 7819
          id: cord-295116-eo887olu
      author: Chimmula, Vinay Kumar Reddy
       title: Time Series Forecasting of COVID-19 transmission in Canada Using LSTM Networks()
        date: 2020-05-08
       words: 4711
      flesch: 46
     summary: The rest of this paper is structured as follows: section II describes methods, datasets and LSTM models used in this paper. The predictions of LSTM model are shown in 4 with solid red line.
    keywords: authors; canada; cases; covid-19; data; lstm; model; networks; time; transmission
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        item: #3401 of 7819
          id: cord-295121-4xemmaqt
      author: Ferreira, Eliane de Oliveira
       title: Should We Be Worried About Clostridioides difficile During the SARS-CoV2 Pandemic?
        date: 2020-09-29
       words: 2304
      flesch: 26
     summary: COVID-19 patients receive an empirical antimicrobial therapy with moxifloxacin, cefoperazone, or azithromycin , drugs that are strongly associated with CDI. Although some of those risk factors for CDI are also related to higher probability rates of mortality in severe SARS-CoV-2 infection, the limited number of CDI cases reported among COVID-19 patients is somewhat surprising.
    keywords: cov-2; covid-19; difficile; patients; sars
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        item: #3402 of 7819
          id: cord-295126-lz2jbmcn
      author: Toresdahl, Brett G.
       title: Coronavirus Disease 2019 (COVID-19): Considerations for the Competitive Athlete
        date: 2020-04-06
       words: 2408
      flesch: 44
     summary: Conversely, lymphopenia and leukopenia have been seen in COVID-19 infections, which may assist in diagnosis. 1 The management of COVID-19 infection depends on the severity of symptoms.
    keywords: athlete; covid-19; disease; home; isolation; symptoms; testing
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        item: #3403 of 7819
          id: cord-295138-xud3y0ko
      author: Datta, Niloy R.
       title: Strategies to maximize available resources with minimum cost escalation for improving radiotherapy accessibility in the post COVID-19 era : An analysis for Asia
        date: 2020-09-24
       words: 2790
      flesch: 41
     summary: 19 Strategies for maximal utilization of radiotherapy infrastructure with minimal cost escalation It is assumed that RT centers presently functioning have adequate RT personnel to run their existing facilities for an eight-hour normal working hours of a department. The impact of these strategies on the %RT access and additional TRT unit requirements to achieve 100% RT access were estimated.
    keywords: cancer; centers; countries; covid-19; patients; radiotherapy
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        item: #3404 of 7819
          id: cord-295140-4gdlbc45
      author: Yu, Pey‐Jen
       title: Hypermetabolism and COVID‐19
        date: 2020-06-19
       words: 964
      flesch: 44
     summary: While patients with ARDS have energy expenditures that is approximately 30% above REE 2 , we found most patients with COVID-19 have energy expenditures of greater than 200% of REE. This may explain the high failure rates for mechanical ventilation for these patients and highlights the potential need for increased nutritional requirements for such patients.
    keywords: covid-19; patients; ree
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        item: #3405 of 7819
          id: cord-295142-5sqkdpi8
      author: Han, Y.
       title: The active lung microbiota landscape of COVID-19 patients
        date: 2020-08-23
       words: 3028
      flesch: 39
     summary: mSystems Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19 Genomic diversity of SARS-CoV-2 in Coronavirus Disease 2019 patients IDseq -An Open Source Cloud-based Pipeline and Analysis Service for Metagenomic Pathogen Detection and Monitoring Cytoscape: a software environment for integrated models of biomolecular interaction networks Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19 Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients Lautropia mirabilis gen. nov., sp. nov., a gram-negative motile coccus with unusual morphology isolated from the human mouth Nosocomial urosepsis caused by Enterobacter kobei with aberrant phenotype Klebsiella oxytoca as a causative organism of antibiotic-associated hemorrhagic colitis Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization Occurrence of virulence-associated properties in Enterobacter cloacae Ralstonia pickettii: a persistent gram-negative nosocomial infectious organism Complete Genome Sequence of Faecalibacterium prausnitzii Isolated from the Gut of a Healthy Indian Adult Emerging Infectious Diseases Genomic variation landscape of the human gut microbiome Epidemiology and pathogenesis of Bacillus cereus infections Epidemiology and clinical impact of parainfluenza virus infections in otherwise healthy infants and young children < 5 years old Epidemiology and clinical presentation of the four human parainfluenza virus types Lactobacillus casei downregulates commensals' inflammatory signals in Crohn's disease mucosa Probiotic Lactobacillus rhamnosus downregulates FCER1 and HRH4 expression in human mast cells Induction of cyclooxygenase-2 signaling by Stomatococcus mucilaginosus highlights the pathogenic potential of an oral commensal Translocation of a gut pathobiont drives autoimmunity in mice and humans Supplementary table 1. Here, we analyzed the metatranscriptomic data of bronchoalveolar lavage fluid (BALF) of 19 COVID-19 patients and 23 healthy controls from 6 independent projects and detailed the active microbiota landscape in both healthy individuals and COVID-19 patients.
    keywords: cov-2; covid-19; microbiota; patients; preprint; sars; value
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        item: #3406 of 7819
          id: cord-295144-tyyc81uc
      author: Stradner, Martin H.
       title: Rheumatic Musculoskeletal Diseases and COVID-19 A Review of the First 6 Months of the Pandemic
        date: 2020-10-09
       words: 9915
      flesch: 28
     summary: A single center experience Efficacy and safety of tocilizumab in severe COVID-19 patients: a single-centre retrospective cohort study Interleukin-6 receptor blocking with intravenous tocilizumab in COVID-19 severe acute respiratory distress syndrome: a retrospective case-control survival analysis of 128 patients Tocilizumab in patients with severe COVID-19: a retrospective cohort study Interleukin-6 receptor blockade with subcutaneous tocilizumab in severe COVID-19 pneumonia and hyperinflammation: a case-control study Outcomes in patients with severe COVID-19 disease treated with tocilizumab -a case-controlled study Tocilizumab for treatment of mechanically ventilated patients with COVID-19. Pre-publication reports describe a specific monocyte population in COVID-19 patients, not seen in healthy donors or other viral infections.
    keywords: case; clinical; cohort; coronavirus; course; cov-2; covid-19; disease; infection; inflammatory; patients; risk; rmd; sars; study; syndrome; treatment
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        item: #3407 of 7819
          id: cord-295145-ry4e2izd
      author: Das, Pratik
       title: In-Silico approach for identification of effective and stable inhibitors for COVID-19 main protease (M(pro)) from flavonoid based phytochemical constituents of Calendula officinalis
        date: 2020-07-24
       words: 6455
      flesch: 49
     summary: The virtual molecular docking study reveals that seven bioactive compounds from Calendula officinals have a higher binding affinity toward COVID-19 main protease (M Pro ) as compare to co-crystal ligand inhibitor N3. Molecular dynamics simulation (100 ns) studies of the top three docked compounds (rutin, isorhamnetin-3-O-b-D, and calendoflaside according to the docking score) and co-crystal ligand inhibitor N3 suggest that the top three docked compounds have a good amount of stability, flexibility and binding affinity toward COVID-19 main protease (M pro ) as compare to co-crystal ligand inhibitor N3.
    keywords: amino; apo; binding; covid-19; energy; figure; ligand; pro; protease; rutin
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        item: #3408 of 7819
          id: cord-295150-uw8lwgrh
      author: Sockalingam, Sanjeev
       title: The Impact of Coronavirus Disease 2019 on Bariatric Surgery: Redefining Psychosocial Care
        date: 2020-05-22
       words: 1684
      flesch: 21
     summary: Prevalence of psychiatric disorders among Toronto hospital workers one to two years after the SARS outbreak Attachment style and emotional eating in bariatric surgery candidates: the mediating role of difficulties in emotion regulation Binge eating in bariatric surgery candidates: the role of insecure attachment and emotion regulation Binge eating, loss of control over eating, emotional eating, and night eating after bariatric surgery: results from the Toronto Bari-PSYCH cohort study Exploring the effects of telemedicine on bariatric surgery follow-up: a matched case control study Preoperative and post-operative psychosocial interventions for bariatric surgery patients: a systematic review Content and accuracy of nutrition-related posts in bariatric surgery Facebook support groups Application and effectiveness of eHealth strategies for metabolic and bariatric surgery patients: a systematic review Physical distancing, self-isolation practices, and travel restrictions have necessitated a shift from in-person to remotely delivered bariatric care.
    keywords: care; covid-19; obesity; surgery
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        item: #3409 of 7819
          id: cord-295223-5mlbup1i
      author: Lakhdar, Fayçal
       title: Letter: Neurosurgery at war with the COVID-19 pandemic: patient’s management from an African neurosurgical center
        date: 2020-05-30
       words: 1027
      flesch: 39
     summary: Seeing the rapid worsening of the situation, hospitals' health care administrators had to profoundly reorganize the whole hospital and convert many wards, including the neurosurgery to COVID-19 care units. COVID-19 outbreak has also brought along disastrous socio-economic effects and heavily impacted healthcare activities including our neurosurgical field [1] [2]
    keywords: covid-19; neurosurgery; pandemic; patients
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        item: #3410 of 7819
          id: cord-295237-kdwcnav6
      author: Shen, Cong
       title: Evaluation of dynamic lung changes during coronavirus disease 2019 (COVID-19) by quantitative computed tomography
        date: 2020-09-19
       words: 3505
      flesch: 55
     summary: The volume-related parameters (including the lesion volume, lung volume and their ratio) and density-related parameters (including mean lesion density and lesion density lower than -400HU) were calculated quantitatively. The lesions are detected automatically and the parameters including lesion volume (LeV/mL), lesion percentage to lung volume (LeV%), mean lesion density (MLeD/HU), low attenuation area lower than – 400HU (LAA-400%), and lesion weight (LM/mL*HU) are computed for quantification.
    keywords: changes; covid-19; density; lesion; lobe; lung; volume
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        item: #3411 of 7819
          id: cord-295243-6osemfvk
      author: Jackson, Debra
       title: Life in the pandemic: Some reflections on nursing in the context of COVID‐19
        date: 2020-04-12
       words: 2291
      flesch: 52
     summary: Nurses generally become nurses because of the desire to help people regain and maintain optimal health, and here, we have a situation where there may be very few options to help those who are seriously ill because of COVID-19. We know from our colleagues that despite being actively engaged in this fight against COVID-19, in a way that few other professions are, and despite appearing calm and professional; like everyone else, many nurses are also experiencing fear of the unknown and concern for what lies ahead, for themselves, their patients, colleagues and their own families and friends.
    keywords: covid-19; health; nurses; nursing; people
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        item: #3412 of 7819
          id: cord-295270-6ptaxg74
      author: Titanji, Boghuma K
       title: Response to Correspondence: Baricitinib – Impact on COVID-19 Coagulopathy? Jorgensen et. al.
        date: 2020-08-14
       words: 504
      flesch: 49
     summary: All of the cohort studies of baricitinib for COVID-19 treatment led to significant decline in inflammatory M a n u s c r i p t markers for patients who received the drug 2,3,8 . Drug Saf Baricitinib restrains the immune dysregulation in COVID-19 patients.
    keywords: covid-19
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        item: #3413 of 7819
          id: cord-295274-gzkfy70s
      author: Mecham, Jeffrey C.
       title: Utility of Tracheostomy in Patients With COVID‐19 and Other Special Considerations
        date: 2020-05-12
       words: 2903
      flesch: 30
     summary: One concern for healthcare professionals managing the airways of COVID-19 patients is the risk of viral exposure during aerosol-generating procedures, including intubation and tracheostomy. Although there is no readily available data on the number of patients requiring tracheostomy, given the volume and prolonged course of mechanically ventilated patients, it is prudent to compile resources and establish recommendations for performing tracheostomy in COVID-19 patients.
    keywords: bedside; covid-19; exposure; patients; risk; tracheostomy
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        item: #3414 of 7819
          id: cord-295276-fic96llm
      author: Corpuz, Jeff Clyde G
       title: COVID-19: spiritual interventions for the living and the dead
        date: 2020-09-15
       words: 600
      flesch: 54
     summary: 4 The Philippines, a predominantly Christian country in Southeast Asia, has the highest number of COVID-19 cases in the entire region. key: cord-295276-fic96llm authors: Corpuz, Jeff Clyde G title: COVID-19: spiritual interventions for the living and the dead date: 2020-09-15 journal: J Public Health (Oxf) DOI: 10.1093/pubmed/fdaa167 sha: doc_id: 295276 cord_uid: fic96llm In a recently published correspondence to the editor of this journal, the authors have called for a need to address the risk and dangers of preparing of funeral directors in handling the dead.
    keywords: covid-19; dead
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        item: #3415 of 7819
          id: cord-295287-j3gm9vpz
      author: Michard, Frédéric
       title: Haemodynamic Monitoring and Management in COVID-19 Intensive Care Patients: An International Survey
        date: 2020-08-09
       words: 2874
      flesch: 39
     summary: According to respondents, a majority of COVID-19 ICU patients frequently or very frequently received continuous vasopressor support (56%) and had an echocardiography performed (54%). Our survey confirms that vasopressor support is not uncommon in COVID-19 ICU patients and suggests that different cardiac function phenotypes may be observed.
    keywords: covid-19; fluid; patients; respondents; responsiveness
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        item: #3416 of 7819
          id: cord-295324-t1zvz1zg
      author: Liu, Yin
       title: Mental Health Status of Paediatric Medical Workers in China During the COVID-19 Outbreak
        date: 2020-07-21
       words: 3361
      flesch: 45
     summary: Paediatric medical workers have been an important part of this battle and under enormous pressure. During the COVID-19 outbreak, depression, anxiety and stress are present to varying degrees among paediatric medical workers across the country.
    keywords: anxiety; depression; medical; paediatric; stress; workers
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        item: #3417 of 7819
          id: cord-295341-wkehj39d
      author: Faqihi, Fahad
       title: Comment on Hu et al: The cytokine storm and COVID‐19
        date: 2020-08-06
       words: 737
      flesch: 35
     summary: TPE still carries the risk of exposure to a highly transmissible virus; hence, proper application of personal protective equipment by the staff, careful handling of the TPE devices, and utilization of the pertinent disposables as biohazardous materials is deemed to be necessary as should be the case for all extracorporeal blood purification therapies used in COVID-19 patients. The cytokine storm and COVID-19 Is a Cytokine Storm Relevant to COVID-19? Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Dysregulation of immune response in patients with COVID-19 in Wuhan, China Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China Therapeutic Plasma Exchange in Adults with Severe COVID-19 Infection Effectiveness of convalescent plasma therapy in severe COVID-19 patients Treatment of 5 Critically Ill Patients With With Convalescent Plasma Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19: A Randomized Clinical Trial Dengue antibody-dependent enhancement: Knowns and unknowns Positive RT-PCR Test Results in Patients Recovered From COVID-19 SARS-CoV-2 viral load in upper respiratory specimens of infected patients Recurrent Positive Reverse Transcriptase-Polymerase Chain Reaction Results for Coronavirus Disease 2019 in Patients Discharged From a Hospital in China Effect of Targeted Polymyxin B Hemoperfusion on 28-Day Mortality in Patients With Septic Shock and Elevated Endotoxin Level: The EUPHRATES Randomized Clinical Trial Use of therapeutic plasma exchange as a rescue therapy in 2009 pH1N1 influenza A--an associated respiratory failure and hemodynamic shock Extrapulmonary manifestations of COVID-19 Dexamethasone in Hospitalized Patients with Covid-19 -Preliminary Report
    keywords: covid-19; patients; tpe
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        item: #3418 of 7819
          id: cord-295357-dv1fxprr
      author: Xiang, Yu-Tao
       title: The COVID-19 outbreak and psychiatric hospitals in China: managing challenges through mental health service reform
        date: 2020-03-15
       words: 1816
      flesch: 33
     summary: As an alternative, isolation wards have been established in psychiatric hospitals for psychiatric patients with suspected and confirmed COVID-19, but this option could increase the risk of hospital-acquired infection especially if there is inadequate capacity for infection control in these hospitals [1] . key: cord-295357-dv1fxprr authors: Xiang, Yu-Tao; Zhao, Yan-Jie; Liu, Zi-Han; Li, Xiao-Hong; Zhao, Na; Cheung, Teris; Ng, Chee H. title: The COVID-19 outbreak and psychiatric hospitals in China: managing challenges through mental health service reform date: 2020-03-15 journal: Int J Biol Sci DOI: 10.7150/ijbs.45072 sha: doc_id: 295357 cord_uid: dv1fxprr Recently, more than 300 Chinese patients with psychiatric disorders were diagnosed with the 2019 novel coronavirus disease (COVID-19).
    keywords: china; covid-19; health; hospitals; patients
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        item: #3419 of 7819
          id: cord-295391-e5it7nxl
      author: Alahmadi, Adel Salah
       title: Residents' Perceived Impact of COVID-19 on Saudi Ophthalmology Training Programs-A Survey
        date: 2020-11-03
       words: 3270
      flesch: 45
     summary: Eye (Lond) Impact of COVID-19 pandemic on general surgery training program: an Italian experience Impact of the COVID-19 pandemic on ophthalmology residency training in Portugal The impact of COVID-19 related lockdown on ophthalmology training programs in India -outcomes of a survey Impact of COVID-19 on ophthalmic specialist training in the United Kingdom-the trainees' perspective. A questionnaire was sent to all residents (n-183) currently enrolled in SCFHS accredited ophthalmology training programs, between 7 and 14 July 2020.
    keywords: covid-19; health; impact; ophthalmology; pandemic; participants; residents; training
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        item: #3420 of 7819
          id: cord-295393-aln51r9y
      author: Chamorro-Pareja, Natalia
       title: Unexpected high mortality in COVID-19 and diabetic ketoacidosis()()
        date: 2020-06-24
       words: 908
      flesch: 48
     summary: In conclusion, mortality in patients with COVID-19 and DKA at our institution was higher than expected when compared with patients admitted historically with DKA in the United States 4 and the mortality for hospitalized COVID-19 patients in our area. 11, 12 (8) COVID-19 pandemic, coronaviruses, and diabetes mellitus Letter to the Editor: Diabetes patients with COVID-19 need better blood glucose management in Wuhan COVID-19 infection may cause ketosis and ketoacidosis Trends in Diabetic Ketoacidosis Hospitalizations and In-Hospital Mortality -United States Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area Variation in COVID-19 Hospitalizations and Deaths Across New York City Boroughs Clinical course and mortality risk of severe COVID-19 Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan The COVID-19 Pandemic: a Call to Action to Identify and Address Racial and Ethnic Disparities Severe obesity, increasing age and male sex are independently associated with worse in-hospital outcomes, and higher in-hospital mortality Incidences of Severe Hypoglycemia and Diabetic Ketoacidosis and Prevalence of Microvascular Complications Stratified by Age and Glycemic Control in U.S. Adult Patients With Type 1 Diabetes: A Real-World Study Letter to the Editor: COVID-19 in patients with diabetes: Risk factors that increase morbidity Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS
    keywords: covid-19; patients
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        item: #3421 of 7819
          id: cord-295398-soa71kwx
      author: Moghadas, Seyed M.
       title: The implications of silent transmission for the control of COVID-19 outbreaks
        date: 2020-07-28
       words: 1959
      flesch: 25
     summary: We found that the majority of incidences may be attributable to silent transmission from a combination of the presymptomatic stage and asymptomatic infections. We found that the majority of incidences may be attributable to silent transmission from a combination of the presymptomatic stage and asymptomatic infections.
    keywords: asymptomatic; infections; presymptomatic; transmission
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        item: #3422 of 7819
          id: cord-295407-aq011b97
      author: Pettus, Katherine
       title: Availability of Internationally Controlled Essential Medicines in the COVID-19 Pandemic
        date: 2020-05-07
       words: 1470
      flesch: 21
     summary: Global health experts describe lack of access to essential palliative care medicines as a critical public health issues, and opioids, in particular morphine, as essential for the relief of severe health-related suffering. This in spite of the fact that the WHO and other UN treaty bodies recognize palliative care and pain relief as elements of the right to health (6) .
    keywords: care; covid-19; health; medicines
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        item: #3423 of 7819
          id: cord-295412-ow9lqhrw
      author: Chaturvedi, Seemant
       title: The interplay between COVID 19 and non-communicable diseases
        date: 2020-07-01
       words: 618
      flesch: 45
     summary: First, it is somewhat paradoxical that high income countries with better hospital infrastructure are nevertheless having high rates of COVID-19 mortality. As the authors indicate, since high income countries have longer life expectancy, this creates a larger group of elderly individuals who are vulnerable to COVID-19.
    keywords: covid-19; stroke
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        item: #3424 of 7819
          id: cord-295414-v10454ns
      author: Baktash, Vadir
       title: Vitamin D status and outcomes for hospitalised older patients with COVID-19
        date: 2020-08-26
       words: 3787
      flesch: 40
     summary: These patients were investigated with real-time reverse transcriptase-PCR (RT-PCR) assay for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) on nasopharyngeal swab, blood tests including vitamin D levels (25-hydroxyvitamin D (25(OH)D), basic observations, and chest X-ray (CXR) and/or chest CT. All patients had vitamin D levels checked in keeping with good medical practice.
    keywords: covid-19; deficiency; infection; outcomes; patients; serum; study; vitamin
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        item: #3425 of 7819
          id: cord-295431-p9iy7uaf
      author: Atangana, Ernestine
       title: Facemasks simple but powerful weapons to protect against COVID-19 spread: Can they have sides effects?
        date: 2020-09-30
       words: 9780
      flesch: 49
     summary: Also, no correlation was observed between the infected cases and the death rate of individuals with COVID-19 virus. According to Xie and Zhu, [28] when reporting on the daily confirmed cases of COVID-19 virus, they conveyed that a 1% increase of individuals were infected was associated to 4.861%, as the average temperature between lag (0 -14
    keywords: air; blood; carbon; concentration; covid-19; dioxide; facemasks; health; process; respiratory; results; spread; temperature; virus; wind
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        item: #3426 of 7819
          id: cord-295475-o3ns4cfn
      author: Dastan, Farzaneh
       title: Tocilizumab administration in a refractory case of COVID-19
        date: 2020-06-02
       words: 883
      flesch: 41
     summary: In conclusion, tocilizumab may be considered a salvage therapeutic agent in COVID-19 patients who did not respond to other agents. Euro surveillance : bulletin Europeen sur les maladies transmissibles The cytokine release syndrome (CRS) of severe COVID-19 and Interleukin-6 receptor (IL-6R) antagonist Tocilizumab may be the key to reduce the mortality COVID-19 patients with at least a six-day follow up: A pilot observational study Clinical Course of COVID-19 in a Liver Transplant Recipient on Hemodialysis and Response to Tocilizumab Therapy: A Case Report Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in patients with severe COVID-19 Effective treatment of severe COVID-19 patients with tocilizumab The risk of tuberculosis disease in rheumatoid arthritis patients on biologics and targeted therapy:
    keywords: covid-19; oxygen; tocilizumab
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        item: #3427 of 7819
          id: cord-295479-mcfqs7vf
      author: Davido, Benjamin
       title: Post-COVID-19 chronic symptoms: a post-infectious entity?()
        date: 2020-07-23
       words: 196
      flesch: 9
     summary: The ALBACOVID registry Cerebrovascular disease in patients with COVID-19: 106 neuroimaging, histological and clinical description Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 Chikungunya-Induced Arthritis in Reunion Island: A 113 Long-Term Observational Follow-Up Study Showing Frequently Persistent Joint 114 Some Cases of Persistent Chikungunya Immunoglobulin M Positivity, and 115 Surprisingly today, while we are fearing a second wave, we receive more and more of those COVID-19 : point épidémiologique du 21 mai Assistance Publique-Hôpitaux de Paris' response to the COVID-19 88 pandemic Anosmia and Ageusia: Common Findings 90 in COVID-19 Patients Patients Recovered from COVID-19 Active Epstein-Barr virus infection in 95 post-viral fatigue syndrome serological IgG antibody response on the Abbott Architect for established SARS-CoV-99 2 infection Neurologic manifestations in hospitalized patients 102 with COVID-19:
    keywords: covid-19
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        item: #3428 of 7819
          id: cord-295513-q5f8d0ig
      author: Zhao, Pengcheng
       title: A Comparison of Infection Venues of COVID-19 Case Clusters in Northeast China
        date: 2020-06-03
       words: 6212
      flesch: 55
     summary: In all three provinces, most cases had recorded contacts with other cases and were therefore grouped into case clusters. We mainly analysed the effect of intervention in various regions and focused on the frequency of case clusters in various locations.
    keywords: cases; city; contacts; covid-19; figure; infection; number; provinces
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        item: #3429 of 7819
          id: cord-295516-hgqwef94
      author: Veerasuri, S.
       title: Impact of COVID-19 on UK radiology training: a questionnaire study
        date: 2020-08-12
       words: 4417
      flesch: 47
     summary: Twenty-nine of 47 (62%) radiology trainees within the school completed the questionnaire. key: cord-295516-hgqwef94 authors: Veerasuri, S.; Vekeria, M.; Davies, S. E.; Graham, R.; Rodrigues, J. title: Impact of COVID-19 on UK radiology training: a questionnaire study date: 2020-08-12 journal: Clin Radiol DOI: 10.1016/j.crad.2020.07.022 sha: doc_id: 295516 cord_uid: hgqwef94 Abstract Aim To understand the impact of COVID-19 on radiology trainee experience and well-being.
    keywords: covid-19; pandemic; r n; radiology; trainees
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        item: #3430 of 7819
          id: cord-295523-5pv7kw6i
      author: Picchianti Diamanti, Andrea
       title: Cytokine Release Syndrome in COVID-19 Patients, A New Scenario for an Old Concern: The Fragile Balance between Infections and Autoimmunity
        date: 2020-05-08
       words: 7916
      flesch: 31
     summary: SARS patients with a more severe disease displayed higher serum levels of pro-inflammatory cytokines (IFN-γ, IL-1, IL-6) and chemokines (including IL-8) Indeed, in CRS patients, infections principally involve the respiratory tract.
    keywords: activation; anti; arthritis; cells; cov-2; covid-19; crs; cytokine; disease; il-6; infection; patients; response; sars; syndrome; tnf; treatment
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        item: #3431 of 7819
          id: cord-295527-d5laummv
      author: El-Baba, Firas
       title: Prolonged RNA shedding of the 2019 novel coronavirus in an asymptomatic patient with a VP shunt
        date: 2020-09-14
       words: 1829
      flesch: 47
     summary: This pathophysiology may explain why our patient with a VP shunt had prolonged viral shedding thus illustrating a VP shunt as a possible predisposition for prolonged viral shedding and a potential viral niche for COVID-19. 15 To our knowledge, our case of viral shedding for 36 days is the longest reported in a relatively young, asymptomatic patient or in a patient with a VP shunt demonstrating a VP shunt as a possible predisposition for prolonged viral shedding and possible asymptomatic infectivity.
    keywords: coronavirus; covid-19; patient; shedding
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        item: #3432 of 7819
          id: cord-295536-dbpt4dhr
      author: Shook, Natalie J.
       title: Disease avoidance in the time of COVID-19: The behavioral immune system is associated with concern and preventative health behaviors
        date: 2020-08-20
       words: 4605
      flesch: 36
     summary: Identifying psychological factors that may encourage engagement in preventative health behaviors is crucial. Germ aversion and pathogen disgust sensitivity were the two variables most consistently associated with COVID-19 concern and preventative health behaviors, while accounting for demographic, health, and psychosocial covariates.
    keywords: behaviors; concern; covid-19; disease; disgust; health; participants
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        item: #3433 of 7819
          id: cord-295569-5dakd9en
      author: Ogaugwu, Christian
       title: Effect of Weather on COVID-19 Transmission and Mortality in Lagos, Nigeria
        date: 2020-08-18
       words: 2488
      flesch: 42
     summary: This study therefore explored the effects of daily temperature and humidity on COVID-19 transmission and mortality in Lagos state, the epicenter of COVID-19 in Nigeria. Our results showed that atmospheric temperature has a significant weak negative correlation with COVID-19 transmission in Lagos.
    keywords: correlation; covid-19; lagos; temperature; transmission
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        item: #3434 of 7819
          id: cord-295593-e4akxqv5
      author: Bull-Otterson, Lara
       title: Hydroxychloroquine and Chloroquine Prescribing Patterns by Provider Specialty Following Initial Reports of Potential Benefit for COVID-19 Treatment — United States, January–June 2020
        date: 2020-09-04
       words: 2875
      flesch: 31
     summary: New prescriptions by specialists who did not typically prescribe these medications (defined as specialties accounting for ≤2% of new prescriptions before 2020) increased from 1,143 prescriptions in February 2020 to 75,569 in March 2020, an 80-fold increase from March 2019. New prescriptions for hydroxychloroquine or chloroquine in March 2020 (222,382) were 7.2-fold higher than the 30,737 prescriptions in March 2019; in April, the number of new prescriptions (106,184) was 3.3-fold higher than the 31,748 in April 2019 (Table) .
    keywords: april; covid-19; hydroxychloroquine; march; new; prescriptions
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        item: #3435 of 7819
          id: cord-295603-mk9oartb
      author: Yu, Xiaoqi
       title: Retrospective detection of SARS-CoV-2 in hospitalized patients with influenza-like illness
        date: 2020-07-05
       words: 1993
      flesch: 43
     summary: Influenza (Flu) and other respiratory viruses, including respiratory syncytial virus (RSV), parainfluenza virus (PIV), rhinovirus (HRV), human metapneumovirus (HMPV), enterovirus (EV), adenovirus (AdV), bocavirus (HBoV), coronavirus (OC43, 229E, and HKU1), severe acute respiratory syndrome coronavirus (SARS-CoV) were detected by real-time PCR assay (Roche, Germany). Additionally, among 6662 patients with influenza-like illness from 1 December 2017 to 31 March 2020, the overall number of patients positive for influenza and other respiratory viruses during the COVID-19 period decreased significantly when compared with that in the same period of the last two years, reflecting that public health interventions can effectively control the spread of common respiratory viruses.
    keywords: cov-2; covid-19; influenza; patients; sars
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        item: #3436 of 7819
          id: cord-295622-znmpheia
      author: Simione, Luca
       title: Differences Between Health Workers and General Population in Risk Perception, Behaviors, and Psychological Distress Related to COVID-19 Spread in Italy
        date: 2020-09-04
       words: 9875
      flesch: 45
     summary: We found that health workers reported higher risk perception, level of worry, and knowledge as related to COVID-19 infection compared to the general population. However, on the one hand, doctors and other health workers multiplied their alarms relatively to this critical situation and to the related recommendations regarding behaviors to be followed and the hygienic conduct to be implemented; on the other hand, there were daily episodes of violation of such medical recommendations by the population, apparently only scarcely aware of the problem.
    keywords: anxiety; area; covid-19; group; health; infection; italy; med; participants; people; perception; risk; stress; workers
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        item: #3437 of 7819
          id: cord-295681-l414z6gc
      author: Chow, Justin
       title: Cardiovascular Collapse in COVID-19 Infection: The Role of Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO)
        date: 2020-04-08
       words: 2583
      flesch: 18
     summary: key: cord-295681-l414z6gc authors: Chow, Justin; Alhussaini, Anhar; Calvillo-Argüelles, Oscar; Billia, Filio; Luk, Adriana title: Cardiovascular Collapse in COVID-19 Infection: The Role of Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO) date: 2020-04-08 journal: CJC Open DOI: 10.1016/j.cjco.2020.04.003 sha: doc_id: 295681 cord_uid: l414z6gc COVID-19 has been associated with cardiovascular complications including acute cardiac injury, heart failure and cardiogenic shock. We identified potential clinical scenarios (cardiac injury, myocardial infarction with and without obstructive coronary artery disease, viral myocarditis, and decompensated heart failure) leading to CS and risk factors for poor/uncertain benefit (age, sepsis, mixed/predominantly vasodilatory shock, prothrombotic state and/or coagulopathy, severe acute respiratory distress syndrome, multi-organ failure or high-risk prognostic scores) specific to using VA-ECMO as BTR in COVID-19 infection.
    keywords: cardiac; coronavirus; covid-19; ecmo; patients
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        item: #3438 of 7819
          id: cord-295693-45etqt72
      author: McClure, Elizabeth S
       title: Racial Capitalism within Public Health: How Occupational Settings Drive COVID-19 Disparities
        date: 2020-07-03
       words: 3452
      flesch: 33
     summary: Selective use of race-specific algorithms for workers’ compensation reduces industries’ liability for worker health, illustrating racial capitalism operating within public health. When applying an algorithm to Black workers that is not race corrected, 94% of the Black workers would qualify for compensation.
    keywords: capitalism; compensation; covid-19; epidemiology; function; health; hearing; lung; race; workers
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        item: #3439 of 7819
          id: cord-295700-lzaxzuwe
      author: Shi, Shaobo
       title: Characteristics and clinical significance of myocardial injury in patients with severe coronavirus disease 2019
        date: 2020-05-11
       words: 3846
      flesch: 38
     summary: Table 3 summarized the distribution of death-related complications in included patients, including ARDS (98.4%), acute respiratory failure (90.3%), acute myocardial injury (30.6%), acute heart failure (19.4%), multiple organ failure syndrome (9.7%), shock (6.5%), and sudden death (1.6%). Similar to SARS in 2003, acute respiratory distress syndrome (ARDS) is usually considered to be an acute process confined to the lungs and results in a high mortality rate in COVID-19 patients.
    keywords: age; covid-19; death; disease; hospital; injury; patients; risk
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        item: #3440 of 7819
          id: cord-295703-no45mgyd
      author: ALTAY, O.
       title: Combined metabolic cofactor supplementation accelerates recovery in mild-to-moderate COVID-19
        date: 2020-10-05
       words: 3980
      flesch: 43
     summary: A randomized controlled trial Effects of N-acetylcysteine treatment in acute respiratory distress syndrome: A meta-analysis L-Carnitine preserves endothelial function in a lamb model of increased pulmonary blood flow Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α 2b Plus Ribavirin: Effect on Work Performance; A Randomized Clinical Trial Combination of niacin and fenofibrate with lifestyle changes improves dyslipidemia and hypoadiponectinemia in HIV patients on antiretroviral therapy: results of heart positive Serine Metabolism Supports Macrophage IL-1β Production Long-Term l-Serine Administration Reduces Food Intake and Improves Oxidative Stress and Sirt1/NFκB Signaling in the Hypothalamus of Aging Mice Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults Nicotinamide riboside is uniquely and orally bioavailable in mice and humans Extrapulmonary manifestations of COVID-19 Abnormal Liver Tests in COVID-19: A Retrospective Observational Cohort Study of 1827 Patients in a Major U.S. Hospital Network Gastrointestinal, hepatobiliary, and pancreatic manifestations of COVID-19 Prevalence and Characteristics of Gastrointestinal Symptoms in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in the United States: A Multicenter Cohort Study Abnormal liver function tests in COVID-19 patients: relevance and potential pathogenesis L-Serine Supplementation Attenuates Alcoholic Fatty Liver by Enhancing Homocysteine Metabolism in Mice and Rats Serine Is an Essential Metabolite for Effector T Cell Expansion Combined Treatment with L-Carnitine and Nicotinamide Riboside Improves Hepatic Metabolism and Attenuates Obesity and Liver Steatosis Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity Discoveries of Nicotinamide Riboside as a Nutrient and Conserved <em>NRK</em> Moreover, a large number of clinical trials have been performed for repositioning existing drugs for effective treatment of COVID-19 patients (7, 8) .
    keywords: cmcs; covid-19; day; license; medrxiv; patients; placebo; preprint; study; treatment
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        item: #3441 of 7819
          id: cord-295709-9whgh5b3
      author: Macias, J.
       title: Similar incidence of Coronavirus Disease 2019 (COVID-19) in patients with rheumatic diseases with and without hydroxychloroquine therapy
        date: 2020-05-20
       words: 1788
      flesch: 56
     summary: Because of this, in this study we aimed to compare the incidence of COVID-19 in Spanish patients with autoimmune rheumatic diseases treated with HCQ and without HCQ therapy, during seven weeks in the pandemic. Data on this issue may provide us with worthy information on the potential of HCQ therapy as a prophylactic strategy, which may help to better design clinical trials.
    keywords: covid-19; hydroxychloroquine; medrxiv; preprint
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        item: #3442 of 7819
          id: cord-295715-d8zrn42r
      author: Kim, Jungkeun
       title: Effect of COVID-19 on Preference for Private Dining Facilities in Restaurants
        date: 2020-07-21
       words: 1934
      flesch: 49
     summary: Understanding customers' privacy-seeking tendencies and seating behaviors to create effective restaurant environments The ownership distance effect: The impact of traces left by previous owners on the evaluation of used goods Impact of the Perceived Threat of COVID-19 on Variety-seeking Nudging to reduce the perceived threat of coronavirus and stockpiling intention Historical prevalence of infectious diseases within 230 geopolitical regions: A tool for investigating origins of culture Severity versus frequency of acts of terrorism: Which has a larger impact on tourism demand Tourism, crime, and international security issues Exploring tourists' experience at private social dining: Dimensionality and satisfaction Perceived travel risks regarding terrorism and disease: The case of Thailand Independent restaurants brace for the unknown. Integrating the theories about the psychology of risk with research on preference for private dining, we predict that the prominence of the virus systematically increases preference for private dining.
    keywords: dining; study; table; threat
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        item: #3443 of 7819
          id: cord-295720-eeqv5xa4
      author: Umeizudike, Kehinde Adesola
       title: Nigerian undergraduate dental students’ knowledge, perception, and attitude to COVID‐19 and infection control practices
        date: 2020-09-21
       words: 4205
      flesch: 48
     summary: Clinical dental students are expected to possess an in-depth knowledge particularly due to their access to the social media and television which were their most frequent source of information in the present study. Prior to the pandemic, white clinical coats were worn over personal clothes by clinical dental students in Nigeria during school hours in the dental clinics.
    keywords: control; covid-19; dental; infection; knowledge; nigeria; students; study; undergraduate
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        item: #3444 of 7819
          id: cord-295767-92oxdmxq
      author: Aga, Syed Sameer
       title: Évaluation de la santé mentale et des diverses stratégies d'adaptation dans la population générale vivant sous l'emprise de la COVID à travers le monde : Une étude transversal
        date: 2020-07-28
       words: 3804
      flesch: 46
     summary: Our study aimed to investigate the immediate impact of the COVID-19 pandemic enforced lockdown on mental health and quality of life among general population aged 18 years and to identify various coping strategies used under lockdown. o To identify various coping strategies used under lockdown.
    keywords: anxiety; covid-19; depression; les; lockdown; participants; stress
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        item: #3445 of 7819
          id: cord-295794-glcg36si
      author: Seghers, Victor J.
       title: After the initial COVID-19 surge: a phased radiology departmental re-opening plan
        date: 2020-08-22
       words: 4753
      flesch: 33
     summary: As radiology departments begin recovery operations, some will attempt to restore familiar routines, processes and workflows. Greater awareness of the negative impact of implicit bias within radiology departments as well as recruitment and mentorship programs to prioritize diversity and inclusion can ensure that faculty and staff better reflect the communities in which they serve.
    keywords: cov-2; covid-19; department; hospital; imaging; operations; patients; plan; radiology; reopening; staff; teams; testing
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        item: #3446 of 7819
          id: cord-295798-x7or932x
      author: Ferrey, Antoney J.
       title: A Case of Novel Coronavirus Disease 19 in a Chronic Hemodialysis Patient Presenting with Gastroenteritis and Developing Severe Pulmonary Disease
        date: 2020-03-28
       words: 3037
      flesch: 42
     summary: [17] ; however, whereas an emerging agent for COVID-19 infection is remdesivir [18] , unfortunately patients with ESRD are excluded from current trials. First Case of 2019 Novel Coronavirus in the United States Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study Q&A:
    keywords: case; coronavirus; covid-19; day; dialysis; disease; infection; patients; symptoms
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        item: #3447 of 7819
          id: cord-295829-e1tk8qvw
      author: Dua, Anahita
       title: DVT Protocol Optimization to Minimize Healthcare Worker Exposure in COVID-19
        date: 2020-08-11
       words: 2245
      flesch: 38
     summary: 10 Across the country an increase in COVID-19 patients is resulting in a rise of DVT US testing 12 requests which in turn results in significant exposure for vascular technologists. We recommend implementing 18 both protocols as a joint effort to decrease technologist exposure time and volume of DVT US at 19 institutions caring for patients with COVID-19.
    keywords: covid-19; dimer; dvt; patients; protocol
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        item: #3448 of 7819
          id: cord-295853-lxakf79k
      author: Kumar, Pavan
       title: Forecasting the dynamics of COVID-19 Pandemic in Top 15 countries in April 2020: ARIMA Model with Machine Learning Approach
        date: 2020-03-31
       words: 1721
      flesch: 46
     summary: We used the data of cumulative confirmed death and recovery of COVID-19 cases reported from January 21 until March 26, 2020, that were obtained from John Hopkins Coronavirus resource center (https://coronavirus.jhu.edu/). Top countries' data of China, Italy, Spain, and Iran showed highly disastrous mortality and badly effected with a vast number of COVID-19 cases.
    keywords: covid-19; license; medrxiv; preprint
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        item: #3449 of 7819
          id: cord-295891-c9rfy1w7
      author: Zhao, J.
       title: ConceptWAS: a high-throughput method for early identification of COVID-19 presenting symptoms
        date: 2020-11-10
       words: 4067
      flesch: 48
     summary: Subsequently, as new symptoms were reported, health departments and ministries updated the list of COVID-19 symptoms; for example, the U.S. CDC and the Department of Health and Social Care in the UK added loss of smell or taste, a highly indicative symptom [3] to the list in late April and mid-May, respectively [4, 5] . Recent efforts to track COVID-19 symptoms have used methods such as scanning publications or twitter
    keywords: conceptwas; covid-19; license; medrxiv; patients; preprint; review; symptoms
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        item: #3450 of 7819
          id: cord-295957-s17z2ccf
      author: Bordi, Licia
       title: Rapid and sensitive detection of SARS-CoV-2 RNA using the Simplexa™ COVID-19 direct assay
        date: 2020-05-04
       words: 1928
      flesch: 38
     summary: This study was performed at two regional reference laboratories, with the following aims: I) to assess the analytical performances of the newly designed Simplexa™ COVID-19 Direct assay; II) to evaluate its clinical performance as compared to WHO protocols (7, 8) using different types of clinical specimens from patients with laboratory-confirmed COVID-19. All the SARS-CoV-2 samples resulted positive with the reference test (Cormans method), also resulted positive with Simplexa™ COVID-19 Direct assay, with a diagnostic sensitivity of 100% and almost perfect concordance.
    keywords: assay; cov-2; covid-19; sars; simplexa
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        item: #3451 of 7819
          id: cord-295973-41jqgsv0
      author: Singh, Awadhesh Kumar
       title: Chloroquine and hydroxychloroquine in the treatment of COVID-19 with or without diabetes: A systematic search and a narrative review with a special reference to India and other developing countries
        date: 2020-03-26
       words: 3466
      flesch: 42
     summary: Recommendations on screening for chloroquine and hydroxychloroquine retinopathy Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Breakthrough: chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open label non-randomized clinical trial Of chloroquine and COVID-19 Multicenter collaboration group of Department of Science and Technology of Guangdong Province and Health Commission of Guangdong Province for chloroquine in the treatment of novel coronavirus pneumonia Mount Sinai health system treatment guidelines for SARS-CoV-2 infection (COVID-19 Interim clinical guidelines for patients suspected of/confirmed with COVID-19 infection Chloroquine for influenza prevention: a randomised, double-blind, placebo controlled trial A randomized controlled trial of chloroquine for the treatment of dengue in Vietnamese adults Lack of protection against ebola virus from chloroquine in mice and hamsters Chloroquine is effective against influenza A virus in vitro but not in vivo Chloroquine administration does not prevent Nipah virus infection and disease in ferrets Acceleration of viral replication and up-regulation of cytokine levels by antimalarials: implications in malaria-endemic areas Paradoxical effect of chloroquine treatment in enhancing chikungunya virus infection The enigma of the clandestine association between chloroquine and HIV-1 infection Hydroxychloroquine augments early virological response to pegylated interferon plus ribavirin in genotype-4 chronic hepatitis C patients Chloroquine US prescribing information Chloroquine US prescribing information Chloroquine and hydroxychloroquine are associated with reduced cardiovascular risk: a systematic review and meta-analysis A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 In this study, chloroquine was given in dose of 500 mg of chloroquine twice daily in mild to severe COVID-19 pneumonia (see Table 1 ).
    keywords: chloroquine; covid-19; diabetes; drugs; hcq; hydroxychloroquine; patients; sars; treatment
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        item: #3452 of 7819
          id: cord-295995-uabnyomr
      author: Abdelmaksoud, Ayman
       title: Sexually Transmitted COVID19
        date: 2020-07-08
       words: 312
      flesch: 54
     summary: key: cord-295995-uabnyomr authors: Abdelmaksoud, Ayman; Vestita, Michelangelo; Goldust, Mohamad title: Sexually Transmitted COVID19 date: 2020-07-08 journal: Dermatol Ther DOI: 10.1111/dth.13982 sha: doc_id: 295995 cord_uid: uabnyomr nan In their study on healthy women, Yuksel and Ozgor found a significant higher sexual desire and frequencies of sexual intercourse during COVID19 pandemic compared with 6-12 months prior. They concluded that likelihood of transmitting SARS-Cov-2 to sexual partners through vaginal fluids may be low.
    keywords: covid-19
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        item: #3453 of 7819
          id: cord-296031-r6iqiy1n
      author: Tattan-Birch, H.
       title: COVID-19, smoking, vaping and quitting: A representative population survey in England
        date: 2020-06-30
       words: 5199
      flesch: 53
     summary: Bayes factors indicated there was sufficient evidence to rule out large differences in suspected SARS-CoV-2 infection by NRT use and medium differences by e-cigarette use. Conclusions: In a representative sample of the adult population in England, current smokers and long-term ex-smokers had higher odds of suspected SARS-CoV-2 infection than never smokers, but there were no large differences by NRT or e-cigarette use.
    keywords: cigarette; covid-19; infection; preprint; sars; smokers; smoking; use
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        item: #3454 of 7819
          id: cord-296072-w8nwj3u6
      author: Al-karawi, D.
       title: Machine Learning Analysis of Chest CT Scan Images as a Complementary Digital Test of Coronavirus (COVID-19) Patients
        date: 2020-04-17
       words: 2264
      flesch: 46
     summary: Higher frequency ranges are associated with image texture features. Human observers, including trained radiologists, might find it difficult to detect informative features from FFT spectrum images.
    keywords: covid-19; images; license; medrxiv; preprint
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        item: #3455 of 7819
          id: cord-296113-syi2fwuo
      author: Peng, Mian
       title: Two mechanically ventilated cases of COVID-19 successfully managed with a sequential ventilation weaning protocol: Two case reports
        date: 2020-08-06
       words: 2624
      flesch: 45
     summary: A MV protocol attentive to intubation/extubation timing, prone positioning early in MV, infection control, and sequential withdrawal of respiratory support, may be an effective regimen for patients with critical COVID-19. The viral pathogen severe acute respiratory syndrome-related novel coronavirus (SARS-CoV-2, also known as 2019 novel coronavirus or 2019-nCoV), which has been determined to have originated in Wuhan, China, has infected patients around the globe and produced the ongoing grave pandemic
    keywords: coronavirus; covid-19; patients; sars; weaning
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        item: #3456 of 7819
          id: cord-296171-v9co078y
      author: Gialluisi, Alessandro
       title: New challenges from Covid-19 pandemic: an unexpected opportunity to enlighten the link between viral infections and brain disorders?
        date: 2020-05-06
       words: 679
      flesch: 29
     summary: Neurol Sci DOI: 10.1007/s10072-020-04444-z sha: doc_id: 296171 cord_uid: v9co078y nan We read with great interest recent reports of sensorial impairments in Covid-19 patients, both in the early [1] and in a later phase of the infection [2] . Of note, IL-6 action is blocked by tocilizumab, a drug currently used to inhibit cytokine storm in Covid-19 patients [8] .
    keywords: covid-19; disorders
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        item: #3457 of 7819
          id: cord-296174-95ap8qfn
      author: Singh, Arjun Gurmeet
       title: Navigating the impact of COVID‐19 on palliative care for head and neck cancer
        date: 2020-04-27
       words: 1709
      flesch: 49
     summary: Even though it has been established that opioids are necessary for cancer pain, a large part of palliative care patients will face barriers to relief of such suffering. In palliative care services, this apprehension gets exemplified, as these patients have limited life expectancy.
    keywords: care; covid-19; head; palliative; patients
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        item: #3458 of 7819
          id: cord-296182-hhswage4
      author: Meng, Lingzhong
       title: Intubation and Ventilation amid the COVID-19 Outbreak: Wuhan’s Experience
        date: 2020-04-08
       words: 6539
      flesch: 37
     summary: Ventilator management for hypoxemic respiratory failure attributable to H1N1 novel swine origin influenza virus High-frequency oscillatory ventilation versus conventional ventilation for acute respiratory distress syndrome Nursing and infection-control issues during high-frequency oscillatory ventilation Work of breathing during lung-protective ventilation in patients with acute lung injury and acute respiratory distress syndrome: A comparison between volume and pressure-regulated breathing modes Ventilator management for acute respiratory distress syndrome associated with avian influenza A (H7N9) virus infection: A case series Prone positioning in severe acute respiratory distress syndrome Lung recruitment maneuvers for ARDS patients: A systematic review and meta-analysis Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation ACURASYS Study Investigators: Neuromuscular blockers in early acute respiratory distress syndrome Early neuromuscular blockade in the acute respiratory distress syndrome Neuromuscular blockade in acute respiratory distress syndrome: A systematic review and meta-analysis of randomized controlled trials ESICM H1N1 Registry Contributors: Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1) v influenza A infection Corticosteroids as adjunctive therapy in the treatment of influenza Corticosteroids as adjunctive therapy in the treatment of influenza: An updated Cochrane systematic review and meta-analysis González-Martín JM; dexamethasone in ARDS network: Dexamethasone treatment for the acute respiratory distress syndrome: A multicentre, randomised controlled trial Extracorporeal membrane oxygenation for 2009 influenza A(H1N1) acute respiratory distress syndrome Extracorporeal life support: The next step in moderate to severe ARDS-A review and meta-analysis of the literature Elbourne D; CESAR trial collaboration: Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): A multicentre randomised controlled trial Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome and posterior probability of mortality benefit in a post hoc Bayesian analysis of a randomized clinical trial A novel coronavirus outbreak of global health concern A review of isolation gowns in healthcare: Fabric and gown properties Prone position for acute respiratory distress syndrome. Approximately 3.2% of patients with COVID-19 required intubation and invasive ventilation at some point in the disease course.
    keywords: airway; china; covid-19; infection; intubation; lung; oxygenation; patients; pressure; syndrome; ventilation; wuhan
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        item: #3459 of 7819
          id: cord-296208-uy1r6lt2
      author: Greenspan, Hayit
       title: Position paper on COVID-19 imaging and AI: from the clinical needs and technological challenges to initial AI solutions at the lab and national level towards a new era for AI in healthcare
        date: 2020-08-19
       words: 8010
      flesch: 43
     summary: The COVID-19 crisis has seen the emergence of multiple observational studies to support research into understanding disease risk, monitoring disease trajectory, and for the development of diagnostic and prognostic tools, based on a variety of data sources including clinical data, samples and imaging data. It is therefore important that, while conducting efforts to provide access to observational COVID-19 data, we already plan for using part of the data for designing challenges around relevant clinical use cases.
    keywords: analysis; chest; covid-19; data; detection; disease; imaging; learning; lung; pandemic; patients; solutions; systems
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        item: #3460 of 7819
          id: cord-296214-xeezt6f7
      author: Sabatino, Jolanda
       title: Women's perspective on the COVID-19 pandemic: Walking into a post-peak phase
        date: 2020-08-13
       words: 2706
      flesch: 40
     summary: Takotsubo syndrome in COVID-19 patients might well be related to stress-induced adrenergic burst secondary to fever and the inflammatory response to infection. As pulmonary fibrosis rates range 30-45% in COVID-19 patients, this might pose a major care burden
    keywords: children; coronavirus; covid-19; disease; pandemic; patients; women
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        item: #3461 of 7819
          id: cord-296219-zzg9hds0
      author: Battaglini, Denise
       title: Neurological Manifestations of Severe SARS-CoV-2 Infection: Potential Mechanisms and Implications of Individualized Mechanical Ventilation Settings
        date: 2020-08-12
       words: 7500
      flesch: 24
     summary: Furthermore, mechanical ventilation, commonly used in the management of COVID-19 patients, can itself induce an inflammatory response, causing distal organ failure. Despite the paucity of evidence, there are three key hypotheses for the neurological manifestations of COVID-19 patients (Figure 1) : (1) viral neurotropism; (2) a hyperinflammatory and hypercoagulable state; and (3) brainlung crosstalk.
    keywords: acute; brain; cells; coronavirus; cov-2; covid-19; disease; infection; levels; lung; oxygen; patients; pressure; sars; study; syndrome
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        item: #3462 of 7819
          id: cord-296232-6zj99nuw
      author: Talukdar, Jayanta
       title: Potential of natural astaxanthin in alleviating the risk of cytokine storm in COVID-19
        date: 2020-10-16
       words: 7641
      flesch: 38
     summary: Translocation of NF-ĸB/p65 and the levels of IL-6 and TNF-α were reported to decrease markedly following ASX treatment Moreover, ASX treatment was also found to reduce serum levels of LDH, blood urea nitrogen, creatinine, IL-1β, IL-6 and TNF-α, and also attenuated multi organ damage in CLP-induced septic rats [44] .
    keywords: activation; anti; astaxanthin; asx; covid-19; effects; expression; immune; inflammation; injury; oxidative; pathway; ppar; response; signaling; treatment
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        item: #3463 of 7819
          id: cord-296265-mat1x862
      author: Du, Na
       title: Clinical characteristics of family-clustered onset of coronavirus disease 2019 in Jilin Province, China
        date: 2020-09-15
       words: 3138
      flesch: 57
     summary: China SARS and other coronaviruses as causes of pneumonia Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia Pattern of early human-tohuman transmission of Wuhan 2019 novel coronavirus (2019-nCoV) Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China:a descriptive study Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2 Clinical features of patients infected with 2019 novel coronavirus in Wuhan T-cell immunity of SARS-CoV: implications for vaccine development against MERS-CoV Acute respiratory distress syndrome: CT abnormalities at long-term follow-up Acute respiratory distress syndrome: imaging of the injured lung With disease progression, the percentage of lymphocytes in older patients increased, CT images worsened, and the ratio of lymphocytes increased when images revealed inflammation absorption.
    keywords: coronavirus; covid-19; disease; january; patients
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        item: #3464 of 7819
          id: cord-296285-qiez6adj
      author: Boudrioua, M. S.
       title: Predicting the COVID-19 epidemic in Algeria using the SIR model
        date: 2020-04-29
       words: 1443
      flesch: 51
     summary: According to his results, the number of infected cases in Algeria will exceed 5000 on April 7 th , 2020 and it will double to 10000 on April 11 th , 2020. The function (t) S represents the number of susceptible cases at time t .The function (t) I represents the number of infected cases at time t, and the function (t) R is the compartment of recovered cases from the disease.
    keywords: covid-19; epidemic; model; preprint
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        item: #3465 of 7819
          id: cord-296306-xcomjvaa
      author: Rivett, Lucy
       title: Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission
        date: 2020-05-11
       words: 6506
      flesch: 42
     summary: Ward Q is a general medical ward designated as a 'red' clinical area for the care of COVID-19 positive patients, with a Scenario 1 PPE protocol (Tables 4-5). In addition, given SARS CoV-2 was only introduced into the human population in late 2019, there is at present a lack of diversity in circulating strains.
    keywords: asymptomatic; cov-2; covid-19; data; hcw; hcws; sars; screening; self; staff; symptoms; testing; ward
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        item: #3466 of 7819
          id: cord-296312-nh4poc71
      author: Kowitt, Sarah D.
       title: Tobacco Quit Intentions and Behaviors among Cigar Smokers in the United States in Response to COVID-19
        date: 2020-07-25
       words: 4864
      flesch: 51
     summary: We also examined how other correlates were associated with COVID-19 quit intentions and behaviors, including demographics, such as age and race, and tobacco use variables, such as other tobacco use and nicotine dependence. Tobacco use variables included other tobacco use [35] and nicotine dependence (using items that assess nicotine dependence for users of multiple tobacco products)
    keywords: covid-19; intentions; participants; quit; risk; smoking; tobacco; use
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        item: #3467 of 7819
          id: cord-296314-hprl52va
      author: Martins-Filho, Paulo Ricardo
       title: COVID-19 fatality rates related to social inequality in Northeast Brazil: a neighbourhood-level analysis.
        date: 2020-08-06
       words: 1201
      flesch: 46
     summary: In this ecological study, we investigated the association between social inequality and COVID-19 fatality rate in Aracaju municipality, Sergipe state, Northeast Brazil. Additionally, it is estimated that one in five Brazilian adults has two or more morbidities, 3 which may increase the susceptibility to COVID-19 mortality, especially among poor people.
    keywords: conditions; covid-19; mortality; neighbourhoods
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        item: #3468 of 7819
          id: cord-296316-huyw5eo1
      author: Suresh, Padmanaban S.
       title: Curcumin and Coagulopathy in the COVID19 Era
        date: 2020-07-15
       words: 630
      flesch: 28
     summary: COVID-19 patients exhibit thrombotic complications apart from sepsis, pneumonia, respiratory failure, etc., One of the characteristic features of COVID-19 disease is the associated coagulopathy with increased circulating D-dimer concentrations. Evaluating D-dimer concentrations assist in predicting the mortality in COVID-19 patients, and patients with Ddimer levels [ 1 lg/L on admission were associated with higher mortality
    keywords: covid-19; curcumin; patients
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        item: #3469 of 7819
          id: cord-296330-4i02f1ji
      author: Qi, Xiaolong
       title: Clinical course and risk factors for mortality of COVID-19 patients with pre-existing cirrhosis: A multicenter cohort study
        date: 2020-04-28
       words: 3361
      flesch: 49
     summary: key: cord-296330-4i02f1ji authors: Qi, Xiaolong; Liu, Yanna; Fallowfield, Jonathan A.; Wang, Jitao; Wang, Jianwen; Li, Xinyu; Shi, Jindong; Pan, Hongqiu; Zou, Shengqiang; Zhang, Hongguang; Chen, Zhenhuai; Li, Fujian; Luo, Yan; Mei, Mei; Liu, Huiling; Wang, Zhengyan; Li, Jinlin; Yang, Hua; Xiang, Huihua; Li, Xiaodan; Liu, Tao; Zheng, Ming-Hua; Liu, Chuan; Huang, Yifei; Xu, Dan; Li, Xiaoguo; Kang, Ning; He, Qing; Gu, Ye; Zhang, Guo; Shao, Chuxiao; Liu, Dengxiang; Zhang, Lin; Li, Xun; Kawada, Norifumi; Jiang, Zicheng; Wang, Fengmei; Xiong, Bin; Takehara, Tetsuo; Rockey, Don C. title: Clinical course and risk factors for mortality of COVID-19 patients with pre-existing cirrhosis: A multicenter cohort study date: 2020-04-28 journal: nan DOI: 10.1101/2020.04.24.20072611 sha: doc_id: 296330 cord_uid: 4i02f1ji Background: Patients with pre-existing cirrhosis are considered at increased risk of severe coronavirus disease 2019 (COVID-19) but the clinical course in these patients has not yet been reported. This study aimed to provide a detailed report of the clinical characteristics and outcomes among COVID-19 patients with pre-existing cirrhosis.
    keywords: cirrhosis; covid-19; liver; medrxiv; patients; preprint
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        item: #3470 of 7819
          id: cord-296331-i4hyzqcv
      author: Adapa, Sreedhar
       title: COVID-19 Pandemic Causing Acute Kidney Injury and Impact on Patients With Chronic Kidney Disease and Renal Transplantation
        date: 2020-06-04
       words: 5101
      flesch: 47
     summary: medRxiv Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Clinical Characteristics of Coronavirus Disease 2019 in China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Critically Ill Patients With COVID-19 in Washington State A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 Clinical features and treatment of COVID-19 patients in northeast Chongqing Clinical Features of Patients Infected with the 2019 Novel Coronavirus (COVID-19 Coronavirus epidemic: preparing for extracorporeal organ support in intensive care Blood Purification Therapy and Engineering Technology Branch of the Chinese Medical Advocacy Council, and the Blood Purification Therapeutic Committee of the Army. medRxiv Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Kidney impairment is associated with in-hospital death of COVID-19 patients.
    keywords: aki; coronavirus; covid-19; creatinine; disease; infection; kidney; mortality; ncov; patients; sars; studies; transplant
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        item: #3471 of 7819
          id: cord-296342-qyqf60s9
      author: Alvarez Retamales, V.
       title: Racial/Ethnic Disparities in COVID-19 Hospital Admissions
        date: 2020-07-17
       words: 2621
      flesch: 44
     summary: The proportion of non-Hispanic Black patients admitted (36%) is significantly higher than the percentage of the general population (13%), suggesting a significant race-based health disparity or vulnerability to disease (Figure 1 ). . Patients identified as non-Hispanic Black, Hispanic/Latino, and American Indian have a disproportionate burden of hospital admissions, suggesting an increased risk of more severe disease.
    keywords: covid-19; health; license; medrxiv; preprint
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        item: #3472 of 7819
          id: cord-296353-snzdjan9
      author: Fox, Nathan S.
       title: COVID-19 in Pregnant Women: Case Series from One Large New York City Obstetrical Practice
        date: 2020-05-21
       words: 1109
      flesch: 59
     summary: snzdjan9 Objective This study aimed to report a case series of pregnant women in New York City with confirmed or presumed coronavirus disease (COVID-19) infection. These preliminary results are encouraging for pregnant women during the COVID-19 pandemic.
    keywords: covid-19; women
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        item: #3473 of 7819
          id: cord-296363-qgoxlqoq
      author: Khan, Yusra Habib
       title: Threat of COVID-19 Vaccine Hesitancy in Pakistan: The Need for Measures to Neutralize Misleading Narratives
        date: 2020-06-22
       words: 1534
      flesch: 41
     summary: Recently, two well-known political figures raised conspiracy theories against COVID-19 vaccines in Pakistan, stating that COVID-19 is a grand illusion and a conspiracy against Muslim countries. Unfortunately, a conspiracy theory against COVID-19 vaccine is currently being spread in Pakistan.
    keywords: conspiracy; covid-19; pakistan; vaccine
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        item: #3474 of 7819
          id: cord-296375-gf0mgz5x
      author: Zhang, Xi
       title: Comparison of spatiotemporal characteristics of the COVID-19 and SARS outbreaks in mainland China
        date: 2020-10-30
       words: 3282
      flesch: 48
     summary: We found that COVID-19 cases were clustered mainly in Hubei, and other secondary clusters disappeared, except in Shandong. Therefore, in this study, by collecting the daily numbers of newly confirmed COVID-19 and SARS cases during the two epidemics, we aimed to determine the spatial behavior and temporal features of the COVID-19 spread in mainland China and compared them with respective features from the SARS epidemic using spatiotemporal analysis.
    keywords: cases; china; clusters; covid-19; hubei; low; sars
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        item: #3475 of 7819
          id: cord-296384-cejw22ms
      author: Chitturi, Kalyan R.
       title: Transcatheter mitral valve repair with MitraClip for severe mitral regurgitation and cardiogenic shock during the COVID-19 pandemic
        date: 2020-05-23
       words: 756
      flesch: 34
     summary: key: cord-296384-cejw22ms authors: Chitturi, Kalyan R.; Faza, Nadeen N.; Little, Stephen H.; Kleiman, Neal S.; Reardon, Michael J.; Goel, Sachin S. title: Transcatheter mitral valve repair with MitraClip for severe mitral regurgitation and cardiogenic shock during the COVID-19 pandemic date: 2020-05-23 journal: Patients with severe mitral regurgitation (MR) and cardiogenic shock are high-risk surgical candidates and at risk of a poor outcome without intervention.
    keywords: covid-19; pandemic; patients
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        item: #3476 of 7819
          id: cord-296420-n3vyhqpd
      author: England, Andrew
       title: Modifications to mobile chest radiography technique during the COVID-19 pandemic – implications of X-raying through side room windows
        date: 2020-08-03
       words: 3847
      flesch: 47
     summary: The aim of this study was to evaluate the impact on image quality and exposure factors when undertaking such examinations. Image quality (physical and visual), incidence surface air kerma (ISAK), Exposure Index (EI) and Deviation Index (DI) were recorded.
    keywords: control; covid-19; glass; image; quality; radiography; ray; tube; window
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        item: #3477 of 7819
          id: cord-296425-on8er7v9
      author: O’Brien, Edward R.
       title: Sex differences in COVID-19 mortality: opportunity to develop HSP27 (HSPB1) immunotherapy to treat hyper-inflammation?
        date: 2020-08-06
       words: 2712
      flesch: 20
     summary: As well, we recently noted that natural IgG auto-antibodies to HSP27 (AAbs) are detectable in human blood (Chen et al. 2020b ) and demonstrated how HSP27 immune complexes (ICs) form, dock at the cell membrane where they engage with Toll-like receptor 4 (TLR4), and compete with LPS to reduce inflammatory signaling (Shi et al. 2020) . In a phase 3 clinical study, anakinra reduced mortality and the need for supplemental oxygen therapy (mechanical ventilation) in critically ill patients with COVID-19, thereby pointing to the need for further controlled studies (Huet et al. 2020) .
    keywords: covid-19; heat; hsp27; inflammasome; protein; shock
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        item: #3478 of 7819
          id: cord-296426-upwsdgso
      author: Virmani, Sarthak
       title: Identifying a Kidney Transplant Recipient COVID Phenotype to Aid Test Utilization in the Setting of Limited Testing Availability - Does One Exist?
        date: 2020-06-20
       words: 4404
      flesch: 44
     summary: Intriguingly, patients with a history of polyoma BK viremia (BKV) had a higher incidence of testing positive for SARS-CoV-2 compared to patients without history of BKV (80% and 28%, respectively; p= 0.002). Intriguingly, patients with a history of polyoma BK viremia (BKV) had a higher incidence of testing positive for SARS-CoV-2 compared to patients without history of BKV (80% and 28%, respectively; p= 0.002).
    keywords: cov-2; covid-19; infection; ktrs; patients; sars; testing
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        item: #3479 of 7819
          id: cord-296440-18vpg419
      author: Beurnier, Antoine
       title: Characteristics and outcomes of asthmatic patients with COVID-19 pneumonia who require hospitalisation
        date: 2020-07-30
       words: 3554
      flesch: 44
     summary: Indeed, sputum analysis showed that ACE2 expression levels are significantly lower in asthma patients taking ICS than in those not taking ICS, especially when high doses are administrated [19] . However, more concern has been recently raised about thrombosis and pulmonary embolism in COVID-19 patients [28] , underscoring that this complication may be more prevalent in this patient population.
    keywords: asthma; asthmatics; cases; covid-19; non; patients; pneumonia; sars
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        item: #3480 of 7819
          id: cord-296483-x95lwwnm
      author: Kranke, Peter
       title: Geburtshilfliche Anästhesie während der SARS-CoV-2-Pandemie: Übersicht der Handlungsempfehlungen
        date: 2020-04-09
       words: 2006
      flesch: 37
     summary: von COVID-19 beeinflusst werden, es sei denn, der Atemzustand der Frau erfordert eine dringende Entbindung. Einschränkend sollte berücksichtigt werden, dass es sich bislang nur um einen einzigen Fallbericht handelt und es im Rahmen der systemischen Inflammation möglicherweise zu einem erhöhten Transfer von Antikörpern kommen könnte.
    keywords: auf; bei; coronavirus; cov-2; covid-19; dass; der; die; eine; für; infection; patients; sars; und; von; werden
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        item: #3481 of 7819
          id: cord-296494-6kn4mr04
      author: Saban-Ruiz, J.
       title: COVID-19: A Personalized Cardiometabolic Approach for Reducing Complications and Costs. The Role of Aging Beyond Topics
        date: 2020-05-12
       words: 6450
      flesch: 39
     summary: Even more interesting, taking into account that at least 50% of COVID-19 patients have hyperglycaemia on admission or in the first days of hospitalization (25) , the transmembrane domain has a potential N-glycation site (26) that in COVID-19 would deserve further research. COVID-19 patients who develop myocardial injury, usually DM and/or elderly patients, have a more acute presentation, with higher incidence of ADSR and more frequent need for assisted ventilation than those without myocardial injury (64) .
    keywords: ace2; acute; aging; cardiometabolic; cardiovascular; coronavirus; covid-19; diabetes; disease; failure; heart; patients; risk; sars
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        item: #3482 of 7819
          id: cord-296522-ljovvgey
      author: Fitzpatrick, Kevin M.
       title: Facing New Fears During the COVID-19 Pandemic: The State of America’s Mental Health
        date: 2020-08-13
       words: 5615
      flesch: 43
     summary: The current study examines the intersection of COVID-19 fear, worries and perceived threat with social group vulnerabilities and mental health consequences, namely anxiety and depressive symptomatology. With early indicators of concern, worry, and fear among U.S. residents, greater attention is needed on the specific implications of COVID-19 fear on mental health outcomes.
    keywords: anxiety; covid-19; fear; health; pandemic; respondents; threat; worry
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        item: #3483 of 7819
          id: cord-296536-s8n7kgkn
      author: Nagendrappa, Sachin
       title: Recognizing the role of animal-assisted therapies in addressing mental health needs during the COVID-19 Pandemic
        date: 2020-08-27
       words: 635
      flesch: 39
     summary: The role of pets in addressing mental health seems to be promising in this regard. . Psychosocial and psychophysiological effects of human-animal interactions: The possible role of oxytocin Ontological security and connectivity provided by pets: a study in the self-management of the everyday lives of people diagnosed with a long-term mental health condition A Systematic Review of Randomized Controlled Trials of Animal-Assisted Therapy on Psychosocial Outcomes COVID-19 and pets: When pandemic meets panic COVID-19 and mental health: A review of the existing literature.
    keywords: health; pets
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        item: #3484 of 7819
          id: cord-296550-wkmnfph3
      author: Hossain, Mohammad Anwar
       title: Knowledge, attitudes, and fear of COVID-19 during the Rapid Rise Period in Bangladesh
        date: 2020-09-24
       words: 4581
      flesch: 51
     summary: However, our study did find subjects with high fear scores and who were also more likely to follow good preventive practices, as recommended by the health advisory. The majority of the population had high fear scores, with significantly higher scores found in women and elderly adults.
    keywords: bangladesh; covid-19; fear; knowledge; scores; study; subjects; symptoms
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        item: #3485 of 7819
          id: cord-296562-3h2oqb9k
      author: Guillén, Lucía
       title: Preemptive interleukin-6 blockade in patients with COVID-19
        date: 2020-10-08
       words: 4881
      flesch: 36
     summary: Baseline levels and the initial response after TCZ administration of some biomarkers were also useful to predict the clinical outcome; a lower NLR on admission, and lower platelet/d-dimer ratio and hs-cardiac troponin I at 48 h following TCZ initiation were associated with favorable TCZ response. Baseline characteristics of included patients are shown in Table 1 .
    keywords: biomarkers; covid-19; disease; il-6; levels; non; patients; responders; response; tcz; therapy; tocilizumab
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        item: #3486 of 7819
          id: cord-296567-six7u615
      author: Hussain, Akhtar
       title: Clinical considerations for patients with diabetes in times of COVID-19 epidemic
        date: 2020-04-10
       words: 1626
      flesch: 39
     summary: We need to develop a hypothesis to explain the causal path underlying the more severe clinical presentation of COVID-19 infection and subsequent death in diabetic patients. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) -China 2020 Vascular complications of diabetes: mechanisms of injury and protective factors Infections, immunity and diabetes Clinical considerations for patients with diabetes in times of COVID-19 epidemic Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
    keywords: coronavirus; covid-19; diabetes; infection; patients
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        item: #3487 of 7819
          id: cord-296579-oa67njov
      author: d’Ettorre, Gabriella
       title: Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection: A case report
        date: 2020-09-04
       words: 2788
      flesch: 41
     summary: World Health Organization Coronavirus disease 2019 (COVID-19) Situation Report Impact of HIV on the severity of influenza One case of coronavirus disease 2019 (COVID-19) in a patient co-infected by HIV with a low CD4+ T-cell count Co-infection of SARS-CoV-2 and HIV in a patient in Wuhan city COVID-19 in patients with HIV: clinical case series COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients African American COVID-19 mortality: a sentinel event HIV-associated chronic immune activation Type I interferon and HIV: Subtle balance between antiviral activity, immunopathogenesis and the microbiome Heightened innate immune responses in the respiratory tract of COVID-19 patients Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing Increased expression of IL-32 correlates with IFN-(, Th1 and Tc1 in virologically suppressed HIV-1-infected patients Increased SAMHD1 transcript expression correlates with interferon-related genes in HIV-1-infected patients Sex-related differences in markers of immune activation in virologically suppressed HIV-infected patients Clinical features and outcomes of HIV patients with coronavirus disease 2019 Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 Vademecum per la cura delle persone con malattia da COVID-19 Edizione 2.0 A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial The COVID-19 pandemic: a call to action to identify and address racial and ethnic disparities Are clinicians contributing to excess African American COVID-19 deaths? [26] It has also showed that low IFN-I-III levels are produced during SARS-CoV-2 infection despite a consistent chemokine signature in cell lines, primary cell cultures, ferrets and COVID-19 patients.
    keywords: activation; cell; cov-2; covid-19; hiv-1; patients; sars
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        item: #3488 of 7819
          id: cord-296582-55rz7epf
      author: Glick, Sara N.
       title: The Impact of COVID-19 on Syringe Services Programs in the United States
        date: 2020-04-24
       words: 1685
      flesch: 48
     summary: Qualitative data were collected through interviews with SSP program staff and public health staff who support SSP activities in their jurisdictions. HIV incidence among injecting drug users in New York City syringe-exchange programmes Availability of HIV and HCV on-site testing and treatment at syringe service programs in the United States Engaging an unstably housed population with low-barrier buprenorphine treatment at a syringe services program:
    keywords: covid-19; programs; services; ssps; staff
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        item: #3489 of 7819
          id: cord-296588-q2716lda
      author: Hanson, Kimberly E
       title: Infectious Diseases Society of America Guidelines on the Diagnosis of COVID-19
        date: 2020-06-16
       words: 10186
      flesch: 40
     summary: In addition, the limited data showing poor outcomes in COVID-19 positive patients undergoing a major surgical procedure requiring intubation informed decisions to reduce this risk for asymptomatic patients We also did not identify test accuracy studies directly assessing the performance of SARS-CoV-2 NAATs in asymptomatic individuals.
    keywords: asymptomatic; c r; cov-2; covid-19; evidence; individuals; p t; patients; s c; sars; studies; test; testing
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        item: #3490 of 7819
          id: cord-296592-njf6u0v2
      author: Keswani, Rajesh N.
       title: How To Maximize Trainee Education During the COVID-19 Pandemic: Perspectives from Around the World
        date: 2020-05-07
       words: 2548
      flesch: 32
     summary: In a recent North American survey conducted during the pandemic, nearly half of advanced endoscopy trainees were not participating in procedures and the overall therapeutic endoscopy volume had greatly decreased 3 . In this article, we present an assessment of the impact of COVID-19 upon GI trainees, highlight strategies to mitigate its impact on education and well-being, and ultimately return trainees to a new normal endoscopic and clinical practice.
    keywords: endoscopy; learning; pandemic; programs; trainees; training
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        item: #3491 of 7819
          id: cord-296598-aelpasay
      author: Coughlin, Lara N.
       title: Considerations for remote delivery of behavioral economic interventions for substance use disorder during COVID-19 and beyond
        date: 2020-10-04
       words: 2332
      flesch: 17
     summary: EFT improves behavioral economic mechanisms (delay discounting, demand) in human laboratory studies (Stein et al. 2016; Snider, LaConte, and Bickel 2016; Bulley and Gullo 2017 Behavioral economic interventions are positioned to leverage remote substance use monitoring and remote care technology to enhance the delivery of SUD care during COVID-19 and beyond. Behavioral economic treatments, such as contingency management, the substance-free activity session, and episodic future thinking, are positioned to leverage remote monitoring of substance use and to use personalized medicine frameworks to deliver remote interventions in the COVID-19 era and beyond.
    keywords: interventions; substance; use
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        item: #3492 of 7819
          id: cord-296607-h2zwlyz7
      author: Watson, Ryan A.
       title: Anti-coagulant and anti-platelet therapy in the COVID-19 patient: a best practices quality initiative across a large health system
        date: 2020-06-09
       words: 7740
      flesch: 32
     summary: COVID-19 patients may present with hemodynamic instability and increased biomarkers of cardiac injury, specifically troponin and B-Type Natriuretic Peptide. COVID-19 patients, commonly present with shortness of breath secondary to viral pneumonia with critically ill patients progressing to acute respiratory distress syndrome (ARDS).
    keywords: american; anticoagulation; bleeding; covid-19; disease; fibrillation; management; mortality; patients; prophylaxis; risk; stroke; therapy; thrombosis; use
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        item: #3493 of 7819
          id: cord-296619-uhhndp0a
      author: Kondo, Yuki
       title: Coinfection with SARS-CoV-2 and influenza A virus
        date: 2020-07-01
       words: 1692
      flesch: 48
     summary: Coinfection with SARS-CoV-2 and other respiratory viruses has been described, but the reported frequency is variable. The clinical characteristics of patients with both COVID-19 and influenza virus infection were similar to those of COVID-19 cases.
    keywords: cov-2; covid-19; influenza; sars; virus
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        item: #3494 of 7819
          id: cord-296669-1md8j11e
      author: Li, Xin
       title: Factors Associated with Mental Health Results among Workers with Income Losses Exposed to COVID-19 in China
        date: 2020-08-04
       words: 3794
      flesch: 48
     summary: We enrolled 398 respondents and found a high prevalence of mental health symptoms among workers with income losses caused by COVID-19 in China. Thus, the prevalence rates of our participants who had severe mental symptoms of depression, anxiety, insomnia, and distress were 19.1%, 21.9%, 7.8%, and 25.9%, respectively.
    keywords: anxiety; covid-19; depression; health; income; insomnia
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        item: #3495 of 7819
          id: cord-296676-2anl2agl
      author: Goldberg, Michael F.
       title: Neuroradiologic manifestations of COVID-19: what the emergency radiologist needs to know
        date: 2020-08-21
       words: 4172
      flesch: 40
     summary: Retrospective observational study of brain magnetic resonance imaging findings in patients with acute SARS-CoV-2 infection and neurological manifestations SARS2-CoV-2 and stroke in a New York healthcare system Neurologic features in severe SARS-CoV-2 infection Large-vessel stroke as a presenting feature of Covid-19 in the young Cerebrovascular disease in COVID-19 SARS2-CoV-2 and stroke in a New York healthcare system Urgent carotid endarterectomy in a COVID-19 patient: standard approach with some adjustments Neurovascular complications in COVID-19 infection: case series Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical features and treatment of COVID-19 patients in Northeast Chongqing Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Analysis of risk factors for the thromboembolic events from 88 patients with COVID-19 pneumonia in Wuhan, China: a retrospective report Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19 Endothelial cell infection and endotheliitis in COVID-19 SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Uriel N (2020) COVID-19 and cardiovascular disease Large artery ischaemic stroke in severe acute respiratory syndrome (SARS) A report from a large medical system in New York City reported a 0.9% incidence of acute ischemic stroke (AIS) in 3556 hospitalized COVID-19 patients in the spring of 2020
    keywords: brain; case; cov-2; covid-19; disease; infection; patients; sars
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        item: #3496 of 7819
          id: cord-296682-ugffeegr
      author: Rahimi, Hoda
       title: A Comprehensive Review of Cutaneous Manifestations Associated with COVID-19
        date: 2020-07-05
       words: 1776
      flesch: 47
     summary: The second most frequent skin rash in COVID-19 patients was urticaria which appeared in 84 patients (18.6%). Cutaneous Lymphoid Hyperplasia Associated with Leishmania panamensis Infection Comment on Cutaneous manifestations in COVID-19: a first perspective by Recalcati S Morbilliform exanthem associated with COVID-19 A case of COVID-19 pneumonia in a young male with full body rash as a presenting symptom Manifestaciones cutaneas en contexto del brote actual de enfermedad por coronavirus 2019 Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases Comment on: Cutaneous manifestations in COVID-19: a first perspective.
    keywords: covid-19; disease; lesions; patients
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        item: #3497 of 7819
          id: cord-296692-t5p09le8
      author: Elgin, T.G.
       title: The changing landscape of SARS-CoV-2: Implications for the maternal-infant dyad
        date: 2020-09-07
       words: 5331
      flesch: 42
     summary: The development of international registries to enable risk profiling of COVID-19 positive pregnant mothers and/or their offspring may facilitate the development of enhanced mitigation strategies, medical treatments and effective vaccinations. The authors concluded increased risk of preterm birth in COVID-19 positive pregnant mothers.
    keywords: case; coronavirus; cov-2; covid-19; disease; evidence; health; mothers; neonatal; patients; pneumonia; sars; women
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        item: #3498 of 7819
          id: cord-296694-2js639bk
      author: Price, Laura C
       title: Thrombosis and COVID-19 pneumonia: the clot thickens!
        date: 2020-06-18
       words: 2397
      flesch: 34
     summary: Patients: Awareness of an Increased Prevalence High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Acute respiratory distress syndrome in critically ill patients with severe acute respiratory syndrome Analysis of deaths during the severe acute respiratory syndrome (SARS) epidemic in Singapore: challenges in determining a SARS diagnosis VTE Incidence and Risk Factors in Patients With Severe Sepsis and Septic Shock Endothelial cell infection and endotheliitis in COVID-19 Clinical and immunological features of severe and moderate coronavirus disease 2019 COVID-19 and its implications for thrombosis and anticoagulation Hypercoagulability of COVID-19 patients in Intensive Care Unit. In this edition of the European Respiratory Journal, Bompard et al. refine this further by describing a 50% cumulative incidence of pulmonary embolism (PE), diagnosed by CT-pulmonary angiogram (PA), in COVID-19 patients admitted to ICU in two hospitals of the University of Paris (ERJ ref Bompard).
    keywords: anticoagulation; coronavirus; covid-19; icu; patients; thrombosis
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        item: #3499 of 7819
          id: cord-296708-b37jcj4f
      author: Sagar, Rajesh
       title: Is it correct to estimate mental disorder through online surveys during COVID-19 pandemic?
        date: 2020-06-22
       words: 670
      flesch: 35
     summary: key: cord-296708-b37jcj4f authors: Sagar, Rajesh; Chawla, Nishtha; Sen, Mahadev Singh title: Is it correct to estimate mental disorder through online surveys during COVID-19 pandemic? date: 2020-06-22 journal: Psychiatry Res DOI: 10.1016/j.psychres.2020.113251 sha: doc_id: 296708 cord_uid: b37jcj4f nan COVID-19 infection hit the globe in late 2019 and spread widely across multiple nations to infect more than 5 million people across the world by this date. Many researchers are resorting to online surveys, abiding by physical distancing rules, to assess its psychological currently.
    keywords: covid-19; surveys
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        item: #3500 of 7819
          id: cord-296725-ecy0rie9
      author: Landau, Ruth
       title: Lessons Learned From First COVID-19 Cases in the United States
        date: 2020-04-20
       words: 672
      flesch: 27
     summary: Our case emphasizes that in labor and delivery units managing parturients from communities with a high prevalence of COVID-19 infection, in the absence of universal testing before cesarean delivery, all patients, even those initially asymptomatic on admission, should be treated as PUI when inducing general anesthesia. Neuraxial procedures in COVID-19 positive parturients: a review of current reports Novel Coronavirus (COVID-19) Anesthesia Resource Center Society for Obstetric Anesthesia and Perinatology (SOAP) Interim Considerations for Obstetric Anesthesia Care Related to COVID-19
    keywords: anesthesia; covid-19
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        item: #3501 of 7819
          id: cord-296746-j47306hx
      author: Chen, Fang-fang
       title: The characteristics and outcomes of 681 severe cases with COVID-19 in China
        date: 2020-07-08
       words: 2464
      flesch: 47
     summary: First, we found that age, CRP and LDH levels, CD3 counts, NLR, and acute myocardial injury were independently and negatively associated with death in severe COVID-19 patients. Age, Neutrophil-To-Lymphocyte Ratio (NLR), acute myocardial injury, and levels of C-reactive protein (CRP), lactate dehydrogenase (LDH), and CD3 T cells counts were independently and negatively associated with death, while arbidol and ribavirin were protective from death.
    keywords: cases; covid-19; injury; nlr; patients; survivors
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        item: #3502 of 7819
          id: cord-296773-5o4hr6ir
      author: Zeneli, A.
       title: Mitigating strategies and nursing response for cancer care management during the COVID‐19 pandemic: an Italian experience
        date: 2020-10-02
       words: 4702
      flesch: 33
     summary: This enabled us to provide planned cancer treatments and diagnostic To minimize the overall risk of poor outcomes in cancer patients treated in our centre by ensuring treatment continuity and by protecting patients, caregivers and healthcare professionals from the SARS-CoV-2 infection Patient, caregiver and employee safety, patient health outcomes, use of resources Adopted strategies and instruments for achieving goals Risk assessment to screen those with flu-like symptoms and refer them to their general practitioner for early communication, isolation and treatment for COVID-19 to prevent severe disease; telephone triage of patients before planning their visit to hospital; triaging patients and their caregivers before their access to cancer services; Continuity of essential services, appropriate case management Communication instruments An ad hoc computerized triage tool to support healthcare professionals in the decision-making process and in documenting their evaluations (Fig. 1) Establishment of a separate and dedicated pathway inside the hospital for the clinical and instrumental assessment of suspected COVID-19 cases; creation of separate itineraries within the hospital for administration staff and for healthcare professionals and patients (Fig. 2) ; reorganization of waiting rooms and common areas such as cafeterias and meeting rooms to favour social distancing; dedicated and easily noticeable stations in each cancer service containing PPEs and ready-to-use kits for surface cleaning and disinfection of reusable devices and surfaces between patients; controlling the access of lay caregivers accompanying patients to the healthcare environment to limit the spread of the virus by promoting social distancing and by reducing the number of people inside the hospital building; introduction of smart working for administration staff, procedures whilst maintaining a safe environment for patients and healthcare professionals. This was obviously a sensitive issue because of the complex needs of cancer patients.
    keywords: cancer; covid-19; emergency; healthcare; nurses; nursing; pandemic; patients; policies; professionals; response
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        item: #3503 of 7819
          id: cord-296801-19p33j65
      author: Hagge, Daniel
       title: Chancen und Einsatzmöglichkeiten von Telemedizin in der Hals‑, Nasen- und Ohrenheilkunde bei der Bekämpfung von SARS-COV-2: Narratives Review
        date: 2020-04-16
       words: 1514
      flesch: 39
     summary: Unabhängig von der COVID-19-Pandemie kann die Verwendung von Telemedizin allgemein 3 große Vorteile, unabhängig von der jeweiligen Fachdisziplin, bringen: Reduzierte Morbidität und Mortalität mit folglich geringeren Kosten für das Gesundheitssystem durch Früherkennung von schweren Erkrankungen, Einsparungen an Fahrtkosten, Gesundheitsausgaben und Zeit durch Vermeidung unnötiger Arztbesuche sowie effiziente Nutzung von Facharztressourcen key: cord-296801-19p33j65 authors: Hagge, Daniel; Knopf, Andreas; Hofauer, Benedikt title: Chancen und Einsatzmöglichkeiten von Telemedizin in der Hals‑, Nasen- und Ohrenheilkunde bei der Bekämpfung von SARS-COV-2: Narratives Review date: 2020-04-16 journal: HNO DOI: 10.1007/s00106-020-00864-7 sha: doc_id: 296801 cord_uid: 19p33j65 INTRODUCTION:
    keywords: covid-19; dem; der; die; mit; patienten; patients; telemedicine; und; von; werden
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        item: #3504 of 7819
          id: cord-296803-tde8k4kr
      author: Lundin, Rebecca
       title: Gender-based violence during the COVID-19 pandemic response in Italy
        date: 2020-09-07
       words: 1503
      flesch: 45
     summary: These findings are in keeping with data published by the Italian National Institute of Statistics (ISTAT), indicating a 59% increase in calls to a hotline for GBV victims between 1 March and 16 April 2020 compared to the same period in 2019, with the vast majority of calls (93.2%) made by women with a longterm history of GBV [10] . China, Spain, and the UK have created and widely distributed guidelines for assisting GBV victims during the COVID-19 pandemic, and Chile has developed e-learning courses and counseling materials to prevent GBV
    keywords: covid-19; data; gbv; health; violence; women
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        item: #3505 of 7819
          id: cord-296806-pep4vlj1
      author: Rotulo, Gioacchino Andrea
       title: Giant Urticaria and Acral Peeling in a Child with COVID-19
        date: 2020-10-21
       words: 232
      flesch: 39
     summary: Several clinical cases of suspected COVID-19 with skin involvement have been described in pediatric age, but most of them were unconfirmed cases (Appendix). key: cord-296806-pep4vlj1 authors: Rotulo, Gioacchino Andrea; Signa, Sara; Rosina, Silvia; Pastorino, Carlotta; Bondi, Elisabetta; Maghnie, Mohamad title: Giant Urticaria and Acral Peeling in a Child with COVID-19 date: 2020-10-21 journal: J Pediatr DOI: 10.1016/j.jpeds.2020.10.039 sha: doc_id: 296806 cord_uid: pep4vlj1 nan The fever disappeared quickly, lasting only 24 hours.
    keywords: covid-19
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        item: #3506 of 7819
          id: cord-296811-zelkkw1f
      author: Rodríguez-Padial, Luis
       title: El riesgo competitivo puede explicar en gran medida la disminución de los ingresos por enfermedad cardiovascular aguda durante la pandemia de COVID-19
        date: 2020-07-30
       words: 949
      flesch: 43
     summary: Es decir, los pacientes mayores, los de mayor mortalidad en la COVID-19, son los que no han ido al hospital, probablemente por haberse visto afectados y haber fallecido por dicha enfermedad. competitivos con el contagio y la gravedad de la COVID-19 2 , lo cierto es que parece haberse asumido como causa más probable que los pacientes hayan evitado acudir a los servicios de urgencias por miedo a la pandemia.
    keywords: con; del; los; por; que
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        item: #3507 of 7819
          id: cord-296881-2g81sjnl
      author: Nabil, Ahmed
       title: Current coronavirus (SARS-CoV-2) epidemiological, diagnostic and therapeutic approaches: An updated review until June 2020
        date: 2020-07-20
       words: 4818
      flesch: 30
     summary: COVID-19 patients observed to have a dysfunction in the renin-angiotensin system (RAS). MSCs transplantation improved the outcome of COVID-19 patients.
    keywords: acute; cases; cells; coronavirus; cov-2; covid-19; disease; effects; infection; patients; potential; sars; treatment
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        item: #3508 of 7819
          id: cord-296888-z5x6zkht
      author: Hailay, Abrha
       title: The burden, admission, and outcomes of COVID-19 among asthmatic patients in Africa: protocol for a systematic review and meta-analysis
        date: 2020-09-04
       words: 2766
      flesch: 43
     summary: Describe planned method of extracting data from reports (e.g., piloting forms, done independently, in duplicate), any processes for obtaining and confirming data from investigators Data items 12 List and define all variables for which data will be sought (e.g., PICO items, funding sources), any pre-planned data assumptions and simplifications Outcomes and prioritization 13 List and define all outcomes for which data will be sought, including prioritization of main and additional outcomes, with rationale Risk of bias in individual studies 14 Describe anticipated methods for assessing risk of bias of individual studies, including whether this will be done at the outcome or study level, or both; state how this information will be used in data synthesis Describe criteria under which study data will be quantitatively synthesized 15b If data are appropriate for quantitative synthesis, describe planned summary measures, methods of handling data, and methods of combining data from studies, including any Studies that have not clarified the requirements for the COVID-19 outcome level; studies that have not been conducted in humans, qualitative studies, studies that lack valid data required to determine the outcome will not be included. A tool developed by Hoy et al. for prevalence studies will be used to evaluate the likelihood of bias and quality of studies included in this review [20] .
    keywords: covid-19; data; outcome; patients; review; studies; study
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        item: #3509 of 7819
          id: cord-296936-5gkx4jxa
      author: An, M. H.
       title: Treatment Response to Hydroxychloroquine and Antibiotics for mild to moderate COVID-19: a retrospective cohort study from South Korea
        date: 2020-07-07
       words: 3791
      flesch: 42
     summary: Based on a recent study from China, about 80% of COVID-19 patients show non-severe symptoms(3) The authors reviewed the electronic medical records of included patients and collected epidemiological, clinical, historical, laboratory, and treatment outcomes data.
    keywords: covid-19; hydroxychloroquine; license; patients; preprint; study; treatment
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        item: #3510 of 7819
          id: cord-296950-9dldbs6o
      author: El-Zein, Rayan S
       title: COVID-19-associated meningoencephalitis treated with intravenous immunoglobulin
        date: 2020-09-06
       words: 1842
      flesch: 38
     summary: The CSF PCR for SARS-CoV-2 was negative, yet this could not exclude COVID-19 meningoencephalitis. Large studies pertaining to the incidence, diagnostics, and therapeutics of COVID-19 neurologic manifestations remain lacking.
    keywords: cov-2; covid-19; csf; day; patient; sars
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        item: #3511 of 7819
          id: cord-296986-8fuj072z
      author: Kumar, Manish
       title: A chronicle of SARS-CoV-2: Part-I - Epidemiology, diagnosis, prognosis, transmission and treatment
        date: 2020-05-15
       words: 4473
      flesch: 40
     summary: The Lancet infectious diseases Presumed asymptomatic carrier transmission of COVID-19 Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum Will coronavirus pandemic diminish by summer The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro Human immunopathogenesis of severe acute respiratory syndrome (SARS) Features, evaluation and treatment coronavirus (COVID-19) Coronavirus Disease 2019 (COVID-19) Interspecies transmission and emergence of novel viruses: lessons from bats and birds The effects of temperature and relative humidity on the viability of the SARS coronavirus Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Use of convalescent plasma therapy in SARS patients in Hong Kong Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia Statens Serum Institut. The Lancet infectious diseases Radiologic pattern of disease in patients with severe acute respiratory syndrome: the Toronto experience Coronaviruses post-SARS: update on replication and pathogenesis Another decade, another coronavirus The novel coronavirus originating in Wuhan, China: challenges for global health governance Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic Dysregulation of immune response in patients with COVID-19 in Wuhan, China Declares Global Emergency as Wuhan Coronavirus Spreads.
    keywords: coronavirus; cov-2; covid-19; disease; infection; influenza; novel; patients; sars; temperature; transmission
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        item: #3512 of 7819
          id: cord-297001-4g3wb8qi
      author: Tal, Shir
       title: Venous Thromboembolism Complicated with COVID-19: What Do We Know So Far?
        date: 2020-05-12
       words: 4638
      flesch: 44
     summary: In view of the high thromboembolic risk in patients with COVID-19 despite anticoagulation treatment [14] , and in view of the thrombotic coagulopathy and extremely high D-dimers with no evidence of clinical bleeding in COVID-19 patients, some institutes like our own recommend considering higher prophylactic doses of anticoagulation such as enoxaparin 0.5 mg/kg b.i.d. or enoxaparin 1mg/kg once daily. In addition, antiphospholipid antibodies that can arise transiently in patients with critical illness and various infections may possibly develop among COVID-19 patients as well.
    keywords: coronavirus; covid-19; diagnosis; dimer; disease; patients; risk; treatment; vte
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        item: #3513 of 7819
          id: cord-297010-imciixde
      author: Babayeva, Mariana
       title: Repurposing Drugs for COVID-19: Pharmacokinetics and Pharmacogenomics of Chloroquine and Hydroxychloroquine
        date: 2020-10-23
       words: 7101
      flesch: 43
     summary: Another open-label non-randomized clinical trial with 36 COVID-19 patients demonstrated that hydroxychloroquine treatment resulted in viral load reduction/disappearance in the patients. Mechanisms underlying variability in drug concentrations and therapeutic response with chloroquine and hydroxychloroquine in mediating beneficial and adverse effects of chloroquine and hydroxychloroquine were reviewed and analyzed.
    keywords: chloroquine; concentrations; covid-19; cyp2c8; dose; drug; hcq; hydroxychloroquine; malaria; medications; metabolism; patients; plasma; treatment
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        item: #3514 of 7819
          id: cord-297013-0ykz2raz
      author: Agarwal, D. K.
       title: Alternative Approaches for Modelling COVID-19:High-Accuracy Low-Data Predictions
        date: 2020-07-25
       words: 4313
      flesch: 57
     summary: Interpretation: We have shown that curve-fitting and machine-learning methods applied on reported COVID-19 data almost perfectly reproduce the results of far more complex and data-intensive epidemiological models. Interpretation: We have shown that curve-fitting and machine-learning methods applied on reported COVID-19 data almost perfectly reproduce the results of far more complex and data-intensive epidemiological models.
    keywords: cases; countries; covid-19; data; license; number; preprint
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        item: #3515 of 7819
          id: cord-297029-b38sm4y9
      author: Murillo-Zamora, Efrén
       title: Male gender and kidney illness are associated with an increased risk of severe laboratory-confirmed coronavirus disease
        date: 2020-09-16
       words: 2958
      flesch: 45
     summary: In China, there was a higher frequency for severe patients to be current smokers (16.9% vs. 11.8%), however, no association analysis was performed [23] . In multiple analysis, male gender (RR = 1.13, 95% CI 1.06–1.20), advanced age ([reference: 15–29 years old] 30–44, RR = 1.02, 95% CI 0.94–1.11; 45–59, RR = 1.26, 95% CI 1.15–1.38; 60 years or older, RR = 1.44, 95% CI 1.29–1.60), chronic kidney disease (RR = 1.31, 95% CI 1.04–1.64) and thoracic pain (RR = 1.16, 95% CI 1.10–1.24) were associated with an increased risk of severe disease.
    keywords: covid-19; disease; patients; risk; study
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        item: #3516 of 7819
          id: cord-297093-ld89vmct
      author: Clark, Kristina E N
       title: Safety of intravenous Anakinra in COVID-19 with evidence of hyperinflammation, a case series
        date: 2020-08-04
       words: 3245
      flesch: 41
     summary: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical features of patients infected with 2019 novel coronavirus in Wuhan The cytokine release syndrome (CRS) of severe COVID-19 and Interleukin-6 receptor (IL-6R) antagonist Tocilizumab may be the key to reduce the mortality COVID-19: Immunology and treatment options Pathogenic T cells and inflammatory monocytes incite inflammatory storm in severe COVID-19 patients A Dynamic Immune Response Shapes COVID-19 Progression. Our aim is to report our experience on the beneficial effects of intravenous anakinra in patients with SARS-CoV-2 and evidence of hyperinflammation.
    keywords: anakinra; covid-19; day; days; ferritin; patients; use
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        item: #3517 of 7819
          id: cord-297127-nhgm09db
      author: Hasseli, Rebecca
       title: National registry for patients with inflammatory rheumatic diseases (IRD) infected with SARS-CoV-2 in Germany (ReCoVery): a valuable mean to gain rapid and reliable knowledge of the clinical course of SARS-CoV-2 infections in patients with IRD
        date: 2020-09-02
       words: 4096
      flesch: 40
     summary: With recruitment of more patients in the near future the trend of lower hospitalisation rates in patients with IRD treated with bDMARDs compared to those treated with csDMARDs will be further investigated. (D) Distribution of comorbidities (in %): 41% had no comorbidities, 37% suffered from AHT, 15% from other relevant comorbidities, 13% from CVD, 9% each from bronchial asthma and DM, 8% each from COPD and CRF, 6% from OSP, 5% from cancer/history of cancer, 2% from ILD, 1% from PAH and 15% from other relevant comorbidities, 30% had more than two comorbidities.
    keywords: course; cov-2; covid-19; disease; infection; ird; patients; risk; sars
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        item: #3518 of 7819
          id: cord-297132-lhfa9fl5
      author: Aghagoli, Ghazal
       title: Neurological Involvement in COVID-19 and Potential Mechanisms: A Review
        date: 2020-07-13
       words: 5953
      flesch: 31
     summary: Clin Basic Evid Detection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndrome Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways Neuroinvasion by human respiratory coronaviruses Activation of glial cells by human coronavirus OC43 infection Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan Detection of coronavirus RNA and antigen in multiple sclerosis brain Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 Human coronavirus OC43 infection induces chronic encephalitis leading to disabilities in BALB/C mice Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-α Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission Inhibition of SARS-CoV-2 infections in engineered human tissues using clinical-grade soluble human ACE2 Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. Awareness of the possible neurological manifestations in COVID-19 patients is of utmost importance to assist providers in the recognition, treatment, and management of potentially life-threatening neurologic complications.
    keywords: ace2; acute; brain; cells; clinical; coronavirus; cov-2; covid-19; human; infection; injury; patients; sars
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        item: #3519 of 7819
          id: cord-297157-16ciqu9w
      author: Mamun, Mohammed A.
       title: First COVID-19 suicide case in Bangladesh due to fear of COVID-19 and xenophobia: Possible suicide prevention strategies
        date: 2020-04-07
       words: 1170
      flesch: 40
     summary: In extreme cases, such mental health issues can lead to suicidal behaviors (e.g., suicidal ideation, suicide attempts, and actual suicide). We would suggest there is an urgent need to carry out a nationwide epidemiological study to determine the level fear, worry, and helplessness, as well as other associated issues concerning mental health in relation to COVID-19.
    keywords: covid-19; suicide
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        item: #3520 of 7819
          id: cord-297209-84gs67bn
      author: Livanos, A. E.
       title: Gastrointestinal involvement attenuates COVID-19 severity and mortality
        date: 2020-09-09
       words: 7533
      flesch: 45
     summary: In a fourth cohort of COVID-19 patients in which GI biopsies were obtained, we identified severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) within small intestinal enterocytes for the first time in vivo but failed to obtain culturable virus. Importantly, mortality was significantly 185 lower in COVID-19 patients with GI symptoms (15.7%) than those without GI symptoms (31.0%; 186 p<0.0001 Fisher's exact test)
    keywords: author; copyright; covid-19; funder; holder; license; medrxiv preprint; patients; peer; preprint; review; september; symptoms; version
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        item: #3521 of 7819
          id: cord-297210-b8bl5vq5
      author: Leask, Andrew
       title: COVID-19: is fibrosis the killer?
        date: 2020-05-13
       words: 483
      flesch: 44
     summary: COVID-19 patients developed acute respiratory distress syndrome (ARDS), a disease that is characterized by rapid onset fibrosis. These data strongly imply that not only is pulmonary fibrosis a comorbidity for COVID-19, but that it may be the cause of mortality for COVID-19.
    keywords: covid-19; patients
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        item: #3522 of 7819
          id: cord-297213-r5ulw2n1
      author: Lim, Michael Anthonius
       title: The Danger of Sedentary Lifestyle in Diabetic and Obese People During the COVID-19 Pandemic
        date: 2020-10-19
       words: 956
      flesch: 24
     summary: Michael Anthonius Lim https://orcid.org/0000-0001 -7631-6835 Raymond Pranata https://orcid.org/0000-0003-3998-6551 Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia -A systematic review, meta-analysis, and meta-regression: diabetes and COVID-19 Hypertension is associated with increased mortality and severity of disease in COVID-19 pneumonia: a systematic review, meta-analysis and meta-regression Impact of cerebrovascular and cardiovascular diseases on mortality and severity of COVID-19 -Systematic review, meta-analysis, and meta-regression Effect of chronic obstructive pulmonary disease and smoking on the outcome of COVID-19 Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysis Elevated N-terminal pro-brain natriuretic peptide is associated with increased mortality in patients with COVID-19: systematic review and meta-analysis Multiorgan failure with emphasis on acute kidney injury and severity of COVID-19: systematic review and meta-analysis C-reactive protein, procalcitonin, D-dimer, and ferritin in severe coronavirus disease-2019: a metaanalysis The Importance of COVID-19 Prevention and Containment in Hemodialysis Unit Does high cardiorespiratory fitness confer some protection against pro-inflammatory responses after infection by SARS-CoV-2? Body mass index and outcome in patients with COVID-19: a dose-response meta-analysis Coronavirus disease-2019: a tocsin to our aging, unfit, corpulent, and immunodeficient society Potential role of telemedicine in solving ST-segment elevation dilemmas in remote areas during the COVID-19 pandemic Out-of-hospital cardiac arrest prognosis during the COVID-19 pandemic Effect of heart failure on the outcome of COVID-19 -A meta analysis and systematic review How much is too much? key: cord-297213-r5ulw2n1 authors: Lim, Michael Anthonius; Pranata, Raymond title: The Danger of Sedentary Lifestyle in Diabetic and Obese People During the COVID-19 Pandemic date: 2020-10-19 journal: Clin Med Insights Endocrinol Diabetes DOI: 10.1177/1179551420964487 sha: doc_id: 297213 cord_uid: r5ulw2n1 nan To the Editor, The incidence of Coronavirus Disease 2019 (COVID-19) is growing worldwide and people with certain health conditions are likely to develop more severe infections.
    keywords: covid-19; meta; risk
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        item: #3523 of 7819
          id: cord-297217-pe6mehjv
      author: Simpson, A. Hamish R. W.
       title: COVID-19: potential transmission through aerosols in surgical procedures and blood products
        date: 2020-07-23
       words: 1327
      flesch: 33
     summary: 15 in addition, in conjunction with public Health england, they have recommended that ventilation in both laminar flow and conventionally ventilated theatres should remain fully on during surgical procedures where patients may have CoVid-19 infection, as the rapid dilution of these aerosols by operating theatre ventilation will help to protect operating room staff. Wong et al 25 concur with the view that a high frequency (> 25 per hour) of air changes will rapidly reduce the viral load in the operating theatre, suggesting that in terms of minimizing risk to the patient of implant infection and to the staff of CoVid-19 infection, this is a pragmatic way to reduce the risk of aerosol transmission.
    keywords: blood; covid-19; procedures; risk
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        item: #3524 of 7819
          id: cord-297218-yct9fu8r
      author: Hyland, Kelly A.
       title: Behavioral and psychosocial responses of people receiving treatment for advanced lung cancer during the COVID‐19 pandemic: a qualitative analysis
        date: 2020-06-16
       words: 1528
      flesch: 41
     summary: Greater loneliness has been associated with worse quality of life and greater depressive symptomology in lung cancer patients, highlighting the potential negative consequences of COVID-19-related isolation for patient wellbeing. Importantly, qualitative analysis highlights the unique challenges and resilience of advanced cancer patients during COVID-19.
    keywords: cancer; covid-19; participants; patients
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        item: #3525 of 7819
          id: cord-297236-wnuvofwr
      author: Zhang, Si
       title: SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19
        date: 2020-09-04
       words: 10433
      flesch: 44
     summary: Further, we provided evidence suggesting that the MAPK pathway, downstream of ACE2, mediates the potentiating role of SARS-CoV-2 on platelet activation, and that platelet ACE2 expression decreases following SARS-COV-2 stimulation. Flow cytometry was used to evaluate platelet activity in COVID-19 patients, non-COVID-19 patients and healthy volunteers, and to evaluate platelet activity and ACE2 and TMPRSS2 expression in SARS-CoV-2 virus or Spike protein treated healthy platelets and leukocyteplatelet aggregates.
    keywords: ace2; activation; cov-2; covid-19; donors; fig; figure; file; human; mice; online; patients; platelets; protein; sars; spike; type
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        item: #3526 of 7819
          id: cord-297241-ajy2wi51
      author: Katz, Carmit
       title: Invisible children and non-essential workers: Child protection during COVID-19 in Israel according to policy documents and media coverage
        date: 2020-10-06
       words: 4678
      flesch: 44
     summary: Moreover, the study points to the heightened threat to at-risk children due to inadequate policies, and to the urgent need to develop child protection policies in order to avoid further risk in future global crises. The current study examines the protection of Israeli children from maltreatment during .
    keywords: children; covid-19; documents; government; israel; media; policy; risk
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        item: #3527 of 7819
          id: cord-297286-bo6pr34s
      author: None
       title: Medical conferences in the post-COVID world: a challenge, and an opportunity
        date: 2020-05-16
       words: 1305
      flesch: 49
     summary: Many other conferences have been similarly affected; no one yet knows when face-to-face conferences can safely resume, and what restrictions may still be necessary when they do. key: cord-297286-bo6pr34s authors: nan title: Medical conferences in the post-COVID world: a challenge, and an opportunity date: 2020-05-16 journal: Eur Radiol DOI: 10.1007/s00330-020-06933-3 sha: doc_id: 297286 cord_uid: bo6pr34s nan The current COVID-19 pandemic has struck humanity like a biblical or historical plague, with a rapidity rarely seen even during those previous events.
    keywords: covid-19; disease; pandemic; radiology
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        item: #3528 of 7819
          id: cord-297323-l3f12hg4
      author: Amor, Sandra
       title: Innate immunity during SARS‐CoV‐2: evasion strategies and activation trigger hypoxia and vascular damage
        date: 2020-09-26
       words: 4990
      flesch: 26
     summary: All rights reserved the Acute COVID-19 Cardiovascular Syndrome Neurological associations of COVID-19 The Proteins of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2 or n-COV19), the Cause of COVID-19 Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding 3D Models of glycosylated SARS-CoV-2 spike protein suggest challenges and opportunities for vaccine development Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy Neuropilin-1 is a host factor for SARS-CoV-2 infection Accessory proteins of SARS-CoV and other coronaviruses Extreme genomic CpG deficiency in SARS-CoV-2 and evasion of host antiviral defense Identification of Residues of SARS-CoV nsp1 That Differentially Affect Inhibition of Gene Expression and Antiviral Signaling Severe Acute Respiratory Syndrome Coronavirus Evades Antiviral Signaling: Role of nsp1 and Rational Design of an Attenuated Strain Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation Like many viruses, SARS‐CoV‐2 has evolved strategies to circumvent innate immune detection including low CpG levels in the genome, glycosylation to shield essential elements including the receptor binding domain, RNA shielding and generation of viral proteins that actively impede anti‐viral interferon responses.
    keywords: article; cell; copyright; coronavirus; cov-2; covid-19; host; infection; protein; response; rights; rna; sars; syndrome
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        item: #3529 of 7819
          id: cord-297327-19dfgfz6
      author: Drożdżal, Sylwester
       title: COVID-19: Pain Management in Patients with SARS-CoV-2 Infection—Molecular Mechanisms, Challenges, and Perspectives
        date: 2020-07-20
       words: 5681
      flesch: 37
     summary: This narrative review summarizes current knowledge regarding challenges associated with pain assessment and management in COVID-19 patients. It is believed that myalgia in COVID-19 patients might reflect the generalized inflammation and cytokine response [34] .
    keywords: coronavirus; cov-2; covid-19; disease; effects; infection; management; opioids; pain; patients; sars; symptoms; treatment; use
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        item: #3530 of 7819
          id: cord-297333-fyn2xzfw
      author: Inchingolo, Riccardo
       title: The Diagnosis of Pneumonia in a Pregnant Woman with COVID-19 Using Maternal Lung Ultrasound
        date: 2020-04-28
       words: 510
      flesch: 23
     summary: We report our experience on lung ultrasound examination in the diagnosis of Sars-Cov-2 pneumonia in a pregnant woman. We report our experience on lung ultrasound examination in the diagnosis of Sars-Cov-2 59 pneumonia in a pregnant woman.
    keywords: lung; ultrasound
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        item: #3531 of 7819
          id: cord-297362-mhtvrn0c
      author: Wu, Xian-rui
       title: Practice Patterns of Colorectal Surgery During the COVID-19 Pandemic
        date: 2020-11-05
       words: 1497
      flesch: 47
     summary: In general, there was a high agreement on the criteria for emergent colorectal surgery. The main indications for emergent colorectal surgery were bowel obstruction (n = 284, 78.2%) and bowel perforation (n = 237, 65.3%).
    keywords: covid-19; pandemic; surgery
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        item: #3532 of 7819
          id: cord-297365-11es4w0u
      author: Peng, Hui
       title: Coronavirus Disease 2019 in Children: Characteristics, Antimicrobial Treatment, and Outcomes
        date: 2020-05-07
       words: 1697
      flesch: 52
     summary: Young children are more dependent on their family members and infants are not suitable for wearing masks, which may explain why children younger than 2 years are the most vulnerable group to COVID-19. On February 19, arbidol was included in A Case Series of children with 2019 novel coronavirus infection: clinical and epidemiological features Pediatric Branch of Hubei Medical Association; Pediatric Branch of Wuhan Medical Association Recommendation for the diagnosis and treatment of novel coronavirus infection in children in Hubei Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus Cardiovascular Complications in Patients with COVID-19: Consequences of Viral Toxicities and Host Immune Response Clinical Characteristics of Children with Coronavirus Disease COVID-19 epidemic: Disease characteristics in children Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study Epidemiology of COVID-19 Among Children in China COVID-19 in Children: Initial Characterization of the Pediatric Disease Treatment of SARS with human interferons Treatment efficacy analysis of traditional Chinese medicine for novel coronavirus pneumonia (COVID-19): an empirical study from Wuhan Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study Clinical Features of 69 Cases with Coronavirus Disease Arbidol combined with LPV/r versus LPV/r alone against Corona Virus Disease 2019:a retrospective cohort study Arbidol monotherapy is superior to lopinavir/ritonavir in treating COVID-19
    keywords: cases; children; covid-19; patients
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        item: #3533 of 7819
          id: cord-297368-ju6r1rf1
      author: Moradi, Soroush
       title: Prevalence of coronavirus disease 2019 in rheumatic patients and evaluation of the effect of disease-modifying anti-rheumatic drugs
        date: 2020-10-31
       words: 2926
      flesch: 46
     summary: As mentioned earlier, some drugs which are commonly used in the treatment of RD has also been considered as potential candidates for COVID-19 treatment, based on recent studies, including chloroquine, hydroxychloroquine, leflunomide, tumor necrosis factor (TNF) inhibitors, Janus kinase (JAK) inhibitors, interleukin antagonists, and even corticosteroids First update Rheumatologists' perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies Chloroquine as a potential treatment and prevention measure for the 2019 novel coronavirus: a review COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression Role of chloroquine and hydroxychloroquine in the treatment of COVID-19 infection-a systematic literature review Wegener's granulomatosis: a rare, chronic and multisystem disease Clinical features of patients infected with 2019 novel coronavirus in Should patients stop their biologic treatment during the COVID-19 pandemic Author contributions All authors contributed equally to this study.
    keywords: control; covid-19; group; patients; rps; study
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        item: #3534 of 7819
          id: cord-297378-quyehjr1
      author: Hong, Yan
       title: The Impact of COVID-19 on Tourist Satisfaction with B&B in Zhejiang, China: An Importance–Performance Analysis
        date: 2020-05-25
       words: 7860
      flesch: 50
     summary: Our paper is among one of the first studies to investigate the impact of COVID-19 on tourist satisfaction with B&Bs in China. Our paper is among one of the first studies to investigate the impact of COVID-19 on tourist satisfaction with B&B in China.
    keywords: analysis; b&b; b&bs; china; covid-19; impact; importance; industry; ipa; performance; satisfaction; tourism; tourists; zhejiang
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        item: #3535 of 7819
          id: cord-297384-0urbjy5p
      author: Bal, Irene A.
       title: The Balance of Roles: Graduate Student Perspectives during the COVID-19 Pandemic
        date: 2020-08-09
       words: 1810
      flesch: 62
     summary: Graduate students juggle a variety of roles and had to quickly adjust. As an instructional designer and graduate student, plans for the next semesters are undecided and erratic… I am still taking it one hour at a time, one day at a time.
    keywords: dissertation; learning; pandemic; students; time
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        item: #3536 of 7819
          id: cord-297395-5r4fxcuq
      author: Rezende, Leandro F. M.
       title: Adults at high-risk of severe coronavirus disease-2019 (Covid-19) in Brazil
        date: 2020-05-15
       words: 2325
      flesch: 49
     summary: We included risk factors for severe Covid-19 based on currently available information from clinical studies and expertise [2] [3] [4] Criterion 1 included first identified and established risk factors for severe Covid-19 such as age ≥ 65 years or medical diagnosis of cardiovascular disease, diabetes, hypertension, chronic respiratory disease, cancer or stroke.
    keywords: adults; covid-19; disease; factors; prevalence; risk
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        item: #3537 of 7819
          id: cord-297396-r1p7xn3a
      author: Ng, Ming-Yen
       title: Development and Validation of Risk Prediction Models for COVID-19 Positivity in a Hospital Setting
        date: 2020-09-15
       words: 3254
      flesch: 47
     summary: Reverse transcription polymerase chain reaction (RT-PCR) is regarded as a vital tool in identifying the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and quarantining COVID-19 patients to prevent further spread of the disease 4 . As yet, the data which supports these strategies are predominantly based on data of COVID-19 patients 12, 13 but without comparisons to patients with other conditions and symptoms overlapping with COVID-19 (eg. fever, shortness of breath, cough).
    keywords: contact; covid-19; cxr; model; nomograms; patients; points; step
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        item: #3538 of 7819
          id: cord-297413-gw0z23z9
      author: Jalili, M.
       title: Burnout among healthcare professionals during COVID-19 pandemic: a cross-sectional study
        date: 2020-06-13
       words: 4889
      flesch: 50
     summary: The results of multiple logistic regression analysis of different variables to detect their impact on the development of high burnout levels have been presented in Table 4 . In our study, more than 55% of the nurses experienced high burnout during the COVID-19 pandemic.
    keywords: burnout; covid-19; funder; healthcare; medrxiv; preprint; review; study
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        item: #3539 of 7819
          id: cord-297414-zq16s9ud
      author: Koh, Adrian H. C.
       title: What COVID-19 has taught us: lessons from around the globe
        date: 2020-06-13
       words: 1780
      flesch: 43
     summary: This is especially important for patients at higher risk of contracting the virus, such as elderly patients, and those who are immunocompromised such as diabetic patients. Tele-ophthalmology refers to the practice of caring for patients remotely when the ophthalmologist and patient are not physically present with each other [9] .
    keywords: care; covid-19; health; ophthalmology; pandemic; patients; telemedicine
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        item: #3540 of 7819
          id: cord-297425-vcqqssm8
      author: Aries, James A.
       title: Clinical Outcome of Coronavirus Disease 2019 in Haemato‐oncology Patients
        date: 2020-05-18
       words: 1404
      flesch: 40
     summary: The initial reports from China show that patients with cancer are over‐represented among individuals who develop severe Covid‐19 after contracting the virus.(4) Patients with haematological malignancies are expected to be at increased risk of adverse outcomes from this viral infection, due being immunosuppressed as a consequence of the underlying cancer, and from the effects of therapy. (3) The initial reports from China show that patients with cancer are over-represented among individuals who develop severe Covid-19 after contracting the virus.(4) Patients with haematological malignancies are expected to be at increased risk of adverse outcomes from this viral infection, due being immunosuppressed as a consequence of the underlying cancer, and from the effects of therapy.
    keywords: cancer; covid-19; disease; patients
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        item: #3541 of 7819
          id: cord-297432-2edncbgn
      author: Helleberg, Marie
       title: Persistent COVID-19 in an Immunocompromised Patient Temporarily Responsive to Two Courses of Remdesivir Therapy
        date: 2020-07-23
       words: 2399
      flesch: 43
     summary: This pattern was repeated during and after a second course of remdesivir treatment. The role of ongoing viral infection versus a secondary hyperreactive immune response in the aftermath of viral replication for the development of severe COVID-19 is not completely understood [6] .
    keywords: covid-19; day; infection; patients; remdesivir; sars; treatment
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        item: #3542 of 7819
          id: cord-297477-o7kydesb
      author: Das, Ashis Kumar
       title: Epidemiology of COVID-19 and Predictors of Recovery in the Republic of Korea
        date: 2020-07-30
       words: 1709
      flesch: 56
     summary: MATERIALS AND METHODS: Using publicly available data for confirmed COVID-19 cases from the Korea Centers for Disease Control and Prevention from January 20, 2020, to April 30, 2020, we undertook descriptive analyses of cases stratified by sex, age group, place of exposure, date of confirmation, and province. Our study adds to the very limited evidence base on potential predictors of recovery among confirmed COVID-19 cases.
    keywords: cases; covid-19; korea; recovery
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        item: #3543 of 7819
          id: cord-297513-fxap5sw4
      author: Liu, S. H.
       title: Time courses of COVID-19 infection and local variation in socioeconomic and health disparities in England
        date: 2020-05-29
       words: 3507
      flesch: 41
     summary: The higher case trajectory cluster (79 local authorities) had higher population density (p<0.001), higher proportion of Black and Asian residents (p=0.03; p=0.02), higher multiple deprivation scores (p<0.001), a lower proportions of older adults (p=0.005), and higher preventable mortality rates (p=0.03). key: cord-297513-fxap5sw4 authors: Liu, S. H.; Liu, B.; Li, Y.; Norbury, A. title: Time courses of COVID-19 infection and local variation in socioeconomic and health disparities in England date: 2020-05-29 journal: nan DOI: 10.1101/2020.05.29.20116921 sha: doc_id: 297513 cord_uid: fxap5sw4 Objective: To identify factors associated with local variation in the time course of COVID-19 case burden in England.
    keywords: case; covid-19; data; health; license; medrxiv; preprint
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        item: #3544 of 7819
          id: cord-297517-w8cvq0m5
      author: Toğaçar, Mesut
       title: COVID-19 detection using deep learning models to exploit Social Mimic Optimization and structured chest X-ray images using fuzzy color and stacking approaches
        date: 2020-05-06
       words: 4683
      flesch: 54
     summary: We evaluate the various stages for dataset images and determine that these values are the most efficient of the dataset. For this study, we combined two publicly accessible databases consisting of COVID-19 images.
    keywords: approach; classification; covid-19; dataset; images; learning; model; pneumonia; step; technique
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        item: #3545 of 7819
          id: cord-297518-6y2uzcde
      author: Leulseged, T. W.
       title: Determinants of Developing Symptomatic Disease in Ethiopian COVID-19 Patients
        date: 2020-10-13
       words: 3325
      flesch: 44
     summary: The aim of the study was to assess the determinants of having symptomatic disease among COVID-19 patients admitted to Millennium COVID-19 Care Center in Ethiopia. Results: The result of the multivariable binary logistic regression shows that age group (AOR= 1.818, 95% CI= 1.210, 2.731, p-value=0.004 for 30-39 years; AOR= 1.611, 95% CI= 1.016, 2.554, p-value=0.043 for 40-49 years and AOR= 4.076, 95% CI= 2.582, 6.435, p-value=0.0001 for years and above), sex (AOR= 1.672, 95% CI= 1.216, 2.299, p-value=0.002) and history of diabetes mellitus (AOR= 2.406, 95% CI= 1.384, 4.181, p-value=0.002) were found to be significant factors that determine the development of symptomatic disease in COVID-19 patients.
    keywords: covid-19; disease; license; patients; preprint; symptomatic; symptoms
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        item: #3546 of 7819
          id: cord-297552-n4uvsi3v
      author: Zou, Li
       title: Clinical Characteristics and Risk Factors for Disease Severity and Death in Patients With Coronavirus Disease 2019 in Wuhan, China
        date: 2020-08-13
       words: 3440
      flesch: 49
     summary: Especially, the incidence of hypertension, cardiovascular and cerebrovascular diseases, and chronic pulmonary diseases in severe cases were significantly higher than that in non-severe cases (all P < 0.05). The differences in laboratory findings between non-severe cases and severe cases, as well as survivors and non-survivors Table 3 .
    keywords: cases; covid-19; disease; non; patients; study
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        item: #3547 of 7819
          id: cord-297565-m6wnj83d
      author: Seese, Laura
       title: Programmatic Responses to the Coronavirus Pandemic: A Survey of 502 Cardiac Surgeons
        date: 2020-04-28
       words: 698
      flesch: 39
     summary: As these systems-based changes were evolving, guidelines with adequate specificity to address the complexity of decision-making for delaying cardiac surgery were unavailable. However, at the majority of centers, no patients confirmed to be COVID-19 positive had undergone cardiac surgery (81.7%, n=410).
    keywords: covid-19; patients; surgery
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        item: #3548 of 7819
          id: cord-297599-y4lu8m4k
      author: Luo, Hua
       title: Anti-COVID-19 drug screening: Frontier concepts and core technologies
        date: 2020-10-28
       words: 7681
      flesch: 39
     summary: Res Square Study on pneumonia prescription of traditional chinese medicine to prevent novel coronavirus coronavirus infection in different regions based on data mining Study on the medication regularity of traditional chinese medicine in the prevention and treatment of COVID-19 based on data minin Structure of SARS coronavirus spike receptor-binding domain complexed with receptor Rapid establishment of traditional Chinese medicine prevention and treatment of 2019-nCoV based on clinical experience and molecular docking Study on screening potential traditional Chinese medicines against 2019-nCoV based on Mpro and PLP Screening of Active Ingredients from Traditional Chinese Medicine Against the Novel Coronavirus Based on Molecular Docking Prediction of active components and potential targets of Weixuening mixture for the treatment of novel coronavirus pneumonia based on network pharmacology Study on active compounds of Yupingfeng San in preventing and treating COVID-19 based on network pharmacology and molecular docking technology Exploring active compounds of Jinhua Qinggan Granules for prevention of COVID-19 based on network pharmacology and molecular docking Research advances in application of biochip in traditional Chinese medicine Identifying potential treatments of COVID-19 from Traditional Chinese Medicine (TCM) by using a data-driven approach Study on the mechanisms of active compounds in traditional chinese medicine for the treatment of influenza virus by virtual screening Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations We would like to acknowledge and thank Prof. Mouse plays an important role in researches on the pathogenesis of respiratory diseases associated with human virus infection [45] [46]
    keywords: chinese; coronavirus; cov-2; covid-19; disease; drugs; human; infection; influenza; medicine; model; potential; protein; sars; screening; study; tcm; treatment; virus
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        item: #3549 of 7819
          id: cord-297635-higq7wje
      author: Bahn, Kate
       title: A Feminist Perspective on COVID‐19 and the Value of Care Work Globally
        date: 2020-05-07
       words: 2142
      flesch: 44
     summary: The perceived low value of care work paid and unpaid -and women's disproportionate responsibility in performing this work is an issue that has garnered long-term attention in the field of feminist economics, with valuable lessons for understanding how women are impacted by COVID-19 and mitigating hardships as countries navigate the related economic fallout (Power, 2004) . Sen and social justice Social Provisioning as a Starting Point for Feminist Economics Gender, Time and Inequality: Trends in Women's and Men's Paid Work, Unpaid Work and Free Time Development as freedom Just Checking It Out: Exploring the Significance of Informal Gender Divisions Amongst American Supermarket Employees Marxism and the oppression of women: Toward a unitary theory
    keywords: care; covid-19; crisis; health; women; work
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        item: #3550 of 7819
          id: cord-297638-ab70s980
      author: Stephens, Angela J.
       title: General Guidelines in the Management of an Obstetrical Patient on the Labor and Delivery Unit during the COVID-19 Pandemic
        date: 2020-04-28
       words: 4538
      flesch: 36
     summary: However, there remains no evidence that NSAIDs worsen disease outcomes in COVID-19 patients. For these individuals, the risk/benefit ratio for ACS would suggest the benefits do not seem to outweigh the risks of facilitating or worsening COVID-19 infection.
    keywords: covid-19; delivery; health; infection; labor; patients; respiratory; trial; weeks; women
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        item: #3551 of 7819
          id: cord-297661-62s3bdeu
      author: Mahajan, Ruchi
       title: Eculizumab treatment for renal failure in a pediatric patient with COVID-19
        date: 2020-09-26
       words: 1899
      flesch: 41
     summary: The etiology of AKI in COVID-19 patients has not been fully elucidated, and likely goes beyond the common AKI causes often seen in critically ill patients such as nephrotoxic exposures, hemodynamic instability, and decreased renal perfusion. Complement-mediated TMA should be considered as an etiology for AKI in COVID-19 patients.
    keywords: aki; complement; covid-19; eculizumab; patients
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        item: #3552 of 7819
          id: cord-297673-rh8o4eu9
      author: Vahedian-Azimi, Amir
       title: Comparison of the severity of psychological distress among four groups of an Iranian population regarding COVID-19 pandemic
        date: 2020-08-08
       words: 4144
      flesch: 43
     summary: We hope our study findings will provide data support for the target intervention on psychological health in Iran and different parts of the world during the pandemic. Mental health and psychosocial considerations during the COVID-19 outbreak Factors associated with the psychological impact of severe acute respiratory syndrome on nurses and other hospital workers in Toronto Impact on health care workers employed in high-risk areas during the Toronto SARS outbreak Survey of stress reactions among health care workers involved with the SARS outbreak Severe acute respiratory syndrome (SARS) in Hong Kong in 2003: stress and psychological impact among frontline healthcare workers The psychological impact of severe acute respiratory syndrome outbreak on healthcare workers in emergency departments and how they cope Concerns and preparedness for an avian influenza pandemic: a comparison between community hospital and tertiary hospital healthcare workers Oneyear outcomes and health care utilization in survivors of severe acute respiratory syndrome Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a casecontrolled study Stress and psychological distress among SARS survivors 1 year after the outbreak Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected: interim guidance Long-term stability of depression, anxiety, and stress syndromes Depression anxiety and stress scales (DASS-21): psychometric analysis across four racial groups The depression, anxiety and stress scale (DASS-21) as a screener for depression in substance use disorder inpatients: a pilot study Validation of the depression anxiety stress scales (DASS) 21 as a screening instrument for depression and anxiety in a rural community-based cohort of northern Vietnamese women Validation of depression anxiety and stress scale (DASS-21) for an Iranian population Effect of music on anxiety, stress, and depression levels in patients undergoing coronary angiography Immediate and sustained psychological impact of an emerging infectious disease outbreak on health care workers The forgotten plague: psychiatric manifestations of Ebola, Zika, and emerging infectious diseases Psychobehavioural responses to the 2014 Middle East respiratory syndrome-novel corona virus (MERS CoV) among adults in two shopping malls in Jeddah, western Saudi Arabia Psychological impact of the 2015 MERS outbreak on hospital workers and quarantined hemodialysis patients Management of corona virus disease-19 (COVID-19): the Zhejiang experience.
    keywords: anxiety; covid-19; depression; health; medical; patients; population; stress; study
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        item: #3553 of 7819
          id: cord-297681-m0cckidw
      author: Na, Joo-Young
       title: [Secondary Publication] Standard Operating Procedure for Post-mortem Inspection in a Focus on Coronavirus Disease-19: the Korean Society for Legal Medicine
        date: 2020-08-13
       words: 2816
      flesch: 40
     summary: Furthermore, doctors who perform post-mortem inspections interview the family or the persons who closely contacted the deceased, so the risk of infection surely exists during post-mortem inspection. Post-mortem inspection is an external examination of a dead person and is performed to determine the cause and manner of death.
    keywords: cov-2; covid-19; death; inspection; mortem; sars
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        item: #3554 of 7819
          id: cord-297693-lqyc49t6
      author: Samec, Matthew J
       title: 80-year-old man with dyspnoea and bilateral groundglass infiltrates: an elusive case of COVID-19
        date: 2020-05-27
       words: 2829
      flesch: 41
     summary: The primary symptoms in patients hospitalised with COVID-19 infection are fever (88.7%), cough (67.8%), fatigue (38.1%), dyspnoea (18.7%), myalgia (14.9%) and chills (11.5%). There have been three published case reports of initially negative COVID-19 PCR tests in patients subsequently new disease determined to have COVID-19 infection.
    keywords: case; chest; coronavirus; cov-2; covid-19; disease; infection; patients; sars
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        item: #3555 of 7819
          id: cord-297702-vxcj25sn
      author: Chen, Yuxin
       title: A comprehensive, longitudinal analysis of humoral responses specific to four recombinant antigens of SARS-CoV-2 in severe and non-severe COVID-19 patients
        date: 2020-09-10
       words: 5267
      flesch: 39
     summary: S1-specific and ECD-specific IgA responses were strongly correlated with the neutralization activities in non-severe patients, but not in severe patients. We recently reported that differential longitudinal patterns of nucleic acid and serology testing among severe patients, non-severe patients, and asymptomatic carriers of SARS-CoV-2 [3] .
    keywords: antibody; covid-19; igg; patients; protein; rbd; responses; sars; specific
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        item: #3556 of 7819
          id: cord-297718-y58f2bp0
      author: Mungmungpuntipantip, Rujittika
       title: Ocular manifestation, eye protection, and COVID-19
        date: 2020-03-30
       words: 402
      flesch: 36
     summary: key: cord-297718-y58f2bp0 authors: Mungmungpuntipantip, Rujittika; Wiwanitkit, Viroj title: Ocular manifestation, eye protection, and COVID-19 date: 2020-03-30 journal: In fact, Li et al. pointed out the possibility of ocular manifestation in COVID-19 and the importance of eyewear [2] .
    keywords: infection; manifestation
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        item: #3557 of 7819
          id: cord-297757-3pvstiz6
      author: Sominsky, Luba
       title: One size does not fit all – Patterns of vulnerability and resilience in the COVID-19 pandemic and why heterogeneity of disease matters
        date: 2020-03-20
       words: 2000
      flesch: 34
     summary: As mentioned above, the elderly and those suffering from chronic medical conditions are also at high risk of severe disease outcomes, and, as such, the unique characteristics of these populations should always be considered when attempting to extrapolate scientific discoveries and their therapeutic applications. It appears that COVID-19 infections in children have occurred during the early stages of the pandemic , but they are reported with less frequency and children do not become as sick.
    keywords: children; covid-19; disease
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        item: #3558 of 7819
          id: cord-297759-arg71du6
      author: Triantafyllou, Tania
       title: Esophageal cancer: challenges, concerns, and recommendations for management amidst the COVID-19 pandemic
        date: 2020-06-22
       words: 3745
      flesch: 24
     summary: Cancer patients, and more precisely, immunocompromised patients, may be susceptible to severe illness with potentially fatal consequences [6] . However, existing data on the association between cancer and COVID-19 remain insufficient because of the small numbers of cancer patients that have been investigated, mainly in Eastern countries.
    keywords: cancer; covid-19; esophageal; pandemic; patients; risk; surgery; therapy; treatment
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        item: #3559 of 7819
          id: cord-297777-lnr4w3ek
      author: Rothman, S
       title: The mental health impact of the COVID-19 epidemic on immigrants and racial and ethnic minorities
        date: 2020-06-17
       words: 2908
      flesch: 45
     summary: This can exacerbate feelings in many mental health populations including anxiety, depression, PTSD. Many patients here suffer from underlying mental health issues with comorbid substance abuse.
    keywords: care; covid-19; disease; health; patients; population; risk
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        item: #3560 of 7819
          id: cord-297825-gfyj52of
      author: de Joode, K.
       title: Dutch oncology COVID-19 Consortium (DOCC): Outcome of COVID-19 in patients with cancer in a nationwide cohort study
        date: 2020-09-30
       words: 1137
      flesch: 42
     summary: The organization of cancer centers (CC) has been transformed to minimize virus exposure in cancer patients (pts). All other authors have declared no conflicts of interest LBA80 Outcome and prognostic factors of SARS CoV-2 infection in cancer patients: A cross-sectional study SAKK -Swiss Group for Clinical Cancer Research, SAKK -Swiss Group for Clinical Cancer Research There is ongoing controversy regarding the outcome of COVID-19 in The main objective of the study is to assess the outcome of COVID-19 infection in patients with solid and hematological malignancies, while the main secondary objective is to define prognostic factors of COVID-19 outcome Anticancer treatment within 3 months prior to the diagnosis of COVID-19 included chemotherapy in 65 patients (18%), targeted therapy in 54 patients (15%), steroids in 39 (11%), checkpoint inhibitors in 22 (6%) or no anticancer treatment in 155 patients (43%).
    keywords: cancer; care; covid-19; patients; treatment
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        item: #3561 of 7819
          id: cord-297870-m7n43k4p
      author: Azevedo, Rafael Bellotti
       title: Covid-19 and the cardiovascular system: a comprehensive review
        date: 2020-07-27
       words: 5113
      flesch: 27
     summary: Hence, the presence of heart disease is an important risk factor regarding the prognosis of COVID-19 patients evolving with acute myocardial injury The pathophysiology regarding myocardial damage caused by COVID-19 infection is not completely elucidated.
    keywords: ace2; cardiac; cov-2; covid-19; disease; hypertension; infection; injury; patients; risk; sars
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        item: #3562 of 7819
          id: cord-297878-c4cq92x8
      author: Ali, Mohammed
       title: ST-Elevation Myocardial Infarction in a 27-Year-Old Male With COVID-19
        date: 2020-09-11
       words: 2104
      flesch: 48
     summary: Di Napoli R: Features, Evaluation and Treatment Coronavirus (COVID-19) Guide to understanding the 2019 novel coronavirus What we know so far: COVID-19 current clinical knowledge and research Situation report-22 Catheterization laboratory considerations during the coronavirus (COVID-19) pandemic: from the ACC's Interventional Council and SCAI Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China Cardiovascular considerations for patients, health care workers, and health systems during the COVID-19 pandemic A review of acute myocardial injury in coronavirus disease 2019 Emerging coronaviruses: genome structure, replication, and pathogenesis Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. COVID-19 patients with cardiovascular manifestations are at risk for increased severity of illness.
    keywords: coronavirus; covid-19; disease; injury; patients; sars
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        item: #3563 of 7819
          id: cord-297884-a6yrtuwf
      author: Burke, R. M.
       title: Enhanced Contact Investigations for Nine Early Travel-Related Cases of SARS-CoV-2 in the United States
        date: 2020-05-03
       words: 7351
      flesch: 42
     summary: The results of these investigations suggest that the risk of secondary COVID-19 infection is high among close household contacts of confirmed COVID-19 patients, especially significant others. Rapid detection and isolation of the travel-associated case patients, enabled by public awareness of COVID-19 among travelers from China, may have mitigated transmission risk among close contacts of these cases.
    keywords: case; case patient; contacts; covid-19; exposure; household; license; patient; preprint; travel
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        item: #3564 of 7819
          id: cord-297886-kxb17zx4
      author: Kluger, Dan M.
       title: Impact of healthcare worker shift scheduling on workforce preservation during the COVID-19 pandemic
        date: 2020-07-20
       words: 1727
      flesch: 43
     summary: Figure 2 depicts the outcomes of the 5 staff scheduling scenarios for mean patient hospital stays of 2 and 5 days, typical for maternity and medicine floors, respectively, indicating team failure probability as a function of physician rotation length. However, in all simulations analyzed, physician and nurse rotation lengths of 1-3 days led to higher team failure rates; shorter rotations resulted in exposure of more HCWs to an infected patient.
    keywords: covid-19; days; nurses; patient; team
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        item: #3565 of 7819
          id: cord-297918-840thddt
      author: Yilmaz, Umut
       title: COVID-19: neurologische Manifestationen: Was wir bisher wissen
        date: 2020-09-02
       words: 1349
      flesch: 40
     summary: Die Fälle wiesen die MR-tomographisch typischen zerebralen oder spinalen Herde auf und wurden mit Steroiden, Immunglobulinen oder einer Kombination aus beidem behandelt. Insgesamt wurden in der Metaanalyse von Elul et al. 8
    keywords: bei; cov-2; covid-19; der; des; die; eine; fälle; mit; patienten; sars; und; von
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        item: #3566 of 7819
          id: cord-297965-3bdv6ady
      author: Lee, Sun Young
       title: Operation and Management of Seoul Metropolitan City Community Treatment Center for Mild Condition COVID-19 Patients
        date: 2020-10-12
       words: 4148
      flesch: 49
     summary: The admission and discharge route of CTC patients were investigated. Total 13.6% of CTC patients were admitted to the CTC directly.
    keywords: covid-19; ctc; disaster; disease; hospital; medical; patients; seoul
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        item: #3567 of 7819
          id: cord-298006-4g4eh5un
      author: Giones, Ferran
       title: Revising entrepreneurial action in response to exogenous shocks: Considering the COVID-19 pandemic
        date: 2020-11-30
       words: 4881
      flesch: 32
     summary: Overall, based on theory and research regarding how business planning activities, frugality and emotional support can guide Startup Autobahn, other entrepreneurship stakeholders, and entrepreneurs more broadly, we recommend (1) adjusting to less formal, more frequent, and nuanced business planning activities; (2) adopting a frugal organizational culture that protects and prioritizes resources that directly contribute to the products and services and the long-term vision of the venture; (3) formalizing the informal so that emotional support can be exchanged internally and externally. Besides adjusting the planning processes and exploring frugality as an advantageous behavior in this turbulent environment, we next explore how social support can be a conduit for much-needed personal and professional connection as the crisis continues.
    keywords: business; covid-19; crisis; entrepreneurs; et al; frugality; planning; social; support
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        item: #3568 of 7819
          id: cord-298012-yfzosrok
      author: Harrison, Stephanie L.
       title: Comorbidities associated with mortality in 31,461 adults with COVID-19 in the United States: A federated electronic medical record analysis
        date: 2020-09-10
       words: 3485
      flesch: 42
     summary: Underlying comorbidities including preexisting concurrent cardiovascular or cerebrovascular diseases, hypertension, and diabetes mellitus have been reported as highly prevalent in studies of COVID-19 patients and/or associated with poorer outcomes for these patients [5, 7, 11] . Patients were included if they had 1 or more of the following International Classification of Diseases, Ninth Revision and Tenth Revision, Clinical Modification (ICD-10-CM) codes in their EMRs: U07.1 COVID-19; B97.29 Other coronavirus as the cause of diseases classified elsewhere; B34.2 Coronavirus infection, unspecified; or a positive test result identified with COVID-19-specific laboratory Logical Observation Identifiers Names and Codes (LOINCs).
    keywords: age; covid-19; disease; mortality; patients; study
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        item: #3569 of 7819
          id: cord-298056-svwtfshi
      author: Fabio, Ciceri
       title: Early predictors of clinical outcomes of COVID-19 outbreak in Milan, Italy
        date: 2020-06-12
       words: 3321
      flesch: 37
     summary: We identified J o u r n a l P r e -p r o o f Director-General's opening remarks at the media briefing on COVID-19 The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study Novel Coronavirus(2019-nCoV) Situation Report -11 Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Clinical Characteristics of Coronavirus Disease 2019 in China Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Body composition phenotypes in pathways to obesity and the metabolic syndrome ARDS in Obese Patients: Specificities and Management Acute respiratory distress syndrome Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region Clinical and virological data of the first cases of COVID-19 in Europe: a case series Fast reshaping of intensive care unit facilities in a large metropolitan hospital in Milan, Italy: facing the COVID-19 pandemic emergency Fleischner Society: glossary of terms for thoracic imaging Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the The Novel Coronavirus Disease (COVID-19) Threat for Patients with Cardiovascular Disease and Cancer Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Functional exhaustion of antiviral lymphocytes in COVID-19 patients Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review The First Case of COVID-19 Treated With the Complement C3 Inhibitor AMY-101 The authors thank the entire staff of the San Raffaele Scientific Institute, working every day to ensure the best quality of care to patients and their families. In a large cohort of COVID-19 patients of European origin, main risk factors for mortality were older age, comorbidities, low lymphocyte count and high RALE.
    keywords: china; covid-19; data; disease; hospital; mortality; patients; risk; score
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        item: #3570 of 7819
          id: cord-298079-hgdyxk98
      author: Hsu, Jeffrey J.
       title: Heart Transplantation in the Early Phase of the COVID‐19 Pandemic: A Single‐Center Case Series
        date: 2020-07-12
       words: 2099
      flesch: 48
     summary: 12, 13 However, a recent study found a 25% case fatality rate among OHT patients, 14 and a full understanding of COVID-19 in this population remains to be determined. The impact of social distancing and hand hygiene education that post-transplant patients receive likely played a strong role.
    keywords: cov-2; covid-19; heart; patients; sars; transplantation
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        item: #3571 of 7819
          id: cord-298090-9b3d33ih
      author: Charlier, P
       title: L’hydroxy-chloroquine pour traiter les patients infectés du COVID-19: quelques leçons d'an-thropologie médicale et d'histoire de la médecine
        date: 2020-08-27
       words: 1828
      flesch: 46
     summary: Here, the authors question the implementation of hydroxychloroquine treatment in the context of the Covid-19 pandemic. Here, the authors question the implementation of hydroxychloroquine treatment in the context of the Covid-19 pandemic.
    keywords: chloroquine; covid-19; pandemic; treatment
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        item: #3572 of 7819
          id: cord-298094-ctikhqvr
      author: Elias, Pierre
       title: The Prognostic Value of Electrocardiogram at Presentation to Emergency Department in Patients With COVID-19
        date: 2020-08-15
       words: 4172
      flesch: 47
     summary: 6 Electrocardiographic (ECG) abnormalities have been described but there have been no large studies of ECG abnormalities in COVID-19 patients nor their correlation with clinical outcomes. We propose that in the setting of triaging COVID-19 patients in the ED, ECG be treated as a sixth vital sign.
    keywords: abnormalities; covid-19; disease; ecg; patients; presentation
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        item: #3573 of 7819
          id: cord-298127-zp8kze6t
      author: Shao, Fei
       title: Cardiopulmonary resuscitation of inpatients with severe COVID-19 pneumonia: the Wuhan experience
        date: 2020-05-11
       words: 411
      flesch: 37
     summary: All ICU patients and half of ward patients had ECG monitoring at the time of cardiac arrest. Here we report our personal experience of prevention, treatment and staff safety for IHCA patients with severe COVID-19 pneumonia.
    keywords: covid-19; patients
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        item: #3574 of 7819
          id: cord-298156-d0pb1kik
      author: Cheval, Sorin
       title: Observed and Potential Impacts of the COVID-19 Pandemic on the Environment
        date: 2020-06-10
       words: 11035
      flesch: 42
     summary: Supplementary Materials: The following are available online at http://www.mdpi.com/1660-4601/17/11/4140/s1, List S1: Calendar of events relevant for COVID-19 impact on environment (31 December 2019-30 April 2020), Figure S1 : The examination of the relationship between climate and Coronavirus focuses on two queries: (a) how the climate can modulate the spread and persistence of the virus, and (b) the extent of the impact of the virus on economic policies taken to offset climate impacts.
    keywords: air; change; climate; coronavirus; covid-19; covid-19 pandemic; crisis; effects; emissions; health; human; impacts; pandemic; reduction; sars; spread; systems; term; water
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        item: #3575 of 7819
          id: cord-298163-220l6xhq
      author: Deng, Chu-Xia
       title: Glucocorticoids save lives in COVID-19 patients
        date: 2020-07-07
       words: 937
      flesch: 42
     summary: Why should the activation of ACE2 benefits COVID-19 patients? Therefore, the repletion of ACE2 might be responsible for the rapidly deterioration to severe or critical conditions of COVID-19 patients.
    keywords: ace2; covid-19; patients
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        item: #3576 of 7819
          id: cord-298185-w37nvorf
      author: Cao, Kai
       title: Current Evidence of 2019 Novel Coronavirus Disease (COVID-19) Ocular Transmission: A Systematic Review and Meta-Analysis
        date: 2020-10-24
       words: 2558
      flesch: 47
     summary: The evidence on the positive rate of conjunctival swab samples and the prevalence rates of ocular symptoms indicated that COVID-19 ocular transmission was possible but less likely. Similarly, our meta-analysis found that up to 10% of COVID-19 patients had ocular symptoms and 3% of conjunctival swab samples were positive in COVID-19 patients, supporting the possibility of transmission through the ocular surface.
    keywords: conjunctival; conjunctivitis; covid-19; rate; studies
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        item: #3577 of 7819
          id: cord-298191-sqfx171j
      author: Ga, Hyuk
       title: The Korean Geriatrics Society COVID-19 Strategy for Older Adults
        date: 2020-06-26
       words: 710
      flesch: 39
     summary: Especially, care assistants should wash their hands and discard gloves every time they change residents in their care Make clear to residents and workers the actions required to protect against COVID-19 infection Suspected COVID-19 patients should be reported to public healthcare centers, isolated from others, and tested for infection Blocking spread BETWEEN facilities Maneuver for COVID-19 Combat for local government (version 7-1) COVID-19 and older people in Asia: AWGS calls to actions An international definition for nursing home Perspective on long term care hospitals in Korea COVID-19: Coronavirus disease (COVID-2019) situation reports World Health Organization; c2020 COVID-19: the case for health-care worker screening to prevent hospital transmission Risk factors and causes of short-term mortality after emergency department discharge in older patients: using nationwide health insurance claims data Prevalence of frailty in nursing homes: a systematic review and meta-analysis Use of the frailty index and FRAIL-NH scale for the assessment of the frailty status of elderly individuals admitted in a long-term care hospital in Korea Mortality associated with COVID-19 outbreaks in care homes: early international evidence International Long Term Care Policy Network Preventive strategies for coronavirus disease (COVID-19) infection in older adults ?
    keywords: care; covid-19; term
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        item: #3578 of 7819
          id: cord-298200-rjlya399
      author: De los Santos, J. A. A.
       title: Impact of COVID-19 on the Psychological Well-Being and Turnover Intentions of Frontline Nurses in the Community: A Cross-Sectional Study in the Philippines
        date: 2020-08-06
       words: 3393
      flesch: 51
     summary: Our results revealed that community nurses are relatively young and have been in government service since the onset of their professional careers. Moreover, our results suggest that despite their job satisfaction, community nurses are not married to their jobs during this pandemic.
    keywords: covid-19; license; medrxiv; nurses; preprint
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        item: #3579 of 7819
          id: cord-298257-uptgv2xv
      author: Cheng, Wenwen
       title: Efficacy and Safety of Corticosteroid Treatment in Patients With COVID-19: A Systematic Review and Meta-Analysis
        date: 2020-09-09
       words: 5809
      flesch: 37
     summary: A series of clinical studies demonstrated that low-dose or physiological-dose corticosteroid treatments in patients with septic shock caused by pulmonary infection significantly shortened the length of ICU hospital stay and reversed the progression of shock (Rhodes et al., 2017; Marik, 2018) . Recently, emerging evidence from the initial clinical trial revealed a clear benefit of dexamethasone in patients with COVID-19 Fadel et al., 2020) .
    keywords: cohort; corticosteroid; covid-19; et al; group; patients; studies; study
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        item: #3580 of 7819
          id: cord-298258-satk2t9z
      author: Kahwash, Basil M.
       title: Allergy/Immunology Trainee Experiences During the COVID-19 Pandemic: AAAAI Work Group Report of the Fellows-in-Training Committee
        date: 2020-11-02
       words: 3555
      flesch: 39
     summary: A 17-item electronic questionnaire was distributed to 380 FIT members of the AAAAI enrolled in US and Canadian allergy and immunology fellowship training programs. This Work Group Report summarizes and presents the data from the survey of FITs in allergy and immunology training programs in the United States and Canada to understand workflow and education changes, as well as concerns among fellows in response to change.
    keywords: allergy; covid-19; fits; immunology; pandemic; study; survey; training
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        item: #3581 of 7819
          id: cord-298281-wkje5jyt
      author: Chan, Vinson Wai-Shun
       title: A systematic review on COVID-19: urological manifestations, viral RNA detection and special considerations in urological conditions
        date: 2020-05-27
       words: 3497
      flesch: 50
     summary: 5.74% (95% CI 2.88–9.44%) of COVID-19 patients had positive viral RNA in urine samples, but the duration of viral shedding in urine was unknown. 65.82% (95% CI 45.71–83.51%) of COVID-19 patients had positive viral RNA in stool samples, which were detected from 2 to 47 days from symptom onset.
    keywords: covid-19; et al; patients; rna; sars; studies
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        item: #3582 of 7819
          id: cord-298287-larzpygd
      author: Bhat, Shubha
       title: Impact of Clinical Pharmacists in Inflammatory Bowel Disease Centers During the COVID-19 Pandemic
        date: 2020-07-20
       words: 833
      flesch: 33
     summary: In a time where COVID-19 has also resulted in staffing changes and even deployment of gastroenterologists to COVID-19 inpatient services, having clinical pharmacists dedicated to these tasks permits for continued delivery of optimal patient care for patients with IBD. Clinical pharmacists embedded in gastroenterology practices permit for continued optimal patient care during a pandemic.
    keywords: covid-19; patients; pharmacist
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        item: #3583 of 7819
          id: cord-298295-epxd03pt
      author: Eckermann, M.
       title: 3d Virtual Patho-Histology of Lung Tissue from Covid-19 Patients based on Phase Contrast X-ray Tomography
        date: 2020-06-23
       words: 6503
      flesch: 47
     summary: For Covid-19 lung tissue, the scans were recorded at the GINIX endstation of the PETRA III storage ring (DESY,Hamburg). Based on the extracted structural parameters, the degree of inflammation and swelling of lung tissue can be evaluated.
    keywords: alveolar; beam; blood; covid-19; fig; license; lung; phase; preprint; sample; size; tissue; tomography
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        item: #3584 of 7819
          id: cord-298301-p1zj6jg9
      author: Dey, Lopamudra
       title: Machine Learning Techniques for Sequence-based Prediction of Viral-Host Interactions between SARS-CoV-2 and Human Proteins
        date: 2020-09-03
       words: 6310
      flesch: 46
     summary: Choosing negative examples for the prediction of protein-protein interactions Prediction of interactions between viral and host proteins using supervised machine learning methods Sequence-based prediction of protein protein interaction using a deep-learning algorithm Human protein reference database-2009 update A human functional protein interaction network and its application to cancer data analysis Supervised classification algorithms in machine learning: A survey and review. We found a large number of predicted human proteins interact with more than one virus.
    keywords: amino; classifier; coronavirus; covid-19; dataset; features; human; interactions; learning; machine; prediction; proteins; sars; virus
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        item: #3585 of 7819
          id: cord-298311-5vlycjbj
      author: Hur, Jian
       title: Usefulness of an Online Preliminary Questionnaire under the COVID-19 Pandemic
        date: 2020-05-19
       words: 798
      flesch: 42
     summary: Since patients with underlying diseases frequently visit hospitals for treatments, and hospitals are a place of mass congregation, special measures are needed to prevent hospital-acquired secondary infection of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We believe that the use of our mobile self-report questionnaire by other hospitals could be helpful in overcoming the COVID-19 pandemic.
    keywords: covid-19; hospital
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        item: #3586 of 7819
          id: cord-298325-2gm4fnqi
      author: Shah, Sonia
       title: Novel use of home pulse oximetry monitoring in COVID‐19 patients discharged from the emergency department identifies need for hospitalization
        date: 2020-06-17
       words: 4002
      flesch: 47
     summary: All rights reserved Accepted Article Global Surveillance for human infection with coronavirus disease (COVID-19) Clinical progression of patients with COVID-19 in Shanghai A multicentre prospective observational study comparing arterial blood gas values to those obtained by pulse oximeters used in adult patients attending Australian and New Zealand hospitals Acute respiratory failure Relating oxygen partial pressure, saturation and content: the haemoglobin-oxygen dissociation curve Oxygen saturations less than 92% are associated with major adverse events in outpatients with pneumonia: a population-based cohort study Critical care crisis and some recommendations during the COVID-19 epidemic in China Pathological findings of COVID-19 associated with acute respiratory distress syndrome COVID-19 pneumonia: different respiratory treatments for different phenotypes? Evaluation and Treatment Coronavirus (COVID-19) Cytokine Storm in COVID-19 and Treatment Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan novel coronavirus (2019-nCoV) outbreak: A new challenge Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Rational use of personal protective equipment for coronavirus disease (COVID-19) and considerations during severe shortages Pulse oximetry: understanding its basic principles facilitates appreciation of its limitations Evaluating the accuracy of commercially available finger pulse oximeters in a hospital setting Risk factors for disease progression in hospitalized patients with COVID-19: a retrospective cohort study The importance of hypertension as a risk factor for severe illness and mortality in COVID-19 Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 2019 -United States Risk factors for disease severity, unimprovement, and mortality in COVID-19 patients in Wuhan, China False-negative of RT-PCR and prolonged nucleic acid However, there are currently no data to guide the use of home pulse oximetry in COVID-19 patients or its validity in identifying disease progression.
    keywords: covid-19; home; patients; pulse; spo; study
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        item: #3587 of 7819
          id: cord-298327-j04nyg5y
      author: Lv, Zhihua
       title: Clinical characteristics and co-infections of 354 hospitalized patients with COVID-19 in Wuhan, China: a retrospective cohort study
        date: 2020-05-18
       words: 1897
      flesch: 44
     summary: Although previous studies have demonstrated certain clinical characteristics of patients 34 with COVID-19 [8, 11, 12] , their detail clinical characteristics are still limited and the sex 35 differences in clinical characteristics of COVID-19 patients have not been well studied. Preliminary analysis indicated that higher white blood cell and 129 neutrophil counts, as well as higher levels of D-dimer, IL-6, IL-10, CRP and PCT were found 130 in male patients compared to those of females, which was similar to patients in critical and 131 severe groups compared with those of mild groups (Table 2) .
    keywords: cases; covid-19; patients; sars
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        item: #3588 of 7819
          id: cord-298343-nvuc1j7t
      author: Ma, J.
       title: Exhaled breath is a significant source of SARS-CoV-2 emission
        date: 2020-06-02
       words: 2794
      flesch: 56
     summary: Surface swab samples 35 from a pillow case (20YJ3372) and hands (20YJ3378) of patient TH-YZ1 were shown to contain SARS-CoV-2, but no virus was detected in this patient's EBC sample (Fig. 2B) . Upon the collection, surface swab samples were immediately deposited into a 3 mL virus collection liquid (Yocon Biology, Inc), and further delivered to the laboratory for SARS-CoV-2 analysis on the same day.
    keywords: air; cov-2; covid-19; fig; patients; samples; sars; surface
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        item: #3589 of 7819
          id: cord-298372-4pw1y404
      author: Koch, Lionel
       title: Natural outbreaks and bioterrorism: How to deal with the two sides of the same coin?
        date: 2020-08-18
       words: 6210
      flesch: 34
     summary: Over the past ten years, epidemiological and mathematical modelling data were essential for risk characterisation and management during infectious disease outbreaks [92] but ironically, the rising power of AI systems will not erase the role of human experts [93] . The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study To what extent does evidence support decision making during infectious disease outbreaks?
    keywords: attack; covid-19; crisis; data; detection; disease; health; management; outbreak; pandemic; response; risk; sars; system; virus
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        item: #3590 of 7819
          id: cord-298426-hhly45md
      author: Zhang, Shan-Yan
       title: Clinical characteristics of different subtypes and risk factors for the severity of illness in patients with COVID-19 in Zhejiang, China
        date: 2020-07-08
       words: 3728
      flesch: 48
     summary: Several studies demonstrated that differences in COVID-19 disease prevalence and severity were associated with sex, which was similar to our results Although hemoptysis was an atypical symptom, it was reported that there was COVID-19 patient admitted only with hemoptysis as the initial symptom [18] .
    keywords: cases; clinical; covid-19; illness; patients; sars; severity; study; type
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        item: #3591 of 7819
          id: cord-298440-0pb8ssj2
      author: Rascón-Ramírez, Fernando J
       title: Supra and infratentorial massive strokes in previously healthy young patients with SARS-CoV-2. The role of neurosurgery
        date: 2020-09-06
       words: 1430
      flesch: 45
     summary: COVID-19 patients can develop large-scale ischemic strokes in previously healthy patients without risk factors, especially in patients who develop an acute respiratory distress syndrome (SARS-CoV-2). COVID-19 patients can develop large-scale ischemic strokes in previously healthy patients without risk factors, especially in patients who develop an acute respiratory distress syndrome (SARS-CoV-2).
    keywords: covid-19; patients; sars; stroke; vertebral
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        item: #3592 of 7819
          id: cord-298461-tyhtdawb
      author: Zhao, L.
       title: COVID-19: Effects of weather conditions on the propagation of respiratory droplets
        date: 2020-05-25
       words: 7836
      flesch: 48
     summary: The transmitting pathway of COVID-19 through respiratory droplets is divided into short-range droplet contacts and long-range aerosol exposure. The transmitting pathway of COVID-19 through respiratory droplets is divided into short-range droplet contacts and long-range aerosol exposure.
    keywords: aerosol; air; conditions; droplet; figure; medrxiv; particles; preprint; transmission; weather
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        item: #3593 of 7819
          id: cord-298475-3bhiattk
      author: Farmaki, Anna
       title: Impacts of Covid-19 on peer-to-peer accommodation platforms: Host perceptions and responses
        date: 2020-09-03
       words: 9840
      flesch: 40
     summary: Drawing from semi-structured interviews with P2P accommodation hosts, this study aims to explore: a) their perceptions of the short-term impacts of the pandemic on their hosting practice, b) their responses to the pandemic and c) their perceptions of the long-term impacts of the pandemic on the P2P accommodation sector. Concerns from P2P accommodation hosts have also been voiced as many struggled financially during the pandemic due to the loss of reservations (Johnson and Davis, 2020) .
    keywords: accommodation; airbnb; covid-19; et al; hospitality; hosting; hosts; impacts; p2p; p2p accommodation; pandemic; participants; platforms; sector; study; term; tourism
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        item: #3594 of 7819
          id: cord-298505-r7ihqb96
      author: Górski, Andrzej
       title: Sepsis, Phages, and COVID-19
        date: 2020-10-15
       words: 3741
      flesch: 41
     summary: Thus, clinical trials assessing the value of phage therapy in sepsis, including viral sepsis, are urgently needed. In this review, we summarize the progress in treating sepsis with phage therapy over the last three years.
    keywords: blood; cells; covid-19; human; patients; phage; sepsis; therapy; treatment
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        item: #3595 of 7819
          id: cord-298536-kksivbh8
      author: Lahav, Yael
       title: Psychological Distress Related to COVID-19 – The Contribution of Continuous Traumatic Stress
        date: 2020-08-10
       words: 6723
      flesch: 36
     summary: Trauma exposure, COVID-19-related stressors, and psychological distress related to COVID-19 (anxiety, depression, and peritraumatic stress symptoms) were assessed. Individuals who had been exposed to trauma, and to CTS in particular, had elevated anxiety, depression, and peritraumatic stress symptoms compared to individuals without such a history or to survivors of non-ongoing traumatic events.
    keywords: anxiety; covid-19; depression; distress; exposure; participants; stress; stress symptoms; symptoms; trauma
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        item: #3596 of 7819
          id: cord-298557-85e0l8or
      author: Bellido, Virginia
       title: CONSECUENCIAS DE LA COVID-19 SOBRE LAS PERSONAS CON DIABETES
        date: 2020-05-11
       words: 1277
      flesch: 26
     summary: Teniendo en cuenta que el éxito de un protocolo de manejo clínico depende en gran medida de la capacitación del personal responsable de su aplicación, y que la magnitud de la situación condiciona que muchos de los profesionales sanitarios que están en primera línea de atención tengan menos experiencia, la participación del endocrinólogo y de la enfermera especialista en diabetes en la adaptación de los protocolos y la atención de los pacientes hospitalizados con hiperglucemia contribuirá, sin duda, a la mejor atención de los pacientes con diabetes y COVID-19. La existencia de base en la diabetes de un estado de inflamación crónica, el deterioro de la respuesta inmunológica y la alteración de la coagulación, podrían estar entre los mecanismos fisiopatológicos subyacentes que contribuyen al aumento de la morbimortalidad de la COVID-19 en las personas con diabetes.
    keywords: con; covid-19; del; diabetes; los; pacientes; que
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        item: #3597 of 7819
          id: cord-298600-cnolne6k
      author: Majeed, Talal
       title: The Role of the Computed Tomography (CT) Thorax in the Diagnosis of COVID-19 for Patients Presenting with Acute Surgical Emergencies. A Single Institute Experience
        date: 2020-10-20
       words: 3223
      flesch: 43
     summary: Standard reporting for COVID-19 infection for CT chest based on guidelines from British Society of Thoracic Imaging (BSTI) and Radiological Society of North America (RSNA) was used. Our aim was to determine the diagnostic accuracy in terms of sensitivity and specificity of CT chest in diagnosing and confirming COVID-19 infection in patients presenting with acute surgical and medical pathologies.
    keywords: covid-19; diagnosis; infection; patients; pcr; test
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        item: #3598 of 7819
          id: cord-298639-v9yg80jw
      author: Chen, Yuxin
       title: High SARS-CoV-2 Antibody Prevalence among Healthcare Workers Exposed to COVID-19 Patients
        date: 2020-06-04
       words: 3378
      flesch: 43
     summary: key: cord-298639-v9yg80jw authors: Chen, Yuxin; Tong, Xin; Wang, Jian; Huang, Weijin; Yin, Shengxia; Huang, Rui; Yang, Hailong; Chen, Yong; Huang, Aijun; Liu, Yong; Chen, Yan; Yuan, Ling; Yan, Xiaomin; Shen, Han; Wu, Chao title: High SARS-CoV-2 Antibody Prevalence among Healthcare Workers Exposed to COVID-19 Patients date: 2020-06-04 journal: J Infect DOI: 10.1016/j.jinf.2020.05.067 sha: doc_id: 298639 cord_uid: v9yg80jw Risk analysis revealed that wearing face mask could reduce the infection risk (odds ratio [OR], 0.127, 95% confidence interval [CI] 0.017, 0.968), while when exposed to COVID-19 patients, doctors might have higher risk of seroconversion (OR, 346.837, 95% CI 8.924, 13479.434), compared with HCWs exposed to colleagues as well as nurses and general service assistants who exposed to patients.
    keywords: cov-2; covid-19; hcws; infection; mask; patients; samples; sars
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        item: #3599 of 7819
          id: cord-298640-zwg8ueyb
      author: Smereka, Jacek
       title: The use of personal protective equipment in the COVID-19 pandemic era
        date: 2020-04-15
       words: 802
      flesch: 36
     summary: Medical personnel protection is of particular importance because of the risk of infecting other members of medical teams, including not only physicians, nurses or paramedics, but also other support personnel necessary to maintain the continuity of care for patients [1, 2] . Medical personnel protection is a priority as in their case, infection or even the need for quarantine may pose a real threat to patients.
    keywords: covid-19; personnel
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        item: #3600 of 7819
          id: cord-298654-sb9kevkb
      author: Yang, Xiang-Hong
       title: Focus on coronavirus disease 2019 associated coagulopathy
        date: 2020-09-20
       words: 1880
      flesch: 32
     summary: Similar to severe acute respiratory syndrome (SARS), it has been shown that the elevation of D-dimer is the most prevalent coagulation abnormality in COVID-19 patients, which accounting for 36% to 46.4% of all cases. [4] Different from SARS, the changes in activated partial thromboplastin time (APTT) and prothrombin time (PT) in COVID-19 patients are inconsistent.
    keywords: coagulation; coagulopathy; covid-19; dic; patients
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        item: #3601 of 7819
          id: cord-298663-t4aui90j
      author: Zhang, Qiongshuai
       title: The efficacy and safety of Jinhua Qinggan granule (JHQG) in the treatment of coronavirus disease 2019 (COVID-19): A protocol for systematic review and meta analysis
        date: 2020-06-12
       words: 1612
      flesch: 49
     summary: WHO Coronavirus Disease (COVID-19) Dashboard Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study COVID-19) Outbreak: what the department of radiology should know Digestive symptoms in COVID-19 patients with mild disease severity: clinical presentation, stool viral RNA testing, and outcomes Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review Potential interventions for novel coronavirus in China: a systematic review Epidemiological and clinical features of the 2019 novel coronavirus outbreak in China Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Diagnosis and Treatment of Novel Coronavirus Pneumonia (trial version 3 NHC. During the fight of COVID-19 epidemic in China, it was found that Chinese herbal medicine had a good effect on COVID-19.
    keywords: clinical; coronavirus; covid-19; studies; treatment
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        item: #3602 of 7819
          id: cord-298676-8wm95ghd
      author: Choudhery, Mahmood S
       title: Stem Cell Therapy for Covid‐19: Possibilities and Challenges
        date: 2020-08-07
       words: 2138
      flesch: 37
     summary: Recent use of stem cells for critically ill Covid‐19 patients in a small group of patients in China and subsequent Emergency Use Authorization (EUA) of stem cells by Food and Drug Administration (FDA) to GIOSTAR (Global Institute of Stem Cell Therapy and Research) and Athersys has created excitement among medical community. As a result, several clinical trials have been registered using stem cells for Covid‐19 treatment that aim to use different cell sources, dosage and importantly diverse targeted patient groups.
    keywords: cells; covid-19; mesenchymal; patients; stem; use
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        item: #3603 of 7819
          id: cord-298679-w0yp4u19
      author: Iftimie, Simona
       title: Risk factors associated with mortality in hospitalized patients with SARS-CoV-2 infection. A prospective, longitudinal, unicenter study in Reus, Spain
        date: 2020-09-03
       words: 3589
      flesch: 42
     summary: Wuhan studies report that the incidence of cancer is higher in COVID-19 patients than in the general population [34, 35] . One aspect that caught our attention is that, despite our hospital being the reference center for Oncology in our province, the number of cancer patients infected with COVID-19 was relatively low.
    keywords: coronavirus; cov-2; covid-19; disease; mortality; patients; sars; study
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        item: #3604 of 7819
          id: cord-298682-5heb9biz
      author: Stephen, Shine
       title: COVID-19: Weighing the Endeavors of Nations, with Time to Event Analysis
        date: 2020-08-17
       words: 2889
      flesch: 50
     summary: US nationals returning home after travelling through COVID-19 affected countries had to undergo a compulsory health screening and be quarantined for a fortnight. Two days later, a public health emergency was declared, which barred entry to foreign nationals who had visited COVID-19 affected nations (China, Iran, United Kingdom, Ireland, or the 26 European countries) in the past 2 weeks.
    keywords: coronavirus; covid-19; health; nations; pandemic; public; testing
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        item: #3605 of 7819
          id: cord-298686-cpuw9ev4
      author: Nuno‐Gonzalez, A.
       title: Prevalence of mucocutaneous manifestations, oral and palmoplantar findings in 666 patients with COVID‐19 in a field hospital in Spain
        date: 2020-09-24
       words: 918
      flesch: 41
     summary: First, we only included patients with mild-to-moderate COVID-19 pneumonia and cannot provide data on skin disease in asymptomatic patients or with more severe forms of COVID-19. Burning sensation was reported in 5.3% of patients and taste disturbances (dysgeusia) was commonly associated.
    keywords: covid-19; manifestations; patients; study
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        item: #3606 of 7819
          id: cord-298725-da71febn
      author: Okuhama, Ayako
       title: Detection of SARS-CoV-2 in Hemodialysis Effluent of Patient with COVID-19 Pneumonia, Japan
        date: 2020-11-17
       words: 1438
      flesch: 37
     summary: Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis Clinical features of patients infected with 2019 novel coronavirus in Wuhan COVID-19 in hemodialysis patients: A report of 5 cases Interim guidance for infection prevention and control recommendations for patients with suspected or confirmed COVID-19 in outpatient hemodialysis facilities Development of genetic diagnostic methods for novel coronavirus 2019 (nCoV-2019) in Japan Hemodialysis affects phenotype and proliferation of CD4-positive T lymphocytes Continuous renal replacement therapy for a patient with severe COVID-19 Detection of SARS-CoV-2 in different types of clinical specimens Blood purification for critical illness: cytokines adsorption therapy Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1 US Centers for Disease Control and Prevention. Recommendations for preventing transmission of infections among chronic hemodialysis patients Tokyo 162-8655, Japan; email: ishikanemasahiro@gmail.com
    keywords: cov-2; covid-19; hemodialysis; patient; sars
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        item: #3607 of 7819
          id: cord-298744-paippv15
      author: Biddlestone, Mikey
       title: Cultural orientation, power, belief in conspiracy theories, and intentions to reduce the spread of COVID‐19
        date: 2020-06-27
       words: 3564
      flesch: 32
     summary: Vertical individualism, however, negatively predicted social distancing intentions, directly and indirectly through belief in COVID-19 conspiracy theories, standardized indirect effect = À.04 [À0.06, À0.02], and feelings of powerlessness, standardized indirect effect = À0.02 [À0.04, À0.01]. Finally, as predicted, belief in COVID-19 conspiracy theories negatively predicted social distancing intentions both directly and indirectly through feelings of powerlessness, standardized indirect effect = À.04 [À0.05, À0.01].
    keywords: collectivism; conspiracy; covid-19; feelings; intentions; powerlessness; theories
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        item: #3608 of 7819
          id: cord-298763-u5xn392m
      author: Mutala, Timothy Musila
       title: Radiology practice in sub-Saharan Africa during the COVID-19 outbreak: points to consider
        date: 2020-09-07
       words: 3102
      flesch: 47
     summary: Role of radiology in COVID-19: radiology plays a significant role in management of COVID-19 patients, especially chest CT and chest X-ray Therefore, it is prudent that designated imaging facilities be the ones that handle COVID-19 patients to save on this scarce resource.
    keywords: africa; cases; covid-19; health; imaging; management; patients; radiology
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        item: #3609 of 7819
          id: cord-298774-l4jwlc8p
      author: Li, Haomin
       title: Changes in Children’s Healthcare Visits During COVID-19 Pandemic in Hangzhou, China
        date: 2020-05-19
       words: 946
      flesch: 45
     summary: In this study, we analyzed pediatric visit data during the pandemic in Hangzhou to identify whether restrictions affected children's health. As shown in Figure 2 As shown in Figure 2 , B, there also were conditions for which visits rate increased more than 3-fold during this period.
    keywords: children; covid-19; health
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        item: #3610 of 7819
          id: cord-298777-hit7rs6q
      author: Zhang, Linjie
       title: What we know so far about Coronavirus Disease 2019 in children: A meta‐analysis of 551 laboratory‐confirmed cases
        date: 2020-06-10
       words: 3876
      flesch: 50
     summary: We selected randomized trials, observational studies, case series or case reports, and research letters of children ages birth to 18 years with laboratory‐confirmed COVID‐19. Since the first papers published on 24 January 2020, 2,5,6 there has been a growing number of publications related to However, the number of studies in children is still limited, and most of them were case series or case reports with a small number of patients.
    keywords: case; children; coronavirus; covid-19; patients; series
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        item: #3611 of 7819
          id: cord-298778-wnbqqzot
      author: Hamza, Marwa S.
       title: Cross-Sectional Study on Awareness and Knowledge of COVID-19 Among Senior pharmacy Students
        date: 2020-06-15
       words: 4239
      flesch: 50
     summary: KS ranged from 0 to 12, with the higher scores demonstrating an increased level of pandemic COVID-19 knowledge. In the present study, the main objective was to measure COVID-19 related knowledge of pharmacy senior students.
    keywords: covid-19; disease; health; information; knowledge; questions; students; study
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        item: #3612 of 7819
          id: cord-298817-q29br2o5
      author: Ribera, Aida
       title: El riesgo competitivo puede explicar en gran medida la disminución de los ingresos por enfermedad cardiovascular aguda durante la pandemia de COVID-19. Respuesta
        date: 2020-09-03
       words: 467
      flesch: 31
     summary: Por otro lado, cabe esperar que una reducción tan significativa de la actividad asistencial no dedicada a la COVID-19 5 tenga un impacto importante a medio plazo en la salud y en la organización de la atención al paciente con enfermedad cardiovascular. El exceso de mortalidad por cualquier causa de más del 50% que hubo en Cataluña (11.568 defunciones), especialmente de mayores de 74 años (9.749) 2 , explicaría también el ligero descenso de la media de edad de los pacientes atendidos 3 .
    keywords: covid-19; por
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        item: #3613 of 7819
          id: cord-298846-qb0frju1
      author: Waszkiewicz, Napoleon
       title: Possible special needs for mental online support in female and male health care workers during the COVID‐19
        date: 2020-07-14
       words: 720
      flesch: 39
     summary: However, the proportion of COVID-19 cases in health care workers is still very high (up to 20%). The truism is that medical health workers who are well, best serve their patients.
    keywords: covid-19; health; stress
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        item: #3614 of 7819
          id: cord-298865-5pe33eos
      author: Yang, Tuo-Yun
       title: Clinical characteristics of patients with COVID-19 presenting with gastrointestinal symptoms as initial symptoms: Retrospective case series
        date: 2020-07-26
       words: 2646
      flesch: 43
     summary: COVID-19 patients presenting with gastrointestinal symptoms as initial symptoms need more days of viral shedding and hospitalization than the patients presenting with pulmonary symptoms. According to recent publications [3] , the most common initial symptoms in COVID-19 patients have been recognized as pulmonary symptoms, such as fever, cough, and expectoration.
    keywords: coronavirus; covid-19; group; patients; symptoms
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        item: #3615 of 7819
          id: cord-298866-dzatps7b
      author: Licskai, Christopher
       title: Key highlights from the Canadian Thoracic Society’s Position Statement on the Optimization of Asthma Management during the COVID-19 Pandemic
        date: 2020-05-28
       words: 1546
      flesch: 41
     summary: Most studies to date suggest that asthma patients have no greater risk of acquiring COVID-19 than the general population. In the largest studies published to date with 44,672 patients (China) and 5,700 patients (United States of America) respectively, the prevalence of asthma in the COVID-19 population was below or approximated the expected general population prevalence; asthma patients were not over-represented.
    keywords: asthma; covid-19; fees; patients; work
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        item: #3616 of 7819
          id: cord-298867-hzshnq7b
      author: Raham, T. F.
       title: Impact of Duration of Cessation of Mass BCG Vaccination Programs on Covid -19 Mortality
        date: 2020-08-23
       words: 1973
      flesch: 39
     summary: Looking for duration of cessation of BCG vaccination program as factor is a new idea up to my knowledge to be tested in relation to COVID-19 mortality supporting the hypotheses of effectiveness of BCG vaccinations programs in prevention of COVID-19 mortality. Recommendations: Decisions on BCG vaccination program cessation might be en reconsidered.
    keywords: bcg; preprint; vaccination
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        item: #3617 of 7819
          id: cord-298881-u6uqroi0
      author: Huang, Ian
       title: Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia – A systematic review, meta-analysis, and meta-regression()
        date: 2020-04-17
       words: 3162
      flesch: 43
     summary: The authors declared no conflict of interest Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Diabetes is a risk factor for the progression and prognosis of COVID-19 COVID-19 and diabetes Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected Report of the WHO-China Joint Mission on Coronavirus Disease 2019 ( COVID-19 ) Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Clinical features and outcomes of 221 patients with COVID-19 in Wuhan Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China Clinical Features and Treatment of COVID-19 Patients in Northeast Chongqing Platelet-to-lymphocyte ratio is associated with prognosis in patients with Corona Virus Disease-19 Dysregulation of immune response in patients with COVID-19 in Wuhan, China Clinical Characteristics of Patients with Severe Pneumonia Caused by the 2019 Novel Coronavirus in Wuhan Early Prediction of Disease Progression in 2019 Novel Coronavirus Pneumonia Patients Outside Wuhan with CT and Clinical Characteristics Clinical characteristics of 51 patients discharged from hospital with COVID-19 in Chongqing，China Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients COVID-19 in a Designated Infectious Diseases HospitalOutside Hubei Province Neutrophil-to-Lymphocyte Ratio Predicts Severe Illness Patients with 2019 Novel Coronavirus in the Early Stage Non-severe vs severe symptomatic COVID-19: 104 cases from the outbreak on the cruise ship Clinical Characteristics And Risk Factors For Fatal Outcome in Patients With 2019-Coronavirus Infected Disease (COVID-19) in Wuhan Hospitalized Patients with 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Clinical Features of Patients Infected with the 2019 Novel Coronavirus (COVID-19 Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Clinical features and progression of acute respiratory distress syndrome in coronavirus disease 2019 Clinical Characteristics of Coronavirus Disease 2019 in China Analysis of factors associated with disease outcomes in hospitalized patients with Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China Radiographic Findings and other Predictors in Adults with Covid-19 Analysis of Death Risk Factors Among 200 COVID-19 Patients in Wuhan, China: A Hospital-Based Case-Cohort Study Characteristics of patients with COVID-19 during epidemic ongoing outbreak in Wuhan Clinical Characteristics of SARS-CoV-2 Infections Involving 325 Hospitalized Patients outside Wuhan Epidemiological Characteristics of 417 patients infected with COVID-19 and 368 discharged cases among them in Shenzhen City Correlation analysis between disease severity and clinical and biochemical characteristics of 143 cases of China: a descriptive study COVID-19, diabetes mellitus and ACE2: The conundrum The Effect of Short-Term Hyperglycemia on the Innate Immune System Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Activation of the GLP-1 receptor by liraglutide increases ACE2 expression, reversing right ventricle hypertrophy, and improving the production of SP-A and SP-B in the lungs of type 1 diabetes rats Contentious issues and evolving concepts in the clinical presentation and management of patients with COVID-19 infectionwith reference to use of therapeutic and other drugs used in Co-morbid diseases (Hypertension, diabetes etc) Angiotensin-converting enzyme 2 protects from severe acute lung failure The Dilemma of Coronavirus Disease 2019, Aging, and Cardiovascular Disease Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics Immune dysfunction in patients with diabetes mellitus (DM) COVID-19: consider cytokine storm syndromes and immunosuppression ≤40 (53%) CAD: [1] Although the majority of COVID-19 patients present with mild or no symptoms, some patients will develop severe pneumonia, acute respiratory distress syndrome (ARDS), multi-organ failure, and death.
    keywords: analysis; covid-19; disease; meta; outcome; patients
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        item: #3618 of 7819
          id: cord-298886-xidaim04
      author: Leszczyński, Piotr
       title: COVID-19: a short message to rheumatologists
        date: 2020-06-29
       words: 1573
      flesch: 30
     summary: Do patients with rheumatic diseases have a higher risk of being infected with SARS-CoV-2 virus and developing COVID-19 disease? In the first case in the analyzed group of patients with rheumatic diseases (n = 320), only four cases of COVID-19 disease were confirmed.
    keywords: covid-19; disease; patients; sars; treatment
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        item: #3619 of 7819
          id: cord-298894-t5hyfum3
      author: Rifino, Nicola
       title: Neurologic manifestations in 1760 COVID-19 patients admitted to Papa Giovanni XXIII Hospital, Bergamo, Italy
        date: 2020-10-07
       words: 4694
      flesch: 41
     summary: Although soon after all Italian regions reported patients with COVID-19, the highest number of cases was in Eastern Lombardy [2] , specifically in the Bergamo's province with 11,313 confirmed COVID-19 patients up to April 30th 2020 Patients with peripheral nervous system involvement had more frequently severe ARDS compared to patients with cerebrovascular disease (87.1% vs 42%; difference = 45.1% 95% CI 42.0–48.2; χ(2)= 14.306; p < 0.0002) and with altered mental status (87.1% vs 55.6%; difference = 31.5% 95% CI 27.5–37.5%; χ(2)= 7.055; p < 0.01).
    keywords: acute; cases; cov-2; covid-19; csf; disease; infection; involvement; patients; sars; study
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        item: #3620 of 7819
          id: cord-298899-lkrmg5qr
      author: Xie, Yewei
       title: Epidemiologic, clinical, and laboratory findings of the COVID-19 in the current pandemic: systematic review and meta-analysis
        date: 2020-08-31
       words: 6251
      flesch: 50
     summary: Download today's data on geographic distribution of COVID-19 cases worldwide Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region Clinical course and risk factors for mortality of adult in patients with COVID-19 in Wuhan, China: a retrospective cohort study Ethnicity and COVID-19: an urgent public health research priority COVID-19 sex-disaggregated data tracker-Sex, gender and COVID-19 Clinical features and outcomes of 98 patients hospitalized with SARS-CoV-2 infection in Daegu, South Korea: a brief descriptive study Early epidemiological and clinical manifestations of COVID-19 in Japan Clinical, radiological and therapeutic characteristics of patients with COVID-19 in Saudi Arabia Clinical course and potential predicting factors of pneumonia of adult patients with coronavirus disease 2019 (COVID-19): a retrospective observational analysis of 193 confirmed cases in Thailand Characteristics, risk factors and outcomes among the first consecutive 1096 patients diagnosed with COVID-19 in Kuwait Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO clinical characterization protocol: prospective observational cohort study Clinical characteristics of patients hospitalized with COVID-19 in Spain: results from the SEMI-COVID-19 network Epidemiology, risk factors and clinical course of SARS-CoV-2 infected patients in a Swiss university hospital: an observational retrospective study COVID-19 in Great Britain: epidemiological and clinical characteristics of the first few hundred (FF100) cases: a descriptive case series and case control analysis Clinical characteristics of coronavirus disease (COVID-19) early findings from a teaching hospital in Pavia Clinical and epidemiological characteristics of patients diagnosed with COVID-19 in a tertiary care center in Mexico CITY: a prospective cohort study Early experience with COVID-19 patients at academic hospital in southwestern United States Clinical characteristics and morbidity associated with coronavirus disease 2019 in a series of patients in metropolitan Detroit Clinical characteristics of Covid-19 in New York city Epidemiological and clinical characteristics of the early phase of the COVID-19 epidemic in Brazil Acute-onset smell and taste disorders in the context of COVID-19: a pilot multicentre polymerase chain reaction based case-control study Utility of hyposmia and hypogeusia for the diagnosis of COVID-19 Selfreported olfactory and taste disorders in patients with severe acute respiratory coronavirus 2 infection: a cross-sectional study COVID-19 anosmia reporting tool: initial findings Features of anosmia in COVID-19 Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China Smell dysfunction: a biomarker for COVID-19. In the US for example, the reasons that turned hospitals into infection hotspots included the overload of COVID-19 patients and inappropriate management against the pandemic in hospitals [29] .
    keywords: cases; characteristics; china; clinical; coronavirus; cov-2; covid-19; data; disease; novel; patients; sars; study; transmission
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        item: #3621 of 7819
          id: cord-298914-d6k3tagt
      author: Samuels, Elizabeth A.
       title: Innovation During COVID-19: Improving Addiction Treatment Access
        date: 2020-05-12
       words: 1283
      flesch: 34
     summary: A minority of the 2 million individuals with opioid use disorder living in the United States take opioid agonist medications for addiction treatment, despite clear evidence demonstrating reductions in all-cause mortality, opioid overdose, resumed opioid use, and HIV infections. While medication for opioid use disorder treatment has been expanded over recent years, 5 significant gaps in treatment availability remain.
    keywords: buprenorphine; disorder; opioid; treatment; use
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        item: #3622 of 7819
          id: cord-298915-g1u9jods
      author: Chen, Y.
       title: An Interpretable Machine Learning Framework for Accurate Severe vs Non-severe COVID-19 Clinical Type Classification
        date: 2020-05-22
       words: 4174
      flesch: 45
     summary: This study delivers an accurate diagnostic decision support tool to differentiate non-111 severe from severe type patients based on commonly available clinical data with clear clinical 112 interpretations. By more 304 extensive data mining we show that non-severe COVID-19 patients have many symptoms 305 differently distributed than severe patients.
    keywords: covid-19; data; features; license; medrxiv; patients; preprint; types
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        item: #3623 of 7819
          id: cord-298918-o1bmulz3
      author: Khosrawipour, Veria
       title: Failure in initial stage containment of global COVID‐19 epicenters
        date: 2020-04-28
       words: 1324
      flesch: 48
     summary: The present study included F I G U R E 1 Cumulative development of COVID-19 cases in China, South Korea, Japan, Italy, Germany, France, Spain, and Iran according to WHO data. Data for the months of January, February and March and magnification of latest case developments outside of China F I G U R E 2 Cumulative development of COVID-19 cases in China, South Korea, Japan, Italy, Germany, France, and Spain within the first and second 3-week intervals.
    keywords: cases; china; covid-19; data
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        item: #3624 of 7819
          id: cord-298925-4wb7kayl
      author: Ahmed, Sakir
       title: Moving towards online rheumatology education in the era of COVID-19
        date: 2020-09-17
       words: 4062
      flesch: 38
     summary: key: cord-298925-4wb7kayl authors: Ahmed, Sakir; Zimba, Olena; Gasparyan, Armen Yuri title: Moving towards online rheumatology education in the era of COVID-19 date: 2020-09-17 journal: Clin Rheumatol DOI: 10.1007/s10067-020-05405-9 sha: doc_id: 298925 cord_uid: 4wb7kayl • Online textbooks, didactic materials of indexed rheumatology journals, and frequently updated online educational hubs such as UpToDate serve as a foundation of online rheumatology education.
    keywords: countries; covid-19; education; journals; media; medical; pandemic; rheumatologists; rheumatology; training; uptodate
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        item: #3625 of 7819
          id: cord-298936-76xurcof
      author: Yanguas, Xavier
       title: Returning to Sport during the Covid-19 pandemic: The sports physicians’ role
        date: 2020-06-30
       words: 1457
      flesch: 28
     summary: Regarding professional athletes as the disease is relatively new, we do not have any substantial or meaningful data yet concerning the proportion or ratio of SARS-CoV-2 infection. As we mentioned previously, and even though a few related articles have been published, we do not know the exact magnitude of the disease in professional athletes nor its' real consequences and impact on physical performance 7, 10 .
    keywords: athletes; covid-19; football; health; sports
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        item: #3626 of 7819
          id: cord-298967-vjyh1xvh
      author: Bertossi, Dario
       title: Safety guidelines for non‐surgical facial procedures during covid‐19 outbreak
        date: 2020-06-07
       words: 2006
      flesch: 45
     summary: In our largely elective field, both staff and resources should ideally be allocated through careful protocols in order to prevent COVID-19 infection. In response to this pandemic, our focus group has developed a process to stratify procedures and clinical levels with protocols that aim to minimize the risk of contagion and the diffusion of COVID-19 infection.
    keywords: coronavirus; covid-19; guidelines; infection; patients; procedures; sars
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        item: #3627 of 7819
          id: cord-298991-5qae0ege
      author: Aiello, Francesco
       title: Coronavirus disease 2019 (SARS-CoV-2) and colonization of ocular tissues and secretions: a systematic review
        date: 2020-05-18
       words: 3152
      flesch: 45
     summary: Origin and evolution of pathogenic coronaviruses SARS-associated coronavirus Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China Identification of a novel coronavirus in patients with severe acute respiratory syndrome Koch's postulates fulfilled for SARS virus A novel coronavirus associated with severe acute respiratory syndrome Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the coronavirus study group Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical characteristics of coronavirus disease 2019 in China Note from the editors: World Health Organization declares novel coronavirus (2019-nCoV) sixth public health emergency of international concern Novel Coronavirus (2019-nCoV) Situation Report-22 Coronaviridae Study Group of the International Committee on Taxonomy of Viruses. Novel coronavirus (COVID-19) situation Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Enteric involvement of coronaviruses: is faecal-oral transmission of SARS-CoV-2 possible? Concentration and detection of SARS coronavirus in sewage from Xiao Tang Shan hospital and the 309th Hospital of the Chinese People's Liberation Army Identification of a new human coronavirus Human coronavirus NL63, France The severe acute respiratory syndrome coronavirus in tears
    keywords: conjunctival; conjunctivitis; coronavirus; cov-2; covid-19; patients; pcr; sars
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        item: #3628 of 7819
          id: cord-299018-eo73yl4v
      author: Gandini, O.
       title: Serum Ferritin as an independent risk factor for Acute Respiratory Distress Syndrome in COVID-19 Patients in Rome Italy
        date: 2020-09-15
       words: 759
      flesch: 28
     summary: Conversely, D dimer, LDH and CRP increased only in the group of critical patients (group 3), being substantially stable in the other groups characterized by mild, moderate and severe disease ( fig. 2 , panel C, D, E) Multivariate logistic regression model adjusted for several disease-related risk factors at admission, including age, sex, NLR, DD, LDH, ferritin and CRP, demonstrated that serum ferritin resulted as an independent predictor of disease severity in COVID-19 patients (OR = 1,0048, 95% CI, 1,0029 to 1,0083, P < 0,001.). In this Journal, Zhi Lin and colleagues (1) recently reported that Chinese patients with severe Sars-CoV2 disease showed higher levels of serum ferritin than patients with not severe one, confirming data from other authors on Chinese (2) (3) and Caucasian populations (4) (5) .
    keywords: covid-19; ferritin; patients
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        item: #3629 of 7819
          id: cord-299021-dbu05gyy
      author: Semedo, Edimir
       title: Drug-induced ‘Torsade de Pointes’ in a COVID-19 patient despite discontinuation of chloroquine. Importance of its long half-life: a case report
        date: 2020-07-21
       words: 1901
      flesch: 44
     summary: Reversible causes of QT interval prolongation were investigated. Chloroquine can cause significant QT interval prolongation, increasing the risk of life-threatening cardiac arrhythmias, especially TdP.
    keywords: chloroquine; covid-19; day; interval; qtc; treatment
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        item: #3630 of 7819
          id: cord-299025-9bcploh4
      author: Dean, Preston
       title: The impact of public health interventions on critical illness in the pediatric emergency department during the SARS‐CoV‐2 pandemic
        date: 2020-08-10
       words: 2410
      flesch: 42
     summary: key: cord-299025-9bcploh4 authors: Dean, Preston; Zhang, Yin; Frey, Mary; Shah, Ashish; Edmunds, Katherine; Boyd, Stephanie; Schwartz, Hamilton; Frey, Theresa; Stalets, Erika; Schaffzin, Joshua; Vukovic, Adam A.; Reeves, Scott; Masur, Tonya; Kerrey, Benjamin title: The impact of public health interventions on critical illness in the pediatric emergency department during the SARS‐CoV‐2 pandemic date: 2020-08-10 journal: J Am Coll Emerg Physicians Open DOI: 10.1002/emp2.12220 sha: doc_id: 299025 cord_uid: 9bcploh4 STUDY OBJECTIVE: The impact of public health interventions during the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic on critical illness in children has not been studied.
    keywords: covid-19; emergency; health; illness; interventions; pandemic; visits
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        item: #3631 of 7819
          id: cord-299044-j7txbt1n
      author: Gravas, Stavros
       title: Impact of COVID-19 on medical education: introducing homo digitalis
        date: 2020-08-29
       words: 2699
      flesch: 49
     summary: Results were analyzed to examine the influence of age, practice region and settings on continuing medical education (CME) of the respondents. This requires ongoing participation in continuing medical education (CME) and a habit of lifelong learning.
    keywords: covid-19; education; learning; media; methods; urologists
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        item: #3632 of 7819
          id: cord-299082-s8bm40vy
      author: Wang, Yueying
       title: Cardiac arrhythmias in patients with COVID‐19
        date: 2020-07-26
       words: 3724
      flesch: 31
     summary: An example of reversible electrical storm Incessant monomorphic ventricular tachycardia during febrile illness in a patient with Brugada syndrome: fatal electrical storm Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure Fever increases the risk for cardiac arrest in the Brugada syndrome Hyperthermia influences the effects of sodium channel blocking drugs in human-induced pluripotent stem cell-derived cardiomyocytes Controversies of renin-angiotensin system inhibition during the COVID-19 pandemic Antihypertensive treatment with ACEI/ARB of patients with COVID-19 complicated by hypertension Angiotensin II and angiotensin 1-7: which is their role in atrial fibrillation? CaMKII as a target for arrhythmia suppression Angiotensin II signal transduction: an update on mechanisms of physiology and pathophysiology COVID-19-related severe hypercoagulability in patients admitted to intensive care unit for acute respiratory failure Cardiac and arrhythmic complications in patients with COVID-19 Cardiac arrhythmias in acute coronary syndromes: position paper from the joint EHRA, ACCA, and EAPCI task force Calcium-calmodulin dependent protein kinase II (CaMKII): a main signal responsible for early reperfusion arrhythmias Acute regional left atrial ischemia causes acceleration of atrial drivers during atrial fibrillation Mechanisms of atrial tachyarrhythmias associated with coronary artery occlusion in a chronic canine model Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current If: Novel electrophysiological insights and therapeutic potential Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro Electrophysiologic studies on the risks and potential mechanism underlying the proarrhythmic nature of azithromycin Azithromycin causes a novel proarrhythmic syndrome Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Multilead QT screening is necessary for QT measurement: implications for management of patients in the COVID-19 era Inpatient use of mobile continuous telemetry for COVID-19 patients treated with hydroxychloroquine and azithromycin Expert recommendations for clinical management of myocardial injury associated with coronavirus disease Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Breakthrough: chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies COVID-19) This is followed by a discussion on the underlying mechanisms, with proposals of preventative and therapeutic strategies for treating cardiac arrhythmias in COVID-19 patients.
    keywords: acute; arrhythmias; azithromycin; cardiac; clinical; coronavirus; covid-19; patients; sars; syndrome
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        item: #3633 of 7819
          id: cord-299093-zp07aqpm
      author: Harrison, Andrew G.
       title: Mechanisms of SARS-CoV-2 transmission and pathogenesis
        date: 2020-10-14
       words: 6401
      flesch: 34
     summary: A first step in understanding SARS pathogenesis A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues Atlas of ACE2 gene expression in mammals reveals novel insights in transmission of SARS-CoV-2 A Transmembrane Serine Protease Is Linked to the Severe Acute Respiratory Syndrome Coronavirus Receptor and Activates Virus Entry Single-cell RNA expression profiling of ACE2, the receptor of SARS-CoV-2 Angiotensin-converting enzyme 2 protects from severe acute lung failure Endocytosis of the receptor-binding domain of SARS-CoV spike protein together with virus receptor ACE2 Cigarette smoke exposure and inflammatory signaling increase the expression of the SARS-CoV-2 receptor ACE2 in the respiratory tract Furin cleavage of the SARS coronavirus spike glycoprotein enhances cell-cell fusion but does not affect virion entry SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa Virological assessment of hospitalized patients with COVID-2019 Epidemiology, Genetic Recombination, and Pathogenesis of Coronaviruses The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes High Prevalence of Concurrent Gastrointestinal Manifestations in Patients with SARS-CoV-2: Early Experience from California Evidence for Gastrointestinal Infection of SARS-CoV-2 Enteric involvement of severe acute respiratory syndromeassociated coronavirus infection Evidence of Airborne Transmission of the Severe Acute Respiratory Syndrome Virus Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination Role of air distribution in SARS transmission during the largest nosocomial outbreak in Hong Kong Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients Viral load of SARS-CoV-2 in clinical samples Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship CT imaging and clinical course of asymptomatic cases with COVID-19 pneumonia at admission in Wuhan Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany The clinical feature of silent infections of novel coronavirus infection (COVID-19) in Wenzhou Possible modes of transmission of Novel coronavirus SARS-CoV-2: a review SARS: experience at Prince of Wales Hospital, Hong Kong Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 Air, Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding A Novel Coronavirus Associated with Severe Acute Respiratory Syndrome Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Outcomes of Cardiovascular Magnetic Resonance Imaging in Patients Recently Recovered From Coronavirus Disease 2019 (COVID-19) Clinical Characteristics and Outcomes of Hospitalized and Critically Ill Children and Adolescents with Coronavirus Disease 2019 (COVID-19) at a Tertiary Care Medical Center The Twilight of Immunity: Emerging Concepts in Aging of the Immune System Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2 Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Clinical characteristics of COVID-19 in 104 people with SARS-CoV-2 infection on the Diamond Princess cruise ship: a retrospective analysis Clinical characteristics of 82 cases of death from COVID-19 Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Clinical features of COVID-19 in elderly patients: A comparison with young and middle-aged patients Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses Cellular Immune Responses to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection in Senescent BALB/c Mice: CD4+ T Cells Are Important in Control of SARS-CoV Infection Evasion by Stealth: Inefficient Immune Activation Underlies Poor T Cell Response and Severe Disease in SARS-CoV-Infected Mice Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19 Dysregulation of immune response in patients with COVID-19 in Wuhan, China Imbalanced host response to SARS-CoV-2 drives development of COVID-19 SARS-CoV-2 activates lung epithelia cell proinflammatory signaling and leads to immune dysregulation in COVID-19 patients by single-cell sequencing The clinical pathology of severe acute respiratory syndrome (SARS): a report from China Lung pathology of fatal severe acute respiratory syndrome Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Cytokine release syndrome in severe COVID-19 Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology C-reactive protein: Ligands, receptors and role in inflammation Neutrophil extracellular traps in COVID-19 Endothelial cell infection and endotheliitis in COVID-19 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients Regulation of IRF-3 dependent innate immunity by the Papainlike protease domain of the SARS coronavirus Severe Acute Respiratory Syndrome Coronavirus Papain-Like Protease Ubiquitin-Like Domain and Catalytic Domain Regulate Antagonism of IRF3 and NF-κB Signaling Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling Activation and evasion of type I interferon responses by SARS-CoV-2 Severe acute respiratory syndrome coronavirus protein nsp1 is a novel eukaryotic translation inhibitor that represses multiple steps of translation initiation Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic Origin Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2 Evasion of type- Indeed, similar inflammatory milieux have been associated with severe lung pathology in SARS patients, along with the notable 'cytokine storm' that can present in critically ill COVID-19 patients [83, 84]
    keywords: ace2; cell; coronavirus; cov-2; covid-19; disease; human; infection; lung; patients; respiratory; sars; syndrome; transmission
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        item: #3634 of 7819
          id: cord-299099-e1ajjte6
      author: Brunese, Luca
       title: Machine learning for coronavirus covid-19 detection from chest x-rays
        date: 2020-12-31
       words: 3101
      flesch: 50
     summary: As stated in [13, 2] COVID-19 is possibly better diagnosed using radiological imaging, for this reason in this paper we evaluate the possibility to detect the COVID-19 disease directly from x-ray images. The training phase is aimed to build a model for discriminating between x-rays images COVID-19 related and images related to other pathologies.
    keywords: covid-19; detection; disease; feature; patients; set
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        item: #3635 of 7819
          id: cord-299102-4bwtg6xz
      author: Novara, Giacomo
       title: Impact of the COVID‐19 pandemic on urological practice in emergency departments in Italy
        date: 2020-05-30
       words: 1592
      flesch: 39
     summary: Following the emergency department consultation, a similar percentage of patients was hospitalized for urological conditions (22% and 25% in the 2020 and 2019 weeks, respectively). Thirdly, the patients who arrived at hospital were significantly older and had a slightly different spectrum of urological conditions, including more cases of gross haematuria and acute urinary retention, conditions commonly considered as undeferrable.
    keywords: covid-19; emergency; pandemic; patients
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        item: #3636 of 7819
          id: cord-299104-kb5gsig5
      author: Riou, Marianne
       title: Clinical characteristics of and outcomes for patients with COVID-19 and comorbid lung diseases primarily hospitalized in a conventional pulmonology unit: a retrospective study
        date: 2020-11-12
       words: 3627
      flesch: 41
     summary: A Nationwide Analysis Prevalence of Underlying Diseases in Hospitalized Patients with COVID-19: a Systematic Review and Meta-Analysis Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 -COVID-NET, 14 States Detection of asthma and chronic obstructive pulmonary disease in primary care Changes in medication adherence among patients with asthma and COPD during the Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2 ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 Autoimmune Responses in Severe Asthma Therapeutic potential of ciclesonide inahalation for COVID-19 pneumonia: However, a tendency to higher global mortality was observed in COVID-19 patients with CLD.
    keywords: asthma; cld; copd; covid-19; disease; icu; lung; patients; risk
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        item: #3637 of 7819
          id: cord-299107-0rd2uj4r
      author: Kadi, Nadjat
       title: Population density, a factor in the spread of COVID-19 in Algeria: statistic study
        date: 2020-08-20
       words: 2026
      flesch: 46
     summary: In this research, we endorse population density as a catalyst factor for the proliferation of COVID-19 in Algeria. We are interested in the relationship between population density and the spread of COVID-19 in Algerian cities.
    keywords: covid-19; density; population; population density
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        item: #3638 of 7819
          id: cord-299116-1agfnjvq
      author: Bunders, Madeleine
       title: Implications of sex differences in immunity for SARS-CoV-2 pathogenesis and design of therapeutic interventions
        date: 2020-08-17
       words: 6274
      flesch: 24
     summary: Increasing data demonstrates that women mount stronger immune responses against viruses and vaccines (Flanagan et al., 2017; Klein and Flanagan, 2016; Ziegler and Altfeld, 2017) , and also exhibit superior immune-mediated tissue repair capacities (Vom Steeg and Klein, 2019) . In general, women develop stronger innate and adaptive immune responses against most viral infections and vaccines (Flanagan et al., 2017; Klein and Flanagan, 2016) , and significant sex differences in the induction of type I IFN responses, B cell functions and T cell functions have been described.
    keywords: ace2; cells; cov-2; covid-19; differences; et al; immune; infection; patients; responses; sars; sex; tissue; women
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        item: #3639 of 7819
          id: cord-299139-ze8qtnxe
      author: Higbee, D. H.
       title: The impact of asthma on mental health & wellbeing during COVID-19 lockdown
        date: 2020-09-11
       words: 5043
      flesch: 52
     summary: In addition to the absolute mental health scores in participants with asthma vs. without asthma, we examined the expected difference in mental health scores during COVID-19 between participants with asthma and without asthma, after adjusting for pre-existing mental health, gender, age, is the author/funder, who has granted medRxiv a license to display the preprint in (which was not certified by peer review) preprint The copyright holder for this this version posted September 11, 2020. . During COVID-19 mental health worsened in both groups, but there was a greater decline to a lower level in those with asthma.
    keywords: alspac; anxiety; asthma; covid-19; medrxiv; participants; preprint
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        item: #3640 of 7819
          id: cord-299141-vxvqs5kh
      author: Ma, Xiao-Peng
       title: Prevention program for the COVID-19 in a children’s digestive endoscopy center
        date: 2020-04-26
       words: 2899
      flesch: 36
     summary: Digestive endoscopy is an invasive procedure during which children cannot wear masks; therefore, they have higher risks of exposure to COVID-19, and the digestive endoscopy center is a relatively high-risk area for COVID-19 infection. Digestive endoscopy is an invasive procedure during which children cannot wear masks; therefore, they have higher risks of exposure to COVID-19, and the digestive endoscopy center is a relatively high-risk area for COVID-19 infection.
    keywords: children; covid-19; disinfection; endoscopy; infection; medical; staff
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        item: #3641 of 7819
          id: cord-299144-yprqlgju
      author: Lin, Shaowei
       title: Region-specific air pollutants and meteorological parameters influence COVID-19: A study from mainland China
        date: 2020-08-05
       words: 4113
      flesch: 36
     summary: The correlations of R 0 and meteorological data, air quality data were described by Pearson Correlation Coefficient (r), or Spearman Correlation Coefficient (r s , if the data were not normally distributed), and the trend of R 0 with meteorological factors and air quality factors was plotted. We conducted an observational study on the correlation between COVID-19 and ecological indicators such as meteorological parameters and air quality, reflecting the most comprehensive study to date on the role of meteorological parameters and air quality factors in COVID-19.
    keywords: air; correlation; covid-19; factors; flow; quality; study
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        item: #3642 of 7819
          id: cord-299155-94jplecb
      author: Sharma, Dhruva
       title: Rationale of anticoagulation among patients of COVID-19 undergoing cardiac surgery
        date: 2020-07-21
       words: 656
      flesch: 33
     summary: Moreover, autopsy studies have also registered evidence of macro as well as micro embolism in patients with COVID-19 infection However, Tremblay et al. performed a propensity-matched analysis of patients who were on empiric antithrombotic therapy prior to COVID-19 infection which was compared with those who were on neither anticoagulant nor antiplatelet therapy.
    keywords: covid-19; patients
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        item: #3643 of 7819
          id: cord-299156-1dwsm3ie
      author: Shemer, Asaf
       title: Ocular involvement in coronavirus disease 2019 (COVID-19): a clinical and molecular analysis
        date: 2020-09-14
       words: 3521
      flesch: 52
     summary: It should also be noted that when COVID-19 patients were questioned on redness or discharge in the 30 days prior to admission, five (Patients #2, #3 and three additional patients) responded positively (compared to none in the control group, p = 0.001, Table 3 ). COVID-19 patients were clinically categorized to mild, moderate or severe on a daily basis according to a risk assessment calculated using the Modified Early Warning Score (MEWS)
    keywords: conjunctival; cov-2; covid-19; disease; patients; sars
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        item: #3644 of 7819
          id: cord-299159-cxktdaws
      author: Boelig, Rupsa C.
       title: MFM Guidance for COVID-19
        date: 2020-03-19
       words: 627
      flesch: 43
     summary: The goals the guidelines put forth here are two fold- first to reduce patient risk through healthcare exposure, understanding that asymptomatic health systems/healthcare providers may become the most common vector for transmission, and second to reduce the public health burden of COVID-19 transmission throughout the general population. The goals the guidelines put forth here are two fold-22 first to reduce patient risk through healthcare exposure, understanding that asymptomatic health 23 systems/healthcare providers may become the most common vector for transmission, and second to 24 reduce the public health burden of COVID-19 transmission throughout the general population.
    keywords: covid-19; section
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        item: #3645 of 7819
          id: cord-299237-pdkxqf3h
      author: Pericàs, Juan M
       title: Profile and quality of published reviews on COVID‐19
        date: 2020-05-30
       words: 858
      flesch: 39
     summary: Scientific journals have timely responded to this challenge by prioritizing COVID-19 research, with proactive editorial efforts favoring open-access to articles, launching calls for papers, implementing specific sections and special issues on COVID-19, among others. Secondly, a generally poor methodological appraisal of reviews was found, as shown by the low proportion of studies providing the search strategy, the low number of systematic reviews and the low percentage of these following PRISMA 5 and GRADE 6 principles.
    keywords: covid-19; research; reviews
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        item: #3646 of 7819
          id: cord-299261-ew99nraq
      author: Cipriano, L. E.
       title: IMPACT OF UNIVERSITY RE-OPENING ON TOTAL COMMUNITY COVID-19 BURDEN
        date: 2020-09-18
       words: 9224
      flesch: 37
     summary: Furthermore, while some of these studies did include infections among students arising from offcampus community contact, these studies did not consider the impact of university student infections and university administration prevention and management decisions on the broader community in which that campus is situated. Through the many interactions between the student population and the city in which they reside, COVID-19 mitigation policies targeted at university student communities and adopted by university leaders may have substantial public health implications for those in the surrounding community.
    keywords: care; community; contacts; covid-19; infections; license; number; population; preprint; students; testing; university
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        item: #3647 of 7819
          id: cord-299274-gnbp7so5
      author: Bodkin, Claire
       title: Pandemic Planning in Homeless Shelters: A pilot study of a COVID-19 testing and support program to mitigate the risk of COVID-19 outbreaks in congregate settings
        date: 2020-06-08
       words: 1644
      flesch: 48
     summary: Furthermore, the higher prevalence of comorbidities amongst shelter residents places them at higher risk of severe COVID-19 disease (5) . No specific limitations were imposed upon shelter residents during the study period although movement between shelters was discouraged.
    keywords: covid-19; residents; shelter; staff
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        item: #3648 of 7819
          id: cord-299277-ana68vpf
      author: Horn, Sarah R.
       title: Identifying causal role of COVID-19 in immunopsychiatry models
        date: 2020-05-29
       words: 1340
      flesch: 36
     summary: Geographic Differences in COVID-19 Cases, Deaths, and Incidence-United States Evidence supporting transmission of severe acute respiratory syndrome coronavirus 2 while presymptomatic or asymptomatic Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science Neuroticism and Emotional Risk During the Covid-19 Pandemic Lavaan: An R package for structural equation modeling and more. Under these circumstances, causal models in immunopsychiatry will, for the foreseeable future, need to account for COVID-19.
    keywords: causal; covid-19; effect; models
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        item: #3649 of 7819
          id: cord-299308-gza1pwx6
      author: Laxminarayan, Ramanan
       title: Is Gradual and Controlled Approach to Herd Protection a Valid Strategy to Curb the COVID-19 Pandemic?
        date: 2020-05-06
       words: 1558
      flesch: 47
     summary: Globally, there are two broad approaches to taming the epidemic: by imposing lockdowns and other forced physical distancing measures to 'flatten the curve',or allowing 'herd immunity' by allowing for a graded acquisition of immunity. The epidemic will decline when herd immunity reaches sufficient level, determined by calculation based on the basic reproduction number, Ro.
    keywords: covid-19; herd; immunity; sars
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        item: #3650 of 7819
          id: cord-299309-p703e396
      author: Tan-Torres Edejer, Tessa
       title: Projected health-care resource needs for an effective response to COVID-19 in 73 low-income and middle-income countries: a modelling study
        date: 2020-09-09
       words: 5161
      flesch: 48
     summary: 7 Capital costs included within the resource needs for COVID-19 response are intended for upgrading laboratories for diagnostic testing (pillar 5), buying field hospitals to expand capacity for treating COVID-19 patients (pillar 7), and repurposing health facilities to enable them to cope with non-COVID-19 patients who would otherwise have been treated in hospitals providing care to COVID-19 patients (pillar 9) to lift the supply side constraint of hospital and intensive care unit beds, procuring communications equipment (pillar 1), and providing motorcycles for contact-tracing teams (pillar 3; table 1). To maintain essential health services, salaries were paid to new hires to replace half of the number of existing health workers prioritised for COVID-19 response, on the assumption that 100% replacement was not needed because non-urgent consul tations and elective admissions are being postponed.
    keywords: costs; countries; covid-19; health; income; quo; response; scenario; status; transmission; weeks
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        item: #3651 of 7819
          id: cord-299312-asc120pn
      author: Khoshnaw, Sarbaz H.A.
       title: A Quantitative and Qualitative Analysis of the COVID–19 Pandemic Model
        date: 2020-05-25
       words: 2087
      flesch: 29
     summary: We have applied the idea of local sensitivity to calculate the sensitivity 525 of each model state concerning model parameters for the updated model of the COVID-19. Results based on the computational simulations show that the model dynamics are significantly changed for different key model parameters.
    keywords: coronavirus; covid-19; model; parameters
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        item: #3652 of 7819
          id: cord-299324-0hzlvwfn
      author: Koeberle, Séverine
       title: COVID 19 outbreak: organisation of a geriatric assessment and coordination unit. A French example
        date: 2020-05-06
       words: 3825
      flesch: 31
     summary: • CFS 7 to 9: Decision-making support for therapeutic limitation with palliative support either at the place of residence (in telephone contact with the mobile palliative care team), or a decision to be hospitalised in a dedicated COVID palliative care unit Once the level of care has been determined, the resulting orientation for follow-up is at one of four levels: • COVID negative or non-suspect patients, but requiring geriatric care, or at least geriatric advice, in particular because of difficulties in home care secondary to the reduction in healthcare services: preservation of a 'traditional' geriatric admission pathway, or maintenance of a 'traditional' home care system with the introduction/adaptation of home care if necessary, in connection with regional health authorities in order to have a vision of the health resources that can be mobilised. (ii) Individual support to define appropriate levels of care: (a) Allow discussions, on a case-by-case basis, to determine the required levels of care for people aged 75 and over; (b) Allow diagnostic or therapeutic management assistance if necessary; (c) Provide assistance in guiding these patients through the care pathway by providing real-time monitoring of the care pathways throughout the territory; (d) Encourage the appropriate use of traditional geriatric networks for COVID negative patients needing geriatric care, after assessment of clinical needs and available resources for outpatient or inpatient management. (iii) Coordination between stakeholders: To allow the transmission of information between the different actors such as the medical regulation centre (centre 15), general practitioners, nursing homes and hospitals, hygienists, palliative care physicians and geriatricians.
    keywords: care; covid; geriatric; hospital; level; organisation; palliative; unit
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        item: #3653 of 7819
          id: cord-299326-uqwkhczx
      author: Tang, Chong
       title: Clinical Characteristics of 20,662 Patients with COVID-19 in mainland China: A Systemic Review and Meta-analysis
        date: 2020-04-23
       words: 4285
      flesch: 49
     summary: The second most common symptom was cough, and approximately one-quarter of COVID-19 patients produced sputum. The clinical characteristics of COVID-19 patients at admission are changing Clinical and Laboratory Profiles of 75 Hospitalized Patients with Novel Coronavirus Disease Clinical characteristics of 101 non-surviving hospitalized patients with COVID-19-A single center, retrospective study.
    keywords: author; covid-19; funder; license; medrxiv; patients; preprint; review
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        item: #3654 of 7819
          id: cord-299333-qu0bmov5
      author: Reddy, Gireesh B.
       title: Clinical Characteristics and Multisystem Imaging Findings of COVID-19: An Overview for Orthopedic Surgeons
        date: 2020-08-17
       words: 4421
      flesch: 28
     summary: The most common abdominal imaging findings in COVID-19 ICU patients include small and large bowel wall thickening, non-enhancing bowel, pneumatosis, portal venous gas, and bowel perforation, all related to bowel and mesenteric ischemia, infarction, and necrosis ( Fig. 14) In addition to the widely known pulmonary symptoms, COVID-19 patients may initially present with atypical neurologic, gastrointestinal, cardiac, and musculoskeletal imaging findings (Table 1) , which are more likely to be undiagnosed.
    keywords: acute; coronavirus; covid-19; disease; findings; imaging; manifestations; patients; pulmonary; symptoms; syndrome
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        item: #3655 of 7819
          id: cord-299346-f13xly6q
      author: Awad, Mohamed E.
       title: Perioperative Considerations in Urgent Surgical Care of Suspected and Confirmed Coronavirus Disease 2019 Orthopaedic Patients: Operating Room Protocols and Recommendations in the Current Coronavirus Disease 2019 Pandemic
        date: 2020-04-10
       words: 4218
      flesch: 35
     summary: Our recommendations for using face masks and respirators varies depending on the setting and activity ( ½T1 Table 1 Of note, the regular surgical helmet cannot replace the need of respirator while operating on suspected/ confirmed COVID-19 patients. [15] A recent study investigating SARS-CoV-2 from clinical specimens found that RNA virus detected in blood samples from confirmed COVID-19 patients (3 of 307; 1%).
    keywords: care; contamination; coronavirus; covid-19; disease; face; pandemic; patients; ppe; risk; use
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        item: #3656 of 7819
          id: cord-299350-db8w79g8
      author: Gibson, Cody V.
       title: Emergency Medical Services resource capacity and competency amid COVID-19 in the United States: Preliminary findings from a national survey
        date: 2020-05-03
       words: 2370
      flesch: 41
     summary: Providers who report their employer would compensate them if quarantined: 30% Social distancing practices: -33% report their facility recommends social distancing practices -15% report their facility requires social distancing practices -52% report their facility has no policy regarding social distancing practices Providers who would consider continuing to work and treat patients if tested positive for COVID-19 or experiencing COVID-19 like signs or symptoms: 36% As reflected in Table 4 , the majority of EMS providers report the use of nitrile gloves during regular EMS operations. An overwhelming number of EMS providers report having limited access to N95 respirators, receiving little or no benefits from COVID-19 related work, and report no institutional policy on social distancing practices despite CDC recommendations.
    keywords: covid-19; ems; patient; providers; report
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        item: #3657 of 7819
          id: cord-299375-ve4lag21
      author: Yang, Yichang
       title: Use of herbal drugs to treat COVID-19 should be with caution
        date: 2020-05-15
       words: 929
      flesch: 41
     summary: key: cord-299375-ve4lag21 authors: Yang, Yichang title: Use of herbal drugs to treat COVID-19 should be with caution date: 2020-05-15 journal: Lancet DOI: 10.1016/s0140-6736(20)31143-0 sha: doc_id: 299375 cord_uid: ve4lag21 nan On April 14, 2020, a Chinese official announced at a press conference that indications of three patent herbal drugs were approved to be expanded to include COVID-19 symptoms. So far, no high-quality, rigorously peerreviewed clinical trials of herbal drugs have been reported in internationally recognised journals.
    keywords: covid-19; drugs; medicine
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        item: #3658 of 7819
          id: cord-299407-wuug8jjv
      author: Ahlers-Schmidt, Carolyn R.
       title: Concerns of Women regarding Pregnancy and Childbirth during the COVID-19 Pandemic
        date: 2020-09-24
       words: 1991
      flesch: 45
     summary: Due to COVID-19 women also reported decreased likelihood of talking to doctor about medications and mental health concerns. Other infant care behavior changes included limiting contact with infant, scheduling appointments to avoid sick patients and taking precautions such as hand washing and protective barriers when leaving the house.
    keywords: changes; covid-19; pandemic; participants; women
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        item: #3659 of 7819
          id: cord-299465-c7ki3061
      author: Mallow, P. J.
       title: When Second Best Might be the Best: Using Hospitalization Data to Monitor the Novel Coronavirus Pandemic
        date: 2020-05-18
       words: 1682
      flesch: 45
     summary: As a lagging indicator, COVID-19 hospitalizations would normally be considered a second-best solution to measuring a trend in the infection rate. However, given the sample bias reflected in prioritized testing and asymptomatic transmission, we propose that COVID-19 hospitalizations combined with a capacity measure offer the best approach to measuring trends in COVID-19 infections.
    keywords: coronavirus; covid-19; license; novel; preprint
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        item: #3660 of 7819
          id: cord-299469-lqro7t7a
      author: Tan, Eng-King
       title: Neurological research & training after the easing of lockdown in countries impacted by COVID-19
        date: 2020-08-24
       words: 1295
      flesch: 31
     summary: However, staff capacity remains an issue specifically where investigators have been deployed to COVID-19 studies while older and more vulnerable researchers are assigned to non-clinical support facilities. The opening of non-COVID-19 related clinical trials brings forth its own challenges.
    keywords: countries; covid-19; patients; research; trials
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        item: #3661 of 7819
          id: cord-299495-1z4udo3d
      author: Rajendram, Rajkumar
       title: Identifying phenotypes of COVID-19, defining their pathogenesis, and targeting treatments could improve outcomes
        date: 2020-06-24
       words: 907
      flesch: 38
     summary: Defining the incidence of PE, intra-pulmonary shunt, pulmonary arterio-venous malformations, PFO, atrial septal defects and atrial septal aneurysms in patients with phenotype 1 and Type L COVID-19 would greatly advance the understanding of the pathogenesis of COVID-19. This may represent increased intra-pulmonary shunt (IPS) due to pulmonary endothelial dysfunction and dysregulated hypoxic vasoconstriction (Gattinoni et al., 2020a; 2020b) .
    keywords: covid-19
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        item: #3662 of 7819
          id: cord-299499-66qh3r75
      author: Guilamo-Ramos, Vincent
       title: Reconsidering assumptions of adolescent and young adult SARS-CoV-2 transmission dynamics
        date: 2020-09-07
       words: 4203
      flesch: 31
     summary: Research indicates families-parents, in particular-matter in relation to AYA health behavior [32] . Specific guidance for parents regarding communication and monitoring strategies that positively influence AYA health behavior in the context of COVID-19 is sorely needed.
    keywords: aya; cov-2; covid-19; health; sars; testing; transmission; years
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        item: #3663 of 7819
          id: cord-299501-07echrdh
      author: Ould Setti, M.
       title: Social Distancing with Movement Restrictions and the Effective Replication Number of COVID-19: Multi-Country Analysis Based on Phone Mobility Data
        date: 2020-10-12
       words: 3240
      flesch: 44
     summary: The object of this study is to analyze how patterns of mobility data can be linked to COVID-19 Rt changes in 125 countries with and without consideration of SI. Through a timeseries regression study, we examined how mobility patterns from aggregated mobile phones data relate to the variation of COVID-19 Rt in 125 countries during the period from February 15 to September 11, 2020.
    keywords: countries; covid-19; data; group; mobility; preprint
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        item: #3664 of 7819
          id: cord-299544-r3cqvf0c
      author: de Souza, T. H.
       title: Clinical Manifestations of Children with COVID-19: a Systematic Review
        date: 2020-04-03
       words: 2587
      flesch: 50
     summary: A total of 1112 descriptions of pediatric cases 3,5,10-37 and 6 neonate cases 38-41 of COVID-19 were obtained, being that 639 were males 477 were females, and 2 were not disclosed. Since COVID-19 has a favorable clinical course in children, the importance of pediatric cases is mainly due to epidemiological issues.
    keywords: cases; children; clinical; coronavirus; covid-19; preprint
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        item: #3665 of 7819
          id: cord-299547-9i8kv8p8
      author: Aucejo, Esteban M.
       title: The Impact of COVID-19 on Student Experiences and Expectations: Evidence from a Survey
        date: 2020-08-27
       words: 5276
      flesch: 47
     summary: We are interested in the causal impact of COVID-19 on student outcomes: where the first term on the right-hand side is student i 's outcome in the state of the world with COVID-19, and the second term being student 6 The better performance on admission tests could be explained by the high proportion of Honors students in our sample (22% compared to 18% in the ASU population).
    keywords: covid-19; effects; graduation; health; income; outcomes; students
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        item: #3666 of 7819
          id: cord-299567-tlnvqah3
      author: Irfan, M.
       title: The psychological impact of coronavirus on university students and its socio-economic determinants in Malaysia
        date: 2020-10-30
       words: 4826
      flesch: 54
     summary: This article examines the impact of coronavirus disease 2019 (COVID-19) upon university students anxiety level and finds the factors associated with the anxiety disorder in Malaysia. It was discovered that having a physical condition and concerns relating to the epidemic were positively associated with anxiety levels.
    keywords: anxiety; covid-19; level; license; medrxiv; preprint; students
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        item: #3667 of 7819
          id: cord-299570-1xz5r95f
      author: Martínez-García, M
       title: Telemedicina con telemonitorización en el seguimiento de pacientes con COVID-19
        date: 2020-06-05
       words: 1611
      flesch: 50
     summary: Sanitaria de Lugo entre el 17 de marzo y el 17 de abril de 2020. Entendemos que este sistema ha contribuido a que el flujo de pacientes fuese ordenado y a que las visitas espontáneas a Urgencias hayan sido la excepción.
    keywords: con; covid-19; los; pacientes; patients; que; seguimiento
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        item: #3668 of 7819
          id: cord-299599-y18iv3zq
      author: Ojinnaka, Chinedum O.
       title: Factors Associated with COVID-Related Mortality: the Case of Texas
        date: 2020-11-09
       words: 3251
      flesch: 39
     summary: We also observed an inverse relationship between the probability of COVID-19 fatality and rate of primary care physicians, aligning with earlier reports that Texas counties with case fatality rates greater than 10% also had the lowest number of primary care physicians per 100,000 [28] . A total of four models were estimated as follows: (i) logistic regression model with COVID-19 related fatality (0/1) as the dependent variable, and proportion of racial/ethnic groups as the only independent variables; (ii) logistic regression model with COVID-19 related fatality (0/1) as the dependent variable, and proportion of racial/ethnic groups + healthcare access measures + other demographic characteristics as the independent variables; (iii) generalized linear models with fatalities per 100,000 population as the dependent variable and proportion of racial/ethnic groups alone as the only independent variables; and (iv) generalized linear models with fatalities per 100,000 population as the dependent variable and proportion of racial/ethnic groups + healthcare access measures + other demographic characteristics as the independent variables.
    keywords: americans; county; covid-19; health; level; racial; texas
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        item: #3669 of 7819
          id: cord-299613-5ju5fcf4
      author: Arthi, Vellore
       title: Disease, downturns, and wellbeing: Economic history and the long-run impacts of COVID-19
        date: 2020-11-03
       words: 17514
      flesch: 39
     summary: Although urban centers were associated with higher pandemic mortality, the opposite population gradient prevailed when comparing among cities, or among rural areas: in both cases, smaller, less dense localities fared worse (Acuna-Soto et al., 2011; Chowell et al., 2008) , suggestive perhaps of capacity constraints in the healthcare workforce and medical infrastructure. Likewise, foreign-born status not only predicted higher pandemic mortality in Hartford, Connecticut, but the relationship between nativity and mortality persisted even after controlling for socioeconomic status, population density, and neighborhood ethnic composition, indicating perhaps a role for social factors, or language or cultural barriers to the adoption of relevant public health measures (Tuckel et al., 2006) .
    keywords: 1918; covid-19; crisis; data; disease; effects; et al; evidence; exposure; health; history; human; income; individuals; influenza; influenza pandemic; instance; labor; market; mortality; pandemic; past; population; rates; run; u.s
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        item: #3670 of 7819
          id: cord-299650-lhphdjeu
      author: Whittle, John
       title: Persistent hypermetabolism and longitudinal energy expenditure in critically ill patients with COVID-19
        date: 2020-09-28
       words: 1159
      flesch: 38
     summary: Further, understanding the energy expenditure of COVID-19 ICU patients is essential to help determine safe, optimal nutrition needs for the ICU provider [3] , as both over-/underfeeding is associated with increased ICU mortality Longitudinal IC data presented here demonstrate a progressive hypermetabolic phenotype beginning 1 week post-intubation in COVID-19 ICU patients, with significantly greater mREE versus predictive equations or ASPEN-recommended 11-14 kcal/kg ABW for obese subjects used currently to determine energy requirements.
    keywords: covid-19; data; icu; mree; patients
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        item: #3671 of 7819
          id: cord-299656-iyb5r7e2
      author: Cioffi, Andrea
       title: La diminution des décès liés à la COVID-19 et le risque de sous-estimer la pandémie
        date: 2020-09-23
       words: 774
      flesch: 52
     summary: Recently, COVID-19 infections are starting to increase again [10] . Therefore, it will be essential to maintain high attention and not underestimate the increases in COVID-19 infections otherwise there is a risk that world governments will become accomplices to damage the health of all citizens.
    keywords: covid-19; health
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        item: #3672 of 7819
          id: cord-299683-nv8kfp7z
      author: Ghosh, Kapil
       title: Inter-state transmission potential and vulnerability of COVID-19 in India
        date: 2020-06-16
       words: 1717
      flesch: 44
     summary: key: cord-299683-nv8kfp7z authors: Ghosh, Kapil; Sengupta, Nairita; Manna, Dipanwita; De, Sunil Kumar title: Inter-state transmission potential and vulnerability of COVID-19 in India date: 2020-06-16 journal: nan DOI: 10.1016/j.pdisas.2020.100114 sha: doc_id: 299683 cord_uid: nv8kfp7z Abstract Since the first case of COVID-19 traced in India on 30th January 2020, the total no. of confirmed cases is amplified. In this context, the fact is noteworthy that every state of India is not equally well-equipped with adequate medical infrastructure to provide necessary health care facilities to the COVID-19 patients.
    keywords: cases; covid-19; health; india; states
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        item: #3673 of 7819
          id: cord-299781-9d5g5xaw
      author: Hrusak, Ondrej
       title: Flash Survey on SARS-CoV-2 Infections in Pediatric Patients on anti-Cancer Treatment
        date: 2020-04-07
       words: 2380
      flesch: 43
     summary: Intensive Care Med SARS-CoV-2 Infection in Children Novel Coronavirus Infection in Hospitalized Infants Under 1 Year of Age in China A Case Series of children with 2019 novel coronavirus infection: clinical and epidemiological features Detection of Covid-19 in Children in Early Epidemiological Characteristics of 2143 Pediatric Patients With 2019 Coronavirus Disease in China Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center's observational study Korean Society for Antimicrobial Therapy, Korean Society for Healthcare-associated Infection Control and Prevention Characteristics and outcomes of coronavirus infection in children: Immunosuppressed children are recommended to be isolated from general pediatric patients, where possible.
    keywords: children; covid-19; disease; infection; patients; sars
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        item: #3674 of 7819
          id: cord-299845-ql3tvot5
      author: Janani, Leila
       title: COVID-19 Population Survey of Iran (COPSIR) study protocol: Repeated survey on knowledge, risk perception, preventive behaviors, psychological problems, essential needs, and public trust during COVID-19 epidemic
        date: 2020-05-25
       words: 1141
      flesch: 49
     summary: Then, 6 experts assessed the content validity of the translated version and modified it for COPSIR study questionnaire. The dimensions of COPSIR study questionnaire and the number of its items are summarized in Table 2 .
    keywords: covid-19; health; study
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        item: #3675 of 7819
          id: cord-299852-t0mqe7yy
      author: Janssen, Loes H. C.
       title: Does the COVID-19 pandemic impact parents’ and adolescents’ well-being? An EMA-study on daily affect and parenting
        date: 2020-10-16
       words: 8586
      flesch: 46
     summary: We tested whether adding parent level (Level 2) to Model 1 for adolescents improved the model fit based on the likelihood ratio tests. Parents and adolescents who agreed to participate were sent an online questionnaire on demographic characteristics and general mental well-being.
    keywords: adolescents; affect; baseline; covid-19; covid-19 pandemic; model; pandemic; parenting; parents
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        item: #3676 of 7819
          id: cord-299869-4yjyqjpe
      author: Wu, J.
       title: Systemic corticosteroids show no benefit in severe and critical COVID-19 patients in Wuhan, China: A retrospective cohort study
        date: 2020-05-14
       words: 2950
      flesch: 42
     summary: For severe COVID-19 patients at admission, corticosteroid use was not associated with improved outcome in either the IPTW analysis. Compared to no corticosteroid use group, systemic corticosteroid use showed no benefit in reducing in-hospital mortality in both severe cases (HR=1.77, 95% CI: 1.08-2.89, p=0.023), and critical cases (HR=2.07, 95% CI: 1.08-3.98, p=0.028).
    keywords: corticosteroids; license; medrxiv; patients; preprint; use
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        item: #3677 of 7819
          id: cord-299882-ee5wathm
      author: Hsiehchen, David
       title: Deficiencies in the designs and interventions of COVID-19 clinical trials
        date: 2020-07-04
       words: 1168
      flesch: 32
     summary: Characteristics of COVID-19 interventional trials Scatter plot of COVID-19 trials and infections (data obtained from the Johns Hopkins COVID-19 dashboard on 5/10/2020) across 60 countries with available data Scatter plot of COVID-19 trials and deaths across 58 countries with available data Number of trials associated with each COVID-19 intervention. These findings indicate that COVID-19 interventional trials have heterogenous designs, but are predominantly open-label, single-center studies regardless of geography.
    keywords: covid-19; interventions; trials
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        item: #3678 of 7819
          id: cord-299888-ig0gy5e9
      author: Ooi, M.W.X.
       title: Pulmonary thromboembolic disease in COVID-19 Patients on CT Pulmonary Angiography –Prevalence, pattern of disease and relationship to D-dimer
        date: 2020-10-06
       words: 1854
      flesch: 49
     summary: To define the prevalence of pulmonary thromboembolic (PTE) disease diagnosed on CT pulmonary angiography (CTPA) in COVID-19 patients. Heparin resistance has also been reported in COVID-19 patients [5] .
    keywords: covid-19; dimer; patients; pte; pulmonary
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        item: #3679 of 7819
          id: cord-299889-x6c3p195
      author: Tirkolaee, Erfan Babaee
       title: Sustainable fuzzy multi-trip location-routing problem for the epidemic outbreak of the novel Coronavirus (COVID-19)
        date: 2020-11-10
       words: 3032
      flesch: 47
     summary: In other words, medical waste disposal is regarded as a significant way to handle the source of infection, strict establishment and standardization of the waste management of COVID-19 (Peng et al. 2020 ). Therefore, in this study, a novel mixed-integer linear programming (MILP) model is developed to formulate the sustainable multi-trip location-routing problem with time windows (MTLRP-TW) for medical waste management in the COVID-19 pandemic.
    keywords: covid-19; disposal; management; model; problem; time; waste
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        item: #3680 of 7819
          id: cord-299899-is815pol
      author: He, Jingjing
       title: Proportion of asymptomatic coronavirus disease 2019 (COVID‐19): a systematic review and meta‐analysis
        date: 2020-07-21
       words: 2581
      flesch: 37
     summary: While a variety of studies on asymptomatic infection have been reported, the proportion of asymptomatic patients in confirmed COVID-19 cases is not well characterized. Asymptomatic COVID‐19 patients could have abnormal laboratory and radiational manifestations which can be used as screening strategies to identify asymptomatic infection.
    keywords: asymptomatic; coronavirus; cov-2; covid-19; infection; patients; sars
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        item: #3681 of 7819
          id: cord-299911-v95pf3eg
      author: El-Ghiaty, Mahmoud A.
       title: Cytochrome P450-mediated drug interactions in COVID-19 patients: current findings and possible mechanisms
        date: 2020-06-26
       words: 5332
      flesch: 31
     summary: IL-1 beta counteracts clofibric acid induction of CYP4A in cultured fetal rat hepatocytes Suppression of CYP2C11 gene transcription by interleukin-1 mediated by NF-kappaB binding at the transcription start site Effects of interleukin 1beta (IL-1beta) and IL-1beta/interleukin 6 (IL-6) combinations on drug metabolizing enzymes in human hepatocyte culture Pretranslational down-regulation of cytochromes P450 2C11 and 3A2 in male rat liver by tumor necrosis factor alpha Nitric oxidemediated inhibition of cytochrome P450 by interferon-gamma in human hepatocytes inactivation by serum from humans with a viral infection and serum from rabbits with a turpentine-induced inflammation: the role of cytokines The interleukin-2 receptor downregulates the expression of cytochrome P450 in cultured rat hepatocytes Decrease in hepatic cytochrome P450 after interleukin-2 immunotherapy In vivo effects of interleukin-10 on human cytochrome P450 activity Down-regulation of the hepatic cytochrome P450 by an acute inflammatory reaction: implication of mediators in human and animal serum and in the liver Cytochrome P450 down-regulation by serum from humans with a viral infection and from rabbits with an inflammatory reaction Effect of interleukin 6 on phenobarbital induction of cytochrome P-450IIB in cultured rat hepatocytes Chauvelot-Moachon L. Effects of interleukin-6 on cytochrome P450-dependent mixed-function oxidases in the rat Interleukin-6 down regulates the expression of transcripts encoding cytochrome P450 IA1, IA2 and IIIA3 in human hepatoma cells Suppression of constitutive cytochrome P-450 gene expression in livers of rats undergoing an acute phase response to endotoxin Selective suppression of cytochrome P-450 gene expression by interleukins 1 and 6 in rat liver Suppression of the constitutive expression of cytochrome P-450 2C11 by cytokines and interferons in primary cultures of rat hepatocytes: comparison with induction of acute-phase genes and demonstration that CYP2C11 promoter sequences are involved in the suppressive response to interleukins 1 and 6 Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent Involvement of interleukin-6 and tumor necrosis factor alpha in CYP3A11 and 2C29 down-regulation by Bacillus Calmette-Guerin and lipopolysaccharide in mouse liver Modulation of hepatic cytochrome P450s by Citrobacter rodentium infection in interleukin-6-and interferon-{gamma}-null mice Cytochrome P450 and antioxidant activity in interleukin-6 knockout mice after induction of the acute-phase response Transgenic mouse models of human CYP3A4 gene regulation Transcriptional repression of hepatic cytochrome P450 3A4 gene in the presence of cancer Downregulation of drug transport and metabolism in mice bearing extra-hepatic malignancies Extrahepatic cancer represses hepatic drug metabolism via interleukin (IL)-6 signalling Effects of cytokines on CYP3A4 expression and reversal of the effects by anti-cytokine agents in the three-dimensionally cultured human hepatoma cell line FLC-4 Effects of interleukin-6 (IL-6) and an anti-IL-6 monoclonal antibody on drug-metabolizing enzymes in human hepatocyte culture Gene transcription in hepatocytes during the acute phase of a systemic inflammation: from transcription factors to target genes Regulation of cytochrome p450 by inflammatory mediators: why and how? NF-kappaB and the immune response Role of NF-kappaB in the regulation of cytochrome P450 enzymes Mechanism of suppression of cytochrome P-450 1A1 expression by tumor necrosis factor-alpha and lipopolysaccharide Ah receptor and NF-kappaB interactions: mechanisms and physiological implications Modulation of CYP1A2 and CYP3A6 catalytic activities by serum from rabbits with a turpentine-induced inflammatory reaction and interleukin 6 Inhibition of nuclear factor-kappaB signal by pyrrolidine dithiocarbamate alleviates lipopolysaccharide-induced acute lung injury Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents Pregnane X receptor is required for interleukin-6-mediated down-regulation of cytochrome P450 3A4 in human hepatocytes Is nuclear factor kappa-B the missing link between inflammation, cancer and alteration in hepatic drug metabolism in patients with cancer? = Zhonghua ganzangbing zazhi = Chinese journal of hepatology Specific ACE2 Expression in Cholangiocytes May Cause Liver Damage After 2019-nCoV Infection Liver injury in COVID-19: management and challenges COVID-19 and Liver Dysfunction: Current Insights and Emergent Therapeutic Strategies COVID-19 and liver disease Systemic viral infections and collateral damage in the liver Kupffer cell-dependent hepatitis occurs during influenza infection Liver involvement during influenza infection: perspective on the 2009 influenza pandemic Complex Drug-Drug Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives Trends in new drug interactions for pharmaceutical products in Japan Infection and inflammation leading to clozapine toxicity and intensive care: a case series Decreased dromotropic response to verapamil despite pronounced increased drug concentration in rheumatoid arthritis Influence of chronic hepatitis C infection on cytochrome P450 3A4 activity using midazolam as an in vivo probe substrate Drug-disease interaction: Crohn's disease elevates verapamil plasma concentrations but reduces response to the drug proportional to disease activity Variability in drug metabolizing enzyme activity in HIV-infected patients Altered theophylline clearance during an influenza B outbreak The use of imipramine in depressed patients with congestive heart failure Understanding Disease-Drug Interactions in Cancer Patients: Implications for Dosing Within the Therapeutic Window Disease-drug-drug interaction involving tocilizumab and simvastatin in patients with rheumatoid arthritis Disease-Drug Interaction of Sarilumab and Simvastatin in Patients with Rheumatoid Arthritis Evaluation of disease-mediated therapeutic protein-drug interactions between an anti-lnterleukin-6 monoclonal antibody (Sirukumab) and cytochrome P450 activities in a phase I study in patients with rheumatoid arthritis using a cocktail approach A physiologically based pharmacokinetic modeling approach to predict disease-drug interactions: suppression of CYP3A by IL-6 Development of a Physiologically Based Pharmacokinetic Model to Predict Disease-Mediated Therapeutic Protein-Drug Interactions: Modulation of Multiple Cytochrome Physiologically Based Pharmacokinetic Model to Assess the Influence of Blinatumomab-Mediated Cytokine Elevations on Cytochrome P450 Enzyme Activity Summary on compassionate use of Remdesivir Gilead Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies The Greek study in the effects of colchicine in COvid-19 complications prevention (GRECCO-19 study): Rationale and study design In vitro metabolism of chloroquine: identification of CYP2C8, CYP3A4, and CYP2D6 as the main isoforms catalyzing Ndesethylchloroquine formation Colchicine--Update on mechanisms of action and therapeutic uses Critical Care Utilization for the COVID-19 Early Experience and Forecast During an Emergency Response Forecasting COVID-19 impact on hospital bed-days, ICU-days, ventilator-days and deaths by US state in the next 4 months Drug-associated disease: cytochrome P450 interactions Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region Clinical implications from drug-drug and drug-disease interactions in older people An update on the clinical consequences of polypharmacy in older adults: a narrative review
    keywords: activity; covid-19; cyps; cytochrome; disease; drug; expression; hepatic; il-6; liver; p450; patients; response
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        item: #3682 of 7819
          id: cord-299927-ixuvy2g4
      author: Frontera, Jennifer
       title: Global Consortium Study of Neurological Dysfunction in COVID-19 (GCS-NeuroCOVID): Study Design and Rationale
        date: 2020-05-22
       words: 4866
      flesch: 26
     summary: A rapid and pragmatic approach to understanding the prevalence, phenotypes, pathophysiology and prognostic implications of COVID-19 neurological syndromes is urgently needed. CDE development for COVID-19 neurological dysfunction will follow the guidelines set forth by the NINDS CDE project [36, 37, [40]
    keywords: acute; cov-2; covid-19; data; dysfunction; infection; patients; prevalence; sars; study; syndrome; tier
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        item: #3683 of 7819
          id: cord-299932-c079r94n
      author: He, X.
       title: Benchmarking Deep Learning Models and Automated Model Design for COVID-19 Detection with Chest CT Scans
        date: 2020-06-09
       words: 6210
      flesch: 58
     summary: Our experimental results show that DL models are promising solutions, and 3D models outperform 2D models. The models are trained with the training set and evaluated on the test set. 1) Exp 1: Comparing different CNN models: In this study, we evaluate 17 CNN classification models shown in Table III , including 3D models and 2D models.
    keywords: covid-19; dataset; images; models; number; performance; scan; slices
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        item: #3684 of 7819
          id: cord-299999-jra1yu6a
      author: Tattar, R.
       title: COVID PDPs
        date: 2020-05-22
       words: 1631
      flesch: 41
     summary: The bearing COVID-19 has had on clinical activity means that many patients being treated and prepared for cases will be delayed, target case numbers and important clinical exposure will reduce, negatively impacting trainees' progression. Furthermore, many patients who undergo resection of oral cancer require post-operative intensive treatment unit (ITU) beds.
    keywords: cancer; covid-19; dental; pandemic; patients; training
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        item: #3685 of 7819
          id: cord-300013-6m1f4q5r
      author: Brahier, Thomas
       title: Lung ultrasonography for risk stratification in patients with COVID-19: a prospective observational cohort study
        date: 2020-09-17
       words: 3250
      flesch: 45
     summary: Systematic LUS has potential as a reliable, cheap and easy-to-use triage tool for the early risk stratification in COVID-19 patients presenting in EDs The Coronavirus disease pandemic has overwhelmed the health systems in several high-income settings (1) , and is now spreading in the low-income countries. While the majority of COVID-19 patients have a paucisymptomatic or asymptomatic course, some may rapidly deteriorate leading to hospitalisation and the need for respiratory support.
    keywords: covid-19; lung; lus; patients; score; severity; study
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        item: #3686 of 7819
          id: cord-300030-s4i0mdqe
      author: Jaguga, Florence
       title: Mental health response to the COVID-19 pandemic in Kenya: a review
        date: 2020-08-18
       words: 3477
      flesch: 45
     summary: key: cord-300030-s4i0mdqe authors: Jaguga, Florence; Kwobah, Edith title: Mental health response to the COVID-19 pandemic in Kenya: a review date: 2020-08-18 journal: Int J Ment Health Syst DOI: 10.1186/s13033-020-00400-8 sha: doc_id: 300030 cord_uid: s4i0mdqe BACKGROUND: 'Monitoring and assessment' requires the development of a mental health surveillance system to enable continuous collection of data on mental health for at risk populations as well as the general population.
    keywords: care; covid-19; health; kenya; pandemic; plan; response
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        item: #3687 of 7819
          id: cord-300032-511zwrnb
      author: van Steveninck, Alfred L.
       title: Diaphragm dysfunction prior to intubation in a patient with Covid-19 pneumonia; assessment by point of care ultrasound and potential implications for patient monitoring
        date: 2020-11-10
       words: 1662
      flesch: 38
     summary: Future studies of diaphragm function in patients with severe pneumonia may help to improve the timing of a switch to mechanical ventilation as well as strategies for monitoring and treatment in ventilated patients. The clinical research described in this case report was initiated because of the recognized need for early identification of Covid-19 patients at risk of respiratory failure.
    keywords: diaphragm; patient; respiratory; ventilation
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        item: #3688 of 7819
          id: cord-300037-gtfx5cp4
      author: Hsiang, Solomon
       title: The Effect of Large-Scale Anti-Contagion Policies on the Coronavirus (COVID-19) Pandemic
        date: 2020-03-27
       words: 14710
      flesch: 53
     summary: We relied on news media reporting and two timelines of pandemic events in Iran 5 6 to collate policy data. In some cases (for Italy and the US), policy data is available at a more spatially granular level than infection data (e.g. city policies and state-level infections in the US).
    keywords: cases; country; covid-19; data; day; growth; health; infections; level; license; march; number; policies; policy; preprint; rate; version
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        item: #3689 of 7819
          id: cord-300038-1fjb6b8e
      author: Cantini, Fabrizio
       title: Baricitinib therapy in COVID-19: A pilot study on safety and clinical impact
        date: 2020-04-23
       words: 1264
      flesch: 41
     summary: On this basis, we assessed the safety of baricitinib therapy combined with lopinavir-ritonavir in moderate COVID-19 pneumonia patients and we evaluated its clinical impact. These results were likely due to the rapid action of the drug and the short median interval of 6 days from symptoms-onset and therapy starting, The major limitations of this pilot study were its open-label design with no randomization and the low number of treated patients.
    keywords: baricitinib; covid-19; patients; therapy; treatment
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        item: #3690 of 7819
          id: cord-300039-h7pk9mh8
      author: Ho, Jamie S. Y.
       title: A Call for Vaccine Against COVID-19: Implications for Cardiovascular Morbidity and Healthcare Utilization
        date: 2020-05-08
       words: 1019
      flesch: 37
     summary: Patients with cardiovascular diseases such as ischemic heart disease and hypertension have an increased risk of severe disease and death. Due to the possible cardiovascular benefits and low risk of harm, influenza vaccination is still recommended by international guidelines in the prevention of cardiovascular disease in the elderly population and secondary prevention setting.
    keywords: cardiovascular; covid-19; influenza; patients
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        item: #3691 of 7819
          id: cord-300046-orlga9qf
      author: Gomes da Silva, J.
       title: Health literacy of inland population in the mitigation phase 3.2. of COVID-19's pandemic in Portugal - a descriptive cohort study
        date: 2020-05-14
       words: 5402
      flesch: 42
     summary: Disease outbreak news Novel Coronavirus (COVID-19) Outbreak: A Review of the Current Literature The reproductive number of COVID-19 is higher compared to SARS coronavirus Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical features of patients infected with 2019 novel coronavirus in Wuhan A novel coronavirus from patients with pneumonia in China Identification of severe acute respiratory syndrome in Canada Clinical characteristics of coronavirus disease 2019 in China Post-pandemic Assessment of Public Knowledge, Behavior, and Skill on Influenza Prevention Among the General Population of Beijing, China A cross-sectional study of pandemic influenza health literacy and the effect of a public health campaign Diagnóstico e Plano Municipal para a Igualdade Health literacy in Europe: comparative results of the European health literacy survey (HLS-EU) How Often Do You Wash Your Hands? A Tale of Two Epidemics Communication of scientific uncertainty about a novel pandemic health threat: ambiguity aversion and its mechanisms A cross-sectional study of pandemic influenza health literacy and the effect of a public health campaign Community Matters -why outbreak responses need to integrate health promotion Fair Allocation of Scarce Medical Resources in the Time of Covid-19 How will country-based mitigation measures influence the course of the COVID-19 epidemic?
    keywords: covid-19; group; health; individuals; license; literacy; preprint; risk; study
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        item: #3692 of 7819
          id: cord-300078-svu06v9c
      author: Haghani, Milad
       title: Covid-19 pandemic and the unprecedented mobilisation of scholarly efforts prompted by a health crisis: Scientometric comparisons across SARS, MERS and 2019-nCov literature
        date: 2020-06-01
       words: 6373
      flesch: 43
     summary: Covid-19 studies seem to have been distributed across a broader variety of journals and subject areas. Covid-19 studies also display the involvement of authors from a broader variety of countries compared to SARS and MRS.
    keywords: cluster; covid-19; items; literature; mers; number; research; sars; studies; terms
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        item: #3693 of 7819
          id: cord-300094-xynwf38q
      author: Drak Alsibai, Kinan
       title: Detection of Hemosiderin-Laden Macrophages in Bronchoalveolar Lavage Fluid of COVID-19 Patients: Is Perls Stain a Potential Indicator of Oxidative Alveolar Damage?
        date: 2020-06-05
       words: 1614
      flesch: 40
     summary: Consequently, the pulmonary lesions described on chest computed tomography scan are thought to be the result of the inability to exchange carbon dioxide and oxygen and the release of oxidative iron from the hemes, which overwhelm the natural defenses against pulmonary oxidative stress and may eventually result in bilateral ground-glass-like opacities in COVID-19 patients. It is evident that confirmation of the utility of Golde score using Perls stain or immunocytochemical technique to detect ferric iron as an indicator of pulmonary damage in COVID-19 patients requires validation by a series of cytological examination of BAL, while taking the necessary technical precautions as fresh BAL of COV-ID-19 patients is considered a high-risk infectious fluid for the laboratory team.
    keywords: covid-19; iron; oxygen; patients; perls
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        item: #3694 of 7819
          id: cord-300132-lbbibqv3
      author: Clifford, Christopher T.
       title: Association between COVID-19 diagnosis and presenting chief complaint from New York City triage data
        date: 2020-11-07
       words: 2833
      flesch: 51
     summary: A novel high risk COVID-19 patient population was identified from chief complaint data, which is different from current suggested CDC guidelines, and may help triage systems to better isolate COVID-19 patients. Conclusion: A novel high risk COVID-19 patient population was identified from chief complaint data, which is different from current suggested CDC guidelines, and may help triage systems to better isolate COVID-19 patients.
    keywords: chief; complaints; covid-19; data; patients; triage
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        item: #3695 of 7819
          id: cord-300163-06hbegx1
      author: Harris, Jody
       title: Food system disruption: initial livelihood and dietary effects of COVID-19 on vegetable producers in India
        date: 2020-07-14
       words: 5352
      flesch: 48
     summary: key: cord-300163-06hbegx1 authors: Harris, Jody; Depenbusch, Lutz; Pal, Arshad Ahmad; Nair, Ramakrishnan Madhavan; Ramasamy, Srinivasan title: Food system disruption: initial livelihood and dietary effects of COVID-19 on vegetable producers in India date: 2020-07-14 journal: Food Secur DOI: 10.1007/s12571-020-01064-5 sha: doc_id: 300163 cord_uid: 06hbegx1 Disruption to food systems and impacts on livelihoods and diets have been brought into sharp focus by the COVID-19 pandemic. Importantly, different foods are likely to be affected differently by food system shocks.
    keywords: covid-19; diets; farmers; farms; food; households; india; prices; production; sales; vegetables
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        item: #3696 of 7819
          id: cord-300167-5vxo6wqt
      author: Mi, Bobin
       title: Serum Mycoplasma Pneumoniae IgG in COVID-19: A Protective Factor
        date: 2020-04-17
       words: 715
      flesch: 35
     summary: Continuous variables were described as mean, median, and interquartile range (IQR), while categorical variables were compared by X2 test or Fisher's exact test between COVID-19 infected patients with mycoplasma lgG (-) and mycoplasma lgG (+). COVID-19 infected patients with mycoplasma lgG positivity had a higher lymphocyte count and percentage (p=0.026, p=0.017), monocyte count and percentage (p=0.028, p=0.006) and eosinophil count and percentage (p=0.039, p=0.007), and a lower neutrophil count and percentage (p=0.044, p=0.006) than COVID-19 infected patients without mycoplasma lgG. Other routine blood tests, including coagulation tests, blood biochemistry and infection-related biomarkers did not significantly differ except for thrombin time (p=0.001) and lactate dehydrogenase (p=0.008).
    keywords: covid-19; mycoplasma; patients
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        item: #3697 of 7819
          id: cord-300183-z3fwtwqb
      author: Ahmed, Taha
       title: Community and healthcare system-related factors feeding the phenomenon of evading medical attention for time-dependent emergencies during COVID-19 crisis
        date: 2020-08-25
       words: 3449
      flesch: 44
     summary: The data from various countries of Europe show a 25%-40% drop in STEMI presentations and admissions as compared with during the peak of pandemic. [8] [9] [10] In the USA, a comparable decrease in STEMI presentations is reported in different states irrespective of the state's burden of COVID-19.
    keywords: care; complications; covid-19; healthcare; infarction; pandemic; patient; presentation; stemi
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        item: #3698 of 7819
          id: cord-300192-fgueg4mo
      author: Richardson, David P.
       title: Nutritional status of micronutrients as a possible and modifiable risk factor for COVID-19: a UK perspective
        date: 2020-08-20
       words: 5750
      flesch: 26
     summary: The vitamin D deficiency pandemic: approaches for diagnosis, treatment and prevention Vitamin D deficiency: defining, prevalence, causes and strategies of addressing Contribution of nutrition science to the vitamin D field -clarity or confusion? Vitamin D deficiency 2.0: an update on the current status worldwide SACN vitamin D and health report Vitamin D levels and deficiency with different occupations: a systematic review Review: non-musculoskeletal benefits of vitamin D Editorial: low population mortality from COVID-19 in countries south of latitude 35 degrees North supports vitamin D as a factor determining severity Evaluation of vitamin D 3 intakes up to 15,000 international units/day and serum 25-hydroxyvitamin D concentrations up to 300 nmol/L on calcium metabolism in a community setting Controversies in vitamin D: summary statement from an international conference Dietary supplement use at the population level: recent experience from the 1994-5 British National Diet and Nutrition Survey: people aged 65 and over Hospital mealtimes: action research for change? Incidence and recognition of malnutrition in hospital Nutritional issues in nursing home care Protein energy undernutrition in hospital patients Trace mineral intake and deficiencies in older adults living in the community and institutions: a systematic review Age-related smell and taste impairment and vitamin D associations in the U.S. Adults National Health and Nutrition Examination Survey Vitamin D in renal transplantation -from biological mechanism to clinical benefits Current evidence on vitamin D deficiency and kidney transplant: what's new? Food and Nutrition Board & Institute of Medicine (1997) It has also been shown that there is a linear association between vitamin D status and respiratory infections and lung function (33) .
    keywords: covid-19; deficiency; health; infections; intakes; nutrition; risk; status; system; vitamin
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        item: #3699 of 7819
          id: cord-300200-vcclz0bu
      author: Ahmed, Sibtain
       title: Trend analysis of lab tests requisitions of COVID-19 prognostic biomarkers at a clinical chemistry reference laboratory-an observational study
        date: 2020-11-06
       words: 3056
      flesch: 43
     summary: The aim of this study was to investigate the trend in COVID-19 prognostic biomarkers requisitions including C-RP, PCT, LDH and Ferritin, at a high-volume clinical chemistry laboratory in Pakistan during the peak pandemic months. key: cord-300200-vcclz0bu authors: Ahmed, Sibtain; Ghani, Farooq title: Trend analysis of lab tests requisitions of COVID-19 prognostic biomarkers at a clinical chemistry reference laboratory-an observational study date: 2020-11-06 journal:
    keywords: biomarkers; covid-19; laboratory; patients; prognostic; study; test
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        item: #3700 of 7819
          id: cord-300222-kzzx8ni7
      author: Mellan, T. A.
       title: Report 21: Estimating COVID-19 cases and reproduction number in Brazil
        date: 2020-05-18
       words: 4484
      flesch: 46
     summary: We additionally consider the possibility that the extent of COVID-19 death underreporting has been non-stationary over time -specifically, that increases in the ascertainment of COVID-19 deaths over time during the initial phase of the epidemic could lead to upwards biasing of our R 0 estimates. Estimates of the expected IFR across different states are derived from previously published estimates of mixing patterns in a Latin America setting [3] alongside estimates of the virus' transmissibility (the basic reproduction number, R 0 ) derived from European settings [7] and from estimates of disease sever-DOI:
    keywords: covid-19; deaths; license; mobility; number; preprint; results; states
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        item: #3701 of 7819
          id: cord-300229-9qh7efs4
      author: Inchausti, Felix
       title: Psychological Intervention and COVID-19: What We Know So Far and What We Can Do
        date: 2020-05-27
       words: 5193
      flesch: 32
     summary: Psychotherapy relationships that workevidence-based therapist contributions Do no harm: Balancing the costs and benefits of patient outcomes in health psychology research and practice Negotiating the therapeutic alliance: A relational treatment guide The 2014 Ebola outbreak and mental health: Current status and recommended response Trauma signature analysis Impact of economic crises on mental health care: A systematic review The psychology of pandemics. The coronavirus COVID-19 and the global pandemic has already had a substantial disruptive impact on society, posing major challenges to the provision of mental health services in a time of crisis, and carrying the spectre of an increased burden to mental health, both in terms of existing psychiatric disorder, and emerging psychological distress from the pandemic.
    keywords: covid-19; crisis; health; interventions; pandemic; patients; professionals; psychological; risk; self; treatment
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        item: #3702 of 7819
          id: cord-300236-mon1loph
      author: Williams, Bryan
       title: Hypertension, renin–angiotensin–aldosterone system inhibition, and COVID-19
        date: 2020-05-14
       words: 1241
      flesch: 28
     summary: Nor does evidence exist to suggest that, once infected, the risk of admission to hospital due to COVID-19, progression to more severe complications, or death is increased with RAAS inhibitor use compared with treatment with other antihypertensive drugs. These factors have fuelled speculation that use of RAAS inhibitors, particularly ACE inhibitors or angiotensin-receptor blockers, could lead to increased expression of ACE2 in the respiratory tract, thereby increasing the risk of both becoming infected and developing severe life-threatening complications due to COVID-19.
    keywords: covid-19; inhibitors; risk
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        item: #3703 of 7819
          id: cord-300240-mie5yxj4
      author: Cañizares Fuentes, Ricardo
       title: Evaluation of COVID-19 Surveillance Strategy in Ecuador
        date: 2020-09-09
       words: 1534
      flesch: 43
     summary: With this in mind, the possibility of occurrence obtained in Ecuador, based on the second principle (selectivity), was compared-thanks to the reports issued periodically by the Ecuadorian Ministry of Public Health on COVID-19 positive cases-with the cases of South Korea and Iceland, based on the first principle (randomness), until April 13, 2020. In addition, the Ecuadorian public health network had insufficient COVID-19 tests, a condition that is measured as sufficient tests applied for each hundred thousand or million inhabitants and that allows determining the effectiveness and efficiency of the actions of public entities.
    keywords: cases; covid-19; symptomatic; tests
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        item: #3704 of 7819
          id: cord-300246-fxqseibh
      author: Badyal, Dinesh Kumar
       title: Chloroquine: Can it be a Novel Drug for COVID-19
        date: 2020-04-02
       words: 1409
      flesch: 49
     summary: naming-the-coron avirus-disease-(covid-2019)-and-the-virus-that-causes-it Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies World Health Organization (WHO). Chloroquine and phosphate hydroxychloroquine are the drugs currently in the limelight, and recently, the National Task Force for COVID-19 constituted by the Indian Council of Medical Research has recommended the use of antimalarial drug hydroxychloroquine for prophylaxis of severe acute respiratory syndrome-coronavirus 2 infection in selected high-risk individuals.
    keywords: chloroquine; covid-19; drug; health
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        item: #3705 of 7819
          id: cord-300297-csacrppf
      author: Pinggera, Daniel
       title: The influence of the COVID-19 pandemic on traumatic brain injuries in Tyrol: experiences from a state under lockdown
        date: 2020-07-22
       words: 2628
      flesch: 45
     summary: Neurosurgery Severe traumatic brain injury is associated with a unique coagulopathy phenotype COVID-19 and its implications for thrombosis and anticoagulation Effects of hospital-acquired pneumonia on long-term recovery and hospital resource utilization following moderate to severe traumatic brain injury Incidence of post-traumatic pneumonia in poly-traumatized patients: identifying the role of traumatic brain injury and chest trauma Timing of tracheostomy placement among children with severe traumatic brain injury: a propensity-matched analysis High population densities catalyze the spread of COVID-19 Impact of prehospital transportation on survival in skiers and snowboarders with traumatic brain injury Increased mortality associated with cerebral contusions following trauma in the elderly: bad patients or bad management? key: cord-300297-csacrppf authors: Pinggera, Daniel; Klein, Barbara; Thomé, Claudius; Grassner, Lukas title: The influence of the COVID-19 pandemic on traumatic brain injuries in Tyrol: experiences from a state under lockdown date: 2020-07-22 journal:
    keywords: brain; covid-19; injury; patients; quarantine; tbi; tyrol
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        item: #3706 of 7819
          id: cord-300300-jqi4ylrx
      author: Lin, Ray Junhao
       title: From SARS to COVID‐19: the Singapore journey
        date: 2020-05-31
       words: 2614
      flesch: 43
     summary: 2 Professional personnel and training of health care workers in outbreak response were expanded, with the number of infectious disease physicians rising from 11 in 2003 to 73 in 2020. Since the transmission of SARS-CoV-2 to health care workers was reported on 20 January 2020, 23 twicedaily temperature monitoring was mandated for all frontline health care workers in all public hospitals.
    keywords: care; cases; covid-19; health; patients; public; singapore
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        item: #3707 of 7819
          id: cord-300303-d4qmtysd
      author: de Azambuja, Evandro
       title: ESMO Management and treatment adapted recommendations in the COVID-19 era: Breast Cancer
        date: 2020-05-20
       words: 6990
      flesch: 25
     summary: CC declares consultancy/advisory role/speaker's bureau: Pfizer Cancer guidelines during the COVID-19 pandemic Fair allocation of scarce medical resources in the time of Covid-19 Impact of nonpharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand Essential care of critical illness must not be forgotten in the COVID-19 pandemic Measuring performance on the healthcare access and quality index for 195 countries and territories and selected subnational locations: a systematic analysis from the global burden of disease study 2016 Cancer, COVID-19 and the precautionary principle: prioritizing treatment during a global pandemic Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China COVID-19: operational guidance for maintaining essential health services during an outbreak interim guidance Identify priority problems and goals to improve the model of care ESMO-Magnitude of clinical benefit scale version 1.1 Contributing to a global effort Effects of multidisciplinary team working on breast cancer survival: retrospective, comparative, interventional cohort study of 13 722 women Influence of neutropenia on mortality of critically ill cancer patients: results of a meta-analysis on individual data The financial burden and distress of patients with cancer: understanding and stepping-up action on the financial toxicity of cancer treatment Delay in breast cancer: implications for stage at diagnosis and survival Prognosis after ipsilateral breast tumor recurrence and locoregional recurrences in patients treated by breast-conserving therapy in five national surgical adjuvant breast and bowel project protocols of node-negative breast cancer Adjuvant therapy after excision and radiation of isolated postmastectomy locoregional breast cancer recurrence: definitive results of a phase III randomized trial (SAKK 23/82) comparing tamoxifen with observation Efficacy of chemotherapy for ER-negative and ER-positive isolated locoregional recurrence of breast cancer: final analysis of the CALOR trial Management of cardiac disease in cancer patients throughout oncological treatment: ESMO consensus recommendations Risk score for drugassociated QTc prolongation. While the score has been applied to a several novel compounds for breast cancer treatment, mostly in the advanced setting, less scoring has been performed in the early breast cancer setting, particularly with chemotherapy regimens, and this should be considered when balancing risk and benefits.
    keywords: breast; breast cancer; cancer; care; clinical; covid-19; health; healthcare; interventions; oncology; pandemic; patients; priority; setting; treatment
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        item: #3708 of 7819
          id: cord-300310-21llzfxz
      author: Kilham, Henry A
       title: COVID‐19 apocalypse for children: Predictable, preventable?
        date: 2020-08-24
       words: 698
      flesch: 65
     summary: This commentary, then, is restricted to considering children and young people, and essentially argues that these age groups can reasonably be predicted to face an apocalypse from the downstream economic effects of the pandemic. First, although, is the joyous fact that it is very rare for children and young people to suffer severe disease and die from COVID-19.
    keywords: children; people
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        item: #3709 of 7819
          id: cord-300320-07tdrd4w
      author: Siordia, Juan A.
       title: Systematic and Statistical Review of Coronavirus Disease 19 Treatment Trials
        date: 2020-07-15
       words: 4849
      flesch: 42
     summary: key: cord-300320-07tdrd4w authors: Siordia, Juan A.; Bernaba, Michael; Yoshino, Kenji; Ulhaque, Abid; Kumar, Sooraj; Bernaba, Mario; Bergin, Edward title: Systematic and Statistical Review of Coronavirus Disease 19 Treatment Trials date: 2020-07-15 journal: SN Compr Clin Med DOI: 10.1007/s42399-020-00399-6 sha: doc_id: 300320 cord_uid: 07tdrd4w The following systematic review and meta-analysis compile the current data regarding human controlled COVID-19 treatment trials. The following systematic and statistical review assesses the current evidence regarding human controlled COVID-19 treatment trials.
    keywords: arbidol; covid-19; effects; favipiravir; heparin; hydroxychloroquine; lopinavir; patients; ritonavir; studies; treatment
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        item: #3710 of 7819
          id: cord-300324-95fty9yi
      author: Ni Lochlainn, M.
       title: Key predictors of attending hospital with COVID19: An association study from the COVID Symptom Tracker App in 2,618,948 individuals
        date: 2020-04-29
       words: 4273
      flesch: 43
     summary: It is possible that, in contrast to the diagnosis of diabetes, there was substantial underdiagnosis or poor recognition of pulmonary disease in patients with COVID-19 patients described in early Chinese cohort studies. In addition, it is becoming apparent that COVID-19 can cause acute kidney injury (AKI) in COVID-19, and this confers a worse prognosis: a Chinese prospective cohort study (n=701) reported that 44% and 27% of COVID-19 patients had proteinuria and haematuria on admission, respectively, with 5.1% of this cohort developed AKI during their hospital stay (38) .
    keywords: app; covid-19; disease; hospital; infection; patients; preprint; risk; symptoms
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        item: #3711 of 7819
          id: cord-300325-f3eomugb
      author: Ferguson, Nadia C.
       title: Clinical Pharmacists: An Invaluable Part of the Coronavirus Disease 2019 Frontline Response
        date: 2020-10-15
       words: 2475
      flesch: 25
     summary: key: cord-300325-f3eomugb authors: Ferguson, Nadia C.; Quinn, Nicholas J.; Khalique, Saira; Sinnett, Mark; Eisen, Lewis; Goriacko, Pavel title: Clinical Pharmacists: While literature reports on the experiences of many frontline staff, there is a scarcity of reports on the role of clinical pharmacists during this crisis.
    keywords: care; coronavirus; covid-19; drug; medication; pandemic; patients; pharmacists; use
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        item: #3712 of 7819
          id: cord-300338-duhyb754
      author: Urashima, Mitsuyoshi
       title: BCG Vaccination and Mortality of COVID-19 across 173 Countries: An Ecological Study
        date: 2020-08-03
       words: 5682
      flesch: 39
     summary: An ecological study was conducted by obtaining data of 61 factors in 173 countries, including BCG vaccine coverage (%), using morbidity and mortality as outcomes, obtained from open resources. Only countries that had data of both total deaths and BCG vaccine coverage were included for analyses in this study.
    keywords: bcg; countries; covid-19; morbidity; mortality; pcr; population; tests; vaccine
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        item: #3713 of 7819
          id: cord-300360-h6gr91eg
      author: Górski, Andrzej
       title: Phages in the fight against COVID-19?
        date: 2020-08-26
       words: 2935
      flesch: 35
     summary: The present antibiotic crisis has greatly ignited interest in the potential of phages in treating multidrug-resistant bacterial infections with the aid of phage therapy. On the other hand, recent progress in our understanding of phage immunobiology opens perspectives for the repurposing of phage therapy to clinical indications other than bacterial infections alone.
    keywords: cells; covid-19; human; infections; phage; therapy; treatment
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        item: #3714 of 7819
          id: cord-300369-q66xifmu
      author: Oyeniran, Oluwatosin I.
       title: Lutte contre la pandémie de maladie à coronavirus (Covid-19): tirer les leçons de la réponse à la maladie du virus Ebola
        date: 2020-07-03
       words: 1744
      flesch: 49
     summary: The spread of awareness and its impact on epidemic outbreaks Modeling the role of public health education in Ebola virus disease outbreaks in Sudan The communication aspects of the Ebola virus disease outbreak in Western Africa-do we need to counter one, two, or many epidemics Preparation and response to the 2014 Ebola virus disease epidemic in Nigeria-the experience of a tertiary hospital in Nigeria Health care workers indicate ill preparedness for Ebola Virus Disease outbreak in Ashanti Region of Ghana Strengthening healthcare workforce capacity during and post Ebola outbreaks in Liberia: an innovative and effective approach to epidemic preparedness and response The role of the polio program infrastructure in response to Ebola virus disease outbreak in Nigeria A practical communitybased response strategy to interrupt Ebola transmission in Sierra Leone Social mobilization and community engagement central to the Ebola response in West Africa: Human health versus human rights: An emerging ethical dilemma arising from coronavirus disease pandemic Looming threat of COVID-19 infection in Africa: act collectively, and fast Novel Coronavirus disease 2019 (COVID-19) outbreak in Nigeria: how effective are government interventions Preparing the Next Generation of African Healthcare Workers and Scientists: Lessons from Coronavirus Pandemic Countries rush to build diagnostic capacity as coronavirus spreads Scientists fear coronavirus spread in countries least able to contain it Ebola virus disease outbreak-Nigeria What was the effect of the West African Ebola outbreak on health programme performance, and did programmes recover? World Health Organization (WHO) INT.
    keywords: coronavirus; covid-19; disease; ebola
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        item: #3715 of 7819
          id: cord-300378-m7p3d3k1
      author: Tiirinki, Hanna
       title: COVID-19 pandemic in Finland – preliminary analysis on health system response and economic consequences
        date: 2020-08-27
       words: 7876
      flesch: 49
     summary: The municipalities can organize health care for their residents themselves or the service can be organized in collaboration with another municipality or a joint municipal authority. 61/2020 Far-reaching impacts of the COVID-19 epidemic on people's well-being and social and health care services Effects of COVID-19 epidemic on the population's service needs, the service system and the economy -rapid impact assessment.
    keywords: care; covid-19; districts; epidemic; finland; finnish; government; health; hospital; measures; municipalities; number; pandemic; patients; public; system
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        item: #3716 of 7819
          id: cord-300396-kea01a27
      author: Sharpe, Richard E
       title: Special Report of the RSNA COVID-19 Task Force: The Short- and Long-Term Financial Impact of the COVID-19 Pandemic on Private Radiology Practices
        date: 2020-07-17
       words: 3543
      flesch: 39
     summary: The report synthesizes publicly available data with the collective experience of private practice radiologists informally shared with members of the Radiological Society of North America (RSNA) COVID-19 Task Force, including discussions with colleagues and leaders of private radiology practices from across the United States. This report synthesizes the collective experience of private practice radiologists shared with members of the Radiological Society of North America (RSNA) COVID-19 Task Force, including discussions with colleagues and leaders of private practice radiology groups from across the United States.
    keywords: covid-19; imaging; impact; pandemic; practices; radiologists; radiology; services; term; time
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        item: #3717 of 7819
          id: cord-300399-21xozruq
      author: Jayamohan, Harikrishnan
       title: SARS-CoV-2 pandemic: a review of molecular diagnostic tools including sample collection and commercial response with associated advantages and limitations
        date: 2020-10-18
       words: 13021
      flesch: 38
     summary: Recent studies on four different commercial antigen tests demonstrated a wide range of sensitivities from 16.7 to 85% (with 100% specificity) in COVID-19 clinical samples [113] . Such methods have been extensively reviewed [44, 163, 164] and will need to be validated with COVID-19 clinical samples.
    keywords: amplification; antibody; antigen; assay; collection; coronavirus; cov-2; covid-19; crispr; detection; diagnostic; novel; pandemic; patients; pcr; rna; samples; sars; sensitivity; sequencing; swabs; testing; tests
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        item: #3718 of 7819
          id: cord-300439-d86p43u1
      author: Bello, Ajide Kazeem
       title: Estimating the impacts of lockdown on Covid-19 cases in Nigeria
        date: 2020-09-06
       words: 2219
      flesch: 48
     summary: ONLINE FORECASTING OF COVID-19 CASES IN NIGERIA USING LIMITED DATA Does Democracy Really Fuel Terrorism in Africa? Natural resource rents, political regimes, and terrorism in Africa Public health implication of displacement of Almajiri children in specific states of Northern Nigeria amidst COVID-19 pandemic Burden of Middle East respiratory syndrome coronavirus infection in Saudi Arabia Modeling Nigerian Covid-19 cases: A comparative analysis of models and estimators A spatio-temporal analysis for exploring the effect of temperature on COVID-19 early evolution in Spain Indirect virus transmission in cluster of COVID-19 cases Wuhan lockdown unprecedented, shows commitment to contain virus: WHO representative in China Estimation of COVID-19 prevalence in Italy, Spain, and France. Against the foregoing backdrop, this study seeks to examine the impact of lockdown on COVID-19 cases in Nigeria.
    keywords: covid-19; lockdown
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        item: #3719 of 7819
          id: cord-300445-qzu4gz2d
      author: Zhang, Xiao-lei
       title: Pharmacological and cardiovascular perspectives on the treatment of COVID-19 with chloroquine derivatives
        date: 2020-09-23
       words: 7259
      flesch: 34
     summary: Chloroquine phosphate and its derivative hydroxychloroquine, which have been used in the treatment and prevention of malaria and autoimmune diseases for decades, were found to inhibit SARS-CoV-2 infection with high potency in vitro and have shown clinical and virologic benefits in COVID-19 patients. Later, under a limited emergency-use authorization from the FDA, hydroxychloroquine in combination with azithromycin was used to treat COVID-19 patients in the USA, although the mechanisms of the anti-COVID-19 effects remain unclear.
    keywords: azithromycin; cardiac; cardiovascular; chloroquine; cov-2; covid-19; disease; effects; hydroxychloroquine; infection; injury; patients; risk; sars; treatment
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        item: #3720 of 7819
          id: cord-300460-jh6h83n9
      author: Karnon, Jonathan
       title: The Case for a Temporary COVID-19 Income Tax Levy Now, During the Crisis
        date: 2020-04-16
       words: 1336
      flesch: 41
     summary: This means that the disutility of paying additional income tax during the COVID-19 crisis is reduced relative to the disutility of paying more income tax in normal times. The characteristics of the economic effects of the COVID-19 pandemic-constrained consumption and the negative externalities associated with widespread unemployment and worsening social determinants of health-inform an expectation that temporary income tax levies will increase population wellbeing over the medium term, i.e. the next 5-10 years.
    keywords: covid-19; crisis; effects; income
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        item: #3721 of 7819
          id: cord-300466-sk9iilum
      author: Kong, Wen-Hua
       title: Serologic Response to SARS-CoV-2 in COVID-19 Patients with Different Severity
        date: 2020-07-23
       words: 2466
      flesch: 42
     summary: In this study, we, compared the results of serologic tests and nucleic acid test (NAT) from a group of COVID-19 patients in Wuhan, and analyzed the serologic IgM and IgG antibody level of patients with different disease severity. In this study, two NMPA approved M-CLIA kits were used to detect the level of SARS-CoV-2 IgM and IgG antibodies in the serum of COVID-19 patients.
    keywords: antibody; cov-2; covid-19; patients; sars
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        item: #3722 of 7819
          id: cord-300471-osbp6eau
      author: Naruse, Keiko
       title: Does glycemic control rescue type 2 diabetic patients from COVID‐19‐related deaths?
        date: 2020-06-10
       words: 610
      flesch: 31
     summary: COVID-19 patients with diabetes have been reported to have higher mortality compared with non-diabetic COVID-19 patients, however, recent investigations indicated the importance of better glycemic control to avoid the death from COVID-19. They found higher risks of increased severity of pneumonia and mortality with increased inflammatory responses including higher levels of interleukin-6 (IL-6) and coagulation index, D-dimer, than in COVID-19 patients without other comorbidities, including diabetes (n=26)
    keywords: covid-19; patients
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        item: #3723 of 7819
          id: cord-300474-r5gms09p
      author: Mackey, Katherine
       title: Update Alert 2: Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults
        date: 2020-07-23
       words: 597
      flesch: 29
     summary: Heart A systematic review and meta-analysis to evaluate the clinical outcomes in COVID-19 patients on angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. Eur Heart J Cardiovasc Pharmacother Estimation of renin-angiotensin-aldosterone-system (RAAS)-inhibitor effect on COVID-19 outcome: a meta-analysis Predictors of severe or lethal COVID-19, including angiotensin converting enzyme inhibitors and angiotensin ii receptor blockers, in a sample of infected Italian citizens Clinical characteristics and disease progression in early-stage COVID-19 patients in South Korea Use of RAAS inhibitors and risk of clinical deterioration in COVID-19: results from an Italian cohort of 133 hypertensives Association of angiotensinconverting enzyme inhibitor or angiotensin receptor blocker use with COVID-19 diagnosis and mortality Is the use of ACE inb/ARBs associated with higher in-hospital mortality in Covid-19 pneumonia patients?
    keywords: angiotensin; covid-19
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        item: #3724 of 7819
          id: cord-300490-aslvqymx
      author: Rahman, Md. Estiar
       title: Physical inactivity and sedentary behaviors in the Bangladeshi population during the COVID-19 pandemic: An online cross-sectional survey
        date: 2020-10-30
       words: 4109
      flesch: 38
     summary: Survey questions included socio-demographics and an adapted version of the IPAQ-SF to assess physical activity and sedentary behaviors. Physical activity (PA) is regarded as a critical component of a healthy lifestyle and disease prevention
    keywords: activity; behaviors; covid-19; health; pandemic
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        item: #3725 of 7819
          id: cord-300508-po2zolo8
      author: Inoue, Gen
       title: Experience of an Orthopaedic Surgery Department Early During the COVID-19 Outbreak in Japan Including Real-Time Polymerase Chain Reaction Assay Results for SARS-CoV-2
        date: 2020-10-24
       words: 3949
      flesch: 43
     summary: The incidence of abnormal values, which are commonly noted in COVID-19 patients, were eosinopaenia 37.5%; lymphopaenia 18.8%; thrombocytopaenia 8.3%; and elevated prothrombin time 10.4%. In COVID-19 patients with pneumonia and abnormal findings on chest computed tomography, the reported signs/symptoms at onset included fever (98%), cough (76%), myalgia or fatigue (44%), sputum production (28%), headache (8%), haemoptysis (5%), and diarrhoea (3%); and after a median time of eight days from the onset of illness, dyspnoea developed in 55% of 41 patients [17] .
    keywords: cases; covid-19; number; patients; pcr; sars; surgery
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        item: #3726 of 7819
          id: cord-300517-41pr3dwa
      author: Zhang, Dan
       title: The clinical benefits of Chinese patent medicines against COVID-19 based on current evidence
        date: 2020-05-05
       words: 4792
      flesch: 20
     summary: In silico screening of Chinese herbal medicines with the potential to directly inhibit 2019 novel coronavirus Clinical features and treatment of COVID-19 patients in northeast Chongqing Protective effect of phillyrin on lethal LPS-induced neutrophil inflammation in zebrafish Phillyrin is an effective inhibitor of quorum sensing with potential as an anti-Pseudomonas aeruginosa infection therapy Protective effects of phillyrin against influenza A virus in vivo Efficacy of Xuebijing injection for sepsis (EXIT-SEP): protocol for a randomised controlled trial Microcirculatory disorders and protective role of Xuebijing in severe heat stroke Effects of radix ginseng on microbial infections: a narrative review Protective roles of ginseng against bacterial infection The characteristics and regularities of cardiac adverse drug reactions induced by Chinese materia medica: A bibliometric research and association rules analysis A review of cinnabar (HgS) and/or realgar (As4S4)-containing traditional medicines Study on cardiotoxicity and mechanism of Fuzi extracts based on metabonomics A review of traditional and current methods used to potentially reduce toxicity of Aconitum roots in Traditional Chinese Medicine Safety profile of traditional Chinese herbal injection: An analysis of a spontaneous reporting system in China Safety concerns of traditional Chinese medicine injections used in Chinese children Respiratory syncytial virus prophylaxis and the special population Do ethanol and metronidazole interact to produce a disulfiram-like reaction? Observation on clinical effect of modified Qingfeipaidu decoction in treatment of COVID-19 This work is supported by the Programs Foundation for Leading Talents in State Administration of Traditional Chinese Medicine of China-Qihuang scholars Project (10400633210004), the National Natural Science Foundation of China (Grant No. 81874349), and National special support plan for high-level talents (Plan of ten thousand people)-Famous Teacher Program to Professor Bing Zhang. As recommended in the Guideline on Diagnosis and Treatment of Coronavirus Disease 2019 (Revised 7th version) which was officially released by National Health Commission of the People's Republic of China, TCM could exert favorable effects for patients with different syndromes and distinct stages of COVID-19, contributing to infections in the periods of both medical observation and clinical treatment [23] .
    keywords: china; chinese; coronavirus; covid-19; cpms; disease; effects; injection; medicine; patients; tcm; treatment
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        item: #3727 of 7819
          id: cord-300541-5wea9w32
      author: Abdoul-Azize, Hamidou Taffa
       title: Social Protection as a Key Tool in Crisis Management: Learnt Lessons from the COVID-19 Pandemic
        date: 2020-09-01
       words: 3892
      flesch: 41
     summary: To access to the primary literature related to SPP executed in managing the COVID-19 pandemic, search terms (social protection, social protection programs, COVID-19 pandemic, social assistance, pandemic crises, social insurance, cash & inkind transfers, vulnerable groups, mitigation, pandemic crisis, COVID-19 breakout/coping strategy, crisis management, middle and high-income countries) have been used through WOS, Google scholar, ILO, World Bank, and WHO web sites. Types of multi-level governance Protecting people, promoting jobs: a survey of country employment and social protection policy responses to the global economic crisis, report to the G20 Leaders' Summit Social protection responses to the Covid-19 crisis Country responses in Asia and the Pacific Poverty, social protection and agriculture: levels and trends in data Global coronavirus cases exceed two million: live updates Crisis!
    keywords: countries; covid-19; crisis; pandemic; programs; protection; social; spp
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        item: #3728 of 7819
          id: cord-300550-l28tadhn
      author: Luers, Jan C
       title: Olfactory and Gustatory Dysfunction in Coronavirus Disease 19 (COVID-19)
        date: 2020-05-01
       words: 1756
      flesch: 56
     summary: Our study shows for the first time that both olfactory and gustatory dysfunction is very common in COVID-19 patients, with olfactory dysfunction even leveling the symptom 'cough' at > 70%. Others often see olfactory dysfunction as a standalone nasal symptom in COVID-19 patients.
    keywords: covid-19; olfactory; patients
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        item: #3729 of 7819
          id: cord-300551-o1da3zds
      author: Watson, James A
       title: Concentration-dependent mortality of chloroquine in overdose
        date: 2020-07-08
       words: 9933
      flesch: 41
     summary: Electrocardiograph QRS interval duration as a function of whole blood chloroquine concentrations. Whole blood chloroquine concentrations were measured on admission and at varying times subsequently.
    keywords: blood; chloroquine; clemessy; clemessy et; concentrations; covid-19; data; dose; et al; hydroxychloroquine; model; patients; poisoning; qrs; treatment
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        item: #3730 of 7819
          id: cord-300559-vuuxthx2
      author: Deng, Ming
       title: Obesity as a Potential Predictor of Disease Severity in Young COVID‐19 Patients: A Retrospective Study
        date: 2020-06-29
       words: 4170
      flesch: 49
     summary: [34, 35] , and the risk of thrombosis is high for severe COVID-19 patients Logistic regression analysis showed that male, high body mass index (especially obesity), elevated fasting blood glucose and urinary protein positive are all risk factors for severe young COVID‐19 patients.
    keywords: albumin; article; cases; copyright; covid-19; liver; obesity; patients; study
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        item: #3731 of 7819
          id: cord-300608-eju7wnb9
      author: Sheervalilou, Roghayeh
       title: COVID‐19 under spotlight: A close look at the origin, transmission, diagnosis, and treatment of the 2019‐nCoV disease
        date: 2020-05-26
       words: 7424
      flesch: 38
     summary: The first case of 2019 novel coronavirus pneumonia imported into Korea from Wuhan, China: Implication for infection prevention and control measures Updates on Wuhan 2019 novel coronavirus epidemic Inhibition of human coronavirus 229E infection in human epithelial lung cells (L132) by chloroquine: Involvement of p38 MAPK and ERK Prevalence and risk factors for posttraumatic stress disorder: A cross-sectional study among survivors of the Wenchuan Dipeptidylpeptidase IV from bench to bedside: An update on structural properties, functions, and clinical aspects of the enzyme DPP IV Positive RT-PCR test results in patients recovered from COVID-19 Sex differences in clinical findings among patients with coronavirus disease 2019 (COVID-19) and severe condition Early transmission dynamics in Wuhan, China, of novel coronavirusinfected pneumonia Hypokalemia and clinical implications in patients with coronavirus disease 2019 (COVID-19) Case of the index patient who caused tertiary transmission of Coronavirus disease 2019 in Korea: The application of lopinavir/ ritonavir for the treatment of COVID-19 pneumonia monitored by quantitative RT-PCR Therapeutic effects of dipyridamole on COVID-19 patients with coagulation dysfunction The reproductive number of COVID-19 is higher compared to SARS coronavirus Molecular epidemiology, evolution and phylogeny of SARS coronavirus Application of artificial neural networks for automated analysis of cystoscopic images: 5.3 | COVID-19 detection tests: Pathogenic laboratory testing, real-time RT-PCR, and sequencing of nucleic acid Table 3 (Ai et al., 2020; Bai et al., 2020; Chen, Zhao, et al., 2020; Shi et al., 2020; Tian et al., 2020; Wang, Kang, et al., 2020; Wu & McGoogan, 2020; Yan et al., 2020; Yang et al., 2020) and Table 4 represent 2020 studies on diagnosis of COVID-19 infected patients and related clinical trials, respectively.
    keywords: cases; china; clinical; coronavirus; cov-2; covid-19; diagnosis; disease; et al; human; infection; novel; patients; pneumonia; sars; study; treatment
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        item: #3732 of 7819
          id: cord-300619-uu3e4pjw
      author: Tan, Wanqiu
       title: Is Returning to Work during the COVID-19 Pandemic Stressful? A Study on Immediate Mental Health Status and Psychoneuroimmunity Prevention Measures of Chinese Workforce
        date: 2020-04-23
       words: 4809
      flesch: 37
     summary: The IES-R, DASS-21 and ISI scores of study respondents after they were approved to return to work All respondents (n=673) In contrast, personal psychoneuroimmunity prevention measures including hand hygiene and wearing face masks as well as organizational measures including significant improvement of workplace hygiene and concerns from the company were associated with less severe psychiatric symptoms (p<0.05).
    keywords: covid-19; health; measures; psychoneuroimmunity; respondents; symptoms; work; workplace
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        item: #3733 of 7819
          id: cord-300621-0e35o0rk
      author: Engelman, Daniel T.
       title: Commentary: Rethinking Surgical Protocols in the Covid-19 Era
        date: 2020-04-13
       words: 318
      flesch: 18
     summary: Preparing for Community Transmission of COVID-19 in the United States Does nasal screening for Staphyloccus aureus before surgery compromise healthcare professional safety in COVID-19 era? Effect of a preoperative decontamination protocol on surgical site infections in patients undergoing elective orthopedic surgery with hardware implantation Staphylococcus Aureus Prevention Strategies in Cardiac Surgery: A Cost-Effectiveness Analysis Logic dictates that until a more critical assessment is made of the risk posed by this practice, routine preoperative nasal swabbing for identification of Staph carriers in our patient population should be reconsidered.
    keywords: covid-19
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        item: #3734 of 7819
          id: cord-300640-9pvhaz8q
      author: Parackova, Zuzana
       title: Disharmonic Inflammatory Signatures in COVID-19: Augmented Neutrophils’ but Impaired Monocytes’ and Dendritic Cells’ Responsiveness
        date: 2020-09-29
       words: 6003
      flesch: 38
     summary: We observed a statistically significant decrease in baseline CD15, HLA-DR, PD-L1, and CD62L expression on COVID-19 neutrophils compared to healthy donors, while CD66b and CD11b expressions were similar to controls ( Figure 1A ). LPS stimulation induced increased PD-L1, HLA-DR, and CD15 surface expression in healthy donors, but significantly less so in COVID-19 neutrophils.
    keywords: cells; clone; covid-19; disease; expression; figure; monocytes; neutrophils; patients; pbmcs; sars; ssrna; stimulation
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        item: #3735 of 7819
          id: cord-300651-4didq6dk
      author: Sun, Ya-Jun
       title: Clinical Features of Fatalities in Patients With COVID-19
        date: 2020-07-14
       words: 1791
      flesch: 48
     summary: We constituted a cohort of COVID-19 deaths through retrieving the clinical information on COVID-19 fatalities from nonduplicating incidental reports in Chinese provincial and metropolitan city Health Commission and other governmental official websites between January 23 and March 10, 2020. CONCLUSIONS: COVID-19 deaths are mainly elderly and patients with chronic diseases especially cardiovascular disorders and diabetes.
    keywords: covid-19; death; failure; study
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        item: #3736 of 7819
          id: cord-300689-dz6lybgi
      author: Jarman, Molly P.
       title: The Surgical Health Services Research Agenda for the COVID-19 Pandemic
        date: 2020-06-01
       words: 2441
      flesch: 27
     summary: 5 Long-term guidelines for pre-operative COVID-19 screening are essential for safe return to routine surgical care. The widespread impact of COVID-19 on surgical departments illustrates the importance of surgical care in the overall healthcare system.
    keywords: care; covid-19; impact; outcomes; pandemic; patients; surgery
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        item: #3737 of 7819
          id: cord-300712-gc8770l9
      author: Ruch, Yvon
       title: Rapid Radiological Worsening and Cytokine Storm Syndrome in COVID-19 Pneumonia
        date: 2020-07-02
       words: 774
      flesch: 41
     summary: COVID-19: consider cytokine storm syndromes and immunosuppression On the alert for cytokine storm: immunopathology in COVID-19 Impact of low-dose tocilizumab on mortality rate in patients with COVID-19 related pneumonia Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: a single center Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Low-cost dexamethasone reduces death by up to one third in hospitalised patients with severe respiratory complications of COVID-19 In June 2020, the investigators of the RECOVERY (Randomised Evaluation of COVid-19 thERapY) trial, which enrolled over 11,500 patients in the UK, reported a reduction in death of up to one-third in hospitalised patients with severe respiratory complications of COVID-19 treated with dexamethasone [6] .
    keywords: covid-19; patients; syndrome
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        item: #3738 of 7819
          id: cord-300716-urmogf97
      author: Briguglio, Matteo
       title: Disentangling the Hypothesis of Host Dysosmia and SARS-CoV-2: The Bait Symptom That Hides Neglected Neurophysiological Routes
        date: 2020-06-05
       words: 9895
      flesch: 30
     summary: The gut-associated lymphoid tissue with the mesenteric lymph nodes and the microfold cells are in charge of the sampling, phagocytosis, and transcytosis of luminal molecules, viruses, bacteria, parasites, and dietary supplements (Briguglio et al., 2020a) , being critical for the first-line immune responses of the host (Mabbott et al., 2013) . Among the circumventricular organs, the area postrema is an important local site that allows the touching of circulating substances with the brain parenchyma (Briguglio et al., 2018) .
    keywords: access; acute; brain; brainstem; cells; coronavirus; cov-2; covid-19; et al; host; infection; nasal; nerve; neuronal; olfactory; patients; sars; system; virus
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        item: #3739 of 7819
          id: cord-300729-35meen0h
      author: Miller, Aaron
       title: Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study
        date: 2020-03-28
       words: 2744
      flesch: 45
     summary: key: cord-300729-35meen0h authors: Miller, Aaron; Reandelar, Mac Josh; Fasciglione, Kimberly; Roumenova, Violeta; Li, Yan; Otazu, Gonzalo H title: Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study date: 2020-03-28 journal: nan DOI: 10.1101/2020.03.24.20042937 sha: doc_id: 300729 cord_uid: 35meen0h COVID-19 has spread to most countries in the world. establishment of universal BCG vaccination and the mortality rate, consistent with the idea that the earlier that a policy was established, the larger fraction of the elderly population would be protected (see Figure 2 , left panel).
    keywords: bcg; countries; covid-19; policy; vaccination
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        item: #3740 of 7819
          id: cord-300742-hsfh4hw9
      author: Ghoreishi, Abdoreza
       title: Stroke care trends during COVID-19 pandemic in Zanjan Province, Iran. From the CASCADE Initiative: statistical analysis plan and preliminary results
        date: 2020-09-16
       words: 3961
      flesch: 42
     summary: The results of this research will contribute to a similar analysis of the larger CASCADE dataset in order to confirm findings at a global scale and improve measures to ensure the best quality of care for stroke patients during the COVID-19 pandemic. The results of this research will contribute to a similar analysis of the larger CASCADE dataset in order to confirm findings at a global scale and improve measures to ensure the best quality of care for stroke patients during the COVID-19 pandemic.
    keywords: care; changes; covid-19; hospital; pandemic; patients; rate; stroke; study; time
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        item: #3741 of 7819
          id: cord-300750-huyl21vz
      author: Shagam, Lev
       title: Untangling factors associated with country-specific COVID-19 incidence, mortality and case fatality rates during the first quarter of 2020
        date: 2020-04-27
       words: 3773
      flesch: 47
     summary: key: cord-300750-huyl21vz authors: Shagam, Lev title: Untangling factors associated with country-specific COVID-19 incidence, mortality and case fatality rates during the first quarter of 2020 date: 2020-04-27 journal: nan DOI: 10.1101/2020.04.22.20075580 sha: doc_id: 300750 cord_uid: huyl21vz At early stages of the COVID-19 pandemic which we are experiencing, the publicly reported incidence, mortality and case fatality rates (CFR) vary significantly between countries. Country hemisphere demonstrated significant correlation only with mortality (p = 0.17 and 0.036) whereas population density (p = 0.94 and p = 0.75) and latitude (p = 0.61 and 0.059) did not reach significance in our model.
    keywords: countries; country; covid-19; incidence; mortality; number
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        item: #3742 of 7819
          id: cord-300763-3ateeei3
      author: Vannabouathong, Christopher
       title: Novel Coronavirus COVID-19: Current Evidence and Evolving Strategies
        date: 2020-05-06
       words: 6149
      flesch: 45
     summary: Nat Microbiol Clinical virology Epidemiology, genetic recombination, and pathogenesis of coronaviruses Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Clinical features of patients infected with 2019 novel coronavirus in Wuhan Indirect virus transmission in cluster of COVID-19 cases A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Evidence of SARS-CoV-2 infection in returning travelers from Wuhan, China Transmission of 2019-nCoV infection from an asymptomatic contact in Germany Presumed asymptomatic carrier transmission of COVID-19 Transmission interval estimates suggest presymptomatic spread of COVID-19. Global News Canadian company announces COVID-19 vaccine candidate.
    keywords: cases; china; coronavirus; cov-2; covid-19; disease; health; novel; patients; people; sars; spread; symptoms
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        item: #3743 of 7819
          id: cord-300776-owrrwd08
      author: Safavi, Farinaz
       title: B-cell depleting therapies may affect susceptibility to acute respiratory illness among patients with Multiple Sclerosis during the early COVID-19 epidemic in Iran
        date: 2020-05-13
       words: 3376
      flesch: 43
     summary: Patients on B-cell depleting antibodies had 3.6 times higher risk of being in the COVID-19-suspect group as compared to patients on none-lymphocyte-depleting and non-cell trafficking inhibitor DMTs (95%CI: 1.45, 8.68, p-value=0.005). Patients who were on a B-cell depleting antibody, as compared to patients on other none-lymphocyte-depleting, non-cell-trafficking inhibitor DMTs, had a higher risk of being in the COVID-19 suspected group.
    keywords: cell; covid-19; disease; group; patients; suspect
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        item: #3744 of 7819
          id: cord-300777-6u6nqv2f
      author: Oladeru, Oluwadamilola T.
       title: A call to protect patients, correctional staff and healthcare professionals in jails and prisons during the COVID-19 pandemic
        date: 2020-07-02
       words: 1375
      flesch: 40
     summary: As a result, we must take urgent action now to develop correctional healthcare strategies that protect the health and safety of patients, correctional staff and healthcare professionals. Incarcerated people and those in contact with them, including over 450,000 correctional officers and thousands of prison healthcare staff, are at significant risk of COVID-19 exposure.
    keywords: covid-19; facilities; healthcare; staff
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        item: #3745 of 7819
          id: cord-300792-hpyywul0
      author: Thaler, M.
       title: Disruption of joint arthroplasty services in Europe during the COVID-19 pandemic: an online survey within the European Hip Society (EHS) and the European Knee Associates (EKA)
        date: 2020-05-02
       words: 2946
      flesch: 46
     summary: These type of approach both by the health and hospital authorities and the orthopaedic surgeons has several undoubtable reasons: save resources for COVID-19 patients (medical and nurse staff, hospital beds, intensive care units, economical resources), to reduce the risks of contamination (of the staff, of the patients of the whole community) in an open environment such as the hospitals which are difficult to be controlled, to avoid contamination of fragile patients that are the majority of TJA patients especially in the post-operative time, to guarantee a safe and effective rehabilitation time. Findings of the survey in more detail are provided in Tables 2, 3 The most important finding of the present study was the massive cutback in primary as well as revision TJA service in Europe during the COVID-19 pandemic.
    keywords: arthroplasty; covid-19; pandemic; patients; surgeons; survey; tja
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        item: #3746 of 7819
          id: cord-300802-2y2oxss4
      author: Kim, Judith
       title: Effect of the COVID-19 Pandemic on Outcomes for Patients Admitted with Gastrointestinal Bleeding in New York City
        date: 2020-05-13
       words: 849
      flesch: 36
     summary: We sought to assess differences in hospital length of stay for gastrointestinal bleeding before and during the COVID-19 pandemic. This is the first study to evaluate the impact of the COVID-19 pandemic on gastrointestinal bleeding outcomes.
    keywords: pandemic; patients
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        item: #3747 of 7819
          id: cord-300805-apli48ih
      author: Augoustides, John G.
       title: The Renin-Angiotensin-Aldosterone System in Coronavirus Infection – current considerations during the pandemic
        date: 2020-04-16
       words: 1469
      flesch: 31
     summary: 1-2 ; 6-7 The purpose of this freestanding editorial is to highlight the considerations concerning the RAAS in patients presenting with severe coronavirus disease 2019 . [14] The coexisting conditions such as hypertension, older age, diabetes, cardiovascular disease have all been reported to be more common in patients with severe COVID-19 requiring intensive care.
    keywords: angiotensin; coronavirus; covid-19; patients
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        item: #3748 of 7819
          id: cord-300811-l4y7df2f
      author: Aggarwal, Gaurav
       title: Association of Cardiovascular Disease with Coronavirus Disease 2019 (COVID-19) Severity: A Meta-Analysis
        date: 2020-04-28
       words: 2541
      flesch: 39
     summary: key: cord-300811-l4y7df2f authors: Aggarwal, Gaurav; Cheruiyot, Isaac; Aggarwal, Saurabh; Wong, Johnny; Lippi, Giuseppe; Lavie, Carl J.; Henry, Brandon M.; Sanchis-Gomar, Fabian title: Association of Cardiovascular Disease with Coronavirus Disease 2019 (COVID-19) Severity: A Meta-Analysis date: 2020-04-28 journal: Curr Probl Cardiol DOI: 10.1016/j.cpcardiol.2020.100617 sha: doc_id: 300811 cord_uid: l4y7df2f Observational studies have reported an association between underlying cardiovascular diseases (CVD) and worse prognosis in COVID-19 patients, but this still remains unclear. We conducted a meta-analysis of recent studies that reported the association of CVD with worse prognosis and increased mortality in COVID-19 patients.
    keywords: covid-19; cvd; disease; mortality; patients; studies
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        item: #3749 of 7819
          id: cord-300817-cxc00k0d
      author: Saha, Jay
       title: Indoor air pollution (IAP) and pre-existing morbidities among under-5 children in India: are risk factors of coronavirus disease (COVID-19)?()
        date: 2020-07-15
       words: 3254
      flesch: 37
     summary: So, compared to the other previous studies in India, this type of study is yet not done, considering this huge research gap and novelty, this study also aims to find out the risk factors associated with the Coronavirus disease (COVID-19) among under-five children using pre-existing morbidity conditions and indoor air pollution environmental factors which are solid biomass cooking fuel and indoor smoking cigarettes and also with current case fatality ratio (CFR) and recovery rate (RR) of the COVID-19 disease in the high focusing states and union territories of India which are in a risk zone. key: cord-300817-cxc00k0d authors: Saha, Jay; Chouhan, Pradip title: Indoor air pollution (IAP) and pre-existing morbidities among under-5 children in India: are risk factors of coronavirus disease (COVID-19)?
    keywords: air; children; coronavirus; covid-19; india; risk
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        item: #3750 of 7819
          id: cord-300848-0igfcixy
      author: Meijers, Björn
       title: The clinical characteristics of coronavirus-associated nephropathy
        date: 2020-09-02
       words: 1689
      flesch: 49
     summary: To date, kidney histology of COVID-19 patients with a less severe clinical course has not been reported. While most patients are asymptomatic or have minor symptoms, a minority of patients develop more serious and potentially life-threatening respiratory disease [2] .
    keywords: covid-19; kidney; patients; sars
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        item: #3751 of 7819
          id: cord-300855-vba552kh
      author: Dungar, Keval Dhanji
       title: The lessons to learn with regards to hospital admissions during the COVID-19 pandemic, a Commentary on “acute care surgery during the COVID-19 pandemic in Spain: Changes in volume, causes and complications. A multicentre retrospective cohort study”
        date: 2020-10-08
       words: 692
      flesch: 55
     summary: Delayed presentations during the COVID-19 pandemic have contributed to death in major conditions such as diabetic ketoacidosis, sepsis and appendicitis in children [3] . NEJM Catalyst -Innovations in Care Delivery Delayed access to care and late presentations in children during the COVID-19 pandemic: a snapshot J o u r n a l P r e -p r o o f survey of 4075 paediatricians in the UK and Ireland
    keywords: covid-19; pandemic
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        item: #3752 of 7819
          id: cord-300866-cso6l6ze
      author: Bao, Yi
       title: Clinical Features of COVID-19 in a Young Man with Massive Cerebral Hemorrhage—Case Report
        date: 2020-05-23
       words: 4256
      flesch: 46
     summary: The treatment of COVID-19 patients with intracerebral hemorrhage suggesting that antiviral treatment was effective. Contact history of the epidemic area and close contact history of COVID-19 confirmed patients were denied.
    keywords: blood; clinical; cov-2; covid-19; density; hemorrhage; infection; patient; sars; treatment
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        item: #3753 of 7819
          id: cord-300889-3tzg6few
      author: Yasri, S
       title: Re: Testing recommendation for COVID-19 and planned surgery
        date: 2020-06-28
       words: 275
      flesch: 47
     summary: Br J Oral Maxillofac Surg DOI: 10.1016/j.bjoms.2020.04.052 sha: doc_id: 300889 cord_uid: 3tzg6few nan Please cite this article in press as: Yasri S, Wiwanitkit V. Re We found that the publication on Testing recommendation for COVID-19 (SARS-CoV-2) in patients planned for surgery -continuing the service and suppressing the pandemic is very interesting. Testing recommendation for COVID-19 (SARS-CoV-2) in patients planned for surgery -continuing the service and 'suppressing' the pandemic Carpal fracture and COVID-19 infection: observation from Thailand Detection and analysis of nucleic acid in various biological samples of COVID-19 patients Comparison of nasopharyngeal and oropharyngeal swabs for SARS-CoV-2 detection in 353 patients received tests with both specimens simultaneously We have no conflicts of interest.
    keywords: covid-19
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        item: #3754 of 7819
          id: cord-300899-yi2mx91a
      author: Kaur, Satinder
       title: Understanding COVID-19 transmission, health impacts and mitigation: timely social distancing is the key
        date: 2020-07-18
       words: 5354
      flesch: 48
     summary: Python programming is conducted for change point analysis (CPA) using Bayesian probability approach for understanding the impact of restrictions and mitigation methods in terms of either increase or stagnation in number of COVID-19 cases for eight countries. COVID-19 cases were reported with individuals having no travel history, suggesting that local transmission occurred in these countries.
    keywords: cases; china; countries; cov-2; covid-19; et al; number; population; sars; transmission; virus
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        item: #3755 of 7819
          id: cord-300911-cl7s47wb
      author: English, W.
       title: Surgical training during the COVID‐19 pandemic – the cloud with a silver lining?
        date: 2020-07-14
       words: 558
      flesch: 40
     summary: General surgical training has not been immune to these necessary changes, anecdotally resulting in reduced operating frequency, procedure number and case type available to higher surgical trainees. key: cord-300911-cl7s47wb authors: English, W.; Vulliamy, P.; Banerjee, S.; Arya, S. title: Surgical training during the COVID‐19 pandemic – the cloud with a silver lining? date: 2020-07-14 journal:
    keywords: trainee; training
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        item: #3756 of 7819
          id: cord-300963-1n1f8mf2
      author: Gajendran, Mahesh
       title: Inflammatory bowel disease amid the COVID-19 pandemic: impact, management strategies, and lessons learned
        date: 2020-10-12
       words: 6697
      flesch: 43
     summary: Patients with COVID-19 have lymphopenia, whereas in IBD patients, lymphocyte levels are usually normal or elevated. Hence, there is an ongoing concern over the impact of COVID-19 on IBD patients and their susceptibility to it.
    keywords: bowel; cells; coronavirus; covid-19; disease; ibd; ibd patients; infection; management; pandemic; patients; risk; rna; sars; study
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        item: #3757 of 7819
          id: cord-300964-knc0ruou
      author: Hoffman, Tove
       title: Evaluation of a COVID-19 IgM and IgG rapid test; an efficient tool for assessment of past exposure to SARS-CoV-2
        date: 2020-04-14
       words: 2553
      flesch: 46
     summary: In this study we evaluated a commercial rapid test for detection of SARS-CoV-2-specific IgM and IgG. For the evaluation, samples from COVID-19 cases, obtained during disease or convalescence and previously confirmed by PCR, were used as 'true positives'. According to the manufacturer, the specificity has been evaluated on 14 PCR-negative samples and was found to be 100% for both IgM and IgG, while the sensitivity evaluated on COVID-19 cases was calculated at 87.9% for IgM and 97.2% for IgG. The results by Li et al.
    keywords: covid-19; igg; igm; positive; sars; test
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        item: #3758 of 7819
          id: cord-300978-busx8w6s
      author: Apetrii, Mugurel
       title: A brand-new cardiorenal syndrome in the Coronavirus Disease- 2019 (COVID-19) setting
        date: 2020-06-04
       words: 3007
      flesch: 33
     summary: In COVID-19 patients, it was noted that viral load, lung injury (via the partial pressure of oxygen:fraction of inspired oxygen ratio) and higher levels of angiotensin II were all positively correlated [42] . Although early reports suggested a lower incidence (3-9%) of AKI in COVID-19 patients (in the Chinese population)
    keywords: ace2; acute; angiotensin; coronavirus; covid-19; patients; sars; syndrome
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        item: #3759 of 7819
          id: cord-300991-ipy24zxp
      author: Khan, Amira Sayed
       title: Obesity and COVID-19: Oro-Naso-Sensory Perception
        date: 2020-07-08
       words: 5986
      flesch: 41
     summary: There is no direct report available on the loss of these chemical senses in obese COVID-19 patients. Epidemiological data confirm that there is an increased rate of pneumonia and RTI in COVID-19 obese patients [12] .
    keywords: cells; cov-2; covid-19; infection; inflammation; loss; obese; obesity; olfactory; patients; sars; taste; tnf
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        item: #3760 of 7819
          id: cord-300995-tqz2bkdo
      author: Tagliaferri, Luca
       title: Skin cancer triage and management during COVID‐19 pandemic
        date: 2020-04-25
       words: 1413
      flesch: 36
     summary: We suggest practical recommendations about follow-up and treatment of skin cancer patients during the COVID-19 pandemic. A useful approach, as already suggested by other authors, is to identify the different classes of priorities, both for the patients and for health professionals [5, 6] .Only a few national and international societies have released specific recommendations for skin cancer patients [7] .
    keywords: cancer; covid-19; patients; risk
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        item: #3761 of 7819
          id: cord-300997-z903uyht
      author: Choudhury, Ehsanul Karim
       title: An Invited Commentary on “The Surgeon and the COVID-19 pandemic”
        date: 2020-05-19
       words: 749
      flesch: 48
     summary: • Elective surgical activity has been largely cancelled and invasive investigations such as endoscopy have been abandoned. Much of this perspective looks at the challenges of re-establishing elective surgical services.
    keywords: covid-19; surgeons
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        item: #3762 of 7819
          id: cord-301000-ozm5f5dy
      author: Naqvi, Zainab Batul
       title: A Wench’s Guide to Surviving a ‘Global’ Pandemic Crisis: Feminist Publishing in a Time of COVID-19
        date: 2020-09-04
       words: 8600
      flesch: 43
     summary: Our insistence that academic publishing, and feminist publishing in particular, be seen as a political endeavour drives a lot of our editorial policies including an emphasis on the importance of Global South scholarship, employing decolonising techniques in our editorial practice, our involvement in the recent Global South writing workshops (Naqvi et al. 2019 ) and our continuing support for early career researchers (ECRs), particularly those from marginalised or minoritised communities. The current paradigm, however, provides us with another opportunity to look at the mode of production operating in journal publishing, one that we at FLS are implicated in and have long been critical of (Fletcher et al. 2016
    keywords: access; collective; covid-19; disease; editorial; feminist; global; health; journal; pandemic; publishing; research; social; time; women; work
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        item: #3763 of 7819
          id: cord-301011-xbuqd0j5
      author: Felten-Barentsz, Karin M
       title: Recommendations for Hospital-Based Physical Therapists Managing Patients With COVID-19
        date: 2020-06-18
       words: 3953
      flesch: 32
     summary: Therefore, we recommend to not detach the ventilation system for the purpose of respiratory function testing, respiratory muscle training, or breathing exercises. The team may decide that benefits of respiratory muscle training outweigh the safety risks.
    keywords: covid-19; hospital; mobilization; muscle; patients; recommendations; support; therapists; training
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        item: #3764 of 7819
          id: cord-301025-cf2jcw6x
      author: Musca, Serban C.
       title: A Simple Bayesian Method for Evaluating Whether Data From Patients With Rheumatic Diseases Who Have Been Under Chronic Hydroxychloroquine Medication Since Before the COVID-19 Outbreak Can Speak to Hydroxychloroquine's Prophylactic Effect Against Infection With SARS-CoV-2
        date: 2020-08-13
       words: 4369
      flesch: 46
     summary: Moreover, at the other extreme of pop gen COVID-19 prevalence values considered, 6,000 per 100,000, one can have more than one HCQpa in 23 (93 out of 2,000) presenting with COVID-19 and still correctly conclude that COVID-19 prevalence is lower in the HCQpa than in pop gen This can be achieved with relative ease by considering whether COVID-19 prevalence is significantly lower in HCQpa than in the general population (i.e., all people that are not HCQpa).
    keywords: cov-2; covid-19; hcqpa; prevalence; sars
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        item: #3765 of 7819
          id: cord-301026-spgidqh3
      author: Das, Shaoli
       title: In silico Drug Repurposing to combat COVID-19 based on Pharmacogenomics of Patient Transcriptomic Data
        date: 2020-06-30
       words: 4202
      flesch: 34
     summary: Using the drug perturbational data sets from CMAP 14 , we found the drugs that affected the gene expression of these targets (differences in gene expression at 24 hours vs. 6 hours of drug treatment). The drug perturbational data set containing dose-and time-dependent transcriptomic pro les upon drug treatments in human cell lines was collected from CMAP 14 .
    keywords: cell; covid-19; data; drugs; infection; pathways; patients; sars; transcriptomic
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        item: #3766 of 7819
          id: cord-301027-b9urhbkh
      author: Li, R.
       title: Differences of clinical and imaging findings in multiple generations of secondary COVID-19 infection in Xi'an, China
        date: 2020-05-25
       words: 4141
      flesch: 43
     summary: Hypertension (6.9% of first-generation, 23.1% of second-generation vs. 28.6% of third-generation infections, p=0.138) was the most common comorbidity in all of multiple generation patients. In our study, we focused on whether there are differences in clinical characteristics and chest CT signs among multiple generation patients with COVID-19 infection.
    keywords: cases; covid-19; generation; medrxiv; patients; pneumonia; preprint
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        item: #3767 of 7819
          id: cord-301035-dz8642qx
      author: Rasheed, Jawad
       title: A Survey on Artificial Intelligence Approaches in Supporting Frontline Workers and Decision Makers for COVID-19 Pandemic
        date: 2020-10-10
       words: 6139
      flesch: 30
     summary: Table V lists the other identified COVID-19 AI-based applications that utilize respiratory or coughing data. A Capsule Network-based Framework for Identification of COVID-19 cases from X-ray Images Finding Covid-19 from Chest X-rays using Deep Learning on a Small Dataset Deep Learning on Chest X-ray Images to Detect and Evaluate Pneumonia Cases at the Era of COVID-19 A web-based Diagnostic Tool for COVID-19 Using Machine Learning on Chest Radiographs (CXR) Detection of Coronavirus (COVID-19) Associated Pneumonia based on Generative Adversarial Networks and a Fine-Tuned Deep Transfer Learning Model using Chest X-ray Dataset COVID-MobileXpert: On-Device COVID-19
    keywords: chest; coronavirus; covid-19; data; deep; detection; disease; images; learning; machine; model; pandemic; ray
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        item: #3768 of 7819
          id: cord-301036-x06m11e0
      author: Alfuraih, Abdulrahman M.
       title: Point of care lung ultrasound in COVID-19: hype or hope?
        date: 2020-08-28
       words: 2348
      flesch: 48
     summary: A preliminary study on the ultrasonic manifestations of Peripulmonary lesions of Non-Critical novel coronavirus pneumonia (COVID-19 Proposal for international standardization of the use of lung ultrasound for COVID-19 patients; a simple, quantitative, reproducible method Our Italian experience using lung ultrasound for identification, grading and serial follow-up of severity of lung involvement for management of patients with COVID-19 Lung ultrasound and computed tomographic findings in pregnant woman with COVID-19 Lung ultrasound and B-lines quantification inaccuracy: B sure to have the right solution COVID-19 outbreak: less stethoscope, more ultrasound The role of ultrasound in COVID-19 patient management On lung ultrasound patterns specificity in the management of COVID-19 patients What's new in lung ultrasound during the COVID-19 pandemic Clue: COVID-19 lung ultrasound in emergency department Soldati et al 12 proposed an unvalidated protocol to perform LU in COVID-19 patients.
    keywords: covid-19; lines; lung; pcr; ultrasound
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        item: #3769 of 7819
          id: cord-301052-qdhkwa4s
      author: Al-Tammemi, Ala'a B.
       title: The Battle Against COVID-19 in Jordan: An Early Overview of the Jordanian Experience
        date: 2020-05-07
       words: 3621
      flesch: 39
     summary: Jordan is considered a touristic country and a main connection point for many flights and trips within the region, and this, along with the noticeable increase in number of COVID-19 cases globally, has meant that the government has started to implement (periodically revised) strict rules and measures relating to travel, education, religious and social events, as well as working within various industries (17) . The decisions about international travel have progressed through many stages that accompanied the growth in the number of COVID-19 cases globally, especially in countries that have been struck severely by the disease.
    keywords: covid-19; curfew; disease; health; jordan; measures; public; spread
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        item: #3770 of 7819
          id: cord-301061-bekyn1k2
      author: Meschi, Tiziana
       title: Reorganization of a large academic hospital to face COVID‐19 outbreak: The model of Parma, Emilia‐Romagna region, Italy
        date: 2020-05-20
       words: 625
      flesch: 39
     summary: Reconversion of other medical wards of the hospital, located in other buildings, with activation of a dedicated mobile CT, has then been performed with increasing patient flows (final capacity >600 beds). If positive, patients are transferred either to infectious disease unit or to internal medicine ward clusters exclusively dedicated to COVID-19 management.
    keywords: covid-19; hospital; wards
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        item: #3771 of 7819
          id: cord-301067-wk3cf0b7
      author: Corpus-Mendoza, Asiel N.
       title: Decrease of mobility, electricity demand, and NO2 emissions on COVID-19 times and their feedback on prevention measures
        date: 2020-11-01
       words: 2539
      flesch: 41
     summary: key: cord-301067-wk3cf0b7 authors: Corpus-Mendoza, Asiel N.; Ruiz-Segoviano, Hector S.; Rodríguez-Contreras, Sergio F.; Yañez-Dávila, David; Hernández-Granados, Araceli title: Decrease of mobility, electricity demand, and NO2 emissions on COVID-19 times and their feedback on prevention measures date: 2020-11-01 journal: Sci Total Environ DOI: 10.1016/j.scitotenv.2020.143382 sha: doc_id: 301067 cord_uid: wk3cf0b7 The spread of coronavirus disease 2019 (COVID-19) on 2020 has affected human activities in a way never documented in modern history. In this case, we identify and discuss the early effort of Latin-American countries to successfully delay the spread of the virus by implementing prevention measures before the fast growth of COVID-19 cases in comparison to European countries.
    keywords: air; covid-19; decrease; electricity; measures; mobility; quality
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        item: #3772 of 7819
          id: cord-301082-sikgk58i
      author: Breevoort, Arnar
       title: High-altitude populations need special considerations for COVID-19
        date: 2020-07-01
       words: 1118
      flesch: 35
     summary: In these tests, the majority of commercial ventilators failed at high altitude, delivering tidal volumes with up to 40% error from the set volume 10 . We argue that high altitude human populations require special attention to access the international supply of ventilators.
    keywords: altitude; countries; covid-19; ventilators
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        item: #3773 of 7819
          id: cord-301083-nnh95i0k
      author: Jumreornvong, Oranicha
       title: Telemedicine and Medical Education in the Age of COVID-19
        date: 2020-09-10
       words: 4234
      flesch: 31
     summary: Training medical students to deliver high-quality, secure, and personalized health care through telemedicine will prepare the next generation of physicians to conscientiously use these technologies and meet a growing need for telehealth services. Schools could use the following learning vehicles to help medical students explore these domains: (1) asynchronous lectures covering telehealth history; (2) discussions on applications, ethics, safety, etiquette, and patient considerations; (3) faculty-supervised standardized patient telehealth encounters; and (4) hands-on diagnostic or therapeutic procedures using telehealth equipment.
    keywords: care; covid-19; education; health; medical; patient; providers; students; telehealth; telemedicine; training
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        item: #3774 of 7819
          id: cord-301106-qskwujpa
      author: Gambato, Martina
       title: Clinical implications of COVID-19 in patients with chronic liver disease and liver tumor
        date: 2020-06-05
       words: 1670
      flesch: 35
     summary: Patients with chronic liver disease and liver cancer should, therefore, follow specific measures and precautions to avoid clinical complications related to COVID-19. Specific ACE2 expression in cholangiocytes may cause liver damage after 2019-nCoV infection Pathological findings of COVID-19 associated with acute respiratory distress syndrome Coronavirus disease 2019 and prevalence of chronic liver disease: a meta-analysis Clinical characteristics of coronavirus disease 2019 in China COVID-19 and the liver: little cause for concern Acute on chronic liver failure from novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Care of patients with liver disease during the COVID-19 pandemic: EASL-ESCMID position paper Prevention of SARS-CoV-2 infection in patients with decompensated cirrhosis SARS-CoV-2 Transmission in patients with cancer at a Tertiary Care Hospital in Wuhan, China Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan Management of cancer surgery cases during the COVID-19 pandemic: considerations Lampertico P (2020) Management of hepatocellular carcinoma in the time of COVID-19
    keywords: covid-19; disease; liver; patients
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        item: #3775 of 7819
          id: cord-301115-sedfbjlw
      author: Han, Mingfeng
       title: Assessing SARS-CoV-2 RNA levels and lymphocyte/T cell counts in COVID-19 patients revealed initial immune status as a major determinant of disease severity
        date: 2020-08-28
       words: 4582
      flesch: 47
     summary: Severe patients additionally met at least one of the following conditions: (1) shortness of breath, RR ≥ 30 times/min, (2) oxygen saturation (resting state) ≤ 93%, or (3) PaO 2 / FiO 2 ≤ 300 mmHg. PCA was firstly performed with R package factoextra to identify correlating variables for distinguishing severe patients from mild patients (Figure Suppl 3A) .
    keywords: cases; counts; covid-19; disease; fig; levels; patients; sars
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        item: #3776 of 7819
          id: cord-301162-ux40twpt
      author: Chiaravalloti, Nancy D.
       title: The emotional impact of the COVID-19 pandemic on individuals with progressive multiple sclerosis
        date: 2020-08-19
       words: 4800
      flesch: 39
     summary: Only 57% of respondents reported any interaction with their medical team during lockdown orders, with a comparable proportion reporting MS symptom changes during the same time period (58%). No significant differences were noted on the BDI-II from baseline to lockdown; however, a significant difference was noted on the HADS-Depression scale from baseline to lockdown (p = 0.033), with a small increase in depression symptoms noted at the lockdown follow-up (Table 3 ).
    keywords: anxiety; covid-19; data; depression; impact; individuals; lockdown; pandemic; study
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        item: #3777 of 7819
          id: cord-301189-6sq1pfo8
      author: Zheng, Hua
       title: Impact of sex and age on respiratory support and length of hospital stay among 1,792 patients with COVID-19 in Wuhan, China
        date: 2020-07-16
       words: 1109
      flesch: 38
     summary: Summary of a Report of 24 Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study English version translated by the Chinese Society of Cardiology Clinical Characteristics of Coronavirus Disease 2019 in China Disparities in Age-Specific Morbidity and Mortality from SARS-CoV-2 in China and the Republic of Korea Abnormal pulmonary function in COVID-19 patients at time of hospital discharge Guidance in an uncertain world Data are presented as median (interquartile range) or n (%) Low-flow nasal cannula oxygen therapy Low-flow mask oxygen therapy high-flow nasal cannula oxygen therapy; NIPPV, noninvasive positive pressure ventilation; IPPV, invasive positive pressure ventilation ECMO, extracorporeal membrane oxygenation. The percentage of patients who were categorised as critical on admission was higher in males and older patients.
    keywords: covid-19; patients; support
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        item: #3778 of 7819
          id: cord-301192-wif0te3w
      author: Hoffman, David A
       title: Increasing Access to Care: Telehealth During COVID-19
        date: 2020-06-16
       words: 5795
      flesch: 42
     summary: key: cord-301192-wif0te3w authors: Hoffman, David A title: Increasing Access to Care: Telehealth During COVID-19 date: 2020-06-16 journal: J Law Biosci DOI: 10.1093/jlb/lsaa043 sha: doc_id: 301192 cord_uid: wif0te3w The COVID-19 public health emergency has amplified both the potential value and the challenges with health care providers deploying telehealth solutions. Federal and state regulators have recognized this potential of telehealth and have quickly changed a variety of laws and regulations to enable health care providers to deploy solutions quickly.
    keywords: access; care; covid-19; data; emergency; patients; privacy; providers; rpm; services; telehealth; use
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        item: #3779 of 7819
          id: cord-301216-a0rkpez7
      author: Perez, Adriana
       title: Presentation of SARS-CoV-2 Infection As Cholestatic Jaundice in Two Healthy Adolescents
        date: 2020-07-23
       words: 1672
      flesch: 41
     summary: Patients described here are unique to this report and will be excluded from our registry of COVID-19 patients. Cases in the U.S Weekly Updates by Select Demographic and Geographic Characteristics Coronavirus Disease 2019 in Children -United States SARS-CoV-2 Infection in Children Epidemiology of COVID-19 Among Children in China Characteristics and Outcomes of Children With Coronavirus Disease Infection Admitted to US and Canadian Pediatric Intensive Care Units Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center's observational study Hyperinflammatory shock in children during COVID-19 pandemic Liver injury during highly pathogenic human coronavirus infections Bilirubin levels in patients with mild and severe Covid-19:
    keywords: children; covid-19; liver; patients; sars
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        item: #3780 of 7819
          id: cord-301240-18l9juk8
      author: Löffler, Christian
       title: Two immunocompromised patients with diffuse alveolar hemorrhage as a complication of severe COVID-19
        date: 2020-07-02
       words: 1364
      flesch: 32
     summary: This mode of action resembles that of vasculitic diseases and might be the explanation why DAH can be a complication of both viral infection and ANCA vasculitis or anti-GBM disease. We present two cases of immunocompromised patients with rapidly developing hypoxemic respiratory failure and evidence of DAH in the context of SARS-CoV-2 infection.
    keywords: covid-19; dah; disease; patient
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        item: #3781 of 7819
          id: cord-301264-lkfhtb1w
      author: Davahli, Mohammad Reza
       title: The Hospitality Industry in the Face of the COVID-19 Pandemic: Current Topics and Research Methods
        date: 2020-10-09
       words: 7863
      flesch: 37
     summary: To better understand the impacts of the pandemic, the study divided the world economy into three sectors of primary (including agriculture, and petroleum & oil), secondary (including manufacturing industry), and tertiary (including education, finance industry, healthcare, hospitality tourism and aviation, real estate, sports industry, information technology, and food sector). Trend analysis was also used to examine the impact of COVID-19 on the global tourism and hospitality industry and global GDP
    keywords: analysis; aspects; covid-19; covid-19 pandemic; demand; health; hospitality industry; impacts; industry; model; pandemic; papers; research; tourism
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        item: #3782 of 7819
          id: cord-301276-eer1l8vg
      author: Sehrawat, Sharvan
       title: Opinion: Does the hygiene hypothesis apply to COVID-19 susceptibility?
        date: 2020-07-09
       words: 1737
      flesch: 30
     summary: Although the efficiency of recording all cases of COVID-19 infection and its consequence varies markedly between different countries, gathering evidence supports the idea that the outcome of infection is more likely to be asymptomatic or mild in developing countries and rarely has lethal consequences. We advocate that approaches, which elevate innate immune functions, should be used to minimize the consequences of COVID-19 infection at least until effective vaccines and antiviral therapies are developed.
    keywords: consequences; covid-19; immunity; infection
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        item: #3783 of 7819
          id: cord-301281-yur5hs2h
      author: Zelek, Wioleta M.
       title: Complement Inhibition with the C5 Blocker LFG316 in Severe COVID-19
        date: 2020-11-01
       words: 1682
      flesch: 34
     summary: COVID-19 does not lead to a typical acute respiratory distress syndrome Efficacy of prone position in acute respiratory distress syndrome patients: a pathophysiology-based review Lung stress and strain during mechanical ventilation for acute respiratory distress syndrome Respiratory pathophysiology of mechanically ventilated patients with COVID-19: a cohort study Electrical impedance tomography for positive end-expiratory pressure titration in COVID-19-related acute respiratory distress syndrome Respiratory mechanics of COVID-19-versus non-COVID-19-associated acute respiratory distress syndrome Recruitability and effect of PEEP in SARS-Cov-2-associated acute respiratory distress syndrome Lung recruitability in COVID-19-associated acute respiratory distress syndrome: a single-center observational study Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Temporal changes of CT findings in 90 patients with COVID-19 pneumonia: a longitudinal study Complement, a target for therapy in inflammatory and degenerative diseases Targeting complement pathways in polytrauma-and sepsis-induced multiple-organ dysfunction Complement activation contributes to severe acute respiratory syndrome coronavirus pathogenesis Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases Explore COVID-19 IPH group; Explore COVID-19 Marseille Immunopole group. Notably, Edwards and colleagues (2) developed a clinical screening tool to identify OSA patients with low ArTH Resp based on three predictive variables obtained from standard overnight sleep studies (i.e., polysomnograms [PSGs]): 1) nadir oxygen saturation
    keywords: blockade; complement; covid-19; patients
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        item: #3784 of 7819
          id: cord-301283-5bta8woj
      author: Rosa, William E.
       title: LGBTQ+ Inclusive Palliative Care in the Context of COVID-19:Pragmatic Recommendations for Clinicians
        date: 2020-05-11
       words: 1898
      flesch: 28
     summary: Specifically, we 1) describe important health inequity and social support background pertaining to LGBTQ+ individuals and 2) provide practical, accessible strategies for palliative care clinicians for immediate implementation to ensure LGBTQ+ inclusive care to COVID-19 positive patients. In providing care to COVID-19 positive patients, palliative care clinicians should limit questions to those deemed relevant and necessary to the care of each individual.
    keywords: care; covid-19; lgbtq+; palliative
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        item: #3785 of 7819
          id: cord-301295-kthqb2fs
      author: Rajkumar, R. P.
       title: The relationship between demographic, psychosocial and health-related parameters and the impact of COVID-19: a study of twenty-four Indian regions
        date: 2020-07-30
       words: 3643
      flesch: 41
     summary: https://doi.org/10.1101/2020.07.27.20163287 doi: medRxiv preprint by the percentage of DALYs associated with this disorder; COVID-19 mortality was associated with the burden of ischemic heart disease; and COVID-19 case fatality rate was associated with the total population of each region. No significant correlations were observed between COVID-19 mortality and case fatality rates and any socioeconomic parameter.
    keywords: covid-19; health; india; license; medrxiv; preprint
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        item: #3786 of 7819
          id: cord-301297-vgijyani
      author: Khalili, Mohammad Reza
       title: Outbreak of methanol-induced optic neuropathy amid COVID-19 pandemic
        date: 2020-09-10
       words: 757
      flesch: 37
     summary: Unfortunately, some illegal providers of alcohol to the alcohol abusers took advantage of this misconception and to increase their profit during the pandemic, sold methanol alcohol instead of ethanol. Organization WH (2020) WHO Director-General's opening remarks at the media briefing on COVID-19-11 Leisure activity participation in relation to alcohol purchasing and consumption in adolescence Leisure activities, the social weekend, and alcohol use: evidence from a daily study of first-year college students Anxiety and depression symptoms and alcohol use among adolescents-a cross sectional study of Norwegian secondary school students Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Conflict of interest The authors declare that they have no conflict of interest.
    keywords: alcohol; methanol; optic
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        item: #3787 of 7819
          id: cord-301299-flb5wwzg
      author: García, Inés Suárez
       title: SARS-CoV-2 infection among healthcare workers in a hospital in Madrid, Spain
        date: 2020-07-21
       words: 3952
      flesch: 46
     summary: HCWs were stratified in three categories according to their presumed level of occupational exposure to COVID-19 cases: high risk (HCWs with usual contact with COVID-19 patients: Accident and Emergency, Internal Medicine, Intensive Care, and Pneumology Departments), moderate risk (HCWs with occasional contact with COVID-19 patients: other medical and surgical departments not included in the high or low risk groups) and low risk (including administrative workers, social workers, hospital management, and Pharmacy, Pathology, and Preventive Medicine Departments). There were no significant differences in the proportion of COVID-19 cases according to level of occupational exposure (p=0.123).
    keywords: cases; covid-19; hcws; hospital; occupational; patients; study; workers
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        item: #3788 of 7819
          id: cord-301309-qzkhi6gw
      author: Hindilerden, Fehmi
       title: Covid-19 associated autoimmune thrombotic thrombocytopenic purpura: Report of a case
        date: 2020-07-05
       words: 1215
      flesch: 46
     summary: To the best of our knowledge, this is the second case of acquired autoimmune TTP diagnosed concomitantly with Covid-19 infection. We propose that autoimmune TTP, can be a severe autoimmune complication in Covid-19 patients and should be considered in the differential diagnosis of thrombotic microangiopathies (TMA).
    keywords: autoimmune; count; covid-19; ttp
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        item: #3789 of 7819
          id: cord-301348-h21rnyww
      author: Gherghina, Ștefan Cristian
       title: Stock Market Reactions to COVID-19 Pandemic Outbreak: Quantitative Evidence from ARDL Bounds Tests and Granger Causality Analysis
        date: 2020-09-15
       words: 6423
      flesch: 56
     summary: Granger causality was employed to investigate the causalities among COVID-19 and stock market returns, as well as between pandemic measures and several commodities. Alber [85] showed that stock market return is influenced by COVID-19 cases more than deaths, as well as by aggregate measures more than new ones.
    keywords: cases; china; covid-19; deaths; index; market; model; number; run; stock; stock market; table; variables
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        item: #3790 of 7819
          id: cord-301388-p3juk2vv
      author: Yen, Muh-Yong
       title: Recommendations for protecting against and mitigating the COVID-19 pandemic in long-term care facilities
        date: 2020-04-10
       words: 3935
      flesch: 42
     summary: In compliance with eTCB, all personnel transitioning across compartments should follow strict checkpoint hand disinfection and decontamination to ensure hand hygiene and facilitates containment of contact/fomite transmission 14, 17 Specific consideration for medical care in LTCF LTCF residents tend to be older and suffer from various comorbidities. In this article we address this relative lack of attention, arguing that enhanced traffic control bundling (eTCB) can and should be adopted and implemented as a means of protecting LTCF residents and staff.
    keywords: care; control; covid-19; disinfection; facility; infection; ltcf; residents; staff
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        item: #3791 of 7819
          id: cord-301391-5dvf1mi0
      author: Islam, Md. Milon
       title: Breathing Aid Devices to Support Novel Coronavirus (COVID-19)Infected Patients
        date: 2020-08-19
       words: 4402
      flesch: 51
     summary: We described the most recent developed breathing aid devices such as oxygen therapy devices, ventilator, and CPAP throughout the review. Oxygen therapy devices [30, 31] are an appropriate solution for the COVID-19 patients, generally available in hospitals as well as ambulance.
    keywords: air; breathing; cost; covid-19; cpap; devices; oxygen; patients; support; therapy; ventilator
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        item: #3792 of 7819
          id: cord-301402-andxwyi3
      author: Ding, Benjamin Tze Keong
       title: Operating in a Pandemic: Lessons and Strategies from an Orthopaedic Unit at the Epicenter of COVID-19 in Singapore
        date: 2020-05-06
       words: 3905
      flesch: 34
     summary: When managing patients with COVID-19, double gloves are utilized to preserve PPE, and not to reduce the risk of viral transmission, such that only the outer gloves need to be changed when soiled or when managing multiple patients 19 . At an organizational level, there were dedicated isolation wards and triage areas, training and monitoring of hospital staff in infection-control procedures, strict enforcement of droplet precautions for COVID-19 patients, and minimization of staff exposure to high-risk aerosol-generating procedures.
    keywords: care; covid-19; health; infection; n95; pandemic; patients; ppe; surgery; transmission; use; workers
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        item: #3793 of 7819
          id: cord-301405-7ijaxk4v
      author: El Mouden, Zakariyaa Ait
       title: Towards Using Graph Analytics for Tracking Covid-19
        date: 2020-12-31
       words: 3767
      flesch: 50
     summary: A good communities' detection (also called graph clustering) is the optimization function with minimal value of σ ext and maximal value of σ int . Our contribution focuses on the use of machine learning algorithms to manipulate Covid-19 data; the existing approaches classifies countries according to predefined classes and using statistical data in function of time, which is a very basic classification that requires to define the classes before processing the algorithm.
    keywords: clustering; coronavirus; countries; covid-19; data; graph; nodes; novel
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        item: #3794 of 7819
          id: cord-301412-wbu3t8j8
      author: Ippolito, Edy
       title: COVID-19 and radiation induced pneumonitis: overlapping clinical features of different diseases
        date: 2020-04-14
       words: 758
      flesch: 40
     summary: Furthermore, the prognosis of cancer patients dealing with COVID-19 disease is unpaired as they are usually older with multiple comorbidities. In conclusion, even if there is still much more to learn about COVID-19 disease, in cancer patients with a history of thoracic radiotherapy treatment and a suspicion of COVID-19 disease, an extra effort should be made to differentiate COVID-19 interstitial disease from RP.
    keywords: covid-19; patients
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        item: #3795 of 7819
          id: cord-301416-rfrbgnft
      author: Kashnitsky, Ilya
       title: COVID-19 in unequally ageing European regions
        date: 2020-08-28
       words: 1294
      flesch: 38
     summary: World Dev DOI: 10.1016/j.worlddev.2020.105170 sha: doc_id: 301416 cord_uid: rfrbgnft The map presented in this brief note summarizes regional differences in population age structures between the NUTS-3 regions of Europe in the context of unequal age- and sex-specific death risks associated with the spread of the COVID-19 pandemic. Thus, we effectively introduce a summary measure of population age structures focused on the most vulnerable to the pandemic.
    keywords: age; population; structures
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        item: #3796 of 7819
          id: cord-301424-nt35k3eg
      author: Ad, Niv
       title: Cardiac Surgery in North America and COVID-19: Regional Variability in Burden and Impact
        date: 2020-07-02
       words: 2107
      flesch: 35
     summary: As a proportion of total surgical volume, there was a relative increase of coronary artery bypass grafting surgery (High +7.2% vs. Low +4.2%, p=0.550), extracorporeal membrane oxygenation (High +2.5% vs. Low 0.4%, p=0.328) and heart transplantation (High +2.7% vs. Low 0.4%, p=0.090), and decline in valvular cases (High -7.6% vs. Low -2.6%, p=0.195). As a proportion of total surgical volume, there was 159 a relative increase of coronary artery bypass grafting surgery (High +7.2% vs. Low +4.2%, 160 p=0.550), extracorporeal membrane oxygenation (High +2.5% vs. Low 0.4%, p=0.328) and 161 heart transplantation (High +2.7% vs. Low 0.4%, p=0.090), and decline in valvular cases (High -162 7.6% vs. Low -2.6%, p=0.195).
    keywords: burden; cardiac; covid-19; institutions; patients; surgery
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        item: #3797 of 7819
          id: cord-301426-i9a5g86x
      author: Bray, I.
       title: Covid-19 mortality: a multivariate ecological analysis in relation to ethnicity, population density, obesity, deprivation and pollution
        date: 2020-07-07
       words: 2016
      flesch: 41
     summary: Univariate linear regression models were fitted, along with a multiple linear regression model which estimates independent effects of the variables of interest on Covid-19 mortality rates adjusted for the other variables in the model (Table 2 ). When ethnicity, overweight/obesity, population density and PM2.5 are included in the model, then the relationship between deprivation and Covid-19 mortality rate is no longer significant.
    keywords: covid-19; mortality; population; variables
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        item: #3798 of 7819
          id: cord-301454-ayf42grs
      author: Phyu Khin, Phyu
       title: A potential therapeutic combination for treatment of COVID-19: synergistic effect of DPP4 and RAAS suppression
        date: 2020-08-14
       words: 1765
      flesch: 39
     summary: These exciting results further reinforce that the suppression of DPP4 may be useful in multifaceted ways, not only for halting the progression to the hyper-inflammatory state, but also for reducing viral infection to target cells in COVID-19 patients. The mortality of COVID-19 patients is high in men and in elderly patients with age-related diseases such as hypertension and diabetes.
    keywords: angiotensin; covid-19; patients; receptor; sars
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        item: #3799 of 7819
          id: cord-301473-k9257jaa
      author: Pernitez-Agan, S.
       title: Bibliometric Analysis of COVID-19 in the Context of Migration Health: A Study Protocol
        date: 2020-07-11
       words: 3410
      flesch: 38
     summary: In this paper, we present the protocol for a bibliometric study that aims to identify and analyze research publications on COVID-19 focusing on migration, migrants and human mobility; specifically mapping research productivity on COVID-19 in the context of migration health by author, country, institution/ organization, health theme, and migrant topic (i.e. migrant type and country coverage). It provides useful information on the growth, impact, gaps, and trends of research publications within a particular field or discipline
    keywords: analysis; covid-19; health; migrant; migration; preprint; publications; research; scopus
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        item: #3800 of 7819
          id: cord-301474-nuaq50vi
      author: Dyck, Jason R.B.
       title: The Impact of COVID-19 on Diabetes Research in Canada
        date: 2020-05-13
       words: 717
      flesch: 35
     summary: Anecdotally, these restrictions range from almost complete stoppage of research projects (with the exception of COVID-19 research) to relatively normal research activities with minor modifications to meet the standards of new workplace guidelines and social distancing restrictions. Thus, continuation of ongoing research projects involving diabetes, as well as new projects examining how diabetes affects patients with COVID-19, are essential to the health of Canadians and global populations.
    keywords: diabetes; research
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        item: #3801 of 7819
          id: cord-301476-5uc76djv
      author: Mushi, Vivian
       title: Tailoring of the ongoing water, sanitation and hygiene interventions for prevention and control of COVID-19
        date: 2020-06-16
       words: 1322
      flesch: 42
     summary: Hand hygiene practices are imperative to curb transmission of ongoing infectious diseases caused by viruses, parasites, and bacteria These include the inadequate availability of water services, lack of basic handwashing facilities, and lack of knowledge and awareness of proper hand hygiene practices such as critical moments for handwashing, proper steps of handwashing, adequate time of handwashing, and the benefits of proper handwashing [15, 16] .
    keywords: covid-19; hygiene; wash; water
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        item: #3802 of 7819
          id: cord-301480-jk8avgky
      author: Brian, Riley
       title: How COVID-19 inspired surgical residents to rethink educational programs
        date: 2020-10-21
       words: 762
      flesch: 41
     summary: key: cord-301480-jk8avgky authors: Brian, Riley; Stock, Peter; Syed, Shareef; Hirose, Kenzo; Reilly, Linda; O'Sullivan, Patricia title: How COVID-19 inspired surgical residents to rethink educational programs date: 2020-10-21 journal: Am J Surg DOI: 10.1016/j.amjsurg.2020.10.027 sha: doc_id: 301480 cord_uid: jk8avgky nan Focus group transcripts were independently reviewed by two investigators (RB and PO'S) and codes were identified using qualitative content analysis. The final identified theme was relationships between surgical residents and their patients, patients' families, and faculty.
    keywords: residents
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        item: #3803 of 7819
          id: cord-301483-dsaltzdd
      author: Hashizume, H.
       title: Eosinophilic granulomatosis with polyangiitis mimicking COVID‐19: a case report
        date: 2020-06-04
       words: 898
      flesch: 43
     summary: All rights reserved computed tomogram revealed bilateral interstitial shadows (Fig. 1) , like those frequently seen in COVID-19 cases, so a pulmonologist segregated him on suspicion of COVID-19. The patient's complete response to steroid therapy, which usually causes deterioration in COVID-19 cases, supports our diagnosis.
    keywords: case; covid-19; range
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        item: #3804 of 7819
          id: cord-301493-32l52q3s
      author: Hill, Jason B.
       title: Frequency of venous thromboembolism in 6513 patients with COVID-19: a retrospective study
        date: 2020-11-02
       words: 3232
      flesch: 40
     summary: Although our overall rate of VTE in hospitalized patients was low, half of our cases occurred in patients who were receiving effective VTE prophylaxis prior to their VTE. Is the recommendation to use high-dose heparin for thromboprophylaxis justified? VTE incidence and risk factors in patients with severe sepsis and septic shock Thromboprophylaxis in the intensive care unit: focus on medical-surgical patients Pulmonary embolism in patients with COVID-19 Thrombosis in hospitalized patients with COVID-19 in a New York City health system Postdischarge venous thromboembolism following hospital admission with COVID-19 High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study
    keywords: covid-19; hospital; patients; prophylaxis; risk; vte
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        item: #3805 of 7819
          id: cord-301511-r7k8ufqx
      author: Issitt, Richard W
       title: Children with COVID-19 at a specialist centre: initial experience and outcome
        date: 2020-06-23
       words: 1027
      flesch: 40
     summary: It should also be noted that since vulnerable children might be shielded, the pattern of presentation reported might not be representative of a non-shielded situation, and additional epidemiological studies are required. These data show the characteristics and outcomes of children presenting to a specialist children's hospital with clinical features of COVID-19 disease and positive testing, and confirm that some children with SARS-CoV-2 might have severe disease with requirement for intensive care admission.
    keywords: children; covid-19; patients
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        item: #3806 of 7819
          id: cord-301514-yo2ebphy
      author: Holten, John
       title: The Radiology Resident Experience at a Large Tertiary Care Hospital During the COVID-19 Pandemic
        date: 2020-09-29
       words: 3124
      flesch: 38
     summary: Orders for suspected COVID-19 cases were made and implemented as a special CT Viral Airborne Screening protocol designed for prioritizing cases of suspected COVID-19 patients. The COVID-19 pandemic has created hardships on us as radiology residents and healthcare providers, but has also given us the skills to adapt and rise to future challenges that will undoubtedly present themselves.
    keywords: cases; covid-19; hospital; pandemic; patients; radiology; residents
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        item: #3807 of 7819
          id: cord-301530-l7homdjj
      author: Abobaker, Anis
       title: Reply: Iron chelation may harm patients with COVID-19
        date: 2020-09-01
       words: 758
      flesch: 44
     summary: Secondly, iron chelation drugs are not only able to bind free iron but they can also remove iron from iron-containing proteins, which means that iron chelation can have an anti-ferritin effect [6] . Iron chelation may harm patients with COVID-19 date: 2020-09-01 journal: Eur J Clin Pharmacol DOI: 10.1007/s00228-020-02988-9 sha: doc_id: 301530 cord_uid: l7homdjj nan A strikingly high level of ferritin has been reported in patients with the novel coronavirus disease 2019 (COVID-19)
    keywords: ferritin; iron
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        item: #3808 of 7819
          id: cord-301547-d4wt9dqp
      author: Seng, J. J. B.
       title: Pandemic related Health literacy - A Systematic Review of literature in COVID-19, SARS and MERS pandemics
        date: 2020-05-11
       words: 5403
      flesch: 40
     summary: https://doi.org/10.1101/2020.05.07.20094227 doi: medRxiv preprint For populations at increased risk of poor clinical outcomes of infections such as the elderly, immunocompromised patients, human-immunodeficiency virus or with multiple comorbidities, they form high priority populations where the levels of pandemic health literacy should be assessed. key: cord-301547-d4wt9dqp authors: Seng, J. J. B.; Yeam, C. T.; Huang, W. C.; Tan, N. C.; Low, L. L. title: Pandemic related Health literacy - A Systematic Review of literature in COVID-19, SARS and MERS pandemics date: 2020-05-11 journal: nan DOI: 10.1101/2020.05.07.20094227 sha: doc_id: 301547 cord_uid: d4wt9dqp Background: Health literacy plays an essential role in ones ability to acquire and understand critical medical information in the COVID-19 infodemic and other pandemics.
    keywords: covid-19; health; health literacy; knowledge; license; literacy; pandemic; preprint; studies; study
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        item: #3809 of 7819
          id: cord-301590-70qmpccs
      author: Campos, António
       title: The Paradigm Shift of Ophthalmology in the COVID-19 Era
        date: 2020-09-14
       words: 3014
      flesch: 44
     summary: The manuscript management system is completely online and includes a very quick and fair peer-review system JM and HA volunteered to assist COVID-19 patients at the emergency dedicated tent and ward in the months of March, April and May 2020.We thank Anália Carmo, MD, MSc, PhD, http://orcid.org/ 0000-0002-7704-4736, from the Laboratory of Molecular Biology/Virology, Clinical Pathology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, All authors made a significant contribution to the work reported, being involved in the conception, study design, execution, acquisition of data, analysis and interpretation. We are facing a different sort of challenge now: how to accommodate the usual huge number of patients previous to the COVID-19 outbreak in the waiting rooms, while respecting the new demands from the healthcare authorities to reduce the number of waiting patients to a half or one-third.
    keywords: cov-2; covid-19; injections; number; patients; rooms; sars; visits
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        item: #3810 of 7819
          id: cord-301619-0ojayw16
      author: Adamowicz, Jan
       title: May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications ?
        date: 2020-04-22
       words: 1217
      flesch: 28
     summary: The role of dihydrotestosterone in benign prostatic hyperplasia The 5 alpha-reductase isozyme family: A review of basic biology and their role in human diseases A link between lung androgen metabolism and the emergence of mature epithelial type II cells Alveolar type II cellfibroblast interactions, synthesis and secretion of surfactant and type I collagen Gene expression profile of androgen modulated genes in the murine fetal developing lung Transdifferentiation of alveolar epithelial type II cells to type I cells involves autocrine signaling by transforming growth factor β1 through the Smad pathway Hormonal influences on lung function and response to environmental agents: Lessons from animal models of respiratory disease Androgen inactivation in human lung fibroblasts: Variations in levels of 17β-hydroxysteroid dehydrogenase type 2 and 5α-reductase activity compatible with androgen inactivation Epithelial Regeneration and Lung Stem Cells COVID-19 infection: the perspectives on immune responses May patients receiving 5 alpha-reductase inhibitors be in higher risk of COVID-19 complications This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. During alveolar fetal development and alveolar repair after inflammatory lung disease close contacts needs to be established between fibroblasts and lung epithelial cells through gaps in the basement membrane (7).
    keywords: alpha; covid-19; inhibitors; reductase
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        item: #3811 of 7819
          id: cord-301622-mn59vszt
      author: Jomah, Shahamah
       title: Clinical efficacy of antivirals against novel coronavirus (COVID-19): A review
        date: 2020-08-03
       words: 6299
      flesch: 47
     summary: However, several agents are included in Infectious Diseases Society of America (IDSA) Management Guidelines for treatment of COVID-19 patients; including antimalaria (chloroquine, hydroxychloroquine), antivirals (lopinavir/ritonavir), antibacterial (azithromycin, and immunomodulators (Tocilizumab) based on their beneficial role reported by practicing physicians or small scale clinical trials. Altogether, 19 trials reported in this study used LPV/RTN in COVID-19 patients including 2 randomized control trials [11, 17] , 5 retrospective cohort trials
    keywords: arbidol; case; covid-19; days; group; lopinavir; lpv; patients; remdesivir; rtn; study
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        item: #3812 of 7819
          id: cord-301628-m4zfib3f
      author: Lee, Kwan Yong
       title: Consensus statement on coronary intervention during the coronavirus disease 19 pandemic: from the Korean Society of Interventional Cardiology
        date: 2020-07-01
       words: 2854
      flesch: 42
     summary: We hope these guidelines help healthcare workers and cardiovascular disease patients around the world cope with the COVID-19 pandemic. There are a few things to think about when treating suspected COVID-19 patients that are different from the traditional STEMI guidelines (Fig. 3) .
    keywords: cath; covid-19; disease; emergency; lab; patients; procedure; treatment
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        item: #3813 of 7819
          id: cord-301641-epr1sct6
      author: Kumar, Durgesh
       title: Understanding the binding affinity of noscapines with protease of SARS-CoV-2 for COVID-19 using MD simulations at different temperatures
        date: 2020-05-04
       words: 4109
      flesch: 39
     summary: The outbreak of Coronavirus Disease 2019 (COVID-19)-An emerging global health threat Molecular dynamics simulation of thermo-mechanical behaviour of elastomer cross-linked via multifunctional zwitterions Risk assessment of novel coronavirus COVID-19 outbreaks outside RCSB Protein Data Bank: Sustaining a living digital data resource that enables breakthroughs in scientific research and biomedical education Identification of hot spot residues on serine-arginine protein kinase-1 by molecular dynamics simulation studies 3D QSAR, docking, molecular dynamics simulations and MM-GBSA studies of extended side chain of the antitubercular drug (6S) 2-nitro-6-f[4-(trifluoromethoxy) benzyl Molecular docking and molecular dynamics simulation studies to identify potent AURKA inhibitors: Assessing the performance of density functional theory, MM-GBSA and mass action kinetics calculations QSAR study of anti-Human African Trypanosomiasis activity for 2-phenylimidazopyridines derivatives using DFT and Lipinski's descriptors Comprehensive evaluation of the MM-GBSA method on bromodomain-inhibitor sets Crystal structure and the DFT and MEP study of 4-benzyl-2-[2-(4-fluoro-phen-yl)-2-oxoeth-yl]-6-phenyl-pyridazin-3(2H)-one The Amber Biomolecular Simulation Programs Identifying locations with possible undetected imported severe acute respiratory syndrome coronavirus 2 cases by using importation predictions Steered molecular dynamics simulation in rational drug design Molecular modeling study of checkpoint kinase 1 inhibitors by multiple docking strategies and prime/MM-GBSA calculation Psychological interventions for people affected by the COVID-19 epidemic In docking study, prepared target protein and drug molecule were loaded into ParDOCK, a web server.
    keywords: binding; complex; coronavirus; cov-2; covid-19; drug; energy; et al; protease; sars
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        item: #3814 of 7819
          id: cord-301677-b6mnn27h
      author: Soleimanian, Saeede
       title: Harnessing Memory NK Cell to Protect Against COVID-19
        date: 2020-08-20
       words: 9758
      flesch: 28
     summary: In mice, it has been initially described that cytomegalovirus infection drives adaptive features of NK Cells with altered effector function, where NK cells bearing Ly49H receptors expanded and provided stronger responses after a secondary encounter with the virus. A subset of NK cells exhibits putatively increased effector functions against viruses following pathogen-specific and immunization.
    keywords: adaptive; cells; coronavirus; cov-2; covid-19; cytokine; disease; et al; hcmv; human; immune; infection; killer; lung; memory; nk cells; patients; respiratory; responses; role; sars; virus
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        item: #3815 of 7819
          id: cord-301684-ubw91yq1
      author: Bartiromo, Marilù
       title: Threatening drug‐drug interaction in a kidney transplant patient with Coronavirus Disease 2019 (COVID‐19)
        date: 2020-04-12
       words: 1812
      flesch: 45
     summary: We immediately discontinued both antiviral therapy and tacrolimus, starting daily monitoring of tacrolimus trough levels ( Table 1 ). Among them, organ transplant patients represent a frail susceptible category due to longterm immunosuppressive therapy.
    keywords: covid-19; patient; tacrolimus; therapy; transplant
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        item: #3816 of 7819
          id: cord-301723-zz24wmv7
      author: Jotz, Geraldo Pereira
       title: Why We Need to Use and which Mask Types are Effective against the Novel Coronavirus (COVID-19)?
        date: 2020-06-23
       words: 1375
      flesch: 51
     summary: Unfortunately, MacIntyre et al evaluated the use of cloth masks in a health care facility and found that health care workers using cotton cloth masks were at increased risk of infection compared with those who wore medical masks. World Health Organization A cluster randomised trial of cloth masks compared with medical masks in healthcare workers Effect of the COVID-19 Pandemic on the Activity of Physicians Working in the Areas of Head and Neck Surgery and Otorhinolaryngology
    keywords: covid-19; masks; transmission; use
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        item: #3817 of 7819
          id: cord-301730-flv5lnv8
      author: Pandey, Anamika
       title: Natural Plant Products: A Less Focused Aspect for the COVID-19 Viral Outbreak
        date: 2020-10-15
       words: 7111
      flesch: 35
     summary: Afterward, continuous efforts have been made to screen different plant sources via in silico, in vitro, and in vivo assays for anti-viral activity towards several viruses such as parainfluenza virus type 3, respiratory syncytial virus, poliovirus type 1, herpes simplex virus (HSV), enteric coronavirus, and rotavirus (RV). Few compounds such as dihydrotanshinone isolated from the root of Salvia miltiorrhiza showed anti-viral activity against both SARS and MERS CoV by the inhibition of proteases and hindering of the viral entry, respectively (Park et al., 2012; Kim et al., 2018) .
    keywords: activity; anti; coronavirus; cov; cov-2; covid-19; drugs; et al; inhibitors; mers; plant; potential; protease; sars; trials
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        item: #3818 of 7819
          id: cord-301734-2anqedib
      author: Lazzari, Grazia
       title: Are there overlapping clinical features between thoracic radiotherapy side effects and covid-19 pneumonia? radiation pneumonitis outside the radiation ports : three case reports
        date: 2020-09-25
       words: 1805
      flesch: 34
     summary: A Comprehensive Literature Review on the Clinical Presentation, and Management of the Pandemic Coronavirus Disease 2019 (COVID-19) Chest CT for typical 2019-nCoV pneumonia: relationship to negative RT PCR testing Use of chest CT in combination with negative RT-PCR assay for the 2019 novel coronavirus but high clinical suspicion Effects of radiation therapy on the lung: radiologic appearances and differential diagnosis COVID-19 and radiation induced pneumonitis: radiation pneumonitis outside the radiation ports : three case reports date: 2020-09-25 journal: Clin Transl Radiat Oncol DOI: 10.1016/j.ctro.2020.09.007 sha: doc_id: 301734 cord_uid: 2anqedib Respiratory involvement of Covid-19 infection, presenting as a mild flu-like illness to potentially lethal acute respiratory distress syndrome is the main clinical manifestation in adults.
    keywords: covid-19; pneumonia; pneumonitis; radiation
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        item: #3819 of 7819
          id: cord-301762-g14aik1e
      author: Voutsinas, Nicholas
       title: Incidental CT findings in the lungs in COVID-19 patients presenting with abdominal pain
        date: 2020-05-28
       words: 1885
      flesch: 42
     summary: A 20-year-old male with no significant past medical history presented to the emergency department with abdominal pain, diarrhea, and bloody stool for the past day. As the pandemic continues to progress, additional symptoms related to the disease have been identified including headache, abdominal pain, flank pain, myalgia, nausea, vomiting, and diarrhea
    keywords: covid-19; pain; patients
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        item: #3820 of 7819
          id: cord-301765-q7yavza2
      author: Gomez-Arbelaez, Diego
       title: COVID-19-RELATED AORTIC THROMBOSIS: A REPORT OF FOUR CASES
        date: 2020-05-29
       words: 914
      flesch: 36
     summary: 2020 Antithrombotic Therapy, 148 and Follow-up Hypercoagulability in Patients Admitted to Intensive Care Unit for Acute Respiratory Failure Abnormal coagulation parameters are associated with poor 154 prognosis in patients with novel coronavirus pneumonia Incidence of 157 venous thromboembolism in hospitalized patients with COVID-19 Concomitant acute aortic thrombosis and 160 pulmonary embolism complicating COVID-19 pneumonia Acute thrombosis of an 163 aortic prosthetic graft in a patient with severe COVID-19 related pneumonia Anticoagulant treatment is associated with 166 decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Antibodies in Patients with Covid-19 *Anticardiolipin IgG and IgM, anti-b2-glycoprotein A REPORT OF FOUR CASES date: 2020-05-29 journal: Ann Vasc Surg DOI: 10.1016/j.avsg.2020.05.031 sha: doc_id: 301765 cord_uid: q7yavza2 COVID-19 may predispose patients to an increased risk of thrombotic complications through various pathophysiological mechanisms.
    keywords: covid-19; patients; thrombosis
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        item: #3821 of 7819
          id: cord-301771-43fl2gwp
      author: Ouassou, Hayat
       title: The Pathogenesis of Coronavirus Disease 2019 (COVID-19): Evaluation and Prevention
        date: 2020-07-10
       words: 3881
      flesch: 40
     summary: COVID-19 infection: origin, transmission, and characteristics of human coronaviruses World Health Organization, Laboratory testing for coronavirus disease 2019 (COVID-19) in suspected human cases, World Health Organization Outbreak of pneumonia of unknown etiology in Wuhan China: the mystery and the miracle Pneumonia of unknown aetiology in Wuhan, China: potential for international spread via commercial air travel Severe acute respiratory syndrome-related coronavirus: The species and its viruses -a statement of the Coronavirus Study Group Corona virus international public health emergencies: implications for radiology management Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges Coronavirus disease 2019 (COVID-19): Situation Report 61 The next big threat to global health? The last section is on administrative policies and regulations that include educating caregivers on how to dealing patients, developing policies and plans through which early recognition of acute respiratory infection potentially caused by COVID-19 virus, preventing overcrowding in public places as much as possible, ensuring that the necessary equipment for health care is provided in sufficient quantities and permanently, providing protection to quarantine areas by the authorities to reduce patients' contact with healthy people, and imposing sanctions on those who violate the provisions that have been put in place by the authorities to limit the spread of the COVID-19 virus [56] .
    keywords: 2019; china; coronavirus; covid-19; disease; health; novel; patients; sars; treatment
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        item: #3822 of 7819
          id: cord-301779-y07xjnpe
      author: Fox, Sharon E
       title: Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans
        date: 2020-05-27
       words: 3289
      flesch: 39
     summary: Autopsy can considerably contribute to our understanding of many disease processes and could provide crucial information to guide management of patients with coronavirus disease 2019 (COVID-19). Features of diffuse alveolar damage, including hyaline membranes, were present, even in patients who had not been ventilated.
    keywords: appendix; covid-19; figure; findings; infection; lungs; patients; sars
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        item: #3823 of 7819
          id: cord-301800-ssdzd43t
      author: Atal, Shubham
       title: Approval of Itolizumab for COVID-19: A Premature Decision or Need of The Hour?
        date: 2020-10-13
       words: 4516
      flesch: 40
     summary: DCGI gives Nod for Restricted Emergency Use to Itolizumab for moderate to severe COVID-19 patients ?o=rn&id=58171 &SEO=cuba-autho rizes -the-use-of-itoli zumab -in-cases -of-covid -19 Emergency use authorization Itolizumab-a humanized anti-CD6 monoclonal antibody with a better side effects profile for the treatment of psoriasis Itolizumab provides sustained remission in plaque psoriasis: a 5-year follow-up experience An anti-CD6 monoclonal antibody (Itolizumab) reduces circulating IL-6 in severe COVID-19 elderly patients A multi-centre, open label, two arm randomized, pivotal phase 2 trial to study the efficacy and safety of itolizumab in COVID-19 complications Biocon to give more data on itolizumab after use in covid-19 treatment rejected Immunological and histological evaluation of clinical samples from psoriasis patients treated with anti-CD6 itolizumab A clinical exploratory study with itolizumab, an anti-CD6 monoclonal antibody, in patients with rheumatoid arthritis Alzumab (Itolizumab) solution for iv infusion Rationale for targeting CD6 as a treatment for autoimmune diseases Safety, efficacy and pharmacokinetics of T1h, a humanized anti-CD6 monoclonal antibody, in moderate to severe chronic plaque psoriasis-results from a randomized phase II trial Efficacy and safety of itolizumab, a novel anti-CD6 monoclonal antibody, in patients with moderate to severe chronic plaque psoriasis: results of a double-blind, randomized, placebo-controlled, phase-III study Itolizumab, an anti-CD6 monoclonal antibody, as a potential treatment for COVID-19 complications IL-6 inhibitors in the treatment of serious COVID-19: a promising therapy? On the basis of the results of this phase II trial, itolizumab was granted approval for 'restricted emergency use' for this indication in COVID-19 patients in July 2020
    keywords: approval; covid-19; drug; itolizumab; patients; phase; study; treatment; trial; use
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        item: #3824 of 7819
          id: cord-301815-83qbmc7q
      author: Shabani, Mahsa
       title: Reporting, Recording and Communication of COVID-19 Cases in Workplace: Data Protection as a Moving Target
        date: 2020-04-22
       words: 1755
      flesch: 33
     summary: In the wake of COVID-19 outbreak, concerns related to lawful processing of personal information from COVID-19 cases have led various European and national Data Protection Authorities (DPAs) to develop guidelines regarding personal data protection in the context of the COVID-19 outbreak. While processing information from COVID-19 cases by public health authorities is justified on the basis of their legal mandate in preventing infectious diseases, there is diversity regarding whether employers should/may communicate COVID-19 cases to coworkers, and how far identifying information including name(s) of the positive cases should/may be disclosed.
    keywords: cases; covid-19; data; employers
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        item: #3825 of 7819
          id: cord-301828-qux5hvcw
      author: Khalifa, Ibrahim
       title: Tannins inhibit SARS‐CoV‐2 through binding with catalytic dyad residues of 3CL(pro): An in silico approach with 19 structural different hydrolysable tannins
        date: 2020-08-11
       words: 2525
      flesch: 34
     summary: Hydrolysable tannins are also measured to be valuable in eliminating the opposing effects of several chemotherapeutic stuffs as well as in extending permanency and achieving positive overall health with anticancer possible and can be utilized as a substitute cancer-drug supply (Buzzini et al., 2008; Lin et al., 2011; Aires, 2020; Jia et al., 2019; Zhu, Khalifa, Peng, & Lic, 2018) . Hydrolysable tannins, including punicalagin, punicalin, and geraniin, exerted antiviral effects toward B virus by averting the creation of cccDNA and indorsing cccDNA decline, which may aid as chief components for the expansion of novel agents to remedy HBV-infection (Liu et al., 2016) .
    keywords: 3cl; covid-19; inhibitors; pedunculagin; pro; sars; tannins
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        item: #3826 of 7819
          id: cord-301829-6yrgkx96
      author: Bhardwaj, Rashmi
       title: Data Driven Estimation of Novel COVID-19 Transmission Risks Through Hybrid Soft-Computing Techniques
        date: 2020-07-25
       words: 1970
      flesch: 46
     summary: Transmission data of the virus outbreak to atudy gov interventions [8] . It is the need of the hour to model the factors of COVID-19 transmission to minimize its spread and the extent to which it can be harmful.
    keywords: cases; coronavirus; covid-19; data; spread
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        item: #3827 of 7819
          id: cord-301833-q8jiep32
      author: Peres, Karina Colombera
       title: Body Mass Index and Prognosis of COVID-19 Infection. A Systematic Review
        date: 2020-08-14
       words: 3697
      flesch: 41
     summary: (23) described that the distribution of BMI categories in COVID-19 patients admitted to ICU care in France differed from the control patients with non-SARS-Cov-2 respiratory disease. medRxiv Targeting the adipose tissue in COVID-19 Is adipose tissue a reservoir for viral spread, immune activation, and cytokine amplification in coronavirus disease Hospitalization rates and characteristics of patients hospitalized with laboratory-confirmed coronavirus disease 2019-Covid-net, 14 states Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease Obesity and type 2 diabetes mellitus drive immune dysfunction, infection development, and sepsis mortality Complex immune dysregulation in COVID-19 patients with severe respiratory failure Role of innate and adaptive immunity in obesity-associated metabolic disease Obesity cardiomyopathy: pathogenesis and pathophysiology Oxidative stress and vascular disease in diabetes: is the dichotomization of insulin signaling still valid? Mechanisms of thrombosis in obesity
    keywords: bmi; covid-19; disease; obesity; patients; review; risk; studies
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        item: #3828 of 7819
          id: cord-301852-9nza3po0
      author: Sears, David
       title: Occupational Health: A Key to the Control of COVID-19 in Correctional Facilities
        date: 2020-07-27
       words: 1255
      flesch: 27
     summary: The authors believe that ensuring community-standard occupational health for correctional staff during COVID-19 will protect prison residents, staff, and their communities. What has been too often lost in this conversation is the need for enhanced measures to safeguard the occupational health of correctional staff in ways that are commensurate with the risk they face while carrying out their duties.
    keywords: covid-19; health; risk; staff
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        item: #3829 of 7819
          id: cord-301857-56pot8f6
      author: Zvizdic, Zlatan
       title: Decreased number of acute appendicitis cases in pediatric population during the COVID-19 pandemic: Any link?
        date: 2020-08-21
       words: 848
      flesch: 29
     summary: Some authors have adopted conservative treatment approaches for COVID-19 positive patients having surgical emergencies such as acute appendicitis (AA), particularly for non-complicated forms [7, 8] reported that 45.5% of children with AA underwent non-operative treatment in one of the COVID-19 epicenters (New York) A systematic review with meta-analysis of randomized controlled trials comparing appendectomy and non-operative management with antibiotics Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents: A Systematic Review Considerations for the outpatient practice in pediatric surgery during the novel SARS-CoV-2 pandemic The Decreasing Incidence of Acute Appendicitis During COVID-19: A Retrospective Multi-centre Study Delayed diagnosis of paediatric appendicitis during the COVID-19 pandemic Infectious causes of appendicitis Association of viral infection and appendicitis
    keywords: appendicitis; covid-19; pandemic
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        item: #3830 of 7819
          id: cord-301873-50ym0rdm
      author: García, Juan Manuel Picardo
       title: COVID-19 en residencias de mayores: una asignatura pendiente
        date: 2020-05-21
       words: 2144
      flesch: 38
     summary: Salud Pública-Seattle y el condado de King, con la ayuda de los Centros para el Control y la Prevención de Enfermedades pusieron en marcha una investigación del caso, la localización de contactos, la cuarentena de las personas expuestas, el aislamiento de los casos confirmados y sospechosos y la mejora in situ de la prevención y el control de la infección. Salud Pública-Seattle y el condado de King, con la ayuda de los Centros para el Control y la Prevención de Enfermedades pusieron en marcha una investigación del caso, la localización de contactos, la cuarentena de las personas expuestas, el aislamiento de los casos confirmados y sospechosos y la mejora in situ de la prevención y el control de la infección.
    keywords: como; con; covid-19; del; las; los; medidas; para; personal; que; residencias; residentes
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        item: #3831 of 7819
          id: cord-301900-t4y4954h
      author: Durotoye, Idayat
       title: Pertinent roles of African higher institutions in the COVID‐19 pandemic response: The University of Ilorin, Ilorin, Nigeria; An African Model
        date: 2020-05-25
       words: 1014
      flesch: 39
     summary: Weekly interviews, audio-jingles and announcements on COVID-19 preventive measures in English and local languages were aired on the far-reaching radio waves of the University radio station (Unilorin FM) within 40 miles of the University campus. First, a 3-minute in-house produced video (on COVID-19 preventive measures) was aired weekly at film shows organized for students; shared through multiple social media platforms such as WhatsApp, Facebook, and Twitter; and displayed on digital devices across the university campuses.
    keywords: community; covid-19; health; university
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        item: #3832 of 7819
          id: cord-301921-i1o18nmw
      author: Sernicola, Alvise
       title: How to Deal With Post-viral Cutaneous Eruptions in the Era of Coronavirus Infection
        date: 2020-05-12
       words: 1146
      flesch: 34
     summary: Reported skin involvement was consistent with that commonly observed during viral infections and was described as an erythematous rash in 14 patients, a urticarial rash in three patients, and a chickenpox-like vesicular rash in one subject. Shortly thereafter, in a Chinese series of seven critical COVID-19 patients, acral ischemia presenting as cyanosis of fingers and toes with blisters and gangrene was reported in all subjects and correlated to an hypercoagulative state secondary to viral infection (8) .
    keywords: disease; patients; skin
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        item: #3833 of 7819
          id: cord-301934-l0gfangp
      author: Amin, Kritika Premnath
       title: Online Gaming During the COVID-19 Pandemic in India: Strategies for Work-Life Balance
        date: 2020-07-10
       words: 2555
      flesch: 33
     summary: During the lockdown period, there was also an increase in user engagement in online gaming among those aged 25-35 years and a marginal increase in female users (Bora 2020) . To date, online gaming has played a supporting role in public health efforts to enforce effective spatial distancing during the pandemic and has been supported by the World Health Organization's collaborative campaign (#PlayApartTogether) with the online gaming industry encouraging individuals to stay at home and limit the spread of the virus (Maden 2020) .
    keywords: gaming; health; individuals; online; time
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        item: #3834 of 7819
          id: cord-301943-qdtfjdxr
      author: Javelot, H
       title: Panique et pandémie: revue de la littérature sur les liens entre le trouble panique et l'épidémie à SARS-CoV-2
        date: 2020-05-21
       words: 4744
      flesch: 37
     summary: Cette dernière est utilisée pour décrire tout à la fois un état de panique, global, non spécifié, de la population (conduisant à des qualificatifs de « panique sociale », « panique sociétale », « réactions de panique ») Plusieurs études ont démontré les effets néfastes de l'utilisation chronique de benzodiazépines à haute puissance (comme l'alprazolam) sur les résultats à court et à long terme des traitements cognitivo-comportementaux (TCC) du
    keywords: comme; cov-2; covid-19; dans; des; disorder; les; panic; panique; par; patients; respiratoire; risque; sars; sur; trouble; une
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        item: #3835 of 7819
          id: cord-301946-erzh30mt
      author: Kwak-Kim, Joanne
       title: COVID-19 and immunomodulation treatment for women with reproductive failures
        date: 2020-06-12
       words: 5611
      flesch: 27
     summary: Gonzalez et al. 2018 , Liu et al. 2018 . It is a calcineurin inhibitor that suppresses the production of IL-2 and thus, inhibits the development and proliferation of T cells (Kay et al. 1989 ).
    keywords: cells; coronavirus; covid-19; et al; immune; infection; patients; pregnancy; sars; tnf; treatment; women
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        item: #3836 of 7819
          id: cord-301947-b6nwaost
      author: Millán-Oñate, José
       title: Successful recovery of COVID-19 pneumonia in a patient from Colombia after receiving chloroquine and clarithromycin
        date: 2020-04-24
       words: 3712
      flesch: 45
     summary: Even, there is a lack of case reports of COVID-19 patients recovering from SARS-CoV-2 infection [21, 22] . In Colombia, the Ministry of Health and the Colombian Association of Infectious Diseases [38] , have considered the possible use of chloroquine for COVID-19 patients, in those hospitalized under close medical observation, as was our case.
    keywords: case; chloroquine; clinical; coronavirus; cov-2; covid-19; day; patient; sars; treatment
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        item: #3837 of 7819
          id: cord-301975-hcinajry
      author: Proaño, Christian R.
       title: On the Macroeconomic and Social Impact of the Coronavirus Pandemic in Latin America and the Developing World
        date: 2020-06-07
       words: 2017
      flesch: 35
     summary: Latin America may provide insight into the different challenges faced by developing countries and how the EU could best help those countries. First and foremost, the existing intensive care capacities, direly needed for the patients' medical treatment against COVID-19, in developing countries are dramatically behind those of advanced economies.
    keywords: countries; covid-19; pandemic; region; world
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        item: #3838 of 7819
          id: cord-301983-aks5z29t
      author: Vakili, K.
       title: Critical Complications of COVID-19: A systematic Review and Meta-Analysis study
        date: 2020-06-16
       words: 3823
      flesch: 49
     summary: The most prevalent complications were acute respiratory distress syndrome (ARDS) 33.15% (95% CI: 23.35-43.73; I2=98.56%), acute cardiac injury 13.77% (95% CI: 9.66-18.45; I2=91.36%), arrhythmia 16.64% (95% CI: 9.34-25.5; I2=92.29%), heart failure 11.50% (95% CI: 3.45-22.83; I2=89.48%), and acute kidney injury (AKI) 8.40 %(95% CI: 5.15-12.31; I2=95.22%, respectively. According to our analysis, mortality rate of COVID-19 patients were 12.29% (95% CI: 6.20-19.99; I2=98.29%).
    keywords: analysis; clinical; complications; covid-19; patients; studies
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        item: #3839 of 7819
          id: cord-302067-yyw1he5j
      author: Roblyer, Darren
       title: Perspective on the increasing role of optical wearables and remote patient monitoring in the COVID-19 era and beyond
        date: 2020-10-21
       words: 3382
      flesch: 34
     summary: New optical RPM technologies may help address these secondary health consequences by increasing access to diagnosis, screening, and even treatment. Optical technologies already account for a large portion of RPM platforms, with a good potential for future growth.
    keywords: covid-19; healthcare; home; monitoring; pandemic; rpm; technologies; telehealth; wearables
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        item: #3840 of 7819
          id: cord-302081-l9whadpi
      author: Yasin, El-Wajeh
       title: Opening Pandora’s box: surgical tracheostomy in mechanically ventilated COVID-19 patients
        date: 2020-07-09
       words: 1211
      flesch: 46
     summary: Our hospital has seen an increase in demand for open surgical tracheostomies in COVID-19 patients admitted to the ICU. These reports suggest that a significant proportion of COVID-19 patients are being successfully weaned and extubated between day 5 and day 10, and patients requiring longer mechanical ventilation often have poorer overall prognosis.
    keywords: covid-19; patients; risk; tracheostomy
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        item: #3841 of 7819
          id: cord-302113-xqmvix1o
      author: Aacharya, Ramesh Prasad
       title: Ethical dimensions of stigma and discrimination in Nepal during COVID-19 pandemic
        date: 2020-05-27
       words: 1483
      flesch: 44
     summary: Ethical issues in the national context of Nepal during the pandemic COVID-19 particularly after the public health measures in relation to stigma and discrimination to health care professionals and patients are discussed. Incidents have been reported from various parts of the country including Sindhuli, Kathmandu and Dang districts that health care professionals have been forced to leave their rented accommodation due to their profession.
    keywords: care; covid-19; health; patients
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        item: #3842 of 7819
          id: cord-302115-r39ser2c
      author: Matricardi, Paolo Maria
       title: The first, holistic immunological model of COVID‐19: implications for prevention, diagnosis, and public health measures
        date: 2020-05-02
       words: 3743
      flesch: 37
     summary: medRxiv preprint 2020 Minimum infective dose of the major human respiratory and enteric viruses transmitted through food and the environment SARS-CoV-2 viral load and the severity of COVID-19 Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data SARS-CoV-2 viral load in upper respiratory specimens of infected patients Chest CT Findings in Cases from the Cruise Ship Diamond Princess Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for Accepted Article Among them, hospital doctors frequently exposed to COVID-19 patients are, unfortunately, highly represented.
    keywords: article; copyright; coronavirus; cov-2; covid-19; patients; pneumonia; respiratory; rights; sars
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        item: #3843 of 7819
          id: cord-302127-1abupl36
      author: Vokó, Zoltán
       title: The effect of social distance measures on COVID-19 epidemics in Europe: an interrupted time series analysis
        date: 2020-06-11
       words: 3200
      flesch: 33
     summary: key: cord-302127-1abupl36 authors: Vokó, Zoltán; Pitter, János György title: The effect of social distance measures on COVID-19 epidemics in Europe: an interrupted time series analysis date: 2020-06-11 journal: GeroScience DOI: 10.1007/s11357-020-00205-0 sha: doc_id: 302127 cord_uid: 1abupl36 Following the introduction of unprecedented “stay-at-home” national policies, the COVID-19 pandemic recently started declining in Europe. Our results allow for moderate optimism related to the gradual lifting of social distance measures in the general population, and call for specific attention to the protection of focal micro-societies enriching high-risk elderly subjects, including nursing homes and chronic care facilities.
    keywords: control; countries; covid-19; data; epidemic; european; social; time
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        item: #3844 of 7819
          id: cord-302131-w10y5sf9
      author: Barrocas, Albert
       title: Ethical Framework for Nutrition Support Resource Allocation During Shortages: Lessons From COVID‐19
        date: 2020-06-03
       words: 3754
      flesch: 41
     summary: Nutrition support professionals should also be involved in the process of scarce nutrition support resource allocation. The authors provide suggestions for management of nutrition support resources and how multidisciplinary bioethics or triage committees can help direct decisions.
    keywords: allocation; covid-19; decisions; healthcare; nutrition; pandemic; patients; resources; support
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        item: #3845 of 7819
          id: cord-302159-exexcag6
      author: Wei, Yanqiu
       title: Analysis of 2019 novel coronavirus infection and clinical characteristics of outpatients: An epidemiological study from a fever clinic in Wuhan, China
        date: 2020-06-16
       words: 3059
      flesch: 43
     summary: In terms of age distribution, the average age for the diagnosed COVID-19 patients was 53 years (±14.8 years), while the average age for nucleic acid negative patients was 49 years (±13.0 years), which was significantly younger than that of COVID-19 patients (P < 0.01). Among all 936 visitors, 460 of them conducted routine blood tests, and 309 were COVID-19 patients, while the rests were nucleic acid negative patients.
    keywords: acid; covid-19; fever; patients; sars; wuhan
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        item: #3846 of 7819
          id: cord-302163-0jav84zw
      author: Anastassopoulou, Cleo
       title: Human genetic factors associated with susceptibility to SARS-CoV-2 infection and COVID-19 disease severity
        date: 2020-10-22
       words: 4834
      flesch: 31
     summary: doi.org HLA allele frequencies and susceptibility to COVID-19 in a group of 99 Italian patients Presence of genetic variants among young men with severe COVID-19 Human TLRs and IL-1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics Control of coronavirus infection through plasmacytoid dendritic-cell-derived type I interferon Bioinformatic analysis and identification of single-stranded RNA sequences recognized by TLR7/8 in the SARS-CoV-2, SARS-CoV, and MERS-CoV genomes IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes Imbalanced host response to SARS-CoV-2 drives development of COVID-19 The X chromosome and sex-specific effects in infectious disease susceptibility Sexual dimorphism in innate immunity Sex-based differences in immune function and responses to vaccination Female predisposition to TLR7-driven autoimmunity: gene dosage and the escape from X chromosome inactivation Estrogens and autoimmune diseases Preexisting comorbidities predicting COVID-19 and mortality in the UK Biobank Community Cohort ApoE e2 and agingrelated outcomes in 379,000 UK Biobank participants APOE e4 genotype predicts severe COVID-19 in the UK Biobank community cohort Apolipoprotein E -a multifunctional protein with implications in various pathologies as a result of its structural features IFITM3 restricts the morbidity and mortality associated with influenza Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection ABO blood group and susceptibility to severe acute respiratory syndrome Relationship between the ABO blood group and the COVID-19 susceptibility Relationship between ABO blood group distribution and clinical characteristics in patients with COVID-19 Harnessing the natural anti-glycan immune response to limit the transmission of enveloped viruses such as SARS-CoV-2 Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population Elevated interleukin-6 and severe COVID-19: a meta-analysis A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation ABO blood group and von Willebrand factor: biological implications ABO blood group is a determinant of von Willebrand factor protein levels in human pulmonary endothelial cells Testing the association between blood type and COVID-19 infection, intubation, and death SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection New insights into genetic susceptibility of COVID-19: an ACE2 and TMPRSS2 polymorphism analysis TMPRSS2 and COVID-19: serendipity or opportunity for intervention? Variability in genes related to SARS-CoV-2 entry into host cells (ACE2, TMPRSS2, TMPRSS11A, ELANE, and CTSL) and its potential use in association studies SARS-CoV-2 transmission in patients with cancer at a tertiary care hospital in Wuhan, China Age-related expression of SARS-CoV-2 primining protease TMPRSS2 in the developing lung Identifying genetic variants that affect viability in large cohorts ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population Analysis of ACE2 genetic variants in 131 Italian SARS-CoV-2-positive patients COVID-19 and genetic variants of protein involved in the SARS-CoV-2 entry into the host cells A survey of genetic variants in SARS-CoV-2 interacting domains of ACE2, TMPRSS2 and TLR3/7/8 across populations Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Not applicable. The increasing availability of data from COVID-19 patient populations is allowing for potential associations to be made between specific gene loci and disease severity or susceptibility to infection.
    keywords: ace2; cov-2; covid-19; disease; infection; patients; risk; sars; severity; susceptibility; tmprss2; variants
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        item: #3847 of 7819
          id: cord-302173-536mjzy6
      author: Li, Chaowei
       title: Clinical characteristics of chronic liver disease with coronavirus disease 2019 (COVID-19): a cohort study in Wuhan, China
        date: 2020-08-28
       words: 2462
      flesch: 50
     summary: To our knowledge, the study presented here is the first to investigate clinical features and outcomes of CLD patients who have been diagnosed with COVID-19 pneumonia in a largest cohort study. To further assess prognostic significance of NLR in CLD patients with COVID-19, Kaplan-Meier survival analysis was performed to analyze overall survival (OS) (cutoff = 4.00).
    keywords: cld; covid-19; liver; mortality; patients
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        item: #3848 of 7819
          id: cord-302177-8w3ojgd4
      author: Cavayas, Yiorgos Alexandros
       title: Early experience with critically ill patients with COVID-19 in Montreal
        date: 2020-09-15
       words: 4084
      flesch: 53
     summary: A significant proportion of ICU patients likely acquired the virus in healthcare facilities, highlighting the importance of appropriate infection control policies. 11, 12 Intensive care unit admission criteria for COVID-19 patients included an oxygen requirement of [ 5 LÁmin -1 accompanied with signs of respiratory distress.
    keywords: care; cases; covid-19; hospital; icu; imv; mortality; outcomes; patients; ventilation
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        item: #3849 of 7819
          id: cord-302195-25gjbyi1
      author: Al Huraimel, Khalid
       title: SARS-CoV-2 in the environment: Modes of transmission, early detection and potential role of pollutions
        date: 2020-07-15
       words: 7091
      flesch: 36
     summary: Genetic material of SARS-CoV-2 has already been J o u r n a l P r e -p r o o f detected in wastewater samples from the Region of Valencia, Spain (Randazzo et al., 2020a) , Amsterdam Airport Schiphol, Netherlands (Lodder and de Roda Husman, 2020) , Australia (Ahmed et al., 2020) , Massachusetts, USA (Wu et al., 2020a) , France (Wurtzer et al., 2020) , Milan, Italy (La Rosa et al., 2020; Rimoldi et al., 2020) , Istanbul, Turkey (Kocamemi et al., 2020) and China (Wang et al., 2020d) . Since wastewater contains viruses excreted from infected individuals in a given wastewater treatment plant catchment population, wastewater surveillance and quantification of SARS CoV-2 can be an effective tool in estimating the number of infections in a community at an early stage of the outbreak (Ahmed et al., 2020; Mallapaty, 2020; Wu et al., 2020a) .
    keywords: air; coronavirus; covid-19; et al; evidence; pandemic; pollution; rna; sars; spread; transmission; virus; wastewater
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        item: #3850 of 7819
          id: cord-302214-ubepkkto
      author: Tang, Kuok Ho Daniel
       title: Movement control as an effective measure against Covid-19 spread in Malaysia: an overview
        date: 2020-06-13
       words: 1727
      flesch: 42
     summary: Reduction in active Covid-19 cases is evident since 5 April, with more infected individuals recovering than new Covid-19 cases (Fig. 1) . This short communication reviews articles and government announcements related to containment measures and the Movement Control Order of Malaysia, and graphically presents data pertinent to Covid-19 in Malaysia in order to show the relationship between fluctuations in Covid-19 cases and movement control.
    keywords: cases; covid-19; malaysia; mco; movement
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        item: #3851 of 7819
          id: cord-302215-sqrbj5r4
      author: Vanden Eynde, Jean Jacques
       title: COVID-19: An Update about the Discovery Clinical Trial
        date: 2020-05-14
       words: 3343
      flesch: 44
     summary: [2] , for a potential treatment, we analyzed the evolution of the number of clinical trials on April 8, April 28, and May 4. Comparison with clinical trials reported in the Chinese Clinical Trial Registry
    keywords: combination; covid-19; hydroxychloroquine; patients; remdesivir; treatment; trial
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        item: #3852 of 7819
          id: cord-302228-n5o6jfs2
      author: Lodise, Thomas P.
       title: COVID‐19: Important Therapy Considerations and Approaches in this Hour of Need
        date: 2020-05-05
       words: 1936
      flesch: 43
     summary: If data are amassed on COVID-19 patients, it is important that detailed information is collected on the outcomes associated with the treatment strategies used at our respective institutions. In conclusion, it is critically important that we ensure the most optimal therapy is delivered to COVID-19 patients in an expeditious fashion.
    keywords: covid-19; patients; sars; treatment
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        item: #3853 of 7819
          id: cord-302244-uwicyuhk
      author: Hoilat, Gilles J
       title: Percutaneous Mechanical Pulmonary Thrombectomy in a Patient With Pulmonary Embolism as a First Presentation of COVID-19
        date: 2020-08-01
       words: 1198
      flesch: 45
     summary: One retrospective study performed by Bompard et al. reported that out of 137 patients who underwent CT pulmonary angiography, 50% of them were found to have acute pulmonary embolism COVID-19-related severe hypercoagulability in patients admitted to intensive care unit for acute respiratory failure Coagulation and sepsis Clinical characteristics of coronavirus disease 2019 in China Pulmonary embolism in patients with Covid-19 pneumonia Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Pulmonary embolism in patients with COVID-19: time to change the paradigm of computed tomography The incidence of acute pulmonary embolism in a patient with COVID-19 remains unknown [6] .
    keywords: covid-19; embolism; patients; pulmonary
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        item: #3854 of 7819
          id: cord-302252-3hgy4msc
      author: Yoon, Soon Ho
       title: Chest Radiographic and CT Findings of the 2019 Novel Coronavirus Disease (COVID-19): Analysis of Nine Patients Treated in Korea
        date: 2020-02-26
       words: 2620
      flesch: 42
     summary: Time course of lung changes on chest CT during recovery from 2019 novel Coronavirus (COVID-19) pneumonia After the initial assessment of the chest radiographs, we checked whether the abnormalities on chest radiographs corresponded to abnormalities on chest CT images.
    keywords: chest; covid-19; lesions; patients; pneumonia
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        item: #3855 of 7819
          id: cord-302254-egt9qdib
      author: Amaral-Prado, Heloísa Monteiro
       title: The impact of confinement in the psychosocial behaviour due COVID-19 among members of a Brazilian university
        date: 2020-11-08
       words: 3753
      flesch: 41
     summary: For both periods analyzed, lower resilience scores lead to higher perceived stress and more accentuated depressive signs, as well as the greater resilience leads to an attenuation of the depressive signs, regardless of sex, university situation and period analyzed (Table 3) . High perceived stress can be associated with physical and psychological health problems, as well as with emotional intelligence and coping strategies employed (Enns et al., 2018) .
    keywords: covid-19; resilience; scores; signs; stress; university
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        item: #3856 of 7819
          id: cord-302271-js06pel9
      author: Primorac, Dragan
       title: Pre-season football preparation in the era of COVID-19: Croatian Football Association Model
        date: 2020-05-06
       words: 1804
      flesch: 44
     summary: Croatian Football Federation, with its Medical Committee is launching a new model of pre-season systematic examination of football players with a particular emphasis on diagnosing COVID-19. Together with Croatian Football Federation, with its Medical Committee, is launching a new model of pre-season systematic examination of football players with a particular emphasis on diagnosing COVID-19 before returning to training and competitive football.
    keywords: covid-19; football; pandemic; players; training
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        item: #3857 of 7819
          id: cord-302279-d1or6wty
      author: Kang, Chuanyuan
       title: Patients with chronic illness urgently need integrated physical and psychological care during the COVID-19 outbreak
        date: 2020-04-07
       words: 797
      flesch: 39
     summary: In this circumstance, patients with chronic diseases, such as cardiovascular diseases, active cancer, diabetes, stroke, dementia, schizophrenia, major depressive disorder, and so on, would suffer from emotional disturbance, anxiety, anger, confusion, and stigma as summarized by Brooks et al. (2020) because of sudden separation from loved ones, shortage of living supplies, the loss of freedom, and uncertainty over disease status. What's more, in this epidemic the mortality rate in elderly patients with chronic diseases is the highest.
    keywords: diseases; health; patients
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        item: #3858 of 7819
          id: cord-302304-wc40gouw
      author: Wilson, M.P.
       title: Potential implications of novel coronavirus disease (COVID-19) related gastrointestinal symptoms for abdominal imaging
        date: 2020-05-01
       words: 487
      flesch: 43
     summary: Secondly, radiographers should be prepared that the number of requests for COVID-19 related abdominal imaging may increase. Abdominal organs with high concentrations of ACE2 expression may be theoretically vulnerable to COVID-19 related infections.
    keywords: covid-19; gastrointestinal
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        item: #3859 of 7819
          id: cord-302310-16myb2n5
      author: Steffens, Ines
       title: A hundred days into the coronavirus disease (COVID-19) pandemic
        date: 2020-04-09
       words: 1847
      flesch: 42
     summary: Recently, increasing case numbers have also been seen in Africa and in Asian countries outside China that had not been affected early in the pandemic. For the first time, this has enabled updating public health practitioners, policymakers, infectious disease specialists and the general public on the numbers of pandemic cases in close to real time and with high resolution.
    keywords: cases; china; countries; covid-19; health; pandemic
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        item: #3860 of 7819
          id: cord-302316-raf5rlkq
      author: Brüssow, Harald
       title: COVID‐19: From pathogenesis models to the first drug trials
        date: 2020-06-23
       words: 6948
      flesch: 40
     summary: A Chinese study used anakinra in severe COVID-19 patients who could not receive intensive care due to overwhelming patient numbers. The Authors Isolation of SARS-CoV-2-related coronavirus from malayan pangolins Pathological findings of COVID-19 associated with acute respiratory distress syndrome Effective treatment of severe COVID-19 patients with tocilizumab Effect of convalescent plasma therapy on viral shedding and survival in COVID-19 patients SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues I thank Jacqueline Steinhauser, and Kenneth Timmis and Lutz Br€ ussow for critical reading of the manuscript.
    keywords: cell; cov-2; covid-19; disease; group; infection; interferon; lung; patients; sars; study; treatment; trial; virus
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        item: #3861 of 7819
          id: cord-302319-61zcicvo
      author: Abdelaziz, Hesham K
       title: Impact of COVID-19 pandemic on patients with ST-segment elevation myocardial infarction: Insights from a British cardiac center
        date: 2020-05-11
       words: 1617
      flesch: 46
     summary: Impact of delay to reperfusion on reperfusion success, infarct size, and clinical outcomes in patients with Stsegment elevation myocardial infarction: The INFUSE-AMI trial (INFUSEanterior myocardial infarction) Relation between door-toballoon times and mortality after primary percutaneous coronary intervention over time: a retrospective study National efforts to improve door-toballoon time results from the Door-to-Balloon Alliance Persistence of delays in presentation and treatment for patients with acute myocardial infarction: The GUSTO-I and GUSTO-III experience Fourth Universal Definition of ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial in Time Delay to Treatment and Mortality in Primary Angioplasty for Acute Myocardial Infarction: Every Minute of Delay Counts Persistence of delays in presentation and treatment for patients with acute myocardial infarction: The GUSTO-I and GUSTO-III experience When is door-to-balloon time critical? We excluded STEMI patients with unclear symptom onset or who were already in hospital during symptom onset.
    keywords: covid-19; delay; patients
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        item: #3862 of 7819
          id: cord-302321-6x7hyald
      author: Qiao, Shan
       title: Disparity in HIV Service Interruption in the Outbreak of COVID-19 in South Carolina
        date: 2020-08-27
       words: 5004
      flesch: 50
     summary: AIDS Behav DOI: 10.1007/s10461-020-03013-x sha: doc_id: 302321 cord_uid: 6x7hyald To examine HIV service interruptions during the COIVD-19 outbreak in South Carolina (SC) and identify geospatial and socioeconomic correlates of such interruptions, we collected qualitative, geospatial, and quantitative data from 27 Ryan White HIV clinics in SC in March, 2020. HIV service interruptions were categorized (none, minimal, partial, and complete interruption) and analyzed for geospatial heterogeneity.
    keywords: care; clinics; covid-19; health; hiv; interruption; office; patients; service
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        item: #3863 of 7819
          id: cord-302336-zj3oixvk
      author: Clift, Ash K
       title: Living risk prediction algorithm (QCOVID) for risk of hospital admission and mortality from coronavirus 19 in adults: national derivation and validation cohort study
        date: 2020-10-21
       words: 7354
      flesch: 38
     summary: Such linked datasets have an established track record for the development and evaluation of established clinical risk models, including those for cardiovascular disease, diabetes, and mortality. 10 Although QCOVID has been specifically designed to inform UK health policy and interventions to manage covid-19 related risks, it also has international potential, subject to local validation.
    keywords: cohort; covid-19; data; death; derivation; hospital; model; outcome; period; prediction; risk; study; time; validation
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        item: #3864 of 7819
          id: cord-302382-eifh95zm
      author: Owji, Hajar
       title: Immunotherapeutic approaches to curtail COVID-19
        date: 2020-08-21
       words: 11329
      flesch: 34
     summary: Immunology The FDA-approved gold drug Auranofin inhibits novel coronavirus (SARS-COV-2) replication and attenuates inflammation in human cells TNF-[alpha] inhibition for potential therapeutic modulation of SARS coronavirus infection Anti-inflammatory effect of thalidomide on H1N1 influenza virus-induced pulmonary injury in mice CD24 and Siglec-10 selectively repress tissue damage-induced immune responses CD24 and By contrast, a retrospective analysis of 401 patients with severe SARS revealed that corticosteroids led to reduced mortality rate and shortened hospital stay [163] .
    keywords: antibodies; antibody; cells; convalescent; coronavirus; cov-2; covid-19; cytokine; disease; human; immune; infection; inhibitors; monoclonal; patients; plasma; protein; responses; sars; syndrome; system; treatment
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        item: #3865 of 7819
          id: cord-302384-gljfslhs
      author: Al-Hanawi, Mohammed K.
       title: Knowledge, Attitude and Practice Toward COVID-19 Among the Public in the Kingdom of Saudi Arabia: A Cross-Sectional Study
        date: 2020-05-27
       words: 4546
      flesch: 49
     summary: For example, COVID-19 knowledge may increase significantly if health education programs are specifically targeted at men. For example, COVID-19 knowledge may increase significantly, if health education programs are specifically targeted at men.
    keywords: attitudes; covid-19; knowledge; practices; public; respondents; saudi; study
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        item: #3866 of 7819
          id: cord-302393-hrz3bypr
      author: Omrani, Ali S.
       title: The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation-wide cohort study
        date: 2020-10-19
       words: 4544
      flesch: 48
     summary: COVID-19 patients with significant co-morbidities or moderate to severe disease were hospitalized for inpatient management. This has stimulated discussions around rationing of critical care support for COVID-19 patients, including potentially difficult decisions to withdraw resources from one patient to provide them to another
    keywords: admission; age; cov-2; covid-19; disease; icu; patients; sars; study; years
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        item: #3867 of 7819
          id: cord-302413-7a80jff2
      author: Brown, Timothy S.
       title: The Effect of The COVID-19 Pandemic On Electively Scheduled HIP and KNEE Arthroplasty Patients in THE United States
        date: 2020-04-22
       words: 1851
      flesch: 51
     summary: 47 48 We administered a novel questionnaire to our elective hip and knee patients affected by 50 the COVID-19 pandemic. We aimed to assess the effect this had on our elective primary arthroplasty patients by distributing a specifically designed survey to patients across six institutions identified through the AAHKS Research Committee.
    keywords: anxiety; covid-19; hip; pandemic; patients
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        item: #3868 of 7819
          id: cord-302421-tvy7uo7u
      author: Brock, Rebecca L.
       title: Family Science in the Context of the COVID‐19 Pandemic: Solutions and New Directions
        date: 2020-07-14
       words: 5239
      flesch: 33
     summary: In recognition of the challenges currently faced by family scientists, we share our perspectives about conducting family research in the context of the COVID‐19 pandemic. In-person data collection might not be advisable when considering participant safety-or could be expressly prohibited at times-which limits the feasibility of certain methods commonly employed in family research (e.g., behavioral observations in controlled laboratory settings, neuropsychological testing, biological measures, in-person interventions or experimental manipulations).
    keywords: article; covid-19; data; family; health; pandemic; participants; research; stress
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        item: #3869 of 7819
          id: cord-302431-13hperkz
      author: Blanchard, Janice
       title: For us, COVID‐19 is personal
        date: 2020-05-17
       words: 1260
      flesch: 56
     summary: We must design healthcare solutions that are nuanced enough that we are able to address health disparities while improving health outcomes for all patients. For example, appropriate as they are, social distancing mandates and increased testing for COVID-19 will not yield the expected outcomes if we do not make tangible efforts to address the clear patterns in racial disparities that have emerged.
    keywords: article; communities; covid-19; health
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        item: #3870 of 7819
          id: cord-302442-jhio7mrl
      author: Chrzanowski, Wojciech
       title: Can Stem Cells Beat COVID-19: Advancing Stem Cells and Extracellular Vesicles Toward Mainstream Medicine for Lung Injuries Associated With SARS-CoV-2 Infections
        date: 2020-05-26
       words: 4167
      flesch: 25
     summary: Stem cell therapies and, more recently, their secreted extracellular vesicles (EVs), are emerging as new promising treatments, which could attenuate inflammation but also regenerate the lung damage caused by COVID-19. The original contributions presented in the study are included in the article/supplementary materials, further inquiries can be directed to the corresponding author/s. Immunomodulation by mesenchymal stem cells: a potential therapeutic strategy for type 1 diabetes Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysis 80% of NYC's Coronavirus Patients Who Are Put on Ventilators Ultimately Die, and Some Doctors Are Trying to Stop Using Them Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties Regulation and repair of the alveolar-capillary barrier in acute lung injury Extracellular vesicles, exosomes and shedding vesicles in regenerative medicine -a new paradigm for tissue repair The race for coronavirus vaccines: a graphical guide Sex-based differences in susceptibility to severe acute respiratory syndrome coronavirus infection Hydrogels with tunable stress relaxation regulate stem cell fate and activity Clinical study of mesenchymal stem cell treatment for acute respiratory distress syndrome induced by epidemic influenza A (H7N9) infection: a hint for COVID-19 treatment.
    keywords: cells; covid-19; lung; patients; sars; stem; treatment; trials
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        item: #3871 of 7819
          id: cord-302451-irb7rj7d
      author: Ssentongo, Anna E
       title: Renin–angiotensin–aldosterone system inhibitors and the risk of mortality in patients with hypertension hospitalised for COVID-19: systematic review and meta-analysis
        date: 2020-11-05
       words: 3411
      flesch: 36
     summary: We included articles that reported the rates of death in COVID-19 patients with and without taking RAAS inhibitors. Alternatively, it is hypothesised that the biological mechanisms of RAAS inhibitors may predispose COVID-19 patients to severe disease and even mortality.
    keywords: angiotensin; covid-19; inhibitors; mortality; patients; raas; studies
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        item: #3872 of 7819
          id: cord-302463-uw7xantz
      author: AĞALAR, Canan
       title: Protective measures for COVID-19 for healthcare providers and laboratory personnel
        date: 2020-04-21
       words: 3817
      flesch: 53
     summary: In order to prevent COVID-19 transmission HCP should take additional measures for contact during aerosol generating procedures (AGPs) alongside standard measures for droplets, close contact, and airborne transmission [10] . The highlights to be followed in relation to COVID-19 laboratory biosafety are specified by WHO.
    keywords: covid-19; hcp; infection; patient; ppe; procedures; risk; transmission
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        item: #3873 of 7819
          id: cord-302497-5tydrrz1
      author: Bukhari, Nadia
       title: Pharmacists at the frontline beating the COVID-19 pandemic
        date: 2020-04-20
       words: 1993
      flesch: 46
     summary: Likewise, by contributing in the prevention, preparedness and response to COVID-19 pandemic community pharmacists are delivering their role towards public health in dealing with this crisis [9] . [1] . Community pharmacists and their teams are a vital healthcare provider during the outbreak; they remain on the frontline of public health by serving as direct points of access for their patients.
    keywords: care; community; covid-19; health; pakistan; pharmacists; public
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        item: #3874 of 7819
          id: cord-302513-u9n56pnb
      author: Breitinger, Scott
       title: Key Opportunities for the COVID-19 Response to Create a Path to Sustainable Telemedicine Services
        date: 2020-10-01
       words: 1273
      flesch: 38
     summary: To maintain the progress made possible by this pandemic, some well-intended regulatory parameters of telehealth could be revised to permit greater freedom for patients, providers, health care systems and states to connect patients' needs with effective health care. During the COVID-19 era, telemedicine has been an essential method to ensure the continuation of health care services while allowing for social distancing and reducing rates of COVID-19 transmission.
    keywords: care; covid-19; health; telemedicine
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        item: #3875 of 7819
          id: cord-302517-7vmyxbe9
      author: Díaz-Pérez, Carolina
       title: Acutely altered mental status as the main clinical presentation of multiple strokes in critically ill patients with COVID-19
        date: 2020-08-17
       words: 1569
      flesch: 35
     summary: Coronavirus disease 2019 (COVID-19): a literature review Neurologic manifestations of hospitalized patients with coronavirus disease COVID-19-related severe hypercoagulability in patients admitted to intensive care unit for acute respiratory failure Mechanisms of stroke in COVID-19 Coronavirus disease 2019 and stroke: clinical manifestations and pathophysiological insights Guidelines for the diagnosis and management of disseminated intravascular coagulation. Cerebral infarction in COVID-19 patients might be associated with a hypercoagulable state related to a systemic inflammatory response.
    keywords: covid-19; data; patients
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        item: #3876 of 7819
          id: cord-302526-g70hhisy
      author: English, W.
       title: Investigation and management of suspected appendicitis during the COVID‐19 pandemic
        date: 2020-07-13
       words: 665
      flesch: 43
     summary: Br J Surg DOI: 10.1002/bjs.11787 sha: doc_id: 302526 cord_uid: g70hhisy nan The COVID-19 pandemic resulted in widespread change to the organization and delivery of emergency general surgery services in the United Kingdom 1,2 . COVID-19 pandemic: perspectives on an unfolding crisis Safe management of surgical smoke in the age of COVID-19 Updated Intercollegiate General Surgery Guidance on COVID-19 Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services Acute care surgery and post-operative COVID-19 pneumonia: a surgical and environmental challenge Multicentre observational study of performance variation in provision and outcome of emergency appendicectomy: Multicentre study of appendicectomy
    keywords: cent; patients
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        item: #3877 of 7819
          id: cord-302535-rnmftg3j
      author: van Blokland, I. V.
       title: Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility
        date: 2020-08-24
       words: 5985
      flesch: 44
     summary: For predicted COVID-19 cases, fewer symptoms of fever are reported than for cases with a positive test outcome. https://doi.org/10.1101/2020.08.21.20177246 doi: medRxiv preprint To gain insights into disease associations within the group of predicted COVID-19 cases, we explored if predicted cases report specific pre-existing conditions more often than the controls in our GWAS.
    keywords: cases; cohorts; covid-19; gwas; license; lifelines; medrxiv; model; prediction; preprint; symptoms
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        item: #3878 of 7819
          id: cord-302566-pps56i3b
      author: Kenyon, C.
       title: Intensive COVID-19 testing associated with reduced mortality - an ecological analysis of 108 countries
        date: 2020-05-30
       words: 905
      flesch: 46
     summary: The intensity of testing per 100 000 also varied considerably (median 21,970, IQR 2,735-89,095) as did the number of COVID-19 cases per 100 000 (median 1,600, IQR 340-4,760 cases/100 000). https://doi.org/10.1101/2020.05.28.20115691 doi: medRxiv preprint As COVID-19 cases, deaths and 232 fatality rates surge in Italy, underlying causes require investigation.
    keywords: capita; preprint
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        item: #3879 of 7819
          id: cord-302576-fv2ib5vc
      author: Barisione, Emanuela
       title: Fibrotic progression and radiologic correlation in matched lung samples from COVID-19 post-mortems
        date: 2020-09-28
       words: 5460
      flesch: 32
     summary: This study uses an innovative cryobiopsy approach for the post-mortem sampling of lung tissues from COVID-19 patients demonstrating the progression of fibrosis in time and correlation with computed tomography features. Following the report of endotheliitis present in COVID-19 patients [27, 28] , this feature was also actively looked for but to no avail.
    keywords: covid-19; days; disease; findings; histologic; lesions; lung; patients; patterns; phase; sars; study
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        item: #3880 of 7819
          id: cord-302595-t6yd3znu
      author: Mechessa, Desalegn Feyissa
       title: Community’s Knowledge of COVID-19 and Its Associated Factors in Mizan-Aman Town, Southwest Ethiopia, 2020
        date: 2020-08-17
       words: 2974
      flesch: 51
     summary: Additionally, the data collectors and supervisors adhered to the WHO and Ethiopian Ministry of Health guidelines on COVID-19 prevention. The findings of this study will help the responsible body organize the necessary interventional programs (education, demonstration) in order to provide up-to-date information to control COVID-19 disease.
    keywords: aman; covid-19; data; health; knowledge; mizan; study; town
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        item: #3881 of 7819
          id: cord-302625-evpw6o02
      author: Gaspar, Heloisa Amaral
       title: Home care as a safe alternative in post-acute and long-term care during COVID-19 crisis
        date: 2020-10-20
       words: 325
      flesch: 45
     summary: key: cord-302625-evpw6o02 authors: Gaspar, Heloisa Amaral; de Oliveira, Cláudio Flauzino; Jacober, Fabiana Camolesi title: Home care as a safe alternative in post-acute and long-term care during COVID-19 crisis date: 2020-10-20 journal: Einstein DOI: 10.31744/einstein_journal/2020ce6053 sha: doc_id: 302625 cord_uid: evpw6o02 nan Dear Editor, Advanced age and comorbidities are associated with increased mortality related to coronavirus disease 2019 . Our organization provided home care to 2,931 patients in the first 3 months of the pandemic and reported only 31 cases of COVID-19 (1%) and six deaths.
    keywords: care; covid-19
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        item: #3882 of 7819
          id: cord-302659-2hyiz5dr
      author: Young, H. A.
       title: Meat Processing Facilities and County Level Risk Factors for COVID-19
        date: 2020-09-26
       words: 375
      flesch: 47
     summary: Conclusions: After accounting for state differences and other county level factors, higher levels of employment in meat processing facilities increased the incidence of COVID-19 infection. The purpose was to determine if counties with higher proportions of population employed in meat processing had higher incidence of COVID-19 infection after accounting for other population level risk factors.
    keywords: covid-19
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        item: #3883 of 7819
          id: cord-302667-ei151qpd
      author: Sekar, Raghul
       title: Challenges Faced by an Otolaryngology Resident During Covid-19 Pandemic: An Indian Perspective
        date: 2020-09-01
       words: 1567
      flesch: 47
     summary: They shuffle between working with COVID positive patients and returning to treat non-COVID patients in their respective department following a period of quarantine. COVID-19 being primarily a respiratory disease, has tremendous implications in otolaryngology training and patient care.
    keywords: care; covid; pandemic; patients; residents
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        item: #3884 of 7819
          id: cord-302676-aarcjyia
      author: Goldust, Mohamad
       title: Where do we stand as dermatologists in combat with COVID‐19
        date: 2020-05-22
       words: 659
      flesch: 48
     summary: key: cord-302676-aarcjyia authors: Goldust, Mohamad; Shivakumar, Swathi; Kroumpouzos, George; Murrell, Dedee F.; Mueller, Simon M.; Navarini, Alexander A. title: Where do we stand as dermatologists in combat with COVID‐19 date: 2020-05-22 journal: Dermatol Ther DOI: 10.1111/dth.13638 sha: doc_id: 302676 cord_uid: aarcjyia nan The novel corona virus disease (COVID-19 due to SARS-CoV-2) which began in Wuhan, China in late December 2019, quickly spread to involve the rest of the world within a span of few weeks. [1] [2] [3] Hygiene measures are of paramount importance to combat transmission of COVID-19 including social distancing, meticulous hand hygiene measures like frequent hand washing, avoiding touching the face and wearing masks.
    keywords: covid-19; patients; workers
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        item: #3885 of 7819
          id: cord-302684-r4ger87o
      author: Whisenant, Jennifer G.
       title: TERAVOLT: Thoracic Cancers International COVID-19 Collaboration
        date: 2020-05-16
       words: 2010
      flesch: 28
     summary: One publication noted that the use of corticosteroids, which are frequently administered to thoracic cancer patients during treatment and for symptom management, may worsen the sequelae of acute respiratory distress syndrome (ARDS) in patients with COVID-19 (Russell et al., 2020) . Many societies have provided treatment recommendations for patients with malignancies during this pandemic, thereby revisiting our standards of care for cancer patients and allowing for a better risk/benefit ratio.
    keywords: cancer; covid-19; malignancies; patients; risk; thoracic
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        item: #3886 of 7819
          id: cord-302692-hlt879ef
      author: Daniel, Michael G.
       title: Symptom Shame in the COVID-19 Era: Battling Our Instincts
        date: 2020-06-15
       words: 1083
      flesch: 51
     summary: Consequently, it is not unusual to encounter healthcare providers in offices and hospitals with upper respiratory symptoms. Optimally, healthcare providers with upper respiratory symptoms will recognize that they might have contracted COVID-19 and self-isolate.
    keywords: covid-19; healthcare; providers; work
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        item: #3887 of 7819
          id: cord-302708-wt86pp4l
      author: Bonell, Chris
       title: Harnessing behavioural science in public health campaigns to maintain ‘social distancing’ in response to the COVID-19 pandemic: key principles
        date: 2020-08-01
       words: 2220
      flesch: 36
     summary: In the absence of a vaccine, reducing transmission of the COVID-19 virus requires rapid and extensive behaviour change to enact protective behaviours 3 and 'social distancing' across whole populations. Although 'social distancing' is the current most used term, it actually refers to maintaining physical separation by reducing the number of times people come into close contact with each other across whole populations.
    keywords: behaviour; covid-19; distancing; health; messages; public
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        item: #3888 of 7819
          id: cord-302738-7gsm6fm7
      author: Guisado-Clavero, Marina
       title: Uso de aplicaciones móviles y páginas web para el diagnóstico de la COVID-19 en España
        date: 2020-09-09
       words: 1600
      flesch: 46
     summary: y la del Ministerio de Sanidad (que da servicio a Islas Canarias, Cantabria, Castilla La Mancha, Extremadura y Principado de Asturias) dirigidas a realizar un seguimiento o diagnóstico de presunción de la COVID-19 basado en un cuestionario. Se han analizado 6 aplicaciones móviles correspondientes a 5 Comunidades Autónomas y una del Ministerio de Sanidad, además de 4 test en páginas web de la Consejería de Salud de la Comunidad Autónoma correspondiente.
    keywords: con; covid-19; del; health; las; los; por; tic
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        item: #3889 of 7819
          id: cord-302756-343y63e5
      author: Thachil, J
       title: Understanding the COVID‐19 coagulopathy spectrum
        date: 2020-05-21
       words: 2230
      flesch: 37
     summary: Overt bleeding is rare in COVID-19 patients although there are patients who develop disseminated intravascular coagulation (DIC) in common with many patients who are critically unwell. All rights reserved COVID-19 COVID-19 and what pediatric rheumatologists should know: a review from a highly affected country Targeting complement pathways in polytrauma-and sepsis-induced multiple-organ dysfunction Tissue plasminogen activator (tPA) treatment for COVID-19 associated acute respiratory distress syndrome (ARDS): a case series Hypercoaguability of COVID-19 patients in Intensive Care Unit.
    keywords: article; coagulation; copyright; covid-19; patients; system
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        item: #3890 of 7819
          id: cord-302758-i5pe61h1
      author: Pier, Matthew M.
       title: Otolaryngology-related Google Search trends during the COVID-19 pandemic
        date: 2020-06-19
       words: 2416
      flesch: 45
     summary: In total, 16.6% of search terms had significant increases in relative search volume during the COVID-19 period, with the largest percentage increase for “can't smell” (124.4%, p = .006), followed by “allergies” (30.3%, p = .03), “voice pain” (26.1%, p = .008), and “ears ringing” (19.0%, p < .001). GT does not provide quantitative information on search terms.
    keywords: covid-19; google; otolaryngology; patients; search; terms
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        item: #3891 of 7819
          id: cord-302774-ekw2oxw2
      author: Lin, Gary
       title: Explaining the Bomb-Like Dynamics of COVID-19 with Modeling and the Implications for Policy
        date: 2020-04-07
       words: 4456
      flesch: 48
     summary: The explosive nature of COVID-19 disease dynamics is likely the result of large fractions of asymptomatic and mild cases leading to rapid and silent spread throughout the community. Our results suggest that models of transmission assuming a relatively lower R0 value that do not consider a large number of asymptomatic cases can result in misunderstanding of the underlying dynamics, leading to poor policy decisions and outcomes.
    keywords: cases; covid-19; disease; license; number; preprint; transmission
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        item: #3892 of 7819
          id: cord-302786-ibt7mupq
      author: Suwanwongse, Kulachanya
       title: Fatal Outcome in a Kidney-Pancreas Transplant Recipient With COVID-19
        date: 2020-06-18
       words: 2231
      flesch: 45
     summary: Coronavirus disease 2019 COVID-19 in solid organ transplant recipients: a single center case series from Spain Successful recovery of COVID-19 pneumonia in a renal transplant recipient with long-term immunosuppression Covid-19 and kidney transplantation COVID-19 in solid organ transplant recipients: initial report from the US epicenter COVID-19 in long-term liver transplant patients: preliminary experience from an Italian transplant centre in Lombardy Clinical outcomes and serologic response in solid organ transplant recipients with COVID-19: a case series from the United States Covid-19 in solid organ transplant recipients: a single center experience COVID-19 and liver transplantation: lessons learned from three reported cases Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Complex immune dysregulation in COVID-19 patients with severe respiratory failure Dysregulation of immune response in patients with coronavirus 2019 Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Evidence based management guideline for the COVID-19 pandemic -review article Reply to Coronaviruses and immunosuppressed patients. However, impaired immune functions may paradoxically protect transplant patients from the hyper-inflammatory response to SARS-CoV-2 and thus dampen the disease severity.
    keywords: covid-19; patients; recipients; sars; transplant
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        item: #3893 of 7819
          id: cord-302800-852w35od
      author: Liu, Xuebing
       title: Clinical characteristics of hospitalised patients with schizophrenia who were suspected to have coronavirus disease (COVID-19) in Hubei Province, China
        date: 2020-04-19
       words: 3605
      flesch: 42
     summary: The mean age (SD) of COVID-19 suspected patients was 43.1 (2.6). The mean age (SD) of COVID-19 suspected patients was 43.1 (2.6).
    keywords: covid-19; group; health; mental; patients; schizophrenia
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        item: #3894 of 7819
          id: cord-302806-1e99cygs
      author: Bozkurt, Banu
       title: The COVID-19 Pandemic: Clinical Information for Ophthalmologists
        date: 2020-04-29
       words: 3692
      flesch: 47
     summary: They also stated that for this reason, healthcare workers' compliance with personal protective equipment guidelines (M3G: mask, gown, gloves, and goggles/face shield) is imperative during the examination and treatment of SARS patients. In a study including 22 patients in France, COVID-19 positive patients were given 600 mg of hydroxychloroquine per day for 10 days and it was observed that virus load decreased by 50% when used alone and by up to 100% when used in combination with azithromycin. 37
    keywords: 2019; contact; coronavirus; covid-19; disease; examination; novel; patients; samples; sars
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        item: #3895 of 7819
          id: cord-302821-b9ikg0xy
      author: Gawałko, Monika
       title: COVID-19 associated atrial fibrillation: Incidence, putative mechanisms and potential clinical implications
        date: 2020-09-01
       words: 3693
      flesch: 14
     summary: (74, 75) Little data are available on the value of rhythm and rate control strategies in AF patients with COVID-19 patients. Here, we review the available evidence for prevalence and incidence of AF in patients infected with the severe acute respiratory syndromecoronavirus 2 (SARS-CoV-2) and discuss disease management approaches and potential treatment options for COVID-19 infected AF patients.
    keywords: ace2; acute; coronavirus; covid-19; disease; fibrillation; infection; patients; sars
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        item: #3896 of 7819
          id: cord-302842-idbmh1uo
      author: Raza, Ali
       title: Association between meteorological indicators and COVID-19 pandemic in Pakistan
        date: 2020-10-14
       words: 5069
      flesch: 46
     summary: The contribution of this study is (a) it first time examined the relationship between meteorological indicators and COVID-19 in Pakistan, (b) it first time examined the relationship between meteorological indicators and COVID-19 in four provinces and three administrative units in Pakistan, and (c) it used the generalized models to investigate the impact of average temperature, rainfall, and humidity on COVID-19 cases. Contrarily, Şahin (2020) reported an increase in COVID-19 cases due to a reduction in average temperature in Turkey.
    keywords: average; cases; covid-19; covid-19 cases; humidity; pakistan; temperature
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        item: #3897 of 7819
          id: cord-302864-2xnq1oq7
      author: Quartuccio, Luca
       title: Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: results from a single Italian Centre study on tocilizumab versus standard of care
        date: 2020-05-15
       words: 3186
      flesch: 43
     summary: To conclude, our study showed that TOCI treated patients COVID-19 pneumonia were at the highest risk of cytokine storm [32] . Aging (Albany NY) Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis Prediction for Progression Risk in Patients with COVID-19 Pneumonia: the CALL Score Clinical Course and Outcomes of Critically Ill Patients With SARS-CoV-2 Pneumonia in Wuhan, China: A Single-Centered, Retrospective, Observational Study Clinical Characteristics of Coronavirus Disease 2019 in China Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Risk of thrombosis in Sjögren syndrome: the open question of endothelial function immune-mediated dysregulation Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan On the alert for cytokine storm: Immunopathology in COVID-19.
    keywords: covid-19; cytokine; data; group; patients; study; toci; tocilizumab
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        item: #3898 of 7819
          id: cord-302865-4znh4pja
      author: Goldstein, Neal D.
       title: Application of state law in the public health emergency response to COVID-19: an example from Delaware in the United States
        date: 2020-09-28
       words: 3112
      flesch: 50
     summary: On 12 March 2020, Delaware's governor declared a state of emergency as a means to coordinate state agency responses to the outbreak. Application of state law in the time of public health emergencies has historic precedent in the United States and will continue to evolve as does COVID-19.
    keywords: covid-19; delaware; disease; emergency; health; public; response; state
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        item: #3899 of 7819
          id: cord-302886-5zjghwkq
      author: Ronit, Andreas
       title: Compartmental immunophenotyping in COVID-19 ARDS: A case series
        date: 2020-10-23
       words: 4612
      flesch: 41
     summary: regulatory T cells is important for resolution of acute lung injury T helper 17 cells are involved in the local and systemic inflammatory response in community-acquired pneumonia Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy Increased percentage of CD41CD251 regulatory T cells during septic shock is due to the decrease of CD41CD25-lymphocytes Altered bone marrow lymphopoiesis and interleukin-6-dependent inhibition of thymocyte differentiation contribute to thymic atrophy during Trypanosoma cruzi infection Acute endotoxin-induced thymic atrophy is characterized by intrathymic inflammatory and wound healing responses Increased TNF-alpha-induced apoptosis in lymphocytes from aged humans: changes in TNF-alpha receptor expression and activation of caspases Disruption of CTLA-4 expression on peripheral blood CD8 1 T cell enhances anti-tumor efficacy in bladder cancer Expression of lymphocyte activation surface antigens in bronchoalveolar lavage and peripheral blood cells from young healthy subjects Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome Temporal changes in cytokine/ chemokine profiles and pulmonary involvement in severe acute respiratory syndrome Persistence of lung inflammation and lung cytokines with high-resolution CT abnormalities during recovery from SARS Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients Heightened innate immune responses in the respiratory tract of COVID-19 patients Interleukin-8 (IL-8): the major neutrophil chemotactic factor in the lung Prevention of the cytokine storm in COVID-19 Thus, the marked PD1 upregulation found not only in patient blood CD8 T cells but also in CD4 T cells likely indicates a more general pronounced exhaustion in patients with COVID-19.
    keywords: ards; balf; blood; cd4; cd8; cells; covid-19; lungs; patients; study
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        item: #3900 of 7819
          id: cord-302902-34vftqt9
      author: Law, Brenda Hiu Yan
       title: Effect of COVID-19 Precautions on Neonatal Resuscitation Practice: A Balance Between Healthcare Provider Safety, Infection Control, and Effective Neonatal Care
        date: 2020-08-18
       words: 2902
      flesch: 29
     summary: Future redesign of neonatal resuscitation equipment, spaces, training, and teams could better address infection control and protection. Neonatal resuscitation team size and composition vary.
    keywords: care; covid-19; equipment; hcps; neonatal; ppe; resuscitation; team
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        item: #3901 of 7819
          id: cord-302937-3yivxfi8
      author: Robertson, Christopher T
       title: Indemnifying precaution: economic insights for regulation of a highly infectious disease
        date: 2020-05-30
       words: 5937
      flesch: 43
     summary: Part of the heterogeneity is biological-some individuals (eg younger persons and women) appear less likely to suffer harm from infection, whereas other individuals (eg older persons, men, and those with other medical conditions) face greater risk of harm if infected. 7 Suicide and suicide attempts in younger individuals dwarf the magnitude of risk from COVID-19, which makes the pandemic precautions particularly burdensome for this population, even if yielding spillover benefits for everybody else.
    keywords: costs; covid-19; disease; hazard; health; individuals; insurance; policy; precautions; quarantine; risk; taking
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        item: #3902 of 7819
          id: cord-302939-z0071rwa
      author: Erdeve, Ömer
       title: The Turkish Neonatal Society proposal for the management of COVID-19 in the neonatal intensive care unit
        date: 2020-06-19
       words: 3959
      flesch: 41
     summary: After two separate reports including 9 and 10 infants born to mothers with COVID-19 infections, the largest series of 33 infants with early-onset sepsis born to mothers wight COVID-19 has been published recently (12, 17, 18) . Pandemic 2009 influenza A(H1N1) virus illness among pregnant women in the United States Viral infections during pregnancy Novel corona virus disease (COVID-19) in pregnancy: What clinical recommendations to follow Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases Coronavirus in pregnancy and delivery: rapid review COVID-19) and Pregnancy: What obstetricians need to know Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn Special Considerations for Neonatal-Pediatric Transport-Infection Control Working Committee on Perinatal and Neonatal Management for the Prevention and Control of the 2019 Novel Coronavirus Infection National Clinical Research Center for Child Health and Disorders and Pediatric Committee of Medical Association of Chinese People's Liberation Army.
    keywords: care; coronavirus; cov-2; covid-19; delivery; medical; mother; neonatal; newborns; patient; room; sars
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        item: #3903 of 7819
          id: cord-302947-flgwxc57
      author: Kipshidze, Nicholas
       title: Targeted, Site-Specific, Delivery Vehicles of Therapeutics for COVID-19 Patients. Brief Review
        date: 2020-09-16
       words: 2143
      flesch: 26
     summary: Targeted drug delivery of these promising pharmaceuticals might prove to be more effective, enhancing the local effect while attenuating their off-target side effects. 6-10 In the following, some of the newer approaches for targeted drug delivery in COVID-19 patients are discussed.
    keywords: approach; covid-19; delivery; drug; effects; patients
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        item: #3904 of 7819
          id: cord-302987-znogutwp
      author: Nguyen, Anne X
       title: Differences in SARS-CoV-2 recommendations from major ophthalmology societies worldwide
        date: 2020-07-07
       words: 4161
      flesch: 38
     summary: Ten out of 12 major international ophthalmology societies from countries covering all six WHO regions have given recommendations regarding urgent patient care, social distancing, telemedicine and personal protective equipment when caring for ophthalmic patients during the COVID-19 pandemic. ► All major ophthalmology societies from the G7 countries in addition to Sociedad Española de Oftalmología, All India Ophthalmological Society and Ophthalmological Society of South Africa have provided valuable information regarding urgent patient care, social distancing, telemedicine and personal protective equipment for members on their websites.
    keywords: care; covid-19; guidelines; members; ophthalmologists; ophthalmology; patients; recommendations; societies; society
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        item: #3905 of 7819
          id: cord-303000-tmk2c9eh
      author: Alhaj, Ahmad Kh.
       title: Neurosurgery Residents Perspective on the COVID-19: Knowledge, Readiness, and Impact of this Pandemic.
        date: 2020-05-16
       words: 3903
      flesch: 52
     summary: Objectives This is the first study regarding the readiness of neurosurgery residents towards the COVID-19 pandemic and its impact. The aim is to identify the level of knowledge, readiness, and the impact of this virus among neurosurgery residents in different programs.
    keywords: covid-19; impact; knowledge; neurosurgery; pandemic; residents; training
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        item: #3906 of 7819
          id: cord-303017-4zx94rm6
      author: Barbieri, Antonio
       title: Can Beta-2-Adrenergic Pathway Be a New Target to Combat SARS-CoV-2 Hyperinflammatory Syndrome?—Lessons Learned From Cancer
        date: 2020-09-30
       words: 3572
      flesch: 31
     summary: An emerging target of JAK2 inhibitor Fedratinib Distinct immune response in two MERS-CoV-infected patients: Can we go from bench to bedside Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus IL-17 response mediates acute lung injury induced by the 2009 Pandemic Influenza A (H1N1) Virus Molecular mechanisms of b2-adrenergic receptor function, response, and regulation Beta-adrenergic receptors, from their discovery and characterization through their manipulation to beneficial clinical application Autoradiographic visualization of betaadrenoceptor subtypes in human lung Bidirectional role of b2-adrenergic receptor in autoimmune diseases b2-Adrenergic agonists bias TLR-2 and NOD2 activated dendritic cells towards inducing an IL-17 immune response Regulation of Differentiation and Function of Helper T Cells by Lymphocyte-Derived Catecholamines via a 1 -and b 2 -Adrenoceptors Lymphocyte-derived catecholamines induce a shift of Th1/Th2 balance toward Th2 polarization Stress-induced alterations in interferon production and class II histocompatibility antigen expression Nondegradative role of Atg5-Atg12/Atg16L1 autophagy protein complex in antiviral activity of interferon gamma Type I and Type II Interferons Inhibit the Translation of Murine Norovirus Proteins Identification of interferon-g, as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity Enhancement of mouse natural killer cell activity by type II interferon Gammainterferon is one of several direct B cell-maturing lymphokines Distinct Requirements for IFNs and STAT1 in NK Cell Function ILC1 Confer Early Host Protection at Initial Sites of Viral Infection Long acting propranolol and HSP-70 rich tumor lysate reduce tumor growth and enhance immune response against fibrosarcoma in Balb/c mice Propranolol attenuates hemorrhage and accelerates wound healing in severely burned adults Propranolol for disruptive behaviors in nursing home residents with probable or possible Alzheimer disease: A placebo-controlled study Propranolol treatment of assaultive patients with organic brain disease: A double-blind crossover, placebo-controlled study Perioperative inhibition of b-adrenergic and COX2 signaling in a clinical trial in breast cancer patients improves tumor Ki-67 expression, serum cytokine levels, and PBMCs transcriptome Propranolol Attenuates Surgical Stress-Induced Elevation of the Regulatory T Cell Response in Patients Undergoing Radical Mastectomy Perioperative COX-2 and b-Adrenergic Blockade Improves Metastatic Biomarkers in Breast Cancer Patients in a Phase-II Randomized Trial Effect of b-blockers on platelet aggregation: A systematic review and meta-analysis The effects of aspirin and nonselective beta blockade on the acute prothrombotic response to psychosocial stress in apparently healthy subjects Beta-receptor blockade decreases elevated plasma levels of factor VIII: C in patients with deep vein thrombosis Role of endothelial nitric oxide synthase (eNOS) in chronic stress-promoted tumour growth The stress hormone norepinephrine increases migration of prostate cancer cells in vitro and in vivo Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice Anti-IL6R role in treatment of COVID-19-related ARDS Propranolol and the treatment of rheumatoid arthritis The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2 Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy b-Adrenergic receptors (b-AR) regulate VEGF and IL-6 production by divergent pathways in high b-AR-expressing breast cancer cell lines Norepinephrine and adenosine-5'-triphosphate synergize in inducing IL-6 production by human dermal microvascular endothelial cells Norepinephrine upregulates VEGF, IL-8, and IL-6 expression in human melanoma tumor cell lines: Coronaviruses-drug discovery and therapeutic options The emerging novel Middle East respiratory syndrome coronavirus: The knowns and unknowns Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection Middle East Respiratory syndrome coronavirus: Another zoonotic betacoronavirus causing SARS-like disease A novel coronavirus from patients with pneumonia in China Multiple organ infection and the pathogenesis of SARS Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus.
    keywords: adrenergic; beta; blockers; cells; covid-19; il-6; patients; propranolol; response; sars
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        item: #3907 of 7819
          id: cord-303023-rwfiug2c
      author: Toombs, Jessica
       title: Pneumococcal co‐infection in Covid‐19 patients
        date: 2020-07-08
       words: 417
      flesch: 39
     summary: How do viral infections predispose patients to bacterial infections? Pneumococcal superinfection in COVID-19 patients: a series of 5 cases Low rate of bacterial co-infection in patients with COVID-19. In keeping with good medical practice, these should only be continued when there is strong clinical or microbiological evidence of bacterial infection, regardless of Covid-19 test results, and should be de-escalated once the specific organisms are identified.
    keywords: covid-19; patients
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        item: #3908 of 7819
          id: cord-303030-8unrcb1f
      author: Gaeta, Giuseppe
       title: Social distancing versus early detection and contacts tracing in epidemic management
        date: 2020-07-16
       words: 11352
      flesch: 52
     summary: SIAM ArXiv: 2003.02062 ; Data Analysis for the COVID-19 early dynamics in Northern Italy A simple SIR model with a large set of asymptomatic infectives A simple SIR model with a large set of asymptomatic infectives How to reduce epidemic peaks keeping under control the time-span of the epidemic Accurate closed-form solution of the SIR epidemic model Asymptomatic transmission, the achilles heel of current strategies to control covid-19 (Editorial) Presumed asymptomatic carrier transmission of COVID-19 Pre-and asymptomatic individuals contribute up to 80% of COVID-19 transmission Evidence supporting transmission of severe acute respiratory syndrome coronavirus 2 while presymptomatic or asymptomatic Temporal dynamics in viral shedding and transmissibility of COVID-19 The rate of underascertainment of novel coronavirus (2019-ncov) infection: estimation using japanese passengers data on evacuation flights Estimation of the asymptomatic ratio of novel coronavirus infections (COVID-19) Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the diamond princess cruise ship Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-cov2) We have considered epidemic dynamics as described by mean field models of the SIR type; more specifically, we have first considered the classical Kermack-McKendrick SIR model [1] [2]
    keywords: asymptomatic; contacts; covid; data; epidemic; infectives; model; sir; time
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        item: #3909 of 7819
          id: cord-303034-w72oeoxq
      author: Haischer, Michael H.
       title: Who is wearing a mask? Gender-, age-, and location-related differences during the COVID-19 pandemic
        date: 2020-10-15
       words: 4432
      flesch: 50
     summary: The species severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 Reducing transmission of SARS-CoV-2 A modelling framework to assess the likely effectiveness of facemasks in combination with 'lock-down' in managing the COVID-19 pandemic United States Coronavirus Info; c2020 Temporal dynamics in viral shedding and transmissibility of COVID-19 Enviromental Health Matters Initiative Face coverings for the public: Laying straw men to rest Face masks for the public during the COVID-19 crisis Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: Additionally, mask mandates are necessary to increase mask wearing among the public to a level required to mitigate the spread of COVID-19.
    keywords: age; covid-19; data; individuals; mandates; mask; public; rural; wearing
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        item: #3910 of 7819
          id: cord-303035-xfg3iczd
      author: Zhong, Yajuan
       title: Immunity and Coagulation/Fibrinolytic Processes may Reduce the Risk of Severe Illness in Pregnant Women with COVID-19
        date: 2020-10-22
       words: 3150
      flesch: 39
     summary: In this retrospective study with the clinical outcomes of COVID-19 patients, the immune 287 dysregulation was identified as a vital feature of COVID-19 patients which developed severe 288 or critical illness, and pregnant women with COVID-19 presented similar immune response 289 with non-pregnant women with severe/critical COVID-19 but rare incidence of severe or 290 critical illness. The sub-groups were categorized 179 into pregnant women with COVID-19 (n=36), age-matched non-pregnant women with 180 mild/moderate COVID-19 (n=72) and non-pregnant women with severe/critical COVID-19 181 (n=10) to analyze the biochemical characteristics.
    keywords: covid-19; illness; patients; pregnant; study; women
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        item: #3911 of 7819
          id: cord-303039-rteysj8j
      author: Liu, Ming
       title: Efficacy and Safety of Integrated Traditional Chinese and Western Medicine for Corona Virus Disease 2019 (COVID-19): a systematic review and meta-analysis
        date: 2020-05-11
       words: 3915
      flesch: 59
     summary: Some research clues on Chinese herbal medicine for SARS prevention and treatment On the rational exertion for the prescriptions and drugs of TCM in prevention and treating SARS To explore the value of Chinese medicine in the treatment of COVID-19 from the perspective of Treatment of COVID-19 by Pneumonia No.1 Prescription and Pneumonia No.2 Prescription Clinical study on 34 cases of COVID-19 treated by integrated Chinese and western medicine Clinical study on 37 cases of COVID-19 treated by integrated Chinese and western medicine Clinical observation of 49 cases of non-critical COVID -19 treated by integrated traditional Chinese and western medicine in Shanghai Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2) Traditional Chinese medicine for COVID-19 treatment Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement The methodological and reporting quality of systematic reviews from China and the USA are similar Network meta-analyses could be improved by searching more sources and by involving a librarian The reporting characteristics and methodological quality of Cochrane reviews about health policy research The Cochrane Collaboration's tool for assessing risk of bias in randomised trials The Newcastle-Ottawa Scale (NOS) for assessing the quality of non-randomised studies in metaanalysis Measuring inconsistency in meta-analyses Clinical value of glycyrrhizinate in the treatment of patients with common new coronavirus pneumonia Clinical Effect and Mechanism of Qingfei Touxie Fuzheng Recipe in the Treatment of Novel Coronavirus Pneumonia Clinical Observation of Jinhua Qinggan Granule in Treating Pneumonia Infected by New Coronavirus Observation on the clinical effect of Shufeng Jiedu Capsule combined with Arbidol Hydrochloride Capsules in the treatment of COVID-19 Retrospective Clinical Analysis on Treatment of Novel Coronavirus-infected Pneumonia with Traditional Chinese Medicine Lianhua Qingwen Analysis of the value of Shufeng Jiedu capsules combined with Abidol in the treatment of mild new type of coronary toxin pneumonia Analysis of 51 cases of new coronavirus pneumonia treated with traditional Chinese medicine Lianhua Qingwen: a multicenter retrospective study Multi-center Clinical Observation of Reyanning Mixture in Treatment of Novel Coronavirus Pneumonia Effect of integrated traditional Chinese and Western medicine on SARS: a review of clinical evidence Atheroprotective Effects and Molecular Targets of Bioactive Compounds from Traditional Chinese Medicine Recent Advances in Traditional Chinese Medicine for Kidney Disease Anti-ageing active ingredients from herbs and nutraceuticals used in traditional Chinese medicine: pharmacological mechanisms and implications for drug discovery The immunopharmaceutical effects and mechanisms of herb medicine Standardising outcomes for clinical trials and systematic reviews Adverse event: cochrane The revised consort statement for reporting randomized trials: explanation and elaboration Appendix Table 1 However, due to the low number of included studies, low quality, and inadequate methodologies, high-quality RCTs are needed to evaluate the effect of Integrated Medicine for COVID-19.
    keywords: chinese; covid-19; medicine; quality; studies; study
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        item: #3912 of 7819
          id: cord-303046-unksl7p4
      author: Pawlotsky, Jean-Michel
       title: COVID-19 and the liver-related deaths to come
        date: 2020-06-11
       words: 1904
      flesch: 24
     summary: However, the greatest effect of COVID-19 on liver diseases will be indirect and delayed, resulting from the impending global economic crisis. Patients with cirrhosis seem to be at greater risk than other individuals for severe COVID-19 and the occurrence of complications, including mortality, regardless of the aetiology COVID-19 and the liver-related deaths to come www.nature.com/nrgastro of liver disease 6, 7 .
    keywords: covid-19; disease; liver; mortality; patients
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        item: #3913 of 7819
          id: cord-303053-238eegeu
      author: Pellegrini, Marianna
       title: Changes in Weight and Nutritional Habits in Adults with Obesity during the “Lockdown” Period Caused by the COVID-19 Virus Emergency
        date: 2020-07-07
       words: 3302
      flesch: 46
     summary: In this observational retrospective study, the patients of our Obesity Unit were invited to answer to a 12-question multiple-choice questionnaire relative to weight changes, working activity, exercise, dietary habits, and conditions potentially impacting on nutritional choices. Indeed, our results were consistent; our sample size (n = 150) achieved a 91% power with a significance level (alpha) of 0.05 to evaluate the associations with weight changes.
    keywords: anxiety; changes; covid-19; depression; obesity; patients; self; weight
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        item: #3914 of 7819
          id: cord-303054-s1clwunc
      author: Velly, Lionel
       title: Guidelines: Anaesthesia in the context of COVID-19 pandemic
        date: 2020-06-05
       words: 9243
      flesch: 35
     summary: A Narrative Review Evolving status of the 2019 novel coronavirus infection: Proposal of conventional serologic assays for disease diagnosis and infection monitoring Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019 Value of Diagnostic Testing for SARS-CoV-2/COVID-19 Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study Epidemiology of COVID-19 Among Children in China Pediatric anesthetic implications of COVID-19-A review of current literature Pediatric Airway Management in COVID-19 patients -Consensus Guidelines from the Society for Pediatric Anesthesia's Pediatric Difficult Intubation Collaborative and the Canadian Pediatric Anesthesia Society Proposal for International Standardization of the Use of Lung Ultrasound for Patients With COVID-19: In addition, some peculiarities of COVID-19 patients (risk of drug interactions, worsening of the condition, etc.) are to be taken into account.
    keywords: anaesthesia; care; children; consultation; context; cov-2; covid-19; disease; health; infection; intervention; management; mask; pandemic; patient; procedure; risk; sars; surgery; type
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        item: #3915 of 7819
          id: cord-303068-g5y7fvy5
      author: Chaudhary, Farooq Ahmad
       title: Concerns, perceived impact, and preparedness of oral healthcare workers in their working environment during COVID‐19 pandemic
        date: 2020-09-20
       words: 2923
      flesch: 51
     summary: Many countries including Pakistan have developed plans and guidelines for dental care services during COVID-19 including safety and training protocols which should be a part of dental hospital infection control and PPE training sessions. Previous researches on COVID-19 infection among the HCW had focussed on the concerns, impact, and preparedness of those working in general medicine and surgery, 10, 11 and to our knowledge, there is no study on oral healthcare workers (OHCW) has been reported.
    keywords: covid-19; infection; ohcw; pandemic; risk; study
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        item: #3916 of 7819
          id: cord-303072-3whrbuq6
      author: Wong, Fui Lin
       title: Disruption of paediatric orthopaedic hospital services due to the COVID-19 pandemic in a region with minimal COVID-19 illness
        date: 2020-08-01
       words: 3539
      flesch: 39
     summary: key: cord-303072-3whrbuq6 authors: Wong, Fui Lin; Antoniou, Georgia; Williams, Nicole; Cundy, Peter J. title: Disruption of paediatric orthopaedic hospital services due to the COVID-19 pandemic in a region with minimal COVID-19 illness date: 2020-08-01 journal: J Child Orthop DOI: 10.1302/1863-2548.14.200140 sha: doc_id: 303072 cord_uid: 3whrbuq6 PURPOSE: This article aims to provide the first description of the changes in paediatric orthopaedic hospital services as a result of the COVID-19 pandemic.
    keywords: admissions; children; covid-19; emergency; hospital; orthopaedic; pandemic; patients
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        item: #3917 of 7819
          id: cord-303081-sjxrvs4p
      author: Davis, M. M.
       title: Parents' Likelihood to Vaccinate Their Children and Themselves Against COVID-19
        date: 2020-11-13
       words: 1474
      flesch: 41
     summary: In multivariable analyses, younger parents were significantly less likely than older parents to vaccinate their children and themselves against COVID-19, as were parents with high school or less education compared with parents with bachelor's degrees and non-Hispanic White parents compared with Hispanic parents (all p<.05). In multivariable analyses, younger parents were significantly less likely than older parents to vaccinate their children and themselves against COVID-19, as were parents with high school or less education compared with parents with bachelor's degrees and non-Hispanic White parents compared with Hispanic parents (all p<.05).
    keywords: children; covid-19; parents
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        item: #3918 of 7819
          id: cord-303091-jky6jlrl
      author: Cellai, Michele
       title: Characterization of prolonged COVID-19 symptoms in an outpatient telemedicine clinic
        date: 2020-09-12
       words: 1951
      flesch: 51
     summary: Due to the presence of persistent symptoms, 16 (61.5%) of patients delayed return to work at least five weeks from symptom onset, 17 (65.3%) delayed return to activity. jky6jlrl We identified patients with coronavirus disease 2019 (COVID-19) in a telemedicine clinic who requested ongoing follow-up calls 6 weeks after symptom onset.
    keywords: patients; symptoms
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        item: #3919 of 7819
          id: cord-303100-ovrzcf84
      author: Maguire, Donogh
       title: Prognostic factors in patients admitted to an urban teaching hospital with COVID-19 infection
        date: 2020-09-15
       words: 3711
      flesch: 39
     summary: WC-cpM Laboratory findings of COVID-19: a systematic review and meta-analysis Predictors of mortality in hospitalized COVID-19 patients: a systematic review and meta-analysis Foundations of Immunometabolism and Implications for Metabolic Health and Disease Acute-phase proteins and other systemic responses to inflammation A Postoperative systemic inflammation score predicts short-and long-term outcomes in patients undergoing surgery for colorectal cancer Enhanced Recovery after surgery: which components, if any, impact on the systemic inflammatory response following colorectal surgery?: a systematic review Perioperative nutrition: recommendations from the ESPEN expert group Critical care after major surgery: a systematic review of risk factors for unplanned admission National early warning score at Emergency Department triage may allow earlier identification of patients with severe sepsis and septic shock: a retrospective observational study A global clinical measure of fitness and frailty in elderly people Association of the clinical frailty scale with hospital outcomes The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients The prognostic value of the systemic inflammatory response in randomised clinical trials in cancer: A systematic review The prognostic value of systemic inflammation in patients undergoing surgery for colon cancer: comparison of composite ratios and cumulative scores Initial clinical features of suspected coronavirus disease 2019 in two emergency departments outside of Hubei Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study COVID-19: consider cytokine storm syndromes and immunosuppression Dysregulation of immune response in patients with COVID-19 in Wuhan. Keywords: COVID-19, Systemic inflammatory response (SIRS), C-reactive protein (CRP), Albumin, Peri-operative glasgow prognostic score (poGPS), Neutrophil lymphocyte ratio (NLR), 30-day mortality, Host inflammatory response Age was grouped as less than 40 years, 40-49 years, 50-59 years, 60-69 years, 70-79 years and 80 years and older.
    keywords: covid-19; infection; inflammatory; mortality; patients; response; study; years
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        item: #3920 of 7819
          id: cord-303102-ap1dzbp9
      author: Iqbal, Sajid
       title: It is time to control the worst: testing COVID-19 outbreak, energy consumption and CO(2) emission
        date: 2020-11-12
       words: 7948
      flesch: 41
     summary: The estimate of energy consumption is further classified into different proxies, such as energy consumptions (EC) are substituted with electricity consumptions (EC1) and fossil energy consumptions (EC2). It is time to control the worst: testing COVID-19 outbreak, energy consumption and CO(2) emission date: 2020-11-12 journal:
    keywords: carbon; covid-19; covid-19 outbreak; effect; emission; energy consumption; energy sector; impact; lockdown; oil; pakistan; pandemic; policy; sector; study
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        item: #3921 of 7819
          id: cord-303107-f5k686pg
      author: Yang, Yifan
       title: Globalism or Nationalism? The Paradox of Chinese Official Discourse in the Context of the COVID-19 Outbreak
        date: 2020-09-16
       words: 9122
      flesch: 36
     summary: Meanwhile, nationalism as a sentiment or consciousness of belonging to the nation is presented by in Chinese media discourse as well praising China, blaming the US and lecturing the EU when reporting the COVID-19 outbreak. At first sight, these two contradicting positions in the spectrum of Chinese national identity discourse are easily explained.
    keywords: china; chinese; community; corpora; countries; covid-19; discourse; globalism; identity; media; nationalism; news; outbreak; world
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        item: #3922 of 7819
          id: cord-303115-bks0uvvr
      author: Brown, Elizabeth A.
       title: COVID-19: Racism Is Like That
        date: 2020-10-19
       words: 1495
      flesch: 65
     summary: Racism Is Like That date: 2020-10-19 journal: Health Equity DOI: 10.1089/heq.2020.0063 sha: doc_id: 303115 cord_uid: bks0uvvr Coronavirus disease 2019 (COVID-19)'s impact has similar characteristics to racism and its effects. Now, we experience physical distancing in school districts and residential communities because of the disadvantages related to systemic racism combined with poor socioeconomic status.
    keywords: blacks; covid-19; racism
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        item: #3923 of 7819
          id: cord-303137-g2pe3ad8
      author: Moss, Emanuel
       title: High Tech, High Risk: Tech Ethics Lessons for the COVID-19 Pandemic Response
        date: 2020-10-09
       words: 5945
      flesch: 36
     summary: Machine learning applications may construct risk such that individuals can act upon it to their own advantage without addressing the social conditions that make such risks unevenly distributed, thereby presenting a false sense of risk reduction. These risks are often framed as threatening privacy, and there are various technical methods for limiting such risks for individuals, including differential privacy, encrypted computation, and decentralized computation (particularly for contact tracing and other diagnostic applications).
    keywords: applications; companies; contact; covid-19; data; learning; machine; machine learning; pandemic; risk; society; systems
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        item: #3924 of 7819
          id: cord-303183-oya0pdhw
      author: Bersanelli, Melissa
       title: COVID-19 and the newly rediscovered multidisciplinarity
        date: 2020-09-22
       words: 733
      flesch: 16
     summary: Recovery of COVID-19 acute respiratory distress syndrome with tocilizumab: successful outcome in two critically ill patients How COVID-19 affects patients receiving anticytokine and JAK inhibitors in rheumatology and dermatology Potential protective and therapeutic role of immune checkpoint inhibitors against viral infections and COVID-19 Clinical impact of COVID-19 in a single-center cohort from a prospective study on cancer patients receiving immunotherapy COVID-19 in a patient with advanced merkel cell carcinoma receiving immunotherapy Case report: use of lenzilumab and tocilizumab for the treatment of coronavirus disease 2019 COVID-19 and immunotherapy: the complex relationship! Aside from the treatment of the SARS-CoV-2 infection, primary and secondary prevention is an incredibly important concern, especially in frail populations such as those affected by cancer, hematologic malignancies, obesity, pulmonary chronic obstructive disease, cardiovascular diseases or metabolic disorders [2] [3] [4] [5] 8 ].
    keywords: covid-19; immune; immunotherapy
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        item: #3925 of 7819
          id: cord-303192-il3s8lgp
      author: Tam, Lai‐Shan
       title: Care for patients with rheumatic diseases during COVID‐19 pandemic: A position statement from APLAR
        date: 2020-05-27
       words: 1801
      flesch: 20
     summary: Rheumatologists need to be vigilant in preventing rheumatic disease patients from contracting the disease during this pandemic, especially patients with chronic lung problems (eg scleroderma with lung fibrosis) and chronic kidney disease (eg lupus nephritis) and those on high-dose glucocorticoids and immunosuppressants (Appendix 1). 6 Globally the quality of evaluation, monitoring and treatment of comorbidities in rheumatic disease patients is variable with considerable scope for improvement.
    keywords: anti; coronavirus; covid-19; disease; patients; risk; treatment
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        item: #3926 of 7819
          id: cord-303203-1kpw4ru0
      author: Guo, Jing
       title: Coping with COVID-19: Exposure to COVID-19 and Negative Impact on Livelihood Predict Elevated Mental Health Problems in Chinese Adults
        date: 2020-05-29
       words: 4493
      flesch: 45
     summary: Mental health problems were assessed with the Post-Traumatic Stress Disorders (PTSD) Checklist for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), the Center for Epidemiological Studies Depression inventory, and the Pittsburgh Sleep Quality Index. Perceived negative impact of the pandemic on livelihood showed a large effect size in predicting mental health problems (standardized beta: 0.15, 95% CI: 0.10–0.19).
    keywords: behaviors; covid-19; exposure; health; impact; livelihood; pandemic; problems
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        item: #3927 of 7819
          id: cord-303204-xaio3nx6
      author: Dami, Fabrice
       title: Lausanne medical dispatch centre’s response to COVID-19
        date: 2020-05-13
       words: 1144
      flesch: 55
     summary: Medical dispatch is the first link of the chain of survival. It is therefore essential for dispatch centres to share their experiences while the crisis is underway, similar to hospitals, so that we will all benefit from feedback.
    keywords: calls; covid-19; dispatch
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        item: #3928 of 7819
          id: cord-303216-1pbuywz6
      author: Das, Gaurav
       title: Neurological Insights of COVID-19 Pandemic
        date: 2020-04-22
       words: 2874
      flesch: 45
     summary: 5 The likeliness of COVID-19 patients to contract neurological infections can be exacerbated by secondary factors like smoking, which according to a pilot study can enhance the chances of contracting COVID-19 based neuroinfections due to the functional interactions between hACE2 and the nicotinic receptor (nAChR). So, when smokers smoke, it augments the expression of the hACE2 due to the nicotine stimulation of nAChR. 8 Hence, while performing autopsies on brains of COVID-19 patients, it would be wise to conduct smoker versus nonsmoker based analysis as this will help to shed light on smoking being an additional risk factor in COVID-19 patients along with age and already existing ailments.
    keywords: brain; cov-2; covid-19; hace2; patients; sars; virus
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        item: #3929 of 7819
          id: cord-303232-0lwmzjxz
      author: Konig, Maximilian F
       title: Targeting the catecholamine-cytokine axis to prevent SARS-CoV-2 cytokine storm syndrome
        date: 2020-04-08
       words: 1450
      flesch: 30
     summary: Emerging evidence suggests that a subset of COVID-19 is characterized by the development of a cytokine storm syndrome (CSS) that resembles cytokine release syndrome (CRS) in chimeric antigen receptor (CAR)-T cell therapy 2, 4, 5 . In 2017, Johns Hopkins University filed a patent application on the use of various drugs to prevent cytokine release syndromes, on which V.S., R.B., B.V., K.W.K., and S.Z. are listed as inventors. .
    keywords: antagonists; covid-19; cytokine; patients
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        item: #3930 of 7819
          id: cord-303234-t95z02g9
      author: Muñoz, Miguel-Angel
       title: Lessons learned from the approach to the COVID-19 pandemic in urban primary health care centres in Barcelona, Spain
        date: 2020-07-27
       words: 916
      flesch: 51
     summary: Patients identified as COVID-19 had a telephone follow-up with PC professionals every 24, 48 or 72 h, depending on their clinical status. PHC professionals took care of this population by detecting infections, recommending isolation, or referring patients to hospital if necessary.
    keywords: covid-19; patients; professionals
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        item: #3931 of 7819
          id: cord-303237-xvba5mqq
      author: Wang, L.-Y.
       title: Genetic Profiles in Pharmacogenes Indicate Personalized Drug Therapy for COVID-19
        date: 2020-03-30
       words: 4464
      flesch: 54
     summary: They could be the explanation of individual and ethnic difference for COVID-19 drug treatment. It is noteworthy that the individual difference of drug treatment is mentioned for a special in the guideline.
    keywords: covid-19; drugs; figure; license; medrxiv; mutations; perpetuity; preprint; treatment
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        item: #3932 of 7819
          id: cord-303240-tv1ta3z5
      author: Althoff, Keri N
       title: Contact tracing: Essential to the public health response and our understanding of the epidemiology of COVID-19
        date: 2020-06-11
       words: 1403
      flesch: 50
     summary: key: cord-303240-tv1ta3z5 authors: Althoff, Keri N; Coburn, Sally B; Nash, Denis title: Contact tracing: Essential to the public health response and our understanding of the epidemiology of COVID-19 date: 2020-06-11 journal: Clin Infect Dis DOI: 10.1093/cid/ciaa757 sha: doc_id: 303240 cord_uid: tv1ta3z5 nan M a n u s c r i p t As the pandemic in the US continues to evolve, data from contact tracing can continue to inform our understanding about SARS-CoV-2 transmission and guide the public health response.
    keywords: contact; covid-19; health
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        item: #3933 of 7819
          id: cord-303284-xwhxyy3d
      author: Volpicelli, Giovanni
       title: What’s new in lung ultrasound during the COVID-19 pandemic
        date: 2020-05-04
       words: 1966
      flesch: 43
     summary: Patients presenting with the pattern described in category A have little or no pulmonary involvement and are therefore unlikely to have COVID-19 disease (i.e., asymptomatic SARS-CoV-2 carriers or patients with no lung disease). Even if there are no published studies thus far, COVID-19 patients are likely at increased risk for thromboembolism [15] .
    keywords: covid-19; disease; lung; lus; patients
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        item: #3934 of 7819
          id: cord-303297-fiievwy7
      author: Oberemok, Volodymyr V.
       title: SARS-CoV-2 will continue to circulate in the human population: an opinion from the point of view of the virus-host relationship
        date: 2020-04-30
       words: 4090
      flesch: 43
     summary: The viruses can be detected in 1-10% of patients with acute respiratory tract infections, and double infections with other respiratory viruses are common High expression of the ACE2 receptor, via which COVID-19 virus enters cells using its spike glycoprotein, was identified in type II alveolar cells (AT2) of the lung
    keywords: coronavirus; cov-2; covid-19; host; human; infection; population; sars; virus; viruses
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        item: #3935 of 7819
          id: cord-303304-3jagd9o2
      author: Bellosta, Raffaello
       title: Major cardiovascular events in patients with Coronavirus Disease 2019: experience of a cardiovascular Department of Northern Italy
        date: 2020-11-06
       words: 985
      flesch: 32
     summary: Overall mortality was 38% in our early experience, which is comparable to the 37-69.4% range reported in COVID-19 cohorts with cardiovascular complications, albeit we have not seen a higher mortality rate in COVID-19 patients with pre-existing cardiovascular risk factors [4, 8, 9] . key: cord-303304-3jagd9o2 authors: Bellosta, Raffaello; Pegorer, Matteo Alberto; Bettari, Luca; Luzzani, Luca; Attisani, Luca; Fossati, Alessandro; Consoli, Letizia; Maffeo, Diego; Cuccia, Claudio; Terragnoli, Paolo; Bush, Ruth L.; Piffaretti, Gabriele title: Major cardiovascular events in patients with Coronavirus Disease 2019: experience of a cardiovascular Department of Northern Italy date: 2020-11-06 journal: Thromb Res DOI: 10.1016/j.thromres.2020.10.038 sha: doc_id: 303304 cord_uid: 3jagd9o2 • Although small with short-term data, our series reports a translational experience of a cardiovascular department facing MACE in COVID-19 patients being acute arterial events the new insight into this COVID-19 pandemic.
    keywords: covid-19; mortality; patients
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        item: #3936 of 7819
          id: cord-303330-zh8wzza5
      author: Magleby, Reed
       title: Impact of SARS-CoV-2 Viral Load on Risk of Intubation and Mortality Among Hospitalized Patients with Coronavirus Disease 2019
        date: 2020-06-30
       words: 3560
      flesch: 42
     summary: Identifying high viral load patients could also be helpful for allocating scare therapeutic interventions such as antiviral agents (e.g., remdesivir) Higher viral load was associated with increased age, comorbidities, smoking status, and recent chemotherapy.
    keywords: cov-2; covid-19; hospital; load; patients; risk; sars
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        item: #3937 of 7819
          id: cord-303331-xolksoy3
      author: Pourghasemi, Hamid Reza
       title: Assessment of the outbreak risk, mapping and infection behavior of COVID-19: Application of the autoregressive integrated-moving average (ARIMA) and polynomial models
        date: 2020-07-28
       words: 5991
      flesch: 52
     summary: This study also can aid local authorities in imposing strict social distancing measures in the regions with high outbreak risk. Sixteen effective factors were selected for spatial modelling of outbreak risk.
    keywords: cases; covid-19; distance; fars; infection; iran; mapping; model; outbreak; outbreak risk; province; risk
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        item: #3938 of 7819
          id: cord-303357-ufy8m1d1
      author: Wang, Gang
       title: The challenge and response of mental health institutions in COVID-19 pandemic: from chaos to new normal
        date: 2020-11-06
       words: 1274
      flesch: 35
     summary: Thus, there was insufficient attention to and investment in the mental diseases of the general population and those with high risk needing attention (such as medical staff in pandemic areas), and mental health services could not be provided in a timely manner. Coronavirus disease (COVID-19) Situation Report-172 The outbreak of COVID-19 coronavirus and its impact on global mental health Addressing the COVID-19 pandemic in populations with serious mental illness Progression of mental health services during the COVID-19 outbreak in China Joint International Collaboration to Combat Mental Health Challenges during the coronavirus disease 2019 pandemic Mental health in the coronavirus disease 2019 emergency -the Italian response The authors declare that they have no conflict of interest.
    keywords: health; pandemic; patients
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        item: #3939 of 7819
          id: cord-303363-uu9hb1c9
      author: Karimi, Mehran
       title: Implications of SARSr-CoV 2 infection in thalassemias: Do patients fall into the “high clinical risk” category?
        date: 2020-05-11
       words: 3276
      flesch: 31
     summary: A first step in understanding SARS pathogenesis Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) -China Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis Clinical features of patients infected with 2019 novel coronavirus in Wuhan Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Beta-thalassemia Prevalence and predictors of cardiac and liver iron overload in patients with thalassemia: A multicenter study based on real-world data A Concise Review on the Frequency, Major Risk Factors and Surveillance of Hepatocellular Carcinoma (HCC) in β-Thalassemias: Past, Present and Future Perspectives and the ICET-A Experience Early Cardiac Involvement and Risk Factors for the Development of Arrhythmia in Patients With β-Thalassemia Major Thyroid Disorders in Homozygous β-Thalassemia: Current Knowledge, Emerging Issues and Open Problems An ICET-A survey on occult and emerging endocrine complications in patients with β-thalassemia major: Conclusions and recommendations SARS-CoV-2 infection in beta thalassemia: preliminary data from the Italian experience Coronavirus Disease 2019: Coronaviruses and Blood Safety The medical concerns of patients with thalassemias at the time of COVID-19 outbreak: The personal experience and the international recommendations THE COVID-19 PANDEMIC AND HAE-MOGLOBIN DISORDERS. Green tea and chamomile, which contain the natural antioxidant, and lastly, probiotics are recommended and beneficial in thalassemia patients against viral infections (29) .
    keywords: coronavirus; covid-19; disease; immune; infection; iron; patients; risk; sars; thalassemia
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        item: #3940 of 7819
          id: cord-303384-bgvagdft
      author: Bilinska, Katarzyna
       title: Anosmia in COVID-19: A Bumpy Road to Establishing a Cellular Mechanism
        date: 2020-07-16
       words: 2182
      flesch: 43
     summary: Nevertheless, a recent study using a hamster model also showed massive infiltration of immune cells, such as macrophages, into the OE shortly after SUS cells infection. Hence, the results of the above studies suggest a scenario in which SUS cells , exposed to the external environment, are the SARS-CoV-2 primary target in the OE.
    keywords: cells; covid-19; olfactory; orns; sars
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        item: #3941 of 7819
          id: cord-303395-r0nj16l9
      author: Basirjafari, Sedighe
       title: Association of Pediatric COVID‐19 and Subarachnoid Hemorrhage
        date: 2020-08-14
       words: 341
      flesch: 39
     summary: Thus, patients with blood type O might have protection against severe COVID-19 12 . Moreover, ABO blood type might have a prognostic role in the severity of COVID-19.
    keywords: covid-19; infection
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        item: #3942 of 7819
          id: cord-303397-lbpve38s
      author: Liu, N.
       title: Coronavirus Disease 2019 (COVID-19): An Evidence Map of Medical Literature
        date: 2020-05-11
       words: 5204
      flesch: 37
     summary: COVID-19 research is only in its nascent phase, but a large volume of research articles has already been published. COVID-19 has garnered research interest faster than any other pandemic in history, possibly due to its high transmissibility 19 fuelled by global interconnectivity; there were fewer articles on SARS and MERS combined within a year after their initial outbreaks than COVID-19 articles within the first three months of its discovery.
    keywords: analysis; articles; covid-19; evidence; health; license; medrxiv; preprint; research; review
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        item: #3943 of 7819
          id: cord-303407-n7j56sci
      author: Popofsky, Stephanie
       title: Impact of Maternal SARS-CoV-2 Detection on Breastfeeding Due to Infant Separation at Birth
        date: 2020-08-10
       words: 4369
      flesch: 38
     summary: When considering the rates of mixed feeding, the overall rates of expressed breast milk were likely higher, as 14.3% of separated mothers, and 44.4% of unseparated mothers reported a mix of feeding types (breastfeeding, expressed breast milk, and formula) during hospitalization. Nevertheless, when the rate of mixed feeding for each group is compared with the same group's rate of formula feeding (81.6% of separated mothers and 27.8% of unseparated mothers), it becomes evident that separated dyads had lower rates of breastmilk expression, irrespective of formula supplementation.
    keywords: breastfeeding; cov-2; covid-19; dyads; feeding; mothers; unseparated
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        item: #3944 of 7819
          id: cord-303414-fwamdr08
      author: Oztig, Lacin Idil
       title: Human Mobility and COVID-19: A Negative Binomial Regression Analysis
        date: 2020-07-10
       words: 2596
      flesch: 53
     summary: Based on the findings of the previous literature and the current trends in the spread of COVID-19, we hypothesize that in countries in which there is a high mobility of people, the number of COVID-19 infected people are correspondingly higher. By bearing in mind the fact that there is no scientifically established relationship between immunity and the risks of contracting COVID-19 disease, we control for the percentage of elderly people in population our analysis.
    keywords: countries; covid-19; number; people; population; spread
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        item: #3945 of 7819
          id: cord-303442-5fjb6iz8
      author: Morshed, M. S.
       title: Clinical manifestations of patients with Coronavirus Disease 2019 (COVID- 19) attending at hospitals in Bangladesh
        date: 2020-08-01
       words: 1565
      flesch: 54
     summary: However, the scientific literature on clinical manifestations of COVID-19 patients from Bangladesh is virtually absent. This study will help both the clinicians and epidemiologists to understand the magnitude and clinical spectrum of COVID-19 patients in Bangladesh.
    keywords: bangladesh; covid-19; patients; preprint
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        item: #3946 of 7819
          id: cord-303453-9nsk6vdi
      author: Schlosser, Michael
       title: COVID-19 testing processes and patient protections for resumption of elective surgery
        date: 2020-07-18
       words: 1838
      flesch: 37
     summary: In total, we piloted two strategies for pre-surgical COVID-19 testing and found that neither universal testing nor testing according to a risk-based algorithm identified a substantial number of asymptomatic COVID-19+ patients. The low prevalence of COVID-19 in both strategies suggests that factors such as differences in patient population, procedure type, or local COVID-19 activity would have a small effect, if any, on the efficiency of pre-surgical testing for COVID-19.
    keywords: covid-19; patients; surgery; testing
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        item: #3947 of 7819
          id: cord-303483-wendrxee
      author: Rubin, Geoffrey D.
       title: The Role of Chest Imaging in Patient Management during the COVID-19 Pandemic: A Multinational Consensus Statement from the Fleischner Society
        date: 2020-04-07
       words: 4318
      flesch: 28
     summary: Separate ratings were obtained for COVID-19 positive patients and either COVID-19 negative patients or patients for whom COVID-19 testing is unavailable (Fig 2, Q6 & Q7) . For COVID-19 positive patients, imaging establishes baseline pulmonary status and identifies underlying cardiopulmonary abnormalities that may facilitate risk stratification for clinical worsening.
    keywords: covid-19; disease; imaging; infection; patients; risk; test; testing; transmission
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        item: #3948 of 7819
          id: cord-303489-ve1fgnyg
      author: Klabunde, Thomas
       title: How high and long will the COVID-19 wave be? A data-driven approach to model and predict the COVID-19 epidemic and the required capacity for the German health system
        date: 2020-04-17
       words: 4829
      flesch: 52
     summary: Since early April 2020 the numbers of daily new COVID-19 cases in Germany and Italy appear to be either constant with similar numbers of new infections each day or declining (see Figure 1 ), indicating that the epidemic has moved from the exponential growth phase into a linear growth phase in these countries. Based on the projected number of new COVID-19 cases we expect that the hospital capacity requirements for severe and critical cases in Germany will decline from the 2nd week of April onwards from 13,500 to ~2500 hospital beds (range 1500-4300) and from 2500 to ~500 ICU beds in early May (range 300-800).
    keywords: april; cases; covid-19; covid-19 cases; germany; growth; preprint
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        item: #3949 of 7819
          id: cord-303514-2ljmkabk
      author: Recalcati, S.
       title: Acral cutaneous lesions in the time of COVID‐19
        date: 2020-05-27
       words: 783
      flesch: 40
     summary: key: cord-303514-2ljmkabk authors: Recalcati, S.; Barbagallo, T.; Frasin, L.A.; Prestinari, F.; Cogliardi, A.; Provero, M.C.; Dainese, E.; Vanzati, A.; Fantini, F. title: Acral cutaneous lesions in the time of COVID‐19 date: 2020-05-27 journal: J Eur Acad Dermatol Venereol DOI: 10.1111/jdv.16533 sha: doc_id: 303514 cord_uid: 2ljmkabk Coronavirus disease 2019 (COVID-19) has become a pandemic condition, yet little is known about its dermatologic manifestations. The temporal relationship with the COVID-19 pandemia, the rapid outbreak and clustering of unusual skin lesions, the occurrence of familial cases in a situation of home restriction and the multiple reporting of similar cases from other affected areas in parallel with pandemic diffusion strongly support this hypothesis.
    keywords: cases; covid-19; lesions
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        item: #3950 of 7819
          id: cord-303516-1yfaxlp5
      author: Dyer, Jessica
       title: The Psychosocial Effects of the COVID-19 Pandemic on Youth Living with HIV in Western Kenya
        date: 2020-08-20
       words: 2283
      flesch: 49
     summary: Understanding the effects of the COVID-19 pandemic on ALHIV HIV care, as well as the feasibility of conducting remote research with ALHIV, can inform interventions to support this population during and after the pandemic. Lessons learned from health services adaptations during COVID-19 offer promise to optimize ALHIV care both during the COVID-19 epidemic and beyond.
    keywords: alhiv; care; covid-19; participants; study
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        item: #3951 of 7819
          id: cord-303517-8971aq02
      author: Cajamarca-Baron, Jairo
       title: SARS-CoV-2 (COVID-19) in Patients with some Degree of Immunosuppression
        date: 2020-10-16
       words: 9107
      flesch: 33
     summary: In this review, we will focus on describing the literature on SARS-COV-2 infection in patients with some degree of immunosuppression, other than rheumatological diseases, among these, cancer patients, transplant recipients, primary immunodeficiency, and HIV patients. Therefore, special recommendations should be considered for these patients, such as postponing adjuvant chemotherapy or elective surgery in people with stable cancer, especially in endemic areas, adopting stricter personal protection measures for cancer patients or cancer survivors, and considering stricter surveillance or treatment when cancer patients are infected with SARS-CoV-2.
    keywords: cancer; cases; china; coronavirus; cov-2; covid-19; disease; immunosuppression; infection; management; patients; response; results; risk; sars; transplant; treatment; use
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        item: #3952 of 7819
          id: cord-303523-m16vlv1q
      author: Ogundokun, R. O.
       title: MACHINE LEARNING PREDICTION FOR COVID 19 PANDEMIC IN INDIA
        date: 2020-05-26
       words: 3894
      flesch: 44
     summary: The results showed that COVID-19 disease can correctly be predicted. Figure of recorded COVID-19 crises as of January 2020 to April 2020 As a substitute for epidemiologic spread procedure, the study employed 3 aggregated methods SVR, NN, and LR to predict the instantaneous movement of the conveyance dynamics and generate the real-time predictions of COVID-19 disease transversely the metropolises of India.
    keywords: cases; coronavirus; covid-19; disease; india; license; prediction; preprint; regression; study
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        item: #3953 of 7819
          id: cord-303539-gimz41yb
      author: Goudouris, Ekaterini S.
       title: Laboratory diagnosis of COVID-19()
        date: 2020-08-31
       words: 3611
      flesch: 39
     summary: Laboratory tests such as complete blood count, C-reactive protein (CRP), D-dimer, clotting tests, lactic dehydrogenase (LDH), ferritin, and procalcitonin identify risk of disease with greater severity, thromboembolic complications, myocardial damage, and/or worse prognosis. The data presented suggest that the diagnosis of COVID-19 should be based on clinical manifestations, contact history, imaging tests, laboratory tests, and not only on serological tests and the search for the genetic material of the virus.
    keywords: cov-2; covid-19; diagnosis; material; sars; sensitivity; tests; virus
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        item: #3954 of 7819
          id: cord-303571-ossmgzzn
      author: Iorfa, S. K.
       title: COVID-19 knowledge, risk perception and precautionary behaviour among Nigerians: A moderated mediation approach
        date: 2020-05-26
       words: 3307
      flesch: 37
     summary: Those studies supporting the present result suggested that individual's ability to promote precautionary behaviour largely rely on perceived risk of contracting a disease, and that risk perception is a strong predictor of precautionary behaviours. Gender also predicted precautionary behaviour suggesting that females engaged in more precautionary behaviour than their male counterparts.
    keywords: behaviour; covid-19; females; gender; knowledge; perception; risk
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        item: #3955 of 7819
          id: cord-303572-5np6373x
      author: Furstenburg, Phillip P.
       title: Emergency centre reorganization in preparation to the COVID-19 pandemic: A district hospital’s dynamic adaptation response
        date: 2020-09-16
       words: 1562
      flesch: 38
     summary: The preparation included the identification of a person under investigation (PUI) room, converting short stay wards into COVID-19 isolation areas, and relocating the paediatric section to an area outside the emergency centre. The preparation included the identification of a person under investigation (PUI) room, converting short stay wards into COVID-19 isolation areas, and relocating the paediatric section to an area outside the emergency centre.
    keywords: area; covid-19; pandemic; room
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        item: #3956 of 7819
          id: cord-303585-8py6joh6
      author: Verma, Surjeet
       title: Anti-SARS-CoV Natural Products With the Potential to Inhibit SARS-CoV-2 (COVID-19)
        date: 2020-09-25
       words: 10898
      flesch: 37
     summary: RNA dependent RNA polymerase (RdRp) (nsp12) Essential protease enzyme that catalyzes the replication of RNA from the RNA template SARS-CoV SARS CoV-2 Non-structural protein 13 (NSP13)/ helicase Enhances the efficiency of viral replication and proliferation through its NTPase, duplex RNA/DNA-unwinding and RNA-capping activities SARS CoV (Shum and Tanner, 2008) concluded that the integrated use of TCM and Western medicine for SARS patients was safe and that there could be potential benefits to SARS patients using this combined treatment method. In a study by Xu et al. (2020) , biopsies were taken from the lung, liver, and heart tissue of a patient who died from a cardiac arrest associated with COVID-19.
    keywords: 3cl; activity; cells; compounds; coronavirus; cov; cov-2; covid-19; et al; infection; inhibit; inhibition; patients; plants; potential; pro; replication; sars; study; treatment; values; viral
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        item: #3957 of 7819
          id: cord-303600-96vtj89w
      author: Kapoor, Deeksha
       title: Elective Gastrointestinal Surgery in COVID Times
        date: 2020-10-22
       words: 3571
      flesch: 44
     summary: Tele-consultations were performed extensively to maintain the line of care and guide the management of surgical patients, especially those with GI cancers. The hospital, being actively involved in treating COVID patients, undertook various measures like setting up a dedicated flu clinic, the segregation of buildings into COVID and non-COVID blocks, the separation of entry/exit, and the complete isolation of the movement circuit for COVID-positive or suspected patients.
    keywords: cancer; covid; covid-19; pandemic; patients; period; procedures; surgery
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        item: #3958 of 7819
          id: cord-303601-o8uk6if2
      author: Tsay, Calvin
       title: Modeling, state estimation, and optimal control for the US COVID-19 outbreak
        date: 2020-07-01
       words: 6183
      flesch: 41
     summary: The frequency of these periods may be restricted, e.g., by including rate-of-change constraints in the optimization problem, to account for the ability of a country or local authority to intermittently enforce social distancing policies. Optimal moving horizon control policy (right) to limit peak infections to 1,400,000, with e and a underestimated by a factor of three at t = 74 , and comparison to the same situation without a moving horizon strategy (left).
    keywords: control; covid-19; distancing; model; optimization; problem; subjects; testing; time
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        item: #3959 of 7819
          id: cord-303603-4mi64bgm
      author: Martínez-Urbistondo, Diego
       title: Early Combination of Tocilizumab and Corticosteroids: An Upgrade in Anti-inflammatory Therapy for Severe Coronavirus Disease (COVID)
        date: 2020-07-04
       words: 657
      flesch: 34
     summary: In this context, the use of anti-inflammatory therapy to treat severe COVID patients has been controversial during the whole pandemics. The results of our cohort may reinforce the early administration of anti-inflammatory therapy published by Fadel et al.
    keywords: corticosteroids; patients; therapy
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        item: #3960 of 7819
          id: cord-303609-9217t0ui
      author: Baselga, María Trinidad
       title: Trombosis y COVID-19: revisión de alcance
        date: 2020-09-24
       words: 3236
      flesch: 34
     summary: Clasificamos los artículos en 3 áreas: clínica de la COVID-19, las alteraciones en los parámetros analíticos causados por el SARS-CoV-2 y los hallazgos radiológicos de estos pacientes. En los artículos que profundizaron en la clínica y hallazgos radiológicos de la COVID-19; incluimos el porcentaje de las diferentes manifestaciones clínicas, las complicaciones trombóticas; así como los hallazgos por dos técnicas de imagen más empleadas:
    keywords: artículos; complicaciones; con; cov-2; covid-19; esta; estudios; las; los; pacientes; para; por; que; relación; revisión; sars; trombosis; una
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        item: #3961 of 7819
          id: cord-303621-uipazeve
      author: Rajkumar, R. P.
       title: Genetic polymorphisms mediating behavioural and immune response to pathogens may moderate the impact of the COVID-19 pandemic: a pilot study
        date: 2020-06-04
       words: 2483
      flesch: 41
     summary: The IL-6 rs1800795 G allele was negatively correlated with COVID-19 prevalence ({rho} = -0.466, p < 0.01) and mortality ({rho} = -0.591, p<0.001) across nations. The 5-HTTLPR s allele was negatively correlated with COVID-19 mortality rates ({rho} = -0.437, p = 0.023).
    keywords: allele; covid-19; license; preprint
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        item: #3962 of 7819
          id: cord-303631-u0rzxw7o
      author: Hart, Andrew
       title: Cover Illustration: “Lockdown” mural, Bath Street, Glasgow, by the.rebel.bearUnshackling Plastic Surgery from COVID-19
        date: 2020-06-14
       words: 1336
      flesch: 24
     summary: Cancer surgery must recommence urgently, with initial supranormal throughput if delays in delivering definitive surgical care are not to be perpetuated, and the increased mortality and healthcare cost made permanent. World Bank global poverty projection Lockdown Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection Federation of Surgical Specialty Associations guidance on surgi aesthetic guidance on recommencing elective surgery
    keywords: care; covid-19; healthcare; reconstruction; surgery
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        item: #3963 of 7819
          id: cord-303651-fkdep6cp
      author: Thompson, Robin N.
       title: Key questions for modelling COVID-19 exit strategies
        date: 2020-08-12
       words: 11573
      flesch: 35
     summary: Adjusting COVID-19 deaths to account for reporting delay Using mobility to estimate the transmission intensity of COVID-19 in Italy: a subnational analysis with future scenarios A note on generation times in epidemic models Serial interval of SARS-CoV-2 was shortened over time by nonpharmaceutical interventions Using information theory to optimise epidemic models for real-time prediction and estimation An exact method for quantifying the reliability of end-of-epidemic declarations in real time. The effects of local spatial structure on epidemiological invasions Pair approximations for spatial structures? Management of invading pathogens should be informed by epidemiology rather than administrative boundaries UK Government Office for National Statistics Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study SARS-CoV-2 infection among travelers returning from Wuhan 2020 The probability of detection of SARS-CoV-2 in saliva Mathematics of epidemics on networks: from exact to approximate models Epidemic processes in complex networks A novel field-based approach to validate the use of network models for disease spread between dairy herds Analysis of a stochastic SIR epidemic on a random network incorporating household structure Reproduction numbers for epidemic models with households and other social structures II: comparisons and implications for vaccination Reproductive numbers, epidemic spread and control in a community of households Reproduction numbers for epidemic models with households and other social structures.
    keywords: countries; cov-2; covid-19; data; disease; epidemic; exit; health; immunity; individuals; interventions; modelling; models; pandemic; population; r(t; sars; social; strategies; time; transmission
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        item: #3964 of 7819
          id: cord-303656-wtqwghon
      author: Faust, Jeremy
       title: Relative disease burdens of COVID-19 and seasonal influenza in New York City, February 1 - April 18, 2020.
        date: 2020-04-27
       words: 1440
      flesch: 52
     summary: We therefore calculated the ratio of excess deaths (i.e. assumed COVID-19 deaths) to seasonal influenza deaths during the same time interval and found a similar ratio of 21.1 COVID-19 to seasonal influenza deaths. However, these are calculated estimates based upon numerous assumptions, all of which reinforce the belief that influenza deaths are undercounted at multiple points in the healthcare system, from under testing, to underreporting of hospitalization, to under attribution on death certificates.
    keywords: covid-19; deaths; influenza
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        item: #3965 of 7819
          id: cord-303659-mzez7v4d
      author: Elsayed, Sarah M
       title: The Possibility and Cause of Relapse After Previously Recovering From COVID-19: A Systematic Review
        date: 2020-09-05
       words: 3205
      flesch: 51
     summary: As the most common comorbidity of COVID-19 patients, diabetes, and hypertension may affect the prognosis of the disease [8] . The publications included COVID-19 positive patient data and the relapse of disease was confirmed by PCR; the full text was available for these publications.
    keywords: covid-19; days; disease; patients; relapse; sars; study
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        item: #3966 of 7819
          id: cord-303660-2bxpqhro
      author: Direkoglu, C.
       title: Worldwide and Regional Forecasting of Coronavirus (Covid-19) Spread using a Deep Learning Model
        date: 2020-05-26
       words: 3989
      flesch: 59
     summary: The data includes the total number of daily new cases of Covid-19 worldwide, the cumulative total number of Covid-19 cases worldwide and the total number of deaths worldwide. Forecasting cumulative total number of Covid-19 cases worldwide using a model with RMSE of 39699 predicts that outbreak size may reach to 2,600,000 within the next 10 days and continue to grow linearly.
    keywords: cases; covid-19; data; deep; learning; model; number
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        item: #3967 of 7819
          id: cord-303661-etb19d6y
      author: Shin, Hyoung-Shik
       title: Empirical Treatment and Prevention of COVID-19
        date: 2020-06-22
       words: 4022
      flesch: 38
     summary: Tenofovir disoproxil fumarate/ emtricitabine (TDF/FTC), which has been prescribed for HIV-infected or hepatitis B virusinfected patients for a long time can be used safely as a short-term medicine for COVID-19 patients. Risk-adapted treatment strategy For COVID-19 patients Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern: the fragile balance between infections and autoimmunity A review of unfractionated heparin and its monitoring Nebulized heparin is associated with fewer days of mechanical ventilation in critically ill patients: a randomized controlled trial Inhibition of feline (FIPV) and human (SARS) coronavirus by semisynthetic derivatives of glycopeptide antibiotics Teicoplanin: an alternative drug for the treatment of COVID-19?
    keywords: coronavirus; cov-2; covid-19; hypersensitivity; immunity; patients; pneumonia; sars; symptoms; treatment; virus
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        item: #3968 of 7819
          id: cord-303667-z3tmy8hw
      author: Yousefzai, Rayan
       title: Misdiagnosis in the COVID era: When Zebras are Everywhere, Don’t Forget the Horses
        date: 2020-04-27
       words: 1097
      flesch: 53
     summary: COVID-19 patients can present with cardiovascular manifestations. We have to be vigilant in diagnosing COVID-19 patients; however, we should not forget about the common diagnosis.
    keywords: covid-19; patients
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        item: #3969 of 7819
          id: cord-303690-8h58rmwk
      author: Michelozzi, Paola
       title: Mortality impacts of the coronavirus disease (COVID-19) outbreak by sex and age: rapid mortality surveillance system, Italy, 1 February to 18 April 2020
        date: 2020-05-14
       words: 1947
      flesch: 49
     summary: key: cord-303690-8h58rmwk authors: Michelozzi, Paola; de’Donato, Francesca; Scortichini, Matteo; De Sario, Manuela; Noccioli, Fiammetta; Rossi, Pasqualino; Davoli, Marina title: Mortality impacts of the coronavirus disease (COVID-19) outbreak by sex and age: rapid mortality surveillance system, Italy, 1 February to 18 April 2020 date: 2020-05-14 journal: Euro Surveill DOI: 10.2807/1560-7917.es.2020.25.19.2000620 sha: doc_id: 303690 cord_uid: 8h58rmwk Data from the rapid mortality surveillance system in 19 major Italian cities were used to carry out a timely assessment of the health impact of the COVID-19 epidemic. Briefly, SiSMG is based on an ad hoc daily flow of mortality data (resident population by age and sex) from local Municipal Registry Offices to the Department of Epidemiology, Lazio Regional Health Authority -ASL
    keywords: cities; covid-19; excess; italy; mortality
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        item: #3970 of 7819
          id: cord-303703-ekhwb5xb
      author: Mash, Bob
       title: Primary care management of the coronavirus (COVID-19)
        date: 2020-03-31
       words: 3047
      flesch: 60
     summary: : A descriptive study Clinical features of patients infected with 2019 novel coronavirus in Wuhan Novel Coronavirus Pneumonia Emergency Response Epidemiology Team 2019-nCoV quick reference for health workers Guidelines for case-finding, diagnosis, management and public health response in South Africa Clinical management of suspected or confirmed COVID-19 disease Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected I declare that I have no financial or personal relationships that may have inappropriately influenced me in writing this article. Mild cases can be managed at home with self-isolation, symptomatic treatment and follow-up if the disease worsens.
    keywords: care; case; covid-19; infection; patients; people; swab
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        item: #3971 of 7819
          id: cord-303718-7bpap31f
      author: Binder, Adam F.
       title: Treating Hematologic Malignancies During a Pandemic: Utilizing Telehealth and Digital Technology to Optimize Care
        date: 2020-06-26
       words: 3124
      flesch: 30
     summary: Tools for enabling decentralized care include (10) telehealth visits, home based care, and remote patient monitoring. The swift adoption of decentralization strategies like telehealth visits, home-based care, and remote patient monitoring can allow physicians treating hematologic malignancies to maintain care while mitigating the risk of nosocomial SARS-COV-2 infection.
    keywords: cancer; care; covid-19; home; monitoring; patients; telehealth; treatment; visits
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        item: #3972 of 7819
          id: cord-303731-yrlzxtbw
      author: Fong, Raymond
       title: Management of Dysphagia in Nursing Homes During the COVID-19 Pandemic: Strategies and Experiences
        date: 2020-08-18
       words: 2902
      flesch: 40
     summary: key: cord-303731-yrlzxtbw authors: Fong, Raymond; Tsai, Kelvin C. F.; Tong, Michael C. F.; Lee, Kathy Y. S. title: Management of Dysphagia in Nursing Homes During the COVID-19 Pandemic: Strategies and Experiences date: 2020-08-18 journal: SN Compr Clin Med DOI: 10.1007/s42399-020-00464-0 sha: doc_id: 303731 cord_uid: yrlzxtbw The global 2019 novel coronavirus disease (COVID-19) pandemic has had devastating effects not only on healthcare systems worldwide but also on different aspects of the care provided to nursing home residents. Dysphagia is a prevalent problem among nursing home residents.
    keywords: covid-19; dysphagia; management; nursing; pandemic; residents; risk
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        item: #3973 of 7819
          id: cord-303741-1ou0cy5k
      author: Stafstrom, Carl E.
       title: COVID-19: Neurological Considerations in Neonates and Children
        date: 2020-09-10
       words: 7042
      flesch: 34
     summary: The purpose of this review is twofold: (1) to discuss the available data about COVID-19 infections in neonates and children, and (2) to provide a perspective about potential neurologic involvement in neonates and children with COVID-19 infections, in view of neurobiological development. In the context of COVID-19 infection, the BBB may be dysfunctional, disrupted either by inflammatory response or the virus itself, allowing transmission of the virus or activated immune cells from the circulation into the CNS
    keywords: brain; children; cns; coronavirus; cov-2; covid-19; disease; infection; involvement; sars; symptoms; syndrome; virus
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        item: #3974 of 7819
          id: cord-303747-o09canse
      author: Bennett, Courtney E.
       title: ST-segment Elevation, Myocardial Injury, and Suspected or Confirmed COVID-19 Patients: Diagnostic and Treatment Uncertainties
        date: 2020-04-11
       words: 2584
      flesch: 22
     summary: These experiences emphasize the need for health care facilities to rapidly prepare and configure their own STEMI systems of care in anticipation of treating increasing numbers of COVID-19 patients whose clinical course is complicated by the appearance of STE on their electrocardiogram. This algorithm seeks to achieve the following objectives: 1) the accurate identification of patients with type 1 or type 2 MI who would benefit from reperfusion therapy and revascularization; 2) the minimization/avoidance of unnecessary exposure of COVID-19 patients to invasive care and pharmacological management that may result in clinical harm; and 3) a strategy to wisely utilize resources and avoid unnecessary exposure to a potentially fatal infectious agent.
    keywords: cardiac; covid-19; elevation; injury; patients; segment; ste
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        item: #3975 of 7819
          id: cord-303785-2y4a1luj
      author: Suárez, V.
       title: Epidemiología de COVID-19 en México: del 27 febrero al 30 de abril de 2020
        date: 2020-05-27
       words: 4725
      flesch: 54
     summary: La comparación de las características de la epidemia en los primeros 64 días tras el diagnóstico del caso índice entre México y China, muestran los siguientes hallazgos: el número de diagnósticos confirmados en México fue un 76% menor que en China, que contaba con 80.304 casos, y el número de defunciones representó un 37% menor del reportado por China. La media de edad de los pacientes fue de 46 años, en un rango de 0 a 104 años.
    keywords: 2020; abril; años; casos; china; como; con; confirmados; coronavirus; covid-19; del; entre; estado; este; hasta; las; los; marzo; más; méxico; número; pacientes; para; personas; por; que; una
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        item: #3976 of 7819
          id: cord-303787-dx1n8jap
      author: Vonck, Kristl
       title: Neurological manifestations and neuro‐invasive mechanisms of the severe acute respiratory syndrome coronavirus type 2
        date: 2020-05-16
       words: 3812
      flesch: 33
     summary: Viruses Middle East respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4 Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways Detection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndrome A first Case of Meningitis/Encephalitis associated with SARS-Coronavirus-2 Angiotensin-converting enzyme 2 in the brain: Properties and future directions The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients Accepted Article The increase in D-Dimer levels appears to be higher in COVID-19 patients with CVD compared to patients without CVD (median levels of 900 microg/l) but this is a finding that will need to be further investigated and documented 3, 9 .
    keywords: acute; article; copyright; cov-2; covid-19; manifestations; patients; sars; symptoms
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        item: #3977 of 7819
          id: cord-303791-yw80ndg6
      author: Ashique, Karalikkattil T.
       title: Teledermatology in the Wake of COVID -19 Scenario: An Indian Perspective
        date: 2020-05-10
       words: 3660
      flesch: 45
     summary: This helps increase correctness as the instructions can be verbally conveyed at ease to the pharmacy and even alternative medications can be suggested at ease � WhatsApp business account is one app that can be exploited for teledermatology consultations. The business account also has the advantage of setting automated replies to messages which can be used to convey information, instructions, and disclaimers about teledermatology consultations to anyone who connects.
    keywords: consultations; covid-19; doctor; india; patient; teledermatology; telemedicine; time
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        item: #3978 of 7819
          id: cord-303799-9hh17k86
      author: Huang, Ying
       title: Clinical characteristics of 36 non-survivors with COVID-19 in Wuhan, China
        date: 2020-02-29
       words: 2802
      flesch: 56
     summary: In our cohort, lymphocytopenia occurred in more than 70% of patients at admission, which is a main laboratory feature in COVID-19 patients 15, 17 . Patients had common clinical symptoms of fever (34 [94.44%] patients), cough (28 [77.78%] patients), shortness of breath (21 [58.33%] patients), and fatigue (17 [47.22%] patient).
    keywords: covid-19; medrxiv; patients; preprint; study
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        item: #3979 of 7819
          id: cord-303811-vr5nao8w
      author: Binson, Guillaume
       title: Preparation and physicochemical stability of 50 mg/ml hydroxychloroquine oral suspension in Syrspend pH4 dry
        date: 2020-10-16
       words: 3062
      flesch: 35
     summary: In order to investigate the physical and chemical stability of hydroxychloroquine oral suspension, three bottles from different batches of hydroxychloroquine suspensions were stored throughout the study duration under controlled refrigeration (5 ± 3 °C) (temperature was monitored daily). Indeed, during the period of testing, the proportion of the initial hydroxychloroquine concentration remaining was within the limit set by the U.S. Pharmacopeia [13] , meaning that hydroxychloroquine oral suspension was stable up to at least 60 days under refrigeration (5 ± 3°C).
    keywords: covid-19; hydroxychloroquine; liquid; patients; suspension; water
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        item: #3980 of 7819
          id: cord-303819-w1785lap
      author: Cortegiani, Andrea
       title: Update I. A systematic review on the efficacy and safety of chloroquine/hydroxychloroquine for COVID-19
        date: 2020-07-11
       words: 3477
      flesch: 47
     summary: Evidence from available data suggests that monitoring baseline and subsequent (e.g. daily) ECG during treatment especially in high risk patients with known risk. Although this trial seems appropriately powered and has a low risk of bias, delayed initiation of treatment (usually ≥3 days) and the use of self-reported outcomes make it Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review Hydroxychloroquine in the management of patients with COVID-19: the need for an evidence base A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 Chloroquine for COVID-19: rationale, facts, hopes Including non-randomized studies on intervention effects RoB 2: A revised tool for assessing risk of bias in randomised trials ROBINS-I: A tool for assessing risk of bias in non-randomised studies of interventions Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses Risk-of-bias VISualization (robvis): An R package and Shiny web app for visualizing risk-of-bias assessments Synthesizing and presenting findings using other methods | Cochrane Training A pilot study of hydroxychloroquine in coronavirus disease-19 (COVID-19) Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19 Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial Low dose of hydroxychloroquine reduces fatality of critically ill patients with COVID-19 Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Early J o u r n a l P r e -p r o o f treatment of COVID-19 patients with hydroxychloroquine and azithromycin:
    keywords: covid-19; hcq; hydroxychloroquine; patients; risk; studies; treatment
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        item: #3981 of 7819
          id: cord-303860-jpy373ph
      author: Huang, Zhifeng
       title: Occupational Exposure to SARS-CoV-2 in Burns Treatment During the COVID-19 Epidemic: Specific Diagnosis and Treatment Protocol
        date: 2020-04-23
       words: 3086
      flesch: 41
     summary: Following an in-depth study of the latest literature on COVID-19 diagnosis and treatment, we reviewed the protocols surrounding hospitalization of patients with extensive burns in our hospital and, in accordance with the epidemiological characteristics of COVID-19, developed an algorithm for protection during diagnosis and treatment of burn patients. Because of systemic inflammatory response syndrome and large amount of rehydration treatment, burn patients are prone to pulmonary edema.
    keywords: coronavirus; covid-19; healthcare; infection; patients; protection; treatment
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        item: #3982 of 7819
          id: cord-303880-zv4nbz9p
      author: Tsikala Vafea, Maria
       title: Emerging Technologies for Use in the Study, Diagnosis, and Treatment of Patients with COVID-19
        date: 2020-06-24
       words: 5492
      flesch: 39
     summary: 19 Re-cently, deep learning models, the core algorithms of AI, have been used to develop a thoracic CT image analysis system, which can automatically detect COVID-19 patients and quantify the disease burden. Frontline healthcare practitioners, including CT and MRI technicians, are at high risk for contracting the virus given their frequent exposure to COVID-19 patients.
    keywords: coronavirus; covid-19; data; development; disease; health; learning; models; pandemic; patients; sars; use; vaccine; virus
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        item: #3983 of 7819
          id: cord-303917-2tu707ng
      author: Zhang, Lei
       title: Potential interventions for novel coronavirus in China: A systematic review
        date: 2020-03-03
       words: 5438
      flesch: 36
     summary: The effect of ascorbic acid on infection chick-embryo ciliated tracheal organ cultures by coronavirus Nutrients and their role in host resistance to infection Vitamin C intake and susceptibility to pneumonia Vitamin D insufficiency among free-living healthy young adults Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease Acute phase response elicited by experimental bovine diarrhea virus (BVDV) infection is associated with decreased vitamin D and E status of vitamin-replete preruminant calves Vitamin E metabolic effects and genetic variants: a challenge for precision nutrition in obesity and associated disturbances Vitamin E deficiency intensifies the myocardial injury of coxsackievirus B3 infection of mice Increased virulence of coxsackievirus B3 in mice due to vitamin E or selenium deficiency Macrophage-derived extracellular vesicles induce long-lasting immunity against hepatitis C virus which is blunted by polyunsaturated fatty acids Plasma fatty acid levels in patients with acquired immune deficiency syndrome and in controls The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza Anti-HCV activities of selective polyunsaturated fatty acids Selenium and human health Micronutrients and host resistance to viral infection Review: micronutrient selenium deficiency influences evolution of some viral infectious diseases Selenium deficiency increases the pathology of an influenza virus infection Rapid genomic evolution of a non-virulent coxsackievirus B3 in selenium-deficient mice results in selection of identical virulent isolates Combined adjuvant effect of ginseng stem-leaf saponins and selenium on immune responses to a live bivalent vaccine of Newcastle disease virus and infectious bronchitis virus in chickens Zinc and immunity: an essential interrelation Zinc deficiency Zinc supplementation for the treatment of measles in children Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture Crossing the iron gate: why and how transferrin receptors mediate viral entry Childhood iron deficiency anemia leads to recurrent respiratory tract infections and gastroenteritis Chicken interferon type I inhibits infectious bronchitis virus replication and associated respiratory illness Prevention of experimental coronavirus colds with intranasal alpha-2b interferon Ribavirin and interferon-beta synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds Interferon priming enables cells to partially overturn the SARS coronavirus-induced block in innate immune activation Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial Pegylated interferon-alpha protects type 1 pneumocytes against SARS coronavirus infection in macaques Proposal for vaccination against SARS coronavirus using avian infectious bronchitis virus strain H from The Netherlands Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study Current treatment options and the role of peptides as potential therapeutic components for Middle East Respiratory Syndrome (MERS): a review Uses of intravenous gammaglobulin in immune hematologic disease Acute respiratory distress syndrome in critically ill patients with severe acute respiratory syndrome Strokes, thromboembolic events, and IVIg: rare incidents blemish an excellent safety record Thymosin alpha 1 and HIV-1: recent advances and future perspectives A reappraisal of thymosin alpha1 in cancer therapy Serum thymosin alpha 1 levels in normal and pathological conditions Thymosin alpha 1 antagonizes dexamethasone and CD3-induced apoptosis of CD4+ CD8+ thymocytes through the activation of cAMP and protein kinase C dependent second messenger pathways Clinical investigation of outbreak of nosocomial severe acute respiratory syndrome Anti-SARS coronavirus agents: a patent review (2008-present) Modulation of immune response in aged humans through different administration modes of thymopentin Phase variation in the modulation of the human immune response Thymopentin as adjuvant in non-responders or hyporesponders to hepatitis B vaccination The general immunopharmacology of levamisole Lymphocyte subsets in measles. Depressed helper/inducer subpopulation reversed by in vitro treatment with levamisole and ascorbic acid Systemic cyclosporine and corneal transplantation Nucleocapsid protein of SARS coronavirus tightly binds to human cyclophilin A Factor in virus replication and potential target for anti-viral therapy The SARS-coronavirus-host interactome: identification of cyclophilins as target for pancoronavirus inhibitors Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus Diarylheptanoids from Alnus japonica inhibit papain-like protease of severe acute respiratory syndrome coronavirus Cinanserin is an inhibitor of the 3C-like proteinase of severe acute respiratory syndrome coronavirus and strongly reduces virus replication in vitro Flavonoids: an overview Flavonoids from pterogyne nitens inhibit hepatitis C virus entry Inhibition of SARS-CoV 3CL protease by flavonoids Characteristics of flavonoids as potent MERS-CoV 3C-like protease inhibitors Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition Angiotensin-converting enzyme-2: a molecular and cellular perspective Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus The secret life of ACE2 as a receptor for the SARS virus Characterization of severe acute respiratory syndromeassociated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry Severe acute respiratory syndrome coronavirus entry into host cells: Opportunities for therapeutic intervention Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association Effects of chloroquine on viral infections: an old drug against today's diseases? Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Membrane-related effects underlying the biological activity of the anthraquinones emodin and barbaloin Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 interaction Old drugs as lead compounds for a new disease?
    keywords: acute; addition; coronavirus; cov; covid-19; human; immune; infection; patients; replication; sars; syndrome; treatment; vitamin
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        item: #3984 of 7819
          id: cord-303959-e1654g5j
      author: Vitiello, Antonio
       title: COVID-19 Patients with Pulmonary Fibrotic Tissue: Clinical Pharmacological Rational of Antifibrotic Therapy
        date: 2020-08-27
       words: 1919
      flesch: 29
     summary: In this article, we describe the advantages of antifibrotic therapy in patients with ongoing SARS-CoV-2 viral infection to prevent the worsening and aggravation of the clinical situation, and the advantages it could have in the role of preventing pulmonary fibrosis after SARS-CoV-2 infection, and in accelerating the complete healing process. SARS-CoV-2 infection can have a completely asymptomatic or mildly symptomatic course, but in some cases, it can also cause systemic hyperinflammation, pulmonary fibrosis and scarring with lung collapse, multi-organ dysfunction, and patient death
    keywords: covid-19; fibrosis; infection; sars
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        item: #3985 of 7819
          id: cord-303960-86mukxg1
      author: Rahimi, Farid
       title: Tackling the COVID-19 Pandemic
        date: 2020-04-24
       words: 1759
      flesch: 43
     summary: Predictably, the present pandemic will wane, but future waves of COVID-19 outbreaks may emerge (10) (11) (12) , potentially seasonally. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak Pathological findings of COVID-19 associated with acute respiratory distress syndrome Structural basis for the recognition of the SARS-CoV-2 by fulllength human ACE2 Transmission routes of respiratory viruses among humans Network theory and SARS: predicting outbreak diversity MERS outbreak in Korea: hospital-to-hospital transmission
    keywords: coronavirus; covid-19; outbreak; pandemic; sars
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        item: #3986 of 7819
          id: cord-303991-pjycxlse
      author: Shah, M. R. T.
       title: Finding the real COVID-19 case-fatality rates for SAARC countries
        date: 2020-10-27
       words: 2989
      flesch: 51
     summary: Therefore, survival interval and underreported cases should be considered while calculating COVID-19 CFR. However, no study has thoroughly investigated COVID-19 adjusted CFR of the South Asian Association for Regional Cooperation (SAARC) countries.
    keywords: bangladesh; cases; cfr; countries; covid-19; crude
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        item: #3987 of 7819
          id: cord-304010-n4gxxl5i
      author: Sung, Ho Kyung
       title: Clinical Course and Outcomes of 3,060 Patients with Coronavirus Disease 2019 in Korea, January–May 2020
        date: 2020-07-28
       words: 3423
      flesch: 52
     summary: World Health Organization Estimates of the severity of coronavirus disease 2019: a model-based analysis Korean Society of Infectious Diseases; Korean Society of Pediatric Infectious Diseases Report on the epidemiological features of coronavirus disease 2019 (COVID-19) outbreak in the Clinical Outcomes of COVID-19 Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Remdesivir for the treatment of Covid-19 -Preliminary report Operating protocols of a community treatment center for isolation of patients with coronavirus disease Clinical course of asymptomatic and mildly symptomatic patients with coronavirus disease admitted to community treatment centers Observational study of hydroxychloroquine in hospitalized patients with Covid-19 A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 Towards a better response to the next wave of the pandemic, the clinical course and outcomes of COVID-19 patients need to be defined.
    keywords: age; covid-19; need; oxygen; patients; therapy
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        item: #3988 of 7819
          id: cord-304013-nzigx0k0
      author: Lipinski, Tom
       title: Review of ventilation strategies to reduce the risk of disease transmission in high occupancy buildings
        date: 2020-09-13
       words: 12837
      flesch: 43
     summary: Bidirectional ventilation system Natural ventilation relies on natural driving forces. The British standards BS EN 16798-3:2017 defines 4 basic types of ventilation systems:
    keywords: air; buildings; cov-2; covid-19; disease; droplets; figure; flow; heat; indoor; infection; number; particles; rate; risk; room; sars; spread; transmission; ventilation; ventilation systems; virus
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        item: #3989 of 7819
          id: cord-304016-4o2bpedp
      author: Hanage, William P.
       title: COVID-19: US federal accountability for entry, spread, and inequities—lessons for the future
        date: 2020-11-02
       words: 5710
      flesch: 44
     summary: With only 4% of the worldwide population, the US has seen about 22% of COVID-19 deaths. With only 4% of the worldwide population, the US has seen about 22% of COVID-19 deaths.
    keywords: age; cases; complaints; covid-19; data; deaths; excess; federal; health; mortality; osha; pandemic; population
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        item: #3990 of 7819
          id: cord-304018-1fxjdl1m
      author: Peters, Sanne A.E.
       title: Obesity as a risk factor for COVID‐19 mortality in women and men in the UK Biobank: comparisons with influenza/pneumonia and coronary heart disease
        date: 2020-09-23
       words: 1994
      flesch: 51
     summary: A one standard deviation higher BMI was associated with a stronger risk of COVID-19 and influenza/pneumonia mortality in women than men: HRs for COVID-19 mortality (95%CIs) were 1.51 (1.34; 1.71) in women and 1.26 (1.11; 1.44) in men, leading to a women:men RHR of 1.20 (95%CI: 1.00 1.43). Women's Health Excess weight and COVID-19: insights from new evidence OpenSAFELY: factors associated with COVID-19 death in 17 million patients The sex-specific association between BMI and coronary heart disease: a systematic review and meta-analysis of 95 cohorts with 1·2 million participants UK biobank: an open access resource for identifying the causes of a wide range of complex diseases of middle and old age Floating absolute risk: an alternative to relative risk in survival and case-control analysis avoiding an arbitrary reference group Rationale and tutorial for analysing and reporting sex differences in cardiovascular associations Body mass index and the risk of COVID-19 across ethnic groups: Analysis of UK Biobank This article is protected by copyright.
    keywords: covid-19; mortality; risk; women
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        item: #3991 of 7819
          id: cord-304035-s9tkyuso
      author: Inal, Jameel
       title: Biological Factors Linking ApoE ε4 Variant and Severe COVID-19
        date: 2020-10-02
       words: 963
      flesch: 33
     summary: Compared with the more common ApoE ε3ε3 genotype, the risk of severe COVID-19 for people carrying two ApoE ε4 alleles was doubled (OR = 2.31), including people who had neither developed Alzheimer's disease (AD) (as for the 5.13% COVID-19positive participants) nor cardiovascular disease (CVD), and for whom two copies of ApoE ε4 also carried increased risk. Analysis of data from 382,188 participants of the European ancestry in the UK Biobank [2] revealed a high risk of severe COVID-19, in the 2.36% (n = 9022) of people carrying two copies of the faulty gene variant of ApoE ε4, with 5.13% (n = 37) of the COVID-19-positive participants after hospitalization carrying this gene variant.
    keywords: apoe; covid-19; risk
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        item: #3992 of 7819
          id: cord-304063-yb8rfd8r
      author: Din, Misbahud
       title: COVID‐19 and dengue coepidemics: A double trouble for overburdened health systems in developing countries
        date: 2020-07-28
       words: 605
      flesch: 48
     summary: Measures should be taken to distinguish cases with fever and headache from COVID-19 and dengue fever and these atypical symptoms must trigger alerts in developing countries with high dengue fever incidence. Such predications are based Cocirculations of two genotypes of dengue virus in 2006 out-break of dengue hemorrhagic fever in Karachi Viremia and clinical presentation in Nicaraguan patients infected with Zika virus, chikungunya virus, and dengue virus The global distribution and burden of dengue Refining the global spatial limits of dengue virus transmission by evidence-based consensus Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Covert COVID-19 and falsepositive dengue serology in Singapore Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period Reviewing the history of pandemic influenza: understanding patterns of emergence and transmission COVID-19 in Latin America: the implications of the first confirmed case in Brazil
    keywords: covid-19; dengue
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        item: #3993 of 7819
          id: cord-304088-xkg0ylz8
      author: Zhu, Han
       title: Cardiovascular Complications in Patients with COVID-19: Consequences of Viral Toxicities and Host Immune Response
        date: 2020-04-21
       words: 5545
      flesch: 33
     summary: The mechanism of cardiac injury is unclear but likely involves a combination of direct viral damage and immune-mediated damage by inflammatory cytokines/chemokines and cytotoxic immune cell response in the later stages of infection. In order to better understand the biology of viral immune response and how it impacts the heart, we explore here the basic biological mechanisms underlying viral entry into the host cells and the subsequent immune response.
    keywords: acute; cells; coronavirus; cov-2; covid-19; disease; infection; injury; patients; protein; response; sars
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        item: #3994 of 7819
          id: cord-304101-b9na3yf6
      author: Yong, Suh Kuan
       title: Molecular Targets for the Testing of COVID‐19
        date: 2020-05-18
       words: 1780
      flesch: 38
     summary: Although the protein testing method is similar, the targets are not part of the virus and the testing specimens used can be quite different as compared to those for viral protein detection. It also shows the complexity and time consumed in obtaining and screening an antibody for an unbiased test targeting specific viral protein.
    keywords: cov-2; covid-19; detection; protein; sars; testing
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        item: #3995 of 7819
          id: cord-304108-kn9v8qmz
      author: Aksu, Kurtuluş
       title: Factors determining COVID‐19 pneumonia severity in a country with routine BCG vaccination
        date: 2020-08-19
       words: 2651
      flesch: 40
     summary: This is the first study to evaluate severity of clinical condition with BCG-vaccination status in Population characteristics of countries such as population density, median age, and urban population and mainly SARS-CoV-2 test rates are major confounders that may lead to misjudgement of BCG vaccination policy is beneficial. All rights reserved Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination Mandated Bacillus CalmetteGuérin (BCG) vaccination predicts flattened curves for the spread of Epidemiological Determinants of Acute Respiratory Syndrome Coronavirus-2 Disease Pandemic and The Role of the Bacille Vaccine in Reducing Morbidity and Mortality The influence of BCG immunisation on tuberculin reactivity and booster effect in adults in a country with a high prevalence of tuberculosis Exercising caution in correlating COVID-19 incidence and mortality rates with BCG vaccination policies due to variable rates of SARS CoV-2 testing SARS-CoV-2 Rates in BCG-Vaccinated and Unvaccinated Young Adults Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China Chinese Center for Disease Control and Prevention Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 2019 -United States Accepted Article coronavirus disease 2019:
    keywords: bcg; covid-19; disease; patients; pneumonia; study; vaccination
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        item: #3996 of 7819
          id: cord-304115-xs54f295
      author: Zamaniyan, Marzieh
       title: Preterm delivery in pregnant woman with critical COVID‐19 pneumonia and vertical transmission
        date: 2020-04-17
       words: 1798
      flesch: 46
     summary: Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. All rights reserved World Health Organization Real estimates of mortality following COVID-19 infection.
    keywords: covid-19; delivery; disease; neonate; sars; transmission
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        item: #3997 of 7819
          id: cord-304124-ym9mf5wz
      author: Li, Jia
       title: Meta-analysis investigating the relationship between clinical features, outcomes, and severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia
        date: 2020-06-12
       words: 2739
      flesch: 43
     summary: Compared with non-severe patients, those with severe illness or admission to the ICU were more likely to have one or more comorbidities (OR=3.07, 95% CI: 1.56-6.05, P<0.001, I 2 =79.0%), including chronic obstructive pulmonary disease (OR=5.08, 95% CI: 2.68-9.63, P<0.001, Figure 1A -1G) . Severely ill patients or those cared for in the ICU had a higher mortality rate and lower discharge rate than non-severe patients or patients without ICU admission.
    keywords: clinical; covid-19; disease; icu; patients; studies
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        item: #3998 of 7819
          id: cord-304157-u0mlee6u
      author: Nyasulu, Juliet
       title: The effects of coronavirus disease 2019 pandemic on the South African health system: A call to maintain essential health services
        date: 2020-07-22
       words: 4421
      flesch: 42
     summary: Assessing the effects of COVID-19 on South African health system is critical to identify challenges and act timely to strike a balance between managing the emergency and maintaining essential health services. Assessing the effects of COVID-19 on South African health system is critical to identify challenges and act timely to strike a balance between managing the emergency and maintaining essential health services.
    keywords: africa; covid-19; emergency; epi; health; hiv; pandemic; services; south; system
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        item: #3999 of 7819
          id: cord-304203-lhqvi3j0
      author: Barman, Manash Pratim
       title: COVID-19 pandemic and its recovery time of patients in India: A pilot study
        date: 2020-07-09
       words: 1686
      flesch: 59
     summary: This information on recovery time of Covid-19 patients will help planners to chalk out effective strategies. But this difference in recovery time of Covid-19 patients of age less than 60 years and more than 60 years is not significantly different.
    keywords: covid-19; patients; recovery; time
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        item: #4000 of 7819
          id: cord-304208-jwlc8fxj
      author: Vagni, Monia
       title: Coping With COVID-19: Emergency Stress, Secondary Trauma and Self-Efficacy in Healthcare and Emergency Workers in Italy
        date: 2020-09-03
       words: 8636
      flesch: 39
     summary: We study differences between healthcare (n = 121) and emergency workers (n = 89) in terms of their coping strategies, emergency stress, and secondary trauma, as well as the relationships of these differences to demographic variables and other stress factors (Instructions and Equipment). The analyses reveal that compared with the emergency worker group, the health worker group has greater levels of emergency stress and arousal and is more willing to use problem-focused coping.
    keywords: coping; covid-19; emergency; emergency workers; et al; factors; group; healthcare; levels; strategies; stress; study; trauma; workers
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        item: #4001 of 7819
          id: cord-304219-tmlatghe
      author: Ojha, Rashi
       title: Challenges faced by mental health providers and patients during the coronavirus 2019 pandemic due to technological barriers
        date: 2020-06-03
       words: 1504
      flesch: 29
     summary: Medicare Telemedicine Health Care Provider Fact Sheet The outbreak of COVID-19 coronavirus and its impact on global mental health 2019-nCoV epidemic: address mental health care to empower society Inevitable isolation and the change of stress markers The psychological effect of severe acute respiratory syndrome on emergency department staff Rethinking online mental health services in China during the COVID-19 epidemic Remote consultations in the era of COVID-19 pandemic: Preliminary experience in a regional Australian public acute mental health care setting Patients with mental health disorders in the COVID-19 epidemic Older adults perceptions of technology and barriers to interacting with tablet computers: a focus group study Digital Divide Persists Even as Lower-Income Americans Make Gains in Tech Adoption 70% Of Seniors Are Now Online and Using Technology CMS Expands COVID-19 Telehealth Reimbursement to Therapists Technology Use and Attitudes among Mid-Life and Older Americans Progression of mental health services during the COVID-19 outbreak in China Mental health problems of prison and jail inmates Notification of Enforcement Discretion for Telehealth This healthcare disparity is accentuated in the area of mental health services, where the clinical systems lack technological sophistication to meet the challenges of the pandemic.
    keywords: covid-19; health; pandemic; services
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        item: #4002 of 7819
          id: cord-304230-rxhoe8cw
      author: Hay-David, A.G.C.
       title: Reducing medical error during a pandemic
        date: 2020-04-11
       words: 1991
      flesch: 49
     summary: The C2 element was of particular relevance when a single point of contact (SPOC) is established, which in turn reduces the bandwidth of other team members, regular situation reports (SITREPs) are briefed to ensure that every team member is informed and can add value during this update. key: cord-304230-rxhoe8cw authors: Hay-David, A.G.C.; Herron, J.B.T.; Gilling, P.; Miller, A.; Brennan, P.A. title: Reducing medical error during a pandemic date: 2020-04-11 journal:
    keywords: care; covid-19; media; medical; pandemic; team
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        item: #4003 of 7819
          id: cord-304280-2a84u4tm
      author: Masic, Izet
       title: Public Health Aspects of COVID-19 Infection with Focus on Cardiovascular Diseases
        date: 2020-03-17
       words: 4697
      flesch: 37
     summary: Then, a few days ago, French researchers showed in a very small group of patients that the concomitant administration of hydroxychloroquine and azithromycin (Sumamed) had an even better effect in COVID-19 patients. Published case reports from the Chinese Centers for Disease Control indicate patients with underlying comorbid conditions have a heighted risk for contracting COVID-19 and a worse prognosis; depending on the report, between 25% and 50% of COVID-19 patients present with underlying conditions.
    keywords: care; covid-19; disease; health; infection; pandemic; patients; risk; sars; treatment; virus
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        item: #4004 of 7819
          id: cord-304282-om2xc4bs
      author: Berhan, Yifru
       title: Will Africa be Devastated by Covid-19 as Many Predicted? Perspective and Prospective
        date: 2020-05-17
       words: 5349
      flesch: 53
     summary: Therefore, as the very recently confirmed case reports showed, the assumption is that the virus carriers are already within the community, and probably in many other African countries too. The case load curves of many African countries are also waxing and waning type; a steady type of increment is not yet observed in the last 2-3 months, which is against with an exponential spread.
    keywords: africa; case; countries; covid-19; deaths; europe; influenza; sars; zone
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        item: #4005 of 7819
          id: cord-304285-mfztp5om
      author: McNabb-Baltar, Julia
       title: Lipase Elevation in Patients With COVID-19
        date: 2020-06-03
       words: 1233
      flesch: 44
     summary: Hg compared with patients with normal serum lipase (44% vs 14%). Among hyperlipasemia patients, there were 4 (44.4%) that required ICU stay and 3 (33.3%) deaths.
    keywords: covid-19; hyperlipasemia; pancreatitis; patients
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        item: #4006 of 7819
          id: cord-304306-rxjahqwh
      author: Vlachakis, Dimitrios
       title: Molecular mechanisms of the novel coronavirus SARS-CoV-2 and potential anti-COVID19 pharmacological targets since the outbreak of the pandemic
        date: 2020-10-08
       words: 8538
      flesch: 33
     summary: A different function of the N protein is its interaction with the protease subunit p42, which degrades viral proteins . Specifically, this interaction may impair proteolysis of viral proteins and their presentation to Cytotoxic T-Lymphocytes, thus promoting viral evasion from immune effectors .
    keywords: activity; binding; cell; coronavirus; cov-2; covid-19; domain; drug; et al; helicase; inhibitors; membrane; polymerase; protease; protein; replication; rna; sars; spike; structure; target
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        item: #4007 of 7819
          id: cord-304313-nuz5yvht
      author: Esser, Charlotte
       title: COVID-19 research: toxicological input urgently needed!
        date: 2020-06-05
       words: 1186
      flesch: 39
     summary: Third, there is the issue of air pollution. It goes in two directions: on the one hand, evidence suggests that due to lock-down measures and less traffic, the amount of air pollution has significantly decreased in some regions, giving great opportunities for epidemiological-toxicological research.
    keywords: air; covid-19; disease; pollution
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        item: #4008 of 7819
          id: cord-304321-y177sqee
      author: Cho, Ryan H. W.
       title: Pearls of experience for safe and efficient hospital practices in otorhinolaryngology—head and neck surgery in Hong Kong during the 2019 novel coronavirus disease (COVID-19) pandemic
        date: 2020-05-15
       words: 4380
      flesch: 39
     summary: Moreover, COVID-19 patients as young as 3 days have been reported [23] . Recommendations on implementing isolation precautions in hospital settings Rational use of personal protective equipment for coronavirus disease (COVID-19): Interim guidance Considerations for recommending extended use and limited reuse of filtering facepiece respirators in health care settings Recovering the infective route of super-spreaders SARS-CoV-2 viral load in upper respiratory specimen of infected patients Suggestions for prevention of 2019 novel coronavirus infection in otolaryngology head and neck surgery medical staff Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Tracheostomy during SARS Tumor progression in waiting time for radiotherapy in head and neck cancer Recurrent thyroid cancer: role of surgery versus radioactive iodine Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts' consensus statement A case report of neonatal COVID-19 infection in China A case series of children with 2019 novel coronavirus infection: clinical and epidemiological features Successful telemedicine programs in otolaryngology Validation study of portable device for the diagnosis of obstructive sleep apnea according to the new AASM scoring criteria: Watch-PAT 100 Diagnosis of obstructive sleep apnea by peripheral arterial tonometry: meta-analysis Infection control in audiological practice Infection prevention and control guidelines for audiology Health care workers are at high risk of catching COVID-19.
    keywords: cases; china; coronavirus; covid-19; healthcare; hospital; infection; pandemic; patients; personnel; procedures; sars
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        item: #4009 of 7819
          id: cord-304327-mtkgr542
      author: Jouffroy, Romain
       title: Prehospital pulse oximetry: a red flag for early detection of silent hypoxemia in COVID-19 patients
        date: 2020-06-08
       words: 651
      flesch: 45
     summary: In summary, this retrospective study based on prehospital first responder data highlighted a relatively higher discrepancy between SpO2i and RRi in COVID-19 ARF patients, in comparison with previous non-COVID-19 ARF patients. After having measured the SpO2i/RRi values in COVID-19 patients, we compared them to those of non-COVID-19 patients (i.e., patients with other causes of ARF treated by the BLS teams over the previous 3 years in the same period).
    keywords: covid-19; patients
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        item: #4010 of 7819
          id: cord-304328-6lwhuido
      author: Khaled, Arwa
       title: The Knowledge and Attitude of the Community from the Aseer Region, Saudi Arabia, Toward COVID-19 and Their Precautionary Measures Against the Disease
        date: 2020-09-30
       words: 3839
      flesch: 46
     summary: University-educated participants scored significantly higher for all knowledge items than those from other educational levels (see Table 2 ); however, knowledge scores did not differ significantly across age groups, except for item K10. Furthermore, the main source of COVID-19 information was the Ministry of Health website 661 (89.3%).
    keywords: attitude; covid-19; knowledge; measures; participants; saudi; score; study
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        item: #4011 of 7819
          id: cord-304340-9mrtic2k
      author: Karacan, Ilker
       title: The origin of SARS-CoV-2 in Istanbul: Sequencing findings from the epicenter of the pandemic in Turkey
        date: 2020-05-15
       words: 2996
      flesch: 51
     summary: Turkey is one of the latest countries that COVID-19 disease was reported, with the first case on March 11, 2020, and since then, Istanbul became the epicenter of the pandemic in Turkey. Patients with various clinical presentations (one asymptomatic, one moderate, and one with severe pulmonary infiltration) were included in this study.
    keywords: coronavirus; cov-2; covid-19; disease; isolates; istanbul; patient; sars; sequencing
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        item: #4012 of 7819
          id: cord-304352-zdxztb5h
      author: Montgomery, Robert A.
       title: COVID-19, Health, Conservation, and Shared Wellbeing: Details Matter
        date: 2020-06-04
       words: 905
      flesch: 45
     summary: A new coronavirus associated with human respiratory disease in China World Health Organization, Coronavirus disease (COVID-19) Pandemic Impact of Non-Pharmaceutical Interventions (NPIs) to Reduce COVID-19 Mortality and Healthcare Demand Risk factors for human disease emergence Plague: A disease which changed the path of human civilization Infectious disease: inextricable linkages between human and ecosystem health The early spread and epidemic ignition of HIV-1 in human populations Pandemic potential of a strain of influenza A (H1N1): early findings Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus The proximal origin of SARS-CoV-2 A review of zoonotic infection risks associated with the wild meat trade in Malaysia Emerging infectious diseases of wildlife--threats to biodiversity and human health China: Clamp down on violations of wildlife trade ban Poaching is Not One Big Thing Parker, and one anonymous reviewer for editorial comments. Such answers are urgent not only for human health but also for conservation.
    keywords: covid-19
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        item: #4013 of 7819
          id: cord-304356-jyp9gjh9
      author: Grant, Rogan A.
       title: Alveolitis in severe SARS-CoV-2 pneumonia is driven by self-sustaining circuits between infected alveolar macrophages and T cells
        date: 2020-08-05
       words: 7464
      flesch: 38
     summary: We performed single cell RNA-Seq in 5 bronchoalveolar lavage fluid samples collected from patients with severe COVID-19 within 48 hours of intubation. Single cell RNA-Seq of flow-sorted BAL cells:
    keywords: alveolar; analysis; bal; cells; controls; cov-2; covid-19; data; figure; flow; infection; macrophages; patients; pneumonia; rna; samples; sars; seq; type
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        item: #4014 of 7819
          id: cord-304379-4mfyxp6h
      author: Wang, Jin
       title: Mathematical models for COVID-19: applications, limitations, and potentials
        date: 2020-06-25
       words: 1565
      flesch: 25
     summary: Mathematical epidemic models are well positioned to incorporate the economic impact of COVID-19, to quantify the interaction of epidemiological and economic factors, and to suggest an optimal balance between the pandemic control and economic development. Machine learning and other artificial intelligence techniques can complement and improve mathematical epidemic models by taking advantage of the large data sets currently available, including epidemic, genetic, demographic, geospatial and mobility data, the scale of which is typically far beyond the applicability of a standard mathematical model.
    keywords: covid-19; modeling; models; transmission
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        item: #4015 of 7819
          id: cord-304388-pth2d40p
      author: Lai, Chih-Cheng
       title: Asymptomatic carrier state, acute respiratory disease, and pneumonia due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Facts and myths
        date: 2020-03-04
       words: 4398
      flesch: 46
     summary: However, asymptomatic patients or patients with mild COVID-19 symptoms may not seek health care, nor receive diagnosis, which leads to underestimation of the burden of COVID-19. Second, Zou et al. reported that the viral load detected in asymptomatic patients was similar to that found in symptomatic patients; however, the viral loads from patients with severe diseases were higher than those in patients with mild-to-moderate presentations.
    keywords: cases; china; coronavirus; cov-2; covid-19; disease; patients; pneumonia; sars
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        item: #4016 of 7819
          id: cord-304399-7t2mu13s
      author: Wynne, Keona Jeane
       title: Dying individuals and suffering populations: applying a population-level bioethics lens to palliative care in humanitarian contexts: before, during and after the COVID-19 pandemic
        date: 2020-06-19
       words: 12083
      flesch: 40
     summary: Based on this logic, if human and material resources are scarce, those patients triaged as expectant will not be allocated palliative care resources in order to maximise the quality life years or utility for individuals for whom curative interventions are an option. key: cord-304399-7t2mu13s authors: Wynne, Keona Jeane; Petrova, Mila; Coghlan, Rachel title: Dying individuals and suffering populations: applying a population-level bioethics lens to palliative care in humanitarian contexts: before, during and after the COVID-19 pandemic date: 2020-06-19 journal: J Med Ethics DOI: 10.1136/medethics-2019-105943 sha: doc_id: 304399 cord_uid: 7t2mu13s BACKGROUND: Humanitarian crises and emergencies, events often marked by high mortality, have until recently excluded palliative care—a specialty focusing on supporting people with serious or terminal illness or those nearing death.
    keywords: bioethics; care; covid-19; crises; dying; emergencies; emergency; euthanasia; groups; guide; health; level; life; palliative; pandemic; patients; population; resources; response
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        item: #4017 of 7819
          id: cord-304418-k9owyolj
      author: Le Maréchal, M.
       title: COVID-19 in clinical practice: a narrative synthesis
        date: 2020-09-29
       words: 6303
      flesch: 43
     summary: Thromboembolic complications Several works have described the high incidence in COVID-19 patients of both venous and arterial thromboembolic diseases. Cardiac injuries have been described in COVID-19 patients.
    keywords: cases; china; coronavirus; covid-19; days; disease; group; infection; patients; remdesivir; sars; study; syndrome; treatment; viral
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        item: #4018 of 7819
          id: cord-304429-qmcrvufu
      author: Deepmala,
       title: Analysis and prediction of Covid-19 spreading through Bayesian modelling with a case study of Uttar Pradesh, India
        date: 2020-08-31
       words: 3288
      flesch: 56
     summary: In Figure 1 , we plotted the bar graphs for daily confirmed cases, daily deceased cases and daily recovered cases, and the scatter plot for the cumulative confirmed cases, cumulative deceased cases, and cumulative recovered cases of COVID-19 for some 4 All rights reserved. Tables 4, 5, and 6 represent the Bayesian estimates, standard error of the estimates, and R 2 for the logistic and Gompertz models fitted to the cumulative confirmed cases, cumulative deceased cases and cumulative recovered cases of COVID-19 in UP respectively.
    keywords: cases; covid-19; india; models; number
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        item: #4019 of 7819
          id: cord-304450-1ub3xzsv
      author: Ralph, Paul
       title: Pandemic programming: How COVID-19 affects software developers and how their organizations can help
        date: 2020-09-14
       words: 10250
      flesch: 46
     summary: However, existing research on developer productivity is rife with construct validity problems. Examining relationships between multiple health risk behaviors, well-being, and productivity Mental health of people in Australia in the first month of COVID-19 restrictions: a national survey An empirical evaluation of alternative methods of estimation for confirmatory factor analysis with ordinal data Octoverse spotlight: An analysis of developer productivity, work cadence, and collaboration in the early days of covid-19 Bayesian data analysis in empirical software engineering research How do you feel, developer?
    keywords: analysis; covid-19; data; developers; disaster; e.g.; et al; fear; home; model; pandemic; people; productivity; questionnaire; research; software; variables; wellbeing; working
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        item: #4020 of 7819
          id: cord-304474-hfv43e9m
      author: Marchese, Valentina
       title: Strongyloides infection manifested during immunosuppressive therapy for SARS-CoV-2 pneumonia
        date: 2020-09-10
       words: 2395
      flesch: 34
     summary: Pneumonia: a systematic review of the literature Potential benefits of precise corticosteroids therapy for severe 2019-nCoV pneumonia A retrospective cohort study of methylprednisolone therapy in severe patients with COVID-19 pneumonia Clinical characteristics of 225 patients with COVID-19 in a tertiary Hospital near Wuhan Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 Pneumonia in Wuhan Dexamethasone in hospitalized patients with Covid-19-preliminary report Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: a single center Tocilizumab in patients with severe COVID-19: a retrospective cohort study ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Soluble immune effector molecules [II]: agents targeting interleukins, immunoglobulins and complement factors) To date, no case of strongyloidiasis related to severe COVID-19 treatment has been reported.
    keywords: covid-19; infection; patients; strongyloides; strongyloidiasis; tocilizumab; treatment
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        item: #4021 of 7819
          id: cord-304479-uxp1kg86
      author: Goodarzi, Pedram
       title: Coronavirus disease 2019 (COVID-19): Immunological approaches and emerging pharmacologic treatments
        date: 2020-08-08
       words: 8115
      flesch: 35
     summary: Furthermore, there are some open clinical trials for the therapeutic assessment of methylprednisolone on COVID-19 patients [57] . [58] , shows that at least six different published studies on the effect of corticosteroids on COVID-19 patients.
    keywords: antiviral; cells; convalescent; coronavirus; cov-2; covid-19; disease; human; infection; patients; plasma; pneumonia; remdesivir; sars; study; therapy; treatment
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        item: #4022 of 7819
          id: cord-304490-q9ab1pji
      author: Iqbal, Najaf
       title: Nexus between COVID-19, temperature and exchange rate in Wuhan City: New findings from Partial and Multiple Wavelet Coherence
        date: 2020-04-22
       words: 3774
      flesch: 47
     summary: In this uncertain situation where literature is inconclusive about the role of temperature in the covid-19 spread, we attempt to analyze the number of daily new covid-19 cases and average daily temperature in this regard. Weather is found to be associated with the daily number of covid-19 cases in the Indonesian capital city of Jakarta also (Tosepu et al., 2020) .
    keywords: coherence; covid-19; exchange; rate; temperature; wavelet; wuhan
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        item: #4023 of 7819
          id: cord-304495-j3kh7tou
      author: Ohnleiter, Thomas
       title: Organisation d’un service de radiothérapie pendant l’épidémie de COVID-19 : expérience du centre hospitalier de Mulhouse
        date: 2020-04-17
       words: 2913
      flesch: 47
     summary: key: cord-304495-j3kh7tou authors: Ohnleiter, Thomas; Piot, Luc; Rogenmuser, Agathe; Noirclerc, Monique; Hamlaoui, Rabah; Grandgirard, Alain title: Organisation d’un service de radiothérapie pendant l’épidémie de COVID-19 : expérience du centre hospitalier de Mulhouse date: 2020-04-17 journal: Cancer Radiother DOI: 10.1016/j.canrad.2020.04.002 sha: doc_id: 304495 cord_uid: j3kh7tou Résumé L’épidémie de COVID-19 continue de croître de manière exponentielle dans notre pays. Organisation d'un service de radiothérapie pendant l'épidémie de COVID- Thomas Épidémie ; COVID-19 ; organisation ; service ; radiothérapie ; patient Keywords Epidemic; COVID-19; Organization; Department; Radiotherapy; Patient Résumé L'épidémie de COVID-19 continue de croître de manière exponentielle dans notre pays.
    keywords: covid-19; dans; des; les; patients; pour; service; sont
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        item: #4024 of 7819
          id: cord-304526-hoybp1h6
      author: Kwon, Ki Tae
       title: Drive-Through Screening Center for COVID-19: a Safe and Efficient Screening System against Massive Community Outbreak
        date: 2020-03-16
       words: 1486
      flesch: 48
     summary: Herein, we present the overall concept, advantages, and limitations of the COVID-19 DT screening centers. At DT screening centers, around 100 tests can be done per day and about four to eight persons are required depending on the design of workflow.
    keywords: centers; covid-19; screening; testees
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        item: #4025 of 7819
          id: cord-304550-6j1pb1pu
      author: Yongchen, Zhang
       title: Different longitudinal patterns of nucleic acid and serology testing results based on disease severity of COVID-19 patients
        date: 2020-05-02
       words: 2034
      flesch: 36
     summary: The dynamic profile of viral replication and shedding along with viral antigen specific antibody responses among COVID-19 patients started to be reported but there is no consensus on their patterns. The dynamic profile of viral replication and shedding along with viral antigen specific antibody responses among COVID-19 patients started to be reported [2] but there is no consensus on their patterns.
    keywords: antibody; covid-19; patients; responses; sars
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        item: #4026 of 7819
          id: cord-304573-3nhglbw4
      author: Bola, Sumrit
       title: COVID-19 and the return to head and neck outpatient activity in the United Kingdom: what is the new normal?
        date: 2020-11-06
       words: 3407
      flesch: 46
     summary: Realising that some NHS Trust may have remote sites for outpatient clinics, entries were only excluded from the study if the place of work and data entry were identical. All otolaryngology survey responders were still performing flexible nasendoscopy (FNE) in outpatient clinic whilst 5 non-otolaryngologist reported that FNE was no longer performed due to safety concerns or an unsuitable room.
    keywords: clinic; nasendoscopy; outpatient; patients; responders; room
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        item: #4027 of 7819
          id: cord-304576-ds3udegk
      author: Sommerstein, Rami
       title: Coronavirus Disease 2019 (COVID‐19): Do Angiotensin‐Converting Enzyme Inhibitors/Angiotensin Receptor Blockers Have a Biphasic Effect?
        date: 2020-04-01
       words: 1461
      flesch: 37
     summary: Several demographic characteristics are associated with increased ACE2 expression, such as older age and male sex. Unfortunately, the European Centre for Disease Prevention and Control does not record any previous drugs in its data collection on COVID-19 patients.
    keywords: ace2; angiotensin; covid-19; enzyme; patients
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        item: #4028 of 7819
          id: cord-304601-e6qlx1r6
      author: Garcez, Flavia Barreto
       title: Delirium and adverse outcomes in hospitalized patients with COVID‐19.
        date: 2020-08-24
       words: 3486
      flesch: 36
     summary: We found that even after these adjustments, delirium remained an independent predictor of adverse outcomes in the hospital, underlining its role as a prognostic marker in COVID-19 patients. We identified delirium occurrence using the Chart‐based Delirium Identification Instrument (CHART‐DEL).
    keywords: article; care; covid-19; delirium; hospital; outcomes; patients; rights
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        item: #4029 of 7819
          id: cord-304603-u7cph27q
      author: Chen, Shi
       title: Capped borrower credit risk and insurer hedging during the COVID-19 outbreak
        date: 2020-09-02
       words: 1717
      flesch: 55
     summary: This The reinsurance decision in life insurance firms: an empirical test of the risk-bearing hypothesis Coronavirus disease 2019 (COVID-19). Moreover, the Board of Governors of the Federal Reserve System (2020) states that the regulators encourage financial institutions to work constructively with borrowing firms affected by the COVID-19 outbreak.
    keywords: borrowing; insurance; insurer; rate
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        item: #4030 of 7819
          id: cord-304610-6o3hydg6
      author: Odeyemi, Festus Ayotunde
       title: Gauging the laboratory responses to coronavirus disease (COVID‐19) in Africa
        date: 2020-08-27
       words: 2320
      flesch: 41
     summary: The critical roles of laboratory testing cannot be overemphasised in the prevention and management of infectious diseases outbreak (Bedford et al., 2020) . NCDC also developed a framework for incorporation of up to high throughput HIV molecular testing laboratories, which are capable of raising national capacity to a minimum of 5,000 tests per day (NCDC, 2020a) .
    keywords: africa; coronavirus; covid-19; disease; laboratory; south; testing
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        item: #4031 of 7819
          id: cord-304636-houm2zcu
      author: Guillan, Marta
       title: Unusual simultaneous cerebral infarcts in multiple arterial territories in a COVID-19 patient
        date: 2020-06-09
       words: 1091
      flesch: 32
     summary: The bottom row images depict axial T2 gradient echo sequences with blooming Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study COVID-19-associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features Characteristics of ischaemic stroke associated with COVID-19 Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Low Diagnostic Yield of Routine Cerebrospinal Fluid Analysis in Juvenile Stroke Central nervous system vasculitis associated with hepatitis C virus infection: a brain MRI-supported diagnosis Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis Infections causing stroke or strokelike syndromes All patients in the stroke unit have signed an informed consent to collect and use their anonymised data for research purposes. Previous studies carried out in stroke patients showed a variable range of reactive pleocytosis up to 64 Mpt/L cell and nonspecific proteins up to 1507 mg/L in CSF
    keywords: cases; covid-19; patients; stroke
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        item: #4032 of 7819
          id: cord-304656-v0fyb161
      author: Balayla, J.
       title: Prevalence Threshold and Temporal Interpretation of Screening Tests: The Example of the SARS-CoV-2 (COVID-19) Pandemic
        date: 2020-05-22
       words: 2131
      flesch: 48
     summary: Herein, we use differential 71 equations to assess the geometry of screening curves and aim to describe the prevalence 72 threshold point beyond which the PPV of various COVID-19 screening tests declines 73 most acutely. In other 133 words, we would expect a sharp increase in the number of false positive screening tests, 134 in turn falsely increasing the estimated prevalence of disease.
    keywords: covid-19; disease; preprint; prevalence; screening
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        item: #4033 of 7819
          id: cord-304664-rha9pwob
      author: Liu, N.
       title: High rate of increased level of plasma Angiotensin II and its gender difference in COVID-19: an analysis of 55 hospitalized patients with COVID-19 in a single hospital, WuHan, China
        date: 2020-05-01
       words: 1910
      flesch: 53
     summary: This study showed a significant difference in the severity of COVID-19 in the elevated AngII group, and the severity of COVID-19 was a risk factor of increased AngII level. In addition, CD4/CD8 cells ratio was a risk factor of increased AngII level.
    keywords: angii; angiotensin; covid-19; level; patients
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        item: #4034 of 7819
          id: cord-304746-7yzybukk
      author: Li, Xinye
       title: Cardiac injury associated with severe disease or ICU admission and death in hospitalized patients with COVID-19: a meta-analysis and systematic review
        date: 2020-07-28
       words: 4590
      flesch: 42
     summary: CONCLUSIONS: COVID-19 patients with elevated TnI levels are at significantly higher risk of severe disease, ICU admission, and death. [Image: see text] Conclusions: COVID-19 patients with elevated TnI levels are at significantly higher risk of severe disease, ICU admission, and death.
    keywords: cardiac; covid-19; disease; icu; icu admission; levels; non; patients
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        item: #4035 of 7819
          id: cord-304766-h9kuytuf
      author: Lei, Hao
       title: Non-pharmaceutical interventions used to control COVID-19 reduced seasonal influenza transmission in China
        date: 2020-09-08
       words: 1761
      flesch: 40
     summary: The reduction of 64% is significantly higher than the reported efficiency of single interventions used against influenza epidemics in the past, such as school closure (16-18% reduction of seasonal influenza cases) Results show that the incidence rate of seasonal influenza reduced by 64% in 2019/20 (p&0.001).
    keywords: china; covid-19; influenza; npis; number
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        item: #4036 of 7819
          id: cord-304780-lbq70q11
      author: Han, Changwoo
       title: Decrease in Ambient Fine Particulate Matter during COVID-19 Crisis and Corresponding Health Benefits in Seoul, Korea
        date: 2020-07-22
       words: 5566
      flesch: 45
     summary: Future studies with daily mortality data are needed to verify our study estimates. We may need to verify our study findings by observing the PM 2.5 levels after the COVID-19 crisis and conducting studies with a full set of daily mortality data.
    keywords: april; covid-19; data; exposure; january; mortality; seoul
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        item: #4037 of 7819
          id: cord-304791-wv4qu9xm
      author: Carfora, Vincenzo
       title: Anticoagulant treatment in COVID-19: a narrative review
        date: 2020-08-18
       words: 3579
      flesch: 34
     summary: To view a copy of this licence, visit http://creat iveco mmons .org/licen ses/by/4.0/. Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2) Outcomes in patients with hyperglycemia affected by COVID-19: can we do more on glycemic control? Lille ICU Haemostasis COVID-19 group (2020) Pulmonary embolism in COVID-19 patients: awareness of an increased prevalence Pulmonary post-mortem findings in a large series of COVID-19 cases from Northern Italy Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study D-dimer is associated with severity of coronavirus disease 2019 (COVID-19): a pooled analysis Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Clinical pathology of critical patient with novel coronavirus pneumonia (COVID-19) ESC guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS) Inflammation and thrombosis: the clot thickens Dysregulation of immune response in patients with COVID-19 in Wuhan, China The role of inflammation in venous thromboembolism Proteinase activated receptors in fibroproliferative lung disease Coagulation cascade proteinases in lung injury and fibrosis Will complement inhibition be the new target in treating COVID-19 related systemic thrombosis? Effective treatment of severe COVID-19 patients with tocilizumab Eculizumab treatment in patients with COVID-19: preliminary results from real life ASL Napoli 2
    keywords: activation; cascade; complement; coronavirus; covid-19; disease; patients; pulmonary; sars; state
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        item: #4038 of 7819
          id: cord-304798-j2tyjo1j
      author: Rapkiewicz, Amy V.
       title: Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series
        date: 2020-06-25
       words: 5322
      flesch: 37
     summary: A recent autopsy series of COVID-19 cases incorporating endothelial electron microscopy demonstrated ultrastructural endothelial damage and increased angiogenesis as compared to cases of fatal influenza, with differential regulation of genes related to angiogenesis and inflammation [24] . Troponin elevation is common in COVID-19 patients and is associated with increased risk of death
    keywords: cardiac; cases; covid-19; disease; heart; megakaryocytes; patients; platelet; pulmonary; series; thrombi; thrombosis
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        item: #4039 of 7819
          id: cord-304802-44m7u1oz
      author: Settersten, Richard A.
       title: Understanding the Effects of COVID-19 Through a Life Course Lens
        date: 2020-07-22
       words: 11407
      flesch: 42
     summary: Fathers may be more present and involved in family life, especially in contexts without paternal leave. Increased work at home can colonize family life.
    keywords: children; consequences; course; covid-19; effects; family; health; life; life course; pandemic; people; r n; term; time; u r; work
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        item: #4040 of 7819
          id: cord-304813-10n1ol1g
      author: Piccolo, Vincenzo
       title: Chilblain‐like lesions during the COVID‐19 pandemic: should we really worry?
        date: 2020-06-04
       words: 246
      flesch: 41
     summary: Available at Clinical characteristics of coronavirus disease 2019 in China Cutaneous manifestations in COVID-19: a first perspective Chilblain-like lesions during COVID-19 epidemic: a preliminary study on 63 patients key: cord-304813-10n1ol1g authors: Piccolo, Vincenzo; Neri, Iria; Manunza, Francesca; Mazzatenta, Carlo; Bassi, Andrea title: Chilblain‐like lesions during the COVID‐19 pandemic: should we really worry? date: 2020-06-04 journal: Int J Dermatol DOI: 10.1111/ijd.14993 sha: doc_id: 304813 cord_uid: 10n1ol1g nan
    keywords: covid-19
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        item: #4041 of 7819
          id: cord-304838-r9w8milu
      author: Olaseni, Abayomi O.
       title: Psychological distress experiences of Nigerians during Covid-19 pandemic; the gender difference
        date: 2020-12-31
       words: 4999
      flesch: 34
     summary: Against this backdrop, it was expected that females should indicate the higher experience of psychological distress but our study found no substantial variation between male and females' experiences on psychological distresses during COVID-19 pandemic, though articles and studies have contrary opinions. key: cord-304838-r9w8milu authors: Olaseni, Abayomi O.; Akinsola, Olusola S.; Agberotimi, Samson F.; Oguntayo, Rotimi title: Psychological distress experiences of Nigerians during Covid-19 pandemic; the gender difference date: 2020-12-31 journal: Social Sciences & Humanities Open DOI: 10.1016/j.ssaho.2020.100052 sha: doc_id: 304838 cord_uid: r9w8milu This study examine the psychological distress experience of Nigerians during the COVID-19 pandemic, across gender.
    keywords: covid-19; depression; health; insomnia; nigeria; pandemic; study; symptoms
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        item: #4042 of 7819
          id: cord-304872-hnxmtbrf
      author: Lv, Hao
       title: Prevalence and recovery time of olfactory and gustatory dysfunctions of hospitalized patients with COVID‑19 in Wuhan, China
        date: 2020-09-17
       words: 3437
      flesch: 51
     summary: Patients with COVID-19 and OD and/or GD had significantly higher rates of cardiovascular disease than patients without OD and/or GD (p = 0.002). Patients under 18 years of age, patients with a history of cognitive disorders, and patients with OD and/or GD known before the epidemic.
    keywords: covid-19; olfactory; patients
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        item: #4043 of 7819
          id: cord-304895-fw7qt571
      author: Belhouideg, Soufiane
       title: Impact of 3D printed medical equipment on the management of the Covid19 pandemic
        date: 2020-06-22
       words: 2573
      flesch: 48
     summary: The role of additive manufacturing and antimicrobial polymers in the COVID-19 pandemic A review of open source ventilators for COVID-19 and future pandemics Pandemic ventilator' could offer solution in potential 'worst case' coronavirus scenario Open source database and website to provide free and open access to inactive U.S. patents in the public domain Ventilator-induced lung injury Ventilator-induced lung injury Ventilator-induced lung injury: the anatomical and physiological framework Mechanical power and development of ventilator-induced lung injury The Ventilator Book Principles and Practice of Mechanical Ventilation Mechanical ventilation: state of the art Development of field portable ventilator systems for domestic and military emergency medical response A new compact and low-cost respirator concept for one way usage Prototyping of artificial respiration machine using AMBU bag compression Design and prototyping of a low-cost portable mechanical ventilator A low oxygen consumption pneumatic ventilator for emergency construction during a respiratory failure pandemic How to cite this article: Belhouideg S. Impact of 3D printed medical equipment on the management of the Covid19 pandemic key: cord-304895-fw7qt571 authors: Belhouideg, Soufiane title: Impact of 3D printed medical equipment on the management of the Covid19 pandemic date: 2020-06-22 journal:
    keywords: covid-19; equipment; pandemic; printing; source; ventilator
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        item: #4044 of 7819
          id: cord-304898-he57l0y7
      author: Belghmaidi, Sarah
       title: Third Cranial Nerve Palsy Presenting with Unilateral Diplopia and Strabismus in a 24-Year-Old Woman with COVID-19
        date: 2020-10-15
       words: 1673
      flesch: 45
     summary: Ophthalmological manifestations of COVID-19 are rare compared with the typical clinical features, which include fever, dry cough, shortness of breath, myalgia, and fatigue, which are seen in most COVID-19 pneumonia patients [3] . Clinical characteristics of coronavirus disease 2019 in China A case of COVID-19 pneumonia in a young male with full body rash as a presenting symptom Coronavirus disease (COVID-19) -World Health Organization SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications Features of anosmia in COVID-19 Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China Evidence of the COVID-19 virus targeting the CNS: Tissue distribution, host-virus interaction, and proposed neurotropic mechanisms COVID-19, SARS and MERS:
    keywords: coronavirus; covid-19; days; nerve; palsy
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        item: #4045 of 7819
          id: cord-304925-9gvx3swf
      author: Xie, Zhixiang
       title: Spatial and temporal differentiation of COVID-19 epidemic spread in mainland China and its influencing factors
        date: 2020-07-14
       words: 4777
      flesch: 34
     summary: Liu et al. (2020c) used the statistical analysis method to analyze the temporal and spatial J o u r n a l P r e -p r o o f characteristics and the transmission path of the COVID-19 epidemic in Zhuhai, revealing that the input from the epidemic area and family gatherings were the causes of epidemic spread. (4) In relation to data sources, the data of COVID-19 cases can be obtained very easily; however, there are great difficulties in obtaining environmental and socio-economic data related to the epidemic spread, which is why current researches lag behind in the driving J o u r n a l P r e -p r o o f mechanism of epidemic spread.
    keywords: covid-19; epidemic; epidemic spread; factors; population; rate; spread
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        item: #4046 of 7819
          id: cord-304928-qcwtgx2b
      author: Pasini, Elena
       title: EEG findings in COVID-19 related encephalopathy
        date: 2020-07-18
       words: 1149
      flesch: 44
     summary: Pay more attention to EEG in COVID-19 pandemic The Emerging Spectrum of COVID-19 Neurology: Clinical, Radiological and Laboratory Findings Clinical and imaging correlates of EEG patterns in hospitalized patients with encephalopathy COVID-19 associated encephalopathy: Indeed, EEG in acute encephalopathies may reveal different degrees of background slowing, with or without triphasic waves and FIRDA and these patterns are believed to reflect an underlying structural or metabolic disorder; however, there is limited evidence linking specific EEG abnormalities with plausible causative factors.
    keywords: activity; eeg; patients
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        item: #4047 of 7819
          id: cord-304946-fs02dxg5
      author: Brochez, L.
       title: Recommendations for skin cancer consultation and surgery during COVID‐19 pandemic
        date: 2020-08-12
       words: 1062
      flesch: 41
     summary: Medical doctors were faced with prioritization of non-COVID19 medical problems in order to reduce potential exposures and to mobilize staff and resources for COVID-19 care. key: cord-304946-fs02dxg5 authors: Brochez, L.; Baurain, J.F.; Del Marmol, V.; Nikkels, A.; Kruse, V.; Sales, F.; Stas, M.; Van Laethem, A.; Garmyn, M. title: Recommendations for skin cancer consultation and surgery during COVID‐19 pandemic date: 2020-08-12 journal: J Eur Acad Dermatol Venereol DOI: 10.1111/jdv.16772 sha: doc_id: 304946 cord_uid: fs02dxg5 nan As a result of the outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and government lockdown measures, healthcare systems were challenged worldwide.
    keywords: covid-19; covid19; mask; pandemic
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        item: #4048 of 7819
          id: cord-304956-zqm5fl38
      author: Vinayachandran, Divya
       title: Is gustatory impairment the first report of an oral manifestation in COVID‐19?
        date: 2020-05-18
       words: 622
      flesch: 40
     summary: Similarly, investigations like whole mouth test, spatial taste test (tongue mapping) can be employed to check taste disorders (Ambaldhage, Puttabuddi, Nunsavath, & Tummuru, 2014) . It was also suggested in a recent study that the Pennsylvanian smell identification test can be used for assessing olfactory disturbances in COVID-19 cases (Giacomelli et al., 2020) .
    keywords: patients; taste
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        item: #4049 of 7819
          id: cord-304966-w2voi8en
      author: Cummings, Cori
       title: Blacks Are Less Likely to Present With Strokes During the COVID-19 Pandemic: Observations From the Buckle of the Stroke Belt
        date: 2020-08-17
       words: 1585
      flesch: 49
     summary: There was no difference in baseline features; however, Black patients were less likely to present with strokes during the pandemic (13.9% versus 29%, P≤0.002). The impact seems to disproportionately affect Black patients.
    keywords: covid-19; pandemic; patients; stroke
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        item: #4050 of 7819
          id: cord-304983-u2yag4gf
      author: Albani, Filippo
       title: Thromboprophylaxis with enoxaparin is associated with a lower death rate in patients hospitalized with SARS-CoV-2 infection. A cohort study
        date: 2020-10-05
       words: 3851
      flesch: 36
     summary: Since the usefulness of enoxaparin in improving the clinical outcome in COVID-19 patients seems consistent, and its use is already routine in many hospital wards and intensive care units, there is urgent need for randomized trials to evaluate their clinical efficacy and safety in patients with infection from SARS-CoV-2. [4, 19] , which can aggravate the ventilation perfusion mismatch and can be the physiopathological explanation for the profound hypoxia in COVID-19 patients.
    keywords: admission; covid-19; enoxaparin; hospital; mortality; patients; study; treatment
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        item: #4051 of 7819
          id: cord-304996-st1nn3pc
      author: Baggiani, Angelo
       title: Preparedness and Response to the COVID-19 Emergency: Experience from the Teaching Hospital of Pisa, Italy
        date: 2020-10-09
       words: 3430
      flesch: 45
     summary: From 19 March, several clinical wards and operating rooms, located in different hospital units, have been repurposed to realize 160 additional beds in COVID-19 clinical wards (COVID-19 area 1-2-3-4). In ICUs of COVID-19 area, a total of 83 beds were divided into five ICUs (ICUs 1-5).
    keywords: april; area; beds; care; cases; covid-19; health; hospital; patients; tuscany
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        item: #4052 of 7819
          id: cord-305000-yx4fu9ds
      author: Riley, Matthew J.
       title: Hereditary haemochromatosis, haemophagocytic lymphohistiocytosis and COVID-19
        date: 2020-11-01
       words: 2260
      flesch: 38
     summary: Secondary effects include the partial or complete loss of hepcidin production resulting in reduced macrophage iron storage and increased iron in the bloodstream [3] . key: cord-305000-yx4fu9ds authors: Riley, Matthew J.; Rory Hicks, Scott; Irvine, Sharon; Blanchard, Tom J.; Britton, Edward; Shawki, Howida; Sajid Pervaiz, Muhammad; Fletcher, Tom title: Hereditary haemochromatosis, haemophagocytic lymphohistiocytosis and COVID-19 date: 2020-11-01 journal: Clin Infect Pract DOI: 10.1016/j.clinpr.2020.100052 sha: doc_id: 305000 cord_uid: yx4fu9ds Background Syndromes of iron overload have been shown to increase the risk of severe clinical disease in viral infections.
    keywords: covid-19; hfe; hlh; iron; patients; syndrome
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        item: #4053 of 7819
          id: cord-305025-pqye1ebh
      author: Sharifi, Majid
       title: Rapid diagnostics of coronavirus disease 2019 in early stages using nanobiosensors: challenges and opportunities
        date: 2020-09-28
       words: 3594
      flesch: 17
     summary: In conclusion, it can be deduced that as rapid COVID-19 detection infection can play a vital role in disease control and treatment, this review may be of great help for controlling the COVID-19 outbreak by providing some necessary information for the development of portable, accurate, selectable and simple nanobiosensors. press2009 Molecular diagnosis of influenza Sensitive 650 in situ hybridization with catalyzed reporter deposition, streptavidin-Nanogold, and silver 651 acetate autometallography: detection of single-copy human papillomavirus electrochemical DNA biosensor for detecting hepatitis A virus A versatile DNA detection scheme based on the 657 quenching of fluorescent silver nanoclusters by MoS 2 nanosheets: application to aptamer-658 based determination of hepatitis B virus and of dopamine The field effect transistor DNA biosensor based on ITO nanowires in label-661 free hepatitis B virus detecting compatible with CMOS technology chitosan and MWCNT for the determination of daclatasvir: a hepatitis C 665 antiviral drug A smart nanosensor for the detection of human immunodeficiency virus and associated 668 cardiovascular and arthritis diseases using functionalized graphene-based transistors Two types of nanoparticle-based bio-barcode amplification assays to detect HIV-1 p24 672 antigen Copper sulfide nanoplates as nanosensors for fast, 674 sensitive and selective detection of DNA A novel electrochemical DNA biosensor for Ebola virus detection Field-678 effect transistor biosensor for rapid detection of Ebola antigen Colorimetric detection of influenza A (H1N1) virus by a peptide-functionalized 681 polydiacetylene (PEP-PDA) nanosensor Electrophoresis-enhanced detection of 683 deoxyribonucleic acids on a membrane-based lateral flow strip using avian influenza H5 684 genetic sequence as the model Novel magnetic 686 relaxation nanosensors: an unparalleled spin on influenza diagnosis Direct acoustic profiling of 689 DNA hybridisation using HSV type 1 viral sequences Multiplexed colorimetric detection of 691 Kaposi's sarcoma associated herpesvirus and Bartonella DNA using gold and silver 692 nanoparticles Portable bioactive 694 paper based genosensor incorporated with Zn-Ag nanoblooms for herpes detection at the 695 point-of-care Reactive carbon nano-onion modified glassy 697 carbon surfaces as DNA sensors for human papillomavirus oncogene detection with enhanced 698 sensitivity Impedimetic biosensor for the DNA of the human papilloma virus based on the use of gold 701 nanosheets An ultrasensitive label free 703 human papilloma virus DNA biosensor using gold nanotubes based on nanoporous 704 polycarbonate in electrical alignment Plasmonic and chiroplasmonic nanobiosensors based on gold 708 nanoparticles Cancer diagnosis using nanomaterials based electrochemical 711 nanobiosensors Chapter 4 -Nanobiosensors for virus detection in the environment Development of point-of-care 716 nanobiosensors for breast cancers diagnosis Nanobiosensor: Current Trends and Applications Electrochemical virus detections with nanobiosensors Nanosensors for Smart Cities Recent trends in rapid detection of influenza infections by bio and nanobiosensor An alternative medical diagnosis method: 726 Biosensors for virus detection Coronavirus disease 2019 (COVID-19): situation report Covid-19 in Critically Ill Patients in the 730 Seattle Region-Case Series Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, The 733 lancet Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia 736 in Wuhan, China: a descriptive study Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-739 infected pneumonia in Wuhan, China Clinical 741 course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: 742 a single-centered, retrospective, observational study Analysis of CT 747 features of 15 children with 2019 novel coronavirus infection, Zhonghua er ke za zhi= 748 Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China coronavirus disease 2019 (COVID-19) in China: a report of 754 1014 cases Clinical characteristics of 2019 novel coronavirus infection in China Clinical 759 characteristics of 25 death cases infected with COVID-19 pneumonia: a retrospective review 760 of medical records in a single medical center A 762 tool to early predict severe 2019-novel coronavirus pneumonia (COVID-19): a multicenter 763 study using the risk nomogram in Wuhan and Guangdong Laboratory Parameters in COVID-19 detection Patients with Positive 766 COVID-19: A systematic review and meta-analysis, Travel medicine and infectious disease Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts' 775 consensus statement Population-scale COVID-19 diagnostics using a compressed 778 barcode space Al-alawneh, COVID-19 Infection Diagnosis: Potential Impact of 780 Isothermal Amplification Technology to Reduce Community Transmission of SARS-CoV-2 Evaluation of COVID-19 RT-qPCR test in 784 multi-sample pools TaqMan probes to increase the sensitivity of 1-step quantitative reverse transcription-PCR: 787 application to the detection of SARS coronavirus RNA as a control for multiplex real-time reverse transcription-PCR detection of influenza 790 virus and severe acute respiratory syndrome coronavirus Detection of 2019 novel coronavirus (2019-nCoV) by 794 real-time RT-PCR Early transmission dynamics in Wuhan, China, of novel coronavirus-infected 797 pneumonia Improved molecular diagnosis of COVID-19 800 by the novel, highly sensitive and specific COVID-19-RdRp/Hel real-time reverse 801 transcription-PCR assay validated in vitro and with clinical specimens Novel coronavirus strain 2019-ncov Co-diagnostics Inc designs test for new coronavirus using coprimer 806 platform Bgi develops real-time fluorescent rt-pcr kit for detecting the 2019 novel 809 coronavirus Altona diagnostics is developing a rt-pcr kit for detection of novel 812 novel coronavirus disease (COVID-19): 815 paving the road for rapid detection and point-of-care diagnostics Rapid Detection of SARS-CoV-2 Using Reverse transcription RT-LAMP method Overcoming the 821 bottleneck to widespread testing: A rapid review of nucleic acid testing approaches for COVID-19 detection Detection of Middle East respiratory syndrome coronavirus using reverse 825 loop-mediated isothermal amplification (RT-LAMP) Development and evaluation of a novel loop-mediated isothermal amplification 829 method for rapid detection of severe acute respiratory syndrome coronavirus Development of Reverse Transcription Loop-mediated Isothermal Amplification (RT-LAMP)
    keywords: coronavirus; cov-2; covid-19; detection; diagnosis; methods; nanobiosensors; novel; pcr; sars
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        item: #4054 of 7819
          id: cord-305044-lrxzeysw
      author: Abbaszadeh-Kasbi, Ali
       title: An Invited commentary on ‘’ Transforming laparoendoscopic surgical protocols during COVID-19 pandemic; big data analytics, resource allocation and operational considerations; a review article’’
        date: 2020-07-15
       words: 357
      flesch: 28
     summary: key: cord-305044-lrxzeysw authors: Abbaszadeh-Kasbi, Ali; Nikzad, Paria title: An Invited commentary on ‘’ Transforming laparoendoscopic surgical protocols during COVID-19 pandemic; big data analytics, resource allocation and operational considerations; a review article’’ date: 2020-07-15 journal: Int J Surg DOI: 10.1016/j.ijsu.2020.07.005 sha: doc_id: 305044 cord_uid: lrxzeysw nan In general, as mentioned in this study and the protocols developed by the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) and the European Association of Endoscopic Laparoscopic cholecystectomy versus mini-laparotomy cholecystectomy: a meta-analysis of randomised control trials Transforming laparoendoscopic surgical protocols during the COVID-19 pandemic big data analytics, resource allocation and operational considerations SAGES and EAES recommendations for minimally invasive surgery during COVID-19 pandemic
    keywords: covid-19; patients
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        item: #4055 of 7819
          id: cord-305048-y42o6exe
      author: Sugimoto, Hiroshi
       title: Chest tube with air leaks is a potential “super spreader” of COVID-19
        date: 2020-06-05
       words: 329
      flesch: 56
     summary: key: cord-305048-y42o6exe authors: Sugimoto, Hiroshi; Kohama, Takuya title: Chest tube with air leaks is a potential “super spreader” of COVID-19 date: 2020-06-05 journal: Am J Infect Control DOI: 10.1016/j.ajic.2020.06.001 sha: doc_id: Further research is required to determine whether chest tubes with air leaks are a source of infectious aerosols.
    keywords: chest
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        item: #4056 of 7819
          id: cord-305057-elglyass
      author: Dutt, Tina
       title: Thromboprophylaxis in COVID-19: Anti-FXa—the Missing Factor?
        date: 2020-08-01
       words: 1375
      flesch: 25
     summary: Interestingly, Middeldorp and colleagues compared ITU patients with ward patients and commented on a much lower rate of venous thromboembolism (VTE) in the latter (6) . The authors suggested that ITU patients may warrant higher thromboprophylaxis dosing such as enoxaparin 40 mg twice daily versus 40 mg once daily (4).
    keywords: anti; covid-19; patients; thromboprophylaxis
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        item: #4057 of 7819
          id: cord-305059-8z54lw2d
      author: Qu, Jie-Ming
       title: Chapter 4 Diagnosis of COVID-19
        date: 2021-12-31
       words: 5057
      flesch: 43
     summary: At present, the problems encountered in virus nucleic acid detection may come from the following: (1) Timing and location malfunction of specimen collection. Currently, there are four recommended assays, including virus isolation and culture, serum-specific antibody detection, virus antigen detection, and nucleic acid detection.
    keywords: acid; cases; cov-2; covid-19; detection; diagnosis; patients; pneumonia; sars; virus
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        item: #4058 of 7819
          id: cord-305068-9qh8vgtc
      author: Pinto Pereira, João
       title: Management of COVID-19 Coagulopathy in a Patient with Severe Haemophilia A
        date: 2020-09-25
       words: 1557
      flesch: 35
     summary: key: cord-305068-9qh8vgtc authors: Pinto Pereira, João; Hantson, Philippe; Gerard, Ludovic; Wittebole, Xavier; Laterre, Pierre-François; Lambert, Catherine; Hermans, Cédric title: Management of COVID-19 Coagulopathy in a Patient with Severe Haemophilia A date: 2020-09-25 journal: Acta Haematol DOI: 10.1159/000510591 sha: doc_id: 305068 cord_uid: 9qh8vgtc A 54-year-old man with a long history of severe haemophilia A treated prophylactically with efmoroctocog alpha (3,000 IU twice weekly) was diagnosed with COVID-19 infection. The diagnosis of COVID-19 infection was rapidly obtained by reverse transcription-polymerase chain reaction (RT-PCR) on the nasopharyngeal swab, and lung computed tomography revealed bilateral ground glass opacities.
    keywords: covid-19; haemophilia; icu; infection; patients
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        item: #4059 of 7819
          id: cord-305073-8301zqj9
      author: Alhakeem, Ayat
       title: Case Report: COVID-19–Associated Bilateral Spontaneous Pneumothorax—A Literature Review
        date: 2020-07-14
       words: 1395
      flesch: 40
     summary: Review of the literature shows 18 case reports describing COVID-19 patients with spontaneous pneumothorax. This association could be secondary to underlying undiagnosed Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China Diagnosis and treatment of severe COVID-19 complicated with spontaneous pneumothorax: a case report SARS-CoV-2 infection associated with spontaneous pneumothorax Spontaneous pneumothorax and subcutaneous emphysema in COVID-19 patient: case report A case of spontaneous pneumothorax in COVID-19 pneumonia COVID-19 with spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema COVID-19, chronic obstructive pulmonary disease and pneumothorax: a frightening triad Tension pneumothorax in a patient with COVID-19 Mediastinal emphysema, giant bulla, and pneumothorax developed during the course of COVID-19 pneumonia Spontaneous pneumomediastinum: a probable unusual complication of coronavirus disease 2019 (COVID-19) pneumonia
    keywords: chest; covid-19; disease; pneumothorax
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        item: #4060 of 7819
          id: cord-305076-v56y5nyt
      author: Singh, Parmvir
       title: Disseminated Intravascular Coagulation: A Devastating Systemic Disorder of Special Concern with COVID‐19
        date: 2020-07-23
       words: 2914
      flesch: 39
     summary: 1, 8, 9 They are elevated in 40% of critically ill patients, 80% of trauma patients, and nearly 100% of DIC patients. The hypercoagulable state of DIC results in microvascular occlusion beginning distally and advancing proximally.
    keywords: coagulation; covid-19; dic; fulminans; gangrene; patients; purpura; skin
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        item: #4061 of 7819
          id: cord-305089-y5cdqlze
      author: González-García, Andrés
       title: Successful treatment of severe COVID-19 with subcutaneous anakinra as a sole treatment
        date: 2020-06-22
       words: 1268
      flesch: 33
     summary: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China The immunology of macrophage activation syndrome COVID-19: consider cytokine storm syndromes and immunosuppression Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in severe patients with COVID-19 Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease Induction of proinflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies Current therapeutic options for the main monogenic autoinflammatory diseases and PFAPA syndrome: evidence-based approach and proposal of a practical guide Successful tocilizumab therapy for macrophage activation syndrome associated with adult-onset Still's disease: a case-based review Interleukin-1 receptor blockade is associated with reduced mortality in sepsis patients with features of macrophage activation syndrome: reanalysis of a prior phase III trial Continuous intravenous anakinra infusion to calm the cytokine storm in macrophage activation syndrome After an initial viral phase with fever, coughing and mild upper respiratory tract symptoms, some COVID-19 patients may experience a hyperinflammatory phase manifested with biological changes of a cytokine storm syndrome (with increased levels of ferritin and CRP), which are similar to those observed after chimeric antigen receptor (CAR) Tcell therapy and in haemophagocytic lymphohistiocytosis (HLH), as well as in macrophage activation syndrome (MAS), a secondary HLH form, classically associated with autoimmune or inflammatory conditions [2] .
    keywords: anakinra; covid-19; syndrome
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        item: #4062 of 7819
          id: cord-305110-mujpekyu
      author: Cloud, David H.
       title: Medical Isolation and Solitary Confinement: Balancing Health and Humanity in US Jails and Prisons During COVID-19
        date: 2020-07-06
       words: 2336
      flesch: 32
     summary: By doing so, then all those invested in stopping the spread of COVID-19 in prisons can work together to integrate medically sound, humane forms of medical isolation and quarantine that follow community standards of care rather than punitive forms of solitary confinement to manage COVID-19. 10 Many advocates fear that use of isolation to curb transmission of COVID-19 in correctional facilities will complicate the emerging crisis, as incarcerated people become reluctant to report symptoms for fear of being moved to solitary confinement, those who do report symptoms will be forced to endure an experience known to cause psychological and physical harm, and system-wide unrest will be triggered in institutions where fears about being placed in medical isolation could run rampant.
    keywords: confinement; covid-19; isolation; prisons; quarantine
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        item: #4063 of 7819
          id: cord-305134-s7h6bpof
      author: Mackman, Nigel
       title: Coagulation Abnormalities and Thrombosis in Patients Infected With SARS-CoV-2 and Other Pandemic Viruses
        date: 2020-07-13
       words: 6427
      flesch: 35
     summary: Pulmonary thrombosis and microvascular thrombosis are observed in autopsy studies, and this may contribute to the severe hypoxia observed in COVID-19 patients. It is likely that multiple systems contribute to thrombosis in COVID-19 patients, such as activation of coagulation, platelet activation, hypofibrinolysis, endothelial cell dysfunction, inflammation, neutrophil extracellular traps, and complement.
    keywords: activation; acute; cells; coagulation; coronavirus; covid-19; infection; lung; patients; sars; study; syndrome; thrombosis
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        item: #4064 of 7819
          id: cord-305136-tnvp3n1g
      author: Hauer, Karen E.
       title: The COVID-19 Pandemic as an Imperative to Advance Medical Student Assessment: 3 Areas for Change
        date: 2020-10-07
       words: 3528
      flesch: 29
     summary: Competency-based education in longitudinal integrated clerkships LCME update on medical students, patients, and COVID-19: Acad Med DOI: 10.1097/acm.0000000000003764 sha: doc_id: 305136 cord_uid: tnvp3n1g Conditions caused by the COVID-19 pandemic have disrupted clinical practice and all aspects of medical education.
    keywords: assessment; covid-19; education; learning; medical; outcomes; pandemic; students
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        item: #4065 of 7819
          id: cord-305139-851v2qr3
      author: Peys, Elise
       title: Haemoptysis as the first presentation of COVID-19: a case report
        date: 2020-10-22
       words: 2558
      flesch: 49
     summary: Among COVID-19 patients, fever, cough and fatigue are the most commonly reported clinical symptoms. The role of bronchoscopy in COVID-19 patients during the SARS-CoV-2 pandemic Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
    keywords: case; cov-2; covid-19; haemoptysis; patient; range; reference
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        item: #4066 of 7819
          id: cord-305169-5b4b0qx2
      author: Gao, Liang-qin
       title: In Silico Screening of Potential Chinese Herbal Medicine Against COVID-19 by Targeting SARS-CoV-2 3CLpro and Angiotensin Converting Enzyme II Using Molecular Docking
        date: 2020-07-06
       words: 2586
      flesch: 40
     summary: The STRING database was used to analyze the relationship between drug targets, and the visual analysis was conducted with the help of the Cytoscape 3.5.1 software. According to the optimal binding energy (affinity) of each compound with the 3CL hydrolase and ACE2 converting enzyme, a small molecule database of anti-COVID-19 CM was established.
    keywords: chm; covid-19; drug; flos; forsythiae; fructus; pair; study
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        item: #4067 of 7819
          id: cord-305179-c6d2vym9
      author: Vaid, Shashank
       title: Deep learning COVID-19 detection bias: accuracy through artificial intelligence
        date: 2020-05-27
       words: 2279
      flesch: 46
     summary: One major limitation of training CNNs for COVID-19 detection is the lack of publicly available and expert labeled images. The images were collected from a collection of recently published papers and articles as a global effort to encourage widespread and collaborative research in COVID-19 detection [7, 8] .
    keywords: chest; covid-19; detection; learning; model; scans
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        item: #4068 of 7819
          id: cord-305183-6ixjbbek
      author: Mehrotra, S.
       title: A Model for Supply-Chain Decisions for Resource Sharing with an Application to Ventilator Allocation to Combat COVID-19
        date: 2020-04-06
       words: 4918
      flesch: 52
     summary: The problem of estimating mechanical ventilator demand in the United States during an influenza pandemic was considered in [24] . In the context of ventilator allocation, a conceptual framework for allocating ventilators in a public emergency is proposed in [31] .
    keywords: covid-19; demand; model; patients; preprint; ventilators
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        item: #4069 of 7819
          id: cord-305226-9iedjcr6
      author: Dua, Anisha B
       title: Challenges, collaboration, and innovation in rheumatology education during the COVID-19 pandemic: leveraging new ways to teach
        date: 2020-10-16
       words: 4584
      flesch: 28
     summary: Social media has become a powerful instrument for international collaboration and knowledge and information sharing that supplements traditional learning, and rheumatology medical education has been no exception. This new and exciting format for medical education may have a lasting impact on the field beyond the limits of this pandemic.
    keywords: care; covid-19; education; learners; learning; pandemic; rheumatology; teaching; technology; training
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        item: #4070 of 7819
          id: cord-305262-23qylbmg
      author: Rowan, Neil J.
       title: Unlocking the surge in demand for personal and protective equipment (PPE) and improvised face coverings arising from coronavirus disease (COVID-19) pandemic – Implications for efficacy, re-use and sustainable waste management
        date: 2020-09-10
       words: 9985
      flesch: 31
     summary: Use of artificial intelligence and deep learning could help identify high-risk patients and suggest appropriate types and use of PPE Boṧkoski et al., (2020) Kampf et al. (2020) had also analysed 22 studies of different human coronaviruses where SARS, MERS, HCoV (but not including were efficiently inactivated by disinfection on variety of contact surface using 62 to 71% ethanol, 0.5% hydrogen peroxide, or 0.1% sodium hypocholorite within 1 min of exposure, but survived on untreated surfaces for up to 9 days.
    keywords: cov-2; coverings; covid-19; decontamination; disinfection; efficacy; equipment; et al; face; healthcare; heat; management; masks; n95; pandemic; potential; ppe; respirators; reuse; rowan; sars; use; waste
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        item: #4071 of 7819
          id: cord-305266-fuaq4ujb
      author: Gong, Yue
       title: Early Research on COVID-19: A Bibliometric Analysis
        date: 2020-08-05
       words: 2134
      flesch: 16
     summary: Chin Research advances of novel coronavirus disease (COVID-19) Current status of research on coronavirus Cross-species transmission of the newly identified coronavirus 2019-nCoV Bioinformatics analysis of the 2019 novel coronavirus genome Analysis of myocardial injury in patients with COVID-19 and association between concomitant cardiovascular diseases and severity of COVID-19 Quantifying the association between domestic travel and the exportation of novel coronavirus (2019-nCoV) cases from Wuhan, China in 2020: a correlational analysis Escalating infection control response to the rapidly evolving epidemiology of the coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in Hong Kong Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges Insights into the Recent 2019 Novel Coronavirus (SARS-CoV-2) in Light of Past Human Coronavirus Outbreaks Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China Emerging novel coronavirus (2019-nCoV)-current scenario, evolutionary perspective based on genome analysis and recent developments Cross-species transmission of the newly identified coronavirus 2019-nCoV First respiratory transmitted food borne outbreak? Enteric involvement of coronaviruses: is faecal-oral transmission of SARS-CoV-2 possible? Advances on presymptomatic or asymptomatic carrier transmission of COVID-19. The Coronavirus Study Group 4 (CSG) of the International Committee on Taxonomy of Viruses designated the causative 5 virus as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the disease, 6 which subsequently spread globally, was named coronavirus disease of 2019 7 COVID-19, covering topics such as etiology, diagnosis, epidemiology, treatment, 24 prognosis, nursing, prevention and control, were available in the PubMed and China 25 national knowledge infrastructure (CNKI) databases.
    keywords: 2019; coronavirus; cov-2; covid-19; disease; novel; sars
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        item: #4072 of 7819
          id: cord-305270-vos341i1
      author: Conte, Luana
       title: Targeting the gut–lung microbiota axis by means of a high-fibre diet and probiotics may have anti-inflammatory effects in COVID-19 infection
        date: 2020-06-29
       words: 2459
      flesch: 27
     summary: keywords: anti-inflammatory effects, COVID-19 infection, gut-lung microbiota aixs, high-fibre diet, probiotics, SARS-CoV-2 The fact that ACE2 mutants exhibit altered gut microbial composition, 16 and patients with respiratory infections, including COVID-19 infection, may generally have gut microbial alterations and dysfunction, has led some researchers to link COVID-19 to the gut microbiota. key: cord-305270-vos341i1 authors: Conte, Luana; Toraldo, Domenico Maurizio title: Targeting the gut–lung microbiota axis by means of a high-fibre diet and probiotics may have anti-inflammatory effects in COVID-19 infection date: 2020-06-29 journal: Ther Adv Respir Dis DOI: 10.1177/1753466620937170 sha: doc_id: 305270 cord_uid: vos341i1 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 1 is a 2019 novel coronavirus, which only in the European area has led to more than 300,000 cases with at least 21,000 deaths.
    keywords: coronavirus; covid-19; disease; gut; lung; microbiota; patients; probiotics
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        item: #4073 of 7819
          id: cord-305281-vlsy1ofk
      author: Cuschieri, Sarah
       title: Dealing with COVID-19 in small European island states: Cyprus, Iceland and Malta
        date: 2020-11-12
       words: 1983
      flesch: 49
     summary: In Malta, nursing homes employees were tested for SARS-CoV-2 before Lifting and the re-introduction of COVID-19 restrictions In the beginning of May 2020, Cyprus, Iceland and Malta started to gradually lift the restrictions that were instituted at the beginning of the pandemic. In Cyprus an ICU in Nicosia General Hospital (NGH) was built for the same purposes in case of a high number of COVID-19 cases [8] .
    keywords: cases; covid-19; cyprus; iceland; malta; restrictions
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        item: #4074 of 7819
          id: cord-305283-1bg1ykui
      author: ElSeirafi, Mohamed MA.
       title: Efficacy and safety of tocilizumab in critically ill adults with COVID-19 infection in Bahrain: A report of 5 cases
        date: 2020-06-23
       words: 1917
      flesch: 44
     summary: Tocilizumab: A Review in Rheumatoid Arthritis Clinical outcomes in COVID-19 patients treated with tocilizumab: An individual patient data systematic review The Covid Irccs Tocilizumab for treatment of severe COVID-19 patients: Preliminary results from SMAtteo COvid19 REgistry (SMACORE). We observed in the present study that COVID-19 patients with severe lung injury responded dramatically following the introduction of tocilizumab.
    keywords: covid-19; lung; patient; therapy; tocilizumab
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        item: #4075 of 7819
          id: cord-305286-nbbg511n
      author: Xu, Zihui
       title: The impact of type 2 diabetes and its management on the prognosis of patients with severe COVID‐19
        date: 2020-07-08
       words: 4021
      flesch: 48
     summary: On admission, NEWS2 score of T2DM patients was higher than non-DM patients (Median (IQR), 5(4-8) vs. 5(3-6); It indicated that T2DM patients were more severely ill than non-DM patients on admission.
    keywords: covid-19; diabetes; glucose; patients; t2 dm; treatment
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        item: #4076 of 7819
          id: cord-305297-ync3dhyz
      author: Flanders, W. Dana
       title: The Association of Voter Turnout with County-level COVID-19 Occurrence Early in the Pandemic
        date: 2020-07-01
       words: 4361
      flesch: 45
     summary: We calculated case counts for each of a series of risk periods, ranging in length from 5 to 12 days, as indicated in Tables 3 and 4 . Alternative outcomes: We reasoned that if the association of voter turnout with COVID-19 occurrence in the post-vote period was attributable to uncontrolled confounding, then that association should persist even if we redefined the outcome as cases occurring in risk periods (e.g. in early April) that did not overlap substantially with the time interval of interest (the incubation period plus some allowance for testing and reporting).
    keywords: association; cases; county; covid-19; risk; turnout; voter
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        item: #4077 of 7819
          id: cord-305299-vbhilmve
      author: Santos, C. Sieiro
       title: Determinants of COVID-19 disease severity in patients with underlying rheumatic disease
        date: 2020-07-27
       words: 2944
      flesch: 37
     summary: Studies including inflammatory rheumatic disease patients with COVID-19 are still limited; however, we hope these data can shed some light as to know which of the factors may be associated with an increased mortality. Rheumatic patients should be given special attention regarding COVID-19 infection due to their immunocompromised state resulting from their underlying immune conditions and use of targeted immune-modulating therapies.
    keywords: covid-19; disease; hospital; infection; patients; study; use
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        item: #4078 of 7819
          id: cord-305342-6t5il86c
      author: Zhang, Xiao
       title: Coming back to the normal clinic: how has COVID-19 changed us?
        date: 2020-06-12
       words: 694
      flesch: 46
     summary: Along with the reopening of the city, the number of patients undergoing nuclear medical examinations is gradually increasing. Patients can register and make an appointment online.
    keywords: covid-19; imaging; patients
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        item: #4079 of 7819
          id: cord-305363-4msd8mqo
      author: Roselli, Lucia Reis Peixoto
       title: Utility-Based Multicriteria Model for Screening Patients under the COVID-19 Pandemic
        date: 2020-09-01
       words: 4534
      flesch: 45
     summary: Also, behavioral studies based on the data Computational and Mathematical Methods in Medicine obtained from the physicians' records may be useful for improving the design of decision information systems and their functionalities. [16] conducted a study to show the potential and impact of three approaches in the use of cost-effective analysis in the scope of breast cancer control: targeting specific groups, by comparing disparities; equity weighting, by valuing high and low health gains differently; and multicriteria decision analysis, giving weights for multiple equity and efficient criteria.
    keywords: analysis; cost; decision; icu; model; patient; screening; utility
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        item: #4080 of 7819
          id: cord-305389-n5cppi72
      author: D’Alonzo, Daniele
       title: COVID-19 and pneumonia: a role for the uPA/uPAR system
        date: 2020-06-18
       words: 4856
      flesch: 28
     summary: uPAR binds vitronectin, and multiple cell receptors, such as different types of transmembrane receptor [the formyl peptide receptors (FPRs), integrins, and VEGFR2 [23] ], establishing crosstalk between membrane-bound uPAR and its co-receptors. uPAR interacts with cell membrane receptors, such as integrins, FPRs, and VEGFR2.
    keywords: activator; ards; cell; levels; patients; peptide; plasminogen; receptor; soluble; system; upar; uparant; urokinase
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        item: #4081 of 7819
          id: cord-305397-4dx3q6o6
      author: Ashraf, Muddasir
       title: Seizures Related to Coronavirus Disease (COVID-19): Case Series and Literature Review
        date: 2020-07-24
       words: 1872
      flesch: 53
     summary: We present three cases of COVID-19 patients with seizures. The development of headaches, encephalitis, strokes, and epileptic seizures are among the many neurological symptoms that are manifesting within COVID-19 patients [1] .
    keywords: covid-19; disease; patient; seizures
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        item: #4082 of 7819
          id: cord-305405-me4gebvm
      author: Conway, J.
       title: Characteristics of patients with diabetes hospitalised for COVID-19 infection-a brief case series report
        date: 2020-09-21
       words: 3187
      flesch: 45
     summary: The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) -China Impact of diabetes mellitus on clinical outcomes in patients affected by Covid-19 Outcomes in Patients With Hyperglycemia Affected by COVID-19: Can We Do More on Glycemic Control? Hyperglycaemia on admission to hospital and COVID-19 Negative impact of hyperglycaemia on tocilizumab therapy in Covid-19 patients Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? key: cord-305405-me4gebvm authors: Conway, J.; Gould, A.; Westley, R.; Raju, S.; Oklopcic, A.; Broadbent, A.; Abdelhafiz, AH.; Sinclair, AJ. title: Characteristics of patients with diabetes hospitalised for COVID-19 infection-a brief case series report date: 2020-09-21 journal: Diabetes Res Clin Pract DOI: 10.1016/j.diabres.2020.108460 sha: doc_id: 305405 cord_uid: me4gebvm Objectives Diabetes has been shown to be a risk factor for corona virus disease-2019 (COVID-19) infection.
    keywords: cohort; covid-19; diabetes; infection; patients; risk; study
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        item: #4083 of 7819
          id: cord-305422-t8azymo7
      author: Yi, Ye
       title: COVID-19: what has been learned and to be learned about the novel coronavirus disease
        date: 2020-03-15
       words: 8317
      flesch: 47
     summary: In SARS patients, it has been demonstrated that fever (99%-100%), dry cough (29%-75%), dyspnea (40%-42%), diarrhea (20-25%), and sore throat (13-25%) were the major symptoms and ventilation support was required for approximately 14%-20% of the patients [45] . Cardiac events were also the main reason for death in SARS patients [55, 65, 99] .
    keywords: acute; cases; china; coronavirus; cov-2; covid-19; disease; human; infection; mers; novel; outbreak; patients; sars; study; syndrome; treatment
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        item: #4084 of 7819
          id: cord-305479-o47mv4uw
      author: Feng, Xiaobo
       title: Clinical Characteristics and Short-Term Outcomes of Severe Patients With COVID-19 in Wuhan, China
        date: 2020-08-06
       words: 3639
      flesch: 45
     summary: In addition, univariate and multivariate Cox analyses of potential factors for poor outcome patients indicated that cytokine storms and uncontrolled inflammation responses as well as liver, kidney, and cardiac dysfunction are related to the development of a poor outcome. Previous studies have shown that 20% of COVID-19 patients developed critical disease due to hypoxia or respiratory failure.
    keywords: characteristics; clinical; coronavirus; covid-19; group; outcome; patients; study
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        item: #4085 of 7819
          id: cord-305497-rlxrn3ap
      author: Chorin, Ehud
       title: QT Interval Prolongation and Torsade De Pointes in Patients with COVID-19 treated with Hydroxychloroquine/Azithromycin
        date: 2020-05-12
       words: 1625
      flesch: 40
     summary: Tables: Table 1 Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Chloroquine and hydroxychloroquine in covid-19 Chronic hydroxychloroquine use associated with QT prolongation and refractory ventricular arrhythmia Suspected hydroxychloroquine-associated QTinterval prolongation in a patient with systemic lupus erythematosus Azithromycin-induced torsade de pointes Azithromycin as a cause of QT-interval prolongation and torsade de pointes in the absence of other known precipitating factors The QT interval in patients with COVID-19 treated with hydroxychloroquine and azithromycin The measurement of the QT interval Risk factors for aborted cardiac arrest and sudden cardiac death in children with the congenital long-QT syndrome Risk of aborted cardiac arrest or sudden cardiac death during adolescence in the long-QT syndrome Journal of the American College of Cardiology Prevention of Torsade de Pointes in Hospital Settings A Scientific Statement From the American Heart Association and the American College of Cardiology Foundation Urgent Guidance for Navigating and Circumventing the QTc-Prolonging and Torsadogenic Potential of Possible Pharmacotherapies for Coronavirus Disease 19 (COVID-19) Meta-analysis of the risk of torsades de pointes in patients treated with intravenous racemic sotalol An algorithm for continuous real-time QT interval monitoring Azithromycin plus chloroquine: combination therapy for protection against malaria and sexually transmitted infections in pregnancy Azithromycin, cardiovascular risks, QTc interval prolongation, torsade de pointes, and regulatory issues: A narrative review based on the study of case reports Genetic Susceptibility for COVID-19-Associated Sudden Cardiac Death in African Americans Risk factors and predictors of Torsade de Pointes ventricular tachycardia in patients with left ventricular Systolic dysfunction receiving Dofetilide Torsades de pointes induced by antibiotics Torsade de Pointes due to noncardiac drugs -Most patients have easily identifiable risk factors Safety of hydroxychloroquine, alone and in combination with azithromycin, in light of rapid wide-spread use for COVID-19: a multinational, network cohort and self-controlled case series study Chloroquine diphosphate in two different dosages as adjunctive therapy of hospitalized patients with severe respiratory syndrome in the context of coronavirus (SARS-CoV-2) infection: Preliminary safety results of a randomized, double-blinded Chloroquine-induced torsade de pointes in a COVID-19 patient Azithromycin Causes a Novel Proarrhythmic Syndrome SARS-CoV-2, COVID-19, and inherited arrhythmia syndromes. key: cord-305497-rlxrn3ap authors: Chorin, Ehud; Wadhwani, Lalit; Magnani, Silvia; Dai, Matthew; Shulman, Eric; Nadeau-Routhier, Charles; Knotts, Robert; Bar-Cohen, Roi; Kogan, Edward; Barbhaiya, Chirag; Aizer, Anthony; Holmes, Douglas; Bernstein, Scott; Spinelli, Michael; Park, David S.; Stefano, Carugo; Chinitz, Larry A.; Jankelson, Lior title: QT Interval Prolongation and Torsade De Pointes in Patients with COVID-19 treated with Hydroxychloroquine/Azithromycin date: 2020-05-12 journal:
    keywords: covid-19; patients; prolongation; qtc; risk
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        item: #4086 of 7819
          id: cord-305530-b6r6j1ek
      author: Yang, Po
       title: Feasibility of Controlling COVID-19 Outbreaks in the UK by Rolling Interventions
        date: 2020-04-07
       words: 3424
      flesch: 45
     summary: The effectiveness and impact of suppression and mitigation to control outbreaks of COVID-19 depends on intervention intensity and duration, which remain unclear at the present time. Its implementation hinges on two parameters: intervention intensity presented by average-number contacts per person, and intervention duration counted by weeks.
    keywords: cases; covid-19; intensity; intervention; london
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        item: #4087 of 7819
          id: cord-305534-936peb1n
      author: Johnson, Kemmian D.
       title: Pulmonary and Extra-Pulmonary Clinical Manifestations of COVID-19
        date: 2020-08-13
       words: 6730
      flesch: 34
     summary: The main reason for the development of these symptoms is the presence of severe pneumonia in COVID-19 patients. However, the pulmonary symptoms can vary in COVID-19 patients, possibly due to variation in severity of disease at the time of presentation.
    keywords: acute; coronavirus; cov-2; covid-19; disease; injury; manifestations; patients; sars; study; syndrome
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        item: #4088 of 7819
          id: cord-305539-vynlbty5
      author: Park, Byunggeon
       title: Prognostic Implication of Volumetric Quantitative CT Analysis in Patients with COVID-19: A Multicenter Study in Daegu, Korea
        date: 2020-08-04
       words: 2875
      flesch: 41
     summary: When the clinical severity was subdivided into mild and severe cases, the clinically severe group of COVID-19 patients showed more frequent bilateral distribution (2) and a wider extent of COVID-19 pneumonia than the clinically mild cases (7) . In conclusion, CRP level was an independent predictor of ICU admission, ventilator care, or death in the mild pneumonia group, whereas the proportion of normally aerated lung parenchyma and normally aerated lung volume from volumetric quantitative CT image analysis were independent predictors of CEFS in the severe pneumonia group.
    keywords: analysis; covid-19; group; patients; pneumonia
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        item: #4089 of 7819
          id: cord-305542-zyxqcfa3
      author: Oliver, Nuria
       title: Mobile phone data for informing public health actions across the COVID-19 pandemic life cycle
        date: 2020-06-05
       words: 4490
      flesch: 36
     summary: key: cord-305542-zyxqcfa3 authors: Oliver, Nuria; Lepri, Bruno; Sterly, Harald; Lambiotte, Renaud; Deletaille, Sébastien; De Nadai, Marco; Letouzé, Emmanuel; Salah, Albert Ali; Benjamins, Richard; Cattuto, Ciro; Colizza, Vittoria; de Cordes, Nicolas; Fraiberger, Samuel P.; Koebe, Till; Lehmann, Sune; Murillo, Juan; Pentland, Alex; Pham, Phuong N; Pivetta, Frédéric; Saramäki, Jari; Scarpino, Samuel V.; Tizzoni, Michele; Verhulst, Stefaan; Vinck, Patrick title: Mobile phone data for informing public health actions across the COVID-19 pandemic life cycle date: 2020-06-05 journal: Sci Adv DOI: 10.1126/sciadv.abc0764 sha: doc_id: 305542 cord_uid: zyxqcfa3 nan global scale and spread of the COVID-19 pandemic highlight the need for a more harmonized or coordinated approach. In the following sections, we outline the ways in which different types of mobile phone data can help to better target and design measures to contain and slow the spread of the COVID-19 pandemic.
    keywords: covid-19; data; governments; information; measures; mobile; mobility; network; pandemic; phone; time; use
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        item: #4090 of 7819
          id: cord-305568-8seufdv0
      author: Rohani, Pejman
       title: Protein losing enteropathy and pneumatosis intestinalis in a child with COVID 19 infection
        date: 2021-01-31
       words: 2230
      flesch: 44
     summary: After management of infection children discharged without surgical intervention [10] .There are several case reports about acute appendicitis like presentation and acute surgical abdomen in adults [11] [12] We conclude that COVID 19 infection may present with severe acute abdominal pain and mimic acute appendicitis.
    keywords: children; covid; infection; pain; patient
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        item: #4091 of 7819
          id: cord-305574-ldkri5gh
      author: Mesnier, Jules
       title: Hospital admissions for acute myocardial infarction before and after lockdown according to regional prevalence of COVID-19 and patient profile in France: a registry study
        date: 2020-09-18
       words: 4432
      flesch: 40
     summary: Hospital admissions for acute myocardial infarction before and after lockdown according to regional prevalence of COVID-19 and patient profile in France: a registry study date: 2020-09-18 journal: Lancet Public Health DOI: 10.1016/s2468-2667(20)30188-2 sha: doc_id: 305574 cord_uid: ldkri5gh BACKGROUND: We aimed to evaluate the effect of a nationwide lockdown in France on admissions to hospital for acute myocardial infarction, by patient characteristics and regional prevalence of the pandemic.
    keywords: admissions; covid-19; decrease; hospital; infarction; lockdown; patients; stemi; weeks
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        item: #4092 of 7819
          id: cord-305582-3hmsknon
      author: Li, Lei
       title: Therapeutic strategies for critically ill patients with COVID-19
        date: 2020-04-20
       words: 6194
      flesch: 35
     summary: Available drug options that come from the clinical experience of treating SARS, MERS and other previous influenza virus have been used for the treatment of COVID-19 patients. Considering the high incidence of bacterial infection for critically ill patients with COVID-19, it is essential to test the kinetics of procalcitonin (PCT) and C-reaction protein (CRP) in COVID-19 patients for timely diagnosis and intervention of bacterial infection.
    keywords: 2019; acute; antiviral; coronavirus; covid-19; infection; influenza; ncov; patients; sars; syndrome; therapy; treatment; ventilation
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        item: #4093 of 7819
          id: cord-305618-tq401g18
      author: Kim, Beom Joon
       title: Management of Acute Stroke Patients Amid the Coronavirus Disease 2019 Pandemic: Scientific Statement of the Korean Stroke Society
        date: 2020-05-12
       words: 1455
      flesch: 40
     summary: Their plans can be summarized as follows: (1) centralization of regional stroke systems of care and (2) development and implementation of protected intramural code stroke protocols to ensure the quality of stroke care and protect hospital personnel from the SARS-CoV-2 infection. Challenges and potential solutions of stroke care during the coronavirus disease 2019 (covid-19) outbreak Infection prevention and control during health care when covid-19 is suspected Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Clinical course and outcomes of patients with severe acute respiratory syndrome coronavirus 2 infection: a preliminary report of the first 28 patients from the Korean cohort study on COVID-19 Acute cerebrovascular disease following covid-19: a single center, retrospective, observational study Neurological manifestations of hospitalized patients with covid-19 in Wuhan, China: a retrospective case series study Temporary emergency guidance to US stroke centers during the COVID-19 pandemic Menon BK.
    keywords: acute; covid-19; patients; stroke
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        item: #4094 of 7819
          id: cord-305629-utjng3dq
      author: Kutralam-Muniasamy, Gurusamy
       title: Impacts of the COVID-19 lockdown on air quality and its association with human mortality trends in megapolis Mexico City
        date: 2020-10-28
       words: 4786
      flesch: 41
     summary: The present study assessed air quality and its association with human mortality rates during the lockdown by estimating changes observed in air pollutants (CO, NO(2), O(3), SO(2), PM(10) and PM(2.5)) between the lockdown (April 1–May 31) and prelockdown (January 1–March 31) periods, as well as by comparing the air quality data of lockdown period with the same interval of previous 5 years (2015–2019). Thus, the main objective of this paper is (1) to assess the impact of COVID-19 measures on air quality by evaluating the levels of air pollutants, i.e. CO, NO 2 , O 3 , SO 2 , PM 10 and PM 2.5 , between January 1 and May 31, 2020, and comparing the air quality of the lockdown interval with the same period of previous 5 years, (2) to evaluate their associations with mobility trends and (3) to empirically analyse whether or not the concentration level of air pollutants can contribute to the outbreak of COVID-19.
    keywords: air; april; city; covid-19; lockdown; mexico; period; pollutants; quality
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        item: #4095 of 7819
          id: cord-305632-xbji6g5x
      author: Uccelli, Matteo
       title: COVID-19 and Obesity: Is Bariatric Surgery Protective? Retrospective Analysis on 2145 Patients Undergone Bariatric-Metabolic Surgery from High Volume Center in Italy (Lombardy)
        date: 2020-10-31
       words: 2897
      flesch: 44
     summary: A total of 231 (10.8%) patients were prescribed home isolation following the development of symptoms or contact with COVID-19 patients (fiduciary home quarantine). [19] [20] ; to avoid possible compilation errors by patients, we preferred to omit the symptoms related to loss of taste and smell, as bariatric patients often present these symptoms immediately and long after bariatric surgery
    keywords: covid-19; disease; italy; obesity; patients; sars; surgery
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        item: #4096 of 7819
          id: cord-305657-ayqxesiv
      author: Kalra, Mannudeep K.
       title: Chest CT practice and protocols for COVID-19 from radiation dose management perspective
        date: 2020-07-03
       words: 3965
      flesch: 45
     summary: CEBM Laboratory Diagnosis of COVID-19: Current Issues and Challenges Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Fast, portable tests come online to curb coronavirus pandemic Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection The Clinical and Chest CT Features Associated With Severe and Critical COVID-19 Pneumonia Chest CT severity score: an imaging tool for assessing severe COVID-19 CT image visual quantitative evaluation and clinical classification of coronavirus disease (COVID-19) Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT Chest CT for typical 2019-nCoV pneumonia: relationship to negative RT-PCR testing Coronavirus disease 2019: initial detection on chest CT in a retrospective multicenter study of 103 Chinese subjects Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Sensitivity of chest CT for COVID-19: comparison to RT-PCR Chest CT and RT-PCR: radiologists' experience in the diagnosis of COVID-19 in China Frequency and distribution of chest radiographic findings in COVID-19 positive patients Can lung US help critical care clinicians in the early diagnosis of novel coronavirus (COVID-19) pneumonia? Yet, chest CT is often used in patients with known or suspected COVID-19 due to regional preferences, lack of availability of PCR assays, and false-negative PCR assays, as well as for monitoring of disease progression, complications, and treatment response.
    keywords: chest; covid-19; dose; patients; pcr; pneumonia; use
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        item: #4097 of 7819
          id: cord-305659-4pdtqmgp
      author: Kemmner, Stephan
       title: Cyclosporine as preferred calcineurin inhibitor in renal allograft recipients with COVID-19 infection
        date: 2020-06-04
       words: 157
      flesch: 18
     summary: Therefore, switching to a Cyclosporine-based immunosuppression may represent another therapeutic option in the case of COVID-19 infection following kidney transplantation. A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia COVID-19 infection in kidney transplant recipients Early experience with COVID-19 in kidney transplantation Cyclosporin
    keywords: kidney
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        item: #4098 of 7819
          id: cord-305682-b232ra0j
      author: Rahaman Khan, Md Hasinur
       title: COVID-19 Outbreak Situations in Bangladesh: An Empirical Analysis
        date: 2020-04-22
       words: 3786
      flesch: 59
     summary: As of today, we have found very few research works on COVID-19 that have been conducted using Bangladesh data. https://doi.org/10.1101 measure the risk of infectious disease and predict the risk of COVID-19 transmission using Bangladesh data along with other four countries-United States, Australia, Canada and China.
    keywords: april; bangladesh; covid-19; deaths; license; number; preprint
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        item: #4099 of 7819
          id: cord-305703-ypeibwje
      author: Veronese, Nicola
       title: Use of Corticosteroids in Coronavirus Disease 2019 Pneumonia: A Systematic Review of the Literature
        date: 2020-04-24
       words: 2884
      flesch: 30
     summary: Therefore, the clinical, therapeutic, and side effects of systemic glucocorticoid therapy in COVID-19 patients are currently unclear. When considering patients with SARS and MERS, the use of corticosteroids therapy is still debated (20, 21) .
    keywords: ards; corticosteroids; covid-19; patients; review; studies; use
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        item: #4100 of 7819
          id: cord-305739-hr52e5iz
      author: Kiddell-Monroe, Rachel
       title: Inuit communities can beat COVID-19 and tuberculosis
        date: 2020-04-25
       words: 406
      flesch: 43
     summary: key: cord-305739-hr52e5iz authors: Kiddell-Monroe, Rachel; Ranta, Malcolm; Enook, Sheila; Saranchuk, Peter title: Inuit communities can beat COVID-19 and tuberculosis date: 2020-04-25 journal: Lancet Public Health DOI: 10.1016/s2468-2667(20)30091-8 sha: doc_id: 305739 cord_uid: hr52e5iz nan Inuit communities are at high risk for respiratory infections and coronavirus disease 2019 (COVID-19) because they are currently fighting another respiratory infection epidemic, tuberculosis. 1 COVID-19 has been reported in Inuit communities in Nunavik, Canada; however, no case of COVID-19 disease has been reported in Nunavut, Canada.
    keywords: covid-19; tuberculosis
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        item: #4101 of 7819
          id: cord-305760-43qxf408
      author: Elgendi, M.
       title: The Evaluation of Deep Neural Networks and X-Ray as a Practical Alternative for Diagnosis and Management of COVID-19
        date: 2020-05-16
       words: 2470
      flesch: 48
     summary: A comparison of optimal neural networks recommended in previous studies, along with the optimal neural network suggested by this work, is shown in Table 2 . Sethy and Behera 8 explored 10 different pretrained neural networks, reporting an accuracy of 93% on a balanced dataset, for detecting COVID-19 on X-ray images.
    keywords: accuracy; covid-19; images; networks; ray
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        item: #4102 of 7819
          id: cord-305763-160heazx
      author: Lai, Chih-Cheng
       title: Population-based seroprevalence surveys of anti-SARS-CoV-2 antibody: An up-to-date review
        date: 2020-10-09
       words: 4262
      flesch: 38
     summary: In Denmark, a total of 20,640 blood donations were given by 17-69-year-old donors from April 6 to May 3, 2020, which were then subjected to a plasma or whole blood lateral flow test according to the manufacturer's recommendations (IgM/IgG Antibody to SARS-CoV-2 lateral flow test; Livzon Diagnostics Inc., Zhuhai, Guangdong, China) (Erikstrup et al et al., 2020) . The overall unadjusted seroprevalence was 2.0% (95% CI, 1.8-2.2), and after adjusting for assay sensitivity and specificity (including their CI), the overall seroprevalence was 1.9% (95% CI, 0.8-2.3) (Erikstrup et al et al., 2020) .
    keywords: antibodies; cov-2; covid-19; et al; igg; sars; seroprevalence; study
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        item: #4103 of 7819
          id: cord-305770-xygg4lxu
      author: Busetto, Gian Maria
       title: SARS-CoV-2 Infection and High-Risk Non-Muscle-Invasive Bladder Cancer: Are There Any Common Features?
        date: 2020-06-09
       words: 6974
      flesch: 36
     summary: COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis Coronavirus infections and immune responses Dysregulation of immune response in patients with COVID-19 in Wuhan, China Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China EAU Guidelines on Non-Muscle-invasive Urothelial Carcinoma of the Bladder: Update Circulating Tumor Cells Identify Patients with Super-High-Risk Non-Muscle-Invasive Bladder Cancer: Updated Outcome Analysis of a Prospective Single-Center Trial Prognostic role of pretreatment neutrophil-to-lymphocyte ratio (NLR) in patients with non-muscle-invasive bladder cancer (NMIBC): A systematic review and metaanalysis Cancer-related inflammation and treatment effectiveness Evaluation of the prognostic value of LMR, PLR, NLR, and dNLR in urothelial bladder cancer patients treated with radical cystectomy The clinical use of neutrophil-to-lymphocyte ratio in bladder cancer patients: a systematic review and meta-analysis Type 2 diabetes mellitus predicts worse outcomes in patients with high-grade T1 bladder cancer receiving bacillus Calmette-Guérin after transurethral resection of the bladder tumor Aging, inflammation and cancer Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy Urothelial tumors of the bladder Aging and the immune system: an overview The Biology of Aging and Cancer: Frailty, Inflammation, and Immunity Cellular senescence: when bad things happen to good cells Reversal of human cellular senescence: roles of the p53 and p16 pathways Aging, cellular senescence, and cancer Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion Epithelial-mesenchymal transition induced by senescent fibroblasts. Furthermore, the risk of severe events has been reported as higher for cancer patients and even higher for patients undergoing treatments like chemotherapy [65] .
    keywords: analysis; bladder; cancer; covid-19; disease; il-6; inflammation; patients; progression; response; risk; sars; system; tumor
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        item: #4104 of 7819
          id: cord-305782-gnzwe2z2
      author: Satici, Celal
       title: Performance of Pneumonia Severity Index and CURB-65 in Predicting 30-day mortality in patients with COVID-19
        date: 2020-06-14
       words: 3390
      flesch: 49
     summary: A prospective cohort study Correlation between the variables collected at admission and progression to severe cases during hospitalization among COVID-19 patients in Chongqing 30-day mortality in patients hospitalized with COVID-19 during the first wave of the Italian epidemic: a prospective cohort study Characteristics and circumstances of falls in a hospital setting: A prospective analysis Clinical features of patients infected with 2019 novel coronavirus in Wuhan Albumin and C-reactive protein have prognostic significance in patients with community-acquired pneumonia Clinical features of COVID-19 in elderly patients: A comparison with young and middle-aged patients Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province Neutrophil-to-lymphocyte ratio as an independent risk factor for mortality in hospitalized patients with COVID-19 CURB 65 score as a predictor of early mortality in hospital-acquired pneumonia Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan Validity of pneumonia severity index and CURB-65 severity scoring systems in community acquired pneumonia in an Indian setting C-reactive protein levels in the early stage of COVID-19 WHO Novel Coronavirus (2019-nCoV) situation report Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Prediction models for diagnosis and prognosis of covid-19 infection: Systematic review and critical appraisal An interpretable mortality prediction model for COVID-19 patients Analysis of 92 deceased patients with COVID-19 D-dimer levels on admission to predict inhospital mortality in patients with Covid-19 Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Essential psychological problems of hospitalized patients II or III versus IV or V. Abbreviations: CI: confidence interval, PPV: positive predictive values, NPV: negative predictive values, AUC: area under curve In conclusion, this single center retrospective study including a large cohort of COVID-19 patients showed that PSI is a powerful tool to predict mortality in patients with COVID-19.
    keywords: covid-19; curb-65; day; mortality; patients; psi
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        item: #4105 of 7819
          id: cord-305793-xmkiqgbn
      author: Giovannoni, Gavin
       title: Anti-CD20 immunosuppressive disease-modifying therapies and COVID-19
        date: 2020-04-18
       words: 939
      flesch: 35
     summary: This may explain why patients on anti-CD20 therapies cope relatively well with viral infections. The existing and emerging data indicate that anti-CD20 therapies are likely to be safe to initiate and redose during the COVID-19 pandemic.
    keywords: covid-19; patients
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        item: #4106 of 7819
          id: cord-305828-kueqo67y
      author: Ma, Yarong
       title: Psychological Stress among Health Care Professionals during the 2019 Novel Coronavirus Disease Outbreak: Cases from Online Consulting Customers
        date: 2020-06-28
       words: 2154
      flesch: 39
     summary: key: cord-305828-kueqo67y authors: Ma, Yarong; Rosenheck, Robert; He, Hongbo title: Psychological Stress among Health Care Professionals during the 2019 Novel Coronavirus Disease Outbreak: Cases from Online Consulting Customers date: 2020-06-28 journal: Intensive Crit Care Nurs DOI: 10.1016/j.iccn.2020.102905 sha: doc_id: 305828 cord_uid: kueqo67y BACKGROUND: During the 2019 novel coronavirus disease (COVID-19) outbreak, online consulting has been widely used to address mental health problems, including health care professionals (HCPs) caring for COVID-19 patients who experienced substantial psychological distress. A cross-sectional online survey was conducted among health care professionals who sought online psychological support provided by the staff of the Affiliated Brain Hospital of Guangzhou Medical University (a large psychiatric hospital in southern China).
    keywords: care; covid-19; health; online; stress
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        item: #4107 of 7819
          id: cord-305856-xt3zxajf
      author: Shanmugam, Chandrakumar
       title: COVID-2019 – A comprehensive pathology insight
        date: 2020-09-18
       words: 4607
      flesch: 32
     summary: The earliest case of SARS CoV-2 infection currently known was reported on 31st December 2019 in Wuhan, Hubei province of China. Furthermore, SARS CoV-2 infection in pregnant women raised a possibility of vertical transmission.
    keywords: cases; china; coronavirus; covid-19; disease; infection; novel; pathology; patients; pneumonia; sars; syndrome; transmission
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        item: #4108 of 7819
          id: cord-305858-gp1u4kh7
      author: Song, Xiang
       title: High expression of angiotensin-converting enzyme-2 (ACE2) on tissue macrophages that may be targeted by virus SARS-CoV-2 in COVID-19 patients
        date: 2020-07-19
       words: 4909
      flesch: 42
     summary: The data suggests that SARS-CoV-2 virus may not directly attack blood immune cells lacking the ACE2 expression. To better understand the pathogenesis of COVID-19 and build up the host anti-viral immunity, we examined the levels of ACE2 expression on different types of immune cells including tissue macrophages.
    keywords: ace2; blood; cells; cov-2; covid-19; expression; figure; human; macrophages; sars; tissue; usa
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        item: #4109 of 7819
          id: cord-305929-kxiuhu5m
      author: rugarabamu, s.
       title: Knowledge, attitudes, and practices (KAP) towards COVID-19: A quick online cross-sectional survey among Tanzanian residents.
        date: 2020-05-01
       words: 2390
      flesch: 51
     summary: Previous studies from different part of the world have identified good knowledge in infection control as a predictor of good practice [17, 18] , in addition other studies have highlighted that major gaps in COVID-19 knowledge could result in uncertainties and non-stringent control measures [19] . Suggesting that health education programs aimed at improving COVID-19 knowledge are helpful for encouraging an optimistic attitudes and maintaining safe practices.
    keywords: covid-19; knowledge; preprint; residents; tanzania
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        item: #4110 of 7819
          id: cord-305941-277iqp0u
      author: Bozdağ, Faruk
       title: Psychological Resilience of Healthcare Professionals During COVID-19 Pandemic
        date: 2020-10-13
       words: 5266
      flesch: 35
     summary: Therefore, this study aims to probe psychological resilience of healthcare workers. Doctors constitute the group with the lowest levels of psychological resilience among healthcare workers.
    keywords: covid-19; healthcare; pandemic; professionals; psychological; resilience; study; workers
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        item: #4111 of 7819
          id: cord-305956-l02xdq87
      author: Alqahtani, Saleh A
       title: Liver injury in COVID-19: The current evidence
        date: 2020-05-26
       words: 3066
      flesch: 36
     summary: A retrospective study Liver impairment in COVID-19 patients: A retrospective analysis of 115 cases from a single center in Wuhan city, China. Cautious use of antiviral agents in patients with decompensated liver disease and drug-drug interactions in post liver transplant patients has to be considered.
    keywords: cov-2; covid-19; disease; infection; injury; liver; patients; sars
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        item: #4112 of 7819
          id: cord-305959-x061q8t7
      author: Davoudi-Monfared, Effat
       title: A Randomized Clinical Trial of the Efficacy and Safety of Interferon β-1a in Treatment of Severe COVID-19
        date: 2020-08-20
       words: 4746
      flesch: 46
     summary: In this randomized clinical trial, the efficacy and safety of IFN ␤-1a were evaluated in patients with severe COVID-19. The present study was the first randomized, open-label, controlled trial that assessed the efficacy and safety of IFN ␤-1a in the treatment of patients diagnosed with severe COVID-19.
    keywords: clinical; control; covid-19; group; ifn; interferon; mortality; patients; study; treatment
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        item: #4113 of 7819
          id: cord-305965-yzx21hp7
      author: Ramalingam, HariPrasad
       title: Delayed Diagnosis of Postintubation Tracheal Stenosis due to the Coronavirus Disease 2019 Pandemic: A Case Report
        date: 2020-06-23
       words: 1348
      flesch: 51
     summary: She was kept in the isolation ward for 1 day with severe dyspnea due to tracheal stenosis. Other factors that contribute to tracheal stenosis are cuff pressure, ETT size relative to the tracheal lumen, duration of intubation, hemodynamics during intubation, movement of the tube, age, sex, ETT material, and the use of steroids.
    keywords: covid-19; patient; stenosis; tracheal
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        item: #4114 of 7819
          id: cord-305969-yy4f4x5i
      author: Eng, John
       title: Imaging Publications in the COVID-19 Pandemic: Applying New Research Results to Clinical Practice
        date: 2020-04-23
       words: 1833
      flesch: 43
     summary: Marked differences are likely to exist between your practice versus research study populations. Most articles examining CT's diagnostic performance focus on its sensitivity for diagnosing COVID-19 pneumonia against the reference standard, reverse transcriptase polymerase chain reaction (RT-PCR) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (2).
    keywords: covid-19; sensitivity; specificity
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        item: #4115 of 7819
          id: cord-306008-kh4y44uy
      author: Khalatbari-Soltani, Saman
       title: Importance of collecting data on socioeconomic determinants from the early stage of the COVID-19 outbreak onwards
        date: 2020-05-07
       words: 3196
      flesch: 38
     summary: We included studies that were written in English and reported descriptive characteristics of COVID-19 cases or reported risk factors of COVID-19 incidence, severity and mortality. As observed across the world, once COVID-19 cases appear initially from abroad, the community spread of disease will depend upon the specific local infrastructures and social inequalities in each context.
    keywords: covid-19; data; disease; factors; health; measures; risk; sep
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        item: #4116 of 7819
          id: cord-306016-2gudro8v
      author: Pelt, Christopher E.
       title: The Rapid Response to the COVID-19 Pandemic by the Arthroplasty Divisions at Two Academic Referral Centers
        date: 2020-04-21
       words: 3754
      flesch: 39
     summary: Finally, this 129 approach failed to account for the urgent/complex cases that may have warranted surgery more 130 expediently than other patients due to the potential for ongoing and/or irreversible damage with 131 prolonged delay. In order to ensure and provide for adequate health care resources in terms of hospital capacity, personnel and personal protective equipment (PPE), service lines such as adult reconstruction and lower limb arthroplasty have stopped or substantially limited elective surgeries and have been forced to re-engineer care processes for a high-volume of patients.
    keywords: arthroplasty; care; covid-19; elective; health; pandemic; patients; surgery
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        item: #4117 of 7819
          id: cord-306034-1u29o2id
      author: Cazzolla, Angela P.
       title: Taste and Smell Disorders in COVID-19 Patients: Role of Interleukin-6
        date: 2020-08-04
       words: 4019
      flesch: 36
     summary: In addition, recent studies have shown that taste cells produce, in response to inflammatory stimuli, high levels of various molecules associated with internal defense responses, including multiple inflammatory cytokines. In the present study, chemosensitive dysfunctions are more frequent in males (67.2%) and the prevalence of olfactory dysfunction is higher than that of taste dysfunction (65.7% vs 25.4%).
    keywords: cells; covid-19; delta; disorders; il-6; levels; olfactory; patients; smell; taste
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        item: #4118 of 7819
          id: cord-306070-2dgs5oih
      author: Askin, Ozge
       title: Cutaneous manifestations in hospitalized patients diagnosed as COVID‐19
        date: 2020-06-24
       words: 2117
      flesch: 50
     summary: The most commonly observed skin eruption in COVID-19 patients was erythematous scaly rash in our study. key: cord-306070-2dgs5oih authors: Askin, Ozge; Altunkalem, Rozerin Neval; Altinisik, Dursun Dorukhan; Uzuncakmak, Tugba Kevser; Tursen, Umit; Kutlubay, Zekayi title: Cutaneous manifestations in hospitalized patients diagnosed as COVID‐19 date: 2020-06-24 journal: Dermatol Ther DOI: 10.1111/dth.13896 sha: doc_id: 306070 cord_uid: 2dgs5oih BACKGROUND: Cutaneous manifestations of COVID‐19 disease have not yet been fully described.
    keywords: covid-19; findings; manifestations; patients; study
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        item: #4119 of 7819
          id: cord-306072-tfvt6sjq
      author: Ong, Sean Wei Xiang
       title: Safety and potential efficacy of cyclooxygenase‐2 inhibitors in coronavirus disease 2019
        date: 2020-07-26
       words: 3120
      flesch: 37
     summary: In this population at increased risk of severe COVID-19 (≥ 50 years old and with radiographic pneumonia), there was no evidence that COX-2 inhibitor treatment was associated with an increase in adverse outcomes, supporting the use of short duration therapy in COVID-19 for symptom relief and as an anti-pyretic. The detailed clinical course of all patients in the treatment group, including timing and duration of COX-2 inhibitor treatment, is illustrated in Figure 1 .
    keywords: covid-19; disease; group; il-6; inhibitors; patients; study; treatment
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        item: #4120 of 7819
          id: cord-306108-ja0wyr5w
      author: B K, Anupama
       title: A Review of Acute Myocardial Injury in Coronavirus Disease 2019
        date: 2020-06-03
       words: 4760
      flesch: 28
     summary: In general, as the presence of CVD and myocardial injury in COVID-19 patients has been associated with more severe outcomes and increased mortality, triaging patients with COVID-19 according to the presence of underlying CVD and evidence of myocardial injury for prioritized treatment strategies may be reasonable [25] . Among various cardiac complications, acute cardiac injury with elevated cardiac biomarkers has been described in early studies from China on hospitalized patients with COVID-19.
    keywords: acute; cardiac; covid-19; disease; injury; myocarditis; patients; sars; troponin
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        item: #4121 of 7819
          id: cord-306141-19o76jqr
      author: Käpplinger, Bernd
       title: “The lockdown of physical co-operation touches the heart of adult education”: A Delphi study on immediate and expected effects of COVID-19
        date: 2020-11-06
       words: 6832
      flesch: 58
     summary: key: cord-306141-19o76jqr authors: Käpplinger, Bernd; Lichte, Nina title: “The lockdown of physical co-operation touches the heart of adult education”: A Delphi study on immediate and expected effects of COVID-19 date: 2020-11-06 journal: Int Rev Educ DOI: 10.1007/s11159-020-09871-w sha: doc_id: 306141 cord_uid: 19o76jqr This article is based on the first wave of an ongoing worldwide Delphi study which is currently analysing the immediate and expected effects of the COVID-19 pandemic on adult education and adult learning.
    keywords: adult; adult education; covid-19; crisis; delphi; education; experts; future; learning; social; study
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        item: #4122 of 7819
          id: cord-306149-sd0s0jup
      author: Ratanarat, Ranistha
       title: Critical Care Management of Patients with COVID-19: Early Experience in Thailand
        date: 2020-05-18
       words: 3098
      flesch: 40
     summary: The objective of this report is to outline our initial experience with the management of COVID-19 patients requiring intensive care unit (ICU) admission. Chest computed tomography (CT) findings in COVID-19 patients are more specific, showing bilateral, multi-lobar ground-glass opacification with the so-called crazy paving.
    keywords: care; cases; coronavirus; covid-19; disease; patients; thailand; therapy
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        item: #4123 of 7819
          id: cord-306177-5wefp31y
      author: Iheagwam, Franklyn Nonso
       title: Computer-Aided Analysis of Multiple SARS-CoV-2 Therapeutic Targets: Identification of Potent Molecules from African Medicinal Plants
        date: 2020-09-12
       words: 4840
      flesch: 37
     summary: (Supplementary Materials) COVID-19 infection: origin, transmission, and characteristics of human coronaviruses e epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak COVID-19 outbreak: migration, effects on society, global environment and prevention COVID-19: from bench to bed side Novel coronavirus: from discovery to clinical diagnostics World Health Organisation, Naming the Coronavirus Disease (COVID-19) and the Virus that Causes it 2020, World Health Organisation Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China World Health Organisation, Coronavirus Disease (COVID-19) Situation Report-140, World Health Organisation Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): the epidemic and the challenges Learning from the past: possible urgent prevention and treatment options for severe acute respiratory infections caused by 2019-nCoV Drug treatment options for the 2019-new coronavirus (2019-nCoV) Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro COVID-19 pandemic: a pragmatic plan for ayurveda intervention Traditional Chinese medicine for COVID-19 treatment In silico tools to study molecular targets of neglected diseases: inhibition of TcSir2rp3, an epigenetic enzyme of Trypanosoma cruzi Computational screening for potential drug candidates against the SARS-CoV-2 main protease Drug repurposing for coronavirus (COVID-19): in silico screening of known drugs against coronavirus 3CL hydrolase and protease enzymes Potential inhibitors for novel coronavirus protease identified by virtual screening of 606 million compounds Rapid identification of potential inhibitors of SARS-CoV-2 main protease by deep docking of 1.3 billion compounds Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods Matrix metallopeptidase 9 as a host protein target of chloroquine and melatonin for immunoregulation in COVID-19: a network-based meta-analysis Large-scale ligand-based virtual screening for SARS-CoV-2 inhibitors using deep neural networks Identification of novel compounds against three targets of SARS CoV-2 coronavirus by combined virtual screening and supervised machine learning Artificial intelligence approach fighting COVID-19 with repurposing drugs Consensus virtual screening of dark chemical matter and Food chemicals uncover potential inhibitors of SARS-CoV-2 main protease Virtual screening and repurposing of FDA approved drugs against COVID-19 main protease Fast identification of possible drug treatment of coronavirus disease-19 (COVID-19) through computational drug repurposing study Marine natural compounds as potents inhibitors against the main protease of SARS-CoV-2 a molecular dynamic study Databases for facilitating mechanistic investigations of traditional Chinese medicines against COVID-19 Evaluation of traditional ayurvedic preparation for prevention and management of the novel coronavirus (SARS-CoV-2) using molecular docking approach Identification of new anti-nCoV drug chemical compounds from Indian spices exploiting SARS-CoV-2 main protease as target Open babel: an open chemical toolbox LigParGen web server: an automatic OPLS-AA parameter generator for organic ligands A semiempirical free energy force field with charge-based desolvation Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function Model optimization and in silico analysis of potential dipeptidyl peptidase iv antagonists from GC-MS identified compounds in Nauclea latifolia leaf extracts SWISS-MODEL: homology modelling of protein structures and complexes Verification of protein structures: patterns of nonbonded atomic interactions Assessment of protein models with three-dimensional profiles 3D refine: an interactive web server for efficient protein structure refinement Combining global and local measures for structure-based druggability predictions GEMDOCK: a generic evolutionary method for molecular docking AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules ADMET lab: a platform for systematic ADMET evaluation based on a comprehensively collected ADMET database Advances in homology protein structure modeling QMEANDisCo-distance constraints applied on model quality estimation Computational methods in drug discovery Finding a potential dipeptidyl peptidase-4 (DPP-4) inhibitor for type-2 diabetes treatment based on molecular docking, pharmacophore generation, and molecular dynamics simulation Effects of different brewing conditions on catechin content and sensory acceptance in Turkish green tea infusions Heterogeneity of the interflavanyl bond in proanthocyanidins from natural sources lacking C-4 (C-ring) deoxy flavonoid nucleophiles e flavonoid chemosystematics of Egyptian Verbena species Bioactivity guided fractionation of Phyllanthus orbicularis and identification of the principal anti HSV-2 compounds Procyanidin B1 purified from Cinnamomi cortex suppresses hepatitis C virus replication Identification of polyphenols from Broussonetia papyrifera as SARS CoV-2 main protease inhibitors using in silico docking and molecular dynamics simulation approaches Flavonoidmediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris Procyanidins and butanol extract of Cinnamomi cortex inhibit SARS-CoV infection e role of flavonoids in the antiinflammatory activity of Chamomilla recutita e chemistry and biological activities of natural products from northern African plant families: from Taccaceae to Zygophyllaceae Luteolin-7-O-glucoside present in lettuce extracts inhibits hepatitis B surface antigen production and viral replication by human hepatoma cells in vitro Anti-HBV active flavone glucosides from Euphorbia humifusa willd Computational screening of antagonists against the SARS-CoV-2 (COVID-19) coronavirus by molecular docking In silico computational screening of Kabasura Kudineer-official Siddha formulation and JACOM against SARS-CoV-2 spike protein Amino acid transporters as disease modifiers and drug targets In the course of drug discovery, structure-based virtual screening is a computational approach utilised to identify promising novel small chemical ligands from curated chemical compound databases with potential activity against drug targets [48] .
    keywords: binding; compounds; coronavirus; covid-19; docking; drug; galloylcatechin; helicase; luteolin; potential; protease; sars; targets
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        item: #4124 of 7819
          id: cord-306183-uhnrxuwd
      author: Bousquet, Guilhem
       title: ADL-dependency, D-Dimers, LDH and absence of anticoagulation are independently associated with one-month mortality in older inpatients with Covid-19
        date: 2020-06-23
       words: 2804
      flesch: 51
     summary: All authors Drafting the work: GB, GF, FP Final approval: All authors Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved: All authors Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study COVID-19 and older adults: what we know Covid-19 in critically ill patients in the seattle region -case series Comprehensive geriatric assessment for older hospital patients Diagnostic Testing for Severe Acute Respiratory Syndrome-Related Coronavirus 2: A Narrative Review CT image visual quantitative evaluation and clinical classification of coronavirus disease (COVID-19) Clinical characteristics and outcomes of older patients with coronavirus disease 2019 (COVID-19) in Wuhan, China (2019): a single-centered, retrospective study Frailty as a predictor of disabilities among community-dwelling older people: a systematic review and meta-analysis Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. Since the end of 2019, the SARS-Cov-2 pandemic (named exposes older patients to the risk of early death
    keywords: covid-19; dimers; month; mortality; patients; risk; score
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        item: #4125 of 7819
          id: cord-306195-r2rt3upd
      author: Püschel, Klaus
       title: Corona deaths in Hamburg, Germany
        date: 2020-06-04
       words: 1410
      flesch: 47
     summary: [6] and ultimately contributes to the course of COVID-19 disease and the aggravation of pre-existing comorbidities. With special regard to the kidneys, these findings should raise awareness of the clinical management of SARS CoV-2 patients, including routine urine tests, monitoring and treatment of possible protein loss, loss of AT3, thrombophilia and fluid imbalances.
    keywords: autopsies; cases; covid-19; hamburg; infection
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        item: #4126 of 7819
          id: cord-306199-3ssri5nf
      author: Tseng, Jennifer
       title: How Has COVID-19 Affected the Costs of the Surgical Fellowship Interview Process?
        date: 2020-05-20
       words: 1324
      flesch: 31
     summary: As only two studies provide information about the monetary cost of fellowship interviews, additional reviews were performed of articles focusing on residency interview costs. A literature review of the historical costs of surgical fellowship interviews and a summary of how the shift to virtual interviews has unintended positive and negative effects on costs for applicants and training programs.
    keywords: applicants; fellowship; interviews; residency
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        item: #4127 of 7819
          id: cord-306200-d5qn65k0
      author: Petersen, Eskild
       title: COVID-19 travel restrictions and the International Health Regulations – call for an open debate on easing of travel restrictions
        date: 2020-04-17
       words: 1470
      flesch: 42
     summary: Whilst travel restriction measures that significantly interfere with international traffic may be justified at the beginning of an outbreak, since they allow countries time to implement effective preparedness measures based on careful risk assessment, they should be based on a reasoned scientific evaluation of the available evidence on their possible effectiveness. key: cord-306200-d5qn65k0 authors: Petersen, Eskild; McCloskey, Brian; Hui, David S; Kock, Richard; Ntoumi, Francine; Memish, Ziad A; Kapata, Nathan; Azhar, Esam I; Pollack, Marjorie; Madoff, Larry C.; Hamer, Davidson H; Nachega, Jean B; Pshenichnaya, N.; Zumla, Alimuddin title: COVID-19 travel restrictions and the International Health Regulations – call for an open debate on easing of travel restrictions date: 2020-04-17 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.04.029 sha: doc_id: 306200 cord_uid: d5qn65k0 nan Correspondence:
    keywords: countries; measures; restrictions; travel
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        item: #4128 of 7819
          id: cord-306210-ny3vvu9h
      author: Clarfield, A. Mark
       title: Age, ageing, ageism and “age-itation” in the Age of COVID-19: rights and obligations relating to older persons in Israel as observed through the lens of medical ethics
        date: 2020-11-12
       words: 9583
      flesch: 52
     summary: Without this aid it is difficult for such older persons to cope with social isolation and resulting loneliness. key: cord-306210-ny3vvu9h authors: Clarfield, A. Mark; Jotkowitz, Alan title: Age, ageing, ageism and “age-itation” in the Age of COVID-19: rights and obligations relating to older persons in Israel as observed through the lens of medical ethics date: 2020-11-12 journal:
    keywords: age; ageism; covid-19; disease; example; health; icu; israel; medical; pandemic; people; persons; ref; risk; society
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        item: #4129 of 7819
          id: cord-306214-2wjv6aeb
      author: Medjeral-Thomas, Nicholas R.
       title: Cohort study of outpatient hemodialysis management strategies for COVID-19 in North-West London
        date: 2020-08-25
       words: 2786
      flesch: 42
     summary: Importantly, safe and effective management protocols for COVID-19 haemodialysis patients have not been identified. Fluid balance management of COVID-19 patients has attracted debate 13, 14 .
    keywords: admission; cohort; covid-19; death; dialysis; patients
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        item: #4130 of 7819
          id: cord-306226-znj4gp87
      author: Alemanno, Giovanni
       title: Surgical perspectives and patways in an emergency department during the COVID-19 pandemic
        date: 2020-05-13
       words: 1297
      flesch: 28
     summary: If we consider also the apparent reduction/absence of polytrauma due to social distancing measures imposed by the government, a minor human contact in patient handover (even if digital platforms are provided) and the difficulties in the technical management of surgical COVID-19 patients in emergency settings, this pandemic era is further tempering the spirit of surgeons. This principle of safety for all healthcare professionals obviously translates into implementing all the provisions used in confirmed COVID-19 patients for surgical interventions that are not postponable and that require the immediate availability of the operating room (such as trauma, shock, bleeding, suicide attempts, peritonitis, etc).
    keywords: covid-19; pandemic; surgery; swab
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        item: #4131 of 7819
          id: cord-306227-63qvvkvk
      author: Shammi, Mashura
       title: Strategic assessment of COVID-19 pandemic in Bangladesh: comparative lockdown scenario analysis, public perception, and management for sustainability
        date: 2020-07-18
       words: 9392
      flesch: 46
     summary: (3.5.1-3.5.3) we have analysed emergency management issues including short to medium-term measures as well as long-term management strategies of COVID-19 pandemic lockdown scenarios in Bangladesh based on our research outcomes. PCA showed a significant level of controlling factors in Bangladesh COVID-19 pandemic and how these statements are associated with the various scenarios (Table 7) .
    keywords: analysis; bangladesh; community; country; covid-19; economic; gob; government; health; increase; infection; lockdown; management; movement; pandemic; people; public; scenario; transmission
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        item: #4132 of 7819
          id: cord-306243-ar7xvd2c
      author: Campbell, Katherine H.
       title: Consolidation of Obstetric Services in a Public Health Emergency
        date: 2020-07-22
       words: 3686
      flesch: 33
     summary: Consolidating obstetric services (within a hospital or across a health system) and adapting units to contain COVID-19 (either within an existing labor and delivery unit or building a specialized unit for COVID-19 antepartum, intrapartum, and postpartum patients) should be major considerations for hospital leadership. Strategic planning for the consolidation of obstetric services at a hospital or hospital system level in response to COVID-19 should begin as early as possible.
    keywords: care; covid-19; health; hospital; labor; obstetric; patients; services; unit
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        item: #4133 of 7819
          id: cord-306247-259zacce
      author: Garnica, Marcia
       title: COVID-19 in hematology: data from a hematologic and transplant unit
        date: 2020-09-06
       words: 2646
      flesch: 45
     summary: Regarding HCW, COVID-19 cases started earlier comparing to hematological patients, but most HCW cases occurred after the second week of April, with a cluster distribution of thirteen cases in 2 weeks. After WHO declared COVID-19 a pandemic, a COVID-19 Committee was formed to coordinate all actions and specific areas for COVID-19 patients where delimited, intended not to permit crossover of COVID-19 and other patients.
    keywords: cases; covid-19; hcw; pandemic; patients; transplant
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        item: #4134 of 7819
          id: cord-306270-9bsr2jz0
      author: Chowdhury, Rajiv
       title: Long-term strategies to control COVID-19 in low and middle-income countries: an options overview of community-based, non-pharmacological interventions
        date: 2020-07-13
       words: 3325
      flesch: 40
     summary: As the lockdown is now being relaxed in many LMICs, in this paper, we have (1) conducted an epidemiology-based “options appraisal” of various available non-pharmacological intervention options that can be employed to safely lift the lockdowns (namely, sustained mitigation, zonal lockdown and rolling lockdown strategies), and (2) propose suitable application, pre-requisites, and inherent limitations for each measure. Transmission hotspots, or red zones are subject to strict lockdown measures than green zones, where very few or no new cases have been identified for several days.
    keywords: cases; countries; covid-19; health; lmics; lockdown; measures; strategy; zones
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        item: #4135 of 7819
          id: cord-306293-miyc5kok
      author: Sherman, Courtney B
       title: In‐Person Outreach and Telemedicine in Liver and Intestinal Transplant: A Survey of National Practices, Impact of COVID‐19 and Areas of Opportunity
        date: 2020-08-09
       words: 1625
      flesch: 41
     summary: Given the coronavirus disease 2019 (COVID‐19) pandemic, we distributed a second survey wave in April 2020 to assess changes in telemedicine use. During the COVID‐19 pandemic, among 55 of the 73 original responding programs (75%) from all 11 OPTN regions, telemedicine use increased from 16% to 98% and was used throughout all phases of transplant care.
    keywords: care; telemedicine; transplant; use
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        item: #4136 of 7819
          id: cord-306322-vx1fqtl5
      author: Wang, Yuanyuan
       title: Health care and mental health challenges for transgender individuals during the COVID-19 pandemic
        date: 2020-05-20
       words: 461
      flesch: 33
     summary: key: cord-306322-vx1fqtl5 authors: Wang, Yuanyuan; Pan, Bailin; Liu, Ye; Wilson, Amanda; Ou, Jianjun; Chen, Runsen title: Health care and mental health challenges for transgender individuals during the COVID-19 pandemic date: 2020-05-20 journal: Lancet Diabetes Endocrinol DOI: 10.1016/s2213-8587(20)30182-0 sha: doc_id: 306322 cord_uid: vx1fqtl5 nan Previous studies showed that genderaffirming surgery was associated with reduced mental health problems. Transgender health: access to care under threat Health care and mental wellbeing in the transgender and gender-diverse Chinese population COVID-19 policies can perpetuate violence against transgender communities: insights from Peru Reduction in mental health treatment utilization among transgender individuals after gender-affirming surgeries: a total population study Vaginoplasty complications
    keywords: health; transgender
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        item: #4137 of 7819
          id: cord-306342-wwinyu7x
      author: Marano, Luigi
       title: Cancer care under the outbreak of COVID-19: A perspective from Italian tertiary referral center for surgical oncology
        date: 2020-04-15
       words: 833
      flesch: 36
     summary: The Italian hospitals should be reorganized modifying the architecture and creating two wide shelters, a dedicated self-contained COVID-19 area and a clean area for COVID-19 negative patients requiring routine care including emergency surgery and urgent oncological procedures. On the same line, it is imperative to provide general recommendations within a tertiary referral center for surgical oncology for maintaining high quality cancer care in an extremely safe working environment.
    keywords: covid-19; outbreak; patients
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        item: #4138 of 7819
          id: cord-306347-gmw3z85r
      author: Maniscalco, Pietro
       title: The deep impact of novel CoVID-19 infection in an Orthopedics and Traumatology Department: the experience of the Piacenza Hospital
        date: 2020-05-11
       words: 3421
      flesch: 48
     summary: Hyperinflammatory reaction and microvascular pulmonary thrombosis seem to be the cause of multiorgan failure and death in CoVID-19 patients (4) . As result, the sudden and massive wave of CoVID-19 patients in such a short time of period has paralyzed our health system and hospital organization.
    keywords: covid-19; department; emergency; hospital; italy; patients; piacenza; pneumonia
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        item: #4139 of 7819
          id: cord-306351-ka6asw3m
      author: Alsuliman, Tamim
       title: A review of potential treatments to date in COVID-19 patients according to the stage of the disease
        date: 2020-05-30
       words: 6067
      flesch: 42
     summary: key: cord-306351-ka6asw3m authors: Alsuliman, Tamim; Alasadi, Lugien; Alkharat, Banan; Srour, Micha; Alrstom, Ali title: A review of potential treatments to date in COVID-19 patients according to the stage of the disease date: 2020-05-30 journal: Curr Res Transl Med DOI: 10.1016/j.retram.2020.05.004 sha: doc_id: 306351 cord_uid: ka6asw3m Abstract Introduction and motivation: Since the end of 2019, the COVID-19 pandemic has affected millions of people worldwide. Since human safety data for Remdesivir are available from several clinical trials that tested Remdesivir's efficacy against Ebola virus, several clinical trials are already being held in the United States and China to investigate its efficacy treating COVID-19 patients [7, 26, 32] .
    keywords: coronavirus; cov-2; covid-19; data; disease; hcq; patients; pneumonia; sars; stage; study; treatment; trials; use
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        item: #4140 of 7819
          id: cord-306375-cs4s2o8y
      author: Costa-Santos, C.
       title: COVID-19 surveillance - a descriptive study on data quality issues
        date: 2020-11-05
       words: 5154
      flesch: 46
     summary: We aimed to assess data quality issues of COVID-19 surveillance data and suggest solutions to overcome them, using the Portuguese surveillance datasets as an example. Epidemiological surveillance systems need to be designed having data quality as a high priority and thus promoting, rather than relying on, users' efforts to ensure data quality [6] .
    keywords: cases; covid-19; data; dataset; dgsaugust; license; preprint; quality
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        item: #4141 of 7819
          id: cord-306377-s9j21zsy
      author: Yan, Li
       title: A machine learning-based model for survival prediction in patients with severe COVID-19 infection
        date: 2020-03-01
       words: 3469
      flesch: 50
     summary: We apply the following diagnostic criteria [4] : 1) Epidemiological history: Traveled or lived in Wuhan within 14 days before onset; Had contact with patients with fever and respiratory symptoms from Wuhan within 14 days before onset; Had contact with COVID-19 patients (positive for COVID-19 nucleic acid) within 14 days before onset; Or part of a familial cluster of onsets; 2) Clinical manifestations: Fever and/or respiratory symptoms; Normal or decreased total white blood cell count or decreased lymphocyte count during early stage of onset; Typical imaging features. After February 19th, 2020, there were 26 new cleared severe patients, which were thus picked for the test together with other 3 cleared severe patients from Ying Cheng People's Hospital for testing.
    keywords: covid-19; data; features; license; model; patients; preprint; set; xgboost
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        item: #4142 of 7819
          id: cord-306414-2dv3qced
      author: Gutierrez, Lucas
       title: Deciphering the TCR Repertoire to Solve the COVID-19 Mystery
        date: 2020-06-20
       words: 7001
      flesch: 34
     summary: TCR engineered T cell (TCR-T): T cells engineered by viral vectors to express the TCR gene with defined specificity. T cells, however, mature in the thymus, and CD8 + T cells kill virus-infected cells (cell-mediated antiviral response) through T cell receptor (TCR)-mediated recognition of viral antigens.
    keywords: antigen; cells; cov-2; covid-19; diversity; infection; patients; receptor; repertoire; response; sars; sequencing; tcr; tcr repertoire
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        item: #4143 of 7819
          id: cord-306421-r8wzvpn5
      author: Sizoo, Eefje M.
       title: Dilemmas with restrictive visiting policies in Dutch nursing homes during the COVID-19 pandemic: a qualitative analysis of an open-ended questionnaire with elderly care physicians
        date: 2020-10-23
       words: 3778
      flesch: 55
     summary: 122 ECPs noted that although protection against contamination was irrelevant for a resident in 123 the dying phase, protection of other residents in the institution, health care providers, next-124 of-kin and society remained notwithstanding important (quote 22). However, given the diversity of NH residents, alternatives were often only suitable for some of them.
    keywords: care; covid-19; ecps; nhs; phase; residents; visitor
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        item: #4144 of 7819
          id: cord-306453-w1sxap5p
      author: Pierce-Williams, Rebecca A.M.
       title: Clinical course of severe and critical COVID-19 in hospitalized pregnancies: a US cohort study
        date: 2020-05-08
       words: 4584
      flesch: 45
     summary: However, current data in the COVID-19 pandemic suggests that pregnant women experience similar, or even lower, rates of severe disease as compared to non-pregnant individuals 3, 19 . Eighty-one percent of women were treated with hydroxychloroquine; 9% of women with severe disease and 65% of women with critical disease received remdesivir.
    keywords: course; covid-19; data; day; days; disease; infection; weeks; women
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        item: #4145 of 7819
          id: cord-306465-7kevsl1z
      author: Agarwal, Krishna Mohan
       title: Study and Overview of the Novel Corona Virus Disease (COVID-19)
        date: 2020-09-06
       words: 2649
      flesch: 43
     summary: key: cord-306465-7kevsl1z authors: Agarwal, Krishna Mohan; Mohapatra, Swati; Sharma, Prairit; Sharma, Shreya; Bhatia, Dinesh; Mishra, Animesh title: Study and Overview of the Novel Corona Virus Disease (COVID-19) date: 2020-09-06 journal: nan DOI: 10.1016/j.sintl.2020.100037 sha: doc_id: 306465 cord_uid: 7kevsl1z In December 2019, a new disease with pneumonia-like symptoms was spreading throughout Wuhan in China which was entitled as novel coronavirus disease or COVID -19 caused by the virus SARS CoV-2. India coronavirus numbers explained: Cases in four states growing faster than the national average Nearly 7 Lakh Coronavirus Cases In India Recent Advancements in the Diagnosis, Prevention, and Prospective Drug Therapy of COVID-19.
    keywords: cases; coronavirus; covid-19; disease; india; novel; pandemic; sars
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        item: #4146 of 7819
          id: cord-306466-y4yg42p8
      author: Nofal, Ahmed Maged
       title: Who complies with COVID-19 transmission mitigation behavioral guidelines?
        date: 2020-10-08
       words: 5729
      flesch: 33
     summary: Importantly, when adding controls in Model 2, we now find that extraversion negatively influences the tendency of people to comply with COVID-19 transmission mitigation behavioral guidelines, meanwhile agreeableness, conscientiousness, and openness to experience positively influence the tendency of people to Big five personality traits and COVID-19 behavioral guidelines While we are cautious about causality issues given the cross-sectional nature of our data, we emphasize that COVID-19 transmission mitigation behavioral guidelines are a result of an exogenous shock (i.e. the sudden outbreak of COVID-19). key: cord-306466-y4yg42p8 authors: Nofal, Ahmed Maged; Cacciotti, Gabriella; Lee, Nick title: Who complies with COVID-19 transmission mitigation behavioral guidelines? date: 2020-10-08 journal: PLoS One DOI: 10.1371/journal.pone.0240396 sha: doc_id: 306466 cord_uid: y4yg42p8 During the past 6 months, the world has lost almost 950,000 lives because of the outbreak of COVID-19, with more than 31 million individuals diagnosed with COVID-19 worldwide.
    keywords: covid-19; covid-19 transmission; guidelines; individuals; mitigation; people; personality; transmission; transmission mitigation
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        item: #4147 of 7819
          id: cord-306495-o0ah1gj9
      author: Haidar, Ghady
       title: COVID-19, organ transplantation, and the nuances of immunomodulation: lessons learned and what comes next
        date: 2020-08-11
       words: 1264
      flesch: 35
     summary: Sepsis Cryptococcus neoformans in organ transplant recipients: impact of calcineurin-inhibitor agents on mortality Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Additionally, transplant patients frequently suffer from the same comorbidities that have been associated with detrimental outcomes in COVID-19.
    keywords: covid-19; recipients; sot; transplant
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        item: #4148 of 7819
          id: cord-306536-tkjg6iu0
      author: Tang, P. M.
       title: Geographical identification of the vulnerable groups during COVID-19 crisis: the typhoon eye effect and its boundary conditions
        date: 2020-05-02
       words: 3540
      flesch: 54
     summary: Meanwhile, our results indicate the practitioners should be cautious of using typhoon eye effect for individuals who were older or had a larger family size. The distance of individual adults to the epicenter was negatively associated with life satisfaction ({beta} = -0.235, 95% CI -0.450 to -0.020, p = 0.032).
    keywords: covid-19; epicenter; license; life; medrxiv; preprint; satisfaction
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        item: #4149 of 7819
          id: cord-306551-qf7h9m78
      author: Han, Heesup
       title: The Post-Coronavirus World in the International Tourism Industry: Application of the Theory of Planned Behavior to Safer Destination Choices in the Case of US Outbound Tourism
        date: 2020-09-06
       words: 6922
      flesch: 37
     summary: Under the worldwide COVID-19 pandemic situation, this study focused on international tourism behaviors. In sum, the theoretical premise of this research in the international tourism sector is that the travelers who have strong knowledge of COVID-19 are likely to form a positive attitude toward safer destination choice behaviors and to perceive the social norm to practice the action, which leads to the increased intention to engage in the behavior in conjunction with the perceived behavioral control.
    keywords: attitude; behavior; covid-19; intention; model; norm; risk; tourism; travelers
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        item: #4150 of 7819
          id: cord-306567-44w6op7p
      author: Krittanawong, Chayakrit
       title: Misinformation dissemination in Twitter in the COVID-19 era
        date: 2020-08-14
       words: 1255
      flesch: 36
     summary: We identified seven important categories of individuals' attributions of COVID-19; 1) influenza vaccine could lead to positive COVID test results (11.5%); 2) the attribution of influenza deaths or cases to COVID19 (5.9%); 3) prior influenza infections could cause a positive COVID test (2.8%); 4) influencers' that quoted Flu shot leads to positive COVID test (1.7%); 5) 5G networks could be a link to COVID-19 cases or symptoms (14.2%): 6) 5G is used to track individuals with a vaccine (5.5%); and 7) specific activities or seasonal effects causing allergies which is not COVID-19 infection (2.8%). There is no evidence suggesting that prior influenza infection may lead to a higher susceptibility of COVID-19 infection.
    keywords: covid-19; infection; influenza; twitter
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        item: #4151 of 7819
          id: cord-306585-kdlv46tq
      author: Zhang, Z.
       title: Dynamical balance between the transmission, intervention of COVID-19 and economic development
        date: 2020-08-15
       words: 2539
      flesch: 48
     summary: To fill the knowledge gap, a new coupled model of COVID-19 transmission and economic growth is established by ordinary differential equations. The results indicate that there is a mutual restraining mechanism between COVID-19 transmission and economic growth.
    keywords: covid-19; disease; economy; growth
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        item: #4152 of 7819
          id: cord-306599-oedkaf75
      author: Gumina, Stefano
       title: The impact of COVID-19 on shoulder and elbow trauma. An Italian survey
        date: 2020-05-20
       words: 1871
      flesch: 55
     summary: In the no-COVID and COVID period, patients with shoulder contusion were 60 (14.78% of all) (M:34; F:26) (mean age: 51.8yrs; range: 18-88) and 11 (12.09% of all contusions) (M:7; F:4) (mean age: 43yrs; range: 24-60), respectively. In the no-COVID and COVID period, patients to whom a diagnosis of shoulder contusion was 103 formulated were 60 (14.78% of the 406 contusions occurred on the whole body) (M:34; F:26)
    keywords: covid; elbow; period; shoulder
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        item: #4153 of 7819
          id: cord-306646-6c7n0xir
      author: Crimi, Claudia
       title: Resumption of Respiratory Outpatient Services in the COVID-19 era: experience from Southern Italy
        date: 2020-07-02
       words: 1249
      flesch: 41
     summary: The Sars-CoV-2 infection is mainly transmitted by respiratory droplets 3 and close contact, and both respiratory clinicians and patients are at increased risk for transmission during the outpatient visit and the pulmonary function testing procedures. Patients scheduled for an outpatient visit may also suffer from common respiratory symptoms that can mimic or represent undiagnosed cases of COVID-19.
    keywords: covid-19; date; function; outpatient; patients
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        item: #4154 of 7819
          id: cord-306652-e9zvyftn
      author: Eng, Oliver S.
       title: Apples to Oranges: Ethical Considerations in COVID-19 Surgical Recovery
        date: 2020-05-20
       words: 517
      flesch: 42
     summary: Ann Surg DOI: 10.1097/sla.0000000000004082 sha: doc_id: 306652 cord_uid: e9zvyftn nan Phone: +1 (773) 702-4897 Fax: +1 (773) 702-6120 As the COVID-19 pandemic approaches peak incidence in many areas, recovery and emergence plans including the re-initiation of surgical cases are underway. Keywords: COVID-19, recovery, surgical ethics As the COVID-19 pandemic approaches peak incidence in many areas, recovery and emergence plans including the re-initiation of surgical cases are underway.
    keywords: covid-19; pandemic
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        item: #4155 of 7819
          id: cord-306670-c2jm0g88
      author: Zhang, Yan
       title: Association of Diabetes Mellitus with Disease Severity and Prognosis in COVID-19: A Retrospective Cohort Study
        date: 2020-05-22
       words: 3136
      flesch: 38
     summary: Other laboratory findings showed no significant differences between the two groups of patients with respect to serum levels of CRP, PCT, and LDH, but COVID-19 patients Next, we compared the severity, treatment, and short-term prognosis of the COVID-19 patients with and without diabetes in Table 3 . The laboratory findings on admission showed that leucocytes and neutrophils count and the proportion of increased leucocytes were higher in COVID-19 patients with diabetes than those without, which might be explained by the fact that patients with diabetes were more susceptible to pathogens after a viral infection due to lower immune function.
    keywords: china; clinical; covid-19; diabetes; disease; patients; prognosis; study
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        item: #4156 of 7819
          id: cord-306685-w7y5g2x0
      author: Chalk, D.
       title: Modelling Palliative and End of Life resource requirements during COVID-19: implications for quality care
        date: 2020-07-24
       words: 3978
      flesch: 46
     summary: https://doi.org/10.1101/2020.07.23.20160564 doi: medRxiv preprint Patients are allocated a bundle of EoL care resources, each of which has a probability of being selected, and a duration for their EoL care, sampled from an exponential distribution. For For patients in care homes, those in residential homes would typically require the highest level of EoL care resource because of the lack of internal nursing support.
    keywords: care; covid-19; eol; medrxiv; model; palliative; preprint; resource
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        item: #4157 of 7819
          id: cord-306690-s5mxes4r
      author: Shangguan, Ziheng
       title: What Caused the Outbreak of COVID-19 in China: From the Perspective of Crisis Management
        date: 2020-05-08
       words: 8712
      flesch: 47
     summary: In public health crisis management, five factors are usually considered [21] The five commonly considered factors in public health crisis management are a useful framework to analyze the problems and major causes of the COVID-19 crisis in China.
    keywords: china; chinese; covid-19; crisis; crisis management; government; health; information; january; management; public; wuhan
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        item: #4158 of 7819
          id: cord-306700-sz3bji8c
      author: Gandhi, Abhay Jayprakash
       title: An Ayurvedic Perspective along with in Silico Study of the Drugs for the Management of Sars-Cov-2
        date: 2020-07-21
       words: 1443
      flesch: 51
     summary: Thus, from the above results obtained from reviewing Ayurveda classics and after the virtual screening of selected drugs we can conclude that Nagaraadi Kashaya(Sunthi, Puskarmoola, Kantakari, Guduchi) may have appreciable results in combating SARS-COV-2. Thus, from the above results obtained from reviewing Ayurveda classics and after the virtual screening of selected drugs we can conclude that Nagaraadi Kashaya may have appreciable results in combating SARS-COV-2.
    keywords: ayurveda; covid; disease; drugs; study
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        item: #4159 of 7819
          id: cord-306718-7wp5jmxe
      author: Remaeus, Katarina
       title: Characteristics and short‐term obstetric outcomes in a case series of 67 women tested positive for SARS‐CoV‐2 in Stockholm, Sweden
        date: 2020-09-27
       words: 2558
      flesch: 50
     summary: In this case series of 67 test-positive women few women presented with severe COVID-19 illness, a majority had a vaginal birth at term with a healthy neonate that were test-negative for SARS-CoV-2. SARS-CoV-2 Infection in Pregnancy -a Review of the Current Literature and Possible Impact on Maternal and Neonatal Outcome Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know Infections in pregnancy with COVID-19 and other respiratory RNA virus diseases are rarely, if ever, transmitted to the fetus: experiences with coronaviruses, HPIV, hMPV RSV, and INFLUENZA Coronavirus disease 2019 among pregnant Chinese women: Case series data on the safety of vaginal birth and breastfeeding COVID-19 in pregnancy with comorbidities: More liberal testing strategy is needed Covid-19: risk factors for severe disease and death The Swedish Pregnancy Registerfor quality of care improvement and research The Swedish Pregnancy Register. Concerns have been raised regarding risks for severe disease in pregnant women, preterm delivery, possible vertical transmission, and neonatal infection.
    keywords: birth; cov-2; covid-19; sars; women
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        item: #4160 of 7819
          id: cord-306721-18tmaw2i
      author: Thorne, C.J.
       title: COVID-19 Resuscitation guidelines: a blanket rule for everyone?
        date: 2020-06-20
       words: 632
      flesch: 35
     summary: key: cord-306721-18tmaw2i authors: Thorne, C.J.; Ainsworth, M. title: COVID-19 Resuscitation guidelines: a blanket rule for everyone? date: 2020-06-20 journal: Resuscitation DOI: 10.1016/j.resuscitation.2020.06.013 sha: doc_id: 306721 cord_uid: 18tmaw2i nan Thorne CJ 1 , Ainsworth M 1 To the Editor, The COVID-19 pandemic has had a profound impact on the management of both in-hospital and out of hospital cardiac arrest. Whilst in this particular case the patient had a good outcome, there is a risk of harm in future cases from the delayed initiation of resuscitation related to COVID-19 guidelines being applied outside of the context for which they were intended.
    keywords: covid-19; resuscitation
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        item: #4161 of 7819
          id: cord-306729-oa9i4ss9
      author: Luo, Li-Sha
       title: COVID-19: Presumed Infection Routes and Psychological Impact on Staff in Administrative and Logistics Departments in a Designated Hospital in Wuhan, China
        date: 2020-06-12
       words: 3084
      flesch: 39
     summary: The current study thus aimed to explore the potential infection routes and psychological changes among hospital staff in ALDs and to provide scientific suggestions on preventing adverse effects among this population's during large-scale infectious diseases outbreaks. The results indicated that working in hospital and having clinical professional knowledge does not affect the psychological impact of COVID-19 epidemic on hospital staff.
    keywords: alds; covid-19; diagnosis; infection; members; staff
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        item: #4162 of 7819
          id: cord-306733-df36w6l7
      author: Rosales-Mendoza, Sergio
       title: What Does Plant-Based Vaccine Technology Offer to the Fight against COVID-19?
        date: 2020-04-14
       words: 8607
      flesch: 34
     summary: Another approach to express heterologous protein in plants relies on the use of viral-based vectors, which exploit the efficient promoters, UTRs, and DNA/RNA replication mechanisms found in plant viruses. A recent review revealed that at least 97 vaccine candidates have been developed based on plant viruses covering infectious agents, cancer, and autoimmune disorders [78] .
    keywords: antigen; approach; cells; coronavirus; cov-1; covid-19; development; expression; immune; mice; plant; production; protein; sars; vaccines; virus; vlps
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        item: #4163 of 7819
          id: cord-306748-i9ndb71n
      author: Kobia, Francis
       title: COVID-19: Are Africa’s diagnostic challenges blunting response effectiveness?
        date: 2020-04-17
       words: 3221
      flesch: 47
     summary: COVID-19 diagnostic testing is recommended for individuals that satisfy the suspect case definition (Leitmeyer et al., 2020). Here, based on the African situation, we discuss COVID-19 diagnostic challenges and how they may blunt responses.
    keywords: africa; cases; challenges; covid-19; diagnostic; testing
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        item: #4164 of 7819
          id: cord-306760-05my504t
      author: Turner, Dan
       title: Corona Virus Disease 2019 and Paediatric Inflammatory Bowel Diseases: Global Experience and Provisional Guidance (March 2020) from the Paediatric IBD Porto Group of European Society of Paediatric Gastroenterology, Hepatology, and Nutrition
        date: 2020-03-31
       words: 3841
      flesch: 42
     summary: A questionnaire was sent on March 20, 2020 to 19 paediatric gastroenterology centers in China to evaluate the impact of COVID-19 on the prognosis of IBD children. On the basis of currently (March 2020) available limited data presented here, we suggest the following: IBD children, with and without immunosuppressive and biological therapy, do not seem to carry a higher risk of SARS-CoV-2 infection, compared with the general population.
    keywords: cases; children; cov-2; covid-19; disease; group; ibd; infection; patients; sars
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        item: #4165 of 7819
          id: cord-306770-hjzlj8k3
      author: Mick, Paul
       title: Aerosol-generating otolaryngology procedures and the need for enhanced PPE during the COVID-19 pandemic: a literature review
        date: 2020-05-11
       words: 6321
      flesch: 39
     summary: There is an opportunity to perform research to quantify the risk of COVID-19 transmission from patients to health care workers performing aerosol-generating otolaryngology procedures during the COVID-19 pandemic. key: cord-306770-hjzlj8k3 authors: Mick, Paul; Murphy, Russell title: Aerosol-generating otolaryngology procedures and the need for enhanced PPE during the COVID-19 pandemic: a literature review date: 2020-05-11 journal: J Otolaryngol Head Neck Surg DOI: 10.1186/s40463-020-00424-7 sha: doc_id: 306770 cord_uid: hjzlj8k3 BACKGROUND: Adequate personal protective equipment is needed to reduce the rate of transmission of COVID-19 to health care workers.
    keywords: aerosol; care; covid-19; evidence; health; otolaryngology; patients; procedures; respirators; risk; sars; transmission; workers
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        item: #4166 of 7819
          id: cord-306790-82nltfk3
      author: Sheikh, Abu Baker
       title: Inferior Wall Myocardial Infarction in Severe COVID-19 Infection: A Case Report
        date: 2020-09-28
       words: 2025
      flesch: 37
     summary: There is an emerging need to streamline these presentations to improve the health care provided to COVID-19 patients by using a triage system to classify patients with severe symptoms and those at risk of complications. With the ever-increasing number of COVID-19 patients, it is imperative to explore the factors related to the disease to aid patient management until a definitive vaccine is ready, as the disease is not limited to the respiratory system alone.
    keywords: acute; covid-19; disease; infarction; patients; pneumonia
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        item: #4167 of 7819
          id: cord-306809-ugxuh7z4
      author: AKÇAY, Şule
       title: Radiological approaches to COVID-19 pneumonia
        date: 2020-04-21
       words: 1628
      flesch: 45
     summary: In our country, a national guideline was written in the light of the recent literature and COVID-19 pneumonia patients who recovered from COVID-19 pneumonia, 4 stages of lung involvement were defined on CT COVID-19 infection has been spreading globally.
    keywords: chest; covid-19; pneumonia
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        item: #4168 of 7819
          id: cord-306810-g64gjpbd
      author: Mendivelso Duarte, Fredy Orlando
       title: Recomendaciones para la reapertura de servicios de cirugía electiva durante la pandemia por SARS-CoV-2
        date: 2020-09-16
       words: 3117
      flesch: 41
     summary: En ambos casos, se requiere realizar de inmediato la investigación de campo para identificar los contactos efectivos en la institución y apoyarse con las autoridades de salud y de aseguramiento en la búsqueda activa, el tamizaje, la atención y la protección de contactos ambulatorios. Tanto la apertura como la decisión de suspender la programación de procedimientos de cirugía electiva se regirán por decisiones informadas con datos derivados del monitoreo diario institucional, contrastados y acatando las alertas dadas por las autoridades locales y nacionales.
    keywords: cada; casos; cirugía; como; con; covid-19; debe; del; durante; electiva; institución; las; los; pacientes; pandemia; para; por; procedimientos; que; salud; sars; servicios; una; uso
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        item: #4169 of 7819
          id: cord-306819-otabtxin
      author: Asensio-Samper, JM
       title: Recomendaciones Prácticas Para El Manejo Del Paciente Con Dolor Crónico Durante La Pandemia De COVID-19
        date: 2020-09-02
       words: 5170
      flesch: 34
     summary: no ha sido un aspecto relevante a considerar en tiempos de crisis, incluyendo los estados epidémicos, sin embargo el derecho de los pacientes al bienestar, los beneficios sociales y de estándares de salud pública inherentes al tratamiento del dolor, así como la responsabilidad de los proveedores de salud y cuidadores de proporcionar atención global a los pacientes incluyendo la analgesia adecuada, lo convierten en un aspecto fundamental. al máximo la circulación y estancia de los pacientes en las áreas asistenciales.
    keywords: acompañante; así; atención; casos; como; con; cov-2; covid-19; crónico; debe; del; dolor; durante; health; infección; las; los; opioides; paciente; pain; pandemia; para; patients; por; posible; presencial; procedimientos; que; riesgo; salud; sars; tratamiento; una
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        item: #4170 of 7819
          id: cord-306832-w8s282nq
      author: Tarragón, Blanca
       title: FRACASO RENAL AGUDO EN PACIENTES HOSPITALIZADOS POR COVID-19
        date: 2020-10-09
       words: 3473
      flesch: 45
     summary: Page 6 of 14 J o u r n a l P r e -p r o o f La gravedad de la infección por SARS-CoV-2 fue determinada según la clasificación de la OMS para COVID-19 y la escala CURB-65 15, 17 , considerándose como afectación pulmonar grave los cuadros de neumonía grave y de SDRA. Los datos de la infección por SARS-CoV-2 se recogen en la Tabla 2.
    keywords: afectación; casos; como; con; cov-2; covid-19; del; estudio; fra; fue; ingreso; las; los; más; pacientes; patients; por; que; renal; sars; una
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        item: #4171 of 7819
          id: cord-306835-juitltpi
      author: Babaei, Fatemeh
       title: Curcumin (a constituent of turmeric): New treatment option against COVID‐19
        date: 2020-09-06
       words: 6247
      flesch: 30
     summary: China Curcumin inhibits the replication of enterovirus 71 in vitro Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1 Curcumin attenuates allergen-induced airway hyperresponsiveness in sensitized guinea pigs Regulation of COX and LOX by curcumin ACE2 and pACE2: A pair of aces for pulmonary arterial hypertension treatment? Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis Curcumin downregulates human tumor necrosis factor-α levels: A systematic review and meta-analysis of randomized controlled trials Pinitol targets nuclear factor-kappaB activation pathway leading to inhibition of gene products associated with proliferation, apoptosis, invasion, and angiogenesis Hydro-ethanolic extract of Curcuma longa affects tracheal responsiveness and lung pathology in ovalbumin-sensitized rats The multifaceted role of curcumin in cancer prevention and treatment Activation of transcription factor NFkappa B is suppressed by curcumin (diferuloylmethane) Y-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model Pre-treatment with curcumin ameliorates cisplatin-induced kidney damage by suppressing kidney inflammation and apoptosis in rats Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review From SARS to MERS, thrusting coronaviruses into the spotlight Intranasal curcumin and its evaluation in murine model of asthma Understanding of COVID-19 based on current evidence Activation of SIRT1 by curcumin blocks the neurotoxicity of amyloid-β25-35 in rat cortical neurons Sina Hospital Covid-19 registry (SHCo-19R) Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells Targeting the renin-angiotensin system as novel therapeutic strategy for pulmonary diseases Pulmonary pathology of early-Phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer Effect of nuclear factor kappa B on intercellular adhesion molecule-1 expression and neutrophil infiltration in lung injury induced by intestinal ischemia/reperfusion in rats Renoprotective effect of the antioxidant curcumin: Recent findings Curcumin inhibits paraquat induced lung inflammation and fibrosis by extracellular matrix modifications in mouse model Protection from acute and chronic lung diseases by curcumin Clinical features and treatment of COVID-19 patients in northeast Chongqing Receptor recognition by the novel coronavirus from Wuhan: An analysis based on decade-long structural studies of SARS coronavirus Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Curcumin ameliorated ventilator-induced lung injury in rats Curcumin as a therapeutic agent for blocking NF-κB activation in ulcerative colitis Clinical features of 69 cases with coronavirus disease 2019 in Wuhan. Curcumin has low bioavailability, but a lot of data from clinical trials showed the high efficacy of curcumin or turmeric against several diseases (Kunnumakkara et al., 2019) .
    keywords: ace2; acute; cells; coronavirus; covid-19; curcumin; effects; et al; human; inflammatory; injury; lung; patients; protein; receptor; sars; treatment
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        item: #4172 of 7819
          id: cord-306856-swiskyuf
      author: Ducournau, F.
       title: COVID-19: Initial experience of an international group of hand surgeons
        date: 2020-04-09
       words: 1379
      flesch: 51
     summary: While the pandemic does not affect hand surgeons at first glance, they have a role to play. The purpose of this study was to describe the different measures that have been put in place in response to the COVID-19 pandemic by hand surgeons throughout the world.
    keywords: covid-19; measures; pandemic; surgeons
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        item: #4173 of 7819
          id: cord-306858-8ypafd3h
      author: da Silva, Flaviane Cristine Troglio
       title: Psychiatric symptomatology associated with depression, anxiety, distress, and insomnia in health professionals working in patients affected by COVID-19: A systematic review with meta-analysis
        date: 2020-08-07
       words: 3215
      flesch: 41
     summary: key: cord-306858-8ypafd3h authors: da Silva, Flaviane Cristine Troglio; Neto, Modesto Leite Rolim title: Psychiatric symptomatology associated with depression, anxiety, distress, and insomnia in health professionals working in patients affected by COVID-19: A systematic review with meta-analysis date: 2020-08-07 journal: Prog Neuropsychopharmacol Biol Psychiatry DOI: 10.1016/j.pnpbp.2020.110057 sha: doc_id: 306858 cord_uid: 8ypafd3h BACKGROUND: Health professionals are key personnel to containing infectious diseases like COVID-19.
    keywords: anxiety; covid-19; et al; health; professionals
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        item: #4174 of 7819
          id: cord-306881-wrd2rhjz
      author: Gehrie, Eric
       title: Transfusion Service Response to the COVID-19 Pandemic
        date: 2020-06-25
       words: 3300
      flesch: 35
     summary: 23 Providers also considered starting or increasing hydroxyurea in an effort to maintain lower levels of hemoglobin S. There were initially reports of TPE being done in COVID-19 patients with florid infections who developed sepsis, pneumonia, acute respiratory distress syndrome, and multisystem organ failure, most likely the result of cytokine storm with endothelial damage, inflammation, and hypercoagulability. This risk should be carefully weighed, especially when considering that the literature contains significant advocacy for extensive plasma exposure to COVID-19 patients, some with no actual patient experience to support the proposed practice.
    keywords: blood; convalescent; covid-19; disease; pandemic; patients; plasma; supply; treatment
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        item: #4175 of 7819
          id: cord-306916-4dqzuy4u
      author: Barré, Jean
       title: Montelukast Drug May Improve COVID-19 Prognosis: A Review of Evidence
        date: 2020-09-04
       words: 3301
      flesch: 24
     summary: MK also attenuated the initial responses to respiratory syncytial virus (RSV) infection in neonate and adult mice, and reduced the consequences of RSV reinfection in mice initially infected as neonates (Han et al., 2010; Kloepfer et al., 2011) . Finally, in humans, Morita et al. (2017) have reported a decrease of almost 50% in the number of colds in younger boys aged 1 to 5. SARS-CoV-2 interacts with the ACE2 receptors to infect the host (Bourgonje et al., 2020) .
    keywords: covid-19; et al; leukotriene; montelukast; patients; sars; virus
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        item: #4176 of 7819
          id: cord-306952-cpltrsa7
      author: de Souza, Pedro Mansueto Melo
       title: Validation of verbal autopsy and nasopharyngeal swab collection for the investigation of deaths at home during the COVID-19 pandemics in Brazil
        date: 2020-11-04
       words: 1245
      flesch: 36
     summary: It is a noteworthy fact that there were no confirmed cases of SARS-CoV-2 among home deaths in the last 5 weeks, which may represent both a decrease in the circulation of the Validation of verbal autopsy for the investigation of deaths at home during the COVID-19 virus as well as the reestablishment of the capacity of the health services of providing medical assistance to possible new cases of the disease. To fulfill its mission, SVO-RF performs complete diagnostic autopsies (CDA) for the investigation of deaths at home without medical assistance, as well as deaths without bona fide diagnosis prior to death
    keywords: covid-19; deaths; home; svo
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        item: #4177 of 7819
          id: cord-306958-8bx8kxxh
      author: Christensen, Sarah R.
       title: Political and personal reactions to COVID-19 during initial weeks of social distancing in the United States
        date: 2020-09-24
       words: 4276
      flesch: 41
     summary: This survey examined attitudes toward media, government, and community responses to COVID-19 by political ideology and sociodemographic factors. Questions assessed political ideology, scientific trust, and media consumption, as well as attitudes, anxieties, impacts, and knowledge related to COVID-19.
    keywords: covid-19; government; health; ideology; media; pandemic; respondents; u.s
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        item: #4178 of 7819
          id: cord-306997-84pjfawk
      author: Melazzini, Federica
       title: Venous thromboembolism and COVID-19: a single center experience from an academic tertiary referral hospital of Northern Italy
        date: 2020-11-08
       words: 3667
      flesch: 39
     summary: Since 100% of VTE patients had a Padua score greater than 4, we suggest performing upper and lower limb venous ultrasound in COVID-19 patients with a score > 4, as well as routinely in ICU patients to identify and treat DVT as soon as possible. Supplementary Table 1 shows characteristics and differences between VTE patients admitted to intensive care unit (ICU) and VTE general ward patients.
    keywords: clinical; covid-19; hospital; non; patients; risk; study; vte
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        item: #4179 of 7819
          id: cord-306999-bedygxjs
      author: Kurihara, Hayato
       title: Authors' response: Surgery in the coronavirus disease 2019 phase 2 Italian scenario: Lessons learned in northern Italy spoke hospitals
        date: 2020-07-01
       words: 1266
      flesch: 43
     summary: Despite HIVand HBV being blood-borne viruses, laparoscopic surgery is being performed in HIV and HBV patients for many years, and no clear demonstration is available of viral transmission through the pneumoperitoneum or surgical smoke. Not now during COVID-19 outbreak and not for acute care surgery and emergency colorectal surgery: a practical algorithm from a hub tertiary teaching hospital in northern Lombardy Safe management of surgical smoke in the age of COVID-19 Detecting hepatitis B virus in surgical smoke emitted during laparoscopic surgery Is surgical plume developing during routine LEEPs contaminated with high-risk HPV?
    keywords: care; covid-19; smoke; surgery
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        item: #4180 of 7819
          id: cord-307018-l2i499z3
      author: Antonio Reyes-Bueno, José
       title: Análisis de letalidad en pacientes con demencia neurodegenerativa por COVID-19
        date: 2020-07-28
       words: 3065
      flesch: 43
     summary: El ajuste de la normalidad de las variables continuas se confirmó con la prueba de Kolgomorov-Smirnov. Estos datos deben corroborarse con futuros estudios con un mayor número de pacientes con demencia y con COVID-19 para confirmar nuestros resultados, así como para identificar otros posibles factores de riesgo relacionados con la gravedad de COVID-19 en pacientes con demencia.
    keywords: casos; con; covid-19; del; demencia; entre; estudio; las; letalidad; los; mayor; pacientes; para; por; que; una
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        item: #4181 of 7819
          id: cord-307044-4czeehkq
      author: Liu, Jiaye
       title: Longitudinal Changes of Liver Function and Hepatitis B Reactivation in COVID‐19 Patients with Pre‐existing Chronic HBV Infection
        date: 2020-08-06
       words: 3520
      flesch: 43
     summary: Chronic HBV infection was determined on the basis of testing positive for HBsAg and/or HBV DNA at hospital admission and medical history of chronic HBV infection. However, to the best of our knowledge, no studies had been carried out on the impact of chronic HBV infection on the disease progression and liver function changes of COVID-19 patients, and how the SARS-CoV-2 infection in turn affects the course of chronic HBV infection.
    keywords: chronic; covid-19; hbv; infection; liver; patients; sars
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        item: #4182 of 7819
          id: cord-307070-tqxvu3pu
      author: Iqbal, Phool
       title: Should We Rely on Screening Tests for Further Management Alone in Polymerase Chain Reaction Negative COVID-19 Patients? A Case Series
        date: 2020-09-20
       words: 2764
      flesch: 47
     summary: Herein, we report our experience with COVID-19 patients who were tested multiple times using this system but were negative for the SARS-CoV-2 virus. The dilemma of a diagnosis based on less sensitive and specific tests or atypical presentations may cause complications due to delay in the management of COVID-19 patients.
    keywords: cov-2; covid-19; disease; infection; patients; pcr; test
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        item: #4183 of 7819
          id: cord-307087-zsbmaieg
      author: Aguiar de Sousa, Diana
       title: The Curious Case of the Missing Strokes During the COVID-19 Pandemic
        date: 2020-06-08
       words: 1388
      flesch: 42
     summary: Dr Elkind receives research support from the BMS-Pfizer Alliance for Eliquis and Roche outside the submitted work. COVID-19 and stroke -a global world stroke organization perspective Collateral effect of Covid-19 on stroke evaluation in the United States The impact of the COVID-19 epidemic on stroke care and potential solutions Acute stroke care is at risk in the era of COVID-19: experience at a comprehensive stroke center in Barcelona Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study Short term exposure to air pollution and stroke: systematic review and meta-analysis IPD-Work Consortium. Notably, the proportion of patients with stroke undergoing thrombolysis and thrombectomy remained stable, despite a 25% reduction in absolute numbers that is likely to be attributed to the drop in stroke admissions.
    keywords: covid-19; pandemic; patients; stroke
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        item: #4184 of 7819
          id: cord-307089-344rhiw0
      author: Marson, Fernando Augusto Lima
       title: Covid-19 in Brazil
        date: 2020-04-27
       words: 1948
      flesch: 40
     summary: In the early stages of COVID-19 disease, before community infection, the number of hospitalizations in the private system was higher than in public health system conforming with the disease origin and type of infection and its placement. In Brazil, the number of COVID-19 cases is increasing daily and by April 14 th , 2020, 23,955 positive cases have emerged.
    keywords: brazil; covid-19; deaths; number; patients
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        item: #4185 of 7819
          id: cord-307100-w33e2078
      author: Douedi, Steven
       title: Successful Maternal and Fetal Outcomes in COVID-19 Pregnant Women: An Institutional Approach
        date: 2020-07-27
       words: 1413
      flesch: 47
     summary: COVID-19 infection management in pregnant patients has been poorly defined and explained in the literature. What we know COVID-19) and pregnancy: What obstetricians need to know Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: A retrospective review of medical records Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia Successful maternal and fetal outcomes in COVID-19 pregnant women… © None.
    keywords: covid-19; day; patient
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        item: #4186 of 7819
          id: cord-307127-1kkpx108
      author: Gill, D.
       title: ACE inhibition and cardiometabolic risk factors, lung ACE2 and TMPRSS2 gene expression, and plasma ACE2 levels: a Mendelian randomization study
        date: 2020-04-14
       words: 5239
      flesch: 33
     summary: There was evidence of a positive association of genetic liability to type 2 diabetes mellitus with lung ACE2 gene expression in GTEx (p = 4x10-4) and with circulating plasma ACE2 levels in INTERVAL (p = 0.03), but not with lung ACE2 expression in the Lung eQTL Consortium study (p = 0.68). There was evidence of a positive association of genetic liability to type 2 diabetes mellitus with lung ACE2 gene expression in GTEx (p = 4x10 -4 ) and with circulating plasma ACE2 levels in INTERVAL (p = 0.03), but not with lung ACE2 expression in the Lung eQTL Consortium study (p = 0.68).
    keywords: ace2; angiotensin; association; covid-19; expression; genetic; levels; lung; plasma; risk; tmprss2; variants
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        item: #4187 of 7819
          id: cord-307128-wwjeu8ie
      author: Walz, Lucas
       title: Janus Kinase-Inhibitor and Type I Interferon Ability to Produce Favorable Clinical Outcomes in COVID-19 Patients: A Systematic Review and Meta-Analysis
        date: 2020-08-11
       words: 4396
      flesch: 39
     summary: medRxiv preprint studies complied with the inclusion criteria. Figure 1 presents the meta-analysis flow chart and Table 1 presents the designs and characteristics of included studies.
    keywords: covid-19; interferon; jak; license; medrxiv; medrxiv preprint; preprint; type
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        item: #4188 of 7819
          id: cord-307148-k1uo3fxm
      author: Bradshaw, Patrick C.
       title: COVID-19: Proposing a Ketone-Based Metabolic Therapy as a Treatment to Blunt the Cytokine Storm
        date: 2020-09-09
       words: 20848
      flesch: 35
     summary: Therefore, R-BHB may mitigate respiratory virus infection both by increasing LL-37 levels and by increasing NADPH levels [16] that protect LL-37 from inactivation. Increased NADPH levels also have been shown to stimulate antiviral immunity by decreasing the level of the NADPH sensor protein HSCARG, which is a negative regulator of NF-κB transcription.
    keywords: acid; activity; bhb; cells; covid-19; cytokine; decrease; diet; effects; expression; fat; function; gene; glucose; iav; increase; infection; inflammatory; inhibition; ketogenic; ketone; levels; lung; macrophages; metabolism; mice; mitochondrial; nadph; production; response; ros; sars; signaling; storm
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        item: #4189 of 7819
          id: cord-307160-1vz0gw1w
      author: Morais-Almeida, Mário
       title: COVID-19, asthma, and biologic therapies: What we need to know
        date: 2020-05-16
       words: 3565
      flesch: 31
     summary: Based on the information available, we are providing the current knowledge regarding the management of severe asthma patients with biologics during the COVID-19 pandemic. Biologic therapies should be used in severe asthma patients who qualify for them, in order to limit the need for OCS as much as possible (37).
    keywords: asthma; biologics; cov-2; covid-19; data; pandemic; patients; safety; sars
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        item: #4190 of 7819
          id: cord-307187-5blsjicu
      author: Missel, Malene
       title: A stoic and altruistic orientation towards their work: a qualitative study of healthcare professionals’ experiences of awaiting a COVID-19 test result
        date: 2020-11-11
       words: 5822
      flesch: 46
     summary: The study offers an in-depth understanding of the meaning of the waiting for the test result for COVID-19 infection from the HCPs' perspective and should be of interest to a broad readership and add knowledge to the growing COVID-19 evidence base and in developing supportive inetrventions targeted HCPs in such a pandemic. A sudden decrease in the number of HCPs because of quarantining or isolation due to COVID-19 infection would potentially overload the healthcare system and the capacity to treat either patients with coronavirus or patients with other serious conditions would be challenged [8] .
    keywords: coronavirus; covid-19; experiences; hcps; healthcare; infection; participants; result; study; test
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        item: #4191 of 7819
          id: cord-307207-xfu5d7dt
      author: Abbas, Ahmed M.
       title: COVID‐19 and maternal pre‐eclampsia; a synopsis
        date: 2020-06-15
       words: 751
      flesch: 42
     summary: That may give possible explanation for raised incidence of preterm and low birth weight in COVID-19 positive pregnant women. Moreover, maternal serum ferritin is much higher in pre-eclamptic women compared to normotensive pregnant women which reflects proved hyperinflammatory state.
    keywords: covid-19; pre; women
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        item: #4192 of 7819
          id: cord-307227-x6xketcn
      author: Martin, William R.
       title: Repurposing of FDA-Approved Toremifene to Treat COVID-19 by Blocking the Spike Glycoprotein and NSP14 of SARS-CoV-2
        date: 2020-09-10
       words: 4008
      flesch: 42
     summary: 6 Indeed, a crystal structure of the Ebola virus with bound toremifene indicates the interaction lies between the attachment (GP1) and fusion (GP2) protein subunits. 13 Further studies have been done using large databases, such as ZINC, 14 to test large compound libraries across multiple viral proteins.
    keywords: binding; cov-2; docking; interaction; potential; protein; sars; spike; structure; toremifene
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        item: #4193 of 7819
          id: cord-307229-wjx90xki
      author: da Silveira, Matheus Pelinski
       title: Physical exercise as a tool to help the immune system against COVID-19: an integrative review of the current literature
        date: 2020-07-29
       words: 8424
      flesch: 30
     summary: key: cord-307229-wjx90xki authors: da Silveira, Matheus Pelinski; da Silva Fagundes, Kimberly Kamila; Bizuti, Matheus Ribeiro; Starck, Édina; Rossi, Renata Calciolari; de Resende e Silva, Débora Tavares title: Physical exercise as a tool to help the immune system against COVID-19: an integrative review of the current literature date: 2020-07-29 journal: Clin Exp Med DOI: 10.1007/s10238-020-00650-3 sha: doc_id: 307229 cord_uid: wjx90xki Acute viral respiratory infections are the main infectious disease in the world. The practice of physical exercises acts as a modulator of the immune system.
    keywords: activation; activity; cells; coronavirus; cov-2; covid-19; cytokines; disease; exercise; infection; lymphocytes; patients; practice; response; sars; system; tissue
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        item: #4194 of 7819
          id: cord-307246-y6di9aum
      author: Chia, Pow-Li
       title: Rhythm blues in the time of coronavirus disease 2019 (COVID-19): how the cardiac electrophysiologist adapts to a viral pandemic in Singapore
        date: 2020-05-27
       words: 1491
      flesch: 39
     summary: We share our experience of significant cardiac rhythm abnormalities seen in COVID-19 patients in Singapore, how the viral pandemic has affected the cardiac electrophysiology and pacing service in a large acute care general hospital and the steps taken to alleviate the negative impact. We share our experience of significant cardiac rhythm abnormalities seen in COVID-19 patients, and how the viral pandemic has affected the cardiac electrophysiology and pacing (EP) service in a large acute care general hospital in Singapore and the steps taken to mitigate the negative impact.
    keywords: cardiac; covid-19; pandemic; patients; singapore
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        item: #4195 of 7819
          id: cord-307258-66lwpblq
      author: Li, Weixia
       title: Anesthesia Management and Perioperative Infection Control in Patients With the Novel Coronavirus
        date: 2020-03-29
       words: 3114
      flesch: 38
     summary: All anesthesia machines used in infected patients or those with unknown status should be treated using disinfection standards established for communicable fungi, viruses, and vegetative bacteria. The latter leads to an acceptable choice of materials and techniques for personal protection and prevention of cross-contamination to other patients and staff.
    keywords: anesthesia; care; coronavirus; covid-19; infection; novel; patients; pneumonia
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        item: #4196 of 7819
          id: cord-307273-pplky6g4
      author: Schrooyen, Loïc
       title: Homeless people hospitalized with COVID-19 in Brussels
        date: 2020-08-07
       words: 1008
      flesch: 38
     summary: We assessed the prevalence, incidence and outcome of homeless patients hospitalized in our institution with COVID-19 between 3 rd March and 26 th May 2020. Homeless patients were retrospectively identified based on systematic social inquiry performed upon admission.
    keywords: covid-19; homeless; patients; population
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        item: #4197 of 7819
          id: cord-307284-w693a2rm
      author: Flament, H.
       title: Outcome of SARS-CoV-2 infection linked to MAIT cell activation and cytotoxicity: evidence for an IL-18 dependent mechanism
        date: 2020-09-02
       words: 5376
      flesch: 51
     summary: Here, we studied the immune cell landscape, with emphasis on MAIT cells, in a cohort of 182 patients including patients at various stages of disease activity. SARS-CoV-2-infected macrophages activated MAIT cells in a cytokine-dependent manner involving an IFN-dependent early phase and an IL-18-induced later phase.
    keywords: author; copyright holder; funder; license; medrxiv preprint; peer review; preprint; september; version
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        item: #4198 of 7819
          id: cord-307285-bxy0zsc7
      author: Dar Odeh, Najla
       title: COVID-19: Present and Future Challenges for Dental Practice
        date: 2020-04-30
       words: 4713
      flesch: 40
     summary: Following the recommended cross-infection control procedures, spreading awareness based on evidence and not misconceptions, identifying emergency cases indicated for dental treatment, and practicing effective tele-dentistry when needed can all be helpful for dental patients and community as a whole. Realizing the severity of outcomes associated with this disease and its high rate of transmission, dentists were instructed by regulatory authorities, such as the American Dental Association, to stop providing treatment to dental patients except those who have emergency complaints.
    keywords: cases; covid-19; dental; dentists; drug; healthcare; infection; patients; treatment; virus
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        item: #4199 of 7819
          id: cord-307287-zpq6byml
      author: Poulsen, Nadia Nicholine
       title: Cyclosporine and COVID‐19: Risk or Favorable?
        date: 2020-08-10
       words: 4462
      flesch: 26
     summary: Two drugs have shown promising effect on COVID-19 patients, Remdesivir proved in a recent trial to reduce time to recovery, but had no effect on mortality 1 . The first group had a mortality of 50% and the second group only 12.5% thus supporting the idea that continuous use of cyclosporine might be beneficial in COVID-19 patients.
    keywords: coronavirus; covid-19; cyclosporine; disease; patients; recipients; replication; respiratory; sars; syndrome; transplant
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        item: #4200 of 7819
          id: cord-307291-2jhrd9ex
      author: Zhang, S. X.
       title: Beyond predicting the number of infections: predicting who is likely to be COVID negative or positive
        date: 2020-05-05
       words: 3159
      flesch: 56
     summary: Individuals who worked in the workplace had a 73·4% (OR: 0·734; 95% CI: 0·659 to 0·809; p = 0·000) likelihood of being COVID-19 negative, 20·4% (OR: 0·204; 95% CI: 0·130 to 0·279; p = 0·000) likelihood of being unsure, and 6·1% (OR: 0·061; 95% CI: 0·022 to 0·101; p = 0·002) likelihood of being COVID-19 positive. This study provides the first attempt to identify people at greater risk of COVID-19 infection, enabling more targeted infectious disease prevention and control, which are especially important in the ongoing shortage of COVID-19 testing.
    keywords: covid-19; license; likelihood; preprint
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        item: #4201 of 7819
          id: cord-307293-zp4oddrt
      author: McCoy, Liam G
       title: CAN-NPI: A Curated Open Dataset of Canadian Non-Pharmaceutical Interventions in Response to the Global COVID-19 Pandemic
        date: 2020-04-22
       words: 3588
      flesch: 40
     summary: In just over a month since the declaration of the COVID-19 global pandemic, we have assembled a comprehensive dataset of non-pharmaceutical interventions at the national and subnational level in Canada (which we will continue to update at two-week intervals throughout the pandemic). https://doi.org/10.1101/2020.04.17.20068460 doi: medRxiv preprint Open access epidemiologic data and an interactive dashboard to monitor the COVID-19 outbreak in Canada Impact of non-pharmaceutical interventions (NPIs) to reduce COVID19 mortality and healthcare demand Non-pharmaceutical interventions for pandemic influenza, national and community measures Interventions to mitigate early spread of SARS-CoV-2 in Singapore: a modelling study.
    keywords: canada; covid-19; dataset; interventions; license; npis; pandemic; preprint
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        item: #4202 of 7819
          id: cord-307309-s0t4kp2x
      author: Liang, Ying
       title: Symptoms, Management and Healthcare Utilization of COPD Patients During the COVID-19 Epidemic in Beijing
        date: 2020-10-14
       words: 3016
      flesch: 41
     summary: A recent report from American Thoracic Society Patient Education emphasized that an action plan for COPD patients is important and helps patients to manage the lung condition and monitor the symptoms. Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the global burden of disease study 2017 Chronic obstructive pulmonary disease in China: a nationwide prevalence study Determinants of smoking cessation in patients with COPD treated in the outpatient setting Smoking cessation in chronic obstructive pulmonary disease patients aged 40 years or older in China Seasonal and regional variations in chronic obstructive pulmonary disease exacerbation rates in adults without cardiovascular risk factors All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas; took part in drafting, revising or critically reviewing the article; gave final approval of the version to be published; have agreed on the journal to which the article has been submitted; and agree to be accountable for all aspects of the work.
    keywords: copd; covid-19; disease; epidemic; patients; symptoms
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        item: #4203 of 7819
          id: cord-307313-sox12zfo
      author: Kalaitzaki, Argyroula E.
       title: The healthcare professionals amidst COVID-19 pandemic: A perspective of resilience and posttraumatic growth
        date: 2020-05-15
       words: 767
      flesch: 34
     summary: How should US hospitals prepare for coronavirus disease 2019 (COVID-19) Factors associated with mental health outcomes among health care workers exposed to coronavirus disease Resilience in caregivers: A systematic review A novel coronavirus outbreak of global health concern Coronavirus disease 2019 (COVID-19): situation report Declaration of interests: We declare no competing interests. Healthcare professionals are at the front-line of this crisis and are those who are actively engaged in the process of providing care for patients with COVID-19 while managing critical issues daily (e.g., lack of hospital facilities, personal protection measures, exhausting working hours, fear of contagion and spreading the virus).Most of the reports and studies have examined the obvious negative outcomes on health professionals, such as increased levels of stress, anxiety and depression (Lai et al., 2020) .
    keywords: health; professionals
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        item: #4204 of 7819
          id: cord-307322-h7vqmlq9
      author: Gongalsky, Maxim B
       title: Early detection of superspreaders by mass group pool testing can mitigate COVID-19 pandemic
        date: 2020-04-27
       words: 3617
      flesch: 54
     summary: key: cord-307322-h7vqmlq9 authors: Gongalsky, Maxim B title: Early detection of superspreaders by mass group pool testing can mitigate COVID-19 pandemic date: 2020-04-27 journal: nan DOI: 10.1101/2020.04.22.20076166 sha: doc_id: 307322 cord_uid: h7vqmlq9 Background Most of epidemiological models applied for COVID-19 do not consider heterogeneity in infectiousness and impact of superspreaders, despite the broad viral loading distributions amongst COVID-19 positive people (1-1 000 000 per mL). The model suggests that the person got COVID-19 positive test was admitted to hospital or quarantined at home and stopped transmission of the infection.
    keywords: covid-19; figure; model; people; preprint; red; superspreaders; testing
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        item: #4205 of 7819
          id: cord-307329-gfwllo1r
      author: Bahtiyar, Mert Ozan
       title: Fetal Interventions in the Setting of COVID-19 Pandemic: Statement from the North American Fetal Therapy Network (NAFTNet)
        date: 2020-04-26
       words: 688
      flesch: 44
     summary: key: cord-307329-gfwllo1r authors: Bahtiyar, Mert Ozan; Baschat, Ahmet; Deprest, Jan; Emery, Stephen; Goodnight, William; Johnson, Anthony; McCullough, Laurence; Moldenhauer, Julie; Ryan, Greg; Tsao, KuoJen; Van Mieghem, Tim; Wagner, Amy; Zaretsky, Michael title: Fetal Interventions in the Setting of COVID-19 Pandemic: Statement from the North American Fetal Therapy Network (NAFTNet) date: 2020-04-26 journal: Am J Obstet Gynecol DOI: 10.1016/j.ajog.2020.04.025 sha: doc_id: 307329 cord_uid: gfwllo1r nan Key words: fetal therapy, COVID-19, SARS-CoV-2, prenatal diagnosis, fetal intervention 44 to balance the risks and benefits of care provision, as we adapt our established practice in the 46 setting of the COVID-19 (SARS-CoV-2 infection) pandemic 1, 2 . Fetal therapy centers must carefully consider whether they can still offer certain, highly 130 resource intensive, fetal procedures, if their staffing becomes depleted, either due to 131 illness or deployment to other intensive care areas.
    keywords: covid-19; fetal
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        item: #4206 of 7819
          id: cord-307334-6rn69sne
      author: Sullivan, Ryan J
       title: COVID-19 and immune checkpoint inhibitors: initial considerations
        date: 2020-05-19
       words: 1753
      flesch: 34
     summary: Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Patients with cancer appear more vulnerable to SARS-COV-2: a multi-center study during the COVID-19 outbreak Do patients with cancer have a poorer prognosis of COVID-19? an experience in Risk of COVID-19 for patients with cancer Risk of COVID-19 for cancer patients Immune-Related adverse events associated with immune checkpoint blockade Immune checkpoint inhibitor toxicity Fatal toxic effects associated with immune checkpoint inhibitors: a systematic review and metaanalysis The PD-1/PD-L1 axis and virus infections: a delicate balance Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19) Pembrolizumab treatment for progressive multifocal leukoencephalopathy Interference of the T cell and antigen-presenting cell costimulatory pathway using CTLA4-Ig (abatacept) prevents staphylococcal enterotoxin B pathology Toxic shock syndrome toxin-1-induced death is prevented by CTLA4Ig A case report of clonal EBV-like memory CD4 + T cell activation in fatal checkpoint inhibitor-induced encephalitis Demographic factors associated with toxicity in patients treated with anti-programmed cell
    keywords: cancer; covid-19; ici; patients; therapy
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        item: #4207 of 7819
          id: cord-307340-00m2g55u
      author: Gerasimov, A.
       title: Reaching collective immunity for COVID-19: an estimate with a heterogeneous model based on the data for Italy
        date: 2020-05-25
       words: 2252
      flesch: 41
     summary: Coronavirus disease 2019 (COVID-19): situation report Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic Preliminary identification of potential vaccine targets for the COVID-19 coronavirus (SARS-CoV-2) based on SARS-CoV immunological studies The COVID-19 vaccine development landscape Developing Covid-19 vaccines at pandemic speed Global dynamics of an SEIR epidemic model with vertical transmission Global dynamics of an SEIR epidemic model with saturating contact rate Herd immunity-estimating the level required to halt the COVID-19 epidemics in affected countries Herd immunity: a rough guide Herd immunity and herd effect: new insights and definitions Predicting the ultimate outcome of the COVID-19 outbreak in Italy A phased lift of control: a practical strategy to achieve herd immunity against Covid-19 at the country level Clinical features of COVID-19 in elderly patients: A comparison with young and middle-aged patients Are children less susceptible to COVID-19 A contribution to the mathematical theory of epidemics Sequential Lifting of COVID-19 Interventions with Population Heterogeneity Restarting the economy while saving lives under Covid-19 Comparison of different exit scenarios from the lock-down for COVID-19 epidemic in the UK and assessing uncertainty of the predictions Heterogeneous social interactions and the COVID-19 lockdown outcome in a multi-group SEIR model Early dynamics of transmission and control of COVID-19: a mathematical modelling study. Because of the high heterogeneity of COVID-19 infection risk across the different age groups, with a higher susceptibility for the elderly, homogeneous models overestimate the level of collective immunity needed for the disease to stop spreading.
    keywords: covid-19; epidemic; immunity; model
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        item: #4208 of 7819
          id: cord-307342-3gkiukh4
      author: Clark, Eva
       title: Why contact tracing efforts have failed to curb COVID-19 transmission in much of the U.S
        date: 2020-08-06
       words: 3274
      flesch: 48
     summary: key: cord-307342-3gkiukh4 authors: Clark, Eva; Chiao, Elizabeth Y; Amirian, E Susan title: Why contact tracing efforts have failed to curb COVID-19 transmission in much of the U.S date: 2020-08-06 journal: Clin Infect Dis DOI: 10.1093/cid/ciaa1155 sha: doc_id: 307342 cord_uid: 3gkiukh4 By late April 2020, public discourse in the U.S. had shifted toward the idea of using more targeted case-based mitigation tactics (e.g., contact tracing) to combat COVID-19 transmission while allowing for the safe “re-opening” of society, in an effort to reduce the social, economic, and political ramifications associated with stricter approaches. [6] , focusing on expanded testing and contact tracing, while disregarding several major obstacles that set us apart from countries that succeeded in mounting a timely, targeted response.
    keywords: contact; covid-19; health; public; testing
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        item: #4209 of 7819
          id: cord-307378-cx1jz7wf
      author: Dadar, Maryam
       title: The association between the incidence of COVID-19 and the distance from the virus epicenter in Iran
        date: 2020-09-02
       words: 2340
      flesch: 43
     summary: COVID-19 has spread to all 31 Iranian provinces, and the city of Tehran, the densely populated capital with over 13 million people located 150 km northeast of Qom, leads the country in COVID-19 cases ( Table 1) . The incidence rate for each province was calculated as the number of COVID-19 cases diagnosed until 23 March 2020 divided by the population of the province in 2019 and multiplied by 100,000.
    keywords: covid-19; incidence; iranian; population; provinces
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        item: #4210 of 7819
          id: cord-307406-59yh48tt
      author: de Loyola, Mariana Braccialli
       title: Alpha‐1‐antitrypsin: A possible host protective factor against Covid‐19
        date: 2020-08-26
       words: 5791
      flesch: 38
     summary: In addition, clinical findings indicate that A1AT levels might be important in defining Covid‐19 outcomes, potentially partially explaining associations with air pollution and with diabetes. [4] [5] [6] Moreover, recent data indicate that lower IL-6:A1AT levels are related to worse prognosis in This review addresses the interplay between A1AT, TMPRSS2, ADAM17, and inflammatory molecules during SARS-CoV-2 infection with the aim of identifying new avenues for effective treatments against Covid-19.
    keywords: ace2; adam17; antitrypsin; cells; cov-2; covid-19; infection; levels; lung; patients; protein; pulmonary; sars; tmprss2; tnf
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        item: #4211 of 7819
          id: cord-307416-v2296g5p
      author: Joob, Beuy
       title: Pulmonary Pathology of Early Phase 2019 Novel Coronavirus Pneumonia
        date: 2020-04-24
       words: 444
      flesch: 41
     summary: 1 Tian et al. 1 concluded that the lungs of both patients exhibited edema, proteinaceous exudate, focal reactive hyperplasia of pneumocytes with patchy inflammatory cellular infiltration, and multinucleated giant cells and noted that these changes likely represent an early phase of the lung pathology of COVID-19 pneumonia. Although this pathologic finding might be a lung abnormality in COVID-19, it should not be referred to as COVID-19 pneumonia because the patients did not have pneumonia.
    keywords: pneumonia
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        item: #4212 of 7819
          id: cord-307421-8ev8k9ok
      author: Li, Chenxi
       title: A 3-month-old child with COVID-19: A case report
        date: 2020-06-05
       words: 1752
      flesch: 48
     summary: [9] The risk factors for severe disease in children is still uncertain due to the small number of severe cases reported in children. COVID-19 case severity in children is classified as mild (asymptomatic or subclinical), normal, severe, and critical.
    keywords: children; coronavirus; covid-19; patient
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        item: #4213 of 7819
          id: cord-307426-fkzk8ubd
      author: Su, Zheng
       title: The Critical Role of Futility Analysis in the Pursuit of Effective Treatments for COVID-19
        date: 2020-06-09
       words: 806
      flesch: 35
     summary: The tradeoff between the cost of futility interim monitoring, which is a slight loss of study power, and allocating limited resources to more promising experimental treatments should be carefully considered by the study sponsor, the IRB and the DMC in the pursuit of safe and effective treatments for COVID-19. In addition, DMCs should consider reviewing interim data more frequently than specified in the protocol, and consider adding additional futility analyses when the results at a pre-specified interim analysis are trending towards futility instead of waiting for the next pre-specified analysis.
    keywords: futility; hydroxychloroquine
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        item: #4214 of 7819
          id: cord-307477-yddx2585
      author: Kolani, Sylvie
       title: Spontaneous pneumomediastinum occurring in the SARS-COV-2 infection
        date: 2020-05-11
       words: 1540
      flesch: 37
     summary: A benign curiosity or a significant problem Subcutaneous and mediastinal emphysema: pathophysiology, diagnosis and management Spontaneous pneumomediastinum: A 10 years' experience of a pulmonology ward Pneumomediastinum and subcutaneous emphysema associated with pandemic (H1N1) influenza in three children Spontaneous pneumomediastinum, pneumothorax, and subcutaneous emphysema Complicating H1N1 Virus Infection Pneumomediastinum and subcutaneous emphysema associated with influenza A H1N1 virus Management of pneumomediastinum associated with H1N1 pneumonia: a case report Spontaneous pneumomediastinum in H1N1 infection: uncommon complication of a common infection Molecular pathology of emerging coronavirus infections COVID-19 with spontaneous pneumomediastinum Spontaneous pneumomediastinum in COVID-19 pneumonia At our knowledge, two cases of spontaneous pneumomediastinum in COVID-19 patients have been reported.
    keywords: covid-19; infection; pneumomediastinum
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        item: #4215 of 7819
          id: cord-307481-h7xvehvk
      author: Abbas, Ahmed M.
       title: A focused review on the genital and sexual affection of COVID-19 patients
        date: 2020-06-30
       words: 1256
      flesch: 52
     summary: Additionally, a study in China showed that sexual activity declined among young men and women Nevertheless, a survey on lockdown circumstances and its effect on sexual activity in Bangladesh, India & Nepal show that 3.3% increase in sexual activity of participants from 1-5 times a week to more than five times [5] .
    keywords: coronavirus; covid-19; disease; patients
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        item: #4216 of 7819
          id: cord-307496-1k3d3o2q
      author: Meraj, Gowhar
       title: Coronavirus pandemic versus temperature in the context of Indian subcontinent: a preliminary statistical analysis
        date: 2020-07-10
       words: 3694
      flesch: 40
     summary: Contrary to Maharashtra, Rajasthan and Kashmir have shown that with increasing temperatures, COVID-19 cases have also increased in a statistically significant manner. A significant variability of temperature exists among the regions; however, temperature data that are representative of a whole region have been used in similar other correlation studies by various authors (Pirouz et al. 2020; Ujiie et al. 2020) .
    keywords: cases; covid-19; pandemic; regions; spread; temperature
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        item: #4217 of 7819
          id: cord-307497-wtfvoifb
      author: Abu-Raya, Bahaa
       title: Predictors of refractory Coronavirus disease (COVID-19) pneumonia
        date: 2020-04-09
       words: 512
      flesch: 16
     summary: In addition, refractory COVID-19 patients were more likely to receive oxygen, mechanical ventilation, expectorant, adjunctive treatment including corticosteroids, antiviral drugs and immune enhancers when compared to general COVID-19 patients. Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China An Easter outbreak of Salmonella Typhimurium DT 104A associated with traditional pork salami in Italy Burden of Children Hospitalized With Pertussis in Canada in the Acellular Pertussis Vaccine Era
    keywords: covid-19; refractory
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        item: #4218 of 7819
          id: cord-307502-vuju89lc
      author: Leipe, J.
       title: SARS-CoV-2 & Rheuma: Konsequenzen der SARS-CoV-2-Pandemie für Patienten mit entzündlich rheumatischen Erkrankungen. Ein Vergleich der Handlungsempfehlungen rheumatologischer Fachgesellschaften und Risikobewertung verschiedener antirheumatischer Therapien
        date: 2020-08-26
       words: 1866
      flesch: 32
     summary: Therapie kein Risiko für einen schweren Verlauf von COVID-19 bei Ob sich möglicherweise sogar günstige Effekte von Glukokortikoiden, bDMARDs und tsDMARDs auf den Verlauf von COVID-19 bei
    keywords: bei; cov-2; covid-19; der; dgrh; die; diseases; für; mit; patienten; patients; sars; und; update; von
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        item: #4219 of 7819
          id: cord-307512-70j4vn78
      author: Worku, Elliott
       title: Provision of ECPR during COVID-19: evidence, equity, and ethical dilemmas
        date: 2020-07-27
       words: 3968
      flesch: 29
     summary: Hypoxaemic respiratory failure leading to cardiac arrest appears to be common in COVID-19 patients. The most appropriate argument for withholding or withdrawing CCPR and ECPR in COVID-19 patients must be non-maleficence to the patient and others.
    keywords: arrest; cannulation; cardiac; covid-19; ecpr; hospital; pandemic; patients; resuscitation; support
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        item: #4220 of 7819
          id: cord-307516-5r5h1z1o
      author: Kahyaoglu Sut, Hatice
       title: Anxiety, depression, and related factors in pregnant women during the COVID‐19 pandemic in Turkey: A web‐based cross‐sectional study
        date: 2020-09-28
       words: 2224
      flesch: 44
     summary: key: cord-307516-5r5h1z1o authors: Kahyaoglu Sut, Hatice; Kucukkaya, Burcu title: Anxiety, depression, and related factors in pregnant women during the COVID‐19 pandemic in Turkey: This study aimed to assess the prevalence of anxiety and depression and related factors in pregnant women during the coronavirus disease 2019 (COVID‐19) pandemic.
    keywords: anxiety; covid-19; depression; pregnancy; women
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        item: #4221 of 7819
          id: cord-307520-8zmwh9ch
      author: Smith, L.E.
       title: Factors associated with adherence to self-isolation and lockdown measures in the UK: a cross-sectional survey
        date: 2020-09-06
       words: 4070
      flesch: 50
     summary: The Guardian Self-isolation compliance in the COVID-19 era influenced by compensation: findings from A recent survey in Israel Social, cognitive, and emotional predictors of adherence to physical distancing during the COVID-19 pandemic Predictors of non-adherence to public health instructions during the COVID-19 pandemic COVID-19 is rapidly changing: examining public perceptions and behaviors in response to this evolving pandemic Social norms motivate COVID-19 preventive behaviours Researching internet-based populations advantages and disadvantages of online survey research, online questionnaire authoring software packages, and web survey services How to survey citizens' compliance with COVID-19 public health measures? Statements included the perceived severity of COVID-19, perceived effectiveness of government measures, perceived likelihood of catching and spreading COVID-19, perceived costs of following government measures, fear of losing touch with friends and relatives, social pressure from friends and family to follow government measures, perceived legal consequences of not following government measures and positive consequences of the lockdown.
    keywords: adherence; covid-19; household; measures; symptoms
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        item: #4222 of 7819
          id: cord-307540-dr5m9pfk
      author: Coelho, Flávio C.
       title: Assessing the spread of COVID-19 in Brazil: Mobility, morbidity and social vulnerability
        date: 2020-09-18
       words: 3520
      flesch: 49
     summary: To identify regions with high geographical and social vulnerability, we proposed a classification scheme based on three main criteria: population mobility, socio-demographic-economic characteristics, and the available health care infrastructure in terms of hospital capacity. Number of COVID-19 cases notified per day was obtained from the site brasil.io/dataset/ covid19/casofull.
    keywords: areas; covid-19; micro; mobility; number; paulo; population; regions
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        item: #4223 of 7819
          id: cord-307546-g2oztc8j
      author: Brewer, Nikki
       title: Sonographer safety issues during the COVID-19 pandemic
        date: 2020-05-19
       words: 839
      flesch: 37
     summary: Sonographers should be tested for COVID-19 infection whenever they are exposed, as well. key: cord-307546-g2oztc8j authors: Brewer, Nikki; Huang, Gary; Kwon, Younghoon title: Sonographer safety issues during the COVID-19 pandemic date: 2020-05-19 journal: J Echocardiogr DOI: 10.1007/s12574-020-00474-w sha: doc_id: 307546 cord_uid: g2oztc8j nan We have read with great interest the article by Marriner et al., which provided important insights from a sonographer's standpoint into the processes of ensuring high-quality echocardiography [1] .
    keywords: covid-19; pandemic; sonographers
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        item: #4224 of 7819
          id: cord-307570-8f83k2ce
      author: Prodromos, Chadwick
       title: Hydroxychloroquine is effective, and consistently so used early, for Covid-19: A systematic review
        date: 2020-10-05
       words: 2766
      flesch: 42
     summary: We hypothesized that HCQ clinical studies would show significant efficacy more often 32 than not for COVID-19; and that efficacy would be greater if HCQ were used earlier in the course of the 33 disease. The third is that there are no unbiased studies showing a negative 86 effect of HCQ treatment of COVID-19.
    keywords: covid-19; hcq; hydroxychloroquine; patients; treatment
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        item: #4225 of 7819
          id: cord-307572-44503zbt
      author: Afolabi, Babalola I.
       title: Multimodality imaging of coronavirus disease 2019 (COVID-19): a pictorial essay
        date: 2020-07-30
       words: 1909
      flesch: 43
     summary: Consensus for prevention and management of coronavirus disease 2019 (COVID-19) for neurologists Chest radiographic and CT findings of the 2019 novel coronavirus disease (COVID-19): analysis of nine patients treated in Korea Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2 Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study An update on COVID-19 for the radiologist -a British Society of Thoracic Imaging statement COVID-19 | Radiology Reference Article | Radiopaedia.org Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review Chest radiographic and CT findings in novel swine-origin influenza A (H1N1) virus (S-OIV) infection Coronavirus disease 2019 (COVID-19): role of chest CT in diagnosis and management Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) Pneumonia Illustrated Brazilian consensus of terms and fundamental patterns in chest CT scans Temporal changes of CT findings in 90 patients with COVID-19 pneumonia: a longitudinal study Viral pneumonia imaging: practice essentials, radiography, computed tomography Findings of lung ultrasonography of novel corona virus pneumonia during the 2019-2020 epidemic COVID-19-associated acute hemorrhagic necrotizing encephalopathy: CT and MRI features Cerebrovascular accidents indicative of COVID-19 infection: about 4 observations in Guinea In COVID-19 patients, GGO is usually bilateral, multilobar, peripherally or posteriorly distributed (or both), and usually in the lower lobes.
    keywords: chest; coronavirus; covid-19; disease; patients
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        item: #4226 of 7819
          id: cord-307574-vmik4neu
      author: Ottaviani, S.
       title: Lung ultrasonography in patients with COVID-19: comparison with CT
        date: 2020-08-12
       words: 2550
      flesch: 41
     summary: Lung ultrasound and correlation with chest HRCT and clinical variables (Fig. 2) On comparing ultrasound and chest HRCT findings, excellent correlation was found between the ultrasound score for B-lines and classification (p<0.01) and percentage lung involvement on chest HRCT (r=0.935, p<0.001; Fig. 2 A recent study suggested that agreement between lung ultrasound and chest HRCT findings might vary depending on the severity of lung involvement, with diagnostic accuracy from 77% (mild involvement) to 93% (severe) (19) . WHO coronavirus disease dashboard Update of CT imaging features of 2019 novel coronavirus (2019-nCoV) Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia Point-of-care lung ultrasound in patients with COVID-19-a narrative review Application of lung ultrasound during the COVID-19 pandemic: a narrative review A brief review of lung ultrasonography in COVID-19: is it useful? Thoracic ultrasound and SARS-COVID-19: a pictorial essay Thoracic ultrasonography: a narrative review How I do it: lung ultrasound Lung B-line artefacts and their use Ultrasonography in lung pathologies: new perspectives Determination of a potential quantitative measure of the state of the lung using lung ultrasound spectroscopy Lung ultrasound for critically ill patients Bedside lung ultrasound in the assessment of alveolar-interstitial syndrome CT in detecting chest wall invasion by tumor: a prospective study COVID-19 pneumonia manifestations at the admission on chest ultrasound, radiographs, and CT: single-center study and comprehensive radiologic literature review A clinical study of noninvasive assessment of lung lesions in patients with coronavirus disease-19 (COVID-19) by bedside ultrasound Can lung ultrasound help critical care clinicians in the early diagnosis of novel coronavirus (COVID-19) pneumonia?
    keywords: chest; covid-19; hrct; lung; patients; ultrasound
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        item: #4227 of 7819
          id: cord-307585-dbc0spzv
      author: Klain, Michele
       title: Management of differentiated thyroid cancer through nuclear medicine facilities during Covid-19 emergency: the telemedicine challenge
        date: 2020-09-23
       words: 3479
      flesch: 35
     summary: It should be also taken into account that oncological patients have a higher risk of mechanical ventilation, intensive care unit admission, or death compared with patients without cancer Of note, thyroid cancer patients like any other oncological patient may suffer by impaired affective and cognitive functioning needing to physically interface to the doctor to feel reassured [18] .
    keywords: access; covid-19; pandemic; patients; rai; therapy; thyroid; tms; ward
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        item: #4228 of 7819
          id: cord-307610-tqvt5hzr
      author: Arora, Amarpreet Singh
       title: Current perspective of COVID-19 spread across South Korea: exploratory data analysis and containment of the pandemic
        date: 2020-08-08
       words: 3771
      flesch: 48
     summary: This paper includes the exploratory data analysis of COVID-19 cases in South Korea till July 8, 2020. This will also enable us to know how South Korea managed to flatten the curve of COVID-19 cases with time.
    keywords: cases; coronavirus; covid-19; korea; outbreak; south
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        item: #4229 of 7819
          id: cord-307622-r23eebet
      author: Kass, David A
       title: Obesity could shift severe COVID-19 disease to younger ages
        date: 2020-05-04
       words: 637
      flesch: 49
     summary: key: cord-307622-r23eebet authors: Kass, David A; Duggal, Priya; Cingolani, Oscar title: Obesity could shift severe COVID-19 disease to younger ages date: 2020-05-04 journal: Lancet DOI: 10.1016/s0140-6736(20)31024-2 sha: doc_id: 307622 cord_uid: r23eebet nan Obesity could shift severe COVID-19 disease to younger ages C o r o n a v Public messaging to younger adults, reducing the threshold for virus testing in obese individuals, and maintaining greater vigilance for this at-risk population should reduce the prevalence of severe COVID-19 disease.
    keywords: covid-19; obesity
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        item: #4230 of 7819
          id: cord-307623-8bd5m5tk
      author: Núñez Gil, Iván J.
       title: Health Outcome Predictive Evaluation for COVID 19 international registry (HOPE COVID-19), rationale and design
        date: 2020-09-23
       words: 1731
      flesch: 42
     summary: It will define a precise epidemiological profile of COVID-19 patients with higher severity and thus, admitted to a hospital. With an ambispective cohort design, eligible patients are those discharged, deceased or alive, from any hospital center with a confirmed diagnosis or a COVID-19 high suspicion.
    keywords: coronavirus; covid-19; patients
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        item: #4231 of 7819
          id: cord-307646-4m80o5yw
      author: Wu, Jianfeng
       title: Systemic corticosteroids and mortality in severe and critical COVID-19 patients in Wuhan, China
        date: 2020-09-03
       words: 3209
      flesch: 37
     summary: For severe COVID-19 patients at admission, corticosteroid use was not associated with improved or harmful outcome in either PSM or IPTW analysis. Compared to non-corticosteroid group, systemic corticosteroid use was not associated with beneficial effect in reducing in-hospital mortality in both severe cases (HR=1.77, 95% CI: 1.08-2.89, p=0.023), and critical cases (HR=2.07, 95% CI: 1.08-3.98, p=0.028).
    keywords: analysis; cases; corticosteroid; covid-19; mortality; patients; use
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        item: #4232 of 7819
          id: cord-307653-nyr6mtj1
      author: Palmeira, Patricia
       title: Why is SARS-CoV-2 infection milder among children?
        date: 2020-05-11
       words: 3461
      flesch: 22
     summary: The Facts During the Third Epidemic COVID-19 in posttransplant patients-report of 2 cases Clinical course of COVID-19 in a series of patients with chronic arthritis treated with immunosuppressive targeted therapies Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients Hypothesis for potential pathogenesis of SARS-CoV-2 infection-a review of immune changes in patients with viral pneumonia A systematic review of antibody mediated immunity to coronaviruses: antibody kinetics, correlates of protection, and association of antibody responses with severity of disease A pneumonia outbreak associated with a new coronavirus of probable bat origin Adaptive immune responses to primary and secondary dengue virus infections Antibodydependent enhancement of SARS coronavirus infection and its role in the pathogenesis of SARS Clinical features of patients infected with 2019 novel coronavirus in Wuhan Pathological findings of COVID-19 associated with acute respiratory distress syndrome Hemophagocytic lymphohistiocytosis: a rare diagnosis, an even rarer opportunity to appraise our understanding of the immune system Performance of current guidelines for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis Macrophage activation syndrome: A severe and frequent manifestation of acute pancreatitis in 362 childhood-onset compared to 1830 adult-onset systemic lupus erythematosus patients Development and initial validation of the MS score for diagnosis of macrophage activation syndrome in systemic juvenile idiopathic arthritis Refined characterization and reference values of the pediatric T-and B-cell compartments Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Non-specific effects of BCG vaccine on viral infections CD4 T-cell-mediated heterologous immunity between mycobacteria and poxviruses BCG Vaccination Enhances the Immunogenicity of Subsequent Influenza Vaccination in Healthy Volunteers: A Randomized, Placebo-Controlled Pilot Study Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of COVID-19 and Kawasaki Disease: Novel Virus and Novel Case Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study This is relevant because other clinical studies indicate that COVID-19 patients have lymphocytopenia with high levels of several cytokines and chemokines, such as G-CSF, IP-10, MCP-1, MIP-1a, and TNF-a (48, 49) .
    keywords: ace2; angiotensin; children; cov-2; covid-19; disease; infection; patients; sars
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        item: #4233 of 7819
          id: cord-307660-onz6vfre
      author: Titanji, Boghuma K
       title: Use of Baricitinib in Patients with Moderate and Severe COVID-19
        date: 2020-06-29
       words: 1088
      flesch: 36
     summary: Coronavirus Disease 2019 -Situation report number 148 COVID-19: consider cytokine storm syndromes and immunosuppression Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Baricitinib as potential treatment for 2019-nCoV acute respiratory disease COVID-19: combining antiviral and anti-inflammatory treatments Baricitinib therapy in COVID-19: A pilot study on safety and clinical impact Mechanism of baricitinib supports artificial intelligence-predicted testing in COVID-19 patients IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes Estimates of the severity of coronavirus disease 2019: a model-based analysis Baricitinib for the treatment of rheumatoid arthritis and systemic lupus erythematosus: a 2019 update THU0211 Meta-analysis of serious infections with baricitinib, tofacitinib and biologic dmards in rheumatoid arthritis In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vincent Marconi and Raymond F Schinazi are partially funded by -Emory University Center for AIDS Research (AI050409). Severe COVID-19 patients met any of the following criteria; respiratory rate (RR) >30 times/min, oxygen saturation by pulse oximetry 93% at rest or PaO2/FiO2<300 mmHg.
    keywords: baricitinib; covid-19; disease; patients
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        item: #4234 of 7819
          id: cord-307671-f9l2l8fi
      author: Said, Mohammed
       title: The Forgotten Element in the Resumption of Elective Bariatric Surgery During the COVID-19 Pandemic: the Patient Consent!
        date: 2020-09-19
       words: 2201
      flesch: 35
     summary: These recommendations included a risk-stratified triaging system to prioritize tiers of bariatric patients. This study presents a survey of 266 bariatric candidates who were rescheduled for bariatric surgery after postponement during the COVID-19 pandemic.
    keywords: covid-19; infection; pandemic; surgery
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        item: #4235 of 7819
          id: cord-307673-ekajojon
      author: Kaukinen, Catherine
       title: When Stay-at-Home Orders Leave Victims Unsafe at Home: Exploring the Risk and Consequences of Intimate Partner Violence during the COVID-19 Pandemic
        date: 2020-06-06
       words: 6134
      flesch: 39
     summary: Mazza, Maranoa, Laib, Janiria, and Sania (2020) have suggested that COVID-19 stay-at-home orders and social distancing will likely lead to a woman's home becoming one of the most dangerous places for IPV victims due in large part to the requirement to quarantine day-after-day with their violent and abusive partner with limited access to those that might provide care and assistance. In looking at the way in which the COVID-19 pandemic is likely to shape the incidence, prevalence, and impact of IPV it is important to note that scholars have explored how past natural disasters and epidemics have shaped trends in rates of violence, impacted the health and well-being of IPV victims, but also exacerbated the factors associated with violent behaviors and victimization.
    keywords: covid-19; home; ipv; pandemic; partner; police; risk; victims; violence; women
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        item: #4236 of 7819
          id: cord-307688-r1pgmn6i
      author: Goenka, Mahesh K.
       title: Impact of COVID-19 on gastrointestinal endoscopy practice in India: a cross-sectional study
        date: 2020-06-18
       words: 3066
      flesch: 40
     summary: The major reasons for the decrease in endoscopy procedures during the COVID-19 pandemic were fewer patients coming to the hospital due to government-mandated national lock-down (227 responses), endoscopists themselves limiting the number of procedures due to the latest guideline recommendations for avoiding routine endoscopies (324 responses), limiting contact with patients due to the fear of getting exposed (127 responses), difficulty in managing usual patient volumes due to reduced availability of staff due to lockdown (57 responses), and in at least one-third (108 responses), reduction in endoscopic procedures was due to advice from hospital management to avoid routine endoscopy procedures, which were in a stand-by mode for the potential surge and hence were limiting any elective procedures. The daily average number of endoscopy procedures done in 2019 by the participants in their respective units varied from < 10 for 23.4 %, to 10 to 25 for 35.8 %, 26 to 50 for 23.1 %, 51 to 100 for 8.3 %, and more than 100 for 9.4 % of respondents (▶ Fig. 1 ).
    keywords: covid-19; endoscopists; endoscopy; practice; procedures
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        item: #4237 of 7819
          id: cord-307690-1qqyixun
      author: Preti, Emanuele
       title: Personality Disorders in Time of Pandemic
        date: 2020-11-10
       words: 5276
      flesch: 28
     summary: Trends Psychiatry Psychother Psychological and behavioural responses to coronavirus disease 2019: the role of personality Cognitive therapy of personality disorders Specific types of personality disorders Cognitive and brain function in schizotypal personality disorder Schizotypal personality disorder: a current review Neurophysiological evidence of impaired self-monitoring in schizotypal personality disorder and its reversal by dopaminergic antagonism The Oxford-Liverpool Inventory of Feelings and Experiences (O-LIFE): further description and extended norms Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring Personality disorders in homeless drop-in center clients Study of the influence of mental disorders on the problems of social rehabilitation Schizoid personality traits among the homeless mentally III: a quantitative and qualitative report Personality disorders and treatment drop out in the homeless Borderline personality disorder: hypothalamus pituitary adrenal axis and findings from neuroimaging studies Neural correlates of emotional action control in anger-prone women with borderline personality disorder Relationship between personality dimensions and psychological well-being among university students during pandemic lockdown Comparison of attachment styles in borderline personality disorder and obsessive-compulsive personality disorder Cluster B personality traits and attachment Reviewing the clinical significance of 'fear of abandonment' in borderline personality disorder Trust and rejection sensitivity in personality disorders Postdisaster course of alcohol use disorders in systematically studied survivors of 10 disasters Tobacco use after experiencing a major natural disaster: analysis of a longitudinal study of 2063 young adults Consumption of cigarettes, alcohol, and marijuana among New York City residents six months after the September 11 terrorist attacks Suicidal thoughts and behaviors and social isolation: a narrative review of the literature Heightened sensitivity to facial expressions of emotion in borderline personality disorder Affective temperament, attachment style, and the psychological impact of the COVID-19 outbreak: an early report on the Italian general population Temperament traits and personality disorders. Predictors for personality disorders Depression in histrionic personality disorder Exploring the structure of narcissism: toward an integrated solution The narcissism spectrum model: a synthetic view of narcissistic personality Initial construction and validation of the Pathological Narcissism Inventory Narcissistic subtypes and contingent self-esteem: do all narcissists base their self-esteem on the same domains? Grandiose and entitled, but still fragile: a network analysis of pathological narcissistic traits Abdelrahman M Personality traits, risk perception, and protective behaviors of Arab residents of Qatar during the COVID-19 pandemic Pathological narcissism and narcissistic personality disorder Factorial structure of traits delineating personality disorders in clinical and general population samples Coronavirus (COVID-19) in the United Kingdom: a personality-based perspective on concerns and intention to self-isolate Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and metaanalysis with comparison to the COVID-19 pandemic Obsessive-compulsive personality disorder and component personality traits Intolerance of uncertainty and obsessivecompulsive personality disorder Relationship between hypochondriasis and obsessivecompulsive personality disorder: close relatives separated by nosological schemes?
    keywords: cluster; covid-19; disorders; measures; mitigation; pandemic; patients; pds; personality; traits
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        item: #4238 of 7819
          id: cord-307691-oufc6ywp
      author: Li, Runmin
       title: Efficacy and safety of Shufeng Jiedu capsule for coronavirus disease 2019 (COVID-19): A protocol for systematic review and meta-analysis
        date: 2020-08-07
       words: 1688
      flesch: 44
     summary: Available at A GRADE Working Group approach for rating the quality of treatment effect estimates from network meta-analysis Value analysis of Chinese medicine Shufeng Jiedu capsule combined with Abidor in the treatment of mild COVID-19 key: cord-307691-oufc6ywp authors: Li, Runmin; Li, Ying; Li, Bingchen; Sun, Haiyang; Liu, Xinyu; Ge, Xin; Liu, Yuanxiang; Yang, Jiguo title: Efficacy and safety of Shufeng Jiedu capsule for coronavirus disease 2019 (COVID-19): A protocol for systematic review and meta-analysis date: 2020-08-07 journal: Medicine (Baltimore) DOI: 10.1097/md.0000000000021615 sha: doc_id: 307691 cord_uid: oufc6ywp BACKGROUND: From the end of 2019 to the present, coronavirus disease 2019 (COVID-19) has put considerable pressure on the worlds medical system and caused significant mortality and economic losses around the world.
    keywords: capsule; covid-19; disease; jiedu; shufeng; treatment
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        item: #4239 of 7819
          id: cord-307702-n74wvika
      author: Durant, Thomas J S
       title: Impact of COVID-19 Pandemic on Laboratory Utilization
        date: 2020-07-14
       words: 2818
      flesch: 35
     summary: We performed a retrospective assessment of laboratory test order and specimen container utilization at a single, urban tertiary care medical center. We performed a retrospective assessment of laboratory test order and specimen container utilization at a single, urban tertiary care medical center.
    keywords: covid-19; laboratory; pandemic; pcr; testing; tests; utilization; volume
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        item: #4240 of 7819
          id: cord-307710-dlpfbnb1
      author: Neradi, Deepak
       title: Management of Orthopaedic Patients During COVID-19 Pandemic in India: A Guide
        date: 2020-04-27
       words: 1582
      flesch: 53
     summary: These patients should be managed as COVID positive patients and strict precautions should be taken to avoid transmission to caregivers or to other patients. Ensure that the healthcare staff including the doctor, nurses and paramedical staff have no signs and symptoms related to COVID-19 infection or any contact with COVID patients in the past 14 days and it is better to screen the health care staff, if feasible.
    keywords: care; covid-19; health; india; patients
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        item: #4241 of 7819
          id: cord-307741-j6ihxzm2
      author: Wang, Cuiyan
       title: A Longitudinal Study on the Mental Health of General Population during the COVID-19 Epidemic in China
        date: 2020-04-13
       words: 3463
      flesch: 40
     summary: Subsequently, rapid surge in the number of COVID-19 cases was observed during March 2020 in Iran, Italy, South Korea, Europe and United States. The important unexpected finding of our study is the stable levels of stress, anxiety and depression despite sharp increases in the number of COVID-19 cases between the two surveys as well as statistically but not clinically significant reduction in the psychological impact on the general population.
    keywords: anxiety; covid-19; depression; health; ies; respondents; scores; survey
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        item: #4242 of 7819
          id: cord-307745-8dq3vyw9
      author: Rossi, Rosario
       title: PROTECTIVE ROLE OF CHRONIC TREATMENT WITH DIRECT ORAL ANTICOAGULANTS IN ELDERLY PATIENTS AFFECTED BY INTERSTITIAL PNEUMONIA IN COVID-19 ERA
        date: 2020-06-06
       words: 946
      flesch: 40
     summary: [1] . Elderly patients affected by chronic heart disease showed a high mortality risk in the setting of COVID-19 interstitial pneumonia Further studies on a larger population of patients, possibly randomized, are needed to confirm the protective role of DOAC in reducing the mortality risk in COVID-19 patients with pre-existing cardiac diseases.
    keywords: covid-19; disease; patients
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        item: #4243 of 7819
          id: cord-307751-4r44ww59
      author: Tran, Bach Xuan
       title: Characterize health and economic vulnerabilities of workers to control the emergence of COVID-19 in an industrial zone in Vietnam
        date: 2020-05-12
       words: 1966
      flesch: 31
     summary: key: cord-307751-4r44ww59 authors: Tran, Bach Xuan; Vu, Giang Thu; Latkin, Carl A.; Pham, Hai Quang; Phan, Hai Thanh; Le, Huong Thi; Ho, Roger C.M. title: Characterize health and economic vulnerabilities of workers to control the emergence of COVID-19 in an industrial zone in Vietnam date: 2020-05-12 journal: Saf Sci DOI: 10.1016/j.ssci.2020.104811 sha: doc_id: 307751 cord_uid: 4r44ww59 The detection of first COVID-19 infected industrial worker in Vietnam on 13 April 2020 prompted timely effort to examine the health problems, behaviors, and health services access of industrial workers to inform effective and appropriate COVID-19 control measures, minimizing the risk of industrial sites becoming the next disease cluster. For evidence on health problems, behaviors, and healthcare access of industrial workers in Vietnam, we conducted a review of relevant literature.
    keywords: covid-19; health; industrial; vietnam; workers
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        item: #4244 of 7819
          id: cord-307761-luzs56k5
      author: Scarmozzino, Federico
       title: Covid-19 and the Subsequent Lockdown Modified Dietary Habits of Almost Half the Population in an Italian Sample
        date: 2020-05-25
       words: 3007
      flesch: 46
     summary: Related to this, 36.8% of responders reported a decrease in alcohol consumption, even though 10.1% of them reported an increase. Related to this, 36.8% of responders reported a decrease in alcohol consumption ( Figure 2C ), even though 10.1% of them reported an increase.
    keywords: consumption; diet; figure; food; health; lockdown; responders
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        item: #4245 of 7819
          id: cord-307791-59ja1ith
      author: Pranata, Raymond
       title: Body Mass Index and Outcome in Patients with COVID-19: A Dose-Response Meta-Analysis
        date: 2020-07-29
       words: 3871
      flesch: 41
     summary: The sensitivity analysis was performed by excluding studies with a BMI cut-off other than >30 kg/m 2 for obesity analysis. Patients with severe obesity and full expression of the obstructive sleep apnea phenotype receive less benefit from non-invasive positive pressure ventilation, and require medical management of its comorbid conditions.
    keywords: analysis; bmi; covid-19; meta; mortality; obesity; outcome; patients
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        item: #4246 of 7819
          id: cord-307804-s94mdu3h
      author: Mady, Ossama M.
       title: Increased incidence of otitis externa in covid-19 patients
        date: 2020-08-11
       words: 548
      flesch: 40
     summary: Increased incidence of otitis externa in COVID-19 patients (18% of study group) and symptoms starting mainly between the 5th to 8th day of COVID-19 infection. Increased incidence of otitis externa in COVID-19 patients (18% of study group) and symptoms starting mainly between the 5 th to 8 th day of COVID-19 patients with otitis externa were not complaining of anosmia (5% of all study group complaining of otitis externa without anosmia).
    keywords: externa; otitis
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        item: #4247 of 7819
          id: cord-307857-1xj0ys7c
      author: Headey, Derek
       title: Impacts of COVID-19 on childhood malnutrition and nutrition-related mortality
        date: 2020-07-27
       words: 1229
      flesch: 39
     summary: Our projections emphasise the crucial need for the actions to protect child nutrition that are urged by the UN leaders in the accompanying Comment. Of particular concern is an expected increase in child malnutrition, including wasting, due to steep declines in household incomes, changes in the availability and affordability of nutritious foods, and interruptions to health, nutrition, and social protection services.
    keywords: child; covid-19; health; nutrition
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        item: #4248 of 7819
          id: cord-307862-a082sghm
      author: ten Cate, Hugo
       title: Thrombosis management in times of COVID-19 epidemy; a Dutch perspective
        date: 2020-04-20
       words: 1231
      flesch: 34
     summary: While normally, a Wells rule or similar algorithm will be applied to work up such patients (and ECG recording of course) with a d-dimer test in case of a low suspicion for PE, the threat is that in the present situation this part of the diagnostic pathway is forgotten. [1] has caused major shifts in healthcare organization, towards far more and acute attention for patients suspected from COVID-19 infection at the potential cost of less attention for regular care.
    keywords: covid-19; infection; patients
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        item: #4249 of 7819
          id: cord-307868-bsmni8sh
      author: Dhungana, Nimesh
       title: Human dignity and cross-border migrants in the era of the COVID-19 pandemic
        date: 2020-08-28
       words: 2674
      flesch: 35
     summary: The paper tentatively concludes that the Nepali government's decision to seal its border with India, and its subsequent interventions to curtail the flow of outbreak, have undermined the human dignity of Nepali migrants. The above accounts do not mean that Nepali migrants have passively accepted how they are being treated.
    keywords: border; covid-19; dignity; human; migrants; nepal; rights
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        item: #4250 of 7819
          id: cord-307880-atrihlc2
      author: Jhaveri, Kinnari
       title: “Soup cans, brooms, and Zoom:” Rapid conversion of a cancer survivorship program to telehealth during COVID‐19
        date: 2020-07-16
       words: 1237
      flesch: 35
     summary: In the context of COVID-19, challenges faced by cancer survivors have intensified. In a rapid response to the needs of cancer survivors during COVID-19, the SWGP transitioned to telehealth and adapted content, increased accessibility and expanded the reach of the program while maintaining the quality of the intervention and its foundation in evidenced-This article is protected by copyright.
    keywords: cancer; covid-19; survivors; telehealth
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        item: #4251 of 7819
          id: cord-307927-bwltiaeo
      author: Amiel, Gilad E.
       title: Caring for the Caregivers: Mental and Spiritual Support for Healthcare Teams During the COVID-19 Pandemic and Beyond
        date: 2020-09-15
       words: 948
      flesch: 46
     summary: Healthcare teams are adjusting to an ever-changing environment with an elusive disease that requires adaptation to new practices. This is only one example of a variety of initiatives that hospitals should take to proactively support healthcare teams in these challenging times.
    keywords: covid-19; healthcare; support
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        item: #4252 of 7819
          id: cord-307929-286i4rue
      author: Bustati, Nour
       title: The Impact Of COVID-19 Pandemic on Patients Receiving Orthodontic Treatment- An Online Questionnaire Cross Sectional Study
        date: 2020-10-23
       words: 3147
      flesch: 46
     summary: An Online Questionnaire Cross Sectional Study date: 2020-10-23 journal: J World Fed Orthod DOI: 10.1016/j.ejwf.2020.10.003 sha: doc_id: 307929 cord_uid: 286i4rue Background The spread of COVID-19 has led to a major public health issue; most dental clinics were closed and millions of orthodontic patients were unable to complete their treatment, this study aimed to assess the challenges faced by patients receiving orthodontic treatment and their proffered solutions to overcoming these challenges during this pandemic. On the other hand, patients receiving orthodontics treatment require multiple checkup visits to their orthodontist to adjust their appliances over a long-lasting process which sometimes may take up to more than 2 years, therefore millions of orthodontic patients weren't able to receive the care they needed when this pandemic and the closing of clinics that followed took place [8] .
    keywords: covid-19; pandemic; patients; treatment
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        item: #4253 of 7819
          id: cord-307941-kato4ix2
      author: Ameri, Arefeh
       title: Tele-Pharmacy: A New Opportunity for Consultation in COVID-19 Pandemic
        date: 2020-06-14
       words: 730
      flesch: 40
     summary: Tele-pharmacy is one of the practical aspects of telemedicine that refers to providing pharmaceutical services within the scope of a pharmacist's responsibilities, with a temporal and spatial distance between patients as the consumers of health services, and healthcare providers. As a result, it can reduce the costs for patients and health care providers.
    keywords: covid-19; health; tele
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        item: #4254 of 7819
          id: cord-307945-wkz43axo
      author: Baud, Grégory
       title: Endocrine surgery during and after the Covid-19 epidemic: Expert guidelines in France
        date: 2020-04-30
       words: 2086
      flesch: 26
     summary: Non-suspect goiters responsible for severe compressive symptoms (inspiratory dyspnea due to tracheal compression, dysphagia due to esophageal compression, superior vena cava syndrome due to deep vein compression) must also be scheduled for semi-urgent surgery before the epidemic ends. Four scheduling levels were defined to help prioritize patients (these levels may change according to how the epidemic setting evolves): Urgent surgery that must be carried out as soon as possible because even a short deferral would be life-threatening.
    keywords: covid-19; epidemic; patients; surgery; thyroid; treatment
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        item: #4255 of 7819
          id: cord-307983-gjdza9bh
      author: Hawdon, James
       title: Cybercrime in America amid COVID-19: the Initial Results from a Natural Experiment
        date: 2020-06-10
       words: 6049
      flesch: 38
     summary: Fortune Crime rates plummet around the world as the coronavirus keeps people inside Phishing for suitable targets in the Netherlands: Routine activity theory and phishing victimization Applying routine activity theory to cybercrime: A theoretical and empirical analysis The accuracy of measurements with probability and nonprobability survey samples: Replication and extension Identifying potential factors of adolescent online victimization for high school seniors Adolescent online victimization: A test of routine activities theory Potential factors of online victimization of youth: With this modification in mind, online routine activities can increase the likelihood of victimization by bringing potential targets into virtual contact with offenders in environments lacking guardians (see Eck & Clarke, 2003; Reyns et al., 2011) .
    keywords: activities; covid-19; cybervictimization; increase; online; pandemic; post; routine; sample; target; victimization
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        item: #4256 of 7819
          id: cord-307998-uaubbz4r
      author: Ben Abdallah, Iannis
       title: Early experience in Paris with the impact of the COVID-19 pandemic on vascular surgery
        date: 2020-04-23
       words: 395
      flesch: 47
     summary: Regarding staff management, our daily rotations have been completely modified with one team 4 dedicated to vascular emergencies in each center. According to the French Society for Vascular Surgery's 6 recommendations based on the 3Ss principle (save Staff, Space and Stuff), our surgical activity is 7 now limited to the following emergencies: acute aortic syndromes, critical and acute limb 8 ischemia, symptomatic carotid stenosis, mesenteric ischemia and vascular access for 9 hemodialysis, with endovascular favored over open repair whenever possible to shorten hospital 10 and ICU stay.
    keywords: covid-19; icu
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        item: #4257 of 7819
          id: cord-308010-ix0xi5jb
      author: Mcloughlin, Benjamin C.
       title: Functional and cognitive outcomes after COVID-19 delirium
        date: 2020-07-14
       words: 2273
      flesch: 41
     summary: To ascertain delirium prevalence and outcomes in COVID-19. Nonetheless, our data are strengthened by the consistent and systematic approach to delirium detection and robust methods for follow-up.
    keywords: covid-19; delirium; mortality; outcomes; patients
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        item: #4258 of 7819
          id: cord-308018-qao9wxzq
      author: Tisdell, Clement A.
       title: Economic, social and political issues raised by the COVID-19 pandemic
        date: 2020-08-20
       words: 8270
      flesch: 51
     summary: Probably, it is not only those who rely on work for their survival who support these policies but also a group of capitalists and investors who are concerned about the falling return on their investments as a result of reduced economic activity. Determining appropriate economic policies to respond to the outbreak and human-to-human spread of COVID-19 has proven to be extremely challenging because major measures to stem the level of infections and death rates from the disease involve a high economic cost in terms of the levels of income and economic production forgone.
    keywords: covid-19; death; disease; groups; hospital; incidence; individuals; number; pandemic; patients; restrictions
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        item: #4259 of 7819
          id: cord-308069-iydjrmhh
      author: Contreras, Sebastián
       title: Statistically-based methodology for revealing real contagion trends and correcting delay-induced errors in the assessment of COVID-19 pandemic
        date: 2020-07-03
       words: 4975
      flesch: 37
     summary: From this plot, we can assess both successful and unfortunate effects that the different governmental actions have had on the spreading dynamics of COVID-19 in Chile, and specifically in Santiago, by analyzing corrected R t trends and comparing them with daily reported cases. Different methods for diagnosing COVID-19 have been developed and reported in the literature, with real-time RT-PCR being the standard applied globally (Lippi et al., 2020) .
    keywords: cases; covid-19; data; days; et al; testing; time
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        item: #4260 of 7819
          id: cord-308075-1ftswsm8
      author: Segura, Patricia Sanz
       title: Involvement of the digestive system in COVID-19. A review
        date: 2020-10-09
       words: 4834
      flesch: 36
     summary: Epub ahead of print Air surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection First case of 2019 novel coronavirus in the United States Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: A descriptive, cross-sectional multicenter study Prevalence and characteristics of gastrointestinal symptoms in patients with SARS-CoV-2 infection in the United States: A multicenter cohort study. In the latest update, of 12 May 2020, the controlled cohort was 491 patients; up to that date, notably, there was a 36% mortality rate in patients with cirrhosis ----much higher than the mortality rate in other patients with non-cirrhosis chronic liver disease (7%) and that in patients with a liver transplant (20%).
    keywords: cases; covid-19; disease; endoscopy; infection; liver; patients; risk; sars; studies; symptoms
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        item: #4261 of 7819
          id: cord-308080-1heu9vuv
      author: Simulundu, Edgar
       title: First COVID-19 Case in Zambia – Comparative phylogenomic analyses of SARS-CoV-2 detected in African countries
        date: 2020-10-06
       words: 1714
      flesch: 40
     summary: Ethical review and approval to publish: Ethical approval for case study and phylogenomic sequencing, and publication of this case study was obtained from the University of Zambia positive only in the case under study. Whilst African countries were relatively spared initially, the initial low incidence of COVID-19 cases was not sustained for long due to continuing travel links between China, Europe and Africa..
    keywords: africa; case; cov-2; covid-19; sars; zambia
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        item: #4262 of 7819
          id: cord-308085-x00c3eex
      author: Kirsch, David G.
       title: Lack of supporting data make the risks of a clinical trial of radiation therapy as a treatment for COVID-19 pneumonia unacceptable
        date: 2020-05-12
       words: 2280
      flesch: 46
     summary: Taken together, these preclinical data are insufficient to support a clinical trial of low dose radiation therapy in patients with COVID-19. 12 Covid-19: four fifths of cases are asymptomatic, China figures indicate Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship Universal Screening for SARS-CoV-2 in Women Admitted for Delivery Clinical Characteristics of Coronavirus Disease 2019 in China Characteristics of Hospitalized Adults With COVID-19 in an Integrated Health Care System in California Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region Covid-19 in Critically Ill Patients in the Seattle Region -Case Series Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the Is low dose radiation therapy a potential treatment for COVID-19 pneumonia?
    keywords: covid-19; patients; pneumonia; radiation; therapy
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        item: #4263 of 7819
          id: cord-308100-tvk47fd7
      author: Soetikno, Roy
       title: Considerations in performing endoscopy during the COVID-19 pandemic
        date: 2020-03-27
       words: 2712
      flesch: 51
     summary: Additional care must be instituted when handling blood samples or specimens because the virus has been detected in the blood of COVID-19 patients. Science Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan Suggestions of Infection Prevention and Control in Digestive Endoscopy During Current 2019-nCoV Pneumonia Outbreak in Wuhan COVID-19) outbreak: what the department of endoscopy should know Recommendations for the prevention of transmission of SARS during GI endoscopy Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study.
    keywords: covid-19; endoscopy; infection; patients; ppe; sars; use
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        item: #4264 of 7819
          id: cord-308114-68cgub5o
      author: Afrin, Lawrence B.
       title: Covid-19 Hyperinflammation and Post-Covid-19 Illness May Be Rooted in Mast Cell Activation Syndrome
        date: 2020-09-10
       words: 3459
      flesch: 25
     summary: r o o f summarize the evidence suggesting that mast cell activation disease, the majority of which is constituted by the prevalent, but only recently recognized, mast cell activation syndrome (MCAS), fits very well with these enigmatic findings. J o u r n a l P r e -p r o o f Mast cell-orchestrated immunity to pathogens A concise, practical guide to diagnostic assessment for mast cell activation disease Mast cell activation disease: An underappreciated cause of neurologic and psychiatric symptoms and diseases Often seen, rarely recognized: mast cell activation disease -a guide to diagnosis and therapeutic options Mast cell activation disease and the modern epidemic of chronic inflammatory disease Mast Cell Regulatory Gene Variants Are Common in Mast Cell Activation Syndrome Characterization of Mast Cell Activation Syndrome Diagnosis of mast cell activation syndrome: a global consensus-2 The biology of Kit in disease and the application of pharmacogenetics The association between obesity and poor outcome after COVID-19 indicates a potential therapeutic role for montelukast Mutational profiling in the peripheral blood leukocytes of patients with systemic mast cell activation syndrome using next-generation sequencing Covid-19 in Critically Ill Patients in the Seattle Region -Case Series Epidemiology of COVID-19 Clinical characteristics of 113 deceased patients with coronavirus disease 2019:
    keywords: covid-19; et al; infection; mast; mcas; patients
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        item: #4265 of 7819
          id: cord-308116-it0alwps
      author: Algara, M.
       title: Low dose anti-inflammatory radiotherapy for the treatment of pneumonia by covid-19: A proposal for a multi-centric prospective trial
        date: 2020-06-15
       words: 4088
      flesch: 36
     summary: Secondary objectives will include the safety of bilateral lung LD-RT, an improvement in the radiology image, overall mortality rates at 15 and 30 days after irradiation and characterizing anti-inflammatory mechanisms of LD-RT by measuring the level of expression of adhesion molecules, anti-inflammatory cytokines and oxidative stress mediators. As well as promoting the induction of macrophage and polymorphonuclear apoptosis low-dose irradiation also lowers the levels of NO, iNOS, L and E selectins, ROS, TNF-a or IL-beta 1 secretion together with an increase in production and expression of anti-inflammatory cytokines, such as anti-inflammatory cytokine TGF-b1 and of apoptosis mediators such as NF-jB. This anti-inflammatory effect of LD-RT was greatest at 48 h after irradiation and was lost after 72 h
    keywords: covid-19; dose; irradiation; patients; pneumonia; study; treatment
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        item: #4266 of 7819
          id: cord-308123-eu0azqfu
      author: Lee, Yun Young
       title: Long-acting nanoparticulate DNase-1 for effective suppression of SARS-CoV-2-mediated neutrophil activities and cytokine storm
        date: 2020-10-23
       words: 5029
      flesch: 47
     summary: To further support the acting of long acting DNase-1 on the lungs, we evaluated the biodistribution of nanoparticulate DNase-1 (Fig. S5) . Differences were also observed for DNase-1 levels among the groups.
    keywords: acting; cov-2; covid-19; dnase-1; fig; levels; neutrophil; patients; sars; sepsis; treatment
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        item: #4267 of 7819
          id: cord-308155-696bhy9v
      author: TRECARICHI, E. M.
       title: Characteristics, outcome and predictors of in-hospital mortality in an elderly population from a SARS-CoV-2 outbreak in a long-term care facility.
        date: 2020-07-02
       words: 2979
      flesch: 46
     summary: We conducted a retrospective, observational cohort study to assess clinical characteristics and baseline predictors of mortality of COVID-19 patients hospitalized after an outbreak of SARS-CoV-2 infection in a LTCF. To the best of our knowledge, hypernatremia has been never recognized as independent risk factor for mortality in COVID-19 patients.
    keywords: covid-19; medrxiv; mortality; patients; perpetuity; preprint
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        item: #4268 of 7819
          id: cord-308159-qqxsrp87
      author: Elder, Colby
       title: Expectant management of pneumothorax in intubated COVID-19 positive patients: a case series
        date: 2020-09-21
       words: 2077
      flesch: 46
     summary: We present four cases of pneumothorax in COVID-19 positive patients who were managed without chest tube placement despite being on positive pressure ventilation. Historically, a small pneumothorax has been shown to be successfully treated without chest tube insertion, but this management has yet to be proven in COVID-19 pneumonia patients.
    keywords: chest; covid-19; hospital; patient; pneumothorax
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        item: #4269 of 7819
          id: cord-308165-pk8d48hs
      author: Olu, Olushayo Oluseun
       title: Moving from rhetoric to action: how Africa can use scientific evidence to halt the COVID-19 pandemic
        date: 2020-10-28
       words: 3719
      flesch: 34
     summary: In this article, we review the relevant scientific literatures on the COVID-19 pandemic, and synthesize the relevant evidence that could potentially change the game in Africa's fight against the disease; finally we propose strategic recommendations for prevention and control of COVID-19 transmission in the Africa continent specifically. WHO recommends that all laboratory confirmed cases should be isolated and managed in health facility settings but where this is not possible priority should be given to cases with the probability of poor outcomes such as those aged above 60 years and with underlying medical conditions which put them at higher risk [35] . Recommendations for COVID-19 strategy development specific for the Africa continent Putting the above scientific evidences on the characteristics and dynamics of COVID-19 transmission, prevention and control into perspective against the backdrop of the social, cultural and economic context in Africa, we deduce several lessons which could guide African countries to better prepare for and respond to the COVID-19 pandemic on the continent.
    keywords: african; control; countries; covid-19; disease; health; prevention; transmission; virus
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        item: #4270 of 7819
          id: cord-308168-kte6btc6
      author: Procianoy, Renato Soibelmann
       title: Neonatal COVID-19: little evidence and the need for more information
        date: 2020-04-11
       words: 1756
      flesch: 30
     summary: More definite evidence is needed Coronavirus disease 2019 (COVID-19) and pregnancy: what obstetricians need to know Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China A case report of neonatal COVID-19 infection in China Clinical and CT features in pediatric patients with COVID-19 infection: different points from adults First case of neonate infected with novel coronavirus pneumonia in China COVID-19 guidance for maternity services statewide maternity and neonatal clinical network American College of Obstetrics and Gynecologists Protecting healthcare workers from SARS-CoV-2 infection: practical indications Influenza aerosols in UK hospitals during the H1N1 (2009) pandemic ---the risk of aerosol generation during medical procedures Aerosol-generating procedures and risk of transmission of acute respiratory infections: a systematic review Infection prevention and control of epidemic-and pandemic-prone acute respiratory infections in health care Non-invasive mechanical ventilation: models to assess air and particle dispersion Exhaled air dispersion and removal is influenced by isolation room size and ventilation settings during oxygen delivery via nasal cannula Evaluation of droplet dispersion during non-invasive ventilation, oxygen therapy, nebuliser treatment and chest physiotherapy in clinical practice: implications for management of pandemic influenza and other airborne infections Mechanical ventilation and bronchopulmonary dysplasia What's known about neonatal COVID-19 infection?
    keywords: care; cases; covid-19; infection; neonatal
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        item: #4271 of 7819
          id: cord-308184-w8ewm8ve
      author: Sarzi-Puttini, Piercarlo
       title: How to handle patients with autoimmune rheumatic and inflammatory bowel diseases in the COVID-19 era: An expert opinion
        date: 2020-05-05
       words: 3437
      flesch: 32
     summary: Although the available data do not suggest that there is a specific risk of SARS-CoV-2 infection and morbidity in IBD patients receiving immunosuppressive treatment, it is known that opportunistic infections have deleterious effects on such patients, which suggests that the risks and benefits of the treatment should be balanced before continuing its administration. However, to the best of our knowledge, the only data concerning the risk of SARS-CoV-2 infection in IBD patients come from just one study [19] , and there are no data concerning the risk in rheumatic patients.
    keywords: covid-19; diseases; drugs; ibd; infection; patients; risk; treatment
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        item: #4272 of 7819
          id: cord-308195-nlibv0u4
      author: Arleo, T. L.
       title: Clinical Course and Outcomes of coronavirus disease 2019 (COVID-19) in Rheumatic Disease Patients on Immunosuppression: A case Cohort Study at a Single Center with a Significantly Diverse Population
        date: 2020-10-27
       words: 3588
      flesch: 40
     summary: In hospitalized rheumatic disease patients, one potential confounder is that rheumatic disease patients admitted to the hospital experience poor outcomes regardless of COVID-19 infection key: cord-308195-nlibv0u4 authors: Arleo, T. L.; Tong, D. C.; Shabto, J. M.; O'Keefe, G. D.; Khosroshahi, A. title: Clinical Course and Outcomes of coronavirus disease 2019 (COVID-19) in Rheumatic Disease Patients on Immunosuppression: A case Cohort Study at a Single Center with a Significantly Diverse Population date: 2020-10-27 journal: nan DOI: 10.1101/2020.10.26.20219154 sha: doc_id: 308195 cord_uid: nlibv0u4 Objectives To determine clinical course and outcomes in rheumatic disease patients with coronavirus disease 2019 (COVID-19) and compare results to uninfected patients.
    keywords: covid-19; disease; license; medrxiv; patients; preprint
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        item: #4273 of 7819
          id: cord-308218-0rztvk9g
      author: Dunham, Alexandra M.
       title: A Bioethical Perspective for Navigating Moral Dilemmas Amidst the COVID-19 Pandemic
        date: 2020-04-10
       words: 3679
      flesch: 41
     summary: The Centers for Disease Control and Prevention addresses the question of COVID-19 patient care for pregnant healthcare workers by placing the burden on facilities to consider limiting exposure to confirmed or suspected COVID-19, especially during higher risk procedures but acknowledges challenges of staffing availability. What are we, as individual clinicians, morally required to do, given the circumstance?
    keywords: care; clinicians; covid-19; ethics; health; pandemic; patient
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        item: #4274 of 7819
          id: cord-308252-qwoo7b1l
      author: Cardinale, Vincenzo
       title: Intestinal permeability changes with bacterial translocation as key events modulating systemic host immune response to SARS-CoV-2: A working hypothesis
        date: 2020-09-16
       words: 4606
      flesch: 30
     summary: As previously demonstrated in SARS-CoV-1, gastrointestinal manifestations are significant extrapulmonary complaints in Covid-19 patients [8] [9] [10] [11] . Covid-19 patients are at a high risk of both venous and arterial thromboembolism
    keywords: coronavirus; cov-2; covid-19; damage; disease; gut; infection; liver; patients; response; sars; syndrome
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        item: #4275 of 7819
          id: cord-308256-jy20xtwx
      author: Wells, P. M.
       title: Estimates of the rate of infection and asymptomatic COVID-19 disease in a population sample from SE England
        date: 2020-07-30
       words: 4269
      flesch: 45
     summary: Symptom profiling included core COVID-19 symptoms and general symptoms, in addition to algorithm prediction of prior COVID-19. Of 48 seropositive individuals with full symptom data, nine (19%) were fully asymptomatic, and 16 (27%) were asymptomatic for core COVID-19 symptoms: fever, cough or anosmia.
    keywords: antibody; app; cov-2; covid-19; participants; preprint; sars; study; symptoms
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        item: #4276 of 7819
          id: cord-308263-stnv5oip
      author: Rosen, Raphael J.
       title: Thrombotic complications in critically ill patients with COVID 19
        date: 2020-04-30
       words: 332
      flesch: 45
     summary: key: cord-308263-stnv5oip authors: Rosen, Raphael J. title: Thrombotic complications in critically ill patients with COVID 19 date: 2020-04-30 journal: Thromb Res DOI: 10.1016/j.thromres.2020.04.032 sha: doc_id: 308263 cord_uid: stnv5oip nan J o u r n a l P r e -p r o o f To the Editor, Klok et al.(1) provide important insight into the coagulopathy that complicates COVID 19. They report an alarmingly high number of thrombotic complications (combination venous and arterial thromboembolism) in critically ill patients with COVID 19.
    keywords: patients
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        item: #4277 of 7819
          id: cord-308270-343r91km
      author: Sawlani, V.
       title: COVID-19-related intracranial imaging findings: a large single-centre experience
        date: 2020-09-15
       words: 1967
      flesch: 36
     summary: Using electron microscopy, SARS-CoV-2 viral elements have been demonstrated within endothelial cells themselves, associated with profound inflammation and tissue oedema in COVID-19 patients at autopsy key: cord-308270-343r91km authors: Sawlani, V.; Scotton, S.; Jacob, S.; Nader, K.; Jen, J. P.; Patel, M.; Gokani, K.; Denno, P.; Thaller, M.; Englezou, C.; Janjua, U.; Bowen, M.; Hoskote, C.; Veenith, T.; Hassan-Smith, G. title: COVID-19-related intracranial imaging findings: a large single-centre experience date: 2020-09-15 journal: Clin Radiol DOI: 10.1016/j.crad.2020.09.002 sha: doc_id: 308270 cord_uid: 343r91km Aim To describe the neuroradiological changes in patients with coronavirus disease 2019 (COVID-19).
    keywords: acute; brain; covid-19; imaging; patients
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        item: #4278 of 7819
          id: cord-308271-zzepl3on
      author: Calderón-Larrañaga, Amaia
       title: COVID-19: risk accumulation among biologically and socially vulnerable older populations
        date: 2020-08-17
       words: 2537
      flesch: 39
     summary: Based on preliminary data from Sweden and other reports, in this paper we propose a conceptual framework whereby different factors related to biological and social vulnerability may explain the specific COVID-19 burden among older people. Up to one quarter of the deaths due COVID-19 have been in older people aged 70-79 years and up to two thirds in those over 80 years, regardless of the incidence of the disease or the completeness in the ascertainment of deaths across countries ( Table 1) .
    keywords: adults; care; covid-19; data; health; income; people
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        item: #4279 of 7819
          id: cord-308293-8y2iaqnl
      author: Singh, Vijay P.
       title: What underlies the benefit of famotidine formulations used during COVID-19?
        date: 2020-08-07
       words: 777
      flesch: 34
     summary: The study was based on computational modelling, which proposed famotidine might inhibit viral replication through direct interaction with the 3-chymotrypsin-like protease 2 , and was also preceded by a small, short-term follow-up, outpatient study suggesting that famotidine use was associated with symptomatic improvement 3 . key: cord-308293-8y2iaqnl authors: Singh, Vijay P.; El-Kurdi, Bara; Rood, Christopher title: What underlies the benefit of famotidine formulations used during COVID-19? date: 2020-08-07 journal: Gastroenterology DOI: 10.1053/j.gastro.2020.07.051 sha: doc_id: 308293 cord_uid: 8y2iaqnl nan This letter is in reference to the study by Freedberg et al 1
    keywords: covid-19; famotidine; study
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        item: #4280 of 7819
          id: cord-308303-tgpqnoq2
      author: Liu, X.
       title: Heparin-induced thrombocytopenia is associated with a high risk of mortality in critical COVID-19 patients receiving heparin-involved treatment
        date: 2020-04-28
       words: 4581
      flesch: 42
     summary: Every patient had stayed in the intensive care unit for more than three days (herein and after referred to as ICU patients) and had at least three consecutively detected platelet counts data. As shown in table 1, severe thrombocytopenia (PLT≤50×10 9 /L) was observed in 1·1% of non-ICU patients (1/93), whereas it occurred in 41% of ICU patients (25/61), of whom 96% were ICU nonsurvivors (24/25).
    keywords: covid-19; crrt; figure; heparin; hit; icu; patients; plt; thrombocytopenia
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        item: #4281 of 7819
          id: cord-308354-p50vs2eb
      author: Martinsson, Lisa
       title: Were clinical routines for good end-of-life care maintained in hospitals and nursing homes during the first three months of the outbreak of COVID-19? A national register study
        date: 2020-10-07
       words: 4271
      flesch: 55
     summary: Even before the pandemic, there was ongoing work in Europe to implement palliative care for the growing group of care home residents (28). Symptom control is central to end-of-life care and is included in the definition of palliative care from the World Health Organization (8) .
    keywords: care; covid-19; end; homes; life; nursing; palliative
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        item: #4282 of 7819
          id: cord-308357-sjravgng
      author: Mariania, Silvia
       title: Out of Hospital Management of LVAD Patients During COVID‐19 Outbreak
        date: 2020-05-28
       words: 1315
      flesch: 37
     summary: key: cord-308357-sjravgng authors: Mariania, Silvia; Schmittoa, Jan D. title: Out of Hospital Management of LVAD Patients During COVID‐19 Outbreak date: 2020-05-28 journal: Artif Organs DOI: 10.1111/aor.13744 sha: doc_id: 308357 cord_uid: sjravgng Coronavirus disease 2019 (COVID‐19) has been declared a pandemic touching thousands of patients all around the world. Nevertheless, the COVID‐19 pandemic led to a drastic reduction of routine clinical activities and a consequent risk of looser connections between LVAD patients and their referring center.
    keywords: center; covid-19; lvad; patients
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        item: #4283 of 7819
          id: cord-308358-2bap7iih
      author: Friedland, Robert P
       title: The role for the metagenome in the pathogenesis of COVID-19
        date: 2020-10-07
       words: 1126
      flesch: 32
     summary: In a relatively short time, several major advances in the field led to the decoding of the viral genome, and modes of transmission, as well as mechanisms of immune response to the infection that mostly succeeds in clearance [2] . The intestinal microbiota fuelling metabolic inflammation Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia Microbiota-driven tonic interferon signals in lung stromal cells protect from influenza virus infection Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia Microbiota-dependent signals are required to sustain TLR-mediated immune responses Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans The intermucosal connection between the mouth and gut in commensal pathobiont-driven colitis Dysbiosis in the gut, nose, oropharynx and lungs may initiate and worsen these pathogenic processes.
    keywords: covid-19; immune; microbiota; response
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        item: #4284 of 7819
          id: cord-308364-4u4woek3
      author: Akkineni, Sisir
       title: Percutaneous Tracheostomy in COVID-19 Patients: The Miami Model
        date: 2020-09-28
       words: 1262
      flesch: 44
     summary: Some of the modifications to decrease aerosolization in COVID-19 patients during percutaneous tracheostomy reported in literature include exchanging the ETT to a smaller 6mm internal diameter tube prior to the procedure and keeping the cuff inflated at the carina while the operator worked around the ETT during tracheal cannulation We hope to provide proceduralists with a specific method for percutaneous tracheostomies that is both safe for the patient and provider.
    keywords: covid-19; patients; tracheostomy; tube
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        item: #4285 of 7819
          id: cord-308376-un4ztqf4
      author: Bakken, Suzanne
       title: Informatics is a critical strategy in combating the COVID-19 pandemic
        date: 2020-06-05
       words: 1398
      flesch: 26
     summary: Health informatics support for outbreak management in an academic health system Rapid design and implementation of an integrated patient self-triage and self-scheduling tool for COVID-19 Electronic personal protective equipment: a strategy to protect emergency department providers in the age of COVID-19 Balancing health privacy, health information exchange, and research in the context of the COVID-19 pandemic Construction of 5G all-wireless network and information system for cabin hospitals Telehealth transformation: COVID-19 and the rise of virtual care Use of self-administered surveys through QR code and same center telemedicine in a walk-in clinic in the era of COVID-19 Domains, tasks, and knowledge for health informatics practice: results of a practice analysis Domains, tasks, and knowledge for clinical informatics subspecialty practice: results of a practice analysis Doing what matters most None declared. 9 As compared with the latter, which focused on physicians, the focus of Gadd et al 8 is on health informatics professionals comprising practitioners with clinical (eg, dentistry, nursing, pharmacy), public health, health informatics, or computer science training.
    keywords: covid-19; health; informatics; pandemic; practice
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        item: #4286 of 7819
          id: cord-308383-j1gi1cxu
      author: Xu, Jie
       title: Associations of Stay-at-Home Order and Face-Masking Recommendation with Trends in Daily New Cases and Deaths of Laboratory-Confirmed COVID-19 in the United States
        date: 2020-07-08
       words: 3515
      flesch: 49
     summary: The quasi-experimental interrupted time series study-design is likely the most rigorous method available for when randomization and controlling are not possible, 12,13,19 as the case for when COVID-19 SAHO and face-masking were implemented in the USA. Multivariable piecewise log-linear regression revealed the states’ neighboring relationship with New York was linked to COVID-19 daily new cases and deaths.
    keywords: april; cases; covid-19; deaths; new; saho; states
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        item: #4287 of 7819
          id: cord-308402-37i62atc
      author: Barnes, Betsy J.
       title: Targeting potential drivers of COVID-19: Neutrophil extracellular traps
        date: 2020-04-16
       words: 3927
      flesch: 29
     summary: Key enzymes in the formation of NETs are: neutrophil elastase (NE), which degrades intracellular proteins and triggers nuclear disintegration; peptidyl arginine deiminase type 4 (PAD4), which citrullinates histones to facilitate the decondensation and release of the chromosomal DNA; and gasdermin D, which generates pores in the membrane of the neutrophil, thereby facilitating cell membrane rupture and the expulsion of DNA and the associated molecules Kaplan and Radic, 2012; Papayannopoulos, 2018; Papayannopoulos et al., 2010; Rohrbach et al., 2012; Sollberger et al., 2018) . ; Xu et al., 2015) .
    keywords: ards; covid-19; disease; et al; extracellular; formation; histones; lung; nets; neutrophil; patients; traps
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        item: #4288 of 7819
          id: cord-308409-0n2ysgsa
      author: Pawlak, Katarzyna M.
       title: Impact of COVID-19 on endoscopy trainees: an international survey
        date: 2020-06-11
       words: 3539
      flesch: 31
     summary: key: cord-308409-0n2ysgsa authors: Pawlak, Katarzyna M.; Kral, Jan; Khan, Rishad; Amin, Sunil; Bilal, Mohammad; Lui, Rashid N.; Sandhu, Dalbir S.; Hashim, Almoutaz; Bollipo, Steven; Charabaty, Aline; de-Madaria, Enrique; Rodríguez-Parra, Andrés Felipe; Sánchez-Luna, Sergio A.; Żorniak, Michał; Walsh, Catharine M.; Grover, Samir C.; Siau, Keith title: Impact of COVID-19 on endoscopy trainees: an international survey date: 2020-06-11 journal: Gastrointest Endosc DOI: 10.1016/j.gie.2020.06.010 sha: doc_id: 308409 cord_uid: 0n2ysgsa nan The coronavirus disease 2019 (COVID-19) pandemic has had a profound impact on the provision of GI endoscopy services worldwide, with the radical curtailment of elective procedures to restrict disease transmission. The COVID-19 pandemic creates challenges for endoscopy trainees for several reasons.
    keywords: anxiety; covid-19; endoscopy; impact; pandemic; ppe; survey; trainees; training
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        item: #4289 of 7819
          id: cord-308424-crvnzr44
      author: Mascarenhas, Victor Hugo Alves
       title: Care recommendations for parturient and postpartum women and newborns during the COVID-19 pandemic: a scoping review
        date: 2020-08-10
       words: 4499
      flesch: 36
     summary: Essential nutrition actions: improving maternal, newborn, infant and young child health and nutrition Q&A: COVID-19 and pregnancy and childbirth Dispõe sobre a adoção de medidas adicionais, de caráter temporário e emergencial, de prevenção de contágio pelo COVID-19 Guidance for conducting systematic scoping reviews Scoping studies: towards a methodological framework The Joanna Briggs Institute PRISMA Extension for scoping reviews (PRISMA-ScR): checklist and explanation Coronavirus disease 2019 (COVID-19) and pregnancy: what obstetricians need to know Coronavirus disease 2019 (COVID-19) pandemic and pregnancy Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan Expert consensus for managing pregnant women and neonates born to mothers with suspected or confirmed novel coronavirus (COVID-19) infection Experience of clinical management for pregnant women and newborns with novel coronavirus pneumonia in Tongji Hospital, China Safe delivery for COVID-19 infected pregnancies Pregnancy and perinatal outcomes of women with coronavirus disease (COVID-19) pneumonia: a preliminary analysis Novel corona virus disease (COVID-19) in pregnancy: what clinical recommendations to follow? Safety and efficacy of different anesthetic regimens for parturients with COVID-19 undergoing cesarean delivery: a case series of 17 patients Impact of COVID-19 infection on pregnancy outcomes and the risk of maternalto-neonatal intrapartum transmission of COVID-19 during natural birth Clinical and CT imaging features of the COVID-19 pneumonia: focus on pregnant women and children Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia Novel coronavirus infection and pregnancy From the frontline of COVID-19 -how prepared are we as obstetricians: a commentary t i ve s concerning donor milk banking during the SARS-CoV-2 www COVID-19) pandemic Emergency cesarean section on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) confirmed patient Maternal deaths with Covid-19: a different outcome from mid to low resource countries? Coordenadoria de Controle de Doenças (CCD-SP). key: cord-308424-crvnzr44 authors: Mascarenhas, Victor Hugo Alves; Caroci-Becker, Adriana; Venâncio, Kelly Cristina Máxima Pereira; Baraldi, Nayara Girardi; Durkin, Adelaide Caroci; Riesco, Maria Luiza Gonzalez title: Care recommendations for parturient and postpartum women and newborns during the COVID-19 pandemic: a scoping review date: 2020-08-10 journal:
    keywords: care; childbirth; cov-2; covid-19; health; infection; mothers; sars; women
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        item: #4290 of 7819
          id: cord-308431-l4sv28hj
      author: Schindler, Seth
       title: Covid-19, China and the future of global development
        date: 2020-08-04
       words: 7016
      flesch: 48
     summary: South China Morning Post China urges World Bank to suspend debt payments for poorest countries Mnuchin says IMF and World Bank funds won't repay debts to China The Specter of Global China: Politics, Labor, and Foreign Investment in Africa The Rise and Fall of Development Theory Demystifying Chinese overseas investment in infrastructure: Port development, the Belt and Road Initiative and regional development U.S. and China turn coronavirus into a geopolitical football World Bank Group President Malpass: Remarks to the Development Committee South-South cooperation 3.0?: key: cord-308431-l4sv28hj authors: Schindler, Seth; Jepson, Nicholas; Cui, Wenxing title: Covid-19, China and the future of global development date: 2020-08-04 journal: nan DOI: 10.1016/j.resglo.2020.100020 sha: doc_id: 308431 cord_uid: l4sv28hj Abstract Tensions between the United States and China have been escalating in recent years, and the Covid-19 pandemic has intensified their competition.
    keywords: american; bank; china; chinese; countries; covid-19; crisis; debt; development; economic; example; global; government; leadership; policy; post; world
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        item: #4291 of 7819
          id: cord-308473-x2tfx8l9
      author: Zhang, Xiu-jie
       title: COVID-19: What is next for nursing in public health emergency?
        date: 2020-06-12
       words: 649
      flesch: 48
     summary: key: cord-308473-x2tfx8l9 authors: Zhang, Xiu-jie; Shi, Tie-ying; Sun, Li title: COVID-19: What is next for nursing in public health emergency? date: 2020-06-12 journal: Nurse Educ Pract DOI: 10.1016/j.nepr.2020.102821 sha: doc_id: 308473 cord_uid: x2tfx8l9 nan More than 2.8 million confirmed cases of COVID-19 have now been reported to WHO, including more than 198,668 deaths, resulting in a public health emergency that has swept the world (WHO., 2020). On the other hand, the management of artificial airway, First, it is important to strengthen the training of specialized nursing talents, broaden the nursing professional field, and carry out education and training on public health emergencies.
    keywords: health; nurses
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        item: #4292 of 7819
          id: cord-308476-pyje6txy
      author: Campochiaro, Corrado
       title: The conundrum of interleukin-6 blockade in COVID-19
        date: 2020-08-14
       words: 861
      flesch: 32
     summary: COVID-19: consider cytokine storm syndromes and immunosuppression Interleukin 1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study GM-CSF blockade with mavrilimumab in severe COVID-19 pneumonia and systemic hyperinflammation: a single-centre, prospective cohort study Targeting IL-1, IL-6 or GM-CSF in COVID-19 Efficacy and safety of tocilizumab in severe COVID-19 patients: a single-centre retrospective cohort study Tocilizumab in patients with severe COVID-19: a retrospective cohort study Interleukin-6 blockade with sarilumab in severe COVID-19 pneumonia with systemic hyperinflammation: an open-label cohort study Tocilizumab among patients with COVID-19 in the intensive care unit: a multicentre observational study Characteristics, treatment, outcomes and cause of death of invasively ventilated patients with COVID-19 ARDS in key: cord-308476-pyje6txy authors: Campochiaro, Corrado; Dagna, Lorenzo title: The conundrum of interleukin-6 blockade in COVID-19 date: 2020-08-14 journal: The Lancet Rheumatology DOI: 10.1016/s2665-9913(20)30287-3 sha: doc_id: 308476 cord_uid: pyje6txy nan Since the very first cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection were identified in China, patients with severe manifestations of COVID-19 have been shown to develop a hyperinflammatory syndrome resembling that seen in patients with either macrophage-activation syndrome or cytokinerelease syndrome associated with chimeric antigen receptor T-cell therapy.
    keywords: covid-19; patients; tocilizumab
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        item: #4293 of 7819
          id: cord-308491-fc46k594
      author: Mossa-Basha, Mahmud
       title: Policies and Guidelines for COVID-19 Preparedness: Experiences from the University of Washington
        date: 2020-04-08
       words: 3312
      flesch: 45
     summary: We have created scanner throughput plans, including designated CT scanners and imaging suites for COVID-19 positive patients. At our hospitals, imaging rooms are 8 closed for 1 hour for airborne precautions in rooms with a minimum of 6 air exchanges per hour.
    keywords: air; care; covid-19; hospital; imaging; patient; radiology; room
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        item: #4294 of 7819
          id: cord-308527-scxemthv
      author: Barauna, V. G.
       title: Ultra-rapid on-site detection of SARS-CoV-2 infection using simple ATR-FTIR spectroscopy and analysis algorithm: high sensitivity and specificity
        date: 2020-11-04
       words: 4225
      flesch: 43
     summary: ; https://doi.org/10.1101/2020.11.02.20223560 doi: medRxiv preprint control saliva in comparison with saliva spiked inactivated virus particle at various copy number levels highlighted an ability to detect virus particle-induced spectral alterations at levels that would be considered extremely low in the pharyngeal cavity of infected humans (symptomatic or asymptomatic). ; https://doi.org/10.1101/2020.11.02.20223560 doi: medRxiv preprint spectral data space to principal components (PCs) responsible for the majority of variance in the original dataset.
    keywords: copyright; holder; license; medrxiv; medrxiv preprint; november; preprint; review; saliva; virus
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        item: #4295 of 7819
          id: cord-308545-5n55yl2s
      author: Verscheijden, Laurens F. M.
       title: Chloroquine Dosing Recommendations for Pediatric COVID‐19 Supported by Modeling and Simulation
        date: 2020-05-21
       words: 2704
      flesch: 48
     summary: The aim of our study was to establish best‐evidence to inform pediatric CHQ doses for children infected with COVID‐19. If currently ongoing studies show more optimal dosing regimens in adults for COVID-19, we will reconsider pediatric doses using the same concept of exposure-matching informed by PBPK modeling.
    keywords: adults; children; chq; dose; pediatric
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        item: #4296 of 7819
          id: cord-308597-ieju8gd8
      author: de Carvalho, Renata Cristina
       title: The interference of COVID-19 in the male reproductive system: Important questions and the future of assisted reproduction techniques
        date: 2020-08-21
       words: 1155
      flesch: 35
     summary: No evidence of severe acute respiratory syndrome-coronavirus 2 in semen of males recovering from coronavirus disease 2019 Absence of 2019 novel coronavirus in semen and testes of COVID-19 patients Clinical Characteristics and Results of Semen Tests Among Men With Coronavirus Disease COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis History of febrile illness and variation in semen quality Influence of genital heat stress on semen quality in humans Taking into account all this information, several issues around the Coronavirus to semen and male fertility relationships are being raised, including: Can SARS-Cov-2 be found in semen?
    keywords: coronavirus; covid-19; sars; semen
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        item: #4297 of 7819
          id: cord-308615-4fobikeh
      author: AKTAS, Busra
       title: Gut-lung axis and dysbiosis in COVID-19
        date: 2020-06-21
       words: 4224
      flesch: 34
     summary: Microbiome evolution during host aging The gut microbiota as an environmental factor that regulates fat storage Altered microbiota in cirrhosis and its relationship to the development of infection Bile acids in physico-chemical host defence Immuno-microbiota cross and talk: The new paradigm of metabolic diseases Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study The presence of SARS-CoV-2 RNA in the feces of COVID-19 patients Diarrhea during COVID-19 infection: pathogenesis, epidemiology, prevention and management Inactivation of the coronavirus that induces severe acute respiratory syndrome, SARS-CoV Gut-origin sepsis: Evolution of a concept Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome Is SARS-CoV-2 also an enteric pathogen with potential fecal-oral transmission: A COVID-19 virological and clinical review Increased intestinal permeability is associated with the development of multiple organ dysfunction syndrome in critically ill ICU patients Anti-HCV, nucleotide inhibitors, repurposing against COVID-19 Lung microbiota in the acute respiratory disease: from coronavirus to metabolomics COVID-19 and liver dysfunction: current insights and emergent therapeutic strategies Metagenomic analysis of the human distal gut microbiome Multiple organ infection and the pathogenesis of SARS Clinical characteristics of coronavirus disease 2019 in China Respiratory viral infection-induced microbiome alterations and secondary bacterial pneumonia Probiotics in the prevention of antibioticassociated diarrhoea and Clostridium difficile infection From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses First case of 2019 novel coronavirus in the United States Clinical features of patients infected with 2019 novel coronavirus in Wuhan Dysbiosis of the gut and lung microbiome has a role in asthma Population-level COVID-19 mortality risk for non-elderly individuals overall and for non-elderly individuals without underlying diseases in pandemic epicenters Considering the effects of microbiome and diet on SARS-CoV-2 infection: Nanotechnology roles Pulmonary-intestinal crosstalk in mucosal inflammatory disease T Cell responses to whole SARS coronavirus in humans Molecular immune pathogenesis and diagnosis of COVID-19 Diarrhoea may be underestimated: A missing link in 2019 novel coronavirus Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection Coronavirus covid-19 has killed more people than SARS and MERS combined, despite lower case fatality rate Gut microbiota and liver disease Antimicrobial peptides and gut microbiota in homeostasis and pathology Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: A descriptive, cross-sectional, multicenter study The SARS, MERS and novel coronavirus (COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned? COVID-19 patients with digestive symptoms tend to experience liver injury more than those of without digestive symptoms (Pan et al., 2020) .
    keywords: cov-2; covid-19; et al; gut; microbiota; patients; sars
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        item: #4298 of 7819
          id: cord-308616-tyd50s4m
      author: Bizri, Abdul Rahman
       title: COVID-19 Pandemic: An Insult Over Injury for Lebanon
        date: 2020-07-13
       words: 4037
      flesch: 48
     summary: The incidence rate of COVID-19 cases in Lebanon was 208/million persons, with a mortality rate of 5/million persons. RHUH, the largest public hospital in Lebanon, was assigned to be the main medical center for diagnosing and managing suspected and confirmed COVID-19 cases.
    keywords: cases; country; covid-19; health; lebanese; lebanon; number; patients; quarantine
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        item: #4299 of 7819
          id: cord-308648-bus3axay
      author: He, Shan
       title: Analysis of Risk Perceptions and Related Factors Concerning COVID-19 Epidemic in Chongqing, China
        date: 2020-06-26
       words: 3120
      flesch: 47
     summary: Media information sources, including community information platforms and community workers may cause the increase of public risk perceptions. During the disease control and prevention, public risk perceptions are widely accompanied with the attitudes, emotional response and prevention behaviors, which have an impact on the evolution of emergencies [10] .
    keywords: covid-19; health; information; perceptions; public; residents; risk
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        item: #4300 of 7819
          id: cord-308667-6jr3z9wx
      author: Papachristodoulou, Eleni
       title: Long-term and herd immunity against SARS-CoV-2: implications from current and past knowledge
        date: 2020-06-08
       words: 1769
      flesch: 39
     summary: An interactive web-based dashboard to track COVID-19 in real time Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period Herd immunity -estimating the level required to halt the COVID-19 epidemics in affected countries Epidemiological trends of COVID-19 epidemic in Italy during Positive RT-PCR test results in patients recovered from COVID-19 A case of a readmitted patient who recovered from COVID-19 in Chengdu Vaccination-induced herd immunity: successes and challenges Longitudinal profile of antibodies against SARS-coronavirus in SARS patients and their clinical significance Immune responses and pathogenesis of SARS-CoV-2 during an outbreak in Iran: comparison with SARS and MERS COVID-19: herd immunity and convalescent plasma transfer therapy Lack of peripheral memory B cell responses in recovered patients with severe acute respiratory syndrome: a six-year follow-up study International expansion of a novel SARS-CoV-2 mutant An interactive online dashboard for tracking COVID-19 in U.S. counties, cities, and states in real time Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered 1 patient cohort and their implications Virological assessment of hospitalized patients with COVID-2019 Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019 Effective herd immunity relies on the percentage of the immune population, the length and effectiveness of the immune response and the stability of the viral epitopes (Mallory, Lindesmith and Baric 2018) .
    keywords: immunity; sars
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        item: #4301 of 7819
          id: cord-308673-dkmpayk4
      author: Ni, Li
       title: Combination of western medicine and Chinese traditional patent medicine in treating a family case of COVID-19 in Wuhan
        date: 2020-03-13
       words: 1717
      flesch: 57
     summary: By February 14, the number of confirmed patients and deaths were 37 914 and 1123, respectively, and the mortality of COVID-19 was 2.96% in Wuhan City, Hubei Province, which is considered as the origin of first cluster of patients [3] . This report suggests that SHL treatment might be effective for COVID-19 and warrants subsequent clinical trials to obtain sufficient evidence for clinical recommendation.
    keywords: case; covid-19; january; shl
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        item: #4302 of 7819
          id: cord-308680-moligska
      author: Wong, Justin
       title: Epidemiological Investigation of the First 135 COVID-19 Cases in Brunei: Implications for Surveillance, Control, and Travel Restrictions
        date: 2020-08-14
       words: 4197
      flesch: 46
     summary: All confirmed COVID-19 cases were treated and isolated at the National Isolation Centre. 2 Importation events in a country with no cases can lead to an exponential increase in case numbers within a short time period.
    keywords: brunei; cases; control; covid-19; days; epidemic; measures; time
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        item: #4303 of 7819
          id: cord-308702-90a4dj76
      author: Hussain, Azhar
       title: Cardiac surgery in patients with confirmed COVID‐19 infection: Early experience
        date: 2020-06-12
       words: 618
      flesch: 41
     summary: We present a case series of three patients who underwent urgent cardiac surgery and who have had recent or active COVID‐19 infection. We present a case series of three patients who underwent urgent cardiac surgery who have had recent or active COVID-19 infection.
    keywords: patients; surgery
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        item: #4304 of 7819
          id: cord-308715-uo6h1h2e
      author: Chandra, Aman
       title: Personal protective equipment (PPE) for vitreoretinal surgery during COVID-19
        date: 2020-05-12
       words: 1839
      flesch: 37
     summary: Insights into the recent 2019 novel coronavirus (SARS-CoV-2) in light of past human coronavirus outbreaks Pandemic potential of a strain of influenza A (H1N1): early findings Early transmission dynamics in wuhan, china, of novel coronavirusinfected pneumonia Estimation of the reproductive number of novel coronavirus (COVID-19) and the probable outbreak size on the Diamond Princess cruise ship: a data-driven analysis The reproductive number of COVID-19 is higher compared to SARS coronavirus Estimates of the reproduction number for seasonal, pandemic, and zoonotic influenza: a systematic review of the literature Viral dynamics in mild and severe cases of COVID-19 Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand Effectiveness of airport screening at detecting travellers infected with novel coronavirus (2019-nCoV) Estimation of the asymptomatic ratio of novel coronavirus infections (COVID-19) Q&A: similarities and differences-COVID-19 and influenza Serial interval of novel coronavirus (COVID-19) infections Asymptomatic and human-to-human transmission of SARS-CoV-2 in a 2-family cluster COVID-19: protecting health-care workers Facing COVID-19 in Ophthalmology department Vitreoretinal Surgery During COVID-19 Pandemic (Royal College of Ophthalmologists Particle size-selective assessment of protection of European standard FFP respirators and surgical masks against particlestested with human subjects Infection Prevention and Control Recommendations for Patients with Suspected or Confirmed Coronavirus Disease 2019 (COVID-19) in Healthcare Settings Rational use of personal protective equipment for coronavirus disease 2019 (COVID-19 Recommended PPE for healthcare workers by secondary care inpatient clinical setting, NHS and independent sector Pathogenesis of COVID-19 from a cell biology perspective Factors involved in the aerosol transmission of infection and control of ventilation in healthcare premises Recognition of aerosol transmission of infectious agents: a commentary Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study Influenza virus in human exhaled breath: an observational study Exhalation of respiratory viruses by breathing, coughing, and talking Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection Characteristics of ocular findings of patients with coronavirus disease 2019 (COVID-19) in Hubei Province, China Aerosol generating procedures and risk of transmission of acute respiratory infections to healthcare workers: a systematic review Aerosol and Surface Stability of SARS-CoV-2 as compared with SARS-CoV-1 Environmental and body contamination through aerosols produced by high-speed cutters in lumbar spine surgery AGPs involving the upper respiratory tract including endotracheal intubation and airway suction are recognised to be associated with an increased risk of SARS transmission to healthcare workers [30] including SARS-CoV-2 [31] but the risks from other anatomical sites are less clear.
    keywords: coronavirus; cov-2; covid-19; patients; sars; transmission
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        item: #4305 of 7819
          id: cord-308730-mv3ttl1e
      author: Bujanda, Luis
       title: Surgery and emergency gastrointestinal endoscopy during the Covid-19 pandemic
        date: 2020-09-16
       words: 913
      flesch: 51
     summary: The percentage of emergency endoscopies that required some therapeutic procedure went from 47% (40/85) in the preCovid period to 47% (21/45) in the Covid period ( Table 1 ). The number of UGE by upper gastrointestinal bleeding fell from 33 patients in the pre-Covid period to 23 patients in the Covid period, that is, a 30% less.
    keywords: covid; period
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        item: #4306 of 7819
          id: cord-308740-06jr58kz
      author: Lazaridis, Charalampos
       title: Involvement of Cardiovascular System As The Critical Point in Coronavirus Disease 2019 (COVID-19) Prognosis and Recovery
        date: 2020-06-10
       words: 2544
      flesch: 20
     summary: Finally, we summarize current knowledge on therapeutic modalities and recommendations by scientific societies and experts regarding the cardiovascular management of COVID-19 patients. Similarly, an aberrant T-cell and monocyte response has been observed in COVID-19 patients leading to a systemic hyper-inflammatory response characterized by increased proinflammatory cytokine and chemokine production (tumor necrosis factor, IL-2, IL-6, IL-7 and CCL2 among others) 34, 48, 50, 68, 69 (Table 5) , (Figure 2 The binding of SARS-CoV-2 to ACE2 is expected to lead to internalization of ACE2 and loss of the external ACE2 catalytic effect 24, 93 .
    keywords: ace2; coronavirus; cov-2; covid-19; disease; novel; patients; sars
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        item: #4307 of 7819
          id: cord-308762-lxhq9ga4
      author: Sharma, Manoj Kumar
       title: Researcher Burnout: An Overlooked Aspect in Mental Health Research in times of COVID-19
        date: 2020-08-25
       words: 1672
      flesch: 33
     summary: This indicates that COVID-19 is relevant to the field of mental health and mental health aspects of COVID-19 need to be investigated among all kinds of health professionals including researchers working in the field of mental health research (Tandon, 2020) . Thus, there appears to be a need for novel and innovative research approaches to explore the burnout and mental health needs among mental health researchers and to actively create mechanisms for its management and especially during the challenging times of a pandemic like COVID-19.
    keywords: burnout; covid-19; health; research; researchers
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        item: #4308 of 7819
          id: cord-308803-i934doud
      author: PONNAPA REDDY, M.
       title: Prone positioning of non-intubated patients with COVID-19 - A Systematic Review and Meta-analysis
        date: 2020-10-14
       words: 4160
      flesch: 41
     summary: Necessity Is the Mother of Invention Prone position for acute respiratory failure in adults Prone positioning improves oxygenation in spontaneously breathing nonintubated patients with hypoxemic acute respiratory failure: A retrospective study Prone positioning in non-intubated patients with COVID-19: raising the bar Efficacy of early prone position for COVID-19 patients with severe hypoxia: a single-center prospective cohort study Prone positioning combined with high-flow nasal or conventional oxygen therapy in severe Covid-19 patients Alternatives to Invasive Ventilation in the COVID-19 Pandemic Relationship between gas exchange response to prone position and lung recruitability during acute respiratory failure Prone position improves mechanics and alveolar ventilation in acute respiratory distress syndrome COVID-19 Does Not Lead to a Typical Preferred reporting items for systematic reviews and metaanalyses: the PRISMA statement COAP Living Evidence on COVID-19 Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barre syndrome: From systematic review to living systematic review Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses Ottawa2013 Methodological quality of case series studies Correlation between the levels of SpO2and PaO2 Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range Metaprop: a Stata command to perform meta-analysis of binomial data Measuring inconsistency in meta-analyses Bias in meta-analysis detected by a simple, graphical test Feasibility and physiological effects of prone positioning in non-intubated patients with acute respiratory failure due to COVID-19 (PRON-COVID): a prospective cohort study Prone Positioning of Non-Intubated Patients with COVID-19 Reduced ICU demand with early CPAP and proning in COVID-19 at Bradford: a single centre cohort Early awake prone position combined with high-flow nasal oxygen therapy in severe COVID-19: a case series Prone positioning in high-flow nasal cannula for COVID-19 patients with severe hypoxemia: a pilot study Prone Positioning in Awake, Nonintubated Patients With COVID-19 Hypoxemic Respiratory Failure Respiratory Parameters in Patients With COVID-19 After Using Noninvasive Ventilation in the Prone Position Outside the Intensive Care Unit Prone and Lateral Positioning in Spontaneously Breathing Patients With COVID-19 key: cord-308803-i934doud authors: PONNAPA REDDY, M.; SUBRAMANIAM, A.; LIM, Z. J.; ZUBAREV, A.; AFROZ, A.; BILLAH, B.; TIRUVOIPATI, R.; RAMANATHAN, K.; WONG, S. N.; BRODIE, D.; FAN, E.; SHEKAR, K. title: Prone positioning of non-intubated patients with COVID-19 - A Systematic Review and Meta-analysis date: 2020-10-14 journal: nan DOI: 10.1101/2020.10.12.20211748 sha: doc_id: 308803 cord_uid: i934doud Purpose: Several studies have reported adopting prone positioning (PP) in non-intubated patients with COVID-19-related hypoxaemic respiratory failure.
    keywords: covid-19; license; oxygenation; patients; preprint; review; studies
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        item: #4309 of 7819
          id: cord-308807-9yggo5yk
      author: Zheng, DavidX.
       title: National analysis of COVID-19 and older emergency physicians
        date: 2020-11-04
       words: 609
      flesch: 44
     summary: Given the association between advanced age and COVID-19 severity, 2 our objective was to compare the geographic distribution of U.S. EPs age  60 years to the cumulative distribution of confirmed COVID-19 cases, to highlight the potential risks faced by this vulnerable population of clinicians. States were grouped into color-coordinated quintiles based on relative proportion of older EPs, and cumulative COVID-19 case volumes were adjusted with a logarithmic scale to create proportionally-sized data points.
    keywords: covid-19; eps
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        item: #4310 of 7819
          id: cord-308808-9nol6rb4
      author: Mehrpour, Omid
       title: Toll of acute methanol poisoning for preventing COVID-19
        date: 2020-05-27
       words: 583
      flesch: 42
     summary: Subsequently, hospitals encountered a spike in the referral of poisoning cases for the ingestion of industrial-grade ethanol, resulting in an unprecedented high death toll due to alcohol poisoning. Goral J, Karavitis J, Kovacs EJ (2008) Toxic alcohol ingestions: clinical features, diagnosis, and management Dysregulation of immune response in patients with COVID-19 in Wuhan, China
    keywords: alcohol; covid-19
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        item: #4311 of 7819
          id: cord-308813-4ah3cdph
      author: Bartlett, Robert H.
       title: Initial ELSO Guidance Document: ECMO for COVID-19 Patients with Severe Cardiopulmonary Failure
        date: 2020-04-01
       words: 1681
      flesch: 43
     summary: Guidance documents addressing additional portions of ECMO care are currently being assembled for rapid publication and distribution to ECMO centers worldwide. Guidance documents addressing additional portions of ECMO care are currently being assembled for rapid publication and distribution to ECMO centers worldwide.
    keywords: centers; covid-19; ecmo; patients
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        item: #4312 of 7819
          id: cord-308848-chvvtr0d
      author: Fidel, Paul L.
       title: Reply to Özdemir, “Measles-Mumps-Rubella Vaccine and COVID-19 Relationship”
        date: 2020-09-22
       words: 559
      flesch: 28
     summary: Could an unrelated live attenuated vaccine serve as a preventive measure to dampen septic inflammation associated with COVID-19 infection? Significantly improved COVID-19 outcomes in countries with higher BCG vaccination coverage: a multivariable analysis Exploratory analysis of immunization records highlights decreased SARS-CoV-2 rates in individuals with recent non-COVID-19 vaccinations Candida/Staphylococcal polymicrobial intra-abdominal infection: pathogenesis and perspectives for a novel form of trained innate immunity Homologous protein domains in SARS-CoV-2 and measles, mumps and rubella viruses: preliminary evidence that MMR vaccine might provide protection against COVID-19 MMR vaccine appears to confer strong protection from COVID-19: few deaths from SARS-CoV-2 in highly vaccinated populations Immune protection against lethal fungal-bacterial intra-abdominal infections Can a century-old TB vaccine steel the immune system against the new coronavirus Spectrum of trained innate immunity induced by low-virulence Candida species against lethal polymicrobial intra-abdominal infection Epidemiology of COVID-19 among children in China Detection of Covid-19 in children in early Finally, while it is true that we do not know how long the trained innate immunity persists, the randomized clinical trial of MMR versus placebo in health care workers and the nonhuman primate study that will test MMR or BCG in a model of COVID-19 infection will go far to answer these questions.
    keywords: covid-19; mmr
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        item: #4313 of 7819
          id: cord-308857-otsrexqu
      author: Goel, Saurav
       title: Resilient and Agile Engineering Solutions to Address Societal Challenges such as Coronavirus Pandemic
        date: 2020-05-28
       words: 10617
      flesch: 43
     summary: Antibodies help prevent future infections by detecting the virus and binding to their surfaces signalling the body's immune system to destroy such viruses or virus-infected cells. PSS organic electrochemical transistors for chemical and biological sensors: a mini review COVID-19: A Risk Assessment Perspective Phylogenetic network analysis of SARS-CoV-2 genomes Anti-HIV drug repurposing against SARS-CoV-2 Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Fast Identification of Possible Drug Treatment of Coronavirus Disease-19 (COVID-19) through Computational Drug Repurposing Study Structure of Mpro from COVID-19 virus and discovery of its inhibitors Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals COVID-19:
    keywords: coatings; coronavirus; cov-2; covid-19; detection; disease; drug; figure; infection; line; manufacturing; masks; material; nanoparticles; new; pandemic; patients; people; research; sars; surface; test; use; virus; viruses
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        item: #4314 of 7819
          id: cord-308860-llumyzno
      author: Ramón Martínez Riera, José
       title: ATENCIÓN DOMICILIARIA Y COVID-19. ANTES, DURANTE Y DESPUÉS DEL ESTADO DE ALARMA
        date: 2020-05-15
       words: 3209
      flesch: 35
     summary: Esta Atención Domiciliaria, desarrollada fundamentalmente desde el ámbito de la APS, ha tenido un desigual desarrollo y consideración tanto antes, como durante la implantación del Estado de Alarma ante la pandemia del COVID-19 en nuestro país, pero sin duda es una intervención que parece ajustarse a las necesidades de muchas personas, familias y de la propia comunidad ante una situación que precisa del confinamiento domiciliario de personas sanas, pero susceptibles de contagio, conviviendo con personas contagiadas y sus cuidadoras en situación de aislamiento. En cualquier caso, es importante destacar algunas las recomendaciones a tener en cuenta en la Atención Domiciliaria, pues, el seguimiento de las mismas minimiza los contagios y favorece el seguimiento de las personas contagiadas y de su familia, centradas en el rol de la persona enferma, su persona cuidadora y el resto de convivientes, así como en las condiciones de higiene de la vivienda (residuos y limpieza), en base a la guía para el manejo domiciliario del COVID-19 del Ministerio de Sanidad de España (5).
    keywords: aps; atención; care; como; con; covid-19; del; domiciliaria; health; las; los; para; personas; por; que; salud; una
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        item: #4315 of 7819
          id: cord-308892-5gbjdr0u
      author: Fu, Lin
       title: Acute liver injury and its association with death risk of patients with COVID-19: a hospital-based prospective case-cohort study
        date: 2020-04-06
       words: 2673
      flesch: 51
     summary: By multivariate logistic regression, male, older age and lymphocyte reduction were three important independent risk factors predicting ALI among COVID-19 patients. Conclusions: ALI at early stage elevates death risk of COVID-19 patients.
    keywords: ali; covid-19; patients; table
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        item: #4316 of 7819
          id: cord-308906-et7duogt
      author: Di, Gaohong
       title: Simple and Effective Primary Assessment of Emergency Patients in a COVID-19 Outbreak Area: A Retrospective, Observational Study
        date: 2020-08-20
       words: 3675
      flesch: 43
     summary: This result indicated that the preoperative classification system used with emergency patients based on body temperature measurements and chest CT scans was effective for patients who presented mild symptoms or were the incubation period. 2, 5 However, most emergency patients present with fever and leukocytosis, which made it more challenging to screen and identify atypical patients, DovePress asymptomatic patients, and patients who were still in the incubation period for COVID-19 infection.
    keywords: covid-19; crp; emergency; infection; patients; study; surgery; time
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        item: #4317 of 7819
          id: cord-308964-y18nru1d
      author: Couper, Keith
       title: COVID-19 in cardiac arrest and infection risk to rescuers: a systematic review
        date: 2020-04-20
       words: 3366
      flesch: 37
     summary: The aim of this review was to identify the potential risk of transmission associated with key interventions (chest compressions, defibrillation, cardiopulmonary resuscitation) to inform international treatment recommendations. We did not find any direct evidence that chest compressions or defibrillation either are or are not associated with aerosol generation or transmission of infection.
    keywords: chest; compressions; defibrillation; evidence; risk; studies; study; transmission
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        item: #4318 of 7819
          id: cord-308986-eblxpfds
      author: Ferreira-Santos, D.
       title: Identifying baseline clinical features of people with COVID-19
        date: 2020-05-16
       words: 3618
      flesch: 55
     summary: Sample size ranged from 7 to 44 672 participants, with a median of 66 participants per study. When looking at studies from other continents, we observe a smaller range.
    keywords: clinical; covid-19; patients; preprint; studies; study
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        item: #4319 of 7819
          id: cord-308996-tf0v2ojk
      author: Maas, Angela HEM
       title: The Coronavirus Disease 2019 Outbreak Highlights the Importance of Sex-sensitive Medicine
        date: 2020-08-24
       words: 2190
      flesch: 38
     summary: A review Sex and gender differences in myocarditis and dilated cardiomyopathy Sex influences immune responses to viruses, and efficacy of prophylaxis and treatments for viral diseases Sex differences in immune responses The X chromosome and sexspecific effects in infectious disease susceptibility Sex-specific SARS-CoV-2 mortality: among hormone-modulated ACE2 expression, risk of venous thromboembolism and hypovitaminosis D The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2 Risk factors of fatal outcome in hospitalized subjects with coronavirus disease 2019 from a nationwide analysis in China Towards precision management of cardiovascular patients with COVID-19 to reduce mortality Ethnicity and COVID-19: an urgent public health research priority Covid-19: two thirds of healthcare workers who have died were from ethnic minorities At the heart of the matter: unmasking and addressing COVID-19's toll on diverse populations Sex-and gender-specific observations and implications for COVID-19 Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Characteristics of hospitalized adults with COVID-19 in an integrated health care system in California Sex and gender disparities in the COVID-19 pandemic EVAW COVID-19 briefs SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2 Landscape of X chromosome inactivation across human tissues Delayed clearance of SARS-CoV2 in male compared to female patients: high ACE2 expression in testes suggests possible existence of gender-specific viral reservoirs Angiotensin-converting enzyme 2 protects from severe acute lung failure Identification of TMPRSS2 as a susceptibility gene for severe 2009 pandemic A(H1N1) influenza and A(H7N9) influenza Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice Androgen receptor and androgen-dependent gene expression in lung Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options Gender differences in patients with COVID-19: focus on severity and mortality ST-elevation myocardial infarction in patients with COVID-19: clinical and angiographic outcomes EAPCI position statement on invasive management of acute coronary syndromes during the COVID-19 pandemic ST-segment elevation in patients with Covid-19 -a case series Out-of-hospital cardiac arrest during the Covid-19 outbreak in Italy Testosterone to oestradiol ratio reflects systemic and plaque inflammation and predicts future cardiovascular events in men with severe atherosclerosis Sexspecific regulation of inflammation and metabolic syndrome in obesity Renin-angiotensinaldosterone system blockers and the risk of Covid-19 Renin-angiotensinaldosterone system inhibitors and risk of Covid-19 Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin-angiotensin-aldosterone inhibitors A rampage through the body Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study For 7 weeks I have been through a roller coaster of ill health, extreme emotions, and utter exhaustion Sex bias in referral of women to outpatient cardiac rehabilitation? In this article, the authors describe the most relevant knowledge thus far on sex differences regarding COVID-19.
    keywords: covid-19; differences; patients; sars; sex; virus
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        item: #4320 of 7819
          id: cord-309001-erm705tg
      author: Liu, Q.
       title: Laboratory findings and a combined multifactorial approach to predict death in critically ill patients with COVID-19: a retrospective study
        date: 2020-06-30
       words: 3457
      flesch: 48
     summary: (1) Combination of predictors and development of predictive model Three laboratory indicators were combined to provide a predictive probability value for the outcome of death in COVID-19 patients, which was expressed in terms of PRE. The cohort study from Jin Yin-tan Hospital and Wuhan Pulmonary Hospital (Wuhan, China) also found that DD greater than 1 μg/ml was the risk factor of death in COVID-19 patients.
    keywords: clinical; coronavirus; covid-19; death; disease; patients; study
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        item: #4321 of 7819
          id: cord-309024-pu830bn9
      author: Bernardo, Luca
       title: Severe prolonged neutropenia following administration of tocilizumab in a patient affected by COVID-19: a case report and brief review of the literature
        date: 2020-09-14
       words: 2963
      flesch: 35
     summary: Higher serum procalcitonin and IL-6 levels predict worse diagnosis for acute respiratory distress syndrome patients with multiple organ dysfunction Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China COVID-19: consider cytokine storm syndromes and immunosuppression Effective treatment of severe COVID-19 patients with tocilizumab A review of recent advances using tocilizumab in the treatment of rheumatic diseases Tocilizumab (Actemra) Efficacy and safety of tocilizumab in Korean patients with active rheumatoid arthritis Adverse effects of biologics: a network meta-analysis and Cochrane overview Longterm safety and efficacy of tocilizumab in patients with rheumatoid arthritis: a cumulative analysis of up to 4.6 years of exposure Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: a systematic literature review and meta-analysis of randomized controlled trials Tocilizumab-induced neutropenia in rheumatoid arthritis patients with previous history of neutropenia: case series and review of literature How to approach neutropenia Safety and efficacy profiles of tocilizumab monotherapy in Japanese patients with rheumatoid arthritis: meta-analysis of six initial trials and five long-term extensions Effect of tocilizumab on neutrophils in adult patients with rheumatoid arthritis: pooled analysis of data from phase 3 and 4 clinical trials Effects of tocilizumab on neutrophil function and kinetics Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: results from a single Italian Centre study on tocilizumab versus standard of care Tocilizumab for cytokine storm syndrome in COVID-19 pneumonia: an increased risk for candidemia? Chinese Clinical Trial Registry. • Black patients are more likely to have lower neutrophil counts than patients of other ethnicities due to a genetic predisposition.
    keywords: coronavirus; covid-19; infections; neutropenia; patients; tocilizumab
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        item: #4322 of 7819
          id: cord-309032-idjdzs97
      author: Zhou, Feng
       title: Epidemiological Characteristics and Factors Associated with Critical Time Intervals of COVID-19 in Eighteen Provinces, China: A Retrospective Study
        date: 2020-10-09
       words: 4177
      flesch: 44
     summary: Among the patients who were clearly exposed to confirmed cases, imported cases had more contacts with other confirmed cases than local cases on average, and contacts were mainly family members. Results Among 7,042 cases, 3392 (48.17%) were local cases and 3304 (46.92%) were imported cases.
    keywords: cases; characteristics; patients; time
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        item: #4323 of 7819
          id: cord-309080-1r8t8yxv
      author: Tay, Yi Xiang
       title: The needs and concerns of clinical educators in radiography education in the face of COVID-19 pandemic
        date: 2020-10-19
       words: 2533
      flesch: 31
     summary: During clinical training, students are supported by clinical educators who are usually registered professionals who facilitate clinical education alongside clinical and J o u r n a l P r e -p r o o f academic colleagues 8 . key: cord-309080-1r8t8yxv authors: Tay, Yi Xiang; Cai, Sihui; Chow, Hwei Chuin; Lai, Christopher title: The needs and concerns of clinical educators in radiography education in the face of COVID-19 pandemic date: 2020-10-19 journal: J Med Imaging Radiat Sci DOI: 10.1016/j.jmir.2020.10.004 sha: doc_id: 309080 cord_uid: 1r8t8yxv nan It has been more than 8 months since Singapore reported its first COVID-19 case on January 23 rd , 2020 1 .
    keywords: covid-19; education; educators; generation; pandemic; singapore; students
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        item: #4324 of 7819
          id: cord-309089-ex9nh1yi
      author: Coperchini, Francesca
       title: The Cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system
        date: 2020-05-11
       words: 6141
      flesch: 37
     summary: An interferon-gamma-related cytokine storm in SARS patients Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome Interaction of severe acute respiratory syndrome-associated coronavirus with dendritic cells Chemokine up-regulation in SARS-coronavirus-infected, monocyte-derived human dendritic cells Pathogenesis of severe acute respiratory syndrome Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome Induction of IL-8 release in lung cells via activator protein-1 by recombinant baculovirus displaying severe acute respiratory syndrome-coronavirus spike proteins: identification of two functional regions A human in vitro model system for investigating genome-wide host responses to SARS coronavirus infection Age-related increases in PGD(2) -Tumor necrosis factor α (TNFα) is a pyrogen cytokine released from immune cells in the acute phase of inflammation and infection.
    keywords: acute; cells; chemokines; coronavirus; cov; covid-19; cxcl10; cytokine; immune; infection; patients; sars; syndrome
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        item: #4325 of 7819
          id: cord-309095-ka9abe0c
      author: Idoiaga, Nahia
       title: Exploring Children’s Social and Emotional Representations of the COVID-19 Pandemic
        date: 2020-08-12
       words: 6401
      flesch: 51
     summary: Si se flexibiliza el estado de alarma, los niños deben ser los primeros en salir Nurses knowledge of growth and developmental principles in meeting psychosocial needs of hospitalized children Handbook of resilience in children HIV/ AIDS among adolescents in Eastern Europe: knowledge of HIV/AIDS, social representations of risk and sexual activity among school children and homeless adolescents in Russia, Georgia and the Ukraine España es el único país de Europa donde los niños no pueden salir de casa Health threats associated with children lockdown in Spain during COVID-19. Children were forbidden to leave their homes, with Spain along with Italy, being the only European countries where children were not allowed to go out at all (Granda, 2020; Grechyna, 2020) .
    keywords: analysis; children; coronavirus; covid-19; et al; lockdown; representations; research; social; years
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        item: #4326 of 7819
          id: cord-309125-ddgoc5yk
      author: Gavin, Blánaid
       title: Opportunities for international collaboration in COVID-19 mental health research
        date: 2020-06-16
       words: 1052
      flesch: 30
     summary: Moreover, the dearth of translational research relating to pandemic mental health science has resulted in extremely limited practical, real-world supports being quickly available to guide frontline staff. The implications for the current pandemic on mental health are numerous and complex.
    keywords: covid-19; health; pandemic; research
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        item: #4327 of 7819
          id: cord-309128-gmraihg6
      author: Yanai, Hidekatsu
       title: A Significance of High Prevalence of Diabetes and Hypertension in Severe COVID-19 Patients
        date: 2020-06-04
       words: 1430
      flesch: 41
     summary: Half of studies showed a statistically significantly higher prevalence of diabetes in severe patients than in non-severe patients. In the meta-analysis, the prevalence of diabetes in severe patients was significantly higher than that in non-severe patients (OR: 3.52, 95% CI: 2.65 -4.67).
    keywords: covid-19; diabetes; patients; prevalence
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        item: #4328 of 7819
          id: cord-309133-0jh84w6f
      author: Huang, Shiu-Feng
       title: Rapid establishment of a COVID-19 biobank in NHRI by National Biobank Consortium of Taiwan
        date: 2020-05-29
       words: 1978
      flesch: 56
     summary: Therefore, after Taiwan start to have COVID-19 patients in January, 2020, the Minister of Health and Welfare requested National Health Research Institutes (NHRI) to take the responsibility in coordinating the research in the treatment and prevention of COVID-19 infection in Taiwan. On Feb. 4, 2020, the 11 th COVID-19 case in Taiwan Following this request, an in-house expert panel meeting was immediately carried out on Feb.7, to discuss what kind of specimens to collect and what are the biosafety rules should be followed when collecting these specimens from COVID-19 patient.
    keywords: biobank; biosamples; covid-19; research; taiwan
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        item: #4329 of 7819
          id: cord-309134-mxk8d9jd
      author: Zhou, Yongxia
       title: Cohort study of chest CT and clinical changes in 29 patients with coronavirus disease 2019 (COVID-19)
        date: 2020-06-26
       words: 3757
      flesch: 51
     summary: key: cord-309134-mxk8d9jd authors: Zhou, Yongxia; Zheng, Yineng; Yang, Quan; Hu, Liangbo; Liao, Juan; Li, Xiaoyan title: Cohort study of chest CT and clinical changes in 29 patients with coronavirus disease 2019 (COVID-19) date: 2020-06-26 journal: Lung lesion development on chest CT reflects the clinical time course of COVID-19 progression over 1–6 days, followed by clinical improvement and the resorption of lesions.
    keywords: baseline; chest; covid-19; days; lesions; patients; time
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        item: #4330 of 7819
          id: cord-309138-44qpk2vf
      author: Khanna, Kanika
       title: Herbal Immune-boosters: Substantial Warriors of Pandemic Covid-19 Battle
        date: 2020-10-03
       words: 6407
      flesch: 25
     summary: Part I: Chemical diversity, impacts on plant biology and human health Antivirals against animal viruses Medicinal plants of Tamil Nadu (Southern India) are a rich source of antiviral activities Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Effect of Nilavembu kudineer in the Prevention and Management of COVID-19 by inhibiting ACE2 Receptor Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus The laboratory tests and host immunity of COVID-19 patients with different severity of illness Search of Preventative Strategies: Novel Anti-Inflammatory High-CBD Cannabis Sativa Extracts Modulate ACE2 Expression in COVID-19 Gateway Tissues Anti-influenza agents from plants and traditional Chinese medicine Adaptogens: Herbs for Strength. World Health Organization WHO guidelines on safety monitoring of herbal medicines in pharmacovigilance systems Evidence for Gastrointestinal Infection of SARS-CoV-2 Downregulation of Rac1 activation by caffeic acid in aortic smooth muscle cells Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Traditional Chinese medicine in the treatment of patients infected with 2019-new coronavirus (SARS-CoV-2): a review and perspective Herbs for Viral Respiratory Infections Herbal extracts as antiviral agents Water extract of licorice had anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines MERS, SARS and other coronaviruses as causes of pneumonia Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13 The traditional medicine and modern medicine from natural products COVID-19:
    keywords: activity; cells; coronavirus; cov-2; covid-19; et al; human; immune; infection; influenza; medicinal; novel; pak1; patients; plants; potential; sars; transmission
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        item: #4331 of 7819
          id: cord-309147-c3ikb81g
      author: Nadeem, Muhammad Shahid
       title: Origin, Potential Therapeutic Targets and Treatment for Coronavirus Disease (COVID-19)
        date: 2020-04-22
       words: 5006
      flesch: 43
     summary: A prospective study Influenza A virus shedding and infectivity in households Transmission of 2019-nCoV infection from an asymptomatic contact in Germany Structure, function, and evolution of coronavirus spike proteins Structure of SARS coronavirus spike receptor-binding domain complexed with receptor Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Severe acute respiratory syndrome Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis Mechanisms of host receptor adaptation by severe acute respiratory syndrome coronavirus Design of potent membrane fusion inhibitors against SARS-CoV-2, an emerging coronavirus with high fusogenic activity The novel coronavirus 2019 (COVID-19) uses the SARS-1 coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus: A first step in understanding SARS pathogenesis Potential interventions for novel coronavirus in China: A systematic review Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2 Cleavage and activation of the severe acute respiratory syndrome coronavirus spike protein by human airway trypsin-like protease Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike protein Coronaviruses post-SARS: Update on replication and pathogenesis Recent insights into emerging coronaviruses Therapeutic options for the 2019 novel coronavirus (2019-nCoV) Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics Preliminary identification of potential vaccine targets for the COVID-19 coronavirus (SARS-CoV-2) based on SARS-CoV immunological studies Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein Advances in respiratory virus therapeutics -A meeting report from the 6th isirv Antiviral Group conference Rapid Identification of Potential Inhibitors of SARS-CoV-2 Main Protease by Deep Docking of 1.3 Billion Compounds Identification of SARS-CoV-2 Cell Entry Inhibitors by Drug Repurposing Using in Silico Structure-Based Virtual Screening Approach WHO says vaccines against novel coronavirus 18 months away, pushes global research Can Chinese medicine be used for prevention of Corona virus disease 2019 (COVID-19)? Paving the Road for Rapid Detection and Point-of-Care Diagnostics Rapid colorimetric detection of COVID-19 coronavirus using a reverse tran-scriptional loop-mediated isothermal amplification (RT-LAMP) diagnostic plat-form: iLACO A Single and Two-Stage, Closed-Tube, Molecular Test for the 2019 Novel Coronavirus (COVID-19) at Home, Clinic, and Points of Entry Reverse transcription loop-mediated isothermal amplification combined with nanoparticles-based biosensor for diagnosis of COVID-19 Serological and molecular findings during SARS-CoV-2 infection: The first case study in Finland Molecular immune pathogenesis and diagnosis of COVID-19 A case of COVID-19 and pneumonia returning from Macau in Taiwan: Clinical course and anti-SARS-CoV-2 IgG dynamic Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: A single-centered, retrospective, observational study The SARS wake-up call Does SARS-CoV-2 has a longer incubation period than SARS and MERS? SARS-CoV infection in a restaurant from palm civet Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans Homologous recombination within the spike glycoprotein of the newly identified coronavirus may boost cross-species transmission from snake to human Host and infectivity prediction of Wuhan 2019 novel coronavirus using deep learning algorithm Real-time sequence-validated loop-mediated isothermal amplification assays for detection of Middle East respiratory syndrome coronavirus (MERS-CoV) Development and evaluation of novel real-time reverse transcription-PCR assays with locked nucleic acid probes targeting leader sequences of human-pathogenic coronaviruses COVID-19, an Emerging Coronavirus Infection: Current Scenario and Recent Developments-An Overview Pharmacologic treatment of SARS: Current knowledge and recommendations Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Of chloroquine and COVID-19 Chloroquine and hydroxychloroquine as available weapons to fight COVID-19 Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Temperature significant change COVID-19 Transmission in 429 cities 2019-Novel coronavirus (2019-nCoV):
    keywords: ace2; coronavirus; cov-2; covid-19; infection; novel; protease; protein; receptor; sars; spike
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        item: #4332 of 7819
          id: cord-309171-kgc7lgjp
      author: Dolinger, Michael T.
       title: Pediatric Crohn's Disease and Multisystem Inflammatory Syndrome in Children (MIS-C) and COVID-19 Treated with Infliximab
        date: 2020-05-21
       words: 1278
      flesch: 40
     summary: Management of Patients with Crohn's Disease and Ulcerative Colitis During the COVID-19 Pandemic: Results of an International Meeting Chemokine and cytokine levels in inflammatory bowel disease patients Increased production of tumour necrosis factor-alpha interleukin 1-beta, and interleukin 6 by morphologically normal intestinal biopsies from patients with Crohn's disease Clinical and immunological features of severe and moderate coronavirus disease 2019 Tocilizumab, an anti-IL6 receptor antibody, to treat COVID-19 related respiratory failure: a case report Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed but not TNF Antagonists, are Associated with Adverse COVID-19 Outcomes in Patients With Inflammatory Bowel Diseases: Results from an International Registry Inflammatory disease overlap possibly contributed to cytokine storm and MIS-C. Cytokine storm has been found to be a major cause of morbidity in patients with severe COVID-19 infection.
    keywords: covid-19; disease; tnf
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        item: #4333 of 7819
          id: cord-309194-jtouafgd
      author: Lu, Xiao
       title: Lung ultrasound score in establishing the timing of intubation in COVID-19 interstitial pneumonia: A preliminary retrospective observational study
        date: 2020-09-03
       words: 3673
      flesch: 40
     summary: Our study examined COVID-19 patients with interstitial pneumonia, using the clinical application of LUS to assess intubation timing. From February 14, 2020 to March 6, 2020, COVID-19 patients were admitted in the ICU of the Cancer Center of Union Hospital, Tongji Medical College, Huazhong University of Science and Technology.
    keywords: covid-19; intubation; lung; lus; patients; study; ultrasound
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        item: #4334 of 7819
          id: cord-309195-0scmephx
      author: Blicharz, Leszek
       title: Hand eczema ‐ a growing dermatological concern during the COVID‐19 pandemic and possible treatments
        date: 2020-05-08
       words: 576
      flesch: 44
     summary: The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak Hand eczema Hand eczema: epidemiology, prognosis and prevention Prevalence of, and work-related risk factors for, hand eczema in a Norwegian general population (The HUNT Study) Hand eczema: treatment Coronaviruses and immunosuppressed patients. key: cord-309195-0scmephx authors: Blicharz, Leszek; Czuwara, Joanna; Samochocki, Zbigniew; Goldust, Mohamad; Chrostowska, Sylwia; Olszewska, Małgorzata; Rudnicka, Lidia title: Hand eczema ‐ a growing dermatological concern during the COVID‐19 pandemic and possible treatments date: 2020-05-08 journal: Dermatol Ther DOI: 10.1111/dth.13545 sha: doc_id: 309195 cord_uid: 0scmephx nan Hand eczema (HE) is a relapsing and chronic condition of a heterogenous etiology.
    keywords: eczema; hand
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        item: #4335 of 7819
          id: cord-309200-t2xugb8l
      author: Asadi, Sima
       title: The coronavirus pandemic and aerosols: Does COVID-19 transmit via expiratory particles?
        date: 2020-04-03
       words: 2080
      flesch: 33
     summary: There is broad agreement in the infectious disease community about possible modes of respiratory virus transmission between humans (Tellier et al. 2019) . In fact long ago it was established that ordinary breathing and speech both emit large quantities of aerosol particles (Duguid 1946;
    keywords: aerosol; particles; transmission
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        item: #4336 of 7819
          id: cord-309214-v2iqgjc4
      author: Nougier, Christophe
       title: Hypofibrinolytic state and high thrombin generation may play a major role in sars‐cov2 associated thrombosis
        date: 2020-07-15
       words: 2632
      flesch: 35
     summary: Interestingly, ICU patients with thrombotic complications had a more thrombogenic TEM-tPA profile compared to Covid-19 patients without thrombosis ( Figure 1B) . The discrepancy between the frequency of thrombotic complications and the intensity of antithrombotic prophylaxis administered to Covid-19 patients is intriguing.
    keywords: covid-19; generation; icu; levels; patients; thrombin; thrombosis; tpa
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        item: #4337 of 7819
          id: cord-309236-p4c2d5y3
      author: Khurram, Ruhaid
       title: Spontaneous tension pneumothorax and acute pulmonary emboli in a patient with COVID-19 infection
        date: 2020-08-11
       words: 2414
      flesch: 35
     summary: World health organisation coronavirus disease (COVID-19) Dashboard Tension pneumothorax in a patient with COVID-19 Spontaneous pneumothorax and subcutaneous emphysema in COVID-19 patient: case report Spontaneous pneumomediastinum in COVID-19 COVID-19 with spontaneous pneumomediastinum SARS-CoV-2 pulmonary infection revealed by subcutaneous emphysema and pneumomediastinum COVID-19 with cystic features on computed tomography: a case report Acute pulmonary embolism in COVID-19 related hypercoagulability Severe pulmonary embolism in COVID-19 patients: a call for increased awareness Acute pulmonary embolism associated with COVID-19 pneumonia detected by pulmonary CT angiography Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Diagnostic performance of CT and reverse transcriptasepolymerase chain reaction for coronavirus disease 2019: Routine blood test results on admission were as follows: haemoglobin: 129 g/L; white cell count: 11.2×10 9 /L; platelets: 538×10 9 /L; neutrophils: Following initial management for the tension pneumothorax, a repeat chest radiograph demonstrated lung re-expansion with a small residual pneumothorax, but with no mediastinal shift; peripheral ground glass airspace opacities were accentuated, in keeping with COVID-19 infection (figure 2).
    keywords: case; chest; covid-19; oxygen; patient; pneumothorax
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        item: #4338 of 7819
          id: cord-309238-7lbt0f03
      author: Koratala, Abhilash
       title: Need for Objective Assessment of Volume Status in Critically Ill Patients with COVID-19: The Tri-POCUS Approach
        date: 2020-05-27
       words: 2777
      flesch: 33
     summary: In addition, LUS-derived aeration scores can be used to monitor response to therapy and for prognostication in COVID-19 patients with ARDS [19] . Moreover, FoCUS can be performed in COVID-19 patients undergoing prone ventilation, albeit with a minor modification in the image acquisition technique [22] .
    keywords: covid-19; fluid; management; patients; status; ultrasound; volume
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        item: #4339 of 7819
          id: cord-309267-ihc7h8ik
      author: Vervaecke, Deanna
       title: Caremongering and Assumptions of Need: The Spread of Compassionate Ageism During COVID-19
        date: 2020-09-12
       words: 4206
      flesch: 41
     summary: Paternalistic age stereotypes and assumptions of older adults competence that frame older people as dependent have homogenized older adults, cultivated the conditions of high risk A c c We begin by describing stereotype content theory and compassionate ageism and then explore how the oversimplification of COVID-19 risks for older adults has contributed to expressions of compassionate ageism.
    keywords: adults; ageism; caremongering; covid-19; pandemic
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        item: #4340 of 7819
          id: cord-309273-gtvi37gh
      author: Flesia, Luca
       title: Predicting Perceived Stress Related to the Covid-19 Outbreak through Stable Psychological Traits and Machine Learning Models
        date: 2020-10-19
       words: 7913
      flesch: 40
     summary: A more complete descriptive analysis of each variable, including the composition of high perceived stress versus low perceived stress samples, is reported in the Supplementary Materials. The effects of psychological stress on depression Chronic stress, hair cortisol and depression: A prospective and longitudinal study of medical internship Heightened biological stress response during exposure to a trauma film predicts an increase in intrusive memories A direct test of the diathesis-stress model for depression Psychological stress and coping in adaptation and illness Recommended psychological crisis intervention response to the 2019 novel coronavirus pneumonia outbreak in China: A model of West China Hospital.
    keywords: control; covid-19; data; health; levels; model; participants; people; score; self; stress; study; traits
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        item: #4341 of 7819
          id: cord-309302-n6cd2fc3
      author: Wang, Li
       title: Clinical management of lung cancer patients during the outbreak of COVID-19 epidemic
        date: 2020-09-23
       words: 5685
      flesch: 42
     summary: A study [43] analyzed 1590 patients with COVID-19 as of January 31, 2020, 18 (1%) had a history of cancer, 28% of cancer patient were lung cancer patients. key: cord-309302-n6cd2fc3 authors: Wang, Li; Jiang, Man; Qu, Jialin; Zhou, Na; Zhang, Xiaochun title: Clinical management of lung cancer patients during the outbreak of COVID-19 epidemic date: 2020-09-23 journal: Infect Agent Cancer DOI: 10.1186/s13027-020-00322-7 sha: doc_id: 309302 cord_uid: n6cd2fc3
    keywords: cancer; coronavirus; covid-19; epidemic; health; infection; lung; novel; patients; pneumonia; protein; sars; study; symptoms; treatment
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        item: #4342 of 7819
          id: cord-309315-3ojmmkwf
      author: Sugiyama, Yohsuke
       title: Cerebral venous thrombosis in COVID-19-associated coagulopathy: A case report
        date: 2020-07-23
       words: 1068
      flesch: 42
     summary: Monitoring coagulopathy is important in COVID-19 patients and in case of venous thromboembolism, including cerebral venous system, appropriate anticoagulant therapy should be initiated. [3] and the prevalence of headache was 13% in COVID-19 patients in Wuhan [6] .
    keywords: covid-19; cvt; patients
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        item: #4343 of 7819
          id: cord-309323-yflng8m3
      author: Thomas, T.
       title: COVID-19 infection results in alterations of the kynurenine pathway and fatty acid metabolism that correlate with IL-6 levels and renal status
        date: 2020-05-16
       words: 6967
      flesch: 31
     summary: The present study evaluated the serum metabolism of COVID-19 patients (n=33), identified by a positive nucleic acid test of a nasopharyngeal swab, as compared to COVID-19-negative control patients (n=16). Increased circulating levels of glucose and free fatty acids were also observed, consistent with altered carbon homeostasis in COVID-19 patients.
    keywords: acid; covid-19; figure; il-6; levels; medrxiv; medrxiv preprint; metabolism; patients; perpetuity; preprint; review; sars; subjects; version
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        item: #4344 of 7819
          id: cord-309333-lvcp8imi
      author: Fenichel, Eli P
       title: A cell phone data driven time use analysis of the COVID-19 epidemic
        date: 2020-04-23
       words: 5388
      flesch: 53
     summary: For counties not reporting epidemics we use the date that last county in the state first reported a case. . However, the right tail is inflated by rural counties where people may be spending more time alone (e.g., driving), but away from their homes and that have low device counts (see methods) and likely poor cell phone coverage.
    keywords: behavior; cases; counties; county; curve; data; epidemic; preprint; time
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        item: #4345 of 7819
          id: cord-309360-cpis1l4u
      author: Barrios-López, J. M.
       title: Ischaemic stroke and SARS-CoV-2 infection: A causal or incidental association?
        date: 2020-05-28
       words: 3155
      flesch: 35
     summary: Materials and methods We describe the cases of 4 patients with ischaemic stroke and COVID-19 who were attended at our hospital. We also conducted a review of studies addressing the possible mechanisms involved in the aetiopathogenesis of ischaemic stroke in these patients.
    keywords: causal; cov-2; covid-19; hypercoagulability; ictus; infection; inflammation; patients; sars; stroke; study
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        item: #4346 of 7819
          id: cord-309370-g8d3w7it
      author: Insausti-García, Alfredo
       title: Papillophlebitis in a COVID-19 patient: Inflammation and hypercoagulable state
        date: 2020-07-30
       words: 2087
      flesch: 34
     summary: Some studies have shown an incidence of venous and arterial thrombotic events in more than 30% of COVID-19 patients, with venous thromboembolic events being the most common (27%). Parallel to the alteration of coagulation, an exacerbated proinflammatory cytokines response has been observed in Covid-19 patients (CRP, Ferritin, IL-2, IL6, IL-7, IL-10, IP-10, TNFα, etc.), although the cause of this cytokine storm is not yet clear.
    keywords: covid-19; disease; edema; papillophlebitis; patients; sars
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        item: #4347 of 7819
          id: cord-309377-5pusd2pc
      author: Tran, Thi Phuong Thao
       title: Rapid response to the COVID-19 pandemic: Vietnam government’s experience and preliminary success
        date: 2020-07-28
       words: 6425
      flesch: 44
     summary: In March and April, a series of meetings among national senior officers were held to discuss health information and updates, as well as to share experiences on COVID-19 prevention, screening, and treatment across ASEAN countries [92] . Meetings among national senior officers were held in March and April to discuss and share country experiences on COVID-19 prevention, screening and treatment
    keywords: april; cases; control; countries; covid-19; decision; government; health; march; outbreak; pandemic; people; prevention; quarantine; vietnam
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        item: #4348 of 7819
          id: cord-309378-sfr1x0ob
      author: Röst, Gergely
       title: Early Phase of the COVID-19 Outbreak in Hungary and Post-Lockdown Scenarios
        date: 2020-06-30
       words: 10531
      flesch: 51
     summary: Benchmarking the CFR to other countries, we estimated underascertainment rate to be 10-20 times, and the true cumulative number of COVID-19 cases to be between 32,840 and 65,680. R Package Version 1.12.8 Shiny: Web Application Framework for R Real-Time Epidemiology of COVID-19 in Hungary (A Magyarországi Koronavírus jáRvány Valós Idejű Epidemiológiája-In Hungarian) Real-Time Epidemiology of COVID-19 in Hungary (A Magyarországi Koronavírus járváNy Valós Idejű A New Framework and Software to Estimate Time-Varying Reproduction Numbers During Epidemics Different Epidemic Curves for Severe Acute Respiratory Syndrome Reveal Similar Impacts of Control Measures How Generation Intervals Shape the Relationship Between Growth Rates and Reproductive Numbers The Effective Reproduction Number of Pandemic Influenza: Prospective Estimation Association of Public Health Interventions With the Epidemiology of the COVID-19 Outbreak in Wuhan Effective Reproduction Number Estimation Estimating in real time the efficacy of measures to control emerging communicable diseases Serial Interval of COVID-19 Among Publicly Reported Confirmed Cases Epidemiological characteristics of COVID-19 cases in Italy and estimates of the reproductive numbers one month into the epidemic Serial interval of novel coronavirus (COVID-19) infections The R0 package: A toolbox to estimate reproduction numbers for epidemic outbreaks R0: Estimation of R0 and Real-Time Reproduction Number from Epidemics.
    keywords: age; cases; contact; control; covid-19; disease; epidemic; figure; model; number; peak; population; reproduction; time; transmission
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        item: #4349 of 7819
          id: cord-309395-5yan9fcn
      author: Kazory, Amir
       title: SARS-CoV-2 (COVID-19) and intravascular volume management strategies in the critically ill
        date: 2020-04-16
       words: 3775
      flesch: 30
     summary: Constantly reminding ourselves of the currently available evidence on fluid resuscitation strategies, and judiciously applying those principles to the specific features of this disease as we learn them (e.g., high percentage of heart failure, volume overload, and circulatory failure), is likely to help optimize the care of these patients. However, Liu et al showed that after correcting serum creatinine levels for fluid balance, the incidence of AKI was lower with a restrictive fluid strategy.
    keywords: acute; covid-19; failure; fluid; management; patients; sepsis; shock
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        item: #4350 of 7819
          id: cord-309418-dx6e0lri
      author: Segalés, Joaquim
       title: Detection of SARS-CoV-2 in a cat owned by a COVID-19−affected patient in Spain
        date: 2020-10-06
       words: 3140
      flesch: 40
     summary: Although the exact moment of exposure or infection was not possible to determine based on the reconstruction of the chronological events around the present case (Fig. 2) , the low amount of SARS-CoV-2 (Ct values of >32) found in positive samples of C1, evidence of SARS-CoV-2 seroconversion, the lack of compatible lesions with a viral disease, and the preexisting morbid conditions suggest that SARS-CoV-2 infection in C1 was an incidental epidemiological finding. A pneumonia outbreak associated with a new coronavirus of probable bat origin The proximal origin of SARS-CoV-2 The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice Transmission of SARS-CoV-2 in domestic cats Infection and rapid transmission of SARS-CoV-2 in ferrets Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2 Age-related rhesus macaque models of COVID-19 Infection of dogs with SARS-CoV-2 SARS-CoV2 infection in farmed mink Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Feline hypertrophic cardiomyopathy: An update Search for SARS-CoV-2 inhibitors in currently approved drugs to tackle COVID-19 pandemia Cutadapt removes adapter sequences from high-throughput sequencing reads PEAR:
    keywords: animal; cat; cats; cov-2; covid-19; infection; nasal; sars
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        item: #4351 of 7819
          id: cord-309436-5qoo3a8i
      author: Balanzá–Martínez, V.
       title: Lifestyle behaviours during the COVID‐19 – time to connect
        date: 2020-05-12
       words: 1002
      flesch: 38
     summary: V. Balanz a-Mart ınez 1, 2 , B. Atienza-Carbonell 3 , F. Kapczinski 4 , R. B. De Boni 6 Social isolation, loneliness and health in old age: a scoping review An overview of systematic reviews on the public health consequences of social isolation and loneliness Combined impact of healthy lifestyle factors on lifespan: two prospective cohorts Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illness International Society for Nutritional Psychiatry Research. From public health and preventative care perspectives, there is a pressing need to provide individuals, communities and health agencies with information and interventions to maintain the healthiest possible lifestyle while in isolation.
    keywords: covid-19; health; lifestyle; public
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        item: #4352 of 7819
          id: cord-309441-obojsf04
      author: Pirau, Letitia
       title: Case Series: Evidence of Borderzone Ischemia in Critically-Ill COVID-19 Patients Who “Do Not Wake Up”
        date: 2020-09-23
       words: 2748
      flesch: 31
     summary: An important problem encountered in the care of COVID-19 patients who require intubation for ARDS and acute hypoxic respiratory failure is prolonged unresponsiveness following discontinuation of sedation (7) . A pro-thrombotic state is well-documented in COVID-19 patients (10, 11) .
    keywords: admission; covid-19; days; injury; patients; sedation
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        item: #4353 of 7819
          id: cord-309478-yhmgopmr
      author: Jin, Ying-Hui
       title: Perceived infection transmission routes, infection control practices, psychosocial changes, and management of COVID-19 infected healthcare workers in a tertiary acute care hospital in Wuhan: a cross-sectional survey
        date: 2020-05-11
       words: 4565
      flesch: 45
     summary: Hence, this study aims to explore perceived infection routes, influencing factors, psychosocial changes, and management procedures for COVID-19 infected healthcare workers. key: cord-309478-yhmgopmr authors: Jin, Ying-Hui; Huang, Qiao; Wang, Yun-Yun; Zeng, Xian-Tao; Luo, Li-Sha; Pan, Zhen-Yu; Yuan, Yu-Feng; Chen, Zhi-Min; Cheng, Zhen-Shun; Huang, Xing; Wang, Na; Li, Bing-Hui; Zi, Hao; Zhao, Ming-Juan; Ma, Lin-Lu; Deng, Tong; Wang, Ying; Wang, Xing-Huan title: Perceived infection transmission routes, infection control practices, psychosocial changes, and management of COVID-19 infected healthcare workers in a tertiary acute care hospital in Wuhan: a cross-sectional survey date: 2020-05-11 journal:
    keywords: cases; covid-19; equipment; healthcare; hospital; infection; patients; staff; study; workers
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        item: #4354 of 7819
          id: cord-309482-frawgvk7
      author: Cook, T. M.
       title: Kicking on while it’s still kicking off – getting surgery and anaesthesia restarted after COVID‐19
        date: 2020-06-01
       words: 2673
      flesch: 45
     summary: Repatriation of these key elements to their proper places in peri-operative pathways is a prerequisite to any return to pre-pandemic levels of planned surgery. However, waiting for 3 months may underestimate the reality, and non-urgent surgery may be delayed much longer.
    keywords: care; covid-19; need; pandemic; patients; staff; surgery
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        item: #4355 of 7819
          id: cord-309509-ftwpys3y
      author: Ondoa, Pascale
       title: COVID-19 testing in Africa: lessons learnt
        date: 2020-07-03
       words: 1108
      flesch: 31
     summary: To address these challenges, Africa CDC launched the Partnership to Accelerate COVID-19 Testing on request from AU heads of states, with the following key strategic areas: (1) organising all AU member states as one large customer and coordinating the continuous supply of test kits and commodities at a negotiated price and based on accurate forecast of needs; (2) decentralising COVID-19 testing through strategic planning that can guarantee laboratory quality, biosafety, and the establishment of robust sample referral systems; e104 www.thelancet.com/microbe key: cord-309509-ftwpys3y authors: Ondoa, Pascale; Kebede, Yenew; Loembe, Marguerite Massinga; Bhiman, Jinal N; Tessema, Sofonias Kifle; Sow, Abdourahmane; Sall, Amadou Alpha; Nkengasong, John title: COVID-19 testing in Africa: lessons learnt date: 2020-07-03 journal: Lancet Microbe DOI: 10.1016/s2666-5247(20)30068-9 sha: doc_id: 309509 cord_uid: ftwpys3y nan www.thelancet.com/microbe
    keywords: africa; capacity; covid-19; laboratory; testing
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        item: #4356 of 7819
          id: cord-309521-2cb992u1
      author: Iqbal, Muhammad Rafaih
       title: “COVID-19: Results of a national survey of United Kingdom healthcare professionals’ perceptions of current management strategy – a cross-sectional questionnaire study”
        date: 2020-05-21
       words: 3043
      flesch: 53
     summary: Two-third of the respondents (n=665, 66.03%) did not think that adequate PPE were available to the frontline staff. A third of the respondents from Scotland (32.43%) thought adequate PPE was not available while in other regions nearly two-third of the respondents were not happy with the availability of PPE (Northern Ireland: 61.53%, England: 68.11%, Wales: 77.14%).
    keywords: covid-19; hcps; health; pandemic; ppe; respondents; survey
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        item: #4357 of 7819
          id: cord-309571-a0xu1d56
      author: Aboughdir, Maryam
       title: Prognostic Value of Cardiovascular Biomarkers in COVID-19: A Review
        date: 2020-05-11
       words: 5692
      flesch: 42
     summary: Although COVID-19 patients present primarily with symptoms of respiratory disease and therefore follow a pneumonia-like treatment plan, it is essential that the cardiovascular system is not ignored and to recognise those presenting with early signs of acute myocardial injury. Additionally, Zhou et al. found that myocardial injury, defined by raised serum cardiac troponin I (cTnI) levels, in COVID-19 patients was associated with over 50% mortality rate [12] .
    keywords: angiotensin; covid-19; ctni; injury; levels; mortality; patients; risk
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        item: #4358 of 7819
          id: cord-309582-ihrj84hr
      author: AlNaamani, Khalid
       title: Medical research during the COVID-19 pandemic
        date: 2020-08-06
       words: 4052
      flesch: 31
     summary: However, these clinical trials may require modifications due a pandemic such as this one to ensure the rights, safety, and wellbeing of participants as well as medical staff involved in the conduction of clinical trials. Clinical trials initiated during the pandemic must be time-efficient and flexible due to high contagiousness of severe acute respiratory syndrome coronavirus 2, the significant number of reported deaths, and time constraints needed to perform high quality clinical trials, enrolling adequate sample sizes.
    keywords: coronavirus; cov-2; covid-19; pandemic; patients; research; sars; time; trials
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        item: #4359 of 7819
          id: cord-309590-8p7qp4it
      author: Anacak, Yavuz
       title: Changes in radiotherapy practice during COVID–19 outbreak in turkey: a report from the turkish society for radiation oncology
        date: 2020-06-13
       words: 1122
      flesch: 29
     summary: Several administrative changes were done in radiotherapy departments to prevent COVID-19 spread; these included the usage of face masks, gowns and gloves for all personnel, disinfection of treatment machines and equipment after every patient, providing social distancing measures, reducing the number of people in the department, and educating patients about COVID-19 disease and cancer. Turkish Society for Radiation Oncology (TROD) immediately involved in the events upon the arrival of the virus to Turkey and collaborated with MoH. TROD informed its members with regular announcements, produced guidelines for management of radiotherapy departments and recommendations for site-specific treatment modifications, and prepared a document to inform cancer patients about the do's and don'ts during the pandemic.
    keywords: covid-19; departments; patients; radiotherapy
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        item: #4360 of 7819
          id: cord-309608-oal60som
      author: Luo, Shihua
       title: Don't Overlook Digestive Symptoms in Patients With 2019 Novel Coronavirus Disease (COVID-19)
        date: 2020-03-20
       words: 914
      flesch: 56
     summary: 3 Of 1141 confirmed COVID-19 cases, 183 (16%) presented with gastrointestinal symptoms only, and their clinical characteristics are summarized in Table 1 . Our case series shows that some patients can present with gastrointestinal symptoms, with a paucity of other manifestations.
    keywords: covid-19; patients; symptoms
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        item: #4361 of 7819
          id: cord-309619-glb2y82u
      author: Domingo, Pere
       title: The four horsemen of a viral Apocalypse: The pathogenesis of SARS-CoV-2 infection (COVID-19)
        date: 2020-07-29
       words: 9372
      flesch: 35
     summary: Front Immunol 2020 Relationships among lymphocyte subsets, cytokines, and the pulmonary inflammation index in coronavirus (COVID-19) infected patients Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Cellular inhibitor of apoptosis protein cIAP2 protects against pulmonary tissue necrosis during influenza virus infection to promote host survival T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice Adaptive immune cells temper initial innate responses Clinical characteristics of coronavirus disease 2019 in China Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients Middle east respiratory syndrome coronavirus (MERS-CoV): infection, immunological response, and vaccine development Bcl-xL inhibits T-cell apoptosis induced by expression of SARS coronavirus E protein in the absence of growth factors SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion Cell pyroptosis, a potential pathogenic mechanism of 2019-nCoV Infection (2020) Severe acute respiratory syndrome coronavirus Viroporin 3a activates the NLRP3 inflammasome Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study Antibody responses against SARS coronavirus are correlated with disease outcome of infected individuals The potential danger of suboptimal antibody responses in COVID-19 The ACE2/Angiotensin-(1-7)/MAS axis of the renin-angiotensin system: focus on angiotensin Kidneys and fluids in pressure regulation. COVID-19 patients have high serum levels of inflammatory cytokines, including interleukin (IL)-2, IL-7, IL-10, granulocyte-colony stimulating factor (G-CSF), interferon gamma-induced protein (IP)-10, monocyte chemoattractant protein (MCP)-1, macrophage SARS-CoV-2 infects primarily type II pneumocytes through binding to the ACE2 receptor.
    keywords: ace2; acute; angiotensin; cells; converting; coronavirus; cov-2; covid-19; disease; expression; immune; infection; inflammatory; lung; patients; protein; receptor; response; role; sars; syndrome
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        item: #4362 of 7819
          id: cord-309629-7jtnhn65
      author: Thomas, Viju
       title: International society for gynecologic endoscopy (ISGE) guidelines and recommendations on gynecological endoscopy during the evolutionary phases of the SARS-CoV-2 pandemic
        date: 2020-08-26
       words: 4634
      flesch: 44
     summary: Currently we need to balance a hypothetical risk of aerosol spread in low risk patients to the vast array of evidence proving the benefits of laparoscopic surgery. Patients who screen or test negative may have general anesthesia and laparoscopic surgery while strict protocols of infection control are upheld.
    keywords: cov-2; covid-19; gas; laparoscopy; patients; risk; sars; smoke; surgery
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        item: #4363 of 7819
          id: cord-309644-cujlpm4i
      author: Sola, Augusto
       title: COVID-19 perinatal en América Latina
        date: 2020-07-31
       words: 3059
      flesch: 48
     summary: Son preocupantes la falta de acompañamiento materno, la baja tasa de lactancia y la frecuente separación de la díada madre-hijo. Hoy más que nunca resulta imperioso sostener recomendaciones específicas para asignar los recursos sanitarios de una manera justa, lo que incluye maximizar los beneficios de las prácticas que se saben efectivas, cuidar la salud de los trabajadores, aplicar la evidencia y colaborar con su construcción a través del reporte de datos, y siempre aplicar los mismos principios éticos para el cuidado de los niños y las madres con COVID-19 20 y sin ella.
    keywords: casos; con; cov-2; covid-19; del; embarazadas; fue; las; los; madre; para; pcr; perinatal; por; que; sars
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        item: #4364 of 7819
          id: cord-309650-6xz9gjq0
      author: Chou, Roger
       title: Update Alert 4: Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers
        date: 2020-09-11
       words: 1475
      flesch: -237
     summary: Female vs. male (IgG): OR, 0.58 (0.20-1.67) IgG: 14.8% (7/115) IgG: 7.8% (5/64) Nurse vs /105) Nurse vs. physician: OR, 0.49 (0.15-1.55) Radiology technician: 29.4% (5/17) Other HCW role: 2.4% (1/41) 29 y: 2.3% (2/88) Epidemiology of and risk factors for coronavirus infection in health care workers Update Alert 2: Epidemiology of and risk factors for coronavirus infection in health care workers Low seroprevalence of SARS-CoV-2 infection among healthcare workers of the largest children hospital in Milan during the pandemic wave Efficacy of a test-retest strategy in residents and health care personnel of a nursing home facing a COVID-19 outbreak Large-scale, molecular and serological SARS-CoV-2 screening of healthcare workers in a 4-site public hospital in Belgium after COVID-19 outbreak Specific risk factors for SARS-CoV-2 transmission among health care workers in a university hospital Seroprevalence of SARS-CoV-2 antibodies in healthcare workers at a London NHS Trust Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Seroprevalence of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) antibodies among healthcare workers with differing levels of coronavirus disease 2019 (COVID-19) patient exposure Prevalence of SARS-CoV-2 infection among health care workers in a tertiary community hospital SARS-CoV-2 infection among healthcare workers of a gastroenterological service in a tertiary care facility Infection with SARS-CoV-2 in primary care health care workers assessed by antibody testing Prevalence of SARS-CoV-2 antibodies in health care personnel in the New York City area Search for asymptomatic carriers of SARS-CoV-2 in healthcare workers during the pandemic: a Spanish experience COVID-19 outbreak in healthcare workers in Trieste hospitals SARS-CoV-2 specific serological pattern in healthcare workers of an Italian COVID-19 forefront hospital COVID-19 screening for healthcare workers in a tertiary infectious diseases referral hospital in Manila, the Philippines The role of isolation rooms, facemasks and intensified hand hygiene in the prevention of nosocomial COVID-19 transmission in a pulmonary clinical setting Asymptomatic infection by SARS-CoV-2 in healthcare workers: a study in a large teaching hospital in Wuhan, China Update Alert: epidemiology of and risk factors for coronavirus infection in health care workers Update Alert 3: epidemiology of and risk factors for coronavirus infection in health care workers Risks to healthcare workers following tracheal intubation of patients with COVID-19: a prospective international multicentre cohort study SARS-CoV-2 infection in healthcare personnel with highrisk occupational exposure: evaluation of seven-day exclusion from work policy Dynamic of SARS-CoV-2 RT-PCR positivity and seroprevalence among high-risk health care workers and hospital staff Occupation and risk of COVID-19: prospective cohort study of 120,621 UK Biobank participants Risk of COVID-19 among frontline healthcare workers and the general community: a prospective cohort study. The Lancet Prevalence of serum IgG antibodies against SARS-CoV-2 among clinic staff SARS-CoV-2 infection in health care workers: a retrospective analysis and a model study COVID-19 infections among healthcare workers exposed to a patient with a delayed diagnosis of COVID-19 Containment of a traceable COVID-19 outbreak among healthcare workers at a hematopoietic stem cell transplantation unit SARS-CoV-2 infection in health care Transmission of COVID-19 to health care personnel during exposures to a hospitalized patient COVID-19 screening of health-care workers in a London maternity hospital COVID-2019) infection among health care workers and implications for prevention measures in a tertiary hospital in Wuhan, China Epidemiological,clinical and radiological findings in medical staff with COVID-19 in Wuhan, China: a single-centered Prevention and protection measures of healthcare workers exposed in health settings to severe acute respiratory infections from SARS-CoV-2 in a univeristy hospital in Bari, Apulia Region, southern Italy Occupational exposures and programmatic response to COVID-19 pandemic: an emergency medical services experience Risk factors of healthcare workers with Corona Virus Disease 2019: a retrospective cohort study in a designated hospital of Wuhan in China COVID-19: PCR screening of asymptomatic health-care workers at London hospital Epidemiological characteristics of COVID-19 in medical staff members of neurosurgery departments in Hubei province: A multicentre descriptive study Investigation of nosocomial SARS-CoV-2 transmission from two patients to health care workers identifies close contact but not airborne transmission events Symptom criteria for COVID-19 testing of health care workers Psychological impact of the coronavirus disease 2019 (COVID-19) outbreak on healthcare workers in China Impact of COVID-19 outbreak on healthcare workers in Italy: results from a national e-survey Report of 5 nurses infecting COVID-19 during patient care: case Series Impact on mental health and perceptions of psychological care among medical and nursing staff in Wuhan during the 2019 Novel Coronavirus Disease outbreak: a cross-sectional study Prevalence and clinical presentation of health care workers with symptoms of coronavirus disease 2019 in 2 Dutch hospitals during an early phase of the pandemic SARS-CoV-2-specific antibody detection in healthcare workers in Germany with direct contact to COVID-19 patients Prevalence of SARS-CoV-2 infection in health workers (HWs) and diagnostic test performance: the experience of a teaching hospital in Central Italy The prevalence and influencing factors for anxiety in medical workers fighting COVID-19 in China: A cross-sectional survey Characteristics of 1,573 healthcare workers who underwent nasopharyngeal swab for SARS-CoV-2 in Milano Impact of the COVID-19 pandemic on Gastroenterology Divisions in Italy: a national survey COVID-19 mortality in Italian doctors Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission COVID-19 Psychological impact in 3109 healthcare workers in Spain: The PSIMCOV Group Outbreak investigation of COVID-19 among residents and staff of an independent and assisted living community for older adults in SARS-CoV-2 seroconversion in health care workers COVID-19 in healthcare workers in three hospitals in the South of the Netherlands Serological prevalence of antibodies to SARS CoV-2 amongst cancer centre staff Comparing hospitalised, community and staff COVID-19 infection rates during the early phase of the evolving COVID-19 epidemic COVID-19 cluster study at a teaching hospital At the height of the storm: Healthcare staff's health conditions and job satisfaction and their associated predictors during the epidemic peak of COVID-19 Analysis of the infection status of the health care workers in Wuhan during the COVID-19 outbreak: A cross-sectional study COVID-19 in Wuhan: immediate psychological impact on 5062 health workers Deaths from COVID-19 in healthcare workers in Italy -what can we learn?
    keywords: care; covid-19; health; healthcare; infection; workers
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        item: #4365 of 7819
          id: cord-309668-5rytk13w
      author: Alsini, Albaraa Y.
       title: Tongue reconstruction post partial glossectomy during the COVID-19 pandemic. A case report
        date: 2020-09-06
       words: 3283
      flesch: 48
     summary: We present two cases of tongue reconstruction with acellular dermal matrix post partial glossectomy for tongue carcinoma during the COVID-19 pandemic. Case presentation: We present two cases of tongue reconstruction with acellular dermal matrix post partial glossectomy for tongue carcinoma during the COVID-19 pandemic.
    keywords: adm; case; covid-19; oral; patient; reconstruction; report; tongue
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        item: #4366 of 7819
          id: cord-309705-el5rembl
      author: Dantés, Héctor Gómez
       title: Prevention and control of Aedes transmitted infections in the post-pandemic scenario of COVID-19: challenges and opportunities for the region of the Americas
        date: 2020-08-05
       words: 2690
      flesch: 25
     summary: Novel coronavirus (2019-nCoV) Situation Report -1; 21 Coronavirus disease 2019 (COVID-19) Situation Report -77 Impact of international travel and border control measures on the global spread of the novel 2019 coronavirus outbreak Estimation of the probability of reinfection with COVID-19 by the susceptible-exposed-infectious-removedundetectable-susceptible model Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period Situación de COVID-19 en la región de las Américas Covid in Latin America COVID-19 and dengue fever: a dangerous combination for the health system in Brazil COVID-19 and dengue, co-epidemics in Ecuador and other countries in Latin America: pushing strained health care systems over the edge PAHO/WHO -Pan American Health Organization/World Health Organization. Health information platform for the Americas (PLISA, PAHO/WHO), accessed on 26 To alert coinfection of COVID-19 and dengue virus in developing countries in the dengue-endemic area COVID-19 and dengue, co-epidemics in Ecuador and other countries in Latin America: pushing strained health care systems over the edge The neglected tropical diseases of Latin America and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination Economic impact of dengue illness in the Americas Gender mainstreaming as a pathway for sustainable arbovirus control in Latin America Technical document for the implementation of interventions based on generic operational scenarios for Aedes aegypti control Evaluación de las estrategias innovadoras para el control de Aedes aegypti: desafíos para su introducción y evaluación del impacto Manual para aplicar rociado residual intradomiciliario en zonas urbanas para el control de Aedes aegypti Combining contact tracing with targeted indoor residual spraying significantly reduces dengue transmission Efficacy of novel indoor residual spraying methods targeting pyrethroid-resistant Aedes aegypti within experimental houses Estrategia de control de vectores en el escenario de transmisión simultánea dengue y COVID-19 en México Plan de acción sobre entomologia y control de vectores 2018-2023
    keywords: care; control; countries; covid-19; dengue; diseases; health; transmission
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        item: #4367 of 7819
          id: cord-309706-kikx05dj
      author: MacDonald, Scott
       title: Implementing a 2019 coronavirus disease airway management strategy for a provincial critical care and ground transport program
        date: 2020-06-03
       words: 1556
      flesch: 38
     summary: As an example, the NS provincial strategy for airway management for COVID-19 patients highlights a combined effort of many moving parts culminating in a cohesive plan to manage and transport the sickest patients in the province. LifeFlight had to ensure that they could safely apply these hospital-based recommendations around airway management for COVID-19 patients. EHS, working closely with other clinical leaders within the health authority, used this resource document as a springboard to inform changes to usual practice related to COVID-19.
    keywords: airway; care; covid-19; management; patients
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        item: #4368 of 7819
          id: cord-309711-x07odyxl
      author: Pereyra, David
       title: Routine haematological parameters in COVID-19 prognosis
        date: 2020-09-22
       words: 626
      flesch: 44
     summary: In line with previous studies, coagulation parameters were deranged in patients with severe or fatal COVID-19, with D-dimer concentrations being significantly elevated, prompting their use as a biomarker for patient outcome. Thrombocytopenia at admission (platelet count <100 x 10 cells per L) was not more prevalent in patients with fatal outcome (4%) than in patients with a non-fatal outcome (7%; odds ratio
    keywords: covid-19; patients
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        item: #4369 of 7819
          id: cord-309716-4wn3lx70
      author: Wang, W.
       title: Thyroid function abnormalities in COVID-19 patients
        date: 2020-06-16
       words: 3169
      flesch: 50
     summary: Methods: 84 hospitalized COVID-19 patients in the First Affiliated Hospital, Zhejiang University School of Medicine (Hangzhou, China) were respectively enrolled in this study. We found that the levels of TT3 and TSH were lower in COVID-19 patients than control groups (p<0.001).
    keywords: covid-19; license; patients; preprint; thyroid; tsh
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        item: #4370 of 7819
          id: cord-309728-7vfotgrr
      author: Johnson, Kristen M.
       title: Managing COVID‐19 in Renal Transplant Recipients: A Review of Recent Literature and Case Supporting Corticosteroid‐sparing Immunosuppression
        date: 2020-05-26
       words: 3206
      flesch: 31
     summary: Very little data are currently available regarding the optimal medical management of renal transplant patients testing positive for SARS-CoV-2 including strategies for reducing or modifying immunosuppression. The authors cited that the use of corticosteroids to maintain immunosuppression in these patients likely increased the risk for these infections and warrants caution with the use of corticosteroids in maintaining immunosuppression for transplant patients with SARS-CoV-2.
    keywords: cov-2; day; disease; immunosuppression; patients; recipients; sars; transplant
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        item: #4371 of 7819
          id: cord-309729-nd48uh8e
      author: Antunes, Adriane E.C.
       title: Potential contribution of beneficial microbes to face the COVID- 19 pandemic
        date: 2020-07-24
       words: 4849
      flesch: 27
     summary: Journal of Cystic Fibrosis, 16 (2) Gou, W., Fu, Y., Yue, L., Chen, G., Cai, X., Shuai, M., Xu, F., Yi, X., Chen, H Graphical abstract Diet, microbiota and gut-lung connection Effect of probiotics on respiratory, gastrointestinal and nutritional outcomes in patients with cystic fibrosis: a systematic The microbiota protects against respiratory infection via GM-CSF signaling An age dependent pharyngeal microbiota signature associated with SARS-CoV-2 infection Clinical characteristics of 5 COVID-19 cases with non-respiratory symptoms as the first manifestation in children Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Coronavirus Diseases 2019 (COVID-19) Treatment Guidelines The microbiota-gut-brain axis Probiotics for preventing acute upper respiratory tract infections ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation Dietary fiber and prebiotics and the gastrointestinal microbiota Clinical features of patients infected with 2019 novel coronavirus in Diet supplementation, probiotics, and nutraceuticals in SARS-CoV-2 infection: a scoping review Two things about COVID-19 might need attention Specific probiotics and virological findings in symptomatic conscrips attending military service in Finland Public health and budget impact of probiotics on common respiratory tract infections: a modelling study The clinical and economic impact of probiotics consumption on respiratory tract infections: projections for Canada Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia Effects of Bifidobacterium longum BB536 administration on influenza infection, influenza vaccine antibody titer, and cell-mediated immunity in the elderly A randomized synbiotic trial to prevent sepsis among infants in rural India Specific probiotics in reducing the risk of acute infections in infancy-a randomised, double-blind, placebo-controlled study Probiotics: reiterating what they are and what they are not ACE2 at the centre of COVID-19 from paucisymptomatic infections to severe pneumonia Gut microbiota, metabolites and host immunity Milk kefir: nutritional, microbiological and health benefits The effect of probiotics for preventing acute upper respiratory tract infections Probiotics, gut microbiota, and their influence on host health and disease The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia Synbiotics modulate gut microbiota and reduce enteritis and ventilator-associated pneumonia in patients with sepsis: a randomized controlled trial Vulnerability of the industrialized microbiota Probiotics for the prevention of ventilatorassociated pneumonia: a meta-analysis of randomized controlled trials Evaluation of the probiotic Lactobacillus coryniformis K8 on COVID-19 prevention in healthcare workers (Clinical Trial gov Identifier NCT04366180, 2020) Oxygen-ozone as adjuvant treatment in early control of COVID-19 progression and modulation of the gut microbial flora (PROBIOZOVID) (Clinical Trial gov Identifier NCT04366089, 2020) Probiotics for the prevention of respiratory tract infections: a systematic review Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: a double blind, randomized, controlled trial Effects of probiotic Lactobacillus brevis KB290 on incidence of influenza infection among schoolchildren: an open-label pilot study Review of the 2019 novel coronavirus (SARS-CoV-2) based on current evidence Probiotics for prevention and treatment of respiratory tract infections in children: a systematic review and meta-analysis of randomized controlled trials Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected: interim guidance A new coronavirus associated with human respiratory disease in China High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa Management of COVID-19: the Zhejiang experience Exuberant elevation of IP-10, MCP-3 and IL-1ra during 902 SARS-CoV-2 infection is associated with disease severity and fatal outcome MERS, SARS and other coronaviruses as causes of pneumonia
    keywords: coronavirus; cov-2; covid-19; et al; foods; gut; immunity; infection; microbiota; probiotics; sars; symptoms
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        item: #4372 of 7819
          id: cord-309733-x4crng5j
      author: Dhesi, Z.
       title: Organisms causing secondary pneumonias in COVID-19 patients at 5 UK ICUs as detected with the FilmArray test
        date: 2020-06-23
       words: 3633
      flesch: 37
     summary: FilmArray test results and clinical microbiology results were recorded, along with a brief statement of the reason for FilmArray testing. Accordingly, we aimed to define the bacteria causing secondary pneumonias in COVID-19 ICU patients using the FilmArray Pneumonia Panel, and to determine this tests potential in COVID-19 management.
    keywords: covid-19; filmarray; license; patients; pneumonia; preprint; results
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        item: #4373 of 7819
          id: cord-309739-3smgv1ma
      author: Doyle, Andrew J
       title: Blood Component Use in Critical Care in Patients with COVID‐19 Infection: A Single Centre Experience
        date: 2020-07-08
       words: 1487
      flesch: 41
     summary: Despite the increased demands of healthcare resources at the time of the COVID-19 pandemic, it appears that the infection itself does not cause a significant increase in blood component use in comparison to previous data from critical care (Chohan et al, 2003) . At present, the demands on blood components have not been described.
    keywords: blood; care; patients
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        item: #4374 of 7819
          id: cord-309751-7elnvjk3
      author: Abdelnasser, Mohammad Kamal
       title: COVID-19. An update for orthopedic surgeons
        date: 2020-07-01
       words: 5223
      flesch: 45
     summary: Managing COVID-19 patients with surgical emergencies and trauma with the risk of self-infection have led to a higher degree of anxiety and depression [32] . Suspected or confirmed COVID-19 patients should be isolated in a separate room and should keep at least 6 feet distance from other patients or non-treating staff.
    keywords: care; covid-19; elective; infection; operating; orthopedic; pandemic; patients; practice; room; surgery; training; trauma
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        item: #4375 of 7819
          id: cord-309769-phi3re5g
      author: Weissman, Ruth Striegel
       title: Conducting eating disorders research in the time of COVID‐19: A survey of researchers in the field
        date: 2020-05-25
       words: 5375
      flesch: 36
     summary: key: cord-309769-phi3re5g authors: Weissman, Ruth Striegel; Klump, Kelly L.; Rose, Jennifer title: Conducting eating disorders research in the time of COVID‐19: A survey of researchers in the field date: 2020-05-25 journal: Int J Eat Disord DOI: 10.1002/eat.23303 sha: doc_id: 309769 cord_uid: phi3re5g The COVID‐19 pandemic has impacted research around the globe and required shuttering of research programs and the implementation of procedural adjustments to ensure safety. That COVID-19 disrupted eating disorders research is, of course, not an unexpected finding; however, the extent of studies that needed to be halted is noteworthy.
    keywords: concern; covid-19; disorders; eating; positions; research; respondents; stress; survey
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        item: #4376 of 7819
          id: cord-309799-fhkbcp7z
      author: Hwang, Yerin
       title: Diabetes and COVID-19: IDF perspective in the Western Pacific Region
        date: 2020-06-25
       words: 2781
      flesch: 40
     summary: These include seven versions of the diagnosis and treatment protocol, three editions of the protocol for severe and critical cases, two editions of the manual for mild case management, two editions of convalescent plasma therapy treatment protocol, and one rehabilitation treatment program for patients discharged from hospitals 7 . 3) Japan -Since early April 2020 with the sharp increase in the number of COVID-19 cases, the health care systems in Japan has barely evaded collapse by ramping up the number of hospital beds dedicated to those with the disease (more than 12,000 beds nationwide) as well as by reallocating medical resources. However, by March 21 st 2020, when COVID-19 positive cases in Australia exceeded 1,000 with 7 deaths, Australia was clearly on the exponential part of the curve 6 .
    keywords: cases; covid-19; diabetes; hospitals; national; pandemic; patients; treatment
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        item: #4377 of 7819
          id: cord-309809-zvh2k97q
      author: Knepple Carney, Amy
       title: Age Moderates Perceived COVID-19 Disruption on Well-being
        date: 2020-08-18
       words: 3251
      flesch: 50
     summary: Older adults showed the highest levels of resilience following the September 11(th) (9/11) terrorist attacks, but during the severe acute respiratory syndrome (SARS) outbreak there were no age-related differences in well-being. Findings are consistent with the strength and vulnerability integration (SAVI) model, wherein older adults try to maintain positive emotional well-being; with middle-aged and older adults in the current study having experienced less negative impact on well-being.
    keywords: adults; age; covid-19; disruption; stress
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        item: #4378 of 7819
          id: cord-309823-fwa6mpb9
      author: Stergachis, Andy
       title: Preparing pharmacy for the surge of patients with COVID-19: Lessons from China
        date: 2020-04-10
       words: 962
      flesch: 38
     summary: As one of the first descriptions of pharmacy services provided during the COVID-19 pandemic, Hua et al 6 are to be commended for their efforts and for sharing their experiences. Vaccine Pharmacy administration and pharmaceutical care practice in module hospital under COVID-19 epidemic Providing pharmacy services during the coronavirus pandemic The Chinese Pharmaceutical Association.
    keywords: care; covid-19; patients; pharmacy
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        item: #4379 of 7819
          id: cord-309826-xutv2x8p
      author: Baud, Grégory
       title: Chirurgie endocrinienne au cours et au décours de l’épidémie de COVID-19: Recommandations de l’AFCE
        date: 2020-04-30
       words: 2240
      flesch: 37
     summary: En l'absence de signe d'agressivité locorégionale, le délai de la prise en charge chirurgicale d'un carcinome différencié dépendra Bien que le pronostic des carcinomes médullaires de la thyroïde (CMT) soit légèrement moins favorable que celui des cancers de souche folliculaire (14), cela ne modifie pas les recommandations ci-dessus en terme de délai de prise en charge.
    keywords: des; les; épidémique; être
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        item: #4380 of 7819
          id: cord-309829-3dlfcy31
      author: Parupudi, Tejasvi
       title: Evidence-based point-of-care technology development during the COVID-19 pandemic
        date: 2020-11-09
       words: 4776
      flesch: 40
     summary: Diagnostic tests are actively useful and improve patient outcomes only when they are used in the right settings. [8] described emerging diagnostic platforms, developmental phases of diagnostic tests and the role of smartphone capabilities such as connectivity, databasing and onboard hardware in formulating evidencebased disease response for policy makers and healthcare systems worldwide.
    keywords: blood; care; cov-2; covid-19; detection; disease; patient; point; sars; testing; tests; use
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        item: #4381 of 7819
          id: cord-309830-3iztragp
      author: Zhang, Yang
       title: Commentary: Challenges to thoracic surgeons in the global coronavirus pandemic
        date: 2020-04-10
       words: 624
      flesch: 51
     summary: It is important to avoid unnecessary surgeries and to be alert to the risk of COVID-19 infection following thoracic surgeries. It is important to avoid unnecessary surgeries and to be alert to the risk of COVID-19 infection following thoracic surgeries.
    keywords: surgeries; thoracic
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        item: #4382 of 7819
          id: cord-309864-yzb3si3w
      author: Smeda, Marta
       title: Endothelial barrier integrity in COVID-19-dependent hyperinflammation: does the protective facet of platelet function matter?
        date: 2020-08-01
       words: 1587
      flesch: 13
     summary: key: cord-309864-yzb3si3w authors: Smeda, Marta; Chlopicki, Stefan title: Endothelial barrier integrity in COVID-19-dependent hyperinflammation: does the protective facet of platelet function matter? date: 2020-08-01 journal: Cardiovasc Res DOI: 10.1093/cvr/cvaa190 sha: doc_id: 309864 cord_uid: yzb3si3w nan The characteristic feature of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (COVID-19 disease) is that its course is asymptomatic or mild in the majority of cases, while increasing age and/or underlying cardiovascular diseases predispose for a severalfold increased case fatality rate. The mechanisms of plateletdependent maintenance of endothelial barrier integrity also seem to be critical in the context of viral infections as their impairment results in bleeding and vascular damage.
    keywords: barrier; covid-19; mechanisms; platelet
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        item: #4383 of 7819
          id: cord-309886-j63cpzj2
      author: Pacha, Omar
       title: COVID-19: a case for inhibiting IL-17?
        date: 2020-05-01
       words: 1574
      flesch: 32
     summary: The shift to pro-inflammatory cytokine production in the lungs is pathologically characterized by diffuse alveolar damage with numerous neutrophils and protein rich oedema in the alveolar space. Immunomodulation is not a novel idea as a means to improve outcomes of COVID-19 ARDS.
    keywords: ards; covid-19; il-17; patients
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        item: #4384 of 7819
          id: cord-309930-zlzuoeh2
      author: Zhou, Zhiming
       title: Coronavirus disease 2019: initial chest CT findings
        date: 2020-03-24
       words: 4239
      flesch: 45
     summary: The Chongqing Three Gorges Central Hospital, located in the northeast of Chongqing and connected to Hubei Province, is one of the designated hospitals for the centralized treatment of pneumonia patients infected by the SARS-CoV-2 and has received a large number of COVID-19 patients. Finally, 62 confirmed COVID-19 patients (34 men, 28 women; age range 20-91 years old) who had not received antiviral treatment were retrospectively reviewed.
    keywords: chest; coronavirus; covid-19; disease; group; patients; sars; stage
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        item: #4385 of 7819
          id: cord-309931-cpzp33b3
      author: Zawawi, Ayat
       title: The impact of COVID-19 pandemic on malaria elimination
        date: 2020-10-20
       words: 4189
      flesch: 44
     summary: The overuse of CQ in India might lead to a shortage of CQ and thus might increase the number of morbidity and mortality due to malaria infection during COVID-19 crisis. Severe malaria infection is usually associated with multi-organ failure in adults and respiratory distress in children, presenting what is commonly seen in COVID-19 infected patients [41] .
    keywords: africa; control; coronavirus; countries; covid-19; health; infection; malaria; sars; world
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        item: #4386 of 7819
          id: cord-309946-1j8ewpcf
      author: Jorge-Pérez, Pablo
       title: Recomendaciones en reanimación cardiopulmonar en pacientes con COVID-19
        date: 2020-05-04
       words: 1813
      flesch: 36
     summary: En este contexto el reconocimiento precoz es vital, y tras ello se debe priorizar la desfibrilación a las compresiones y el control de la vía aérea 10 . En el caso de la RCP es importante destacar que las 2 premisas fundamentales deben ser la protección del equipo humano y reanimar primando
    keywords: con; covid-19; del; las; los; pandemia; por; que; rcp; resuscitation; una
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        item: #4387 of 7819
          id: cord-309950-nutxlvmm
      author: Vieira, André
       title: Rapid Estimation of Excess Mortality during the COVID-19 Pandemic in Portugal -Beyond Reported Deaths
        date: 2020-09-17
       words: 2736
      flesch: 53
     summary: London: Escola Nacional de Saúde Pública Short-term forecasts of COVID-19 deaths in multiple countries. Forty-nine percent of excess deaths were caused by COVID-19 and another 51% were attributed to other natural causes.
    keywords: covid-19; deaths; excess; march; mortality; years
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        item: #4388 of 7819
          id: cord-309970-jkmjiika
      author: Liu, Qin
       title: From SARS to COVID-19: What lessons have we learned?
        date: 2020-08-21
       words: 3427
      flesch: 47
     summary: Notice on the issuance of COVID-19 protocol (trial seventh edition) 2019-nCoV transmission through the ocular surface must not be ignored The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Covert coronavirus infections could be seeding new outbreaks Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship Clinical manifestations, laboratory findings, and treatment outcomes of SARS patients Severe acute respiratory syndrome (SARS): imaging findings during the acute and recovery phases of disease Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study A major outbreak of severe acute respiratory syndrome in Hong Kong SARS-CoV-2 Infection in Children Pathological findings of COVID-19 associated with acute respiratory distress syndrome Thoughts on the etiology and pathogenesis of COVID-19 in Traditional Chinese medicine Symptom-based stratification of autoimmune diseases Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2) SARS patients mainly present with fever and chills, accompanied by systemic and respiratory symptoms including mild fever and muscle pain.
    keywords: cases; china; coronavirus; cov-2; covid-19; disease; epidemic; patients; sars
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        item: #4389 of 7819
          id: cord-309981-4p3ybrn1
      author: Dai, Ling-Ling
       title: Anxiety and depressive symptoms among COVID-19 patients in Jianghan Fangcang Shelter Hospital in Wuhan, China
        date: 2020-08-28
       words: 3561
      flesch: 39
     summary: Among them, 57 (18.6%) experienced anxiety symptoms, and 41 (13.4%) experienced depressive symptoms. Based on covariates with P < 0.10 as screening covariates, having a family member who has been confirmed with COVID-19, number of current physical symptoms, symptoms change after hospitalization, and poor sleep quality were the related factors of anxiety symptoms, and gender, education level, smoking history, drinking history, having a family member who has been confirmed COVID-19, number of current physical symptoms, symptoms change after hospitalization, and poor sleep quality were the related factors of depressive symptoms (see Table 1 ).
    keywords: anxiety; covid-19; fangcang; patients; quality; shelter; sleep; symptoms
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        item: #4390 of 7819
          id: cord-309983-lpawbk7s
      author: Rousan, Liqa A.
       title: Chest x-ray findings and temporal lung changes in patients with COVID-19 pneumonia
        date: 2020-09-15
       words: 4095
      flesch: 57
     summary: Patients’ demographics, clinical characteristics, and chest x-ray findings were reported. Information on chest x-ray findings in patients with COVID-19 pneumonia is still limited in the literature and the majority of the reports described the lung changes on chest CT scan.
    keywords: chest; covid-19; findings; patients; ray; rays
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        item: #4391 of 7819
          id: cord-309986-p7pqla6l
      author: Harkin, Timothy J
       title: Delayed diagnosis of COVID-19 in a 34-year-old man with atypical presentation
        date: 2020-05-18
       words: 2116
      flesch: 45
     summary: On hospital day 9, bronchoscopy was done with appropriate personal and environmental protection precautions for COVID-19, including intubation. Alternatively, a different infection might have caused the early sepsis presentation, with clinical improvement up to day 4 related to appropriate treatment with antibiotics, after which COVID-19 manifested on day 5, causing clinical worsening.
    keywords: bal; cov-2; covid-19; day; patient; sars
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        item: #4392 of 7819
          id: cord-309987-vvt1x151
      author: Camacho-Rivera, Marlene
       title: Associations Between Chronic Health Conditions and COVID-19 Preventive Behaviors Among a Nationally Representative Sample of U.S. Adults: An Analysis of the COVID Impact Survey
        date: 2020-08-05
       words: 3795
      flesch: 37
     summary: We used multivariable logistic regression models to model associations between COVID-19 preventive behaviors across demographic and health characteristics. Conclusion: This study provides U.S. national prevalence estimates and differences in adherence to COVID-19 preventive behaviors among those with and without the presence of underlying chronic health conditions.
    keywords: adults; conditions; covid-19; disease; health; prevalence
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        item: #4393 of 7819
          id: cord-310026-j418v75n
      author: Miller, Jemima H.
       title: Impact of coronavirus disease 2019 (COVID-19) pandemic isolation measures on the rate of non–COVID-19 infections in hematology patients
        date: 2020-10-20
       words: 1178
      flesch: 44
     summary: The incidence of respiratory virus infection was lower in 2020 with 29 of 143 (20.27%) positive tests in 2019 compared to 29 of 266 (10.90%) in 2020 (P = .01). 4,5 Therefore, increased awareness and utilization of infection control measures is vital for reducing rates of infection.
    keywords: covid-19; infection; patients; pcr
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        item: #4394 of 7819
          id: cord-310027-846vp7ii
      author: Ma, Lin-Lu
       title: Coronavirus Disease 2019 Related Clinical Studies: A Cross-Sectional Analysis
        date: 2020-09-02
       words: 4252
      flesch: 43
     summary: We did an electronic search of COVID-19 related clinical studies registered between December 1, 2019 and February 21, 2020 (updated to May 28, 2020) from the ClinicalTrials.gov, and collected registration information, study details, recruitment status, characteristics of the subjects, and relevant information about the trial implementation process. Registration of COVID-19 related clinical studies is ongoing.
    keywords: coronavirus; covid-19; patients; registration; studies; study; treatment; trials
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        item: #4395 of 7819
          id: cord-310042-9z8rkzq8
      author: Aysha, Al‐Ani
       title: Practical management of inflammatory bowel disease patients during the COVID‐19 pandemic: expert commentary from the Gastroenterological Society of Australia Inflammatory Bowel Disease faculty
        date: 2020-07-12
       words: 3473
      flesch: 37
     summary: A significant proportion of IBD patients are treated with long-term immunomodulator/immunosuppressive therapy which potentially places them at increased risk of infections and associated complications. Despite concerns regarding immunosuppression and consequent predisposition to infection, there is no evidence to suggest increased infection rates of COVID-19 in IBD patients to date.
    keywords: cov-2; covid-19; disease; ibd; infection; patients; risk; sars; symptoms
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        item: #4396 of 7819
          id: cord-310060-ymoxt1zq
      author: Liu, Fengjun
       title: CT quantification of pneumonia lesions in early days predicts progression to severe illness in a cohort of COVID-19 patients
        date: 2020-04-27
       words: 4045
      flesch: 45
     summary: On day 4, all three CT features were significantly higher in severe patients than in non-severe patients (all P<0.001). In one epidemical report of COVID-19 by China Center for Disease Control (CDC), among 44,672 confirmed cases, severe patients accounted for 13.8%, and critically ill patients accounted for 4.7%
    keywords: covid-19; day; dimer; features; illness; nlr; patients; study
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        item: #4397 of 7819
          id: cord-310073-ncj500af
      author: Falkingham, J.
       title: Sleepless in Lockdown: unpacking differences in sleep loss during the coronavirus pandemicin the UK
        date: 2020-07-21
       words: 3602
      flesch: 41
     summary: For the purposes of the main analysis we group the first two options as indicating no problem of increased sleep loss due to worry and the latter two options as indicating a problem of sleep loss. Among women, being a key worker was a risk factor and being a BAME was a protective factor for increased sleep loss whilst both these factors were not associated with sleep loss for men.
    keywords: coronavirus; covid-19; health; loss; pandemic; sleep; women
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        item: #4398 of 7819
          id: cord-310084-taaz6mhs
      author: Fatehi, Poya
       title: Acute Ischemic and Hemorrhagic Stroke and COVID-19: Case Series
        date: 2020-10-01
       words: 3012
      flesch: 49
     summary: Evidence from previous studies have indicated that patients with severe coronavirus disease might experience respiratory failure with an urgent need for artificial respiration, and other organ dysfunction [7] . His first symptoms were cough and shortness of breath 1 week before hospitalization when he was referred to an allergy specialist and was diagnosed with coronavirus disease after testing for RT-PCR and a confirmative CT scan of the chest.
    keywords: blood; brain; coronavirus; covid-19; patient; scan
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        item: #4399 of 7819
          id: cord-310104-1c7q9m06
      author: Sasangohar, Farzan
       title: Provider Burnout and Fatigue During the COVID-19 Pandemic: Lessons Learned From a High-Volume Intensive Care Unit
        date: 2020-04-20
       words: 3254
      flesch: 38
     summary: While business is booming in health care, all indicators point to a likely sustained overall economic downturn. • The national and regional disaster mitigation plans for future epidemics have to incorporate mechanisms to allow rapid and agile transformation of relevant industry to support massively increased demand for disinfectants, cleaning supplies, PPE, and other medical equipment for health care and community use.
    keywords: care; covid-19; fatigue; health; hmh; icu; pandemic; ppe; stress; system; workers
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        item: #4400 of 7819
          id: cord-310105-a4fzp6bn
      author: Kamdar, Hera A.
       title: Clinician's Perception of Practice Changes for Stroke During the COVID-19 Pandemic: Perception of Practice Changes for Stroke During COVID-19
        date: 2020-07-22
       words: 2120
      flesch: 40
     summary: Our study demonstrated the rapidly changing environment surrounding stroke patients in the era of COVID-19. Many respondents also felt that the outcome or care of stroke patients at his or her institution had been impacted by the COVID-19 pandemic.
    keywords: acute; care; covid-19; pandemic; patients; stroke
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        item: #4401 of 7819
          id: cord-310108-glikeowu
      author: Ghosh, Amerta
       title: COVID19 induced acute pancreatitis and pancreatic necrosis in a patient with type 2 diabetes
        date: 2020-10-10
       words: 973
      flesch: 44
     summary: In absence of any known etiology of pancreatitis, radiological findings of necrosis of pancreatic body and tail (Fig.1) , increased lipase along with COVID-19 infection confirms the relationship between acute pancreatitis and COVID-19 in our case. In any case of pancreatitis, common causes of acute pancreatitis must be ruled out before diagnosis of COVID19 induced pancreatitis.
    keywords: acute; case; covid-19; pancreatitis
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        item: #4402 of 7819
          id: cord-310115-uooszsta
      author: White, Ross G.
       title: Impact of the COVID-19 pandemic and initial period of lockdown on the mental health and well-being of adults in the UK
        date: 2020-08-17
       words: 1876
      flesch: 42
     summary: Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019 COVID19 pandemic and lockdown measures impact on mental health among the general population in Italy. medRxiv Creating Capabilities: The Human Development Approach How groups affect our health and well-being: the path from theory to policy The Hospital Anxiety and Depression Scale Well-Being Measures in Primary Health Care: The DepCare Project Operationalising the capability approach for outcome measurement in mental health research The Multidimensional Scale of Perceived Social Support Normative data for the Hospital Anxiety and Depression Scale Social connectedness improves public mental health: investigating bidirectional relationships in the New Zealand attitudes and values survey The use of Facebook in recruiting participants for health research purposes: a systematic review R.G.W. formulated the research questions, designed the study, conducted the study, analysed the data and wrote the article.
    keywords: covid-19; health
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        item: #4403 of 7819
          id: cord-310117-19qsszns
      author: Huang, Yao
       title: Clinical characteristics of 17 patients with COVID-19 and systemic autoimmune diseases: a retrospective study
        date: 2020-06-16
       words: 3706
      flesch: 47
     summary: Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting or dissemination plans of this research. This proportion was significantly higher than the study reported on 1099 patients, 7 presumably because more patients with severe COVID-19 were admitted to Tongji Hospital.
    keywords: aids; clinical; covid-19; disease; hospital; patients; study; tongji; wuhan
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        item: #4404 of 7819
          id: cord-310123-h7i49pdb
      author: De Smet, Robert
       title: Frailty and mortality in hospitalized older adults with COVID-19: retrospective observational study
        date: 2020-06-09
       words: 3322
      flesch: 48
     summary: 44 A retrospective, single-center observational study was performed among COVID-19 patients at the 47 Geriatrics Department of our General Hospital in Belgium, admitted between March 12 th and April 48 30 th , 2020. Further 164 work is needed to establish optimal clinical, viral and host immune system characteristics to predict 165 mortality among COVID-19 patients.
    keywords: age; care; cfs; covid-19; frailty; mortality; patients
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        item: #4405 of 7819
          id: cord-310144-s25do8cb
      author: Lara-Reyna, Jacques
       title: “Staying Home” - Early Changes in Patterns of Neurotrauma in New York City during the COVID-19 Pandemic
        date: 2020-07-27
       words: 3839
      flesch: 48
     summary: Healthcare institutions in NYC witnessed an exponential growth of COVID-19 cases since March 3, with the highest peak of 6,368 diagnoses on April 6th, and a peak of 590 deaths on April 7th. The weekly maximum peak of COVID-19 cases was observed between March 22th and March 31st, three weeks after the first case was reported in NYC, and one week after the Executive Order started.
    keywords: cases; covid-19; frequency; injury; pandemic; patients; period; pre; trauma
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        item: #4406 of 7819
          id: cord-310149-8idvf79g
      author: Antinori, Spinello
       title: SARS-COV-2 infection: Across the border into the family
        date: 2020-06-09
       words: 927
      flesch: 32
     summary: Serological testing of the five family members involved in a probable COVID-19 cluster Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lumbardy Region Characteristics of COVID-19 infection in Beijng Suppression of COVID-19 outbreak in the municipalità of Vò Covid-19 in Italy: lesson from the Veneto Region Drawing on Israel's experience organizing volunteers to operationalize drive-through Coronavirus testing centers Self-reported olfactory and taste disorders in SARS-CoV-2 patients: a cross-sectional study Dr Carlo Parravicini for assistance in figure production Written informed consent was obtained from all of the subjects, including the parents of the children None The decision not to search for SARS-COV-2 in people with mild symptoms and not to include them in surveillance programmes is at least questionable, particularly because the future relaxation of containment measures will require even more active surveillance in order to ensure the early detection of new cases or clusters.
    keywords: antinori; covid-19; family
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        item: #4407 of 7819
          id: cord-310150-j1mvr9r9
      author: Wei, Wei
       title: Identification of common and severe COVID-19: the value of CT texture analysis and correlation with clinical characteristics
        date: 2020-07-01
       words: 3113
      flesch: 50
     summary: This retrospective study was performed to analyze the correlations among CT texture features, clinical features, and clinical subtypes of COVID-19 and to explore the value of CT texture analysis in determining the severity of COVID-19. The prediction model based on CT text features achieved a sensitivity of 0.80 and a specificity of 0.95, which means that CT texture analysis can early accurately assess disease severity.
    keywords: analysis; covid-19; features; patients; radiomics; texture
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        item: #4408 of 7819
          id: cord-310157-gzysuusk
      author: Piapan, Linda
       title: COVID-19 outbreak in healthcare workers in Trieste hospitals (North-Eastern Italy)
        date: 2020-08-14
       words: 733
      flesch: 51
     summary: The vast majority of COVID-19 HCWs were employed in medical wards, with a significantly increased prevalence in Geriatric and Infectious Diseases (42.6%) (OR 67.9; CI 34.7-133) and Internal Medicine I and II (29.6%) (OR 9.6; CI 5.6-16.5). key: cord-310157-gzysuusk authors: Piapan, Linda; De Michieli, Paola; Ronchese, Federico; Rui, Francesca; Mauro, Marcella; Peresson, Maria; Segat, Ludovica; D’Agaro, Pierlanfranco; Negro, Corrado; Bovenzi, Massimo; Filon, Francesca Larese title: COVID-19 outbreak in healthcare workers in Trieste hospitals (North-Eastern Italy) date: 2020-08-14 journal: Journal of Hospital Infection DOI: 10.1016/j.jhin.2020.08.012 sha: doc_id: 310157 cord_uid: gzysuusk nan The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first reported in Wuhan, China, on December 2019 has rapidly become an increasing health concern worldwide [1].
    keywords: cases; covid-19; hcws
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        item: #4409 of 7819
          id: cord-310159-l9hfmmbc
      author: Chowdhury, Subhankar
       title: COVID-19 and type 1 diabetes: dealing with the difficult duo
        date: 2020-07-14
       words: 3572
      flesch: 41
     summary: Possible explanations for the same include a younger age of T1D patients, lower prevalence of T1D, and overexpression of CD8+ T lymphocytes in T1D which might play a protective role (CD8+ T lymphocytes show an increased apoptosis leading to lymphocytopenia in SARS-COV2 infection) However, population cohort studies covering all individuals registered with a general practice in England show that T1D patients do contract COVID-19 infection requiring hospitalisation in some [14, 15] .
    keywords: covid-19; diabetes; disease; dka; insulin; patients; risk; t1d; type
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        item: #4410 of 7819
          id: cord-310165-xj025ruz
      author: Jones, Rodney P
       title: Would the United States Have Had Too Few Beds for Universal Emergency Care in the Event of a More Widespread Covid-19 Epidemic?
        date: 2020-07-19
       words: 6734
      flesch: 56
     summary: key: cord-310165-xj025ruz authors: Jones, Rodney P title: Would the United States Have Had Too Few Beds for Universal Emergency Care in the Event of a More Widespread Covid-19 Epidemic? date: 2020-07-19 journal: Int J Environ Res Public Health DOI: 10.3390/ijerph17145210 sha: doc_id: 310165 cord_uid: xj025ruz (1) Background: To evaluate the level of hospital bed numbers in U.S. states relative to other countries using a new method for evaluating bed numbers, and to determine if this is sufficient for universal health care during a major Covid-19 epidemic in all states (2) Methods: Hospital bed numbers in each state were compared using a new international comparison methodology. (3) Results: Hospital bed numbers show large variation between U.S. states and half of the states have equivalent beds to those in developing countries.
    keywords: beds; care; countries; covid-19; deaths; hospital; new; population; states; u.s
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        item: #4411 of 7819
          id: cord-310166-gt6icwul
      author: Yang, Xiang-Hong
       title: Expert recommendations on blood purification treatment protocol for patients with severe COVID-19(): Recommendation and consensus
        date: 2020-04-28
       words: 3131
      flesch: 41
     summary: The specific contents include the choice of mode of blood purification treatment, establishment of vascular access, choice of blood purification filter, anticoagulation scheme, treatment dose, and initial parameter settings. Based on the experiences of performing blood purification for patients with severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome combined with the first-line clinical practice of blood purification in the treatment of patients with severe COVID-19, we formulated a process of blood purification treatment for patients with severe COVID-19.
    keywords: aki; blood; coronavirus; covid-19; patients; purification; step; treatment
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        item: #4412 of 7819
          id: cord-310184-qth1y88o
      author: Alunno, Alessia
       title: Storm, typhoon, cyclone or hurricane in patients with COVID-19? Beware of the same storm that has a different origin
        date: 2020-05-18
       words: 2987
      flesch: 29
     summary: Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Role of immunosuppressive therapy in rheumatic diseases concurrent with COVID-19 Aberrant pathogenic GM-CSF+ T cells and inflammatory CD14+CD16+ monocytes in severe pulmonary syndrome patients of a new coronavirus On the alert for cytokine storm: immunopathology in COVID-19 COVID-19: consider cytokine storm syndromes and immunosuppression The role of cytokines including interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease Cytokine release syndrome: current perspectives Adult haemophagocytic syndrome Recommendations for the management of hemophagocytic lymphohistiocytosis in adults Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by COVID-19: anti-inflammatory strategies Lung pathology of fatal severe acute respiratory syndrome HLH-2004:diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis Development and validation of the HScore, a score for the diagnosis of reactive hemophagocytic syndrome Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China The hyperferritinemic syndrome: macrophage activation syndrome, Still's disease, septic shock and catastrophic antiphospholipid syndrome Emergent high fatality lung disease in systemic juvenile arthritis New functions for an iron storage protein: the role of ferritin in immunity and autoimmunity Ferritin to erythrocyte sedimentation rate ratio: simple measure to identify macrophage activation syndrome in systemic juvenile idiopathic arthritis COVID-19 infection in children Kawasaki disease: the role of immune complexes revisited Macrophage activation syndrome in Kawasaki disease: more common than we thought? Classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative The different clinical characteristics of corona virus disease cases between children and their families in China -the character of children with COVID-19 COVID-19 in children and altered inflammatory responses Epidemiology and clinical features of coronavirus disease 2019 in children COVID-19 illness in native and immunosuppressed states: a clinical-therapeutic staging proposal Cytokines in sepsis: potent immunoregulators and potential therapeutic targets: an updated view Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury Contributors AA, FC and JRC drafted, read and approved the final manuscript. 6 7 However, to guide therapeutic decisions, the heterogeneity under the umbrella of cytokine storm syndromes must be appraised.
    keywords: covid-19; cytokine; disease; ferritin; lung; patients; storm; syndrome
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        item: #4413 of 7819
          id: cord-310190-405m9bco
      author: Kim, Tark
       title: Strategical Preparedness and Response Actions in the Healthcare System Against Coronavirus Disease 2019 according to Transmission Scenario in Korea
        date: 2020-07-22
       words: 1732
      flesch: 37
     summary: The national influenza surveillance system of Korea FAQs on public health preparedness clinic (PHPC) scheme Hanm city respiratory infection clinic responsible for safe healthcare service Drive-through screening center for COVID-19: a safe and efficient screening system against massive community outbreak Korean Center for Disease Control and prevention (KCDC). Above all, public hospitals should be dedicated to treating COVID-19 patients with asymptomatic infection or mild illness.
    keywords: covid-19; health; healthcare; patients; system
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        item: #4414 of 7819
          id: cord-310207-lfub6y5m
      author: Nanda, Satyan
       title: Covid-19 associated Guillain-Barre Syndrome: Contrasting tale of four patients from a tertiary care centre in India
        date: 2020-09-16
       words: 1318
      flesch: 46
     summary: Less frequent involvement of cranial nerves in GBS secondary to Covid-19 is also in contrast to Zika virus associated GBS, where facial and third nerve involvement was quite common [7] . All our patients developed features of GBS, 5-10 days after the onset of Covid-19 symptoms, which is similar to the interval seen with Guillain-Barré syndrome that occurs secondary to other infections [9] .
    keywords: covid-19; days; gbs; syndrome
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        item: #4415 of 7819
          id: cord-310228-bqpvykce
      author: Borkowski, A. A.
       title: Using Artificial Intelligence for COVID-19 Chest X-ray Diagnosis
        date: 2020-05-26
       words: 3194
      flesch: 44
     summary: In addition, we describe the creation of a publicly available website that could augment COVID-19 pneumonia CXR diagnosis. 24 Most of the literature evaluating radiographs of COVID-19 patients .
    keywords: chest; covid-19; cxr; images; patients; pneumonia
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        item: #4416 of 7819
          id: cord-310245-r1fd2kqh
      author: Lin, Chung-Ying
       title: Investigating mediated effects of fear of COVID-19 and COVID-19 misunderstanding in the association between problematic social media use, psychological distress, and insomnia
        date: 2020-08-27
       words: 2884
      flesch: 37
     summary: The FCV-19S item scores were summed, with a higher score indicating a greater level of COVID-19 fear. The same study also found that more than 90% of the participants obtained COVID-19 information from internet and they were keen to know more about COVID-19, including the COVID-19 transmission route, the medication and vaccine availability and effectiveness, travel advice, overseas COVID-19 control experiences, the number of confirmed cases with locations, COVID-19 prevention advice, tailored-made information for different populations (e.g., children and individuals with chronic illnesses), and detailed information on COVID-19 infection symptoms .
    keywords: covid-19; distress; fear; insomnia; media; misunderstanding; use
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        item: #4417 of 7819
          id: cord-310254-ko1sptzm
      author: Attri, Bhawna
       title: Basal-Bolus Insulin Regimen for Hospitalised Patients with COVID-19 and Diabetes Mellitus: A Practical Approach
        date: 2020-07-18
       words: 6399
      flesch: 44
     summary: The basal insulin regulates the rise in blood glucose due to endogenous glucose production through the processes of glycogenolysis and gluconeogenesis, and the bolus insulin prevents the meal-related rise in blood glucose levels. This gap ensures that the release of prandial insulin is appropriate to match the post-meal rise in blood glucose and that there is no second unregulated wave of glucose release during this period.
    keywords: blood; blood glucose; covid-19; diabetes; glucose; insulin; mmol; patients
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        item: #4418 of 7819
          id: cord-310288-onr700ue
      author: Sciubba, Daniel M.
       title: Scoring system to triage patients for spine surgery in the setting of limited resources: Application to the COVID-19 pandemic and beyond
        date: 2020-05-29
       words: 3595
      flesch: 37
     summary: key: cord-310288-onr700ue authors: Sciubba, Daniel M.; Ehresman, Jeff; Pennington, Zach; Lubelski, Daniel; Feghali, James; Bydon, Ali; Chou, Dean; Elder, Benjamin D.; Elsamadicy, Aladine A.; Goodwin, C. Rory; Goodwin, Matthew L.; Harrop, James; Klineberg, Eric O.; Laufer, Ilya; Lo, Sheng-Fu L.; Neuman, Brian J.; Passias, Peter G.; Protopsaltis, Themistocles; Shin, John H.; Theodore, Nicholas; Witham, Timothy F.; Benzel, Edward C. title: Scoring system to triage patients for spine surgery in the setting of limited resources: Application to the COVID-19 pandemic and beyond date: 2020-05-29 journal: World Neurosurg DOI: 10.1016/j.wneu.2020.05.233 sha: doc_id: 310288 cord_uid: onr700ue Abstract Background As of May 04, 2020, the COVID-19 pandemic has affected over 3.5 million people and touched every inhabited continent. 202 203 204 Limitations 205 As with scoring systems published in other domains of neurosurgery, the present scoring system 206 is not intended to be prescriptive in its guidance.
    keywords: cases; covid-19; elective; emergent; pandemic; scoring; spine; system
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        item: #4419 of 7819
          id: cord-310293-0s7l0l4k
      author: Salman, Saima
       title: Inter-hospital communication and transfer practices during COVID-19 Pandemic in Karachi, Pakistan. A brief overview
        date: 2020-05-17
       words: 1482
      flesch: 45
     summary: In addition to the extensive planning required to cater to patients with COVID 19 in hospitals as well as instructions for home quarantine in stable patients, the undertaking also involves establishment of state run quarantine facilities, establishment of protocols for surge capacity and liaison between healthcare facilities and government for proper patient management. The need for expeditious transfer of patients among various hospitals has always been voiced at various forums but no measures have been taken so far in the form of well-defined pathways and SOPs, neither between hospitals nor at the level of policy makers.
    keywords: covid; facilities; hospital; pakistan; patients
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        item: #4420 of 7819
          id: cord-310304-f28tjmi8
      author: Alcendor, Donald J.
       title: Racial Disparities-Associated COVID-19 Mortality among Minority Populations in the US
        date: 2020-07-30
       words: 7730
      flesch: 35
     summary: Aggressive strategies to help minority patients at higher risk understand the seriousness of COVID-19 disease could include direct mailings, providing patients with samples of masks and sanitizers, COVID-19 office placards, COVID-19 infomercials in waiting areas, wellness checks, and COVID-19 information for family members and caretakers. COVID-19 patients with diabetes are at increased risk of having adverse clinical complications, including death [37, 38] .
    keywords: ace2; angiotensin; coronavirus; cov-2; covid-19; diabetes; disease; health; infection; minority; patients; respiratory; risk; sars
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        item: #4421 of 7819
          id: cord-310315-w4rgjsbl
      author: Belhadi, Amine
       title: Infectious Waste Management Strategy during COVID-19 Pandemic in Africa: an Integrated Decision-Making Framework for Selecting Sustainable Technologies
        date: 2020-10-23
       words: 8484
      flesch: 38
     summary: As for infectious WW treatment alternatives, UF (WW4) is economically the best alternative, although the low job creation due to the simplicity of processes compared to the other methods. Regarding infectious SW treatment alternatives, acceptable advantage, the cond.1 in Step 5 is satisfied among line SW3 (Q 3 = 0.102) and SW1 (Q 1 = 0.498).
    keywords: alternatives; countries; covid-19; criteria; decision; disinfection; et al; evaluation; infectious; ivf; management; pandemic; study; treatment; waste; ww treatment
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        item: #4422 of 7819
          id: cord-310339-1e16yncy
      author: Maxam, Meshell
       title: Development and Implementation of a COVID-19 Disease Response Protocol at a Large Academic Medical Center
        date: 2020-05-22
       words: 2200
      flesch: 34
     summary: The document contains best practices and guidance for diagnosis, isolation, appropriate personal protective equipment for the care of COVID-19 patients, guidelines for transportation, diagnostic tests, investigational COVID-19 treatment options, a summary of ongoing clinical trials at our facilities, how to mitigate additional transmissions, and education for patients and families. As new data became available, including the National Institutes of Health updated recommendations for the management of COVID-19 patients on April 21, 2020, the aforementioned stakeholders were involved in determining which investigational treatment options and clinical trials were available for the health system's patient population.
    keywords: care; clinical; covid-19; health; infection; protocol; treatment
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        item: #4423 of 7819
          id: cord-310348-8iix257c
      author: Han, Jason J.
       title: Ethical Guidelines and Moral Distress During the COVID-19 Pandemic: The Trainees’ Perspective
        date: 2020-06-05
       words: 486
      flesch: 40
     summary: We applaud cardiothoracic surgery leadership for their development of resource utilization predictions tools based on data from the Society of Thoracic Surgeons Database to assist healthcare providers in making informed resource allocation 2 decisions and triaging cardiothoracic surgical cases. COVID-19 Guidance for Triage of Operations for Thoracic Malignancies: A Consensus Statement from Thoracic Surgery Outcomes Research Network
    keywords: cardiothoracic; surgery
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        item: #4424 of 7819
          id: cord-310390-7pkbd3kg
      author: Han, Xiaoyu
       title: Novel Coronavirus Pneumonia (COVID-19) Progression Course in 17 Discharged Patients: Comparison of Clinical and Thin-Section CT Features During Recovery
        date: 2020-03-30
       words: 3178
      flesch: 53
     summary: When analyzing the evolution of CT findings, the present study had identified three patterns of radiographic progression ( Figure 3 ). When analyzing the evolution of CT finding of all patients by time, the 12 present study found that most patients recovering from COVID-19 showed an initial radiographic deterioration to a peak (mean time, 2 nd week) followed by radiographic improvement in the 3 rd and 4 th week.
    keywords: clinical; coronavirus; covid-19; improvement; novel; patients; week
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        item: #4425 of 7819
          id: cord-310401-39jjedq0
      author: Antwi-Amoabeng, D.
       title: Sociodemographic predictors of outcomes in COVID-19: examining the impact of ethnic disparities in Northern Nevada
        date: 2020-05-25
       words: 2719
      flesch: 40
     summary: For instance, in New York City, the crude death rate for Hispanics is 21.3 per 100,000 as compared to 15.7 per 100,000 in non-Hispanic whites and 9.1 per 100,000 in non-Hispanic Asians [14] . Demographic and clinical characteristics were compared by ethnic group (Hispanic versus non-Hispanic).
    keywords: covid-19; hispanic; license; medrxiv; non; preprint
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        item: #4426 of 7819
          id: cord-310405-7fah22nu
      author: Mathur, Sachin
       title: Development of an enhanced Acute Care Surgery service in response to the COVID-19 global pandemic: Assessment of clinical patient outcomes and staff psychological well-being
        date: 2020-06-25
       words: 3076
      flesch: 50
     summary: Low risk patients (no recent travel, contact with COVID-19 patient or fever/respiratory symptoms) underwent surgery in the main OR however anesthetic staff-maintained use of N95 respirators for intubation with standard PPE for surgeons. Early co-ordination with the ID, ER, OR, porters and cleaning departments were able to protocolise the movement of suspect COVID-19 patients to limit staff exposure.
    keywords: care; covid-19; eacs; patients; service; staff; surgery; team
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        item: #4427 of 7819
          id: cord-310455-asu17dea
      author: Binkin, Nancy
       title: Protecting our health care workers while protecting our communities during the COVID-19 pandemic: a comparison of approaches and early outcomes in two Italian regions, Italy, 2020
        date: 2020-04-14
       words: 4214
      flesch: 46
     summary: In other countries such as the United States, where health care is privatized, and integration with public health services is limited, it nonetheless may be possible to implement most of the major components in specific settings. Methods We used numerator and denominator data from public Italian government sources to calculate reported rates of COVID-19 testing/1000, COVID-19 cases/100,000 overall and for health care workers (HCWs) and non-HCWs, deaths per 100,000, and the percent of cases admitted to hospitals and ICUs for February 24-April 1, 2020.
    keywords: care; cases; covid-19; hcws; health; lombardy; preprint; public; veneto
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        item: #4428 of 7819
          id: cord-310457-l3d1dc93
      author: Robinson, A. J.
       title: A modification to the Maquet Flow-i anaesthesia machinefor ICU ventilation
        date: 2020-04-11
       words: 3090
      flesch: 53
     summary: https://doi.org/10.1101/2020.04.06.20054882 doi: medRxiv preprint single patient use. While anaesthesia machines are able to run for short periods of time without scavenging, they are designed to be used with a constant low-level vacuum applied via the Anaesthesia Gas Scavenging (AGS) port and in a positive pressure Operating Room environment.
    keywords: flow; license; machine; patient; preprint; system
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        item: #4429 of 7819
          id: cord-310465-2ahfxd9c
      author: Martinez, David
       title: COVID’s Impact on Radiation Oncology: A Latin American Survey Study
        date: 2020-10-01
       words: 2205
      flesch: 41
     summary: Follow-up surveys will be performed to provide dynamic monitoring the pandemic’s impact on radiation therapy services and adoption of ameliorating measures. 9, 10 Knowing the current real impact of the COVID-19 pandemic on radiation therapy services across the region might yield insights for cancer control policy.
    keywords: covid-19; impact; pandemic; patients; radiation; treatment
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        item: #4430 of 7819
          id: cord-310507-5h6egve4
      author: van Doorn, Amarylle S.
       title: Systematic review with meta‐analysis: SARS‐CoV‐2 stool testing and the potential for faecal‐oral transmission
        date: 2020-08-27
       words: 3540
      flesch: 36
     summary: However, there is a growing body of studies in which SARS-CoV-2 RNA was detected in stool samples (including anal swabs) from COVID-19 patients. Pediatr Infect Dis J Review article: gastrointestinal features in COVID-19 and the possibility of faecal transmission Three cases of novel coronavirus pneumonia with viral nucleic acids still positive in stool after throat swab detection turned negative Clinical features of children with SARS-CoV-2 infection: an analysis of 13 cases from Changsha, China Detection of SARS-CoV-2 in Different Types of Clinical Specimens Detection and analysis of nucleic acid in various biological samples of COVID-19 patients Isolation of 2019-nCoV from a Stool Specimen of a Laboratory-Confirmed Case of the Coronavirus Disease 2019 (COVID-19) Virus shedding patterns in nasopharyngeal and fecal specimens of COVID-19 patients.
    keywords: coronavirus; cov-2; covid-19; patients; samples; sars; specimens; stool; studies
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        item: #4431 of 7819
          id: cord-310534-ng6321hh
      author: Kaushik, Ashlesha
       title: COVID-19 in Children: Clinical Approach and Management- Correspondence
        date: 2020-07-08
       words: 1389
      flesch: 39
     summary: E-mail: rlodha1661@gmail.com COVID-19 in children: clinical approach and management Compassionate use of remdesivir for patients with severe covid-19 Multicenter initial guidance on use of antivirals for children with COVID-19/SARS-CoV-2 A trial of lopinavir-ritonavir in adults hospitalized with severe COVID-19 Race to find COVID-19 treatments accelerates Convalescent plasma as a potential therapy for COVID-19 Effective treatment of severe COVID-19 patients with tocilizumab COVID-19 in children: Clinical approach and management Experts Shed More Light on COVID-19-Related Inflammatory Syndrome in Children Pathophysiology of COVID-19: Why children fare better than adults? We had suggested exclusive breastfeeding for all neonates born to COVID-19 mothers [1] .
    keywords: children; covid-19; management; patients
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        item: #4432 of 7819
          id: cord-310539-8zk3hkgj
      author: Barengolts, Elena
       title: PERSEVERE OR PERIL: DIABETES CARE IN TIMES OF COVID-19
        date: 2020-08-08
       words: 1942
      flesch: 42
     summary: The other therapies in trials include convalescent plasma (from COVID-19 recovered patients), anti-angiogenic (bevacizumab), thalidomide, and modifiers of the gut microbiome (7) . However, in a retrospective cohort analysis of more than 500,000 adults, only ~30% and ~20% among DM patients had flu and pneumococcal vaccines, respectively, far below the recommendations (11) .
    keywords: coronavirus; covid-19; diabetes; mortality; patients
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        item: #4433 of 7819
          id: cord-310540-pnb8sr58
      author: Novotny, J. S.
       title: Association between stress and depressive symptoms and the Covid-19 pandemic
        date: 2020-07-29
       words: 3680
      flesch: 48
     summary: We found no significant difference in gains of stress levels or depressive symptoms between those who spent the quarantine alone or with others (stress level: P=0.77; severity of depressive symptoms: P=0.33). Feeling of loneliness during Covid-19 pandemic had the greatest impact on increased stress levels and depressive symptoms.
    keywords: author; covid-19; medrxiv; perpetuity; preprint; stress; symptoms
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        item: #4434 of 7819
          id: cord-310555-nhnhst3f
      author: Morgan, Randall C.
       title: On Answering the Call to Action for COVID-19: Continuing a Bold Legacy of Health Advocacy
        date: 2020-07-22
       words: 3475
      flesch: 32
     summary: A ll leading professional medical organizations and associations in the United States and especially those related to public health should feel secure taking bold action to measurably advance health equity within our country amid the current pandemic due to the virus that causes COVID-19. Plans to address public health emergencies like an epidemic may be drafted and possibly rehearsed for the public are seldomly written with attention to the complexity of the needs and barriers for specific populations.
    keywords: americans; black; communities; coronavirus; covid-19; disease; health; pandemic; public
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        item: #4435 of 7819
          id: cord-310561-67kp743f
      author: Shah, Akshay
       title: Systemic hypoferremia and severity of hypoxemic respiratory failure in COVID-19
        date: 2020-06-09
       words: 972
      flesch: 46
     summary: Therefore, we sought to characterise iron parameters, including serum iron, in COVID-19 intensive care unit (ICU) patients and relate these to disease severity. Compared with patients with non-severe hypoxemia, patients with severe hypoxemia had significantly lower levels of serum iron (median 2.3 (IQR, 2.2-2.5) vs 4.3 (IQR, 3.3-5.2) μmol/L, p < 0.001) and lymphocyte counts (mean (SD) 0.50 (0.2) vs. 0.87 (0.4), p = 0.0152).
    keywords: covid-19; iron; patients; serum
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        item: #4436 of 7819
          id: cord-310594-i0586vfw
      author: Weemaes, Matthias
       title: Laboratory information system requirements to manage the COVID-19 pandemic: a report from the Belgian national reference testing center
        date: 2020-04-29
       words: 2542
      flesch: 26
     summary: Therefore, clinical laboratories face specific challenges that require dedicated LIS functionality to ensure safe, reliable testing and acceptable turn-around-times. Samples were sent to the reference laboratory from across Belgium, and once analyzed results were reported to referring clinical laboratories as well as hospitals and primary care physicians.
    keywords: clinical; covid-19; data; laboratory; lis; reporting; sars; testing
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        item: #4437 of 7819
          id: cord-310605-r63sg73c
      author: Dorward, D. A.
       title: Tissue-specific tolerance in fatal Covid-19
        date: 2020-07-04
       words: 4484
      flesch: 31
     summary: A marked increase in the number of plasma cells (10% or more) was seen in 7/8 bone marrow trephines but these plasma cells had a normal phenotype, being negative for CD56 and cyclin D1, and were polytypic with light chain immunohistochemistry. Splenic red pulp was congested and, in all cases, contained an increased number of plasma cells with similar features to those observed in mediastinal nodes.
    keywords: cells; cov-2; covid-19; inflammation; lung; presence; sars; tissue; viral
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        item: #4438 of 7819
          id: cord-310623-zbjgr9jk
      author: Ellington, Sascha
       title: Characteristics of Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status — United States, January 22–June 7, 2020
        date: 2020-06-26
       words: 2998
      flesch: 37
     summary: Symptomatic pregnant and nonpregnant women with COVID-19 reported similar frequencies of cough (>50%) and shortness of breath (30%), but pregnant women less frequently reported headache, muscle aches, fever, chills, and diarrhea. Chronic lung disease, diabetes mellitus, and cardiovascular disease were more commonly reported among pregnant women than among nonpregnant women.
    keywords: covid-19; pregnancy; pregnant; women
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        item: #4439 of 7819
          id: cord-310636-y7n22ykt
      author: Garcia-Beltran, W. F.
       title: COVID-19 neutralizing antibodies predict disease severity and survival
        date: 2020-10-20
       words: 10932
      flesch: 37
     summary: Here we found that severely ill COVID-19 patients had the highest levels of anti-RBD antibodies, which other studies have similarly described (Shrock et al. , 2020) . Remarkably, we find that anti-RBD antibody levels, neutralization titer, and neutralization potency index predicted disease severity and survival, yet lacked cross-neutralizing activity to pre-emergent WIV1-CoV. Taken together, our results highlight the impact of an effective humoral immune response on COVID-19, as quantified by a neutralization potency index, and describe the A cross-sectional cohort of 113 COVID-19 cases confirmed by SARS-CoV-2 nasopharyngeal PCR was studied and followed for at least 3 months.
    keywords: antibodies; antibody; coronavirus; cov-2; covid-19; figure; igg; levels; license; medrxiv; neutralization; patients; preprint; rbd; sars; spike
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        item: #4440 of 7819
          id: cord-310650-8lhkiw9p
      author: Gamble, Anissa
       title: The Challenges of COVID-19 for People Living With Diabetes: Considerations for Digital Health
        date: 2020-05-15
       words: 2089
      flesch: 40
     summary: Despite the positive enablers for remote diabetes care, the ability to share diabetes device data back to the clinic remains a challenge [46] . It continues to be a challenge to convince manufacturers of diabetes devices and EHR vendors to create truly interoperable systems to ease the burden on the diabetes communities
    keywords: care; covid-19; diabetes; health; pandemic; people
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        item: #4441 of 7819
          id: cord-310661-hrvuhkq9
      author: Patell, Rushad
       title: Incidence of thrombosis and hemorrhage in hospitalized cancer patients with COVID‐19
        date: 2020-07-21
       words: 3382
      flesch: 37
     summary: This article is protected by copyright Factors at admission associated with bleeding risk in medical patients: findings from the IMPROVE investigators Definition of clinically relevant non-major bleeding in studies of anticoagulants in atrial fibrillation and venous thromboembolic disease in non-surgical patients: communication from the SSC of the ISTH Biased estimation of thrombosis rates in cancer studies using the method of Kaplan and Meier Thromboembolism in hospitalized neutropenic cancer patients Predicting risk of venous thromboembolism in hospitalized cancer patients: Utility of a risk assessment tool Prevention of venous thromboembolism in medical patients with enoxaparin: a subgroup analysis of the MEDENOX study Thromboprophylaxis with dalteparin in medical patients: which patients benefit? key: cord-310661-hrvuhkq9 authors: Patell, Rushad; Bogue, Thomas; Bindal, Poorva; Koshy, Anita; Merrill, Mwanasha; Aird, William C; Bauer, Kenneth A; Zwicker, Jeffrey I title: Incidence of thrombosis and hemorrhage in hospitalized cancer patients with COVID‐19 date: 2020-07-21 journal: J Thromb Haemost DOI: 10.1111/jth.15018 sha: doc_id: 310661 cord_uid: hrvuhkq9 BACKGROUND:
    keywords: cancer; cohort; covid-19; events; incidence; patients; thrombosis
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        item: #4442 of 7819
          id: cord-310691-6danlh8h
      author: Ma, Simin
       title: Clinical Characteristics of Critically Ill Patients Co-infected with SARS-CoV-2 and the Influenza Virus in Wuhan, China
        date: 2020-05-26
       words: 2298
      flesch: 46
     summary: The results showed a high proportion of COVID-19 patients were co-infected with influenza in Tongji Hospital, with no significant difference in the proportion of co-infection between survivors and non-survivors. Studies have reported that elevated D-dimer levels are a risk factor for death in COVID-19 patients (Wu et al. 2020a; Zhou et al. 2020) .
    keywords: covid-19; influenza; patients; survivors; virus
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        item: #4443 of 7819
          id: cord-310697-zszexapf
      author: Morlacco, Alessandro
       title: The multifaceted long-term effects of the COVID-19 pandemic on urology
        date: 2020-05-06
       words: 2044
      flesch: 37
     summary: Moreover, guidelines on urological urgencies could be improved and made more accessible to family physicians to enhance their involvement in urological care. Finally, while every health-care system has its own peculiarities, non-medical providers with specific urological training could be empowered further to optimize the organization of urological care.
    keywords: care; covid-19; pandemic; patients; urology
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        item: #4444 of 7819
          id: cord-310738-fnsf2qqm
      author: Yalcin Bahat, Pinar
       title: Micronutrients in COVID-19 Positive Pregnancies
        date: 2020-09-23
       words: 2607
      flesch: 48
     summary: Access Immunoassay System (© 2020Beckman Coulter Inc., Brea, CA, USA) was used to quantitate serum vitamin B12 levels. Tubes were submitted to the hospital's central laboratory for determination of 25(OH)D, zinc, and vitamin B12 levels.
    keywords: 25(oh)d; covid-19; levels; serum; study; vitamin; zinc
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        item: #4445 of 7819
          id: cord-310740-7dong29x
      author: Alkeridy, Walid A.
       title: Reply to: Neurological, Cognitive and Behavioral Disorders During COVID‐19: The Nitric Oxide Track
        date: 2020-06-24
       words: 622
      flesch: 21
     summary: They propose an intriguing mechanism for cognitive impairment related to coronavirus disease 2019 . 6, 7 Whether the nitric oxide track will prove to have a central role in the acute manifestations of COVID-19related cognitive impairment remains to be seen.
    keywords: covid-19; delirium
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        item: #4446 of 7819
          id: cord-310753-sv88b0dt
      author: Marks, M.
       title: Transmission of COVID-19 in 282 clusters in Catalonia, Spain: a cohort study
        date: 2020-10-27
       words: 3591
      flesch: 47
     summary: key: cord-310753-sv88b0dt authors: Marks, M.; Millat, P.; Ouchi, D.; Roberts, C. h.; Alemany, A.; Corbacho-Monne, M.; Ubals, M.; Vall-Mayans, M.; Gonzalez Beiras, C.; Prat, N.; Ara, J.; Clotet, B.; Mitja, O. title: Transmission of COVID-19 in 282 clusters in Catalonia, Spain: a cohort study date: 2020-10-27 journal: nan DOI: 10.1101/2020.10.27.20220277 sha: doc_id: 310753 cord_uid: sv88b0dt Background There remains limited data on what variables affect the risk of transmission of SARS-CoV-2 and developing symptomatic Covid-19 and in particular the relationship to viral load (VL). The risk of symptomatic Covid-19 is strongly associated with viral load of the contact at baseline, which shortens the incubation time in a dose-dependent manner.
    keywords: license; load; preprint; risk; transmission
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        item: #4447 of 7819
          id: cord-310762-3clh1zv6
      author: Azanza Ricardo, C. L.
       title: The Risk of Lifting COVID-19 Confinement in Mexico
        date: 2020-06-02
       words: 1715
      flesch: 50
     summary: Assuming the most optimistic scenario by our predictions, the smallest number of new COVID-19 cases, Mexico would require at least a 3 fold increase in hospital capacities dedicated for COVID-19. Furthermore, 147 the data of infected cases in Mexico is very limited because of application of the sentinel model.
    keywords: cases; confinement; covid-19; mexico
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        item: #4448 of 7819
          id: cord-310769-y6orh217
      author: Zaman, A.
       title: The Relationship between Deteriorating Mental Health Conditions and Longitudinal Behavioral Changes in Google and YouTube Usages among College Students in the United States during COVID-19: Observational Study
        date: 2020-08-25
       words: 6617
      flesch: 44
     summary: On one hand, online engagements can cause fluctuations in mental health. It has been widely applied in researches involving social media and mental health.
    keywords: anxiety; behavior; covid-19; data; dep; depression; google; group; health; non; outbreak; search; youtube
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        item: #4449 of 7819
          id: cord-310776-4iqu18gi
      author: Supady, Alexander
       title: Extracorporeal cytokine adsorption as an alternative to pharmacological inhibition of IL-6 in COVID-19
        date: 2020-08-20
       words: 546
      flesch: 22
     summary: key: cord-310776-4iqu18gi authors: Supady, Alexander; Duerschmied, Daniel; Bode, Christoph; Rieder, Marina; Lother, Achim title: Extracorporeal cytokine adsorption as an alternative to pharmacological inhibition of IL-6 in COVID-19 date: 2020-08-20 journal: Crit Care DOI: 10.1186/s13054-020-03238-1 sha: doc_id: 310776 cord_uid: 4iqu18gi nan Extracorporeal cytokine adsorption as an alternative to pharmacological inhibition of IL-6 in COVID-19 Alexander Supady 1,2,3* , Daniel Duerschmied 1,2 , Christoph Bode 1,2 , Marina Rieder 1,2 and Achim Lother 1, 2, 4 With great interest we read the article by Convertino et Following initial reports describing Interleukin-6 (IL-6) as a predictive factor for a negative outcome, extracorporeal cytokine adsorption was discussed as a possible treatment option for severe COVID-19 cases.
    keywords: covid-19; cytokine
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        item: #4450 of 7819
          id: cord-310779-4puiao40
      author: Mehta, Pooja
       title: Telehealth and Nutrition Support During the Covid-19 Pandemic
        date: 2020-07-14
       words: 2357
      flesch: 46
     summary: Thus it is not surprising that slow 111 internet connection and poor connection to wireless networks negatively impacts communication 112 between health care providers and patients during telehealth visits. 40 One-on-one visits 42 Perhaps one of the most intuitive first steps in using telehealth is to transform existing 43 outpatient one-on-one visits to telehealth visits with an RDN.
    keywords: care; covid-19; pandemic; patients; providers; telehealth; visits
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        item: #4451 of 7819
          id: cord-310803-iig414jg
      author: Khazeei Tabari, Mohammad Amin
       title: Applying Computer Simulations in Battling with COVID-19, using pre-analyzed molecular and chemical data to face the pandemic
        date: 2020-10-17
       words: 1344
      flesch: 25
     summary: Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic 27 implications Ro 90-7501 Is a Novel 29 Radiosensitizer for Cervical Cancer Cells that Inhibits ATM Phosphorylation Diagnosis of Alzheimer's disease utilizing amyloid and 32 tau as fluid biomarkers Global research on coronavirus disease (COVID-19) Model Database SWISS-40 MODEL: homology modelling of protein structures and complexes SWISS-MODEL: 43 modelling protein tertiary and quaternary structure using evolutionary information UniProt: a worldwide hub of protein knowledge Chloroquine dosing recommendations for pediatric COVID-19 2 supported by modeling and simulation Identification of Potential Binders of the Main 4 Protease 3CL(pro) of the COVID-19 via Structure-Based Ligand Design and Molecular Modeling Optimizing hydroxychloroquine dosing for patients with COVID-19: An integrative modeling 8 approach for effective drug repurposing Pharmacologic treatments for 10 coronavirus disease 2019 (COVID-19): a review This study was supported by Molecular and Cell Biology Research Center, Mazandaran University of Medical Sciences, Sari, Iran (Grant number: 7640). It is the third pathogenic and transmittable virus after previous outbreaks for this 6 family, including severe acute respiratory syndrome (SARS) and the Middle East respiratory 7 syndrome (MERS).
    keywords: coronavirus; cov-2; covid-19; covs; protein; sars
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        item: #4452 of 7819
          id: cord-310809-z0isuuui
      author: Simpson, Alexander I. F.
       title: Management of COVID-19 Response in a Secure Forensic Mental Health Setting
        date: 2020-06-23
       words: 3570
      flesch: 48
     summary: Third, the long-term hospitalization of forensic patients is often a result of serious risk to their own health and safety or that of others. Some of these issues may overlap with the contained, vulnerable patient populations in long-term care facilities; however, an important point of difference is that patients in the care of long-term care facilities often have limited mobility, while forensic patients are usually mobile, and sometimes behaviorally disturbed, requiring physical intervention from staff to manage their risk of harm to themselves or others.
    keywords: covid-19; health; isolation; outbreak; patients; staff; unit
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        item: #4453 of 7819
          id: cord-310857-i9v9antx
      author: Blaisdell, Laura L.
       title: Preventing and Mitigating SARS-CoV-2 Transmission — Four Overnight Camps, Maine, June–August 2020
        date: 2020-09-04
       words: 2588
      flesch: 40
     summary: During June-August, the combined attendance of the four camps included 642 children and 380 staff members, aged 7-70 years, from 41 states with a variety of 7-day average rate of SARS-CoV-2 infection (Figure) ; 1.8% of camp attendees ¶ ¶ (10 staff members and eight campers) came from six international locations (Bermuda, Canada, Mexico, South Africa, Spain, and United Kingdom) and Puerto Rico (Table 1) . has important implications for similar congregate settings such as day camps and schools with the same age range.
    keywords: attendees; camp; cov-2; sars; staff; test
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        item: #4454 of 7819
          id: cord-310862-53g4hjtp
      author: DeFilippis, Ersilia M.
       title: Challenges in Heart Transplantation in the Era of COVID-19
        date: 2020-04-21
       words: 856
      flesch: 37
     summary: As a community, we have a responsibility to share information in real time, gather more research, and provide guidance to other transplant providers, our multidisciplinary teams, and patients. For HT patients admitted with COVID-19 infection, some have advocated for reduced immunosuppression and moderate-dose IV steroids.
    keywords: covid-19; patients; transplant
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        item: #4455 of 7819
          id: cord-310868-rqmny4r2
      author: Tesfaye, Wubshet
       title: How Do We Combat Bogus Medicines in the Age of the COVID-19 Pandemic?
        date: 2020-08-18
       words: 2868
      flesch: 30
     summary: More importantly, it is imperative medicines regulatory authorities and relevant stakeholders implement robust authentication and procurement processes to ensure quality medicines supply. The prevalence of falsified medicines spans from 1% in developed settings to 10% in the Global South.
    keywords: covid-19; global; health; medicines; pandemic; products; substandard; supply
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        item: #4456 of 7819
          id: cord-310891-yfouizjb
      author: Korada, Sai Krishna C.
       title: Management of COVID-19 in a Durable Left Ventricular Assist Device Recipient: A Continuity of Care Perspective
        date: 2020-08-20
       words: 1870
      flesch: 39
     summary: 1 Hypertension, diabetes, and cardiovascular disease increase the risk of adverse outcomes with COVID-19 infection. Management of COVID-19 infection has largely been guided by standard respiratory care, case reports, expert opinion, small randomized clinical trials, and prior experience with SARS-CoV-1, MERS, and H1N1.
    keywords: covid-19; disease; infection; lvad; management; patient
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        item: #4457 of 7819
          id: cord-310895-zkzew0kb
      author: Periyakaruppan, Muthiah
       title: COVID Abdomen: SARS-CoV-2 Infection Presenting as ‘Acute Abdomen’ in a Child
        date: 2020-09-23
       words: 551
      flesch: 44
     summary: [4] reported the importance of chest CT evaluation in addition to abdominal CT in patients presenting as acute abdomen to identify basal pneumonia to ignite a suspicion of COVID-19, not as a primary acute abdomen presentation. Covid-19: concerns grow over inflammatory syndrome emerging in children Epidemiology of COVID-19 among children in China Children with Covid-19 in pediatric emergency departments in Italy Role of chest CT in patients with acute abdomen during the COVID-19 era COVID-19 associated multisystem inflammatory syndrome in children (MIS-C) guidelines, a Western New York approach Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Conflict of Interest None.
    keywords: abdomen; covid-19
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        item: #4458 of 7819
          id: cord-310901-oooat8xj
      author: Arca, Karissa N.
       title: COVID‐19 and Headache Medicine: A Narrative Review of Non‐Steroidal Anti‐Inflammatory Drug (NSAID) and Corticosteroid Use
        date: 2020-07-10
       words: 4431
      flesch: 39
     summary: The risks or benefits of steroid use during the COVID-19 pandemic may be dependent on the timing of administration during the disease course. Comparing the data regarding steroid use from prior viral outbreaks and the information available from the current pandemic, it remains unclear if steroids offer benefit or harm when administered to patients with COVID-19.
    keywords: coronavirus; covid-19; headache; nsaids; pandemic; patients; respiratory; risk; steroids; treatment; use
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        item: #4459 of 7819
          id: cord-310902-cfci8lef
      author: Freites Nuñez, Dalifer D
       title: Risk factors for hospital admissions related to COVID-19 in patients with autoimmune inflammatory rheumatic diseases
        date: 2020-08-07
       words: 3989
      flesch: 39
     summary: To describe patients with autoimmune inflammatory rheumatic diseases (AIRD) who had COVID-19 disease; to compare patients who required hospital admission with those who did not and assess risk factors for hospital admission related to COVID-19. The incidence and severity of COVID-19 disease seem to be higher in patients with risk factors, such as advanced age and associated comorbidities, mainly hypertension, diabetes, heart disease and previous respiratory diseases.
    keywords: admission; age; covid-19; data; disease; hospital; patients; risk; study
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        item: #4460 of 7819
          id: cord-310944-tfn0ltrz
      author: Peck, Jessica L.
       title: COVID 19: Impacts and Implications for Pediatric Practice
        date: 2020-07-09
       words: 5794
      flesch: 42
     summary: a. Use expired 3M N-95 masks for low-risk exposures* b. Removal, disinfection, and reuse of PPE is preferred over extended single periods of use c. Ideal PPE for COVID-19 care includes a new N-95 mask, gown, medical grade surgical gloves, and eye covers and/or a face shield* d. Visitors to the healthcare setting should be limited* There is much work to be done to ensure equitable access for all to COVID-19 related care (Relman et al., 2020) .
    keywords: care; cdc; children; coronavirus; covid-19; health; healthcare; pandemic; pediatric; persons; risk; spread; testing; transmission
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        item: #4461 of 7819
          id: cord-310961-e1mb7uuh
      author: Nouvenne, Antonio
       title: Point-of-care chest ultrasonography as a diagnostic resource for COVID-19 outbreak in nursing homes
        date: 2020-05-25
       words: 1159
      flesch: 39
     summary: Conclusions and implications In nursing home residents, screening of COVID-19 pneumonia with bedside chest ultrasonography is feasible and may represent a valid diagnostic aid for an early detection of COVID-19 outbreaks and adequate patient management. Thus, in older multimorbid nursing home 56 residents with mild/moderate respiratory symptoms or fever, chest ultrasound could help clinicians 57 to gain important diagnostic information, prioritize the access to SARS-CoV-2 testing, and avoid 58 many hospital admissions.
    keywords: chest; covid-19; nursing; ultrasound
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        item: #4462 of 7819
          id: cord-310974-hz37yf39
      author: Crolley, Valerie E.
       title: COVID-19 in cancer patients on systemic anti-cancer therapies: outcomes from the CAPITOL (COVID-19 Cancer PatIenT Outcomes in North London) cohort study
        date: 2020-10-23
       words: 3542
      flesch: 43
     summary: Alternatively, other studies found that treatment with immunotherapy did not impact mortality negatively in COVID-19 positive cancer patients, 11 and it is hypothesised that immunotherapy may reduce the risk of developing the cytokine storm primarily responsible for the development of ARDS in COVID-19. COVID-19 patients who had received chemotherapy were not more likely to be admitted to ICU (adj.
    keywords: cancer; covid-19; outcomes; patients; risk; study; treatment
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        item: #4463 of 7819
          id: cord-310996-ihs9xbv8
      author: Stang, Andreas
       title: Characteristics of COVID-19 pandemic and public health consequences
        date: 2020-04-24
       words: 852
      flesch: 51
     summary: The infection rate is substantially underestimated because a significant proportion of COVID-19 patients have not been confirmed by polymerase chain reaction (PCR) since many patients, especially younger ones, have only few symptoms if any, and many patients with symptoms are not tested at all. A cross-sectional analysis of the number of ICU patients on April 19, 2020, revealed that overall 2889 patients were currently ICU patients with 2113 (73%) undergoing artificial ventilation.
    keywords: age; patients
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        item: #4464 of 7819
          id: cord-310997-ulgemn42
      author: Swai, Joel
       title: Letter to the editor—Mortality rate of acute kidney injury in SARS, MERS, and COVID-19 infection: a systematic review and meta-analysis
        date: 2020-09-11
       words: 789
      flesch: 52
     summary: [6] , future large meta-analyses may be suggested to explore the clinical impacts from different races in AKI mortality in COVID-19 patients. key: cord-310997-ulgemn42 authors: Swai, Joel title: Letter to the editor—Mortality rate of acute kidney injury in SARS, MERS, and COVID-19 infection: a systematic review and meta-analysis date: 2020-09-11 journal: Crit Care DOI: 10.1186/s13054-020-03239-0 sha: doc_id: 310997 cord_uid: ulgemn42 nan Letter to the editor-Mortality rate of acute kidney injury in SARS, MERS, and COVID-19 infection: a systematic review and metaanalysis Joel Swai *
    keywords: covid-19; mortality
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        item: #4465 of 7819
          id: cord-310998-zchtu6cm
      author: Kalash, Danny A.
       title: How COVID-19 Deepens Child Oral Health Inequities
        date: 2020-05-23
       words: 1332
      flesch: 42
     summary: 5 By abruptly pausing the provision of child dental care, COVID-19 adds delays to time-sensitive treatment, worsens the status of already significant decay, and further overburdens our previously strained dental safety net including community health centers, federally qualified health centers, and hospitals. 6 COVID-19's spread refocuses our attention to those social inequities, perpetuated by deficient federal and state policies, which carry both direct and unintended consequences for child oral health.
    keywords: children; covid-19; families; health
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        item: #4466 of 7819
          id: cord-310999-6xef9z2w
      author: Chen, Yiting
       title: In the big picture of COVID-19 pandemic: what can sleep do
        date: 2020-06-10
       words: 475
      flesch: 48
     summary: Additionally, when exposed to COVID-19 infection, a series of pro-inflammatory cytokines were activated, increasing the risk of developing a cytokine storm [3] . Furthermore, it is recommended that medical professionals educate the public on how to develop good sleep habits in order to help people to respond to this pandemic more effectively.
    keywords: covid-19; sleep
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        item: #4467 of 7819
          id: cord-311026-mpr3xb2a
      author: Petersen, Eskild
       title: COVID-19–We urgently need to start developing an exit strategy
        date: 2020-04-29
       words: 5634
      flesch: 51
     summary: A study comparing health care systems in Hong Kong, Singapore and Japan had three important conclusions [Legido-Quigley et al. 2020 ]. Over half of the non-imported cases could be traced back to their close contacts with reported local cases.
    keywords: cases; countries; covid-19; evaluation; file; health; novapdf; pdf; quarantine; testing; transmission
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        item: #4468 of 7819
          id: cord-311029-x0lk4110
      author: Palermo, Sara
       title: Covid-19 Pandemic: Maximizing Future Vaccination Treatments Considering Aging and Frailty
        date: 2020-09-18
       words: 6416
      flesch: 33
     summary: Indeed, if any cross-reactive epitopes were identified between COVID-19 and SARS-CoV, previous vaccine for SARS-CoV might be re-utilized to facilitate COVID-19 vaccine development (65) . [(72) , p. 234], strategies to improve vaccine uptake can target all the components underpinning low coverage, and include technology and communication-based strategies, physician-centered approaches, targeting healthcare workers for influenza vaccination, systembased factors, improved vaccine efficacy, and above all, political will and leadership.
    keywords: adherence; age; aging; covid-19; elderly; frailty; health; immune; people; population; sars; system; vaccination; vaccine
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        item: #4469 of 7819
          id: cord-311030-k42iqh40
      author: Kvasnovsky, Charlotte L
       title: Limiting operations for acute appendicitis in children: lessons learned from the U.S. epicenter of the COVID-19 pandemic()
        date: 2020-06-23
       words: 3169
      flesch: 38
     summary: RESULTS: 45.5% of children (25/55) with acute appendicitis underwent NOM. key: cord-311030-k42iqh40 authors: Kvasnovsky, Charlotte L; Shi, Yan; Rich, Barrie S; Glick, Richard; Soffer, Sam; Lipskar, Aaron M; Dolgin, Stephen; Bagrodia, Naina; Hong, Andrew; Prince, Jose M; James, Douglas; Sathya, Chethan title: Limiting operations for acute appendicitis in children: lessons learned from the U.S. epicenter of the COVID-19 pandemic() date: 2020-06-23 journal: J Pediatr Surg DOI: 10.1016/j.jpedsurg.2020.06.024 sha: doc_id: 311030 cord_uid: k42iqh40 INTRODUCTION:
    keywords: appendicitis; children; covid-19; nom; pandemic; patients
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        item: #4470 of 7819
          id: cord-311043-nidu7om2
      author: Erdinc, Burak
       title: Spontaneous Retroperitoneal Bleed Coincided With Massive Acute Deep Vein Thrombosis as Initial Presentation of COVID-19
        date: 2020-08-15
       words: 2083
      flesch: 42
     summary: A pneumonia outbreak associated with a new coronavirus of probable bat origin Hypercoagulability of COVID-19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Thrombosis in hospitalized patients with COVID-19 in a New York City Health System Autopsy findings and venous thromboembolism in patients with COVID-19 {Epub ahead of print Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19 COVID and coagulation: bleeding and thrombotic manifestations of SARS-CoV2 infection Coagulation abnormalities and thrombosis in patients with Here we present a case of COVID-19 infection that reports both thrombosis and bleeding.
    keywords: acute; bleeding; covid-19; dic; patients; thrombosis
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        item: #4471 of 7819
          id: cord-311044-kjx0z1hc
      author: Rubio-Pérez, Inés
       title: COVID-19: key concepts for the surgeon
        date: 2020-05-28
       words: 4654
      flesch: 47
     summary: Surgical specialists are facing an unprecedented situation: they must collaborate in the ER or medical wards attending these patients, while still needing to make decisions about surgical patients with probable COVID-19. Several cases of atypical pneumonia of unclear origin were detected.
    keywords: cases; cov-2; covid-19; disease; health; patients; risk; sars; symptoms; treatment; virus
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        item: #4472 of 7819
          id: cord-311054-dwns5l64
      author: Rafiq, Danish
       title: Evaluation and prediction of COVID-19 in India: a case study of worst hit states
        date: 2020-06-19
       words: 2171
      flesch: 52
     summary: A systematic review and meta-analysis Coronavirus: covid-19 has killed more people than SARS and MERS combined, despite lower case fatality rate Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, The lancet Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Early dynamics of transmission and control of COVID-19: a mathematical modelling study Prediction of the epidemic peak of coronavirus disease in Japan Forecasting the Spread of COVID-19 in Kuwait Using Compartmental and Logistic Regression Models A model based study on the dynamics of COVID-19: Prediction and control Mathematical Modeling of COVID-19 Transmission Dynamics with a Case Study of Wuhan Prediction for the spread of COVID-19 in India and effectiveness of preventive measures A machine learning methodology for real-time forecasting of the 2019-2020 COVID-19 outbreak using Internet searches, news alerts, and estimates from mechanistic models Modeling and Forecasting for the number of cases of the COVID-19 pandemic with the Curve Estimation Models, the Box-Jenkins and Exponential Smoothing Methods Optimization method for forecasting confirmed cases of COVID-19 in China On The Consistency of Prediction Error Identification Methods Dynamical effects of overparametrization in nonlinear models Improved structure selection for nonlinear models based on term clustering System Identification -Theory For the User, Appendix 4A Method for the Solution of Certain Problems in Least-Squares Algorithm for Least-squares Estimation of Nonlinear Parameters The Levenberg-Marquardt Algorithm: For example, in [12] , a data-driven estimation method like long short-term memory (LSTM) is used for the prediction of total number of COVID-19 cases in India for a 30-days ahead prediction window.
    keywords: cases; covid-19; india; model; number; spread
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        item: #4473 of 7819
          id: cord-311074-j3fw4dfc
      author: Alviset, Sophie
       title: Continuous Positive Airway Pressure (CPAP) face-mask ventilation is an easy and cheap option to manage a massive influx of patients presenting acute respiratory failure during the SARS-CoV-2 outbreak: A retrospective cohort study
        date: 2020-10-14
       words: 4848
      flesch: 44
     summary: Optimal respiratory support for COVID-19 patients presenting with acute hypoxemic respiratory failure, however, remains unknown. The role of face-mask CPAP in managing acute hypoxemic respiratory failure in COVID-19 patients warrants further investigation in larger prospective studies and comparison with other ways to manage hypoxemic respiratory failure, such as high flow nasal oxygen cannula
    keywords: covid-19; cpap; failure; hypoxemic; icu; intubation; patients; respiratory; study; ventilation
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        item: #4474 of 7819
          id: cord-311081-fsnthvrq
      author: García, Laura Fernández
       title: RELACIÓN ENTRE OBESIDAD, DIABETES E INGRESO EN UCI EN PACIENTES COVID-19
        date: 2020-06-25
       words: 928
      flesch: 54
     summary: En cuanto a la obesidad, varios estudios realizados en China, Italia, y EE.UU., han descrito que esta población presenta mayor probabilidad de infectarse por el virus, de desarrollar neumonías más graves, complicaciones y muerte; así como mayor riesgo de aparición de una cepa más virulenta y de prolongar el tiempo de contagio al resto de población (2) . La obesidad como factor de riesgo y factor predictivo de severidad de la infección por COVID-19 está siendo descrita por algunos estudios, pero aún hay gran falta de evidencia.
    keywords: con; covid-19; que
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        item: #4475 of 7819
          id: cord-311082-sspcz9t6
      author: Chen, Shi
       title: Four Challenges Associated With Current Mathematical Modeling Paradigm of Infectious Diseases and Call for a Shift
        date: 2020-08-07
       words: 1528
      flesch: 31
     summary: SEIR models are mechanistic models developed almost a century ago [3] . Second, SEIR models are formulated at the population level.
    keywords: covid-19; modeling; models; seir
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        item: #4476 of 7819
          id: cord-311085-jmuyi53x
      author: Saqlain, Muhammad
       title: Is Pakistan prepared to tackle the coronavirus epidemic?
        date: 2020-03-20
       words: 1215
      flesch: 56
     summary: Pakistan borders countries infected with COVID-19, including China, an epicenter of the disease that currently has the highest number of deaths attributed to COVID-19 (n = 3162), to the north, and Iran, a country with the third highest number of COVID-19-associated mortalities (n = 291), to the west; Italy has the second highest number of deaths [3] . After declaration of the COVID-19 epidemic, the Pakistan government took several measures to cope with this zoonotic illness.
    keywords: cases; covid-19; number; pakistan
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        item: #4477 of 7819
          id: cord-311086-i4e0rdxp
      author: Adekola, Hafeez Aderinsayo
       title: Mathematical modeling for infectious viral disease: The COVID‐19 perspective
        date: 2020-08-17
       words: 3283
      flesch: 31
     summary: key: cord-311086-i4e0rdxp authors: Adekola, Hafeez Aderinsayo; Adekunle, Ibrahim Ayoade; Egberongbe, Haneefat Olabimpe; Onitilo, Sefiu Adekunle; Abdullahi, Idris Nasir title: Mathematical modeling for infectious viral disease: The COVID‐19 perspective date: 2020-08-17 journal: J Public Aff DOI: 10.1002/pa.2306 sha: doc_id: 311086 cord_uid: i4e0rdxp In this study, we examined various forms of mathematical models that are relevant for the containment, risk analysis, and features of COVID‐19. Mathematical models address the need for understanding the transmission dynamics and other significant factors of the disease that would aid policymakers to make accurate decisions and reduce the rate of transmission of the disease.
    keywords: covid-19; disease; model; population; transmission
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        item: #4478 of 7819
          id: cord-311107-jvoyhv7y
      author: Genovese, Giovanni
       title: Varicella‐like exanthem associated with COVID‐19 in an 8‐year‐old girl: A diagnostic clue?
        date: 2020-05-19
       words: 217
      flesch: 36
     summary: The lesions were initially erythematous papules ( Figure 1A key: cord-311107-jvoyhv7y authors: Genovese, Giovanni; Colonna, Cristiana; Marzano, Angelo V. title: Varicella‐like exanthem associated with COVID‐19 in an 8‐year‐old girl: A diagnostic clue? date: 2020-05-19 journal: Pediatr Dermatol DOI: 10.1111/pde.14201 sha: doc_id: 311107 cord_uid: jvoyhv7y It has been reported that the novel coronavirus disease (COVID‐19) may be associated with a papulovesicular skin eruption predominantly involving the trunk.
    keywords: covid-19
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        item: #4479 of 7819
          id: cord-311125-v9ddes3c
      author: Cooper, Keiland W.
       title: COVID-19 and the chemical senses: supporting players take center stage
        date: 2020-07-01
       words: 9498
      flesch: 29
     summary: Four recently published studies -using species ranging from mouse to human -have explored the cell types in the OE that express ACE2 and other viral entry genes Chen et al., 2020b; Fodoulian et al., 2020; Ziegler et al., 2020) ; all four conclude that OSNs do not express ACE2 ( Figure 2 ). In contrast, vascular pericytes in the OB expressed high levels of ACE2 protein , consistent with the reported expression of Ace2 in perivascular cells in the brain and throughout the body (Chen et al., 2020a; He et al., 2020) .
    keywords: ace2; brain; cells; coronavirus; cov-2; covid-19; entry; epithelium; et al; expression; human; infection; mouse; nasal; neurons; olfactory; patients; protein; receptor; sars; sensory; smell; taste
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        item: #4480 of 7819
          id: cord-311129-5p9mf37g
      author: Yang, Dong
       title: COVID-19 & Chronic Renal Disease: Clinical characteristics & prognosis
        date: 2020-08-25
       words: 2816
      flesch: 35
     summary: The odds ratio of dialysis associated to mortality in CKD patients was 2.00 (95%CI 0.52-7.63), suggesting COVID-19 patients with dialysis-dependent CKD were at greater risk of in-hospital death. Strengths of our study include a cohort of CKD patients with COVID-19 from two study centers, and a detailed presentation focusing on clinical characters, course and outcomes of COVID-19 patients with underlying CKD who were not on dialysis.
    keywords: ckd; covid-19; dialysis; hospital; patients; rrt
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        item: #4481 of 7819
          id: cord-311155-8cvj4wdp
      author: Maideen, Naina Mohamed Pakkir
       title: Prophetic Medicine-Nigella Sativa (Black cumin seeds) – Potential herb for COVID-19?
        date: 2020-06-30
       words: 4182
      flesch: 32
     summary: A randomized controlled clinical trial of 50 obese volunteer women found that N. sativa oil significantly increased the levels of superoxide dismutase (SOD) which is important antioxidant enzyme acting against oxidative stress in the body [30] . [39] and a randomized, double blind, placebo-controlled clinical trial of 42 patients with rheumatoid arthritis (RA) where the participants of intervention group received 2 capsules of N. sativa oil 500mg, each day for 8 weeks and the levels of nitric oxide (NO) and malondialdehyde (MDA) decreased significantly in participants treated with N. sativa.
    keywords: activity; covid-19; n. sativa; nigella; oil; patients; placebo; sativa; trial
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        item: #4482 of 7819
          id: cord-311171-5n1aqrpa
      author: Ovejero, Santiago
       title: Coronovirus infection as a novel delusional topic
        date: 2020-05-08
       words: 671
      flesch: 40
     summary: Here, we present one early case of delusional contents related to COVID-19 infection. Timely research papers about COVID-19 in China Patients with mental health disorders in the COVID-19 epidemic World Health Organization., 2020.
    keywords: coronavirus; covid-19
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        item: #4483 of 7819
          id: cord-311195-oee19duz
      author: Gostic, Katelyn
       title: Estimated effectiveness of symptom and risk screening to prevent the spread of COVID-19
        date: 2020-02-24
       words: 8047
      flesch: 38
     summary: The middle and worst-case scenarios have predictable and discouraging consequences for the effectiveness of traveller screening, since they render large fractions of the population undetectable by fever screening ( Figure 2) . The arrival fever screen is the next greatest contributor, with its value arising from two factors: the potential to detect cases whose symptom onset occurred during travel, and the potential to catch cases missed due to imperfect instrument sensitivity in non-contact infrared thermal scanners used in traveller screening (Table 1) .
    keywords: cases; coronavirus; covid-19; epidemic; exposure; fraction; risk; screening; symptoms; travellers
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        item: #4484 of 7819
          id: cord-311201-y0lk9zet
      author: Serrano, Francisco
       title: The future of airport post COVID-19
        date: 2020-08-15
       words: 7088
      flesch: 42
     summary: Similar situation can be seen with airports operations as air traffic has reduced a lot due to the low demand for passenger booking and travel restrictions imposed by the countries. According to ALG Transport & Infrastructure published document (ALG Transport & Infrastructure, 2020), the governments should start as soon as possible a range of measures that will be required to ensure the sustainability of airport operations (see Figure 5 ).
    keywords: airlines; airport; aviation; business; cost; covid-19; crisis; demand; operations; passenger; service; situation; staff; term; time; traffic
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        item: #4485 of 7819
          id: cord-311207-qkkn0297
      author: Pegoraro, Manuela
       title: Evaluation of three immunochromatographic tests in COVID-19 serologic diagnosis and their clinical usefulness
        date: 2020-10-20
       words: 1667
      flesch: 39
     summary: Sensitivities were assessed on confirmed COVID-19 cases, combining IgG and IgM/IgA positive results, while specificities were estimated on the group of healthy volunteer's. Then, about half of blood samples from COVID-19 confirmed cases had been collected in the early stage, when antibodies are usually absent, thus partially impacting the diagnostic sensitivity.
    keywords: covid-19; igg; igm; sars; stage
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        item: #4486 of 7819
          id: cord-311215-x3b7ewo2
      author: Chao, Tiffany N.
       title: Tracheotomy in Ventilated Patients With COVID-19
        date: 2020-05-05
       words: 2046
      flesch: 45
     summary: 2. Tracheotomy before 21 days should not be routinely performed in COVID-19 patients solely for prolonged ventilator dependence, given the high risk of transmission and poor prognosis of patients requiring intubation and ventilation in the existing literature. Other indications for tracheotomy in COVID-19 patients should be considered on a caseby-case basis, such as patients with a known difficult airway.
    keywords: covid-19; days; patients; tracheotomy; ventilation
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        item: #4487 of 7819
          id: cord-311222-vw4b9xmg
      author: Haydar, Ali
       title: Palliative Care Utilization among Patients with COVID-19 in an Underserved Population: A Single-Center Retrospective Study
        date: 2020-05-23
       words: 2033
      flesch: 44
     summary: Palliative care and the COVID-19 pandemic Palliative care in humanitarian crisis: always something to offer Hospice utilization during the SARS outbreak in Taiwan The role and response of palliative care and hospice services in epidemics and pandemics: a rapid review to inform practice during the COVID-19 pandemic Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand Characteristics, symptom management and outcomes of 101 patients with COVID-19 referred for hospital palliative care Treatment of COVID-19: old tricks for new challenges COVID-19: decision making and palliative care Critical supply shortages-the need for ventilators and personal protective equipment during the Covid-19 pandemic National trends (2009-2013) for palliative care utilization for patients receiving prolonged mechanical ventilation A simplified screening tool to identify seriously ill patients in the Emergency Department for referral to a palliative care team Preliminary analysis of a modified screening tool to increase the frequency of palliative care consults It is important to assess the use of palliative care in response to the COVID-19 pandemic.
    keywords: care; covid-19; palliative; patients
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        item: #4488 of 7819
          id: cord-311284-5nxh7ybe
      author: Kumar, U.
       title: COVID-19 in rheumatic diseases: A random cross-sectional telephonic survey
        date: 2020-08-13
       words: 2204
      flesch: 48
     summary: Patients and methods: The present study was a cross-sectional, random telephonic survey conducted from 20 th April to 20 th July 2020 on patients with rheumatological All rights reserved. Patients with rheumatic diseases in India have similar incidence of COVID-19 infection compared to the community.
    keywords: covid-19; medrxiv; patients; preprint; review
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        item: #4489 of 7819
          id: cord-311316-j79nmq0j
      author: Tony, Abeer Abdelhady
       title: COVID-19-associated sleep disorders: A case report
        date: 2020-09-12
       words: 1460
      flesch: 42
     summary: The bidirectional relationship between sleep and immunity against infections Characteristics of lymphocyte subsets and cytokines in peripheral blood of 123 hospitalized patients with Sleep during naturally occurring respiratory infections: A pilot study Human immune system during sleep Restless legs syndrome -Theoretical roles The authors declare that they have no competing interests Funding Non declared. We reported one patient infected with acute respiratory syndrome coronavirus-2 (SARS-CoV-2) presented with sleep disorders; insomnia and restless leg syndrome.
    keywords: covid-19; disorders; patient; sleep; syndrome
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        item: #4490 of 7819
          id: cord-311327-50s8sja3
      author: Toh, Vi Vien
       title: Management of COVID-19 in burns patients: The experience of a UK burn centre
        date: 2020-07-03
       words: 143
      flesch: 8
     summary: key: cord-311327-50s8sja3 authors: Toh, Vi Vien; Antrum, John Henry George; Sloan, Brendan; Austin, Orla; Muthayya, Preetha title: Management of COVID-19 in burns patients: The experience of a UK burn centre date: 2020-07-03 journal: Burns DOI: 10.1016/j.burns.2020.06.026 sha: doc_id: 311327 cord_uid: 50s8sja3 nan We had two male patients who presented to the local Accident X-ray (Fig. 3) None. None. 1 5 1 Management 153 strategies for the burn ward during COVID-19 pandemic Managing chronic wounds during 155 novel coronavirus pneumonia outbreak European Centre for Disease Prevention and Control. Guidance 159 for discharge and ending isolation in the context of widespread 160 community transmission of COVID-19-first update Centre for Disease Prevention and Control Antibody 165 responses to SARS-CoV-2 in patients of novel coronavirus 166 disease 2019 Evaluating the 169 COVID-19 testing: the 174 threat of false-negative results
    keywords: covid-19
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        item: #4491 of 7819
          id: cord-311341-7ox30d2u
      author: Goenka, Anuj
       title: Implementation of Telehealth in Radiation Oncology: Rapid Integration During COVID-19 and its Future Role in our Practice
        date: 2020-10-09
       words: 4359
      flesch: 43
     summary: A HIPAA compliant platform, Amwell Telehealth (American Well Corporation, Boston MA), was selected to deliver telehealth care. Nevertheless, we continue to recommend two-way audio-video encounters as the standard of telehealth care to the extent possible, as J o u r n a l P r e -p r o o f we believe the video aspect of the visit is a very valuable component of being able to offer appropriate clinical advice and establish a patient-physician relationship.
    keywords: audio; care; patient; person; telehealth; video; visits
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        item: #4492 of 7819
          id: cord-311342-523zrpbl
      author: Shipe, Maren E.
       title: Modeling the Impact of Delaying the Diagnosis of Non-Small Cell Lung Cancer during COVID-19
        date: 2020-10-19
       words: 3549
      flesch: 43
     summary: To approximate the effect of COVID-19 on long-term survival after lung cancer resection, we utilized available data on the impact of significant complications after NSCLC resection on 5-year overall survival. Diagnosis and management of lung cancer? SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, China Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State Lessons Learned During the COVID-19 Virus Pandemic Risk Factors Associated With Acute Respiratory Distress Syndrome J o u r n a l P r e -p r o o f and Death in Patients With Coronavirus Disease Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy Estimates of the severity of coronavirus disease 2019 : a model-based analysis Report on the epidemiological features of coronavirus disease 2019 (covid-19) outbreak in the republic of korea from The Probability of Malignancy in Solitary Pulmonary Nodules STS database risk models: Predictors of mortality and major morbidity for lung cancer resection Can lung cancer screening by computed tomography be effective in areas with endemic histoplasmosis?
    keywords: cancer; covid-19; infection; lung; resection; stage; survival
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        item: #4493 of 7819
          id: cord-311353-ozqfsuh8
      author: Sun, Chun-Yang
       title: The role of Chinese medicine in COVID-19 pneumonia: A systematic review and meta-analysis
        date: 2020-07-08
       words: 1654
      flesch: 45
     summary: key: cord-311353-ozqfsuh8 authors: Sun, Chun-Yang; Sun, Ya-Lei; Li, Xin-Min title: The role of Chinese medicine in COVID-19 pneumonia: This meta-analysis was conducted to evaluate the clinical efficacy and safety of CM in the treatment of COVID-19 pneumonia.
    keywords: covid-19; pneumonia; rcts; treatment
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        item: #4494 of 7819
          id: cord-311376-mah8j8bj
      author: Liang, Xiaopeng
       title: Is COVID-19 more severe in older men?
        date: 2020-05-13
       words: 704
      flesch: 47
     summary: In a study of 1099 COVID-19 patients, the median age of patients with severe disease (173/1099) was 7 years higher than that of those with non-severe disease (926/1099). By analogy with SARS and MERS, lymphopenia and cytokine storm might play a role in the deterioration of COVID-19 patients.
    keywords: covid-19; patients; sars
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        item: #4495 of 7819
          id: cord-311401-7ugqjg5c
      author: Alser, O.
       title: Healthcare workers preparedness for COVID-19 pandemic in the occupied Palestinian territory: a cross-sectional survey
        date: 2020-05-13
       words: 2801
      flesch: 47
     summary: Compared to the West Bank, respondents from the Gaza Strip reported significantly greater lack of alcohol-based hand sanitizers (p=0.03) and gloves (p<0.001), but no meaningful differences were observed between regions on other PPE or infection control readiness (Table 3) . The primary outcomes was PPE provision and the secondary outcome was HCWs preparedness for the COVID-19 pandemic.
    keywords: covid-19; hcws; license; opt; ppe; preprint
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        item: #4496 of 7819
          id: cord-311413-uiwjrvru
      author: Chanda-Kapata, Pascalina
       title: COVID-19 and malaria: A symptom screening challenge for malaria endemic countries
        date: 2020-04-27
       words: 1736
      flesch: 39
     summary: Globally, all countries are at very high risk of COVID-19 while half of the world is at risk of malaria, with sub-Saharan countries bearing the blunt of malaria cases and deaths while South East Asia remain at high risk of both malaria and COVID-19 (WHO, 2020b,c). Since malaria tests are relatively more available (Landier et al., 2016) , we recommend that health workers perform rapid tests for malaria as they screen for COVID-19.
    keywords: countries; covid-19; health; malaria
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        item: #4497 of 7819
          id: cord-311431-5pi3bzli
      author: Korobelnik, Jean-François
       title: Response to letter: COVID-19 and macular edema—a necessary blindness?
        date: 2020-07-18
       words: 330
      flesch: 20
     summary: We believe that strategies for managing patients with retinal disease during this uncertain time should focus on the following: & Minimizing the risk of exposure to COVID-19 for both the patient and healthcare staff & Simplifying anti-vascular endothelial growth factor treatment regimens & Prioritizing treatment for those at greatest risk of irreversible vision loss By implementing stringent safety practices and triaging those who are most vulnerable, we have the opportunity to continue to provide the best possible care to patients. Guidance for anti-VEGF intravitreal injections during the COVID-19 pandemic Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations UMR 1219, F-33000 Graefe's Archive for Conflict of interest Jean-François Korobelnik is a consultant for Allergan, Bayer, Kanghong, Novartis, and Roche.
    keywords: covid-19; guidance
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        item: #4498 of 7819
          id: cord-311448-t17g47dj
      author: Brian, Zachary
       title: Oral Health and COVID-19: Increasing the Need for Prevention and Access
        date: 2020-08-13
       words: 3884
      flesch: 36
     summary: In this commentary, we explain why oral health care should be a public health priority in the response to the pandemic and discuss the aspects of dental care that make it challenging to accomplish this. Access to oral health care is especially limited for populations at high risk for COVID-19.
    keywords: access; care; covid-19; dental; disease; health; oral; pandemic; prevention
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        item: #4499 of 7819
          id: cord-311453-l6quzef6
      author: Klopfenstein, Timothée
       title: Impact of Tocilizumab on mortality and/or invasive mechanical ventilation requirement in a cohort of 206 COVID-19 patients
        date: 2020-08-13
       words: 2680
      flesch: 49
     summary: Patients in TCZ group seemed to be more severe than patients in ST group. The tocilizumab group (TCZ group) included all patients (except patients already in intensive care unit with IMV) whom received standard treatment and TCZ (8mg/kg per dose, 1 or 2 doses).
    keywords: covid-19; group; mortality; patients; tcz; treatment
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        item: #4500 of 7819
          id: cord-311477-gm0vg53l
      author: Doboszewska, Urszula
       title: Targeting zinc metalloenzymes in COVID‐19
        date: 2020-07-15
       words: 6201
      flesch: 39
     summary: Furthermore, we provide examples of compounds targeting zinc which have entered clinical trials in order to demonstrate that investigating zinc drugs may lead to success in the clinic. The examples of zinc ionophores are given in Table 1 .
    keywords: chloroquine; cov-2; covid-19; drug; et al; fingers; hydroxychloroquine; intracellular; ions; patients; proteins; sars; treatment; zinc
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        item: #4501 of 7819
          id: cord-311495-svgw59ic
      author: Ayati, Nayyereh
       title: Short and long term impacts of COVID-19 on the pharmaceutical sector
        date: 2020-07-03
       words: 3542
      flesch: 36
     summary: These regulation revisions include: & Fast-track approvals for COVID-19-related treatments; In Iran, this is in terms of Iran medicine list (IML) inclusion and registration process. Studies reported that induced demand in global pharmaceutical market, mainly due to panic buying of pharmaceuticals for chronic disorders, was estimated to be +8.9%, by March 2020
    keywords: covid-19; health; impacts; iran; market; medicines; pandemic; pharmaceutical; term; title
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        item: #4502 of 7819
          id: cord-311505-akcc9oms
      author: Geisen, Will R.
       title: Cytomegalovirus Enterocolitis secondary to experimental COVID-19 therapy
        date: 2020-09-22
       words: 1359
      flesch: 29
     summary: With immunomodulating therapies being used in experimental protocols and clinical trials for SARS-CoV-2 J o u r n a l P r e -p r o o f infection, colonoscopy is vital to diagnose gastrointestinal opportunistic infections that are associated with these treatment modalities Clinical Characteristics of Coronavirus Disease 2019 in China A Novel Coronavirus from Patients with Pneumonia in China Tocilizumab for the treatment of severe COVID-19 Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19 Clostridioides difficile in COVID-19 patients In vivo effects of the anti-interleukin-6 receptor inhibitor tocilizumab on the B cell compartment Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization Novel Coronavirus Infection: Gastrointestinal Manifestations Pooled Prevalence of Diarrhea among COVID-19 Toward an Algorithm for the Diagnosis and Management of CMV in Patients with Colitis The occurrence of diarrhea in COVID-19 patients Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology Excessive anxiety in IBD patients is unnecessary for COVID-19 Dear Editor-in-Chief,We are submitting the manuscript Cytomegalovirus Enterocolitis secondary to experimental COVID-19 therapy for consideration of publication as a Case Report. Additionally, studies have shown a significant alteration of gut microbiome and increased rates of C. difficile in COVID-19 patients, most presumably from immunomodulating therapies (6, 8) .
    keywords: covid-19; diarrhea; patients; therapies
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        item: #4503 of 7819
          id: cord-311523-erntrh3p
      author: Gisondi, P
       title: Dermatologists and SARS‐CoV‐2: The impact of the pandemic on daily practice
        date: 2020-04-22
       words: 2760
      flesch: 38
     summary: In the areas of Italy severely affected by the coronavirus outbreak, extra beds have been created in Internal Medicine wards for COVID-19 patients; dermatologists, along with doctors from other medical subspecialties, have therefore been asked to provide assistance to COVID-19 patients in these departments due to the shortage of doctors. Shortage of medical masks for health workers due to panic shopping from the population may jeopardize the safety of physicians dealing with COVID-19 patients.
    keywords: article; coronavirus; covid-19; infection; pandemic; patients; sars
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        item: #4504 of 7819
          id: cord-311535-ppkwd1kp
      author: Korakas, Emmanouil
       title: Obesity and COVID-19: immune and metabolic derangement as a possible link to adverse clinical outcomes
        date: 2020-07-01
       words: 2781
      flesch: 18
     summary: Obesity and heart failure: epidemiology, pathophysiology, clinical manifestations, and management Obesity cardiomyopathy: pathophysiology and evolution of the clinical syndrome Cellular mechanisms underlying obesityinduced arterial stiffness Oxidative stress and vascular disease in diabetes: is the dichotomization of insulin signaling still valid? Prolonged treatment with angiotensin 1-7 improves endothelial function in diet-induced obesity Mechanisms of thrombosis in obesity Takotsubo Cardiomyopathy Triggered by Influenza A Virus Severe Acute Respiratory Syndrome Coronavirus Viroporin 3a Activates the NLRP3 Inflammasome Obesity and type 2 diabetes mellitus drive immune dysfunction, infection development, and sepsis mortality Complex immune dysregulation in COVID-19 patients with severe respiratory failure Critical role for the NLRP3 inflammasome during acute lung injury Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes Clinical features of patients infected with 2019 novel coronavirus in Wuhan Differential effects of inhibition of interleukin 1 and 6 on myocardial, coronary and vascular function Complement receptor C5aR1 inhibition reduces pyroptosis in hDPP4-transgenic mice Infected with MERS-CoV Defective production of interleukin-1 beta in patients with type 2 diabetes mellitus: Restoration by proper glycemic control Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission Obesity induces a phenotypic switch in adipose tissue macrophage polarization Adipocytes properties and crosstalk with immune system in obesity-related inflammation Role of innate and adaptive immunity in obesity-associated metabolic disease HLH Across Speciality Collaboration, UK. key: cord-311535-ppkwd1kp authors: Korakas, Emmanouil; Ikonomidis, Ignatios; Kousathana, Foteini; Balampanis, Konstantinos; Kountouri, Aikaterini; Raptis, Athanasios; Palaiodimou, Lina; Kokkinos, Alexander; Lambadiari, Vaia title: Obesity and COVID-19: immune and metabolic derangement as a possible link to adverse clinical outcomes date: 2020-07-01 journal: Am J Physiol Endocrinol Metab DOI: 10.1152/ajpendo.00198.2020 sha: doc_id: 311535 cord_uid: ppkwd1kp Recent reports have shown a strong association between obesity and the severity of COVID-19 infection, even in the absence of other comorbidities.
    keywords: activation; acute; cells; covid-19; infection; obesity; patients; risk
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        item: #4505 of 7819
          id: cord-311544-7ihtyiox
      author: Sun, Tingzhe
       title: Modeling COVID-19 Epidemic in Heilongjiang Province, China
        date: 2020-05-29
       words: 2517
      flesch: 44
     summary: We estimated the influence of asymptomatic patients based on a data-driven model from Heilongjiang province. We trained our model based on COVID-19 epidemic in Heilongjiang province from January 23 to March 25, by which the last confirmed patient was cured in Heilongjiang province.
    keywords: asymptomatic; covid-19; model; patients; province
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        item: #4506 of 7819
          id: cord-311545-3rll9mca
      author: Bentley, Gillian R
       title: Don't blame the BAME: Ethnic and structural inequalities in susceptibilities to COVID‐19
        date: 2020-07-16
       words: 2807
      flesch: 30
     summary: Although East Asians appear to have higher expression of ACE2 levels compared to people of European descent, there does not seem to be any association between genetic variants and COVID-19 outcome (Cao et al., 2020) . These phenotypic traits also appear to be inter-generationally preserved (van Steijn et al., 2009 ) and, as mentioned above, are currently linked to risks for COVID-19 morbidity and mortality (Azkur et al., 2020) .
    keywords: bame; cov-2; covid-19; groups; health; individuals; sars; study
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        item: #4507 of 7819
          id: cord-311552-n16pdrc4
      author: Bäuerle, Alexander
       title: Psychological support in times of COVID-19: the Essen community-based CoPE concept
        date: 2020-04-20
       words: 739
      flesch: 43
     summary: We established a structured concept to support psychological burdened people in Essen, which is located in the Ruhr area, a metropolitan region with more than 5.1 million inhabitants in the heart of the federal state North Rhine Westphalia. We established a structured concept to support psychological burdened people in Essen, which is located in the Ruhr area, a metropolitan region with more than 5.1 million inhabitants in the heart of the federal state North Rhine Westphalia (NRW).
    keywords: community; covid-19; virus
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        item: #4508 of 7819
          id: cord-311559-vkb7a4cm
      author: Kanwugu, Osman N.
       title: HIV/SARS‐CoV‐2 coinfection: A global perspective
        date: 2020-07-28
       words: 2490
      flesch: 38
     summary: Global HIV & AIDS statistics -2020 fact sheet What does the COVID-19 pandemic mean for HIV, tuberculosis, and malaria control Challenges to HIV care and psychological health during the COVID-19 pandemic among people living with HIV in China COVID-19 pandemic disrupts HIV continuum of care and prevention: implications for research and practice concerning community-based organizations and frontline providers Disruption to HIV treatment in Africa during COVID-19 pandemic could double HIV deaths, modelling studies warn HIV services take a backseat to COVID-19 in Russia Living with HIV in the time of COVID-19: a glimpse of hope Public health, health systems and palliation planning for COVID-19 on an exponential timeline HIV care in times of the COVID-19 crisis-where are we now in Central and Eastern Europe? Lockdown fears for key populations A rapid assessment of the impact of the new coronavirus pneumonia epidemic on the health needs of HIV-infected patients HIV care in Central and Eastern Europe: How close are we to the target? Crisis for people living with HIV in Indonesia The burden of COVID-19 in people living with HIV: a syndemic perspective Potential impact of SARS-CoV-2 infection in HIV-positive patients in South Africa Strengthening health research capacity in sub-Saharan Africa: mapping the 2012-2017 landscape of externally funded international postgraduate training at institutions in the region Building research capacity in Africa: equity and global health collaborations Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Clinical features and outcomes of HIV patients with coronavirus disease 2019 Description of COVID-19 in HIV-infected individuals: a single-centre SARS-CoV-2 co-infected patients in Istanbul, Turkey Hospitalized patients with COVID-19 and HIV: a case series Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China Clinical characteristics of 145 patients with corona virus disease 2019 (COVID-19 Epidemiologic and clinical characteristics of 26 cases of COVID-19 arising from patient-to-patient transmission in Liaocheng, China Clinical course of 2019 novel coronavirus disease (COVID-19) in individuals present during the outbreak on the Diamond Princess cruise ship COVID-19 in patients with HIV: clinical case series Clinical characteristics and outcomes in people living with HIV hospitalized for COVID-19 Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis Mortality analyses 4 Cases: HIV and SARS-CoV-2 co-infection in patients from Long Island Clinical features and outcome of HIV/ SARS-CoV-2 co-infected patients in the Bronx SARS-CoV-2: recent reports on antiviral therapies based on lopinavir/ritonavir, darunavir/ umifenovir, hydroxychloroquine, remdesivir, favipiravir and other drugs for the treatment of the new coronavirus Could HIV infection alter the clinical course of SARS-CoV-2 infection? In addition, there have been reports that several HIV/ AIDS prevention and control centers globally have been converted to COVID-19 treatment centers, which denies HIV patients of their ART.
    keywords: case; cov-2; covid-19; hiv; infection; patients; sars
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        item: #4509 of 7819
          id: cord-311579-4jhoatkw
      author: Bhatt, Harshil
       title: Venous thromboembolism and COVID-19: a case report and review of the literature
        date: 2020-10-15
       words: 1765
      flesch: 42
     summary: A novel coronavirus from patients with pneumonia in China Anticoagulation in COVID-19 Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV, and lessons from the past Incidence of venous thromboembolism in hospitalized patients with COVID-19 Humanitas COVID-19 Task Force. The breakdown of these clots leads to elevation of D-dimer levels and fibrin degradation product levels, both of which are associated with poor prognosis in COVID-19 patients, including the need for intensive care unit (ICU) admission, and even death
    keywords: anticoagulation; coronavirus; covid-19; patient; pulmonary
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        item: #4510 of 7819
          id: cord-311580-dzlh5obt
      author: Snapiri, Ori
       title: Delayed diagnosis of paediatric appendicitis during the COVID‐19 pandemic
        date: 2020-06-08
       words: 2485
      flesch: 41
     summary: Moreover, we found that appendicitis complication rate in the COVID-19 period in Israel was roughly twice as high as complication rate during the same period in the previous year. Upon arrival, he was taken to the area assigned for COVID-19 suspected patients' despite the fact he was not suffering from any typical symptom.
    keywords: abdominal; appendicitis; covid-19; patient; symptoms
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        item: #4511 of 7819
          id: cord-311588-ocz2rzy7
      author: Gilligan, Jeffrey
       title: Collateral Damage During the COVID-19 Pandemic
        date: 2020-05-14
       words: 478
      flesch: 52
     summary: What remains unknown is how many patients with known or unknown pathologies are having progression of a deficit (i.e. worsening vision secondary to a supersellar mass or worsening cervical myelopathy) that would otherwise have brought them to seek urgent medical care. The support network, that is often the catalyst to seek medical care, and also the system that provides for them in times of convalescence, must be reestablished.
    keywords: care; patients
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        item: #4512 of 7819
          id: cord-311620-zs2mpeke
      author: Handa, Rahul
       title: Covid-19-associated acute haemorrhagic leukoencephalomyelitis
        date: 2020-09-02
       words: 1486
      flesch: 44
     summary: Our case report supports the hypotheses of association between CNS manifestation and severe form of Covid-19 infection with raised inflammatory markers. Patients with chronic kidney disease who develop Covid-19 infection have increased risk of severity and mortality as compared with general population [9] .
    keywords: ahl; covid-19; patient
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        item: #4513 of 7819
          id: cord-311633-i9ret7bw
      author: Péré, Hélène
       title: Unexpected diagnosis of COVID-19-associated disorders by SARS-CoV-2-specific serology
        date: 2020-08-04
       words: 1683
      flesch: 42
     summary: Abbott SARS-CoV-2 IgG assay sensitivity. Thus, the frequency of SARS-CoV-2-specific IgG was around 10-fold higher in COVID-19 areas than COVID-19 free areas (75% versus 8%; P < 0.001).
    keywords: cov-2; covid-19; igg; sars
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        item: #4514 of 7819
          id: cord-311635-hf6vrbyx
      author: Reuken, Philipp Alexander
       title: Between Fear and Courage: Attitudes, Beliefs, and Behavior of Liver Transplantation Recipients and Waiting List Candidates during the COVID‐19 Pandemic
        date: 2020-06-08
       words: 3485
      flesch: 41
     summary: The Lancet Liver injury in COVID-19: management and challenges COVID-19 in long-term liver transplant patients: preliminary experience from an Italian transplant centre in Lombardy Determining risk factors for mortality in liver transplant patients with COVID-19 Coronaviruses and Immunosuppressed Patients: The Facts During the Third Epidemic Care of patients with liver disease during the COVID-19 pandemic: EASL-ESCMID position paper Highlights for management of patients with Autoimmune Liver Disease during COVID-19 pandemia COVID-19 pandemic will have a long-lasting impact on the quality of cirrhosis care Using social and behavioural science to support COVID-19 pandemic response. All rights reserved A Novel Coronavirus from Patients with Pneumonia in China WHO Director-General's opening remarks at the media briefing on COVID-19 -11 Johns Hopkins Coronavirus Resource Center COVID-19 and the policy sciences: initial reactions and perspectives Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.
    keywords: covid-19; fear; liver; patients; recipients; transplant; transplantation
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        item: #4515 of 7819
          id: cord-311636-8l7jlvvj
      author: Oikonomou, Evangelos
       title: Hospital attendance and admission trends for cardiac diseases during the COVID-19 outbreak and lockdown in Greece
        date: 2020-08-18
       words: 941
      flesch: 32
     summary: Results A falling trend of cardiology ED visits and hospital admissions starting from the week that the restrictive measures due to COVID-19 were implemented was observed. key: cord-311636-8l7jlvvj authors: Oikonomou, Evangelos; Aznaouridis, Konstantinos; Barbetseas, John; Charalambous, Georgios; Gastouniotis, Ioannis; Fotopoulos, Vasileios; Gkini, Konstantia-Paraskevi; Katsivas, Apostolos; Koudounis, Georgios; Koudounis, Panagiotis; Koutouzis, Michael; Lamprinos, Dimitrios; Lazaris, Evangelos; Lazaris, Efstathios; Lazaros, George; Marinos, George; Platogiannis, Nikolaos; Platogiannis, Dimitrios; Siasos, Gerasimos; Terentes-Printzios, Dimitrios; Theodoropoulou, Alexandra; Theofilis, Panagiotis; Toutouzas, Konstantinos; Tsalamandris, Sotiris; Tsiafoutis, Ioannis; Vavouranakis, Manolis; Vogiatzi, Georgia; Zografos, Theodoros; Baka, Eleni; Tousoulis, Dimitris; Vlachopoulos, Charalambos title: Hospital attendance and admission trends for cardiac diseases during the COVID-19 outbreak and lockdown in Greece date: 2020-08-18 journal: Public Health DOI: 10.1016/j.puhe.2020.08.007 sha: doc_id: 311636 cord_uid: 8l7jlvvj Abstract Objectives The COVID-19 outbreak, along with implementation of lockdown and strict public movement restrictions, in Greece have affected hospital visits and admissions.
    keywords: covid-19; outbreak; period; visits
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        item: #4516 of 7819
          id: cord-311651-v2ff33jd
      author: Long, Nathaniel
       title: Contributions of Health Professions Students to Health System Needs During the COVID-19 Pandemic: Potential Strategies and Process for U.S. Medical Schools
        date: 2020-07-15
       words: 4425
      flesch: 37
     summary: Six weeks into the program (mid-to late April), the total number of students on task forces or awaiting placement = 418; students onboarded to functioning task forces = 348 (medical students = 323, public health students = 13, nurse practitioner students = 8, physician assistant students = 4). As a result, faculty often consider teaching medical students in the first few years of their curriculum as extra work, added time, and decreased efficiency.
    keywords: care; covid-19; education; health; medical; needs; pandemic; students; system
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        item: #4517 of 7819
          id: cord-311669-112kxj5s
      author: Imdad, Kashif
       title: A district-level susceptibility and vulnerability assessment of the COVID-19 pandemic's footprint in India
        date: 2020-11-08
       words: 9110
      flesch: 38
     summary: Ironically, most of the highly urbanized and economically well-off states seem to have reported higher COVID-19 susceptibility, since the initial epicentres of the virus outbreak were in their large cities. Therefore, when this study was commenced in April, 2020, the district-wise numbers of COVID-19 cases were collected on four dates from the MoHFW, GoI, database to understand the patterns of the virus' spread in each timeslot and feasibly represent each of the lockdown phases.
    keywords: analysis; areas; cases; country; covid-19; covid-19 cases; districts; et al; health; india; lockdown; numbers; outbreak; spread; susceptibility; virus
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        item: #4518 of 7819
          id: cord-311673-z4hkw17g
      author: Uzzan, Mathieu
       title: Why is SARS-CoV-2 infection more severe in obese men? The gut lymphatics - lung axis hypothesis
        date: 2020-06-23
       words: 2975
      flesch: 32
     summary: Higher risk of death was further reported for males with cardiovascular comorbidities within COVID-19 ICU patients [3, 4] . Further investigations demonstrated that peripheral inflammatory monocytes and T cells through their production of GM-CSF may incite cytokine storm in severe COVID-19 patients [15, 16] .
    keywords: cells; covid-19; fat; inflammation; patients; sars; syndrome
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        item: #4519 of 7819
          id: cord-311679-m6poosn3
      author: Santos, Glenn-Milo
       title: Economic, Mental Health, HIV Prevention and HIV Treatment Impacts of COVID-19 and the COVID-19 Response on a Global Sample of Cisgender Gay Men and Other Men Who Have Sex with Men
        date: 2020-07-11
       words: 5588
      flesch: 39
     summary: We characterized the economic, mental health, HIV prevention and HIV treatment impacts of COVID-19 and the COVID-19 response, and examined whether sub-groups of our study population are disproportionately impacted by COVID-19. New data on from the U.S. has not only reinforced this point but also underscored the ongoing need for uninterrupted access to HIV prevention tools gay men and other MSM may need [13] .
    keywords: access; covid-19; gay; health; hiv; men; msm; prevention; sex
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        item: #4520 of 7819
          id: cord-311682-npi03i7q
      author: Malicki, J
       title: Impact of COVID-19 on the performance of a radiation oncology department at a major comprehensive cancer centre in Poland during the first ten weeks of the epidemic
        date: 2020-08-16
       words: 3221
      flesch: 46
     summary: Every week thereafter, we reviewed the case mix and status of treated patients based on radiotherapy accepting new patients who met newly elaborated national and international radiotherapy and COVID-19 guidelines. Due to the risk of widespread contagion and the restrictions imposed by the state of epidemic, treatment for medical conditions unrelated to COVID-19 has been severely affected, including radiotherapy for cancer patients.
    keywords: cancer; covid-19; measures; number; patients; precautionary; radiotherapy; staff
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        item: #4521 of 7819
          id: cord-311694-2b2swi0l
      author: Grima, Simon
       title: A Country Pandemic Risk Exposure Measurement Model
        date: 2020-10-09
       words: 5796
      flesch: 41
     summary: Some studies 8 suggest such factor variables as Population Density measured by the number of persons per square kilometre, Night-time Light Intensity measured by the night light development index. Although there are various studies that have indicated factor variables that are important for addressing and measuring the vulnerability of countries, the COVID-19 pandemic has indicated a serious need to go back to the drawing board.
    keywords: analysis; country; covid-19; economic; exposure; factor; health; level; model; pandemic; risk; variables; vulnerability
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        item: #4522 of 7819
          id: cord-311730-189vax2m
      author: Becker, Richard C.
       title: Covid-19 treatment update: follow the scientific evidence
        date: 2020-04-27
       words: 4518
      flesch: 34
     summary: The number of clinical trials in Covid-19 patients, either planned or ongoing is increasing on a daily basis. [3] ( On March 28, 2020 the United States Food and Drug Administration (FDA issued) an emergency use authorization (EUA) permitting chloroquine phosphate (medical grade) and hydroxychloroquine sulfate to be added to the strategic national stockpile (SNS) (Fig. 2) .
    keywords: chloroquine; covid-19; disease; drug; effects; health; hydroxychloroquine; patients; potential; qtc; research; sars; treatment
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        item: #4523 of 7819
          id: cord-311749-yp313biv
      author: Chalmers, James D.
       title: Rewiring the Immune Response in COVID-19
        date: 2020-09-15
       words: 1947
      flesch: 32
     summary: There are, however, important differences in the inflammatory profile of HLH and severe COVID-19, suggesting a distinct pathophysiology. Taken together, severe COVID-19 appears to involve a delicate and dynamic balance between excess inflammation and deficient antiinflammatory and antiviral defenses.
    keywords: covid-19; emphysema; mortality; paraseptal; patients; response
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        item: #4524 of 7819
          id: cord-311752-stqrf50k
      author: Akbariqomi, Mostafa
       title: Clinical characteristics and outcome of hospitalized COVID-19 patients with diabetes: A single-center, retrospective study in Iran
        date: 2020-09-24
       words: 2629
      flesch: 38
     summary: A single center study World Health Organization Hospitalization rates and characteristics of patients hospitalized with laboratory-confirmed coronavirus disease 2019-COVID-NET, 14 States Communicating the risk of death from novel coronavirus disease (COVID-19) Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Clinical management of severe acute respiratory infection when novel coronavirus ( 2019-nCoV) infection is suspected: interim guidance Acute Respiratory Distress Syndrome: The Berlin Definition Sex difference and smoking predisposition in patients with COVID-19 ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 Current smoking, former smoking, and adverse outcome among hospitalized COVID-19 patients: a systematic review and meta-analysis Comorbidity and its impact on 1590 patients with Covid-19 in China: A Nationwide Analysis Clinical characteristics and risk factors for mortality of COVID-19 patients with diabetes in Wuhan, China: a two-center, retrospective study Clinical characteristics and outcomes of patients with severe covid-19 with diabetes Clinical characteristics and outcomes of patients with diabetes and COVID-19 in association with glucose-lowering medication Diabetes is a risk factor for the progression and prognosis of COVID-19 The alteration of Th1/Th2/Th17/Treg paradigm in patients with type 2 diabetes mellitus: relationship with diabetic nephropathy Cells of innate and adaptive immunity in type 2 diabetes and obesity COVID-19 and diabetes: Knowledge in progress Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission COVID-19 patients with hypertension have more severe disease: a multicenter retrospective observational study A: chest CT of a 29-year-old male patient without diabetes; B: chest CT from a 49-year-old male patient with diabetes %) Diabetes status of COVID-19 patients and frequent monitoring of glycemia would be helpful to prevent deteriorating clinical conditions.
    keywords: characteristics; covid-19; diabetes; disease; patients; study
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        item: #4525 of 7819
          id: cord-311758-wof4yi39
      author: Clauw, Daniel J.
       title: Considering the potential for an increase in chronic pain after the COVID-19 pandemic
        date: 2020-06-03
       words: 3187
      flesch: 35
     summary: Aydin Atar E. The impact of perceived social support on anxiety, depression and severity of pain and burnout among Turkish females with fibromyalgia Postinfectious irritable bowel syndrome-a meta-analysis Altered pituitaryadrenal axis responses to provocative challenge tests in adult survivors of childhood abuse Post-infective and chronic fatigue syndromes precipitated by viral and non-viral pathogens: prospective cohort study Posttraumatic stress disorder in convalescent severe acute respiratory syndrome patients: a 4-year follow-up study Severe acute respiratory syndrome (SARS): epidemiology and clinical features Long-term outcome and quality of life of patients treated in surgical intensive care: a comparison between sepsis and trauma Opioid-induced immunosuppression and carcinogenesis promotion theories create the newest trend in acute and chronic pain pharmacotherapy Stress and psychological distress among SARS survivors 1 year after the outbreak EULAR revised recommendations for the management of fibromyalgia Long-term psychiatric morbidities among SARS survivors Was SARS a mental health catastrophe? Hypothalamic-pituitary-adrenal stress axis function and the relationship with chronic widespread pain and its antecedents Epidemiology of chronic musculoskeletal pain Predicting chronic symptoms after an acute stressor-lessons learned from 3 medical conditions Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome Induction of neurasthenic musculoskeletal pain syndrome by selective sleep stage deprivation Clinical findings and pain symptoms as potential risk factors for chronic TMD: descriptive data and empirically identified domains from the OPPERA case-control study Major life events and minor stressors: identifying mediational links in the stress process COVID-19 and mental health: a review of the existing literature A community-based survey of fibromyalgia-like pain complaints following the World Trade Center terrorist attacks Why stress is bad for your brain Health-related quality of life and posttraumatic stress disorder in survivors of the acute respiratory distress syndrome Considerations for post-acute rehabilitation for survivors of COVID-19: JMIR public health and surveillance Biopsychosocial model of irritable bowel syndrome The Centre for Evidence-Based Medicine. In this unprecedented crisis, the immediate healthcare concerns are directed towards containment and acute patient care.
    keywords: chronic; covid-19; health; pain; patients; symptoms; syndrome
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        item: #4526 of 7819
          id: cord-311816-j8c2lk7y
      author: D’Elia, Emilia
       title: Coronavirus Disease 2019: Where are we and Where are we Going? Intersections Between Coronavirus Disease 2019 and the Heart
        date: 2020-06-29
       words: 1703
      flesch: 35
     summary: This has imposed a significant burden on our hospital in terms of healthcare personnel, dedicated spaces (including intensive care areas) and time spent by clinicians, who are committed to assisting COVID-19 patients. In all this, the fact that comorbidities play a key role in the clinical evolution of COVID-19 patients and affect prognosis has been demonstrated and deserves attention.
    keywords: cardiac; coronavirus; covid-19; disease; patients
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        item: #4527 of 7819
          id: cord-311819-iy8r1iml
      author: Peretti-Watel, Patrick
       title: Anxiety, depression and sleep problems: a second wave of COVID-19
        date: 2020-09-22
       words: 2030
      flesch: 39
     summary: Our cross-sectional survey cannot allow us to conclude that the COVID-19 lockdown was a direct cause of the occurrence of mental health symptoms, nor does it establish trends during the lockdown in the prevalence of major depression and anxiety disorders, according to the DSM-V. However, our results strongly supported the hypothesis that this lockdown has had a massive impact on the mental health of the French population. On the contrary, working outside the home full-time was associated with fewer mental health problems (depressive symptoms, anxiety or sleep problems) than staying at home (even for teleworking, except for anxiety).
    keywords: anxiety; covid-19; health; lockdown; sleep
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        item: #4528 of 7819
          id: cord-311838-ymn96yj4
      author: LIU)刘茜玮(, Qianwei
       title: Analysis of the Influence of the Psychology Changes of Fear Induced by the COVID-19 Epidemic on the Body
        date: 2020-07-15
       words: 4204
      flesch: 38
     summary: key: cord-311838-ymn96yj4 authors: LIU)刘茜玮(, Qianwei; ZHAO)赵国桢(, Guozhen; JI)嵇波(, Bo; LIU)刘翼天(, Yitian; ZHANG)张靖宇(, Jingyu; MOU)牟秋杰(, Qiujie; SHI)石天宇(, Tianyu title: Analysis of the Influence of the Psychology Changes of Fear Induced by the COVID-19 Epidemic on the Body date: 2020-07-15 journal: World J Acupunct Moxibustion DOI: 10.1016/j.wjam.2020.06.007 sha: doc_id: 311838 cord_uid: ymn96yj4 In this paper, the theory of Fear injury kidney in traditional Chinese medicine is systematically reviewed, and it is found that long-term or excessive psychological changes of fear are likely to damage kidney qi and kidney essence. A new measure designed to assess anticipatory dementia in older adults Design and validation of a new instrument to assess fear of falling in Parkinson's disease Emotional distress impacts fear of the future among breast cancer survivors not the reverse Self-efficacy for labor and childbirth fears in nulliparous pregnant women Validity and time course of surgical fear as measured with with the Surgical Fear Questionnaire in patients undergoing cataract surgery Fear of progression in patients with cancer, diabetes mellitus and chronic arthritis Comparison of self-report and behavioral proceduresfor assessing acrophobia Fear of flying assessment: A contribution to the Italian validation of two self-report measures A fear schedule for use in behavior therapy Exploring the relationship between fear of positive evaluation and social anxiety Measuring co-presence and social presence in virtual environments-psychometric construction of a German scale for a fear of public speaking scenario Annual Review of Cybertherapy and Telemedicine The measurement of fear of crime The Fear of COVID-19 Scale: Development and Initial Validation 58 patients with phobia were mainly treated with acupuncture
    keywords: anxiety; covid-19; deficiency; epidemic; essence; fear; kidney; patients; psychological
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        item: #4529 of 7819
          id: cord-311847-2czqs84q
      author: Pennisi, Manuela
       title: SARS-CoV-2 and the Nervous System: From Clinical Features to Molecular Mechanisms
        date: 2020-07-31
       words: 9018
      flesch: 36
     summary: The differences in the sequence of spike proteins between SARS-CoV and SARS-CoV-2 will enable scientists to identify epitopes in COVID-19 patients for the development of monoclonal antibodies against this virus. COVID-19: Consider cytokine storm syndromes and immunosuppression Analysis of clinical characteristics and laboratory findings of 95 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A retrospective analysis The interface between stroke and infectious disease: Infectious diseases leading to stroke and infections complicating stroke The clinical pathology of severe acute respiratory syndrome (SARS): A report from Progression in migraine: Role of mast cells and pro-inflammatory and anti-inflammatory cytokines The pathogenesis and treatment of the 'Cytokine Storm' in COVID-19 Analysis of the clinical effect of olfactory training on olfactory dysfunction after upper respiratory tract infection Anosmia in COVID-19: A Bumpy Road to Establishing a Cellular Mechanism Massive transient damage of the olfactory epithelium associated with infection of sustentacular cells by SARS-CoV-2 in golden Syrian hamsters Olfactory transmucosal SARS-CoV-2 invasion as port of Central Nervous System entry in COVID-19 patients A Mouse Model of SARS-CoV-2 Infection and Pathogenesis Prevalence of Chemosensory Dysfunction in COVID-19 Patients: A Systematic Review and Meta-analysis Reveals Significant Ethnic Differences Smell and taste dysfunction in patients with SARS-CoV-2 infection: A review of epidemiology, pathogenesis, prognosis, and treatment options.
    keywords: ace2; acute; brain; cells; cns; coronavirus; cov-2; covid-19; covs; disease; human; infection; olfactory; patients; sars; study; syndrome; viral
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        item: #4530 of 7819
          id: cord-311848-8n9ee57a
      author: Giesen, Nicola
       title: Evidence-based Management of COVID-19 in Cancer Patients – Guideline by the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO)
        date: 2020-09-21
       words: 7686
      flesch: 37
     summary: 57-60 If caring for COVID-19 patients, we strongly recommend that 185 HCWs wear FFP2/N95 respirators (AII t ) and personal protective equipment including gloves, gowns 186 and eye protection such as goggles or face shields (AII r ). 11 Given that many targeted agents adversely affect immune 303 function we marginally support discontinuation of targeted therapy in COVID-19 patients (CIII).
    keywords: aii; cancer; cohort; coronavirus; cov-2; covid-19; disease; infection; patients; risk; sars; study; therapy; treatment
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        item: #4531 of 7819
          id: cord-311853-k6efd9vg
      author: Lim, Rachel HF
       title: Decline in pneumococcal disease incidence in the time of COVID-19 in Singapore
        date: 2020-08-15
       words: 1256
      flesch: 37
     summary: key: cord-311853-k6efd9vg authors: Lim, Rachel HF; Chow, Angela; Ho, Hanley J title: Decline in pneumococcal disease incidence in the time of COVID-19 in Singapore date: 2020-08-15 journal: J Infect DOI: 10.1016/j.jinf.2020.08.020 sha: doc_id: 311853 cord_uid: k6efd9vg nan Chow et al reported a marked decline in influenza incidence in Singapore during the first four months of 2020, likely attributable to public health measures aimed at controlling the coronavirus disease 2019 (COVID-19) pandemic (1) . In conclusion, we observed a decreased incidence of pneumococcal disease at our institution that corresponded with the time period when public health measures were implemented to control COVID-19, suggesting that these measures had also had an inadvertent effect on the transmission of S. pneumoniae.
    keywords: covid-19; disease; measures
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        item: #4532 of 7819
          id: cord-311871-13n4st4q
      author: Blaivas, Michael
       title: Unexpected finding of myocardial depression in 2 healthy young patients with COVID‐19 pneumonia: possible support for COVID‐19‐related myocarditis
        date: 2020-06-13
       words: 1015
      flesch: 40
     summary: He denied any contact with COVID-19 patients or exposures. These cases serve to raise the awareness of emergency physicians and others treating COVID-19 patients to consider evaluating the heart with POCUS, not just for pericardial effusion but also for left ventricular systolic function on a more routine basis.
    keywords: covid-19; lung; patients; ultrasound
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        item: #4533 of 7819
          id: cord-311872-09jzyyin
      author: Effenberger, Maria
       title: Systemic inflammation as fuel for acute liver injury in COVID-19
        date: 2020-08-10
       words: 2973
      flesch: 45
     summary: Of all hospitalized COVID-19 patients, 41 (42%) showed elevated aspartate aminotransferase (AST) concentration. COVID-19 patients with elevated AST exhibited significantly higher IL-6 (p< 0.001), ferritin (p< 0.001), LDH (p< 0.001) and CRP (p < 0.05) serum concentrations compared to patients with normal AST.
    keywords: ast; covid-19; fig; icu; il-6; injury; liver; p<0.001; patients
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        item: #4534 of 7819
          id: cord-311889-fntwg3g8
      author: Alizadehsani, R.
       title: Risk Factors Prediction, Clinical Outcomes, and Mortality of COVID-19 Patients
        date: 2020-07-09
       words: 5401
      flesch: 54
     summary: 13.8-19 .1% reported COVID-19 patients in Wuhan, China became ailments critically. [14] investigated five patients of large-vessel stroke who were diagnosed with COVID-19 in a New York City hospital with a 5% prevalence of stroke among COVID-19 patients.
    keywords: covid-19; disease; et al; features; mortality; patients; preprint; risk; study; symptoms
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        item: #4535 of 7819
          id: cord-311926-n7co0jtu
      author: Donà, Daniele
       title: COVID-19 Pandemic: Perspective of an Italian Tertiary Care Pediatric Center
        date: 2020-09-01
       words: 3186
      flesch: 46
     summary: Predicting a rapid spread of the SARS-CoV-2 virus within our region, in the afternoon of February 24th the Chief Executive Officer (CEO) of Padua University Hospital called for an emergency meeting with all the department chairmen and the mandates received were: • to ensure the protection of the healthcare workers, as the top priority; • to rigorously implement all the conventional rules emanated by the WHO for preventing the infection • to minimize the risk of admitting into hospital asymptomatic COVID-19 positive patients; • to adapt/transform some hospital areas in order to be able to admit and treat suspected/confirmed; COVID-19 pediatric patients Predicting a rapid spread of the SARS-CoV-2 virus within our region, in the afternoon of February 24th the Chief Executive Officer (CEO) of Padua University Hospital called for an emergency meeting with all the department chairmen and the mandates received were: • to ensure the protection of the healthcare workers, as the top priority; • to rigorously implement all the conventional rules emanated by the WHO for preventing the infection • to minimize the risk of admitting into hospital asymptomatic COVID-19 positive patients; • to adapt/transform some hospital areas in order to be able to admit and treat suspected/confirmed; COVID-19 pediatric patients • To ensure continuity of treatment when appropriate and needed. On a daily basis, the head nurses were required to call in the families who were scheduled to be admitted to the hospital, within the 1-2 days prior to the admission to run a telephone pre-triage, based on a standardized questionnaire aiming to pick-up epidemiologic risk factors or signs and symptoms of COVID-19 infection in the patient or in his/her accompanying family member.
    keywords: children; covid-19; healthcare; hospital; patients; sars
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        item: #4536 of 7819
          id: cord-311942-oju4gosw
      author: Grewal, Parneet
       title: Acute Ischemic Stroke and COVID-19: Experience From a Comprehensive Stroke Center in Midwest US
        date: 2020-08-20
       words: 2746
      flesch: 42
     summary: Systemic thrombotic complications occurred in 3 (23%) COVID-19 AIS patients. To validate our findings, to further identify mechanisms of stroke and outcome variables, we compared our cohort with stroke patients from the same time frame in 2020 along with historical cohort from 2019.
    keywords: ais; covid-19; data; group; patients; stroke
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        item: #4537 of 7819
          id: cord-311965-3x3tjzhi
      author: Alexander, Jan
       title: Early Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19
        date: 2020-08-07
       words: 5169
      flesch: 31
     summary: The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality Editorial: Low population mortality from COVID-19 in countries south of latitude 35 degrees North supports vitamin D as a factor determining severity Prior diagnoses and medications as risk factors for COVID-19 in a Los Angeles Health System Low serum 25-hydroxyvitamin D (25[OH]D) levels in patients hospitalised with COVID-19 are associated with greater disease severity Factors Associated with Hospitalization and Disease Severity in a Racially and Ethnically Diverse Population of COVID-19 Patients Vitamin D and respiratory health Vitamin D deficiency as a risk factor for infection, sepsis and mortality in the critically ill: Systematic review and meta-analysis Link between community-acquired pneumonia and vitamin D levels in older patients Addition of vitamin D status to prognostic scores improves the prediction of outcome in community-acquired pneumonia Vitamin D Status and Long-Term Mortality in Community-Acquired Pneumonia: Secondary Data Analysis from a Prospective Cohort Association between prehospital vitamin D status and incident acute respiratory failure in critically ill patients: A retrospective cohort study Vitamin D increases the antiviral activity of bronchial epithelial cells in vitro Vitamin D represses rhinovirus replication in cystic fibrosis cells by inducing LL-37 Effects of vitamin D on airway epithelial cell morphology and rhinovirus replication Vitamin D decreases respiratory syncytial virus induction of NF-kappaB-linked chemokines and cytokines in airway epithelium while maintaining the antiviral state Relationship to Duration of Infection Vitamin D inhibition of pro-fibrotic effects of transforming growth factor beta1 in lung fibroblasts and epithelial cells The role of vitamin D supplementation in the risk of developing pneumonia: Epidemiological studies suggested an inverse association between circulating levels of 25(OH)-D3, a biomarker of vitamin D status, and inflammatory biomarkers, including CRP and IL-6
    keywords: covid-19; deficiency; infections; patients; sars; selenium; status; supplementation; treatment; vitamin; zinc
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        item: #4538 of 7819
          id: cord-311970-o9xao5rl
      author: Ayerbe, Luis
       title: The association between treatment with heparin and survival in patients with Covid-19
        date: 2020-05-31
       words: 1858
      flesch: 46
     summary: However, the use of heparin in Covid-19 patients is still supported by limited evidence. While the nature of the hypoperfusion of lungs in Covid-19 patients is still not fully understood, our findings support that there is a thrombotic component in the development of respiratory distress for these patients
    keywords: covid-19; heparin; mortality; patients
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        item: #4539 of 7819
          id: cord-312002-4qhvljpv
      author: Pacheco-Barrios, Kevin
       title: COVID-19 pandemic and Farr’s law: A global comparison and prediction of outbreak acceleration and deceleration rates
        date: 2020-09-17
       words: 5436
      flesch: 50
     summary: Finally, we performed a post-hoc extraction of the new cases for June 10, 2020 (one point extraction), and the political actions against COVID-19 per country, from the University of Washington Health Index and Evaluation C: Both ratios are equal to 1; D: First ratio less than 1�0 but Second ratio higher than 1�0; E: both ratios are less than 1�0� � No cases for more than 10 days�� Data belong to June 09, on June 10 there was no cases reported�� The countries with end date beyond June 10 are countries having more than zero predicted cases or deaths after we ended our simulation (June 10, 2020), meaning they could continue with the pandemic wave beyond the end our simulation. The predominant region for both ratios was Europe, while high income countries were predominant for the R 1 and middle-income for R 2 ( Table 2 ).
    keywords: cases; countries; covid-19; data; deaths; epidemic; health; june; new
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        item: #4540 of 7819
          id: cord-312029-xsojdbdk
      author: Sham, Lauren
       title: The COVID-19 pandemic and Community Health Workers: An opportunity to maintain delivery of care and education for families of children with epilepsy in Zambia
        date: 2020-10-02
       words: 1430
      flesch: 39
     summary: As requirements for physical distancing have led to restrictions on the availability of health care services, many countries have adapted methods of telemedicine to sustain care access for patients [1] , while making difficult decisions surrounding which aspects of direct clinical care can be deferred and the time span acceptable for delaying chronic medical care Beyond our original goals, this program has provided a unique model of health care access for a chronic medical condition during times of infectious disease outbreaks requiring physical distancing, which is feasible to implement in a developing region where telehealth mechanisms are limited.
    keywords: care; epilepsy; health; program
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        item: #4541 of 7819
          id: cord-312036-5867bc6i
      author: Decker, Annegrit
       title: Prolonged SARS‐CoV‐2 shedding and mild course of COVID‐19 in a patient after recent heart transplantation
        date: 2020-06-09
       words: 1944
      flesch: 43
     summary: 2, 3 Since many patients with COVID-19 develop cardiovascular complications 4 , heart transplant recipients may be at particular risk. Our experiences in this case underscore the particularities in management of COVID-19 in heart transplant recipients.
    keywords: covid-19; heart; immunosuppression; recipients; transplant; transplantation
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        item: #4542 of 7819
          id: cord-312038-g76cpjp7
      author: Brunaugh, Ashlee D.
       title: Broad-Spectrum, Patient-Adaptable Inhaled Niclosamide-Lysozyme Particles are Efficacious Against Coronaviruses in Lethal Murine Infection Models
        date: 2020-10-07
       words: 11069
      flesch: 39
     summary: Though hLYS is surface active, it appeared to only slightly enhance the dissolution of NIC compared to NIC particles blended with lactose (F). We have previously demonstrated that hen egg white lysozyme is robust to processinduced aggregation using typical particle engineering techniques (51) , which provided part of the rationale for its selection as a therapeutically active carrier for the aerosol delivery of NIC particles.
    keywords: activity; cells; cov-2; covid-19; delivery; dose; drug; fig; formulation; hlys; infection; lung; mers; mice; nic; niclosamide; particles; powder; sars; spray; study; treatment
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        item: #4543 of 7819
          id: cord-312057-4zfaqkxm
      author: Leppla, Idris E.
       title: Optimizing Medication Treatment of Opioid Use Disorder During COVID-19 (SARS-CoV-2)
        date: 2020-05-14
       words: 1667
      flesch: 45
     summary: Another advantage of a video conferencing modality that can accommodate multiple participants (ie, Zoom) is that patients may participate in group sessions with other patients for collective accountability and sharing of experiences. Critical conversations between clinicians and patients, as well as cost-benefit for continued treatment to individual patients is crucial.
    keywords: buprenorphine; methadone; opioid; patients; treatment
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        item: #4544 of 7819
          id: cord-312094-czuw4t7i
      author: Radic, Aleksandar
       title: Fear and Trembling of Cruise Ship Employees: Psychological Effects of the COVID-19 Pandemic
        date: 2020-09-16
       words: 8883
      flesch: 51
     summary: As uncertainty crawls in every pore of cruise ships, causing waves of stress, depression, anxiety, and panic, cruise ship employees are in need to create a common sense from what appears to be a hopeless situation. This research aimed to gain a deeper understanding of the psychological effects of the COVID-19 pandemic on cruise ship employees stuck at sea.
    keywords: anxiety; companies; covid-19; covid-19 pandemic; crew; cruise; cruise ship; employees; line; members; pandemic; sea; ship; ship employees
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        item: #4545 of 7819
          id: cord-312114-lcyv211y
      author: Graichen, Heiko
       title: The role of an Orthopaedic Surgeon in the time of Covid-19 Pandemic–a German perspective
        date: 2020-05-13
       words: 2618
      flesch: 54
     summary: Wards from the Orthopaedic department are reorganised as quarantine wards for Covid-19 patients. It is located in Bavaria, the state in Germany with the highest number of Covid-19 patients of all German states.
    keywords: covid-19; number; orthopaedic; pandemic; patients; time
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        item: #4546 of 7819
          id: cord-312125-j9l6l3dx
      author: Pau, Alice K.
       title: Convalescent Plasma for the Treatment of COVID-19: Perspectives of the National Institutes of Health COVID-19 Treatment Guidelines Panel
        date: 2020-09-25
       words: 1800
      flesch: 42
     summary: Given the lack of data from properly powered RCTs, and the need to inform regulatory decision making regarding continued access to convalescent plasma, both the FDA and the Mayo Clinic performed retrospective, indirect evaluations of efficacy by using EAP data, hypothesizing that patients who received plasma units with higher titers of neutralizing antibodies would have better clinical outcomes. Ann Intern Med DOI: 10.7326/m20-6448 sha: doc_id: 312125 cord_uid: j9l6l3dx In the United States, the efficacy and safety of convalescent plasma for treating coronavirus disease 2019 (COVID-19) is currently being tested in randomized placebo-controlled clinical trials.
    keywords: convalescent; covid-19; patients; plasma; treatment
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        item: #4547 of 7819
          id: cord-312137-u260m04t
      author: Morrison, Daniel R.
       title: Head and neck oncologic surgery in the COVID‐19 pandemic: Our experience in a deep south tertiary care center
        date: 2020-05-19
       words: 3376
      flesch: 46
     summary: We feel that an early and cohesive strategy to triaging surgical cases, PPE usage, and minimizing exposure of personnel is essential to providing care for HNS patients during this pandemic. Of note, we feel strongly that a team-based approach toward completing surgical cases is of the utmost importance in this situation.
    keywords: care; cases; covid-19; head; neck; pandemic; patients; surgery; time
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        item: #4548 of 7819
          id: cord-312172-bkygtdeo
      author: Malhotra, Atul
       title: ACE2, Metformin, and COVID-19
        date: 2020-07-31
       words: 2121
      flesch: 29
     summary: We hypothesize that patients with COVID-19 taking metformin will have higher circulating ACE2 levels and lower morbidity and mortality compared with matched controls. These data would allow an assessment of the effect of metformin on circulating ACE2 levels, as well as the ability of circulating ACE2 levels to predict morbidity and mortality due to COVID-19.
    keywords: ace2; covid-19; metformin; patients; sars
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        item: #4549 of 7819
          id: cord-312178-tojgojjf
      author: Segars, James
       title: Prior and Novel Coronaviruses, COVID-19, and Human Reproduction: What Is Known?
        date: 2020-04-16
       words: 5366
      flesch: 41
     summary: An in silico analysis Structure, Function, and Evolution of Coronavirus Spike Proteins Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptorbinding site in spike protein domain A Structural insights into coronavirus entry Human and bovine coronaviruses recognize sialic acid-containing receptors similar to those of influenza C viruses Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Ezrin interacts with the SARS coronavirus Spike protein and restrains infection at the entry stage Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2 Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways In a 2005 study of eight postmortem SARS-CoV patients, testicular tissue contained focal atrophy despite lacking identifiable SARS viral RNA (24) .
    keywords: case; coronavirus; cov-2; covid-19; disease; infection; patients; pregnancy; reports; sars; transmission; women
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        item: #4550 of 7819
          id: cord-312183-zkoj5d8c
      author: Frydman, Galit H.
       title: Coagulation Status and Venous Thromboembolism Risk in African Americans: A Potential Risk Factor in COVID-19
        date: 2020-07-24
       words: 4486
      flesch: 25
     summary: A report of thromboelastography findings and other parameters of hemostasis COVID19: consider cytokine storm syndromes and immunosuppression Cross talk pathways between coagulation and inflammation COVID-19 and African Americans Racial differences in venous thromboembolism SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa Influenza and SARScoronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts Clinical course and risk factors for mortality of adult patients with COVID-19 in Wuhan, China: a retrospective cohort study COVID-19 and the cardiovascular system ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 The impact of COPD and smoking history on the severity of Covid-19: a systematic review and meta-analysis Immune mechanisms of pulmonary intravascular coagulopathy in COVID-19 pneumonia Endothelial cell infection and endotheliitis in COVID-19 Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases Thrombosis and vascular inflammation in diabetes: mechanisms and potential therapeutic targets Coagulation takes center stage in inflammation Contact pathway of coagulation and inflammation New insights into the role of adipose tissue in thrombosis Coagulation and inflammation in long-term cancer survivors: results from the adult population Cancer-associated thrombosis: an overview of mechanisms, risk factors, and treatment Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans Placental pathology in COVID-19 positive mothers: preliminary findings Placental pathology in COVID-19 Venous thrombosis among critically ill patients with coronavirus disease 2019 (COVID-19) Acute pulmonary embolism in COVID-19 patients on CT angiography and relationship to D-dimer levels Pulmonary embolism in COVID-19 patients: awareness of an increased prevalence Thrombosis risk associated with COVID-19 infection. key: cord-312183-zkoj5d8c authors: Frydman, Galit H.; Boyer, Edward W.; Nazarian, Rosalynn M.; Van Cott, Elizabeth M.; Piazza, Gregory title: Coagulation Status and Venous Thromboembolism Risk in African Americans: A Potential Risk Factor in COVID-19 date: 2020-07-24 journal: Clin Appl
    keywords: african; americans; coagulation; covid-19; differences; disease; patients; risk; studies; thromboembolism; thrombosis
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        item: #4551 of 7819
          id: cord-312185-ojdrzskl
      author: Zhao, Dahai
       title: Evidence-Based Framework and Implementation of China’s Strategy in Combating COVID-19
        date: 2020-10-07
       words: 4563
      flesch: 51
     summary: The results of this study are reinforced by a more recent study of Wuhan COVID-19 cases, which argues that elevated body temperature is not a general presentation. Considering that the actual implementation and control of COVID-19, including the screening, isolation, and treatment of the noted cases, takes place in and is under the auspices of that particular prefecture-level in the whole country, the paper will focus on a single prefecture-level city wherein the rate of COVID-19 cases seemed beyond control based on understood norms.
    keywords: cases; china; covid-19; isolation; patients; screening; taizhou
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        item: #4552 of 7819
          id: cord-312192-hxhohtmj
      author: Zhu, Lan
       title: Coronavirus Disease 2019 Pneumonia in Immunosuppressed Renal Transplant Recipients: A Summary of 10 Confirmed Cases in Wuhan, China
        date: 2020-04-18
       words: 3426
      flesch: 44
     summary: Serving as control patients without immunosuppression, the 10 family members with confirmed COVID-19 pneumonia had a mean age of 42.3 AE 14.4 yr, which was similar to that of the infected transplant recipients (45.0 AE 14.0 yr, p > 0.05). To evaluate the clinical features and outcomes of COVID-19 pneumonia in kidney transplant recipients.
    keywords: chen; covid-19; disease; patients; pneumonia; recipients; transplant
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        item: #4553 of 7819
          id: cord-312194-1jiaghrb
      author: Brondani, M.
       title: The HIV and SARS-CoV-2 Parallel in Dentistry from the Perspectives of the Oral Health Care Team
        date: 2020-09-18
       words: 4770
      flesch: 45
     summary: Future studies should include oral health care providers across Canada, as well as the patients receiving oral health care during this pandemic. M. Brondani, contributed to conception, design, data acquisition, analysis, and interpretation, drafted and critically revised the manuscript; L. Donnelly, contributed to data analysis and interpretation, critically revised the manuscript. Future studies should include other providers across Canada, as well the patients receiving oral health care during this pandemic.
    keywords: aids; care; covid-19; dental; health; hiv; pandemic; participants
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        item: #4554 of 7819
          id: cord-312205-j8szwaqj
      author: Giuntoli, Michele
       title: Lessons learnt from COVID 19: An Italian multicentric epidemiological study of orthopaedic and trauma services
        date: 2020-05-28
       words: 3536
      flesch: 54
     summary: We report just one case of death among COVID patients. The number of COVID patients evaluated and treated was reported for each centre.
    keywords: aid; covid; covid-19; march; orthopaedic; patients
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        item: #4555 of 7819
          id: cord-312218-qtxh4ttp
      author: Chakraborty, Jayajit
       title: Social Inequities in the Distribution of COVID-19: An Intra-Categorical Analysis of People with Disabilities in the U.S.
        date: 2020-09-18
       words: 2191
      flesch: 32
     summary: The objective is to determine whether COVID-19 incidence is significantly greater in counties containing higher percentages of socio-demographically disadvantaged PwDs, based on race, ethnicity, poverty status, age, and biological sex. The specific objective is to determine whether COVID-19 incidence is significantly greater in counties containing higher percentages of socio-demographically disadvantaged PwDs, based on their race, ethnicity, poverty status, age, and biological sex.
    keywords: counties; covid-19; disability; incidence; pwds
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        item: #4556 of 7819
          id: cord-312251-t6omrr07
      author: Vancheri, Sergio Giuseppe
       title: Radiographic findings in 240 patients with COVID-19 pneumonia: time-dependence after the onset of symptoms
        date: 2020-05-30
       words: 3509
      flesch: 44
     summary: The most frequent lesions in COVID-19 patients were GGO (intermediate/late phase) and reticular alteration (early phase) while consolidation gradually increased over time. During the subsequent outbreak in the Western world, chest X-ray (CXR), together with arterial blood gas analysis and clinical presentation, in patients positive to RT-PCR, was recommended as a useful and easily available tool to support the initial diagnosis and for the subsequent management of COVID-19 patients [7, 8] .
    keywords: chest; covid-19; cxr; findings; group; onset; patients
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        item: #4557 of 7819
          id: cord-312252-4l3ok44o
      author: Elbeddini, Ali
       title: Barriers to conducting deprescribing in the elderly population amid the COVID-19 pandemic
        date: 2020-05-29
       words: 2878
      flesch: 32
     summary: Virtual care is the future of healthcare and in order to retain the benefits of deprescribing, additional initiatives should be in place to address the challenges that elderly patients may experience in accessing deprescribing virtually. These initiatives should involve teaching elderly patients how to use technology to access health services and with technical support in place to address any concerns.
    keywords: deprescribing; health; healthcare; lack; medications; patients
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        item: #4558 of 7819
          id: cord-312278-rin733w4
      author: Wang, Yung‐Chih
       title: Current diagnostic tools for coronaviruses–From laboratory diagnosis to POC diagnosis for COVID‐19
        date: 2020-08-13
       words: 2256
      flesch: 41
     summary: Bat coronaviruses in China SARS and MERS: recent insights into emerging coronaviruses From SARS to MERS, thrusting coronaviruses into the spotlight Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia A novel coronavirus from patients with pneumonia in China Technical Advisory Group for Infectious H. COVID-19: what is next for public health? Clinical features of patients infected with 2019 novel coronavirus in Wuhan Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region Detection of SARS coronavirus in patients with severe acute respiratory syndrome by conventional and real-time quantitative reverse transcription-PCR assays Laboratory diagnosis of emerging human coronavirus infections-the state of the art Detection of SARS-CoV-2 in different types of clinical specimens The role of laboratory diagnostics in emerging viral infections: the example of the Middle East respiratory syndrome epidemic Serologic and molecular biologic methods for SARS-associated coronavirus infection Serology of severe acute respiratory syndrome: implications for surveillance and outcome Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus Coronavirus COVID-19 outbreak: Latest news, information and updates COVID-19) Emergency Use Authorizations for Medical Devices Genome composition and divergence of the novel coronavirus (2019-nCoV) originating in China Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation A pneumonia outbreak associated with a new coronavirus of probable bat origin Primer design for quantitative real-time PCR for the emerging coronavirus SARS-CoV-2 The laboratory diagnosis of COVID-19 infection: current issues and challenges Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Negative nasopharyngeal and Oropharyngeal swab does not rule out COVID-19 Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes Saliva as a non-invasive specimen for detection of SARS-CoV-2 Saliva is a reliable tool to detect SARS-CoV-2 The Applied Biosystems TaqPath COVID-19 Combo Kit Neutralizing antibodies against SARS-CoV-2 and other human coronaviruses The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application Chembio Announces Launch of DPP COVID-19 Serological Point-of-Care Test BD Veritor™ System for Rapid Detection of SARS-CoV-2 Development of a colloidal gold-based immunochromatographic strip for rapid detection of Klebsiella pneumoniae serotypes K1 and K2 Development of immunochromatographic colloidal gold test strip for rapid detection of Haemophilus influenzae in clinical specimens Feasibility of using colloidal gold immunochromatography for point-of-care identification of parathyroid glands during thyroidectomy The COVID-19 IgG/IgM Rapid Test Accula SARS-CoV-2 Test VitaPCR™ COVID-19 Assay Vivalytic Rapid Test for COVID-19 COVID-19 Test (At-Home Kit Laboratory TaqPath SARS-CoV-2 Assay Fulgent Coronavirus Disease (COVID-19) RT-PCR test Everlywell COVID-19 Test Home Collection Kit Quest Self-collection Kit for COVID-19 Gravity Diagnostics COVID-19 Assay KPMAS COVID-19 Test Kroger Health COVID-19
    keywords: coronavirus; cov-2; covid-19; detection; diagnosis; disease; sars; test
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        item: #4559 of 7819
          id: cord-312293-2h37qxcg
      author: Kennelly, Brendan
       title: The COVID-19 pandemic in Ireland: An overview of the health service and economic policy response
        date: 2020-09-09
       words: 5828
      flesch: 55
     summary: Ireland's land border with Northern Ireland is another area which deserves close attention during this health emergency. There are also significant differences in death rates between Ireland and Northern Ireland and between Ireland and the UK mainland 37 .
    keywords: cases; covid-19; government; health; healthcare; ireland; pandemic; people; public; system; virus
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        item: #4560 of 7819
          id: cord-312305-ll29frwc
      author: Sun, Shihui
       title: Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2
        date: 2020-11-11
       words: 4757
      flesch: 44
     summary: Additionally, immunostaining of lung sections showed a significant infiltration of CD68 + macrophages and Ly-6G + neutrophils in MASCp36 infected mice ( fig. Aged mice challenged with high dose of MASCp36 developed typical respiratory symptoms and exhibited features like ruffled fur, hunched back, and reduced activity.
    keywords: binding; complex; cov-2; covid-19; disease; fig; lung; mace2; mascp36; mice; model; mouse; rbdmascp36; sars
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        item: #4561 of 7819
          id: cord-312313-guphuppy
      author: Patel, Zara M
       title: Letter: Precautions for Endoscopic Transnasal Skull Base Surgery During the COVID-19 Pandemic
        date: 2020-04-15
       words: 1578
      flesch: 44
     summary: 3 Healthcare providers are at high risk of infection when taking care of COVID-19 patients without PPE. When endonasal surgery cannot be postponed in a COVID-19 positive patient, based on guidelines now being used in China, we have recommended to our institutional officials that we utilize full powered air purifying respirator (an enclosed powered system with high efficiency particulate air filter), acknowledging that they have challenging decisions surrounding allocation of limited resources that are urgently needed by our critical care teams taking care COVID-19 patients.
    keywords: colleagues; covid-19; otolaryngology; patients; surgery
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        item: #4562 of 7819
          id: cord-312340-hpuoren5
      author: Holstein, Sarah A.
       title: Oncology Treatment in the Era of COVID‐19: We Cannot Afford to Hit the Pause Button
        date: 2020-06-02
       words: 1967
      flesch: 34
     summary: The Role of Clinical Trial Participation in Cancer Research: Barriers, Evidence, and Strategies Early Impact of COVID-19 on the Conduct of Oncology Clinical Trials and Long-Term Opportunities for Transformation: Findings From an Adapting to a pandemic -conducting oncology trials during the SARS-CoV-2 pandemic Time to activate lung cancer clinical trials and patient enrollment: a representative comparison study between two academic centers across the atlantic Invisible barriers to clinical trials: the impact of structural, infrastructural, and procedural barriers to opening oncology clinical trials Effect of the COVID-19 pandemic on cancer treatment and research The many faces of the anti-COVID immune response Accepted Article It should also be noted that some institutions have opened COVID-19 clinical trials in remarkably short time periods (i.e., in a matter of weeks), which raises the question as to why most oncology trials take 3-8 months to open at academic centers (7, 8) .
    keywords: cancer; covid-19; oncology; patients; trials
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        item: #4563 of 7819
          id: cord-312356-95yyi0jb
      author: Hernández-Huerta, Daniel
       title: The impact of COVID-19 on Acute Psychiatric Inpatient Unit
        date: 2020-05-19
       words: 567
      flesch: 29
     summary: Moreover, mental health staff often has inadequate training on the management of respiratory infectious diseases, which adds to some features of patients with pre-existing mental health conditions, such as inadequate insight or psychomotor excitement, being unable to practice infection control measures, as well as limited awareness regarding the risk of infection, that may contribute to the transmission of COVID-19. Similar difficulties have been described in delivering electroconvulsive therapy because of the shortage of personal protective equipments for healthcare staff who cannot perform such essential therapy in safe conditions (Tor et al., 2020) .
    keywords: covid-19; health
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        item: #4564 of 7819
          id: cord-312360-ynemtqua
      author: Zhao, Ruxing
       title: Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals
        date: 2020-09-29
       words: 5055
      flesch: 43
     summary: Conflictingly, T2D patients had a lower median level of Th cell count, but less patients in the T2D group had decreased Th cell proportion compared to those in the NDM group. Although the T2D group had a lower median level of Th cell count, they had a lower incidence of decreased Th cell count at the same time (see Table 3 ).
    keywords: cell; count; covid-19; diabetes; group; patients; t2d
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        item: #4565 of 7819
          id: cord-312362-i18rlo2r
      author: Yan, Linlin
       title: The relationship between perceived stress and emotional distress during the COVID-19 outbreak: Effects of boredom proneness and coping style
        date: 2020-10-29
       words: 3821
      flesch: 34
     summary: The results showed that higher perceived stress was associated with more emotional distress including depression, fear, compulsion-anxiety, neurasthenia, and hypochondria. key: cord-312362-i18rlo2r authors: Yan, Linlin; Gan, Yiqun; Ding, Xu; Wu, Jianhui; Duan, Hongxia title: The relationship between perceived stress and emotional distress during the COVID-19 outbreak: Effects of boredom proneness and coping style date: 2020-10-29 journal: J Anxiety Disord DOI: 10.1016/j.janxdis.2020.102328 sha: doc_id: 312362 cord_uid: i18rlo2r
    keywords: anxiety; boredom; coping; covid-19; depression; distress; pandemic; proneness; stress
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        item: #4566 of 7819
          id: cord-312366-8qg1fn8f
      author: Adiga, Aniruddha
       title: Mathematical Models for COVID-19 Pandemic: A Comparative Analysis
        date: 2020-10-30
       words: 8804
      flesch: 45
     summary: Since the surveillance systems have relatively stabilized in recent weeks, the development of forecasting models has gained traction and several models are available in the literature. The mobility network is derived by combining commuter and airline networks, to model time spent per day by individuals of region (patch)
    keywords: covid-19; data; disease; epidemic; forecasting; forecasts; health; individual; interventions; mobility; models; number; pandemic; population; spread; time
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        item: #4567 of 7819
          id: cord-312374-gu9tq48n
      author: Martin Arranz, Eduardo
       title: Management of COVID-19 Pandemic in Spanish Inflammatory Bowel Disease Units: Results From a National Survey
        date: 2020-06-04
       words: 2490
      flesch: 43
     summary: Thirteen doctors (24%) attend patients in monographic IBD clinics, and the rest of the surveyed doctors (5, 9.3%) usually attend IBD patients but only in general consultation (Fig. 2 ). Regarding the management of IBD patients contacting their physicians with mild symptoms suggesting COVID-19, 92.6% of surveyed IBD units referred patients to their primary care physician or the emergency department; of these, 28% (14 sites) referred all immunosuppressed patients to the emergency department and 10% (5 sites) referred all IBD patients regardless of their current treatment.
    keywords: covid-19; disease; ibd; pandemic; patients; units
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        item: #4568 of 7819
          id: cord-312388-pc89ybxw
      author: Singhania, Namrata
       title: Current Overview on Hypercoagulability in COVID-19
        date: 2020-08-04
       words: 4218
      flesch: 38
     summary: That study also compared patients with COVID-19-associated acute respiratory distress syndrome (ARDS) with a matched cohort of non-COVID-19 ARDS patients and found the rate of PE was higher in COVID-19 patients [11.7% vs. 2.1%; odds ratio (OR) 6.2, 95% CI 1.6-23.4; p < 0.008]. Clinical characteristics of coronavirus disease 2019 in China An atypical presentation of novel coronavirus disease 2019 (COVID-19) COVID-19 and coagulopathy: frequently asked questions Endothelial cell infection and endotheliitis in COVID-19 Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19 The factor VIII acute phase response requires the participation of NFκB and C/EBP Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans Post-mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction Hypercoagulability of COVID-19 patients in Intensive Care Unit.
    keywords: acute; anticoagulation; covid-19; dimer; dose; icu; levels; patients; vte
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        item: #4569 of 7819
          id: cord-312398-teu3tdbq
      author: Pocard, Marc
       title: A special edition of the Journal of Visceral Surgery on Covid-19: what problems, dangers and solutions have been identified?
        date: 2020-05-04
       words: 648
      flesch: 48
     summary: So, how will cancer surgery go forward? Thus, if in France tomorrow, a Regional Health Agency (ARS) should require a surgical team to move to a Covid-19-negative center in order to perform cancer surgery, should this be seen as an element of progress and finally an organization that transcends the divides between public and private medicine?
    keywords: covid-19
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        item: #4570 of 7819
          id: cord-312399-7oaerpee
      author: Park, Joo-Hyun
       title: The Clinical Manifestations and Chest Computed Tomography Findings of Coronavirus Disease 2019 (COVID-19) Patients in China: A Proportion Meta-Analysis
        date: 2020-05-01
       words: 4658
      flesch: 45
     summary: However, some COVID-19 patients demonstrate no symptoms or complain of only gastrointestinal (GI) symptoms; furthermore, the clinical features of COVID-19 patients diagnosed outside of Wuhan, China differed from those of patients diagnosed in Wuhan [18] . The objectives of this study were to identify the clinical features and chest CT findings of COVID-19 patients and to compare the characteristics of patients diagnosed in Wuhan and in other areas by integrating the findings reported in previous studies.
    keywords: analysis; coronavirus; covid-19; disease; patients; studies; study; wuhan
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        item: #4571 of 7819
          id: cord-312434-yx24golq
      author: Deng, Ziqin
       title: Bibliometric and Visualization Analysis of Human Coronaviruses: Prospects and Implications for COVID-19 Research
        date: 2020-09-23
       words: 6227
      flesch: 40
     summary: Leading researchers from various fields of human coronavirus research are listed to facilitate collaboration and promote effective disease prevention and control. This is partially due to the unclear knowledge map of human coronavirus research and an inadequate understanding of the present research status, hotspots and development trends.
    keywords: analysis; coronavirus; cov; covid-19; human; mers; outbreak; publications; research; sars
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        item: #4572 of 7819
          id: cord-312467-kbhljong
      author: Boilève, Alice
       title: COVID-19 management in a cancer center: the ICU storm
        date: 2020-07-31
       words: 4119
      flesch: 44
     summary: In this regard, some cancer centers have their own ICU (dedicated to cancer patients only) that would receive COVID-19 patients in the context of pandemic. They received a time-limited training resulting in a 2-day observation course with their ICU colleagues before caring ICU patients.
    keywords: beds; cancer; care; covid-19; hospital; icu; pandemic; patients; workers
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        item: #4573 of 7819
          id: cord-312477-2y88gzji
      author: Mlcochova, P.
       title: Combined point of care nucleic acid and antibody testing for SARS-CoV-2: a prospective cohort study in suspected moderate to severe COVID-19 disease.
        date: 2020-06-18
       words: 4922
      flesch: 46
     summary: Rapid combined tests have the potential to transform our management of COVID-19, including inflammatory manifestations where nucleic acid test results are negative. Rapid combined tests have the potential to transform our management of COVID-19, including inflammatory manifestations where nucleic acid test results are negative.
    keywords: acid; antibody; cov-2; covid-19; igg; license; medrxiv; preprint; sars; test
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        item: #4574 of 7819
          id: cord-312484-epbhdx55
      author: Wang, Hongliang
       title: COVID-19 infection epidemic: the medical management strategies in Heilongjiang Province, China
        date: 2020-03-18
       words: 983
      flesch: 43
     summary: They also supervised the procedures of medical staffs in the isolation wards by wireless communication equipment. Medical staffs in Heilongjiang province were divided into 4 groups (Fig. 1 ).
    keywords: covid-19; patients; staffs
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        item: #4575 of 7819
          id: cord-312486-rumqopg0
      author: Jacob, Chaim Oscar
       title: On the genetics and immunopathogenesis of COVID-19
        date: 2020-09-10
       words: 11535
      flesch: 38
     summary: -1 beta in macrophages Influence of glutamine on cytokine production by human gut in vitro Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts A whole-genome association study of major determinants for host control of HIV-1 IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes LY6E impairs coronavirus fusion and confers immune control of viral disease Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus SARS-CoV-2 ORF3b is a potent interferon antagonist whose activity is further increased by a naturally occurring elongation variant Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients Imbalanced host response to SARS-CoV-2 drives development of COVID-19 Severe acute respiratory syndrome coronavirus viroporin 3a activates the NLRP3 inflammasome Virus-host interactome and proteomic survey of PBMCs from COVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis Immunology of COVID-19: current state of the science Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study Temporal relationship of viral load, ribavirin, interleukin (IL)-6, IL-8, and clinical progression in patients with severe acute respiratory syndrome Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Host and environmental factors influencing individual human cytokine responses COVID-19: consider cytokine storm syndromes and immunosuppression A single-cell atlas of the peripheral immune response in patients with severe COVID-19 Inhibition of natural killer cell cytotoxicity by interleukin-6: implications for the pathogenesis of macrophage activation syndrome Neutrophil-to-lymphocyte ratio predicts critical illness patients with 2019 coronavirus disease in the early stage Dysregulation of immune response in patients with COVID-19 in Wuhan, China Heightened innate immune responses in the respiratory tract of COVID-19 patients Clinical features of patients infected with 2019 novel coronavirus in Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice Complement evasion strategies of viruses: an overview The Complement System in COVID-19: Friend and Foe? Complement activation contributes to severe acute respiratory syndrome coronavirus pathogenesis Highly pathogenic coronavirus N protein aggravates lung injury by MASP-2-mediated complement over-activation. Functional exhaustion of antiviral lymphocytes in COVID-19 patients Clinical and immunological features of severe and moderate coronavirus disease 2019 Complex immune dysregulation in COVID-19 patients with severe respiratory failure Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent Coronaviruses and immunosuppressed patients: the facts during the third epidemic Uneventful course in patients with inflammatory bowel disease during the severe acute respiratory syndrome coronavirus 2 Outbreak in Northern Italy Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19 The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) directly decimates human spleens and lymph nodes Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implication Longitudinal analyses reveal immunological misfiring in severe COVID-19 Mouse model of SARS-CoV-2 reveals inflammatory role of type I Interferon signaling Persistence of memory in times of COVID-19 Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls No one is naïve: the significance of heterologous T-cell immunity Heterologous immunity between viruses Heterologous T cell immunity in severe hepatitis C virus infection Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing Neutralizing Antibody Responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications Convergent antibody responses to SARS-CoV-2 in convalescent individuals Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019 SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses Viral kinetics and antibody responses in patients with COVID-19.
    keywords: ace2; activation; cells; children; complement; coronavirus; cov-2; covid-19; cytokine; disease; expression; host; human; infection; patients; response; risk; sars; syndrome; system; virus
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        item: #4576 of 7819
          id: cord-312499-gd2wgti3
      author: Neville, Mariana Fontes Lima
       title: The paradox of COVID-19 and pediatric anesthesiology: opinion of the Pediatric Anesthesia Committee of the Brazilian Society of Anesthesiology
        date: 2020-05-13
       words: 1183
      flesch: 35
     summary: First, given that pre-school children have six to eight upper airway infections a year [5] caused by rhinovirus, influenza, syncytial respiratory virus, among others and, second, that children infected by SARS-CoV-2 will have mild and non-specific clinical presentations, it is impossible to clinically distinguish COVID-19 from other frequent respiratory infections in the young pediatric population. One of the known precepts of pediatric anesthesia is to manage the airway from less to more invasive approach, in that facial mask ventilation is routinely practiced.
    keywords: anesthesia; children; covid-19; pediatric
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        item: #4577 of 7819
          id: cord-312518-510gmyb4
      author: Bersanelli, Melissa
       title: Controversies about COVID-19 and anticancer treatment with immune checkpoint inhibitors
        date: 2020-03-26
       words: 2462
      flesch: 28
     summary: questions for impact assessment Coronavirus COVID-19 global cases by the center for systems science and engineering The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Risk of COVID-19 for cancer patients Presumed asymptomatic carrier transmission of COVID-19 From targeting the tumor to targeting the immune system: transversal challenges in oncology with the inhibition of the PD-1/PD-L1 axis The INVIDIa study Immunological insights on influenza infection and vaccination during immune checkpoint blockade in cancer patients Associazione Italiana di Oncologia Medica) Clinical characteristics and treatment of immune-related adverse events of immune checkpoint inhibitors Immune checkpoint inhibitor therapy-related pneumonitis: patterns and management Fatal toxic effects associated with immune checkpoint inhibitors: a systematic review and meta-analysis Severe cytokine release syndrome in a patient receiving PD-1-directed therapy Advances in the research of cytokine storm mechanism induced by corona virus disease 2019 and the corresponding immunotherapies Pathological findings of COVID-19 associated with acute respiratory distress syndrome Case of the index patient who caused tertiary transmission of COVID-19 infection in korea: the application of lopinavir/ritonavir for the treatment of COVID-19 infected pneumonia monitored by quantitative RT-PCR Clinical trial analysis of 2019-nCoV therapy registered in China Effective treatment of severe COVID-19 patients with tocilizumab Tocilizumab for the management of immune mediated adverse events secondary to PD-1 blockade A severe case of refractory esophageal stenosis induced by nivolumab and responding to tocilizumab therapy A systematic review on the emerging association between the occurrence of immune-related adverse events and clinical outcomes with checkpoint inhibitors in advanced cancer patients
    keywords: cancer; covid-19; ici; immune; patients; treatment
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        item: #4578 of 7819
          id: cord-312519-31mrmgmk
      author: Dauerman, Harold L.
       title: The Unbearable Thrombus of COVID-19: Primary PCI, Thrombus, and COVID-19
        date: 2020-09-08
       words: 445
      flesch: -2
     summary: Furthermore, the association of viral infection and enhanced risk of myocardial infarction has been described with respect to influenza, and an inflammatory mediation of risk is plausible (14, 15 High thrombus burden in patients with COVID-19 presenting with ST-segment elevation myocardial infarction ST-elevation myocardial infarction in patients with COVID-19: clinical and angiographic outcomes COVID-19-a case series Impact of coronavirus disease 2019 (COVID-19) outbreak on ST-segment-elevation myocardial infarction care in Hong Kong Reduction in ST-segment elevation cardiac catheterization laboratory activations in the United States during COVID-19 pandemic Effect of the COVID-19 pandemic on ST-segmentelevation myocardial infarction presentations and in-hospital outcomes Multivessel coronary thrombosis in a patient with COVID-19 pneumonia Angiographic stent thrombosis after routine use of drug-eluting stents in ST-segment elevation myocardial infarction: the importance of thrombus burden both epicardial and myocardial perfusion Management of acute myocardial infarction during the COVID-19 pandemic Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up: JACC state-ofthe-art review Inflammation and thrombosis: the clot thickens Acute myocardial infarction after laboratory-confirmed influenza infection Inflammation, immunity, and infection in atherothrombosis: JACC review topic of the week Hypercoagulability of COVID-19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis Risk of ischemic stroke in patients with coronavirus disease 2019 (COVID-19) vs patients with influenza And, the pathophysiology in 76, NO. 10, 2020 Multivessel thrombosis was seen in 17.9% of COVID-19 STEMI patients compared with none of the COVID-19-negative patients, as seen in a prior case report (7); stent thrombosis as the initial presentation was also 10 times more likely (p < 0.05 for both comparisons).
    keywords: covid-19; patients
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        item: #4579 of 7819
          id: cord-312558-w2vjuidm
      author: Gambardella, J.
       title: Exosomal microRNAs Drive Thrombosis in COVID-19
        date: 2020-06-18
       words: 903
      flesch: 39
     summary: Emerging evidence has shown that exosomal miRNAs are functionally involved in a number of physiologic and pathologic processes. To test the hypothesis that exosomal miRNAs are a key determinant of thrombosis in COVID-19, we enrolled patients positive for COVID-19.
    keywords: covid-19; exosomal; preprint
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        item: #4580 of 7819
          id: cord-312559-ygh507x2
      author: Fiesco-Sepulveda, K. Y.
       title: Contributions of Latin American researchers in the understanding the novel coronavirus outbreak: A literature review
        date: 2020-05-22
       words: 1892
      flesch: 44
     summary: 25.4%, 24.0%, and 12.6% of these national affiliations were from China, Europe, and the USA, respectively, making these regions leaders in COVID-19 research. Preparación y control de la enfermedad 772 por coronavirus 2019 (COVID-19) en América Latina Clinical trials on drug repositioning for COVID-19 treatment Will plant-made biopharmaceuticals play a role in the fight against 778 COVID-19?
    keywords: coronavirus; covid-19; license; manuscript; preprint; sars
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        item: #4581 of 7819
          id: cord-312609-gv1khfmo
      author: Fatima, Nida
       title: Impact of COVID-19 on neurological manifestations: an overview of stroke presentation in pandemic
        date: 2020-08-06
       words: 1850
      flesch: 38
     summary: The inclusion criteria included patients presenting with acute stroke who eventually were found to be positive COVID-19. Our systematic review determined the underlying risk factors leading to stroke among COVID-19 patients, and outcomes among these patients.
    keywords: covid-19; disease; patients; review; stroke
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        item: #4582 of 7819
          id: cord-312618-rxg7sjd9
      author: Allcott, Hunt
       title: Polarization and Public Health: Partisan Differences in Social Distancing during the Coronavirus Pandemic
        date: 2020-08-06
       words: 9689
      flesch: 56
     summary: Instead, we are asking, holding constant the amount of social distancing people are doing, would some people ideally be doing less, and others ideally be doing more? Next, we show that there exist individual-level partisan differences in (self-reported) social distancing behaviors and attitudes, consistent with the GPS analysis presented above.
    keywords: cases; counties; county; covid-19; data; differences; distancing; home; level; number; people; percent; republican; share
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        item: #4583 of 7819
          id: cord-312619-7jpf81yz
      author: Ilyas, Sadia
       title: Disinfection technology and strategies for COVID-19 hospital and bio-medical waste management
        date: 2020-08-12
       words: 5991
      flesch: 38
     summary: The awareness among the people can be a panacea for safer handling of COVID-waste, hence, the government, local bodies, waste treatment facilities must drive the awareness program using different media to directly reach out to the people. Notably, no books were found to exist until the search date (May 6, 2020) on COVID-19 waste; whereas, the reports and data published in webpages were found informative to shape this review article.
    keywords: collection; covid; covid-19; disinfection; disposal; guidelines; management; quarantine; sars; treatment; waste
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        item: #4584 of 7819
          id: cord-312623-ktswh3fu
      author: Werthman-Ehrenreich, Amanda
       title: Mucormycosis with orbital compartment syndrome in a patient with COVID-19
        date: 2020-09-16
       words: 1441
      flesch: 36
     summary: Amphotericin B was added for coverage of possible mucormycosis. On day 24 of hospitalization, repeat MRI of the brain showed previously noted regions of cerebral edema had evolved into multiple encapsulated complex fluid collections predominantly in the bifrontal region suspicious for invasive mucormycosis ( figure 5 and 6 ).
    keywords: covid-19; infection; mucormycosis; patient
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        item: #4585 of 7819
          id: cord-312632-g4250q6l
      author: Cai, Xiaofang
       title: Clinical Characteristics of 5 COVID-19 Cases With Non-respiratory Symptoms as the First Manifestation in Children
        date: 2020-05-12
       words: 4658
      flesch: 44
     summary: Although the patient had no fever or cough, because of a suspicion of contact history with COVID-19 patients (both parents and grandparents were suspected of having COVID-19), a chest CT scan was performed and showed bilateral lung pneumonia with local consolidation (Figures 5A,B) . Wang et al. reported that 10.1% of adult COVID-19 patients initially presented with diarrhea and nausea 1 to 2 days before the development of fever and dyspnea (10) .
    keywords: cases; children; coronavirus; cov-2; covid-19; disease; emergency; patients; sars; symptoms
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        item: #4586 of 7819
          id: cord-312677-rwznqiib
      author: Razmi, Mahdieh
       title: Immunomodulatory-Based Therapy as a Potential Promising Treatment Strategy against Severe COVID-19 Patients: A Systematic Review
        date: 2020-08-29
       words: 6565
      flesch: 33
     summary: A single center experience Tocilizumab treatment in severe COVID-19 patients attenuates the inflammatory storm incited by monocyte centric immune interactions revealed by single-cell analysis Favorable changes of CT findings in a patient with COVID-19 pneumonia after treatment with tocilizumab Off-label use of tocilizumab in patients with SARS-CoV-2 infection Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in severe patients with COVID-19 Tocilizumab therapy reduced intensive care unit admissions and/or mortality in COVID-19 patients Interleukin-6 blockade for severe COVID-19 Tocilizumab for the treatment of severe coronavirus disease 2019 Use of Tocilizumab for COVID-19-Induced Cytokine Release Syndrome: A Cautionary Case Report Acute hypertriglyceridemia in patients with COVID-19 receiving tocilizumab Tocilizumab for cytokine storm syndrome in COVID-19 pneumonia: an increased risk for candidemia? Use of siltuximab in patients with COVID-19 pneumonia requiring ventilatory support, medRxiv preprint Use of anakinra in severe COVID-19: a case report Targeting the inflammatory cascade with anakinra in moderate to severe COVID-19 pneumonia: case series Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord mesenchymal stem cells Treatment of Severe COVID-19 with human Umbilical Cord Mesenchymal Stem Cells Intravenous infusion of human umbilical cord Wharton's jellyderived mesenchymal stem cells as a potential treatment for patients with COVID-19 pneumonia Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-19 Effectiveness of convalescent plasma therapy in severe COVID-19 patients Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection Treatment with convalescent plasma for COVID-19 patients in Wuhan, China Use of Convalescent Plasma Therapy in Two COVID-19 Patients with Acute Respiratory Distress Syndrome in Korea High-Dose Intravenous Immunoglobulin as a Therapeutic Option for Deteriorating Patients With Coronavirus Disease Recovery of severely ill COVID-19 patients by intravenous immunoglobulin (IVIG) treatment: A case series Effect of regular intravenous immunoglobulin therapy on prognosis of severe pneumonia in patients with COVID-19 Clinical Efficacy of Intravenous Immunoglobulin Therapy in Critical Patients with COVID-19: WHO, Coronavirus disease 2019 (COVID-19) Situation Report -92 Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target Characteristics of and Public Health Responses to the Coronavirus Disease 2019 Outbreak in China Epidemiology, Pathogenesis, and Control of COVID-19 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA Quantifying SARS-CoV-2 transmission suggests epidemic control with digital contact tracing The correlation between viral clearance and biochemical outcomes of 94 COVID-19 infected discharged patients Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in COVID-19: immunopathology and its implications for therapy Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study COVID-19, immune system response, hyperinflammation and repurposing antirheumatic drugs Influence factors of death risk among COVID-19 patients in Wuhan, China: a hospital-based case-cohort study Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients Clinical features of patients infected with 2019 novel coronavirus in Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Effective treatment of severe COVID-19 patients with tocilizumab COVID-19 infection: the perspectives on immune responses Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure Clinical features and treatment of COVID-19 patients in northeast Chongqing Transplantation of ACE2(-)
    keywords: case; coronavirus; cov-2; covid-19; covid-19 patients; cytokine; disease; patients; sars; studies; study; therapy; treatment
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        item: #4587 of 7819
          id: cord-312678-81gnmxbk
      author: Elayeh, Eman
       title: Before and after case reporting: A comparison of the knowledge, attitude and practices of the Jordanian population towards COVID-19
        date: 2020-10-15
       words: 5443
      flesch: 48
     summary: Similarly, participants practice towards preventing transmission of COVID-19 score was calculated by assigning a score of one for appropriate practices, while inappropriate practices were assigned a score of zero. Hence, we rapidly adapted our study in order to engage more participants and to evaluate how this reported case altered the KAP of Jordanian citizens.
    keywords: case; covid-19; disease; knowledge; participants; practices; reporting; study
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        item: #4588 of 7819
          id: cord-312684-3i2r2ahr
      author: Iba, Toshiaki
       title: Coagulopathy in COVID‐19
        date: 2020-06-18
       words: 3637
      flesch: 35
     summary: [11] reported the reduced antithrombin activities in COVID-19 patients compared to healthy control (85% vs. 99%; p < 0.001), the activity was maintained above 80%. It is not known whether similar criteria are appropriate for COVID-19 patients.
    keywords: coagulation; coagulopathy; coronavirus; covid-19; infection; patients; sars; syndrome
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        item: #4589 of 7819
          id: cord-312702-fruzsn26
      author: Finch, Courtney L.
       title: Characteristic and quantifiable COVID-19-like abnormalities in CT- and PET/CT-imaged lungs of SARS-CoV-2-infected crab-eating macaques (Macaca fascicularis)
        date: 2020-05-14
       words: 2796
      flesch: 24
     summary: Based on the rather limited X-97 ray findings in the lungs of reported NHP models of SARS-CoV-2 infection with either 98 mild or no clinical signs (11, 25, 27-29), we turned to high-resolution chest CT and 99 PET/CT to characterize lung abnormalities in infected NHPs toward longitudinal 100 quantitative comparison. 161 CT images can be used for quantification of lung abnormalities using measures of 162 volume or radiodensity, i.e., total lung volume (LV); average radiodensity in the total 163 lung volume (LD); hyperdense volume (HV), a volume of lung in which radiodensity 164 (Hounsfield units, HU) is above a pre-defined threshold; and average radiodensity in the 165 hyperdense volume (hyperdensity, HD).
    keywords: abnormalities; coronavirus; covid-19; disease; lung; macaques; sars
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        item: #4590 of 7819
          id: cord-312721-e6532xrl
      author: Ruck, D. J.
       title: Cultural values predict national COVID-19 death rates
        date: 2020-07-17
       words: 1604
      flesch: 44
     summary: Applying a two-stage factor analysis to World and European Values Survey data [19, 20] we previously derived cultural value factors-including secularrationality (RAT), cosmopolitanism (COS) and institutional trust (INST)-in over one hundred countries key: cord-312721-e6532xrl authors: Ruck, D. J.; Borycz, J.; Bentley, R. A. title: Cultural values predict national COVID-19 death rates date: 2020-07-17 journal: nan DOI: 10.1101/2020.07.17.20156091 sha: doc_id: 312721 cord_uid: e6532xrl National responses to a pandemic require populations to comply through personal behaviors that occur in a cultural context.
    keywords: covid-19; figure; government; values
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        item: #4591 of 7819
          id: cord-312722-talu4geh
      author: Ahmed, Nausheen
       title: COVID-19 presenting as a viral exanthem and detected during admission prescreening in a hematopoietic cell transplant recipient
        date: 2020-06-13
       words: 1181
      flesch: 43
     summary: 9, 10 This atypical presentation of Covid-19 poses a diagnostic challenge in post-HCT patients due to potential misdiagnosis as GVHD. Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal Facing COVID-19 in the hematopoietic cell transplant setting: A new challenge for transplantation physicians COVID-19 Updates COVID-19 Reported Data ASTCT Interim Guidelines for Covid-19 Management in Hematopoietic Cell Transplant and Cellular Therapy Patients Version 1 Covid-19 and Kidney Transplantation European Society for Blood and Marrow Transplantation -EBMT Clinical Characteristics of Coronavirus Disease 2019 in China
    keywords: covid-19; patients; sars; transplant
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        item: #4592 of 7819
          id: cord-312730-4ejjmab4
      author: Wong, Rebecca S. Y.
       title: The SARS-CoV-2 Outbreak: an Epidemiological and Clinical Perspective
        date: 2020-09-29
       words: 6486
      flesch: 47
     summary: [43] whereas another study reported that HIV was associated with a doubling of mortality risk in COVID-19 patients medRxiv preprint 2020 Effects of temperature and humidity on the daily new cases and new deaths of COVID-19 in 166 countries The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells Pathogenesis of COVID-19 from a cell biology perspective Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Centre for Disease Control and Prevention SARS-Cov-2 infection: response of human immune system and possible implications for the rapid test and treatment Dysregulation of immune response in patients with coronavirus 2019 (COVID-19) in Wuhan, China Extrapulmonary and atypical clinical presentations of COVID-19 Extrapulmonary manifestations of COVID-19: radiologic and clinical overview Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicentre study Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases Cardiovascular disease and COVID-19 Epidemiological characteristics of 2143 paediatric patients with 2019 coronavirus disease in China Toxic shock-like syndrome and COVID-19: a case report of multisystem inflammatory syndrome in children (MIS-C) Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic Clinical analysis of ten pregnant women with COVID-19 in Wuhan, China: a retrospective study Clinical presentation and outcomes of pregnant women with COVID-19: a systematic review and meta-analysis Clinical features and outcomes of HIV patients with coronavirus disease 2019 HIV and risk of COVID-19 death: a population cohort study from the Western Cape Province, South Africa.
    keywords: cases; china; cov-2; covid-19; days; disease; patients; sars; study; transmission
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        item: #4593 of 7819
          id: cord-312748-9v2bmbod
      author: Guo, Zhen
       title: Anticoagulation Management in Severe COVID-19 Patients on Extracorporeal Membrane Oxygenation
        date: 2020-09-04
       words: 3126
      flesch: 28
     summary: In ECMO patients, acquired antithrombin deficiency is a result of hemodilution, initiation of coagulation cascade, and consumption due to the use of heparin. Criteria for antithrombin supplementation in adult ECMO patients are not well defined.
    keywords: antithrombin; coagulation; coronavirus; covid-19; ecmo; extracorporeal; patients; study; support
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        item: #4594 of 7819
          id: cord-312754-3yhxcfr2
      author: Allen, Bradley D.
       title: Society for Cardiovascular Magnetic Resonance (SCMR) guidance for re-activation of cardiovascular magnetic resonance practice after peak phase of the COVID-19 pandemic
        date: 2020-08-10
       words: 3681
      flesch: 31
     summary: COVID-19 positive patients will generally be at higher risk of transmitting the disease to healthcare workers and other patients. In COVID-19 positive patients, isolated waiting and changing areas are necessary.
    keywords: cardiovascular; cmr; covid-19; healthcare; imaging; pandemic; patients; research; time; workers
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        item: #4595 of 7819
          id: cord-312759-py2d4rjq
      author: Thiaw, Ibrahima
       title: Archaeology of Two Pandemics and Teranga Aesthetic
        date: 2020-08-25
       words: 2981
      flesch: 38
     summary: This was reflected in many early western discourses, French in particular, about the pandemic in Africa. Building on archaeology’s multiple contributions to Africa’s past and observed practices of resilience in Senegal by ordinary people in the face of the spread of COVID-19, this essay reflects on the relevance of the archives, including the archaeological record, as usable resources for managing the problems of our times.
    keywords: africa; colonial; covid-19; discourses; france; pandemic; practices; senegalese; teranga
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        item: #4596 of 7819
          id: cord-312777-5925lvue
      author: Pan, Feng
       title: Different computed tomography patterns of Coronavirus Disease 2019 (COVID-19) between survivors and non-survivors
        date: 2020-07-09
       words: 3651
      flesch: 43
     summary: Initial symptoms were similar between survivor and non-survivor groups, whilst chest distress was more common in non-survivor group. From the prediction of curve estimation, in survivor group total CT score increased in the first 20 days reaching a peak of 6 points and then gradually decreased for more than other 40 days (R(2) = 0.545, p < 0.001).
    keywords: chest; covid-19; days; group; non; patients; survivor
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        item: #4597 of 7819
          id: cord-312784-ykko0al5
      author: Takian, Amirhossein
       title: COVID-19 battle during the toughest sanctions against Iran
        date: 2020-03-18
       words: 1299
      flesch: 45
     summary: However, we request that the government urgently and openly shares the scientific evidence, data, and models it is using to inform current decision making related to COVID-19 public health interventions within the next 72 h and then at regular intervals thereafter. Vol 395 March 28, 2020 of the disease and evidence pertaining to effective public health interventions is increasingly available.
    keywords: covid-19; health; pandemic; sanctions
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        item: #4598 of 7819
          id: cord-312795-0e4esl2o
      author: Puig-Domingo, M.
       title: COVID-19 and endocrine diseases. A statement from the European Society of Endocrinology
        date: 2020-04-11
       words: 2639
      flesch: 38
     summary: Increased risk of morbidity and mortality in patients with diabetes regarding COVID-19 infection Older adults and those with serious chronic medical conditions like heart disease, lung disease, and diabetes are at the highest risk for complications from COVID-19 infection. This is also the case for COVID-19 infection [1] .
    keywords: covid-19; diabetes; disease; infection; patients; risk
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        item: #4599 of 7819
          id: cord-312798-2cbgnv1h
      author: Varma, Niraj
       title: HRS/EHRA/APHRS/LAHRS/ACC/AHA worldwide practice update for telehealth and arrhythmia monitoring during and after a pandemic
        date: 2020-06-11
       words: 3549
      flesch: 29
     summary: In COVID-19 patients receiving prior antiarrhythmic therapy, there should be a thorough consideration of risk vs benefit before initiating any QT-prolonging COVID-19 therapies, especially considering their unproven value. Clinical characteristics of Covid-19 in New York City Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) Transient complete heart block in a patient with critical COVID-19 A young woman presenting with a viral prodrome, palpitations, dizziness, and heart block Cardiac and arrhythmic complications in patients with COVID-19 Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19) Guidance on minimizing risk of drug-induced ventricular arrhythmia during treatment of COVID-19: a statement from the Canadian Heart Rhythm Society How to protect the protectors: 10 lessons to learn for doctors fighting the COVID-19 coronavirus Inpatient use of mobile continuous telemetry for COVID-19 patients treated with hydroxychloroquine and azithromycin ISHNE-HRS expert consensus statement on ambulatory ECG and external cardiac monitoring/telemetry Comparison of QT interval readings in normal sinus rhythm between a smartphone heart monitor and a 12-lead ECG for healthy volunteers and inpatients receiving sotalol or dofetilide A wearable remote monitoring system for the identification of subjects with a prolonged QT interval or at risk for drug-induced long QT syndrome Can smartphone wireless ECGs be used to accurately assess ECG intervals in pediatrics?
    keywords: care; covid-19; ecg; health; hydroxychloroquine; monitoring; patients; qtc; risk
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        item: #4600 of 7819
          id: cord-312801-tllj77up
      author: Giovannoni, Gavin
       title: The COVID-19 pandemic and the use of MS disease-modifying therapies
        date: 2020-03-27
       words: 3057
      flesch: 40
     summary: Another hypothesis being considered is that moderate immunosuppression may prevent severe complications associated with COVID-19 infection. The severe pulmonary complications of COVID-19 infection are consistent with ARDS (acute respiratory distress syndrome) caused by an over-exuberant immune response to the virus (Ramanathan et al., 2020) .
    keywords: covid-19; infection; patients; risk; sclerosis
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        item: #4601 of 7819
          id: cord-312812-3ghm9qy0
      author: Ziadé, Nelly
       title: The impact of COVID-19 pandemic on rheumatology practice: a cross-sectional multinational study
        date: 2020-09-30
       words: 4082
      flesch: 39
     summary: The current study highlights the deleterious consequences of the COVID-19 pandemic on the rheumatology practice by Work with health authorities to guarantee the availability of drugs for patients with chronic rheumatic diseases 2 Telemedicine platform Discuss the modalities of telemedicine and its legal framework of implementation in the Arab region 3 Personal protective equipment Work with health authorities to guarantee the availability of personal protective equipment for health care professionals 4 Patient education Develop unified guidance for rheumatology patients during the pandemic and the transitional deconfinement period Promote channels of patients' education and advocacy for rheumatology 5 Medical education Develop unified practice guidelines for the rheumatologists in the Arab region during the pandemic and the transitional deconfinement period key: cord-312812-3ghm9qy0 authors: Ziadé, Nelly; Hmamouchi, Ihsane; el Kibbi, Lina; Abdulateef, Nizar; Halabi, Hussein; Abutiban, Fatemah; Hamdi, Wafa; el Rakawi, Manal; Eissa, Mervat; Masri, Basel title: The impact of COVID-19 pandemic on rheumatology practice: a cross-sectional multinational study date: 2020-09-30 journal: Clin Rheumatol DOI: 10.1007/s10067-020-05428-2 sha: doc_id: 312812 cord_uid: 3ghm9qy0 OBJECTIVE: To evaluate the impact of the coronavirus disease 2019 (COVID-19) pandemic on rheumatology practice.
    keywords: arab; covid-19; impact; pandemic; patients; practice; rheumatologists; rheumatology; telemedicine
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        item: #4602 of 7819
          id: cord-312826-4m54ve8v
      author: HOERTEL, N.
       title: Observational Study of Haloperidol in Hospitalized Patients with Covid-19
        date: 2020-07-20
       words: 3952
      flesch: 43
     summary: 15.20150490 doi: medRxiv preprint In this report, we examined the association between haloperidol use and respiratory failure among adult patients with Covid-19 who have been hospitalized in these medical centers. Conclusion: In this observational study involving patients with Covid-19 who had been admitted to the hospital, haloperidol use was not associated with risk of intubation or death, or with time to hospital discharge home.
    keywords: covid-19; haloperidol; medrxiv; number; patients; preprint; review
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        item: #4603 of 7819
          id: cord-312835-a60bkohc
      author: Kohli, Utkarsh
       title: Fulminant myocarditis and atrial fibrillation in child with acute COVID-19
        date: 2020-10-18
       words: 834
      flesch: 24
     summary: However, very few pediatric patients with acute COVID-19 have had cardiac involvement. We report a 15 year-old girl with acute COVID-19, fulminant myocarditis and AFib.
    keywords: children; covid-19; fibrillation
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        item: #4604 of 7819
          id: cord-312847-2cg3ylfl
      author: Carter, Chris
       title: COVID-19 Disease: assessment of a critically ill patient
        date: 2020-06-01
       words: 5891
      flesch: 44
     summary: Part 3: cultural and behavioural factors Critical care outreach: capturing nurses' contributions Communication as a basic skill in critical care COVID-19: a synthesis of clinical experience in UK intensive care settings Clinical guide for the management of critical care patients during the coronavirus pandemic Role of air distribution in SARS transmission during the largest nosocomial outbreak in Hong Kong Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected Unintentional endotracheal tube cuff deflation during routine checks: a simulation study A nurse's survival guide to critical care Optimizing oxygenation in the mechanically ventilated patient Practical recommendations for critical care and anesthesiology teams caring for novel coronavirus (2019-nCoV) patients Critical care nursing made incredibly easy Patient Safety: Pulse Oximetry Training Manual Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Clinical characteristics of coronavirus disease 2019 in China Clinical characteristics of 140 patients infected by SARS-CoV-2 in Wuhan Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Cardiac monitoring and the use of a systematic approach in interpreting electrocardiogram rhythms Undertaking an accurate and comprehensive assessment of the acutely ill adult Assessing acutely ill patients on general wards Attention should be paid to venous thromboembolism prophylaxis in the management of COVID-19 COVID-19: consider cytokine storm syndromes and immunosuppression Best practices for managing pain, sedation and delirium in the mechanically ventilated patient Early mobilization of mechanically ventilated patients. 8 A major change in the assessment process is that COVID-19 patients may be initially assessed by redeployed staff and not a qualified Critical Care Nurse.
    keywords: assessment; blood; care; clinical; covid-19; disease; pain; patients; position; pressure; risk; score; signs; ventilation
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        item: #4605 of 7819
          id: cord-312849-vgzvpwz9
      author: Eckbo, Eric J.
       title: Evaluation of the BioFire® COVID-19 Test and Respiratory Panel 2.1 for Rapid Identification of SARS-CoV-2 in Nasopharyngeal Swab Samples
        date: 2020-11-10
       words: 1424
      flesch: 37
     summary: The COVID-19 Test was developed with funding from the U.S. Department of Defense, and detects three targets within the open reading frame (ORF) region of the viral genome (5) . The guidelines highlight the fact that a knowledge gap currently exists regarding the use of rapid tests (defined as turnaround time ≤ 1 hour) versus standard RNA tests in terms of performance characteristics, and therefore makes no recommendations for or against them.
    keywords: assays; biofire; covid-19; test
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        item: #4606 of 7819
          id: cord-312861-6ayidmj3
      author: Rayner, Craig R.
       title: Accelerating Clinical Evaluation of Repurposed Combination Therapies for COVID-19
        date: 2020-08-21
       words: 2001
      flesch: 24
     summary: Adaptive platform trials provide capacity in combination trials to add or remove ineffective treatment arms, allowing for sequential comparisons and a perpetual design wherein treatments can be prioritized or de-prioritized as evidence accumulates. Among options for accelerated development is the evaluation of drug combinations in the absence of prior monotherapy data.
    keywords: approach; combination; covid-19; treatment; trials
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        item: #4607 of 7819
          id: cord-312864-km07zhn1
      author: Potalivo, A.
       title: Sixty-day mortality among 520 Italian hospitalized COVID-19 patients according to the adopted ventilatory strategy in the context of an integrated multidisciplinary clinical organization: a population-based cohort study
        date: 2020-08-15
       words: 5412
      flesch: 46
     summary: key: cord-312864-km07zhn1 authors: Potalivo, A.; Montomoli, J.; Facondini, F.; Sanson, G.; Lazzari Agli, L. A.; Perin, T.; Cristini, F.; Cavagna, E.; De Giovanni, R.; Biagetti, C.; Panzini, I.; Ravaiolo, C.; Bitondo, M.; Guerra, D.; Giuliani, G.; Mosconi, E.; Guarino, S.; Marchionni, E.; Gangitano, G.; Valentini, I.; Giampaolo, L.; Muratori, F.; Nardi, G. title: Sixty-day mortality among 520 Italian hospitalized COVID-19 patients according to the adopted ventilatory strategy in the context of an integrated multidisciplinary clinical organization: a population-based cohort study date: 2020-08-15 journal: nan DOI: 10.1101/2020.08.13.20174615 sha: doc_id: 312864 cord_uid: km07zhn1 Background: Among COVID-19 patients, the decision of which ventilation strategy to adopt is crucial and not guided by existing outcome evidence. The percentage of COVID-19 patients requiring non-invasive (NIV) or invasive mechanical ventilation (IMV) is unclear and strongly affected by the hospital organization and the availability of resources.
    keywords: covid-19; days; icu; imv; mortality; niv; oxygen; patients; study
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        item: #4608 of 7819
          id: cord-312884-anlp8lab
      author: Iyer, Gayatri R.
       title: Infectivity and Progression of COVID-19 Based on Selected Host Candidate Gene Variants
        date: 2020-09-04
       words: 6281
      flesch: 33
     summary: Maximum number of variants (n = 390) were identified in MUC5B gene and the least (n = 17) in ACE2 gene. In TMPRSS2 gene 81 variants were identified and the most common polymorphism identified was rs140530035 (18/103), followed by rs422471 (14/103) and rs464431 (10/103).
    keywords: ace2; covid-19; disease; et al; gene; ifitm3; individuals; infection; influenza; muc5b; polymorphisms; sars; study; tmprss2; variants
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        item: #4609 of 7819
          id: cord-312885-d4ku8dyz
      author: Wang, W.
       title: Global, regional, and national estimates of target population sizes for COVID-19 vaccination
        date: 2020-09-30
       words: 4380
      flesch: 37
     summary: Results Overall, the size of COVID-19 vaccine recipient population varied markedly by goals of the vaccination program and geography. Overall, the size of COVID-19 vaccine recipient population varied markedly by goals of the vaccination program and geography.
    keywords: covid-19; medrxiv; population; preprint; review; target; vaccination; vaccine
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        item: #4610 of 7819
          id: cord-312905-8xlt92pl
      author: Li, Guanjian
       title: Asymptomatic and Presymptomatic Infectors: Hidden Sources of COVID-19 Disease
        date: 2020-04-09
       words: 690
      flesch: 44
     summary: At the time of writing this paper, the authors claimed that evidence regarding transmission from individuals with asymptomatic infection or mild illness is limited, but that the current evidence may need an update. Their conclusion is that the virus infection rates of close contacts were 6.30% (contact with symptomatic patients) and 4.11% (contact with asymptomatic patients), respectively.
    keywords: covid-19
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        item: #4611 of 7819
          id: cord-312918-iof45k1r
      author: Ortolani, Claudio
       title: Hydroxychloroquine and dexamethasone in COVID-19: who won and who lost?
        date: 2020-09-09
       words: 4649
      flesch: 40
     summary: These three ‘Recovery’ RCTs concluded definitely: (a) that treatment with hydroxychloroquine provides no benefits in patients hospitalized with COVID-19; (b) that treatment with dexamethasone reduced deaths by one-third in COVID-19 patients that were mechanically ventilated, and by one-fifth in patients receiving oxygen only; (c) that the combination of Lopinavir and Ritonavir is not effective in reducing mortality in COVID-19 hospitalized patients. Given the importance of resolving this disparity of opinion, it was essential to carry out randomized and controlled studies on a large sample of COVID-19 patients evaluating the results in relation to the severity of the disease.
    keywords: clinical; cov-2; covid-19; dexamethasone; hydroxychloroquine; patients; results; sars; study; treatment
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        item: #4612 of 7819
          id: cord-312926-j9jybblr
      author: Dong, W.
       title: Early Awake Prone and Lateral Position in Non-intubated Severe and Critical Patients with COVID-19 in Wuhan: A Respective Cohort Study
        date: 2020-05-13
       words: 3461
      flesch: 51
     summary: One of the pathophysiological features of ARDS in severe patients is lung inhomogeneity. According to the findings in China, about 14% of COVID-19 patients were severe and 5% were criticaland the overall case-fatality rate among critical cases reached 49.0%.
    keywords: covid-19; license; patients; preprint
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        item: #4613 of 7819
          id: cord-312955-gs65c3fy
      author: Schreiber, Gideon
       title: The Role of Type I Interferons in the Pathogenesis and Treatment of COVID-19
        date: 2020-09-30
       words: 8440
      flesch: 38
     summary: These data show that tight binding IFN-Is induce preferential anti-inflammatory responses, at least in this MS mouse model. Front Immunol DOI: 10.3389/fimmu.2020.595739 sha: doc_id: 312955 cord_uid: gs65c3fy Type I interferons (IFN-I) were first discovered over 60 years ago in a classical experiment by Isaacs and Lindenman, who showed that IFN-Is possess antiviral activity.
    keywords: binding; cells; cov-2; covid-19; disease; ifn; ifnb; immune; interferon; patients; production; receptor; response; sars; treatment; type
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        item: #4614 of 7819
          id: cord-312960-i3l8lh4e
      author: Almeshari, M. A.
       title: Mechanical ventilation utilization in COVID-19: A systematic review and meta-analysis
        date: 2020-06-05
       words: 4622
      flesch: 50
     summary: Studies were considered for inclusion if they used IMV as part of the treatment of COVID-19 patients. A narrative synthesis was carried out to assess the proportion of COVID-19 patients requiring invasive mechanical ventilation, when IMV was initiated after symptom onset, and for how long patients received IMV until either clinical improvement or death.
    keywords: covid-19; imv; license; medrxiv; patients; perpetuity; preprint; studies
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        item: #4615 of 7819
          id: cord-312969-r8vt2i2z
      author: Temgoua, Mazou Ngou
       title: COVID-19 pandemic: do we need systematic screening of patients with cardiovascular risk factors in Low and Middle-Income Countries (LMICs) for preventing death?
        date: 2020-04-29
       words: 866
      flesch: 45
     summary: In Low and Middle-Income Countries (LMICs), like all over the world, there is an increased spread of the COVID-19 [9] and high burden of cardiovascular diseases [10] ; but until now there is no political strategy to screen systematically patients with cardiovascular risk factors for early management. We think that systematic screening of COVID-19 in patient with cardiovascular risk factors or established cardiovascular diseases could help to reduce the burden of the disease in this continent.
    keywords: covid-19; disease; patients
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        item: #4616 of 7819
          id: cord-312986-nz8uc7sl
      author: Abou-Abbas, Linda
       title: Knowledge and practice of physicians during COVID-19 pandemic: a cross-sectional study in Lebanon
        date: 2020-09-29
       words: 3811
      flesch: 49
     summary: Our survey revealed that the majority of Lebanese physicians had good knowledge about the disease (89.5%) while approximately half of the respondents adopted good preventive practices (49.7%). Lebanese physicians revealed a good level of knowledge; however, they had limited comprehension of the precautionary measures that protect them from this virus.
    keywords: care; covid-19; disease; health; knowledge; physicians; practice; survey
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        item: #4617 of 7819
          id: cord-313071-9nm460b0
      author: Xu, M.
       title: Accurately Differentiating COVID-19, Other Viral Infection, and Healthy Individuals Using Multimodal Features via Late Fusion Learning
        date: 2020-08-21
       words: 8574
      flesch: 43
     summary: A more comprehensive definition and description of clinical features were provided in supplementary table SI1. We compared clinical features across four classes.
    keywords: classes; clinical; covid-19; data; features; license; medrxiv; models; non; patients; preprint; study; testing
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        item: #4618 of 7819
          id: cord-313082-n3bo9jw1
      author: Tenenbein, Paul
       title: The case for routine screening for SARS-CoV-2 before surgery
        date: 2020-06-03
       words: 3819
      flesch: 44
     summary: La plupart des interventions chirurgicales nécessitent une intubation/extubation et d'autres interventions médicales générant des aérosols, ce qui augmente le risque de transmission nosocomiale aux travailleurs de la santé qui prennent soin du patient pendant et après la chirurgie. suffisamment précis pour altérer la prise en charge du patient et les précautions de contrôle des infections.
    keywords: chirurgie; cov-2; covid-19; des; les; patients; que; sars; surgery; test; testing
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        item: #4619 of 7819
          id: cord-313084-l7odplqg
      author: Sampson, Victoria
       title: Could there be a link between oral hygiene and the severity of SARS-CoV-2 infections?
        date: 2020-06-26
       words: 3355
      flesch: 35
     summary: Lower respiratory infection is initiated by the contamination of the lower airway epithelium by inhalation of microorganisms encompassed in aerosolised droplets, or by aspiration of oral secretions associated with oral disease (containing microorganisms such as P. gingivalis, F. nucleatum, P. intermedia). This is supported by a country report covering Italy, showing that 96.5% of complications arising from COVID-19 infection were ARDS, followed by acute renal failure (29.2%).
    keywords: complications; covid-19; disease; infection; patients; pneumonia; risk
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        item: #4620 of 7819
          id: cord-313117-0qur0isb
      author: Gardinassi, Luiz G.
       title: Immune and Metabolic Signatures of COVID-19 Revealed by Transcriptomics Data Reuse
        date: 2020-06-26
       words: 3566
      flesch: 25
     summary: Front Immunol Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients A dynamic immune response shapes COVID-19 progression Imbalanced host response to SARS-CoV-2 drives development of COVID-19 Heightened innate immune responses in the respiratory tract of COVID-19 patients Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles edgeR: a Bioconductor package for differential expression analysis of digital gene expression data Expanding the immunology toolbox: embracing public-data reuse and crowdsourcing Expression profile of immune response genes in patients with Severe Acute Respiratory Syndrome Plasticity and virus specificity of the airway epithelial cell immune response during respiratory virus infection Gene expression patterns in blood leukocytes discriminate patients with acute infections Aberrant cell cycle and apoptotic changes characterise severe influenza To address such issues, recent studies have reported transcriptomic profiles of cells, tissues and fluids from COVID-19 patients that mainly demonstrated activation of humoral immunity, dysregulated type I and III interferon expression, intense innate immune responses and inflammatory signaling.
    keywords: cov-2; covid-19; data; expression; gene; infection; patients; sars
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        item: #4621 of 7819
          id: cord-313148-dps5dyhr
      author: Nkhata, Smith G.
       title: SARS-CoV 2 (Covid-19) Heterogeneous Mortality Rates across Countries May Be Partly Explained by Life Expectancy, Calorie Intake, and Prevalence of Diabetes.
        date: 2020-10-21
       words: 2733
      flesch: 40
     summary: Therefore it should not be interpreted as indicative that lower pollution is potentially associated with higher Covid-19 mortality. Higher Covid-19 mortality rates are reported in countries with high life expectancy (>70 years) than those countries with lower (<70 years) life expectancy (Verity et al. 2020) .
    keywords: countries; covid-19; factors; life; mortality
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        item: #4622 of 7819
          id: cord-313151-coqbcrwc
      author: Sarkodie, Samuel Asumadu
       title: Global assessment of environment, health and economic impact of the novel coronavirus (COVID-19)
        date: 2020-06-05
       words: 3370
      flesch: 40
     summary: The intensity of the global pandemic (COVID-19) has affected global economic development, resulting in several fiscal measures, monetary policies and private sector economic burden-sharing across countries. The global distribution of economic policy response to COVID-19 across 166 countries is presented in Fig.
    keywords: coronavirus; countries; covid-19; gdp; health; level; measures; pandemic; policy; social
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        item: #4623 of 7819
          id: cord-313157-wzz3dasn
      author: Rodríguez-Chagolla, José M.
       title: Peritoneal Dialysis Is an Option for Acute Kidney Injury Management in Patients with COVID-19
        date: 2020-10-05
       words: 4150
      flesch: 43
     summary: In an environment where optimizing resources is relevant, increasing availability of PD patients, percutaneous catheter insertion with and without image guidance can be performed at bedside by surgeons' interventional radiologists and nephrologists and may be considered for peritoneal access [35] . 3D8*s ortby%3D2*label%3D19791 Peritoneal dialysis for acute kidney injury treatment in the United States: brought to you by the COVID-19 pandemic Peritoneal dialysis for COVID-19-associated acute kidney injury Best practices consensus protocol for peritoneal dialysis catheter placement by interventional radiologists Percutaneous peritoneal dialysis catheter insertion by a nephrologist: a new, simple, and safe technique ISPD peritonitis recommendations: 2016 update on prevention and treatment Strategies regarding COVID-19 in PD patients, Adapted from Peking University First Hospital Centers for Disease Control and Prevention.
    keywords: acute; aki; covid-19; dialysis; disease; injury; kidney; patients; rrt
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        item: #4624 of 7819
          id: cord-313215-diqfmitr
      author: Luo, Lei
       title: Air and surface contamination in non-health care settings among 641 environmental specimens of 39 COVID-19 cases
        date: 2020-07-09
       words: 1594
      flesch: 43
     summary: We highly recommend that persons no matter COVID-19 cases or Note: Environmental specimens were tested by RT-PCR testing; 5 positive environmental specimens of asymptomatic COVID-19 cases were excluded in bars of symptoms onset to sampling. key: cord-313215-diqfmitr authors: Luo, Lei; Liu, Dan; Zhang, Hao; Li, Zhihao; Zhen, Ruonan; Zhang, Xiru; Xie, Huaping; Song, Weiqi; Liu, Jie; Huang, Qingmei; Liu, Jingwen; Yang, Xingfen; Chen, Zongqiu; Mao, Chen title: Air and surface contamination in non-health care settings among 641 environmental specimens of 39 COVID-19 cases date: 2020-07-09 journal: bioRxiv DOI: 10.1101/2020.07.09.195008 sha: doc_id: 313215 cord_uid: diqfmitr Background Little is known about the SARS-CoV-2 contamination of environmental surfaces and air in non-health care settings among COVID-19 cases.
    keywords: cases; covid-19; specimens; surfaces
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        item: #4625 of 7819
          id: cord-313237-ai39ny9y
      author: Abdullah, Jafri Malin
       title: A Critical Appraisal of COVID-19 in Malaysia and Beyond
        date: 2020-04-10
       words: 2433
      flesch: 44
     summary: The Star South Korea is reporting intimate details of COVID-19 cases: has it helped? According the most recent data on COVID-19 study among 1,210 respondents from 194 cities in China (20), more than half of the respondents suffered moderate to severe psychological impacts; of those, 28.8% had moderate to severe anxiety, 16.5% had moderate to severe depressive symptoms and 8.1% had moderate to severe stress levels.
    keywords: china; coronavirus; countries; covid-19; disease; health; malaysia; pandemic
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        item: #4626 of 7819
          id: cord-313239-0gl43af5
      author: Moreno, Courtney C.
       title: CT colonography’s role in the COVID-19 pandemic: a safe(r), socially distanced total colon examination
        date: 2020-08-03
       words: 2825
      flesch: 38
     summary: Guidance from the Centers for Disease Control and Prevention and directives from state officials resulted in the postponement of elective procedures including cancer screening at facilities to prevent community spread and to preserve the healthcare workforce, facilities, and personal protective equipment (PPE) for an anticipated surge of COVID-19 patients [2] . Though undesirable at any time, a screening procedure-associated perforation is especially undesirable in the COVID-19 era as it would result in unnecessary hospitalization, utilization of healthcare resources, and potential patient exposure to hospitalized COVID-19 patients.
    keywords: cancer; colonoscopy; covid-19; ctc; healthcare; pandemic; patients; screening
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        item: #4627 of 7819
          id: cord-313267-dc8z4jzo
      author: Daneshkhah, Ali
       title: The Role of Vitamin D in Suppressing Cytokine Storm in COVID-19 Patients and Associated Mortality
        date: 2020-04-10
       words: 5003
      flesch: 51
     summary: Patient-level CRP data were used as a surrogate marker of cytokine storm and its link and association with Vit D status was used to suggest a potential link between Vit D severe deficiency and the number severe COVID-19 cases. Clinical data obtained from COVID-19 patients in China reported high concentrations of cytokines such as GCSF, IP10, MCP1, MIP1A, and TNFα in patients admitted to the ICU, which indicates the presence of cytokine storm in severe COVID-19 cases [6] .
    keywords: age; countries; covid-19; data; patients; ratio; risk; system; vit
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        item: #4628 of 7819
          id: cord-313268-j51zyodw
      author: Zeng, Xiangxiang
       title: Repurpose Open Data to Discover Therapeutics for COVID-19 Using Deep Learning
        date: 2020-07-12
       words: 4091
      flesch: 34
     summary: In this study, we present the state-of-the-art knowledge-graph-based, deep-learning methodologies for the rapid discovery of drug candidates to treat COVID-19 from 24 million PubMed publications ( Figure 1 ). 55 To fight the emerging COVID-19 pandemic, we introduced an integrative, network-based, deep-learning methodology to discover candidate drugs for COVID-19, named CoV-KGE.
    keywords: cov-2; covid-19; data; drugs; human; kge; patients; sars; set; treatment
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        item: #4629 of 7819
          id: cord-313272-lkzo10r5
      author: Bellini, Carlo
       title: Neonatal Transport and COVID-19 outbreak
        date: 2020-03-31
       words: 573
      flesch: 38
     summary: All the findings listed previously cannot be linked exclusively to COVID-19 infection during neonatal age. Because infants have an immature immune system and the route of vertical transmission cannot be surely ruled out, newborns are a high-risk group for infection, thus growing the complexity of neonatal transport (figure).
    keywords: covid-19; transport
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        item: #4630 of 7819
          id: cord-313275-znrvkmee
      author: Bwire, G. M.
       title: A systematic review on the levels of antibodies in COVID-19 virus exposed but negative newborns: a possible vertical transmission of IgG/ IgM
        date: 2020-06-12
       words: 2967
      flesch: 48
     summary: WHO Clinical management of severe acute respiratory infection (SARI) when COVID-19 disease is suspected Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study Antibodies in Infants Born to Mothers With COVID-19 Pneumonia Tests for IgG and IgM antibodies for severe acute respiratory Training and Fit Testing of Health Care Personnel for Reusable Elastomeric Half-Mask Respirators Compared With Disposable N95 Respi Delivery in Asymptomatic Italian Woman with SARS-CoV-2 Infection Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis key: cord-313275-znrvkmee authors: Bwire, G. M.; Njiro, B. J. title: A systematic review on the levels of antibodies in COVID-19 virus exposed but negative newborns: a possible vertical transmission of IgG/ IgM date: 2020-06-12 journal: nan DOI: 10.1101/2020.06.09.20127118 sha: doc_id: 313275 cord_uid: znrvkmee Background Currently, there is no doubt on human-to-human transmission of Coronavirus Disease 2019 (COVID-19).
    keywords: cov-2; igm; license; medrxiv; preprint
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        item: #4631 of 7819
          id: cord-313282-z5cues67
      author: Schaefer, Inga-Marie
       title: In situ detection of SARS-CoV-2 in lungs and airways of patients with COVID-19
        date: 2020-06-19
       words: 3981
      flesch: 35
     summary: A Prospective Cohort Study Pulmonary arterial thrombosis in COVID-19 with fatal outcome: results from a prospective, single-center, clinicopathologic case series Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19 Comparison of SARS-CoV-2 Detection from Nasopharyngeal Swab Samples by the Roche Cobas 6800 SARS-CoV-2 test and a laboratory-developed real-time RT-PCR test Early detection of SARS-CoV-2 antibodies in COVID-19 patients as a serologic marker of infection Interpreting diagnostic tests for SARS-CoV-2 A serological assay to detect SARS-CoV-2 seroconversion in humans Antibody responses to SARS-CoV-2 in patients with COVID-19 COVID-19: progression of disease and intravascular coagulation-present status and future perspectives SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes Respiratory disease in rhesus macaques inoculated with SARS-CoV-2 Pathology and pathogenesis of SARS-CoV-2 associated with fatal coronavirus disease, United States SARS-CoV-2 infection protects against rechallenge in rhesus macaques Time course and cellular localization of SARS-CoV nucleoprotein and RNA in lungs from fatal cases of SARS Endothelial cell infection and endotheliitis in COVID-19 COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages COVID-19 with silent hypoxemia Silent hypoxia: a harbinger of clinical deterioration in patients with COVID-19 Compassionate use of remdesivir for patients with severe Covid-19 Distinct patterns of primary and motile cilia in Rathke's cleft cysts and craniopharyngioma subtypes Effects of paramyxoviral infection on airway epithelial cell Foxj1 expression, ciliogenesis, and mucociliary function Respiratory syncytial virus inhibits ciliagenesis in differentiated normal human bronchial epithelial cells: effectiveness of N-acetylcysteine Murine cytomegalovirus influences Foxj1 expression, ciliogenesis, and mucus plugging in mice with allergic airway disease Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19 The pulmonary vascular lesions of the adult respiratory distress syndrome Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: A Report of 1014 Overall, the different stages of DAD observed histologically correspond to the estimated time interval from onset of respiratory failure to death; however, the exact timing of severe lung injury may be difficult to determine in certain cases given reports of silent hypoxemia in COVID-19 infected patients [27, 28] .
    keywords: autopsy; cells; covid-19; dad; days; fig; infection; lung; patients; sars
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        item: #4632 of 7819
          id: cord-313286-nqvuas3p
      author: Afshar Jahanshahi, A.
       title: The distress of Iranian adults during the Covid-19 pandemic - More distressed than the Chinese and with different predictors
        date: 2020-04-07
       words: 1972
      flesch: 51
     summary: The Covid-19 outbreak first triggered public panic and mental health distress in China 2 . Adults who were unsure whether they had Covid-19 reported higher distress than those who reported being free from the disease (β=-8.91, p=0.000, 95% CI -11.26 to -6.57).
    keywords: adults; covid-19; distress; iran
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        item: #4633 of 7819
          id: cord-313294-ffgo56gl
      author: Bertsimas, D.
       title: Personalized Prescription of ACEI/ARBs for Hypertensive COVID-19 Patients
        date: 2020-11-04
       words: 7317
      flesch: 41
     summary: Pharmacologic treatments for coronavirus disease 2019 (covid-19): a review A multivariate analysis of genomic polymorphisms: prediction of clinical outcome to 5-FU/oxaliplatin combination chemotherapy in refractory colorectal cancer Estimation and inference of heterogeneous treatment effects using random forests Good or bad: application of raas inhibitors in covid-19 patients with cardiovascular comorbidities Remdesivir in adults with severe covid-19: a randomised, double-blind, placebo-controlled, multicentre trial WHO (2020) The derivation cohort is comprised of data from 2,842 hypertensive patients from HOPE registry's hospitals in Spain and from HM Hospitals, also in Spain is the author/funder, who has granted medRxiv a license to display the preprint in (which was not certified by peer review) preprint Match treated and untreated populations based on clinical features and other treatments.
    keywords: acei; arbs; covid-19; data; models; morbidity; mortality; patients; preprint; prescription; rate; risk; treatment
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        item: #4634 of 7819
          id: cord-313313-twct29aq
      author: Carbonell, Ana Piera
       title: Trombosis y covid-19: atención primaria clave en el abordaje interdisciplinar
        date: 2020-06-06
       words: 938
      flesch: 34
     summary: no presencial y consultas telemáticas, permitiendo seguimiento clínico evolutivo de forma efectiva, reforzando la autogestión de la salud de cada individuo y su familia. La radiografía de tórax realizada muestra aumento de la trama broncovascular
    keywords: con; covid-19; por; que
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        item: #4635 of 7819
          id: cord-313353-uwwih8v3
      author: Di Tano, Giuseppe
       title: Late Pulmonary Embolism after COVID-19 Pneumonia despite Adequate Rivaroxaban Treatment
        date: 2020-06-18
       words: 1337
      flesch: 35
     summary: Autopsy specimens from COVID-19 patients showed that pulmonary arteries at the hilum were free of thromboemboli, whereas small-vessel thrombus formation was seen in the periphery of the lung parenchyma in the majority of cases, supporting the concept of a hypercoagulative status, and a high frequency of pulmonary micro-thrombosis [6, 7] . This case highlights the risk of thrombotic complications after COVID-19 infection, raises some concern about their underlying mechanisms, and supports the use of effective anti-thrombotic therapy.
    keywords: acute; covid-19; infection; therapy
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        item: #4636 of 7819
          id: cord-313355-166b6fep
      author: Zhang, Xiao-Jing
       title: In-hospital Use of Statins is Associated with a Reduced Risk of Mortality among Individuals with COVID-19
        date: 2020-06-24
       words: 8470
      flesch: 38
     summary: The IL-6 in the statin group showed a lower level at admission and had a less increase than that of non-statin group in the entire duration of follow-up ( Figure 3B) . For the mixed Cox analysis, the statin versus non-statin group ratio was paired at 1:4.
    keywords: arb; covid-19; cox; disease; group; increase; individuals; model; statin; table; time; treatment
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        item: #4637 of 7819
          id: cord-313356-ninzeazy
      author: Fiorillo, Luca
       title: COVID-19 Surface Persistence: A Recent Data Summary and Its Importance for Medical and Dental Settings
        date: 2020-04-30
       words: 3808
      flesch: 47
     summary: Concerning the persistence of the virus on different surfaces, and in particular on metals containing copper, these findings are interesting and could lead to the development of new surfaces with viricidal or bactericidal properties. [26] , aerosol and surface virus transmission is plausible, since it can remain viable and infectious for hours or days.
    keywords: bias; coronavirus; covid-19; days; persistence; sars; surfaces
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        item: #4638 of 7819
          id: cord-313382-prxc0lue
      author: Hossein Norooznezhad, Amir
       title: Empiric Antibiotics in Management of Inpatient Pregnant Women Infected with Coronavirus Disease 2019 (COVID-19): Focusing on Inflammation and Preterm Labor
        date: 2020-09-12
       words: 870
      flesch: 32
     summary: However, we have highlighted that the use of antibiotics in the absence of bacterial infection might result in the release of pro-inflammatory cytokine and therefore, an inflammatory storm. During this endotoxemia, the activation of toll-like receptors (TLRs) cause the release/expression of pro-inflammatory cytokines (such as interleukin 1β (IL-1β), IL-6, and tumor necrosis factor α (TNF-α)), chemokines, prostaglandins, and proteases which are involved in preterm labor.
    keywords: covid-19; preterm
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        item: #4639 of 7819
          id: cord-313386-t2p9txlt
      author: Naito, Yuji
       title: Association between selective IgA deficiency and COVID-19
        date: 2020-08-21
       words: 1695
      flesch: 43
     summary: Table 1 presents the number of COVID-19 infections and deaths, populations, and frequencies of selective IgA deficiency in 19 countries. Another important finding in this study was a strong positive correlation between the frequency of selective IgA deficiency and the prevalence of COVID-19 infection per population.
    keywords: covid-19; deficiency; iga; number
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        item: #4640 of 7819
          id: cord-313387-xwb0iphy
      author: Meleo-Erwin, Zoë
       title: Online Support Information for Students with Disabilities in Colleges and Universities during the COVID-19 Pandemic
        date: 2020-10-08
       words: 2649
      flesch: 41
     summary: It is our recommendation that clear links to remote instruction resources and counseling services be placed in the disability/accessibility pages of all institutions of higher education. The majority of institutions did not feature ways to make a counseling appointment or remote instruction resources on disability/accessibility pages •
    keywords: accessibility; college; covid-19; disability; resources; students
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        item: #4641 of 7819
          id: cord-313390-zeo0ud75
      author: Masiero, Stefano
       title: Health resort medicine can be a suitable setting to recover disabilities in patients tested negative for COVID-19 discharged from hospital? A challenge for the future
        date: 2020-06-05
       words: 1436
      flesch: 26
     summary: key: cord-313390-zeo0ud75 authors: Masiero, Stefano; Maccarone, Maria Chiara; Agostini, Francesco title: Health resort medicine can be a suitable setting to recover disabilities in patients tested negative for COVID-19 discharged from hospital? Hence, our proposal for an innovative post-hospitalization rehabilitative treatment, taking advantage of health resort medicine as suitable setting to take care of discharged subjects tested negative for COVID-19.
    keywords: covid-19; health; patients
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        item: #4642 of 7819
          id: cord-313392-a5ynzx70
      author: Liu, Ze-Ming
       title: Association of procalcitonin levels with the progression and prognosis of hospitalized patients with COVID-19
        date: 2020-09-09
       words: 3690
      flesch: 47
     summary: Compared with inpatients with normal PCT levels, inpatients with elevated PCT levels had a higher risk for overall mortality and critically severe disease. Inpatients with elevated PCT levels had a higher risk of overall mortality than those with normal PCT levels.
    keywords: covid-19; disease; elevated; group; normal; patients; pct; score
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        item: #4643 of 7819
          id: cord-313402-f3indt3b
      author: Hong, X.-w.
       title: Analysis of early renal injury in COVID-19 and diagnostic value of multi-index combined detection
        date: 2020-03-10
       words: 2546
      flesch: 53
     summary: title: Analysis of early renal injury in COVID-19 and diagnostic value of multi-index combined detection date: 2020-03-10 journal: nan DOI: 10.1101/2020.03.07.20032599 sha: doc_id: 313402 cord_uid: f3indt3b Objectives The aim of the study was to analyze the incidence of COVID-19 with early renal injury, and to explore the value of multi-index combined detection in diagnosis of early renal injury in COVID-19. Primary and secondary outcome measures The primary outcome was to evaluate the incidence of early renal injury in COVID-19.
    keywords: covid-19; injury; medrxiv; patients; preprint
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        item: #4644 of 7819
          id: cord-313415-5qrpucr4
      author: Lai, Rongtao
       title: Sentinel surveillance strategies for early detection of coronavirus disease in fever clinics: experience from China
        date: 2020-08-25
       words: 1904
      flesch: 44
     summary: Therefore, patients with a normal body temperature (oral temperature <37.3°C) but with respiratory symptoms and underlying disease; as well as those with an epidemiological history, including a history of travel to epidemic areas and contact with COVID-19 patients are recommended to visit fever clinics. To efficiently and effectively control the epidemic and to minimise its negative economic impact, rapid screening and immediate isolation of suspected COVID-19 cases in fever clinics was important.
    keywords: clinics; covid-19; fever; patients
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        item: #4645 of 7819
          id: cord-313427-6y4zvrmn
      author: Mani, Nandita S
       title: Prevalence of COVID-19 Infection and Outcomes Among Symptomatic Healthcare Workers in Seattle, Washington
        date: 2020-06-16
       words: 3434
      flesch: 48
     summary: We established two high-throughput employee testing centers in Seattle, Washington with drive-through and walk-through options for symptomatic employees in the University of Washington Medicine system and its affiliated organizations. Using data from these testing centers, we report the prevalence of SARS-CoV-2 infection among symptomatic employees and describe the clinical characteristics and outcomes among employees with COVID-19.
    keywords: cov-2; covid-19; employees; hcws; healthcare; infection; sars; testing
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        item: #4646 of 7819
          id: cord-313468-lloh1b0y
      author: Fernández‐Aranda, Fernando
       title: COVID Isolation Eating Scale (CIES): Analysis of the impact of confinement in eating disorders and obesity—A collaborative international study
        date: 2020-09-20
       words: 4656
      flesch: 32
     summary: The fear of COVID-19 scale: Development and initial validation Diagnostic and statistical manual of mental disorders COVID-19 and eating disorders during confinement: Analysis of factors associated with resilience and aggravation of symptoms Structural equation modelling: Adjudging model fit Intolerance of uncertainty in eating disorders: A systematic review and meta-analysis The psychological impact of the COVID-19 epidemic on college students in China Development and initial validation of the COVID-19 anxiety scale Identity statuses in prebariatric patients with obesity: Associations with eating disorder symptoms, psychological complaints, and coping behaviour? Exploring the ways in which COVID-19 and lockdown has affected the lives of adult patients with anorexia nervosa and their carers Statistical power for the behavioral sciences Addiction psychiatry and COVID-19-impact on patients and service provision Eating disorders during the COVID-19 pandemic and quarantine: An overview of risks and recommendations for treatment and early intervention Coronavirus disease 2019 (COVID-19) and obesity. Factors F1, F2, F3 and F4 were also developed to allow for assessment prior and following COVID-19 confinement.
    keywords: changes; cies; confinement; covid-19; eating; et al; health; impact; obesity; patients; study
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        item: #4647 of 7819
          id: cord-313480-268xf8i9
      author: Ransing, Ramdas
       title: Infectious Disease Outbreak Related Stigma and Discrimination during the COVID-19 Pandemic: Drivers, Facilitators, Manifestations, and Outcomes across the World
        date: 2020-07-27
       words: 1610
      flesch: 30
     summary: However, certain groups of people across the world are being targeted by COVID-19 related stigma (COS) and discrimination, what constitutes a growing concern(Bagcchi, 2020). Learning from HIV Research Mental Health Interventions during the COVID-19 Pandemic: A Conceptual Framework by Early Career Psychiatrists Can COVID-19 related mental health issues be measured?
    keywords: cos; covid-19; health; people; stigma
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        item: #4648 of 7819
          id: cord-313489-i969aqn9
      author: Galbadage, Thushara
       title: Does COVID-19 Spread Through Droplets Alone?
        date: 2020-04-24
       words: 2345
      flesch: 43
     summary: World Health Organization (2020) Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship Grand Princess Updates SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS) Stability of SARS coronavirus in human specimens and environment and its sensitivity to heating and U.V. irradiation Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1 Human influenza resulting from aerosol inhalation An outbreak of influenza aboard a commercial airliner Exhaled droplets due to talking and coughing Violent expiratory events: on coughing and sneezing Transmission-Based Precautions Review of Scientific Data Regarding Transmission of Infectious Agents in Healthcare Settings We acknowledge research students, Joseph Awada and Danny Ramirez Jr. for their discussions on this research topic. This raises questions of whether a full scientific understanding of disease transmission modes has yet to be attained, and thus whether there are more effective ways to prevent its spread.
    keywords: covid-19; droplets; sars; spread; transmission
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        item: #4649 of 7819
          id: cord-313494-a4pms2ub
      author: Sampedro, Ana Diez
       title: COVID-19 and Advanced Practice Registered Nurses (APRNs): Frontline update #1
        date: 2020-06-18
       words: 3759
      flesch: 39
     summary: Additionally, there is emerging evidence from the frontline that nurses and other healthcare workers are experiencing significant emotional distress as a result of providing direct patient care during this pandemic. Current physician shortages have exacerbated the need for APRNs to fill vital patient care roles as hospitals across the United States (U.S.) are inundated with sick patients.
    keywords: aprns; care; coronavirus; covid-19; disease; health; pandemic; patients; practice; use
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        item: #4650 of 7819
          id: cord-313503-wvgwf9n3
      author: D’Amico, Randy S.
       title: Neurosurgical/Head and Neck drape to Prevent Aerosolization of COVID-19 - The Lenox Hill Hospital/Northwell Health solution.
        date: 2020-07-23
       words: 1105
      flesch: 40
     summary: The COVID-19 aerosolization prevention drape may limit intraoperative dispersal of COVID-19 particles and add an additional layer of protection against the spread of the virus. Guidelines from the Difficult Airway Society, the Association of Anaesthetists the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetists Clear plastic drapes may be effective at limiting aerosolization and droplet spray during extubation: implications for COVID-19 COVID-19 and the
    keywords: covid-19; drape; extubation; procedures
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        item: #4651 of 7819
          id: cord-313518-8a6y1qsf
      author: Abdul-Baki, Mohammad-Nasan
       title: The substantial awareness role of web-based and social media platforms in developing countries during a pandemic scenario: the example of COVID-19
        date: 2020-06-03
       words: 805
      flesch: 40
     summary: key: cord-313518-8a6y1qsf authors: Abdul-Baki, Mohammad-Nasan; Dhemesh, Yaseen; Alasadi, Lugien; Alsuliman, Tamim title: The substantial awareness role of web-based and social media platforms in developing countries during a pandemic scenario: the example of COVID-19 date: 2020-06-03 journal: J Public Health (Oxf) DOI: 10.1093/pubmed/fdaa075 sha: doc_id: 313518 cord_uid: 8a6y1qsf BACKGROUND: During the outbreak of coronavirus COVID-19, social media platforms have shown effectiveness in information dissemination. Today, social media platforms have become a major source of information.
    keywords: covid-19; health
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        item: #4652 of 7819
          id: cord-313528-rp15vi1o
      author: Wallace, Douglas W.
       title: An adapted emergency department triage algorithm for the COVID‐19 pandemic
        date: 2020-08-10
       words: 2117
      flesch: 35
     summary: Government of Canada Respiratory care committee of Chinese Thoracic S. Expert consensus on preventing nosocomial transmission during respiratory care for critically ill patients infected by 2019 novel coronavirus pneumonia Expert recommendations for tracheal intubation in critically ill patients with novel coronavirus disease 2019 Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient Management of Patients with Confirmed 2019-nCoV SARS-Co-V-2 viral load in upper respiratory specimens of infected patients 1-Minute Sit-to-Stand Test: systematic review of procedures, performance, and clinimetric properties Step oximetry test: a validation study Association between hypoxemia and mortality in patients with COVID-19 Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore Chinese Clinical Guidance for COVID-19 Pneumonia Diagnosis and Treatment. 1, 2 Widespread community transmission is occurring in the United States (US) and health systems around the world continue to face challenges in the management of COVID-19 patients.
    keywords: algorithm; care; coronavirus; covid-19; pandemic; patients; triage
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        item: #4653 of 7819
          id: cord-313537-920tgv1j
      author: Carbonell, Ana Piera
       title: Covid-19 y tromboprofilaxis: recomendaciones para nuestra práctica clínica en atención primaria
        date: 2020-09-18
       words: 2642
      flesch: 30
     summary: La interleuquina-6 (IL-6), entre otras interleuquinas, desempeña un papel importante en la red de mediadores inflamatorios y puede causar trastornos de la coagulación a través de diversas vías, como la estimulación hepática para la síntesis de trombopoyetina y fibrinógeno, aumento de la expresión del factor de crecimiento endotelial vascular, expresión de los factores tisulares de los monocitos y la activación del sistema de coagulación extrínseco. 2 La excesiva activación del sistema inmune causa una tormenta de citoquinas y ocasiona daño del sistema microvascular, activando el sistema de coagulación e inhibiendo el de la fibrinólisis.
    keywords: con; cov-2; covid-19; del; enfermedad; los; pacientes; para; por; que; riesgo; sars; trombosis; una
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        item: #4654 of 7819
          id: cord-313543-ad3c0hve
      author: Amram, Ofer
       title: Development of a vulnerability index for diagnosis with the novel coronavirus, COVID-19, in Washington State, USA
        date: 2020-06-26
       words: 1545
      flesch: 42
     summary: The outcome was COVID-19 diagnosis rates. Unadjusted and adjusted multilevel modeling were performed to examine factors associated with COVID-19 diagnosis rates.
    keywords: covid-19; health; index; vulnerability
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        item: #4655 of 7819
          id: cord-313659-jutdl9qu
      author: Mahdavinia, Mahboobeh
       title: Reply to Does asthma affect outcomes of patients with COVID-19 infections?
        date: 2020-09-28
       words: 774
      flesch: 44
     summary: However, as a chronic lung disease prone to viral-induced exacerbation, this might place those 42 with severe COVID-19 at risk for a longer duration of pulmonary inflammation.(2, 5) Furthermore, an 43 allergic background and differential expression of ACE2 and TMPRSS2 may dampen the strong 44 inflammatory response to SARS-CoV-2 in patients with allergic asthma patients, leading to the lack of 45 increased severity reported in patients with non-allergic asthma. (2) The impact of COVID-19 on asthma patients 25 and their COVID-19 outcome has been a matter of several investigations in the past months.
    keywords: asthma; covid-19
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        item: #4656 of 7819
          id: cord-313682-t3zhqrs9
      author: Zhang, Xiaomeng
       title: Safe and effective management of tracheostomy in COVID‐19 patients
        date: 2020-05-19
       words: 2896
      flesch: 39
     summary: They are helpful to rescue severe patients, and at the same time, to protect health care workers from the threat of coronavirus infection. [4] [5] In COVID-19 patients with long-term endotracheal intubation and mechanical ventilation, tracheotomy may be considered.
    keywords: care; covid-19; intubation; patients; sars; tracheostomy
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        item: #4657 of 7819
          id: cord-313684-61hkogdh
      author: Samaddar, Arghadip
       title: Pathophysiology and Potential Therapeutic Candidates for COVID-19: A Poorly Understood Arena
        date: 2020-09-17
       words: 11716
      flesch: 34
     summary: There are currently four ongoing clinical trials of umifenovir for COVID-19 treatment: one in comparison with the basic treatment 6 , and the other three comparing the effects in combination with oseltamivir 7 , lopinavir/ ritonavir 8 , and carrimycin. Currently, there are no clinically proven antiviral drugs or biologics for the treatment of COVID-19 patients.
    keywords: acute; antiviral; cells; combination; coronavirus; cov-2; covid-19; covid-19 patients; disease; et al; host; immune; infection; mers; patients; protein; receptors; response; rna; sars; therapy; treatment; trial; viral; virus
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        item: #4658 of 7819
          id: cord-313700-enivzp1f
      author: Lio, Chon Fu
       title: The common personal behavior and preventive measures among 42 uninfected travelers from the Hubei province, China during COVID-19 outbreak: a cross-sectional survey in Macao SAR, China
        date: 2020-06-19
       words: 3110
      flesch: 42
     summary: Good personal hygiene and adequate preventive measures such as less gathering, frequent handwashing, in addition to wearing a mask outdoor, were common grounds among 42 uninfected participants during the stay in Hubei province under COVID-19 outbreak. key: cord-313700-enivzp1f authors: Lio, Chon Fu; Cheong, Hou Hon; Lei, Chin Ion; Lo, Iek Long; Yao, Lan; Lam, Chong; Leong, Iek Hou title: The common personal behavior and preventive measures among 42 uninfected travelers from the Hubei province, China during COVID-19 outbreak: a cross-sectional survey in Macao SAR, China date: 2020-06-19 journal: PeerJ DOI: 10.7717/peerj.9428 sha: doc_id: 313700 cord_uid: enivzp1f BACKGROUND:
    keywords: china; covid-19; health; hubei; macao; measures; province; wuhan
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        item: #4659 of 7819
          id: cord-313713-70ykst44
      author: Pratap Singh, Ravi
       title: Internet of Medical Things (IoMT) for orthopaedic in COVID-19 pandemic: Roles, challenges, and applications
        date: 2020-05-15
       words: 2438
      flesch: 39
     summary: The remembering feature devices for the aged persons to keep them reminding about various acts like medication, medicine timings, sleeping level monitoring, etc. are some of the specially developed features from IoMT services for the older patients [31] This comprehensive review proposes the possible means of offering medical care to the orthopaedic patients through IoMT approach, during COVID-19 pandemic.
    keywords: covid-19; internet; iomt; orthopaedic; patients; services; things
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        item: #4660 of 7819
          id: cord-313716-pw0odm88
      author: Moccia, Lorenzo
       title: Affective temperament, attachment style, and the psychological impact of the COVID-19 outbreak: an early report on the Italian general population
        date: 2020-04-20
       words: 2839
      flesch: 30
     summary: To fit our aims, we subdivided our sample into three groups according to K10 cutoffs: 1) subjects without likelihood of psychological distress, 2) subjects with likelihood of mild psychological distress, and 3) subjects with likelihood of moderateto-severe psychological distress. In our sample (n=500), 62% of the individuals reported no likelihood of psychological distress, whereas 19.4% and 18.6% displayed mild and moderate-to-severe likelihood.
    keywords: attachment; covid-19; distress; outbreak; temperament
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        item: #4661 of 7819
          id: cord-313728-08kwkbmd
      author: Binda, Barbara
       title: Follow-up and Management of Kidney Transplant Recipients During the COVID-19 Lockdown: the experience of an Italian Transplant Center, Including Two Cases of COVID-19 Pneumonia
        date: 2020-06-28
       words: 3214
      flesch: 34
     summary: On April 29 the Italian Medicines Agency states that, in this emergency phase, the use of hydroxychloroquine can be considered in COVID-19 patients of any severity, evaluating the risk/benefit ratio in each individual case. A recent retrospective cohort study in COVID-19 patients showed that early, low-dose, short-term administration of methylprednisolone was associated with better clinical outcomes in patients with severe COVID-19 pneumonia, and should be considered before the occurrence of acute respiratory distress syndrome [17] .
    keywords: covid-19; disease; infection; kidney; lockdown; patients; recipients; sars; transplant
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        item: #4662 of 7819
          id: cord-313785-8tipkksu
      author: d'Ettorre, Gabriella
       title: Challenges in the Management of SARS-CoV2 Infection: The Role of Oral Bacteriotherapy as Complementary Therapeutic Strategy to Avoid the Progression of COVID-19
        date: 2020-07-07
       words: 3790
      flesch: 35
     summary: The WHO, CDC, and FDA have not taken a position on the use of Tocilizumab in COVID-19, even though China's National Health Commission recommends it for use in COVID-19 patients but only if elevated IL-6 levels are present (15) . The collection of clinical data, examination, and nursing of COVID-19 patients is challenging for the risk of virus transmission.
    keywords: bacteriotherapy; covid-19; data; group; gut; infection; lung; oral; oxygen; patients; virus
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        item: #4663 of 7819
          id: cord-313829-pjscmen8
      author: Caballero, A.E.
       title: COVID-19 in people living with diabetes: An international consensus
        date: 2020-07-06
       words: 4359
      flesch: 45
     summary: A statement from the Diabetes in COVID-19: prevalence, pathophysiology, prognosis and practical considerations Predicting mortality due to SARS-CoV-2: a mechanistic score relating obesity and diabetes to COVID-19 outcomes in Diabetes and COVID-19: more than the sum of two morbidities Diabetic patients with COVID-19 infection are at higher risk of ICU admission and poor short-term outcome Covid-19: The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China Expert recommendations for diabetes management in primary care during the COVID-19 pandemic Guidance on diabetes management in the elderly during the COVID-19 pandemic Recommendations on insulin treatment in diabetes patients affected with COVID-19 COVID-19 weekly surveillance report: data for the week of 8 -14 World Health Organization.
    keywords: care; covid-19; diabetes; glucose; hyperglycemia; insulin; patients; people; risk
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        item: #4664 of 7819
          id: cord-313836-mcm0xmzw
      author: Di Micco, Pierpaolo
       title: Venous Thromboembolism and Its Association with COVID-19: Still an Open Debate
        date: 2020-09-27
       words: 1097
      flesch: 20
     summary: The molecular biology of coronaviruses Recent insights into emerging coronaviruses SARS to novel coronavirus: Old lessons and new lessons Covid-19 has killed more people than SARS and MERS combined, despite lower case fatality rate Acute Pulmonary Embolism and COVID-19 Clotting Factors in COVID-19: Epidemiological Association and Prognostic Values in Different Clinical Presentations in an Italian Cohort Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Autopsy Findings and Venous Thromboembolism in Patients with COVID-19 Empirical systemic anticoagulation is associated with decreased venous thromboembolism in critically ill influenza A H1N1 acute respiratory distress syndrome patients COVID-19 coagulopathy in Caucasian patients COVID-19-Related Severe Hypercoagulability in Patients Admitted to Intensive Care Unit for Acute Respiratory Failure Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Clinical impact of pre-admission antithrombotic therapy in hospitalized patients with COVID-19: A multicenter observational study Is thromboprophylaxis with high-dose enoxaparin really necessary for COVID-19 patients? The prevalence of PE in COVID-19 patients ranges from 15% to 40%; this large difference across clinical studies may be due tothe size and heterogeneity of sample populations, presenting significant differences in clinical characteristics, pre-admission pharmacological treatments and anticoagulation regimens used for VTE prophylaxis during the hospitalization [14]
    keywords: covid-19; patients; vte
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        item: #4665 of 7819
          id: cord-313887-8sabsrgy
      author: Quandt, Sara A.
       title: COVID-19 Pandemic among Latinx Farmworker and Nonfarmworker Families in North Carolina: Knowledge, Risk Perceptions, and Preventive Behaviors
        date: 2020-08-10
       words: 7455
      flesch: 48
     summary: There was virtually no mask wearing reported by farmworker family respondents, and only some use of masks reported by nonfarmworker respondents. In all cases, we will compare farmworker families and families with no worker engaged in farm work.
    keywords: behaviors; covid-19; families; farmworker; health; knowledge; masks; nonfarmworker; respondents; sample; study; workers
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        item: #4666 of 7819
          id: cord-313894-stgx36h5
      author: Ürün, Yüksel
       title: Survey of the Impact of COVID-19 on Oncologists’ Decision Making in Cancer
        date: 2020-08-05
       words: 4287
      flesch: 40
     summary: The impact of COVID-19 outbreak on uro-oncological practice across Europe: Which burden of activity are we facing ahead? Risks from deferring treatment for genitourinary cancers: A collaborative review to aid triage and management during the COVID-19 pandemic Case fatality rate of cancer patients with COVID-19 in a New York hospital system The experience of treating patients with cancer during the COVID-19 pandemic in China TERAVOLT (Thoracic cancERs international coVid 19 cOLlaboraTion): First results of a global collaboration to address the impact of COVID-19 in patients with thoracic malignancies Managing patients with cancer during the COVID-19 pandemic: Frontline experience from Wuhan Patients with cancer appear more vulnerable to SARS-COV-2: A multicenter study during the COVID-19 outbreak Clinical characteristics of COVID-19-infected cancer patients: A retrospective case study in three hospitals within Wuhan, China Outcome of cancer patients infected with COVID-19, including toxicity of cancer treatments SARS-CoV-2 transmission in patients with cancer at a tertiary care hospital in Wuhan, China Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Caring for patients with cancer in the COVID-19 era European Association of Urology Guidelines Office Rapid Reaction Group: An organisation-wide collaborative effort to adapt the European Association of Urology Guidelines recommendations to the coronavirus disease 2019 era Advice regarding systemic therapy in patients with urological cancers during the COVID-19 pandemic Considerations in the triage of urologic surgeries during the COVID-19 pandemic The shifting landscape of genitourinary oncology during the COVID-19 pandemic and how Italian oncologists reacted: Results from a national survey How to guarantee the best of care to patients with cancer during the COVID-19 epidemic: The Italian experience Oncology practice during the COVID-19 pandemic The COVID-19 and Cancer Consortium (CCC19): A collaborative effort to understand the effects of COVID-19 on patients with cancer Impact of the COVID-19 pandemic on the symptomatic diagnosis of cancer: The view from primary care Lessons from a pooled meta-analysis Androgen-deprivation therapies for prostate cancer and risk of infection by SARS-CoV-2: A population-based study (N = 4532) Impact of anti-androgenic therapies on COVID-19: An observational study in male population from a COVID-19 regional centre of Lombardy (Italy) Treatment of the immune-related adverse effects of immune checkpoint inhibitors: A review Determinants of severity in cancer patients with COVID-19 illness Pathogenic T cells and inflammatory monocytes incite inflammatory storm in severe COVID-19 patients Ethics and resource scarcity: ASCO recommendations for the oncology community during the COVID19 pandemic Crowdsourcing a crisis response for COVID-19 in oncology
    keywords: cancer; covid-19; oncologists; pandemic; participants; patients; risk; survey; treatment
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        item: #4667 of 7819
          id: cord-313916-i9af6rgx
      author: Kuhn, Andrew W.
       title: To “Heed the Call” Amidst the COVID-19 Pandemic: Perspectives From 4 Incoming Orthopaedic Surgery Interns
        date: 2020-06-09
       words: 1915
      flesch: 45
     summary: Important Guidance for Medical Students on Clinical Rotations during the Coronavirus (COVID-19) Outbreak The Role of medical students during the COVID-19 pandemic Medical student mobilization during a crisis: lessons from a COVID-19 medical student response team A Review of state guidelines for elective orthopaedic procedures during the COVID-19 outbreak Guidelines for ambulatory surgery centers for the care of surgically necessary/time-sensitive orthopaedic cases during the COVID-19 pandemic Preparing to perform trauma and orthopaedic surgery on patients with COVID-19 What's important: redeployment of the orthopaedic surgeon during the COVID-19 pandemic: perspectives from the trenches Current trends in orthopaedic surgery residency applications and Match Rates Graduation Questionnaire Not the last word: ending the residency application arms racestarting with the USMLE Matching in orthopaedic surgery Critical assessment of the contemporary orthopaedic surgery residency application process key: cord-313916-i9af6rgx authors: Kuhn, Andrew W.; Coxe, Francesca R.; Kunze, Kyle N.; Bernstein, David N. title: To “Heed the Call” Amidst the COVID-19 Pandemic: Perspectives From 4 Incoming Orthopaedic Surgery Interns date: 2020-06-09 journal: JB JS Open Access DOI: 10.2106/jbjs.oa.20.00063 sha: doc_id: 313916 cord_uid: i9af6rgx As incoming orthopaedic surgery interns, we enter the workforce amidst a global pandemic—a pivotal moment in history.
    keywords: covid-19; medical; orthopaedic; pandemic
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        item: #4668 of 7819
          id: cord-313937-uxz9uedr
      author: Qiu, Jian-Yin
       title: Mental Wellness system for COVID-19
        date: 2020-04-13
       words: 673
      flesch: 30
     summary: We are setting up a comprehensive system including population level monitoring of mental states, online emergency psychological intervention based on artificial intelligence, community based scientific dissemination and social bond enhancement, virtual reality and neuromodulation based intervention, and human resources training for emergency psychological interventions. Scientific knowledge relate to COVID-19 (e.g. the infection mechanism, the population transmission model, the proper prevention method, and the treatment approaches) are provided as online content and social media based dissemination, as well as through community management system to the public population.
    keywords: community; covid-19; population
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        item: #4669 of 7819
          id: cord-313947-2u77y1gx
      author: Gelardi, Matteo
       title: COVID-19: what happened to all of the otolaryngology emergencies?
        date: 2020-05-18
       words: 877
      flesch: 40
     summary: Table 1 shows data regarding the number of emergency department consultations by diagnosis in the 30 days preceding (from February 8th to March 8th, 2020) and 30 days following (from March 9th to April 9th, 2020) the onset of the COVID-19 outbreak at the two main tertiary referral centers in the Puglia region, as well as the percentage reduction for each diagnosis. One aspect is that access to emergency care in Otolaryngology (ORL) patients has already changed in the month following the onset of the COVID-19 outbreak, and, seemingly, many non-COVID illnesses have been disappearing.
    keywords: care; emergency; patients
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        item: #4670 of 7819
          id: cord-313976-q5j5kr1v
      author: Alaarag, Ahmed
       title: Clinical and angiographic characteristics of patients with STEMI and confirmed diagnosis of COVID-19: an experience of Tanta University Hospital
        date: 2020-10-06
       words: 3012
      flesch: 45
     summary: [21] in a study performed in 4 countries in COVID-19 patients with STEMI primary PCI was the treatment strategy in 24% of patients, while fibrinolytic therapy was the treatment in 76% of patients. key: cord-313976-q5j5kr1v authors: Alaarag, Ahmed; Hassan, Timoor; Samir, Sameh; Naseem, Mohamed title: Clinical and angiographic characteristics of patients with STEMI and confirmed diagnosis of COVID-19: an experience of Tanta University Hospital date: 2020-10-06 journal: Egypt Heart J DOI: 10.1186/s43044-020-00103-y sha: doc_id: 313976 cord_uid: q5j5kr1v BACKGROUND: Patients with established cardiovascular diseases have a poor prognosis when affected by the coronavirus disease 2019 (COVID-19).
    keywords: burden; covid-19; myocardial; patients; stemi; study; thrombus
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        item: #4671 of 7819
          id: cord-313980-jutof78v
      author: van de Veerdonk, F. L.
       title: A systems approach to inflammation identifies therapeutic targets in SARS-CoV-2 infection
        date: 2020-05-24
       words: 4687
      flesch: 45
     summary: Unsupervised clustering analysis of the PEA proteins that significantly differ between ICU and non ICU, C-reactive protein (CRP), D-dimer, ferritin, C3a, C3c and TCC, revealed that ICU patients cluster separately from non ICU patients, but that within these clusters no significantly different profiles could be identified ( Figure 3A ). Although circulating ferritin concentrations were also increased in ICU patients as compared to non ICU COVID-19 patients, no statistically significant differences were observed (1470 µg/l
    keywords: copyright; covid-19; holder; icu; license; medrxiv; medrxiv preprint; patients; perpetuity; preprint; version
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        item: #4672 of 7819
          id: cord-313984-7wvfnag1
      author: Remy, Kenneth E
       title: Immunotherapies for COVID-19: lessons learned from sepsis
        date: 2020-04-28
       words: 2175
      flesch: 31
     summary: T cell-induced cytokine release syndrome FDA Approval Summary: Tocilizumab for treatment of chimeric antigen receptor T cell-induced severe or lifethreatening cytokine release syndrome Cytokine storm and sepsis disease pathogenesis Failure of treatments based on the cytokine storm theory of sepsis: time for a novel approach Tocilizumab treatment in COVID-19: a single center experience The cytokine release syndrome (CRS) of severe COVID-19 and interleukin-6 receptor (IL-6R) antagonist tocilizumab may be the key to reduce the mortality IL-6 in inflammation, immunity, and disease Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Study of the lymphocyte change between COVID-19 and non-COVID-19 pneumonia cases suggesting other factors besides uncontrolled inflammation contributed to multi-organ injury Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients Functional exhaustion of antiviral lymphocytes in COVID-19 patients The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): the perspectives of clinical immunologists from China Immunosuppression for hyperinflammation in COVID-19: a double-edged sword? First, better methods are needed to assess the functional status of immune cells in patients with COVID-19.
    keywords: concentrations; covid-19; cytokine; il-6; patients; sepsis
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        item: #4673 of 7819
          id: cord-313989-bc7q8swu
      author: Nicholls, Stephen J.
       title: Optimising Secondary Prevention and Cardiac Rehabilitation for Atherosclerotic Cardiovascular Disease During the COVID-19 Pandemic: A Position Statement from the Cardiac Society of Australia and New Zealand (CSANZ) #
        date: 2020-04-30
       words: 3648
      flesch: 30
     summary: International guidelines for the care of CVD patients during the COVID-19 pandemic includes advice to address CVD risk factors and promote recovery [12] , and cardiac rehabilitation programs have well-established efficacy for supporting patients with lifestyle change [13] . Perceived or actual loss commonly results in depression and is more prevalent in CVD patients [31] .
    keywords: cardiac; cardiovascular; care; covid-19; cvd; health; heart; patients; prevention; risk
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        item: #4674 of 7819
          id: cord-313992-ogdqq3dl
      author: Kortuem, S. O.
       title: Corona-Independent Excess Mortality Due to Reduced Use of Emergency Medical Care in the Corona Pandemic: A Population-Based Observational Study
        date: 2020-10-28
       words: 4140
      flesch: 41
     summary: A significant decrease in the number of cases of emergency medical care during the first phase of the Corona pandemic has been reported from various regions of the world. This paper investigates changes in the use of clinical and pre-clinical structures of emergency medical care as well as effects on overall mortality in a rural supply area during the first phase of the corona pandemic (9th to 22nd calendar week 2020).
    keywords: care; covid-19; emergency; number; pandemic; patients; period; preprint
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        item: #4675 of 7819
          id: cord-314002-zm02k9bw
      author: Ayanian, Shant
       title: The association between biomarkers and clinical outcomes in novel coronavirus pneumonia in a US cohort
        date: 2020-07-17
       words: 2653
      flesch: 43
     summary: Of further significance is that our cohort of COVID-19 patients admitted to the hospitalist service revealed that the highest odds of death occurred when the LDH level was greater than 1200 units/l and a D-dimer level was greater than 3 μg/ml. As the care of COVID-19 patients became standardized, more clinicians began checking biomarkers.
    keywords: biomarkers; cohort; covid-19; dimer; disease; patients
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        item: #4676 of 7819
          id: cord-314006-fz1ckclm
      author: Taylor, C. Barr
       title: Digital technology can revolutionize mental health services delivery: The COVID‐19 crisis as a catalyst for change
        date: 2020-05-25
       words: 1878
      flesch: 34
     summary: Despite the benefits of digital mental health service delivery for widespread use, in the United States, state licensing regulations are a major impediment. Although digital therapies are standard practice in many clinics around the world (Titov et al., 2019) and teletherapy has become routine practice in the United States' Veteran's Affairs Health Care system, on the whole, continued attention is needed to sustainably embed digital mental health in routine care.
    keywords: care; covid-19; health; interventions; services
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        item: #4677 of 7819
          id: cord-314013-g091lv0s
      author: Belladonna, Maria Laura
       title: Potential Benefits of Tryptophan Metabolism to the Efficacy of Tocilizumab in COVID-19
        date: 2020-06-19
       words: 2402
      flesch: 27
     summary: Here, we briefly discuss the potentially multiple, synergistic mechanisms whereby tocilizumab might exert therapeutic activity, mostly focusing on the production of tryptophan-derived catabolites that would result from blockade of IL-6 signaling, as contextualized to the cytokine storm occurring in COVID-19 patients. Based on the infection emergence, strict eligible criteria were adopted in most studies for the recruitments of COVID-19 patients.
    keywords: covid-19; ido1; il-6; patients; tcz
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        item: #4678 of 7819
          id: cord-314014-d9jwy5b6
      author: Duan, Hongxia
       title: Impact of the COVID-19 pandemic on mental health in the general Chinese population: Changes, predictors and psychosocial correlates
        date: 2020-08-18
       words: 4181
      flesch: 38
     summary: A systematic review, meta-analysis, and methodologic considerations for advancing the field The behavioral immune system: Implications for social cognition, social interaction, and social influence Age differences in brain activity during emotion processing: Reflections of age-related decline or increased emotion regulation Infectious disease prevalence, not race exposure, predicts both implicit and explicit racial prejudice across the United States Perceived discrimination and health: a meta-analytic review Social support and coping strategies as mediators of adult adjustment following childhood maltreatment Stress and the social brain: behavioural effects and neurobiological mechanisms The association between social relationships and depression: a systematic review Child abuse and neglect, social support, and psychopathology in adulthood: A prospective investigation Moderators and mediators of the stress-aggression relationship: Executive function and state anger Aggression, social stress, and the immune system in humans and animal models Psychological symptoms of ordinary Chinese citizens based on SCL-90 during the level I emergency response to COVID-19 Coping strategies and social support as mediators of consequences in child sexual abuse victims Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (COVID-19) epidemic among the general population in China A longitudinal study on the mental health of general population during the COVID-19 epidemic in China The second aim was to examine whether perceived stress level to the COVID-19 pandemic would predict an increase in hostility and whether coping strategies would play a potential intermediating role in the relationship between stress and hostility.
    keywords: coping; hostility; level; pandemic; stress; support
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        item: #4679 of 7819
          id: cord-314070-8qz23nn4
      author: Gubbi, Sriram
       title: Catecholamine physiology and its implications in patients with COVID-19
        date: 2020-10-28
       words: 5344
      flesch: 24
     summary: key: cord-314070-8qz23nn4 authors: Gubbi, Sriram; Nazari, Matthew A; Taieb, David; Klubo-Gwiezdzinska, Joanna; Pacak, Karel title: Catecholamine physiology and its implications in patients with COVID-19 date: 2020-10-28 journal: Lancet Diabetes Endocrinol DOI: 10.1016/s2213-8587(20)30342-9 sha: doc_id: 314070 cord_uid: 8qz23nn4 PPGL are well studied disease processes in which the effects of catecholamines are easily discernible and therefore their potential biochemical and physiological influences in patients with COVID-19 can be explored.
    keywords: acute; adrenoceptor; catecholamines; covid-19; cytokine; disease; effects; excess; hypertension; patients; ppgl; risk; syndrome
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        item: #4680 of 7819
          id: cord-314081-6y5ibktt
      author: Lorente, Leonardo
       title: Association between red blood cell distribution width and mortality of COVID-19 patients
        date: 2020-11-07
       words: 4266
      flesch: 52
     summary: Prospective and observational study carried out in 8 Intensive Care Units from 6 hospitals of Canary Islands (Spain) including COVID-19 patients. We had previously found that RDW at ICU admission was associated with mortality in brain infarction [22] and in septic patients [23] , but this association in COVID-19 patients has not been reported so far.
    keywords: mortality; patients; rdw; study
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        item: #4681 of 7819
          id: cord-314085-y59a27oy
      author: Nash, David B.
       title: New Normal for Medical Practice Post COVID-19?
        date: 2020-10-01
       words: 441
      flesch: 43
     summary: I hope that, in addition to drawing needed attention to an important population health issue, this supplement leads clinicians, professional organizations, payers, and policy makers to revisit 'business as usual' with an eye toward optimizing health care now and into the future. Already an accepted mode of health care delivery in the United States, there is convincing evidence that telehealth is efficient, effective, and beneficial for specific uses and patient populations.
    keywords: care; vaginitis
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        item: #4682 of 7819
          id: cord-314109-wb45naw2
      author: Maiese, Kenneth
       title: The Mechanistic Target of Rapamycin (mTOR): Novel Considerations as an Antiviral Treatment
        date: 2020-06-17
       words: 4150
      flesch: 29
     summary: Recent work has shown that mTOR pathways in conjunction with AMPK may offer valuable targets to control cell injury, oxidative stress, mitochondrial dysfunction, and the onset of hyperinflammation, a significant disability associated with COVID-19. Yet, important considerations for the development of safe and effective antiviral therapy with mTOR pathways exist.
    keywords: activation; activity; ampk; cell; complex; covid-19; mtor; mtorc1; pathways; protein; virus
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        item: #4683 of 7819
          id: cord-314113-m46j1379
      author: Arias, Jose
       title: COVID-19 effect on herding behaviour in European Capital Markets
        date: 2020-10-01
       words: 1368
      flesch: 50
     summary: Death and contagious infectious diseases: Impact of the COVID-19 virus on stock market returns Coronavirus (COVID-19)-An epidemic or pandemic for financial markets Epidemics and economics: New and resurgent infectious diseases can have far-reaching economic repercussions An examination of herd behavior in equity markets: an international perspective An empirical analysis of herd behavior in global stock markets Following the pied piper: do individual returns herd around the market? Finance Research Letters A cross-country analysis of herd behavior in Europe Herding behavior in Chinese stock markets: An examination of A and B shares Christian Espinosa Méndez: Conceptualization, Methodology, Software, Data curation, Writing-Original draft preparation, Visualization, Investigation, Validation, Writing-Reviewing and Editing.
    keywords: covid-19; herding; january; markets
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        item: #4684 of 7819
          id: cord-314121-ez62fx9p
      author: de Chaisemartin, C.
       title: BCG vaccination in infancy does not protect against COVID-19. Evidence from a natural experiment in Sweden.
        date: 2020-06-23
       words: 2903
      flesch: 52
     summary: key: cord-314121-ez62fx9p authors: de Chaisemartin, C.; de Chaisemartin, L. title: BCG vaccination in infancy does not protect against COVID-19. We used regression discontinuity to assess the effect of BCG vaccination on Covid-19 related outcomes.
    keywords: bcg; covid-19; medrxiv; preprint; vaccination
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        item: #4685 of 7819
          id: cord-314135-udce22id
      author: Geisslinger, Franz
       title: Cancer Patients Have a Higher Risk Regarding COVID-19–and Vice Versa?
        date: 2020-07-06
       words: 6426
      flesch: 40
     summary: UK COVID-19: Consider cytokine storm syndromes and immunosuppression Comorbidity and its impact on 1590 patients with COVID-19 in China: A nationwide analysis Likelihood of survival of coronavirus disease 2019 Virus induced inflammation and cancer development Understanding pathways to death in patients with COVID-19 COVID-19 infection in cancer patients: Early observations and unanswered questions Cancer patients in SARS-CoV-2 infection: A nationwide analysis in China Patients with cancer appear more vulnerable to SARS-COV-2: A multi-center study during the COVID-19 outbreak Analysis of the susceptibility of lung cancer patients to SARS-CoV-2 infection Respiratory Viral Infections in Patients With Cancer or Undergoing Hematopoietic Cell Transplant Varicella-zoster infection in adult cancer patients. International Collaborative Group How we treat patients with lung cancer during the SARS-CoV-2 pandemic: Primum non nocere Von Bergwelt-Baildon, M.S. Cytokine release syndrome Inflammatory mechanisms in the lung Key mechanisms governing resolution of lung inflammation Role of cytokines as a double-edged sword in sepsis Cytokine storm and sepsis disease pathogenesis Into the Eye of the Characteristics of lymphocyte subsets and cytokines in peripheral blood of 123 hospitalized patients with 2019 novel coronavirus pneumonia (NCP) Dysregulation of Immune Response in Patients with COVID-19 in Wuhan Preventing COVID-19-induced pneumonia with anticytokine therapy Rational Use of Tocilizumab in the Treatment of Novel Coronavirus Pneumonia Immunity to viruses Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients ACE2 as therapy for pulmonary arterial hypertension: The good outweighs the bad Angiotensin-Converting Enzyme 2 (ACE2) in Disease Pathogenesis Angiotensin II revisited: New roles in inflammation, immunology and aging The Anti-Inflammatory Potential of ACE2/Angiotensin-(1-7)/Mas Receptor Axis: Evidence from Basic and Clinical Research Angiotensin-Converting Enzyme 2 as a Therapeutic Target for Heart Failure SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: Molecular mechanisms and potential therapeutic target Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury COVID-19, ACE2, and the cardiovascular consequences COVID-19 and the cardiovascular system Differential Downregulation of ACE2 by the Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus and Human Coronavirus NL63 A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury Inflammatory responses and inflammation-associated diseases in organs Inflammation and Cancer: Triggers, Mechanisms, and Consequences Immunological Approaches Towards Cancer and Inflammation: A Cross Talk Inflammation and Lung Cancer: Roles of Reactive Oxygen/Nitrogen Species Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: Relation to the acute lung injury and pathogenesis of SARS † Oncoviruses Can Drive Cancer by Rewiring Signaling Pathways Through Interface Mimicry Inflammation-associated remodelling and fibrosis in the lung-A process and an end point Carcinogenesis on the background of liver fibrosis: Implications for the management of hepatocellular cancer Idiopathic Pulmonary Fibrosis and Lung Cancer: Mechanisms and Molecular Targets Histopathologic Changes and SARS-CoV-2 Immunostaining in the Lung of a Patient With COVID-19 Mechanical Ventilation-associated Lung Fibrosis in Acute Respiratory Distress Syndrome Persistent infection of SARS coronavirus in colonic cells in vitro Severe acute respiratory syndrome coronavirus persistence in Vero cells Persistent Replication of Severe Acute Respiratory Syndrome Coronavirus in Human Tubular Kidney Cells Selects for Adaptive Mutations in the Membrane Protein Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients Human Genital Cancer: Synergism Between Two Virus Infections or Synergism Between a Virus Infection and Initiating Events? Harald zur Hausen-Facts Viral Oncology: Molecular Biology and Pathogenesis Hallmarks of Cancer:
    keywords: ace2; cancer; coronavirus; cov-2; covid-19; disease; infection; inflammation; patients; risk; sars; studies; virus
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        item: #4686 of 7819
          id: cord-314152-wd153s1g
      author: Noor, Farha Musharrat
       title: Prevalence and Associated Risk Factors of Mortality Among COVID-19 Patients: A Meta-Analysis
        date: 2020-09-12
       words: 4770
      flesch: 50
     summary: A study of 302 patients from Italy Reply to COVID-19 in persons with haematological cancers: A focus on myeloid neoplasms and risk factors for mortality Clinical characteristics and prognostic factors in COVID-19 patients aged≥ 80 years Laboratory predictors of death from coronavirus disease 2019 (COVID-19) in the area of Valcamonica, Italy Baseline chronic comorbidity and mortality in laboratory-confirmed COVID-19 cases: Results from the PRECOVID study in Spain COVID-19: clinical course and outcomes of 36 hemodialysis patients in Spain Clinical course and prognostic factors of COVID-19 infection in an elderly hospitalized population Risk factors for mortality and respiratory support in elderly patients hospitalized with COVID-19 in Korea Neurological diseases as mortality predictive factors for patients with COVID-19: A retrospective cohort study Initial gastrointestinal manifestations in patients with SARS-CoV-2 in 112 patients from veracruz (Southeastern Mexico) Predicting mortality due to SARS-CoV-2: A mechanistic score relating obesity and diabetes to COVID-19 outcomes in Mexico Clinical profile of 100 confirmed COVID-19 patients admitted in dhaka medical college hospital Mortality and survival of COVID-19 Identifying Patients at Greatest risk of mortality due to COVID-19: A new England perspective Demographic and clinical features of critically ill patients with COVID-19 in Greece: The burden of diabetes and obesity Epidemiological characteristics of coronavirus disease 2019 (COVID-19) patients in IRAN: A single center study Characteristics, risk factors and outcomes among the first consecutive 1096 patients diagnosed with COVID-19 Characteristics, comorbidities, 30-day outcome and in-hospital mortality of patients hospitalised with COVID-19 in a Swiss area-a retrospective cohort study Performance of pneumonia severity index and CURB-65 in predicting 30-day mortality in patients with COVID-19 Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort Comparison of confirmed COVID-19 with SARS and MERS cases-clinical characteristics, laboratory findings, radiographic signs and outcomes: A systematic review and meta-analysis Coronavirus: Covid-19 has killed more people than SARS and MERS combined, despite lower case fatality rate Age and multimorbidity predict death among COVID-19 patients: results of the SARS-RAS study of the Italian Society of hypertension Outcomes and prognostic factors in 267 patients with severe acute respiratory syndrome in Hong Kong Predictors of mortality in Middle East respiratory syndrome (MERS) Comorbidity and its impact on 1590 patients with covid-19 in China: A nationwide analysis Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: results from a single Italian centre study on tocilizumab versus standard of care This meta-analysis revealed that the mortality rate among COVID-19 patients was highest in the European region and older age, gender, ICU patients, patients with comorbidity had a high risk for case fatality.
    keywords: analysis; covid-19; disease; factors; mortality; patients; risk; studies; study
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        item: #4687 of 7819
          id: cord-314171-431buxxr
      author: Dariya, Begum
       title: Understanding novel COVID-19: its impact on organ failure and risk assessment for diabetic and cancer patients
        date: 2020-05-06
       words: 6905
      flesch: 47
     summary: Earlier research showed that about 6.7% of SARS patients possessed acute kidney injury (AKI), leading to a mortality of almost 91.7% Organizations around the world debated potential therapeutic strategies for treating COVID-19 patients and public health strategies.
    keywords: ace2; angiotensin; cells; clinical; coronavirus; cov-2; covid-19; host; patients; protein; r n; receptor; sars; virus
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        item: #4688 of 7819
          id: cord-314174-7axpgwva
      author: Lang, Min
       title: Operational challenges of a low-dose CT lung cancer screening program during the COVID-19 pandemic
        date: 2020-10-26
       words: 648
      flesch: 42
     summary: The average weekly LCS LDCT volume decreased by 74% 15 from the pre-COVID peak period to the COVID peak period, followed by gradual recovery, 16 reaching 68% of average pre-COVID peak LCS weekly volume by the end of July (week 29; 17 Figure 2A ). Average weekly non-LCS chest CT volume decreased by 29% from the pre-COVID peak period 13 to the COVID peak period and recovered to 92% of pre-COVID peak levels during the post-14 COVID peak period (Figure 2A) .
    keywords: covid; peak
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        item: #4689 of 7819
          id: cord-314188-q8pxpw1f
      author: Bradshaw, Ralph A.
       title: On pandemics, pandemonium, and possibilities…
        date: 2020-05-12
       words: 1302
      flesch: 47
     summary: The possibilities that could emerge after the pandemic has wound down are truly unique-a potential watershed moment for science, sparked by a new focus on science teaching and training, and by investments in basic and applied research (including science policy), that could better prepare governments and the citizenry for existential threats in the future: pandemics, climate change, food production, etc. Continued investments in biomedical research will also continue to yield exciting advances in the treatment of other killers such as cancer, heart disease, and neurodegeneration that, unlike the pandemic, will not have faded away. key: cord-314188-q8pxpw1f authors: Bradshaw, Ralph A.; Stahl, Philip D. title: On pandemics, pandemonium, and possibilities… date: 2020-05-12 journal: FASEB Bioadv DOI: 10.1096/fba.2020-00023 sha: doc_id: 314188 cord_uid: q8pxpw1f nan
    keywords: covid; pandemic; research
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        item: #4690 of 7819
          id: cord-314197-om3pggwa
      author: Altmayer, Stephan
       title: Comparison of the computed tomography findings in COVID-19 and other viral pneumonia in immunocompetent adults: a systematic review and meta-analysis
        date: 2020-06-27
       words: 3883
      flesch: 40
     summary: Other manifestations, such as consolidations, lower lobe predilection, and predominantly peripheral distribution of disease, are often reported in CT studies of patients with COVID-2019 Except for a higher prevalence of peripheral distribution, involvement of upper and middle lobes, COVID-19, and non-COVID viral pneumonia had overlapping chest CT findings.
    keywords: chest; covid-19; findings; non; patients; pneumonia; studies
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        item: #4691 of 7819
          id: cord-314211-tv1nhojk
      author: Eltoukhy, Abdelrahman E. E.
       title: Data Analytics for Predicting COVID-19 Cases in Top Affected Countries: Observations and Recommendations
        date: 2020-09-27
       words: 9263
      flesch: 55
     summary: This study investigates how new COVID-19 cases can be predicted while considering the historical data of COVID-19 cases alongside the external factors that affect the spread of the virus. The unexpected large number of COVID-19 cases has disrupted the healthcare system in many countries and resulted in a shortage of bed spaces in the hospitals.
    keywords: algorithm; countries; covid-19 cases; data; factors; future; network; neural; number; prediction; research; study
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        item: #4692 of 7819
          id: cord-314218-6znw9zcz
      author: Baron, D. M.
       title: Patient blood management during the COVID–19 pandemic: a narrative review
        date: 2020-05-06
       words: 3409
      flesch: 35
     summary: The important role for intravenous iron in perioperative patient blood management in major abdominal surgery: a randomized controlled trial Randomized clinical trial of preoperative oral versus intravenous iron in anaemic patients with colorectal cancer Preoperative management of colorectal cancer-induced iron deficiency anemia in clinical practice: data from a large observational cohort Intravenous iron isomaltoside 1000 (Monofer(R)) reduces postoperative anaemia in preoperatively non-anaemic patients undergoing elective or subacute coronary artery bypass graft, valve replacement or a combination thereof: a randomized doubleblind placebo-controlled clinical trial (the PROTECT trial) Effect of ultra-shortterm treatment of patients with iron deficiency or anaemia undergoing cardiac surgery: a prospective randomised trial Intravenous ferric carboxymaltose versus standard care in the management of postoperative anaemia: a prospective, open-label, randomised controlled trial Effect of intravenous ferric carboxymaltose on hemoglobin response among patients with acute isovolemic anemia following gastrectomy: the FAIRY randomized clinical trial Clinical characteristics of coronavirus disease 2019 in China Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Patient blood management in the intensive care unit Safety and efficacy of erythropoiesis-stimulating agents in critically ill patients admitted to the intensive care unit: a systematic review and meta-analysis Practical guidance for the prevention of thrombosis and management of coagulopathy and disseminated intravascular coagulation of patients infected with COVID-19 Time course of hemoglobin concentrations in nonbleeding intensive care unit patients Interventions to prevent iatrogenic anemia: a Laboratory Medicine Best Practices systematic review Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan Old, older, the oldest: red blood cell storage and the potential harm of using older red blood cell concentrates A consensus redefinition of transfusion-related acute lung injury Prominent changes in blood coagulation of patients with SARS-CoV-2 infection. Early reports have described mild anaemia in COVID-19 patients admitted to the ICU
    keywords: anaemia; blood; clinical; covid-19; iron; management; pandemic; patients; surgery
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        item: #4693 of 7819
          id: cord-314229-9k2dd95b
      author: Spaccaferri, G.
       title: Cas groupés d’infections au nouveau coronavirus (SARS-CoV-2) aux Contamines-Montjoie, Haute-Savoie, janvier–février 2020
        date: 2020-09-30
       words: 1971
      flesch: 58
     summary: Matériels et méthodes Un cas possible était défini comme tout patient présentant des signes cliniques d’infection respiratoire aiguë et ayant un lien avec le cas index ou avec un cas confirmé lié à ce cas index ; un cas confirmé était un cas possible avec un prélèvement positif par RT-PCR à SARS-CoV-2. Introduction Peu de cas de COVID-19 chez des patients infectés par le VIH ont été rapportés dans la littérature.
    keywords: cas; des; les; ont; patients; une; été
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        item: #4694 of 7819
          id: cord-314272-ey2onl0j
      author: Zhang, H.
       title: A Web-based, Mobile Responsive Application to Screen Healthcare Workers for COVID Symptoms: Descriptive Study
        date: 2020-04-22
       words: 4212
      flesch: 45
     summary: We custom developed COVID Pass to meet local requirements for employee symptom attestation. Aggregate descriptive statistics including overall employee attestations by day and site, employee attestations by application method (COVID Pass automatic screening vs. manual screening), employee attestations by time of day, and percentage of employees reporting COVID-19 symptoms Results: We rapidly created the MVP and gradually deployed it across the hospitals in our organization.
    keywords: application; covid; covid-19; data; employees; pass; screening; symptoms; week
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        item: #4695 of 7819
          id: cord-314280-kf2bo06e
      author: Brissot, Eolia
       title: Management of patients with acute leukemia during the COVID-19 outbreak: practical guidelines from the acute leukemia working party of the European Society for Blood and Marrow Transplantation
        date: 2020-06-11
       words: 2159
      flesch: 38
     summary: Moreover, Liang et al. reported that 1% of COVID-19 patients had a history of cancer, higher than that of the overall Chinese population (0.29%), with lung cancer being the most frequently found. Another aspect which may probably be even more relevant in cancer patients is their inability to receive the necessary care in time, under the changed scenario of a viral pandemic management.
    keywords: acute; allo; case; covid-19; leukemia; patients; risk
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        item: #4696 of 7819
          id: cord-314311-xbpb9nfi
      author: Ge, Huipeng
       title: The epidemiology and clinical information about COVID-19
        date: 2020-04-14
       words: 5298
      flesch: 51
     summary: Isolating virus from urine of the patient with novel coronavirus pneumonia Pattern of early human-to-human transmission of Wuhan Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: a datadriven analysis in the early phase of the outbreak Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study The reproductive number of COVID-19 is higher compared to SARS coronavirus An updated estimation of the risk of transmission of the novel coronavirus (2019-nCov) Middle East respiratory syndrome MERS coronavirus outbreak: implications for emerging viral infections MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2 First case of 2019 novel coronavirus in the United States CT imaging features of 2019 novel coronavirus (2019-nCoV). However, patients with SARS and MERS have more gastrointestinal involvement (about one-third) than COVID-19 patients [55] .
    keywords: china; clinical; coronavirus; cov-2; covid-19; disease; human; ncov; novel; patients; pneumonia; sars; wuhan
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        item: #4697 of 7819
          id: cord-314320-juf6cx14
      author: Montazeri, Ali
       title: Some ethical concerns related to the coronavirus disease 2019 (COVID-19)
        date: 2020-05-27
       words: 792
      flesch: 55
     summary: These 2 vulnerable group should be treated with care and responsibility with regards to COVID-19 news. Although there are many important concerns related to coronavirus disease-19 (COVID-19), ethical issues should remain the top priority since the humanistic dimension of the recent pandemic is of prime importance.
    keywords: coronavirus; covid-19
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        item: #4698 of 7819
          id: cord-314343-u8u7nq44
      author: Sinclair, A.J.
       title: Age, frailty and diabetes – triple jeopardy for vulnerability to COVID-19 infection
        date: 2020-04-23
       words: 1134
      flesch: 38
     summary: In an epidemiological characterization and analysis of 72,314 cases of COVID-19 pneumonia reported in China, the majority of cases (89.8%) were between the age of 30 to 79 years old and the proportion of cases in the elderly (> 60 years) was 44.1%. Older age was also identified as a risk factor for mortality from COVID-19 pneumonia in a Chinese retrospective, multicentre cohort study {odds ratio (OR) 1.10, 95% confidence interval (CI) 1.03 to1.17, p = 0¢004)
    keywords: covid-19; diabetes; frailty; risk
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        item: #4699 of 7819
          id: cord-314347-4dsg2sxd
      author: Brondino, Natascia
       title: Effective Strategies for Managing COVID-19 Emergency Restrictions for Adults with Severe ASD in a Daycare Center in Italy
        date: 2020-07-09
       words: 2636
      flesch: 40
     summary: We retrospectively evaluated the effect of COVID-19 emergency restrictions and daycare center implementation on problem behaviors using our registry. The countermeasures and modifications of daycare center activities were put in place in order to comply to COVID-19 restrictions.
    keywords: asd; behaviors; covid-19; daycare; individuals; restrictions
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        item: #4700 of 7819
          id: cord-314349-rhm1ii3d
      author: Kraft, Miquel
       title: Incidence, features, outcome and impact on health system of de-novo abdominal surgical diseases in patients admitted with COVID-19
        date: 2020-08-28
       words: 2715
      flesch: 41
     summary: Sub-analyses were performed with a consecutive group of COVID-19 patients admitted during the study period, who did not require surgical consultation. COVID-19 patients might develop de-novo surgical diseases during hospitalization, requiring surgical consultation and treatment.
    keywords: consultation; covid-19; diseases; icu; patients; surgery
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        item: #4701 of 7819
          id: cord-314378-cs9ggqwk
      author: Singh, Prateush
       title: The Effects of a Novel Global Pandemic (COVID-19) on a Plastic Surgery Department
        date: 2020-04-29
       words: 1425
      flesch: 46
     summary: According to the National Audit Office, £16 billion is spent on elective NHS care per year, 8 with waiting lists for elective plastic surgery procedures up to 12 months long. We need clarity on the hierarchy of procedures that can be delayed, and such patients should be counseled by appropriate professionals to minimize the psychological outcomes of these cancellations.
    keywords: covid-19; patients; plastic; procedures
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        item: #4702 of 7819
          id: cord-314404-tkhupnko
      author: Ashokka, Balakrishnan
       title: Care of the Pregnant Woman with COVID-19 in Labor and Delivery: Anesthesia, Emergency cesarean delivery, Differential diagnosis in the acutely ill parturient, Care of the newborn, and Protection of the healthcare personnel
        date: 2020-04-10
       words: 2126
      flesch: 47
     summary: key: cord-314404-tkhupnko authors: Ashokka, Balakrishnan; Loh, May-Han; Tan, Cher Heng; SU, Lin Lin; Young, Barnaby Edward; Lye, David Chien; Biswas, Arijit; E Illanes, Sebastian; Choolani, Mahesh title: Care of the Pregnant Woman with COVID-19 in Labor and Delivery: Anesthesia, Emergency cesarean delivery, Differential diagnosis in the acutely ill parturient, Care of the newborn, and Protection of the healthcare personnel date: 2020-04-10 journal: Am J Obstet Gynecol DOI: 10.1016/j.ajog.2020.04.005 sha: doc_id: 314404 cord_uid: tkhupnko COVID-19 in pregnancy can cause severe maternal morbidity in up to 9% of affected gravidae. When a COVID-19 parturient with desaturation (oxygen saturation decreases to ≤93%) presents 256 for emergency cesarean delivery, general anesthesia needs to be administered.
    keywords: care; covid-19; delivery; oxygen; parturient; patient
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        item: #4703 of 7819
          id: cord-314423-6kuefmol
      author: Experton, B.
       title: A Multi-Factor Risk Model for Severe Covid-19 for Vaccine Prioritization and Monitoring Based on a 15 Million Medicare Cohort
        date: 2020-11-03
       words: 4852
      flesch: 33
     summary: The model affirms ethnicity (Black: OR 1.64; 95% CI 1.61-1.68, American Indian: OR 2.21; 95% CI 2.01-2.42), age over 85 (OR 1.75, 95% CI 1.69-1.81), the socio-economic factor of residing in a zip code in the lowest quartile of income (OR 1.23; 95% CI 1.21-1.26), ESRD (OR 2.35; 95% CI 2.25-2.45) and chronic lung disease (OR 1.95; 95% CI 1.90-2.00) as leading risk factors for Covid-19 hospitalizations, but reveals low risk for COPD (OR 1.15; 95% CI 1.13 -1.17) and minimal or no risk for diabetes (OR 1.03; CI 1.01-1.05), CHF (OR 1.10, 95% CI 1.08-1.12) or hypertension (OR 0.96; 95% CI 0.94-0.98), and demonstrates an association between prior herpes zoster immunization (OR 0.74; 95% CI 0.71-0.77), and to a lesser degree prior influenza and pneumococcal vaccines with less severe Covid-19. The regression analyses indicate that prior herpes zoster immunization (with the recombinant GlaxoSmithKline Shingrix ® vaccine) is also associated with lower odds of Covid-19 hospitalization or death (hospitalization OR 0.74; 95% CI 0.71-0.77; death OR 0.71; 95% CI 0.66-0.77).
    keywords: cases; covid-19; data; disease; hospitalization; medicare; model; preprint; risk; vaccine; variables
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        item: #4704 of 7819
          id: cord-314426-vwqjspfu
      author: Tang, Yuanji
       title: Epidemiology of COVID-19 in Brazil: using a mathematical model to estimate the outbreak peak and temporal evolution
        date: 2020-07-01
       words: 2055
      flesch: 59
     summary: COVID-19 cases in Ceara state started on 15 March 2020, where three people were diagnosed, all in Fortaleza city (the capital and epidemic epicentre in Ceara state). Our mathematical analysis shows that Sao Paulo state is at the peak of daily new cases (∼4000 daily cases), which would persist for some days before starting to drop.
    keywords: cases; covid-19; quarantine; state
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        item: #4705 of 7819
          id: cord-314466-6j4vuqer
      author: Kim, A. S.
       title: Transformed time series analysis of first-wave COVID-19: universal similarities found in the Group of Twenty (G20) Countries
        date: 2020-06-14
       words: 7655
      flesch: 55
     summary: Moreover, CCC profiles are analyzed with the same method for CCD profiles, i.e., for nation X, identification of the CCC onset day, calculation of time-shifting parameter m X c , and determination of the time-scaling parameter β X c . The primary research idea originated from the sequentially ordered patterns of CCD time series found in six nations on the European continent during the early stage of the pandemic spread, i.e., within 90 days.
    keywords: ccc; ccd; covid-19; data; italy; nations; number; profiles; time
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        item: #4706 of 7819
          id: cord-314468-9anuq5bt
      author: Billig, Jessica I.
       title: The Compounding Access Problem for Surgical Care: Innovations in the Post-COVID Era
        date: 2020-06-02
       words: 1142
      flesch: 43
     summary: To improve surgical access, an integrated health system approach is needed with proactive and innovative strategies to provide surgical care for all people. 4 Improving overall access to surgical care is important for patient outcomes.
    keywords: access; care; health; patients
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        item: #4707 of 7819
          id: cord-314512-60dk9zma
      author: Lorente, Leonardo
       title: Altas Concentraciones Séricas De Nitratos En Pacientes COVID-19 Fallecidos
        date: 2020-11-10
       words: 3100
      flesch: 38
     summary: To our knowledge, our series is the first one reporting serum nitrate levels in COVID-19 patients and the main new finding was the association between serum nitrate levels and mortality controlling for SOFA or APACHE-II. Thus, it is possible that if we had studied pulmonary autopsy specimens and serum nitrate levels during J o u r n a l P r e -p r o o f patient evolution, we would have observed in non-survivor patients persistently higher serum nitrate levels and a great angiogenesis in autopsies.
    keywords: apache; covid-19; levels; mortality; nitrate; nitric; oxide; patients; serum; sofa
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        item: #4708 of 7819
          id: cord-314614-rr0zckrv
      author: Huang, Jing
       title: Improving staff safety with checklists during novel coronavirus disease (COVID-19) pandemic: A quasi-experiment study in vascular surgical department
        date: 2020-08-07
       words: 1977
      flesch: 43
     summary: How to cite this article: Huang J, Liu X, Wu Z, Zhang L, Yang X. Improving staff safety with checklists during novel coronavirus disease (COVID-19) pandemic: a quasi-experiment study in vascular surgical department. key: cord-314614-rr0zckrv authors: Huang, Jing; Liu, Xiaoyan; Wu, Zhoupeng; Zhang, Lin; Yang, Xinghai title: Improving staff safety with checklists during novel coronavirus disease (COVID-19) pandemic: A quasi-experiment study in vascular surgical department date: 2020-08-07 journal: Medicine (Baltimore) DOI: 10.1097/md.0000000000021548 sha: doc_id: 314614 cord_uid: rr0zckrv Novel coronavirus disease (COVID-19) emerged in Wuhan in December 2019, has spread in many countries affected people globally.
    keywords: checklists; covid-19; pandemic; safety; surgery; workers
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        item: #4709 of 7819
          id: cord-314657-mqoqhr33
      author: Mahmud, Nadim
       title: Declining Cirrhosis Hospitalizations in the Wake of the COVID-19 Pandemic: A National Cohort Study
        date: 2020-05-06
       words: 1230
      flesch: 40
     summary: This was a retrospective cohort study of VHA cirrhosis hospitalizations using the Veterans Outcomes and Costs Associated with Liver Disease (VOCAL) cohort. In difference-in-differences analysis, weekly cirrhosis hospitalizations were on average 159.47 lower (95% confidence interval [CI] -250.03, -68.90) in the 2020 during-COVID period relative to an expected counterfactual trend (p<0.001; Figure 1 ; STable 1).
    keywords: cirrhosis; covid; covid-19; hospitalizations
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        item: #4710 of 7819
          id: cord-314660-ftcrf6c2
      author: Altamimi, H.
       title: The Outcome of COVID-19 Patients with Acute Myocardial Infarction
        date: 2020-07-27
       words: 3400
      flesch: 47
     summary: COVID-19 patients may present with acute myocardial infarction (AMI). Conclusion Contrary to previous small reports, overall in-hospital adverse events were low in this largest cohort of COVID-19 patients presenting with AMI.
    keywords: covid-19; license; medrxiv; patients; perpetuity; preprint
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        item: #4711 of 7819
          id: cord-314690-jc6cx76a
      author: Guha, Avirup
       title: Community and Socioeconomic Factors Associated with COVID-19 in the United States: Zip code level cross sectional analysis
        date: 2020-04-22
       words: 3007
      flesch: 46
     summary: Our results suggest that even though race, age, and gender were noted initially, zip code level population density is most significant. A multivariable linear regression model noted that 1% increase in the proportion of residents above the age of 65 years, proportion of African American residents, proportion of females, persons per household and population density of the zip code increased the proportion of positive cases by 0.77%, 0.23%, 1.64%, 1.83% and 0.46% respectively (P<0.01) with only population density remaining significant in zip codes with greater than median number of cases.
    keywords: cases; covid-19; population; preprint; proportion; zip
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        item: #4712 of 7819
          id: cord-314711-c6rqv4zd
      author: Pan, Jinhua
       title: Warmer weather unlikely to reduce the COVID-19 transmission: An ecological study in 202 locations in 8 countries
        date: 2020-09-09
       words: 3350
      flesch: 36
     summary: Yao et al. analyzed the association between temperature, relative humidity, and UV radiation with COVID-19 transmission rate in 62 Chinese cities and reported that warmer temperature could not mitigate the epidemic; besides, the relative humidity and UV radiation had no relationship with COVID-19 transmission in China (Yao et al., 2020) . Methods We collected daily numbers of COVID-19 cases in 202 locations in 8 countries.
    keywords: cases; covid-19; humidity; temperature; transmission
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        item: #4713 of 7819
          id: cord-314719-qi8gilkr
      author: Dawson, David L.
       title: COVID-19: Psychological Flexibility, Coping, Mental Health, and Wellbeing in the UK during the pandemic
        date: 2020-07-30
       words: 6990
      flesch: 27
     summary: The Lancet Psychiatry Comparing the reliability and validity of global self-report measures of subjective well-being with experiential day reconstruction measures The 1-year impact of severe acute respiratory syndrome on pulmonary function, exercise capacity, and quality of life in a cohort of survivors Psychological interventions for patients with cancer: psychological flexibility and the potential utility of Acceptance and Commitment Therapy Coronavirus Resource Center Coping and experiential avoidance: Unique or overlapping constructs Experiential avoidance as a generalized psychological vulnerability: Comparisons with coping and emotion regulation strategies Psychological flexibility as a fundamental aspect of health The PHQ-9: validity of a brief depression severity measure Quality of life and psychological status in survivors of severe acute respiratory syndrome at 3 months postdischarge Stress and psychological distress among SARS survivors 1 year after the outbreak An initial meta-analysis of Acceptance and Commitment Therapy for treating substance use disorders. However, psychological flexibility was significantly and positively associated with greater wellbeing, and inversely related to anxiety, depression, and COVID-19-related distress.
    keywords: anxiety; coping; covid-19; distress; flexibility; health; outcomes; pandemic; study; variables; wellbeing
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        item: #4714 of 7819
          id: cord-314733-fyximykl
      author: Butu, Alina
       title: The Impact of COVID-19 Crisis upon the Consumer Buying Behavior of Fresh Vegetables Directly from Local Producers. Case Study: The Quarantined Area of Suceava County, Romania
        date: 2020-07-29
       words: 11553
      flesch: 45
     summary: Regarding the manner of product selection, the questionnaire data and our research revealed the overwhelming inclination of fresh vegetable consumers to choose specific products and quantities, according to their own needs rather than buying a pre-defined basket. Regarding the manner of product selection, the questionnaire data and our research revealed the overwhelming inclination of fresh vegetable consumers to choose specific products and quantities, according to their own needs rather than buying a pre-defined basket. .
    keywords: age; behavior; buying; chains; consumers; covid-19; covid-19 crisis; crisis; figure; food; march; producers; respondents; supply; vegetables
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        item: #4715 of 7819
          id: cord-314736-jqgyln7b
      author: George, Ciju K.
       title: Emergency tracheostomy during COVID 19 Pandemic in a head and neck surgical oncology unit
        date: 2020-05-08
       words: 1046
      flesch: 44
     summary: key: cord-314736-jqgyln7b authors: George, Ciju K.; Varghese, Bipin T.; Divya, G.M.; Janardhan, Deepak; Thomas, Shaji title: Emergency tracheostomy during COVID 19 Pandemic in a head and neck surgical oncology unit date: 2020-05-08 journal: Oral Oncol DOI: 10.1016/j.oraloncology.2020.104784 sha: doc_id: 314736 cord_uid: jqgyln7b • Awake, Emergency, Intervention for an Unsecured 'Unable to intubate' Critical upper airway obstruction is a surgical challenge. We wish to share our experience on improvisations of emergency tracheostomies during the last one month of lockdown for COVID 19 in our region.
    keywords: airway; emergency; tracheostomy
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        item: #4716 of 7819
          id: cord-314767-iyvsxfsa
      author: Held, Michael B.
       title: Response to letter to the editor on “Elective orthopaedic surgeries during COVID-19 pandemic.”
        date: 2020-09-11
       words: 380
      flesch: 35
     summary: our 9 case differs from an elective total joint arthroplasty (TJA), as we presented a critically ill, 10 decompensated patient with active COVID-19 disease and an acute femoral neck fracture In conclusion, we appreciate the thoughtful response by the authors regarding our manuscript 44 describing a deliberate delay in surgery in a patient requiring THA with COVID-19. If deemed safe, specific 49 protocols, for all phases of care, must be followed to ensure safe and effective delivery of 50 important, but elective orthopaedic surgeries.
    keywords: covid-19
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        item: #4717 of 7819
          id: cord-314796-bek92zs9
      author: Hartung, Hans-Peter
       title: COVID-19 and management of neuroimmunological disorders
        date: 2020-05-22
       words: 1316
      flesch: 31
     summary: Whether MS increases the risk of contracting COVID-19 or COVID-19 increases MS disease activity is unclear. If a patient receiving ocrelizumab contracts COVID-19, delay of subsequent ocrelizumab infusions might be appropriate.
    keywords: cells; covid-19; disease; risk
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        item: #4718 of 7819
          id: cord-314810-ny4mnzqc
      author: Provenzi, Livio
       title: The Little Professor and the Virus: Scaffolding Children’s Meaning Making During the COVID-19 Emergency
        date: 2020-08-13
       words: 2138
      flesch: 21
     summary: The power of disconnection during the COVID-19 emergency: From isolation to reparation Unpacking the black box: How to promote citizen engagement through government social media during the COVID-19 crisis COVID-19 and Italy: what next? Measuring Italian Citizens′ Engagement in the First Wave of the COVID-19 Pandemic Containment Measures A Cross-sectional Study The role of parents parenting and the family environment in children's post-disaster mental health Risk factors for chronic post-traumatic stress disorder (PTSD) in SARS survivors Psychological status of parents of hospitalized children during the COVID-19 epidemic in China Maternal stress and sensitivity: Moderating effect of positive affect Emotional stress during pregnancy-associations with maternal anxiety disorders infant cortisol reactivity and mother-child interaction at pre-school age Maternal caregiving and DNA methylation in human infants and children: Systematic review Mother-infant attachment and the intergenerational transmission of posttraumatic stress disorder Intergenerational transmission of trauma effects: putative role of epigenetic mechanisms Parental advisory: maternal and paternal stress can impact offspring neurodevelopment Intergenerational effects of maternal PTSD: Roles of parenting stress and child sex Systematic review of pediatric health outcomes associated with childhood adversity PTSD as the second tsunami of the SARS-Cov-2 pandemic Infants' understanding of the link between visual perception and emotion Social cognition in the first year Child and adolescent emotion regulation: The role of parental emotion regulation and expression Infants' perseverative search errors are induced by pragmatic misinterpretation Fathers' versus mothers' social referencing signals in relation to infant anxiety and avoidance: a visual cliff experiment Maternal emotional signaling: Its effects on the visual cliff behavior of 1-year-olds Social referencing in infancy: Important findings and future directions In The everyday stress resilience hypothesis: A reparatory sensitivity and the development of coping and resilience Enhancing family resilience through family narrative co-construction Parental experiences of supporting children with clinically significant post-traumatic distress: A qualitative study of families accessing psychological services Mutual Regulation and Unique Forms of Implicit Relational Knowing Healing chronically traumatised children through their families/whanau Working and playing together: Prediction of preschool social-emotional competence from mother-child interaction Additionally, far from hinder this intuitive thinking, adults can engage in a careful listening of children emotional world and they can understand which are the elements contributing to the emergent meaning-making process that they are developing (32) .
    keywords: children; covid-19; making; meaning; parents
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        item: #4719 of 7819
          id: cord-314817-8ybegozg
      author: Patel, Priya
       title: Systemic Thrombolysis as Initial Treatment of COVID-19 Associated Acute Aortoiliac and Lower Extremity Arterial Thrombosis
        date: 2020-08-28
       words: 331
      flesch: 32
     summary: We describe a COVID-19 patient with acute limb ischemia secondary to macro-101 and micro-vascular thromboses at multiple levels, including a thrombosed aortic Acute limb ischemia in patients with COVID-197 19 pneumonia Acute limb ischemia in two young, non-200 atherosclerotic patients with COVID-19 Risk of Peripheral Arterial Thrombosis in 203 COVID-19 Angiogenesis in Covid-19 Treatment for COVID-19 Associated Acute Respiratory Distress Syndrome (ARDS): key: cord-314817-8ybegozg authors: Patel, Priya; Yu, Yasong; Zia, Saqib; Padberg, Frank; Curi, Michael; Huang, Joe title: Systemic Thrombolysis as Initial Treatment of COVID-19 Associated Acute Aortoiliac and Lower Extremity Arterial Thrombosis date: 2020-08-28 journal:
    keywords: covid-19
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        item: #4720 of 7819
          id: cord-314826-usfvulc2
      author: Sharifipour, Ehsan
       title: Evaluation of bacterial co-infections of the respiratory tract in COVID-19 patients admitted to ICU
        date: 2020-09-01
       words: 4346
      flesch: 38
     summary: key: cord-314826-usfvulc2 authors: Sharifipour, Ehsan; Shams, Saeed; Esmkhani, Mohammad; Khodadadi, Javad; Fotouhi-Ardakani, Reza; Koohpaei, Alireza; Doosti, Zahra; EJ Golzari, Samad title: Evaluation of bacterial co-infections of the respiratory tract in COVID-19 patients admitted to ICU date: 2020-09-01 journal: BMC Infect Dis DOI: 10.1186/s12879-020-05374-z sha: doc_id: 314826 cord_uid: usfvulc2 BACKGROUND: COVID-19 is known as a new viral infection. To date, few studies have investigated bacterial superinfections in COVID-19 patients.
    keywords: aureus; bacteria; baumannii; covid-19; icu; infections; mortality; patients; staphylococcus; study
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        item: #4721 of 7819
          id: cord-314829-tmgmqtjq
      author: Scohy, Anaïs
       title: Low performance of rapid antigen detection test as frontline testing for COVID-19 diagnosis
        date: 2020-05-21
       words: 1193
      flesch: 48
     summary: key: cord-314829-tmgmqtjq authors: Scohy, Anaïs; Anantharajah, Ahalieyah; Bodéus, Monique; Kabamba-Mukadi, Benoît; Verroken, Alexia; Rodriguez-Villalobos, Hector title: Low performance of rapid antigen detection test as frontline testing for COVID-19 diagnosis date: 2020-05-21 journal: J Clin Virol DOI: 10.1016/j.jcv.2020.104455 sha: doc_id: 314829 cord_uid: tmgmqtjq BACKGROUND: Recently, several easy to perform rapid antigen detection tests were developed and recommended in some countries as the first line of diagnostic.
    keywords: covid-19; samples; test
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        item: #4722 of 7819
          id: cord-314837-5nnlyavp
      author: Verhagen, Mark D.
       title: Forecasting spatial, socioeconomic and demographic variation in COVID-19 health care demand in England and Wales
        date: 2020-06-29
       words: 4149
      flesch: 41
     summary: By providing fine-grained estimates of expected hospitalization, we identify areas that face higher disproportionate health care burdens due to COVID-19, with respect to pre-crisis levels of hospital bed capacity. Hospital bed capacity for England was taken from NHS's SDCS data collection for both the general hospitalization bed capacity (collected December 2019) as well as the acute care bed capacity (collected January 2020)
    keywords: capacity; care; covid-19; demand; health; hospital; hospitalization; infection
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        item: #4723 of 7819
          id: cord-314843-vw8a1994
      author: Marijon, Eloi
       title: Out-of-hospital cardiac arrest during the COVID-19 pandemic in Paris, France: a population-based, observational study
        date: 2020-05-27
       words: 3828
      flesch: 40
     summary: OHCA survival rate to hospital admission was markedly reduced as well, leading to a major rise in OHCA-related deaths during the pandemic, which started declining at the end of the study period. We evaluated OHCA incidence and outcomes over a 6-week period during the pandemic in adult inhabitants of the study area.
    keywords: covid-19; hospital; incidence; ohca; pandemic; paris; patients; period
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        item: #4724 of 7819
          id: cord-314849-owqq0lev
      author: Apostolopoulos, Ioannis D.
       title: Covid-19: automatic detection from X-ray images utilizing transfer learning with convolutional neural networks
        date: 2020-04-03
       words: 2946
      flesch: 47
     summary: key: cord-314849-owqq0lev authors: Apostolopoulos, Ioannis D.; Mpesiana, Tzani A. title: Covid-19: automatic detection from X-ray images utilizing transfer learning with convolutional neural networks date: 2020-04-03 journal: Phys Eng Sci Med DOI: 10.1007/s13246-020-00865-4 sha: doc_id: 314849 cord_uid: owqq0lev In this study, a dataset of X-ray images from patients with common bacterial pneumonia, confirmed Covid-19 disease, and normal incidents, was utilized for the automatic detection of the Coronavirus disease. Despite the limitations of the current study, which are related to the data availability limitations, opens the horizons for more specialized research into the possible existence biomarkers related to the Covid-19 disease in X-ray images.
    keywords: cases; covid-19; images; learning; pneumonia
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        item: #4725 of 7819
          id: cord-314874-6ey87o16
      author: Palomar-Ciria, Nora
       title: COMMENTARY TO “SCHIZOPHRENIA AND COVID-19 DELIRIUM”, AN UPDATE
        date: 2020-11-04
       words: 567
      flesch: 51
     summary: key: cord-314874-6ey87o16 authors: Palomar-Ciria, Nora; Alonso-Álvarez, Daniel; Vázquez-Beltrán, Pilar; Blancodel Valle, Patricia title: COMMENTARY TO “SCHIZOPHRENIA AND COVID-19 DELIRIUM”, AN UPDATE date: 2020-11-04 journal: Psychiatry Res DOI: 10.1016/j.psychres.2020.113555 sha: doc_id: 314874 cord_uid: 6ey87o16 nan Since the outbreak of Coronavirus Disease 19 , atypical presentations that include neuropsychiatric conditions have been observed in infected patients (Nalleballe et al., 2020; Rogers et al., 2020) . Neuropsychiatric symptoms are present in more than half the cases (Romero-Sánchez et al., 2020) .
    keywords: covid-19
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        item: #4726 of 7819
          id: cord-314884-110nqkej
      author: Lansiaux, Édouard
       title: Covid-19 And Vit-D: Disease Mortality Negatively Correlates With Sunlight Exposure
        date: 2020-07-23
       words: 1554
      flesch: 37
     summary: In the current study, we applied a Pearson correlation test to public health as well as weather data, in order to assess the linear relationship between COVID-19 mortality rate and the sunlight exposure. In the current study, we applied a Pearson correlation test to public health as well as weather data, in order to assess the linear relationship between COVID-19 mortality rate and the sunlight exposure.
    keywords: correlation; covid-19; exposure; mortality; sunlight
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        item: #4727 of 7819
          id: cord-314889-lo3kkrfp
      author: Magrini, Stefano Maria
       title: Letter to the editor regarding “lack of supporting data make the risks of a clinical trial of radiation therapy as a treatment for COVID-19 pneumonia unacceptable”
        date: 2020-07-01
       words: 674
      flesch: 36
     summary: key: cord-314889-lo3kkrfp authors: Magrini, Stefano Maria; Katz, Matthew S.; Tomasini, Davide; Sasso, Giuseppe; Triggiani, Luca; di Monale e Bastia, Michela Buglione; Spiazzi, Luigi title: Letter to the editor regarding “lack of supporting data make the risks of a clinical trial of radiation therapy as a treatment for COVID-19 pneumonia unacceptable” date: 2020-07-01 journal: We agree with the authors that it is essential to conduct rigorous preclinical testing of low dose radiation therapy.
    keywords: covid-19; radiation
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        item: #4728 of 7819
          id: cord-314893-6zepsday
      author: Ho, Quan Yao
       title: Evaluating Potential Deceased Donor Renal Transplant Recipients for Asymptomatic COVID-19
        date: 2020-05-22
       words: 702
      flesch: 41
     summary: Our patient and her brother, her only household contact, were asymptomatic, had no known contact with COVID-19 cases or suspects, and had not travelled overseas for 3 months. A combination of clinical, molecular, and radiological investigations may help detect early COVID-19 but may not eliminate Practical considerations for solid organ transplantation during the COVID-19 global outbreak: the experience from Singapore COVID-19 in hemodialysis patients: a report of 5 cases Diagnostic performance of CT and reverse transcriptase-polymerase chain reaction for coronavirus disease 2019: a meta-analysis Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection FIGURE 1.
    keywords: chest; covid-19; patient
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        item: #4729 of 7819
          id: cord-314921-u74jut63
      author: LeVine, Shankar
       title: Case Report: The First Case of COVID-19 in Bhutan
        date: 2020-04-20
       words: 1735
      flesch: 44
     summary: In a recent study, 78.6% of COVID-19 patients suffered from a lack of appetite at presentation. JAMA e201585 Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study Immune responses in COVID-19 and potential vaccines: lessons learned from SARS and MERS epidemic Evaluation of the effectiveness of surveillance and containment measures for the first 100 patients with COVID-19 in Singapore Keeping the Coronavirus from Infecting Health-Care Workers.
    keywords: bhutan; case; country; covid-19; patient
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        item: #4730 of 7819
          id: cord-314942-eym2rh8v
      author: El Tabaa, Manar Mohammed
       title: New putative insights into neprilysin (NEP)-dependent pharmacotherapeutic role of roflumilast in treating COVID-19
        date: 2020-10-01
       words: 7654
      flesch: 28
     summary: Therefore, elevating cAMP 477 level within the pulmonary tissue, vascular and inflammatory cells can provide an 478 efficient anti-inflammatory action (Li et al., 2018) . As such, the newly 611 drug developing strategies are being directed to improve the therapeutic index of 612 Great efforts have been made to limit the gastrointestinal adverse reactions and to 614 provide a better benefit (Li et al., 2018) .
    keywords: angiotensin; anti; camp; cells; covid-19; endothelial; et al; il-6; inflammation; nep; patients; pulmonary; roflumilast; role; sars
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        item: #4731 of 7819
          id: cord-314948-7tnrfk24
      author: Borrás, A
       title: Pandemia del SARS-CoV-2 y reproducción asistida
        date: 2020-06-19
       words: 5420
      flesch: 38
     summary: El máximo nivel de expresión de ACE2 se registra en individuos de 30 años, situación que se muestra revertida en los testículos de hombres de 60 años, dado que se observa el nivel más bajo de expresión de ACE2 32,33 . En el caso de criopreservación de tejidos reproductores (tejido ovárico y testicular) se recomienda la utilización de tanques criogénicos específicos, independientemente del resultado del cribado y/o de las pruebas de cribado inmunológico a los pacientes.
    keywords: 2020; ace2; asistida; como; con; coronavirus; cov-2; covid-19; cribado; células; del; enfermedad; entre; expresión; infección; las; los; más; pacientes; pandemia; para; parte; por; presencia; que; recomendaciones; reproducción; sars; semen; sobre; también; testicular; una; virus
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        item: #4732 of 7819
          id: cord-315001-1ui27pkc
      author: Peterson, Nicholas
       title: Discovering Associations: Kawasaki Disease and COVID-19
        date: 2020-09-28
       words: 1597
      flesch: 49
     summary: e patient's mother had been working in a respiratory clinic during the COVID-19 pandemic, where patients presented for COVID-19 testing if they exhibited concerning symptoms; she reported wearing proper personal protective equipment (PPE) during all patient encounters at her workplace. COVID-19 testing resulted early in the course of admission but did not alter the management of the patient.
    keywords: covid-19; disease; fever; kawasaki; patient
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        item: #4733 of 7819
          id: cord-315006-w2wsaan5
      author: Abdoli, Amir
       title: Gossip, Rumors, and the COVID-19 Crisis
        date: 2020-07-27
       words: 545
      flesch: 48
     summary: The psychological and mental impact of coronavirus disease 2019 (COVID-19) on medical staff and general public -a systematic review and meta-analysis 5G networks and COVID-19 coronavirus: here are the latest conspiracy theories. It is suggested that more research will be conducted to identify the association of social media and COVID-19-related stress.
    keywords: covid-19; media
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        item: #4734 of 7819
          id: cord-315056-ohyb6oa0
      author: Xu, Juanjuan
       title: Clinical characteristics and outcomes of severe or critical COVID-19 patients presenting no respiratory symptoms or fever at onset
        date: 2020-10-29
       words: 4431
      flesch: 48
     summary: Due to the varied range of atypical symptoms in COVID-19 patients, it is difficult to diagnose atypical COVID-19 patients simply according to symptoms. key: cord-315056-ohyb6oa0 authors: Xu, Juanjuan; Yin, Zhengrong; Liu, Yu; Wang, Sufei; Duan, Limin; An, Yi; Fan, Jinshuo; Liao, Tingting; Jin, Yang; Chen, Jianguo title: Clinical characteristics and outcomes of severe or critical COVID-19 patients presenting no respiratory symptoms or fever at onset date: 2020-10-29 journal: Engineering (Beijing) DOI: 10.1016/j.eng.2020.09.009 sha: doc_id: 315056 cord_uid: ohyb6oa0 It is difficult to identify suspected cases of atypical patients with coronavirus disease 2019 (COVID-19), and data on severe or critical patients are scanty.
    keywords: admission; china; coronavirus; covid-19; fever; patients; sars; study; symptoms
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        item: #4735 of 7819
          id: cord-315058-t7bq4yqw
      author: Brand, Samuel P C
       title: Forecasting the scale of the COVID-19 epidemic in Kenya
        date: 2020-04-14
       words: 7572
      flesch: 42
     summary: We recreate this invisible period of spread by assuming that there have been five generations of undetected transmission in Nairobi before the first set of Kenyan symptomatic cases are determined. Therefore, we inferred agedependent symptomatic rates, using the age distribution of confirmed COVID-19 symptomatic cases in China, for a range of values of the relative infectiousness of asymptomatics to symptomatic infected individuals.
    keywords: age; cases; cov-2; covid-19; epidemic; kenya; license; preprint; rate; sars; transmission
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        item: #4736 of 7819
          id: cord-315064-2mgv9j6n
      author: Escher, Felicitas
       title: Detection of viral SARS‐CoV‐2 genomes and histopathological changes in endomyocardial biopsies
        date: 2020-06-12
       words: 3821
      flesch: 43
     summary: Nevertheless, SARS CoV-2 can potentially bind to its cellular ACE2 receptor in heart tissue cells and can therefore be detected in the heart muscle. If SARS CoV-2 can replicate in these target cells of the heart, this has to be investigated in subsequent analysis.
    keywords: cells; cov-2; covid-19; detection; embs; heart; infection; myocarditis; patients; sars
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        item: #4737 of 7819
          id: cord-315116-u7btx7nt
      author: Cabrera-Tasayco, Fiorella del Pilar
       title: Biosafety Measures at the Dental Office After the Appearance of COVID-19: A Systematic Review
        date: 2020-07-27
       words: 2894
      flesch: 41
     summary: In addition, in early April, the American Dental Association (ADA) published guidelines for protective measures in dental offices to maintain biosecurity and thereby minimize the risk of COVID-19 transmission before, during, and after dental care. Therefore, this literature review aims to determine the biosecurity measures required in dental offices after the appearance of COVID-19, seeking to provide dental health personnel with updates on the biosecurity and disinfection standards recommended to date, and their adaptation to the needs and ways of working of each.
    keywords: care; coronavirus; covid-19; dental; dentistry; health; patient
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        item: #4738 of 7819
          id: cord-315129-p31vm79o
      author: Bock, Jens-Ole
       title: Re-analysis of SARS-CoV-2-infected host cell proteomics time-course data by impact pathway analysis and network analysis: a potential link with inflammatory response
        date: 2020-06-23
       words: 3559
      flesch: 40
     summary: key: cord-315129-p31vm79o authors: Bock, Jens-Ole; Ortea, Ignacio title: Re-analysis of SARS-CoV-2-infected host cell proteomics time-course data by impact pathway analysis and network analysis: a potential link with inflammatory response date: 2020-06-23 journal: Aging (Albany NY) DOI: 10.18632/aging.103524 sha: doc_id: 315129 cord_uid: p31vm79o Coronavirus disease 2019 (COVID-19), caused by an outbreak of the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) in Wuhan, China, has led to an unprecedented health and economic crisis worldwide. Here, we use the publicly available proteomics data from this study to re-analyze the in vitro cellular consequences of SARS-CoV-2 infection by impact pathways analysis and network analysis.
    keywords: ace2; analysis; cov-2; covid-19; infection; pathway; proteins; sars
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        item: #4739 of 7819
          id: cord-315149-71bmj5il
      author: Caballero Bermejo, Antonio F.
       title: Sarilumab versus standard of care for the early treatment of COVID-19 pneumonia in hospitalized patients: SARTRE: a structured summary of a study protocol for a randomised controlled trial
        date: 2020-09-16
       words: 11238
      flesch: 40
     summary: Also, it will stick to the recommendations given by the consensus documents of the scientific journals3,4 to improve reliability and value of medical research literature by promoting transparent and accurate reporting of clinical research studies. The Principal Investigator may decide to conduct final analysis of study data at any time, even while some subjects may remain in long-term follow-up.
    keywords: clinical; consent; covid-19; data; dose; failure; following; il6; intervention; investigator; patients; protocol; sarilumab; soc; sponsor; study; treatment; trial
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        item: #4740 of 7819
          id: cord-315152-v3l33up6
      author: Figlerowicz, Magdalena
       title: First case of convalescent plasma transfusion in a child with COVID-19-associated severe aplastic anemia
        date: 2020-07-01
       words: 1708
      flesch: 52
     summary: Immunoprofile of white blood cells in a six-year-old girl with COVID-19-associated aplastic anemia in weeks 3 and 4. week 4 WBC total 10 3 /µl (4.00-12.00) 1.53 1.64 Neutrocytes % (25-60) Table 2 : WBC -white blood cells, NKnatural killer A novel coronavirus from patients with pneumonia in China Epidemiology of COVID-19 among children in China SARS-CoV-2 infection in children Coronavirus infection in children including COVID-19: An overview of the epidemiology, clinical features, diagnosis, treatment and prevention option in children Multisystem inflammatory syndrome in children during the COVID-19 pandemic: a case series Covid-19: consider cytokine storm syndrome and immunosuppression Treatment of patients with nonsevere and severe coronavirus disease 2019: an evidence-based guideline Effectiveness of convalescent plasma therapy in severe COVID-19 patients COVID-19-associated immune thrombocytopenia The epidemiology of acquired aplastic anemia Here, we present a case of using a J o u r n a l P r e -p r o o f convalescent plasma transfusion as a therapeutic method for severe pediatric COVID-19associated aplastic anemia.
    keywords: children; cov-2; covid-19; sars
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        item: #4741 of 7819
          id: cord-315157-2p45frlk
      author: Donell, Simon T.
       title: Preparation for the next COVID-19 wave: The European Hip Society and European Knee Associates recommendations
        date: 2020-08-17
       words: 4618
      flesch: 46
     summary: The theory of second waves is based on the 1918-1920 Spanish flu pandemic, which may have started in a US Army camp in Kansas, a British camp in Etaples in France, or possibly German concentration camps [19] . Close monitoring of the Rt value is essential in predicting the risk of a resurgence or second wave of a pandemic.
    keywords: arthroplasty; cases; covid-19; elective; hip; knee; orthopaedic; pandemic; patients; recommendations; wave
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        item: #4742 of 7819
          id: cord-315159-c9n8cro3
      author: Soni, Vivek Kumar
       title: Fight COVID-19 depression with immunity booster: Curcumin for psychoneuroimmunomodulation
        date: 2020-09-01
       words: 794
      flesch: 25
     summary: Major depression disorders (MDD) associate with disturbances in the hypothalamus-pituitary-adrenal (HPA) axis. Reports indicate the onset of post-traumatic stress disorder J o u r n a l P r e -p r o o f Chronic stress elevates proinflammatory cytokines (IL-1, IL-6, TNF-α) which triggers the production of catabolites of tryptophan (TRYCATs) through stimulation of indolamine-2,3-dioxygenase 2020); thus may improve MDD through PNI modulation.
    keywords: covid-19; curcumin; depression
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        item: #4743 of 7819
          id: cord-315166-ga6e3lqp
      author: Isoletta, Eugenio
       title: Emergency accesses in Dermatology Department during the Covid‐19 pandemic in a referral third level center in the north of Italy
        date: 2020-07-18
       words: 1696
      flesch: 50
     summary: Our aim was to evaluate the impact of the ongoing pandemic on the number of dermatological ED consultation, on the severity of cases presented to the ED with cutaneous symptoms, and on the diagnoses at discharge. The first finding emerging from our data was a dramatic reduction in the request for dermatological ED consultations during the COVID pandemic comparing to the same period in 2019, from 164 patients to 33, with an absolute difference of -79.9 percentage points ( Table 1 ).
    keywords: consultations; covid-19; patients
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        item: #4744 of 7819
          id: cord-315176-xafk1flg
      author: Sang, Hao
       title: A familial cluster of coronavirus disease 2019 (COVID-19) caused by one family member during his asymptomatic incubation period
        date: 2020-07-10
       words: 1021
      flesch: 40
     summary: The unsynchronized changes in the clinical symptoms and COVID-19 nucleic acid were found in this case, so consecutive nucleic acid detection of pretty suspected cases was recommended. Six family members in this family were tested for COVID-19 nucleic acid on 2 February, which resulted in the detection of another four COVID-19 patient.
    keywords: covid-19; patient; period
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        item: #4745 of 7819
          id: cord-315181-emf4i6ir
      author: Ryoo, Nayoung
       title: Coping with Dementia in the Middle of the COVID-19 Pandemic
        date: 2020-10-27
       words: 7142
      flesch: 33
     summary: However, current research report anosmia alone or in combination of parageusia among COVID-19 patients while they showed no significant nasal congestion or rhinorrhea as influenza or rhinovirus. This cytokine storm also triggers embolic cerebrovascular accidents, 14 and Li et al. 28 claims that hypercoagulable status of COVID-19 patients can lead to blood clots in both cerebral arteries and cerebral veins causing stroke and cerebral venous thrombosis.
    keywords: brain; care; coronavirus; covid-19; delirium; dementia; dementia patients; disease; health; home; infection; pandemic; patients; symptoms
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        item: #4746 of 7819
          id: cord-315188-a9pvugjt
      author: Choi, Min Hyuk
       title: Clinical Characteristics and Disease Progression in Early-Stage COVID-19 Patients in South Korea
        date: 2020-06-23
       words: 4149
      flesch: 39
     summary: In previous studies of COVID-19 patients [8, 12] , mild cases were defined as patients who experienced mild symptoms, with no manifestations of pneumonia on chest imaging. The use of the triage algorithm and KCDC classification for COVID-19 patients saves medical resources, allowing more efficient treatment and management of patients.
    keywords: cases; covid-19; disease; group; medical; patients; progression; study; symptoms; treatment
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        item: #4747 of 7819
          id: cord-315209-xpzqd0wk
      author: Kabamba Nzaji, Michel
       title: Predictors of Non-Adherence to Public Health Instructions During the COVID-19 Pandemic in the Democratic Republic of the Congo
        date: 2020-10-21
       words: 3091
      flesch: 44
     summary: The sample size was calculated using the following formula: n≥(Zα2.p.q)/d2, where the p represents the proportion of non-adherence to public health measures during the COVID-19 pandemic (we assumed that p=50% because this proportion in the DRC is unknown), q(1−p), z-value of the standard normal distribution corresponding to a significance level of alpha of 0.01 (2.58) and d the precision degree that we assumed to be 3% too. To reduce the COVID-19 transmission and impact, in the context of absence of vaccines or curative medical treatment, high adherence to public health measures is crucial.
    keywords: adherence; covid-19; health; measures; non; pandemic; public
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        item: #4748 of 7819
          id: cord-315246-b477kabe
      author: Dziedzic, Arkadiusz
       title: Special Care Dentistry and COVID-19 Outbreak: What Lesson Should We Learn?
        date: 2020-05-09
       words: 1286
      flesch: 35
     summary: The COVID-19 pandemic is undoubtedly posing the greatest challenge that special care dental services ever had to face, but we can learn from this situation and benefit from this challenge. Nowadays, we might clearly realize that dental care constitutes a crucial element in the whole healthcare system and public health maintenance, and, more importantly, that basic 'impactful dental interventions' are critical for pain management in general [4] .
    keywords: care; covid-19; patients
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        item: #4749 of 7819
          id: cord-315247-86ibo5gn
      author: Ćosić, Krešimir
       title: Artificial intelligence in prediction of mental health disorders induced by the COVID-19 pandemic among health care workers
        date: 2020-06-17
       words: 4738
      flesch: 14
     summary: key: cord-315247-86ibo5gn authors: Ćosić, Krešimir; Popović, Siniša; Šarlija, Marko; Kesedžić, Ivan; Jovanovic, Tanja title: Artificial intelligence in prediction of mental health disorders induced by the COVID-19 pandemic among health care workers date: 2020-06-17 journal: Croat Med J DOI: 10.3325/cmj.2020.61.279 sha: doc_id: 315247 cord_uid: 86ibo5gn The article proposes a methodology for prediction of mental health disorders induced by the pandemic, which includes: Phase 1) objective assessment of the intensity of HCWs’ stressor exposure, based on information retrieved from hospital archives and clinical records; Phase 2) subjective self-report assessment of stress during the COVID-19 pandemic experienced by HCWs and their relevant psychological traits; Phase 3) design and development of appropriate multimodal stimulation paradigms to optimally elicit specific neuro-physiological reactions; Phase 4) objective measurement and computation of relevant neuro-physiological predictor features based on HCWs’ reactions; and Phase 5) statistical and machine learning analysis of highly heterogeneous data sets obtained in previous phases.
    keywords: covid-19; data; disorders; features; hcws; health; neuro; pandemic; phase; physiological; prediction; stress
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        item: #4750 of 7819
          id: cord-315278-iv2zj67t
      author: Moazzam, Zorays
       title: Intussusception in an infant as a manifestation of COVID-19
        date: 2020-06-20
       words: 2170
      flesch: 46
     summary: Viral shedding in COVID-19 patients primarily occurs through nasal secretions, however, a fecooral route of transmission has also been postulated. Intussusception is the most common cause of bowel obstruction in infants, with up to 30% of pediatric intussusception cases having a preceding viral illness.
    keywords: children; cov-2; covid-19; intussusception; sars
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        item: #4751 of 7819
          id: cord-315287-vut5ayc2
      author: Otto, Catherine M
       title: Heartbeat: Heart disease and COVID-19
        date: 2020-07-08
       words: 974
      flesch: 27
     summary: In the accompanying editorial, Cheng and Leedy 2 discuss the likely pathophysiology of myocardial injury in patient with COVID-19 infection including unmasking of underlying cardiovascular disease, coronary plaque rupture and cytokine release syndrome. In a study from Wuhan, China, Zhang and colleagues 3 looked at the severity and outcomes of COVID-19 infection in patients with underlying CVD.
    keywords: covid-19; injury; patients
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        item: #4752 of 7819
          id: cord-315297-o8mwmjql
      author: Stephens, Elizabeth H.
       title: COVID-19: Crisis Management in Congenital Heart Surgery
        date: 2020-04-14
       words: 2828
      flesch: 35
     summary: While each hospital strives to carefully monitor and appropriately care for COVID-19 patients, in-house patients and healthcare providers may be positive prior to symptom onset or knowledge of their status, putting incoming surgical patients and their families at risk. Strategies to limit healthcare personnel exposure during the institution of ECMO and the care of COVID-19 patients on ECMO need also be employed.
    keywords: care; covid-19; exposure; patients; resources; risk; surgery
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        item: #4753 of 7819
          id: cord-315303-cxu5pt5r
      author: van Gerwen, Maaike
       title: Risk factors and outcomes of COVID‐19 in New York City; a retrospective cohort study
        date: 2020-07-24
       words: 3519
      flesch: 46
     summary: Importantly, population demographics, incidence rates and clinical outcomes for COVID-19 patients have been noted to vary significantly throughout different regions of the world. The present study assesses the risk factors associated with the need for hospitalization and mechanical ventilation as well as all-cause mortality of all laboratory confirmed COVID-19 patients, diagnosed across a larger New York City health system in the month of March 2020 and outcomes as of May 13th, 2020 with a minimum follow-up time of six weeks.
    keywords: adj; covid-19; patients; risk; ventilation
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        item: #4754 of 7819
          id: cord-315308-gk768lwy
      author: Gaughan, C.
       title: Religious affiliation and the risk of COVID 19 related mortality; a retrospective analysis of variation in pre and post lockdown risk by religious group in England and Wales.
        date: 2020-10-05
       words: 3539
      flesch: 41
     summary: Including the pre and post lockdown risk models give us an indication of the risk to non Christian religious groups of the uncontrolled spread of COVID, and how the risk to religious groups changed as the result of government measures. key: cord-315308-gk768lwy authors: Gaughan, C.; Ayoubkhani, D.; Nafilyan, V.; Goldblatt, P.; White, C.; Tingay, K.; Bannister, N. title: Religious affiliation and the risk of COVID 19 related mortality; a retrospective analysis of variation in pre and post lockdown risk by religious group in England and Wales. date: 2020-10-05 journal: nan DOI: 10.1101/2020.10.01.20204495 sha: doc_id: 315308 cord_uid: gk768lwy Background COVID 19 mortality risk is associated with demographic and behavioural factors; furthermore religious gatherings have been linked with the spread of COVID.
    keywords: covid; groups; lockdown; mortality; preprint; risk
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        item: #4755 of 7819
          id: cord-315310-j739aqso
      author: Farhoudian, A.
       title: A global survey on changes in the supply, price and use of illicit drugs and alcohol, and related complications during the 2020 COVID-19 pandemic
        date: 2020-07-21
       words: 6687
      flesch: 42
     summary: https://doi.org/10.1101/2020.07.16.20155341 doi: medRxiv preprint Others 8 4.5 Responders provided information about drug use changes in their countries during the COVID-19 pandemic. Details of drug use changes are reported in supplementary materials.
    keywords: alcohol; changes; countries; covid-19; drug; license; medrxiv; pandemic; preprint; responders; use
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        item: #4756 of 7819
          id: cord-315321-kax4gqhc
      author: Laplana, M.
       title: Lack of protective effect of chloroquine derivatives on COVID-19 disease in a Spanish sample of chronically treated patients
        date: 2020-09-09
       words: 2268
      flesch: 52
     summary: Independently of the exposure, both groups showed 138 the same prevalence of COVID-19 disease or suspected COVID-19 disease according to symptoms. COVID-19 disease prevalence was compared between treated and untreated-matched control sample.
    keywords: covid-19; license; medrxiv; preprint
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        item: #4757 of 7819
          id: cord-315343-ywgoqlxj
      author: Ribeiro, Haroldo V.
       title: City size and the spreading of COVID-19 in Brazil
        date: 2020-09-23
       words: 5475
      flesch: 52
     summary: This result shows that large cities have a lower prevalence of adults older than 60 years, such that a 1% increase in city population is associated with a 0.91% rise in the high-risk population. However, during the long-term course of the pandemic, this urban advantage vanishes and large cities start to exhibit higher incidence of cases and deaths, such that every 1% rise in population is associated with a 0.14% increase in the number of fatalities per capita after about four months since the first two daily deaths.
    keywords: cases; cities; city; covid-19; deaths; number
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        item: #4758 of 7819
          id: cord-315358-22srds0e
      author: Kovacs, George
       title: Just the Facts: Airway management during the coronavirus disease 2019 (COVID-19) pandemic
        date: 2020-03-30
       words: 1876
      flesch: 54
     summary: George Kovacs et al. Care for critically ill patients with COVID-19 Precautions for intubating patients with COVID-19 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Airway Management Guidelines for Patients with Known or Suspected COVID-19 Infection. It's different in that airway management of COVID-19 patients requires a paradigm shift from a focus primarily on patient-oriented outcomes to one that focuses on provider safety.
    keywords: airway; covid-19; intubation; patients; risk
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        item: #4759 of 7819
          id: cord-315367-e0frkhe6
      author: Du, Houwei
       title: The effect of vascular risk factor burden on the severity of COVID-19 illness, a retrospective cohort study
        date: 2020-09-21
       words: 3655
      flesch: 42
     summary: However, how the burden (number) of vascular risk factors influences the risk of severe COVID-19 disease remains unresolved. We evaluated the association between the number of vascular risk factors and the development of severe COVID-19 disease, using a Cox regression model.
    keywords: association; burden; covid-19; data; disease; factors; patients; risk; study
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        item: #4760 of 7819
          id: cord-315411-11mq8wll
      author: Rahman, Mohammad Azizur
       title: Neurobiochemical Cross-talk Between COVID-19 and Alzheimer’s Disease
        date: 2020-10-19
       words: 4127
      flesch: 38
     summary: CNS manifestations in about 25% of COVID-19 patients have been reported [3] . Plasma proteomics profiling also identified IL-6 among the most perturbed proteins in COVID-19 patients and marked as an indicator of disease severity [24] .
    keywords: alzheimer; cholinergic; cov-2; covid-19; disease; il-6; memory; patients; receptor; sars; system
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        item: #4761 of 7819
          id: cord-315414-aipfn5hi
      author: Antonio, Silverii Giovanni
       title: Are diabetes and its medications risk factors for the development of COVID-19? Data from a population-based study in Sicily
        date: 2020-10-01
       words: 1344
      flesch: 40
     summary: A recent meta-analysis of 83 observational studies enrolling 78,874 hospitalized patients with laboratory-confirmed COVID-19 showed a pooled prevalence of established diabetes of 14.34%; pre-existing diabetes was associated with higher risk of severe COVID-19 illness and in-hospital mortality 1 . Case fatality was significantly higher in SARS-CoV-2+ with DM (RR 4.5
    keywords: covid-19; diabetes; risk; sars
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        item: #4762 of 7819
          id: cord-315424-i3nnennw
      author: Willer, Brittany L.
       title: The otolaryngologist’s and anesthesiologist’s collaborative role in a pandemic: a large quaternary pediatric center’s experience with COVID-19 preparation and simulation
        date: 2020-06-10
       words: 2608
      flesch: 31
     summary: Since both the pediatric otolaryngologist and anesthesiologist are directly involved in emergency airway interventions, both specialties impact the safety of caring for COVID-19 patients and are a part of overall hospital pandemic preparedness. The following guidelines were developed as pathways for escalating airway expertise in COVID-19 patients: Once the anesthesiology team arrives, they assume all airway responsibilities and determine who remains in the room during endotracheal intubation.
    keywords: airway; covid-19; management; pandemic; patients; pediatric; team
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        item: #4763 of 7819
          id: cord-315428-uiezqa4p
      author: Tessler, Hannah
       title: The Anxiety of Being Asian American: Hate Crimes and Negative Biases During the COVID-19 Pandemic
        date: 2020-06-10
       words: 4637
      flesch: 43
     summary: Disease does not differentiate among people based on skin color or national origin, yet many Asian Americans have suffered from discrimination and hatred during the COVID-19 pandemic. With the COVID-19 pandemic, violent attacks and racial discrimination against Asian Americans have emerged as non-Asian Americans look for someone or something Asian to blame for their anger and fear about illness, economic insecurity, and stay-at-home orders.
    keywords: americans; asian; chinese; coronavirus; covid-19; crimes; hate; incidents; pandemic; states; united
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        item: #4764 of 7819
          id: cord-315440-he7sm7nj
      author: Wassie, Gizachew Tadesse
       title: Incubation period of SARS-CoV-2: A systematic review and meta-analysis
        date: 2020-10-11
       words: 3760
      flesch: 43
     summary: Sampling, data collection, reliability and validity of study tools, case definition, and study periods were assessed. key: cord-315440-he7sm7nj authors: Wassie, Gizachew Tadesse; Azene, Abebaw Gedef; Bantie, Getasew Mulat; Dessie, Getenet; Aragaw, Abiba Mihret title: Incubation period of SARS-CoV-2: A systematic review and meta-analysis date: 2020-10-11 journal: Curr Ther Res Clin Exp DOI: 10.1016/j.curtheres.2020.100607 sha: doc_id: 315440 cord_uid: he7sm7nj Background: Coronavirus disease (COVID-19) has currently become a major global public health problem.
    keywords: analysis; cov-2; covid-19; days; incubation; incubation period; period; sars; studies
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        item: #4765 of 7819
          id: cord-315453-mbv8vb2r
      author: Jean, Shio-Shin
       title: Old and re-purposed drugs for the treatment of COVID-19
        date: 2020-06-01
       words: 3470
      flesch: 32
     summary: This article summarizes old drugs that could be potentially re-purposed for COVID-19 treatment. It was recommended for COVID-19 treatment by the National Health Commission and State Administration of Traditional Chinese Medicine in the 7th edition of their report, 'Novel Coronavirus Pneumonia Diagnosis and Treatment Plan'
    keywords: clinical; coronavirus; covid-19; drugs; efficacy; hydroxychloroquine; patients; sars; treatment
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        item: #4766 of 7819
          id: cord-315457-w1nx9g91
      author: Siedner, Mark J
       title: Desperate times call for temperate measures: practicing infectious diseases during a novel pandemic
        date: 2020-04-21
       words: 1026
      flesch: 59
     summary: We are often asked to solve diagnostic and therapeutic dilemmas without the benefit of compelling clinical trial data. For a field of medicine that takes pride on its reliance on evidence and experience, these have been desperate times.
    keywords: covid-19; data; evidence
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        item: #4767 of 7819
          id: cord-315462-u2dj79yw
      author: Hewitt, Judith A.
       title: ACTIVating Resources for the COVID-19 Pandemic: In vivo Models for Vaccines and Therapeutics
        date: 2020-10-01
       words: 8974
      flesch: 35
     summary: Ferrets are considered good models for respiratory diseases as the physiology of their lung and airways are close to humans and they have been used extensively to model disease caused by many respiratory viruses including influenza (Thangavel and Bouvier, 2014) , RSV (Stittelaar et al., 2016) and SARS-CoV (van den Brand et al., 2008) . It bears emphasizing that mouse models that are not available from public repositories or commercial vendors cannot be scaled effectively to meet the high demand for animals and supply the high throughput needs of the community.
    keywords: ace2; animal; biorxiv; cov-2; covid-19; disease; et al; hamsters; human; infection; macaques; mice; models; mouse; sars; studies; vaccines; virus
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        item: #4768 of 7819
          id: cord-315465-u3zq9k5j
      author: de Jesus, Myrela Conceição Santos
       title: Family COVID-19 cluster analysis of an infant without respiratory symptoms
        date: 2020-08-26
       words: 1864
      flesch: 48
     summary: We report here the case of a child with COVID-19 whose main presentation comprised gastrointestinal symptoms without respiratory symptoms. Half of children may have gastrointestinal symptoms in the absence of respiratory symptoms 4 .
    keywords: child; covid-19; results; sars; symptoms
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        item: #4769 of 7819
          id: cord-315486-pjb5v1tc
      author: Wu, Xiaojun
       title: Different Laboratory Abnormalities in COVID-19 Patients with Hypertension or Diabetes
        date: 2020-09-30
       words: 1335
      flesch: 39
     summary: Are patients with hypertension and diabetes mellitus at increased risk for covid-19 infection? Effect of angiotensinconverting enzyme inhibition and angiotensin ii receptor blockers on cardiac angiotensin-converting enzyme 2 China Medical Treatment Expert Group for C (2020a) Comorbidity and its impact on 1590 patients with covid-19 in China: a nationwide analysis Clinical characteristics of coronavirus disease 2019 in China Risk factors associated with disease severity and length of hospital stay in covid-19 patients Temporal radiographic changes in covid-19 patients: relationship to disease severity and viral clearance Recent advances in immunity and hypertension Renin-angiotensin-aldosterone system inhibitors and risk of covid-19 Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in wuhan Clinical course and risk factors for mortality of adult inpatients with covid-19 in wuhan, China: a retrospective cohort study Sars-cov-2 viral load in upper respiratory specimens of infected patients Acknowledgements We acknowledge all the patients involved in this study, and appreciate all the frontline medical and nursing staff involved in the diagnosis and treatment of patients in Wuhan. What else might explain the poorer clinical outcomes of COVID-19 patients with hypertension or diabetes? To explore this question, we re-analysed the same cohort of 99 COVID-19 patients discharged from the general wards of Renmin Hospital of Wuhan University between 5 February 2020 and 14 March 2020 (Ethics approval No: WDRY2020-K124) (Liu et al. 2020a, b) .
    keywords: covid-19; diabetes; hypertension; patients
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        item: #4770 of 7819
          id: cord-315490-xs5v3uc3
      author: Kessler, Remi A.
       title: Neurosurgical management of brain and spine tumors in the COVID-19 era: an institutional experience from the epicenter of the pandemic
        date: 2020-05-05
       words: 3986
      flesch: 37
     summary: Due to the staggering number of COVID-19 patients, the Mount Sinai Health System has reallocated resources and space for patients who become oxygen dependent and may ultimately require mechanical ventilation. Nevertheless, our institutional experience and subsequent changes to patient management will inevitably differ given that our hospital is located in the epicenter of the pandemic across the US, and faces distinct challenges, including an intensive care unit that is currently at triple its normal full capacity due to COVID-19 patients.
    keywords: care; cases; coronavirus; covid-19; hospital; management; new; pandemic; patient; tumor
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        item: #4771 of 7819
          id: cord-315498-gpzee1f2
      author: Parkinson, N.
       title: Systematic review and meta-analysis identifies potential host therapeutic targets in COVID-19.
        date: 2020-09-01
       words: 4968
      flesch: 38
     summary: Results from identified studies, in the form of lists of implicated host factor genes, were combined using meta-analysis by information content (MAIC), 3 an approach we previously developed to identify host genes necessary for Influenza A virus (IAV) replication. We identified limited overlap of our gene list with host genes implicated in ARDS (innate immune and inflammation genes) and Influenza A virus infection (RNA-binding and ribosome-associated genes).
    keywords: analysis; covid-19; data; genes; host; license; list; maic; preprint; protein; sars; studies
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        item: #4772 of 7819
          id: cord-315508-8bcpxo02
      author: Sperotto, Francesca
       title: Cardiac manifestations in SARS-CoV-2-associated multisystem inflammatory syndrome in children: a comprehensive review and proposed clinical approach
        date: 2020-08-15
       words: 4412
      flesch: 40
     summary: compared patients meeting the MIS-C definition with classical KD or KDSS patients [20] , reporting that patients with MIS-C were generally older, had higher white blood cell count, neutrophil count, CRP, fibrinogen levels and higher troponin, as well as more profound lymphopenia, anemia, and lower platelet counts. Compared with KD patients without any signs of shock, KDSS patients were more frequently female, had a larger proportion of bands, higher CRP, and lower hemoglobin and platelet counts [42] .
    keywords: acute; cardiac; children; covid-19; disease; mis; multisystem; patients; syndrome
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        item: #4773 of 7819
          id: cord-315519-f4vwix3q
      author: Antony, Suresh J.
       title: Early Use of Tocilizumab in Respiratory Failure Associated with Acute COVID -19 Pneumonia in Recipients with Solid Organ Transplantation
        date: 2020-06-26
       words: 2223
      flesch: 45
     summary: key: cord-315519-f4vwix3q authors: Antony, Suresh J.; Singh, Joya; de Jesus, Mikhail; Lance, Jessalyn title: Early Use of Tocilizumab in Respiratory Failure Associated with Acute COVID -19 Pneumonia in Recipients with Solid Organ Transplantation date: 2020-06-26 journal: IDCases DOI: 10.1016/j.idcr.2020.e00888 sha: doc_id: 315519 cord_uid: f4vwix3q As of May 14, 2020, the World Health Organization has reported approximately 4.3 million cases of the novel Coronavirus Disease (COVID-19) with approximately 294,046 deaths worldwide.(1) Solid organ transplant recipients who are on chronic immunosuppressants fall within a special population of COVID-19 patients since they are more susceptible to complications secondary to COVID-19. Currently, we do not have data on treating COVID-19 patients with solid organ transplants with tocilizumab, an interleukin-6 (IL-6) inhibitor.
    keywords: covid-19; cytokine; il-6; patients; transplant
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        item: #4774 of 7819
          id: cord-315556-84rgd2s9
      author: Pilotto, A.
       title: Steroid-responsive severe encephalopathy in SARS-CoV-2 infection
        date: 2020-04-17
       words: 2337
      flesch: 41
     summary: Another important aspect is the hyperinflammation state secondary to COVID-19 infection, with massive release of cytokines and chemokines that could alter the permeability of blood-brain barrier (BBB). This hypothesis better fit with the short time relationship with COVID-19 infection and with the prompt response to steroid treatment.
    keywords: acquisition; covid-19; data; manuscript; medrxiv; preprint
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        item: #4775 of 7819
          id: cord-315569-e56c5g8h
      author: Aminian, Ali
       title: Bariatric Surgical Practice During the Initial Phase of COVID-19 Outbreak
        date: 2020-04-20
       words: 1807
      flesch: 40
     summary: Another small series of COVID-19 patients reported high morbidity and mortality in surgical patients [1] . The aim of this report is to describe the clinical presentation and outcomes of bariatric surgical patients during the initial phase of COVID-19 outbreak.
    keywords: covid-19; days; infection; patients; surgery
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        item: #4776 of 7819
          id: cord-315574-jq1p5t8w
      author: Copland, Michael
       title: Canadian Society of Nephrology COVID-19 Rapid Response Team Home Dialysis Recommendations
        date: 2020-05-29
       words: 4254
      flesch: 48
     summary: We have also suggested surgical mask use when members of the health team must interact with home dialysis patients due to the high risk of COVID-19 complications in this population. As the presentation of COVID-19 may be atypical in dialysis patients, we have suggested surgical mask use for patients who will be in contact with the health care team.
    keywords: care; covid-19; dialysis; health; home; mask; patients; team; training
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        item: #4777 of 7819
          id: cord-315576-bgcqkz0p
      author: Yamamoto, Naoki
       title: Apparent difference in fatalities between Central Europe and East Asia due to SARS-COV-2 and COVID-19: Four hypotheses for possible explanation
        date: 2020-08-05
       words: 6125
      flesch: 47
     summary: Although the weight of this habit in preventing virus infection is not clear at this moment, this difference indicates that Asians very clearly distinguish between outdoor and indoor in daily life. However, 21 our hypothesis suffers from the lack of analogous data available in other viral infections.
    keywords: asia; coronavirus; countries; cov-2; covid-19; east; europe; infection; number; people; sars; virus
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        item: #4778 of 7819
          id: cord-315585-bjij8ds7
      author: Wee, Liang En
       title: Respiratory surveillance wards as a strategy to reduce nosocomial transmission of COVID-19 through early detection: The experience of a tertiary-care hospital in Singapore
        date: 2020-05-08
       words: 3973
      flesch: 45
     summary: The average age of admitted patients was 68 years (SD, 17.49). CONCLUSIONS: Our institution successfully utilized the strategy of an RSW over a 6-week period to contain a cluster of COVID-19 cases and to prevent patient–HCW transmission.
    keywords: cases; covid-19; patients; rsw; sars; testing; transmission
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        item: #4779 of 7819
          id: cord-315587-jelh8o3v
      author: Dye, C.
       title: The scale and dynamics of COVID-19 epidemics across Europe
        date: 2020-06-29
       words: 3999
      flesch: 52
     summary: In Switzerland, the relatively flat peak in reported COVID-19 deaths (Fig 1 of the main text) differs from the estimated number of excess deaths (week 14), suggesting that COVID-19 deaths might have been under-reported in that week (Fig S4) . Here we investigate how the scale and dynamics of COVID-19 epidemics differ among 26 European countries in which the numbers of reported deaths varied more than 100-fold.
    keywords: countries; covid-19; deaths; epidemic; number; preprint
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        item: #4780 of 7819
          id: cord-315598-qwh72inx
      author: Mendoza, Jose Luis Accini
       title: ACTUALIZACION DE LA DECLARACIÓN DE CONSENSO EN MEDICINA CRITICA PARA LA ATENCIÓN MULTIDISCIPLINARIA DEL PACIENTE CON SOSPECHA O CONFIRMACIÓN DIAGNÓSTICA DE COVID-19
        date: 2020-10-06
       words: 69660
      flesch: 31
     summary: y los que tienen menos probabilidades de beneficiarse (él «demasiado enfermo»), no prestan suficiente atención a las diferencias entre grupos en términos de la duración de los cuidados intensivos necesarios para lograr resultados. Se recomienda aplicar la escala SOFA al menos cada 48 horas sumado al criterio de fragilidad y años de vida saludables salvados estos criterios podrían ser válidos en pacientes con fallo terapéutico a las medidas óptimas y orientar decisiones de deescalamiento de medidas y de nivel de complejidad de atención cuando la demanda potencial supera la oferta (capacidad y capacidades), estas decisiones deben ser tomadas idealmente en junta médica.
    keywords: 2019; 2020; acuerdo con; acute; además de; aguda; alto; amci; analysis; análisis de; asociado con; aumento de; bajo; calidad de; care; casos de; clinical; clínica; clínica de; clínicos; comité de; como el; como la; como los; como se; como una; compromiso; con covid-19; con el; con enfermedad; con hipoxemia; con infección; con la; con los; con mayor; con neumonía; con que; con sars; con sdra; con sospecha; con su; con un; condiciones de; considerar la; contar con; contra; control; coronavirus; cov-2; criterios de; crítico con; cual se; cuando se; cuenta la; de acuerdo; de aerosoles; de alta; de amci; de atención; de baja; de cada; de contaminación; de coronavirus; de covid-19; de cuidados; de de; de dificultad; de enfermedad; de esta; de estos; de estudios; de falla; de forma; de hcq; de hipoxemia; de il-6; de infección; de ingreso; de intubación; de la; de los; de manera; de marzo; de menor; de oxígeno; de pacientes; de protección; de salud; de ser; de soporte; de su; de tórax; de un; de ventilación; de vida; deben; del; del virus; dentro; desde el; después de; diagnóstico de; disease; disminución de; disminuir el; disponibilidad de; distress; donde; dosis; dosis de; duración de; durante la; días; días de; el consentimiento; el cual; el de; el diagnóstico; el día; el estudio; el grupo; el inicio; el manejo; el momento; el más; el nivel; el número; el paciente; el pronóstico; el riesgo; el sars; el tiempo; el traslado; el uso; elevación de; embargo; en china; en contra; en cuenta; en el; en este; en la; en los; en salud; en su; en uci; en un; entre el; entre la; entre los; es una; estado de; este; estrategia de; está; evidencia de; evitar la; fin de; final de; fue de; fuera de; fueron; grupo de; hasta el; horas; infección por; inicio de; intensive; la administración; la capacidad; la cual; la decisión; la disponibilidad; la enfermedad; la evidencia; la falla; la hcq; la hipoxemia; la infección; la intubación; la mortalidad; la oxigenación; la pandemia; la presencia; la presión; la relación; la respuesta; la salud; la seguridad; la terapia; la toma; la uci; la utilización; la valoración; la vida; la vía; las; los casos; los cuales; los días; los estudios; los síntomas; luego de; manejo de; mayor; mayoría de; mecánica; medición de; medidas de; mejorar la; mejoría; menor; más de; necesidad de; nivel de; niveles; número de; o por; o se; objetivo de; otros; pacientes con; pacientes covid-19; pacientes críticos; pacientes que; pacientes y; para el; para la; para los; para pacientes; para que; para sars; para su; parte de; patients; pcr; pero; personal de; plasma; por covid-19; por el; por la; por los; por sars; por un; posibilidad de; presión; protocolo de; pueden; pulmonar; punto de; que; que el; que la; que los; que puede; que se; que una; realización de; realizar; recomendación se; recomienda la; recomienda que; reducción de; renal; respiratoria; resultados; retiro de; review; riesgo de; salud y; sars; se debe; se han; se puede; se recomienda; según la; ser; severa; severidad de; shock; si el; si la; si se; sin; sobre el; sobre la; son de; sospecha de; syndrome; síndrome de; tasa de; tener; tener en; teniendo en; tiempo de; tipo de; todos los; tormenta de; trabajadores de; tratamiento de; treatment; uci y; un estudio; un paciente; una; unidad de; uso de; utilizar; ventilation; viral; y al; y cols; y como; y con; y de; y el; y en; y es; y la; y los; y para; y por; y puede; y que; y se; y su; y una
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        item: #4781 of 7819
          id: cord-315609-naqo1m0r
      author: Prayuenyong, Pattarawadee
       title: Clinical Implications of Chloroquine and Hydroxychloroquine Ototoxicity for COVID-19 Treatment: A Mini-Review
        date: 2020-05-29
       words: 3053
      flesch: 45
     summary: The characteristics of sensorineural hearing loss and/or tinnitus after chloroquine or hydroxychloroquine treatment can be temporary but reports of persistent auditory and vestibular dysfunction exist. Sensorineural hearing loss was identified after hydroxychloroquine treatment in five adults and two children.
    keywords: chloroquine; hearing; hydroxychloroquine; loss; ototoxicity; tinnitus
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        item: #4782 of 7819
          id: cord-315624-57kzulqv
      author: Storopoli, Jose
       title: Confidence in social institutions, perceived vulnerability and the adoption of recommended protective behaviors in Brazil during the COVID-19 pandemic
        date: 2020-10-27
       words: 5801
      flesch: 40
     summary: During a global COVID-19 pandemic, the public depends on the media to convey accurate information in order to make informed decisions regarding health protective behavior (Garfin, Silver and Holman, 2020) . Using recreancy theory, we explored the relationship between confidence, perceived risk and social behavior in the presence of social risks (Freudenburg, 1993) .
    keywords: adoption; behaviors; confidence; government; health; institutions; measures; risk; trust; vulnerability
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        item: #4783 of 7819
          id: cord-315634-fkm6slkc
      author: Jouffroy, Romain
       title: Hypoxemia Index Associated with Prehospital Intubation in COVID-19 Patients
        date: 2020-09-20
       words: 4061
      flesch: 39
     summary: key: cord-315634-fkm6slkc authors: Jouffroy, Romain; Kedzierewicz, Romain; Derkenne, Clement; Bertho, Kilian; Scannavino, Marine; Frattini, Benoit; Lemoine, Frederic; Jost, Daniel; Prunet, Bertrand title: Hypoxemia Index Associated with Prehospital Intubation in COVID-19 Patients date: 2020-09-20 journal: J Clin Med DOI: 10.3390/jcm9093025 sha: doc_id: 315634 cord_uid: fkm6slkc Background: There exists a need for prognostic tools for the early identification of COVID-19 patients requiring prehospital intubation. Conclusion: An HI of <1.3 was associated with a 3-fold increase in prehospital intubation among COVID-19 patients.
    keywords: covid-19; intubation; patients; prehospital
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        item: #4784 of 7819
          id: cord-315656-asvf4roo
      author: Wu, Junjiao
       title: Revisiting the Immune Balance Theory: A Neurological Insight Into the Epidemic of COVID-19 and Its Alike
        date: 2020-10-15
       words: 5947
      flesch: 25
     summary: Studies have shown that increased numbers of pro-inflammatory cytokines (such as IL-1β, IL-6, IL-12, IFN-γ, IP10, and MCP1) in the serum of severe SARS patients are associated with lung inflammation and extensive lung injury (46) . Although fever and pneumonia are typical symptoms, COVID-19 patients exhibit multiple neurological complications.
    keywords: ace2; brain; cells; coronavirus; cov-2; covid-19; cytokine; disease; infection; patients; potential; sars; system
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        item: #4785 of 7819
          id: cord-315681-p3j8kt80
      author: Wiley, Lindsay F
       title: Public Health Law and Science in the Community Mitigation Strategy for Covid-19
        date: 2020-05-08
       words: 8186
      flesch: 42
     summary: 68 Judge LaVerdiere ultimately determined that Hickox could properly be subjected to an order mandating direct active monitoring (with direct observation by state health authorities at least once per day to review symptoms and monitor temperature with a second daily follow-up by phone), a less restrictive limitation on her liberty than the home quarantine restrictions the state had requested. Although the law governing public health emergency orders is surprisingly unsettled, public health law experts widely agree that an assessment of the necessity, effectiveness, and scientific rationale for intrusive measures is a key feature of judicial review.
    keywords: cdc; community; court; covid-19; disease; guidelines; health; measures; orders; people; public; quarantine; restrictions; spread; state
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        item: #4786 of 7819
          id: cord-315685-ute3dxwu
      author: Ehaideb, Salleh N.
       title: Evidence of a wide gap between COVID-19 in humans and animal models: a systematic review
        date: 2020-10-06
       words: 5553
      flesch: 45
     summary: key: cord-315685-ute3dxwu authors: Ehaideb, Salleh N.; Abdullah, Mashan L.; Abuyassin, Bisher; Bouchama, Abderrezak title: Evidence of a wide gap between COVID-19 in humans and animal models: a systematic review date: 2020-10-06 journal: Crit Care DOI: 10.1186/s13054-020-03304-8 sha: doc_id: 315685 cord_uid: ute3dxwu BACKGROUND: Animal models of COVID-19 have been rapidly reported after the start of the pandemic. Inclusion criteria were the establishment of animal models of COVID-19 as an endpoint.
    keywords: animal; cov-2; covid-19; human; lung; mice; models; response; sars; studies; virus
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        item: #4787 of 7819
          id: cord-315693-w60craan
      author: del Pilar Estevez-Diz, Maria
       title: Management of cervical cancer patients during the COVID-19 pandemic: a challenge for developing countries
        date: 2020-06-17
       words: 2864
      flesch: 37
     summary: key: cord-315693-w60craan authors: del Pilar Estevez-Diz, Maria; Bonadio, Renata Colombo; Miranda, Vanessa Costa; Carvalho, Jesus Paula title: Management of cervical cancer patients during the COVID-19 pandemic: a challenge for developing countries date: 2020-06-17 journal: Ecancermedicalscience DOI: 10.3332/ecancer.2020.1060 sha: doc_id: 315693 cord_uid: w60craan During the COVID-19 pandemic, health services worldwide are going through important adaptations to assist patients infected with COVID-19, at the same time as continuing to provide assistance to other potentially life-threatening diseases. Cervical cancer patients are a particularly delicate group due to patients' young ages and the potentially curative disease for the majority of cases, occurring mainly in LMICs.
    keywords: cancer; covid-19; health; pandemic; patients; therapy; treatment
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        item: #4788 of 7819
          id: cord-315696-43wmazxa
      author: Marinaki, Smaragdi
       title: A Systematic Review of COVID-19 Infection in Kidney Transplant Recipients: A Universal Effort to Preserve Patients’ Lives and Allografts
        date: 2020-09-16
       words: 6026
      flesch: 40
     summary: Initial report from the US epicenter Infection in solid-organ transplant recipients COVID-19 in kidney transplant recipients A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement Coronavirus Disease (COVID-19) in Kidney and Liver Transplant Patients: A Single-Center Experience Interleukin-6 receptor antagonist therapy to treat SARS-CoV-2 driven inflammatory syndrome in a kidney transplant recipient Threatening drug-drug interaction in a kidney transplant patient with coronavirus disease 2019 (COVID-19) A catabolic state in a kidney transplant recipient with COVID-19 Immunosuppressive therapy maintenance in a kidney transplant recipient with SARS-CoV-2 pneumonia: A case report A familial cluster, including a kidney transplant recipient Coronavirus disease 2019 in renal transplant recipients: Report of two cases COVID-19) in a Renal Transplant Patient Fatal SARS-CoV-2 infection in a renal transplant recipient COVID-19 pneumonia in a kidney transplant recipient successfully treated with tocilizumab and hydroxychloroquine COVID-19 in kidney transplant recipients Case report of COVID-19 in a kidney transplant recipient: Does immunosuppression alter the clinical presentation? Should cyclosporine be useful in renal transplant recipients affected by SARS-CoV-2? SARS-CoV-2 infection in kidney transplant recipients:
    keywords: case; covid-19; disease; infection; kidney; ktx; outcomes; patients; recipients; renal; transplant; transplantation
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        item: #4789 of 7819
          id: cord-315730-fzgxuak7
      author: Penman, Sophie L.
       title: Safety perspectives on presently considered drugs for the treatment of COVID‐19
        date: 2020-07-17
       words: 12087
      flesch: 30
     summary: As such, it is likely that many of the AEs observed in the Ebola study will translate to COVID-19 patients treated with remdesivir. However, a recent study found that only 4.1 % of COVID-19 patients receiving remdesivir treatment suffered serious (grade 3 or 4) transaminase elevations, with there being no significant difference between the remdesivir-and placebo-treated groups (Beigel et al., 2020) .
    keywords: anakinra; arthritis; baricitinib; coronavirus; cov-2; covid-19; covid-19 patients; disease; dose; drug; et al; hydroxychloroquine; ifn; infection; liver; patients; potential; remdesivir; rheumatoid; risk; safety; sars; study; tocilizumab; treatment; trial; use
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        item: #4790 of 7819
          id: cord-315735-0a49okho
      author: Matrajt, Laura
       title: Evaluating the effectiveness of social distancing interventions against COVID-19
        date: 2020-03-30
       words: 4288
      flesch: 49
     summary: key: cord-315735-0a49okho authors: Matrajt, Laura; Leung, Tiffany title: Evaluating the effectiveness of social distancing interventions against COVID-19 date: 2020-03-30 journal: nan DOI: 10.1101/2020.03.27.20044891 sha: doc_id: 315735 cord_uid: 0a49okho SARS-CoV-2 has infected over 140,000 people as of March 14, 2020. We use a mathematical model to investigate the effectiveness of social distancing interventions lasting six weeks in a middle-sized city in the US.
    keywords: adults; cases; distancing; epidemic; interventions; license
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        item: #4791 of 7819
          id: cord-315744-nr0fu2qb
      author: Wang, Yu
       title: Reduction of secondary transmission of SARS-CoV-2 in households by face mask use, disinfection and social distancing: a cohort study in Beijing, China
        date: 2020-05-28
       words: 3502
      flesch: 47
     summary: The risk of household transmission was 18 times higher with frequent daily close contact with the primary case (OR=18.26, 95% CI 3.93 to 84.79), and four times higher if the primary case had diarrhoea (OR=4.10, 95% CI 1.08 to 15.60). The risk of household transmission was 18 times higher with frequent daily close contact with the primary case (OR=18.26, 95% CI 3.93 to 84.79), and four times higher if the primary case had diarrhoea (OR=4.10, 95% CI 1.08 to 15.60).
    keywords: case; covid-19; families; household; mask; risk; transmission
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        item: #4792 of 7819
          id: cord-315756-g6g34uvh
      author: Danchin, A.
       title: Immunity after COVID-19: protection or sensitization ?
        date: 2020-05-23
       words: 4283
      flesch: 54
     summary: wheref = k f k π k ,d = k d k f k /f .
    keywords: age; class; covid-19; epidemic; infection
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        item: #4793 of 7819
          id: cord-315772-jt3vjsqe
      author: Kivi, Marie
       title: Up and about: Older adults’ wellbeing during the COVID-19 pandemic in a Swedish longitudinal study
        date: 2020-06-30
       words: 3004
      flesch: 56
     summary: We analyzed annual changes in four aspects of wellbeing over five years (2015–2020): life satisfaction, financial satisfaction, self-rated health, and loneliness in a subsample (n=1071, aged 60–71) from a larger survey of Swedish older adults. In sum, Swedish older adults were still 'up and about' during the early part of the COVID-19 pandemic; while the majority practiced social distancing, they also rated their wellbeing as high as, or even higher than they did five years prior.
    keywords: covid-19; health; risk; wellbeing
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        item: #4794 of 7819
          id: cord-315827-biur1xn4
      author: Zickfeld, Janis H.
       title: Correlates of Health-Protective Behavior During the Initial Days of the COVID-19 Outbreak in Norway
        date: 2020-10-06
       words: 12186
      flesch: 42
     summary: Experiences from previous disease outbreaks such as Ebola, SARS, and the swine flu suggests that psychological factors including attitudes and affective reactions have a significant impact on whether individuals adopt health protective behavior or not (e.g., Tang and Wong, 2003; Bish and Michie, 2010; Bults et al., 2011) . Perceived likelihood of being infected was not a significant predictor of engagement with health behaviors.
    keywords: age; behavior; covid-19; data; distancing; engagement; et al; health; march; outbreak; participants; people; risk; sample; variables
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        item: #4795 of 7819
          id: cord-315849-e16lln3f
      author: Takayama, Kazuo
       title: In vitro and Animal Models for SARS-CoV-2 research
        date: 2020-05-30
       words: 1172
      flesch: 45
     summary: Interestingly, virus infection impaired the bile acid transporting functions of cholangiocytes [20] . One of the works that set the pace for discovery of animal models was by Zhou et al. who conducted SARS-CoV-2 infection experiments using HeLa cells that expressed ACE2 proteins taken from multiple animal species from mice to humans
    keywords: cov-2; covid-19; infection; sars
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        item: #4796 of 7819
          id: cord-315864-zadogqiu
      author: Davido, Benjamin
       title: nImpact of medical care including anti-infective agents use on the prognosis of COVID-19 hospitalized patients over time
        date: 2020-08-02
       words: 3623
      flesch: 39
     summary: Indeed, in the absence of a clear recommendation for treatment initiation, it is difficult to assume or to invalidate the effect of anti-infective agents on the prognosis of COVID-19 patients. However, it was carried out in a hospital specialized for decades in the Moreover, considering inherent limitation of a descriptive study with a limited sample size (n=132), we could not infer causality in the association between the use of AZI±HCQ and the ameliorated prognosis in COVID-19 patients.
    keywords: agents; azithromycin; covid-19; hcq; icu; patients; study; treatment
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        item: #4797 of 7819
          id: cord-315886-f4ofmdcm
      author: Karim, A.
       title: Knowledge and attitude towards COVID-19 in Bangladesh: Population-level estimation and a comparison of data obtained by phone and online survey methods
        date: 2020-05-26
       words: 6185
      flesch: 49
     summary: We found that, the total knowledge score was still significantly higher in the online non-medical participants than that of phone survey participants in most of the socio-demographic groups. Based on this criterion, we found that 75.1% of the online non-medical participants had good knowledge which was significantly higher than that of phone survey participants.
    keywords: covid-19; knowledge; level; medical; participants; phone; population; score; study; survey
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        item: #4798 of 7819
          id: cord-315920-9p6ar3cr
      author: Quigley, Denise D.
       title: COVID‐19 Preparedness in Nursing Homes in the Midst of the Pandemic
        date: 2020-05-12
       words: 913
      flesch: 46
     summary: Staff shortages focused on licensed staff. Common strategies to address staff shortages included having staff volunteer for extended hours (55%) and nonclinical staff filling different roles (45%).
    keywords: covid-19; homes; nursing; staff
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        item: #4799 of 7819
          id: cord-315930-1vgb2mk0
      author: Andrianopoulos, Ioannis
       title: Tocilizumab's efficacy in patients with Coronavirus Disease 2019 (COVID‐19) is determined by the presence of cytokine storm
        date: 2020-06-29
       words: 826
      flesch: 29
     summary: 12 Tociluzumab challenge: a series of cytokine storm therapy experience in hospitalized COVID-19 pneumonia patients Impact of low dose tocilizumab on mortality rate in patients with COVID-19 related pneumonia Tocilizumab therapy reduced intensive care unit admissions and/or mortality in COVID-19 patients Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: a single center study of 100 patients in Brescia Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in patients with severe COVID-19 Tocilizumab treatment in COVID-19: a single center experience Tocilizumab for treatment of severe COVID-19 patients: preliminary results from Smatteo COVID-19 registry (SMACORE). key: cord-315930-1vgb2mk0 authors: Andrianopoulos, Ioannis; Papathanasiou, Athanasios; Papathanakos, Georgios; Chaidos, Aristeidis; Koulouras, Vasilios title: Tocilizumab's efficacy in patients with Coronavirus Disease 2019 (COVID‐19) is determined by the presence of cytokine storm date: 2020-06-29 journal: J Med Virol DOI: 10.1002/jmv.26209 sha: doc_id: 315930 cord_uid: 1vgb2mk0 We read with great interest the research article written by Borku Uysal B et al which is in accordance with the so far accumulating knowledge that tocilizumab is an effective treatment for COVID-19 cytokine storm syndrome (CSS).
    keywords: covid-19; patients; tocilizumab
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        item: #4800 of 7819
          id: cord-315952-gh002ldb
      author: Ahmadi, Khodabakhsh
       title: Iranian Emotional Experience and Expression During the COVID-19 Crisis
        date: 2020-07-07
       words: 908
      flesch: 44
     summary: Iranian people, similar to other populations, may experience fear as an adaptive emotion. Due to the common purpose and unity of Iranian people in eradicating COVID-19, they have experienced shame adaptively; only some groups, who have lost their jobs due to the pandemic, feel worthless.
    keywords: covid-19; pandemic; people
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        item: #4801 of 7819
          id: cord-315959-glaaaqbt
      author: Santos Leite Pessoa, Mariana
       title: Multisystemic Infarctions in COVID-19: Focus on the Spleen
        date: 2020-06-03
       words: 921
      flesch: 35
     summary: COVID-19 and haemostasis: a position paper from Italian Society on Thrombosis and Haemostasis (SISET) Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up Incidence of thrombotic complications in critically ill ICU patients with COVID-19 SARS-CoV-2 and viral sepsis: observations and hypotheses Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis D-dimer is associated with severity of coronavirus disease 2019 (COVID-19): a pooled analysis COVID-19: consider cytokine storm syndromes and immunosuppression Diagnosis, prevention and treatment of thromboembolic complications in COVID-19: report of The National Institute of Public Health for the Netherlands Pathological changes of the spleen in ten patients with new coronavirus infection by minimally invasive autopsies LEARNING POINTS: Thrombotic disease as a complication of COVID-19 must be suspected by clinicians, and recognized and monitored by radiologists.
    keywords: covid-19; disease; patients
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        item: #4802 of 7819
          id: cord-315961-rnzy0wlr
      author: Fang, Nancy Z.
       title: A hospital-based COVID-19 abortion case in the early phase of the pandemic()
        date: 2020-05-19
       words: 982
      flesch: 48
     summary: Routine preoperative testing could identify COVID-19 positive patients but may not be widely available. We recommend staff providing surgical abortion or anesthesia universally use PPE advised for COVID-19 positive patients in settings with high rates of community transmission.
    keywords: care; covid-19; hospital
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        item: #4803 of 7819
          id: cord-315970-m5o962yw
      author: Di Ciaula, Agostino
       title: COVID‐19, internists and resilience: the north‐south Italy outbreak.
        date: 2020-06-01
       words: 3986
      flesch: 44
     summary: On May 20, infected subjects were 26,596 and COVID-19 related deaths were 2,454, about 7-and 12-fold lower, respectively, than in northern Italy. The staff was therefore re-located in the so-called grey zone equipped with up to 64 beds, occupying the whole 5th floor of the Asclepios block, a 5-floor building entirely dedicated to COVID-19 patients (Figure 4) .
    keywords: article; covid-19; deaths; health; infection; italy; northern; number; patients; subjects
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        item: #4804 of 7819
          id: cord-315991-uecdbanf
      author: Hughes, David
       title: The Australian Institute of Sport Framework for Rebooting Sport in a COVID-19 Environment
        date: 2020-05-06
       words: 10316
      flesch: 51
     summary: Sport Organisations and athletes will be faced with complex decisions 821 regarding resumption of training activities in the current circumstances. Non-contact skills training.
    keywords: aerobic; agility training; athletes; contact; covid-19; drills; groups; health; non; resistance training; running; skills; solo; sport; sporting; staff; total; training
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        item: #4805 of 7819
          id: cord-316006-t080mykk
      author: Kong, Dechuan
       title: Clusters of 2019 coronavirus disease (COVID‐19) cases in Chinese tour groups
        date: 2020-07-27
       words: 3199
      flesch: 54
     summary: In recent studies, clusters of COVID-19 cases have been principally identified in family settings (Bai et al., 2020; Chan et al., 2020) . Our study describes clusters of COVID-19 cases within tour groups travelling in European countries from January 16 through 28.
    keywords: cases; china; covid-19; group; study; tour; transmission
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        item: #4806 of 7819
          id: cord-316029-z708c3ex
      author: Brunsdon, Priya
       title: Clinical Pharmacology Considerations for Developing Small‐Molecule Treatments for COVID‐19
        date: 2020-07-12
       words: 4969
      flesch: 32
     summary: A systematic review Gentamicin volume of distribution in critically ill septic patients Antimicrobial pharmacokinetic and pharmacodynamic issues in the critically ill with severe sepsis and septic shock Effect of alpha-1-acid glycoprotein binding on pharmacokinetics and pharmacodynamics Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Impact of infectious and inflammatory disease on cytochrome P450-mediated drug metabolism and pharmacokinetics The Impact of Renal Impairment on Patient Drug Response -Assessing the Need for a Consensus Approach Acute kidney injury in patients hospitalized with COVID-19 Kidney involvement in COVID-19 and rationale for extracorporeal therapies COVID-19 and kidney failure in the acute care setting: our experience from Seattle Pharmacokinetic principles during continuous renal replacement therapy: drugs and dosage Assessment of the impact of renal impairment on systemic exposure of new molecular entities: evaluation of recent new drug applications Hydroxychloroquine as an aerosol might markedly reduce and even prevent severe clinical symptoms after SARS-CoV-2 infection Virological assessment of hospitalized patients with COVID-2019 Working to supply remdesivir for COVID-19 Inhalation drug delivery devices: technology update A review of nebulized drug delivery in COPD Determination of the relative bioavailability of salbutamol to the lungs and systemic circulation following nebulization Practical strategies for a safe and effective delivery of aerosolized medications to patients with COVID-19 A guide to drug therapy in patients with enteral feeding tubes: dosage form selection and administration methods Therapeutic concerns when oral medications are administered nasogastrically Clogged feeding tubes: a clinician's thorn Medication administration through enteral feeding tubes Estimates of the severity of coronavirus disease 2019: a model-based analysis A call for the appropriate application of clinical pharmacological principles in the search for safe and efficacious COVID-19 (SARS-COV-2) treatments Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease Rates of Cases, Hospitalizations and Deaths by Race/Ethnicity Group COVID-19: They are based on the major observed disease complications that impact drug absorption, distribution, metabolism, and elimination.
    keywords: absorption; acute; administration; covid-19; disease; dosing; drug; hemodialysis; patients; therapies; treatment
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        item: #4807 of 7819
          id: cord-316047-d9cpe9yl
      author: Gonzalez, T.
       title: Influence of COVID-19 confinement on students’ performance in higher education
        date: 2020-10-09
       words: 8521
      flesch: 57
     summary: Most probably, different students will find different motivations in this new scenario (probably a combination of many). In this subject we have expressed student performance as a 0-10 score and analyzed it across all tests performed in self-evaluation.
    keywords: assessment; confinement; covid-19; learning; performance; stage; students; study; tests; years
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        item: #4808 of 7819
          id: cord-316058-eh4m5jqz
      author: Long, Li
       title: Short-term Outcomes of Coronavirus Disease 2019 and Risk Factors for Progression
        date: 2020-04-20
       words: 1564
      flesch: 48
     summary: Moderate cases were defined when patients presented with fever and/or respiratory symptoms and have a radiographic appearance of pneumonia. As far as we know, this is the first study that focuses on clinical outcomes of COVID-19 patients rated as different severities on admission.
    keywords: cases; covid-19; patients; progression
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        item: #4809 of 7819
          id: cord-316063-9bg2dm8e
      author: Morgan, Marcus
       title: Why meaning-making matters: the case of the UK Government’s COVID-19 response
        date: 2020-10-15
       words: 25750
      flesch: 46
     summary: Government actions had failed to conform with the genre under which they were narrativizing the crisis, revealing a de-fused performance that wreaked havoc on the coherence of their drama. It Was Like a Fever: Storytelling in Protest and Politics Conjectures and refutations: The growth of scientific knowledge Liverpool v Atlético virus links 'interesting hypothesis', says government scientist.
    keywords: action; british; coronavirus; covid-19; crisis; cummings; day; death; disease; drama; events; genre; government; guardian; health; home; johnson; life; lockdown; march; meaning; mimetic; narrative; nhs; period; public; response; ritual; time; turner; virus; war; way; workers
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        item: #4810 of 7819
          id: cord-316065-fn64o0id
      author: Kotian, Rahul P
       title: Knowledge and understanding among medical imaging professionals in India during the rapid rise of the covid-19 pandemic
        date: 2020-05-25
       words: 2793
      flesch: 46
     summary: The finding of a high correct rate of COVID-19 knowledge in MIPs was unexpected, because this epidemiological survey was conducted during the very early stage-II of the pandemic. The levels of education and COVID-19 knowledge scores supports this speculation.
    keywords: covid-19; imaging; knowledge; mips; respondents; study
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        item: #4811 of 7819
          id: cord-316067-mlcczr8c
      author: Ng, Jia H.
       title: Outcomes of patients with end-stage kidney disease hospitalized with COVID-19
        date: 2020-08-15
       words: 4311
      flesch: 43
     summary: Impact of age, race and ethnicity on dialysis patient survival and kidney transplantation disparities Causes of death in dialysis patients: J o u r n a l P r e -p r o o f racial and gender differences Rate of ESRD exceeds mortality among African Americans with hypertensive nephrosclerosis Association of inflammatory markers with the severity of COVID-19: This inherent survival advantage may partly explain our finding of improved hospital survival of Black ESKD patients with COVID-19.
    keywords: covid-19; death; dialysis; eskd; hospital; mortality; patients; risk
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        item: #4812 of 7819
          id: cord-316080-y6ypbdtu
      author: Fajnzylber, J. M.
       title: SARS-CoV-2 Viral Load is Associated with Increased Disease Severity and Mortality
        date: 2020-07-17
       words: 1702
      flesch: 40
     summary: In contrast to prior reports suggesting that the SARS-CoV-2 viral infection is largely Additional studies of plasma viral load dynamics early in the course of disease are needed. https://doi.org/10.1101/2020.07.15.20131789 doi: medRxiv preprint Viral replication in the nasopharynx is associated with diarrhea in patients 317 with severe acute respiratory syndrome Viral loads in clinical specimens and SARS manifestations Temporal profiles of viral load in posterior oropharyngeal saliva samples and 321 serum antibody responses during infection by SARS-CoV-2: an observational cohort study Factors associated with prolonged viral RNA shedding in patients with COVID-19 Temporal dynamics in viral shedding and transmissibility of COVID-19 Estimating clinical severity of COVID-19 from the transmission dynamics in 328 Clinical Characteristics of Coronavirus Disease 2019 in China Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in 339 Endothelial cell infection and endotheliitis in COVID-19 Complex Immune Dysregulation in COVID-19 Patients with 343 Severe Respiratory Failure Detectable serum SARS-CoV-2 viral load (RNAaemia) is closely correlated with 345 drastically elevated interleukin 6 (IL-6) level in critically ill COVID-19 patients Detection of SARS-CoV-2 in Different Types of Clinical Specimens Virological assessment of hospitalized patients with COVID-2019 Prognosis in HIV-1 infection predicted by the quantity of virus in plasma HIV viral load markers in clinical practice Correlation of pandemic (H1N1) 2009 viral load with disease severity and 361 prolonged viral shedding in children Viral loads and duration of viral shedding in adult patients hospitalized with 364 influenza Detection of SARS coronavirus in plasma by real-time RT-PCR Detection of severe acute respiratory syndrome coronavirus RNA in plasma 368 during the course of infection Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-371 19 Tissue distribution of ACE2 protein, the functional receptor for SARS 373 coronavirus.
    keywords: medrxiv; plasma; preprint; sars
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        item: #4813 of 7819
          id: cord-316095-jzyb4jn5
      author: Falahchai, Mehran
       title: Dental care management during the COVID‐19 outbreak
        date: 2020-09-19
       words: 5607
      flesch: 46
     summary: During the COVID-19 pandemic, digital dentistry can greatly help in emergency management of dental patients whose temporary restorations are lost. Person-to-person transmission is very common among the family members and also healthcare workers who are in direct contact with COVID-19 patients and carriers.
    keywords: care; coronavirus; covid-19; dental; emergency; infection; patients; procedures; room; transmission; treatment; use
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        item: #4814 of 7819
          id: cord-316100-15zj660u
      author: Issitt, R.
       title: Coronavirus (COVID-19) infection in children at a specialist centre: outcome and implications of underlying high-risk comorbidities in a paediatric population
        date: 2020-05-25
       words: 4237
      flesch: 42
     summary: These data suggest that, whilst in children COVID-19 may occasionally present as severe disease, it does not appear to be had an adverse clinical course compared to other causes of similar presentation. There was a significantly reduced proportion of vulnerable cases (47.7% vs 72.3%, p=0.002), but no difference in proportion of vulnerable patients requiring ventilation (61% vs 64.3%, p = 0.84) between CoVPos and CoVNeg groups.
    keywords: author; covid-19; funder; medrxiv; patients; perpetuity; preprint
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        item: #4815 of 7819
          id: cord-316117-o29773cz
      author: Menzella, Francesco
       title: Pharmacologicaltreatment of COVID-19: lights and shadows
        date: 2020-05-19
       words: 4471
      flesch: 38
     summary: Specifically, a cytokine profile resembling MAS has been noted in COVID-19 patients, with increased interleukin (IL)-1β, IL-2, IL-6, IL-17, IL-8, tumor necrosis factor, and C-C motif chemokine ligand 2. 12 Current recommendations for the treatment of COVID-19 severe cases consist of using existing, approved therapies with proven safety profiles to address the immediate need to reduce the rising mortality. Fighting viruses with antibiotics: an overlooked path Teicoplanin potently blocks the cell entry of 2019-nCoV Coagulopathy and antiphospholipid antibodies in patients with Covid-19 Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Renin-angiotensin system blockers and the COVID-19 pandemic: at present there is no evidence to abandon renin-angiotensin system blockers Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Preliminary identification of potential vaccine targets for the COVID-19 coronavirus (SARS-CoV-2) based on SARS-CoV immunological studies A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice A live, impaired-fidelity coronavirus vaccine protects in an aged, immunocompromised mouse model of lethal disease Lack of peripheral memory B cell responses in recovered patients with severe acute respiratory syndrome: a six-year follow-up study Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection A sequence homology and bioinformatic approach can predict candidate targets for immune responses to SARS-CoV-2 Johnson Announces a Lead Vaccine Candidate for COVID-19 Department of Health & Human Services; and Commitment to Supply One Billion Vaccines Worldwide for Emergency Pandemic Use Roadmap to developing a recombinant coronavirus S protein receptor-binding domain vaccine for severe acute respiratory syndrome Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice Optimization of the production process and characterization of the yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1), a SARS vaccine candidate Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate.
    keywords: coronavirus; cov-2; covid-19; drugs; efficacy; infection; patients; pneumonia; remdesivir; sars; syndrome; treatment
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        item: #4816 of 7819
          id: cord-316118-ph582weg
      author: Frajkova, Zofia
       title: Postintubation Dysphagia During COVID-19 Outbreak-Contemporary Review
        date: 2020-05-28
       words: 5106
      flesch: 36
     summary: The aim of this review is to summarize available information on possible mechanisms of postintubation dysphagia in COVID-19 patients. Recommendations regarding the diagnosis and management of postintubation dysphagia in COVID-19 patients are described in this contemporary review.
    keywords: aspiration; covid-19; dysphagia; intubation; oral; patients; postintubation; risk; screening; swallowing
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        item: #4817 of 7819
          id: cord-316126-j51dik7f
      author: Zhang, X. Sophie
       title: SARS-CoV-2 and Health Care Worker Protection in Low-Risk Settings: a Review of Modes of Transmission and a Novel Airborne Model Involving Inhalable Particles
        date: 2020-10-28
       words: 12443
      flesch: 29
     summary: Recently, the WHO has acknowledged that short-range aerosol transmission, particularly in specific indoor locations, such as crowded and inadequately ventilated spaces over a prolonged period of time with infected persons cannot be ruled out but specifies that the significance of COVID-19 airborne transmission has not been convincingly demonstrated and requires further research (1) . World Health Organization Evidence of airborne transmission of the severe acute respiratory syndrome virus Environmental transmission of SARS at Amoy Gardens Cluster of SARS among medical students exposed to single patient Detection of airborne severe acute respiratory syndrome (SARS) coronavirus and environmental contamination in SARS outbreak units Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS) SARS among critical care nurses Intubation of SARS patients: infection and perspectives of healthcare workers Illness in intensive care staff after brief exposure to severe acute respiratory syndrome Lack of SARS transmission among healthcare workers, United States Lack of SARS transmission among public hospital workers SARS-CoV-2 in environmental samples of quarantined households Relative contributions of transmission routes for COVID-19 among healthcare personnel providing patient care Aerosol and surface contamination of SARS-CoV-2 observed in quarantine and isolation care Investigating SARS-CoV-2 surface and air contamination in an acute healthcare setting during the peak of the COVID-19 pandemic in London Environmental and aerosolized SARS-CoV-2 among hospitalized COVID-19 patients 2020.
    keywords: aerosols; airborne; care; contact; control; coronavirus; cov-2; covid-19; hcws; health; health care; infection; masks; particles; patients; protection; respirators; review; risk; sars; settings; studies; transmission; workers
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        item: #4818 of 7819
          id: cord-316135-kevyw19w
      author: Nikoupour, Hamed
       title: Pediatric liver transplantation and COVID-19: a case report
        date: 2020-10-06
       words: 1662
      flesch: 47
     summary: For pediatric patients with organ transplantations, extreme caution should be taken, to limit and prevent their contact with COVID-19 during the outbreak, as these patients are highly susceptible to severe forms of the disease. [5] reported in-hospital infection rates in a large series of pediatric patients to be 9.4%, moreover infections constituted 35.2% of all causes of death in this population.
    keywords: covid-19; liver; patient; pediatric
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        item: #4819 of 7819
          id: cord-316137-6zdxfv8v
      author: Wang, Yuanyuan
       title: Effect and safety of Chinese herbal medicine granules in patients with severe coronavirus disease 2019 in Wuhan, China: a retrospective, single-center study with propensity score matching
        date: 2020-11-05
       words: 4552
      flesch: 49
     summary: Of these, 22% of severe patients and up to 78% of critically ill patients had death as the outcome. The National Health Commission of the People's Republic of China (2020a, 2020b) recommended the traditional Chinese medicine (TCM), which has a long history in treating influenza-like diseases and proven to be effective in treating severe acute respiratory syndrome (SARS) epidemic in 2003 (Chen and Nakamura, 2004; Lau et al., 2005; Leung, 2007) , to be used jointly with modern treatment for COVID-19 patients.
    keywords: care; china; chm; clinical; covid-19; day; disease; granules; group; patients; study
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        item: #4820 of 7819
          id: cord-316157-7nci4q1q
      author: Iheduru‐Anderson, Kechi
       title: Reflections on the lived experience of working with limited personal protective equipment during the COVID‐19 crisis
        date: 2020-10-03
       words: 6117
      flesch: 49
     summary: This study used a descriptive phenomenological design to describe the lived experience of acute care nurses working with limited access to PPE during the COVID‐19 pandemic. The purpose of this study was to describe the lived experience of acute care nurses working with limited access to PPE during the COVID-19 pandemic.
    keywords: care; covid-19; crisis; experiences; health; nurses; participants; patients; ppe; study; work
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        item: #4821 of 7819
          id: cord-316186-254z62e4
      author: Kario, Kazuomi
       title: COVID‐19 and hypertension—evidence and practical management: Guidance from the HOPE Asia Network
        date: 2020-07-09
       words: 3318
      flesch: 29
     summary: Coronavirus disease 2019 (COVID-19) information for cardiologists -systematic literature review and additional analysis Renin-angiotensin-aldosterone system inhibitors in patients with Covid-19 The global epidemiology of hypertension Heart disease and stroke statistics-2015 update: a report from the American Heart Association The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019) Primary prevention of hypertension: clinical and public health advisory from The National High Blood Pressure Education Program ESC/ESH Guidelines for the management of arterial hypertension Consensus summary on the management of hypertension in Asia from the HOPE Asia Network Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants The HOPE Asia Network activity for zero cardiovascular events in Asia: overview 2020 Diversity of and initiatives for hypertension management in Asia-Why we need the HOPE Asia Network Characteristics of COVID-19 patients dying in Italy Coronavirus disease 2019 (COVID-19) and cardiovascular disease Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 Pneumonia in Wuhan, China Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2 Endothelial cell infection and endotheliitis in COVID-19 Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein Role of the ACE2/ Angiotensin 1-7 axis of the Renin-Angiotensin system in heart failure Angiotensin converting enzyme 2: a double-edged sword Oral delivery of Angiotensin-converting enzyme 2 and Angiotensin-(1-7) bioencapsulated in plant cells attenuates pulmonary hypertension Roles of angiotensin peptides and recombinant human ACE2 in heart failure ACE2 and ADAM17 interaction regulates the activity of presympathetic neurons The angiotensin-(1-7)/mas axis counteracts angiotensin II-dependent and -independent pro-inflammatory signaling in human vascular smooth muscle cells New physiological concepts of the renin-angiotensin system from the investigation of precursors and products of angiotensin I metabolism Therapeutic implications of the vasoprotective axis of the renin-angiotensin system in cardiovascular diseases A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury AT1 receptor signaling pathways in the cardiovascular system ADAM17: a molecular switch to control inflammation and tissue regeneration Structure, regulation and function of NF-kappa B COVID-19: a new virus, but a familiar receptor and cytokine release syndrome Upregulation of angiotensin-converting enzyme 2 after myocardial infarction by blockade of angiotensin II receptors Renin-angiotensin-aldosterone system blockers and the risk of Covid-19 Association of use of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers with testing positive for coronavirus disease Renin-angiotensin-aldosterone system inhibitors and risk of Covid-19 Association of renin-angiotensin system inhibitors with severity or risk of death in patients with hypertension hospitalized for coronavirus disease 2019 (COVID-19) infection in Wuhan, China Effects of ARBs and ACEIs on virus infection, inflammatory status and clinical outcomes in COVID-19 patients with hypertension: a single center retrospective study Association of inpatient use of angiotensin converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19 The impact of 2019 novel coronavirus on heart injury: a systemic review and meta-analysis Sanchis-Gomar F. Cardiac troponin I in patients with coronavirus disease 2019 (COVID-19): evidence from a meta-analysis Clinical features of patients infected with 2019 novel coronavirus in Wuhan Use of D-dimer in oral anticoagulation therapy D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19 Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Prevention and treatment of venous thromboembolism associated with coronavirus disease 2019 infection: a consensus statement before guidelines The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team.
    keywords: angiotensin; asia; covid-19; disease; hypertension; inhibitors; management; patients; risk
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        item: #4822 of 7819
          id: cord-316197-r2ctm5sl
      author: Abbaszadeh-Kasbi, Ali
       title: An Invited Commentary on Impact of the Coronavirus (COVID-19) pandemic on surgical practice- -Part 1
        date: 2020-06-02
       words: 499
      flesch: 43
     summary: As this paper has reviewed the comprehensive protocols for resuming non-urgent surgeries, a detail and specialized protocol should be developed for each hospital for resuming non-urgent surgeries after passing COVID-19 peak. International journal of surgery Impact of the COVID-19 pandemic on surgical services: early experiences at a nominated COVID-19 centre
    keywords: covid-19; pandemic
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        item: #4823 of 7819
          id: cord-316209-juvmabdq
      author: Rutayisire, Erigene
       title: What works and what does not work in response to COVID-19 prevention and control in Africa
        date: 2020-06-12
       words: 2337
      flesch: 46
     summary: Since the last brief on May 26 th from Africa CDC, the number of COVID-19 cases has increased by 32% (37096 cases), this shows the burden COVID-19 could impose on African countries. If the cases continue to increase, many African countries will not be able to manage those cases; there is a need for international cooperation to reduce the burden this disease will impose on African countries.
    keywords: africa; cases; countries; covid-19; health; measures
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        item: #4824 of 7819
          id: cord-316260-1t3ifsfi
      author: Nogueira-de-Almeida, Carlos Alberto
       title: COVID-19 and obesity in childhood and adolescence: A clinical review()()
        date: 2020-08-04
       words: 7977
      flesch: 33
     summary: key: cord-316260-1t3ifsfi authors: Nogueira-de-Almeida, Carlos Alberto; Ciampo, Luiz A. Del; Ferraz, Ivan S.; Ciampo, Ieda R.L. Del; Contini, Andrea A.; Ued, Fábio da V. title: COVID-19 and obesity in childhood and adolescence: A clinical review()() date: 2020-08-04 journal: J Pediatr (Rio J) DOI: 10.1016/j.jped.2020.07.001 sha: doc_id: 316260 cord_uid: 1t3ifsfi OBJECTIVE: To identify factors that contribute to the increased susceptibility and severity of COVID-19 in obese children and adolescents, and its health consequences. Facing children with suspected or confirmed COVID-19, health professionals should 1) diagnose excess weight; 2) advise on health care in times of isolation; 3) screen for comorbidities, ensuring that treatment is not interrupted; 4) measure levels of immunonutrients; 5) guide the family in understanding the specifics of the situation; and 6) refer to units qualified to care for obese children and adolescents when necessary.
    keywords: adolescents; age; care; cells; childhood; children; coronavirus; cov-2; covid-19; disease; infection; inflammatory; obese; obesity; patients; response; review; risk; sars
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        item: #4825 of 7819
          id: cord-316325-uqrlza4k
      author: Jardim, L.
       title: The effective reproductive number (Rt) of COVID-19 and its relationship with social distancing
        date: 2020-07-29
       words: 2936
      flesch: 34
     summary: Considering the amount of variation explained and the randomness of the residuals of the relationship between isolation and Rt, we understand that using isolation indicators obtained from mobile phones can be a good surrogate for COVID-19 transmission in a given population, and can be used for modeling purposes as well as routine epidemiological analyses. https://doi.org/10.1101/2020.07.28.20163493 doi: medRxiv preprint Modeling the pandemic Predictive Mathematical Models of the COVID-19 Pandemic: Underlying Principles and Value of Projections Unraveling R0: considerations for public health applications The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application Temporal dynamics in viral shedding and transmissibility of COVID-19 Association between mobility patters and COVID-19 transmission in the USA: a mathematical modelling study Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe Estimating the time-varying reproduction number of SARS-CoV-2 using national and subnational case counts The lockdowns worked-but what comes next?
    keywords: covid-19; isolation; license; medrxiv; preprint
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        item: #4826 of 7819
          id: cord-316327-0hpthrjo
      author: Brar, Branden
       title: A Survey Assessing the Early Effects of COVID-19 Pandemic on Oral & Maxillofacial Surgery Training Programs
        date: 2020-08-18
       words: 4500
      flesch: 37
     summary: OMFS training programs should give more consideration to provide residents with adequate stress reduction resources to maintain their wellbeing and training to minimize exposure risk during an evolving global epidemic. OMFS training programs should give more consideration to provide residents with adequate stress reduction resources to maintain their wellbeing and training to minimize exposure risk during an evolving global epidemic.
    keywords: care; covid-19; emergency; omfs; pandemic; ppe; procedures; programs; survey; training
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        item: #4827 of 7819
          id: cord-316345-a1cirnya
      author: Comas, Carmina
       title: COVID‐19 and pregnancy: An opportunity to correct an historic gender bias
        date: 2020-08-02
       words: 1451
      flesch: 33
     summary: COVID-19 infection in pregnant women creates additional challenges, for different reasons. jmv.26350 sha: doc_id: 316345 cord_uid: a1cirnya Current literature and clinical guidelines do not include pregnant women as an a priori risk group for COVID‐19.
    keywords: covid-19; infection; pregnancy; women
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        item: #4828 of 7819
          id: cord-316354-pix0hmpj
      author: Kennedy, Nicholas A
       title: Organisational changes and challenges for inflammatory bowel disease services in the UK during the COVID-19 pandemic
        date: 2020-06-15
       words: 5237
      flesch: 45
     summary: Frontline Gastroenterol DOI: 10.1136/flgastro-2020-101520 sha: doc_id: 316354 cord_uid: pix0hmpj OBJECTIVE: To determine the challenges in diagnosis, monitoring, support provision in the management of inflammatory bowel disease (IBD) patients and explore the adaptations of IBD services. METHODS: Internet-based survey by invitation of IBD services across the UK from 8 to 14 April 2020.
    keywords: bowel; care; covid-19; disease; face; ibd; pandemic; patients; services; survey
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        item: #4829 of 7819
          id: cord-316363-7eh9k442
      author: Adams, Scott J
       title: Telerobotic ultrasound to provide obstetrical ultrasound services remotely during the COVID-19 pandemic
        date: 2020-10-20
       words: 5019
      flesch: 27
     summary: Patients were scheduled for telerobotic ultrasound exams based on clinical urgency indicated on the requisition. No adverse events related to telerobotic ultrasound exams were reported.
    keywords: care; covid-19; exams; health; pandemic; patients; study; system; trimester; ultrasound
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        item: #4830 of 7819
          id: cord-316370-t802kjpk
      author: Szperka, Christina L.
       title: Migraine Care in the Era of COVID‐19: Clinical Pearls and Plea to Insurers
        date: 2020-04-03
       words: 4043
      flesch: 41
     summary: A randomized clinical trial Eptinezumab for prevention of chronic migraine: A randomized phase 2b clinical trial Eptinezumab in episodic migraine: A randomized, double-blind, placebo-controlled study (PROMISE-1) Prophylactic treatment of migraine with angiotensin converting enzyme inhibitor (lisinopril): Randomised, placebo controlled, crossover study Prophylactic treatment of migraine with an angiotensin II receptor blocker: A randomized controlled trial ACE and ARB agents in the prophylactic therapy of migraine-how effective are they? Efficacy of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in the preventative treatment of episodic migraine in adults Efficacy of lisinopril in migraine prophylaxis -An open label study HFSA/ACC/ AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19 Randomised clinical trial comparing melatonin 3 mg, amitriptyline 25 mg and placebo for migraine prevention Use of melatonin versus valproic acid in prophylaxis of migraine patients: A double-blind randomized clinical trial. Further, given that nearly 1/5 of households in the United States reported a layoff or reduction in work hours related to coronavirus by March 14, 2020, 3 it is imperative that insurance providers minimize or eliminate copays for migraine medications.
    keywords: acute; care; covid-19; days; headache; migraine; patients; treatment; trial
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        item: #4831 of 7819
          id: cord-316376-76beuk0c
      author: Medeiros, Augusto Kreling
       title: Higher frequency of hepatic steatosis at CT among COVID-19-positive patients
        date: 2020-07-18
       words: 4132
      flesch: 36
     summary: Major strengths include the fact that this is the first study to compare steatosis on CT between positive and negative COVID-19 patients; the sample size, which has allowed statistical power to identify the higher frequency of liver steatosis among SARS-CoV2 positive patients; finally, as CT studies were performed on the same scanner (to avoid exposure of patients without flu syndrome), with a variable protocol according to their body habitus, inter-scanner variability that could have affected measurements did not compromise the results, allowing uniformity. These findings are in accordance with other recent studies linking obesity and COVID-19 infection, as there is an intricate relationship between liver steatosis, metabolic syndrome and obesity.
    keywords: covid-19; disease; group; liver; obesity; patients; steatosis; study
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        item: #4832 of 7819
          id: cord-316395-o9nblj5i
      author: Pizzini, Alex
       title: Impact of Vitamin D Deficiency on COVID-19—A Prospective Analysis from the CovILD Registry
        date: 2020-09-11
       words: 3444
      flesch: 33
     summary: VITD deficiency is frequent among COVID-19 patients but not associated with disease outcomes. Herein, we report results of the ongoing prospective multicenter observational CovILD study (ClinicalTrials.gov number, NCT04416100), aiming to evaluate the persistent cardio-pulmonary damage of COVID-19 patients.
    keywords: 25(oh)d; covid-19; deficiency; disease; patients; study; treatment; vitamin; vitd
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        item: #4833 of 7819
          id: cord-316402-6u1czbfe
      author: Knowles, Kelly A.
       title: Anxiety and Safety Behavior Usage During the COVID-19 Pandemic: The Prospective Role of Contamination Fear
        date: 2020-10-20
       words: 4283
      flesch: 41
     summary: First, paired comparisons t-tests were used to compare coronavirus-related anxiety and influenza-related anxiety, as well as coronavirus safety behaviors and influenza safety behaviors. Baseline washing symptoms did not significantly predict coronavirus safety behaviors, r(104) = .15, p = .11.
    keywords: anxiety; behaviors; contamination; coronavirus; covid-19; fear; safety
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        item: #4834 of 7819
          id: cord-316422-wmkv5hd3
      author: Eisenberg, Matthew D.
       title: Financial Risk for COVID-19-like Respiratory Hospitalizations in Consumer-Directed Health Plans
        date: 2020-06-15
       words: 1709
      flesch: 39
     summary: It compared unadjusted out-of-pocket spending among consumer-directed health plan enrollees to traditional plan enrollees using difference of mean significance tests and repeated the analysis separately by age category and by calendar year quarter. RESULTS: : Commercially insured consumer-directed health plan enrollees had significantly higher out-of-pocket spending than traditional plan enrollees and these differences were largest among younger populations.
    keywords: covid-19; enrollees; health; spending
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        item: #4835 of 7819
          id: cord-316432-xemz7zn9
      author: Talaie, Haleh
       title: Is there any potential management against COVID-19? A systematic review and meta-analysis
        date: 2020-08-18
       words: 5097
      flesch: 33
     summary: National Institutes of Health Drug-eluting stents versus bare metal stents for saphenous vein graft revascularisation: a meta-analysis of randomised trials Immunosuppressive drugs to reduce the mortality rate in patients with moderate to severe paraquat poisoning: a meta-analysis Legionella prevalence and risk of legionellosis in Japanese households Quantifying heterogeneity in a metaanalysis Bioaccumulation of potentially toxic elements (PTEs) in muscleTilapiaspp fish: a systematic review, meta-analysis, and non-carcinogenic risk assessment Toxocara eggs in public places worldwide-a systematic review and meta-analysis The global seroprevalence of toxoplasma gondii in pigs: a systematic review and meta-analysis The global seroprevalence of toxoplasma DARU J Pharm Sci gondii among wild boars: a systematic review and meta-analysis Seroprevalence estimates for toxocariasis in people worldwide: A systematic review and meta-analysis Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial Lopinavir-ritonavir versus hydroxychloroquine for viral clearance and clinical improvement in patients with mild to moderate coronavirus disease 2019 Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study Association of treatment with hydroxychloroquine or azithromycin with in-hospital mortality in patients with COVID-19 in New York state Full-length title: Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France Lack of viral clearance by the combination of hydroxychloroquine and azithromycin or lopinavir and ritonavir in SARS-CoV-2-related acute respiratory distress syndrome Treatment Response to Hydroxychloroquine, Lopinavir/Ritonavir, and Antibiotics for Moderate COVID 19: A First Report Pharmacol Outcomes South Korea. medRxiv Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19: a randomized clinical trial Treatment of 5 critically ill patients with COVID-19 with convalescent plasma Treatment with convalescent plasma for COVID-19 patients in Wuhan Treatment of Coronavirus Disease 2019 (COVID-19) Patients with Convalescent Plasma Mortality reduction in 46 severe Covid-19 patients treated with hyperimmune plasma.
    keywords: analysis; coronavirus; covid-19; meta; mortality; patients; plasma; review; studies; study; therapy; treatment
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        item: #4836 of 7819
          id: cord-316440-xt9tl7td
      author: Severo, Eliana Andrea
       title: Impact of the COVID-19 Pandemic on environmental awareness, sustainable consumption and social responsibility: evidence from generations in Brazil and Portugal
        date: 2020-11-05
       words: 6352
      flesch: 30
     summary: Another important element is air pollution, according to Zambrano-Monserrate et al. (2020), there is a significant association between COVID-19 Pandemic contingency measures and the improvement of air quality, clean beaches and reduction of environmental noise. In this scenario, the study by Bashir et al. (2020) indicates that environmental pollutants such as PM 10 , PM 2.5 , SO 2 , NO 2 and CO have a significant correlation with the COVID-19 epidemic in California, just as it becomes relevant to encourage regulators to promote changes in environmental policies, because controlling the source of pollution can reduce the harmful effects of environmental pollutants.
    keywords: consumption; covid-19; covid-19 pandemic; effect; et al; generations; health; impact; pandemic; people; relationships; research; responsibility; table
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        item: #4837 of 7819
          id: cord-316450-iw35sorz
      author: Gunjawate, Dhanshree R.
       title: Impact of coronavirus disease 2019 on professional practices of audiologists and speech-language pathologists in India: A knowledge, attitude and practices survey
        date: 2020-08-08
       words: 3077
      flesch: 51
     summary: Next, 'COVID-19 infection can spread through small droplets from nose or mouth of infected person' was a true statement. The ideal distance to be maintained from a person with COVID-19 infection is 3 feet.
    keywords: covid-19; hand; infection; professionals; speech; study
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        item: #4838 of 7819
          id: cord-316484-2s8w7r4v
      author: Arias-Reyes, C.
       title: Decreased incidence, virus transmission capacity, and severity of COVID-19 at altitude on the American continent
        date: 2020-07-24
       words: 5361
      flesch: 46
     summary: Furthermore, considering that various factors, such as public health policies, diagnostic strategies, confinement rules, and cultural aspects, may influence the number of reported cases of COVID-19, we performed a randomized block design ANOVA test to compare the number of COVID-19 cases (normalized, logarithmized, and organized by intervals of 100 meters of altitude) above and below 1,000 m. Moreover, independent examination from all the American countries that reported cases at more than 1,000 masl (14 out of 23) confirmed this result, except for four nations: Bolivia, in which the low number of cases reported for moderate-altitude regions (1,000 -2,500 masl) masked a possible correlation; Chile, in which its long and narrow geography (flanked by the Andean mountains on the east and the Pacific Ocean) does not allow obtaining precise altitude values for COVID-19 cases; and Dominican Republic, Haiti and Panamá, in which the highest altitude with reported cases is just over 1,000 masl.
    keywords: altitude; cases; countries; covid-19; data; highlands; july; masl; medrxiv; number; preprint; rate
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        item: #4839 of 7819
          id: cord-316485-t6xfjqkb
      author: Cohn-Schwartz, Ella
       title: Societal views of older adults as vulnerable and a burden to society during the COVID-19 outbreak: Results from an Israeli nationally representative sample
        date: 2020-09-03
       words: 2473
      flesch: 56
     summary: As older adults remind us of our own mortality, we attempt to distance ourselves from them and might hold more ageist attitudes towards older people to protect ourselves from the discomfort involving frailty and sickness associated with older age (Lev et al., 2018) . key: cord-316485-t6xfjqkb authors: Cohn-Schwartz, Ella; Ayalon, Liat title: Societal views of older adults as vulnerable and a burden to society during the COVID-19 outbreak: Results from an Israeli nationally representative sample date: 2020-09-03 journal: J Gerontol B Psychol Sci Soc Sci DOI: 10.1093/geronb/gbaa150 sha: doc_id: 316485 cord_uid: t6xfjqkb OBJECTIVES:
    keywords: adults; age
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        item: #4840 of 7819
          id: cord-316501-fl2wvhia
      author: Noh, Ji Yun
       title: Asymptomatic infection and atypical manifestations of COVID-19: comparison of viral shedding duration
        date: 2020-05-21
       words: 446
      flesch: 40
     summary: key: cord-316501-fl2wvhia authors: Noh, Ji Yun; Yoon, Jin Gu; Seong, Hye; Choi, Won Suk; Sohn, Jang Wook; Cheong, Hee Jin; Kim, Woo Joo; Song, Joon Young title: Asymptomatic infection and atypical manifestations of COVID-19: comparison of viral shedding duration date: 2020-05-21 journal: J Infect DOI: 10.1016/j.jinf.2020.05.035 sha: doc_id: 316501 cord_uid: fl2wvhia • More than 25% of patients with COVID-19 were asymptomatic. Irrespective of clinical manifestations, all patients with COVID-19 showed prolonged viral shedding. to evaluate the prevalence of asymptomatic infection, anosmia (smell loss) and ageusia (taste 8 loss) among patients with mild COVID-19 in a residential treatment center (RTC).
    keywords: covid-19; patients
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        item: #4841 of 7819
          id: cord-316522-fbw9x3ik
      author: Reiss, Allison B.
       title: A Telemedicine Approach to Covid-19 Assessment and Triage
        date: 2020-09-10
       words: 3800
      flesch: 47
     summary: The most common laboratory abnormality in Covid-19 patients is lymphopenia, with decrease in lymphocyte count more profound in severe cases [60, 61] . The most common laboratory abnormality in Covid-19 patients is lymphopenia, with decrease in lymphocyte count more profound in severe cases [60, 61] .
    keywords: coronavirus; covid-19; disease; infection; patients; risk; screening; telemedicine; visit
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        item: #4842 of 7819
          id: cord-316543-1tb2tkis
      author: Urooj, Uzma
       title: Expectations, Fears and Perceptions of doctors during Covid-19 Pandemic
        date: 2020-05-17
       words: 2612
      flesch: 55
     summary: MVSC Malta-mobidoctor Mobile field hospitals, an effective way of dealing with COVID-19 in China: sharing our experience Factors associated with mental health outcomes among health care workers exposed to Coronavirus disease 2019 Unintended consequences of COVID-19 A novel coronavirus emerging in Chinakey questions for impact assessment COVID-19 is an emerging, rapidly evolving situation Impact on Mental Health and Perceptions of Psychological Care among Medical and Nursing Staff in Wuhan during the 2019 Novel Coronavirus Disease Outbreak: A cross-sectional study Influence of Community and Culture in the Ethical Allocation of Scarce Medical Resources in a Pandemic Situation: Deliberative Democracy Study Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (COVID-19) epidemic among the general population in china A systematic review of the impact of disaster on the mental health of medical responders COVID-19: what is next for public health? Rapid Response to COVID-19: Health Informatics Support for Outbreak Management in an Academic Health System Maximizing the Calm Before the Storm: Tiered Surgical Response Plan for Novel Coronavirus Supporting Clinicians During the COVID-19 Pandemic Psychological Impact and Coping Strategies of Frontline Medical Staff in Hunan Between World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19) Assistant Professor, Department of Gynae/Obs, NUMS, 2. Asma Ansari, MBBS, FCPS. The study included 150(67.5%) Female and 72(32.4%)
    keywords: covid-19; doctors; expectations; health; pandemic; study
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        item: #4843 of 7819
          id: cord-316572-7ei96rrn
      author: Touska, P
       title: The role of transoral fine needle aspiration in expediting diagnosis and reducing risk in head and neck cancer patients in the coronavirus disease 2019 (COVID-19) era: a single-institution experience
        date: 2020-09-02
       words: 3267
      flesch: 33
     summary: Transoral fine needle aspiration cytology offers a low-risk means of rapidly diagnosing patients with oral cavity or oropharyngeal lesions. Diagnostic outcomes were retrospectively evaluated for a series of patients undergoing transoral fine needle aspiration cytology of oral cavity and oropharyngeal lesions during the COVID-19 pandemic.
    keywords: covid-19; diagnosis; lesions; neck; needle; patients; transoral
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        item: #4844 of 7819
          id: cord-316579-p6pz14eo
      author: Seheult, Jansen N.
       title: Fibrinolysis Shutdown and Thrombosis in Severe SARS-CoV-2 (COVID-19)
        date: 2020-06-12
       words: 1128
      flesch: 22
     summary: Incidence of venous thromboembolism in hospitalized patients with COVID-19 Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Association of treatment dose anticoagulation with in-hospital survival among hospitalized patients with COVID-19 Fibrinolysis shutdown correlates to thromboembolic events in severe COVID-19 Infection Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia 4 They described an elevated maximum amplitude (MA) in TEG analyses, consistent with a hypercoagulable state, and a low lysis at 30 minutes in 57% of patients, suggestive of fibrinolysis shutdown.
    keywords: covid-19; fibrinolysis; patients; shutdown
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        item: #4845 of 7819
          id: cord-316588-8els3rzj
      author: Habib, Mhd Baraa
       title: Acute symptomatic hyponatremia in setting of SIADH as an isolated presentation of COVID-19
        date: 2020-06-01
       words: 1484
      flesch: 48
     summary: A meta-analysis showed that the main clinical symptoms of COVID-19 patients were fever (88.5%), cough (68.6%), myalgia or fatigue (35.8%), expectoration (28.2%), and dyspnea (21.9%). The most common symptoms associated with COVID-19 infection are fever, congested nose, and cough; and may also cause severe pneumonia
    keywords: covid-19; hyponatremia; serum; siadh
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        item: #4846 of 7819
          id: cord-316616-j82q99in
      author: Su, Yen-Bo
       title: Cardiovascular manifestation and treatment in COVID-19
        date: 2020-05-19
       words: 4455
      flesch: 28
     summary: In addition, 71% of COVID-19 patients who died fulfilled the International Society on Thrombosis and Haemostasis (ISTH) criteria for DIC, compared with only 0.6% among survivors. 34 Gilead has initiated several trials in United States and China to evaluate the effect of remdesivir in COVID-19 patients with different disease severity (https://www.gilead.com/purpose/ advancing-global-health/covid-19/remdesivir-clinical-trials).
    keywords: cardiac; coronavirus; covid-19; disease; infection; injury; levels; mortality; patients; pneumonia; sars; treatment
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        item: #4847 of 7819
          id: cord-316617-8cqxz3wi
      author: Ward, Michael P.
       title: SARS‐CoV‐2, where to now?
        date: 2020-06-19
       words: 1240
      flesch: 36
     summary: Supporting pandemic response using genomics and bioinformatics: A case study on the emergent SARS-CoV-2 outbreak Preparedness for emerging infectious diseases: Pathways from anticipation to action Serological survey of SARS-CoV-2 for experimental, domestic, companion and wild animals excludes intermediate hosts of 35 different species of animals Recent progress on the diagnosis of 2019 Novel Coronavirus Cats under the shadow of the SARS-CoV-2 pandemic Explanation for COVID-19 infection neurological damage and reactivations High COVID-19 virus replication rates, the creation of antigen-antibody immune complexes, and indirect hemagglutination resulting in thrombosis One health surveillance: More than a buzz word? The COVID-19 pandemic could be a catalyst for such a seismic shift in how we approach emerging infectious diseases and One Health.
    keywords: cov-2; covid-19; health; sars
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        item: #4848 of 7819
          id: cord-316631-um0olqet
      author: Park, Kyung Chan
       title: Single‐cell oxygen saturation imaging shows that gas exchange by red blood cells is not impaired in COVID‐19 patients
        date: 2020-08-01
       words: 967
      flesch: 45
     summary: 12 We now applied this technique to study blood from COVID-19 patients at the John Radcliffe Hospital, Oxford, UK. RBC s, j and radius were no different in COVID-19 patients, compared to controls (Fig 1C-E) .
    keywords: blood; covid-19; infection; patients
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        item: #4849 of 7819
          id: cord-316632-rr9f88oi
      author: Kimura, Yurika
       title: Society of swallowing and dysphagia of Japan: Position statement on dysphagia management during the COVID-19 outbreak
        date: 2020-07-23
       words: 3101
      flesch: 46
     summary: Dysphagia treatment includes a broad range of clinical assessments and examinations, dysphagia rehabilitation, oral care, nursing care, and surgical treatments. Dyspha-15 gia treatment includes a broad range of clinical assessment 16 and examinations, dysphagia rehabilitation, oral care, nurs- 17 ing care, and surgical treatments, and any of these can lead 18 to the production of droplets and aerosols, as well as con- 19 tact with viral particles.
    keywords: care; cov-2; covid-19; dysphagia; infection; patients; ppe; swallowing
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        item: #4850 of 7819
          id: cord-316647-jj8anf5g
      author: Shang, You
       title: Management of critically ill patients with COVID-19 in ICU: statement from front-line intensive care experts in Wuhan, China
        date: 2020-06-06
       words: 13606
      flesch: 35
     summary: However, considering the suggestion that restrictive fluid volume management strategy should be adopted for COVID-19 patients complicated by ARDS based on the premise of sufficient tissue perfusion, we suggest CRRT initiation in severe patients within 24 h when they show rank 2 AKI under KDIGO criteria or accompanied with cytokine storm syndrome. There are still no targeted therapies for COVID-19 patients.
    keywords: acute; aki; ards; care; coronavirus; covid-19; covid-19 patients; disease; expert; grade; infection; lung; mortality; patients; rationale; recommendation; risk; sedation; study; syndrome; therapy; treatment; use; ventilation
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        item: #4851 of 7819
          id: cord-316654-tihbi0ak
      author: Tosti, G.
       title: Skin signs resembling vascular acrosyndromes during the COVID‐19 outbreak in Italy
        date: 2020-05-25
       words: 717
      flesch: 54
     summary: After three days, the lesions persisted and became hardened erythematous plaques. After 3 days, the lesions persisted and became hardened erythematous plaques.
    keywords: covid-19; patients
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        item: #4852 of 7819
          id: cord-316666-qif1k62t
      author: Ghati, Nirmal
       title: Atorvastatin and Aspirin as Adjuvant Therapy in Patients with SARS-CoV-2 Infection: A structured summary of a study protocol for a randomised controlled trial
        date: 2020-10-30
       words: 4405
      flesch: 39
     summary: Patients with early discharge (due to clinical improvement and patient's preference for home isolation) will be followed up by alternate day telephonic contact till 10 th day of drug regimen. The safety of these drugs in COVID-19 patients will also be evaluated.
    keywords: aspirin; atorvastatin; covid-19; days; disease; group; infection; patients; statins; study; therapy; trial
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        item: #4853 of 7819
          id: cord-316690-s8jtv4an
      author: Xiong, Huan
       title: The Psychological Status and Self-Efficacy of Nurses During COVID-19 Outbreak: A Cross-Sectional Survey
        date: 2020-09-08
       words: 3314
      flesch: 46
     summary: Epidemiological characteristics of novel coronavirus pneumonia Psychological impact of the COVID-19 pandemic on health care workers in Singapore A multinational, multicentre study on the psychological outcomes and associated physical symptoms amongst healthcare workers during COVID-19 outbreak Prevalence of psychiatric disorders among Toronto Hospital workers one to two years after the SARS outbreak Mental symptoms in different health professionals during the SARS attack: a follow-up study Psychosocial effects of SARS on hospital staff: survey of a large tertiary care institution Vicarious traumatization in the general public, members, and non-members of medical teams aiding in COVID-19 control Self-efficacy: toward a unifying theory of behavioral change Self-efficacy: The Exercise of Control Optimistic self-beliefs: assessment of general perceived self-efficacy in thirteen cultures The mediating role of self-efficacy in the relationship between workplace bullying, mental health and an intention to leave among nurses in Taiwan Personal and work-related factors associated with nurse resilience: a systematic review Selfefficacy, perceptions of context, and burnout: a multilevel study on nurses Assessment of perceived general self-efficacy on the internet: data collection in cyberspace The reliability and validity of general self-efficacy scale Fear of severe acute respiratory syndrome (SARS) among health care workers Factors influencing nurses' intention to care for patients with emerging infectious diseases: application of the theory of planned behavior Willingness of future nursing workforce to report for duty during an avian influenza pandemic A brief measure for assessing generalized anxiety disorder: the GAD-7 Evaluation of the reliability and validity of the generalized anxiety disorder 7-item scale among inpatients in general hospital The PHQ-9: validity of a brief depression severity measure Reliability and validity of the Chinese version of the Patient Health Questionnaire (PHQ-9) in the general population Measuring optimistic self-beliefs: a Chinese adaptation of the General Self-Efficacy Scale The current status and influencing factors on psychological stress of clinical nurse in the designated hospitals during the period of prevention and control of novel coronavirus pneumonia. key: cord-316690-s8jtv4an authors: Xiong, Huan; Yi, Shuanglian; Lin, Yufen title: The Psychological Status and Self-Efficacy of Nurses During COVID-19 Outbreak: A Cross-Sectional Survey date: 2020-09-08 journal: Inquiry DOI: 10.1177/0046958020957114 sha: doc_id: 316690 cord_uid: s8jtv4an A novel coronavirus pneumonia broke out and gradually developed into a global public health problem.
    keywords: anxiety; covid-19; depression; efficacy; nurses; self
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        item: #4854 of 7819
          id: cord-316691-8d1mmbac
      author: Owens, Andrew P.
       title: Implementing Remote Memory Clinics to Enhance Clinical Care During and After COVID-19
        date: 2020-09-18
       words: 8975
      flesch: 28
     summary: Diagnostic accuracy of tablet-based software for the detection of concussion Computerized cognitive assessment in primary care to identify patients with suspected cognitive impairment Applicability of the CANTAB-PAL computerized memory test in identifying amnestic mild cognitive impairment and alzheimer's disease Home-based computerized cognitive assessment tool for dementia screening Validation of a new mass screening tool for cognitive impairment: Cognitive assessment for Dementia, iPad version Contributions of the Computer-Administered Neuropsychological Screen for Mild Cognitive Impairment (CANS-MCI) for the diagnosis of MCI in Brazil Level of recall, retrieval speed, and variability on the Cued-Recall Retrieval Speed Task (CRRST) in individuals with amnestic mild cognitive impairment Evaluating the feasibility of frequent cognitive assessment using the Mezurio smartphone app: Observational and interview study in adults with elevated dementia risk A mobile application for cognitive screening of dementia Evaluation of multidimensional neurocognitive function using a tablet personal computer: Test-retest reliability and validity in communitydwelling older adults Engagement with a digital platform for multimodal cognitive assessment and multidomain intervention in a Japanese population: Pilot, quasi-experimental, longitudinal study Computerized spatial delayed recognition span task: A specific tool to assess visuospatial working memory Early identification of cognitive impairment and dementia: Results from four years of the community consultation center Wearable technology for high-frequency cognitive and mood assessment in major depressive disorder: Longitudinal observational study Digital technologies as biomarkers, clinical outcomes assessment, and recruitment tools in Alzheimer's disease clinical trials A Preliminary Study on the Feasibility of&nbsp;Using a Virtual Reality Cognitive Training Application for Remote Detection of Mild Cognitive Impairment Day-to-day variability of postural sway and its association with cognitive function in older adults: A pilot study Comparing the Electronic and Standard Versions of the Montreal Cognitive Assessment in an Outpatient Memory Disorders Clinic: A Validation Study Sensitivity and specificity of the Montreal cognitive assessment modified for individuals who are visually impaired Validation of a Telephone Version of the Mini-Mental State Examination Telephone Interview for Cognitive Status: Creating a crosswalk with the Mini-Mental State Examination A critical review of the use of telephone tests to identify cognitive impairment in epidemiology and clinical research Utility of TICS-M for the assessment of cognitive function in older adults Validation and Normative Data for the Modified Telephone Interview for Cognitive Status: The Sydney Memory and Ageing Study Neuropsychological Test Administration by Videoconference: A Systematic Review and Meta-Analysis Online assessment of risk factors for dementia and cognitive function in healthy adults The Effect of an Online Cognitive Training Package in Healthy Older Adults: An Online Randomized Controlled Trial Utility, reliability, sensitivity and validity of an online test system designed to monitor changes in cognitive function in clinical trials The dose-dependent cognitive effects of acute administration of Ginkgo biloba to healthy young volunteers Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults Integrated Cognitive Assessment: Speed and Accuracy of Visual Processing as a Reliable Proxy to Cognitive Performance A selfadministered, artificial intelligence (AI) platform for cognitive assessment in multiple sclerosis (MS) Gallery Game: Smartphone-based assessment of long-term memory in adults at risk of Alzheimer's disease A rapid, mobile neurocognitive screening test to aid in identifying cognitive impairment and dementia (braincheck): Cohort study Computerbased tools for assessing micro-longitudinal patterns of cognitive function in older adults Using linguistic features longitudinally to predict clinical scores for Alzheimer's disease and related dementias Linguistic features identify Alzheimer's disease in narrative speech Comparing traditional and digitized cognitive tests used in standard clinical evaluation -a study of the digital application minnemera The Use of a Virtual Reality Platform for the Assessment of the Memory Decline and the Hippocampal Neural Injury in Subjects with Mild Cognitive Impairment: The Validity of Smart Aging Serious Game (SASG) Five-year biomarker progression variability for Alzheimer's disease dementia prediction: Can a complex instrumental activities of daily living marker fill in the gaps? Online platforms involving cognitive tests provide a valuable means of carrying out remote cognitive assessments.
    keywords: adults; assessment; clinics; covid-19; data; dementia; disease; function; impairment; level; mci; memory; patients; scores; study; telephone; test; use
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        item: #4855 of 7819
          id: cord-316692-r04cqr8e
      author: Seo, Yoshihiro
       title: Review of the efforts of the Japanese Society of Echocardiography for coronavirus disease 2019 (COVID-19) during the initial outbreak in Japan
        date: 2020-09-05
       words: 2714
      flesch: 38
     summary: With increasing evidence of a close interaction between cardiovascular conditions and COVID-19, there was a growing demand for echocardiography in COVID-19 patients. Since echocardiography requires physical contact between the examiner and the patient, infection of the healthcare providers was the biggest concern in performing echocardiography for COVID-19 patients.
    keywords: covid-19; echocardiography; infection; jse; pandemic; society
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        item: #4856 of 7819
          id: cord-316702-dj2fo8sn
      author: Vignesh, Ramachandran
       title: Is Herd Immunity Against SARS-CoV-2 a Silver Lining?
        date: 2020-09-30
       words: 3257
      flesch: 31
     summary: (2020) Longitudinal profile of antibodies against SARS-coronavirus in SARS patients and their clinical significance Persistence of Antibodies against Middle East Respiratory Syndrome Coronavirus Severe Acute Respiratory Syndrome Coronavirus 2-Specific Antibody Responses in Coronavirus Disease Antibody responses to SARS-CoV-2 in patients with COVID-19 Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals Pre-existing immunity to SARS-CoV-2: the knowns and unknowns Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans Pre-existing and de novo humoral immunity to SARS-CoV-2 in humans Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 Systems-level immunomonitoring from acute to recovery phase of severe COVID-19 Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications Reappearance of effector T cells is associated with recovery from COVID-19 SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19 Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications. This preexisting cross-reactive T and B cell immunity to SARS-CoV-2 may have wide implications as this could explain differential clinical outcomes in COVID-19 patients, disease severity, vaccine development, and important in accessing herd immunity for SARS-CoV-2 viral infection/COVID-19 disease.
    keywords: cell; cov-2; covid-19; herd; immunity; infection; patients; sars
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        item: #4857 of 7819
          id: cord-316705-3wzurnfp
      author: Lalmuanawma, Samuel
       title: Applications of Machine Learning and Artificial Intelligence for Covid-19 (SARS-CoV-2) pandemic: A review
        date: 2020-06-25
       words: 2939
      flesch: 29
     summary: Concerning contact tracing, studies have proven the use of ML and AI in augmentation of contact tracing process against infectious Chronic Wasting disease [36] . This paper aims to comprehensively review the role of AI and ML as one significant method in the arena of screening, predicting, forecasting, contact tracing, and drug development for SARS-CoV-2 and its related epidemic.
    keywords: contact; covid-19; drug; learning; model; pandemic; tracing
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        item: #4858 of 7819
          id: cord-316712-1ngcwdln
      author: Laxminarayan, Ramanan
       title: India’s Battle against COVID-19: Progress and Challenges
        date: 2020-08-24
       words: 2593
      flesch: 51
     summary: India News, Hindustan Times Statewise estimates of current hospital beds, intensive care unit (ICU) beds and ventilators in India: are we prepared for a surge in COVID-19 hospitalizations? As of August 3, 2020, India was third in the world in the number of reported SARS-CoV-2 infections (2,456,785) and fourth in the number of reported COVID-19 deaths (48,117).
    keywords: covid-19; deaths; disease; india; infections; testing
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        item: #4859 of 7819
          id: cord-316718-7gtgqmcn
      author: Murphy, D. L.
       title: Occupational Exposures and Programmatic Response to COVID-19 Pandemic: An Emergency Medical Services Experience
        date: 2020-05-24
       words: 3698
      flesch: 48
     summary: In response, EMS was using large quantities of PPE to address this uncertainty, though the prevalence of confirmed COVID-19 EMS encounters was estimated to be less than 5%. We used logistic regression to determine if calendar time was associated with a temporal trend in adequate PPE use and EMS provider exposure.
    keywords: covid-19; ems; encounters; exposure; patients; ppe; providers; risk
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        item: #4860 of 7819
          id: cord-316728-vyfkmniu
      author: Benyounes, Nadia
       title: Echocardiography in Confirmed and Highly Suspected Symptomatic COVID-19 Patients and Its Impact on Treatment Change
        date: 2020-09-16
       words: 3456
      flesch: 43
     summary: To explore echocardiography's impact on the management of COVID-19 patients. is is why we had to perform TTEs/TEEs on COVID-19 patients admitted to our institution.
    keywords: change; covid-19; echocardiography; patients; study; treatment; troponin
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        item: #4861 of 7819
          id: cord-316743-q6gbxghx
      author: Madhu, S. V.
       title: Post COVID-19 diabetes care—lessons and challenges
        date: 2020-06-04
       words: 1692
      flesch: 37
     summary: DPP4 inhibitors are another class of antidiabetic agents which are believed to have a potential to reduce the incidence and severity of complications associated with COVID-19 infections particularly in diabetic patients. A high degree of alertness with frequent self-monitoring of blood glucose levels is certainly advisable in known diabetic patients particularly insulin users to reduce the risk of being affected with COVID-19 infection and avoid any undesirable consequence should they get infected.
    keywords: covid-19; diabetes; infections; patients
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        item: #4862 of 7819
          id: cord-316764-ps89rxuy
      author: Liu, Zheng
       title: At the center of the COVID‐19 pandemic: Lessons learned for otolaryngology‐head and neck surgery in China
        date: 2020-05-12
       words: 1777
      flesch: 37
     summary: A fever clinic has been set up to identify patients with COVID-19 and to separate them from COVID-19 negative patients with fever and/or respiratory symptoms similar to those found in COVID-19. Patients who have remained in Beijing for over 14 days are permitted to enter, and patients are scheduled for surgical procedures only when the test for COVID-19 is negative.
    keywords: beijing; covid-19; hospital; medical; patients; tracheostomy
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        item: #4863 of 7819
          id: cord-316805-6rshrecb
      author: Hossain, M. A.
       title: Knowledge, Attitudes, and Fear of COVID-19 during the Rapid Rise Period in Bangladesh
        date: 2020-06-18
       words: 4387
      flesch: 52
     summary: Conclusions: Overall, Bangladeshis reported a high prevalence of self-isolation, positive preventive health behaviors related to COVID-19, and moderate to high fear levels. Knowledge and education levels were directly associated, with Bachelor of Science (BSc) degree holders reporting higher knowledge of COVID-19 symptoms and precautions than any other education group (p=<.005).
    keywords: covid-19; fear; knowledge; license; medrxiv; preprint; study; subjects
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        item: #4864 of 7819
          id: cord-316837-xwc9d5sy
      author: Morgan, Catrin
       title: Should I use steroid injections to treat shoulder pain during the COVID-19 pandemic?
        date: 2020-09-09
       words: 647
      flesch: 37
     summary: The use of non-steroidal anti-inflammatory drugs (NSAIDs) 313 in patients with World Health Organisation. 27 The only national guidelines issued in the USA was a joint statement on March 27 th 2020, by 29 the American Society of Regional Anesthesia and Pain Medicine (ASRA) and European 30 Society of Regional Anesthesia and Pain Therapy (ESRA) that advised against elective pain 31 procedures and recommended that clinicians consider evaluating risks/benefits of steroid 32 injections and use a decreased dose, especially in high-risk patient populations 1 The first line of treatment for shoulder pain is usually non-steroidal anti-inflammatory drugs 51 (NSAIDs) and physical therapy.
    keywords: covid-19; pandemic
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        item: #4865 of 7819
          id: cord-316842-mnt12ot2
      author: Medline, MPH
       title: Evaluating the Efficacy of Stay-At-Home Orders: Does Timing Matter?
        date: 2020-06-03
       words: 2755
      flesch: 51
     summary: https://doi.org/10.1101/2020.05.30.20117853 doi: medRxiv preprint mandate, by controlling for the case rate of disease for each country and US state included in our regression models. Our primary outcome variables were the number of days from the first reported case of COVID-19 to the peak of daily cases and to the peak of daily deaths, in each respective country and US state included in our analysis.
    keywords: case; covid-19; home; medrxiv; preprint
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        item: #4866 of 7819
          id: cord-316845-k9zvsfvj
      author: Robertson, Mary M.
       title: Gilles de la Tourette Syndrome: advice in the times of COVID-19
        date: 2020-04-28
       words: 3764
      flesch: 48
     summary: Finally, it has been shown that elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict progression in COVID-19 patients (Zheng et al., 2020b). Coronavirus particles are surrounded by a fatty outer layer called an envelope and usually are spherical when visualised under an electron microscope, with a corona of club-shaped spikes on their surface (Wu et al., 2020).
    keywords: anxiety; covid-19; gts; pandemic; patients; sars; symptoms
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        item: #4867 of 7819
          id: cord-316878-zemaygnt
      author: Johnson, Stephanie B.
       title: Advancing Global Health Equity in the COVID-19 Response: Beyond Solidarity
        date: 2020-08-25
       words: 2635
      flesch: 40
     summary: In the context of global health, solidarity is often invoked normatively in connection with providing assistance to poor countries (Prainsack and Buyx 2012) . Prainsack and Buyx offer that of authors writing about solidarity and global health, most agree that solidarity should help to materialize a better distribution of resources and more equal access to healthcare across the globe.
    keywords: countries; covid-19; global; health; research; solidarity
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        item: #4868 of 7819
          id: cord-316906-0x3j41ae
      author: Woznitza, N.
       title: COVID-19: A case series to support radiographer preliminary clinical evaluation
        date: 2020-04-11
       words: 1030
      flesch: 41
     summary: Medical Radiation Practice Board of Australia Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study SARS-CoV-2 induced diarrhoea as onset symptom in patient with COVID-19 Thoracic imaging in COVID-19 infection: guidance for the reporting radiologist CT abdomen with left lower lobe ground glass opacification (Indeterminate COVID-19). A 93-year-old female presented to the emergency department with a 10-day history of shortness of breath (oxygen saturation COVID-19) .
    keywords: chest; covid-19; opacification
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        item: #4869 of 7819
          id: cord-316918-mz5r7yiy
      author: Rubin, Geoffrey A.
       title: Performance of electrophysiology procedures at an academic medical center amidst the 2020 coronavirus (COVID‐19) pandemic
        date: 2020-04-20
       words: 2807
      flesch: 33
     summary: Most crucially, the surge in COVID-19 positive patients that have already overwhelmed the New York City hospital system requires conservation of hospital resources including personal protective equipment (PPE), reassignment of personnel, and reorganization of institutions, including the EP laboratory. Unless urgent/emergent, we have avoided performing procedures on COVID-19 infected patients in the EP laboratory to prevent transmission not only during transport to the laboratory, but also to prevent seeding the lab itself in the case of a prolonged operation.
    keywords: cases; covid-19; emergent; laboratory; patients; ppe; procedures
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        item: #4870 of 7819
          id: cord-316923-b81uaooh
      author: Luks, Andrew M.
       title: Reply: COVID-19 Lung Injury and “Typical” Acute Respiratory Distress Syndrome: The Danger of Presumed Equivalency
        date: 2020-09-17
       words: 1532
      flesch: 37
     summary: On a broader level, the author seems to imply that all of the severe pathology in COVID-19 lung injury is related to ventilator-induced lung injury (VILI) rather than evolution of the disease. In patients randomized to the MT arm, the initial tube placement could have COVID-19 lung injury and high-altitude pulmonary edema: a false equation with dangerous implications Covid-19 in critically ill patients in the Seattle region: case series Respiratory pathophysiology of mechanically ventilated patients with COVID-19: a cohort study Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19 Post-mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction The pulmonary vascular lesions of the adult respiratory distress syndrome COVID-19 does not lead to a typical acute respiratory distress syndrome PROSEVA Study Group.
    keywords: covid-19; injury; lung; patients
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        item: #4871 of 7819
          id: cord-316925-l56cos15
      author: Carriedo, Dr. Alejandro
       title: COVID-19, Psychological Well-being and Physical Activity Levels in Older Adults during the Nationwide Lockdown in Spain
        date: 2020-08-22
       words: 4551
      flesch: 45
     summary: International Physical Activity Questionnaire (IPAQ): 12-country reliability and validity Evidence to support including lifestyle light-intensity recommendations in physical activity guidelines for older adults Daily sitting time and all-cause mortality: a meta-analysis Objective Light Intensity Physical Activity Associations With Rated Health in Older Adults The ASA's statement on p-values: context, process, and purpose Statistical Power Analysis for the Behavioral Sciences Resilience and physical and mental well-being in adults with and without HIV A meta-analysis of the trait resilience and mental health Impact of resilience on health in older adults: a crosssectional analysis from the International Mobility in Aging Study (IMIAS) Unfortunately, we did not include this information, and it could be considered another limitation, because it is not possible to determine if the COVID-19 has led to changes in PA levels or mental health symptoms.
    keywords: adults; affect; covid-19; health; recommendations; resilience; study; symptoms
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        item: #4872 of 7819
          id: cord-316928-ivwz7jxi
      author: Anzola, Gian Paolo
       title: Neither ACEIs nor ARBs are associated with respiratory distress or mortality in COVID-19 results of a prospective study on a hospital-based cohort
        date: 2020-09-23
       words: 3464
      flesch: 44
     summary: O2%, lymphocyte count, creatinine, proportion of AST ≥ 32, of creatinine ≥ 1.00 (lab cutoff) and CRP were statistically different both in MILD and in SEVERE RD patients (Tables 1, 2 ). For AST and chronic renal failure, the difference from NO RD was significant only in SEVERE RD patients ( Table 1 ).
    keywords: arbs; covid-19; disease; mild; patients; severe
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        item: #4873 of 7819
          id: cord-316938-64jxtg9y
      author: Blasi, Annabel
       title: In vitro hypercoagulability and ongoing in vivo activation of coagulation and fibrinolysis in COVID‐19 patients on anticoagulation
        date: 2020-08-06
       words: 3076
      flesch: 36
     summary: The high thrombosis risk in COVID-19 patients has been linked to a hypercoagulable state that has not been well-defined. Test results were compared between COVID-19 patients and healthy controls, and between patients admitted to the ICU and the ward, using the Mann-Whitney U test.
    keywords: article; coagulation; covid-19; icu; levels; patients; plasma; thrombin
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        item: #4874 of 7819
          id: cord-316943-ef3i96bo
      author: Sciberras, Justine
       title: The burden of type 2 diabetes pre-and during the COVID-19 pandemic – a review
        date: 2020-10-19
       words: 4871
      flesch: 41
     summary: Coronavirus infections and type 2 diabetes-shared pathways with therapeutic implications Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Spe ci a l R e p or t Renin -Angiotensin -Aldosterone System Inhibitors in Patients with Covid-19 The use of renin angiotensin system inhibitor on mortality in patients with coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis Continued In-Hospital Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use in Hypertensive COVID-19 Patients Is Associated With Positive Clinical Outcome COVID-19 panic, solidarity and equity-the Malta exemplary experience Enforced inactivity in the elderly and diabetes risk: initial estimates of the burden of an unintended consequence of COVID-19 lockdown, medRxiv Clinical aspects of physical exercise for diabetes/metabolic syndrome Prevalence of obesity in Malta World Health Organization How do we identify people at high risk of type 2 diabetes and help prevent the condition from developing World Health Organization noncommunicable diseases country profiles Socioeconomic status and prevalence of type 2 diabetes in mainland China, Hong Kong and Taiwan: a systematic review Prevalence of diabetes and prediabetes in 15 states of India: results from the ICMR-INDIAB population-based cross-sectional study COVID-19 pandemic, coronaviruses, and diabetes mellitus Factors leading to high morbidity and mortality of COVID-19 in patients with type 2 diabetes Endocrine and metabolic link to coronavirus infection Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS COVID-19 and diabetes: The why, the what and the how Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensinconverting enzyme 2 COVID-19, renin-angiotensin system and endothelial dysfunction Outcomes in patients with COVID-19 infection taking ACEI/ARB Preventing a covid-19 pandemic Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
    keywords: burden; covid-19; diabetes; health; healthcare; pandemic; patients; population; risk; type
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        item: #4875 of 7819
          id: cord-316944-xt09q1z5
      author: Preis, Heidi
       title: Vulnerability and Resilience to Pandemic-Related Stress Among U.S. Women Pregnant at the Start of the COVID-19 Pandemic
        date: 2020-09-06
       words: 2071
      flesch: 27
     summary: Binary logistic regression was used to calculate odds ratios for high stress. Neither gestational age, fertility treatment (endorsed by 10.6% of the sample), psychiatric medication use (endorsed by 12.1% of the sample), nor diagnosis of COVID-19 during pregnancy were significant predictors of high stress in the unadjusted or adjusted models, indicating that high stress was equally common for women irrespective of these characteristics.
    keywords: pandemic; pregnancy; stress; women
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        item: #4876 of 7819
          id: cord-316972-5jtd5ytz
      author: Zhang, Wen-rui
       title: Mental Health and Psychosocial Problems of Medical Health Workers during the COVID-19 Epidemic in China
        date: 2020-04-09
       words: 2852
      flesch: 43
     summary: We explored whether medical health workers had more psychosocial problems than nonmedical health workers during the COVID-19 outbreak. Compared with nonmedical health workers (n = 1,255), medical health workers (n = 927) had a higher prevalence of insomnia (38.4 vs. 30.5%, p < 0.01), anxiety (13.0 vs. 8.5%, p < 0.01), depression (12.2 vs. 9.5%; p< 0.04), somatization (1.6 vs. 0.4%; p < 0.01), and obsessive-compulsive symptoms (5.3 vs. 2.2%; p < 0.01).
    keywords: anxiety; covid-19; health; medical; symptoms; workers
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        item: #4877 of 7819
          id: cord-316987-3nhqx2qn
      author: London, Viktoriya
       title: Caring for Pregnant Patients with COVID-19: Practical Tips Getting from Policy to Practice
        date: 2020-05-07
       words: 1826
      flesch: 45
     summary: Two aspects of outpatient care needed to be considered: (1) how to change practice to minimize viral exposure of healthy patients and providers, and (2) how to utilize outpatient resources to off-load some of the inpatient burden of taking care of COVID-19 patients. Intravenous (IV) extension tubing should be utilized to allow the IV pumps to be placed outside the rooms, decreasing nurses' exposure to COVID-19 patients.
    keywords: care; coronavirus; covid-19; labor; patients
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        item: #4878 of 7819
          id: cord-317002-jcjenti0
      author: Francesco, Garaci
       title: Venous cerebral thrombosis in COVID-19 patient
        date: 2020-05-01
       words: 667
      flesch: 31
     summary: DIC is a severe complication in COVID-19 patients and it has been related to poor prognosis and increased mortality (71.4% of patient who die of COVID-19) (2) . Although arterial ischemic strokes may be associated in COVID-19 patients this case demonstrates that venous cerebral thrombosis should be rule out in patients with neurological symptoms
    keywords: covid-19; patients
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        item: #4879 of 7819
          id: cord-317016-codk0by1
      author: Trivizakis, Eleftherios
       title: Advancing COVID-19 differentiation with a robust preprocessing and integration of multi-institutional open-repository computer tomography datasets for deep learning analysis
        date: 2020-09-11
       words: 3274
      flesch: 35
     summary: First case of 2019 novel coronavirus in the United States Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia CT imaging features of 2019 novel coronavirus (2019-NCoV) Clinical features of patients infected with 2019 novel coronavirus in Interpretable artificial intelligence framework for COVID-19 screening on chest X-rays Covid-19: automatic detection from X-ray images utilizing transfer learning with convolutional neural networks Using artificial intelligence to detect COVID-19 and community-acquired pneumonia based on pulmonary CT: Evaluation of the diagnostic accuracy A fully automatic deep learning system for COVID-19 diagnostic and prognostic analysis Clinically applicable AI system for accurate diagnosis, quantitative measurements, and prognosis of COVID-19 pneumonia using computed tomography Application of deep learning technique to manage COVID-19 in routine clinical practice using CT images: Results of 10 convolutional neural networks Deep learning enables accurate diagnosis of novel coronavirus (COVID-19) with CT images Deep learning-based detection for COVID-19 from chest CT using weak label Rapid AI development cycle for the coronavirus (COVID-19) pandemic: Initial results for automated detection and patient monitoring using deep learning CT image analysis Lung infection quantification of COVID-19 in CT images with deep learning Automatic detection of coronavirus disease (COVID-19) in x-ray and CT images: A machine learning-based approach Weakly supervised deep learning for COVID-19 infection detection and classification from CT images Residual attention U-Net for automated multi-class segmentation of COVID-19 chest CT images SARS-CoV-2 CT-scan dataset: A large dataset of real patients CT scans for SARS-CoV-2 identification A CT scan dataset about COVID-19 COVID-19 CT lung and infection segmentation dataset U-net: Convolutional networks for biomedical image segmentation The Lung Image Database Consortium (LIDC) and Image Database Resource Initiative (IDRI): a completed reference database of lung nodules on CT scans Very deep convolutional networks for large-scale image recognition Rethinking the inception architecture for computer vision Learning transferable architectures for scalable image recognition Densely connected convolutional networks MobileNetV2: Inverted Residuals and Linear Bottlenecks. Ardakani et al (22) utilized 10 pre-trained convolutional networks as the backbone of their classifier, achieving the best AUC score of 99.4%, SN of 100%, SPC of 99% and ACC of 99.5%, for distinguishing COVID-19 pneumonia from other types of pneumonia (viral and bacterial).
    keywords: analysis; coronavirus; covid-19; dataset; learning; model; pneumonia; segmentation
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        item: #4880 of 7819
          id: cord-317058-anvmj4li
      author: Liu, Xinkui
       title: Analysis of clinical features and early warning signs in patients with severe COVID-19: A retrospective cohort study
        date: 2020-06-26
       words: 3366
      flesch: 48
     summary: A higher number of patients showed signs of dyspnea in the severe group than in the non-severe group in our study, indicating that dyspnea was one of the main symptoms among patients with severe COVID-19; thus, a daily evaluation for dyspnea should be conducted among COVID-19 patients. In this study, we summarized the clinical features of COVID-19 patients and identified the early warning signs of severe COVID-19, which will help physicians determine which patients require further observation.
    keywords: covid-19; group; lymphocyte; patients; risk; study
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        item: #4881 of 7819
          id: cord-317062-nn0u82dp
      author: Jenkins, Aaron
       title: Nested ecology and emergence in pandemics
        date: 2020-08-12
       words: 739
      flesch: 25
     summary: The condition of the environments in which we live, another source of infectious diseases, requires a similar level of understanding with associated policy directives, such as restricting expansion of large-scale extractive uses in intact landscapes, planning infrastructure development to avoid habitat fragmentation, and avoiding disruption of natural fire and flood regimes. With emerging infectious diseases, preventive programmes to minimise the risk of animal-tohuman disease transmission are gaining momentum.
    keywords: covid-19; health; systems
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        item: #4882 of 7819
          id: cord-317080-kn56oov6
      author: Quadri, Sayed. A.
       title: COVID-19 and Religious Congregations: Implications for Spread of Novel Pathogens
        date: 2020-05-07
       words: 291
      flesch: 52
     summary: COVID 19 is spread through droplet and basic reproduction rate, a 23 measure of transmissibility of the virus, ranges from 2.24 to 3.58 (Zhao et al., 2020) . The refusal to suspend such gatherings could lead to potential widespread dispersal of infections.
    keywords: spread
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        item: #4883 of 7819
          id: cord-317085-qc8bfb9g
      author: Zhang, Nan
       title: Risk Factors for Poor Outcomes of Diabetes Patients With COVID-19: A Single-Center, Retrospective Study in Early Outbreak in China
        date: 2020-09-24
       words: 4757
      flesch: 49
     summary: Furthermore, the value of hs-CRP, ESR and PCT in the severe patients were significantly higher than those value in non-severe patients (p < 0.05). A retrospective cohort study was undertaken on diabetic patients with COVID-19 infection in Central Hospital of Wuhan, a designated medical institution in SARS-CoV-2 infection.
    keywords: clinical; covid-19; diabetes; events; infection; iqr; patients; sars; study
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        item: #4884 of 7819
          id: cord-317092-5qba9jiq
      author: Singh, Tulika
       title: Lessons from COVID-19 in children: Key hypotheses to guide preventative and therapeutic strategies
        date: 2020-05-08
       words: 4974
      flesch: 38
     summary: Of the few reports of severe COVID-19 disease in children, all three critical cases had a significant underlying or concurrent medical condition, including acute lymphoblastic leukemia (ALL), hydronephrosis, and intussusception. Specifically, underlying medical issues such as prematurity, chronic lung disease, congenital heart disease, asthma, and even lung injury from vaping and smoking, may result in an increase in the risk for severe COVID-19 disease.
    keywords: adults; children; coronavirus; cov-2; covid-19; disease; infection; sars
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        item: #4885 of 7819
          id: cord-317126-j3o9cfkv
      author: Wang, Jigang
       title: Preparedness is essential for malaria-endemic regions during the COVID-19 pandemic
        date: 2020-03-17
       words: 1238
      flesch: 46
     summary: 2 Africa needs to be prepared to deal with COVID-19, given the infectious potential of the disease and its capacity to undermine malaria control efforts. The emergence of Ebola in malaria-endemic countries, including Guinea, Liberia, and Sierra Leone, led to a public health emergency and dealt a heavy blow to malaria control efforts.
    keywords: covid-19; ebola; health; malaria
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        item: #4886 of 7819
          id: cord-317151-cxx5pcln
      author: Papa, Alfredo
       title: Covid-19 and the management of patients with inflammatory bowel disease: a practical decalogue for the post-pandemic phase
        date: 2020-10-24
       words: 5035
      flesch: 37
     summary: Coronavirus situation report Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms Evidence for gastrointestinal infection of SARS-CoV-2 Challenges in the care of IBD patients during the CoVID-19 pandemic: report from a Red Zone area in Northern Italy Serious infection and mortality in patients with Crohn's disease: more than 5 years of follow-up in the TREAT registry Anti-TNFalpha agents in inflammatory bowel disease and course of COVID-19 Impact of COVID-19 pandemic on the daily management of biotechnological therapy in inflammatory bowel disease patients: reorganisational response in a high-volume Italian inflammatory bowel disease centre European Crohn's and Colitis Organization. A retrospective study from the United States including a large cohort of IBD patients reported that the incidence rate of COVID-19 per 1000 IBD patients was of 0.61 in patients treated with anti-TNF-α and 1 in those not in treatment with anti-TNF-α (p = 0.618).
    keywords: bowel; covid-19; disease; face; ibd; pandemic; patients; sars; surgery; therapy; use
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        item: #4887 of 7819
          id: cord-317167-hzcl1hw3
      author: Rodgers, Rachel F.
       title: The impact of the COVID‐19 pandemic on eating disorder risk and symptoms
        date: 2020-06-01
       words: 2761
      flesch: 26
     summary: The Lancet Psychiatry COVID-19 Barometer: Consumer attitudes, media habits and expectations Stress-induced eating in women with binge-eating disorder and obesity Social support networks and eating disorders: An integrative review of the literature Everybody knows that mass media are/are not [pick one] a cause of eating disorders: A critical review of evidence for a causal link between media, negative body image, and disordered eating in females A survey study of attitudes toward, and preferences for, e-therapy interventions for eating disorder psychopathology Eating disorders and social support: Perspectives of recovered individuals Coping strategies in eating disorders Effects of acute and chronic sleep deprivation on eating behaviour Persistence of poor sleep predicts the severity of the clinical condition after 6 months of standard treatment in patients with eating disorders. In addition, elevated rates of stress and negative affect due to the pandemic and social isolation may also contribute to increasing risk.
    keywords: covid-19; eating; media; pandemic; risk
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        item: #4888 of 7819
          id: cord-317196-3bub3fy0
      author: Sammons, Morgan T.
       title: Psychological Practice and the COVID-19 Crisis: A Rapid Response Survey
        date: 2020-05-08
       words: 3512
      flesch: 40
     summary: Telepsychology practice went from 29% of users employing online platforms for a portion of their practice to over 80% conducting almost all their practice online. Additionally, most psychologists had some level of exposure to telepsychology practice even if they were not doing it regularly.
    keywords: covid-19; crisis; health; practice; psychologists; respondents; services; telepsychology; years
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        item: #4889 of 7819
          id: cord-317238-uszhwugw
      author: Parodi, Aurora
       title: Coronavirus disease 2019 (COVID 19) and Malaria. Have anti glycoprotein antibodies a role?
        date: 2020-06-25
       words: 869
      flesch: 48
     summary: So we think that are not underestimation of the number of asymptomatic people of black people affected by COVID-19. In the northern Italian regions the presence of African people, usually employed in iron-steel factories and agricultural works, is high.
    keywords: covid-19; malaria; people
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        item: #4890 of 7819
          id: cord-317242-e7000i2u
      author: Gandhi, Darshan
       title: Review of X-ray and computed tomography scan findings with a promising role of point of care ultrasound in COVID-19 pandemic
        date: 2020-09-28
       words: 2932
      flesch: 47
     summary: Volume rendered chest CT imaging has been successfully utilized in COVID-19 patients to delineate disease, demonstrate September 28, 2020 Volume 12 Issue 9 newly developed lesions and ascertain their distribution The full spectrum of chest CT findings observed in COVID-19 disease includes ground-glass opacification (pure, with crazy-paving, or with accompanying consolidation), pure consolidation, air bronchograms, pleural effusions, lymphadenopathy (Figures 3, 4 and 5)
    keywords: chest; covid-19; disease; findings; patients
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        item: #4891 of 7819
          id: cord-317265-n6x0r58i
      author: Singh, Varsha
       title: Can Vitamins, as Epigenetic Modifiers, Enhance Immunity in COVID-19 Patients with Non-communicable Disease?
        date: 2020-07-13
       words: 3942
      flesch: 26
     summary: The purpose of this review is to provide evidence to consider vitamins as epigenetic modifiers to enhance immunity and reduce inflammatory response in COVID-19 patients with non-communicable diseases. It is noteworthy that this individualized approach has a potential of obtaining positive results for COVID-19 patients, if individuals are thoroughly tested and treated according to their unique metabolic function.
    keywords: cancer; covid-19; disease; factors; ncds; non; patients; response; risk; system; vitamin
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        item: #4892 of 7819
          id: cord-317283-0zzs5cy8
      author: Nicoletti, Angela
       title: Screening of COVID-19 in children admitted to the hospital for acute problems: preliminary data
        date: 2020-05-11
       words: 1834
      flesch: 41
     summary: Laboratory indices and chest X-ray descriptions, in our patients and in children and adolescents with COVID-19 infections reported in the literature, are also presented. The majority of COVID-19 positive children had a close contact with an infected case or were family cluster cases and their age, at onset of disease, ranged from 1.5 months to 17 years (4) .
    keywords: children; coronavirus; covid-19; infection; patients; symptoms
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        item: #4893 of 7819
          id: cord-317323-wp3vh4c1
      author: Kandhari, Rajat
       title: The changing paradigm of an aesthetic practice during the COVID‐19 pandemic: An expert consensus
        date: 2020-10-28
       words: 3110
      flesch: 48
     summary: Can Effect of surgical masks worn concurrently over N95 filtering facepiece respirators: extended service life versus increased user burden Surgical mask placement over N95 filtering facepiece respirators: physiological effects on healthcare workers Decontaminating N95 masks with ultraviolet germicidal irradiation (UVGI) does not impair mask efficacy and safety: a systematic review Extended use or reuse of N95 respirators during COVID-19 pandemic: An overview of national regulatory authority recommendations Respiratory performance offered by N95 respirators and surgical masks: human subject evaluation with NaCl aerosol representing bacterial and viral particle size range Hand hygiene recommendations. • Use of paper bags: While only considered single use masks, all panel members agreed to reuse of their masks.
    keywords: covid-19; mask; n95; practice; procedures; recommendations; risk; transmission; use
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        item: #4894 of 7819
          id: cord-317349-c8nrd4h9
      author: OLAPEGBA, Peter O
       title: A Preliminary Assessment of Novel Coronavirus (COVID-19) Knowledge and Perceptions in Nigeria
        date: 2020-04-15
       words: 2025
      flesch: 46
     summary: There is 10 need for further research to build the evidence base for the study of COVID-19 knowledge and 11 precautionary measures. Their perceptions of COVID-19 bear implications across public health initiatives, compliance with precautionary behavior as well as bilateral relations with foreign nations.
    keywords: covid-19; knowledge; license; preprint; respondents
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        item: #4895 of 7819
          id: cord-317357-l2y2onmn
      author: Talarico, Valentina
       title: Preliminary epidemiological analysis on children and adolescents with novel coronavirus disease (2019-nCoV) in a central area of Calabria Region
        date: 2020-05-11
       words: 744
      flesch: 43
     summary: In suspected cases, a nasal and pharyngeal swab specimens positive for 2019-nCoV nucleic acid using real-time reverse-transcriptase polymerase-chain-reaction (RT-PCR) assay is requested to confirm COV-ID-19 infection. Sir, In December 2019, a novel coronavirus (2019-nCoV) was detected in three patients with pneumonia connected to the cluster of acute respiratory illness cases from Wuhan, China (1) .
    keywords: cases; children; covid-19
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        item: #4896 of 7819
          id: cord-317371-v7hmc9sj
      author: Zhang, Xiaolei
       title: Predicting turning point, duration and attack rate of COVID-19 outbreaks in major Western countries
        date: 2020-04-20
       words: 1896
      flesch: 51
     summary: To identify the turning point and predict the further spread of COVID-19 outbreaks while accounting for governments enforcement of stay-at-home advises/orders, social distancing, lockdowns, and quarantines against COVID-19, we combine the power law with the exponential law for daily new cases based on a segmented Poisson model. Unlike the widely used log-transformed linear model, our Poisson modeling approach enables us to deal with daily new cases as a count response with many zeros.
    keywords: cases; countries; covid-19; outbreak
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        item: #4897 of 7819
          id: cord-317399-693q80xo
      author: Al Wahaibi, Adil
       title: COVID-19 epidemic monitoring after non-pharmaceutical interventions: the use of time-varying reproduction number in a country with a large migrant population
        date: 2020-08-20
       words: 3650
      flesch: 50
     summary: With the increasing numbers of COVID-19 cases in Oman, our study showed the feasibility of using the time-varying Rt to assess and explain transmissibility dynamics and epidemic progression. Allowing 50% of governmental employees to return to work (May 31st) Opening of Muscat Governorate (May 29th) Effects of non-pharmaceutical interventions on COVID-19 cases, deaths, and demand for hospital services in the UK: a modelling study Effect of non-pharmaceutical interventions for containing the COVID-19 outbreak in China.
    keywords: cases; covid-19; data; number; population; study
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        item: #4898 of 7819
          id: cord-317413-w2xfdwea
      author: Maurya, Vimal K.
       title: Antiviral activity of traditional medicinal plants from Ayurveda against SARS-CoV-2 infection
        date: 2020-10-19
       words: 5667
      flesch: 18
     summary: Therefore, the inhibitory activity of selected active constituents against these iso-enzymes were also measured and it is found that most of active constituents do not interfere with the activity of CYP1A2, CYP2D6, CYP2C9, CYP2C19, and CYP3A4 (Table 4 ). These pathways are known to perform crucial functions like neurotransmission, regulation of sense of vision, regulation of blood pressure, smell, taste, and pain, regulation of transport of bio-chemicals, glucose metabolism, cell proliferation, Inactive Inactive Inactive Inactive Inactive Inactive Toxicity end points Carcinogenicity Inactive Inactive Active Inactive Inactive Inactive Immunotoxicity Active Inactive Active Active Active Active Mutagenicity Inactive Inactive Inactive Inactive Inactive Inactive Cytotoxicity Inactive Inactive Inactive Inactive Inactive Inactive Tox21 Nuclear receptor signalling pathways AhR Inactive Inactive Inactive Inactive Inactive Inactive AR Inactive Inactive Active Inactive Inactive Inactive AR-LBD Inactive Inactive Active Inactive Inactive Inactive Aromatase Inactive Inactive Inactive Inactive Inactive Inactive ER Inactive Inactive Inactive Inactive Inactive Inactive ER-LBD Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Inactive Cytotoxicity Inactive Inactive Inactive Inactive Inactive Inactive Tox21 Nuclear receptor signalling pathways AhR Inactive Inactive Inactive Active Inactive Inactive AR Inactive Inactive Inactive Inactive Inactive Inactive AR-LBD Inactive Inactive Inactive Inactive Inactive Inactive Aromatase Inactive Inactive Inactive Inactive Inactive Inactive ER Inactive Inactive Inactive Active Inactive Inactive ER-LBD Inactive Inactive Inactive Inactive Inactive Inactive PPAR-Gamma Inactive Inactive Inactive Inactive Inactive Inactive Tox21 Stress response pathways nrf2/ARE Inactive Inactive Active Inactive Inactive Inactive HSE Inactive Inactive Active Inactive Inactive Inactive MMP Inactive Inactive Inactive Inactive Inactive Inactive Phosphoprotein (Tumor Supressor) p53 Inactive Inactive Inactive Inactive Inactive Inactive ATAD5 Inactive Inactive Inactive Active Inactive Inactive LD Inactive Inactive Inactive Inactive Inactive Inactive Toxicity end points Carcinogenicity Inactive Inactive Inactive Inactive Inactive Inactive Immunotoxicity Inactive Inactive Inactive Inactive Inactive Inactive Mutagenicity Inactive Active Inactive Inactive Inactive Inactive Cytotoxicity Inactive Inactive Inactive Inactive Inactive Inactive Tox21 Nuclear receptor signalling pathways AhR Inactive Inactive Inactive Inactive Inactive Inactive AR Inactive Inactive Inactive Inactive Inactive Inactive AR-LBD Inactive Inactive Inactive Inactive Inactive Inactive Aromatase Inactive Inactive Inactive Inactive Inactive Inactive ER Inactive Inactive Inactive Inactive Inactive Active ER-LBD Inactive Inactive Inactive Inactive Inactive Inactive PPAR-Gamma Inactive Inactive Inactive Inactive Inactive Inactive Tox21 Stress response pathways nrf2/ARE Inactive Inactive Inactive Inactive Inactive Inactive HSE Inactive Inactive Inactive Inactive Inactive Inactive MMP Inactive Inactive Active Inactive Inactive Inactive Phosphoprotein (TumorSupressor) p53 Inactive Inactive Inactive Inactive Inactive Inactive ATAD5 Inactive Inactive Inactive Inactive Inactive Inactive LD transcription, apoptosis, and cell migration adhesion, adaptation, cell survival, and receptor for pharmaceutical agents.
    keywords: ace2; constituents; cov-2; covid-19; drug; glycoprotein; moldock; pathways; protein; receptor; sars; score; spike
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        item: #4899 of 7819
          id: cord-317429-pp6hb4q5
      author: Aslam, Saima
       title: COVID-19: Yet another coronavirus challenge in transplantation
        date: 2020-03-14
       words: 1407
      flesch: 39
     summary: Rolling updates on coronavirus disease (COVID-19) COVID-19) in the Early transmission dynamics in Wuhan, China, of novel coronavirus−infected pneumonia Clinical characteristics of coronavirus disease 2019 in China Characteristics of and important lessons from the coronavirus Disease 2019 (COVID-19) outbreak in China: summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China First cases of COVID-19 in heart transplantation from Angiotensin-converting enzyme 2 (ACE2) is a key modulator of the renin angiotensin system in health and disease Clinical characteristics of 24 asymptomatic infections with COVID-19 screened among close contacts in Nanjing, China A well infant with coronavirus Disease 2019 (COVID-19) with high viral load Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient Discovering drugs to treat coronavirus disease 2019 (COVID-19) Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis It is important to note that the clinical presentations were not distinct from those described in non-immunosuppressed individuals, and the patient with severe disease presented with a viral prodrome, displayed the typical findings on CT scan imaging, and progressed to clinical hypoxia.
    keywords: china; coronavirus; covid-19; disease; sars
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        item: #4900 of 7819
          id: cord-317441-tnde2jp5
      author: Jewell, Jennifer S
       title: Mental Health During the COVID-19 Pandemic in the United States: Online Survey
        date: 2020-10-23
       words: 4627
      flesch: 45
     summary: [24] found that older adults were at greater risk for mental health concerns [35] . Practitioners, including health care workers and mental health specialists, can be a resource for those struggling with mental health concerns during the pandemic.
    keywords: anxiety; concern; covid-19; data; depression; health; individuals; pandemic; sample; stress
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        item: #4901 of 7819
          id: cord-317450-tp2ckb6r
      author: Robillard, R.
       title: Social, Financial and Psychological Stress during an Emerging Pandemic: Observations from a Population Web-Based Survey in the acute phase of the COVID-19 pandemic
        date: 2020-06-30
       words: 4905
      flesch: 44
     summary: Factors hypothesized a priori to be associated with stress changes were: pre-outbreak stress level, time elapsed since the pandemic declaration by the WHO, age, sex, education level, total family income, employment status, working with the general public, political views, having underage children, having travelled abroad in the past 60 days, index reflective of the number and severity of potential COVID-19 symptoms, the Dimensional Obsessive-Compulsive Scale (DOCS) contamination subscale, Big5 personality subscales, Brief Resilient Coping Scale (BRCS), having a mental disorder, alcohol and drugs use, having a physical condition at risk for COVID-19, sleep duration, quality of family relationships, and amount of time spent outdoors, interacting with other people, following the news on COVID-19, and engaging in physical and artistic activities. Perceived threats and concerns, occupational, financial and social impacts, as well as psychological stress changes relative to retrospective pre-outbreak estimates are reported.
    keywords: covid-19; license; medrxiv; outbreak; pandemic; preprint; respondents; stress; survey; version
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        item: #4902 of 7819
          id: cord-317477-h3c5kddj
      author: De Coninck, David
       title: Perceived vulnerability to disease and attitudes towards public health measures: COVID-19 in Flanders, Belgium
        date: 2020-11-01
       words: 4244
      flesch: 40
     summary: As for personality characteristics, people with high agreeableness are more convinced that public measures are necessary to protect the population's health (β = 0.10, p < 0.01), while those with high emotional stability are more supportive of public health measures (β = 0.06, p < 0.10). key: cord-317477-h3c5kddj authors: De Coninck, David; d'Haenens, Leen; Matthijs, Koen title: Perceived vulnerability to disease and attitudes towards public health measures: COVID-19 in Flanders, Belgium date: 2020-11-01 journal: Pers Individ Dif DOI: 10.1016/j.paid.2020.110220 sha: doc_id: 317477 cord_uid: h3c5kddj During the COVID-19 pandemic, governments installed measures to contain the disease.
    keywords: covid-19; crisis; health; measures; media; public
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        item: #4903 of 7819
          id: cord-317500-ufo2qgj4
      author: Scialpi, Michele
       title: Pulmonary thromboembolism in criticall ill COVID-19 patients
        date: 2020-04-24
       words: 431
      flesch: 11
     summary: Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT 2019-novel Coronavirus severe adult respiratory distress syndrome in two cases in Italy: An uncommon radiological presentation Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review Acute pulmonary embolism and COVID-19 pneumonia: a random association? COVID-19 Complicated by Acute Pulmonary Embolism Radiology: TH Open Management strategy of novel coronavirus (COVID-19) pneumonia in the radiology department: a Chinese experience The Authors declare no conflicts of interest associated for the manuscript entiltled Pulmonary thromboembolism in criticall ill COVID-19 patients
    keywords: coronavirus; covid-19
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        item: #4904 of 7819
          id: cord-317512-kx0u9955
      author: Karaye, Ibraheem M.
       title: The Impact of Social Vulnerability on COVID-19 in the U.S.: An Analysis of Spatially Varying Relationships
        date: 2020-06-26
       words: 3669
      flesch: 39
     summary: Methods Using Social Vulnerability Index and COVID-19 case count data, an ordinary least squares regression model was fitted to assess the “global” relationship between COVID-19 case counts and social vulnerability. In this study, minority status and language, household composition and transportation, and housing and disability predicted COVID-19 case counts in the U.S. Addressing the social factors that create poor health is essential to reducing inequities in the health impacts of disasters.
    keywords: case; counts; covid-19; data; health; minority; social; status; u.s; vulnerability
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        item: #4905 of 7819
          id: cord-317519-yhzv2yjs
      author: Barzilai, Nir
       title: Geroscience in the Age of COVID-19
        date: 2020-07-23
       words: 2595
      flesch: 31
     summary: Healthy aging: the ultimate preventative medicine Immunosenescence: emerging challenges for an ageing population Benefits of metformin in attenuating the hallmarks of aging Metformin as a tool to target aging Metformin: historical overview Metformin improves in vivo and in vitro B cell function in individuals with obesity and Type-2 Diabetes Metformin treatment was associated with decreased mortality in COVID-19 patients with diabetes in a retrospective analysis Observational study of metformin and risk of mortality in patients hospitalized with Covid-19 mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells mTOR inhibition improves immune function in the elderly TORC1 inhibition enhances immune function and reduces infections in the elderly A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort: immunological, physical performance, and cognitive effects Rapamycin for longevity: opinion article Innate and adaptive immunity in aging and longevity: the foundation of resilience Quantification of biological aging in young adults Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Renin-Angiotensin-Aldosterone system inhibitors in patients with Covid-19 Strategies and challenges in clinical trials targeting human aging Recognizing degenerative aging as a treatable medical condition: methodology and policy Measuring biological aging in humans: a quest The critical need to promote research of aging and aging-related diseases to improve health and longevity of the elderly population Aging health and R&D for healthy longevity must be included into the WHO Work Program Strategies must be developed for periodic frailty assessment with continuous longitudinal follow-up of older persons which may reveal not only global determinants that are conserved, but also local singularities involved in differential aging health around the world.
    keywords: age; aging; covid-19; geroscience; health; metformin
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        item: #4906 of 7819
          id: cord-317526-d3z4r0dz
      author: Bloom, Patricia P.
       title: Hepatology Consultants Often Disagree on Etiology of Abnormal Liver Biochemistries in COVID-19 but Agree on Management
        date: 2020-07-29
       words: 1280
      flesch: 39
     summary: Seven patients were discharged, six had improved liver biochemistries, and none died at the end of the study period on April 22, 2020. For the 7 discharged patients, hepatologist reviewers recommended hepatology follow-up in 3 (43%) and liver biochemistries in 6 (86%).
    keywords: biochemistries; covid-19; liver; patients
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        item: #4907 of 7819
          id: cord-317535-zep5axfo
      author: Azpiazu Landa, N.
       title: Ischemic-hemorrhagic stroke in patients with Covid-19
        date: 2020-11-07
       words: 1967
      flesch: 36
     summary: COVID-19 and the Heart Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Anestesiología y los anestesiólogos en la COVID-19 Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid -19 First case of 2019 novel coronavirus disease with Encephalitis Coexistence of Covid -19 and Acute Ischemic Stroke Report of Four Cases key: cord-317535-zep5axfo authors: Azpiazu Landa, N.; Velasco Oficialdegui, C.; Intxaurraga Fernández, K.; Gonzalez Larrabe, I.; Riaño Onaindia, S.; Telletxea Benguria, S. title: Ischemic-hemorrhagic stroke in patients with Covid-19 date: 2020-11-07 journal: nan DOI: 10.1016/j.redare.2020.08.001 sha: doc_id: 317535 cord_uid: zep5axfo Coronavirus associated severe acute respiratory syndrome (SARS-CoV-2) causes a worldwide syndrome called Covid-19 that has caused 5,940,441 infections and 362,813 deaths until May 2020.
    keywords: covid-19; days; disease; infection; patients; sars
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        item: #4908 of 7819
          id: cord-317538-i6amqpmt
      author: Krawczyk, Noa
       title: Lessons from COVID 19: Are we finally ready to make opioid treatment accessible?
        date: 2020-07-06
       words: 955
      flesch: 35
     summary: key: cord-317538-i6amqpmt authors: Krawczyk, Noa; Fingerhood, Michael I.; Agus, Deborah title: Lessons from COVID 19: Are we finally ready to make opioid treatment accessible? date: 2020-07-06 journal: J Subst Abuse Treat DOI: 10.1016/j.jsat.2020.108074 sha: doc_id: 317538 cord_uid: i6amqpmt nan J o u r n a l P r e Existing models for services both in the U.S. and other countries exemplify the potential for offering opioid treatment through more accessible mechanisms (Krawczyk, Buresh, Gordon, Blue, et al, 2019;
    keywords: covid-19; health; opioid; treatment
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        item: #4909 of 7819
          id: cord-317560-jhthcw20
      author: Duong, Lisa
       title: Letter to the Editor: Neurohospitalist and COVID-19
        date: 2020-08-10
       words: 420
      flesch: 45
     summary: Similar to observation around the world, the total number of neurological consultations has dropped during the past three months while there is increasing recognition of neurological manifestation of COVID-19. The number of neurological consultations as well as stroke alert activations has decreased by 50% during the past three months, April, May and June of this year, 2020 compared with the same time period in 2019.
    keywords: covid-19
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        item: #4910 of 7819
          id: cord-317561-ewo6vvlr
      author: Jha, Sujeet
       title: HCQ prophylaxis in COVID-19 did not show any QTc prolongation in Healthcare workers
        date: 2020-11-10
       words: 1536
      flesch: 58
     summary: key: cord-317561-ewo6vvlr authors: Jha, Sujeet; Batra, Nitish; Siddiqui, Samreen; Yadav, Ashutosh; Misra, Archa; Loomba, Menka; Sethi, Sumeet; Waghdhare, Swati title: HCQ prophylaxis in COVID-19 did not show any QTc prolongation in Healthcare workers date: 2020-11-10 journal: Indian Heart J DOI: 10.1016/j.ihj.2020.11.005 sha: doc_id: 317561 cord_uid: ewo6vvlr BACKGROUND: HCQ is a commonly recommended drug for the prophylaxis of COVID-19. We did not have any participants having any structural/congenital heart disease and none of them The present study was aimed to find any effect of HCQ prophylaxis on QTc prolongation amongst the HCWs.
    keywords: hcq; prophylaxis; qtc; study
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        item: #4911 of 7819
          id: cord-317567-19ssakh7
      author: Duroi, Iris
       title: Fatal Ischaemic Stroke During COVID-19 and Acute Lung Injury
        date: 2020-05-26
       words: 986
      flesch: 44
     summary: Prolonged deep sedation during mechanical ventilation of COVID-19 patients may delay the diagnosis of stroke. On day 7, the dose of enoxaparin was increased to 40 mg twice a day (0.5 mg/kg twice a day) based on new insights into hypercoagulability in COVID-19 patients.
    keywords: covid-19; stroke
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        item: #4912 of 7819
          id: cord-317589-03isjlif
      author: Mahdian, Soodeh
       title: Drug repurposing using computational methods to identify therapeutic options for COVID-19
        date: 2020-05-30
       words: 2394
      flesch: 48
     summary: Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods Peptide-based membrane fusion inhibitors targeting HCoV-229E spike protein HR1 and HR2 domains Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Two things about COVID-19 might need attention Asians and other races express similar levels of and share the same genetic polymorphisms of the SARS-CoV-2 cell-entry receptor Identification of critical active-site residues in angiotensinconverting enzyme-2 (ACE2) by site-directed mutagenesis Pharmacoinformatics and molecular dynamic simulation studies reveal potential inhibitors of SARS-CoV-2 main protease 3CLpro SWISS-MODEL: For this purpose, five proteins of COVID-19 (3-chymotrypsin-like protease (3CLpro), Papain-Like protease (PLpro), cleavage site, HR1 and RBD in Spike protein) were selected as target proteins for drug repositioning.
    keywords: ace2; binding; covid-19; drugs; protein; site
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        item: #4913 of 7819
          id: cord-317602-ftcs7fvq
      author: O’Reilly-Shah, Vikas N.
       title: The COVID-19 Pandemic Highlights Shortcomings in US Health Care Informatics Infrastructure: A Call to Action
        date: 2020-05-12
       words: 3072
      flesch: 34
     summary: Specifically in the United States, although efforts have been made to secure the interoperability of health care data, countervailing forces have undermined these efforts for myriad reasons. Integration of health care data with nonhealthcare source data is currently an impossibility in the United States due to lack of a universal health care identifier.
    keywords: care; covid-19; data; health; information; pandemic; public; sharing; systems
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        item: #4914 of 7819
          id: cord-317604-j8b64a1a
      author: Sahay, Sandeep
       title: Management of hospitalized patients with pulmonary arterial hypertension and COVID-19 infection
        date: 2020-06-15
       words: 2064
      flesch: 27
     summary: New onset fever, cough or myalgias might suggest COVID-19 infection; however, PAH patients receiving intravenous continuous prostacyclin infusions can present with high grade fever due to catheter infection. There are some anecdotal data suggesting that ERA can block angiotensin II receptors, which are needed for viral entry into the cells, thus offering some potential protection in PAH patients.
    keywords: covid-19; fees; hypertension; infection; pah; patients; risk
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        item: #4915 of 7819
          id: cord-317605-s9vv7rw4
      author: Zhou, Y.
       title: A New Predictor of Disease Severity in Patients with COVID-19 in Wuhan, China
        date: 2020-03-27
       words: 2939
      flesch: 53
     summary: The outcomes of patients with severe pneumonia and those with non-severe pneumonia were compared using the Statistical Package for the Social Sciences (IBM Corp., Armonk, NY, USA) to explore clinical characteristics and risk factors. Results: A total of 377 patients diagnosed with COVID-19 were enrolled in this study, including 117 with severe pneumonia and 260 with non-severe pneumonia.
    keywords: covid-19; license; medrxiv; patients; pneumonia; preprint
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        item: #4916 of 7819
          id: cord-317622-o10ntfi8
      author: Evans, Ronald M.
       title: Shining Light on the COVID-19 Pandemic: A Vitamin D Receptor Checkpoint in Defense of Unregulated Wound Healing
        date: 2020-09-11
       words: 4659
      flesch: 23
     summary: Ang II also drives adhesion molecule and extracellular matrix secretion, and ultimately ARD, fulminant fibroinflammatory multi-organ involvement (Gubernatorova et al., 2020; Liu et al., 2020b; Rockx et al., 2009) , and unchecked wound healing (Rockx et al., 2009) . Q4 The hallmark lethal complication of SARS-CoV pneumonitis is a remarkably rapid and severe respiratory syndrome that ignites an aggressive wounding response (Gralinski et al., 2013; Rockx et al., 2009 ) that strikes and incapacitates the lung.
    keywords: cells; covid-19; deficiency; et al; levels; lung; patients; response; sars; vdr; vitamin
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        item: #4917 of 7819
          id: cord-317624-qdzhncs0
      author: Choi, Min Joo
       title: Comparison of antiviral effect for mild-to-moderate COVID-19 cases between lopinavir/ritonavir versus hydroxychloroquine: A nationwide propensity score-matched cohort study
        date: 2020-10-27
       words: 4289
      flesch: 39
     summary: Nationwide retrospective case-control study was conducted to compare the effect of HCQ and LPV/r on viral shedding duration among patients with mild-to-moderate COVID-19 using the reimbursement data of National Health Insurance Service. Among these, only mild-to-moderate grade 1 patients were included in the analysis, and the effect of LPV/r or HCQ use on viral shedding duration was evaluated ( Figure 1 ).
    keywords: covid-19; group; hcq; lpv; patients; shedding
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        item: #4918 of 7819
          id: cord-317628-1inxq7t5
      author: Cuccarese, Michael F.
       title: Functional immune mapping with deep-learning enabled phenomics applied to immunomodulatory and COVID-19 drug discovery
        date: 2020-08-14
       words: 9597
      flesch: 35
     summary: However, the immune system is vastly complex and dependent on cell type and context; reliably intervening in such a highly interdependent process is a formidable drug discovery challenge. Taken together these findings suggest that SARS-CoV-2 entry protease inhibitor activity varies across cell type and species; however, remdesivir and GS-441524 show strong rescue of the viral phenoprint in all cell types tested.
    keywords: cells; compounds; covid-19; cytokine; data; disease; dose; fig; image; immune; infection; inhibitors; perturbation; phenoprint; response; sars; screening; stimuli; storm; tgf; tnf; type
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        item: #4919 of 7819
          id: cord-317648-lyxz10mo
      author: Zhou, Qi
       title: Mental health and psychosocial function of general population during the COVID‐19 epidemic in China
        date: 2020-06-11
       words: 1189
      flesch: 43
     summary: Therefore, this may have caused greater psychological stress. key: cord-317648-lyxz10mo authors: Zhou, Qi; Hu, Zhenyu; Bian, Guolin; Yu, Haihang; Li, Xingxing; Lu, Yin; Yu, Chang; Li, Xianglan; Yao, Qin; Zhou, Wenhua; Yuan, Ti‐Fei; Zhou, Dongsheng title: Mental health and psychosocial function of general population during the COVID‐19 epidemic in China date: 2020-06-11 journal: Clin Transl Med DOI: 10.1002/ctm2.103 sha: doc_id: 317648 cord_uid: lyxz10mo nan Since December 2019, COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged and rapidly spread to many countries.
    keywords: epidemic; health; population; stress
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        item: #4920 of 7819
          id: cord-317689-gp4x54pe
      author: Galanopoulou, Aristea S.
       title: EEG findings in acutely ill patients investigated for SARS‐CoV‐2/COVID‐19: A small case series preliminary report
        date: 2020-05-17
       words: 4721
      flesch: 41
     summary: A significant difference was seen in prevalence of positive blood cultures among COVID-19 negative patients (4/6, 66.7% vs COVID-19 positive (0/21, 0%) (P = .0009). We attempted a comparison with COVID-19 negative patients who would have been more likely to have similar clinical presentation and EEG indications as the COVID-19-positive patients.
    keywords: covid-19; eeg; eegs; events; negative; patients; positive; seizures; study
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        item: #4921 of 7819
          id: cord-317707-r0q7ipa6
      author: Saracco, Margherita
       title: Carrying on with Liver Transplantation during the COVID-19 emergency: Report from Piedmont Region
        date: 2020-08-07
       words: 2848
      flesch: 51
     summary: Our transplant hepatologists were spared from the full-time management of COVID-units, in order to take care of outpatient and inpatient transplant patients. The facts during the third epidemic COVID-19 in long-term liver transplant patients: preliminary experience from an Italian transplant centre in Lombardy Advance online publication Disease in a Liver Transplant Recipient Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR The COVID-19 outbreak in Italy: Initial implications for organ transplantation programs COVID-19 and liver disease Health Status of Liver Transplanted Patients During the Coronavirus Outbreak in Italy: a Large Single Center Experience From Milan Prevention of SARS-CoV-2 infection in patients with decompensated cirrhosis Marginal grafts: finding the correct treatment for fatty livers Validation of a current definition of early allograft dysfunction in liver transplant recipients and analysis of risk factors The impact of the COVID-19 outbreak on Liver Transplantation programmes in Northern Italy Preliminary Analysis of the Impact of COVID-19 Outbreak on Italian Liver Transplant Programs.
    keywords: center; covid-19; liver; patients; sars; transplant
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        item: #4922 of 7819
          id: cord-317728-0hcsblrf
      author: Aksan, Feyzullah
       title: A COVID-19 patient with intense burning pain
        date: 2020-08-10
       words: 1254
      flesch: 51
     summary: Neuropathic pain was seen in over 2% of COVID-19 patients in one observational study. While it is rare, a significant number of COVID-19 patients are afflicted by neuropathic pain, and our case illustrates that gabapentin may be effective.
    keywords: case; covid-19; pain; patient
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        item: #4923 of 7819
          id: cord-317729-ruvx9zwd
      author: Wilson, Darius Cameron
       title: Adrenomedullin in COVID-19 induced endotheliitis
        date: 2020-07-09
       words: 632
      flesch: 21
     summary: key: cord-317729-ruvx9zwd authors: Wilson, Darius Cameron; Schefold, Joerg C.; Baldirà, Jaume; Spinetti, Thibaud; Saeed, Kordo; Elke, Gunnar title: Adrenomedullin in COVID-19 induced endotheliitis date: 2020-07-09 journal: Crit Care DOI: 10.1186/s13054-020-03151-7 sha: doc_id: 317729 cord_uid: ruvx9zwd nan Darius Cameron Wilson 1* , Joerg C. Schefold 2 , Jaume Baldirà 3 , Thibaud Spinetti 2 , Kordo Saeed 4 and Gunnar Elke 5 Despite the exponential growth in research following the rapid spread of SARS-CoV-2 and subsequent COVID-19 pandemic, the underlying pathophysiological mechanisms in COVID-19 patients remain poorly understood. The assessment of MR-proADM in future COVID-19 studies may therefore provide important information into the pathophysiological mechanisms underlying endotheliitis and subsequent organ dysfunction.
    keywords: covid-19; patients
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        item: #4924 of 7819
          id: cord-317761-tkqmu1va
      author: Shukla, Ashutosh M
       title: Chloroquine and hydroxychloroquine in the context of COVID-19
        date: 2020-04-28
       words: 4115
      flesch: 33
     summary: Chloroquine is a potent inhibitor of sars coronavirus infection and spread A novel coronavirus from patients with pneumonia in China New insights into the antiviral effects of chloroquine Insights from nanomedicine into chloroquine efficacy against COVID-19 Chloroquine and nanoparticle drug delivery: a promising combination A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery Clinical cancer nanomedicine Chloroquine and hydroxychloroquine in the treatment of COVID-19 with or without diabetes: a systematic search and a narrative review with a special reference to india and other developing countries Glycopeptide antibiotics potently inhibit cathepsin l in the late endosome/lysosome and block the entry of ebola virus, middle east respiratory syndrome coronavirus (mers-cov), and severe acute respiratory syndrome coronavirus (SARS-CoV) Thus, neutralization of the acidic pH of the endosome by chloroquine or HCQ may prevent the fusion of SARS-CoV-2 with the host cell inhibiting the primary entry.
    keywords: chloroquine; covid-19; effects; hcq; hydroxychloroquine; patients; review; sars; treatment; virus
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        item: #4925 of 7819
          id: cord-317776-gw3jmalz
      author: Boreskie, Kevin F.
       title: Age is just a number – and so is frailty: Strategies to inform resource allocation during the COVID-19 pandemic
        date: 2020-04-01
       words: 937
      flesch: 49
     summary: Research should prioritize studying outcomes of older patients and frail patients with COVID-19 to better characterize these populations and inform decision-making. It is a rapid and ED-friendly method already used in every National Health Service (NHS) ED in the United Kingdom, and seems practical to use in the context of COVID-19 patients presenting to an overwhelmed hospital (Figure 1 ).
    keywords: care; covid-19; frailty
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        item: #4926 of 7819
          id: cord-317794-kd9a0ron
      author: Ahmed, Hiwa Omer
       title: The impact of social distancing and self-isolation in the last corona COVID-19 outbreak on the body weight in Sulaimani governorate- Kurdistan/Iraq, a prospective case series study
        date: 2020-09-18
       words: 4644
      flesch: 59
     summary: Is social isolation during the corona COVID -19 quarantine consistent and equally associated with emotional eating and weight gain? (13) Gaining weight is, in fact, growing risk to the health of people in developed nations and has been described as an epidemic that has become a global health concern.
    keywords: eating; gain; isolation; outbreak; patients; people; quarantine; social; weight
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        item: #4927 of 7819
          id: cord-317795-689at1qx
      author: Bielicki, Julia A
       title: Monitoring approaches for health-care workers during the COVID-19 pandemic
        date: 2020-07-23
       words: 4878
      flesch: 31
     summary: The art of war in the era of coronavirus disease 2019 (COVID-19) Intensive care during the coronavirus epidemic Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations Escalating infection control response to the rapidly evolving epidemiology of the coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in Hong Kong Contact tracing: public health management of persons, including healthcare workers, having had contact with COVID-19 cases in the European Union COVID-19) pandemic: increased transmission in the EU/EEA and the UK-sixth update Health workers exposure risk assessment and management in the context of COVID-19 virus Interim US guidance for risk assessment and public health management of healthcare personnel with potential exposure in a healthcare setting to patients with coronavirus disease (COVID-19) Health workforce development in the European Union: a matrix for comparing trajectories of change in the professions Risks to healthcare workers with emerging diseases: lessons from MERS-CoV, Ebola, SARS, and avian flu Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures Clinical characteristics of 138 hospitalised patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Characteristics of health care personnel with COVID-19-United States Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Death from COVID-19 of 23 health care workers in China Epidemia COVID-19-aggiornamento nazionale Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed Protecting health care workers during the coronavirus disease 2019 (COVID-19) outbreak: lessons from Taiwan's severe acute respiratory syndrome response Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staff Protecting Chinese healthcare workers while combating the 2019 novel coronavirus Protecting health-care workers from subclinical coronavirus infection Temporal dynamics in viral shedding and transmissibility of COVID-19 Epidemiology of COVID-19 in a long-term care facility in King County, Washington Beyond the assistance: additional exposure situations to COVID-19 for healthcare workers COVID-19 in Australian healthcare workers: early experience of the Royal Melbourne Hospital emphasises the importance of community acquisition Epidemiological, clinical characteristics and outcome of medical staff infected with COVID-19 in Wuhan, China: a retrospective case series analysis Epidemiology of and risk factors for coronavirus infection in health care workers: a living rapid review COVID-19 in healthcare workers in three hospitals in the south of the Netherlands Rapid assessment of regional SARS-CoV-2 community transmission through a convenience sample of healthcare workers, the Netherlands Kontaktpersonennachverfolgung bei respiratorischen Erkrankungen durch das Coronavirus SARS-CoV-2 Risk assessment of healthcare workers with potential workplace exposure to COVID-19 case (V8.1) Public health management of cases and contacts associated with coronavirus disease Medical masks vs N95 respirators for preventing COVID-19 in health care workers: a systematic review and meta-analysis of randomised trials A systematic risk-based strategy to select personal protective equipment for infectious diseases Risk of nosocomial transmission of coronavirus disease 2019: an experience in a general ward setting in Hong Kong Asymptomatic and presymptomatic SARS-CoV-2 infections in residents of a longterm care skilled nursing facility Diagnosis and clinical management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: an operational recommendation of Peking Union Medical College Hospital (V2.0) Community transmission of SARS-CoV-2 is targeted by public health measures, whereas infection by patient or health-care worker contact is primarily addressed by facility-based infection prevention and control (IPC) measures.
    keywords: care; cov-2; covid-19; health; infection; risk; sars; testing; workers
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        item: #4928 of 7819
          id: cord-317811-mxsujb5u
      author: Migliaccio, Raffaella
       title: Dementia and COVID-19 Lockdown: More Than a Double Blow for Patients and Caregivers
        date: 2020-07-06
       words: 2661
      flesch: 52
     summary: This huge modification in everyday life, associated with the inability of dementia patients to manage the present situation, makes these current times hugely demanding for patients and their families. This could involve reducing the number of patients per care unit and the number of healthcare professionals per patient, as well as the implementation of technology to maintain contact with the outside world.
    keywords: caregivers; covid-19; dementia; health; pandemic; patients
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        item: #4929 of 7819
          id: cord-317820-od9l7p1r
      author: Goker Bagca, Bakiye
       title: Overview of the COVID-19 and JAK/STAT Pathway Inhibition: Ruxolitinib Perspective
        date: 2020-06-20
       words: 3967
      flesch: 35
     summary: The possible targets of ruxolitinib are determined by using genetic alterations that have been reported in COVID-19 patients. To determine the potential molecular efficacy of ruxolitinib on genetic alterations determined in various tissues and blood levels of COVID-19 patients, JAK1 and JAK2 by using The STRING Database Version 11.
    keywords: cells; cov-2; covid-19; cytokine; immune; jak; pathway; patients; ruxolitinib; sars; treatment; virus
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        item: #4930 of 7819
          id: cord-317822-e4uhop4w
      author: Bahrami, Ahmad
       title: Hyperinflammatory shock related to COVID‐19 in a patient presenting with multisystem inflammatory syndrome in children: First case from Iran
        date: 2020-07-08
       words: 1865
      flesch: 46
     summary: Royal College of Paediatrics and Child Health COVID-19 and Kawasaki disease: Novel virus and novel case An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: An observational cohort study Concurrent respiratory viruses and Kawasaki disease Complex immune dysregulation in COVID-19 patients with severe respiratory failure We would like to thank both our patient and her family for letting us share their experience. According to previous studies, the most common viruses detected in KD patients were rhinovirus and enterovirus.
    keywords: cases; covid-19; mis; patient; shock
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        item: #4931 of 7819
          id: cord-317823-ztawznod
      author: Yehya, Nadir
       title: Statewide Interventions and Covid-19 Mortality in the United States: An Observational Study
        date: 2020-07-08
       words: 3515
      flesch: 47
     summary: Historical analysis of the 1918-1919 influenza pandemic during the second wave of infections that examined 43 cities in the United States demonstrated an association between earlier school closures and bans on public gatherings with lower mortality Emergency declarations and school closures were two early statewide interventions.
    keywords: day; emergency; mortality; school; states
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        item: #4932 of 7819
          id: cord-317834-5givph12
      author: Bhat, Kulthe Ramesh Seetharam
       title: COVID-19 model-based practice changes in managing a large prostate cancer practice: following the trends during a month-long ordeal
        date: 2020-06-14
       words: 3157
      flesch: 54
     summary: For example, in Papa Giovanni XXIII Hospital in Lombardy, where the COVID-19 incidence was high, all of the urologic procedures were suspended on the 19th of March due to the following reasons: (I) lack of anaesthesiologists, (II) use of beds and wards by COVID-19 patients, (III) diversion of urology staff to care for COVID-19 patients and (IV) risk of infecting non-COVID-19 patients with the virus [12] . This is especially important when it comes to dealing with the treatment of cancer patients.
    keywords: cancer; covid-19; new; pandemic; patients; practice; risk
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        item: #4933 of 7819
          id: cord-317843-sp4nvbbh
      author: Azuma, Kenichi
       title: Impact of climate and ambient air pollution on the epidemic growth during COVID-19 outbreak in Japan
        date: 2020-08-12
       words: 1405
      flesch: 48
     summary: This includes population, 5 percentage of inhabitants aged ≥65 years, total land surface area (km 2 ), inhabitable area 6 (km 2 ), taxable income, tax debtor, life expectancy at birth (MIAC, 2019), and health 7 expenditure (Cabinet Office, 2020). We determined the association of epidemic growth with exposure variables using 9 univariate and multivariable analyses for 28 geographical areas, divided to five periods 10 from March 13 to April 6, 2020 with a longitudinal manner.
    keywords: covid-19; date; mean; temperature
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        item: #4934 of 7819
          id: cord-317846-str9i01o
      author: Chen, Dr. Xian
       title: Mesenchymal stem cell therapy in severe COVID-19: a retrospective study of short-term treatment efficacy and side effects
        date: 2020-05-15
       words: 1114
      flesch: 54
     summary: key: cord-317846-str9i01o authors: Chen, Dr. Xian; Shan, Yuheng title: Mesenchymal stem cell therapy in severe COVID-19: a retrospective study of short-term treatment efficacy and side effects date: 2020-05-15 journal: J Infect DOI: 10.1016/j.jinf.2020.05.020 sha: doc_id: 317846 cord_uid: str9i01o nan We read with interest the recent paper by Cantini et al., describing the safety and clinical impact of baricitinib therapy in Coronavirus disease 2019 (COVID-19) Hence, MSCs therapy may be a promising option for the treatment of severe COVID-19.
    keywords: covid-19; mscs; therapy
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        item: #4935 of 7819
          id: cord-317849-i80zf67c
      author: Isautier, J. M.
       title: Lessons from the COVID-19 pandemic: People's experiences and satisfaction with telehealth during the COVID-19 pandemic in Australia
        date: 2020-09-11
       words: 4237
      flesch: 45
     summary: Future studies should investigate whether patients who are cancelling or postponing health appointments are seeking telehealth services and monitor the long-term impact of health service utilization on health outcomes Whilst the study sample was large and diverse, it is not statistically representative of the Australian population, in particular including a higher proportion of females, a higher level of education, and potentially higher levels of digital literacy. Multivariable^ analysis of factors associated with poorer % telehealth experience compared to in-person appointment (n=574).
    keywords: covid-19; experience; license; pandemic; person; preprint; telehealth
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        item: #4936 of 7819
          id: cord-317859-afvi0g0a
      author: Wilson, Mathew G
       title: Cardiorespiratory considerations for return-to-play in elite athletes after COVID-19 infection: a practical guide for sport and exercise medicine physicians
        date: 2020-09-02
       words: 3542
      flesch: 33
     summary: In those athletes who report COVID-19 related respiratory symptoms that are persistent and taking longer than 14 days to recover, we recommend a thorough assessment to exclude the presence of thromboembolic events, ongoing intrapulmonary pathology or cardiac injury. There are now consistent reports that COVID-19 positive athletes may present persistent and residual symptoms many weeks to months after initial infection, including cough, tachycardia and extreme fatigue.
    keywords: athletes; cardiac; covid-19; exercise; infection; patients; pulmonary; rtp; symptoms
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        item: #4937 of 7819
          id: cord-317863-xf0bn3cv
      author: Pata, Ramakanth
       title: Probability of COVID-19 Being the Culprit in Neurocognitive Deception: A Case Series of Incidental Strokes in ICU Patients With COVID-19
        date: 2020-08-18
       words: 2205
      flesch: 45
     summary: Moreover, high levels of thrombosis and inflammatory serum markers, such as D-dimer, fibrinogen, and CRP, have been seen in COVID-19 patients. Other case reports have also demonstrated evidence of coagulopathy and antiphospholipid antibodies in COVID-19 patients who developed ischemic strokes.
    keywords: april; covid-19; figure; patients; sars; stroke
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        item: #4938 of 7819
          id: cord-317878-bqpj0ey0
      author: Czick, Maureen
       title: COVID’s Razor: RAS Imbalance, the Common Denominator Across Disparate, Unexpected Aspects of COVID-19
        date: 2020-09-11
       words: 12687
      flesch: 39
     summary: 7 Journalists warned as COVID-19 patients developed renal failure requiring dialysis, 8 and obesity was linked to higher mortality. Many hospitalized COVID-19 patients reportedly display silent hypoxia: severe arterial hypoxemia without evident dyspnea, air hunger, or breathlessness.
    keywords: ace; ace2; aceis; african; aii; angiotensin; angiotensin system; arbs; at1; at2; blood; cells; converting; covid-19; disease; effects; enzyme; expression; hypertension; levels; patients; ras; receptor; renin; system; tissue; vascular
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        item: #4939 of 7819
          id: cord-317906-u5z5cpfk
      author: Gupta, Ishita
       title: Atypical Neurological Manifestations of COVID-19
        date: 2020-06-08
       words: 2189
      flesch: 57
     summary: A novel syndrome Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study Self-reported olfactory and taste disorders in patients with severe acute respiratory coronavirus 2 infection: a cross-sectional study A first case of meningitis/encephalitis associated with SARS-Coronavirus-2 COVID-19-associated acute hemorrhagic necrotizing encephalopathy: CT and MRI features Guillain-Barre syndrome associated with SARS-CoV-2 infection: causality or coincidence Sudden and complete olfactory loss function as a possible symptom of COVID-19 Hearing loss and COVID-19: a note Characteristics of ocular findings of patients with coronavirus disease 2019 (COVID-19 Alterations in smell or taste in mildly symptomatic outpatients with SARS-CoV-2 infection COVID-19 may induce Guillain-Barre syndrome Guillain-Barré syndrome following COVID-19: new infection, old complication Neurologic manifestations in an infant with COVID-19 Meningoencephalitis without respiratory failure in a young female patient with COVID-19 infection in Downtown Los Angeles, early April Concomitant neurological symptoms observed in a patient diagnosed with coronavirus disease 2019 Acute-onset smell and taste disorders in the context of Covid-19: a pilot multicenter PCR-based case-control study Guillain Barre syndrome associated with COVID-19 infection: a case report Miller Fisher syndrome and polyneuritis cranialis in COVID-19 The Springer Index of Viruses The Springer Index of Viruses Family -Coronaviridae. This study did not require ethical approval as data was obtained from already available databases, and patients were not directly involved.
    keywords: coronavirus; cov-2; covid-19; patients; sars; symptoms
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        item: #4940 of 7819
          id: cord-317952-4oa9hfb4
      author: Bourgonje, Arno R.
       title: Angiotensin‐converting enzyme‐2 (ACE2), SARS‐CoV‐2 and pathophysiology of coronavirus disease 2019 (COVID‐19)
        date: 2020-05-17
       words: 12115
      flesch: 33
     summary: Safety concerns of clinical images and skin biopsies Urticarial eruption in COVID-19 infection A case of COVID-19 pneumonia in a young male with full body rash as a presenting symptom Reply to COVID-19 can present with a rash and be mistaken for Dengue: Petechial rash in a patient with COVID-19 infection COVID-19 can present with a rash and be mistaken for Dengue Immune thrombocytopenic purpura in a patient with Covid-19 A distinctive skin rash associated with Coronavirus Disease Cutaneous manifestations in COVID-19: a first perspective Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study A case report of neonatal COVID-19 infection in China Novel coronavirus infection and pregnancy Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn Unlikely SARS-CoV-2 vertical transmission from mother to child: A case report Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China Vertical transmission of coronavirus disease 2019 (COVID-19) from infected pregnant mothers to neonates: Possible explanations of male predominance among COVID-19 patients may be differences in exposure, smoking behaviour, other lifestyle factors, differences in chromosomal ACE2 expression, ACE2 expression in testicular tissue, sex hormone-driven immune system regulation, or gender differences in RAAS regulation [37, [42]
    keywords: ace2; acute; angiotensin; article; cells; clinical; copyright; coronavirus; cov-2; covid-19; disease; expression; human; immune; infection; injury; patients; potential; rights; role; sars; study; treatment
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        item: #4941 of 7819
          id: cord-317956-srbualjc
      author: Klang, Eyal
       title: Sex Differences in Age and Comorbidities for COVID-19 Mortality in Urban New York City
        date: 2020-08-09
       words: 1522
      flesch: 53
     summary: The link between gender and the severity of COVID-19 disease is still not completely understood. The model was adjusted for age and comorbidities known to be associated with COVID-19 mortality.
    keywords: age; covid-19; patients; women
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        item: #4942 of 7819
          id: cord-317966-ut6tzc8s
      author: Kocak, Burak
       title: A Case Report of Oligosymptomatic Kidney Transplant Patients with COVID-19: Do They Pose a Risk to Other Recipients?
        date: 2020-05-15
       words: 2114
      flesch: 42
     summary: Thus, kidney transplant patients who are on steroids and other immunosuppressive drugs may exhibit unusual clinical courses resulting from coronavirus infection. It is a well-known entity that viral infections may cause atypical symptoms and signs in transplant patients due to the chronic immunosuppression.
    keywords: coronavirus; covid-19; disease; home; patients; transplant
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        item: #4943 of 7819
          id: cord-317988-1buh1wm0
      author: Kalichman, Seth C.
       title: Intersecting Pandemics: Impact of SARS-CoV-2 (COVID-19) Protective Behaviors on People Living With HIV, Atlanta, Georgia
        date: 2020-06-05
       words: 4049
      flesch: 40
     summary: We conducted a rapid-response interview to assess COVID-19 protective behaviors of people living with HIV and the impact of their responses on HIV-related health care. 16, 17 The increased vulnerability for COVID-19 severity in people living with HIV shines a light on the necessity of adopting COVID-19 protective behaviors, avoiding public gatherings, reducing social contacts, and physical distancing.
    keywords: adherence; behaviors; care; covid-19; food; health; hiv; participants; people; use
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        item: #4944 of 7819
          id: cord-317990-61is0hgm
      author: Quinn, Katherine G.
       title: Applying the Popular Opinion Leader Intervention for HIV to COVID-19
        date: 2020-06-25
       words: 2199
      flesch: 31
     summary: Accordingly, we can take lessons learned from the HIV epidemic about the spread of public health information and its effects on behavior change apply them to the current pandemic. Stigma resulting from xenophobia or racism can limit access to accurate public health information, alienate communities from needed prevention and treatment resources, and further contribute to disparities in disease outcomes
    keywords: covid-19; health; hiv; men; public; social
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        item: #4945 of 7819
          id: cord-318018-ybdkp398
      author: Bruni, Margherita
       title: Persistence of Anti-SARS-CoV-2 Antibodies in Non-Hospitalized COVID-19 Convalescent Health Care Workers
        date: 2020-10-01
       words: 5489
      flesch: 37
     summary: The presence of few false positives among the COVID-negative population tested with the viral nucleocapsid protein as compared to the RBD might be a consequence of a mistakenly detection of anti-N antibodies previously raised against common cold coronaviruses which cross-react with the SARS-CoV-2 nucleocapsid [23] . On the contrary, even in the early convalescent phase, those cytokines were undetectable in the sera of non-hospitalized COVID-19 patients (Figure 2A) .
    keywords: antibodies; antibody; cov-2; covid-19; figure; infection; patients; protein; rbd; sars; sera; spike
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        item: #4946 of 7819
          id: cord-318029-xd7nuahh
      author: Ke, Chunjin
       title: 2019 novel coronavirus disease (COVID-19) in hemodialysis patients: a report of two cases
        date: 2020-04-30
       words: 1098
      flesch: 39
     summary: A Novel Coronavirus from Patients with Pneumonia in China Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia The Novel Coronavirus: A Bird's Eye View Emerging coronaviruses: Genome structure, replication Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice Toll-Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia Proliferative growth of SARS coronavirus in Vero E6 cells Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling Interferon and cytokine responses to SARS-coronavirus infection Correlation Analysis Between disease severity and inflammation-related parameters in patients with COVID-19 pneumonia The removal of cytokines through blood purification technology may be beneficial for the recovery of COVID-19 patients.
    keywords: coronavirus; covid-19; patients; pneumonia
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        item: #4947 of 7819
          id: cord-318032-d9dnugod
      author: Ali Hassan, Syed M.
       title: Improved safety of endoscopic vessel harvesting during the COVID-19 pandemic
        date: 2020-06-03
       words: 1151
      flesch: 38
     summary: We present the use of a non-sealed endoscopic vessel harvesting(EVH) approach during coronary surgery that does not necessitate the use of CO2 insufflation and utilizes suction through an ultra low particulate filter, thus mitigating the risk of possible viral transmission via aerosolization or surgical smoke production. We present the use of a non-sealed endoscopic vessel harvesting(EVH) approach during coronary surgery that does not necessitate the use of CO2 insufflation and utilizes suction through an ultra low particulate filter, thus mitigating the risk of possible viral transmission via aerosolization or surgical smoke production.
    keywords: aerosolization; risk; transmission
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        item: #4948 of 7819
          id: cord-318038-psultpzy
      author: José Concepción Zavaleta, Marcio
       title: Diabetic ketoacidosis during COVID-19 pandemic in a developing country
        date: 2020-08-25
       words: 547
      flesch: 45
     summary: This damage can be expressed by an elevation of pancreatic enzyme levels in patients with COVID-19 This is also happening in developing countries such as Peru, which has the highest number of COVID-19 cases per million inhabitants and the second-lowest public healthcare spending according to WHO [2] .
    keywords: diabetes; patients
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        item: #4949 of 7819
          id: cord-318043-1x3dp1vv
      author: Ahmadi, Mohsen
       title: Investigation of effective climatology parameters on COVID-19 outbreak in Iran
        date: 2020-04-17
       words: 2140
      flesch: 48
     summary: The higher value of the population density and intra-provincial movement leads to a higher value of infection rate so that in high-density provinces, the rate of disease growth reaches 150 people per day. In this study, the correlation of nine main variables includes the number of infected people, population density, intra-provincial movement, days of infection, average temperature, average rain, humidity, wind speed, and solar radiation with infection rate analyzed.
    keywords: covid-19; density; infection; iran; rate
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        item: #4950 of 7819
          id: cord-318044-podm4mjd
      author: Wu, P.
       title: The Trans-omics Landscape of COVID-19
        date: 2020-07-22
       words: 4704
      flesch: 35
     summary: These results demonstrated that our model could not 373 only be employed to stratify COVID-19 patients, but also discover molecular associated 374 with pathogenesis of COVID-19. To the best 381 of our knowledge, this is the first trial designed to systematically analyze trans-omics 382 data of COVID-19 patients with grade of clinical severity.
    keywords: analysis; asymptomatic; covid-19; data; disease; expression; figure; model; omics; patients; severity
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        item: #4951 of 7819
          id: cord-318067-4hdeuweo
      author: Torrego, Alfons
       title: Bronchoscopy in Patients with COVID-19 with Invasive Mechanical Ventilation: A Single-Center Experience
        date: 2020-07-15
       words: 1887
      flesch: 37
     summary: Some authors have regularly reported from their clinical experience that the key feature of COVID-19 respiratory mechanics would be an uncommon association of severe hypoxemia and preserved respiratory system compliance, altogether with poor recruitability (3) (4) (5) . key: cord-318067-4hdeuweo authors: Torrego, Alfons; Pajares, Virginia; Fernández-Arias, Carmen; Vera, Paula; Mancebo, Jordi title: Bronchoscopy in Patients with COVID-19 with Invasive Mechanical Ventilation: A Single-Center Experience date: 2020-07-15 journal: Am J Respir Crit Care Med DOI: 10.1164/rccm.202004-0945le sha: doc_id: 318067 cord_uid: 4hdeuweo nan To the Editor: Severe coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to acute respiratory distress syndrome and hypoxemic respiratory failure (1) .
    keywords: ards; bronchoscopy; covid-19; data; patients
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        item: #4952 of 7819
          id: cord-318068-3mnhd56l
      author: Tan, Hanno L
       title: How does COVID-19 kill at home and what should we do about it?
        date: 2020-08-21
       words: 1858
      flesch: 36
     summary: One important limitation is, however, that both registries only enrol OHCA patients with EMS involvement. However, the number of OHCA patients with analysable post-ROSC ECGs was small (n = 18, including six with COVID-19).
    keywords: cardiac; covid-19; incidence; ohca; patients
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        item: #4953 of 7819
          id: cord-318116-u0swlpug
      author: Dolores García-Cosío, M.
       title: Trasplante cardiaco durante la pandemia por coronavirus: organización asistencial y características de los pacientes infectados
        date: 2020-10-05
       words: 1367
      flesch: 41
     summary: Todo el personal del AI recibió una formación intensiva en cuanto a los procedimientos de aislamiento de los pacientes, manejo del equipo de protección individual y esterilización sistemática. key: cord-318116-u0swlpug authors: Dolores García-Cosío, M.; Hernán, Marta Flores; Pérez, Pedro Caravaca; López-Medrano, Francisco; Arribas, Fernando; Jiménez, Juan Delgado title: Trasplante cardiaco durante la pandemia por coronavirus: organización asistencial y características de los pacientes infectados date: 2020-10-05 journal: Rev Esp Cardiol DOI: 10.1016/j.recesp.2020.08.019 sha: doc_id: 318116 cord_uid: u0swlpug nan Carta científica Trasplante cardiaco durante la pandemia por coronavirus: organización asistencial y características de los pacientes infectados En diciembre de 2019 se describió por primera vez en China un nuevo síndrome de dificultad respiratoria aguda grave, y poco después se identificó un nuevo coronavirus como causa de lo que en la actualidad se denomina enfermedad por coronavirus de 2019 (COVID-19) 1,2 .
    keywords: con; covid-19; del; los; pacientes; para; que
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        item: #4954 of 7819
          id: cord-318167-b25g6zkp
      author: Einollahi, Behzad
       title: A patient affected by critical COVID-19 pneumonia, successfully treated with convalescent plasma
        date: 2020-11-05
       words: 1573
      flesch: 36
     summary: Prolonged viral shedding in a lymphoma patient with COVID-19 infection receiving convalescent plasma Convalescent (immune) plasma treatment in a myelodysplastic COVID-19 patient with disseminated tuberculosis Convalescent plasma: new evidence for an old therapeutic tool? Potential interventions for novel coronavirus in China: a systematic review Hypothesis to explain the severe form of COVID-19 in Northern Italy Use of convalescent plasma therapy in SARS patients in Hong Kong Retrospective comparison of convalescent plasma with continuing highdose methylprednisolone treatment in SARS patients Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocol Effectiveness of convalescent plasma therapy in severe COVID-19 patients Convalescent plasma as a potential therapy for COVID-19 Treatment of 5 critically ill patients with COVID-19 with convalescent plasma Low Dose Radiation Therapy and Convalescent Plasma: How a Hybrid Method May Maximize Benefits for COVID-19 Patients Treatment with convalescent plasma for COVID-19 patients in Wuhan Successful treatment with plasma exchange followed by intravenous immunoglobulin in a critically ill patient with COVID-19 Therapeutic plasma exchange in adults with severe COVID-19 infection Clinical efficacy of convalescent plasma for treatment of COVID-19 infections: Results of a multicenter clinical study Current studies of convalescent plasma therapy for COVID-19 may underestimate risk of antibody-dependent enhancement Early Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease COVID-19 convalescent plasma transfusion Thanks to guidance and advice from Clinical Research Development Unit of Baqiyatallah Hospital J o u r n a l P r e -p r o o f All authors contributed equally to the drafting ,designing and writing of the manuscript and provided critical revision. As the primary immune response arises after 10-14 days since viral infection, CP is more beneficial if administered as soon as possible in COVID-19 patients affected by ARDS and multi-organ disease syndrome, not later than 14 days since symptoms onset [15, 19, 20] .
    keywords: convalescent; covid-19; patient; plasma; therapy
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        item: #4955 of 7819
          id: cord-318178-l17u9oqp
      author: Omura, Takuya
       title: Geriatric practice during and after the COVID‐19 pandemic
        date: 2020-06-09
       words: 883
      flesch: 44
     summary: Although the long-term effects of COVID-19 infection on humans are unclear, the potential effects of excessive cytokines have been reported; inflammatory cytokines can cause frailty, 5 cognitive deterioration 6 and cardiovascular disease. key: cord-318178-l17u9oqp authors: Omura, Takuya; Araki, Atsushi; Shigemoto, Kazuhiro; Toba, Kenji title: Geriatric practice during and after the COVID‐19 pandemic date: 2020-06-09 journal: Geriatr Gerontol Int DOI: 10.1111/ggi.13958 sha: doc_id: 318178 cord_uid: l17u9oqp nan Dear Editor, Two aspects warrant consideration regarding the ongoing COVID-19 pandemic: prevention of COVID-19 infection and protection from the related changes among the elderly.
    keywords: covid-19; frailty; pandemic
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        item: #4956 of 7819
          id: cord-318184-atlslk0e
      author: Germain, N.
       title: Retrospective study of COVID-19 seroprevalence among tissue donors at the onset of the outbreak before implementation of strict lockdown measures in France
        date: 2020-09-11
       words: 2384
      flesch: 46
     summary: We assessed COVID-19 seroprevalence in a population of tissue donors, at the onset of the outbreak in France, before systematic screening of donors for SARS-CoV-2 RNA. The incertitude about transmission risk via tissue donors is increased by the fact that in most cases, (over 80% of cases) donors are asymptomatic or present with very little symptoms 6 .
    keywords: cov-2; donors; medrxiv; preprint; sars
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        item: #4957 of 7819
          id: cord-318194-m4vu77v6
      author: Rentsch, Christopher T.
       title: Patterns of COVID-19 testing and mortality by race and ethnicity among United States veterans: A nationwide cohort study
        date: 2020-09-22
       words: 5474
      flesch: 40
     summary: Unlike other nationwide healthcare systems, linkage to COVID-19 testing data or outcomes was not required as the integrated nature of VA healthcare provided at over 1,200 sites allows all information to be stored in its Corporate Data Warehouse. key: cord-318194-m4vu77v6 authors: Rentsch, Christopher T.; Kidwai-Khan, Farah; Tate, Janet P.; Park, Lesley S.; King, Joseph T.; Skanderson, Melissa; Hauser, Ronald G.; Schultze, Anna; Jarvis, Christopher I.; Holodniy, Mark; Lo Re, Vincent; Akgün, Kathleen M.; Crothers, Kristina; Taddei, Tamar H.; Freiberg, Matthew S.; Justice, Amy C. title: Patterns of COVID-19 testing and mortality by race and ethnicity among United States veterans: A nationwide cohort study date: 2020-09-22 journal: PLoS Med DOI: 10.1371/journal.pmed.1003379 sha: doc_id: 318194 cord_uid: m4vu77v6 BACKGROUND: There is growing concern that racial and ethnic minority communities around the world are experiencing a disproportionate burden of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19).
    keywords: black; care; covid-19; disparities; health; hispanic; individuals; mortality; racial; testing
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        item: #4958 of 7819
          id: cord-318204-t024w7h6
      author: Fang, Ferric C
       title: The Laboratory Diagnosis of COVID-19-- Frequently-Asked Questions
        date: 2020-06-08
       words: 2982
      flesch: 34
     summary: The role of antibody testing for SARS-CoV-2: Is there one? Severe acute respiratory syndrome coronavirus 2-specific antibody responses in coronavirus disease Test performance evaluation of SARS-CoV-2 serological assays Evaluation of nine commercial SARS-CoV-2 immunoassays Patients with common cold coronavirusaes tested negative for IgG antibody to SARS-CoV-2 Validation and performance comparison of three SARS-CoV-2 antibody assays A systematic review of antibody mediated immunity to coronaviruses: antibody kinetics, correlates of protection, and association of of disease Profiling early humoral response to diagnose novel coronavirus disease (COVID-19) Early detection of SARS-CoV-2 antibodies in COVID-19 patients as a serologic marker of infection Longitudinal change of SARS-Cov2 antibodies in patients with COVID-19 Different longitudinal patterns of nucleic acid and serology testing results based on disease severity of COVID-19 patients COVID-19 and postinfection immunity: Limited Evidence, Many Remaining Questions SARS-CoV-2 infection protects against rechallenge in Rhesus Macaques Convalescent plasma in Covid-19: Possible mechanisms of action Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals Laboratory diagnosis of emerging human coronavirus infections -the state of the art Point-of-care testing for COVID-19 using SHERLOCK diagnostics Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19 Interpreting diagnostic tests for SARS-CoV-2 A c c e p t e d M a n u s c r i p t 15 Cross-reactivity between SARS-CoV-1 or MERS-CoV and SARS-CoV-2 is more likely (56) , but should be a limited concern.
    keywords: cov-2; covid-19; patients; sars
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        item: #4959 of 7819
          id: cord-318262-w8oixzdg
      author: Chevance, A
       title: Ensuring mental health care during the SARS-CoV-2 epidemic in France: a narrative review
        date: 2020-04-22
       words: 6753
      flesch: 33
     summary: To date, there is no structured data available on the epidemiology, clinical presentation and prognosis of psychiatric patients with COVID-19. This organization remains tenable because for the moment Ensuring the follow-up of psychiatric patients in a forced ambulatory situation.
    keywords: care; confinement; context; covid-19; disorders; epidemic; health; hospital; measures; medical; patients; people; population; psychiatric; risk
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        item: #4960 of 7819
          id: cord-318312-v1c3qm7h
      author: Fischer, Quentin
       title: Case report of anterior ST-elevation myocardial infarction in a patient with coronavirus disease-2019
        date: 2020-05-19
       words: 1645
      flesch: 39
     summary: While the general management of ACS has been well-defined in international guidelines, reports of ACS in COVID-19 patients are scarce, and there is no clear recommendation as regard to optimal treatment in such patients. Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic COVID-19 and the cardiovascular system Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study How to balance acute myocardial infarction and COVID-19: the protocols from Sichuan Provincial People's Hospital Case report of anterior STEMI in a patient with COVID-19
    keywords: covid-19; elevation; infarction; patient
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        item: #4961 of 7819
          id: cord-318316-9unfl966
      author: Ortega, Joseph T.
       title: Understanding Severe Acute Respiratory Syndrome Coronavirus 2 Replication to Design Efficient Drug Combination Therapies
        date: 2020-10-23
       words: 4027
      flesch: 42
     summary: The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19? Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor A human monoclonal antibody blocking SARS-CoV-2 infection The antiviral facet of anti-rheumatic drugs: lessons from COVID-19 Effect of bromhexine on clinical outcomes and mortality in COVID-19 patients: a randomized clinical trial Evidence that TM-PRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response Race to find CO-VID-19 treatments accelerates Chloroquine does not inhibit infection of human lung cells with SARS-CoV-2 Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma COVID-19, an emerging coronavirus infection: advances and prospects in designing and developing vaccines, immunotherapeutics, and therapeutics Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro A systematic review of lopinavir therapy for SARS coronavirus and MERS coronavirus -a possible reference for coronavirus disease-19 treatment option DrugBank 5.0: a major update to the DrugBank database for 2018 Effect of systemic inflammatory response to SARS-CoV-2 on lopinavir and hydroxychloroquine plasma concentrations. Three major targets have been identified and can be summarized in the following: early stages of virus-cell interaction, viral proteases, and the viral RNA-dependent RNA polymerase (RdRp)
    keywords: antiviral; coronavirus; cov-2; covid-19; drug; infection; protease; sars; therapy
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        item: #4962 of 7819
          id: cord-318317-x12fblc5
      author: Sagaon-Teyssier, Luis
       title: The COVID-19 response must integrate people living with HIV needs in Sub-Saharan Africa: the case of Mali
        date: 2020-06-03
       words: 1360
      flesch: 44
     summary: For Mali, data on daily COVID-19 cases were obtained from the official communiqués from the Ministry of Health and Social Affairs (data updated May 6, 2020) http://www.sante.gov.ml/index.php/actualites. RAND Corporation Is Sub-Saharan Africa prepared for COVID-19 Actions pour la Prévention et la Réponse à la Maladie à COVID-19 (COVID-19) COVID-19: a potential public health problem for homeless populations Preparedness is essential for malaria-endemic regions during the COVID-19 pandemic Le coronavirus en Afrique « est en train de se diffuser de façon massive Quick community survey on the impact of COVID-19 outbreak for the healthcare of people living with HIV Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019 COVID-19: protecting health-care workers Editorial: Managing the march of COVID-19: lessons from the HIV and AIDS epidemic Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
    keywords: cases; covid-19; mali; march
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        item: #4963 of 7819
          id: cord-318319-efqf5e1i
      author: Yamasaki, Yukitaka
       title: The peripheral lymphocyte count as a predictor of severe COVID-19 and the effect of treatment with ciclesonide
        date: 2020-07-03
       words: 2137
      flesch: 54
     summary: Of the 30 included patients, 12, 14, and 4 were allocated to severe pneumonia, non-severe pneumonia, and non-pneumonia groups, respectively. Patients were divided into three groups: severe pneumonia, non-severe pneumonia, and non-pneumonia.
    keywords: covid-19; group; non; patients; pneumonia
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        item: #4964 of 7819
          id: cord-318321-jfpbkntx
      author: Parashar, Bhupesh
       title: Disease Site-Specific Guidelines for Curative Radiation Treatment During ‘Limited Surgery’ and ‘Hospital Avoidance’: A Radiation Oncology Perspective From the Epicenter of COVID-19 Pandemic
        date: 2020-05-18
       words: 5930
      flesch: 44
     summary: Hospital resources are in such high demand for COVID-19 patients that procedures, such as surgery, dentistry, interventional radiology, and other ancillary services, are not available for cancer patients. In this review, we discuss radiation therapy (RT) options for cancer patients in three settings: 1) RT as an alternative to surgery when immediate surgery is not possible, 2) RT as a 'bridge' to surgery and 3), radiation options definitively or postoperatively, given the risk of hospitalization with high-dose chemotherapy.
    keywords: cancer; chemotherapy; covid-19; dose; fractions; pandemic; patients; radiation; risk; surgery
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        item: #4965 of 7819
          id: cord-318324-cc6rn95z
      author: Handu, Deepa
       title: Malnutrition Care during the COVID-19 Pandemic: Considerations for Registered Dietitian Nutritionists Evidence Analysis Center
        date: 2020-05-14
       words: 2881
      flesch: 37
     summary: Hence, nutrition care to identify and address malnutrition is critical in treating and preventing further adverse health outcomes from COVID-19 infection. Individuals who have multiple comorbidities, are older adults, or who are malnourished are at increased risk of being admitted to the intensive care unit and of mortality from COVID-19 infections.
    keywords: academy; care; covid-19; feeding; food; intake; malnutrition; nutrition
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        item: #4966 of 7819
          id: cord-318326-q9fnbg8n
      author: Cacciapuoti, Sara
       title: Immunocytometric analysis of COVID patients: A contribution to personalized therapy?
        date: 2020-08-29
       words: 3566
      flesch: 42
     summary: Such reduction involves B and T lymphocytes, both reduced in about a half of COVID patients, differently from previous studies that reported a main reduction of T lymphocytes [3, 26] and an increase of the percentage and of the absolute number of B lymphocytes, particularly in severe COVID patients [6] . key: cord-318326-q9fnbg8n authors: Cacciapuoti, Sara; De Rosa, Annunziata; Gelzo, Monica; Megna, Matteo; Raia, Maddalena; Pinchera, Biagio; Pontarelli, Agostina; Scotto, Riccardo; Scala, Emanuele; Scarano, Francesco; Scalia, Giulia; Castaldo, Giuseppe; Fabbrocini, Gabriella; Gentile, Ivan; Parrella, Roberto title: Immunocytometric analysis of COVID patients: A contribution to personalized therapy? date: 2020-08-29 journal: Life Sci DOI: 10.1016/j.lfs.2020.118355 sha: doc_id: 318326 cord_uid: q9fnbg8n AIMS:
    keywords: covid; covid-19; il-6; lymphocytes; number; patients; serum
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        item: #4967 of 7819
          id: cord-318332-krgsd5z3
      author: Sallam, M.
       title: COVID-19 misinformation: mere harmless delusions or much more? A knowledge and attitude cross-sectional study among the general public residing in Jordan
        date: 2020-07-15
       words: 5166
      flesch: 49
     summary: https://doi.org/10.1101/2020.07.13.20152694 doi: medRxiv preprint COVID-19 is a spiritual divine test showed a lower K-score compared to those who did not hold such a belief (10.1 vs. 10.4, p<0.001; M-W, Figure 3 ). Individuals with a lower socio-economic status showed higher anxiety, lower COVID-19 knowledge and belief in misinformation.
    keywords: anxiety; covid-19; license; medrxiv; medrxiv preprint; participants; preprint; study
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        item: #4968 of 7819
          id: cord-318333-rzhrgp5q
      author: Hou, Jiabao
       title: COVID-19 infection, a potential threat to surgical patients and staff? A retrospective cohort study
        date: 2020-09-03
       words: 3271
      flesch: 41
     summary: Although the SAPS Ⅱ scores in surgical patients with COVID-19 were not higher than that in normal surgical patients, 17 two surgical patients (11.76%) died of COVID-19-associated complications, which was much higher than the reported overall case-fatality rate of 4.3% in COVID-19 patients without surgery 3 and was also higher than the case-fatality rate of 7.9% in noncardiac surgical patients. 20 Interestingly, the numbers, not the distribution, of CD3+ and CD4+ cells in COVID-19 surgical patients were lower than those in mild COVID-19 patients without surgery and were similar to those in severe COVID-19 patients, 21 which meant that COVID-19 seriously inhibited the immune function of T lymphocytes after surgery.
    keywords: covid-19; infection; patients; pneumonia; staff; study; surgery
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        item: #4969 of 7819
          id: cord-318342-eipscagh
      author: Chen, Juan
       title: The Impact of COVID-19 on Blood Glucose: A Systematic Review and Meta-Analysis
        date: 2020-10-05
       words: 3603
      flesch: 43
     summary: This may be one of the reasons that increased blood glucose was observed in COVID-19 patients without a prior history of diabetes (4). It remains unclear regarding the effect of severity of COVID-19 infection on glycemic parameters, including blood glucose and glycated haemoglobinA1c (HbA1c).
    keywords: blood; covid-19; diabetes; glucose; infection; patients; studies
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        item: #4970 of 7819
          id: cord-318355-38x3f3ee
      author: Yang, Yang
       title: Visceral Adiposity and High Intramuscular Fat Deposition Independently Predict Critical Illness in Patients with Sars‐COV‐2
        date: 2020-07-17
       words: 3963
      flesch: 42
     summary: There was a moderate correlation between the value of SMD and age, and high IMF deposition was more common in older patients in our study, but high IMF deposition was still a significant risk factor for critical illness when age was adjusted statistically. Furthermore, visceral adiposity or high IMF deposition increased the risk of mechanical ventilation (p=0.013, p<0.001; respectively).
    keywords: adipose; covid-19; deposition; illness; imf; muscle; patients; tissue; visceral
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        item: #4971 of 7819
          id: cord-318363-1mv5j4w2
      author: Zvolensky, Michael J.
       title: Psychological, addictive, and health behavior implications of the COVID-19 pandemic
        date: 2020-08-27
       words: 15844
      flesch: 26
     summary: Although many of these relations would be expected, theoretically, to be negative, select subgroups will certainly adaptively respond to COVID-19 related stress (e.g., improve their physical fitness, improve self-care routines, quit/reduce maladaptive behaviors that place them at risk). Although this illustrative example represents only one of many possible transdiagnostic amplifying factors, it draws attention to the fact that individual differences in psychological processes are apt to play a central role in the relation between COVID-19 related stress and mental health, addictive behavior, health behavior, and chronic illness.
    keywords: alcohol; anxiety; behavior; cannabis; children; chronic; covid-19; covid-19 pandemic; disease; et al; factors; health; health behavior; hiv; illness; individuals; j o; pandemic; psychological; r n; risk; sleep; smoking; stress; symptoms; treatment; u r; use
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        item: #4972 of 7819
          id: cord-318364-5bmdzgla
      author: Sun, Xinjuan
       title: Cytokine storm intervention in the early stages of COVID-19 pneumonia
        date: 2020-04-25
       words: 3109
      flesch: 25
     summary: Also IL-17 inhibitor (Secukinumab) (Novartis) was used as specific treatment for severe patients with COVID-19 pneumonia 25 to control Th17 cell activation. Continuous renal replacement therapy (CRRT) may benefit severe patients by removing potentially harmful components and maintaining haemodynamic and metabolic status.
    keywords: covid-19; cytokine; disease; infection; patients; pneumonia; sars; syndrome
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        item: #4973 of 7819
          id: cord-318367-8xrjddwy
      author: Liu, Xiucheng
       title: An especial transition phase of hospitals: the adaptation of hospital operations to the development of COVID-19 and policy adjustments
        date: 2020-09-21
       words: 1597
      flesch: 40
     summary: key: cord-318367-8xrjddwy authors: Liu, Xiucheng; Zhuang, Wei; Quan, Xiaoyu; Zhou, Yeqing; Qin, Hao; Zou, Chenghang; Zhang, Hao title: An especial transition phase of hospitals: the adaptation of hospital operations to the development of COVID-19 and policy adjustments date: 2020-09-21 journal: Therefore, gradually promoting hospital operations and functions back to the new normal is important, especially when this outbreak has been effectively controlled.
    keywords: covid-19; epidemic; hospitals; medical; patients
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        item: #4974 of 7819
          id: cord-318369-y3wtfqrn
      author: Pan, Lingai
       title: How to optimize the Radiology protocol during the global COVID-19 epidemic: Keypoints from Sichuan Provincial People's Hospital
        date: 2020-08-05
       words: 1247
      flesch: 48
     summary: One CT machine was arranged in a fixed room only for fever clinic patients .One for emergency patients with or without general respiratory symptoms and two for routine CT(scheduled patients without any respiratory symptoms). In case of clinical suspected patients, launch the MDT consultation, do not miss any suspected patient.
    keywords: covid-19; epidemic; patients; room
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        item: #4975 of 7819
          id: cord-318370-l2fdd4zt
      author: Wittayanakorn, Nunthasiri
       title: COVID-19’s Impact on Neurosurgical Training in Southeast Asia
        date: 2020-08-15
       words: 3218
      flesch: 46
     summary: In this study, we describe the impact of COVID-19 on neurosurgical training in Southeast Asia. Conclusions An effective national strategy to control COVID-19 is crucial to sustain neurosurgical training and to provide essential neurosurgical services.
    keywords: covid-19; neurosurgery; neurosurgical; pandemic; trainees; training; world
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        item: #4976 of 7819
          id: cord-318371-irqked5z
      author: Assandri, Roberto
       title: Laboratory Biomarkers Predicting COVID-19 Severity in the Emergency Room
        date: 2020-05-21
       words: 802
      flesch: 47
     summary: In the following days, the Maggiore Hospital Emergency Unit was invaded by suspected COVID-19 patients. In the first time at the emergency room, a positive Real-Time PCR (RT-PCR) test for SARS-CoV-2 after nasopharyngeal swab was officially considered the hallmark for COVID-19 diagnosis.
    keywords: covid-19; emergency; patients
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        item: #4977 of 7819
          id: cord-318378-omsc9a8k
      author: Chen, Lian
       title: Pregnancy with Covid‐19: Management considerations for care of severe and critically ill cases
        date: 2020-07-04
       words: 3231
      flesch: 43
     summary: Therefore Although, the risk of developing into severe cases in pregnant women with Covid-19 is not higher than that of the general population, the management of severe and critically ill cases still deserves more attention. In the correspondence we published previously, 7 the information of 118 infected pregnant women in Wuhan from the epidemic reporting system of the National Health Commission showed a rate of severe maternal disease at 7.6%.
    keywords: cases; covid-19; delivery; disease; pregnancy; women
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        item: #4978 of 7819
          id: cord-318390-uuz37610
      author: Saleem, Tayyaba
       title: COVID-19 containment and its unrestrained impact on epilepsy management in resource-limited areas of Pakistan
        date: 2020-09-25
       words: 2928
      flesch: 39
     summary: Importantly, epilepsy cases are not uniformly distributed; instead, a large number of patients belong to resource-poor regions [5, 6] , places that are more at risk of epidemic outbreaks, thus making epilepsy management more difficult during an epidemic. key: cord-318390-uuz37610 authors: Saleem, Tayyaba; Sheikh, Nadeem; Abbasi, Muddasir Hassan; Javed, Iram; khawar, Muhammad Babar title: COVID-19 containment and its unrestrained impact on epilepsy management in resource-limited areas of Pakistan date: 2020-09-25 journal: Epilepsy Behav DOI: 10.1016/j.yebeh.2020.107476 sha: doc_id: 318390 cord_uid: uuz37610 The current pandemic of coronavirus disease 2019 (COVID-19) that led to an unprecedented crisis with significant health, social, and economic repercussions presented more serious concerns for those living with some chronic conditions such as epilepsy.
    keywords: covid-19; epilepsy; management; pakistan; pandemic; patients; study
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        item: #4979 of 7819
          id: cord-318391-2s0rjfn8
      author: Akirov, Amit
       title: Tackling Obesity During the COVID‐19 Pandemic
        date: 2020-08-14
       words: 2531
      flesch: 44
     summary: Their study demonstrated a shift in the age threshold of developing severe COVID-19 disease in obese patients, such that severe obesity places young patients in their 30s at a similar risk category as elderly normal weight patients [18] . Obesity has been observed to be associated with severe COVID-19 disease, independent of diabetes, hypertension and cardiovascular disease -concomitant disorders also known to contribute to severe disease [18] .Several potential underlying mechanisms have been proposed.
    keywords: covid-19; diabetes; obese; obesity; patients; risk
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        item: #4980 of 7819
          id: cord-318410-fznw4bbq
      author: Alhazmi, Amani
       title: Knowledge, attitudes and practices among people in Saudi Arabia regarding COVID-19: A cross-sectional study
        date: 2020-09-18
       words: 4288
      flesch: 44
     summary: 13, 14 Therefore, this study aims to obtain useful information about knowledge levels, attitudes, and practices (KAP) towards COVID-19 in the general population. For statistical testing, the frequency and percentage were applied while a t-test and one-way ANOVA were used to test for statistical significance, and the percentage was used to test for statistical significance between study variables; p>0.05 was considered to be statistically significant.
    keywords: arabia; attitude; covid-19; knowledge; participants; practices; saudi; study
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        item: #4981 of 7819
          id: cord-318417-jfqnepzy
      author: Koay, Hui-Fern
       title: An unconventional view of COVID-19 T cell immunity
        date: 2020-10-06
       words: 1535
      flesch: 39
     summary: More nuanced studies are necessary to directly explore the exact contribution of unconventional T cells, which may include COVID-19 animal models (such as humanized ACE2 mice or studies with mouse-adapted SARS-CoV-2 virus) coupled with the ability to manipulate unconventional T cell numbers and activity (e.g., CD1d KO, MR1 KO, and TCRδ KO mice). In this issue of JEM, Jouan et al. (https://doi.org/10.1084/jem.20200872) report the activation and skewed function of unconventional T cells in severe COVID-19 patients.
    keywords: cells; covid-19
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        item: #4982 of 7819
          id: cord-318437-tzp33iw7
      author: Lovrić, Mario
       title: Understanding the true effects of the COVID-19 lockdown on air pollution by means of machine learning()
        date: 2020-11-06
       words: 2852
      flesch: 46
     summary: 192 The machine learning algorithm used was Random Forest regression (RF) (Breiman, 193 2001) which has been utilized in a number of previous air pollution models and air quality data shown in Figure 4 . [WWW Document Anteil der verkehrsbedingten PM10 und PM2,5 Emissionen aus Abrieb 541 und Wiederaufwirbelung an der Feinstaubbelastung in Österreich Assessing air quality changes in large cities during COVID-19 lockdowns: 545
    keywords: air; covid-19; data; lockdown; pollution
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        item: #4983 of 7819
          id: cord-318457-k5kkd5qp
      author: Yoganathan, Anusha
       title: Cardiovascular disease and the impact of COVID‐19
        date: 2020-06-16
       words: 252
      flesch: 17
     summary: 2, 4 The study by Zhang et al 4 At the heart of COVID-19 Reninangiotensin-aldosterone system blockers and the risk of Covid-19 Continuing versus suspending angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: impact on adverse outcomes in hospitalized patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Association of inpatient use of angiotensin converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19 One of the most important pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is lying in its affinity to renin-angiotensin-aldosterone system (RAAS) through angiotensin converting enzyme inhibitor (ACEi) or utilization of angiotensin receptor blockers (ARBs).
    keywords: angiotensin
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        item: #4984 of 7819
          id: cord-318458-jadk2qbm
      author: Jung, Chan-Young
       title: Association between Body Mass Index and Risk of COVID-19: A Nationwide Case-Control Study in South Korea
        date: 2020-08-25
       words: 3660
      flesch: 43
     summary: In multivariable logistic regression models adjusted for sociodemographic, comorbidity, laboratory and medication data, there was a graded association between higher BMI levels and higher risk of COVID-19 infection; compared to normal weight individuals, the adjusted ORs in the overweight and obese individuals were 1.13 (95% CI, 1.03-1.25) and 1.26 (95% CI, 1.15-1.39), respectively. In logistic regression models that were adjusted for socio-demographic, comorbidity, laboratory and medication data, there was a graded association between higher BMI levels and higher risk of COVID-19 infection (Figure 1 ).
    keywords: bmi; covid-19; obesity; patients; risk; study
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        item: #4985 of 7819
          id: cord-318470-2plv75os
      author: Russell, Matthew R.
       title: COVID-19 in a pediatric heart transplant recipient: Emergence of Donor Specific Antibodies
        date: 2020-04-29
       words: 532
      flesch: 39
     summary: We would be hesitant to attempt more aggressive forms of desensitization with active infection until more clinical knowledge of COVID-19 infection is available. This patient tolerated IVIG administration with concurrent COVID-19 infection without any notable reaction.
    keywords: covid-19; transplant
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        item: #4986 of 7819
          id: cord-318483-il5aq8py
      author: Perez Gaxiola, G.
       title: Clinical and epidemiological characteristics of children with SARS-CoV-2 infection: case series in Sinaloa
        date: 2020-07-11
       words: 1761
      flesch: 45
     summary: Coronavirus Disease 2019 in Children United States Screening and Severity of Coronavirus Disease 2019 (COVID-19) in Children in Madrid Coinfection and Other Clinical Characteristics of COVID-19 in Children Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents: A Systematic Review Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults COVID-19) in children and/or adolescents: a metaanalysis Children's mortality from COVID-19 compared with all-deaths and other relevant causes of death: epidemiological information for decision-making by parents, teachers, clinicians and policymakers. Clinical management of COVID-19 Chest computed tomography in children with COVID-19 respiratory infection Clinical and CT imaging features of the COVID-19 pneumonia:
    keywords: children; covid-19; disease; patients; sars
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        item: #4987 of 7819
          id: cord-318484-b21myin4
      author: Di Lorenzo, G.
       title: Evaluating the adequacy of Prima Covid-19 IgG/IgM Rapid Test for the assessment of exposure to SARS-CoV-2 virus
        date: 2020-06-03
       words: 1664
      flesch: 43
     summary: The Covid-19 IgG/IgM Rapid test represents a low-cost and easily applicable tool in detecting SARS-Cov-2 diffusion in the general population with the capability to identify quite reliably subjects who have been or have not been exposed to the virus in the recent or distant past, as suggested by the presence or absence of specific IgG. Our data suggest that the test is unlikely to provide adequate information regarding the most recent or current exposure to the virus given the evident unreliability of IgM antibodies detection, which must be conformed by a RT-PCR test. Given the difficulty in securing an adequate supply of RT-PCR kits, we at the Centro Medico Santagostino decided to test a qualitative serological test, the Prima Lab SA Covid-19 IgG/IgM Rapid test, to assess the efficacy and the weaknesses of rapid tests.
    keywords: igg; igm; rapid; test
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        item: #4988 of 7819
          id: cord-318492-uu1p1rgi
      author: Mansueto, Gelsomina
       title: COVID-19: Brief Check Point Through The Pathologist's Eye (autopsy archive)
        date: 2020-08-28
       words: 1973
      flesch: 29
     summary: The test is primarily used to detect SARS-CoV-2 and to distinguish it from other viral agents responsible for similar types of pneumonia. This shows that although Sars-CoV-2 has high virulence, it behaves like other viruses, that in the population the symptoms occur in subjects often with comorbidities and that deaths are due to complications in the same way as it happens for other viral agents.
    keywords: autopsy; coronavirus; cov-2; covid-19; damage; sars
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        item: #4989 of 7819
          id: cord-318512-5wvnw8li
      author: Coronado, Pluvio J.
       title: Health-related quality of life and resilience in peri- and postmenopausal women during Covid-19 confinement
        date: 2020-09-28
       words: 3628
      flesch: 44
     summary: Conclusions During the period of mandatory Covid-19 confinement, peri- and postmenopausal women who engaged in physical and sexual activity had higher HRQoL and higher levels of resilience, whilst women who were using antidepressants had lower HRQoL and lower levels of resilience. key: cord-318512-5wvnw8li authors: Coronado, Pluvio J.; Fasero, Maria; Otero, Borja; Sanchez, Sonia; Viuda, Esther de la; Ramirez-Polo, Isabel; Llaneza, Placido; Mendoza, Nicolas; Baquedano, Laura title: Health-related quality of life and resilience in peri- and postmenopausal women during Covid-19 confinement date: 2020-09-28 journal: Maturitas DOI: 10.1016/j.maturitas.2020.09.004 sha: doc_id: 318512 cord_uid: 5wvnw8li Objective To assess the impact of confinement due to the coronavirus (Covid-19) pandemic on health-related quality of life (HRQoL) and resilience in peri- and postmenopausal women.
    keywords: cervantes; covid-19; hrqol; postmenopausal; resilience; women
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        item: #4990 of 7819
          id: cord-318520-hgjv7ot9
      author: Mohamed, Sherif
       title: Death due to Cardiac Arrest in a Young Female With Highly Suspected COVID-19: A Case Report
        date: 2020-08-30
       words: 1949
      flesch: 41
     summary: As COVID-19 patients are commonly having clotting disorders, endothelial and organ dysfunction, coagulopathy, and liable for pulmonary thromboembolism (PTE), it is important to select those COVID-19 patients who are at higher risk of PTE, and practice CT pulmonary angiography (CTPA) for the diagnosis of PTE, especially in case of significant increase of D-dimer values. Acute pulmonary embolism (PE), reported in COVID-19 patients, has been shown to be a cause of clinical deterioration in viral types of pneumonia, as well [7] .
    keywords: case; covid-19; disease; patients; pulmonary
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        item: #4991 of 7819
          id: cord-318542-785hnh19
      author: Leeson, Cale E.
       title: Systematic Review: Safety of Intravesical Therapy for Bladder Cancer in the Era of COVID-19
        date: 2020-08-18
       words: 2672
      flesch: 34
     summary: [9] Intravesical BCG treatment in immunocompromised patients remains a relative contraindication in some guidelines 7 , while its role in the treatment of acute immunological disorders remains uncertain. We aim to review and summarize what is known about COVID-19 and the current implications of intravesical BCG with regard to the disease.
    keywords: bcg; bladder; cancer; covid-19; disease; patients
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        item: #4992 of 7819
          id: cord-318592-08mjfs83
      author: Chen, L.
       title: Clinical Characteristics of Recurrent-positive Coronavirus Disease 2019 after Curative Discharge: a retrospective analysis of 15 cases in Wuhan China
        date: 2020-07-04
       words: 3113
      flesch: 48
     summary: It has been found that during the post-discharge isolation and observation period, a few patients again show positive results on RT-PCR tests. Recurrent-positive COVID-19 was defined as positive results on RT-PCR testing of a nasopharyngeal swab collected during the post-discharge isolation and observation period.
    keywords: covid-19; group; medrxiv; patients; pcr; preprint
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        item: #4993 of 7819
          id: cord-318599-drvjr7gq
      author: Amankwah-Amoah, Joseph
       title: Note: Mayday, Mayday, Mayday! Responding to environmental shocks: Insights on global airlines’ responses to COVID-19
        date: 2020-09-29
       words: 5026
      flesch: 36
     summary: A network model of effects of social distancing on airline business model. The airliner once dubbed the Queen of the Skies, the most recognisable among the public as well as the preferred choice of global airlines for long-haul routes (Flight International, 2020; Specia, 2020) .
    keywords: airlines; coronavirus; covid-19; crisis; distancing; firms; flight; industry; responses; term
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        item: #4994 of 7819
          id: cord-318634-crjg72fj
      author: Weiss, Pnina G.
       title: Leading Change to Address the Needs and Well-being of Trainees During the COVID-19 Pandemic
        date: 2020-06-05
       words: 2349
      flesch: 36
     summary: In this paper, we adapt Maslow's needs framework to systematically address trainee well-being during the COVID-19 pandemic and identify potential interventions to meet trainee needs at the program, institution, and extra-institutional levels. 5 Food service closures, physical distancing and infection control measures, time constraints, and expense may limit trainee access to food.
    keywords: covid-19; education; needs; pandemic; program; trainees
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        item: #4995 of 7819
          id: cord-318655-i9kv7bph
      author: Lu, Zhenzhen
       title: A fractional-order SEIHDR model for COVID-19 with inter-city networked coupling effects
        date: 2020-08-05
       words: 3950
      flesch: 51
     summary: A large number of articles have discussed the stability of fractional order systems in different ways [15] [16] Khan et al. described the interaction between bats and unknown hosts, people to people, and the source of infection (seafood market), and their work shown fractional model played an important role in limiting the number of infected people [21] .
    keywords: covid-19; model; order; system
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        item: #4996 of 7819
          id: cord-318675-lrrro5g9
      author: KARIMI, S. M.
       title: Spring Weather and COVID-19 Deaths in the U.S.
        date: 2020-06-22
       words: 9950
      flesch: 53
     summary: County-level daily death rates in the left-hand-side (dependent variable) of all statistical models were weighted by county population 18 years and older. When the average minimum temperature within a five-day window increased by one degree Fahrenheit in spring 2020, daily death rates in northern U.S. counties increased by an estimated 5.1%.
    keywords: average; county; covid-19; day; deaths; level; license; medrxiv; ozone; preprint; temperature; weather
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        item: #4997 of 7819
          id: cord-318681-enq0j6dr
      author: Kim, Je Hyeong
       title: Experience of augmenting critical care capacity in Daegu during COVID-19 incident in South Korea
        date: 2020-05-31
       words: 2707
      flesch: 38
     summary: Global Care has provided funds for the introduction of essential equipment in cooperation with the Daegu Community Chest of Korea, while contacting various medical-related organizations to recruit intensive care medical personnel. For medical personnel to properly treat critically ill patients in expanded beds, essential equipment for the treatment of critical patients must be secured.
    keywords: beds; care; daegu; hospital; patients
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        item: #4998 of 7819
          id: cord-318694-370ccaoc
      author: Khanna, Niharika
       title: Utilizing the Learning Health System Adaptation to guide Family Medicine Practice to COVID-19 response
        date: 2020-10-16
       words: 1613
      flesch: 39
     summary: Scheduled televisits with COVID-19 positive patients helped allay anxiety, encouraged chronic disease care, tobacco cessation, and medication adherence. There was a pressing need for innovation in order to meet the needs of the population that needed outreach, COVID-19 care and preventive services.
    keywords: care; covid-19; health; pandemic; patients; staff
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        item: #4999 of 7819
          id: cord-318697-6o0i4gir
      author: Armitage, Richard
       title: Whistleblowing and patient safety during COVID-19
        date: 2020-06-24
       words: 548
      flesch: 30
     summary: key: cord-318697-6o0i4gir authors: Armitage, Richard; Nellums, Laura B title: Whistleblowing and patient safety during COVID-19 date: 2020-06-24 journal: EClinicalMedicine DOI: 10.1016/j.eclinm.2020.100425 sha: doc_id: 318697 cord_uid: 6o0i4gir nan It has been rightly noted that health workers globally must be able to speak out during COVID-19, allowing them to draw public attention to inadequate PPE supplies and unsafe working conditions, while being protected from censorship, attack, government intimidation, harassment, and arrest [1] . But such systemic failure to provide health workers with the resources they need represents only one of numerous situations in which clinicians may consider raising the alarm.
    keywords: health; patient
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        item: #5000 of 7819
          id: cord-318701-f9j13fsc
      author: Chamboredon, P.
       title: COVID‐19 pandemic in France: health emergency experiences from the field
        date: 2020-06-22
       words: 4676
      flesch: 44
     summary: We have also drawn on our experiences as French nurses. The most reliable indicator to date remains the incidence of COVID-19 cases entering resuscitation/critical care every day, which is beginning to plateau.
    keywords: care; covid-19; crisis; france; government; health; measures; nurses; nursing; population
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        item: #5001 of 7819
          id: cord-318737-b32tk5ze
      author: Stickley, Andrew
       title: COVID-19 preventive behaviours among people with anxiety and depressive symptoms: Findings from Japan
        date: 2020-10-10
       words: 1606
      flesch: 44
     summary: Although a study from China reported that neither state nor trait anxiety was associated with COVID-19 preventive behaviours, 5 other recent studies have all linked anxiety with an increased likelihood of engaging in preventive behaviours. A brief measure for assessing generalized anxiety disorder: the GAD-7 Public perceptions and preventive behaviours during the early phase of the COVID-19 pandemic: a comparative study between Assessment of community psycho-behavioral responses during the outbreak of novel coronavirus (2019-nCoV): a cross sectional study Anxiety and depressive symptoms were the exposures; COVID-19 preventive behaviours were the outcomes Coef: coefficient; CI: confidence interval Both analyses were adjusted for age (ref. young), sex (ref. female), education (ref.
    keywords: anxiety; behaviours; covid-19; study
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        item: #5002 of 7819
          id: cord-318755-fip8wj6y
      author: El Kassas, Mohamed
       title: Liver transplantation in the era of COVID-19
        date: 2020-05-12
       words: 4272
      flesch: 34
     summary: Although healthcare facilities are overwhelmed with management of COVID-19 patients & health resources are being rapidly consumed, the American Association for the Study of Liver Diseases (AASLD), recommended against postponing transplantation. Immunosuppressive therapy should be started in patients with liver disease with or without COVID-19 who have strong indications for treatment (e.g., autoimmune hepatitis, liver transplant patients, and in cases of graft rejection).
    keywords: care; covid-19; disease; infection; liver; ltx; patients; recipients; risk; transplant; transplantation
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        item: #5003 of 7819
          id: cord-318756-yln4htof
      author: Naderi, Nasim
       title: Cardiovascular patients in COVID‐19 era, a case series, an experience from a tertiary cardiovascular center in Tehran, Iran
        date: 2020-07-23
       words: 3041
      flesch: 47
     summary: retrospective study Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical features and treatment of COVID-19 patients in northeast Chongqing Coronavirus Disease 2019 in elderly patients: characteristics and prognostic factors based on 4-week follow-up Does the novel coronavirus 2019 like heart more than the other family members of coronaviruses? Regardless of many clinicians' concerns about susceptibility to coronavirus in those patients who are taking ACEIs or ARBS, observational studies have not provided convincing data on whether these drugs have potentially beneficial or harmful effects on COVID-19 patients.
    keywords: cardiovascular; case; coronavirus; covid-19; disease; figure; patients
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        item: #5004 of 7819
          id: cord-318757-po0zpvw5
      author: Beig, Gufran
       title: COVID-19 and Environmental -Weather Markers: Unfolding Baseline Levels and Veracity of Linkages in Tropical India
        date: 2020-08-22
       words: 2005
      flesch: 51
     summary: Present work tends to suggest a 336 significant rise in the fatality in people with underlying conditions because of chronic 337 exposure to baseline air pollution levels rather than averaged ambient air pollution levels for 338 PM 2.5 and shown in Figure 1 To understand the association of COVID-19 with weather and climatological parameters, the 360 correlation study has been done in the present work. Although there are numerous confounding factors for the pandemic, we find a strong association of COVID-19 mortality with baseline PM(2.5) levels (80% correlation) to which the population is chronically exposed and may be considered as one of the critical factors.
    keywords: baseline; correlation; covid-19; levels
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        item: #5005 of 7819
          id: cord-318773-nmsr1ga1
      author: Blanco-Colino, Ruth
       title: Authors’ response to: About the scientific letter «Suspicion of an acute abdomen as an extrapulmonary manifestation of COVID-19 infectio»
        date: 2020-07-17
       words: 610
      flesch: 34
     summary: This could also be the case of inadequate protection against patients presenting in the emergency department with gastrointestinal symptoms associated with COVID-19 and mild or no pulmonary symptoms; some 10% present chest radiographs without pneumonia, as in the case reported. In addition, another reason for the need to identify early suspicion is to avoid dissemination among other patients who come to the Surgical Emergency Unit for other reasons and to avoid infection of healthcare workers, who are the gateway to the healthcare system and who are often unprotected.
    keywords: covid-19; symptoms
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        item: #5006 of 7819
          id: cord-318808-1cfwj5uq
      author: Li, Ying
       title: Comparison of Hospitalized Patients with pneumonia caused by COVID-19 and influenza A in children under 5 years
        date: 2020-06-12
       words: 1656
      flesch: 45
     summary: Two group of COVID-19 patients (n=57) and influenza A patients (n=59) were enrolled. Results The proportions of cough (70.2%), fever (54.4%) and gastrointestinal symptoms (14.1%) in COVID-19 patients were lower than those of influenza A patients (98.3%, P<0.001; 84.7%, P<0.001; and 35.6%, P=0.007; respectively).
    keywords: children; covid-19; influenza; patients
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        item: #5007 of 7819
          id: cord-318817-95tw84z8
      author: Hubner, C. v. K.
       title: Distress among Brazilian university students due to the Covid-19 pandemic: survey results and reflections
        date: 2020-06-20
       words: 2074
      flesch: 51
     summary: The women who responded showed higher psychological distress when compared to men (mean (SD) = 47.14 Age did not appear to be a significant predictor of psychological distress (p=0.738), as occurred in a Chinese study sample. The study provides the first empirical evidence on the level of psychological distress in Brazilian university students during the Covid-19 pandemic.
    keywords: distress; license; preprint; students
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        item: #5008 of 7819
          id: cord-318821-m8vx0wgs
      author: Jombart, T.
       title: Real-time monitoring of COVID-19 dynamics using automated trend fitting and anomaly detection
        date: 2020-09-03
       words: 6952
      flesch: 44
     summary: The general framework used in ASMODEE could in theory be extended to multivariate time series models incorporating spatial dependency, but the current implementation would need additional work to support such features. Considered temporal trends models included: Poisson GLM with constant mean, linear regression with linear trend in time, negative binomial GLM with log-linear trend in time, the same with a 'day of the week' effect (distinguishing weekends, Mondays, and other days), and the latter with an additional interaction to allow for different slopes by day of the week.
    keywords: asmodee; covid-19; data; days; detection; model; points; preprint; series; time; trend
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        item: #5009 of 7819
          id: cord-318831-hocenr09
      author: Ahluwalia, Amrit S.
       title: Bilateral Pneumothoraces as Possible Atypical Presentation of Coronavirus Disease 2019 (COVID-19)
        date: 2020-09-11
       words: 1324
      flesch: 39
     summary: Therefore, we suspect that the findings of pneumomediastinum, bilateral pneumothorax, and subcutaneous emphysema are related to COVID-19. Individuals with as few as three days of symptoms may present with pneumomediastinum, bilateral pneumothorax, and subcutaneous emphysema related to COVID-19.
    keywords: covid-19; pneumomediastinum; pneumothorax
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        item: #5010 of 7819
          id: cord-318858-x8p0n6r3
      author: Hope, Michael D
       title: A role for CT in COVID-19? What data really tell us so far
        date: 2020-03-27
       words: 1398
      flesch: 53
     summary: They found that 97% of cases with RT-PCR-confirmed diagnoses had CT findings of pneumonia, and conclude, CT imaging has high sensitivity for diagnosis of COVID-19. We urge caution and encourage using published guidelines 3 regarding use of CT imaging.
    keywords: covid-19; health; pandemic; patients
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        item: #5011 of 7819
          id: cord-318866-3arxrm8m
      author: Magnano, M.
       title: Psoriasis, COVID‐19 and acute respiratory distress syndrome: focusing on the risk of concomitant biological treatment
        date: 2020-05-30
       words: 694
      flesch: 45
     summary: Our case series roughly reflects the study of Gisondi et al. 1 , who concluded that, despite the cardiovascular and metabolic comorbidities affecting psoriatic patients and also representing risk factors for severe COVID-19, patients seldom required hospitalization. key: cord-318866-3arxrm8m authors: Magnano, M.; Balestri, R.; Bardazzi, F.; Mazzatenta, C.; Girardelli, C.R.; Rech, G. title: Psoriasis, COVID‐19 and acute respiratory distress syndrome: focusing on the risk of concomitant biological treatment date: 2020-05-30 journal: Dermatol Ther DOI: 10.1111/dth.13706 sha: doc_id: 318866 cord_uid: 3arxrm8m nan The management of psoriatic patients under biologics during SARS-CoV-2 outbreak is of great concern, as well as the outcome of the COronaVirus DIsease (COVID-19) in this population.
    keywords: covid-19; patients
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        item: #5012 of 7819
          id: cord-318871-ffyavhm0
      author: Sy, K. T. L.
       title: Previous and active tuberculosis in COVID-19 patients increases risk of death and prolongs recovery
        date: 2020-07-26
       words: 2517
      flesch: 49
     summary: COVID-19 has and will continue to cause substantial strain to healthcare systems worldwide, and predictions expect increased mortality among TB patients due to significant TB program disruptions, diagnostic delays, TB treatment interruptions, and lack of access to drugs (6, 7, 9) . In particular, there has been decreases in care seeking for TB treatment, lessened enrollment in TB research studies, interruptions in availability of TB medicine and other products, and issues with obtaining food and nutritional support during the pandemic (9).
    keywords: covid-19; license; patients; preprint; time
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        item: #5013 of 7819
          id: cord-318879-4ual2ssa
      author: Kaveh-Yazdy, Fatemeh
       title: Track Iran's National COVID-19 Response Committee’s Major Concerns using Two-stage Unsupervised Topic Modeling
        date: 2020-11-04
       words: 6261
      flesch: 53
     summary: chat Twitter sentiment classification for measuring public health concerns Monitoring public health concerns using twitter sentiment classifications Understanding the perception of COVID-19 policies by mining a multilanguage Twitter dataset Unpacking the black box: How to promote citizen engagement through government social media during the COVID-19 crisis Health Communication Through News Media During the Early Stage of the COVID-19 Outbreak in China: There is a limited number of expressed concerns and set up actions enlisted by Abdi [70] .
    keywords: concerns; covid-19; disease; et al; information; model; ncrc; news; number; outbreak; sentences; topic
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        item: #5014 of 7819
          id: cord-318892-1vyhsg5k
      author: AbdAllah, Mohamed
       title: Role of micronutrients in the management of COVID-19
        date: 2020-10-10
       words: 635
      flesch: 40
     summary: Pathogens A Comprehensive Literature Review on the Clinical Presentation, and Management of the Pandemic Coronavirus Disease 2019 (COVID-19) SARS-CoV-2: a storm is raging Micronutrient status of COVID-19 patients: a critical consideration Nutritional recommendations for CoVID-19 quarantine Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture Nutritional status and COVID-19: an opportunity for lasting change key: cord-318892-1vyhsg5k authors: AbdAllah, Mohamed; Elarab, Hanan Ez; Raslan, Eman; Saber, Lobna; Daoud, Eitedal; Saber, Maha title: Role of micronutrients in the management of COVID-19 date: 2020-10-10 journal: New Microbes New Infect DOI: 10.1016/j.nmni.2020.100782 sha: doc_id: 318892 cord_uid: 1vyhsg5k Micronutrients play an important role in enhancing the immune system, therefore, proper nutritional support of micronutrients could have a positive impact on COVID-19 outcome. virus.
    keywords: covid-19; micronutrients; outcome
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        item: #5015 of 7819
          id: cord-318893-obcdapgb
      author: Cheng, Shao-Chung
       title: Author reply to Letters to the Editor “COVID-19 pneumonia in Taiwan”
        date: 2020-04-02
       words: 295
      flesch: 48
     summary: Joob B. et al. highlighted that COVID-19 cases might still had undetected viral shedding and still were infectious. key: cord-318893-obcdapgb authors: Cheng, Shao-Chung; Fan Chiang, Yu-Long; Huang, Chia-Husn; Hsu, Yuan-Nian title: Author reply to Letters to the Editor “COVID-19 pneumonia in Taiwan” date: 2020-04-02 journal: J Formos Med Assoc DOI: 10.1016/j.jfma.2020.03.011 sha: doc_id: 318893 cord_uid: obcdapgb nan Author reply to Letters to the Editor COVID-19 pneumonia in Taiwan We would like to thank Joob B. et al. for showing their interest in our article First case of Coronavirus Disease 2019 (COVID-19) pneumonia in Taiwan 1 and sharing their idea selflessly on our work.
    keywords: covid-19
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        item: #5016 of 7819
          id: cord-318906-p7wb6kjd
      author: Changzheng, He
       title: How should colorectal surgeons practice during the COVID‐19 epidemic? A retrospective single‐center analysis based on real‐world data from China
        date: 2020-05-28
       words: 2044
      flesch: 49
     summary: Flowchart of diagnosis and treatment for colorectal cancer patients during COVID-19 is shown in Figure 1 . Chinese expert consensus on surgical diagnosis and treatment strategies for colorectal cancer patients during corona virus disease An interactive web-based dashboard to track COVID-19 in real time Global cancer statistics 2018:
    keywords: cancer; covid-19; patients; surgery; treatment
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        item: #5017 of 7819
          id: cord-318909-h5b7mncf
      author: Liguori, Claudio
       title: Subjective neurological symptoms frequently occur in patients with SARS-CoV2 infection
        date: 2020-05-19
       words: 3480
      flesch: 38
     summary: Although the involvement of nervous system during SARS-CoV2 infection has been extensively proposed, [10] [11] [12] few studies focused the investigation on neurological symptoms in patients with 7 The largest study examining the neurological manifestations of hospitalized patients with COVID-19 was a retrospective analysis achieved by reviewing patients' clinical charts. A part the respiratory illness, an increasing number of reports pointed out that SARS-CoV2 can also affect the nervous system, since neurological manifestations may occur quite frequently in hospitalized patients.
    keywords: cov2; covid-19; hospitalization; infection; patients; sars; sns
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        item: #5018 of 7819
          id: cord-318916-5lzun9bv
      author: Bruining, Hilgo
       title: COVID-19 and child and adolescent psychiatry: an unexpected blessing for part of our population?
        date: 2020-07-04
       words: 1128
      flesch: 36
     summary: For the field of child and adolescent psychiatry, and child development in general, these may be also related to learning how our social and economic environment interacts with child mental health and well-being. The COVID-19 outbreak has brought new challenges for child psychiatry and mental health services that must be addressed, including national guidelines covering interventions for major public health crises affecting children [8] .
    keywords: adolescent; children; covid-19; health
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        item: #5019 of 7819
          id: cord-318929-hygcbcp0
      author: López-Martin, Inmaculada
       title: Relación entre la gravedad del Covid-19 y el estado vacunal. Resultados de una encuesta anónima entre médicos de atención primaria
        date: 2020-11-07
       words: 938
      flesch: 48
     summary: La encuesta incluyó preguntas sobre demografía, el estado de vacunación (triple vírica, BCG y de la hepatitis B como control), el tipo de exposición, el método de diagnóstico empleado en los contagiados y la gravedad de la infección por SARS-CoV-2. Diferentes hipótesis han especulado sobre el efecto protector frente al Covid-19 que ejerce una inmunidad entrenada por diferentes vacunas, entre las que se incluyen la vacunación con el Bacilo de Calmette-Guerin (BCG) 1 , con las vacunas de la hepatitis A, la polio y con la triple vírica ( sarampión, parotiditis y rubéola) 2 .
    keywords: con; covid-19; del; los; que
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        item: #5020 of 7819
          id: cord-318933-09ym98hx
      author: Betsch, Cornelia
       title: Monitoring behavioural insights related to COVID-19
        date: 2020-04-02
       words: 1548
      flesch: 36
     summary: Although we have already acknowledged the need to balance these two considerations in order to maintain public understanding and trust, we do not accept that conflict is inevitable as our approach requires all Vaccination and trusthow concerns arise and the role of communication in mitigating crises Risk communication for public health emergencies Communicating risk in public health emergencies: a WHO guideline for emergency risk communication (ERC) policy and practice Risk perception and self-protective behavior Pandemic public health paradox: time series analysis of the 2009/10 Influenza A/H1N1 epidemiology, media attention, risk perception and public reactions in 5 European countries Public perceptions, anxiety, and behaviour change in relation to the swine flu outbreak: cross sectional telephone survey Crisis and emergency risk communication as an integrative model COVID-19 Snapshot MOnitoring (COSMO): monitoring knowledge, risk perceptions, preventive behaviours, and public trust in the current coronavirus outbreak AZ is co-principal investigator of the Pan-African Network on Emerging and Re-Emerging Infections and is in receipt of a UK National Institutes of Health Research Senior Investigator Award. Preventing global spread of infectious diseases from mass gathering events and protecting global health security require public health decisions based on evidence and an agreed rational framework for decision making.
    keywords: covid-19; health; public; response; risk
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        item: #5021 of 7819
          id: cord-318938-7d731q65
      author: Wallentin, Lars
       title: Angiotensin-converting enzyme 2 (ACE2) levels in relation to risk factors for COVID-19 in two large cohorts of patients with atrial fibrillation
        date: 2020-09-27
       words: 4634
      flesch: 35
     summary: Male sex and clinical or biomarker indicators of biological ageing, cardiovascular disease, and diabetes are associated with higher sACE2 levels. In unadjusted analyses and after adjustment for clinical variables and medical treatment, male sex, diabetes, congestive heart failure, prior myocardial infarction, and age were consistently associated with higher sACE2 levels in both cohorts ( Figure 3A ; Supplementary material online, Table S2 ).
    keywords: angiotensin; biomarkers; covid-19; diabetes; disease; level; patients; risk; sace2; sars
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        item: #5022 of 7819
          id: cord-318944-13zk6cco
      author: Bizzoca, Maria Eleonora
       title: Covid-19 Pandemic: What Changes for Dentists and Oral Medicine Experts? A Narrative Review and Novel Approaches to Infection Containment
        date: 2020-05-27
       words: 11704
      flesch: 45
     summary: 7. Before dental session patient should rinse and gargle with a specific mouthwash. The first problem raised with respect to COVID-19, is related to the easy spread of viral agents in the air during dental procedures [12]
    keywords: agents; air; blood; care; contact; control; covid-19; droplets; gloves; hand; health; human; infection; order; patient; procedures; protection; respiratory; risk; surfaces; transmission; use; virus; water
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        item: #5023 of 7819
          id: cord-318965-0mxv8h06
      author: Mastnak, Wolfgang
       title: Psychopathological problems related to the COVID‐19 pandemic and possible prevention with music therapy
        date: 2020-06-01
       words: 1491
      flesch: 36
     summary: Comparative analyses and considerations based on inferential reasoning suggest that this pandemic will involve four substantially different phases with regard to child mental health. Acta Paediatr DOI: 10.1111/apa.15346 sha: doc_id: 318965 cord_uid: 0mxv8h06 COVID-19 is having a profound effect on societies worldwide and the impact that it is having on children cannot be underestimated.
    keywords: children; covid-19; health; music
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        item: #5024 of 7819
          id: cord-318970-aiqggh6h
      author: Sánchez-Raya, Judith
       title: Spinal cord injury and COVID-19: some thoughts after the first wave
        date: 2020-07-21
       words: 1896
      flesch: 41
     summary: The adopted contingency plan had urgent care for acute SCI and for serious complications in patients with chronic SCI as its main goal. This phenomenon could be attributed to the reduced mobility of the population and consequently the risk of accidental trauma in the case of acute SCI and to a reluctance to consult in the case of people with chronic SCI as well.
    keywords: care; covid-19; patients; people; sci
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        item: #5025 of 7819
          id: cord-318976-ptutkd6o
      author: Gul, Fahad
       title: Meta-analysis of outcomes of patients with COVID-19 infection with versus without gastrointestinal symptoms
        date: 2020-05-29
       words: 1552
      flesch: 44
     summary: Comparing patients positive for SARS-COV-2 with concurrent GI symptoms with those without GI symptoms, our analysis found no significant difference in mortality between the two groups, but those with GI symptoms had a significant risk for development of ARDS. This systematic review and meta-analysis explored the current associations of GI symptoms to outcomes of mortality and acute respiratory distress syndrome (ARDS) among patients with COVID-19.
    keywords: patients; studies; symptoms
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        item: #5026 of 7819
          id: cord-318979-1t68f5pp
      author: Kihira, Shingo
       title: Fatal cerebral infarct in a child with COVID-19
        date: 2020-07-23
       words: 338
      flesch: 34
     summary: This is an unfortunate case of a healthy 5-year-old boy with COVID-19 infection complicated by cardiogenic shock and hypercoagulable state. Conflicts of interest None COVID-19: consider cytokine storm syndromes and immunosuppression COVID-19 and its implications for thrombosis and anticoagulation Hypercoagulability of COVID-19 patients in intensive care unit.
    keywords: covid-19; infection
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        item: #5027 of 7819
          id: cord-318980-8cclwzob
      author: Dindarloo, Kavoos
       title: Pattern of disinfectants use and their adverse effects on the consumers after COVID-19 outbreak
        date: 2020-09-30
       words: 4527
      flesch: 46
     summary: The use of personal protective equipment (PPE) such as masks and gloves is one of the requirements when uses of surface disinfectants [13, 45] . 4 Correlation between hand washing frequency, hand disinfection frequency, and surface disinfection frequency according to spearmen rank correlation coefficient other substances such as water to make them ready for use.
    keywords: covid-19; disinfectants; disinfection; frequency; hand; health; hypochlorite; participants; people; use
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        item: #5028 of 7819
          id: cord-318983-rmvqf6s9
      author: SCHMIDT, HARALD
       title: Vaccine Rationing and the Urgency of Social Justice in the Covid‐19 Response
        date: 2020-05-28
       words: 2885
      flesch: 51
     summary: 5 Along with other data at the national level indicating that low-income communities and communities of color are at higher risk of serious illness if infected, 6 these disparities bear out that historically and structurally disadvantaged populations incur a far larger share of the morbidity and mortality burden while being far less able to absorb financial and other costs. So They Brave the Subway Association of County-Level Socioeconomic and Political Characteristics with Engagement in Social Distancing for COVID-19 Variation in COVID-19 Hospitalizations and Deaths across New York City Boroughs Most NYC Coronavirus Testing Done in Whitest and Wealthiest ZIP Codes Low-Income and Communities of Color at Higher Risk of Serious Illness if Infected with Coronavirus The Black Plague Interim Updated Planning Guidance on Allocating and Targeting Pandemic Influenza Vaccine during an Influenza Pandemic Fair Allocation of Scarce Medical Resources in the Time of Covid-19 University of Wisconsin School of Medicine Public Health, Department of Medicine University of Wisconsin School of Medicine Public Health, Department of Medicine.
    keywords: covid-19; groups; health; people; percent; vaccine; years
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        item: #5029 of 7819
          id: cord-318994-1xngjndu
      author: Lier, Audun J.
       title: Case Report: Disseminated Strongyloidiasis in a Patient with COVID-19
        date: 2020-08-14
       words: 1971
      flesch: 38
     summary: This report describes the clinical features of a case of disseminated strongyloidiasis infection and polymicrobial bacteremia in an individual who received immunosuppressive treatment for COVID-19. We report a case of a COVID-19 patient who developed disseminated strongyloidiasis following treatment with high-dose corticosteroids and tocilizumab.
    keywords: covid-19; day; negative; strongyloides; strongyloidiasis
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        item: #5030 of 7819
          id: cord-319007-w3pk3ha1
      author: Zingaropoli, Maria Antonella
       title: Major reduction of NKT cells in patients with severe COVID-19 pneumonia
        date: 2020-11-13
       words: 3860
      flesch: 42
     summary: key: cord-319007-w3pk3ha1 authors: Zingaropoli, Maria Antonella; Perri, Valentina; Pasculli, Patrizia; Dezza, Francesco Cogliati; Nijhawan, Parni; Savelloni, Giulia; La Torre, Giuseppe; D'Agostino, Claudia; Mengoni, Fabio; Lichtner, Miriam; Ciardi, Maria Rosa; Mastroianni, Claudio Maria title: Major reduction of NKT cells in patients with severe COVID-19 pneumonia date: 2020-11-13 journal: Clin Immunol DOI: 10.1016/j.clim.2020.108630 sha: doc_id: 319007 cord_uid: w3pk3ha1 Background: NK cells seem to be mainly involved in COVID-19 pneumonia. Using multiparameter flow cytometry, the subset distribution and immunophenotype of NK cells, NKT cells were investigated in peripheral whole blood samples from COVID-19 subjects and HDs.
    keywords: cells; covid-19; nkt; percentage; pneumonia; subjects
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        item: #5031 of 7819
          id: cord-319013-oytqcifa
      author: Focosi, Daniele
       title: Convalescent Plasma Therapy for COVID-19: State of the Art
        date: 2020-08-12
       words: 7487
      flesch: 25
     summary: A proof of concept single arm multicenter interventional trial Improved clinical symptoms and mortality on severe/critical COVID-19 patients utilizing convalescent plasma transfusion Convalescent plasma treatment of severe COVID-19: a matched control study Effect of convalescent plasma therapy on time to clinical improvement in patients with severe and life-threatening COVID-19: a randomized clinical trial Early safety indicators of COVID-19 convalescent plasma in 5,000 patients Safety update: COVID-19 convalescent plasma in 20,000 hospitalized patients COVID-19) patients with convalescent plasma Get rid of the bad first: therapeutic plasma exchange with convalescent plasma for severe COVID-19 The successful use of therapeutic plasma exchange for severe COVID-19 acute respiratory distress syndrome with multiple organ failure Efficacy of therapeutic plasma exchange in severe COVID-19 patients Successful treatment of plasma exchange followed by intravenous immunoglobulin in a critically ill patient with 2019 novel coronavirus infection Potential effect of blood purification therapy in reducing cytokine storm as a late complication of critically ill COVID-19 Global Vaccine Business Unit on the latest on the coronavirus and Takeda Is it time to rethink UK restrictions on blood donation? Hepatitis E virus in blood components: a prevalence and transmission study in southeast England Pork products associated with human infection caused by an emerging phylotype of hepatitis E virus in England and Wales Hepatitis E risks: pigs or blood-that is the question SARS-coronavirus replication in human peripheral monocytes/macrophages Epitopes required for antibody-dependent enhancement of Ebola virus infection Antibodydependent enhancement of Ebola virus infection Influence of Fc␥RIIA and MBL polymorphisms on severe acute respiratory syndrome Immune phenotyping based on neutrophil-tolymphocyte ratio and IgG predicts disease severity and outcome for patients with COVID-19 Viral kinetics and antibody responses in patients with COVID-19 Global profiling of SARS-CoV-2 specific IgG/IgM responses of convalescents using a proteome microarray Neutralizing antibodies responses to SARS-CoV-2 in COVID-19 inpatients and convalescent patients Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications First infection by all four non-severe acute respiratory syndrome human coronaviruses takes place during childhood Pre-existing and de novo humoral immunity to SARS-CoV-2 in humans Antibody-dependent SARS coronavirus infection is mediated by antibodies against spike proteins Anti-SARS-CoV IgG response in relation to disease severity of severe acute respiratory syndrome The potential danger of suboptimal antibody responses in COVID-19 Symptomatic SARS-CoV-2 infections display specific IgG Fc structures Afucosylated immunoglobulin G responses are a hallmark of enveloped virus infections and show an exacerbated phenotype in COVID-19 Autopsy findings and venous thromboembolism in patients with COVID-19: a prospective cohort study Currently available intravenous immunoglobulin (Gamunex © -C and Flebogamma © DIF) contains antibodies reacting against SARS-CoV-2 antigens High-dose intravenous immunoglobulin as a therapeutic option for deteriorating patients with coronavirus disease 2019 ABO blood group and susceptibility to severe acute respiratory syndrome Inhibition of the interaction between the SARS-CoV Spike protein and its cellular receptor by anti-histo-blood group antibodies HIV-1 incorporates ABO histo-blood group antigens that sensitize virions to complementmediated inactivation Harnessing the natural anti-glycan immune response to limit the transmission of enveloped viruses such as SARS-CoV-2 Specific asparagine-linked glycosylation sites are critical for DC-SIGN-and L-SIGN-mediated severe acute respiratory syndrome coronavirus entry Structural, glycosylation and antigenic variation between 2019 novel coronavirus (2019-nCoV) and SARS coronavirus (SARS-CoV) After demonstration that blood group O health care workers were less likely to become infected with SARS-CoV (137), a research group proved that anti-A blood group natural isoagglutinins (which can also be found in CP plasma from blood group O and B donors) inhibit SARS-CoV entry into competent cells (138) .
    keywords: antibodies; antibody; blood; case; convalescent; coronavirus; covid-19; disease; donors; group; patients; plasma; sars; syndrome; therapy; titers; transfusion; treatment
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        item: #5032 of 7819
          id: cord-319022-1twsxzcd
      author: Desai, Antonio
       title: The role of anti-hypertensive treatment, comorbidities and early introduction of LMWH in the setting of COVID-19: A retrospective, observational study in Northern Italy()
        date: 2020-09-25
       words: 2874
      flesch: 34
     summary: JAMA The 2019 coronavirus: Learning curves, lessons, and the weakest link World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects World Health O. when COVID-19 disease is suspected: interim guidance Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2 Antihypertensive treatment with ACEI/ARB of patients with COVID-19 complicated by hypertension Outcomes in Patients with COVID-19 Infection Taking ACEI/ARB Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2 Association of Inpatient Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers with Mortality Among Patients With Hypertension Hospitalized With COVID-19 Inhibitors of the Renin-Angiotensin-Aldosterone System and Covid-19 Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial Indication, Timing, and Surgical Treatment of Spontaneous Intracerebral Hemorrhage: Systematic Review and Proposal of a Management Algorithm Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy Anti-coagulant and anti-platelet therapy in the COVID-19 patient: a best practices quality initiative across a large health system Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy -Thromb Res We would like to thank and dedicate this paper to all the professional A retrospective, observational study in Northern Italy() date: 2020-09-25 journal: Int J Cardiol DOI: 10.1016/j.ijcard.2020.09.062 sha: doc_id: 319022 cord_uid: 1twsxzcd BACKGROUND: There is a great deal of debate about the role of cardiovascular comorbidities and the chronic use of antihypertensive agents (such as ACE-I and ARBs) on mortality on COVID-19 patients.
    keywords: ace; angiotensin; arbs; covid-19; hospital; mortality; patients
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        item: #5033 of 7819
          id: cord-319066-jdvvegp9
      author: Bressan, Silvia
       title: Preparedness and response to Pediatric CoVID-19 in European Emergency Departments: a survey of the REPEM and PERUKI networks
        date: 2020-05-15
       words: 4027
      flesch: 40
     summary: Overall 46% of centers agreed (36%) or strongly agreed (10%) about the statement My hospital was ready and prepared to handle COVID-19 at the time the outbreak started in our country and 54% agreed (39%) or strongly agreed (15%) when the statement was referred to ED pediatric care. Surge capacity for pediatric suspected COVID-19 cases was variable between centers at an ED, admission ward and intensive care level in terms of number of available rooms/beds ( Table 2 ).
    keywords: care; centers; children; countries; covid-19; eds; number; pediatric; survey
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        item: #5034 of 7819
          id: cord-319089-hxpoy4gd
      author: Du, Li
       title: Prevalence of depression during the SARS, MERS, and COVID-19 pandemics: A protocol for overview of systematic reviews
        date: 2020-09-18
       words: 2222
      flesch: 43
     summary: Coronavirus envelope protein: current knowledge An outbreak of coronavirus OC43 respiratory infection in Normandy, France Human (non-severe acute respiratory syndrome) coronavirus infections in hospitalised children in France Koch's postulates fulfilled for SARS virus The aetiology, origins, and diagnosis of severe acute respiratory syndrome COVID-19 and cancer: a comprehensive review Novel Coronavirus(2019-nCoV) Situation Report -33 Challenges and strategies to research ethics in conducting COVID-19 research First case of 2019 novel Coronavirus in the United States Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: a web-based cross-sectional survey Prevalence of stress, anxiety, depression among the general population during the COVID-19 pandemic: a systematic review and meta-analysis Stress, anxiety, and depression levels in the initial stage of the COVID-19 outbreak in a population sample in the northern Spain Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed Reporting of declarations and conflicts of interest in WHO guidelines can be further improved The skills and experience of GRADE methodologists can be assessed with a simple tool The reporting characteristics and methodological quality of Cochrane reviews about health policy research Long-term clinical outcomes in survivors of severe acute respiratory syndrome and Middle East respiratory syndrome coronavirus outbreaks after hospitalisation or ICU admission: a systematic review and meta-analysis The psychological and mental impact of coronavirus disease 2019 (COVID-19) on medical staff and general public: a systematic review and meta-analysis Video calls for reducing social isolation and loneliness in older people: a rapid review Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis Mental health during the COVID-19 outbreak in China: a meta-analysis Psychological intervention on COVID-19: a protocol for systematic review and meta-analysis Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic Impact of coronavirus syndromes on physical and mental health of health care workers: systematic review and meta-analysis Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both Psychological effects caused by the COVID-19 pandemic in health professionals: a systematic review with meta-analysis Psychological status among different populations during COVID-19 epidemic: a systematic review and Metaanalysis The authors thank the assistance of Dr. Jin-Hui Tian Dr., Ke-Lu Yang, and Dr. YA Gao to improve the methodology and quality of language in our manuscript. Increasing systematic reviews (SRs) of coronavirus were focusing on depression.
    keywords: coronavirus; covid-19; depression; meta; review; srs
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        item: #5035 of 7819
          id: cord-319091-hkuc2xqm
      author: Loscocco, Giuseppe G.
       title: Secondary hemophagocytic lymphohistiocytosis, HScore and COVID-19
        date: 2020-05-30
       words: 620
      flesch: 34
     summary: Conversely in a more recent paper [4] , the use of HScore for COVID-19 patients has been questioned. [1] , Prof Takami exposed, competently, the possibility to treat secondary hemophagocytic lymphohistiocytosis (sHLH) in COVID-19 patients with low-dose etoposide.
    keywords: covid-19; hscore
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        item: #5036 of 7819
          id: cord-319113-844o9nr2
      author: AL-Rasheedi, Mabrouk
       title: Public and healthcare providers awareness of Coronavirus (COVID-19) in Qassim Region, Saudi Arabia
        date: 2020-09-10
       words: 3574
      flesch: 48
     summary: The questionnaire was used to gather participants demographics and public participants awareness as well as healthcare providers awareness of the pandemic. Results showed that there were significant differences of awareness levels among different groups of age and sex in response to the identification of COVID-19 treatment.
    keywords: awareness; covid-19; disease; groups; participants; saudi; study
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        item: #5037 of 7819
          id: cord-319140-wxe0tpzs
      author: Yang, Bin
       title: Computed tomography findings in a case of coronavirus disease 2019
        date: 2020-05-12
       words: 1451
      flesch: 42
     summary: Owing to the fast imaging speed and high-intensity resolution, chest CT, especially high-resolution CT, has become the preferred imaging modality for suspected COVID-19 cases or patients who have negative results on nucleic acid tests. However, the imaging findings of COVID-19 lack specificity and CT should mainly be used in differentiating the disease from other viral pneumonias.
    keywords: coronavirus; covid-19; diagnosis; imaging
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        item: #5038 of 7819
          id: cord-319170-idv2cio4
      author: Devita, Maria
       title: The psychological and cognitive impact of Covid-19 on individuals with neurocognitive impairments: research topics and remote intervention proposals
        date: 2020-06-24
       words: 2075
      flesch: 26
     summary: Finally, also the possible motor impairments associated to quarantine should not be underestimated: a forced reduction of motor/physical activity can cause, particularly in older individuals with neurocognitive disorders, a progressive loss of personal and instrumental autonomy, as well as a possible worsening of other agingrelated clinical problems, as sarcopenia, with a consequent increased risk of falls, and subsequent medical geriatrics complications. When Covid-19 quarantine ends, all the remote modalities deployed up till then will be evaluated and carefully considered; if found to be accurate, these new measures will likely constitute alternative, at distance methods that allow social distancing to be maintained; this is particularly important for older individuals.
    keywords: covid-19; disorders; individuals; people; quarantine
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        item: #5039 of 7819
          id: cord-319226-yvgvyif0
      author: French, Jeff
       title: Key Guidelines in Developing a Pre-Emptive COVID-19 Vaccination Uptake Promotion Strategy
        date: 2020-08-13
       words: 6356
      flesch: 36
     summary: Since the beginning of the COVID-19 pandemic there has been a tsunami of misinformation and conspiracy theories that have the potential to reduce vaccine uptake. Since the beginning of the COVID-19 pandemic, we have witnessed a tsunami of misinformation and conspiracy theories that have the potential to reduce vaccine uptake.
    keywords: authorities; covid-19; governments; health; hesitancy; key; media; need; people; public; strategy; uptake; vaccination; vaccine
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        item: #5040 of 7819
          id: cord-319232-qowtuhh6
      author: Brazil, Victoria
       title: Translational simulation for rapid transformation of health services, using the example of the COVID-19 pandemic preparation
        date: 2020-06-03
       words: 3387
      flesch: 33
     summary: However, simulation services and programs that are 'truly translational' [1, 2] -integrated and focused on emerging clinical priorities-are undertaking unprecedented volumes of simulation activity. key: cord-319232-qowtuhh6 authors: Brazil, Victoria; Lowe, Belinda; Ryan, Leanne; Bourke, Rachel; Scott, Clare; Myers, Simone; Kaneko, Hellen; Schweitzer, Jane; Shanahan, Brenton title: Translational simulation for rapid transformation of health services, using the example of the COVID-19 pandemic preparation date: 2020-06-03 journal:
    keywords: care; covid-19; health; healthcare; pandemic; preparation; service; simulation; teams
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        item: #5041 of 7819
          id: cord-319241-div9rzax
      author: Singh, Bhuchitra
       title: Severe Acute Respiratory Syndrome‐Corona Virus‐2 (SARS‐CoV‐2) and its Effect on Gametogenesis and Early Pregnancy
        date: 2020-09-23
       words: 4391
      flesch: 42
     summary: Specifically, it can be suggested that clinicians practicing assisted reproductive technology should be particularly cautious, as SARS CoV-2 infection and systemic effects may impact testicular tissues, ovarian tissue, and granulosa cells and therefore testicular and ovarian function, spermatozoa, oocyte quality, and Since its first identification, more cases of COVID-19 have been counted than that of MERS and SARS combined.
    keywords: ace2; article; coronavirus; cov-2; covid-19; infection; pregnancy; sars; study; women
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        item: #5042 of 7819
          id: cord-319248-ynoxec7k
      author: Matsuyama, Toshifumi
       title: An aberrant STAT pathway is central to COVID-19
        date: 2020-10-09
       words: 10011
      flesch: 39
     summary: In the nucleus, protein inhibitor of activated STAT3 (PIAS3) and PIAS1 can bind activated STAT3 and STAT1 dimers (5, Fig. 3 ), respectively, and block them from binding to DNA, thus inhibiting STAT mediated transcription. Ramana et al. reported that the IFN-II induction of SOCS3 in STAT1-deficient mouse embryonic fibroblasts was derived from activated STAT3 [61] .
    keywords: activation; activity; cells; coronavirus; cov-2; covid-19; disease; expression; factor; fig; ifn; infection; lung; orf6; pai-1; patients; production; protein; sars; signaling; stat3; type
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        item: #5043 of 7819
          id: cord-319256-7pyinx1a
      author: Jin, Xin
       title: The values of coagulation function in COVID-19 patients
        date: 2020-10-29
       words: 2826
      flesch: 43
     summary: key: cord-319256-7pyinx1a authors: Jin, Xin; Duan, Yongwei; Bao, Tengfei; Gu, Junjuan; Chen, Yawen; Li, Yuanyuan; Mao, Shi; Chen, Yongfeng; Xie, Wen title: The values of coagulation function in COVID-19 patients date: 2020-10-29 journal: PLoS One DOI: 10.1371/journal.pone.0241329 sha: doc_id: 319256 cord_uid: 7pyinx1a OBJECTIVE: To investigate the blood coagulation function in COVID-19 patients, and the correlation between coagulopathy and disease severity. We analyzed the coagulation function in COVID-19 patients through the data including thrombin-antithrombin complex (TAT), α2-plasmininhibitor-plasmin Complex (PIC), thrombomodulin (TM), t-PA/PAI-1 Complex (t-PAIC), prothrombin time (PT), international normalized ratio (INR), activated partial thromboplastin time (APTT), fibrinogen (FIB), thrombin time (TT), D-Dimer (DD), and platelet (PLT).
    keywords: coagulation; covid-19; disease; paic; patients
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        item: #5044 of 7819
          id: cord-319268-mqxwwwcd
      author: Raj, Sumit
       title: Letter to the Editor Regarding: “Case Volumes and Perioperative COVID-19 Incidence in Neurosurgical Patients During a Pandemic: Experiences at Two Tertiary Care Centers in Washington, DC”
        date: 2020-11-03
       words: 907
      flesch: 39
     summary: Case volumes and perioperative COVID-19 incidence in neurosurgical patients during a pandemic: experiences at two tertiary care centers in COVID-19 transmission through asymptomatic carriers is a challenge to containment. Although some attempts have been made to address perioperative COVID-19 transmission, its true incidence is not known.
    keywords: covid-19; pandemic; patients
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        item: #5045 of 7819
          id: cord-319269-20sn3yxt
      author: Li, Chunrong
       title: The Prevention and Control Experience of Maternal Health Care from Chengu, China During the COVID-19 Epidemic
        date: 2020-10-19
       words: 2356
      flesch: 40
     summary: Despite the fact that there is no report of COVID-19 infection among pregnant women in Chengdu, World Health Organization has announced the COVID-19 outbreak a global pandemic. [Notice of Novel Coronavirus Infection I Response Measures Issued by the General Office of Sichuan Provincial People's Government Updates on COVID-19 as of 28 WHO Characterizes COVID-19 as a Pandemic Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Second-Trimester Miscarriage in a Pregnant Woman With SARS-CoV-2 Infection What are the risks of COVID-19 infection in pregnant women? National Health Commission of the People's Republic of China.
    keywords: care; chengdu; covid-19; health; women
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        item: #5046 of 7819
          id: cord-319273-ok2p1h9f
      author: Lai, Yu-Ju
       title: Severe acute respiratory syndrome coronavirus-2 and the deduction effect of angiotensin-converting enzyme 2 in pregnancy
        date: 2020-08-17
       words: 2699
      flesch: 45
     summary: 11-30 Severe acute respiratory syndrome (SARS) caused by SARS coronavirus (SARS-CoV) erupted in November 2002 in Guangdong province, China. 10 Pregnant women may be infected with such serious respiratory disease, and we here review a limited cases series of pregnant women with SARS and MERS, which can be helpful for pregnant women who are infected with SARS-CoV-2.
    keywords: angiotensin; coronavirus; cov-2; covid-19; pregnancy; sars; women
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        item: #5047 of 7819
          id: cord-319278-d0rgrmd2
      author: Iavarone, Massimo
       title: Authors’ reply on HIGH RATES OF 30-DAY MORTALITY IN PATIENTS WITH CIRRHOSIS AND COVID-19
        date: 2020-08-07
       words: 636
      flesch: 40
     summary: So far, no studies have been able to enrol significantly larger cohorts of COVID-19 cirrhotics, although data are warranted in order to better characterize the natural history of Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in this setting. key: cord-319278-d0rgrmd2 authors: Iavarone, Massimo; D’Ambrosio, Roberta; Lampertico, Pietro title: Authors’ reply on HIGH RATES OF 30-DAY MORTALITY IN PATIENTS WITH CIRRHOSIS AND COVID-19 date: 2020-08-07 journal: J Hepatol DOI: 10.1016/j.jhep.2020.08.001 sha: doc_id: 319278 cord_uid: d0rgrmd2 nan Both letters pointed out the limited sample size of our study, which however had already been acknowledged as a possible limitation in the discussion session of our paper.
    keywords: mortality; patients
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        item: #5048 of 7819
          id: cord-319312-fmfj8bkp
      author: Jenab, Yaser
       title: Occurrence of acute coronary syndrome, pulmonary thromboembolism, and cerebrovascular event in COVID‐19
        date: 2020-07-22
       words: 1720
      flesch: 44
     summary: Venous thromboembolism seems to remain underdiagnosed in COVID-19 patients. Since COVID-19 patients are prone to thrombotic events, role of empiric therapeutic anticoagulation (intermediate or full dose) for COVID-19 patients has been proposed but not agreed yet.
    keywords: acute; chest; covid-19; patient; pte
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        item: #5049 of 7819
          id: cord-319333-jwbgytwd
      author: Radmard, Sara
       title: Inpatient Neurology Consultations During the Onset of the SARS-CoV-2 New York City Pandemic: A Single Center Case Series
        date: 2020-07-10
       words: 3408
      flesch: 41
     summary: However, we are not able to comment on how these levels compare to COVID-19 patients without neurologic symptoms in our inpatient population, COVID-19 patients in the outpatient setting, nor to healthy controls. Novel coronavirus infection (COVID-19) in humans: a scoping review and meta-analysis Clinical features of patients infected with 2019 novel coronavirus in Wuhan Neurologic alterations due to respiratory virus infections Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study Neurologic features in severe SARS-CoV-2 infection Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Macrothrombosis and stroke in patients with mild Covid-19 infection Large-vessel stroke as a presenting feature of Covid-19 in the young Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan COVID-19: ICU delirium management during SARS-CoV-2 pandemic Pathological findings of COVID-19 associated with acute respiratory distress syndrome Epidemiology of acute symptomatic seizures among adult medical admissions Seizures associated with coronavirus infections Acute ischaemic stroke and infection: recent and emerging concepts Why now?
    keywords: cov-2; covid-19; data; disease; infection; patients; sars; stroke
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        item: #5050 of 7819
          id: cord-319379-qe56u93a
      author: Patil, Vaishali M.
       title: A systematic review on use of aminoquinolines for the therapeutic management of COVID-19: Efficacy, safety and clinical trials
        date: 2020-05-11
       words: 2818
      flesch: 13
     summary: A restricts influenza A virus replication through degradation of the M1 protein Discovery of cyclosporine A and its analogs as broad-spectrum anti-influenza drugs with a high in vitro genetic barrier of drug resistance In vivo effects of cyclosporine on influenza A virus-infected mice Cyclosporin A inhibits the replication of diverse coronaviruses The SARS coronavirus host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors Anticancer kinase inhibitors impair intracellular viral trafficking and exert broad-spectrum antiviral effects Identification and targeting of an interaction between a tyrosine motif within hepatitis C virus core protein and AP2M1 essential for viral assembly AP-2-associated protein kinase 1 and cyclin G associated kinase regulate hepatitis C virus entry and are potential drug targets Genistein interferes with SDF-1 and HIV mediated actin dynamics and inhibits HIV infection of resting CD4 T cells In vitro combination of anti-cytomegalovirus compounds acting through different targets: role of the slope parameter and insights into mechanisms of action Inhibition of herpes simplex virus type 1 infection by silver nanoparticles capped with mercaptoethane sulfonate Inhibition of influenza virus infection by multivalent sialic acid functionalized gold nanoparticles Inhibition of A/Human/Hubei/3/2005 (H3N2) influenza virus infection by silver nanoparticles in vitro and in vivo Inhibitory effects of silver nanoparticles on H1N1 influenza A virus in vitro Silver nanoparticles inhibit hepatitis B virus replication Interaction of silver nanoparticles with HIV-1 Mode of antiviral action of silver nanoparticles against HIV-1 PVP coated silver nanoparticles block the transmission of cell-free and cell-associated HIV-1 in human cervical culture Silver nanoparticles fabricated in hepes buffer exhibit cytoprotective activities toward HIV-1 infected cells Potential application of silver nanoparticles to control the infectivity of rift valley fever virus in vitro and in vivo Fighting arboviral diseases: low toxicity on mammalian cells, dengue growth inhibition (in vitro), and mosquitocidal activity of centroceras clavulatum synthesized silver nanoparticles Green nanoparticles as a novel control tool against dengue virus (DEN-2) and its primary vector aedes aegypti Interaction of silver nanoparticles with Tacaribe virus Effects of mycophenolic acid on human immunodeficiency virus infection in vitro and in vivo Ex vivo modeling of the effects of mycophenolic acid on HIV infection: considerations for antiviral therapy Abacavir and mycophenolic acid an inhibitor of inosine monophosphate dehydrogenase have profound and synergistic anti-HIV activity Mycophenolic acid inhibits hepatitis C virus replication and acts in synergy with cyclosporin A and interferon-alpha Mycophenolic acid augments interferon stimulated gene expression and inhibits hepatitis C virus infection in vitro and in vivo A screen of FDA-approved drugs for inhibitors of zika virus infection Mycophenolic acid inhibits dengue virus infection by preventing replication of viral RNA Inhibition of dengue virus replication by mycophenolic acid and ribavirin Protective activity of tetracycline analogs against the cytopathic effect of the human immunodeficiency viruses in CEM cells Minocycline attenuates HIV infection and reactivation by suppressing cellular activation in human CD4+ T cells Neuroprotective and anti-human immunodeficiency virus activity of minocycline Minocycline inhibits west nile virus replication and apoptosis in human neuronal cells Minocycline suppresses dengue virus replication by down-regulation of macrophage migration inhibitory factor-induced autophagy Drug repurposing of minocycline against dengue virus infection Minocycline neuroprotects, reduces microglial activation, inhibits caspase 3 induction, and viral replication following japanese encephalitis Screening of an FDA-approved compound library identifies four small-molecule inhibitors of middle east respiratory syndrome coronavirus replication in cell culture
    keywords: chloroquine; coronavirus; covid-19; drug; human; hydroxychloroquine; infection; replication; treatment; virus
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        item: #5051 of 7819
          id: cord-319382-97iwwsfg
      author: Sripadma, Dr. P.V.
       title: Postpartum Atypical Posterior Reversible Encephalopathy Syndrome in a COVID-19 patient- An Obstetric Emergency
        date: 2020-09-26
       words: 517
      flesch: 23
     summary: An Obstetric Emergency date: 2020-09-26 journal: J Stroke Cerebrovasc Dis DOI: 10.1016/j.jstrokecerebrovasdis.2020.105357 sha: doc_id: 319382 cord_uid: 97iwwsfg Encephalopathy in COVID-19 has been widely reported with several reports of posterior reversible encephalopathy syndrome (PRES) speculated to be due to an abrupt surge in blood pressure caused by coronavirus disease. Encephalopathy in COVID-19 has been widely reported with several reports of posterior reversible encephalopathy syndrome (PRES) speculated to be due to an abrupt surge in blood pressure caused by coronavirus disease.
    keywords: covid-19; syndrome
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        item: #5052 of 7819
          id: cord-319408-841c0g1c
      author: Salvatore, Christine M
       title: Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study
        date: 2020-07-23
       words: 4643
      flesch: 48
     summary: Unless medically required, neonates were kept in a closed Giraffe isolette in the same room as their mothers, and were held by mothers for feeding after appropriate hand hygiene, breast cleansing, and placement of a surgical mask. Neonates were tested for SARS-CoV-2 by use of real-time PCR on nasopharyngeal swabs taken at 24 h, 5–7 days, and 14 days of life, and were clinically evaluated by telemedicine at 1 month of age.
    keywords: cov-2; covid-19; days; infection; life; mothers; neonates; sars
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        item: #5053 of 7819
          id: cord-319418-ao0df0q7
      author: Chire Saire, J. E.
       title: Study of Coronavirus Impact on Parisian Population from April to June using Twitter and Text Mining Approach
        date: 2020-08-18
       words: 2390
      flesch: 51
     summary: Therefore, measuring what happens after having the pandemic under control is essential, and the economic issue is important to be monitored, since it goes hand in hand with public health policies for the containment of the pandemic [5] , so that our study will help to show changes in issues that concern the French population at this stage. Health Councils of each country promote health policies, close borders and start a partial or total lockdown.
    keywords: coronavirus; covid-19; health; license; pandemic; preprint
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        item: #5054 of 7819
          id: cord-319436-mlitd45q
      author: Brinati, D.
       title: Detection of COVID-19 Infection from Routine Blood Exams with Machine Learning: a Feasibility Study
        date: 2020-04-25
       words: 4607
      flesch: 44
     summary: This study demonstrated the feasibility and clinical soundness of using blood tests analysis and machine learning as an alternative to rRT-PCR for identifying COVID-19 positive patients. Moreover, we want to investigate the interpretability of our models further, by both having more clinicians validate the current Decision Tree, and possibly construct a more accurate one, so that clinicians can use it as a convenient decision aid to interpret blood tests in regard to COVID-19 suspect cases (even off-line).
    keywords: accuracy; blood; cases; covid-19; medrxiv; models; patients; preprint; sensitivity; test
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        item: #5055 of 7819
          id: cord-319486-zf3ytsph
      author: van Hylckama Vlieg, Astrid
       title: FFP2-mondmasker of chirurgisch mondkapje bij COVID-19
        date: 2020-04-11
       words: 1186
      flesch: 55
     summary: Foto: Shutterstock was het relatieve risico op een in het laboratorium bevestigde griepinfectie voor dragers van FFP2-mondmaskers en dragers van chirurgische mondkapjes 1,09 (95%-BI 0,92 tot 1,28). Het relatieve risico op een in het laboratorium bevestigde griepinfectie en op griepachtige aandoeningen was voor dragers van FFP2-mondmaskers ten opzichte van dragers van chirurgische mondkapjes respectievelijk 1,20
    keywords: bij; chirurgische; een; ffp2; het; mondkapjes; van; voor
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        item: #5056 of 7819
          id: cord-319511-gzanhu4w
      author: Silvestris, Erica
       title: Fertility preservation in cancer patients at the time of COVID-19 pandemic
        date: 2020-09-09
       words: 1046
      flesch: 23
     summary: In conclusion, due to lack of information on COVID-19 transmission through gametes and relative components, it appears essential that, in addition to the government policy to extend the serological test for SP immunization to the full Italian population, cancer patients candidate to FP procedures can be mandatorily screened by nasopahryngeal pad and that both seminal plasma and FFs are explored in their proteomic content before cryopreserving the relative gametes in males and females respectively. key: cord-319511-gzanhu4w authors: Silvestris, Erica; Dellino, Miriam; De Palo, Raffaella title: Fertility preservation in cancer patients at the time of COVID-19 pandemic date: 2020-09-09 journal: J Gynecol Obstet Hum Reprod DOI: 10.1016/j.jogoh.2020.101910 sha: doc_id: 319511 cord_uid: gzanhu4w nan Erica Silvestris 1 *, Miriam Dellino 1 , Raffaella De Palo 2 1Gynecologic Oncology Unit, IRCCS Istituto Tumori Giovanni Paolo II Bari, Italy 2Institutional BioBank, Experimental Oncology and Biobank Management Unit, IRCCS Istituto Tumori Giovanni Paolo II, Bari, Italy *Correspondence: Erica Silvestris M.D. Mail: ericasilvestris85@gmail.com
    keywords: cancer; covid-19; patients; virus
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        item: #5057 of 7819
          id: cord-319519-mb9ofh12
      author: Ding, J.
       title: A network-informed analysis of SARS-CoV-2 and hemophagocytic lymphohistiocytosis genes' interactions points to Neutrophil Extracellular Traps as mediators of thrombosis in COVID-19
        date: 2020-07-02
       words: 7253
      flesch: 42
     summary: HLH genes are significantly enriched within the SARS-CoV-2 host protein interactome 106 In the case of the SARS-Cov-2 pandemic, with widespread impact across the world, there 107 is an urgency that requires the adaptation of different strategies to understand COVID-19. After the method was validated, we compared the connectivity score for HLH genes 138 listed above with all genes that connect to SARS-CoV-2 proteins through our assembled protein-139 protein interaction network (Fig. 2) .
    keywords: cov-2; covid-19; disease; genes; hlh; license; medrxiv; nets; network; preprint; proteins; sars
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        item: #5058 of 7819
          id: cord-319538-bawzonq1
      author: Krause, Martin
       title: Association between procalcitonin levels and duration of mechanical ventilation in COVID-19 patients
        date: 2020-09-18
       words: 2571
      flesch: 28
     summary: We aimed to identify if plasma procalcitonin levels on admission are associated with the duration of mechanical ventilation (primary outcome), 28-day mortality, and time to intubation (secondary outcomes) in a cohort of COVID-19 patients requiring mechanical ventilation. key: cord-319538-bawzonq1 authors: Krause, Martin; Douin, David J.; Tran, Timothy T.; Fernandez-Bustamante, Ana; Aftab, Muhammad; Bartels, Karsten title: Association between procalcitonin levels and duration of mechanical ventilation in COVID-19 patients date: 2020-09-18 journal: PLoS One DOI: 10.1371/journal.pone.0239174 sha: doc_id: 319538 cord_uid: bawzonq1 BACKGROUND: Patients diagnosed with COVID-19 frequently require mechanical ventilation.
    keywords: duration; level; patients; procalcitonin; ventilation
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        item: #5059 of 7819
          id: cord-319575-i5iq5qn4
      author: Ramachandran, R.
       title: Adding insult to injury: kidney replacement therapy during COVID-19 in India
        date: 2020-04-25
       words: 732
      flesch: 49
     summary: The majority of dialysis units are located in private hospitals. Moreover, dialysis centers are not willing Q4 to accept newly diagnosed end-stage renal disease patients or patients shifted from closed units as a result of panic and misinformation and insist that they produce a coronavirus Q5 test result.
    keywords: dialysis; patients
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        item: #5060 of 7819
          id: cord-319580-awtp0mpg
      author: McCartney, Stephen A.
       title: Obesity as a contributor to immunopathology in pregnant and non‐pregnant adults with COVID‐19
        date: 2020-08-11
       words: 3710
      flesch: 36
     summary: Annals of internal medicine The role of adipose tissue immune cells in obesity and low-grade inflammation Adipocytes properties and crosstalk with immune system in obesity-related inflammation Inflamed fat: what starts the fire? medRxiv Facing the noncommunicable disease (NCD) global epidemic--the battle of prevention starts in utero--the FIGO challenge Prevalence of Obesity and Severe Obesity Among Adults: United States Obesity is associated with worse outcomes in COVID-19: Analysis of Early Data From Severe obesity, increasing age and male sex are independently associated with worse in-hospital outcomes, and higher in-hospital mortality Obesity and COVID-19: an Italian snapshot Cytokine release syndrome in severe COVID-19 Clinical characteristics of 113 deceased patients with coronavirus disease 2019:
    keywords: cells; covid-19; disease; immune; obesity; patients; response; tissue; women
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        item: #5061 of 7819
          id: cord-319615-p2labgd8
      author: Schulman, Sam
       title: Coronavirus Disease 2019, Prothrombotic Factors, and Venous Thromboembolism
        date: 2020-05-11
       words: 3049
      flesch: 41
     summary: Most of the events (n ¼ 29) were in ICU patients and 21 of the 33 events were symptomatic with the remainder found through screening for DVT. 22 Stroke was also, albeit at a slightly lower incidence, diagnosed in sepsis patients remaining in sinus rhythm.
    keywords: care; covid-19; icu; incidence; patients; thromboembolism; venous
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        item: #5062 of 7819
          id: cord-319706-2e9jrv0s
      author: Ebinger, Joseph E.
       title: Pre-existing traits associated with Covid-19 illness severity
        date: 2020-07-23
       words: 4912
      flesch: 32
     summary: For the total sample of Covid-19 patients, we used parametric tests to compare normally distributed continuous variables and non-normally distributed or categorical variables, respectively. CONCLUSIONS AND RELEVANCE: In our healthcare system, greater Covid-19 illness severity is seen in patients who are older, male, African American, obese, with diabetes, and with greater overall comorbidity burden.
    keywords: age; care; covid-19; illness; intubation; male; patients; risk; severity; sex
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        item: #5063 of 7819
          id: cord-319707-j8y9gt2o
      author: Kato, Verstrepen
       title: Neurological manifestations of COVID-19, SARS and MERS
        date: 2020-06-19
       words: 3562
      flesch: 39
     summary: The impact of SARS on epilepsy: the experience of drug withdrawal in epileptic patients Neuromuscular disorders in severe acute respiratory syndrome A major outbreak of severe acute respiratory syndrome in Hong Kong Myopathic changes associated with severe acute respiratory syndrome: a postmortem case series The neuronal death induced by endotoxic shock but not that induced by excitatory amino acids requires TNF-alpha Local expression of inducible nitric oxide synthase in an animal model of neuropathic pain Infectious Etiologies of Rhabdomyolysis: three Case Reports and Review Rhabdomyolysis associated with probable SARS Olfactory neuropathy in severe acute respiratory syndrome: report of A case Strokes, thromboembolic events, and IVIg: rare incidents blemish an excellent safety record Large artery ischaemic stroke in severe acute respiratory syndrome (SARS) Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study Autonomic dysfunction in recovered severe acute respiratory syndrome patients Outcomes and prognostic factors in 267 patients with severe acute respiratory syndrome in Hong Kong Spontaneous intracranial hemorrhage in a patient with Middle East respiratory syndrome corona virus Neurological complications of middle east respiratory syndrome coronavirus: a report of two cases and review of the literature Neurologic syndrome due to MERS: is there a possibility that the virus can cross the blood-brain barrier to cause a neurological problem Clinical aspects and outcomes of 70 patients with middle east respiratory syndrome coronavirus infection: a single-center experience in Saudi Arabia Severe neurologic syndrome associated with Middle East respiratory syndrome corona virus (MERS-CoV) Pathology and pathogenesis of severe acute respiratory syndrome Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome Neurological Complications during Treatment of Middle East Respiratory Syndrome Peripheral neurotoxicity of pegylated interferon alpha. Indian journal of pediatrics Multiple organ infection and the pathogenesis of SARS Detection of severe acute respiratory syndrome coronavirus in the brain: potential role of the chemokine mig in pathogenesis Detection of SARS coronavirus RNA in the cerebrospinal fluid of a patient with severe acute respiratory syndrome
    keywords: articles; coronavirus; covid-19; manifestations; mers; patients; sars; syndrome
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        item: #5064 of 7819
          id: cord-319728-d0kf9gme
      author: Lucchini, Matteo
       title: Is serological response to SARS-CoV-2 preserved in MS patients on ocrelizumab treatment? A case report
        date: 2020-06-22
       words: 1384
      flesch: 42
     summary: key: cord-319728-d0kf9gme authors: Lucchini, Matteo; Bianco, Assunta; Giacomo, Paola Del; De Fino, Chiara; Nociti, Viviana; Mirabella, Massimiliano title: Is serological response to SARS-CoV-2 preserved in MS patients on ocrelizumab treatment? A case report date: 2020-06-22 journal: Mult Scler Relat Disord DOI: 10.1016/j.msard.2020.102323 sha: doc_id: 319728 cord_uid: d0kf9gme The emergency represented by the COVID-19 pandemic represents a new challenge for clinicians who deal with autoimmune diseases because of patients undergoing immunosuppressive therapy.
    keywords: covid-19; iga; ocrelizumab; patient
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        item: #5065 of 7819
          id: cord-319741-vgtd2whz
      author: Ranjan, Piyush
       title: Is excess weight a risk factor for the development of COVID 19 infection? A preliminary report from India
        date: 2020-09-09
       words: 1254
      flesch: 51
     summary: Studies suggest that in comparison to COVID-19 patients with normal body weight, obese patients are more likely to be critically ill, require mechanical ventilator support, and suffer increased complications and high mortality. A preliminary report from India date: 2020-09-09 journal: Diabetes Metab Syndr DOI: 10.1016/j.dsx.2020.09.012 sha: doc_id: 319741 cord_uid: vgtd2whz BACKGROUND AND AIM: This study explored the association between BMI and COVID-19 positive status in a tertiary care hospital from New Delhi.
    keywords: bmi; covid-19; obesity; patients
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        item: #5066 of 7819
          id: cord-319742-ypkt01rn
      author: Asgharpour, Masoumeh
       title: Effectiveness of extracorporeal blood purification (hemoadsorption) in patients with severe coronavirus disease 2019 (COVID-19)
        date: 2020-08-20
       words: 3502
      flesch: 36
     summary: The upper limit point of serum IL-6 level in COVID-19 patients who had no severe pneumonia was reported 24.3 pg/mL, and the increased expression of IL-6 in serum is expected to predict the severity of the COVID-19 pneumonia and a poor prognosis of patients [20] . Extracorporeal hemoadsorption could improve the general condition in most of recruited patients with severe coronavirus disease; however, large prospective multicenter trials in carefully selected patients are needed to definitely evaluate the efficacy of hemoperfusion in COVID-19 patients.
    keywords: blood; covid-19; cytokine; disease; extracorporeal; hemoperfusion; patients; study
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        item: #5067 of 7819
          id: cord-319780-rfj9t99r
      author: Alexander, S.P.H.
       title: A rational roadmap for SARS‐CoV‐2/COVID‐19 pharmacotherapeutic research and development. IUPHAR Review 29
        date: 2020-05-01
       words: 15233
      flesch: 30
     summary: A truncated version of human recombinant ACE2, lacking the transmembrane domain, mitigated against SARS-CoV infection of cells (Li et al., 2003) and has been used in animal models to reduce symptoms of severe acute lung failure , diabetic nephropathy (Oudit et al., 2010) and cardiac hypertrophy and fibrosis . It has been used to treat influenza A infection through targeting the M2 ion channel (Pinto et al., 1992; Wang et al., 1993; Holsinger et al., 1994) , although it is no longer recommended in the UK or US because of drug resistance (for review, see Li et al., 2015) .
    keywords: ace2; activity; acute; angiotensin; binding; cells; converting; coronavirus; cov-2; covid-19; domain; drug; entry; enzyme; et al; host; human; infection; inhibitors; interferon; membrane; mers; protease; protein; receptor; replication; review; rna; sars; sars coronavirus; spike; structure; syndrome; target; tmprss2
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        item: #5068 of 7819
          id: cord-319804-i5oprni9
      author: Mahajan, Ashutosh
       title: An Epidemic Model SIPHERD and its application for prediction of the spread of COVID-19 infection in India
        date: 2020-07-28
       words: 2757
      flesch: 50
     summary: Mathematical models for the epidemic have a major role to make predictions of the transmission dynamics of the disease and thus assist the authority to take necessary movements for the containment. India has reached the fourth position in the world in the number of confirmed COVID-19 cases and presently has 449,613 confirmed cases and 14,162 deaths as of June 23, 2020, which is really an alarming situation.
    keywords: cases; covid-19; india; model; number
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        item: #5069 of 7819
          id: cord-319805-b6ypt5d0
      author: Siepmann, Timo
       title: Association of history of cerebrovascular disease with severity of COVID-19
        date: 2020-08-06
       words: 5102
      flesch: 36
     summary: Investigation of early cohorts of COVID-19 patients in China focused on the effects of classic cardiovascular risk factors such as arterial hypertension and coronary heart disease or comorbidity in general [6, 7] . To approach this question, we assessed individual multicenter data from three cohorts of COVID-19 patients treated during the first months of the pandemic in Germany.
    keywords: covid-19; cvd; data; disease; history; patients; risk; severity; studies; study
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        item: #5070 of 7819
          id: cord-319823-sp5wibeh
      author: Brown, Sherry-Ann
       title: Innovation in Precision Cardio-Oncology During the Coronavirus Pandemic and Into a Post-pandemic World
        date: 2020-08-14
       words: 5153
      flesch: 17
     summary: Telemedicine for Covid-19 Virtual visits for care of patients with heart failure in the Era of COVID-19: a statement from the heart failure society of America COVID-19 Emergency Declaration Blanket Waivers for Health Care Providers A practical approach to the management of cancer patients during the novel coronavirus disease 2019 (COVID-19) pandemic: an international collaborative group Cardio-oncology care in the time of COVID-19 and the role of telehealth Transition to a virtual multidisciplinary tumor board during the COVID-19 pandemic: University of Pittsburgh experience Telehealth transformation: COVID-19 and the rise of virtual care Preventive behaviors conveyed on youtube to mitigate transmission of COVID-19: cross-sectional study The role of youtube and the entertainment industry in saving lives by educating and mobilizing the public to adopt behaviors for community mitigation of COVID-19: successive sampling design study Early epidemiological analysis of the coronavirus disease 2019 outbreak based on crowdsourced data: a population-level observational study Building trust while influencing online COVID-19 content in the social media world Mining physicians' opinions on social media to obtain insights into COVID-19: mixed methods analysis Measuring the outreach efforts of public health authorities and the public response on facebook during the COVID-19 pandemic in early 2020: cross-country comparison Global sentiments surrounding the COVID-19 pandemic on twitter: analysis of twitter trends Tracking social media discourse about the COVID-19 pandemic: development of a public coronavirus twitter data set Digital technology and COVID-19 Available online at Wearable devices for ambulatory cardiac monitoring: JACC state-of-the-art review Feasibility of a voice-enabled automated platform for medical data collection: cardioCube A protocol integrating remote patient monitoring patient reported outcomes and cardiovascular biomarkers Mobile health in cardiology: a review of currently available medical apps and equipment for remote monitoring Effectiveness of remote patient monitoring after discharge of hospitalized patients with heart failure: the better effectiveness after transition -heart failure (BEAT-HF) randomized clinical trial Impact of remote monitoring on clinical outcomes for patients with heart failure and atrial fibrillation: results from the REM-HF trial Assessment of heart failure patients' interest in mobile health apps for self-care: survey study Value of telemonitoring and telemedicine in heart failure management Wearable technology and how this can be implemented into clinical practice a mobile health platform to disseminate validated institutional measurements during the COVID-19 outbreak: utilizationfocused evaluation study Using mHealth to support COVID-19 education, self-assessment, and symptom monitoring: an observational study in The Netherlands COVID-19 contact tracing and data protection can go together Rapid implementation of a COVID-19 remote patient monitoring program HRS/EHRA/APHRS/LAHRS/ACC/AHA worldwide practice update for telehealth and arrhythmia monitoring during and after a pandemic A web-and app-based connected care solution for COVID-19 in-and outpatient care: qualitative study and application development Efficacy and safety of an mhealth app and wearable device in physical performance for patients with hepatocellular carcinoma: development and usability study A randomized controlled trial of a wearable technology-based intervention for increasing moderate to vigorous physical activity and reducing sedentary behavior in breast cancer survivors: the ACTIVATE trial The HOPE pilot study: harnessing patient-reported outcomes and biometric data to enhance cancer care Noninvasive vocal biomarker is associated with pulmonary hypertension Vocal biomarker is associated with hospitalization and mortality among heart failure patients Voice signal characteristics are independently associated with coronary artery disease Increasing physical activity amongst overweight and obese cancer survivors using an alexa-based intelligent agent for patient coaching: protocol for the physical activity by technology help (PATH) trial How Drones are Used for Life-Saving Healthcare 2020 The consequent exponentially increasing genetic knowledge combined with deep cardiovascular phenotyping of cancer patients may allow us to identify genetic variants predicting either increased susceptibility or tolerance for specific drug-induced cardiotoxicity and thereby to risk stratify patients based on their genetic backgrounds (84) .
    keywords: cancer; cardio; cardiovascular; care; covid-19; data; disease; health; heart; monitoring; oncology; pandemic; patients; survivors
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        item: #5071 of 7819
          id: cord-319837-5avoulan
      author: Raman, Eshwara V.
       title: Pediatric Airway Surgeries in COVID 19 Era
        date: 2020-07-27
       words: 1888
      flesch: 53
     summary: These recommendations have been made to help other pediatric airway surgeons to manage airway cases, however, this can be changed during this pandemic crisis though this can be changed later due to the evolving nature of COVID 19 and available evidence. key: cord-319837-5avoulan authors: Raman, Eshwara V.; Shivnani, Deepa title: Pediatric Airway Surgeries in COVID 19 Era date: 2020-07-27 journal: Indian J Otolaryngol Head Neck Surg DOI: 10.1007/s12070-020-01989-5 sha: doc_id: 319837 cord_uid: 5avoulan To outline a set of recommendations on the management of pediatric cases who requiring airway surgery in the context of COVID 19 pandemic.
    keywords: aerosol; airway; cases; covid; recommendations
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        item: #5072 of 7819
          id: cord-319849-3shr5grg
      author: Cheruiyot, Isaac
       title: Intracranial hemorrhage in coronavirus disease 2019 (COVID-19) patients
        date: 2020-11-03
       words: 3063
      flesch: 37
     summary: Cerebrovascular disease is associated with an increased disease severity in patients with coronavirus disease 2019 (COVID-19): a pooled analysis of published literature Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study Impact of cerebrovascular and cardiovascular diseases on mortality and severity of COVID-19-systematic review, meta-analysis, and meta-regression Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: an updated analysis Humanitas COVID-19 Task Force (2020) Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases Hypercoagulability of COVID-19 patients in intensive care unit: a report of thromboelastography findings and other parameters of hemostasis Thrombotic complications of patients admitted to intensive care with COVID-19 at a teaching hospital in the United Kingdom Acute ischemic stroke complicating common carotid artery thrombosis during a severe COVID-19 infection Hemorrhagic presentations of COVID-19: risk factors for mortality Stroke in patients with SARS-CoV-2 infection: case series Cerebrovascular disease in patients with COVID-19: a review of the literature and case series Neurologic manifestations in hospitalized patients with COVID-19: the ALBACOVID registry Status of SARS-CoV-2 in cerebrospinal fluid of patients with COVID-19 and stroke COVID-19-associated meningoencephalitis complicated with intracranial hemorrhage: a case report Hemorrhagic stroke and anticoagulation in COVID-19 Basal ganglia involvement and altered mental status: a unique neurological manifestation of coronavirus disease Neurologically devastating intraparenchymal hemorrhage in COVID-19 patients on extracorporeal membrane oxygenation: a case series Cerebrovascular disease in patients with COVID-19: neuroimaging, histological and clinical description A prospective clinical study of detailed neurological manifestations in patients with COVID-19 Acute cerebrovascular disease following COVID-19: a single center, retrospective, observational study Neurologic manifestations of hospitalized patients with coronavirus disease Coronavirus disease 2019 and stroke in Iran: a case series and effects on stroke admissions Letter to editor: severe brain haemorrhage and concomitant COVID-19 Infection: a neurovascular complication of COVID-19 Clinical and imaging characteristics in patients with SARS-CoV-2 infection and acute intracranial hemorrhage Neurological manifestations and COVID-19: Thereafter, a pooled analysis incorporating only cohort studies in which all hospitalized patients were studied within a specified period of time was conducted to estimate pooled incidence of intracranial hemorrhage in COVID-19 patients using the Meta-Analyst (software version 5.26.14, Center for Evidence-Based Medicine, Brown University, Providence, USA).
    keywords: case; covid-19; disease; hemorrhage; ich; patients; stroke; studies
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        item: #5073 of 7819
          id: cord-319851-mhnp42xo
      author: Cao, Xiaoling
       title: Authors’ response to letter by Fogacci, Borghi and Cicero, “Misinterpreting data in lipidology in the era of COVID-19”
        date: 2020-07-09
       words: 767
      flesch: 47
     summary: Hypolipidemia is associated with the severity of COVID-19 Low-density lipoprotein is a potential predictor of poor prognosis in patients with coronavirus disease 2019 Proteomic and Metabolomic Characterization of COVID-19 Proteomics of SARS-CoV-2-infected host cells reveals therapy targets Use of drug treatment for secondary prevention of cardiovascular disease in urban and rural communities of China: China Kadoorie Biobank Study of 0.5 million people Characterizing lipid profiles associated with asymptomatic intracranial arterial stenosis in rural-dwelling adults: A population-based study The concept of hypolipidemia was appropriately expanded and adapted in our report to describe the decreased cholesterol levels in COVID-19 patients.
    keywords: lipid; patients
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        item: #5074 of 7819
          id: cord-319853-jr8x5emx
      author: De Castro, Leonardo
       title: A fair allocation approach to the ethics of scarce resources in the context of a pandemic: The need to prioritize the worst‐off in the Philippines
        date: 2020-09-23
       words: 8509
      flesch: 50
     summary: In times of pandemic emergencies, anyone and everyone can be affected by the lack of safe and healthy housing suffered by disadvantaged sectors of society. This approach can be possible by focusing on removing barriers to inequitable access to healthcare communication and other healthcare resources, an important strategy in support of the prioritization of the worst off.
    keywords: access; country; covid-19; emergency; health; healthcare; information; measures; need; normal; pandemic; patients; people
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        item: #5075 of 7819
          id: cord-319859-6mt34av6
      author: Zhou, Min
       title: Research on the individualized short‐term training model of nurses in emergency isolation wards during the outbreak of COVID‐19
        date: 2020-08-04
       words: 2731
      flesch: 45
     summary: Hopefully, this study could provide theoretical basis for training nurses under emergency assistance of COVID-19 and we also hope to work with nursing colleagues around the world with an open attitude to save more patients. Emergency training of nursing staff is crucial on preventing the spread of the COVID-19 epidemic effectively and ensuring the operation of emergency isolation ward orderly.
    keywords: covid-19; emergency; isolation; nurses; nursing; online; staff; training
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        item: #5076 of 7819
          id: cord-319860-zouscolw
      author: Wu, Jianhua
       title: Place and causes of acute cardiovascular mortality during the COVID-19 pandemic
        date: 2020-09-28
       words: 3875
      flesch: 50
     summary: ► Home death had the greatest increase in excess acute CV death, and the most frequent cause of acute CV death during this period was stroke, followed by acute coronary syndrome. CV events directly leading to death (herein called acute CV deaths) were categorised as acute coronary syndrome (ST-elevation myocardial infarction (STEMI), non-STEMI, type 2 myocardial infarction, reinfarction) abbreviated as acute coronary syndrome, heart failure, cardiac arrest, ventricular tachycardia (VT) and/ or ventricular fibrillation (VF), stroke (acute ischaemic stroke, acute haemorrhagic stroke, other non-cerebral strokes, unspecified stroke), cardiogenic shock, pulmonary embolism, deep venous thrombosis, aortic disease (aortic aneurysm rupture and aortic dissection) and infective endocarditis (online supplemental table 1).
    keywords: acute; covid-19; deaths; excess; hospital; mortality; pandemic
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        item: #5077 of 7819
          id: cord-319865-g3qxu6uv
      author: Frountzas, Maximos
       title: Personal protective equipment against COVID-19: Vital for surgeons, harmful for patients?
        date: 2020-09-21
       words: 1310
      flesch: 37
     summary: Moreover, another study of 43 healthcare workers, that used PPE for 8.76 ± 2.31 hours per day during management of COVID-19 patients, outlined various PPE-induced dermatoses, such as pressure injury, contact dermatitis, pressure urticaria and exacerbation of pre-existing skin diseases. Systematic review of recommended operating room practice during the COVID-19 pandemic Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans International Guidelines And Recommendations For Surgery During Covid-19 Pandemic: A Systematic Review Pre-operative COVID-19 testing and decolonization Surgery during the COVID-19 pandemic: A comprehensive overview and perioperative care Precautions for operating room team members during the COVID-19 pandemic Personal Protective Equipment and COVID-19: A Review for Surgeons Surgery during the COVID-19 pandemic: operating room suggestions from an international Delphi process Headaches associated with personal protective equipment-a cross-sectional study amongst frontline healthcare workers during COVID-19 (HAPPE study) Personal protective equipment induced facial dermatoses in healthcare workers managing COVID-19 cases Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin:
    keywords: covid-19; ppe; surgeons; surgery
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        item: #5078 of 7819
          id: cord-319868-rtt9i7wu
      author: Majeed, Taban
       title: Issues associated with deploying CNN transfer learning to detect COVID-19 from chest X-rays
        date: 2020-10-06
       words: 7684
      flesch: 47
     summary: As such, it becomes highly desired and required to have computeraided diagnostic systems that can aid radiologists in making a more time-efficient and accurate interpretation of X-ray images that are characteristic of COVID-19 [4] . in [5] proposed a method to detect COVID-19 using X-ray images based on deep feature and support vector machines (SVM).
    keywords: architectures; cases; chest; classification; cnn; cnns; covid-19; images; learning; models; ray; rays
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        item: #5079 of 7819
          id: cord-319876-psilbis0
      author: Zhu, Jian
       title: COVID-19 Epidemic: Clinical Characteristics of Patients in Pediatric Isolation Ward
        date: 2020-07-09
       words: 2428
      flesch: 53
     summary: In order to accurately admit children with COVID-19 to an isolation ward, our study retrospectively analyzed the clinical characteristics of children in isolation wards during the COVID-19 epidemic. 4, 5 It is mentioned that medical institutions should set up isolation wards.
    keywords: cases; children; coronavirus; covid-19; isolation; ward
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        item: #5080 of 7819
          id: cord-319885-8qyavs7m
      author: Chan, Stephen
       title: Count regression models for COVID-19
        date: 2021-02-01
       words: 3366
      flesch: 47
     summary: The best fitting count regression model for modelling the number of new daily COVID-19 cases of all countries analysed was shown to be a negative binomial distribution with log link function. In particular, the UK and Vietnam have the largest and smallest slope estimates, respectively, hence the rate of increase in new daily COVID-19 cases with time is the highest for the UK and lowest for Vietnam. .
    keywords: cases; china; countries; covid-19; data; models; number
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        item: #5081 of 7819
          id: cord-319899-nso0ob27
      author: Wilke, Jan
       title: Restrictercise! Preferences Regarding Digital Home Training Programs during Confinements Associated with the COVID-19 Pandemic
        date: 2020-09-07
       words: 2263
      flesch: 34
     summary: Manag Adherence to and efficacy of home exercise programs to prevent falls: A systematic review and meta-analysis of the impact of exercise program characteristics How do care-provider and home exercise program characteristics affect patient adherence in chronic neck and back pain: A qualitative study Activity and health during the SARS-CoV2 pandemic (ASAP): Study protocol for a multi-national network trial Validation of the NPAQ-short-A brief questionnaire to monitor physical activity and compliance with the WHO recommendations Health benefits of physical activity a systematic review of current systematic reviews Physical activity for immunity protection: Our survey with 15,261 participants (38 ± 15 years, 58.5% females) examined preferences towards digital home exercise programs in 14 countries affected by COVID-19.
    keywords: activity; covid-19; exercise; home; pandemic; training
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        item: #5082 of 7819
          id: cord-319908-10b7de22
      author: Naser, Abdallah Y
       title: Knowledge and practices towards COVID-19 during its outbreak: a multinational cross-sectional study
        date: 2020-04-17
       words: 3994
      flesch: 47
     summary: The current study showed that knowledge scores significantly differed across marital status categories (P<0.002), divorced participants had a significant negative association with COVID-19 knowledge score (p<0.01). Multiple linear regression analysis was used to identify predictors of COVID-19 knowledge.
    keywords: covid-19; knowledge; license; medrxiv; participants; practices; preprint; study
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        item: #5083 of 7819
          id: cord-319910-s2e56ety
      author: Jani, B. D.
       title: Comparison of COVID-19 outcomes among shielded and non-shielded populations: A general population cohort study of 1.3 million
        date: 2020-09-21
       words: 4345
      flesch: 52
     summary: The two groups 20 have been labelled high risk, highest risk or clinically extremely vulnerable and moderate 21 risk, at risk or clinically vulnerable by various UK organisations. Referent to low-risk, the shielded group had higher risk of confirmed infection (RR 7.91, 95% 7.01-8.92), case-fatality (RR 5.19, 95% CI 4.12-6.53) and population mortality (RR 48.64, 95% 37.23-63.56).
    keywords: covid-19; criteria; license; population; preprint; risk; table
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        item: #5084 of 7819
          id: cord-319912-fc9tmx96
      author: Ciminelli, Gabriele
       title: COVID-19 in Italy: An Analysis of Death Registry Data
        date: 2020-09-16
       words: 3281
      flesch: 55
     summary: Strikingly, excess deaths were higher than official fatalities throughout the end of April, suggesting that COVID-19 deaths might have been vastly underreported in official statistics. Discounting indirect deaths, we calculate that COVID-19 deaths may have been 60% higher than what was officially reported.
    keywords: covid-19; data; deaths; epidemic; mortality; municipalities; nursing
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        item: #5085 of 7819
          id: cord-319920-vn5si7xm
      author: Sampogna, Gianluca
       title: Spinal cord dysfunction after COVID-19 infection
        date: 2020-09-30
       words: 2539
      flesch: 44
     summary: Spinal Cord Atypical presentation of Covid-19 in persons with spinal cord injury The 2019 revision of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)-what's new? Updating and validating the charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries The Catz-Itzkovich SCIM: a revised version of the spinal cord independence measure Clinical characteristics and diagnostic challenges of pediatric COVID-19: a systematic review and meta-analysis Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan COVID-19 and Kawasaki disease: novel virus and novel case COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up COVID-19 and its implications for thrombosis and anticoagulation Neurologic manifestations of hospitalized patients with coronavirus disease Neurologic features in severe SARS-CoV-2 infection Guillain-Barré syndrome associated with SARS-CoV-2 COVID-19 and spinal cord injuries: the viewpoint from an emergency department resident with quadriplegia COVID-19 tsunami: the first case of a spinal cord injury patient in Italy COVID-19 and spinal cord injury and disease: results of an international survey COVID-19: screening and triage challenges in people with disability due to spinal cord injury Let's conquer COVID-19 and sustain our abilities Clinical features of coronavirus disease 2019 (COVID-19) in a cohort of patients with disability due to spinal cord injury Patients with cardiovascular, pulmonary, and immunological diseases showed severe COVID-19 presentations.
    keywords: case; cord; covid-19; sars; scd; spinal
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        item: #5086 of 7819
          id: cord-319930-ymqnb54a
      author: Kremer, Stéphane
       title: Brain MRI Findings in Severe COVID-19: A Retrospective Observational Study
        date: 2020-06-16
       words: 3190
      flesch: 30
     summary: N is the total number of patients with available data, and n the number of positive patients. Describe the neuroimaging findings (excluding ischemic infarcts) in patients with severe COVID-19 infection.
    keywords: brain; covid-19; data; flair; hemorrhagic; lesions; mri; patients
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        item: #5087 of 7819
          id: cord-319983-e4f2sfl4
      author: Tripathi, Shweta
       title: The COVID-19: Current understanding
        date: 2020-09-26
       words: 4301
      flesch: 48
     summary: Recent studies from China and France observed that the administration of this drug in COVID-19 patients produced significant results in both clinical outcomes as well as in viral clearance Recently a medical practitioner from Shanghai used plasma therapy to treat COVID-19 patients and yielded positive results with rapid recovery, suggesting it could be a potential treatment for COVID-19 patients.
    keywords: china; coronavirus; cov-2; covid-19; disease; india; novel; patients; sars; treatment
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        item: #5088 of 7819
          id: cord-319998-dkk2motm
      author: Ho, Jing-Mao
       title: Unequal discourses: Problems of the current model of world health development
        date: 2020-09-09
       words: 2485
      flesch: 43
     summary: The World Health Organization (WHO) has been regarded as playing an important role in advancing global health development (Brown, Cueto, & Fee, 2006; Magnusson, 2007; Ruger & Yach, 2009) , however it is no stranger to calls for institutional reform. The current model of global health development has been criticized for its imperialist tendency (Levich, 2015) and the dominant role of state actors (Adams, Behague, Caduff, Löwy, & Ortega, 2019; McInnes et al., 2020) .
    keywords: china; covid-19; ebola; global; health; world
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        item: #5089 of 7819
          id: cord-320022-e3ti4doi
      author: Lee, Jin
       title: Do We Really Need to Isolate All Children with COVID-19 in Healthcare Facilities?
        date: 2020-07-22
       words: 1369
      flesch: 37
     summary: To minimize these disadvantages in children, home isolation should be adopted as early treatment sites like many other countries. [7] [8] [9] The policies in Korea do not allow infected people who are asymptomatic or those with mild symptoms to choose where he or she will be placed under isolation, which could raise human rights issues.
    keywords: covid-19; isolation; symptoms; test
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        item: #5090 of 7819
          id: cord-320025-omz1fou9
      author: Di Girolamo, Nicola
       title: Characteristics of scientific articles on COVID-19 published during the initial 3 months of the pandemic
        date: 2020-07-24
       words: 5563
      flesch: 43
     summary: Also, only a negligible number of published articles reports limitations in the abstracts, hindering a rapid interpretation of their shortcomings. Half of the included articles, (578, 49.6%) came from 49 individual journals (range of published articles per journal, 5-70).
    keywords: articles; covid-19; human; number; pandemic; primary; research; studies; study
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        item: #5091 of 7819
          id: cord-320031-e328fesl
      author: Loforte, Antonio
       title: Veno-venous Extracorporeal Membrane Oxygenation Support in COVID-19 Respiratory Distress Syndrome: Initial Experience
        date: 2020-06-01
       words: 1674
      flesch: 47
     summary: 7,8 Our small sample of COVID-19 ECMO patients presented young age and showed no severe comorbidities but severe ARDS occurred in all of them. 2, [6] [7] [8] Regarding oxygenation, ECMO blood flow was maximized to reduce the FIO2 less than 0.6 and maintain hemoglobin Veno-venous Extracorporeal Membrane Oxygenation Support in COVID-19 Respiratory Distress Syndrome: Initial Experience saturation more than 85%.
    keywords: blood; covid-19; ecmo; patients; pressure; support
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        item: #5092 of 7819
          id: cord-320045-qhk01o9m
      author: Gralnek, Ian M.
       title: ESGE and ESGENA Position Statement on gastrointestinal endoscopy and the COVID-19 pandemic
        date: 2020-04-17
       words: 3435
      flesch: 35
     summary: Jewelry (watches, rings, bracelets) should not be worn by GI endoscopy unit HCP. Urgent/emergent procedure Appropriate PPE (see Table 2 ) Elective procedure Low risk of COVID-19 High risk of confirmed COVID-19 Higher risk of GI disease-related morbidity/mortality Evaluate morbidity/mortality risk of GI disease vs. risk of COVID-19 See Figure 2 Higher risk of COVID-19-related morbidity/mortality Pre-procedure Risk Management 1. The following list of GI endoscopy procedures should always be performed (▶ Fig. 2 ) ▪ Acute upper/lower GI bleeding with hemodynamic instability ▪ Capsule/enteroscopy for urgent/emergent bleeding ▪ Anemia with hemodynamic instability ▪ Foreign body in esophagus and/or high-risk foreign body in the stomach ▪ Obstructive jaundice ▪ Acute ascending cholangitis 3.
    keywords: covid-19; endoscopy; infection; pandemic; patients; procedures; risk
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        item: #5093 of 7819
          id: cord-320063-n9qzbnup
      author: Calender, Alain
       title: Modeling Potential Autophagy Pathways in COVID-19 and Sarcoidosis
        date: 2020-08-10
       words: 1596
      flesch: 28
     summary: We hypothesize that the defect in autophagy observed in sarcoidosis patients might also decrease the traffic of viral RNA into vesicles for viral infections, similarly to what might be observed for nanoparticles in experimental mouse models. Human Coronavirus: Host-Pathogen Interaction Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression Exome sequencing and pathogenicity-network analysis of five French families implicate mTOR signalling and autophagy in familial sarcoidosis Autophagy and Gastrointestinal Diseases Patients with interstitial lung disease and pulmonary sarcoidosis are at high risk for severe illness related to COVID-19 The anti-HIV drug nelfinavir mesylate (Viracept) is a potent inhibitor of cell fusion caused by the SARSCoV-2 spike (S) glycoprotein warranting further evaluation as an antiviral against COVID-19 infections Pulmonary Pathology of Early-Phase 2019 Novel Coronavirus (COVID-19) Pneumonia in Two Patients With Lung Cancer COVID-19 spike-host cell receptor GRP78 binding site prediction Interferon-Stimulated Genes as Enhancers of Antiviral Innate Immune Signaling The spectrum of opportunistic diseases complicating sarcoidosis New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19? Azithromycin treats diffuse panbronchiolitis by targeting T cells via inhibition of mTOR pathway Antituberculous drugs modulate bacterial phagolysosome avoidance and autophagy in Mycobacterium tuberculosis-infected macrophages 2 FIGURE LEGEND Figure 1.
    keywords: autophagy; cov2; covid-19; infection; sarcoidosis; sars
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        item: #5094 of 7819
          id: cord-320064-kjvfe8sv
      author: Soeroto, Arto Yuwono
       title: Effect of increased BMI and obesity on the outcome of COVID-19 adult patients: A systematic review and meta-analysis
        date: 2020-09-28
       words: 3333
      flesch: 49
     summary: COVID-19 patients with composite poor outcome had higher BMI with mean difference 1.12 (95% CI, 0.67–1.57, P < 0.001). On the other hand, COVID-19 patients with composite poor outcome have higher BMI.
    keywords: analysis; bmi; covid-19; meta; obesity; outcome; patients; studies
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        item: #5095 of 7819
          id: cord-320065-zxh8u4eg
      author: Patel, Pious D.
       title: Tracking the Volume of Neurosurgical Care during the COVID-19 Pandemic
        date: 2020-06-27
       words: 1873
      flesch: 47
     summary: Neurosurgical volume was compared between these periods. The long-term impacts of reduced neurosurgical volume and increased telehealth utilization on patient outcomes should be explored.
    keywords: covid-19; pandemic; procedures; visits; volume
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        item: #5096 of 7819
          id: cord-320067-929h6arn
      author: Facheris, Paola
       title: Complicated coronavirus disease 2019 (COVID‐19) in a psoriatic patient treated with ixekizumab
        date: 2020-06-18
       words: 328
      flesch: 45
     summary: MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)? key: cord-320067-929h6arn authors: Facheris, Paola; Valenti, Mario; Pavia, Giulia; Gargiulo, Luigi; Narcisi, Alessandra; Costanzo, Antonio; Borroni, Riccardo G. title: Complicated coronavirus disease 2019 (COVID‐19) in a psoriatic patient treated with ixekizumab date: 2020-06-18 journal:
    keywords: covid-19; pneumonia
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        item: #5097 of 7819
          id: cord-320082-gbli8zn2
      author: Zadnik, Vesna
       title: Impact of COVID-19 on Cancer Diagnosis and Management in Slovenia – Preliminary Results
        date: 2020-07-29
       words: 3165
      flesch: 41
     summary: Many cancer experts have highlighted the problem of access to and utilisation of cancer care services during and after the COVID-19 pandemic. For example, projections for the US show that cumulative excess deaths from colorectal and breast cancers between 2020 and 2030 could be around 1% 18 , highlighting the need for extreme caution when deciding on what measures to adopt if/when subsequent surges in COVID-19 cases occur so as to not significantly disrupt cancer control services also in the future.
    keywords: cancer; control; covid-19; referrals; visits
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        item: #5098 of 7819
          id: cord-320092-0qnvydux
      author: Ehsani, Sepehr
       title: COVID-19 and iron dysregulation: distant sequence similarity between hepcidin and the novel coronavirus spike glycoprotein
        date: 2020-10-16
       words: 7552
      flesch: 37
     summary: Hypoferremia predicts hospitalization and oxygen demand in COVID-19 patients HAMP promoter hypomethylation and increased hepcidin levels as biomarkers for Kawasaki disease Human coronaviruses OC43 and HKU1 bind to 9-O-acetylated sialic acids via a conserved receptor-binding site in spike protein domain a The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis COVID-19 and Kawasaki disease: novel virus and novel case Hepcidin revisited, disulfide connectivity, dynamics, and structure Mechanisms of virus membrane fusion proteins Chondrostean sturgeon hepcidin: an evolutionary link between teleost and tetrapod hepcidins Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity A dynamic COVID-19 immune signature includes associations with poor prognosis Intracellular iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections Post-translational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furin Hepatobiliary pathology Structure, function, and evolution of coronavirus spike proteins Rethinking living fossils Palmitoylation: policing protein stability and traffic Characterization and functional analysis of liver-expressed antimicrobial peptide-2 (LEAP-2) from golden pompano Trachinotus ovatus (Linnaeus 1758) Protein sequence: A unique but restricted sequence similarity exists between mature hepcidin and the cysteine-rich cytoplasmic tail of coronavirus spike proteins.
    keywords: coronavirus; coronavirus spike; covid-19; disease; domain; ferroportin; hepcidin; human; iron; levels; patients; protein; sars; sequence; similarity; spike; structure
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        item: #5099 of 7819
          id: cord-320100-kyvje05n
      author: Zingone, Fabiana
       title: No Need of Transforming Gastroenterology Units to COVID Units at the Time of SARS-COV2 Infection - A Single-Center Analysis from Northern Italy
        date: 2020-05-15
       words: 903
      flesch: 30
     summary: Endoscopy units and the COVID-19 Outbreak: A Multi-Center Experience from Italy Inflammatory bowel diseases and COVID-19: the invisible enemy Viral screening before initiation of biologics in patients with inflammatory bowel disease during the COVID-19 outbreak Screening for active COVID-19 infection and immunization status prior to biologic therapy in IBD patients at the time of the pandemic outbreak. This approach has been corroborated by the fact that only 5 out of about 700 of our patients on biologic therapy were diagnosed with COVID-19 infection, and none of our 135 patients with eosinophilic gastrointestinal disorders on active treatment.
    keywords: covid-19; patients
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        item: #5100 of 7819
          id: cord-320104-cgzqwbzs
      author: Lester, Paula E.
       title: Policy Recommendations regarding Skilled Nursing Facility Management of COVID-19: Lessons From New York State
        date: 2020-06-02
       words: 584
      flesch: 44
     summary: The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome Famotidine Trial Underway in NYC for COVID-19 Treatment Preparing for COVID 19; long term care facilities, nursing homes More than 1,700 previously undisclosed deaths at NY nursing homes COVID-19 Preparedness in Nursing Homes in the Midst of the Pandemic Estimates of the severity of coronavirus disease 2019: a model-based analysis key: cord-320104-cgzqwbzs authors: Lester, Paula E.; Holahan, Timothy; Siskind, David; Healy, Elaine title: Policy Recommendations regarding Skilled Nursing Facility Management of COVID-19: Lessons From New York State date: 2020-06-02 journal: J Am Med Dir Assoc DOI: 10.1016/j.jamda.2020.05.058 sha: doc_id: 320104 cord_uid: cgzqwbzs ABSTRACT To provide policy recommendations for managing COVID-19 in Skilled Nursing Facilities (SNFs), a group of certified medical directors from several facilities in New York state with experience managing the disease used email, phone, and video conferencing to develop consensus recommendations.
    keywords: covid-19; snf
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        item: #5101 of 7819
          id: cord-320127-55h4hhm3
      author: Mazingi, Dennis
       title: Mitigating the impact of COVID-19 on children's surgery in Africa
        date: 2020-06-10
       words: 2671
      flesch: 36
     summary: 13 16 There is a risk of healthcare resources being diverted away from surgical care, potentially impeding progress towards global surgery goals for 2030. New York: United Nations, Department of Economic and Social Affairs, Population Division COVID-19 preparedness within the surgical, obstetric and anesthetic ecosystem in sub Saharan Africa Correspondence from northern Italy about our experience with COVID-19 From the editors: the COVID-19 crisis and its implications for pediatric surgeons Global guidance for surgical care during the COVID-19 pandemic Global surgery 2030: evidence and solutions for achieving health, welfare, and economic development Letter to the editor: cancellation of elective surgery during the COVID-19 pandemic SSZ COVID-19 Subcommittee.
    keywords: africa; children; covid-19; health; hospital; pandemic; sars; surgical
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        item: #5102 of 7819
          id: cord-320136-k4204pb6
      author: Razum, Oliver
       title: Covid-19 in Flüchtlingsunterkünften: ÖGD jetzt weiter stärken
        date: 2020-04-23
       words: 3327
      flesch: 32
     summary: Juni und Dezember 2016 etwa knapp die Hälfte der befragten Geflüchteten in Sammelunterkünften Auf der Website der Beauftragten der Bundesregierung für Migration, Flüchtlinge und Integration https://www.integrationsbeauftragte.
    keywords: auch; auf; bei; covid-19; das; der; des; die; ein; eine; einrichtungen; für; geflüchtete; health; innen; ist; können; management; mit; nicht; oder; sammelunterkünften; sich; sie; sind; sowie; und; von; werden; wie; zur; ögd
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        item: #5103 of 7819
          id: cord-320139-yfm640jl
      author: Sun, R.
       title: Dépistage systématique de l’épidémie à coronavirus 2019 en radiothérapie par scanographie thoracique et PCR : expérience d’un centre
        date: 2020-10-31
       words: 1731
      flesch: 49
     summary: Deux décès (soit 7 %) imputables à la COVID-19 ont été à déplorer. Les données relatives à la survenue d’une COVID-19 en cours de radiothérapie ont aussi été recueillies afin d’estimer l’incidence des cas de COVID-19 dans le service de radiothérapie.
    keywords: des; les; radiothérapie; sur; une; été
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        item: #5104 of 7819
          id: cord-320145-582kmoyo
      author: Cardinal, R. N.
       title: Simulating a community mental health service during the COVID-19 pandemic: effects of clinician-clinician encounters, clinician-patient-family encounters, symptom-triggered protective behaviour, and household clustering
        date: 2020-05-03
       words: 5486
      flesch: 43
     summary: Instead, we focus on infection rates (including clinician infection rates) and discuss other potential effects of the service-level manipulations examined. Under our assumptions, these service arrangements had only a very small impact on infection rates across the population studied (clinicians, patients, and family together; Figure 2A,C) , but some had a substantial effect on clinician infection rates (Figures 2B,D) .
    keywords: clinician; contact; effect; family; infection; license; patients; preprint; rates; transmission
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        item: #5105 of 7819
          id: cord-320147-29a7njqi
      author: Mendes, Luís
       title: How Can We Quarantine Without a Home? Responses of Activism and Urban Social Movements in Times of COVID‐19 Pandemic Crisis in Lisbon
        date: 2020-06-23
       words: 8414
      flesch: 29
     summary: In this context and focusing specifically on the Portuguese case, the resurgence of popular protest and new urban social movements not only continued to be primarily associated to the anti-austerity ideology, as gave a new impetus to collective action in the field of struggles for the right to housing and the city. Despite their weak capacity for mobilisation, their limited and fleeting character, the truth is that new urban social movements often include social and political innovation, as they aim at 'transformative' changes and new responses that imply transformation in power relations in the contemporary city.
    keywords: action; capitalist; city; collective; covid-19; crisis; emergency; housing; lisbon; measures; movements; pandemic; public; right; social; state; struggles; urban
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        item: #5106 of 7819
          id: cord-320149-3q4q98a6
      author: Di Carlo, Davide Tiziano
       title: Exploring the clinical association between neurological symptoms and COVID-19 pandemic outbreak: a systematic review of current literature
        date: 2020-08-01
       words: 3485
      flesch: 33
     summary: An official clinical practice guideline of the The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses COVID-19 in a designated infectious diseases hospital outside Hubei Province COVID-19 with different severity: a multi-center study of clinical features Self-reported olfactory and taste disorders in SARS-CoV-2 patients: a cross-sectional study Olfactory and gustatory dysfunctions as a clinical presentation of mildto-moderate forms of the coronavirus disease (COVID-19): a multicenter European study The clinical and chest CT features associated with severe and critical COVID-19 pneumonia Clinical characteristics of 225 patients with COVID-19 in a tertiary Hospital near Wuhan Characteristics of COVID-19 infection in Beijing Clinical features and treatment of COVID-19 patients in northeast Chongqing Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series Characteristics of emergency department patients with COVID-19 at a single site in Northern California: clinical observations and public health implications Clinical characteristics and outcomes of COVID-19 patients with a history of stroke in Wuhan China COVID-19 related neuroimaging findings: a signal of thromboembolic complications and a strong prognostic marker of poor patient outcome Imaging in neurological disease of hospitalized COVID-19 patients: an Italian multicenter retrospective observational study Brain imaging use and findings in COVID-19: a single academic center experience in the epicenter of disease in the United States Acute-onset smell and taste disorders in the context of COVID-19: a pilot multicentre polymerase chain reaction based case-control study Human Coronaviruses: respiratory pathogens revisited as infectious neuroinvasive, neurotropic, and neurovirulent agents Middle East respiratory syndrome Nervous system involvement after infection with COVID-19 and other coronaviruses The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2 Minireview: overview of the renin-angiotensin system-an endocrine and paracrine system Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways Multiple organ infection and the pathogenesis of SARS Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 First case of 2019 novel coronavirus disease with encephalitis The neuroinvasive potential of SARS-CoV2 may be at least partially responsible for the respiratory failure of COVID-19 patients Respiratory failure alone does not suggest central nervous system invasion by SARS-CoV-2 Reninangiotensin system: an old player with novel functions in skeletal muscle A first case of meningitis/encephalitis associated with SARS-Coronavirus-2 COVID-19-associated meningoencephalitis complicated with intracranial hemorrhage: a case report MERS-CoV infection in humans is associated with a pro-inflammatory Th1 and Th17 cytokine profile Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Characteristics of ischaemic stroke associated with COVID-19 COVID-19 presenting as stroke Stroke epidemiology: advancing our understanding of disease mechanism and therapy Hospitalization for infection and risk of acute ischemic stroke: the Cardiovascular Health Study Guillain-Barré syndrome associated with SARS-CoV-2 Early Guillain-Barré syndrome in coronavirus disease 2019 (COVID-19): a case report from an Italian COVID-hospital Miller Fisher syndrome and polyneuritis cranialis in COVID-19 Guillain Barre syndrome associated with COVID-19 infection: a case report Acute symptomatic seizures in critically Ill patients with COVID-19: is there an association? Data were obtained for the whole population and subsequently we divided it into two groups: severe patients and non-severe patients, according to the American Thoracic Society guidelines for community-acquired pneumonia
    keywords: clinical; coronavirus; covid-19; disease; infection; patients; sars; studies; syndrome
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        item: #5107 of 7819
          id: cord-320158-6dh9e5rg
      author: Hansen, Richard
       title: Adaptations to the current ECCO/ESPGHAN guidelines on the management of paediatric acute severe colitis in the context of the COVID-19 pandemic: a RAND appropriateness panel
        date: 2020-09-01
       words: 5608
      flesch: 34
     summary: Clinical features of patients infected with 2019 novel coronavirus in Wuhan ) from the paediatric IBD Porto group of European Society of paediatric gastroenterology, hepatology, and nutrition SECURE-IBD registry: surveillance epidemiology of coronavirus (COVID-19) under research exclusion but not TNF antagonists, are associated with adverse COVID-19 outcomes in patients with inflammatory bowel diseases: results from an international registry gastroenterology Adaptations to the British Society of gastroenterology guidelines on the management of acute severe Uc in the context of the COVID-19 pandemic: a Rand appropriateness panel Management of paediatric ulcerative colitis, part 2: acute severe Colitis-An evidence-based consensus guideline from the European Crohn's and colitis organization and the European Society of paediatric gastroenterology, hepatology and nutrition SEaRCH™ expert panel process: streamlining the link between evidence and practice The RAND/UCLA Appropriateness Method User's Manual Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 P116 the occurrence of venous thromboembolisms in paediatric-onset IBD Combination of oral antibiotics may be effective in severe pediatric ulcerative colitis: a preliminary report Antibiotic cocktail for pediatric acute severe colitis and the microbiome: the PRASCO randomized controlled trial Severe pediatric ulcerative colitis: a prospective multicenter study of outcomes and predictors of response Effect of dexamethasone in hospitalized patients with COVID-19: preliminary report COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study Outcomes of COVID-19 in 79 patients with IBD in Italy: an IG-IBD study Increased incidence of systemic serious viral infections in patients with inflammatory bowel disease associates with active disease and use of thiopurines Acute kidney injury in SARS-CoV-2 infected patients COVID-19: consider cytokine storm syndromes and immunosuppression Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed Outcome following thiopurine use in children with ulcerative colitis: a prospective multicenter registry study Safety of thiopurine therapy in inflammatory bowel disease: long-term follow-up study of 3931 patients British Society of gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: an updated analysis Incidence of venous thromboembolism in hospitalized patients with COVID-19 Anticoagulant therapy in pediatrics Covid-19 and thrombosis: what do we know about the risks and treatment? Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional, multicenter study Correlation of chest CT and RT-PCR testing for coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained. In addition, it has become evident that a delay in initiating therapy is likely to have a detrimental effect on paediatric patients with IBD.
    keywords: asc; cov-2; covid-19; paediatric; panel; patients; rand; sars; swab; therapy
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        item: #5108 of 7819
          id: cord-320208-uih4jf8w
      author: Li, Diya
       title: Modeling Spatiotemporal Pattern of Depressive Symptoms Caused by COVID-19 Using Social Media Data Mining
        date: 2020-07-10
       words: 8953
      flesch: 53
     summary: We assessed the level of stress expressed in COVID-19 related tweets by integrating a lexicon-based method derived from established clinical assessment questionnaire PHQ-9 Even though our datasets were preprocessed and selected with entities on COVID-19 related topic, some of the tweets might be outside of the topic or are influenced by other objective factors.
    keywords: accuracy; algorithm; analysis; assessment; covid-19; data; number; phq; results; stress; symptoms; topic; tweets; twitter; words
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        item: #5109 of 7819
          id: cord-320247-123v1ddf
      author: Sheng, Wang-Huei
       title: SARS-CoV-2 and COVID-19
        date: 2020-04-03
       words: 958
      flesch: 49
     summary: The preventive strategies of community hospital in the battle of fighting pandemic COVID-19 in Taiwan Interrupting COVID-19 transmission by implementing enhanced traffic control bundling: implications for global prevention and control efforts Internationally lost COVID-19 cases Evolving reporting criteria of COVID-19 in Taiwan during the epidemic Response to COVID-19 in Taiwan: big data analytics, new technology, and proactive testing The already available data suggested that the 2019-nCoV may be less pathogenic than the MERS-CoV and SARS-CoV. However, the rapidly increasing number of COVID-19 cases suggests that this virus might transmit more effectively among humans compared to prior strains of coronavirus and that mild illness might be quite common in infected individuals.
    keywords: cases; covid-19; taiwan
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        item: #5110 of 7819
          id: cord-320262-9zxgaprl
      author: Asamoah, Joshua Kiddy K.
       title: Global stability and cost-effectiveness analysis of COVID-19 considering the impact of the environment:using data from Ghana
        date: 2020-07-10
       words: 3661
      flesch: 50
     summary: It is further inferred from this 310 study that; applying optimal control strategy on the rate at which the virus is released into the system, m 1 311 and m 2 , and also on the relative transmission rate due to human behaviour will considerably strike down 312 COVID-19 pandemic. Modelling of rabies transmission dynamics 477 using optimal control analysis Optimal control applied to biological models Optimal COVID-19 quarantine and testing policies Controlling the transmission dynamics of covid-19 Mathematical modelling of bacterial 486 meningitis transmission dynamics with control measures Co-dynamics of pneumonia and typhoid fever diseases with 490 cost effective optimal control analysis Optimal control strategies for dengue fever Cost-effectiveness analysis of optimal control strategies for breast cancer 494 treatment with ketogenic diet Modelling malaria dynamics with partial immunity 496 and protected travellers: optimal control and cost-effectiveness analysis
    keywords: analysis; control; covid-19; equation; model
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        item: #5111 of 7819
          id: cord-320267-n21jryi2
      author: AlShoaibi, Naeem A.
       title: Saudi Heart Rhythm Society Task Force on Management of Potential Arrhythmogenicity Associated with Pharmacotherapy for COVID-19
        date: 2020-09-20
       words: 3494
      flesch: 38
     summary: 41, 42 On-therapy QT assessment for high risk patients (QT ≥500 ms) should include a QT interval obtained 2-4 hours after the first dose, then again after 48 hours, then 96 hours. While no proven effective intervention exists, it is appropriate ethically to offer these experimental interventions to COVID-19 patients after taking into account all legal considerations.
    keywords: cardiac; covid-19; hydroxychloroquine; interval; patients; prolongation; risk
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        item: #5112 of 7819
          id: cord-320270-lduhhdld
      author: Obek, Can
       title: Management of prostate cancer patients during COVID-19 pandemic
        date: 2020-07-20
       words: 5554
      flesch: 42
     summary: Nonetheless, urologists practicing in hospitals treating COVID-19 patients may face situations when they have to perform urgent procedures on infected individuals. Visitors to COVID-19 patients need to be limited or preferably not allowed.
    keywords: adt; cancer; cov-2; covid-19; disease; ebrt; pandemic; patients; risk; sars; surgery; treatment
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        item: #5113 of 7819
          id: cord-320315-p85irulf
      author: Pulia, Michael S.
       title: COVID-19: An Emerging Threat to Antibiotic Stewardship in the Emergency Department
        date: 2020-08-07
       words: 2289
      flesch: 17
     summary: While these effects are speculative, due to a lack of detailed reporting on antibiotic treatment of COVID-19 patients in the ED, they share similarities with known challenges to ED antibiotic prescribing and can be mitigated by established stewardship interventions. The ED has unique, systemslevel barriers to quality improvement interventions that require customized approaches to antibiotic stewardship.
    keywords: covid-19; patients; prescribing; respiratory; stewardship
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        item: #5114 of 7819
          id: cord-320331-wtxja5i9
      author: Cabbab, Iris Louise N.
       title: Anti-Inflammatory Drugs and the Renin-Angiotensin-Aldosterone System: Current Knowledge and Potential Effects on Early SARS-CoV-2 Infection
        date: 2020-10-08
       words: 10078
      flesch: 32
     summary: Hence, the reduction in prostaglandin E 2 and I 2 syntheses is the main mechanism by which NSAIDs directly contribute to increased ACE2 expression, which can be utilized by SARS-CoV-2 (Fig. 2) . This may suggest the promotion of coronavirus replication secondary to immunosuppression, or of increased ACE2 expression secondary to osmotic diuresis, which we hypothesized earlier above (Fig. 4) .
    keywords: ace2; angiotensin; cells; coronavirus; corticosteroids; cov-2; covid-19; disease; drugs; expression; infection; patients; raas; review; sars; studies; study
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        item: #5115 of 7819
          id: cord-320344-z3l7dvyd
      author: Hotopf, Matthew
       title: The scope of mental health research during the COVID-19 pandemic and its aftermath
        date: 2020-06-04
       words: 2009
      flesch: 40
     summary: key: cord-320344-z3l7dvyd authors: Hotopf, Matthew; Bullmore, Ed; O'Connor, Rory C.; Holmes, Emily A. title: The scope of mental health research during the COVID-19 pandemic and its aftermath date: 2020-06-04 journal: The British journal of psychiatry : the journal of mental science DOI: 10.1192/bjp.2020.125 sha: doc_id: 320344 cord_uid: z3l7dvyd Second, it is critical that there are open, two-way channels between consumers (patients, public and policy makers) and producers of mental health research, so that scientists are oriented to the questions that matter most to the public, and policy-making is properly informed by the best evidence available.
    keywords: covid-19; health; need; pandemic; research
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        item: #5116 of 7819
          id: cord-320349-6hbuq0k7
      author: Zhou, Hua
       title: Development of early warning and rapid response system for patients with novel coronavirus pneumonia (COVID-19): A research protocol
        date: 2020-08-21
       words: 3504
      flesch: 37
     summary: After admission, EWRRS performs an initial assessment of COVID-19 patient disease severity based on past medical history, clinical symptoms, vital signs, and other auxiliary examinations. The intervention is implementation of EWRRS to detect early signs of clinical deterioration of COVID-19 patients, to provide timely and efficient treatment suggestions by the system.
    keywords: cases; clinical; covid-19; data; patients; symptoms; system; treatment; warning
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        item: #5117 of 7819
          id: cord-320350-zeeozmm9
      author: Nisoli, Enzo
       title: COVID-19 and Hartnup disease: an affair of intestinal amino acid malabsorption
        date: 2020-07-20
       words: 2507
      flesch: 38
     summary: We hypothesize that SARS-CoV-2 spike protein, binding to intestinal angiotensin-converting enzyme 2, negatively regulates the absorption of neutral amino acids, and this could explain not only the GI, but also systemic disturbances in COVID-19. In ACE2 knockout mice, luminal expression of B 0 AT1 in the intestine is completely lost [12] , demonstrating its fundamental role for the intestinal absorption of neutral amino acids (i.e., tryptophan, alanine, asparagine, glutamine, histidine, isoleucine, leucine, phenylalanine, serine, threonine, tyrosine, and valine)
    keywords: ace2; acid; amino; cov-2; covid-19; patients; sars
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        item: #5118 of 7819
          id: cord-320360-2qpcot6p
      author: Gumel, A. B.
       title: Will an imperfect vaccine curtail the COVID-19 pandemic in the U.S.?
        date: 2020-05-14
       words: 6543
      flesch: 42
     summary: In order to compute the community herd immunity thresholds for the US, New York state and Florida state, we compute the respective values of R 0 , using (3.8) with the baseline values of the community contact rates parameters, β a and β s , reduced by 30% (to account for the effect of the implementation of effective social-distancing measures [4] ). That is, we set β a = 0.8400, β s = 0.4971 for US, β a = 0.5648, β s = 0.3871 for New York state and β a = 0.7675, β s = 0.4621 for the state of Florida in Equation (3.8) to obtain the values of the basic reproduction number (R 0 ) for the US, New York state and the state of Florida.
    keywords: covid-19; florida; mask; new; state; vaccination; vaccine; york
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        item: #5119 of 7819
          id: cord-320361-lld2oib2
      author: Jackman, Deirdre
       title: Crisis and continuity: Rural health care students respond to the COVID-19 outbreak
        date: 2020-09-22
       words: 5756
      flesch: 44
     summary: key: cord-320361-lld2oib2 authors: Jackman, Deirdre; Konkin, Jill; Yonge, Olive; Myrick, Florence; Cockell, Jim title: Crisis and continuity: Rural health care students respond to the COVID-19 outbreak date: 2020-09-22 journal: Nurse Educ Pract DOI: 10.1016/j.nepr.2020.102892 sha: doc_id: 320361 cord_uid: lld2oib2 The COVID-19 outbreak in Winter (2020) has caused widespread disruption for health sciences students undergoing clinical placements—vital periods of experiential learning that cannot be substituted with distance alternatives. Technological connectivity and virtual gathering spaces have been used to support rural, clinical work for years, and the onsite assets impressed the students in their sophistication, Bradley (medicine) photographed the Telehealth station in his placement setting (Figure 8) , commenting, It's hard to [overstate] how much this has revolutionized rural health care in Canada… I will keep Telehealth in my mind throughout my practice, whether or not I work in a rural community, and remember how important a difference it can make.
    keywords: care; community; covid-19; health; medical; nursing; outbreak; r n; students
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        item: #5120 of 7819
          id: cord-320389-zgujsi9c
      author: Kalfaoglu, Bahire
       title: T-cell dysregulation in COVID-19
        date: 2020-11-07
       words: 3866
      flesch: 38
     summary: I interferon activity and inflammatory responses in severe COVID-19 patients Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal J o u r n a l P r e -p r o o f Pneumonia in SARS-CoV-Infected Mice Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19 Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19 T-Cell Hyperactivation and Paralysis in Severe COVID-19 Infection Revealed by Single-Cell Analysis CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86 Structure and function of the interleukin 2 receptor: affinity conversion model Controversies concerning thymus-derived regulatory T cells: fundamental issues and a new perspective Constitutive expression of IL-2Rbeta chain and its effects on IL-2-induced vascular leak syndrome Single-cell TCRseq: paired recovery of entire T-cell alpha and beta chain transcripts in T-cell receptors from single-cell RNAseq T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity Molecular Mechanisms RegulatinG Th1 Immune Responses Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients Single-cell RNA-seq and V(D)J profiling of immune cells in COVID-19 patients Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia Regulation of the Immune Response by the Aryl Hydrocarbon Receptor T follicular helper cell differentiation, function, and roles in disease Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 Comprehensive mapping of immune perturbations associated with severe COVID-19 RORC2: The master of human Th17 cell programming Humoral and circulating follicular helper T cell responses in recovered patients with COVID-19 Oxford Immunology Network Covid-19 Response, I.C. Investigators, Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19 Aberrant hyperactivation of cytotoxic T-cell as a potential determinant of COVID-19 severity Impaired Cytotoxic CD8+ T Cell Response in Elderly COVID-19 Patients Follicular CXCR5-expressing CD8+ T cells curtail chronic viral infection T cell receptor signalling in the control of regulatory T cell differentiation and function Regulatory T cells and immune tolerance Regulatory T Cells in Melanoma Revisited by a Computational Clustering of FOXP3+ T Cell Subpopulations Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor Regulatory T cells and immune tolerance in the intestine A timer for analyzing temporally dynamic changes in transcription during differentiation in vivo Control of regulatory T-cell differentiation and function by T-cell receptor signalling and Foxp3 transcription factor complexes Critical Role of TGF-β and IL-2 Receptor Signaling in Foxp3 Induction by an Inhibitor of DNA Methylation Control of Regulatory T Cell Development by the Transcription Factor Foxp3 From stability to dynamics: understanding molecular mechanisms of regulatory T cells through Foxp3 transcriptional dynamics The analysis of the long-term impact of SARS-CoV-2 on the cellular immune system in individuals recovering from COVID-19 reveals a profound NKT cell impairment Clinical and immunological features of severe and moderate coronavirus disease Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells The inhibition of IL-2/IL-2R gives rise to CD8+ T cell and lymphocyte decrease through JAK1-STAT5 in critical patients with COVID-19 pneumonia Coordination of early protective immunity to viral infection by regulatory T cells Role of regulatory T cells in coronavirus-induced acute encephalitis Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19 A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance Characterization of CD4+ T-cell-dendritic cell interactions during secondary antigen exposure in tolerance and priming A Single-Cell RNA Expression Map of Human Coronavirus Entry Factors CD4 + T cell responses to S-protein correlated with the concentration of the anti-SARS-CoV-2 IgG and IgA titres in convalescent patients [1] , showing the importance of the T-cell help for B-cell maturation in recovery from COVID-19.
    keywords: cells; covid-19; foxp3; patients; responses; type
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        item: #5121 of 7819
          id: cord-320426-fber0yzi
      author: Xia, Tianyi
       title: Small Solitary Ground-Glass Nodule on CT as an Initial Manifestation of Coronavirus Disease 2019 (COVID-19) Pneumonia
        date: 2020-04-06
       words: 1943
      flesch: 48
     summary: A confluent crazy-paving appearance presented in the same location as the nodule on chest CT images (Fig. 2B) . In addition, we recorded the evolution of chest CT findings in COVID-19 pneumonia.
    keywords: 2019; covid-19; ncov
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        item: #5122 of 7819
          id: cord-320447-nq9f1gmu
      author: Lins, Muriel
       title: Assessment of small pulmonary blood vessels in COVID-19 patients using HRCT
        date: 2020-07-25
       words: 2813
      flesch: 38
     summary: Compared to healthy volunteers, COVID-19 patients showed significant reduction in BV5 (pulmonary blood volume contained in blood vessels of <5 mm(2)) expressed as BV5/(Total pulmonary blood volume) (p<0.0001), and significant increases in BV5-10 and BV 10 (pulmonary blood volumes contained in vessels between 5 and 10 mm(2) and above 10 mm(2), respectively) (p<0.0001). Compared to healthy volunteers, COVID-19 patients showed significant reduction in BV5 (pulmonary blood volume contained in blood vessels of <5 mm 2 ) expressed as BV5/(Total pulmonary blood volume) (p<0.0001), and significant increases in BV5-10 and BV 10 (pulmonary blood volumes contained in vessels between 5 and 10 mm 2 and above 10 mm 2 , respectively) (p<0.0001).
    keywords: blood; covid-19; patients; vascular; vessels; volume
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        item: #5123 of 7819
          id: cord-320455-doup2bqq
      author: Werion, Alexis
       title: SARS-CoV-2 Causes a Specific Dysfunction of the Kidney Proximal Tubule
        date: 2020-08-10
       words: 2876
      flesch: 31
     summary: We recorded routine biological data obtained at admission, as well as the nadir lymphocyte count, and the peak values for highly sensitive C-reactive protein, lactate dehydrogenase and D-dimers The following antibodies were used: rabbit anti-human Gc-globulin (also known as VDBP, A0021, Dako); mouse anti-human ACE2 (AMAB91262, Sigma); rabbit anti-human ACE2 (AF933, R&D); rabbit anti-human AQP1 (ab2219, Millipore); sheep anti-LRP2 (gift from P. Verroust and R. Kozyraki, INSERM, Paris, France); rabbit anti-human UP1 (A0257, Dako); rabbit anti-human LMW proteins (A0126, Dako). Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention Clinical Characteristics of Coronavirus Disease 2019 in China Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus.
    keywords: ace2; coronavirus; covid-19; disease; dysfunction; human; kidney; patients; sars; tubule
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        item: #5124 of 7819
          id: cord-320460-7b8lqhl8
      author: Shapira, G.
       title: Ethnic differences in SERPINA1 allele frequencies may partially explain national differences in COVID-19 fatality rates
        date: 2020-08-26
       words: 1972
      flesch: 36
     summary: Until additional candidate alleles are found to better explain such national differences, the population variations in the allele frequencies of alpha-1 antitrypsin deficiency present a possible genetic explanation for the varying national COVID-19 burden. We applied estimated country-specific frequencies of alpha-1 antitrypsin deficiency [6] to analyze COVID-19 fatalities per thousand inhabitants vs. estimated alpha-1 antitrypsin deficiency in 67 countries (Fig. 2) .
    keywords: alpha-1; antitrypsin; covid-19; medrxiv; preprint
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        item: #5125 of 7819
          id: cord-320474-jyk7zphp
      author: Bonaventura, Aldo
       title: Targeting GM-CSF in COVID-19 Pneumonia: Rationale and Strategies
        date: 2020-07-03
       words: 5094
      flesch: 28
     summary: GM-CSF signals are mediated by the GM-CSF receptor (GM-CSF-R) consisting of a specific ligand-binding α-chain (GM CSF-Rα) and a signal-transducing β-chain (GM CSF-Rβ) ( Figure 1A) . The two-faced cytokine IL-6 in host defense and diseases Identification of predictive biomarkers for cytokine release syndrome after chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia Cytokine release syndrome: who is at risk and how to treat Toxicities of chimeric antigen receptor T cells: recognition and management The biology of GM-CSF: regulation of production and interaction with its receptor Pivotal roles of GM-CSF in autoimmunity and inflammation Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common beta-subunit Glucocorticoids promote apoptosis of proinflammatory monocytes by inhibiting ERK activity GM-CSF-dependent inflammatory pathways GM-CSF in inflammation Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation Myocarditis elicits dendritic cell and monocyte infiltration in the heart and self-antigen presentation by conventional type 2 dendritic cells GM-CSF-and IRF4-dependent signaling can regulate myeloid cell numbers and the macrophage phenotype during inflammation Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know Rheumatoid arthritis: opposing actions of haemopoietic growth factors and slow-acting anti-rheumatic drugs GM-CSF in inflammation and autoimmunity Colony-stimulating factors in inflammation and autoimmunity GM-CSF mediates autoimmunity by enhancing IL-6-dependent Th17 cell development and survival RORgammat drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation Colony stimulating factors and myeloid cell biology in health and disease Orally administered IL-6 induces elevated intestinal GM-CSF gene expression and splenic CFU-GM Inflammasomederived IL-1beta regulates the production of GM-CSF by CD4(+) T cells and gammadelta T cells IL-1beta and TNFalpha promote monocyte viability through the induction of GM-CSF expression by rheumatoid arthritis synovial fibroblasts G-CSF and IL-8 but not GM-CSF correlate with severity of pulmonary neutrophilia in acute respiratory distress syndrome Modulation of neutrophil apoptosis by granulocyte colony-stimulating factor and granulocyte/macrophage colony-stimulating factor during the course of acute respiratory distress syndrome The pathogenic involvement of neutrophils in acute respiratory distress syndrome and transfusion-related acute lung injury Novel findings in neutrophil biology and their impact on cardiovascular disease Dual role of GM-CSF as a pro-inflammatory and a regulatory cytokine: implications for immune therapy Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small-cell lung cancer Fc receptor-mediated phagocytosis makes a significant contribution to clearance of influenza virus infections Alveolar macrophages in the resolution of inflammation, tissue repair, and tolerance to infection Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice Alveolar macrophages are indispensable for controlling influenza viruses in lungs of pigs GM-CSF in the lung protects against lethal influenza infection Delivery of GM-CSF to protect against influenza pneumonia Identification of a nerve-associated, lung-resident interstitial macrophage subset with distinct localization and immunoregulatory properties Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice A dual role for the immune response in a mouse model of inflammation-associated lung cancer Pulmonary alveolar proteinosis in adults: pathophysiology and clinical approach Hereditary pulmonary alveolar proteinosis: pathogenesis, presentation, diagnosis, and therapy Aberrant pathogenic GM-CSF + T cells and inflammatory CD14 + CD16 + monocytes in severe pulmonary syndrome patients of a new coronavirus.
    keywords: cells; covid-19; csf; cytokine; factor; il-6; lung; macrophages; mavrilimumab; patients
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        item: #5126 of 7819
          id: cord-320499-76o2zj0v
      author: Davoodi, Lotfollah
       title: Hydroxychloroquine-induced Stevens–Johnson syndrome in COVID-19: a rare case report
        date: 2020-06-25
       words: 1387
      flesch: 46
     summary: One of the drugs prescribed to improve the condition of COVID-19 patients is the antimalarial hydroxychloroquine (HCQ), which recently reported as a supportive drug for shortening the duration of COVID-19 symptoms, reducing inflammatory reactions to infection, impairing the exacerbation of pneumonia and boosting lung imaging findings [3] . Like all medications, HCQ has side effects and may occur in COVID-19 patients.
    keywords: covid-19; drug; hcq; rash
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        item: #5127 of 7819
          id: cord-320509-3a40djjm
      author: Benke, Christoph
       title: Lockdown, quarantine measures, and social distancing: Associations with depression, anxiety and distress at the beginning of the COVID-19 pandemic among adults from Germany
        date: 2020-09-18
       words: 4082
      flesch: 36
     summary: In addition to sociodemographic and COVID-19-related variables (see Table 1 for an overview), we assessed the following variables related to implemented public health measures: Perceived changes in life due to public health measures: Participants were asked to rate how much their everyday life had changed due to governmental measures that were taken to contain COVID-19 spreading on a 9-point Likert-scale (ranging from not at all to very strong) and whether they perceived these changes as positive, neutral, or negative. To prevent the spread of Sars-CoV-2, governments worldwide have implemented different forms of public health measures ranging from physical distancing recommendations to stay-at-home orders, which have disrupted individuals’ everyday life tremendously.
    keywords: covid-19; health; home; measures; order; stay
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        item: #5128 of 7819
          id: cord-320514-nd6c1xjn
      author: Ari, Selma
       title: Elevated eosinophil count is related with lower anti-factor Xa activity in COVID-19 patients
        date: 2020-10-08
       words: 3338
      flesch: 42
     summary: Anti-factor Xa activity was higher in COVID-19 negative patients than in group 1 patients (COVID-19 positive patients) however eosinophil level was similar in these two groups; Anti-factor Xa activity (mean ± SD); COVID-19 negative patients: 0.78 ± 0.53 vs group 1 patients: 0.18 ± 0.06, p = 0.001, eosinophil percent (%) (mean ± SD); COVID-19 negative patients: 2.40 ± 1.28 vs group 1 patients: 2.96 ± 2.55, p = 0.54, eosinophil count (mean ± SD); COVID-19 negative patients: 217.77 ± 151.14 vs group 1 patients: 168.42 ± 147.25, p = 0.45. This study aimed to evaluate the factors influencing anti-factor Xa activity in COVID-19 patients receiving low molecular weight heparin (LMWH).
    keywords: activity; anti; covid-19; eosinophil; factor; patients
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        item: #5129 of 7819
          id: cord-320530-5xltmc65
      author: Bozorgmehr, Kayvan
       title: Power of and power over COVID-19 response guidelines
        date: 2020-10-05
       words: 631
      flesch: 42
     summary: The Competence Network Public Health COVID-19 raised ethical, legal, and epidemiological concerns about questionable benefits for infection control and high psychosocial burden for refugees, and it urged for national guidelines on prevention and management of SARS-CoV-2 in refugee centres. This effectively offers a legal loophole to avoid enforcement of physical distancing in refugee centres to the same extent as for the general population, despite court judgements suspending the obligation of individual refugees to live in crowded centres if physical distancing is not possible.
    keywords: covid-19; health
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        item: #5130 of 7819
          id: cord-320535-fo4lzcav
      author: Geyer, Howard L.
       title: Movement Disorders in COVID-19: Whither Art Thou?
        date: 2020-08-12
       words: 1665
      flesch: 29
     summary: (Another tantalizing finding of that study is that the substantia nigra of these mice exhibited increased mRNA expression of pro-inflammatory markers including interleukin-6, a cytokine that is elevated in COVID-19 patients and correlates with disease severity [16] ). What might account for the dearth of expected movement disorders in COVID-19 patients?
    keywords: covid-19; disorders; movement; patients; sars
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        item: #5131 of 7819
          id: cord-320572-94fvtj4a
      author: Wendel Garcia, Pedro David
       title: Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort
        date: 2020-07-06
       words: 5418
      flesch: 38
     summary: Following the critical developments in ICUs in regions experiencing early inception of the pandemic, the European-based, international RIsk Stratification in COVID-19 patients in the Intensive Care Unit (RISC-19-ICU) registry was created to provide near real-time assessment of patients developing critical illness due to COVID-19. Following the critical spread of the disease in China, Italy and Spain, on March 13, 2020 the European-based RIsk Stratification in COVID-19 patients in the ICU (RISC-19-ICU) registry was launched to allow nearreal time assessment of the main clinical characteristics of critically ill patients during the emerging COVID-19 pandemic.
    keywords: acute; analysis; care; covid-19; data; disease; icu; model; mortality; patients; registry; study; survivors
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        item: #5132 of 7819
          id: cord-320603-pus087p8
      author: Ning, Xianjun
       title: The mental health of neurological doctors and nurses in Hunan Province, China during the initial stages of the COVID-19 outbreak
        date: 2020-09-05
       words: 4427
      flesch: 41
     summary: medical health workers Currently, no studies have focused on the psychological impact on a particular group, such as neurological medical workers.
    keywords: anxiety; coronavirus; covid-19; depression; health; nurses; study; workers
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        item: #5133 of 7819
          id: cord-320614-5qph7yen
      author: Patel, Aniruddh P.
       title: Race, socioeconomic deprivation, and hospitalization for COVID-19 in English participants of a national biobank
        date: 2020-07-06
       words: 1286
      flesch: 30
     summary: COVID-19 hospitalization was noted in 32 of 7714 (0.4%) To understand the relationship between socioeconomic status and COVID-19 hospitalization, individuals were stratified at enrollment into deciles of the Townsend Deprivation Index, a previously validated Fig. 1 COVID-19 hospitalization rates by race and geographic region, Townsend Deprivation Index, and household income.
    keywords: covid-19; deprivation; hospitalization; participants
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        item: #5134 of 7819
          id: cord-320625-ggx33mpt
      author: Lipworth, Brian
       title: Use of inhaled corticosteroids in asthma and coronavirus disease 2019: Keep calm and carry on
        date: 2020-07-01
       words: 1164
      flesch: 34
     summary: A Canadian cohort study of asthma patients found that current exposure to ICS was accompanied by a 45% relative increase in risk of bacterial pneumonia. In contrast, a study of H1N1 influenza A infection among 1520 hospitalized patients in United Kingdom found that those with asthma were 49% less likely to require intensive care support or were less likely to die than those without asthma, which was attributed to ICS use.
    keywords: asthma; covid-19; ics; patients
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        item: #5135 of 7819
          id: cord-320632-369kax2m
      author: Song, Yang
       title: COVID-19 Treatment: Close to a Cure? – A Rapid Review of Pharmacotherapies for the Novel Coronavirus
        date: 2020-07-04
       words: 5670
      flesch: 42
     summary: In another prospective observational study, IVIG was used in SARS patients with severe leukopenia or thrombocytopenia, and it appeared to be effective for controlling cytopenia by increasing leukocyte and platelet counts. In COVID-19 patients with ARDS, treatment with steroids is associated with decreased risk of death compared to the patients who did not receive steroids (46% vs 61.8%)
    keywords: clinical; coronavirus; covid-19; disease; group; lpv; patients; remdesivir; ribavirin; sars; study; syndrome; therapy; treatment
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        item: #5136 of 7819
          id: cord-320636-mvtux07x
      author: Pullano, G.
       title: Underdetection of COVID-19 cases in France in the exit phase following lockdown
        date: 2020-08-12
       words: 5262
      flesch: 43
     summary: key: cord-320636-mvtux07x authors: Pullano, G.; Di Domenico, L.; Sabbatini, C. E.; Valdano, E.; Turbelin, C.; Debin, M.; Guerrisi, C.; Kengne-Kuetche, C.; Souty, C.; Hanslik, T.; Blanchon, T.; Boe�lle, P.-Y.; Figoni, J.; Vaux, S.; Campese, C.; Bernard-Stoecklin, S.; Colizza, V. title: Underdetection of COVID-19 cases in France in the exit phase following lockdown date: 2020-08-12 journal: nan DOI: 10.1101/2020.08.10.20171744 sha: doc_id: 320636 cord_uid: mvtux07x A novel testing policy was implemented in May in France to systematically screen potential COVID-19 infections and suppress local outbreaks while lifting lockdown restrictions. This may potentially result in substantial underestimates of the real number of COVID-19 cases in the country.
    keywords: cases; covid-19; data; france; lockdown; onset; preprint; surveillance; symptoms; testing; time
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        item: #5137 of 7819
          id: cord-320640-5m6sqwq8
      author: Kumar, Harender
       title: COVID-19 Creating another problem? Sustainable solution for PPE disposal through LCA approach
        date: 2020-10-09
       words: 4518
      flesch: 38
     summary: Thus, our present study on Life Cycle Assessment of PPEs for disposal of infectious PPE waste becomes very vital for environmentally sound management of PPE waste. The results from the research can be used for decision making to plan future strategies for environmentally sound management of COVID-19 infected PPE waste.
    keywords: covid-19; disposal; health; impact; life; management; ppe; ppes; study; use; waste
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        item: #5138 of 7819
          id: cord-320645-wu0sdbrk
      author: Hakim, Radwan
       title: COVID-19 et SCA ST+
        date: 2020-10-01
       words: 2411
      flesch: 54
     summary: En France où l'angioplastie primaire est, de loin, le mode de revascularisation le plus utilisé dans l'infarctus, l'épidémie n'a pas modifié cette stratégie avec un taux de recours à la thrombolyse qui est resté exceptionnel (2 %). L’allongement des délais et du temps total d’ischémie a conduit à une surmortalité, notamment dans les régions les plus affectées par l’épidémie.
    keywords: covid-19; dans; des; est; les; patients; une
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        item: #5139 of 7819
          id: cord-320646-xk77u4g0
      author: Zumla, Alimuddin
       title: The explosive epidemic outbreak of novel coronavirus disease 2019 (COVID-19) and the persistent threat of respiratory tract infectious diseases to global health security
        date: 2020-04-09
       words: 2407
      flesch: 43
     summary: key: cord-320646-xk77u4g0 authors: Zumla, Alimuddin; Niederman, Michael S. title: The explosive epidemic outbreak of novel coronavirus disease 2019 (COVID-19) and the persistent threat of respiratory tract infectious diseases to global health security date: 2020-04-09 journal: Curr Opin Pulm Med DOI: 10.1097/mcp.0000000000000676 sha: doc_id: 320646 cord_uid: xk77u4g0 nan Respiratory tract infections remain the top cause of morbidity and mortality from infectious diseases worldwide [1] . Global research on coronavirus disease (COVID-19 Reducing mortality from 2019-nCoV: host-directed therapies should be an option Transmission of respiratory Tract infections at mass gathering events Update in adult community-acquired pneumonia: key points from the new ATS/IDSA 2019 Guideline Viral respiratory infections: a cause of CAP, or a predisposing factor Martin-Loesches I. Influenza management with new therapies Pneumococcal virulence factors New biomarkers for respiratory infections Advances in molecular diagnostic tests for pneumonia Strategies for prediction of drug-resistant pathogens and empiric antibiotic selection in community-acquired pneumonia Beyond antibiotics for pulmonary nontuberculous mycobacterial disease Sir Alimuddin Zumla is a co-PI of the Pan-African Network on Emerging and Re-Emerging Infections (PANDORA-ID-NET; https://www.pandora-id.net/) funded by the European and Developing Countries Clinical Trials Partnership the EU Horizon 2020 Framework Programme for Research and Innovation.
    keywords: china; coronavirus; covid-19; novel; patients; respiratory; sars
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        item: #5140 of 7819
          id: cord-320647-a3wf2sl1
      author: Liu, Qi
       title: Effect of a bundle of intervention strategies for the control of COVID-19 in Henan, a neighboring province of Wuhan, China
        date: 2020-06-16
       words: 1792
      flesch: 51
     summary: The peak of daily increased cases was 109 cases. daily increased cases was 109 cases.
    keywords: cases; covid-19; province; strategies
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        item: #5141 of 7819
          id: cord-320656-5gu6ejul
      author: Moran, Joseph V
       title: Post-Extubation Stridor Complicating COVID-19-Associated Acute Respiratory Distress Syndrome: A Case Series
        date: 2020-09-16
       words: 1574
      flesch: 36
     summary: It is not yet clear if this is also true for COVID-19 patients who undergo proning and further analysis is needed to determine if proning is also a risk factor for post-extubation stridor in this population. Since this assessment may not provide an accurate evaluation of the presence of laryngeal edema or predict the occurrence of post-extubation stridor, some clinicians may prefer to avoid the cuff leak test in COVID-19 patients altogether to reduce the risk of aerosolization of the virus.
    keywords: extubation; patients; stridor
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        item: #5142 of 7819
          id: cord-320661-p7tyfqyu
      author: Branson, Rich
       title: The US Strategic National Stockpile (SNS) Ventilators in COVID-19: A Comparison of Functionality and Analysis regarding the Emergency Purchase of 200,000 devices.
        date: 2020-09-21
       words: 2536
      flesch: 32
     summary: Intended areas of use: Mechanical ventilators in US acute care hospitals Emergency response planning in hospitals Emergency Use Authorization for Ventilators 2020; Enforcement Policy for Ventilators and Accessories and Other Respiratory Devices During the Coronavirus Disease 2019 (COVID-2019) Public Health Emergency: Guidance for Industry and Food and Drug Administration Staff Becoming 'King of Ventilators' may result in unexpected glut Advances in mechanical ventilation Basic invasive mechanical ventilation Invasive Mechanical Ventilation Physiologic Basis of Mechanical Ventilation Management of COVID-19 Respiratory Distress COVID-19 pneumonia: different respiratory treatments for different phenotypes? Surge capacity logistics: care of the critically ill and injured during pandemics and disasters: CHEST consensus statement Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome Clinicopathologic and Immunohistochemical Findings from Autopsy of Patient with COVID-19 COVID-19 Autopsies Post-mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State Covid-19 in Critically Ill Patients in the Seattle Region date: 2020-09-21 journal: Chest DOI: 10.1016/j.chest.2020.09.085 sha: doc_id: 320661 cord_uid: p7tyfqyu Background Early in the COVID-19 pandemic, there was serious concern that the United States (US) would encounter a short fall of mechanical ventilators.
    keywords: covid-19; emergency; patients; pressure; sns; use; ventilation; ventilators
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        item: #5143 of 7819
          id: cord-320663-xypg6evo
      author: Market, Marisa
       title: Flattening the COVID-19 Curve With Natural Killer Cell Based Immunotherapies
        date: 2020-06-23
       words: 14058
      flesch: 29
     summary: A natural killer cell receptor for HLA-B allotypes Molecular clones of the p58 NK cell receptor reveal immunoglobulinrelated molecules with diversity in both the extra-and intracellular domains HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C Mouse CD94/NKG2A is a natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b) TLR-mediated activation of NK cells and their role in bacterial/viral immune responses in mammals Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells Ly49H signaling through DAP10 is essential for optimal natural killer cell responses to mouse cytomegalovirus infection Human NK cells and herpesviruses: mechanisms of recognition, response and adaptation Cytokine regulation of natural killer cell effector functions Coordinated and distinct roles for IFN-αβ, IL-12, and IL-15 regulation of NK cell responses to viral infection Developmental and functional control of natural killer cells by cytokines. Despite their vital role in viral infection, the contribution of NK cells in fighting SARS-CoV-2 has not yet been directly investigated.
    keywords: acute; cancer; cells; coronavirus; cov-2; covid-19; cytokine; disease; human; ifn; immune; infection; killer; levels; mers; nk cells; patients; respiratory; response; role; sars; studies; syndrome; therapy; type
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        item: #5144 of 7819
          id: cord-320673-4guarm0k
      author: Lopera, E.
       title: Lack of association between genetic variants at ACE2 and TMPRSS2 genes involved in SARS-CoV-2 infection and human quantitative phenotypes
        date: 2020-04-25
       words: 4181
      flesch: 39
     summary: key: cord-320673-4guarm0k authors: Lopera, E.; van der Graaf, A.; Lanting, P.; van der Geest, M.; Lifelines Cohort Study,; Fu, J.; Swertz, M.; Franke, L.; Wijmenga, C.; Deelen, P.; Zhernakova, A.; Sanna, S. title: Lack of association between genetic variants at ACE2 and TMPRSS2 genes involved in SARS-CoV-2 infection and human quantitative phenotypes date: 2020-04-25 journal: nan DOI: 10.1101/2020.04.22.20074963 sha: doc_id: 320673 cord_uid: 4guarm0k Coronavirus disease 2019 (COVID-19) shows a wide variation in expression and severity of symptoms, from very mild or no symptomes, to flu-like symptoms, and in more severe cases, to pneumonia, acute respiratory distress syndrome and even death. While large-scale genetic studies of COVID-19 patients are being assembled, such as those coordinated by the COVID host genetics consortium (https://www.covid19hg.com/), it is worthwhile to evaluate the effects of genetic variants in genes involved in SARS-CoV-2 infection on human phenotypes, including quantitative traits, taking advantage of already existing cohorts.
    keywords: ace2; association; cohort; covid-19; phenotypes; population; sars; use; variants
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        item: #5145 of 7819
          id: cord-320681-b3ui95vx
      author: Zhang, Rui
       title: COVID-19: Melatonin as a potential adjuvant treatment
        date: 2020-06-01
       words: 4147
      flesch: 32
     summary: Melatonin exerts anti-inflammatory effects through various pathways. TNF-α, IL-1β, IL-6, and IL-8, and an elevation in the level of anti-inflammatory cytokine IL-10
    keywords: acute; ali; anti; covid-19; inflammation; injury; lung; melatonin; patients; sars
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        item: #5146 of 7819
          id: cord-320689-upxsdgqd
      author: Shetty, Sameep S.
       title: Vicissitudes in oncological care during COVID19
        date: 2020-05-11
       words: 730
      flesch: 22
     summary: Industrial Marketing Management Temporal dynamics in viral shedding and transmissibility of COVID-19 Chest CT for Typical 2019-nCoV Pneumonia: Relationship to Negative RT-PCTesting Covid19: minimising risk to healthcare workers during aerosol producing respiratory therapy using an innovative constant flow canopy Meta-analysis of average and variability of time to extubation comparing isoflurane with desflurane or isoflurane with sevoflurane Conversion of operating theatre from positive to negative pressure environment Temperature-controlled airflow ventilation in operating rooms compared with laminar airflow and turbulent mixed airflow Endoscopic Skull Base and Transoral Surgery During the COVID -19 Pandemic: Minimizing Droplet Spread with a Negative-Pressure Otolaryngology Viral Isolation Drape ( NOVID ) Evaluation of a pulsed xenon ultraviolet disinfection system for reduction of healthcare-associated pathogens in hospital rooms Combating COVID-19-The role of robotics in managing public health and infectious diseases Robot assisted surgery during the COVID-19 pandemic, especially for gynecological cancer: a statement of the Society of European Robotic Gynaecological Surgery (SERGS) COVID-19 can also be a catalyst for integrating robots and Artificial intelligence into the health care system and minimize the exposure risk to health care workers.
    keywords: cancer; care; covid-19
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        item: #5147 of 7819
          id: cord-320740-npoje09j
      author: Musa, Arif
       title: Remdesivir for the Treatment of COVID-19: A Systematic Review of the Literature
        date: 2020-05-20
       words: 2300
      flesch: 48
     summary: The authors suggested that additional clinical studies were needed to complete the safety and efficacy profiles of the anti-viral drug. Studies were excluded for meeting any of the following criteria: non-human study (n = 3); review or metaanalysis (n = 15); not including SARS-CoV-2 (n = 16); or multiple criteria met (n = 23).
    keywords: covid-19; remdesivir; treatment
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        item: #5148 of 7819
          id: cord-320755-0zpnwl2k
      author: Mateen, Farrah J.
       title: Impact of COVID-19 on U.S. and Canadian neurologists’ therapeutic approach to multiple sclerosis: a survey of knowledge, attitudes, and practices
        date: 2020-07-07
       words: 4240
      flesch: 47
     summary: Larger efforts are ongoing, but a synthesized report on MS patients and their outcomes was not yet published when our study commenced. The overall objectives of this study were threefold: (1) to report the range of impacts of COVID-19 on neuroimmunologists' practice across the USA and Canada; (2) to probe the MS DMT prescribing decisions and planning of neuroimmunologists in the setting of a viral pandemic; and (3) determine the unmet needs and sources of uncertainty that dominate the care of MS patients.
    keywords: covid-19; dmts; neurologists; patients; respondents; risk; study; survey
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        item: #5149 of 7819
          id: cord-320773-zisujjsx
      author: Sabat, Iryna
       title: United but divided: policy responses and people's perceptions in the EU during the COVID-19 outbreak
        date: 2020-06-22
       words: 5644
      flesch: 48
     summary: Explaining the need for and the advantages of such intrusive policies through trusted means of communication, while addressing people's concerns explicitly and being open about the risks of using such policy measures may help raise the support and compliance in society to a sufficient degree. Citizens were overall satisfied with their government's response to the pandemic; however, the extent of approval differed across countries and policy measures.
    keywords: countries; covid-19; government; health; italy; measures; people; policies; public; trust
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        item: #5150 of 7819
          id: cord-320785-42p8292o
      author: Lobo, Andréa de Paula
       title: COVID-19 epidemic in Brazil: where we at?
        date: 2020-06-16
       words: 682
      flesch: 60
     summary: Joinpoint regression models were applied to identify points of inflection in COVID-19 trends, considering the days since the 50th confirmed case as time unit. Method ecological time-series based on cumulative confirmed cases of COVID-19 from March 11 to May 12.
    keywords: cases; covid-19; fus
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        item: #5151 of 7819
          id: cord-320811-9sm7iz5x
      author: Harkin, Denis W.
       title: Ethics for surgeons during the COVID-19 pandemic, review article
        date: 2020-06-08
       words: 3530
      flesch: 38
     summary: However, it is vital that infection prevention and control measures are robust, patients risk stratified by COVID-19 testing and staff protected with personalprotective equipment (PPE) and environmental shielding, otherwise isolated or sick staff will further deplete surgical care. Reference Guide to Consent for Examination or Treatment Interventions to Improve Patient Comprehension in Informed Consent for Medical and Surgical Procedures: An Updated Systematic Review Implications for the use of telehealth in surgical patients during the COVID-19 pandemic World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects Economic Recovery After the COVID-19 Pandemic: Resuming Elective Orthopedic Surgery and Total Joint Arthroplasty Medical error in the care of the unrepresented: disclosure and apology for a vulnerable patient population � The Covid-19 pandemic is a devastating global healthcare emergency with seismic impact on how modern surgical services function.� Surgeons worry, that whilst healthcare-resources are directed against the pandemic, double effect may predict these benevolent public health efforts will cause unintended maleficent effects through delays to surgical treatment.� The practice of surgery is distinguished by good judgement in the face of uncertainty, we must strive to act ethically, do the right thing, advocate for our patients, and be honest in the face of uncertainty.
    keywords: care; covid-19; healthcare; medical; pandemic; patients; surgeons
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        item: #5152 of 7819
          id: cord-320815-p9oh54nt
      author: Gentile, Pietro
       title: Research progress on Mesenchymal Stem Cells (MSCs), Adipose-Derived Mesenchymal Stem Cells (AD-MSCs), Drugs, and Vaccines in Inhibiting COVID-19 Disease
        date: 2020-10-01
       words: 4727
      flesch: 39
     summary: This article reviewed, at the current day, the research progress on stem cell therapy in COVID-19 patients, and in particular focused on the clinical research status of MSCs and AD-MSCs biotechnology, reporting also an update on drugs and vaccines, so as to provide a reference for frontline clinical and scientific researchers. These effects were confirmed by the increased peripheral lymphocytes amount, the decline in the C-reactive protein, and waning of over-activated cytokine-secreting immune cells (CXCR3+CD4+ T cells, CXCR3+CD8+ T cells, and CXCR3+ NK cells) into the blood of COVID-19 patients, by mean 4.5 days later the MSCs intravenous infusion
    keywords: cells; covid-19; disease; drugs; mesenchymal; mscs; patients; sars; stem; studies; therapy
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        item: #5153 of 7819
          id: cord-320822-etibcspx
      author: Wright, Franklin L.
       title: Fibrinolysis Shutdown Correlates to Thromboembolic Events in Severe COVID-19 Infection
        date: 2020-05-15
       words: 2421
      flesch: 24
     summary: Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Procoagulant activity during viral infections Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Serum D-dimer changes and prognostic implication in 2009 novel influenza A(H1N1) Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Hypercoagulability of COVID-19 patients in Intensive Care Unit. Patients with fibrinolysis shutdown had a 40% rate of VTE compared to 5% in patients without shutdown (p=0.013).
    keywords: coagulation; covid-19; fibrinolysis; patients; shutdown; teg
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        item: #5154 of 7819
          id: cord-320823-a1fq6mno
      author: Moula, Amalia Ioanna
       title: Quantification of Death Risk in Relation to Sex, Pre-Existing Cardiovascular Diseases and Risk Factors in COVID-19 Patients: Let’s Take Stock and See Where We Are
        date: 2020-08-19
       words: 4140
      flesch: 47
     summary: Both ACE2 receptors and CD26 are targets for coronaviruses, and their overexpression in older patients might mediate the increased fatality rate in COVID-19 patients [40] . Patients with pre-existing cerebrovascular disease tend to die 1.76-fold more than patients without cerebrovascular disease, suggesting that cerebrovascular disease is a strong predictor of death ( Figure 4E , RR: 1.76
    keywords: analysis; cad; covid-19; cvd; disease; mortality; patients; risk
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        item: #5155 of 7819
          id: cord-320831-owfnttqr
      author: Klimek, Ludger
       title: Allergen immunotherapy in the current COVID-19 pandemic: A position paper of AeDA, ARIA, EAACI, DGAKI and GPA: Position paper of the German ARIA Group(A) in cooperation with the Austrian ARIA Group(B), the Swiss ARIA Group(C), German Society for Applied Allergology (AEDA)(D), German Society for Allergology and Clinical Immunology (DGAKI)(E), Society for Pediatric Allergology (GPA)(F) in cooperation with AG Clinical Immunology, Allergology and Environmental Medicine of the DGHNO-KHC(G) and the European Academy of Allergy and Clinical Immunology (EAACI)(H)
        date: 2020-05-28
       words: 3690
      flesch: 36
     summary: AIT aims at inducing allergen-specific immune tolerance in allergic patients by utilizing effects on several immune mechanisms (Table 1) , including T cells, B cells, innate lymphoid cells (ILCs), and effector cells, such as eosinophils, mast cells, and basophils The start of AIT in allergic patients without known SARS-CoV-2 exposure who do not show COVID-19 symptoms, but whose current SARS-CoV-2 infection and immune status are unknown, requires a thorough examination for signs of SARS-CoV-2 infection during the indication for AIT, and the same examination should be repeated at the start of AIT.
    keywords: ait; allergen; allergy; cells; covid-19; disease; immunotherapy; infection; patients; risk; sars; symptoms
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        item: #5156 of 7819
          id: cord-320860-qt84oicg
      author: Zhang, Aining
       title: Meta-Analysis of coagulation parameters associated with disease severity and poor prognosis of COVID-19
        date: 2020-09-15
       words: 2363
      flesch: 37
     summary: The unique characteristics of COVID-19 coagulopathy Development of a critical appraisal tool to assess the quality of cross-sectional studies (AXIS) Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better Diagnostic utility of clinical laboratory data determinations for patients with the severe COVID-19 Correlation Between Relative Nasopharyngeal Virus RNA Load and Lymphocyte Count Disease Severity in Patients with COVID Clinical features and treatment of COVID-19 patients in northeast Chongqing Suppressed T cell-mediated immunity in patients with COVID-19: a clinical retrospective study in Wuhan Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Epidemiological, clinical and virological characteristics of 74 cases of coronavirus Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Prominent changes in blood coagulation of patients with SARS-CoV-2 infection Procalcitonin in patients with severe coronavirus disease 2019 (COVID-19): A meta-analysis PPIs and Beyond: A Framework for Managing Anticoagulation-Related Gastrointestinal Bleeding in the Era of COVID-19 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 Prevention and Treatment of Venous Thromboembolism Associated with Coronavirus Disease 2019 Conclusions Our data support the notion that coagulopathy could be considered as a risk factor for disease severity and mortality of COVID-19, which may help clinicians to identify the incidence of poor outcomes in COVID-19 patients.
    keywords: coagulation; coronavirus; covid-19; disease; patients; studies
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        item: #5157 of 7819
          id: cord-320864-k9zksbyt
      author: Remes-Troche, J. M.
       title: Recommendations for the reopening and activity resumption of the neurogastroenterology units in the face of the COVID-19 pandemic. Position of the Sociedad Latinoamericana de Neurogastroenterología
        date: 2020-11-01
       words: 4674
      flesch: 40
     summary: but due to the fact that the epidemiologic behavior, protective equipment avail-ability, serologic diagnostic test performance capacity for corroborating immunity, and socioeconomic context are different throughout Latin America, a group of experts that are members of the Sociedad Latinoamericana de Neurogastroenterología (SLNG) had a virtual meeting to formulate a consensus document with recommendations for the performance of gastrointestinal motility tests. According to the International Anorectal Physiology Working Group (IAPWG) and the London classification, the conventional indications for performing anorectal function tests (primarily anorectal manometry [ARM]) 17 are: 1) constipation and/or defecation disorder symptom evaluation, 2) fecal incontinence (FI) evaluation, 3) painful anorectal disorder evaluation, 4) preoperative and postoperative evaluation of ileorectal anastomoses, rectopexy, fistulotomies, etc., and 5) evaluation of obstetric trauma.
    keywords: case; country; covid-19; infection; motility; pandemic; patients; performance; recommendations; risk; tests; use
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        item: #5158 of 7819
          id: cord-320877-1i0hzfjk
      author: KIYKAÇ ALTINBAŞ, Şadıman
       title: Gynecological laparoscopic surgery in the shade of COVID-19 pandemic
        date: 2020-06-23
       words: 2815
      flesch: 40
     summary: Since January, in the three months, changing in the actual policies and getting out of the routine, the decision of the route of surgery either by traditional open surgery or laparoscopic surgery is being discussed and stated regarding surgical safety concerns [2] . Recently, international societies have made recommendations based on published reasonable data and expert opinion about laparoscopic surgery during coronavirus outbreak.
    keywords: covid-19; laparoscopy; pandemic; patients; surgery; transmission; use
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        item: #5159 of 7819
          id: cord-320888-mn7btxy2
      author: Ameh, C. A.
       title: Reproductive Maternal and Newborn Health providers assessment of facility preparedness and its Determinants during the COVID-19 pandemic in Lagos, Nigeria
        date: 2020-09-25
       words: 5975
      flesch: 38
     summary: We performed an ordinal regression analysis with health care worker perception of COVID-19 health facility preparedness (1-not prepared to 5-extremely well prepared) as the outcome or dependent variable and independent or predictor variables. Other studies assessing preparedness to manage COVID-19 assessed health workers knowledge, attitude and practice, but did not explore the complex interaction between fear, anxiety, stress, support systems and health facility preparedness.
    keywords: availability; covid-19; facilities; health; medrxiv; preparedness; preprint; rmnh; services; work
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        item: #5160 of 7819
          id: cord-320892-dcfi5u04
      author: Kaidi, Austin C.
       title: Timing and Tips for Total Hip Arthroplasty in a Critically Ill COVID-19 Patient with a Femoral Neck Fracture: A Case Report
        date: 2020-07-14
       words: 1297
      flesch: 32
     summary: A Meta-Analysis and Meta-Regression 228 of over 190,000 Patients Early 231 and ultra-early surgery in hip fracture patients improves survival Early Surgery Confers 1-Year Mortality Benefit 234 in Hip-Fracture Patients Hip Fracture 237 Covid-19 in Critically Ill Patients in the 239 Seattle Region -Case Series Characteristics and Early Prognosis of 241 COVID-19 Infection in Fracture Patients Novel Coronavirus Infection in Clinical course and risk factors for mortality of adult inpatients 249 with COVID-19 in Wuhan, China: a retrospective cohort study The effect of intravertebral anesthesia on bone cement 252 implantation syndrome in aged patients A single-center 5-year retrospective study Hypercoagulability Syndrome in Patients With Coronavirus Disease Critically Ill Expert consensus on management principles of 259 orthopedic emergency in the epidemic of coronavirus disease 2019 Preventive strategy for the clinical treatment of hip fractures in 262 the elderly during the COVID-19 outbreak: Wuhan&#x2019;s experience Understanding Bone Cement Implantation Syndrome Postoperative 276 30-day complications after cemented/hybrid versus cementless total hip arthroplasty in 277 osteoarthritis patients > 70 years: A multicenter study from the Lundbeck Foundation 278 Centre for Fast-track Hip and Knee replacement database and the Danish Hip Arthroplasty 279 Diagnosis and management of bone cement 281 implantation syndrome: Case report and brief review Complications of cemented long-stem hip 284 arthroplasties in metastatic bone disease A 70-year-old man with intraoperative hypoxia and 287 hypotension during total hip replacement Total Hip Arthroplasty or Hemiarthroplasty 290 for Hip Fracture However, the optimal timing of surgery in patients with novel coronavirus disease 2019 (COVID-19) infection remains unknown.
    keywords: covid-19; fracture; hip; patient
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        item: #5161 of 7819
          id: cord-320895-y6pzrbdi
      author: Arab-Zozani, Morteza
       title: COVID-19 in Iran: the Good, the Bad, and the Ugly Strategies for Preparedness – A Report From the Field
        date: 2020-09-27
       words: 1822
      flesch: 43
     summary: key: cord-320895-y6pzrbdi authors: Arab-Zozani, Morteza; Ghoddoosi-Nejad, Djavad title: COVID-19 in Iran: the Good, the Bad, and the Ugly Strategies for Preparedness – A Report From the Field date: 2020-09-27 journal: Disaster medicine and public health preparedness DOI: 10.1017/dmp.2020.261 sha: doc_id: 320895 cord_uid: y6pzrbdi The emergence of coronavirus disease 2019 (COVID-19), a novel unknown virus that is challenging whole countries all over the world, has prompted different strategies from various governments. Clearly, given the high contagious characteristic of the virus in combination with communications and travel (air transport in particular), this had a potential to easily accelerate the spread of such diseases.
    keywords: covid-19; disease; iran; virus
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        item: #5162 of 7819
          id: cord-320902-1hfxju5f
      author: Filocamo, Giovanni
       title: Use of anakinra in severe COVID-19: a case report
        date: 2020-05-11
       words: 1442
      flesch: 34
     summary: While the former accounts for 80% of cases, severe disease with acute respiratory distress syndrome (ARDS) and critical disease with respiratory failure and/or multiple organ dysfunction are diagnosed in 15-30% and 5% of COVID-19 patients, respectively (1). To date, May the 5th 2020, 12 clinical trials on anakinra in COVID-19 patients are registered on ClinicalTrials.gov, 7 of them recruiting patients.
    keywords: anakinra; covid-19; patients; treatment
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        item: #5163 of 7819
          id: cord-320912-jfeu4tho
      author: Fukui, M.
       title: Power Laws in Superspreading Events: Evidence from Coronavirus Outbreaks and Implications for SIR Models
        date: 2020-06-12
       words: 11778
      flesch: 55
     summary: We then extend an otherwise standard SIR model with estimated power law distributions, and show that idiosyncratic uncertainties in SSEs will lead to large aggregate uncertainties in infection dynamics, even with large populations. Under thin-tailed distributions, such as the estimated negative binomial distribution or power law distribution with α = 2, the epidemiological outcomes will be essentially predictable.
    keywords: data; distribution; infection; law; mean; power; preprint; sses
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        item: #5164 of 7819
          id: cord-320920-mceoozy8
      author: Ali, Zain
       title: Acute COVID-19 Induced Fulminant Systemic Vascular Thrombosis: A Novel Entity
        date: 2020-08-14
       words: 1150
      flesch: 26
     summary: The rise in d-dimer levels tracked with inflammatory biomarkers (CRP), reflecting both coagulopathy and vascular inflammation, a cause for acute COVID-19 related fulminant systemic vascular thrombosis (ACoFSVT). [1] [2] [3] Here, we invoke a new variant of coagulopathy, acute COVID-19 induced fulminant systemic vascular thrombosis (ACoFSVT) characterized by a rapid, widespread, massive peripheral arteriovenous coagulopathy.
    keywords: acofsvt; acute; covid-19; thrombosis
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        item: #5165 of 7819
          id: cord-320930-9yiu0080
      author: Liu, Zeming
       title: Association Between Diabetes and COVID-19: A Retrospective Observational Study With a Large Sample of 1,880 Cases in Leishenshan Hospital, Wuhan
        date: 2020-07-14
       words: 3153
      flesch: 46
     summary: We found that COVID-19 patients with DM were older and the proportion of patients with cardiovascular disease were higher among COVID-19 patients with DM than COVID-19 patients without DM. Conclusions: Our study results suggested that diabetes had no effect on the prognosis of COVID-19 patients but had a negative association with their clinical courses.
    keywords: cases; covid-19; diabetes; disease; patients; study
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        item: #5166 of 7819
          id: cord-320935-3n157yl4
      author: Kumar, Manish
       title: Making Waves Perspectives of Modelling and Monitoring of SARS-CoV-2 in Aquatic Environment for COVID-19 Pandemic
        date: 2020-09-12
       words: 6629
      flesch: 37
     summary: Although SARS viruses are of zoonotic origin and several countries have already facing secondary transmission of SARS-COV-2, developing an early warning system always presents a challenge. Previous studies have highlighted the persistence of coronavirus and SARS virus in the wastewater, which ranged from hours to several days in the absence of disinfection practices [31, 37] .
    keywords: coronavirus; cov-2; covid-19; disease; infection; models; patients; population; sars; spread; temperature; time; transmission; virus; wastewater
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        item: #5167 of 7819
          id: cord-320945-swr3l0ur
      author: Liu, Zhenghong
       title: Dynamic emergency department response to the evolving COVID‐19 pandemic: the experience of a tertiary hospital in Singapore
        date: 2020-09-25
       words: 3374
      flesch: 43
     summary: Despite extensive epidemiologic investigations, no evidence of healthcare-associated transmission of COVID-19 was detected at the ED level, and <1% of COVID-19 cases (0.23%, 3/1257) were managed outside of the designated fever areas in the ED, likely because of the broad criteria used to identify suspected COVID-19 cases. To date, Singapore has faced several waves of COVID-19 patients, each with distinct epidemiology.
    keywords: area; cases; covid-19; hospital; patients; response; risk
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        item: #5168 of 7819
          id: cord-320964-1gg33gdn
      author: Sampieri, Clara Luz
       title: Revisión de nuevas evidencias acerca de la posible transmisión vertical de la COVID-19
        date: 2020-06-20
       words: 4039
      flesch: 34
     summary: El segundo estudio es un informe de un caso de una mujer infectada a las 7 semanas de gestación, cuyas muestras de leche a los 12 y 30 días posparto fueron negativas para anticuerpos contra el SARS-CoV-2 y el recién nacido dio negativo; sin embargo, se desconocen los detalles de la recogida de las muestras de leche 40 . Sus características patogénicas y de transmisión hicieron que la Organización Mundial de la Salud declarara una emergencia de salud pública de interés internacional en enero de 2020, y el 11 de marzo, dada la propagación y la gravedad de la COVID-19, declaró que estas eran características propias de una pandemia, la primera causada por un coronavirus 4 .
    keywords: casos; con; coronavirus; cov-2; covid-19; del; entre; estudios; las; leche; los; madre; muestras; para; placenta; por; que; sars; transmisión; una; vertical
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        item: #5169 of 7819
          id: cord-320970-ru2iw0py
      author: Peeling, Rosanna W
       title: Serology testing in the COVID-19 pandemic response
        date: 2020-07-17
       words: 3672
      flesch: 43
     summary: Yet the scarcity of knowledge on the dynamics of the immune response to infection has led to hesitation on recommending the use of rapid immunodiagnostic tests, even though rapid serology tests are commercially available and scalable. This research should inform control programmes of the required performance and utility of rapid serology tests, which, when applied specifically for appropriate public health measures to then be put in place, can make a huge difference.
    keywords: antibody; covid-19; patients; serology; testing; tests; use
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        item: #5170 of 7819
          id: cord-320980-srpgcy4b
      author: Aldila, Dipo
       title: A mathematical study on the spread of COVID-19 considering social distancing and rapid assessment : The case of Jakarta, Indonesia
        date: 2020-06-28
       words: 6954
      flesch: 64
     summary: It can be seen that if social distancing intervention maintained for a longer period of time, then the outbreak of COVID-19 in Jakarta will be reduced significantly, and delayed. As a result, identifying critical model parameters in this study based on computational simulations 225 is an effective way to further study the model practically and theoretically and give some suggestions for future improvements of the COVID-19 transmissions, interventions and controlling the spread of disease.
    keywords: + φ; covid-19; µ +
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        item: #5171 of 7819
          id: cord-320994-3ahwc3aq
      author: Miyashita, Hirotaka
       title: Do Patients with Cancer Have a Poorer Prognosis of COVID-19? An Experience in New York City.
        date: 2020-04-21
       words: 419
      flesch: 47
     summary: Zhang However, the mortality rates of COVID-19 in cancer patients were lower than those in patients without cancer in age groups older than 50 years, though they were not statistically significant. 4, 5 Nevertheless, in young populations, whose mortality rate from COVID-19 is very low in general, baseline fragility in cancer patients may lead to a relatively higher rate of deaths.
    keywords: cancer; patients
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        item: #5172 of 7819
          id: cord-321030-isc3p46t
      author: Rodriguez Socarrás, Moises
       title: Telemedicine and Smart Working: Recommendations of the European Association of Urology
        date: 2020-07-10
       words: 4621
      flesch: 47
     summary: It is expected that many patients will spend long periods of confinement at home, so the occurrence/exacerbation of urological symptoms or the interruption of follow-up may generate anxiety and a feeling of helplessness. Many patients will need requisitions for laboratory or imaging tests, some of them with relative urgency.
    keywords: care; covid-19; data; face; health; pandemic; patients; telemedicine; urology; use; working
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        item: #5173 of 7819
          id: cord-321044-pfooy6g3
      author: Chiu, Joanne S.
       title: Kawasaki Disease Features and Myocarditis in a Patient with COVID-19
        date: 2020-06-15
       words: 1112
      flesch: 47
     summary: Given that the pediatric intensive care unit at our institution had been converted to adult COVID-19 patients, the patient was transferred to an outside institution. Although prior reports have reported that over 90% of pediatric cases are asymptomatic, mild, or moderate [1] , it is critically important for physicians to recognize the possibility of severe presentations in pediatric patients.
    keywords: covid-19; disease; myocarditis
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        item: #5174 of 7819
          id: cord-321062-j4cd1uho
      author: Kottlors, Jonathan
       title: Body composition on Low Dose Chest CT is a Significant Predictor of Poor Clinical Outcome in COVID-19 Disease - a Multicenter Feasibility Study
        date: 2020-09-09
       words: 3787
      flesch: 39
     summary: FMR as potential surrogate of body composition and obesity can be easily determined in initial LDCT of COVID-19 patients. In multivariate logistic regression analysis, FMR (p < .001) in addition to age (p < .01), was found to be a significant predictor of the necessity for ICU treatment of COVID-19 patients.
    keywords: body; composition; covid-19; ldct; muscle; patients
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        item: #5175 of 7819
          id: cord-321074-7jfy8cn6
      author: Caruso, Damiano
       title: Quantitative Chest CT analysis in discriminating COVID-19 from non-COVID-19 patients
        date: 2020-10-12
       words: 2924
      flesch: 40
     summary: CT quantification of ground-glass opacities and fibrotic alterations is able to identify COVID-19 patients with moderate accuracy and may help radiologists to overcome low specificity of Chest CT. Future application might also include COVID-19 CT follow-up with a quantitative assessment of lung impairment as expression of worsening, stability or healing of lung parenchyma.
    keywords: analysis; chest; covid-19; patients; results
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        item: #5176 of 7819
          id: cord-321085-u0pl323l
      author: Kumar, Karan
       title: Elevated Liver Chemistries in COVID-19—Is It Not a Concern?
        date: 2020-09-14
       words: 609
      flesch: 47
     summary: A multicenter, retrospective, crosssectional study Systematic review with meta-analysis: Liver manifestations and outcomes in COVID-19 Acute liver injury in COVID-19: Prevalence and association with clinical outcomes in a large US cohort Liver injury is independently associated with adverse clinical outcomes in patients with COVID-19 Laboratory parameters in detection of COVID-19 patients with positive RT-PCR; a diagnostic accuracy study The incidence of elevated liver chemistries in COVID-19 patients at the time of admission is 24.1% (95% confidence interval
    keywords: covid-19; liver
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        item: #5177 of 7819
          id: cord-321088-5gu7rnhj
      author: Collins, Caitlin
       title: Stress and the Surgical Resident in the COVID-19 Pandemic
        date: 2020-07-25
       words: 4004
      flesch: 38
     summary: On a more personal level, surgical resident anxieties seemed to focus on concern for others-specifically, for loved ones whom they are not able to directly care for during this time. These unprecedented changes, along with the stresses inherent in the COVID-19 pandemic, create a climate where stress and anxiety are exacerbated among surgical residents.
    keywords: anxiety; covid-19; hospital; operative; pandemic; residents; surgery; survey; training
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        item: #5178 of 7819
          id: cord-321089-x85tg8g5
      author: Wilson, Jacob M.
       title: Quantifying the Backlog of Total Hip and Knee Arthroplasty Cases: Predicting the Impact of COVID-19
        date: 2020-11-04
       words: 3197
      flesch: 50
     summary: Similarly, because COVID-19 is unpredictable, the ability for healthcare systems to accommodate an increase in elective surgery volume will vary by region, institutional capacity, and resource availability. As we were interested only in non-urgent arthroplasty cases, ICD diagnosis codes were used to exclude patients undergoing arthroplasty for fracture or infection.
    keywords: arthroplasty; covid-19; patients; surgery; tha; tka; volume
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        item: #5179 of 7819
          id: cord-321097-fw05hcr4
      author: Annie, Frank
       title: Prevalence and Outcomes of Acute Ischemic Stroke Among Patients ≤ 50 Years of Age with Laboratory Confirmed COVID-19 Infection
        date: 2020-06-14
       words: 468
      flesch: 51
     summary: In this focused analysis, we investigated the incidence and outcomes of acute ischemic stroke in young adults using a multinational database. The incidence of acute ischemic stroke was 64/9,358 (0.7%).
    keywords: covid-19; stroke
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        item: #5180 of 7819
          id: cord-321098-j3glby40
      author: Bodrud-Doza, Md.
       title: Psychosocial and Socio-Economic Crisis in Bangladesh Due to COVID-19 Pandemic: A Perception-Based Assessment
        date: 2020-06-26
       words: 8966
      flesch: 44
     summary: However, a surge of COVID-19 outbreaks in all inhabitable continents, with 84,187 deaths alone in the USA, indicates that the infection had passed the tipping point (1, 6) . The DGHS, on the other hand, is the responsible body for the coordination of testing and sample collections of COVID-19 patients (10) .
    keywords: bangladesh; covid-19; facilities; fear; government; healthcare; issues; mean; outbreak; pandemic; people; respondents; social; system; value
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        item: #5181 of 7819
          id: cord-321137-nxd8i7uh
      author: White, Michael D.
       title: Policing a Pandemic: Stay-at-Home Orders and What they Mean for the Police
        date: 2020-06-09
       words: 5723
      flesch: 46
     summary: Beyond this legal assessment, there is another important lens for considering the appropriateness of police actions against potential SaHOs/SiPOs violators: police legitimacy. Second, unlike in other countries where police can respond to emergency legislation that empowers them to enforce lockdown orders aggressively (see Cave & Dahir, 2020) , enforcement of public health orders in the United States is complicated by the Fourth Amendment since that constitutional provision limits police authority to stop, question, frisk, or arrest people absent certain quanta of proof (White & Fradella, 2016) .
    keywords: authority; covid-19; enforcement; health; law; orders; people; police; public; sahos; sipos; state
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        item: #5182 of 7819
          id: cord-321149-hffj7s4o
      author: Schmidt, Matthieu
       title: Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome associated with COVID-19: a retrospective cohort study
        date: 2020-08-13
       words: 5370
      flesch: 41
     summary: Systemic inflammatory response syndrome is a major contributor to COVID-19-associated coagulopathy: insights from a prospective single center cohort study Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Severe pulmonary embolism in COVID-19 patients: a call for increased awareness High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Mechanical ventilation management during extracorporeal membrane oxygenation for acute respiratory distress syndrome. Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome and posterior probability of mortality benefit in a post hoc Bayesian analysis of a randomized clinical trial Surviving sepsis campaign: guidelines on the management of critically ill adults with coronavirus disease 2019 (COVID-19) Extracorporeal life support organization coronavirus disease 2019 interim guidelines: a consensus document from an international group of interdisciplinary extracorporeal membrane oxygenation providers Preparing for the most critically ill patients with COVID-19: the potential role of extracorporeal membrane oxygenation Planning and provision of ECMO services for severe ARDS during the COVID-19 pandemic and other outbreaks of emerging infectious diseases Poor survival with extracorporeal membrane oxygenation in acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19): pooled analysis of early reports Extracorporeal membrane oxygenation for coronavirus disease 2019-induced acute respiratory distress syndrome: a multicenter descriptive study COVID-19, ECMO, and lymphopenia: a word of caution Clinical management of severe acute respiratory infection when COVID-19 disease is suspected The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material Emergency circulatory support in refractory cardiogenic shock patients in remote institutions: a pilot study (the cardiac-RESCUE program) Retrieval of severe acute respiratory failure patients on extracorporeal membrane oxygenation: any impact on their outcomes?
    keywords: ards; care; covid-19; ecmo; extracorporeal; hospital; icu; membrane; oxygenation; patients; pressure; state
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        item: #5183 of 7819
          id: cord-321176-b4o3nba6
      author: Ong, P. M.
       title: COVID-19 Medical Vulnerability Indicators: A Local Data Model for Equity in Public Health Decision-Making
        date: 2020-11-04
       words: 8983
      flesch: 45
     summary: ----INSERT FIGURE 9 ABOUT HERE---- We further analyzed the four indicators of COVID-19 vulnerability by categorizing ZCTA's into racial majorities and comparing their average vulnerability scores. We utilize the ZCTA because our main source of population level health data, the California Health Interview Survey was only available to use in ZCTA format.
    keywords: author; covid-19; funder; health; indicators; license; medrxiv preprint; neighborhoods; perpetuity; population; preprint; vulnerability
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        item: #5184 of 7819
          id: cord-321177-ywkkcagd
      author: Tamari, Keisuke
       title: Nationwide survey of COVID-19 prevention measures in Japanese radiotherapy departments via online questionnaire for radiation oncologists
        date: 2020-05-29
       words: 996
      flesch: 44
     summary: key: cord-321177-ywkkcagd authors: Tamari, Keisuke; Nagata, Yasushi; Nishiki, Shingo; Nakamura, Satoaki; Ogawa, Kazuhiko; Uno, Takashi title: Nationwide survey of COVID-19 prevention measures in Japanese radiotherapy departments via online questionnaire for radiation oncologists date: 2020-05-29 journal: Here, we investigate the current status of the practice of COVID-19 prevention measures in Japanese radiotherapy departments using an online questionnaire.
    keywords: covid-19; patients; radiotherapy
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        item: #5185 of 7819
          id: cord-321181-bqdsfgdc
      author: Garitano, Ignacio
       title: Estimando el número de casos de COVID-19 mediante una herramienta web: resultados de la primera semana del proyecto "Covid-19 Trends" en Euskadi
        date: 2020-05-21
       words: 3193
      flesch: 49
     summary: El director general de la OMS, en la reunión del 30 de enero de 2020 del Comité de Emergencias del Reglamento Sanitario Internacional, (aprobado en 2005), declaró el brote de SARS-CoV-2 como una Emergencia de Salud Publica de Importancia Internacional (ESPII) España notificó su primer caso el 31 de enero de 2020 en un turista en la isla de La Gomera
    keywords: 2020; casos; como; con; covid-19; cuestionario; datos; del; este; euskadi; las; los; marzo; para; pcr; por; que; una
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        item: #5186 of 7819
          id: cord-321194-xi4zy5ow
      author: Allam, Zaheer
       title: The Third 50 Days: A Detailed Chronological Timeline and Extensive Review of Literature Documenting the COVID-19 Pandemic From Day 100 to Day 150
        date: 2020-07-24
       words: 17937
      flesch: 52
     summary: For instance, as of 28th, the total number of reported cases in Africa (35,676) was far much less than the total number of deaths (59,266) reported in the United States on the same day. By April 28, it became official that the number of COVID-19 infection cases had exceeded the 3 million (the WHO reported 2.95 million cases and 202,597 deaths) people and caused the death of over 211,000 people globally.
    keywords: april; cases; china; coronavirus; countries; country; covid-19; day; days; deaths; disease; health; italy; lockdown; measures; new; number; pandemic; people; president; region; report; situation; states; total; trump; united; world
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        item: #5187 of 7819
          id: cord-321231-zlpa3x2x
      author: Anand, Pratima
       title: Clinical profile, viral load, management and outcome of neonates born to COVID 19 positive mothers: a tertiary care centre experience from India
        date: 2020-09-10
       words: 6899
      flesch: 47
     summary: The report has the strengths of elaborate clinical details and the fact that all neonates born to positive mothers could be tested (unlike previous reports where the proportion of neonates could not be tested). a E gene cycle thresholds in maternal neonatal dyads in COVID positive neonates.
    keywords: birth; covid; covid-19; day; delivery; infection; load; mother; neonatal; neonates; study; transmission
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        item: #5188 of 7819
          id: cord-321240-f6qh4fva
      author: Adekunle, Ibrahim Ayoade
       title: Modelling spatial variations of coronavirus disease (COVID-19) in Africa
        date: 2020-08-10
       words: 2249
      flesch: 49
     summary: In Europe, Italy, with 159,516 confirmed cases and 20,465 deaths although relatively less compared to confirmed cases in Spain with 169,496 with 17,489 deaths remains the hardest hit because of their superior coronavirus reported death cases. We constructed spatial variations of clusters that examined the nexus between COVID-19 attributable deaths and confirmed cases.
    keywords: africa; cases; covid-19; deaths; human; number
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        item: #5189 of 7819
          id: cord-321258-fj9nel2z
      author: Huynh, Giao
       title: Knowledge, Attitude, and Practices Regarding COVID-19 Among Chronic Illness Patients at Outpatient Departments in Ho Chi Minh City, Vietnam
        date: 2020-09-14
       words: 3016
      flesch: 52
     summary: The first section elicited information on demographic characteristics including age, gender, occupation, education, and the source information of COVID-19 knowledge including types of face masks. World Health Organization Getting your workplace ready for COVID-19 Ministry of Health in Vietnam Combating the COVID-19 epidemic: experiences from Vietnam Social responses for older people in COVID-19 pandemic: experience from Vietnam COVID-19 and NCDs How to Protect Yourself attitude and practice towards SARS Middle east respiratory syndrome (MERS): comparing the knowledge, attitude and practices of different health care workers Public knowledge, attitudes and practices towards COVID-19: a cross-sectional study in Malaysia Knowledge, attitude and practice towards COVID-19 among chronic disease patients at Addis Zemen Hospital, Northwest Ethiopia WHO.
    keywords: attitude; covid-19; knowledge; participants; practices; study
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        item: #5190 of 7819
          id: cord-321259-wio2b49i
      author: Carmona-Gutierrez, Didac
       title: Digesting the crisis: autophagy and coronaviruses
        date: 2020-05-04
       words: 4365
      flesch: 26
     summary: lifespan extension by the natural polyamine spermidine Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes Polyamines and Their Role in Virus Infection Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses The Interplay Between Pattern Recognition Receptors and Autophagy in Inflammation Pathogen recognition and innate immunity Autophagy Promotes MHC Class II Presentation of Peptides from Intracellular Source Proteins Autophagy Beyond Intracellular MHC Class II Antigen Presentation Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection The relationship between autophagy and the immune system and its applications for tumor immunotherapy Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance Autophagy is a critical regulator of memory CD8+ T cell formation Polyamines Control eIF5A Autophagy and inflammasomes Secretory autophagy Human placental trophoblasts confer viral resistance to recipient cells Human TANK-binding kinase 1 is required for early autophagy induction upon herpes simplex virus 1 infection A discovery platform for the identification of caloric restriction mimetics with broad health-improving effects Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential Given the devastating consequences of the current COVID-19 pandemic, the question arises whether manipulating autophagy might be an expedient approach to fight the novel coronavirus SARS-CoV-2.
    keywords: autophagy; cell; chloroquine; coronavirus; covid-19; covs; disease; effects; induction; infection; replication; sars; spermidine
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        item: #5191 of 7819
          id: cord-321267-ihd30qi0
      author: Daughton, Christian G.
       title: Natural experiment concept to accelerate the Re-purposing of existing therapeutics for Covid-19
        date: 2020-05-15
       words: 5354
      flesch: 37
     summary: Many different scenarios can be hypothesized for how drug usage might be associated with Covid-19 clinical outcomes. This would entail a more ambitious data collection effort involving collaboration with industrial and environmental toxicologists to extend the utility beyond drug usage by broadening the exposome and incorporating known occupational and environmental hazards.
    keywords: covid-19; disease; drugs; infection; negative; nerd; potential; test; testing; usage
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        item: #5192 of 7819
          id: cord-321282-fyhkok3t
      author: Beglaibter, Nahum
       title: Practices and attitudes of bariatric surgeons in Israel during the first phase of the COVID-19 pandemic
        date: 2020-10-30
       words: 4170
      flesch: 49
     summary: This, and the fact that the decree was never enforced on public hospital opting continuing to perform elective bariatric surgery, may give the impression that obese patients and staff safety were not considered by themselves a reason to stop elective surgery. Only 14 (28%) surgeons reported applying changes to the post-operative supervision of BS patients during the pandemic.
    keywords: covid-19; elective; pandemic; patients; public; sector; surgeons; surgery
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        item: #5193 of 7819
          id: cord-321302-eowo2mt0
      author: Spaetgens, Bart
       title: The Post-Acute and Long-Term Care Crisis in the Aftermath of COVID-19: a Dutch Perspective
        date: 2020-06-29
       words: 388
      flesch: 42
     summary: Morbidity and 7 mortality in nursing homes that suffered outbreaks of COVID-19 has been high 8 despite the fact that Dutch nursing home care benefits from well-developed care 9 infrastructures that are fully integrated in the national health sector. key: cord-321302-eowo2mt0 authors: Spaetgens, Bart; Brouns, Steffie H.; Schols, Jos M.G.A. title: The Post-Acute and Long-Term Care Crisis in the Aftermath of COVID-19: a Dutch Perspective date: 2020-06-29 journal: J Am Med Dir Assoc DOI: 10.1016/j.jamda.2020.06.045 sha: doc_id: 321302 cord_uid: eowo2mt0 nan To the Editor: 1 We read with great interest the article by Laxton In the Netherlands, the peak of the first wave of the pandemic seems to be behind us 5 and it is now becoming apparent how hard the nursing home population has been hit 6 and how disruptive the pandemic is for Dutch nursing homes as well.
    keywords: care; nursing
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        item: #5194 of 7819
          id: cord-321311-v2i1caug
      author: Weller, Michael
       title: How we treat patients with brain tumour during the COVID-19 pandemic
        date: 2020-05-13
       words: 2746
      flesch: 33
     summary: Patients with curatively operated tumours, for example, schwannomas or meningiomas, who have no evidence of recurrent disease must not be placed in the same category as patients with recurrent glioblastoma, but having a brain tumour is still often perceived as stigmatising. key: cord-321311-v2i1caug authors: Weller, Michael; Preusser, Matthias title: How we treat patients with brain tumour during the COVID-19 pandemic date: 2020-05-13 journal: ESMO Open DOI: 10.1136/esmoopen-2020-000789 sha: doc_id: 321311 cord_uid: v2i1caug The COVID-19 pandemic has created major insecurities regarding whether we can and should maintain the current standards of diagnosis and treatment and access to care for patients with cancer.
    keywords: cancer; care; covid-19; patients; risk
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        item: #5195 of 7819
          id: cord-321315-bzmokdzk
      author: Tanacan, Atakan
       title: The Rate of SARS-CoV-2 Positivity in Asymptomatic Pregnant Women Admitted to Hospital for Delivery: Experience of A Pandemic Center in Turkey
        date: 2020-07-30
       words: 2137
      flesch: 47
     summary: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Effects of coronavirus disease 2019 (COVID-19) on maternal, perinatal and neonatal outcomes: a systematic review Coronavirus disease 2019 in pregnant women: a report based on 116 cases COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of SARS-CoV-2 in pregnancy: symptomatic pregnant women are only the tip of the iceberg Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Covid-19 during pregnancy: a case series from an universally tested population from the north of Portugal None. Eur J Obstet Gynecol Reprod Biol DOI: 10.1016/j.ejogrb.2020.07.051 sha: doc_id: 321315 cord_uid: bzmokdzk OBJECTIVE: To investigate the rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positivity in asymptomatic pregnant women admitted to hospital for delivery in a Turkish pandemic center.
    keywords: covid-19; delivery; pregnancy; risk; sars; women
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        item: #5196 of 7819
          id: cord-321379-7bpl5n3j
      author: Singh, Sweta
       title: Coronavirus disease 2019 drug discovery through molecular docking
        date: 2020-06-03
       words: 3996
      flesch: 53
     summary: Remdesivir was detected as COVID-19 inhibitory drug via virtual screening method 6 . The rest of the molecules could also be used as COVID-19 inhibitory drugs after further evaluation.
    keywords: 6m03; authors; binding; covid-19; docking; drugs; energy; molecules; protease; results
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        item: #5197 of 7819
          id: cord-321380-e5zq15hz
      author: del Campo, P. Lázaro
       title: No transmission of SARS-CoV-2 in a patient undergoing allogeneic Hematopoietic Cell Transplantation from a matched-related donor with unknown COVID-19
        date: 2020-08-24
       words: 1888
      flesch: 45
     summary: Also, viral RNA could be isolated in plasma or serum from COVID-19 asymptomatic patients in a very low concentration [4] . In conclusion, blood products including hematopoietic stem cells are safe in the context of COVID-19 pandemic.
    keywords: blood; cov-2; covid-19; sars
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        item: #5198 of 7819
          id: cord-321387-5epa1bb8
      author: Altuntas, Fevzi
       title: Convalescent Plasma Therapy in Patients with COVID-19
        date: 2020-09-19
       words: 2386
      flesch: 52
     summary: Anti-SARS-CoV-2 Ig G antibodies were not routinely screened in COVID-19 patients before CP treatment. As of 22 May 2020, there have been 154.500 laboratory confirmed COVID-19 patients in Turkey.
    keywords: covid-19; days; group; patients; treatment
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        item: #5199 of 7819
          id: cord-321402-7a04kx5n
      author: Rezakhani, Leila
       title: Mesenchymal stem cell (MSC)-derived exosomes as a cell-free therapy for Patients Infected with COVID-19: Real Opportunities and Range of Promises
        date: 2020-11-12
       words: 2988
      flesch: 37
     summary: clinical trials highlight the potential benefits of stem cell secretome therapies for COVID-19 patients. An investigation of topics and trends of tracheal replacement studies using co-occurrence analysis Mesenchymal stem cells: time to change the name!
    keywords: cells; covid-19; exosomes; mesenchymal; mscs; stem; treatment
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        item: #5200 of 7819
          id: cord-321403-fe4vgwz8
      author: Bellini, Maria Irene
       title: Kidney transplantation and the lock‐down effect
        date: 2020-05-09
       words: 584
      flesch: 38
     summary: Preliminary data from Italy show already a 30% reduction in kidney transplant activity during the lock-down, in parallel with ICU COVID-19 beds crisis ( Figure 1 ). patients in the intensive care unit (ICU), kidney transplant activity is expected to be run again.
    keywords: covid-19; transplant
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        item: #5201 of 7819
          id: cord-321412-6g3obmzc
      author: Khamis, Faryal
       title: Therapeutic Plasma Exchange in Adults with Severe COVID-19 Infection
        date: 2020-06-23
       words: 3143
      flesch: 45
     summary: The use of TPE in severe COVID-19 patients has been associated with improved outcomes, however, randomized controlled clinical trials are warranted to draw final conclusive findings. The declare no conflict of interest J o u r n a l P r e -p r o o f J o u r n a l P r e -p r o o f COVID-19 pandemic by country and territory A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19 Available at Sepsis and septic shock: endothelial molecular pathogenesis associated with vascular microthrombotic disease Effective treatment of severe COVID-19 patients with tocilizumab Early Safety Indicators of COVID-19 Convalescent Plasma in 5,000 Patients Early therapeutic plasma exchange in septic shock: a prospective open-label nonrandomized pilot study focusing on safety, hemodynamics, vascular barrier function, and biologic markers Plasmapheresis in severe sepsis and septic shock: a prospective, randomised, controlled trial The efficacy and safety of plasma exchange in patients with sepsis and septic shock: a systematic review and meta-analysis Use of therapeutic plasma exchange as a rescue therapy in 2009 pH1N1 influenza A--an associated respiratory failure and hemodynamic shock The therapeutic efficacy of adjunct therapeutic plasma exchange for septic shock with multiple organ failure: a single center retrospective review Successful treatment of plasma exchange followed by intravenous immunogloblin in a critically ill patient with 2019 novel coronavirus infection Efficacy of therapeutic plasma exchange in severe COVID-19 patients Acute respiratory distress syndrome: the Berlin Definition Human infection with novel corona virus (COVID-19)-7.
    keywords: exchange; patients; plasma; tpe
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        item: #5202 of 7819
          id: cord-321440-sts3re6p
      author: Klein, Sebastian J.
       title: Unrecognized diabetes in critically ill COVID-19 patients
        date: 2020-07-09
       words: 903
      flesch: 46
     summary: Recent data demonstrating viral particles in endothelial cells of several organs suggest endotheliitis as a possible mechanism of organ dysfunction leading to critical illness in COVID-19 patients which may be aggravated by endothelial Abbreviations: IQR interquartile range, BMI body mass index, HbA1c glycated hemoglobin, CRP C-reactive protein, IL-6 interleukin-6, COPD chronic obstructive pulmonary disease, SARS-CoV-2 severe acute respiratory syndrome coronavirus Patients were included in the analysis if they were 18 years of age or older, had confirmed COVID-19, and were admitted to an intensive care unit from March 11 to April 29, 2020.
    keywords: covid-19; diabetes; hba1c; patients
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        item: #5203 of 7819
          id: cord-321455-ooouqna7
      author: Li, Tao
       title: Characteristics of laboratory indexes in COVID-19 patients with non-severe symptoms in Hefei City, China: diagnostic value in organ injuries
        date: 2020-07-01
       words: 2118
      flesch: 44
     summary: Statistical charts were drawn using GraphPad Prism 8. The LYMPH, EO, and BSO counts in patients with COVID-19 were significantly lower, compared with the controls on the 1st, 4th, 7th, and 10th days of admission, while the MONO counts were significantly higher in COVID-19 patients ( Fig. 1a-d) . *Because the concentrations of IL-1β in patients and IL-10 in controls are below the lower limit of the measurement range, we use the lower limit value of the measurement range as statistical data Analyses of hemostasis, coagulation, and fibrinolysisrelated systems APTT and PT for COVID-19 patients were significantly longer than those in controls, and FDP, D-D, FIB, and PT-INR were higher compared with those in the controls (Table 2 and Fig. 4a f).
    keywords: admission; controls; covid-19; patients; sars; study
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        item: #5204 of 7819
          id: cord-321459-5atonb89
      author: Llalle, Wildor Samir Cubas
       title: Impact on the Thoracic and Cardiovascular Surgery Residents’ Learning Curve During the COVID-19 Pandemic
        date: 2020
       words: 919
      flesch: 14
     summary: Some organizations in the world related to our surgical field have been providing a series of surgical learning platforms free of charge by highly prestigious mentor surgeons, to strengthen and contribute to continuing education among their members and the public of interest; this is the case of the Society of Thoracic Surgeons (STS, https://www.sts.org/learning-center/webinars), European Association for Cardio-Thoracic Surgery (EACTS, http:// www.eacts.org/education Impact of the coronavirus (COVID-19) pandemic on surgical practice -part 2 (surgical prioritisation) Practical techniques to adapt surgical resident education to the COVID-19 era Slowdown of urology residents' learning curve during the COVID-19 emergency Impact of the COVID-19 pandemic on urology residency training in Italy Emerging role of online virtual teaching resources for medical student education in plastic surgery:
    keywords: covid-19; learning; thoracic
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        item: #5205 of 7819
          id: cord-321461-1s3y9kc5
      author: Rajdev, Kartikeya
       title: Acute Ischemic and Hemorrhagic Stroke in COVID-19: Mounting Evidence
        date: 2020-08-31
       words: 2474
      flesch: 42
     summary: Physicians should have a low threshold for suspecting stroke in COVID-19 patients, and close observation should be kept on such patients particularly those with clinical evidence of traditional risk factors. However, treating physicians should have a low threshold for suspecting stroke in COVID-19 patients, and close observation should be kept on such patients particularly those with clinical evidence of traditional risk factors.
    keywords: ace2; covid-19; ischemic; patient; risk; stroke
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        item: #5206 of 7819
          id: cord-321472-n4nnmlv1
      author: Oliveira, E.
       title: ICU Outcomes and Survival in Patients with Severe COVID-19 in the Largest Health Care System in Central Florida
        date: 2020-08-31
       words: 4020
      flesch: 41
     summary: No evidence of rapid antiviral clearance or clinical benefit with the combination of hydroxychloroquine and azithromycin in patients with severe COVID-19 infection A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 Convalescent plasma as a potential therapy for COVID-19 Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients with Acute Respiratory Distress Syndrome: A Randomized Clinical Trial Prone positioning in severe acute respiratory distress syndrome The Surviving Sepsis Campaign Bundle: 2018 update Routine Venous Thromboembolism Prophylaxis May Be Inadequate in the Hypercoagulable State of Severe Coronavirus Disease A study on the efficacy of APACHE-IV for predicting mortality and length of stay in an intensive care unit in Iran Incidence, clinical outcomes, and transmission dynamics of severe coronavirus disease 2019 in California and Washington: prospective cohort study Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Management of COVID-19 Respiratory Distress Past and Present ARDS Mortality Rates: A Systematic Review COVID-19 and African Americans The Relationship of Health Insurance and Mortality: Is Lack of Insurance deadly? Effects of temperature variation and humidity on the death of COVID-19 in Wuhan Innovation and Transformation in the Response to Covid-19: Seven Areas Where Clinicians Need to Lead Clinical outcomes in COVID-19 patients treated with tocilizumab: An individual patient data systematic review Treatment with Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection Poor survival with extracorporeal membrane oxygenation in acute respiratory distress syndrome (ARDS) due to coronavirus disease 2019 (COVID-19): Pooled analysis of early reports Evaluating the efficacy of dexamethasone in the treatment of patients with persistent acute respiratory distress syndrome: study protocol for a randomized controlled trial Dexamethasone treatment for the acute respiratory distress syndrome: a multicenter, randomized controlled trial We would like to acknowledge the following AdventHealth Critical Care Consortium Research Observations from Wuhan have shown mortality rates of approximately 52% in COVID-19 patients with ARDS
    keywords: care; covid-19; icu; license; mortality; outcomes; patients; preprint; study
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        item: #5207 of 7819
          id: cord-321497-c7l88gjn
      author: Tull, Matthew T.
       title: Psychological Outcomes Associated with Stay-at-Home Orders and the Perceived Impact of COVID-19 on Daily Life
        date: 2020-05-12
       words: 5754
      flesch: 40
     summary: (0 = no; 1 = yes); COVID-19 impact = To what extent has the situation associated with COVID-19 affected the way you live your life? (0 = no; 1 = yes); COVID-19 impact = To what extent has the situation associated with COVID-19 affected the way you live your life?; Interaction = Stay-at-home status ×
    keywords: anxiety; covid-19; health; home; impact; order
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        item: #5208 of 7819
          id: cord-321499-17n9tj70
      author: Marini, John J.
       title: Integrating the evidence: confronting the COVID-19 elephant
        date: 2020-07-25
       words: 1711
      flesch: 37
     summary: Respiratory failure often resolves slowly in the most severely ill who do survive Which available drugs and proposed anti-viral approaches for COVID-19 treatment hold the most potential for benefit or risk? Mortality rates are higher among those with diabetes, hypertension, chronic heart or lung disease, the elderly, and the morbidly obese Can we develop an effective vaccine against variants of COVID and distribute it worldwide?
    keywords: ards; covid-19; distress; lung; patients
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        item: #5209 of 7819
          id: cord-321503-w2m078r1
      author: Cardwell, Ryan
       title: COVID-19 and International Food Assistance: Policy Proposals to Keep Food Flowing
        date: 2020-06-28
       words: 3111
      flesch: 44
     summary: key: cord-321503-w2m078r1 authors: Cardwell, Ryan; Ghazalian, Pascal L. title: COVID-19 and International Food Assistance: Policy Proposals to Keep Food Flowing date: 2020-06-28 journal: World Dev DOI: 10.1016/j.worlddev.2020.105059 sha: doc_id: 321503 cord_uid: w2m078r1 The COVID-19 pandemic is increasing the need for international food assistance, and disrupting the supply and delivery of food assistance. The COVID-19 pandemic is creating a global food security crisis Need for international food assistance is rising, while supply is being constrained Donor countries may cut foreign aid budgets during economic recessions We propose policy responses to keep food assistance flowing, without increasing aid budgets Proposals include prioritizing humanitarian aid spending, exempting food assistance from trade barriers, and untying aid
    keywords: aid; assistance; countries; covid-19; donor; food; pandemic; restrictions
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        item: #5210 of 7819
          id: cord-321543-qdmvn44h
      author: Webb, J. B.
       title: Computational Simulation to Assess Patient Safety of Uncompensated COVID-19 Two-patient Ventilator Sharing Using the Pulse Physiology Engine
        date: 2020-05-26
       words: 5537
      flesch: 37
     summary: We undertook a computational simulation of dual patient ventilation with a single ventilator using a computational whole-body simulation model to produce informed clinical parameters addressing noted assumptions and assertions. [21] and no computational simulation literature to inform multiple patient shared ventilation, nor specific definition of similar mechanical support needs [16] .
    keywords: compliance; covid-19; license; lung; model; parameters; patient; preprint; pulse; simulation; ventilator
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        item: #5211 of 7819
          id: cord-321552-lsz1onrj
      author: Membrilla, Javier A.
       title: Headache as a Cardinal Symptom of Coronavirus Disease 2019: A Cross‐Sectional Study
        date: 2020-09-28
       words: 4354
      flesch: 43
     summary: In migraine patients, COVID-19 headache tends to last longer, is more severe and presents earlier in the course of the disease than in patients without migraine. We found that patients with migraine tend to have longer and more intense episodes of COVID-19 headaches.
    keywords: covid-19; headache; migraine; pain; patients; sars; study; symptoms
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        item: #5212 of 7819
          id: cord-321568-okvt1fg3
      author: Alberca, Ricardo Wesley
       title: Perspective: The Potential Effects of Naringenin in COVID-19
        date: 2020-09-25
       words: 4115
      flesch: 28
     summary: In this perspective, we summarize NAR potential anti-inflammatory role in COVID-19 associated risk factors and SARS-CoV-2 infection. Naringenin anti-inflammatory effect was also verified in radiation-induced lung injury, reducing lung inflammation and IL-1β levels (72) .
    keywords: coronavirus; cov-2; covid-19; infection; inflammation; lung; mers; model; nar; naringenin; sars; syndrome
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        item: #5213 of 7819
          id: cord-321586-lgbod553
      author: Danielli, Shaun
       title: Economic interventions to ameliorate the impact of COVID-19 on the economy and health: an international comparison
        date: 2020-07-13
       words: 1120
      flesch: 51
     summary: key: cord-321586-lgbod553 authors: Danielli, Shaun; Patria, Raman; Donnelly, Patrice; Ashrafian, Hutan; Darzi, Ara title: Economic interventions to ameliorate the impact of COVID-19 on the economy and health: an international comparison date: 2020-07-13 journal: J Public Health (Oxf) DOI: 10.1093/pubmed/fdaa104 sha: doc_id: 321586 cord_uid: lgbod553 BACKGROUND: The strategies and scale of economic interventions have been broad, ranging from 2.5% to a reported 50% of Gross Domestic Product.
    keywords: countries; covid-19; health
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        item: #5214 of 7819
          id: cord-321593-x6mdkyq6
      author: Dunnick, N. Reed
       title: Most Adaptable to Change
        date: 2020-05-06
       words: 1525
      flesch: 48
     summary: Medical imaging has an important role in helping to reach an accurate diagnosis and initiating medical care, and the pressure to provide immediate interpretations is increasing. Many medical centers have created teams of physicians who alternate covering their services.
    keywords: care; covid-19; imaging; radiologists; radiology
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        item: #5215 of 7819
          id: cord-321598-ae241pmd
      author: de Vries, A.P.J.
       title: Immediate impact of COVID-19 on transplant activity in the Netherlands
        date: 2020-05-01
       words: 2283
      flesch: 41
     summary: Notably, prioritization of health care services for COVID-19 care raises concerns about allocation of resources to deliver care for transplant patients who might otherwise have excellent 1-year and 10-year survival rates. Early Description of Coronavirus Community respiratory virus infections in immunocompromised patients: hematopoietic stem cell and solid organ transplant recipients, and individuals with human immunodeficiency virus infection Treatment outcomes for patients with Middle Eastern Respiratory Syndrome Coronavirus (MERS CoV) infection at a coronavirus referral center in the Kingdom of Saudi Arabia Coronaviruses and immunosuppressed patients.
    keywords: care; covid-19; donation; organ; patients; transplant; transplantation
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        item: #5216 of 7819
          id: cord-321633-qr2w7azj
      author: Yadav, Sanjay Kumar
       title: Rapid Scoping Review of Laparoscopic Surgery Guidelines During the COVID-19 Pandemic and Appraisal Using a Simple Quality Appraisal Tool “EMERGE”
        date: 2020-09-17
       words: 4014
      flesch: 40
     summary: The theoretical danger of virus transmission during laparoscopic surgery (LS) via surgical smoke and laparoscopy gas prompted several academic/national associations to issue laparoscopic surgery guidelines during the COVID-19 pandemic. This coupled with exclusion of their needs in laparoscopic surgery guidelines amounts to epistemic injustice [30] .
    keywords: appraisal; covid-19; evidence; global; guidelines; pandemic; review; surgery; tool
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        item: #5217 of 7819
          id: cord-321698-8q25z6ci
      author: Spratt, Daniel I
       title: COVID-19 and Hypercoagulability: Potential Impact on Management with Oral Contraceptives, Estrogen Therapy and Pregnancy
        date: 2020-07-29
       words: 827
      flesch: 30
     summary: Similar data exist for oral hormone replacement therapy (HRT) in menopausal women (6) and oral estrogen therapy in male-to-female transgender patients. Can that be applied to the as yet unsolved pathophysiology of coagulopathy with estrogen therapy and pregnancy?
    keywords: covid-19; estrogen; therapy
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        item: #5218 of 7819
          id: cord-321718-nzxvbj8b
      author: Khan, Moien AB.
       title: “Covibesity,” a new pandemic
        date: 2020-07-21
       words: 621
      flesch: 44
     summary: Lockdown is the world's biggest psychological experiment -and we will pay the 142 price Obesity and weight management in the elderly A 150 prospective study of holiday weight gain Selected health 152 behaviors that influence college freshman weight change Even transient rapid infancy weight gain is 155 associated with higher BMI in young adults and earlier menarche Risks associated with obesity 158 in pregnancy, for the mother and baby: a systematic review of reviews COVID 19 related home confinement in adults: weight gain 161 risks and opportunities The Relationship Between Feasting Periods 163 and Weight Gain: a Systematic Scoping Review Screen time for children and adolescents 165 during the COVID-19 pandemic. The impromptu nature of such 63 lockdown has triggered rapid weight gain, or covibesity.
    keywords: covid-19; weight
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        item: #5219 of 7819
          id: cord-321747-u2v1w99n
      author: Korytkowski, Mary
       title: A Pragmatic Approach to Inpatient Diabetes Management during the COVID-19 Pandemic
        date: 2020-06-04
       words: 3806
      flesch: 39
     summary: In the event of abrupt discontinuation of enteral nutrition in insulin treated patients, a 10% dextrose infusion administered at the same rate is recommended for the duration of the longest acting insulin administered prior to discontinuation (Reference 6). This emerging data for use of non-insulin therapies in the hospital setting will be addressed here in reference to COVID-19 patients (Table 1 ).
    keywords: care; covid-19; diabetes; insulin; management; patients
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        item: #5220 of 7819
          id: cord-321768-oevswvvd
      author: Duan, Ya-qi
       title: Deficiency of Tfh Cells and Germinal Center in Deceased COVID-19 Patients
        date: 2020-08-07
       words: 2311
      flesch: 44
     summary: We found a dominant presence of macrophages and a general deficiency of T cells and B cells in the lung tissues from deceased COVID-19 patients. In summary, our data highlight a defect of germinal center structure in deceased COVID-19 patients leading to an impaired humoral immunity.
    keywords: cells; covid-19; lung; patients; tissues
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        item: #5221 of 7819
          id: cord-321770-g5xcfhnh
      author: de Farias, Emmerson Carlos Franco
       title: MULTISYSTEM INFLAMMATORY SYNDROME IN A CHILD ASSOCIATED WITH CORONAVIRUS DISEASE 19 IN THE BRAZILIAN AMAZON: FATAL OUTCOME IN AN INFANT
        date: 2020-08-26
       words: 2340
      flesch: 35
     summary: Recently, there have been reports of children with severe inflammatory syndrome and multiorgan dysfunction associated with elevated inflammatory markers. Recently, there have been reports 4-7 of children who were previously healthy and tested positive for SARS-CoV-2, progressing to severe inflammatory syndrome and presenting with characteristics that are similar to those of Kawasaki disease or toxic shock syndrome.
    keywords: children; cov-2; covid-19; disease; pediatric; sars; syndrome
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        item: #5222 of 7819
          id: cord-321784-nubu5fuz
      author: Salazar, E.
       title: Treatment of COVID-19 Patients with Convalescent Plasma in Houston, Texas
        date: 2020-05-13
       words: 3568
      flesch: 54
     summary: Retrospective comparison of convalescent plasma with continuing high-dose methylprednisolone treatment in SARS patients Use of convalescent plasma therapy in SARS patients in Hong Kong Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2 Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Global initiative on sharing all influenza data -from vision to reality Convalescent plasma as a potential therapy for COVID The effectiveness of convalescent etiology: a systematic review and exploratory meta-analysis Clinical characteristics of fatal and recovered cases of Effective treatment of severe COVID-19 patients with tocilizumab GS-5734™) in Participants With Severe Coronavirus Disease (COVID-19) National Institutes of Health. https://doi.org/10.1101/2020.05.08.20095471 doi: medRxiv preprint A confounding variable in many convalescent plasma studies is the addition of other treatment regimens, such as antivirals and anti-inflammatory compounds.
    keywords: convalescent; covid-19; medrxiv; patients; plasma; preprint; sars; transfusion
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        item: #5223 of 7819
          id: cord-321787-6k4c6zei
      author: Rogo, Tanya
       title: Systemic Inflammation With Cardiac Involvement in Pediatric Patients With Evidence of COVID-19 in a Community Hospital in the Bronx, New York
        date: 2020-07-20
       words: 572
      flesch: 33
     summary: These cases highlight the challenge for physicians assessing pediatric patients presenting with symptoms of fever and gastrointestinal illness. In addition to the standard differential diagnoses of bacterial sepsis, gastroenteritis, and acute abdomen, multisystem inflammatory syndrome with myocardial involvement must also be considered, even with negative SARS-CoV-2 PCR results.
    keywords: covid-19; patients
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        item: #5224 of 7819
          id: cord-321816-ipbwpw26
      author: Fawad, Muhammad
       title: Simple ideas to mitigate the impacts of the COVID-19 epidemic on refugees with chronic diseases
        date: 2020-05-06
       words: 772
      flesch: 34
     summary: As clinical care is resumed, it is important to think about how to use community health volunteers to mitigate the impact of COVID-19 in this population. Second, community health volunteers could provide refugees with a trusted connection to surveillance systems, risk communication, and the epidemic response, which is a major aim of community engagement [5] .
    keywords: care; covid-19; health
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        item: #5225 of 7819
          id: cord-321846-pzmewp2r
      author: Alvarado, Amado
       title: COVID-19 associated with onset nephrotic syndrome in a pediatric patient: coincidence or related conditions?
        date: 2020-08-27
       words: 1074
      flesch: 36
     summary: CASE-DIAGNOSIS: We present a 15-year-old boy who tested positive for SARS-COV-2 infection and onset of nephrotic syndrome, without antecedent of kidney disease and who had normal urine tests shortly before being affected by COVID-19. key: cord-321846-pzmewp2r authors: Alvarado, Amado; Franceschi, Gabriela; Resplandor, Evelin; Sumba, Jeannethe; Orta, Nelson title: COVID-19 associated with onset nephrotic syndrome in a pediatric patient: coincidence or related conditions? date: 2020-08-27 journal:
    keywords: covid-19; kidney; syndrome
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        item: #5226 of 7819
          id: cord-321852-e7369brf
      author: Wang, Bo
       title: AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system
        date: 2020-11-10
       words: 6473
      flesch: 48
     summary: COVID-19 CT segmentation dataset [17] is also a publicly available dataset. In addition, training AI models requires a lot of samples.
    keywords: classification; covid-19; data; diagnosis; images; lung; model; net; patients; segmentation; system
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        item: #5227 of 7819
          id: cord-321865-cn9dm6ju
      author: Anca, Diana
       title: Electrophysiology Practice during the COVID-19 Pandemic: A New York Tertiary Hospital Experience
        date: 2020-10-29
       words: 2984
      flesch: 32
     summary: The HRS/ACC/AHA recommendation to postpone or cancel non-urgent procedures was based upon federal and state executive orders and the strain on hospital systems who were diverting all resources to care for COVID-19 patients. Fortunately, the EP laboratory is located within the Catheterization Suite, which enabled creation of a procedure room that would serve COVID-19 patients for both EP and coronary catheterization procedures.
    keywords: care; covid-19; hrs; management; patients; procedures; room
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        item: #5228 of 7819
          id: cord-321867-7n88rl6p
      author: Jee, J.
       title: Oncologic Immunomodulatory Agents in Patients with Cancer and COVID-19
        date: 2020-08-12
       words: 3946
      flesch: 45
     summary: [6] [7] have identified cancer patient characteristics, such as thoracic and hematologic malignancy, associated with worse outcomes, but there is mixed data regarding the outcomes of cancer patients with COVID-19 treated with immunomodulatory agents. In the absence of prospective studies and evidence-based guidelines, our data may aid providers looking to assess the risks and benefits of these agents in caring for cancer patients in the COVID-19 era.
    keywords: cancer; covid-19; medrxiv; outcomes; patients; preprint
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        item: #5229 of 7819
          id: cord-321873-9l9zp6gm
      author: Zhou, Bo
       title: The duration of viral shedding of discharged patients with severe COVID-19
        date: 2020-04-17
       words: 608
      flesch: 49
     summary: The study was limited to a small number of discharged patients with severe COVID-19, not including mild or moderate infection, because we enrolled patients from the designated hospital for severe COVID-19. c e p t e d M a n u s c r i p t Clinical features of patients infected with 2019 novel coronavirus in Wuhan Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical Characteristics of 138 Hospitalized Patients With Novel Coronavirus-Infected Pneumonia in Wuhan New coronavirus pneumonia prevention and control program Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Positive RT-PCR Test Results in Patients Recovered From COVID-19 A c c
    keywords: patients
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        item: #5230 of 7819
          id: cord-321878-bnjupaik
      author: Deliwala, Smit S.
       title: A 29-Year-Old Male with a Fatal Case of COVID-19 Acute Respiratory Distress Syndrome (CARDS) and Ventilator-Induced Lung Injury (VILI)
        date: 2020-07-23
       words: 2254
      flesch: 38
     summary: COVID-19 patients complicated by ARDS (CARDS) can present despite lacking traditional risk factors such as advancing age, pre-existing co-morbidities, or an advanced lung pathology [5] . Post-mortem studies reveal numerous thromboses in COVID-19 patients with d-dimer serving as a surrogate marker of pulmonary endothelial damage, promoting ventilation-perfusion mismatches and subsequent hypoxemia
    keywords: ards; covid-19; lung; patients; pneumothorax; type; vili
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        item: #5231 of 7819
          id: cord-321960-p4twpm2z
      author: Thibaudin, Marion
       title: Immunological features of coronavirus disease 2019 in patients with cancer
        date: 2020-09-07
       words: 3167
      flesch: 42
     summary: When looking at the proportion of myeloid cells, we observed no difference in the proportion of monocytes, but a marked increase in the proportion of neutrophils in cancer patients, with a higher proportion in COVID-19 positive cancer patients ( Figure 3A ). Compared with non COVID-19 cancer patients, COVID-19 positive cancer patients had more extensive lymphopenia and hypoalbuminemia, with higher levels of C-reactive protein.
    keywords: cancer; cd8; cells; covid-19; figure; patients; positive; sars
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        item: #5232 of 7819
          id: cord-321976-ao3bg8xi
      author: Robinson, Philip C
       title: Management of autoimmune disease during the COVID-19 pandemic
        date: 2020-08-18
       words: 1020
      flesch: 41
     summary: So far there has not been any increase in the risk of hospitalisation for COVID-19 in rheumatic disease patients taking disease-modifying antirheumatic drugs alone (e.g. methotrexate) or in combination with biologics or Janus kinase inhibitors, compared to patients who were not taking these drugs. However, patients with rheumatic disease were more likely to require intensive care or ventilation.
    keywords: covid-19; disease; patients
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        item: #5233 of 7819
          id: cord-321983-566pbuic
      author: Liu, Wei
       title: Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease
        date: 2020-02-28
       words: 3809
      flesch: 41
     summary: We investigated factors affecting the outcomes of COVID-19 patients to evaluate the prognosis and further improve the treatment of patients with COVID-19 associated pneumonia with the hope of reducing mortality. This study aims to investigate the factors affecting the progression of pneumonia in COVID-19 patients.
    keywords: anti; covid-19; group; patients; pneumonia; progression
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        item: #5234 of 7819
          id: cord-321984-qjfkvu6n
      author: Tang, Lu
       title: A Review of Multi‐Compartment Infectious Disease Models
        date: 2020-08-03
       words: 21860
      flesch: 43
     summary: Building sampling variations in infectious disease models makes a statistical modelling approach different from a mathematical modelling approach. Hence, statistical extensions are necessary to incorporate sampling uncertainty in estimation and inference for infectious disease models.
    keywords: .t/; analysis; compartment; covid-19; data; disease; dynamics; e.g.; epidemic; estimation; example; function; individuals; infection; model; modelling; number; population; prediction; rate; section; sir model; state; surveillance; system; time; time t; transmission
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        item: #5235 of 7819
          id: cord-321990-z83c4e47
      author: Ravioli, Svenja
       title: COVID-19 screening in outpatients with risk factors and healthcare workers
        date: 2020-07-17
       words: 312
      flesch: 59
     summary: The highest rate of positive test results was noticed on 30 March with 21% positive results (see Fig. 1 ). After screening, all persons were initially managed as outpatients, 7 persons with positive test results, 1 HCW and 6 PRFs, needed hospitalization during the course of the disease (0.92%), 6 recovered well, while 1 person is still critically ill and requires intensive care treatment and mechanical ventilation.
    keywords: prfs
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        item: #5236 of 7819
          id: cord-322009-0cwljo0c
      author: Ma, Ling
       title: Coinfection of SARS-CoV-2 and Other Respiratory Pathogens
        date: 2020-08-26
       words: 3797
      flesch: 36
     summary: To differentiate between respiratory infections caused by SARS-CoV-2 and other respiratory pathogens during the COVID-19 outbreak in Wuhan, we simultaneously tested for SARS-CoV-2 and pathogens associated with CAP to determine the incidence and impact of respiratory coinfections in COVID-19 patients. Coinfections in COVID-19 patients are common.
    keywords: coinfection; cov-2; covid-19; group; pathogens; patients; sars; study
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        item: #5237 of 7819
          id: cord-322034-8wwqxkjl
      author: Ma, Ke
       title: From the perspective of Traditional Chinese Medicine: treatment of mental disorders in COVID-19 survivors
        date: 2020-09-30
       words: 5229
      flesch: 40
     summary: on the depressive behaviors of vascular depression mice and brain tissue pathology Clinical Effect of Modified Suanzaoren Decoction on Extensive Anxiety Disorder Suanzaoren Decoction for Cancer Patients with Anxiety Disorder Effects of Suanzaoren Decoction on Serum NO and the Level of Cytokines in Rats Clinical observation on 30 cases of generalized anxiety disorder treated by modified Huanglian Ejiao Decoction Clinical observation on treating 60 cases of anxiety disorder patients with the Huanglian Ejiao decoction plus fluvoxamine 50 Cases of Anxiety Disorder Treated with Gardenia and Soy Decoction Effect of suanzaoren decoction combined with zhizichi decoction on anxiety insomnia Clinical study on suanzaoren decoction combined with Zhizichi Decoction in treating anxiety insomnia Effect of Huanglian E jiao Decoction on Anxiety Rat Model of Elevated 10-puzzle Palace Generalized anxiety disorder: neurobiological and pharmacotherapeutic perspectives Anxiolytic-like effects of sanjoinine A isolated from Zizyphi Spinosi Semen: possible involvement of GABAergic transmission Correlation Between Component Compatibilities of Suanzaoren Decoction and Their Effects of Anti-anxiety Anxiolytic effect of berberine on exploratory activity of the mouse in two experimental anxiety models: interaction with drugs acting at 5-HT receptors Anxiolytic effect of wogonin, a benzodiazepine receptor ligand isolated from Scutellaria baicalensis Georgi Anxiolytic-like effects of baicalein and baicalin in the Vogel conflict test in mice Anxiolytic effect of Gardeniae Fructus-extract containing active ingredient from Kamishoyosan (KSS), a Japanese traditional Kampo medicine The Relationship of Posttraumatic Stress Disorder with Childhood Traumas, Personality Characteristics, Depression and Anxiety Symptoms in Patients with Diagnosis of Mixed Anxiety-Depression Disorder Present situation of pharmacological research on anti-anxiety of traditional Chinese medicine Effect of Baihe Dihuang Decoction on 5-HT Level in hippocampus of rats with Post-traumatic Stress Disorder Effects of Baihe Dihuang Decoction on Behavior and GR /MR Expression in Hippocampus of Rats with Post Traumatic Stress Disorder Study on mechanism of Guilu Erxianjiao in treatment of post-traumatic stress disorder based on network pharmacology Effect of Guilu Erxian Gum on Negative Feedback Function of HPA Axis in Rats with Post-traumatic Stress Disorder and Its Mechanism Effect of Guilu Erxian Glue on Behavior and Expression of GR and 5-HT Receptor in Hippocampus of Rats with Posttraumatic Stress Disorder Protective effects of lycium barbarum polysaccharide on depression rats with post-traumatic stress disorder The anxiolytic-like effects of ginsenoside Rg2 on an animal model of PTSD nourishing Yin of heart and calming mind Furthermore, Lily Bulb and Rehmannia Decoction was able to alleviate the symptoms of depression patients with Yin deficiency and internal heat syndrome remarkably and long-term administration was not harmful [52] .
    keywords: anxiety; covid-19; decoction; depression; disorder; effect; lily; patients; ptsd; stress; symptoms; treatment
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        item: #5238 of 7819
          id: cord-322054-whjisspt
      author: Zhang, S.
       title: Concerns about disease management and psychological stress in SAPHO patients during the COVID-19 epidemic
        date: 2020-05-11
       words: 3485
      flesch: 48
     summary: As a group affected by the epidemic prevention and control measures, chronic disease patients are classified as level 4 population together with susceptible people and the public. However, considering the double impact of the epidemic on the physical and mental health of chronic disease patients, it is suggested that more attention should be paid to their psychological and medical care.
    keywords: covid-19; disease; epidemic; patients; preprint; sapho; syndrome
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        item: #5239 of 7819
          id: cord-322063-96suqyfg
      author: Kampmeier, Stefanie
       title: A nosocomial cluster of vancomycin resistant enterococci among COVID-19 patients in an intensive care unit
        date: 2020-09-22
       words: 2413
      flesch: 35
     summary: In recent years, the incidence of VRE infections has increased worldwide, including in Germany [11] . VRE infections are associated with significant mortality, in particular in patients with multiple co-morbidities and
    keywords: cluster; control; covid-19; infection; patients; samples; vancomycin; vre
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        item: #5240 of 7819
          id: cord-322079-87iqc21s
      author: Agostiniani, Rino
       title: Providing pediatric well-care and sick visits in the COVID-19 pandemic era: the recommendations of the Italian pediatric society
        date: 2020-09-16
       words: 1717
      flesch: 43
     summary: In case of sick children, the Italian Pediatric Society recommends to identify those with signs or symptoms compatible with COVID-19 and: schedule different appointments, separated from COVID 19 unrelated flu like patients. Pediatricians have observed a significant decrease in inperson child health visits during the COVID-19 pandemic, which puts children's health at risk.
    keywords: cases; children; covid-19; health; visits
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        item: #5241 of 7819
          id: cord-322087-gj5mfzxz
      author: de Sanctis, Vincenzo
       title: Coronavirus Disease 2019 (COVID-19) in adolescents: An update on current clinical and diagnostic characteristics
        date: 2020-05-11
       words: 4598
      flesch: 42
     summary: Detailed epidemiological information based on a larger sample of COVID-19 patients is needed to determine the infectious period of SARS-CoV-2, as well as whether transmission can occur from asymptomatic individuals during the incubation period (pre-symptomatic period). In summary, compared with elderly patients, adolescent and young adult COVID-19 patients have a longer incubation period, a shorter serial interval, higher odds of being asymptomatic and a lower mortality rate.
    keywords: adolescents; cases; children; coronavirus; cov-2; covid-19; disease; infection; patients; sars; transmission
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        item: #5242 of 7819
          id: cord-322099-mb17dnf2
      author: Shanahan, Lilly
       title: Emotional distress in young adults during the COVID-19 pandemic: evidence of risk and resilience from a longitudinal cohort study
        date: 2020-06-23
       words: 5554
      flesch: 36
     summary: In addition, pre-pandemic social stressors (e.g. bullying victimization, stressful life events, and feelings of social exclusion) predicted during-pandemic emotional distress. Longitudinal data are also needed to examine (1) the roles of previous distress and stressors in emotional distress during the pandemic and (2) how COVID-19-related stressors and coping strategies are associated with emotional distress when pre-pandemic distress is accounted for.
    keywords: adults; covid-19; distress; health; lockdown; pandemic; participants; pre; risk; stressors; symptoms
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        item: #5243 of 7819
          id: cord-322102-4fi0y96f
      author: Zimmermann, Matthias
       title: Approaches to the management of patients in oral and maxillofacial surgery during COVID-19 pandemic
        date: 2020-04-04
       words: 4695
      flesch: 44
     summary: When surgery is performed on COVID-19 patients, adequate personal protective equipment is crucial. In order to save resources and to avoid unnecessary exposure to infected patients, there is the need to schedule interventions depending on their priority.
    keywords: cov-2; covid-19; infection; patients; sars; surgery; transmission
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        item: #5244 of 7819
          id: cord-322110-crt3h6ua
      author: Arcari, Luca
       title: Incidence and determinants of high-sensitivity troponin and natriuretic peptides elevation at admission in hospitalized COVID-19 pneumonia patients
        date: 2020-09-28
       words: 3489
      flesch: 37
     summary: EACVI recommendations on precautions, indications, prioritization, and protection for patients and healthcare personnel Reporting of D-dimer data in COVID-19: some confusion and potential for misinformation ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure Platelet function analyzer 100 and brain natriuretic peptide as biomarkers in obstructive hypertrophic cardiomyopathy Prognostic value of interleukin-6, C-reactive protein, and procalcitonin in patients with COVID-19 Suspected myocardial injury in patients with COVID-19: evidence from front-line clinical observation in Wuhan, China Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial Acute respiratory distress syndrome: the Berlin definition Early outcomes with utilization of tissue plasminogen activator in COVID-19 associated respiratory distress: a series of five cases Benefits and risks of the P/F approach Acute pulmonary embolism in COVID-19 patients on CT angiography and relationship to D-Dimer levels Cardiovascular manifestations and treatment considerations in covid-19 COVID-19: the crucial role of blood coagulation and fibrinolysis Endothelial cell infection and endotheliitis in COVID-19 Disseminated intravascular coagulation Description and Proposed Management of the Acute Histopathological findings and viral tropism in UK patients with severe fatal COVID-19: a post-mortem study Compassionate use of Remdesivir for patients with severe Covid-19 COVID-19 outbreak: an update on therapeutic options COVID-19 pneumonia: different respiratory treatment for different phenotypes ? Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Risk factors for intensive care unit admission and in-hospital mortality among hospitalized adults identified through the U.S. coronavirus disease 2019 (COVID-19)-associated hospitalization surveillance network (COVID-NET) Clinical care within these units, recently established in order to provide dedicated assistance to COVID-19 patients, was managed by full-time dedicated internal medicine or cardiology specialists.
    keywords: covid-19; dimer; patients; pneumonia; troponin
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        item: #5245 of 7819
          id: cord-322142-y7v8tcnb
      author: Kapoor, Indu
       title: Transference of COVID-19 patient in hospitals – A crucial phase
        date: 2020-05-26
       words: 560
      flesch: 45
     summary: key: cord-322142-y7v8tcnb authors: Kapoor, Indu; Prabhakar, Hemanshu; Mahajan, Charu title: Transference of COVID-19 patient in hospitals – A crucial phase date: 2020-05-26 journal: J Clin Anesth DOI: 10.1016/j.jclinane.2020.109931 sha: doc_id: 322142 cord_uid: y7v8tcnb • COVID-19 virus is primarily transmitted between humans through respiratory droplets and contact routes. • Transportation of COVID-19 patient carries very high transmission risk to personals involved.
    keywords: covid-19; patient
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        item: #5246 of 7819
          id: cord-322159-3anst3os
      author: Kiaghadi, A.
       title: Assessing COVID-19 Risk, Vulnerability and Infection Prevalence in Communities
        date: 2020-05-08
       words: 3427
      flesch: 45
     summary: The copyright holder for this preprint (which this version posted May 8, 2020. 7) , B) Morbidity rates in Harris County census tracts based on a worst-case scenario using NYC data [49] , C) Fig S16. We also used reported rates for morbidity, hospitalization, and mortality in other regions to estimate risk at the county (Harris County) and census tract levels.
    keywords: author; county; covid-19; funder; medrxiv; perpetuity; preprint; vulnerability
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        item: #5247 of 7819
          id: cord-322205-vui1jh2v
      author: None
       title: Images from the Frontlines of the COVID-19 Pandemic
        date: 2020-08-17
       words: 113
      flesch: 72
     summary: Top row, left to right: self-portrait of Carlos Borba All India Institute of Medical Science key: cord-322205-vui1jh2v authors: nan title: Images from the Frontlines of the COVID-19 Pandemic date: 2020-08-17 journal: Anesthesiology DOI: 10.1097/aln.0000000000003513 sha: doc_id: 322205 cord_uid: vui1jh2v nan Staff nurse Natasha Singh sits on a bench outside a COVID-19 ward.
    keywords: vui1jh2v
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        item: #5248 of 7819
          id: cord-322229-a7sz6e3c
      author: Suryadevara, V.
       title: Mental Health Status among the South Indian Pharmacy Students during Covid-19 Pandemic Quarantine Period: A Cross-Sectional Study
        date: 2020-05-12
       words: 2264
      flesch: 49
     summary: The study findings shows the need of conducting more such studies and can be used to prepare appropriate psychological interventions to improve mental health among the young public during the pandemic. The study findings can be used to prepare psychological interventions to improvemental health among the young public during the COVID-19 epidemic.
    keywords: covid-19; health; outbreak; preprint; stress
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        item: #5249 of 7819
          id: cord-322233-1i6zj9b3
      author: Khurana, Sonal
       title: Now is the time to press the reset button: Helping India’s companies to become more resilient and effective in overcoming the impacts of COVID-19, climate changes and other crises
        date: 2020-10-01
       words: 9072
      flesch: 46
     summary: The main objective of the authors of this paper was to develop a holistic view of sustainable supply chains. Supply-chain recovery in coronavirus times-plan for now and the future Stepping up and stepping out of COVID-19: New challenges for environmental sustainability policies in the global airline industry 2019-nCoV epidemic: address mental health care to empower society COVID-19, extractive industries, and indigenous communities in Canada: Notes towards a political economy research agenda Analytical hierarchy process-based framework for VMI adoption Incorporating social aspects in sustainable supply chains: Trends and future directions
    keywords: ahp; chains; covid-19; covid-19 pandemic; experts; factors; future; health; help; india; industries; pandemic; research; supply
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        item: #5250 of 7819
          id: cord-322244-3en3yey1
      author: Nkengasong, John N
       title: Looming threat of COVID-19 infection in Africa: act collectively, and fast
        date: 2020-02-27
       words: 1271
      flesch: 39
     summary: Because mitigating the potential spread of COVID-19 in Africa will require rapid detection and containment, the laboratory work streams of AFTCOR, Africa CDC, and WHO are working closely to expeditiously scale up diagnostic testing capacity linked to enhanced surveillance and monitoring-eg, at the beginning of February, only two countries in Africa had the diagnostic capacity to test for COVID-19. Lastly, the capacity-building training efforts that Africa CDC and WHO are conducting must be implemented and cascaded immediately down the health system pyramid in each country.
    keywords: africa; countries; covid-19; risk
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        item: #5251 of 7819
          id: cord-322256-mv9ll0h4
      author: Edelman, E. Jennifer
       title: Confronting Another Pandemic: Lessons from HIV can Inform Our COVID-19 Response
        date: 2020-05-12
       words: 1750
      flesch: 33
     summary: Further, COVID-19 care can be informed by extensive efforts that have been applied to enhance retention in lifelong HIV care and outreach efforts to identify and connect with patients vulnerable to effects of social isolation, worsening mental health, substance use, and intimate partner violence. With both HIV and COVID-19, the risk of occupational exposure and the safety of health care workers has been a paramount concern.
    keywords: care; covid-19; health; hiv
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        item: #5252 of 7819
          id: cord-322258-rl9o60cs
      author: Parmar, Chetan
       title: Bariatric and Metabolic Surgery Can Prevent People with Obesity from COVID-19 Infection
        date: 2020-07-15
       words: 1057
      flesch: 55
     summary: Patients with BMS surgery are not at increased risk of COVID-19 infection compared with the general population. Published literature shows that the predictors of poor outcomes in COVID-19 infection are obesity, hypertension (HT), and type 2 diabetes (T2DM)
    keywords: bms; covid-19; obesity; patients
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        item: #5253 of 7819
          id: cord-322259-khknne8s
      author: de Roquetaillade, C.
       title: Unusual arterial thrombotic events in Covid-19 patients
        date: 2020-09-10
       words: 1320
      flesch: 41
     summary: Arterial thrombotic events included acute coronary occlusions (n = 9), stroke (n = 6), limb ischemia (n = 3), splenic infarcts (n = 3), aortic thrombosis (n = 2) and occlusive mesenteric ischemia (n = 1). Reported arterial thrombotic events were acute coronary occlusions (n=9), stroke (n=6), limb ischemia (n=3), splenic infarcts (n=3), aortic thrombosis (n=2) activity tested in 2 patients was normal.
    keywords: arterial; covid-19; events; patients
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        item: #5254 of 7819
          id: cord-322267-pbj819vk
      author: Gautam, Sneha
       title: COVID-19: air pollution remains low as people stay at home
        date: 2020-05-21
       words: 1291
      flesch: 44
     summary: The National Aeronautics and Space Administration (NASA) and European Space Agency (ESA) released air pollution data for Asian and European countries to assess the significant changes in air quality. The ESA collects air quality data by using TROPOMI instruments using Sentinel -5P satellite during COVID-19 lockdowns.
    keywords: air; covid-19
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        item: #5255 of 7819
          id: cord-322279-6ffnejwj
      author: Kwon, Seungwon
       title: Could herbal medicine (Soshihotang) be a new treatment option for COVID-19?: A Narrative Review
        date: 2020-07-17
       words: 4612
      flesch: 41
     summary: Based on this guideline, herbal medicine treatment has been used in more than 50% of confirmed patients with COVID-19 in J o u r n a l P r e -p r o o The search keywords included SSHT, constituents of SSHT, and antiviral effect.
    keywords: covid-19; disease; effect; hepatitis; liver; medicine; patients; ssht; symptoms; treatment; virus
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        item: #5256 of 7819
          id: cord-322290-zx3i8mpo
      author: Yelin, Dana
       title: Long-term consequences of COVID-19: research needs
        date: 2020-09-01
       words: 928
      flesch: 46
     summary: key: cord-322290-zx3i8mpo authors: Yelin, Dana; Wirtheim, Eytan; Vetter, Pauline; Kalil, Andre C; Bruchfeld, Judith; Runold, Michael; Guaraldi, Giovanni; Mussini, Cristina; Gudiol, Carlota; Pujol, Miquel; Bandera, Alessandra; Scudeller, Luigia; Paul, Mical; Kaiser, Laurent; Leibovici, Leonard title: Long-term consequences of COVID-19: research needs date: 2020-09-01 journal: Lancet Infect Dis DOI: 10.1016/s1473-3099(20)30701-5 sha: doc_id: 322290 cord_uid: zx3i8mpo nan Weeks and months after the onset of acute COVID-19, people continue to suffer. For efficient research and for research that our patients (and we) can trust, some common problems in the description and research of acute COVID-19 should be avoided.
    keywords: acute; covid-19; patients
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        item: #5257 of 7819
          id: cord-322296-8j4xw3vp
      author: Passamonti, Serena Maria
       title: Solid organ transplantation in the Coronavirus disease 2019 (COVID-19) Era: “The great bet” in the North Italy Transplant program (NITp) area
        date: 2020-07-07
       words: 1517
      flesch: 45
     summary: The first outcome was the cumulative incidence of COVID-19 in transplanted patients and COVID-19 related mortality. [9] [10] [11] This difference could be In addition, general characteristics of transplanted patients developing COVID-19 did not differ from COVID-19 positive general population, 4 supporting the hypothesis that transplant per se seemed to be not a risk-factor for the infection.
    keywords: covid-19; mortality; patients; recipients
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        item: #5258 of 7819
          id: cord-322313-bq1g5g6p
      author: Kamishima, Tamotsu
       title: Editorial for “Clinical Potential of UTE‐MRI for Assessing the COVID‐19: Patient‐ and Lesion‐Based Comparative Analysis”
        date: 2020-07-11
       words: 1118
      flesch: 36
     summary: Due to the rapid spread and increasing number of COVID-19 cases caused by a new coronavirus-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the rapid and accurate detection of the virus and/or the disease is increasingly vital for controlling the sources of infection and for preventing progression of the illness in patients. Accordingly, the Fleischner Society published a multinational consensus statement regarding the role of CT chest imaging for the management of patients during the COVID-19 pandemic, in three different scenarios 7 : 1) Imaging is not indicated in patients with suspected COVID-19 and mild clinical features unless they are at risk for disease progression; 2) Imaging is indicated in a patient with COVID-19 and worsening respiratory status; 3) In a resourceconstrained environment, imaging is indicated for medical triage of patients with suspected COVID-19 who present with moderatesevere clinical features and a high pretest probability of disease.
    keywords: covid-19; mri; patients
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        item: #5259 of 7819
          id: cord-322322-woz6lwdu
      author: Marcum, Michelle
       title: COVID‐19 pandemic and impact on cancer clinical trials: An academic medical center perspective
        date: 2020-07-10
       words: 3156
      flesch: 37
     summary: key: cord-322322-woz6lwdu authors: Marcum, Michelle; Kurtzweil, Nicky; Vollmer, Christine; Schmid, Lisa; Vollmer, Ashley; Kastl, Alison; Acker, Kelly; Gulati, Shuchi; Grover, Punita; Herzog, Thomas J.; Ahmad, Syed A.; Sohal, Davendra; Wise‐Draper, Trisha M. title: COVID‐19 pandemic and impact on cancer clinical trials: An academic medical center perspective date: 2020-07-10 journal: Cancer Med DOI: 10.1002/cam4.3292 sha: doc_id: 322322 cord_uid: woz6lwdu The COVID‐19 pandemic changed health‐care operations around the world and has interrupted standard clinical practices as well as created clinical research challenges for cancer patients. In addition, the decision whether to continue cancer clinical trials became a safety concern regarding the treatment effect on cancer patients' vulnerability for COVID-19 contraction, potential viral exposure risk to clinical trial staff, and potential impact of an infected clinical trial cancer patient on study outcomes.
    keywords: cancer; covid-19; pandemic; patients; research; risk; study; treatment; trials
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        item: #5260 of 7819
          id: cord-322332-0pi3wcv5
      author: Conforti, Claudio
       title: Doxycycline, a widely used antibiotic in dermatology with a possible anti‐inflammatory action against IL‐6 in COVID‐19 outbreak
        date: 2020-05-15
       words: 511
      flesch: 28
     summary: In fact, in addition to its well-defined antibiotic effects (bacteriostatic action by inhibition of bacterial protein synthesis), in vitro studies have shown doxycycline to exert anti-inflammatory effects at low (20-40 mg/day) and high (100 or 200 mg/day) doses with inhibitory action on metalloproteases and modulating effects of pro-inflammatory cytokines IL-6, IL-8, and tumor necrosis factor-alpha. Thereby, low doxycycline doses have been shown to be more effective than high doses to prevent induction of pro-inflammatory cytokines (such as IL-6) in inflammatory diseases.
    keywords: covid-19; doxycycline
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        item: #5261 of 7819
          id: cord-322336-ktxi3v3a
      author: Griffin, John H.
       title: COVID‐19 hypothesis: Activated protein C for therapy of virus‐induced pathologic thromboinflammation
        date: 2020-06-12
       words: 1711
      flesch: 23
     summary: John H. Griffin https://orcid.org/0000-0002-4302-2547 Clinical features of patients infected with 2019 novel coronavirus in Wuhan Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Coronavirus disease 2019 in elderly patients: Characteristics and prognostic factors based on 4-week follow-up Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Thrombosis as an intravascular effector of innate immunity Thromboinflammation: challenges of therapeutically targeting coagulation and other host defense mechanisms Thromboinflammation and vascular dysfunction Activated protein C: biased for translation Homeostatic effects of coagulation protease-dependent signaling and protease activated receptors The immunoregulatory activities of activated protein C in inflammatory disease Tissue factor at the crossroad of coagulation and cell signaling Regulation of immune cell signaling by activated protein C Cytoprotective activated protein C averts Nlrp3 inflammasome-induced ischemia-reperfusion injury via mTORC1 inhibition Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C Activated protein C targets CD8+ dendritic cells to reduce the mortality of endotoxemia in mice Cytoprotective-selective activated protein C attenuates Pseudomonas aeruginosa-induced lung injury in mice Barrierprotective effects of activated protein C in human alveolar epithelial cells Activated protein C attenuates ischemia-reperfusion-induced acute lung injury Activated protein C, protease activated receptor 1, and neuroprotection Phase 1 safety, tolerability and pharmacokinetics of 3K3A-APC in healthy adult volunteers Final results of the RHAPSODY trial: a multi-center, phase 2 trial using a continual reassessment method to determine the safety and tolerability of 3K3A-APC, a recombinant variant of human activated protein C, in combination with tissue plasminogen activator, mechanical thrombectomy or both in moderate to severe acute ischemic stroke key: cord-322336-ktxi3v3a authors: Griffin, John H.; Lyden, Patrick title: COVID‐19 hypothesis: Activated protein C for therapy of virus‐induced pathologic thromboinflammation date: 2020-06-12 journal:
    keywords: apc; covid-19; host; patients; protein
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        item: #5262 of 7819
          id: cord-322337-4xhwm3k4
      author: Desai, P. S.
       title: Sentiment Informed Timeseries Analyzing AI (SITALA) to curb the spread of COVID-19 in Houston
        date: 2020-07-24
       words: 1761
      flesch: 54
     summary: The present study introduces a new AI model, viz., Sentiment Informed Timeseries Analyzing AI (SITALA), that has been trained on COVID-19 test positivity data and news sentiment from over 2750 news articles for the Harris county. This study attempts to develop a multivariate artificial intelligence (AI) model to analyze timeseries of COVID-19 positivity and news sentiment.
    keywords: covid-19; news; preprint; sentiment
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        item: #5263 of 7819
          id: cord-322385-sc2vxxnn
      author: Ebinger, J.
       title: SARS-CoV-2 Seroprevalence Across a Diverse Cohort of Healthcare Workers
        date: 2020-08-04
       words: 3674
      flesch: 24
     summary: In conclusion, in a highly diverse population of healthcare workers, demographic factors associated with Covid-19 antibody positivity indicate potential factors outside of the workplace associated with SARS-CoV-2 exposure, although these do not appear related to the number of people or to the presence of children in the home. In multivariable-adjusted analyses of pre-existing characteristics (Figure 2 and Supplemental In multivariable-adjusted analyses of Covid-19 related exposures (Figure 3 and Supplemental In multivariable-adjusted analyses of Covid-19 response variables (Figure 4 and Supplemental Table 6 ), the strongest self-reported symptom associated with greater odds of seropositive status was anosmia (11.53 [7.51, 17.
    keywords: antibody; cov-2; covid-19; exposure; factors; sars; seroprevalence; study
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        item: #5264 of 7819
          id: cord-322386-fkmrzitm
      author: Duran, Emine
       title: Vital corner of diagnostic challenge: eosinophilic granulomatosis with polyangiitis or COVID-19 pneumonia?
        date: 2020-07-24
       words: 1601
      flesch: 42
     summary: Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 global rheumatology alliance physician-reported registry Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR False-negative results of initial RT-PCR assays for COVID-19: a systematic review Sensitivity of chest CT for COVID-19: comparison to RT-PCR Temporal changes of CT findings in 90 patients with COVID-19 pneumonia: a longitudinal study Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study CT imaging features of 2019 novel coronavirus (2019-nCoV) Eosinophil responses during COVID-19 infections and coronavirus vaccination Eosinophilic granulomatosis with polyangiitis (Churg-Strauss) Anti-neutrophil cytoplasmic autoantibodies: methodological aspects and clinical significance in systemic vasculitis Eosinophilic granulomatosis with polyangiitis mimicking coronavirus disease 2019: a case report COVID-19 pneumonia: a review of typical CT findings and differential diagnosis The American College of rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis) OP0021 draft classification criteria for the anca associated vasculitides A systematic review of the accuracy of COVID-19 tests reported false-negative rates up to 29% (equating to a sensitivity of 71-98%), based on negative RT-PCR tests which could turn out positive on repeated testing.
    keywords: asthma; covid-19; patients; pneumonia
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        item: #5265 of 7819
          id: cord-322404-lj5hfuqm
      author: Halvatsiotis, P.
       title: Demographic and Clinical Features of Critically Ill Patients with COVID-19 in Greece: The Burden of Diabetes and Obesity
        date: 2020-07-17
       words: 2735
      flesch: 47
     summary: Undoubtedly, diabetes mellitus is now recognized as one of the most common commorbidities in Covid-19 patients [14] and since many diabetic patients are obese this leads to a twofold increase in the incidence of requiring intensive care Results The median age of the patients was 65.5 (IQR 56-73), majority were male (80%) and obesity was present in 34.4% of patients most prevalent to younger than 55 years.
    keywords: covid-19; diabetes; iqr; obesity; patients; study
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        item: #5266 of 7819
          id: cord-322414-dpx191xh
      author: Harke, Nina N.
       title: To defer or not to defer? A German longitudinal multicentric assessment of clinical practice in urology during the COVID-19 pandemic
        date: 2020-09-15
       words: 3778
      flesch: 39
     summary: This disadvantageous postoperative course for COVID-19 positive patients was also supported by Nepogodiev [13] . Accordingly, only a minority of the respondents reported COVID-19 positive patients in their departments in March and April.
    keywords: april; cases; covid-19; march; patients; surgeries; surgery; week
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        item: #5267 of 7819
          id: cord-322417-9e95m4kz
      author: Segovia-Juarez, Jose
       title: High altitude reduces infection rate of COVID-19 but not case-fatality rate
        date: 2020-07-15
       words: 1257
      flesch: 50
     summary: key: cord-322417-9e95m4kz authors: Segovia-Juarez, Jose; Castagnetto, Jesús M.; Gonzales, Gustavo F. title: High altitude reduces infection rate of COVID-19 but not case-fatality rate date: 2020-07-15 journal: It is suggested that life at high altitude may reduce COVID infections and case-fatality rates (cases/deaths).
    keywords: altitude; case; covid-19; fatality
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        item: #5268 of 7819
          id: cord-322427-6hsdlogg
      author: Holten, Aleksander Rygh
       title: Predicting severe COVID-19 in the Emergency Department
        date: 2020-10-21
       words: 3516
      flesch: 48
     summary: NEWS2 may be a useful screening tool in evaluating COVID-19 patients during hospital admission. NEWS2 may be a useful screening tool in evaluating COVID-19 patients during hospital admission.
    keywords: covid-19; disease; news2; patients; pneumonia; points; qsofa; score
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        item: #5269 of 7819
          id: cord-322439-86dojc70
      author: Celarier, Thomas
       title: Covid-19: Adapting the geriatric organisations to respond to the pandemic
        date: 2020-06-11
       words: 1396
      flesch: 42
     summary: Also, deaths in nursing homes account for almost 40% of all deaths (1), while nursing homes residents represent only 1% of the French population (2) . Associated with this new organization, mobile teams propose medical care to nursing home patients at their places of residence and, if necessary, in coordination with the palliative care and/or home hospitalization teams (16, 17) .
    keywords: covid-19; hospital; nursing; patients
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        item: #5270 of 7819
          id: cord-322456-5at1euqm
      author: Rokohl, Alexander C.
       title: Die Rolle der Augenheilkunde in der COVID-19-Pandemie
        date: 2020-06-09
       words: 1849
      flesch: 40
     summary: Zudem soll die Rolle der Ophthalmologie bei der Therapie von COVID-19 erörtert werden. key: cord-322456-5at1euqm authors: Rokohl, Alexander C.; Loreck, Niklas; Wawer Matos, Philomena A.; Mor, Joel M.; Zwingelberg, Sarah; Grajewski, Rafael S.; Cursiefen, Claus; Heindl, Ludwig M. title: Die Rolle der Augenheilkunde in der COVID-19-Pandemie date: 2020-06-09 journal: Ophthalmologe DOI: 10.1007/s00347-020-01148-9 sha: doc_id:
    keywords: auch; bei; coronavirus; cov-2; covid-19; der; die; disease; eine; mit; patienten; sars; und; von
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        item: #5271 of 7819
          id: cord-322471-wt7zt6a8
      author: Raparelli, Valeria
       title: Sex differences in clinical phenotype and transitions of care among individuals dying of COVID-19 in Italy
        date: 2020-10-16
       words: 4048
      flesch: 40
     summary: Danish nationwide, register-based study Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy Region Analysis of 92 deceased patients with COVID-19 Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series Acute kidney injury in patients hospitalized with COVID-19 Survival rate in acute kidney injury superimposed COVID-19 patients: a systematic review and meta-analysis Acute kidney injury in COVID-19: emerging evidence of a distinct pathophysiology Fever and the thermal regulation of immunity: the immune system feels the heat Sex and gender differences in health Acute myocardial infarction in women: a scientific statement from the Age and sex in drug development and testing for adults Clinical trials for COVID-19 should include sex as a variable OpenSAFELY: factors associated with COVID-19 death in 17 million patients The influence of sex and gender domains on COVID-19 cases and mortality Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Authors' contributions V.R.: conception, design, acquisition of data, interpretation of data, drafting of the manuscript, and revision. Available at Sex differences in frailty: a systematic review and meta-analysis Frailty in older women The male-female health-survival paradox: a survey and register study of the impact of sex-specific selection and information bias Men: good health and high mortality Do sex differences in chronic disease underpin the sex-frailty paradox? COVID-19 and smoking: a systematic review of the evidence Age and multimorbidity predict death among COVID-19 patients: results of the SARS-RAS Study of the Italian Society of Hypertension Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Risk factors of critical & mortal COVID-19 cases: a systematic literature review and meta-analysis Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study Sex differences in immune responses Global, regional, and national burden of Alzheimer's disease and other dementias, 1990-2016: a systematic analysis for the Global Burden of Disease Study Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry Association between male sex and outcomes of coronavirus disease 2019 (Covid-19) -a
    keywords: admission; analysis; covid-19; data; disease; men; sex; women
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        item: #5272 of 7819
          id: cord-322474-izguwscl
      author: Rylett, R. J.
       title: Covid-19 and Priorities for Research in Aging
        date: 2020-09-02
       words: 2762
      flesch: 42
     summary: This article describes priority areas for research on the impact of the Covid-19 pandemic on older adults that have been identified by the CIHR Institute of Aging (CIHR-IA). The key research priority areas are as follows: response of older adults to disease, vaccination, and therapeutics; mental health and isolation; and supportive care environments.
    keywords: adults; care; cihr; covid-19; health; research
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        item: #5273 of 7819
          id: cord-322483-up3738e7
      author: Rocha, Hermano Alexandre Lima
       title: Dealing with the impact of the COVID-19 pandemic on a Rapid Response Team operation in Brazil: Quality in practice
        date: 2020-09-30
       words: 1672
      flesch: 50
     summary: The number of critically-ill cases and the number of treated patients increased two-fold in relation to the pre-pandemic period, but the effectiveness of the RRT in relation to mortality was not affected. The severity of illness of the treated patients also increased two-fold in relation to the previous period, leading to a scenario of a higher number of treated patients and more severely-ill individuals within the same day.
    keywords: cases; covid-19; pandemic; patients
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        item: #5274 of 7819
          id: cord-322486-qwl7nzkr
      author: Omori, Ryosuke
       title: The age distribution of mortality from novel coronavirus disease (COVID-19) suggests no large difference of susceptibility by age
        date: 2020-10-06
       words: 4859
      flesch: 39
     summary: The sensitivity of transmission coefficient β against age distribution of mortality when it was assumed that age-dependent mortality was proportional to cCFR per age group. We modelled age specific susceptibility as where c is susceptibility among age group 1 and a constant among all age groups, φ denotes the exponent parameter describing the variation of susceptibility among age groups.
    keywords: age; covid-19; distribution; infections; mortality; susceptibility
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        item: #5275 of 7819
          id: cord-322493-ymg6mh28
      author: Gheysarzadeh, Ali
       title: Report of 5 nurses infecting COVID-19 during patient care: case Series
        date: 2020-05-13
       words: 964
      flesch: 54
     summary: Findings In the present study 5 out of 125 nurses (4%) who enrolled in COVID-19 infection center, were infected with COVID-19. Infected nurses were in 33-39 years old (They were first positive for real-time PCR (TaKaRa, Japan) and their CT scan was performed after realtime PCR test (Fig. 1) .
    keywords: care; covid-19; nurses
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        item: #5276 of 7819
          id: cord-322497-hdy3va8e
      author: LUBANSU, Alphonse
       title: COVID-19 impact on neurosurgical practice: lockdown attitude and experience of a European academic center.
        date: 2020-09-03
       words: 1166
      flesch: 38
     summary: limited clinical neurosurgical experience including COVID-19 patients have been reported. The mortality rate of COVID-19 patients was remarkably high (45%), and even higher in patients that underwent surgical intervention (77 %).
    keywords: covid-19; infection; patients; test
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        item: #5277 of 7819
          id: cord-322525-22bt6zv8
      author: Gorges, Rebecca J.
       title: Staffing Levels and COVID‐19 Cases and Outbreaks in US Nursing Homes
        date: 2020-08-08
       words: 2568
      flesch: 53
     summary: We merged nursing home COVID-19 case and death counts with facility and county characteristics. Early analyses indicated that baseline quality was not predictive of nursing home cases, but a more nuanced study of the role of nurse staffing is needed to target resources and better respond to future outbreaks.
    keywords: cases; deaths; facilities; nursing; staffing
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        item: #5278 of 7819
          id: cord-322528-6r57pq8o
      author: Heald, Adrian H
       title: Modelling the impact of the mandatory use of face coverings on public transport and in retail outlets in the UK on COVID‐19‐related infections, hospital admissions and mortality
        date: 2020-10-18
       words: 2347
      flesch: 46
     summary: key: cord-322528-6r57pq8o authors: Heald, Adrian H; Stedman, Michael; Tian, Zixing; Wu, Pensee; Fryer, Anthony A title: Modelling the impact of the mandatory use of face coverings on public transport and in retail outlets in the UK on COVID‐19‐related infections, hospital admissions and mortality date: 2020-10-18 journal: Int J Clin Pract DOI: 10.1111/ijcp.13768 sha: doc_id: 322528 cord_uid: 6r57pq8o INTRODUCTION: The rapid spread of the pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2/)(COVID‐19) virus resulted in governments around the world instigating a range of measures, including mandating the wearing of face coverings on public transport/in retail outlets.
    keywords: coverings; face; infections; public; transport; use
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        item: #5279 of 7819
          id: cord-322543-lo1ra50f
      author: Li, z.
       title: Causal Analysis of Health Interventions and Environments for Influencing the Spread of COVID-19 in the United States of America
        date: 2020-09-29
       words: 4443
      flesch: 50
     summary: https://doi.org/10.1101/2020.09.29.20203505 doi: medRxiv preprint COVID-19 in 46 states and significant cause of death in 47 states. Environmental perspective of COVID-19 Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe School closure and management practices during coronavirus outbreaks including COVID-19: a rapid systematic review Digital technologies in the public-health response to COVID-19 Effectiveness of airport screening at detecting travelers infected with 2019-nCoV Applications of digital technology in COVID-19 pandemic planning and response Association, correlation and causation The Causal Effect of Social Distancing on the Spread of SARS-CoV-2 Causal analysis of COVID-19 observational data in German districts reveals effects of mobility, awareness, and temperature Difference-in-Differences to Identify Causal Effects of COVID-19 Policies.
    keywords: cases; copyright; copyright holder; covid-19; domain; peer; preprint; review
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        item: #5280 of 7819
          id: cord-322552-95bj65qf
      author: Sang, Charlie Joseph
       title: ST Elevations in the Era of COVID-19
        date: 2020-08-06
       words: 2657
      flesch: 37
     summary: This scenario also raises important questions in the management of COVID-19 patients with ST elevation myocardial infarction in the United States, where percutaneous coronary intervention (PCI) is the standard of care. The use of ticagrelor in the setting of COVID-19 myocardial infarction requires further attention.
    keywords: acute; coronary; covid-19; disease; myocardial; myopericarditis; patients
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        item: #5281 of 7819
          id: cord-322571-8u4c2xqg
      author: Sannigrahi, Srikanta
       title: Examining the association between socio-demographic composition and COVID-19 fatalities in the European region using spatial regression approach
        date: 2020-08-01
       words: 6153
      flesch: 35
     summary: Spatial regressions models have been used extensively in many epidemiological studies ranges across the scale . The specific application of spatial regression models is to understand the spatial effects such as spatial autocorrelation, spatial stationarity, and heterogeneity of feature distribution.
    keywords: association; cases; covid-19; deaths; fig; model; regression; socio; spatial; variables
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        item: #5282 of 7819
          id: cord-322572-wic7n6ia
      author: Liu, Jiangtao
       title: Impact of meteorological factors on the COVID-19 transmission: A multi-city study in China
        date: 2020-07-15
       words: 3970
      flesch: 47
     summary: First, we explored the associations between COVID-19 confirmed case counts, meteorological factors, and MSI using non-linear regression. First, we explored the associations between COVID-19 confirmed case counts, meteorological factors, and MSI using non-linear regression.
    keywords: case; cities; counts; covid-19; temperature
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        item: #5283 of 7819
          id: cord-322577-5bboc1z0
      author: Parola, Anna
       title: Mental Health Through the COVID-19 Quarantine: A Growth Curve Analysis on Italian Young Adults
        date: 2020-10-02
       words: 6610
      flesch: 38
     summary: If, broadly, the results obtained confirmed the general detrimental effects of social isolation due to epidemics on young adults' mental health (Hawryluck et al., 2004; Tucci et al., 2017; Qiu et al., 2020; Wang et al., 2020) , some brief reflections need to be outlined about the specificities of young adults' condition. On the basis of recent literature on the general population, an increase in mental health problems among young adults during quarantine was hypothesized.
    keywords: adults; covid-19; et al; health; lockdown; model; participants; problems; psychological; scales; study
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        item: #5284 of 7819
          id: cord-322580-7ohso8hl
      author: Stochino, Claudia
       title: Clinical characteristics of COVID-19 and active tuberculosis co-infection in an Italian reference hospital
        date: 2020-06-01
       words: 1321
      flesch: 46
     summary: This study describes clinical, radiological, and laboratory characteristics of a series of COVID-19 patients with concurrent active TB in a hospital in Sondrio province, Region Lombardy in northern Italy. key: cord-322580-7ohso8hl authors: Stochino, Claudia; Villa, Simone; Zucchi, Patrizia; Parravicini, Pierpaolo; Gori, Andrea; Raviglione, Mario Carlo title: Clinical characteristics of COVID-19 and active tuberculosis co-infection in an Italian reference hospital date: 2020-06-01 journal: Eur Respir J DOI: 10.1183/13993003.01708-2020 sha: doc_id: 322580 cord_uid: 7ohso8hl The COVID-19 infection rate was high in patient with active tuberculosis.
    keywords: covid-19; days; diagnosis; patients
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        item: #5285 of 7819
          id: cord-322590-twnlaq24
      author: Hoyer, Carolin
       title: Changes in Demographic and Diagnostic Spectra of Patients with Neurological Symptoms Presenting to an Emergency Department During the COVID-19 Pandemic: A Retrospective Cohort Study
        date: 2020-09-30
       words: 3057
      flesch: 34
     summary: The year 2017 was chosen because data from ED patients of that year were fully and readily available, allowing for a rapid and timely comparative analysis with the COVID-19 epoch in 2020. In calendar week 1-15 of 2017, a total of 1511 patients presented with neurological symptoms to the ED, while in calendar weeks 1-15 of 2020, there were 1403 neurological ED patients.
    keywords: care; covid-19; department; emergency; pandemic; patients; weeks
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        item: #5286 of 7819
          id: cord-322596-vfmzk2el
      author: Ming, Yi
       title: Involvement of Spike Protein, Furin, and ACE2 in SARS-CoV-2-Related Cardiovascular Complications
        date: 2020-07-11
       words: 3612
      flesch: 36
     summary: The biological process of Furin processing and activation of coronavirus S protein to expose the reactive domain also explains partially the phenomenon of COVID-19 with severe cardiovascular damage. Moreover, based on the role of furin protein in cardiovascular disease, its inhibitors might also improve cardiovascular prognosis and reduce critical deaths.
    keywords: ace2; cell; cov-2; covid-19; furin; patients; protein; sars
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        item: #5287 of 7819
          id: cord-322601-9pg1yqfa
      author: Camporota, Luigi
       title: Outcomes in mechanically ventilated patients with hypoxaemic respiratory failure due to COVID-19
        date: 2020-09-03
       words: 909
      flesch: 39
     summary: These results illustrate that although the characteristics of the COVID-19 AHRF population largely overlap with the LUNG-SAFE cohort, the COVID-19 cohort had a greater predominance of moderate (57% vs 47%) and severe (31% vs 23%) and a lower proportion of patients with mild hypoxaemia (10.8% vs 30%) compared to the LUNG-SAFE cohort 7 . Concept and design: LC, BS, MS-H Statistical analysis: BS, CaLCmporota Drafting of manuscript: LC, MS-H Acquisition, analysis and interpretation of data: All authors Critical revision of the manuscript for important intellectual content: All authors Obtained funding: LC Administrative, technical, or material support: LC, AJ Supervision: LC, MS-H Funding MS-H is supported by the National Institute for Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Acute respiratory distress syndrome: the Berlin Definition COVID-19 Does Not Lead to a Typical Acute Respiratory Distress Syndrome Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19 High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Immune mechanisms of pulmonary intravascular coagulopathy in COVID-19 pneumonia Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries ICU and Ventilator Mortality Among Critically Ill Adults With Coronavirus Disease
    keywords: cohort; covid-19; patients
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        item: #5288 of 7819
          id: cord-322641-mz0b91xr
      author: Farnsworth, Christopher W
       title: SARS-CoV-2 Serology: Much Hype, Little Data
        date: 2020-04-28
       words: 1568
      flesch: 40
     summary: In response to a lack of COVID-19 testing the FDA issued guidance regarding serologic assays, stating that although manufacturers could use the Emergency Use Authorization (EUA) pathway for approval, serologic assays could also be marketed in the US bypassing this approval process (2) . Serologic assays are unlikely to be useful for this application.
    keywords: assays; cov-2; serologic; specificity
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        item: #5289 of 7819
          id: cord-322645-ipzntrm2
      author: Dutta, Anwesha
       title: The local governance of COVID-19: Disease prevention and social security in rural India
        date: 2020-10-17
       words: 7548
      flesch: 33
     summary: Through a combination of interviews with mid and low-level bureaucrats and a review of policy documents, we show how the urgency of COVID-19 response has galvanized new kinds of cross-sectoral and multi-scalar interaction between administrative units involved in coordinating responses, as local governments have assumed central responsibility in the implementation of disease control and social security mechanisms. As a country with over 250,000 local governmental units (gram panchayats), India has undertaken what is arguably the largest and most expansive mobilization of local governments around the world to the current crisis.
    keywords: control; covid-19; district; governance; government; health; india; institutions; level; panchayats; pandemic; public; response; state
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        item: #5290 of 7819
          id: cord-322660-bis2arbu
      author: Alexander, Regi
       title: Guidance for the Treatment and Management of COVID‐19 Among People with Intellectual Disabilities
        date: 2020-06-10
       words: 10811
      flesch: 39
     summary: Changes to medication may be required to assist in the management of mental health symptoms, and some individuals may require depot medication which is administered by general practitioners, community nurses within community learning disabilities or mental health teams. The role of community learning disabilities teams is to provide input into healthcare about specific vulnerabilities, highlighting disparity, and helping to reduce the risk of infection.
    keywords: care; carers; community; covid-19; disabilities; england; health; hospital; ids; learning; people; risk; support; teams; treatment
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        item: #5291 of 7819
          id: cord-322663-a58e6pp8
      author: Giacomelli, Andrea
       title: 30-day mortality in patients hospitalized with COVID-19 during the first wave of the Italian epidemic: a prospective cohort study
        date: 2020-05-22
       words: 3165
      flesch: 43
     summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges WHO Director-General's opening remarks at the media briefing on COVID-19 -11 Clinical features of patients infected with 2019 novel coronavirus in Wuhan A Novel Coronavirus from Patients with Pneumonia in China Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: COVID-19: the gendered impacts of the outbreak Kidney disease is associated with in-hospital death of patients with COVID-19 Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area Clinical Characteristics of Coronavirus Disease 2019 in China Analysis of Epidemiological and Clinical features in older patients with Corona Virus Disease
    keywords: admission; covid-19; death; disease; epidemic; patients; study
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        item: #5292 of 7819
          id: cord-322672-gjph61cq
      author: Ashok, Vishnu
       title: Case report: high-grade atrioventricular block in suspected COVID-19 myocarditis
        date: 2020-08-25
       words: 1819
      flesch: 45
     summary: key: cord-322672-gjph61cq authors: Ashok, Vishnu; Loke, Wei Ian title: Case report: high-grade atrioventricular block in suspected COVID-19 myocarditis date: 2020-08-25 journal: Eur Heart J Case Rep DOI: 10.1093/ehjcr/ytaa248 sha: doc_id: 322672 cord_uid: gjph61cq BACKGROUND: In the ongoing pandemic of COVID-19, respiratory failure has been reported as the main cause of death in those who develop critical illness. CASE SUMMARY: A 53-year-old man, suspected to have COVID-19 due to a new-onset cough, shortness of breath, and hypoxia, was referred to Cardiology with sudden symptomatic bradycardia.
    keywords: block; cardiac; covid-19; myocarditis; patients
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        item: #5293 of 7819
          id: cord-322693-q3h15hd6
      author: Crowley, Des
       title: Prison and opportunities for the management of COVID-19
        date: 2020-06-10
       words: 1377
      flesch: 46
     summary: 12 There have been numerous calls for increased involvement of public health specialists in prison health care, and it is recognised that improving the health of prisons will ultimately improve the health of the wider community. This is a once in a generation opportunity to embed prison health into public health, and it should not be missed The current pandemic provides an unprecedented opportunity to review the purpose of incarceration, historically seen as punishment and rehabilitation.
    keywords: covid-19; health; prison; prisoners
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        item: #5294 of 7819
          id: cord-322704-0suc6pt6
      author: Riffe, T.
       title: COVeAGE-DB: A database of age-structured COVID-19 cases and deaths.
        date: 2020-09-23
       words: 2904
      flesch: 49
     summary: These studies aim t o: (i) explore country differences in the age distribution of COVID-19 deaths, 2 (ii) assess the contributi on of infection case age-structure and age-specific fatality to between-and within-country differences in case fatality rates (CFR) associated with the COVID-19, 3 (iii) produce a standard age-specific case fatality rate pattern for an indirect demographic method to estimate COVID-19 total infections, 4 (iv) analyze the association between intergenerational relationships and COVID-19 fatality rates, 5 (v) estimate years of life lost due to Covid-19, 6 and (vi) calculate pooled sex ratios of age-specific CFRs of COVID-19 in Europe. While most populations currently report all deaths to confirmed COVID-19 infections as COVID-19 deaths for this database, the underlying cause of death eventually reported on death certificates may differ in patients with severe comorbidities.
    keywords: age; coverage; covid-19; data; database; deaths; medrxiv; preprint
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        item: #5295 of 7819
          id: cord-322711-u6yr8wqh
      author: Imran, Nazish
       title: Psychological burden of quarantine in children and adolescents: A rapid systematic review and proposed solutions
        date: 2020
       words: 4936
      flesch: 40
     summary: The Lancet Commission on the future of the world's children urges various stakeholders to ensure that all children's needs are met during these uncertain times as early investment in children health, education and development have benefits that compound throughout the child's lifetime, and societies as a whole. While younger children may be clingier or regress in behaviors, older children may become more anxious, angry, restless and withdrawn while in Quarantine.
    keywords: adolescents; children; covid-19; health; impact; parents; quarantine; review; stigma; studies
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        item: #5296 of 7819
          id: cord-322714-s0wge7o4
      author: Joyner, Michael J.
       title: Safety Update: COVID-19 Convalescent Plasma in 20,000 Hospitalized Patients
        date: 2020-07-19
       words: 3295
      flesch: 40
     summary: Although thrombotic and thromboembolic events are emerging clinical complications of COVID-19 11, 12, 20 , our data demonstrate a low rate (<1%) of these events within the first seven days after COVID-19 convalescent plasma transfusion. Patients and Methods From April 3 to June 2, 2020, the US FDA Expanded Access Program for COVID-19 convalescent plasma transfused a convenience sample of 20,000 hospitalized patients with COVID-19 convalescent plasma.
    keywords: convalescent; covid-19; data; events; mortality; patients; plasma; transfusion
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        item: #5297 of 7819
          id: cord-322718-zpf2ri9k
      author: Goldust, Mohamad
       title: Dermatology and specialty rotations: COVID‐19 may reemphasize the importance of internal medicine
        date: 2020-07-11
       words: 509
      flesch: 30
     summary: In brief, internal medicine rotations should be made mandatory for dermatologists as this foundation may of use not only for our professional routine but also for exceptional healthcare crisis such as COVID-19. [1] [2] [3] In dire times like this, other specialists including dermatologists have stepped up and volunteered their services to help ease the burden and share the medical workload.
    keywords: covid-19; dermatology
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        item: #5298 of 7819
          id: cord-322723-qmnorud2
      author: Goetz, Christian
       title: Lung Scintigraphy Imaging Features in a Young Patient With COVID-19
        date: 2020-06-25
       words: 564
      flesch: 33
     summary: Sensitivity of chest CT for COVID-19: comparison to RT-PCR Essentials for radiologists on COVID-19: an update radiology scientific expert panel COVID-19 pneumonia: what has CT taught us Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia 18 F-FDG PET/CT findings of COVID-19: a series of four highly suspected cases 18 F-FDG PET/CT and serial chest CT findings in a COVID-19 patient with dynamic clinical characteristics in different period Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2 Coronavirus SARS-CoV-2: Empfehlungen für die nuklearmedizinische Versorgung in nuklearmedizinischen Kliniken/Abteilungen mit Therapiestation und Praxen Diagnostic evaluation of pulmonary embolism during the COVID-19 pandemic key: cord-322723-qmnorud2 authors: Goetz, Christian; Fassbender, Thomas F.; Meyer, Philipp T. title: Lung Scintigraphy Imaging Features in a Young Patient With COVID-19 date: 2020-06-25 journal: Clin Nucl Med DOI: 10.1097/rlu.0000000000003196 sha: doc_id: 322723 cord_uid: qmnorud2
    keywords: coronavirus; covid-19
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        item: #5299 of 7819
          id: cord-322725-fjd7cbvb
      author: Ghaffarpasand, Fariborz
       title: Early Tracheostomy in Trauma Patients with Acute Respiratory Distress Syndrome due to Novel Coronavirus Disease 2019 (COVID-19)
        date: 2020-07-17
       words: 820
      flesch: 44
     summary: In addition, early tracheostomy decreases the rate of respiratory infections and used antibiotics in trauma patients [12, 13] . In conclusion, based on the published evidence and our previous experience in trauma patients, we postulate that early tracheostomy could be associated with improved outcome in patients with COVID-19 and ADRS experiencing traumatic injuries.
    keywords: patients; tracheostomy
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        item: #5300 of 7819
          id: cord-322732-82m84n4w
      author: Felice, C
       title: Use of RAAS inhibitors and risk of clinical deterioration in COVID-19: results from an Italian cohort of 133 hypertensives
        date: 2020-06-08
       words: 1775
      flesch: 42
     summary: Our data suggest that chronic use of RAAS inhibitors does not negatively affect clinical course of COVID-19 in hypertensive patients. No significant differences were observed for all demographics and clinical parameters, except for the history of chronic heart failure, which was more frequently observed in hypertensive patients not on RAAS inhibitors (31%; P=0.007).
    keywords: arbs; covid-19; inhibitors; patients
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        item: #5301 of 7819
          id: cord-322733-rriuiofu
      author: Li, Weiran
       title: Changes in sexual behaviors of young women and men during the coronavirus disease 2019 outbreak: a convenience sample from the epidemic area
        date: 2020-04-29
       words: 813
      flesch: 45
     summary: key: cord-322733-rriuiofu authors: Li, Weiran; Li, Guanjian; Xin, Cong; Wang, Yaochi; Yang, Sen title: Changes in sexual behaviors of young women and men during the coronavirus disease 2019 Currently, data on changes in sexual behavior during the COVID-19 outbreak are limited.
    keywords: behavior; covid-19; outbreak
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        item: #5302 of 7819
          id: cord-322776-jg8hqlu7
      author: Raharja, Antony
       title: Association Between Ethnicity and Severe COVID-19 Disease: a Systematic Review and Meta-analysis
        date: 2020-11-12
       words: 4449
      flesch: 41
     summary: ↑*Significant risk factor; ↑Potential risk factor; non-significant risk ratio > 1.5; risk ratio between 0.67 and 1.5; ↓Potentially protective; non-significant risk ratio < 0.67; ↓*Significant protective COVID-19 risk assessment should only consider ethnicity in conjunction with other risk factors such as age or comorbidities. medRxiv Are black and Hispanic persons disproportionately affected by COVID-19 because of higher obesity rates? Risk factors associated with mortality of COVID-19 in 2692 counties of the United States.
    keywords: analysis; covid-19; ethnicity; hispanic; meta; outcomes; patients; risk; studies
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        item: #5303 of 7819
          id: cord-322787-dbtc0bo3
      author: Runkle, Jennifer D.
       title: Short-term effects of weather parameters on COVID-19 morbidity in select US cities
        date: 2020-06-09
       words: 3494
      flesch: 39
     summary: However, the relationship with temperature and humidity is not yet apparent for COVID-19 cases in US cities first impacted. The objective of this study is to evaluate the association between COVID-19 cases and weather parameters in select US cities.
    keywords: cases; covid-19; humidity; temperature
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        item: #5304 of 7819
          id: cord-322789-9elfpx0e
      author: Abbaspour Kasgari, Hamideh
       title: Evaluation of the efficacy of sofosbuvir plus daclatasvir in combination with ribavirin for hospitalized COVID-19 patients with moderate disease compared with standard care: a single-centre, randomized controlled trial
        date: 2020-08-19
       words: 2713
      flesch: 43
     summary: To our knowledge, this is the first clinical trial of sofosbuvir/ daclatasvir/ribavirin in COVID-19 patients; however, there are limitations to our study. Time to recovery was compared by graphically plotting the cause-specific cumulative incidence functions (CIFs) by treatment group; difference between groups was evaluated by Gray's test for the equality of CIFs.
    keywords: covid-19; daclatasvir; group; patients; ribavirin; sofosbuvir; study
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        item: #5305 of 7819
          id: cord-322796-ojfrvtuy
      author: Bagheri, S. H. R.
       title: Coincidence of COVID-19 epidemic and olfactory dysfunction outbreak
        date: 2020-03-27
       words: 2242
      flesch: 43
     summary: Correlation between the number of olfactory disorder and reported COVID-19 patients in all 31 provinces till 16th March 2020 was highly significant (Spearman correlation coefficient=0.87, p-Value<0.001). The exact mechanism of anosmia/hyposmia in COVID-19 patients needs further investigations. .
    keywords: anosmia; covid-19; license; medrxiv; preprint
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        item: #5306 of 7819
          id: cord-322798-5r3kf9wa
      author: Freeman, Esther E.
       title: Creating Dermatology Guidelines for Covid-19: The Pitfalls of Applying Evidence Based Medicine to an Emerging Infectious Disease
        date: 2020-04-09
       words: 675
      flesch: 45
     summary: Issues include how to grade evidence from gray literature, risks and benefits of use of anecdotal experiences and indirect evidence, and harmonizing guidance simultaneously produced by other organizations. While we commend the authors for compiling this data, there are several issues with indirect evidence: i) these trials compared biologics to placebo, ii) they were not powered for the outcome of URI, and iii) the similarity of Covid-19 to URI is unknown.
    keywords: covid-19; evidence
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        item: #5307 of 7819
          id: cord-322799-opf1qwgl
      author: Hiremath, Channabasavaraj Shivalingaiah
       title: IACTS guidelines: practice of cardiovascular and thoracic surgery in the COVID-19 era
        date: 2020-08-11
       words: 3944
      flesch: 47
     summary: There is a proven increased risk in morbidity and mortality in COVID-19 patients undergoing cardiac surgery [13] . Deferring care to such patients can aggravate risk and potentially turn fatal.
    keywords: cardiac; care; cases; covid-19; guidelines; health; patient; risk; surgery; swab; use
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        item: #5308 of 7819
          id: cord-322812-9u3ptqjs
      author: Wells, Philippa M.
       title: Estimates of the rate of infection and asymptomatic COVID-19 disease in a population sample from SE England
        date: 2020-10-15
       words: 3734
      flesch: 45
     summary: Symptom profiling included core COVID-19 symptoms and general symptoms, in addition to algorithm prediction of prior COVID-19. Of 48 seropositive individuals with full symptom data, nine (19%) were fully asymptomatic, and 16 (27%) were asymptomatic for core COVID-19 symptoms: fever, cough or anosmia.
    keywords: anosmia; antibody; app; asymptomatic; covid-19; infection; participants; sars; study; symptoms
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        item: #5309 of 7819
          id: cord-322838-s82tyeis
      author: Norden, M. J.
       title: National Smoking Rates Correlate Inversely with COVID-19 Mortality
        date: 2020-06-14
       words: 5299
      flesch: 44
     summary: In hot countries, for each percentage point increase in smoking rate mortality decreased by .147 per 100,000 population (95% CI .102- 192, p=.0066). Mortality rates were determined as of May 1, 2020 and correlated with national smoking rate adjusting for sex ratio, obesity, temperature, and elderly population.
    keywords: countries; covid-19; mortality; patients; preprint; prevalence; rates; smokers; smoking; study
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        item: #5310 of 7819
          id: cord-322861-q7uk6rdp
      author: Zanon, Ezio
       title: How haemophilia A impacts severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) treatment: a case report
        date: 2020-07-16
       words: 2118
      flesch: 40
     summary: Even if much more data are needed to ascertain the real thrombotic risk of haemophilia A in COVID-19 patients, it’s clear that the FVIII and vWF should be strictly monitored in order to promptly establish an adequate treatment and avoid the onset of thromboembolic events, even fatal, causing many deaths in COVID-19 patients. In addition to respiratory complications, several changes in the coagulation processes have been observed in COVID-19 patients such as elevated D-dimer, reduced platelet count, disseminated intravascular coagulation (DIC), thrombotic microangiopathies (2, 3) .
    keywords: coagulation; covid-19; haemophilia; levels; n.v; patient
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        item: #5311 of 7819
          id: cord-322866-au76nnzg
      author: Bleizgys, Andrius
       title: Vitamin D and COVID‐19: It is time to act
        date: 2020-10-27
       words: 6039
      flesch: 39
     summary: https://orcid.org/0000-0002-0285-6123 A comprehensive literature review on the clinical presentation, and management of the pandemic coronavirus disease 2019 (COVID-19) Rheumatologists' perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets COVID-19: the inflammation link and the role of nutrition in potential mitigation Evidence that vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths Mechanism of inflammatory response in associated comorbidities in COVID-19 The physiology of vitamin D-far more than calcium and bone Vitamin D: extraskeletal health Vitamin D review Worldwide vitamin D status Vitamin D status and nutrition in Europe and Asia Vitamin d status in central europe A global representation of vitamin D status in healthy populations Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency: a position statement of the European Calcified Tissue Society Scientific Strabismus' or two related pandemics: coronavirus disease and vitamin D deficiency Vitamin D: drug of the future. Med Hypotheses Role of vitamin D in preventing of COVID-19 infection, progression and severity Vitamin D insufficiency as a potential culprit in critical COVID-19 patients Optimisation of vitamin D status for enhanced immuno-protection against covid-19 Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey Perspective: improving vitamin D status in the management of COVID-19 Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment Vitamin D deficiency and air pollution exacerbate COVID-19 through suppression of antiviral peptide LL37.
    keywords: 25oh; covid-19; deficiency; levels; patients; risk; supplementation; vitamin; vitamin d; vitd
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        item: #5312 of 7819
          id: cord-322867-1yxxe5d3
      author: Hartman, William R
       title: Hospitalized COVID-19 Patients treated with Convalescent Plasma in a Mid-size City in the Midwest
        date: 2020-07-14
       words: 2902
      flesch: 44
     summary: (8-10) We describe our experience treating a series of COVID-19 patients with severe or life-threatening disease with convalescent plasma. Our results are consistent with other early reports of outcomes in COVID-19 patients transfused with convalescent plasma.
    keywords: convalescent; covid-19; disease; life; patients; plasma
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        item: #5313 of 7819
          id: cord-322868-o3r0y6bz
      author: Williams, E. J.
       title: Routine measurement of serum procalcitonin allows antibiotics to be safely withheld in patients admitted to hospital with SARS-CoV-2 infection.
        date: 2020-07-02
       words: 2833
      flesch: 37
     summary: STHNFT guidelines recommended that antibiotics could be withheld in COVID-19 patients with a PCT value of ≤ 0.25ng/ml unless felt necessary by a senior clinician, as concomitant bacterial infection is unlikely in such patients [19] . It is possible that some patients may have been readmitted to other regional hospitals, but this is felt unlikely as the Treatment of Community-Acquired Pneumonia During the Coronavirus Disease 2019 (COVID-19) Pandemic Prognostic value of interleukin-6, C-reactive protein, and procalcitonin in patients with COVID-19 Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Procalcitonin in patients with severe coronavirus disease 2019 (COVID-19): A meta-analysis Impact of Procalcitonin-Guided Antibiotic Management on Antibiotic Exposure and Outcomes: Real-world Evidence Improved sensitivity using a dual target, E and RdRp assay for the diagnosis of SARS-CoV-2 infection: Experience at a large NHS Foundation Trust in the UK Effectiveness of a procalcitonin algorithm to guide antibiotic therapy in respiratory tract infections outside of study conditions: a post-study survey Metrics for quantifying antibiotic use in the hospital setting: results from a systematic review and international multidisciplinary consensus procedure Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: clusterrandomised, single-blinded intervention trial Efficacy and safety of procalcitonin guidance in reducing the duration of antibiotic treatment in critically ill patients: a randomised, controlled, open-label trial Assessment of Procalcitonin as a Diagnostic Marker of Underlying Infection in Patients with Febrile Neutropenia Markers of bacteremia in febrile neutropenic patients with hematological malignancies: procalcitonin and IL-6 are more reliable than C-reactive protein Procalcitonin and Proinflammatory Cytokine Clearance during Continuous Venovenous Haemofiltration in Septic Patients
    keywords: antibiotics; covid-19; infection; negative; patients; pct; procalcitonin
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        item: #5314 of 7819
          id: cord-322899-uxvlagt3
      author: Gorji, Ali
       title: The potential roles of micronutrient deficiency and immune system dysfunction in COVID-19 pandemic
        date: 2020-11-06
       words: 4931
      flesch: 24
     summary: [62] Clinical investigations and in vitro studies have indicated that vitamin A is the main regulator of mucosal immunity and could affect immune responses to mucosal infections. ISRN Infectious Diseases ID 246737 Effects of vitamin a supplementation on immune responses and correlation with clinical outcomes Vitamin-mediated regulation of intestinal immunity High-dose dietary zinc oxide mitigates infection with transmissible gastroenteritis virus in piglets Effects of dietary vitamin A content on antibody responses of feedlot calves inoculated intramuscularly with an inactivated bovine coronavirus vaccine Epithelia-damaging virus infections affect vitamin A status in chickens Metabolism of Dietary and Microbial Vitamin B Family in the Regulation of Host Immunity The effects of vitamin B on the immune/cytokine network and their involvement in depression Vitamin B5 reduces bacterial growth via regulating innate immunity and adaptive immunity in mice infected with Mycobacterium tuberculosis Effects of vitamin B6 deficiency on the composition and functional potential of T cell populations Inflammation, vitamin B6 and related pathways
    keywords: cells; covid-19; deficiency; host; immune; infection; micronutrients; patients; response; system; virus; vitamin; zinc
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        item: #5315 of 7819
          id: cord-322908-e3gok0ot
      author: Huang, Fangfang
       title: A review of therapeutic agents and Chinese herbal medicines against SARS-COV-2 (COVID-19)
        date: 2020-05-20
       words: 5067
      flesch: 28
     summary: Analysis on the application of Traditional Chinese Medicine in the treatment of COVID-19 by suppressing cytokine storm One-Compound-Multi-Target: Combination Prospect of Natural Compounds with Thrombolytic Therapy in Acute Ischemic Stroke Baicalin ameliorates oxidative apoptosis by restoring mitochondrial dynamics in the spleen of chickens via the opposite modulation of NF-kappaB and Nrf2/HO-1 signaling pathway during Mycoplasma gallisepticum infection In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds Inhibitory activities of baicalin against renin and angiotensin-converting enzyme Availability, Pharmaceutics, Security, Pharmacokinetics, and Pharmacological Activities of Patchouli Alcohol, Evid Based Complement Alternat Med Antiviral potential of ERK/MAPK and PI3K/AKT/mTOR signaling modulation for Middle East respiratory syndrome coronavirus infection as identified by temporal kinome analysis Inhibition effects of patchouli alcohol against influenza a virus through targeting cellular PI3K/Akt and ERK/MAPK signaling pathways Oral administration of patchouli alcohol isolated from Pogostemonis Herba augments protection against influenza viral infection in mice Novel extraction techniques and pharmaceutical activities of luteolin and its derivatives Therefore, it can be reasonably speculated that baicalin is one of the potential drugs for COVID-19 treatment.
    keywords: activity; anti; clinical; coronavirus; cov-2; covid-19; effect; novel; patients; pneumonia; potential; sars; treatment; trial
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        item: #5316 of 7819
          id: cord-322913-sq9mq6f1
      author: Ciabattini, Annalisa
       title: Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly population
        date: 2020-11-06
       words: 8078
      flesch: 24
     summary: The immunogenicity of 7-valent pneumococcal conjugate vaccine versus 23-valent polysaccharide vaccine in adults aged 50-80 years Study of the effectiveness of influenza vaccination in the elderly in the epidemic of 1989-90 using a general practice database Effectiveness of influenza vaccine in the community-dwelling elderly Effect of influenza vaccine status on winter mortality in Spanish community-dwelling elderly people during 2002-2005 influenza periods Efficacy and costeffectiveness of influenza vaccination of the elderly in a densely populated and unvaccinated community Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination A single dose of unadjuvanted novel 2009 H1N1 vaccine is immunogenic and well tolerated in young and elderly adults Immune response following H1N1pdm09 vaccination: differences in antibody repertoire and avidity in young adults and elderly populations stratified by age and gender Role of the microbiota in the modulation of vaccine immune responses The influence of the intestinal microbiome on vaccine responses Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans Recent advances in systems biology integrating clinical, immunologic, and omics data can help to identify stable and robust markers of vaccine response and move towards a better understanding of SARS-CoV-2 vaccine responses in the elderly.
    keywords: age; aging; cells; cov-2; covid-19; development; disease; gut; infection; influenza; microbiota; patients; population; responses; sars; vaccination; vaccine
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        item: #5317 of 7819
          id: cord-322919-5ty35rsy
      author: Busana, Mattia
       title: Non‐invasive hemodynamic profile of early COVID‐19 infection
        date: 2020-10-28
       words: 2511
      flesch: 44
     summary: Thus, we would have expected to find signs of increased pulmonary pressure, but this was not the case. Furthermore, Sonzogni et al. (2020) described severe alterations in hepatic blood flow with massive portal vessel dilations in autopsies from COVID-19 patients.
    keywords: covid-19; patients; svri
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        item: #5318 of 7819
          id: cord-322957-clf8f90t
      author: Crespo, Javier
       title: Resumption of activity in gastroenterology departments. Recommendations by SEPD, AEEH, GETECCU and AEG
        date: 2020-04-28
       words: 5301
      flesch: 46
     summary: General recommendations regarding the treatment of patients with IBD, which must remain in force during the gradual resumption of activities: a. Patients must not discontinue medication or visits to the infusion center, or start self-medication, without consulting with their doctor first. A possible reason explaining this lower number of cases of COVID-19 in IBD patients may be this population's adherence to protective measures.
    keywords: activity; care; cov-2; covid-19; disease; ibd; infection; pandemic; patients; phase; recommendations; risk; sars
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        item: #5319 of 7819
          id: cord-322966-o65fo853
      author: Arnold, Ruth H.
       title: COVID-19 – Does This Disease Kill Due to Imbalance of the Renin Angiotensin System (RAS) Caused by Genetic and Gender Differences in the Response to Viral ACE 2 Attacks?
        date: 2020-05-25
       words: 5418
      flesch: 40
     summary: RAS medications can be used with greater confidence in COVID-19 patients with valid indications for their use, but a broader role for manipulation of the RAS in COVID-19 will require randomised trial data. Three (3) large observational studies reported in the NEJM have now examined this issue and found no evidence for increased risk of adverse outcomes in COVID-19 patients taking ACEI or ARBs [10, 13, 14] adding weight to previously reported smaller retrospective clinical studies [28] [29]
    keywords: ace; angiotensin; coronavirus; covid-19; differences; disease; patients; ras; role; system
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        item: #5320 of 7819
          id: cord-322980-rembksdr
      author: Talwar, Shivangi
       title: Ayurveda and Allopathic Therapeutic Strategies in Coronavirus Pandemic Treatment 2020
        date: 2020-10-22
       words: 4546
      flesch: 42
     summary: Therefore, Arsenicum album may be considered as a suitable remedy for COVID-19 treatment. This short review summarizes the role of allopathic and Ayurveda in coronavirus infections.
    keywords: ayurveda; coronavirus; covid-19; disease; homeopathy; infection; novel; pandemic; patients; review; sars; syndrome; treatment
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        item: #5321 of 7819
          id: cord-322996-ormqm6dx
      author: Wells, Rebecca Erwin
       title: The Value of Headache‐Specific Recommendations During COVID‐19
        date: 2020-04-26
       words: 2171
      flesch: 36
     summary: Providers can utilize this publication to help make effective decisions about treatment approaches for headache patients in the midst of the current COVID pandemic. While many medical centers have already recommended all headache procedures pause, some centers are asking providers to give guidance on whether clinic visits or procedures for headache patients are essential.
    keywords: care; covid; headache; patients; treatment
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        item: #5322 of 7819
          id: cord-323020-9v44cg3b
      author: Khaliq, Maria
       title: An Analysis of High-Resolution Computed Tomography Chest Manifestations of COVID-19 Patients in Pakistan
        date: 2020-07-24
       words: 2651
      flesch: 56
     summary: Methods In this cross-sectional descriptive study conducted from March 30, 2020, to May 30, 2020, 87 confirmed COVID-19 patients undergoing HRCT scan in a tertiary care facility in Punjab, Pakistan were included. This explains the lesser involvement of other organ functions in COVID-19 patients.
    keywords: covid-19; disease; patients; study
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        item: #5323 of 7819
          id: cord-323054-m8hkj1dm
      author: Schwartz, Rachel
       title: Addressing Postpandemic Clinician Mental Health: A Narrative Review and Conceptual Framework
        date: 2020-08-21
       words: 4846
      flesch: 30
     summary: Tools for routine assessment of mental health status, such as Zung's self-rating depression scale and self-rating anxiety scale for self-monitoring (55-57); training health care workers to identify physical, behav-ioral, emotional, and cognitive indices of distress in themselves and colleagues; and regular visits from mental health clinicians to assess the well-being of frontline providers are needed (18, 31, 58) . This support should target resilience and stress reduction training, ensure that clinicians' basic needs are met, provide routine opportunities for social connection, and proactively normalize and deliver mental health care to clinicians.
    keywords: care; clinicians; colleagues; covid-19; health; needs; pandemic; resources; stress; support; workers
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        item: #5324 of 7819
          id: cord-323074-u3bs5sj0
      author: Garcia, L. P.
       title: ESTIMATING UNDERDIAGNOSIS OF COVID-19 WITH NOWCASTING AND MACHINE LEARNING: EXPERIENCE FROM BRAZIL
        date: 2020-07-02
       words: 3798
      flesch: 49
     summary: The average age among confirmed cases was higher than among discarded cases. To help overcome this challenge, the present study aimed to analyze the underdiagnosis of COVID-19 cases, through nowcasting with machine learning, in a South of Brazil capital city.
    keywords: cases; covid-19; data; license; medrxiv; nowcasting; number; preprint; underdiagnosis
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        item: #5325 of 7819
          id: cord-323092-j2u0ny2u
      author: Crosby, James C.
       title: COVID‐19: A review of therapeutics under investigation
        date: 2020-04-19
       words: 3905
      flesch: 44
     summary: There is another single ongoing observational trial examining the efficacy of anti-SARS-CoV-2 inactivated convalescent plasma in COVID-19 patients, the results of which remain to be seen. Some anecdotal evidence is emerging regarding its use in COVID-19 patients.
    keywords: chloroquine; convalescent; coronavirus; cov-2; covid-19; disease; patients; plasma; sars; treatment; use
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        item: #5326 of 7819
          id: cord-323103-55yjl25x
      author: Waitzkin, Howard
       title: Confronting the Upstream Causes of COVID-19 and Other Epidemics to Follow
        date: 2020-08-03
       words: 2142
      flesch: 39
     summary: These organizations have suffered cutbacks in public funding but have received increased support from international financial institutions and private philanthropies that emphasize the downstream effects rather than upstream causes of infectious diseases. Partly due to such financial support, international and national health organizations almost always promote reductionist initiatives that focus on so-called magic bullets such as vaccines and antiviral medications, as well as behavioral change at the level of individuals, rather than upstream causes.
    keywords: agriculture; capitalist; causes; covid-19; health; pandemic
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        item: #5327 of 7819
          id: cord-323137-8b06u7kt
      author: Chern, Alexander
       title: Dissemination of Information During Public Health Crises: Early COVID‐19 Data From The Laryngoscope
        date: 2020-10-06
       words: 3346
      flesch: 36
     summary: Outcomes of interest extracted from the database search and internal data from The Laryngoscope included 1) number of COVID-19 publications during the first 4 months of the COVID-19 pandemic, 2) number of publications pertaining to historic respiratory pandemics of the 20th and 21st century during the first 2 years of each pandemic, 3) COVID-19 submission trends (i.e., number of submissions, topic, publication type, and status of publication) during the first 4 months of the COVID-19 pandemic, and 4) publication speed before and during the COVID-19 pandemic. Laryngoscope 00: 2020 Chern and Selesnick: COVID-19 Publications From The Laryngoscope
    keywords: covid-19; laryngoscope; pandemic; publication; submissions; time
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        item: #5328 of 7819
          id: cord-323141-6z750avb
      author: Kuroda, Naoto
       title: Demand for BCG Vaccine Due to Unproven Claims of its Role in Preventing COVID-19 Is Causing Shortages of Vaccines for Infants in Japan
        date: 2020-12-05
       words: 1762
      flesch: 47
     summary: SARS-CoV-2 infection in a pediatric department in Milan: a logistic rather than a clinical emergency Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn Antibodies in infants born to mothers with COVID-19 pneumonia Coronavirus infections in children including COVID-19 an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children Guidelines for pregnant women with suspected SARS-CoV-2 infection Can a century-old TB vaccine steel the immune system against the new coronavirus? Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Immune boost against the corona virus [Max-Planck-GesellSchaft web site The environment and disease: association or causation Opinion about effectiveness of BCG vaccine against COVID-19 Apprehension regarding BCG shortage led the Japanese Society for Vaccinology to officially state that it does not recommend the use of BCG vaccine for the prevention of COVID-19.
    keywords: bcg; care; covid-19; data; infection
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        item: #5329 of 7819
          id: cord-323200-xnr02xq3
      author: Mansuri, Farah M.A.
       title: Situation analysis and an insight into assessment of pandemic COVID-19
        date: 2020-04-08
       words: 1306
      flesch: 48
     summary: It is imperative to identify pandemic severity index to tackle the situation accordingly. Pandemic severity index should be assessed in the early phase of the outbreak by taking into account transmissibility, seriousness of clinical course and impact of pandemic on health care and societies.
    keywords: cases; covid-19; pandemic; severity
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        item: #5330 of 7819
          id: cord-323225-ou7pppum
      author: Mondal, R. N.
       title: Socio-demographic, clinical, hospital admission and oxygen requirement characteristics of COVID-19 patients of Bangladesh
        date: 2020-08-16
       words: 3353
      flesch: 56
     summary: key: cord-323225-ou7pppum authors: Mondal, R. N.; Razzak Sarker, M. A.; Das, A.; Ahsan, M. A. K.; Jahan, S. M. S.; Sultana, A.; Sultana, J.; Rani, M. title: Socio-demographic, clinical, hospital admission and oxygen requirement characteristics of COVID-19 patients of Bangladesh date: 2020-08-16 journal: nan DOI: 10.1101/2020.08.14.20175018 sha: doc_id: 323225 cord_uid: ou7pppum Abstract Background: Clinical presentation hospital admission and outcome of COVID-19 pandemic are different from one country to another. Conclusion: COVID-19 patients were mostly male health worker.
    keywords: covid-19; hospital; license; medrxiv; patients; preprint; study; symptoms
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        item: #5331 of 7819
          id: cord-323274-vhcvbiqm
      author: Gansevoort, Ron T.
       title: CKD is a key risk factor for COVID-19 mortality
        date: 2020-08-26
       words: 1245
      flesch: 41
     summary: This analysis, which includes data for more than 17 million people in the UK, suggests that patients with chronic kidney disease are at higher risk than those with other known risk factors, including chronic heart and lung disease. This analysis, which includes data for more than 17 million people in the UK, suggests that patients with chronic kidney disease are at higher risk than those with other known risk factors, including chronic heart and lung disease.
    keywords: covid-19; patients; risk
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        item: #5332 of 7819
          id: cord-323314-y3k9dntf
      author: Aggarwal, Sandeep
       title: Obesity and Metabolic Surgery Society of India (OSSI) Recommendations for Bariatric and Metabolic Surgery Practice During the COVID-19 Pandemic
        date: 2020-08-22
       words: 2792
      flesch: 43
     summary: Obes Surg The impact of COVID-19 pandemic on obesity and bariatric surgery Safer through surgery: American Society for Metabolic and Bariatric Surgery statement regarding metabolic and bariatric surgery during the COVID-19 pandemic Recommendations for metabolic and bariatric surgery during the COVID-19 pandemic from IFSO Joint Statement: roadmap for resuming elective surgery after COVID-19 pandemic SAGES and EAES recommendations for minimally invasive surgery during COVID-19 pandemic Surgical practice recommendations for minimal access surgeons during COVID 19 pandemic-Indian inter society directives Bariatric surgical practice during the initial phase of COVID-19 outbreak Bariatric and metabolic surgery during and after the COVID-19 pandemic: DSS recommendations for management of surgical candidates and postoperative patients and prioritisation of access to surgery A structured approach for safely reintroducing bariatric surgery in a COVID-19 environment published online ahead of print Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 cases Conversion of operating theatre from positive to negative pressure environment Surgery in COVID-19 patients: operational directives Consensus guidelines for managing the airway in patients with COVID −19: guidelines from the Difficult Airway Society, the Association of Anaesthetists the Intensive Care Society, the Faculty of Intensive Care Medicine and the Royal College of Anaesthetists COVID operation theatre-advisory and position statement of Indian Society of Anaesthesiologists COVID-19 & the general surgical department-measures to reduce spread of SARS-COV-2 among surgeons Detecting hepatitis B virus in surgical smoke emitted during laparoscopic surgery Is there a role for ERAS program implementation to restart bariatric surgery after the peak of COVID-19 pandemic? Recommendations for surgery during the novel coronavirus (COVID-19) epidemic Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations In view of the above and considering obesity and bariatric surgery to be of equal importance as other chronic lifethreatening diseases and cancer, the Obesity and Metabolic Surgery Society of India (OSSI) decided to frame recommendations which will help bariatric surgeons to prepare for the possible recommencement of bariatric surgery in the near future.
    keywords: bms; covid-19; obesity; pandemic; patients; recommendations; risk; surgery
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        item: #5333 of 7819
          id: cord-323327-08p122lw
      author: van de Veerdonk, Frank L.
       title: Blocking IL-1 to prevent respiratory failure in COVID-19
        date: 2020-07-18
       words: 3023
      flesch: 36
     summary: Studies that recruited in total almost 2000 patients demonstrated that although anakinra did not reduce the overall all-cause mortality, survival was increased in the subgroup of sepsis patients with features of MAS (ferritin elevations in excess of 2000 ng/ml, coagulopathy, and liver enzyme elevations) Yearb Intensive Care Emerg Med Coagulation abnormalities and thrombosis in patients with COVID-19 Kallikrein-kinin blockade in patients with COVID-19 to prevent acute respiratory distress syndrome Endothelial cell infection and endotheliitis in COVID-19 Cytotoxic therapy for severe avian influenza A (H5N1) infection A case of macrophage activation syndrome successfully treated with anakinra Macrophage activation syndrome treated with anakinra Benefit of anakinra in treating pediatric secondary hemophagocytic lymphohistiocytosis Interleukin-1 receptor blockade is associated with reduced mortality in sepsis patients with features of macrophage activation syndrome: reanalysis of a prior phase III trial Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial.
    keywords: anakinra; covid-19; il-1; mas; patients; sars; syndrome
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        item: #5334 of 7819
          id: cord-323363-mcmce24i
      author: Wong, Raymond L.M.
       title: COVID-19 Pandemic: Ways Forward
        date: 2020-04-29
       words: 737
      flesch: 43
     summary: China and the United States have already started Phase 1 studies respectively in early to mid-March 2020 for COVID-19 vaccines. (Preprint from medRxiv) COVID-19: special precautions in ophthalmic practice and FAQs on personal protection and mask selection Stepping up infection control measures in ophthalmology during the novel coronavirus outbreak: an experience from Hong Kong
    keywords: covid-19; ophthalmology; vaccines
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        item: #5335 of 7819
          id: cord-323398-4zvs7f6e
      author: Groshkova, Teodora
       title: Will the Current COVID-19 Pandemic Impact on Long-Term Cannabis Buying Practices?
        date: 2020-05-29
       words: 828
      flesch: 50
     summary: The COVID-19 pandemic is impacting on all areas of life and for an agency responsible for monitoring drug markets in Europe two important questions are: is the current pandemic affecting the availability and use of drugs? EU drug markets report.
    keywords: cannabis; covid-19; drug
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        item: #5336 of 7819
          id: cord-323421-67r1qmc9
      author: Liao, Yunfei
       title: Clinical Characteristics and Risk factors for developed COVID-19 patients transferring to designated hospital from Jianghan Fangcang shelter Hospital: a retrospective, observational study
        date: 2020-04-24
       words: 3724
      flesch: 52
     summary: Therefore, a retrospective review of overall medical record was performed in Fangcang shelter hospital of Jianghan, which received the largest number of patients among Fangcang shelter hospitals in Wuhan. Fangcang shelter hospitals have been applied in COVID-19 to ease ongoing shortage of medical resources in Wuhan since February 2020.
    keywords: covid-19; fangcang; hospital; patients; preprint; shelter; study; type
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        item: #5337 of 7819
          id: cord-323424-86wh4u6l
      author: Santos, M. M.
       title: Survival and predictors of deaths of patients hospitalised due to COVID-19 from a retrospective and multicentre cohort study in Brazil
        date: 2020-09-07
       words: 3748
      flesch: 41
     summary: Ministério da Saúde Nonparametric estimation from incomplete samples Survival analysis II: Cox regression Survival analysis of elderly patients in intensive care units Risk factors for disease severity, unimprovement, and mortality in COVID-19 patients in Wuhan Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study Health inequity during the COVID-19 pandemic: a cry for ethical global leadership Using social and behavioural science to support COVID-19 pandemic response Risk assessment of progression to severe conditions for patients with COVID-19 pneumonia: a single-center retrospective study. However, it would be necessary to develop prospective cohort studies to monitor, mainly, the changes in the clinical signs of patients with COVID-19 and their impact on the survival of hospitalised patients and how this interferes with the length of stay in the ICU.
    keywords: covid-19; death; disease; hospital; patients; risk; study; survival
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        item: #5338 of 7819
          id: cord-323439-z6rghua1
      author: Sampaio, Pedro Paulo N.
       title: Rescue Venoarterial Extracorporeal Membrane Oxygenation After Cardiac Arrest in COVID-19 Myopericarditis: A Case Report
        date: 2020-09-30
       words: 1555
      flesch: 24
     summary: We describe the first case of fulminant COVID-19 myopericarditis and tamponade successfully treated with venoarterial ECMO, neutralizing antibodies and anti-inflammatory therapies, after recovery from cardiac arrest. Our report illustrates the importance of appropriate supportive measures in fulminant COVID-19 myopericarditis, particularly the potential role of timely venoarterial ECMO support for circulatory shock following recovery from cardiac arrest.
    keywords: arrest; covid-19; ecmo
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        item: #5339 of 7819
          id: cord-323446-w2ci1bfr
      author: Pan, Feng
       title: Time Course of Lung Changes On Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Pneumonia
        date: 2020-02-13
       words: 2830
      flesch: 52
     summary: Based on quartiles of patients from day 0 to day 26 involvement, 4 stages of lung CT were defined: Stage 1 (0-4 days): ground glass opacities (GGO) in 18/24 (75%) patients with the total CT score of 2±2; (2)Stage-2 (5-8d days): increased crazy-paving pattern 9/17 patients (53%) with a increase in total CT score (6±4, p=0.002); (3) Stage-3 (9-13days): consolidation 19/21 (91%) patients with the peak of total CT score (7±4); (4) Stage-4 (≥14 days): gradual resolution of consolidation 15/20 (75%) patients with a decreased total CT score (6±4) without crazy-paving pattern.
    keywords: covid-19; days; patients; pneumonia; total
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        item: #5340 of 7819
          id: cord-323468-xn7anxj6
      author: Olloquequi, Jordi
       title: COVID‐19 Susceptibility in chronic obstructive pulmonary disease
        date: 2020-08-11
       words: 4159
      flesch: 37
     summary: All rights reserved 70 Immune Dysfunction in Patients with Chronic Obstructive Pulmonary Disease Amplification of inflammation in emphysema and its association with latent adenoviral infection Impaired phagocytosis of nontypeable Haemophilus influenzae by human alveolar macrophages in chronic obstructive pulmonary disease Impaired alveolar macrophage response to Haemophilus antigens in chronic obstructive lung disease Dysregulated Functions of Lung Macrophage Populations in COPD Accumulation of dendritic cells and increased CCL20 levels in the airways of patients with chronic obstructive pulmonary disease Acute effects of tobacco smoke on human airway dendritic cells in vivo Lung dendritic cell expression of maturation molecules increases with worsening chronic obstructive pulmonary disease Deficient pulmonary IFN-beta expression in COPD patients Interferon-beta 1a and SARS coronavirus replication Interferon-beta and interferon-gamma synergistically inhibit the replication of severe acute respiratory syndrome-associated coronavirus Polymeric immunoglobulin receptor down-regulation in chronic obstructive pulmonary disease. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) recognizes COPD patients amongst the worst affected by COVID-19 11 .
    keywords: cells; copd; coronavirus; covid-19; disease; infection; lung; patients; risk
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        item: #5341 of 7819
          id: cord-323471-stajtsbf
      author: Kristoffersen, ES
       title: Hospital-based headache care during the Covid-19 pandemic in Denmark and Norway
        date: 2020-10-29
       words: 3857
      flesch: 47
     summary: It is not known how the management of headache patients was affected by the lockdown during the pandemic. Overall, 54% reported that the standard of care was worse for headache patients during the pandemic.
    keywords: care; covid-19; denmark; headache; lockdown; norway; pandemic; patients
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        item: #5342 of 7819
          id: cord-323482-kk8iyavj
      author: Muller, Researcher Ashley Elizabeth
       title: The mental health impact of the covid-19 pandemic on healthcare workers, and interventions to help them: a rapid systematic review
        date: 2020-09-01
       words: 5343
      flesch: 32
     summary: what next? Protect our healthcare workers The impact of the covid-19 pandemic on mental health of health care workers: protocol for a rapid systematic review A systematic and living evidence map on COVID-19 AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both CASP checklist for qualitative research GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables COVID19 pandemic impacts on anxiety of French urologist in training: Outcomes from a national survey COVID-19 outbreak situation and its psychological impact among surgeon in training in France Fear and Practice Modifications among Dentists to Combat Novel Coronavirus Disease (COVID-19) Outbreak Working in the emergency and inpatient COVID-19 special wards: a different experience for Iranian psychiatric trainees amid the outbreak: Running title: Experience of Iranian psychiatric trainees in COVID-19 special wards Psychological Impact and Coping Strategies of Frontline Medical Staff in Hunan Between A cross-sectional study on mental health among health care workers during the outbreak of Corona Virus Disease A Study of Basic Needs and Psychological Wellbeing of Medical Workers in the Fever Clinic of a Tertiary General Hospital in Beijing during the COVID-19 Outbreak Mental health care for medical staff in China during the COVID-19 outbreak.
    keywords: covid-19; health; healthcare; interventions; outbreak; pandemic; psychological; studies; study; workers
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        item: #5343 of 7819
          id: cord-323489-ro7kbnu3
      author: Arenas, María Dolores
       title: Protection of nephrology health professionals during the COVID-19 pandemic
        date: 2020-10-06
       words: 4139
      flesch: 39
     summary: This exposure can result from contact with other patients or with co-workers. There are a number of reasons why the protection of healthcare professionals has to be one of the main objectives in the SARS-CoV-2 pandemic: 1) They are necessary to guarantee the continuity of care; 2) They have a high risk of contagion due to their front-line exposure to infected patients; and 3)
    keywords: coronavirus; covid-19; equipment; healthcare; hospital; patients; professionals; risk; staff
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        item: #5344 of 7819
          id: cord-323497-9km0i816
      author: Jella, Tarun K.
       title: Geospatial Mapping of Orthopaedic Surgeons Age 60 and Over and Confirmed Cases of COVID-19
        date: 2020-04-23
       words: 2938
      flesch: 41
     summary: Therefore, the purposes of the present study are (1) to determine the geographic distribution of older orthopaedic surgeons in the U.S., (2) to compare the distribution with those of other surgical specialties, and (3) to compare this distribution with the spread of COVID-19 in the U.S. D emographic statistics for 2018 were extracted from the most recent State Physician Workforce Data Reports published by the Association of American Medical Colleges (AAMC) to identify the proportion of practicing orthopaedic surgeons ‡60 years of age in each state 13 . While the high proportion of orthopaedic surgeons ‡60 years of age may prove problematic during the COVID-19 pandemic, there are further implications for workforce management and patient access to care in the future because of the aging of this demographic group and a potentially critical gap in the total number of practicing orthopaedic surgeons in the U.S. 21 .
    keywords: age; covid-19; orthopaedic; providers; surgeons; workforce; years
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        item: #5345 of 7819
          id: cord-323503-l5skiu2l
      author: Neri, E.
       title: Structured reporting of chest CT in COVID-19 pneumonia: a consensus proposal
        date: 2020-08-12
       words: 4294
      flesch: 38
     summary: pneumonia Chest CT features of COVID-19 in Coronavirus disease 2019 (COVID-19) CT findings: a systematic review and meta-analysis Covid-19: round and oval areas of groundglass opacity Baltoma (bronchus-associated lymphoid tissue lymphoma) presenting as enlarging ground glass opacities Bronchioloalveolar carcinoma and ground glass opacities Ground glass opacities as indolent stage IV lung adenocarcinoma Reversed halo sign on 3D CT in COVID-19 Crazy paving AIDS-related Kaposi sarcoma of the lung presenting with a crazypaving pattern on high-resolution CT: imaging and pathologic findings Big data, artificial intelligence, and structured reporting Adding value in radiology reporting Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Acute pulmonary embolism in COVID-19 patients on CT angiography and relationship to Ddimer levels Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT Well-aerated lung on admitting chest CT to predict adverse outcome in COVID-19 pneumonia [10, 11] , and the RSNA expert consensus statement on reporting chest CT findings related to COVID-19, endorsed also by the Society of Thoracic Radiology and
    keywords: chest; covid-19; data; imaging; patients; radiology; report; reporting; round
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        item: #5346 of 7819
          id: cord-323507-u28g423o
      author: Ofosu-Poku, Rasheed
       title: Preparing a young palliative care unit for the COVID-19 pandemic in a teaching hospital in Ghana
        date: 2020-06-24
       words: 1458
      flesch: 52
     summary: Each day had a lists of tasks to be accomplished which included patient care, preparing presentations, discussing studies to be undertaken, and reviewing strategies to expand palliative care within the hospital. The team now has three nurses trained in palliative care who are dedicated only to performing palliative care-related tasks.
    keywords: care; health; palliative; team
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        item: #5347 of 7819
          id: cord-323538-9dlr6kqh
      author: Malard, Florent
       title: COVID-19 outcomes in patients with hematologic disease
        date: 2020-05-06
       words: 1604
      flesch: 41
     summary: We observed an overrepresentation of patients with MM in our cohort (although MM is not overrepresented in our department), suggesting that such patients are particularly vulnerable, owning to the immunosuppression associated with the disease and its treatment, in particular steroids. key: cord-323538-9dlr6kqh authors: Malard, Florent; Genthon, Alexis; Brissot, Eolia; van de Wyngaert, Zoe; Marjanovic, Zora; Ikhlef, Souhila; Banet, Anne; Lapusan, Simona; Sestilli, Simona; Corre, Elise; Paviglianiti, Annalisa; Adaeva, Rosa; M.’Hammedi-Bouzina, Fella; Labopin, Myriam; Legrand, Ollivier; Dulery, Rémy; Mohty, Mohamad title: COVID-19 outcomes in patients with hematologic disease date: 2020-05-06 journal:
    keywords: covid-19; hematologic; infection; patients
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        item: #5348 of 7819
          id: cord-323540-7b2mt1a8
      author: García, Leidy Y.
       title: Contingent assessment of the COVID-19 vaccine
        date: 2020-06-25
       words: 4015
      flesch: 46
     summary: The Keywords: COVID-19; SARS-CoV-2; vaccine; acceptance; health economics; contingent valuation The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as a pandemic coronavirus disease 2019 (COVID- 19) has had a negative impact on people's health and life and on economies around the world. The vaccine is expected to be available free of charge to at least the poorest people with financing from the governments of each country, while the richest people could voluntarily seek vaccines in private clinics.
    keywords: covid-19; covid-19 vaccine; health; individual; vaccine; value; wtp
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        item: #5349 of 7819
          id: cord-323570-jpicmqpq
      author: Dambha-Miller, Hajira
       title: Drug treatments affecting ACE2 in COVID-19 infection: a systematic review protocol
        date: 2020-07-15
       words: 2405
      flesch: 43
     summary: Methodological quality of included animal studies will be assessed using the SYRCLE risk of bias tool. ACE2 expression may be associated with COVID-19 infection and mortality rates.
    keywords: ace2; covid-19; data; drug; expression; review; studies
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        item: #5350 of 7819
          id: cord-323582-7y8pt72r
      author: Ahamad, Martuza
       title: A Machine Learning Model to Identify Early Stage Symptoms of SARS-Cov-2 Infected Patients
        date: 2020-06-20
       words: 4458
      flesch: 51
     summary: • Identification of the significant symptoms of COVID-19 patients by analyzing their association using five different machine learning approaches. We calculated the coefficient values for each feature that are significant for COVID-19 patients.
    keywords: accuracy; age; covid-19; data; features; infection; machine; patients; symptoms
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        item: #5351 of 7819
          id: cord-323590-m4jsu1q5
      author: Ortiz de Landazuri, Iñaki
       title: Manufacturing and Management of CAR T-Cell Therapy in “COVID-19’s Time”: Central Versus Point of Care Proposals
        date: 2020-10-15
       words: 4344
      flesch: 35
     summary: Nevertheless, delaying cell therapy as a consequence of the COVID-19 pandemic could be fatal for the majority of patients with relapsed/refractory malignancies. There exist strict regulations associateds with cell therapy where personnel who develop living drugs must work under sterile and GMP conditions.
    keywords: car; car t; cell; covid-19; manufacturing; pandemic; patients; receptor; therapy
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        item: #5352 of 7819
          id: cord-323591-8r30lsq8
      author: Martinez, Edson Zangiacomi
       title: Long-term forecasts of the COVID-19 epidemic: a dangerous idea
        date: 2020-08-26
       words: 2354
      flesch: 41
     summary: London: Imperial College COVID-19 Response Team Special report: The simulations driving the world's response to COVID-19 Predictive mathematical models of the COVID-19 pandemic: underlying principles and value of projections Estimation and prediction of COVID-19 cases in Brazilian metropolises Forecasting the rate of cumulative cases of COVID-19 infection in Northeast Brazil: a Boltzmann function-based modeling study Mathematical Models in Epidemiology Middle East respiratory syndrome coronavirus (MERS-CoV) nosocomial outbreak in South Korea: insights from modeling Painel de casos de doença pelo coronavírus 2019 (COVID-19) no Brasil. Brasília: Ministério da Saúde Short-term forecasting of daily COVID-19 cases in Brazil by using the Holt's model Asymptotic estimates of SARS-CoV-2 infection counts and their sensitivity to stochastic perturbation Contact tracing assessment of COVID-19 transmission dynamics in Taiwan and risk at different exposure periods before and after symptom onset Risk factors associated with COVID-19 infection: a retrospective cohort study based on contacts tracing Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany Value investing: from Graham to Buffett and beyond The authors declare no conflicts of interest.
    keywords: cases; covid-19; disease; epidemic; model; number
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        item: #5353 of 7819
          id: cord-323603-99d0wv1h
      author: Nunez Garcia, B.
       title: Real-world data: Cancer and SARS-CoV-2 infection
        date: 2020-09-30
       words: 1540
      flesch: 50
     summary: The SARS-CoV-2 pandemic had a profound negative effect on the overall diagnostic output of the centralized molecular diagnostics for cancer patients and high-risk individuals in Serbia. We report data from our study, comparing cancer patients to an age-and sex-matched non-cancer cohort.
    keywords: cancer; covid-19; infection; patients; sars
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        item: #5354 of 7819
          id: cord-323616-53kksp5w
      author: Wright, L.
       title: What predicts adherence to COVID-19 government guidelines? Longitudinal analyses of 51,000 UK adults.
        date: 2020-10-21
       words: 6780
      flesch: 47
     summary: We find evidence that increased confidence in government to tackle the pandemic is longitudinally related to higher compliance, but little evidence that factors such as mental health and wellbeing, worries about future adversities, and social isolation and loneliness are related to changes in compliance. Further cross-sectional and longitudinal studies show that beliefs about the efficacy of COVID-19 measures are associated with higher compliance 12, 13 .
    keywords: compliance; covid-19; health; license; medrxiv; models; preprint; time; version
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        item: #5355 of 7819
          id: cord-323631-r31sfq90
      author: Edul, Vanina Siham Kanoore
       title: Microcirculation alterations in severe COVID-19 pneumonia
        date: 2020-10-17
       words: 788
      flesch: 35
     summary: Values of COVID-19 patients were Microvascular thrombosis: experimental and clinical implications Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19 Pulmonary and systemic involvement of COVID-19 assessed by ultrasound-guided minimally invasive autopsy Postmortem Examination of Patients With COVID-19 Microvascular alterations in patients with SARS-COV-2 severe pneumonia Quantitative assessment of the microcirculation in healthy volunteers and in patients with septic shock The microcirculation image quality score: development and preliminary evaluation of a proposed approach to grading quality of image acquisition for bedside videomicroscopy Effect of a Resuscitation Strategy Targeting Peripheral Perfusion Status vs Serum Capillary Recruitment in Response to Tissue Hypoxia and Its Dependence on Red Blood Cell Deformability Angiopoietin-2 as a marker of endothelial activation is a good predictor factor for intensive care unit admission of COVID-19 patients Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy: a two-centre descriptive study The respective institutional review boards approved this study and waived patient informed consent. COVID-19 patients showed an altered tissue perfusion.
    keywords: covid-19; microcirculation; patients
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        item: #5356 of 7819
          id: cord-323633-d0w8oqp8
      author: Banda, J. M.
       title: Long-term patient-reported symptoms of COVID-19: an analysis of social media data
        date: 2020-08-01
       words: 999
      flesch: 43
     summary: Patients reported additional symptoms, including palpitations and insomnia/sleep disorders potentially attributable to neuro-psychological, cardiac or respiratory sequelae. There have been reports of persistent symptoms after confirmed infections on patients even after three months of initial recovery.
    keywords: covid-19; symptoms; term
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        item: #5357 of 7819
          id: cord-323647-q67fa0m3
      author: Misra, Durga Prasanna
       title: Benefits and adverse effects of hydroxychloroquine, methotrexate and colchicine: searching for repurposable drug candidates
        date: 2020-09-02
       words: 6153
      flesch: 32
     summary: In this French RCT (the BBQ trial), patients with recurrent pregnancy loss shall be treated with HCQ 400 mg daily or placebo starting pre-conception until the 10 th week of pregnancy, with the objective of assessing whether treatment improves pregnancy outcomes in such patients [18] . THerapy in ST-Segment Elevation MYocardial InfarctionS: a randomized double-blind, placebocontrolled trial (TETHYS Trial) Low-dose methotrexate for the prevention of atherosclerotic events Colchicine as an anti-inflammatory and cardioprotective agent Colchicine revisited The NLRP3 inflammasome and the emerging role of colchicine to inhibit atherosclerosis-associated inflammation Colchicine improves survival, left ventricular remodeling, and chronic cardiac function after acute myocardial infarction Effects of colchicine on atherosclerotic plaque stabilization: a multimodality imaging study in an animal model Colchicine reduces platelet aggregation by modulating cytoskeleton rearrangement via inhibition of cofilin and LIM domain kinase 1 Can the thiol/disulfide imbalance be a predictor of colchicine resistance in familial mediterranean fever? Colchicine therapy and plaque stabilization in patients with acute coronary syndrome: a CT coronary angiography study Effect of shortterm colchicine treatment on endothelial function in patients with coronary artery disease Colchicine as a novel therapy for suppressing chemokine production in patients with an acute coronary syndrome: a pilot study The Low Dose Colchicine after Myocardial Infarction (LoDoCo-MI) study: a pilot randomized placebo controlled trial of colchicine following acute myocardial infarction The effect of low-dose colchicine in patients with stable coronary artery disease: the LoDoCo2 trial rationale, design, and baseline characteristics COLIN trial: value of colchicine in the treatment of patients with acute myocardial infarction and inflammatory response Efficacy and safety of low-dose colchicine after myocardial infarction Role of colchicine in stroke prevention: an updated meta-analysis The role of colchicine in treating postoperative and post-catheter ablation atrial fibrillation Comparative transcriptome analysis to elucidate the therapeutic mechanism of colchicine against atrial fibrillation The effect of colchicine on the echocardiographic constrictive physiology after coronary artery bypass graft surgery Colchicine attenuates renal injury in a model of hypertensive chronic kidney disease Effects of colchicine on renal fibrosis and apoptosis in obstructed kidneys Effectiveness of colchicine therapy in 4 cases of retroperitoneal fibrosis associated with autoinflammatory diseases Use of colchicine to prevent recurrence of ear keloids.
    keywords: colchicine; covid-19; disease; drugs; effects; hcq; hydroxychloroquine; methotrexate; patients; placebo; risk; treatment; trial
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        item: #5358 of 7819
          id: cord-323661-rss9litb
      author: Gressenberger, Paul
       title: Significant increase in the incidence of high-risk pulmonary embolism during the COVID-19 shutdown: the pandemic response causes serious collateral consequences
        date: 2020-10-06
       words: 1442
      flesch: 40
     summary: For high risk patients, rapid systemic fibrinolytic therapy is recommended to reduce the risk of cardiovascular collapse and early death (7, 8) . We compared percentages of patients admitted with high risk PE between the shutdown period (March 16 to April 30, 2020) and two control periods when no pandemic was present: an earlier period during the same year (January 1 to February 15, 2020; control period 1) and a corresponding period during the previous year (March 16 to April 30, 2019; control period 2).
    keywords: covid-19; patients; period; risk
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        item: #5359 of 7819
          id: cord-323666-t7cshj05
      author: Cegolon, L.
       title: Nasal Disinfection for the Prevention and Control of COVID-19: A Scoping Review on Potential Chemo-preventive Agents.
        date: 2020-08-18
       words: 6192
      flesch: 41
     summary: Therefore, there are two issues with COVID- 19: high transmissibility of the virus and variable clinical pattern of the disease, which can range from pre-symptomatic/asymptomatic condition to life threatening pneumonia featured by severe acute respiratory syndrome (SARS) and hypercoagulable state The abstracts of the original articles were explored for the following terms: mechanism(s) of action, tolerability and any evidence of toxic effects or selection of resistant strains, whether the treatment was tested in vitro (in particular against SARS-CoV-2), or reached the clinical trials stage, or is currently marketed/promoted/sold.
    keywords: activity; control; coronavirus; cov-2; covid-19; human; infection; nasal; sars; system; treatment; virus
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        item: #5360 of 7819
          id: cord-323676-sp8kys0n
      author: Valensisi, Giovanni
       title: COVID-19 and Global Poverty: Are LDCs Being Left Behind?
        date: 2020-10-21
       words: 7126
      flesch: 44
     summary: Focusing on the US$3.20 per day poverty line, South Asia is likely to suffer by far the largest slump, entailing a rise of nearly 4 percentage points in the headcount ratio, equivalent to 74 million additional poor, compared with what would have occurred if the pre-COVID-19 growth forecasts had materialized (Fig. 4) . Finally, our estimates suggest that the pandemic will exert a more visible and widespread impact on global poverty measures according to the US$5.50 per day poverty line.
    keywords: countries; covid-19; day; economic; growth; headcount; imf; impact; line; people; poverty; poverty line; world
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        item: #5361 of 7819
          id: cord-323686-1bmpvmdd
      author: Vrdoljak, Eduard
       title: Cancer and COVID-19; how do we manage cancer optimally through a public health crisis?
        date: 2020-04-18
       words: 1070
      flesch: 37
     summary: The consequences of the lockdown measures and displacement of cancer awareness in the general population, as well as rapid and profound re-educations in many aspects of cancer care, could have significant impact on cancer outcomes, particularly in transitional countries such as Central and Eastern Europe (CEE) countries and in Low and Middle Income Countries (LMICs), where pre-COVID-19 we have already been experiencing significant challenges in delivering cancer control, with increasingly fragile cancer services and already stressed general healthcare systems. Denying that this downside exists will mean that we will be adding the lost lives of cancer patients to the COVID-19 death count toll.
    keywords: cancer; covid-19; patients
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        item: #5362 of 7819
          id: cord-323690-dp51djtz
      author: Arora, Alisha
       title: Understanding Coronaphobia
        date: 2020-09-06
       words: 3269
      flesch: 40
     summary: Various components and outcomes of COVID-19 fear have been reported such as functional impairment leading to hopelessness, suicidal ideation, and coping deficits (Lee, 2020) , fatal cognitions leading to association of COVID-19 with terminal end (Dubey et al., 2020; Viral misinformation Coronavirus Anxiety Scale: A brief mental health screener for COVID-19 related anxiety The Common-Sense Model of Self-Regulation (CSM): a dynamic framework for understanding illness self-management Progression of Mental Health Services during the COVID-19 Outbreak in China Google searches for the keywords of wash hands predict the speed of national spread of COVID-19 outbreak among 21 countries Why it's so hard not to touch your face.
    keywords: 2020; anxiety; coronaphobia; covid-19; fear; health; risk
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        item: #5363 of 7819
          id: cord-323695-jkik03lb
      author: Paolo, Gisondi
       title: Incidence rates of hospitalization and death from COVID-19 in patients with psoriasis receiving biological treatment: a Northern Italy experience
        date: 2020-11-05
       words: 1747
      flesch: 36
     summary: Despite a great effort has been made in retrieving COVID-19 patients, we acknowledge that there is still a possibility that we have missed important cases. Elevated plasma level of selective cytokines in COVID-19 patients reflect viral load and lung injury Associations between immune-suppressive and stimulating drugs and novel COVID-19-a systematic review of current evidence.
    keywords: cov-2; covid-19; patients; psoriasis
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        item: #5364 of 7819
          id: cord-323696-0lq8ql6n
      author: Bearman, Gonzalo
       title: Reflections on the COVID-19 Pandemic in the USA: Will We Better Prepared Next Time?
        date: 2020-05-20
       words: 1856
      flesch: 46
     summary: Public health systems must be adequately funded and staffed to address both present and future infectious diseases threats. The fragmentation, disparities in care and misaligned incentives do not provide a strong foundation for public health emergencies.
    keywords: covid-19; diseases; health; healthcare; pandemic; public
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        item: #5365 of 7819
          id: cord-323705-n2rec4i8
      author: Varatharaj, Aravinthan
       title: Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study
        date: 2020-06-25
       words: 5255
      flesch: 31
     summary: These complications are relatively uncommon, but such patients are often the most severely affected, neces sitating protracted intensive care admis sion and often resulting in poor outcomes. Neurologic manifestations of hospitalized patients with coronavirus disease Olfactory and gustatory dysfunctions as a clinical presentation of mildto moderate forms of the coronavirus disease (COVID19): a multicenter European study Selfreported olfactory and taste disorders in SARSCoV2 patients: a crosssectional study A first case of meningitis/ encephalitis associated with SARSCoronavirus2 COVID19associated acute hemorrhagic necrotizing encephalopathy: CT and MRI features Neurological associations of COVID19 Neurological manifestations of influenza infection in children and adults: results of a National British Surveillance Study Neurological complications during treatment of Middle East respiratory syndrome Coagulation disorders in coronavirus infected patients: COVID19, SARSCoV1, MERSCoV and lessons from the past Psychiatric and neuropsychiatric presentations associated with severe coronavirus infection: a systematic review and metaanalysis with comparison to the COVID19 pandemic Neurologic features in severe SARSCoV2 infection The Association of British Neurologists The British Association of Stroke Physicians.
    keywords: acute; cases; clinical; complications; covid19; data; health; infection; patients; psychiatric; status; stroke; study
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        item: #5366 of 7819
          id: cord-323743-hr23ux58
      author: Chen, Xiaofeng
       title: A diagnostic model for coronavirus disease 2019 (COVID-19) based on radiological semantic and clinical features: a multi-center study
        date: 2020-04-16
       words: 4077
      flesch: 42
     summary: Comparison of clinical features between the two groups of patients with and without COVID-19 is reported in Table 2 . The prediction models based on (i) clinical features (C model), (ii) radiological features (R model), and (iii) the combination of clinical features and radiological features (CR model) were developed.
    keywords: clinical; covid-19; features; imaging; model; patients; pneumonia
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        item: #5367 of 7819
          id: cord-323751-ofz4htdb
      author: Liu, Yuzhi
       title: Focusing on gastrointestinal symptoms in COVID-19 is far from enough
        date: 2020-05-18
       words: 823
      flesch: 43
     summary: key: cord-323751-ofz4htdb authors: Liu, Yuzhi; Xiang, Lingya; Deng, Kai title: Focusing on gastrointestinal symptoms in COVID-19 is far from enough date: 2020-05-18 journal: Gastroenterology DOI: 10.1053/j.gastro.2020.05.043 sha: doc_id: 323751 cord_uid: ofz4htdb nan We had great interest in the article by Yael R et al In comparison with the other reports on this topic [2, 3] , this case-control study can provide more significance and credibility owing to the correction of baseline status for gastrointestinal symptoms in non-COVID-19 patients.
    keywords: covid-19; non
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        item: #5368 of 7819
          id: cord-323766-oyyj35bl
      author: Parker, Michael J
       title: Ethics of instantaneous contact tracing using mobile phone apps in the control of the COVID-19 pandemic
        date: 2020-05-04
       words: 4598
      flesch: 48
     summary: key: cord-323766-oyyj35bl authors: Parker, Michael J; Fraser, Christophe; Abeler-Dörner, Lucie; Bonsall, David title: Ethics of instantaneous contact tracing using mobile phone apps in the control of the COVID-19 pandemic date: 2020-05-04 journal: J Med Ethics DOI: 10.1136/medethics-2020-106314 sha: doc_id: 323766 cord_uid: oyyj35bl In this paper we discuss ethical implications of the use of mobile phone apps in the control of the COVID-19 pandemic. To address this problem, many countries around the world have deployed or are developing mobile phone apps capable of supporting instantaneous contact tracing.
    keywords: app; contact; covid-19; health; people; phone; use
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        item: #5369 of 7819
          id: cord-323775-sonsrf5b
      author: Franchini, Linda
       title: Mental Health Services For Mood Disorder Outpatients In Milan During COVID-19 Outbreak: the experience of the health care providers at San Raffaele Hospital
        date: 2020-07-21
       words: 1645
      flesch: 31
     summary: Considering that this is the first experience of such a collective social trauma in Italy, no analyses have focused on the potentially negative role of quarantine restrictions on mood disorder patients yet. The potential negative role of quarantine restriction on mood disorder patients depends on the high susceptibility to lifestyle-mediated disturbances of biological and social rhythms (Wang et al., 2019) .
    keywords: disorder; frustration; mood; patients; quarantine
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        item: #5370 of 7819
          id: cord-323793-c69joaqs
      author: Palmieri, V.
       title: Can graphene take part in the fight against COVID-19?
        date: 2020-05-07
       words: 2814
      flesch: 37
     summary: A review of the 2019 novel coronavirus (COVID-19) Revisiting the dangers of the coronavirus in the ophthalmology practice Graphene based biosensors-accelerating medical diagnostics to new-dimensions Engineering Optical Absorption in Graphene and Other 2D Materials: Advances and Applications Graphene oxide touches blood:: In vivo interactions of bio-coronated 2D materials, Nanoscale Horizons Bacteria Meet Graphene: Modulation of Graphene Oxide Nanosheet Interaction with Human Pathogens for Effective Antimicrobial Therapy The graphene oxide contradictory effects against human pathogens Low cost synthesis of reduced graphene oxide using biopolymer for influenza virus sensor Ultrasensitive electrochemical immunoassay for avian influenza subtype H5 using nanocomposite Silver nanoparticles coated graphene electrochemical sensor for the ultrasensitive analysis of avian influenza virus H7 Protein degradation and RNA efflux of viruses photocatalyzed by graphene-tungsten oxide composite under visible light irradiation Modified cyclodextrins as broad-spectrum antivirals Membrane Protein of Human Coronavirus NL63 Is Responsible for Interaction with the Adhesion Receptor Size-dependent inhibition of herpesvirus cellular entry by polyvalent nanoarchitectures Highly efficient multivalent 2D nanosystems for inhibition of orthopoxvirus particles The future development of bacteria fighting medical devices: the role of graphene oxide The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 Receptor Binding Domain undergoes conformational change upon heparin binding Graphenebased Hotplate for the Capturing and Destruction of the Herpes Simplex Virus Type Multisite inhibitors for enteric coronavirus: antiviral cationic carbon dots based on curcumin Synergistic antiviral effect of curcumin functionalized graphene oxide against respiratory syncytial virus infection Functionalized nanographene sheets with high antiviral activity through synergistic electrostatic and hydrophobic interactions Virus Capture and Destruction by Label-Free Graphene Oxide for Detection and Disinfection Applications Herpes simplex virus type-1 attachment inhibition by functionalized graphene oxide Antiviral activity of graphene oxide: how sharp edged structure and charge matter Graphene oxide and lipid membranes: interactions and nanocomposite structures Reduced graphene oxide directed self-assembly of phospholipid monolayers in liquid and gel phases Antiviral Activity of Graphene-Silver Nanocomposites against Non-Enveloped and Enveloped Viruses Graphene quantum dots based systems as HIV inhibitors Hypericin-loaded graphene oxide protects ducks against a novel duck reovirus Pristine graphene is a single-atom-thick sheet of hexagonally arranged carbon atoms, graphene oxide (GO) is its oxidized counterpart.
    keywords: activity; coronavirus; covid-19; graphene; materials; oxide; surface; virus; viruses
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        item: #5371 of 7819
          id: cord-323794-p3zjxo1h
      author: Malik, A. A.
       title: Determinants of COVID-19 Vaccine Acceptance in the U.S.
        date: 2020-05-24
       words: 3692
      flesch: 46
     summary: There were notable geographic differences in COVID-19 vaccine acceptance with DHHS Region 8-Denver having an acceptance rate of over 75% (total sample in region, N = 20; number of participants within sample that would accept COVID-19 vaccine, n = 16) while Region 2-New York (N = 51; n = 22), and Region 5-Chicago (N = 23; n = 9) had an acceptance rate of less than 50% (figure 2a). The purpose of our study is to describe the current vaccine acceptance landscape with aims to 1) predict COVID-19 vaccine acceptance using regularly available demographic information, 2) identify the most vulnerable populations, and 3) provide information for public health officials and politicians to develop messaging for all Americans, while targeting communities most in need.
    keywords: acceptance; covid-19; license; participants; preprint; vaccine
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        item: #5372 of 7819
          id: cord-323809-bocidwg4
      author: Patel, Dhwanil
       title: COVID-19 EXTRAPULMONARY ILLNESS - The Impact of COVID-19 on Nephrology Care
        date: 2020-07-25
       words: 3421
      flesch: 40
     summary: All these risk factors are commonly found in patients with CKD and hence in kidney transplant patients. A small preprint study from a Chinese dialysis unit suggested the course may be milder in dialysis patients compared to other patient cohorts [26]
    keywords: acute; aki; covid-19; dialysis; disease; kidney; patients; transplant
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        item: #5373 of 7819
          id: cord-323816-3m1iu9j2
      author: Singh, Awadhesh Kumar
       title: Impact of COVID-19 and comorbidities on health and economics: Focus on developing countries and India
        date: 2020-08-27
       words: 2694
      flesch: 35
     summary: Despite the huge number of COVID-19 patients, India still has low volume research at the moment. A similar finding of disproportionately higher asymptomatic (46.3%) COVID-19 patients were also observed from Kuwait
    keywords: comorbidities; countries; covid-19; diabetes; india; mortality; patients
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        item: #5374 of 7819
          id: cord-323826-nxst9poy
      author: Amir-Behghadami, Mehrdad
       title: Electronic screening through community engagement: A national strategic plan to find COVID-19 patients and reduce clinical intervention delays
        date: 2020-05-04
       words: 740
      flesch: 41
     summary: In addition, this plan is consistent with the overall goal of developing health systems, strengthening their capacity to meet the needs of the community, and achieving universal health coverage. These centers, as community health centers, play an important role in these efforts; they are responsible for delivering integrated care services to the population in geographically defined areas.
    keywords: covid-19; health; screening
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        item: #5375 of 7819
          id: cord-323898-054gv684
      author: Khan, Anas A.
       title: Survival and Estimation of Direct Medical Costs of Hospitalized COVID-19 Patients in the Kingdom of Saudi Arabia (Short Title: COVID-19 Survival and Cost in Saudi Arabia)
        date: 2020-10-13
       words: 3351
      flesch: 51
     summary: Presenting Characteristics, Comorbidities, and Outcomes among 5700 Patients Hospitalized with COVID-19 in the Survival analysis of hospital length of stay of novel coronavirus (COVID-19) pneumonia patients in Sichuan, China Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: A prospective cohort study Predictors of mortality in hospitalized COVID-19 patients: A systematic review and meta-analysis Prevalence and risk factors of mortality among hospitalized patients with COVID-19: This higher risk of mortality among ICU patients aligns with the findings of research studies among hospitalized COVID-19 patients [23] .
    keywords: cost; covid-19; icu; mortality; patients; saudi; survival
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        item: #5376 of 7819
          id: cord-323906-ro078y52
      author: Sardu, Celestino
       title: Implications of AB0 blood group in hypertensive patients with covid-19
        date: 2020-08-14
       words: 3590
      flesch: 37
     summary: In this prospective study, we analyzed covid-19 hypertensive patients consecutively admitted to the Department of Infectious Disease at University of Campania Luigi Vanvitelli, Naples, Italy between February 10, 2020 and April 20, 2020. Such a negative correlation between hypertension and clinical prognosis in covid-19 patients has been deeply investigated in recent trials [1, 2] .
    keywords: blood; blood group; covid-19; data; death; group; infection; injury; patients; study
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        item: #5377 of 7819
          id: cord-323910-lms3xw4k
      author: Putman, Michael
       title: Antirheumatic Disease Therapies for the Treatment of COVID‐19: A Systematic Review and Meta‐analysis
        date: 2020-08-02
       words: 4594
      flesch: 38
     summary: Included studies described one or more relevant clinical outcomes in five or more people who were infected with SARS‐CoV‐2 and were treated with antirheumatic disease therapy between 01/01/2019 and 05/29/2020. Infectious Diseases (except HIV/AIDS) Tocilizumab therapy reduced intensive care unit admissions and/or mortality in COVID-19 patients Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: results from a single Italian Centre study on tocilizumab versus standard of care
    keywords: bias; cohort; covid-19; disease; hydroxychloroquine; mortality; patients; risk; studies; study
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        item: #5378 of 7819
          id: cord-323923-5j8kowzv
      author: Peiffer-Smadja, Nathan
       title: Anticovid, a comprehensive open-access real-time platform of registered clinical studies for COVID-19
        date: 2020-06-08
       words: 1090
      flesch: 45
     summary: key: cord-323923-5j8kowzv authors: Peiffer-Smadja, Nathan; Lescure, François-Xavier; Sallard, Erwan; Ravaud, Philippe; Vegreville, Bruno; Zeitoun, Jean-David title: Anticovid, a comprehensive open-access real-time platform of registered clinical studies for COVID-19 date: 2020-06-08 journal: J Antimicrob Chemother DOI: 10.1093/jac/dkaa223 sha: doc_id: 323923 cord_uid: 5j8kowzv nan The coronavirus disease 2019 (COVID-19) pandemic, caused by the SARS-CoV-2 coronavirus, emerged in Wuhan, China in December 2019 and spread worldwide in early 2020. The platform is updated every day and displays studies in a user-friendly website, providing a live review of registered clinical studies and their main design features in real time.
    keywords: studies
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        item: #5379 of 7819
          id: cord-323934-vew4uxu4
      author: Mohanty, S. K.
       title: Impact of COVID-19 Attributable Deaths on Longevity, Premature Mortality and DALY: Estimates of USA, Italy, Sweden and Germany
        date: 2020-07-07
       words: 3136
      flesch: 53
     summary: Life expectancy, YPLL and DALY were estimated under four scenarios; no COVID-19 deaths, actual number of COVID-19 deaths as of 22nd May, 2020 and anticipating COVID-19 death share of 6% and 10% , respectively. https://doi.org/10.1101/2020.07.06.20147009 doi: medRxiv preprint Inadequate testing and misclassification of deaths by cause underestimate the extent of COVID-19 deaths.
    keywords: covid-19; deaths; license; medrxiv; mortality; preprint
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        item: #5380 of 7819
          id: cord-323940-ubazgvov
      author: Cafiero, Concetta
       title: Pharmacogenomics and Pharmacogenetics: In Silico Prediction of Drug Effects in Treatments for Novel Coronavirus SARS-CoV2 Disease
        date: 2020-10-13
       words: 7372
      flesch: 26
     summary: • PharmGKB website provides a diverse array of PGx information, from annotations of the primary literature to guidelines for adjusting drug treatment based on genetic information. To our knowledge, although a considerable number of ADR episodes in Covid-19 patients have to date been described in the literature, there has been no pharmacogenetic study attempting to correlate the clinical outcomes of drug treatment with gene variants.
    keywords: coronavirus; cov2; covid-19; disease; drug; effects; efficacy; infection; patients; pharmacogenetic; response; sars; studies; study; therapy; toxicity; treatment; use; variants
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        item: #5381 of 7819
          id: cord-323941-6rdveab3
      author: Levine, Diane Thembekile
       title: Child safety, protection, and safeguarding in the time of COVID-19 in Great Britain: Proposing a conceptual framework
        date: 2020-08-13
       words: 6235
      flesch: 35
     summary: BASW website Vulnerable Groups and Latest Data Supporting vulnerable children and young people during the coronavirus (COVID-19) outbreak -actions for educational providers and other partners Attendance in education and early years settings during the coronavirus outbreak: 23 March to 11 Developmental Psychopathology and the Diagnosis of Mental Health Problems Among Youth Let's stop feeding the risk monster: Towards a social model of 'child protection'. In contrast, the aspirational conceptual framework re-frames the flow of information in a way that enables: a) a more holistic and child-led flow of information/data across the micro and macrosystems; b) places child development and their articulation of that development in a crucial, intersectional position in the data flow; c) suggests a single data flow through the interconnected systems intended to act as protective factors for vulnerable/at risk children and young people, and; d) recognises the importance of effective digital mediation of services for those who need it most.
    keywords: children; covid-19; framework; health; pandemic; people; protection; safeguarding; social
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        item: #5382 of 7819
          id: cord-323943-9916y6x0
      author: Platt, Daniel E
       title: Lies, Gosh Darn Lies, and Not Enough Good Statistics: Why Epidemic Model Parameter Estimation Fails
        date: 2020-04-21
       words: 4149
      flesch: 40
     summary: If, as tracking numbers increased, testing surveillance was broad enough to pick up community spread individuals proportional to total numbers of tests applied, then the proportion of positives from the tests may reflect population rates. Since the problem of identifying rate limiting parameters prior to peak is underdetermined, these rates must be determined elsewhere.
    keywords: cases; license; parameters; population; preprint; rate; symptomatic; time
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        item: #5383 of 7819
          id: cord-323965-6mzzibj8
      author: Kapoor, Krishan Mohan
       title: COVID‐19 Pandemic: Consensus Guidelines for Preferred Practices in an Aesthetic Clinic
        date: 2020-05-16
       words: 3358
      flesch: 44
     summary: The general guidelines for aesthetic procedures also included minimum conversations with the patient during the procedure, not allowing the patient attendant to be in the procedure room, and also avoid the helping staff/nurse to be in the procedure room while the procedure is being performed, if possible. In aesthetic clinics, most procedures are provided on one to one basis by the physician or therapist.
    keywords: clinic; consensus; covid-19; guidelines; infection; patient; procedure; risk; staff
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        item: #5384 of 7819
          id: cord-323966-vj9za3cx
      author: Collier, Karole T.
       title: COVID 19: Surgery & the question of race
        date: 2020-05-20
       words: 1380
      flesch: 46
     summary: In this moment, our response to African American COVID disparities is critical and signifies our call to action for all vulnerable populations affected. Looking back to the not so distant past, the AIDS epidemic gave us a clear framework of this relationship and the lasting consequences of novel epidemics to African American health.
    keywords: covid-19; disparities; health; race
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        item: #5385 of 7819
          id: cord-323980-rcyjthze
      author: Willems, Laurent M.
       title: SARS-CoV-2-related rapid reorganization of an epilepsy outpatient clinic from personal appointments to telemedicine services: A German single-center experience
        date: 2020-10-06
       words: 4382
      flesch: 33
     summary: Patients with epilepsy may be a highly vulnerable group for such supply problems, given the driving restrictions applied to patients with ongoing seizures [43] . When the SARS-CoV-2 pandemic reached Europe in 2020, a German governmental order forced clinics to immediately suspend elective care, causing a problem for patients with chronic illnesses such as epilepsy.
    keywords: care; cov-2; covid-19; epilepsy; face; patients; sars; telemedicine
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        item: #5386 of 7819
          id: cord-323981-jo2n51mi
      author: Yu, Wei
       title: ACE2 contributes to the maintenance of mouse epithelial barrier function
        date: 2020-10-21
       words: 2947
      flesch: 46
     summary: ACE2 is highly expressed in the gut, but its role has not been fully understood and thus COVID-19 treatments intending to downregulate ACE2 level may cause untoward side effects. Logically, the implication of ACE2 blockers (ACEIs) would constitute a novel strategy to treat COVID-19.
    keywords: ace2; calcium; covid-19; fig; gut; mice; organoids; patients
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        item: #5387 of 7819
          id: cord-324035-43jy23ic
      author: Fronterre, C.
       title: COVID-19 in England: spatial patterns and regional outbreaks
        date: 2020-05-20
       words: 3541
      flesch: 41
     summary: Other important covariates are the estimated total population size for each LTLA taken from ONS December 2019 predictions, together with a dummy variable encoding weekday vs weekend (to account for obvious weekend dips in case data). . These factors show marked variation at small spatial scales, for example within a single town, and higher resolution case data may allow us to account for these variables to improve our predictions.
    keywords: covid-19; data; england; incidence; license; preprint; region
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        item: #5388 of 7819
          id: cord-324038-1ub2d92w
      author: Calvo, Cristina
       title: Epidemiological update on SARS-CoV-2 infection in Spain. Comments on the management of infection in pediatrics()
        date: 2020-03-26
       words: 1145
      flesch: 50
     summary: Of the 63 patients known to have been tested, 13 (20%) were contacts of confirmed COVID-19 cases, 15 (28%) were patients with compatible symptoms and risk factors (travel to high-risk area or close contact with adults with compatible symptoms and a history of travel to a high-risk area), and 35 (63%) Two of them were contacts of confirmed cases, 2 were first-degree relatives of a contact of a confirmed case, and 1 was a case with no identifiable source of infection.
    keywords: cases; children; covid-19
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        item: #5389 of 7819
          id: cord-324041-lqokztor
      author: Saussez, Sven
       title: Anosmia: an evolution of our understanding of its importance in COVID-19 and what questions remain to be answered
        date: 2020-09-09
       words: 3083
      flesch: 36
     summary: Loss of sense of smell as marker of COVID-19 infection Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Loss of smell and taste in 2013 European patients with mild to moderate COVID-19 Psychophysical olfactory tests and detection of COVID-19 in patients with sudden onset olfactory dysfunction: a prospective study Objective olfactory evaluation of self-reported loss of smell in a case series of 86 COVID-19 patients Neurologic manifestations in hospitalized patients with COVID-19: the ALBACOVID registry Smell dysfunction: a biomarker for COVID-19 Anosmia in COVID-19 patients Olfactory and gustatory function impairment in COVID-19 patients: Italian objective multicenter-study Early recovery following new onset anosmia during the COVID-19 pandemic: an observational cohort study Smell and taste recovery in COVID-19 patients: A 60 day objective and prospective study Elevated ACE2 expression in the olfactory neuroepithelium: implications for anosmia and upper respiratory SARS-COV-2 entry and replication Tumor necrosis factor-alpha convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2) In that way, we observed that severe patients have less ear, nose and throat complaints than mild patients [2, 3] , where the ENT symptoms are prevalent.
    keywords: anosmia; covid-19; infection; loss; olfactory; patients
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        item: #5390 of 7819
          id: cord-324060-vvexfg1c
      author: Bogdanos, Dimitrios P.
       title: When there is a pandemic there is no time to waste: should we have hydroxychloroquine in our armoury against COVID-19 infected patients?
        date: 2020-03-31
       words: 2737
      flesch: 46
     summary: key: cord-324060-vvexfg1c authors: Bogdanos, Dimitrios P.; Daniil, Zoi; Zakynthinos, Epaminondas; Gourgoulianis, Konstantinos; Sakkas, Lazaros I. title: When there is a pandemic there is no time to waste: should we have hydroxychloroquine in our armoury against COVID-19 infected patients? date: 2020-03-31 journal: The safety profile of the drug specifically for COVID-19 treated patients is also a topic of intense research.
    keywords: chloroquine; coronavirus; covid-19; drug; hydroxychloroquine; patients; pneumonia; treatment
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        item: #5391 of 7819
          id: cord-324075-8r7v0g29
      author: Jiang, Yuanyuan
       title: COVID‐19 affected patients' utilization of dental care service
        date: 2020-08-04
       words: 749
      flesch: 42
     summary: The objective of the study was to investigate the influence of COVID-19 on patients' utilization of dental services during the COVID-19 pandemic. It has been found that females were more apprehensive about the risk of an aerosolized spreading of infection during dental procedures (Ashok et al., 2016) and suffered a greater psychological impact and a higher level of stress during dental visits (Wang et al.., 2020) .
    keywords: covid-19; patients
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        item: #5392 of 7819
          id: cord-324092-ertcvh8x
      author: Madani, Azzeddine
       title: The Psychological Impact of Confinement Linked to the Coronavirus Epidemic COVID-19 in Algeria
        date: 2020-05-21
       words: 5177
      flesch: 39
     summary: This questionnaire of 29 items is composed of three subscales: social impact, psychological impact, and impact on mobility. The statistical results also show that the Alpha-Cronbach coefficient, in the 10 questions on psychological impacts, is equal to 0.782, which indicates the reliability of the study tool.
    keywords: confinement; coronavirus; covid-19; epidemic; impact; respondents; study
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        item: #5393 of 7819
          id: cord-324143-ztj6o4ob
      author: Harper, Craig A.
       title: Functional Fear Predicts Public Health Compliance in the COVID-19 Pandemic
        date: 2020-04-27
       words: 5746
      flesch: 34
     summary: In this paper, we explore some of the potential psychological triggers for this inconsistency in social distancing behavior. Specifically in relation to COVID-19, while perceiving the virus to be severe has been linked with worse mental health outcomes (Li et al. 2020) , feeling personally at risk of infection predicted a greater propensity to engage in hand washing and social distancing behaviors in the early stages of the pandemic (Wise et al. 2020) .
    keywords: anxiety; behaviors; covid-19; fear; health; pandemic; public; virus
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        item: #5394 of 7819
          id: cord-324159-jv3lknl8
      author: Ashraf, Muddasir
       title: Acute Stroke in a Young Patient With Coronavirus Disease 2019 in the Presence of Patent Foramen Ovale
        date: 2020-09-03
       words: 1737
      flesch: 45
     summary: We did start the patient on prophylactic enoxaparin sodium, which is the standard of care in stroke patients admitted to the hospital for deep venous thrombosis prophylaxis. Large-vessel stroke as a presenting feature of COVID-19 in the young Incidence of thrombotic complications in critically ill ICU patients with COVID-19 High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in The Factor VIII acute phase response requires the participation of NFkappaB and C/EBP Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases COVID-19-associated hyperviscosity: a link between inflammation and thrombophilia? Hypercoagulability of COVID-19 patients in the intensive care unit: a report of thromboelastography findings and other parameters of Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Exploring possible mechanisms for COVID-19 induced thrombocytopenia: unanswered questions The versatile heparin in COVID-19 Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Lupus anticoagulant and abnormal coagulation tests in patients with Covid-19
    keywords: acute; covid-19; patients; stroke
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        item: #5395 of 7819
          id: cord-324175-5c4ijkpm
      author: Kassas, Mohamed El
       title: COVID-19 in Egypt: Through Crisis to Adaptation; a gastroenterologist’s Perspective
        date: 2020-07-19
       words: 2417
      flesch: 36
     summary: High levels of care for liver disease patients are not provided universally everywhere in Egypt, and sometimes patients have to travel for hundred kilometers to reach tertiary care centers where they are followed up. First, cancer patients are exposed to infection while on their way to cancer centers to receive their medications.
    keywords: covid-19; egypt; hepatitis; infection; liver; pandemic; patients
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        item: #5396 of 7819
          id: cord-324185-zt88o3co
      author: Sovacool, Benjamin K.
       title: Contextualizing the Covid-19 pandemic for a carbon-constrained world: Insights for sustainability transitions, energy justice, and research methodology
        date: 2020-10-31
       words: 7230
      flesch: 35
     summary: The energy crises revealed by COVID: intersections of indigeneity, inequity, and health Emergency measures to protect energy consumers during the Covid-19 pandemic: a global review and critical analysis Just transitions: histories and futures in a post-COVID world Culture and low-carbon energytransitions The cultural barriers to a low-carbon future: a review of six mobility and energy transitions across 28 countries The role of Lucha Libre in the construction of Mexican male identity Validity of energy social research during and after COVID-19: challenges, considerations, and responses Scientific research on the coronavirus is being released in a torrent Coronavirus comes home? It features articles that ask, and answer: What are the known and anticipated impacts of Covid-19 on energy demand and climate change?
    keywords: carbon; change; climate; covid-19; demand; disease; energy; evs; impacts; oil; pandemic; people; research; social; transitions; united; volume
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        item: #5397 of 7819
          id: cord-324186-yw5qpbme
      author: Kovalic, Alexander J.
       title: Prevalence of chronic liver disease in patients with COVID-19 and their clinical outcomes: a systematic review and meta-analysis
        date: 2020-07-28
       words: 2413
      flesch: 45
     summary: The prevalence of CLD patients (73 studies, 24,299 patients) was 3% among all COVID-19 patients. The prevalence of CLD patients was similar in COVID-19 positive and negative population (pooled OR 0.79
    keywords: cld; covid-19; liver; patients; studies
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        item: #5398 of 7819
          id: cord-324198-b8f99z8r
      author: Allam, Zaheer
       title: Underlining the Role of Data Science and Technology in Supporting Supply Chains, Political Stability and Health Networks During Pandemics
        date: 2020-07-24
       words: 6793
      flesch: 39
     summary: All the data collected from these platforms and numerous others that are actively being used elsewhere across the globe would remain its usefulness, even post-COVID-19, but this will require a superior statistical modeling tools to manage the increasing magnitude of such data. This far, in the medical field, with such technologies, there is evidence that it is now possible to perform noninvasive surgeries that reduce fatalities and also reduce healing time for patients, and such have proven beneficial (Elrod, 2014) , especially during this period of COVID-19.
    keywords: cities; coronavirus; countries; covid-19; data; devices; health; people; spread; technologies; use; world
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        item: #5399 of 7819
          id: cord-324204-y8eckkyb
      author: Stevens, Michael P.
       title: Involving antimicrobial stewardship programs in COVID-19 response efforts: All hands on deck
        date: 2020-03-13
       words: 757
      flesch: 29
     summary: key: cord-324204-y8eckkyb authors: Stevens, Michael P.; Patel, Payal K.; Nori, Priya title: Involving antimicrobial stewardship programs in COVID-19 response efforts: All hands on deck date: 2020-03-13 journal: Infection control and hospital epidemiology DOI: 10.1017/ice.2020.69 sha: doc_id: 324204 cord_uid: y8eckkyb nan To the Editor-To our knowledge, no formal recommendations exist for the inclusion of antimicrobial stewardship programs (ASPs) in disaster planning or emergency response preparedness efforts. This yielded 254 responses: 30% noted direct involvement, 28% indicated indirect involvement, and 39% indicated no involvement in emergency response efforts or planning.
    keywords: asps; efforts; response
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        item: #5400 of 7819
          id: cord-324210-zpb9jicw
      author: Russell, Beth
       title: Anosmia and ageusia are emerging as symptoms in patients with COVID-19: What does the current evidence say?
        date: 2020-04-03
       words: 1123
      flesch: 48
     summary: Nevertheless, experts in rhinology have suggested that the onset of such symptoms could either act as a trigger for testing for the disease where possible, or could be a new criterion to self-isolate. Nevertheless, experts in rhinology have suggested that the onset of such symptoms could either act as a trigger for testing for the disease where possible, or could be a new criterion to self-isolate.
    keywords: ageusia; anosmia; symptoms
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        item: #5401 of 7819
          id: cord-324234-3l8n9mhf
      author: Brennan, John
       title: Social work, mental health, older people and COVID-19
        date: 2020-05-12
       words: 2722
      flesch: 47
     summary: Older people with mental health difficulties can present with anxiety and depression, dementia-related behaviors, and problems arising from alcohol misuse; a smaller cohort of older people can present with late-onset psychosis or schizophrenic type conditions. In Ireland, social workers have a key role in the care of older people.
    keywords: care; covid-19; health; people; social; workers
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        item: #5402 of 7819
          id: cord-324236-32sxqeko
      author: Hua, Wenbin
       title: Work Characteristics of Orthopaedic Surgeons During the COVID-19 Pandemic: A Single Center Analysis
        date: 2020-08-13
       words: 1316
      flesch: 44
     summary: The work characteristics of orthopaedic surgeons was evaluated by the workplaces of orthopaedic surgeons, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection rate of orthopaedic surgeons and the number of orthopaedic surgeries performed. The number and types of orthopaedic surgeons during the pandemic period, non-pandemic period, and post-pandemic period was compared and summarized.
    keywords: covid-19; pandemic; surgeons
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        item: #5403 of 7819
          id: cord-324245-cfiekxr4
      author: Giorgi-Pierfranceschi, Matteo
       title: Prevalence of asymptomatic deep vein thrombosis in patients hospitalized with SARS-CoV-2 pneumonia: a cross-sectional study
        date: 2020-08-25
       words: 3775
      flesch: 33
     summary: Prophylaxis in Medical Patients with Enoxaparin Study Group Randomized, placebo-controlled trial of dalteparin for the prevention of venous thromboembolism in acutely ill medical patients Investigators ARTEMIS (2006) Efficacy and safety of fondaparinux for the prevention of venous thromboembolism in older acute medical patients: randomized placebo-controlled trial Venous thromboembolism prophylaxis with unfractionated heparin in the hospitalized medical patient: the case for thrice daily over twice daily dosing Duration of venous thromboembolism risk across a continuum in medically ill hospitalized patients Chemical prophylaxis to prevent venous thromboembolism in morbid obesity: literature review and dosing recommendations Venous thromboembolism prophylaxis in critically ill patients Venous thromboembolism in the ICU: main characteristics, diagnosis and thromboprophylaxis VTE incidence and risk factors in patients with severe sepsis and septic shock A risk assessment model for the identification of hospitalized medical patients at risk for venous thromboembolism: the Padua Prediction Score Scoring systems for estimating risk of venous thromboembolism in hospitalized medical patients Publication WHO REFERENCE NUMBER: WHO/COVID-19/laboratory/2020 Ultrasound for lower extremity deep venous thrombosis: multidisciplinary recommendations from the society of radiologists in ultrasound consensus conference Detection of deep-vein thrombosis by real-time B-mode ultrasonography Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Autopsy findings and venous thromboembolism in patients with COVID-19 Systematic assessment of venous thromboembolism in COVID-19 patients receiving thromboprophylaxis: incidence and role of D-dimer as predictive factors Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): the epidemic and the challenges Compression ultrasonography for diagnostic management of patients with clinically suspected deep vein thrombosis: prospective cohort study Prevent Medical Thromboprophylaxis Study Group, Mortality rates and risk factors for asymptomatic deep vein thrombosis in medical patients Cao Bin (2020) VTE represents a frequent and potentially fatal complication in hospitalized patients.
    keywords: covid-19; dvt; patients; pneumonia; prophylaxis; risk; standard; study; thromboembolism
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        item: #5404 of 7819
          id: cord-324246-liyk6mna
      author: Shakoor, Hira
       title: Be well: A potential role for vitamin B in COVID-19
        date: 2020-08-15
       words: 2244
      flesch: 35
     summary: Given that, it is plausible that symptoms of vitamin B12 deficiency are close to COVID-19 infection such as elevated oxidative stress and lactate dehydrogenase, hyperhomocysteinemia, coagulation cascade activation, vasoconstriction and renal and pulmonary vasculopathy [28, 31] . Evidence has shown that the mortality rate is higher in COVID-19 patients with low vitamin D concentrations.
    keywords: covid-19; editorial; immune; patients; sars; vitamin
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        item: #5405 of 7819
          id: cord-324265-j3v3i8vm
      author: Marietta, Marco
       title: COVID-19, coagulopathy and venous thromboembolism: more questions than answers
        date: 2020-07-11
       words: 5042
      flesch: 32
     summary: The severity of the derangement of coagulation parameters in COVID-19 patients has been associated with a poor prognosis, and the use of low molecular weight heparin (LMWH) at doses registered for prevention of venous thromboembolism (VTE) has been endorsed by the World Health Organization and by Several Scientific societies. This review is particularly focused on four clinical questions: What is the incidence of VTE in COVID-19 patients?
    keywords: coagulopathy; covid-19; disease; infection; lmwh; patients; prophylaxis; pts; sars; sepsis; vte
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        item: #5406 of 7819
          id: cord-324270-8rgkop42
      author: Renaud-Picard, Benjamin
       title: Delayed pulmonary abscess following COVID-19 pneumonia: a case report
        date: 2020-06-18
       words: 1188
      flesch: 37
     summary: key: cord-324270-8rgkop42 authors: Renaud-Picard, Benjamin; Gallais, Floriane; Riou, Marianne; Zouzou, Adel; Porzio, Michele; Kessler, Romain title: Delayed pulmonary abscess following COVID-19 pneumonia: a case report date: 2020-06-18 journal: Respir Med Res DOI: 10.1016/j.resmer.2020.100776 sha: doc_id: 324270 cord_uid: 8rgkop42 nan A 59-year-old woman with Grade 2 obesity and a history of iodinated contrast media allergy, but without any other known comorbidity, was admitted to the Strasbourg University Hospital for severe dyspnea with a four-day history of fatigue, myalgia, and a fever of up to 41°C. Since the beginning of the COVID-19 epidemic was first described in China 2 , bacterial and fungal superinfections after COVID-19 pneumonia have been described on multiple occasions 3, 4 .
    keywords: covid-19; patient; pneumonia; pulmonary
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        item: #5407 of 7819
          id: cord-324273-fl7k8ubi
      author: So, M. K. P.
       title: On Topological Properties of COVID-19: Predicting and Controling Pandemic Risk with Network Statistics
        date: 2020-09-18
       words: 6820
      flesch: 50
     summary: This study proposes a network analysis to assess global pandemic risk by linking 164 countries in pandemic networks, where links between countries were specified by the level of 'co-movement' of newly confirmed COVID-19 cases. Governments and healthcare specialists may not ignore relatively high g it which may indicate the relative severity of COVID-19 pandemic risk in countries, especially if those countries are financial, economic or even travel hubs in the region.
    keywords: countries; covid-19; network; pandemic; q q; risk; time
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        item: #5408 of 7819
          id: cord-324300-6iv6c9nw
      author: Goldstein, Mark R
       title: Reply: Use of statins in patients with COVID-19
        date: 2020-05-16
       words: 524
      flesch: 32
     summary: QJM Effects of rosuvastatin on expression of angiotensin-converting enzyme 2 after vascular balloon injury in rats Tissue specific up regulation of ACE2 in rabbit model of atherosclerosis by atorvastatin: role of epigenetic histone modifications SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa Evaluation of ocular symptoms and tropism in patients confirmed with COVID-19 Endothelial cell infection and endotheliitis in COVID-19 Asymptomatic transmission, the Achilles' heel of current strategies to control Covid-19 Statin therapy in COVID-19 infection for the ALLHAT Collaborative Research Group. Therefore, since statin use is so widespread and the drugs are commonly prescribed at high doses, particularly for patients with many of the comorbidities associated with COVID-19, such as cardiovascular disease, diabetes, obesity, and hypertension, it might have a deleterious effect on some manifestations of the disease, by increasing ACE2 receptor expression.
    keywords: covid-19; statin
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        item: #5409 of 7819
          id: cord-324304-3hih17gk
      author: Qarnain, Syed Shuibul
       title: Review on government action plans to reduce energy consumption in buildings amid COVID-19 pandemic outbreak
        date: 2020-05-06
       words: 2843
      flesch: 43
     summary: The Government of Argentina passed decree 311/2020, classifying domestic electricity sector under the framework of Health and emergency plan, it suspended the disconnections due to non-payment of electricity bills for three consecutive bills. This paper analyses the policies taken by administrative governments to address electricity sector in G20 countries.
    keywords: countries; covid-19; electricity; energy; g20; government; pandemic
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        item: #5410 of 7819
          id: cord-324307-2zbm4iwn
      author: Kam, Kai-qian
       title: A Well Infant With Coronavirus Disease 2019 With High Viral Load
        date: 2020-02-28
       words: 1921
      flesch: 57
     summary: As the infant had no remaining well caregivers, he was brought to KKH for clinical assessment and isolation in light of his close contact with confirmed COVID-19 cases. A nasopharyngeal specimen taken on admission and tested by rRT-PCR confirmed the diagnosis of COVID-19 infection with low cycle threshold (N gene, 15.57; Orf1ab gene, 13.73), suggesting high viral load.
    keywords: admission; coronavirus; covid-19; day; infant; sars
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        item: #5411 of 7819
          id: cord-324316-ulb8d5fe
      author: Bramstedt, Katrina A.
       title: Antibodies as Currency: COVID-19’s Golden Passport
        date: 2020-08-25
       words: 1400
      flesch: 42
     summary: Those with negative antibody test results could use various forms of identity theft to confer themselves a positive test result. Currently, COVID-19 antibody testing requires an in-person visit for blood sampling in the inpatient or outpatient setting.
    keywords: antibodies; antibody; covid-19; passport
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        item: #5412 of 7819
          id: cord-324356-v0bqi5c2
      author: Turner, Tari
       title: The crucible of COVID-19: what the pandemic is teaching us about health research systems
        date: 2020-06-01
       words: 1749
      flesch: 50
     summary: We are being reminded that health research systems are slow and noisy as well as that there is a desire for research to inform decision-making, that researchers are great collaborators, and that the walls we are so quick to erect between health research and health practice are unhelpful facades. For health research systems, this is also true.
    keywords: covid-19; health; publication; research
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        item: #5413 of 7819
          id: cord-324359-88vy3dre
      author: Kamara, Foday Mamoud
       title: How villagers in central Sierra Leone understand infection risks under threat of Covid-19
        date: 2020-06-24
       words: 2951
      flesch: 56
     summary: key: cord-324359-88vy3dre authors: Kamara, Foday Mamoud; Mokuwa, Esther Yei; Richards, Paul title: How villagers in central Sierra Leone understand infection risks under threat of Covid-19 date: 2020-06-24 journal: PLoS One DOI: 10.1371/journal.pone.0235108 sha: doc_id: 324359 cord_uid: 88vy3dre BACKGROUND: Concern has been expressed over how well Africa is prepared to cope with the pandemic of Covid-19. We assessed understanding of infection risks via an experimental game.
    keywords: covid-19; disease; game; infection; players; stones
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        item: #5414 of 7819
          id: cord-324364-9p04oeac
      author: Hasan, Syed Shahzad
       title: Mortality and Disease Severity Among COVID-19 Patients Receiving Renin-Angiotensin System Inhibitors: A Systematic Review and Meta-analysis
        date: 2020-09-12
       words: 8005
      flesch: 33
     summary: We systematically reviewed the published studies to assess the association of RAS inhibitors with mortality as well as disease severity in COVID-19 patients. A systematic literature search was performed to retrieve relevant original studies investigating mortality and severity (severe/critical disease) in COVID-19 patients with and without exposure to RAS inhibitors.
    keywords: analysis; angiotensin; arb; covid-19; inhibitors; mortality; outcomes; patients; risk; studies; use
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        item: #5415 of 7819
          id: cord-324366-x3djkzqn
      author: Hao, Fei
       title: COVID-19 and China’s Hotel Industry: Impacts, a Disaster Management Framework, and Post-Pandemic Agenda
        date: 2020-08-05
       words: 8916
      flesch: 41
     summary: The sudden outbreak of COVID-19 swept through Chinese lunar new year-the most important festival in China, casting a dark shadow over the until then thriving hotel industry. In Hubei, more than 180 Dossen hotels were voluntarily designated as anti-pandemic hotels, which hosted more than 20,000 person-times of medical staff from 68 hospitals.
    keywords: business; china; covid-19; crisis; customers; disaster; disaster management; hospitality; hotel; hotel industry; industry; management; pandemic; phase; recovery; service; strategies; study; tourism
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        item: #5416 of 7819
          id: cord-324368-z1sjukgf
      author: Lyons, Zaza
       title: COVID-19 and the mental well-being of Australian medical students: impact, concerns and coping strategies used
        date: 2020-08-10
       words: 2095
      flesch: 46
     summary: Medical students are vulnerable to poor mental well-being. The study aimed to assess the impact of COVID-19 on medical student mental well-being, assess concerns and determine activities used by students to help with the situation.
    keywords: concerns; covid-19; distress; medical; students
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        item: #5417 of 7819
          id: cord-324385-v8onclcc
      author: Woertz, Eckart
       title: Wither the self-sufficiency illusion? Food security in Arab Gulf States and the impact of COVID-19
        date: 2020-07-08
       words: 2826
      flesch: 47
     summary: Food security in Arab Gulf States and the impact of COVID-19 date: 2020-07-08 journal: Food Secur DOI: 10.1007/s12571-020-01081-4 sha: doc_id: 324385 cord_uid: v8onclcc Past approaches to food security in the countries of the Gulf Cooperation Council (GCC) were informed by concerns about food availability. The Oxford handbook of migration crises How COVID-19 may disrupt food supply chains in developing countries Eliminating drastic food Price spikes -A three pronged approach for reserves Oil for Food.
    keywords: chains; countries; covid-19; food; gulf; saudi; sufficiency; value
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        item: #5418 of 7819
          id: cord-324387-mnucvmr1
      author: Dunn, Michael
       title: ‘Your country needs you’: the ethics of allocating staff to high-risk clinical roles in the management of patients with COVID-19
        date: 2020-05-14
       words: 4754
      flesch: 46
     summary: key: cord-324387-mnucvmr1 authors: Dunn, Michael; Sheehan, Mark; Hordern, Joshua; Turnham, Helen Lynne; Wilkinson, Dominic title: ‘Your country needs you’: the ethics of allocating staff to high-risk clinical roles in the management of patients with COVID-19 date: 2020-05-14 journal: J Med Ethics DOI: 10.1136/medethics-2020-106284 sha: doc_id: 324387 cord_uid: mnucvmr1 As the COVID-19 pandemic impacts on health service delivery, health providers are modifying care pathways and staffing models in ways that require health professionals to be reallocated to work in critical care settings. As the COVID-19 pandemic impacts on health service delivery, health providers are modifying care pathways and staffing models in ways that require health professionals to be reallocated to work in critical care settings.
    keywords: care; health; patients; professionals; risk; roles; staff
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        item: #5419 of 7819
          id: cord-324405-6uanhe2p
      author: Burke, Rachel M.
       title: Enhanced contact investigations for nine early travel-related cases of SARS-CoV-2 in the United States
        date: 2020-09-02
       words: 6625
      flesch: 37
     summary: The results of these investigations suggest that the risk of becoming infected with SARS--CoV-2 is high among close household contacts of confirmed COVID-19 patients, especially significant others. In response to the first cases identified in the United States, close contacts of confirmed COVID-19 cases were investigated to enable early identification and isolation of additional cases and to learn more about risk factors for transmission.
    keywords: case; case patient; contacts; cov-2; covid-19; exposure; household; patient; samples; sars; travel
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        item: #5420 of 7819
          id: cord-324483-zvj1ttay
      author: Ganesh, Radhakrishnan
       title: Management of appendicitis during COVID-19 pandemic; short-term outcomes
        date: 2020-09-02
       words: 2790
      flesch: 36
     summary: In this paper, our objective was to evaluate the change in our practice of managing patients admitted with acute appendicitis, and to investigate short-term outcomes after the onset of pandemic. key: cord-324483-zvj1ttay authors: Ganesh, Radhakrishnan; Lucocq, James; Ekpete, Neville Ogbonnia; Ain, Noor Ul; Lim, Su Kwan; Alwash, Al; Bibi, Saira; Alijani, Afshin title: Management of appendicitis during COVID-19 pandemic; short-term outcomes date: 2020-09-02 journal: Scott Med J DOI: 10.1177/0036933020956316 sha: doc_id: 324483 cord_uid: zvj1ttay BACKGROUND AND AIM: COVID-19 pandemic has predisposed patients undergoing surgery to post-operative infection and resultant complications.
    keywords: appendicitis; covid-19; pandemic; patients
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        item: #5421 of 7819
          id: cord-324488-be0m5gqh
      author: Melaku, Tsegaye
       title: Research and intervention priorities for mental health of people living with chronic disease(s) in the midst of the COVID-19 pandemic in low resource settings: A commentary
        date: 2020-08-07
       words: 992
      flesch: 48
     summary: We ask Authors to confirm as part of the submission process that such consent has been obtained, and the manuscript must include a statement to this effect in a consent section at the end of the manuscript, as follows: Written informed consent was obtained from the patient for publication of this case report and accompanying images. If such consent is made subject to any conditions, the Editor in Chief must be made aware of all such conditions.
    keywords: covid-19; health; research
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        item: #5422 of 7819
          id: cord-324498-kl63hglt
      author: Kwok, Benjamin
       title: Pulmonary Embolism Response Team activation during the COVID-19 pandemic in a New York City Academic Hospital: a retrospective cohort analysis
        date: 2020-09-10
       words: 3258
      flesch: 45
     summary: PE in the COVID era patients occurred later in patient's hospital course than pre-COVID era patients. COVID era patients with PE were younger than prior PE patients with less known PE risk factors including malignancy.
    keywords: activations; covid; covid-19; era; patients; pert
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        item: #5423 of 7819
          id: cord-324507-w32pe2pz
      author: Dubé, Mirette
       title: COVID-19 pandemic preparation: using simulation for systems-based learning to prepare the largest healthcare workforce and system in Canada
        date: 2020-08-18
       words: 5746
      flesch: 30
     summary: In analyzing the nine themes, it is clear that the rapid knowledge translation of best practices, new guidelines, and processes following system simulation events can potentially serve other organizations that may seek to learn from our centralized, coordinated approach to using system integration simulation for pandemic planning and preparedness. One of the emerging findings that differed our project from other COVID-19 system simulations experiences both nationally and globally in using simulation as both a learning and evaluation tool to prepare [3, [6] [7] [8] [9] , was recognizing the critical importance of embedding simulation as a central part of the organizational learning, and the overall pandemic preparedness strategy.
    keywords: covid-19; healthcare; outcomes; pandemic; planning; preparedness; processes; response; simulation; systems; team; training
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        item: #5424 of 7819
          id: cord-324509-5c6fzdjm
      author: Huang, Haijun
       title: The association between markers of liver injury and clinical outcomes in patients with COVID‐19 in Wuhan
        date: 2020-07-22
       words: 2159
      flesch: 43
     summary: On the other hand, dynamic changes in liver functions may indicate a certain relationship between liver injury and mortality. Therefore, we retrospectively analysed the clinical characteristics and dynamic changes in liver function based on different liver function levels at admission and different prognosis, in the purpose of finding out risk factors related to liver injury, and associations between markers of liver injury and clinical outcomes in COVID-19, including mortality and mechanical ventilation.
    keywords: covid-19; function; injury; liver; patients
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        item: #5425 of 7819
          id: cord-324528-517vb02n
      author: Zhang, Mo
       title: Terminator or accelerator? Lessons from the peer-to-peer accommodation hosts in China in responses to COVID-19
        date: 2020-11-11
       words: 7974
      flesch: 41
     summary: It is certain that P2P hosts are facing unprecedented challenges due to Moreover, just like COVID-19 is an unknown enemy to scientists, P2PA hosts are making blind decisions without any guidance since the disruptions caused by the pandemic are unlike anything that has happened in modern economic history. However, the current situation in China may offer P2PA hosts worldwide some insights for resuming their businesses.
    keywords: capabilities; covid-19; diplomats; framework; hosts; market; motivation; p2pa; pandemic; period; speculators; study
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        item: #5426 of 7819
          id: cord-324529-xbrdtxnz
      author: Wang, Ming
       title: Clinical characteristics and risk factors of liver injury in COVID-19: a retrospective cohort study from Wuhan, China
        date: 2020-10-07
       words: 4055
      flesch: 45
     summary: There were significant differences in laboratory findings between COVID-19 patients with or without liver injury, including higher white blood cell, neutrophil and lower lymphocyte count in liver injury patients than those without. Liver injury is a common complication in COVID-19 patients.
    keywords: covid-19; data; disease; injury; liver; liver injury; patients; risk; study
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        item: #5427 of 7819
          id: cord-324553-qd8249w3
      author: Cadegiani, F. A.
       title: An open-label prospective observational study of antiandrogen and non-antiandrogen early pharmacological approaches in females with mild-to-moderate COVID-19. The Pre-AndroCoV Female Trial.
        date: 2020-10-06
       words: 6396
      flesch: 38
     summary: The replication of a highly sensitive case-detection guidance that include the occurrence of absolutely any symptom as being suspected for COVID-19 may find barriers that may preclude from a successful approach, including: 1. Lack of general and medical education regarding the unspecific pattern of COVID-19 clinical presentation; 2. Self-judgement of not being affected by COVID-19; 3. Patients were assessed for COVID-19 clinical course, clinical and viral duration, and disease progression.
    keywords: covid-19; females; funder; license; medrxiv; non; preprint; review
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        item: #5428 of 7819
          id: cord-324557-4u8dja0n
      author: Leblanc, Jean‐François
       title: Risk of Transmission of Severe Acute Respiratory Syndrome Coronavirus‐2 by Transfusion: A Literature Review
        date: 2020-08-15
       words: 3049
      flesch: 41
     summary: For those studies which did not detect RNAaemia, this column shows the entire range of times when blood samples were collected. 4, 8, As correctly pointed out by Huang et al., 4 the presence of SARS-CoV-2 genomic material in the blood of asymptomatic/presymptomatic individuals or COVID-19 patients should be referred to as RNAaemia, as opposed to viremia, which refers to the presence of intact, infectious virions in blood.
    keywords: blood; coronavirus; cov-2; covid-19; patients; samples; sars
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        item: #5429 of 7819
          id: cord-324565-p3jl1vie
      author: Asghar, Muhammad Sohaib
       title: Poor Prognostic Biochemical Markers Predicting Fatalities Caused by COVID-19: A Retrospective Observational Study From a Developing Country
        date: 2020-08-05
       words: 3278
      flesch: 42
     summary: Severe sepsis patients also have associated high lactate dehydrogenase (LDH) levels. COVID-19 patients with elevated levels of PCT were associated with a five-fold greater risk of severe disease progression [15] .
    keywords: covid-19; disease; levels; patients; severity; study
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        item: #5430 of 7819
          id: cord-324615-oqjl3hq2
      author: Orendain, Dan Jezreel A.
       title: Ignored and invisible: internally displaced persons (IDPs) in the face of COVID-19 pandemic
        date: 2020-08-06
       words: 2055
      flesch: 48
     summary: As the world has literally been brought to a standstill due to COVID-19, vulnerable groups like urban IDPs are weakened and more prone to experiencing injustice and inequalities. This financial insecurity, coupled with weak social support systems and infrastructures, may also lead to food insecurity, mental health decline, health issues that threatens their quality of life.
    keywords: covid-19; displacement; health; idps; pandemic; world
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        item: #5431 of 7819
          id: cord-324619-y7gilopu
      author: Alam, S.B.
       title: Severe acute respiratory syndrome coronavirus‐2 may be an underappreciated pathogen of the central nervous system
        date: 2020-07-15
       words: 5255
      flesch: 28
     summary: A retrospective study from China found that COVID-19 patients over 60 years old and with neurologic comorbidities were at a higher risk of developing neurologic impairments such as impaired consciousness and cerebrovascular accidents (18). It is possible that COVID-19 patients that have experienced SARS-CoV-2 infection of the CNS via the neuromuscular junction could experience similar complications and long-term follow-up of these patients should be prioritized.
    keywords: article; brain; cells; cns; coronavirus; cov-2; covid-19; disease; human; infection; patients; sars
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        item: #5432 of 7819
          id: cord-324642-uk4ir8po
      author: Okuhara, Tsuyoshi
       title: Examining persuasive message type to encourage staying at home during the COVID-19 pandemic and social lockdown: A randomized controlled study in Japan
        date: 2020-08-21
       words: 3463
      flesch: 56
     summary: More significant differences between intervention messages were found in the specified warning prefectures compared with all prefectures. Compared with other messages, the message from a physician significantly increased participants’ intention to stay at home in areas with high numbers of people infected (versus a governor, p = .002; an expert, p = .023; a resident, p = .004).
    keywords: covid-19; health; home; message; participants; people
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        item: #5433 of 7819
          id: cord-324644-sz5n7a5z
      author: Rehman, Mahin
       title: Atypical Manifestation of COVID-19-Induced Myocarditis
        date: 2020-06-18
       words: 1914
      flesch: 39
     summary: There was some concern about NSAIDs possibly exacerbating the COVID-19 disease course early on in the pandemic but the World Health Organization (WHO) released a publication addressing this and concluding that there is no evidence of severe adverse effects in COVID-19 patients treated with NSAIDs [8] . Angiography revealed normal coronaries and the patient was found to be coronavirus disease 2019 (COVID-19) positive; he was diagnosed with COVID-19 myocarditis.
    keywords: cov-2; covid-19; pain; patient; sars
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        item: #5434 of 7819
          id: cord-324669-qca0uwxo
      author: Radermecker, Coraline
       title: Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19
        date: 2020-09-14
       words: 4897
      flesch: 34
     summary: Meng et al., 2017; Barnes et al., 2020) , and fibrosis (Chrysanthopoulou et al., 2014; Savchenko et al., 2014) , three features encountered in severe forms of COVID-19 patients (Ackermann et al., 2020; Wang et al., 2020; Guan et al., 2020; Zhou et al., 2020; Connors and Levy, 2020) . Moreover, NET components have been detected in the sera of COVID-19 patients and correlated with disease severity (Zuo et al., 2020; Middleton et al., 2020) .
    keywords: cit; covid-19; et al; formation; lung; mpo; nets; neutrophil; patients; sections; table; traps
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        item: #5435 of 7819
          id: cord-324676-pz4rg6up
      author: Stefanini, Giulio G.
       title: ST-Elevation Myocardial Infarction in Patients With COVID-19: Clinical and Angiographic Outcomes
        date: 2020-04-30
       words: 1091
      flesch: 38
     summary: We aimed to evaluate incidence, clinical presentation, angiographic findings, and clinical outcomes of ST-elevation myocardial infarction (STEMI) in patients with All hospitals with catherization laboratories in Lombardy were contacted to collect cases of patients with confirmed COVID-19 who underwent an urgent coronary angiogram because of STEMI between February 20, 2020 (date of first COVID-19 case in Lombardy) and March 30, 2020. key: cord-324676-pz4rg6up authors: Stefanini, Giulio G.; Montorfano, Matteo; Trabattoni, Daniela; Andreini, Daniele; Ferrante, Giuseppe; Ancona, Marco; Metra, Marco; Curello, Salvatore; Maffeo, Diego; Pero, Gaetano; Cacucci, Michele; Assanelli, Emilio; Bellini, Barbara; Russo, Filippo; Ielasi, Alfonso; Tespili, Maurizio; Danzi, Gian Battista; Vandoni, Pietro; Bollati, Mario; Barbieri, Lucia; Oreglia, Jacopo; Lettieri, Corrado; Cremonesi, Alberto; Carugo, Stefano; Reimers, Bernhard; Condorelli, Gianluigi; Chieffo, Alaide title: ST-Elevation Myocardial Infarction in Patients With COVID-19:
    keywords: clinical; covid-19; patients; stemi
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        item: #5436 of 7819
          id: cord-324707-9ld73wv1
      author: Mitjà, Oriol
       title: Hydroxychloroquine for Early Treatment of Adults with Mild Covid-19: A Randomized-Controlled Trial
        date: 2020-07-16
       words: 4274
      flesch: 47
     summary: While WHO has recommended a measure of viral burden in Covid-19 clinical trials, they have neither set up the optimal time for measurement nor the minimal threshold for significant reduction between arms. The added value of our study is the randomized-controlled design and the use of the agreed minimal outcome set for Covid-19 clinical trials, including RT-PCR to conclusively determine the viral burden.
    keywords: arm; covid-19; days; hcq; hydroxychloroquine; load; patients; study; symptoms; treatment; trial
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        item: #5437 of 7819
          id: cord-324708-2ypm0d52
      author: Kumar, Venkatesan Sampath
       title: Bone sarcoma surgery in times of COVID‐19 pandemic lockdown‐early experience from a tertiary centre in India
        date: 2020-07-13
       words: 1861
      flesch: 48
     summary: Council on foreign relations COVID-19 pandemic: a litmus test of trust in the health system French sarcoma group proposals for management of sarcoma patients during the COVID-19 outbreak Surgical management of bone and soft tissue sarcomas and skeletal metastases during the COVID-19 pandemic Management of cancer surgery cases during the COVID-19 pandemic: considerations COVID-19: potential transmission through aerosols in surgical procedures and blood products Preparing for a COVID-19 pandemic: a review of operating room outbreak response measures in a large tertiary hospital in Singapore Survey of COVID-19 disease among orthopaedic surgeons in Wuhan, People's Republic of China Factors associated with local recurrence in operated osteosarcomas: a retrospective evaluation of 95 cases from a tertiary care center in a resource challenged environment Cancer guidelines during the COVID-19 pandemic Document library Bone sarcoma surgery in times of COVID-19 pandemic lockdown The authors declare that there are no conflict of interests. The present study is an evaluation of bone sarcoma patients operated during the lockdown period and their comparison to the cohort operated in the month immediately before the lockdown.
    keywords: covid-19; group; lockdown; patients; period
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        item: #5438 of 7819
          id: cord-324714-mym5xi23
      author: Staunton, Peter
       title: Regional Trauma Patterns During the COVID-19 Pandemic
        date: 2020-08-13
       words: 2267
      flesch: 49
     summary: Analysis was performed to assess trauma volume, aetiology, and changes in trends. In comparison to the corresponding time-period in 2019, trauma theatre activity reduced by almost one half (45.3%) Conclusion The majority of trauma referred to our Dublin based centre during COVID-19 related population restrictions appears to be home based and trauma volumes have decreased.
    keywords: activity; covid-19; home; orthopaedic; pandemic; trauma
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        item: #5439 of 7819
          id: cord-324722-hcil0kj3
      author: Robbins, Shira L.
       title: Economic impact on pediatric ophthalmologists in the time of COVID-19
        date: 2020-07-27
       words: 3260
      flesch: 48
     summary: key: cord-324722-hcil0kj3 authors: Robbins, Shira L.; Packwood, Eric A.; Siegel, Lance M.; Arnold, Robert; Bartiss, Michael; Buffenn, Angela N.; Campolattaro, Brian; Gappy, Christopher; Gerontis, Corina; Go, Jonathan; Kumar, Kartik; Lederman, Carolyn; Ledoux, Danielle; Lichtenstein, Eric; Packwood, Eric; Paviglianiti, Joseph; Reynolds, Andrew; Siegel, Lance; Stevens, Julia; Teed, Ron; Ticho, Ben; Vredevoogd, Lisa title: Economic impact on pediatric ophthalmologists in the time of COVID-19 date: 2020-07-27 journal: J AAPOS DOI: 10.1016/j.jaapos.2020.06.002 sha: doc_id: 324722 cord_uid: hcil0kj3 Abstract In recent months, the COVID-19 pandemic has threatened the financial viability of pediatric ophthalmology practices. Disproportionate staff reduction by multispecialty groups may result from the AAO recommendation to cease all nonemergent care in contrast to pediatric ophthalmology practices, which may have been more influenced by the AAP's directive to remain available for patients.
    keywords: covid-19; ophthalmology; pediatric; physicians; practices; reduction; respondents; staff
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        item: #5440 of 7819
          id: cord-324725-6xu7q927
      author: Bhagavathula, Akshaya Srikanth
       title: Novel Coronavirus (COVID-19) Knowledge and Perceptions: A Survey of Healthcare Workers
        date: 2020-03-13
       words: 2572
      flesch: 51
     summary: In this regard, HCWs are should practice with careful evaluation of COVID-19 related information and should use scientific and authentic content of information sources. Nevertheless, greater encouragement from the health authorities is needed to assimilate COVID-19 related knowledge among HCWs, including doctors. .
    keywords: covid-19; hcws; license; march; preprint
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        item: #5441 of 7819
          id: cord-324727-bj8oei0v
      author: Zhang, Xiaomei
       title: Management of Digestive Disorders and Procedures Associated With COVID-19
        date: 2020-06-03
       words: 1867
      flesch: 39
     summary: Clinical characteristics of coronavirus disease 2019 in China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Don't overlook digestive symptoms in patients with 2019 novel coronavirus disease (COVID-19) Gastrointestinal symptoms and COVID-19: Case-control study from the United States Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: A descriptive, cross-sectional, multicenter study Digestive symptoms in COVID-19 patients with mild disease severity: Clinical presentation, stool viral RNA testing, and outcomes Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection Manifestations of digestive system in hospitalized patients with novel coronavirus pneumonia in Wuhan, China: A single-center, descriptive study Autopsy report of a dead patient with novel coronavirus pneumonia (COVID-19) Genomic characterisation and epidemiology of 2019 novel coronavirus: Implications for virus origins and receptor binding The digestive system is a potential route of SARS-CoV-2 infection: A bioinformatics analysis based on single-cell transcriptomes Specific ACE2 expression in cholangiocytes may cause liver damage after SARS-CoV-2 infection Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: A single-centered, retrospective, observational study Putative probiotic Lactobacillus spp. Excluding drug-related diarrhea, this symptom was prevalent in 22.2% of COVID-19 patients (9) .
    keywords: cov-2; covid-19; diarrhea; patients; sars; symptoms
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        item: #5442 of 7819
          id: cord-324752-t50bg7pq
      author: Lavery, Michael Joseph
       title: Cutaneous manifestations of COVID-19 in children (and adults): A virus that does not discriminate
        date: 2020-11-01
       words: 2657
      flesch: 43
     summary: In children, the dermatologic features appear to occur before or concomitantly with other COVID-19 manifestations. A preliminary review of an emerging issue Clinical features of patients infected with 2019 novel coronavirus in Wuhan Characterisation of COVID-19 pandemic in paediatric age group: A systematic review and meta-analysis Infectious SARS-CoV-2 in feces of patient with severe COVID-19 Pathogenesis of COVID-19 from the perspective of the damage-response framework COVID-19 -clinical management of children admitted to hospital with suspected COVID-19.
    keywords: children; cov-2; covid-19; eruption; manifestations; sars; syndrome
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        item: #5443 of 7819
          id: cord-324776-upfguze6
      author: Zhang, Peihua
       title: Elevated interleukin-6 and adverse outcomes in COVID-19 patients: a meta-analysis based on adjusted effect estimates
        date: 2020-10-17
       words: 1813
      flesch: 45
     summary: key: cord-324776-upfguze6 authors: Zhang, Peihua; Shi, Li; Xu, Jie; Wang, Yadong; Yang, Haiyan title: Elevated interleukin-6 and adverse outcomes in COVID-19 patients: a meta-analysis based on adjusted effect estimates date: 2020-10-17 journal: Immunogenetics DOI: 10.1007/s00251-020-01179-1 sha: doc_id: 324776 cord_uid: With the developing of the epidemic caused by coronavirus disease 2019 , biomarkers which might predict the adverse outcomes of COVID-19 patients gradually attract researchers' attention.
    keywords: analysis; covid-19; effect; patients
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        item: #5444 of 7819
          id: cord-324794-h08uzro4
      author: Kutlu, Ömer
       title: The explosion in scabies cases during COVID‐19 pandemic
        date: 2020-05-23
       words: 665
      flesch: 50
     summary: In conclusion, understanding the increasing number and impacts of scabies during pandemics will allow for better preparation of countries to fight scabies infestation which is another type of outbreak. key: cord-324794-h08uzro4 authors: Kutlu, Ömer; Aktaş, Habibullah title: The explosion in scabies cases during COVID‐19 pandemic date: 2020-05-23 journal: Dermatol Ther DOI: 10.1111/dth.13662 sha: doc_id: 324794 cord_uid: h08uzro4 nan The COVID-19 pandemic emerged in conjunction with changes in many areas of life that need to reassessed and adjusted.
    keywords: covid-19; pandemic
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        item: #5445 of 7819
          id: cord-324809-16zvqizl
      author: Mehta, Neil
       title: Surveillance and Monitoring of Hepatocellular Carcinoma During the COVID-19 Pandemic
        date: 2020-07-08
       words: 4805
      flesch: 21
     summary: Waitlisted patients who will benefit from urgent LT should be prioritized for surveillance whereas it would be reasonable to extend surveillance interval by a short period in HCC patients with lower risk tumor features and those more than 2 years since their last treatment. HCC patients with Barcelona Clinic Liver Cancer (BCLC) stage 0
    keywords: carcinoma; cirrhosis; covid-19; hcc; hepatocellular; imaging; liver; patients; risk; surveillance; treatment
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        item: #5446 of 7819
          id: cord-324839-6w9kdhod
      author: Huang, Jianping
       title: Global prediction system for COVID-19 pandemic
        date: 2020-08-02
       words: 1951
      flesch: 40
     summary: In this article, we integrated the epidemic prediction model with real global pandemic data and considered the influence of environmental factors (temperature and humidity) as well as the implementation of control measures, to establish our own global prediction system, which is the first of global COVID-19 prediction system. Currently, however, no studies have considered the influence of meteorological factors and interventions on global COVID-19 prediction models.
    keywords: cases; covid-19; data; prediction; system
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        item: #5447 of 7819
          id: cord-324856-hf969tav
      author: Abir, Tanvir
       title: Factors Associated with the Perception of Risk and Knowledge of Contracting the SARS-Cov-2 among Adults in Bangladesh: Analysis of Online Surveys
        date: 2020-07-21
       words: 4147
      flesch: 47
     summary: A similar survey conducted to test the knowledge, attitudes, and perceptions of people in the Hubei province, China, about the COVID-19 outbreak found that higher knowledge, attitude and perception scores among residents was related to the ages and socioeconomic statuses of the respondents [22] . Compared with the early lockdown period, the results indicated that perceived risk scores for contracting COVID-19 in late lockdown period reduced significantly (adjusted coefficients (β) −0.85, 95% CI:−1.31, −0.39).
    keywords: cov-2; covid-19; knowledge; lockdown; quarantine; risk; sars; study
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        item: #5448 of 7819
          id: cord-324857-ll3xmk3i
      author: Jenkins, Louis S.
       title: The evolving role of family physicians during the coronavirus disease 2019 crisis: An appreciative reflection
        date: 2020-06-09
       words: 1587
      flesch: 53
     summary: COVID-19 Updated situation reports Trauma centre's caseload down 67% as driving reduces A disruption framework The contribution of family physicians to district health services: A national position paper for South Africa: key: cord-324857-ll3xmk3i authors: Jenkins, Louis S.; Von Pressentin, Klaus B.; Naidoo, Kartik; Schaefer, Rachel title: The evolving role of family physicians during the coronavirus disease 2019 crisis: An appreciative reflection date: 2020-06-09 journal:
    keywords: community; crisis; family; health; roles
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        item: #5449 of 7819
          id: cord-324859-0yuhb5dl
      author: Mulchandani, Rubina
       title: Deciphering the COVID‐19 cytokine storm: Systematic review and meta‐analysis
        date: 2020-11-02
       words: 6722
      flesch: 39
     summary: Well‐designed and adequately powered prospective studies are needed to amplify the current evidence and provide definitive answers to dilemmas regarding timing and type of anti‐COVID‐19 therapy particularly in severe patients. 58 53% M Not given 13 55 The number of T cells and CD8 + T cells was significantly lower in severe patients than that in the mild cases.
    keywords: analysis; coronavirus; covid-19; cytokine; disease; il-6; inflammatory; levels; meta; patients; studies; study
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        item: #5450 of 7819
          id: cord-324898-bjxpuqhr
      author: Lazzeri, Marta
       title: How Italian respiratory physiotherapists have faced and are facing the coronavirus disease 2019 pandemic
        date: 2020-08-03
       words: 1622
      flesch: 25
     summary: Italian suggestions for pulmonary rehabilitation in COVID-19 patients recovering from acute respiratory failure: results of a Delphi process Middle East respiratory syndrome-coronavirus infection: a case report of serial computed tomographic findings in a young male patient Follow-up chest radiographic findings in patients with MERS-CoV after recovery. Many hospital departments have been converted to admit COVID-19 patients: intensive and respiratory subintensive care beds expaned exponentially; pre-triage to access emergency rooms and separate routes for COVID+ and COVID-patients were established; scheduled activities, both for outpatients and for medical/surgical hospitalization were suspended, except for emergencies.
    keywords: covid-19; failure; patients; physiotherapists; rehabilitation
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        item: #5451 of 7819
          id: cord-324919-ciamusjs
      author: Scialo, Filippo
       title: ACE2: The Major Cell Entry Receptor for SARS-CoV-2
        date: 2020-11-10
       words: 5367
      flesch: 32
     summary: Other potential therapeutic approaches include a SARS-CoV-2 spike protein-based vaccine, a TMPRSS inhibitor to block the priming of the spike protein, and blockage of the surface ACE2 receptor by using anti-ACE2 antibody or peptides [81] . This may shed light on factors that modulate cell surface ACE2 receptor affecting viral cell entry and consequently susceptibility to SARS-CoV-2 infection.
    keywords: ace2; angiotensin; binding; converting; cov-2; covid-19; expression; human; infection; protein; receptor; role; sars
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        item: #5452 of 7819
          id: cord-324983-2fjo664i
      author: Chaturvedi, Santosh K.
       title: Spiritual, Moral and Ethical Dilemmata for Healthcare Professionals During Covid-19 Times
        date: 2020-10-27
       words: 959
      flesch: 39
     summary: The concepts of psychosocial rehabilitation and recovery will adapt the new normal. Covid-19, Humanitarian and health care crisis in third world country Embracing uncertainty during COVID-19 times: psychiatry training, research, and practices in an institute Covid-19, coronavirus and mental health rehabilitation at times of crisis Cancer management in India during Covid 19 Managing mental health challenges faced by healthcare workers during covid-19 pandemic Covid-19 related psychiatric disorders and the new psychosocial rehabilitation Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations This has led to a unique experience among health care professionals, specially doctors and nurses, arising from their predicament.
    keywords: covid-19; health; healthcare
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        item: #5453 of 7819
          id: cord-324993-hs66uf1u
      author: Adwibowo, A.
       title: Flattening the COVID 19 curve in susceptible forest indigenous tribes using SIR model
        date: 2020-05-25
       words: 3255
      flesch: 49
     summary: Using the Susceptible Infectious Recovered (SIR) model, the spread of the COVID 19 under 3 intervention scenarios (low, moderate, high) is simulated and predicted in indigenous tribe populations. The COVID 19 SIR model of indigenous tribe populations living in remote Yasuni rainforest enclaves with simulated 25% (low), 50% (moderate), and 75% (high) interventions (x axis: days, y axis: proportion of total population). .
    keywords: cases; covid; model; population; preprint; sir
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        item: #5454 of 7819
          id: cord-325001-5zd6fydo
      author: Sinkala, M.
       title: The COVID-19 Pandemic in Africa: Predictions using the SIR Model Indicate the Cases are Falling
        date: 2020-06-03
       words: 1966
      flesch: 50
     summary: Our results also reveal that of the 51 countries with reported COVID-19 cases, only nine, including South Africa, Egypt and Ethiopia, are likely to report higher monthly COVID-19 cases in June 2020 than those reported in the previous months. This assertion remains valid even when we consider the number of reported COVID-19 cases as a per cent for each of the country's population size (Figure 4b) . .
    keywords: cases; covid-19; pandemic; preprint
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        item: #5455 of 7819
          id: cord-325014-n7mnhk2v
      author: Gujski, Mariusz
       title: Prevalence of Current and Past SARS-CoV-2 Infections among Police Employees in Poland, June–July 2020
        date: 2020-10-11
       words: 4900
      flesch: 43
     summary: Participants aged ≥60 years had a higher odds of positive IgG index vs. those aged 20–29 years (OR: 3.309). Daily vaping also increased the odds of positive IgG index (OR: 2.058).
    keywords: cov-2; covid-19; employees; igg; igm+iga; index; participants; police; sars; study
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        item: #5456 of 7819
          id: cord-325019-hznnoxw6
      author: Benavides-Cordoba, Vicente
       title: Drug Repositioning for COVID-19
        date: 2020-06-30
       words: 2902
      flesch: 33
     summary: COVID-19) -events as they happen Therapeutic options for the 2019 novel coronavirus (2019-nCoV) Immune responses in COVID-19 and potential vaccines: lessons learned from SARS and MERS epidemic Challenges in early clinical development of adjuvanted vaccines Organs-on-chips at the frontiers of drug discovery Why drugs fail in clinical trials in pulmonary arterial hypertension, and strategies to succeed in the future An analysis of the attrition of drug candidates from four major pharmaceutical companies Drug repurposing: progress, challenges and recommendations Drug Repositioning: Identifying and developing new uses for existing drugs From off-label to repurposed drug in nononcological rare diseases: definition and state of the art in selected EU countries Overcoming the legal and regulatory barriers to drug repurposing Can you teach old drugs new tricks? In this review, we present a selection of drugs, of different classes and with potential activity against COVID-19, whose trials are ongoing; and as proofs of concept, double blind, add-on event-driven, would allow proposing research that generates results in less time and preserving quality criteria for drug development and approval by regulatory agencies.
    keywords: covid-19; drug; hydroxychloroquine; patients; repositioning; repurposing; treatment; trials
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        item: #5457 of 7819
          id: cord-325021-rv5fsitx
      author: Giacobbe, Daniele Roberto
       title: Bloodstream infections in critically ill patients with COVID‐19
        date: 2020-06-14
       words: 2702
      flesch: 35
     summary: Finally, although we apparently observed an improved survival of BSI in comparison with previous large studies conducted in non-COVID-19 ICU patients 7 , it should be reminded that our sample size of BSI patients was limited (n = 31) and that follow-up was very short. In this regard, a possible explanation may be the difficulty of diagnosing BSI in patients receiving anti-inflammatory drugs 21 , which prompted us to collect blood cultures in any case of worsening general conditions in COVID-19 patients, even in the absence of fever and increases in C-reactive protein serum levels.
    keywords: bsi; covid-19; icu; incidence; patients; risk; study
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        item: #5458 of 7819
          id: cord-325026-k514rh8g
      author: Parlapani, Eleni
       title: Intolerance of Uncertainty and Loneliness in Older Adults During the COVID-19 Pandemic
        date: 2020-08-19
       words: 7952
      flesch: 42
     summary: Achieving certainty about the structure of intolerance of uncertainty in a treatment-seeking sample with anxiety and depression Fearing the unknown: A short version of the Intolerance of Uncertainty Scale Into the unknown: A review and synthesis of contemporary models involving uncertainty Experimental manipulation of intolerance of uncertainty: A study of a theoretical model of worry The fear of COVID-19 scale: Development and initial validation Fear of the coronavirus (COVID-19): Predictors in an online study conducted in Considerations relating to social distancing measures in response to COVID-19 -second update Epidemics, quarantine and mental health The emotional path to action: Empathy promotes physical distancing during the COVID-19 pandemic COVID-19 and the consequences of isolating the elderly Loneliness and health in older adults: a mini-review and synthesis Loneliness: The Experience of Emotional and Social Isolation A 6-item scale for overall, emotional, and social loneliness: Confirmatory tests on survey data Older adult loneliness: Myths and realities Anxiety, Depression, Loneliness and Social Network in the Elderly: Longitudinal Associations from The Irish Longitudinal Study on Ageing (TILDA) Similarly, the COVID-19 pandemic affected older people in many different aspects.
    keywords: adults; age; anxiety; care; covid-19; health; item; loneliness; pandemic; people; scale; study; symptoms; uncertainty
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        item: #5459 of 7819
          id: cord-325042-fp6pib7u
      author: Sheng, Lingshuang
       title: Clinical characteristics of moderate and severe cases with COVID-19 in Wuhan, China: a retrospective study
        date: 2020-09-19
       words: 2312
      flesch: 44
     summary: These may be the reasons for the high proportion of severe patients in elderly COVID-19 patients, so more attention should be paid to elderly patients. Therefore, we should keep an eye on COVID-19 patients combined with thrombocytopenia and take measures including blood transfusion or anti-inflammatory therapy if necessary.
    keywords: age; cases; clinical; covid-19; group; patients
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        item: #5460 of 7819
          id: cord-325055-todb1d4x
      author: Rychter, Anna Maria
       title: Should patients with obesity be more afraid of COVID‐19?
        date: 2020-06-24
       words: 3273
      flesch: 39
     summary: Clin Obes Obesity increases mortality and modulates the lung metabolome during pandemic H1N1 influenza virus infection in mice Risk of COVID-19 for patients with obesity COVID 19 and the patient with obesity-the editors speak out Hospitalization rates and characteristics of patients hospitalized with laboratory-confirmed coronavirus disease 2019-COVID-NET, 14 States High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation ICNARC report on COVID-19 in critical care Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City. The Lancet Body weight and mortality in COPD: focus on the obesity paradox Pathophysiology and management of acute respiratory distress syndrome in obese patients The effects of obesity on lung volumes and oxygenation The effects of body mass index on lung volumes Obesity and acute lung injury Effect of body mass index in acute respiratory distress syndrome High positive end-expiratory pressure is associated with improved survival in obese patients with acute respiratory distress syndrome Tracheal trauma after difficult airway management in morbidly obese patients with COVID-19 Obesity-induced adipokine imbalance impairs mouse pulmonary vascular endothelial function and primes the lung for injury Obesity and susceptibility to severe outcomes following respiratory viral infection Obesity and respiratory infections: does excess adiposity weigh down host defense? Association of body mass index with mortality in cardiovascular disease: new insights into the obesity paradox from multiple perspectives Obesity paradox in patients with hypertension and coronary artery disease Obesity phenotypes and their paradoxical association with cardiovascular diseases Are metabolically healthy obese patients also hemorheologically healthy? Metabolically healthy obesity and risk of allcause and cardiovascular disease mortality Does COVID-19 disprove the obesity paradox in ARDS?
    keywords: cov-2; covid-19; disease; lung; obesity; patients; risk; sars; weight
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        item: #5461 of 7819
          id: cord-325077-j77wbcr3
      author: Prado-Gascó, Vicente
       title: Stay at Home and Teach: A Comparative Study of Psychosocial Risks Between Spain and Mexico During the Pandemic
        date: 2020-09-30
       words: 8236
      flesch: 43
     summary: This sector is usually highly affected by psychosocial risks, and this could be aggravated during the current health emergency. Psychosocial risks may cause health problems, lack of motivation, and a decrease of effectiveness at work, which in turn affect the quality of teaching.
    keywords: burnout; covid-19; et al; health; mexico; pandemic; resources; risks; spain; teachers; work
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        item: #5462 of 7819
          id: cord-325109-zi1qm589
      author: Ara, Tasnim
       title: Identifying the Associated Risk Factors of Sleep Disturbance During the COVID-19 Lockdown in Bangladesh: A Web-Based Survey
        date: 2020-09-17
       words: 6023
      flesch: 41
     summary: The mediating role of emotion regulation Associations between sleep disturbance and mental health status: a longitudinal study of Japanese junior high school students Sleep complaints and depression in an aging cohort: a prospective perspective Insomnia in young men and subsequent depression: The Johns Hopkins Precursors Study Sleep disturbance and psychiatric disorders: a longitudinal epidemiological study of young adults Epidemiologic study of sleep disturbances and psychiatric disorders: an opportunity for prevention? Sleep disturbance as transdiagnostic: consideration of neurobiological mechanisms Interacting epidemics? The objective of this study is to identify the risk factors associated with sleep disturbance which has developed as a general impact of COVID-19 and new normal life during the lockdown (a measure to control the spread of COVID-19) in Bangladesh.
    keywords: anxiety; bangladesh; covid-19; disturbance; health; lockdown; respondents; risk; sleep; sleep disturbance; study
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        item: #5463 of 7819
          id: cord-325115-obquz9ve
      author: Naik, B Naveen
       title: Real-Time Smart Patient Monitoring and Assessment Amid COVID-19 Pandemic – an Alternative Approach to Remote Monitoring
        date: 2020-06-13
       words: 381
      flesch: 28
     summary: Utilization of remote technology to manage a deluge of critically ill COVID-19 patients may ease the burden on health care facilities and can stem the exposure of health care providers to COVID-19. It assists the skilled intensivist to monitor, alert and manage patient care without being physically present bedside [5] .
    keywords: care; monitoring
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        item: #5464 of 7819
          id: cord-325128-r53up0ug
      author: Diamantis, Sylvain
       title: SARS-cov-2 related deaths in French long-term care facilities: the “confinement disease” is probably more deleterious than the COVID-19 itself
        date: 2020-05-03
       words: 473
      flesch: 56
     summary: 35 An interactive web-based dashboard to track COVID-19 in real 38 time Clinical management of severe acute respiratory 43 infection (SARI) when COVID-19 disease is suspected: Interim guidance V There are however substantial differences in mortality rates between the 13 different LTCFs.
    keywords: covid-19; ltcfs
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        item: #5465 of 7819
          id: cord-325129-faptufak
      author: Meini, Simone
       title: Understanding the Pathophysiology of COVID-19: Could the Contact System Be the Key?
        date: 2020-08-11
       words: 5517
      flesch: 27
     summary: structures and functions of a large multi-domain protein Old protein with a new story: Coronavirus endoribonuclease is important for evading host antiviral defenses Contact system: a vascular biology modulator with anticoagulant, profibrinolytic, antiadhesive, and proinflammatory attributes Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration Mechanism of enhanced kinin release from high molecular weight kininogen by plasma kallikrein after its exposure to plasmin Bradykinin receptors: agonists, antagonists, expression, signaling, and adaptation to sustained stimulation Angioedema due to bradykinin dysregulation Bradykinin stimulates IL-6 production and cell invasion in colorectal cancer cells Release of cytokines from isolated lung strips by bradykinin Chloroquine inhibits production of TNF-alfa, IL-1beta and IL-6 from lipopolysaccharide-stimulated human monocytes/macrophages by different modes Smoking impairs bradykinin-stimulated t-PA release Cellular distribution of human tissue kallikreins: immunohistochemical localization Kinin B1 receptors as a therapeutic target for inflammation Serum proteome changes in dengue virus-infected patients from a dengue-endemic area of India: towards new molecular targets? Endothelial cell permeability during hantavirus infection involves factor XIIdependent increased activation of the kallikrein-kinin system Bradykinin-induced lung inflammation and bronchoconstriction: role in parainfluenze-3 virusinduced inflammation and airway hyperreactivity Tissue kallikrein regulates alveolar macrophage apoptosis early in influenza virus infection The two fACEs of the tissue renin-angiotensin systems: implication in cardiovascular diseases Classical renin-angiotensin system in kidney physiology Unraveling the pivotal role of bradykinin in ACE inhibitor activity Angiotensin-converting enzyme inhibitor-induced cough: ACCP evidence-based clinical practice guidelines Anosmia: differential diagnosis, evaluation, and management Angiotensin-Converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system: celebrating the 20th anniversary of the discovery of ACE2 Identification of Prolyl carboxypeptidase as an alternative enzyme for processing of renal angiotensin II using mass spectrometry Angiotensin-converting enzyme 2 protects from severe acute lung failure Angiotensin-(1-9) ameliorates pulmonary arterial hypertension via angiotensin type II receptor SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19? IL-6-induced high levels of C-reactive protein (CRP) are typically more related to bacterial rather than to viral infections (11): in COVID-19 patients CRP values are very variable.
    keywords: ace; ace2; activation; angiotensin; coagulation; covid-19; fxii; lung; patients; role; system
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        item: #5466 of 7819
          id: cord-325141-x3txhjkr
      author: Grech, Victor
       title: Vaccine hesitancy among Maltese Healthcare workers toward influenza and novel COVID-19 vaccination
        date: 2020-10-01
       words: 3682
      flesch: 44
     summary: Discussion The increased uptake of influenza vaccine is probably due to increased awareness of respiratory viral illness. The increased uptake of influenza vaccine is probably due to increased awareness of respiratory viral illness.
    keywords: covid-19; healthcare; hesitancy; influenza; uptake; vaccination; vaccine; workers
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        item: #5467 of 7819
          id: cord-325152-ffmo67hm
      author: Siddiqui, Raheel S
       title: Onset of Ketosis-Prone Diabetes in the Setting of COVID-19 Infection
        date: 2020-10-03
       words: 1463
      flesch: 41
     summary: The association between type II diabetes and COVID-19 infections needs additional investigations to ascertain the exact mechanism by which COVID-19 infection triggers the onset of full-blown diabetes mellitus. The mechanism by which COVID-19 infection may trigger the onset of full-blown diabetes mellitus remains unknown.
    keywords: diabetes; mellitus; type
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        item: #5468 of 7819
          id: cord-325161-6ghu34m1
      author: Michot, Jean-Marie
       title: Tocilizumab, an anti-IL6 receptor antibody, to treat Covid-19-related respiratory failure: a case report
        date: 2020-04-02
       words: 1014
      flesch: 36
     summary: Dr Jean-Marie Michot JMM reports sponsored Research at Gustave Roussy Cancer Center with Abbvie, Agios, Amgen, Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome Induction of pro-inflammatory cytokines and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Pathological findings of COVID-19 associated with acute respiratory distress syndrome A new era for the treatment of inflammatory autoimmune diseases by interleukin-6 blockade strategy Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial Current concepts in the diagnosis and management of cytokine release syndrome A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 The pathogenesis of severe acute respiratory syndrome (SARS) related to coronavirus involves a cytokine storm with high serum levels of pro-inflammatory cytokines and chemokines interleukin 6 (IL-6), tumor necrosis factor (TNF-alpha), interferon-gamma, IL-1 and IL-12, and IL-8
    keywords: covid-19; cytokine; patients; tocilizumab
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        item: #5469 of 7819
          id: cord-325173-2jw15w28
      author: Zhang, K.
       title: Causally Associations of Blood Lipids Levels with COVID-19 Risk: Mendelian Randomization Study
        date: 2020-07-07
       words: 3316
      flesch: 50
     summary: Some observational studies have found that the level of blood lipids 196 was related to ABO blood group and Table 2 lists the detailed information about these observational 197 studies [24] [25] [26] Besides, some observational studies have found that the blood lipids level was related 225 to ABO blood group.
    keywords: blood; covid-19; license; medrxiv; preprint
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        item: #5470 of 7819
          id: cord-325186-nq6ay4eo
      author: Sieswerda, Elske
       title: Recommendations for antibacterial therapy in adults with COVID-19 – An evidence based guideline
        date: 2020-10-01
       words: 857
      flesch: 26
     summary: BY THE GUIDELINE AND RECOMMENDATIONS: We assessed evidence on the risk of bacterial infections in hospitalized COVID-19 patients, the associated bacterial pathogens, how to diagnose bacterial infections and how to treat bacterial infections. Although the evidence base on bacterial infections in COVID-19 is currently limited, available evidence supports restrictive antibiotic use from an antibiotic stewardship perspective, especially upon admission.
    keywords: covid-19; infection; patients
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        item: #5471 of 7819
          id: cord-325197-j1uo8qmf
      author: Crimi, Ettore
       title: Epigenetic susceptibility to severe respiratory viral infections: pathogenic and therapeutic implications: a narrative review
        date: 2020-08-20
       words: 6080
      flesch: 21
     summary: The architecture of SARS-CoV-2 transcriptome Control of viral infections by epigenetic-targeted therapy Epigenetic mechanisms of importance for drug treatment Curcumin alleviates macrophage activation and lung inflammation induced by influenza virus infection through inhibiting the NF-kB signaling pathway. key: cord-325197-j1uo8qmf authors: Crimi, Ettore; Benincasa, Giuditta; Figueroa-Marrero, Neisaliz; Galdiero, Massimiliano; Napoli, Claudio title: Epigenetic susceptibility to severe respiratory viral infections: pathogenic and therapeutic implications: a narrative review date: 2020-08-20 journal:
    keywords: coronavirus; cov-2; covid-19; disease; host; human; immune; infections; influenza; mechanisms; patients; response; sars; virus; viruses
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        item: #5472 of 7819
          id: cord-325226-8zrtjuwf
      author: Biswas, Raaj Kishore
       title: Underreporting COVID-19: the curious case of the Indian subcontinent
        date: 2020-09-11
       words: 2600
      flesch: 46
     summary: Similarly, as COVID-19 is not identical with regard to seasonal outbreaks such as measles or dengue in Bangladesh or wild polio in Pakistan, we cannot predict COVID-19 fatality rate from the mortality of the previous seasonal outbreaks, which is likely to lead to a dubious understanding of COVID-19 numbers in these countries. International Labor Organization (2020) COVID-19 and the World of Work Distribution of reported COVID-19 fatalities in three higher income countries (UK, Italy and Germany) and three countries of ISC (Bangladesh, India and Pakistan) for the first 169 days Coronavirus info Bangladesh: Press release Coronavirus: What is the true death toll of the pandemic?
    keywords: bangladesh; countries; covid-19; data; isc; lmics; testing
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        item: #5473 of 7819
          id: cord-325231-hclp7br3
      author: Patel, Zara M
       title: In Reply: Precautions for Endoscopic Transnasal Skull Base Surgery During the COVID-19 Pandemic
        date: 2020-04-23
       words: 753
      flesch: 32
     summary: While we agree there is no hard data at this point proving that endonasal surgery in COVID-19 patients can cause widespread infection of operating room personnel, we feel that until further evidence becomes available the recommended precautions should remain in place: COVID-19 testing should be performed when possible, PPE should be employed for all endoscopic cases and for all involved personnel, surgery should be delayed when possible, consideration should be given to transcranial approaches for certain locations where possible, and PAPR use should be encouraged in the rare occurrence of a symptomatic COVID-19positive patient needing emergent endonasal surgery. The concerns for potential spread during endonasal surgery in a COVID-19 patient remain high, and our recommendations for preoperative COVID-19 testing and use of PPE are strong.
    keywords: covid-19; surgery
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        item: #5474 of 7819
          id: cord-325235-uupiv7wh
      author: Makris, A.
       title: COVID-19 detection from chest X-Ray images using Deep Learning and Convolutional Neural Networks
        date: 2020-05-24
       words: 5445
      flesch: 47
     summary: Deep learning models require a large amount of data in order to perform accurate feature extraction and classification. Transfer learning of class decomposed medical images in convolutional neural networks Deep learning-based detection for covid-19 from chest ct using weak label Covid-resnet: A deep learning framework for screening of covid19 from radiographs Deep convolutional neural networks for image classification: A comprehensive review Gradient-based learning applied to document recognition Deep residual learning for image recognition Utilizing pretrained deep learning models for automated pulmonary tuberculosis detection using chest radiography Imagenet classification with deep convolutional neural networks Very deep convolutional networks for large-scale image recognition Going deeper with convolutions Provable bounds for learning some deep representations Rethinking the inception architecture for computer vision Inception-v4, inception-resnet and the impact of residual connections on learning Inception-v4, inception-resnet and the impact of residual connections on learning Xception:
    keywords: accuracy; classification; covid-19; deep; images; learning; model; networks; preprint
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        item: #5475 of 7819
          id: cord-325241-paztcjm2
      author: Triki, Haitham
       title: Surgical resection for liver cancer during the COVID-19 outbreak
        date: 2020-05-20
       words: 1036
      flesch: 42
     summary: key: cord-325241-paztcjm2 authors: Triki, Haitham; Jeddou, Heithem; Boudjema, Karim title: Surgical resection for liver cancer during the COVID-19 outbreak date: 2020-05-20 journal: Updates Surg DOI: 10.1007/s13304-020-00799-2 sha: doc_id: 325241 cord_uid: paztcjm2 During the 2019 novel coronavirus disease (COVID-19) outbreak, therapeutic strategies must be adapted for liver cancer patients balancing the benefit of surgical resection against the risk of contamination incurred by the patient. The impact of COVID-19 in liver cancer patients who undergo surgery is still unclear due to the scarcity of available data.
    keywords: covid-19; liver; patients
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        item: #5476 of 7819
          id: cord-325274-krmr4d6h
      author: Vulliamy, Paul
       title: Acute aorto‐iliac and mesenteric arterial thromboses as presenting features of COVID‐19
        date: 2020-05-15
       words: 670
      flesch: 35
     summary: In this report we describe two cases of major occlusive arterial events in previously asymptomatic individuals with confirmed COVID-19. In this report, we describe two cases of major occlusive arterial events in previously asymptomatic individuals with confirmed COVID-19.
    keywords: covid-19; infection; sars
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        item: #5477 of 7819
          id: cord-325293-nwxtyrpl
      author: Akhtar, Hubba
       title: COVID-19 (SARS-CoV-2) Infection in Pregnancy: A Systematic Review
        date: 2020-07-30
       words: 3508
      flesch: 55
     summary: COVID-19 infection in pregnancy leads to increased risk in pregnancy complications such as preterm birth, PPROM, and may possibly lead to maternal death in rare cases. One study reported COVID-19 infection in a neonate 36 h after birth [14] .
    keywords: cov-2; covid-19; infection; sars; studies
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        item: #5478 of 7819
          id: cord-325307-agaau27o
      author: Giavedoni, Priscila
       title: Skin Manifestations in COVID-19: Prevalence and Relationship with Disease Severity
        date: 2020-10-12
       words: 4311
      flesch: 34
     summary: Second, we provide an accurate description of the prevalence of skin lesions in COVID-19 patients. Moreover, differentiating chilblain-like lesions from idiopathic and lupus-associated chilblain lesions, and other types of lesions such as generalized maculopapular or urticarial eruptions from drug reactions, is essential, given the frequency and characteristics of the former and the difficulties posed by the latter due to the large number of drugs usually concomitantly received by COVID-19 patients.
    keywords: cases; chilblain; covid-19; disease; hospital; lesions; patients; skin; study
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        item: #5479 of 7819
          id: cord-325309-c9zuh7xs
      author: Stickley, A.
       title: COVID-19 preventive behaviors among people with anxiety and depression: Findings from Japan
        date: 2020-06-20
       words: 2015
      flesch: 44
     summary: In particular, the effects of factors such as socioeconomic disadvantage and lower health literacy, as manifest in a lack of understanding of preventive health behaviors (Kim et al., 2019; Shinn and Viron, 2020) , may be compounded by specific characteristics associated with mental disorders, such as hopelessness, that may hinder adherence to necessary health behaviors (Gehi et al., 2005) . key: cord-325309-c9zuh7xs authors: Stickley, A.; Matsubayashi, T.; Sueki, H.; Ueda, M. title: COVID-19 preventive behaviors among people with anxiety and depression: Findings from Japan date: 2020-06-20 journal: nan DOI: 10.1101/2020.06.19.20135293 sha: doc_id: 325309 cord_uid: c9zuh7xs Little is known about COVID-19 preventive behaviors among individuals with mental health problems.
    keywords: anxiety; behaviors; covid-19; health; preprint
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        item: #5480 of 7819
          id: cord-325313-yj25zkx6
      author: Diao, Bo
       title: Reduction and Functional Exhaustion of T Cells in Patients with Coronavirus Disease 2019 (COVID-19)
        date: 2020-02-20
       words: 3734
      flesch: 46
     summary: Moreover, increasing PD-1 and Tim-3 expression on T cells could be seen as patients progressed from prodromal to overtly symptomatic stages, further indicative of T cell exhaustion. Statistical analysis demonstrated that T cell numbers are negatively correlated to serum IL-6, IL-10 and TNF-α concentration, with patients in decline period showing reduced IL-6, IL-10 and TNF-α concentrations and restored T cell counts.
    keywords: cd4; cells; covid-19; icu; patients; preprint
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        item: #5481 of 7819
          id: cord-325315-m3do6t1j
      author: Rossi, Carlo Maria
       title: A case report of toxic epidermal necrolysis (TEN) in a patient with COVID-19 treated with hydroxychloroquine: are these two partners in crime?
        date: 2020-10-06
       words: 2544
      flesch: 38
     summary: More risk factors result in a higher score and a higher mortality rate (%) as follows: Toxic epidermal necrolysis and Stevens-Johnson syndrome Cytotoxic proteins and therapeutic targets in severe cutaneous adverse reactions The epidemeology and pathogensis of coronavirus (Covid-19) outbreak Clinical features of patients infected with 2019 novel coronavirus in Wuhan COVID-19: combining antiviral and anti-inflammatory treatments SARS CoV-2: recent Reports on antiviral therapies based on lopinavir/ritonavir, darunavir/umifenovir, hydroxychloroquine, remdesivir, favipiravir and other drugs for the treatment of the new coronavirus In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) A trial of lopinavir-ritonavir in adults hospitalized with severe covid-19 Tocilizumab in severe COVID-19 pneumonia and concomitant cytokine release syndrome an algorithm for assessment of drug causality in stevens-johnson syndrome and toxic epidermal necrolysis: comparison with case-control analysis Toxic epidermal necrolysis with prominent facial pustules: a case with reactivation of human herpesvirus 7 Toxic epidermal necrolysis and Stevens-Johnson syndrome are induced by soluble fas ligand Immune pathomechanism and classification of drug hypersensitivity Classification of drug hypersensitivity into allergic, p-i, and pseudo-allergic forms. EudraVigilance Oped Data ADR hydroxychloroquine Drug reaction with eosinophilia and systemic symptoms syndrome to hydroxychloroquine, an old drug in the spotlight Generalized pustular figurate erythema: a newly delineated severe cutaneous drug reaction linked with hydroxychloroquine Cutaneous side-effects of the potential COVID-19 drugs Drug hypersensitivity in HIV infection The interferon-γinduced protein 10/CXCR3 axis is associated with human herpesvirus-6 reactivation and the development of sequelae in drug reaction with eosinophilia and systemic symptoms Reactivation of cytomegalovirus in a patient with Stevens-Johnson syndrometoxic epidermal necrolysis Toxic epidermal necrolysis: Part II.
    keywords: covid-19; drug; epidermal; hydroxychloroquine; necrolysis; patient; skin; syndrome
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        item: #5482 of 7819
          id: cord-325319-4n2g87hx
      author: None
       title: Read, use and cite
        date: 2020-09-29
       words: 1470
      flesch: 66
     summary: I, for one, will look at the use of pre-print servers very differently now, compared with how I perceived them barely 6 months ago. Pre-print servers, which are not peer-reviewed, are dictating policy and may sometimes be the first port of call for those who wish to be updated on current research.
    keywords: covid-19; hip; patients; research
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        item: #5483 of 7819
          id: cord-325324-kh2aal5n
      author: Teng, Shaolei
       title: ACE2 Enhance Viral Infection or Viral Infection Aggravate the Underlying Diseases
        date: 2020-08-06
       words: 4412
      flesch: 40
     summary: -Authors' reply Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Neprilysin inhibitor-angiotensin II receptor blocker combination (sacubitril/valsartan): rationale for adoption in SARS-CoV-2 patients Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics Hypertension, the renin-angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19 Sound Science before Quick Judgement Regarding RAS Blockade in COVID-19 Renin-Angiotensin System Blockers and the COVID-19 Pandemic: At Present There Is No Evidence to Abandon Renin-Angiotensin System Blockers Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. Physiological Effects in the Cardiovascular System Increased angiotensin-(1-7)-forming activity in failing human heart ventricles: evidence for upregulation of the angiotensin-converting enzyme Homologue ACE2 A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury Angiotensin Converting Enzyme 2 and Angiotensin (1-7) axis in Pulmonary Arterial Hypertension Ang II (Angiotensin II) Conversion to Angiotensin-(1-7) in the Circulation Is POP (Prolyloligopeptidase)-Dependent and ACE2 (Angiotensin-Converting Enzyme 2)-Independent Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Structure of SARS coronavirus spike receptorbinding domain complexed with receptor Human coronavirus NL63 employs the severe acute respiratory syndrome coronavirus receptor for cellular entry Understanding Human Coronavirus HCoV-NL63 Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2 Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2 The impact of mutations in SARS-CoV-2 spike on viral infectivity and antigenicity Enhanced receptor binding of SARS-CoV-2 through networks of hydrogen-bonding and hydrophobic interactions Key residues of the receptor binding motif in the spike protein of SARS-CoV-2 that interact with ACE2 and neutralizing antibodies Association of ACE2 genetic polymorphisms with hypertension-related target organ damages in south Xinjiang ACE2 gene polymorphism and essential hypertension: an updated meta-analysis involving 11,051 subjects Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan Covid-19: death rate is 0.66% and increases with age, study estimates Estimates of the severity of coronavirus disease 2019: a model-based analysis Protecting older people from COVID-19: should the United Kingdom start at age 60? Estimating the infection and case fatality ratio for coronavirus disease (COVID-19) using ageadjusted data from the outbreak on the Diamond Princess cruise ship Biomarkers of biological age as predictors of COVID-19 disease severity Human aminopeptidase N is a receptor for human coronavirus 229E Structural and functional analysis of the surface protein of human coronavirus OC43 Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2 Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
    keywords: ace2; angiotensin; coronavirus; cov-2; covid-19; human; patients; protein; sars; spike; viral
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        item: #5484 of 7819
          id: cord-325352-k7aapnx3
      author: Manivel, Vijay
       title: CLUE: COVID‐19 Lung Ultrasound in Emergency Department.
        date: 2020-05-09
       words: 1100
      flesch: 44
     summary: As SARS-CoV-2 infection causes interstitial pneumonitis, there is an extensive use of LUS in COVID-19 patients in China (2) and Italy (3) . In our limited experience with COVID-19 patients, it takes less than 10 minutes to perform LUS, excluding cleaning time.
    keywords: covid-19; lung; lus; ultrasound
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        item: #5485 of 7819
          id: cord-325391-tgli4k5i
      author: Perez, Tamra
       title: Conducting clinical research in the era of Covid-19
        date: 2020-06-10
       words: 1358
      flesch: 49
     summary: The conduct of clinical studies changed soon after the U.S. Department of Health & Human Services (HHS) issued a COVID-19 Public Health Emergency on January 31, 2020. Even now, investigators, industry sponsors, and institutional review boards/ethical committees (IRB/EC) struggle to maintain the safety of trial participants and researchers, while promoting the continuity of ongoing clinical studies.
    keywords: covid-19; protocol; research; sponsors
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        item: #5486 of 7819
          id: cord-325421-1ysn0kyr
      author: Christensen, Johanna
       title: Covid-19 Viremia, Serologies and Clinical Course in a Case Series of Transplant Recipients
        date: 2020-09-03
       words: 2551
      flesch: 48
     summary: The many faces of the anti-COVID immune response Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study Early detection of SARS-CoV-2 antibodies in COVID-19 patients as a serologic marker of infection Validation of a Clinical-Grade Assay to Measure Donor-Derived Cell-Free DNA in Solid Organ Transplant Recipients Clinical features of patients infected with 2019 novel coronavirus in Wuhan A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster COVID-19 Testing: The Threat of False-Negative Results Coronavirus Disease 2019 Pneumonia in Immunosuppressed Renal Transplant Recipients: Patients Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-19 Treatment with convalescent plasma for COVID-19 patients in Wuhan Convalescent plasma: A possible treatment of COVID-19 in India Endothelial cell infection and endotheliitis in COVID-19 Digital droplet PCR for rapid quantification of donor DNA in the circulation of transplant recipients as a potential universal biomarker of graft injury Graft-derived cell-free DNA as an early organ integrity biomarker after transplantation of a marginal HELLP syndrome donor liver Johanna Christensen:
    keywords: covid-19; patients; sars; time; transplant
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        item: #5487 of 7819
          id: cord-325435-b64ijw5o
      author: Reddy, Pavan Kumar
       title: Diabetic ketoacidosis precipitated by COVID-19: A report of two cases and review of literature
        date: 2020-08-01
       words: 1404
      flesch: 52
     summary: Emerging information suggests that individuals with diabetes are at increased risk for complications including death among COVID-19 patients. There are not enough evidences to determine the risk of diabetes for poor outcomes in COVID-19 patients yet, a small study showed that COVID-19 patients with diabetes were not only at higher risk of severe pneumonia but also release excessive inflammatory biomarkers [15] .
    keywords: covid-19; diabetes; dka; patients
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        item: #5488 of 7819
          id: cord-325436-pp3q022y
      author: Alkhatib, Ahmad
       title: Antiviral Functional Foods and Exercise Lifestyle Prevention of Coronavirus
        date: 2020-08-28
       words: 7492
      flesch: 27
     summary: [7] . Increased intake is recommended in high-risk individuals Protein rich foods (e.g., red meat, chicken, seafood) Amino acids and peptides: Anserine, carnosine, taurine, creatine, and 4-hydroxyproline, vitamins, iron, copper Dietary intake of anserine and carnosine promote immunological defence against infections by bacteria, fungi, parasites, and viruses (and coronavirus) through enhanced immune cell functions of monocytes and macrophages Adequate dietary intake, and supplementation of such functional foods, contribute to maintaining optimal levels in the human body, which enhances several aspects of the immune system [7, 45] , and provides an important antiviral prevention of COVID-19
    keywords: acid; activity; cells; covid-19; diabetes; exercise; foods; immune; infections; influenza; intake; lifestyle; prevention; risk; system; virus; vitamin
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        item: #5489 of 7819
          id: cord-325448-rvamjcmx
      author: Bianco, F.
       title: Acute intestinal ischemia in a patient with COVID-19
        date: 2020-06-06
       words: 409
      flesch: 39
     summary: A contrast-enhanced computed tomography scan of the chest and abdomen revealed the classic features of COVID-19 pneumonia as well as air fluid levels in the small bowel with associated mesenteric edema and peritoneal free fluid (Figs. 1, 2a-c) . Tech Coloproctol DOI: 10.1007/s10151-020-02255-0 sha: doc_id: 325448 cord_uid: rvamjcmx nan A 59-year-old man presented to our hospital with a 10-day history of fever, progressive dyspnoea, and a confirmed diagnosis of bilateral COVID-19 interstitial pneumonia.
    keywords: covid-19; surgery
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        item: #5490 of 7819
          id: cord-325449-fl6ob5ja
      author: Wang, Jing
       title: COVID-19 and diabetes: the contributions of hyperglycemia
        date: 2020-10-01
       words: 3433
      flesch: 32
     summary: It is reported that ARDS is the major cause for mortality of COVID-19 patients, which is more prevalent in COVID-19 patients with pre-existing diabetes (Guan et al., 2020) . A great amount of data worldwide reveal that COVID-19 patients with hyperglycemia or T2DM have a greatly enhanced release of inflammatory cytokines or the cytokine storm syndrome, which leads to immunosuppression and multi-organ failure (Ye et al., 2020) , providing further evidence on a potential link between T2DM and COVID-19 due to inflammation and immune deficiency.
    keywords: covid-19; diabetes; et al; infection; patients; sars
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        item: #5491 of 7819
          id: cord-325453-5eskj42c
      author: Haider, Najmul
       title: The Global Health Security index and Joint External Evaluation score for health preparedness are not correlated with countries' COVID-19 detection response time and mortality outcome
        date: 2020-09-07
       words: 5715
      flesch: 51
     summary: Additionally, it appears Iran has exported COVID-19 cases to at least 12 other countries including Bahrain, Kuwait and Lebanon that had not reported importing cases from China or other countries by the end of February 2020 We hypothesised that countries with higher GHSI or JEE scores would have detected their first COVID-19 case earlier, and would experience lower mortality outcome compared to countries with lower scores.
    keywords: cases; china; countries; country; covid-19; ghsi; health; jee; pandemic; risk
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        item: #5492 of 7819
          id: cord-325460-4fhegc0z
      author: Jacobs, Werner
       title: Fatal lymphocytic cardiac damage in coronavirus disease 2019 (COVID‐19): autopsy reveals a ferroptosis signature
        date: 2020-09-22
       words: 3993
      flesch: 34
     summary: In view of the marked inflammation seen in COVID-19 patients and the apparently very poor prognosis of cardiac failure in young patients, myocarditis rather than ischaemic cardiogenic shock has been proposed as the underlying mechanism in some cases of COVID-19 related cardiac injury; nevertheless, there is little published data about the underlying pathologic mechanisms that might cause this type of cardiac failure to occur in COVID-19 patients. We also report on multiple peripheral pulmonary arterial microemboli in both lungs ( Figure 3 , insert), which might reflect the procoagulant profile as well as microangiopathy seen in COVID-19 patients making them prone to thromboembolic complications in large as well as small alveolar capillary vessels.
    keywords: covid-19; death; e06; ferroptosis; lymphocytes; myocarditis; patient; renal; sars; tissue
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        item: #5493 of 7819
          id: cord-325476-38lg4a1u
      author: Rossman, Hagai
       title: A framework for identifying regional outbreak and spread of COVID-19 from one-minute population-wide surveys
        date: 2020-04-09
       words: 2641
      flesch: 43
     summary: We observe that regions with relatively high response rate are regions Prevalence of symptoms for survey responses from neighborhoods in which confirmed cases were present (red) or no confirmed cases were present (blue), presented as estimates and 95% confidence intervals of patients with COVID-19 from a published meta-analysis 8 (x axis) plotted against prevalence from survey data and bootstrap estimates of 95% confidence intervals (y axis); dashed diagonal line, y = x. associated with higher socioeconomic status. For each participant, the symptoms ratio was calculated as the number of reported symptoms divided by the number of symptoms in our predefined list (number of reported symptoms / 6, for participants 18 years of age or less; number of reported symptoms / 5, for participants over 18 years of age).
    keywords: covid-19; data; participants; people; survey; symptoms
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        item: #5494 of 7819
          id: cord-325512-eehp4uh9
      author: Li, Yiwei
       title: Coronavirus disease 2019 (COVID-19) related cytopenia: A protocol for systematic review and meta-analysis
        date: 2020-09-04
       words: 2070
      flesch: 40
     summary: In addition, gray literatures will also be searched, including conference proceedings and reference lists of included studies. Recent papers pointed out the cytopenia in COVID-19 patients including lymphopenia, neutrophilia, thrombocytopenia and lower level of hemoglobin had prognostic significance.
    keywords: analysis; covid-19; meta; patients; studies; study
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        item: #5495 of 7819
          id: cord-325531-riftp8g6
      author: Bhatta, Sabita
       title: New-Onset Seizure as the Only Presentation in a Child With COVID-19
        date: 2020-06-25
       words: 1634
      flesch: 45
     summary: Although we could not trace the potential source of COVID-19 infection in the patient's family, we can assume that the patient contracted the disease owing to a recent surge in COVID-19 cases in his residential area across New York City, USA. Seizure. 2020 Lung ultrasound in children with COVID-19: preliminary findings Neurologic manifestations in an infant with COVID-19 Burden and risk factors for coronavirus infections in infants in rural Nepal Clinical and CT features in pediatric patients with COVID-19 infection: different points from adults
    keywords: children; coronavirus; covid-19; patient; seizure
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        item: #5496 of 7819
          id: cord-325534-psv7v78z
      author: Sangalli, Davide
       title: A single-centre experience of intravenous thrombolysis for stroke in COVID-19 patients
        date: 2020-07-12
       words: 1369
      flesch: 40
     summary: Ongoing collaborative efforts are collecting more data from various centres that hopefully will help clinicians to better delineate the risk/benefit profile of reperfusion strategies in patients with stroke and COVID-19 infection; pending these results, clinicians should be aware of the non-negligible risk inherent to rt-PA treatment delivered to COVID-19 stroke patients. In Italy, some hospitals have been promptly switched into COVID-19 centres and stroke patients diverted to other designated stroke units.
    keywords: acute; covid-19; patients; stroke
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        item: #5497 of 7819
          id: cord-325553-ilx9j89c
      author: Bakhoum, M. F.
       title: Subclinical ocular inflammation in persons recovered from ambulatory COVID-19
        date: 2020-09-23
       words: 1132
      flesch: 41
     summary: A larger study is needed to determine the true prevalence of vitreous cells in persons recovering from COVID-19, and a longitudinal study is needed to determine its long-term ocular health sequelae. . One participant had symptoms consistent with COVID-19 and a simultaneous household contact with confirmed COVID-19.
    keywords: cells; covid-19; persons
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        item: #5498 of 7819
          id: cord-325558-xpr54hvo
      author: Cral, Wilson Gustavo
       title: COVID-19 and oral radiology
        date: 2020-06-18
       words: 643
      flesch: 33
     summary: In dentistry, more specifically in the oral radiology field, certain procedures must be strictly followed when performing radiographic techniques to reduce the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. In light of the risk of intraoral radiographic techniques causing cough stimuli, saliva secretion, and vomiting reflex in some patients, 3 extrabuccal radiographic techniques, such as panoramic radiography and cone-beam computed tomography, are preferable when possible during the COVID-19 pandemic.
    keywords: coronavirus; covid-19; patients
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        item: #5499 of 7819
          id: cord-325559-di8lljoi
      author: Cappello, Francesco
       title: Does SARS-CoV-2 Trigger Stress-Induced Autoimmunity by Molecular Mimicry? A Hypothesis
        date: 2020-06-29
       words: 5212
      flesch: 36
     summary: By resorting to previously known information on genome sequences and protein structures and functions as well, bioinformaticians have been successfully assisting virologists by structurally characterizing proteins of the novel virus, determining the evolutionary trajectories, identifying interactions with host proteins, and providing other important biological insights. Alphavirus Sequence alignment of structural polyproteins belonging to arthritogenic alphaviruses revealed conserved regions which share homology with human proteins implicated in rheumatoid arthritis.
    keywords: cells; coronavirus; cov-2; covid-19; disease; human; immune; mimicry; patients; proteins; sars; virus
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        item: #5500 of 7819
          id: cord-325565-cz9f65ca
      author: Heederik, Dick J.J.
       title: Go slow to go fast: A plea for sustained scientific rigor in air pollution research during the COVID-19 pandemic
        date: 2020-06-25
       words: 2063
      flesch: 36
     summary: Thus, there seems little reason to abandon the rigorous peer review process and expedite manuscript publication for COVID-19 air pollution studies. This far exceeds the granularity of the data used in air pollution studies and most infectious disease outbreak studies.
    keywords: air; covid-19; pollution; studies; study
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        item: #5501 of 7819
          id: cord-325593-ww2vq3n4
      author: Hendren, Nicholas S.
       title: Unique Patterns of Cardiovascular Involvement in COVID-19
        date: 2020-05-14
       words: 1300
      flesch: 25
     summary: ACovCS with cardiac predominate disease may be more apparent at hospital presentation relative to mixed cardiopulmonary disease because the predominate cardiac manifestations (e.g. chest pain due to a myocardial infarction) often results in symptoms which lead patients to seek emergent care. Furthermore, in the minority of patients with COVID-19 who develop shock, patients with cardiac predominate disease would be anticipated to develop cardiogenic rather than distributive shock.
    keywords: cardiac; covid-19; disease; patients
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        item: #5502 of 7819
          id: cord-325599-2gutb4m1
      author: Lapidus, Nathanael
       title: Biased and unbiased estimation of the average length of stay in intensive care units in the Covid-19 pandemic
        date: 2020-10-16
       words: 4401
      flesch: 45
     summary: For example, one may think about the impact of disease knowledge on triage decisions and on the decision to withdraw early mechanical ventilation based on refinement of prognostic factors (ethical issues), bed availability and pressure of this threatening epidemic on the organization of the healthcare system likely modifies the characteristics of admitted patients as well as various specific characteristics of the units (including cultural behaviors), accumulating experience with COVID-19 patients likely improves management procedures according to time. Third and to conclude, whenever the estimates reported in this study would be generalizable to other settings, then this is bad news: long ICU LOS as reported here imply that occupied beds remain unavailable for a long time and this adds additional pressure to the surge in ICU beds encountered in many places worldwide.
    keywords: covid-19; date; days; estimates; icu; los; patients; study
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        item: #5503 of 7819
          id: cord-325619-qmszgw66
      author: Ferrari, Andrea
       title: Children with cancer in the time of COVID‐19: An 8‐week report from the six pediatric onco‐hematology centers in Lombardia, Italy
        date: 2020-05-26
       words: 978
      flesch: 34
     summary: :e28327 Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Prevalence and characteristics of acute respiratory virus infections in pediatric cancer patients Flash survey on SARS-CoV-2 infections in pediatric patients on anti-cancer treatment Risk of COVID-19 for patients with cancer How young patients with cancer perceive the COVID-19 (coronavirus) epidemic in Milan, Italy: is there room for other fears? Although preliminary, our findings suggest that anticancer treatments for pediatric patients can continue with no major adjustments.
    keywords: cancer; cases; covid-19; patients
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        item: #5504 of 7819
          id: cord-325628-pa3dkz2f
      author: Wang, Jinsong
       title: Strategy for treating vascular emergencies during the COVID-19 pandemic in China
        date: 2020-06-01
       words: 1200
      flesch: 40
     summary: Clinicians treating COVID-19 patients face considerable danger of occupational exposure due to the highly infectious nature of the virus and precautions must be taken to prevent medical staff infections. Patients who have unstable vital signs and cannot be screened should be treated as if they 20 were confirmed COVID-19 patients.
    keywords: covid-19; patients; treatment; vascular
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        item: #5505 of 7819
          id: cord-325631-c7jwizpj
      author: Masetti, Chiara
       title: High mortality in COVID‐19 patients with mild respiratory disease
        date: 2020-06-29
       words: 2541
      flesch: 38
     summary: Clinical evaluation of COVID-19 patients depends on the severity of the disease, and since no proven therapy has been so far approved, hospitalization is warranted for observation and supportive care. In our analysis, our aim was to identify risk factors for a predictor model in COVID-19 patients accessing to ER with mild symptoms.
    keywords: analysis; clinical; coronavirus; covid-19; disease; mortality; patients
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        item: #5506 of 7819
          id: cord-325645-rvj4b26t
      author: Dumas, Tara M.
       title: What Does Adolescent Substance Use Look Like During the COVID-19 Pandemic? Examining Changes in Frequency, Social Contexts, and Pandemic-Related Predictors
        date: 2020-07-18
       words: 5088
      flesch: 45
     summary: Further, adolescents concerned with maintaining their peer reputation may be especially likely to maintain social substance use during the COVID-19 crisis. Thus, more popular adolescents who are especially concerned with how COVID-19-related social distancing will affect their reputation may be at heightened risk for social substance use.
    keywords: adolescents; covid-19; face; social; substance; use
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        item: #5507 of 7819
          id: cord-325649-zzhsrytw
      author: Rispoli, Rossella
       title: Spine surgery in Italy in the COVID-19 era: Proposal for assessing and responding to the regional state of emergency
        date: 2020-08-07
       words: 2783
      flesch: 44
     summary: The alert level data points relative to the FVG Region of northeast Italy are shown in white points in The proposal for prioritizing surgical activities in relation to health care system alert levels is given in All these patients were admitted urgently due to the onset with neurological deficits and, in one case, for early signs of infection. By the time of the World Health Organization (WHO) classification of the novel coronavirus as a global pandemic (1) , many hospitals in northern Italy were already overcrowded by COVID-19 patients, especially intensive care units, where about 50% of all available ICU beds were occupied by COVID-19 patients ( 2 ) .
    keywords: care; covid-19; health; patients; spine; surgery; system
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        item: #5508 of 7819
          id: cord-325669-6kjlcakt
      author: Fogacci, Silvia
       title: Management of pregnancy-related hypertensive disorders in patients infected with SARS CoV-2: pharmacological and clinical issues
        date: 2020-09-10
       words: 3376
      flesch: 31
     summary: In clinical practice, methyldopa is often prescribed to women affected by systemic lupus erythematosus treated with hydroxychloroquine to prevent flares [32] ., The coadministration of methyldopa and hydroxychloroquine is considered to be safe in hypertensive pregnant women infected with SARS-CoV-2. There are no no contraindications to combined treatment in hypertensive pregnant women infected with SARS-CoV-2 [50] .
    keywords: cov-2; covid-19; evidence; hypertension; infection; pregnancy; sars; women
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        item: #5509 of 7819
          id: cord-325726-65xxevp3
      author: Patel, Piyush
       title: Role of Additive Manufacturing in Medical Application COVID-19 Scenario: INDIA Case study
        date: 2020-11-12
       words: 5036
      flesch: 43
     summary: Boson Machines, a Mumbai-based 3D printing firm IIT-Madras startups develop PPEs from 3D Printers and regular stationery materials Hyderabad start-up is 3D printing face shields, hands-free door openers to stave off COVID's spread China pushes all-out production of face masks in virus fight IIT Kanpur to produce 25,000 masks per day Available at Govt Panels Flag Issues with AgVa Ventilators Bought by PMCARES Fund 3D Printed Multipurpose Door Opener Tool for Covid 19. 3D printing
    keywords: clinical; coronavirus; covid-19; equipment; face; fig; india; manufacturing; masks; pandemic; parts; patients; printing; shields; supply
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        item: #5510 of 7819
          id: cord-325729-2c7btqpl
      author: Larrouquere, Louis
       title: Genesis of an emergency public drug information website by the French Society of Pharmacology and Therapeutics during the COVID‐19 pandemic
        date: 2020-05-11
       words: 2300
      flesch: 49
     summary: While the mass media must take responsibility for providing correct information and facilitating comprehension by citizens, the role of the SFPT as a scholarly society was to contribute to the national effort to provide reliable drug information. The WHO provided general guidelines as to the characteristics and contents that medicines regulatory authority websites should have in order to offer high quality drug information to consumers [12] .
    keywords: article; copyright; covid-19; fig; health; information
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        item: #5511 of 7819
          id: cord-325755-n7vjjw9r
      author: Rai, Deependra Kumar
       title: Post covid 19 pulmonary fibrosis- Is it real threat?
        date: 2020-11-10
       words: 2527
      flesch: 41
     summary: As we move forward through this pandemic, the challenging part is how to manage this COVID-19 Sequelae which may vary from mild in terms of fatigue and body aches to lung fibrosis. Elderly patient who require ICU care and mechanical ventilation are highest risk to develop lung fibrosis.
    keywords: covid-19; disease; fibrosis; lung; patients; post
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        item: #5512 of 7819
          id: cord-325778-y5miy24f
      author: Quigley, Ashley L.
       title: Estimating the Burden of COVID-19 on the Australian Healthcare Workers and Health System
        date: 2020-10-29
       words: 2960
      flesch: 47
     summary: There is no publicly available national data on healthcare worker infections in Australia. The rate of healthcare worker infection was 72/100,000 and of community infection 34/100,000.
    keywords: covid-19; hcw; health; healthcare; infections; outbreaks; workers
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        item: #5513 of 7819
          id: cord-325784-zs1qmfjy
      author: Sher, Leo
       title: Are COVID-19 survivors at increased risk for suicide?
        date: 2020-05-04
       words: 565
      flesch: 36
     summary: Psychological factors that may increase suicide risk among COVID-19 patients include learning about their diagnosis, anxiety, and distress related to symptoms of the disease and stress related to hospitalisation and hospital treatment. Millions of people got sick with In this letter to the editor, I suggest that the COVID-19 survivors especially individuals who had severe COVID-19 are at increased suicide risk.
    keywords: covid-19; suicide
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        item: #5514 of 7819
          id: cord-325788-63jkyx6g
      author: Haddad, Chadia
       title: Association between eating behavior and quarantine/confinement stressors during the coronavirus disease 2019 outbreak
        date: 2020-09-01
       words: 5170
      flesch: 46
     summary: Eating behaviors were not assessed, nor the data and information about eating behaviors, such as the number of meals/ snacks per day, calories consumed, and stances of unplanned eating. When looking at the association between quarantine/ confinement stressors and eating behaviors among the dietitian clients group and the general population group, the results revealed that higher fear of COVID-19 score and higher boredom were associated with higher disturbed eating behavior in the dietitian clients group.
    keywords: anxiety; confinement; covid-19; eating; fear; participants; quarantine; shape; weight
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        item: #5515 of 7819
          id: cord-325793-5vrr7msw
      author: Lahiry, Anup K.
       title: Dermatosurgery Practice and Implications of COVID-19 Pandemic: Recommendations by IADVL SIG Dermatosurgery (IADVL Academy)
        date: 2020-05-10
       words: 1927
      flesch: 56
     summary: If possible, room for suspected COVID-19 patients should be different from those for other emergent surgical patients. If possible, preoperative assessment of surgical patients should ideally include COVID-19 testing.
    keywords: care; covid-19; need; patient; staff; use
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        item: #5516 of 7819
          id: cord-325794-lir8ht2i
      author: Kinar, Y.
       title: Predicting individual risk for COVID19 complications using EMR data
        date: 2020-06-05
       words: 3224
      flesch: 49
     summary: The other was directly derived from initial COVID-19 complications data. The other was directly derived from initial COVID-19 complications data.
    keywords: complications; covid-19; data; medrxiv; model; preprint
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        item: #5517 of 7819
          id: cord-325799-v1egyqt4
      author: Sher, Leo
       title: The impact of the COVID-19 pandemic on suicide rates
        date: 2020-06-15
       words: 3003
      flesch: 45
     summary: Multiple cases of COVID-19 related suicides in the U.S., U.K., Italy, Germany, Bangladesh, India, and other countries have been reported in mass media and psychiatric literature. It is to be hoped that the efforts of clinicians, researchers, and policy makers will reduce COVID-19 related suicides.
    keywords: anxiety; coronavirus; covid-19; disorders; health; pandemic; suicide
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        item: #5518 of 7819
          id: cord-325833-gn4ftbzo
      author: Lepre, Luca
       title: Acute care surgery and post‐operative COVID‐19 pneumonia: a surgical and environmental challenge
        date: 2020-05-04
       words: 815
      flesch: 43
     summary: We suggest active surveillance with a liberal use of RT-PCR test and thoracic CT scan in this setting, to rule out COVID-19 infection, in the effort to offer prompt treatment to infected patients and to protect other patients and health workers. Starting from post-operative day (POD) 3, temperature >38 was detected without any other symptom.
    keywords: covid-19; patients
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        item: #5519 of 7819
          id: cord-325844-w0zqxwdh
      author: Kanekar, Amar
       title: COVID-19 and Mental Well-Being: Guidance on the Application of Behavioral and Positive Well-Being Strategies
        date: 2020-09-12
       words: 2921
      flesch: 40
     summary: Positive mental health and positive psychology have an imminent role to play during this unprecedented public health crisis. There are several determinants of positive mental health such as hardiness, sense of coherence, social support, optimism, and self-esteem [36] that are important in the context of COVID-19.
    keywords: anxiety; covid-19; health; pandemic; stress; support
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        item: #5520 of 7819
          id: cord-325862-rohhvq4h
      author: Zhang, Yong
       title: Applicability of time fractional derivative models for simulating the dynamics and mitigation scenarios of COVID-19
        date: 2020-06-04
       words: 5904
      flesch: 41
     summary: Other complex SEIR models were also applied to model COVID-19 spread, such as the one proposed by Tang et al. key: cord-325862-rohhvq4h authors: Zhang, Yong; Yu, Xiangnan; Sun, HongGuang; Tick, Geoffrey R.; Wei, Wei; Jin, Bin title: Applicability of time fractional derivative models for simulating the dynamics and mitigation scenarios of COVID-19 date: 2020-06-04 journal: Chaos Solitons Fractals DOI: 10.1016/j.chaos.2020.109959 sha: doc_id: 325862 cord_uid: rohhvq4h Fractional calculus provides a promising tool for modeling fractional dynamics in computational biology, and this study tests the applicability of fractional-derivative equations (FDEs) for modeling the dynamics and mitigation scenarios of the novel coronavirus for the first time.
    keywords: china; coronavirus; covid-19; fractional; model; number; people; rate; spread; time
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        item: #5521 of 7819
          id: cord-325869-3mvjc805
      author: Silvestris, Nicola
       title: A moonshot approach toward the management of cancer patients in the COVID-19 time: what have we learned and what could the Italian network of cancer centers (Alliance Against Cancer, ACC) do after the pandemic wave?
        date: 2020-06-11
       words: 2466
      flesch: 37
     summary: The systematic collection of well-annotated biological samples from COVID-19 infected cancer patients is an essential part of our proposal. key: cord-325869-3mvjc805 authors: Silvestris, Nicola; Apolone, Giovanni; Botti, Gerardo; Ciliberto, Gennaro; Costantini, Massimo; De Paoli, Paolo; Franceschi, Silvia; Opocher, Giuseppe; Paradiso, Angelo; Pronzato, Paolo; Sgambato, Alessandro; De Maria, Ruggero title: A moonshot approach toward the management of cancer patients in the COVID-19 time: what have we learned and what could the Italian network of cancer centers (Alliance Against Cancer, ACC) do after the pandemic wave? date: 2020-06-11 journal:
    keywords: cancer; covid-19; data; infection; italy; patients; research
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        item: #5522 of 7819
          id: cord-325896-vbwo2djw
      author: Dirlikov, Emilio
       title: CDC Deployments to State, Tribal, Local, and Territorial Health Departments for COVID-19 Emergency Public Health Response — United States, January 21–July 25, 2020
        date: 2020-10-02
       words: 2909
      flesch: 26
     summary: CDC deployment data were analyzed to summarize activities by deployed CDC teams in assisting state, tribal, local, and territorial health departments to identify and implement measures to contain SARS-CoV-2 transmission (1). CDC deployment data were analyzed to summarize activities by deployed CDC teams in assisting state, tribal, local, and territorial health departments to identify and implement measures to contain SARS-CoV-2 transmission (1) .
    keywords: cdc; covid-19; departments; health; health departments; response; staff; state; teams
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        item: #5523 of 7819
          id: cord-325901-gucnce1f
      author: Juanjuan, Li
       title: Patient reported outcomes of breast cancer patients during the COVID-19 outbreak in the epicenter of China: A cross sectional survey study
        date: 2020-06-07
       words: 3022
      flesch: 45
     summary: key: cord-325901-gucnce1f authors: Juanjuan, Li; Santa-Maria, Cesar Augusto; Hongfang, Feng; Lingcheng, Wang; Pengcheng, Zhang; Yuangbing, Xu; Yuyan, Tan; Zhongchun, Liu; Bo, Du; Meng, Lan; Qingfeng, Yang; Feng, Yao; Yi, Tu; Shengrong, Sun; Xingrui, Li; Chuang, Chen title: Patient reported outcomes of breast cancer patients during the COVID-19 outbreak in the epicenter of China: A cross sectional survey study date: 2020-06-07 journal: Clin Breast Cancer DOI: 10.1016/j.clbc.2020.06.003 sha: doc_id: 325901 cord_uid: gucnce1f PURPOSE: Special attention should be paid to psychological status of breast cancer patients especially those with poor general condition, treatment discontinuation, aggressive molecular subtypes and metastatic breast cancer.
    keywords: breast; cancer; china; covid-19; outbreak; patients
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        item: #5524 of 7819
          id: cord-325933-1qvpofvp
      author: Samrah, Shaher M
       title: Depression and Coping Among COVID-19-Infected Individuals After 10 Days of Mandatory in-Hospital Quarantine, Irbid, Jordan
        date: 2020-10-06
       words: 3514
      flesch: 42
     summary: Symptoms of depression were common among both symptomatic and asymptomatic quarantined COVID-19 patients. Although variable degrees of fear, anxiety, anger, and depression are suspected to be observed in COVID-19-infected population during their quarantine, most studies in the literature focused on the psychosocial disturbances among health-care providers and potential contacts of COVID-19 patients.
    keywords: care; covid-19; depression; health; patients; quarantine; study; symptoms
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        item: #5525 of 7819
          id: cord-325938-hb6fvgem
      author: Dobler, Claudia C.
       title: Non-Invasive Positive Pressure Ventilation in Patients With COVID-19
        date: 2020-10-08
       words: 2559
      flesch: 31
     summary: Often requires sedation, inability for patient to communicate and may have increased association with delirium and posttraumatic stress disorder • May be associated with longer hospitalization and higher mortality compared to patients who have avoided intubation on NIPPV d • Risk of vocal cord damage, procedural hypotension, and other adverse effects directly associated with placement of an endotracheal tube • Potential for lung injury associated with positive endexpiratory pressure • High risk of viral transmission during intubation (can be limited by techniques of apneic oxygenation and rapid sequence intubation with paralysis) and also during Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19 Covid-19 Does Not Lead to a Typical Acute Respiratory Distress Syndrome Association of Home Noninvasive Positive Pressure Ventilation With Clinical Outcomes in Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-analysis Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) Guidance for the role and use of non-invasive respiratory support in adult patients with COVID19 (confirmed or suspected) National Institutes of Health (NIH). From an American Thoracic Society-led International Task Force Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Use of non-invasive ventilation for patients with COVID-19: a cause for concern?
    keywords: acute; covid-19; intubation; nippv; patients; ventilation
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        item: #5526 of 7819
          id: cord-325948-wszd7pq4
      author: Bhasin, Ajay
       title: Is BMI higher in younger patients with COVID‐19? Association between BMI and COVID‐19 hospitalization by age
        date: 2020-07-01
       words: 1651
      flesch: 54
     summary: Remainder of characteristics are listed in No differences in BMI were found between groups for hospitalized patients without COVID-19, with exception that those over 50 years of age had higher BMI than those under 50 years of age when without DM or hypertension (the opposite of the COVID-19 trend). We did not observe the same associations between BMI and age for hospitalized patients without COVID-19.
    keywords: age; covid-19; patients
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        item: #5527 of 7819
          id: cord-325956-1kxxg0s9
      author: Potluri, Rahul
       title: Making sense of the Global Coronavirus Data: The role of testing rates in understanding the pandemic and our exit strategy
        date: 2020-04-11
       words: 3969
      flesch: 57
     summary: From this source, we obtained many parameters including the number of country wise COVID-19 cases, deaths, tests performed, cases per million population, deaths per million population and tests per million population. Given the pandemic course of COVID-19, it has become common practice to compare its spread in different countries using case fatality rates 3, 4, 7, 13 .
    keywords: countries; license; medrxiv; number; preprint; test
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        item: #5528 of 7819
          id: cord-325966-0g7a9s5z
      author: Shih, Hsin-I.
       title: Fighting COVID-19: a quick review of diagnoses, therapies, and vaccines
        date: 2020-05-30
       words: 7334
      flesch: 33
     summary: For COVID-19 patients, fever and cough are the two most common symptoms, and some patients might also suffer from sputum production, sore throat, headache, myalgia/arthralgia, rhinorrhea, and diarrhea An earlier study demonstrated that hydroxychloroquine was significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect was strengthened by azithromycin [25] .
    keywords: antibodies; bcg; cells; coronavirus; cov-2; covid-19; immunity; infection; patients; protein; rna; sars; syndrome; treatment; vaccination; vaccine; virus
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        item: #5529 of 7819
          id: cord-325971-volbaipv
      author: Neupane, Karun
       title: Potential Treatment Options for COVID-19: A Comprehensive Review of Global Pharmacological Development Efforts
        date: 2020-06-26
       words: 3026
      flesch: 40
     summary: Several drugs are being tested in the trials, and the United States Food and Drugs Administration (FDA) has given Emergency Use Authorization (EUA) for remdesivir to treat COVID-19 patients on May 1, 2020 The clinical management of COVID-19 patients is focused on alleviating clinical symptoms by general and symptom-specific supportive care
    keywords: coronavirus; covid-19; patients; remdesivir; results; sars; treatment; trials
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        item: #5530 of 7819
          id: cord-325988-of3exw6a
      author: Salman, Muhammad
       title: Knowledge, attitude and preventive practices related to COVID-19: a cross-sectional study in two Pakistani university populations
        date: 2020-05-09
       words: 2549
      flesch: 49
     summary: Overall, it was encouraging to see that the majority of university students and employees had good COVID-19 knowledge and attitudes. Responses of the 416 study participants regarding COVID-19 knowledge are shown in Table 2 .
    keywords: covid-19; knowledge; participants; practices; study; university
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        item: #5531 of 7819
          id: cord-326010-8f891ocp
      author: Wang, Yibin
       title: Using “old” medications to fight new COVID-19: Re-purposing with a purpose
        date: 2020-07-18
       words: 755
      flesch: 33
     summary: Nevertheless, it is emerging that several therapies originally approved to treat preexisting conditions may bring clinical benefits to reduce death and severe complications in COVID-19 patients (Figure) . For researchers, these newly observed benefits of ACEi/ARB and Statins in COVID-19 patients also raise many questions about the viral-host interaction at molecular, cellular and organ levels.
    keywords: angiotensin; covid-19; patients
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        item: #5532 of 7819
          id: cord-326017-qw4qynqv
      author: Laskar, Partha
       title: “Tomorrow Never Dies”: Recent Advances in Diagnosis, Treatment, and Prevention Modalities against Coronavirus (COVID-19) amid Controversies
        date: 2020-08-06
       words: 14817
      flesch: 35
     summary: Thus, early, rapid, and accurate diagnosis of COVID-19 patients is becoming very crucial to control the sources of infection and to prevent further community spread. Such tests have proven lung histology (lung damage or holes/honeycomb-like appearance) of COVID-19 patients [70] .
    keywords: 2019; amplification; antiviral; cases; coronavirus; cov-2; covid-19; data; detection; development; disease; drug; health; human; iii; infection; methods; number; pandemic; patients; pcr; pneumonia; research; rna; sars; time; treatment; use
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        item: #5533 of 7819
          id: cord-326023-vwukiwe4
      author: Leung, Char
       title: Risk factors for predicting mortality in elderly patients with COVID-19: a review of clinical data in China
        date: 2020-04-27
       words: 2688
      flesch: 47
     summary: While dyspnoea and chest pain/discomfort were more commonly seen in deceased patients as they represented severe pneumonia, fever was more prominent in surviving patients. Two searches were performed, one with the search terms death, pneumonia and age for the clinical data of deceased patients whereas the other with the search terms discharge, pneumonia and age for the clinical data of surviving patients that served as controls.
    keywords: clinical; covid-19; mortality; patients; study
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        item: #5534 of 7819
          id: cord-326029-oya0fc6d
      author: Fuentenebro, Pablo
       title: Will philanthropy save us all? Rethinking urban philanthropy in a time of crisis
        date: 2020-09-22
       words: 3783
      flesch: 45
     summary: The solution to failed philanthropy is more of it; the failure of philanthropy is its success (2012, (195) (196) . Rethinking urban philanthropy in a time of crisis date: 2020-09-22 journal: Geoforum DOI: 10.1016/j.geoforum.2020.07.005 sha: doc_id: 326029 cord_uid: oya0fc6d In the wake of the COVID-19 pandemic, philanthropy has been quick to react to the call for help from Governments and International Organisations.
    keywords: aid; covid-19; crisis; new; pandemic; philanthropy; society; super; world
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        item: #5535 of 7819
          id: cord-326051-p9017jx8
      author: Lopes, Agnaldo José
       title: Comparison Between Lung Ultrasound and Computed Tomographic Findings in Patients With COVID‐19 Pneumonia
        date: 2020-09-30
       words: 4703
      flesch: 44
     summary: 12 Despite the numerous advantages of LUS, there is still not sufficiently clear information to determine its diagnostic value in COVID-19, especially when comparing ultrasound (US) signs with chest CT findings. Although chest CT findings may be normal or indeterminate during the very early stage of COVID-19, the initial findings usually include only GGO areas, and then areas of consolidation appear in the lungs with disease progression.
    keywords: areas; covid-19; disease; findings; lung; lus; patients; pneumonia
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        item: #5536 of 7819
          id: cord-326058-x40l8ljx
      author: Thompson, H. A.
       title: The projected impact of mitigation and suppression strategies on the COVID-19 epidemic in Senegal: A modelling study
        date: 2020-07-04
       words: 4695
      flesch: 43
     summary: Coronavirus disease (COVID-19) Situation Report -147 Virus exponses gaping holes in Africa's health systems Ministère de la Santé et de l'Action Sociale Decree n ° 2020-830 of 23 March 2020 proclaiming a state of emergency on the national territory Response strategies for COVID-19 epidemics in African settings: a mathematical modelling study The impact of COVID-19 and strategies for mitigation and suppression in low-and middle-income countries The relatively young and rural population may limit the spread and severity of COVID-19 in Africa: a modelling study The potential effects of widespread community transmission of SARS-CoV-2 infection in the WHO African Region: a predictive model How generation intervals shape the relationship between growth rates and reproductive numbers A new framework and software to estimate time-varying reproduction numbers during epidemics Social contact structures and time use patterns in the Manicaland Province of Zimbabwe Estimates of the severity of coronavirus disease 2019: a model-based analysis. We calibrate a dynamical model of COVID-19 transmission to these data to investigate the potential impact of different mitigation and suppression strategies on mortality and health system capacity and explore possible future trajectories of the still nascent epidemic in Senegal.
    keywords: capacity; cases; covid-19; figure; healthcare; measures; senegal; suppression; transmission
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        item: #5537 of 7819
          id: cord-326081-9gh6tj7g
      author: Jaiswal, A. K.
       title: COVIDPEN: A Novel COVID-19 Detection Model using Chest X-Rays and CT Scans
        date: 2020-07-10
       words: 4968
      flesch: 49
     summary: Past work demonstrated few methods [7] , [8] to diagnose diseases by means of providing decisions [9] and exploratory insights to X-ray images. Detection of sars-cov-2 in different types of clinical specimens Chest ct for typical 2019-ncov pneumonia: relationship to negative rt-pcr testing Clinical features of patients infected with 2019 novel coronavirus in wuhan, china Imaging profile of the covid-19 infection: radiologic findings and literature review Artificial intelligence distinguishes covid-19 from community acquired pneumonia on chest ct Efficientnet: Rethinking model scaling for convolutional neural networks Computer-aided diagnosis in chest radiography Xray categorization and retrieval on the organ and pathology level, using patch-based visual words Predicting active pulmonary tuberculosis using an artificial neural network A new 2.5 d representation for lymph node detection using random sets of deep convolutional neural network observations Deep convolutional neural networks for computer-aided detection: Cnn architectures, dataset characteristics and transfer learning Semisupervised learning for cancer detection of lymph node metastases Spinenet: automatically pinpointing classification evidence in spinal mris A novel transfer learning based approach for pneumonia detection in chest x-ray images Chexnet: Radiologistlevel pneumonia detection on chest x-rays with deep learning Identifying pneumonia in chest x-rays: A deep learning approach A transfer learning method with deep residual network for pediatric pneumonia diagnosis An automatic method for lung segmentation and reconstruction in chest x-ray using deep neural networks Deep learning-based recognizing covid-19 and other common infectious diseases of the lung by chest ct scan images Covid-19: automatic detection from x-ray images utilizing transfer learning with convolutional neural networks Test-time augmentation for deep learning-based cell segmentation on microscopy images Focal loss for dense object detection Very deep convolutional networks for large-scale image recognition Deep residual learning for image recognition Densely connected convolutional networks A disciplined approach to neural network hyperparameters: Part 1-learning rate, batch size, momentum, and weight decay Covid-ct-dataset: A ct scan dataset about covid-19 Covid-19 image data collection why should i trust you?
    keywords: chest; covid-19; images; learning; model; network; neural; test
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        item: #5538 of 7819
          id: cord-326085-2dt758qj
      author: Patanavanich, Roengrudee
       title: Smoking Is Associated With COVID-19 Progression: A Meta-analysis
        date: 2020-05-11
       words: 2235
      flesch: 48
     summary: Smoking is associated with COVID-19 disease progression. A total of 907 studies were retrieved through the search, of which 19, 8-26 16 from China, 1 from Korea, and 2 from the United States, included data on smoking behavior and COVID-19 disease progression (Supplementary Table S1 ).
    keywords: analysis; covid-19; patients; progression; smoking
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        item: #5539 of 7819
          id: cord-326089-8234mcdk
      author: Sweid, Ahmad
       title: Incidence of Acute Ischemic Stroke and Rate of Mechanical Thrombectomy During the COVID-19 Pandemic in a Large Tertiary Care Telemedicine Network
        date: 2020-06-13
       words: 560
      flesch: 33
     summary: www.worldstroke.org/news-and-blog/news/stroke-care-and-the-covid19-pandemic Accessed 5 Cardiovascular considerations for patients, health care workers, and health systems during the coronavirus disease 2019 (COVID-19) pandemic Thromboinflammation and the hypercoagulability of COVID-19 Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19 Temporary Emergency Guidance to US Stroke Centers During the COVID-19 Pandemic Society of NeuroInterventional Surgery recommendations for the care of emergent neurointerventional patients in the setting of covid-19 The authors have no conflict of interest to report. 1, 2 The higher incidence of COVID-19 patients in the overall stroke group can be supported by recent theories that systemic COVID-19 may contribute to a hyper-thrombotic state and increase the risk of AIS.
    keywords: covid-19; patients
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        item: #5540 of 7819
          id: cord-326113-r5a7qoks
      author: Mellis, Alexandra M.
       title: COVID-19-related treatment service disruptions among people with single- and polysubstance use concerns
        date: 2020-10-21
       words: 1598
      flesch: 38
     summary: An Epidemic in the Midst of a Pandemic: Opioid Use Disorder and COVID-19 COVID-19 Pandemic: Impact on psychiatric care in the United States Addiction psychiatry and COVID-19: impact on patients and service provision Polysubstance use: Diagnostic challenges, patterns of use and health Low Barrier Tele-Buprenorphine in the Time of COVID-19: A Case Report COVID-19 Pandemic Impact on Patients, Families and Individuals in Recovery from Substance Use Disorder The COVID-19 pandemic and its impact on substance use: Implications for prevention and treatment Polysubstance use was also associated with reported changes in treatment or recovery support service access due to COVID-19 (39% among people reporting polysubstance use versus 26% among those with single substance use).
    keywords: access; services; treatment; use
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        item: #5541 of 7819
          id: cord-326148-9wpxm5of
      author: Van Walle, I.
       title: Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid, antigen and antibody tests up to 22 August 2020
        date: 2020-09-18
       words: 3791
      flesch: 40
     summary: Antibody test sensitivity results below the threshold days after onset were excluded. After exclusion of antibody test sensitivity results ≤14 dpo and ineligible specificity results, a total of 38202 and 56537 index test results remained for calculation of sensitivity and specificity, respectively.
    keywords: acid; performance; preprint; results; sensitivity; specificity; tests
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        item: #5542 of 7819
          id: cord-326150-cf4rlqe5
      author: Carrascosa, J M
       title: Manifestaciones cutáneas en el contexto de la infección por SARS-CoV-2 (COVID-19)
        date: 2020-08-31
       words: 2446
      flesch: 30
     summary: El tiempo de latencia entre el inicio de los síntomas de la COVID-19 y el desarrollo de la clínica cutánea fue relativamente corto, de 3 días (de 2 a 12). r o o f clínico completo de la COVID-19, con manifestaciones generales y respiratorias 19 .
    keywords: como; con; covid-19; del; infección; las; lesiones; los; pacientes; por; que; sars; una
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        item: #5543 of 7819
          id: cord-326154-01es0zv4
      author: Aggarwal, Gaurav
       title: Cardiovascular Safety of Potential Drugs for the Treatment of Coronavirus Disease 2019
        date: 2020-05-16
       words: 2306
      flesch: 36
     summary: In some of these cases, baseline QT interval was found to be mildly prolonged and hence QT interval is such patients should be closely monitored to prevent risk of ventricular arrhythmias. Cardiac magnetic resonance imaging (cMRI) in such patients has shown patchy delayed contrast enhancement 6, 10 .
    keywords: azithromycin; covid-19; disease; patients; risk; treatment
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        item: #5544 of 7819
          id: cord-326169-delehk6x
      author: CJ Jorgensen, Sarah
       title: Baricitinib: A review of pharmacology, safety and emerging clinical experience in COVID‐19
        date: 2020-06-15
       words: 2711
      flesch: 32
     summary: All rights reserved 651 46 Abnormal coagulation parameters are associated with poor 655 prognosis in patients with novel coronavirus pneumonia Difference of coagulation features between severe pneumonia 657 induced by SARS-CoV2 and non-SARS-CoV2 Hypercoagulability of COVID-19 patients in Intensive 659 Care Unit. JAK-inhibitors that are less selective for JAK2 may act counts in COVID-19 patients Besides common side effects and changes in laboratory parameters, baricitinib has been associated 422 with serious adverse effects including infections, thrombosis, malignancy, gastrointestinal 423 perforations, and major cardiovascular events.
    keywords: article; baricitinib; copyright; covid-19; jak; patients; sars; treatment
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        item: #5545 of 7819
          id: cord-326171-xr2ufvyv
      author: Bhoori, Sherrie
       title: COVID-19 in long-term liver transplant patients: preliminary experience from an Italian transplant centre in Lombardy
        date: 2020-04-09
       words: 840
      flesch: 44
     summary: Data on COVID-19 in liver transplant patients are scarce. We recognise the intrinsic limitations of this case series (ie, the small sample size, the unavailability of the exact number of COVID-19 positive patients, and the associated difficulty in accurately calculating the case-fatality rate) and the consequent urgent need of collecting data for further studies to draw more solid conclusions.
    keywords: covid-19; patients
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        item: #5546 of 7819
          id: cord-326173-3x435v6q
      author: Beck, Matthew J.
       title: Insights into the impact of COVID-19 on household travel and activities in Australia – The early days of easing restrictions
        date: 2020-08-18
       words: 11517
      flesch: 49
     summary: With respect to walking, more respondents reported an increase in Wave 2 (27%) than a decrease (12%), with younger respondents more likely to have reported an increase. In terms of future use, for each of the active modes more respondents report an intention to increase their use of that activity than decrease: 34% vs 4% for walking (with younger respondents more likely to plan an increase in use); 14% vs 5% for walking (with younger respondents more likely to plan an increase in use); and 12% versus 4% for bicycling.
    keywords: average; covid-19; days; figure; home; income; number; respondents; transport; travel; wave; work; working
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        item: #5547 of 7819
          id: cord-326185-gjte739i
      author: Mukherjee, Pratik
       title: Adaptability and responsiveness: keys to operational measures in a regional hospital radiology department during the current COVID-19 pandemic
        date: 2020-06-19
       words: 6159
      flesch: 46
     summary: Internet Walk-Up X-ray Booth Offers Quick Scans to COVID-19 Patients Additional staff (radiologists, radiographers, nurses and other radiology department support staff) were rostered over the weekends to clear the extra workload.
    keywords: cases; covid-19; department; disease; hospital; infection; pandemic; patients; radiology; singapore; staff
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        item: #5548 of 7819
          id: cord-326189-41t2sshy
      author: García-Colón, Ismael
       title: The COVID-19 spring and the expendability of guestworkers
        date: 2020-07-29
       words: 3528
      flesch: 42
     summary: Meanwhile, in the USA, the Trump Administration is increasing the rhetoric of nativism and pandemic to implement aggressive immigration bans that affect other industries and arguing that these policies benefit US workers by reducing job competition from immigrants. If the supply of local workers available to work under the wage and conditions set forth by growers and government officials was insufficient, the US Department of Labor certified the use of guestworkers.
    keywords: covid-19; employers; farmworkers; government; guestworkers; labor; usa; workers; working
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        item: #5549 of 7819
          id: cord-326210-216atclj
      author: Sturmberg, Joachim P.
       title: COVID‐19 – how a pandemic reveals that everything is connected to everything else
        date: 2020-07-06
       words: 2759
      flesch: 44
     summary: Each of these approaches has its own dynamics affecting individuals, communities, health systems, the economy, and the nation as a whole-new patterns emerge that become understandable with increasing knowledge (Figure 1 ). For example, imposing community-wide (self-) isolation entails that almost all activities stop, destroying the economy and resulting in high unemployment, poverty, and increasing disease burden, while implementing strategies to slow down the spread of infection will not guarantee that we will not overwhelm health systems or stabilize the pandemic.
    keywords: covid-19; disease; dynamics; health; pandemic; policy; system
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        item: #5550 of 7819
          id: cord-326220-uosjmht0
      author: Gaskell, Jen
       title: Covid‐19 and the Blunders of our Governments: Long‐run System Failings Aggravated by Political Choices
        date: 2020-08-11
       words: 5777
      flesch: 45
     summary: Firstly, we develop the idea that governance failures reflect not only policy choice errors but also structural features of governance systems that make shortcomings more likely. We argue that outcome was possible in part because those countries had governance systems with a greater depth and spread of decision-making points, resources, and the capacity to use them.
    keywords: capacity; countries; covid-19; crisis; failure; governance; government; levels; policy; response; system
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        item: #5551 of 7819
          id: cord-326272-ya3r0h1t
      author: Dobesh, Paul P.
       title: Coagulopathy, Venous Thromboembolism, and Anticoagulation in Patients with COVID‐19
        date: 2020-10-01
       words: 8611
      flesch: 41
     summary: All rights reserved There have also been observational trials that have compared rates of VTE in COVID-19 patients to historical controls without COVID-19 (Table 3) . The rate of PE was 3-fold higher in COVID-19 patients compared to those without, but was also more than 2-fold higher than influenza patients specifically during the same time frame.
    keywords: anticoagulation; article; coronavirus; covid-19; dimer; disease; icu; patients; prophylaxis; risk; sars; thrombosis; venous; vte
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        item: #5552 of 7819
          id: cord-326321-9n345vyu
      author: Moreno, Cinthia Baldallo
       title: Infección por COVID-19 en una paciente con síndrome urticarial hipocomplementémico y vasculitis ANCA MPO en hemodiálisis tratada con omalizumab
        date: 2020-07-27
       words: 1072
      flesch: 42
     summary: y de los basófilos y mastocitos 4 . Describimos el primer caso de COVID-19 en una paciente en hemodiálisis (HD) tratada con omalizumab. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study COVID-19 in Hemodialysis Patients: A Report of 5 Cases Benefits and Harms of Omalizumab Treatment in Adolescent and Adult Patients with Chronic Idiopathic (Spontaneous) Urticaria: A Meta-analysis of real-world Evidence Chronic kidney disease is associated with severe coronavirus disease 2019 (COVID-19) infection Situación de la infección por SARS-CoV-2 en pacientes en tratamiento renal sustitutivo Informe del Registro COVID-19 de la Sociedad Española de Nefrología Baseline Characteristics and Outcomes of 1591 Patients Infected with SARS-CoV-2 Admitted to ICUs of the Lombardy Region
    keywords: con; covid-19; por; que; una
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        item: #5553 of 7819
          id: cord-326331-g4o3forj
      author: Rai, Ansaar T
       title: Neuroendovascular clinical trials disruptions due to COVID-19 potential future challenges and opportunities
        date: 2020-06-30
       words: 3463
      flesch: 39
     summary: All were involved in neurovascular clinical trials as site principal investigators and six were leading clinical trials as national principal investigators. Similar guidelines were issued by the European Medicines Agency on the management of clinical trials during the COVID-19 pandemic on April 28, 2020 (https:// ec.
    keywords: covid-19; enrollment; pandemic; research; sites; study; survey; trials
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        item: #5554 of 7819
          id: cord-326339-46imi33v
      author: Tang, A. C. Y.
       title: Associations between Demographic Characteristics, Perceived Threat, Perceived Stress, Coping Responses and Adherence to COVID-19 Prevention Measures among Healthcare Students in China: A Cross-Sectional Survey with Implications for the Control of COVID-19
        date: 2020-07-16
       words: 6885
      flesch: 45
     summary: This result indicates that compared to Hong Kong students, Fujian students were more willing to engage in social distancing. This result means that Fujian students perceived less threat and adopted more empathetic responding than Hong Kong students.
    keywords: compliance; covid-19; distancing; health; hygiene; license; measures; preprint; students; study
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        item: #5555 of 7819
          id: cord-326348-3zc62lin
      author: Bachtiger, P.
       title: Belief of Previous COVID-19 Infection and Unclear Government Policy are Associated with Reduced Willingness to Participate in App-Based Contact Tracing: A UK-Wide Observational Study of 13,000 Patients
        date: 2020-06-06
       words: 4204
      flesch: 46
     summary: [0.59 -0.91]) in app based contact tracing (Table 3 ). The timing of the questionnaire coincided with changes in government announcements of lockdown policy which for many created substantial uncertainty, and this might be expected to reduce motivation, and possibly trust, as an explanation for the observed association between unwillingness for app based contact tracing and difficulty understanding government advice.
    keywords: app; contact; covid-19; government; june; license; medrxiv; preprint
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        item: #5556 of 7819
          id: cord-326354-fhafg41x
      author: Pesavento, Raffaele
       title: The hazard of (sub)therapeutic doses of anticoagulants in non‐critically ill patients with Covid‐19: the Padua province experience
        date: 2020-07-21
       words: 2836
      flesch: 36
     summary: All rights reserved Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected: interim guidance A Novel Coronavirus from Patients with Pneumonia in China A novel coronavirus outbreak of global health concern Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-Accepted Article This article is protected by copyright. The results of prospective randomized studies, including severe patients, are warranted.
    keywords: antithrombotic; bleeding; covid-19; doses; patients; study
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        item: #5557 of 7819
          id: cord-326355-oyspjx20
      author: Auðardóttir, Auður Magndís
       title: Chaos ruined the children’s sleep, diet and behaviour: Gendered discourses on family life in pandemic times
        date: 2020-08-17
       words: 6872
      flesch: 55
     summary: COVID-19, motherhood, neoliberal governmentality, parental practices, story completion In February 2020, the worldwide pandemic of COVID-19 reached Iceland. Mothering through ethical consumption Intensive mothering in hard times: Foucauldian ethical selfformation and cruel optimism The constrained use of irony in U.S. Congressional Hearings on Immigration On mothering and being mothered: A personal reflection on women's productivity during COVID-19 Editorial introduction to the Special Issue: Using story completion methods in qualitative research All that glitters is not gold: Shrinking and bending gender equality in rankings and nation branding Iceland: from reluctance to frast-track engineering Beauty surveillance: The digital self-monitoring cultures of neoliberalism Introduction.
    keywords: anna; children; covid-19; family; karl; life; participants; stories; story; women; work
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        item: #5558 of 7819
          id: cord-326369-ur67a7jv
      author: Kokane, P. P.
       title: Understanding the Incidence of Covid-19 among the police force in Maharashtra through a mixed approach
        date: 2020-06-16
       words: 4559
      flesch: 51
     summary: https://doi.org/10.1101/2020.06.11.20125104 doi: medRxiv preprint the well-being of police personnel so that efficiency and preparedness of police force will be utilized effectively in future for such type of pandemic crisis. Further, the long-time fight against Covid-19 had drained police force mentally and physically and this put them in higher risk.
    keywords: cases; covid-19; license; lockdown; medrxiv; pandemic; police; preprint; study
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        item: #5559 of 7819
          id: cord-326393-gxy1w0qk
      author: Martino, Marcello Di
       title: CIRUGÍA ELECTIVA DURANTE LA PANDEMIA POR SARS-CoV-2 (COVID-19): ANÁLISIS DE MORBIMORTALIDAD Y RECOMENDACIONES SOBRE PRIORIZACIÓN DE LOS PACIENTES Y MEDIDAS DE SEGURIDAD
        date: 2020-04-29
       words: 4244
      flesch: 37
     summary: Se analizó la tasa de contagio por COVID-19, la gravedad de la infección respiratoria según la Brescia Respiratory COVID-19 Severity Scale, las medidas terapéuticas adoptadas y las complicaciones postoperatorias globales. Hubo 3 (1,4%) exitus, todos debidos a progresión de la infección respiratoria.
    keywords: actividad; cirugía; complicaciones; con; cov-2; covid-19; del; infección; infection; las; los; pacientes; pandemia; patients; por; que; quirúrgica; respiratoria; sars; según; una
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        item: #5560 of 7819
          id: cord-326400-yl3pisxt
      author: Bansal, Devanshu
       title: Urological Surgeries During Exit from National Lockdown During COVID-19 Pandemic
        date: 2020-09-07
       words: 517
      flesch: 40
     summary: Effect of COVID-19 related lockdown on ophthalmic practice and patient care in India: results of a survey Comparison of different exit scenarios from the lock-down for COVID-19 epidemic in the UK and assessing uncertainty of the predictions. Once planned for surgery, every patient should be screened for symptoms and tested for COVID-19.
    keywords: covid-19; hospital
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        item: #5561 of 7819
          id: cord-326406-n0qi6gs8
      author: Creed, Marina
       title: Mild COVID-19 infection despite chronic B cell depletion in a patient with aquaporin-4-positive neuromyelitis Optica spectrum disorder.
        date: 2020-05-19
       words: 1810
      flesch: 39
     summary: Clinical Characteristics of Coronavirus Disease 2019 in China SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease COVID-19: consider cytokine storm syndromes and immunosuppression Breadth of concomitant immune responses prior to patient recovery: a case report of non-severe COVID-19 Characteristics of peripheral lymphocyte subset alteration in COVID-19 pneumonia Neutrophil-to-lymphocyte ratio and lymphocyte-to-C-reactive protein ratio in patients with severe coronavirus disease 2019 (COVID-19): This suggestion is supported by reports of cases of mild disease in a patient with long term corticosteroid use 8 but there is a need for prospective randomized trials to determine if immunosuppression or immunomodulation may be protective from worse outcome of COVID19.
    keywords: cov-2; covid-19; disease; patients; rituximab; sars
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        item: #5562 of 7819
          id: cord-326413-rhvsdpyk
      author: Nuzzolese, Emilio
       title: Dental autopsy recommendations in SARS-CoV-2 infected cases
        date: 2020-05-04
       words: 2319
      flesch: 40
     summary: The most important aspect of protection for dental autopsy personnel is the correct use of personal protective equipment and training prior to conducting any autopsy and dental autopsy [9e12]. key: cord-326413-rhvsdpyk authors: Nuzzolese, Emilio; Pandey, Hemlata; Lupariello, Francesco title: Dental autopsy recommendations in SARS-CoV-2 infected cases date: 2020-05-04 journal: Forensic Science International DOI: 10.1016/j.fsisyn.2020.04.004 sha: doc_id: 326413 cord_uid: rhvsdpyk Abstract Unidentified human remains with unknown medical history can always pose biological hazards to forensic pathologists and odontologists, including hepatitis C, HIV infection, Middle East respiratory syndrome (MERS), hemorrhagic fever viruses such as Ebola, meningitis and now Sars-Cov2.
    keywords: autopsy; covid-19; dental; human; identification; sars
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        item: #5563 of 7819
          id: cord-326421-ng1uhwgs
      author: Zalesky, C. Christopher
       title: Emergency Medicine Physician Work Environments During the COVID-19 Pandemic
        date: 2020-09-07
       words: 1061
      flesch: 47
     summary: Survey data were collected from April 29 to May 13, 2020. The authors would like to thank the EMRA Board of Directors for their support of the study, and EMRA staff members Mr. Todd Downing and Ms. Cathey Wise, who facilitated survey distribution.
    keywords: covid-19; emergency; physicians; survey
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        item: #5564 of 7819
          id: cord-326427-06djb0sd
      author: Cao, Dongmei
       title: Vaginal delivery in women with COVID-19: report of two cases
        date: 2020-10-02
       words: 2591
      flesch: 48
     summary: key: cord-326427-06djb0sd authors: Cao, Dongmei; Chen, Miaomiao; Peng, Min; Yin, Heng; Sun, Guoqiang title: Vaginal delivery in women with COVID-19: report of two cases date: 2020-10-02 journal: BMC Pregnancy Childbirth DOI: 10.1186/s12884-020-03281-4 sha: doc_id: 326427 cord_uid: 06djb0sd BACKGROUND: During the ongoing global outbreak of COVID-19, pregnant women who are susceptible to COVID-19 should be highly concerned. As pregnant women are susceptible to COVID-19 and some common obstetrical adverse events, such as preterm premature rupture of membranes (PPROM), preterm birth, fetal growth restriction (FGR), and neonatal death, are associated with maternal pneumonias [4] [5] [6] , pregnant women should be highly concerned by obstetricians [7] .
    keywords: cov-2; covid-19; infection; mother; sars
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        item: #5565 of 7819
          id: cord-326468-xcy7v1tf
      author: Mehta, R. M.
       title: A shorter symptom-onset to remdesivir treatment (SORT) interval is associated with a lower mortality in moderate-to-severe COVID-19: A real-world analysis
        date: 2020-11-10
       words: 3701
      flesch: 47
     summary: Although not statistically significant, the median LOHS was numerically lower in patients with SORT interval ≤9 days compared with >9 days (10 v 12 days; P = .34). Patients with SORT interval ≤9 days showed favorable outcomes with lower mortality (18.1% vs 33.7%) compared with SORT interval >9 days, with the difference driven largely by the severe subset.
    keywords: covid-19; days; interval; mortality; patients; remdesivir; sort
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        item: #5566 of 7819
          id: cord-326497-458mnekj
      author: Schaible, Jan
       title: Sharp margin and geographic shape: systematic evaluation of two novel CT features in COVID-19 pneumonia
        date: 2020-07-08
       words: 2799
      flesch: 47
     summary: All patients with reverse transcription polymerase chain reaction proven COVID-19 pneumonia and chest CT between March first and April 15, 2020 were retrospectively identified from two tertiary care hospitals in Germany. This morphology is otherwise not often seen in chest CT and would be strongly suggestive for COVID-19 pneumonia during the pandemic.
    keywords: covid-19; opacifications; patients; pneumonia; shape
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        item: #5567 of 7819
          id: cord-326498-8oa5gkrp
      author: Gemmati, Donato
       title: COVID-19 and Individual Genetic Susceptibility/Receptivity: Role of ACE1/ACE2 Genes, Immunity, Inflammation and Coagulation. Might the Double X-Chromosome in Females Be Protective against SARS-CoV-2 Compared to the Single X-Chromosome in Males?
        date: 2020-05-14
       words: 9893
      flesch: 30
     summary: Firstly, ADAM17 by promoting the detaching of ACE2 cell receptor might contribute by downregulating the ACE2/Ang1-7/Mas axis, and in a sex-oriented perspective, SRY (Y-chromosome) and SOX3 (Xchromosome) both by upregulating AGT, and downregulating ACE2, AT2, and MAS. Firstly, ADAM17 by promoting the detaching of ACE2 cell receptor might contribute by downregulating the ACE2/Ang1-7/ Mas axis, and in a sex-oriented perspective, SRY (Y-chromosome) and SOX3 (X-chromosome) both by upregulating AGT, and downregulating ACE2, AT2, and MAS.
    keywords: ace1; ace2; angiotensin; cells; chromosome; converting; coronavirus; covid-19; disease; enzyme; expression; females; gene; immune; infection; patients; receptor; sars; sex
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        item: #5568 of 7819
          id: cord-326506-8jckdecg
      author: Chandratre, Sonal
       title: Medical Students and COVID-19: Challenges and Supportive Strategies
        date: 2020-06-24
       words: 1291
      flesch: 42
     summary: Medical students are experiencing increasing anxiety due to the COVID-19 disruption. Medical students show higher rates of depression, suicidal ideation, and stigmatization around depression and are less likely to seek support.
    keywords: covid-19; health; medical; students
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        item: #5569 of 7819
          id: cord-326509-1cpybatu
      author: Varkey, Rittu S.
       title: Socioeconomic determinants of COVID‐19 in Asian countries: An empirical analysis
        date: 2020-10-23
       words: 4349
      flesch: 48
     summary: key: cord-326509-1cpybatu authors: Varkey, Rittu S.; Joy, Justin; Sarmah, Gargee; Panda, Prasant K. title: Socioeconomic determinants of COVID‐19 in Asian countries: An empirical analysis date: 2020-10-23 journal: J Public Aff DOI: 10.1002/pa.2532 sha: doc_id: 326509 cord_uid: 1cpybatu The spread of coronavirus disease, 2019, has affected several countries in the world including Asian countries. The paper is an attempt to empirically examine the socioeconomic determinants of the occurrence of COVID in Asian countries considering the data as of June 18, 2020, for 42 Asian countries.
    keywords: asian; cases; countries; covid-19; income; number; people; poverty
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        item: #5570 of 7819
          id: cord-326526-evms6810
      author: None
       title: Practice Notes from the AAAI
        date: 2020-06-30
       words: 1415
      flesch: 56
     summary: Some options are: Art of Living e Online Happiness Program for Healthcare Workers Headspace Ten Percent Happier Check out the AAAAI physician wellness toolkit for a broader array of ideas and resources. Visit the AAAAI COVID-19 resources page regularly for updated information to help you and your practice navigate the quickly changing situation and to access the aforementioned resources. Just some of the resources you will find include: The decision to cancel the 2020 AAAAI Annual Meeting was a difficult one, but it was also ultimately the right one.
    keywords: aaaai; practice; resources; year
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        item: #5571 of 7819
          id: cord-326527-j6ihs6jx
      author: Walker, Graham
       title: Psychological Defence Mechanisms during the COVID-19 pandemic: A Case Series
        date: 2020-11-07
       words: 2699
      flesch: 36
     summary: Any perceived stress to an individual can provoke psychological defence mechanisms. This paper aims to describe a range of psychological defence mechanisms encountered within colleagues in relation to the COVID-19 pandemic.
    keywords: covid-19; defence; mechanisms; pandemic
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        item: #5572 of 7819
          id: cord-326532-2ehuuvnx
      author: Götzinger, Florian
       title: COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study
        date: 2020-06-25
       words: 5330
      flesch: 40
     summary: The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical characteristics of a case series of children with coronavirus disease 2019 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children and adolescents: a systematic review SARS-CoV-2 infection in children Epidemiology of COVID-19 among children in China Detection of Covid-19 in children in early Spread of SARS-CoV-2 in the Icelandic population CDC COVID-19 Response Team. The study was conducted in accordance with the Declaration of Helsinki and its subsequent Evidence before this study We searched MEDLINE on May 7, 2020, through the PubMed interface to identify publications describing clinical studies in children with COVID-19.
    keywords: children; cov-2; covid-19; data; disease; icu; individuals; infection; patients; sars; study; support
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        item: #5573 of 7819
          id: cord-326565-s62inw07
      author: Shacham, E.
       title: Association of County-Wide Mask Ordinances with Reductions in Daily CoVID-19 Incident Case Growth in a Midwestern Region Over 12 Weeks
        date: 2020-10-30
       words: 1934
      flesch: 48
     summary: The primary study outcome measurement was daily COVID-19 infection growth rate. As COVID-19 infections occur more often among areas with higher county-level population density per square mile, higher proportion of residents identifying as non-white, and lower median annual household income, 25,6 these variables were included from the 2018, 5-year American Community Survey to control for variations in COVID-19 case growth.
    keywords: counties; county; covid-19; growth; mask
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        item: #5574 of 7819
          id: cord-326568-twv2i3fb
      author: Bruminhent, Jackrapong
       title: Clinical characteristics and risk factors for coronavirus disease 2019 (COVID-19) among patients under investigation in Thailand
        date: 2020-09-15
       words: 4407
      flesch: 45
     summary: COVID-19 patients can present as asymptomatic, mild upper respiratory tract disease or potentially severe pneumonia. Although there was a previous case series of COVID-19 patients who were hospitalized [9] , there has been no study focused on this population.
    keywords: case; cov-2; covid-19; infection; patients; puis; risk; thailand
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        item: #5575 of 7819
          id: cord-326574-ke0iktly
      author: Chew, Alton Ming Kai
       title: Digital Health Solutions for Mental Health Disorders During COVID-19
        date: 2020-09-09
       words: 3761
      flesch: 23
     summary: These factors highlight the urgent need to scale-up and decentralize mental health services to attain a multiplier effect in the provision and accessibility of these services to combat the pandemic-driven surge in mental health disorders (9, 11) . Fortunately, several reports have demonstrated the effectiveness of digital health solutions for various applications, including addressing gaps in mental health services (12) .
    keywords: applications; covid-19; data; digital; disorders; health; impact; pandemic; patients; services; systems
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        item: #5576 of 7819
          id: cord-326584-io2f52kn
      author: Killeen, G.
       title: Why lockdown? Simplified arithmetic tools for decision-makers, health professionals, journalists and the general public to explore containment options for the novel coronavirus
        date: 2020-04-20
       words: 8787
      flesch: 37
     summary: Note, however, that the expected failure of contact tracing, and indeed testing generally, is just one more good reason to contain national COVID-19 epidemics before they progress from emergencies (Figures 1 and 4) into outright catastrophes (Figure 2 ). . Here we present simplified arithmetic models of COVID-19 transmission, control and elimination in user-friendly Shiny and Excel formats that allow non-specialists to explore, query, critique and understand the containment decisions facing their country and the world at large.
    keywords: cases; containment; coronavirus; covid-19; disease; epidemic; figure; health; license; lock; national; population; preprint; transmission; weeks
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        item: #5577 of 7819
          id: cord-326600-wg1o85zq
      author: Westley, Suzanne
       title: Productively protecting a cohort of vulnerable plastic surgery trainees in the COVID-19 pandemic
        date: 2020-05-21
       words: 815
      flesch: 48
     summary: key: cord-326600-wg1o85zq authors: Westley, Suzanne; Creasy, Henrietta; Shah, Rupali; Shaharan, Shazrinizam; Mistry, Rikki; Awad, Guirgis; Blair, Jame; Cubison, Tania title: Productively protecting a cohort of vulnerable plastic surgery trainees in the COVID-19 pandemic date: 2020-05-21 journal: J Plast Reconstr Aesthet Surg DOI: 10.1016/j.bjps.2020.05.029 sha: doc_id: 326600 cord_uid: wg1o85zq nan Dear Sir, We submit a letter outlining how at The Queen Victoria Hospital we have so far successfully protected a group of vulnerable plastic surgeons while enabling them to continue to make a valuable contribution to the work of the department, specifically the hand trauma team, during the COVID-19 pandemic. Local assessment of our practice is ongoing but we have found that this model has enabled a cohort of vulnerable plastic surgery trainees to successfully continue to work whilst reducing the risk of exposure to COVID-19 and providing gold standard care for patients.
    keywords: covid-19; hospital; trauma
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        item: #5578 of 7819
          id: cord-326618-0ci9irxl
      author: Chien, Lung-Chang
       title: COVID-19 Outbreak, Mitigation, and Governance in High Prevalent Countries
        date: 2020-09-17
       words: 3568
      flesch: 48
     summary: Among 25 countries with a rising trend through June 15, 52.0% (N = 13) of them were fair governance countries, and 32.0% (N = 8) of them were worse governance countries. In the outbreak period, better governance countries had a more rapid increase but a shorter outbreak period (71.2 days) than countries with fair (93.5 days) and worse (90.8 days) governance.
    keywords: cases; countries; country; covid-19; days; governance; outbreak; period
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        item: #5579 of 7819
          id: cord-326622-r77kqshi
      author: Civil, Ian D
       title: Research and Publishing in the COVID-19 Pandemic
        date: 2020-05-23
       words: 581
      flesch: 33
     summary: Any crisis generates opportunities for new learning and past experience suggests research publication does not slow down during or after a pandemic. However, medical research remains demanding and ever challenging.
    keywords: pandemic; research
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        item: #5580 of 7819
          id: cord-326626-ixxk6plf
      author: Akhtar, Naveed
       title: Characteristics and Comparison of 32 COVID-19 and Non-COVID-19 Ischemic Strokes and historical stroke patients.
        date: 2020-11-02
       words: 2460
      flesch: 43
     summary: Whilst a number of recent reports suggest that COVID-19 associated stroke tends to be severe, there is limited data on the effects of COVID-19 in prospective registries. One-way ANOVAs were performed to see significant mean level differences for all continuous variables according to Pre-COVID-19 ischemic stroke, COVID-19 Negative ischemic stroke and COVID-19 positive categories.
    keywords: admissions; covid-19; ischemic; pandemic; patients; stroke
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        item: #5581 of 7819
          id: cord-326632-botshfa1
      author: Abolfotouh, Mostafa A.
       title: Perception and attitude of healthcare workers in Saudi Arabia with regard to Covid-19 pandemic and potential associated predictors
        date: 2020-09-29
       words: 4136
      flesch: 49
     summary: Multiple regression analysis was used to identify predictors of high concern scores. Predictors of high concern scores were; HCWs of Saudi nationality (p < 0.001), younger age (p = 0.003), undergraduate education (p = 0.044), living with others (p = 0.003) working in the western region (p = 0.003) and direct contact with patients (p = 0.018).
    keywords: concern; covid-19; hcws; high; saudi; score; study
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        item: #5582 of 7819
          id: cord-326635-sdybzl1w
      author: Valika, Taher S.
       title: Return to Normalcy? Principles on Resuming Surgical Services in the COVID-19 Era
        date: 2020-06-11
       words: 1189
      flesch: 55
     summary: Health care practices of the past have evolved into new methods to practice medicine. As a result of the 6-week hiatus in elective surgical care, our department had .800 cases that were postponed.
    keywords: care; covid-19; families; health
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        item: #5583 of 7819
          id: cord-326636-l41qzggh
      author: Fudulu, Daniel P.
       title: Cardiac surgery in the time of the coronavirus
        date: 2020-04-25
       words: 1516
      flesch: 55
     summary: To adapt to these exceptional circumstances, cardiac surgeons had to change their practice significantly. 4 Some of us might have thought that cardiac surgeons will not be in the Covid-19 battle frontline.
    keywords: covid-19; pandemic; surgeons; surgery
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        item: #5584 of 7819
          id: cord-326643-obfvi3ms
      author: Lo Giudice, Roberto
       title: The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) in Dentistry. Management of Biological Risk in Dental Practice
        date: 2020-04-28
       words: 4580
      flesch: 52
     summary: Especially when treating in urgent situations or emergencies during the virus pandemic [6] , clinicians should not underestimate the possibility of infection from asymptomatic patients, and all dental treatment should be considered high-risk. This paper aims to discuss and suggest the most appropriate procedures in every aspect of dental practice to reduce infection risk.
    keywords: contact; droplets; infection; patient; risk; sars; use; virus
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        item: #5585 of 7819
          id: cord-326687-9duu5bbz
      author: Montastruc, Jean-Louis
       title: Serious adverse drug reactions with hydroxychloroquine: a pharmacovigilance study in Vigibase®
        date: 2020-06-06
       words: 844
      flesch: 41
     summary: In Goodman and Gilman's the pharmacological basis of therapeutics Mc Graw Hill New York 13th edition Covid-19: US gives emergency approval to hydroxychloroquine despite lack of evidence Chloroquine and hydroxychloroquine in the management of COVID-19: much kerfuffle but little evidence Uses of pharmacovigilance databases: an overview The QT in patients with COVID-19 treated with hydroxychloroquine and azithromycin Off label use of hydroxychloroquine , azithromycine, lopinavir-ritonavir and chloroquine in COVID-19: a survey of cardiac adverse drug reactions by the French Network of Pharmacovigilance Centers Médicaments utilisés chez les patients atteints du COVID-19 : une surveillance renforcée des effets indésirables. key: cord-326687-9duu5bbz authors: Montastruc, Jean-Louis; Rousseau, Vanessa; Durrieu, Geneviève; Bagheri, Haleh title: Serious adverse drug reactions with hydroxychloroquine: a pharmacovigilance study in Vigibase® date: 2020-06-06 journal:
    keywords: hydroxychloroquine; icsrs; patients
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        item: #5586 of 7819
          id: cord-326692-kq903zbo
      author: Boehning, Dankmar
       title: Estimating the undetected infections in the Covid-19 outbreak by harnessing capture-recapture methods
        date: 2020-04-24
       words: 2575
      flesch: 53
     summary: Of course, if the window is made too small estimates of hidden numbers will only refer to observations made in this window. We provide an efficient, easy to compute and robust lower bound estimator for the number of undetected cases.
    keywords: cases; covid-19; data; number
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        item: #5587 of 7819
          id: cord-326708-92lsnv4g
      author: Craig, J.
       title: Estimating critical care capacity needs and gaps in Africa during the COVID-19 pandemic
        date: 2020-06-04
       words: 3532
      flesch: 36
     summary: Due to lack of data on current national capacities, gaps in hospital bed capacity at outbreak peak were not calculated for two countries (Eswatini and South Sudan), for ICU bed capacity for four countries (Benin, Equatorial Guinea, Madagascar, and Mozambique), and gaps in ventilator capacity were not calculated for six countries (Benin, Republic of the Congo, Eritrea, Malawi, Mauritius, and the Seychelles). The average number of ICU beds needed at outbreak peak across the 52 included countries ranged from 2 per 100,000 people (SD: 0.1) when 30% of people with severe COVID-19 infections access health services to 6.5 per 100,000 (SD: 0.5) assuming 100% of people seek out health services.
    keywords: beds; countries; covid-19; health; peak; services
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        item: #5588 of 7819
          id: cord-326709-zr3ju2rz
      author: Allali, Gilles
       title: Dyspnea: the vanished warning symptom of COVID‐19 pneumonia
        date: 2020-06-12
       words: 274
      flesch: 36
     summary: All rights reserved The neuro-invasiveness-related vanishing dyspnea hypothesis illustrates this dichotomy of having severe hypoxemia without dyspnea and may explain the high mortality in COVID-19 patients admitted (too late) in the ICU. Yet, dyspnea has been strongly associated with a poor prognosis in the general population, in patients with chronic obstructive pulmonary disease, and also in patients surviving acute hypercapnic respiratory failure.
    keywords: dyspnea
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        item: #5589 of 7819
          id: cord-326717-sebzbijm
      author: Quereshy, Humzah A.
       title: “Hot zones” for otolaryngologists: Assessing the geographic distribution of aerosol-generating procedures amidst the COVID-19 pandemic
        date: 2020-05-27
       words: 2008
      flesch: 33
     summary: As the focus shifts to resuming elective procedures, these potential “hot zones” need to be evaluated for appropriate risk-based decision-making, such as “reopening strategies” and allocation of resources. Therefore, we sought to geographically characterize the predicted burden of aerosolgenerating otolaryngology procedures based on previously reported procedural volumes to predict areas of high-risk to otolaryngologists as recovery plans are implemented and elective procedures resume in the near future.
    keywords: aerosol; covid-19; generating; pandemic; procedures; risk
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        item: #5590 of 7819
          id: cord-326718-jboiufoq
      author: Deming, Meagan E.
       title: COVID-19 and Lessons to Be Learned from Prior Coronavirus Outbreaks
        date: 2020-07-17
       words: 2549
      flesch: 33
     summary: Both strategies result in a lower R 0 and significant decline in COVID-19 cases. 326718 cord_uid: jboiufoq nan A novel coronavirus (CoV) was quickly recognized as the cause of a cluster of severe pneumonia cases in China around December 2019.
    keywords: angiotensin; coronavirus; cov; cov-2; covid-19; enzyme; sars
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        item: #5591 of 7819
          id: cord-326744-eled2tgo
      author: Millett, Gregorio A.
       title: White Counties Stand Apart: The Primacy of Residential Segregation in COVID-19 and HIV Diagnoses
        date: 2020-10-01
       words: 3232
      flesch: 47
     summary: Attributing racial disparities to underlying conditions implicitly blames communities of color for COVID-19 disparities due to poor health decisions; but there is ample literature showing how social determinants contribute to worse health outcomes in communities of color, 29 including well-cited HIV research studies of youth, gay men, and PWID, which show that HIV disparities persist in black communities despite similar or fewer behavioral risks than whites. Many point to underlying health conditions (e.g., obesity, hypertension, diabetes, heart disease) as the source of COVID-19 racial disparities.
    keywords: black; counties; covid-19; disparities; health; hiv; states; white
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        item: #5592 of 7819
          id: cord-326752-45ckkv01
      author: Barnett, Brian
       title: Keeping the wolf at bay: Infection prevention and control measures for inpatient psychiatric facilities in the time of COVID-19
        date: 2020-07-12
       words: 1250
      flesch: 29
     summary: Due to cognitive limitations and severe mental illness, many patients also struggle with attending to activities of daily living, such as bathing and hand hygiene [11, 12] . Patients are frequently admitted to psychiatric facilities directly from areas at high risk for COVID-19 dissemination, such as hospitals, correctional facilities, nursing homes, emergency rooms and homeless shelters.
    keywords: covid-19; patients
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        item: #5593 of 7819
          id: cord-326798-5j8otrzs
      author: Guisado-Vasco, Pablo
       title: COVID-19 and metabolic syndrome: NF-kB activation. Crossroads
        date: 2020-08-28
       words: 523
      flesch: 32
     summary: Emerging data suggest that diabetes mellitus and obesity (BMI > 30) are common risk factors in COVID-19 patients, with a high prevalence rate that reaches nearly 21% As other members of its group, SARS-CoV2 is able to cause a severe acute respiratory syndrome (named COVID-19 disease).
    keywords: covid-19; disease; patients
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        item: #5594 of 7819
          id: cord-326805-c5co9cfq
      author: Lin, Shi-hui
       title: Coronavirus Disease 2019 (COVID-19): Cytokine Storms, Hyper-Inflammatory Phenotypes, and Acute Respiratory Distress Syndrome
        date: 2020-06-29
       words: 1366
      flesch: 33
     summary: [42] Subphenotypes 35 with higher Ang-2 levels, which are characterized by higher inflammatory biomarkers and 1 hypotension, may reflect more endothelial permeability and predilection for extravascular fluid 2 accumulation that responds favorably to fluid restriction. Finally, we explore the possibility of improving the quality of monitoring and treatment of COVID-19 patients and in reducing the incidence of critical illness and mortality via better distinguishing hyper- and hypo-inflammatory subphenotypes of COVID-19.
    keywords: ards; covid-19; hyper; patients; syndrome
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        item: #5595 of 7819
          id: cord-326820-11sl17ap
      author: Bousquet, Jean
       title: Is diet partly responsible for differences in COVID-19 death rates between and within countries?
        date: 2020-05-27
       words: 2316
      flesch: 47
     summary: These considerations may be partly involved in lower death rates in Southern Italy compared to the Northern part. Among the many possible areas of research, it might be important to understand diet and angiotensin-converting enzyme-2 (ACE2) levels in populations with different COVID-19 death rates since dietary interventions may be of great benefit.
    keywords: ace; angiotensin; countries; covid-19; death; differences; rates
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        item: #5596 of 7819
          id: cord-326821-x6comwwl
      author: Castelli, Roberto
       title: Abnormal Hemostatic Parameters and Risk of Thromboembolism Among Patients With COVID-19 Infection
        date: 2020-04-23
       words: 903
      flesch: 30
     summary: The hypothesis of improving the clinical outcome of COVID-19 patients by simple and inexpensive antithrombotic drugs is very appealing, but several issues need to be addressed and clarified before adopting an aggressive approach, in particular defining the appropriate timing for the start of the treatment and the dosage, which may impact concomitant medications. While the scientific community is waiting for more robust evidence on the role of heparin or antiplatelet therapy in coagulopathies associated with COVID-19 infection, the Italian Society on Thrombosis and Hemostasis suggests some recommendations [12] , based on expert consensus, for the management of the hemostasis derangement in COVID-19 patients (Figs. 1-3) .
    keywords: coronavirus; covid-19; patients
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        item: #5597 of 7819
          id: cord-326831-dvg0isgt
      author: Muhammad, L. J.
       title: Predictive Data Mining Models for Novel Coronavirus (COVID-19) Infected Patients’ Recovery
        date: 2020-06-21
       words: 2717
      flesch: 44
     summary: In this study, data mining models were developed for the prediction of COVID-19 infected patients’ recovery using epidemiological dataset of COVID-19 patients of South Korea. Data mining models are evaluated using evaluation techniques to determine their accuracy
    keywords: covid-19; data; dataset; mining; models; pandemic; patients
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        item: #5598 of 7819
          id: cord-326834-eeldyj2u
      author: Graziani, Desirée
       title: Characteristics and Prognosis of COVID-19 in Patients with COPD
        date: 2020-10-12
       words: 4371
      flesch: 40
     summary: The demographic and clinical characteristics of COVID-19 patients with and without COPD are shown in Table 1 . The demographic and clinical characteristics of COVID-19 patients with and without COPD are shown in Table 1 .
    keywords: copd; covid-19; data; disease; mortality; patients; population; study
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        item: #5599 of 7819
          id: cord-326839-nhzasi5a
      author: Ferreli, Fabio
       title: Clinical presentation at the onset of COVID-19 and Allergic Rhinoconjunctivitis
        date: 2020-08-18
       words: 505
      flesch: 44
     summary: investigated to test the hypothesis that patients with a diagnosis of ARC seem to be more 118 affected by olfactory dysfunction when contracting COVID-19, as raised by some authors. In our experience, no differences in taste and smell dysfunction were reported among 120 COVID-19 patients with or without a diagnosis of ARC.
    keywords: covid-19; patients
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        item: #5600 of 7819
          id: cord-326843-ehw4x5vv
      author: Sellal, François
       title: Manifestations neurologiques dans la pandémie de Covid-19
        date: 2020-08-14
       words: 2535
      flesch: 52
     summary: Leur physiopathogénie pourrait relever d'une perturbation des phénomènes de coagulation, du fait du syndrome inflammatoire, mais aussi d'un état d'hypercoagulabilité propre à la Covid-19, dont témoignent des taux plus élevés de D-dimères, comme ceci avait déjà été rapporté dans le MERS L’anosmie, qui est très fréquente est le plus souvent due à une atteinte de l’épithélium olfactif mais peut être due à une extension de l’agression virale au nerf et au cortex olfactifs.
    keywords: cas; covid-19; dans; des; les; neurologiques; qui; syndrome; une
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        item: #5601 of 7819
          id: cord-326849-vqpwdlj7
      author: Rao US, Vishal
       title: Mesenchymal Stem Cells -Bridge Catalyst Between Innte And Adaptive Immunity In Covid 19
        date: 2020-05-18
       words: 1829
      flesch: 42
     summary: Mesenchymal stem cells are known to suppress overactive immune responses as well as bring about tissue regeneration and repair. Mesenchymal stem cells are known to suppress overactive immune responses as well as bring about tissue regeneration and repair.
    keywords: cells; covid; mesenchymal; patients; responses
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        item: #5602 of 7819
          id: cord-326851-0jxdnm1l
      author: Lee, Sang M.
       title: Lessons Learned from Battling COVID-19: The Korean Experience
        date: 2020-10-16
       words: 9670
      flesch: 46
     summary: This study attempts to present directions for potential changes in the crisis response systems of public healthcare worldwide, by analyzing COVID-19 pandemic response cases, both successes and failures, in Korea. On 10 March 2020, the Korean government established residential treatment centers to treat confirmed COVID-19 patients while maintaining their quarantine.
    keywords: cases; covid-19; covid-19 pandemic; crisis; daegu; government; healthcare; hospital; infection; korea; pandemic; patients; people; public; response; spread; system; virus
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        item: #5603 of 7819
          id: cord-326852-gm98s8a3
      author: Teo, Wan-Yee
       title: Implications for Border Containment Strategies when COVID-19 Presents Atypically
        date: 2020-07-24
       words: 1966
      flesch: 49
     summary: The events leading up to his COVID-19 diagnosis highlight the gaps of the international screening processes at the global border entry, and the potential consequences of community chain transmission through imported COVID-19 cases. The events leading up to his COVID-19 diagnosis highlight the gaps of the international screening processes at the global border entry, and the potential consequences of community chain transmission through imported COVID-19 cases.
    keywords: border; covid-19; patient; symptoms; throat
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        item: #5604 of 7819
          id: cord-326853-miyvn7vd
      author: Chien, Lung-Chang
       title: Meteorological impacts on the incidence of COVID-19 in the U.S.
        date: 2020-07-04
       words: 2644
      flesch: 36
     summary: Figure 1 shows that the percentage change of relative risk (RR %) of COVID-19 incidence had diverse variations among different meteorological factors. Finally, according to the smallest AIC in temperature and relative humidity measures, the average temperature and minimum relative humidity were selected to fit with precipitation in Model 3 to investigate the compound influence on COVID-19 incidence.
    keywords: covid-19; humidity; precipitation; relative; temperature
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        item: #5605 of 7819
          id: cord-326864-i1r3bv4p
      author: Hon, Kam Lun
       title: Coronavirus disease 2019 (COVID-19): latest developments in potential treatments
        date: 2020-06-29
       words: 6276
      flesch: 37
     summary: A pneumonia outbreak associated with a new coronavirus of probable bat origin Clinical features of patients infected with 2019 novel coronavirus in Wuhan Pathological findings of COVID-19 associated with acute respiratory distress syndrome The clinical pathology of severe acute respiratory syndrome (SARS): a report from China Clinicopathologic, immunohistochemical, and ultrastructural findings of a fatal case of middle east respiratory syndrome coronavirus infection in the United Arab Emirates Severe acute respiratory syndrome vs. The Middle East respiratory syndrome Severe acute respiratory syndrome: SARS or not SARS Typical or atypical pneumonia and severe acute respiratory symptoms in PICU Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission Q&A: similarities and differences -COVID-19 and influenza Report of the WHO-China Joint Mission on Coronavirus Disease Solidarity clinical trial for COVID-19 treatments A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version) Intensive care management of coronavirus disease 2019 (COVID-19 ): challenges and recommendations Compassionate use of remdesivir for patients with severe covid-19 COVID-19 treatment: a review of early and emerging options Remdesivir as a possible therapeutic option for the COVID-19 Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial NIH clinical trial shows remdesivir accelerates recovery from advanced COVID-19 Gilead announces results from phase 3 trial of investigational antiviral remdesivir in patients with severe COVID-19 Study to evaluate the safety and antiviral activity of remdesivir (GS-5734 TM ) in participants with moderate coronavirus disease (COVID-19) compared to standard of care treatment Study to evaluate the safety and antiviral activity of remdesivir (GS-5734 TM ) in participants with severe coronavirus disease (COVID-19 Adaptive COVID-19 treatment trial Multi-centre, adaptive, randomized trial of the safety and efficacy of treatments of COVID-19 in hospitalized adults A trial of lopinavir-ritonavir in adults hospitalized with severe covid-19 Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro Lopinavir/ritonavir, ribavirin and IFN-beta combination for nCoV treatment Multicenter clinical study on the efficacy and safety of Xiyanping injection in the treatment of new coronavirus infection pneumonia (General and Severe An investigation into beneficial effects of interferon beta 1a, compared to interferon beta 1b and the base therapeutic regiment in moderate to severe COVID-19: a randomized clinical trial (DIC) Treatment of severe acute respiratory syndrome with lopinavir/ritonavir: a multicentre retrospective matched cohort study Treatment of Middle East Respiratory Syndrome with a combination of lopinavir-ritonavir and interferon-β1b (MIRACLE trial): study protocol for a randomized controlled trial Novel coronavirus treatment with ribavirin: groundwork for an evaluation concerning COVID-19 SARS: systematic review of treatment effects Clinical features and short-term outcomes of 144 patients with SARS in the Greater Toronto area Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirin National Health Commission & State Administration of Traditional Chinese Medicine. [34] [35] Therapeutics for COVID-19 The majority of COVID-19 patients, especially children, are either asymptomatic or have mild symptoms, and will likely recover by managing their own symptoms without the need for hospitalisation.
    keywords: clinical; coronavirus; cov-2; covid-19; disease; lopinavir; mers; patients; ritonavir; sars; syndrome; treatment; trial; use
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        item: #5606 of 7819
          id: cord-326866-nbd4arhx
      author: Fox, Charles W.
       title: The representation of women as authors of submissions to ecology journals during the COVID-19 pandemic
        date: 2020-05-29
       words: 1948
      flesch: 42
     summary: key: cord-326866-nbd4arhx authors: Fox, Charles W. title: The representation of women as authors of submissions to ecology journals during the COVID-19 pandemic date: 2020-05-29 journal: bioRxiv DOI: 10.1101/2020.05.29.123455 sha: doc_id: 326866 cord_uid: nbd4arhx Observations made from papers submitted to preprint servers, and the speculation of editors on social media platforms, suggest that women are submitting fewer papers to scholarly journals than are men during the COVID-19 pandemic. Women were similarly represented among submitting authors (the person who submitted the manuscript to ScholarOne Manuscripts); 39.1% of submitting authors were women (averaged across journals), though this varied among journals from a high of 51.2% to a low of 30.4% ( Figure 1B ).
    keywords: covid; journals; submissions; women
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        item: #5607 of 7819
          id: cord-326874-rdwvsm4s
      author: Wu, Chaomin
       title: Corticosteroid therapy for coronavirus disease 2019-related acute respiratory distress syndrome: a cohort study with propensity score analysis
        date: 2020-11-10
       words: 4472
      flesch: 31
     summary: In this clinical practice setting, low-dose corticosteroid treatment was associated with reduced risk of in-hospital death within 60 days in COVID-19 patients who developed ARDS. [7] , and has been widely used by clinicians to suppression of hyperinflammation in COVID-19 patients, especially those with critical illness
    keywords: ards; corticosteroids; covid-19; days; hospital; patients; score; treatment
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        item: #5608 of 7819
          id: cord-326881-3j2e92dj
      author: Vassallo, M.
       title: Patients with Covid-19 exhibit different immunological profiles according to their clinical presentation
        date: 2020-09-28
       words: 2388
      flesch: 36
     summary: Conclusions In a population of elderly patients recently infected with Covid-19, CD10 + B cell levels were inversely correlated with clinical severity. Qin et al. found lower levels of helper T cells and suppressor T cells in severe patients, but demographic characteristics of severe and non-severe patients were significantly different
    keywords: cells; coronavirus; covid-19; infection; patients
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        item: #5609 of 7819
          id: cord-326903-t2cx2ju5
      author: Zhou, J.
       title: Altered blood cell traits underlie a major genetic locus of severe COVID-19
        date: 2020-09-10
       words: 3446
      flesch: 44
     summary: These results suggest a possibility that the target gene of the COVID-19 risk variant is involved in hematologic processes and regulates blood cell counts. On the other hand, the vast majority of existing studies measured blood cell counts at hospital admission or during hospitalization, which likely reflect immune responses to SARS-CoV-2 infection.
    keywords: blood; covid-19; license; medrxiv; perpetuity; preprint; risk
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        item: #5610 of 7819
          id: cord-326916-bakwk4tm
      author: Fauver, Joseph R.
       title: Coast-to-Coast Spread of SARS-CoV-2 during the Early Epidemic in the United States
        date: 2020-05-07
       words: 5565
      flesch: 43
     summary: To delineate the roles of domestic and international virus spread in the emergence of new United States COVID-19 outbreaks, we sequenced SARS-CoV-2 viruses collected from cases identified in Connecticut. By March 18, the five countries comprised 78% of reported non-United States cases, whereas the five states comprised 48% of reported domestic cases outside of Connecticut and New York.
    keywords: cases; connecticut; cov-2; covid-19; data; international; new; number; sars; states; travel; united
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        item: #5611 of 7819
          id: cord-326945-fvgc33qx
      author: Babapoor-Farrokhran, Savalan
       title: Cardiac Arrhythmias in the Era of COVID-19 Pandemic
        date: 2020-09-11
       words: 777
      flesch: 30
     summary: They further touch upon treatment, management, and monitoring strategies for COVID-19 patients. According to one survey, atrial fibrillation (AF) was the most commonly encountered cardiac arrhythmia in COVID-19 patients [6] .
    keywords: cardiac; covid-19; patients
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        item: #5612 of 7819
          id: cord-326956-oz047qmf
      author: Lu, Yiping
       title: Cerebral Micro-Structural Changes in COVID-19 Patients – An MRI-based 3-month Follow-up Study
        date: 2020-08-03
       words: 5829
      flesch: 43
     summary: COVID-19 patients had statistically significantly higher bilateral gray matter volumes (GMV) in olfactory cortices, hippocampi, insulas, left Rolandic operculum, left Heschl's gyrus and right cingulate gyrus and a general decline of MD, AD, RD accompanied with an increase of FA in white matter, especially AD in the right CR, EC and SFF, and MD in SFF compared with non-COVID-19 volunteers (corrected p value <0.05). No data has been reported about the structural changes in the brain from COVID-19 patients by functional MRI in a prospective way.
    keywords: cingulate; cov-2; covid-19; gmv; gyrus; olfactory; patients; right; sars; value
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        item: #5613 of 7819
          id: cord-326961-ti6mrzxf
      author: Aly, Mariam Mohsen
       title: Impact of novel coronavirus disease (COVID-19) on Egyptian dentists’ fear and dental practice (a cross-sectional survey)
        date: 2020-10-12
       words: 2887
      flesch: 40
     summary: An online survey was submitted to dental professionals. COVID-19 pandemic has a significant impact on dental professionals.
    keywords: covid-19; dental; dentists; fear; infection; study
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        item: #5614 of 7819
          id: cord-326969-4f9djufi
      author: Stein, Richard A.
       title: When Public Health Crises Collide: Social Disparities and COVID‐19
        date: 2020-05-14
       words: 1833
      flesch: 36
     summary: Results from the Boston Area Community Health (BACH) survey Racial and Ethnic Disparities in Prevalence and Care of Patients With Type 2 Diabetes Diabetes health disparities: a systematic review of health care interventions Disparities in diabetes management practice between racial and ethnic groups in the United States Blood pressure control in diabetes: temporal progress yet persistent racial disparities: national results from the REasons for Geographic And Racial Differences in Stroke (REGARDS) study Beyond Access: All rights reserved 16 Unraveling common threads in obesity risk among racial/ethnic minority and migrant populations Analysis Grid for Environments Linked to Obesity (ANGELO) framework to develop community-driven health programmes in an Indigenous community in Canada Practical Research Strategies for Reducing Social and Racial/Ethnic Disparities in Obesity Obesity and overweight in ethnic minorities of the Detroit metropolitan area of Michigan Racial and ethnic disparities in diabetes complications in the northeastern United States: the role of socioeconomic status Inequality in the built environment underlies key health disparities in physical activity and obesity
    keywords: covid-19; disparities; groups; health; obesity; risk
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        item: #5615 of 7819
          id: cord-326971-jekqhslx
      author: Schnepper, Rebekka
       title: Being My Own Companion in Times of Social Isolation – A 14-Day Mobile Self-Compassion Intervention Improves Stress Levels and Eating Behavior
        date: 2020-10-09
       words: 4969
      flesch: 45
     summary: The intervention consisted of daily journaling exercises and meditations via smartphone with a focus on improving eating behavior. The PROCESS 3.5 macro for SPSS (Hayes, 2013) was used to build a mediation model with groups as a predictor for change scores of stress, BMI, and eating behavior, and the SC change score as a mediator.
    keywords: compassion; eating; intervention; lockdown; participants; self
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        item: #5616 of 7819
          id: cord-326989-l8nfd03a
      author: Cammarota, Gianmaria
       title: Critical Care Surge Capacity to Respond to the COVID-19 Pandemic in Italy: A Rapid and Affordable Solution in the Novara Hospital
        date: 2020-05-19
       words: 1312
      flesch: 35
     summary: However, being that the operating rooms converted into COVID-19 ICU stations, which were dispersed in different locations distant from the supervision of the control unit, the ICU staff had significant difficulties to work as one team and to ensure the same level of care. By addressing the key elements of health care system surge capacity from contingency to crisis, a prompt response to the sudden request of IMV was provided, converting the general ICU into a COVID-19 unit and increasing the number of COVID-19 ICU beds by 107%.
    keywords: care; covid-19; icu; unit
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        item: #5617 of 7819
          id: cord-326991-m0lfk0a9
      author: Nuñez, Jorge H.
       title: Rethinking Trauma Hospital Services in one of Spain's Largest University Hospitals during the COVID-19 pandemic. How can we organize and help? Our experience.
        date: 2020-09-25
       words: 4020
      flesch: 52
     summary: Daily telematics-obtained information on the status of COVID-19 positive patients is vital. At the beginning of the first week, healthcare personnel only used surgical masks in the hospital, and we only tested emergency room patients who reported symptoms.
    keywords: covid-19; emergency; healthcare; hospital; pandemic; patients; surgeries; trauma
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        item: #5618 of 7819
          id: cord-326996-va073yuz
      author: Sang, Ling
       title: The incidence, risk factors and prognosis of acute kidney injury in severe and critically ill patients with COVID-19 in mainland China: a retrospective study
        date: 2020-11-09
       words: 3558
      flesch: 45
     summary: key: cord-326996-va073yuz authors: Sang, Ling; Chen, Sibei; Zheng, Xia; Guan, Weijie; Zhang, Zhihui; Liang, Wenhua; Zhong, Ming; Jiang, Li; Pan, Chun; Zhang, Wei; Xia, Jiaan; Chen, Nanshan; Wu, Wenjuan; Wu, Hongkai; Xu, Yonghao; Liu, Xuesong; Liu, Xiaoqing; He, Jianxing; Li, Shiyue; Zhang, Dingyu; Zhong, Nanshan; Li, Yimin title: The incidence, risk factors and prognosis of acute kidney injury in severe and critically ill patients with COVID-19 in mainland China: a retrospective study date: 2020-11-09 journal: BMC Pulm Med DOI: 10.1186/s12890-020-01305-5 sha: doc_id: 326996 cord_uid: va073yuz BACKGROUND: The clinical correlates, prognosis and determinants of acute kidney injury (AKI) in patients with coronavirus disease 2019 (Covid-19) remain largely unclear. Of 92 (43.8%) patients who developed AKI during hospitalization, 13 (14.1%), 15 (16.3%) and 64 (69.6%) were classified as being at stage 1, 2 and 3, respectively.
    keywords: acute; aki; clinical; covid-19; kidney; patients; risk; study
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        item: #5619 of 7819
          id: cord-327003-2z0ftel0
      author: Makurumidze, Richard
       title: Coronavirus-19 Disease (COVID-19): A case series of early suspects reported and the implications towards the response to the pandemic in Zimbabwe
        date: 2020-04-13
       words: 863
      flesch: 51
     summary: Despite the 22 associated high risk, the number of reported cases has been rising slower than anticipated 23 considering their weak health and emergency preparedness and response systems 2 . The country might not be screening optimally, considering the number of COVID-19 tests conducted to date and suspected cases who missed testing.
    keywords: cases; coronavirus; covid-19
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        item: #5620 of 7819
          id: cord-327006-m847xdzk
      author: Di Castelnuovo, A.
       title: Low dose hydroxychloroquine is associated with lower mortality in COVID-19: a meta-analysis of 26 studies and 44,521 patients
        date: 2020-11-04
       words: 4806
      flesch: 43
     summary: The association was apparent by pooling 22 observational studies and was more evident in studies which used lower HCQ doses. Obviously these three conditions largely overlapped in studies, that we can now designate as at low HCQ dose.
    keywords: covid-19; hcq; license; medrxiv preprint; mortality; preprint; review; studies
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        item: #5621 of 7819
          id: cord-327017-b2refzfw
      author: Elbeddini, Ali
       title: Pharmacist intervention amid the coronavirus disease 2019 (COVID-19) pandemic: from direct patient care to telemedicine
        date: 2020-05-27
       words: 1627
      flesch: 45
     summary: key: cord-327017-b2refzfw authors: Elbeddini, Ali; Yeats, Aniko title: Pharmacist intervention amid the coronavirus disease 2019 (COVID-19) pandemic: from direct patient care to telemedicine date: 2020-05-27 journal: J Pharm Policy Pract DOI: 10.1186/s40545-020-00229-z sha: doc_id: 327017 cord_uid: b2refzfw The coronavirus disease (COVID-19) pandemic has placed enormous pressures on the Canadian healthcare system. Fortunately, many pharmacy services can be delivered over the phone, but the question arises about whether the quality of care by virtual means is on par with that of direct patient care.
    keywords: care; covid-19; pandemic; patients
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        item: #5622 of 7819
          id: cord-327028-dbvucvy3
      author: Zhang, Cantong
       title: Controversial treatments: An updated understanding of the coronavirus disease 2019
        date: 2020-04-10
       words: 1905
      flesch: 25
     summary: mBio Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys Treating Ebola virus infection Mechanism of inhibition of Ebola virus RNA-dependent RNA polymerase by remdesivir First case of 2019 novel coronavirus in the United States A randomized, controlled trial of Ebola virus disease therapeutics Severe 2019-nCoV Remdesivir RCT Mild/Moderate 2019-nCoV Remdesivir RCT In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings Ribavirin and interferon-β synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus Severe acute respiratory syndromerelated coronavirus is inhibited by interferon-α SARS: systematic review of treatment effects Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area Common adverse events associated with the use of ribavirin for severe acute respiratory syndrome in Canada Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area Severe acute respiratory syndrome: report of treatment and outcome after a major outbreak Pre-emptive use of aerosolized ribavirin in the treatment of asymptomatic pediatric marrow transplant patients testing positive for RSV Chinese Clinical Guidance. Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Multicenter collaboration group of Department of Science and Technology of Guangdong Province and Health Commission of Guangdong Province for chloroquine in the treatment of novel coronavirus pneumonia.
    keywords: coronavirus; novel; patients; remdesivir; sars; treatment
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        item: #5623 of 7819
          id: cord-327032-4bet4e8l
      author: Khan, S. H.
       title: Delirium Incidence, Duration and Severity in Critically Ill Patients with COVID-19
        date: 2020-06-01
       words: 3705
      flesch: 40
     summary: 26, 27 Our study findings represent a significant departure from recently reported trends in rates of ICU delirium, including rates of mechanical ventilation (36%), delirium (22.7%), and coma (24.0%) at our own center during the influenza pandemic occurring in 2009-2010 (see Supplementary Table 2 ). Reductions in the prevalence of ICU delirium from a historical high of 80% to rates of 16.5-33% have been reported over the past two years.
    keywords: cam; covid-19; delirium; icu; license; patients; preprint
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        item: #5624 of 7819
          id: cord-327058-7cnuem33
      author: Wong, Anna S. Y.
       title: Social capital and public health: responding to the COVID-19 pandemic
        date: 2020-09-25
       words: 2265
      flesch: 26
     summary: Social capital, social theory, and the political economy of public health Social capital and health in the least developed countries: a critical review of the literature and implications for a future research agenda Social capital in the creation of human capital COVID-19 growth rate decreases with social capital COVID-19 and mental health: a review of the existing literature Mental health and the Covid-19 pandemic The emotional path to action: Empathy promotes physical distancing and wearing face masks during the COVID-19 pandemic COVID-19: universal health coverage now more than ever Undocumented U.S. Immigrants and Covid-19 Caring for the unseen: using linking social capital to improve healthcare access to irregular migrants in Spain Tessa Senneker and Doret Cheng are acknowledged for their prior background research which helped inform this commentary. key: cord-327058-7cnuem33 authors: Wong, Anna S. Y.; Kohler, Jillian C. title: Social capital and public health: responding to the COVID-19 pandemic date: 2020-09-25 journal: Global Health DOI: 10.1186/s12992-020-00615-x sha: doc_id: 327058 cord_uid: 7cnuem33 BACKGROUND: As countries continue to respond to the COVID-19 pandemic, the importance of ensuring that fair and equal access to healthcare for all is more urgent than ever.
    keywords: capital; covid-19; health; public; response
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        item: #5625 of 7819
          id: cord-327063-ea7a1xfl
      author: Dhama, Kuldeep
       title: SARS-CoV-2 jumping the species barrier: zoonotic lessons from SARS, MERS and recent advances to combat this pandemic virus
        date: 2020-08-02
       words: 11075
      flesch: 42
     summary: CORONAVIRUS DISEASE 2019 UPDATE (22): COMPANION ANIMAL, DOG SUSPECTED, REQUEST FOR INFORMATION Infection of dogs with SARS-CoV-2 Coronavirus can infect cats -dogs, not so much First detection and genome sequencing of SARS-CoV-2 in an infected cat in France Virology: SARS virus infection of cats and ferrets Belgian cat infected by owner. key: cord-327063-ea7a1xfl authors: Dhama, Kuldeep; Patel, Shailesh Kumar; Sharun, Khan; Pathak, Mamta; Tiwari, Ruchi; Yatoo, Mohd Iqbal; Malik, Yashpal Singh; Sah, Ranjit; Rabaan, Ali A.; Panwar, Parmod Kumar; Singh, Karam Pal; Michalak, Izabela; Chaicumpa, Wanpen; Martinez-Pulgarin, Dayron F.; Bonilla-Aldana, D. Katterine; Rodriguez-Morales, Alfonso J. title: SARS-CoV-2 jumping the species barrier: zoonotic lessons from SARS, MERS and recent advances to combat this pandemic virus date: 2020-08-02 journal:
    keywords: animal; bats; cases; coronavirus; cov-2; covid-19; covs; disease; health; host; human; infection; mers; novel; pandemic; patients; pneumonia; receptor; sars; species; spillover; transmission
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        item: #5626 of 7819
          id: cord-327084-r12copka
      author: Zhang, Chenxi
       title: Survey of Insomnia and Related Social Psychological Factors Among Medical Staff Involved in the 2019 Novel Coronavirus Disease Outbreak
        date: 2020-04-14
       words: 4092
      flesch: 45
     summary: Front Psychiatry DOI: 10.3389/fpsyt.2020.00306 sha: doc_id: 327084 cord_uid: r12copka OBJECTIVE: The outbreak of the 2019 novel coronavirus disease (COVID-19) not only caused particularly large public health problems, but also caused great psychological distress, especially for medical staff. We aimed to investigate the prevalence rate of insomnia and to confirm the related social psychological factors among medical staff in hospitals during the COVID-19 outbreak.
    keywords: covid-19; factors; insomnia; outbreak; staff; study; symptoms
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        item: #5627 of 7819
          id: cord-327086-u3l8nr73
      author: Mauvais-Jarvis, Franck
       title: Estradiol, Progesterone, Immunomodulation, and COVID-19 Outcomes
        date: 2020-07-30
       words: 4720
      flesch: 25
     summary: High physiological concentrations of E2 and P4 possibly synergize to mitigate innate immune cells production of proinflammatory cytokines, promote T cells' anti-inflammatory responses and immune tolerance, and stimulate antibody production by B cells (Fig. 1 ). In an attempt to protect the body from SARS-CoV-2, immune cells infiltrate the lungs, causing hyperactivation of monocytes and macrophages, and elevated production of proinflammatory cytokines (eg, interleukin-6
    keywords: cells; covid-19; disease; il-6; immune; inflammatory; production; responses; sars; women
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        item: #5628 of 7819
          id: cord-327106-drwvzw5l
      author: Eyawo, Oghenowede
       title: Rethinking the Central Role of Equity in the Global Governance of Pandemic Response
        date: 2020-08-25
       words: 2623
      flesch: 38
     summary: We maintain that this requires us to rethink how we can strengthen the role equity plays in guiding the global governance of pandemic preparedness and response, and its wider potential impact for global health governance more generally. COVID-19 provides an opportunity to reset the structure, function, and aims of global health governance.
    keywords: covid-19; global; governance; health; pandemic; response
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        item: #5629 of 7819
          id: cord-327148-dzozl70h
      author: Tahmassebi, Ramon
       title: Reflections from London’s Level-1 Major Trauma Centres during the COVID crisis
        date: 2020-06-26
       words: 2477
      flesch: 40
     summary: Predictably, many patients could be willingly postponed or even discharged by telephone, seemingly confirming that traditional practice around out-patient follow-up is outdated and open to modernisation [12] . We describe the impact of this on the provision of major trauma care in a major capital city.
    keywords: care; covid-19; hospital; pandemic; patient; staff; surgery; trauma
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        item: #5630 of 7819
          id: cord-327151-jn1w8h2p
      author: Walker, Kate F
       title: Maternal transmission of SARS‐COV‐2 to the neonate, and possible routes for such transmission: A systematic review and critical analysis
        date: 2020-06-12
       words: 3708
      flesch: 54
     summary: For reported infant infection a critical analysis was performed to evaluate the likelihood of vertical transmission. All rights reserved few infections have been reported in the newborns of COVID-19 positive mothers.
    keywords: covid-19; infant; infection; neonates; reports; women
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        item: #5631 of 7819
          id: cord-327165-vlyfbiem
      author: Montorfano, Lisandro
       title: Colorectal surgery obesity-related morbidity during COVID-19
        date: 2020-07-09
       words: 2362
      flesch: 37
     summary: The disease has rapidly spread around the world and has been acknowledged as an international public health emergency because of a lack of sufficient resources to care for the increasing number of patients with acute respiratory distress syndrome due to COVID-19 One of the most commonly reported complications of Tocilizumab in patients with rheumatologic conditions is the increased risk of lower gastrointestinal perforations.
    keywords: bowel; care; coronavirus; covid-19; patients; perforation; tocilizumab
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        item: #5632 of 7819
          id: cord-327169-sz4ildnd
      author: Mondoni, Michele
       title: Utility and safety of bronchoscopy during SARS-CoV-2 outbreak in Italy: a retrospective, multicenter study
        date: 2020-08-28
       words: 1348
      flesch: 35
     summary: The indications of bronchoscopy were: -diagnosis of SARS-CoV-2 pneumonia in patients with previously negative nasopharyngeal swab (clinical and radiological suspicion of pneumonia); -need for undelayable procedures in COVID-19 patients (e.g., massive hemoptysis, post-obstructive atelectasis). Similar findings were recently described by Torrego et al. in a Spanish cohort of COVID-19 patients who underwent bronchoscopy in ICU
    keywords: bronchoscopy; covid-19; diagnosis; patients; sars
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        item: #5633 of 7819
          id: cord-327181-z7uqmxki
      author: Nodora, Jesse N
       title: The COVID-19 Pandemic: Identifying Adaptive Solutions for Colorectal Cancer Screening in Underserved Communities
        date: 2020-08-11
       words: 4160
      flesch: 40
     summary: The COVID-19 pandemic has caused delays in CRC screening, including among medically underserved populations, such as those receiving care at community health centers (CHCs). CRC screening is a required, reportable quality metric for federally qualified health centers in the uniform data system.
    keywords: cancer; chcs; covid-19; crc; fit; health; pandemic; screening; telehealth
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        item: #5634 of 7819
          id: cord-327214-kcbxyhhh
      author: Eketunde, Adenike O
       title: A Review of Postmortem Findings in Patients With COVID-19
        date: 2020-07-28
       words: 2733
      flesch: 38
     summary: There is a strong association with the hyperinflammatory state, which can be explained by most of the signs and symptoms that are exhibited by COVID-19 patients, including most of the pathological findings. According to Merad and Martin's study, the hyper inflammation in severe COVID-19 patients shared similarities with cytokine release syndromes, including macrophages activation syndrome.
    keywords: coronavirus; covid-19; disease; findings; macrophages; patients; sars
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        item: #5635 of 7819
          id: cord-327219-gj3otwzj
      author: Gale, Robert Peter
       title: Conquest of COVID‐19. Publish it to Death?
        date: 2020-06-01
       words: 724
      flesch: 55
     summary: Readers will not be surprised the four guidelines received a C for Strength of Recommendation (Poor evidence) and a III for Quality of Evidence (Evidence from opinions of respected authorities… without clinical trials data). All rights reserved Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 Era: Recommendations by an International Expert Panel Quality and strength of evidence of the Infectious Diseases Society of America clinical practice guidelines Validity of the Agency for Healthcare Research and Quality clinical practice guidelines: how quickly do guidelines become outdated? Evidence based medicine: what it is and what it isn't What is quality of evidence and why is it important to clinicians? Annals Clinical Decision Making: Weighing Evidence to Inform Clinical Decisions Is there expert consensus on expert consensus? COVID-19, HCT and wine RPG acknowledges support from the National Institute of Health
    keywords: covid-19; evidence
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        item: #5636 of 7819
          id: cord-327232-oavox35v
      author: da Silva, Flaviane Cristine Troglio
       title: Psychological effects caused by the COVID-19 pandemic in health professionals: A systematic review with meta-analysis
        date: 2020-08-06
       words: 2148
      flesch: 50
     summary: key: cord-327232-oavox35v authors: da Silva, Flaviane Cristine Troglio; Neto, Modesto Leite Rolim title: Psychological effects caused by the COVID-19 pandemic in health professionals: A systematic review with meta-analysis date: 2020-08-06 journal: Psychological suffering by health professionals may be associated with the uncertainty of a safe workplace.
    keywords: covid-19; health; professionals
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        item: #5637 of 7819
          id: cord-327242-g3pfc94x
      author: Nepomnyashchiy, Lyudmila
       title: COVID-19: Africa needs unprecedented attention to strengthen community health systems
        date: 2020-07-16
       words: 1608
      flesch: 50
     summary: Community health workers (CHWs) have insufficient personal protective equipment (PPE) to ensure they can continue providing essential care 14 and most countries face severe shortages of health workers. Lessons from Ebola Community health workers during the Ebola outbreak in Guinea, Liberia, and Sierra Leone Community health worker programmes after the 2013-2016 Ebola outbreak COVID19: it ain't over until there's PPE all over Africa: COVID19 exposes healthcare shortfalls Community health workers and pandemic preparedness: current and prospective roles Xi focus: Xi replies to letter from community workers fighting COVID-19 in Wuhan Prioritising the role of community health workers in the COVID-19 response More harm than good?
    keywords: community; covid-19; ebola; health; response
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        item: #5638 of 7819
          id: cord-327246-idmo5ds7
      author: M, Montero-Baladía
       title: Etoposide treatment adjunctive to immunosuppressants for critically ill COVID-19 patients: Etoposide for severe COVID-19 patients
        date: 2020-06-21
       words: 1409
      flesch: 30
     summary: Regarding oxygenation parameters, we observed that many severe COVID-19 patients presented with alarming PaO 2 /FiO 2 ratios (commonly under 150, see Table- 1) that, according to Berlin ARDS criteria, were immediate candidates for orotracheal intubation and mechanical ventilation. The currently ongoing clinical trial NCT04356690, started on May 8, 2020, will likely contribute to evaluate the safety and efficacy of etoposide in COVID-19 patients.
    keywords: avenida; covid-19; etoposide; islas; patients
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        item: #5639 of 7819
          id: cord-327253-gge6wzly
      author: Villa, Simone
       title: Stigma at the time of the COVID-19 pandemic
        date: 2020-08-07
       words: 1376
      flesch: 47
     summary: In Italy, some politicians accused Chinese people of poor hygiene and unhealthy cultural practices, including that of eating live mice. The Guardian Asian Americans report over 650 racist acts over last week, new data says Politician apologizes for saying coronavirus caused by Chinese people eating 'live mice' Italiani untori You Could Lick the Benches': Life for the First Wave of U Immunity passports in the context of COVID-19.
    keywords: covid-19; health; people; stigma
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        item: #5640 of 7819
          id: cord-327257-doygrgrc
      author: Zhu, Jocelyn
       title: Deep transfer learning artificial intelligence accurately stages COVID-19 lung disease severity on portable chest radiographs
        date: 2020-07-28
       words: 3689
      flesch: 48
     summary: Deep-learning convolutional neural network (CNN) was used to predict lung disease severity scores. [12, 13] with an additional regression layer was utilized to predict disease severity scores of CXR on a graded scale.
    keywords: covid-19; cxr; disease; learning; lung; scores; severity; transfer
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        item: #5641 of 7819
          id: cord-327284-j6cg7nf0
      author: Meireles, André Luís Ferreira
       title: Impact of Social Isolation due to the COVID-19 Pandemic in Patients with Pediatric Disorders: Rehabilitation Perspectives From a Developing Country
        date: 2020-08-17
       words: 1479
      flesch: 23
     summary: Can we count on you? Physical rehabilitation using telemedicine State of the Evidence Traffic Lights 2019: systematic review of interventions for preventing and treating children with cerebral palsy Telehealth application on the rehabilitation of children and adolescents Diversity of practices in telerehabilitation for children with disabilities and effective intervention characteristics: results from a systematic review World Health Organization. Among pediatric patients, according to the literature, COVID-19 appears to be less severe than in adults and the elderly, and approximately 90% of pediatric patients are diagnosed with asymptomatic, mild, or moderate disease.
    keywords: children; covid-19; pandemic; patients; rehabilitation
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        item: #5642 of 7819
          id: cord-327301-5eko4htz
      author: Li, Yang
       title: Chest CT imaging characteristics of COVID-19 pneumonia in preschool children: a retrospective study
        date: 2020-05-18
       words: 3400
      flesch: 48
     summary: [22, 23] , which is difficult to distinguish from CT findings of COVID-19 pneumonia. key: cord-327301-5eko4htz authors: Li, Yang; Cao, Jianghui; Zhang, Xiaolong; Liu, Guangzhi; Wu, Xiaxia; Wu, Baolin title: Chest CT imaging characteristics of COVID-19 pneumonia in preschool children: a retrospective study date: 2020-05-18 journal: BMC Pediatr DOI: 10.1186/s12887-020-02140-7 sha: doc_id: 327301 cord_uid: 5eko4htz BACKGROUND: Recently, the World Health Organization has declared the coronavirus disease 2019 (COVID-19) outbreak a public health emergency of international concern.
    keywords: cases; children; coronavirus; covid-19; imaging; patients; pneumonia
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        item: #5643 of 7819
          id: cord-327349-rxb6zfoc
      author: Au, Lewis
       title: Cancer, COVID-19, and antiviral immunity: the CAPTURE study
        date: 2020-09-03
       words: 4534
      flesch: 25
     summary: key: cord-327349-rxb6zfoc authors: Au, Lewis; Boos, Laura Amanda; Swerdlow, Anthony; Byrne, Fiona; Shepherd, Scott T.C.; Fendler, Annika; Turajlic, Samra title: Cancer, COVID-19, and antiviral immunity: the CAPTURE study date: 2020-09-03 journal: Cell DOI: 10.1016/j.cell.2020.09.005 sha: doc_id: 327349 cord_uid: rxb6zfoc The SARS-CoV-2 pandemic has posed a significant challenge for risk evaluation and mitigation amongst cancer patients. Susceptibility to and severity of COVID-19 in cancer patients has not been studied in a prospective and broadly applicable manner.
    keywords: cancer; capture; cov-2; covid-19; immune; infection; outcomes; patients; response; risk; sars; study
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        item: #5644 of 7819
          id: cord-327360-4qpk99x9
      author: Elsawah, Hozaifa Khalil
       title: Hydroxychloroquine for treatment of non‐severe COVID‐19 patients; systematic review and meta‐analysis of controlled clinical trials
        date: 2020-08-18
       words: 3187
      flesch: 42
     summary: Intensive care medicine RECOVERY trial: the UK covid-19 study resetting expectations for clinical trials Meta-analysis of repeated measures study designs Hydroxychloroquine in lupus: emerging evidence supporting multiple beneficial effects Virological and clinical cure in COVID-19 patients treated with hydroxychloroquine: a systematic review and meta-analysis Hydroxychloroquine in patients with COVID-19: Few retrospective observational studies reported some benefits in treating COVID-19 patients, where HCQ decreased mortality and IL-6 level 21 , decreased case fatality rate 22 , and improved patient survival 23 .
    keywords: clinical; covid-19; disease; hcq; hydroxychloroquine; patients; studies; study
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        item: #5645 of 7819
          id: cord-327363-z30zoogs
      author: Neve, D.
       title: On Modeling of COVID-19 for the Indian Subcontinent using Polynomial and Supervised Learning Regression
        date: 2020-10-16
       words: 4312
      flesch: 58
     summary: India currently has the largest number of confirmed cases in Asia, [5] and has the second-highest number of confirmed cases in the world after the United States, [6] [7] with the number of total confirmed cases breaching the 100,000 mark on 19 May, [8] and 1,000,000 confirmed cases on 17 July 2020. On 29 August 2020, India recorded the global highest single-day spike in COVID-19 cases with 78,761 cases, surpassing the previous record of 77,368 cases recorded in the US on 17 July 2020.
    keywords: cases; covid-19; data; medrxiv; polynomial; preprint; regression; total
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        item: #5646 of 7819
          id: cord-327370-zo0n8wf6
      author: Vadukul, Prakash
       title: Massive pulmonary embolism following recovery from COVID-19 infection: inflammation, thrombosis and the role of extended thromboprophylaxis
        date: 2020-09-13
       words: 3120
      flesch: 34
     summary: COVID-19 infection: origin, transmission, and characteristics of human coronaviruses Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Facing COVID-19 in the ICU: vascular dysfunction, thrombosis, and dysregulated inflammation Blood coagulation in immunothrombosis-At the frontline of intravascular immunity Coagulation abnormalities and thrombosis in patients with COVID-19 Interleukin 6 and haemostasis Interleukin 6 regulates psoriasiform inflammationassociated thrombosis Interleukin-6 in COVID-19: a systematic review and metaanalysis SARS-CoV-2 and COVID-19: Is interleukin-6 (IL-6) the 'culprit lesion' of ARDS onset? key: cord-327370-zo0n8wf6 authors: Vadukul, Prakash; Sharma, Deepak S; Vincent, Paul title: Massive pulmonary embolism following recovery from COVID-19 infection: inflammation, thrombosis and the role of extended thromboprophylaxis date: 2020-09-13 journal: BMJ Case Rep DOI: 10.1136/bcr-2020-238168 sha: doc_id: 327370 cord_uid: zo0n8wf6 COVID-19 is the infectious disease caused by a recently discovered SARS-CoV-2.
    keywords: care; covid-19; disease; infection; patients; risk; thrombosis; vte
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        item: #5647 of 7819
          id: cord-327388-26ot3cuy
      author: Lu, Amy
       title: The Tipping Point of Medical Technology: Implications for the Postpandemic Era
        date: 2020-06-16
       words: 2351
      flesch: 24
     summary: key: cord-327388-26ot3cuy authors: Lu, Amy; Cannesson, Maxime; Kamdar, Nirav title: The Tipping Point of Medical Technology: Implications for the Postpandemic Era date: 2020-06-16 journal: Anesth Analg DOI: 10.1213/ane.0000000000005040 sha: doc_id: 327388 cord_uid: 26ot3cuy nan T he unprecedented challenges of Coronavirus Disease 2019 (COVID-19) have pushed the limits of medicine and health care over the tipping point of what we thought imaginable, forcing solutions to problems that previously mired rapid progress. Whereas classic infectioncontrol and public health measures were used during the severe acute respiratory syndrome (SARS) epidemic in 2003, COVID-19 provides the opportunity to explore the potential of new digital technologies, including big data analytics, artificial intelligence, blockchain technology, and the Internet of Things.
    keywords: care; covid-19; data; health; pandemic; patients; technology; telehealth
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        item: #5648 of 7819
          id: cord-327394-mwbmi88i
      author: Edwards, Jodi-Ann
       title: Lessons Learned at a COVID-19 designated hospital
        date: 2020-08-04
       words: 914
      flesch: 46
     summary: They ensured resident safety, continued surgical education, participation and contribution to the care of COVID-19 patients. The Department of Surgery implemented drastic changes to address the hospital's needs while remaining committed to the education of surgical residents.
    keywords: covid-19; emergency; patients; residents
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        item: #5649 of 7819
          id: cord-327397-8rxjju0t
      author: Zhang, H.-Y.
       title: A Multicentre Study of 2019 Novel Coronavirus Disease Outcomes of Cancer Patients in Wuhan, China
        date: 2020-03-26
       words: 3507
      flesch: 53
     summary: In this multicentre retrospective study, we reported the largest cohort of cancer patients with of COVID-19 patients develop ARDS, 7 while the incidence rate of ARDS in our cancer cohort was 16.42%. Two previous case series from China have suggested that cancer patients are at a higher risk of COVID-19 pneumonia, but the reports were limited by small numbers and few clinical information.
    keywords: cancer; covid-19; license; patients; preprint; treatment
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        item: #5650 of 7819
          id: cord-327403-adwj2xq7
      author: Speth, Marlene M.
       title: Mood, anxiety and olfactory dysfunction in COVID‐19: evidence of central nervous system involvement?
        date: 2020-07-02
       words: 3451
      flesch: 47
     summary: Specifically, we focused on the severity of COVID-19 symptoms-as reflections of ongoing COVID-19 pathophysiology-as risk factors for greater burdens of depressed mood and anxiety. We found that depressed mood and anxiety were positively associated with COVID-19 symptoms of decreased sense of smell and taste.
    keywords: anxiety; covid-19; patients; score; smell; study; symptoms
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        item: #5651 of 7819
          id: cord-327413-zdbnoy1q
      author: Bendjelid, Karim
       title: Hemodynamic monitoring of Covid-19 patients. Classical methods and new paradigms
        date: 2020-09-04
       words: 1314
      flesch: 31
     summary: Interestingly, when analysing the data, the authors found that the majority of COVID-19 ICU patients required vasopressor support, with certain changes in cardiac function patterns warranting echocardiographic monitoring. Indeed, the key information to know regarding vasopressor requirements in COVID-19 ICU patients is the mean dose used.
    keywords: care; covid-19; monitoring; patients
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        item: #5652 of 7819
          id: cord-327415-nu1msnui
      author: Kadiane-Oussou, N’dri Juliette
       title: COVID-19: comparative clinical features and outcome in 114 patients with or without pneumonia (Nord Franche-Comte Hospital, France)
        date: 2020-10-10
       words: 1732
      flesch: 51
     summary: In a recent published 140 article, we suggested that neurologic symptoms in COVID-19 were more frequently described in Patients with COVID-19 pneumonia are usually hospitalized for observation and supportive care (13) 154 (in our study, 95% of patients in group P were hospitalized). Patients with 156 COVID-19 pneumonia may become critically ill; more than a fifth of patients in group P were 157 transferred to ICU for ARDS with a mean duration of hospitalization in ICU of 12 days and a high 158 lethality as compared to the mortality described in China (7).
    keywords: covid-19; group; patients; pneumonia
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        item: #5653 of 7819
          id: cord-327432-ogw27tob
      author: Zhang, Feng-jian
       title: Expert Consensus on Nurses’ Human Caring for COVID-19 Patients in Different Sites
        date: 2020-08-07
       words: 3322
      flesch: 34
     summary: Patients with common fever, suspected infection, and confirmed COVID-19 infection, should be classified and managed in different ways by following guidelines; (10) Assess the basic needs of patients, and provide warm food and warm water according to their needs. Invite the psychologist or relevant specialist to intervene for severe psychological problems; (7) Assist patients in arranging further consultation and other matters; (8) Record the patient's special problems or conditions for other healthcare workers to pay attention to in future follow-up; (9) Provide necessary assistance for patients to return to their work; (1) Receive patient forwardly and warmly with polite manner and moderate voice, and introduce the name and role to the patients; (2) Keep the clinic area spacious, and decorate the area with clear signs, warm colors, green plants, and positive energy posters; (3) Design a quick physical examination process, guide the recovered person to finish the examination at different times.
    keywords: caring; covid-19; health; human; needs; patients; treatment
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        item: #5654 of 7819
          id: cord-327438-c5gzlfwi
      author: Mui, Leonora W.
       title: Thromboembolic complications of COVID-19
        date: 2020-11-07
       words: 2601
      flesch: 36
     summary: Initial clinical reports of COVID-19 patients focused on respiratory symptoms and chest CT imaging findings of bilateral groundglass opacities with peripheral and basal distribution [7, 8] . The identification of useful serum markers to assess patients at risk for thromboembolic events, including inflammatory markers such as D-dimer and fibrinogen levels, may help stratify coagulopathic risks in COVID-19 patients and identify specific cohorts who may derive significant clinical benefits from anticoagulation therapy [18] [19] [20] .
    keywords: arterial; covid-19; fig; hospital; patients; right; thrombosis
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        item: #5655 of 7819
          id: cord-327442-e02y93f6
      author: Kastritis, Efstathios
       title: Systemic autoimmune diseases, anti-rheumatic therapies, COVID-19 infection risk and patient outcomes
        date: 2020-07-11
       words: 4050
      flesch: 32
     summary: Treatment adherence of patients with systemic rheumatic diseases in COVID-19 pandemic COVID-19, rheumatic diseases and immunosuppressive drugs: an appeal for medication adherence Coronavirus disease 2019 (COVID-19) and anti-rheumatic drugs Virusassociated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus COVID-19: a new virus, but a familiar receptor and cytokine release Syndrome The many faces of the anti-COVID immune response Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Current concepts in the diagnosis and management of cytokine release syndrome Recommendations for the management of hemophagocytic lymphohistiocytosis in adults On the alert for cytokine storm: immunopathology in COVID-19 Immunosuppression for hyperinflammation in COVID-19: a double-edged sword? Risk of serious infection in biological treatment of patients with rheumatoid arthritis: a systematic review and meta-analysis Risk factors for reported influenza and influenza-like symptoms in patients with rheumatoid arthritis Greek Rheumatology Society and Professional Association of Rheumatologists (ERE-EPERE) (2020) Recommendations regarding COVID-19 infection in rheumatic patients in Greece Impact of low dose tocilizumab on mortality rate in patients with COVID-19 related pneumonia Scarpellini P, Dagna L (2020) Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study Effective treatment of severe COVID-19 patients with tocilizumab Favorable Anakinra responses in severe COVID-19 patients with secondary hemophagocytic lymphohistiocytosis Baricitinib for COVID-19: a suitable treatment? Baricitinib as potential treatment for 2019-nCoV acute respiratory disease COVID-19: combining antiviral and antiinflammatory treatments Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a 6-day follow up: a pilot observational study Observational study of hydroxychloroquine in hospitalized patients with Covid-19 A rush to judgment? Clinical course of COVID-19 in a series of patients with chronic arthritis treated with immunosuppressive targeted therapies Rheumatic disease and COVID-19: initial data from the COVID-19 Global Rheumatology Alliance provider registries Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physicianreported registry Incidence and clinical course of COVID-19 in patients with connective tissue diseases: a descriptive observational analysis Rituximab for granulomatosis with polyangiitis in the pandemic of covid-19: lessons from a case with severe pneumonia A (2020) Identifying rheumatic disease patients at high risk and requiring shielding during the COVID-19 pandemic WHO Coronavirus Disease Geoepidemiology of autoimmune rheumatic diseases COVID-19 pandemic: is a gender-defined dosage effect responsible for the high mortality rate among males Conflict of interest None for this manuscript, for all authors.
    keywords: anti; covid-19; data; diseases; hydroxychloroquine; infection; patients; risk
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        item: #5656 of 7819
          id: cord-327481-m9r0p84v
      author: Duployez, Nicolas
       title: Clinico-Biological Features and Clonal Hematopoiesis in Patients with Severe COVID-19
        date: 2020-07-21
       words: 3867
      flesch: 40
     summary: Serum profiling of COVID-19 patients has revealed a distinct inflammatory response characterized by high levels of interleukin-6 (IL-6) and reduced type I interferon Overall, mutations in DNMT3A and/or TET2 were present in 36% (44/122) of COVID-19 patients and were found in 80% (44/55) of those with CH.
    keywords: cohort; covid-19; hematopoiesis; mutations; patients; tet2; years
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        item: #5657 of 7819
          id: cord-327486-hu1clc79
      author: Cobianchi, Lorenzo
       title: To a New Normal: Surgery and COVID-19 during the Transition Phase
        date: 2020-06-02
       words: 1695
      flesch: 47
     summary: The acknowledgement of the many unknown risks is essential in the ethical care of surgical patients going forward. 1 Healthcare facilities have been challenged to adapt rapidly to treat an increasing number of COVID-19 patients.
    keywords: covid-19; patients; phase; surgery; transition
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        item: #5658 of 7819
          id: cord-327504-4kf9mgy8
      author: Sklar, David P.
       title: COVID-19: Lessons From the Disaster That Can Improve Health Professions Education
        date: 2020-06-22
       words: 2926
      flesch: 46
     summary: Surveillance for disease, investment in disease and injury prevention, and disaster planning should be basic elements of health professions education. I imagined the journal would continue its focus on topics such as competency-based education, professionalism, workforce diversity wellness, new technologies for education, and other innovations in health professions education.
    keywords: care; covid-19; disease; education; health
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        item: #5659 of 7819
          id: cord-327511-e3idvknz
      author: Trifan, G.
       title: Characteristics of a Diverse Cohort of Stroke Patients with SARS-CoV-2 and Outcome by Sex
        date: 2020-09-11
       words: 3486
      flesch: 49
     summary: The effect of sex on stroke patients with SARS-CoV-2 infection has not been investigated. In our cohort, we observed that the presentation of stroke patients with SARS-CoV-2 was more pleomorphic with almost 40% of our cases having mild to moderate symptoms of COVID-19 or being asymptomatic at presentation.
    keywords: cov-2; covid-19; females; males; patients; sars; stroke; study
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        item: #5660 of 7819
          id: cord-327543-kibjwfad
      author: Ong, S. J.
       title: SIR HELMET (Safety In Radiology HEalthcare Localised Metrological EnviromenT): a low-cost negative-pressure isolation barrier for shielding MRI frontline workers from COVID-19 exposure
        date: 2020-07-01
       words: 1494
      flesch: 43
     summary: • Does not affect MRI image quality even on the most sensitive sequences. In addition to assessing its functionality, the present study also evaluates the impact of the shield on MRI image quality.
    keywords: covid-19; healthcare; helmet; mri; patients
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        item: #5661 of 7819
          id: cord-327544-7ws2kleo
      author: Hammoumi, Aayah
       title: Impact assessment of containment measure against COVID-19 spread in Morocco
        date: 2020-08-22
       words: 3927
      flesch: 47
     summary: Taking account of the previous assumptions, the dynamics of COVID-19 can be described as follows: Susceptibles (S) contacted with either unreported symptomatic (Ĩ u ) or asymptomatic infectious individuals (Ã), at an effective contact rate, c, are infected with infection probability, β, and move to the asymptomatic infectious class (Ã). key: cord-327544-7ws2kleo authors: Hammoumi, Aayah; Qesmi, Redouane title: Impact assessment of containment measure against COVID-19 spread in Morocco date: 2020-08-22 journal: Chaos Solitons Fractals DOI: 10.1016/j.chaos.2020.110231 sha: doc_id: 327544 cord_uid: 7ws2kleo Since the appearance of the first case of COVID-19 in Morocco on March, 02,2020, the cumulative number of reported infectious cases continues to increase and, up to date, the peak-time of infection is not reached yet.
    keywords: asymptomatic; cases; containment; covid-19; epidemic; morocco
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        item: #5662 of 7819
          id: cord-327575-5pcnuqgy
      author: Morrisette, Taylor
       title: The Pharmacokinetic and Pharmacodynamic Properties of Hydroxychloroquine and Dose Selection for COVID-19: Putting the Cart Before the Horse
        date: 2020-08-01
       words: 5456
      flesch: 41
     summary: In healthy males who received a single HCQ 200 mg oral dose, a mean peak blood HCQ concentration of 0.1296 mcg/ml was achieved in 3.26 h, while a peak plasma HCQ concentration of 0.0503 mcg/ ml was achieved in 3.74 h. Tett and colleagues performed a randomized, crossover study in which the HCQ 155 mg oral tablet was compared to an intravenous infusion of racemic HCQ 155 mg to evaluate the absolute bioavailability of the commercially available HCQ tablet. Maisonnasse and colleagues found that HCQ concentrations in the lung were higher than in plasma, with lung:plasma ratios ranging from 27 to 177 in macaques [25] .
    keywords: cov-2; covid-19; hcq; hydroxychloroquine; patients; sars; studies; values
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        item: #5663 of 7819
          id: cord-327578-9r1fxfn4
      author: Bluro, Ignacio Martín
       title: ‘Cardiovascular Pandemic’ in Argentina
        date: 2020-07-30
       words: 1178
      flesch: 42
     summary: The few existing telemedicine platforms belong to private healthcare systems, which prevents access to those vulnerable and with limited financial resources. A recent report by ADECRA+CEDIM, an industry group that represents private healthcare systems nationwide, revealed a 62% decline in consultations to emergency rooms due to coronary syndrome and a 46% decrease in calls for stroke, which led to a 59% reduction in the number of coronary angioplasties and a 58% reduction in central cardiac surgeries [13] .
    keywords: access; cardiovascular; covid-19; healthcare
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        item: #5664 of 7819
          id: cord-327586-06r1ifuy
      author: Zhao, Yue
       title: Atypical Computed Tomography Presentations of Coronavirus Disease 2019
        date: 2020-08-07
       words: 2254
      flesch: 40
     summary: f evaluate whether the chest CT manifestations of COVID-19 patients were typical and Kappa value was calculated. Methods The clinical and chest CT imaging data of 16 patients diagnosed with COVID-19 were retrospectively analyzed, and patients with atypical CT presentations were selected for analysis and review.
    keywords: covid-19; opacities; patients
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        item: #5665 of 7819
          id: cord-327595-00fxzyhq
      author: None
       title: American Geriatrics Society (AGS) Policy Brief: COVID‐19 and Assisted Living Facilities
        date: 2020-05-14
       words: 3210
      flesch: 46
     summary: Ensuring access to paid leave is important for ALF staff, including certified nursing assistants, personal care assistants, dietary staff, direct care workers, and environmental support staff, as well as home care workers who are paid hourly, often lack paid sick leave, and commonly have marginal financial resources at baseline. While residents could be restricted to their rooms, it would require significant staff to provide needed care, and residents would need to agree to adhere to such restrictions, which makes it difficult to enforce such universal precautions.
    keywords: alfs; care; covid-19; health; home; need; residents; staff
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        item: #5666 of 7819
          id: cord-327600-xa6uibi8
      author: Roland, Lauren T.
       title: In Reply: Challenges in interpreting the diagnostic performance of symptoms to predict COVID‐19 status: the case of anosmia
        date: 2020-06-25
       words: 798
      flesch: 44
     summary: Unfortunately, even now, no steady state of COVID-19 disease This article is protected by copyright. It will be vital to understand how details of olfactory impairment, severity and timing can differentiate and predict COVID-19 disease presence, severity and overall health recovery.
    keywords: covid-19; testing
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        item: #5667 of 7819
          id: cord-327607-g0jtrwot
      author: Weinberg, Marc Scott
       title: Clinical Trials and Tribulations in the COVID-19 Era
        date: 2020-05-19
       words: 4316
      flesch: 31
     summary: This creates a dual challenge, as not only do study partners assist with coordinating visits, but one of their primary roles in several clinical studies is study partner assessment; study partners, who contribute significantly to behavioral and cognitive assessments during visits, are intended to have contact with the subject a minimum of two days per week, which is less of a problem when the partner is a spouse or lives in the home with the subject. As there are currently no FDA-approved disease-modifying therapies for Alzheimer's disease, volunteers participating in clinical trials for a potential disease-modifying drug often endorse the same goal: Let me do everything in my power to take back control of this disease or help others who come after me.
    keywords: alzheimer; assessment; covid-19; disease; person; research; safety; study; subjects; trials; visits
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        item: #5668 of 7819
          id: cord-327616-uu9uygic
      author: Wazny, Vanessa
       title: Vascular underpinning of COVID-19
        date: 2020-08-27
       words: 6998
      flesch: 28
     summary: In vitro modelling of human endothelial cells derived from distinct tissues has shown that the flavivirus nonstructural protein 1, from dengue, Zika, West Nile, Japanese encephalitis and yellow fever viruses, binds to endothelial cells and disrupts the endothelial glycocalyx components, triggering hyperpermeability and vascular dysfunction, in a tissue-specific manner A associated with human immunodeficiency virus type 1 were found by proteomics by using two-dimensional gel electrophoresis and matrix-assisted laser desorption ionization-time of flight mass spectrometry SARS-CoV-2 invades host cells via a novel route: CD147-spike protein Clinical study of anti-CD147 humanized meplazumab for injection to treat with 2019-nCoV pneumonia Tissue distribution of basigin and monocarboxylate transporter 1 in the adult male mouse: a study using the wild-type and basigin gene knockout mice 2020 CD147 (BSG) but not ACE2 expression is detectable in vascular endothelial cells within single cell RNA sequencing datasets derived from multiple tissues in healthy individuals Function of CD147 in atherosclerosis and atherothrombosis Autophagy as a regulated pathway of cellular degradation Selective autophagy and xenophagy in infection and disease.
    keywords: ace2; angiotensin; cd147; cells; covid-19; disease; endothelial; entry; expression; infection; patients; sars; study; syndrome; vascular
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        item: #5669 of 7819
          id: cord-327622-ezgufe24
      author: Kaur, Ramandeep
       title: Practical strategies to reduce nosocomial transmission to healthcare professionals providing respiratory care to patients with COVID-19
        date: 2020-09-23
       words: 6338
      flesch: 37
     summary: Influenza Other Respir Viruses Dynamics of infectious disease transmission by inhalable respiratory droplets Guidelines for preventing the transmission of Mycobacterium tuberculosis in health-care settings Survival of influenza viruses on environmental surfaces Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1 High-flow nasal cannula for COVID-19 patients: low risk of bio-aerosol dispersion Dispersal of respiratory droplets with open vs closed oxygen delivery masks: implications for the transmission of severe acute respiratory syndrome Year in review 2019: high-flow nasal cannula (HFNC) oxygen therapy for adult patients High flow nasal cannula compared with conventional oxygen therapy for acute hypoxemic respiratory failure: a systematic review and meta-analysis Use of high flow nasal therapy to treat moderate to severe hypoxemic respiratory failure in Exhaled air dispersion during high flow nasal cannula therapy versus CPAP via different masks Preliminary findings on control of dispersion of aerosols and droplets during high-velocity nasal insufflation therapy using a simple surgical mask: implications for the high-flow nasal cannula Acute febrile respiratory illness in the ICU: reducing disease transmission Expert Consensus on Preventing Nosocomial Transmission During Respiratory Care for Critically Ill Patients Infected by 2019 Novel coronavirus pneumonia Everyone with asthma should have a metered dose inhaler and a spacer Nasal high flow in management of children with status asthmaticus: a retrospective observational study Epoprostenol delivered via high flow nasal cannula for ICU subjects with severe hypoxemia comorbid with pulmonary hypertension or right heart dysfunction The clinical impact of flow titration on epoprostenol delivery via high flow nasal cannula for ICU patients with pulmonary hypertension or right ventricular dysfunction: a retrospective cohort comparison study The ratio of nasal cannula gas flow to patient inspiratory flow on trans-nasal pulmonary aerosol delivery for adults: an in vitro study Decrease the flow setting to improve trans-nasal pulmonary aerosol delivery via high-flow nasal cannula to infants and toddlers Effect of noninvasive ventilation delivered by helmet vs face mask on the rate of endotracheal intubation in patients with acute respiratory distress syndrome: a randomized clinical trial Noninvasive ventilation of patients with acute respiratory distress syndrome. Influenza Other Respir Viruses Exhaled air dispersion during noninvasive ventilation via helmets and a total facemask Staff safety during emergency airway management for COVID-19 in Hong Kong Practical recommendations for critical care and anesthesiology teams caring for novel coronavirus (2019-nCoV) patients Emergency tracheal intubation in 202 patients with COVID-19 in Wuhan, China: lessons learnt and international expert recommendations ventilatory and intensive care Expert recommendations for tracheal intubation in critically ill patients with noval coronavirus disease Barrier enclosure during endotracheal intubation New device and technique to protect intubation operators against COVID-19 COVID-19): anesthetic concerns, including airway management and infection control High-flow nasal cannula therapy as apneic oxygenation during endotracheal intubation in critically ill patients in the intensive care unit: a systematic review and metaanalysis Mask ventilation and dispersion of exhaled air Effect of ventilator circuit changes on ventilator-associated pneumonia: a systematic review and meta-analysis Trends in tracheostomy for mechanically ventilated patients in the United States Tracheotomy in ventilated patients with COVID-19 CORONA-steps for tracheotomy in COVID-19 patients: a staff-safe method for airway management Negativepressure aerosol cover for COVID-19 tracheostomy Does endotracheal tube clamping prevent air leaks and maintain positive endexpiratory pressure during the switching of a ventilator in a patient in an intensive care unit?
    keywords: aerosol; air; covid-19; dispersion; filter; flow; intubation; mask; nasal; patients; respiratory; transmission; ventilation
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        item: #5670 of 7819
          id: cord-327628-fl8dyahe
      author: Yuan, Qi
       title: Spatiotemporal variations and reduction of air pollutants during the COVID-19 pandemic in a megacity of Yangtze River Delta in China
        date: 2020-08-20
       words: 2942
      flesch: 43
     summary: key: cord-327628-fl8dyahe authors: Yuan, Qi; Qi, Bing; Hu, Deyun; Wang, Junjiao; Zhang, Jian; Yang, Huanqiang; Zhang, Shanshan; Liu, Lei; Xu, Liang; Li, Weijun title: Spatiotemporal variations and reduction of air pollutants during the COVID-19 pandemic in a megacity of Yangtze River Delta in China date: 2020-08-20 journal: Sci Total Environ DOI: 10.1016/j.scitotenv.2020.141820 sha: doc_id: 327628 cord_uid: fl8dyahe Abstract In recent decades, air pollution has become an important environmental problem in the megacities of eastern China. The COVID-19 outbreak has prompted a nationwide public lockdown period and provides a valuable opportunity for understanding the sources and factors of air pollutants.
    keywords: air; covid; industry; period; pollutants; urban
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        item: #5671 of 7819
          id: cord-327629-ep28ay11
      author: Herron, J.B.T.
       title: Coronavirus antibody positive tests and continued use of personal protective equipment throughout the pandemic
        date: 2020-06-20
       words: 1175
      flesch: 43
     summary: -Face masks, eye protection and person distancing: systematic review and meta-analysis High-profile coronavirus retractions raise concerns about data oversight COVID-19 infodemic: More retweets for science-based information on coronavirus than for false information A pneumonia outbreak associated with a new CoV-2 through the postpandemic period Reducing medical error during a pandemic Generational and Occupational Differences in Human Factors Knowledge and Awareness: A Comparison Study Mission command: applying principles of military leadership to the SARS-CoV-2 (COVID-19) crisis Laboratory diagnosis and monitoring the viral shedding of 2019-nCoV infections Persistence and clearance of viral RNA in 2019 novel coronavirus disease rehabilitation patients Covid-19: Antibody tests will not be rolled out in UK until at least May, MPs hear COVID-19 immunity passports and vaccination certificates: scientific, equitable, and legal challenges expert reaction to PHE laboratory evaluations of Roche and Abbott antibody tests. As mentioned in a recent publication current Covid-19 antibody tests are similar to the first-generation HIV tests (17) .
    keywords: antibody; covid-19; staff; tests
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        item: #5672 of 7819
          id: cord-327631-mqr5fd40
      author: Sullivan, Amy B
       title: The COVID-19 Crisis: A Mental Health Perspective and Response Using Telemedicine
        date: 2020-05-11
       words: 3712
      flesch: 45
     summary: Therefore, mental health services have been incorporated from an enterprise-wide level to address concerns for both patients and healthcare providers impacted from COVID-19. key: cord-327631-mqr5fd40 authors: Sullivan, Amy B; Kane, Alexa; Roth, Alicia J; Davis, Bryan E; Drerup, Michelle L; Heinberg, Leslie J title: The COVID-19 Crisis: A Mental Health Perspective and Response Using Telemedicine date: 2020-05-11 journal: J Patient Exp DOI: 10.1177/2374373520922747 sha: doc_id: 327631 cord_uid: mqr5fd40 With the outbreak of COVID-19, patients and providers were forced to isolate and become innovative in ways to continue exceptional patient care.
    keywords: care; center; cleveland; clinic; covid-19; health; patient; psychology; services
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        item: #5673 of 7819
          id: cord-327632-2hz94uuw
      author: Lv, Na
       title: Management of oral medicine emergencies during COVID-19: A study to develop practice guidelines
        date: 2020-08-07
       words: 2815
      flesch: 38
     summary: A brief summary and discussion on the management of oral medicine patients during COVID-19 emergency are proposed as follows, focusing on remote assistance devices and classification of emergencies. key: cord-327632-2hz94uuw authors: Lv, Na; Sun, Ming; Polonowita, Ajith; Mei, Li; Guan, Guangzhao title: Management of oral medicine emergencies during COVID-19:
    keywords: cell; conferencing; covid-19; emergencies; management; medicine; patient; video
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        item: #5674 of 7819
          id: cord-327650-6afsk8ix
      author: Ward, Jeremy K.
       title: The French public's attitudes to a future COVID-19 vaccine: The politicization of a public health issue
        date: 2020-10-06
       words: 4349
      flesch: 45
     summary: Presses universitaires de Rennes More Americans now see 'very high' preventive health benefits from measles vaccine Beliefs about childhood vaccination in the United States: political ideology, false consensus, and the illusion of uniqueness Psychosocial and demographic characteristics relating to vaccine attitudes in Australia Factors in vaccination intention against the pandemic influenza A/H1N1 Majority acceptance of vaccination and mandates across the political spectrum in Australia De la gestion des risques à la production de la sécurité Rethinking the antivaccine movement concept: a case study of public criticism of the swine flu vaccine's safety in France Vaccine hesitancy and coercion: all eyes on France New Yahoo News/YouGov poll shows coronavirus conspiracy theories spreading on the right may hamper vaccine efforts Ensuring global access to COVID-19 vaccines This work was supported by grants from the Agence Nationale de la Recheche (ANR-20-COVI-0035-01) and the CNRS (Momentum, to JKW). In countries where vaccine hesitancy was widespread before the COVID-19 epidemic, will it affect the coronavirus vaccination campaign?
    keywords: attitudes; covid-19; future; people; right; vaccination; vaccine
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        item: #5675 of 7819
          id: cord-327652-tn29r8lj
      author: Fretheim, Atle
       title: Rapid reviews for rapid decision-making during the coronavirus disease (COVID-19) pandemic, Norway, 2020
        date: 2020-05-14
       words: 1593
      flesch: 41
     summary: Oslo: Folkehelseinstituttet COVID-19: The relationship between age, comorbidity and disease severity -a rapid review, 1st update A taxonomy of rapid reviews links report types and methods to specific decision-making contexts Keep up with the latest coronavirus research Rapid HTA of alternative diagnostic technologies for the detection of SARS-CoV-2. key: cord-327652-tn29r8lj authors: Fretheim, Atle; Brurberg, Kjetil G; Forland, Frode title: Rapid reviews for rapid decision-making during the coronavirus disease (COVID-19) pandemic, Norway, 2020 date: 2020-05-14 journal: Euro Surveill DOI: 10.2807/1560-7917.es.2020.25.19.2000687 sha: doc_id: 327652 cord_uid: tn29r8lj In response to urgent needs for updated evidence for decision-making on various aspects related to coronavirus disease (COVID-19), the Norwegian Institute of Public Health established a rapid review team.
    keywords: covid-19; disease; evidence; health; review
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        item: #5676 of 7819
          id: cord-327653-2gn9h4i2
      author: Vallinoto, Antonio Carlos Rosário
       title: The challenges of COVID-19 in the Brazilian Amazonian communities and the importance of seroepidemiological surveillance studies
        date: 2020-08-15
       words: 1721
      flesch: 23
     summary: According to the National Committee for Indigenous Life and Memory, a third of Brazilian indigenous populations, a total of 111 groups (44 ethnicities), would have already been affected by COVID-19, with more than 7000 infected and 300 deaths; this led the National Council of Justice (CNJ) of Brazil to create an observatory to monitor the protection of indigenous peoples [9] . Researchers from the Oswaldo Cruz Foundation (FIO-CRUZ) and the Getulio Vargas Foundation (FGV) produced a report on the risk of COVID-19 spreading among indigenous populations, according to the geographic and sociodemographic vulnerability of this segment.
    keywords: communities; coronavirus; cov-2; health; indigenous; sars
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        item: #5677 of 7819
          id: cord-327697-80msva10
      author: Sarı, Cenk
       title: The outcomes of the postulated interaction between SARS-CoV-2 and the renin-angiotensin system on the clinician’s attitudes toward hypertension treatment
        date: 2020-11-09
       words: 3555
      flesch: 41
     summary: Conversely, 27% of cardiologists, 13% of internal medicine specialists, 8% of general practitioners, and 6% of family medicine physicians had positive opinions that these medications could be associated with less severe disease and could be protective against infection of COVID-19 disease (Fig. 5b) . Professional societies have navigated this ambiguity by recommending that patients should continue to use ACE inhibitors or ARBs [10] .
    keywords: ace; angiotensin; arbs; covid-19; pandemic; physicians; study; treatment
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        item: #5678 of 7819
          id: cord-327720-m6cofbj6
      author: Chakrabarti, Amitabha
       title: Understanding the practice of thoracic surgery during the COVID-19 pandemic
        date: 2020-08-11
       words: 2776
      flesch: 44
     summary: The procedures that can be carried out in a hospital are based on the prevalence of COVID-19 patients within the hospital and availability of hospital resources. Based on the prevalence of COVID-19 patients within the hospital, availability of hospital resources, and the rate of change (in terms of increasing prevalence of infections and resource depletion), a compass statement has been introduced giving additional direction to navigate volume restriction, based on perceived risk to patients and hospital staff.
    keywords: covid-19; health; hospital; pandemic; patients; risk; surgery; thoracic
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        item: #5679 of 7819
          id: cord-327764-4nlg26p5
      author: Sun, Da-wei
       title: The underlying changes and predicting role of peripheral blood inflammatory cells in severe COVID-19 patients: a sentinel?
        date: 2020-05-14
       words: 5153
      flesch: 44
     summary: Thus, it is assumed by this study that the functional damage of CD4+T cells makes COVID-19 patients susceptible to severe disease, and the excessive exhaustion of CD8+T cells impairs cellular immune response to 2019-nCoV in severe patients [27] . Importantly, it may be that the functional damage of CD4+T cells that makes COVID-19 patients susceptible to severe disease, and the excessive exhaustion of CD8+T cells that impairs cellular immune response to 2019-nCoV in severe patients according to the literature review [27] .
    keywords: blood; cases; cells; covid-19; disease; group; lung; patients; study; type
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        item: #5680 of 7819
          id: cord-327770-4u250y8x
      author: Bajwa, Ali
       title: What the papers say
        date: 2020-10-26
       words: 1728
      flesch: 38
     summary: Massive cutback in orthopaedic healthcare services due to the COVID-19 pandemic Recommendations to optimize the safety of elective surgical care while limiting the spread of COVID-19: primum non nocere [3] report that this study was undertaken with the aim to investigate current possible cutbacks in orthopaedic healthcare due to the COVID-19 pandemic.
    keywords: authors; covid-19; healthcare; orthopaedic; pandemic
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        item: #5681 of 7819
          id: cord-327776-bxpay7ic
      author: Sayari, Arash J.
       title: Personal Health of Spine Surgeons Can Impact Perceptions, Decision-Making and Healthcare Delivery During the COVID-19 Pandemic - A Worldwide Study
        date: 2020-06-30
       words: 3702
      flesch: 40
     summary: Future perceptions and financial impacts from COVID-19 were also linked to spine surgeon health. Questions addressed demographics, impacts and perceptions of COVID-19, and the presence of surgeon comorbidities, which included cancer, cardiac disease, diabetes, obesity, hypertension, respiratory illness, renal disease, and current tobacco use.
    keywords: comorbidities; covid-19; health; spine; surgeons
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        item: #5682 of 7819
          id: cord-327779-lt3t4shi
      author: Gilad, Vered
       title: Treatment of COVID-19 Patients in Italy: A Physician’s Experience and Insights
        date: 2020-07-31
       words: 2311
      flesch: 33
     summary: While the number of COVID-19 patients was rapidly increasing, Italy saw a drastic decrease in hospital admissions for other pathologies, since patients were afraid of contracting the infection at the hospital. Given the limited clinical experience and lack of evidence-based data, new channels for relaying updates emerged; doctors who first started seeing COVID-19 patients primarily shared their experience and findings through Internet pathways.
    keywords: covid-19; hospital; italy; number; patients; treatment
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        item: #5683 of 7819
          id: cord-327787-vlbpijqg
      author: Casalino, Giuseppe
       title: Coronavirus disease 2019 presenting with conjunctivitis as the first symptom
        date: 2020-04-28
       words: 510
      flesch: 40
     summary: Clinical characteristics of coronavirus disease 2019 in China Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection The possibility of COVID-19 transmission from eye to nose. The present case outlines the importance of questioning patients presenting with conjunctivitis about respiratory and other systemic symptoms which should prompt clinicians to rule out COVID-19 infection.
    keywords: conjunctivitis; covid-19
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        item: #5684 of 7819
          id: cord-327821-c6ncyge7
      author: Rosemary HM Lim, Dr
       title: The experiences of the community pharmacy team in supporting people with dementia and family carers with medication management during the COVID-19 pandemic.
        date: 2020-10-17
       words: 2968
      flesch: 47
     summary: The impact of these changes on the provision of medication services to people with dementia is underexplored. An interpretivist/constructivist research paradigm was used; semi-structured one-to-one telephone interviews were conducted with any member of the community pharmacy team who had been involved in providing medication services to people with dementia in England before and during the COVID-19 pandemic.
    keywords: covid-19; dementia; medication; pandemic; people; services
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        item: #5685 of 7819
          id: cord-327827-oliw4ee5
      author: Sweid, Ahmad
       title: Letter: Thrombotic Neurovascular Disease in COVID-19 Patients
        date: 2020-06-04
       words: 1051
      flesch: 44
     summary: Unusual trends have been seen in AIS patients who are COVID-19 positive; while it is too early to establish direct causality, our preliminary data can be used to raise awareness in the population. Moreover, cerebrovascular insult was the primary manifestation of COVID-19 in patients who did not have the fulminant virus manifestations present.
    keywords: covid-19; occlusion; patients; sars
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        item: #5686 of 7819
          id: cord-327836-6o66a4i5
      author: Zuily, S
       title: Thrombose artérielle et veineuse au cours du COVID-19
        date: 2020-08-07
       words: 2180
      flesch: 44
     summary: Même si les caractéristiques des patients COVID-19 semblent différentes, l'absence de données scientifiques incite à adopter les mêmes attitudes médicamenteuses qu'avec les patients sans COVID-19. [2, 3] chez les patients présentant un COVID-19 nécessitant une hospitalisation et entre 17 %
    keywords: cours; covid-19; des; les; par; patients; pour; une
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        item: #5687 of 7819
          id: cord-327842-5h54azyy
      author: Ertan, Deniz
       title: COVID-19: urgency for distancing from domestic violence
        date: 2020-09-04
       words: 2965
      flesch: 43
     summary: Domestic violence is a public health and human rights issue that primarily affects women and children worldwide. The COVID-19 health crisis is exacerbating another pre-existing public health problem by increasing the severity and frequency of domestic violence, thus demonstrating the need to adopt significant and long-term measures.
    keywords: covid-19; increase; measures; pandemic; violence; women
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        item: #5688 of 7819
          id: cord-327886-vvm1gfku
      author: Burstyn, Igor
       title: Towards reduction in bias in epidemic curves due to outcome misclassification through Bayesian analysis of time-series of laboratory test results: case study of COVID-19 in Alberta, Canada and Philadelphia, USA
        date: 2020-06-06
       words: 4615
      flesch: 46
     summary: In an ongoing epidemic, where test sensitivity (Sn) and specificity (Sp) of case ascertainment are fixed, prevalence of the outcome (infection), determines whether false positives or negatives dominate. As discussed at more length in Appendix B in the Supplemental Material, this model formulation neither rules in, nor rules out, learning about test sensitivity and specificity from the reported data.
    keywords: cases; covid-19; data; epidemic; sensitivity; testing; tests; time
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        item: #5689 of 7819
          id: cord-327894-b0bsseui
      author: Pecellín, Lidia Gestoso
       title: Recomendaciones y uso de los diferentes tipos de test para detección de infección por SARS-COV-2
        date: 2020-10-14
       words: 4899
      flesch: 42
     summary: La enfermera que proceda a la obtención de muestra deberá llevar un equipo de protección individual para prevenir la transmisión de la infección de acuerdo con el riesgo de exposición 31 . La táctica para la contención de la epidemia fue la realización de tests masivos para conocer el número de personas contagiadas 1 .
    keywords: anticuerpos; casos; centros; como; con; coronavirus; cov-2; covid-19; de la; del; detección; diagnóstico; infección; las; los; muestras; más; pacientes; para; para la; pcr; por; pruebas; que; recogida; sars; según; ser; son; tests; toma; una; virus
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        item: #5690 of 7819
          id: cord-327906-m00ua3x1
      author: Pantanetti, Paola
       title: Potential role of incretins in diabetes and COVID-19 infection: a hypothesis worth exploring
        date: 2020-06-26
       words: 1851
      flesch: 36
     summary: Interestingly, as gliptins are known to have little or no hypoglycemic effects [14, 15] , they might be used safely also in non-diabetic patients. Furthermore, dipeptidyl peptidase 4 (DPP4) enzyme is highly expressed in the lung, and that it may have additional actions besides its effects on glucose metabolism, which might exert profound pro-inflammatory effects.
    keywords: cells; covid-19; dpp4; lung; patients
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        item: #5691 of 7819
          id: cord-327924-q29lgopf
      author: Johnson, Jared
       title: The Impact of the COVID-19 Pandemic on Fellowship Training: A National Survey of Pediatric Otolaryngology Fellowship Directors
        date: 2020-06-23
       words: 2844
      flesch: 36
     summary: Overall, pediatric otolaryngology fellowship directors reported the COVID-19 pandemic has had a significant impact on the overall fellowship experience within the field of pediatric otolaryngology, with the majority feeling that both their fellows surgical and clinical experience have been significantly impacted. Overall, pediatric otolaryngology fellowship directors reported the COVID-19 pandemic has had a significant impact on the overall fellowship experience within the field of pediatric otolaryngology, with the majority feeling that both their fellows surgical and clinical experience have been significantly impacted.
    keywords: covid-19; directors; fellowship; otolaryngology; pandemic
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        item: #5692 of 7819
          id: cord-327933-u0fcs3yg
      author: Doná, Daniele
       title: Pediatric transplantation in Europe during the COVID‐19 pandemic: early impact on activity and healthcare
        date: 2020-08-12
       words: 2637
      flesch: 33
     summary: At this early stage in the pandemic very little information is available regarding the risk and burden of COVID-19 in pediatric transplant recipients as well as direction regarding protocols to be applied in this special population 9, 10 Dealing with this situation, several interventions aligned with international recommendations 11-13 have been implemented in pediatric transplant centers. All rights reserved almost half of pediatric transplant centers, a negative SARS-CoV-2 swab was also required as an additional admission criterion.
    keywords: article; cases; centers; covid-19; disease; patients; transplant; transplantation
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        item: #5693 of 7819
          id: cord-327963-dqsg84e5
      author: Tang, Suqin
       title: Mental Health and Its Correlates among Children and Adolescents during COVID-19 School Closure: The Importance of Parent-Child Discussion
        date: 2020-10-12
       words: 5152
      flesch: 42
     summary: The prevalence of depressive symptoms were 22.6% in primary school students (Xie et al., 2020) and 26.3% in secondary school students (Tang and Ying, 2020) . In China, secondary school students face more academic pressure than primary school students as they need to prepare for the zhongkao (entrance examination for senior secondary school) and gaokao (the national higher education entrance examination).
    keywords: adolescents; anxiety; children; depression; health; school; stress; students
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        item: #5694 of 7819
          id: cord-327976-pwe95zoi
      author: Singh, Dr Shweta
       title: Impact of COVID-19 and Lockdown on Mental Health of Children and Adolescents: A Narrative Review with Recommendations.
        date: 2020-08-24
       words: 5023
      flesch: 44
     summary: Quarantined parents/children Parents If child is separated to keeping contact as much as possible, being supportive and reassuring Coordinating with care givers, referring to mental health care professionals Foster care givers Being supportive, reassuring and educating Constructing and administring online questionnaires in order to detect psychological distress and other symptoms for children if they or their parents are quarantined, providing extra support to them and developing ad hoc supportive interventions. Impacts of COVID-19 on vulnerable children in temporary accommodation in the UK. Gunjan title: Impact of COVID-19 and Lockdown on Mental Health of Children and Adolescents: A Narrative Review with Recommendations. date: 2020-08-24 journal: Psychiatry Res DOI: 10.1016/j.psychres.2020.113429 sha: doc_id: 327976 cord_uid: pwe95zoi BACKGROUND: COVID-19 pandemic and lockdown has brought about a sense of fear and anxiety around the globe.
    keywords: adolescents; children; covid-19; health; lockdown; need; pandemic; parents; studies
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        item: #5695 of 7819
          id: cord-327989-6p39cx2e
      author: Everaert, Bert
       title: Emerging cardiological issues during the COVID‐19 pandemic
        date: 2020-05-16
       words: 1986
      flesch: 39
     summary: Furthermore, the pandemic puts stress on the organization of cardiac health care, both for COVID-19 patients as well as for the acute and chronic care of cardiac patients in which patient as well as physician-related delays in treatment could potentially lead to harm. In a recent report of Shi et al. 2 hospitalized COVID-19 patients in Wuhan, China, presenting with elevated high-sensitive cardiac troponin I levels had a higher frequency of complications such as ARDS (58.5% vs. 14.7%) and acute kidney injury (8.5 vs. 0.3%), required more invasive mechanical ventilation (22% vs. 4.2%) and had a significant increase in in-hospital mortality than patients without cardiac injury (51.2% vs. 4.5%).
    keywords: cardiac; covid-19; disease; patients; risk
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        item: #5696 of 7819
          id: cord-328011-6lf3no6u
      author: Zayed, Hatem
       title: Vaccine Development Against COVID-19 Prior to Pandemic Outbreaks, Using in vitro Evolution and Reverse Genetics
        date: 2020-08-14
       words: 1449
      flesch: 37
     summary: The Sleeping Beauty transposable element: evolution, regulation and genetic applications RNA virus reverse genetics and vaccine design Hemagglutinin amino acids related to receptor specificity could affect the protection efficacy of H5N1 and H7N9 avian influenza virus vaccines in mice SARS-associated coronavirus replication in cell lines Rapid generation of stable cell lines expressing high levels of erythropoietin, factor VIII, and an antihuman CD20 antibody using lentiviral vectors Production of virus-like particles for vaccination Therapeutic vaccines against infectious diseases Preliminary identification of potential vaccine targets for the COVID-19 coronavirus (SARS-CoV-2) based on SARS-CoV immunological studies Development of rabies virus-like particles for vaccine applications: production, characterization, and protection studies Lentivirus-based virus-like particles as a new protein delivery tool The author declares that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. A novel coronavirus from patients with pneumonia in China A new coronavirus associated with human respiratory disease in China Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Origin and evolution of pathogenic coronaviruses Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein Bat coronaviruses in China DNA shuffling and family shuffling for in vitro gene evolution Discovery of human-like Lasparaginases with potential clinical use by directed evolution.
    keywords: coronavirus; pandemic; vaccine; virus
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        item: #5697 of 7819
          id: cord-328036-tjm6sm6a
      author: Pai, Esha
       title: Continuing surgical care in cancer patients during the nationwide lockdown in the COVID‐19 pandemic—Perioperative outcomes from a tertiary care cancer center in India
        date: 2020-07-20
       words: 2186
      flesch: 42
     summary: key: cord-328036-tjm6sm6a authors: Pai, Esha; Chopra, Saumya; Mandloi, Deepak; Upadhyay, Arvind K.; Prem, Amar; Pandey, Durgatosh title: Continuing surgical care in cancer patients during the nationwide lockdown in the COVID‐19 pandemic—Perioperative outcomes from a tertiary care cancer center in India date: 2020-07-20 journal: J Surg Oncol DOI: 10.1002/jso.26134 sha: doc_id: 328036 cord_uid: tjm6sm6a BACKGROUND: In a region with milder impact of COVID‐19, treatment of cancer patients need not be deferred.
    keywords: cancer; covid-19; morbidity; patients; procedures
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        item: #5698 of 7819
          id: cord-328039-xt17gvcp
      author: Olson, Michael C.
       title: RadioGraphics Update: Venous Thrombosis and Hypercoagulability in the Abdomen and Pelvis—Findings in COVID-19
        date: 2020-07-10
       words: 1628
      flesch: 22
     summary: Some data suggest that the hypoxia induced by COVID-19 pneumonia may result in hypoxia-reperfusion and resultant cell death. In contradistinction, some studies have shown prolonged aPTT in patients with confirmed COVID-19, often in conjunction with the presence of lupus anticoagulant antibodies.
    keywords: covid-19; imaging; injury; patients; thrombosis
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        item: #5699 of 7819
          id: cord-328040-5qd05e4r
      author: Zhao, Xin-Ying
       title: Clinical characteristics of patients with 2019 coronavirus disease in a non-Wuhan area of Hubei Province, China: a retrospective study
        date: 2020-04-29
       words: 3419
      flesch: 50
     summary: To date, the clinical characteristics of COVID-19 patients in the non-Wuhan areas of Hubei Province in China have not been described. A considerable proportion of COVID-19 patients develop severe pneumonia, pulmonary edema, acute respiratory distress syndrome, and even multiple organ failure within a short time.
    keywords: cases; covid-19; disease; patients; sars; study; wuhan
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        item: #5700 of 7819
          id: cord-328053-urw0ry2n
      author: Mira, Estefanía
       title: Rapid recovery of a SARS-CoV-2 infected X-linked agammaglobulinemia patient after infusion of COVID-19 convalescent plasma
        date: 2020-07-08
       words: 168
      flesch: -24
     summary: Lesson from patients with 151 agammaglobulinemia Two X-154 linked agammaglobulinemia patients develop pneumonia as COVID-19 manifestation but recover Functional exhaustion 158 of antiviral lymphocytes in COVID-19 patients Convalescent Plasma for Critically Ill Patients With Severe Acute 162 Respiratory Syndrome Coronavirus 2 Infection Inhibition of Bruton tyrosine kinase in patients with severe 166 COVID-19 T cell exhaustion during persistent viral 168 infections Development of passive immunity against SARS-CoV-2 171 for management of immunodeficient patients -a perspective key: cord-328053-urw0ry2n authors: Mira, Estefanía; Yarce, Oscar A.; Ortega, Consuelo; Fernández, Silvia; Pascual, Natalia M.; Gómez, Cristina; Alvarez, Miguel A.; Molina, Ignacio J.; Lama, Rafael; Santamaria, Manuel title: Rapid recovery of a SARS-CoV-2 infected X-linked agammaglobulinemia patient after infusion of COVID-19 convalescent plasma date: 2020-07-08 journal: J Allergy Clin Immunol Pract DOI: 10.1016/j.jaip.2020.06.046 sha: doc_id: 328053 cord_uid: urw0ry2n nan 1 1 2 Antibodies, viruses and vaccines The Clinical 147 Observation of a CVID Patient Infected with COVID-19 A 150 possible role for B cells in COVID-19?
    keywords: covid-19
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        item: #5701 of 7819
          id: cord-328062-84pdw6p3
      author: Hendl, Tereza
       title: Pandemic Surveillance and Racialized Subpopulations: Mitigating Vulnerabilities in COVID-19 Apps
        date: 2020-08-25
       words: 3232
      flesch: 27
     summary: Following on our discussion of vulnerability and broader debates on the ethical risks related to COVID-19 pandemic responses (Devakumar et al. 2020; Lucivero et al. 2020 ), it appears that beside the necessity of effectiveness and respect for privacy and confidentiality, COVID-19 apps ought to be explicitly grounded in values that include justice, equality, solidarity, and user-benefit. Nevertheless, all population groups should be able to use COVID-19 surveillance technology that respects their privacy without exacerbating their vulnerability via exposure to discriminatory safety measures.
    keywords: apps; covid-19; data; health; pandemic; vulnerability
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        item: #5702 of 7819
          id: cord-328071-ulj2gtn3
      author: Sattari, Mahtab
       title: Evaluating Clinical Course and Risk Factors of Infection and Demographic Characteristics of Pregnant Women with COVID-19 in Hamadan Province, West of Iran
        date: 2020-08-17
       words: 3057
      flesch: 48
     summary: Pregnant women are at a higher risk of contracting viral infections including COVID-19. We aimed to evaluate the clinical course and risk factors of pregnant women diagnosed with COVID 19 in Hamadan Province, west of Iran.
    keywords: clinical; covid-19; disease; infection; pregnancy; symptoms; women
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        item: #5703 of 7819
          id: cord-328104-triub2h6
      author: Ibraheem Jabbar, Shaima
       title: Automated Analysis of Fatality Rates for COVID 19 across Different Countries
        date: 2020-09-26
       words: 2626
      flesch: 54
     summary: key: cord-328104-triub2h6 authors: Ibraheem Jabbar, Shaima title: Automated Analysis of Fatality Rates for COVID 19 across Different Countries date: 2020-09-26 journal: nan DOI: 10.1016/j.aej.2020.09.027 sha: doc_id: 328104 cord_uid: triub2h6 One of the significant parameters that helps in the reporting the highest risk areas, which have COVID 19 pandemic is case fatality rate (CFR). Case fatality rate (CFR) was evaluated using equation (1) for a set of countries across different continents in two months.
    keywords: countries; covid-19; fatality; rate; virus
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        item: #5704 of 7819
          id: cord-328113-eczjjc2v
      author: D’Alessandro, Angelo
       title: Serum Proteomics in COVID-19 Patients: Altered Coagulation and Complement Status as a Function of IL-6 Level
        date: 2020-07-30
       words: 4675
      flesch: 28
     summary: Nonetheless, to date, no study has measured coagulation protein levels in COVID-19 patients. While the levels of pro-inflammatory cytokines such as interleukin-6 (IL-6) have been associated with the severity of the disease, little is known about the impact of IL-6 levels on the proteome of COVID-19 patients.
    keywords: complement; cov-2; covid-19; covid-19 patients; disease; figure; il-6; il-6 levels; levels; patients; protein; sars; sera; serum
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        item: #5705 of 7819
          id: cord-328147-61gtx2h2
      author: Lopez-Mendez, Ivan
       title: Association of liver steatosis and fibrosis with clinical outcomes in patients with SARS-CoV-2 infection (COVID-19)
        date: 2020-10-21
       words: 2665
      flesch: 44
     summary: In COVID-19 patients, the prevalence of liver steatosis and advanced liver fibrosis by noninvasive assessment prediction models was high and was not associated with clinical outcomes; 96.8% of COVID-19 patients had at least one abnormal LFT. Liver function tests (LFT) abnormalities are reported in up to 50% of COVID-19 patients, metabolic comorbidities are associated with poorer outcomes.
    keywords: covid-19; fibrosis; liver; outcomes; patients; prevalence; study
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        item: #5706 of 7819
          id: cord-328163-kytnsrkq
      author: Zhang, Jin-nong
       title: Potential of Arbidol for Post-exposure Prophylaxis of COVID-19 Transmission—A Preliminary Report of a Retrospective Cohort Study
        date: 2020-05-30
       words: 1864
      flesch: 48
     summary: The Cox regression based on the data of the family members and health care workers with Arbidol or not showed that Arbidol PEP was a protective factor against the development of COVID-19 (HR 0.025, 95% CI 0.003–0.209, P=0.0006 for family members and HR 0.056, 95% CI 0.005–0.662, P=0.0221 for health care workers). The neurology department where the cluster of health care worker infections began is located in the internal medicine building, which is home to 800 medical beds.
    keywords: arbidol; care; covid-19; health; workers
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        item: #5707 of 7819
          id: cord-328169-ntg7b621
      author: Sun, Haiying
       title: Comparison of clinical and microbiological diagnoses for older adults with COVID-19 in Wuhan: a retrospective study
        date: 2020-07-08
       words: 3196
      flesch: 43
     summary: Clinical diagnosis Patients from epidemic areas who showed clinical (i.e., fever or respiratory symptoms) and laboratory (i.e., normal or decreased white blood cell counts, or decreased lymphocyte counts) features as well as imaging findings of viral pneumonia (i.e., ground-glass opacities, multifocal patchy consolidation, infiltration shadowing and interstitial abnormalities with a peripheral distribution) were clinically diagnosed as having COVID-19 by two experienced respiratory physicians [8] . The outcomes of clinically and microbiologically diagnosed cases before and after propensity score analyses OR odds ratio, CI confidence interval of OR, CAPS covariate adjustment using propensity score, PSM propensity score matching a One case of clinical diagnosis group was excluded from CAPS analysis for containing missing data in WBC count and LYM count b
    keywords: covid-19; diagnosis; groups; patients; propensity; score
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        item: #5708 of 7819
          id: cord-328181-b2o05j3j
      author: Nunez-Corrales, S.
       title: The Epidemiology Workbench: a Tool for Communities to Strategize in Response to COVID-19 and other Infectious Diseases
        date: 2020-07-25
       words: 11460
      flesch: 42
     summary: 3 Building a multi-objective model for COVID-19: the agent-based route Based on the discussion above, our current research efforts have focused on the development of an integrated simulation model capable of a) accurately reflecting known dynamics of the current pandemic and the qualitative results of other models, b) simulating data-driven stochastic heterogeneity across agent populations to more realistically reflect the variability of underlying human populations when the model is applied, c) integrating economic considerations in association with observable features of the pandemic, d) allowing detailed simulation of known public policy measures at different times, intensities and dates, and e) providing a simple interface for non-expert users to configure and interpret. an agent-based simulation model towards the definition of strategies for covid-19 second phase Demographic science aids in understanding the spread and fatality rates of covid-19 Model transparency and validation: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force-7 Fair allocation of scarce medical resources in the time of covid-19 The effectiveness of moral messages on public health behavioral intentions during the covid-19 pandemic Impact of non-pharmaceutical interventions (npis) to reduce covid19 mortality and healthcare demand The global community needs to swiftly ramp up the response to contain covid-19 Asymptomatic transmission, the achilles' heel of current strategies to control covid-19 Social protection and jobs responses to covid-19: a real-time review of country measures Us city-size distribution and space Ethics, information technology, and public health: duties and challenges in computational epidemiology Face masks for the public during the covid-19 crisis Optimal quarantine strategies for covid-19 control models Spread of sars-cov-2 in the icelandic population Variation in government responses to covid-19 Modeling targeted layered containment of an influenza pandemic in the united states Ecological pricing and economic efficiency Combining behavioral economics and infectious disease epidemiology to mitigate the covid-19 outbreak Temporal dynamics in viral shedding and transmissibility of covid-19 Wicked problems in public policy
    keywords: agents; asymptomatic; covid-19; disease; health; impact; july; license; measures; medrxiv; model; perpetuity; population; preprint; public; simulation; sir; testing; time; value
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        item: #5709 of 7819
          id: cord-328200-96tirrck
      author: Llorente-Parrado, C.
       title: Modelo de evaluación del plan de respuesta frente a la pandemia de COVID-19 en un hospital de tercer nivel
        date: 2020-10-10
       words: 2803
      flesch: 30
     summary: Agradecimientos: a los referentes de las áreas asistenciales y no asistenciales implicados, de la Dirección del Hospital, de los servicios de Medicina Preventiva y Epidemiología, Enfermedades Infecciosas y Salud Laboral, del área de Calidad y de Sistemas de Información, que han participado en el proceso de revisión o que han formado parte de los equipos auditores o de autoevaluación de los estándares del modelo. Creemos, por estos motivos, que la libre difusión tanto de este modelo y de su metodología de evaluación, como de otras iniciativas similares, bajo premisas de rigor científico-técnico e independencia y promoviendo la participación de los centros, instituciones o sociedades científicas implicadas que lo deseen, puede ser un paso relevante en aras de facilitar la consecución de esta estrategia.
    keywords: atención; con; covid-19; del; estándares; evaluación; hospital; las; los; mediante; mejora; modelo; para; por; que; una; áreas
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        item: #5710 of 7819
          id: cord-328214-2azb8789
      author: Piper-Vallillo, Andrew J.
       title: COVID-19 Infection in a Lung Cancer Patient Population: Incidence, Presentation and Alternative Diagnostic Considerations
        date: 2020-11-12
       words: 4122
      flesch: 37
     summary: COVID-19 positive patients (n = 24) were predominantly current or former smokers (87%), white (84%) and older (median age 75 years , range 57-87) Findings from larger cohorts, such as the CCC19 consortium, have also indicated age and poor PS are risk factors for mortality/poor outcomes in COVID-19 positive oncology patients.
    keywords: cancer; covid-19; infection; lung; patients; population; testing; therapy
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        item: #5711 of 7819
          id: cord-328220-toeq4xq0
      author: Smith, Kelly
       title: Practical Considerations in Prevention and Treatment of Venous Thromboembolism in Hospitalized Patients with COVID-19
        date: 2020-07-06
       words: 3213
      flesch: 34
     summary: Understanding of these abnormalities is continually evolving, but these conditions may pose a risk to COVID-19 patients beyond the risk typically seen in critically ill patients. 3, 4 Poissy et al 5 reported an increased incidence of pulmonary embolism (PE) amongst COVID-19 patients admitted to an intensive care unit.
    keywords: anticoagulation; covid-19; patients; prophylaxis; risk; therapy; tier; vte
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        item: #5712 of 7819
          id: cord-328267-tk0zc8il
      author: Liu, Qiao
       title: Collateral Impact of the Covid-19 Pandemic on Tuberculosis Control in Jiangsu Province, China
        date: 2020-08-28
       words: 1668
      flesch: 43
     summary: Tuberculosis treatment outcomes and diagnostic screening for MDR among tuberculosis patients was also reduced in 2020 indicating that health care access may have reduced or health professionals may have been unavailable in dealing with tuberculosis control after being redirected to Covid-19 control efforts. Our analysis suggests that collateral effects of the Covid-19 pandemic on tuberculosis control are substantial, with a reduction of 36%-52% in tuberculosis notifications in 2020 compared to 2015-2019.
    keywords: china; control; covid-19; tuberculosis
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        item: #5713 of 7819
          id: cord-328289-3h3kmjlz
      author: Iadecola, Costantino
       title: Effects of COVID-19 on the nervous system
        date: 2020-08-19
       words: 6543
      flesch: 28
     summary: Furthermore, several autopsy series have revealed a notable lack of immune cell infiltration (Kantonen et al., 2020; Reichard et al., 2020; Solomon et al., 2020) . Consistent with hypoxic brain injury, autopsy studies in COVID-19 have shown neuronal damage in brain regions most vulnerable to hypoxia, including neocortex, hippocampus and cerebellum (Kantonen et al., 2020; Reichard et al., 2020; Solomon et al., 2020) .
    keywords: acute; brain; cells; covid-19; disease; encephalitis; entry; et al; evidence; human; infection; manifestations; patients; sars; system; virus
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        item: #5714 of 7819
          id: cord-328307-378cfb23
      author: Shirazi, Samira
       title: Sudden cardiac death in COVID-19 patients, a report of three cases
        date: 2020-07-03
       words: 1985
      flesch: 47
     summary: Clinical features of patients infected with 2019 novel coronavirus in Wuhan • First report of COVID-19 in Lancet Clinical characteristics of coronavirus disease 2019 in China Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China • First report of COVID-19 in JAMA From SARS to MERS, thrusting coronaviruses into the spotlight Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study • First report of complete heart block from our institution New clinical experiences and evaluation of clinical and paraclinical features of deceased patients with COVID-19 infection referred to Shahid Mostafa Khomeini Hospital of Ilam • Introduces a hypothesis that cytokine storm may induce QT prolongation and torsades de pointes Association of cardiovascular manifestations with in-hospital outcomes in patients with COVID-19: a hospital staff data. key: cord-328307-378cfb23 authors: Shirazi, Samira; Mami, Sanaz; Mohtadi, Negar; Ghaysouri, Abas; Tavan, Hamed; Nazari, Ali; Kokhazadeh, Taleb; Mollazadeh, Reza title: Sudden cardiac death in COVID-19 patients, a report of three cases date: 2020-07-03 journal:
    keywords: covid-19; death; hospital; patients
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        item: #5715 of 7819
          id: cord-328319-vsyu5y45
      author: Maracaja, Luiz
       title: How 3D Printing Can Prevent Spread of COVID-19 Among Healthcare Professionals During Times of Critical Shortage of Protective Personal Equipment
        date: 2020-04-13
       words: 1197
      flesch: 52
     summary: 6 These measures are inconceivable regarding healthcare provider safety, and place each subsequent patient with whom the under-protected provider interfaces at considerable risk. The current design is optimized for stereolithography 3D printing process, and would likely require different orientation on the building platform for fused deposition modeling or other 3D printing processes.
    keywords: covid-19; healthcare; printing
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        item: #5716 of 7819
          id: cord-328321-7e37hhia
      author: Olapoju, Olabisi Michael
       title: Estimating transportation role in pandemic diffusion in Nigeria: A consideration of 1918-19 influenza and COVID-19 pandemics
        date: 2020-07-28
       words: 2919
      flesch: 45
     summary: The study notes that seaports and railways, being the emerging transportation modes in the country were significant to the importation and local diffusion of 1918-19 influenza, respectively, while air transport is significant to the importation of the current COVID-19 pandemic. Assessment of 1918-19 influenza and COVID-19 revealed that water transport (ocean and inland waterways) and air transport played significant gateway roles in the importation of the two pandemics.
    keywords: covid-19; diffusion; epidemic; influenza; nigeria; spread; transport
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        item: #5717 of 7819
          id: cord-328352-l1q4uvxl
      author: Borlongan, Mia C.
       title: The Disillusioned Comfort with COVID-19 and the Potential of Convalescent Plasma and Cell Therapy
        date: 2020-08-25
       words: 3239
      flesch: 33
     summary: The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory metaanalysis Version 2 Treatment with convalescent plasma for COVID-19 patients in Wuhan Effectiveness of convalescent plasma therapy in severe COVID-19 patients Treatment of 5 critically ill patients with COVID-19 with convalescent plasma Effect of convalescent plasma therapy on viral shedding and survival in covid-19 patients Use of Convalescent plasma therapy in two covid-19 patients with acute respiratory distress syndrome in Korea Active therapy with passive immunotherapy may be effective in the fight against Covid-19 Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a rapid review SARS-CoV-2 inflammatory syndrome. The still limited evidence but massively accumulating interest in the safety and efficacy of convalescent plasma treatments may provide the basis for compassionate use of these therapies for COVID-19 in the United States.
    keywords: convalescent; convalescent plasma; covid-19; flu; patients; plasma; treatment; virus
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        item: #5718 of 7819
          id: cord-328376-hxl3xfyl
      author: Giordano, Arturo
       title: Management of Structural Heart Disease and Acute Coronary Syndromes in the COVID-19 Pandemic
        date: 2020-06-10
       words: 1569
      flesch: 29
     summary: First, the concept of creating or adapting some hospitals to the care of COVID-19 patients only is reasonable and appropriate. Similarly, safe and high-quality management of SHD and ACS in the COVID-19 era requires careful planning and centralization of cases and procedures, using dedicated catheterization laboratories for suspected, probable, or confirmed COVID-19 patients.
    keywords: acs; covid-19; patients; shd
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        item: #5719 of 7819
          id: cord-328384-jzfr2t3p
      author: Mudatsir, Mudatsir
       title: Predictors of COVID-19 severity: a systematic review and meta-analysis
        date: 2020-09-09
       words: 4577
      flesch: 37
     summary: Furthermore, pulmonary embolism and deep vein thrombosis were also observed in patients with severe COVID-19 73, 74 , which suggests that D-dimer might play a prominent role in governing the severity of COVID-19 patients. Publisher Full Text Pathological findings of COVID-19 associated with acute respiratory distress syndrome The Clinical Manifestations and Chest Computed Tomography Findings of Coronavirus Disease 2019 (COVID-19) Patients in China: A Proportion Meta-Analysis Laboratory findings of COVID-19: a systematic review and meta-analysis Predictive symptoms and comorbidities for severe COVID-19 and intensive care unit admission: a systematic review and meta-analysis PubMed Abstract | Publisher Full Text | Free Full Text COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis Symptom Duration and Risk Factors for Delayed Return to Usual Health Among Outpatients with COVID-19 in a Multistate Health Care Systems Network -United States Predictors of COVID-19 severity: a systematic review and meta-analysis.
    keywords: analysis; covid-19; data; disease; levels; meta; patients; review; risk; studies; study
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        item: #5720 of 7819
          id: cord-328395-2cakgmsj
      author: Oxford, Alexandra E.
       title: Endothelial Cell Contributions to COVID-19
        date: 2020-09-25
       words: 6719
      flesch: 35
     summary: In addition, endothelial cell infection promotes the formation of thrombus associated with an elevated neutrophil count This review will focus on the concept of endothelial cell infection and dysfunction as an active driver of COVID-19, which begins as a respiratory illness, with vascular pathology contributing significantly to the most negative patient outcomes.
    keywords: ace2; cell; coronavirus; cov-2; covid-19; cytokines; disease; endothelial; human; infection; patients; protein; receptor; sars; treatment
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        item: #5721 of 7819
          id: cord-328396-p2gvpe8i
      author: Kaur, Savneet
       title: The Enigma of Endothelium in COVID-19
        date: 2020-08-04
       words: 4441
      flesch: 30
     summary: Lung pathology from COVID-19 patients has depicted that along with pulmonary type 2 alveolar epithelial cells, endothelial cells in the systemic venules are also desquamated and an inflammatory reaction is present in blood vessel walls (vasculitis), suggestive of intense vascular reactions (Ding et al., 2003) . Lung autopsies from COVID-19 patients also show massive neutrophil infiltration in pulmonary capillaries, acute capillaritis and extravasation of neutrophils into the alveolar space (Fox et al., 2020; Liu et al., 2020) .
    keywords: cells; cov-2; covid-19; endothelial; et al; injury; patients; pulmonary; sars
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        item: #5722 of 7819
          id: cord-328409-px92ff89
      author: Hornuss, Daniel
       title: COVID-19-assoziierte Pneumonie trotz persistierend negativen PCR-Tests aus oropharyngealen Abstrichen
        date: 2020-05-13
       words: 1588
      flesch: 34
     summary: Aufgrund der geringen Invasivität und der einfachen Durchführung ist die PCR-Analyse aus tiefen Rachen-oder Nasenabstrichen weiterhin die diagnostische Testmethode der ersten Wahl, insbesondere im Rahmen von Screening-Untersuchungen. Folgerung Die Kasuistik beschreibt einen Fall von COVID-19, bei dem trotz typischer klinischer Symptomatik sowie typischen radiologischen und laborchemischen Befunden ein Virusnachweis in mehrfach korrekt durchgeführten tiefen Rachenabstrichen nicht möglich war.
    keywords: analysis; bei; cov-2; covid-19; der; die; findings; patient; pcr; sars; und
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        item: #5723 of 7819
          id: cord-328455-kg2pg8y2
      author: Wong, S.-C.
       title: Is it possible to achieve 100 percent hand hygiene compliance during the COVID-19 pandemic?
        date: 2020-05-15
       words: 574
      flesch: 43
     summary: World Health Organization Escalating infection control response to the rapidly evolving epidemiology of the Coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in Hong Kong Impact of observing hand hygiene in practice and research: a methodological reconsideration Infection control challenge in setting up a temporary test center at the international airport for rapid diagnosis of coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 Absence of nosocomial transmission of coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in the pre-pandemic phase in Hong Kong Hand hygiene and the novel coronavirus pandemic: The role of healthcare workers Evidence supporting transmission of severe acute respiratory syndrome coronavirus 2 while presymptomatic or asymptomatic Directly observed hand hygienefrom healthcare workers to patients Hand hygiene compliance among healthcare workers in two paediatric units before and during COVID-19 pandemic All authors report no conflicts of interest relevant to this article. key: cord-328455-kg2pg8y2 authors: Wong, S.-C.; AuYeung, C.H.-Y.; Lam, G.K.-M.; Leung, E.Y.-L.; Chan, V.W.-M.; Yuen, K.-Y.; Cheng, V.C.-C. title: Is it possible to achieve 100 percent hand hygiene compliance during the COVID-19 pandemic? date: 2020-05-15 journal: J Hosp Infect DOI: 10.1016/j.jhin.2020.05.016 sha: doc_id: 328455 cord_uid: kg2pg8y2 nan enforced the practice of the WHO my five moments for hand hygiene, together with our institutionally-promoted 6 th moment -hand hygiene before touching your mucous membrane.
    keywords: hand; hygiene
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        item: #5724 of 7819
          id: cord-328484-4iptwc3n
      author: Li, Tao
       title: Clinical Characteristics of 312 Hospitalized Older Patients with COVID-19 in Wuhan, China
        date: 2020-07-15
       words: 3082
      flesch: 46
     summary: High levels of d-dimer had a reported association with pneumonia severity in emergency department, which also applied to older COVID-19 patients. But substantial numbers of severe episodes occur in older patients.
    keywords: cases; clinical; coronavirus; covid-19; patients; study
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        item: #5725 of 7819
          id: cord-328487-glwslgjy
      author: Iannaccone, Sandro
       title: ROLE OF REHABILITATION DEPARTMENT FOR ADULT COVID-19 PATIENTS: THE EXPERIENCE OF THE SAN RAFFAELE HOSPITAL OF MILAN
        date: 2020-06-04
       words: 1954
      flesch: 31
     summary: glwslgjy Abstract The rapid evolution of the health emergency linked to the spread of SARS-CoV-2 requires specifications for the rehabilitative management of COVID-19 patients. The symptomatic evolution of COVID-19 patients is characterized by two phases: an acute phase in which respiratory symptoms prevail, and a post-acute phase in which patients can show symptoms related to prolonged immobilization, to previous and current respiratory dysfunctions as well as cognitive and emotional disorders.
    keywords: care; covid-19; hospital; patients; rehabilitation
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        item: #5726 of 7819
          id: cord-328548-5kjq9xqs
      author: Oliveira J. e Silva, Lucas
       title: Flexibilization of Science, Cognitive Biases, and the COVID-19 Pandemic
        date: 2020-08-27
       words: 1463
      flesch: 38
     summary: Despite being arguably the lowest quality of scientific proof, there are several reasons to believe that anecdotal evidence, in particular, may be accorded more credence than such evidence truly merits. The term flexibilization here refers to a loosening of methodological standards and the development of low-quality studies, leading to the creation of unreliable data and, later in the cycle, of anecdotal evidence.
    keywords: covid-19; evidence; quality; spin
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        item: #5727 of 7819
          id: cord-328556-sop1yjv7
      author: Carrion, D M
       title: Evaluación de las Tendencias y Presentación Clínica de Pacientes con Cólico Nefrítico que acuden al Servicio de Urgencias Durante la Era Pandémica del COVID-19
        date: 2020-09-07
       words: 2744
      flesch: 44
     summary: Además, no se observaron diferencias significativas en cuanto a la duración de la estancia, el requerimiento de ingreso al servicio de urología y el tipo de tratamiento (colocación de stent ureteral vs inserción de nefrostomía vs TME) (tabla 2). Otra explicación podría ser que los pacientes se comunicaban telefónicamente con los servicios médicos de emergencia y, debido a la sobrecarga de los servicios de ambulancia y urgencias, se les aconsejaba quedarse en casa con analgésicos de venta libre, sólo acudiendo a urgencias en caso de fiebre o dolor incontrolado
    keywords: alarma; con; covid-19; del; estado; grupo; las; los; pacientes; por; que; servicio; urgencias
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        item: #5728 of 7819
          id: cord-328562-g5i838b3
      author: Niles, Meredith T.
       title: The Early Food Insecurity Impacts of COVID-19
        date: 2020-07-15
       words: 5003
      flesch: 40
     summary: [CrossRef] 2. United Nations Food and Agriculture Organization United Nations Food and Agriculture Organization Household Food Security in the United States Incremental health care costs associated with food insecurity and chronic conditions among older adults Food Insecurity and Health Care Expenditures in the United States Food insecurity and health outcomes Food insecurity status and mortality among adults in Ontario Association between household food insecurity and annual health care costs Food insecurity, healthcare utilization, and high cost: A longitudinal cohort study Prevalence of US Food Insecurity Is Related to Changes in Unemployment, Inflation, and the Price of Food Unemployment and household food hardship in the economic recession United States Department of Labor. Screening for food insecurity and providing resources now may reduce short-and long-term consequences, including the potential long-term impacts on child health outcomes associated with the duration of household food insecurity [35] and higher health care expenditures associated with food insecurity [9] .
    keywords: access; assistance; covid-19; food; households; insecurity; programs
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        item: #5729 of 7819
          id: cord-328569-1lx3fkv3
      author: Bagate, François
       title: Rescue therapy with inhaled nitric oxide and almitrine in COVID-19 patients with severe acute respiratory distress syndrome
        date: 2020-11-04
       words: 3769
      flesch: 44
     summary: During the first SARS-CoV outbreak in 2004, a pilot study reported the efficacy of iNO in a limited series of severe patients, with reversal of pulmonary hypertension, improved hypoxemia and shortened duration of mechanical ventilation [20] . The NO Almitrine Study Group Inhaled nitric oxide and vasoconstrictors in acute respiratory distress syndrome Additive effect on gas exchange of inhaled nitric oxide and intravenous almitrine bismesylate in the adult respiratory distress syndrome Acute respiratory distress syndrome: the Berlin Definition Formal guidelines: management of acute respiratory distress syndrome Efficacy of prone position in acute respiratory distress syndrome patients: A pathophysiology-based review Potential for lung recruitment estimated by the recruitment-toinflation ratio in acute respiratory distress syndrome a clinical trial Prevalence and prognosis of cor pulmonale during protective ventilation for acute respiratory distress syndrome Prevalence and prognosis of shunting across patent foramen ovale during acute respiratory distress syndrome The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure.
    keywords: acute; almitrine; ards; covid-19; distress; ino; patients; pulmonary; study; syndrome
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        item: #5730 of 7819
          id: cord-328601-gi6rr2np
      author: Degiorgio, Sophie
       title: COVID-19 related acute decline in paediatric admissions in Malta, a population-based study
        date: 2020-11-12
       words: 1971
      flesch: 42
     summary: This study has demonstrated a significant drop in paediatric admissions in Malta between 2019 and 2020, which negatively correlated with Malta's first wave of COVID-19 cases. key: cord-328601-gi6rr2np authors: Degiorgio, Sophie; Grech, Neil; Dimech, Yana Marie; Xuereb, John; Grech, Victor title: COVID-19 related acute decline in paediatric admissions in Malta, a population-based study date: 2020-11-12 journal:
    keywords: admissions; cases; covid-19; paediatric; pandemic
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        item: #5731 of 7819
          id: cord-328607-lzai90zq
      author: Augoustides, John G.
       title: Cardiovascular Consequences and Considerations of Coronavirus Infection – Perspectives for the Cardiothoracic Anesthesiologist and Intensivist During the Coronavirus Crisis
        date: 2020-04-09
       words: 2076
      flesch: 29
     summary: Cardiovascular and Thoracic Section, Department of Anesthesiology and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA Clinical characteristics of coronavirus disease 2019 in China Clinical features of patients with 2019 novel coronavirus in Wuhan, China Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: A single-centered, retrospective, observational study Outbreak of a new coronavirus: What anaesthetists should know Anesthetic management of patients undergoing aortic dissection repair with suspected severe acute respiratory syndrome coronavirus-2 infection Perioperative echocardiography: Key considerations during the coronavirus pandemic Protecting high-risk cardiac patients during the COVID-19 outbreak Extracorporeal membrane oxygenation À crucial considerations during the coronavirus crisis Guidance document: Extracorporeal membrane oxygenation for COVID-19 patients with severe cardiopulmonary failure Anesthetic management of patients with suspected or confirmed 2019 novel coronavirus infection during emergency procedure Clinical management of severe acute respiratory infection when novel coronavirus (2019-nCoV) infection is suspected -interim guidance Cardiovascular considerations for patients, health care workers, and health systems during the coronavirus disease 2019 (COVID-19) pandemic COVID-19 infection À implications for perioperative and critical care physicians Evidence from a meta-analysis Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19) Potential effects of coronaviruses on the cardiovascular system: A review Viral myocarditis À incidence, diagnosis and management Cardiovascular magnetic resonance in myocarditis: A JACC white paper Catheterization laboratory considerations during the coronavirus-19 (COVID-19) pandemic: From ACC's Interventional Council and SCAI CSC expert consensus on principles of clinical management of patients with severe emergent cardiovascular disease during the COVID-19 epidemic Coronavirus disease 2019 (COVID-19) and cardiovascular disease SARS Àcoronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS COVID-19 and the cardiovascular system Angiotensin II for the treatment of COVID-19-related vasodilatory shock Coronaviruses and the cardiovascular system: Acute and long-term implications SARS-CoV2: Should inhibitors of the renin-angiotensin system be withdrawn in patients with COVID-19? Inflammation and thrombosis: [1] [2] [3] [4] In the cohort of patients with severe COVID-19, the risks of admission to an intensive care unit are high owing to critical conditions such as acute respiratory distress syndrome, cardiovascular collapse, and acute renal failure.
    keywords: angiotensin; coronavirus; covid-19; management; myocarditis; patients
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        item: #5732 of 7819
          id: cord-328640-4g7revha
      author: Douedi, Steven
       title: Novel coronavirus 2019 (COVID-19): A case report and review of treatments
        date: 2020-05-08
       words: 2282
      flesch: 44
     summary: Further studies and clinical trials are required to fully understand the role of remdesivir and other medications in COVID-19 infected patients. A chest X-ray ( Fig. 1 ) was performed showing bilateral opacities throughout the lung fields with predominance of the lower lung lobes she was admitted for possible pneumonia with isolation precautions for suspected COVID-19 and was started on oxygen via nasal cannula and on 1-gram ceftazidime intravenously every 8 hours and 500 mg azithromycin orally daily.
    keywords: coronavirus; covid-19; day; hydroxychloroquine; patient; treatment
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        item: #5733 of 7819
          id: cord-328645-twl80ql1
      author: Stickley, Andrew
       title: Loneliness and COVID-19 preventive behaviours among Japanese adults
        date: 2020-09-03
       words: 3859
      flesch: 43
     summary: key: cord-328645-twl80ql1 authors: Stickley, Andrew; Matsubayashi, Tetsuya; Ueda, Michiko title: Loneliness and COVID-19 preventive behaviours among Japanese adults date: 2020-09-03 journal: J Public Health (Oxf) DOI: 10.1093/pubmed/fdaa151 sha: doc_id: 328645 cord_uid: twl80ql1 BACKGROUND: There is some evidence that loneliness may be linked to poorer health behaviours. Despite this, there has been little research to date on the relationship between loneliness and COVID-19 preventive behaviours.
    keywords: behaviours; covid-19; health; loneliness; measures; pandemic; study
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        item: #5734 of 7819
          id: cord-328646-msut5gyc
      author: Brown, Amy
       title: Experiences of breastfeeding during COVID‐19: Lessons for future practical and emotional support
        date: 2020-09-23
       words: 8813
      flesch: 50
     summary: Maternal & Child Nutrition When separation is not the answer: Breastfeeding mothers and infants affected by COVID-19. Leeds: Health and Social Care Information Centre Support for healthy breastfeeding mothers with healthy term babies Analysis of death registrations not involving coronavirus (COVID-19) Impact of the Baby-friendly Hospital Initiative on breastfeeding and child health outcomes: A systematic review Separating mothers with COVID-19 from their newborns does more harm than good.
    keywords: baby; birth; breastfeeding; covid-19; experience; health; lockdown; mothers; pandemic; participants; support; women
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        item: #5735 of 7819
          id: cord-328657-rlrs7spv
      author: Park, Jay J H
       title: Clinical trials of disease stages in COVID 19: complicated and often misinterpreted
        date: 2020-08-20
       words: 882
      flesch: 23
     summary: Broadly, COVID-19 clinical trials target at least five stages of the disease process (appendix): pre-exposure prophylaxis, post-exposure prophylaxis, outpatient treatment, hospital admission, and late-stage critical care (admission to an intensive care unit). key: cord-328657-rlrs7spv authors: Park, Jay J H; Decloedt, Eric H; Rayner, Craig R; Cotton, Mark; Mills, Edward J title: Clinical trials of disease stages in COVID 19: complicated and often misinterpreted date: 2020-08-20 journal: Lancet Glob Health DOI: 10.1016/s2214-109x(20)30365-x sha: doc_id: 328657 cord_uid: rlrs7spv nan As of July 28, 2020, 1840 clinical trials were registered globally, with 1001 clinical trials recruiting patients for COVID-19 management.
    keywords: covid-19; patients; trials
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        item: #5736 of 7819
          id: cord-328667-r5w09lb6
      author: Schwartz, David A
       title: The Effects of Pregnancy on Women with COVID-19: Maternal and Infant Outcomes
        date: 2020-05-11
       words: 1520
      flesch: 38
     summary: Africa, DRC Équateur and DR.C Kivu: Four years of excluding pregnant and lactating women and their infants from immunization Viral infection, proliferation and hyperplasia of Hofbauer cells and absence of inflammation characterize the placental pathology of fetuses with congenital Zika virus infection An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: Maternal coronavirus infections and pregnancy outcomes Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of New York City hospitals Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study Infections in pregnancy with COVID-19 and other respiratory RNA virus diseases are rarely, if ever, transmitted to the fetus: In particular, this has been especially true for pregnant women, who fear not only for themselves but often even more so for their unborn infants.
    keywords: covid-19; disease; infection; women
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        item: #5737 of 7819
          id: cord-328687-clr1e9p6
      author: Zhou, Fuling
       title: Tracing asymptomatic SARS-CoV-2 carriers among 3674 hospital staff:a cross-sectional survey
        date: 2020-09-15
       words: 3722
      flesch: 40
     summary: Thereafter, asymptomatic staff were re-examined weekly for 3 weeks until April 16, 2020. Our hospital had completed COVID-19 screening of 3674 staff without clinical symptoms, the results showed the proportion of asymptomatic infected staff was 0.76%.
    keywords: asymptomatic; cov-2; covid-19; hospital; igg; igm; sars; staff; test
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        item: #5738 of 7819
          id: cord-328693-xf2w570s
      author: Lee, Delice Weishan
       title: Intubation outside of the operating room: new challenges and opportunities in COVID-19 era
        date: 2020-06-29
       words: 2445
      flesch: 40
     summary: Several professional societies have formulated guidelines on airway management COVID-19 suspect and proven patients. Airway management in patients outside the operating room is associated with increased difficulties and risks, and the setting of the COVID-19 global pandemic adds another layer of complexity.
    keywords: airway; covid-19; intubation; management; operating; patients; room
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        item: #5739 of 7819
          id: cord-328696-ydhgzkzv
      author: Caro-Dominguez, Pablo
       title: Thoracic imaging of coronavirus disease 2019 (COVID-19) in children: a series of 91 cases
        date: 2020-08-04
       words: 4594
      flesch: 42
     summary: Table 3 summarizes chest CT findings in 24 children with confirmed COVID-19. Chest imaging findings in children younger than 18 years old who tested positive on polymerase chain reaction testing for SARS-CoV-2 were included.
    keywords: chest; children; covid-19; findings; glass; ground; imaging; lung; opacities
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        item: #5740 of 7819
          id: cord-328698-eeg1k5a6
      author: Detoc, Maëlle
       title: Intention to participate in a COVID-19 vaccine clinical trial and to get vaccinated against COVID-19 in France during the pandemic
        date: 2020-09-17
       words: 2525
      flesch: 44
     summary: Vaccine hesitancy may also have an impact on recruitment in COVID-19 vaccine clinical trial [7] . The impact of the current pandemic on the intention to participate in a COVID-19 vaccine clinical trial and on the intention to get vaccinated against COVID-19 vaccine is not obvious.
    keywords: covid-19; healthcare; hesitancy; trial; vaccine
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        item: #5741 of 7819
          id: cord-328718-j9p7ahl8
      author: Goldust, Mohamad
       title: Skin cancer and COVID‐19
        date: 2020-07-23
       words: 740
      flesch: 50
     summary: Due to minimal availability of public transport and doctors in regular clinics, several skin cancer patients are going undiagnosed, leading to delayed diagnosis resulting in worsening of its grade and prognosis. 10 Face-to-face consultations, if needed, can be decided on case to case basis after the teleconsultation, For immunosuppressed cancer patients, a separate ward with a distinct set of doctors can be used who do not come in contact with COVID-patients.
    keywords: cancer; covid-19; patients
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        item: #5742 of 7819
          id: cord-328747-bf687r6j
      author: St‐Denis, Xavier
       title: Sociodemographic Determinants of Occupational Risks of Exposure to COVID‐19 in Canada
        date: 2020-07-13
       words: 8972
      flesch: 36
     summary: I find meaningful differences in occupational risk scores by education. In order to distinguish the net role of each variable in driving occupational exposure risk differences across the labor force, I provide estimates from multivariate analysis (ordinary least square regressions) in Table 5 .
    keywords: covid-19; data; differences; diseases; exposure; health; infections; occupations; proximity; results; risk; score; workers
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        item: #5743 of 7819
          id: cord-328786-gkd9xcxa
      author: Mohammad, Laila Malani
       title: Necessity of brain imaging in COVID-19 infected patients presenting with acute neurological deficits
        date: 2020-08-13
       words: 1083
      flesch: 35
     summary: These cases highlight the importance of early head imaging in COVID-19 patients with a poor neurological exam. According to a recent review of the stroke hospitalizations in a major center in New York, while the overall reported rates of strokes in COVID-19 patients were low, this patient population presenting with CVAs tended be younger and more severe compared to non-COVID patients, as seen in our two cases.
    keywords: covid-19; exam; patients
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        item: #5744 of 7819
          id: cord-328810-ifovibzi
      author: Drefahl, Sven
       title: A population-based cohort study of socio-demographic risk factors for COVID-19 deaths in Sweden
        date: 2020-10-09
       words: 4399
      flesch: 44
     summary: In response to this call, the present study examines sociodemographic risk factors of COVID-19 mortality in Sweden. While Sweden has experienced relatively high levels of COVID-19 mortality per capita 1 , its experience may provide invaluable insight for other countries to prepare for upcoming developments.
    keywords: age; covid-19; data; death; mortality; risk; sweden
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        item: #5745 of 7819
          id: cord-328814-s3963anw
      author: XU, Jing
       title: Exploration on the feasibility of moxibustion in prevention and treatment of COVID-19 from the perspective of modern medical mechanism
        date: 2020-06-11
       words: 3457
      flesch: 40
     summary: Feasibility of yiqi xuanbi decoction in treating pulmonary fibrosis after new crown pneumonia Effects of Moxibustion of Feishu (BL13) and Gaohuangshu (BL43) on expression of E-cad Gene in lung epithelial cells in BLMA5-induced pulmonary fibrosis rats Regulation of E-cad, α-SMA and vimentin through moxibustion at Feishu and Gaohuangshu of pulmonary fibrosis rats Combined with Qiangli Zhike Capsule (强力止咳宁胶囊) on Chronic Bronchitis Clinical observation of yang-supplementing fire moxibustion for chronic obstructive pulmonary disease in stable stage Contribution of physicians in the south of the Five Ridges in acupuncture and moxibustion treatment of plague and cholera Clinical observation of moxibustion in the treatment of 79 cases of epidemic hemorrhagic fever Observation on the effect of moxibustion on renal function of epidemic hemorrhagic fever 20 cases of condyloma acuminatum treated with moxibustion Retrospective analysis of Mr. Xie Xiliang's medical records accumulated in 30 years on direct moxibustion for treating hepatitis B Clinical observation of treating refractory pulmonary tuberculosis with garlic moxibustion A pneumonia outbreak associated with a new coronavirus of probable bat origin Nine cases of the chronic stage of SARS treated by moxibustion Clinical observation of heat-sensitive moxibustion treatment for coronavirus disease Discussion on the effect pathways of preventing and treating coronavirus disease 2019 by acupuncture and moxibustion from the regulation of immune inflammatory response On TCM diagnosis and treatment program of Coronavirus Disease 2019 in Hunan province by national TCM Master XIONG Jibo Discussion on traditional Chinese medicine prevention and treatment strategies of Coronavirus Disease 2019 (COVID-19) from the perspective of cold-dampness pestilence The role of immunological testing and intervention in reproductive medicine: A fertile collaboration? Analysis of novel coronavirus pneumonia related blood test indexes in 80 cases Clinical characteristics and laboratory results of 3 886 patients with fever and cough Therapeutic effect of ginger warming and moxibustion on children's cough variant asthma and its influence to on immune function Regulation effect of moxibustion with small moxa-cone about the size of a wheat grain at zusanli point on cellular immune function in elderly bedridden patients Clinical study on the effect of Du-moxibustion therapy on the symptom and levels of serum supplement C3 and C4 in yang-deficiency subjects The effect of moxibustion shenque point on immune function of digestive tract cancer patients undergoing chemotherapy Effect of moxibustion on survival status and nutritional metabolic factor in tumor-bearing rats with gastric cancer Effect of solar-term moxibustion on hemorheology and immune function in patients with subhealth status of yang deficiency Molecular pathways in virus-induced cytokine production Therapeutic strategies for COVID-19 based on its pathophysiological mechanisms Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Effect of electroacupuncture stimulation of Feishu (BL 13) on lung index, serum and lung IL-10 and and TNF-α levels in mice with viral pneumonia Effect of mild moxibustion on bacterial infection and inflammation in mice and related autophagy mechanism Effect of moxibustion on body weight and peripheral and cerebral cortical IL-6 and IL-10 levels in fatigue rats Mechanism study on NIK/NF-κB/VEGF pathway, anti-inflammation and analgesia in RA treated with moxibustion Effect of moxibustion on TGF-β1, HIF-1α and VEGF levels in patients with rheumatoid arthritis (RA) Effects of moxa-moxibustion plus infrared illumination on community acquired pneumonia and immune function Thinking of the effect of integrated Chinese and western medicine on COVID-19 Dynamic changes of serum SARS-coronavirus IgG, pulmonary function and radiography in patients recovering from SARS after hospital discharge
    keywords: body; covid-19; disease; effect; function; moxibustion; patients; treatment; yang
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        item: #5746 of 7819
          id: cord-328826-guqc5866
      author: Wissel, Benjamin D
       title: An Interactive Online Dashboard for Tracking COVID-19 in U.S. Counties, Cities, and States in Real Time
        date: 2020-04-25
       words: 1807
      flesch: 54
     summary: It displays COVID-19 data from every county and 188 metropolitan areas in the U.S. Features include rankings of the worst affected areas and auto-generating plots that depict temporal changes in testing capacity, cases, and deaths. The Centers for Disease Control and Prevention (CDC) do not publish COVID-19 data for local municipalities, so it is critical that academic resources fill this void so the public can stay informed.
    keywords: cases; county; covid-19; data; public
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        item: #5747 of 7819
          id: cord-328859-qx7kvn0u
      author: Zhu, Hongjun
       title: Transmission Dynamics and Control Methodology of COVID-19: a Modeling Study
        date: 2020-09-21
       words: 6177
      flesch: 51
     summary: Computing Asymptotic behavior and stability in epidemic models Stability analysis for a vector disease model The generalized discrete-time epidemic model with immunity: a synthesis Transmission dynamics and control of severe acute respiratory syndrome The mathematics of infectious diseases Some evolutionary stochastic processes A simple stochastic epidemic Analysis of an SEIRS epidemic model with two delays An approximate maximum likelihood estimator for chain binomial models See [14] and [25] for an extensive review of classic epidemic models.
    keywords: covid-19; epidemic; individuals; infectives; model; number; period; seir; time; wuhan
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        item: #5748 of 7819
          id: cord-328908-2004vp48
      author: Thombs, Brett D.
       title: Changes in mental health symptoms from pre-COVID-19 to COVID-19 among participants with systemic sclerosis from four countries: A scleroderma patient-centered intervention network (SPIN) cohort study
        date: 2020-10-03
       words: 2655
      flesch: 46
     summary: Our study is one of the first to report mental health symptom changes during COVID-19 in a vulnerable population with a pre-existing medical condition and the first to compare symptom changes across countries. key: cord-328908-2004vp48 authors: Thombs, Brett D.; Kwakkenbos, Linda; Henry, Richard S.; Carrier, Marie-Eve; Patten, Scott; Harb, Sami; Bourgeault, Angelica; Tao, Lydia; Bartlett, Susan J.; Mouthon, Luc; Varga, John; Benedetti, Andrea title: Changes in mental health symptoms from pre-COVID-19 to COVID-19 among participants with systemic sclerosis from four countries: A scleroderma patient-centered intervention network (SPIN) cohort study date: 2020-10-03 journal: J Psychosom Res DOI: 10.1016/j.jpsychores.2020.110262 sha: doc_id: 328908 cord_uid: 2004vp48 Introduction No studies have reported mental health symptom comparisons prior to and during COVID-19 in vulnerable medical populations.
    keywords: anxiety; covid-19; depression; health; symptoms
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        item: #5749 of 7819
          id: cord-328916-j2ztk2hk
      author: Queiroz, Maciel M.
       title: Impacts of epidemic outbreaks on supply chains: mapping a research agenda amid the COVID-19 pandemic through a structured literature review
        date: 2020-06-16
       words: 8091
      flesch: 26
     summary: The Palgrave Handbook of Humanitarian Logistics and Supply Chain Management Air transport and logistics in pandemic outbreak of influenza A (H1N1) virus A game-theoretic model of international influenza vaccination coordination Coron aviru s-and-techn ology -suppl y-chain s-How-to-resta rt-and-rebui ld?cid = other -eml-alt-mip-mck&hlkid = 1100d 1a33f ec400 eaddd db25a 2144b 77&hctky =99849 Decentralized beneficiary behavior in humanitarian supply chains: Models, performance bounds, and coordination mechanisms Analysing supply chain integration through a systematic literature review: A normative perspective How China can rebuild global supply chain resilience after COVID-19 Living with influenza: Impacts of government imposed and voluntarily selected interventions Covid 19 coronavirus: Countries compete for masks, medical supplies amid global pandemic Lessons learned: Role of influenza vaccine production, distribution, supply, and demand-What it means for the provider Challenges for the cyber-physical manufacturing enterprises of the future Distribution of medication considering information, transshipment, and clustering: Malaria in Malawi Designing robust policies under deep uncertainty for mitigating epidemics A mathematical modelling approach for managing sudden disturbances in a three-tier manufacturing supply chain Optimization of network redundancy and contingency planning in sustainable and resilient supply chain resource management under conditions of structural dynamics Integrated detection of disruption scenarios, the ripple effect dispersal and recovery paths in supply chains Systematic reviews from astronomy to zoology: Myths and misconceptions A review of the existing and emerging topics in supply chain risk management literature. Lessons from and thinking beyond the COVID-19 pandemic New flexibility drivers in manufacturing, service, and supply chain systems Coronavirus (COVID-19/SARS-CoV-2) and supply chain resilience: A research note Low-certainty-need (LCN) supply chains: A new perspective in managing disruption risks and resilience A digital supply chain twin for managing the disruptions risks and resilience in the era of Industry 4.0.
    keywords: 2020a; analysis; chain; covid-19; epidemic; et al; ivanov; literature; logistics; management; operations; outbreaks; pandemic; research; resilience; scs; supply
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        item: #5750 of 7819
          id: cord-328957-mzi8504f
      author: Lazebnik, T.
       title: The signature features of COVID-19 pandemic in a hybrid mathematical model - implications for optimal work-school lockdown policy
        date: 2020-11-04
       words: 8708
      flesch: 63
     summary: Besides, the asymptotic solution can be used to easily 515 obtain D a and D c as they accumulative sums of infected infected adults and children 516 multiplied by a factor ψ a and ψ c and do not change after the epidemic is over. ; https://doi.org/10.1101/2020.11.02.20224584 doi: medRxiv preprint In Eq (4), dIa(t) dt is the dynamical amount of infected adult individuals over time.
    keywords: adults; age; children; license; model; population; preprint; rate
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        item: #5751 of 7819
          id: cord-328987-ntu1wdzg
      author: Teng, Yi-Man
       title: Life or Livelihood? Mental Health Concerns for Quarantine Hotel Workers During the COVID-19 Pandemic
        date: 2020-09-15
       words: 2465
      flesch: 41
     summary: It is a very difficult choice for quarantine hotel employees. Thus, it is important to keep the health and safety of quarantine hotel employees, particularly the cleaners, at the center of operations.
    keywords: covid-19; employees; health; hotel; pandemic; quarantine; staff
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        item: #5752 of 7819
          id: cord-328988-q6j2njm8
      author: Tocto-Erazo, M.
       title: Lockdown, relaxation, and ACME period in COVID-19: A study of disease dynamics on Hermosillo, Sonora, Mexico
        date: 2020-08-22
       words: 4654
      flesch: 47
     summary: Table 2 : Model parameter distributions. Then, statistical analyses of different parameter scenarios, that validate the data, are presented.
    keywords: acme; covid-19; epidemic; individuals; measures; model; people; preprint; scenarios
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        item: #5753 of 7819
          id: cord-329010-n0mz098o
      author: McKee, Dwight L.
       title: Candidate drugs against SARS-CoV-2 and COVID-19
        date: 2020-04-29
       words: 5211
      flesch: 32
     summary: V. Effects on the pancreatic enzymes and experimental acute pancreatitis in rats Plasma collection using nafamostat mesilate and dipyridamole as an anticoagulant Continuous regional arterial infusion versus intravenous administration of the protease inhibitor nafamostat mesilate for predicted severe acute pancreatitis: a multicenter, randomized, open-label, phase 2 trial Identification of nafamostat as a potent inhibitor of middle east respiratory syndrome coronavirus S protein-mediated membrane fusion using the split-protein-based cell-cell fusion assay Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronoavirus Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2 ACEH/ACE2 is a novel mammalian metallocarboxypeptidase and a homologue of angiotensin-converting enzyme insensitive to ACE inhibitors, Can Hydroxychloroquine: from malaria to autoimmunity New insights into the antiviral effects of chloroquine Anti-malaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal model Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Targeting endosomal acidification by chloroquine analogs as a promising strategy for the treatment of emerging viral diseases In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) At day 21, SARS patients treated with lopinavir/ritonavir had a milder disease course in terms of diarrhea, recurrence of fever, worsening of chest radiographs and reduction of viral load, compared to a historical control group [95] .
    keywords: ace2; antiviral; cell; chloroquine; coronavirus; cov-2; covid-19; infection; lopinavir; protein; ritonavir; sars; treatment
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        item: #5754 of 7819
          id: cord-329051-gmwgb32g
      author: Kuo, C.-L.
       title: ApoE e4e4 genotype and mortality with COVID-19 in UK Biobank
        date: 2020-06-20
       words: 1576
      flesch: 43
     summary: key: cord-329051-gmwgb32g authors: Kuo, C.-L.; Pilling, L. C.; Atkins, J. L.; Masoli, J.; Delgado, J.; Kuchel, G.; Melzer, D. title: ApoE e4e4 genotype and mortality with COVID-19 in UK Biobank date: 2020-06-20 journal: nan DOI: 10.1101/2020.06.19.20134908 sha: doc_id: 329051 cord_uid: gmwgb32g We previously reported that the ApoE e4e4 genotype was associated with COVID-19 test positivity (OR=2.31, 95% CI: 1.65 to 3.24, p=1.19x10-6) in the UK Biobank (UKB) cohort, during the epidemic peak in England, from March 16 to April 26, 2020. With more COVID-19 test results (March 16 to May 31, 2020) and mortality data (to April 26, 2020) linked to UKB, we re-evaluated the ApoE e4 allele association with COVID-19 test positivity, and with all-cause mortality following test-confirmed COVID-19.
    keywords: apoe; covid-19; test
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        item: #5755 of 7819
          id: cord-329055-ftwlmi7w
      author: Costa, Klinger Vagner Teixeira da
       title: Smell and taste disorders: warning signs for SARS-CoV-2 infection()
        date: 2020-05-30
       words: 504
      flesch: 54
     summary: Loss of smell and taste in combination with other symptoms is a strong predictor of COVID-19 infection. key: cord-329055-ftwlmi7w authors: Costa, Klinger Vagner Teixeira da; Carnaúba, Aline Tenório Lins title: Smell and taste disorders: warning signs for SARS-CoV-2 infection() date: 2020-05-30 journal:
    keywords: covid-19; smell
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        item: #5756 of 7819
          id: cord-329088-tcqp8qd2
      author: Leng, C
       title: From chaos to a new norm: The Birmingham experience of restructuring the largest plastics department in the UK in response to the COVID-19 pandemic.
        date: 2020-09-20
       words: 3922
      flesch: 45
     summary: We acknowledge that the large size of our department facilitated the dramatic breadth of cover we were able to provide during the COVID-19 pandemic, but this capability is not unique to us, and the lessons we have learned can be applied by other plastic surgery departments wishing to expand their scope of practice in times of need. Plastic surgery trainees were initially on a COVID-19 ITU, and later distributed to non-COVID-19 as the first wave eased.
    keywords: covid-19; department; itu; pandemic; plastic; response; specialty; surgery; ward
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        item: #5757 of 7819
          id: cord-329096-oitxf0fp
      author: Poorolajal, Jalal
       title: Geographical Distribution of COVID-19 Cases and Deaths Worldwide
        date: 2020-09-30
       words: 648
      flesch: 60
     summary: COVID-19 disease involved almost all countries around the world. Moreover, the disease surveillance system and completeness and timeliness of cases and/or deaths reports can cause differences in disease mortality and morbidity rates in different parts of the world.
    keywords: disease
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        item: #5758 of 7819
          id: cord-329123-ytezkugu
      author: Santi, Aura Daniella
       title: Atrial fibrillation in a child with COVID-19 infection
        date: 2020-10-19
       words: 1418
      flesch: 32
     summary: 7 Monitoring for cardiovascular complications via serial troponin with early intervention is essential for multi-system inflammatory syndrome in children patients. The patient received recommended intravenous immunoglobulin treatment for multi-system inflammatory syndrome in children (100 g, weight-based maximum).
    keywords: cardiac; children; covid-19; patient
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        item: #5759 of 7819
          id: cord-329152-1ixylnny
      author: Gupta, Shaili
       title: Hospital preparedness for COVID-19 pandemic: experience from department of medicine at Veterans Affairs Connecticut Healthcare System
        date: 2020-04-24
       words: 3496
      flesch: 44
     summary: Portable forced air system was used to create such rooms in an ICU section too that was devoted to COVID-19 patient care. 4.2 ICU and on-ward policy of care was devised and revised in real-time to continue state-of-the-art management of COVID-19 patients, with a multidisciplinary team approach, involving General Medicine, Cardiology, Infectious Diseases, Infection Prevention, Pulmonary and Critical Care Medicine, and Pharmacy.
    keywords: care; clinical; covid-19; healthcare; hospital; pandemic; patients; response; rooms
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        item: #5760 of 7819
          id: cord-329193-xuxbqbsf
      author: Park, Soo-kyung
       title: Detection of SARS-CoV-2 in Fecal Samples from Patients with Asymptomatic and Mild COVID-19 in Korea
        date: 2020-06-10
       words: 3535
      flesch: 46
     summary: Although COVID-19 is characterized by fever and respiratory symptoms, some patients have no or mild symptoms. It is well established that most patients with COVID-19 have fever along with respiratory symptoms, and human-to-human transmission occurs among close contacts, mainly through respiratory droplets and direct contact.
    keywords: covid-19; patients; sars; shedding; specimens; symptoms
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        item: #5761 of 7819
          id: cord-329215-awxfetdj
      author: Carter, Chris
       title: COVID-19 Disease: invasive ventilation
        date: 2020-06-01
       words: 5520
      flesch: 40
     summary: Mechanical ventilation in the critically ill patient: international nursing perspectives Emergency Intubation outside Operating Room/Intensive Care Unit Settings: Are We Following the Recommendations for Safe Practice? Clinical guide for the management of critical care patients during the coronavirus pandemic Consensus guidelines for managing the airway in patients with COVID-19 Device or target? The monitoring of ventilated patients must include ECG, pulse oximetry and End Tidal Carbon Dioxide (EtCO 2 ).
    keywords: airway; care; circuit; complications; covid-19; ett; intubation; oxygenation; patients; pressure; ventilation; weaning
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        item: #5762 of 7819
          id: cord-329219-7mfi16rd
      author: Gisondi, P.
       title: The impact of the COVID‐19 pandemic on patients with chronic plaque psoriasis being treated with biological therapy: the Northern Italy experience
        date: 2020-05-28
       words: 1060
      flesch: 45
     summary: There is uncertainty concerning the outcome of COVID-19 infection in patients with chronic plaque psoriasis receiving biological systemic therapies. [4] [5] [6] We performed a retrospective multicentre observational study, which included patients with chronic plaque psoriasis (n = 5206) who were being treated with biological therapy, with the objective of reporting the number of patients hospitalized or who died from COVID-19 infection between 20 February 2020 and 1 April 2020.
    keywords: covid-19; deaths; patients
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        item: #5763 of 7819
          id: cord-329224-t45bedot
      author: Byrnes, Yasmeen M.
       title: Effect of the COVID-19 pandemic on medical student career perceptions: a national survey study
        date: 2020-07-24
       words: 4053
      flesch: 49
     summary: While to our knowledge there are no studies exploring SARS or MERS impact on medical student specialty choice, one post-Katrina New Orleans study found that medical students were significantly more likely to specialize in Emergency Medicine (EM) and less likely to specialize in Psychiatry in the 5 years after the hurricane than in the 5 years before [17] . Medical student specialty choice has been written about prior to the COVID-19 pandemic, and studies have suggested many factors can play a role, such as exposure to role models and core rotation experiences
    keywords: choice; covid-19; education; medical; pandemic; specialty; students; survey
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        item: #5764 of 7819
          id: cord-329253-z6okp606
      author: Levine, Ross L.
       title: COVID-19 impact on early career investigators: a call for action
        date: 2020-06-05
       words: 1599
      flesch: 36
     summary: The current landscape has the potential to result in irreparable harm to a generation of talented scientists and derail the impressive progress we have seen in cancer research in the past decade. The funding landscape for cancer research in the US context, which is likely applicable to other contexts, also presents daunting challenges.
    keywords: cancer; career; ecis; investigators; research
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        item: #5765 of 7819
          id: cord-329268-0zhabgkt
      author: Savoia, E.
       title: Factors Associated with Access and Use of PPE during COVID-19: A Cross-sectional Study of Italian Physicians
        date: 2020-05-01
       words: 3727
      flesch: 48
     summary: We then applied ordered logistic regression to the three ordinal variables access to PPE, information on PPE use, and donning and doffing ability and logistic regression to the variable risk perception. However, given the difficulties of creating 100% COVID-19 free clinics as many patients may present to a clinic in a pauci-symptomatic status, the current variation in access and knowledge about PPE use, may put at a disproportionate risk those working outside COVID-19 units.
    keywords: medrxiv; physicians; ppe; preprint; review; risk; use
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        item: #5766 of 7819
          id: cord-329292-n1aw0lyx
      author: Guven, Fadime
       title: Leptomeningeal involvement in a patient with systemic lupus erythematosus infecting by COVID-19
        date: 2020-06-10
       words: 106
      flesch: 45
     summary: key: cord-329292-n1aw0lyx authors: Guven, Fadime; Ogul, Hayri; Turgut, Asli; Tezcan, Alperen; Kantarci, Mecit title: Leptomeningeal involvement in a patient with systemic lupus erythematosus infecting by COVID-19 date: 2020-06-10 journal: Joint Bone Spine DOI: 10.1016/j.jbspin.2020.06.002 sha: doc_id: 329292 cord_uid: n1aw0lyx nan Journal Pre-proof Leptomeningeal Magnetic resonance (MR) imaging showed a few leptomeningeal micronodular lesions ( Figure 1 ). Coronavirus Disease-2019: Implication for the care and management of patients with systemic lupus erythematosus Diagnosis of the Coronavirus disease (COVID-19): rRT-PCR or CT?
    keywords: leptomeningeal
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        item: #5767 of 7819
          id: cord-329293-jlrzu0wl
      author: Ayanlade, Ayansina
       title: COVID-19 and food security in Sub-Saharan Africa: implications of lockdown during agricultural planting seasons
        date: 2020-09-14
       words: 4108
      flesch: 40
     summary: Despite the increase in rice crop production in recent years, many SSA countries still import rice and the countries majorly earn their total foreign exchange revenue from agriculture. Vulnerability of SSA is attributed to several factors including; poor health facilities in many SSA countries and low capacity for testing, timely detection and response to COVID-19 cases 1,2 .
    keywords: africa; change; climate; countries; covid-19; food; production; rice; ssa
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        item: #5768 of 7819
          id: cord-329308-ipui7lo6
      author: Lim, Soo
       title: Proper Management of People with Obesity during the COVID-19 Pandemic
        date: 2020-06-30
       words: 4617
      flesch: 32
     summary: Obesity (Silver Spring) Clinical findings of patients with coronavirus disease 2019 in Jiangsu province, China: a retrospective, multi-center study Severe obesity, increasing age and male sex are independently associated with worse in-hospital outcomes, and higher in-hospital mortality Association of higher body mass index (BMI) with severe coronavirus disease 2019 (COVID-19) in younger patients Clinical characteristics and outcomes of 112 cardiovascular disease patients infected by 2019-nCoV Covid-19 in critically ill patients in the Seattle region: case series Surgical tracheostomies in COVID-19 patients: a multidisciplinary approach and lessons learned Body mass index, weight discrimination, and psychological, behavioral, and interpersonal responses to the coronavirus pandemic MYC-induced reprogramming of glutamine catabolism supports optimal virus replication COVID-19: consider cytokine storm syndromes and immunosuppression Coagulopathy and antiphospholipid antibodies in patients with Covid-19 Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis Regular exercise enhances the immune response against microbial antigens through up-regulation of toll-like receptor signaling pathways Participation profile of adults with class III obesity Immunologic profile of excessive body weight Impact of obesity on influenza a virus pathogenesis, immune response, and evolution Obesity and COVID-19: A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury Loss of angiotensin-converting enzyme 2 accelerates maladaptive left ventricular remodeling in response to myocardial infarction Korean Society for the Study of Obesity Guideline for the Management of Obesity in Korea Angiotensin-converting enzyme 2 is an essential regulator of heart function SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2 Renin-angiotensin-aldosterone system inhibitors and risk of Covid-19 Evidence against a major role for angiotensin converting enzyme-related carboxypeptidase (ACE2) in angiotensin peptide metabolism in the human coronary circulation Elevated plasma angiotensin converting enzyme 2 activity is an independent predictor of major adverse cardiac events in patients with obstructive coronary artery disease Urinary angiotensin-converting enzyme 2 in hypertensive patients may be increased by olmesartan, an angiotensin II receptor blocker Effects of captopril related to increased levels of prostacyclin and angiotensin-(1-7) in essential hypertension SARS-CoV-2 receptor and regulator of the renin-angiotensin system: celebrating the 20th anniversary of the discovery of ACE2 Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Clinical consequences of angiotensin-converting enzyme inhibitor withdrawal in chronic heart failure: a double-blind, placebo-controlled study of quinapril: the Quinapril Heart Failure Trial Investigators Indications for ACE inhibitors in the early treatment of acute myocardial infarction: systematic overview of individual data from 100,000 patients in randomized trials Renin-angiotensin system blockers and the COVID-19 pandemic: at present there is no evidence to abandon renin-angiotensin system blockers Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein Simvastatin suppresses RANTES-mediated neutrophilia in polyinosinic-polycytidylic acid-induced pneumonia Pleiotropic effects of statins on the cardiovascular system Influenza and COPD mortality protection as pleiotropic, dose-dependent effects of statins Collateral damage of the COV-ID-19 pandemic on nutritional quality and physical activity: perspective from South Korea
    keywords: ace2; angiotensin; coronavirus; cov-2; covid-19; disease; obesity; pandemic; patients; people; risk; sars; system
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        item: #5769 of 7819
          id: cord-329312-bvnky9yr
      author: Alemany-Arrebola, Inmaculada
       title: Influence of COVID-19 on the Perception of Academic Self-Efficacy, State Anxiety, and Trait Anxiety in College Students
        date: 2020-10-09
       words: 4875
      flesch: 43
     summary: On the other hand, the perceived academic self-efficacy in the academic environment and the performance of university students are factors that are positively related. A subsequent study confirmed the influence that academic self-efficacy and emotions have on the academic success of university students.
    keywords: anxiety; covid-19; efficacy; levels; self; students; university
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        item: #5770 of 7819
          id: cord-329323-1cquorhs
      author: Ko, Jean Y
       title: Risk Factors for COVID-19-associated hospitalization: COVID-19-Associated Hospitalization Surveillance Network and Behavioral Risk Factor Surveillance System
        date: 2020-09-18
       words: 4203
      flesch: 32
     summary: Rate Ratio *Each adjusted model for underlying medical condition includes the select underlying medical condition, age, sex, and race/ethnicity underlying medical condition excludes hypertension to align with 2018 BRFSS community estimates of underlying medical conditions; the most recent year of available BRFSS data for hypertension was As of June 23, 2020, 5,715 adult COVID-19-associated hospitalizations were eligible for inclusion in our analysis; 5,416 adults had underlying medical condition data and were included as hospitalized cases for this study (Figure 1 ).
    keywords: adults; conditions; covid-19; disease; hospitalization; medical; net; risk
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        item: #5771 of 7819
          id: cord-329344-06uk5sjp
      author: Neumann-Podczaska, Agnieszka
       title: COVID 19 - Clinical Picture in the Elderly Population: A Qualitative Systematic Review
        date: 2020-07-23
       words: 5928
      flesch: 40
     summary: Description: Ground Glass Opacities (GGO) was the most commonly reported observation in radiological imaging of older COVID-19 patients. 10-18, 24-26, 28 Besides a risk for secondary infection or ARDS, older COVID-19 patients are prone to renal injury over the course of the disease.
    keywords: clinical; covid-19; data; disease; findings; patients; population; review; studies; study
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        item: #5772 of 7819
          id: cord-329350-qrxl5o1e
      author: Pan, Angelo
       title: Suggestions from Cremona, Italy - two months into the pandemic at the frontline of COVID-19 in Europe
        date: 2020-06-09
       words: 1664
      flesch: 51
     summary: Early intubation is recommended to manage COVID-19 patients (7) and very rapidly you may run out ventilators. On the HCWs' side, working with COVID-19 patients is an incredible stressful duty since it is a highly transmittable disease.
    keywords: care; covid-19; hcw; management; patients
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        item: #5773 of 7819
          id: cord-329351-g9qlo3xh
      author: Toraih, Eman A.
       title: Association of cardiac biomarkers and comorbidities with increased mortality, severity, and cardiac injury in COVID‐19 patients: A meta‐regression and Decision tree analysis
        date: 2020-06-12
       words: 1907
      flesch: 42
     summary: In addition, meta-analysis showed that COVID-19 patients who developed complications were more likely to have adverse outcomes with higher risk of mortality ( Furthermore, as depicted in Table 2 patients who received antibiotics (OR = 3.36, 95%CI = 1.66 to 6.77, p = 0.001), glucocorticoids (OR = 3.52, 95%CI = 2.51 to 4.93, p <0.001), immunoglobulins (OR = 3.41, 95%CI = 1.90 to 6.14, p <0.001), and hydroxychloroquine (OR = 6.67, 95%CI = 2.0 to 22.2, p = 0.002) had higher risk for poor prognosis. Table S1 summarizes pooled estimates for seven cardiac biomarkers, eight comorbidities, and nine secondary complications in COVID-19 patients with severe presentation compared to non-severe cohorts, who developed secondary cardiac injury versus not, ICU admitted patients versus general ward patients and survived versus expired.
    keywords: analysis; covid-19; mortality; patients
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        item: #5774 of 7819
          id: cord-329353-0pwgzeec
      author: Wambier, Carlos Gustavo
       title: Male balding as a major risk factor for severe COVID-19: a possible role for targeting androgens and transmembrane protease serine 2 to protect vulnerable individuals
        date: 2020-09-11
       words: 705
      flesch: 43
     summary: It is noteworthy that severe baldness was reported to be a better 43 predictor of test positivity than obesity, as there are many reports linking obesity to COVID-19 44 disease severity. Severe baldness, 52 the Gabrin sign (NHS=3-7), has been associated with both increased ICU admissions and 53 increased death rates.
    keywords: covid-19
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        item: #5775 of 7819
          id: cord-329363-kaw3h5xm
      author: Vardeny, Orly
       title: Applying the Lessons of Influenza to COVID-19 During a Time of Uncertainty
        date: 2020-05-26
       words: 1031
      flesch: 20
     summary: Whereas the majority of severe morbidity associated with COVID-19 has been pulmonary, reports are emerging of cardiac injury, left ventricular dysfunction, and myocarditis associated with severe COVID-19, 4 and the molecular similarities of SARS-CoV-2 and SARS-CoV make cardiac effects similar to those reported with SARS likely. In patients without known or suspected COVID-19, this includes all evidence-based therapies in cardiovascular disease, such as aspirin, statins, and β-blockers for secondary prevention in patients with coronary disease, and guideline-directed medical therapy in those with heart failure.
    keywords: covid-19; disease; influenza; sars
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        item: #5776 of 7819
          id: cord-329384-uvgwth5n
      author: Milligan, Gregory P.
       title: Recognizing Right Ventricular Dysfunction in COVID-19 Related Respiratory Illness
        date: 2020-05-11
       words: 538
      flesch: 25
     summary: Among COVID-19 patients, elevations in troponin and brain natriuretic peptide levels have been shown to be both correlative with elevations in D-dimer and predictive of mortality (3). These laboratory abnormalities may not be a coincidence as emerging autopsies on COVID-19 patients have identified small vessel pulmonary thrombosis and RV dilation (4).
    keywords: covid-19
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        item: #5777 of 7819
          id: cord-329412-pzv4dzow
      author: Massaad, Elie
       title: Social Media Data Analytics on Telehealth During the COVID-19 Pandemic
        date: 2020-04-26
       words: 1657
      flesch: 43
     summary: Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China Detection of SARS-CoV-2 in different types of clinical specimens Covid-19 and healthcare's digital revolution Digital mental health and COVID-19: using technology today to accelerate the curve on access and quality tomorrow Twitter as a tool for health research: a systematic review Natural language processing with Python: analyzing text with the natural language toolkit heatmaply: an R package for creating interactive cluster heatmaps for online publishing Social media and emergency preparedness in response to novel coronavirus US public concerns about the COVID-19 pandemic from results of a survey given via social media Addressing the COVID-19 pandemic in populations with serious mental illness Securing the safety net and protecting public health during a pandemic: medicaid's response to COVID-19 Ensuring and sustaining a pandemic workforce Mental health was the most common health-related topic that appeared in our search reflecting a high need for mental healthcare during the pandemic.
    keywords: covid-19; health; pandemic; telehealth; tweets
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        item: #5778 of 7819
          id: cord-329453-ry1diso2
      author: Hammer, Mark M.
       title: Radiologist Reporting and Operational Management for Patients with Suspected COVID-19
        date: 2020-06-11
       words: 2507
      flesch: 30
     summary: Primary outcome was percentage of COVID-19 reports using recommended terminology; secondary outcome was percentages of suspected and unsuspected patients diagnosed with COVID-19. Results Among 77,400 total reports, 1,083 suggested COVID-19 based on imaging findings; 774 (71%) of COVID-19 reports used recommended terminology.
    keywords: covid-19; findings; imaging; patients; reports
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        item: #5779 of 7819
          id: cord-329460-wl09mlk1
      author: Bozkurt, Ozan
       title: Nation‐wide analysis of the impact of Covid‐19 pandemic on daily urology practice in Turkey
        date: 2020-09-30
       words: 2268
      flesch: 38
     summary: In a detailed analysis of the three groups of centers; a significant decrease was detected in outpatients, inpatients, daily interventions and urological surgeries in tertiary referral centers and state hospitals; however the decrease was not statistically significant in private practice hospital in terms of inpatients and daily interventions ( Although the total numbers of temporary measures like nephrostomy placement (539 to 223; -58.7%) and percutaneous cystostomy (661 to 253; -61.8%) for certain instances decreased; the rate of these procedures for emergent-trauma surgeries has been found to increase during pandemic period (15% to 22.7% and 18.4% to 25.7%; respectively). Most state hospitals also turned to pandemic hospitals and did not serve for routine practice.
    keywords: centers; covid-19; hospitals; pandemic; surgeries; urology
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        item: #5780 of 7819
          id: cord-329482-haenltxn
      author: Small, Eusebius
       title: Covid-19 and Gender in LMICs: Potential Lessons from HIV Pandemic
        date: 2020-05-25
       words: 1583
      flesch: 46
     summary: Evidence from public census data COVID-19 could lead to millions of unintended pregnancies, new UN-backed data reveals Gender-Based Violence Increases Risk of HIV/AIDS for Women in Sub-Saharan Africa -Population Reference Bureau Experiences of gender-based violence among female sex workers, men who have sex with men, and transgender women in Latin America and the Caribbean: a qualitative study to inform HIV programming UK. For example, many HIV infected women will lack the essential antiretroviral therapy (ART) drugs, or pre-exposure prophylaxis (PreP) because of disruptions in the supply chain.
    keywords: covid-19; health; hiv; impact; violence; women
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        item: #5781 of 7819
          id: cord-329498-nr9k7hf2
      author: Lemke, Michael Kenneth
       title: Syndemic frameworks to understand the effects of COVID-19 on commercial driver stress, health, and safety
        date: 2020-05-23
       words: 1795
      flesch: 24
     summary: Instead, commercial driver COVID-19 research and prevention needs syndemic frameworks to holistically understand the impacts of COVID-19 on commercial driver stress, health, and safety, and to identify high-leverage preventive actions. Syndemic frameworks can provide the grounding to allow foregoing commercial driver COVID-19 research to transcend the limitations of prevailing research frameworks by contextualizing COVID-19 stressors holistically within the complex system of endemic chronic stressors and interrelated health and safety afflictions.
    keywords: covid-19; drivers; health; safety; stressors
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        item: #5782 of 7819
          id: cord-329499-jh4pbqxu
      author: Leulseged, T. W.
       title: COVID-19 in Hospitalized Ethiopian Children: Characteristics and Outcome Profile
        date: 2020-11-04
       words: 3835
      flesch: 52
     summary: Methods: A prospective cohort study was conducted among 90 consecutively admitted eligible RT-PCR confirmed COVID-19 children from end of June to mid September, 2020. A chi-square test (or Fischer's exact test for those variables which do not meet the chi-square assumptions) were used to determine the presence of a significant difference between the underlying characteristics of the children and COVID-19 disease severity.
    keywords: children; covid-19; disease; license; patients; preprint; study
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        item: #5783 of 7819
          id: cord-329534-deoyowto
      author: McBryde, Emma S.
       title: Role of modelling in COVID-19 policy development
        date: 2020-06-18
       words: 3145
      flesch: 33
     summary: Economic evaluation and policies have combined epidemic models and traditional economic models to address the economic consequences of COVID-19, which have informed policy calls for easing restrictions. Economic evaluation and policies have combined epidemic models and traditional economic models to address the economic consequences of COVID-19, which have informed policy calls for easing restrictions.
    keywords: countries; covid-19; epidemic; impact; modelling; models; pandemic; policy
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        item: #5784 of 7819
          id: cord-329536-3xsncmyi
      author: Passos, Lígia
       title: Impact on Mental Health Due to COVID-19 Pandemic: Cross-Sectional Study in Portugal and Brazil
        date: 2020-09-17
       words: 4367
      flesch: 48
     summary: Positivo de Coronavírus em Portugal Morte por Coronavírus no Brasil Aconteceu em 12 de Março, diz Ministério da Saúde Registada Primeira Morte por Novo Coronavírus em Portugal Rapid assessment of the impact of lockdown on the COVID-19 epidemic in Portugal António Costa Anuncia fim do Estado de Emergência e Declara Estado de Calamidade Major Brazilian Cities set Lockdowns as Virus Spreads Forced social isolation and mental health: A study on 1006 Italians under COVID-19 lockdown Mental healthcare for psychiatric inpatients during the COVID-19 epidemic Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed The outbreak of COVID-19 coronavirus and its impact on global mental health The forgotten plague: The lack of a diverse sample limits the ability to explore how some demographic characteristics (e.g., socioeconomic status) may affect mental health during the pandemic.
    keywords: anxiety; brazil; covid-19; depression; health; levels; mental; pandemic; portugal
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        item: #5785 of 7819
          id: cord-329542-srls2syv
      author: Ma, Alice
       title: Stroke and Thromboprophylaxis in the era of COVID-19
        date: 2020-10-09
       words: 2449
      flesch: 33
     summary: As stroke patients are often unable to give an adequate history of preceding COVID-19 symptoms, all stroke patients in areas with high prevalence of community transmission should be considered potential cases. Despite these studies the overall benefit of pharmacological thromboprophylaxis in stroke patients is inconclusive as a mortality or functional status improvement is not seen on follow up [9] .
    keywords: covid-19; dvt; patients; risk; stroke; thromboprophylaxis
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        item: #5786 of 7819
          id: cord-329543-gbfkce7n
      author: Tetteh, Hassan A
       title: A Leader’s Guide to Crisis Communication: Lessons from Ebola for COVID-19
        date: 2020-06-30
       words: 2885
      flesch: 49
     summary: Three fundamental goals during crisis communication include: • To increase knowledge and understanding • To enhance trust and credibility • To minimize the negative impacts of fear and concern During the initial Ebola outbreak in West Africa, officials attempted to increase knowledge and understanding of the epidemic, build trust within the affected communities, and minimize the negative impacts of fear and concern, particularly as so many lives were being lost. In crisis communication, these 3 questions guide what to communicate to individuals that are impacted by the crisis.
    keywords: communication; covid-19; crisis; ebola; outbreak; response
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        item: #5787 of 7819
          id: cord-329561-4cz2jtt7
      author: Ismael, F.
       title: Post-infection depression, anxiety and PTSD: a retrospective cohort study with mild COVID-19 patients
        date: 2020-08-31
       words: 5397
      flesch: 62
     summary: There is a need for prospective studies assessing mental health symptoms in COVID-19 patients in the post-infection period. There is a need for prospective studies assessing mental health symptoms in COVID-19 patients, evaluating the post-infection period in other regions of the world.
    keywords: anxiety; covid-19; symptoms
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        item: #5788 of 7819
          id: cord-329580-eef8mem7
      author: Rutter, Matthew D
       title: Impact of the COVID-19 pandemic on UK endoscopic activity and cancer detection: a National Endoscopy Database Analysis
        date: 2020-07-19
       words: 3729
      flesch: 41
     summary: Using the UK’s National Endoscopy Database (NED), we performed the first national analysis of the impact of the pandemic on endoscopy services and endoscopic cancer diagnosis. We have used a national database, populated by automated realtime capture of endoscopy reports and holding over 2.5 million endoscopic records, to achieve an accurate perspective of the impact of the COVID-19 pandemic on endoscopic workload and endoscopic cancer diagnosis.
    keywords: cancer; covid; covid-19; endoscopy; period; pre; procedures
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        item: #5789 of 7819
          id: cord-329626-lsbny5to
      author: Losada-Baltar, Andrés
       title: “We’re staying at home”. Association of self-perceptions of aging, personal and family resources and loneliness with psychological distress during the lock-down period of COVID-19
        date: 2020-04-13
       words: 3345
      flesch: 45
     summary: Association of self-perceptions of aging, personal and family resources and loneliness with psychological distress during the lock-down period of COVID-19 date: 2020-04-13 journal: J Gerontol B Psychol Sci Soc Sci DOI: 10.1093/geronb/gbaa048 sha: doc_id: 329626 cord_uid: lsbny5to OBJECTIVES: In addition to specific questions about risk for COVID-19, self-perceptions of aging, family and personal resources, loneliness and psychological distress were measured.
    keywords: aging; distress; loneliness; self
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        item: #5790 of 7819
          id: cord-329628-2bqrutrt
      author: Zhao, Xiaofang
       title: Early decrease in blood platelet count is associated with poor prognosis in COVID-19 patients—indications for predictive, preventive, and personalized medical approach
        date: 2020-05-14
       words: 3436
      flesch: 49
     summary: Patients still hospitalized before February 29, 2020, died on admission, with malignant tumors, previous gastrointestinal surgery, missing baseline platelet count, or platelet count detected only once, were excluded. key: cord-329628-2bqrutrt authors: Zhao, Xiaofang; Wang, Kun; Zuo, Peiyuan; Liu, Yuwei; Zhang, Meng; Xie, Songpu; Zhang, Hao; Chen, Xinglin; Liu, Chengyun title: Early decrease in blood platelet count is associated with poor prognosis in COVID-19 patients—indications for predictive, preventive, and personalized medical approach date: 2020-05-14 journal: EPMA J DOI: 10.1007/s13167-020-00208-z sha: doc_id: 329628 cord_uid: 2bqrutrt BACKGROUND: Changes in platelet count are common in COVID-19 patients.
    keywords: count; covid-19; group; non; patients; platelet; platelet count; survivors
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        item: #5791 of 7819
          id: cord-329671-f6x3if3q
      author: Hai, Shaikh
       title: Challenges and Ethical Considerations for Trainees and Attending Physicians During the COVID-19 Pandemic
        date: 2020-05-30
       words: 690
      flesch: 35
     summary: 3, 4 Second, we do not agree that medical trainees, such as residents or medical students, be fully involved in the care of COVID-19 patients. Junior residents and medical students may not have the skill set and knowledge to fully protect themselves from this pandemic.
    keywords: covid-19; pandemic
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        item: #5792 of 7819
          id: cord-329713-dqmvpqtd
      author: Pasin, Laura
       title: Regional COVID-19 Network for Coordination of SARS-CoV-2 outbreak in Veneto, Italy
        date: 2020-05-15
       words: 1820
      flesch: 37
     summary: (B) Number of coronavirus-2019 patients in Patients discharged from the intensive care unit alive (dashed green line) are distinct from patients who died in the intensive care unit Dark red bars, intensive care unit beds occupied by non-coronavirus-2019 patients None. In the following weeks, however, the number of patients requiring ICU admission exceeded the number of deaths or discharged patients (Fig 3) .
    keywords: care; covid-19; icu; number; patients
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        item: #5793 of 7819
          id: cord-329727-h47q76y8
      author: Sisó-Almirall, Antoni
       title: Prognostic factors in Spanish COVID-19 patients: A case series from Barcelona
        date: 2020-08-21
       words: 3445
      flesch: 48
     summary: This study summarizes the clinical, biological and radiological characteristics, evolution and prognostic factors of patients with COVID-19 disease in primary and community healthcare. A Cohort of Patients with COVID-19 in a Major Teaching Hospital in Europe Clinical presentation and outcome across age categories among patients with COVID-19 admitted to a Spanish Emergency Department Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area Clinical Characteristics of Covid-19 in New York City Utility of hyposmia and hypogeusia for the diagnosis of COVID-19 COVID-19)-United States The Italian coronavirus disease 2019 outbreak: recommendations from clinical practice Impact of low dose tocilizumab on mortality rate in patients with COVID-19 related pneumonia
    keywords: 95%ci; admission; covid-19; death; icu; patients
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        item: #5794 of 7819
          id: cord-329737-l8u4s73w
      author: Liew, Yixin
       title: Antimicrobial stewardship program, a vital resource for hospitals during the global outbreak of Coronavirus Disease 2019 (COVID-19)
        date: 2020-08-27
       words: 1114
      flesch: 37
     summary: Locally, our country has placed a high emphasis on identifying and isolating COVID-19 patients in our bid to contain the spread of the virus. What is also important in outbreak situations like these is on-going engagement and education of prescribers to mitigate antibiotic misuse that tends to occur with viral epidemics / pandemics, undoing years of progress in antibiotic stewardship.
    keywords: asp; covid-19; hospital; singapore
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        item: #5795 of 7819
          id: cord-329766-9bwdb6o2
      author: Liu, Xiaofan
       title: Temporal radiographic changes in COVID-19 patients: relationship to disease severity and viral clearance
        date: 2020-06-24
       words: 3194
      flesch: 44
     summary: The median viral clearance day for pneumonia patients was 21, ranging from 6 to 43; while in severe pneumonia patients, it was 20, ranging from 7.5 to 40.5 (Fig. 4B, p > 0.05) . The median values of days when the peak HRCT scores were reached in pneumonia or severe pneumonia patients were 12 vs. 14, respectively (p = 0.048).
    keywords: clearance; covid-19; disease; hrct; patients; pneumonia
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        item: #5796 of 7819
          id: cord-329770-tz8dwgzm
      author: Hamer, Mark
       title: Lifestyle Risk Factors, Inflammatory Mechanisms, and COVID-19 Hospitalization: A Community-Based Cohort Study of 387,109 Adults in UK
        date: 2020-05-23
       words: 2415
      flesch: 41
     summary: Brain Behav Immun DOI: 10.1016/j.bbi.2020.05.059 sha: doc_id: 329770 cord_uid: tz8dwgzm We conducted the first large-scale general population study on lifestyle risk factors (smoking, physical inactivity, obesity, and excessive alcohol intake) for COVID-19 using prospective cohort data with national registry linkage to hospitalisation. For non-communicable disease outcomes, lifestyle risk factors have been consistently associated with morbidity, mortality and loss of disease-free years of life.
    keywords: activity; covid-19; data; infection; lifestyle; risk; study
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        item: #5797 of 7819
          id: cord-329779-5sauq4gp
      author: Sanchis-Gomar, Fabian
       title: In Reply – Association of Renin Angiotensin System Blockers with Outcomes in Patients With COVID-19
        date: 2020-09-14
       words: 733
      flesch: 31
     summary: Despite a case series from China which reported extremely high AngII in patients with COVID-19, 8 in our cohort of 30 COVID-19 patients, circulating AngII were normal regardless of COVID-19 severity, with no significant differences between COVID-19 patients and healthy controls. Only retrospective observational studies regarding the potentially deleterious effects of ACEIs/ARBs in COVID-19 patients have been conducted to-date, and these findings need to be confirmed in prospective randomized controlled trials (RCT).
    keywords: angiotensin; covid-19
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        item: #5798 of 7819
          id: cord-329796-h7ins2a8
      author: Coombe, J.
       title: The impact of COVID-19 on the reproductive health of people living in Australia: findings from an online survey
        date: 2020-08-11
       words: 3932
      flesch: 46
     summary: Univariate analysis found that women aged 25-34 years (OR=1.6; 95%CI: 1.0, 2.5 compared with women aged 18-24 years were more likely to have accessed healthcare for their SRH reasons, and single women (OR=0.6; 95%CI: 0.3, 1.0) were less likely to have accessed services compared to women in a cohabitating relationship. Free-text responses to a question regarding the impact of COVID-19 on pregnancy plans were also collected.
    keywords: covid-19; health; participants; pregnancy; preprint; products; women
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        item: #5799 of 7819
          id: cord-329821-psv2kvfa
      author: Rascado Sedes, P.
       title: Plan de contingencia para los servicios de medicina intensiva frente a la pandemia COVID-19()
        date: 2020-04-23
       words: 3490
      flesch: 46
     summary: Asignación racional, ética y organizada de unos recursos de atención médica limitados, de manera de hacer el mayor bien al mayor número de personas. Recomendamos que, si se prevé la saturación del 100% de los servicios de medicina intensiva, debe considerarse la centralización de los recursos.
    keywords: cada; care; con; coronavirus; covid-19; critical; debe; del; hospital; influenza; intensiva; las; los; medicina; pacientes; pandemia; para; personal; plan; por; que; uci; una
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        item: #5800 of 7819
          id: cord-329852-5lr7yirs
      author: Monaco, Andrea
       title: Awareness and Impact of Non Pharmaceutical Interventions during COVID-19 Pandemic in Renal Transplant Recipients.
        date: 2020-07-21
       words: 2997
      flesch: 43
     summary: The absence of COVID-19 cases in our series was unexpected. The official data of the Ministry of Health in the KSA 7 and Italy 8 were extracted from the open access database in order to calculate Regional incidence of COVID-19 cases.
    keywords: awareness; covid-19; kt recipients; npi; recipients; survey
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        item: #5801 of 7819
          id: cord-329853-kf3kh26y
      author: Trimarchi, Hernán
       title: Eculizumab, SARS-CoV-2 and atypical hemolytic uremic syndrome
        date: 2020-09-27
       words: 1103
      flesch: 34
     summary: Although eculizumab was unable to prevent the development of severe endothelial cell injury, as assessed by increasing D-dimer levels from 292 to 10 586 ng/mL, the patient eventually recovered following dexamethasone and convalescent plasma administration. However, eculizumab administration, both chronic and early (within 3 days of diagnosis and admission) in the course of COVID-19, was unable to prevent the development of severe pneumonia and severe endothelial cell injury as assessed by a 36-fold increase in D-dimer.
    keywords: ahus; complement; covid-19; eculizumab
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        item: #5802 of 7819
          id: cord-329855-pr7g6ivu
      author: Kalfaoglu, Bahire
       title: T-cell hyperactivation and paralysis in severe COVID-19 infection revealed by single-cell analysis
        date: 2020-05-30
       words: 5370
      flesch: 41
     summary: medRxiv Structure and function of the interleukin 2 receptor: affinity conversion model Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19 Elucidating T Cell Activation-Dependent Mechanisms for Bifurcation of Regulatory and Effector T Cell Differentiation by Multidimensional and Single-Cell Analysis Role of Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand in Immune Response to Influenza Virus Infection in Mice TNF Superfamily Networks: bidirectional and interference pathways of the herpesvirus entry mediator (TNFSF14) The Measles Virus Receptor SLAMF1 Can Mediate Particle Endocytosis CD161intCD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut A timer for analyzing temporally dynamic changes in transcription during differentiation in vivo Controversies concerning thymus-derived regulatory T cells: fundamental issues and a new perspective Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor The PD-1/PD-L1 Axis and Virus Infections: A Delicate Balance Interleukin-10 production by effector T cells: Th1 cells show self control The Biology of T Regulatory Type 1 Cells and Their Therapeutic Application in Immune-Mediated Diseases IL-10 Receptor Signaling Is Essential for T<sub>R</sub>1 Cell Function In Vivo IL-10: The Master Regulator of Immunity to Infection Control of regulatory T-cell differentiation and function by T-cell receptor signalling and Foxp3 transcription factor complexes Immunological Genome Project, C. The Immunological Genome Project: networks of gene expression in immune cells Promoter H3K4 methylation dynamically reinforces activation-induced pathways in human CD4 T cells Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1 A temporally dynamic Foxp3 autoregulatory transcriptional circuit controls the effector Treg programme Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Letter to the Editor: Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease Statins induce the accumulation of regulatory T cells in atherosclerotic plaque Regulatory T cells and IL-10 levels are reduced in patients with vulnerable coronary plaques Drug Insight: the role of leptin in human physiology and pathophysiology-emerging clinical applications A Key Role of Leptin in the Control of Regulatory T Cell Proliferation Are Regulatory T Cells Defective in Type 1 Diabetes and Can We Fix Them? Metabolic Pathways in Immune Cell Activation and Quiescence Sugars and fat -A healthy way to generate functional regulatory T cells Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1 Restriction of PD-1 function by <em>cis</em>-PD-L1/CD80 interactions is required for optimal T cell responses Local Blockade of Epithelial PDL-1 in the Airways Enhances T Cell Function and Viral Clearance during Influenza Virus Infection Expression of Programmed Death-1 Ligand (PD-L) 1, PD-L2, B7-H3, and Inducible Costimulator Ligand on Human Respiratory Tract Epithelial Cells and Regulation by Respiratory Syncytial Virus and Type 1 and 2 Cytokines SnapShot: effector and memory T cell differentiation Tissue-Derived Hedgehog Proteins Modulate Th Differentiation and Disease Foxp3-Deficient Regulatory T Cells Do Not Revert into Conventional Effector CD4<sup>+</sup> T Cells but Constitute a Unique Cell Subset Comprehensive Integration of Single-Cell Data clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters MO is supported by MRC project grant (MR/S000208/1) and is currently a Visiting Associate Next, we asked if human naïve and memory CD4 + T cells can express FURIN upon receiving TCR signals.
    keywords: cd25; cd4; cells; covid-19; expression; fig; foxp3; furin; patients
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        item: #5803 of 7819
          id: cord-329863-r2vqsg5r
      author: Salamanna, Francesca
       title: Overt and non-overt disseminated intravascular coagulation and the potential role of heparin in the COVID-19 pandemic outbreak
        date: 2020-10-16
       words: 2772
      flesch: 33
     summary: Clinical characteristics of coronavirus disease 2019 in China Clinical course and risk factors for mortality of adult in patients with COVID-19 in Wuhan, China: a retrospective cohort study Non-overt coagulopathy in non-ICU patients with mild to moderate COVID-19 pneumonia Evaluation of the diagnostic performance of fibrin monomer in comparison to d-dimer in patients with overt and nonovert disseminated intravascular coagulation Chapter 146 -Excessive Bleeding and Bruising Cutaneous manifestations in COVID-19: a first perspective COVID-19 can present with a rash and be mistaken for Dengue Hypothesis for potential pathogenesis of SARS-CoV-2 infection -a review of immune changes in patients with viral pneumonia Clinical observation and management of COVID-19 patients Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Heparin therapy improving hypoxia in COVID-19 patients -a case series The potential of low molecular weight heparin to mitigate cytokine storm in severe COVID-19 patients: a retrospective clinical study. [15] [16] Several data showed that patients with severe COVID-19 who did not survive may meet the criteria for overt DIC, evidencing that this form of DIC is a strong predictor of mortality in patients developing pneumonia.
    keywords: coagulation; coronavirus; covid-19; dic; heparin; overt; patients
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        item: #5804 of 7819
          id: cord-329898-g6og7oid
      author: Song, Rok
       title: COVID-19 in Nursing Facilities: Experience in Republic of Korea
        date: 2020-08-17
       words: 1725
      flesch: 53
     summary: This sudden, and massive increase in confirmed COVID-19 cases led to several outbreaks in nursing facilities in the province. COVID-19 infected cases in the facilities were investigated to identify the infection routes, and the fatality rate of the 5 facilities.
    keywords: covid-19; facilities; infection; residents
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        item: #5805 of 7819
          id: cord-329900-lq91rb8c
      author: Seiffert, Moritz
       title: Temporal trends in the presentation of cardiovascular and cerebrovascular emergencies during the COVID-19 pandemic in Germany: an analysis of health insurance claims
        date: 2020-08-04
       words: 3354
      flesch: 35
     summary: Population trends in rates of percutaneous coronary revascularization for acute coronary syndromes associated with the COVID-19 outbreak Reduced rate of hospital admissions for ACS during Covid-19 outbreak in Northern Italy Decline of acute coronary syndrome admissions in Austria since the outbreak of COVID-19: the pandemic response causes cardiac collateral damage Societa Italiana di C, the CCUAig (2020) Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era Reduction in cardiovascular emergency admissions in Monaco during the COVID-19 pandemic Capacity changes in German certified chest pain units during COVID-19 outbreak response Disturbing effect of lockdown for COVID-19 on the incidence of infective endocarditis: a word of caution Declines in hospitalizations for acute cardiovascular conditions during the COVID-19 pandemic: a multicenter tertiary care experience 31 days of COVID-19-cardiac events during restriction of public life-a comparative study Editor's choice-comorbidity patterns among patients with peripheral arterial occlusive disease in Germany: a trend analysis of health insurance claims data Editor's choice -long term survival after femoropopliteal artery revascularisation with paclitaxel coated devices: a propensity score matched cohort analysis The impact of the lookback period and definition of confirmatory events on the identification of incident cancer cases in administrative data Mortality in the German Pharmacoepidemiological Research Database (GePaRD) compared to national data in Germany: results from a validation study The mystery of missing visits in an emergency cardiology department a time-series analysis in a tertiary Greek General Hospital Where have the STEMIs gone during COVID-19 lockdown? This analysis of a large dataset of routinely collected health insurance claims demonstrated a marked decrease in hospital admission rates for several cardiovascular and cerebrovascular emergencies during the COVID-19 pandemic in Germany.
    keywords: admission; cardiovascular; covid; covid-19; data; germany; pandemic; patients; rates
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        item: #5806 of 7819
          id: cord-329912-4tbwk8cp
      author: Loveday, Chey
       title: Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK modelling study
        date: 2020-08-24
       words: 5353
      flesch: 38
     summary: Based on linear regression from observational data of diagnosisto-treatment interval, our analyses suggest CRC pathway delays are associated with substantial impact on survival and LYs lost. As per the sensitivity analysis and detailed in our previous health-systems analyses of cancer pathway delays, the outputs of our model are predicated heavily on accuracy of the delay-HR.
    keywords: cancer; covid-19; crc; data; delay; fit; impact; infection; patients; referral; survival
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        item: #5807 of 7819
          id: cord-329925-p4hfqath
      author: JunziShi
       title: Radiology workload changes during the COVID-19 pandemic: implications for staff redeployment
        date: 2020-10-02
       words: 3139
      flesch: 34
     summary: Public Health Nurs NIH Public Access Managing high clinical suspicion COVID-19 inpatients with negative RT-PCR: A pragmatic and limited role for thoracic CT Data shows decrease in hospital outpatient volume since COVID-19 Practical Considerations for Treating Patients With Cancer in the COVID-19 Pandemic Responding to Covid-19: The primary outcome measure was the change in radiology report volume, measured as the preversus post-intervention difference in number of radiology reports from CT, MR, US, radiographs, IR, and nuclear medicine examinations.
    keywords: care; covid-19; divisions; hospital; imaging; outpatient; radiology; staff; volume
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        item: #5808 of 7819
          id: cord-329939-spa16qhz
      author: Miranda, Eduardo P.
       title: Challenges in the Practice of Sexual Medicine in the Time of COVID-19
        date: 2020-05-23
       words: 1257
      flesch: 44
     summary: On 97 the other hand, public services have been mostly devoted to the fight against 98 COVID-19, and many sexual medicine experts who are public employees have 99 been allocated to work in the frontline or in regulation services. As interviews are the 165 main core of sexual medicine practice, telemedicine might be more easily applied 166 within our specialty.
    keywords: covid-19; medicine; patients; practice
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        item: #5809 of 7819
          id: cord-329947-so64wlo2
      author: Poggiali, Erika
       title: COVID-19, Chronic Obstructive Pulmonary Disease and Pneumothorax: A Frightening Triad
        date: 2020-06-01
       words: 1094
      flesch: 42
     summary: Risks factors for pneumothorax include smoking, genetics, lung disease, mechanical ventilation and previous pneumothorax. High-resolution chest CT scan (HRCT) confirmed the diagnosis of left pneumothorax and revealed diffuse emphysema, as observed in chronic obstructive pulmonary disease (COPD), and small consolidations in both lower lobes, suggestive of COVID-19 pneumonia (Fig. 1) .
    keywords: covid-19; disease; pneumothorax
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        item: #5810 of 7819
          id: cord-329953-8nq7fvfh
      author: Le Grange, Lesley
       title: Covid-19 pandemic and the prospects of education in South Africa
        date: 2020-10-19
       words: 6256
      flesch: 45
     summary: Access to any form of online learning for the majority of school learners remains a pipedream; thus, the Covid-19 pandemic has likewise laid bare the severity of the digital divide in South Africa (Davids 2020) . Such schools lack basic sanitation and water infrastructure; moreover, their inferior facilities will make physical distancing a challenge.
    keywords: africa; biology; covid-19; currere; curriculum; education; human; learners; pandemic; school; south; ubuntu
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        item: #5811 of 7819
          id: cord-329985-5rji08p7
      author: Robba, Chiara
       title: Distinct phenotypes require distinct respiratory management strategies in severe COVID-19
        date: 2020-05-11
       words: 4384
      flesch: 35
     summary: The experience in COVID-19 patients from Wuhan was similar, with a high rate of noninvasive support failure and need for intubation and mechanical ventilation in 76% of cases; nevertheless, there was no difference in mortality between patients receiving noninvasive vs invasive ventilation . Continuous infusion of neuromuscular blocking agents (NMBA) should be reserved for COVID-19 patients in which intermittent dosing may not suffice, such as: patients undergoing prone positioning, persistent ventilator asynchrony, and those with high plateau pressures (Alhazzani et al., 2013) .
    keywords: chest; covid-19; failure; patients; ventilation
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        item: #5812 of 7819
          id: cord-329989-176cvimy
      author: Federico, Antonio
       title: Scientific publishing in the COVID-19 era: successes and pitfalls
        date: 2020-07-02
       words: 1746
      flesch: 36
     summary: These data, though limited, indicate that brainstem involvement may play a role in respiratory failure and perhaps in the high death rate of COVID-19 patients. Moreover, the weaning failure from mechanical ventilation due to central respiratory drive depression may underlie the unusually long stay in the ICU reported for COVID-19 patients.
    keywords: authors; covid-19; data; pandemic; patients
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        item: #5813 of 7819
          id: cord-329996-f2hxpat3
      author: Wahlster, Sarah
       title: The COVID-19 Pandemic’s Impact on Critical Care Resources and Providers: A Global Survey
        date: 2020-09-11
       words: 3839
      flesch: 46
     summary: The high prevalence of provider burnout, and its association with reported insufficient resources and poor communication from supervisors suggest a need for targeted interventions to support HCPs on the front lines. Limiting MV for COVID-19 patients was reported by 16% of respondents, was lowest in North America (10%), and was associated with reduced ventilator availability (aRR:2.10, 95% CI:1.61-2.74).
    keywords: burnout; care; covid-19; hcps; icu; patients; respondents
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        item: #5814 of 7819
          id: cord-330017-t14o7rua
      author: Galiero, Raffaele
       title: The Importance of Telemedicine during COVID-19 Pandemic: A Focus on Diabetic Retinopathy
        date: 2020-10-14
       words: 3670
      flesch: 31
     summary: The latter is mainly due to the disparity between the low number of ophthalmologists and the large population of diabetic patients, as well as to the uncomfortable traditional fundus oculi, which provide pupil dilation after instillation of eye drops. Once daily self-monitoring of blood glucose (SMBG) improves glycemic control in oral hypoglycemic agents (OHA)-treated diabetes: SMBG-OHA follow-up study A structured self-monitoring of blood glucose approach in type 2 diabetes encourages more frequent, intensive, and effective physician interventions: results from the STeP study WellDoc mobile diabetes management randomized controlled trial: change in clinical and behavioral outcomes and patient and physician satisfaction Cluster-randomized trial of a mobile phone personalized behavioral intervention for blood glucose control Use of a novel, remotely connected diabetes management system is associated with increased treatment satisfaction, reduced diabetes distress, and improved glycemic control in individuals with insulin-treated diabetes: first results from the personal diabetes management study Improving self-monitoring of blood glucose among adults with type 1 diabetes: results of the Mobile™ study Sensitivity and specificity of automated analysis of single-field non-mydriatic fundus photographs by Bosch DR Algorithm-comparison with mydriatic fundus photography (ETDRS) for screening in undiagnosed diabetic retinopathy Use of telemedicine technologies in diabetes prevention and control in resource-constrained settings: lessons learned from emerging economies Validation of smartphone based retinal photography for diabetic retinopathy screening Long-term comparative effectiveness of telemedicine in providing diabetic retinopathy screening examinations: a randomized clinical trial Effectiveness and safety of screening for diabetic retinopathy with two nonmydriatic digital images compared with the seven standard stereoscopic photographic fields A telemedical approach to the screening of diabetic retinopathy: digital fundus photography Implementation and evaluation of a largescale teleretinal diabetic retinopathy screening program in the Los Angeles County Department of Health Services Telemedicine for screening diabetic retinopathy: the NO BLIND Italian multicenter study Smartphone assisted slit lamp free anterior segment imaging: a novel technique in teleophthalmology A systematic review of healthcare applications for smartphones Comparison of smartphone ophthalmoscopy with slit-lamp biomicroscopy for grading diabetic retinopathy Telemedicine and diabetic retinopathy: moving beyond retinal screening Diabetic retinopathy screening using tele-ophthalmology in a primary care setting Smartphones, tele-ophthalmology, and VISION 7 Journal of Diabetes Research Teleophthalmology and vision 2020 in South Africa Improving access to eye care: teleophthalmology in Alberta, Canada A comparative cost analysis of digital fundus imaging and direct fundus examination for assessment of diabetic retinopathy Management of cardiovascular risk factors in advanced type 2 diabetic nephropathy: a comparative analysis in nephrology, diabetology and primary care settings
    keywords: covid-19; diabetes; management; monitoring; pandemic; patients; retinopathy; screening; telemedicine
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        item: #5815 of 7819
          id: cord-330022-n3d130t8
      author: Pan, Daniel
       title: The impact of ethnicity on clinical outcomes in COVID-19: A systematic review
        date: 2020-06-03
       words: 5071
      flesch: 39
     summary: We inspected the full text, baseline characteristics tables and any relevant supplementary materials to explore whether ethnicity was reported and whether its relation with clinical outcomes of COVID-19 patients was examined (Fig. 1 ). We found published evidence to suggest that those of Black ethnicity may be at higher risk of acquiring SARS-CoV-2 infection, compared to White patients.
    keywords: articles; covid-19; data; ethnicity; literature; mortality; outcomes; patients; risk; sars
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        item: #5816 of 7819
          id: cord-330050-05nnihst
      author: Li, Yang
       title: Emergency trauma care during the outbreak of corona virus disease 2019 (COVID-19) in China
        date: 2020-05-15
       words: 4386
      flesch: 42
     summary: To regulate the emergency treatment of trauma patients during the outbreak, we drafted this paper from a trauma surgeon perspective according to practical experience in Wuhan. The article illustrates the general principles for the triage and evaluation of trauma patients during the outbreak of COVID-19, indications for emergency surgery, and infection prevention and control for medical personnel, providing a practical algorithm for trauma care providers during the outbreak period.
    keywords: care; china; coronavirus; covid-19; infection; novel; operation; outbreak; patients; personnel; trauma
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        item: #5817 of 7819
          id: cord-330061-q4xi260z
      author: Ferreira, João Guimarães
       title: Pneumothorax as a late complication of COVID-19
        date: 2020-08-31
       words: 2424
      flesch: 41
     summary: Coronavirus disease (COVID-19): situation report -200 Deep impact of COVID-19 in the healthcare of Latin America: the case of Brazil Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Severe Covid-19 Frequency and distribution of chest radiographic findings in COVID-19 positive patients Sensitivity of chest CT for COVID-19: comparison to RT-PCR Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection Laboratory abnormalities in patients with COVID-2019 infection Dexamethasone in hospitalized patients with Covid-19: preliminary report Therapeutic strategies for critically ill patients with COVID-19 SARS-CoV-2 infection associated with spontaneous pneumothorax Diseases of the diaphragm, chest wall, pleura and mediastinum Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Analysis of 92 deceased patients with Covid-19 Coronavirus disease 2019 (COVID-19): a systematic review of imaging findings in 919 patients Spontaneous pneumothorax and subcutaneous emphysema in COVID-19 patient: case report Pathological findings of COVID-19 associated with acute respiratory distress syndrome Whereas some patients with COVID-19 developed pneumothorax in association with risk factors, such as mechanical ventilation, in others the only factor was the viral pneumonia itself 19 .
    keywords: cases; chest; covid-19; day; disease; patients; pneumothorax
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        item: #5818 of 7819
          id: cord-330063-rigpx36k
      author: Williams, Owain Hedd
       title: Multiple internal border zone infarcts in a patient with COVID-19 and CADASIL
        date: 2020-06-09
       words: 1203
      flesch: 22
     summary: We recommend that further research be conducted into the pathophysiology of COVID-19 related stroke and therapies that target stabilising the vascular endothelium. There is evidence of chronic cerebral hypoperfusion in CADASIL, with a proposed mechanism being impairment in the myogenic component of autoregulation where vascular smooth muscle constricts or dilates to transmural pressure changes.(1) Internal border zone infarcts have been reported in nine patients with CADASIL; whereby six had documented systemic hypotension, one occurring with intercurrent Influenza A infection.
    keywords: cadasil; covid-19; endothelial; infarcts
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        item: #5819 of 7819
          id: cord-330074-5iqqgy65
      author: Patel, Smit D.
       title: Malignant Cerebral Ischemia in A COVID-19 Infected Patient: Case Review and Histopathological Findings
        date: 2020-08-05
       words: 1453
      flesch: 25
     summary: The Lancet Psychiatry SARS-CoV-2 and Stroke in a New York Healthcare System Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Coexistence of COVID-19 and acute ischemic stroke report of four cases Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Ischemic Stroke Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Arterial thromboembolic complications in COVID-19 in lowrisk patients despite prophylaxis Thrombosis risk associated with COVID-19 infection. Eventually, the P a g e | 6 Ischemic stroke and COVID-19 infection patient had worsening respiratory status and multifactorial shock.
    keywords: covid-19; infection; ischemic; stroke
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        item: #5820 of 7819
          id: cord-330089-926y1hfj
      author: Russo, Vincenzo
       title: Effect of Triple Combination Therapy With Lopinavir-Ritonavir, Azithromycin, and Hydroxychloroquine on QT Interval and Arrhythmic Risk in Hospitalized COVID-19 Patients
        date: 2020-10-08
       words: 2647
      flesch: 31
     summary: This study aims to describe the incidence of extreme QTc interval prolongation among COVID-19 patients on this experimental treatment and to identify the clinical features associated with extreme QTc prolongation. Twenty patients (23%) showed extreme QTc interval prolongation; no clinical, electrocardiographic or pharmacological characteristics have been associated to extreme QTc prolongation, except the history of ischemic stroke (P= 0,007).
    keywords: extreme; interval; patients; prolongation; qtc
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        item: #5821 of 7819
          id: cord-330093-asba80bi
      author: Leung, Janice M.
       title: Smoking, ACE-2 and COVID-19: ongoing controversies
        date: 2020-07-16
       words: 2785
      flesch: 40
     summary: K. Farsalinos and co-workers, through analysis of the pooled prevalence of current smoking across 11 case series determined that current smoking status was significantly lower than expected gender-and age-adjusted prevalence in COVID-19 patients. [2] , of 220 hospitalised and 311 nonhospitalised patients with COVID-19 patients across six acute care hospitals and associated outpatient clinics in metropolitan Atlanta, Georgia, for instance, demonstrated that smoking was an independent risk factor for COVID-19 hospitalisation, carrying an odds ratio of 2.3 (95% CI 1.2-4.5).
    keywords: cigarette; coronavirus; covid-19; disease; nicotine; patients; smoking
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        item: #5822 of 7819
          id: cord-330104-wgo4pml6
      author: Farrugia, Gianrico
       title: Innovation Lessons From the COVID-19 Pandemic
        date: 2020-06-06
       words: 1672
      flesch: 42
     summary: In the ensuing weeks, health care organizations, industry partners, and government agencies worldwide have quickly come together to address pandemic challenges such as scaling high-quality laboratory tests, conducting treatment research, and enabling virtual health care in a time of social distancing. 2 To stem pandemic-related deaths and prevent health care systems from being overwhelmed with sick patients, governments responded by limiting travel, closing schools, issuing stay-at-home orders, making emergency investments in health care, scaling testing, and using data and technology to trace contacts.
    keywords: care; covid-19; health; mayo; pandemic
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        item: #5823 of 7819
          id: cord-330120-xd9l948d
      author: van Dyck, Laura I.
       title: Combating Heightened Social Isolation of Nursing Home Elders: The Telephone Outreach in the COVID-19 Outbreak Program
        date: 2020-06-05
       words: 1496
      flesch: 35
     summary: To address social isolation in nursing home residents, the Yale School of Medicine Geriatrics Student Interest Group initiated a Telephone Outreach in the COVID-19 Outbreak (TOCO) Program that implements weekly phone calls with student volunteers. The TOCO program achieved initial success and promotes the social wellbeing of nursing home residents.
    keywords: nursing; program; residents
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        item: #5824 of 7819
          id: cord-330126-sny9w9y8
      author: Deng, Fuxue
       title: Corticosteroids in diabetes patients infected with COVID-19
        date: 2020-06-25
       words: 1154
      flesch: 37
     summary: In a large sample of 1099 patients with COVID-19 infection, 204 (18.6%) received intravenous corticosteroids, and the percentage of corticosteroids was higher in severe patients than in mild or moderate patients [6] . The combination of continuous renal replacement therapy and tocilizumab may benefit severe patients in clinical therapy.
    keywords: china; covid-19; diabetes; patients
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        item: #5825 of 7819
          id: cord-330129-izr62c68
      author: Omer, Sumaira
       title: Preventive measures and management of COVID-19 in pregnancy
        date: 2020-04-09
       words: 1964
      flesch: 47
     summary: What are the risks of COVID-19 infection in pregnant women? Interim infection prevention and control recommendations for patients with suspected or confirmed coronavirus disease 2019 (COVID-19) in healthcare settings Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected: interim guidance Chinese expert consensus on the perinatal and neonatal management for the prevention and control of the 2019 novel coronavirus infection National Health Commission of the People's Republic of China. For effective management, pregnant women with suspected COVID-19 should be isolated and then transferred to a hospital equipped with sufficient health facilities and fully trained clinicians to take proper care of critically ill obstetric patients.
    keywords: coronavirus; covid-19; health; infection; ncov; women
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        item: #5826 of 7819
          id: cord-330136-o8df8szx
      author: Fan, Hua
       title: Cardiac injuries in patients with coronavirus disease 2019: Not to be ignored
        date: 2020-05-11
       words: 2170
      flesch: 49
     summary: Therefore, it is of great clinical significance to explore the clinical features and factors influencing prognosis of COVID-19 patients. This study enrolled COVID-19 patients, including 47 non-survivors and 26 survivors, admitted to the ICU.
    keywords: covid-19; patients; survivors; tni
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        item: #5827 of 7819
          id: cord-330151-7ylnxtcq
      author: Fang, Shilin
       title: Decreased complement C3 levels are associated with poor prognosis in patients with COVID-19: a retrospective cohort study
        date: 2020-10-05
       words: 867
      flesch: 29
     summary: The levels of total immunoglobulins (IgG, IgM, IgA, and IgE), complement (C3, C4) results were retrospectively analyzed in COVID-19 patients. Inhibition of the complement pathway might be an effective therapeutic to COVID-19 patients. patients.
    keywords: complement; covid-19; patients
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        item: #5828 of 7819
          id: cord-330159-vm30ohrb
      author: Beretta, Federica
       title: Practical Considerations for the Management of Cushing's Disease and COVID-19: A Case Report
        date: 2020-09-11
       words: 2752
      flesch: 38
     summary: Conclusion: Adrenal insufficiency might be a clinical challenge that needs a prompt treatment also in CS patients during COVID-19 infection. Several treatment options are available for CS patients; however, some of them might be challenging especially in the context of COVID-19 infection (12) .
    keywords: covid-19; disease; infection; insufficiency; patients; treatment
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        item: #5829 of 7819
          id: cord-330171-l7p0sxqu
      author: Branicki, Layla J.
       title: COVID‐19, Ethics of Care, and Feminist Crisis Management
        date: 2020-06-17
       words: 5350
      flesch: 35
     summary: I present my comparison of the rational approach to crisis management and feminist crisis management in table one, below. Rationalist approaches to crisis management are typified by utilitarian logics, masculine and militaristic language, and the belief that crises follow linear processes of signal detection, preparation/prevention, containment, recovery, and learning.
    keywords: care; caring; covid-19; crisis; crisis management; ethics; feminist; gilligan; management; organization
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        item: #5830 of 7819
          id: cord-330198-pwkxgbxk
      author: Cai, Xiaofang
       title: Clinical manifestations and pathogen characteristics in children admitted for suspected COVID-19
        date: 2020-10-27
       words: 4293
      flesch: 45
     summary: Although we strictly adhered to two pre-examinations and triage for all outpatients, most of the probable and confirmed COVID-19 cases were admitted from the fever clinic, and 12.5% (97/773) of the probable COVID-19 cases (including 5.3% (13/245) of confirmed COVID-19 cases) with atypical symptoms or critical illness were admitted from the emergency department. The incidence of fever was higher in non-COVID-19 cases (31, 75.6%) than that in confirmed COVID-19 cases (7, 53.8%) and suspected COVID-19 cases (19, 44.2%) (P = 0.013).
    keywords: cases; cells; children; cov-2; covid-19; non; patients; sars
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        item: #5831 of 7819
          id: cord-330205-hj0o33xo
      author: Garrido, Isabel
       title: “Cirrhosis management in a major referral center during COVID-19”
        date: 2020-07-15
       words: 1133
      flesch: 45
     summary: In particular, we share with Boettler et al the concern with cirrhotic patients. In cirrhotic patients with COVID-19, endoscopy was performed only in life-3 threatening conditions.
    keywords: cirrhosis; covid-19; liver; patients
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        item: #5832 of 7819
          id: cord-330239-l8fp8cvz
      author: Oyelade, O. N.
       title: Deep Learning Model for Improving the Characterization of Coronavirus on Chest X-ray Images Using CNN
        date: 2020-11-03
       words: 6450
      flesch: 44
     summary: Prospective Predictions Are the Future ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseases Automated detection of COVID19 cases using deep neural networks with X-ray images COVID-Net: A tailored deep convolutional neural network design for detection of COVID-19 cases from chest radiography images Covid-19: automatic detection from x-ray images utilizing transfer learning with convolutional neural networks Coronet: The Lancet infectious diseases A Machine Learning Solution Framework for Combatting COVID-19 in Smart Cities from Multiple Dimensions Applications of machine learning and artificial intelligence for Covid-19 (SARS-CoV-2) pandemic: A review Deep Convolutional Neural Networks based Classification model for COVID-19 Infected Patients using Chest X-ray Images Classification of the COVID-19 infected patients using DenseNet201 based deep transfer learning Classification of COVID-19 patients from chest CT images using multi-objective differential evolution-based convolutional neural networks Coronavirus (covid-19) classification using ct images by machine learning methods Automatic Detection of COVID-19 Using X-ray Images with Deep Convolutional Neural Networks and Machine Learning Classification of COVID-19 from Chest X-ray images using Deep Convolutional Neural Networks Weakly Supervised Deep Learning for COVID-19 Infection Detection and Classification from CT Images Fast Deep Learning Computer-Aided Diagnosis against the Novel COVID-19 pandemic from Digital Chest X-ray Images The experimental results of multiclass classification for four (4) experimental scenarios show that most scenarios have more than 99% accuracy.
    keywords: chest; chest x; cnn; covid-19; images; learning; model; performance; preprint; ray
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        item: #5833 of 7819
          id: cord-330261-8sb9sc7o
      author: Sahoo, D. P.
       title: Hospital based contact tracing of COVID-19 patients and health care workers and risk stratification of exposed health care workers during the COVID-19 Pandemic in Eastern India
        date: 2020-11-04
       words: 3302
      flesch: 53
     summary: The test positivity rate of high risk contact was 3.82% and for low risk contact was 1.9%. Results: Out of 3411 contacts 890 (26.1%) were high risk contacts and 2521 (73.9%) were low risk contacts.
    keywords: contact; covid-19; hcws; preprint; risk; tracing
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        item: #5834 of 7819
          id: cord-330299-fcqtstpk
      author: Tsuchiya, Atsunori
       title: Therapeutic potential of mesenchymal stem cells and their exosomes in severe novel coronavirus disease 2019 (COVID-19) cases
        date: 2020-06-22
       words: 3063
      flesch: 40
     summary: The International Society for Cellular Therapy position statement A comparative analysis of multipotent mesenchymal stromal cells derived from different sources, with a focus on neuroregenerative potential Status of and candidates for cell therapy in liver cirrhosis: overcoming the point of no return in advanced liver cirrhosis Clinical trials using mesenchymal stem cells in liver diseases and inflammatory bowel diseases Mesenchymal stem cell therapies for liver cirrhosis: MSCs as conducting cells for improvement of liver fibrosis and regeneration Development of a non-alcoholic steatohepatitis model with rapid accumulation of fibrosis, and its treatment using mesenchymal stem cells and their small extracellular vesicles Mesenchymal stem cells and induced bone marrow-derived macrophages synergistically improve liver fibrosis in mice Mesenchymal stem cells cultured under hypoxic conditions had a greater therapeutic effect on mice with liver cirrhosis compared to those cultured under normal oxygen conditions Effects of human adipose tissuederived and umbilical cord tissue-derived mesenchymal stem cells in a dextran sulfate sodium-induced mouse model Insurance approval of mesenchymal stem cell for acute GVHD in Japan: need of follow up for some remaining concerns Early injection of human adipose tissuederived mesenchymal stem cell after inflammation ameliorates dextran sulfate sodium-induced colitis in mice through the induction of M2 macrophages and regulatory T cells Mesenchymal stromal cell-derived extracellular vesicles for regenerative therapy and immune modulation: progress and challenges toward clinical application Concise review: developing best-practice models for the therapeutic use of extracellular vesicles Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines Extracellular vesicles or exosomes? key: cord-330299-fcqtstpk authors: Tsuchiya, Atsunori; Takeuchi, Suguru; Iwasawa, Takahiro; Kumagai, Masaru; Sato, Takeki; Motegi, Satoko; Ishii, Yui; Koseki, Youhei; Tomiyoshi, Kei; Natsui, Kazuki; Takeda, Nobutaka; Yoshida, Yuki; Yamazaki, Fusako; Kojima, Yuichi; Watanabe, Yusuke; Kimura, Naruhiro; Tominaga, Kentaro; Kamimura, Hiroteru; Takamura, Masaaki; Terai, Shuji title: Therapeutic potential of mesenchymal stem cells and their exosomes in severe novel coronavirus disease 2019 (COVID-19) cases date: 2020-06-22 journal:
    keywords: cases; cells; coronavirus; covid-19; exosomes; mesenchymal; mscs; patients
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        item: #5835 of 7819
          id: cord-330320-27dj69i1
      author: Valitutti, Francesco
       title: Effect of Population Lockdown on Pediatric Emergency Room Demands in the Era of COVID-19
        date: 2020-09-18
       words: 2655
      flesch: 40
     summary: The aim of this study was to assess the impact of the COVID-19 pandemic and population lockdown on pediatric ED consultations. The COVID-19 pandemic and the following lockdown unveiled the inappropriateness of the majority of pediatric ED consultations.
    keywords: care; children; consultations; covid-19; emergency; march; pediatric
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        item: #5836 of 7819
          id: cord-330346-9zi5culm
      author: Uddin Chowdhury, Md Reaz
       title: COVID-19 presented with syndrome of inappropriate ADH SECRETION(SIADH):a case report from Bangladesh
        date: 2020-11-12
       words: 1697
      flesch: 36
     summary: Emergency blood/serum send for laboratory investigations and were found(see Table: 1) serum sodium of 114mEq/L(normal range 135-145 mEq/L),potassium was 3.6mEq/L(3.5-5.5mEq/L),Other laboratory investigation showed Hemoglobin (Hb%) was 11.1gm/dl (normal range 11.0-16.0 gm/dl),Erythrocyte sedimentation rate(ESR) (westergren) was 54mm in 1 st hour ,total white blood cell count(WBC) was 6900/cmm (normal range 4000-11000/cmm), differential count of neutrophils was 74% (normal range 40-75%), lymphocytes was 11%(normal range 20-50%), eosinophils was 0%(normal range 2-9%),platelet count was 177,000/cmm (normal range 150.000-400,000/cmm),random blood sugar was 5.5mmol/L (normal up to 7.8mmol/L),serum creatinine was 1.3mg/dl (normal range 0.5-1.2mg/dl),SGPT was 16 U/L( normal up to 32U/L),C reactive protein(CRP) was 65mg/l(normal range<7mg/l ),serum ferritin was J o u r n a l P r e -p r o o f 317ng/ml(normal 20-250ng/ml in female), troponin I was <0.1ng/ml (normal <0.1ng/ml),serum thyroid stimulating Figure :1 ). Further workup revealed low normal blood urea which was 11.6mg/dl(normal range 10-50mg/dl), low serum uric acid 2.4mg/dl(normal range 2.4-5.7mg/dl in female),urine osmolality of 353mOsm/kg(reference value 60-1400 mOsm/kg), low plasma osmolality which was 219 mOsm/kg(reference value 275-295)(275-295, urinary sodium was 34 mEq/L(around 20 mEq/L), random serum cortisol at 8 AM was 14mcg/dl(normal ranges :10-20mcg/dl),ACTH stimulation test was not done.
    keywords: covid-19; disease; hyponatremia; pneumonia; range; siadh
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        item: #5837 of 7819
          id: cord-330368-rk31cwl4
      author: Bowden, Kasey
       title: Harnessing the Power of Hospitalists in Operational Disaster Planning: COVID-19
        date: 2020-07-13
       words: 2463
      flesch: 40
     summary: The last guiding principle was conscientiousness of resources (people, systems, and cost), knowing that any plan needed sustainability, particularly since successfully flattening the curve would mean prolonging the plateau and thus prolongation of the surge of COVID-19 patients over time. To increase capacity while limiting the number of providers in the hospital, strategies were developed for remote patient care from home.
    keywords: care; covid-19; hospital; medicine; patients; providers; teams
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        item: #5838 of 7819
          id: cord-330369-75cotmn2
      author: López, Verónica
       title: Recommendations on management of the SARS-CoV-2 coronavirus pandemic (Covid-19) in kidney transplant patients
        date: 2020-04-06
       words: 3483
      flesch: 42
     summary: The Spanish Nephrology Society (www.senefro.org) and the Spanish Transplant Society (www.setrasplante.org) are conveying the recommendations of measures for prevention and contingency against COVID-19 in kidney patients, including kidney transplant patients. Most of the transplant centers in Spain already have cases of kidney transplant patients affected by COVID-19 that have not been published.
    keywords: coronavirus; covid-19; dose; infection; kidney; patients; population; transplant
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        item: #5839 of 7819
          id: cord-330388-lq6fsl9i
      author: Adam, E. J.
       title: COVID-19: could CT provide the best population level biomarker? Incidental COVID-19 in major trauma patients suggests higher than predicted rates of infection in London
        date: 2020-10-31
       words: 2560
      flesch: 47
     summary: Recognised CT features of COVID-19 were used to determine whether there were major or minor signs indicating COVID-19 lung disease on the emergency scans (10) . The average duration of COVID-19 signs on CT for the infected general population with asymptomatic or mild disease is estimated to be 2 weeks.
    keywords: covid-19; disease; population; study; trauma
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        item: #5840 of 7819
          id: cord-330395-2qoyrqmj
      author: Huq, Samin
       title: COVID-19 in Bangladesh: Data deficiency to delayed decision
        date: 2020-04-15
       words: 1463
      flesch: 53
     summary: Also, decision making based on the current prevalence of COVID-19 can undermine the Photo: The distribution of positive COVID-19 cases across the districts of Bangladesh (8 April 2020), data source: https://iedcr.gov.bd/. The lack of data has led to unplanned decision making and contributed to skewing global data. issue of the health system preparedness without a careful understanding of the dynamics of COVID-19 evidenced worldwide. Although scarcity of test kits and lack of awareness from the general public certainly contributed to the crisis, Bangladesh is one of the few countries which had more than two months to prepare for COVID-19 crisis.
    keywords: bangladesh; covid-19; health; testing
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        item: #5841 of 7819
          id: cord-330411-hg1cxcs7
      author: Keddie, S.
       title: Laboratory biomarkers associated with COVID-19 severity and management
        date: 2020-10-22
       words: 2409
      flesch: 38
     summary: Neurological cases had lower levels of COVID-19 disease severity markers, which may be accounted for in part by selection bias, where patients were hospitalised due to neurological disease with concurrent, less severe COVID-19 infection compared to those admitted primarily due to COVID-19 respiratory failure. This study comprehensively explored clinical disease features and routine laboratory tests against specialist cytokine biomarkers associated with COVID-19 disease and its complications, to address their association with disease severity, respiratory intervention and outcome.
    keywords: covid-19; crp; disease; il-6; patients; severity
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        item: #5842 of 7819
          id: cord-330431-9txstz4n
      author: Nomikos, Iakovos N
       title: What Else but Covid-19 Pandemic? Lessons Learned
        date: 2020-07-11
       words: 2564
      flesch: 40
     summary: As knowledge develops about the risks for cancer patients during the pandemic, major considerations for management include that both the cancer condition itself and its treatment may increase risk of serious COVID-19 complications. For this reason, many publications suggested recommendations for the prioritisation, treatment, and triage of cancer patients during the COVID-19 pandemic [13] .
    keywords: cancer; care; covid-19; health; pandemic; patients; treatment
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        item: #5843 of 7819
          id: cord-330461-4bncbqsb
      author: Warth, Lucian C.
       title: How Has COVID-19 Affected Our Orthopedic Implant Industry Partners? Implications for the Surgeon-Industry Relationship in 2020 and Beyond
        date: 2020-04-28
       words: 2971
      flesch: 40
     summary: In summary, the majority of AAHKS Industry Partner responses indicated a forward-thinking 203 mindset in the face of COVID-19 induced uncertainty. 34 The cessation of elective total hip and knee arthroplasty has also had a dramatic effect on 35 AAHKS Industry Partners.
    keywords: aahks; covid-19; industry; partners; support; surgeon
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        item: #5844 of 7819
          id: cord-330464-j4o7m9ck
      author: Ng, Jun Jie
       title: Experience from a Singapore tertiary hospital with restructuring a vascular surgery practice in response to national and institutional policies during the COVID-19 pandemic
        date: 2020-05-23
       words: 2597
      flesch: 50
     summary: Crucial institutional policies had to be implemented to increase 3 resources for the potential influx of COVID-19 patients. As part of our inpatient services, we provide an emergency vascular surgical consult 1 service to medical teams that are managing COVID-19 patients.
    keywords: cases; covid-19; patients; singapore; surgery; team
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        item: #5845 of 7819
          id: cord-330478-g9n2mfni
      author: Hattenbach, Lars-Olof
       title: Krisenstrategien der Kliniken während der Pandemie
        date: 2020-07-01
       words: 1551
      flesch: 28
     summary: Im Zuge der Umstellung der Kliniken auf die zu erwartende Versorgung von COVID-19-Patienten mit Bereitstellung möglichst großer Intensivbettenkapazitäten und Beatmungsplätzen ist es dabei v. a. zu erheblichen Die Erkenntnisse dieser Umfrage sollen dazu beitragen, die Bedeutung der Aufrechterhaltung der Patientenversorgung in unserem Fach hervorzuheben und auf zukünftige Herausforderungen besser vorbereitet zu sein. Interessenkonflikt.
    keywords: care; cov-2; covid-19; den; der; die; eine; mit; pandemic; patienten; sars; und; von
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        item: #5846 of 7819
          id: cord-330492-kbob8z48
      author: Vervoort, Dominique
       title: Assessing the Collateral Damage of the Novel Coronavirus: A Call to Action for the Post-COVID-19 Era
        date: 2020-04-30
       words: 1559
      flesch: 34
     summary: These include ensuring that a separate emergency team remains active and able to accept cases, minimizing crossover infections among patients and health workers, dedicating select hospitals, catheterization labs, operating rooms, and wards to non-COVID-19 patients, and allowing other healthcare personnel to become available when COVID-19 patients surge. Furthermore, it may include the need to have dedicated hospitals caring for COVID-19 patients only, whilst other hospitals outside heavily-hit areas take care of non-COVID-19 patients.
    keywords: care; covid-19; health; patients; time
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        item: #5847 of 7819
          id: cord-330545-jrmott3i
      author: Abuzeineh, Mohammad
       title: Telemedicine in the Care of Kidney Transplant Recipients with COVID-19: Case Reports
        date: 2020-07-16
       words: 3337
      flesch: 45
     summary: While there is limited information about the duration of viral shedding for immunosuppressed patients and it is not yet known whether protracted persistent NAT positivity reflects continued capacity for viral transmission, our case reports suggest longer periods of self-quarantine are appropriate for kidney transplant patients with 19 For patients with scheduled visits/tests that cannot be performed through telemedicine and that will occur within 6 weeks of symptom onset, patients may undergo COVID-19 repeat test-based strategy as outpatients (Table 3) . Our experience emphasizes the opportunities of telemedicine in the safe management of kidney transplant patients with COVID-19 from home to inpatient settings and in the maintenance of uninterrupted follow-up care for such immunosuppressed patients with prolonged viral shedding.
    keywords: care; covid-19; kidney; patients; recipients; telemedicine; transplant; visit
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        item: #5848 of 7819
          id: cord-330550-cxdrac0o
      author: Canonico, Mario Enrico
       title: The tug-of-war between coagulopathy and anticoagulant agents in patients with COVID-19
        date: 2020-05-08
       words: 921
      flesch: 32
     summary: Among anticoagulant agents, unfractionated heparin, low molecular weight heparin (LMWH), and fondaparinux could be safely coadministered with COVID-19 experimental drugs, since there are neither proven nor expected interactions. In this complex scenario, an important clinical issue seems to be represented by a suspected higher prevalence of thrombo-embolic events in COVID-19 patients.
    keywords: agents; covid-19; patients
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        item: #5849 of 7819
          id: cord-330597-nftwj0d5
      author: Hopfer, Helmut
       title: Hunting coronavirus by transmission electron microscopy – a guide to SARS‐CoV‐2‐associated ultrastructural pathology in COVID‐19 tissues
        date: 2020-09-27
       words: 4639
      flesch: 41
     summary: All rights reserved SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States Culture-Based Virus Isolation To Evaluate Potential Infectivity of Clinical Specimens Tested for COVID-19 Detection and Isolation of SARS-CoV-2 in Serum, Urine, and Stool Specimens of COVID-19 Patients from the Republic of Korea Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms Molecular Biology Coronaviruses post-SARS: update on replication and pathogenesis An Overview of Their Replication and Pathogenesis A Novel Coronavirus from Patients with Pneumonia in China Proliferative growth of SARS coronavirus in How COVID-19 spreads Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 Reducing transmission of SARS-CoV-2 Community-Acquired Respiratory Viruses in Transplant Patients: Diversity, Impact, Unmet Clinical Needs SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes Accepted Article
    keywords: article; copyright; coronavirus; covid-19; electron; infection; membrane; patients; replication; sars
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        item: #5850 of 7819
          id: cord-330607-zn4urrxc
      author: Chi, Qiong
       title: Differential diagnosis for suspected cases of coronavirus disease 2019: a retrospective study
        date: 2020-09-18
       words: 3248
      flesch: 44
     summary: Multiplex PCR nucleic acid testing helped differential diagnosis for suspected COVID-19 cases. We retrospectively collected the clinical data, including demographics, clinical manifestations, laboratory and radiological findings and contact history of suspected COVID-19 cases in isolation ward (single rooms) of Wenzhou Central Hospital from January 19, 2020 to February 20, 2020.
    keywords: cases; covid-19; group; nucleic; patients; sars; testing
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        item: #5851 of 7819
          id: cord-330626-0aidit63
      author: Sepulveda, Jorge
       title: Bacteremia and Blood Culture Utilization during COVID-19 Surge in New York City
        date: 2020-07-23
       words: 2700
      flesch: 38
     summary: We sought to evaluate the utilization and diagnostic yield of blood cultures during the COVID-19 pandemic to determine prevalence and common etiologies of bacteremia and to inform a diagnostic approach to relieve blood culture overutilization. Bloodstream infections are very rare for COVID-19 patients, which supports the judicious use of blood cultures in the absence of compelling evidence for bacterial coinfection.
    keywords: bacteremia; blood; covid-19; cultures; days; patients; sars
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        item: #5852 of 7819
          id: cord-330639-1b278jcm
      author: Bandyopadhyay, S.
       title: Infection and mortality of healthcare workers worldwide from COVID-19: a scoping review
        date: 2020-06-05
       words: 6858
      flesch: 53
     summary: There are no studies that examine COVID-19 infection and death amongst HCWs globally. Nurses were the largest HCW group with COVID-19 infection (38.6% of those infected).
    keywords: author; covid-19; data; deaths; hcws; health; license; medrxiv; medrxiv preprint; perpetuity; preprint; review
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        item: #5853 of 7819
          id: cord-330640-6ityxc64
      author: Gupta, Ashim
       title: Mesenchymal stem cells and exosome therapy for COVID-19: current status and future perspective
        date: 2020-08-11
       words: 5166
      flesch: 33
     summary: pneumonia Treatment of acute respiratory distress syndrome with allogeneic adiposederived mesenchymal stem cells: a randomized, placebo-controlled pilot study Immunomodulatory effect of mesenchymal stem cells in chemical-induced liver injury: a high-dimensional analysis Significantly enhanced recovery of acute liver failure by liver targeted delivery of stem cells via heparin functionalization Mesenchymal stem cells increase expression of heme oxygenase-1 leading to anti-inflammatory activity in treatment of acute liver failure Mesenchymal stem cell treatment attenuates liver and lung inflammation after ethanol intoxication and burn injury Extracellular vesicles: novel mediators of cell communication in metabolic disease Immune regulatory targets ofmesenchymal stromal cell exosomes/ small extracellular vesicles in tissue regeneration Exosomes: Looking back three decades and into the future Exosomes: biogenesis, biologic function and clinical potential Mesenchymal stem cell-derived extracellular vesicles for the treatment of acute respiratory distress syndrome: Concise review Review article mesenchymal stem cellbased immunomodulation: properties and clinical application Therapeutic use of extracellular vesicles for acute and chronic lung disease Exosomal microRNAs derived from umbilical mesenchymal stem cells inhibit hepatitis C virus infection The biology of extracellular vesicles: The known unknowns Advances in analysis of biodistribution of exosomes by molecular imaging Emerging potential of exosomes for treatment of traumatic brain injury mechanisms underlying cell therapy for TBI MSC-derived exosome as a novel therapy for TBI Mesenchymal stem cell derived extracellular vesicles ameliorate kidney injury in aristolochic acid nephropathy Exosomes in respiratory disease Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virusinduced acute lung injury in a pig model Conflict of interest The authors declare that they have no conflict of interest. Stem cell -based therapy for coronavirus disease 2019 Transplantation of ACE2 -Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia Primer cytokine storms: understanding COVID-19 The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID -19 infection: the contribution of inlame -aging Care for Critically Ill Patients With COVID-19 Mesenchymal stem cells in the fight against viruses: face to face with the invisible enemy Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Bioinspired engineering for liver tissue regeneration and development of bioartificial liver: A review Stem cell therapy: a hope business or a magic wand? Mesenchymal stem cells modulate the immune system in developing therapeutic interventions Human umbilical cord-derived mesenchymal stem cells in acute liver injury: hepatoprotective efficacy, subchronic toxicity, tumorigenicity, and biodistribution Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial Regenerative abilities of mesenchymal stem cells through mitochondrial transfer Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord mesenchymal stem cells Typical' acute respiratory distress syndrome Immunosuppressive properties of mesenchymal stem cells: advances and applications Immunomodulation by mesenchymal stem cells and clinical experience Current status of potential therapeutic candidates for the COVID-19 crisis Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2 -dependent regulatory dendritic cell population Neoplastic differentiation: interaction of simian virus 40 and polyoma virus with murine teratocarcinoma Neither human immunodeficiency virus-1 (HIV-1) nor HIV-2 infects most-primitive human hematopoietic stem cells as assessed in long-term bone marrow cultures Ex vivo virotherapy with myxoma virus does not impair hematopoietic stem and progenitor cells Embryonic stem cells use ZFP809 to silence retroviral DNAs Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA IFITM-family proteins: the cell's first line of antiviral defense charles Stem cells intrinsic immunity shapes viral resistance of stem cells Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo Activation of human mesenchymal stem cells impacts their therapeutic abilities in lung injury by increasing interleukin ( IL ) -10 and IL-1RN levels Mesenchymal stem cells reconditioned in their own serum exhibit augmented therapeutic properties in the setting of acute respiratory distress syndrome Clinical study of mesenchymal stem cell treating acute respiratory distress syndrome induced by epidemic Inluenza A (H7N9) infection: A hint for COVID-19 treatment.
    keywords: acute; ards; cells; covid-19; exosomes; mesenchymal; mscs; patients; stem; studies; treatment
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        item: #5854 of 7819
          id: cord-330641-pxvc2nw5
      author: Sanchis-Gomar, Fabian
       title: Should atrial fibrillation be considered a cardiovascular risk factor for a worse prognosis in COVID-19 patients?
        date: 2020-07-20
       words: 625
      flesch: 43
     summary: key: cord-330641-pxvc2nw5 authors: Sanchis-Gomar, Fabian; Perez-Quilis, Carme; Lavie, Carl J title: Should atrial fibrillation be considered a cardiovascular risk factor for a worse prognosis in COVID-19 patients? date: 2020-07-20 journal: In effect, some forms of arrhythmia were present in 60% of 85 fatal cases, which suggests that cardiac arrhythmia is associated with an increased risk of mortality in COVID-19 patients.
    keywords: covid-19; patients
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        item: #5855 of 7819
          id: cord-330655-crfj5adf
      author: Haider, Asim
       title: COVID-19 and the Brain: Acute Encephalitis as a Clinical Manifestation
        date: 2020-10-03
       words: 1607
      flesch: 39
     summary: Clinical features of COVID-19 in elderly patients: a comparison with young and middle-aged patients Possible central nervous system infection by SARS coronavirus Nervous system involvement after infection with COVID-19 and other coronaviruses First case of 2019 novel coronavirus disease with encephalitis Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus interaction, and proposed neurotropic mechanisms COVID-19: consider cytokine storm syndromes and immunosuppression How to carry out and interpret EEG recordings in COVID-19 patients in ICU? Brain MRI findings in patients in the intensive care unit with COVID-19 infection Neurologic features in severe SARS-CoV-2 infection Brain MRI findings in severe COVID-19: a retrospective observational study SARS-CoV-2-associated acute hemorrhagic, necrotizing encephalitis (AHNE) presenting with cognitive impairment in a 44-year-old woman without comorbidities: a case report Patients with severe symptoms are more likely to develop neurological symptoms than patients with mild or moderate disease [3] .
    keywords: acute; covid-19; disease; encephalitis; patients
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        item: #5856 of 7819
          id: cord-330656-y6m47tq4
      author: Seo, Eunhye
       title: Fighting the COVID-19 pandemic: onsite mass workplace testing for COVID-19 in the Republic of Korea
        date: 2020-07-02
       words: 840
      flesch: 51
     summary: Alongside onsite COVID-19 examinations, we believe the following issues must be discussed further. Third, we need to focus on the fact that onsite COVID-19 testing can serve as job fitness evaluations.
    keywords: covid-19; system; workers
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        item: #5857 of 7819
          id: cord-330658-vp8fcy1a
      author: Hale, Molly
       title: Outbreak Investigation of COVID-19 in Hospital Food Service Workers
        date: 2020-08-13
       words: 1104
      flesch: 41
     summary: A total of 640 tests were performed in asymptomatic staff. Asymptomatic testing of 280 staff was pursued to provide a more complete estimate of the incidence of disease, the extent of the outbreak, and to evaluate the impact of mitigation measures put in place.
    keywords: covid-19; investigation; staff; testing
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        item: #5858 of 7819
          id: cord-330676-urr9oqfc
      author: Keny, Dr Swapnil
       title: Emergency and Urgent Orthopaedic Surgeries in non covid patients during the COVID 19 pandemic: Perspective from India
        date: 2020-05-12
       words: 2212
      flesch: 44
     summary: Surgical patients may be classified into three risk categories for COVID-19: confirmed and suspected patients, high-risk patients, and low-risk patients (11) . Aligning the interests of clinicians, patients, hospital and government policy makers can be especially difficult (1, 2) .
    keywords: covid; covid-19; emergency; patients; surgeries; surgery
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        item: #5859 of 7819
          id: cord-330701-k68b0wqe
      author: Gerc, Vjekoslav
       title: Cardiovascular Diseases (CVDs) in COVID-19 Pandemic Era
        date: 2020-06-17
       words: 5524
      flesch: 45
     summary: Patients with CVDs must be observed by health professionals (specialists of cardiology, family practitioners, epidemiologists, etc) with special preventive measures regarding COVID-19 infection (1). A Review Effective treatment of severe COVID-19 patients with tocilizumab TH17 responses in cytokine storm of CO-VID-19: an emerging target of JAK2 inhibitor fedratinib COVID-19: consider cytokine storm syndromes and immunosuppression Flooded by the torrent: the COVID-19 drug pipeline Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial ESC Guidance for the Diagnosis and Management of CV Disease during the COVID-19 Pandemic Sleep and Motion Disorders of Physicians and Nurses Working in Hospitals Facing the Pandemic of COVID-19 Pharmacologist's view of the new corona virus
    keywords: cells; covid-19; disease; heart; hypertension; infection; patients; sars; storm; system; virus
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        item: #5860 of 7819
          id: cord-330711-y65csypc
      author: Zimmerer, Karl S.
       title: Informal food chains and agrobiodiversity need strengthening—not weakening—to address food security amidst the COVID-19 crisis in South America
        date: 2020-07-15
       words: 2509
      flesch: 33
     summary: key: cord-330711-y65csypc authors: Zimmerer, Karl S.; de Haan, Stef title: Informal food chains and agrobiodiversity need strengthening—not weakening—to address food security amidst the COVID-19 crisis in South America date: 2020-07-15 journal: Food Secur DOI: 10.1007/s12571-020-01088-x sha: doc_id: 330711 cord_uid: y65csypc The COVID-19 crisis is worsening food insecurity by undermining informal food chains. Our results detail three links of informal food chains that are being disrupted and yet can offer resilience.
    keywords: agrobiodiversity; chains; covid-19; food; security; seed; systems
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        item: #5861 of 7819
          id: cord-330717-uzrxtgrg
      author: Gupta, Madhu
       title: The need for COVID-19 research in low- and middle-income countries
        date: 2020-07-01
       words: 1847
      flesch: 36
     summary: key: cord-330717-uzrxtgrg authors: Gupta, Madhu; Wahl, Brian; Adhikari, Binita; Bar-Zeev, Naor; Bhandari, Sudip; Coria, Alexandra; Erchick, Daniel J.; Gupta, Nidhi; Hariyani, Shreya; Kagucia, E. Wangeci; Killewo, Japhet; Limaye, Rupali Jayant; McCollum, Eric D.; Pandey, Raghukul; Pomat, William S.; Rao, Krishna D.; Santosham, Mathuram; Sauer, Molly; Wanyenze, Rhoda K.; Peters, David H. title: The need for COVID-19 research in low- and middle-income countries date: 2020-07-01 journal: Glob Health Res Policy DOI: 10.1186/s41256-020-00159-y sha: doc_id: 330717 cord_uid: uzrxtgrg In the early months of the pandemic, most reported cases and deaths due to COVID-19 occurred in high-income countries. Some bilateral, multilateral, and private funders have already committed to supporting COVID-19 research in LMICs [10] .
    keywords: countries; covid-19; health; lmics; research
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        item: #5862 of 7819
          id: cord-330728-tul659fr
      author: Zaed, Ismail
       title: How is COVID-19 going to affect education in neurosurgery? A step toward a new era of educational training
        date: 2020-06-11
       words: 1540
      flesch: 42
     summary: In more recent times, VR technologies started to be used also 124 in surgical fields, allowing an enhanced training of surgical skills. 125 It is possible to imagine that in a near future, virtual meeting platforms can be combined with VR 136 technology to provide participants with a real-time feel compared to watching a screen, improving different 137 aspects of the meetings, such as watching live surgeries, being able to interact with the surgical team.
    keywords: covid-19; learning; technology; training
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        item: #5863 of 7819
          id: cord-330755-7kvaduoq
      author: McMahon, Meghan
       title: Informing Canada's Health System Response to COVID-19: Priorities for Health Services and Policy Research
        date: 2020-08-17
       words: 3902
      flesch: 31
     summary: Research is needed to analyze how the healthcare workforce was deployed and supported to provide COVID-19 care, understand the facilitators and barriers to a coordinated and effective response (Basky 2020; Coccolin et al. 2020; Fraher et al. 2020; Lake 2020) , evaluate the impacts on COVID-19 and non-COVID-19 care, and consider the strategies and policies that could be implemented to improve workforce planning, capacity and safety. Priorities need to be established through understanding the experience and perspectives of the public and patients with the pandemic, the COVID-19 and non-COVID-19 care received (or not received), caregiver needs and supports and the supports and tools needed as the crisis subsides (e.g., mental health supports and spiritual care).
    keywords: care; cihr; covid-19; health; healthcare; pandemic; policy; priorities; research; response
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        item: #5864 of 7819
          id: cord-330758-0mdn06qh
      author: Gibson Miller, Jilly
       title: Capability, opportunity, and motivation to enact hygienic practices in the early stages of the COVID‐19 outbreak in the United Kingdom
        date: 2020-05-16
       words: 3279
      flesch: 39
     summary: Strong effects of simple plans Implementation intentions and goal achievement: A metaanalysis of effects and processes The compendium of self-enactable techniques to change and self-manage motivation and behaviour vol 1.0 Using Behavioural Science to Help Fight the Coronavirus Monitoring the psychological impact of the COVID-19 pandemic in the general population: an overview of the context, design and conduct of the COVID-19 Psychological Research Consortium (C19PRC) Study The Behaviour change wheel: a guide to designing interventions Behavioural science must be at the heart of the public health response to covid-19 The Behaviour Change Wheel: a new method for characterizing and designing behaviour change interventions Anxiety, depression, traumatic stress, and COVID-19 related anxiety in the UK general population during the COVID-19 Pandemic Using social and behavioural science to support COVID-19 pandemic response Achieving behaviour change: A guide for local government and partners Supporting Information Behaviour change interventions to improve and maintain hygienic practices throughout the lockdown and beyond should contain behaviour change techniques that focus on self-regulatory processes involving planning and goal setting.
    keywords: behaviour; change; com; covid-19; hygienic; motivation; practices
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        item: #5865 of 7819
          id: cord-330786-52xyuwum
      author: Jones, C. M.
       title: Considerations for the Treatment of Oesophageal Cancer With Radiotherapy During the COVID-19 Pandemic
        date: 2020-04-09
       words: 2085
      flesch: 34
     summary: Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia SARS-CoV-2 transmission in patients with cancer at a tertiary care hospital in Wuhan, China Cancer patients in SARS-Co-V-2 infection: a nationwide analysis in China Risk of COVID-19 for cancer patients Letter from Italy: first practical indications for radiation therapy departments during COVID-19 outbreak Clinical guide for the management of cancer patients during the coronavirus pandemic COVID-19: global radiation oncology's targeted response for pandemic preparedness Definitive chemoradiotherapy for oesophageal cancer e a promising start on an exciting journey Chemoradiotherapy with or without cetuximab in patients with oesophageal cancer (SCOPE1): a multicenter, phase 2/3 randomised trial Longterm results and recurrence patterns from SCOPE-1: a phase II/ III randomized trial of definitive chemoradiotherapy AE cetuximab in oesophageal cancer Acute toxicity of definitive chemoradiation in patients with inoperable or irresectable esophageal carcinoma In light of this we convened an expert group of UK clinicians with expertise in oesophageal cancer.
    keywords: cancer; covid-19; patients; radiotherapy; treatment
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        item: #5866 of 7819
          id: cord-330788-2wsn8t2r
      author: Zhang, Caiyun
       title: The Psychological Impact of the COVID-19 Pandemic on Teenagers in China
        date: 2020-10-08
       words: 4804
      flesch: 44
     summary: Moderate depressive symptoms were found in 9.1% of junior high school students and 6.8% of high school students, and severe-to-extremely severe depressive symptoms were found in 5.3% of junior high school students and 2.6% of high school students, with no significant between-group difference (c 2 ¼ 4.33; p ¼ .363). Moderate anxiety symptoms were found in 10.3% of junior high school students and 10.9% of high school students, and severe-to-extremely severe anxiety symptoms were found in 10.0% of junior high school students and 7.2% of high school students, with a significant betweengroup difference (c 2 ¼ 12.33; p ¼ .015).
    keywords: anxiety; coping; resilience; school; school students; stress; students; symptoms
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        item: #5867 of 7819
          id: cord-330792-dxdpn46t
      author: Moulson, Nathaniel
       title: Cardiac Rehabilitation during the COVID-19 Era: Guidance on Implementing Virtual Care
        date: 2020-06-14
       words: 2236
      flesch: 27
     summary: During the initial implementation phases of VCR, centres face possible CR staff redeployment due to COVID-19 related issues, a potential lack of centre and patient experience with virtual care delivery, and uncertain access to affordable, effective technologies. Virtual cardiac rehabilitation (VCR) offers an alternate mechanism of care delivery, capable of providing similar patient outcomes and safety profiles compared to centre-based programs.
    keywords: care; covid-19; programs; rehabilitation; risk; vcr
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        item: #5868 of 7819
          id: cord-330831-3b7vfv9b
      author: Hao, Fengyi
       title: A quantitative and qualitative study on the neuropsychiatric sequelae of acutely ill COVID-19 inpatients in isolation facilities
        date: 2020-10-19
       words: 8243
      flesch: 41
     summary: A greater proportion of COVID-19 patients experienced impulsivity (p = 0.016) and insomnia (p = 0.039) than psychiatric patients and healthy controls. COVID-19 patients reported a higher psychological impact of the outbreak than psychiatric patients and healthy controls, with half of them having clinically significant symptoms of posttraumatic stress disorder.
    keywords: anxiety; covid-19; covid-19 patients; depression; health; impact; infection; isolation; outbreak; pandemic; patients; stress; study; symptoms
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        item: #5869 of 7819
          id: cord-330837-pwwgmtjr
      author: Lim, Zheng Jie
       title: Incidence and outcome of out-of-hospital cardiac arrests in the COVID-19 era: A systematic review and meta-analysis
        date: 2020-11-01
       words: 3369
      flesch: 48
     summary: In this systematic review and meta-analysis, the authors aimed to determine the influence of the COVID-19 pandemic on the incidence, processes of care and mortality among OHCA patients. J o u r n a l P r e -p r o o f DISCUSSION Across the selected studies, we observed a more than two-fold increase in OHCA incidence during the COVID-19 pandemic, with an overall significant increase in mortality.
    keywords: covid-19; cpr; hospital; ohca; pandemic; patients; studies
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        item: #5870 of 7819
          id: cord-330849-yt44k88m
      author: Han, Rachel H.
       title: Planning for Mental Health Needs During COVID-19
        date: 2020-10-08
       words: 5527
      flesch: 35
     summary: Herein, we review data on mental health sequelae from the twenty-first century pandemics, including SARS-CoV2 (COVID-19), and offer explanations for observed trends, insights regarding anticipated needs, and recommendations for preliminary planning on how to best allocate limited mental health resources. Historically, pandemics have had significant ramifications for psychological stress and mental health.
    keywords: anxiety; covid-19; data; depression; distress; health; impact; mental; outbreak; pandemics; review; stress; symptoms
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        item: #5871 of 7819
          id: cord-330869-k5ro0edf
      author: Kumar Singh, Awadhesh
       title: Assessment of risk, severity, mortality, glycemic control and antidiabetic agents in patients with diabetes and COVID-19: A Narrative Review
        date: 2020-06-11
       words: 5036
      flesch: 38
     summary: A Nationwide Analysis of China Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province Clinical features and treatment of COVID-19 patients in northeast Chongqing Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Clinical Features of 69 Cases with Coronavirus Disease Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Clinical Characteristics of Coronavirus Disease 2019 in China Epidemiology Working Group for Ncip Epidemic Response. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 26 2019 -United States Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol Hospitalization and 30-day fatality in 121,263 COVID-19 outpatient cases Predicting mortality due to SARS-CoV-2: A mechanistic score relating obesity and diabetes to COVID-19 outcomes in Mexico Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia -A systematic review, meta-analysis, and meta-regression Diabetes is a risk factor for the progression and prognosis of COVID-19 Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes Clinical course and risk factors or mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese center for disease control and prevention Glycemic Characteristics and Clinical Outcomes of COVID-19 Patients Hospitalized in the United States OpenSAFELY: factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients Clinical considerations for patients with diabetes in times of COVID-19 epidemic Practical recommendation Lancet Diabetes & Endocrinology Diabetes in COVID-19: Prevalence, pathophysiology, prognosis and practical considerations Guidelines for the management of diabetes in care homes during the Covid-19 pandemic COVID-19 and endocrine diseases Our Response to COVID-19 as Endocrinologists and Diabetologists Should anti-diabetic medications be reconsidered amid COVID-19 pandemic?
    keywords: coronavirus; covid-19; diabetes; disease; increase; meta; mortality; patients; prevalence; risk; studies
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        item: #5872 of 7819
          id: cord-330870-l0ryikhv
      author: Eubanks, Allison
       title: Obstetric Simulation for a Pandemic
        date: 2020-07-23
       words: 3233
      flesch: 41
     summary: In the current COVID-19 pandemic, simulating obstetrical patient care from presentation to the hospital triage through postpartum care can prepare teams for even the most complicated patients while increasing their ability to protect themselves and their patients. Conclusion: In the current COVID-19 pandemic, simulating obstetrical patient care from presentation to the hospital triage through postpartum care can prepare teams for even the most complicated patients while increasing their ability to protect themselves and their patients.
    keywords: care; covid-19; pandemic; patients; room; simulation; teams
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        item: #5873 of 7819
          id: cord-330877-nsx4b4rm
      author: Elcioglu, Omer Celal
       title: COVİD-19 infection in a membranous nephropathy patient treated with rituximab
        date: 2020-09-04
       words: 2094
      flesch: 49
     summary: However, clinical studies have shown that ACEi or ARBs do not increase morbidity or mortality in COVID-19 patients [18] [19] [20] . In this period, one of our group of patients who are challenging us for follow-up and treatment are those who should start or continue to use immunosuppressive therapy.
    keywords: covid-19; immunosuppressive; kidney; march; patients; treatment
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        item: #5874 of 7819
          id: cord-330880-6lx66w8h
      author: Nikolopoulos, Konstantinos
       title: Forecasting and planning during a pandemic: COVID-19 growth rates, supply chain disruptions, and governmental decisions
        date: 2020-08-08
       words: 7742
      flesch: 48
     summary: We decided to use auxiliary data as confirmed supply chain demand data will not be available for the months to come and as such no demand modelling would be possible until then. Furthermore, our results illustrate the challenge of making forecasts and making supply chain decisions for products where consumers need to make judgments about their own immediate needs.
    keywords: chain; countries; country; covid-19; data; demand; forecasting; forecasts; lockdown; methods; models; pandemic; products; research; supply; time
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        item: #5875 of 7819
          id: cord-330887-q5i8lpan
      author: Li, K.
       title: The Dynamic Changes of Antibodies against SARS-CoV-2 during the Infection and Recovery of COVID-19
        date: 2020-05-21
       words: 4027
      flesch: 49
     summary: To illustrate the relationship between SARS-COV-2 virus load and antibody levels, we analyzed the test results of patients who tested both virus load and antibody level on the same day and compared the S-, RBD-, and N-specific antibody levels between virus-positive and virus-negative status. Importantly, the patients who got discharged with low levels of protective antibody are found to be at high risk of re-infection, indicating the prognostic role of antibody level for discharged COVID-19 patients.
    keywords: antibody; covid-19; igg; levels; patients; preprint
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        item: #5876 of 7819
          id: cord-330916-s99ayg1j
      author: Hernandez, Adrian V.
       title: Update Alert: Hydroxychloroquine or Chloroquine for the Treatment or Prophylaxis of COVID-19
        date: 2020-07-15
       words: 977
      flesch: 39
     summary: Preprint posted online 16 Association of treatment with hydroxychloroquine or azithromycin with in-hospital mortality in patients with COVID-19 in New York State Hydroxychloroquine and tocilizumab therapy for COVID-19 patients -an observational study. Preprint posted online 2 Early hydroxychloroquine is associated with an increase of survival in COVID-19 patients: an observational study Observational study of hydroxychloroquine in hospitalized patients with covid-19 No evidence of clinical efficacy of hydroxychloroquine in patients hospitalized for COVID-19 infection with oxygen requirement: results of a study using routinely collected data to emulate a target trial.
    keywords: covid-19; hydroxychloroquine; patients
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        item: #5877 of 7819
          id: cord-330918-hsy8h1vb
      author: Song, Jia
       title: A Comparison of Clinical Characteristics and Outcomes in Elderly and Younger Patients with COVID-19
        date: 2020-07-28
       words: 2942
      flesch: 45
     summary: Epidemiological, demographic, clinical, and laboratory data, as well as treatments, complications, and outcomes were extracted from electronic medical records and compared between elderly patients (aged ≥60 years) and younger patients (aged <60 years). Elderly patients had more complications than younger patients, including acute respiratory distress syndrome (ARDS; 9/25, 36% vs. 5/44, 11.4%) and cardiac injury (7/25, 28% vs. 1/44, 2.3%), and they were more likely to be admitted to the intensive care unit (6/25, 24% vs. 2/44, 4.5%).
    keywords: china; clinical; coronavirus; covid-19; patients; study
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        item: #5878 of 7819
          id: cord-330919-dep3v1pt
      author: Whyte, Claire S
       title: Fibrinolytic abnormalities in acute respiratory distress syndrome (ARDS) and versatility of thrombolytic drugs to treat COVID‐19
        date: 2020-04-23
       words: 4261
      flesch: 30
     summary: A Case Series Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism Tissue plasminogen activator (tPA) inhibits interleukin-1 induced acute lung leak Heuze-Vourc'h N. Designing inhaled protein therapeutics for topical lung delivery: what are the next steps? Effects of nebulized antithrombin and heparin on inflammatory and coagulation alterations in an acute lung injury model in rats Aerosolized anticoagulants ameliorate acute lung injury in sheep after exposure to burn and smoke inhalation Heparin nebulization attenuates acute lung injury in sepsis following smoke inhalation in sheep Nebulized anticoagulants in lung injury in critically ill patients-an updated systematic review of preclinical and clinical studies Streptokinase Versus Unfractionated Heparin Nebulization in Patients With Severe Acute Respiratory Distress Syndrome (ARDS): PAR signalling can enhance inflammation in acute lung injury (ALI) by increasing the expression of pro-inflammatory cytokines, including IL-6
    keywords: acute; ards; covid-19; distress; fibrin; injury; lung; patients; plasminogen; syndrome
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        item: #5879 of 7819
          id: cord-330936-qf4q8yqq
      author: Kardeş, Sinan
       title: Public interest in rheumatic diseases and rheumatologist in the United States during the COVID-19 pandemic: evidence from Google Trends
        date: 2020-10-18
       words: 2830
      flesch: 29
     summary: A position statement from APLAR Risk factors for hospital admissions related to COVID-19 in patients with autoimmune inflammatory rheumatic diseases Determinants of COVID-19 disease severity in patients with underlying rheumatic disease Aktay Ayaz N (2020) Does immunosuppressive treatment entail an additional risk for children with rheumatic diseases? key: cord-330936-qf4q8yqq authors: Kardeş, Sinan; Kuzu, Ali Suat; Raiker, Rahul; Pakhchanian, Haig; Karagülle, Mine title: Public interest in rheumatic diseases and rheumatologist in the United States during the COVID-19 pandemic: evidence from Google Trends date: 2020-10-18 journal: Rheumatol Int DOI: 10.1007/s00296-020-04728-9 sha: doc_id: 330936 cord_uid: qf4q8yqq To evaluate the public interest in rheumatic diseases during the coronavirus disease 2019 (COVID-19) pandemic.
    keywords: covid-19; disease; interest; period; search; trends
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        item: #5880 of 7819
          id: cord-330975-2tome934
      author: Pilato, Emanuele
       title: Pulmonary embolism and Sars-Cov-2 infection: a new indication for surgical pulmonary endarterectomy?
        date: 2020-05-18
       words: 426
      flesch: 38
     summary: Nowadays, chronic pulmonary embolism can be effectively treated with medical therapy but in some limited cases it can require a surgical treatment Surgery for chronic pulmonary embolism is a very rare but challenging situation because it requires long surgical times and sometimes the need to deep hypothermia and circulatory arrest [4].
    keywords: patients; pulmonary
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        item: #5881 of 7819
          id: cord-330998-ttwadtay
      author: Petersen, Fernanda Cristina
       title: COVID-19: Looking Into the Overlooked
        date: 2020-08-11
       words: 1863
      flesch: 26
     summary: Other reports indicate that bacterial infections were documented in <10% of COVID-19 patients (Zhou P. et al., 2020) . Indeed, we have recently learnt that particular blood groups (group A) may be linked to respiratory failure in COVID-19 patients (Ellinghaus et al., 2020) .
    keywords: covid-19; infections; microbiota; patients
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        item: #5882 of 7819
          id: cord-331030-3icwei3e
      author: Saleknezhad, N.
       title: COVID-19 and heart medications: What's the connection?
        date: 2020-08-26
       words: 2728
      flesch: 52
     summary: For instance, statins and angiotensin receptor blockers (ARBs) may actually worsen the outcome of COVID-19 patients, who, due to their underlying diseases, have poorer prognosis [6] . Therefore, we conducted a study based on our registry of COVID-19 patients to evaluate the effect of those drugs, which are widely used in chronic diseases such as hypertension, diabetes mellitus and ischemic heart disease, on the clinical outcome and mortality rate of the patients inflicted with the novel coronavirus.
    keywords: author; covid-19; funder; medrxiv; patients; preprint
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        item: #5883 of 7819
          id: cord-331046-440kruco
      author: Culp, Brian M.
       title: COVID-19 Impact on Young Arthroplasty Surgeons
        date: 2020-04-24
       words: 2461
      flesch: 49
     summary: Finally, we assessed early practice surgeons regarding compensation and employment status, as well as advancement in career stage/partner/tenure, modification of practice nature to cover medical patients/COVID-19 patients, and further implications within payment models and future job opportunities. Employed young surgeons are in a similar situation, as opposed to private practice surgeons.
    keywords: compensation; covid-19; orthopaedic; practice; surgeons
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        item: #5884 of 7819
          id: cord-331055-5ni0jxij
      author: Bouche, Pierre-Alban
       title: Were protective procedures against SARS-CoV-2 effective in an orthopaedic and trauma centre during the lockdown period? A retrospective study
        date: 2020-07-16
       words: 2377
      flesch: 48
     summary: Patients included were those who had surgery during the lockdown period. To allow the effectiveness of the procedures implemented, we evaluated the number of complications attributed to SARS-CoV-2 and the number of patients who became COVID positive during hospitalization.
    keywords: complications; covid-19; lockdown; patients; procedures
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        item: #5885 of 7819
          id: cord-331058-ou6vqp7n
      author: Chireh, Batholomew
       title: Leveraging best practices: protecting sub-Saharan African prison detainees amid COVID-19
        date: 2020-06-24
       words: 1650
      flesch: 48
     summary: Similar conditions are common and conducive for COVID-19 spread in most African prisons given the poor infrastructure of prisons in the region. Health data from African prisons differed by regional blocks.
    keywords: covid-19; health; prisoners; prisons
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        item: #5886 of 7819
          id: cord-331060-b3z1zb4t
      author: Cruickshank, Marilyn
       title: COVID‐19: Lessons to be learnt from a once‐in‐a‐century global pandemic
        date: 2020-06-04
       words: 2293
      flesch: 49
     summary: A better understanding of, and resolution to, the barriers to recognition of nurse leaders in events like these, in particular those in infection prevention and control, is also required given that outbreaks of infectious diseases are here to stay and the fundamental role that nurses play in outbreak responses now and into the future. The outbreaks of SARS-CoV-1, MERS-CoV, Ebola and H1N1, and the lessons learned from each have been noteworthy: importance of good hygiene (hands and surroundings), testing when possible, isolation of those infected, personal protection equipment for health care workers and others involved in the care of the infected, expurgated search for treatments, and vaccines.
    keywords: covid-19; health; infection; outbreak; pandemic; spread
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        item: #5887 of 7819
          id: cord-331065-tzvkj2rm
      author: Terracciano, Antonio
       title: Changes in Subjective Age During COVID-19
        date: 2020-08-07
       words: 5695
      flesch: 49
     summary: Daily health, stressors, and affect explain day-to-day variability in subjective age Countries and cultural differences in the stigma of mental illness: The east-west divide The trajectory of loneliness in response to COVID-19 Reducing ageism: Education about aging and extended contact with older adults You're only as old as you feel: Selfperceptions of age, fears of aging, and life satisfaction from adolescence to old age Video calls for reducing social isolation and loneliness in older people: a rapid review Patients Dying in Relation to COVID-19 in Italy Subjective age and perceived distance-to-death moderate the association between posttraumatic stress symptoms and posttraumatic growth among older adults Understanding the long-term connections between posttraumatic stress, subjective age, and successful aging among midlife and older adults HLM (Version 6) Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Is the relationship between subjective age, depressive symptoms and activities of daily living bidirectional? People over forty feel 20% younger than their age: Subjective age across the lifespan Development of the 12-item expectations regarding aging survey Age identity in context: Stress and the subjective side of aging Feeling younger, being stronger: An experimental study of subjective age and physical functioning among older adults Subjective age and changes in memory in older adults How old do you feel? To examine change in subjective age with the emergence of coronavirus disease 2019 (COVID-19).
    keywords: adults; age; aging; covid-19; subjective; wave
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        item: #5888 of 7819
          id: cord-331075-27ndnqzv
      author: Oleribe, Obinna O
       title: COVID-19 Experience: Taking the Right Steps at the Right Time to Prevent Avoidable Morbidity and Mortality in Nigeria and Other Nations of the World
        date: 2020-08-04
       words: 2070
      flesch: 46
     summary: Doctors, nurses, pharmacies, laboratory scientists, community health workers, and support staff should be mobilized to volunteer as frontline workers to manage the DIT centers in each location. The response to the pandemic is with a healthcare system that has changed as a result of previous infectious disease outbreaks but in the context of scarce resources typical of many low-middle income countries.
    keywords: cases; covid-19; nigeria; outbreak; pandemic; workers
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        item: #5889 of 7819
          id: cord-331087-kpze9xux
      author: Siddiqui, S.
       title: SARS-CoV-2 antibody seroprevalence and stability in a tertiary care hospital-setting
        date: 2020-09-03
       words: 3248
      flesch: 46
     summary: With the rapid increase in the number of confirmed COVID-19 cases, India remains one of the severely affected countries with on-going pandemic. They have reported the presence of antibodies among the asymptomatic individuals along with confirmed COVID-19 cases.
    keywords: antibodies; cov-2; covid-19; individuals; population; sars; study
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        item: #5890 of 7819
          id: cord-331092-eocse0xa
      author: Gowrisankar, A.
       title: Can India develop herd immunity against COVID-19?
        date: 2020-06-26
       words: 2248
      flesch: 51
     summary: In general, epidemiological analysis models assume that the number of confirmed positive cases of COVID-19 grows exponentially with respect to fixed reproduction rate n. Each person infected by the COVID-19 transmits to n number of new persons when n > 1, and then the total number of COVID-19 cases grows as n t τ Hence, this paper applies multifractal formalism on COVID-19 data with the notion that country-specific infection rates follow a power law growth behaviour.
    keywords: countries; covid-19; data; fractal; growth; india
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        item: #5891 of 7819
          id: cord-331094-22366b81
      author: Ianevski, Aleksandr
       title: Potential Antiviral Options against SARS-CoV-2 Infection
        date: 2020-06-13
       words: 6839
      flesch: 43
     summary: The convalescent sera option for containing COVID-19 Effectiveness of convalescent plasma therapy in severe COVID-19 patients Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma The Roles of Host and Viral Antibody Fc Receptors in Herpes Simplex Virus (HSV) and Human Cytomegalovirus (HCMV) Infections and Immunity Fc-Mediated Antibody Effector Functions During Respiratory Syncytial Virus Infection and Disease A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus Discovery and development of safe-in-man broad-spectrum antiviral agents Novel activities of safe-in-human broad-spectrum antiviral agents Human induced pluripotent stem cells are a novel source of neural progenitor cells (iNPCs) that migrate and integrate in the rodent spinal cord (BOMB): Open platform for high-throughput nucleic acid extraction and manipulation Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection Obatoclax, saliphenylhalamide and gemcitabine inhibit Zika virus infection in vitro and differentially affect cellular signaling, transcription and metabolism Expanding the activity spectrum of antiviral agents SynergyFinder 2.0: Visual analytics of multi-drug combination synergies DrugCentral 2018: These results are consistent with previous studies showing that physical factors destabilize SARS-CoV-2 and other viruses [39] [40] [41] [42] .
    keywords: amodiaquine; antiviral; cells; compounds; cov-2; covid-19; drug; figure; infection; nelfinavir; patients; samples; sars; serum; treatment; vero; virus
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        item: #5892 of 7819
          id: cord-331105-wdkdc0pw
      author: Baral, Stefan David
       title: The Public Health Response to COVID-19: Balancing Precaution and Unintended Consequences
        date: 2020-05-08
       words: 1681
      flesch: 27
     summary: As data to inform a more strategic approach emerge, however, we must begin to move from a precautionary position to one that also considers the proportionality and specificity of the public health response, with the overall goal of maximizing population health. Controlling infectious disease outbreaks: Lessons from mathematical modelling Differential effects of pandemic (H1N1) 2009 on remote and indigenous groups Virus genomes reveal factors that spread and sustained the Ebola epidemic The disconnect between individual-level and population-level HIV prevention benefits of antiretroviral treatment A critique of Geoffrey Rose's 'population strategy' for preventive medicine Where Have All the Heart Attacks Gone? Poverty and Child Health in the United States Health system, public health, and economic implications of managing COVID-19 from a cardiovascular perspective Not a luxury: a call to maintain sexual and reproductive health in humanitarian and fragile settings during the COVID-19 pandemic On the Limits of the Precautionary Principle
    keywords: covid-19; health; models; pandemic; response
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        item: #5893 of 7819
          id: cord-331109-a8e7r80d
      author: Ibrahim, Yassmin S.
       title: Case Report: Paralytic Ileus: A Potential Extrapulmonary Manifestation of Severe COVID-19
        date: 2020-08-31
       words: 2365
      flesch: 42
     summary: Moreover, Bhayana et al. 20 reported bowel wall abnormalities in 31% of abdominal CT scan images in COVID-19 patients, including pneumatosis and portal venous gas. Therefore, this could be a potential mechanism of paralytic ileus in severe COVID-19 cases.
    keywords: bowel; cases; covid-19; ileus; infection; patients; sars
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        item: #5894 of 7819
          id: cord-331114-lumfg138
      author: Berkman, Samuel A
       title: Methodological Issues and Controversies in COVID-19 Coagulopathy: A Tale of Two Storms
        date: 2020-09-03
       words: 6284
      flesch: 38
     summary: This strategy is reinforced by the low incidence of bleeding observed in COVID patients compared with other causes of DIC such as obstetrical ones. While the major bleeding in trials involving COVID patients thus far appears to be low, full-dose anti-coagulation in such ill patients is not benign.
    keywords: anti; coagulation; covid; covid-19; cytokine; dose; hydroxychloroquine; patients; storm; thrombosis; trial; venous
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        item: #5895 of 7819
          id: cord-331120-bp1obxd4
      author: Ho, B.
       title: A Case for Palliative Dermatology: COVID-19-related Dermatoses()()
        date: 2020-06-05
       words: 635
      flesch: 34
     summary: In the United Kingdom, various subspecialties were deployed to the wards to help medical workforce in the frontlines, with dermatologists helping with general medical wards and on-calls. In the United Kingdom, various subspecialties were deployed to the wards to help medical workforce in the frontlines, with dermatologists helping with general medical wards and on-calls.
    keywords: covid-19; dermatology
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        item: #5896 of 7819
          id: cord-331130-vr8kczes
      author: Chirico, Francesco
       title: Hospital infection and COVID-19: Do not put all your eggs on the “swab” tests
        date: 2020-05-27
       words: 780
      flesch: 39
     summary: Finally, a policy of universal masking and eye shielding for all healthcare providers involved in direct patient care is needed. key: cord-331130-vr8kczes authors: Chirico, Francesco; Nucera, Gabriella; Magnavita, Nicola title: Hospital infection and COVID-19: Do not put all your eggs on the “swab” tests date: 2020-05-27 journal: Infection control and hospital epidemiology DOI: 10.1017/ice.2020.254 sha: doc_id: 331130 cord_uid: vr8kczes nan To the Editor-In healthcare settings, including long-term care facilities, hospital administrators have a legal obligation to set up a risk assessment strategy to carry out effective prevention and control measures during the management of suspected and confirmed cases of COVID-19 infection.
    keywords: covid-19; patients; swab
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        item: #5897 of 7819
          id: cord-331135-4u99yxw2
      author: Arsandaux, J.
       title: Higher risk of mental health deterioration during the Covid-19 lockdown among students rather than non-students. The French Confins study
        date: 2020-11-05
       words: 4657
      flesch: 42
     summary: The Lancet The psychological impact of the COVID-19 epidemic on college students in China Depression, anxiety and stress in different subgroups of first-year university students from 4-year cohort data Depression and Anxiety in Hong Kong during COVID-19 The Mental Health Consequences of COVID-19 and Physical Distancing: The Need for Prevention and Early Intervention Social support and protection from depression: systematic review of current findings in Western countries COVID-19) in Spain Effects of Covid-19 Lockdown on Mental Health and Sleep Disturbances in Italy Mental Health Problems and Help-Seeking Behavior Among College Students Stress and anxiety among university students in France during Covid-19 mandatory confinement A systematic review of studies of depression prevalence in university students Missing covariate data in medical research: to impute is better than to ignore Age of onset of mental disorders: A review of recent literature Rules on isolation rooms for suspected covid-19 cases in GP surgeries to be relaxed Mental health of college students and their non-college-attending peers: Results from a large French cross-sectional survey The PHQ-9 Optimal cut-off score for diagnosing depression with the Patient Health Questionnaire (PHQ-9): a meta-analysis A Nationwide Survey of Psychological Distress among Italian People during the COVID-19 Pandemic: Immediate Psychological Responses and Associated Factors Rapid detection of generalized anxiety disorder and major depression in epilepsy: Validation of the GAD-7 as a complementary tool to the NDDI-E in a French sample Psychological effects of the COVID-19 outbreak and lockdown among students and workers of a Spanish university Psychological Symptoms During the Two Stages of Lockdown in Response to the COVID-19 Outbreak: An Investigation in a Sample of Citizens in Northern Spain Patient health questionnaire (PHQ) screeners Especially psychological support could be provided by University health student services both online and through crisis hotlines.
    keywords: covid-19; health; lockdown; preprint; students; symptoms
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        item: #5898 of 7819
          id: cord-331143-e9h7tq0x
      author: Singh, Manish Kumar
       title: Contagion effect of COVID‐19 outbreak: Another recipe for disaster on Indian economy
        date: 2020-05-27
       words: 2897
      flesch: 54
     summary: COVID-19 does not only bring health sector crisis to the world but also assign economic crisis. Thus the poor health facilities in India are clearly visible form the above discussion and this pandemic will be a challenging time for Indian health sector.
    keywords: covid-19; economic; economy; government; health; india; sector; world
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        item: #5899 of 7819
          id: cord-331155-jkm4fuw4
      author: Nakashima, Akiko
       title: Virus database annotations assist in tracing information on patients infected with emerging pathogens
        date: 2020-10-08
       words: 3873
      flesch: 36
     summary: Kyoto Encyclopedia of Genes and Genomes Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains The Protein Data Bank Protein Identification and Analysis Tools in the ExPASy Server Coronaviruses: an RNA proofreading machine regulates replication fidelity and diversity Celebrating wobble decoding: Half a century and still much is new Geographic and Genomic Distribution of SARS-CoV-2 Variant analysis of SARS-cov-2 genomes A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury Understanding Human Coronavirus HCoV-NL63 Cryo-EM analysis of a feline coronavirus spike protein reveals a unique structure and camouflaging glycans Insights into changes in binding affinity caused by disease mutations in protein-protein complexes Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 Comment Improving epidemic surveillance and response : big data is dead , long live big data A real-time dashboard of clinical trials for COVID-19 Antibodies and vaccines against Middle East respiratory syndrome coronavirus A human monoclonal antibody blocking SARS-CoV-2 infection Discovering drugs to treat coronavirus disease 2019 (COVID-19) We propose the use of additional annotation tags for patients that are anonymized with maximum privacy protection and informed consent on sampling virus genetic data around the world without borders.
    keywords: analysis; coronavirus; cov-2; covid-19; data; protein; r n; sars; virus
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        item: #5900 of 7819
          id: cord-331165-2yn1n3eq
      author: Tauben, David J.
       title: Optimizing telehealth pain care after COVID-19
        date: 2020-08-20
       words: 5918
      flesch: 23
     summary: management A crisis in chronic pain care: an ethical analysis. The effectiveness of exercise-based telemedicine on pain, physical activity and quality of life in the treatment of chronic pain: a systematic review Improving pain care with Project ECHO in community health centers Cognitive-behavioral-based physical therapy for patients with chronic pain undergoing lumbar spine surgery: a randomized controlled trial Australian Government Department of Health.
    keywords: access; care; covid-19; management; pain; pain management; patient; person; providers; review; services; systematic; telehealth; treatment
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        item: #5901 of 7819
          id: cord-331193-33cyvidx
      author: Mawhinney, Jamie A
       title: Neurotropism of SARS-CoV-2: COVID-19 presenting with an acute manic episode
        date: 2020-06-14
       words: 2522
      flesch: 45
     summary: Investigations confirmed that he was positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Investigations confirmed that he was positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
    keywords: acute; case; coronavirus; cov-2; covid-19; history; sars
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        item: #5902 of 7819
          id: cord-331206-m938suxh
      author: Rodgers, F.
       title: Missing clinical trial data: the knowledge gap in the safety of potential COVID-19 drugs
        date: 2020-06-03
       words: 4318
      flesch: 41
     summary: However, availability of safety information is limited by a lack of timely reporting of clinical trial results on public registries or through academic publication. Key drugs missing clinical trial results include hydroxychloroquine (37.0% completed trials unreported), favipiravir (77.8%) and lopinavir (40.5%).
    keywords: author; clinicaltrials.gov; covid-19; drugs; license; medrxiv; preprint; results; safety; trials
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        item: #5903 of 7819
          id: cord-331208-bgh1a14p
      author: Garcia, M.
       title: Innate lymphoid cell composition associates with COVID-19 disease severity
        date: 2020-10-14
       words: 3303
      flesch: 51
     summary: To describe the phenotypic landscape of circulating ILCs in COVID-19 patients and to identify ILC phenotypes correlated to serum biomarkers, clinical markers, and laboratory parameters relevant in COVID-19. Results: ILCs were largely depleted from the circulation of COVID-19 patients compared with healthy controls.
    keywords: author; fig; funder; medrxiv; preprint; review
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        item: #5904 of 7819
          id: cord-331230-mp7sdh73
      author: Landy, David C.
       title: Public Interest in Knee Replacement Fell During the Onset of the COVID-19 Pandemic: A Google Trends Analysis
        date: 2020-09-15
       words: 2882
      flesch: 52
     summary: Around the same days that knee replacement searches began to decrease, searches for coronavirus spiked (Fig. 2 ). Surgeons and hospitals face several challenges as elective knee replacements resume after the initial onset of the COVID-19 pandemic.
    keywords: covid-19; knee; pandemic; public; replacement; searches
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        item: #5905 of 7819
          id: cord-331243-0u65qguq
      author: Ucciferri, Claudio
       title: Role of monoclonal antibody drugs in the treatment of COVID-19
        date: 2020-10-06
       words: 1696
      flesch: 33
     summary: A single center experience Off-label use of tocilizumab in patients with SARS-CoV-2 infection Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: A single center study of 100 patients in Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: Results from a single Italian Centre study on tocilizumab versus standard of care Efficacy and safety of tocilizumab in severe COVID-19 patients: a single-centre retrospective cohort study Interleukin-1 in the pathogenesis and treatment of inflammatory diseases Targeting the inflammatory cascade with anakinra in moderate to severe COVID-19 pneumonia: case series Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study Canakinumab in a subgroup of patients with COVID-19 Could ruxolitinib be effective in patients with COVID-19 infection at risk of acute respiratory distress syndrome (ARDS)? The cytokine storms mediated by overproduction of proinflammatory cytokines have been observed in COVID-19 patients [9] .
    keywords: cov-2; covid-19; infection; patients; sars
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        item: #5906 of 7819
          id: cord-331257-z2x1wax0
      author: Yao, Yang
       title: Psychological Status and Influencing Factors of Hospital Medical Staff During the COVID-19 Outbreak
        date: 2020-08-04
       words: 2628
      flesch: 51
     summary: The major demographic, professional characteristics, and psychological distress scores were shown in Table 2 . More than half of the participants (61.1%) reported psychological distress.
    keywords: covid-19; distress; hcws; health; medical; staff
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        item: #5907 of 7819
          id: cord-331273-1fixwxuo
      author: Abejón González, David
       title: How to restart the interventional activity in the COVID‐19 era. The experience of a private Pain Unit in Spain
        date: 2020-09-23
       words: 4436
      flesch: 35
     summary: As the situation continues, the need to reinstate attention for chronic pain patients grows. In the crisis generated by the COVID-19 pandemic, we must agree on the recommendations that guarantee the safety and maintains health care for chronic pain patients.
    keywords: activity; article; chronic; covid-19; infection; opioids; pain; pandemic; patients; recommendations; system; use
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        item: #5908 of 7819
          id: cord-331284-uy6xoltj
      author: Ponzetto, Antonio
       title: COVID-19, coagulopathy and venous thromboembolism: more questions than answers—comment
        date: 2020-09-17
       words: 484
      flesch: 30
     summary: In addition, they compared the neutrophil activation state from severe COVID-19 cases, namely those requiring mechanical ventilation, and from patients with less severe disease who only required oxygen therapy, and observed that neutrophils were highly upregulated in severe cases. Several parameters were reported to associate with microthrombosis and poor prognosis in COVID-19 patients.
    keywords: covid-19; patients
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        item: #5909 of 7819
          id: cord-331328-qom8vl94
      author: Gianfrancesco, Milena A
       title: Rheumatic disease and COVID-19: initial data from the COVID-19 Global Rheumatology Alliance provider registries
        date: 2020-04-16
       words: 1419
      flesch: 27
     summary: key: cord-331328-qom8vl94 authors: Gianfrancesco, Milena A; Hyrich, Kimme L; Gossec, Laure; Strangfeld, Anja; Carmona, Loreto; Mateus, Elsa F; Sufka, Paul; Grainger, Rebecca; Wallace, Zachary; Bhana, Suleman; Sirotich, Emily; Liew, Jean; Hausmann, Jonathan S; Costello, Wendy; Robinson, Philip; Machado, Pedro M; Yazdany, Jinoos title: Rheumatic disease and COVID-19: initial data from the COVID-19 Global Rheumatology Alliance provider registries date: 2020-04-16 journal: Lancet Rheumatol DOI: 10.1016/s2665-9913(20)30095-3 sha: doc_id: 331328 cord_uid: qom8vl94 nan Individuals with inflammatory rheumatic disease require special consideration with regard to coronavirus disease 2019 , caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). 1-4 However, some disease-modifying drugs commonly used to treat rheumatic diseases, such as hydroxychloro quine, are being investigated as potential therapies for COVID-19.
    keywords: covid-19; data; disease; global; individuals; rheumatology
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        item: #5910 of 7819
          id: cord-331336-4kf2jn8c
      author: Aravindakshan, A.
       title: Restarting after COVID-19: A Data-driven Evaluation of Opening Scenarios
        date: 2020-05-30
       words: 4004
      flesch: 51
     summary: Initial analysis of the impact of policy restrictions in China suggests that NPIs that significantly affected human mobility (e.g., household quarantine) reduced the spread of the disease (7, 10) , even more than restrictions that limited national and international travel (11) . The results confirm that policy restrictions are not all equal in their ability to affect disease spread.
    keywords: covid-19; disease; license; mobility; preprint; restrictions; spread
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        item: #5911 of 7819
          id: cord-331375-tbuijeje
      author: Villalobos, Carlos
       title: SARS-CoV-2 Infections in the World: An Estimation of the Infected Population and a Measure of How Higher Detection Rates Save Lives
        date: 2020-09-25
       words: 7208
      flesch: 42
     summary: Moreover, we showed evidence that moving from relatively low to high cumulative detection rates (and thus saving lives) is unlikely and difficult. Thirdly, in this paper, we test the hypothesis that higher detection rates can save lives while providing a measure of this impact (having in mind that is preferable to be vaguely right than precisely wrong).
    keywords: cov-2; deaths; detection; detection rates; individuals; infections; number; pandemic; rates; sars
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        item: #5912 of 7819
          id: cord-331378-3nqn48z7
      author: Wand, Anne Pamela Frances
       title: COVID-19: the implications for suicide in older adults
        date: 2020-04-30
       words: 3949
      flesch: 39
     summary: Perspectives from SARS to Ebola The psychological impact of quarantine and how to reduce it: rapid review of the evidence Exploring the use of telephone helpline pertaining to older adult suicide prevention: Older people have been specifically advised to stay home given their vulnerability to COVID-19 and to reduce the burden on health services by limiting the spread of the illness.
    keywords: covid-19; et al; health; pandemic; people; services; suicide
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        item: #5913 of 7819
          id: cord-331394-zie0tmvt
      author: Singh, Surendra
       title: Data on social and health vulnerability in rural India: A Case of Covid-19
        date: 2020-07-14
       words: 1188
      flesch: 51
     summary: Also, household have knowledge of social distancing (i.e., 88.23%), while households marginally has awareness about testing procedure of Covid-19. Additionally, about 80.23% of household went of self-quarantine, while about 34.23% of households have consulted to doctors over Covid-19 (Fig. 2) .
    keywords: covid-19; data; health
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        item: #5914 of 7819
          id: cord-331405-1opm5onj
      author: Pessa Valente, Emanuelle
       title: COVID-19 among health workers in Brazil: The silent wave
        date: 2020-06-17
       words: 1050
      flesch: 49
     summary: ber of COVID-19 cases and related deaths among HW, in particular in selected states such as São Paulo and Maranhão, is rapidly increasing [11] . As many states are currently implementing massive rapid test programs, increased numbers of COVID-19 cases among HW are expected in coming weeks.
    keywords: cases; covid-19; data; states
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        item: #5915 of 7819
          id: cord-331427-lwpjj3b9
      author: Faulkner, J.
       title: Physical activity, mental health and well-being of adults during early COVID-19 containment strategies: A multi-country cross-sectional analysis
        date: 2020-07-16
       words: 4874
      flesch: 45
     summary: Although there were no differences in PA during early COVID-19 restrictions between these two countries, or indeed any of the countries surveyed, there were differences in exercise behaviour change between pre-and during COVID-19 restrictions. [7] Participants self-reported their pre-and during COVID-19 exercise behaviour based on one of the following statements: i) I currently do not exercise and do not intend to start in the next 6 months; ii) I currently do not exercise but I am thinking about starting in the next 6 months; iii) I currently exercise a little but not regularly; iv) I currently exercise regularly but have begun doing so in the last 6 months; or v) I currently exercise regularly and have done so for more than 6 months.
    keywords: behaviour; change; covid-19; exercise; health; preprint; restrictions
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        item: #5916 of 7819
          id: cord-331428-6pvr2vew
      author: Heffernan, Kevin S.
       title: Exercise as medicine for COVID-19: on PPAR with emerging pharmacotherapy
        date: 2020-08-17
       words: 1837
      flesch: 11
     summary: Expression of peroxisome proliferatoractivated receptor alpha (PPAR alpha) in primary cultures of human vascular endothelial cells Fatty acid carbon is essential for dNTP synthesis in endothelial cells A Protective Effect of PPARα in Endothelial Progenitor Cells Through Regulating Metabolism PPARalpha and GR differentially down-regulate the expression of nuclear factor-kappaB-responsive genes in vascular endothelial cells NAD(P)H oxidase/nitric oxide interactions in peroxisome proliferator activated receptor (PPAR)alpha-mediated cardiovascular effects Fenofibrate suppresses microvascular inflammation and apoptosis through adenosine monophosphate-activated protein kinase activation Fenofibrate activates AMPK and increases eNOS phosphorylation in HUVEC The peroxisome proliferator-activated receptor α agonist fenofibrate decreases airway reactivity to methacholine and increases endothelial nitric oxide synthase phosphorylation in mouse lung PPARalpha activators upregulate eNOS activity and inhibit cytokine-induced NF-kappaB activation through AMP-activated protein kinase activation Peroxisome Proliferator-Activated Receptor α Agonists Increase Nitric Oxide Synthase Expression in Vascular Endothelial Cells PPAR-α Agonist Fenofibrate Upregulates Tetrahydrobiopterin Level through Increasing the Expression of Guanosine 5'-Triphosphate Cyclohydrolase-I in Human Umbilical Vein Endothelial Cells Effect of fenofibrate on serum nitric oxide levels in patients with hypertriglyceridemia, Advances in clinical and experimental medicine : official organ Fenofibrate improves vascular endothelial function by reducing oxidative stress while increasing endothelial nitric oxide synthase in healthy normolipidemic older adults Fibrate therapy and flow-mediated dilation: A systematic review and meta-analysis of randomized placebocontrolled trials Strong Relationship Between Vascular Function in the Coronary and Brachial Arteries Peripheral Vascular Endothelial Function And The Pulmonary Blood Pressure Response To Exercise In Pulmonary Hypertension Coronary flow velocity reserve is improved by PPAR-α agonist fenofibrate in patients with hypertriglyceridemia Fenofibrate improves cerebral blood flow after middle cerebral artery occlusion in mice PPARα activation improves endothelial dysfunction and reduces fibrosis and portal pressure in cirrhotic rats Effects of the PPAR-α agonist fenofibrate on acute and short-term consequences of brain ischemia Effect of endurance training on lipid metabolism in women: a potential role for PPARalpha in the metabolic response to training Transcriptional adaptations of lipid metabolism in tibialis anterior muscle of endurance-trained athletes Vascular effects of exercise: endothelial adaptations beyond active muscle beds Exercise modalities and endothelial function: a systematic review and dose-response meta-analysis of randomized controlled trials, Sports medicine The antiinflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease Physical exercise as a tool to help the immune system against COVID-19: an integrative review of the current literature Prevention of age-related endothelial dysfunction by habitual aerobic exercise in healthy humans: possible role of nuclear factor κB Adolph Distinguished Lecture: The remarkable anti-aging effects of aerobic exercise on systemic arteries Effects of exercise training on endothelial progenitor cells in cardiovascular disease: a systematic review PPARδ Is Required for Exercise to Attenuate Endoplasmic Reticulum Stress and Endothelial Dysfunction in Diabetic Mice Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. This paper will explore the hypothesis that exercise may be a useful adjuvant in a setting of COVID-19 management/rehabilitation due to its effects on PPARα and vascular endothelial function.
    keywords: covid-19; effects; endothelial; exercise; lung; receptor
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        item: #5917 of 7819
          id: cord-331433-uwbgv0r3
      author: Tringale, Rolando
       title: COVID-19 innovations in medication for addiction treatment at a Skid Row syringe exchange
        date: 2020-10-21
       words: 1579
      flesch: 23
     summary: Pre-pandemic, clinicians primarily delivered MAT services at HHCLA (Tringale, Subica, & Danielian, et al., 2020) face-to-face to enrolled patients of syringe exchanges using a direct dispensing model that required patients to receive, and often consume, MAT medications (i.e., buprenorphine) on-site in front of staff to (1) bolster engagement among first-time patients hesitant to stop using opioids; (2) prevent diversion; and (3) avoid medication gaps, which can lead to relapse, overdose, and death. One practical limitation of the -coordinated pharmacy‖ model is that we had to ensure that MAT patients picked up their prescriptions without anyone accompanying them, as pre-COVID-19 HHCLA staff accompanied them.
    keywords: covid-19; hhcla; mat; patients; syringe
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        item: #5918 of 7819
          id: cord-331434-2x9m37cw
      author: Kumar Jain, Vijay
       title: Fracture management during COVID-19 pandemic: A systematic review and meta-analysis
        date: 2020-06-30
       words: 4999
      flesch: 50
     summary: BMJ evidence-based medicine Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan Is operative delay associated with increased mortality of hip fracture patients? Notingham hip fracture score(NFHS) and clinical frailty score(CFS) added together to make a SHIFT score may be used to select hip fracture cases for surgery in the COVID era, with patient to be considered for non-operative care if the score is more than 12, due to high risk og mortality in this group(53%).The mortality risk was 34% with score 9-12 and just 2% with score less than 9. ASJ Rabie H et al
    keywords: care; cases; covid; covid-19; emergency; fractures; mortality; pandemic; patients; risk; studies; surgery
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        item: #5919 of 7819
          id: cord-331442-ztzug9j4
      author: None
       title: Introducing special cutaneous “sign” tribute to healthcare workers managing new coronavirus disease (Covid −19)()()
        date: 2020-04-19
       words: 332
      flesch: 48
     summary: 4 Covid-19 pandemic and the skin -What should dermatologists know? Letter from the Editor: Occupational skin disease among healthcare workers during the Coronavirus (COVID-19) epidemic Nursing strategies for skin injuries caused by facial medical grade protective equipment Medical Device Related pressure ulcers in Hospitalized patients 1,2 Protective gear is well sealed against the skin, and high-intensity work of medical staff will generate a lot of sweat.
    keywords: skin
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        item: #5920 of 7819
          id: cord-331449-0sow1im8
      author: Saha, Shivangi
       title: Managing Burns During COVID-19 Outbreak
        date: 2020-05-30
       words: 2420
      flesch: 50
     summary: COVID-19: protecting health-care workers Management of elderly burn patients Training | Personal Protective Equipment (PPE) | Public Health Planners | Ebola (Ebola Virus Disease) | CDC COVID-19: the case for health-care worker screening to prevent hospital transmission The incubation period of coronavirus disease 2019 (covid-19) from publicly reported confirmed cases: estimation and application Personal protective equipment during the COVID-19 pandemic-a narrative review Recommendations for the regulation of medical practices of burn treatment during the outbreak of the coronavirus disease 2019 Management strategy of novel coronavirus pneumonia in burn and wound care ward CT imaging features of 2019 novel coronavirus (2019-nCoV) Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR COVID-19: In this review, we aim to highlight the key considerations for burn care teams while dealing with burn patients during the COVID-19 pandemic.
    keywords: burn; care; coronavirus; covid-19; disease; patients; procedures
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        item: #5921 of 7819
          id: cord-331472-kd4uxcve
      author: Shahid, Zainab
       title: COVID‐19 and Older Adults: What We Know
        date: 2020-04-20
       words: 2321
      flesch: 44
     summary: Report of the WHO-China Joint Mission on Coronavirus Disease Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Report sulle caratteristiche dei pazienti deceduti positivi a COVID-19 in Italia Il presente report è basato sui dati aggiornati al 17 Marzo 2020 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Hypertension prevalence and control among adults: United States Heart Disease, Myocardial Infarction, and Stroke-A Public Health Issue Chronic Obstructive Pulmonary Disease Among Adults-United States Identifying and interrupting superspreading eventsimplications for control of severe acute respiratory syndrome coronavirus 2 Air, surface environmental, and personal protective equipment contamination by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a symptomatic patient Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents Chloroquine is a potent inhibitor of SARS coronavirus infection and spread ? More than 80% of deaths among adult patients occurred in those older than age 65.
    keywords: adults; coronavirus; cov-2; covid-19; disease; patients; sars
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        item: #5922 of 7819
          id: cord-331477-2x9szmjc
      author: Warnakulasuriya, Saman
       title: Protecting dental manpower from COVID‐19 infection
        date: 2020-06-01
       words: 1877
      flesch: 46
     summary: Dental patients could have a strong urge to spit after a procedure. While the transmission of COVID 19 via human ex-haled droplets and direct contact is clear, the potential for aerosol transmission is a significant risk particularly for dental practices.
    keywords: bcg; covid-19; oral; patients; symptoms; vaccine
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        item: #5923 of 7819
          id: cord-331481-zeaqi1uc
      author: Al-Ani, Fatimah
       title: Thrombosis risk associated with COVID-19 infection. A scoping review
        date: 2020-05-27
       words: 4642
      flesch: 38
     summary: We conducted a scoping review using a single engine search for studies assessing thrombosis and coagulopathy in COVID-19 patients. In case reports of COVID-19 patients, PE was identified in patients with no VTE risk factors 28 .
    keywords: covid-19; disease; patients; risk; studies; study; survivors; thrombosis
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        item: #5924 of 7819
          id: cord-331486-jp4m6ibe
      author: Naccarato, Marcello
       title: Has COVID-19 played an unexpected “stroke” on the chain of survival?
        date: 2020-05-06
       words: 1448
      flesch: 51
     summary: To evaluate the effects of the COVID-19 pandemics on stroke management, this report described the emergency structured pathway adopted by an Italian University Hub Stroke Unit in the cross -border Italy-Slovenia area (which serves 373'803 people) (data from Istituto Nazionale di Statistica-ISTAT official report, 30th September 2017, see http://dati.istat.it/), and compared clinical features and outcomes of admitted patients between 9th March 2020 (start of Italy lockdown) and 9th April 2020 with stroke patients admitted during the same period in 2019. The COVID-19 pandemics required several changes in stroke management and it may have influenced some clinical or functional characteristics.
    keywords: covid-19; italy; patients; stroke
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        item: #5925 of 7819
          id: cord-331487-jh34klbg
      author: Sivapalan, Pradeesh
       title: Proactive Prophylaxis With Azithromycin and HydroxyChloroquine in Hospitalised Patients With COVID-19 (ProPAC-COVID): A structured summary of a study protocol for a randomised controlled trial
        date: 2020-06-10
       words: 6407
      flesch: 42
     summary: The length of hospitalisation is observed to be relatively long, 10-15 days (3) , which in itself is a problem as hospitals can quickly reach the maximum capacity for hospitalisation and the proportion of patients who become critically ill have, based on the observations reported so far, had a mortality rate of> 60% (4), and overall mortality for admitted patients in China with COVID-19 infection is apparently unusually high for viral respiratory tract infections with an estimate of 25% (2). Annual monitoring after 5 years of treatment is recommended, however in risk patients initially annual control, see also Chloroquine derivatives (inflammatory rheumatic diseases), side effects.
    keywords: azithromycin; consent; covid-19; data; days; group; hydroxychloroquine; information; intervention; medication; patients; project; study; treatment; trial
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        item: #5926 of 7819
          id: cord-331519-ye4dtna5
      author: Garibaldi, B. T.
       title: Patient trajectories and risk factors for severe outcomes among persons hospitalized for COVID-19 in the Maryland/DC region
        date: 2020-05-26
       words: 4523
      flesch: 51
     summary: Conclusions: A combination of demographic and clinical features on admission is strongly associated with progression to severe disease or death in a US cohort of COVID-19 patients. An elevated D-dimer is associated with increased risk of death in COVID-19 patients independent of documented thromboembolic disease, but could also indicate an increased risk of thrombosis.
    keywords: author; covid-19; death; disease; funder; medrxiv; patients; peer; preprint; review
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        item: #5927 of 7819
          id: cord-331520-o9e4qqn4
      author: Kistler, Christine E.
       title: The Winter Respiratory Viral Season During the COVID-19 Pandemic
        date: 2020-10-26
       words: 2728
      flesch: 28
     summary: Managing Investigations During an Outbreak CMS-3401-IFC, Updating Requirements for Reporting of SARS-CoV-2 Test Results by (CLIA) Additional Policy and Regulatory Revisions in Response to the COVID-19 Public Health Emergency Thinking fast and slow in pneumonia Computerized clinical decision support systems and antibiotic prescribing: a systematic review and meta-analysis Effectiveness and safety of electronically delivered prescribing feedback and decision support on antibiotic use for respiratory illness in primary care: REDUCE cluster randomised trial Evaluation of viruses associated with acute respiratory infections in long-term care facilities using a novel method: Wisconsin, 2016-2019 COVIDApp as an innovative strategy for the management and follow-up of COVID-19 cases in long-term care facilities in Catalonia: implementation study Prognostic value of lung ultrasonography in older nursing home residents affected by COVID-19 Combining procalcitonin and rapid multiplex respiratory virus testing for antibiotic stewardship in older adult patients with severe acute respiratory infection Efficacy of a test-retest strategy in residents and health care personnel of a nursing home facing a COVID-19 outbreak Bacterial and fungal co-infection in individuals with coronavirus: a rapid review to support COVID-19 antimicrobial prescribing Does adherence to the Loeb minimum criteria reduce antibiotic prescribing rates in nursing homes? Successfully reducing antibiotic prescribing in nursing homes Antibiotic use in the nursing home. Different Types of Flu Vaccines Use of 13-Valent Pneumococcal Conjugate Vaccine and 23-Valent Pneumococcal Polysaccharide Vaccine Among Adults Aged ≥65 Years: Updated Recommendations of the Advisory Committee on Immunization Practices Pneumococcal vaccination guidance for post-acute and long-term care settings: recommendations from AMDA's Infection Advisory Committee Recommendations for mandatory influenza vaccinations for health care personnel from AMDA's Infection Advisory Subcommittee Influenza vaccination coverage among health care personnel -United States, 2017-18 influenza season Changes in influenza vaccination requirements for health care personnel in us hospitals Barriers to timely care of acute infections in nursing homes: a preliminary qualitative study Nursing home-associated pneumonia, part I: diagnosis Defining characteristics and risk indicators for diagnosing nursing home-acquired pneumonia and aspiration pneumonia in nursing home residents, using the electronically-modified Delphi Method Community-acquired pneumonia requiring hospitalization among U.S. adults Predictors of mortality for nursing home-acquired pneumonia: a systematic review Viral respiratory infections in a nursing home: a sixmonth prospective study Unprecedented solutions for extraordinary times: Helping long-term care settings deal with the COVID-19 pandemic Role of body temperature in diagnosing bacterial infection in nursing home residents Temperature in nursing home residents systematically tested for SARS-CoV-2 Clinical practice guideline for the evaluation of fever and infection in older adult residents of long-term care facilities: 2008 update by the Infectious Diseases Society of America Does universal testing for COVID-19 work for everyone? Centers for Disease Control and Prevention.
    keywords: care; covid-19; nursing; residents; respiratory; term; winter
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        item: #5928 of 7819
          id: cord-331533-0toegbv8
      author: Leiker, Brenna
       title: COVID – 19 CASE STUDY IN EMERGENCY MEDICINE PREPAREDNESS AND RESPONSE; FROM PERSONAL PROTECTIVE EQUIPMENT TO DELIVERGY OF CARE
        date: 2020-07-27
       words: 12834
      flesch: 46
     summary: Staff was re-allocated to essential areas such as the ED, ICU, home health, and nursing homes to help test and care for COVID patients. The physical space of the emergency room was re-evaluated to best triage and isolate COVID patients.
    keywords: areas; care; cases; coronavirus; covid; covid-19; emergency; exposure; hospital; intubation; march; mask; northshore; oxygen; pandemic; patients; ppe; protocols; room; staff; testing; time; use
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        item: #5929 of 7819
          id: cord-331541-u0xm9a89
      author: Lankes, Heather A
       title: Biospecimen Collection During the COVID-19 Pandemic: Considerations for Biobanking
        date: 2020-09-25
       words: 3589
      flesch: 34
     summary: Thus, similar to the categorization used in Hong Kong for SARS biospecimens, 42 a third category should be considered, ie, all biospecimens collected internationally during the pandemic window of October 1, 2019, through a yet to be determined date ❚Table 1❚. China confirms SARS infection in another previously reported case; summary of cases to date-update 5 Severe acute respiratory syndrome (SARS) in Singapore-update 2 World Health Organization.
    keywords: biosafety; biospecimens; cov-2; covid-19; handling; laboratory; pandemic; sars
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        item: #5930 of 7819
          id: cord-331547-uqmjhhna
      author: Bonalumi, Giorgia
       title: A call to action becomes practice: cardiac and vascular surgery during the COVID-19 pandemic based on the Lombardy emergency guidelines
        date: 2020-06-25
       words: 4239
      flesch: 47
     summary: A cross-sectional study COVID-19 outbreak In Northern Italy viewpoint of the Milan area surgical community The COVID-19 outbreak and its impact on hospitals in Italy: the model of cardiac surgery Ministero della salute, Italia, National Plan for Hospital Waiting List jsp?lingua=italiano&id=2824 Chinese society of anesthesiology expert consensus on anesthetic management of cardiac surgical patients with suspected or confirmed coronavirus disease 2019 Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 Critically ill COVID-19 infected patients exhibit increased clot waveform analysis parameters consistent with hypercoagulability Associations between immune-suppressive and stimulating drugs and novel COVID-19-a systematic review of current evidence COVID-19 and treatment with NSAIDs and corticosteroids: should we be limiting their use in the clinical setting? Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Renin-angiotensin system blockers and the COVID-19 pandemic: at present there is no evidence to abandon renin-angiotensin system blockers Conflict of interest: none declared. Further studies are needed to quantify the number of cardiovascular patients who died of SARS-CoV-2.
    keywords: area; covid-19; emergency; hospital; hub; patients; results; screening; spoke; system
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        item: #5931 of 7819
          id: cord-331601-3w4c40qr
      author: Ojong, Nathanael
       title: The COVID-19 Pandemic and the Pathology of the Economic and Political Architecture in Cameroon
        date: 2020-06-17
       words: 8031
      flesch: 51
     summary: The major difference between African countries and Western countries is that in most cases, the latter have the capacity to mobilise resources needed by health care systems at short notice, while the former often do not have that capacity. In the past, there has been large-scale drug thefts and small-scale pilfering, and the limited drugs that reached public health care institutions due to the reduction in public health expenditures were given to local authorities, family members, and friends before patients could benefit from them [75] .
    keywords: cameroon; care; countries; country; covid-19; disease; economy; government; health; health care; institutions; pandemic; people; public; spread; system
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        item: #5932 of 7819
          id: cord-331604-jf6ybip5
      author: Moratto, Daniele
       title: Flow Cytometry Identifies Risk Factors and Dynamic Changes in Patients with COVID-19
        date: 2020-06-27
       words: 1908
      flesch: 35
     summary: Clinical characteristics of coronavirus disease 2019 in China Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical course and risk factors for mortality of adult inpatients with COVID-19 in China: a retrospective cohort study Impaired type I interferon activity and exacerbated inflammatory responses in severe Covid-19 patients Clinical presentation and initial management critically ill patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Brescia, Italy Antibody responses to SARS-CoV-2 in patients with COVID-19 Viral kinetics and antibody responses in patients with COVID-19 Complex immune dysregulation in COVID-19 patients with severe respiratory failure Increased HLA-DR expression on peripheral blood monocytes in subsets of subjects with primary HIV infection is associated with elevated CD4 T-cell apoptosis and CD4 T-cell depletion Altered monocyte phenotype in HIV-1 infection tends to normalize with integrase-inhibitor-based antiretroviral therapy Inhibition of Bruton tyrosine kinase in patients with severe COVID-10 Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Furthermore, patients with severe disease had a significantly reduced number of TCRγδ + T cells, and an abnormal distribution of CD8 + T cell subsets, with lower proportion of naïve cells and increased percentage of effector CD45RA
    keywords: admission; clinical; covid-19; disease; patients; phenotype
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        item: #5933 of 7819
          id: cord-331666-iwkuwnun
      author: Schweitzer, Wolf
       title: Implications for forensic death investigations from first Swiss post-mortem CT in a case of non-hospital treatment with COVID-19
        date: 2020-06-30
       words: 3816
      flesch: 40
     summary: As relevant as that may appear to forensic investigations, this seems rather uninformative otherwise, and may definitely entail under-reporting of COVID-19 cases [58] when in fact, death with COVID-19 (as in: fall from great height, intoxication, road traffic accident, etc.) The extent of pulmonary affection in this case, both radiologically (see Fig. 2 and 3 ) and at autopsy, seems extensive in context of SARS-CoV-2 cases reported so far [42] but lies in the range of fatal SARS cases [43] .
    keywords: acute; case; coronavirus; cov-2; covid-19; death; findings; patients; pmct; post; sars
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        item: #5934 of 7819
          id: cord-331688-88veckbv
      author: Pavlakis, Steven
       title: Fear and Understanding in the Time of COVID-19
        date: 2020-06-26
       words: 1129
      flesch: 48
     summary: An anesthesiologist friend tells us that, at State University of New York, Stony Brook, they are intubating about 18 patients per day for COVID-19 pulmonary disease. Stroke investigations in adult patients are planned and pediatric neurology should be investigating stroke associations as well.
    keywords: covid-19; disease; patients
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        item: #5935 of 7819
          id: cord-331762-b0yufidn
      author: Rudski, Lawrence
       title: Multimodality Imaging in Evaluation of Cardiovascular complications in Patients with COVID-19
        date: 2020-07-22
       words: 5051
      flesch: 24
     summary: Imaging findings typically associated with chronic cardiac conditions such as LVH and LV dilatation, have been well described in acute cardiac presentations of COVID-19 patients and have demonstrated significant reversibility and may not be reliable markers to judge chronicity of cardiac dysfunction (31) . Below are the key summary points from this expert panel guidance regarding the use of multimodality imaging in COVID-19 patients: • TTE is usually the initial cardiovascular imaging modality used to guide management.
    keywords: acute; cardiac; coronary; covid-19; disease; heart; imaging; injury; management; patients
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        item: #5936 of 7819
          id: cord-331765-pk0fr0a1
      author: Salaffi, Fausto
       title: The role of a chest computed tomography severity score in coronavirus disease 2019 pneumonia
        date: 2020-10-16
       words: 3577
      flesch: 39
     summary: RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak A novel coronavirus from patients with pneumonia in China Eurosurveillance Editorial TNote from the editors: World Health Organization declares novel coronavirus (2019-nCoV) sixth public health emergency of international concern Covid-19: WHO declares pandemic because of alarming levels of spread, severity, and inaction Early transmission Dynamics in Wuhan, China, of novel coronavirus-infected pneumonia Coronavirus covid-19 has killed more people than SARS and MERS combined, despite lower case fatality rate Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Critical care utilization for the COVID-19 outbreak in Lombardy, Italy: early experience and forecast during an emergency response COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options Epidemiological, clinical, and virological characteristics of 465 hospitalized cases of coronavirus disease 2019 (COVID-19) from Zhejiang province in China Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study The clinical and chest CT features associated with severe and critical COVID-19 pneumonia CT chest findings in coronavirus disease-19 (COVID-19) Sensitivity of chest CT for COVID-19: comparison to RT-PCR Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection Temporal changes of CT findings in 90 patients with COVID-19 pneumonia: a longitudinal study Chest radiographic and CT findings of the 2019 novel coronavirus disease (COVID-19): analysis of nine patients treated in Korea An update on current therapeutic drugs treating COVID-19 Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected: interim guidance CI = confidence interval, +LR = positive likelihood ratio, -LR = negative likelihood ratio, * =optimal cut-off value Medicine (2020) 99:42 Medicine default-source/coronaviruse/clinical-management-of-novel-covpdf? The aim of this study was to investigate chest CT findings in COVID-19 patients in order to determine the optimal cut-off value of a CT severity score that can be considered a potential prognostic indicator of a severe/critical outcome.
    keywords: covid-19; disease; lung; patients; pneumonia; score; severity
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        item: #5937 of 7819
          id: cord-331785-ljsd8qld
      author: None
       title: A Systematic Framework to Rapidly Obtain Data on Patients with Cancer and COVID-19:CCC19 Governance, Protocol, and Quality Assurance
        date: 2020-10-29
       words: 2719
      flesch: 32
     summary: In addition to the steering committee, operational subcommittees include publications (to establish authorship guidelines for projects utilizing CCC19 data and/or resources), funding (to identify sources of funding for the consortium, disseminate this information to consortium members, and assist in the writing and critical revision of grants), epidemiology and biostatistics (to establish guidelines and provide support to investigators in designing and executing studies with the highest rigor, reproducibility, and impact), informatics (to develop and maintain the survey instrument[s] and oversee standardization of the data model, integration of data directly from EHRs, and visualization of data), and patient advocacy (to engage with cancer patient communities and advocacy networks and to coordinate with parties reaching out to CCC19). An analysis of data quality at the time of the fourth data lock (July 31, 2020) indicated that the overall quality of reports was acceptable but in need of improvement, with 78% of cases meeting the predetermined threshold ( Figure 2B ).
    keywords: cancer; ccc19; covid-19; data; patients
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        item: #5938 of 7819
          id: cord-331790-0w0pjjg1
      author: Abu Jawdeh, Bassam G.
       title: COVID-19 in Kidney Transplantation: Outcomes, Immunosuppression Management and Operational Challenges
        date: 2020-07-17
       words: 3060
      flesch: 41
     summary: Multiple case series of kidney transplant recipients with COVID-19 have shown increased mortality compared to non-transplant patients. These comorbidities are prevalent in patients with kidney disease, hence the significant burden of COVID-19 on kidney transplant programs.
    keywords: covid-19; disease; immunosuppression; kidney; ktr; patients; sars; transplant
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        item: #5939 of 7819
          id: cord-331797-05kcygis
      author: Restauri, Nicole
       title: Burnout and PTSD in the COVID-19 Pandemic: Intersection, Impact and Interventions
        date: 2020-05-27
       words: 2833
      flesch: 26
     summary: Individual physicians and hospital administration should take proactive steps to minimize the compounding effects of high baseline physician burnout with the acute stressors of the COVID-19 pandemic. This pandemic has exacerbated stressors in a healthcare system in which physician burnout, a response to workplace stress, is already epidemic (2) .
    keywords: burnout; covid-19; pandemic; physician; ptsd; stress; work
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        item: #5940 of 7819
          id: cord-331815-518wljiy
      author: amram, o.
       title: Data-Driven Development of a Small-Area COVID-19 Vulnerability Index for the United States
        date: 2020-08-18
       words: 3319
      flesch: 42
     summary: Research and surveillance data indicate that COVID-19 infection risk is not evenly distributed, but rather increased in certain sociodemographic populations, particularly those who are socially and economically marginalized. 17.20176248 doi: medRxiv preprint In this study, we assessed socio-demographic and economic predictors of COVID-19 infection risk at the U.S. ZIP-code level, based on sampling of publicly-available data.
    keywords: covid-19; license; medrxiv; population; preprint; risk
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        item: #5941 of 7819
          id: cord-331830-vr2eqsbq
      author: Sawalha, Khalid
       title: Systematic Review of COVID-19 Related Myocarditis: Insights on Management and Outcome
        date: 2020-08-18
       words: 2830
      flesch: 45
     summary: First, our study is limited to cases reports which imparts potential selection bias since reported cases are usually unique cases in presentation and management. However, guidelines for the diagnosis of COVID-19 myocarditis have not been established.
    keywords: cases; covid-19; management; myocarditis; outcomes; patients
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        item: #5942 of 7819
          id: cord-331834-ge864rbr
      author: Cellina, Michaela
       title: Chest computed tomography findings of COVID-19 pneumonia: pictorial essay with literature review
        date: 2020-06-25
       words: 2622
      flesch: 43
     summary: For each article, the following data were collected, when available: patient demographics, lobar involvement, distribution pattern, chest CT findings, evolution of chest CT findings. Chest X-Rays showed little diagnostic value in early stages [6] , whereas chest Computed Tomography (CT) showed a high sensitivity for the diagnosis of COVID-19, particularly important in COVID-19 patients with falsenegative RT-PCR result, assuming a role for the CT as a primary tool for COVID-19 diagnosis in the epidemic areas [5, [7] [8] [9] .
    keywords: chest; coronavirus; covid-19; disease; patients; pneumonia
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        item: #5943 of 7819
          id: cord-331858-oz4mvyw8
      author: Kifer, D.
       title: Effects of environmental factors on severity and mortality of COVID-19
        date: 2020-07-14
       words: 5520
      flesch: 41
     summary: In Zhejiang hospitals, ASST Papa Giovanni XXIII° Hospital in Bergamo, Hospital del Mar in Barcelona and Helsinki University Hospital local ethics committees approved this retrospective study of COVID-19 patient data. Exchanging hospital admission date with local temperature (Figure 2 ) showed that temperature strongly correlated with decrease in COVID-19 mortality.
    keywords: admission; analysis; covid-19; date; hospitals; license; medrxiv; patients; preprint; severity; temperature
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        item: #5944 of 7819
          id: cord-331869-dm8ri6xf
      author: Lau, Louis HS.
       title: Collateral Effect of COVID-19 Pandemic on Hospitalizations and Clinical Outcomes in Gastrointestinal and Liver Diseases – A Territory-wide Observational Study in Hong Kong
        date: 2020-07-25
       words: 2070
      flesch: 35
     summary: Hospital admissions through the emergency department, or those with a length of stay more than one day were included. [6] The primary endpoint was the total number of hospital admissions, related to the principal or top five diagnoses of major diseases.
    keywords: covid-19; diseases; emergency; hospital; january; patients
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        item: #5945 of 7819
          id: cord-331879-w7008uyy
      author: Iversen, Jenny
       title: COVID‐19, HIV and key populations: cross‐cutting issues and the need for population‐specific responses
        date: 2020-10-01
       words: 3691
      flesch: 31
     summary: The negative consequences of these measures on general population health and well-being, such as mental health issues arising from isolation, loss of income and residential instability, will be exacerbated in vulnerable key populations who lack the resources to physically distance or who do not have access to social safety nets or the option of working from home [6] . key: cord-331879-w7008uyy authors: Iversen, Jenny; Sabin, Keith; Chang, Judy; Morgan Thomas, Ruth; Prestage, Garrett; Strathdee, Steffanie A; Maher, Lisa title: COVID‐19, HIV and key populations: cross‐cutting issues and the need for population‐specific responses date: 2020-10-01 journal: J Int AIDS Soc DOI: 10.1002/jia2.25632 sha: doc_id: 331879 cord_uid: w7008uyy INTRODUCTION:
    keywords: covid-19; health; hiv; pandemic; people; populations; sex; workers
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        item: #5946 of 7819
          id: cord-331888-lbtuvdv3
      author: de Souza, Dalton Garcia Borges
       title: Forecasting COVID-19 cases at the Amazon region: a comparison of classical and machine learning models
        date: 2020-10-09
       words: 2435
      flesch: 55
     summary: All those numbers caught the attention of many researchers, that presented models 11 to attend the concerns from the Brazilian government and population, such as when the 12 outbreak will peak, how long it will last, and how many will be infected or die [4, 5] . In each pair of models we can observe how the Holt-Winters perform in comparison 214 to an other model and considering the periods we classify as (1) exponential increasing, 215 (2) after sudden daily decreasing and (3) stability of daily new cases.
    keywords: arima; cases; covid-19; data; forecasting; models; regression
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        item: #5947 of 7819
          id: cord-331891-a6b1xanm
      author: Cozzi, Diletta
       title: Chest X-ray in new Coronavirus Disease 2019 (COVID-19) infection: findings and correlation with clinical outcome
        date: 2020-06-09
       words: 2919
      flesch: 43
     summary: Analysis of Variance (ANOVA) was performed to detect possible differences among RALE score estimated in the following groups: discharged patients, hospitalized patients into a medicine department, hospitalized patients into an ICU (respectively, group 1, 2 and 3 in the following). It is operationally much 2 Box and Whisker plot of RALE score estimated in each group defined by outcome: discharged patients (group 1), hospitalized patients into a medicine department (group 2), hospitalized patients into an intensive care unit (group 3).
    keywords: covid-19; cxr; group; patients; rale; score
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        item: #5948 of 7819
          id: cord-331910-s474ecvk
      author: Thota, Sai Manohar
       title: Natural products as home‐based prophylactic and symptom management agents in the setting of COVID‐19
        date: 2020-08-17
       words: 8699
      flesch: 22
     summary: Drug Design A trial of Lopinavir-Ritonavir in adults hospitalized with severe Covid-19 Vitamin C and immune function Features, evaluation and treatment coronavirus (COVID-19) Vitamin C in disease prevention and cure: An overview Fresh ginger (Zingiber officinale) has anti-viral activity against human respiratory syncytial virus in human respiratory tract cell lines Effects of curcumin on pulmonary fibrosis and functions of paraquatchallenged rats Apigenin protects against bleomycin-induced lung fibrosis in rats Protective roles of Cordyceps on lung fibrosis in cellular and rat models β-Patchoulene from patchouli oil protects against LPSinduced acute lung injury via suppressing NF-κB and activating Nrf2 pathways Oxidative stress and pulmonary fibrosis Naja naja atra venom ameliorates pulmonary fibrosis by inhibiting inflammatory response and oxidative stress β-carboline alkaloids attenuate bleomycin induced pulmonary fibrosis in mice through inhibiting NF-kb/p65 phosphorylation and epithelial-mesenchymal transition Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 (COVID-19) in Wuhan, China: A retrospective study Does Carica papaya leaf-extract increase the platelet count? Neem (Azadirachta indica) has potential therapeutic benefits against pulmonary fibrosis pulmonary inflammation, acute lung injury, and alveolar damage.
    keywords: acute; antioxidant; bleomycin; cells; coronavirus; covid-19; effects; et al; fibrosis; infection; injury; levels; lung; mice; patients; rats; sars; study; symptoms; syndrome; tgf
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        item: #5949 of 7819
          id: cord-331911-arif1ejj
      author: Barik, Sitanshu
       title: Insight into the changing patterns in clinical and academic activities of the orthopedic residents during COVID-19 pandemic: a cross-sectional survey
        date: 2020-09-14
       words: 2880
      flesch: 43
     summary: Like other specialties, orthopedic residents have been frontline soldiers in this battle against coronavirus pandemic since the beginning [4, 5] . Teams of orthopedic residents have been quarantined routinely or after being exposed to some COVID-19-positive patients.
    keywords: covid-19; orthopedic; pandemic; questions; residents; study
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        item: #5950 of 7819
          id: cord-331947-s97h7sxj
      author: Deng, H.-J.
       title: Cytokine biomarkers of COVID-19
        date: 2020-06-03
       words: 3957
      flesch: 48
     summary: Indeed, cytokine fluctuation was clearly observed in a previous study, which showed that IL-6, IP-10, MCP-1 and IL-15 levels fluctuated significantly over several days in subjects experimentally infected with influenza A virus [16] . (2) A similar fluctuation pattern for different cytokines indicates that these cytokines are partially redundant, at least statistically, in classifying different populations.
    keywords: covid-19; cytokines; license; medrxiv; patients; preprint; version
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        item: #5951 of 7819
          id: cord-331978-y4uo7o8g
      author: Maxwell, Daniel N
       title: “The Art of War” in the Era of Coronavirus Disease 2019 (COVID-19)
        date: 2020-03-04
       words: 1522
      flesch: 49
     summary: Their explicit protocols provide a framework for other healthcare and public health systems to weigh along with cost-effectiveness and scalability. As cases of COVID-19 explode internationally, a strategic shift is required away from primarily containment, keeping the virus out there, to home-based mitigation and public health responses.
    keywords: covid-19; hcw; health; ppe; public
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        item: #5952 of 7819
          id: cord-331995-7113c613
      author: Niles, P. Mimi
       title: Reflecting on Equity in Perinatal Care During a Pandemic
        date: 2020-07-28
       words: 1893
      flesch: 36
     summary: key: cord-331995-7113c613 authors: Niles, P. Mimi; Asiodu, Ifeyinwa V.; Crear-Perry, Joia; Julian, Zoë; Lyndon, Audrey; McLemore, Monica R.; Planey, Arianna M.; Scott, Karen A.; Vedam, Saraswathi title: Reflecting on Equity in Perinatal Care During a Pandemic date: 2020-07-28 journal: Health Equity DOI: 10.1089/heq.2020.0022 sha: doc_id: 331995 cord_uid: 7113c613 Growing discourse around maternity care during the pandemic offers an opportunity to reflect on how this crisis has amplified inequities in health care. Growing discourse around maternity care during the pandemic amplifies long-standing disparities and inequities in health care.
    keywords: care; covid-19; health; pandemic; providers
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        item: #5953 of 7819
          id: cord-332051-yw5zlucc
      author: Aghababaei, Soodabeh
       title: Perceived risk and protective behaviors regarding COVID-19 among Iranian pregnant women
        date: 2020-09-18
       words: 3817
      flesch: 42
     summary: key: cord-332051-yw5zlucc authors: Aghababaei, Soodabeh; Bashirian, Saeed; Soltanian, Alireza; Refaei, Mansoureh; Omidi, Tahereh; Ghelichkhani, Samereh; Soltani, Farzaneh title: Perceived risk and protective behaviors regarding COVID-19 among Iranian pregnant women date: 2020-09-18 journal: Middle East Fertil Soc J DOI: 10.1186/s43043-020-00038-z sha: doc_id: 332051 cord_uid: yw5zlucc BACKGROUND: Despite the vulnerability of pregnant women, few studies have been conducted on their perceived risk and protective behaviors during the COVID-19 pandemic. The present cross-sectional study aims to investigate the perceived risk and protective behaviors regarding COVID-19 among pregnant women, in Hamadan, Iran.
    keywords: behaviors; covid-19; knowledge; level; perception; risk; study; women
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        item: #5954 of 7819
          id: cord-332066-8mdg6172
      author: Thway, A. M.
       title: Epidemiological characteristics of SARS-COV-2 in Myanmar
        date: 2020-08-04
       words: 2899
      flesch: 49
     summary: The data series of COVID-19 cases were extracted from the daily official reports of the Ministry of Health and Sports (MOHS), Myanmar and Centers for Disease Control and Prevention (CDC), Myanmar. The data series of COVID-19 cases were extracted from the daily official reports .
    keywords: cases; covid-19; license; medrxiv; myanmar; preprint
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        item: #5955 of 7819
          id: cord-332071-bqvn3ceq
      author: Lee, Jeong Seok
       title: Immunophenotyping of COVID-19 and influenza highlights the role of type I interferons in development of severe COVID-19
        date: 2020-07-10
       words: 7122
      flesch: 46
     summary: Based on the distribution of UMI counts, the cluster 'Uncategorized 1' was featured by relatively high UMIs per cell compared to other clusters and presence of higher expression of multiple cell type marker genes. These results indicate that, in COVID-19, peripheral blood immune cells may be influenced by common inflammatory mediators regardless of cell type.
    keywords: analysis; cell; cluster; covid-19; disease; fig; genes; ifn; influenza; monocytes; patients; response; tnf; type
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        item: #5956 of 7819
          id: cord-332074-s824m91f
      author: Caillet, Anaëlle
       title: Psychological Impact of COVID-19 on ICU Caregivers
        date: 2020-09-29
       words: 2456
      flesch: 56
     summary: -The COVID-19 impact study was carried out exclusively in Lyon in the same hospital. Moreover, the daily lives of ICU caregivers have been rapidly disrupted.
    keywords: anxiety; caregivers; covid-19; icu; risk; study
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        item: #5957 of 7819
          id: cord-332078-vl309ss7
      author: Cipollaro, Lucio
       title: Musculoskeletal symptoms in SARS-CoV-2 (COVID-19) patients
        date: 2020-05-18
       words: 1422
      flesch: -17
     summary: Allergy Published Online First: 2 Clinical features and treatment of COVID-19 patients in northeast Chongqing Coronavirus disease 2019 in elderly patients: characteristics and prognostic factors based on 4-week follow-up Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan, China Clinical features and dynamics of viral load in imported and non-imported patients with COVID-19 Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Delivery of infection from asymptomatic carriers of COVID-19 in a familial cluster Risk factors associated with acute respiratory distress syndrome and death in patients with Coronavirus Disease Procalcitonin in patients with severe coronavirus disease 2019 (COVID-19): a meta-analysis Clinical features of 85 fatal cases of COVID-19 from Wuhan: a retrospective observational study Clinical features of 69 cases with Coronavirus Disease Clinical characteristics of Coronavirus Disease 2019 in China Clinical characteristics of pregnant women with Covid-19 in Wuhan, China Clinical characteristics of non-critically ill patients with novel coronavirus infection (COVID-19) in a Fangcang Hospital Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection Epidemiological characteristics and clinical features of 32 critical and 67 noncritical cases of COVID-19 in Chengdu Epidemiological and initial clinical characteristics of patients with family aggregation of COVID-19 Clinical characteristics and outcomes of hospitalised patients with COVID-19 treated in Hubei (epicenter) and outside Hubei (non-epicenter): a nationwide analysis of China High-resolution chest CT features and clinical characteristics of patients infected with COVID-19 in Jiangsu, China Clinical characteristics of 25 death cases with COVID-19: a retrospective review of medical records in a single medical center Clinical characteristics of 54 medical staff with COVID-19: a retrospective study in a single center in Wuhan Multicenter analysis of clinical characteristics and outcome of COVID-19 patients with liver injury Rapid asymptomatic transmission of COVID-19 during the incubation period demonstrating strong infectivity in a cluster of youngsters aged 16-23 years outside Wuhan and characteristics of young patients with COVID-19: a prospective contact-tracing study Characteristics of COVID-19 infection in Beijing Clinical characteristics of Covid-19 in New York City Analysis of epidemiological and clinical features in older patients with Corona Virus Disease 2019 (COVID-19) out of Wuhan Clinical and CT features in pediatric patients with COVID-19 infection: different points from adults Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) Pneumonia: A systematic review of COVID-19 epidemiology based on current evidence Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: a systematic review and meta-analysis Clinical value of immune-inflammatory parameters to assess the severity of coronavirus disease 2019 Symptom pathogenesis during acute influenza: interleukin-6 and other cytokine responses Rheumatologists' perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures Clinical characteristics of older patients: the experience of a geriatric short-stay unit dedicated to patients with COVID-19 in France Clinical characteristics of laboratory confirmed positive cases of SARS-CoV-2 infection in Wuhan, China: A retrospective single center analysis Clinical features and short-term outcomes of 102 patients with Corona Virus Disease Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms Clinical characteristics of 161 cases of corona virus disease 2019 (COVID-19) in Changsha Clinical characteristics of 80 hospitalized frontline medical workers infected with COVID-19 in Wuhan Clinical characteristics and outcomes of older patients with coronavirus disease 2019 (COVID-19) in Wuhan, China (2019): a single-centered, retrospective study Clinical and autoimmune characteristics of severe and critical cases with COVID-19 Evaluation of SARS-CoV-2 RNA shedding in clinical specimens and clinical characteristics of 10 patients with COVID-19 in Macau Clinical features of patients infected with 2019 novel coronavirus in Wuhan Epidemiological, clinical characteristics of cases of SARS-CoV-2 infection with abnormal imaging findings Clinical progression of patients with COVID-19 in Shanghai COVID-19 with different severity: a multi-center study of clinical features Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study COVID-19 in a designated infectious diseases hospital outside Hubei Province, China.
    keywords: characteristics; clinical; covid-19; patients
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        item: #5958 of 7819
          id: cord-332081-j13krdft
      author: Maldonado, María
       title: Incidencia y resultados de la COVID-19 en una unidad de diálisis domiciliaria en Madrid (España) durante el pico de la pandemia
        date: 2020-11-05
       words: 1891
      flesch: 45
     summary: Hay pocos datos sobre incidencia y evolución de la COVID-19 en los pacientes en diálisis. Además, ambos se contagiaron por transmisión nosocomial, lo que demuestra que probablemente presentaban un peor estado de salud que el resto de los pacientes afectados.
    keywords: centro; con; covid-19; del; diálisis; los; pacientes; patients; que
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        item: #5959 of 7819
          id: cord-332085-s58sd8e4
      author: Wissmath, B.
       title: Understanding the psychological impact of the COVID-19 pandemic and containment measures: an empirical model of stress.
        date: 2020-05-16
       words: 2060
      flesch: 50
     summary: Individual, economic, and societal worries are also expected to increase stress levels. A onesample Gauss test showed higher stress levels during the lockdown period, z=19.08, p <.001.
    keywords: individuals; measures; preprint; stress
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        item: #5960 of 7819
          id: cord-332087-xwturwju
      author: McGlynn, Fergal
       title: Argatroban for therapeutic anticoagulation for heparin resistance associated with Covid-19 infection
        date: 2020-08-24
       words: 1451
      flesch: 49
     summary: They recommend LMWH or UFH for therapeutic anticoagulation, for any indication, over direct oral anticoagulation (DOAC), and recommend considering measuring anti-Xa levels for anticoagulant monitoring. They also recommend measuring anti-Xa levels in patients with Covid-19 who are anticoagulated with heparin.
    keywords: anti; covid-19; heparin; patients
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        item: #5961 of 7819
          id: cord-332100-l3r7qxxm
      author: Wu, Chaomin
       title: Mental health status and related influencing factors of COVID‐19 survivors in Wuhan, China
        date: 2020-06-05
       words: 1196
      flesch: 51
     summary: COVID-19 survivors should not be overly worried for a rare event of recurrence, as we found a high proportion of survivors (46.8%) worried about recurrence. 4 However, few studies have reported the post-discharge follow-up status, especially the mental health status of COVID-19 survivors.
    keywords: covid-19; depression; survivors
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        item: #5962 of 7819
          id: cord-332108-6riu44fw
      author: Alanezi, Fahad
       title: Implications of Public Understanding of COVID-19 in Saudi Arabia for Fostering Effective Communication Through Awareness Framework
        date: 2020-09-18
       words: 4138
      flesch: 38
     summary: Working in healthcare organizations or having a qualification related to healthcare may increase the possibility that the participants were more aware of the infectious diseases/healthcare aspects compared to other participants. Objective: Focusing on these aspects, this manuscript reviews public awareness about COVID-19, myths surrounding it, its symptoms, treatment, transmission, importance of information sources, types of information to be considered in awareness campaigns, promotional channels, and their implications in Saudi Arabia.
    keywords: awareness; covid-19; information; participants; people; public; survey
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        item: #5963 of 7819
          id: cord-332109-ont0tqpn
      author: Wei, Yufeng
       title: Substance Use Disorder in the COVID-19 Pandemic: A Systematic Review of Vulnerabilities and Complications
        date: 2020-07-18
       words: 11749
      flesch: 35
     summary: The Janus face of immune enhancement Draft Landscape of COVID-19 Candidate Vaccines The COVID-19 vaccine development landscape An Evidence Based Perspective on mRNA-SARS-CoV-2 Vaccine Development An mRNA Vaccine against SARS-CoV-2-Preliminary Report Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: A dose-escalation, open-label, non-randomised Trials of anti-tumour necrosis factor therapy for COVID-19 are urgently needed Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): Anti-inflammatory strategies Breadth of concomitant immune responses prior to patient recovery: A case report of non-severe COVID-19 Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals Presence of SARS-CoV-2 reactive T cells in COVID-19 patients and healthy donors Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections The potential danger of suboptimal antibody responses in COVID-19 Antibody-Dependent Enhancement of Viral Infections Opioid use disorder and the COVID 19 pandemic: A call to sustain regulatory easements and further expand access to treatment Projecting the transmission dynamics of SARS-CoV-2 through the postpandemic period Comparing lung tissues from deceased patients of acute respiratory distress syndrome (ARDS) associated with influenza and COVID-19, the lungs from COVID-19 patients displayed distinctive vascular impairments of the pulmonary vessels.
    keywords: ace2; alcohol; axis; bbb; blood; brain; cells; cns; cocaine; coronavirus; cov-2; covid-19; cytokines; disease; expression; hpa; infection; patients; protein; responses; sars; system; use; virus
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        item: #5964 of 7819
          id: cord-332110-6fmc5mbs
      author: Drury, John
       title: COVID‐19 in context: Why do people die in emergencies? It’s probably not because of collective psychology
        date: 2020-06-16
       words: 3241
      flesch: 51
     summary: In short, Hillsborough, like Cocoanut Grove, did not happen because of failings at the level of collective psychology. In these cases, then, the emergency ends badly due to the absence of collective psychology (i.e., lack of coordination and cooperation).
    keywords: collective; covid-19; emergencies; people; psychology; public; risk
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        item: #5965 of 7819
          id: cord-332118-jg80szw7
      author: Sánchez-Sánchez, Eduardo
       title: Eating Habits and Physical Activity of the Spanish Population during the COVID-19 Pandemic Period
        date: 2020-09-15
       words: 4371
      flesch: 49
     summary: COVID-19 (SARS-COV2) pandemic: Physical exercise and behavior-based approach Effects of COVID-19 home confinement on eating behaviour and physical activity: Results of the ECLB-COVID19 international online survey Positive and negative changes in food habits, physical activity patterns, and weight status during COVID-19 confinement: Associated factors in the chilean population We appreciate all the people that has collaborated in this project through their participation and the dissemination of the questionnaire. The increase in the number of sessions offset the time reduction, as the suggested objective for people who remained at home due to COVID-19 confinement could be achieved (150 min per week)
    keywords: activity; adherence; confinement; consumption; covid-19; study; subjects
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        item: #5966 of 7819
          id: cord-332145-rw16o02g
      author: Chen, Patrick M.
       title: Evolving Healthcare Delivery in Neurology During the Coronavirus Disease 2019 (COVID-19) Pandemic
        date: 2020-05-29
       words: 2969
      flesch: 39
     summary: An important task moving forward is to be methodical in our collection of data for COVID-19 neurologic patients if we are the truly understand its role in the central nervous system. Acute stroke alerts present the most direct potential interface with COVID-19 patients.
    keywords: care; covid-19; disease; hospital; pandemic; patients; risk; stroke; telemedicine
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        item: #5967 of 7819
          id: cord-332150-j76726no
      author: De Stefano, Ludovico
       title: A “Window of Therapeutic Opportunity” for Anti-Cytokine Therapy in Patients With Coronavirus Disease 2019
        date: 2020-10-06
       words: 3623
      flesch: 9
     summary: Microorganisms Efficacy and safety of tocilizumab in severe COVID-19 patients: a singlecentre retrospective cohort study Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized COVID-19 Patients: Survival and Clinical Outcomes Profiling COVID-19 pneumonia progressing into the cytokine storm syndrome: Results from a single Italian Centre study on tocilizumab versus standard of care Safety and efficacy of anti-il6-receptor tocilizumab use in severe and critical patients affected by coronavirus disease 2019: A comparative analysis Early use of low dose tocilizumab in patients with COVID-19: A retrospective cohort study with a complete follow-up Tocilizumab in patients with severe COVID-19: a retrospective cohort study Tocilizumab among patients with COVID-19 in the intensive care unit: a multicentre observational study Interleukin-6 blockade with sarilumab in severe COVID-19 pneumonia with systemic hyperinflammation: an open-label cohort study Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study Anakinra for severe forms of COVID-19: a cohort study Beneficial impact of Baricitinib in COVID-19 moderate pneumonia; multicentre study Efficacy Evaluation of Early, Low-Dose, Short-Term Corticosteroids in Adults Hospitalized with Non-Severe COVID-19 Pneumonia: A Retrospective Cohort Study Effect of Systemic Glucocorticoids on Mortality or Mechanical Ventilation in Patients With COVID-19 Factors associated with COVID-19-related death using OpenSAFELY The role of host genetics in the immune response to SARS-CoV-2 and COVID-19 susceptibility and severity Mannose-binding lectin in severe acute respiratory syndrome coronavirus infection Viral and host factors related to the clinical outcome of COVID-19 Hypothesis for potential pathogenesis of SARSCoV-2 infection -a review of immune changes in patients with viral pneumonia COVID-19: immunopathology and its implications for therapy The Many Faces of the anti-COVID Immune Response Clinical and immunologic features in severe and moderate forms of Coronavirus Disease SARS-CoV-2 infects T lymphocytes through its spike protein-mediated membrane fusion Functional exhaustion of antiviral lymphocytes in COVID-19 patients Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus.
    keywords: covid-19; cytokine; disease; patients; sars; study; syndrome; tocilizumab
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        item: #5968 of 7819
          id: cord-332153-fczf3lzc
      author: Azkur, Ahmet Kursat
       title: Immune response to SARS‐CoV‐2 and mechanisms of immunopathological changes in COVID‐19
        date: 2020-05-12
       words: 6190
      flesch: 41
     summary: Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Cell-free hemoglobin: a novel mediator of acute lung injury The Acute Respiratory Distress Syndrome: Mechanisms and Perspective Therapeutic Approaches Management of Critically Ill Adults With COVID-19 Treatment for severe acute respiratory distress syndrome from COVID-19 Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma An inhaled tumor necrosis factor-alpha-derived TIP peptide improves the pulmonary function in experimental lung injury The clinical pathology of severe acute respiratory syndrome (SARS): a report from Immunohistochemical, and Ultrastructural Findings of a Fatal Case of Middle East Respiratory Syndrome Coronavirus Infection in the United Arab Emirates Autopsy in suspected COVID-19 cases Pulmonary Pathology of Early-Phase 2019 Novel Coronavirus (COVID-19) Pneumonia in Two Patients With Lung Cancer Histopathologic Changes and SARS-CoV-2 Immunostaining in the Lung of a Patient With COVID-19 Clinical characteristics of 25 death cases with COVID-19: a retrospective review of medical records in a single medical center Liver impairment in COVID-19 patients: a retrospective analysis of 115 cases from a single center in Wuhan city Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 (COVID-19) in Wuhan, China: a retrospective study Procalcitonin in patients with severe coronavirus disease 2019 (COVID-19): A meta-analysis Kidney disease is associated with in-hospital death of patients with COVID-19 Accepted Article 15 Anticoagulation therapy is recommended for COVID-19 patients, when the D- This article is protected by copyright.
    keywords: acute; article; cells; copyright; coronavirus; cov-2; covid-19; cytokine; disease; patients; rights; sars; storm
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        item: #5969 of 7819
          id: cord-332160-dytr70pi
      author: Wang, Biao
       title: The Role of Spine Surgeons in the Era of COVID-19 Outbreak
        date: 2020-05-18
       words: 510
      flesch: 52
     summary: Spine surgeons are competent for the treatment of light patients, and can carry out diagnosis and treatment in the isolation ward of light patients or similar shelter hospitals. As a member of the medical staff, spine surgeons have also played an important role in this campaign.
    keywords: patients; spine
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        item: #5970 of 7819
          id: cord-332175-d5suvj8g
      author: Allen, Jawara
       title: My Future in Medicine: How COVID-19 Is Inspiring the Next Generation of Infectious Disease Specialists
        date: 2020-04-11
       words: 1249
      flesch: 54
     summary: But the importance of infectious disease specialists will not end once the number of newly diagnosed COVID-19 cases starts to decrease. During this pandemic, the role of infectious disease specialists as leaders has become evident; they are top-tier advisors to policy makers, public health practitioners disseminating health information to society, researchers identifying treatments and vaccines for the virus, and front-line clinicians treating the most vulnerable patients.
    keywords: covid-19; disease; health; healthcare
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        item: #5971 of 7819
          id: cord-332179-du1zjupf
      author: Sayed, Shomoita
       title: COVID-19 and Diabetes; possible role of polymorphism and rise of telemedicine
        date: 2020-08-31
       words: 4017
      flesch: 42
     summary: A wide-range study in England recorded 1.5% deaths of T1D patients among a total of 23,804 COVID-19 deaths. There was a very conspicuous relationship between deprivation and T1D mortality indicated by 29•6% deaths in the most deprived quintile and only 10•4% deaths in the least deprived quintile among T1D patients [17] .
    keywords: ace2; angiotensin; cov-2; covid-19; diabetes; infection; patients; sars; study; t1d; type
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        item: #5972 of 7819
          id: cord-332180-dw4h69tp
      author: Cheng, Fu-Yuan
       title: Using Machine Learning to Predict ICU Transfer in Hospitalized COVID-19 Patients
        date: 2020-06-01
       words: 4130
      flesch: 39
     summary: The non-ICU bed to ICU transfer rate in our cohort was 3.7 percent, which created an extreme class imbalance between the majority class (feature vectors without the occurrence of ICU transfer within 24 h) and the minority class (feature vectors with ICU transfer within 24 h). Low sample size and class imbalance resulting from low ICU transfer rates are major limitations to this version of the model, which resulted in low precision.
    keywords: care; cohort; covid-19; data; icu; model; patients; risk; transfer; variables
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        item: #5973 of 7819
          id: cord-332194-97tkyv3w
      author: Barrett, Peter M
       title: Measuring the effectiveness of an automated text messaging active surveillance system for COVID-19 in the south of Ireland, March to April 2020
        date: 2020-06-11
       words: 1995
      flesch: 49
     summary: key: cord-332194-97tkyv3w authors: Barrett, Peter M; Bambury, Niamh; Kelly, Louise; Condon, Rosalind; Crompton, Janice; Sheahan, Anne title: Measuring the effectiveness of an automated text messaging active surveillance system for COVID-19 in the south of Ireland, March to April 2020 date: 2020-06-11 journal: Euro Surveill DOI: 10.2807/1560-7917.es.2020.25.23.2000972 sha: doc_id: 332194 cord_uid: 97tkyv3w We report the effectiveness of automated text messaging for active surveillance of asymptomatic close contacts of coronavirus disease (COVID-19) cases in the Cork/Kerry region of Ireland. However, evidence for the effectiveness of active surveillance systems among community-based close contacts of cases of COVID-19 has been limited to date.
    keywords: contacts; covid-19; surveillance; testing; text
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        item: #5974 of 7819
          id: cord-332204-24e2kcas
      author: Post, Adrian
       title: Is low sodium intake a risk factor for severe and fatal COVID-19 infection?
        date: 2020-04-08
       words: 416
      flesch: 31
     summary: It seems wise to monitor sodium intake and start with sodium and fluid resuscitation early in the course of more severe COVID-19 infection, and perhaps also to refrain from robust sodium restriction during the current COVID-19 outbreak. key: cord-332204-24e2kcas authors: Post, Adrian; Dullaart, Robin P.F.; Bakker, Stephan J.L. title: Is low sodium intake a risk factor for severe and fatal COVID-19 infection? date: 2020-04-08 journal:
    keywords: covid-19; sodium
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        item: #5975 of 7819
          id: cord-332218-4bumy47f
      author: Rosenthal, Jamie A.
       title: Asthma Is Associated with Increased Risk of Intubation but Not Hospitalization or Death in COVID-19
        date: 2020-10-12
       words: 696
      flesch: 48
     summary: While studies from China suggested that 3 asthma was not a risk factor for severe COVID-19, other studies have shown higher rates of asthma 4 among hospitalized patients 1, 2 . This study assessed whether asthma was associated with COVID-19 severity with regards to outcomes 57 and laboratory biomarkers.
    keywords: asthma; covid-19
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        item: #5976 of 7819
          id: cord-332234-6jursf4h
      author: Diaferio, Lucia
       title: Cross-sectional survey on impact of paediatric COVID-19 among Italian paediatricians: report from the SIAIP rhino-sinusitis and conjunctivitis committee
        date: 2020-10-06
       words: 2397
      flesch: 49
     summary: The questionnaire was conceived and pretested in April 2020, by a working group of experts of the Italian Paediatric Society for Allergy and Immunology (SIAIP) based on their personal clinical experience and on the extensive review of most relevant international literature on COVID-19 infection searched on MEDLINE, EMBASE and SCOPUS. Actually, data on COVID-19 in Italian children are limited and almost certainly underestimated, since they are frequently asymptomatic or presenting mild or moderate infection, similar to common cold.
    keywords: asthma; children; covid-19; patients; survey
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        item: #5977 of 7819
          id: cord-332241-rvvzl6y1
      author: Chen, Tz‐Heng
       title: The advantages of peritoneal dialysis over hemodialysis during the COVID‐19 pandemic
        date: 2020-07-16
       words: 1043
      flesch: 36
     summary: Moreover, a very high proportion of dialysis patients are the elderly or patients with multiple comorbidities. When inpatient HD units become a resource-constrained environment, alternative therapeutic strategies for dialysis patients should be considered.
    keywords: covid-19; dialysis; patients
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        item: #5978 of 7819
          id: cord-332245-yfj1kkj7
      author: None
       title: SARS-CoV-2 Infektion bei Kindern und Jugendlichen: Ein Literaturüberblick der AG Infektiologie der ÖGKJ1
        date: 2020-06-10
       words: 2343
      flesch: 49
     summary: Inwieweit sich Inkubationszeit und Erkrankungsdauer bei Kindern von denjenigen bei Erwachsenen unterscheiden, ist noch nicht ausreichend untersucht Ende April wurde in England eine Warnmeldung aufgrund vermehrter Fälle von Kindern mit einem ungewöhnlichen Inflammationssyndrom veröffentlicht.
    keywords: auch; bei; china; coronavirus; cov-2; covid-19; der; die; eine; ist; kindern; mit; nicht; oder; sars; sind; und; von; werden
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        item: #5979 of 7819
          id: cord-332268-x30svp5y
      author: Bearden, Donna M.
       title: COVID-19: a primer for healthcare providers
        date: 2020-05-20
       words: 3706
      flesch: 47
     summary: In fact, the use of methylprednisolone as an intervention for SARS patients was associated with a higher 30-day mortality rate [1] . A randomized, placebo-controlled study of SARS patients suggested that those given steroids early in the infection developed prolonged viremia.
    keywords: china; coronavirus; covid-19; disease; mers; novel; patients; sars; spread
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        item: #5980 of 7819
          id: cord-332292-n7k4va9k
      author: Yen, Yung-Feng
       title: Olfactory disorder in patients infected with SARS-CoV-2
        date: 2020-08-20
       words: 1244
      flesch: 50
     summary: key: cord-332292-n7k4va9k authors: Yen, Yung-Feng; Lai, Hsin-Hao; Chan, Shang-Yih; Yi-Fong Su, Vincent; Chiu, Ting-Fang; Huang, Chiao-Yu; Hung, Chia-Chun; Kuo, Tzu-Ling; Lee, Ya-Ling; Chu, Dachen title: Olfactory disorder in patients infected with SARS-CoV-2 date: 2020-08-20 journal: J Microbiol Immunol Infect DOI: 10.1016/j.jmii.2020.08.010 sha: doc_id: 332292 cord_uid: n7k4va9k Abstract Three (60%) of five patients with coronavirus disease 2019 (COVID-19) had olfactory disorder. According to two cross-sectional studies, the prevalence of olfactory disorder in COVID-19 patients ranged from 23.7% to 85.6%.
    keywords: covid-19; disorder; olfactory; patients
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        item: #5981 of 7819
          id: cord-332314-nukv34fh
      author: Bartoszek, Krzysztof
       title: Are official confirmed cases and fatalities counts good enough to study the COVID-19 pandemic dynamics? A critical assessment through the case of Italy
        date: 2020-06-26
       words: 5615
      flesch: 54
     summary: Hence, calibrating model parameters for this virus’s dynamics should not be done based only on confirmed case counts (without rescaling by the number of tests), but take also fatalities and hospitalization count under consideration as variables not prone to be distorted by testing efforts. Hence, calibrating model parameters for this virus's dynamics should not be done based only on confirmed case counts (without rescaling by the number of tests), but take also fatalities and hospitalization count under consideration as variables not prone to be distorted by testing efforts.
    keywords: case; counts; covid-19; data; fatalities; italy; number; regions; tests; time
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        item: #5982 of 7819
          id: cord-332333-vw5ogccq
      author: Montenegro-López, Diego
       title: Uso de tecnologías en el lugar de atención para el manejo de la pandemia por COVID-19 en Colombia
        date: 2020-08-14
       words: 3007
      flesch: 40
     summary: en Colombia Detección Temprana SARS CoV-2/ COVID-19 MInisterio de Salud y de la Proteccion Social Colombia: 25 de marzo 2020 Guidelines for point-of-care testing: Según el reporte de la Procuraduría de Colombia (40), el costo de cada PCR es de 380 mil pesos colombianos (aprox.
    keywords: atención; casos; colombia; con; coronavirus; covid-19; del; diagnóstico; las; los; para; pcr; por; pruebas; que; rápido; salud; una
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        item: #5983 of 7819
          id: cord-332348-yi85sfks
      author: Liang, Yujie
       title: Neurosensory dysfunction: a diagnostic marker of early COVID-19
        date: 2020-06-29
       words: 2751
      flesch: 52
     summary: However, no difference was noted in viral load between patients with and without neurosensory dysfunction, suggesting that the effect of viral load on the development of neurosensory dysfunction varies. key: cord-332348-yi85sfks authors: Liang, Yujie; Xu, Jiabin; Chu, Mei; Mai, Jianbo; Lai, Niangmei; Tang, Wen; Yang, Tuanjie; Zhang, Sien; Guan, Chenyu; Zhong, Fan; Yang, Liuping; Liao, Guiqing title: Neurosensory dysfunction: a diagnostic marker of early COVID-19 date: 2020-06-29 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.06.086 sha: doc_id: 332348 cord_uid: yi85sfks Abstract Objectives To detailly described the neurosensory dysfunction, including hyposmia, hypogeusia and tinnitus, in patients with COVID-19.
    keywords: covid-19; dysfunction; load; onset; patients; study
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        item: #5984 of 7819
          id: cord-332373-yqcysn27
      author: Lingamaneni, Prasanth
       title: Heparin-Induced Thrombocytopenia in COVID-19
        date: 2020-07-28
       words: 1883
      flesch: 41
     summary: 10 Antiphospholipid syndrome has been reported in COVID-19 patients, 11 and these patients often test false positive with HIT serology. 6 In those with intermediate or high pretest probability, testing for the presence of HIT antibodies should be done, by using immunoassays or platelet activation assays.
    keywords: covid-19; heparin; hit; patients; thrombocytopenia
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        item: #5985 of 7819
          id: cord-332420-9vyik2e9
      author: Probst, Thomas
       title: Being a Psychotherapist in Times of the Novel Coronavirus Disease: Stress-Level, Job Anxiety, and Fear of Coronavirus Disease Infection in More Than 1,500 Psychotherapists in Austria
        date: 2020-09-29
       words: 5011
      flesch: 42
     summary: Means and SDs are shown in Table 3 . Psychotherapists with more reductions in the total (face-toface + telephone + internet) number of patients treated on average per week in COVID-19 as compared to the months before experienced comparable stress-level, r = −0.006, p = 0.818, as well as comparable job-related worries and fears of existence, r = −0.011, p = 0.660, as psychotherapists with less reductions in the total number of patients treated on average per week. Psychotherapists still practicing face-to-face during the COVID-19 lockdown had lower fear of COVID-19 infection during face-to-face psychotherapy than psychotherapists not practicing face-to-face during COVID-19.
    keywords: covid-19; face; fears; job; psychotherapists; psychotherapy; stress
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        item: #5986 of 7819
          id: cord-332454-fays5l5d
      author: Casas-Rojo, J M
       title: Características clínicas de los pacientes hospitalizados con COVID-19 en España: resultados del Registro SEMI-COVID-19
        date: 2020-07-19
       words: 3290
      flesch: 48
     summary: Se analizan datos demográficos, clínicos, epidemiológicos, de laboratorio y de imagen diagnóstica de los pacientes participantes, así como su evolución clínica. España ha sido uno de los países más afectados por la pandemia de COVID-19.
    keywords: como; con; covid-19; datos; del; españa; fueron; ingreso; las; los; más; pacientes; para; patients; por; que; registro; uci; una
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        item: #5987 of 7819
          id: cord-332480-3uodkrkp
      author: Bonam, Srinivasa Reddy
       title: Adjunct immunotherapies for the management of severely ill COVID-19 patients
        date: 2020-04-30
       words: 5451
      flesch: 35
     summary: 12, 13 Plasma obtained from COVID-19 patients, in particular moribund patients, demonstrated increased concentrations of various inflammation-related cytokines and chemokines implicated in the recruitment of immune cells including interleukin (IL)-1β, tumor necrosis factor (TNF)-α, IL-2, IL-6, IL-7, IL-8, IL-9, IL-17, granulocyte-colony stimulating factor (G-CSF), granulocytemacrophage colony-stimulating factor (GM-CSF), interferon (IFN)-γ, C-X-C motif chemokine 10 (CXCL10), chemokine ligand 2 (CCL2), CCL3 and CCL4. 1, 14, 15 In addition, COVID-19 patients showed relatively increased neutrophil counts in the blood.
    keywords: antibody; cells; cov-2; covid-19; disease; patients; plasma; sars; syndrome; therapy; treatment; viral
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        item: #5988 of 7819
          id: cord-332481-y0rd70ry
      author: Ljubic, T.
       title: The effect of serological screening for SARS-CoV-2 antibodies to participants' attitudes and risk behaviour: a study on a tested population sample of industry workers in Split-Dalmatia County, Croatia
        date: 2020-06-17
       words: 3849
      flesch: 41
     summary: Therefore, our study aimed to investigate the changes in personal attitudes and behaviour before and after negative serological test results for SARS-CoV-2 antibodies. Thus, this study aims at investigating the changes in personal attitudes and behaviour of DIV Group industry workers before and after receiving negative serological test results for SARS-CoV-2 antibodies.
    keywords: behaviour; covid-19; measures; participants; results; testing
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        item: #5989 of 7819
          id: cord-332496-xxz6qd3i
      author: Jiménez, Óliver
       title: Psychological Impact of COVID-19 Confinement and Its Relationship with Meditation
        date: 2020-09-11
       words: 3916
      flesch: 41
     summary: The sociodemographic variables that had the strongest relationship with psychological impact were being under treatment or not, age, and quality of cohabitation during the quarantine, indicating that not being under any treatment implied lower scores of Intrusion and Avoidance. Being young was related to higher scores of stress and depression, in agreement with recent studies on the psychological impact, relating age and being a student with higher vulnerability and psychological impact from confinement
    keywords: compassion; covid-19; impact; scale; self; stress; variables
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        item: #5990 of 7819
          id: cord-332503-3h4fovqx
      author: Hui, Dawn S.
       title: On ventricular aneurysms, thrombi, and COVID-19
        date: 2020-10-09
       words: 378
      flesch: 43
     summary: f The Annals of Thoracic Surgery Please cite this article as: Hui DS, Calhoon JH, On ventricular aneurysms, thrombi, and COVID-19 Left ventricular reconstruction with trombectomy How to do it: surgical decision making for left ventricular aneurysmectomy Surgical ventricular reconstruction with endocardectomy along radiofrequency ablation-induced markings ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub Ventricular thrombi have been described as one manifestation, including biventricular thrombi complicating J o u r n a l P r e -p r o o
    keywords: covid-19; ventricular
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        item: #5991 of 7819
          id: cord-332541-mntietmw
      author: Yang, Tianan
       title: Lessons Learnt from China: National Multidisciplinary Healthcare Assistance
        date: 2020-09-30
       words: 1283
      flesch: 35
     summary: Second, a holistic governance model should be constructed to promote information disclosure, public understanding, resource complementarity, and risk-sharing among stakeholders, in order to ensure the proper implementation of public health policies for such crises. The national health commission of the People's Republic of China has established a mechanism for interprovincial support to the prevention and treatment of COVID-19 in cities other than Wuhan in Hubei province Methods for evaluating changes in health care policy: the difference-in-differences approach National Health Commission of the People's Republic of China.
    keywords: china; healthcare; national; policy
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        item: #5992 of 7819
          id: cord-332547-m9mb3c22
      author: Iravani, Behzad
       title: Relationship Between Odor Intensity Estimates and COVID-19 Prevalence Prediction in a Swedish Population
        date: 2020-05-22
       words: 5680
      flesch: 39
     summary: Moreover, the more symptoms the individual reported, the weaker the odors were perceived as, as demonstrated by a Spearman correlation between the number of reported COVID-19 symptoms and odor intensity ratings, ρ = −0.29, P < 0.001 ( Figure 2 ). Moreover, we found that there was a large difference in rated intensity between individuals with and without COVID-19 symptoms and the number of symptoms was related to odor intensity ratings.
    keywords: covid-19; dysfunction; individuals; intensity; odor; olfactory; population; prevalence; ratings; symptoms
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        item: #5993 of 7819
          id: cord-332559-2r2gavbq
      author: Kajdy, Anna
       title: Risk factors for anxiety and depression among pregnant women during the COVID-19 pandemic: A web-based cross-sectional survey
        date: 2020-07-24
       words: 5211
      flesch: 46
     summary: key: cord-332559-2r2gavbq authors: Kajdy, Anna; Feduniw, Stepan; Ajdacka, Urszula; Modzelewski, Jan; Baranowska, Barbara; Sys, Dorota; Pokropek, Artur; Pawlicka, Paulina; Kaźmierczak, Maria; Rabijewski, Michał; Jasiak, Hanna; Lewandowska, Roksana; Borowski, Dariusz; Kwiatkowski, Sebastian; Poon, Liona C. title: Risk factors for anxiety and depression among pregnant women during the COVID-19 pandemic: A web-based cross-sectional survey date: 2020-07-24 journal: Medicine (Baltimore) DOI: 10.1097/md.0000000000021279 sha: doc_id: 332559 cord_uid: 2r2gavbq INTRODUCTION: The article presents a protocol of a cross-sectional study of mental health of pregnant women in relation to the coronavirus disease 19 (COVID-19) pandemic.
    keywords: anxiety; covid-19; data; depression; health; pandemic; pregnancy; questions; study; survey; women
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        item: #5994 of 7819
          id: cord-332561-n2ghm318
      author: Noordzij, Marlies
       title: ERACODA: the European database collecting clinical information of patients on kidney replacement therapy with COVID-19
        date: 2020-08-12
       words: 1712
      flesch: 43
     summary: Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Kidney disease is associated with in-hospital death of patients with COVID-19 Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study Covid-19 and kidney transplantation Immunology of COVID-19: current state of the science Imbalanced host response to SARS-CoV-2 drives development of COVID-19 Associations between immunesuppressive and stimulating drugs and novel COVID-19-a systematic review of current evidence A global clinical measure of fitness and frailty in elderly people Children of a lesser god: exclusion of chronic kidney disease patients from clinical trials However, KRT patients are well aware of their elevated risk and may have adjusted their behaviour, regarding hygiene and social distancing, accordingly.
    keywords: covid-19; data; eracoda; kidney; patients
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        item: #5995 of 7819
          id: cord-332573-pltz5viz
      author: Lieberman, Joshua A
       title: Coping With COVID-19: Emerging Medical Student Clinical Pathology Education in the Pacific Northwest in the Face of a Global Pandemic
        date: 2020-09-02
       words: 3785
      flesch: 39
     summary: The effects of COVID-19 on academic activities and surgical education in Italy Residency and fellowship program accreditation: effects of the novel coronavirus (COVID-19) pandemic [published Blended learning via distance in pre-registration nursing education: a scoping review Implementing a structured digitalbased online pathology curriculum for trainees at the time of COVID-19 Leveraging technology for remote learning in the era of COVID-19 and social distancing: tips and resources for pathology educators and trainees Self-regulated learning: the effect on medical student learning outcomes in a flipped classroom environment Analysis of satisfaction and academic achievement of medical students in a flipped class Informatics training for pathology practice and research in the digital era Daily medical education for confined students during COVID-19 pandemic: a simple videoconference solution Blood bank guy Transfusion medicine questions The coronavirus pandemic made Zoom the most popular app, and that came with consequences VOIP for telerehabilitation: a risk analysis for privacy, security, and HIPAA compliance COVID-19: states call on early medical school grads to bolster workforce Itching to get back in: medical students graduate early to join the fight. The Department of Laboratory Medicine routinely offers two 2-week clerkships for medical students: Laboratory Medicine 685: Laboratory Case Studies for Clinical Diagnosis (LabM 685) and Laboratory Medicine 680: Clinical Laboratory Testing-Methods and Interpretation (LabM 680).
    keywords: course; covid-19; education; labm; laboratory; learning; medical; medicine; students
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        item: #5996 of 7819
          id: cord-332577-2z5pchyq
      author: Adolph, C.
       title: Governor partisanship explains the adoption of statewide mandates to wear face coverings
        date: 2020-09-02
       words: 6222
      flesch: 51
     summary: Using originally collected data on mask mandates across states, we examine how differences in COVID-19 indicators, state capacity, and partisan politics may have affected the speed of mask mandate adoption. To further capture variation across mask mandates applying to the general public, we create a typology with three ordered categories that encompass all state-wide public mask mandates issued over this period: Limited mandate (Level 1).
    keywords: covid-19; deaths; level; license; mandates; mask; medrxiv; preprint; public; state
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        item: #5997 of 7819
          id: cord-332579-7950xjmv
      author: Aravena, J. M.
       title: 'Drawing on Wisdom to Cope with Adversity:' A Systematic Review Protocol of Older Adults' Mental and Psychosocial Health During Acute Respiratory Disease Propagated-Type Epidemics and Pandemics (COVID-19, SARS-CoV, MERS, and Influenza).
        date: 2020-06-07
       words: 5013
      flesch: 37
     summary: In this context, and considering the increasing number of COVID-19 related articles, a systematic review targeted to older people mental health considering a full-range of neuropsychiatric, psychiatric, psychosocial, and wellbeing parameters associated with the infection or the contextual impacts related to acute respiratory disease propagated-type epidemics and pandemics, contrasting the results among groups seems pertinent and necessary to fully understand the response and experiences of older adults and other age groups in the context of pandemics. . 34, 35 Studies will be divided into two main categories for its analysis: 1) studies describing the direct effect of virus infection on mental health outcomes, and 2) studies illustrating mental health impact associated with the contextual situation of the epidemic or pandemic (e.g. quarantines, social distancing, isolation).
    keywords: adults; covid-19; data; groups; health; pandemics; psychosocial; studies; study; type
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        item: #5998 of 7819
          id: cord-332592-bfqsyiyf
      author: Goette, Andreas
       title: COVID-19-Induced Cytokine Release Syndrome Associated with Pulmonary Vein Thromboses, Atrial Cardiomyopathy, and Arterial Intima Inflammation
        date: 2020-09-26
       words: 3547
      flesch: 33
     summary: A report of COVID-19 patients in China found elevated plasma concentrations of inflammatory markers in particular in patients with severe infections. Current concepts in the diagnosis and management of cytokine release syndrome Cytokine release from human peripheral blood leucocytes incubated with endotoxin with and without prior infection with influenza virus: relevance to the sudden infant death syndrome Porcine reproductive and respiratory syndrome virus infection triggers HMGB1 release to promote inflammatory cytokine production COVID-19: a new virus, but a familiar receptor and cytokine release syndrome Cytokine release syndrome in severe COVID-19 Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality Postmortem examination of patients with COVID-19 ECMO for ARDS due to COVID-19 The ABO blood group locus and a chromosome 3 gene cluster associate with SARS CoV-2 respiratory failure in an Italian-Spanish genome-wide association analysis Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past The procoagulant pattern of patients with COVID-19 acute respiratory distress syndrome Activated clotting factor X mediates mitochondrial alterations and inflammatory responses via protease-activated receptor signaling in alveolar epithelial cells Will complement inhibition be the new target in treating COVID-19-related systemic thrombosis?
    keywords: cov-2; covid-19; fig; patients; present; pulmonary; sars; syndrome
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        item: #5999 of 7819
          id: cord-332625-3rvis2gy
      author: Modell, Stephen M.
       title: Religion as a Health Promoter During the 2019/2020 COVID Outbreak: View from Detroit
        date: 2020-06-16
       words: 5399
      flesch: 48
     summary: In public health, we consider health promotion to be mediated by health facilitators and deterred by health barriers, which are often physical factors or people advocating for health (Kieffer et al. 2005, p. 149 ). … In spite of the enormous difficulties involved, the ethical imperative from the Orthodox perspective calls for the widest distribution of health care and life-protecting resources facilities and resources, rather than a concentration of such resources for the select few (Harakas 1980, pp. 26-27) .
    keywords: city; community; coronavirus; covid-19; detroit; diabetes; disease; factors; faith; health; level; pandemic; people; public; risk
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        item: #6000 of 7819
          id: cord-332650-05oz5zwz
      author: Fiorelli, Silvia
       title: Perspectives in surgical and anaesthetic management of lung cancer in the era of coronavirus disease 2019 (COVID-19)
        date: 2020-08-26
       words: 3277
      flesch: 33
     summary: Alternatively, some hospitals should be committed to treating COVID-19 patients exclusively (hub hospitals), whereas other medical centres can continue to treat ordinary non-infected cases (COVID-19-free spoke hospitals) Particulate respirators, designed to block 95-99% of aerosol particles and recommended during management of COVID-19 patients, should be routinely used during thoracic anaesthesia.
    keywords: cancer; covid-19; lung; management; pandemic; patients; surgery; thoracic
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        item: #6001 of 7819
          id: cord-332673-av2vt54r
      author: Alwashmi, Meshari F.
       title: The Use of Digital Health in the Detection and Management of COVID-19
        date: 2020-04-23
       words: 3023
      flesch: 42
     summary: Carbon Health At Home Medical Testing Kits Update: FDA Alerts Consumers About Unauthorized Fraudulent COVID-19 Test Kits Relationship to Duration of Infection Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review Abu Ashour, W. The Effect of Smartphone Interventions on Patients with Chronic Obstructive Pulmonary Disease Exacerbations: A Systematic Review and Meta-Analysis Impact of remote patient monitoring on clinical outcomes: An updated meta-analysis of randomized controlled trials Remote Sensing of Vital Signs: A Wearable, Wireless Band-Aid Sensor with Personalized Analytics for Improved Ebola Patient Care and Worker Safety Type 2 Diabetes and its Impact on the Immune System Use of a mobile application for Ebola contact tracing and monitoring in northern Sierra Leone: A proof-of-concept study TraceTogether-Behind the Scenes Look at Its Development Process. To assist in COVID-19 contact tracing, a mobile app called TraceTogether is currently being used in Singapore
    keywords: covid-19; diseases; health; healthcare; monitoring; patients; potential; screening
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        item: #6002 of 7819
          id: cord-332678-yk1stlty
      author: Baldacini, Mathieu
       title: Concomitant haemorrhagic syndrome and recurrent extensive arterial thrombosis in a patient with COVID‐19 and acute promyelocytic leukaemia
        date: 2020-05-26
       words: 1048
      flesch: 37
     summary: Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia Mechanisms and management of coagulopathy in acute promyelocytic leukemia COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up COVID-19 coagulopathy in Caucasian patients Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia High risk of thrombosis in patients in severe SARS-CoV-2 infection: a multicenter prospective cohort study Thromboembolic risk and anticoagulant therapy in COVID-19 patients: emerging evidence and call for action High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients We present here the multiple haemostasis abnormalities observed in a patient with concomitant acute promyelocytic leukaemia and COVID-19.
    keywords: covid-19; leukaemia; patient; promyelocytic
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        item: #6003 of 7819
          id: cord-332680-zfn81hew
      author: Chan, Chieh-Kai
       title: Renin-Angiotensin-Aldosterone System Inhibitors and Risks of Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Systematic Review and Meta-Analysis
        date: 2020-09-10
       words: 4305
      flesch: 38
     summary: The following variables were extracted: author, journal, publication year, study design, geographic location, participants' details (number, study population, age, sex, and comorbidities, including hypertension, diabetes mellitus, heart failure, and chronic kidney disease), use of antihypertensive drugs, such as ACE inhibitors, ARBs, calcium-channel blockers, beta-blockers, diuretics, outcomes (including positive SARS-CoV-2 test results and disease prognosis/severity, if available). Age has consistently been reported to be a common risk attributing to COVID-19 infection and its related mortality.
    keywords: ace; arbs; cov-2; covid-19; infection; inhibitors; risk; sars; studies
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        item: #6004 of 7819
          id: cord-332682-c6iql84p
      author: Liesman, Daniel R
       title: Perspectives From Rising Fourth Year Medical Students Regarding Strategies to Counteract the Effects of COVID-19 on Medical Education
        date: 2020-07-13
       words: 2116
      flesch: 35
     summary: We, as rising fourth-year medical students, would like to shed light upon the hard work that many of those in leadership positions have done as well as lay out some concerns that medical students who are preparing to apply to residency have. Medical students and administrators across the country are currently faced with the difficult and harsh realities of the COVID-19 pandemic.
    keywords: covid-19; medical; residency; rotations; students
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        item: #6005 of 7819
          id: cord-332703-ohzkpbwy
      author: Hui, Jane Yuet Ching
       title: Cancer Management During the COVID-19 Pandemic in the United States: Results From a National Physician Cross-sectional Survey
        date: 2020-08-25
       words: 3512
      flesch: 41
     summary: 17 Measures Survey items included demographics and measures of clinical practice size and location, personal concerns about COVID-19, effects of COVID-19 pandemic on cancer patient treatment, sources of information about COVID-19, and emotional health. Most physicians (N=285; 70.0% of surgeons, 64.4% of medical oncologists, and 73.4% of radiation oncologists) had altered cancer treatment plans.
    keywords: cancer; covid-19; oncologists; patients; physicians; plans; states; treatment
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        item: #6006 of 7819
          id: cord-332709-0plblo4k
      author: Zodda, David
       title: Optimizing Non-invasive Oxygenation for COVID-19 Patients Presenting to the Emergency Department with Acute Respiratory Distress: A Case Report
        date: 2020-06-22
       words: 2378
      flesch: 46
     summary: With limited resources and ventilators available, emergency physicians working at a hospital within the epicenter of the United States outbreak developed a stepwise, non-invasive oxygenation strategy for treating COVID-19 patients presenting with severe hypoxia and acute respiratory distress. Our case highlights a stepwise, organized approach to providing non-invasive oxygenation for COVID-19 patients presenting with severe hypoxia and acute respiratory distress.
    keywords: covid-19; non; oxygen; oxygenation; patients
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        item: #6007 of 7819
          id: cord-332716-1d89j7jh
      author: Choi, Marcelo
       title: El SRAA y el SARS-CoV-2: el acertijo a resolver
        date: 2020-05-27
       words: 3340
      flesch: 38
     summary: En términos de beneficios en la evolución de la enfermedad por COVID-19, el estudio de Mehra MR y cols. Existe un gran interés en dilucidar la función de ECA2 en la enfermedad cardiovascular, tanto el de la enzima transmembrana como también el de la forma soluble.
    keywords: ang; angiotensin; con; converting; covid-19; del; eca2; enzyme; los; niveles; por; proteína; que; receptor; sars; una
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        item: #6008 of 7819
          id: cord-332729-f1e334g0
      author: Shah, Nirav R.
       title: An Impact-Oriented Approach to Epidemiological Modeling
        date: 2020-09-21
       words: 1639
      flesch: 46
     summary: Those who develop epidemiological models are no longer only creating specialty tools, but consumer products as well, and thus face a new, non-traditional, set of considerations. Traditionally, epidemiological models have been valued for their ability to inform decision-makers who possess prior knowledge of disease management.
    keywords: covid-19; data; impact; models; public
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        item: #6009 of 7819
          id: cord-332733-rnq4z2yz
      author: Su, Jinghua
       title: Proximity to people with COVID-19 and anxiety among community residents during the epidemic in Guangzhou, China
        date: 2020-07-23
       words: 1694
      flesch: 49
     summary: We collected data on participants' demographic characteristics, proximity to COVID-19 cases, time spent collecting information about coronavirus, favourite methods to obtain information, worry about COVID-19 and anxiety. Higher anxiety levels in community residents was associated with the presence of individuals with COVID-19 in the same building; a longer time spent each day gathering information about the virus; and choosing social media as their preferred source of information.
    keywords: anxiety; covid-19; information; residents
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        item: #6010 of 7819
          id: cord-332774-t5untewz
      author: Vaccaro, Alexander R.
       title: Practice Management During the COVID-19 Pandemic
        date: 2020-04-13
       words: 4905
      flesch: 44
     summary: As Pennsylvania may be one of the first states to peek, plateau, and subside with the COVID-19 surge, this puts the regional policies and group practices in position to model a restart plan. The suddenness of this mandate and the concomitant spread of the COVID-19 virus left many hospital systems, orthopaedic practices, and patients with notable anxiety and confusion as to the near, intermediate, and long-term future of our healthcare system.
    keywords: benefits; covid-19; employees; groups; office; patients; period; practice; providers; salary; staff; time
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        item: #6011 of 7819
          id: cord-332778-rf47ptj6
      author: Vivarelli, Silvia
       title: Cancer Management during COVID-19 Pandemic: Is Immune Checkpoint Inhibitors-Based Immunotherapy Harmful or Beneficial?
        date: 2020-08-10
       words: 7465
      flesch: 40
     summary: key: cord-332778-rf47ptj6 authors: Vivarelli, Silvia; Falzone, Luca; Grillo, Caterina Maria; Scandurra, Giuseppa; Torino, Francesco; Libra, Massimo title: Cancer Management during COVID-19 Pandemic: Is Immune Checkpoint Inhibitors-Based Immunotherapy Harmful or Beneficial? date: 2020-08-10 journal: Cancers (Basel) DOI: 10.3390/cancers12082237 sha: doc_id: 332778 cord_uid: rf47ptj6 The coronavirus disease 2019 (COVID-19) is currently representing a global health threat especially for fragile individuals, such as cancer patients. It was demonstrated that cancer patients have an increased risk of developing a worse symptomatology upon severe acute respiratory syndrome associated coronavirus-2 (SARS-CoV-2) infection, often leading to hospitalization and intensive care.
    keywords: cancer; cancer patients; cov-2; covid-19; icis; immune; infection; pandemic; patients; sars; study
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        item: #6012 of 7819
          id: cord-332784-xkc89uaz
      author: Mishra, Shashank Shekhar
       title: Computational investigation of potential inhibitors of novel coronavirus 2019 through structure-based virtual screening, molecular dynamics and density functional theory studies
        date: 2020-07-15
       words: 4254
      flesch: 43
     summary: The selected five potential hit molecules in the binding site of protease protein, interacting with amino acid residues Phe140, Gly143, Thr26, Thr190, Glu166, Pro168, Met165 and Leu141 with a docking score of À7.524 and À6.711 kcal/mol. The active site of COVID-19 main protease protein was located in region 3 site and the receptor grid files were generated using Grid Generation panel of Glide module.
    keywords: binding; covid-19; docking; drug; hit; interactions; molecules; protein; site; structure
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        item: #6013 of 7819
          id: cord-332795-kcvj1kmx
      author: Martín Carreras‐Presas, Carmen
       title: SARS‐CoV‐2 oral associated lesions: discussion of elicited response
        date: 2020-07-04
       words: 1484
      flesch: 47
     summary: All rights reserved syndrome in COVID-19 patients, a new scenario for an old concern: The fragile balance between infections and autoimmunity Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases Erythema multiforme-like eruption in patients with COVID-19 infection: clinical and histological findings Epidemiological, clinical and virological characteristics of 74 cases of coronavirus-infected disease 2019 (COVID-19) with gastrointestinal symptoms Strength in Diversity: Understanding the Pathways of HSV-1 reactivation Letter to the Editor: Publication of COVID-19 case reports: are we hurrying Accepted Article All rights reserved Cytokine Release Syndrome (CRS) which is seen in COVID-19 patients presents in association with immune dysregulation and tissue damages, especially at the oral and nasal mucosa.
    keywords: article; covid-19; oral
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        item: #6014 of 7819
          id: cord-332824-a2mjkz83
      author: Finnerty, Dylan T.
       title: A potential novel role for lidocaine in Covid- 19 patients?
        date: 2020-07-23
       words: 1751
      flesch: 27
     summary: The evidence that lidocaine can suppress development of netosis in perioperative patients raises the possibility of repurposing it for use in COVID-19 patients. Interestingly serum from COVID-19 patients triggered NET release from control neutrophils in vitro, suggesting COVID-19 creates a cellular environment wherein netosis is more likely to occur.
    keywords: covid-19; lidocaine; netosis; nets; neutrophil; patients
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        item: #6015 of 7819
          id: cord-332827-gll4nqdd
      author: Peixe, Paula
       title: Hepatology in the COVID Era: Another C Virus, again Challenging the Liver
        date: 2020-04-30
       words: 3993
      flesch: 48
     summary: Another concern is for patients with liver disease (either advanced or decompensated), namely, the use of drugs used off-label which have not been studied for use for the current indication or in fragile populations such as liver patients. However, COVID-19 may indeed be more severe in liver patients.
    keywords: cases; coronavirus; cov2; covid-19; disease; infection; liver; patients; risk; sars
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        item: #6016 of 7819
          id: cord-332828-a4ck2ddp
      author: Alboaneen, Dabiah
       title: Predicting the Epidemiological Outbreak of the Coronavirus Disease 2019 (COVID-19) in Saudi Arabia
        date: 2020-06-25
       words: 2894
      flesch: 53
     summary: Moreover, in [20] , they proposed a statistical model to estimate the rate of COVID-19 cases in China. In epidemiology, SIR model is belong to compartmental epidemic models.
    keywords: cases; china; covid-19; epidemic; model; number
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        item: #6017 of 7819
          id: cord-332862-2knq5vdp
      author: Barbosa, Paula Nicole Vieira Pinto
       title: Chest CT accuracy in the diagnosis of SARS-CoV-2 infection: initial experience in a cancer center
        date: 2020
       words: 2268
      flesch: 37
     summary: Acad Radiol Coronavirus disease (COVID-19): spectrum of CT findings and temporal progression of the disease Coronavirus disease 2019 (COVID-19): role of chest CT in diagnosis and management Sensitivity of chest CT for COVID-19: comparison to RT-PCR Correlation of chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 1014 Cases Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia CT manifestations of coronavirus disease-2019: a retrospective analysis of 73 cases by disease severity CT features of coronavirus disease 2019 (COVID-19) pneumonia in 62 patients in Wuhan, China Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review Temporal changes of CT findings in 90 patients with COVID-19 pneumonia: a longitudinal study Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT. Chest CT exams were reviewed by two experienced radiologists and imaging findings were classified, according to the consensus statement on reporting chest CT findings related to COVID-19 issued by the Society of Thoracic Radiology, the American College of Radiology, and the Radiology Society of North America (24) in: Typical -Multifocal ground-glass opacities with round morphology in a peripheral, posterior, and diffuse or lower lung zone distribution, with or without consolidation, visible intralobar lines (crazy paving), halo sign and reversed halo sign ( Figure 1 ).
    keywords: chest; covid-19; findings; patients
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        item: #6018 of 7819
          id: cord-332924-u6acq4mg
      author: Sibiri, Hagan
       title: Containing the impact of COVID-19: Review of Ghana's response approach
        date: 2020-11-04
       words: 2050
      flesch: 51
     summary: With the low testing capacity and general weak healthcare systems, African governments have resorted to partial or total lockdowns to limit community spread and have closed international borders to stop imported cases. 4 The rise of imported cases compelled the President to order the closure of the country's borders to human traffic effective midnight, 22 March.
    keywords: cases; covid-19; ghana; health; response
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        item: #6019 of 7819
          id: cord-332932-mq36xpai
      author: Wood, David A.
       title: Safe Reintroduction of Cardiovascular Services during the COVID-19 Pandemic: Guidance from North American Society Leadership
        date: 2020-05-04
       words: 1777
      flesch: 30
     summary: Although there will be a myriad of competing demands from multiple disciplines, this risk warrants the prioritization of cardiovascular patients as healthcare systems return to normal capacity 4 . The protection of patients and HCWs must be addressed before any reintroduction of cardiovascular procedures and tests.
    keywords: cardiovascular; covid-19; health; pandemic; patients
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        item: #6020 of 7819
          id: cord-332940-vb9ds64o
      author: Cho, Jiacai
       title: COVID‐19 infection in patients with systemic lupus erythematosus: Data from the Asia Pacific Lupus Collaboration
        date: 2020-08-25
       words: 529
      flesch: 49
     summary: In summary, we report three cases of COVID-19 infection in SLE patients from the Asia Pacific, of which one was fatal. Notably, all three patients had active SLE which required escalation of treatment just before, or during treatment for COVID-19 infection, in contrast to reports from France.
    keywords: covid-19; infection; lupus
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        item: #6021 of 7819
          id: cord-332942-l0tbak9l
      author: Kow, Chia Siang
       title: Macrolides for patients with COVID-19 and concurrent pertussis infection
        date: 2020-10-16
       words: 681
      flesch: 22
     summary: The authors [1] observed that the rate of pertussis co-infection was significantly higher in patients with COVID-19 pneumonia compared to patients with other viral pneumonia. Macrolides are the preferred antibiotic therapy for pertussis infection [2] .
    keywords: covid-19; patients
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        item: #6022 of 7819
          id: cord-332944-yqhuh3gc
      author: Wu, Jianhua
       title: Patient response, treatments and mortality for acute myocardial infarction during the COVID-19 pandemic
        date: 2020-07-30
       words: 3623
      flesch: 37
     summary: Nationwide analysis from MINAP Myocardial infarction redefined-a consensus document of the Joint European Society of Cardiology/American College of Cardiology committee for the redefinition of myocardial infarction: the Joint European Society of Cardiology/American College of Cardiology Committee Global Registry of Acute Coronary Events I. Predictors of hospital mortality in the global registry of acute coronary events National Institute for Cardiovascular Outcomes R. Patient and hospital determinants of primary percutaneous coronary intervention in England Association of onset to balloon and door to balloon time with long term clinical outcome in patients with ST elevation acute myocardial infarction having primary percutaneous coronary intervention: observational study Completeness and diagnostic validity of recording acute myocardial infarction events in primary care, hospital care, disease registry, and national mortality records: cohort study Hyperlipidaemia 12935 (30.9%, 30.5-31.3) 453 (30.5% all cells represent numbers of cases (%, 95% CI) unless otherwise stated; AMI: acute myocardial infarction IQR: interquartile range; sd: standard deviation; CABG: coronary artery bypass graft; COPD: chronic obstructive pulmonary disease; PCI: percutaneous coronary intervention Table Heart rate, beats per min, median If pre-hospital cardiac arrest: no ROSC or return but died in-hospital 532 Clopidogrel/prasugrel/ticagrelor 34280 (97.5%, 97.4-97.7) 1321 (99.2% all cells represent numbers of cases (%, 95% CI) unless otherwise stated; AMI: acute myocardial infarction ROSC: return of spontaneous circulation ACEi/ARB: The time of hospital admission was defined as the time of arrival of the ambulance at the hospital, or the accident and emergency department registration time for patients who self-presented to the department.
    keywords: ami; covid-19; decline; hospital; median; mortality; nstemi; patients; phase
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        item: #6023 of 7819
          id: cord-332967-fo12lbvs
      author: Taher, Ali T.
       title: Care of patients with hemoglobin disorders during the COVID‐19 pandemic: An overview of recommendations
        date: 2020-05-21
       words: 1369
      flesch: 41
     summary: This suggests that they may even be at higher risk compared to COVID-19 patients who do not have SCD. A series of isolated cases of ACS in SCD patients positive for COVID-19 has been recently reported.
    keywords: covid-19; infection; patients; scd
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        item: #6024 of 7819
          id: cord-332970-atwz3rgf
      author: Gentile, Pietro
       title: Adipose Stem Cells (ASCs) and Stromal Vascular Fraction (SVF) as a Potential Therapy in Combating (COVID-19)-Disease
        date: 2020-05-09
       words: 2641
      flesch: 46
     summary: Adipose tissue-derived mesenchymal stem cell yield and growth characteristics are affected by the tissue-harvesting procedure A comparative translational study: the combined use of enhanced stromal vascular fraction and platelet-rich plasma improves fat grafting maintenance in breast reconstruction Breast Reconstruction with Enhanced Stromal Vascular Fraction Fat Grafting: What Is the Best Method? Engineered Fat Graft Enhanced with Adipose-Derived Stromal Vascular Fraction Cells for Regenerative Medicine: Clinical, Histological and Instrumental Evaluation in Breast Reconstruction Concise Review: Adipose-Derived Stem Cells (ASCs) and Adipocyte-Secreted Exosomal microRNA (A-SE-miR) Modulate Cancer Growth and promote Wound Repair Leptin, adipocytes and breast cancer: Focus on inflammation and anti-tumor immunity Adipose-derived stromal vascular fraction cells and platelet-rich plasma: basic and clinical evaluation for cell-based therapies in patients with scars on the face Impact of the Different Preparation Methods to Obtain Human Adipose-Derived Stromal Vascular Fraction Cells (AD-SVFs) and Human Adipose-Derived Mesenchymal Stem Cells (AD-MSCs): Enzymatic Digestion Versus Mechanical Centrifugation Comparing mesenchymal stromal cells from different human tissues: Bone marrow, adipose tissue and umbilical cord blood Functional studies of mesenchymal stem cells derived from adult human adipose tissue Survival after mesenchymal stromal cell therapy in steroid-refractory acute graft-versus-host disease: systematic review and meta-analysis CT-04 Safety and efficacy of allogeneic umbilical cordderived mesenchymal stem cells (MSCs) in patients with systemic lupus erythematosus: results of an openlabel phase I study Application of enhanced stromal vascular fraction and fat grafting mixed with PRP in post-traumatic lower extremity ulcers Autologous stem cells (adipose) and fibrin glue used to treat widespread traumatic calvarial defects: case report Fat graft supplemented with adipose-derived stromal cells in the rehabilitation of patients with craniofacial microsomia Clinical treatment of radiotherapy tissue damage by lipoaspirate transplant: a healing process mediated by adiposederived adult stem cells Prospective trial of adipose-derived regenerative cell (ADRC)-enriched fat grafting for partial mastectomy defects: the RESTORE-2 trial Covid-19 -Navigating the uncharted A higher quantity of stem cells was observed in adipose tissue compared to bone marrow [22] .
    keywords: adipose; ascs; cells; fat; mscs; stem; tissue
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        item: #6025 of 7819
          id: cord-332979-eln7n6zb
      author: Ciminelli, G.
       title: How Emergency Care Congestion Increases Covid-19 Mortality: Evidence from Lombardy, Italy
        date: 2020-10-29
       words: 5198
      flesch: 52
     summary: How can we explain the result that Covid-19 mortality rates are higher in communities that are more distant from the intensive care? We find that Covid-19 mortality is up to 60% higher in the average municipality -- which is 15 minutes driving away from the closest ICU -- than in a municipality with an ICU in town.
    keywords: 2020; covid-19; emergency; icu; license; medrxiv; mortality; preprint
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        item: #6026 of 7819
          id: cord-332983-d28oovm2
      author: Siudak, Zbigniew
       title: Clinical and procedural characteristics of COVID‐19 patients treated with percutaneous coronary interventions
        date: 2020-07-20
       words: 1671
      flesch: 32
     summary: From ACC's Interventional Council and SCAI Reduction in ST-segment elevation cardiac catheterization laboratory activations in the United States during COVID-19 pandemic Impact of coronavirus disease 2019 (COVID-19) outbreak on ST-segment-elevation myocardial infarction care in Hong Kong Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era Decline of acute coronary syndrome admissions in Austria since the outbreak of COVID-19: the pandemic response causes cardiac collateral damage Clinical and procedural characteristics of COVID-19 patients treated with percutaneous coronary interventions The authors declare no conflict of interest. Data on patients who underwent percutaneous coronary procedures (angiography and/or percutaneous coronary intervention [PCI]) were extracted for March 13–May 13, 2020 from a national PCI database (ORPKI Registry) during the first month of national lockdown and compared with analogous time period in 2019.
    keywords: covid-19; pandemic; patients; poland
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        item: #6027 of 7819
          id: cord-332992-8rmqg4rf
      author: de Vries, A. A. F.
       title: SARS-CoV-2/COVID-19: a primer for cardiologists
        date: 2020-07-15
       words: 9215
      flesch: 31
     summary: Front Public Health Trained immunity: a tool for reducing susceptibility to and the severity of SARS-CoV-2 infection Complement as a target in COVID-19? COVID-19: immunopathology and its implications for therapy Immune-inflammatoryparameters in COVID-19 cases: a systematic review and meta-analysis AntibodyresponsestoSARS-CoV-2 in patients with COVID-19 IgA-Ab response to spike glycoprotein of SARS-CoV-2 in patients with COVID-19: a longitudinal study Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals Diagnostic testing for severe acute respiratory syndrome-related coronavirus 2: a narrative review Towards effective diagnostic assays for COVID-19: a review Coronavirus pandemic-therapy and vaccines Vaccines for SARS-CoV-2: lessons from other coronavirus strains AreviewofSARS-CoV-2 and the ongoing clinical trials Early death after feline infectious peritonitis virus challenge due to recombinant vaccinia virus immunization The challenges of vaccine development against a new virus during a pandemic The current and future state of vaccines, antivirals and gene therapies against emerging coronaviruses A systematic review of antibody mediated immunity to coronaviruses: antibody kinetics, correlates of protection, and association of antibody responses with severity of disease COVID-19: Transmission, prevention, and potential therapeutic opportunities Renin-angiotensin system inhibition in COVID-19 patients A systematic review on use of aminoquinolines for the therapeutic management of COVID-19: efficacy, safety and clinical trials The possible mechanisms of action of 4-aminoquinolines (chloroquine/hydroxychloroquine) against SARS-CoV-2 infection (COVID-19): a role for iron homeostasis? Based on previous research on SARS-CoV and MERS-CoV and various animal models of virus-induced acute lung injury as well as haematological and biochemical laboratory findings in COVID-19 patients, the following scenarios can be envisioned [33, 34, 48, 49] .
    keywords: antibody; cells; coronavirus; cov-2; covid-19; disease; human; immune; infection; injury; onset; particles; patients; protein; rna; sars; transmission; vaccines; viral; virus
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        item: #6028 of 7819
          id: cord-332995-n0zusu52
      author: Gao, Jinrui
       title: Predictive criteria of severe cases in COVID‐19 patients of early stage: A retrospective observational study
        date: 2020-09-06
       words: 2014
      flesch: 42
     summary: The imaging manifestation of severe patients and non-severe patients were different (P < .001). Through univariate logistic regression models, we found that advanced age (≥65 years old), chronic comorbidities, lymphocytopenia, elevated hs-CRP, increased D-dimer, and elevated levels of ALT were the key risk factors for the progression of COVID-19 patients into their severe stage (Table 3) .
    keywords: covid-19; data; disease; patients; risk; study
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        item: #6029 of 7819
          id: cord-333042-icgsbelo
      author: Fisher, Kiva A.
       title: Community and Close Contact Exposures Associated with COVID-19 Among Symptomatic Adults ≥18 Years in 11 Outpatient Health Care Facilities — United States, July 2020
        date: 2020-09-11
       words: 3408
      flesch: 39
     summary: key: cord-333042-icgsbelo authors: Fisher, Kiva A.; Tenforde, Mark W.; Feldstein, Leora R.; Lindsell, Christopher J.; Shapiro, Nathan I.; Files, D. Clark; Gibbs, Kevin W.; Erickson, Heidi L.; Prekker, Matthew E.; Steingrub, Jay S.; Exline, Matthew C.; Henning, Daniel J.; Wilson, Jennifer G.; Brown, Samuel M.; Peltan, Ithan D.; Rice, Todd W.; Hager, David N.; Ginde, Adit A.; Talbot, H. Keipp; Casey, Jonathan D.; Grijalva, Carlos G.; Flannery, Brendan; Patel, Manish M.; Self, Wesley H.; Hart, Kimberly W.; McClellan, Robert; Tan, Hsi-nien; Baughman, Adrienne; Hennesy, Nora A.; Grear, Brittany; Wu, Michael; Mlynarczyk, Kristin; Marzano, Luc; Plata, Zuwena; Caplan, Alexis; Olson, Samantha M.; Ogokeh, Constance E.; Smith, Emily R.; Kim, Sara S.; Griggs, Eric P.; Richards, Bridget; Robinson, Sonya; Kim, Kaylee; Kassem, Ahmed M.; Sciarratta, Courtney N.; Marcet, Paula L. title: Community and Close Contact Exposures Associated with COVID-19 Among Symptomatic Adults ≥18 Years in 11 Outpatient Health Care Facilities — United States, July 2020 date: 2020-09-11 journal: MMWR Morb Mortal Wkly Rep DOI: 10.15585/mmwr.mm6936a5 sha: doc_id: 333042 cord_uid: icgsbelo Community and close contact exposures continue to drive the coronavirus disease 2019 (COVID-19) pandemic. To assess community and close contact exposures associated with COVID-19, exposures reported by case-patients (154) were compared with exposures reported by control-participants (160).
    keywords: case; cov-2; covid-19; exposures; participants; patients; sars
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        item: #6030 of 7819
          id: cord-333083-8bxqsga2
      author: Zhou, Shuchang
       title: Imaging features and evolution on CT in 100 COVID-19 pneumonia patients in Wuhan, China
        date: 2020-05-04
       words: 3751
      flesch: 45
     summary: We compared the incidence of various CT signs in different stages of the disease, drew a CT sign change trend chart, and found that in the early rapid progressive stage, the CT imaging showed diversified primary signs including GGO plus reticular pattern, GGO plus consolidation, and GGO; consolidation The incidence of consolidation, GGO + reticular, vacuolar sign, and pleural effusion showed a trend of rising first and then falling; c repairing CT signs increasing with the course of the disease. In the advanced stage (8~14 days), GGO plus consolidation (79.8%) and repairing CT signs (subpleural line, bronchus distortion, and fibrotic strips) showed a significant increase (p < 0.05).
    keywords: consolidation; covid-19; ggo; lung; patients; stage
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        item: #6031 of 7819
          id: cord-333096-kroyaq5v
      author: Cao, Lan
       title: Ultrasound applications to support nursing care in critical ill COVID-19 patients
        date: 2020-07-15
       words: 424
      flesch: 38
     summary: The gastric residual volume should be monitored in severe COVID-19 patients with high aspiration risk every 4h, but drawing the gastric residue with a syringe presents the risk of splashing of gastric contents. There is good correlation between gastric antrum area measured by ultrasound gastric antral single-section method and gastric content volume ( The condition of severe COVID-19 patients can change quickly When the vital signs of patients change, ultrasound can be used to quickly exclude the underlying cause.
    keywords: care; patients
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        item: #6032 of 7819
          id: cord-333119-vu4qbcy1
      author: Zhang, Xiao-rui
       title: The Important Role of Volatile Components From a Traditional Chinese Medicine Dayuan-Yin Against the COVID-19 Pandemic
        date: 2020-09-25
       words: 5875
      flesch: 27
     summary: It has various pharmacological potential such as antibacterial, antiviral, and immune-enhancing properties which can be exploited in the treatment of acute upper respiratory tract infection (Zhang et al., 2013) . Furthermore, lopinavir and many interferons, especially interferon beta, have moderate effects against SARS-COV in vitro and can be used in combination with ribavirin (Chen et al., 2004; Chan et al., 2013) .
    keywords: acute; antibacterial; components; covid-19; dayuan; disease; effects; et al; injury; lung; medicine; oil; patients; prevention; treatment; yin
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        item: #6033 of 7819
          id: cord-333121-kt6t41ff
      author: Kwenandar, Felix
       title: Coronavirus Disease 2019 and Cardiovascular System: A Narrative Review
        date: 2020-06-03
       words: 1925
      flesch: 27
     summary: Thus, these patients require clinician's meticulous attention towards A novel coronavirus from patients with pneumonia in China World Health Organization Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Pathological findings of COVID-19 associated with acute respiratory distress syndrome Hematologic parameters in patients with COVID-19 infection Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) Risk Factors of Patients with Cardiac Injury and COVID-19 Acute myocardial infarction after laboratory-confirmed influenza infection Risk of myocardial infarction and stroke after acute infection or vaccination Association of coronavirus disease 2019 (covid-19) with myocardial injury and mortality Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan SARScoronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS SARS and MERS: recent insights into emerging coronaviruses Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission An Acute Respiratory Infection Runs Into the Most Common Noncommunicable Epidemic-COVID-19 and Cardiovascular Diseases SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Receptor recognition by the Novel Coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS Coronavirus The cardiovascular burden of coronavirus disease COVID-19) with a focus on congenital heart disease Coronavirus and the cardiovascular system: acute and long-term implications Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the Coronavirus Disease 2019 (COVID-19) Pandemic Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington state Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province SARS-CoV-2: a potential novel etiology of fulminant myocarditis Takotsubo cardiomyopathy triggered by Influenza A virus Overview of current lung imaging in acute respiratory distress syndrome Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Hematologic parameters in patients with COVID-19 infection Sick sinus syndrome induced by interferon and ribavirin therapy in a patient with chronic hepatitis C Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro American Society of Hematology 2018 guidelines for management of venous thromboembolism: optimal management of anticoagulation therapy The cardiovascular burden of coronavirus disease COVID-19) with a focus on congenital heart disease. Although this infective disease is mostly characterized by respiratory tract symptoms, increasing numbers of evidence had shown considerable amounts of patients with cardiovascular involvements and these were associated with higher mortality among COVID-19 patients.
    keywords: coronavirus; covid-19; disease; heart; patients; sars
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        item: #6034 of 7819
          id: cord-333131-affb4yln
      author: Jacob, Joseph
       title: Using imaging to combat a pandemic: rationale for developing the UK National COVID-19 Chest Imaging Database
        date: 2020
       words: 1668
      flesch: 33
     summary: key: cord-333131-affb4yln authors: Jacob, Joseph; Alexander, Daniel; Baillie, J. Kenneth; Berka, Rosalind; Bertolli, Ottavia; Blackwood, James; Buchan, Iain; Bloomfield, Claire; Cushnan, Dominic; Docherty, Annemarie; Edey, Anthony; Favaro, Alberto; Gleeson, Fergus; Halling-Brown, Mark; Hare, Samanjit; Jefferson, Emily; Johnstone, Annette; Kirby, Myles; Mcstay, Ruth; Nair, Arjun; Openshaw, Peter J.M.; Parker, Geoff; Reilly, Gerry; Robinson, Graham; Roditi, Giles; Rodrigues, Jonathan C.L.; Sebire, Neil; Semple, Malcolm G.; Sudlow, Catherine; Woznitza, Nick; Joshi, Indra title: Using imaging to combat a pandemic: rationale for developing the UK National COVID-19 Chest Imaging Database date: 2020 journal: Eur Respir J DOI: 10.1183/13993003.01809-2020 sha: doc_id: 333131 cord_uid: affb4yln The National COVID-19 Chest Imaging Database (NCCID) is a repository of chest X-Ray, CT and MRI images and clinical data from COVID-19 patients across the UK, to support research and development of AI technology that may proffer insights into the disease. The scale of the COVID-19 pandemic has resulted in the acquisition of huge volumes of imaging data.
    keywords: chest; covid-19; data; imaging; nccid; patients
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        item: #6035 of 7819
          id: cord-333144-gyuh2fvl
      author: Siddiqui, Arif Jamal
       title: Current status and strategic possibilities on potential use of combinational drug therapy against COVID-19 caused by SARS-CoV-2
        date: 2020-08-05
       words: 7810
      flesch: 40
     summary: This combination is already in use with phase III clinical trials underway (Andreani et al., 2020b; Gautret et al., 2020b) . Three FDA-approved broad-spectrum inhibitors (chlorpromazine, chloroquine, toremifene) that were shown to be effective against MERS-CoV infection in immortalized cell lines and evaluated their antiviral activities (Cong et al., 2018) .
    keywords: antiviral; combination; coronavirus; cov-2; covid-19; disease; drug; et al; hcq; infection; mers; patients; sars; treatment; trials; use
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        item: #6036 of 7819
          id: cord-333162-gwmvsoru
      author: Malki, Zohair
       title: Association between Weather Data and COVID-19 Pandemic Predicting Mortality Rate: Machine Learning Approaches
        date: 2020-07-17
       words: 946
      flesch: 40
     summary: For Italy, regions 33 with a temperature higher than 15 degrees Celsius and 34 75% humidity have less spread of COVID-19 cases. The researchers concluded that the 76 clustering abilities of self-organizing maps enable to 77 group countries based on COVID-19 confirmed cases.
    keywords: covid-19; spread; temperature; weather
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        item: #6037 of 7819
          id: cord-333164-1iiwhmkm
      author: Singh, Awadhesh Kumar
       title: Reply to the Letter of Mahajan and Gaur in response to the article: Comorbidities in COVID-19: outcomes in hypertensive cohort and controversies with renin angiotensin system blockers (Singh et al.)
        date: 2020-05-23
       words: 536
      flesch: 36
     summary: key: cord-333164-1iiwhmkm authors: Singh, Awadhesh Kumar; Gupta, Ritesh; Misra, Anoop title: Reply to the Letter of Mahajan and Gaur in response to the article: Comorbidities in COVID-19: outcomes in hypertensive cohort and controversies with renin angiotensin system blockers (Singh et al.) date: 2020-05-23 journal: Diabetes Metab Syndr DOI: 10.1016/j.dsx.2020.05.030 sha: doc_id: 333164 cord_uid: 1iiwhmkm nan Reply to the Letter of Mahajan and Gaur in response to the article: Comorbidities in COVID-19: outcomes in hypertensive cohort and controversies with renin angiotensin system blockers (Singh et Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Comorbidities in COVID-19: outcomes in hypertensive cohort and controversies with renin angiotensin system blockers (Singh et al.) .
    keywords: angiotensin; covid-19
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        item: #6038 of 7819
          id: cord-333175-klnxnxwm
      author: Hussein, Mohammad H.
       title: Asthma in COVID-19 patients: An extra chain fitting around the neck?
        date: 2020-11-11
       words: 2656
      flesch: 45
     summary: Univariate analysis revealed that asthma patients were more likely to be obese (75% versus 54.2%, p = 0.001), with a higher frequency of intubation (40.3% versus 27.8%, p = 0.036), and required a longer duration of hospitalization (15.1 ± 12.5 versus 11.5 ± 10.6, p = 0.015). key: cord-333175-klnxnxwm authors: Hussein, Mohammad H.; Toraih, Eman A.; Attia, Abdallah S.; Burley, Nicholas; Zhang, Allen D.; Roos, Jackson; Houghton, August; Aniemeka, Nedum; Omar, Mahmoud; Aboueisha, Mohamed; Shama, Mohamed A.; Duchesne, Juan; Kandil, Emad title: Asthma in COVID-19 patients: An extra chain fitting around the neck? date: 2020-11-11 journal:
    keywords: asthma; asthmatic; covid-19; disease; outcomes; patients
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        item: #6039 of 7819
          id: cord-333183-xyuj1j57
      author: Lee, Lennard Y W
       title: COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study
        date: 2020-05-28
       words: 4496
      flesch: 40
     summary: Mortality from COVID-19 in cancer patients appears to be principally driven by age, gender, and comorbidities. We are not able to identify evidence that cancer patients on cytotoxic chemotherapy or other anticancer treatment are at an increased risk of mortality from COVID-19 disease compared with those not on active treatment.
    keywords: anticancer; cancer; chemotherapy; covid-19; data; mortality; patients; risk; treatments
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        item: #6040 of 7819
          id: cord-333200-yka7wfbi
      author: Dhampalwar, Swapnil
       title: Treatment armamentarium of COVID-19: Evolving strategies & evidence so far
        date: 2020-07-16
       words: 1254
      flesch: 39
     summary: Patients treated with HCQ had severe disease at baseline. Convalescent plasma transfusion can be used as rescue therapy in critically ill COVID-19 pneumonia as a part of clinical trials.
    keywords: covid-19; patients; sars; treatment
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        item: #6041 of 7819
          id: cord-333225-654rd38j
      author: Chan, Khee-Siang
       title: Collateral Benefits on Other Respiratory Infections during Fighting COVID-19
        date: 2020-06-05
       words: 1532
      flesch: 33
     summary: Method: We collected week-case data of severe influenza, invasive Streptococcus pneumoniae disease and death toll from pneumonia among 25 calendar weeks of the influenza season for four years (2016-2020), which were reported to Taiwan CDC. A downturn trend of severe influenza, invasive Streptococcus pneumoniae disease and the death toll from pneumonia per week in 2019/2020 season and significant trend difference in comparison to previous seasons were noted, especially after initiation of several disease prevention measures to fight potential COVID-19 outbreak in Taiwan.
    keywords: covid-19; disease; influenza; pneumoniae; taiwan
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        item: #6042 of 7819
          id: cord-333232-jtck578z
      author: Graboyes, Evan
       title: COVID‐19 pandemic and health care disparities in head and neck cancer: Scanning the horizon
        date: 2020-06-20
       words: 2629
      flesch: 31
     summary: Although COVID-19 pandemic may eventually dissipate, health care disparities will likely persist. The COVID-19 pandemic due to SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) has disrupted and transformed the delivery of health care in ways that few would have imagined or thought possible.
    keywords: care; covid-19; disparities; health; hnc; pandemic; patients
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        item: #6043 of 7819
          id: cord-333234-yvixy77x
      author: Triposkiadis, Filippos
       title: Renin-angiotensin-system inhibition in the context of corona virus disease-19: experimental evidence, observational studies, and clinical implications
        date: 2020-09-01
       words: 3228
      flesch: 41
     summary: Searching for evidence from a new disease Risk of COVID-19 for patients with obesity Effect of angiotensinconverting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2 Effects of spironolactone and eprosartan on cardiac remodeling and angiotensin-converting enzyme isoforms in rats with experimental heart failure Interaction between RAAS inhibitors and ACE2 in the context of COVID-19 Why most published research findings are false Why randomized controlled trials are needed to accept new practices: 2 medical worldviews ACEing COVID-19: a role for angiotensin axis inhibition in SARS-CoV-2 infection? The ACE2/angiotensin-(1-7)/MAS axis of the renin-angiotensin system: focus on angiotensin Ang II (angiotensin II) conversion to angiotensin-(1-7) in the circulation is POP (prolyloligopeptidase)-dependent and ACE2 (angiotensinconverting enzyme 2)-independent Toll-like receptor 4 engagement mediates prolyl endopeptidase release from airway epithelia via exosomes The meaning of Mas ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the severe acute respiratory syndrome coronavirus spike protein Angiotensin converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system Oral delivery of angiotensin-converting enzyme 2 and angiotensin-(1-7) bioencapsulated in plant cells attenuates pulmonary hypertension Diminazene aceturate improves autonomic modulation in pulmonary hypertension Angiotensin converting enzyme 2 abrogates bleomycin-induced lung injury Recombinant angiotensin-converting enzyme 2 improves pulmonary blood flow and oxygenation in lipopolysaccharideinduced lung injury in piglets Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS Assessing ACE2 expression patterns in lung tissues in the pathogenesis of COVID-19 COVID 19 and heart failure: from infection to inflammation and angiotensin II stimulation.
    keywords: ace2; angiotensin; covid-19; enzyme; patients; raasi; sars; studies
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        item: #6044 of 7819
          id: cord-333262-xvfl7ycj
      author: Robson, B.
       title: COVID-19 Coronavirus spike protein analysis for synthetic vaccines, a peptidomimetic antagonist, and therapeutic drugs, and analysis of a proposed achilles’ heel conserved region to minimize probability of escape mutations and drug resistance
        date: 2020-04-11
       words: 21686
      flesch: 45
     summary: Not least, protein binding sites are often partially disordered before binding, and in any case there may be several binding modes. Several three dimensional structures are known for ACE2 complexed with SARS spike protein e.g. protein data bank (PDB) entry (6ACG) and of variants of the latter (e.g. TMPRSS2 protein data bank entry 2OQ5).
    keywords: ace2; acid; amino; binding; compounds; coronavirus; cov-2; data; dehydrogenase; design; e.g.; emodin; entry; human; krsfiedllfnkv; like; molecules; motif; paper; peptides; pharmacophore; present; protein; residues; sars; sequence; site; spike; studies; type; vaccine; virus
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        item: #6045 of 7819
          id: cord-333296-mvbwrb6o
      author: Nandi, Santosh
       title: Redesigning Supply Chains using Blockchain-Enabled Circular Economy and COVID-19 Experiences
        date: 2020-10-16
       words: 11148
      flesch: 33
     summary: Four ways digital works to build brands and relationships Supply chain agility: a systematic review of definitions, enablers and performance implications How Amazon is investing in a circular economy In or out: how insourcing foreign input production affects domestic production Digital technology enablers and their implications for supply chain management Trade set to plunge as Covid-19 pandemic upends global economy Closing the loop on circular economy research: from theory to practice and back again Proposing a Capability Perspective on Digital Business Models Service innovation in the digital age: key contributions and future directions COVID-19 and digital inequalities: Reciprocal impacts and mitigation strategies Complementary drivers of new product development performance: cross-functional coordination, Information System Capability, and Intelligence Quality Digital business strategy: toward a next generation of insights Additive manufacturing for consumer-centric business models: Implications for supply chains in consumer goods manufacturing The economics of the coming spaceship earth The impact of alignment between virtual enterprise and information technology on business performance in an agile manufacturing environment Agile supply chain management: where did it come from and where will it go in the era of digital transformation Blockchain tokens and the potential democratization of entrepreneurship and innovation Innovative -Bring-Service-Near-Your-Home‖ Operations under Corona-Virus (COVID-19/SARS-CoV-2) Outbreak: Can Logistics Become the Messiah? Managing disruptions and the ripple effect in digital supply chains: empirical case studies Effects of COVID-19 on business and research Re-insourcing as a manufacturing-strategic option during a crisis-cases from the automobile industry Understanding and development of supply chain agility and flexibility: a structured literature review Digital Capabilities as Driver to Digital Business Performance, Digital Commerce -eBusiness and eCommerce (SIGeBIZ) How to globalize the circular economy How to Globalize the Circular Economy Distinguishing between the concepts of supply chain agility and resilience Green marketing consumer-level theory review: A compendium of applied theories and further research directions COVID-19, the Food System and the Circular Economy: Challenges and Opportunities Policies for transitioning towards a circular economy: Expectations from the European Union (EU) key: cord-333296-mvbwrb6o authors: Nandi, Santosh; Sarkis, Joseph; Hervani, Aref Aghaei; Helms, Marilyn M. title: Redesigning Supply Chains using Blockchain-Enabled Circular Economy and COVID-19 Experiences date: 2020-10-16 journal: Sustain Prod Consum DOI: 10.1016/j.spc.2020.10.019 sha: doc_id: 333296 cord_uid: mvbwrb6o The COVID-19 pandemic has exposed businesses and societies to the shortfalls of normal patterns of production, consumption, and their long-lasting impact on supply chains.
    keywords: agility; bct; blockchain; chain; covid-19; crisis; digital; digitization; economy; et al; example; information; localization; pandemic; production; products; research; supplies; supply; supply chain; technology
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        item: #6046 of 7819
          id: cord-333326-n9ifhw5s
      author: Wardell, Hanna
       title: Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Febrile Neonates
        date: 2020-07-09
       words: 2928
      flesch: 41
     summary: Coronavirus disease 2019 in children-United States Characteristics and outcomes of children with coronavirus disease 2019 (COVID-19) infection admitted to US and Canadian pediatric intensive care units Children with Covid-19 in pediatric emergency departments in Italy Late-onset neonatal sepsis in a patient with Covid-19 SARS-CoV-2 infection (COVID-19) in febrile infants without respiratory distress Novel coronavirus in a 15-day-old neonate with clinical signs of sepsis, a case report Novel coronavirus infection in febrile infants aged 60 days and younger SARS-CoV-2 infection in infants less than 90 days old Risk of serious bacterial infection in young febrile infants with respiratory syncytial virus infections Serious bacterial infections in febrile infants 1 to 90 days old with and without viral infections Indeed, the incidence of transmission through familial exposure in pediatric COVID-19 infections has been estimated between 45% and 91% [3, 5, 7] .
    keywords: coronavirus; cov-2; covid-19; day; evaluation; infection; sars
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        item: #6047 of 7819
          id: cord-333327-r7yqk8tm
      author: Stephens, Elizabeth H.
       title: Courage, Fortitude, and Effective Leadership of Surgical Teams During COVID-19
        date: 2020-07-10
       words: 3059
      flesch: 46
     summary: Even prior to the coronavirus disease 2019 (COVID-19) pandemic, many clinicians and health care workers were experiencing burnout, as well as stress, anxiety, fatigue, and depression. One recent study based on the COVID experience in China identified that the most impactful factors associated with stress among health care workers were personal safety, concern for their families, and patient mortality.
    keywords: care; health; members; pandemic; risk; stress; work; workers
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        item: #6048 of 7819
          id: cord-333338-6mxeq8dg
      author: Cheshmehzangi, Ali
       title: COVID-19 and household energy implications: what are the main impacts on energy use?
        date: 2020-10-09
       words: 5772
      flesch: 42
     summary: key: cord-333338-6mxeq8dg authors: Cheshmehzangi, Ali title: COVID-19 and household energy implications: what are the main impacts on energy use? date: 2020-10-09 journal: Heliyon DOI: 10.1016/j.heliyon.2020.e05202 sha: doc_id: 333338 cord_uid: 6mxeq8dg This study explores the impacts of COVID-19 on household energy use. The study intends to present the results of a small pilot study conducted in China, by addressing household energy use.
    keywords: consumption; covid-19; energy; energy use; household; household energy; impacts; lockdown; pandemic; study
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        item: #6049 of 7819
          id: cord-333350-e6zak5ad
      author: Albahli, Saleh
       title: Efficient GAN-based Chest Radiographs (CXR) augmentation to diagnose coronavirus disease pneumonia
        date: 2020-06-06
       words: 3713
      flesch: 53
     summary: The experiment uses public dataset shared by 2019@Kaggle:Digital pathology classification challenge, 2019, and the Covid-19 images from the paper: Joseph Paul Cohen and Paul Morrison and Lan Dao, COVID-19 image data collection, arXiv: 2003.11597, 2020 (https://github.com/ieee8023/ covid-chestxray-dataset). Augmentation was also applied in order to cover wide range of X-ray images that may come across the model in field.
    keywords: accuracy; chest; classes; covid-19; data; images; model
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        item: #6050 of 7819
          id: cord-333368-kjrk8nn9
      author: Huizinga, Gabrielle P
       title: The Collision of Meta-Inflammation and SARS-CoV-2 Pandemic Infection
        date: 2020-09-03
       words: 5494
      flesch: 33
     summary: Obesity has been shown to be a risk factor for human papilloma virus incident infection, however obesity was not associated with how long the infection persisted 79 . A meta-analysis The role of increased body mass index in outcomes of sepsis: a systematic review and meta-analysis Body Habitus and Risk of Mortality in Pediatric Sepsis and Septic Shock: A Retrospective Cohort Study Outcomes and Resource Use Among Overweight and Obese Children With Sepsis in the Pediatric Intensive Care Unit Influence of Obesity Diagnosis With Organ Dysfunction, Mortality, and Resource Use Among Children Hospitalized With Infection in the United States The Role of Obesity in Sepsis Outcome among Critically Ill Patients: A Retrospective Cohort Analysis Underweight, overweight, and obesity as independent risk factors for hospitalization in adults and children from influenza and other respiratory viruses Increased risk of influenza among vaccinated adults who are obese Impact of obesity on sepsis mortality:
    keywords: covid-19; disease; infection; inflammation; macrophages; obesity; patients; risk; sars
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        item: #6051 of 7819
          id: cord-333411-hqtb4a2c
      author: Tan, Tina Q
       title: Location Matters: Geographic Disparities and Impact of Coronavirus Disease 2019 (COVID-19)
        date: 2020-09-17
       words: 1770
      flesch: 42
     summary: M a n u s c r i p t COVID-19 and the unequal surge in mortality rates in Code measures of poverty, household crowding, race/ethnicity, and racialized economic segregation Racial disparities emerge in Tennessee's testing for COVID-19 Data on COVID-19 cases in Unhealthier states have lower COVID-19 testing rates Rural America could be the region hardest hit by the COVID-19 outbreak Geographic access to United States SARS-CoV-2 testing sites highlights healthcare disparities and may bias transmission estimates Characteristics and outcomes of children with coronavirus disease 2019 (COVID-19) infection admitted to US and Canadian pediatric intensive care units Hyperinflammatory shock in children during COVID-19 pandemic. A recent analysis highlighted that geographic access to COVID-19 testing sites is as uneven as access to overall health care, with higher travel times to COVID-19 test sites in rural counties and in counties with a larger non-white or uninsured population, suggesting that COVID-19 cases are potentially under-counted and under-reported in these areas.
    keywords: access; areas; covid-19; states; testing
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        item: #6052 of 7819
          id: cord-333417-edc509xr
      author: Bontempi, Elza
       title: Commercial exchanges instead of air pollution as possible origin of COVID-19 initial diffusion phase in Italy: more efforts are necessary to address interdisciplinary research
        date: 2020-06-13
       words: 1613
      flesch: 24
     summary: First data analysis about possible COVID-19 virus airborne diffusion due to 220 air particulate matter (PM): the case of Lombardy (Italy) Environmental Research (2020) 221 186, 109639 Understanding COVID-19 diffusion requires an 224 interdisciplinary, multi-dimensional approach PM10 exposure is associated 228 with increased hospitalizations for respiratory syncytial virus bronchiolitis among infants in 229 Factors determining the diffusion of COVID-19 and suggested strategy to 233 prevent future accelerated viral infectivity similar to COVID Regional air pollution persistence links to 237 covid19 infection zoning The Pollution Particulate 241 A platform to investigate the effects of particulate air pollutants on 242 viral infectivity Cardiovascular effects of airborne particulate matter: A review of 246 rodent model studies Contribution of bioaerosols to airborne particulate matter Airborne transmission of SARS-CoV-2: The world should face the 254 reality Seasonal 256 variations in the chemical composition of particulate matter: a case study in the Po Valley Part Concerning COVID-19 diffusion in the air, some recent published papers support the idea 44 that the airborne transmission is a mechanism of virus diffusion.
    keywords: covid-19; diffusion; transmission; virus
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        item: #6053 of 7819
          id: cord-333451-p2plpeew
      author: Raab, Anja M.
       title: Significant demands on healthcare resources during the COVID crisis
        date: 2020-05-13
       words: 957
      flesch: 46
     summary: Positioning and mobilization are effective methods of respiratory therapy. There are various methods and devices for respiratory therapy with different objectives.
    keywords: care; covid-19; patients; respiratory
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        item: #6054 of 7819
          id: cord-333460-4ui8i9u5
      author: Li, Qing
       title: The Psychological Health Status of Healthcare Workers During the COVID-19 Outbreak: A Cross-Sectional Survey Study in Guangdong, China
        date: 2020-09-18
       words: 3589
      flesch: 51
     summary: HCW respondents had feelings of social discrimination. Contact with COVID-19 cases or suspected cases, worry about suffering from COVID-19, worry about their family, and dismission during the COVID-19 period were significant work-related contributing factors to the psychological health problems of HCW (all p<0.01).
    keywords: anxiety; covid-19; depression; hcw; health; risk; study
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        item: #6055 of 7819
          id: cord-333462-h6czvcyq
      author: None
       title: COVID-19 olfactory screening test using trained dogs
        date: 2020-09-15
       words: 725
      flesch: 40
     summary: The idea of using dog olfactory tests to detect patients suffering from COVID-19 has been considered by multidisciplinary teams (veterinarians, physicians, biologists, dog handlers) to meet the worldwide demand for a rapid, simple, non-invasive, sensitive and specific screening test that can reduce the workload of medical biology laboratories. Indeed, in view of the increasing demand for COVID-19 detection tests, the use of 'sniffer dogs' would reduce the still excessively long delays in obtaining RT-PCR screening, especially for suspicious cases and contacts [2] .
    keywords: covid-19; detection; dogs
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        item: #6056 of 7819
          id: cord-333470-0a0i6vjn
      author: Lombe, Dorothy C
       title: Zambia’s National Cancer Centre response to the COVID-19 pandemic—an opportunity for improved care
        date: 2020-05-28
       words: 3350
      flesch: 44
     summary: This COVID-19 crisis is being seen as an opportunity to develop a robust referral system so that cancer patients do not have to wait for treatment in Lusaka or travel to and fro across the country but instead arrive for scheduled visits. The adjustment of workflows due to the epidemic has seen positive shifts in some aspects of service delivery for cancer patients in this low middle-income country ( Figure 1 ).
    keywords: cancer; care; cases; centre; covid-19; health; pandemic; patients; staff; treatment
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        item: #6057 of 7819
          id: cord-333475-pe7q9ira
      author: Vargas-Vargas, Manuel
       title: Ferritin levels and COVID-19
        date: 2020-06-01
       words: 695
      flesch: 37
     summary: The First Autopsy Series from New Orleans The potential role of IL-6 in monitoring severe case of coronavirus disease 2019 COVID-19: consider cytokine storm syndromes and immunosuppression A Review on Iron Chelators in Treatment of Iron Overload Syndromes Dietary factors associated with high serum ferritin levels in postmenopausal women with the Fifth Korea National Health and Nutrition Examination Survey (KNHANES V) Dietary factors associated with the risk of high iron stores in the elderly Framingham Heart Study cohort On this basis, we briefly review evidence supporting the hypothesis that ferritin levels might be a crucial factor influencing the severity of COVID-19.
    keywords: covid-19; ferritin; levels
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        item: #6058 of 7819
          id: cord-333483-nr0akd7k
      author: Aziz, R.
       title: Essential notes: The use of Lung Ultrasound for COVID-19 in the intensive care unit
        date: 2020-09-26
       words: 1115
      flesch: 50
     summary: Guidance for lung ultrasound during COVID-19 Practical approach to lung ultrasound Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review Findings of lung ultrasonography of novel corona virus pneumonia during the 2019-2020 epidemic Lung Ultrasound in the Critically Ill Sonographic signs and patterns of COVID-19 pneumonia Lung ultrasonography in pulmonary The 'light-beam artefact' that has also been described may be a confluence of C lines leading to a different appearance than that seen in pulmonary oedema or bacterial pneumonia.
    keywords: covid-19; lines; lung; ultrasound
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        item: #6059 of 7819
          id: cord-333487-zem2d4y6
      author: Thomaz Ugliara Barone, Mark
       title: The Impact of COVID-19 on People with Diabetes in Brazil
        date: 2020-07-03
       words: 4659
      flesch: 41
     summary: The Lancet The Silver Lining to COVID-19: Avoiding Diabetic Ketoacidosis Admissions with Telehealth Coronavirus Infections and Type 2 Diabetes -Shared Pathways with Therapeutic Implications Ensuring people-centred diabetes care during the COVID-19 pandemic Experiences from Portugal Beyond the virus: Additionally, announced measures for prevention and mitigation of COVID-19 consequences on this population, such as supply of medicines for 3 months, worked just for a minority.
    keywords: blood; brazil; care; covid-19; diabetes; glucose; health; individuals; measures; pandemic; people
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        item: #6060 of 7819
          id: cord-333520-v2sb90rc
      author: Gardin, Chiara
       title: Could Mesenchymal Stem Cell-Derived Exosomes Be a Therapeutic Option for Critically Ill COVID-19 Patients?
        date: 2020-08-26
       words: 10167
      flesch: 29
     summary: Several studies agree that reduced fibrosis and apoptosis of myocardial cells are other important effects of the EV-mediated ischemic cardiac repair Evidence from meta-analysis Cardiovascular disease and COVID-19 Clinical Characteristics of 138 Hospitalized Patients with 2019 Novel Coronavirus-Infected Pneumonia in Inside the heart of COVID-19 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study Clinical Characteristics of Coronavirus Disease 2019 in China COVID-19 and the cardiovascular system Mesenchymal stem cells and management of COVID-19 pneumonia Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury On the use of corticosteroids for 2019-nCoV pneumonia Coronaviruses and the cardiovascular system: Acute and long-term implications Treatment for emerging viruses: Convalescent plasma and COVID-19 Recommendations for Investigational COVID-19 Convalescent Plasma Chinese Clinical Trial Registry Coronavirus Disease 2019 (COVID-19) and Cardiovascular Disease: A Viewpoint on the Potential Influence of Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers on Onset and Severity of Severe Acute Respiratory Syndrome Coronavirus 2 Infection Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus.
    keywords: acute; cardiac; cells; covid-19; disease; effects; evs; exosomes; human; inflammatory; injury; lung; mesenchymal; msc; mscs; mvs; patients; sars; stem
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        item: #6061 of 7819
          id: cord-333528-9mczqtje
      author: Mattogno, P. P.
       title: Transnasal endoscopic skull base surgery during COVID-19 pandemic: algorithm of management in an Italian reference COVID center
        date: 2020-06-03
       words: 1076
      flesch: 40
     summary: In patients requiring urgent surgery, we adopted our Institutional protocol for surgical emergencies in COVID+ patients. Encouraging and implementing strict protection measures to providers and patients will prevent the further spreading of the COVID-19 infection in hospital settings where the care to selected patient requiring urgent surgery must continue.
    keywords: covid-19; endoscopic; patients; surgery
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        item: #6062 of 7819
          id: cord-333581-icp0xwhx
      author: Aziz, Muhammad
       title: Gastrointestinal predictors of severe COVID-19: systematic review and meta-analysis
        date: 2020-07-30
       words: 4314
      flesch: 38
     summary: Given the association of diarrhea with severe COVID-19 disease, based on our meta-analysis results, COVID-19 patients with diarrhea should be stratified into a high-risk group for developing severe disease as described above and managed accordingly. Articles were selected if they reported data on COVID-19 patients with respect to gastrointestinal symptoms (diarrhea, abdominal pain, and nausea/vomiting) or laboratory findings (serum AST, ALT, or TB).
    keywords: analysis; characteristics; clinical; coronavirus; covid-19; disease; patients; studies; study
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        item: #6063 of 7819
          id: cord-333582-l2coget2
      author: Giacomelli, A.
       title: 30-day mortality in patients hospitalized with COVID-19 during the first wave of the Italian epidemic: a prospective cohort study
        date: 2020-05-06
       words: 3048
      flesch: 57
     summary: Methods: This prospective cohort study of the correlates of the risk of death in COVID-19 patients was conducted at the Infectious Diseases and Intensive Care units of Luigi Sacco Hospital, Milan, Italy. The large structural changes that had to be made in the organisation of our hospital over a 2-week period transformed our 68-bed Department of Infectious Diseases and 8-bed general intensive care unit (ICU) into a singlebuilding isolation area with 93 non-intensive and 30 intensive care beds entirely dedicated to COVID-19 patients.
    keywords: admission; author; covid-19; medrxiv; patients; preprint; study
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        item: #6064 of 7819
          id: cord-333627-tcgamaev
      author: Kam, Ariana
       title: PERCEIVED STRESS, INSOMNIA SEVERITY, AND THE IMPACT OF EVENTS AMONG IN VITRO FERTILIZATION (IVF) PATIENTS DURING THE CORONAVIRUS DISEASE 2019 (COVID-19) PANDEMIC
        date: 2020-09-30
       words: 2113
      flesch: 47
     summary: There was no statistically significant relationship between the demographic variables of not surpassing a high school education and being unemployed and the perceived stress levels of IVF patients during the COVID-19 pandemic. key: cord-333627-tcgamaev authors: Kam, Ariana; Gottfried, Jennifer; Mieleszko, Julia E.; Kim, You J.; Nejat, Edward J.; Luk, Janelle title: PERCEIVED STRESS, INSOMNIA SEVERITY, AND THE IMPACT OF EVENTS AMONG IN VITRO FERTILIZATION (IVF) PATIENTS DURING THE CORONAVIRUS DISEASE 2019 (COVID-19) PANDEMIC date: 2020-09-30 journal: Fertility and Sterility DOI: 10.1016/j.fertnstert.2020.08.500 sha: doc_id:
    keywords: covid-19; pandemic; patients; providers; respondents; stress
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        item: #6065 of 7819
          id: cord-333631-vk3h2qau
      author: Tsoungui Obama, H. C. J.
       title: Preventing COVID-19 spread in closed facilities by regular testing of employees - an efficient intervention in long-term care facilities and prisons
        date: 2020-10-14
       words: 4482
      flesch: 51
     summary: We study the impact of testing employees in LTCFs or incarceration facilities to protect 68 immobile risk groups from COVID-19 infections using an extended SEIR model, i.e., by 69 a deterministic compartmental model of ordinary differential equations. Coronavirus disease 2019 (COVID-19) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges Clinical features of patients infected with 2019 novel coronavirus in Wuhan The possible immunological pathways for the variable immunopathogenesis of COVID-19 infections among healthy adults, elderly and children A systematic review of asymptomatic infections with COVID-19 Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship African journal of primary health care & family medicine Hyperbaric Oxygen Therapy in Non-ventilated COVID-19
    keywords: covid-19; employees; individuals; preprint; risk; table; testing; tests
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        item: #6066 of 7819
          id: cord-333640-oh9ucair
      author: Gambaro, Giovanni
       title: Nothing will ever be as before. Reflections on the COVID-19 epidemics by nephrologists in eleven countries
        date: 2020-05-25
       words: 2796
      flesch: 64
     summary: I am surprised when I get to an area where many patients are treated, and where there were many sounds, and many familiar noises. And from Russia: when the COVID-19 pandemic reached Moscow, my hospital was not dedicated to COVID-19 patients, later on a special unit was selected for suspected cases, and last week we opened a COVID-19 center (2 buildings).
    keywords: colleagues; covid-19; fear; hospital; patients; work
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        item: #6067 of 7819
          id: cord-333654-8rg99di5
      author: Pillai, Presaad
       title: COVID-19 AND MAJOR ORGAN THROMBOEMBOLISM: MANIFESTATIONS IN NEUROVASCULAR AND CARDIOVASCULAR SYSTEMS.
        date: 2020-10-24
       words: 4130
      flesch: 30
     summary: A novel hypothesis for clinically suspected hypercoagulopathy and microvascular immunothrombosis Procoagulant activity during viral infections Targeting the cytokine storm for therapeutic benefit Modulating the Innate Immune Response to Influenza A Virus: Potential Therapeutic Use of Anti-Inflammatory Drugs Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Pandemic H1N1 Influenza Infection and Vascular Thrombosis PAMPs and DAMPs as triggers for DIC Disseminated intravascular coagulation Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia COVID-19 coagulopathy: an indepth analysis of the coagulation system D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19 Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past A major outbreak of severe acute respiratory syndrome in Hong Kong Acute Pulmonary Embolism Associated with COVID-19 Pneumonia Detected with Pulmonary CT Angiography The clinical pathology of severe acute respiratory syndrome (SARS): a report from China Immunohistochemical, and Ultrastructural Findings of a Fatal Case of Middle East Respiratory Syndrome Coronavirus Infection in the United Arab Emirates Histopathologic Changes and SARS-CoV-2 Immunostaining in the Lung of a Patient With COVID-19 Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans Postmortem examination of COVID-19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Extremely High Incidence of Lower Extremity Deep Venous Thrombosis in 48 Patients With Severe COVID-19 in Wuhan Incidence and associated factors of deep vein thrombosis in Thai surgical ICU patients without chemoprophylaxis: one year study Deep Vein Thrombosis among Intensive Care Unit Patients Empirical systemic anticoagulation is associated with decreased venous thromboembolism in critically ill influenza A H1N1 acute respiratory distress syndrome patients Acute cerebrovascular disease following COVID-19: a single center, retrospective, observational study COVID-19-associated Acute Hemorrhagic Necrotizing Encephalopathy: Characteristics of ischaemic stroke associated with COVID-19 COVID-19 and the cardiovascular system Acute myocarditis associated with novel Middle east respiratory syndrome coronavirus Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Cardiovascular manifestations and treatment considerations in COVID-19 Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Risk of peripheral arterial thrombosis in COVID-19 Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19) ST-Elevation Myocardial Infarction in Patients With COVID-19:
    keywords: coronavirus; covid-19; dimer; disease; patients; pulmonary; sars; thromboembolism; thrombosis
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        item: #6068 of 7819
          id: cord-333663-0yzrcfe5
      author: Hart, Joanna L.
       title: Family-Centered Care During the COVID-19 Era
        date: 2020-04-22
       words: 1597
      flesch: 40
     summary: Health systems must severely restricting or eliminating family presence for all patients, to protect the health of patients, family members, and workers. 5 Restrictions on family presence should not undermine adherence to the principles of familycentered care.
    keywords: care; covid-19; family; patients; presence
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        item: #6069 of 7819
          id: cord-333670-qv1orlv5
      author: Mutti, Luciano
       title: Coronavirus Disease (Covid-19): What Are We Learning in a Country With High Mortality Rate?
        date: 2020-05-28
       words: 2505
      flesch: 30
     summary: Interestingly, another preprint study identified specific SARS-COV-2 neutralizing antibodies (NAbs) in the plasma of patients who had recovered from infection and recorded that 30% of patients failed to develop high titers of NAbs after COVID-19 infection (32) . In Italy, the possibility of performing autopsies or post-mortem diagnostic studies on suspect, probable, or confirmed COVID-19 cases has been intensively debated (5, 6) ; however, postmortem pathological analysis of COVID-19 patients in China has shown findings consistent with Acute Respiratory Distress Syndrome (ARDS) (7-9) (Figure 1 ).
    keywords: cov-2; covid-19; hla; patients; response; sars; virus
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        item: #6070 of 7819
          id: cord-333696-3ci9re9a
      author: Alomari, Safwan O.
       title: COVID-19 and the Central Nervous System
        date: 2020-08-04
       words: 4426
      flesch: 40
     summary: We believe that this association between smoking and COVID-19 neurological manifestations, if proven, might be of great impact, since all the people worldwide are currently at high risk of being exposed to smoking and COVID-19 infection. Patients with COVID-19 infection should be evaluated early for neurological symptoms.
    keywords: acute; brain; case; coronavirus; cov-2; covid-19; disease; encephalitis; infection; patients; sars
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        item: #6071 of 7819
          id: cord-333698-e73d9lbu
      author: Lechien, Jerome R.
       title: Features of Mild-to-Moderate COVID-19 Patients with Dysphonia.
        date: 2020-06-04
       words: 1774
      flesch: 47
     summary: The prevalence of the following symptoms was higher in dysphonic patients compared with non-dysphonic patients: cough, chest pain, sticky sputum, arthralgia, diarrhea, headache, fatigue, nausea and vomiting. To explore the prevalence of dysphonia in European patients with mild-to-moderate COVID-19 and the clinical features of dysphonic patients.
    keywords: covid-19; dysphonia; group; pain; patients; symptoms
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        item: #6072 of 7819
          id: cord-333703-1ku3jc9s
      author: Kraus, Aurora
       title: A zebrafish model for COVID-19 recapitulates olfactory and cardiovascular pathophysiologies caused by SARS-CoV-2
        date: 2020-11-08
       words: 8459
      flesch: 39
     summary: 521 Interestingly, we did not observe any changes in ace2 expression after 3h immersion with SARS-522 CoV-2 S RBD protein. 300 There are copious amounts of immune cells in the teleost olfactory organ ( Intranasal delivery of SARS-CoV-2 S RBD induces inflammatory responses and 318 widespread loss of olfactory receptor expression in adult zebrafish olfactory organ 319 320 The cellular landscape of the zebrafish olfactory epithelium was affected by SARS-CoV-2 S 321 RBD treatment and time ( Figure 4A -D).
    keywords: ace2; cell; cov-2; covid-19; et al; expression; figure; gene; infection; larvae; olfactory; protein; rbd; responses; s rbd; sars; treatment; type; zebrafish
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        item: #6073 of 7819
          id: cord-333713-nz36i2oa
      author: Andonegui-Elguera, Sergio
       title: Molecular Alterations Prompted by SARS-CoV-2 Infection: Induction of Hyaluronan, Glycosaminoglycan and Mucopolysaccharide Metabolism
        date: 2020-06-18
       words: 1730
      flesch: 25
     summary: Several inflammatory cytokines produced in COVID-19 could be strong inducers of hyaluronan metabolism (10) therefore the relevance to identify immune cells infiltrating lung tissue. Aim of the study In the present work we performed a stringent metanalysis from the publicly available RNAseq data from bronchoalveolar cells and peripheral blood mononuclear cells to elucidate molecular alterations and cellular deconvolution to identify immune cell profiles.
    keywords: cells; covid-19; hyaluronan; infection; patients; sars
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        item: #6074 of 7819
          id: cord-333745-nwnt2tde
      author: Wang, Yi
       title: Clinical characteristics and laboratory indicator analysis of 67 COVID-19 pneumonia patients in Suzhou, China
        date: 2020-10-12
       words: 4400
      flesch: 45
     summary: Laboratory data showed that the WBC, N%, and CRP in Group B COVID-19 pneumonia patients were significantly higher than those of Group A patients, and the differences were statistically significant (P < 0.05). Therefore, the findings of statistical tests and p values should be interpreted with caution, and it is important to note that nonsignificant p values do not necessarily rule out the difference between Group A and Group B patients.
    keywords: coronavirus; covid-19; fib; group; group b; patients; pneumonia
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        item: #6075 of 7819
          id: cord-333749-45v6b4tc
      author: Xie, Guogang
       title: The role of peripheral blood eosinophil counts in COVID‐19 patients
        date: 2020-06-20
       words: 4006
      flesch: 51
     summary: Fatigue was more common in COVID-19 patients, suspected patients and influenza pneumonia patients than other types of pneumonia patients (66.7%, 58.3%, 66.7% vs 39.8%). All rights reserved severe patients and 9 severe patients had been discharged, while three severe patients had received mechanical ventilation and one of them had died finally.
    keywords: article; blood; copyright; counts; covid-19; eos; patients; pneumonia
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        item: #6076 of 7819
          id: cord-333792-h4f125hr
      author: Islamoglu, Yuce
       title: Objective evaluation of the nasal mucosal secretion in COVID-19 patients with anosmia
        date: 2020-10-19
       words: 1645
      flesch: 58
     summary: To evaluate nasal mucosal secretion objectively in COVID-19 patients with anosmia. key: cord-333792-h4f125hr authors: Islamoglu, Yuce; Gemcioglu, Emin; Ates, Ihsan title: Objective evaluation of the nasal mucosal secretion in COVID-19 patients with anosmia date: 2020-10-19 journal:
    keywords: covid-19; dysfunction; nasal; patients
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        item: #6077 of 7819
          id: cord-333793-4pvjc4un
      author: Dickens, Borame L
       title: Strategies at points of entry to reduce importation risk of COVID-19 cases and re-open travel
        date: 2020-08-25
       words: 1538
      flesch: 19
     summary: METHODS: To estimate active case exportation risk from 153 countries with recorded COVID-19 cases and deaths, we created a simple data-driven framework to calculate the number of infectious and upcoming infectious individuals out of 100 000 000 potential travellers from each country, and assessed six importation risk reduction strategies; Strategy 1 (S1) has no screening on entry, S2 tests all travellers and isolates test positives where those who test negative at 7 days are permitted entry, S3 the equivalent but for a 14 day period, S4 quarantines all travellers for 7 days where all are subsequently permitted entry, S5 the equivalent for 14 days and S6 the testing of all travellers and prevention of entry for those who test positive. To estimate active case exportation risk from 153 countries with recorded COVID-19 cases and deaths, we created a simple data-driven framework to calculate the number of infectious and upcoming infectious individuals out of 100 000 000 potential travellers from each country, and assessed six importation risk reduction strategies; Strategy 1 (S1) has no screening on entry, S2 tests all travellers and isolates test positives where those who test negative at 7 days are permitted entry, S3 the equivalent but for a 14 day period, S4 quarantines all travellers for 7 days where all are subsequently permitted entry, S5 the equivalent for 14 days and S6 the testing of all travellers and prevention of entry for those who test positive.
    keywords: covid-19; days; entry; test; travellers
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        item: #6078 of 7819
          id: cord-333797-six8wzxz
      author: Heaney, Ashley I.
       title: Newly diagnosed diabetes and diabetic ketoacidosis precipitated by COVID-19 infection
        date: 2020-06-06
       words: 902
      flesch: 58
     summary: COVID-19 infection may cause ketosis and ketoacidosis Practical recommendations for the management of diabetes in patients with COVID-19 Diabetic ketoacidosis precipitated by Covid-19 in a patient with newly diagnosed diabetes mellitus Endocrine and metabolic link to coronavirus infection Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19 Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes Angiotensin II and the endocrine pancreas: effects on islet blood flow and insulin secretion in rats As emergency physicians continue to treat patients with COVID-19 infection, it is important to understand the implications this disease can have on organ systems.
    keywords: covid-19; diabetes; patient
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        item: #6079 of 7819
          id: cord-333800-qqe331ok
      author: Whyte, Martin B.
       title: Pulmonary embolism in hospitalised patients with COVID-19
        date: 2020-07-10
       words: 2692
      flesch: 49
     summary: Evolution of D-dimer values may occur during illness, and evaluation of serial measurement would be of interest in COVID-19 patients. [12] highlighted that the majority of COVID-19 patients who died during hospital stay, fulfilled the criteria for disseminated intravascular coagulation (71.6 vs. 0.6% in survivors) although overall numbers were low (15 of 21 non-survivors, total cohort n= 182).
    keywords: covid-19; dimer; patients; pulmonary; score; wells
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        item: #6080 of 7819
          id: cord-333805-xmqs2ax7
      author: Romoli, Michele
       title: A systematic review of neurological manifestations of SARS‐CoV‐2 infection: the devil is hidden in the details
        date: 2020-06-05
       words: 4032
      flesch: 41
     summary: They found that COVID-19 patients were significantly younger (81%) and a high rate of smell (45%) and taste disorders (90.%). A multicentre retrospective study evaluated the occurrence of seizures in COVID-19 patients [19] .
    keywords: case; covid-19; csf; disease; infection; patients; pcr; sars; study
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        item: #6081 of 7819
          id: cord-333827-zpdnzwle
      author: Zhao, Jinqiu
       title: Potential risk factors for case fatality rate of novel coronavirus (COVID-19) in China: A pooled analysis of individual patient data
        date: 2020-08-17
       words: 2791
      flesch: 51
     summary: The following inclusive selection criteria were applied: (i) patients were diagnosed with 2019 novel coronavirus diseases (COVID-19) (ii) study design was the J o u r n a l P r e -p r o o f Journal Pre-proof cohort study comparing fatal patients with non-fatal patients (or severe cases versus non-severe cases). In contrast, the proportion of men and women showed no statistical difference between ICU patients and non-ICU patients in another study [18] .
    keywords: analysis; cfr; coronavirus; covid-19; patients; study
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        item: #6082 of 7819
          id: cord-333863-mtljy3s6
      author: Hong, Nan
       title: Evaluation of ocular symptoms and tropism of SARS‐CoV‐2 in patients confirmed with COVID‐19
        date: 2020-04-26
       words: 4039
      flesch: 47
     summary: key: cord-333863-mtljy3s6 authors: Hong, Nan; Yu, Wangshu; Xia, Jianhua; Shen, Ye; Yap, Maurice; Han, Wei title: Evaluation of ocular symptoms and tropism of SARS‐CoV‐2 in patients confirmed with COVID‐19 date: 2020-04-26 journal: We evaluated ocular symptoms and ocular tropism of SARS‐CoV‐2 in a group of patients with COVID‐19.
    keywords: covid-19; eye; onset; patients; subjects; surface; symptoms
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        item: #6083 of 7819
          id: cord-333872-shhugvx0
      author: Kumar, Jitendra
       title: The conundrum of rising Covid19 infection among health care workers: An emerging paradigm
        date: 2020-07-04
       words: 576
      flesch: 56
     summary: key: cord-333872-shhugvx0 authors: Kumar, Jitendra; Khatana, P.S.; Raina, Rajni title: The conundrum of rising Covid19 infection among health care workers: An emerging paradigm date: 2020-07-04 journal: Am J Emerg Med DOI: 10.1016/j.ajem.2020.07.001 sha: doc_id: 333872 cord_uid: shhugvx0 nan in your esteemed journal has drawn our attention and we read it very keenly. COVID-19 in health care workers -A systematic review and meta-analysis The use of personal protective equipment in the COVID-19 pandemic era COVID-19 and the Risk to Health Care Workers: A Case Report Death from Covid-19 of 23 Health Care Workers in China COVID-2019)
    keywords: hcws; infection
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        item: #6084 of 7819
          id: cord-333897-isodrtly
      author: Shenoy, Niraj
       title: Considerations for target oxygen saturation in COVID-19 patients: are we under-shooting?
        date: 2020-08-19
       words: 2843
      flesch: 30
     summary: key: cord-333897-isodrtly authors: Shenoy, Niraj; Luchtel, Rebecca; Gulani, Perminder title: Considerations for target oxygen saturation in COVID-19 patients: are we under-shooting? date: 2020-08-19 journal: BMC Med DOI: 10.1186/s12916-020-01735-2 sha: doc_id: 333897 cord_uid: isodrtly BACKGROUND: The current target oxygen saturation range for patients with COVID-19 recommended by the National Institutes of Health is 92–96%. Finally, it discusses potential implications of specific clinical observations and considerations in COVID-19 patients on target oxygen saturation, such as diffuse systemic endothelitis and microthrombi playing an important pathogenic role in the wide range of systemic manifestations, exacerbation of hypoxic pulmonary vasoconstriction in the setting of pulmonary vascular endothelitis/microthrombi, the phenomenon of “silent hypoxemia” with some patients presenting to the hospital with severe hypoxemia disproportional to symptoms, and overburdened health systems and public health resources in many parts of the world with adverse implications on outpatient monitoring and early institution of oxygen supplementation.
    keywords: ace2; covid-19; expression; oxygen; patients; saturation; target
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        item: #6085 of 7819
          id: cord-333925-5qg4mufh
      author: Martino, M.
       title: Impact of COVID-19 pandemic on psychophysical stress in patients with adrenal insufficiency: the CORTI-COVID study
        date: 2020-09-18
       words: 4597
      flesch: 43
     summary: However, secondary AI patients were more worried about the economic impact of the pandemic, whereas primary AI patients feared for their personal health most (ρ = 0.854 and 0.888, respectively; p < 0.0001). Patients with primary AI showed a gender difference in the chosen hashtag (#5 for males, #1 and #3 for females, p = 0.023); moreover, patients with primary AI who continued to work without restrictive measures chose #1, while #3 and #5 were preferred by primary AI patients under working restrictions (p = 0.024).
    keywords: covid-19; health; patients; primary
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        item: #6086 of 7819
          id: cord-333928-boq65pci
      author: Lee, Jia‐Jung
       title: Review of the present features and the infection control challenges of COVID‐19 pandemic in dialysis facilities
        date: 2020-06-03
       words: 1729
      flesch: 42
     summary: Accordingly, this interim summary is not a comprehensive review but aims to update present clinical information and infection control strategies currently focusing on COVID-19 control in dialysis facilities. The first two mortality cases in the United States were ESRD cases under regular hemodialysis (HD).
    keywords: cases; covid-19; dialysis; disease; infection; patients
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        item: #6087 of 7819
          id: cord-333932-aqcllik0
      author: Diao, Bo
       title: Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19)
        date: 2020-05-01
       words: 3829
      flesch: 42
     summary: T cells play a critical role in antiviral immunity but their numbers and functional state in COVID-19 patients remain largely unclear. Methods: We retrospectively reviewed the counts of T cells and serum cytokine concentration from data of 522 patients with laboratory-confirmed COVID-19 and 40 healthy controls.
    keywords: cd4; cd8; cells; covid-19; icu; patients; t cells
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        item: #6088 of 7819
          id: cord-333943-9d93na7s
      author: Jeong, Han Eol
       title: Association between NSAIDs use and adverse clinical outcomes among adults hospitalized with COVID-19 in South Korea: A nationwide study
        date: 2020-07-27
       words: 3390
      flesch: 37
     summary: key: cord-333943-9d93na7s authors: Jeong, Han Eol; Lee, Hyesung; Shin, Hyun Joon; Choe, Young June; Filion, Kristian B; Shin, Ju-Young title: Association between NSAIDs use and adverse clinical outcomes among adults hospitalized with COVID-19 in South Korea: Compared with non-use, NSAIDs use was associated with increased risks of the primary composite outcome (OR 1.54
    keywords: covid-19; non; nsaids; use; users
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        item: #6089 of 7819
          id: cord-333960-pkpbts7s
      author: Genet, Bastien
       title: COVID-19 in-hospital mortality and use of renin-angiotensin system blockers in geriatrics patients.
        date: 2020-09-09
       words: 2665
      flesch: 49
     summary: The aim of this study was to assess the relationship between angiotensin receptor blockers (ARB) and an ACE inhibitor (ACEI) use and in-hospital mortality in geriatric patients hospitalized for COVID-19. The aim of this study was to assess the 51 relationship between ACEI/ARB and in-hospital mortality among geriatric patients hospitalized for 52 COVID-19.
    keywords: acei; angiotensin; arb; covid-19; geriatric; mortality; patients
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        item: #6090 of 7819
          id: cord-333986-xkx181ek
      author: Hall, Mary-Frances E.
       title: Exercise for Older Adults Improves the Quality of Life in Parkinson’s Disease and Potentially Enhances the Immune Response to COVID-19
        date: 2020-09-06
       words: 7083
      flesch: 35
     summary: A prospective study in humans assessing the dose-response relationship between moderate walking/running energy expenditure and pneumonia, respiratory disease, and aspiration pneumonia mortality, found that higher doses of moderate exercise decreased mortality in all three categories [50] . A prospective study in humans assessing the dose-response relationship between moderate walking/running energy expenditure and pneumonia, respiratory disease, and aspiration pneumonia mortality, found that higher doses of moderate exercise decreased mortality in all three categories [50] .
    keywords: activity; cells; covid-19; disease; exercise; intensity; motor; parkinson; response; system; training
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        item: #6091 of 7819
          id: cord-333998-z2zahfv9
      author: Taxbro, Knut
       title: Rhabdomyolysis and acute kidney injury in severe COVID-19 infection
        date: 2020-09-02
       words: 2027
      flesch: 44
     summary: Further research designed to better understand the pathophysiological mechanisms behind COVID-19 related rhabdomyolysis would be of great value. The patient survived and was discharged from intensive care after 12 days, returning home 23 days after hospitalisation, fully mobilised with a partially restored kidney function.
    keywords: acute; care; covid-19; patient; rhabdomyolysis
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        item: #6092 of 7819
          id: cord-333999-k92fmnq7
      author: Yang, Chih-Jen
       title: Remdesivir Use in the Coronavirus Disease 2019 Pandemic: A Mini-Review
        date: 2020-10-05
       words: 2591
      flesch: 30
     summary: Engineering (Beijing) Novel coronavirus treatment with ribavirin: Groundwork for an evaluation concerning COVID-19 A trial of lopinavir-ritonavir in adults hospitalized with severe COVID-19 An open-label cluster-randomized controlled trial of chloroquine, hydroxychloroquine or only supportive care in patients admitted with moderate to severe COVID-19 (ARCHAIC)-protocol publication Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study Effective treatment of severe COVID-19 patients with tocilizumab Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury Effect of colchicine vs standard care on cardiac and inflammatory biomarkers and clinical outcomes in patients hospitalized with coronavirus disease 2019: All compassionate-use treatments and clinical trials involved the administration of remdesivir at a 200-mg loading dose on the first day, with a 100-mg maintenance dose for 9 subsequent days 26, 28, 30, 59, 60 ; this regime is identical to that utilized in the previous Ebola trial 61 , which appears to be the model for all subsequent trials involving remdesivir.
    keywords: coronavirus; cov-2; covid-19; patients; remdesivir; sars; treatment; use
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        item: #6093 of 7819
          id: cord-334021-ex4z2b75
      author: Tupper, P.
       title: COVID-19's unfortunate events in schools: mitigating classroom clusters in the context of variable transmission
        date: 2020-10-22
       words: 7708
      flesch: 53
     summary: If, instead, we are to maintain open schools, it is necessary to prevent large school transmission clusters, even if they are expected to be rare. We describe the contrasting literature on school transmission, and argue that the apparent discrepancy can be reconciled by heterogeneity, or ``overdispersion' in transmission, with many exposures yielding little to no risk of onward transmission, but some unfortunate exposures causing sizeable onward transmission.
    keywords: case; class; cluster; covid-19; index; license; preprint; school; students; symptomatic; transmission
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        item: #6094 of 7819
          id: cord-334092-50r3h7jv
      author: Loungani, Rahul S.
       title: A care pathway for the cardiovascular complications of COVID-19: Insights from an institutional response
        date: 2020-05-03
       words: 4007
      flesch: 24
     summary: Our algorithm ( Figure 1 ) recommends evaluation of cardiac biomarkers of all confirmed COVID-19 patients requiring admission to the hospital for prognostication and during any acute decompensation to screen for cardiac dysfunction. It has helped organize our internal discussions around management of cardiovascular complications and provides clear guidance to providers on the frontlines who may be less familiar with the care of cardiovascular patients.
    keywords: acute; cardiac; cardiovascular; care; covid-19; disease; infection; injury; patients; risk
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        item: #6095 of 7819
          id: cord-334122-3c1i25vc
      author: Fahad, Ahmed Muhi
       title: Spontaneous pneumothorax as a complication in COVID‐19 male patient: A case report
        date: 2020-09-21
       words: 1317
      flesch: 53
     summary: Spontaneous pneumothorax and subcutaneous emphysema in COVID-19 patient: case report COVID-19 complicated by spontaneous pneumothorax Tension pneumothorax in a patient with COVID-19 COVID-19 with spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema A case of spontaneous pneumothorax in covid-19 pneumonia None. 1, 2 There are many cases of pneumothorax diagnosed as an initial presentation for COVID-19 infection, 1 but in our case, we report diagnosis and treatment of pneumothorax case after about 21 days of initial symptoms of COVID-19 infection and after the result of PCR was negative.
    keywords: covid-19; infection; patient; pneumothorax
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        item: #6096 of 7819
          id: cord-334124-w9jww3hk
      author: Murphy, David L
       title: Occupational exposures and programmatic response to COVID-19 pandemic: an emergency medical services experience
        date: 2020-09-21
       words: 4095
      flesch: 46
     summary: In response, EMS was using large quantities of PPE to address this uncertainty, though the prevalence of confirmed COVID-19 EMS encounters was estimated to be less than 5%. We used χ 2 test for trend to evaluate whether adequate PPE use and EMS provider exposure changed over time, where calendar time was the independent variable and EMS provider exposure (or adequate PPE use) was the dependent variable.
    keywords: county; covid-19; ems; encounters; exposure; patients; ppe; providers; use
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        item: #6097 of 7819
          id: cord-334179-cjgsr7xr
      author: Al Kasab, Sami
       title: International experience of mechanical thrombectomy during the COVID-19 pandemic: insights from STAR and ENRG
        date: 2020-08-25
       words: 3270
      flesch: 36
     summary: In COVID-19 positive patients, the median age was 58 (IQR 50-71) with a range of 35-98, and three patients were younger than 50 years of age. Another limitation is that not all MT patients in our study were tested for COVID-19 which may have resulted in missing some of asymptomatic COVID-19 patients.
    keywords: centers; covid-19; data; intubation; patients; stroke; study
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        item: #6098 of 7819
          id: cord-334184-2zjbwmqn
      author: Weinstein, B.
       title: A methodological blueprint to identify COVID-19 vulnerable locales by socioeconomic factors, developed using South Korean data
        date: 2020-10-27
       words: 3230
      flesch: 46
     summary: Principal component analysis created composite indexes for each SES factor, while Geographically Weighted Negative Binomial Regressions mapped a continuous surface of COVID-19 risk for South Korea. Population mobility elevated COVID-19 risk only in the early phase for South Korea's northern, easter, and western parts.
    keywords: covid-19; health; license; medrxiv; phase; preprint; risk
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        item: #6099 of 7819
          id: cord-334188-bggt1i2e
      author: Solari, Domenico
       title: The nose lid for the endoscopic endonasal procedures during COVID-19 era: technical note
        date: 2020-08-11
       words: 2607
      flesch: 36
     summary: Nonetheless, it remains advisable to strictly adhere to COVID-19 protocols and carefully evaluate patients and procedures, in order to ensure safety and eventually limit the contagion. Helmet modification to PPE with 3D printing during the COVID-19 pandemic at Duke University Medical Center: a novel technique SAGES and EAES recommendations for minimally invasive surgery during COVID-19 pandemic Safety recommendations for evaluation and surgery of the head and neck during the COVID-19 pandemic Covid-19 patients and surgery: guidelines and checklist proposal Letter: The Risk of COVID-19 infection during neurosurgical procedures: a review of severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) modes of transmission and proposed neurosurgery-specific measures for mitigation Applications of 3D printing technology to address COVID-19 related supply shortages COVID-19 pandemic: effects and evidence-based recommendations for otolaryngology and head and neck surgery practice High risk of COVID-19 infection for head and neck surgeons Endonasal neurosurgery during the COVID-19 pandemic: the Singapore perspective Sichuan University Covid-ERG (2020) Epidemiology, treatment, and epidemic prevention and control of the coronavirus disease 2019: a review Letter: precautions for endoscopic transnasal skull base surgery during the COVID-19 pandemic
    keywords: covid-19; lid; mask; nose; pandemic; patients; surgery
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        item: #6100 of 7819
          id: cord-334217-ejgdzc70
      author: Homolak, J.
       title: Preliminary analysis of COVID-19 academic information patterns: a call for open science in the times of closed borders
        date: 2020-06-25
       words: 4958
      flesch: 40
     summary: In conclusion, we evaluate the availability of COVID-19 data as suboptimal up to this point, and argue that more mindful data sharing practices could have yielded faster and better scientific solutions in this scenario. Preliminary data suggest that COVID-19 pandemic resulted in generation of a large amount of scientific data, and demonstrates potential problems regarding the information velocity, availability, and scientific collaboration in the early stages of the pandemic.
    keywords: analysis; articles; covid-19; data; fig; information; journal; pandemic
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        item: #6101 of 7819
          id: cord-334220-sqvfr31q
      author: Messina, Francesco
       title: Looking for pathways related to COVID-19 phenotypes: Confirmation of pathogenic mechanisms by SARS-CoV-2 - Host interactome
        date: 2020-11-03
       words: 4228
      flesch: 28
     summary: We provide a network analysis on protein–protein interactions (PPI) between viral and host proteins to better identify host biological responses, induced by both whole proteome of SARS-CoV-2 and specific viral proteins. The ubiquitin proteasome system deletes viral proteins to control the infection, but the virus can use them for its propagation (34) .
    keywords: cov-2; covid-19; host; human; infection; interactions; interactome; pathways; patients; proteins; sars
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        item: #6102 of 7819
          id: cord-334235-ymsiihwd
      author: Gray, Belinda
       title: Patients with Genetic Heart Disease and COVID-19: A Cardiac Society of Australia and New Zealand (CSANZ) Consensus Statement
        date: 2020-04-30
       words: 1182
      flesch: 39
     summary: • We recommend that Brugada syndrome patients with fever that is unresponsive to paracetamol should seek urgent specialist cardiology advice as they may require more intensive monitoring. However, we have identified areas of consensus among specialists from the Cardiac Society of Australia and New Zealand (CSANZ) Cardiovascular Genetics Diseases Council with regards to managing patients with genetic heart disease in this current COVID-19 pandemic.
    keywords: covid-19; patients; risk
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        item: #6103 of 7819
          id: cord-334268-n2hon61o
      author: Ren, Yanfang
       title: Risk for dental healthcare professionals during the COVID-19 global pandemic: an evidence-based assessment
        date: 2020-07-18
       words: 6871
      flesch: 37
     summary: Our literature review focused on the following areas: prevalence of asymptomatic COVID-19 patients in the community, probability and potential outcomes from transmission from asymptomatic patients, effectiveness of PPE (N95 masks), and the infection fatality rate of COVID-19. Information on saliva viral load and viability in COVID-19 patients, especially in asymptomatic patients, are scarce.
    keywords: asymptomatic; cases; cov-2; covid-19; dental; infection; patients; risk; sars; transmission
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        item: #6104 of 7819
          id: cord-334278-ajdjfzd2
      author: Gilis, M.
       title: Caractéristiques de la COVID-19 chez les patients âgés de 75 ans et plus, hospitalisés
        date: 2020-09-30
       words: 2157
      flesch: 63
     summary: (0,4 %), Enterovirus -4 (0,9 %), M. pneumoniae -1 (0,2 %), Virus Respiratoire syncytial -1 (0,2 %), infection mixte hors SARS-CoV-2 -4 (0,9 %). Les symptômes d'anosmie, fièvre et céphalées étaient plus fréquemment présents chez les sujets avec SARS-CoV2 comparés aux autres pathogènes (respectivement 26,3 % vs 2,7 %, p < 0,00001 ; 78,9 % vs 64,9 %, p < 0,02 ;
    keywords: ans; des; les; patients; sars; une; été
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        item: #6105 of 7819
          id: cord-334280-qs40g1fz
      author: Jella, Tarun K.
       title: Geospatial Distribution of Neurosurgeons Age 60 and Above Relative to the Spread of COVID-19
        date: 2020-10-14
       words: 1739
      flesch: 50
     summary: key: cord-334280-qs40g1fz authors: Jella, Tarun K.; Desai, Ansh; Jella, Taral; Steinmetz, Michael; Kimmell, Kristopher; Wright, James; Wright, Christina Huang title: Geospatial Distribution of Neurosurgeons Age 60 and Above Relative to the Spread of COVID-19 date: 2020-10-14 journal: World Neurosurg DOI: 10.1016/j.wneu.2020.10.037 sha: doc_id: 334280 cord_uid: qs40g1fz Objective To perform an ecological study in order to analyze the geospatial distribution of neurosurgeons ≥ 60 years old and compare these data with the spread of COVID-19 across the; U.S. Methods Data regarding the distribution of COVID-19 cases was collected from the Environmental Systems Research Institute and demographic statistics from the American Association of Medical Colleges 2019State Workforce Reports. Results As of July 5, 2020, the 10 states with the highest number of COVID-19 cases showed older neurosurgical workforce proportions (the proportion of active surgeons aged 60 years or older) ranging from 20.6% to 38.9%.
    keywords: covid-19; data; neurosurgeons; years
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        item: #6106 of 7819
          id: cord-334298-b3uv6310
      author: Fang, Xinyu
       title: Depressive symptoms in the front-line non-medical workers during the COVID-19 outbreak in Wuhan
        date: 2020-07-16
       words: 3698
      flesch: 38
     summary: Conclusion: The findings of the present study suggest the targeted psychological intervention measures should be developed to improve the mental health of non-medical workers on the front-line of COVID-19 epidemic, especially the females and younger individuals. Our results demonstrated that non-medical workers working in the hardest-hit areas during major public health events have serious psychological problems.
    keywords: covid-19; depression; health; line; medical; workers
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        item: #6107 of 7819
          id: cord-334300-hnrmaytm
      author: Ventura Fernandes, Bianca H
       title: Zebrafish studies on the vaccine candidate to COVID-19, the Spike protein: Production of antibody and adverse reaction
        date: 2020-10-20
       words: 1803
      flesch: 24
     summary: key: cord-334300-hnrmaytm authors: Ventura Fernandes, Bianca H; Feitosa, Natália Martins; Barbosa, Ana Paula; Bomfim, Camila Gasque; Garnique, Anali M. B.; Gomes, Francisco I. F.; Nakajima, Rafael T.; Belo, Marco A. A.; Eto, Silas Fernandes; Fernandes, Dayanne Carla; Malafaia, Guilherme; Manrique, Wilson G.; Conde, Gabriel; Rosales, Roberta R. C.; Todeschini, Iris; Rivero, Ilo; Llontop, Edgar; Sgro, German G.; Oka, Gabriel Umaji; Bueno, Natalia F; Ferraris, Fausto K.; de Magalhaes, Mariana T. Q.; Medeiros, Renata J.; Gomes, Juliana M. M; de Souza Junqueira, Mara; Conceição, Katia; Pontes, Letícia G.; Condino-Neto, Antonio; Perez, Andrea C.; Barcellos, Leonardo J. G.; Correa junior, Jose Dias; Dorlass, Erick G.; Camara, Niels O. S; Durigon, Edison Luiz; Cunha, Fernando Q.; Nóbrega, Rafael H.; Machado-Santelli, Glaucia M.; Farah, Chuck; Veras, Flávio P; Galindo-Villegas, Jorge; Costa-Lotufo, Leticia; Cunha, Thiago M.; Chammas, Roger; Guzzo, Cristiane R.; Carvalho, Luciani R; Charlie-Silva, Ives title: Zebrafish studies on the vaccine candidate to COVID-19, the Spike protein: Production of antibody and adverse reaction date: 2020-10-20 journal: bioRxiv DOI: 10.1101/2020.10.20.346262 sha: doc_id: 334300 cord_uid: hnrmaytm Establishing new experimental animal models to assess the safety and immune response to the antigen used in the development of COVID-19 vaccine is an imperative issue. The zebrafish reference genome sequence 906 and its relationship to the human genome Zebrafish as an 909 alternative animal model in human and animal vaccination research Potential of mucoadhesive 912 nanocapsules in drug release and toxicology in zebrafish Zebrafish as tools for drug discovery Developing Covid-19 Vaccines at 917 Pandemic Speed A Comprehensive Review of Animal Models 920 for Coronaviruses: SARS-CoV-2, SARS-CoV, and MERS-CoV Comparison of SARS-CoV-2 923 infections among 3 species of non-human Affiliations Non-invasive bioluminescence imaging of HCoV-925 OC43 infection and therapy in the central nervous system of live mice An alpaca nanobody neutralizes 928 SARS-CoV-2 by blocking receptor interaction Equine hyperimmune globulin raised 931 against the SARS-CoV-2 spike glycoprotein has extremely high neutralizing 932 titers Development of a 934 hyperimmune equine serum therapy for COVID-19 in Argentina Serological survey of SARS-CoV-2 for experimental, 937 domestic, companion and wild animals excludes intermediate hosts of 35 938 different species of animals The Zebrafish Disease and Drug Screening Model: A Strong 941 Ally Against Covid-19 Tracking Mechanisms of Viral Dissemination In Vivo A Contemporary View of Coronavirus 946 Antibody responses to SARS-CoV-2 in 948 patients with COVID-19 Maternal transfer and protective role of 951 antibodies in zebrafish Danio rerio Role of maternally derived immunity in fish Breast Milk-fed&nbsp;Infant of COVID-956 19&nbsp SARS-CoV-2 S1 and S2 subunits-and nucleocapsid protein-reactive SIgM/IgM IgA antibodies in human milk Acute transverse myelitis after 963 COVID-19 pneumonia Pathological findings of COVID-19 associated with 966 acute respiratory distress syndrome Patients -An MRI-based 3-month Follow-up Study Cerebral Venous Thrombosis Associated 972 with COVID-19 Effects of COVID-19 on the Nervous System Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the 981 Absence of Encephalitis in Mice Transgenic for Human ACE2 Pathological study of the 2019 novel coronavirus 984 disease (COVID-19) through postmortem core biopsies COVID-19 Infection 987 and Neurological Complications: Present Findings and Future Predictions COVID-19-associated acute necrotizing 990 myelitis Pathogenesis and Diagnosis of Viral 993 Infections of the Nervous System Neurologic and Radiographic Findings 996 Associated With COVID-19 Infection in Children
    keywords: animal; cov-2; covid-19; human; sars; study; zebrafish
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        item: #6108 of 7819
          id: cord-334309-rddznfax
      author: Craver, Randall
       title: Fatal Eosinophilic Myocarditis in a Healthy 17-Year-Old Male with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2c)
        date: 2020-05-13
       words: 1678
      flesch: 42
     summary: Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province Cardiac troponin I in patients with coronavirus disease 2019 (COVID-19): Evidence from a meta-analysis Coronavirus fulminant myocarditis saved with glucocorticoid and human immunoglobulin Cardiovascular considerations for patients, health care workers, and health systems during the coronavirus disease 2019 (COVID-19) pandemic Is there an association between COVID-19 mortality and the renin-angiotensin system-a call for epidemiologic investigations Gross examination report of a COVID-19 death autopsy Pathological findings of COVID-19 associated with acute respiratory distress syndrome Clinical characteristics of novel coronavirus disease 2019 (COVID-19) in newborns, infants and children Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults Epidemiological characteristics of 2019 novel coronavirus family clustering in Zhejiang Province Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Eosinophilic Myocarditis: Characteristics, Treatment, and Outcomes Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19) Case series from institutions performing autopsies on COVID-19 patients may at future time further define myocardial pathology as seen in this patient.
    keywords: coronavirus; covid-19; disease; myocarditis; sars
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        item: #6109 of 7819
          id: cord-334311-i88ccp9w
      author: Robb, Catherine E.
       title: Associations of Social Isolation with Anxiety and Depression During the Early COVID-19 Pandemic: A Survey of Older Adults in London, UK
        date: 2020-09-17
       words: 6097
      flesch: 38
     summary: The older age-group is poorly represented within most of reported studies, to date. These findings indicate that an increase in loneliness was most likely due to the circumstances surrounding COVID-19 social isolation and was not pre-existing.
    keywords: anxiety; components; covid-19; depression; health; isolation; loneliness; risk; study; women
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        item: #6110 of 7819
          id: cord-334313-v2syspu6
      author: Long, S. Wesley
       title: Molecular Architecture of Early Dissemination and Evolution of the SARS-CoV-2 Virus in Metropolitan Houston, Texas
        date: 2020-05-03
       words: 4531
      flesch: 42
     summary: GISAID sequences containing greater than 1% N characters, and Houston sequences with greater than 5% N characters were removed from consideration. Machine learning models were trained to predict patient metadata categories including mortality, length of stay, inpatient versus outpatient status, ICU admission, overall outcome, gender, age, and ethnicity from viral sequence data.
    keywords: acid; amino; cov-2; covid-19; disease; houston; patients; sars; strains; viral; virus
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        item: #6111 of 7819
          id: cord-334324-remrcm2q
      author: Kunal, Shekhar
       title: Cardiovascular complications and its impact on outcomes in COVID-19
        date: 2020-11-04
       words: 3297
      flesch: 40
     summary: Summary of a report of 72,314 cases from the Chinese Center for Disease Control and Prevention Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis Clinical characteristics of 138 hospitalized patients with 2019 novel Coronavirus-Infected pneumonia in Wuhan Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study Cardiac involvement in a patient with Coronavirus Disease 2019 (COVID-19) Myocarditis in a patient with COVID-19: a cause of raised troponin and ECG changes COVID-19 complicated by acute pulmonary embolism and right-sided heart failure Initial ELSO Guidance Document: ECMO for COVID-19 patients with severe cardiopulmonary failure Acute pulmonary embolism associated with COVID-19 pneumonia detected by pulmonary CT angiography Cardiac and arrhythmic complications in patients with COVID-19 Novel coronavirus 19 (COVID-19) associated sinus node dysfunction: a case series Urgent guidance for navigating and circumventing the QTc-Prolonging and Torsadogenic potential of possible pharmacotherapies for Coronavirus Disease 19 (COVID-19) The QT interval in patients with COVID-19 treated with hydroxychloroquine and azithromycin Assessment of QT Intervals in a case series of patients with Coronavirus Disease 2019 (COVID-19) infection treated with Hydroxychloroquine alone or in combination with Azithromycin in an intensive care unit Risk of QT Interval prolongation associated with use of Hydroxychloroquine with or without concomitant Azithromycin among hospitalized patients testing positive for Coronavirus Disease Neutrophil to lymphocyte ratio as prognostic and predictive factor in patients with coronavirus disease 2019: Limited data exists regarding the involvement of cardiovascular system in COVID-19 patients.
    keywords: acute; cardiac; coronavirus; covid-19; injury; patients
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        item: #6112 of 7819
          id: cord-334341-cpol6xfz
      author: Mattei, Tobias A.
       title: The Impact of the COVID-19 Pandemic on Spine Care Providers and Patients
        date: 2020-05-07
       words: 1770
      flesch: 33
     summary: Overall, the indirect effects of the COVID-19 pandemic upon spinal care seems far more meaningful and noticeable. As a spine surgery community we are committed to both maintaining the standards of excellence in spinal care even (and especially) during critical times, as well as to a proactive attitude in assisting our institutions through our unique insight into the natural history and outcomes of spinal disorders in order to prioritize care and optimize resources allocation.
    keywords: care; covid-19; pandemic; patients; spinal
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        item: #6113 of 7819
          id: cord-334360-bor30e5j
      author: Manganelli, Fiore
       title: Brainstem involvement and respiratory failure in COVID-19
        date: 2020-05-29
       words: 1020
      flesch: 46
     summary: Our data, though limited, indicate that brainstem involvement may play a role in respiratory failure and perhaps in the high death rate of COVID-19 patients. In conclusion, our data, though limited, indicate that brainstem involvement may play a role in respiratory failure [4] and perhaps in the high death rate of COVID-19 patients.
    keywords: covid-19; failure; patients
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        item: #6114 of 7819
          id: cord-334367-w96iqo6q
      author: Devlin, John W.
       title: Strategies to Optimize ICU Liberation (A to F) Bundle Performance in Critically Ill Adults With Coronavirus Disease 2019
        date: 2020-06-12
       words: 4229
      flesch: 28
     summary: Although multiple studies demonstrate the salutary impact of Bundle use on ICU patient care, outcomes, and healthcare costs in non-COVID-19 patients (21) (22) (23) (24) , important COVID-19-related issues and barriers may preclude the routine use of the Bundle in this population, particularly at centers experiencing a surge of critically ill adults with COVID-19. Society of Critical Care Medicine and the American Society for Parenteral and Enteral Nutrition Incidence of propofol-related infusion syndrome in critically ill adults: A prospective, multicenter study Early neuromuscular blockade in the acute respiratory distress syndrome Clinical practice guidelines for sustained neuromuscular blockade in the adult critically ill patient Demand for Ventilator Drugs 'Unprecedented Repurposing valproate, enteral clonidine, and phenobarbital for comfort in adult ICU patients: A literature review with practical considerations The Medical Letter on Drugs and Therapeutics: Some Drugs for COVID-19.
    keywords: adults; bundle; care; covid-19; critical; delirium; icu; pain; patients; sedation; strategies; use
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        item: #6115 of 7819
          id: cord-334388-w66h9g9d
      author: Jack, Dominic
       title: Favorable outcomes after COVID-19 infection in multiple sclerosis patients treated with cladribine tablets
        date: 2020-08-27
       words: 1128
      flesch: 47
     summary: key: cord-334388-w66h9g9d authors: Jack, Dominic; Nolting, Axel; Galazka, Andrew title: Favorable outcomes after COVID-19 infection in multiple sclerosis patients treated with cladribine tablets date: 2020-08-27 journal: Cold Spring Harb Perspect Med 8 Clinical characteristics and outcomes in patients with coronavirus disease 2019 and multiple sclerosis Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy Type I and type III interferons -induction, signaling, evasion, and application to combat COVID-19 Multiple sclerosis Associations between immune-suppressive and stimulating drugs and novel COVID-19 -A systematic review of current evidence An Italian programme for COVID-19 infection in multiple sclerosis Virological assessment of hospitalized patients with COVID-2019 False negative tests for SARS-CoV-2 infection -challenges and implications Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
    keywords: covid-19; patients
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        item: #6116 of 7819
          id: cord-334391-0172afa1
      author: Gupta, Rahul
       title: The double edged interferon riddle in COVID-19 pathogenesis
        date: 2020-11-01
       words: 594
      flesch: 43
     summary: I would like to humbly add some views to it: there has been two varying reported type I interferon responses in COVID-19 pathogenesis [2] : one stating the suppression of host antiviral type I interferons (IFNs) and interferon stimulated genes (ISGs) and other stating increased expression of different ISGs, with further inductions of chemokines and cytokines [2] . key: cord-334391-0172afa1 authors: Gupta, Rahul title: The double edged interferon riddle in COVID-19 pathogenesis date: 2020-11-01 journal: Crit Care DOI: 10.1186/s13054-020-03337-z sha: doc_id: 334391 cord_uid: 0172afa1 nan In their recent article [1] , Jalkanen et al. discuss about the prospective usage of interferon beta 1 in managing COVID-19 and substantiating usage of intravenous route of administration over subcutaneous route.
    keywords: covid-19; type
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        item: #6117 of 7819
          id: cord-334413-h6n36jei
      author: Bhattacharyya, Suvanjan
       title: A Novel CFD Analysis to Minimize the Spread of COVID-19 Virus in Hospital Isolation Room
        date: 2020-09-17
       words: 2702
      flesch: 35
     summary: Progress in Computational Fluid Dynamics Characterization of infectious aero-sols in health care facilities: an aid to effective engineering controls and preventive strategies Effect of ventilation pattern on room air and contaminant distribution Disinfection of environments in healthcare and no healthcare settings potentially contaminated with SARS-CoV-2 Aerosol and surface distribution of severe acute respiratory syndrome Coronavirus 2 in hospital wards Design and simulation of isolation room for a hospital Airborne Respiratory Diseases and mechanical systems for control of microbes Role of ventilation in airborne transmission of infectious agents in the built environment-a multidisciplinary systematic review Improved Strategy to Control Aerosol-Transmitted Infections in a Hospital Suite Methodology for minimizing risk from airborne organisms in hospital isolation rooms Two-equation eddy-viscosity turbulence models for engineering applications COVID 19: Guidelines on disinfection of common public places including offices Indirect effects of COVID-19 on the environment Temperature significantly changes COVID-19 transmission in (sub) tropical cities of Brazil Outbreak of a new coronavirus: what anaesthetists should know COVID-19 transmission in Mainland China is associated with temperature and humidity: A time-series analysis Effects of flow control in the presence of asymmetric inflows in twin air-intake. It is absolutely essential to reduce the risk of airborne infection transmission to the lowest possible level in hospital isolation rooms to protect the lives of doctors, nurses and other health care workers, and simultaneously, flatten the curve of COVID- This particular investigation was performed to offer understanding the airflow patterns in the isolation room.
    keywords: air; covid-19; isolation; room; study; temperature; virus
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        item: #6118 of 7819
          id: cord-334416-4tslee57
      author: Sen-Crowe, Brendon
       title: Social distancing during the COVID-19 pandemic: Staying home save lives
        date: 2020-04-02
       words: 1039
      flesch: 52
     summary: The rate of COVID-19 infection is largely determined by its reproductive number (R 0 ) key: cord-334416-4tslee57 authors: Sen-Crowe, Brendon; McKenney, Mark; Elkbuli, Adel title: Social distancing during the COVID-19 pandemic: Staying home save lives date: 2020-04-02 journal: Am J Emerg Med DOI: 10.1016/j.ajem.2020.03.063 sha: doc_id: 334416 cord_uid: 4tslee57 nan The severity of the COVID-19 outbreak is the greatest public health threat caused by a respiratory virus since 1918.
    keywords: covid-19; distancing; infection
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        item: #6119 of 7819
          id: cord-334425-6zrmavps
      author: SanJuan-Reyes, Sindy
       title: COVID-19 in the environment
        date: 2020-08-14
       words: 2088
      flesch: 10
     summary: The following review aims to analyze information on the implications of COVID-19 infection on human health and the impact of its presence on the environment, from its transmission capacity and the role of air pollutants and climatological factors to reducing the air pollution during confinement. Until now, there are no specific pharmacological treatment or vaccines against COVID-19 infection 104 for potential therapy in humans, so extensive isolation measures and the use of disinfection products 105 have been implemented to reduce their transmission from person to person.
    keywords: coronavirus; covid-19; disease; sars; transmission
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        item: #6120 of 7819
          id: cord-334431-qn2c83in
      author: Aaronson, Emily Loving
       title: Emerging palliative care innovations in the ED: a qualitative analysis of programmatic elements during the COVID-19 pandemic
        date: 2020-11-06
       words: 4756
      flesch: 45
     summary: For this qualitative study of PC programs in EDs, semi-structured interviews were conducted with ED and PC clinicians between June 30, 2020 and August 18, 2020. Several interviewees reported that PC's presence in the ED enabled ED patients to have their emotions attended to in a way that they suspected otherwise may not have happened.
    keywords: care; clinicians; covid; innovations; models; patients; programs
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        item: #6121 of 7819
          id: cord-334445-rk0jay4a
      author: Mistrangelo, M.
       title: Do we really need guidelines for HRA during the COVID‐19 pandemic?
        date: 2020-05-25
       words: 841
      flesch: 53
     summary: Guidelines for the Practice of HRA in the Era of COVID-19 Human papillomavirus, anal cancer, and screening considerations among HIV-infected individuals Anal human papillomavirus infection and associated neoplastic lesions in men who have sex with men: a systematic review and meta-analysis A phase II clinical study to assess the feasibility of self and partner anal examinations to detect anal canal abnormalities including anal cancer In spite of this IANS proposed its guidelines for the use of HRA in anal cancer and its precursors.
    keywords: covid-19; hra
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        item: #6122 of 7819
          id: cord-334477-vdpaxj4e
      author: Koh, Jiayun
       title: Epidemiological and Clinical Characteristics of Cases During the Early Phase of COVID-19 Pandemic: A Systematic Review and Meta-Analysis
        date: 2020-06-11
       words: 5066
      flesch: 45
     summary: Across the 11 case series and cross-sectional studies selected from full-text review, there were different proportions of case severities-seven studies consisted entirely of COVID-19 pneumonia cases (n = 482) (25-28, 30, 33, 35 (29) . This systematic review and meta-analysis aims to review the epidemiological and clinical characteristics of COVID-19 cases in the early phase of the COVID-19 pandemic.
    keywords: 2019; cases; china; coronavirus; covid-19; novel; patients; pneumonia; studies
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        item: #6123 of 7819
          id: cord-334480-aosmo568
      author: Gebrie, D.
       title: Efficacy of remdesivir versus placebo for the treatment of COVID-19: A protocol for systematic review and meta-analysis of randomized controlled trials
        date: 2020-04-14
       words: 2198
      flesch: 46
     summary: https://doi.org/10.1101/2020.04.09.20059196 doi: medRxiv preprint review authors exist, the third author will be consulted and consensus will be made through discussion. We will conduct funnel plot and Egger test to check any possible reporting bias if a sufficient number of included studies (at least 10 trials) are available in this study [31] .
    keywords: analysis; coronavirus; covid-19; meta; preprint; review
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        item: #6124 of 7819
          id: cord-334490-42gykxdx
      author: Kammerlander, Andreas A.
       title: COVID-19: frequently asked questions to the cardiologist
        date: 2020-07-24
       words: 1741
      flesch: 30
     summary: Furthermore, cardiac injury in patients with COVID-19, defined as a rise of highly sensitive troponin levels, has been identified as a strong predictor of morbidity and mortality in COVID-19 patients. In critically ill patients, VTE is frequent but seems to occur much more frequently in patients with COVID-19, with reported incidence rates of up to one third in ICU patients [22] .
    keywords: ace; arb; coronavirus; covid-19; disease; patients
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        item: #6125 of 7819
          id: cord-334495-7y1la856
      author: Agricola, Eustachio
       title: Heart and Lung Multimodality Imaging in COVID-19
        date: 2020-06-24
       words: 6796
      flesch: 25
     summary: As many as 40% hospitalized patients presenting with COVID-19 have pre-existing history of cardiovascular disease and current estimates report a proportion of myocardial injury in COVID-19 patients ranging up to 12%. The use of integrated heart and lung multimodality imaging plays a central role in different clinical settings and is essential in diagnosis, risk stratification and management of COVID-19 patients.
    keywords: acute; cardiac; chest; cov-2; covid-19; disease; imaging; involvement; lung; lus; patients; respiratory; risk; sars
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        item: #6126 of 7819
          id: cord-334518-mjr6u7ak
      author: Hu, X.
       title: Development and clinical application of a rapid and sensitive loop-mediated isothermalamplification test for SARS-CoV-2 infection
        date: 2020-05-23
       words: 5165
      flesch: 44
     summary: Additionally, nasopharyngeal swabs from COVID-19 patients had a higher positive rate than sputum specimens in both the RT-qPCR and LAMP assays. Respiratory samples were collected and tested with LAMP and the results were compared with those obtained by RT-qPCR.
    keywords: cov-2; covid-19; lamp; license; medrxiv; preprint; qpcr; samples; sars
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        item: #6127 of 7819
          id: cord-334522-gi7zj70m
      author: Gersons, Berthold P. R.
       title: Can a ‘second disaster’ during and after the COVID-19 pandemic be mitigated?
        date: 2020-09-23
       words: 3070
      flesch: 34
     summary: Extensive research on previous disasters has yielded a usable definition of disaster as the result of exposure to a hazard that threatens personal safety, disrupts community and family structures, and results in personal and societal loss, creating demands that exceed existing resources (Ursano, Fullerton, Weisaeth, & Raphael, 2007) . Underlying deep racial and socioeconomic divides SARS control and psychological effects of quarantine Five essential elements of immediate and mid□term mass trauma intervention: Empirical evidence The organization of post-disaster psychosocial support in the netherlands: A meta-synthesis Trauma-informed responses in addressing public mental health consequences of the COVID-19 pandemic: Position paper of the European Society for Traumatic Stress Studies (ESTSS) Occurrence, prevention, and management of the psychological effects of emerging virus outbreaks on healthcare workers: Rapid review and meta-analysis Evaluation of national pandemic management policies-A hazard analysis of critical control points approach Long-term psychiatric morbidities among SARS survivors The Spanish influenza pandemic: A lesson from history 100 years after 1918 Learning for the future: The challenge of disaster Mental health services required after disasters: Learning from the lasting effects of disasters Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study Reconsidering the phases of disasters Increased co-morbidity of depression and post-traumatic stress disorder symptoms and common risk factors in intensive care unit survivors: A two-year follow-up study The role of community in disaster response: Conceptual models Mental health and media links based on five essential elements to promote psychosocial support for victims: The case of the earthquake in Chile in 2010
    keywords: community; covid-19; disasters; groups; health; healthcare; pandemic; social; threat
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        item: #6128 of 7819
          id: cord-334532-r5lnjsvl
      author: Rodriguez, Lindsey M.
       title: Drinking to Cope with the Pandemic: The Unique Associations of COVID-19-Related Perceived Threat and Psychological Distress to Drinking Behaviors in American Men and Women
        date: 2020-06-27
       words: 4760
      flesch: 38
     summary: The association between COVID-19 psychological distress and both peak number of drinks and typical number of drinks per occasion were moderated by gender. COVID-19 psychological distress was not differentially linked to drinking frequency and heavy drinking episodes among men and women.
    keywords: alcohol; covid-19; distress; drinking; drinks; pandemic; use; women
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        item: #6129 of 7819
          id: cord-334546-izzavogm
      author: Huang, Ian
       title: C-reactive protein, procalcitonin, D-dimer, and ferritin in severe coronavirus disease-2019: a meta-analysis
        date: 2020-07-02
       words: 3589
      flesch: 41
     summary: The outcome of interest for this study was the composite poor outcome, which comprises mortality, acute respiratory distress syndrome, need for care in an intensive care unit, and severe COVID-19. An elevated PCT was associated with an increased composite poor outcome [RR 3.92 (2.42, 6.35), p < 0.001; I(2): 85%] and its mortality (RR 6.26; I(2): 96%) and severe COVID-19 (RR 3.93; I(2): 63%) subgroups.
    keywords: analysis; covid-19; crp; dimer; outcome; patients; pct; serum
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        item: #6130 of 7819
          id: cord-334550-xb0alubj
      author: Samaddar, Arghadip
       title: The Enigma of Low COVID-19 Fatality Rate in India
        date: 2020-07-28
       words: 6415
      flesch: 38
     summary: Researchers from Translational Bioinformatics Group at International Center for Genetic Engineering and Biotechnology (ICGEB) in collaboration with the Department of Biochemistry, Jamia Hamdard, New Delhi, India, performed an integrated mutational analysis of SARS-CoV-2 genomes from different geographical locations, including India, Italy, United States, Nepal and Wuhan, and observed a novel mutation in S protein (A930V, 24351C>T) of the Indian strain, which was absent in other strains (Sardar et al., 2020) . Genomic sequence data indicate that SARS-CoV-2 has 96.2% sequence homology with a bat coronavirus RaTG13 (Zheng, 2020) , and 91% homology with a pangolin coronavirus (Zhang et al., 2020) .
    keywords: bcg; cells; coronavirus; cov-2; covid-19; disease; et al; human; indian; mutations; population; sars; strains; virus
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        item: #6131 of 7819
          id: cord-334564-bqh9jkds
      author: Raony, Ícaro
       title: Psycho-Neuroendocrine-Immune Interactions in COVID-19: Potential Impacts on Mental Health
        date: 2020-05-27
       words: 9908
      flesch: 27
     summary: Furthermore, higher serum levels of pro-inflammatory cytokines (e.g., IL-6 and IFN-γ) and chemokines were found in SARS patients with severe disease, as compared to individuals with uncomplicated SARS (44) (45) (46) . Therefore, it is possible that the increased levels of IL-6 are related to the cognitive impairments observed in SARS patients.
    keywords: axis; cov-2; covid-19; cytokines; health; immune; infection; isolation; levels; patients; sars; stress; studies; symptoms
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        item: #6132 of 7819
          id: cord-334638-au5sqzxw
      author: Dores, Artemisa R.
       title: The Use of New Digital Information and Communication Technologies in Psychological Counseling during the COVID-19 Pandemic
        date: 2020-10-21
       words: 7913
      flesch: 33
     summary: Significant correlations were negative between frequency of psychological counseling sessions and both years of professional experience, r s = −0.341, p < 0.001, and age, r s = −0.229, p = 0.017. The aspect, duration of psychological counseling sessions also displayed a significant negative correlation with age, r s = −0.209, p = 0.030.
    keywords: counseling; covid-19; icts; pandemic; psychological; psychologists; study; therapy; use
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        item: #6133 of 7819
          id: cord-334688-0i1pu8wc
      author: Martos Pérez, F.
       title: Comorbidity and prognostic factors on admission in a COVID-19 cohort of a general hospital
        date: 2020-08-19
       words: 3447
      flesch: 50
     summary: Caused by SARS-CoV-2: A Prospective Cohort Study Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan ACP risk grade: a simple mortality index for patients with confirmed or suspected severe acute respiratory syndrome coronavirus 2 disease (COVID-19) during the early stage of outbreak in Wuhan Development and external validation of a prognostic multivariable model on admission for hospitalized patients with Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Informe sobre el reporte de casos de COVID-19 Enfermedad por el coronavirus (COVID-19) Gobierno de España; 2020 abr Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal Prediction of criticality in patients with severe Covid-19 infection using three clinical features: a machine learning-based prognostic model with clinical data in Wuhan Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan Predicting COVID-19 malignant progression with AI techniques Predictors of Mortality for Patients with COVID-19 Pneumonia
    keywords: cov-2; covid-19; hospital; mean; mortality; patients; sars; study
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        item: #6134 of 7819
          id: cord-334694-7pjoaj37
      author: de Vroege, Lars
       title: UpdatesMental support for health care professionals essential during the COVID-19 pandemic
        date: 2020-07-13
       words: 549
      flesch: 43
     summary: In 2002-2003 during the SARS epidemic, health care professionals experienced physical and mental symptoms, 4 which makes the support of mental health of health care professionals key during this pandemic. However, the continuing huge pressure on mental health care professionals warrants the supporting of their mental health but regretfully, this topic received little attention.
    keywords: care; health
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        item: #6135 of 7819
          id: cord-334708-lbmktall
      author: Putman, Michael S.
       title: Publication Rate and Journal Review Time of COVID-19 Related Research
        date: 2020-08-31
       words: 438
      flesch: 43
     summary: Anecdotally, academic researchers have noticed a reduction in the amount of time journals require to review COVID-19 manuscripts. In this letter we describe the growth of this literature and the review time of COVID-19 related manuscripts.
    keywords: covid-19; review
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        item: #6136 of 7819
          id: cord-334711-58ygbyiz
      author: Hernández-Sánchez, Brizeida Raquel
       title: Psychological Factors that Lessen the Impact of COVID-19 on the Self-Employment Intention of Business Administration and Economics’ Students from Latin America
        date: 2020-07-22
       words: 8580
      flesch: 27
     summary: The role of gender stereotypes in perceptions of entrepreneurs and intentions to become an entrepreneur Development and cross-cultural application of a specific instrument to measure entrepreneurial intentions Exploratory study of job insecurity and entrepreneurial intention as correlates of counterproductive work behavior Social Foundations of Thought and Action: A Social Cognitive Theory The Impact of Terrorism and Conflicts on Growth in Asia ADB Institute Discussion Paper No. 113; ADBI Institute Self-Employment and conflict in Colombia Danger zone entrepreneurs: The importance of resilience and self-efficacy for entrepreneurial intentions The open society assesses its enemies: Shocks, disasters and terrorist attacks Business vulnerability to earthquakes and other disasters Positive and negative postdisaster psychological adjustment among adult survivors of the Southeast Asian earthquake-tsunami Startups in times of crisis-A rapid response to the COVID-19 pandemic Entrepreneurs in dark ages: Persistence of females entrepreneurs in Afghanistan The empirical exploration of intrinsic motivational processes Motivation, personality, and development within embedded social contexts: An overview of self-determination theory Self-Determination theory and the facilitation of intrinsic motivation, social development, and well-being Exercise, physical activity, and self-determination theory: A systematic review Why the self-employed are happier: Evidence from 25 European countries Differentiating autonomy from individualism and independence: A self-determination theory perspective on internalization of cultural orientations and well-being Entrepreneurial intention among university students in Malaysia: Integrating self-determination theory and the theory of planned behavior The impact of autonomy on the relationship between mentoring and entrepreneurial intentions among youth in Germany, Kenya, and Uganda College students' entrepreneurial intention: Testing an integrated model of SDT and TPB The proactive component of organizational behavior: A measure and correlates Proactive Behavior in Organizations Personal initiative (PI): An active performance concept for work in the 21st century Modeling the antecedents of proactive behavior at work Proactive personality and proactive behaviour: Perspectives on person-situation interactions Self-Efficacy: Toward a unifying theory of behavioral change Proactive personality and entrepreneurial intention: Employment and student level as moderators Bin, P. Creativity, proactive personality, and entrepreneurial intention: The role of entrepreneurial alertness From entrepreneurial intentions to behavior: The role of anticipated regret and proactive personality Firms' proactiveness during the crisis: Evidence from European data Entrepreneurial potential and potential entrepreneurs The proactive personality disposition and entrepreneurial behavior among small company presidents What do proactive people do? The impact of entrepreneurship education: A study of Iranian students' entrepreneurial intentions and opportunity identification Determinants of entrepreneurial intent: A meta-analytic test and integration of competing models A systematic literature review on entrepreneurial intentions: Citation, thematic analyses, and research agenda The relationship of entrepreneurial traits, skill, and motivation to subsequentventure growth Personality aspects of entrepreneurship: A look at five meta-analyses Effects of emotional intelligence on entrepreneurial intention and self-efficacy A downside to the entrepreneurial personality? Psychological need satisfaction as a pre-determinant of entrepreneurial intentionality Basic psychological need satisfaction, need frustration, and need strength across four cultures Basic psychological need theory: Advancements, critical themes, and future directions On psychological growth and vulnerability: Basic psychological need satisfaction and need frustration as a unifying principle Predicting entrepreneurial intentions: Incremental validity of proactive personality and entrepreneurial self-efficacy as a moderator García-Pérez-de-Lema, D. The effects of personal abilities and self-efficacy on entrepreneurial intentions
    keywords: business; covid-19; entrepreneurship; intentions; need; optimism; pandemic; perception; personality; proactiveness; psychological; satisfaction; students; study
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        item: #6137 of 7819
          id: cord-334715-902pfxyz
      author: Sirico, Domenico
       title: Cardiac imaging in congenital heart disease during the coronavirus disease-2019 pandemic: recommendations from the Working Group on Congenital Heart Disease of the Italian Society of Cardiology
        date: 2020-06-01
       words: 2549
      flesch: 32
     summary: CT and MR machine gantries, and reporting stations (monitor, mouse and keyboards) should be sanitized after every contact with suspected patients. (2) Scheduled echocardiogram in known CHD patient whose cardiac status has changed from previous ultrasound investigation but is otherwise clinically stable.
    keywords: cardiac; covid-19; gloves; hands; infection; patients; wash
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        item: #6138 of 7819
          id: cord-334716-s4mfegv7
      author: Herman, P.
       title: Corticothérapie en ORL en contexte de pandémie COVID-19
        date: 2020-05-04
       words: 843
      flesch: 45
     summary: Les auteurs tiennent à souligner que les conseils de bonne pratique énoncés dans ce texte sont Les auteurs déclarent ne pas avoir de liens d'intérêts. L’instauration de traitements par sprays nasaux de corticoïdes reste possible s’il n’existe pas d’alternative.
    keywords: dans; les
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        item: #6139 of 7819
          id: cord-334773-yw2qgv13
      author: Lisco, Giuseppe
       title: Hypothesized mechanisms explaining poor prognosis in type 2 diabetes patients with COVID-19: a review
        date: 2020-08-10
       words: 7912
      flesch: 27
     summary: Unfortunately, inconclusive deductions are currently available for considering concomitant medications favourable (as well as detrimental) factors in COVID-19 patients with T2D. Despite some putative mechanisms have been identified and some speculative hypothesis have also been formulated indicating that some anti-diabetes medications may improve clinical course in COVID-19 (pioglitazone, gliflozins, DPP-IV inhibitors, GLP-1RA), further studies are needed to clarify the issue. Considering that pancreatic islets express ACE 2 , glucose impairment in COVID-19 diabetic patients could be attributable to a partial insulin deficiency
    keywords: cardiovascular; coronavirus; cov-2; covid-19; diabetes; disease; glucose; immune; infection; obesity; patients; prognosis; response; risk; sars; t2d
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        item: #6140 of 7819
          id: cord-334776-hvgbg0gu
      author: Craig, Lyn
       title: Dual‐earner Parent Couples’ Work and Care during COVID‐19
        date: 2020-06-25
       words: 5928
      flesch: 54
     summary: Overall, paid work time was slightly lower, and unpaid work time was very much higher, during lockdown than before it. Balancing work and family can be assisted by government and workplace policies such as subsidized childcare, paid maternity and paternity leave, the right to request part time work, flexible working hours and, centrally relevantly to this paper, options to work from home (Crompton, 2006; Lewis, 2009 ).
    keywords: care; covid-19; fathers; mothers; percent; time; work
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        item: #6141 of 7819
          id: cord-334790-lav794w0
      author: Jin, Huijuan
       title: Consensus for prevention and management of coronavirus disease 2019 (COVID-19) for neurologists
        date: 2020-04-01
       words: 3564
      flesch: 46
     summary: Therefore, neurologists should be vigilant when seeing COVID-19 infected patients and look for any signs suspicious for intracranial infection, and if possible, MRI of head with and without contrast should be performed. In other patients, their temperature may drop, but their pneumonia actually progressed.
    keywords: coronavirus; cov-2; covid-19; disease; infection; patients; sars; symptoms; treatment
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        item: #6142 of 7819
          id: cord-334801-p5mxc694
      author: Van Singer, Mathias
       title: COVID-19 risk stratification algorithms based on sTREM-1 and IL-6 in emergency department
        date: 2020-10-09
       words: 2030
      flesch: 43
     summary: A recent study identified different inflammatory cytokine profiles according to the stage 97 of the disease, suggesting their usefulness for risk stratification in COVID-19 patients (13). This prospective observational cohort study of COVID-19 patients was conducted in the ED 120 of Lausanne University Hospital (CHUV), a tertiary care center in Switzerland.
    keywords: covid-19; day; intubation; oxygen; patients; strem-1
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        item: #6143 of 7819
          id: cord-334814-stswaiep
      author: Vogrig, Alberto
       title: Causality in COVID-19-associated stroke: a uniform case definition for use in clinical research
        date: 2020-08-01
       words: 1489
      flesch: 40
     summary: Even if the World Health Organization (WHO) has provided definition for suspected, probable, and confirmed COVID-19 cases, we believe that only patients with laboratory-confirmed SARS-CoV-2 should enter in the classification, in addition to clinic-radiological evidence of acute stroke (ischemic or hemorrhagic). This example suggests that the CAS criteria can be useful in identifying stroke cases more likely to be causally linked to COVID-19, irrespective of where the infection was acquired.
    keywords: cas; covid-19; criteria; stroke
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        item: #6144 of 7819
          id: cord-334830-fh8eitnh
      author: Bsteh, Gabriel
       title: Multiple sclerosis and COVID‐19: how many are at risk?
        date: 2020-09-25
       words: 2468
      flesch: 40
     summary: Our data adds to that as it shows that the overwhelming proportion of MS patients are not to be considered at high risk of COVID-19 mortality. METHODS: MS patients with at least one complete case report between January 1(st), 2015 and December 31(st), 2019 from the Innsbruck MS database (IMSD) were cross‐sectionally included.
    keywords: covid-19; mortality; patients; risk
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        item: #6145 of 7819
          id: cord-334847-lf1grybz
      author: Lynch, Holly Fernandez
       title: Regulatory Flexibility for COVID-19 Research
        date: 2020-07-07
       words: 2020
      flesch: 30
     summary: COVID-19 research has been running at a remarkable pace,(3) challenging the capacity of both investigators and institutional review boards (IRBs). This has traditionally been a lengthy process, often involving face-to-face contact with stakeholders, which will be difficult for COVID-19 research given urgency and the likely need to continue physical distancing for some time.
    keywords: covid-19; fda; irb; irbs; research; review
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        item: #6146 of 7819
          id: cord-334849-8rblgq9b
      author: LoPresti, Marissa
       title: The Role of Host Genetic Factors in Coronavirus Susceptibility: Review of Animal and Systematic Review of Human Literature
        date: 2020-08-12
       words: 7295
      flesch: 36
     summary: Human host genetic studies on coronavirus have largely been candidate-driven to date (see Tables 1 and S2 and Figures 3 and 4 for details on human studies, including specific references), though many hypothesis-free studies on COVID-19 are in various phases of completion. 46 Following up these data through host genetic studies using case and controls will help further examine variants in these and other genes.
    keywords: coronavirus; cov-2; covid-19; disease; factors; genes; host; human; infection; receptor; sars; species; studies; susceptibility
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        item: #6147 of 7819
          id: cord-334864-aak4wlgs
      author: Djalante, Riyanti
       title: COVID-19 and the ASEAN responses: Comparison and analysis through policy science
        date: 2020-10-22
       words: 3307
      flesch: 50
     summary: To review the impacts of COVID-19 at the ASEAN level and analise recent ASEAN regional responses specifically to COVID-19 under the light of existing health security cooperation framework. Cambodia has lowest confirmed cases compared to other ASEAN countries despite criticism of lack testing [17] .
    keywords: april; asean; country; covid-19; health; pandemic; response
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        item: #6148 of 7819
          id: cord-334867-ohw0chbg
      author: Ma, Hui
       title: Hospital biosecurity capacitation: Analysis and recommendations from the prevention and control of COVID-19
        date: 2020-05-27
       words: 3671
      flesch: 20
     summary: Infectious Disease Information Enlightenment of SARS, Ebola, and influenza A H1N1 on COVID-19 epidemic New progress in biosecurity medical treatment and clinical diagnosis and treatment of major infectious diseases Biosecurity discipline construction and capacity development in China Speed up the development of biosecurity science and technology in China with capacity building at the core Thoughts on the countermeasures of turning the emergency treatment stage into the continuous prevention and control stage at epidemic peak Suggestions on the reform of China's public health prevention system in COVID-19 epidemic Study on collaborative management of emergency supply chain of COVID-19 epidemic Study on dynamics of interregional collaborative allocation of emergency supplies for major infectious diseases Investigation on the core emergency capabilities of among medical staff in major infectious diseases Emergency research agenda for COVID-19: strategies for transmission and non-drug relief Analysis of the functional positioning of Chinese public health professionals under the new situation Thoughts and suggestions on modernization of disease prevention and control system Risk communication and community engagement (RCCE) readiness and response to the 2019 COVID-19 (2019-nCoV) interim guidance v2 Regional joint prevention and control of major diseases Not applicable Data sharing not applicable to this article as no datasets were generated or analyzed during the current study. This study examined the primary issues, including an absence of hospital emergency system, inadequate management and control of nosocomial infection, limited hospital laboratory capacity, and poor hospital admission capacity.
    keywords: biosecurity; control; covid-19; disease; emergency; epidemic; hospitals; infection; prevention; treatment
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        item: #6149 of 7819
          id: cord-334881-x9nxxled
      author: Di Lorenzo, Giuseppe
       title: COVID 19 therapies and anti-cancer drugs: A systematic review of recent literature
        date: 2020-05-21
       words: 3254
      flesch: 35
     summary: key: cord-334881-x9nxxled authors: Di Lorenzo, Giuseppe; Di Trolio, Rossella; Kozlakidis, Zisis; Busto, Giuseppina; Ingenito, Concetta; Buonerba, Luciana; Ferrara, Claudia; Libroia, Annamaria; Ragone, Gianluca; Ioio, Concetta dello; Savastano, Beatrice; Polverino, Mario; De Falco, Ferdinando; Iaccarino, Simona; Leo, Emilio title: COVID 19 therapies and anti-cancer drugs: A systematic review of recent literature date: 2020-05-21 journal: Crit Rev Oncol Hematol DOI: 10.1016/j.critrevonc.2020.102991 sha: doc_id: 334881 cord_uid: x9nxxled BACKGROUND: It is reasonable to think that cancer patients undergoing chemotherapy, targeted therapy or immunotherapy could have a more aggressive course if positive for Coronavirus disease CoV-2 (COVID- 19). Thus, during this COVID-19 crisis, cancer patients are regarded as a highly vulnerable group.
    keywords: cancer; coronavirus; covid-19; disease; drugs; patients; study; therapy; treatment
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        item: #6150 of 7819
          id: cord-334933-br1cr8kj
      author: Arora, Gulhima
       title: Solidarity and transparency against the COVID‐19 pandemic
        date: 2020-04-13
       words: 410
      flesch: 49
     summary: This is in sharp contrast to developed countries like Italy, whose transparency helps developing appropriate strategies. key: cord-334933-br1cr8kj authors: Arora, Gulhima; Kroumpouzos, George; Kassir, Martin; Jafferany, Mohammad; Lotti, Torello; Sadoughifar, Roxanna; Sitkowska, Zuzanna; Grabbe, Stephan; Goldust, Mohamad title: Solidarity and transparency against the COVID‐19 pandemic date: 2020-04-13 journal: Dermatol Ther DOI: 10.1111/dth.13359 sha: doc_id: 334933 cord_uid: br1cr8kj nan social distancing, and accessing health care only if symptoms are severe, may be lacking in poorer countries due to inadequate information and illiteracy.
    keywords: countries; covid-19
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        item: #6151 of 7819
          id: cord-334945-lxowaacg
      author: Luo, Yi
       title: Asymptomatic SARS-CoV-2 Infection in Household Contacts of a Healthcare Provider, Wuhan, China
        date: 2020-08-17
       words: 1806
      flesch: 38
     summary: An early report from China on 72,314 COVID-19 cases found that only 1% of SARS-CoV-2 infections were asymptomatic; however, asymptomatic close contacts were not routinely tested in that study (7) . Asymptomatic infected household contacts of healthcare workers with coronavirus disease might be underrecognized.
    keywords: asymptomatic; contacts; cov-2; covid-19; sars
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        item: #6152 of 7819
          id: cord-334955-gnu92up6
      author: Sutton, Jeannette
       title: COVID-19: Retransmission of official communications in an emerging pandemic
        date: 2020-09-16
       words: 7803
      flesch: 40
     summary: We develop a lexicon of keywords associated with risk communication about the pandemic response, then use automated coding to identify message content and message structural features. First, to assess whether message content and structure varied between the two time periods of interest (before and after the national emergency declaration), we used chi-square tests to examine the association for message content and message structural features and whether the message was published before and after March 13, 2020.
    keywords: communication; content; declaration; emergency; features; health; information; message; message retransmission; public; retransmission; threat
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        item: #6153 of 7819
          id: cord-334960-l5q5wc06
      author: Park, Su Eun
       title: Epidemiology, virology, and clinical features of severe acute respiratory syndrome -coronavirus-2 (SARS-CoV-2; Coronavirus Disease-19)
        date: 2020-04-02
       words: 3767
      flesch: 52
     summary: Summary of probable SARS cases with onset of illness from 1 World Health Organization Severe acute respiratory syndrome (SARS) Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia World Health Organization. It is notable that SARS-CoV infection was not declared a pandemic despite of 8,096 confirmed cases leading to 774 deaths during the 8-month period since the first report of SARS case on November 16, 2002 .
    keywords: coronavirus; cov; cov-2; covid-19; pneumonia; sars; syndrome; transmission
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        item: #6154 of 7819
          id: cord-334973-jemeyudi
      author: Wu, Dingye
       title: Analysis of the lymphocyte count in type 2 diabetic patients with coronavirus disease (COVID-19): A retrospective study in a centralized treatment center
        date: 2020-07-22
       words: 2430
      flesch: 48
     summary: This study aims to analyze the characteristics of lymphocyte count in COVID-19 patients with type 2 diabetes mellitus (T2DM). In summary, COVID-19 patients with T2DM experience a faster decline in lymphocyte count, have lower lymphocyte count, and longer hospital stay than non-diabetic patients.
    keywords: count; covid-19; days; lymphocyte; patients; sars
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        item: #6155 of 7819
          id: cord-335003-7ae0galy
      author: Kussmaul, William G.
       title: COVID-19 and Angiotensin-Converting Enzyme Inhibitor/Angiotensin-Receptor Blocker Therapy
        date: 2020-05-15
       words: 739
      flesch: 50
     summary: Initial fears that hypertension or its therapy uniquely contribute to COVID-19 illness seem now to have been unfounded. One might also add that there are currently insufficient outcomes data to show that they provide specific benefit during COVID-19 illness.
    keywords: angiotensin; covid-19
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        item: #6156 of 7819
          id: cord-335005-ezp4mery
      author: China, Anne
       title: Pandemics and the future of human-landscape interactions
        date: 2020-08-27
       words: 4032
      flesch: 33
     summary: While early reflections from the academic community have tended to target the microbiology, medicine, and animal science communities, this article articulates a viewpoint from a perspective of human interactions with Earth systems. This contribution articulates a viewpoint from a perspective of human interactions with Earth systems, targeting an interdisciplinary community of human-environment scholars.
    keywords: air; anthropocene; covid-19; et al; food; global; human; interactions; pandemic
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        item: #6157 of 7819
          id: cord-335007-27a3h2lo
      author: Dreyer, Nancy A.
       title: Self-reported symptoms from exposure to Covid-19 provide support to clinical diagnosis, triage and prognosis: An exploratory analysis
        date: 2020-11-03
       words: 2062
      flesch: 36
     summary: Elevated risks of severe symptoms outside the hospital were most evident among the obese and those with pulmonary comorbidity. This methodology appears to be useful in capturing relevant real world data, particularly symptom severity, without requiring physical presentation for clinical assessment, and offers valuable perspective on the true burden of illness as well as signaling those at particularly high risk of severe symptoms and, in parallel, those unlikely to be at such increased risk.
    keywords: covid+; covid-19; disease; participants; risk; symptoms
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        item: #6158 of 7819
          id: cord-335019-esttc16z
      author: Kayem, Gilles
       title: A snapshot of the Covid-19 pandemic among pregnant women in France
        date: 2020-06-04
       words: 2081
      flesch: 39
     summary: key: cord-335019-esttc16z authors: Kayem, Gilles; Alessandrini, Vivien; Azria, Elie; Blanc, Julie; Bohec, Caroline; Bornes, Marie; Bretelle, Florence; Ceccaldi, Pierre-François; Chalet, Yasmine; Chauleur, Céline; Cordier, Anne-Gael; Deruelle, Philippe; Desbrière, Raoul; Doret, Muriel; Dreyfus, Michel; Driessen, Marine; Fermaut, Marion; Gallot, Denis; Garabédian, Charles; Huissoud, Cyril; Lecarpentier, Edouard; Luton, Dominique; Morel, Olivier; Perrotin, Franck; Picone, Olivier; Rozenberg, Patrick; Schmitz, Thomas; Sentilhes, Loïc; Sroussi, Jeremy; Vayssière, Christophe; Verspyck, Eric; Vivanti, Alexandre J.; Winer, Norbert title: A snapshot of the Covid-19 pandemic among pregnant women in France date: 2020-06-04 journal: J Gynecol Obstet Hum Reprod DOI: 10.1016/j.jogoh.2020.101826 sha: doc_id: 335019 cord_uid: esttc16z OBJECTIVE: We collected a case series of pregnant women with COVID-19 in a research network of 33 French maternity units between March 1 and April 14, 2020.
    keywords: complications; covid-19; oxygen; sars; women
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        item: #6159 of 7819
          id: cord-335020-at43c8q7
      author: Porfidia, Angelo
       title: Venous thromboembolism and heparin use in COVID-19 patients: juggling between pragmatic choices, suggestions of medical societies
        date: 2020-05-04
       words: 2419
      flesch: 35
     summary: key: cord-335020-at43c8q7 authors: Porfidia, Angelo; Pola, Roberto title: Venous thromboembolism and heparin use in COVID-19 patients: juggling between pragmatic choices, suggestions of medical societies date: 2020-05-04 journal: J Thromb Thrombolysis DOI: 10.1007/s11239-020-02125-4 sha: doc_id: 335020 cord_uid: at43c8q7 nan The disease caused by coronavirus SARS-CoV-2, named COVID-19, has become a global emergency. In this article, we discuss the many doubts currently existing on the use of heparins and the correct prevention and diagnosis of VTE in COVID-19 patients, with physicians that juggle between pragmatic choices, different suggestions being released on a daily by hospital and medical societies, and the lack of solid evidence or guidelines.
    keywords: covid-19; patients; pneumonia; risk; vte
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        item: #6160 of 7819
          id: cord-335037-4wj4p5ys
      author: Annweiler, Cédric
       title: Neurological, Cognitive, and Behavioral Disorders during COVID‐19: The Nitric Oxide Track
        date: 2020-06-24
       words: 857
      flesch: 34
     summary: 5 In human COVID-19, proposed chemotherapeutic drugs to limit/counterbalance the overactivation of RAS could be ACE inhibitors (to prevent the production of angiotensin II from angiotensin I), blockers/antagonists of AT 1 R such as losartan and derivatives, and also some natural candidate peptide drugs that belong to the so-called counterregulatory RAS (i.e., angiotensin 1-7, angiotensin 1-9, alamandine, angiotensin A, and/or angiotensin IV). In RAS, angiotensin II, by acting on the vasoconstrictor type 1 angiotensin II receptor (AT 1 R), reportedly diminishes the production of NO, 9 leading to an expected decrease in NO concentrations in the brain during COVID-19, which needs to be compensated to prevent neurological cognitive and behavioral disorders.
    keywords: angiotensin; covid-19; system
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        item: #6161 of 7819
          id: cord-335038-q32ghvsv
      author: Huang, Jiao
       title: Epidemiological, virological and serological features of COVID-19 cases in people living with HIV in Wuhan City: A population-based cohort study
        date: 2020-08-17
       words: 3174
      flesch: 50
     summary: The median interval from symptom onset to viral clearance of confirmed COVID-19 cases in PLWH was 30 days in this study, which was longer than that of COVID-19 cases without HIV infection (20 days) key: cord-335038-q32ghvsv authors: Huang, Jiao; Xie, Nianhua; Hu, Xuejiao; Yan, Han; Ding, Jie; Liu, Pulin; Ma, Hongfei; Ruan, Lianguo; Li, Gang; He, Na; Wei, Sheng; Wang, Xia title: Epidemiological, virological and serological features of COVID-19 cases in people living with HIV in Wuhan City: A population-based cohort study date: 2020-08-17 journal: Clin Infect Dis DOI: 10.1093/cid/ciaa1186 sha: doc_id: 335038 cord_uid: q32ghvsv BACKGROUND: We aimed to describe the epidemiological, virological and serological features of coronavirus disease 2019 (COVID-19) cases in people living with HIV (PLWH).
    keywords: cases; covid-19; hiv; plwh; wuhan
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        item: #6162 of 7819
          id: cord-335039-o92ohoao
      author: Hu, Zhipeng
       title: Efficacy and safety of Lian-Hua Qing-Wen granule for COVID-2019: A protocol for systematic review and meta-analysis
        date: 2020-06-05
       words: 2117
      flesch: 48
     summary: Version 2 of the Cochrane risk-of-bias tool for randomized trials (RoB2) and the risk of bias in non-randomized studies of interventions (ROBINS-I) tool will be used to assess the risk of bias of randomized studies and non-randomized studies respectively, as recommended by the Cochrane handbook. Non-randomized studies have more biases and confounding than randomized studies, so the results of the 2 types of studies will be presented separately.
    keywords: clinical; coronavirus; covid-19; studies; study; treatment
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        item: #6163 of 7819
          id: cord-335051-31imf6bv
      author: Tsabouri, Sophia
       title: SPECIAL ARTICLE: Risk factors for severity in children with coronavirus-19 disease (COVID-19): A comprehensive literature review
        date: 2020-07-30
       words: 1675
      flesch: 41
     summary: Although a distinct pattern of laboratory findings has not emerged as being associated with 390 severity of the disease in pediatric cases of COVID-19, lymphopenia appears seems to be a Recovery in tracheal organ cultures 416 of novel viruses from patients with respiratory disease. 12 Infection by these 4 strains usually causes acute respiratory disease, with severe manifestations 113 in some children.
    keywords: children; coronavirus; covid-19; disease; journal
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        item: #6164 of 7819
          id: cord-335061-wn8u7u9y
      author: Zheng, Yichao
       title: A Learning-based Model to Evaluate Hospitalization Priority in COVID-19 Pandemics
        date: 2020-08-03
       words: 3473
      flesch: 43
     summary: This model is found effective to identify severe COVID-19 cases on admission, with a sensitivity of 84.6%, a specificity of 84.6%, and an accuracy of 100% to predict the disease progression toward rapid deterioration. The definition of these evaluation metrics 89.2% in discriminating severe COVID-19 cases from their non-severe counterparts 122 (Table 3) .
    keywords: cases; covid-19; disease; model; patients; study; table; variables
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        item: #6165 of 7819
          id: cord-335066-4xoo279v
      author: Ahmed, Oli
       title: Adaptation of the Bangla Version of the COVID-19 Anxiety Scale
        date: 2020-06-27
       words: 4053
      flesch: 49
     summary: As internal consistency reliabilities and composite reliability of the CAS Bangla version were higher than 0.80, this scale is suitable for screening COVID-19 anxiety among Bangladeshi people. Finally, further research should explore our recommendations, such as examining the CAS Bangla version on a clinical sample as well as its treatment for COVID-19 anxiety via an online psychotherapy.
    keywords: anxiety; bangla; cas; covid-19; item; scale; study; version
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        item: #6166 of 7819
          id: cord-335078-z7k59k8o
      author: Burton-Papp, Helmi C.
       title: Conscious prone positioning during non-invasive ventilation in COVID-19 patients: experience from a single centre
        date: 2020-07-31
       words: 3768
      flesch: 38
     summary: All NIV and prone patients (N=20) Only NIV (N=13) Age, year* 53.4 ± 8.3 54.6 ± 9.1 51.3 ± 6.8 Male sex, n (%) (55%) (42.9%) (61.5%) Duration of symptoms (days) † 7 (6) 7 (4.25) 9 (6.5) NHS England COVID-19 specific guidance suggests that prone position may be of use in NIV patients to improve ventilation/perfusion mismatch, work of breathing and oxygenation 13 .
    keywords: covid-19; data; niv; patients; positioning; proning; ventilation
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        item: #6167 of 7819
          id: cord-335095-epsi5qq7
      author: Feng, Gong
       title: Clinical Features of COVID-19 Patients in Xiaogan City
        date: 2020-08-24
       words: 2804
      flesch: 51
     summary: The objectives are to study the clinical features of COVID-19 patients and assess the relationship between the severity of COVID-19, age, and C-reactive protein (CRP) levels. This study documented COVID-19 patients.
    keywords: age; covid-19; crp; disease; levels; patients; severity; xiaogan
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        item: #6168 of 7819
          id: cord-335104-8b2tpbsh
      author: Carugno, Andrea
       title: Coronavirus disease 2019 (COVID‐19) rash in a psoriatic patient treated with Secukinumab: Is there a role for Interleukin 17?
        date: 2020-07-27
       words: 593
      flesch: 48
     summary: key: cord-335104-8b2tpbsh authors: Carugno, Andrea; Gambini, Daniele Mario; Raponi, Francesca; Vezzoli, Pamela; Robustelli Test, Elisa; Arosio, Marco Enrico Giovanni; Callegaro, Annapaola; Sena, Paolo title: Coronavirus disease 2019 (COVID‐19) rash in a psoriatic patient treated with Secukinumab: Is there a role for Interleukin 17? date: 2020-07-27 journal: Dermatol Ther DOI: 10.1111/dth.14011 sha: doc_id: 335104 cord_uid: 8b2tpbsh nan Various cutaneous manifestations have been observed in COVID-19 patients 1 and there has been worldwide concern among patients undergoing biologic therapies. [7] [8] [9] The mechanisms of COVID-19 cutaneous manifestation are still not well known.
    keywords: covid-19; patient
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        item: #6169 of 7819
          id: cord-335108-5u3578ws
      author: Fang, C.
       title: Extent of pulmonary thromboembolic disease in patients with COVID-19 on CT: relationship with pulmonary parenchymal disease
        date: 2020-07-10
       words: 2846
      flesch: 39
     summary: In conclusion, the high incidence of PTD in COVID-19 patients with severe disease undergoing CTPA, current lack of reliable risk stratification tools and symptoms of PTD overlapping with severe COVID-19 disease, raises the question of whether more CTPA studies should be performed in the second and third week of the illness. The secondary aims are (1) to assess the effectiveness of the British Society of Thoracic Imaging (BSTI) current guidance on the pattern and extent of lung parenchymal abnormalities in COVID-19, and (2) to assess whether there is any difference in the patterns and severity of pulmonary parenchymal disease on CT in COVID-19 patients with and without PTD.
    keywords: covid-19; ctpa; disease; lymph; patients; ptd; study
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        item: #6170 of 7819
          id: cord-335117-p03svmfr
      author: Mehtar, Shaheen
       title: Limiting the spread of COVID-19 in Africa: one size mitigation strategies do not fit all countries
        date: 2020-04-28
       words: 1705
      flesch: 42
     summary: However, the majority of COVID-19 cases currently being identified and reported from African countries are due to local transmission. As lockdowns and physical distancing measures are eased, proactive surveillance, case detection, and contact tracing with isolation will be required to prevent a dramatic resurgence of COVID-19 cases.
    keywords: africa; cases; countries; covid-19; distancing; health
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        item: #6171 of 7819
          id: cord-335122-8s3bcyo8
      author: Marshall, Steve
       title: COVID-19: What do we know?
        date: 2020-09-21
       words: 5253
      flesch: 28
     summary: arXiv preprintArXiv:2005.13689 Transmission routes of respiratory viruses among humans Nosocomial transmission of emerging viruses via aerosol-generating medical procedures Comparative dynamic aerosol efficiencies of three emergent coronaviruses and the unusual persistence of SARS-CoV-2 in aerosol suspensions (preprint) Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 Stability of SARS-CoV-2 in different environmental conditions The airborne lifetime of small speech droplets and their potential importance in SARS-CoV-2 transmission Small droplet aerosols in poorly ventilated spaces and SARS-CoV-2 transmission Aerosol emission and superemission during human speech increase with voice loudness Respiratory virus RNA is detectable in airborne and droplet particles Viable Influenza A Virus in Airborne Particles Expelled During Coughs versus Exhalations Influenza Other Respir Viruses Modality of human expired aerosol size distributions Short-range airborne route dominates exposure of respiratory infection during close contact Relative contributions of transmission routes for COVID-19 among healthcare professionals providing patient care Saliva is a reliable tool to detect SARS-CoV-2 WHO Scientific Brief: Criteria for releasing COVID-19 patients from isolation Virological assessment of hospitalized patients with COVID-19 Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study Temporal dynamics in viral shedding and transmissibility of COVID-19 Spatial and temporal dynamics of SARS-CoV-2 in COVID-19 patients: A systemic review Clinical and virologic characteristics of the first 12 patients with coronavirus disease 2019 (COVID-19) in the United States Prolonged virus shedding even after seroconversion in a patient with COVID-19 SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore Clinical and virological data of the first cases of COVID-19 in Europe: a case series Viral load of SARS-CoV-2 in clinical samples Viral dynamics in asymptomatic patients with COVID-19 SARS-CoV-2: The viral shedding vs infectivity dilemma. The results of hospital studies evaluating aerosolization of body fluids and respiratory droplets of SARS-CoV-1 infected patients generated during certain medical AGPs (tracheal intubation, non-invasive ventilation, bronchoscopy, etc.), suggest that airborne transmission of SARS-CoV-2 may be possible during these procedures.
    keywords: aerosol; agps; cov-2; covid-19; n95; patients; sars; studies; transmission; use; virus
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        item: #6172 of 7819
          id: cord-335137-5qt286kc
      author: Chatterjee, Swapan K.
       title: Molecular Pathogenesis, Immunopathogenesis and Novel Therapeutic Strategy Against COVID-19
        date: 2020-08-11
       words: 7137
      flesch: 38
     summary: The interaction of the virus transmembrane spike (S) glycoprotein with host cell receptors act as the determinant of the pathogenesis. This receptor recognition by viral cell leads to host cell entry of the virus in combination with S-protein priming by the host cell protease TMPRSS2.
    keywords: ace2; cell; coronavirus; cov-2; covid-19; disease; entry; et al; host; human; infection; protein; receptor; sars; spike; studies
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        item: #6173 of 7819
          id: cord-335138-37czoiq8
      author: Booz, George W.
       title: Macrophage responses associated with COVID-19: A pharmacological perspective
        date: 2020-09-11
       words: 775
      flesch: 27
     summary: Various biopharmaceuticals are being repurposed to target the cytokine storm in COVID-19 patients. Investigating 667 medicinal nicotine to prevent and treat COVID-19 The inflammatory reflex Selective inhibition of a regulatory 670 subunit of protein phosphatase 1 restores proteostasis The pivotal link between ACE2 672 deficiency and SARS-CoV-2 infection Aveolar macrophage activation and cytokine storm in the pathogenesis of severe Cytokine storm and leukocyte changes in 677 mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China 678 and emerging pathogenesis and therapy concepts Interferon-stimulated gene 681 15 enters posttranslational modifications of p53 Immune 685 cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing Characteristics of and Important Lessons From the Coronavirus 688 Disease 2019 (COVID-19) Outbreak in China:
    keywords: cov-2; covid-19; sars
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        item: #6174 of 7819
          id: cord-335140-njg0ln33
      author: Freeman, Ciara L
       title: Covid‐19 and Myeloma: what are the implications for now and in the future?
        date: 2020-05-19
       words: 3365
      flesch: 36
     summary: We also need to consider that the way we deliver care to myeloma patients may forever be changed as a result of the outbreak of COVID-19. For myeloma patients, who are frequently elderly, may have co-morbidities, variable frailty or mobility issues this is probably one of the most welcome strategies that has been employed -and perhaps will be one of the most positive changes to emerge from this pandemic (7) (8) (9) .
    keywords: article; care; copyright; covid-19; myeloma; patients; rights; risk; treatment
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        item: #6175 of 7819
          id: cord-335141-ag3j8obh
      author: Higgins, G.C.
       title: FFP3 reusable respirators for COVID-19; adequate and suitable in the healthcare setting
        date: 2020-06-30
       words: 22066
      flesch: 48
     summary: When asked Would you think other patients would like to have a similar AR leaflet before surgery and Would you like to see further AR leaflets to be developed in the future? In addition to those directly working in the respiratory, infectious, cardiology, nephrology, psychology, and ICU departments and COVID-19 patients, all members of the general population may encounter the new coronavirus.
    keywords: article; authors; care; clinic; covid-19; data; face; flap; free; hand; health; hospital; information; lymphedema; lymphorrhea; nhs; pandemic; patients; plastic; plastic surgery; practice; publication; reconstruction; risk; scar; service; skin; social; staff; study; surgeons; surgery; therapy; time; trainees; training; trauma; treatment; use; wound
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        item: #6176 of 7819
          id: cord-335168-3ofarutr
      author: Bhat, Yasmeen Jabeen
       title: Impact of COVID-19 Pandemic on Dermatologists and Dermatology Practice
        date: 2020-05-10
       words: 3364
      flesch: 34
     summary: Indian Council of Medical Research Potential of chloroquine and hydroxychloroquine to treat COVID-19 causes fears of shortages among people with systemic lupus erythematosus A case of exacerbation of psoriasis after oseltamivir and hydroxychloroquine in a patient with COVID-19: Will cases of psoriasis increase after COVID-19 pandemic? The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro Dermatology Residents and the care of COVID-19 Patients Self medications and poor compliance of dermatology patients in addition to lack of proper treatment protocols and monitoring are a serious concern in the present scenario.
    keywords: covid-19; dermatologists; dermatology; india; infection; medical; pandemic; patients; risk; use
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        item: #6177 of 7819
          id: cord-335175-7rvv2kzk
      author: Saqlain, M.
       title: Knowledge, Attitude and Practice among Healthcare Professionals regarding COVID-19: A cross-sectional survey from Pakistan
        date: 2020-04-17
       words: 4701
      flesch: 51
     summary: Although educational campaigns have increased their awareness regarding COVID-19 yet it remains unclear to what extent this knowledge can be put into practice and to what extent this practice actually reduces COVID-19 infection spread. 13.20063198 doi: medRxiv preprint knowledge compared to pharmacists [10] .
    keywords: april; attitude; covid-19; hcps; knowledge; license; medrxiv; practice; preprint
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        item: #6178 of 7819
          id: cord-335181-rvlu0h1h
      author: Haft, Jonathan W.
       title: Adult cardiac surgery during the COVID-19 Pandemic: A Tiered Patient Triage Guidance Statement
        date: 2020-04-16
       words: 1261
      flesch: 27
     summary: Acknowledging the risk for a potentially prolonged need for cardiac surgery procedure deferral, the authors have created this proposed template for physicians and interdisciplinary teams to consider in protecting their patients, institution and their highly specialized cardiac surgery team. Acknowledging the risk for a potentially prolonged need for cardiac surgery procedure deferral, the authors have created this proposed template for physicians and interdisciplinary teams to consider in protecting their patients, institution and their highly specialized cardiac surgery team.
    keywords: cardiac; covid-19; patients; surgery
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        item: #6179 of 7819
          id: cord-335185-3qi29i6n
      author: Hendry, Bruce M.
       title: Hypothesis: Pentoxifylline is a potential cytokine modulator therapeutic in COVID‐19 patients
        date: 2020-07-26
       words: 2474
      flesch: 32
     summary: a model of old drugs for new horizons Protective effects of pentoxifylline in pulmonary inflammation are adenosine receptor A2A dependent Inhibition of cytokine release from alveolar macrophages in pulmonary sarcoidosis by pentoxifylline: comparison with dexamethasone Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation Pentoxifylline suppresses renal tumour necrosis factor-alpha and ameliorates experimental crescentic glomerulonephritis in rats Pentoxifylline in prevention of radiation-induced lung toxicity in patients with breast and lung cancer: a double-blind randomized trial The inhibition of pro-inflammatory cytokines with pentoxifylline in the cardiopulmunary bypass lung Prednisolone or pentoxifylline for alcoholic hepatitis Pentoxifylline inhibits TNF-alpha production from human alveolar macrophages Bird Flu), inflammation and anti-inflammatory/analgesic drugs Necrosis factor-α signaling in macrophages Pulmonary and cardiac pathology in African American patients with COVID-19: an autopsy series from New Orleans Influenza leaves a trail to pulmonary oedema Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in COVID-19 Repositioning of pentoxifylline as an immunomodulator and regulator of the renin-angiotensin system in the treatment of COVID-19 Inhibitors of the reninangiotensin-aldosterone system and Covid-19 Immunomodulatory properties of pentoxifylline are mediated via adenosine-dependent pathways Focusing on adenosine receptors as a potential targeted therapy in human diseases SARS-CoV-2 infection and overactivation of Nlrp3 inflammasome as a trigger of cytokine storm and risk factor for damage of hematopoietic stem cells Hypercoagulation and antithrombotic treatment in coronavirus 2019: a new challenge 14 One of the largest scale clinical trials of pentoxifylline anti-inflammatory effects within the last decade, was the STOPAH trial.
    keywords: alpha; covid-19; cytokine; lung; patients; pentoxifylline; tnf
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        item: #6180 of 7819
          id: cord-335192-ezl7xgeb
      author: Lai, Paul BS
       title: COVID‐19 and surgical practice
        date: 2020-07-22
       words: 297
      flesch: 38
     summary: An interesting phenomenon was the proliferation of guidelines By making use of the online platform, surgical training and surgical education could be delivered to medical students as well as specialists, as part of their continuous medical education. The most significant impact worldwide is the suspension of elective operations as surgical patients were deprived of access to operation theatres and intensive care units.
    keywords: covid-19
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        item: #6181 of 7819
          id: cord-335203-reek3z4e
      author: Salman, M.
       title: The psychological effects of COVID-19 on frontline healthcare workers and how they are coping: a web-based, cross-sectional study from Pakistan
        date: 2020-06-05
       words: 3120
      flesch: 53
     summary: Significant differences of anxiety score were observed in age as well as placement categories (p = 0.016). Most frequently adopted coping strategy was religious coping (5.98 {+/-} 1.73) followed by acceptance (5.59 {+/-} 1.55) and coping planning (4.91 {+/-} 1.85).
    keywords: anxiety; coping; covid-19; hcws; preprint
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        item: #6182 of 7819
          id: cord-335213-0cji7tzq
      author: Dowd, Jennifer Beam
       title: Demographic science aids in understanding the spread and fatality rates of COVID-19
        date: 2020-05-05
       words: 1991
      flesch: 41
     summary: Fig. 1 contains population pyramids to illustrate how population age structure interacts with high COVID-19 mortality rates at older ages to generate large differences across populations in the number of deaths, holding constant assumed rates of infection prevalence (10%) and age−sex-specific CFRs (Italy) (14) . While population age structure is crucial for understanding those at the highest risk of mortality both across and within countries, it is also vital for understanding social distancing measures to reduce critical cases that overload the health system-aka flattening the curve.
    keywords: age; countries; covid-19; population; structure
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        item: #6183 of 7819
          id: cord-335244-kyg8rx4o
      author: Hines, Kristen
       title: Publier en contexte de pandémie de COVID-19
        date: 2020-06-09
       words: 599
      flesch: 48
     summary: Au cours des derniers mois, le JOGC a reçu un grand nombre de soumissions et de demandes de renseignements préalables concernant des articles liés à la COVID-19 dans le spectre de la santé des femmes. Cette situation reflète à la fois le besoin d'information sur ce nouveau virus et la vitesse croissante de publication des articles liés à la COVID-19.
    keywords: des; les
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        item: #6184 of 7819
          id: cord-335252-med3c01q
      author: Fovet, Thomas
       title: Prisons confinées: quelles conséquences pour les soins psychiatriques et la santé mentale des personnes détenues en France?
        date: 2020-05-08
       words: 3648
      flesch: 41
     summary: Les remaniements en lien avec le confinement donnent une visibilité accrue au fossé qui sépare la psychiatrie en milieu libre de la psychiatrie en milieu pénitentiaire. Les remaniements en lien avec le confinement donnent une visibilité accrue au fossé qui sépare la psychiatrie en milieu libre de la psychiatrie en milieu pénitentiaire.
    keywords: confinement; covid-19; des; france; health; les; milieu; personnes; prisons; pénitentiaire; sur
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        item: #6185 of 7819
          id: cord-335257-4uwoe841
      author: Cingolani, A.
       title: Baricitinib as rescue therapy in a patient with COVID-19 with no complete response to sarilumab
        date: 2020-07-08
       words: 2439
      flesch: 34
     summary: Higher plasma levels of cytokines IL-6, IL-2, IL-7, IL-10, interferon gamma inducible protein (IP10), monocyte chemoattractant protein (MCP1), macrophage inflammatory protein (MIP1A) and TNF-alpha have been found in COVID-19 patients admitted to intensive care units, and the cytokine storm syndrome was proportional to the severity of disease Some anecdotal cases have shown a promising efficacy of baricitinib in the treatment of COVID-19 patients [5] , and up to 14 clinical trials worldwide are recruiting patients so far, or are near to starting.
    keywords: baricitinib; covid-19; patient; sarilumab; therapy; treatment
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        item: #6186 of 7819
          id: cord-335265-kuc3v5m9
      author: Elghazawy, Hagar
       title: Implementation of breast cancer continuum of care in low- and middle-income countries during the COVID-19 pandemic
        date: 2020-07-27
       words: 7108
      flesch: 32
     summary: Characteristics of COVID-19 patients dying in Italy: report based on available data on Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Call for ensuring cancer care continuity during COVID-19 pandemic Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study Case fatality rate of cancer patients with COVID-19 in a New York hospital system COVID-19 rapid guideline: delivery of systemic anticancer treatments guidance Recommendations for prioritization, treatment, and triage of breast cancer patients during the COVID-19 pandemic. Coronavirus disease (COVID-19) situation reports Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak New country classifications by income level Global Health Initiatives of the International Oncology Community Radiation therapy availability in Africa and Latin America: two models of low and middle income countries COVID-19 and its ramifications for cancer patients in low-resource settings: Ghana as a case study Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries Breast cancer-thinking globally Drivers of advanced stage at breast cancer diagnosis in the multicountry African breast cancer -disparities in outcomes (ABCDO) study ASCO resource-stratified guidelines: methods and opportunities Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan COVID-19 and cancer: lessons from a pooled meta-analysis Global Cancer Observatory: Cancer Today.
    keywords: breast; cancer; care; clinical; covid-19; disease; infection; lmic; oncology; pandemic; patients; radiotherapy; risk; surgery; therapy; treatment
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        item: #6187 of 7819
          id: cord-335272-jypxi99z
      author: Sharma, Anupam Joya
       title: A cross-sectional study of psychological wellbeing of Indian adults during the Covid-19 lockdown: Different strokes for different folks
        date: 2020-09-03
       words: 9805
      flesch: 49
     summary: Moreover, both qualitative and quantitative study findings suggested that greater frequency of calling family members during lockdown could strengthen social relationships and increase social empathy. Therefore, we posit that persons belonging to the LGBT community could suffer from increased stress during lockdown.
    keywords: adults; anxiety; covid-19; family; findings; lgbt; lockdown; participants; qualitative; risk; study; symptoms; time
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        item: #6188 of 7819
          id: cord-335292-x2vjzp18
      author: Nagashima, S.
       title: The Endothelial Dysfunction and Pyroptosis Driving the SARS-CoV-2 Immune-Thrombosis
        date: 2020-06-19
       words: 3507
      flesch: 36
     summary: In this context, SARS-CoV-2 pneumocytes infection, besides, to have an essential role in inflammatory activation/dysfunction of endothelial cells, it also would lead to endothelial cell death, causing the discontinuity of the alveolar-capillary barrier, facilitating the virus to move from alveolar septum through the alveolar-capillary lumen. https://doi.org/10.1101/2020.06.17.20133124 doi: medRxiv preprint degranulate enzymes that can contribute to the breakdown of the glycocalyx of endothelial cells.
    keywords: activation; cases; cell; covid-19; endothelial; group; license; patients; preprint; pyroptosis
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        item: #6189 of 7819
          id: cord-335312-yp73z008
      author: Bergsland, Emily K.
       title: North American Neuroendocrine Tumor Society Guide for Neuroendocrine Tumor Patient Health Care Providers During COVID-19
        date: 2020-05-19
       words: 3412
      flesch: 38
     summary: Hospital resources are all routed to COVID-19 patients, there is no ventilator or ICU capacity, or operating room supplies are exhausted. If there is a pressing need for treatment, one might consider starting with a lower outpatient dose, both to avoid the need to do dosimetry (which would require additional visits to the hospital) and to avoid taking up an inpatient bed (radiation safety rooms at many centers may be located on wards designated for COVID-19 patients).
    keywords: care; covid-19; nets; patients; risk; therapy; treatment; tumor
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        item: #6190 of 7819
          id: cord-335316-x2t5h5gu
      author: Madariaga, M. L. L.
       title: Clinical predictors of donor antibody titer and correlation with recipient antibody response in a COVID-19 convalescent plasma clinical trial
        date: 2020-06-23
       words: 4330
      flesch: 40
     summary: The aim of this study was to establish a translational convalescent plasma program to investigate the relationship between clinical and serological parameters in convalescent plasma donors and define the antibody response of convalescent plasma recipients. Despite variability in donor titer, 80% of convalescent plasma recipients showed significant increase in antibody levels post-transfusion.
    keywords: antibody; blood; convalescent; covid-19; patients; plasma; rbd; recipients; spike; titer; transfusion
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        item: #6191 of 7819
          id: cord-335323-p7cv79ig
      author: DeSerres, Joshua J.
       title: Best Practice Guidelines for the Management of Acute Craniomaxillofacial Trauma During the COVID-19 Pandemic
        date: 2020-05-11
       words: 4208
      flesch: 37
     summary: For this reason, we recommend secondary correction of malunited fractures in COVID-19 positive patients for those deformities that are more easily corrected (eg, most zygoma fractures, Lefort I fractures). This has been created to ensure continued care for CMF trauma patients while attempting to minimize risk of exposure and transmission to surgeons and other healthcare providers.
    keywords: cmf; covid-19; disease; pandemic; patients; pcr; procedures; risk; trauma
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        item: #6192 of 7819
          id: cord-335347-vxl2flbn
      author: Diercks, Gillian R.
       title: Asymptomatic COVID-19 Infection in a Child with Nasal Foreign Body
        date: 2020-05-08
       words: 1916
      flesch: 33
     summary: Emerging data suggests that asymptomatic patients may carry and spread infection 7 . For procedures that cannot be delayed, preoperative testing should be considered prior to manipulations of the upper airway, even in asymptomatic patients 14 .
    keywords: asymptomatic; covid-19; nasal; patient; sars
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        item: #6193 of 7819
          id: cord-335351-8hdok02n
      author: Hashmi, Muhammad Daniyal
       title: Assessing the need for transfer to the intensive care unit for Coronavirus-19 disease: Epidemiology and risk factors
        date: 2020-10-27
       words: 3792
      flesch: 52
     summary: Co-morbid illnesses are not associated with the risk for ICU transfer while two initial lab values (ALC <0.8 10 3 /ml and ferritin >1000 ng/mL ) identify those at higher risk for ICU admission. Neither baseline clinical factors nor the CURB-65 score perform well as screening tests to categorize these subjects as likely to progress to ICU care.
    keywords: care; covid-19; icu; need; patients; risk; score; transfer
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        item: #6194 of 7819
          id: cord-335355-lcrbs2op
      author: Kunutsor, Setor K.
       title: Markers of liver injury and clinical outcomes in COVID-19 patients: A systematic review and meta-analysis
        date: 2020-05-28
       words: 1010
      flesch: 35
     summary: Taking the overall evidence together, the data supports a higher prevalence of elevated admission levels of markers of liver injury in severe or mortality due to COVID-19 disease, which suggests that patients with elevated levels of liver markers at baseline (during admission) had higher risks of developing worse outcomes in COVID-19. key: cord-335355-lcrbs2op authors: Kunutsor, Setor K.; Laukkanen, Jari A. title: Markers of liver injury and clinical outcomes in COVID-19 patients: A systematic review and meta-analysis date: 2020-05-28 journal: J Infect DOI: 10.1016/j.jinf.2020.05.045 sha: doc_id: 335355 cord_uid: lcrbs2op nan Since January 2020 when it was first isolated in China, coronavirus disease 2019 (COVID-19) has spread throughout the world and caused substantial morbidity and mortality.
    keywords: covid-19; injury; liver
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        item: #6195 of 7819
          id: cord-335373-17tcikxl
      author: Paul, Elisabeth
       title: COVID-19: time for paradigm shift in the nexus between local, national and global health
        date: 2020-04-20
       words: 3705
      flesch: 46
     summary: 26 27 One real result of fragmentation of global health governance is an inefficient division of labour, where hundreds of actors such as the WHO, Global Fund, President's Emergency Plan For AIDS Relief, United Nations Programme on HIV and AIDS, United States Agency BMJ Global Health for International Development, World Bank, the Gates Foundation and the Clinton Foundation (to name only a few) produce parallel programmes or bric-à-brac vertical health silos that have neither generated overall system strengthening in high burden countries nor allowed for effective global health policy. The global health community, national security agencies and all governments have known that a pandemic like COVID-19 was likely to come, yet global health policy has remained woefully unprepared nor fit-for-purpose.
    keywords: covid-19; diseases; global; health; paradigm; policies; public; systems; world
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        item: #6196 of 7819
          id: cord-335386-eflyypev
      author: Steinman, Jonathan Baruch
       title: Reduced development of COVID-19 in children reveals molecular checkpoints gating pathogenesis illuminating potential therapeutics
        date: 2020-10-06
       words: 5382
      flesch: 40
     summary: These potential negative impacts include how the pandemic and social distancing from other children affect psychological health, how it impacts education, and how it affects body weight and childhood obesity when getting sufficient exercise is more difficult during shelter-in-place and safe-distancing restrictions. In contrast, household contacts of positive children aged 0
    keywords: ace2; age; cells; children; cov-2; covid-19; expression; infection; sars; type; virus
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        item: #6197 of 7819
          id: cord-335404-s48psqth
      author: Mukandavire, Zindoga
       title: Quantifying early COVID-19 outbreak transmission in South Africa and exploring vaccine efficacy scenarios
        date: 2020-07-24
       words: 3578
      flesch: 40
     summary: Cumulative data for COVID-19 cases reported in South Africa from the 5 th March to 11 th April 2020 is shown in S1 Table. Following a similar approach in [37] , we use a Markov Chain Monte Carlo (MCMC) within a Bayesian framework (in R FME package [38] ) to fit the model to the cumulative data of confirmed COVID-19 cases in South Africa and estimate the magnitude of the epidemic using the basic reproductive number and quantify required vaccines' attributes to stem similar outbreaks.
    keywords: africa; covid-19; disease; epidemic; lockdown; model; south; vaccine
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        item: #6198 of 7819
          id: cord-335425-0wga3ch2
      author: Abdulsalam, Mohammad A.
       title: Generalized Status Epilepticus as a Possible Manifestation of COVID‐19
        date: 2020-07-20
       words: 718
      flesch: 49
     summary: We report a case of generalized status epilepticus as a possible initial manifestation of COVID-19 infection. To the best of our knowledge, less than a handful of these manifestations were labeled to be status epilepticus [2] [3] [4] .
    keywords: covid-19; epilepticus; status
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        item: #6199 of 7819
          id: cord-335446-8l1vfsbc
      author: Liao, M.
       title: The landscape of lung bronchoalveolar immune cells in COVID-19 revealed by single-cell RNA sequencing
        date: 2020-02-26
       words: 4720
      flesch: 52
     summary: The higher number of lung CD8 + T cells in mild patients may indicate a role of CD8 + T cells in the clearance of the virus. CD8 + T cells expressed CD8A and CD8B. The CCR7 + cells expressing CD4 and IL7R were likely CD4 + T cells, Treg cells were CTLA4 + FOXP3 + IL2RA + , and proliferating cells were TYMS + MKI67 + .
    keywords: cells; covid-19; holder; license; lung; medrxiv; patients; peer; preprint; sars
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        item: #6200 of 7819
          id: cord-335465-sckfkciz
      author: Gupta, Rishi K.
       title: Systematic evaluation and external validation of 22 prognostic models among hospitalised adults with COVID-19: An observational cohort study
        date: 2020-09-25
       words: 5056
      flesch: 27
     summary: The most discriminating univariable predictor is admission oxygen saturation (SpO2) on room air for deterioration models and patient age for mortality models. Importantly, prognostic models may have additional value in patient stratification for emerging drug therapies [6, 7] .
    keywords: covid-19; deterioration; hospital; models; mortality; patients; prediction; predictors; prognostic; risk; study
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        item: #6201 of 7819
          id: cord-335477-po201szv
      author: O'Leary, Fenton
       title: Personal Protective Equipment in the Paediatric Emergency Department during the COVID‐19 pandemic. Estimating requirements based on staff numbers and patient presentations.
        date: 2020-09-21
       words: 3201
      flesch: 53
     summary: A switch from individual patient contact PPE to staff focused, patient zoning PPE may then more effectively balance the availability of PPE against its need. The aim of this study was to identify the number of staff contacts and AGPs with patients in the Paediatric ED over a 24 hour period and attribute PPE required according to the NSW CEC guideline and compare this to the PPE required based on staff zone allocations.
    keywords: covid-19; masks; patients; ppe; risk; staff; study
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        item: #6202 of 7819
          id: cord-335510-eojmipzy
      author: Boeckmans, Joost
       title: COVID-19 and drug-induced liver injury: a problem of plenty or a petty point?
        date: 2020-04-08
       words: 1393
      flesch: 24
     summary: a first step in understanding SARS pathogenesis Clinical features of patients infected with 2019 novel coronavirus in Wuhan Models of drug induced liver injury (DILI)-current issues and future perspectives Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease Fulminant hepatic failure secondary to hydroxychloroquine Clinical and histologic features of azithromycin-induced liver injury Role of nonalcoholic fatty liver disease as risk factor for drug-induced hepatotoxicity Acetaminophen-induced liver injury in obesity and nonalcoholic fatty liver disease High rates of drug-induced liver injury in people living with HIV coinfected with tuberculosis (TB) irrespective of antiretroviral therapy timing during antituberculosis treatment: results from the starting antiretroviral therapy at three points in TB tri Coronavirus infections: epidemiological, clinical and immunological features and hypotheses Toxicogenomicsbased prediction of acetaminophen-induced liver injury using human hepatic cell systems Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-NCoV) in vitro Liver injury during highly pathogenic human coronavirus infections Pathological findings of COVID-19 associated with acute respiratory distress syndrome Liver injury in COVID-19: management and challenges Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Recent reports point to the fact that liver injury, by means of increased aminotransferase levels, more frequently occurred in severe COVID-19 cases compared to patients with mild symptoms Guan et al. 2020; Liu et al. 2020a, b; Chen et al. 2020) .
    keywords: covid-19; liver; patients
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        item: #6203 of 7819
          id: cord-335516-om7w8y0t
      author: Larsen, Julie Brogaard
       title: Platelets in Coronavirus Disease 2019
        date: 2020-04-30
       words: 1365
      flesch: 37
     summary: Clinical characteristics of coronavirus disease 2019 in China Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Hematologic parameters in patients with COVID-19 infection Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis Clinical characteristics of refractory COVID-19 pneumonia in Wuhan, China Clinical course and outcome of novel coronavirus COVID-19 infection in 107 patients discharged from the Wuhan hospital Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease Novel Coronavirus Outbreak Research Team. Semin Thromb Hemost DOI: 10.1055/s-0040-1710006 sha: doc_id: 335516 cord_uid: om7w8y0t nan Thrombocytopenia is reported in 5 to 40% 4, 6, 8, 9 of COVID-19 patients and appears to be associated with more severe disease.
    keywords: coronavirus; covid-19; patients; platelet
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        item: #6204 of 7819
          id: cord-335518-ti889uye
      author: Vianya-Estopa, Marta
       title: Contact lens wear and care in Spain during the COVID-19 pandemic
        date: 2020-11-11
       words: 3963
      flesch: 50
     summary: Importance of rub and rinse in use of multipurpose contact lens solution A comparison of regimen methods for the removal and inactivation of bacteria, fungi and Acanthamoeba from two types of silicone hydrogel lenses Microbial contamination of contact lenses and lens care accessories of soft contact lens wearers (university students) in Hong Kong Microbial flora of tears of orthokeratology patients, and microbial contamination of contact lenses and contact lens accessories Risk factors for moderate and severe microbial keratitis in daily wear contact lens users Water Exposure and the Risk of Contact Lens-Related Disease Compliance behaviour change in contact lens wearers: a randomised controlled trial Number of confirmed coronavirus (COVID-19) cases in Spain between Daily disposable lenses: the better alternative Silicone hydrogel daily disposable benefits: The evidence Could telehealth help eye care practitioners adapt contact lens services during the COVID-19 pandemic? Eye care practitioners should continue to educate contact lens wearers to ensure safe contact lens wear to minimise the chance of developing contact lens related complications during the pandemic.
    keywords: care; contact; covid-19; lens; lenses; pandemic; respondents; wearers
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        item: #6205 of 7819
          id: cord-335539-jc97qxm9
      author: Mahabee-Gittens, E. Melinda
       title: Letter to the Editor Regarding: “An Imperative Need for Research on the Role of Environmental Factors in Transmission of Novel Coronavirus (COVID-19)” —Secondhand and Thirdhand Smoke As Potential Sources of COVID-19
        date: 2020-04-22
       words: 690
      flesch: 46
     summary: Moreover, while emerging evidence suggests younger children do not have as severe COVID-19 related health outcomes as older adults, 3 children are another vulnerable group that may contract the virus and subsequently become vectors of COVID-19, as they have high exposure rates to SHA and SHS. Thus, there is an urgent need to avoid all indoor vaping/smoking to (1) prevent viral spread via exhaled mainstream smoke on which COVID-19 hitches a ride and (2) Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Preliminary evidence that high levels of nicotine on children's hands may contribute to overall tobacco smoke exposure Coronaviruses: an overview of their replication and pathogenesis The Effect of Electronic Cigarette User Modifications and E-liquid Adulteration on the Particle Size Profile of an Aerosolized Product Turbulent Gas Clouds and Respiratory Pathogen Emissions: Potential Implications for Reducing Transmission of COVID-19 Thirdhand smoking: indoor measurements of concentration and sizes of cigarette smoke particles after resuspension Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents
    keywords: covid-19; smoke; transmission
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        item: #6206 of 7819
          id: cord-335549-fzusgbww
      author: Newby, J.
       title: Acute mental health responses during the COVID-19 pandemic in Australia
        date: 2020-05-08
       words: 5980
      flesch: 47
     summary: Comparison between people with and without prior mental health diagnosis 266 People with and without a self-reported history of mental health diagnosis were compared in their severity of 267 COVID-19 fears, mental health, distress, health anxiety, alcohol use, contamination fears, and physical 268 activity. While these 403 symptoms are not necessarily indicative of illness anxiety disorder, high health anxiety is likely to have 404 significant ramifications for health service utilisation.
    keywords: anxiety; covid-19; depression; health; participants; preprint; self; stress
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        item: #6207 of 7819
          id: cord-335550-l7opl6b1
      author: Coronini-Cronberg, Sophie
       title: Health inequalities: the hidden cost of COVID-19 in NHS hospital trusts?
        date: 2020-05-14
       words: 2322
      flesch: 48
     summary: In terms of public messaging, although some channels are beginning to nuance advice, such as 'for lifethreatening emergencies, call 999 for an ambulance', there is an urgent need to communicate clearly and in lay language so that those with emergency health needs should continue to attend Emergency Departments or use other NHS services such as general practices and urgent care centres. However, to minimise COVID-19 infection risk, carbon monxide screening of pregnant women has been temporarily suspended.
    keywords: care; covid-19; health; nhs; patients; services; staff
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        item: #6208 of 7819
          id: cord-335551-1qc5b8a9
      author: Zachariah, Rony
       title: Investing in Operational Research Capacity Building for Front-Line Health Workers Strengthens Countries’ Resilience to Tackling the COVID-19 Pandemic
        date: 2020-07-16
       words: 2781
      flesch: 47
     summary: These findings show that SORT IT has equipped front-line health workers not only with research skills, but also with a skill-set needed to respond to the unprecedented COVID-19 pandemic [7] . It also strengthens human resources for health and the integration of research within health systems.
    keywords: alumni; countries; covid-19; health; research; skills; sort
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        item: #6209 of 7819
          id: cord-335560-fe4ixqdv
      author: Pareek, Manish
       title: Ethnicity and COVID-19: an urgent public health research priority
        date: 2020-04-21
       words: 571
      flesch: 27
     summary: We therefore reviewed published papers and national surveillance reports on notifications and outcomes of COVID-19 to ascertain ethnicity data reporting patterns, associations, and outcomes. More importantly, ethnicity-disaggregated data must occur to permit identification of potential outcome risk factors through adjustment for recognised confounders.
    keywords: covid-19; ethnicity; outcomes
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        item: #6210 of 7819
          id: cord-335576-b34nc3ay
      author: Tsai, Andrew
       title: Impact of tocilizumab administration on mortality in severe COVID-19
        date: 2020-11-05
       words: 2921
      flesch: 38
     summary: A clinical trial evaluating sarilumab in COVID-19 patients was discontinued after failing to meet its primary and key secondary endpoints, and instead revealed negative trends in clinical status of patients who were not mechanically ventilated as baseline 24 . The TOCIVID-19 phase 2 trial Roche rheumatoid arthritis drug fails to help COVID-19 patients in Italian study COVID-19) Treatment Guidelines
    keywords: analysis; covid-19; cytokine; data; patients; propensity; study; tocilizumab
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        item: #6211 of 7819
          id: cord-335578-u8b66oos
      author: Simões e Silva, Ana Cristina
       title: Coronavirus Disease Pandemic Is a Real Challenge for Brazil
        date: 2020-06-05
       words: 1666
      flesch: 49
     summary: The Brazilian scientific community and healthcare workers are working hard to provide support for political health measures to address COVID-19 (15, 16) . However, our capacity to deal with critical cases is limited and very heterogeneous across the 26 states.
    keywords: brazil; cases; covid-19; health; pandemic
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        item: #6212 of 7819
          id: cord-335593-cjb0daps
      author: Romagnolo, Alberto
       title: Neurological comorbidity and severity of COVID-19
        date: 2020-08-04
       words: 3436
      flesch: 33
     summary: A scoping review on the occurrence of neurological diseases in COVID-19 patients reported a prevalence of about 8% [12] . Nevertheless, this review highlighted the methodological heterogeneity in the reviewed papers, which limit a reliable estimation of prevalence of neurological diseases in COVID-19 patients, as well as their association with the infection severity.
    keywords: association; comorbidities; covid-19; data; diseases; infection; patients
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        item: #6213 of 7819
          id: cord-335597-anrzcsrt
      author: None
       title: 44. Jahrestagung der Österreichischen Gesellschaft für Pneumologie
        date: 2020-10-26
       words: 14654
      flesch: 44
     summary: Methods: We performed single cell RNA sequencing on pulmonary arteries isolated from donors and pulmonary hypertension patients. Arteries in pulmonary hypertension patients displayed altered composition of EC population characterized by the diminished presence of one cell cluster.
    keywords: age; analysis; asthma; background; cell; cohort; conclusions; copd; covid-19; data; disease; eine; exercise; function; inflammatory; lung; mean; median; methods; mit; months; mortality; p =; pain; patients; pulmonary; results; score; study; survival; symptoms; therapy; treatment; years
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        item: #6214 of 7819
          id: cord-335610-3v8140b6
      author: Prasanth, D. S. N. B. K.
       title: In silico identification of potential inhibitors from Cinnamon against main protease and spike glycoprotein of SARS CoV-2
        date: 2020-06-22
       words: 5055
      flesch: 41
     summary: (Elfiky & Azzam, 2020; Sinha et al., 2020) . We have taken the PDB ID: 6LZG where spike protein is complexed with ACE2 to investigate the binding affinity of cinnamon derivatives with the complex (Sinha et al., 2020) .
    keywords: binding; compounds; coronavirus; cov-2; covid-19; drug; et al; kcal; mol; protease; protein; sars; spike
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        item: #6215 of 7819
          id: cord-335619-t3yv5y7h
      author: Wang, Song-mi
       title: Screening of SARS-CoV-2 in 299 Hospitalized Children with Hemato-oncological Diseases: A Multicenter Survey in Hubei, China
        date: 2020-08-07
       words: 2429
      flesch: 45
     summary: The proportion of children in COVID-19 patients is significantly lower than that in adults. Four patients (1.3%) had a history of close contact with COVID-19 patients (table 1).
    keywords: children; cov-2; covid-19; infection; patients; sars
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        item: #6216 of 7819
          id: cord-335625-z9ifjsil
      author: Suwanwongse, Kulachanya
       title: Lithium Toxicity in Two Coronavirus Disease 2019 (COVID-19) Patients
        date: 2020-05-31
       words: 1672
      flesch: 45
     summary: Currently, there is no report regarding COVID-19 and lithium toxicity. Herein, we are presenting two patients with COVID-19 who initially presented with signs and symptoms of lithium toxicity.
    keywords: covid-19; lithium; patients; toxicity
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        item: #6217 of 7819
          id: cord-335640-5qwoe4x6
      author: Abdi, Seifollah
       title: COVID-19 sends STEMI to quarantine!?
        date: 2020-05-20
       words: 578
      flesch: 43
     summary: Coronavirus disease 2019 (COVID-19) Situation Report-77 Stent for Life: how this initiative began? Relation of lowering door-to-balloon time and mortality in ST segment elevation myocardial infarction patients undergoing percutaneous coronary intervention Global longitudinal strain by feature tracking for optimized prediction of adverse remodeling after ST-elevation myocardial infarction Multivessel versus culpritonly PCI in STEMI patients with multivessel disease: meta-analysis of randomized controlled trials Predictors of transportation delay in patients with suspected ST-elevation-myocardial infarction in the VIENNA-STEMI network Decline of acute coronary syndrome admissions in Austria since the outbreak of COVID-19: the pandemic response causes cardiac collateral damage Covid-19: Moreover, STEMI patients highly suspicious of COVID-19 should be isolated and screened via laboratory and imaging tests, and the medical staff should use full personal protective equipment (PPE).
    keywords: covid-19; patients
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        item: #6218 of 7819
          id: cord-335642-i0a1si8k
      author: Lozada-Martínez, Ivan
       title: Letter to the Editor: ”Role of the Neurosurgeon in Times of Coronavirus Disease 2019 (COVID-19): The Importance of Focus in Critical Care”
        date: 2020-11-03
       words: 579
      flesch: 26
     summary: This consensus in particular sets a road map for the diagnosis and treatment of patients with COVID-19 in a didactic way, as well as a protocol to be followed in intensive care units to facilitate the patient admission process, triage establishment, isolation management, disinfection of the medical equipment and the environment, waste disposal, highly specialized personal protective equipment use, airway management, and ventilatory support, and finally evaluation of neurologic diseases such as stroke, epileptic status, and neuroimmune and neuromuscular diseases, among others. Some authors who have reported the execution of similar changes point out that these transformations have implied real challenges, since they have needed to be rapidly trained in critical care to be able to establish and provide quality support treatment.
    keywords: care; covid-19
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        item: #6219 of 7819
          id: cord-335648-lbmhprjn
      author: Estrich, Cameron G.
       title: Estimating COVID-19 prevalence and infection control practices among US dentists
        date: 2020-10-15
       words: 4202
      flesch: 43
     summary: Specifically, 0.9% (n ¼ 17) of COVID-19 negative dentists were immunocompromised compared with 6.3% (n ¼ 1) of COVID-19 positive dentists (c 2 P ¼ .02). Coronavirus disease 2019 (COVID-19): people at increased riskdand other people who need to take extra precautions, people at increased risk for severe illness A 4-item measure of depression and anxiety: validation and standardization of the Patient Health Questionnaire-4 (PHQ-4) in the general population Mental health, substance use, and suicidal ideation during the COVID-19 pandemic: United States Kluytmans-van den Bergh MF, Buiting AG, Pas SD, et al. Prevalence and clinical presentation of health care workers with symptoms of coronavirus disease 2019 in 2 Dutch hospitals during an early phase of the pandemic Coronavirus disease 2019 (COVID-2019) infection among health care workers and implications for prevention measures in a tertiary hospital in Wuhan, China Prevalence of COVID-19 infection and outcomes among symptomatic healthcare workers in Centers for Disease and Prevention.
    keywords: control; covid-19; dental; dentists; health; infection; survey
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        item: #6220 of 7819
          id: cord-335653-t3pvm8f9
      author: Escalon, Miguel X.
       title: The immediate impact of the Coronavirus pandemic and resulting adaptations in Physical Medicine and Rehabilitation medical education and practice
        date: 2020-07-23
       words: 4923
      flesch: 45
     summary: key: cord-335653-t3pvm8f9 authors: Escalon, Miguel X.; Raum, George; Tieppo Francio, Vinicius; Eubanks, James E.; Verduzco‐Gutierrez, Monica title: The immediate impact of the Coronavirus pandemic and resulting adaptations in Physical Medicine and Rehabilitation medical education and practice date: 2020-07-23 journal: PM R DOI: 10.1002/pmrj.12455 sha: doc_id: 335653 cord_uid: t3pvm8f9 Since the first reported case of Coronavirus disease (COVID‐19) in the United States in January 2020, substantial changes to medical education have taken place secondary to the demands, chaos, and uncertainty related to the pandemic. The COVID‐19 pandemic has caused PM&R to revisit traditional routines in medical education and adapt to new practices to enhance educational experiences while still maintaining safe social distance between physicians, trainees and patients.
    keywords: covid-19; education; medical; pandemic; physicians; pm&r; residents; students; survey
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        item: #6221 of 7819
          id: cord-335676-7ak53hto
      author: Meftahi, Gholam Hossein
       title: The possible pathophysiology mechanism of cytokine storm in elderly adults with COVID-19 infection: the contribution of “inflame-aging”
        date: 2020-06-11
       words: 8220
      flesch: 40
     summary: The number of immune cells also changed in COVID-19 infection [29, 30] . In healthy adults, due to sufficient vitamin D level, VD can decrease the expression of pro-inflammatory genes in immune cells.
    keywords: ace2; adults; age; aging; cells; covid-19; cytokines; expression; immune; infection; inflammation; lymphocytes; patients; pro; storm
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        item: #6222 of 7819
          id: cord-335704-qejpc4x8
      author: Kuhar, Hannah N.
       title: Otolaryngology in the Time of Corona: Assessing Operative Impact and Risk During the COVID-19 Crisis
        date: 2020-06-02
       words: 4700
      flesch: 36
     summary: This date was selected to capture the earliest phase of COVID-19 preparation in our state, prior to a peak in COVID-19 cases. SUBJECTS AND METHODS: OHNS cases from March 18 to April 8, 2020—the 3 weeks immediately following the Ohio state-mandated suspension of all elective surgery on March 18, 2020—were compared with a 2019 control data set.
    keywords: adult; cases; covid-19; medical; ohns; pediatric; ppe; procedures; study
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        item: #6223 of 7819
          id: cord-335711-15gjv6ae
      author: Viganò, Chiara
       title: COVID-19 in Patients With Inflammatory Bowel Disease: A Single-center Observational Study in Northern Italy
        date: 2020-09-19
       words: 536
      flesch: 45
     summary: Because during the study period virologic testing was available only for inpatients or health care workers besides laboratory confirmed diagnosis, we also included probable cases according to WHO reccomendations (ie, occurrence of an acute respiratory illness AND residence in a high-prevalence area or contact with a COVID-19 case). To ensure validity of the diagnosis of probable cases, one of the following additional criteria was also required: previous influenza vaccination or close contact with a COVID-19 case.
    keywords: covid-19; ibd
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        item: #6224 of 7819
          id: cord-335720-pfo5oup7
      author: Riley, William T
       title: National Institutes of Health social and behavioral research in response to the SARS-CoV2 Pandemic
        date: 2020-07-27
       words: 2869
      flesch: 23
     summary: Digital health care intervention research is needed to determine the role and impact of digital health interventions (e.g., mobile health, telemedicine and telehealth, health information technology, wearable devices, and personalized medicine) during and following the COVID-19 pandemic to ameliorate the secondary health impact. The initial supplemental appropriations from Congress for NIH COVID-19 research (HR6074 and HR748 with combined NIH supplemental appropriations of $1.78 billion) targeted predominately vaccine and therapeutics development and evaluation.
    keywords: care; covid-19; health; interventions; pandemic; research; strategies
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        item: #6225 of 7819
          id: cord-335733-u1g03s2y
      author: Lakshmanan, Hari Hara Sudhan
       title: Design of a Microfluidic Bleeding Chip to Evaluate Antithrombotic Agents for Use in COVID-19 Patients
        date: 2020-08-06
       words: 3493
      flesch: 34
     summary: The velocity of blood in the bleeding channel was recorded by quantifying the rate of blood flow within a graduated polyethylene tubing connected to the distal end of bleeding channel. Our pilot data show a reduction in blood flow velocity as a function of time.
    keywords: bleeding; blood; channel; covid-19; flow; formation; model; patients; plug; thrombosis
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        item: #6226 of 7819
          id: cord-335744-haj5a7tf
      author: Chibbaro, Salvatore
       title: How SARS-CoV-2 is forcing us to reconsider and reorganize our daily neurosurgical practice
        date: 2020-05-13
       words: 1699
      flesch: 30
     summary: One theatre was dedicated to urgent COVID-19 patients, one to urgent non COVID-19 confirmed patients (24/7), and one to 48-hour-deferrable patients (a.k.a. In fact, the geographical characteristics of our region and the strong bond with other units allowed us to transfer critical patients a few kilometers away to Germany, a country with more ICU beds available, and to other centers in our region where elective neurosurgical practice had not been disrupted as much as in Strasbourg.
    keywords: covid-19; crisis; pandemic; patients; practice
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        item: #6227 of 7819
          id: cord-335767-omm04fg5
      author: Raabe, Vanessa N
       title: Importance of Pediatric Inclusion in COVID-19 Therapeutic Trials
        date: 2020-05-27
       words: 1469
      flesch: 24
     summary: We advocate that pediatric patients should be given equal opportunities to enroll in COVID-19 therapeutic clinical trials and outline our rationale for inclusion of children in our hydroxychloroquine treatment trial. We advocate that COVID-19 therapeutic clinical trials should open enrollment to pediatric patients during these early months of the COVID-19 pandemic according to the bioethical principles of autonomy, beneficence, and justice.
    keywords: benefit; children; covid-19; trials
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        item: #6228 of 7819
          id: cord-335768-ry5boej6
      author: Chauhan, Shaylika
       title: Comprehensive review of coronavirus disease 2019 (COVID-19)
        date: 2020-06-01
       words: 4393
      flesch: 49
     summary: Solidarity Trial is an initiative started in March 2020 by the World Health Organization to test drugs and drug combinations including Remdesivir, Chloroquine and hydroxychloroquine combination, Ritonavir/lopinavir and Ritonavir/ lopinavir & interferon-beta against SARS CoV-2. Kai Duan et al. showed that administration of convalescent plasma (CP) obtained from recovered COVID-19 patients who had established humoral immunity against the virus led to COVID-19 patients achieving serum SARS-CoV-2 RNA negativity after CP transfusion, accompanied by an increase of oxygen saturation and lymphocyte counts, and the improvement of liver function and CRP.
    keywords: april; cases; china; coronavirus; cov-2; covid-19; disease; health; patients; people; sars; world
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        item: #6229 of 7819
          id: cord-335792-1yjope1j
      author: Osho, Asishana A.
       title: Veno-venous Extracorporeal Membrane Oxygenation for Respiratory Failure in COVID-19 Patients: Early Experience From a Major Academic Medical Center in North America
        date: 2020-05-22
       words: 2506
      flesch: 37
     summary: These data are still very preliminary for this small cohort and long-term outcomes for COVID-19 VV ECMO patients remain unknown. Given increased care needs, exposure risks to health care staff are higher in ECMO patients, necessitating higher usage of PPE.
    keywords: cannulation; covid-19; ecmo; failure; oxygenation; patients
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        item: #6230 of 7819
          id: cord-335795-hdko0zdw
      author: Wamsley, Christine E
       title: Trends and Challenges of Telehealth in an Academic Institution: The Unforeseen Benefits of the COVID-19 Global Pandemic
        date: 2020-07-22
       words: 5008
      flesch: 44
     summary: The majority of telehealth patients have been between 30 and 79 years old. distribution such that elderly populations comprised a greater proportion of telehealth patients as time passed (ages 60-79 years, Figure 3 ).
    keywords: care; covid-19; pandemic; patient; person; plastic; state; surgery; telehealth; telemedicine; utsw; visits
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        item: #6231 of 7819
          id: cord-335815-51ih0b2y
      author: Lei, Lei
       title: Comparison of Prevalence and Associated Factors of Anxiety and Depression Among People Affected by versus People Unaffected by Quarantine During the COVID-19 Epidemic in Southwestern China
        date: 2020-04-26
       words: 4656
      flesch: 48
     summary: We could not differentiate whether it is one's actual knowledge that was related with anxiety in this study, but Purohit et al. suggested that the perception of one's own knowledge is more strongly related to health anxiety than one's actual knowledge [31] . Comparisons of influenza and SARS in Korea Monitoring of perceptions, anticipated behavioral, and psychological responses related to H5N1 influenza The public's response to severe acute respiratory syndrome in Toronto and the United States Mental health status of people isolated due to Middle East Respiratory Syndrome Factors influencing psychological distress during a disease epidemic: Data from Australia's first outbreak of equine influenza The psychological impact of quarantine and how to reduce it: Rapid review of the evidence Psychological predictors of health anxiety in response to the Zika virus Public health policy and experience of the 2009 H1N1 influenza pandemic in Pune, India A mixed methods approach to creating depression public service announcements by collaborating with people with depressive symptomatology When and how do young people seek professional help for mental health problems Perceived barriers and facilitators to mental health help-seeking in young people: A systematic review Persuasive messages can be more effective when repeated: A comparative survey assessing a message to seek help for depression among Japanese adults Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study Study on psychological behaviors of people in 5 cities of North China under SARS situation All the authors would like to thank the Dr. Long for her enthusiastic support in collection data throughout this investigation.
    keywords: anxiety; covid-19; depression; group; health; level; participants; public
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        item: #6232 of 7819
          id: cord-335838-n1184x8g
      author: Hsu, Caroline M.
       title: COVID-19 in Dialysis Patients: Outlasting and Outsmarting a Pandemic
        date: 2020-10-13
       words: 1566
      flesch: 29
     summary: key: cord-335838-n1184x8g authors: Hsu, Caroline M.; Weiner, Daniel E. title: COVID-19 in Dialysis Patients: Outlasting and Outsmarting a Pandemic date: 2020-10-13 journal: Kidney Int DOI: 10.1016/j.kint.2020.10.005 sha: doc_id: 335838 cord_uid: n1184x8g COVID-19 has affected dialysis patients and dialysis patient care worldwide. In this issue of Kidney International, three reports highlight the disproportionately severe impact of COVID-19 on dialysis patients, noting its high prevalence, particularly among in-center dialysis patients.
    keywords: covid-19; dialysis; kidney; patients
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        item: #6233 of 7819
          id: cord-335855-bifx2nu9
      author: Herrmann, Jacob
       title: Modeling lung perfusion abnormalities to explain early COVID-19 hypoxemia
        date: 2020-09-28
       words: 5616
      flesch: 37
     summary: Modeling lung perfusion abnormalities to explain early COVID-19 hypoxemia date: 2020-09-28 journal: Baseline vascular resistance (R bas ) at each height level (h), relative to baseline total PVR bas , was determined as follows: where Q tot is total pulmonary perfusion (i.e., cardiac output), and Q bas is baseline perfusion at each height level.
    keywords: covid-19; hpv; inj; injured; lung; oxygen; perfusion; shu
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        item: #6234 of 7819
          id: cord-335859-k37jivp6
      author: Wu, Daphne C.
       title: Predictors of self-reported symptoms and testing for COVID-19 in Canada using a nationally representative survey
        date: 2020-10-21
       words: 3113
      flesch: 47
     summary: The strongest predictor of testing was having COVID symptoms among members of the household, of whom about 16.5% were tested, compared to 2.1% among those without COVID symptoms among household members (OR = 6.63, 4.46- A nationally representative survey of Canadians finds that about 8% of adults report that they or someone in their household reported symptoms suggestive of COVID in March 2020. Here, we report on the results of the first nationally-representative poll in Canada of selfreported COVID symptoms conducted by the Angus Reid Forum in early April 2020 covering symptoms reported mostly in March 2020, prior to the peak month of test-reported cases in April.
    keywords: covid; household; sars; survey; symptoms; testing
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        item: #6235 of 7819
          id: cord-335893-9cb8f2ds
      author: Masud, Dhalia
       title: Resuming autologous free tissue transfer for breast reconstruction in the COVID-19 era
        date: 2020-08-28
       words: 1168
      flesch: 45
     summary: key: cord-335893-9cb8f2ds authors: Masud, Dhalia; Sharp, Olivia L.; Rosich-Medina, Anais; Köhler, Guido; Haywood, Richard M. title: Resuming autologous free tissue transfer for breast reconstruction in the COVID-19 era date: 2020-08-28 journal: J Plast Reconstr Aesthet Surg DOI: 10.1016/j.bjps.2020.08.079 sha: doc_id: 335893 cord_uid: 9cb8f2ds The Royal College of Surgeons (RCS) guide to surgical prioritisation during the coronavirus pandemic states that breast reconstruction is Priority level 4 Surgery. In view of the associated increased mortality risk, and potential complications such as return to theatre, autologous free tissue transfer for breast reconstruction was withheld in our unit from the 12th March.
    keywords: breast; covid-19; reconstruction
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        item: #6236 of 7819
          id: cord-335894-6m0nnufu
      author: Ceriello, Antonio
       title: Issues for the management of people with diabetes and COVID-19 in ICU
        date: 2020-07-20
       words: 4150
      flesch: 38
     summary: The measurement of D-dimer is very useful in the prediction of the risk for a thrombotic event and its evaluation has been suggested regarding the management of COVID-19 patients [55, 56] . The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study Coagulation activation in diabetes mellitus: the role of hyperglycaemia and therapeutic prospects Hyperglycemia-induced thrombin formation in diabetes The possible role of oxidative stress Low molecular weight heparin restores antithrombin III activity from hyperglycemia induced alterations Incremental role of glycaemic variability over HbA1c in identifying type 2 diabetic patients with high platelet reactivity undergoing percutaneous coronary intervention Inflammageing and metaflammation: the yin and yang of type 2 diabetes Acute hyperglycaemia: a 'new' risk factor during myocardial infarction Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients Scientific Document Group: 2019 ESC guidelines on diabetes, prediabetes, and cardiovascular diseases developed in collaboration with the EASD Considerations for statin therapy in patients with COVID-19 Tissue specific up regulation of ACE2 in rabbit model of atherosclerosis by atorvastatin: role of epigenetic histone modifications Effect of pravastatin on the frequency of ventilator-associated pneumonia and on intensive care unit mortality: open-label, randomized study Association of elevated plasma interleukin-18 level with increased mortality in a clinical trial of statin treatment for acute respiratory distress syndrome Type 1 diabetes and cardiovascular disease Higher glucose variability in type 1 than in type 2 diabetes patients admitted to the intensive care unit: a retrospective cohort study Searching the reason of a lower aggressiveness of the CoronaVirus disease in Type 1 Diabetes COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options Diabetes and Cardiovascular Disease (D&CVD) EASD Study Group, et al.
    keywords: covid-19; diabetes; disease; glucose; icu; patients; people; risk; type
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        item: #6237 of 7819
          id: cord-335916-fh28qrt7
      author: Liu, Cuiwei
       title: COVID-19 in cancer patients: risk, clinical features, and management
        date: 2020-08-15
       words: 3945
      flesch: 33
     summary: Given that cancer patients without COVID-19 also have a high risk of these complications, attributing these symptoms in COVID-19 cancer patients solely to underlying cancer is difficult. Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in china: summary of a report of 72314 cases from the Chinese center for disease control and prevention Clinical characteristics of 2019 novel coronavirus infection in China Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan Patients with cancer appear more vulnerable to SARS-COV-2: a multicenter study during the COVID-19 outbreak COVID-19 and cancer: what we know so far Nosocomial infections in patients with cancer Selective depletion of regulatory T cell subsets by docetaxel treatment in patients with nonsmall cell lung cancer Features of postoperative immune suppression are reversible with interferon gamma and independent of interleukin-6 pathways Myeloid suppressor cells in cancer and autoimmunity Case fatality rate of cancer patients with COVID-19 in a New York hospital system Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study Clinical characteristics, outcomes, and risk factors for mortality in patients with cancer and COVID-19 in Hubei, China: a multicentre, retrospective, cohort study COVID-19 in patients with thoracic malignancies (TERAVOLT): first results of an international, registry-based, cohort study COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis Outcome of cancer patients infected with COVID-19, including toxicity of cancer treatments COVID-19 in breast cancer patients: a cohort at the institute curie hospitals in the Paris area Clinical characteristics and outcomes of cancer patients With COVID-19 Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Pathological findings of COVID-19 associated with acute respiratory distress syndrome Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Clinical features of 69 cases with coronavirus disease 2019 in Wuhan, China Review of the 2019 novel coronavirus (COVID-19) based on current evidence Relationships among lymphocyte subsets, cytokines, and the pulmonary inflammation Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial Breakthrough: chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Compassionate use of remdesivir for patients with severe covid-19 Therapeutic management of patients with COVID-19: a systematic review Dexamethasone in hospitalized patients with Covid-19 -preliminary report Potential effect of blood purification therapy in reducing cytokine storm as a late complication of critically ill COVID-19 Cytokine storm drugs move from CAR T to COVID-19 Preventing cytokine storm syndrome in COVID-19 using α-1 adrenergic receptor antagonists Seeking and destroying the evils from the inside-translating cancer immunity to fight COVID-19 Cytokine storm and immunomodulatory therapy in COVID-19: role of chloroquine and anti-IL-6 monoclonal antibodies Should we stimulate or suppress immune responses in COVID-19?
    keywords: cancer; covid-19; patients; risk; sars; study; therapy; treatment
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        item: #6238 of 7819
          id: cord-335918-uc225mhn
      author: None
       title: COVID-19 Guidance for Triage of Operations for Thoracic Malignancies: A Consensus Statement from Thoracic Surgery Outcomes Research Network
        date: 2020-04-09
       words: 1487
      flesch: 33
     summary: COVID-19: towards controlling of a pandemic Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia Clinical Characteristics of Coronavirus Disease 2019 in China Characteristics and Outcomes of 21 Critically Ill Patients With COVID-19 in Washington State Minimise nosocomial spread of 2019-nCoV when treating acute respiratory failure Effects of Delayed Surgical Resection on Short-Term and Long-Term Outcomes in Clinical Stage I Non-Small Cell Lung Cancer Defining the Ideal Time Interval Between Planned Induction Therapy and Surgery for Stage IIIA Non-Small Cell Lung Cancer Delay in diagnostic workup and treatment of esophageal cancer Does the timing of esophagectomy after chemoradiation affect outcome? Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China A systematic review and meta-analysis of stereotactic body radiation therapy for colorectal pulmonary metastases Lobectomy versus stereotactic body radiotherapy in healthy patients with stage I lung cancer Survival of Primary SBRT Compared to Surgery for Operable Stage I/II Non-Small Cell Lung Cancer Surveillance versus esophagectomy in esophageal cancer patients with a clinical complete response after induction chemoradiation Outcome of delayed versus timely esophagectomy after chemoradiation for esophageal adenocarcinoma Therefore, cancer patients and the oncology teams that treat them are likely to face difficult decisions between suboptimal management strategies.
    keywords: cancer; covid-19; patients; surgery
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        item: #6239 of 7819
          id: cord-335942-izl6nrsa
      author: Mitra, Manasij
       title: A Study on Challenges to Health Care Delivery Faced by Cancer Patients in India During the COVID-19 Pandemic
        date: 2020-08-24
       words: 2747
      flesch: 38
     summary: WHO Director-General's opening remarks at the media briefing on COVID-19-11 Digital healthcare: the only solution for better healthcare during COVID-19 pandemic? Safeguarding cancer care in a post-COVID-19 world SARS-CoV-2 transmission in patients with cancer at a tertiary care hospital in Wuhan, China Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Risk of COVID-19 for patients with cancer Risk of COVID-19 for patients with cancer Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy Incidence, significance, and persistence of human coronavirus infection in hematopoietic stem cell transplant recipients Managing COVID-19 in the oncology clinic and avoiding the distraction effect Covid-19 and cancer patients: choosing wisely is the key Clinical guide for the management of non-coronavirus patients requiring acute treatment: cancer Effect of the COVID-19 pandemic on cancer treatment and Research Cancer management in India during Covid-19 Provision of cancer care during the COVID-19 pandemic COVID-19 infection in cancer patients: how can oncologists deal with these patients? COVID-19 epidemic: proposed alternatives in the management of digestive cancers: a French Intergroup clinical point of view COVID-19: impact on cancer workforce and delivery of care Advocacy to provide good quality oncology services during the COVID-19 pandemicactions at 3-levels Nutritional counseling for head and neck cancer patients undergoing (chemo) radiotherapy-a prospective randomized trial One-to-one peer support in cancer care: a review of scholarship published between Nutritional aspect of cancer care in medical oncology patients Peer support for cancer patients Advancing psychosocial care in cancer patients Anxiety levels in the cancer patients was assessed through their own perception and not by any standard psychometric assessment technique. This study suggests the need for larger studies on cancer patient care during a pandemic.
    keywords: cancer; care; covid-19; patients; respondents; study; treatment
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        item: #6240 of 7819
          id: cord-335951-m1e9raz3
      author: Rojek, A.
       title: A cross-sectional study of patients presenting for hospital-based screening for COVID-19: risk of disease, and healthcare access preferences.
        date: 2020-04-18
       words: 2497
      flesch: 53
     summary: Failing to do so before patients present to an ED will almost certainly result in EDs becoming overwhelmed, given the anticipated upcoming surge of unwell patients presenting with COVID-19 related respiratory failure. Those patients who do warrant testing for SARS-CoV-2 could then be directed to an appropriate service, with well patients being directed to a community clinic or general practice and unwell patients being referred to ED with their specialised services in critical care.
    keywords: covid-19; patients; preprint; screening
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        item: #6241 of 7819
          id: cord-336000-v88bq4bx
      author: Barco, Stefano
       title: Enoxaparin for primary thromboprophylaxis in ambulatory patients with coronavirus disease-2019 (the OVID study): a structured summary of a study protocol for a randomized controlled trial
        date: 2020-09-09
       words: 20408
      flesch: 38
     summary: OVID may increase the level of safety compared to standard of care for study patients because frequent telephone visits are planned (Day 3, 7, 14, 30, 90) . Source data must be available at the site to document the existence of the study participants and substantiate the integrity of study data collected.
    keywords: acute; analysis; anti; bleeding; center; covid-19; covid-19 patients; data; days; dose; enoxaparin; events; hospitalization; information; investigator; medical; outcome; patients; risk; study; study center; test; thromboprophylaxis; treatment; trial; use; vte
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        item: #6242 of 7819
          id: cord-336004-oz5feg0r
      author: Bui, David P.
       title: Racial and Ethnic Disparities Among COVID-19 Cases in Workplace Outbreaks by Industry Sector — Utah, March 6–June 5, 2020
        date: 2020-08-21
       words: 2447
      flesch: 32
     summary: Sectors are sorted on absolute disparity between the percentage of Hispanic/Latino and nonwhite workers among workplace outbreak cases and the percentage of Hispanic/Latino and nonwhite workers in the overall industry workforce, in descending order. Data on workplace COVID-19 outbreaks occurring during March 6-June 5, 2020, were collected from UDOH's COVID-19 case surveillance system.
    keywords: cases; covid-19; outbreak; sectors; workers; workplace
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        item: #6243 of 7819
          id: cord-336005-nm34bfsl
      author: Mahan, Keenan
       title: Abdominal pain in a patient with COVID-19 infection: A case of multiple thromboemboli
        date: 2020-05-26
       words: 889
      flesch: 36
     summary: key: cord-336005-nm34bfsl authors: Mahan, Keenan; Kabrhel, Christopher; Goldsmith, Andrew J. title: Abdominal pain in a patient with COVID-19 infection: A case of multiple thromboemboli date: 2020-05-26 journal: Am J Emerg Med DOI: 10.1016/j.ajem.2020.05.054 sha: doc_id: 336005 cord_uid: nm34bfsl The novel coronavirus SARS-CoV-2 (COVID-19) pandemic has created diagnostic uncertainty with regards to distinguishing this infection from pulmonary embolism (PE). Although there appears to be an increased incidence of thromboembolic disease in patients with COVID-19 infection, recommendations regarding anticoagulation are lacking.
    keywords: covid-19; patients
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        item: #6244 of 7819
          id: cord-336039-s2alwzov
      author: Lebrasseur, Audrey
       title: Impact of COVID-19 on people with physical disabilities: A rapid review
        date: 2020-11-01
       words: 6144
      flesch: 38
     summary: Experiences in service delivery from South India The Challenge of Managing Parkinson's Disease Patients during the COVID-19 Pandemic The emotional impact of COVID-19 outbreak in amyotrophic lateral sclerosis patients: evaluation of depression, anxiety and interoceptive awareness Wrong study design A Web Based Cross-Sectional Survey Wrong patient population Audiological Needs, Solutions in COVID-19 Awareness, Attitudes, and Actions Related to COVID-19 Among Adults With Chronic Conditions at the Onset of the U.S. Outbreak: A Cross-sectional Survey Wrong patient population Break in the Stroke Chain of Survival due to COVID-19 Call to Action: SARS-CoV-2 and CerebrovAscular DisordErs (CASCADE) Wrong study design CHILDREN WITH SPECIAL HEALTHCARE NEEDS AND COVID-19 RESOURCES.
    keywords: chronic; covid-19; disabilities; health; impact; limit; pandemic; people; stroke; title
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        item: #6245 of 7819
          id: cord-336049-n3swuykg
      author: Ahmed, Mubbasheer
       title: Multisystem inflammatory syndrome in children: A systematic review
        date: 2020-09-04
       words: 5689
      flesch: 41
     summary: key: cord-336049-n3swuykg authors: Ahmed, Mubbasheer; Advani, Shailesh; Moreira, Axel; Zoretic, Sarah; Martinez, John; Chorath, Kevin; Acosta, Sebastian; Naqvi, Rija; Burmeister-Morton, Finn; Burmeister, Fiona; Tarriela, Aina; Petershack, Matthew; Evans, Mary; Hoang, Ansel; Rajasekaran, Karthik; Ahuja, Sunil; Moreira, Alvaro title: Multisystem inflammatory syndrome in children: A systematic review date: 2020-09-04 journal: EClinicalMedicine DOI: 10.1016/j.eclinm.2020.100527 sha: doc_id: 336049 cord_uid: n3swuykg BACKGROUND: Multisystem inflammatory syndrome in children (MIS-C), also known as pediatric inflammatory multisystem syndrome, is a new dangerous childhood disease that is temporally associated with coronavirus disease 2019 (COVID-19). Circulation A case of pediatric multisystem inflammatory syndrome temporally associated with COVID-19 in South Dakota New onset severe right ventricular failure associated with COVID-19 in a young infant without previous heart disease Septic shock presentation in adolescents with COVID-19 Hyperinflammatory shock related to COVID-19 in a patient presenting with multisystem inflammatory syndrome in children: first case from Iran Pediatric inflammatory multisystem syndrome with central nervous system involvement and hypocomplementemia following SARS-COV-2 infection Distinct clinical and immunological features of SARS-COV-2-induced multisystem inflammatory syndrome in children SARS-CoV-2-induced Kawasaki-like hyperinflammatory syndrome: a novel COVID phenotype in children Case report: systemic inflammatory response and fast recovery in a pediatric patient with COVID-19 Cardiac MRI of Children with Multisystem Inflammatory Syndrome (MIS-C) Associated with COVID-19: case Series [published online ahead of print Immune-inflammatory parameters in COVID-19 cases: a systematic review and meta-analysis Neutrophil-to-lymphocyte ratio as an independent risk factor for mortality in hospitalized patients with COVID-19 Clinical value of immune-inflammatory parameters to assess the severity of coronavirus disease 2019 Procalcitonin as a marker of the systemic inflammatory response to infection Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis Interleukin-6 as prognosticator in patients with COVID-19 Outcomes of cardiovascular magnetic resonance imaging in patients recently recovered from coronavirus disease 2019 (COVID-19) High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa A nomogram to predict the risk of unfavourable outcome in COVID-19: a retrospective cohort of 279 hospitalized patients in Paris area Changes in clinical and laboratory features of Kawasaki disease noted over time in Daejeon The riddle of Kawasaki disease Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort Descriptive epidemiology of Kawasaki disease in Japan Pediatric crohn disease and multisystem inflammatory syndrome in children (MIS-C) and COVID-19 treated with infliximab Spectrum of imaging findings on chest radiographs, US, CT, and MRI images in multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 Horizontal transmission of severe acute respiratory syndrome coronavirus 2 to a premature infant: multiple organ injury and association with markers of inflammation Paediatric inflammatory multisystem syndrome: temporally associated with SARS-CoV-2 (PIMS-TS): cardiac features, management and short-term outcomes at a UK tertiary paediatric hospital SARS-CoV-2-related paediatric inflammatory multisystem syndrome, an epidemiological study Cardiac MRI of children with multisystem inflammatory syndrome (MIS-C) associated with COVID-19: case series Multisystem inflammatory syndrome in children associated with severe acute respiratory syndrome coronavirus 2 infection: a multi-institutional study from New York City
    keywords: children; cov-2; covid-19; disease; mis; multisystem; patients; review; sars; syndrome
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        item: #6246 of 7819
          id: cord-336053-cjq7szcn
      author: Mottola, Filiberto Fausto
       title: Cardiovascular System in COVID-19: Simply a Viewer or a Leading Actor?
        date: 2020-08-27
       words: 5641
      flesch: 37
     summary: Patients: Awareness of an Increased Prevalence Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Sanchis-Gomar, F. Cardiac troponin I in patients with coronavirus disease 2019 (COVID-19): Evidence from a meta-analysis Cardiovascular Implications of Fatal Outcomes of Patients with Coronavirus Disease 2019 (COVID-19) Clinical features of patients infected with 2019 novel coronavirus in Association of Coronavirus Disease 2019 (COVID-19) with Myocardial Injury and Mortality SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS Acute myocarditis associated with novel Middle East respiratory syndrome coronavirus The Variety of Cardiovascular Presentations of COVID-19 Coinvolgimento cardiaco in un paziente con malattia coronavirus 2019 (COVID-19) Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems during the COVID-19 Pandemic Influenza epidemics and acute respiratory disease activity are associated with a surge in autopsy-confirmed coronary heart disease death: Results from 8 years of autopsies in 34 892 subjects Seasonal Influenza Infections and Cardiovascular Disease Mortality COVID-19 and the cardiovascular system Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study SARS-CoV-2: A potential novel etiology of fulminant myocarditis Characteristics and Outcomes of Recipients of Heart Transplant with Coronavirus Disease European Heart Rhythm Association (EHRA) consensus document on management of arrhythmias and cardiac electronic devices in the critically ill and post-surgery patient, endorsed by Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Cardiac Arrhythmia Society of Southern Africa (CASSA), and Latin American Heart Rhythm Society (LAHRS) Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy Systemic inflammation and arrhythmic risk: Lessons from rheumatoid arthritis Cardioimmunology of arrhythmias: The role of autoimmune and inflammatory cardiac channelopathies Cardiotoxicity of antimalarial drugs Drug-induced ventricular tachycardia Heart conduction disorders in long-term treatment with chloroquine. While ECG monitoring is always available for COVID-19 patients admitted to ICU, in patients hospitalized in non-intensive rooms, clinicians should monitor QT-intervals according to the risk factors.
    keywords: acute; cardiac; coronavirus; covid-19; damage; disease; heart; increase; infection; patients; risk; sars
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        item: #6247 of 7819
          id: cord-336064-8b5cvll7
      author: Bolaño-Ortiz, Tomás R.
       title: Spread of SARS-CoV-2 through Latin America and the Caribbean region: a look from its economic conditions, climate and air pollution indicators
        date: 2020-07-15
       words: 4611
      flesch: 43
     summary: We have found that the incidence rate of COVID-19 cases shows a negative correlation with wind speed, whereas with air pollution indicators, there was a positive correlation in several LAC cities. (2020) analyzed the global correlation of COVID-19 cases and deaths with the gross domestic product (GDP) per capita.
    keywords: air; cases; cities; covid-19; et al; lac; new; temperature
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        item: #6248 of 7819
          id: cord-336071-t7c0drft
      author: Chiyomaru, Katsumi
       title: Global COVID-19 transmission rate is influenced by precipitation seasonality and the speed of climate temperature warming
        date: 2020-04-14
       words: 1622
      flesch: 35
     summary: key: cord-336071-t7c0drft authors: Chiyomaru, Katsumi; Takemoto, Kazuhiro title: Global COVID-19 transmission rate is influenced by precipitation seasonality and the speed of climate temperature warming date: 2020-04-14 journal: nan DOI: 10.1101/2020.04.10.20060459 sha: doc_id: 336071 cord_uid: t7c0drft The novel coronavirus disease 2019 (COVID-19) became a rapidly spreading worldwide epidemic; thus, it is a global priority to reduce the speed of the epidemic spreading. An investigation of 346 transmission control measures during the first 50 days of the COVID-19 epidemic Epidemic curves made 349 easy using the R package incidence Global COVID-19 transmission rate is influenced by 352 precipitation seasonality and the speed of climate temperature warming Very high resolution 355 interpolated climate surfaces for global land areas Macroecological 358 trends in nestedness and modularity of seed-dispersal networks: human impact matters The 361 influence of late Quaternary climate-change velocity on species endemism 364 Population Density, Revision 11 The 366 human footprint and the last of the wild Gridded global datasets for Gross Domestic 369 Product and Human Development Index over 1990-2015.
    keywords: covid-19; growth; rate; temperature
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        item: #6249 of 7819
          id: cord-336076-go5tk6ni
      author: Burke, Rachel M.
       title: Symptom Profiles of a Convenience Sample of Patients with COVID-19 — United States, January–April 2020
        date: 2020-07-17
       words: 2911
      flesch: 45
     summary: To better understand symptom profiles of patients with laboratory-confirmed COVID-19 in the United States, CDC used an optional questionnaire to collect detailed information on a convenience sample of COVID-19 patients from participating states. To better understand symptom profiles of patients with laboratory-confirmed COVID-19 in the United States, CDC used an optional questionnaire to collect detailed information on a convenience sample of COVID-19 patients from participating states.
    keywords: covid-19; health; patients; response; symptoms; team
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        item: #6250 of 7819
          id: cord-336115-7ykvl3u6
      author: Binns, Colin
       title: The COVID-19 Pandemic: Public Health and Epidemiology
        date: 2020-05-19
       words: 3560
      flesch: 55
     summary: At the present time, COVID-19 disease is diagnosed by detecting the virus in throat and nasal swabs in patients who have symptoms of an upper respiratory tract infection who have been in a region with disease transmission. COVID-19 is the latest in a continuing series of infectious disease epidemics in the history of the human race.
    keywords: cases; covid-19; disease; epidemic; health; public; symptoms; transmission
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        item: #6251 of 7819
          id: cord-336133-kpzjrj15
      author: Choi, Kristen R.
       title: Nursing and the novel coronavirus: Risks and responsibilities in a global outbreak
        date: 2020-04-15
       words: 674
      flesch: 47
     summary: Individuals who have preexisting health vulnerabilities are at greatest risk for COVID-19 complications or mortality and nursing resources are critical to managing this population. National Nurses United Response to COVID-19 How to face the novel coronavirus infection during the 2019-2020 epidemic: The experience of Sichuan Provincial People's Hospital Another decade, another coronavirus Effects of misleading media coverage on public health crisis: A case of the 2019 novel coronavirus outbreak in China Coronavirus disease (COVID-19) outbreak A novel coronavirus from patients with pneumonia in China
    keywords: coronavirus; covid-19
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        item: #6252 of 7819
          id: cord-336148-50ovfwvo
      author: Arnold, D. T.
       title: Blood parameters measured on admission as predictors of outcome for COVID-19; a prospective UK cohort study
        date: 2020-06-29
       words: 3874
      flesch: 43
     summary: A meta-analysis of adjusted risk estimates Prognostic value of NT-proBNP in patients with severe COVID-19 Systematic assessment of venous thromboembolism in COVID-19 patients receiving thromboprophylaxis: incidence and role of D-dimer as predictive factors D-dimer levels on admission to predict in-hospital mortality in patients with Covid-19 Clinical course of 2019 novel coronavirus disease (COVID-19) in individuals present during the outbreak on the Diamond Princess cruise ship Association between chest CT features and clinical course of Coronavirus Disease Early decrease in blood platelet count is associated with poor prognosis in COVID-19 patients-indications for predictive, preventive, and personalized medical approach Kinetic and reversibility of mechanical ventilation-associated pulmonary and systemic inflammatory response in patients with acute lung injury Profiling serum cytokines in COVID-19 patients reveals IL-6 Admission blood biomarkers have only moderate predictive value for predicting COVID-19 outcomes, while simple clinical features such as age and NEWS score outperform many biomarkers.
    keywords: admission; biomarkers; blood; care; covid-19; license; medrxiv; patients; preprint
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        item: #6253 of 7819
          id: cord-336163-7xqmuoye
      author: van Dongen, Christel MP
       title: Unusually Rapid Development of Pulmonary Hypertension and Right Ventricular Failure after COVID-19 Pneumonia
        date: 2020-06-17
       words: 1222
      flesch: 30
     summary: Pulmonary hypertension can develop unusually rapidly following COVID-19 pneumonia and probably results from progressive pulmonary interstitial and microvascular abnormalities due to COVID-19. A 60-year-old man, with a medical history of minor myocardial infarction with no abnormalities on coronary angiography 7 years earlier, was admitted to our intensive care unit (ICU) for severe COVID-19 pneumonia in April 2020.
    keywords: covid-19; disease; pneumonia
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        item: #6254 of 7819
          id: cord-336172-nzsa7qhb
      author: Looi, Jeffrey CL
       title: To tele- or not to telehealth? Ongoing COVID-19 challenges for private psychiatry in Australia
        date: 2020-08-26
       words: 2012
      flesch: 35
     summary: However, the retention of COVID-19 MBS telehealth items is needed for ongoing flexible and comprehensive private practice psychiatry. For private psychiatric patients requiring inpatient care, there are no MBS telehealth items for psychiatric consultation.
    keywords: care; covid-19; patients; telehealth; telepsychiatry
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        item: #6255 of 7819
          id: cord-336175-khkkxcwr
      author: Ha, Kyoo-Man
       title: The principle of distance during COVID-19 outbreak in Korea
        date: 2020-07-27
       words: 1578
      flesch: 50
     summary: Nations that have not faced the full extent of the coronavirus threat yet may enforce the golden rule of social distance from the outset. key: cord-336175-khkkxcwr authors: Ha, Kyoo-Man title: The principle of distance during COVID-19 outbreak in Korea date: 2020-07-27 journal: Int Microbiol DOI: 10.1007/s10123-020-00138-w sha: doc_id: 336175 cord_uid: khkkxcwr
    keywords: covid-19; distance; infection; outbreak
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        item: #6256 of 7819
          id: cord-336177-p7b7yw28
      author: Selvi, Valeria
       title: Convalescent Plasma: A Challenging Tool to Treat COVID-19 Patients—A Lesson from the Past and New Perspectives
        date: 2020-09-22
       words: 5464
      flesch: 40
     summary: WHO Pandemia WHO Director-General's opening remarks at the media briefing on COVID-19 -11 Perspectives on therapeutic neutralizing antibodies against the Novel Coronavirus SARS-CoV-2 Immunoglobulins or convalescent plasma to tackle COVID-19: buying time to save livescurrent situation and perspectives Convalescent plasma as a potential therapy for COVID-19 Blood transfusion during the COVID-19 outbreak A novel treatment approach to the novel coronavirus: an argument for the use of therapeutic plasma exchange for fulminant COVID-19 Treatment of COVID-19: old tricks for new challenges The convalescent sera option for containing COVID-19 Passive immunity in prevention and treatment of infectious diseases Convalescent plasma: new evidence for an old therapeutic tool? Points to consider in the preparation and transfusion of COVID-19 convalescent plasma Ebola virus convalescent blood products: where we are now and where we may need to go Evaluation of convalescent whole blood for treating Ebola virus disease in Convalescent plasma in Covid-19: possible mechanisms of action An augmented passive immune therapy to treat fulminant bacterial infections Position paper on use of convalescent plasma, serum or immune globulin concentrates as an element in response to an emerging virus Meta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment? Efficacy of immune plasma in treatment of Argentine haemorrhagic fever and association between treatment and a late neurological syndrome Use of convalescent plasma therapy in SARS patients in Hong Kong Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection Hyperimmune IV immunoglobulin Treatment The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysis Treatment of Ebola hemorrhagic fever with blood transfusions from convalescent patients Efficacy of convalescent plasma in relation to dose of Ebola virus antibodies Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience Risks and side effects of therapy with plasma and plasma fractions Treatment for emerging viruses: convalescent plasma and COVID-19 Safety update: COVID-19 convalescent plasma in 20,000 hospitalized patients Recommendations for investigational COVID-19 convalescent plasma-Food and Drug Administration Convalescent plasma is a clutch at straws in COVID-19 management! However, convalescent plasma was demonstrated to be associated with antiviral activity in patients with COVID-19 (convalescent plasma treatment was associated with higher rates of negative SARS-CoV-2 viral PCR results from nasopharyngeal swabs at 24, 48, and 72 hours); a statistically significant improvement was noted for the convalescent plasma treatment group compared to controls in the subgroup of patients without life-threatening COVID-19 (91% improvement in the plasma group compared to 68% in the control arm).
    keywords: blood; convalescent; convalescent plasma; covid-19; patients; plasma; sars; therapy; treatment; use
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        item: #6257 of 7819
          id: cord-336178-k8za0doe
      author: Afshar, Parnian
       title: COVID-CAPS: A Capsule Network-based Framework for Identification of COVID-19 cases from X-ray Images
        date: 2020-09-16
       words: 4234
      flesch: 50
     summary: Computed tomography (CT) scans and X-ray images, on the other hand, reveal specific manifestations associated with this disease. Our results based on a dataset of X-ray images show that COVID-CAPS has advantage over previous CNN-based models.
    keywords: caps; capsule; covid; covid-19; dataset; images; ray
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        item: #6258 of 7819
          id: cord-336194-5v395xae
      author: Darafsheh, Arash
       title: Mitigating disruptions, and scalability of radiation oncology physics work during the COVID‐19 pandemic
        date: 2020-05-20
       words: 3045
      flesch: 40
     summary: : scope of practice for clinical medical physics A special report of current state of the medical physicist workforce -results of the 2012 ASTRO Comprehensive Workforce Study A program to train medical physicists for direct patient care responsibilities The solo practice of medical physics in radiation oncology Clinical medical physicists play a vital role in ensuring safe and effective delivery of radiotherapy in a cancer clinic.
    keywords: cancer; covid-19; medical; oncology; pandemic; patients; physics; radiation; radiotherapy; team
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        item: #6259 of 7819
          id: cord-336204-zz99v3ht
      author: Seo, Wan Seok
       title: Yeungnam University type drive-through (YU-Thru) coronavirus disease 2019 (COVID-19) screening system: a rapid and safe screening system
        date: 2020-09-18
       words: 2989
      flesch: 55
     summary: In addition, under the CSS procedures, there was a possibility of medical staff being infected by confirmed COVID-19 patients. In order to contain the spread of infectious diseases, prompt detection of as many cases as possible through active laboratory testing, active quarantine of confirmed patients, systematic classification of patients according to the degree of symptoms, and initiation of step-by-step treatment strategies according to severity are crucial.
    keywords: covid-19; css; number; screening; staff; system
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        item: #6260 of 7819
          id: cord-336217-t4wm1k52
      author: Mehta, Bella
       title: Geographical variations in COVID-19 Perceptions and Patient Management: A National Survey of Rheumatologists
        date: 2020-07-06
       words: 2894
      flesch: 42
     summary: The guidelines, in addition to most experts, recommend that rheumatic disease patients on standing immunosuppressive medications should be maintained on their long-term therapy and only withhold the drug/s if they contract COVID-19 infection. In this survey of US rheumatologists, we found significant variations in perceptions regarding risk of COVID-19 infection.
    keywords: covid-19; patients; rheumatologists; risk; survey
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        item: #6261 of 7819
          id: cord-336252-e92omqyr
      author: Chen, Tracy Yixin
       title: COVID‐19 pneumonia in kidney transplant recipients: Focus on immunosuppression management
        date: 2020-07-06
       words: 1884
      flesch: 26
     summary: Initial report from the US epicenter A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia Covid-19 and kidney transplantation The COVID-19 Pandemic in the US Effectiveness and safety of two different antithymocyte globulins used in induction therapy in kidney transplant recipients: a single-center experience Polyclonal anti T-lymphocyte antibody therapy monitoring in kidney transplant recipients: comparison of CD3+ T cell and total lymphocyte counts Monitoring of CD3(+) T-cell count in patients receiving antithymocyte globulin induction after cadaveric renal transplantation Effect of rabbit antithymocyte globulin on acute and chronic active antibody-mediated rejection after kidney transplantation Direct antiviral mechanisms of interferon-gamma Immune responses in COVID-19 and potential vaccines: lessons learned from SARS and MERS epidemic Cyclosporin A and tacrolimus reduce T-cell polyfunctionality but not interferon-γ responses directed at cytomegalovirus Pathogen-specific T cell polyfunctionality is a correlate of T cell efficacy and immune protection T cell exhaustion during persistent viral infections Reduction and Functional Exhaustion of T Cells in Patients With Coronavirus Disease 2019 (COVID-19) Fighting COVID-19 exhausts T cells Dysregulation of Immune Response in Patients With Coronavirus Interferon-mediated immunopathological events are associated with atypical innate and adaptive immune responses in patients with severe acute respiratory syndrome Immunosuppression for hyperinflammation in COVID-19: a double-edged sword?
    keywords: covid-19; disease; kidney; patients; pneumonia; transplant
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        item: #6262 of 7819
          id: cord-336257-f6yglaz8
      author: Forte, Giuseppe
       title: The Enemy Which Sealed the World: Effects of COVID-19 Diffusion on the Psychological State of the Italian Population
        date: 2020-06-10
       words: 4358
      flesch: 43
     summary: Among all respondents, only 9 (0.4%) were infected by the COVID-19, and 40 (1.7%) were sure that they had had close contacts with individuals suspected of COVID-19 infection (see Table 1 ). Of the overall sample, 112 respondents (4.9%) and 177 (7.7%) respectively knew people dead and patients in intensive care units (ICU) because of COVID-19 infection.
    keywords: anxiety; covid-19; data; people; population; results; study; symptomatology
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        item: #6263 of 7819
          id: cord-336258-dxps48bo
      author: Lee, Anne W.M.
       title: Advocacy to provide good quality oncology services during the COVID-19 pandemic – Actions at 3-Levels
        date: 2020-05-08
       words: 2150
      flesch: 44
     summary: Not only is the cumulated number of COVID-19 patients substantially lower in other provinces, the drop in new cases occurred much earlier (Fig. 1B) . diagnostic PCR test is extensively provided to screen all high-risk cohorts and patients requiring admission As a designated hospital responsible for convalescent care of COVID-19 patients and screening of foreign citizens/visitors, special measures are implemented to ensure safety for all staffs and patients, while continuing to provide essential clinical services as far as we can.
    keywords: covid-19; hospital; patients; services; staffs; treatment
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        item: #6264 of 7819
          id: cord-336268-azgswke8
      author: Porcel-Vazquez, Juan A.
       title: Usefulness of PCR Screening in the Initial Triage of Trauma Patients During COVID-19 Pandemic
        date: 2020-07-13
       words: 3452
      flesch: 43
     summary: Initial triage to perform quantitative reverse transcription polymerase chain reaction (RT-qPCR) based on symptoms of respiratory disease and chest x-ray and/or based on epidemiological criteria in the emergency department (ED) may be not enough to avoid nosocomial infection or unprotected hospitalization and surgery for health care workers due to the significant incidence of asymptomatic COVID-19 patients. Unfortunately, a high proportion of COVID-19 patients (56%) present no or mild symptoms, 8 thus hindering their management.
    keywords: covid-19; health; infection; patients; period; symptoms
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        item: #6265 of 7819
          id: cord-336283-3q0ujnjq
      author: Sanderson, William C.
       title: The Nature and Treatment of Pandemic-Related Psychological Distress
        date: 2020-06-27
       words: 9298
      flesch: 39
     summary: Moreover, many individuals may attempt to cope with these negative psychological effects in unhelpful ways (e.g., alcohol/ substance use) that can actually result in an increased susceptibility to COVID-19 (Da et al. 2020; Volkow 2020) . Many individuals, particularly younger generations, are Table 1
    keywords: covid; covid-19; crisis; distress; fear; health; help; home; increase; individuals; loss; pandemic; result; strategies; time
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        item: #6266 of 7819
          id: cord-336298-odl1nv4i
      author: Wang, Xiaoqiang
       title: Effects of Chinese strategies for controlling the diffusion and deterioration of novel coronavirus-infected pneumonia in China
        date: 2020-03-12
       words: 2020
      flesch: 55
     summary: By implementing multiple Chinese strategies, the growth speed of confirmed patients reached Speedmax and began to decline within 14 days in almost all areas of mainland China. https://doi.org/10.1101/2020.03.10.20032755 doi: medRxiv preprint For COVID-19 data, we collected the number of cumulative confirmed patients from January 21, 2020 to February 23, 2020 because almost all areas in China began to report confirmed cases from January 21, 2020, and the growth speed reached zero around most areas except Hubei before February 23, 2020.
    keywords: china; covid-19; medrxiv; preprint
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        item: #6267 of 7819
          id: cord-336320-riedcgus
      author: Pacheco, J.
       title: Gender disparities in access to care for time-sensitive conditions during COVID-19 pandemic in Chile
        date: 2020-09-11
       words: 4362
      flesch: 46
     summary: 11 To our knowledge, a single research explored access differences in cancer care by sex during a pandemic. https://doi.org/10.1101/2020.09.11.20192880 doi: medRxiv preprint In our model, we confirmed a larger reduction for cancer conditions (IRR 0·56; 95% CI 0·50-0·63) compared to the cardiovascular events (IRR 0·64; 95% CI 0·62-0·66).
    keywords: access; cancer; covid-19; gender; pandemic; preprint; women
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        item: #6268 of 7819
          id: cord-336373-xb3jrg75
      author: Vivas, Esther X.
       title: COVID19 and Otology/Neurotology
        date: 2020-08-22
       words: 1982
      flesch: 45
     summary: In general, it is safe to say that while N95s have been used extensively, the role of CAPR and PAPR is limited for routine otologic and neurotologic procedures, but may be necessary on COVID-19 positive patients. Examples of good telehealth candidates include cochlear implant follow ups, tinnitus or hyperacusis counseling and vestibular patients, such as those with established Meniere's disease and lack of middle ear pathology.
    keywords: changes; covid-19; patients
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        item: #6269 of 7819
          id: cord-336390-ptnpgh3j
      author: Passamonti, Francesco
       title: Clinical characteristics and risk factors associated with COVID-19 severity in patients with haematological malignancies in Italy: a retrospective, multicentre, cohort study
        date: 2020-08-13
       words: 4679
      flesch: 32
     summary: Raccomandazioni per il corretto prelievo, conservazione e analisi sul tampone oro/rino-faringeo per la diagnosi di COVID-19 Sorveglianza Integrata COVID-19 in Italia COVID-19 in solid organ transplant recipients: initial report from the US epicenter Characteristics and outcomes of recipients of heart transplant with coronavirus disease 2019 Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 Observational study of hydroxychloroquine in hospitalized patients with Covid-19 Effective treatment of severe COVID-19 patients with tocilizumab The role of JAK2 inhibitors in MPNs 7 years after approval Outcomes of COVID-19 in patients with CLL: a multicenter, international experience The study is supported by the charity Associazione italiana contro le leucemie, linfomi e mieloma-Varese Onlus. As of Aug 2, 2020, there have been more than 18·1 million cases of SARS-CoV-2 infection worldwide, with comorbidities shown to affect disease severity and patient outcomes.
    keywords: cohort; covid-19; data; disease; malignancies; malignancy; mortality; non; patients; population; study; survival
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        item: #6270 of 7819
          id: cord-336395-v157jzvv
      author: Battaglini, Denise
       title: Chest physiotherapy: an important adjuvant in critically ill mechanically ventilated patients with COVID-19
        date: 2020-08-17
       words: 7012
      flesch: 29
     summary: Recent manuscripts on respiratory physiotherapy in COVID-19 patients provided general recommendations but did not focus on critically ill COVID-19 cases (Lazzeri et al., 2020; Thomas et al., 2020) . Sputum production was reported in about 34% of COVID-19 patients (Guan et al., 2020) , thus suggesting that, by promoting mucus clearance during mechanical ventilation, early physiotherapy interventions (such as subglottic secretion drainage, postural hygiene, and ventilator hyperinflation) may produce beneficial effects in this new critically ill population (Thomas et al., 2020) .
    keywords: chest; covid-19; et al; extubation; icu; lung; patients; physiotherapy; position; pressure; risk; thomas; ventilator
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        item: #6271 of 7819
          id: cord-336397-mgrezzmw
      author: Habib, Yasir
       title: Time–frequency co-movement between COVID-19, crude oil prices, and atmospheric CO(2) emissions: Fresh global insights from partial and multiple coherence approach
        date: 2020-10-11
       words: 6589
      flesch: 48
     summary: Adopting the Torrence and Webster (1999) framework to formulate the mathematical equation for wavelet transforms coherence is infra; R is viewed as a smoothing operator, with the squared coefficient of wavelet transform coherence (WTC) range from: (4) W xy (m, n) = W x (m, n)W * y (m, n), (6) 0 This paper employs the comprehensive wavelet coherence analysis tools, including wavelet transform coherence as well as continuous, partial and multiple wavelet coherence, to enclose the association and co-movement between global daily new infected and confirmed cases of COVID-19, global daily CO 2 emissions, and daily crude oil prices across time scales.
    keywords: coherence; covid-19; emissions; figure; frequency; oil; oil prices; prices; series; time; transform; wavelet; wavelet coherence
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        item: #6272 of 7819
          id: cord-336432-tu00gffr
      author: Wang, Zhiyu
       title: Small molecule therapeutics for COVID-19: repurposing of inhaled furosemide
        date: 2020-07-07
       words: 6618
      flesch: 40
     summary: We investigated if furosemide inhibits the production of pro-inflammatory cytokines (M1) or promotes the secretion of anti-inflammatory cytokines (M2) using various macrophage cell lines including RAW264.7, THP-1 and SIM-A9. In this study, a library of small molecules endogenous to the human body was assembled, subjected to in silico molecular docking simulations and a focused in vitro screen to identify anti-pro-inflammatory activity via interleukin inhibition.
    keywords: acid; cells; covid-19; cytokines; docking; furosemide; haa; il-6; ligand; lps; pro; protein; tnf
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        item: #6273 of 7819
          id: cord-336438-mlgxiyur
      author: Huda, Farhanul
       title: Covid-19 and surgery: Challenging issues in the face of new normal – A narrative review
        date: 2020-10-23
       words: 4931
      flesch: 46
     summary: It's bad for you and for hospitals American College of Surgeons, COVID-19 Guidelines for triage of cancer surgery patients Guiding Principles for Cancer Surgery during the COVID-19 Pandemic Emergency surgery in suspected COVID-19 patients with acute abdomen: case series and perspectives Emergency Surgery in Suspected COVID-19 Patients With Acute Abdomen: Case Series and Perspectives National Health Commission of the People's Republic of China, Diagnosis and treatment of novel coronavirus pneumonia COVID-19 and the Risk to Health Care Workers: A Case Report AMASI (Association of Minimal Access Surgeons of India) Guidelines for Conducting Minimal Access Surgery during COVID-19 Pandemic SAGES and EAES recommendations for minimally invasive surgery during COVID-19 pandemic Guiding airway management and personal protective equipment for COVID-19 intubation teams Appropriate Use of Laparoscopy over Open Procedures in the Current COVID-19-19 Climate? It should retrieve data on the availability of resources and their utilization, COVID-19 awareness data amongst HCWs and community, management of COVID-19 patients, and errors during management, complications, and the means to rectify those.
    keywords: care; consent; covid-19; hospital; infection; pandemic; patients; risk; surgery
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        item: #6274 of 7819
          id: cord-336447-hpnkou41
      author: Pitlik, Silvio Daniel
       title: COVID-19 Compared to Other Pandemic Diseases
        date: 2020-07-31
       words: 6150
      flesch: 44
     summary: 87, 88 Readers can visit these sites to access updates regarding ongoing developments related to COVID-19 vaccines and treatments. Excess mortality estimation during the COVID-19 pandemic: preliminary data from Portugal Diagnostic performance of COVID-19 serology assays Cholera and the water supply in the South districts of London UCLA Department of Epidemiology, Fielding School of Public Health New insights on the emergence of cholera in Latin America during 1991: the Peruvian experience Impact of complete lockdown on total infection and death rates: a hierarchical cluster analysis The Jenner Society and the Edward Jenner Museum: tributes to a physicianscientist Smallpox vaccines for biodefense Draft landscape of COVID-19 candidate vaccines The race for coronavirus vaccines: a graphical guide The COVID-19 vaccine development landscape The SARS-CoV-2 vaccine pipeline: an overview Remdesivir for the treatment of COVID-19 -preliminary report Deployment of convalescent plasma for the prevention and treatment of COVID-19 Economics in the Age of COVID-19 The economic impact of COVID-19 COVID-19: in the footsteps of Ernest Shackleton Coronavirus drug and treatment tracker Coronavirus vaccine tracker.
    keywords: cases; coronavirus; cov-2; covid-19; disease; history; human; new; number; pandemic; sars; vaccine; virus; viruses
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        item: #6275 of 7819
          id: cord-336453-cbq0ui4p
      author: Machitori, Akihiro
       title: Computed tomography surveillance helps tracking COVID-19 outbreak
        date: 2020-08-07
       words: 3807
      flesch: 48
     summary: We call the program 'Computed Tomography Imaging Surveillance of Viral Pneumonia,' (hereinafter referred to as CT surveillance) as it is designed to identify suspected or confirmed COVID-19 carriers with CT findings that are similar to those of COVID-19 pneumonia. We also analyzed CT findings, age distribution, gender differences, and clinical diagnoses obtained by CT surveillance.
    keywords: covid-19; findings; number; patients; pcr; surveillance
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        item: #6276 of 7819
          id: cord-336455-dmaatzjc
      author: Kooraki, Soheil
       title: Re: Ventilation-perfusion Scans During the Coronavirus (COVID-19) Outbreak
        date: 2020-04-10
       words: 331
      flesch: 26
     summary: All the personnel should follow the recommended PPE for COVID-19 pneumonia, which includes N95 respirator or higher, medical mask, apron, gown, gloves and eye protection with googles. [5] In summary, limiting the acquisition of pulmonary V/Q scan, elimination of the ventilation phase of the scan, appropriate use of PPE by all department staff, the use of negative airway pressure in the procedure room and thorough decontamination of the procedure room after each V/Q scan can help the nuclear medicine department to minimize the impact of COVID-19 pandemic on the staff, the equipment and the healthcare facility.
    keywords: covid-19; procedure
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        item: #6277 of 7819
          id: cord-336467-w528t92h
      author: Anderson, Diana C.
       title: Nursing Home Design and COVID-19: Balancing Infection Control, Quality of Life, and Resilience
        date: 2020-10-31
       words: 4090
      flesch: 38
     summary: A Person-Centred Framework for Assessment and Support Planning Disaster Preparedness for Seniors: A Comprehensive Guide for Healthcare Professionals Resilient urban form: A conceptual framework Geographical Gerontology: Perspectives, Concepts, Approaches The meaning of aging in place to older people The importance of place for older people moving into care homes Housing-Choicesfor-Older-People-in-Ireland-Time-for-Action-1.pdf Nursing homes or besieged castles: COVID-19 in northern Italy A 10 step framework to implement integrated care for older persons Talking while walking: An investigation of perceived neighbourhood walkability and its implications for the social life of older people The green house model of nursing home care in design and implementation Activity-friendly neighbourhoods can benefit noncommunicable and infectious diseases Planning and designing for pedestrians using mobility equipment COVID-19: Keeping things moving Adverse effects of outdoor pollution in the elderly Association between short-term exposure to air pollution and COVID-19 infection: Evidence from China Characteristics of U.S. nursing homes with COVID-19 cases How can pandemic spreads be contained in care homes? Post-occupancy evaluation of a transformed nursing home: The first four Green House� settings Effect of design interventions on a dementia care setting Small-scale homelike care in nursing homes Sage Advocacy Submission to COVID-19 Nursing Home Expert Panel sage advocacy How can pandemic spreads be contained in care homes Guidelines for preventing respiratory illness in older adults aged 60 years and above living in long-term care: A rapid review of clinical practice guidelines. In this context, the quality of life issues discussed in the previous section have implications for resilience, yet very little attention has been paid to these issues in relation to nursing home design.
    keywords: care; covid-19; design; home; infection; life; nursing; quality; residents
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        item: #6278 of 7819
          id: cord-336481-vrnxu217
      author: Bonifácio, Lívia Pimenta
       title: Are SARS-CoV-2 reinfection and Covid-19 recurrence possible? a case report from Brazil
        date: 2020-09-18
       words: 1523
      flesch: 44
     summary: Although theoretically possible, the fact that she fell ill for the second time about a week after being home exposed to confirmed Covid-19 cases makes this explanation very unlikely. On June 21, two family members develop flu-like symptoms and were lately confirmed as Covid-19 cases by RT-PCR.
    keywords: cov-2; covid-19; sars; symptoms
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        item: #6279 of 7819
          id: cord-336488-opjjowcq
      author: Kenanidis, Eustathios
       title: Organizing an Orthopaedic Department During COVID-19 Pandemic to Mitigate In-Hospital Transmission: Experience From Greece
        date: 2020-06-17
       words: 3388
      flesch: 39
     summary: Pregnant, immunocompromised or over 60 years of age staff were protected; thus, we preferred to involve healthy younger personnel for the care of COVID-19 patients [12] . Two operating theatre complexes with negative pressure and ventilation systems and an integrated high-efficiency particulate air (HEPA) filter to decrease viral dissemination were chosen for surgery of COVID-19 patients [7, 9, 12, 15] .
    keywords: care; covid-19; hospital; orthopaedic; patients; sars; surgery; transmission
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        item: #6280 of 7819
          id: cord-336497-vzenzbw1
      author: Busch-Hallen, Jenny
       title: Impact of COVID-19 on maternal and child health
        date: 2020-08-03
       words: 553
      flesch: 31
     summary: The COVID-19 pandemic is already indirectly threatening breastfeeding practices (early initiation and exclusive and continued breastfeeding). Early estimates of the indirect effects of the COVID-19 pandemic on maternal and child mortality in low-income and middle-income countries: a modelling study Why invest, and what it will take to improve breastfeeding practices? International Code of Marketing of Breast-Milk Substitutes
    keywords: breastfeeding; covid-19
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        item: #6281 of 7819
          id: cord-336499-5flknpp4
      author: Ahmed, Aziza
       title: How the COVID-19 Response is Altering the Legal and Regulatory Landscape on Abortion
        date: 2020-04-29
       words: 2020
      flesch: 48
     summary: It is in this context that abortion access has been injected into the political and medical response to COVID-19. This essay describes the current status of the terrain and the potential long-term implications on abortion access and care.
    keywords: abortion; access; covid-19; elective; health
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        item: #6282 of 7819
          id: cord-336543-ydrmlujj
      author: Cavalli, Eugenio
       title: Entangling COVID-19 associated thrombosis into a secondary antiphospholipid antibody syndrome: Diagnostic and therapeutic perspectives (Review)
        date: 2020-06-25
       words: 5864
      flesch: 30
     summary: cOVId-19 pathophysiology: A review al; china Medical Treatment Expert group for covid-19: clinical characteristics of coronavirus disease 2019 in china The epidemiology and pathogenesis of coronavirus disease (cOVId-19) outbreak Physiological and pathological regulation of AcE2, the SARS-coV-2 receptor A pneumonia outbreak associated with a new coronavirus of probable bat origin differential expression of neuronal AcE2 in transgenic mice with overexpression of the brain renin-angiotensin system Boone cE and deconde AS: Association of chemosensory dysfunction and cOVId-19 in patients presenting with influenza-like symptoms Early transmission dynamics in Wuhan, china, of novel coronavirus-infected pneumonia Updated understanding of the outbreak of 2019 novel coronavirus (2019-ncoV) in Wuhan, china Features, evaluation and treatment coronavirus The extent of transmission of novel coronavirus in Wuhan, china, 2020 Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia cOVId-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis Analysis of coagulation parameters in patients with cOVId-19 in Shanghai, china Venous and arterial thromboembolic complications in cOVId-19 patients admitted to an academic hospital in Supported by the ESc Working group on Pulmonary circulation and Right Ventricular Function: cOVId-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up: JAcc State-of-the-Art Review Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy More on cOVId-19 coagulopathy in caucasian patients Thromboembolic events and apparent heparin resistance in patients infected with SARS-coV-2 The pathogenesis and treatment of the 'cytokine Storm' in cOVId-19 In the eye of the cOVId-19 cytokine storm complement associated microvascular injury and thrombosis in the pathogenesis of severe cOVId-19 infection: A report of five cases complement as a target in cOVId-19? Will complement inhibition be the new target in treating cOVId-19-related systemic thrombosis? The beneficial effects observed with hydroxychloroquine in APS patients (26, 43) has also been claimed in cOVId-19 patients but it needs, however, formal demonstration (43, 44) .
    keywords: abs; anti; aps; covid-19; infection; patients; sars; syndrome; thrombosis
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        item: #6283 of 7819
          id: cord-336549-xjrrw0wr
      author: Megahed, Naglaa A.
       title: Antivirus-built environment: lessons learned from covid-19 pandemic
        date: 2020-06-24
       words: 4805
      flesch: 44
     summary: Automation, voice technology, and facial recognition-based in artificial intelligence could influence post-pandemic architecture. BBC Is coronavirus pandemic accelerating the digitalization and automation of cities? 2019 novel coronavirus (COVID-19) pandemic: built environment considerations to reduce transmission Urbanization: Challenge and opportunity for soil functions and ecosystem services How COVID-19 will change the design of our cities Effect of green roofs on the efficiency of thermal performance of residential buildings in Egypt Postmodern urbanism Coronavirus is crowding limited outdoor spaces, Says FIU Architecture Professor Current Response and Management Decisions of the European Union to the COVID-19
    keywords: antivirus; architecture; cities; coronavirus; covid-19; design; environment; future; pandemic; planning
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        item: #6284 of 7819
          id: cord-336554-n8n5ii5k
      author: Singh, Thakur Uttam
       title: Drug repurposing approach to fight COVID-19
        date: 2020-09-05
       words: 13068
      flesch: 39
     summary: Further, darunavir has been used (600 mg tablet every 12 h) along with other anti-viral drugs and supportive therapy in the clinical management of COVID-19 patients presented with a range of MEWS from less than 3 to more than 4 in Italy [33] . Hydroxychloroquine phosphate (400 mg tablet every 12 h as a loading dose followed 200 mg tablet every 12 h for 10 days) or chloroquine phosphate (250 mg of two tablet every 12 h for 10 days) along with other anti-viral drugs and supportive therapy have been used in the clinical management of COVID-19 patients presented with a range of MEWS from less than 3 to more than 4 in Italy
    keywords: antiviral; arbidol; clinical; coronavirus; cov2; covid-19; disease; dose; drug; effects; hydroxychloroquine; infection; inhibitors; interferon; lopinavir; patients; protease; remdesivir; ribavirin; ritonavir; sars; study; therapy; tocilizumab; treatment; trial; use
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        item: #6285 of 7819
          id: cord-336563-hwemigk7
      author: Bhimraj, Adarsh
       title: Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19
        date: 2020-04-27
       words: 8317
      flesch: 36
     summary: A Randomized Control Trial (THDMS-COVID19) High-Dose Intravenous Immunoglobulin as a Therapeutic Option for Deteriorating Patients With Coronavirus Disease GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection Compassionate Use of Remdesivir for Patients with Severe COVID-19 SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Vascular and upper gastrointestinal effects of nonsteroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials Non-steroidal anti-inflammatory drug induced acute kidney injury in the community dwelling general population and people with chronic kidney disease: systematic review and meta-analysis Nonsteroidal antiinflammatory drugs may affect the presentation and course of community-acquired pneumonia Risks Related to the Use of Non-Steroidal Anti-Inflammatory Drugs in Community-Acquired Pneumonia in Adult and Pediatric Patients Efficacy of Addition of Naproxen in the Treatment of Critically Ill Patients Hospitalized for COVID-19 Infection (ENACOVID) HFSA/ACC/AHA statement addresses concerns re: using RAAS antagonists in COVID-19 Treating COVID-19-Off-Label Drug Use, Compassionate Use, and Randomized Clinical Trials During Pandemics Editorial Concern-Possible Reporting of the Same Patients With COVID-19 in Different Reports Steroid therapy and the risk of osteonecrosis in SARS patients: a dose-response meta-analysis The Ebola clinical trials: a precedent for research ethics in disasters Clinical research ethics for critically ill patients: a pandemic proposal Early observational research and registries during the 2009-2010 influenza A pandemic Choosing outcomes for clinical trials: a pragmatic perspective In an open label treatment trial, lopinavir-ritonavir with ribavirin reduced the mortality and requirement of intensive care support of hospitalized SARS patients compared with historical control
    keywords: clinical; covid-19; disease; evidence; guideline; outcomes; panel; patients; recommendations; risk; sars; studies; treatment; trials; use
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        item: #6286 of 7819
          id: cord-336585-19vwpjkt
      author: Adem, Şevki
       title: Caffeic acid derivatives (CAFDs) as inhibitors of SARS-CoV-2: CAFDs-based functional foods as a potential alternative approach to combat COVID-19
        date: 2020-08-22
       words: 3583
      flesch: 33
     summary: The crystal structures of the following SARS-CoV-2 proteins were retrieved from the protein data bank web site (http://www.rcsb.org/pdb): SARS-CoV-2 M pro (PDB ID: 6LU7: Resolution 2.16 Å) (Jin et al., 2020) , Nsp15 endoribonuclease (PDB ID: 6VWW) (Kim et al., 2020b) , coronavirus fusion protein (PDB ID: 6LXT) (Xia et al., 2020) , SARS-CoV-2 spike ectodomain (PDB ID: 6VYB) and spike glycoprotein (open state) (PDB ID: 6VXX) (Walls et al., 2020a) . SARS-CoV-2 genome possesses a complex organization encoding various structural as well as non-structural proteins (Nsps) (Kim et al., 2020a) .
    keywords: acid; cafds; cov-2; covid-19; interactions; potential; protein; sars; spike; virus
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        item: #6287 of 7819
          id: cord-336591-a31oe7kc
      author: Wong, Martin
       title: Evaluation on different non-pharmaceutical interventions during COVID-19 pandemic: an analysis of 139 countries
        date: 2020-06-21
       words: 739
      flesch: 39
     summary: The findings of this study showed that more stringent containment and control measures could potentially lead to better COVID-19 pandemic control. Modelling SARS-COV2 Spread in London: Approaches to Lift the Lockdown Variation in Government responses to COVID-19 The 2019 Novel Coronavirus COVID-19 (2019-nCoV) data repository by Johns Hopkins Centre for Systems Science and Engineering (CSSE).
    keywords: countries; covid-19; stringency
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        item: #6288 of 7819
          id: cord-336614-u6alc6rs
      author: Pérez-Belmonte, Luis M.
       title: Differences between Clinical Protocols for the Treatment of Coronavirus Disease 2019 (COVID-19) in Andalusia, Spain
        date: 2020-09-19
       words: 4741
      flesch: 31
     summary: The clinical presentation of the novel COVID-19 may vary from mild cases with fever, fatigue, and cough to moderate-severe cases involving pneumonia and multiorgan failure [10] , and several factors may predispose COVID-19 patients to adverse outcomes. The potential harm, such as delayed viral clearance, increased risk of secondary infection, and hyperglycemia episodes, have led to caution in their routine use in COVID-19 patients unless the patient had other conditions for which these are indicated
    keywords: covid-19; heparin; hospital; hydroxychloroquine; lopinavir; patients; pneumonia; protocols; treatment
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        item: #6289 of 7819
          id: cord-336669-i7yul1c1
      author: Walsh, Mary Norine
       title: COVID-19 pandemic and cardiovascular complications: what have we learned so far?
        date: 2020-06-15
       words: 1410
      flesch: 44
     summary: We received four general categories of case reports detailing an increased risk of arterial thrombosis during the COVID-19 pandemic. Case Reports The known into the unknown Brugada Syndrome and COVID-19.
    keywords: case; covid-19; jacc; reports
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        item: #6290 of 7819
          id: cord-336677-h62angfw
      author: Rousseau, Antoine
       title: Sars-Cov-2, Covid-19 Et Œil: Le Point Sur Les Données Publiées
        date: 2020-05-30
       words: 3191
      flesch: 40
     summary: [21, 22] , et est impliqué dans la réactivité des lymphocytes. En outre, ACE2 est impliquée dans la régulation du système rénine-angiotensine (que le virus pourrait par ce biais perturber, générant des troubles de la perméabilité tissulaire) et aussi dans la régulation du relargage par les lymphocytes de diverses cytokines, ce qui pourrait expliquer en partie les dysrégulations inflammatoires observées dans le COVID-19.
    keywords: coronavirus; cov-2; covid-19; dans; des; est; les; patients; pour; qui; sars; sur; une; virus
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        item: #6291 of 7819
          id: cord-336689-z3ayolzb
      author: Gaur, Uma
       title: Challenges and Opportunities of Preclinical Medical Education: COVID-19 Crisis and Beyond
        date: 2020-09-22
       words: 3646
      flesch: 34
     summary: The unprecedented use of online pedagogy as an emergency measure during COVID-19 period, with an adaptation to the new normal to deliver preclinical medical education, has brought both challenges and opportunities to medical education While COVID-19 has thrown many challenges for preclinical medical education, it has also created opportunities-academic leaders with servant leadership, distribution of leadership responsibilities, and clear lines of communication dealt with the situation aptly [1, [16]
    keywords: covid-19; education; learning; online; pandemic; schools; students; teaching
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        item: #6292 of 7819
          id: cord-336696-c3rbmysh
      author: Oberfeld, Blake
       title: SnapShot: COVID-19
        date: 2020-04-30
       words: 1231
      flesch: 34
     summary: The causative agent was characterized as a novel coronavirus, initially referred to as 2019-nCoV and renamed severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) (Zhou et al., 2020b) . Human coronaviruses include 229E, NL63, OC43, and HKU1, which are associated with mild seasonal illness, as well as viruses responsible for past outbreaks of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS).
    keywords: covid-19; disease; sars
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        item: #6293 of 7819
          id: cord-336702-2qa4u8gv
      author: Agarwal, Sangya
       title: Harnessing CAR T-cell Insights to Develop Treatments for Hyperinflammatory Responses in Patients with COVID-19
        date: 2020-04-17
       words: 2370
      flesch: 37
     summary: key: cord-336702-2qa4u8gv authors: Agarwal, Sangya; June, Carl H. title: Harnessing CAR T-cell Insights to Develop Treatments for Hyperinflammatory Responses in Patients with COVID-19 date: 2020-04-17 journal: Cancer Discov DOI: 10.1158/2159-8290.cd-20-0473 sha: doc_id: 336702 cord_uid: 2qa4u8gv Cytokine release and macrophage activation contribute to immunopathology after SARS-CoV-2 infection. We discuss approaches to decrease the morbidity and mortality in patients with COVID-19 by repurposing existing drugs previously developed for cancer therapy.
    keywords: cell; covid-19; crs; hlh; patients; sars; treatment
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        item: #6294 of 7819
          id: cord-336732-9zp5agja
      author: Williams, R. D.
       title: Seek COVER: Development and validation of a personalized risk calculator for COVID-19 outcomes in an international network
        date: 2020-05-27
       words: 4933
      flesch: 45
     summary: The models could aid in providing reassurance for low risk patients and shield high risk patients from COVID-19 during de-confinement to reduce the virus' impact on morbidity and mortality. The models could aid in providing reassurance for low risk patients and shield high risk patients from COVID-19 during de-confinement to reduce the virus' impact on morbidity and mortality. .
    keywords: cover; covid-19; license; medrxiv; model; patients; preprint; risk
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        item: #6295 of 7819
          id: cord-336735-pk7sx81r
      author: Veerapandiyan, Aravindhan
       title: Spinal muscular atrophy care in the COVID‐19 pandemic era
        date: 2020-05-03
       words: 1423
      flesch: 38
     summary: In this study, we discuss consensus recommendations pertaining to care of SMA patients during the pandemic. In some instances, this has interfered with planned treatments for SMA patients.
    keywords: atrophy; covid-19; patients; sma; spinal
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        item: #6296 of 7819
          id: cord-336746-a0thtd1m
      author: Uwins, C.
       title: COVID‐19 pandemic impact on gynaecological cancers: a perspective
        date: 2020-06-03
       words: 566
      flesch: 44
     summary: This is key at a time when we are trying to reduce hospital exposure for our patients, both to protect them and to maintain capacity for the care of COVID-19 patients. Cancer surgery is urgent and needs to be considered as such or we will see further needless deaths due to cancer added to the COVID-19 death toll.
    keywords: covid-19; patients
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        item: #6297 of 7819
          id: cord-336753-4212ftlc
      author: Luo, Lu
       title: Analysis on herbal medicines utilized for treatment of COVID-19
        date: 2020-05-27
       words: 3560
      flesch: 23
     summary: key: cord-336753-4212ftlc authors: Luo, Lu; Jiang, Jingwen; Wang, Cheng; Fitzgerald, Martin; Hu, Weifeng; Zhou, Yumei; Zhang, Hui; Chen, Shilin title: Analysis on herbal medicines utilized for treatment of COVID-19 date: 2020-05-27 journal: Acta Pharm Sin B DOI: 10.1016/j.apsb.2020.05.007 sha: doc_id: 336753 cord_uid: 4212ftlc As coronavirus disease 2019 (COVID-19) pandemic poses a substantial global public health threat, traditional Chinese medicine (TCM) was used in 91.50% of the COVID-19 cases in China, showing encouraging results in improving symptom management and reducing the deterioration, mortality, and recurrence rates. Shanghai Scientific & Technical Publishers Lab of system pharmacology Research on component law of Chinese patent medicine for anti-influenza and development of new recipes for anti-influenza by unsupervised data mining methods A hierarchical clustering based on mutual information maximization Molecular scaffold analysis of natural products databases in the public domain Classification of mixtures of Chinese herbal medicines based on a self-organizing map (SOM)
    keywords: analysis; anti; china; chinese; covid-19; disease; effects; formulae; medicine; tcm; treatment
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        item: #6298 of 7819
          id: cord-336769-5x6xjuew
      author: Payne, Daniel C.
       title: SARS-CoV-2 Infections and Serologic Responses from a Sample of U.S. Navy Service Members — USS Theodore Roosevelt, April 2020
        date: 2020-06-12
       words: 2567
      flesch: 35
     summary: Reported symptoms were categorized using the Council of State and Territorial Epidemiologists (CSTE) case definition for COVID-19 (5), including category A (at least cough or shortness of breath/difficulty breathing) and category B (no cough or shortness of breath, but two or more other symptoms*) or neither. Public health responses to COVID-19 outbreaks on cruise ships-worldwide
    keywords: cov-2; covid-19; infection; participants; sars
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        item: #6299 of 7819
          id: cord-336771-5hh1l1dt
      author: Lemos, George Azevedo
       title: Human anatomy education and management of anatomic specimens during and after COVID-19 pandemic: Ethical, legal and biosafety aspects
        date: 2020-10-03
       words: 2766
      flesch: 33
     summary: The In this paper we do not aim to discuss the best teaching methods in anatomy, but to discuss the ethical and legal aspects related to the exposure of images and videos of human anatomic specimens during online classes. Besides, we instigate the debate on the legal and ethical aspects of the exhibition of images of human anatomic specimens and their parts, guided by the Brazilian legislation.
    keywords: anatomy; bodies; body; covid-19; education; family; specimens
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        item: #6300 of 7819
          id: cord-336782-0zkb39v1
      author: Fraile Gutiérrez, V.
       title: Narrative review of ultrasound in the management of the critically ill patient with SARS-CoV-2 infection (COVID-19): clinical applications in intensive care medicine
        date: 2020-11-02
       words: 6663
      flesch: 39
     summary: Recomendations of the Cardiological Intensive Care and CPR Working Group of the Spanish Society of Intensive Care and Coronary Units Point-of-care lung ultrasound in patients with COVID-19 -a narrative review Chinese Critical Care Ultrasound Study G. Findings of lung ultrasonography of novel corona virus pneumonia during the 2019-2020 epidemic COVID-19 outbreak: less stethoscope, more ultrasound Lung ultrasound and B-lines quantification inaccuracy: B sure to have the right solution Point-of-Care Lung Ultrasound findings in novel coronavirus disease-19 pnemoniae: a case report and potential applications during COVID-19 outbreak Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents COVID-19 Lo que el técnico tiene que saber Products with emerging viral pathogens and human coronavirus claims for use against SARS-CoV-2 Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19) Verification of Endotracheal Tube Placement The assessment of four different methods to verify tracheal tube placement in the critical care setting Comparison of three different methods to confirm tracheal tube placement in emergency intubation ) for confirming endotracheal tube placement during emergency intubation Confirmation of endotracheal tube placement after intubation using the ultrasound sliding lung sign BLUE-protocol and FALLS-protocol: two applications of lung ultrasound in the critically ill A bedside ultrasound sign ruling out pneumothorax in the critically ill. Lung sliding Thoracic ultrasonography: a narrative review Chest ultrasound in acute respiratory distress syndrome Global and regional diagnostic accuracy of lung ultrasound compared to CT in patients with acute respiratory distress syndrome Relevance of lung ultrasound in the diagnosis of acute respiratory failure: the BLUE protocol Six versus eight and twenty-eight scan sites for B-line assessment: differences in examination time and findings Bedside ultrasound assessment of positive end-expiratory pressure-induced lung recruitment Ultrasound assessment of lung aeration loss during a successful weaning trial predicts postextubation distress* Diagnosis of pneumothorax by radiography and ultrasonography: a meta-analysis Pleural ultrasonography versus chest radiography for the diagnosis of pneumothorax: review of the literature and meta-analysis Thelung point: an ultrasound sign specific to pneumothorax Sonographic diagnosis of pneumothorax Focused abdominal sonogram for trauma: the learning curve of nonradiologist clinicians in detecting hemoperitoneum Pleural ultrasonography Whole Body Ultrasonography in the Critically Ill Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Tissue Plasminogen Activator (tPA) treatment for COVID-19 Associated Acute Respiratory Distress Syndrome (ARDS): a case series Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Real-time ultrasound-guided catheterisation of the internal jugular vein: a prospective comparison with the landmark technique in critical care patients Guidelines for performing ultrasound guided vascular cannulation: recommendations of the American Society of Echocardiography and the Society of Cardiovascular Anesthesiologists Guidelines on the use of ultrasound guidance for vascular access Anatomical variations in the internal jugular veins of cancer patients affecting central venous access.
    keywords: acute; cardiac; care; cov-2; covid-19; echocardiography; fig; lung; lung ultrasound; patients; pattern; sars; ultrasound; ventricular
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        item: #6301 of 7819
          id: cord-336790-29im4gxw
      author: Violetis, Odyssefs A.
       title: COVID-19 Infection and Haematological Involvement: a Review of Epidemiology, Pathophysiology and Prognosis of Full Blood Count Findings
        date: 2020-06-29
       words: 2667
      flesch: 38
     summary: A novel coronavirus from patients with pneumonia in China Identification of a novel coronavirus in patients with severe acute respiratory syndrome Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome Cardiovascular disease and COVID-19 Neurologic manifestations of hospitalized patients with coronavirus disease COVID-19 and its implications for thrombosis and anticoagulation COVID-19 and thrombotic or thromboembolic disease : implications for prevention, antithrombotic therapy and follow-up Covid-19 and the digestive system COVID-19: consider cytokine storm and immunosuppression Clinical characteristics of coronavirus disease 2019 in China Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical features of patients infected with 2019 novel coronavirus in Wuhan Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis Complex immune dysregulation in COVID-19 patients with severe respiratory failure Dysregulation of immune response in patients with COVID-19 in Wuhan, China The critical role of laboratory medicine during coronavirus disease 2019 (COVID-19) and other viral outbreaks Eosinophil count in severe coronavirus disease 2019 Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa Hematological findings and complications of COVID-19 Hematologic parameters in patients with COVID-19 infection Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington state Suppressed T cell-mediated immunity in patients with COVID-19: a clinical retrospective study in Wuhan Characteristics of peripheral lymphocyte subset alteration in COVID-19 pneumonia Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: a meta-analysis Mechanism of thrombocytopenia in COVID-19 patients Platelet biogenesis in the lung circulation Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia A meta-analysis conducted by Lippi G. et al. included 9 studies with a total of 1779 COVID-19 patients examining the association between thrombocytopenia and severity of the disease.
    keywords: coronavirus; count; covid-19; disease; infection; patients
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        item: #6302 of 7819
          id: cord-336794-ok6j19kf
      author: Lu, Meiqi
       title: Efficacy and safety of Chinese patent medicine injection for COVID-19: A protocol for systematic review and meta-analysis
        date: 2020-06-19
       words: 2514
      flesch: 42
     summary: The purpose of this study was to evaluate the efficacy and safety of Chinese patent medicine injection in the treatment of COVID-19 and to explore the role of Chinese medicine in the treatment of COVID-19. key: cord-336794-ok6j19kf authors: Lu, Meiqi; Lu, Zhen; Zhang, Ting; Wang, Wei; Xue, Ye; Cao, Zhiqun title: Efficacy and safety of Chinese patent medicine injection for COVID-19:
    keywords: analysis; bias; chinese; covid-19; injection; medicine; treatment
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        item: #6303 of 7819
          id: cord-336810-77wq9laa
      author: Klocperk, Adam
       title: Complex Immunometabolic Profiling Reveals the Activation of Cellular Immunity and Biliary Lesions in Patients with Severe COVID-19
        date: 2020-09-17
       words: 4688
      flesch: 36
     summary: Individually, laboratory abnormalities have been reported in COVID-19 patients, including an elevation of inflammatory markers and liver enzymes, abnormal renal function tests, and an elevated serum soluble interleukin 2 (IL-2) receptor (sIL2R) and IL-6. As a contribution to the current knowledge pool, our report describes a representative cohort of COVID-19 patients hospitalized during the pandemic in a large Czech hospital.
    keywords: cells; course; covid-19; disease; elevation; figure; liver; markers; patients; sars; study
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        item: #6304 of 7819
          id: cord-336822-cw37jrt2
      author: Dennison Himmelfarb, Cheryl R.
       title: Coronavirus Disease (COVID-19): Implications for Cardiovascular and Socially At-risk Populations
        date: 2020-05-06
       words: 2263
      flesch: 38
     summary: • Avoid crowds and travel, and limit contact with others Additional considerations specific to those with an underlying cardiovascular disease: • Stay up-to-date with vaccinations such as flu and pneumonia Manage stress by taking a few minutes each day to meditate, contact family and friends to stay socially connected, and improve sleep hygiene Consider electronic consulting (telehealth) phone, videoconferencing, or messaging options for visits Continue taking angiotensin-converting enzyme inhibitors or angiotensin receptor blocker medications as prescribed for heart failure, hypertension, or ischemic heart disease • Contact health provider immediately if experiencing fever or sore throat, and call 911 if experiencing shortness of breath or warning signs of a heart attack or stroke • In the presence of COVID-19 infection, consider need for intensified antiplatelet therapy in those with a history of previous coronary intervention Coronavirus (COVID-19) resources Report of the WHO-China joint mission on coronavirus disease (COVID-19) Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and metaanalysis Correlates of health literacy and its impact on illness beliefs for emergency department patients with acute heart failure Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China Coronaviruses and the cardiovascular system: acute and long-term implications SARS-CoV2: should inhibitors of the renin-angiotensin system be withdrawn in patients with COVID-19? The CDC released general preventive measures for COVID-19 infection; however, socially at-risk persons and those with underlying cardiovascular and chronic conditions bear the burden of an elevated risk for developing severe complications and death.
    keywords: cardiovascular; covid-19; disease; health; healthcare; heart; risk
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        item: #6305 of 7819
          id: cord-336845-7ofgekoj
      author: Donthu, Naveen
       title: Effects of COVID-19 on Business and Research
        date: 2020-06-09
       words: 5229
      flesch: 50
     summary: There has been a long history of fear of pandemic outbreaks. We should also make an effort to learn from the consequences of pandemic outbreaks to prepare our societies for if-and, more likely, when-this happens again.
    keywords: businesses; consumer; countries; covid-19; firms; future; need; outbreak; pandemic; people; society
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        item: #6306 of 7819
          id: cord-336865-ss4a6coi
      author: Brunner, Maximilian
       title: Oncological colorectal surgery during the COVID-19pandemic—a national survey
        date: 2020-07-29
       words: 2170
      flesch: 41
     summary: The aim of this study was to clarify the surgical supply situation of oncological colorectal patients in Germany during limitations of the OR caseload due to the COVID-19 pandemic. Eighty-seven percent of the participating hospitals had to reduce their total surgical caseload and 34% their surgical volume for oncological colorectal patients during COVID-19 pandemic.
    keywords: colorectal; covid-19; hospitals; pandemic; patients
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        item: #6307 of 7819
          id: cord-336870-nirg3269
      author: Abebe, Endeshaw Chekol
       title: The newly emerged COVID-19 disease: a systemic review
        date: 2020-07-08
       words: 4167
      flesch: 52
     summary: The global distribution of COVID-19 cases as of March 12, 2020 WHO situation reports 52 is shown in Fig. The total number of COVID-19 cases is likely to be higher due to the inherent difficulties in identifying and counting mild and asymptomatic cases, especially in those developing countries having poor settings for case detection.
    keywords: cases; china; coronavirus; covid-19; novel; patients; sars; symptoms
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        item: #6308 of 7819
          id: cord-336922-ent5oimq
      author: Solís, Patricio
       title: COVID-19 Fatality and Comorbidity Risk Factors among Confirmed Patients in Mexico
        date: 2020-04-25
       words: 2525
      flesch: 47
     summary: In this paper we estimate fatality risks based on survival analysis methods, calculated from individual-level data on symptomatic patients confirmed with COVID-19 recently released by the Mexican Ministry of Health. Fatality risks sharply rise with age, and significantly increase for males (59%) and individuals with comorbidities (38%-168%, depending on the disease).
    keywords: covid-19; fatality; patients; risk
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        item: #6309 of 7819
          id: cord-336924-7xcbtn3q
      author: Borghi, Maria Orietta
       title: Anti-Phospholipid Antibodies in COVID-19 Are Different From Those Detectable in the Anti-Phospholipid Syndrome
        date: 2020-10-15
       words: 3194
      flesch: 41
     summary: This data is in line with the unusual epitope specificity of anti-b 2 GPI antibodies documented in Figure 2 , supporting the hypothesis that aPL found in COVID-19 patients are different from aPL found in APS patients. Hence, while transitory aPL are likely to be clinically irrelevant in COVID-19 patients as in other infections (33) , detection of aPL may be useful for identifying patients potentially at risk of thrombosis after the hospital discharge.
    keywords: anti; antibodies; apl; aps; covid-19; gpi; patients
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        item: #6310 of 7819
          id: cord-336940-6rgmpy5r
      author: Russell, B. S.
       title: Initial Challenges of Caregiving During COVID-19: Caregiver Burden, Mental Health, and the Parent–Child Relationship
        date: 2020-08-04
       words: 7079
      flesch: 37
     summary: The multi-group model indicated no significant association between the control (focal child age) and any endogenous variables (parent perceived child stress, child parent relationship conflict and child parent relationship closeness). Contrary to our hypothesis, generalized anxiety symptoms did not significantly predict child parent relationship conflict (β = − 0.22 and − 0.23, p < 0.01) or child parent relationship closeness (β = 0.21 and 0.26, p = ns) for male or female caregivers, respectively.
    keywords: anxiety; burden; caregivers; child; children; conflict; covid-19; depression; health; parent; relationship; stress
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        item: #6311 of 7819
          id: cord-336942-2mvcyvbl
      author: Liu, Cindy H.
       title: Factors Associated with Depression, Anxiety, and PTSD Symptomatology During the COVID-19 Pandemic: Clinical Implications for U.S. Young Adult Mental Health
        date: 2020-06-01
       words: 4765
      flesch: 38
     summary: Compared to Whites, Asian Americans were less likely to report high levels across mental health symptoms, and Hispanic/Latinos were less likely to report high levels of anxiety. COVID-19-related worry (e.g., maintaining employment, getting tested for coronavirus) may be linked to mental health symptoms.
    keywords: anxiety; covid-19; depression; health; levels; pandemic; ptsd; support; symptoms
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        item: #6312 of 7819
          id: cord-336954-rh88lod0
      author: Shim, Eunha
       title: Transmission potential and severity of COVID-19 in South Korea
        date: 2020-03-18
       words: 2977
      flesch: 43
     summary: Euro surveillance : bulletin Europeen sur les maladies transmissibles Novel coronavirus 2019-nCoV: early estimation of epidemiological parameters and epidemic predictions Real-time forecasts of the COVID-19 epidemic in China from Surge in South Korea virus cases linked to church 'super-spreader'. Next, to estimate the most recent estimate of Rt, we simulate the progression of incident cases from GGM, and apply the discretized probability distribution ( ) of the generation interval using the renewal equation (H. Nishiura, 2009 , Nishiura and Chowell, 2014 , Paine et al., 2010 given by In the renewal equation we denote the local incidence at calendar time by , and the raw incidence J o u r n a l P r e -p r o o f of imported cases at calendar time by .
    keywords: cases; covid-19; growth; korea; number; transmission
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        item: #6313 of 7819
          id: cord-337020-7dhx8f4x
      author: El Haj, Mohamad
       title: High depression and anxiety in people with Alzheimer's disease living in retirement homes during the Covid-19 crisis
        date: 2020-07-13
       words: 3178
      flesch: 39
     summary: Research suggests that 25 % to 71 % people with AD experience anxiety during the course of the Covid-19 and depression in AD 7 disease (Mintzer, Brawman-Mintzer, Mirski, & Barkin, 2005) . Also, 25 % to 71 % people with AD experience anxiety during the course of the disease (Mintzer et al., 2005) .
    keywords: anxiety; covid-19; crisis; depression; participants; retirement
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        item: #6314 of 7819
          id: cord-337026-osgi06o4
      author: Panoutsopoulos, Alexios A.
       title: Conjunctivitis as a Sentinel of SARS-CoV-2 Infection: a Need of Revision for Mild Symptoms
        date: 2020-06-19
       words: 3183
      flesch: 38
     summary: The Molecular Biology of Coronaviruses and SARS-CoV-2 Coronaviruses (CoVs) are RNA viruses with the largest RNA in base length identified so far and belong to the Coronaviridae family. Except for DNA viruses though, RNA viruses are often associated with conjunctivitis.
    keywords: cell; conjunctivitis; coronavirus; cov-2; covid-19; host; protein; receptor; sars; virus
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        item: #6315 of 7819
          id: cord-337060-jkzbyqtm
      author: Alqurshi, Abdulmalik
       title: Investigating the impact of COVID-19 lockdown on pharmaceutical education in Saudi Arabia – A call for a remote teaching contingency strategy
        date: 2020-08-03
       words: 6571
      flesch: 39
     summary: To avoid participations from academics in all areas, the questionnaire was adapted with an opening filtering question considering only faculty members that have participated in teaching and assessing pharmacy students, in Saudi Arabian institutions, during the lockdown. The teacher-targeted questionnaire was directed to pharmacy program managerial teams for distribution amongst faculty members, whilst the student-targeted questionnaire was directed to student group leaders to distribute amongst pharmacy students from all program years.
    keywords: alternative; assessment; education; fig; learning; lockdown; methods; pharmacy; saudi; student; teachers; teaching
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        item: #6316 of 7819
          id: cord-337061-nefb7a8c
      author: Roberts, Stephanie A.
       title: Considerations for Providing Pediatric Gender-Affirmative Care During the COVID-19 Pandemic
        date: 2020-09-14
       words: 1461
      flesch: 28
     summary: Unfortunately, many gender diverse youth have experienced delays in medically necessary treatment (e.g., pubertal suppression, hormone therapy, surgeries, etc.) and potentially have received the unintended, yet damaging message, that GAC is not a priority; therefore, it is important that multidisciplinary professionals working with gender diverse youth and their families counter this narrative. key: cord-337061-nefb7a8c authors: Roberts, Stephanie A.; Williams, Coleen R.; Grimstad, Frances W. title: Considerations for Providing Pediatric Gender-Affirmative Care During the COVID-19 Pandemic date: 2020-09-14 journal: J Adolesc Health DOI: 10.1016/j.jadohealth.2020.08.018 sha: doc_id: 337061 cord_uid: nefb7a8c nan As interdisciplinary professionals working with gender diverse youth, it is crucial that we continue to provide access to gender-affirming care (GAC) during the COVID-19 pandemic.
    keywords: gender; health; pandemic; transgender; youth
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        item: #6317 of 7819
          id: cord-337082-2xas41mj
      author: Akoumianakis, Ioannis
       title: The renin–angiotensin–aldosterone system as a link between obesity and coronavirus disease 2019 severity
        date: 2020-06-22
       words: 3529
      flesch: 28
     summary: Obesity affects a great number of people worldwide, and importantly, it has been associated with increased COVID-19 severity. 17 Optimal interventions in COVID-19 patients with obesity are controversial because of lack of underlying mechanism characterization.
    keywords: ace2; aldosterone; angii; angiotensin; covid-19; obesity; raas; renin; system
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        item: #6318 of 7819
          id: cord-337089-ksh62ni0
      author: Salajegheh Tazerji, Sina
       title: Transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to animals: an updated review
        date: 2020-09-21
       words: 4909
      flesch: 46
     summary: 31 Department of Animal Wealth Development, Faculty of Veterinary Medicine Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding A novel coronavirus outbreak of global health concern Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): the epidemic and the challenges A novel coronavirus emerging in China-key questions for impact assessment Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2 Discovery of a novel coronavirus, China Rattus coronavirus HKU24, from Norway rats supports the murine origin of Betacoronavirus 1 and has implications for the ancestor of Betacoronavirus lineage A The COVID-19 pandemic: a comprehensive review of taxonomy, genetics, epidemiology, diagnosis, treatment, and control Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus Emerging coronaviruses: genome structure, replication, and pathogenesis Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2 Epidemiology, genetic recombination, and pathogenesis of coronaviruses Coronavirus infection in equines: a review Efficient assembly and release of SARS coronavirus-like particles by a heterologous expression system MERS-CoV virus-like particles produced in insect cells induce specific humoural and cellular immunity in rhesus macaques Emerging novel coronavirus (2019-nCoV)-current scenario, evolutionary perspective based on genome analysis and recent developments Evolutionary trajectory for the emergence of novel coronavirus SARS-CoV-2 The Phyre2 web portal for protein modeling, prediction and analysis The proximal origin of SARS-CoV-2 Low-level of infection whit COVID-19 in pet dog Molecular basis of COVID-19 relationships in different species: a one health perspective Novel SARS-CoV-2/COVID-19: origin, pathogenesis, genes and genetic variations, immune responses and phylogenetic analysis World Health Organization WHO: summary table of SARS cases by country Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats Bats are natural reservoirs of SARS-like coronaviruses SARS virus infection of cats and ferrets Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans Middle East Although possible protection caused by the possession of a pet has not yet been found, the frequent occurrence of coronavirus in canines could help the human immune system develop a better response against SARS-CoV-2 [41] .
    keywords: animals; cats; coronavirus; cov-2; covid-19; humans; novel; protein; sars; spike; studies; transmission
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        item: #6319 of 7819
          id: cord-337098-33yj5g5v
      author: Agarwal, Shivani
       title: Preadmission Diabetes-Specific Risk Factors for Mortality in Hospitalized Patients With Diabetes and Coronavirus Disease 2019
        date: 2020-08-07
       words: 3631
      flesch: 34
     summary: However, few studies have looked at the effect of BMI as a risk factor of COVID-19 mortality independent of diabetes. Chronic kidney disease may lead to electrolyte and fluid shifts that increase risk for COVID-19 cardiovascular mortality (27) .
    keywords: covid-19; diabetes; disease; hba; mortality; patients
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        item: #6320 of 7819
          id: cord-337142-3n9edoy8
      author: Djakpo, Dodji Kossi
       title: Blood routine test in mild and common 2019 coronavirus (COVID-19) patients
        date: 2020-08-07
       words: 1967
      flesch: 53
     summary: Patients with negative results for COVID-19 and patients presenting with severe and critical conditions were excluded from the present study. As more is being discovered about this virus, we aim to report findings of the complete blood count (CBC) of COVID-19 patients.
    keywords: coronavirus; covid-19; crp; patients; study
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        item: #6321 of 7819
          id: cord-337163-i8ysgucd
      author: Desai, Rupak
       title: COVID-19 and Shock: A Cautionary Tale for Elderly Patients from a Pooled Analysis
        date: 2020-04-10
       words: 631
      flesch: 42
     summary: Although the awareness of the natural progression of COVID-19 is increasing with cardiovascular risk factors and older age being frequently identified as major risk factors for poor survival in COVID-19 patients, our knowledge remains limited on the pooled prevalence of shock and its impact on predicting mortality in COVID-19 infection. While the predominant complication of COVID-19 is an acute respiratory illness which could lead to acute respiratory distress syndrome, COVID-19 patients with cardiovascular complications and sepsis have a heightened risk of developing shock with potential in-hospital mortality during the disease course.
    keywords: covid-19; shock
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        item: #6322 of 7819
          id: cord-337169-wv9n2e2o
      author: Le Roux, Gael
       title: COVID-19: home poisoning throughout the containment period
        date: 2020-04-25
       words: 360
      flesch: 43
     summary: Although health systems have to deal with such disasters to decrease massive contaminations, several countries, such as France, have implemented containment measures. Worldwide, prevention of such home poisonings is urgently needed to avoid unnecessary emergency medical system use in such critical times.
    keywords: containment; measures
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        item: #6323 of 7819
          id: cord-337186-5zwt2bfo
      author: Fero, Katherine E.
       title: Perceived Impact of Urologic Surgery Training Program Modifications due to COVID-19 in the United States
        date: 2020-06-06
       words: 3116
      flesch: 34
     summary: In this study, we aim to assess urology residency program modifications in the context of COVID-19, and perceptions of the impact on urology trainees. In this study, we aim to assess urology residency program modifications in the context of COVID-19, and perceptions of the impact on urology trainees.
    keywords: covid-19; program; regions; residents; respondents; urology; volume
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        item: #6324 of 7819
          id: cord-337204-14gxpeaf
      author: Piciucchi, Matteo
       title: Preliminary considerations regarding the risk of COVID-19 and disease severity in chronic gastrointestinal conditions
        date: 2020-05-25
       words: 1641
      flesch: 38
     summary: Similarly, chronic pneumopathy, chronic kidney diseases, immunosuppression, and oncological conditions were found to be highly prevalent in COVID-19 patients, especially in those who progress to SARS and require intensive care A retrospective analysis of data from 1590 hospitalized COVID-19 patients in epicentral and nonepicentral areas of China did not show a high prevalence of preexistent chronic GI comorbidities in these patients [7] .
    keywords: covid-19; disease; infection; patients
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        item: #6325 of 7819
          id: cord-337220-yv7qdvzi
      author: Demeke, Addis
       title: Biosensor and molecular-based methods for the detection of human coronaviruses: A review
        date: 2020-09-08
       words: 2220
      flesch: 5
     summary: The rise of graphene Label-free graphene biosensor targeting cancer molecules based on non-covalent 733 modification Field-736 effect transistor biosensor for rapid detection of Ebola antigen Localized surface plasmon coupled fluorescence fiber-optic biosensor with gold nanoparticles Sensitive Detection of Dengue Virus Type 2 E-Proteins Signals 744 Using Self-Assembled Monolayers/Reduced Graphene Oxide-PAMAM Dendrimer Thin Film-745 SPR Optical Sensor An alternative medical diagnosis method: 748 Biosensors for virus detection A multi-virus detectable microfluidic 751 electrochemical immunosensor for simultaneous detection of H1N1, H5N1, and H7N9 virus 752 using ZnO nanorods for sensitivity enhancement Label-free detection of influenza viruses using a reduced 755 graphene oxide-based electrochemical immunosensor integrated with a microfluidic platform A highly sensitive electrochemical immunosensor for 759 hepatitis B virus surface antigen detection based on Hemin/G-quadruplex horseradish 760 peroxidase-mimicking DNAzyme-signal amplification A sensitive electrochemical immunosensor for label-free detection of Zika-virus protein Development of a portable 767 and disposable NS1 based electrochemical immunosensor for early diagnosis of dengue virus, 768 Anal Chim An electrochemical immunosensor for the corona virus associated 771 with the Middle East respiratory syndrome using an array of gold nanoparticle-modified carbon 772 electrodes Paper-based microfluidic point-of-care diagnostic 775 devices Recent developments in paper-778 based microfluidic devices Electrochemistry on paper-based analytical devices: a review Sensing approaches on paper-based devices: a review Recent advances in paper-based sensors The challenge of emerging and re-emerging 791 infectious diseases Emerging infectious diseases: threats to human health and 794 global stability Emerging viral diseases Bushmeat and emerging 800 infectious diseases: lessons from Africa, Problematic Wildlife Introduction to Foodborne Pathogens One Health, emerging infectious diseases 807 and wildlife: two decades of progress? Infectious disease management through point-of-care 810 personalized medicine molecular diagnostic technologies Development of rapid, automated diagnostics for infectious disease: 814 advances and challenges Rapid infectious diseases diagnostics using Smartphones Emerging infectious diseases: public 820 health issues for the 21st century Methods for reducing biosensor membrane biofouling Kinetic screening of antibodies from crude 826 hybridoma samples using Biacore 452 Evaluation of Nucleocapsid and Spike Protein-based ELISAs for detecting antibodies against 453 SARS-CoV-2 Stability issues of RT-PCR 456 testing of SARS-CoV-2 for hospitalized patients clinically diagnosed with COVID-19 Real-time RT-PCR in COVID-19 detection: issues affecting 460 the results Early diagnosis of SARS coronavirus infection by real time RT-PCR Multiple-centre clinical evaluation of an ultrafast single-tube 469 assay for SARS-CoV-2 RNA Rapid and visual detection of 2019 novel coronavirus (SARS-CoV-2) by a reverse transcription 473 loop-mediated isothermal amplification assay Rapid and sensitive detection of COVID-19 using CRISPR/Cas12a-based detection with naked 477 eye readout, CRISPR/Cas12a-NER CRISPR-Cas12-based detection of 482 SARS-CoV-2 Antibody responses to SARS-490 CoV-2 in patients with COVID-19 A serological assay to detect SARS-CoV-2 497 seroconversion in humans 500 Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-501 reactivity with SARS-CoV Potent neutralizing antibodies in the sera of convalescent 505 COVID-19 patients are directed against conserved linear epitopes on the SARS-CoV-2 spike 506 protein 509 Treatment of 5 critically ill patients with COVID-19 with convalescent plasma Detection of SARS-CoV-2-Specific Humoral and Cellular Immunity in COVID-19 Convalescent Individuals Potential rapid diagnostics, vaccine and therapeutics for 519 2019 novel coronavirus (2019-nCoV): a systematic review Performance of radiologists in differentiating COVID-19 from viral pneumonia on 523 chest CT CT features of coronavirus disease 2019 (COVID-19) 526 pneumonia in 62 patients in Wuhan, China Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-575 CoV-2 infection diagnosis Correlation of 578 chest CT and RT-PCR testing in coronavirus disease 2019 (COVID-19) in China: a report of 579 1014 cases Biosensors and bio-based methods for the separation and detection of 582 foodborne pathogens One day to one hour: how quickly can foodborne pathogens be detected?
    keywords: biosensor; cov-2; covid-19; detection; disease; sars; virus
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        item: #6326 of 7819
          id: cord-337248-thzox29o
      author: Tsolaki, Vasiliki
       title: Right ventricular dilation: The additive effect of mechanical ventilation on pulmonary embolism in Covid-19 patients
        date: 2020-08-04
       words: 979
      flesch: 29
     summary: [6]; Yet, heart-lung interactions may be pronounced in Covid-19 patients under mechanical ventilation. In conclusion, Covid-19 patients present a state of hypercoagulability and are at increased risk to suffer from the formation of pulmonary vascular macrothrombi; van Dam's study confirms this notion.
    keywords: covid-19; lung; patients
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        item: #6327 of 7819
          id: cord-337256-b3j3kg73
      author: Wang, Peipei
       title: Prediction of Epidemic Trends in COVID-19 with Logistic Model and Machine Learning Technics
        date: 2020-07-01
       words: 1945
      flesch: 51
     summary: We first apply Logistic model to fit the curve and calculate the 200 time with fastest growing rate, then use Prophet to make a prediction. Logistic is often used in regression fitting of time series data due to its simple principle and efficient calculation.
    keywords: cases; covid-19; epidemic; growth; number
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        item: #6328 of 7819
          id: cord-337269-bh3qbn3q
      author: Bajracharya, Aliza
       title: Scoping the perplexing effect of the COVID pandemic in Nepal, and the appraisal for precautionary measures from its lurking aftermath
        date: 2020-06-11
       words: 987
      flesch: 54
     summary: This pandemic has also eclipsed other health issues that shouldn't be neglected. This can magnify efficiencies, effectiveness, and enhance the quality of health services.
    keywords: covid; health; pandemic
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        item: #6329 of 7819
          id: cord-337275-phgfpzbt
      author: Andrew, Jones
       title: Is Spread of COVID-19 a Chaotic Epidemic?
        date: 2020-10-20
       words: 3657
      flesch: 46
     summary: Our mathematical examination of COVID-19 epidemic data in different countries reveals similarity of this dynamic to the chaotic behavior of many dynamics systems, such as logistic maps. In order to examine this hypothesis we have analysed COVID-19 epidemic data from different countries.
    keywords: behavior; countries; covid-19; data; epidemic; spread; system
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        item: #6330 of 7819
          id: cord-337297-fkw8780t
      author: Fan, Siyuan
       title: Neurological Manifestations in Critically Ill Patients With COVID-19: A Retrospective Study
        date: 2020-07-10
       words: 4703
      flesch: 36
     summary: Similarly, in a previous report of COVID-19 patients with ischemic stroke, all six stroke patients had large-vessel occlusion and three of them had multiterritory infarcts (21) . Furthermore, compared with patients without a cerebrovascular event, a significantly higher prevalence of antiphospholipid antibodies was observed in stroke patients.
    keywords: case; complications; coronavirus; covid-19; disease; ischemic; patients; sars; stroke; study
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        item: #6331 of 7819
          id: cord-337302-fpz2jfuj
      author: Abdihamid, Omar
       title: The Landscape of COVID-19 in Cancer Patients: Prevalence, Impacts, and Recommendations
        date: 2020-09-23
       words: 5970
      flesch: 43
     summary: The infection rate of SARS-CoV-2 in cancer patients in China was 0.79% (12 of 1524 patients; 95% CI, 0.31.2%). The case fatality rate of COVID-19 in the overall population ranges from 2.3 to 8.0%; among these, the case fatality rate for cancer patients is at 5.6%.
    keywords: cancer; care; china; coronavirus; cov-2; covid-19; disease; pandemic; patients; risk; sars; study; treatment
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        item: #6332 of 7819
          id: cord-337359-kvb7moqt
      author: Wells, Mike
       title: Ideas and the origin of evidence during the COVID-19 pandemic
        date: 2020-06-17
       words: 1248
      flesch: 57
     summary: Ideas that are of uncertain value may spawn further ideas of unquestionable value. They generate new ideas.
    keywords: covid-19; ideas; need
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        item: #6333 of 7819
          id: cord-337430-c2vdnml7
      author: Timpka, Toomas
       title: Sports Health During the SARS-Cov-2 Pandemic
        date: 2020-05-02
       words: 2266
      flesch: 43
     summary: It is predominantly people greater than 70 years of age and individuals with chronic conditions who are at risk of developing severe Covid-19 disease [11] . mBio The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus Breakthrough: chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults Population-based simulations of influenza pandemics: validity and significance for public health policy Use of rapid online surveys to assess people's perceptions during infectious disease outbreaks: a cross-sectional survey on COVID-19 Requirements and design of the PROSPER protocol for implementation of information infrastructures supporting pandemic response: a Nominal Group study Monitoring the COVID-19 epidemic in the context of widespread local transmission Coronavirus disease (COVID-19) advice for the public.
    keywords: cov-2; covid-19; disease; health; pandemic; sars; sports
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        item: #6334 of 7819
          id: cord-337436-3xzgv370
      author: Khider, Lina
       title: Curative anticoagulation prevents endothelial lesion in COVID‐19 patients
        date: 2020-06-18
       words: 1778
      flesch: 38
     summary: Coagulopathy was also found in fatal cases of COVID-19 patients, including a significant higher 23 proportion of patients with D-dimers above 500 ng/mL and prolonged prothrombin time (PT) in 24 non-survivors (7). The hypothesis of microthrombi in kidney was 26 also suggested in COVID-19 patients since high creatinine level was correlated with D-dimers 27 above 500 ng/mL (9) .
    keywords: cecs; covid-19; patients; sars; study
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        item: #6335 of 7819
          id: cord-337452-zql4zhyk
      author: Corral, L.
       title: GLUCOCOVID: A controlled trial of methylprednisolone in adults hospitalized with COVID-19 pneumonia
        date: 2020-06-18
       words: 4413
      flesch: 47
     summary: https://doi.org/10.1101/2020.06.17.20133579 doi: medRxiv preprint Kaplan-Meier plots showing the probability of not occurring the primary composite endpoint (ICU admission, need of NIV or death) of patients in the control group (grey), randomized MP group (red) and preference MP group (green), stratified by age. This trial would have been impossible without the support and collaboration of the hundreds of health professionals involved in the care of COVID-19 patients in our hospitals during the 2020 Spring pandemic.
    keywords: covid-19; group; medrxiv; patients; preprint; review; risk
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        item: #6336 of 7819
          id: cord-337456-fl5w81sp
      author: Sperotto, Francesca
       title: Unplanned and medical admissions to pediatric intensive care units significantly decreased during COVID-19 outbreak in Northern Italy
        date: 2020-10-18
       words: 2210
      flesch: 42
     summary: The number of PICU admissions significantly decreased during the COVID-19 outbreak compared to pre-COVID-19 and compared to the same period in 2020 (IRR-1 0.63 Here, we sought to evaluate the impact of the COVID-19 outbreak and lockdown measures on rates and types of PICU admissions in Northern Italy.
    keywords: admissions; covid-19; data; period; picu
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        item: #6337 of 7819
          id: cord-337460-60blhbcq
      author: Yang, Ai-Ping
       title: Infection with SARS-CoV-2 causes abnormal laboratory results of multiple organs in patients
        date: 2020-06-01
       words: 3353
      flesch: 44
     summary: In this study, severe case patients were older, and the proportion of underlying diseases was higher compared with mild case patients. This study also confirmed the higher rates of developing lymphopenia in severe case patients than in mild case patients (99.6% vs 67.2%).
    keywords: cases; clinical; coronavirus; covid-19; laboratory; lym; nlr; patients
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        item: #6338 of 7819
          id: cord-337482-imxkpfrn
      author: Koplan, Jeffrey
       title: Maxims for a Pandemic: Time, Distance, and Data
        date: 2020-10-27
       words: 1222
      flesch: 47
     summary: I n their article, Alagoz and colleagues explored the effect of coronavirus disease 2019 (COVID-19)-related public health mandates in 3 U.S. locations-Dane County, Wisconsin; the Milwaukee metropolitan area; and New York City-using agent-based simulation models (1) . Ann Intern Med DOI: 10.7326/m20-6934 sha: doc_id: 337482 cord_uid: imxkpfrn In their article, Alagoz and colleagues explored the effect of COVID-19–related public health mandates in 3 U.S. locations.
    keywords: covid-19; mandates; pandemic; public
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        item: #6339 of 7819
          id: cord-337499-jzpgtkai
      author: Yong Choi, Sung
       title: Safe surgical tracheostomy during the COVID-19 pandemic: A protocol based on experiences with Middle East Respiratory Syndrome and COVID-19 outbreaks in South Korea
        date: 2020-06-17
       words: 4737
      flesch: 43
     summary: Several studies related to guidelines or recommendations on surgical tracheostomy for COVID-19 patients have been published. Thus, we did not use a stay suture or Björk flap during surgical tracheostomy in MERS and COVID-19 patients.
    keywords: covid-19; icu; mers; outbreak; patients; ppe; protocol; tracheostomy; transmission
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        item: #6340 of 7819
          id: cord-337530-qgv29qql
      author: Idrissi, Abdelkrim Janati
       title: Sleep quality and mental health in the context of COVID-19 pandemic and lockdown in Morocco
        date: 2020-08-12
       words: 2815
      flesch: 50
     summary: Sleep Med DOI: 10.1016/j.sleep.2020.07.045 sha: doc_id: 337530 cord_uid: qgv29qql • High prevalence of sleep disorders, anxiety, and depressive signs were found in COVID-19 pandemic and lockdown. Such false believes were presenting a risk factor of sleep disorders, anxiety, and depression.
    keywords: anxiety; depressive; disorders; sleep; symptoms
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        item: #6341 of 7819
          id: cord-337572-kx5hihnr
      author: Ludwig, Stephan
       title: Coronaviruses and SARS-CoV-2: A Brief Overview
        date: 2020-04-20
       words: 2672
      flesch: 48
     summary: E Characteristics of and important lessons from the Coronavirus Disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Available at: https:// talk.ictvonline.org/taxonomy Severe acute respiratory syndrome: identification of the etiological agent Coronavirus diversity, phylogeny and interspecies jumping Coronaviruses: an overview of their replication and pathogenesis Structural insights into coronavirus entry ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia Rates of evolutionary change in viruses: patterns and determinants RNA recombination in animal and plant viruses Cultivation of the virus of infectious bronchitis Animal coronaviruses: what can they teach us about the severe acute respiratory syndrome? Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS A new virus isolated from the human respiratory tract Recovery in tracheal organ cultures of novel viruses from patients with respiratory disease Coronaviruses as the cause of respiratory infections Identification of a novel coronavirus in patients with severe acute respiratory syndrome Hosts and sources of endemic human coronaviruses Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia MERS coronavirus: diagnostics, epidemiology and transmission China Novel Coronavirus Investigating and Research Team. Identification of severe acute respiratory syndrome in Canada Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical characteristics of Coronavirus Disease 2019 in China Management of critically ill adults with COVID-19 A trial of lopinavir-ritonavir in adults hospitalized with severe COVID-19 Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial The antiviral compound remdesivir potently inhibits RNAdependent RNA polymerase from Middle East respiratory syndrome coronavirus Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection Washington State 2019-nCoV Case Investigation Team.
    keywords: china; coronavirus; cov; cov-2; covid-19; novel; sars
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        item: #6342 of 7819
          id: cord-337581-3rmrkq1k
      author: Ramos-Morcillo, Antonio Jesús
       title: Experiences of Nursing Students during the Abrupt Change from Face-to-Face to e-Learning Education during the First Month of Confinement Due to COVID-19 in Spain
        date: 2020-07-30
       words: 6826
      flesch: 58
     summary: The current state of alarm due to the COVID-19 pandemic has led to the urgent change in the education of nursing students from traditional to distance learning. The objective of this study was to discover the learning experiences and the expectations about the changes in education, in light of the abrupt change from face-to-face to e-learning education, of nursing students enrolled in the Bachelor’s and Master’s degree of two public Spanish universities during the first month of confinement due to the COVID-19 pandemic.
    keywords: education; face; health; learning; nursing; students; teaching; time; training; year
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        item: #6343 of 7819
          id: cord-337598-86xnmxvi
      author: Gil‐Rodrigo, Adriana
       title: Ultrasound in Pregnant Women With Suspected COVID‐19 Infection
        date: 2020-08-10
       words: 743
      flesch: 42
     summary: Proposal for international standardization of the use of lung ultrasound for patients with COVID-19: a simple, quantitative, reproducible method How to perform lung ultrasound in pregnant women with suspected COVID-19 A Preliminary Study on the Ultrasonic Manifestations of Peripulmonary Lesions of Non-Critical Novel Coronavirus Pneumonia (COVID-19) Chinese Critical Care Ultrasound Study Group (CCUSG). As the authors point out, lung ultrasound (LUS) is an unquestionably useful tool for detecting lung damage in the entire population.
    keywords: lung; ultrasound
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        item: #6344 of 7819
          id: cord-337599-dyxfsojh
      author: Ahamad, Shakir
       title: Primed for Global Coronavirus Pandemic: Emerging Research and Clinical Outcome
        date: 2020-09-19
       words: 1996
      flesch: 18
     summary: Genentech Announces FDA Approval of Clinical Trial for Actemra to Treat 1093 Hospitalized Patients with Severe COVID-19 Pneumonia Effective treatment of severe COVID-19 patients with 1098 tocilizumab Meplazumab treats COVID-19 pneumonia: an open-labelled, concurrent controlled 1108 add-on clinical trial First Clinical Use of Lenzilumab to Neutralize GM-CSF in 1113 Patients with Severe COVID-19 Pneumonia A Novel Protein Drug, Novaferon, 1118 as the Potential Antiviral Drug for COVID-19 aTyr Pharma Announces Phase 2 Study of ATYR1923 in COVID-19 Patients with 1121 Severe Respiratory Complications Following FDA Acceptance of IND Application aTyr-Pharma-Announces-Phase-2-Study-of-1124 ATYR1923-in-COVID-19-Patients-with-Severe-Respiratory-Complications Following-FDA-Acceptance-of-IND-Application.html Demand for dexamethasone surges as RECOVERY trial 1037 publishes preprint World first coronavirus treatment approved for NHS use by government Coronavirus | Government approves use of dexamethasone BerGenBio starts bemcentinib dosing in ACCORD Trial Major COVID-19 drugs trial begins in Namilumab and Infliximab selected for CATALYST trial in UK Vidofludimus calcium, a next 1055 generation DHODH inhibitor for the Treatment of relapsing-remitting multiple 1056 sclerosis Receives First Regulatory Approval from German Health Authority 1059 BfArM to Initiate a Phase 2 Clinical Trial of its Selective Oral DHODH Inhibitor german-health-authority-bfarm-to-initiate-a-phase-2-clinical-trial-of-its-selective-oral-1063 dhodh-inhibitor-imu-838-in-covid-19-patients Germany's BfArM approves Covid-19 trial by Immunic Announces First Patients Dosed in its Phase 2, CALVID-1 Clinical 1068 Trial of IMU-838 in COVID-19 Austrian CoronaVirus Adaptive Clinical Trial (COVID-19) (ACOVACT)
    keywords: coronavirus; covid-19; drug; patients; sars; treatment; trial
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        item: #6345 of 7819
          id: cord-337605-s07aorzi
      author: Leow, Lowell
       title: Surgery beyond COVID‐19
        date: 2020-08-04
       words: 1176
      flesch: 53
     summary: The aggressive stance adopted by Australia and New Zealand in travel bans, social distancing and active quarantine and surveillance has flattened the curve, curtailed the spread and prevented overwhelming of healthcare systems by COVID-19 patients. Despite healthcare systems coming under siege from the surge, inspirational stories surface each day on how healthcare workers support each other and continue to deliver excellent care.
    keywords: article; covid-19; pandemic
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        item: #6346 of 7819
          id: cord-337627-1a2gpqdl
      author: Alvarado-Vasquez, Noé
       title: Could a family history of type 2 diabetes be a risk factor to the endothelial damage in the patient with COVID-19?
        date: 2020-11-06
       words: 2326
      flesch: 38
     summary: These negative effects can be associated too with an impaired expression of molecules involved in the inflammatory response and with both glucose metabolism and NO synthesis, as has been reported in the subjects with FH-DM2; paralleling the recent findings in COVID-19 patients, in whom a total of 70 inflammation-related genes that influence cell metabolism has been reported [11, 29, 30, 31, 35] . Currently, it is known that endothelial cell dysfunction is a critical event in the infection by this virus.
    keywords: covid-19; diabetes; dm2; endothelial; patients
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        item: #6347 of 7819
          id: cord-337629-rwgqkow3
      author: Casale, Manuele
       title: Could nasal irrigation and oral rinse reduce the risk for COVID-19 infection?
        date: 2020-08-15
       words: 1404
      flesch: 37
     summary: key: cord-337629-rwgqkow3 authors: Casale, Manuele; Rinaldi, Vittorio; Sabatino, Lorenzo; Moffa, Antonio; Ciccozzi, Massimo title: Could nasal irrigation and oral rinse reduce the risk for COVID-19 infection? date: 2020-08-15 journal: Int J Immunopathol Pharmacol DOI: 10.1177/2058738420941757 sha: doc_id: 337629 cord_uid: rwgqkow3 Public health measures are essential to protect against COronaVIrus Disease 2019 (COVID-19). Oral rinse with antimicrobial agents is efficacious in reducing the viral load in oral fluids.
    keywords: coronavirus; covid-19; mucosa; nasal; rinse
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        item: #6348 of 7819
          id: cord-337632-2q6gm7n3
      author: Pearman, Ann
       title: Mental Health Challenges of United States Healthcare Professionals During COVID-19
        date: 2020-08-13
       words: 4679
      flesch: 45
     summary: Personal control and aging: how beliefs and expectations matter Expect the best and prepare for the worst: anticipatory coping and preparations for Y2K A stitch in time: self-regulation and proactive coping Survey of stress reactions among health care workers involved with the SARS outbreak Self-efficacy: toward a unifying theory of behavioral change Social support provided by adolescents following a disaster and perceived social support, sense of community at school, and proactive coping Stress, coping, and resources in mothers of adults with developmental disabilities Characteristics of health care personnel with COVID-19 -United States Mental health care for medical staff in China during the COVID-19 outbreak A multinational, multicentre study on the psychological outcomes and associated physical symptoms amongst healthcare workers during COVID-19 outbreak Optimism, proactive coping and quality of life among nurses: a cross-sectional study The role of expectancy and proactive control in stress regulation: a neurocognitive framework for regulation expectation Burnout among US medical students, residents, and early career physicians relative to the general US population COVID-19: a new work-related disease threatening healthcare workers Covid-19: adverse mental health outcomes for healthcare workers General hospital staff worries, perceived sufficiency of information and associated psychological distress during the A/H1N1 influenza pandemic Managing mental health challenges faced by healthcare workers during covid-19 pandemic The relationship between coping, social support, functional disability and depression in the elderly Clinical utility of the 15-item geriatric depression scale (GDS-15) for use with young and middle-aged adults Stressors, appraisal of stressors, experienced stress and cardiac response: a real-time, real-life investigation of work stress in nurses The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus Burnout and doctors: prevalence, prevention and intervention The Adaptive Value of Feeling in Control during Midlife Sociodemographic variations in the sense of control by domain: findings from the MacArthur studies of midlife The sense of control as a moderator of social class differences in health and well-being Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019 A New Synthesis: Stress and Emotion Stress and psychological distress among SARS survivors 1 year after the outbreak Online mental health services in China during the COVID-19 outbreak The immediate psychological and occupational impact of the 2003 SARS outbreak in a teaching hospital Long-term psychological and occupational effects of providing hospital healthcare during SARS outbreak Meaning in life promotes proactive coping via positive affect: a daily diary study Heterogeneity in 10-year course trajectories of moderate to severe major depressive disorder: a danish national register-based study Age differences in reactivity to daily stressors: the role of personal control Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: a systematic review and meta-analysis The structure of coping Age differences in risk and resilience factors in COVID-19-related stress Thinking ahead and staying in the present: implications for reactivity to daily stressors COVID-19 and mental health: a review of the existing literature Anxiety disorders and risk for suicidal ideation and suicide attempts: a population-based longitudinal study of adults Understanding and addressing sources of anxiety among health care professionals during the COVID-19 pandemic Psychological distress, coping behaviors, and preferences for support among New York healthcare workers during the COVID-19 pandemic COVID 19 a challenge for emergency medicine and every health care professional Manual for the State-Trait Anxiety Inventory Decreasing the negative effects of work-related stress in unchanged working environments There have been several meta-analyses and reviews of the impact of this pandemic on HCPs internationally (Chew et al., 2020; Pappa et al., 2020; Rajkumar, 2020) , but no studies from the United States were available to be included in these studies.
    keywords: coping; covid-19; hcps; health; pandemic; stress
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        item: #6349 of 7819
          id: cord-337646-gkcm6ds0
      author: None
       title: The Federation’s Pages: WFPHA: World Federation of Public Health Associations www.wfpha.org Bettina Borisch and Marta Lomazzi, Federation’s Pages Editors
        date: 2020-09-17
       words: 2533
      flesch: 40
     summary: Diverging views on whether to prioritize human health or the economy resulted in debate, social media storms, pushback, political division, and considerable variation in intra-national enthusiasm to implement full lockdown. Environment preservation is urgent for many reasons: conservation of biodiversity, the fight against climate change, reduction of air, water and food pollution, and improvement of human health and quality of life [18] .
    keywords: coronavirus; covid-19; food; health; pandemic; transmission; water; world
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        item: #6350 of 7819
          id: cord-337663-ow1l18li
      author: Qu, Liang G.
       title: Scoping review: hotspots for COVID-19 urological research: what is being published and from where?
        date: 2020-09-09
       words: 4705
      flesch: 42
     summary: On multivariable regression, greater experience level (OR = 1.76, 95% CI 1.01-3.13) and a need to manage COVID-19 patients in the urology department (OR = 2.31, 95% CI 1.20-4.65) adversely affected the quality of their work. Ultrastructural evidence for direct renal infection with SARS-CoV-2 SARS-CoV-2 can be detected in urine, blood, anal swabs, and oropharyngeal swabs specimens No evidence of SARS-CoV-2 in semen of males recovering from COVID-19 Absence of 2019 novel coronavirus in semen and testes of COVID-19 patients No SARS-CoV-2 in expressed prostatic secretion of patients with coronavirus disease 2019: a descriptive multicentre study in China Genetic alteration, RNA expression, and DNA methylation profiling of coronavirus disease 2019 (COVID-19) receptor ACE2 in malignancies: a pan-cancer analysis ACE2 correlated with immune infiltration serves as a prognostic biomarker in endometrial carcinoma and renal papillary cell carcinoma: implication for COVID-19 Expression of ACE2, the SARS-CoV-2 receptor, and TMPRSS2 in prostate epithelial cells 2020) scRNA-seq profiling of human testes reveals the presence of the ACE2 receptor, a target for SARS-CoV-2 infection in spermatogonia The ACE2 expression in Sertoli cells and Germ cells may cause male reproductive disorder after SARS-CoV-2 Infection Multiple expression assessments of ACE2 and TMPRSS2 SARS-CoV-2 entry molecules in the urinary tract and their associations with clinical manifestations of Suppression of androgen receptor (AR)-ACE2/ TMPRSS2 axis by AR antagonists may be therapeutically beneficial for male COVID patients Effect of SARS-CoV-2 infection upon male gonadal function: a single center-based study The majority of male patients with COVID-19 present low testosterone levels on admission to Intensive Care in Hamburg, Germany: a retrospective cohort study Androgen-deprivation therapies for prostate cancer and risk of infection by SARS-CoV-2: a population-based study (n = 4532)
    keywords: cov-2; covid-19; pandemic; patients; research; sars; studies; study; urology
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        item: #6351 of 7819
          id: cord-337665-roelk7i5
      author: Bhattacharjee, Hemanga K.
       title: Emergency Surgery during COVID-19: Lessons Learned
        date: 2020-09-30
       words: 2953
      flesch: 50
     summary: Operating upon COVID-19 patients is both resource consuming and stressful for the surgeons. Although he had no known contact with COVID-19 patients but a few of his symptoms resembled that of COVID-19.
    keywords: covid-19; emergency; hospital; pandemic; patients; surgery; volvulus
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        item: #6352 of 7819
          id: cord-337670-3wq260lj
      author: Joob, Beuy
       title: Letter to the Editor: Coronavirus Disease 2019 (COVID-19), Infectivity, and the Incubation Period
        date: 2020-03-31
       words: 287
      flesch: 38
     summary: A Chinese case of novel coronavirus 2019 (COVID-19) did not show infectivity during the incubation period: based on an epidemiological survey Incubation period and other epidemiological characteristics of 2019 novel coronavirus infections with right truncation: a statistical analysis of publicly available case data The authors have no conflicts of interest associated with the material presented in this paper. key: cord-337670-3wq260lj authors: Joob, Beuy; Wiwanitkit, Viroj title: Letter to the Editor: Coronavirus Disease 2019 (COVID-19), Infectivity, and the Incubation Period date: 2020-03-31 journal: J Prev Med Public Health DOI: 10.3961/jpmph.20.065 sha: doc_id: 337670 cord_uid: 3wq260lj nan Dear Editor, We read with great interest the recent publication entitled A Chinese case of coronavirus disease 2019 (COVID-19) did not show infectivity during the incubation period: based on an epidemiological survey [1] .
    keywords: incubation
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        item: #6353 of 7819
          id: cord-337672-3a3ngzvo
      author: Barzilay, Ran
       title: Resilience, COVID-19-related stress, anxiety and depression during the pandemic in a large population enriched for healthcare providers
        date: 2020-08-20
       words: 4311
      flesch: 41
     summary: Patterns of COVID-19 related worries, rates of anxiety (GAD7 > 10, 22.2%) and depression (PHQ2 > 2, 16.1%) did not differ between healthcare providers and non-healthcare providers. For COVID-19 related worries, all main and interaction effects were investigated using mixed models to account for within-person variance across items.
    keywords: anxiety; covid-19; depression; healthcare; participants; resilience; score; worries
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        item: #6354 of 7819
          id: cord-337674-mb6ue2hl
      author: Voulgaris, Athanasios
       title: Sleep medicine and COVID-19. Has a new era begun?
        date: 2020-07-17
       words: 4545
      flesch: 39
     summary: Telemedicine in the diagnosis and treatment of sleep apnoea Adherence to Continuous Positive Airway Pressure Therapy COVID-19: community CPAP and NIV should be stopped unless medically necessary to support life Coronavirus FAQs: CPAP tips for sleep apnea patients | AASM American Academy of Sleep Medicine -Association for Sleep Clinicians and Researchers 2020 Impact of COVID-19 lockdown on adherence to continuous positive airway pressure (CPAP) by obstructive sleep apnoea patients American Academy of Sleep Medicine -Association for Sleep Clinicians and Researchers n Table 1. Based on these reports, sleep laboratories urged to cancel or defer all scheduled in-laboratory and/or home sleep studies, as well as follow-up examinations of patients who have been previously receiving any form of sleep treatment
    keywords: air; covid-19; management; pandemic; pap; patients; sars; sdb; sleep; transmission; treatment
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        item: #6355 of 7819
          id: cord-337677-ktktqs7b
      author: Pereda, R.
       title: Therapeutic effectiveness of interferon alpha 2b treatment for COVID-19 patient recovery
        date: 2020-08-04
       words: 3401
      flesch: 42
     summary: Were included patients with positive throat swab specimens by real time RT-PCR who gave informed consent and had no contraindications for IFN treatment. Both data were lower than those reported at the same time by To better address the influence of IFN treatment on CFR, we considered the clinical status of patients in the context of severity of disease, using admission to ICU as an appropriate time point to match the criterion for worsened disease.
    keywords: august; covid-19; ifn; license; medrxiv; preprint; review; version
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        item: #6356 of 7819
          id: cord-337681-579cz2tc
      author: Sk, Md Fulbabu
       title: Elucidating biophysical basis of binding of inhibitors to SARS-CoV-2 main protease by using molecular dynamics simulations and free energy calculations
        date: 2020-06-01
       words: 5900
      flesch: 43
     summary: The system pressure was monitored using a Berendsen Barostat (Berendsen et al., 1984) and kept at 1.0 bar. Subsequently, a 50 ps MD simulation with a restraint force constant of 2.0 kcal mol À1 Ð À2 acting on all solute atoms at a constant pressure of 1.0 atm was conducted using Berendsen Barostat (Berendsen et al., 1984 ) at a fixed temperature of 300 K. After 1.0 ns of an equilibration phase, the production simulation was carried for 100 ns at the NPT ensemble.
    keywords: 3cl; binding; covid-19; energy; et al; figure; inhibitors; kcal; ketoamide; mol; pro; sars
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        item: #6357 of 7819
          id: cord-337692-b89ow1mf
      author: Petti, S.
       title: Ecologic association between influenza and COVID-19 mortality rates in European countries
        date: 2020-09-11
       words: 5125
      flesch: 34
     summary: Associations between demographic, health and healthcare determinants and 3-year average crude influenza mortality rate and crude COVID-19 mortality rate (log transformed), assessed through simple regression analyses (regression coefficients; 95% confidence intervals in brackets) Influenza mortality rate COVID-19 mortality rate [48] [49] [50] . We investigated the ecologic association between influenza mortality rates and COVID-19 mortality rates in the European context.
    keywords: countries; cov-2; covid-19; influenza; mortality; population; rates; sars
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        item: #6358 of 7819
          id: cord-337700-2n9tswr8
      author: Chilimuri, Sridhar
       title: Predictors of Mortality in Adults Admitted with COVID-19: Retrospective Cohort Study from New York City
        date: 2020-07-08
       words: 2356
      flesch: 47
     summary: Very limited data is available to determine risk factors and their association with outcomes in COVID-19 patients, to help hospitals and providers in triaging and managing these patients more efficiently. Microembolic disease appears to be a major contributor of death in COVID-19 patients.
    keywords: admission; covid-19; disease; hospital; patients; study
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        item: #6359 of 7819
          id: cord-337720-kmwft059
      author: Closson, Kalysha
       title: When Home is Not a Safe Place: Impacts of Social Distancing Directives on Women Living with HIV
        date: 2020-06-02
       words: 1743
      flesch: 35
     summary: As the health care system, and HIV care, may be the first line of violence support for many women living with HIV, during these unprecedented times, it is especially important that HIV care providers take a women-centred trauma-aware approach, which is led by the needs and priorities of their patients [21, 22] . As HIV care, research participation, and workplace settings are being transitioned to virtual and telephone-based methods, women living with HIV experiencing violence are less able to connect to critical social and protective networks [18] .
    keywords: covid-19; hiv; ipv; violence; women
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        item: #6360 of 7819
          id: cord-337727-i0urwkcj
      author: Aloysius, Mark M.
       title: COVID-19 presenting as acute pancreatitis
        date: 2020-05-08
       words: 253
      flesch: 29
     summary: COVID-19 pathogenesis is thought to be mediated by angiotensin-converting enzyme-2 (ACE-2) receptor on the host cells, which are highly expressed in the pancreatic islets (4) Although clear pathogenesis is unknown, AP in COVID19 could occur due to the direct cytopathic effect of local SARS-CoV-2 replication or indirectly by harmful immune response induced by the virus. Pancreatitis and cholecystitis in primary acute symptomatic Epstein-Barr virus infection -Systematic review of the literature Clinical Characteristics of Coronavirus Disease 2019 in China COVID-19 and gastrointestinal endoscopies: current insights and emergent strategies Pancreatic injury patterns in patients with COVID-19 pneumonia Isolation and characterization of a coronavirus from pigeons with pancreatitis Pancreatitis and Systemic Coronavirus Infection in a Ferret (Mustela putorius furo)
    keywords: covid-19
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        item: #6361 of 7819
          id: cord-337751-ccf8w06i
      author: Villalobos Dintrans, Pablo
       title: It Is Not Just Mortality: A Call From Chile for Comprehensive COVID-19 Policy Responses Among Older People
        date: 2020-07-07
       words: 3491
      flesch: 47
     summary: Chile has the highest testing rate in the Latin American region, with almost 1 million tests carried out by June 23 (Gobierno de Chile, 2020a; Institute of Health Metrics and Evaluation, 2020). This is particularly important in Chile, a country with a relatively high burden of disease due to mental conditions and low access to health care services (Vicente et al., 2016) .
    keywords: care; chile; country; covid-19; health; ltc; people; services; social
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        item: #6362 of 7819
          id: cord-337760-joti9nwg
      author: Buldú, Javier M.
       title: The resumption of sports competitions after COVID-19 lockdown: The case of the Spanish football league
        date: 2020-06-04
       words: 5278
      flesch: 48
     summary: Asymptomatic infectious players (belonging to class I, but not detected by virus tests), and confined infectious players, overcome the disease with probability γ. The days between virus tests N test and the days between matches N match are two critical variables for controlling the number of infected players during the championship, and therefore their influence in the model should be studied carefully.
    keywords: days; infected; match; model; number; players; probability; time
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        item: #6363 of 7819
          id: cord-337763-kusqyumn
      author: Alves, T. H. E.
       title: Underreporting of death by COVID-19 in Brazil's second most populous state
        date: 2020-05-23
       words: 2800
      flesch: 51
     summary: In conclusion, there is an underreporting of COVID-19 deaths in MG due to the unexplained excess of SARS deaths, Respiratory insufficiency and pneumonia compared to previous years. The important increase in SARS deaths that started earlier than those from COVID-19, in epidemiological week 10, is also highlighted, suggesting the underreporting of COVID-19 deaths in the state of Minas Gerais.
    keywords: covid-19; deaths; funder; license; medrxiv; perpetuity; preprint
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        item: #6364 of 7819
          id: cord-337785-fwo0r4bb
      author: Mercer, Scott Thomas
       title: A Comparative Study Looking at Trauma and Orthopaedic Operating Efficiency in the COVID-19 Era
        date: 2020-10-21
       words: 2302
      flesch: 51
     summary: Timing data was collated to look at the following: anaesthetic preparation time, anaesthetic time, surgical preparation time, surgical time, transfer to recovery time and turnaround time. A statistically significant increase in all timings was demonstrated in 2020 apart from anaesthetic time which demonstrated a significant decrease.
    keywords: anaesthetic; covid-19; data; efficiency; surgery; time
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        item: #6365 of 7819
          id: cord-337789-pabaoiqs
      author: Oprinca, George-Călin
       title: Postmortem examination of three SARS-CoV-2-positive autopsies including histopathologic and immunohistochemical analysis
        date: 2020-08-27
       words: 5012
      flesch: 43
     summary: The sectioned surface had small areas of a more intense reddish color between stretched areas of dark purple color. The gastric mucosa was hyperemic with small areas of diffuse hemorrhage.
    keywords: alveolar; areas; blood; case; cells; cov-2; death; lung; sars
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        item: #6366 of 7819
          id: cord-337796-6qs6m7h7
      author: Della Rosa, Asia
       title: What does COVID‐19 distract us from? A migration studies perspective on the inequities of attention
        date: 2020-05-18
       words: 281
      flesch: 52
     summary: In our spaces of exclusion from wealth and rights, now absent from public discourse, it is in the camps where COVID-19 will be most deadly (Oishi and Alam 2020) , and yet migrants themselves are already being constructed as potential public health risks. Why don't health care frontline professionals do more for segregated Roma?
    keywords: health; spaces
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        item: #6367 of 7819
          id: cord-337813-r9okti1v
      author: Wiwanitkit, Viroj
       title: Delay and Differential Diagnosis and Screening for Symptoms of COVID-19
        date: 2020-06-15
       words: 277
      flesch: 42
     summary: Therefore, there is no doubt that preoperative screening is useful in the current COVID-2019 pandemic. Beware of time delay and differential diagnosis when screening for symptoms of COVID-19 in surgical cancer patients Carpal fracture and COVID-19 infection: observation from Thailand 2020 by the American College of Surgeons
    keywords: screening
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        item: #6368 of 7819
          id: cord-337818-mhmc3ts8
      author: Majek, O.
       title: Modelling the first wave of the COVID-19 epidemic in the Czech Republic and the role of government interventions
        date: 2020-09-11
       words: 1701
      flesch: 35
     summary: [2] In the Czech Republic, first COVID-19 cases were confirmed on 1 March 2020. More than 27 million of COVID-19 cases and over 800 thousand deaths have been reported globally so far.
    keywords: cases; covid-19; number; preprint
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        item: #6369 of 7819
          id: cord-337831-f408yix9
      author: Prince, David S
       title: The impact of the COVID‐19 pandemic on gastroenterology trainees in Australia
        date: 2020-06-23
       words: 435
      flesch: 39
     summary: Coronavirus (COVID-19) current situation and case numbers Considerations for Australian endoscopy units during the COVID19 pandemic. key: cord-337831-f408yix9 authors: Prince, David S; Liu, Ken; Pavendranathan, Gokulan; Strasser, Simone I; Bollipo, Steven; Kanazaki, Ria title: The impact of the COVID‐19 pandemic on gastroenterology trainees in Australia date: 2020-06-23 journal: J Gastroenterol Hepatol DOI: 10.1111/jgh.15159 sha: doc_id: 337831 cord_uid: f408yix9 nan We would like to formally acknowledge the Australian gastroenterology advanced trainees who took part in this survey to participate.
    keywords: covid-19; training
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        item: #6370 of 7819
          id: cord-337837-5uynih1y
      author: Nowakowski, Alexandra C H
       title: Brave New Lungs: Aging in the Shadow of COVID-19
        date: 2020-08-07
       words: 2697
      flesch: 43
     summary: Newer lung fibrosis patients may need time to figure out what their needs and preferences even are in these areas (Kalluri et al., 2020) . Recent research in radiology suggests that severe COVID-19 does indeed produce lung fibrosis that mimics the characteristics of CF and other progressive diseases requiring extensive lifelong respiratory management .
    keywords: aging; covid-19; fibrosis; lung; patients; people
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        item: #6371 of 7819
          id: cord-337842-q03884i9
      author: Iaboni, Andrea
       title: Achieving Safe, Effective and Compassionate Quarantine or Isolation of Older Adults with Dementia in Nursing Homes.
        date: 2020-05-04
       words: 1961
      flesch: 41
     summary: In Ontario, the most recent data shows a 19% case fatality rate in nursing home residents (2) . Isolating and screening nursing home residents based on symptoms alone would fail to identify approximately half of residents with COVID-19 (7) .
    keywords: covid-19; dementia; homes; nursing; residents
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        item: #6372 of 7819
          id: cord-337878-hiylqqie
      author: Namasivayam, Abirami
       title: Atypical case of COVID-19 in a critically unwell 5-week old infant
        date: 2020-09-14
       words: 2525
      flesch: 44
     summary: Similarly, the distinguishing biochemical abnormalities associated with COVID-19 positive patients, specifically leucopenia 9 and significantly elevated CRP, 10 were not observed in our case. This case demonstrates the need for vigilance in considering COVID-19 infection in infants presenting with less discriminatory symptoms such as lethargy or reduced feeding.
    keywords: case; children; coronavirus; covid-19; infants; patient; ventilation
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        item: #6373 of 7819
          id: cord-337896-mct29erg
      author: Kornbluth, Asher
       title: Management of Inflammatory Bowel Disease and COVID-19 in New York City 2020: The Epicenter of IBD in the First Epicenter of the Global Pandemic
        date: 2020-09-03
       words: 5119
      flesch: 50
     summary: Our extensive experience in caring for IBD patients with COVID-19 stems from our practice in which we have a very large IBD patient population of Ashkenazi Orthodox and Hasidic Jews that comprises nearly 75% of our cohort. SECURE-IBD Database Public Data Update New York Times Corona Virus Map and Cases Count COVID-19 (Coronavirus): What IBD Patients Should Know BSG) advice for management of inflammatory bowel diseases during the COVID-19 pandemic AGA clinical practice update on management of inflammatory bowel disease during the COVID-19 pandemic: expert commentary IOIBD COVID-19 Webinars and Guidelines.
    keywords: cov-2; covid-19; disease; ibd; new; nyc; office; patients; practice; sars; visits
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        item: #6374 of 7819
          id: cord-337898-ncrbd8rp
      author: Pal, Rimesh
       title: Comment on “Is the type of diabetes treatment relevant to outcome of COVID‐19?”
        date: 2020-05-27
       words: 1080
      flesch: 37
     summary: The concept of harnessing the pleiotropic antiinflammatory properties of anti-diabetic medications in management of early/advanced COVID-19 in people with diabetes mellitus (DM) is intriguing. Pioglitazone improves glucose metabolism and modulates skeletal muscle TIMP-3-TACE dyad in type 2 diabetes mellitus: a randomised, double-blind, placebo-controlled, mechanistic study Should anti-diabetic medications be reconsidered amid COVID-19 pandemic?
    keywords: covid-19; diabetes; patients
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        item: #6375 of 7819
          id: cord-337906-qis8h3r3
      author: Suresh Kumar, Vishnu Charan
       title: Transaminitis is an indicator of mortality in patients with COVID-19: A retrospective cohort study
        date: 2020-09-27
       words: 3093
      flesch: 48
     summary: The existing literature points towards diarrhea as the most common GI complaint in COVID-19 patients [6, 7, 9, 10] . AIM: To describe the demographic and clinical characteristics of COVID-19 positive patients and study the association between transaminitis and all-cause mortality.
    keywords: coronavirus; covid-19; patients; study; transaminitis
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        item: #6376 of 7819
          id: cord-337917-vvvo5t4h
      author: Tempe, Dr. Deepak K.
       title: Challenges in Preparing and managing the critical care services for a large urban area during COVID-19 outbreak: Perspective from Delhi
        date: 2020-05-26
       words: 3395
      flesch: 57
     summary: In Delhi, there is a perpetual shortage of ICU beds, therefore, the biggest challenge was to create sufficient ICU beds for an anticipated surge of Covid-19 patients during the next few weeks. The main challenges faced among others were, estimating the number of ICU beds to be created; deciding the dedicated Covid hospitals; procurement of ventilators, personal protection equipment and other related material; mobilizing the human resource and their training; and providing isolated in-house accommodation to the staff on duty.
    keywords: beds; care; covid-19; delhi; hospitals; icu; patients
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        item: #6377 of 7819
          id: cord-337926-6ddvqowr
      author: Farrell, Sarah
       title: Recommendations for the Care of Pediatric Orthopaedic Patients During the COVID Pandemic
        date: 2020-04-14
       words: 3107
      flesch: 41
     summary: These guidelines, based on expert opinion and best available evidence, provide a framework for the management of pediatric orthopaedic patients during the COVID pandemic. The authors would also like to thank Wendy Krishnaswamy, RN, for providing her valued perspective from a nursing standpoint on orthopaedic patient management and consideration of patient families.
    keywords: covid; healthcare; management; orthopaedic; pandemic; patients; surgeons; treatment
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        item: #6378 of 7819
          id: cord-337946-qpa6tk6v
      author: Hsu, C.-Y.
       title: Efficacy of remdesivir in COVID-19 patients with a simulated two-arm controlled study
        date: 2020-05-08
       words: 2552
      flesch: 45
     summary: https://doi.org/10.1101/2020.05.02.20088559 doi: medRxiv preprint While the recent study on the compassionate use of remdesivir for COVID-19 patients has shown a 68% clinical improvement 7 https://doi.org/10.1101/2020.05.02.20088559 doi: medRxiv preprint The daily rate of transition between risk states, discharge, and death were estimated and analyzed by applying a continuous-time Markov model 8 Monte Carlo (MCMC) simulation in the light of likelihood functions based on aggregated data as shown in Table 1 .
    keywords: group; license; preprint
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        item: #6379 of 7819
          id: cord-337958-472xu87g
      author: Zuberi, Maaz K.
       title: SHOULD I BE CONCERNED? SURGICAL TRAINING IN THE TIME OF COVID19
        date: 2020-10-15
       words: 2994
      flesch: 40
     summary: It is clear that safeguards need to be in place to prevent surgical residents from facing financial and educational hardship during this time. As junior surgical residents working in these unique circumstances, unlike our medical colleagues who are bearing the brunt of managing the COVID outbreak, we seem to be looking at it from a distance.
    keywords: covid-19; pandemic; program; research; residents; trainees; training
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        item: #6380 of 7819
          id: cord-337965-z39q8ebq
      author: Kvernland, Alexandra
       title: Anticoagulation use and Hemorrhagic Stroke in SARS-CoV-2 Patients Treated at a New York Healthcare System
        date: 2020-08-24
       words: 3755
      flesch: 32
     summary: Moreover, there are limited data on the incidence of hemorrhagic stroke patients with COVID- 19. Larger studies are needed to further validate the clinical characteristics we found significant and further studies to evaluate the risks and benefits of therapeutic anticoagulation in stroke patients with COVID-19.
    keywords: anticoagulation; controls; covid-19; diagnosis; hemorrhagic; patients; stroke; study; time
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        item: #6381 of 7819
          id: cord-337995-z4rcczki
      author: Moris, Dimitrios
       title: Kidney Transplant Recipients Infected By COVID‐19: Review of the Initial Published Experience
        date: 2020-07-23
       words: 2738
      flesch: 33
     summary: Regarding radiographic findings in KTx COVID-19 patients, 78.5% presented with bilateral ground glass opacities in both chest plain radiograph and CT-scan of the chest 18, 19, 21-28, 30-34, 36-42, 44, 46-54 . All rights reserved A novel coronavirus outbreak of global health concern Challenges in Abdominal Organ Transplantation During the COVID-19 Pandemic Coronavirus breakthrough: dexamethasone is first drug shown to save lives Tocilizumab's efficacy in COVID-19 patients is determined by the presence of cytokine storm COVID-19 in solid organ transplantation patients: A systematic review Evidence Supporting Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 While Presymptomatic or Asymptomatic COVID-19 in solid organ transplant recipients:
    keywords: article; covid-19; kidney; ktx; patients; recipients; transplant
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        item: #6382 of 7819
          id: cord-338001-jig46hsk
      author: Ong, Jacqueline S. M.
       title: Coronavirus Disease 2019 in Critically Ill Children: A Narrative Review of the Literature
        date: 2020-04-21
       words: 3420
      flesch: 43
     summary: One or more caregivers usually accompany pediatric patients and this too needs to be taken into account when considering the care of COVID-19 patients. Children do not appear to account for a large proportion of COVID-19 disease.
    keywords: care; children; coronavirus; covid-19; disease; hospital; patients; sars; staff
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        item: #6383 of 7819
          id: cord-338005-kbkvk94k
      author: Deng, Qing
       title: Semiquantitative lung ultrasound scores in the evaluation and follow-up of critically ill patients with COVID-19: a single-center study
        date: 2020-07-14
       words: 4116
      flesch: 49
     summary: However, there have been only a few case reports of bedside LUS application in critical patients with COVID-19 (15) (16) (17) . Therefore, we chose the 8-zone protocol recommended for critical patients by the World Interactive Network Focused on Critical UltraSound (WINFOCUS).
    keywords: chest; covid-19; lung; lus; patients; scores; type; ultrasound
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        item: #6384 of 7819
          id: cord-338006-z7j6qsjs
      author: Ramos-Martínez, Antonio
       title: Hospital-acquired infective endocarditis during Covid-19 pandemic
        date: 2020-07-30
       words: 2336
      flesch: 34
     summary: Bacterial and fungal infections in COVID-19 patients: A matter of concern Impact of the global COVID-19 outbreak on the management of other communicable diseases The Use of Bronchoscopy during the COVID-19 Pandemic: CHEST/AABIP Guideline and Expert Panel Report Response of a European surgical department to the COVID-19 crisis Echocardiography during the coronavirus disease 2019 (COVID-19) pandemic: expert opinion of the Working Group on Echocardiography of the Polish Cardiac Society Barriers and facilitators to healthcare workers' adherence with infection prevention and control (IPC) guidelines for respiratory infectious diseases: a rapid qualitative evidence synthesis. As COVID-19 patient rooms were progressively established, we moved from nursing patients in single rooms before the pandemic toutilizing cohort bays as incidence of COVID-19 rose.
    keywords: cases; covid-19; endocarditis; haie; patients; study
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        item: #6385 of 7819
          id: cord-338023-gb5jgqcg
      author: Obara, Shinju
       title: Anesthesiologist behavior and anesthesia machine use in the operating room during the COVID-19 pandemic: awareness and changes to cope with the risk of infection transmission
        date: 2020-08-27
       words: 2823
      flesch: 32
     summary: The effects of such measures even in COVID-19 patients should be studied in the future. APSF/ASA Guidance on Purposing Anesthesia Machines as ICU Ventilators A process for daily checks when using anaesthetic machines to ventilate the lungs of COVID-19 patients: the 'domino switch' technique Remote control and monitoring of Ge Aisys anesthesia machines repurposed as intensive care unit ventilators Shared ventilation: toward safer ventilator splitting in resource emergencies International guidelines and recommendations for surgery during Covid-19 pandemic: a systematic review Air contamination with SARS-CoV-2 in the operating room Human papillomavirus DNA in surgical smoke during cervical loop electrosurgical excision procedures and its impact on the surgeon Electrocautery, diathermy, and surgical energy devices: are surgical teams at risk during the COVID-19 pandemic?
    keywords: anesthesia; cov-2; covid-19; infection; patients; sars; use
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        item: #6386 of 7819
          id: cord-338024-8kq5nzv5
      author: Lee, Sokbae
       title: Sparse HP filter: Finding kinks in the COVID-19 contact rate()
        date: 2020-09-26
       words: 7359
      flesch: 70
     summary: We now turn to sup f ∈F T −1 T t=1 f t u t . The marginal convergence is straightforward since f t u t is an mds with bounded second moments due to the LLN for mds.
    keywords: contact; filter; rate; time; trend
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        item: #6387 of 7819
          id: cord-338039-mxky1ai7
      author: Abu-Rayash, Azzam
       title: Analysis of mobility trends during the COVID-19 Coronavirus Pandemic: Exploring the impacts on global aviation and travel in selected cities
        date: 2020-07-16
       words: 3971
      flesch: 49
     summary: As road and air transportation worldwide started to halt, Chinese transportation sector was revived. The decline on transportation demand, consequently, translates to reduction in energy and fuel demand.
    keywords: cities; city; covid-19; demand; emissions; mobility; sector; transportation
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        item: #6388 of 7819
          id: cord-338049-en9ktl4s
      author: Naarding, P.
       title: COVID-19: clinical challenges in Dutch Geriatric Psychiatry
        date: 2020-05-27
       words: 1492
      flesch: 51
     summary: Many aspects of mental health care facilities make older patients with psychiatric disorders susceptible to the rapid spread of COVID-19 Case B -In the long-stay ward for older patients, Mrs. B, an 83-year old woman, was admitted 7 months ago after the death of her husband.
    keywords: care; case; covid-19; health
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        item: #6389 of 7819
          id: cord-338079-udybki7w
      author: Hughes, Christopher
       title: Cerebral Venous Sinus Thrombosis as a Presentation of COVID-19
        date: 2020-04-29
       words: 1010
      flesch: 46
     summary: This is the first report of CVST as a presenting symptom of COVID-19 infection. These are partially attributed to systemic inflammation and coagulopathy in patients with COVID-19 infection.
    keywords: covid-19; patients; thrombosis
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        item: #6390 of 7819
          id: cord-338086-87wfjiqm
      author: Rueda-Garrido, Juan Carlos
       title: Return to work guidelines for the COVID-19 pandemic
        date: 2020-06-01
       words: 1384
      flesch: 39
     summary: Return to work guideline for higher risk workers with COVID-19. This group includes essential workers such as healthcare workers (physicians, nurses, hospital laboratory technicians and other healthcare workers) or public safety workers (police, fire and ambulance).
    keywords: covid-19; return; risk; work; workers
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        item: #6391 of 7819
          id: cord-338090-8uu8kl9v
      author: Liao, Jie‐lan
       title: Clinical differences in chest CT characteristics between the progression and remission stages of patients with COVID‐19 pneumonia
        date: 2020-10-17
       words: 3526
      flesch: 46
     summary: CT features were recorded, such as the lesion lobe, distribution characteristics (subpleural, scattered, or diffused), shape of the lesion, maximum size of the lesion, lesion morphology (ground‐glass opacity, GGO), and consolidation features. In addition, the follow-up time of absorption was limited, and further recovery of lung function and CT remission features are unclear.
    keywords: consolidation; covid-19; features; progression; remission; sign; stage
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        item: #6392 of 7819
          id: cord-338097-kdrq81w5
      author: Brescia, Marilia D'Elboux Guimarães
       title: “Green July” 2020 and Another Good Reason to Quit Smoking: Help to Stop Spreading SARS-COV-2 and Save Lives!
        date: 2020-10-20
       words: 1206
      flesch: 57
     summary: Smoking is a well recognized risk factor for the development of head and neck cancer, and smoking cessation is the best recommended strategy to lessen the risk of upper aerodigestive tract and other cancers. SARS-Cov-2 infection in head neck cancer patients with active disease is a great threat due to cancer immunosuppression, but it is also a great risk to some survivors such as laryngectomized patients, who theoretically have a higher risk of severe infections due to inhaling aerosols more easily.
    keywords: head; neck; risk; smoking
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        item: #6393 of 7819
          id: cord-338131-6y96eyoq
      author: Galvez, A.
       title: Perforated Marginal Ulcer in a COVID-19 Patient. Laparoscopy in these Trying Times?
        date: 2020-05-24
       words: 1335
      flesch: 44
     summary: Despite current surgical recommendations [1] advising against routine laparoscopy in COVID-19 patients for aerosolization concerns; a laparoscopic approach was decided given availability of laparoscopic high-efficiency particulate air (HEPA) filters (PlumePort® ActiV®. Recent reports of poor outcomes in COVID-19 patients undergoing extensive open abdominal surgery [2] were also taken into account.
    keywords: approach; covid-19; day; management; patient
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        item: #6394 of 7819
          id: cord-338140-p88fgojk
      author: Cervantes-Pérez, Enrique
       title: Medical Nutrition Therapy in Hospitalized Patients With SARS-CoV-2 (COVID-19) Infection in a Non-critical Care Setting: Knowledge in Progress
        date: 2020-10-30
       words: 3972
      flesch: 39
     summary: This is because selenium could assist a group of enzymes that, in concert with vitamin E, work to prevent the formation of free radicals and prevent oxidative damage to cells and tissues Vitamin E is a lipid-soluble vitamin that plays an important role in reducing oxidative stress by binding to free radicals as an antioxidant.
    keywords: cells; coronavirus; covid-19; immune; infection; iron; malnutrition; patients; sars; vitamin
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        item: #6395 of 7819
          id: cord-338143-2v4lrlcl
      author: Pana, T. A.
       title: Number of International Arrivals Predicts Severity of the first Global Wave of the COVID-19 Pandemic
        date: 2020-05-16
       words: 3482
      flesch: 47
     summary: https://doi.org/10.1101/2020.05.13.20100677 doi: medRxiv preprint Whilst previous ecological studies of other epidemics have utilised case or death counts as outcome, 21 these variables may be prone to bias due to variations in country level control measures including different testing strategies, 22 variations in population movement controls and differences in secondary attack rates within community cohorts 23 . In addition, we aimed to assess the determinants for this measure by examining the association between potential country level determinants driven by hypothesis based on currently available evidence and this measure using country level publicly available data and an ecological study design.
    keywords: countries; country; covid-19; data; mortality; population; preprint
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        item: #6396 of 7819
          id: cord-338145-al2m9lou
      author: Wolka, Eskinder
       title: Awareness Towards Corona Virus Disease (COVID-19) and Its Prevention Methods in Selected Sites in Wolaita Zone, Southern Ethiopia: A Quick, Exploratory, Operational Assessment
        date: 2020-10-28
       words: 4998
      flesch: 50
     summary: (Male participant, aged 30) Two of the participants noted that the disease is the result of the anger of God since people do not obey the rule of God and one of the participants who is a bajaj driver explained that; what I know is, it is the disease that came from God as result of our bad and evil acts, it has no drug to treat and the only option is pray to God to be protected from this type of disease. Study participants deserve special acknowledgment for all their cooperation in the data collection process and for providing genuine information that resulted in the accomplishment of this assessment.
    keywords: awareness; covid-19; disease; hand; health; participants; people; prevention; study
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        item: #6397 of 7819
          id: cord-338189-j4hnldk4
      author: Saadat, Saeida
       title: Environmental perspective of COVID-19
        date: 2020-08-01
       words: 3977
      flesch: 54
     summary: For instance, in Hong Kong, where COVID-19 infection started in late January/2020 the medical wastes have already polluted the environment. Coronavirus disease 19 (COVID-19): implications for clinical dental care Presumed asymptomatic carrier transmission of COVID-19 Pneumonia of unknown aetiology in Wuhan, China: potential for international spread via commercial air travel Remdesivir for severe acute respiratory syndrome coronavirus 2 causing COVID-19: an evaluation of the evidence The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Comparison of air quality in some of the biggest cities around the world before the COVID-19 pandemic and while the lockdown Climate Affects Global Patterns of COVID-19 Early Outbreak Dynamics Coagulation disorders in coronavirus infected patients:
    keywords: china; coronavirus; covid-19; health; outbreak; pandemic; people
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        item: #6398 of 7819
          id: cord-338203-le5lbw5y
      author: O’Reilly, GM
       title: Epidemiology and clinical features of emergency department patients with suspected COVID‐19: Results from the first month of the COVED Quality Improvement Project (COVED‐2).
        date: 2020-06-13
       words: 2850
      flesch: 46
     summary: Health services and general practicecoronavirus disease (COVID-19) Informing emergency care for COVID-19 patients: The COVID-19 Emergency Department Quality Improvement Project protocol Research Electronic Data Capture (REDCap) -A metadata-driven methodology and workflow process for providing translational research informatics support Epidemiology and clinical features of emergency department patients with suspected COVID-19: Initial results from the COVID-19 Emergency Department Quality Improvement Project (COVED-1) Emergency Medicine's COVID Future: facing the triple challenge after flattening the curve Locked-down lives drive emergency department numbers to record lows. Although it was not the primary intent of the project, COVED is adding value by providing information around the current burden of suspected COVID-19 patients in the hospital system.
    keywords: cov-2; covid-19; data; patients; sars; study
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        item: #6399 of 7819
          id: cord-338205-sy91rnse
      author: Li, Chenxi
       title: Laboratory Diagnosis of Coronavirus Disease-2019 (COVID-19)
        date: 2020-07-02
       words: 7542
      flesch: 45
     summary: A data-driven analysis in the early phase of the outbreak High Contagiousness and Rapid Spread of Severe Acute Respiratory Syndrome Coronavirus 2 World Health Organization, Consensus document on theepidemiology of severe acuterespiratory syndrome (SARS) Virology, Epidemiology, Pathogenesis, and Control of COVID-19 Aerosol and Surface Distribution of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospital Wards Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes Detectable 2019-nCoV viral RNA in blood is a strong indicator for the further clinical severity First Case of 2019 Novel Coronavirus in the United States World Health Organization, Laboratory testing for 2019 novel coronavirus (2019-nCoV) in suspected human cases A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Identification of Coronavirus Isolated from a Patient in Korea with COVID-19 Quantitative Detection and Viral Load Analysis of SARS-CoV-2 in Infected Patients Transmission of 2019-nCoV Infection from an Asymptomatic Contact in Germany A new coronavirus associated with human respiratory disease in China Clinical Characteristics of Coronavirus Disease 2019 in China SARS-CoV-2 can be detected in urine, blood, anal swabs, and oropharyngeal swabs specimens Consistent detection of 2019 novel coronavirus in saliva, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study Evaluating the use of posterior oropharyngeal saliva in a point-of-care assay for the detection of SARS-CoV-2 Duration of viral detection in throat and rectum of a patient with COVID-19 Ophthalmologic evidence against the interpersonal transmission of 2019 novel coronavirus through conjunctiva Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection Guidelines for Laboratory Diagnosis of Coronavirus Disease 2019 (COVID-19) in Korea Novel Coronavirus can be detected in urine, blood, anal swabs and oropharyngeal swabs samples World Health Organization, Coronavirus disease (COVID-19) technical guidance: There are currently 7 CoVs (including SARS-CoV-2) that can cause human respiratory diseases, but to date, only SARS-CoV, MERS-CoV, and SARS-CoV-2 have caused a large outbreak with high mortality.
    keywords: assay; coronavirus; cov-2; covid-19; detection; igg; patients; pcr; protein; samples; sars; sensitivity; tests
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        item: #6400 of 7819
          id: cord-338231-uni4aqxo
      author: Shi, Puyu
       title: Clinical characteristics of imported and second-generation coronavirus disease 2019 (COVID-19) cases in Shaanxi outside Wuhan, China: a multicentre retrospective study
        date: 2020-09-30
       words: 4308
      flesch: 52
     summary: The ages of severe patients were significantly older than that of non-severe patients (median, 56 years vs. 41 years, P < 0.05). Moreover, the proportion of patients aged 65 or older was higher (32.6% vs. 5.7%, P < 0.05), and the proportion of patients aged 14-30 was lower (4.3% vs. 21.6%, P < 0.05) in the group of severe patients than in non-severe patients ( Table 1) .
    keywords: cases; clinical; covid-19; median; patients; study; table; wuhan
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        item: #6401 of 7819
          id: cord-338251-r31xh0fw
      author: Assi, Tarek
       title: The management of patients with metastatic prostate cancer during the COVID-19 pandemic
        date: 2020-05-15
       words: 4127
      flesch: 42
     summary: � Multiple recommendations have been issued to optimize the therapeutic strategies of cancer patients but the current literature still lacks guidance for prostate cancer patients. This success in the mCRPC setting encouraged researchers to evaluate the role of these agents at an earlier setting in the hormone-sensitive setting which has largely changed the treatment sequencing of prostate cancer patients [24, 25] .
    keywords: agents; cancer; covid-19; docetaxel; metastatic; neutropenia; patients; prostate
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        item: #6402 of 7819
          id: cord-338279-so0hpph4
      author: Flores, Stefan
       title: “Novel Use of Telepalliative Care in a NYC Emergency Department During the COVID-19 Pandemic”
        date: 2020-08-04
       words: 873
      flesch: 41
     summary: 102 To effectively provide palliative care and facilitate GOC conversations through the use of 104 TM, the need for further protocols must be considered. Although there has been growth 105 of telemedicine services, there is a lack of robust evidence regarding outcomes from the 106 clinical application of telemedicine in palliative care, let alone TM in the ED
    keywords: care; palliative; patients
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        item: #6403 of 7819
          id: cord-338285-7rrq3o7n
      author: Sivakumar, Bellie
       title: COVID-19 and water
        date: 2020-07-09
       words: 2178
      flesch: 49
     summary: In addition to the increase in the demands for water quantity it imposes, COVID-19 also presents challenges from the perspective of water quality. Assuming that this trend will continue, at least for the foreseeable future, the additional quantity and poorer quality of wastewater will have serious effects on water quality in nearby water bodies, including rivers and lakes.
    keywords: covid-19; people; quality; spread; water
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        item: #6404 of 7819
          id: cord-338317-ro041w5l
      author: Lockhart, Sam M.
       title: When two pandemics meet: Why is obesity associated with increased COVID-19 mortality?
        date: 2020-06-29
       words: 4667
      flesch: 35
     summary: In a rodent model 214 of obesity pulmonary resistance vessels were resistant to agonist and hypoxia induced 215 vasoconstriction ex vivo compared to lean controls 50 . 109 The majority of COVID-19 patients die having required artificial ventilation for hypoxemic respiratory 110 failure due to COVID-19 pneumonia 59 .
    keywords: adipose; covid-19; insulin; lung; obesity; patients; pulmonary; resistance; risk; tissue
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        item: #6405 of 7819
          id: cord-338341-bywxb8e4
      author: Nanda, Tavish
       title: A Measured Approach to Inpatient Ophthalmologic Screening in the COVID-19 Era: A Multicenter Perspective
        date: 2020-08-07
       words: 865
      flesch: 24
     summary: 104 Emergency Room Ophthalmology Consultations at a Tertiary Care Center inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical practice guideline for the 122 management of candidiasis: 2016 update by the Infectious Diseases Society of America Utility of ophthalmologic screening for 125 patients with Candida bloodstream infections: a systematic review Do all candidemic patients need an 128 ophthalmic examination? Fungal eye disease at a 130 tertiary care center: the utility of routine inpatient consultation Outbreak of adenovirus in a neonatal intensive 133 care unit: critical importance of equipment cleaning during inpatient ophthalmologic 134 tests in the screening for lung transplantation Clinical utility of pre-transplant ophthalmic 144 consultation for lung transplant recipients: implications in the COVID-19 pandemic era Klebsiella pneumoniae, and Enterococcus faecium in hospital-acquired 148 bloodstream infections Candida auris: a rapidly emerging cause of hospital-151 acquired multidrug-resistant fungal infections globally Candida auris and endogenous 153 panophthalmitis: clinical and histopathological features New York City COVID-19 resident 156 physician exposure during exponential phase of pandemic A focused and intelligent selection for ophthalmologic screening 100 examinations based on signs and symptoms in this context is a most reasonable approach moving 101 forward, given known previous mortalities from adenoviral infection even when screening has 102 been appropriate and necessary.
    keywords: care; covid-19; screening
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        item: #6406 of 7819
          id: cord-338346-e3fk6gz2
      author: Oliveros, Estefania
       title: Coronavirus Disease 2019 and Heart Failure: A Multiparametric Approach
        date: 2020-08-14
       words: 2484
      flesch: 37
     summary: The Heart Failure Society of America (HFSA) and the Heart Failure Association of the European Society of Cardiology have ensured that HF patients are appropriately informed during the novel COVID-19 pandemic. Similarly, a joint HFSA, America College of Cardiology (ACC) and American Heart Association statement said there were no experimental or clinical data demonstrating beneficial or adverse outcomes with background use of ACE inhibitors, ARBs or other RAAS antagonists among COVID-19 patients with a history of cardiovascular disease treated with such agents.
    keywords: angiotensin; covid-19; disease; heart; pandemic; patients
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        item: #6407 of 7819
          id: cord-338359-pd4bfjet
      author: Yu, J.
       title: Risk assessment of admission procedures for cancer patients during the convalescence of COVID-19
        date: 2020-09-30
       words: 1095
      flesch: 42
     summary: Background: There are limited data on cancer patients (pts) and the novel coronavirus (SARS-CoV2) respiratory disease (COVID-19). The impact on cancer patients (pts) may be even greater.
    keywords: cancer; covid-19; patients; pts
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        item: #6408 of 7819
          id: cord-338365-9sd62a2w
      author: Patrício Silva, Ana L.
       title: Increased plastic pollution due to Covid-19 pandemic: challenges and recommendations
        date: 2020-08-17
       words: 7425
      flesch: 34
     summary: Although the absence of data on the demand/use of PPE and SUP, and subsequent increment of plastics waste and changes in waste management strategies, during the first semester of COVID-19 evolution, several reports tried to estimate their environmental footprint considering different scenarios. Production of GHG, such as CO 2 and CH 4 , is released in significant amounts during plastic waste decomposition in landfills, or during the burning of plastics waste [32] .
    keywords: bags; covid-19; disinfection; effects; environment; health; management; masks; measures; pandemic; plastic; pollution; ppe; production; public; safety; sars; use; waste
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        item: #6409 of 7819
          id: cord-338397-mbk0i13g
      author: Hadjiyiannakis, D.
       title: Personal View: Low-dose Lung Radiotherapy Should be Evaluated as a Treatment for Severe COVID-19 Lung Disease
        date: 2020-08-14
       words: 2381
      flesch: 31
     summary: Very early interim data from a US pilot trial in which older, comorbid patients with severe COVID-19 lung disease received LDRT (1.5 Gy) at standard dose rate are reassuring, with no acute deteriorations or measurable early toxicity [26] . COVID-19 lung disease exhibits an acute, hyper-inflammatory state, the severity of which correlates with morbidity and mortality
    keywords: covid-19; disease; dose; ldrt; lung; patients; radiation; radiotherapy
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        item: #6410 of 7819
          id: cord-338413-6vpfgwie
      author: Cinelli, Eleonora
       title: Teledermatology for patient management, dermatology education and research during the COVID‐19 pandemic
        date: 2020-05-14
       words: 709
      flesch: 35
     summary: Here, we would like to report our Italian experience in providing medical care and ensuring educational opportunities for medical students and dermatology residents during the COVID-19 pandemic. Dermatology residents have been organised in reduced shifts, in order to guarantee their presence where and when needed, but not exceeding the medical supply requested in view of the reduced number of visits.
    keywords: covid-19; dermatology; teledermatology
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        item: #6411 of 7819
          id: cord-338415-6tmk7l89
      author: Kihira, Shingo
       title: Neurovascular complications that can be seen in COVID-19 patients
        date: 2020-10-06
       words: 1914
      flesch: 44
     summary: SSRN Electron J 2020 Neurologic features in severe SARS-CoV-2 infection Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study COVID-19-associated acute hemorrhagic necrotizing encephalopathy: CT and MRI features COVID-19: consider cytokine storm syndromes and immunosuppression COVID-19 and its implications for thrombosis and anticoagulation Acute pulmonary embolism and COVID-19 pneumonia: a random association? Findings of acute pulmonary embolism in COVID-19 patients Acute pulmonary embolism associated with COVID-19 pneumonia detected by pulmonary CT angiography Thromboembolic risk and anticoagulant therapy in COVID-19 patients: emerging evidence and call for action Abdominal imaging findings in COVID-19: preliminary observations Noninvasive prediction of IDH1 mutation and ATRX expression loss in low-grade gliomas using multiparametric MR Radiomic features Incidence of thrombotic complications in critically ill ICU patients with COVID-19 European Journal of Case Reports in Internal Medicine European Journal of Case Reports in Internal Medicine © EFIM 2020 Arterial Mesenteric Thrombosis as a Complication of SARS-CoV-2 Infection ADULT BRAIN neurovascular complications in COVID-19 infection: case series COVID-19 is an independent risk factor for acute ischemic stroke Stroke in patients with SARS-CoV-2 infection: case series Cerebral venous sinus thrombosis as a presentation of COVID-19 COVID-19 presenting as stroke Classification of subtype of acute ischemic stroke definitions for use in a multicenter clinical trial SARS-CoV-2 and stroke in a New York healthcare system Potential mechanisms of hemorrhagic stroke in elderly COVID-19 patients ADULT BRAIN cerebral venous thrombosis associated with COVID-19 None. We believe that as COVID-19 incidence continues to grow during this pandemic, radiologists should be cognizant of these possible neurovascular complications linked to COVID-19 infection.
    keywords: covid-19; fig; infection; patients; thrombosis
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        item: #6412 of 7819
          id: cord-338416-vuu8x48x
      author: Hamer, Mark
       title: Overweight, obesity, and risk of hospitalization for COVID-19: A community-based cohort study of adults in the United Kingdom
        date: 2020-09-01
       words: 2356
      flesch: 44
     summary: Body mass index and risk of infections among women in the Danish National Birth Cohort A prospective study of age and lifestyle factors in relation to communityacquired pneumonia in US men and women Risk and protective factors related to mortality from pneumonia among middleaged and elderly community residents: The JACC study The obesity paradox in community-acquired bacterial pneumonia Obesity is associated with improved survival in community-acquired pneumonia Lifestyle risk factors, obesity and infectious disease mortality in the general population: Linkage study of 97,844 adults from England and Scotland Prevalence of obesity among adult inpatients with COVID-19 in France LICORN and the Lille COVID-19 and Obesity study group, High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission Lifestyle risk factors, inflammatory mechanisms, and COVID-19 hospitalization: A community-based cohort study of 387,109 adults in UK UK biobank: An open access resource for identifying the causes of a wide range of complex diseases of middle and old age Association of body mass index and waist-to-hip ratio with brain structure: UK Biobank study Biomarker Project: Companion document to accompany serum biomarker data COVID-19 virus testing in NHS laboratories Elevated HbA1c levels and the accumulation of differentiated T cells in CMV + individuals Obesity, metabolic health, and history of Cytomegalovirus infection in the general population Comparison of risk factor associations in UK Biobank against representative, general population based studies with conventional response rates: Prospective cohort study and individual participant meta-analysis ACKNOWLEDGMENTS. While a link between obesity and the occurrence of COVID-19 infection may be biologically plausible, to date, only prognostic studies based on small clinical samples have been conducted (7) (8) (9) .
    keywords: bmi; covid-19; data; obesity; risk; study; weight
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        item: #6413 of 7819
          id: cord-338417-7kw9lws0
      author: Singh, Awadhesh Kumar
       title: Comorbidities in COVID-19: Outcomes in hypertensive cohort and controversies with renin angiotensin system blockers
        date: 2020-04-09
       words: 3216
      flesch: 42
     summary: Although the emerging data hints to an increase in mortality in COVID-19 patients with known hypertension, diabetes and CVD, it should be noted that it was not adjusted for multiple confounding factors. Harm or benefit in COVID-19 patients receiving RASB has not been typically assessed in these studies yet, although mechanistically and plausibly both, benefit and harm is possible with these agents, given that COVID-19 expresses to tissues through the receptor of angiotensin converting enzyme-2.
    keywords: angiotensin; coronavirus; covid-19; hypertension; patients; receptor; sars
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        item: #6414 of 7819
          id: cord-338419-n8cmv8mf
      author: Carmelo, Juliana de Carvalho
       title: Impact of COVID-19 on the daily routine of radiology clinics
        date: 2020-09-16
       words: 1737
      flesch: 47
     summary: 11 With its high transmissibility and the possibility of asymptomatic carriers, COVID-19 presents a high risk of infection for dental radiology professionals, who could consequently transmit the disease to others. Consequently, many oral problems have been neglected during this period, since patients avoid social interactions and postpone important diagnostic exams.
    keywords: covid-19; disease; health; patient; transmission
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        item: #6415 of 7819
          id: cord-338436-0z828org
      author: Tzou, Philip L.
       title: Coronavirus Antiviral Research Database (CoV-RDB): An Online Database Designed to Facilitate Comparisons between Candidate Anti-Coronavirus Compounds
        date: 2020-09-09
       words: 8207
      flesch: 38
     summary: Implications for disease pathogenesis and clinical manifestation Regulation of the Interferon System: Evidence that Vero Cells have a Genetic Defect in Interferon Production Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19 Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collection Comparative analysis of antiviral efficacy of FDA-approved drugs against SARS-CoV-2 in human lung cells: Nafamostat is the most potent antiviral drug candidate Characterization and treatment of SARS-CoV-2 in nasal and bronchial human airway epithelia Replication of SARS-CoV-2 in human respiratory epithelium Replication of SARS coronavirus administered into the respiratory tract of African Green, rhesus and cynomolgus monkeys Pneumonitis and Multi-Organ System Disease in Common Marmosets (Callithrix jacchus) Infected with the Severe Acute Respiratory Syndrome-Associated Coronavirus Animal models for SARS Animal models for SARS and MERS coronaviruses Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques Cynomolgus macaque as an animal model for severe acute respiratory syndrome Respiratory disease in rhesus macaques inoculated with SARS-CoV-2 Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2 Antiviral Efficacies of FDA-Approved Drugs against SARS-CoV-2 Infection in Ferrets Infection and Rapid Transmission of SARS-CoV-2 in Ferrets Pathogenesis and transmission of SARS-CoV-2 in golden hamsters The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2 COVID-19 preclinical models: Human angiotensin-converting enzyme 2 transgenic mice Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset Type I and Type III Interferons-Induction, Signaling, Evasion, and Application to Combat COVID-19 SARS-CoV-2 sensitive to type I interferon pretreatment Coronavirus membrane fusion mechanism offers a potential target for antiviral development Coronaviruses -drug discovery and therapeutic options The Anticoagulant Nafamostat Potently Inhibits SARS-CoV-2 S Protein-Mediated Fusion in a Cell Fusion Assay System and Viral Infection In Vitro in a Cell-Type-Dependent Manner. β-D-N4hydroxycytidine-5′isopropyl ester (EIDD-2801) EIDD-2801 is a nucleoside analog, which like remdesivir has high nanomolar inhibitory activity in vitro against SARS-CoV-2 [62] .
    keywords: activity; animal; antibodies; antiviral; cell; compounds; coronavirus; cov-2; covid-19; data; drug; experiments; human; sars; trials; virus
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        item: #6416 of 7819
          id: cord-338438-q5fis2v8
      author: Young, Sean D.
       title: Clinical Care, Research, and Telehealth Services in the Era of Social Distancing to Mitigate COVID-19
        date: 2020-05-21
       words: 1446
      flesch: 34
     summary: COVID-19 will continue to impact the way that technologies are integrated into HIV clinical care and research long after the removal of social distancing policies, making it important to begin investing in the knowledge, infrastructure, and implementation of these technologies now to be prepared for the future. Findings suggest that these tools are especially impactful when delivered based on specific rather than general needs (e.g., keeping HIV patients engaged in sociallydistanced care), and on evidenced-based behavioral and social science frameworks.
    keywords: care; covid-19; hiv; patients
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        item: #6417 of 7819
          id: cord-338462-muetf7l1
      author: OKPOKORO, E.
       title: Ecologic correlation between underlying population level morbidities and COVID-19 case fatality rate among countries infected with SARS-CoV-2
        date: 2020-05-02
       words: 2744
      flesch: 47
     summary: High income countries (HIC) seemingly account for the majority of the mortalities considering that these countries have screened more persons. key: cord-338462-muetf7l1 authors: OKPOKORO, E.; IGBINOMWANHIA, V.; JEDY-AGBA, E.; KAYODE, G.; ONYEMATA, E.; ABIMIKU, A. title: Ecologic correlation between underlying population level morbidities and COVID-19 case fatality rate among countries infected with SARS-CoV-2 date: 2020-05-02 journal: nan DOI: 10.1101/2020.04.28.20082370 sha: doc_id: 338462 cord_uid: muetf7l1 Background: The ongoing Coronavirus disease 2019 (COVID-19) pandemic is unprecedented in scope.
    keywords: covid-19; license; preprint; prevalence
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        item: #6418 of 7819
          id: cord-338466-7uvta990
      author: Singh, Brijesh P.
       title: Modeling and forecasting the spread of COVID-19 pandemic in India and significance of lockdown: A mathematical outlook
        date: 2020-10-31
       words: 9014
      flesch: 50
     summary: Right now in India only 29 districts out of 739 districts have COVID-19 case more than 4000. India reported its first case on 30th January and entered the countrywide lockdown on March 24th, 2020 with constantly increase in number of COVID-19 cases.
    keywords: cases; covid-19; disease; growth; india; lockdown; model; number; population; rate; spread; time
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        item: #6419 of 7819
          id: cord-338467-7om13u87
      author: Saqlain, M.
       title: Public Knowledge and Practices regarding COVID-19: A cross-sectional survey from Pakistan
        date: 2020-06-02
       words: 3622
      flesch: 51
     summary: Of 689 participants, more than half had good knowledge; 80% had good practices regarding COVID-19 and majority seek knowledge from social media. Possible speculation of a higher rate of good practices depsite of only 50% population had good knowledge could be that of campaigns lauched by Government describing causes, symptoms, and route but these awareness campaigns primarily focused on highlighting precautionary measures such as wearing a facemask, social distancing, and hand hygiene practices.
    keywords: covid-19; knowledge; license; medrxiv; perpetuity; preprint; study
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        item: #6420 of 7819
          id: cord-338478-gkes9a16
      author: Haddad, S.
       title: Encephalopathy and seizure activity in a COVID-19 well controlled HIV patient
        date: 2020-05-16
       words: 1102
      flesch: 46
     summary: If further cases of seizure activity are reported in COVID-19 positive patients, the usefulness of prophylactic antiepileptics will need to be evaluated especially if they present with significant encephalopathy even in the absence of abnormal brain anatomy. Remdesivir was approved for compassionate use, however was not administered as patient had significant clinical improvement at that point.
    keywords: covid-19; day; patient
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        item: #6421 of 7819
          id: cord-338481-jox35yg1
      author: Tijjani, Salman Jidda
       title: Is Nigeria prepared and ready to respond to the COVID-19 pandemic in its conflict-affected northeastern states?
        date: 2020-05-27
       words: 1871
      flesch: 34
     summary: key: cord-338481-jox35yg1 authors: Tijjani, Salman Jidda; Ma, Le title: Is Nigeria prepared and ready to respond to the COVID-19 pandemic in its conflict-affected northeastern states? date: 2020-05-27 journal: Int J Equity Health DOI: 10.1186/s12939-020-01192-6 sha: doc_id: 338481 cord_uid: jox35yg1 Northeastern Nigeria has over the decade suffered from the Boko Haram insurgency and is still in the process of recovery from the complex humanitarian crisis that has displaced and subjected millions of vulnerable children, women and elderly population to poverty, disease outbreaks, hunger and malnutrition. Yet, the conflict-affected states in Northeastern Nigeria is not far away from being the worse-hit by the COVID-19 pandemic if urgent public health preventive measures are not taken to contain the spread of the deadly and highly infectious virus.
    keywords: cases; covid-19; health; nigeria; northeastern; states
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        item: #6422 of 7819
          id: cord-338493-ngvfz9dn
      author: Her, Minyoung
       title: Repurposing and reshaping of hospitals during the COVID-19 outbreak in South Korea
        date: 2020-05-05
       words: 1103
      flesch: 37
     summary: key: cord-338493-ngvfz9dn authors: Her, Minyoung title: Repurposing and reshaping of hospitals during the COVID-19 outbreak in South Korea date: 2020-05-05 journal: One Health DOI: 10.1016/j.onehlt.2020.100137 sha: doc_id: 338493 cord_uid: ngvfz9dn During the extensive outbreak of coronavirus disease 2019 (COVID-19) in South Korea, many strategies in the hospital setting, such as stratified patient care, the assignment of hospitals/beds by a task force team, and the establishment of dedicated COVID-19 hospitals, dedicated COVID-19 emergency centers, COVID-19 community facilities, and respiratory care split hospitals, were adopted to mitigate community transmission and prevent nosocomial infection. With an exponential increase in the number of COVID-19 patients, the fight against COVID-19 has now entered a new chapter.
    keywords: care; covid-19; outbreak
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        item: #6423 of 7819
          id: cord-338498-3238fz73
      author: Kleen, Thomas-Oliver
       title: Mitigating Coronavirus Induced Dysfunctional Immunity for At-Risk Populations in COVID-19: Trained Immunity, BCG and “New Old Friends”
        date: 2020-09-04
       words: 12549
      flesch: 26
     summary: bioRxiv Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals Immune responses to middle east respiratory syndrome coronavirus during the acute and convalescent phases of human infection Pathological findings of COVID-19 associated with acute respiratory distress syndrome Clonally diverse CD38(+)HLA-DR(+)CD8(+) T cells persist during fatal H7N9 disease Characterization of human CD8 T cell responses in dengue virusinfected patients from India Severe pandemic H1N1 2009 infection is associated with transient NK and T deficiency and aberrant CD8 responses Human Ebola virus infection results in substantial immune activation This is further supported by a study that screened for the presence of SARS-specific T cells in a cohort of three SARS-CoV-recovered individuals, where CD8+ T cell responses targeting the SARS-CoV membrane and nucleocapsid proteins were found to persist up to 11 years post-infection (70) .
    keywords: activation; acute; bcg; cd8; cells; coronavirus; cov-2; covid-19; disease; human; immune; immunity; infection; innate; macrophages; patients; responses; sars; study; t cells; vaccine
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        item: #6424 of 7819
          id: cord-338517-1mxcssjj
      author: Ishay, Yuval
       title: Antibody response to SARS‐Co‐V‐2, diagnostic and therapeutic implications
        date: 2020-08-26
       words: 7408
      flesch: 29
     summary: Prior to and concurrently with the isolation of specific antibodies, SARS-CoV S1-specific serum from convalescent SARS patients or from animals was proposed to cross-neutralize the SARS-CoV-2 infection by reducing S proteinmediated SARS-CoV-2 entry (30) . Convalescent plasma or immunoglobulins were effective in SARS patients whose condition continued to deteriorate.
    keywords: antibodies; antibody; cells; convalescent; coronavirus; cov-2; covid-19; disease; immune; infection; nabs; patients; plasma; response; sars
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        item: #6425 of 7819
          id: cord-338526-mn10j5i0
      author: Berg, Michael B
       title: Prevalence and predictors of early COVID-19 behavioral intentions in the United States
        date: 2020-09-07
       words: 4241
      flesch: 39
     summary: One conceptual model that has been shown to be predictive of health behavior is self-efficacy, which refers to a person's belief about their ability to regulate a given action to achieve a specific behavioral outcome [3] . Previous research has generally shown an ambiguous relationship with external locus of controlpowerful others and health behavior.
    keywords: behaviors; control; covid-19; health; participants; prevention
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        item: #6426 of 7819
          id: cord-338544-eph89g47
      author: Spuntarelli, Valerio
       title: COVID-19: is it just a lung disease? A case-based review
        date: 2020-07-28
       words: 2286
      flesch: 40
     summary: Int Forum Allergy Rhinol Guillain Barre syndrome associated with COVID-19 infection: a case report Guillain-Barré syndrome following COVID-19: new infection, old complication? COVID-19-associated acute hemorrhagic necrotizing encephalopathy: CT and MRI features Central nervous system manifestations of COVID-19: a systematic review New onset acute symptomatic seizure and risk factors in coronavirus disease 2019: a retrospective multicenter study Orchitis: a complication of severe acute respiratory syndrome (SARS)1 Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Possible involvement of infection with human coronavirus 229E, but not NL63, in Kawasaki disease COVID-19 and the liver: little cause for concern Potential pathogenesis of ageusia and anosmia in COVID-19 patients.
    keywords: acute; case; covid-19; disease; patients; sars; study; syndrome
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        item: #6427 of 7819
          id: cord-338571-1pp8v6nk
      author: Schmidt, Charles W.
       title: Lack of Handwashing Access: A Widespread Deficiency in the Age of COVID-19
        date: 2020-06-29
       words: 1005
      flesch: 46
     summary: 1, 2 A new study in Environmental Health Perspectives reports that billions of people lack access to the handwashing resources needed for protection against this and other viruses. Even some populations in wealthier countries lack access to handwashing.
    keywords: access; covid-19; handwashing; water
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        item: #6428 of 7819
          id: cord-338572-5ifc2lx6
      author: Nagarakanti, Sandhya R.
       title: Clinical outcomes of patients with COVID‐19 and HIV coinfection
        date: 2020-09-19
       words: 1599
      flesch: 48
     summary: These data points included HIV-associated characteristics such as most recent CD4+ T cells, CD4/CD8 ratio, ( obtained by flow cytometry Clinical outcomes of hospitalized patients were compared to that of a propensity matched cohort of COVID-19 patients who had no history of HIV infection. We present the clinical outcomes of HIV patients hospitalized for COVID‐19 in a matched comparison with historical controls.
    keywords: covid-19; hiv; infection; outcomes; patients
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        item: #6429 of 7819
          id: cord-338580-zszeldfv
      author: Chang, Yu-Kai
       title: Exercise Behavior and Mood during the COVID-19 Pandemic in Taiwan: Lessons for the Future
        date: 2020-09-28
       words: 6625
      flesch: 35
     summary: A cumulative link model was used to predict changes in exercise frequency during a similar future pandemic by exercise frequency during the pandemic. A linear model was used to predict the influence of exercise frequency before and during the pandemic on mood states during the pandemic.
    keywords: covid-19; days; exercise; exercise frequency; frequency; mood; pandemic; prepandemic; states
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        item: #6430 of 7819
          id: cord-338600-wpfcxnyu
      author: Stewart, Cameron
       title: Mental Capacity Assessments for COVID-19 Patients: Emergency Admissions and the CARD Approach
        date: 2020-11-09
       words: 3109
      flesch: 46
     summary: We examine the principles of mental capacity and make recommendations on how to assess the capacity of COVID-19 patients to consent to emergency medical treatment. In this article we define mental capacity, restate the legal test, and provide practical advice on how to assess the capacity of COVID-19 patients in emergency and critical care settings, including a short list of questions which flag capacity issues which we refer to as the CARD approach.
    keywords: capacity; consent; covid-19; decision; information; patients; treatment
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        item: #6431 of 7819
          id: cord-338602-6n309bnp
      author: Gadotti, Ana Carolina
       title: IFN-γ is an independent risk factor associated with mortality in patients with moderate and severe COVID-19 infection
        date: 2020-09-23
       words: 2892
      flesch: 49
     summary: Besides it, cytokine storm is also present in severe patients due to elevation of interleukins such as TNF-α, IL-6, IL-8, and IL-10 2, 3 . Lancet Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors.
    keywords: cells; covid-19; disease; ifn; levels; patients
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        item: #6432 of 7819
          id: cord-338605-3i5pvcgu
      author: Antoun, Lina
       title: Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome A prospective cohort study
        date: 2020-07-15
       words: 2331
      flesch: 48
     summary: [10] of more than 400 pregnant patients hospitalised with COVID-19 suggest an increased potential for adverse maternal outcomes in pregnant patients hospitalised with confirmed COVID-19 infection; while the risk of an intrauterine vertical transmission is inconclusive . Nasal swabs were performed to screen for COVID-19 in seven infants 7/19 (37%) who were delivered to mothers with severe symptoms (one test was not performed as guidance for not routinely performing screening test on the neonates born to COVID-19 patient was changed to routine screening soon after the data collection started).
    keywords: covid-19; infection; outcomes; patients; pregnancy
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        item: #6433 of 7819
          id: cord-338626-x0d3qlj2
      author: Etkin, Yana
       title: Acute arterial thromboembolism in patients with COVID-19 in the New York City area
        date: 2020-08-28
       words: 713
      flesch: 50
     summary: While the mechanism of thromboembolic events in patients with COVID-19 remains unclear, the occurrence of such complication is associated with acute arterial ischemia which results in a high limb loss and mortality. From the world's largest experience with COVID-19, we report the clinical presentation, While the mechanism of thromboembolic events in patients with COVID-19 remains unclear, the 102 occurrence of such complication is associated with acute arterial ischemia which results in a 103 high limb loss and mortality.
    keywords: arterial; ischemia; patients
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        item: #6434 of 7819
          id: cord-338628-7l9b5mqp
      author: Nguyen-Huynh, Mai N.
       title: Acute Stroke Presentation, Care, and Outcomes in Community Hospitals in Northern California During the COVID-19 Pandemic
        date: 2020-08-17
       words: 3266
      flesch: 55
     summary: Because of the retrospective nature of the study, we did not have direct data on stroke patients who were not presenting to the ED. There was no increase in inpatient mortality for stroke patients who were admitted and treated during the pandemic.
    keywords: alert; covid-19; pandemic; patients; post; pre; sip; stroke
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        item: #6435 of 7819
          id: cord-338633-pxxon1ni
      author: Zuo, Yu
       title: Neutrophil extracellular traps and thrombosis in COVID-19
        date: 2020-11-05
       words: 2792
      flesch: 34
     summary: SARS-CoV-2: a storm is raging Immune phenotyping based on neutrophilto-lymphocyte ratio and IgG predicts disease severity and outcome for patients with COVID-19 COVID-19 early warning score: a multi-parameter screening tool to identify highly suspected patients Advance in the management of sepsis-induced coagulopathy and disseminated intravascular coagulation New strategies for treatment of infectious sepsis Adenosine receptor agonism protects against NETosis and thrombosis in antiphospholipid syndrome In vivo role of neutrophil extracellular traps in antiphospholipid antibody-mediated venous thrombosis Ectonucleotidase tri(di)phosphohydrolase-1 (ENTPD-1) disrupts inflammasome/interleukin 1beta-driven venous thrombosis Neutrophils in the initiation and resolution of acute pulmonary inflammation: understanding biological function and therapeutic potential Immunothrombosis in acute respiratory distress syndrome: cross talks between inflammation and coagulation Neutrophil extracellular traps kill bacteria Inflammation: Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis Neutrophil extracellular traps in atherosclerosis and atherothrombosis Neutrophil extracellular traps promote deep vein thrombosis in mice In vivo characterization of neutrophil extracellular traps in various organs of a murine sepsis model Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Pandemic H1N1 influenza infection and vascular thrombosis COVID-19-associated coagulopathy: An exploration of mechanisms Neutrophil extracellular traps in COVID-19 Yost CC (2020) Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome Vascular occlusion by neutrophil extracellular traps in COVID-19 Targeting potential drivers of COVID-19: neutrophil extracellular traps Ritis K (2020)
    keywords: cell; covid-19; dna; levels; nets; neutrophil; patients; thrombosis; traps
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        item: #6436 of 7819
          id: cord-338647-dtuohsf5
      author: Başcı, Semih
       title: Outcome of COVID-19 in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitors
        date: 2020-08-27
       words: 2715
      flesch: 45
     summary: The data of 16 laboratory-confirmed COVID-19 patients with CML receiving TKI and age, gender, and comorbid disease matched COVID-19 patients without cancer at a 3/1 ratio (n = 48), diagnosed between March 11, 2020 and May 22, 2020 and included in the Republic of Turkey, Ministry of Health database, were analyzed retrospectively. The case fatality rate (CFR) in COVID-19 patients with CML was 6.3%, and it was 12.8% in the control group.
    keywords: cml; control; covid-19; group; imatinib; patients; sars
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        item: #6437 of 7819
          id: cord-338654-ma9ayu80
      author: Eaton, Lisa A.
       title: Social and behavioral health responses to COVID-19: lessons learned from four decades of an HIV pandemic
        date: 2020-04-25
       words: 3428
      flesch: 27
     summary: Trump claims public health warnings on covid-19 are a conspiracy against him A reanalysis of a behavioral intervention to prevent incident HIV infections: Including indirect effects in modeling outcomes of Project EXPLORE Stigma and conspiracy beliefs related to preexposure prophylaxis (PrEP) and interest in using PrEP among black and white men and transgender women who have sex with men Sampling hard to reach populations An information-motivation-behavioral skills model of adherence to antiretroviral therapy The novel coronavirus (COVID-2019) outbreak: Amplification of public health consequences by media exposure Stigma: Notes on the management of spoiled identity Advantages and disadvantages for receiving Internet-based HIV/AIDS interventions at home or at community-based organizations The injury iceberg: An ecological approach to planning sustainable community safety interventions A meta-analytic review of HIV behavioral interventions for reducing sexual risk behavior of men who have sex with men Institute of Medicine. These conspiracy-driven messages are all well-documented lines of thought in HIV social science research, and critically, result in harmful outcomes (Nattrass, 2012; Kalichman, 2017) .
    keywords: community; covid-19; disease; health; hiv; interventions; level; prevention
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        item: #6438 of 7819
          id: cord-338666-gg9qcpmz
      author: Rubin, Geoffrey A.
       title: Restructuring Electrophysiology During the COVID-19 Pandemic: A Practical Guide From a New York City Hospital Network
        date: 2020-04-27
       words: 4864
      flesch: 37
     summary: The aims of these recommendations are to outline: (1) essential practical steps to approaching procedures, as well as outpatient and inpatient care of EP patients, with relevant examples, (2) successful strategies to minimize exposure risk to patients and clinical staff while also balancing resource utilization, (3) challenges related to redeployment and restructuring of clinical and support staff, and (4) considerations regarding continued collaboration with clinical and administrative colleagues to implement these changes. Further staff responsibilities include designating colleagues to coordinate research efforts with Institutional Review Board and other departments on topics of more urgent COVID-related interest (e.g., QTc in the setting of COVID-19 treatment, obtaining 7-lead ECGs off telemetry in units since unable to perform frequent 12-lead ECGs on COVID-19 patients).
    keywords: care; challenges; covid-19; crisis; device; home; hospital; medical; pandemic; patients; risk; staff; system
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        item: #6439 of 7819
          id: cord-338680-wwlttymp
      author: Khonyongwa, K.
       title: Incidence and outcomes of healthcare-associated COVID-19 infections: significance of delayed diagnosis and correlation with staff absence
        date: 2020-07-30
       words: 4841
      flesch: 47
     summary: Bed occupancy was derived from the Business Intelligence Unit of the Hospital and community incidence was derived from national population data (10) and Department of Health reports of COVID-19 cases (1) Statistical methods: Categorical variables were compared using the chi square test or Fisher's exact test. Healthcare associated COVID-19 infections (HA-COVID-19) have been reported in other studies (5) but the literature on epidemiology, risk factors and outcomes of healthcare acquisition of COVID-19 among healthcare inpatients is lacking.
    keywords: cases; covid-19; incidence; license; medrxiv; patients; preprint; rna; staff
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        item: #6440 of 7819
          id: cord-338683-nzgnpi6f
      author: Karligkiotis, Apostolos
       title: Changing paradigms in sinus and skull base surgery as the COVID‐19 pandemic evolves: Preliminary experience from a single Italian tertiary care center
        date: 2020-06-08
       words: 4310
      flesch: 37
     summary: However, after March 23, 2020, indications for PPE use changed and, since then, surgical procedures in COVID-19 negative patients required the use of the highest individual protection standards (at least FFP2 masks), in consideration of the significant number of false negatives resulting from the swab tests currently used. Table 4 provides a summary of the survey conducted, highlighting data regarding exposition to COVID-19 positive patients, the use of PPE and the diagnostic tests performed.
    keywords: base; care; covid-19; health; pandemic; patients; period; skull; surgery
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        item: #6441 of 7819
          id: cord-338684-po3hfibp
      author: Cheong, Kai Xiong
       title: Systematic Review of Ocular Involvement of SARS-CoV-2 in Coronavirus Disease 2019
        date: 2020-09-26
       words: 5036
      flesch: 55
     summary: In contrast, other studies have reported the detection of SARS-CoV-2 in ocular samples from patients who did not experience ocular symptoms and signs Studies have reported ocular involvement in the coronavirus disease 2019 (COVID-19), with SARS-CoV-2 having been detected in ocular swab samples.
    keywords: conjunctival; cov-2; covid-19; patients; samples; sars; signs; symptoms
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        item: #6442 of 7819
          id: cord-338689-4u1ezk64
      author: Ata, Fateen
       title: COVID-19 presenting with diarrhoea and hyponatraemia
        date: 2020-06-07
       words: 1409
      flesch: 48
     summary: 4 Gastrointestinal symptoms such as diarrhoea, abdominal pain and vomiting have been previously seen with acute viral respiratory infections and reported recently as rare manifestations of COVID-19. Our patient had acute hyponatraemia, abdominal pain and diarrhoea with minimal Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study The species severe acute respiratory syndromerelated coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 WHO Director-General's opening remarks at the media briefing on COVID-19 -11 Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Clinical and virological factors associated with gastrointestinal symptoms in patients with acute respiratory infection: a two-year prospective study in general practice medicine Clinical features of patients infected with 2019 novel coronavirus in Wuhan A novel coronavirus associated with severe acute respiratory syndrome COVID-19: gastrointestinal manifestations and potential fecaloral transmission Legionnaires' disease Hyponatraemia and the inappropriate ADH syndrome in pneumonia COVID-19 pathophysiology: a review T cell-mediated immune response to respiratory coronaviruses Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes The International Bank for Reconstruction and Development / The World Bank Competing interests None declared.
    keywords: covid-19; disease; pain; patient
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        item: #6443 of 7819
          id: cord-338706-566e3o5j
      author: Popa, Simona
       title: Reflections on COVID-19 and the future of education and learning
        date: 2020-09-29
       words: 2651
      flesch: 51
     summary: For education communities, this is a chance to take a close look at aspects of education systems that we have taken for granted for far too long. The economic and social effects of lockdowns, loss of production and business confidence, and global recession will cast a long shadow over education systems (Keith Lewin, in this special issue).
    keywords: covid-19; crisis; education; future; learning; pandemic
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        item: #6444 of 7819
          id: cord-338729-v2suoj3c
      author: Streicher, Caroline
       title: Could Tocilizumab be an Attractive Therapeutic Option for Elderly Patients with Severe COVID-19? A Case Report
        date: 2020-09-20
       words: 1639
      flesch: 43
     summary: Recently, there have been an increased number of studies on the use of tocilizumab treatment for severe COVID-19 patients, but more information is needed on its effectiveness and safety, notably for the treatment of elderly patients. To date, no therapy has been approved for the treatment of COVID-19, but targeting IL-6 with tocilizumab treatment could be a potential therapeutic option for patients with COVID-19-induced CRS
    keywords: covid-19; day; patients; tocilizumab; treatment
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        item: #6445 of 7819
          id: cord-338741-gy3ovkrt
      author: Sethi, Atin
       title: Evaluation of Current Therapies for COVID-19 Treatment
        date: 2020-07-22
       words: 5592
      flesch: 44
     summary: The authors suggested that physicians should test for SARS-CoV-2 antibodies in hospitalized patients before treatment with convalescent plasma. In patients with mechanical ventilation, dexamethasone reduced mortality by 1/3, and by 1/5 in those receiving oxygen alone.
    keywords: control; cov-2; covid-19; efficacy; hydroxychloroquine; patients; sars; study; treatment; trial; use
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        item: #6446 of 7819
          id: cord-338754-xdid58vn
      author: Olisova, O. Yu
       title: Cutaneous manifestations in COVID‐19: a skin rash in a child
        date: 2020-05-30
       words: 575
      flesch: 55
     summary: Our observation confirms the idea that the COVID-19 infectious syndrome not infrequent l y includes different types of skin rashes and as seen in this first description with a rare involveme nt of the oral mucous membranes. key: cord-338754-xdid58vn authors: Olisova, O. Yu; Anpilogova, E.M.; Shnakhova, L.M. title: Cutaneous manifestations in COVID‐19: a skin rash in a child date: 2020-05-30 journal: Dermatol Ther DOI: 10.1111/dth.13712 sha: doc_id: 338754 cord_uid: xdid58vn nan symptoms in children are fever, dry cough, fatigue, sometimes respiratory or gastrointestina l symptoms 3 .
    keywords: covid-19; skin
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        item: #6447 of 7819
          id: cord-338756-jzz250o1
      author: Zhang, Nan
       title: Epidemiologic and clinical characteristics of 42 deaths caused by SARS-CoV-2 infection in Wuhan, China: A retrospective study
        date: 2020-07-15
       words: 1647
      flesch: 49
     summary: Impaired consciousness level, markers of renal impairment and coagulation abnormalities may be poor prognostic factors A Novel Coronavirus from Patients with Pneumonia in China A novel coronavirus outbreak of global health concern Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China A pneumonia outbreak associated with a new coronavirus of probable bat origin Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia The data suggested that disseminated intravascular coagulation (DIC) was associated with the outcomes of death, in patients with COVID-19 infection.
    keywords: covid-19; infection; patients; risk
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        item: #6448 of 7819
          id: cord-338757-fsid4a39
      author: Bibbins-Domingo, Kirsten
       title: This Time Must Be Different: Disparities During the COVID-19 Pandemic
        date: 2020-04-28
       words: 1448
      flesch: 37
     summary: We need robust data to guide these efforts, but better information must be coupled with urgent and effective action to decrease exposure, susceptibility, and limitations in health care to achieve the desired results. Establishing and nurturing trust and partnerships within affected communities will be critical because diminished trust in health care borne from a legacy of unethical experimentation, including the Tuskegee study, has been identified as an important contributor to vaccine hesitancy among African Americans (8, 9) .
    keywords: communities; covid-19; disparities; health; minority
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        item: #6449 of 7819
          id: cord-338790-rvdoq616
      author: Wang, Xiaowen
       title: Be aware of acute kidney injury in critically ill children with COVID-19
        date: 2020-08-26
       words: 2909
      flesch: 41
     summary: A delineation of complement activation in COVID-19 will also shed light on the use of complement inhibitory therapy in COVID-19 patients with AKI. We investigated incidence and treatment of AKI in pediatric patients with COVID-19 in Wuhan Children’s Hospital during the early stages of the COVID-19 pandemic and discuss possible mechanisms of AKI related to SARS-CoV-2 infection.
    keywords: acute; aki; children; covid-19; injury; kidney; patients; sars
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        item: #6450 of 7819
          id: cord-338795-eewr8ynb
      author: Oster, Alexandra M.
       title: Transmission Dynamics by Age Group in COVID-19 Hotspot Counties — United States, April–September 2020
        date: 2020-10-16
       words: 1196
      flesch: 41
     summary: ¶ These findings corroborate regional patterns in the southern United States, where increased percent positivity among adults aged 20-39 years preceded increases among those aged ≥60 years (2); provide evidence that among young adults, those aged 18-24 years demonstrate the earliest increases in percent positivity; and underscore the importance of reducing transmission from younger populations § https://www2.census.gov/geo/pdfs/maps-data/maps/reference/us_regdiv.pdf. Percent positivity among persons aged 18-24 years was near its peak of 15% by the date of hotspot detection; however, among other age groups, percent positivity continued to increase for 21-33 days after hotspot detection, peaking at 10%-14%, and the decline for other age groups was slower than that for persons aged 18-24 years.
    keywords: hotspot; percent; positivity
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        item: #6451 of 7819
          id: cord-338814-r9ym1h3m
      author: Li, Yan
       title: Using social media for telemedicine during the COVID-19 epidemic
        date: 2020-08-17
       words: 541
      flesch: 52
     summary: key: cord-338814-r9ym1h3m authors: Li, Yan; Zhang, Kai title: Using social media for telemedicine during the COVID-19 epidemic date: 2020-08-17 journal: Am J Emerg Med DOI: 10.1016/j.ajem.2020.08.007 sha: doc_id: 338814 cord_uid: r9ym1h3m nan measures to prevent the spread of the epidemic [1] [2] [3] . Social media played an essential role during the COVID-19 epidemic.
    keywords: covid-19; media
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        item: #6452 of 7819
          id: cord-338819-wkb318sq
      author: Saez, Marc
       title: Effects of long-term exposure to air pollutants on the spatial spread of COVID-19 in Catalonia, Spain
        date: 2020-09-12
       words: 9831
      flesch: 49
     summary: These reports declare positive cases as well as suspicious ones. where ߠ ௧ , is the mathematical expectation of ܻ ௧ , ‫ܧ‬ሺܻ ௧ ሻ = ߠ ௧ ; ݅ = 1, … , ݊; ‫,…,2,1=ݐ‬ 82; where t = 1 corresponded to February 25 and t = 82 to May 16, 2020; and ‫݊݅ݐ݈ܽݑܲ‬ was the population at risk of being a case (positive case or death) in the small area ݅ and on day ‫.ݐ‬ The link functions of the GLMMs were as follows:
    keywords: air; area; cases; covid-19; deaths; et al; exposure; number; pollutants; population; risk; variables
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        item: #6453 of 7819
          id: cord-338821-khc3dqay
      author: Zhang, Kai
       title: Treatment concerns for psychiatric symptoms in patients with COVID-19 with or without psychiatric disorders
        date: 2020-04-09
       words: 504
      flesch: 37
     summary: If a patient with psychiatric disorder is infected with COVID-19, antiviral drugs must be used in combination with psychotropic drugs, including antipsychotic, antidepressant and antianxiety drugs. First, many patients with psychiatric disorders have been infected with COVID-19, and second, patients with COVID-19 infections may develop a number of psychiatric symptoms, including anxiety, fear, depression and insomnia, after treatment with antiviral drugs.
    keywords: covid-19; drugs
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        item: #6454 of 7819
          id: cord-338830-h2nrw374
      author: Gong, Xiaohuan
       title: Three infection clusters related with potential pre-symptomatic transmission of coronavirus disease (COVID-19), Shanghai, China, January to February 2020
        date: 2020-08-20
       words: 4597
      flesch: 48
     summary: Following Case 1E's detection as suspected COVID-19 case on 29 January, Case 1A returned to hospital alone and was suspected as COVID-19 case one day later, when they were isolated and treated. Investigators interviewed COVID-19 cases, close contacts and healthcare workers directly (face-to-face or over the phone) to collect epidemiological information including demographic characteristics, date of illness onset, hospital visits, close contacts, activities' trajectories between 14 days before illness onset and isolation and exposure histories (i.e. travel to or living in Wuhan or Hubei Province, visiting any other area with local sustained transmission of SARS-CoV-2, contact with persons with respiratory symptoms, contact with suspected or confirmed COVID-19 cases).
    keywords: case; covid-19; hospital; illness; january; onset; shanghai; transmission
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        item: #6455 of 7819
          id: cord-338857-9zbtngje
      author: Tee, Louis Yunshou
       title: Atypical Presentation of COVID‐19 in an Older Adult: Lethargy and Vomiting from Severe Hypovolemic Hyponatremia
        date: 2020-07-08
       words: 999
      flesch: 48
     summary: For instance, COVID-19 can manifest in older patients as delirium or falls, without fever or respiratory symptoms 6, 7 . 75% of known COVID-19 cases are aged over 50, and the case fatality rate ranges from 8% to 15% in patients aged above 70 4, 5 .
    keywords: covid-19; patient
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        item: #6456 of 7819
          id: cord-338863-0jlp9lb4
      author: Huecker, Martin
       title: COVID-19: Optimizing healthcare provider wellness and posttraumatic growth
        date: 2020-08-27
       words: 1251
      flesch: 31
     summary: After SARS 2003, respondents in Hong Kong reported increased care for family, more focus on mental health, and more time devoted to relaxation (17) . medRxiv Vicarious traumatization in the general public, members, and non-members of medical teams aiding in COVID-19 control A comparison of burnout frequency among oncology physicians and nurses working on the front lines and usual wards during the COVID-19 epidemic in Wuhan Psychological resilience and post-traumatic growth in disaster-exposed organisations: overview of the literature Positive mental health-related impacts of the SARS epidemic on the general public in Hong Kong and their associations with other negative impacts Preserving mental health and resilience in frontline healthcare workers during COVID-19.
    keywords: covid-19; growth; health; healthcare
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        item: #6457 of 7819
          id: cord-338864-yzcvxwpb
      author: Dragovic, Milan
       title: Emergency department mental health presentations before and during the COVID-19 outbreak in Western Australia
        date: 2020-09-22
       words: 1615
      flesch: 42
     summary: This study aimed to examine whether emergency departments (EDs) also recorded a rise in mental health presentations. METHOD: Changes in the number, and type, of mental health presentations to Western Australia EDs were examined between January and May 2020, and compared to 2019.
    keywords: covid-19; health; presentations; service
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        item: #6458 of 7819
          id: cord-338889-7hd3iibk
      author: Solbakk, Jan Helge
       title: Back to WHAT? The role of research ethics in pandemic times
        date: 2020-11-03
       words: 11708
      flesch: 47
     summary: In this paper we disentangle some of the arguments put forward in the ongoing debate about Covid-19 human challenge studies (CHIs) and the concomitant role of health-related research ethics in pandemic times. In the next paragraph of this paper we will examine and critique in detail four position statements advocating the epistemological and ethical justifiability of conducting Covid-19 CHI-studies: P. Singer and R.Y. Chappell's, Pandemic ethics: The case for experiments on human volunteers 12 ; the report, Key criteria for the ethical acceptability of COVID-19 human challenge studies, issued by a working group set up by WHO 13 ; the Policy Forum statement, Ethics of controlled human infection to study by Shah, Miller, Darton et al.; 14 and Jamrozik and Selgelid's statement, In addition, we will consider other recent papers advocating the use of Covid-19 CHIs studies.
    keywords: challenge; cov-2; covid-19; et al; ethical; ethics; human; infection; pandemic; participants; research; rights; risk; sars; studies; study; trial; uncertainty; vaccine; virus
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        item: #6459 of 7819
          id: cord-338895-c2wzjbgb
      author: Machado, J. A. Tenreiro
       title: Rare and extreme events: the case of COVID-19 pandemic
        date: 2020-05-16
       words: 5458
      flesch: 53
     summary: The paper addresses the statistical comparison and visualization of COVID-19 country reported cases in the period December 31, 2019, up to April 12, 2020. We adopt the Canberra distance to measure the dissimilarity between pairs (i, j) for the time and frequency domains: Real data Fitting model that is, distances based on the variables y i (t) = t n=1 x i (n) and X i (ıω), respectively, where Re{·} and Im{·} denote the real and imaginary parts.
    keywords: countries; covid-19; data; mds; models; number; time
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        item: #6460 of 7819
          id: cord-338896-relelmsm
      author: Naudin, Iris
       title: Acute aorto-iliac occlusion in patient with COVID-19.
        date: 2020-10-17
       words: 779
      flesch: 41
     summary: key: cord-338896-relelmsm authors: Naudin, Iris; Long, Anne; Michel, Christophe; Devigne, Bertrand; Millon, Antoine; Della-Schiava, Nellie title: Acute aorto-iliac occlusion in patient with COVID-19. It may be useful to know the level of AT in patients with COVID-19 with acute arterial 4 occlusion in order to manage anticoagulation treatment.
    keywords: covid-19; iliac; patient
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        item: #6461 of 7819
          id: cord-338900-8ojah695
      author: MacDonald, David S. MacDonald
       title: Guidelines for Oral and Maxillofacial Imaging: COVID-19 Considerations
        date: 2020-10-26
       words: 5711
      flesch: 37
     summary: COVID-19 Considerations date: 2020-10-26 journal: Oral Surg Oral Med Oral Pathol Oral Radiol DOI: 10.1016/j.oooo.2020.10.017 sha: doc_id: 338900 cord_uid: 8ojah695 SARS-CoV-2, the virus causing the current COVID-19 pandemic, is not only highly infectious but can induce serious outcomes in vulnerable individuals including dental patients and dental health care providers (DHCP). A meta-analysis The emerging role of maxillofacial radiology in the diagnosis and management of patients with complex periodontitis Accuracy of extraoral bite-wing radiography in detecting proximal caries and crestal bone loss The choice of gold standard for evaluating tests for caries diagnosis Intraoral versus extraoral bitewing radiography in detection of enamel proximal caries: an ex vivo study Ex vivo evaluation of new 2D and 3D dental radiographic technology for detecting caries Patient risk related to common dental radiographic examinations: the impact of 2007 International Commission on Radiological Protection recommendations regarding dose calculation Effective dose of dental CBCT -a meta analysis of published data and additional data for 9 CBCT units Clinical decision making and importance of AAOMR/AAE position statement for CBCT examination in endodontic cases Validity of micro-CT for in vitro caries detection: a systematic review and metaanalysis The effects of orthodontic materials on the accuracy of periapical radiography-based caries detection Diagnostic accuracy of different display types in detection of recurrent caries under restorations by using CBCT Precision of cone beam CT to assess periodontal bone defects: a systematic review and meta-analysis Periodontal disease Accuracy and usefulness of CBCT in periodontology: A systematic review of the literature Ex vivo comparison of CBCT and digital periapical radiographs for the quantitative assessment of periodontal defects Impact of CBCT on treatment decision related to surgical removal of impacted maxillary third molars: does CBCT change the surgical approach? Cone-beam computed tomography (CBCT) in the UBC Graduate Orthodontic Program International/American/Canadian Association of Dental Research.
    keywords: air; caries; cbct; control; covid-19; dental; disease; dpr; intraoral; pandemic; patients; radiography; use
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        item: #6462 of 7819
          id: cord-338901-1kzy7rts
      author: Li, Heng
       title: Overview of therapeutic drug research for COVID-19 in China
        date: 2020-06-17
       words: 5106
      flesch: 44
     summary: Molecular basis of ribavirin resistance Comparative effectiveness of aerosolized versus oral ribavirin for the treatment of respiratory syncytial virus infections: a single-center retrospective cohort study and review of the literature Ideal oral combinations to eradicate HCV: the role of ribavirin A major outbreak of severe acute respiratory syndrome in Hong Kong Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area Short term outcome and risk factors for adverse clinical outcomes in adults with severe acute respiratory syndrome (SARS) Severe acute respiratory syndrome: report of treatment and outcome after a major outbreak Ribavirin and interferonbeta synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study Use of chloroquine in viral diseases Effects of chloroquine on viral infections: an old drug against today's diseases? Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Evidence for a common evolutionary origin of coronavirus spike protein receptor-binding subunits Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Progress in antiviral therapy of new coronavirus pneumonia Arbidol as a broad-spectrum antiviral: an update Arbidol: a broad-spectrum antiviral compound that blocks viral fusion The synthetic antiviral drug arbidol inhibits globally prevalent pathogenic viruses Comparison of inhibitory effects of arbidol and Lianhuaqingwen Capsules on Middle East respiratory syndrome coronavirus in vitro and in vivo Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment Dancing with chemical formulae of antivirals: a personal account Dancing with chemical formulae of antivirals: A panoramic view (Part 2) Mechanism of action of T-705 against influenza virus. In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds Combined adjuvant effect of ginseng stem-leaf saponins and selenium on immune responses to a live bivalent vaccine of Newcastle disease virus and infectious bronchitis virus in chickens Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor Structural basis of receptor recognition by SARS-CoV-2 Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds Learning from the past: possible urgent prevention and treatment options for severe acute respiratory infections caused by 2019-nCoV Nucleotide analogues as inhibitors of viral polymerases SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor
    keywords: antiviral; chinese; clinical; coronavirus; cov-2; covid-19; medicine; pneumonia; rna; sars; treatment
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        item: #6463 of 7819
          id: cord-338904-kavbrg1h
      author: Tian, Jianbo
       title: Challenges and recommendations for cancer care in the COVID-19 pandemic
        date: 2020-08-15
       words: 1749
      flesch: 43
     summary: Global cancer statistics 2018: globocan estimates of incidence and mortality worldwide for 36 cancers in 185 countries Cancer patients in SARS-COV-2 infection: a nationwide analysis in China Patients with cancer appear more vulnerable to SARS-COV-2: a multicenter study during the COVID-19 outbreak Clinical characteristics and risk factors associated with COVID-19 disease severity in patients with cancer in Wuhan, China: a multicentre, retrospective, cohort study Clinical characteristics, outcomes, and risk factors for mortality in patients with cancer and COVID-19 in Hubei, China: a multicentre, retrospective, cohort study Case fatality rate of cancer patients with COVID-19 in a New York hospital system Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan SARS-COV-2 transmission in patients with cancer at a tertiary care hospital in Wuhan, China Safeguarding cancer care in a post-COVID-19 world Cancer guidelines during the COVID-19 pandemic A war on two fronts: cancer care in the time of COVID-19 Provision of cancer care during the COVID-19 pandemic Active and effective measures for the care of patients with cancer during the COVID-19 spread in China Challenges and recommendations for cancer care in the COVID-19 pandemic This work was supported by the National Science Fund for Distinguished Young Researchers of China (Grant No. NSFC-81925032). Lee and colleagues 9 have concluded that if effective cancer treatments are withheld from many cancer patients during the pandemic, there will be a very real risk of increasing cancer morbidity and mortality, to levels perhaps much greater than those due to COVID-19 itself.
    keywords: cancer; care; covid-19; patients
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        item: #6464 of 7819
          id: cord-338928-y5l7cf31
      author: Leonardi, Matilde
       title: Neurological manifestations associated with COVID-19: a review and a call for action
        date: 2020-05-20
       words: 2113
      flesch: 30
     summary: Reports from China describe neurological symptoms in COVID-19 patients with one retrospective case series from Wuhan, China showing 78 of 214 patients (36%) with neurological manifestations Respiratory distress is the most distinctive symptom (55%) reported in COVID-19 patients [7] .
    keywords: coronavirus; covid-19; manifestations; patients; sars; symptoms
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        item: #6465 of 7819
          id: cord-338933-67e98ok3
      author: Howarth, Candice
       title: Building a Social Mandate for Climate Action: Lessons from COVID-19
        date: 2020-07-08
       words: 4041
      flesch: 46
     summary: This commentary draws lessons from the COVID-19 crisis for climate change. There has been no shortage of commentary on what we can learn from the COVID-19 pandemic for climate change.
    keywords: action; change; citizens; climate; covid-19; response
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        item: #6466 of 7819
          id: cord-338934-61wnbf1t
      author: Fay, Daniel L.
       title: Collective Bargaining During Times of Crisis: Recommendations from the COVID‐19 Pandemic
        date: 2020-05-19
       words: 4121
      flesch: 34
     summary: State policy can dramatically influence union membership, mobilization efforts, and civic participation of members, but public employee unions also influence policy making at every level of government, and union commitment can directly and indirectly increase employee job satisfaction (Davis, 2013; Flavin & Hartney, 2015; Riccucci, 2011) . Public employee unions should be mindful of the interconnectedness of public policy and public labor relations during impact bargaining and integrate the government response to the crisis and negotiations.
    keywords: bargaining; covid-19; crisis; employees; impact; labor; members; negotiations; public; union
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        item: #6467 of 7819
          id: cord-338944-3ro3evcc
      author: Cho, Dae-Chul
       title: In the Era of COVID-19: The Role of Spine Surgeons at the Epicenter of the Outbreak
        date: 2020-05-18
       words: 470
      flesch: 42
     summary: When operating on COVID-19 infected patients, all efforts are made to minimize exposure to the patient by maintaining as much of a distance as possible, as well as by minimizing medical staff in the OR during the surgery to increase the safety of the operation. However, during this crisis, spine surgeons must pay attention not only to our traditional mission in the field of spine surgery, but also to new additional objectives as part of our dedicated efforts to fight against virus.
    keywords: covid-19; patients
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        item: #6468 of 7819
          id: cord-338951-wu1ofih9
      author: Sestili, Piero
       title: Paracetamol-Induced Glutathione Consumption: Is There a Link With Severe COVID-19 Illness?
        date: 2020-10-07
       words: 4667
      flesch: 25
     summary: In March 2020, ibuprofen and NSAIDs were discouraged because of the alert by Micallef et al. on the supposed aggravation of COVID-19 (Micallef et al., 2020a; Micallef et al., 2020b) . This warning was grounded on a wide number of studies reviewed in (Micallef et al., 2020b) including a recent report of the French Pharmacovigilance Network conducted in 2019 (Crpv De Tours, CRPV de Marseille, 2019) showing that the use of NSAIDs (even if given for short times and/or associated to antibiotics) for the treatment of fever and nonrheumatic pain (which may be indicative of an underlying infection) increases the risk of severe bacterial complications, particularly of the lungs, and on the supposed ibuprofen-induced A angiotensin-converting enzyme 2 (ACE2) overexpression.
    keywords: covid-19; et al; glutathione; gsh; levels; nsaids; pac; paracetamol; patients; risk; use
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        item: #6469 of 7819
          id: cord-338968-b1gg2ha7
      author: La Rosée, Felicitas
       title: Ruxolitinib in COVID-19 Hyperinflammation and Haematologic Malignancies
        date: 2020-08-20
       words: 1091
      flesch: 29
     summary: Rojas and Sarmiento and a few other authors of anecdotic reports on patients with malignancies and COV-ID-19 provide meaningful insight on patients, who hardly entered clinical trials on COVID-19 protocols due to their malignant comorbidity [3] [4] [5] [6] In this issue of Acta Haematologica, Rojas and Sarmiento [4] from Chile report on 3 patients with progressive COVID-19 successfully treated with rux 10 mg b.i.d., thereby adding anecdotal evidence to the list of positive reports on rux in COVID-19 patients with moderate or severe disease.
    keywords: covid-19; dex; patients; treatment
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        item: #6470 of 7819
          id: cord-338972-uq2ha8xs
      author: Olson, Michael T.
       title: Resumption of elective surgery during the COVID-19 pandemic: what lessons can we apply?
        date: 2020-06-05
       words: 1689
      flesch: 27
     summary: key: cord-338972-uq2ha8xs authors: Olson, Michael T.; Triantafyllou, Tania; Singhal, Saurabh title: Resumption of elective surgery during the COVID-19 pandemic: what lessons can we apply? date: 2020-06-05 journal: Eur Surg DOI: 10.1007/s10353-020-00645-0 sha: doc_id: 338972 cord_uid: uq2ha8xs nan it appropriate to return to a normal-capacity surgical practice? The goal to optimally provide safe and high-quality surgical care has not wavered, but in resuming elective surgery, it remains vitally important to be considerate of its risks.
    keywords: covid-19; pandemic; patients; sars; surgery
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        item: #6471 of 7819
          id: cord-338973-73a7uvyz
      author: Xu, Jiabao
       title: Systematic Comparison of Two Animal-to-Human Transmitted Human Coronaviruses: SARS-CoV-2 and SARS-CoV
        date: 2020-02-22
       words: 7127
      flesch: 54
     summary: Nelfinavir was predicted to be a potential inhibitor of 2019 nCov main protease by an integrative approach combining homology modelling, molecular docking and binding free energy calculation Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV A randomized, controlled trial of Ebola virus disease therapeutics First Case of 2019 Novel Coronavirus in the United States Research progress on novel coronavirus (2019-nCoV) related drugs in vitro/vivo Friendship Hospital: Clinical Experimental Research Work Is Being Carried Out on Remdesivir Recombination in large RNA viruses Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus Genomic characterisation and epidemiology of 2019 novel coronavirus: Implications for virus origins and receptor binding SARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes Jumping species-A mechanism for coronavirus persistence and survival Serological evidence of bat SARS-related coronavirus infection in humans Clinical virology and pathogenesis Expression of elevated levels of pro-inflammatory cytokines in SARS-CoV-infected ACE2+ cells in SARS patients: Relation to the acute lung injury and pathogenesis of SARS Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. Epidemic Update and Risk Assessment of 2019 Novel Coronavirus Return of the Coronavirus: 2019-nCoV. Viruses Clinical manifestations, laboratory findings, and treatment outcomes of SARS patients Middle East respiratory syndrome: Emergence of a pathogenic human coronavirus Diagnosis and Treatment of Pneumonia Caused by 2019-nCoV (Trial Version 4) Pulmonary rehabilitation guidelines in the principle of 4S for patients infected with 2019 novel coronavirus (2019-nCoV) Incubation periods of acute respiratory viral infections: A systematic review Multiple contact dates and SARS incubation periods A novel coronavirus from patients with pneumonia in China A novel coronavirus outbreak of global health concern The severe acute respiratory syndrome The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: An analysis of all 1755 patients Infectious Disease Expert Li Lanjuan Responded to Six Questions of 2019-nCoV Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia Clinical features of patients infected with 2019 novel coronavirus in Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study Press Conference of the National Health Commission of the People's Republic of China on 3 Intraspecies diversity of SARS-like coronaviruses in Rhinolophus sinicus and its implications for the origin of SARS coronaviruses in humans Novel coronavirus: From discovery to clinical diagnostics SARS-CoV infection in a restaurant from palm civet Discovery of a novel coronavirus associated with the recent pneumonia outbreak in humans and its potential bat origin Host and infectivity prediction of Wuhan 2019 novel coronavirus using deep learning algorithm Homologous recombination within the spike glycoprotein of the newly identified coronavirus may boost cross-species transmission from snake to human Pangolin May Be a Potential Intermediate Host of New Coronavirus.
    keywords: cases; china; coronavirus; cov; cov-2; covid-19; disease; human; mers; patients; pneumonia; protein; sars; severe
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        item: #6472 of 7819
          id: cord-338979-ew046wcr
      author: Jasti, Madhu
       title: A review of pathophysiology and neuropsychiatric manifestations of COVID-19
        date: 2020-06-03
       words: 2979
      flesch: 39
     summary: Presenting as acute ST elevation myocardial infarction Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China Smell dysfunction: a biomarker for COVID-19 Evidence of the COVID-19 virus targeting the CNS: tissue distribution, hostvirus interaction, and proposed neurotropic mechanisms High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients National Health Commission of the People′s Republic of China. Losses of smell and taste have been strongly linked to COVID-19 infections [12] .
    keywords: acute; brain; coronavirus; covid-19; disease; patients; sars; system
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        item: #6473 of 7819
          id: cord-338990-vrtzyo2o
      author: Nelson, Sarah E.
       title: COVID-19 and ethics in the ICU
        date: 2020-08-25
       words: 1229
      flesch: 43
     summary: Based on these principles, 6 recommendations have been made for the current outbreak: maximizing benefits including using scarce resources responsibly and saving more lives/years of life, prioritizing COVID-19 resources (i.e., PPE, vaccines) to healthcare workers, invoking equality using random allocation or lottery to distribute resources to those with similar prognoses, thoughtful consideration of resource allocation (e.g., prioritizing older patients, among the most affected by SARS-CoV-2, to receive a vaccine), prioritizing those who have participated in COVID-19-related research, and providing equal resources to those with COVID-19 and those with other medical conditions [9] . The hippocratic oath today COVID-19: protecting health-care workers Memoriam: Healthcare workers who have died of COVID-19 Physicians are disposable and are taken for granted Facing Covid-19 in Italy -ethics, logistics, and therapeutics on the epidemic's front line Scarce resource allocation during disasters: a mixed-method community engagement study Too many patients … a framework to guide statewide allocation of scarce mechanical ventilation during disasters Fair allocation of scarce medical resources in the time of Covid-19 The toughest triage -allocating ventilators in a pandemic Considerations for ventilator triage during the COVID-19 pandemic The psychological trauma that awaits our doctors and nurses Not dying alone -modern compassionate care in the Covid-19 pandemic I'm on the front lines.
    keywords: care; covid-19; resources
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        item: #6474 of 7819
          id: cord-339044-qy4jab37
      author: Li, Man
       title: Analysis of the Risk Factors for Mortality in Adult COVID-19 Patients in Wuhan: A Multicenter Study
        date: 2020-08-25
       words: 2593
      flesch: 46
     summary: In addition to age factors, we also found D-dimer levels >1,000 ng/L, and platelet counts < 125 × 10 9 /L on admission were associated with fatal outcomes in COVID-19 patients. (21) have reported that while COVID-19 patients with significantly elevated platelet count during treatment were on an average hospitalized longer, the platelet count at admission was lower in severely ill patients (169.67 ± 48.95) compared to those who were not severely ill (192.26 ± 58.12).
    keywords: covid-19; disease; factors; patients; risk; study; wuhan
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        item: #6475 of 7819
          id: cord-339075-32jj4fyz
      author: Majeed, Azeem
       title: The primary care response to COVID-19 in England's National Health Service
        date: 2020-06-17
       words: 1900
      flesch: 48
     summary: This led to the Department of Health and Social Care and NHS England (the bodies that respectively fund and manage the NHS in England) to recommend radical changes to the provision of NHS primary care services. Other changes were helped by the existing information technology infrastructure in NHS primary care.
    keywords: care; covid-19; nhs; patients; primary
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        item: #6476 of 7819
          id: cord-339100-600am3mq
      author: Hsiang, Walter R
       title: Scarce COVID-19 Testing Capabilities at Urgent Care Centers in States with Greatest Disease Burden
        date: 2020-03-27
       words: 652
      flesch: 51
     summary: As of March 22, 2020, the number of confirmed COVID-19 cases in the U.S. has reached nearly 30,000. 1 While rapid and accessible diagnosis is paramount to monitoring and reducing the spread of disease, COVID-19 testing capabilities across the U.S. remain constrained. While rapid and accessible diagnosis is paramount to monitoring and reducing the spread of disease, COVID-19 testing capabilities across the U.S. remain constrained.
    keywords: covid-19; uccs
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        item: #6477 of 7819
          id: cord-339111-d6ll48nv
      author: Patterson, Joanne M
       title: COVID‐19 and ENT SLT services, workforce and research in the UK: A discussion paper
        date: 2020-08-08
       words: 6633
      flesch: 38
     summary: The COVID‐19 pandemic has created both opportunities and threats for ENT SLT clinical services, workforce and research. A summary of the main threats and opportunities for ENT SLT clinical services is provided in table 1.
    keywords: airway; care; covid-19; ent; health; pandemic; patients; practice; research; services; slt; slts; treatment; voice; workforce
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        item: #6478 of 7819
          id: cord-339121-w16e8lw1
      author: Ebuenyi, Ikenna D
       title: COVID-19 as social disability: the opportunity of social empathy for empowerment
        date: 2020-08-23
       words: 1706
      flesch: 36
     summary: key: cord-339121-w16e8lw1 authors: Ebuenyi, Ikenna D; Smith, Emma M; Holloway, Catherine; Jensen, Rune; D'Arino, Lucía; MacLachlan, Malcolm title: COVID-19 as social disability: the opportunity of social empathy for empowerment date: 2020-08-23 journal: BMJ Glob Health DOI: 10.1136/bmjgh-2020-003039 sha: doc_id: 339121 cord_uid: w16e8lw1 nan Social empathy is 'the ability to more deeply understand people by perceiving or experiencing their life situations and as a result gain insight into structural inequalities and disparities'. These few examples provide the general population an opportunity for social empathy and action to enhance social inclusion for people with disability.
    keywords: covid-19; disability; experience; persons
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        item: #6479 of 7819
          id: cord-339124-m7choyr6
      author: Hoang, Van-Thuan
       title: Hajj and Umrah Mass Gatherings and COVID-19 Infection
        date: 2020-11-03
       words: 4384
      flesch: 47
     summary: Duration of event ✓ Keeping the duration of the event to a minimum to limit contact among participants • Risk communication ✓ Ensuring coordination and consistency in crafting and delivering culturally appropriate and language specific messages to participants and the public ✓ Disseminating key messages in line with national health policies • Surveillance of participants, aimed at detecting and managing individuals developing symptoms during the event ✓ Detection and management of event-related COVID-19 cases should be conducted in accordance with national policies and regulations, within the framework of national health systems ✓ Isolation facilities should be made available at the event site ✓ Arrangements with national and local health authorities regarding diagnosis and treatment of COVID-19 cases identified during the event Post-event phase Liaison between event organizers and health authorities, along the following lines: ✓ In case participants or staff develop symptoms during the event, event organizers should liaise with national and local health authorities, as well with those of the participant's home city or country, and facilitate sharing of information ✓ Individuals who develop symptoms upon returning to their home city or country should be advised to contact public health authorities about their potential exposure ✓ Liaison between event organizers and health authorities is required to ensure that systems are in place to detect cases arising The level of COVID-19 outbreak had been linked to large religious MGs in several countries. Hajj statistics 2019-1440 Forecasting the spread of the COVID-19 pandemic in Saudi Arabia using ARIMA prediction model under current public health interventions Global perspectives for prevention of infectious diseases associated with mass gatherings Non-pharmaceutical interventions for the prevention of respiratory tract infections during Hajj pilgrimage Covid-19 and community mitigation strategies in a pandemic A single mass gathering resulted in massive transmission of COVID-19 infections in Malaysia with further international spread COVID-19 outbreak on the diamond princess cruise ship in The delay in confirming COVID-19 cases linked to a religious Group in Korea Large outbreak of coronavirus disease among wedding attendees Spread of Novel coronavirus by returning pilgrims from Iran to Pakistan A cluster of COVID-19 in pilgrims to Israel Pilgrimage and COVID-19: the risk among returnees from Muslim countries This study funds a high attack rate (38%) of SARS-CoV-2 infection at a mass gathering event Risk factors of critical & mortal COVID-19 cases: a systematic literature review and meta-analysis Who's at higher risk from coronavirus (COVID-19) Antibiotic use for respiratory infections among Hajj pilgrims: a cohort survey and review of the literature An evaluation of health policy implementation for Hajj pilgrims in Indonesia Outbreak dynamics of COVID-19 in Europe and the effect of travel restrictions Observations of the global epidemiology of COVID-19 from the prepandemic period using web-based surveillance: a crosssectional analysis Religious tourism and mass religious gatherings -the potential link in the spread of COVID-19.
    keywords: cases; covid-19; event; hajj; health; pilgrimage; pilgrims; risk; umrah
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        item: #6480 of 7819
          id: cord-339128-npfoircv
      author: Blair, Robert V.
       title: Acute Respiratory Distress in Aged, SARS-CoV-2 Infected African Green Monkeys but not Rhesus Macaques
        date: 2020-11-07
       words: 3101
      flesch: 39
     summary: However, a small subset progress to develop severe respiratory disease which, in some cases, is fatal 1 . Animal models of SARS-CoV-2 infection that manifest severe disease are needed to investigate the pathogenesis of COVID-19 induced ARDS and evaluate therapeutic strategies.
    keywords: agms; animals; ards; covid-19; disease; infection; sars
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        item: #6481 of 7819
          id: cord-339161-ycsijsw4
      author: Friebel, TR
       title: Communication: A Safe Skin Cancer Surgery set-up during the COVID-19 crisis
        date: 2020-11-01
       words: 859
      flesch: 46
     summary: Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services The Effects of a Novel Global Pandemic (COVID-19) on a Plastic Surgery Department Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection COVID-19: the case for health-care worker screening to prevent hospital transmission Clinical guide for the management of essential cancer surgery for adults during the coronavirus pandemic The authors would like to thank the administrative team in admission, especially Fiona Milne and Nicholas Samuels for their help in identifying the patients and screening them before admission. It speaks to the efficiency of PPE and physical distancing that we did not detect any evidence of COVID-19 transmission.
    keywords: covid-19; patients; surgery
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        item: #6482 of 7819
          id: cord-339203-5oextxkm
      author: Feng Tan, L.I.
       title: Preventing the Transmission of COVID-19 Amongst Healthcare Workers
        date: 2020-04-09
       words: 371
      flesch: 47
     summary: However, healthcare workers including non-clinical staff have contracted COVID-19 in the community and from overseas travel 6 . This presents a different challenge to preventing COVID-19 infection in healthcare workers.
    keywords: covid-19
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        item: #6483 of 7819
          id: cord-339252-ph10txit
      author: Keita, Abdoulaye
       title: Anosmie sans agueusie chez des patients COVID-19: à propos de 2 cas
        date: 2020-07-13
       words: 1271
      flesch: 63
     summary: This study highlights that anosmia can occur without aguesia and persist after healing in COVID-19 patients. Medical Hypotheses Non-neural expression of SARS-CoV-2 entry genes in the olfactory epithelium suggests mechanisms underlying anosmia in COVID-19 patients Google Scholar Presentation of new onset anosmia during the COVID-19 pandemic Anosmia as a prominent symptom of COVID-19 infection Self-reported olfactory loss associates with outpatient clinical course in Covid-19
    keywords: covid-19; patients; une
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        item: #6484 of 7819
          id: cord-339266-glmshsh6
      author: Yin, R.
       title: Clinical characteristics of 106 patients with neurological diseases and co-morbid coronavirus disease 2019: a retrospective study
        date: 2020-05-05
       words: 4584
      flesch: 48
     summary: [1] [2] [3] From December 2019 to 15 April 2020, the number of COVID-19 patients worldwide reached 2 million, and the mortality has exceeded 120,000. Novel Coronavirus (2019-nCoV) Situation Report-22 COVID-19: Gastrointestinal manifestations and potential fecal-oral transmission Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients First case of 2019 Novel Coronavirus Disease with Encephalitis A New Symptom of COVID-19:
    keywords: covid-19; diseases; group; license; patients; preprint; study
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        item: #6485 of 7819
          id: cord-339293-7ks3bopm
      author: Nejatifard, Marzieh
       title: Probable Positive Effects of the Photobiomodulation as an Adjunctive Treatment in COVID-19: A Systematic Review
        date: 2020-10-12
       words: 4588
      flesch: 47
     summary: Previous studies have shown the advantages of the PBM including anti-inflammatory effects and acceleration of the wound healing (10) . Keywords included the PBM and related terms, lung inflammation, and COVID-19 -related signs.
    keywords: ards; covid-19; disease; effects; inflammation; laser; lung; papers; patients; pbm
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        item: #6486 of 7819
          id: cord-339300-xherv9wt
      author: Suner, C.
       title: Risk factors for mortality of residents in nursing homes with Covid-19: a retrospective cohort study
        date: 2020-11-10
       words: 4346
      flesch: 40
     summary: Key characteristics of each cluster were as follows: Nursing homes in cluster 1 were placed in low densely populated areas with high population incidence of Covid-19, and high household income; cluster 2 were facilities with a high proportion of CCP and ACD patients, and located in areas with low population incidence of Covid-19; cluster 3 had low proportion of CCPs and highly dependent residents; cluster 4 had higher number of residents than the median, although with a very low proportion of CCPs; nursing homes in this cluster were placed in areas with low household income; cluster 5 had low proportion of ACD patients and dependent residents, and had higher number of residents that returned home with their relatives; cluster 6 were placed in areas with high household income and low population incidence of Covid-19; cluster 7 had high proportion of CCP and ACD patients; nursing homes in this cluster were located in densely populated areas; cluster 8 had a high SNQ12 score-indicating very limited capacity for pandemic preparedness and response-and high proportion of CCPs and older residents than the median. We aimed to explore the contribution of structural factors of nursing home facilities and the surrounding district to all-cause and Covid-19-related deaths during a SARS-CoV-2 outbreak.
    keywords: care; covid-19; deaths; homes; incidence; mortality; nursing; residents; risk
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        item: #6487 of 7819
          id: cord-339336-vea7a1rm
      author: Coates, P. Toby
       title: A Kidney International “Journal of the COVID-19 Year” in Kidney Transplantation
        date: 2020-10-19
       words: 370
      flesch: 25
     summary: A journal of the plague year M An initial report from the French SOT COVID Registry suggests high mortality due to Covid-19 in recipients of kidney transplants COVID-19 infection in kidney transplant recipients Kidney Int Scolari F A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia Kidney Int ZA Results from the ERA-EDTA Registry indicate a high mortality due to COVID-19 in dialysis patients and kidney transplant recipients across Europe IMPact of the COVID-19 epidemic on the moRTAlity of renal transplant recipients and candidates: a French Nationwide registry sTudy (IMPORTANT) COVID-19 Infection in Kidney Transplant Recipients at the Epicenter of pandemics Significant impact of COVID-19 on organ donation and transplantation in a lowprevalence country: Australia key: cord-339336-vea7a1rm authors: Coates, P. Toby title: A Kidney International “Journal of the COVID-19 Year” in Kidney Transplantation date: 2020-10-19 journal: Kidney Int DOI: 10.1016/j.kint.2020.10.006 sha: doc_id: 339336 cord_uid: vea7a1rm nan Population based mortality data provided on 4298 patients from Spain and France were reported to the Registry covering the period from 1 st February 2020 till 30 th April 2020.
    keywords: covid-19; kidney
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        item: #6488 of 7819
          id: cord-339344-qd73h1ie
      author: Simon, David
       title: Patients with immune-mediated inflammatory diseases receiving cytokine inhibitors have low prevalence of SARS-CoV-2 seroconversion
        date: 2020-07-24
       words: 4097
      flesch: 35
     summary: Therapeutic interventions for IMIDs target inflammatory cytokines, such as TNF-α, IL-6, and IL-17 that are both involved in the physiological and pathological host response elicited by SARS-CoV-2 4 . Two recent studies reported that development of a more pronounced anti-SARS-CoV-2 IgG response is linked to more severe disease, suggesting inflammatory responses as important triggers for priming adaptive immunity against SARS-CoV-2 14, 15 .
    keywords: control; cov-2; covid-19; cytokine; igg; imid; infection; inhibitors; patients; risk; sars
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        item: #6489 of 7819
          id: cord-339355-zkkj8a83
      author: Siripanthong, Bhurint
       title: Coronavirus disease 2019 is delaying the diagnosis and management of chest pain, acute coronary syndromes, myocarditis and heart failure
        date: 2020-07-01
       words: 2331
      flesch: 22
     summary: Furthermore, the way in which certain centers approach the diagnosis of ACS or myocardial infarction in COVID-19 patients may have contributed to the decline in the apparent incidence of ischemic heart disease. While there is some rationale to limiting troponin tests to COVID-19 patients with overt cardiac symptoms, especially in the setting of over-burdened clinical resources and the potential for unnecessary staff viral exposure, restricted cardiac enzyme testing could potentially miss true ACS and other cardiac pathology when relatively minor cardiac symptoms are overshadowed by more severe respiratory symptoms.
    keywords: acs; cardiac; covid-19; disease; elevation; infarction; patients
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        item: #6490 of 7819
          id: cord-339360-vm4yy47i
      author: Krywyk, J.
       title: DYNAMICS OF THE COVID-19 PANDEMICS: GLOBAL PATTERN AND BETWEEN COUNTRIES VARIATIONS
        date: 2020-07-26
       words: 3053
      flesch: 53
     summary: This analysis will be updated when more country epidemic cycles are complete, which is not the case for many of the 203 affected countries. A study of epidemic patterns performed by epicenter could also refine previous hypotheses.
    keywords: countries; covid-19; data; epidemic; pattern; preprint; time
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        item: #6491 of 7819
          id: cord-339399-36wo66rl
      author: Trepanier, Sylvain
       title: Leading on the Edge of Insanity
        date: 2020-07-13
       words: 2038
      flesch: 69
     summary: And I am reminded that hope is not a plan; therefore, now is the time to show up as nurse leaders and make a difference. To that end, nurse leaders are encouraged to consider educating all constituents in promoting physical distancing, promoting the use of virtual clinics, eliminating visitations, screening everyone entering a building, cohorting patients, and collaborating with city, military, and state organizations.
    keywords: covid-19; nurse; patients; time
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        item: #6492 of 7819
          id: cord-339400-9uro1xlk
      author: Chang, Yoon-Seok
       title: COVID-19 and allergy
        date: 2020-07-30
       words: 892
      flesch: 44
     summary: Global locations with COVID-19 Ministry of Health and Welfare National Library of Medicine (US) Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan World Allergy Organization; c2020 COVID-19, asthma, and biologic therapies: What we need to know Acute asthma management during SARS-CoV2-pandemic 2020 Importance of microbial extracellular vesicle in the pathogenesis of asthma and chronic obstructive pulmonary disease and its diagnostic potential An epidemic of thunderstorm asthma in Melbourne 2016: asthma, rhinitis, and other previous allergies Natural history of asthma symptoms after epidemic thunderstorm asthma: a 3-year longitudinal study Wheeze sound characteristics are associated with nighttime sleep disturbances in younger children Tolerability to paracetamol and preferential COX-2 inhibitors in patients with cross-reactive nonsteroidal anti-inflammatory drugs hypersensitivity Residents and interns in the 3 university hospitals: their knowledge of and attitudes to drug allergy Utility of an educational video on epinephrine prefilled syringe usage for anaphylaxis: a randomized control trial IgE recognition profile of aeroallergen components in young children sensitized to dogs This issue features a 3-year longitudinal study on the natural history of asthma symptoms after epidemic thunderstorm asthma in Melbourne
    keywords: allergy; asthma; covid-19
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        item: #6493 of 7819
          id: cord-339406-81a7fkpj
      author: Borghi, M. O.
       title: Prevalence, specificity, and clinical association of anti-phospholipid antibodies in COVID-19 patients: are the antibodies really guilty?
        date: 2020-06-19
       words: 3153
      flesch: 51
     summary: Importantly, aPL in COVID-19 patients are mainly reacting against β 2 -glycoprotein I (β 2 GPI) but display an epitope specificity different from antibodies found in APS patients. This data is in line with the unusual epitope specificity of anti-β 2 GPI antibodies documented in Figure 2 , supporting the hypothesis that aPL found in COVID-19 patients are different from aPL found in APS patients.
    keywords: anti; antibodies; apl; covid-19; patients; preprint
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        item: #6494 of 7819
          id: cord-339436-0k73tlna
      author: Giagulli, Vito Angelo
       title: Worse progression of COVID‐19 in men: Is Testosterone a key factor?
        date: 2020-06-11
       words: 7901
      flesch: 32
     summary: [116] These therapeutic aspects emphasized the concept that a blunted antibody response (particularly IgG) may precipitate a severe clinical course in COVID-19 patients. Circulation Endogenous sex hormones and the prospective association with cardiovascular disease and mortality in men: The Tromsø Study Cardiovascular Outcomes and All-cause Mortality Following Measurement of Endogenous Testosterone Levels Low serum testosterone and mortality in older men Fibrinolytic abnormalities in acute respiratory distress syndrome (ARDS) and versatility of thrombolytic drugs to treat COVID-19 Thromboembolic risk and anticoagulant therapy in COVID-19 patients: Emerging evidence and call for action Venous thrombosis and arteriosclerosis obliterans of lower extremities in a very severe patient with 2019 novel coronavirus disease: a case report Effects of age, gender and menstrual cycle on platelet function assessed by impedance aggregometry Platelet activation status decreases after menopause Mean platelet volume in a patient with male hypogonadotropic hypogonadism: The relationship between low testosterone, metabolic syndrome, impaired fasting glucose and cardiovascular risk Endogenous testosterone, fibrinolysis, and coronary heart disease risk in hyperlipidemic men Relationship between sex hormones and haemostatic factors in healthy middle-aged men Coronavirus infections and immune responses SARS-CoV-2 and viral sepsis: observations and hypotheses Focus on Receptors for Coronaviruses with Special Reference to Angiotensin-converting Enzyme 2 as a Potential Drug Target -A Perspective.
    keywords: article; cells; cov-2; covid-19; hypogonadism; immune; levels; male; men; obesity; patients; prognosis; response; risk; sars; serum
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        item: #6495 of 7819
          id: cord-339455-b8nu34vv
      author: Sakr, Yasser
       title: The clinical spectrum of pulmonary thromboembolism in patients with coronavirus disease-2019 (COVID-19) pneumonia: A European case series
        date: 2020-09-25
       words: 2412
      flesch: 34
     summary: The datasets used and analysed during the current report are available from the corresponding author on reasonable request Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Acute Pulmonary Embolism Associated with COVID-19 Pneumonia Detected by Pulmonary CT Angiography Antiphospholipid antibodies are not elevated in patients with severe COVID-19 pneumonia and venous thromboembolism Thrombotic risk in COVID-19: a case series and case-control study Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Diagnosing Pulmonary Thromboembolism in COVID-19: A Stepwise Clinical and Imaging Approach COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up: JACC State-of-the-Art Review Thromboembolic risk and anticoagulant therapy in COVID-19 patients: emerging evidence and call for action SARS-2 Coronavirus-Associated Hemostatic Lung Abnormality in COVID-19: Is It Pulmonary Thrombosis or Pulmonary Embolism? Microthrombotic Complications of COVID-19 Are Likely Due to Embolism of Circulating Endothelial Derived Ultralarge Von Willebrand Factor (eULVWF) Decorated-Platelet Strings Endotheliitis and Endothelial Dysfunction in Patients with COVID-19: Its Role in Thrombosis and Adverse Outcomes High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Incidence of thrombotic complications in critically ill ICU patients with COVID-19 High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Pulmonary Embolism in Patients With COVID-19: Awareness of an Increased Prevalence Thromboembolic events and apparent heparin resistance in patients infected with SARS-CoV-2 Incidence of venous thromboembolism in hospitalized patients with COVID-19 Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19: Report of the National Institute for Public Health of the Netherlands Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases Coagulation disorders in coronavirus infected patients: COVID-19, SARS-CoV-1, MERS-CoV and lessons from the past Systemic endothelial dysfunction: A common pathway for COVID-19, cardiovascular and metabolic diseases COVID-19 and haemostasis: a position paper from Italian Society on Thrombosis and Haemostasis (SISET) Acute Pulmonary Embolism in COVID-19 Patients on CT Angiography and Relationship to D-Dimer Levels Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: A Prospective Cohort Study Pulmonary embolism in patients with COVID-19 pneumonia Thrombotic complications of patients admitted to intensive care with COVID-19 at a teaching hospital in the United Kingdom Enoxaparin 40 mg per Day Is Inadequate for Venous Thromboembolism Prophylaxis After Thoracic Surgical Procedure Efficacy and safety of highdose thromboprophylaxis in morbidly obese inpatients Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia ISTH interim guidance on recognition and management of coagulopathy in COVID-19 Prevention and Treatment of Venous Thromboembolism Associated with Coronavirus Disease 2019
    keywords: associated; covid-19; hospital; patients; pte; therapy; thromboembolism
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        item: #6496 of 7819
          id: cord-339459-z22a5yzo
      author: Mackey, Katherine
       title: Risks and Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers on SARS-CoV-2 Infection in Adults: A Living Systematic Review
        date: 2020-05-15
       words: 4138
      flesch: 36
     summary: JAMA Cardiol Anti-hypertensive angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients Renin-angiotensinaldosterone system blockers and the risk of covid-19 Cardiovascular disease, drug therapy, and mortality in covid-19 Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Covid-19 testing, hospital admission, and intensive care among 2,026,227 United States veterans aged 54-75 years Renin-angiotensinaldosterone system inhibitors and risk of covid-19 Characteristics and outcomes of a cohort of SARS-CoV-2 patients in the province of Reggio Emilia Angiotensin II receptor blockers and angiotensin-converting enzyme inhibitors usage is associated with improved inflammatory status and clinical outcomes in COVID-19 patients with hypertension Hypertension in patients hospitalized with COVID-19 in Wuhan, China: a single-center retrospective observational study Association of inpatient use of angiotensin converting enzyme inhibitors and angiotensin II receptor blockers with mortality among patients with hypertension hospitalized with COVID-19 COVID-19) Observational studies and trials in adults that examined associations and effects of ACEIs or ARBs on risk for SARS-CoV-2 infection and COVID-19 disease severity and mortality.
    keywords: acei; angiotensin; arb; cov-2; covid-19; patients; sars; studies; use
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        item: #6497 of 7819
          id: cord-339460-7hzlyn79
      author: Landsness, Eric C.
       title: Pivoting Research to COVID‐19
        date: 2020-06-07
       words: 1002
      flesch: 33
     summary: Although the panelists find contributing to COVID-19 research efforts fulfilling, unique challenges have emerged. As COVID-19 research enterprises are developed, engaging these under-represented and over-burdened communities will be a high priority.
    keywords: covid-19; patients; research
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        item: #6498 of 7819
          id: cord-339467-ewqxf02j
      author: Liang, Ying
       title: Differential diagnosis of coronavirus disease 2019 from pneumonias caused by other etiologies in a fever clinic in Beijing
        date: 2020-10-20
       words: 1556
      flesch: 48
     summary: Compared with non-COVID-19 patients, a higher proportion of COVID-19 patients had an identified epidemiological history (89.5% vs. 32.8%, P < 0.001). In non-COVID-19 patients, infiltrates on the CT scan mainly involved 1-2 lung lobes, while in COVID-19 patients, lesions involving 4-5 lobes were more common (COVID-19 vs. In this study, we found that epidemiological history was extremely important for identification of suspected cases of COVID-19 and for differential diagnosis.
    keywords: cases; covid-19; non; patients; study
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        item: #6499 of 7819
          id: cord-339491-lyld3up2
      author: Prakash, A.
       title: Using Machine Learning to assess Covid-19 risks
        date: 2020-06-23
       words: 4193
      flesch: 51
     summary: https://doi.org/10.1101/2020.06.23.20137950 doi: medRxiv preprint Generating Multi-label Discrete Patient Records using Generative Adversarial Networks Real-valued (Medical) Time Series Generation with Recurrent Conditional GANs Generating Synthetic but Plausible Healthcare Record Datasets The validity of synthetic clinical data: a validation study of a leading synthetic data generator (Synthea) using clinical quality measures 10,000 Synthetic Medicare Patient Records Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area Association of Public Health Interventions With the Epidemiology of the COVID-19 Outbreak in Wuhan, China Alterations in Smell or Taste in Mildly Symptomatic Outpatients With SARS-CoV-2 Infection Clustering-Aided Approach for Predicting Patient Outcomes with Application to Elderly Healthcare in Ireland A Fast Clustering Algorithm to Cluster Very Large Categorical Data Sets in Data Mining Extensions to the K-means Algorithm for Clustering Large Data Sets with Categorical Value Silhouettes: A Graphical Aid to the Interpretation and Validation of Cluster Analysis Clustering-Aided Approach for Predicting Patient Outcomes with Application to Elderly Healthcare in Ireland The Application of Unsupervised Clustering Methods to Alzheimer's Disease Approach and Method for Generating Realistic Synthetic Electronic Healthcare Records for Secondary Use Cluster analysis and its application to healthcare claims data: a study of end-stage renal disease patients who initiated hemodialysis Given the low availability of infected Covid-19 patients clinical data, it is challenging to understand and comprehend similar and complex patterns in these symptomatic patients.
    keywords: cases; covid; data; license; population; preprint; risk; symptoms
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        item: #6500 of 7819
          id: cord-339504-8svo2w3u
      author: Lima, Rodrigo Moreira e
       title: Recommendations for local-regional anesthesia during the COVID-19 pandemic
        date: 2020-06-10
       words: 2843
      flesch: 33
     summary: Regional anesthesia is not contra-indicated for COVID-19 positive patients. [24, 25] Anesthesia can be performed with routine care for COVID-19 negative patients who are not at risk.
    keywords: anesthesia; blocks; covid-19; disease; mask; patients; risk
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        item: #6501 of 7819
          id: cord-339506-pkusvf82
      author: Zaki, N.
       title: The estimations of the COVID-19 incubation period: a systematic review of the literature
        date: 2020-05-23
       words: 5976
      flesch: 47
     summary: key: cord-339506-pkusvf82 authors: Zaki, N.; Mohamed, E. A. title: The estimations of the COVID-19 incubation period: a systematic review of the literature date: 2020-05-23 journal: nan DOI: 10.1101/2020.05.20.20108340 sha: doc_id: 339506 cord_uid: pkusvf82 Objective: to undertake a review and critical appraisal of all published/preprint reports that offer an estimation of incubation periods for novel coronavirus (COVID-19). Accurately estimating the length of incubation period is essential for effective contemporary public health measures to be taken [2] .
    keywords: covid-19; data; days; incubation; incubation period; patients; period; research; transmission
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        item: #6502 of 7819
          id: cord-339509-4ezt6o0o
      author: Fox, Sharon E.
       title: Cardiac Endotheliitis and Multisystem Inflammatory Syndrome After COVID-19
        date: 2020-07-29
       words: 954
      flesch: 38
     summary: Similar inflammation was noted in occasional portal triad vessels within the liver (Figure, G) . key: cord-339509-4ezt6o0o authors: Fox, Sharon E.; Lameira, Fernanda S.; Rinker, Elizabeth B.; Vander Heide, Richard S. title: Cardiac Endotheliitis and Multisystem Inflammatory Syndrome After COVID-19 date: 2020-07-29 journal: Ann Intern Med DOI: 10.7326/l20-0882 sha: doc_id: 339509 cord_uid: 4ezt6o0o nan Background: Endotheliitis and microangiopathy have been identified as key features of the pathophysiology of severe coronavirus disease 2019 (COVID-19) (1, 2) .
    keywords: cardiac; covid-19; figure; syndrome
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        item: #6503 of 7819
          id: cord-339517-93nuovsj
      author: Consolo, Ugo
       title: Epidemiological Aspects and Psychological Reactions to COVID-19 of Dental Practitioners in the Northern Italy Districts of Modena and Reggio Emilia
        date: 2020-05-15
       words: 5657
      flesch: 46
     summary: Section 3 was composed of questions investigating the impact of the COVID-19 outbreak on dental practice, which were the most common protective personal equipment (PPE) used before the COVID-19 outbreak and whether habitual PPE had been changed after the outbreak. We also investigated the association between the impact of COVID-19 on dental practice and level of concern about the professional future.
    keywords: anxiety; covid-19; dental; dentists; future; infection; pandemic; patients; survey
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        item: #6504 of 7819
          id: cord-339533-r0qsqjus
      author: Mein, Stephen A
       title: COVID-19 and Health Disparities: the Reality of “the Great Equalizer”
        date: 2020-05-14
       words: 1112
      flesch: 47
     summary: Racial and ethnic minorities are at both a higher risk of contracting COVID-19 and suffering worse outcomes. 5 They are also more commonly single-income families, and a greater dependence on their income may leave them continuing jobs that place them at a higher risk of contracting COVID-19.
    keywords: covid-19; disease; health
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        item: #6505 of 7819
          id: cord-339536-je7fe0e7
      author: Chang, Wei-Ting
       title: The impact of COVID-19 on the research and educational environment in Taiwan --Forewarned is forearmed
        date: 2020-08-11
       words: 472
      flesch: 52
     summary: Press releases Working in Solidarity to Safeguard Taiwan--A Letter to Faculty Members, Staff, and Students Community Pharmacists in Taiwan at the Frontline Against the Novel Coronavirus Pandemic: Gatekeepers for the Rationing of Personal Protective Equipment key: cord-339536-je7fe0e7 authors: Chang, Wei-Ting; Hughes, Michael W.; Liu, Ping-Yen title: The impact of COVID-19 on the research and educational environment in Taiwan --Forewarned is forearmed date: 2020-08-11 journal: J Formos Med Assoc DOI: 10.1016/j.jfma.2020.08.004 sha: doc_id: 339536 cord_uid: je7fe0e7 nan The Coronavirus Disease-2019 (COVID-19) is an infectious disease caused by the virus of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) 1 .
    keywords: covid-19; taiwan
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        item: #6506 of 7819
          id: cord-339550-0yrb4qrh
      author: Félix-Oliveira, Afonso
       title: Caring for cardiac patients amidst the SARS-CoV-2 pandemic: The scrambled pieces of the puzzle
        date: 2020-04-23
       words: 751
      flesch: 50
     summary: Although the anticipated bottleneck in the care of COVID-19 patients was ICU beds and ventilators, healthcare workers, including cardiology professionals, are being assigned to tasks unrelated to their specialized training in order to compensate for the structural shortage of human resources in healthcare. This situation poses unique challenges for the care of non-COVID-19 patients, with unpredictable short-and long-term consequences, and a concerted strategy to mitigate these effects must be put in place.
    keywords: april; covid-19; patients
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        item: #6507 of 7819
          id: cord-339561-sgbxzeuh
      author: Snow, Elaine K
       title: Creation and maintenance of a table for assessment of evolving evidence for COVID-19–related treatments
        date: 2020-09-21
       words: 2099
      flesch: 45
     summary: The editorial team continued to add new therapies to the table and update existing entries as new evidence emerged. In response to the global COVID-19 pandemic, these skills were applied to assess emerging evidence for COVID-19–related treatments, and the information was compiled into a new resource for pharmacists and other healthcare professionals to use at the point of care.
    keywords: covid-19; evidence; information; table
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        item: #6508 of 7819
          id: cord-339576-0d6sa9pe
      author: Guallar, María Pilar
       title: Inoculum at the time of SARS-CoV-2 exposure and risk of disease severity
        date: 2020-06-14
       words: 1381
      flesch: 48
     summary: For COVID-19, high viral loads either in saliva, respiratory secretions or blood have been associated with more severe illness [3, 4] . A relationship between the infecting dose and the risk of disease severity has been demonstrated for several viral infections, including influenza and SARS [1, 2] .
    keywords: cluster; covid-19; exposure; sars
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        item: #6509 of 7819
          id: cord-339579-4n43at58
      author: Lan, Lan
       title: Early CT Findings of Coronavirus Disease 2019 (COVID-19) in Asymptomatic Children: A Single-Center Experience
        date: 2020-04-22
       words: 2233
      flesch: 41
     summary: As most pediatric patients were mild or moderate cases of COVID-19, the rate DISCUSSION A low percentage (0.4%, 6 of the 1574 patients) of pediatric patients aged less than 14 years was diagnosed with COVID-19 in our center, which was consistent with the results previously reported by Guan et al. Although similar to adult patients, pediatric patients tended to experience mild manifestations of COVID-19.
    keywords: covid-19; disease; findings; patients
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        item: #6510 of 7819
          id: cord-339589-dl2qpc0t
      author: Thachil, Jecko
       title: SARS-2 Coronavirus–Associated Hemostatic Lung Abnormality in COVID-19: Is It Pulmonary Thrombosis or Pulmonary Embolism?
        date: 2020-05-12
       words: 2212
      flesch: 33
     summary: Since there is a crucial link between inflammation and thrombosis, more so in COVID-19 patients, are patients who are on immunosuppressants less likely to get severe pulmonary disease and complications? It is important to distinguish pulmonary microthrombi from pulmonary emboli in COVID-19 patients.
    keywords: covid-19; hemostasis; microthrombi; patients; pulmonary; thrombosis
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        item: #6511 of 7819
          id: cord-339614-28s205p8
      author: Dover, Jeffrey S.
       title: A Path to Resume Aesthetic Care: Executive Summary of Project AesCert Guidance Supplement—Practical Considerations for Aesthetic Medicine Professionals Supporting Clinic Preparedness in Response to the SARS-CoV-2 Outbreak
        date: 2020-05-01
       words: 12539
      flesch: 32
     summary: Depending on the nature, duration and overall extent of the individual's activity in the office, including interactions with other patients, employees and others, the practice may need to consider further prophylactic measures up to and including temporary office closure, in order to minimize further exposure, ensure adequate site remediation, and assess the risk of further transmission. For all these reasons, consider limiting all such AGPs to one or more designated treatment rooms with appropriate air handling, containment and evacuation systems, in order to avoid exposing other treatment rooms or office areas.
    keywords: care; contact; covid-19; exposure; face; guidance; health; mask; office; patient; ppe; practice; procedures; risk; room; safety; staff; time; treatment; treatment room; use
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        item: #6512 of 7819
          id: cord-339616-4ctpq5v3
      author: de Carvalho, Carolina Abreu
       title: How is Brazil facing the crisis of Food and Nutrition Security during the COVID-19 pandemic?
        date: 2020-10-12
       words: 2757
      flesch: 42
     summary: Therefore, although no interruption in food supply occurred, Brazilians with compromised incomes during the pandemic may have problems accessing food as they are unable to afford it. The fight against food insecurity in Brazil was interrupted with the adoption of austerity measures, such as the National Amendment 95/2016 (4) , which reduced public expenditure on social policies, in addition to labour and social security reforms, which represents a scenario of violation of human rights that are being aggravated by the current pandemic.
    keywords: brazil; covid-19; fns; food; nutrition; pandemic
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        item: #6513 of 7819
          id: cord-339637-hb6bsb6q
      author: Khader, Mohammed Abdul
       title: A cross sectional study reveals severe disruption in glycemic control in people with diabetes during and after lockdown in India
        date: 2020-08-18
       words: 3804
      flesch: 51
     summary: A pilot study from Government medical university reported 4880 teleconsultations were given by 38 ophthalmologists during COVID-19 lockdown in India However, since the start of unlocking and easing of restrictions from June 1 st , India is witnessing an exponential rise in COVID-19 cases indicating the possibility of 'community transmission' [2] .
    keywords: care; covid-19; diabetes; india; pandemic; participants; people; study
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        item: #6514 of 7819
          id: cord-339638-yrxoj1hl
      author: Goldman, Ran D.
       title: Willingness to Vaccinate Children against Influenza after the COVID-19 Pandemic
        date: 2020-08-07
       words: 3507
      flesch: 37
     summary: Public Health officials will need to ensure clear messaging on the safety of influenza vaccines next year, especially in face of COVID-19, to influence parental decision making to convert into vaccinating children. Caregivers were more likely to change from non-vaccination last year to vaccination in the coming year when they had education more than high-school, they took the vaccine themselves or planning to get vaccinated themselves next year, had a child with an up-to-date vaccination schedule excluding influenza vaccines or were worried their child may have COVID-19 or influenza during the visit in the ED.
    keywords: caregivers; children; covid-19; influenza; vaccination; vaccine; year
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        item: #6515 of 7819
          id: cord-339645-0babe90b
      author: Stewart, Ruth
       title: Evidence synthesis communities in low-income and middle-income countries and the COVID-19 response
        date: 2020-10-20
       words: 1072
      flesch: 42
     summary: As a network we have accelerated investment to enable infrastructure for evidence synthesis and to promote evidence use. We need action from individuals, organisations, govern ments, and donors to enable and sustain the generation and use of evidence synthesis in LMICs if we are to tackle COVID-19 globally.
    keywords: covid-19; evidence; pandemic; synthesis
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        item: #6516 of 7819
          id: cord-339649-ppgmmeuz
      author: Klein, Michael G.
       title: COVID-19 Models for Hospital Surge Capacity Planning: A Systematic Review
        date: 2020-09-10
       words: 4188
      flesch: 45
     summary: The results of our study provide information to physicians, hospital administrators, emergency response personnel, and governmental agencies on available models for preparing scenario-based plans for responding to the COVID-19 or similar type of outbreak. In this systematic review, we identified and reviewed surge capacity planning models that handle both caseload projection and hospital capacity management for this novel pandemic disease.
    keywords: capacity; covid-19; hospital; model; parameters; patients; planning; surge; tool
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        item: #6517 of 7819
          id: cord-339665-nwwutduy
      author: Patel, Ami
       title: Intradermal-delivered DNA vaccine provides anamnestic protection in a rhesus macaque SARS-CoV-2 challenge model
        date: 2020-07-29
       words: 5279
      flesch: 44
     summary: This vaccine candidate induced neutralizing and ACE2-blocking antibodies, as well as T cell responses in mice and guinea pigs. This anamnestic response was characterized by expansion of neutralizing antibody responses, including those against the now dominantly circulating G614 variant, as well as the rapid expansion of T cell responses.
    keywords: animals; cells; challenge; cov-2; covid-19; et al; ino-4800; protein; responses; sars; spike; vaccine
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        item: #6518 of 7819
          id: cord-339686-oybnk1j8
      author: Suassuna, José Hermógenes Rocco
       title: Technical note and clinical instructions for Acute Kidney Injury (AKI) in patients with Covid-19: Brazilian Society of Nephrology and Brazilian Association of Intensive Care Medicine
        date: 2020-08-26
       words: 5774
      flesch: 37
     summary: These data did not suggest a higher incidence of AKI in patients with Covid-19 when compared to other patients with the same severity profile 17 . For this reason, there was an initial recommendation to restrict the entry of nephrologists and dialysis nurses in the cohorts allocated Covid-19 patients.
    keywords: acute; aki; care; cases; clinical; cov-2; covid-19; dialysis; injury; kidney; patients; renal; risk; rrt; sars
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        item: #6519 of 7819
          id: cord-339689-pemyxewv
      author: Moran, Alexander
       title: Learning from tuberculosis: COVID-19 highlights the need for more robust infection control policy
        date: 2020-07-28
       words: 2696
      flesch: 37
     summary: TB is the biggest infectious disease killer globally and, while COVID-19 is a global public health emergency, we must maintain this urgency and momentum for TB IPC after the threat has passed. In the wake of World TB Day and in the context of a rapidly moving pandemic, there is no better resource for high burden TB countries than national TB control programs.
    keywords: africa; control; countries; covid-19; health; ipc
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        item: #6520 of 7819
          id: cord-339695-3ij5pjjy
      author: Nopp, Stephan
       title: Risk of venous thromboembolism in patients with COVID‐19: A systematic review and meta‐analysis
        date: 2020-09-25
       words: 4717
      flesch: 36
     summary: All rights reserved Pulmonary Embolism in COVID-19 Patients: Awareness of an Increased Prevalence Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Acute Pulmonary Embolism Associated with COVID-19 Pneumonia Detected by Pulmonary CT Angiography Venous Thromboembolism in Critically Ill Patients with Covid-19: Results of a Screening Study for Deep Vein Thrombosis Clinical Characteristics of Covid-19 in Remdesivir for the Treatment of Covid-19 -Preliminary Report Impact of anticoagulation prior to COVID-19 infection: a propensity score-matched cohort study Anakinra for severe forms of COVID-19: a cohort study Venous Thrombosis Among Critically Ill Patients With Coronavirus Disease 2019 ( Therefore, the true underlying burden of VTE in COVID-19 patients is still not fully understood.
    keywords: analysis; covid-19; data; icu; patients; rates; risk; studies; study; vte
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        item: #6521 of 7819
          id: cord-339701-j0sr3ifq
      author: Mikami, Takahisa
       title: Risk Factors for Mortality in Patients with COVID-19 in New York City
        date: 2020-06-30
       words: 3409
      flesch: 38
     summary: Compared with that of ambulatory patients, a higher proportion of hospitalized patients were older, were male, or had a history of cigarette use. A multicenter retrospective cohort study of patients with COVID-19 patients was conducted using the medical records of the Mount Sinai Health System, a large urban health system of 8 hospitals and more than four hundred ambulatory practices in the New York City metropolitan area.
    keywords: covid-19; hydroxychloroquine; mortality; non; patients; risk; study; survivors
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        item: #6522 of 7819
          id: cord-339712-chkgq0it
      author: Hussain, Arshad
       title: People with Diabetes Mellitus: Soft target for COVID-19 infection
        date: 2020-05-17
       words: 1566
      flesch: 47
     summary: A high case fatality rate (73.3%) has been observed in COVID-19 patients with underlying diseases. These results are in agreement with the article published on DM patients infected with avian influenza whereby hyperglycemia was associated with a poor outcome.
    keywords: covid-19; diabetes; disease; patients
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        item: #6523 of 7819
          id: cord-339727-q8pjwl3s
      author: Sahu, Kamal Kant
       title: Mesenchymal Stem Cells in COVID-19: A Journey from Bench to Bedside
        date: 2020-07-30
       words: 3331
      flesch: 40
     summary: Pictorial description of the source of stem cells, and impact of mesenchymal stem cells. LM Current perspective on pandemic of COVID-19 in the United States A new coronavirus associated with human respiratory disease in China Preventive and treatment strategies of COVID-19: from community to clinical trials Coronavirus update (Live): 6,102,522 cases and 369,127 deaths from COVID-19 virus pandemic -worldometer website updated SARS-CoV-2 vaccines: status report Novel coronavirus 2019 (COVID-19): a case report and review of treatments Cell-based therapy to reduce mortality from COVID-19: Systematic review and meta-analysis of human studies on acute respiratory distress syndrome Immunomodulation by Mesenchymal Stem Cells (MSCs): mechanisms of action of living, apoptotic, and dead MSCs Convalescent plasma therapy: a passive therapy for an aggressive COVID-19 Latest updates on COVID-2019: a changing paradigm shift Transplantation of ACE2-mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia Mesenchymal stem cell therapy for COVID-19: present or future Mesenchymal stem cells and management of COVID-19 pneumonia Mesenchymal stem cells as a potential therapy for COVID-19 Mesenchymal stem cells as therapeutics Expanded umbilical cord mesenchymal stem cells (UC-MSCs) as a therapeutic strategy in managing critically ill COVID-19 patients: the case for compassionate use Stem cell therapy for preventing neonatal diseases in the 21st century: Current understanding and challenges Mesenchymal stem cells for coronavirus (COVID-19)-induced pneumonia: revisiting the paracrine hypothesis with new hopes? Mesenchymal stem cell infusion shows promise for combating coronavirus (COVID-19)-induced pneumonia Mesenchymal stem cells in tumor development: emerging roles and concepts Mesenchymal stem cells as regulators of carcinogenesis Clarifying stem-cell therapy's benefits and risks FDA warns about stem cell therapies | FDA.
    keywords: cells; coronavirus; covid-19; mesenchymal; mscs; patients; sars; stem; therapy
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        item: #6524 of 7819
          id: cord-339737-7qdjea6f
      author: Sbidian, E.
       title: Hydroxychloroquine with or without azithromycin and in-hospital mortality or discharge in patients hospitalized for COVID-19 infection: a cohort study of 4,642 in-patients in France
        date: 2020-06-19
       words: 6053
      flesch: 37
     summary: For all IPT-weighting based analyses, standardized differences of the means were computed before and after IPTW to assess imbalance of the covariates between treatment groups. Table 2 shows unadjusted clinical outcomes by treatment group.
    keywords: azi; covid-19; day; discharge; drug; hcq; license; medrxiv; mortality; patients; preprint; treatment
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        item: #6525 of 7819
          id: cord-339830-7om9ajev
      author: Fisher, Edwin B
       title: COVID-19, stress, trauma, and peer support—observations from the field
        date: 2020-06-22
       words: 1619
      flesch: 44
     summary: As it was going to press, we had the opportunity (April 24, 2020) to talk about the impacts of COVID-19 with peer support workers from three of these, Mom2Mom, Worker2Worker, and Cop2Cop. Especially among police, peer support workers described their callers getting through this difficult period by trying to keep doing their business … keeping their minds busy and trying not to think about COVID-19 too much.
    keywords: child; covid-19; peer; support; workers
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        item: #6526 of 7819
          id: cord-339835-ze9ay2rm
      author: Daphna-Tekoah, Shir
       title: Listening to Hospital Personnel’s Narratives during the COVID-19 Outbreak
        date: 2020-09-03
       words: 7908
      flesch: 50
     summary: It was against this background that hospital HCWs the world over first encountered the global COVID-19 pandemic in December 2019 In light of the findings of this study, we recommend that leaders in the health care system should identify hospital HCWs as first responders (similar to combatants in the traditional military environment).
    keywords: coronavirus; covid-19; guide; hcws; health; hospital; listening; needs; pandemic; patients; staff; workers
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        item: #6527 of 7819
          id: cord-339861-yq1qeo5d
      author: Fan, Jingchun
       title: The Epidemiology of COVID-19 in the Gansu and Jinlin Provinces, China
        date: 2020-09-11
       words: 4516
      flesch: 42
     summary: It has been striking to observe that these measures were able to substantially reduce the number of COVID-19 cases to close to zero within a month, i.e., by February 2020 (9) . As the preferred place for receiving Chinese returnees by the Chinese authority, Lanzhou city has received a total of 311 evacuated Chinese citizens from Iran, amongst whom there has been 37 confirmed positive cases of COVID-19 infection, which were only discovered shortly after arrival in Lanzhou (32) .
    keywords: cases; china; control; covid-19; gansu; jilin; outbreak; province
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        item: #6528 of 7819
          id: cord-339864-rv5zw972
      author: Reihani, Hamidreza
       title: Non-evidenced based treatment: An unintended cause of morbidity and mortality related to COVID-19
        date: 2020-05-06
       words: 1012
      flesch: 41
     summary: In silico screening of Chinese herbal medicines with the potential to directly inhibit 2019 novel coronavirus Traditional Chinese herbal medicine for treating novel coronavirus (COVID-19) pneumonia: protocol for a systematic review and meta-analysis Toxicities by herbal medicines with emphasis to traditional Chinese medicine Misinformation and false medical advice spreads in Iran Risk Communication: EPI-WIN World Health Organization. Use of Chinese herbal products for treating viruses is not guided by viral pathology, rather herbs are prescribed by herbalists according to Chinese diagnostic patterns (inspection, listening, smelling, inquiry, and palpitation)
    keywords: coronavirus; covid-19; health; herbal
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        item: #6529 of 7819
          id: cord-339874-not2z6q6
      author: Kumar, Ankush
       title: Modeling geographical spread of COVID-19 in India using network-based approach
        date: 2020-04-27
       words: 2332
      flesch: 47
     summary: We anticipate that the state Kerala, with one of the highest cases of COVID-19, may not receive significant incoming cases, while Karnataka and Haryana may receive the challenge of high incoming cases, with medium cases so far. We found that migration towards native places may result in higher incoming cases in Uttar Pradesh and Bihar, while migration to the professional sites can surge incoming cases in Karnataka, Maharashtra, and Haryana, and daily flows are likely to endanger both sets of sites.
    keywords: cases; covid-19; migration; mobility; number
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        item: #6530 of 7819
          id: cord-339902-tsd6sjcx
      author: Lagunas-Rangel, F. A.
       title: Laboratory findings that predict a poor prognosis in COVID-19 patients with diabetes: A meta-analysis
        date: 2020-07-04
       words: 995
      flesch: 46
     summary: key: cord-339902-tsd6sjcx authors: Lagunas-Rangel, F. A.; Chavez-Valencia, V. title: Laboratory findings that predict a poor prognosis in COVID-19 patients with diabetes: A meta-analysis date: 2020-07-04 journal: nan DOI: 10.1101/2020.07.02.20145391 sha: doc_id: 339902 cord_uid: tsd6sjcx Diabetes is one of the main comorbidities in patients infected with the SARS-CoV-2 virus, the causative agent of the new coronavirus disease 2019 (COVID-19). In this way, in the present work we analyze which laboratory parameters showed differences in patients with COVID-19 and diabetes who recovered and in those who had complications or died.
    keywords: covid-19; diabetes; patients
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        item: #6531 of 7819
          id: cord-339908-a2r5wzqn
      author: Rajkumar, Ravi Philip
       title: Sleep, physical activity and mental health during the COVID-19 pandemic: complexities and opportunities for intervention
        date: 2020-10-10
       words: 1163
      flesch: 17
     summary: J o u r n a l P r e -p r o o f Sleep and circadian rhythm in response to the COVID-19 pandemic Impact of COVID-19 lockdown on sleep-wake schedule and associated lifestyle related behavior: a national survey Prevalence of stress, anxiety, depression among the general population during the COVID-19 pandemic: a systematic review and meta-analysis Impact of COVID-19 pandemic on mental health in the general population: a systematic review Prevalence of psychological morbidities among general population, healthcare workers and COVID-19 patients amidst the COVID-19 pandemic: a systematic review Sleep quality and mental health in the context of COVID-19 pandemic and lockdown in Morocco Determinants of the lifestyle changes during COVID-19 pandemic in the residents of Northern Italy Trophic mechanisms for exercise-induced stress resilience: potential role of interactions between BDNF and galanin Psychological resilience during the COVID-19 lockdown Mental health and sleep disturbances in physically active adults during the COVID-19 lockdown in Norway: does change in physical activity level matter Physical activity protects from incident anxiety: a meta-analysis of prospective cohort studies The effects of physical activity on sleep: a meta-analytic review Poor sleep quality increases symptoms of depression and anxiety in postpartum J o u r n a l P r e -p r o o f women Sleep quality and its association with psychological distress and sleep hygiene: a cross-sectional study among pre-clinical medical students Dissassembling insomnia symptoms and their associations with depressive symptoms in a community sample: the differential role of sleep symptoms, daytime symptoms, and perception symptoms of insomnia The enemy who sealed the world: effects quarantine due to the COVID-19 on sleep quality, anxiety, and psychological distress in the Italian population Sleep disturbances among Chinese residents during the Coronavirus Disease 2019 outbreak and associated factors COVID-19 related loneliness and sleep problems in older adults: worries and resilience as potential moderators E-mental health mindfulness-based and skills-based 'CoPE It' intervention to reduce psychological distress in times of COVID-19: study protocol for a bicentre longitudinal study Testing an early online intervention for the treatment of disturbed sleep during the COVID-19 pandemic (Sleep COVID-19): structured summary of a study protocol for a randomised controlled trial The author reports no funding sources for the work presented in this paper. From a theoretical and empirical perspective, physical activity improves both mental health and sleep quality [8, 11, 12] ; good sleep quality ameliorates symptoms of anxiety and depression
    keywords: covid-19; sleep
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        item: #6532 of 7819
          id: cord-339919-4ko4lwjz
      author: Cook, T. M.
       title: The importance of hypertension as a risk factor for severe illness and mortality in COVID‐19
        date: 2020-05-09
       words: 670
      flesch: 34
     summary: Receptor recognition by novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical characteristics of coronavirus disease 2019 in China Clinical course and outcomes of 344 intensive care patients with COVID-19. Hypertension is included in many reports as a 'risk factor' for COVID-19 but there has been a lack of clarity as to whether this means risk factor for acquiring the disease, the severity of disease or for poor outcomes.
    keywords: disease; hypertension
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        item: #6533 of 7819
          id: cord-339935-tguhrqvz
      author: Zavattaro, Staci M.
       title: Introduction: COVID‐19 Viewpoint Symposium, Part II
        date: 2020-08-12
       words: 2245
      flesch: 37
     summary: For instance, while our contributors were intentionally global, voices from the Global South need amplification regarding pandemic response. Also, while some of the authors noted the cultural differences between countries and pandemic response, more could be done regarding administrative functions within those varied systems.
    keywords: covid-19; crisis; pandemic; research; response
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        item: #6534 of 7819
          id: cord-339956-o5o2yz1u
      author: Albahri, O.S.
       title: Helping Doctors Hasten COVID-19 Treatment: Towards a Rescue Framework for the Transfusion of Best Convalescent Plasma to the Most Critical Patients based on Biological Requirements via ML and Novel MCDM Methods
        date: 2020-06-20
       words: 8697
      flesch: 42
     summary: Firstly, weights are assigned to the serological/protein biomarker and PaO 2 /FiO 2 criteria used in the prioritisation of CPs and COVID-19 patients. This stage aims to eliminate two critical issues (i.e. multi-criteria and trade-off issues) through ranking alternatives (i.e. CPs and/or COVID-19 patients).
    keywords: basis; blood; covid-19; cps; criteria; criterion; decision; evaluation; framework; matrix; mcdm; methods; multi; patients; plasma; prioritisation; protein
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        item: #6535 of 7819
          id: cord-339968-s1kmipir
      author: Osier, Faith
       title: The global response to the COVID-19 pandemic: how have immunology societies contributed?
        date: 2020-09-10
       words: 6130
      flesch: 32
     summary: Finally, SIICA and other European immunology societies strongly endorsed the GAVI advanced market commitment for COVID-19 vaccines (COVAX AMC), which is an initiative to support the development of a COVID-19 vaccine through multilateral, international collaborations 46 . BSI 'Connect on Coronavirus' webinar series CSI Council statement on systemic inequities A peptide-based magnetic chemiluminescence enzyme immunoassay for serological diagnosis of coronavirus disease 2019 Diagnosis of acute respiratory syndrome coronavirus 2 infection by detection of nucleocapsid protein Rapid development of an inactivated vaccine candidate for SARS-CoV-2 Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial Human monoclonal antibodies block the binding of SARS-CoV-2 spike protein to angiotensin converting enzyme 2 receptor Potent neutralizing antibodies against SARS-CoV-2 identified by high-throughput single-cell sequencing of convalescent patients' B cells A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice Generation of a broadly useful model for COVID-19 pathogenesis, vaccination, and treatment Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19) Antibody responses to SARS-CoV-2 in patients with COVID-19 Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
    keywords: cov-2; covid-19; health; immunologists; immunology; information; members; pandemic; patients; public; research; sars; societies; society; vaccine
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        item: #6536 of 7819
          id: cord-339984-vuwjre82
      author: Nair, Vinay
       title: COVID-19 and solid organ transplant outcomes
        date: 2020-09-02
       words: 1302
      flesch: 44
     summary: Early description of coronavirus 2019 disease in kidney transplant recipients in New York COVID-19 in solid organ transplant recipients: a single-center case series from Spain Covid-19 and kidney transplantation COVID-19 in solid organ transplant recipients: initial report from the US Epicenter COVID-19 in kidney transplant recipients UK and 3 Renal Unit, Barts and the London NHS Trust Their use will therefore increase over time [6, 7] . Identification of kidney transplant recipients with coronavirus disease 2019 Coronavirus disease 2019 pneumonia in immunosuppressed renal transplant recipients: a summary of 10 confirmed cases in Wuhan, China COVID-19 infection in kidney transplant recipients A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia The Columbia University Kidney Transplant Program.
    keywords: covid-19; recipients; studies; transplant
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        item: #6537 of 7819
          id: cord-339990-gtbhb24z
      author: Moroni, Francesco
       title: COVID-19 and arterial thrombosis: A potentially fatal combination
        date: 2020-10-20
       words: 960
      flesch: 30
     summary: On the contrary, laboratory test alterations typically hallmarking DIC, including low platelet count, prothrombin time prolongation, and fibrinogen consumption are often mild or lacking in COVID-19 patients experiencing thrombotic events. This figure is even higher than the 3.7-4.4% reported in the largest previously published cohorts on COVID-19 patients.
    keywords: anticoagulation; covid-19; events; patients
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        item: #6538 of 7819
          id: cord-340008-2efzyki4
      author: Haddadi, Kaveh
       title: Coronavirus Disease 2019: Latest Data on Neuroinvasive Potential
        date: 2020-09-17
       words: 3586
      flesch: 34
     summary: Neuroscience CD40-CD40L interactions induce chemokine expression by human microglia: implications for human immunodeficiency virus encephalitis and multiple sclerosis Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding From SARS to MERS, Thrusting Coronaviruses into the Spotlight Receptor Recognition by the Novel Coronavirus from Wuhan: an Analysis Based on Decade-Long Structural Studies of SARS Coronavirus Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice Coronavirus infection of rat dorsal root ganglia: ultrastructural characterization of viral replication, transfer, and the early response of satellite cells Immunofluorescence studies on the pathogenesis of hemagglutinating encephalomyelitis virus infection in pigs after oronasal inoculation Neurotropic virus tracing suggests a membranous-coatingmediated mechanism for transsynaptic communication Characteristics of a coronavirus (strain 67N) of pigs Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways Detection of severe acute respiratory syndrome coronavirus in the brain: potential role of the chemokine mig in pathogenesis Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4 Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9 Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. She presented with respiratory manifestations and computed tomography scanconfirmed lung involvement typically matched by COVID-19 infection.
    keywords: cells; cns; coronavirus; cov-2; covid-19; infection; manifestations; patients; sars
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        item: #6539 of 7819
          id: cord-340010-t1m7dxzc
      author: Schaefer, Esperance A. K.
       title: Interrelationship Between Coronavirus Infection and Liver Disease
        date: 2020-05-21
       words: 1422
      flesch: 32
     summary: The immune response to SARS-CoV-2 is characterized by very high levels of IL-6, 33 which has been implicated in both the inflammatory and the repair responses in liver disease. First, there is often uncertainty whether there is preexisting undiagnosed liver disease.
    keywords: covid-19; disease; injury; liver; patients
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        item: #6540 of 7819
          id: cord-340015-x9frt0jh
      author: de Carvalho, Werther Brunow
       title: Expert recommendations for the care of newborns of mothers with COVID-19
        date: 2020-05-11
       words: 2823
      flesch: 42
     summary: Date of Document Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records A case of 2019 Novel Coronavirus in a pregnant woman with preterm delivery Considerations for Inpatient Obstetric Healthcare Settings Recomendaciones para el manejo del recién nacido en relatión con la infección por SARS-CoV-2 Coronavirus (COVID-19) Infection in Pregnancy. High-risk exposure is defined as a person with COVID-19 disease requiring direct physical or close contact (o1.8 meters) for an extended time.
    keywords: care; contact; coronavirus; covid-19; infection; mothers; newborns
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        item: #6541 of 7819
          id: cord-340027-6l55rcfm
      author: Mamode Khan, Naushad
       title: Studying the trend of the novel coronavirus series in Mauritius and its implications
        date: 2020-07-10
       words: 3629
      flesch: 43
     summary: This paper proposes an integer-valued time series model to analyze the series of COVID-19 cases in Mauritius wherein the corresponding innovation term accommodates for covariate specification. Based on the proposed COM-Poisson mixture models, we could predict the number of COVID-19 cases in Mauritius.
    keywords: cases; covid-19; health; mauritius; model; number; y t
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        item: #6542 of 7819
          id: cord-340028-6oicmeam
      author: Zhavoronkov, Alex
       title: Geroprotective and senoremediative strategies to reduce the comorbidity, infection rates, severity, and lethality in gerophilic and gerolavic infections
        date: 2020-03-31
       words: 7232
      flesch: 30
     summary: However, it may be possible to conduct clinical trials on the efficacy of geroprotectors previously tested in human clinical trials in treating COVID-19 and other gerophilic and gerolavic infections. Substantial pre-clinical validation would be required to apply these compounds to specific age-associated diseases and to explore clinical applications of these compounds in human clinical trials.
    keywords: age; aging; covid-19; disease; effects; gerolavic; immunosenescence; infection; influenza; nad; patients; rapamycin; sars; severity; treatment; trials
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        item: #6543 of 7819
          id: cord-340029-iv2x1vap
      author: Farabi, Banu
       title: Comment on “Psoriasis, COVID‐19 and acute respiratory distress syndrome: focusing on the risk of concomitant biological treatment”
        date: 2020-06-14
       words: 814
      flesch: 22
     summary: COVID-19 and acute respiratory distress syndrome: focusing on the risk of concomitant biological treatment Evolution of COVID-19 infection in 4 psoriatic patients treated with biological drugs Biologics for psoriasis patients in the COVID-19 era: more evidence, less fears Risk of hospitalization and death from COVID-19 infection in patients with chronic plaque psoriasis receiving a biological treatment and renal transplanted recipients in maintenance immunosuppressive treatment COVID-19 and psoriasis: Is it time to limit treatment with immunosuppressants? Various scientific societies like American Academy of Dermatology (AAD) and International League of Dermatological Societies (ILDS) have issued guidelines to discontinue only in COVID-19 positive patients but can be carefully considered on a case-by-case basis if the patient is COVID-19 negative and with no symptoms by weighing risk vs. benefit ratio.
    keywords: covid-19; patients; psoriasis
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        item: #6544 of 7819
          id: cord-340042-intxyu46
      author: Chaudhry, Sundas Nasir
       title: New insight on possible vaccine development against SARS-CoV-2
        date: 2020-09-11
       words: 5470
      flesch: 31
     summary: A pneumonia outbreak associated with a new coronavirus of probable bat origin Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology Immune responses in COVID-19 and potential vaccines: Lessons learned from SARS and MERS epidemic Coronavirus infections and immune responses SARS and MERS: recent insights into emerging coronaviruses Coronavirus endoribonuclease activity in porcine epidemic diarrhea virus suppresses type I and type III interferon responses The outbreak of SARS-CoV-2 pneumonia calls for viral vaccines Research and development on therapeutic agents and vaccines for COVID-19 and related human coronavirus diseases The race for coronavirus vaccines: a graphical guide The socio-economic implications of the coronavirus and COVID-19 pandemic: a review SARS-CoV-2 vaccines: status report Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen COVID-19 vaccine development pipeline gears up SARS-CoV-2/COVID-19: Viral genomics, epidemiology, vaccines, and therapeutic interventions The recombinant N-terminal domain of spike proteins is a potential vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infection Development of an inactivated vaccine candidate for SARS-CoV-2 A preliminary study on serological assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 238 admitted hospital patients Vaccination strategies to combat novel corona virus SARS-CoV-2 The ORF7b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is expressed in virus-infected cells and incorporated into SARS-CoV particles Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody Prevention and control of seasonal influenza with vaccines: recommendations of the Advisory Committee on Immunization Practices-United States, 2019-20 influenza season An oral live attenuated vaccine strategy against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/2019-nCoV) Evolution and containment of transmissible recombinant vector vaccines Progress and prospects on vaccine development against SARS-CoV-2, Vaccines Potential of live pathogen vaccines for defeating the COVID-19 pandemic: history and mechanism mRNA as a transformative technology for vaccine development to control infectious diseases Optimization of lipid nanoparticles for intramuscular administration of mRNA vaccines Race for a Coronavirus Vaccine: Thanks in part to institutional support Moderna Therapeutics, and other developers are exploring diverse approaches against SARS-CoV-2 SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness Leveraging mRNAs sequences to express SARS-CoV-2 antigens in vivo The novel coronavirus originating in Wuhan, China: challenges for global health governance Pre-fusion structure of a human coronavirus spike protein A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice Characterization and preclinical evaluation of the cGMP grade DNA based vaccine, AV-1959D to enter the first-in-human clinical trials Engineering DNA vaccines against infectious diseases DNA vaccine protection against SARS-CoV-2 in rhesus macaques Immunogenicity of a DNA vaccine candidate for COVID-19 Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, doseescalation trial Design of a heterosubtypic epitope-based peptide vaccine fused with hemokinin-1 against influenza viruses The role of the proteasome in generating cytotoxic T-cell epitopes: insights obtained from improved predictions of proteasomal cleavage A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Design of an Epitope-Based Peptide Vaccine against the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2): A Vaccine Informatics Approach Application of in-silico reverse vaccinology for designing multiepitope vaccine against Coronavirus Multi-epitope vaccine design using an immunoinformatics approach for 2019 novel coronavirus in China (SARS-CoV-2), bioRxiv The latest advancements in Zika virus vaccine development The Potency of an Anti-MERS Coronavirus Subunit Vaccine Depends on a Unique Combinatorial Adjuvant Formulation The SARS-CoV-2 vaccine pipeline: an overview, Current tropical medicine reports Clover initiates development of recombinant subunit-trimer vaccine for wuhan coronavirus A translatable subunit nanovaccine for COVID-19 Design of a peptide-based subunit vaccine Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections Angiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus Pharmacokinetics and pharmacodynamics of recombinant human angiotensin-converting enzyme 2 in healthy human subjects Potent neutralization of 2019 novel coronavirus by recombinant ACE2-Ig Protection of Rhesus Macaque from SARS-Coronavirus challenge by recombinant adenovirus vaccine Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19 Potential rapid diagnostics, vaccine and therapeutics for 2019 novel coronavirus (2019-nCoV): a systematic review A decade after SARS: strategies for controlling emerging coronaviruses New vaccine technologies to combat outbreak situations Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia Based on these points, the potential parts of S protein, which are used as antigens in immunization improvement, integrate the entire extent of this protein and vaccine development [57] .
    keywords: cell; coronavirus; cov-2; covid-19; development; immune; novel; protein; receptor; response; sars; spike; vaccine
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        item: #6545 of 7819
          id: cord-340051-r9kn34wd
      author: MEI, Xue
       title: Observations about Symptomatic and Asymptomatic infections of 494 patients with COVID-19 in Shanghai,China
        date: 2020-07-06
       words: 3228
      flesch: 46
     summary: METHODS: To retrospectively analyze the clinical data of 494 confirmed COVID-19 patients admitted to a designated hospital in Shanghai from January 20, 2020, to March 31, 2020, we compared the clinical manifestations in different populations and their influencing factors in COVID-19 patients. The majority of COVID-19 patients (91.7%) had early symptoms.
    keywords: acid; days; nucleic; patients; symptoms; test
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        item: #6546 of 7819
          id: cord-340060-l1okt3lm
      author: pathak, Mamta
       title: Global Threat of SARS-CoV-2/COVID-19 and the Need for More and Better Diagnostic Tools
        date: 2020-04-15
       words: 303
      flesch: 27
     summary: None. None. Practical Strategies Against the Novel Coronavirus and COVID-19-the Imminent Global Threat Going global-Travel and the 2019 novel coronavirus Rapid colorimetric detection of COVID-19 coronavirus using a reverse tran-scriptional loop-mediated isothermal amplification (RT-LAMP) diagnostic plat-form: iLACO Point-of-Care RNA-Based Diagnostic Device for COVID-19 Now with more than 1 million cases, the COVID-19 pandemic is leading to substantial economic losses, psychological and social impacts.
    keywords: covid-19
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        item: #6547 of 7819
          id: cord-340063-nmx91h0a
      author: Müller, Olaf
       title: Epidemiologie und Kontrollmaßnahmen bei COVID-19
        date: 2020-04-28
       words: 3027
      flesch: 45
     summary: Es ist momentan auch noch offen, welche Ausmaße die Pandemie in den Industrieländern erlangen wird; dies hängt primär von der Intensität und Dauer der durchgeführten Public-Health-Maßnahmen ab. Berechnungen zur Letalität von COVID-19 variieren bisher im
    keywords: als; auch; auf; bei; china; coronavirus; cov-2; covid-19; dass; den; der; die; einer; für; health; ist; maßnahmen; mit; nicht; sars; sind; und; von; werden; zur
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        item: #6548 of 7819
          id: cord-340085-ywg4rhnn
      author: Maras, J. S.
       title: Multi-Omics integration analysis of respiratory specimen characterizes baseline molecular determinants associated with COVID-19 diagnosis.
        date: 2020-07-07
       words: 7395
      flesch: 33
     summary: At the phylum level Proteobacteria and Tenericutes were increased, corroborating to an increase in alpha diversity seen in COVID-19 positive respiratory specimen ( Figure 4C , 4D, p<0.05 . Together these results show that multi-omics profile of COVID-19 positive respiratory specimen correlates with viraemia, provide an insight on immune activation and could also aid in the identification of asymptomatic COVID-19 patients.
    keywords: author; copyright; covid-19; funder; holder; july; license; medrxiv; medrxiv preprint; patients; perpetuity; preprint; version
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        item: #6549 of 7819
          id: cord-340090-dqhdws5k
      author: Behera, P.
       title: Role of ivermectin in the prevention of COVID-19 infection among healthcare workers in India: A matched case-control study
        date: 2020-11-03
       words: 3782
      flesch: 51
     summary: The study was aimed to explore the association between ivermectin prophylaxis and development of COVID-19 infection among healthcare workers. In the matched pair analysis, ivermectin prophylaxis (0.30, 95% CI, 0.16-0.53) was associated with the reduction of COVID-19 infection however vitamin-C prophylaxis (0.71, 95% CI, 0.40-1.26) and HCQ prophylaxis (0.58, 95% CI, 0.19-1.61) had no significant association with COVID-19 infection.
    keywords: covid-19; infection; ivermectin; medrxiv; preprint; prophylaxis; study
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        item: #6550 of 7819
          id: cord-340091-kptilmi8
      author: Mulatu, H. A.
       title: The prevalence of common mental disorders among health care professionals during the COVID-19 pandemic at a tertiary Hospital in East Africa
        date: 2020-11-03
       words: 4218
      flesch: 45
     summary: Frontline HCWs had higher scores of mental health symptoms than other health care workers. A recent study among 1257 healthcare professionals in a tertiary hospital in China, revealed a high prevalence of mental health symptoms among HCWs.
    keywords: anxiety; covid-19; depression; distress; insomnia; symptoms
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        item: #6551 of 7819
          id: cord-340094-u3x4g8ul
      author: D’Alò, Gian Loreto
       title: Microbial contamination of the surface of mobile phones and implications for the containment of the Covid-19 pandemic
        date: 2020-09-02
       words: 670
      flesch: 36
     summary: The development of research investigating MPs as vehicles of pathogens and their correlation with user habits could be useful to the World Health Organization (WHO) and to government agencies to increase public awareness and to formulate education material on MPs hygiene [3] . The actual increased societal awareness has led major MPs companies such as Apple, Samsung, and Google to release guidances for proper MPs disinfection
    keywords: covid-19; mps
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        item: #6552 of 7819
          id: cord-340103-dc3wye9s
      author: Pallanti, Stefano
       title: Importance of SARs-Cov-2 anosmia: From phenomenology to neurobiology
        date: 2020-05-11
       words: 2350
      flesch: 31
     summary: We now know that some infected patients, in addition to having respiratory symptoms, have exhibited neurological symptoms; signs of cerebral involvement have been shown in SARS-CoV-2, and the virus has been detected in the brains of infected patients. Neurological manifestations of COVID-19 in hospitalized patients are quite common (78 out J o u r n a l P r e -p r o o f of 214 patients; 36.4%), sometimes in the absence of other infection symptoms; and more severe patients were more likely to have neurological symptoms (45.5%), such as acute cerebrovascular diseases, impaired consciousness and induced skeletal muscle injury.
    keywords: anosmia; covid-19; patients; symptoms
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        item: #6553 of 7819
          id: cord-340110-nvjit17f
      author: Singh, Rakesh
       title: An urgent call for measures to fight against increasing suicides during COVID-19 pandemic in Nepal
        date: 2020-06-20
       words: 1669
      flesch: 35
     summary: However, the indicators of mental health services are not optimal in Nepal with: services being concentrated in the big cities, with 0.22 psychiatrists and 0.06 psychologists per a population of 100000, 1.5 beds per a population of 100000 for mental health patients, and less than 1% of its total healthcare budget on mental health (Uprety and Lamichhane, 2016) . In conclusion, the issue of mental health during COVID-19 pandemic has come to the forefront in Nepal with extremely concerning impact which includes increased suicidal deaths and suicidal ideation.
    keywords: covid-19; health; nepal; suicide
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        item: #6554 of 7819
          id: cord-340114-ycgc6yyc
      author: Rajagopal, Kalirajan
       title: Identification of some novel oxazine substituted 9-anilinoacridines as SARS-CoV-2 inhibitors for COVID-19 by molecular docking, free energy calculation and molecular dynamics studies
        date: 2020-07-28
       words: 3680
      flesch: 39
     summary: Many of the cases affected by COVID 19 are found to be asymptomatic (Gu et al., 2020; Holshue et al., 2020; Lu et al., 2020; To et al., 2020) , it is worthy of consideration, the detail current evidence and understanding of the transmission of SARS-CoV, MERS-CoV and SARS-CoV-2 and discuss pathogen inactivation methods on CoVs is very important (Chang et al., 2020; Huang & Herrmann, 2020; Zhang et al., 2020; Zhou, Yang, et al., 2020) . As a part of our ongoing research on searching the potent biological molecules against various diseases by in silico and wet laboratory methods (Kalirajan et al., 2011; Kalirajan, Kulshrestha, et al., 2012; Kalirajan, Mohammed Rafick, et al., 2012; Kalirajan et al., 2013; Kalirajan, Kulshrestha, et al., 2018; Kalirajan, Mohammed Rafick, et al., 2018; Kalirajan, Gaurav, et al., 2019; , we have designed and evaluated various heterocyclic compounds for their biological activities.
    keywords: binding; compounds; covid-19; docking; et al; ligand; module; novel
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        item: #6555 of 7819
          id: cord-340119-af8i359n
      author: Wang, Shi-xin
       title: Diagnosis and treatment of novel coronavirus pneumonia based on the theory of traditional Chinese medicine
        date: 2020-04-15
       words: 5329
      flesch: 45
     summary: Epub ahead of print Clinical characteristics of novel coronavirus disease 2019 in China Coronavirus: UK screens direct flights from Wuhan after US case First case of 2019 novel coronavirus in the United States Identification of a novel coronavirus causing severe pneumonia in human: a descriptive study Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study A textual research on the origin of the disease in the theory of pathogeny and syndromes. Notice on issuing the prevention and treatment plan of traditional Chinese medicine for pneumonia infected by novel coronavirus in Gansu Province (trial second edition) Traditional Chinese medicine treatment of pneumonia infected by novel coronavirus in Shaanxi Province Henan Province released a traditional Chinese medicine plan for the prevention of pneumonia caused by novel coronavirus Hebei Provincial Health Commission.
    keywords: blood; chinese; coronavirus; dampness; disease; medicine; novel; pneumonia; tcm; treatment
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        item: #6556 of 7819
          id: cord-340121-ytw82yyp
      author: Sahin, Dilek
       title: An effective protective equipment to use in the vaginal delivery of the pregnant women with suspected/diagnosed COVID-19: Delivery Table Shield
        date: 2020-06-15
       words: 514
      flesch: 40
     summary: 13.5% of asymptomatic pregnant women who applied for delivery were found to be positive for COVID-19 in a study 4 . The photographs which were taken in our simulation center show the application of delivery table shield (Image 1).
    keywords: delivery; table
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        item: #6557 of 7819
          id: cord-340137-2ipkxn9p
      author: Naguib, Mahmoud M
       title: Towards pandemic preparedness beyond COVID-19
        date: 2020-07-16
       words: 949
      flesch: 46
     summary: Hence, when such activities are reduced, the risk of new emerging zoonotic disease outbreaks with potential for global spread is greatly increased. Although we are now focused on COVID-19, it is crucial not to forget about other zoonotic pandemic threats.
    keywords: covid-19; health; pandemic
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        item: #6558 of 7819
          id: cord-340138-u8hxyfml
      author: Seneviratne, Chaminda Jayampath
       title: The Role of Dentists in COVID-19 Is Beyond Dentistry: Voluntary Medical Engagements and Future Preparedness
        date: 2020-10-06
       words: 3864
      flesch: 42
     summary: Dental practice will be considerably changed in the post-COVID-19 era. Hence, the contribution of dentists beyond dental practice in this pandemic situation will be appreciated by future generations.
    keywords: coronavirus; covid-19; dental; dentists; health; pandemic; sars; singapore; volunteers
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        item: #6559 of 7819
          id: cord-340145-nx746m76
      author: Trisolino, Giovanni
       title: Recommendations from the Italian Society of Pediatric Orthopaedics and Traumatology for the management of pediatric orthopaedic patients during the COVID19 pandemic and post-pandemic period in Italy
        date: 2020-10-08
       words: 2615
      flesch: 35
     summary: key: cord-340145-nx746m76 authors: Trisolino, Giovanni; Origo, Carlo Enrico; De Sanctis, Nando; Dibello, Daniela; Farsetti, Pasquale; Gigante, Cosimo; Guida, Pasquale; Marengo, Lorenza; Panuccio, Elena; Toniolo, Renato Maria; Verdoni, Fabio; Memeo, Antonio title: Recommendations from the Italian Society of Pediatric Orthopaedics and Traumatology for the management of pediatric orthopaedic patients during the COVID19 pandemic and post-pandemic period in Italy date: 2020-10-08 journal: The recommendations listed in this document have the following aims: 1. provide essential care to pediatric patients needing orthopaedic treatments during the COVID-19 pandemic and early post-peak period; 2. ensure safety of children and caregivers in case of hospital admission; 3. ensure safety of medical staffs; 4. limit the spread of outbreak.
    keywords: care; children; covid-19; italy; pandemic; period; priority
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        item: #6560 of 7819
          id: cord-340155-jdddm2rz
      author: Neves, Sara E.
       title: Role of Ultrasound Guided Evaluation of Dyspnea in Coronavirus Disease 2019 Pandemic
        date: 2020-07-07
       words: 2024
      flesch: 49
     summary: 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 that lung ultrasound has high sensitivity for diagnosing pneumothorax. 5 We suggest that in addition to the utilization of ultrasound for central line placement, standard use of lung ultrasound immediately post-procedure to confirm the absence of pneumothorax.
    keywords: covid-19; lung; patients; ultrasound
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        item: #6561 of 7819
          id: cord-340163-ex03l0pc
      author: Hu, Tingting
       title: A comparison of COVID-19, SARS and MERS
        date: 2020-08-19
       words: 7925
      flesch: 43
     summary: From SARS to MERS: evidence and speculation Rigidity of the outer shell predicted by a protein intrinsic disorder model sheds light on the COVID-19 (Wuhan-2019-nCoV) infectivity Nucleic acid detection with CRISPR-Cas13a/C2c2 Severe acute respiratory syndrome: global initiatives for disease diagnosis Multiple organ infection and the pathogenesis of SARS Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus: a first step in understanding SARS pathogenesis Chronic kidney disease is associated with severe coronavirus disease 2019 (COVID-19) infection First case of 2019 novel coronavirus in the United States Development and evaluation of a novel loop-mediated isothermal amplification method for rapid detection of severe acute respiratory syndrome coronavirus Clinical features of patients infected with 2019 novel coronavirus in Wuhan Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations Neurologic manifestations of hospitalized patients with coronavirus disease Screening for Middle East respiratory syndrome coronavirus infection in hospital patients and their healthcare worker and family contacts: a prospective descriptive study B38-CAP is a bacteria-derived ACE2-like enzyme that suppresses hypertension and cardiac dysfunction Emerging infections-implications for dental care Quantitative analysis and prognostic implication of SARS coronavirus RNA in the plasma and serum of patients with severe acute respiratory syndrome Lung pathology of fatal severe acute respiratory syndrome Viral load kinetics of MERS coronavirus infection Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study SARS: radiological features Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China Emerging respiratory infections threatening public health in the Asia-Pacific region: a position paper of the Asian Pacific society of respirology Radiologic pattern of disease in patients with severe acute respiratory syndrome: the Toronto experience Coronavirus infections-more than just the common cold Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study Coronaviruses post-SARS: update on replication and pathogenesis Recent trends in soft-tissue infection imaging Pulmonary embolism in patients with COVID-19: awareness of an increased prevalence Early diagnosis of SARS coronavirus infection by real time RT-PCR Identification of severe acute respiratory syndrome in Canada Cell-based therapy to reduce mortality from COVID-19: systematic review and meta-analysis of human studies on acute respiratory distress syndrome Liver-targeted angiotensin converting enzyme 2 therapy inhibits chronic biliary fibrosis in multiple drug-resistant gene 2-knockout mice Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York city area Characterization of a novel coronavirus associated with severe acute respiratory syndrome The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak Ang II (Angiotensin II) conversion to angiotensin-(1-7) in the circulation is POP (Prolyloligopeptidase)-dependent and ACE2 (Angiotensin-converting enzyme 2)-independent Characteristics and diagnosis rate of 5630 subjects receiving SARS-CoV-2 nucleic acid tests from Wuhan SARS-Coronavirus Open Reading Frame-8b triggers intracellular stress pathways and activates NLRP3 inflammasomes Development of fluorescent reverse transcription loop-mediated isothermal amplification (RT-LAMP) using quenching probes for the detection of the Middle East respiratory syndrome coronavirus ACE inhibition, ACE2 and angiotensin-(1-7) axis in kidney and cardiac inflammation and fibrosis ACE2 and ACE in acute and chronic rejection after human heart transplantation SARS: systematic review of treatment effects Human monoclonal antibody as prophylaxis for SARS coronavirus infection in ferrets Knowledge synthesis of 100 million biomedical documents augments the deep expression profiling of coronavirus receptors Value of autopsy emphasized in the case report of a single patient with Middle East respiratory syndrome Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Rapid and sensitive detection of severe acute respiratory syndrome coronavirus by rolling circle amplification Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4 Plain radiograph and CT features of 112 patients with SARS in acute stage World Health Organization (WHO). The fibrosis and consolidation in the lungs of SARS patients are more serious than the lesions caused by COVID-19, which indicates that the chest lesions are not primarily serous inflammation; instead, the exudative reaction of SARS is less than that of COVID-19.
    keywords: ace2; cells; coronavirus; cov; cov-2; covid-19; cxr; disease; et al; findings; lung; mers; patients; pneumonia; sars; studies; syndrome
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        item: #6562 of 7819
          id: cord-340164-vzdyy656
      author: Karimi, Zohreh
       title: The Lived Experience of Nurses Caring for Patients with COVID-19 in Iran: A Phenomenological Study
        date: 2020-08-20
       words: 3685
      flesch: 51
     summary: In addition to all the hardships and difficulties caused by heightened pressure in COVID-19 care centres, the fear of dying has become a challenge distracting nurses from genuine patient care; nurses have experienced being consumed by imagining the loss of life or the expectation of death causing them to distance themselves from care. Nurses need more support in the setting of COVID-19 care because nursing care practices are at serious risk.
    keywords: care; coronavirus; covid-19; nurses; participants; patients; study
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        item: #6563 of 7819
          id: cord-340168-ff6z1tpx
      author: Armitage, Richard
       title: COVID-19: Compounding the health-related harms of human trafficking
        date: 2020-06-05
       words: 529
      flesch: 19
     summary: Prevalence and risk of violence and the physical, mental, and sexual health problems associated with human trafficking: systematic review COVID-19 crisis putting human trafficking victims at risk of further exploitation, experts warn The Disease Outbreak-Human Trafficking Connection: A Missed Opportunity Access to, and experiences of, healthcare services by trafficked people: findings from a mixed-methods study in England Health of men, women, and children in posttrafficking services in Cambodia, Thailand, and Vietnam: an observational crosssectional study. key: cord-340168-ff6z1tpx authors: Armitage, Richard; Nellums, Laura B title: COVID-19: Compounding the health-related harms of human trafficking date: 2020-06-05 journal: EClinicalMedicine DOI: 10.1016/j.eclinm.2020.100409 sha: doc_id: 340168 cord_uid: ff6z1tpx nan Those affected by human trafficking are exposed to multiple severe health risks, including physical, sexual, and psychological violence, occupational hazards, and deprivation, and usually require urgent medical care to address the physical and psychological consequences of extreme exploitation [1] .
    keywords: health; trafficking
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        item: #6564 of 7819
          id: cord-340186-nc5uv2va
      author: Caligiuri, Paula
       title: International HRM insights for navigating the COVID-19 pandemic: Implications for future research and practice
        date: 2020-06-02
       words: 10286
      flesch: 34
     summary: The stress caused by the demands of virtual global work is real; many employees are experiencing long work hours to accommodate time zones and performance challenges in less than ideal remote working conditions. Applying the insights from IHRM to the pandemic situation, managers should give priority to protecting and managing employee health and safety now and in the future.
    keywords: context; covid-19; crisis; employees; future; global; health; ihrm; international; management; managers; mne; pandemic; research; talent; uncertainty; work; working
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        item: #6565 of 7819
          id: cord-340204-3gm58qza
      author: Mahmoodpoor, Ata
       title: Management of Critically Ill Patients with COVID-19: What We Learned and What We Do
        date: 2020-06-10
       words: 1706
      flesch: 43
     summary: Almost five percent of COVID-19 patients require intensive care medicine admission, and most of them are complicated with acute respiratory distress syndrome (ARDS) There are some nonspecific therapeutic agents for COVID-19 patients, but the antiviral efficacy of these drugs is not yet known (2) .
    keywords: care; covid-19; management; patients; treatment
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        item: #6566 of 7819
          id: cord-340232-cadu5ah8
      author: Aliter, Kholoud F.
       title: Thrombin Inhibition by Argatroban: Potential Therapeutic Benefits in COVID-19
        date: 2020-09-01
       words: 5326
      flesch: 31
     summary: These effects provide a strong rationale for the use of thrombin inhibitors in treating COVID-19 patients. In this review, we describe the clinical features of COVID-19, the thrombin’s roles in various pathologies, and the potential of argatroban in COVID-19 patients.
    keywords: activation; argatroban; cells; coagulation; covid-19; drug; expression; factor; inflammation; patients; potential; thrombin; treatment; virus
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        item: #6567 of 7819
          id: cord-340274-ke94njve
      author: Nayak, Saurabh
       title: Corticosteroids and COVID-19: What Could Be the Best Bet in Treating Active Glomerular Diseases in Patients With Concomitant Early COVID-19?
        date: 2020-09-28
       words: 199
      flesch: 40
     summary: High-dose but Not Low-dose Corticosteroids Potentially Delay Viral Shedding of Patients With COVID-19 Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan Dexamethasone in Hospitalized Patients with Covid-19 -Preliminary Report Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study A Narrative Systematic Review of the Clinical Utility of Cycle Threshold Values in the Context of COVID-19 COVID-19: implications for immunosuppression in kidney disease and transplantation key: cord-340274-ke94njve authors: Nayak, Saurabh; Bharati, Joyita title: Corticosteroids and COVID-19: What Could Be the Best Bet in Treating Active Glomerular Diseases in Patients With Concomitant Early COVID-19? date: 2020-09-28 journal: Am J Kidney Dis DOI: 10.1053/j.ajkd.2020.09.006 sha: doc_id: 340274 cord_uid: ke94njve nan antiviral agent could be done.
    keywords: covid-19
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        item: #6568 of 7819
          id: cord-340283-5w444i1g
      author: Das, Anupam
       title: Erythematous‐oedematous type of chilblain‐like lesions and COVID‐19 : an Indian perspective
        date: 2020-06-27
       words: 460
      flesch: 36
     summary: 8 Cutaneous manifestations in COVID-19: a first perspective A dermatologic manifestation of COVID-19: transient livedo reticularis COVID-19 can present with a rash and be mistaken for dengue Cutaneous manifestations in COVID-19: a new contribution Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases Chilblain-like lesions during COVID-19 epidemic: a preliminary study on 63 patients Chilblain-like lesions on feet and hands during the COVID-19 Pandemic Absence of Skin of Colour Images in Publications of COVID-19 Skin Manifestations In another series published from Italy, authors noticed an outbreak of chilblain-like lesions in Italy contemporary to COVID-19 epidemic, who reported two varieties of lesions, namely erythematous-oedematous type and blistering type.
    keywords: covid-19; patients
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        item: #6569 of 7819
          id: cord-340284-xo7q4dqr
      author: Pappa, Sofia
       title: Prevalence of depression, anxiety, and insomnia among healthcare workers during the COVID-19 pandemic: A systematic review and meta-analysis
        date: 2020-05-08
       words: 2969
      flesch: 38
     summary: Furthermore, low risk of bias studies (n=9) revealed a total pooled anxiety prevalence of 24·05% (95% CI 16·84-32·07, I 2 =99%). Studies scoring ≥3 points were regarded as low risk of bias, compared to the studies assessed with <3 points that were regarded as high risk of bias.
    keywords: analysis; anxiety; covid-19; depression; health; prevalence; studies
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        item: #6570 of 7819
          id: cord-340285-mq9x12nw
      author: Blagosklonny, Mikhail V.
       title: From causes of aging to death from COVID-19
        date: 2020-06-12
       words: 5970
      flesch: 39
     summary: This review is intended for a professional audience, to stimulate new ideas and to aid the global efforts to develop effective treatments for COVID-19 disease. Geroscience: linking aging to chronic disease Rejuvenating immunity: anti-aging drug today eight years later mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells Rapamycin-induced enhancement of vaccine efficacy in mice Immunostimulatory activity of lifespan-extending agents mTOR regulates memory CD8 t-cell differentiation Paradoxical aspects of rapamycin immunobiology in transplantation Sirolimus enhances the magnitude and quality of viralspecific CD8+ t-cell responses to vaccinia virus vaccination in rhesus macaques Chronic mTOR inhibition in mice with rapamycin alters T, B, myeloid, and innate lymphoid cells and gut flora and prolongs life of immune-deficient mice mTOR inhibition improves immune function in the elderly TORC1 inhibition enhances immune function and reduces infections in the elderly Cutting edge: rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses Aging, obesity, and inflammatory age-related diseases Immunosenescence in aging: between immune cells depletion and cytokines up-regulation mTORC1 signaling governs hematopoietic stem cell quiescence Aging, stem cells, and mammalian target of rapamycin: a prospect of pharmacologic rejuvenation of aging stem cells Geroconversion of aged muscle stem cells under regenerative pressure Microenvironmental contributions to hematopoietic stem cell aging Long-term adaptation to hypoxia preserves hematopoietic stem cell function Regulation of the HIF-1alpha level is essential for hematopoietic stem cells Hypoxia suppresses conversion from proliferative arrest to cellular senescence Rapamycin enhances long-term hematopoietic reconstitution of ex vivo expanded mouse hematopoietic stem cells by inhibiting senescence Rapamycin is highly effective in murine models of immune-mediated bone marrow failure Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway.
    keywords: age; aging; cells; covid-19; diabetes; diseases; growth; hyper; immune; mortality; mtor; patients; rapamycin; senescence
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        item: #6571 of 7819
          id: cord-340298-0l4pec0z
      author: Terriau, A.
       title: Impact of virus testing on COVID-19 case fatality rate: estimate using a fixed-effects model
        date: 2020-05-01
       words: 3971
      flesch: 50
     summary: key: cord-340298-0l4pec0z authors: Terriau, A.; Albertini, J.; Poirier, A.; LE BASTARD, Q. title: Impact of virus testing on COVID-19 case fatality rate: estimate using a fixed-effects model date: 2020-05-01 journal: nan DOI: 10.1101/2020.04.26.20080531 sha: doc_id: 340298 cord_uid: 0l4pec0z Background In response to the SARS-CoV2 pandemic, governments have adopted a variety of public health measures. Our estimates reveal that a 1 pp increase in the tests/hospitalizations ratio leads to a statistically significant drop of case mortality rate by 0.001 pp.
    keywords: covid-19; department; health; license; preprint; rate; testing; tests
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        item: #6572 of 7819
          id: cord-340303-1xd5tntx
      author: Durmuş, Veli
       title: Tendencias epidémicas en los diez principales países con más casos de COVID-19 en comparación con Turquía
        date: 2020-09-14
       words: 3793
      flesch: 58
     summary: However, during the first period, especially on January 2020, the cumulative number of COVID-19 cases globally followed a sharp increase, likely as a result of the outbreak management policy of the government. The outbreak rapidly spread to more than 200 countries and led to millions of confirmed cases as well as thousands of deaths worldwide.
    keywords: 2020; cases; countries; covid-19; rate
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        item: #6573 of 7819
          id: cord-340305-jtvn9tlm
      author: Cimolai, Nevio
       title: A Minimalist Strategy Towards Temporarily Defining Protection for COVID-19
        date: 2020-09-19
       words: 5117
      flesch: 33
     summary: Glob Health Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice Therapy with a severe acute respiratory syndrome-associated coronavirus-neutralizing human monoclonal antibody reduces disease severity and viral burden in golden Syrian hamsters Comparison of immunoglobulin G responses to the spike and nucleocapsid proteins of severe acute respiratory syndrome (SARS) coronavirus in patients with SARS Potently neutralizing and protective human antibodies against SARS-CoV-2 Potent neutralizing antibodies against SARS-CoV-2 identified by highthroughput single-cell sequencing of convalescent patients' B cells Shahverdi S Clinical efficacy and convalescent plasma for treatment of COVID-19 infections: results of a multicenter clinical study Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development A SARS-CoV-2 neutralizing antibody protects from lung pathology in COVID-19 hamster model Passive immunization against transmissible gastroenteritis virus in piglets by ingestion of milk of sows inoculated with attenuated virus Effect of specific humoral immunity and some nonspecific factors on resistance of volunteers to respiratory coronavirus infection Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in rhesus macaques Protective effect of immunoglobulins in serum and milk of sows exposed to transmissible gastroenteritis virus Neutralization of a transmissible gastroenteritis virus of swine by colostral antibodies elicited by intestine and cell culture-propagated virus Intestinal, pulmonary, and serum antibody responses of feeder pigs exposed to transmissible gastroenteritis virus by the oral and the oral-intranasal routes in inoculation Mucosal and systemic isotype-specific antibody responses and protection in conventional pigs exposed to virulent or attenuated porcine epidemic diarrhoea virus Isotype-specific antibody responses to bovine coronavirus structural proteins in serum, feces, and mucosal secretions from experimentally challengeexposed colostrum-deprived calves Primary exposure to SARS-CoV-2 protects against reinfection in Rhesus macaques Relationship among transmissible gastroenteritis virus antibody titers in serum, colostrum, and milk from vaccinated sows, and protection in their suckling pigs Passive protection of neonatal calves against bovine coronavirus-induced diarrhea by administration of egg yolk or colostrum antibody powder The time course of the immune response to experimental coronavirus infection of man Infectious Middle East Respiratory Syndrome coronavirus excretion and serotype variability based on live virus isolates from patients in Saudi Arabia Viral shedding and antibody response in 37 patients with Middle East Respiratory Syndrome coronavirus infection Sensitive and specific detection of low-level antibody responses in mild Middle East Respiratory Syndrome coronavirus infections MERS-CoV antibody responses 1 year after symptom onset, South Korea Persistence of antibodies against Middle East Respiratory Syndrome coronavirus High neutralizing antibody titer in intensive care unit patients with COVID-19 Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2 Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections Evaluating the association of clinical characteristics with neutralizing antibody levels in patients who have recovered from mild COVID-19 in Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications on COVID-19 immunity Dynamics and significance of the antibody response to SARS-CoV-2 infection Humoral and cellular and circulating follicular helper T cell responses in recovered patients with COVID-19 Antibody profiles according to mild or severe SARS-CoV-2 infection Human-IgGneutralizing monoclonal antibodies block the SARS-CoV-2 infection Rapid generation of neutralizing antibody responses in COVID-19 patients Severe acute respiratory syndrome coronavirus 2-specific antibody responses in coronavirus disease patients Expansion of SARS-CoV-2-specific antibody-secreting cells and generation of neutralizing antibodies in hospitalized COVID-19 patients Antibody response to SARS-CoV-2 are distinct in children with MIS-C compared to adults with COVID-19 Pediatric SARS-CoV-2: clinical presentation, infectivity, and immune responses SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19 SARS-CoV-2 serology and virology trends in donors and recipients of convalescent plasma Viral dynamics and immune correlates of COVID-19 disease severity Anti SARS-CoV-2 antibodies monitoring in a group of residents in a long term care facility during COVID-19 pandemic peak Sex differences in immune responses that underlie COVID-19 disease outcomes Development and characterization of neutralizing monoclonal antibody to the SARS-coronavirus The behavior of recent isolates of human respiratory coronavirus in vitro and in volunteers: evidence of heterogeneity among 229E-related strains Sequential emergence and wide spread of neutralization escape Middle East Respiratory Syndrome coronavirus mutants Increased antibody affinity confers broad in vitro protection against escape mutants of severe acute respiratory syndrome coronavirus COVID-19 re-infection by a phylogenetically distinct SARScoronavirus-2 strain confirmed by whole genome sequencing Adaptive immune responses to SARS-CoV-2 infection in severe versus mild individuals Functional SARS-CoV-2-specific immune m e m Does neutralization antibody ensure protection?
    keywords: antibodies; antibody; assay; coronavirus; cov-2; covid-19; infection; neutralization; patients; protection; responses; sars
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        item: #6574 of 7819
          id: cord-340323-xz6v95yy
      author: Urbach, Horst
       title: Notfällige Neurointerventionen, Covid-19 und Thorax-CT: SOP und Literaturübersicht
        date: 2020-05-07
       words: 1439
      flesch: 41
     summary: To analyze standard operating procedures (SOP) of acute stroke imaging and interventions during COVID-19 pandemic with special emphasis on chest CT within a multimodal stroke protocol. Answers were received from 25 units: eleven of them acquire chest CT, three in any patient and eight, when COVID-19 is suspected due to body temperature increase, patient’s history or when the latter cannot be sufficiently obtained.
    keywords: chest; coronavirus; covid-19; das; der; die; ein; und; werden
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        item: #6575 of 7819
          id: cord-340354-j3xsp2po
      author: Noll, N. B.
       title: COVID-19 Scenarios: an interactive tool to explore the spread and associated morbidity and mortality of SARS-CoV-2
        date: 2020-05-07
       words: 4325
      flesch: 45
     summary: https://doi.org/10.1101/2020.05.05.20091363 doi: medRxiv preprint Figure 2 User interface for model parameters and mitigations A) An example screenshot of the UI of the web application used to vary model parameters.
    keywords: age; covid-19; data; mitigation; model; parameters; preprint; scenarios; time; tool
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        item: #6576 of 7819
          id: cord-340367-h608bj86
      author: Yarali, Neşe
       title: Hematological parameters and peripheral blood morphologic abnormalities in children with COVID‐19
        date: 2020-08-06
       words: 799
      flesch: 47
     summary: Pediatr Blood Cancer DOI: 10.1002/pbc.28596 sha: doc_id: 340367 cord_uid: h608bj86 nan To the Editor, Quantitative and qualitative changes in peripheral blood cells have been described in adults with coronavirus disease 2019 (COVID-19). [5] This retrospective study aims to define the peripheral blood alterations in children with COVID-19 and compare them with patients with similar symptoms without COVID-19.
    keywords: children; covid-19; patients
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        item: #6577 of 7819
          id: cord-340381-qfp5p6gv
      author: Faddoul, Annibal
       title: L’anesthésie au temps du COVID
        date: 2020-08-20
       words: 2367
      flesch: 50
     summary: D'autres interventions doivent faire l'objet d'un dépistage systématique préalable il s'agit de la chirurgie ORL du fait d'un risque très élevé de contamination des soignants et de la chirurgie pulmonaire qui cumule le risque de contamination élevé et La principale préoccupation tient à la permanence de la présence virale dans la population.
    keywords: dans; des; est; les; patients; que; qui; une
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        item: #6578 of 7819
          id: cord-340394-yzkl0chl
      author: Sarkis, Joseph
       title: Overcoming the Arrogance of Ignorance: Supply-Chain Lessons from COVID-19 for Climate Shocks
        date: 2020-07-24
       words: 2395
      flesch: 45
     summary: It is redolent of our experience with the COVID-19 crisis and of our approach-so far-to climate shocks. Climate shocks are not black swans either.
    keywords: chains; climate; covid-19; ignorance; shocks; supply
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        item: #6579 of 7819
          id: cord-340397-b43zgxgv
      author: Buenaventura, Robert D.
       title: COVID-19 and mental health of older adults in the Philippines: a perspective from a developing country
        date: 2020-04-30
       words: 3037
      flesch: 40
     summary: In this commentary, we discuss the impact of COVID-19 on the mental health of older Filipinos, who are more vulnerable to the effects of COVID-19, and describe ways that healthcare workers can help alleviate the negative impact on their mental health to the extent possible within the limited resources available in the Philippines. Older Filipinos have a life expectancy of 71 years, which is slightly below the world average of 72 years (Philippine Statistics Authority, 2016a).
    keywords: covid-19; filipinos; health; individuals; pandemic; philippines; population
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        item: #6580 of 7819
          id: cord-340398-bph0ro5v
      author: Yan, Xisheng
       title: Neutrophil to lymphocyte ratio as prognostic and predictive factor in patients with coronavirus disease 2019: A retrospective cross‐sectional study
        date: 2020-06-09
       words: 1921
      flesch: 38
     summary: The role of neutrophil to lymphocyte count ratio in the differential diagnosis of pulmonary tuberculosis and bacterial community-acquired pneumonia: a cross-sectional study at Ayder and Mekelle Hospitals Neutrophil to lymphocyte ratio and cardiovascular diseases: a review The systemic inflammation-based neutrophil-lymphocyte ratio: experience in patients with cancer Neutrophil-lymphocyte ratio as a predictor of adverse outcomes of acute pancreatitis Dysregulation of immune response in patients with COVID-19 in Wuhan, China SARS immunity and vaccination Neutrophil-to-Lymphocyte Ratio Predicts Severe Illness Patients with 2019 Novel Coronavirus in the Early Stage Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study Older adults in the emergency department: a systematic review of patterns of use, adverse outcomes, and effectiveness of interventions White blood cell counts, leukocyte ratios, and eosinophils as inflammatory markers in patients with coronary artery disease Older patients in the emergency department: a review Neutrophils in development of multiple organ failure in sepsis Persistent lymphopenia after diagnosis of sepsis predicts mortality Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern Lymphocytopenia and neutrophillymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit Neutrophil-to-lymphocyte ratio, calprotectin and YKL-40 in patients with chronic obstructive pulmonary disease: correlations and 5-year mortality-a cohort study Neutrophil to lymphocyte ratio as prognostic and predictive factor in patients with coronavirus disease 2019: key: cord-340398-bph0ro5v authors: Yan, Xisheng; Li, Fen; Wang, Xiao; Yan, Jie; Zhu, Fen; Tang, Shifan; Deng, Yingzhong; Wang, Hua; Chen, Rui; Yu, Zhili; Li, Yaping; Shang, Jingzhou; Zeng, Lingjun; Zhao, Jie; Guan, Chaokun; Liu, Qiaomei; Chen, Haifeng; Gong, Wei; Huang, Xin; Zhang, Yu‐Jiao; Liu, Jianguang; Dong, Xiaoyan; Zheng, Wen; Nie, Shaoping; Li, Dongsheng title: Neutrophil to lymphocyte ratio as prognostic and predictive factor in patients with coronavirus disease 2019:
    keywords: lymphocyte; mortality; neutrophil; nlr; patients; ratio
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        item: #6581 of 7819
          id: cord-340415-6fte7krp
      author: Thevarajan, Irani
       title: Clinical presentation and management of COVID‐19
        date: 2020-07-17
       words: 4292
      flesch: 36
     summary: The majority of patients presenting with coronavirus disease 2019 (COVID‐19) experience a mild illness that can usually be managed in the community. Patients require careful monitoring and early referral to hospital if any signs of clinical deterioration occur.
    keywords: care; covid-19; days; disease; hospital; infection; management; patients; sars; treatment
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        item: #6582 of 7819
          id: cord-340433-h86cufyp
      author: Sahu, Bikash R
       title: C-reactive protein: a promising biomarker for poor prognosis in COVID-19 infection
        date: 2020-06-05
       words: 1368
      flesch: 34
     summary: Based on these observations, various studies were carried out in COVID-19 patients hypothesizing CRP as one of the possible biomolecules linked with the death of the infected patients. retrospective study Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 (COVID-19) in Wuhan, China: a retrospective study COVID-19 in persons with haematological cancers Clinical Characteristics of Deceased Patients Infected with SARS-CoV-2 in Prognostic value of C-reactive protein in patients with COVID-19 Correction to: Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan Clinical features of 95 sequential hospitalised patients with novel coronavirus 2019 disease (COVID-19), the first UK cohort Clinicolaboratory study of 25 fatal cases of COVID-19 in Wuhan Clinical and laboratory predictors of in-hospital mortality in patients with COVID-19: a cohort study in Wuhan, China Coronavirus disease 2019 in elderly patients: Characteristics and prognostic factors based on 4-week follow-up Clinical Course and Outcomes of 344 Intensive Care Patients with COVID-19 Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Clinical characteristics and outcomes of patients with severe covid-19 with diabetes Characteristics, treatment, outcomes and cause of death of invasively ventilated patients with COVID-19 of The clinical data from 19 critically ill patients with coronavirus disease 2019: a single-centered, retrospective, observational study Predictive factors for disease progression in hospitalized patients with coronavirus disease 2019 in Wuhan CRP level is elevated in COVID-19 patients.
    keywords: analysis; covid-19; crp; patients
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        item: #6583 of 7819
          id: cord-340436-qiyoamek
      author: Varshney, Anubodh S.
       title: Characteristics of Clinical Trials Evaluating Cardiovascular Therapies for Coronavirus Disease 2019 Registered on ClinicalTrials.gov: A Cross Sectional Analysis
        date: 2020-10-26
       words: 2678
      flesch: 30
     summary: We therefore evaluated registered clinical trials of established CV therapies related to COVID-19 using the ClinicalTrials.gov database, which was established to improve monitoring and conduct of research studies 14 . Of CV therapy studies, most were planned to be single center, enroll less than 1000 inpatients, sponsored by European or North American academic institutions, and estimated to complete after December 2020.
    keywords: clinicaltrials.gov; covid-19; patients; studies; study; therapies; trials
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        item: #6584 of 7819
          id: cord-340464-axb6resr
      author: Vijayasekaran, D.
       title: COVID-19 Pandemic: The Way Forward – Correspondence
        date: 2020-11-04
       words: 437
      flesch: 34
     summary: key: cord-340464-axb6resr authors: Vijayasekaran, D.; Kalpana, S. title: COVID-19 Pandemic: The Way Forward – Correspondence date: 2020-11-04 journal: Indian J Pediatr DOI: 10.1007/s12098-020-03553-z sha: doc_id: 340464 cord_uid: axb6resr nan To the Editor: The editorial on COVID-19 Pandemic: The Way Forward by Rakesh Lodha & S K Kabra covered many important precautions to be observed both in overcrowded hospitals and private clinics in the context of present crisis [1] . Considering the uncertainty of many aspects related to COVID-19, as the authors reiterated, physicians should adapt themselves to telemedicine.
    keywords: covid-19; pandemic
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        item: #6585 of 7819
          id: cord-340468-3s3dv88w
      author: Plumereau, Cécile
       title: Effect of the COVID-19 pandemic on acute stroke reperfusion therapy: data from the Lyon Stroke Center Network
        date: 2020-09-09
       words: 2159
      flesch: 51
     summary: Emergency Department and Out-of-Hospital Emergency System (112-AREU 118) integrated response to Coronavirus Disease 2019 in a Northern Italy centre Forgotten key players in public health: news media as agents of information and persuasion during the COVID-19 pandemic Impact of the COVID-19 epidemic on stroke care and potential solutions Acute stroke management pathway during Coronavirus-19 pandemic Mechanical thrombectomy for acute ischemic stroke amid the COVID-19 outbreak: decreased activity, and increased care delays Acute stroke care is at risk in the Era of COVID-19: experience at a Comprehensive Stroke Center in Barcelona Impact of the COVID-19 outbreak on acute stroke pathways-insights from the Alsace region in France Effect of COVID-19 on emergent stroke care: a regional experience Effect of lockdown on the management of ischemic stroke: an Italian experience from a COVID hospital Acute stroke in times of the COVID-19 pandemic: a multicenter Study Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy Randomised doubleblind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II) Avoiding misdiagnosis in patients with posterior circulation ischemia: a narrative review Stroke care in Italy: an overview of strategies to manage acute stroke in COVID-19 time Conflicts of interest The authors declare that they have no conflict of interest. The effect of the COVID-19 pandemic on stroke care is still debated.
    keywords: care; covid-19; pandemic; patients; period; stroke
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        item: #6586 of 7819
          id: cord-340474-hbcu72cm
      author: Kaushik, Akanksha
       title: Urticaria in the times of COVID‐19
        date: 2020-06-12
       words: 669
      flesch: 46
     summary: On closer look, we find urticaria to be a commonly reported finding among COVID-19 patients. As per one review, 88/256 (34.3%) patients across 16 studies demonstrated skin manifestations, mostly as erythematous maculopapular rash, urticaria or vesicular rash.
    keywords: covid-19; urticaria
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        item: #6587 of 7819
          id: cord-340511-syy9okhi
      author: Dettori, Marco
       title: Air pollutants and risk of death due to COVID-19 in Italy
        date: 2020-11-11
       words: 4037
      flesch: 43
     summary: As far as the environmental pollution and both the spread of the virus in generating outbreaks and case fatality rate are concerned, this research appears to find elements to confirm the existence of a link between air pollution, this latter referred to particulate (PM 10 ) and COVID-19 mortality. In Italy, the areas most affected are found within the Po Valley, known for its high levels of air pollution, apparently sparing a large part of central Italy and most of southern Italy.
    keywords: air; covid-19; italy; mortality; pollutants; pollution; provinces; values
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        item: #6588 of 7819
          id: cord-340512-wjbh1z8y
      author: Dugas, M.
       title: COVID-19 in Children with Brain-Based Developmental Disabilities: A Rapid Review
        date: 2020-05-06
       words: 2860
      flesch: 43
     summary: Pediatric pulmonology Systematic review of COVID-19 in children show milder cases and a better prognosis than adults People Who Are at Higher Risk for Severe Illness: Center for Disease Control and Prevention COVID-19 response: Considerations for Children and Adults with Disabilities Prevalence of symptoms and comorbid conditions in novel coronavirus (COVID-19)-infected adult and paediatric patients: a systematic review and metaanalysis of first three-month data of the outbreak CRD42020176341 The authors would like to thank the panel of knowledge users for their support throughout this review. key: cord-340512-wjbh1z8y authors: Dugas, M.; Carnovale, V.; Poirier, A.-A.; Mailot, B.; Skidmore, B.; Faust, L.; Costello, C.; Thomson, D.; Majnemer, A.; Goldowitz, D.; Miller, S.; LeBlanc, A. title: COVID-19 in Children with Brain-Based Developmental Disabilities: A Rapid Review date: 2020-05-06 journal: nan DOI: 10.1101/2020.05.01.20088021 sha: doc_id: 340512 cord_uid: wjbh1z8y Background.
    keywords: brain; children; covid-19; disabilities; preprint; review
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        item: #6589 of 7819
          id: cord-340535-78bpvtuf
      author: Elbay, Rümeysa Yeni
       title: Depression, Anxiety, Stress Levels of Physicians and Associated Factors In Covid-19 Pandemics
        date: 2020-05-27
       words: 2430
      flesch: 45
     summary: An online survey is conducted to asses psychological responses of healthcare workers and related factors during Covid-19 outbreak. Therefore, there is an urgent need for more systematic research to understand the psychological effects of Covid-19 outbreak on healthcare workers and related risk and protective factors.
    keywords: anxiety; covid-19; outbreak; scores; stress
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        item: #6590 of 7819
          id: cord-340536-azlajqbe
      author: Bartolo, Michelangelo
       title: Urgent Measures for the Containment of the Coronavirus (Covid-19) Epidemic in the Neurorehabilitation/Rehabilitation Departments in the Phase of Maximum Expansion of the Epidemic
        date: 2020-04-30
       words: 2658
      flesch: 30
     summary: Furthermore, in some areas due to the lack of beds, rehabilitation facilities are now being occupied with other patients, with consequent difficulty in hospitalizing patients, for example, discharged from stroke units. The following indications are suggested in order to make the reorganization of rehabilitation activities homogeneous, whether they are carried out in hospitalization or outpatient settings or at home, with the main aim of limiting patient flows within the facilities and maintaining staff safety.
    keywords: activities; care; cases; covid-19; epidemic; health; patients; rehabilitation
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        item: #6591 of 7819
          id: cord-340537-pdvpmydk
      author: Bañon-Gonzalez, Rafael
       title: Autopsies of suspected SARS-CoV-2 cases
        date: 2020-07-15
       words: 3686
      flesch: 46
     summary: Although there are analytical hypercoagulability markers in the physiopathology of COVID-19 disease, with raised D-dimer and indications of disseminated intravascular coagulation, only Yao et al. describe thrombi in the small vessels of several organs (thrombi in glomerular capillaries are visible in a photograph in their original publication in Chinese), 34 all other works limit thrombotic microangiopathy to the lungs. In connection with COVID-19 disease, in spite of its high rate of mortality there have been few studies.
    keywords: autopsies; cases; coronavirus; cov-2; covid-19; disease; infection; sars; studies; virus
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        item: #6592 of 7819
          id: cord-340538-vjw7d5ju
      author: Brown, Joshua D.
       title: Survey reported medication changes among older adults during the SARS-CoV-2 (COVID-19) pandemic
        date: 2020-11-12
       words: 2092
      flesch: 44
     summary: key: cord-340538-vjw7d5ju authors: Brown, Joshua D.; Vouri, Scott M.; Manini, Todd M. title: Survey reported medication changes among older adults during the SARS-CoV-2 (COVID-19) pandemic date: 2020-11-12 journal: Res Social Adm Pharm DOI: 10.1016/j.sapharm.2020.11.005 sha: doc_id: 340538 cord_uid: vjw7d5ju BACKGROUND: Speculation on benefits and harms of prescription, over-the-counter and complementary medications has been widespread during the SARS-CoV-2 (or COVID-19) pandemic. Questions related to medication changes included: “Have you started any medication due to COVID-19”, “Have you stopped any medication due to COVID-19” and “Have you had issues getting your prescription medications.”
    keywords: changes; community; covid-19; medications; survey
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        item: #6593 of 7819
          id: cord-340553-vofar32b
      author: Atique, Suleman
       title: A nursing informatics response to COVID‐19: perspectives from five regions of the world
        date: 2020-05-18
       words: 3698
      flesch: 39
     summary: Nursing informaticians who use information technology to enhance nursing education, clinical practice and policy are collaborating with colleagues and contributing to and leading research and digital health initiatives in the face of COVID-19. Existing digital health services have also been expanded.
    keywords: coronavirus; covid-19; disease; government; health; healthcare; informaticians; nursing; public; response; world
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        item: #6594 of 7819
          id: cord-340564-3fu914lk
      author: Cohen, Joseph Paul
       title: Predicting COVID-19 Pneumonia Severity on Chest X-ray With Deep Learning
        date: 2020-07-28
       words: 3259
      flesch: 49
     summary: In the case of building a predictive tool for COVID-19 CXR images, the lack of a public database made it difficult to conduct large-scale robust evaluations. A neural network model that was pre-trained on large (non-COVID-19) chest X-ray datasets is used to construct features for COVID-19 images which are predictive for our task.
    keywords: chest; covid-19; dataset; images; lung; model; opacity; prediction
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        item: #6595 of 7819
          id: cord-340573-6uz6uw7i
      author: Gleeson, Sarah
       title: Lesson for the clinical nephrologist: Kidney transplant, COVID-19 and pregnancy
        date: 2020-11-12
       words: 1501
      flesch: 46
     summary: This patient's pregnancy was complicated both by her kidney transplant and maintenance immunosuppression and then by COVID-19 infection requiring admission and supplemental oxygen. The combination of COVID-19 infection in a pregnant kidney transplant recipient has not previously been reported.
    keywords: covid-19; infection; kidney; pregnancy
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        item: #6596 of 7819
          id: cord-340578-5vyv9swb
      author: Pedraja, J.
       title: Role of 3D printing in the protection of surgical and critical care professionals in the COVID-19 pandemic
        date: 2020-10-09
       words: 3361
      flesch: 38
     summary: Advances in 3D printing technology and the development of strong, flexible, biocompatible and sterilisable polymers can help hospitals overcome shortages of some critical supplies. Int J Oral Maxillofac Surg Emergency opensource three-dimensional printable ventilator circuit splitter and flow regulator during the COVID-19 pandemic Applications of 3D printing technology to address COVID-19 related supply shortages 3D-printable PP/SEBS thermoplastic elastomeric blends: preparation and properties Novel biomaterials used in medical 3D printing techniques We would like to thank all the health professionals who faced the challenges arising from the COVID-19 outbreak in Cantabria, the heads of clinical services, care units and organisations in the autonomous community for reorganizing the resources available to address the pandemic, and both individuals and companies for their disinterested collaboration.
    keywords: covid-19; equipment; face; hospital; pandemic; patients; printing; use
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        item: #6597 of 7819
          id: cord-340583-kjrxrk50
      author: Castro‐Rodriguez, Jose A.
       title: Asthma and COVID‐19 in children – a systematic review and call for data
        date: 2020-06-18
       words: 3087
      flesch: 34
     summary: Summary of a Report of 72314 Cases From the Chinese Center for Disease Control and Prevention Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Distinct characteristics of COVID-19 patients with initial rRT-PCR-positive and rRT-PCRnegative results for SARS-CoV-2. However, the largest studies to date have been limited to a description of the number of cases by age group, and so it remains unclear whether childhood asthma -or other pediatric respiratory diseases-are associated with COVID-19 risk or severity.
    keywords: asthma; children; clinical; covid-19; disease; patients; risk; sars
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        item: #6598 of 7819
          id: cord-340616-5vtgd46s
      author: ÇETİN, Ceren
       title: Global surveillance, travel, and trade during a pandemic
        date: 2020-04-21
       words: 3979
      flesch: 41
     summary: Pandemic diseases may result in acute, short-term fiscal shocks and long-term damage in economic growth. As pandemic viruses emerge, countries and regions face different risks at different times.
    keywords: countries; covid-19; health; international; management; pandemic; public; risk; world
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        item: #6599 of 7819
          id: cord-340646-dj1gqzzt
      author: Molina, Gabriel A.
       title: COVID-19 in Ecuador, how the pandemic strained the surgical healthcare systems over the edge
        date: 2020-09-02
       words: 1606
      flesch: 48
     summary: Nonetheless, the complete ramifications of this disease are yet to be seen, as surgical patients require close follow up to avoid complications and to provide necessary treatment when they arise. Most of the surgical workforce was transferred and are still in COVID-19 care.
    keywords: authors; care; consent; covid-19; patients
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        item: #6600 of 7819
          id: cord-340650-mwsa326c
      author: Elangovan, E. J.
       title: Rationale and prognosis of repurposed drugs with risk stratification of patients in oxygen support in COVID-19: A systematic review and meta-analysis
        date: 2020-10-06
       words: 6406
      flesch: 47
     summary: [5.39-140.24 ]) of severe COVID-19 patients ( Figure 1 ). Vs. 37.5% STD) in viral load negativity within 72 hrs after CP transfusion in severe COVID-19 patients [44] .
    keywords: covid-19; license; medrxiv; mortality; patients; perpetuity; preprint; rate; studies; study; treatment
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        item: #6601 of 7819
          id: cord-340656-ltd6ueoi
      author: Grant, Michael C.
       title: The prevalence of symptoms in 24,410 adults infected by the novel coronavirus (SARS-CoV-2; COVID-19): A systematic review and meta-analysis of 148 studies from 9 countries
        date: 2020-06-23
       words: 3443
      flesch: 38
     summary: Analysis of clinical symptoms in adult patients Clinical and Laboratory Profiles of 75 Hospitalized Patients with Novel Coronavirus Disease Clinical features and outcomes of 197 adult discharged patients with COIVD-19 in Yichang Optimizing diagnostic strategy for novel coronavirus pneumonia The necessity to address deficiencies in current literature and potential to substantially improve the precision of estimates of symptom prevalence using both indexed and (the more voluminous and up-to-date) preprint literature from multiple geographical regions, represents the rational for this review.
    keywords: characteristics; clinical; coronavirus; covid-19; patients; prevalence; studies; symptoms
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        item: #6602 of 7819
          id: cord-340663-zylk61ll
      author: Singh, Devendra Raj
       title: The perils of COVID-19 in Nepal: Implications for population health and nutritional status
        date: 2020-06-17
       words: 1686
      flesch: 46
     summary: The major public health challenge for Nepal is the lack of access to health care against the backdrop of weak and inadequate public health infrastructure [8] . This has had a negative impact on health care, severely affecting reproductive, maternal, and child health services and those with chronic health conditions and non-communicable diseases.
    keywords: care; covid-19; food; health; nepal
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        item: #6603 of 7819
          id: cord-340687-99ad1rwq
      author: Abourida, Yassamine
       title: Management of Severe COVID-19 in Pregnancy
        date: 2020-07-27
       words: 2532
      flesch: 41
     summary: Information for healthcare professionals Analysis of vaginal delivery outcomes among pregnant women in Wuhan, China during the COVID-19 pandemic Estimation of the epidemic properties of the 2019 novel coronavirus: a mathematical modeling study The presence of SARS-CoV-2 RNA in the feces of COVID-19 patients Pneumonia in pregnancy Organisation et prise en charge de la grossesse, de l'accouchement et du post-partum durant la période de pandémie COVID-19 Systematic review of hydroxychloroquine use in pregnant patients with autoimmune diseases Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France Hydroxychloroquine and azithromycin as a treatment of COVID-19: preliminary results of an open-label non-randomized clinical trial Safety and efficacy of different anesthetic regimens for parturients with COVID-19 undergoing Cesarean delivery: a case series of 17 patients Evidence for and against vertical transmission for severe acute respiratory syndrome coronavirus 2 Unlikely SARS-CoV-2 vertical transmission from mother to child: a case report Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn Severe COVID-19 during pregnancy and possible vertical transmission Coronavirus disease 2019 (COVID-19) pandemic and pregnancy Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Perinatal transmission of COVID-19 associated SARS-CoV-2: should we worry? Coronavirus disease 2019 in pregnant women: a report based on 116 cases Two cases of coronavirus 2019-related cardiomyopathy in pregnancy Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis Placental pathology in COVID-19 positive mothers: preliminary findings Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern: the fragile balance between infections and autoimmunity Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway Regulation of ferritin genes and protein COVID-19) infection in pregnancy.
    keywords: cov-2; covid-19; delivery; infection; pregnancy; sars; transmission
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        item: #6604 of 7819
          id: cord-340710-dmow5p7k
      author: Lagana, Stephen M.
       title: Hepatic pathology in patients dying of COVID-19: a series of 40 cases including clinical, histologic, and virologic data
        date: 2020-08-13
       words: 4542
      flesch: 45
     summary: As the focus of this study is liver pathology, the lungs were considered only in the context of how the pulmonary findings may relate to liver injury. The role of immunosuppression and allograft recipient status on liver injury associated with COVID-19 will need further study.
    keywords: acute; cases; covid-19; hepatitis; injury; liver; patients; pcr; steatosis
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        item: #6605 of 7819
          id: cord-340713-v5sdowb7
      author: Bird, Jordan J.
       title: Country-level pandemic risk and preparedness classification based on COVID-19 data: A machine learning approach
        date: 2020-10-28
       words: 5672
      flesch: 49
     summary: With the previous successful experiments in mind, this argues that risk classification would be more useful when performed prior to the situation unfolding, given that country-level information is seemingly more important at this stage when compared to the current postpeak climate. The positive effects of these factors likely contribute towards the reason why country-level information was useful for risk classification earlier in the pandemic, but are less-so later on post-peak.
    keywords: attributes; classification; country; covid-19; data; learning; level; machine; models; risk; test
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        item: #6606 of 7819
          id: cord-340725-xy74wd6j
      author: Sora, Federica
       title: SARS COV 2 INFECTION IN CHRONIC MYELOGENOUS LEUKEMIA: SEVERE HEMATOLOGICAL PRESENTATION
        date: 2020-07-23
       words: 1001
      flesch: 31
     summary: COVID-19: consider cytokine storm syndromes and immunosuppression Development and validation of the HScore, a score for the diagnosis of reactive hemophagocytic syndrome Evans syndrome in a patient with COVID-19 Simultaneous onset of COVID-19 and autoimmune haemolytic anaemia Autoimmune hemolytic anemia associated with Covid-19 infection Few data are available about the risk of COVID-19 infection in persons with hematological cancer, but controversy whether these persons have the same clinical signs and outcomes.
    keywords: case; covid-19; infection
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        item: #6607 of 7819
          id: cord-340728-8jvg3sir
      author: Lindsay, Karen J.
       title: Invited editorial from the social media editor of JPRAS; Leadership in the time of COVID-19
        date: 2020-07-16
       words: 2315
      flesch: 49
     summary: The Reconstructive Surgical Trial Network (RSTN) in the UK was already pushing this agenda in the advancement of plastic surgery research. The team advocate for the use of high quality reusable PPE for health and social care workers, they have been endorsed by the Confederation of British Surgeons, and engaged with health service and government officials locally, regionally and nationally to deliver their aims.
    keywords: covid-19; healthcare; leadership; pandemic; plastic; surgery; time
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        item: #6608 of 7819
          id: cord-340738-2pufvc67
      author: AbdAllah, Mohamed
       title: Herd-immunity against COVID-19: Is it enough to stop a second wave?
        date: 2020-11-12
       words: 683
      flesch: 53
     summary: Many reports discussed the durability of Post-infection immunity after COVID-19 infection. Dear Editor, Humanity faces its greatest challenge in the last 100 years as the outbreak of coronavirus disease 2019 (COVID-19) caused more than 17 million confirmed cases all over the world [1] . About eighty percent of COVID-19 cases are asymptomatic or presented with mild symptoms.
    keywords: covid-19; immunity
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        item: #6609 of 7819
          id: cord-340752-367jr3so
      author: Mitchell, Rob
       title: Emergency departments and the COVID-19 pandemic: making the most of limited resources
        date: 2020-04-01
       words: 361
      flesch: 60
     summary: Emerg Med J DOI: 10.1136/emermed-2020-209660 sha: doc_id: 340752 cord_uid: 367jr3so nan Emergency departments and the COVID-19 pandemic: making the most of limited resources Dear Editor, The coronavirus disease 2019 (COVID-19) pandemic will stretch hospital resources all over the world. 2 Content was developed by a working party of ACEM's Global Emergency Care Committee and included EC clinicians from Timor Leste, Vanuatu, Papua New Guinea and Solomon Islands.
    keywords: covid-19; guide
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        item: #6610 of 7819
          id: cord-340796-0l9v9f1e
      author: García-Manzanedo, Sofía
       title: SÍNDROME DE GUILLAIN-BARRÉ TRAS INFECCIÓN POR COVID-19
        date: 2020-07-09
       words: 924
      flesch: 30
     summary: En concreto nuestro paciente presentó debilidad en la musculatura facial bilateral, así como de la musculatura orofaríngea y cervical, con preservación de la fuerza y los reflejos de miembros inferiores, lo que es compatible con una variante del SGB conocida como debilidad faringo-cérvico-braquial. Algunas de las manifestaciones neurológicas pueden aparecer incluso antes de la neumonía o síntomas respiratorios y, por tanto, es importante tener en cuenta este hecho.
    keywords: afectación; con; covid-19; por
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        item: #6611 of 7819
          id: cord-340799-1awmtj52
      author: Krajewska, Joanna
       title: Review of practical recommendations for otolaryngologists and head and neck surgeons during the COVID-19 pandemic: Recommendations for otolaryngologists during the COVID-19 pandemic
        date: 2020-06-06
       words: 7948
      flesch: 41
     summary: The estimated prevalence of cough in COVID-19 patients ranged between 60 and 82%, while the prevalence of dyspnea ranged between 9% and 37% [25] . Similarly, no recommendation for performing tracheotomy within 7 days in COVID-19 patients with ARDS has been proposed [47] .
    keywords: cases; cov-2; covid-19; head; individuals; infection; nasal; neck; pandemic; patients; procedures; risk; sars; surgery; tracheostomy; virus
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        item: #6612 of 7819
          id: cord-340805-qbvgnr4r
      author: Ioannidis, John P.A.
       title: Forecasting for COVID-19 has failed
        date: 2020-08-25
       words: 6093
      flesch: 52
     summary: The possibility of calibrating model predictions for looking at extremes rather than just means is sensible, especially in early days of pandemics, when much is unknown about the virus and its epidemiological footprint. However, even forecasting built directly on data alone fared badly, 11, 12 failing not only in ICU bed predictions ( Figure 1 ) but even in next day death predictions when issues of long-term chaotic behavior do not come into play (Figures 2 and 3 ).
    keywords: covid-19; data; deaths; distribution; epidemic; forecasting; impact; models; predictions
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        item: #6613 of 7819
          id: cord-340826-2530zdeq
      author: Hwang, Jong-moon
       title: Neurological diseases as mortality predictive factors for patients with COVID-19: a retrospective cohort study
        date: 2020-07-08
       words: 2932
      flesch: 47
     summary: CONCLUSIONS: Clinicians should closely monitor and manage the symptoms of COVID-19 patients who are over the age of 70 years or have chronic lung disease or AD. Regarding underlying diseases, we found that chronic lung disease and AD increase the mortality rate in COVID-19 patients.
    keywords: age; chronic; covid-19; disease; patients; study
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        item: #6614 of 7819
          id: cord-340848-gdi4c92i
      author: Moon, M. Jae
       title: Fighting COVID‐19 with Agility, Transparency, and Participation: Wicked Policy Problems and New Governance Challenges
        date: 2020-05-20
       words: 4212
      flesch: 38
     summary: In fact, 74.4 percent of respondents to a national survey answered that government information about COVID-19 was transparent, and more than 60 percent replied that they trust the government (Institute of Future Government 2020). However, a policy of transparency eventually leads to a trust surplus in the long run because the public will then accept the government as a reliable source of information and come to trust government actions (Moon 2020) .
    keywords: citizens; covid-19; government; mers; patients; policy; public; south
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        item: #6615 of 7819
          id: cord-340851-lnv8yi9l
      author: Perkins, Alex
       title: Optimal control of the COVID-19 pandemic with non-pharmaceutical interventions
        date: 2020-04-23
       words: 6955
      flesch: 51
     summary: key: cord-340851-lnv8yi9l authors: Perkins, Alex; Espana, Guido title: Optimal control of the COVID-19 pandemic with non-pharmaceutical interventions date: 2020-04-23 journal: nan DOI: 10.1101/2020.04.22.20076018 sha: doc_id: 340851 cord_uid: lnv8yi9l Given that the pandemic is already underway and controls have already been initiated, we calibrated our model to data from the US and focused our analysis on optimal controls from May 2020 through December 2021.
    keywords: april; control; covid-19; license; medrxiv; model; optimal; preprint
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        item: #6616 of 7819
          id: cord-340855-y5o8dvf4
      author: Meng, Zibo
       title: Predicted value of coagulation function for prognosis and admission time to negative RT‐PCR detection in non‐critical COVID‐19 patients
        date: 2020-06-04
       words: 841
      flesch: 33
     summary: We conducted retrospective study between February 13, 2020 and March 13, 2020 in Cancer Center of Wuhan Union Hospital (Wuhan, China), which was designated hospital to centralized admission COVID-19 patients since February 13, 2020, to reveal the potential role for coagulation parameters in COVID-19 patients. 1 Alex et al suggested the use of thromboprophylaxis in COVID-19 patients, particularly those with evidence of activation of the coagulation system on admission.
    keywords: coagulation; covid-19; patients
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        item: #6617 of 7819
          id: cord-340880-2qop8tcp
      author: Hyman, Jaime B.
       title: Timing of Intubation and In-Hospital Mortality in Patients With Coronavirus Disease 2019
        date: 2020-10-21
       words: 3669
      flesch: 34
     summary: The challenge for clinicians is to determine which hypoxemic COVID-19 patients are at greatest risk of further respiratory decompensation in order to optimize timing of intubation and initiation of mechanical ventilation, without intubating patients who could have done well on noninvasive ventilation. In this large, multihospital, retrospective cohort study of COVID-19 positive patients who underwent mechanical ventilation during the peak of the COVID-19 pandemic in New York City, we found that timing of intubation had a small but significant association with improved survival.
    keywords: admission; hospital; intubation; mortality; patients; time; ventilation
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        item: #6618 of 7819
          id: cord-340884-9blq86zo
      author: Prakash, Elapulli Sankaranarayanan
       title: Am I a “COVID-19 Patient” or “a Patient With COVID-19”?
        date: 2020-08-24
       words: 628
      flesch: 43
     summary: key: cord-340884-9blq86zo authors: Prakash, Elapulli Sankaranarayanan title: Am I a “COVID-19 Patient” or “a Patient With COVID-19”? date: 2020-08-24 journal: J Patient Exp DOI: 10.1177/2374373520951669 sha: doc_id: 340884 cord_uid: 9blq86zo nan In the context of health care professionals' communication with individual patients, I've wondered if repeated usage of concise phrases like COVID-19 patient, instead of saying patient with COVID-19 (the intended meaning of the phrase COVID-19 patient), might come across as offensive though no offense is intended. Similarly, those affected by COVID-19 are not COVID-19 patients; rather, they are patients or individuals with COVID-19.
    keywords: covid-19; patient
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        item: #6619 of 7819
          id: cord-340887-k88hchau
      author: Khusid, Johnathan A.
       title: Well‐Being and Education of Urology Residents During the COVID‐19 Pandemic: Results of an American National Survey
        date: 2020-05-27
       words: 3043
      flesch: 39
     summary: Another potentially modifiable predictor of urology resident anxiety and depression was perception of support by the residency program. Several potential actions, which could be taken by urology residency program directors and hospital administration, may optimize urology resident well‐being, morale, and education.
    keywords: anxiety; covid-19; pandemic; residents; severity; urology; work
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        item: #6620 of 7819
          id: cord-340889-ff35696d
      author: Ko, Nai-Ying
       title: Changes in Sex Life among People in Taiwan during the COVID-19 Pandemic: The Roles of Risk Perception, General Anxiety, and Demographic Characteristics
        date: 2020-08-11
       words: 5571
      flesch: 44
     summary: A study comparing sexual behaviors among Turkish women during the pandemic with 6-12 months prior to the pandemic found that sexual desire and frequency of intercourse significantly increased during the COVID-19 pandemic, whereas quality of sexual life significantly decreased; the pandemic is associated with decreased desire for pregnancy, decreased female contraception, and increased menstrual disorders [15] . A study on Turkish women found that despite the increased frequency of sexual intercourse during the COVID-19 pandemic, quality of sexual life decreased during the pandemic [15] .
    keywords: activity; anxiety; covid-19; life; pandemic; risk; sex; sex life; study
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        item: #6621 of 7819
          id: cord-340921-tg62xw8v
      author: Jee, Youngmee
       title: WHO International Health Regulations Emergency Committee for the COVID-19 outbreak
        date: 2020-03-19
       words: 1906
      flesch: 42
     summary: Since PHEIC declaration requires a consensus of committee members, COVID-19 was not declared as a PHEIC at the first meeting held on January 22-23, 2020 as a consensus was not reached. As stated in the IHR, upon PHEIC declaration, WHO makes various efforts to internationally coordinate the necessary support in order to terminate the PHEIC status as soon as possible.
    keywords: covid-19; health; pheic; research
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        item: #6622 of 7819
          id: cord-340930-5cavkdde
      author: Cheung, Victor Kai-Lam
       title: Investigating effects of healthcare simulation on personal strengths and organizational impacts for healthcare workers during COVID-19 pandemic: A cross-sectional study
        date: 2020-07-16
       words: 2624
      flesch: 30
     summary: This cross-sectional study aimed at evaluating impacts of healthcare simulation training, either in-situ or lab-based, on personal strengths of healthcare workers (HCWs) and organizational outcomes during the COVID-19 pandemic. Between 05 February and 18 March 2020, 101 sessions of simulation training were conducted in “In-Situ” at either Accident & Emergency Department (20, 20%) or Intensive Care Unit (15, 14%) and “Lab-based” for Isolation (30, 30%) and General Wards (36, 36%).
    keywords: control; covid-19; hcws; healthcare; hospital; simulation; situ; strengths; training
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        item: #6623 of 7819
          id: cord-340937-6mpob1nx
      author: Varshney, Mohit
       title: Initial psychological impact of COVID-19 and its correlates in Indian Community: An online (FEEL-COVID) survey
        date: 2020-05-29
       words: 3665
      flesch: 46
     summary: The survey collected data on socio-demographic and clinical variables related to COVID-19 (based on the current knowledge); along with measuring psychological impact with the help of Impact of Event–revised (IES-R) scale. The survey collected data on socio-demographic and clinical variables related to COVID-19 (based on the current knowledge); along with measuring psychological impact with the help of Impact of Eventrevised (IES-R) scale.
    keywords: coronavirus; covid-19; health; impact; outbreak; respondents; study; survey
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        item: #6624 of 7819
          id: cord-340938-mk01k235
      author: Xu, Kandi
       title: Application of ordinal logistic regression analysis to identify the determinants of illness severity of COVID-19 in China
        date: 2020-07-07
       words: 4150
      flesch: 42
     summary: A retrospective cohort of COVID-19 patients from four hospitals in three provinces in China was established, and 598 patients were included from 1 January to 8 March 2020, and divided into moderate, severe and critical illness group. Our findings highlight that the identified determinants may help to predict the risk of developing more severe illness among COVID-19 patients and contribute to optimising arrangement of health resources.
    keywords: covid-19; group; illness; onset; patients; risk; severity; study
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        item: #6625 of 7819
          id: cord-340942-oatf59k0
      author: Magalhães, Jurandy Júnior Ferraz de
       title: Epidemiological and clinical characteristics of the first 557 successive patients with COVID-19 in Pernambuco state, Northeast Brazil
        date: 2020-09-21
       words: 3954
      flesch: 55
     summary: Since then, the number of COVID-19 cases in Brazil has increased steadily and the country has become the third most affected in the world after the USA and India. For that, the QGIS software (https://qgis. org/en/site/) was used to plot home addresses and the Kernel Density Estimation method was applied to identify the neighborhoods with the highest concentration of COVID-19 cases.
    keywords: cases; covid-19; disease; patients; pernambuco; sars; study; years
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        item: #6626 of 7819
          id: cord-340984-blkhfhe2
      author: Gklinos, Panagiotis
       title: Neurological manifestations of COVID-19: a review of what we know so far
        date: 2020-05-26
       words: 2677
      flesch: 41
     summary: The above-mentioned clinical case series in Wuhan, China, showed that 36.4% of COVID-19 patients had neurological symptoms at onset. Continuing documentation of neurological symptoms and signs, timely CSF testing, EEG, and brain autopsies of COVID-19 patients who did not survive may help us understand better the neurological manifestations of the novel coronavirus as well as the pathophysiological mechanisms of CNS involvement.
    keywords: coronavirus; cov-2; covid-19; patients; sars; symptoms
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        item: #6627 of 7819
          id: cord-340992-88t1c0zs
      author: Nikolai, Lea A
       title: Asymptomatic SARS Coronavirus 2 infection: Invisible yet invincible
        date: 2020-09-03
       words: 3092
      flesch: 33
     summary: When assessing public health risks raised by asymptomatic COVID-19 cases it is important to determine whether the infectivity varies between asymptomatic, presymptomatic and symptomatic individuals. The estimated proportion of asymptomatic infections ranges from 18% to 81%.
    keywords: asymptomatic; children; cov-2; covid-19; individuals; infections; presymptomatic; sars
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        item: #6628 of 7819
          id: cord-341060-otvoo99j
      author: Alharthy, Abdulrahman
       title: Thrombolysis in severe COVID-19 pneumonia with massive pulmonary embolism
        date: 2020-07-30
       words: 914
      flesch: 41
     summary: Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV Admitted to ICUs of the Lombardy Region, Italy Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19) First case of COVID-19 complicated with fulminant myocarditis: a case report and insights COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options COVID-19 and the Heart Cardiovascular Considerations for Patients, Health Care Workers, and Health Systems During the COVID-19 Pandemic Endothelial cell infection and endotheliitis in COVID-19 Catheter-directed thrombolysis in COVID-19 pneumonia with acute PE: Thinking beyond the guidelines A prospective, longitudinal evaluation of point-ofcare lung ultrasound in critically ill patients with severe COVID-19 pneumonia Insights from the MAGELLAN and MARINER Trials Severe pulmonary embolism in COVID-19 patients: a call for increased awareness Deep Vein Thrombosis in Hospitalized Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: Prevalence, Risk Factors, and Outcome China Medical Treatment Expert Group for Covid-19 Clinical Characteristics of Coronavirus Disease 2019 in China.
    keywords: care; covid-19; patient
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        item: #6629 of 7819
          id: cord-341085-2stfkwp3
      author: Haseli, Sara
       title: Lobar Distribution of COVID-19 Pneumonia Based on Chest Computed Tomography Findings; A Retrospective Study
        date: 2020-04-18
       words: 3205
      flesch: 46
     summary: Evaluating chest CT findings in combination with clinical symptoms and laboratory tests aids in the medical decision making for COVID-19 disease. Pneumonia Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Chest CT Severity Score: An Imaging Tool for Assessing Severe COVID-19 Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study Chest CT Findings in Cases from the Cruise Ship âȂIJDiamond PrincessâȂİ with Coronavirus Disease CT imaging features of 2019 novel coronavirus Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia
    keywords: chest; covid-19; ggo; imaging; patients; study
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        item: #6630 of 7819
          id: cord-341105-3uvbfp8c
      author: Li, Dian-Jeng
       title: COVID-19-Related Factors Associated with Sleep Disturbance and Suicidal Thoughts among the Taiwanese Public: A Facebook Survey
        date: 2020-06-22
       words: 4435
      flesch: 43
     summary: Studies predicting factors associated with mental health problems will enhance understanding and help develop timely prevention and intervention strategies to enhance public mental health during COVID-19 pandemics [8] . A novel coronavirus outbreak of global health concern COVID-19 outbreak: Migration, effects on society, global environment and prevention The Socio-Economic Implications of the Coronavirus and COVID-19 Pandemic: A Review COVID-19 Press Releases D-dimer and TAT measurement in patients with deep venous thrombosis: Utility in diagnosis and judgement of anticoagulant treatment effectiveness Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: A web-based cross-sectional survey Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease Timely mental health care for the 2019 novel coronavirus outbreak is urgently needed Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China Mental health problems and social media exposure during COVID-19 outbreak Impact of the COVID-19 Pandemic on Mental Health and Social Support among Adult Egyptians Suicide risk and prevention during the COVID-19 pandemic Facebook Recruitment of Young Adult Smokers for a Cessation Trial: Methods, Metrics, and Lessons Learned Predictive validity of a five-item symptom checklist to screen psychiatric morbidity and suicide ideation in general population and psychiatric settings Anxiety, worry and cognitive risk estimate in relation to protective behaviors during the 2009 influenza A/H1N1 pandemic in Hong Kong: Ten cross-sectional surveys Psychosocial impact among the public of the severe acute respiratory syndrome epidemic in Taiwan Use of Rapid Online Surveys to Assess People's Perceptions during Infectious Disease Outbreaks: A Cross-sectional Survey on COVID-19 General hospital staff worries, perceived sufficiency of information and associated psychological distress during the A/H1N1 influenza pandemic Worry experienced during the 2015 Middle East Respiratory Syndrome (MERS) pandemic in Korea COVID-19 Related Misinformation on Social Media: A Qualitative Study from Iran Misinformation of COVID-19 on the Internet: Infodemiology Study.
    keywords: covid-19; disturbance; health; sleep; study; support; thoughts
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        item: #6631 of 7819
          id: cord-341126-i8wr8h4x
      author: Hyung, Jaewon
       title: The Asian Approach to the Management of GI Cancer Patients During the COVID-19 Pandemic Era
        date: 2020-07-09
       words: 1350
      flesch: 43
     summary: The outbreak affected the daily practice of cancer patient management in Japan. This highly contagious disease has significantly affected management of cancer patients in Asia, as well as other regions of the world.
    keywords: cancer; covid-19; patients
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        item: #6632 of 7819
          id: cord-341132-arhpqgl6
      author: Gangemi, Sebastiano
       title: Rich at risk: socio-economic drivers of COVID-19 pandemic spread
        date: 2020-07-01
       words: 1652
      flesch: 33
     summary: However, according to the report, albeit nearly any country in the world reported COVID-19 cases, noteworthy differences are present between continents as well as between single countries, with the largest amount of cases being reported in Americas and Europe, and a significantly lower prevalence observed in Africa, driving one to hypothesize either geographical or socio-economic factors driving such unbalance. As displayed in Table 1 , the ratio of COVID-19 cases per million people was found to be significantly correlated with several socio-economic indicators, as with transportation-related factors.
    keywords: countries; covid-19; number; population
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        item: #6633 of 7819
          id: cord-341156-dw15n4f4
      author: Nash, Meredith
       title: Caring during COVID‐19: A gendered analysis of Australian university responses to managing remote working and caring responsibilities
        date: 2020-06-02
       words: 7053
      flesch: 39
     summary: This article fills a key knowledge gap by examining how Australian universities are supporting academics to manage remote work and caring during the COVID‐19 pandemic. We argue that this brand of 'careerist masculinity' has become more visible during the pandemic when Australian universities instructed staff to work remotely (O'Connor, O'Hagan, & Brannen, 2015) .
    keywords: article; australian; care; caring; copyright; covid-19; institutions; leave; rights; universities; women; work; working
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        item: #6634 of 7819
          id: cord-341175-rks0l0q0
      author: Essa, Musthafa Mohamed
       title: Possible role of tryptophan and melatonin in COVID-19
        date: 2020-08-21
       words: 823
      flesch: 27
     summary: Systemic complications related to COVID-19 infection are being treated with therapeutic drugs such as corticosteroid (dexamethasone) or biological agents (antibodies) against the cytokine storm (interleukins: IL-1 and IL-6, and TNF-α). [7] [8] [9] Here, we discuss the potential of using tryptophan and its metabolites including melatonin to boost the immune system in fighting COVID-19 infection (see Figure 1) .
    keywords: covid-19; patients; tryptophan
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        item: #6635 of 7819
          id: cord-341187-jqesw4e8
      author: Yu, Xinhua
       title: Modeling Return of the Epidemic: Impact of Population Structure, Asymptomatic Infection, Case Importation and Personal Contacts
        date: 2020-08-27
       words: 3803
      flesch: 41
     summary: Then some percent of exposed young people become symptomatic cases ( ), and some become asymptomatic cases ( ). On the other hand, a higher infectivity of asymptomatic cases (e.g., 100% of symptomatic cases) results in a fast developing and narrow epidemic curve which reaches the peak within 60 days.
    keywords: asymptomatic; cases; covid-19; epidemic; model; people
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        item: #6636 of 7819
          id: cord-341197-e8m4oxma
      author: Soleimani, Abbas
       title: Effects of angiotensin receptor blockers (ARBs) on in-hospital outcomes of patients with hypertension and confirmed or clinically suspected COVID-19
        date: 2020-09-12
       words: 3649
      flesch: 43
     summary: After adjustment for the same confounders in the whole cohort and hypertensive patients, Cox proportional hazard models (Figure 1 and Supplementary We observed no significant difference between female and male patients, either in the whole cohort or hypertensive patients, in terms of in-hospital outcomes; however, female hypertensive patients were more likely to incur ARDS rather than male hypertensive patients (P=0.014) (Supplementary Table 4 ). [15] [16] nevertheless, some studies suggest that ACEI/ARBs were associated with improved outcomes in COVID-19 patients.
    keywords: aki; arbs; covid-19; disease; hospital; hypertensive; outcomes; patients
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        item: #6637 of 7819
          id: cord-341202-1pg7rq2d
      author: Manicone, Francesca
       title: The last bed dilemma burns out COVID-19 triage: a viewpoint from Medical and Law students
        date: 2020-08-12
       words: 1322
      flesch: 46
     summary: In our view, this solution would suitably respond to two essential problems: a patient otherwise discarded by the guidelines might be given a chance to survive based on physician clinical experience whereas, if nonetheless the meeting withheld the bed, the physician would relieve his stress, sharing, to the greatest extent possible, the burden with the team. As its etymology suggests, trier means the culling, the sorting and allocation of patients, treatments or resources, historically attempted by a plethora of methods.
    keywords: care; covid-19; health; patient
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        item: #6638 of 7819
          id: cord-341220-b2u8gswb
      author: Ben-Ezra, Menachem
       title: The association between COVID-19 WHO non-recommended behaviors with psychological distress in the UK population: A preliminary study
        date: 2020-08-20
       words: 1462
      flesch: 41
     summary: A national study of 1293 participants from the UK recorded location, underlying medical conditions and non-recommended behaviors along with psychological distress. We examine the association between psychological distress, location (London the epicenter of COVID-19, versus elsewhere), underlying health conditions associated with increased mortality from covid-19 and the adoption of non-recommended behaviors with psychological distress.
    keywords: behaviors; covid-19; distress
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        item: #6639 of 7819
          id: cord-341256-2j0tqmd4
      author: An, Ying
       title: Prevalence of depression and its impact on quality of life among frontline nurses in emergency departments during the COVID-19 outbreak
        date: 2020-07-15
       words: 2370
      flesch: 42
     summary: Similar to previous findings (Li et al., 2017; , current smoking was significantly associated with higher risk depression in this study. Considering the negative impact of depression on quality of patient care and nurses’ quality of life, a heightened awareness and early treatment of depression for frontline ED nurses should be provided.
    keywords: covid-19; depression; nurses
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        item: #6640 of 7819
          id: cord-341259-1768lp0a
      author: Lazarus, G.
       title: High admission blood glucose is an independent risk factor of poor prognosis in COVID-19: A systematic review and dose-response meta-analysis
        date: 2020-09-27
       words: 5122
      flesch: 41
     summary: A Meta-Analysis of Observational Studies A guide to systematic review and meta-analysis of prognostic factor studies Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement Admission blood glucose level as a prognostic factor for COVID-19 severity and mortality: a systematic review Clinical management of COVID-19: interim guidance -27 Evaluation of the quality of prognosis studies in systematic reviews Judging the quality of evidence in reviews of prognostic factor research: adapting the GRADE framework Methodological issues and recommendations for systematic reviews of prognostic studies: an example from cardiovascular disease Meta-analysis in clinical trials Contour-enhanced meta-analysis funnel plots help distinguish publication bias from other causes of asymmetry Bias in meta-analysis detected by a simple, graphical test R: A language and environment for statistical computing Higher Comorbidities and Early Death is Characteristic of Hospitalized African-American Patients with COVID-19. 32, 35, 43 Furthermore, our findings indicated that at-admission hyperglycemia was associated with poorer outcomes regardless of prior diabetes status, suggesting the existence of a more direct link between glycemic status and poor COVID-19 outcomes.
    keywords: admission; covid-19; license; medrxiv; patients; preprint; review; studies
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        item: #6641 of 7819
          id: cord-341288-x0wuj26f
      author: Moreira, Bruno Lima
       title: COVID-19 and acute pulmonary embolism: what should be considered to indicate a computed tomography pulmonary angiography scan?
        date: 2020-06-01
       words: 1728
      flesch: 38
     summary: key: cord-341288-x0wuj26f authors: Moreira, Bruno Lima; Santana, Pablo Rydz Pinheiro; Zanetti, Gláucia; Marchiori, Edson title: COVID-19 and acute pulmonary embolism: what should be considered to indicate a computed tomography pulmonary angiography scan? date: 2020-06-01 journal: Here, we present a case of a patient with COVID-19 who developed acute pulmonary embolism.
    keywords: acute; covid-19; patients
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        item: #6642 of 7819
          id: cord-341300-fkdydf4u
      author: Avendano-Sola, C.
       title: Convalescent Plasma for COVID-19: A multicenter, randomized clinical trial
        date: 2020-09-01
       words: 3840
      flesch: 48
     summary: Regarding CP, a first RCT, prematurely stopped by logistic reasons, did not demonstrate benefit in COVID-19 patients with a median of 30 days of symptoms. First, administration of CP in COVID-19 patients appears to be safe also in a well-monitored, randomized, controlled design.
    keywords: available; covid-19; license; medrxiv; patients; perpetuity; preprint
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        item: #6643 of 7819
          id: cord-341304-jdvzpvdx
      author: Pata, Rama Kanth
       title: Human Immunodeficiency Virus: A Dark Cloud With Silver Lining During the COVID-19 Pandemic
        date: 2020-07-20
       words: 1873
      flesch: 46
     summary: The leading cause of mortality in COVID-19 patients is acute respiratory distress syndrome (ARDS). Clinical trials have shown varying levels of effectiveness of lopinavir-boosted ritonavir on reducing mortality rates in COVID-19 patients.
    keywords: coronavirus; covid-19; days; hiv; patients
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        item: #6644 of 7819
          id: cord-341309-li3slzw6
      author: McGough, S. F.
       title: Modeling COVID19 mortality in the US: Community context and mobility matter
        date: 2020-06-20
       words: 3087
      flesch: 41
     summary: These effect estimates also incorporate any changes in social mobility over time. Declines in mobility were associated with up to 15% lower mortality rates relative to pre-social distancing levels of mobility, but effects were lagged between 25-30 days.
    keywords: covid-19; distancing; license; mobility; mortality; preprint
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        item: #6645 of 7819
          id: cord-341314-1mav631s
      author: Caso, Valeria
       title: No lockdown for neurological diseases during COVID19 pandemic infection
        date: 2020-04-08
       words: 1706
      flesch: 36
     summary: At the end of the procedure, the patient is transferred to the Infectious Disease ward or a dedicated Intensive Care Unit (ICU) dedicated to COVID-19 patients based on neurological conditions. Baracchini et al., in this brief report published in this current issue, are sharing how the University Hospital of Padua, with a catchment area of about 950.000 people, structured a pathway for acute stroke patients before admitting them to our Stroke Unit [9] .
    keywords: care; covid-19; patients; stroke; unit
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        item: #6646 of 7819
          id: cord-341323-mw352rr1
      author: Logie, Carmen H
       title: Lessons learned from HIV can inform our approach to COVID‐19 stigma
        date: 2020-05-04
       words: 1562
      flesch: 48
     summary: Experts offer ethical guidance Fair Allocation of Scarce Medical Resources in the Time of Covid-19 Community-based interventions that work to reduce HIV stigma and discrimination: results of an evaluation study in Thailand Stigma in health facilities: why it matters and how we can change it Combating HIV stigma in health care settings: what works? We can leverage our four decades of HIV research to understand and address COVID-19 stigma.
    keywords: covid-19; health; hiv; persons; stigma
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        item: #6647 of 7819
          id: cord-341359-c34gyuv6
      author: Larson, Derek T
       title: Clinical Outcomes of Coronavirus Disease 2019 With Evidence-based Supportive Care
        date: 2020-05-30
       words: 1206
      flesch: 35
     summary: Notes A pneumonia outbreak associated with a new coronavirus of probable bat origin Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Clinical features and short-term outcomes of 221 patients with COVID-19 in Wuhan Effectiveness of convalescent plasma therapy in severe COVID-19 patients An epidemiological study on COVID-19: a rapidly spreading disease Characteristics of COVID-19 infection in Beijing The risks of prescribing hydroxychloroquine for treatment of COVID-19-first, do no harm Covid-19-a reminder to reason Acknowledgments. We believe this is attributable to multiple factors, including a focus on supportive care that is well established to benefit patients and a conservative intubation strategy.
    keywords: care; covid-19; disease; patients
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        item: #6648 of 7819
          id: cord-341381-jzjhhn23
      author: Davis, M.
       title: Intimate Partner Violence Victimization and Perpetration among U.S. Adults during COVID-19: A Brief Report
        date: 2020-06-09
       words: 1953
      flesch: 47
     summary: In this study, self-reported COVID-19 impacted respondents had an increased risk of IPV victimization and perpetration. The J-IPV is a 4-item screening tool developed to assess IPV victimization and perpetration in patients entering substance abuse treatment 12 .
    keywords: covid-19; ipv; license; medrxiv; preprint
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        item: #6649 of 7819
          id: cord-341387-ovwiqmmj
      author: Marone, Enrico M.
       title: Characteristics of venous thromboembolism in COVID-19 patients: a multicenter experience from Northern Italy.
        date: 2020-07-14
       words: 1475
      flesch: 44
     summary: key: cord-341387-ovwiqmmj authors: Marone, Enrico M.; Bonalumi, Giovanni; Curci, Ruggiero; Arzini, Aldo; Chierico, Simona; Marazzi, Giulia; Diaco, Domenico A.; Rossini, Rosa; Boschini, Stefano; Rinaldi, Luigi F. title: Characteristics of venous thromboembolism in COVID-19 patients: a multicenter experience from Northern Italy. date: 2020-07-14 journal: This study aims to outline the main characteristics of deep venous thrombosis (DVT) and pulmonary embolism (PE) in COVID-19 patients, based on experience of four high-volume COVID-19 hospitals in Northern Italy.
    keywords: covid-19; dvt; patients; vte
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        item: #6650 of 7819
          id: cord-341389-1o0ey67l
      author: Tay, Kiang Hiong
       title: Reconfiguring the radiology leadership team for crisis management during the COVID-19 pandemic in a large tertiary hospital in Singapore
        date: 2020-08-11
       words: 3694
      flesch: 42
     summary: Similar disease outbreak teams are established in all major public healthcare institutions to interface with MOH and coordinate responses and efforts in their respective institutions. Informed consent Written informed consent was not required for this study because it is a special report on radiology leadership.
    keywords: covid-19; disease; domain; dotf; imaging; leadership; management; outbreak; radiology; staff
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        item: #6651 of 7819
          id: cord-341397-gl8xzzdv
      author: Bhavani, Sivasubramanium V.
       title: Novel Temperature Trajectory Subphenotypes in COVID-19
        date: 2020-07-21
       words: 1401
      flesch: 37
     summary: Further research is needed using multicenter data to investigate the prognostic and phenotypic potential of temperature trajectory subphenotypes in COVID-19. Group 1 (n=139, 20%) had normal presenting temperatures that increased over the subsequent 72 hours; Group 2 (n=97, 14%) had higher presenting temperatures but decreased over time; Group 3 (n=277, 40%) had normal body temperatures throughout without significant changes; Group 4 (n=183, 26%) had low body temperatures (Figure 1) .
    keywords: covid-19; group; subphenotypes; temperature
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        item: #6652 of 7819
          id: cord-341420-bfzto2lz
      author: Mohamed, Chekkal
       title: Prevention and treatment of COVID-19-associated hypercoagulability: recommendations of the Algerian society of transfusion and hemobiology
        date: 2020-10-03
       words: 1048
      flesch: 32
     summary: In adult patients with COVID-19-associated DIC presenting with bleeding or candidates for an invasive procedure, platelet transfusion should be performed (3 à 6 x 10 11 ) if the platelet count is < 50 x 10 9 /L, 15 to 25 ml/Kg of fresh frozen plasma (FFP) if the PT ratio is >1.5 and fibrinogen or cryoprecipitate if the fibrinogen level is < 1.5 g/l. It is recommended to continue anticoagulant treatment with LMWHs at prophylactic doses or with direct oral anticoagulants for up to 45 days in patients with added risk factors for thrombosis: e.g. prolonged immobilization, age > Coagulation dysfunction is one of the major causes of death in patients with severe COVID-19.
    keywords: covid-19; dic; patients; risk
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        item: #6653 of 7819
          id: cord-341435-b36h69r1
      author: Dawson, Patrick
       title: Loss of Taste and Smell as Distinguishing Symptoms of COVID-19
        date: 2020-06-21
       words: 1693
      flesch: 43
     summary: This investigation provided an opportunity to identify household COVID-19 cases and describe their symptom profiles, including loss of taste and smell, prior to diagnosis. Nasal congestion alone is unlikely to explain the taste and smell alterations, as one-third of patients reporting loss of taste and/or smell did not report nasal congestion; other analyses have shown an even smaller proportion of COVID-19 cases with concurrent nasal congestion (9) .
    keywords: covid-19; loss; smell; symptoms; taste
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        item: #6654 of 7819
          id: cord-341475-v6ue6hhf
      author: Rahimi, Farid
       title: Criticality of physical/social distancing, handwashing, respiratory hygiene, and face‐masking during the COVID‐19 pandemic and beyond
        date: 2020-08-09
       words: 1049
      flesch: 44
     summary: -ABC News What do antibody tests for SARS-CoV-2 tell us about immunity? COVID-19 and the cardiovascular system Australian/New Zealand consensus statement Lost smell and taste hint COVID-19 can target the nervous system ACE2: The key molecule for understanding the pathophysiology of severe and critical conditions of COVID-19: Demon or angel? By the end of January 2020, the World Health Organization (WHO) announced the outbreak as a public-health emergency and later, on March 11, declared the COVID-19 a pandemic.
    keywords: covid-19; distancing; pandemic
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        item: #6655 of 7819
          id: cord-341479-lj0brkbx
      author: Caviglia, Marta
       title: The National Emergency Medical Service Role During the COVID-19 Pandemic in Sierra Leone
        date: 2020-09-22
       words: 2206
      flesch: 38
     summary: First and foremost, NEMS ambulance teams were in charge of transporting suspect, probable, or confirmed cases to referral health care facilities following the standard operating procedures (SOPs) defined by the CMP. This perception of fear and mistrust in the health care system recurred to some extent during the COVID-19 pandemic, with NEMS ambulance teams experiencing multiple cases of violence, including acts of vandalism against ambulances and refusal to be transported to treatment centers.
    keywords: ambulance; cases; covid-19; health; leone; nems; sierra
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        item: #6656 of 7819
          id: cord-341480-thia28sh
      author: Aminlari, Amir
       title: A Case of COVID-19 Diagnosed At Home with Portable Ultrasound and Confirmed with Home Serology Test
        date: 2020-10-12
       words: 554
      flesch: 34
     summary: The potential for home diagnosis and monitoring could reduce infectious risk for other patients and healthcare providers, limit use of finite hospital resources and enable better social distancing/isolation practices. Conclusions Novel times call for novel solutions and our case demonstrates one possible path for home diagnosis and monitoring of COVID-19.
    keywords: home; ultrasound
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        item: #6657 of 7819
          id: cord-341503-3cvtoc2j
      author: Jaiswal, J.
       title: Disinformation, Misinformation and Inequality-Driven Mistrust in the Time of COVID-19: Lessons Unlearned from AIDS Denialism
        date: 2020-05-21
       words: 2556
      flesch: 27
     summary: USA Today Tuskegee always looms in our minds: some fear black Americans, hardest hit by coronavirus, may not get vaccine Study: nearly a third of Americans believe a conspiracy theory about the origins of the coronavirus Medical apartheid: the dark history of medical experimentation on black Americans from colonial times to the present Ubiquitous yet unclear: a systematic review of medical mistrust Medical mistrust and PrEP perceptions among transgender women: a cluster analysis The association of cultural and structural factors with perceived medical mistrust among young adult Latinos in rural Oregon Medical mistrust, racism, and delays in preventive health screening among African-American men Does discrimination breed mistrust? Much of the evidence needed to fully inform clinical and public health responses is not yet available, making COVID-19 uniquely vulnerable to a proliferation of disinformation, misinformation, and medical mistrust, including what are often called conspiracy beliefs [6, 7] .
    keywords: beliefs; conspiracy; covid-19; disinformation; health; hiv; mistrust
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        item: #6658 of 7819
          id: cord-341512-nhdx944g
      author: Tanno, Luciana Kase
       title: CORONAVIRUS DISEASE (COVID)-19: WORLD HEALTH ORGANIZATION DEFINITIONS AND CODING TO SUPPORT THE ALLERGY COMMUNITY AND HEALTH PROFESSIONALS
        date: 2020-05-11
       words: 972
      flesch: 36
     summary: Although there is still no specific treatment to the COVID-19, knowledge in the field is There is no doubt that specific actions have been proven to be essential to prevent the In order to support governmental bodies, healthcare professionals, and monitoring 110 systems, the WHO issued and updates periodically the Global Surveillance for human infection 111 with COVID-19 document (10), which includes case definitions for easy reference as described 112 in Table 1 . COVID-19 death is defined for surveillance purposes as a death resulting from a clinically compatible illness in a probable or confirmed COVID-19 case, unless there is a clear alternative cause of death that cannot be related to COVID disease (e.g.: trauma).
    keywords: case; contact; covid-19
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        item: #6659 of 7819
          id: cord-341527-03rh966o
      author: Stockton, John
       title: Dexmedetomidine and worsening hypoxemia in the setting of COVID-19: A case report
        date: 2020-05-27
       words: 1166
      flesch: 43
     summary: The pharmacokinetics of dexmedetomidine make it ideal in nonintubated COVID-19 patients. If dexmedetomidine can improve compliance with non-invasive oxygen support (the current recommended first-line therapy) while promoting better oxygenation, it may also decrease the need for mechanical ventilation and thus improve mortality.
    keywords: covid-19; dexmedetomidine; patient
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        item: #6660 of 7819
          id: cord-341529-dmiy0l9c
      author: Siniscalchi, Antonio
       title: Could COVID-19 represent a negative prognostic factor in patients with stroke?
        date: 2020-04-20
       words: 636
      flesch: 39
     summary: 4, 5 Several symptoms indicative of CNS involvement are present in approximately one-third of COVID-19 patients: dizziness, headache, impaired consciousness, ataxia, epilepsy, and acute cerebrovascular disease. 2,6 and in inflammatory biomarkers (eg, interleukin-6, C-reactive protein, and ferritin) 7 have been reported in COVID-19 patients.
    keywords: patients; stroke
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        item: #6661 of 7819
          id: cord-341543-gcnph9gf
      author: Kuryntseva, P.
       title: A simplified approach to monitoring the COVID-19 epidemiologic situation using waste water analysis and its application in Russia
        date: 2020-09-23
       words: 1833
      flesch: 41
     summary: The approach includes i) the creation of a calibration curve on the basis of the serial dilution of excreta collected from people who are infected with COVID-19 and ii) the analysis of wastewater samples and their serial dilutions but the approach excludes usage of concentration techniques before wastewater sample analysis as well as usage of external control in RT-PCR reactions for calculation of numbers of viral particles. In the present study, a modified approach for detection of COVID-19 infection rate using wastewater analysis has been developed.
    keywords: covid-19; preprint; testing; wastewater
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        item: #6662 of 7819
          id: cord-341574-6pmd04m9
      author: Weissman, Ruth S.
       title: IJED support for eating disorders research in the time of COVID‐19
        date: 2020-05-09
       words: 2350
      flesch: 44
     summary: key: cord-341574-6pmd04m9 authors: Weissman, Ruth S.; Klump, Kelly L.; Wade, Tracey; Thomas, Jennifer J.; Frank, Guido; Waller, Glenn title: IJED support for eating disorders research in the time of COVID‐19 date: 2020-05-09 journal: Int J Eat Disord DOI: 10.1002/eat.23293 sha: doc_id: 341574 cord_uid: 6pmd04m9 This editorial reports on an anonymous survey question posed to eating disorders researchers about changes the International Journal of Eating Disorders (IJED) should implement to support the eating disorders research community affected by COVID‐19. This editorial focuses on one facet: disruptions of eating disorders research.
    keywords: authors; covid-19; disorders; eating; ijed; research
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        item: #6663 of 7819
          id: cord-341575-8hv8rx6h
      author: Dhar, S. K.
       title: IL-6 and IL-10 as predictors of disease severity in COVID 19 patients: Results from Meta-analysis and Regression
        date: 2020-08-17
       words: 3819
      flesch: 43
     summary: Recently published meta-analysis studies on the levels of cytokines in COVID-19 patients have focussed mostly on IL-6 due to potential repurposing of tocilizumab to suppress the inflammatory condition. Multiple clinical studies have reported elevated levels of IL-10 in COVID-19 patients 2,15,16 .
    keywords: clinical; covid-19; il-10; il-6; medrxiv; patients; preprint; studies
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        item: #6664 of 7819
          id: cord-341577-txadxh13
      author: Santos García, D.
       title: Impact of COVID‐19 Pandemic on Parkinson´s Disease: A Cross‐sectional Survey of 568 Spanish Patients
        date: 2020-08-10
       words: 1582
      flesch: 52
     summary: When PD patients who had COVID-19 disease were compared with patients who did not have the infection, none of the patients who had COVID-19 had hallucinations compared with 23.4% of those who did not have the infection ( This article is protected by copyright. The main objective of the present study was to know how the COVID-19 pandemic has affected Spanish PD patients based on data from a sample of patients interviewed through an anonymous and voluntary online survey.
    keywords: covid-19; pandemic; patients
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        item: #6665 of 7819
          id: cord-341580-ymzlhsai
      author: Almskog, L.
       title: Rotational Thromboelastometry predicts care level in Covid-19
        date: 2020-06-12
       words: 3206
      flesch: 43
     summary: Results The ROTEM variables Maximum Clot Firmness (EXTEM-MCF and FIBTEM-MCF) were significantly higher in both groups of COVID-19 patients compared with healthy controls (p<0.001) and higher in severely ill patients compared with patients at regular wards (p<0.05). Coagulation Time (EXTEM-CT) was significantly longer and Clot Formation Time (EXTEM-CFT) significantly shorter in COVID-19 patients compared with healthy controls.
    keywords: clot; covid-19; extem; mcf; patients; preprint; rotem
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        item: #6666 of 7819
          id: cord-341620-nmrkhx5t
      author: Chirico, Francesco
       title: Can Air-Conditioning Systems Contribute to the Spread of SARS/MERS/COVID-19 Infection? Insights from a Rapid Review of the Literature
        date: 2020-08-20
       words: 4579
      flesch: 39
     summary: Revisiting the largest nosocomial severe acute respiratory syndrome outbreak in Hong Kong Role of air distribution in SARS transmission during the largest nosocomial outbreak in Hong Kong Evidence of airborne transmission of the severe acute respiratory syndrome virus Multi-zone modeling of probable SARS virus transmission by airflow between flats in Block E Extensive viable Middle East respiratory syndrome (MERS) coronavirus contamination in air and surrounding environment in MERS isolation wards Indoor transmission of SARS-CoV-2. The air exchange owing to temperature difference played a significant role in SARS transmission during the nosocomial outbreak in Ward 8A, and the two-way airflow effect at the openings could have played an important role in bioaerosol transmission
    keywords: air; conditioning; coronavirus; cov-2; covid-19; hvac; outbreak; sars; studies; systems; transmission
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        item: #6667 of 7819
          id: cord-341624-02bmonj6
      author: Liem, Andrian
       title: Ethical standards for telemental health must be maintained during the COVID-19 pandemic
        date: 2020-06-12
       words: 1238
      flesch: 44
     summary: An empirical investigation Technology use in mental health practice and research: Legal and ethical risks Telemedicine Practice Guidelines: Enabling Registered Medical Practitioners to Provide Healthcare Using Telemedicine Digital health applications in mental health care for immigrants and refugees: A rapid review Zoom, the video conferencing app everyone is using, faces questions over privacy The COVID-19 pandemic personal reflections on editorial responsibility. The use of technology in telemental health services is not only for curative purposes but also for assessment and monitoring as part of psychological first aid for the COVID-19 pandemic.
    keywords: clinicians; covid-19; health; patient
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        item: #6668 of 7819
          id: cord-341627-21m8rdhy
      author: Buda, Natalia
       title: Lung ultrasound in the diagnosis of COVID-19 infection - A case series and review of the literature
        date: 2020-06-25
       words: 2486
      flesch: 41
     summary: key: cord-341627-21m8rdhy authors: Buda, Natalia; Segura-Grau, Elena; Cylwik, Jolanta; Wełnicki, Marcin title: Lung ultrasound in the diagnosis of COVID-19 infection - Lung ultrasound (LUS) is a dynamically developing diagnostic method used in intensive care, cardiology and nephrology, it can also be helpful in diagnosing and monitoring pneumonia.
    keywords: coronavirus; covid-19; diagnosis; examination; lung; patients; ultrasound
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        item: #6669 of 7819
          id: cord-341644-egbahelm
      author: Benmarhnia, Tarik
       title: Linkages Between Air Pollution and the Health Burden from COVID-19: Methodological Challenges and Opportunities
        date: 2020-07-17
       words: 1978
      flesch: 18
     summary: Health Insurance, and the COVID-19 Recession Accurate statistics on COVID-19 are essential for policy guidance and decisions Long-term air pollution exposure and cardio-respiratory mortality: a review Respiratory health effects of air pollution: update on biomass smoke and traffic pollution Contribution of air pollution to COPD and small airway dysfunction Pulmonary health effects of air pollution Air pollution and respiratory viral infection COPD patients as vulnerable subpopulation for exposure to ambient air pollution Effect of outdoor air pollution on asthma exacerbations in children and adults: systematic review and multilevel meta-analysis Ambient particulate air pollution and acute lower respiratory infections: a systematic review and implications for estimating the global burden of disease PM 2.5 in Beijing-temporal pattern and its association with influenza Air pollution and case fatality of SARS in the People's Republic of China: an ecologic study Impact of long-term exposures to ambient PM2. In this commentary, methodological challenges and opportunities regarding the links between air pollution and COVID-19 are discussed with a focus on: i) the role of differential exposure to air pollution across populations and explain spatio-temporal variability of the epidemic spread and resultant mortality; ii) the indirect impacts of interventions treated as natural experiments to control COVID-19 person-to-person spread on air pollution and population health.
    keywords: air; covid-19; exposure; health; policies; pollution; target
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        item: #6670 of 7819
          id: cord-341650-f8orw6ro
      author: Li, Hailan
       title: Regarding “Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, single-blind, randomized controlled trial”
        date: 2020-09-17
       words: 512
      flesch: 42
     summary: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): a multicenter, singleblind, randomized controlled trial Risk factors associated with disease severity and length of hospital stay in COVID-19 patients Clinical characteristics and outcomes of hospitalised patients with COVID-19 treated in Hubei (epicentre) and outside Hubei (non-epicentre): a nationwide analysis of China A trial of lopinavir-ritonavir in adults hospitalized with severe covid-19 Temporal changes of CT findings in 90 patients with COVID-19 pneumonia: a longitudinal study Imaging features and evolution on CT in 100 COVID-19 pneumonia patients in Wuhan, China Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study key: cord-341650-f8orw6ro authors: Li, Hailan; Liu, Huaping title: Regarding “Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, single-blind, randomized controlled trial” date: 2020-09-17 journal: J Allergy Clin Immunol DOI: 10.1016/j.jaci.2020.09.002 sha: doc_id: 341650 cord_uid: f8orw6ro nan Regarding 'Ruxolitinib in Q 1 treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, singleblind, randomized controlled trial' Q 2 To the Editor:
    keywords: covid-19; ruxolitinib
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        item: #6671 of 7819
          id: cord-341661-sokoghh1
      author: Ahmed, Muhammad Adeel
       title: Fear and Practice Modifications among Dentists to Combat Novel Coronavirus Disease (COVID-19) Outbreak
        date: 2020-04-19
       words: 4620
      flesch: 45
     summary: Accordingly, 82% preferred asking about the patient's travel history, 81% recorded every patient's body temperature before performing dental treatments, and 78% deferred dental treatment of patients who disclosed suspicious symptoms. A number of dental practices have either modified their services according to the recommended guidelines to emergency treatment only or closed down practices for an uncertain period.
    keywords: covid-19; dental; dentists; fear; participants; patients; practice; study
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        item: #6672 of 7819
          id: cord-341674-q8p187qx
      author: Qiu, Jianyin
       title: A nationwide survey of psychological distress among Chinese people in the COVID-19 epidemic: implications and policy recommendations
        date: 2020-03-06
       words: 1559
      flesch: 44
     summary: Meanwhile, psychological distress levels were also influenced by availability of local medical resources, efficiency of the regional public health system, and prevention and control measures taken against the epidemic situation. key: cord-341674-q8p187qx authors: Qiu, Jianyin; Shen, Bin; Zhao, Min; Wang, Zhen; Xie, Bin; Xu, Yifeng title: A nationwide survey of psychological distress among Chinese people in the COVID-19 epidemic: implications and policy recommendations date: 2020-03-06 journal: Gen Psychiatr DOI: 10.1136/gpsych-2020-100213 sha: doc_id: 341674 cord_uid: q8p187qx The Coronavirus Disease 2019 (COVID-19) epidemic emerged in Wuhan, China, spread nationwide and then onto half a dozen other countries between December 2019 and early 2020.
    keywords: china; covid-19; distress; epidemic; health
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        item: #6673 of 7819
          id: cord-341684-buj8u63b
      author: Corbet, Shaen
       title: Any port in a storm: Cryptocurrency safe-havens during the COVID-19 pandemic
        date: 2020-07-07
       words: 1350
      flesch: 39
     summary: Chinese financial markets acted as the initial epicentre of the shock ), however, international contagion effects quickly escalated. We focus on larger cryptocurrency assets, those with a market value over $500 million 1 as of end January 2020.
    keywords: covid-19; cryptocurrencies; pandemic; sentiment
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        item: #6674 of 7819
          id: cord-341745-2txzi7kb
      author: Singh, S.
       title: Efficacy and Safety of Hydroxychloroquine and Chloroquine for COVID-19: A systematic review
        date: 2020-05-26
       words: 4773
      flesch: 45
     summary: CONCLUSIONS: Our systematic review of reported clinical studies did not identify substantial evidence to support the efficacy of hydroxychloroquine or chloroquine in hospitalized COVID-19 patients and raises questions about potential harm from QT prolongation and increased mortality. Our systematic review of reported clinical studies did not identify substantial evidence to support the efficacy of hydroxychloroquine or chloroquine in hospitalized COVID -19 patients and raises questions about potential harm from QT prolongation and increased mortality.
    keywords: covid-19; hydroxychloroquine; medrxiv; patients; preprint; review; studies
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        item: #6675 of 7819
          id: cord-341783-e7xz4utr
      author: Vistisen, Simon T.
       title: Risk and prognosis of COVID-19 in patients treated with renin–angiotensin–aldosterone inhibitors
        date: 2020-07-06
       words: 1908
      flesch: 40
     summary: Four studies examined the prognosis of COVID-19 patients and uniformly found that risk of severe outcomes was not higher for the collapsed group of ACEi and ARB 740 Vistisen et al. Inhibition of angiotensin-converting enzyme on the angiotensin II type 1 receptor by sartans (angiotensin II type 1 receptor blockers) leads to upregulation of angiotensin-converting enzyme 2. (ACE2) Angiotensin-converting enzyme 2 protects from severe acute lung failure Association of use of angiotensinconverting enzyme inhibitors and angiotensin II receptor blockers with testing positive for coronavirus disease 2019 (COVID-19) Renin-angiotensin-aldosterone system blockers and the risk of Covid-19 Renin-angiotensinaldosterone system inhibitors and risk of Covid-19 Use of renin-angiotensinaldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study Considerations for pharmacoepidemiological analyses in the SARS-CoV-2 pandemic Association of renin-angiotensin system inhibitors with severity or risk of death in patients with hypertension hospitalized for coronavirus disease 2019 (COVID-19) infection in Wuhan, China Drugs and the renin-angiotensin system in Covid-19 Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Assistance with the Editorial: none.
    keywords: acei; angiotensin; covid-19; patients; risk
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        item: #6676 of 7819
          id: cord-341804-rnj3wtg4
      author: Jin, Zhe
       title: Drug treatment of coronavirus disease 2019 (COVID-19) in China.
        date: 2020-06-27
       words: 2054
      flesch: 15
     summary: key: cord-341804-rnj3wtg4 authors: Jin, Zhe; Liu, Jing-Yi; Feng, Rang; Ji, Lu; Jin, Zi-Li; Li, Hai-Bo title: Drug treatment of coronavirus disease 2019 (COVID-19) in China. 7 authorization for the treatment of adults and children with severe COVID-19 disease 20 (Hendaus, 2020) .
    keywords: coronavirus; covid-19; disease; patients; treatment
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        item: #6677 of 7819
          id: cord-341806-7hatbzra
      author: Bone, Anna E
       title: Changing patterns of mortality during the COVID-19 pandemic: Population-based modelling to understand palliative care implications
        date: 2020-07-24
       words: 4211
      flesch: 53
     summary: We observe a 77% increase in home deaths between weeks 11 (n = 2725) and 17 (n = 4834), while care home deaths increased by 220% during the same period (week 11 n = 2471 and week 17 n = 7911). We estimate that 22% (13%–31%) of COVID-19 deaths occurred among people who might have been in their last year of life in the absence of the pandemic.
    keywords: care; covid-19; deaths; life; palliative; pandemic; people
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        item: #6678 of 7819
          id: cord-341814-poqni6ma
      author: Malin, Jakob J.
       title: DGI recommendations for COVID-19 pharmacotherapy
        date: 2020-10-19
       words: 808
      flesch: 45
     summary: [7] h Comparing the efficacy of a 5-day versus a 10-day course of remdesivir in patients with severe COVID-19 (SIMPLE SEVERE trial) a 10-day course was not superior to a 5-day treatment [8] i Reduced mortality at day 28 by one-third in patients with mechanical ventilation In a meta-evaluation of the SIMPLE (GS-US-540-5773) trial and retrospective cohort data, remdesivir treatment was associated with a 62% reduction of the odds ratio for mortality in patients with severe COVID-19
    keywords: covid-19; patients; remdesivir
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        item: #6679 of 7819
          id: cord-341818-mm3d4jkh
      author: Ying, Mingliang
       title: COVID-19 with acute cholecystitis: a case report
        date: 2020-06-22
       words: 1713
      flesch: 52
     summary: PTGD is useful for acute cholecystitis in COVID-19 patients. It was difficult to identify the cause of acute cholecystitis in COVID-19 patients by abdominal CT imaging.
    keywords: acute; cholecystitis; covid-19; gallbladder
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        item: #6680 of 7819
          id: cord-341833-wf72fra8
      author: Liu, Guoqiang
       title: A Single Large Dose of Vitamin D Could be Used as a Means of Coronavirus Disease 2019 Prevention and Treatment
        date: 2020-08-21
       words: 2569
      flesch: 42
     summary: It has been shown that low Vit D level is associated with viral infection, and Vit D supplementation is beneficial for people infected with viruses, such as HIV and hepatitis C virus. 17 There is strong evidence that low Vit D level is associated with viral infection and Vit D supplementation is beneficial for people receiving antiviral therapy.
    keywords: covid-19; deficiency; patients; vit; vitamin
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        item: #6681 of 7819
          id: cord-341837-jmbbgfsz
      author: Patel, Pratit
       title: “COVID-19 and cervical artery dissection- A causative association?”
        date: 2020-06-13
       words: 1641
      flesch: 40
     summary: The management of COVID-19 patients with arterial dissection should continue to be dictated by the clinical examination and imaging studies. Head and neck imaging could also be considered in COVID-19 patients who present with unusual and unremitting headaches especially those Clinical features of COVID-19 in elderly patients: A comparison with young and middle-aged patients Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Comorbidities and multi-organ injuries in the treatment of COVID-19 Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young Incidence of thrombotic complications in critically ill ICU patients with COVID-19 COVID-19 and stroke-A global World Stroke Organization perspective Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019:
    keywords: artery; covid-19; dissection; patients
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        item: #6682 of 7819
          id: cord-341868-btalafo6
      author: Carlet, Jean
       title: Steroids for sepsis and ARDS: this eternal controversy remains with COVID-19
        date: 2020-10-09
       words: 556
      flesch: 58
     summary: Many sepsologists push very hard and without any doubt to include Covid-19 severe cases in the sepsis syndrome. In addition, secondary infections with nosocomial pathogens are very frequent in severe COVID-19 disease, making the prognosis even more complex to evaluate.
    keywords: covid-19; sepsis
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        item: #6683 of 7819
          id: cord-341880-wxliz485
      author: Mottaleb, Khondoker Abdul
       title: COVID-19 induced economic loss and ensuring food security for vulnerable groups: Policy implications from Bangladesh
        date: 2020-10-16
       words: 7554
      flesch: 57
     summary: By multiplying the estimated per head average daily wage earnings (in BDT) in the farm sector W f and that in the nonfarm sector W nf by the absolute number of daily waged workers in those in Bangladesh, the expected loss of daily wage earnings due to the COVID-19 induced lockdown is calculated as follows: To estimate the minimum compensation package for the daily wage-based workers to ensure the minimum food security, we specify and estimate a function that explains household level daily food expenditure for the household of daily wage worker i (that is, survey respondent i) in sector s, as follows: where lnEDFX is the natural log of the household level daily total expenditure on all food (in terms of BDT); wage earnings, lnDWEH is is the natural log of the total daily wage earning of the household of respondent i calculated as: The definitions of the vectors of variables ILC is and RLC is are the same as explained in Eq (1). It provides the share of total wage earnings are spent on household level daily food expenditure of a sampled day-labor household in farm and nonfarm sectors.
    keywords: bangladesh; covid-19; expenditure; farm; food; household; level; lockdown; nonfarm; table; total; wage; workers
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        item: #6684 of 7819
          id: cord-341919-8gnthufw
      author: Basi, Saajan
       title: Clinical course of a 66-year-old man with an acute ischaemic stroke in the setting of a COVID-19 infection
        date: 2020-08-23
       words: 4197
      flesch: 45
     summary: As of April 2020, no comprehensive data of the relationship between ischaemic stroke and COVID-19 has been published, however early retrospective case series from three hospitals in Wuhan, China have indicated that up to 36% of COVID-19 patients had neurological manifestations, including stroke. 13 Other hypothesised reasons for stroke development in COVID-19 patients are the development of hypercoagulability, as a result of critical illness or new onset of arrhythmias, caused by severe infection.
    keywords: admission; care; covid-19; oxygen; patient; pneumonia; sars; stroke
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        item: #6685 of 7819
          id: cord-341948-9w8od50e
      author: Scott, Michael
       title: Rare encounter: hydrocoele of canal of Nuck in a Scottish rural hospital during the COVID-19 pandemic
        date: 2020-08-11
       words: 2747
      flesch: 40
     summary: 1 5 15 16 The most frequent sign of Nuck hydrocoele is inguinolabial lump or swelling, rendering it clinically indistinguishable from inguinal hernia. When encysted, or associated with infection or endometriosis, the swelling is severely painful and incarcerated inguinal hernia will be the primary differential diagnosis.
    keywords: canal; covid-19; hernia; hospital; hydrocoele; nuck; patient
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        item: #6686 of 7819
          id: cord-341976-yts6pzn3
      author: Liu, Xintian
       title: Serum IgM against SARS-CoV-2 correlates with in-hospital mortality in severe/critical patients with COVID-19 in Wuhan, China
        date: 2020-07-06
       words: 3070
      flesch: 52
     summary: Although patients admitted into ICU required more medical treatments, the effect of advanced support seemed to be controversial in critical patients [31, 32] . Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore The epidemiology and clinical information about COVID-19 Covid-19 in critically ill patients in the seattle region -case series Profile of Specific Antibodies to SARS-CoV-2: The First Report Longitudinal profile of antibodies against SARS-coronavirus in SARS patients and their clinical significance Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes Positive RT-PCR test results in patients recovered from COVID-19 Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China Real-time estimation of the risk of death from novel coronavirus (COVID-19) infection: inference using exported cases Therapeutic options for the 2019 novel coronavirus (2019-nCoV)
    keywords: coronavirus; covid-19; disease; igm; patients; study; titer
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        item: #6687 of 7819
          id: cord-341982-0i1w137u
      author: Barral, Matthias
       title: Bronchial Artery Embolization Performed in COVID-19 Patients: Tolerance and Outcomes
        date: 2020-08-26
       words: 853
      flesch: 45
     summary: COVID-19 patients followed a specific pathway including a dedicated intensive care unit (ICU) and elevator. Of all, 71% of BAE was performed under general anesthesia for COVID-19 patients, and none in the non-COVID-19 group (p \ 0.01, Chi-square test).
    keywords: bae; covid-19; patients
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        item: #6688 of 7819
          id: cord-341987-lsvifqyo
      author: Kalyanasundaram, Sridhar
       title: Novel Corona Virus Pandemic and Neonatal Care: It’s Too Early to Speculate on Impact!
        date: 2020-08-03
       words: 3969
      flesch: 48
     summary: Children are less susceptible to COVID-19 infection and generally have a mild course. Children are less susceptible to COVID-19 infection and generally have a mild course in newborns, and children experience with significantly lower death rates [3, 4] .
    keywords: baby; coronavirus; covid-19; infection; mother; neonatal; sars; women
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        item: #6689 of 7819
          id: cord-342013-k54u2q0d
      author: Martenot, Antoine
       title: Favorable outcomes among neonates not separated from their symptomatic SARS-CoV-2-infected mothers
        date: 2020-11-03
       words: 1950
      flesch: 48
     summary: These results are in accordance with the very low incidence of infection in newborns of infected mothers in a national cohort of the United Kingdom, in which guidelines for the postnatal management of infants of infected mothers included keeping the mother and infant together and encouraging breastfeeding with strict infection control measures from birth. The impact of this approach should also be evaluated in preterm infants born to infected mothers.
    keywords: cov-2; covid-19; mothers; neonates; sars
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        item: #6690 of 7819
          id: cord-342041-x0bwjl54
      author: Vivien, Benoît
       title: Adaptation de la Régulation Médicale du SAMU face à la pandémie du COVID-19
        date: 2020-09-01
       words: 4101
      flesch: 45
     summary: Dernier élément important, à l'instar des observatoires surveillant les épidémies par l'intermédiaire de l'activité de la médecine de ville par exemple, il s'est avéré que le nombre d'appels au SAMU de patients graves a précédé d'environ deux semaines la saturation des lits de réanimation. A titre d'exemple, au SAMU 75, des pédiatres hospitaliers sont venus renforcer la régulation médicale pédiatrique, dont l'activité a été majorée de manière importante, même si cette augmentation était bien moindre que celle observée au niveau de la régulation « adulte ».
    keywords: crra; dans; des; les; médecins; médicale; pour; que; régulation; samu; une; été
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        item: #6691 of 7819
          id: cord-342059-y3zlyy1z
      author: von der Thüsen, Jan H.
       title: Case report: a fatal combination of hemophagocytic lymphohistiocytosis with extensive pulmonary microvascular damage in COVID-19 pneumonia
        date: 2020-10-23
       words: 1942
      flesch: 30
     summary: The role of cytokines including interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease Remdesivir for the treatment of Covid-19 -preliminary report Dexamethasone in hospitalized patients with Covid-19 -preliminary report Cytokine release syndrome in severe COVID-19 Rheumatologists' perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets Continuous intravenous anakinra infusion to calm the cytokine storm in macrophage activation syndrome Favorable anakinra responses in severe COVID-19 patients with secondary hemophagocytic lymphohistiocytosis Tocilizumab in patients with severe COVID19: a retrospective cohort study Development and validation of the HScore, a score for the diagnosis of reactive Hemophagocytic syndrome Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19 Simultaneous presence of hypercoagulation and increased clot Lysis time due to IL-1β, IL-6 and IL-8 COVID-19: the vasculature unleashed Secondary HLH is uncommon in severe COVID-19 COVID-19: consider cytokine storm syndromes and immunosuppression Effect of dexamethasone in hospitalized patients with COVID-19: preliminary report Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Acknowledgments Here we present a case with histopathological evidence for hemophagocytic lymphohistiocytosis (HLH) and extensive concurrent microvascular damage in fatal COVID-19 pneumonia and speculate on the cooccurrence of these serious complications of SARS-CoV-2 infection.
    keywords: covid-19; cytokine; disease; hlh; pneumonia
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        item: #6692 of 7819
          id: cord-342096-pijvvo2i
      author: Peivandi, S.
       title: Evaluation of attitude among infertile couples about continuing assisted reproductive technologies therapy during novel coronavirus outbreak
        date: 2020-09-03
       words: 3789
      flesch: 45
     summary: Therefore, it is suspected that SARS-CoV-2 could be transmitted through sexual secretions (7) , and such concerns about infectious diseases can affect the process of continuing infertility treatment in infertile couples (11, 12) . Also, it has been reported that some viral infectious diseases such as Zika can cause abnormalities and microcephaly in the fetus (26) , which has influenced the attitude and decision of infertile couples to continue infertility treatment with ART (26, 27) .
    keywords: couples; covid-19; infertility; license; preprint; study; treatment
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        item: #6693 of 7819
          id: cord-342108-5xd68rie
      author: Warne, D. J.
       title: Hindsight is 2020 vision: Characterisation of the global response to the COVID-19 pandemic
        date: 2020-05-05
       words: 6835
      flesch: 53
     summary: The effective management of COVID-19 cases within Germany can be inferred by a low value for the relative case fatality rate δ/β = 0.083 (95% CI Daily counts of reported confirmed COVID-19 cases, recoveries and deaths for each country are obtained from the Johns Hopkins University coronavirus resource center (coronavirus.jhu.edu/;
    keywords: cases; countries; covid-19; fig; model; r t; rate; transmission
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        item: #6694 of 7819
          id: cord-342121-ff4fpsq8
      author: Miller, Eric D.
       title: Loneliness in the Era of COVID-19
        date: 2020-09-18
       words: 1445
      flesch: 41
     summary: A Biography of Loneliness: The History of an Emotion 15 smartphone apps for older adults to use while in isolation during the COVID-19 pandemic Alarming trends in US domestic violence during the COVID-19 pandemic Keep socially (but not physically) connected and carry on: Preventing suicide in the age of COVID-19 The mental health consequences of COVID-19 and physical distancing: the need for prevention and early intervention The lonely city: urban infrastructure and the problem of loneliness Effects of social grooming on incivility in COVID-19 The effect of COVID-19 on youth mental health Age differences in loneliness from late adolescence to oldest old age The COVID-19 pandemic crisis: the loss and trauma event of our time Dyadic perspectives on marital quality and loneliness in later life Connectedness to nature is more strongly related to connection to distant, rather than close, others The Psychological Journey to and From Loneliness: Development, Causes, and Effects of Social and Emotional Isolation Is loneliness the same as being alone? Loneliness, isolation, and social support factors in post-COVID-19 mental health Loneliness: an integrative approach COVID-19, fear and the future: an attachment perspective Ang, Y. Y. (2020) .
    keywords: covid-19; crisis; loneliness; pandemic
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        item: #6695 of 7819
          id: cord-342129-74yqqocc
      author: Najafi, Farid
       title: Serial interval and time-varying reproduction number estimation for COVID-19 in West of Iran
        date: 2020-06-14
       words: 2469
      flesch: 47
     summary: For this purpose, different serial interval applied to show how reproduction number changed with various serial interval. In the EpiEstim package, estimation of reproduction number by time-varying method can be done by various approaches for serial interval which are non-parametric, parametric, uncertain serial interval, serial interval from data and serial interval from sample.
    keywords: cases; covid-19; interval; number; time
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        item: #6696 of 7819
          id: cord-342139-t2tukk0z
      author: Livingston, Gill
       title: Prevalence, management, and outcomes of SARS-CoV-2 infections in older people and those with dementia in mental health wards in London, UK: a retrospective observational study
        date: 2020-10-05
       words: 6642
      flesch: 50
     summary: Implementation of the long-standing policy of parity of esteem for mental health so that resources are as available to mental health patients is urgently needed. In some Trusts, resources to protect mental health patients and staff were unavailable at the time they became available for those admitted locally with physical illness, with patients in intensive care units being tested from March 3, 2020, 32 and symptomatic patients in general hospital wards being tested before March 28, 2020.
    keywords: care; cov-2; covid-19; dementia; health; mental; patients; people; sars; study; trusts
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        item: #6697 of 7819
          id: cord-342143-un14oynk
      author: Fernández-Díaz, Eva
       title: COVID-19 and multiple sclerosis: A description of two cases on alemtuzumab
        date: 2020-07-17
       words: 1618
      flesch: 47
     summary: For that, we aim to share our experience about COVID-19 in MS patients treated with alemtuzumab, one of them in the first week after dosing. In selected patients (young, without comorbidities, and with high activity), MS itself could be more dangerous than COVID-19, so we should consider continuing MS treatment as previously planned, including alemtuzumab.
    keywords: alemtuzumab; covid-19; infection; sars
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        item: #6698 of 7819
          id: cord-342156-4c8rzo62
      author: Hung, Orlando
       title: Personal protective equipment during the COVID-19 pandemic (Letter #2)
        date: 2020-08-10
       words: 948
      flesch: 45
     summary: While it is helpful to use the size of viral-laden droplets (greater or smaller than 5 lm) as an index of transmissibility for infection control measures, it is also important for healthcare workers (HCWs) to take into consideration the complex dynamic nature and the site of deposition of infected droplets, and the critical pathogen load of droplets required for establishing infection in different airway regions. To summarize, transmission of the infection can occur only if viral droplets land on the exposed skin or objects in the environment (fomites), subsequently contaminating the hands, which then may deposit viral droplets on eyes, nose, or mouth.
    keywords: covid-19; droplets; hcws
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        item: #6699 of 7819
          id: cord-342185-2umby2l8
      author: Cai, Qi
       title: The mental health of frontline and non-frontline medical workers during the coronavirus disease 2019 (COVID-19) outbreak in China: a case-control study
        date: 2020-07-02
       words: 4044
      flesch: 39
     summary: Univariate and multivariate logistic regressions were performed to evaluate the relationships of frontline medical workers (vs. non-frontline medical workers) with mental problems, and help-seeking behaviors and treatment for mental problems. However, frontline medical workers had a higher proportion of medical staff (mainly including doctors and nurses) than non-frontline medical workers (98.6% vs. 93.4%, P < 0.01).
    keywords: covid-19; frontline; health; outbreak; problems; study; workers
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        item: #6700 of 7819
          id: cord-342204-9tgxijvn
      author: Nuzzo, Domenico
       title: Potential neurological effects of severe COVID-19 infection
        date: 2020-07-03
       words: 3228
      flesch: 32
     summary: When a virus proliferates in tissue cells of lung this leads to alveolar gas exchange disorders causing hypoxia in the CNS, increasing anaerobic metabolism in the mitochondria of brain cells (Di Carlo et al., 2012; Hypoxia can cause cerebral vasodilation, swelling of brain cells, interstitial edema, cerebral blood flow obstruction, ischemia, and congestion .
    keywords: brain; cov-2; covid-19; patients; sars; stress; virus
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        item: #6701 of 7819
          id: cord-342206-mitfgsdo
      author: Asif, Talal
       title: Transient ST Segment Elevation in Two Patients with COVID-19 and a Normal Transthoracic Echocardiogram
        date: 2020-04-23
       words: 954
      flesch: 45
     summary: The variety of cardiovascular presentations of COVID-19 Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China Coronavirus fulminant myocarditis saved with glucocorticoid and human immunoglobulin Cardiac involvement in a patient with coronavirus disease 2019 (COVID-19) Characteristic ECG manifestations in patients with COVID-19 Catheterization laboratory considerations during the coronavirus (COVID-19) pandemic: from ACC's Interventional Council and SCAI Spontaneous coronary artery dissection in a patient with COVID-19 DISCUSSION We describe two cases of transient ST elevation on ECG in patients with normal left ventricular (LV) function and COVID-19. These cases add to our understanding of cardiac involvement in active COVID-19, especially given the uncertainty in proceeding with invasive coronary angiography and the need to balance staff exposure with patient benefit Acute coronary syndrome type 1 also remains a possibility given the systemic proinflammatory stimulation and hypercoagulability in patients with acute COVID-19
    keywords: covid-19; patient
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        item: #6702 of 7819
          id: cord-342216-xus2ckrc
      author: Sánchez-Duque, Jorge A.
       title: Enfermedad por Coronavirus 2019 (COVID-19) en América Latina: Papel de la atención primaria en la preparación y respuesta
        date: 2020-04-17
       words: 753
      flesch: 28
     summary: key: cord-342216-xus2ckrc authors: Sánchez-Duque, Jorge A.; Arce-Villalobos, Laura R.; Rodríguez-Morales, Alfonso J. title: Enfermedad por Coronavirus 2019 (COVID-19) en América Latina: Papel de la atención primaria en la preparación y respuesta date: 2020-04-17 journal: Aten Primaria DOI: 10.1016/j.aprim.2020.04.001 sha: doc_id: 342216 cord_uid: xus2ckrc nan J o u r n a l P r e -p r o o f 3 a los sistemas de salud, por ello, deben estar vinculados en la planificación de conductas ante posibles brotes, así como, recibir entrenamiento para fortalecer sus fases de prevención, preparación, respuesta y recuperación 1, 2, 8 . Según reportes, cerca del 57% de los países del mundo tienen la capacidad de responder ante eventos infecciosos emergentes, sin embargo, como se ha evidenciado con COVID-19, este porcentaje parece ser mucho menor 2,6 .
    keywords: covid-19; los; por
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        item: #6703 of 7819
          id: cord-342225-lcaemapt
      author: Wang, Chuanbin
       title: Initial CT features and dynamic evolution of early-stage patients with COVID-19
        date: 2020-08-23
       words: 2551
      flesch: 44
     summary: key: cord-342225-lcaemapt authors: Wang, Chuanbin; Shi, Bin; Wei, Chao; Ding, Huaming; GU, Jinfeng; Dong, Jiangning title: Initial CT features and dynamic evolution of early-stage patients with COVID-19 date: 2020-08-23 journal: Radiol Infect Dis DOI: 10.1016/j.jrid.2020.08.002 sha: doc_id: 342225 cord_uid: lcaemapt Abstract Objective To explore the initial CT features and dynamic evolution of early-stage patients with Coronavirus disease 2019 (COVID-19). Initial CT features of early-stage patients with COVID-19 (Table 2) Lesion distribution: ① unilateral in 14 (11.1%) and bilateral in 112 ⑤ the main accompanying CT features with a proportion of more than 50%: vascular thickening sign in 98 (77.8%) (Fig 1.
    keywords: covid-19; disease; sign
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        item: #6704 of 7819
          id: cord-342231-862kffnb
      author: Carneiro, Thiago
       title: Intravenous tPA for Acute Ischemic Stroke in Patients with COVID-19
        date: 2020-07-27
       words: 1859
      flesch: 44
     summary: key: cord-342231-862kffnb authors: Carneiro, Thiago; Dashkoff, Jonathan; Leung, Lester Y.; Nobleza, Christa O'Hana S.; Marulanda-Londono, Erika; Hathidara, Mausaminben; Koch, Sebastian; Sur, Nicole; Boske, Alexandra; Voetsch, Barbara; Nour, Hassan Aboul; Miller, Daniel J; Daneshmand, Ali; Shulman, Julie; Curiale, Gioacchino; Greer, David M.; Romero, Jose Rafael; Anand, Pria; Cervantes-Arslanian, Anna M. title: Intravenous tPA for Acute Ischemic Stroke in Patients with COVID-19 date: 2020-07-27 journal: J Stroke Cerebrovasc Dis DOI: 10.1016/j.jstrokecerebrovasdis.2020.105201 sha: doc_id: 342231 cord_uid: 862kffnb Background/Purpose: Coronavirus disease 2019 (COVID-19) is associated with increased risk of acute ischemic stroke (AIS), however, there is a paucity of data regarding outcomes after administration of intravenous tissue plasminogen activator (IV tPA) for stroke in patients with COVID-19. In spite of the uncertain hematologic effects of COVID-19, our findings suggest that IV tPA may be used safely in acute ischemic stroke patients with COVID-19 and is associated with improved outcomes.
    keywords: acute; covid-19; patients; stroke; tpa
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        item: #6705 of 7819
          id: cord-342241-76mtn1m7
      author: Lenti, Marco Vincenzo
       title: Carving out a place for internal medicine during COVID‐19 epidemic in Italy
        date: 2020-05-04
       words: 1274
      flesch: 40
     summary: In summary, internal medicine has responded promptly to COVID-19 Italian epidemic, due to its holistic attitudethe sick patient as an individual, rather than the disease, is the object of the studyand its methodological approach [5] . The first few COVID-19 cases were suspected and diagnosed in internal medicine wards, including, among others, a young adult male from Codogno (referred to as patient 1), who was later transferred to the Intensive Care Unit of our hospital.
    keywords: covid-19; disease; medicine; patients
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        item: #6706 of 7819
          id: cord-342246-tnjtd9n3
      author: Özçelik Korkmaz, Müge
       title: Otolaryngological manifestations of hospitalised patients with confirmed COVID-19 infection
        date: 2020-10-03
       words: 4427
      flesch: 48
     summary: Hyposmia can generally be caused by upper respiratory tract infections; however, these symptoms can be present in COVID-19 patients without any nasal symptoms, suggesting the direct viral damage to the chemosensory system [9] . These datas suggest that otological and vestibular symptoms should also be questioned in COVID-19 patients.
    keywords: clinical; covid-19; patients; smell; study; symptoms; taste; terms
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        item: #6707 of 7819
          id: cord-342294-x18xmrji
      author: Yan, Nao
       title: Medium Term Follow-Up of 337 Patients With Coronavirus Disease 2019 (COVID-19) in a Fangcang Shelter Hospital in Wuhan, China
        date: 2020-07-03
       words: 2709
      flesch: 41
     summary: However, information regarding post-discharge quarantine and surveillance of recovered patients with COVID-19 is scarce. However, information regarding clinical manifestations and discharge surveillance of recovered patients is scarce.
    keywords: acid; covid-19; discharge; nucleic; patients; quarantine
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        item: #6708 of 7819
          id: cord-342303-ddulfe06
      author: Ismael, Julia
       title: Multidisciplinary approach to COVID-19 and cancer: consensus from scientific societies in Argentina
        date: 2020-05-13
       words: 7129
      flesch: 39
     summary: Cancer patients are a very special population in this setting since they are more susceptible to viral infections than the general population. To review the evidence available in order to create a multi-institutional position from the perspective of scientific societies in Argentina involved in the management of cancer patients.
    keywords: cancer; cancer patients; care; cases; covid-19; health; infection; palliative; pandemic; panel; patients; recommendations; risk; therapy; treatment
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        item: #6709 of 7819
          id: cord-342324-it6zcyht
      author: Dhaliwal, Ruban
       title: Letter to the Editor: “Our Response to COVID-19 as Endocrinologists and Diabetologists”
        date: 2020-05-08
       words: 685
      flesch: 36
     summary: Thus, there is a need for close monitoring of serum calcium levels in symptomatic COVID patients, and adherence with calcitriol and calcium supplements as prescribed and follow sick-day guidelines (4). Second area of concern is the potential for interruption of parenteral treatments in patients with osteoporosis during this pandemic, many of whom are in the high-risk group for COVID-19 infection because of advanced age and/or comorbidities.
    keywords: covid-19
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        item: #6710 of 7819
          id: cord-342338-nxfg9yfq
      author: Montero, A.
       title: Low-dose radiation therapy: could it be a game-changer for COVID-19?
        date: 2020-05-25
       words: 2324
      flesch: 37
     summary: It is at the beginning of the proinflammatory phase that the use of anti-inflammatory treatments such as corticosteroids and cytokine inhibitors tocilizumab (IL-6 inhibitor) or anakinra (IL-1 receptor antagonist) seems to be justified. Unlike high-dose radiation therapy that induces the production of proinflammatory cytokines in immune and endothelial cells, paradoxically LD-RT (0.5-1.5 Gy) acts on cells involved in the inflammatory response, producing anti-inflammatory effects.
    keywords: covid-19; dose; patients; treatment
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        item: #6711 of 7819
          id: cord-342340-q6j7vy8u
      author: Jefferies, Sarah
       title: COVID-19 in New Zealand and the impact of the national response: a descriptive epidemiological study
        date: 2020-10-14
       words: 5727
      flesch: 39
     summary: We use highly complete, prospectively collected national COVID-19 case and testing datasets to comprehensively describe New Zealand's initial public health response to COVID-19. Characteristics of cases with severe disease outcomes (hospitalisation or death) were compared with non-severe cases.
    keywords: cases; covid-19; data; health; new; people; phase; population; response; study; testing; zealand
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        item: #6712 of 7819
          id: cord-342360-d7qc20i4
      author: Mohamad, Siti Mazidah
       title: Creative Production of ‘COVID‐19 Social Distancing’ Narratives on Social Media
        date: 2020-06-03
       words: 6075
      flesch: 32
     summary: Using qualitative content analysis (QCA) data of social media content by Bruneian youth, this paper reveals the localised and contextualised creative production of five ‘social distancing’ narratives as a response to the national and global concerns in times of a global pandemic: narrative of fear; narrative of responsibility; narrative of annoyance; narrative of fun; and narrative of resistance. The growth in the size of the digitally connected group consuming social media content in the nation justifies this interest in looking into social media use in risk communication in Brunei Darussalam.
    keywords: communication; country; covid-19; distancing; health; media; narrative; people; public; risk; youth
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        item: #6713 of 7819
          id: cord-342361-eu3rry7p
      author: Lu, Jiatao
       title: ACP risk grade: a simple mortality index for patients with confirmed or suspected severe acute respiratory syndrome coronavirus 2 disease (COVID-19) during the early stage of outbreak in Wuhan, China
        date: 2020-02-23
       words: 3792
      flesch: 46
     summary: We aimed to characterize the clinical features of hospitalized patients with confirmed or suspected COVID-19, and develop a mortality risk index for COVID-19 patients. We aimed to characterize the clinical features of hospitalized patients with confirmed or suspected COVID-19, and develop a mortality risk index for COVID-19 patients.
    keywords: covid-19; funder; license; medrxiv; patients; preprint
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        item: #6714 of 7819
          id: cord-342362-j7vuoer6
      author: Gegúndez-Fernández, José A
       title: Recomendaciones para la atención oftalmológica durante el estado de alarma por la pandemia de enfermedad por coronavirus COVID-19
        date: 2020-04-25
       words: 3526
      flesch: 36
     summary: [22] [23] Así, el Ministerio de Sanidad ha elaborado un protocolo para el manejo y tratamiento de los pacientes con infección por SARS-CoV-2, que se actualiza permanentemente, en el que recomiendan el uso de la cloroquina base para adultos y de la hidroxicloroquina sulfato para adultos y pacientes pediátricos durante 5 días con una dosis de carga el primer día. Informe V1/23052013 de la Agencia Española de Medicamentos y Productos Sanitarios sobre el uso de Plasma Rico en Plaquetas Real Decreto 1088/2005, de 16 de septiembre, por el que se establecen los requisitos técnicos y condiciones mínimas de la hemodonación y de los centros y servicios de transfusión Tratamientos disponibles para el manejo de la infección respiratoria por SARS-CoV-2 A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial The Royal College of Ophthalmologists recommendations on screening for hydroxychloroquine and chloroquine users in the United Kingdom: executive summary Ophthalmology.
    keywords: caso; como; con; contacto; coronavirus; cov-2; covid-19; del; durante; infección; las; los; pacientes; pandemia; para; por; posible; que; sars; ser; sobre; síntomas; tratamiento; una; uso
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        item: #6715 of 7819
          id: cord-342386-t5b8wpe2
      author: Falcone, Rino
       title: All We Need Is Trust: How the COVID-19 Outbreak Reconfigured Trust in Italian Public Institutions
        date: 2020-10-02
       words: 14134
      flesch: 15
     summary: Thus, assuming that the need for public trust prompted the high levels of institutional trust manifested by participants, we propose to interpret their other responses within the broad framework of motivated reasoning (Kunda, 1990) and cognitive dissonance theory (Festinger, 1957) : as the chosen path to pursue the paramount goal of personal and public safety, trusting public authorities became in turn a necessary instrumental goal, thus coloring all other attitudes expressed by the respondents; more precisely, it prompted them to actively look for reasons to justify their (unavoidable) trust in public authorities, in order to minimize cognitive dissonance. Expectations on the impact of trust toward public institutions and among citizens are less triumphant, yet still positive: 54.4% predict an increase in institutional trust after the COVID-19 pandemic, whereas 57% make the same prediction with respect to social trust, i.e., trust among peers.
    keywords: authorities; citizens; covid-19; crisis; data; institutions; item; measures; pandemic; public; respondents; survey; trust
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        item: #6716 of 7819
          id: cord-342418-57cu4oeu
      author: Mol, B. W.
       title: Strict lockdown versus flexible social distance strategy for COVID-19 disease: a cost-effectiveness analysis
        date: 2020-09-18
       words: 3656
      flesch: 51
     summary: key: cord-342418-57cu4oeu authors: Mol, B. W.; Karnon, J. title: Strict lockdown versus flexible social distance strategy for COVID-19 disease: a cost-effectiveness analysis date: 2020-09-18 journal: nan DOI: 10.1101/2020.09.14.20194605 sha: doc_id: 342418 cord_uid: 57cu4oeu Objectives To balance the costs and effects comparing a strict lockdown versus a flexible social distancing strategy for societies affected by Coronavirus-19 Disease (COVID-19). The incremental costs of strict lockdown to save one life year was US$ 137,285, and higher in most of the sensitivity analyses.
    keywords: covid-19; life; lockdown; medrxiv; preprint; sweden; years
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        item: #6717 of 7819
          id: cord-342459-aroutcgh
      author: Feldman, Hope A.
       title: Commentary: Remote Learning Creates More Room at the Table
        date: 2020-08-06
       words: 667
      flesch: 50
     summary: In this Expert Opinion, Dr. Vervoot and colleagues discuss the many benefits to be 20 gained from the increased utilization of online platforms for surgical education and conferences 1 . Continuing surgical education during this unprecedented time-a time in which maintaining an 22 adequate physical distance from others has been prioritized-has posed a number of newchallenges.
    keywords: covid-19; education
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        item: #6718 of 7819
          id: cord-342467-3se4s217
      author: Parikh, Keval D.
       title: Quantifying the decrease in emergency department imaging utilization during the COVID-19 pandemic at a multicenter healthcare system in Ohio
        date: 2020-09-01
       words: 4384
      flesch: 55
     summary: A retrospective observational study was conducted assessing ED imaging volumes between March 1, 2020, and May 11, 2020, during the COVID-19 crisis. Predictive models and anecdotal articles suggest ED imaging volumes have declined by around 50%; however, minimal actual data has been published to substantiate these figures [4] [5] [6] .
    keywords: chest; covid-19; exams; imaging; volume
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        item: #6719 of 7819
          id: cord-342498-f93jma3d
      author: Srivastava, A.
       title: Geographical Variation in COVID-19 Cases, Prevalence, Recovery and Fatality Rate by Phase of National Lockdown in India, March 14-May 29, 2020
        date: 2020-06-05
       words: 4976
      flesch: 55
     summary: There is an exponential increase in COVID-19 cases both at national and sub-national levels. At state-level, the maximum number of COVID-19 cases is found in the states of Maharashtra, Tamil Nadu, Delhi, and Gujarat contributing 66.75 percent of total cases.
    keywords: cases; covid-19; license; lockdown; medrxiv; percent; preprint; rate
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        item: #6720 of 7819
          id: cord-342517-bzmhjvr5
      author: Rassouli, Maryam
       title: COVID-19 Management in Iran as One of the Most Affected Countries in the World: Advantages and Weaknesses
        date: 2020-09-15
       words: 2283
      flesch: 36
     summary: The launch of MOHME online patient screening system for screening more than 75 million people so far and controlling the outbreak was among the effective measures taken to reduce referrals to health centers and reduce the risk of infection in healthy people, of which 146,000 were discovered and referred to health centers (10) . One of the best strategies is to use the experiences of other countries in dealing with COVID-19.
    keywords: countries; country; covid-19; health; iran; system
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        item: #6721 of 7819
          id: cord-342523-52t7dh4n
      author: Dibner, Julia J.
       title: Direct COVID-19 Infection of Enterocytes: The Role of Hypochlorhydria
        date: 2020-08-11
       words: 1303
      flesch: 41
     summary: Acquired H. pylori infection and the use of proton pump inhibitors (PPI) are also associated with low stomach acid (7), as is stress (8). COVID-19 virus may not survive normal gastric acid If COVID-19 virus can resist the pH levels of 3-5 typical of hypochlorhydria, it would have a route from mouth to intestine, where the virus could directly infect ACE2-bearing enterocytes there (1).
    keywords: covid-19; fecal; transmission
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        item: #6722 of 7819
          id: cord-342555-5r9aa7u5
      author: Eghtesadi, Marzieh
       title: Breaking Social Isolation Amidst COVID‐19: A Viewpoint on Improving Access to Technology in Long‐Term Care Facilities
        date: 2020-04-24
       words: 1607
      flesch: 35
     summary: For older patients isolated in LTC facilities, providing them with these technology-dependent amenities and social contacts could potentially decrease their sense of loneliness and increase their self-perceived health, similarly to the benefits seen with physically going outdoors. In addition to the known risks to older adults and those with chronic conditions, we are already seeing evidence that people with lower socioeconomic status are disproportionally affected by this virus 4, 5 (higher burden of chronic medical conditions leading to higher risk of morbidity and mortality; less ability overall to socially distance leading to higher risk of infection; less financial cushioning leading to worse financial distress, etc).
    keywords: care; health; pandemic; patients
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        item: #6723 of 7819
          id: cord-342566-ym81lce9
      author: barasa, s.
       title: The major predictors of testing positive for COVID-19 among symptomatic hospitalized patients
        date: 2020-09-13
       words: 3221
      flesch: 46
     summary: Our study hypothesized that COVID-19 positive patients were more likely to have lymphopenia and or bilateral chest image abnormality in association with cough, fever, dyspnea or weakness compared to COVID-19 negative patients. The median age and the interquartile age range for COVID-19 positive and negative patients was not significantly different, although the age range of COVID-19 positive patients was 47 -85 years, while the age range of COVID-19 negative patients was 23 to 96 years.
    keywords: cough; covid-19; patients; prevalence; study
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        item: #6724 of 7819
          id: cord-342569-ja96xfns
      author: Azer, Samy A.
       title: COVID-19: Pathophysiology, diagnosis, complications and Investigational therapeutics
        date: 2020-08-05
       words: 2672
      flesch: 39
     summary: Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding A comparative study on the clinical features of COVID-19 pneumonia to other pneumonias Liver injury during highly pathogenic human coronavirus infections Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study COVID-19 and Liver Dysfunction: Current Insights and Emergent Therapeutic Strategies COVID-19-associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features Clinical characteristics of 3,062 COVID-19 patients: a metaanalysis Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Guidelines for Laboratory Diagnosis of Coronavirus Disease 2019 (COVID-19) in Korea Laboratory diagnosis of emerging human coronavirus infections -the state of the art Sensitive and specific monoclonal antibody-based capture enzyme immunoassay for detection of nucleocapsid antigen in sera from patients with severe acute respiratory syndrome Whole body point of care ultrasound for COVID-19: a multisystem approach to a multi-system disease A diagnostic model for coronavirus disease 2019 (COVID-19) based on radiological semantic and clinical features: a multi-center study Epidemiological and initial clinical characteristics of patients with family aggregation of COVID-19 The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients A geroscience perspective on COVID-19 mortality Panton-Valentine Leukocidin-Secreting Staphylococcus aureus Approximately 5% of COVID-19 patients require to be admitted to intensive care unit because they develop severe disease complicated with acute respiratory distress syndrome
    keywords: acute; coronavirus; cov-2; covid-19; disease; infection; patients; protein; sars
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        item: #6725 of 7819
          id: cord-342577-sxl4ac0s
      author: Li, Yuchen
       title: Public awareness, emotional reactions and human mobility in response to the COVID-19 outbreak in China – a population-based ecological study
        date: 2020-09-25
       words: 4349
      flesch: 40
     summary: In the current study, we aimed to describe dynamic changes in the public's emotional reactions and daily mobility patterns, especially self-limiting mobility patterns, in the Chinese population during the outbreak period of COVID-19 in China. We observed a change in daily mobility patterns during the outbreak period in Sichuan Province compared with the same period 1 year earlier (Fig. 2) .
    keywords: cases; comments; covid-19; data; mobility; outbreak; patterns; period; public; reactions
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        item: #6726 of 7819
          id: cord-342580-re7yqm1c
      author: Abdou, Hossam
       title: A Cautionary Tale of an Emergency Cerebrovascular Procedure in the COVID-19 Era
        date: 2020-09-02
       words: 1010
      flesch: 43
     summary: Hospitals all over the world have adopted intubation precautions 4 including minimizing staff in the room, donning appropriate personal protective equipment 5 (PPE) -typically powered air purifying respirators (PAPRs), using rapid sequence intubation 6 (RSI), and using video laryngoscopy [1] [2] [3] . Important equipment, including PAPRs and videolaryngoscopes, are at a premium 7 and are limited in availability.
    keywords: equipment; extubation; policies
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        item: #6727 of 7819
          id: cord-342589-n63yw2qy
      author: Guha, Santanu
       title: Managing ACS during COVID-19 infection: do not follow the traditional route
        date: 2020-04-15
       words: 1541
      flesch: 41
     summary: key: cord-342589-n63yw2qy authors: Guha, Santanu; Mukhopadhay, Somnath; Karak, Avik; Choudhury, Basabendra; Kapoor, Aditya; Yadav, Rakesh title: Managing ACS during COVID-19 infection: do not follow the traditional route date: 2020-04-15 journal: Indian Heart J DOI: 10.1016/j.ihj.2020.04.003 sha: doc_id: 342589 cord_uid: n63yw2qy COVID-19 pandemic is creating havoc in the world. Pre-existing cardiovascular disease (CVD) patients, having COVID-19 infection, are at higher risk of adverse outcomes and increased mortality.
    keywords: acs; covid-19; infection; patients; risk
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        item: #6728 of 7819
          id: cord-342599-558yn6pu
      author: Rinchai, Darawan
       title: A modular framework for the development of targeted Covid-19 blood transcript profiling panels
        date: 2020-05-22
       words: 5236
      flesch: 36
     summary: These data could, for instance, be used to refine the delineation of Covid-19 module sets. Immunological relevance: Lists of immunologically relevant genes were retrieved from Immport (44) , and were used along with membership to IPA pathways (Ingenuity Pathway Analysis, QIAGEN, Germantown MD) to annotate transcripts comprising Covid-19 module sets.
    keywords: abundance; blood; coronavirus; covid-19; data; immune; module; panel; patients; profiling; repertoire; sars; sets; transcripts
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        item: #6729 of 7819
          id: cord-342603-k0f33p3l
      author: Spyropoulos, Alex C.
       title: Scientific and Standardization Committee Communication: Clinical Guidance on the Diagnosis, Prevention and Treatment of Venous Thromboembolism in Hospitalized Patients with COVID‐19
        date: 2020-05-27
       words: 3805
      flesch: 22
     summary: Initial data support a high incidence of thromboembolic disease, and especially VTE, in hospitalized COVID-19 patients, as well as poorer outcomes for COVID-19 patients with pre-existing cardiovascular disease [3, 7] . Early reports suggest a high incidence of VTE in hospitalized COVID-19 patients, particularly those with severe illness, that is similar to the high VTE rates observed in patients with other viral pneumonias, including severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS-CoV)
    keywords: article; covid-19; lmwh; management; patients; risk; thromboprophylaxis; vte
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        item: #6730 of 7819
          id: cord-342616-k65501xp
      author: Feng, Zhichao
       title: The Use of Adjuvant Therapy in Preventing Progression to Severe Pneumonia in Patients with Coronavirus Disease 2019: A Multicenter Data Analysis
        date: 2020-04-10
       words: 4286
      flesch: 39
     summary: The clinical symptoms at illness onset also differed, with severe patients more likely to present with fever and shortness of breath. 18, 19 Therefore, the objective of this study was to investigate the role of several adjuvant treatments in preventing severe pneumonia in COVID-19 patients from seven cities in Hunan province, China.
    keywords: acei; arb; covid-19; license; medrxiv; patients; pneumonia; preprint; therapy
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        item: #6731 of 7819
          id: cord-342625-31fe1neb
      author: Baba, Hiroaki
       title: Prolonged presence of SARS-CoV-2 in a COVID-19 case with rheumatoid arthritis taking iguratimod treated with ciclesonide
        date: 2020-07-01
       words: 1457
      flesch: 41
     summary: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly across the world, yet investigations of in patients with rheumatologic disease taking disease-modifying antirheumatic drugs (DMARDs) with immunomodulatory or immunosuppressive effects remain scarce [1] . No increased risks of morbidity or severity have been reported to date for diseases related to COVID-19, including severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), in patients taking the immunomodulatory DMARDs such as hydroxychloroquine and sulfa, gold preparations, and immunosuppressive DMARDs such as methotrexate, cyclosporin and azathioprine [4] [5] [6] .
    keywords: covid-19; day; iguratimod; patient
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        item: #6732 of 7819
          id: cord-342631-ryibszjm
      author: Shoer, S.
       title: Who should we test for COVID-19?A triage model built from national symptom surveys
        date: 2020-05-21
       words: 4162
      flesch: 45
     summary: An ideal dataset for purposes of devising a classifier should include a large random sampling of the population, but such data coupled with symptom surveys is currently unavailable at large-scale. In addition, in order to capture nonlinear interactions and interactions amongst features, in both cases we also constructed models using a Gradient Boosting Decision Trees algorithm 9 .
    keywords: covid-19; license; medrxiv; model; preprint; survey; version
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        item: #6733 of 7819
          id: cord-342636-mmlnm3mz
      author: Situngkir, H.
       title: The Pandemics in Artificial Society: Agent-Based Model to Reflect Strategies on COVID-19
        date: 2020-07-29
       words: 3584
      flesch: 51
     summary: The conceptualizations of the neighborhood are other agents as perceived within radii '*!,-.&$+ , compared to her distance to others. Whenever the agent wants to leave her grid, she will be pushed back by the wall so that she can't interact with other agents in another grid.
    keywords: agent; aspects; countries; covid-19; intervention; model; people
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        item: #6734 of 7819
          id: cord-342703-vbq1o25l
      author: Huang, J.
       title: Comparing biomarkers for COVID-19 disease with commonly associated preexisting conditions and complications.
        date: 2020-10-05
       words: 4207
      flesch: 32
     summary: key: cord-342703-vbq1o25l authors: Huang, J. title: Comparing biomarkers for COVID-19 disease with commonly associated preexisting conditions and complications. To determine if specific biological processes overlap between COVID-19 disease and related comorbidities, modules of intercorrelated proteins were identified and used to cross-examine associations between disease characteristics, preexisting conditions, and relevant biomarkers established in previous studies.
    keywords: covid-19; disease; license; medrxiv; patients; preprint; protein; severity
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        item: #6735 of 7819
          id: cord-342708-yimysnvx
      author: Patel, Neeral R.
       title: Overall Impact of the COVID-19 Pandemic on Interventional Radiology Services: A Canadian Perspective
        date: 2020-08-30
       words: 3622
      flesch: 36
     summary: The COVID-19 pandemic has had a profound impact on IR services in Canada, particularly for elective cases. Guidelines should be followed to ensure patient and staff safety while resuming IR services.
    keywords: covid-19; pandemic; participants; procedures; radiology; respondents; services
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        item: #6736 of 7819
          id: cord-342716-h0d47023
      author: Park, Hojeong
       title: A Study on Herd Immunity of COVID-19 in South Korea: Using a Stochastic Economic-Epidemiological Model
        date: 2020-07-13
       words: 1864
      flesch: 58
     summary: The herd immunity calculated from economic-epidemiological model suggests that at least 62% of the susceptible population be vaccinated when COVID-19 vaccine becomes available. Two herd immunity concepts were compared to provide the optimal stockpile level of COVID-19 vaccine.
    keywords: covid-19; herd; immunity; model
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        item: #6737 of 7819
          id: cord-342734-37xduboo
      author: Thomé, Beatriz C.
       title: Ethical Considerations for Restrictive and Physical Distancing Measures in Brazil During COVID-19: Facilitators and Barriers
        date: 2020-11-09
       words: 2580
      flesch: 42
     summary: Adherence to restrictive and physical distancing measures depends on the general acceptance of public health measures as well as communities’ financial leverage. Adherence to public health measures largely relies on the public's trust in health systems.
    keywords: brazil; covid-19; distancing; health; measures; pandemic; public
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        item: #6738 of 7819
          id: cord-342746-2hbcbvt6
      author: Lane, J. C. E.
       title: Safety of hydroxychloroquine, alone and in combination with azithromycin, in light of rapid wide-spread use for COVID-19: a multinational, network cohort and self-controlled case series study
        date: 2020-04-10
       words: 6753
      flesch: 41
     summary: For the study of HCQ combined with AZM, follow up started when the second of the two co-administered treatments was initiated while still exposed to the first treatment (e.g. when AZM started during a period of HCQ use, or when HCQ started during a period of AZM use). HCQ use was assumed to be chronic in the management of RA, and AZM was assumed an acute prescription for infection treatment, and therefore inferred persistent exposure to AZM was assessed by allowing up to 30 days between dispensing or prescription records.
    keywords: author; copyright; covid-19; hcq; holder; hydroxychloroquine; license; medrxiv; medrxiv preprint; peer; perpetuity; preprint; study; treatment
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        item: #6739 of 7819
          id: cord-342756-rgm9ffpk
      author: Senger, Mario Roberto
       title: COVID-19: molecular targets, drug repurposing and new avenues for drug discovery
        date: 2020-10-02
       words: 16157
      flesch: 39
     summary: Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19 Virtual screening, ADME/T, and binding free energy analysis of anti-viral, anti-protease, and anti-infectious compounds against NSP10/ NSP16 methyltransferase and main protease of SARS CoV-2 Targeting SARS-COV-2 non-structural protein 16: a virtual drug repurposing study Ready, set, fuse! (148) Other targets -Apart from SARS-CoVs infection, some relevant molecular targets of other viral diseases and host metabolism have also been investigated in COVID-19 drug discovery, such as viral neuraminidases and the DPP4 cell receptor.
    keywords: ace2; activity; cells; coronavirus; cov-2; covid-19; disease; drug; fig; host; human; infection; inhibitors; lopinavir; mers; new; patent; patients; potential; protease; protein; remdesivir; replication; repurposing; ritonavir; rna; sars; structure; studies; syndrome; target; treatment; trials
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        item: #6740 of 7819
          id: cord-342767-n9ux7gqm
      author: Head, Michael G
       title: A real-time policy dashboard can aid global transparency in the response to coronavirus disease 2019
        date: 2020-07-10
       words: 1032
      flesch: 46
     summary: A ‘policy dashboard’ could act as a hub to show the localised reasoning behind COVID-19 policy decisions and allow the global health community to provide further support to governments and international stakeholders. Available from Retracted: Hydroxychloroquine or chloroquine with or without a macrolide for treatment of COVID-19: a multinational registry analysis Coalition letter regarding transparency and access in response to COVID-19 Evidence informing the UK's COVID-19 public health response must be transparent COVID-19): scientific evidence supporting the UK government response Oxford COVID-19 Evidence Service Monitoring investments in coronavirus research and development Funding:
    keywords: covid-19; evidence; time
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        item: #6741 of 7819
          id: cord-342771-0p5x5ihh
      author: Huang, Qianwen
       title: Targeting inflammation and cytokine storm in COVID-19
        date: 2020-06-27
       words: 2154
      flesch: 34
     summary: Corticosteroids, such as methylprednisolone and dexamethasone, were considered as one of the options for COVID-19 patients with cytokine storm [4] based on their inhibition on many inflammatory genes and previous clinical use in other viral diseases. Cytokine storm represents an exaggerated immune response characterized by overproduction of pro-inflammatory cytokines and chemokines such as IFN-γ, TNF-α, IL-6, IL-1β, IL-18, CXCL8 and CXCL10.
    keywords: covid-19; cytokine; il-6; inflammation; patients; storm
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        item: #6742 of 7819
          id: cord-342776-hkjhqgie
      author: Jewett, Anahid
       title: The Potential Effect of Novel Coronavirus SARS-CoV-2 on NK Cells; A Perspective on Potential Therapeutic Interventions
        date: 2020-07-10
       words: 3615
      flesch: 31
     summary: Similar to SARS-CoV-2 infection in patients, decreased NK cell function in the tumor microenvironment, and peripheral blood of cancer patients as well as down-modulation of CD16 receptors on the surface of NK cells have been reported previously (23, (35) (36) (37) (38) (39) (40) . This commentary outlines what is the reported literature thus far on the effect of virus on NK cells known to kill virally infected cells.
    keywords: cells; cov-2; covid-19; disease; infection; patients; sars
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        item: #6743 of 7819
          id: cord-342786-dl8vjwfn
      author: Sattar, Yasar
       title: COVID-19 Cardiovascular Epidemiology, Cellular Pathogenesis, Clinical Manifestations and Management
        date: 2020-07-14
       words: 5274
      flesch: 32
     summary: A study reports that heart failure is a common manifestation of COVID-19 patients, seen in 23% of affected patients [47] . Hypertension is frequently seen in COVID-19 patients however it is unclear whether it is a risk factor for acquiring COVID-19.
    keywords: angiotensin; cardiac; coronavirus; cov-2; covid-19; disease; dysfunction; infection; patients; receptor; risk; sars; syndrome
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        item: #6744 of 7819
          id: cord-342810-41dghl0c
      author: Nguyen, Thanh N.
       title: Subarachnoid hemorrhage guidance in the era of the COVID-19 pandemic -An opinion to mitigate exposure and conserve personal protective equipment
        date: 2020-06-05
       words: 3909
      flesch: 34
     summary: In patients in whom aneurysm securing is delayed for unavoidable reasons, empiric use of prothrombotic agents such as aminocaproic acid or tranexamic acid should be avoided due to the presumptive increased risk of disseminated intravascular coagulation or pro-thrombotic conditions in COVID-19 patients. Maintain euvolemia during the aneurysm procedure but take care to avoid hypervolemia / overresuscitation given the risk of pulmonary complications in COVID-19 patients may be worsened by excessive fluid intake.
    keywords: care; clinical; covid-19; hemorrhage; pandemic; patients; ppe; procedure; risk; room; sah
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        item: #6745 of 7819
          id: cord-342822-d7jx06mh
      author: Izadi, N.
       title: The epidemiologic parameters for COVID-19: A Systematic Review and Meta-Analysis
        date: 2020-05-06
       words: 3375
      flesch: 42
     summary: Estimation Using Japanese Passengers Data on Evacuation Flights Serial interval of novel coronavirus (COVID-19) infections Ascertainment rate of novel coronavirus disease (COVID-19) in Japan Reconciling early-outbreak estimates of the basic reproductive number and its uncertainty: framework and applications to the novel coronavirus (SARS-CoV-2) outbreak. medRxiv Estimating the daily trend in the size of the COVID-19 infected population in Wuhan Incubation Period and Other Epidemiological Characteristics of 2019 Novel Coronavirus Infections with Right Truncation: A Statistical Analysis of Publicly Available Case Data Time-varying transmission dynamics of Novel Coronavirus Pneumonia in China Early epidemiological assessment of the transmission potential and virulence of coronavirus disease 2019 (COVID-19) in Wuhan City: China Transmission potential of COVID-19 in Iran The Rate of Underascertainment of Novel Coronavirus (2019-nCoV) Infection:
    keywords: coronavirus; covid-19; license; medrxiv; novel; peer; preprint
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        item: #6746 of 7819
          id: cord-342841-b1rucgmg
      author: Di Carlo, Francesco
       title: Telepsychiatry and other cutting edge technologies in Covid‐19 pandemic: bridging the distance in mental health assistance
        date: 2020-09-18
       words: 5261
      flesch: 38
     summary: Considering the experiences from past serious virus pandemics, improvement of mental health care are needed [69] . Accepted Article Mental Health, Risk Factors, and Social Media Use During the COVID-19 Epidemic and Cordon Sanitaire Among the Community and Health Professionals in Wuhan, China: Cross-Sectional Survey Mental health consequences during the initial stage of the 2020 Coronavirus pandemic (COVID-19) in Spain Epidemic of COVID-19 in China and associated Psychological Problems Patients with mental health disorders in the COVID-19 epidemic Preventing problematic internet use during the COVID-19 pandemic: Consensus guidance Problematic Internet use (PIU), personality profiles and emotion dysregulation in a cohort of young adults: trajectories from risky behaviors to addiction Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2) Mental Health Response to the COVID-19 Outbreak in China Global mental health and COVID-19.
    keywords: article; care; copyright; covid-19; health; pandemic; patients; review; services; treatment; use
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        item: #6747 of 7819
          id: cord-342852-8wlqbwdi
      author: Chen, Jie
       title: Risk factors for depression and anxiety in healthcare workers deployed during the COVID-19 outbreak in China
        date: 2020-09-10
       words: 3995
      flesch: 49
     summary: A novel coronavirus outbreak of global health concern National Health Commission of the People's Republic of China (2020-03-04) Daily briefing on novel coronavirus cases in China Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19 Severe acute respiratory syndrome (SARS) in Hong Kong in 2003: stress and psychological impact among frontline healthcare workers The mental health of medical workers in Wuhan, China dealing with the 2019 novel coronavirus Dynamics of a stressful encounter: Cognitive appraisal, coping, and encounter outcomes The relationship between burnout, depression and anxiety: a systematic review and meta-analysis Prevalence of burnout, depression, anxiety and stress in Australian midwives: a cross-sectional survey Responding to the hidden pandemic for healthcare workers: stress 2020) Occurrence, prevention, and management of the psychological effects of emerging virus outbreaks on healthcare workers: rapid review and meta-analysis Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Relationship between anxiety and burnout among Chinese physicians: a moderated mediation model Work-family conflict and burnout among Chinese female nurses: the mediating effect of psychological capital The mediating role of coping style in the relationship between psychological capital and burnout among Chinese Nurses Nurse burnout and its association with occupational stress in a cross-sectional study in Shanghai Prevalence and factors associated with occupational burnout among HIV/AIDS healthcare workers in China: a cross-sectional study Associations between erectile dysfunction and psychological disorders (depression and anxiety): a crosssectional study in a Chinese population Reliability and validity of a generalized anxiety scale in general hospital outpatients Validation of the generalized anxiety disorder-7 (GAD-7) among Chinese people with epilepsy The patient health questionnaire somatic, anxiety, and depressive symptom scales: a systematic review Reliability and validity of the Chinese version of the patient health questionnaire (PHQ-9) in the general population Validity study of Patient Health Questionnaire-9 items for Internet screening in depression among Chinese university students Logistic regression diagnostics: understanding how well a model predicts outcomes Managing workplace stress in outpatient nursing Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission Genomic characterisation and epidemiology of 2019 novel. We conducted a cross-sectional survey of psychological state on Chinese healthcare workers by delivering online questionnaires through WeChat platform (https ://www.
    keywords: anxiety; burnout; covid-19; depression; healthcare; study; symptoms; workers
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        item: #6748 of 7819
          id: cord-342857-vj6sw2ne
      author: McCullough, Peter A.
       title: Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection
        date: 2020-08-07
       words: 2216
      flesch: 24
     summary: As with azithromycin, doxycycline has the Because ambulatory centers and clinics have been reticent to have face-to-face visits for COVID-19 patients, telemedicine is a reasonable platform for monitoring. A randomized, double-blind, placebo-controlled trial Can Zn Be a Critical Element in COVID-19 Treatment? Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro and zinc ionophores block the replication of these viruses in cell culture Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State Treatment with Hydroxychloroquine, Azithromycin, and Combination in Patients Hospitalized with COVID-19 Risk Factors for Mortality in Patients with COVID-19 in Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology Macrolides and viral infections: focus on azithromycin in COVID-19 pathology Outcomes of 3,737 COVID-19 patients treated with hydroxychloroquine/azithromycin and other regimens in Marseille, France: A retrospective analysis Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France Early Outpatient Treatment of Symptomatic Patients that Should be Ramped-Up Immediately as Key to the Pandemic Crisis Clinical failure with and without empiric atypical bacteria coverage in hospitalized adults with community-acquired pneumonia: a systematic review and meta-analysis Doxycycline as a potential partner of COVID-19 therapies Therapeutic Potential for Tetracyclines in the Treatment of COVID-19Pharmacotherapy 2020 Doxycycline Is a Costeffective Therapy for Hospitalized Patients With Community-Acquired Pneumonia an antiviral for COVID-19 A review of the safety of favipiravir -a
    keywords: coronavirus; covid-19; disease; patients; sars; therapy; treatment
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        item: #6749 of 7819
          id: cord-342873-eu7f0zjm
      author: Yeleswaram, Swamy
       title: Inhibition of cytokine signaling by ruxolitinib and implications for COVID-19 treatment
        date: 2020-06-23
       words: 2894
      flesch: 38
     summary: Patients with severe COVID-19 experience elevated plasma levels of pro-inflammatory cytokines, which can result in cytokine storm, followed by massive immune cell infiltration into the lungs leading to alveolar damage, decreased lung function, and rapid progression to death. Furthermore, hematologic parameters including platelet, red blood cell, and neutrophil counts improved within the first week of ruxolitinib treatment.
    keywords: covid-19; cytokine; disease; jak2; patients; ruxolitinib; storm; treatment
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        item: #6750 of 7819
          id: cord-342888-o7ezn9dd
      author: Wang, Lei-Yun
       title: Remdesivir and COVID-19
        date: 2020-10-01
       words: 1227
      flesch: 47
     summary: The suggestion made by Jessie K Edwards and colleagues to report the effect of remdesivir stratified by lopinavir-ritonavir is important, although the potential effect of lopinavir-ritonavir was not confirmed in COVID-19 patients. Although the number of confirmed COVID-19 patients at the time was still large in Wuhan, China, there were Samira Asma and colleagues 1 show the complexity of the global monitoring of health-related Sustainable Develop ment Goals (SDGs) and argue for convergence, harmonisation, and strong data science.
    keywords: colleagues; covid-19; patients; remdesivir
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        item: #6751 of 7819
          id: cord-342902-y1v8wzxq
      author: Yuan, Shuofeng
       title: Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters
        date: 2020-10-07
       words: 5699
      flesch: 35
     summary: The effective concentration of clofazimine against SARS-CoV-2 (half maximal effective concentration 310 nM) is clinically achievable with standard dosage in patients (peak serum concentration 861 nM) 13 . Clofazimine has a relatively long duration of action with the mean elimination half-life approximately 25 days, thus we performed prophylactic treatment of hamsters with clofazimine before intranasally challenged with 10 5 PFU of SARS-CoV-2 ( Figure 4a ).
    keywords: antiviral; cells; clofazimine; cov-2; covid-19; drug; figure; human; infection; lung; patients; remdesivir; replication; rna; sars; treatment
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        item: #6752 of 7819
          id: cord-342919-ls2q1g0v
      author: Balsamo, Michela
       title: Italians on the Age of COVID-19: The Self-Reported Depressive Symptoms Through Web-Based Survey
        date: 2020-10-16
       words: 6939
      flesch: 37
     summary: The purpose of this study was to assess the prevalence of depressive symptoms in specific sociodemographic categories during the COVID-19 quarantine lockdown and the potential factors that contribute to, or mitigate, these effects. In the very early stage of the nationwide lockdown, 3,672 quarantined Italian adult residents (65% females, ranging from 18 to 85 years) participated in a web-based cross-sectional survey, including measures of depressive symptoms, which were measured by the Teate depression inventory, and state anxiety levels.
    keywords: anxiety; covid-19; depressive; et al; health; model; participants; people; quarantine; risk; symptoms
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        item: #6753 of 7819
          id: cord-342929-y8857da3
      author: Desai, Urvi
       title: Guidance for Resumption of Routine Electrodiagnostic Testing during the COVID‐19 Pandemic
        date: 2020-05-28
       words: 1369
      flesch: 52
     summary: We provide consensus guidance for resumption of EDX testing, addressing scheduling, patient arrival and registration, use of personal protective equipment, COVID‐19 screening and testing, the performance of EDX in outpatient and inpatient settings, cleaning and maintenance of the EDX equipment and laboratory, balancing trainee safety and training requirements, and patient care issues. Accompanying persons should be asked to wait outside the institution unless their presence is necessary to perform EDX testing (e.g., in young children, patients with cognitive impairment).
    keywords: covid-19; edx; patients; testing; use
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        item: #6754 of 7819
          id: cord-342930-f7cw2ca6
      author: Portincasa, Piero
       title: Hepatic consequences of COVID-19 infection. Lapping or biting?
        date: 2020-06-01
       words: 3018
      flesch: 39
     summary: This is particularly true if patients are older or have a pre-existing history of liver diseases. The mechanisms and strategies to protect from hepatic ischemia-32 reperfusion injury Liver -guardian, modifier and target of sepsis Specific ACE2 expression in cholangiocytes may 39 cause liver damage after 2019-nCoV infection Ischaemia reperfusion injury in liver 41 transplantation: Cellular and molecular mechanisms Immune responses in COVID-19 and potential vaccines: 1 Lessons learned from SARS and MERS epidemic Pathogen recognition and Toll-like receptor targeted therapeutics in innate 3 immune cells Infection of neonatal 5 mice with sindbis virus results in a systemic inflammatory response syndrome Systemic viral infections and collateral damage in the liver Evolution of the immune system in humans from infancy 10 to old age MCP-1 Expression in an Autocrine Manner in Hepatocytes during Acute Mouse Liver Injury signaling axis is a key mediator of hepatic ischemia-reperfusion injury Mitochondrial 17 oxidative injury in rat fatty livers exposed to warm ischemia-reperfusion The reduced 20 tolerance of rat fatty liver to ischemia reperfusion is associated with mitochondrial oxidative injury People who are at higher risk for severe illness Study of the relationship SARS and hepatitis virus B Care of patients 26 with liver disease during the COVID-19 pandemic: EASL-ESCMID position paper The global burden of liver disease: the major 29 impact of China Prevention of SARS-CoV-2 infection in patients with 31 decompensated cirrhosis Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population 34 Utilizing Ultrasound and Liver Biopsy: A Prospective Study Systematic review: the epidemiology and natural history of 36 non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults Prevalence of 39 nonalcoholic fatty liver disease in the United States: the Third National Health and Nutrition 40 Examination Survey Changes in the prevalence 1 of the most common causes of chronic liver diseases in the United States from Exercising the hepatobiliary-gut axis.
    keywords: coronavirus; covid-19; damage; disease; infection; injury; liver; patients; study
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        item: #6755 of 7819
          id: cord-342972-bjv8biop
      author: Smith, Michael D
       title: COVID-19, Food Insecurity, and Migration
        date: 2020-08-25
       words: 3369
      flesch: 42
     summary: Strengthening the Enabling Environment for Food Security and Nutrition Food insecurity is associated with subjective well-being among individuals from 138 countries in the 2014 Gallup world poll Food insecurity was more strongly associated with poor subjective well-being in more-developed countries than in less-developed countries International migration desires related to subjective well-being Remittances, household expenditure and investment in Guatemala Domestic and international migration from rural Mexico: disaggregating the effects of network structure and composition Linkages between Migration, Agriculture, Food Security and Rural Development Where the rain falls: evidence from 8 countries on how vulnerable households use migration to manage the risk of rainfall variability and food insecurity Rainfall variability, food insecurity and migration in Cabrican Climate, migration, and the local food security context: introducing Terra Populus Linking food security, migration and development Assessing the Effects of Food Insecurity on International Migration. The interaction between COVID-19 and the drop in economic activity will lead to increased food insecurity within and across countries.
    keywords: countries; covid-19; effects; food; insecurity; migration; policy; world
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        item: #6756 of 7819
          id: cord-342974-g6ltr6am
      author: Hull, S. A.
       title: Suspected COVID-19 in primary care: how GP records contribute to understanding differences in prevalence by ethnicity.
        date: 2020-05-26
       words: 3096
      flesch: 51
     summary: (11, 12) Practices worked collectively to provide separate locations for the necessary physical examinations of people with suspected COVID-19 cases and for those with other medical problems. https://doi.org/10.1101/2020.05.23.20101741 doi: medRxiv preprint Using patient level data from the GP record this study documents the numbers of suspected COVID-19 cases presenting to practices through the peak of the London epidemic ( Figure 2 ).
    keywords: cases; covid-19; data; license; medrxiv; practices; preprint
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        item: #6757 of 7819
          id: cord-342984-3qbvlbwo
      author: Allington, Daniel
       title: Health-protective behaviour, social media usage and conspiracy belief during the COVID-19 public health emergency
        date: 2020-06-09
       words: 3858
      flesch: 39
     summary: All three studies found a negative relationship between COVID-19 conspiracy beliefs and COVID-19 health-protective behaviours, and a positive relationship between COVID-19 conspiracy beliefs and use of social media as a source of information about COVID-19. This raises the possibility that the circulation of COVID-19 conspiracy beliefs might be associated with similar risks.
    keywords: behaviours; beliefs; conspiracy; covid-19; health; media; relationship
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        item: #6758 of 7819
          id: cord-342989-9ie8mx4l
      author: Lam, Simon Ching
       title: Perceived Risk and Protection From Infection and Depressive Symptoms Among Healthcare Workers in Mainland China and Hong Kong During COVID-19
        date: 2020-07-15
       words: 4023
      flesch: 40
     summary: On average, Hong Kong HCWs had a higher PHQ-9 score (mean [SD]: 10.5 Perhaps of greater concern is the higher levels of concern expressed by Hong Kong HCWs expressing in relation to the inadequate provision of PPE (77.5% in Hong Kong versus 24.0% in Hubei and 32.9% in Guangdong), which we will now discuss.
    keywords: covid-19; depression; face; hcws; health; hong; kong; risk
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        item: #6759 of 7819
          id: cord-343008-y2pt43am
      author: Tee, Cherica A
       title: Psychological State and Associated Factors During the 2019 Coronavirus Disease (COVID-19) Pandemic Among Filipinos with Rheumatoid Arthritis or Systemic Lupus Erythematosus
        date: 2020-09-22
       words: 3907
      flesch: 43
     summary: However, the needed shift in focus of health care resources for COVID-19 patients and the implementation of community quarantine have significantly limited the access of persons with chronic diseases to medical care and medicines. One other factor that may have contributed to the patients' anxieties was the conflicting reports on the effects (beneficial to harmful) of hydroxychloroquine in COVID-19 patients.
    keywords: anxiety; covid-19; depression; health; impact; lupus; pandemic; patients; stress
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        item: #6760 of 7819
          id: cord-343018-8ghon5nb
      author: Rajabally, Yusuf A.
       title: Management challenges for chronic dysimmune neuropathies during the COVID‐19 pandemic
        date: 2020-04-24
       words: 1849
      flesch: 21
     summary: Immunomodulatory and particularly immunosuppressive therapies may compromise the immune system's ability to effectively fight off infection with COVID-19, and this concern will persist for an indeterminate time and impact upon patient management. In such patients, the urgency of diagnosis should be balanced against the risks of hospital/medical facility attendance for clinical evaluation and diagnostic tests.
    keywords: chronic; cidp; covid-19; inflammatory; patients; treatment
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        item: #6761 of 7819
          id: cord-343021-gqem6bxj
      author: Allam, Zaheer
       title: Oil, Health Equipment, and Trade: Revisiting Political Economy and International Relations During the COVID-19 Pandemic
        date: 2020-07-24
       words: 6026
      flesch: 42
     summary: Similar measures have been advanced in different other countries, which adds to the protectionism shown through border restrictions and banning of flights and exportation of medical supplies. Other countries imposed nationwide lockdowns and curfews, only exempting essential service providers.
    keywords: china; coronavirus; countries; covid-19; demand; oil; pandemic; production; states; supplies; united; world
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        item: #6762 of 7819
          id: cord-343027-ks3fn9pq
      author: Fraser, Nicholas
       title: Preprinting the COVID-19 pandemic
        date: 2020-09-18
       words: 5713
      flesch: 48
     summary: Only marginally 135 faster screening was detected for COVID-19 preprints than for non-COVID-19 preprints (Fig. 2B) when 136 adjusting for differences between servers (two-way ANOVA, interaction term; F1,14808 = 69.13, p < 137 0.001). COVID-19 preprints 185 did not discernibly differ in number of versions compared with non-COVID-19 preprints ( Mann-Whitney, p < 0.001)
    keywords: biorxiv; covid-19; data; fig; medrxiv; non; pandemic; preprints; research; time
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        item: #6763 of 7819
          id: cord-343038-j58f1lwa
      author: Henry, Brandon Michael
       title: Preliminary epidemiological analysis on children and adolescents with novel coronavirus disease 2019 outside Hubei Province, China: an observational study utilizing crowdsourced data
        date: 2020-03-06
       words: 5183
      flesch: 54
     summary: The number of reported COVID-19 cases in pediatric patients is rapidly increasing around the world. However, the number of reported pediatric cases, at least in the early stages of this outbreak, is limited.
    keywords: cases; children; covid-19; data; license; medrxiv; patients; preprint
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        item: #6764 of 7819
          id: cord-343052-dc9s2rau
      author: Murgo, Salvatore
       title: Haemoptysis treated by bronchial artery embolisation in severe acute respiratory syndrome coronavirus 2: case report
        date: 2020-09-05
       words: 1876
      flesch: 41
     summary: Baseline laboratory values showed a slightly prolonged activated partial thromboplastin time (APTT) and increased D-dimer level which have both been reported in COVID-19 patients and associated with poor prognosis (Tang et al. 2020) . The lungs are the target organ for SARS-CoV-2, and progressive respiratory failure is the primary cause of death in COVID-19 patients.
    keywords: covid-19; embolisation; haemoptysis; patient
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        item: #6765 of 7819
          id: cord-343061-4ab7ycwp
      author: Lakhani, Ali
       title: Introducing the Percent, Number, Availability, and Capacity [PNAC] Spatial Approach to Identify Priority Rural Areas Requiring Targeted Health Support in Light of COVID‐19: A Commentary and Application
        date: 2020-04-11
       words: 672
      flesch: 46
     summary: It is expected that future applications of the PNAC method could be of particular benefit to rural service planning in light of COVID-19, as the approach considers both the demographic distribution (for example age) and service capacity issues unique to rural areas. 3 Aging populations in rural and remote communities may be especially vulnerable to the COVID-19 pandemic, and in part, this is due to the availability and capacity of rural health services.
    keywords: covid-19; health; rural
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        item: #6766 of 7819
          id: cord-343072-3wuh6k6g
      author: Dong, Mengying
       title: Understand Research Hotspots Surrounding COVID-19 and Other Coronavirus Infections Using Topic Modeling
        date: 2020-03-30
       words: 3325
      flesch: 45
     summary: Our findings can potentially aid governments and the research community in understanding recent development of the research field, optimizing research topic decision, and monitoring new scientific or technological activities. . The purpose of this work was to conduct LDA modeling for semantic and quantitative evaluations of the current status of literature on CoV infections as well as COVID-19, identify broad research topics and how these topics interact with one another.
    keywords: author; covid-19; license; medrxiv; preprint; research; topics
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        item: #6767 of 7819
          id: cord-343073-lwbddab2
      author: Antiporta, D. A.
       title: Emerging Mental Health Challenges, Strategies and Opportunities in the context of the COVID-19 Pandemic: Perspectives from South American Decision-makers.
        date: 2020-07-18
       words: 4994
      flesch: 41
     summary: The creation and inclusion of commissions for mental health within technical working groups will allow mental health services to be prioritized not only in the current response but also in the post-pandemic scenario. The semi-structured questionnaire had 12 questions clustered into 3 main sections: emerging challenges in mental health, current and potential strategies to face the pandemic, and, key elements for mental health reform.
    keywords: care; covid-19; health; license; pandemic; preprint; services; strategies
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        item: #6768 of 7819
          id: cord-343082-46lo7xtx
      author: Awasthi, Ankit
       title: OUTBREAK of novel corona virus disease (COVID-19): Antecedence and aftermath
        date: 2020-07-25
       words: 3954
      flesch: 41
     summary: Later, it was reported to be effective in the treatment of COVID-19 patients also (Holshue et al., 2020) . Currently, vitamin C infusion is under clinical trial for the treatment of severe COVID-19 virus infected pneumonia as it plays important role in reducing inflammatory response and has antioxidant property.
    keywords: cells; combination; covid-19; kumar; patients; protein; sars; studies; treatment; vaccine; virus
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        item: #6769 of 7819
          id: cord-343087-vnvlnxnq
      author: Vacanti, Gaetano
       title: Reduced rate of admissions for acute coronary syndromes during the COVID-19 pandemic: an observational analysis from a tertiary hospital in Germany
        date: 2020-10-07
       words: 2875
      flesch: 37
     summary: Losing sight of the forest for the trees COVID-19 and disruptive modifications to cardiac critical care delivery: JACC review topic of the week Psychological stress, inflammation, and coronary heart disease Is quarantine related to immediate negative psychological consequences during the 2009 H1N1 epidemic? Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Endothelial cell infection and endotheliitis in COVID-19 This trend continued and even intensified after a fall in COVID-19 cases in the area; the number of ACS patients in April 2020 was 25% and in June 29% lower than in January 2020 (p-value for linear trend <0.001).
    keywords: acs; admissions; covid-19; department; outbreak; reduction
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        item: #6770 of 7819
          id: cord-343090-dsjq98ks
      author: Fragkou, Paraskevi C.
       title: Review of trials currently testing treatment and prevention of COVID-19
        date: 2020-05-23
       words: 2032
      flesch: 36
     summary: As with treatment trials, many prevention trials do not 327 report the study phase (n=4, 25%). Most studies were randomised (n=10, 63%) with a parallel Figure 5 shows 341 the total number of planned inclusions and the number of clinical trials for the ten most 342 frequently studied treatments, with hydroxychloroquine being the treatment associated with A clinical primary outcome was defined in 128 out of 198 therapeutic trials (65% ; Table 3) .
    keywords: covid-19; prevention; studies; table; treatment; trials
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        item: #6771 of 7819
          id: cord-343093-qjg5az3d
      author: Irie, Kei
       title: Pharmacokinetics of Favipiravir in Critically Ill Patients with COVID‐19
        date: 2020-05-31
       words: 2354
      flesch: 51
     summary: blood samples were obtained from the eligible patients to evaluate FPV concentration. Forty-nine samples were obtained from eligible patients to evaluate FPV concentrations.
    keywords: article; copyright; covid-19; fpv; patients
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        item: #6772 of 7819
          id: cord-343100-cljfh8es
      author: Chakraborty, Parthasarathi
       title: Exposure to Nitrogen Dioxide (NO(2)) from Vehicular Emission Could Increase the COVID-19 Pandemic Fatality in India: A Perspective
        date: 2020-07-15
       words: 3484
      flesch: 46
     summary: Although it is difficult to pinpoint the origin of atmospheric pollutants in the Indian cities, however, a rational analysis of concentrations of different atmospheric pollutants was carried out to identify the sources of atmospheric NO 2 in the different states of India. Therefore, regular exposure to different atmospheric pollutants could put a part of the Indian population under severe threat during the COVID-19 pandemic.
    keywords: atmospheric; concentration; covid-19; india; pandemic; pollutants
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        item: #6773 of 7819
          id: cord-343122-lppdauei
      author: Ribeiro, Helena
       title: Does Vitamin D play a role in the management of Covid-19 in Brazil?
        date: 2020-05-22
       words: 2487
      flesch: 31
     summary: The vitamin D deficiency pandemic: approaches for diagnosis, treatment and prevention The risks and benefits of sun exposure The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know Vitamin D supplementation and musculoskeletal health Pulmonary activation of vitamin D3 and preventive effect against interstitial pneumonia Vitamin D alleviates lipopolysaccharideinduced acute lung injury via regulation of the renin-angiotensin system Serum 25-hydroxyvitamin D and the incidence of acute viral respiratory tract infections in healthy adults Prevalence of hypovitaminosis D in elderly women in Italy: clinical consequences and risk factors The importance of vitamin D levels in autoimmune diseases Committee to Review Dietary Reference Intakes for Vitamin D and Calcium Vitamin D in the management of Covid-19 in Brazil Ribeiro H Epidemic influenza and vitamin D Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS) Influence of season and latitude on the cutaneous synthesis of vitamin D3: exposure to winter sunlight in Boston and Edmonton will not promote vitamin D3 synthesis in human skin Laboratory confirmation of the effect of occupational sun exposure on serum 25-hydroxyvitamin D concentration Air pollution, environmental chemicals, and smoking may trigger vitamin D deficiency: evidence and potential mechanisms Vitamin D effective ultraviolet wavelengths due to scattering in shade Environmental determinants of previtamin D synthesis in the United Arab Emirates Impact of high latitude, urban living and ethnicity on 25-hydroxyvitamin D status: a need for multidisciplinary action? Decreased bioavailability of vitamin D in obesity Evidence that vitamin d supplementation could reduce risk of influenza and COVID-19 infections and deaths Award received in 2018. Foods such as salmon and other oily fish, cod liver oil, egg yolk, milk and sun-dried mushrooms are natural sources of vitamin D. Vitamin D supplementation and fortified foods such as butter and milk are widely used in countries at high latitude with long winters such as the USA.
    keywords: covid-19; deficiency; diseases; exposure; levels; status; vitamin
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        item: #6774 of 7819
          id: cord-343127-n3fs8ph8
      author: Pousa, Pedro A.
       title: Extrapulmonary manifestations of COVID-19 in children: a comprehensive review and pathophysiological considerations
        date: 2020-09-22
       words: 5517
      flesch: 37
     summary: The emerging impasse of angiotensin blockade Renin-angiotensin-aldosterone (RAAS): the ubiquitous system for homeostasis and pathologies Covid-19: the renin-angiotensin system imbalance hypothesis Organ-specific distribution of ACE2 mRNA and correlating peptidase activity in rodents High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection Is the kidney a target of SARS The immune system of children: the key to understanding SARS-CoV-2 susceptibility? Kawasaki-like multisystem inflammatory syndrome in children during the COVID-19 prospective observational study Fatal outcome of COVID-19 disease in a 5-month infant with comorbidities Hyperinflammatory shock in children during COVID-19 pandemic Characteristics, cardiac involvement, and outcomes of multisystem inflammatory disease of childhood (MIS-C) associated with SARS-CoV-2 infection Anal swab findings in an infant with COVID-19 Special issues for coronavirus disease 2019 in children and adolescents SARS-CoV-2 infection in children in Parma Renal dysfunction in hospitalised children with COVID-19 Managing COVID-19-positive maternal-infant dyads: an Italian experience Atypical presentation of COVID-19 in young 24 Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study Gastrointestinal features in children with COVID-19: an observation of varied presentation in eight children Septic shock presentation in adolescents with COVID-19 Toxic shock-like syndrome and COVID-19: a case report of multisystem inflammatory syndrome in children Novel coronavirus infection in newborn babies aged < 28 days in China Febrile infant Acute myocardial injury: a novel clinical pattern in children with COVID-19 Cutaneous manifestations in COVID-19: a skin rash in a child Horizontal transmission of severe acute respiratory syndrome coronavirus 2 to a premature infant: multiple organ injury and association with markers of inflammation Tetralogy of Fallot palliation in a COVID-19 positive neonate A 55-day-old female infant infected with 2019 novel coronavirus disease: presenting with pneumonia, liver injury, and heart damage Hematuria associated with SARS-CoV-2 infection in a child Late-onset neonatal sepsis in a patient with COVID-19 COVID-19) infection: a case report and review of literature Novel coronavirus in a 15-day-old neonate with clinical signs of sepsis, a case report Thalassemic child presenting with anosmia due to COVID-19 infection in a paucisymptomatic infant: raising the index of suspicion in epidemic settings The cytokine storm and COVID-19 Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. However, this hypothesis remains speculative, as one study found that SARS-CoV-2 was not always detected in stool samples of COVID-19 patients with GI manifestations.
    keywords: ace2; children; cov-2; covid-19; disease; infection; manifestations; patients; sars; symptoms
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        item: #6775 of 7819
          id: cord-343168-gphud9yx
      author: Alyami, H. S.
       title: Depression and anxiety during 2019 coronavirus disease pandemic in Saudi Arabia: a cross-sectional study
        date: 2020-05-15
       words: 3862
      flesch: 49
     summary: Non-Saudi resident, females, elderly individuals aged 50 years and above and young individuals aged below 29 years, divorced and single, individuals with low education level, university students, and individuals with low income (2000 SR and below) tend to have higher depression median scores compared to others. Non-Saudi residents, females, and individuals with low education levels tend to have higher anxiety median scores compared to others.
    keywords: anxiety; covid-19; depression; participants; preprint; saudi; study
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        item: #6776 of 7819
          id: cord-343183-5jlnw6e0
      author: Sato, Ana Paula Sayuri
       title: Pandemic and vaccine coverage: challenges of returning to schools
        date: 2020-11-05
       words: 2647
      flesch: 34
     summary: Child vaccination coverage has declined sharply during the pandemic in several regions of the world 26, 28 . Here we go again: the reemergence of anti-vaccine activism on the Internet Routine childhood immunisation during the COVID-19 pandemic in Africa: a benefit-risk analysis of health benefits versus excess risk of SARS-CoV-2 infection Decline in child vaccination coverage during the COVID-19 Pandemic -Michigan Care Improvement Registry Impact of the COVID-19 pandemic on Emergency Department visits -United States Early impact of the coronavirus disease (COVID-19) pandemic and physical distancing measures on routine childhood vaccinations in England Effects of the COVID-19 pandemic on routine eediatric vaccine ordering and administration -United States Routine vaccination during covid-19 pandemic response The potential impact of COVID-19 pandemic on the immunization performance in Indonesia
    keywords: coverage; covid-19; health; immunization; pandemic; vaccination; vaccine
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        item: #6777 of 7819
          id: cord-343186-gsojxjp9
      author: Tang, Jieying
       title: Challenges in the management of critical ill COVID‐19 patients with pressure ulcer
        date: 2020-05-07
       words: 470
      flesch: 44
     summary: For patients with stage II or above pressure ulcers, the costs of medical resource increases significantly in our hospital. Therefore, how we can primarily prevent and appropriately manage the COVID-19 patients in ICU with pressure ulcer is an important issue.
    keywords: patients; pressure
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        item: #6778 of 7819
          id: cord-343201-98scxky8
      author: Thibault, Ronan
       title: How the Covid-19 epidemic is challenging our practice in clinical nutrition—feedback from the field
        date: 2020-09-16
       words: 5825
      flesch: 36
     summary: In an analysis of data from the Hong Kong cohort of patients and a meta-analysis, authors found that 17.6% of Covid-19 patients had GI symptoms and virus RNA fragments were detected in stool samples from 48.1% patient, even in stools collected after respiratory samples became negative [15] . Challenge 8-clinical situations and organizational constraints that may make EN unfeasible need to be known There are obvious clinical situations and organizational constraints increasing the risk of EN complications and the constraints related to NGT and EN are probably higher in Covid-19 patients than in standard medical patients: Issue 1-despite the absence of data in Covid-19 patients, the risk of EN complications may be higher in patients requiring high outflow oxygen Many patients are still receiving high flow nasal cannula therapy or noninvasive ventilation in many centers
    keywords: care; clinical; covid-19; epidemic; hospital; malnutrition; ngt; nutrition; patients; risk; support
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        item: #6779 of 7819
          id: cord-343205-zjw4fbfd
      author: Bhaskar, Sonu
       title: Telemedicine as the New Outpatient Clinic Gone Digital: Position Paper From the Pandemic Health System REsilience PROGRAM (REPROGRAM) International Consortium (Part 2)
        date: 2020-09-07
       words: 9177
      flesch: 25
     summary: A randomized controlled trial using high-fidelity simulation Self-management maintenance inhalation therapy with eHealth (SELFIE): observational study on the use of an electronic monitoring device in respiratory patient care and research Telemedicine in primary care for patients with chronic conditions: the ValCrònic Quasi-Experimental study Impact of telemonitoring home care patients with heart failure or chronic lung disease from primary care on healthcare resource use (the TELBIL study randomised controlled trial) Home-based telemonitoring of simple vital signs to reduce hospitalization in heart failure patients: real-world data from a community-based hospital Home telemonitoring of non-invasive ventilation decreases healthcare utilisation in a prospective controlled trial of patients with amyotrophic lateral sclerosis Adjusted cost analysis of video televisits for the care of people with amyotrophic lateral sclerosis Telehealth exercise-based cardiac rehabilitation: a systematic review and meta-analysis Feasibility and acceptability of inpatient palliative care E-family meetings during COVID-19 pandemic Telemedically augmented palliative care: Such patients are also at high risk of infection and poor outcomes, including mortality, among COVID-19-positive patients (3) .
    keywords: access; care; covid-19; disease; health; healthcare; heart; issues; management; monitoring; pandemic; patients; physician; rehabilitation; review; risk; stroke; systems; technologies; telehealth; telemedicine; use
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        item: #6780 of 7819
          id: cord-343219-0dwyv1vk
      author: Gellin, Bruce
       title: Why vaccine rumours stick—and getting them unstuck
        date: 2020-07-30
       words: 1938
      flesch: 50
     summary: That will certainly be the case when COVID-19 vaccines arrive, especially given the many new vaccine technologies that are being tested and the speed at which they are being developed. Thus, it is little surprise that the race to develop COVID-19 vaccines is running at full steam.
    keywords: covid-19; global; health; larson; vaccination; vaccine
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        item: #6781 of 7819
          id: cord-343249-npk92gra
      author: Hastie, C. E.
       title: Short Communication: Vitamin D and COVID-19 infection and mortality in UK Biobank
        date: 2020-06-28
       words: 999
      flesch: 43
     summary: Again, vitamin D concentration and vitamin D deficiency were associated with COVID-19 infection univariably but not multivariably (Table) . Conclusions Our findings do not support a potential link between vitamin D concentrations and risk of severe COVID-19 infection and mortality.
    keywords: covid-19; infection; vitamin
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        item: #6782 of 7819
          id: cord-343252-mtcqawxc
      author: Ruggieri, P.
       title: COVID-19 strategy in organizing and planning orthopedic surgery in a major orthopedic referral center in an area of Italy severely affected by the pandemic: experience of the Department of Orthopedics, University of Padova
        date: 2020-07-23
       words: 2893
      flesch: 44
     summary: Changes were done in our hospital by medical direction to reallocate resources to COVID-19 patients. Changes were done in the Orthopedic Department as well as in other departments of the university hospital by medical direction (D.D., one of our co-authors, our Medical Director) in order to minimize resources reallocating anesthesiologists, nurses, and medical assistants to dedicate to COVID-19 patients in new ICUs, semiintensive units, and recovery units.
    keywords: covid-19; hospital; italy; patients; swab
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        item: #6783 of 7819
          id: cord-343295-c3y6rtb7
      author: Chiara, Berardi
       title: The COVID-19 pandemic in Italy: policy and technology impact on health and non-health outcomes
        date: 2020-09-03
       words: 5896
      flesch: 44
     summary: Since 1993, health policies and constitutional reform have driven a decentralisation of the SSN (12) . The central government is responsible for public health interventions; however, the decentralisation of the Italian healthcare system hindered the implementation of a homogeneous strategy.
    keywords: appendix; covid-19; data; figure; government; health; healthcare; interventions; italy; measures; policy; rate; regions; system
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        item: #6784 of 7819
          id: cord-343322-vx3lub3s
      author: LUBANSU, Alphonse
       title: Reply to the Letter to the Editor Regarding " COVID-19 impact on neurosurgical practice: lockdown attitude and experience of a European academic center ".
        date: 2020-11-02
       words: 285
      flesch: 37
     summary: They anticipate any potential health care congestion according to the national and institutional forecasts by suspending non-urgent elective surgeries and outpatient activities and re-deployed wards, resources, and teams. Regarding COVID-19 impact on neurosurgical practice: lockdown attitude and experience of a European academic center .
    keywords: covid-19
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        item: #6785 of 7819
          id: cord-343325-cbrly7f5
      author: Denault, André Y.
       title: A proposed lung ultrasound and phenotypic algorithm for the care of COVID-19 patients with acute respiratory failure
        date: 2020-05-21
       words: 4029
      flesch: 35
     summary: medRxiv preprint Acute pulmonary embolism in COVID-19 patients on CT angiography and relationship to D-dimer levels Incidence of thrombotic complications in critically ill ICU patients with COVID-19 COVID-19 complicated by acute pulmonary embolism and right-sided heart failure Thrombotic events in SARS-CoV-2 patients: an urgent call for ultrasound screening Lung ultrasound for daily monitoring of ARDS patients on extracorporeal membrane oxygenation: preliminary experience Impact of point-of-care ultrasound on the hospital length of stay for internal medicine inpatients with cardiopulmonary diagnosis at admission: study protocol of a randomized controlled trial-the IMFCU-1 (Internal Medicine Focused Clinical Ultrasound) study A bedside ultrasound sign ruling out pneumothorax in the critically ill. 5 Abnormalities were also observed on chest radiography, such as bilateral peripheral consolidation and ground-glass opacities, 6 as well with the use of lung ultrasound.
    keywords: acute; care; covid-19; failure; index; lung; patients; respiratory; type; ultrasound
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        item: #6786 of 7819
          id: cord-343330-wuzts3mt
      author: Ramos da Silva, S.
       title: Broad SARS-CoV-2 cell tropism and immunopathology in lung tissues from fatal COVID-19
        date: 2020-09-29
       words: 3454
      flesch: 40
     summary: Interpretation In lung tissues from severely affected COVID-19 patients, there is evidence for broad SARS-CoV-2 cell tropisms, activation of immune cells, and clearance of immunosuppressive cells, which could contribute to severe tissue damage, thromboemboli, excess inflammation and compromised adaptive immune responses. We searched PubMed up to 77 September 15, 2020 using the keywords coronavirus disease 2019, COVID-19, 78 SARS-CoV-2, cell tropism, cell markers, inflammation, interleukin 6, immune 79 response, immune suppression, immunofluorescence and immunohistochemistry, In lung tissues from severely affected COVID-19 patients, there is evidence for broad 107 SARS-CoV-2 cell tropisms, hyperactive immune cells, and clearance of immune cells 108 including immunosuppressive cells, which could contribute to severe tissue damage, 109 thromboemboli, excess inflammation and compromised adaptive immune responses.
    keywords: cells; color; covid-19; license; patients; preprint; sars
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        item: #6787 of 7819
          id: cord-343333-4krrmjio
      author: Salazar, Martín
       title: COVID-19, Hipertensión y Enfermedad cardiovascular
        date: 2020-06-18
       words: 2414
      flesch: 34
     summary: Al momento, se han registrado varios ensayos clínicos que evaluarán la acción de ARA y IECA sobre la evolución de la infección viral. De hecho, la elevación de la troponina y las anormalidades electrocardiográficas son hallazgos frecuentes.
    keywords: cardiovascular; con; cov-2; covid-19; enfermedad; los; más; pacientes; por; que; sars
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        item: #6788 of 7819
          id: cord-343357-5nhyumxl
      author: Heegaard, Peter M. H.
       title: Animal Models for COVID-19: More to the Picture Than ACE2, Rodents, Ferrets, and Non-human Primates. A Case for Porcine Respiratory Coronavirus and the Obese Ossabaw Pig
        date: 2020-09-25
       words: 3451
      flesch: 28
     summary: Impact of obesity and metabolic syndrome on immunity The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice Endocrine and metabolic link to coronavirus infection Problem pigs in a poke: a good pool of data Preliminary estimates of the prevalence of selected underlying health conditions among patients with coronavirus disease 2019 -United States Severe outcomes among patients with coronavirus disease 2019 (COVID-19) -United States Simulation of the clinical and pathological manifestations of coronavirus disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility Animal models of mechanisms of SARS-CoV-2 infection and COVID-19 pathology From mice to monkeys, animals studied for coronavirus answers The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade Further characterization of aminopeptidase-N as a receptor for coronaviruses Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 (COVID-19) in Wuhan, China: a retrospective study ACE2 receptor polymorphism: susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome A multibasic cleavage site in the spike protein of SARS-CoV-2 is essential for infection of human lung cells Altered pathogenesis of porcine respiratory coronavirus in pigs due to immunosuppressive effects of dexamethasone: implications for corticosteroid use in treatment of severe acute respiratory syndrome coronavirus Infection and rapid transmission of SARS-CoV-2 in ferrets Receptor recognition mechanisms of coronaviruses: a decade of structural studies Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS CoV-2 infection COVID-19: consider cytokine storm syndromes and immunosuppression Respiratory disease in rhesus macaques inoculated with SARS-CoV-2 SARS-CoV-2 infection in farmed minks, the Netherlands Porcine reproductive and respiratory syndrome virus-induced immunosuppression exacerbates the inflammatory response to porcine respiratory coronavirus in pigs Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York city area Immunosuppression for hyperinflammation in COVID-19: a double-edged sword? Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model Orosomucoid expression profiles in liver, adipose tissues and serum of lean and obese domestic pigs, Göttingen minipigs and Ossabaw minipigs Animal coronaviruses: what can they teach us about the severe acute respiratory syndrome? Cytokine storm in the lungs and inflammation are suggested as essential for the escalating and prolonged lung disease observed in severely affected COVID-19 patients, as is also the case for other severe human coronavirus infections like SARS and MERS (Mehta et al., 2020) .
    keywords: cov-2; covid-19; disease; et al; infection; sars
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        item: #6789 of 7819
          id: cord-343382-3pzvirdg
      author: Ierardi, Anna Maria
       title: Gastrointestinal Hemorrhages in Patients With COVID-19 Managed With Transarterial Embolization
        date: 2020-10-01
       words: 626
      flesch: 28
     summary: Heparin-related major bleeding in covid-19-positive patient: Perspective from the outbreak Spontaneous bleedings in COVID-19 patients: An emerging complication How to handle a COVID-19 patient in the angiographic suite Uncommon presentation of COVID-19: We describe the technical and clinical success as well as the safety profile of transarterial embolization (TAE) in the treatment of gastrointestinal (GI) bleedings in patients with COVID-19.
    keywords: bleeding; covid-19; patients
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        item: #6790 of 7819
          id: cord-343389-n276aksa
      author: Lades, Leonhard K.
       title: Daily emotional well‐being during the COVID‐19 pandemic
        date: 2020-06-23
       words: 3215
      flesch: 43
     summary: Drawing on the DRM, we estimated how affective experiences are associated with daily activities, time spent indoors/outdoors, and social interaction during the pandemic with a view to providing evidence to inform academic and policy debates on how the emotional consequences of self-isolation measures may be mitigated or exacerbated. Exercising (b = .46, SE = .07, p < .01), going for a walk (b = .33, SE = .06, p < .01), gardening (b = .29, SE = .09, p < .01), and pursuing a hobby (b = .23, SE = .09, p < .05) were ranked as the most enjoyable activities (see Table 1 ) and associated with the largest increase in positive affect in our within-person analyses (see Figure 1 ).
    keywords: activities; affect; interactions; people; time
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        item: #6791 of 7819
          id: cord-343414-2embihmf
      author: Wagner, Aaron B.
       title: Social distancing merely stabilized COVID‐19 in the US
        date: 2020-07-13
       words: 4244
      flesch: 54
     summary: We focus on the doubling rate, rather than R, because it can be more directly estimated from the time-series of confirmed cases and because it is more useful for making short-term predictions about confirmed case counts and hospital loads. These states have large numbers of confirmed cases, making the data from these states of higher quality.
    keywords: cases; covid-19; delay; doubling; intervention; number; rate; states; time
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        item: #6792 of 7819
          id: cord-343415-lj2trn85
      author: Del Barba, Paolo
       title: COVID‐19 cardiac involvement in a 38‐day old infant
        date: 2020-06-18
       words: 998
      flesch: 41
     summary: 1 COVID-19 may indeed have cardiac complications, including myocarditis, 2 and up to 31% of children have myocardial enzyme elevation, mainly creatine kinase MB, despite no specific sign or symptom of clinical cardiac disease. For the first time, we report the case of an infant affected by COVID-19 with documented mild cardiac involvement.
    keywords: cardiac; covid-19; involvement
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        item: #6793 of 7819
          id: cord-343422-910zswy0
      author: Bressy, Silvia
       title: Technological devices in COVID-19 primary care management: the Italian experience
        date: 2020-05-22
       words: 1258
      flesch: 41
     summary: In conclusion, primary health care plays a crucial role in the fight against coronavirus, therefore it should be reinforced, supported and constantly renewed. On the basis of our experience we can conclude that the technological support and the remote approach are essentials in COVID-19 primary care assessment and it would be advisable for everybody around the world to have up to date smartphone applications (that are cheap, easy to use and widespread also in resource limited settings (7)) or technological gadgets if medical tools are not easily available.
    keywords: care; covid-19; health; patients
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        item: #6794 of 7819
          id: cord-343449-4uxwojzo
      author: The Gibraltar COVID-19 Research Group Health Systems,
       title: Oxygen and mortality in COVID-19 pneumonia: a comparative analysis of supplemental oxygen policies and health outcomes across 26 countries.
        date: 2020-07-04
       words: 3916
      flesch: 44
     summary: Many nations seem to have implemented conservative oxygen strategies during the pandemic, effectively limiting the access of patients to supplemental oxygen. The Netherlands and Belarus were also excluded due to all three investigators failing to find clear national guidelines regarding oxygen targets.
    keywords: covid-19; guidelines; mortality; national; oxygen; patients; spo2; target
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        item: #6795 of 7819
          id: cord-343452-4m0ub9iv
      author: Barkama, Ravit
       title: Placenta-Derived Cell Therapy to Treat Patients With Respiratory Failure Due to Coronavirus Disease 2019
        date: 2020-09-15
       words: 4254
      flesch: 40
     summary: The majority of COVID-19 patients suffering from ARDS require invasive mechanical ventilation. Similar to other reports on MSCs (32), PLX-PAD is negative for both ACE2 and TMPRSS2; therefore, it can be safely used in COVID-19 patients without being a further target for SARS-CoV-2. PLX-PAD was administered via intramuscular injection.
    keywords: cells; covid-19; data; days; disease; mesenchymal; pad; patients; plx; stromal; treatment
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        item: #6796 of 7819
          id: cord-343472-fd34ls35
      author: Tersalvi, Gregorio
       title: Emerging evidence of myocardial injury in COVID-19: A path through the smoke
        date: 2020-08-02
       words: 970
      flesch: 35
     summary: Serum hs-cTnI level in risk stratification and the prediction of 30-day fatality in COVID-19 patients with no prior cardiovascular disease Prognostic implications of detectable cardiac troponin i below the 99th percentile in patients admitted to an emergency department without acute coronary syndrome The authors have declared that no competing interest exists. Given the accumulating evidence, a cardiac troponin assay should be included in the laboratory triage panel of patients with suspected of confirmed COVID-19, along with inflammatory and coagulation cascade activation markers (i.e. d-dimer), as it may help clinicians identify those who portend a higher risk of developing severe forms of the disease.
    keywords: covid-19; disease; patients
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        item: #6797 of 7819
          id: cord-343483-puly7tyv
      author: Pak, Jamie S.
       title: A Urology Department's Experience at the Epicenter of the COVID-19 Pandemic
        date: 2020-06-30
       words: 2381
      flesch: 44
     summary: The volume of COVID-19 patients was quickly increasing and many front-line providers were being quarantined for symptoms and/or exposure. As the ED-ICU gained prominence in the care pathway of COVID-19 patients at CUIMC, we also played an instrumental role in onboarding providers from other specialties to the attending/resident pair role.
    keywords: care; covid-19; department; icu; patients; resident; urology
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        item: #6798 of 7819
          id: cord-343490-94vkfrtw
      author: Handaya, Adeodatus Yuda
       title: Covid-19 mimicking symptoms in emergency gastrointestinal surgery cases during pandemic: a case series
        date: 2020-10-24
       words: 1407
      flesch: 45
     summary: All patients need to be examined for COVID-19, including in digestive surgery emergency cases. The COVID-19 pandemic has changed the ways patients are admitted and treated, including in emergency digestive surgery cases.
    keywords: case; covid-19; emergency; patient; surgery
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        item: #6799 of 7819
          id: cord-343502-1n0o4akm
      author: Chen, Zhang-Ren
       title: Pharmacotherapics Advice in Guidelines for COVID-19
        date: 2020-06-24
       words: 4070
      flesch: 36
     summary: To date, there is still no approved specific antiviral drug for COVID-19, and providing supportive care to help relieve symptoms is the most vital strategy for COVID-19 treatment. Chinese Guidelines recommended abidol for anti-COVID-19 treatment from the 6th edition.
    keywords: coronavirus; covid-19; guidelines; lopinavir; patients; ritonavir; sars; treatment
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        item: #6800 of 7819
          id: cord-343530-3fnfs2e5
      author: Leung, T.Y.
       title: Gender equity and public health outcomes: The COVID-19 experience
        date: 2020-05-21
       words: 2647
      flesch: 34
     summary: key: cord-343530-3fnfs2e5 authors: Leung, T.Y.; Sharma, Piyush; Adithipyangkul, Pattarin; Hosie, Peter title: Gender equity and public health outcomes: The COVID-19 experience date: 2020-05-21 journal: J Bus Res DOI: 10.1016/j.jbusres.2020.05.031 sha: doc_id: 343530 cord_uid: 3fnfs2e5 This paper extends the growing research on the impact of gender equity on public health outcomes using the ongoing Covid-19 pandemic as its research setting. The results provide useful insights about the factors that influence the representation of women in political systems around the world and its impact on public health outcomes.
    keywords: covid-19; gender; health; impact; outcomes; population; public; women
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        item: #6801 of 7819
          id: cord-343535-r8rsbfs3
      author: Chowdhury, Mohammad Asaduzzaman
       title: Prospect of biobased antiviral face mask to limit the coronavirus outbreak
        date: 2020-10-03
       words: 2320
      flesch: 52
     summary: It has been reported that face masks are effective in lowering the spread of the virus. Face masks can filter droplets containing the virus.
    keywords: covid-19; face; licorice; mask; root; spread; virus
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        item: #6802 of 7819
          id: cord-343545-ga56ozp3
      author: Pablos, J. L.
       title: Clinical Outcomes of Patients with COVID-19 and Chronic Inflammatory and Autoimmune Rheumatic Diseases: A Multicentric Matched-Cohort Study
        date: 2020-06-20
       words: 3866
      flesch: 42
     summary: Rheumatic diseases were IA (60%) and AI/IMID (40%). We performed a retrospective observational matched-cohort study from the databases of five reference centres pertaining to a public research network for the investigation of inflammation and rheumatic diseases (RIER, https://red-rier.org/).
    keywords: cohort; covid-19; disease; imid; medrxiv; patients; preprint; risk
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        item: #6803 of 7819
          id: cord-343553-07c9ec2b
      author: Radfar, S. R.
       title: Reorganization of Substance Use Treatment and Harm Reduction Services during the COVID-19 Pandemic: A Global Survey
        date: 2020-09-22
       words: 6528
      flesch: 37
     summary: According to the responses, in all three groups of income countries treatment and/or harm reduction services for pregnant women were a group with minimum impact from COVID-19. The World Drug Report 2020 stated that, If Governments respond the same way to the current economic slump, interventions such as prevention of drug use and related risk behaviors and drug treatment services could be hard hit (Nations, 2020) .
    keywords: countries; covid-19; harm; health; income; license; medrxiv; pandemic; preprint; reduction; respondents; services; treatment; use
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        item: #6804 of 7819
          id: cord-343559-kjuc3nqa
      author: Asiamah, Nestor
       title: Short-Term Changes in Behaviors Resulting from COVID-19-Related Social Isolation and Their Influences on Mental Health in Ghana
        date: 2020-10-08
       words: 6028
      flesch: 47
     summary: This study assessed the behavioral outcomes of Coronavirus 2019 (COVID-19) social distancing protocols and their influences on mental health. An increase in sedentary behavior had a negative influence on mental health.
    keywords: behaviors; changes; covid-19; frequency; health; isolation; lockdown; study; survey
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        item: #6805 of 7819
          id: cord-343566-epvswt7f
      author: Wang, Zhao-Hua
       title: Critically Ill Patients with Coronavirus Disease 2019 in a Designated ICU: Clinical Features and Predictors for Mortality
        date: 2020-07-20
       words: 3295
      flesch: 47
     summary: Several previous descriptive cohort studies have reported epidemiological, demographic, and clinical characteristics of COVID-19 patients, as well as severe cases. SARS-CoV-2 could also cause myocardial injury, as assessed by increased troponin I level accompanying increased cardiovascular symptoms in COVID-19 patients.
    keywords: covid-19; data; hospital; mortality; patients; sars; sofa; study; survivors
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        item: #6806 of 7819
          id: cord-343589-9okzwtci
      author: Mantero, Vittorio
       title: Assessing the susceptibility to acute respiratory illness COVID-19-related in a cohort of multiple sclerosis patients
        date: 2020-08-19
       words: 2210
      flesch: 45
     summary: The prevalence of COVID-19 within MS patients seems to resemble the prevalence in general population. In our cohort, the incidence of clinical presentations suggestive for COVID-19 infection (5.4%) and the incidence of confirmed cases among MS patients (0.3%) does not seem to differ meaningfully from the general population.
    keywords: covid-19; infection; patients; suspect
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        item: #6807 of 7819
          id: cord-343601-po9br5zm
      author: Wang, Gan-Yi
       title: Perceived psychosocial health and its sociodemographic correlates in times of the COVID-19 pandemic: a community-based online study in China
        date: 2020-10-26
       words: 4766
      flesch: 40
     summary: However, the findings are still mixed, and the use of different domains of mental health and their measurement techniques make their generalization and contextual interpretation challenging for scholars. In this study, we adopted a tactical approach to capture three core domains of mental health that are more likely to occur during the pandemic and relate them to several proximal and distal factors to understand the relative contrasting contribution to each of the three constructs. prevalence of COVID-19 on April 1, 2020, the top two provinces and lower one province based on the number of cases were selected from each region.
    keywords: china; covid-19; depression; health; hopelessness; loneliness; pandemic; population; survey
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        item: #6808 of 7819
          id: cord-343618-jjb8da4a
      author: Nie, Kai
       title: Gastrointestinal insights during the COVID-19 epidemic
        date: 2020-09-26
       words: 2049
      flesch: 37
     summary: Although respiratory symptoms are the main complication in COVID-19 patients, the disease is also associated with gastrointestinal problems, with diarrhea, nausea, and vomiting being primary COVID-19 symptoms. Clinically, COVID-19 patients frequently present with gastrointestinal symptoms, including diarrhea, nausea, and vomiting.
    keywords: coronavirus; cov-2; covid-19; patients; sars; stool
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        item: #6809 of 7819
          id: cord-343619-vk3p72ze
      author: Vaish, Abhishek
       title: COVID‑19: Current Knowledge and Best Practices for Orthopaedic Surgeons
        date: 2020-07-02
       words: 556
      flesch: 47
     summary: This crisis has perhaps completed the evolution cycle and we have seen a paradigm shift in revisiting conservative management of various orthopaedic problems and fracture management [3] . COVID-19: Current knowledge and best practices for orthopaedic surgeons COVID-19 and Orthopaedic surgeon: The Indian scenario Revisiting conservative orthopaedic management of fractures during COVID-19 pandemic COVID-19 and remote consulting strategies in the management of trauma and orthopaedics Post COVID-19: Planning strategies to resume orthopaedic surgery-challenges and considerations Unprecedented surge in publications related to COVID-19 in the first three months of pandemic The authors have interestingly used the reference of 'Ikigai', which is a Japanese secret to a long and happy life.
    keywords: authors; covid-19
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        item: #6810 of 7819
          id: cord-343622-5270vdkr
      author: Bowman, Deborah
       title: American Society for Gastrointestinal Endoscopy: Guidance for trainees during the COVID-19 pandemic
        date: 2020-05-30
       words: 3141
      flesch: 32
     summary: It is important to approach these discussions empathically and acknowledge the personal, physical, and economic stresses that disproportionately affect trainees as a result of this pandemic, and to listen and act upon trainee concerns when possible. In addition, many fellows cannot interview at all their desired programs because they cannot always find coverage for their absences.
    keywords: acgme; covid-19; fellows; pandemic; practice; program; residents; trainees; training
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        item: #6811 of 7819
          id: cord-343637-3g4tosjx
      author: Tumlinson, Anne
       title: Post‐Acute Care Preparedness in a COVID‐19 World
        date: 2020-05-21
       words: 2845
      flesch: 38
     summary: Post-acute care includes long-term acute care hospitals (LTACHs) that provide hospital-level care for medically complex patients; inpatient rehabilitation facilities (IRFs) that provide hospital-level intense medical rehabilitation focused on restoring functional independence for individuals with disabilities resulting from an injury, illness, or medical condition; skilled nursing facilities (SNFs) that provide skilled nursing, medical management, and therapy services to individuals who do not require services provided in a hospital; and home health agencies (HHAs) that provide skilled care delivered by healthcare professionals in the patient's home for the treatment of a medical condition, illness, or disability. We have adapted their framework to reflect the realm of post-acute care:
    keywords: acute; care; covid-19; health; hospital; patients; providers
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        item: #6812 of 7819
          id: cord-343643-if04rgzi
      author: Hirko, Kelly A
       title: Telehealth in Response to the Covid-19 Pandemic: Implications for Rural Health Disparities
        date: 2020-06-26
       words: 1925
      flesch: 30
     summary: [12] Despite these challenges, rural health systems and providers have responded to a rapidly evolving crisis. Given the substantial investment in infrastructure and training, rural health systems should also consider a comprehensive strategy to ensure sustainability of telehealth programs following the COVID-19 pandemic, which needs to include lobbying for continuing third-party reimbursement for these services.
    keywords: access; covid-19; pandemic; rural; telehealth
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        item: #6813 of 7819
          id: cord-343684-z63qn66b
      author: Serge, Rozenberg
       title: Are we equal in adversity? Does Covid-19 affect women and men differently?
        date: 2020-05-15
       words: 4470
      flesch: 53
     summary: An even higher proportion of men were admitted to the ICU (76.5% vs 33.5%), while more women were being discharged and more men died in each age class. Similarly, in the Seattle and New York areas more men (63% and 76%) were admitted to the J o u r n a l P r e -p r o o f ICU (27, 35) .
    keywords: countries; covid-19; data; disease; men; patients; sex; women
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        item: #6814 of 7819
          id: cord-343688-g6bevqxq
      author: Ahundjanov, B. B.
       title: Power Law in COVID-19 Cases in China
        date: 2020-07-27
       words: 5605
      flesch: 56
     summary: An interesting aspect of power law distribution is that it is the macro-level steady-state phenomenon that, in theory, can arise from a micro-level random proportionate growth process, known as Gibrat's law (Gibrat, 1931) , 2 whereby each unit's (e.g., city's) growth rate is drawn randomly and independently of its current size. Gabaix and Ibragimov (2011) proposed 'rank -1/2' test to verify the goodness-of-fit of power law distribution.
    keywords: cases; covid-19; distribution; law; license; power; preprint
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        item: #6815 of 7819
          id: cord-343691-sjz5og78
      author: Nakajima, Kei
       title: Serious Conditions in COVID-19 Accompanied With a Feature of Metabolic Syndrome
        date: 2020-05-08
       words: 1225
      flesch: 37
     summary: Obesity (Silver Spring) Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission Risk of COVID-19 for patients with obesity Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics COVID-19 pandemic, coronaviruses, and diabetes mellitus COVID-19 in patients with diabetes: risk factors that increase morbidity Diabetes in COVID-19: Prevalence, pathophysiology, prognosis and practical considerations COVID-19 and diabetes: Knowledge in progress Are patients with hypertension and diabetes mellitus at increased risk for COV-ID-19 infection? Coronavirus Infections and Type 2 Diabetes-Shared Pathways with Therapeutic Implications High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement A possible association between suspected restrictive pattern as assessed by ordinary pulmonary function test and the metabolic syndrome Association between low pulmonary function and metabolic risk factors in Korean adults: the Korean National Health and Nutrition Survey Relationships of decreased lung function with metabolic syndrome and obstructive sleep apnea in Japanese males Prediabetes and impaired lung function in asymptomatic adults Lung function changes in older people with metabolic syndrome and diabetes Association of restrictive ventilatory dysfunction with the development of prediabetes and type 2 diabetes in Koreans The vital capacity is vital: epidemiology and clinical significance of the restrictive spirometry pattern Metabolic syndrome as an independent risk factor of hypoxaemia in influenza A (H1N1) 2009 pandemic Morbid obesity as a risk factor for hospitalization and death due to 2009 pandemic influenza A(H1N1) disease High body mass index as a risk factor for hospitalization due to influenza: a case-control study Is a single definition of the metabolic syndrome appropriate? In recent decades, many investigators have convincingly shown that people with obesity, prediabetes, diabetes and MetS are at increased risk for impaired lung function, and especially impaired restrictive lung pattern [16] [17] [18]
    keywords: covid-19; diabetes; mets; obesity
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        item: #6816 of 7819
          id: cord-343712-gn7fw891
      author: Taglauer, Elizabeth
       title: Consistent localization of SARS-CoV-2 spike glycoprotein and ACE2 over TMPRSS2 predominance in placental villi of 15 COVID-19 positive maternal-fetal dyads
        date: 2020-08-25
       words: 1498
      flesch: 20
     summary: We also found a statistically significant reduction in ACE2 expression 150 levels in COVID-19 Maternal placental tissues as compared to controls, (Fig. 3B) , but this finding Map, COVID-19 Map Clinical features and obstetric and neonatal outcomes of pregnant 221 patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study, The 222 Clinical characteristics and intrauterine vertical transmission 226 potential of COVID-19 infection in nine pregnant women: a retrospective review of medical 227 records A systematic scoping review of 231 COVID-19 during pregnancy and childbirth, International journal of gynaecology and obstetrics: 232 the official organ of the International Federation of COVID-19 and newborn health: systematic review Rates of 240 Maternal and Perinatal Mortality and Vertical Transmission in Pregnancies Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Co-V-2) Infection: A Systematic 242 Review Antibodies in Infants Born to 245 Mothers With COVID-19 Pneumonia The unique immunological and microbial aspects of 297 pregnancy Vertical transmission of COVID-19: SARS-CoV-2 RNA on the fetal side of 301 the placenta in pregnancies with COVID-19 positive mothers and neonates at birth Detection of SARS-COV-2 in Placental and Fetal Membrane Samples SARS-CoV-2 infection of the placenta Visualization of severe acute respiratory syndrome coronavirus 2 318 invading the human placenta using electron microscopy Placental 322 Pathology in COVID-19 Placental Pathology in Covid-19 Positive Mothers: Preliminary Pediatric and developmental pathology : the official journal of the Society for Pediatric 326 Pathology and the Hepatitis C 330 Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of 331 Maternal NK Cells: Potential Implications for Limiting Vertical Transmission Placental 130 pathology diagnoses, listed in Table 2 , were notable for the presence of fibrin deposition and 131 signs of inflammation in COVID-19 Maternal placentas, however this did not meet statistical 132 significance.
    keywords: cov-2; covid-19; placental; sars
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        item: #6817 of 7819
          id: cord-343715-y594iewi
      author: Gavriatopoulou, Maria
       title: Organ-specific manifestations of COVID-19 infection
        date: 2020-07-27
       words: 8776
      flesch: 34
     summary: Cerebrovascular disease represents another mechanism explaining neurological signs and symptoms in COVID-19 patients, although the rate of acute stroke admissions has been significantly reduced over the COVID-19 pandemic [125] . Among COVID-19 patients who suffered a stroke, the rate of cryptogenic and embolic strokes was higher, and events were more severe and affected younger patients [126, 129] .
    keywords: ace2; acute; cells; china; coronavirus; cov-2; covid-19; disease; infection; injury; manifestations; patients; pneumonia; sars; study; symptoms; syndrome
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        item: #6818 of 7819
          id: cord-343739-t3z6ghyp
      author: Conforti, Claudio
       title: Management of advanced melanoma in the COVID‐19 era
        date: 2020-05-14
       words: 222
      flesch: 27
     summary: A call for action Oncology practice during the COVID-19 pandemic Infezione da Coronavirus: Vademecum per i pazienti affetti da psoriasi cutanea e/o artropatia psoriasica AIOM, Rischio infettivo da Coronavirus Covid-19: indicazioni per l'oncologia Cancer patient management during the covid-19 pandemic 2 Apart from psoriasis, which can sometimes also be treated in an alternative way, we must focus our attention on the most fragile patients in dermatology, that is, oncologic patients suffering from advanced melanoma.
    keywords: covid-19
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        item: #6819 of 7819
          id: cord-343740-vcys2q2t
      author: Kawachi, Ichiro
       title: COVID-19 and the ‘rediscovery’ of health inequities
        date: 2020-09-24
       words: 2376
      flesch: 47
     summary: When future historians look back on the dismal performance of unequal societies during the Covid-19 pandemic, they will conclude that their leaders were too slow to implement public health measures, and too hasty in loosening them. Likewise, health inequalities have been evident since the beginning of public record keeping-q.v.
    keywords: covid-19; health; infection; pandemic; people; usa; work
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        item: #6820 of 7819
          id: cord-343743-6k3soh1l
      author: Chaudhary, Sachin
       title: Antifibrotics in COVID-19 Lung Disease: Let Us Stay Focused
        date: 2020-09-09
       words: 3353
      flesch: 34
     summary: Health Qual Life Outcomes Correlation between pneumonia severity and pulmonary complications in middle east respiratory syndrome Follow-up chest radiographic findings in patients with MERS-CoV after recovery Histopathology of Middle East respiratory syndrome coronovirus (MERS-CoV) infection -clinicopathological and ultrastructural study The 1-year impact of severe acute respiratory syndrome on pulmonary function, exercise capacity, and quality of life in a cohort of survivors The longterm impact of severe acute respiratory syndrome on pulmonary function, exercise capacity and health status Follow-up study on pulmonary function and lung radiographic changes in rehabilitating severe acute respiratory syndrome patients after discharge Pulmonary sequelae in convalescent patients after severe acute respiratory syndrome: evaluation with thin-section CT Long-term bone and lung consequences associated with hospital-acquired severe acute respiratory syndrome: a 15-year follow-up from a prospective cohort study Pathology and pathogenesis of severe acute respiratory syndrome Abnormal pulmonary function in COVID-19 patients at time of hospital discharge Clinical features of patients infected with 2019 novel coronavirus in Wuhan COVID-19 pneumonia: different respiratory treatments for different phenotypes? Now, months since the initial description in Wuhan, China, with almost 10 million infected worldwide and about half a million deaths, the clinical and the scientific communities have learned much and pivoted to high-quality evidence for the management of COVID-19 patients.
    keywords: ards; covid-19; fibrosis; lung; patients; pulmonary; survivors; syndrome
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        item: #6821 of 7819
          id: cord-343759-me0n2k3f
      author: Majiya, H.
       title: Seroprevalence of COVID-19 in Niger State
        date: 2020-08-05
       words: 4950
      flesch: 53
     summary: https://doi.org/10.1101/2020.08.04.20168112 doi: medRxiv preprint COVID-19 seroprevalence among age groups, gender and by occupation varied widely ( Figure 6 ). https://doi.org/10.1101/2020.08.04.20168112 doi: medRxiv preprint Real estimates of mortality following COVID-19 infection.
    keywords: covid-19; license; medrxiv; niger; participants; preprint; state
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        item: #6822 of 7819
          id: cord-343766-hlg7t5i5
      author: Vinken, Mathieu
       title: A putative AOP for pneumonia related to COVID-19
        date: 2020-07-20
       words: 996
      flesch: 33
     summary: Liver injury in COVID-19: the current evidence Adverse outcome pathways: a conceptual framework to support ecotoxicology research and risk assessment Increasing scientific confidence in adverse outcome pathways: application of tailored Bradford-Hill considerations for evaluating weight of evidence Harnessing the power of novel animal-free test methods for the development of COVID-19 drugs and vaccines Chest computed tomography findings of coronavirus disease 2019 (COVID-19) pneumonia Severe acute lung injury related to COVID-19 infection: a review and the possible role for escin A putative AOP for pneumonia linked to COVID-19 Facing COVID-19 in the ICU: vascular dysfunction, thrombosis, and dysregulated inflammation COVID-19 infection and oxidative stress: an under-explored approach for prevention and treatment? The future COVID-19 AOP network could also cover the different steps of virus infection and, especially, replication, now captured in a single KE.
    keywords: aop; covid-19
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        item: #6823 of 7819
          id: cord-343773-9f7ew8uj
      author: Volo, T.
       title: Elective tracheostomy during COVID-19 outbreak: to whom, when, how? Early experience from Venice, Italy
        date: 2020-07-12
       words: 3626
      flesch: 47
     summary: The need for prolonged invasive mechanical ventilation in COVID-19 patients is placing the otorhinolaryngologist in front of an increasing request for tracheostomy. The mortality rate of COVID-19 patients admitted to ICU that underwent tracheostomy was 18%.
    keywords: covid-19; days; dimer; patients; risk; sofa; study; tracheostomy
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        item: #6824 of 7819
          id: cord-343797-kpmz5kwg
      author: Lee, Martin Beng‐Huat
       title: GOING TO WAR ON COVID19: MOBILIZING AN ACADEMIC NEPHROLOGY GROUP PRACTICE
        date: 2020-07-04
       words: 2877
      flesch: 40
     summary: Doctors could also be re-deployed to the emergency department and hospital pandemic ward teams to care for COVID-19 patients. In ICU, continuous renal replacement therapy (CRRT) and sustained low efficiency dialysis (SLED) for COVID-19 patients was performed using dedicated machines.
    keywords: care; covid-19; dialysis; disease; hospital; nephrology; patients
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        item: #6825 of 7819
          id: cord-343818-pj1oludh
      author: Liu, Chan
       title: Children with COVID-19 behaving milder may challenge the public policies: a systematic review and meta-analysis
        date: 2020-09-01
       words: 4852
      flesch: 44
     summary: Note: a Vulnerable children include children who are supported by social care, those with safeguarding and welfare needs, including child in need plans, on child protection plans, 'looked after' children, young carers, disabled children and those with education, health and care (EHC) plans b Other open child care programs are home-based child care, pre-kindergarten programs, Head Start and Early Head Start programs, temporary child care centers, and child care centers that partner with healthcare facilities to support healthcare workers who need child care Fever and cough are the most common symptoms in COVID-19 children, in our study, the pooled incidence of fever is 52.7%, which is lower than that in adults [41] , SARS [7, 42] and influenza
    keywords: analysis; cases; children; clinical; coronavirus; cov-2; covid-19; disease; sars; studies
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        item: #6826 of 7819
          id: cord-343819-1uki4b3d
      author: Mian, Muhammad S
       title: Pathological Findings and Management of COVID-19 Patients: A Brief Overview of Modern-day Pandemic
        date: 2020-05-15
       words: 4661
      flesch: 46
     summary: Two drugs, remdesevir and chloroquine, have shown some good results, but it is too soon to state their efficacy as there is limited data on the effectiveness of these drugs in COVID-19 patients. In this review article, we aim to identify and highlight clinical features, pathological and radiological findings, and possible treatment options for COVID-19 patients and to organize the little information we have on this pathogen.
    keywords: coronavirus; covid-19; disease; findings; patients; pneumonia; symptoms; treatment
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        item: #6827 of 7819
          id: cord-343822-k00ng5nl
      author: Hoekman, Lieke Michaela
       title: The Dutch COVID-19 approach: Regional differences in a small country.: The Dutch COVID-19 approach.
        date: 2020-08-27
       words: 6126
      flesch: 55
     summary: Apart from COVID-19 testing policies, as of early April, additional serology tests were done by the blood bank which provided insight into the spread of the virus among the population. Data on COVID-19 patients is collected similarly in the same health system, which offers a unique opportunity to compare variation in COVID-19 health data, keeping many external factors constant.
    keywords: containment; country; covid-19; dutch; government; health; measures; netherlands; number; policy; regional; testing; virus
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        item: #6828 of 7819
          id: cord-343845-suoy3ojr
      author: Martín, Vicente
       title: Prevalencia de la Infección por SARS-CoV-2 en médicos y enfermeras de Atención Primaria y Residencias de Ancianos del Área de Salud de León y Factores asociados
        date: 2020-06-06
       words: 2714
      flesch: 45
     summary: RESUMEN Objetivo: Evaluar la prevalencia y los factores asociados a la infección por SARS-CoV-2 en médicos y enfermeras de centros de atención primaria y residencias de ancianos del área de salud de León (España). J o u r n a l P r e -p r o o f RESUMEN Objetivo: Evaluar la prevalencia y los factores asociados a la infección por SARS-CoV-2 en médicos y enfermeras de centros de atención primaria y residencias de ancianos del área de salud de León (España).
    keywords: cov-2; infección; infection; por; sars
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        item: #6829 of 7819
          id: cord-343864-0258nh92
      author: Straughn, Alex R.
       title: Withaferin A: a potential therapeutic agent against COVID-19 infection
        date: 2020-07-19
       words: 2922
      flesch: 39
     summary: Patients with Cancer appear more vulnerable to SARS-COV-2: a multicenter study during the COVID-19 outbreak Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Case fatality rate of Cancer patients with COVID-19 in a New York hospital system Clinical characteristics of COVID-19-infected cancer patients: a retrospective case study in three hospitals within Wuhan Estimating clinical severity of COVID-19 from the transmission dynamics in Wuhan, China Disruptions in Cancer Care in the Era of COVID-19 Coronavirus disease-2019 in cancer patients. One such comorbidity is the presence of an oncological malignancy, with cancer patients exhibiting an approximate two-fold increase in mortality rate.
    keywords: ace2; cancer; cells; cov-2; covid-19; patients; sars; wfa
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        item: #6830 of 7819
          id: cord-343870-g2v7ihud
      author: Liu, Wei
       title: Virus-, host-, immune-based targets for COVID-19 therapy
        date: 2020-10-06
       words: 1721
      flesch: 40
     summary: Including SARS-CoV-2, till-date, there are seven potential viral strains of Coronaviridae family have invaded the Sapiens that include: Anti-viral agents against different targets had exhibited profound therapeutic effect on SARS-CoV-2 through which the clinicians were able to control the COVID-19 outbreak.
    keywords: cov-2; covid-19; host; replication; sars
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        item: #6831 of 7819
          id: cord-343876-2inr4mcy
      author: Xie, Qin
       title: COVID-19 patients managed in psychiatric inpatient settings due to first-episode mental disorders in Wuhan, China: clinical characteristics, treatments, outcomes, and our experiences
        date: 2020-10-02
       words: 4839
      flesch: 35
     summary: Because COVID-19 patients with new onset of mental disorders are different from psychiatric patients infected with SARS-CoV-2 and most COVID-19 patients in real-world clinical practice have no mental disorders before the infection, we did not include SARS-CoV-2-infected psychiatric patients as subjects. During the outbreak of COVID-19, the selection of an appropriate treatment setting for COVID-19 patients with mental disorders is a dilemma: in respiratory treatment settings these patients are more likely to not adhere with The main findings of this comparative study are 1) adjustment disorder and acute and transient psychotic disorders, with associated acute stress were the main clinical diagnoses in the COVID-19 group and some other disorders had their organic basis such as delirium due to infection and chloroquine-induced psychosis, while serious mental illnesses (SMIs) and alcohol use disorders were overrepresented in the control group, a common feature of inpatients of most Chinese psychiatric hospitals; 2) a wide range of psychiatric symptoms were found in COVID-19 patients with mental disorders on admission, including psychotic symptoms, aggressive behaviors, and anxiety symptoms; 3) the most common respiratory symptom of COVID-19 patients was cough, followed by fever, chills, and fatigue; and 4) mental disorders and COVID-19 of most patients were successfully treated after symptomatic and supportive treatments, including conventional psychotropic treatment and antiviral treatment, and, COVID-19 patients left the hospital earlier than psychiatric patients without COVID-19, on average by 16 days after admission.
    keywords: covid-19; covid-19 patients; disorders; group; hospital; patients; psychiatric; symptoms; treatment
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        item: #6832 of 7819
          id: cord-343877-jzkaee16
      author: Newdick, Chris
       title: Tragic choices in intensive care during the COVID-19 pandemic: on fairness, consistency and community
        date: 2020-08-07
       words: 5266
      flesch: 47
     summary: Public authorities have wide discretion in making resource allocation decisions. We have sought to clarify for clinicians and front-line workers a framework which echoes in many respects the ethical frameworks developed for CCG resource allocation decisions more broadly, and which, subject to certain constraints and formalised processes, the law has accommodated.
    keywords: care; community; consistency; decision; individual; making; patients; rights
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        item: #6833 of 7819
          id: cord-343881-0i3rfpvd
      author: Norton, Alice
       title: The remaining unknowns: a mixed methods study of the current and global health research priorities for COVID-19
        date: 2020-07-29
       words: 3617
      flesch: 45
     summary: Recognising that this survey inherently focused respondents on the existing WHO priority framework, we expanded our consultation through workshops to enable broader discussions of research priorities. Analysing the data from the workshops allowed a further open consideration of current research priorities as this step expanded beyond the limitation that the survey had of asking questions within the framework of the WHO roadmap.
    keywords: data; global; health; pandemic; priorities; research; roadmap; survey
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        item: #6834 of 7819
          id: cord-343917-67qjqxqh
      author: Dabrowska, Dominika
       title: Staying Ahead of the Curve: Modified Approach to Emergency Caesarean Section Under General Anaesthesia in COVID-19 Pandemic
        date: 2020-04-30
       words: 3444
      flesch: 41
     summary: The aim of this review is to highlight the key recommendations related to obstetric anaesthesia from scientific bodies in the United Kingdom and United States and to summarize recently developed and implemented clinical pathways for care of obstetric patients – specifically those requiring urgent general anaesthesia for caesarean section within a large maternity unit in London. The key messages of this guidance are as follows: -COVID-19 diagnosis itself is not considered a contraindication for neuraxial anaesthesia -Early epidural analgesia may reduce the need for general anaesthesia for emergent caesarean delivery -All healthcare workers should implement droplet and contact precautions -Since the care of COVID-19 patients is time intensive, additional staffing may be needed and back-up strategies may need to be developed.
    keywords: anaesthesia; covid-19; delivery; general; intubation; patients; team; theatre
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        item: #6835 of 7819
          id: cord-343919-n8884bli
      author: Salvio, Gianmaria
       title: Bone Metabolism in SARS-CoV-2 Disease: Possible Osteoimmunology and Gender Implications
        date: 2020-09-01
       words: 3912
      flesch: 33
     summary: Even though the available data are limited, the RANK-RANKL system may provide the best therapeutic target to prevent bone resorption after COVID-19 disease. In contrast, other researchers have described leukopenia, rather than leukocytosis, as a common finding in patients with severe COVID-19 disease [11] [12]
    keywords: bone; cells; covid-19; disease; infection; patients; rankl; sars; system; vitamin
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        item: #6836 of 7819
          id: cord-343926-47m17k1t
      author: Kuzemko, Caroline
       title: Covid-19 and the Politics of Sustainable Energy Transitions
        date: 2020-07-02
       words: 6628
      flesch: 45
     summary: Unsurprisingly, therefore, the early implications of Covid-19 were also significant but varied for emissions, fossil fuel and sustainable energy. This aspect of the politics of sustainable energy becomes particularly relevant given that lockdown led to, more or less temporary, new social practices.
    keywords: change; covid-19; demand; energy; fossil; fuel; global; pandemic; politics; recovery; term; time; transitions
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        item: #6837 of 7819
          id: cord-343927-s54n1cmn
      author: Sayad, Babak
       title: Leukocytosis and alteration of hemoglobin level in patients with severe COVID‐19: Association of leukocytosis with mortality
        date: 2020-10-14
       words: 637
      flesch: 53
     summary: In severely affected patients with COVID-19, leukocytosis was more prevalent as it was observed in11.4% severe COVID-19 patients compared to 4.8% in patients with mild to moderate disease. ACE2 the Janus-faced protein -from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19 Hemoglobin value may be decreased in patients with severe coronavirus disease 2019 COVID-19 and the clinical hematology laboratory Abnormalities of peripheral blood system in patients with COVID-19 in Wenzhou, China Towards an artificial intelligence framework for data-driven prediction of coronavirus clinical severity Leukocytosis and alteration of hemoglobin level in patients with severe COVID-19:
    keywords: patients
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        item: #6838 of 7819
          id: cord-343929-9ebw3x8r
      author: Gupta, Ritesh
       title: Clinical considerations in patients with diabetes during times of COVID19: An update on lifestyle factors and antihyperglycemic drugs with focus on India
        date: 2020-09-08
       words: 1927
      flesch: 36
     summary: Diabetes Ther Early treatment of COVID-19 patients with hydroxychloroquine and azithromycin: A retrospective analysis of 1061 cases in Marseille, France Efficacy and Safety of Anti-malarial Drugs (Chloroquine and Hydroxy-Chloroquine) in Treatment of COVID-19 Infection: A Systematic Review and Meta-Analysis. A review Vitamin D deficiency and co-morbidities in COVID-19 patients -A fatal relationship?
    keywords: control; covid-19; diabetes; india; patients
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        item: #6839 of 7819
          id: cord-343969-9nec3lj8
      author: Otugo, Onyeka
       title: COVID-19: The Additional Sentence for the Incarcerated
        date: 2020-09-30
       words: 1750
      flesch: 41
     summary: Some individuals and organizations advocate for a mandatory release of the incarcerated who are not deemed a risk to the general population, whereas others advocate for improving health care in jails and prisons. 22 To do no harm to this disenfranchised population, the first step is recognizing that there is a problem with health care in correctional facilities.
    keywords: care; health; people; population; prisons
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        item: #6840 of 7819
          id: cord-343970-anocx4y1
      author: Bansal, Rashika
       title: Metabolic Syndrome and COVID 19: Endocrine-Immune-Vascular Interactions Shapes Clinical Course
        date: 2020-06-30
       words: 6538
      flesch: 33
     summary: ACE2 is expressed in pancreatic islets, vascular endothelium, and adipose tissue, and the SARS-CoV-2 -ACE2 interaction in these tissues, along with other factors, govern the spectrum and the severity of clinical manifestations among COVID-19 patients with metabolic syndrome. This review describes the spectrum of clinical features, the likely pathophysiologic mechanisms and potential implications for the management of metabolic syndrome in COVID-19 patients.
    keywords: ace2; angiotensin; cell; coronavirus; cov-2; covid-19; diabetes; disease; infection; inflammatory; obesity; patients; risk; sars; type
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        item: #6841 of 7819
          id: cord-343973-n5ogyxz7
      author: Ip, Andrew
       title: Hydroxychloroquine and tocilizumab therapy in COVID-19 patients—An observational study
        date: 2020-08-13
       words: 4336
      flesch: 40
     summary: key: cord-343973-n5ogyxz7 authors: Ip, Andrew; Berry, Donald A.; Hansen, Eric; Goy, Andre H.; Pecora, Andrew L.; Sinclaire, Brittany A.; Bednarz, Urszula; Marafelias, Michael; Berry, Scott M.; Berry, Nicholas S.; Mathura, Shivam; Sawczuk, Ihor S.; Biran, Noa; Go, Ronaldo C.; Sperber, Steven; Piwoz, Julia A.; Balani, Bindu; Cicogna, Cristina; Sebti, Rani; Zuckerman, Jerry; Rose, Keith M.; Tank, Lisa; Jacobs, Laurie G.; Korcak, Jason; Timmapuri, Sarah L.; Underwood, Joseph P.; Sugalski, Gregory; Barsky, Carol; Varga, Daniel W.; Asif, Arif; Landolfi, Joseph C.; Goldberg, Stuart L. title: Hydroxychloroquine and tocilizumab therapy in COVID-19 patients—An observational study date: 2020-08-13 journal: PLoS One DOI: 10.1371/journal.pone.0237693 sha: doc_id: 343973 cord_uid: n5ogyxz7 Hydroxychloroquine has been touted as a potential COVID-19 treatment. This retrospective observational cohort study of 2512 hospitalized COVID-19 patients within a 13-hospital network did not find the empirical use of hydroxychloroquine with or without co-treatment with azithromycin to be associated with a reduction in mortality (adjusted HR, 0.99 for any hydroxychloroquine during hospitalization
    keywords: azithromycin; covid-19; drug; hospital; hydroxychloroquine; observational; patients; study; tocilizumab; treatment
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        item: #6842 of 7819
          id: cord-343978-w1fsu787
      author: Greene, E A
       title: Extension Horses, Inc. experts act fast to create online resources to assist the horse industry during COVID-19
        date: 2020-06-24
       words: 4263
      flesch: 49
     summary: Over 85% of survey respondents had a high level of satisfaction with using a web-based platform, and 88% of respondents were highly likely to recommend future EH webinars to others, with 12% moderately likely to recommend future EH webinars. Live webinar participants were invited to participate in several polls during the webinar and were sent a brief survey to complete at the end of the webinar series.
    keywords: c r; covid-19; equine; s c; webinar
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        item: #6843 of 7819
          id: cord-343981-m6z9aqvu
      author: Freedberg, Daniel E.
       title: Famotidine Use is Associated with Improved Clinical Outcomes in Hospitalized COVID-19 Patients: A Propensity Score Matched Retrospective Cohort Study
        date: 2020-05-22
       words: 1283
      flesch: 40
     summary: This retrospective study found that, in patients hospitalized with COVID-19, famotidine use was associated with a reduced risk of clinical deterioration leading to intubation or death. It was observational, and we cannot exclude the possibility of unmeasured confounders or hidden bias that account for the association between famotidine use and improved outcomes.
    keywords: covid-19; famotidine; patients; use
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        item: #6844 of 7819
          id: cord-343982-ymaql0hx
      author: Carr, M. J.
       title: Impact of COVID-19 on the diagnoses, HbA1c monitoring and mortality in people with type 2 diabetes: a UK-wide cohort study involving 13 million people in primary care
        date: 2020-10-27
       words: 4455
      flesch: 46
     summary: Using primary care data from 13 million people in the UK, and 10-year historical data, we have shown that within the first 4 months of the nationwide 'lockdown' in March 2020, the indirect consequences of the COVID-19 pandemic led to: i) a 69-70% reduction in new diagnoses of type 2 diabetes, with older individuals, males, and people from deprived areas experiencing the greatest reduction in diagnosis rates; ii) a 77-84% reduction in HbA1c testing; iii) a reduction in metformin and insulin prescribing, particularly in older people with type 2 diabetes, supporting the reduced rates of diagnosis and monitoring; and iv) a short-term 110% increase in mortality rate in people with type 2 diabetes in England and a 66% increased mortality rate across the rest of the UK. A study using primary care data from Salford, UK showed 135 fewer diagnoses of type 2 diabetes than expected between March and May 2020, which amounted to a 49% reduction in activity.
    keywords: data; diabetes; medrxiv; people; preprint; rates; type
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        item: #6845 of 7819
          id: cord-343985-0p2j5hzc
      author: Self-Brown, Shannon
       title: The Impact of COVID-19 on the Delivery of an Evidence-Based Child Maltreatment Prevention Program: Understanding the Perspectives of SafeCare® Providers
        date: 2020-11-05
       words: 7473
      flesch: 38
     summary: Providers who consented to the study were allowed to proceed to the main survey that included questions pertaining to how SafeCare delivery, the SafeCare workforce, and SafeCare families were being impacted by the COVID-19 pandemic. Reported rates of SafeCare virtual delivery were commensurate with what was reported in the larger field of evidence-based home visiting in the recent HARC survey report (O'Neill et al. 2020) .
    keywords: child; children; covid-19; delivery; families; home; maltreatment; pandemic; providers; safecare; survey
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        item: #6846 of 7819
          id: cord-344003-oul2hdyq
      author: Maleki Dana, Parisa
       title: An Insight into the Sex Differences in COVID-19 Patients: What are the Possible Causes?
        date: 2020-06-18
       words: 2766
      flesch: 42
     summary: 9 Evidence suggested that female patients experienced some COVID-19 symptoms significantly more than male patients, such as fatigue, anosmia, headache, sore throat, and nasal obstruction. Moreover, case fatalities are higher in male patients than female patients.
    keywords: ace2; covid-19; differences; men; patients; sars; sex; women
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        item: #6847 of 7819
          id: cord-344006-0iq9s94n
      author: Atzrodt, Cassandra L.
       title: A Guide to COVID‐19: a global pandemic caused by the novel coronavirus SARS‐CoV‐2
        date: 2020-05-23
       words: 7289
      flesch: 47
     summary: Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the Race to find COVID-19 treatments accelerates Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase Accepted Article RNA-Dependent RNA Polymerase by Remdesivir 120 Gilead Sciences Gilead Announces Results From Phase 3 Trial of Investigational Antiviral Remdesivir in Patients With Severe COVID-19 Some FDA Approved drugs exhibit binding affinity as high as kcal/mol against COVID-19 Main Protease (Mpro): A Molecular Docking Study IndiaRxiv Major ongoing clinical trials for COVID-19 treatment and studies currently being conducted or scheduled in Japan. CNN Kamisar B Oxford scientist says its vaccine is making headway, could show efficacy by WSJ News Exclusive | Drugmaker Moderna Delivers First Experimental Coronavirus Vaccine for Human Testing Long-term protection from SARS coronavirus infection conferred by a single immunization with an attenuated VSV-based vaccine Live bacterial vaccines -a review and identification of potential hazards.
    keywords: article; cell; copyright; coronavirus; cov-2; covid-19; disease; drugs; human; patients; rights; rna; sars; symptoms; testing; vaccine; virus
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        item: #6848 of 7819
          id: cord-344008-h4kc04w0
      author: Liang, Donghai
       title: Urban Air Pollution May Enhance COVID-19 Case-Fatality and Mortality Rates in the United States
        date: 2020-09-21
       words: 5756
      flesch: 37
     summary: Descriptive statistics was conducted on 3,122 US counties using data reported as of July 17, 2020 **COVID-19 case fatality rate was calculated by the number of deaths divided by the number of cases, reported as of July 17, 2020 An analysis of 213 cities in China recently demonstrated that temporal increases in COVID-19 cases were associated with short-term variations in ambient air pollution 18 .
    keywords: air; case; county; covid-19; fatality; level; mortality; pollution; rate
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        item: #6849 of 7819
          id: cord-344010-14bd6mnp
      author: Husby, A.
       title: Inhaled corticosteroid use in COVID-19
        date: 2020-09-03
       words: 3520
      flesch: 35
     summary: In sensitivity analyses, we looked into the effect of inhaled corticosteroid use by excluding individuals with oral corticosteroid use within the last six months (Table S5) , different periods of the COVID-19 epidemic (Table S6) , different influenza seasons (Table S7) , persistency of ICS use (Table S8) , and xanthines and leukotriene receptor antagonist use (Table S9) , and found no noticeable differences in the hazard of the combined endpoint in different subgroups. Having detailed information on ICS subtypes, persistency of ICS use, and per oral corticosteroid use, additionally allowed us to scrutinize the role of differential inhaled corticosteroids use.
    keywords: covid-19; ics; patients; use; users
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        item: #6850 of 7819
          id: cord-344011-w9zn7hb2
      author: Schiffrin, Ernesto L
       title: Response to COVID-19 and ACEI/ARB: NOT ASSOCIATED?
        date: 2020-05-16
       words: 672
      flesch: 35
     summary: A c c e p t e d M a n u s c r i p t 4 COVID-19 and ACEI/ARB: NOT ASSOCIATED? Hypertension and COVID-19 Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa Association of Renin-Angiotensin System Inhibitors With Severity or Risk of Death in Patients With Hypertension Hospitalized for Coronavirus Disease 2019 (COVID-19) Infection in Wuhan, China Drug Therapy, and Mortality in Covid-19 Renin-Angiotensin-Aldosterone System Blockers and the Risk of Covid-19 Association of Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Testing Positive for Coronavirus Disease HFSA/ACC/AHA Statement Addresses Concerns Re: Using RAAS Antagonists in COVID-19 ACE2 is in fact widely distributed, and was recently demonstrated in nasal epithelial goblet/secretory cells and in nasal epithelial ciliated cells, in corneal cells in the eye, and in esophagus and intestinal epithelial cells 4 as well as in oral mucosa cells, 5 which are probably ways whereby the virus enters the body and proliferates to eventually infect the lower respiratory tract and the lung.
    keywords: angiotensin; cells; covid-19
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        item: #6851 of 7819
          id: cord-344012-npob20n0
      author: Gheblawi, Mahmoud
       title: Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System: Celebrating the 20th Anniversary of the Discovery of ACE2
        date: 2020-05-08
       words: 10498
      flesch: 27
     summary: Ang II can regulate ACE2 expression through the AT 1 R. Healthy hearts and kidneys are characterized by high levels of ACE2 mRNA and protein expression, with moderate expression of ACE. Pharmacological RAS blockade agents, ARBs, in particular, are capable of modulating both systemic and tissue RAS, and simultaneously increasing ACE2 expression and activity in experimental models.
    keywords: ace2; ang ii; angiotensin; converting; coronavirus; cov-2; covid-19; disease; effects; enzyme; expression; gut; heart; hypertension; lung; mice; patients; ras; receptor; sars
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        item: #6852 of 7819
          id: cord-344027-qghktrm1
      author: Fiolet, Thibault
       title: 'Effect of hydroxychloroquine with or without azithromycin on the mortality of COVID-19 patients' – Author’s reply
        date: 2020-10-17
       words: 330
      flesch: 23
     summary: key: cord-344027-qghktrm1 authors: Fiolet, Thibault; Guihur, Anthony; Rebeaud, Mathieu E.; Mulot, Matthieu; Peiffer-Smadja, Nathan; Mahamat-Saleh, Yahya title: 'Effect of hydroxychloroquine with or without azithromycin on the mortality of COVID-19 patients' – Author’s reply date: 2020-10-17 journal: Clin Microbiol Infect DOI: 10.1016/j.cmi.2020.10.002 sha: doc_id: 344027 cord_uid: qghktrm1 nan 3) A critical analysis of chloroquine and hydroxychloroquine 178 clinical pharmacology Concentration-dependent mortality of chloroquine in overdose Utilization 184 of COVID-19 treatments and clinical outcomes among patients with cancer: A COVID-185 19 and Cancer Consortium (CCC19) cohort study Interventions 188 for treatment of COVID-19: A living systematic review with meta-analyses and trial 189 sequential analyses (The LIVING Project) Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19: an 193 international collaborative meta-analysis of randomized trials Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: 203 a randomized trial
    keywords: covid-19; hydroxychloroquine
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        item: #6853 of 7819
          id: cord-344046-9vou06c7
      author: Hon, Kam Lun Ellis
       title: Pediatric COVID-19: what disease is this?
        date: 2020-06-17
       words: 1069
      flesch: 34
     summary: World J Pediatr SARS-CoV-2 infection in children Epidemiology of COVID-19 among children in China Coronavirus in France: healthy 16 year-old dies of COVID-19 Teen football player Jaquan Anderson dead from coronavirus in New Orleans Clinical presentations and outcome of severe acute respiratory syndrome in children Human coronavirus alone or in co-infection with rhinovirus C is a risk factor for severe respiratory disease and admission to the pediatric intensive care unit: a one-year study in Southeast Brazil Infection in the Perinatal Period of the Editorial Committee of Chinese Journal of Contemporary Pediatrics Perinatal and neonatal management plan for prevention and control of 2019 novel coronavirus infection Clinical, virologic and immunologic profiles of a young infant with severe acute respiratory syndrome Inflammatory cytokine profile in children with severe acute respiratory syndrome COVID-19: consider cytokine storm syndromes and immunosuppression SARS-CoV-2-induced Kawasaki-like hyperinflammatory syndrome: a novel COVID phenotype in children typhoon, cyclone or hurricane in patients with COVID-19? It is still unclear why coronavirus disease is milder in the pediatric population, similar to other respiratory viral illnesses.
    keywords: children; coronavirus; covid-19; syndrome
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        item: #6854 of 7819
          id: cord-344048-lx9krl5v
      author: Domínguez-Salas, Sara
       title: Psycho-Emotional Approach to the Psychological Distress Related to the COVID-19 Pandemic in Spain: A Cross-Sectional Observational Study
        date: 2020-06-28
       words: 5387
      flesch: 36
     summary: Ebola contacts' perceptions in Senegal Knowledge and risk perceptions of the Ebola virus in the United States Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China Association of self-perceptions of aging, personal and family resources and loneliness with psychological distress during the lock-down period of COVID-19 Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: A web-based cross-sectional survey A Review of Coronavirus Disease-2019 (COVID-19) Prediction for the spread of COVID-19 in India and effectiveness of preventive measures Lockdown contained the spread of 2019 novel coronavirus disease in Huangshi city, China: Early epidemiological findings Effectiveness of the measures to flatten the epidemic curve of COVID-19. The psychological impact of quarantine and how to reduce it: Rapid review of the evidence Misinformation of COVID-19 on the Internet: Infodemiology Study Top Concerns of Tweeters During the COVID-19 Pandemic: Infoveillance Study Chinese Public's Attention to the COVID-19 Epidemic on Social Media: Observational Descriptive Study The Impact of COVID-19 Epidemic Declaration on Psychological Consequences: A Study on Active Weibo Users Assessment of Health Information About COVID-19 Prevention on the Internet: Infodemiological Study.
    keywords: covid-19; distress; health; information; knowledge; measures; pandemic; participants; population; study
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        item: #6855 of 7819
          id: cord-344065-87x5y9o6
      author: Wedig, Isaac J
       title: Infographic. Stay physically active during COVID-19 with exercise as medicine
        date: 2020-10-23
       words: 640
      flesch: 45
     summary: 6 Immediate action is required to facilitate physical activity during the COVID-19 pandemic because it is an effective form of medicine 3 to promote good health, prevent disease and bolster immune function. Several organisations including the WHO, American Heart Association and American College of Sports Medicine have offered initial suggestions and resources for engaging in physical activity during the COVID-19 pandemic.
    keywords: activity; covid-19
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        item: #6856 of 7819
          id: cord-344070-17oac3bg
      author: Silverman, Justin D
       title: Using ILI surveillance to estimate state-specific case detection rates and forecast SARS-CoV-2 spread in the United States
        date: 2020-04-03
       words: 5100
      flesch: 52
     summary: Many states, including Washington, New York, Oregon, Pennsylvania, Maryland, Colorado, New Jersey, and Louisiana, have had a recent surge in number of non-influenza ILI cases far in excess of seasonal norms. This assumption allows us to calculate the number of non-influenza ILI cases as The resulting time-seriesỹ it are shown in Figure S4 .
    keywords: cov-2; covid; ili; influenza; license; preprint; rate; sars
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        item: #6857 of 7819
          id: cord-344075-ucd6ooob
      author: Bartoszek, Adrian
       title: Mental Well-Being (Depression, Loneliness, Insomnia, Daily Life Fatigue) during COVID-19 Related Home-Confinement—A Study from Poland
        date: 2020-10-12
       words: 4520
      flesch: 46
     summary: Respondents who started taking any new drugs during COVID-19 home confinement had higher outcomes in all questionnaires. To extend the scope of the research on the topic, we decided to include some further factors that may be associated with varying mental health outcomes during COVID-19 home confinement.
    keywords: confinement; covid-19; depression; fatigue; health; home; insomnia; pandemic; study
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        item: #6858 of 7819
          id: cord-344076-ervwj8ok
      author: Lim, Michael Anthonius
       title: The insidious threat of jamu and unregulated traditional medicines in the COVID-19 era
        date: 2020-06-12
       words: 801
      flesch: 26
     summary: Such circumstances can cause complications and further exacerbate the outcomes of COVID-19 patients with underlying comorbidities Therefore, obtaining a comprehensive history, including consumption of jamu and other unregulated traditional medicines, is crucial for the early identification of steroid dependence.
    keywords: covid-19; jamu; patients
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        item: #6859 of 7819
          id: cord-344080-tru8kvxw
      author: Bhatt, Ankeet S.
       title: Declines in Hospitalizations for Acute Cardiovascular Conditions During the COVID-19 Pandemic: A Multicenter Tertiary Care Experience
        date: 2020-05-26
       words: 2411
      flesch: 31
     summary: Methods We tracked acute cardiovascular hospitalizations between January 1st, 2019 and March 31st, 2020. Conclusions During the first phase of the COVID-19 pandemic, there was a marked decline in acute cardiovascular hospitalizations and patients who were admitted had shorter lengths of stay.
    keywords: conditions; covid-19; hospitalizations; march; pandemic; patients
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        item: #6860 of 7819
          id: cord-344087-4f40zj13
      author: Jo, Min-Woo
       title: The Burden of Disease due to COVID-19 in Korea Using Disability-Adjusted Life Years
        date: 2020-05-26
       words: 3405
      flesch: 56
     summary: While it was initially reported that about 80% of confirmed COVID-19 cases are mild with an estimated case fatality of 2.3%, 1 the exceptional infection rates of COVID-19 have created multiple cases everywhere at the same time, resulting in increased burden of disease and increased case fatality which has now risen above 7.1%. Lastly, as early detections of cases also could reduce their reproductive number, it might reduce incidence of The DALY metric, as a summary measure of disease burden, is useful in identifying the impact of a disease on public health, especially the impact of infectious diseases in epidemic situations.
    keywords: burden; covid-19; dalys; disease; years
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        item: #6861 of 7819
          id: cord-344117-lr6roxej
      author: Vieira, Ana Luisa Silveira
       title: Role of point-of-care ultrasound during the COVID-19 pandemic: our recommendations in the management of dialytic patients
        date: 2020-06-03
       words: 4408
      flesch: 41
     summary: Moreover, dialysis patients are more vulnerable to infection due to suppression of the immune system. Reports from health services around the world have indicated that patients with diabetes mellitus and hypertension, two of the main causes of ESRD worldwide, and also advanced age and cardiovascular complications, two frequent accompanying conditions in dialysis patients, are more susceptible to SARS-CoV-2 infection and more prone to develop severe COVID-19 pneumonia, eventually requiring intensive care treatment
    keywords: covid-19; disease; lines; lung; lus; patients; pneumonia; ultrasound
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        item: #6862 of 7819
          id: cord-344120-7t5ce2hb
      author: Baroutjian, Amanda
       title: SARS-CoV-2 pharmacologic therapies and their safety/effectiveness according to level of evidence
        date: 2020-09-01
       words: 5292
      flesch: 49
     summary: While we await higher quality evidence from randomized control trials and meta-analyses, these results provide some context on the efficacy of pharmacologic therapy in COVID-19 patients. In the absence of a vaccine available to the public, there is a great need for level 1 evidence from randomized controlled trials and meta-analyses to support the development of evidence-based guidelines to treat COVID-19 patients.
    keywords: clinical; covid-19; day; days; group; improvement; patients; time
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        item: #6863 of 7819
          id: cord-344135-pyibu6rj
      author: Zuo, Peiyuan
       title: Decreased prealbumin level is associated with increased risk of mortality in hospitalized elderly patients with COVID-19
        date: 2020-07-03
       words: 3735
      flesch: 38
     summary: AST = aspartate transaminase; Hs-cTnI, High-sensitive cardiac troponin I. Obesity and impaired metabolic health in patients with COVID-19 Special considerations for nutritional studies in elderly Low prealbumin concentration was associated with increased risk of worse outcomes (all-cause death, ICU admission and mechanical ventilation) in elderly COVID-19 patients The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2 Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Clinical characteristics and outcomes of older patients with coronavirus disease 2019 (COVID-19) in Wuhan, China (2019): a single-centered, retrospective study Coronavirus disease 2019 in elderly patients: Characteristics and prognostic factors based on 4-week follow-up Transthyretin as a marker to predict outcome in critically ill patients Prealbumin improves death risk prediction of BNP-added Seattle Heart Failure Model: results from a pilot study in elderly chronic heart failure patients Serum prealbumin and its changes over time are associated with mortality in acute kidney injury Clinical characteristics of 80 hospitalized frontline medical workers infected with COVID-19 in Wuhan Clinical and CT features of early-stage patients with COVID-19: a retrospective analysis of imported cases in Shanghai, China Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease Prealbumin in nutrition evaluation Serum prealbumin: an independent marker of short-term energy intake in the presence of multiple-organ disease involvement The acute phase protein response in patients receiving subcutaneous IL-6 CRP/prealbumin, a novel inflammatory index for predicting recurrence after radical resection in gastric cancer patients: post hoc analysis of a randomized phase III trial Malnutrition in acute care patients: a narrative review Back to the Future: Lessons Learned From the 1918 SARS-CoV-2 and Zuo Peiyuan: Conceptualization, Methodology, Writing -Original Draft Each of the authors confirms that this manuscript has not been previously published and is not currently under consideration by any other journal. Univariate and multivariate logistic regression models were employed to evaluate the correlation between prealbumin and in-hospital outcomes (in-hospital mortality, ICU admission and mechanical ventilation) in elderly COVID-19 patients.
    keywords: admission; covid-19; disease; patients; prealbumin; risk; study
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        item: #6864 of 7819
          id: cord-344136-k5gh0s6y
      author: Ouyang, Lichen
       title: Association of acute kidney injury with the severity and mortality of SARS-CoV-2 infection: A meta-analysis
        date: 2020-09-02
       words: 2419
      flesch: 42
     summary: Most patients with COVID-19 are considered as non-severe patients and recover from this infection. We compared the laboratory indicators of renal impairment and incidences of AKI in the severe versus non-severe cases, and survival versus non-survival cases, respectively.
    keywords: aki; cases; clinical; covid-19; non; patients
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        item: #6865 of 7819
          id: cord-344162-8gbe6qo7
      author: Loomba, S.
       title: Measuring the Impact of Exposure to COVID-19 Vaccine Misinformation on Vaccine Intent in the UK and US
        date: 2020-10-26
       words: 8786
      flesch: 43
     summary: A final set of five pieces of misinformation comprising non-overlapping messaging and themes were selected to represent the diverse messaging found in COVID-19 vaccine misinformation (such as information questioning the importance or safety of a vaccine, see Figure 1 ). This analysis provides a platform to help us test and understand how more effective public health communication strategies can be designed and on whom these strategies would have the most positive impact in countering COVID-19 vaccine misinformation.
    keywords: covid-19; exposure; intent; media; medrxiv; misinformation; perpetuity; preprint; respondents; review; vaccination; vaccine
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        item: #6866 of 7819
          id: cord-344175-e2m9o8c2
      author: Lentini, Giovanni
       title: COVID-19, Chloroquine Repurposing, and Cardiac Safety Concern: Chirality Might Help
        date: 2020-04-16
       words: 2146
      flesch: 37
     summary: The desperate need to find drugs for COVID-19 has brought the attention of numerous scholars to the repurposing of known drugs as tentative COVID-19 therapeutics. It is logical that repurposing known drugs for COVID-19 may be first considered from pharmacological agents with proven efficacy against other highly pathogenic viral infections.
    keywords: activity; cardiac; chloroquine; drugs; enantiomers
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        item: #6867 of 7819
          id: cord-344185-jz6ui4w3
      author: Aziz, Aleha
       title: Building an Obstetric Intensive Care Unit during the COVID-19 Pandemic at a Tertiary Hospital and Selected Maternal-Fetal and Delivery Considerations
        date: 2020-07-24
       words: 4150
      flesch: 29
     summary: Responding rapidly to early warning signs of respiratory decompensation or worsening disease, following treatment protocols and best practices, working with interdisciplinary subspecialists, encouraging collaboration between physicians and nursing, and evaluating shortcomings in the system, were important elements in developing an effectively functioning OBICU that prioritized patient care and was optimized to provide the best possible outcomes for patients. As the subspecialist experts in critical care of obstetric patients, the MFM specialists and obstetric anesthesia physicians co-led the provision of critical care due to their understanding of physiological changes in pregnancy affecting health status, awareness regarding processes with potential for in-utero compromise, and alertness of complications endangering fetal well-being.
    keywords: care; covid-19; critical; delivery; labor; management; obicu; patients; physician; team; unit
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        item: #6868 of 7819
          id: cord-344198-jaagi88b
      author: Eimer, J.
       title: Tocilizumab shortens time on mechanical ventilation and length of hospital stay in patients with severe COVID‐19: a retrospective cohort study
        date: 2020-08-18
       words: 1521
      flesch: 37
     summary: Italy Abnormal pulmonary function in COVID-19 patients at time of hospital discharge Imbalanced host response to SARS-CoV-2 drives development of COVID-19 Impact of low dose tocilizumab on mortality rate in patients with COVID-19 related pneumonia Effective treatment of severe COVID-19 patients with tocilizumab Long-term complications of critical care Costs of providing infusion therapy for rheumatoid arthritis in a hospital-based infusion center setting We would like to express our gratitude towards all medical professional staff at Karolinska University Hospital for providing excellent care to patients with and without COVID-19 during the study period. key: cord-344198-jaagi88b authors: Eimer, J.; Vesterbacka, J.; Svensson, A.‐K.; Stojanovic, B.; Wagrell, C.; Sönnerborg, A.; Nowak, P. title: Tocilizumab shortens time on mechanical ventilation and length of hospital stay in patients with severe COVID‐19: a retrospective cohort study date: 2020-08-18 journal: J Intern Med DOI: 10.1111/joim.13162 sha: doc_id: 344198 cord_uid: jaagi88b among patients with COVID-19 who require treatment in intensive care for acute respiratory distress syndrome (ARDS), mortality rates have been reported between 16 - 78% (1).
    keywords: covid-19; patients; tocilizumab
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        item: #6869 of 7819
          id: cord-344204-qq2vqzc2
      author: Hariharan, Apurva
       title: The Role and Therapeutic Potential of NF-kappa-B Pathway in Severe COVID-19 Patients
        date: 2020-11-07
       words: 5660
      flesch: 33
     summary: The data from epidemiological studies revealed sex-specific differences in the incidence and mortality in COVID-19 patients, where the mortality rate of men is more than female. The possible reason for this cytokine storm in COVID-19 patients might be the elevated level of anti-viral inflammatory cytokines (IL-10, IL-6, IL-2, IFN-γ and TNF-α) which were attenuated and diversified in SARS and MERS infections, respectively .
    keywords: activation; coronavirus; covid-19; cytokine; et al; pathway; patients; sars; storm; tnf
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        item: #6870 of 7819
          id: cord-344213-j3yextjl
      author: Sze, Shirley
       title: The need for improved discharge criteria for hospitalised patients with COVID-19—implications for patients in long term care facilities
        date: 2020-09-19
       words: 1198
      flesch: 40
     summary: [1] Globally, a high proportion of long term care facilities (LTCF) have reported COVID-19 outbreaks, with high rates of morbidity and mortality in residents. Surveillance of COVID-19 at long-term care facilities in the EU/EEA Mortality associated with COVID-19 outbreaks in care homes : early international evidence.
    keywords: covid-19; discharge; patients; symptom
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        item: #6871 of 7819
          id: cord-344217-kci4uw7u
      author: Majid, Sabhiya
       title: Managing the COVID-19 Pandemic: Research Strategies Based on the Evolutionary and Molecular Characteristics of Coronaviruses
        date: 2020-08-25
       words: 5657
      flesch: 39
     summary: mSphere Multibasic cleavage site in the spike protein of SARS-CoV-2 is essential for infection of human lung cells Structure of SARS coronavirus spike receptor binding domain complexed with the receptor Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4 The bittersweet promise of glycobiology The novel coronavirus2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus Human coronavirus NL63employs the severe acute respiratory syndrome coronavirus receptor for cellular entry ACE2 of the heart: from angiotensin I to angiotensin (1-7) Identification of a coronavirus hemagglutinin-esterase with a substrate specificity different from those of influenza C virus and bovine coronavirus COVID-19 infection: origin, transmission, and characteristics of human coronaviruses Genome composition and divergence of the novel coronavirus (2019-nCoV) originating in China The Association of Cardiovascular Diseases and Diabetes Mellitus with COVID-19 (SARS-CoV-2) and their possible mechanisms Crystal structure of NL63 respiratory coronavirus receptor-binding complexed with its human receptor Structural basis of receptor recognition by SARS-CoV-2 Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26 Crystal structure of SARS-CoV-2 spike receptor-binding domain bound with ACE Clinical management of adult coronavirus infection disease 2019 (COVID-19) positive in the setting of low and medium intensity of care: a short practical review Master regulator analysis of the SARS-CoV-2 /human interactome COVID-19 outbreak: an update on therapeutic options Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations SN Compr Clin Med Cryo-electron tomography of mouse hepatitis virus: insights into the structure of the coronavirion The molecular biology of coronaviruses Coronavirus: organization, replication and expression of genome Mechanisms and enzymes involved in SARS coronavirus genome expression Pre-fusion structure of a human coronavirus spike protein The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles
    keywords: coronavirus; cov-2; covid-19; covs; disease; health; host; human; infection; novel; patients; protein; receptor; sars; syndrome
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        item: #6872 of 7819
          id: cord-344246-sf9cymhc
      author: Diriba, Kuma
       title: The effect of coronavirus infection (SARS-CoV-2, MERS-CoV, and SARS-CoV) during pregnancy and the possibility of vertical maternal–fetal transmission: a systematic review and meta-analysis
        date: 2020-09-04
       words: 5149
      flesch: 41
     summary: Only published articles with fully accessible data on pregnant women infected with SARS-CoV, MARS-CoV, and SARS-CoV-2 were included. From the total coronavirus infected pregnant women, 56.9% delivered by cesarean, 31.3% admitted to ICU, while 2.7% were died.
    keywords: coronavirus; cov; covid-19; infection; maternal; pregnancy; sars; studies; transmission; women
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        item: #6873 of 7819
          id: cord-344252-6g3zzj0o
      author: Farooq, Junaid
       title: A Novel Adaptive Deep Learning Model of Covid-19 with focus on mortality reduction strategies
        date: 2020-07-21
       words: 6952
      flesch: 51
     summary: Deep learning and other machine learning techniques stand out in solving problems of data based model parameter estimation due to their state-of-the-art results. Different models have been developed to analyse the transmission dynamics of many infectious diseases like malaria (Ronald Ross model)
    keywords: data; deaths; disease; group; learning; model; number; population; risk; time
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        item: #6874 of 7819
          id: cord-344262-5yk1keg3
      author: Evans, Lauran K.
       title: COVID-19 Drive-Through Point of Screening and Testing (POST) System: A Safe, Efficient, and Adaptable Model for Nasopharyngeal Swab Collection
        date: 2020-09-02
       words: 4343
      flesch: 52
     summary: The authors also believe that the WCHD POST system, similar to those previously reported in the literature, represents a particularly efficient, safe, and adaptable model for COVID-19 testing, and recommend that other COVID-19 testing sites nationwide consider adopting it for their own purposes. This POST drive-through system serves as an efficient, safe, and adaptable model for high volume COVID-19 nasopharyngeal swabbing that the authors recommend other COVID-19 testing sites nationwide consider adopting for their own use.
    keywords: covid-19; drive; patients; post; ppe; site; system; testing; time
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        item: #6875 of 7819
          id: cord-344264-7fkaj1h8
      author: Ding, Jinli
       title: Experience on radiological examinations and infection prevention for COVID-19 in radiology department
        date: 2020-03-31
       words: 1807
      flesch: 42
     summary: Within one month, the novel coronavirus rapidly spread across the whole of China through droplet transmission and contact transmission, and the reported number of confirmed COVID-19 cases demonstrated a rising trend. For severe patients in isolation yard, clinical photography is suggested.
    keywords: china; coronavirus; covid-19; novel; patients
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        item: #6876 of 7819
          id: cord-344270-874i31h8
      author: Radke, Robert M
       title: Adult congenital heart disease and the COVID-19 pandemic
        date: 2020-06-10
       words: 4678
      flesch: 35
     summary: For example, patients with severely reduced systolic ventricular function would be considered high-risk individuals irrespective of underlying heart defect, whereas some patients with more complex lesions such as repaired tetralogy of Fallot or transposition of the great arteries after arterial switch operation with pristine haemodynamics are classified as lower risk patients. Based on the anatomy of the underlying cardiac lesion and additional physiological considerations such as symptoms, Review box 1 summary of specific considerations for severely affected AChD patients Key issues for critical care management of COVID-19 patients with congenital heart disease general considerations ► Admit to secondary or tertiary adults with congenital heart disease (ACHD) centre.
    keywords: achd; ards; care; covid-19; disease; heart; patients; right; risk; sars
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        item: #6877 of 7819
          id: cord-344284-dn9nlcgs
      author: Xia, Wei
       title: Clinical and CT features in pediatric patients with COVID‐19 infection: Different points from adults
        date: 2020-03-05
       words: 1470
      flesch: 48
     summary: As the clinical and imaging features of pediatric patients with COVID-19 infection were limited, we would like to present a series of 20 cases who have been identified by the pharyngeal swab COVID-19 nucleic acid test. Radiology Emerging coronavirus 2019-nCoV pneumonia Differentiation of bacterial and viral pneumonia in children Clinical and CT features in pediatric patients with COVID-19 infection: Different points from adults The authors declare that there are no conflict of interests.
    keywords: cases; covid-19; infection; patients
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        item: #6878 of 7819
          id: cord-344291-i5wqlzif
      author: Estalella, Gemma Martinez
       title: GESTIÓN Y LIDERAZGO DE LOS SERVICIOS DE ENFERMERÍA EN EL PLAN DE EMERGENCIA DE LA PANDEMIA COVID-19: LA EXPERIENCIA DEL HOSPITAL CLÍNIC DE BARCELONA
        date: 2020-05-15
       words: 4547
      flesch: 32
     summary: No existe precedente ni publicaciones relacionadas con la gestión y liderazgo de los servicios de enfermería en España dentro del plan de emergencia de la pandemia COVID-19. La organización actual de la dirección enfermera es una estructura que pone en valor la transversalidad entre los diferentes institutos, áreas y centros del hospital que permite disponer de una visión integral de la organización y dar respuesta a las necesidades de los diferentes profesionales y de la sociedad en general.
    keywords: asistenciales; barcelona; como; con; covid-19; crisis; cuidados; de la; de los; del; dirección; enfermería; esta; gestión; hospital; las; los; pacientes; pandemia; para; personal; por; profesionales; que; salud; semana; servicios; sus; todos; una
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        item: #6879 of 7819
          id: cord-344295-gwbmsmbv
      author: Jenei, Kristina
       title: Challenges and opportunities for graduate students in public health during the COVID-19 pandemic
        date: 2020-06-04
       words: 1000
      flesch: 42
     summary: Furthermore, it necessitates unpaid work and program derailment, which is impossible for many students during an economic downturn. However, it also offers many novel opportunities for public health students to learn and contribute.
    keywords: covid-19; health; students
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        item: #6880 of 7819
          id: cord-344302-p0v6sl9x
      author: Gubitosa, James C
       title: COVID-19-Associated Acute Limb Ischemia in a Patient on Therapeutic Anticoagulation
        date: 2020-09-25
       words: 3104
      flesch: 36
     summary: Role of endothelial inflammation Arterial thromboembolic complications in COVID-19 in low-risk patients despite prophylaxis Endothelial cell infection and endotheliitis in COVID-19 Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases Prominent changes in blood coagulation of patients with SARS-CoV-2 infection Hypercoagulability of COVID-19 patients in intensive care unit. A case series by Gonzalez et al. described three cases of peripheral arterial thrombosis in COVID-19 patients [7] .
    keywords: anticoagulation; covid-19; patient; reference; thrombosis
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        item: #6881 of 7819
          id: cord-344308-ijrze203
      author: Bezzerri, Valentino
       title: Does cystic fibrosis constitute an advantage in COVID-19 infection?
        date: 2020-10-06
       words: 1150
      flesch: 42
     summary: Increased neutrophil extracellular traps (NET) have been hypothesized to be predictive of poor outcome in COVID-19 patients [3] . Surprisingly, we found that CF patients were significantly protected against infection by SARS-CoV-2.
    keywords: covid-19; data; patients
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        item: #6882 of 7819
          id: cord-344326-025ioy3r
      author: Usman, AA
       title: A Case Series of Devastating Intracranial Hemorrhage during Venovenous Extracorporeal Membrane Oxygenation for COVID-19
        date: 2020-07-28
       words: 2996
      flesch: 38
     summary: Although we temporarily ceased using heparin infusions in COVID-19 ECMO patients, we have not yet experienced an increase in fatal thrombotic complications or reduced circuit durability. 3, 16, 17 The neurological outcomes for ECMO patients in these studies were not reported.
    keywords: anticoagulation; covid-19; ecmo; extracorporeal; hemorrhage; patients; stroke
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        item: #6883 of 7819
          id: cord-344357-ocyaqs1y
      author: Fu, Yue-Qiang
       title: Effect of blood analysis and immune function on the prognosis of patients with COVID-19
        date: 2020-10-30
       words: 4485
      flesch: 54
     summary: Another study also indicated that COVID-19 patients in the death group had significantly lower lymphocyte count on admission than the recovered group [8] . In the present study, the ROC analysis determined that admission leukocyte count, neutrophil percentage, neutrophil count, lymphocyte percentage, and lymphocyte count were able to predict the mortality of COVID-19 patients.
    keywords: cd4; count; covid-19; group; lymphocyte; neutrophil; patients
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        item: #6884 of 7819
          id: cord-344361-amhc0ryh
      author: Ruggiero, Giuseppe
       title: Reply to: “Characterization of acute acro-ischemic lesions in non-hospitalized patients: a case series of 132 patients during the COVID-19 outbreak”
        date: 2020-06-01
       words: 578
      flesch: 51
     summary: key: cord-344361-amhc0ryh authors: Ruggiero, Giuseppe; Arcangeli, Fabio; Lotti, Torello; Ametrano, Orsola; Ruggiero, Cosimo; Cucchiara, Salvatore; Oliva, Salvatore title: Reply to: “Characterization of acute acro-ischemic lesions in non-hospitalized patients: a case series of 132 patients during the COVID-19 outbreak” date: 2020-06-01 journal: J Am Acad Dermatol DOI: 10.1016/j.jaad.2020.05.122 sha: doc_id: 344361 cord_uid: amhc0ryh nan We read with interest Characterization of acute acro-ischemic lesions in non-hospitalized patients: a case series of 132 patients during the COVID-19 outbreak [1] . Pediatric Gastroenterology and Liver Unit, Maternal and Child Health Department Characterization of acute acro-ischemic lesions in non-hospitalized patients: a case series of 132 patients during the COVID-19 outbreak Epidemiological characteristics of 2143pediatric patients with 2019 coronavirus disease in China Delayed access or provision of care in Italy resulting from fear of COVID-19
    keywords: covid-19; patients
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        item: #6885 of 7819
          id: cord-344375-pr6jlc5c
      author: Emert, Roger
       title: COVID-19 and hypercoagulability in the outpatient setting
        date: 2020-05-23
       words: 902
      flesch: 27
     summary: A Report of Thromboelastography Findings and other Parameters of Hemostasis Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19 Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak Mild or Moderate Covid-19 Pulmonary embolism in patients with Covid-19 pneumonia Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Hypercoagulability of COVID-19 patients in Intensive Care Unit.
    keywords: covid-19; patients; vte
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        item: #6886 of 7819
          id: cord-344382-vge4ho2v
      author: De Flora, Silvio
       title: Rationale for the use of N‐acetylcysteine in both prevention and adjuvant therapy of COVID‐19
        date: 2020-08-11
       words: 5006
      flesch: 32
     summary: 34 A prospective, randomized, controlled trial in the Shandong Province, China enrolling adult bronchiectasis patients with at least two exacerbations in the previous year showed that oral NAC (600 mg twice daily for 12 months) was able to reduce the risk of exacerbations. Persons who have been in proximity of infected SARS-CoV-2 carriers, including those detected by means of smartphone contact tracing apps, may be an additional target for taking oral NAC in order to decrease the risk of developing COVID-19.
    keywords: acetylcysteine; cells; covid-19; disease; glutathione; gsh; influenza; nac; patients; role; sars; stress; virus
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        item: #6887 of 7819
          id: cord-344389-aj9q73f0
      author: Brosnahan, Shari B.
       title: COVID-19 Pneumonia Hospitalizations Followed by Re-presentation for Presumed Thrombotic Event
        date: 2020-06-23
       words: 1670
      flesch: 35
     summary: These observations have raised our concern regarding a continued hypercoagulable state in COVID-19 patients despite clinical stability that exists post-hospitalization; patients with certain risk factors may benefit from extended VTE prophylaxis. 15 While classic disseminated intravascular coagulation (DIC) has also been identified in certain COVID-19 patients, the incidence of this is seemingly rare.
    keywords: covid-19; discharge; patients; prophylaxis; thrombosis
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        item: #6888 of 7819
          id: cord-344400-2gzip67i
      author: Zimmermann, M.
       title: They stumble that run fast: the economic and COVID-19 transmission impacts of reopening industries in the US
        date: 2020-06-12
       words: 3101
      flesch: 52
     summary: key: cord-344400-2gzip67i authors: Zimmermann, M.; Benefield, A. E.; Althouse, B. M. title: They stumble that run fast: the economic and COVID-19 transmission impacts of reopening industries in the US date: 2020-06-12 journal: nan DOI: 10.1101/2020.06.11.20128918 sha: doc_id: 344400 cord_uid: 2gzip67i COVID-19 has laid bare the United States economically and epidemiologically. Ideally, leaders will target reopening industries that have experienced large unemployment or overall economic distress due to COVID-19, however, it is also important to consider the transmission risks in each industry.
    keywords: industry; preprint; reopening; risk; states; transmission
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        item: #6889 of 7819
          id: cord-344404-whdxjef0
      author: Fatmi, Mahmudur Rahman
       title: COVID – 19 Impact on Urban Mobility
        date: 2020-08-14
       words: 2430
      flesch: 51
     summary: The survey collected data related to the daily activities, long distance travel, and sociodemographic information from respondents around the world. Long distance travel is analyzed by travel mode and individuals' occupation (Fig. 5) .
    keywords: activities; covid; home; travel
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        item: #6890 of 7819
          id: cord-344425-27q9x6hb
      author: Mantica, Guglielmo
       title: Reply to D.G. Barten et al “Re: Non-COVID-19 visits to emergency departments during the pandemic: the impact of fear”
        date: 2020-07-13
       words: 431
      flesch: 42
     summary: In this perspective, streamline the workflow in Emergency Departments and non-COVID Departments as well as effective communication by the health-care system of different countries becomes fundamental in order to provide patients with COVID-free pathways, thus reducing delay in diagnosis and treatment. and we do strongly agree with the Authors about some indirect effects of the lockdown during the COVID-19 pandemic, such as social distancing, reduction of working hours, and traffic movements as co-responsible for the reduced access to the emergency departments by non-COVID-19 patients.
    keywords: covid-19
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        item: #6891 of 7819
          id: cord-344445-slv7r9u7
      author: Vakharia, Kunal
       title: The right to know: ethical implications of antibody testing for healthcare workers and overlooked societal implications
        date: 2020-06-03
       words: 2416
      flesch: 45
     summary: The promise and peril of antibody testing for COVID-19 Antibody testing for Covid-19 The potential danger of suboptimal antibody responses in COVID-19 Emergence of drift variants that may affect COVID-19 vaccine development and antibody treatment HIV antibody screening in a general Hospital population The Richest neighborhoods Emptied out most as coronavirus hit New York City Show me your Passport: ethical concerns about Covid-19 antibody testing as key to reopening public life Mandatory screening for HIV antibody HIV antibody screening. With limited knowledge about the significance of COVID-19 antibody testing at this time, it is hard to use this to stratify work in a healthcare setting or to use it for any purpose beyond epidemiological studies on the spread of the disease.
    keywords: antibody; covid-19; immunity; potential; testing
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        item: #6892 of 7819
          id: cord-344486-iu5flbcl
      author: Chiotos, Kathleen
       title: Multicenter interim guidance on use of antivirals for children with COVID-19/SARS-CoV-2
        date: 2020-09-12
       words: 8619
      flesch: 24
     summary: Antiviral Activity and Safety of Darunavir/Cobicistat for the Treatment of COVID-19 Comparison of hydroxychloroquine, lopinavir/ritonavir, and standard of care in critically ill patients with SARS-CoV-2 pneumonia: an opportunistic retrospective analysis Stopping lopinavir/ritonavir in COVID-19 patients: duration of the drug interacting effect Clinical Characteristics and Disease Progression in Early-Stage COVID-19 Patients in South Korea Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study Guidance statement: Remdesivir is suggested for children with severe COVID-19.
    keywords: children; coronavirus; covid-19; data; days; disease; hydroxychloroquine; patients; pediatric; remdesivir; risk; sars; study; treatment; trial; use
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        item: #6893 of 7819
          id: cord-344498-mwgccbfo
      author: Casado-Aranda, Luis-Alberto
       title: Analysis of the Scientific Production of the Effect of COVID-19 on the Environment: A Bibliometric Study
        date: 2020-11-03
       words: 5784
      flesch: 34
     summary: This study is not only a first in the evolution of COVID-19 research from the specific perspective of environmental studies, but will be of extreme utility for information professionals to disseminate objective and quality coverage on the effects of the virus on the environment. Thus the co-word analysis applied text-mining techniques to the titles, abstracts, and keywords leading to the design, based on fundamental bibliometric indicators such as the number of publications, of a strategic diagram illustrating the main themes of interest related to the issue of environment in COVID-19 research.
    keywords: air; analysis; covid-19; effects; environmental; et al; information; pandemic; quality; research; science; smart; studies; study
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        item: #6894 of 7819
          id: cord-344501-kc0q6k6j
      author: Zhu, Yongjian
       title: The mediating effect of air quality on the association between human mobility and COVID-19 infection in China
        date: 2020-07-09
       words: 3004
      flesch: 43
     summary: We applied the generalized additive model to examine the association of human mobility index with COVID-19 confirmed cases, and to assess the mediating effects of air quality index and each pollutant. We observed a significant positive relationship between human mobility index and the daily counts of COVID-19 confirmed cases.
    keywords: air; covid-19; human; mobility; quality
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        item: #6895 of 7819
          id: cord-344503-gw5d721n
      author: Yousefzadegan, Sedigheh
       title: Case Report: Death due to COVID-19 in Three Brothers
        date: 2020-04-10
       words: 958
      flesch: 55
     summary: Considering the fact that most of them who are affected by COVID-19 recover, deaths in three brothers who lived separately and had no known underlying disease suggest genetic predisposition to COVID-19 in some individuals. Considering the fact that most of them who are affected by COVID-19 recover, deaths in three brothers who lived separately and had no known underlying disease suggest genetic predisposition to COVID-19 in some individuals.
    keywords: brothers; covid-19
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        item: #6896 of 7819
          id: cord-344508-a67vsux2
      author: Campanile, Fabio Cesare
       title: Acute cholecystitis during COVID-19 pandemic: a multisocietary position statement
        date: 2020-06-08
       words: 2397
      flesch: 36
     summary: Langenbeck's Arch Surg Laparoscopic approach to acute abdomen from the Consensus Development Conference of the Società Italiana di Chirurgia Endoscopica e nuove tecnologie (SICE) WSES and SICG guidelines on acute calcolous cholecystitis in elderly population Surgical smoke and infection control Detecting hepatitis B virus in surgical smoke emitted during laparoscopic surgery SARS-C oV-2 is present in peritoneal fluid in COVID-19 patients. E-published ahead-of-print A low cost, safe and effective method for smoke evacuation in laparoscopic surgery for suspected coronavirus patients Systematic review of cholecystostomy as a treatment option in acute cholecystitis Cholecystectomy in elderly: challenge and critical analysis of available evidence Outcome comparison between percutaneous cholecystostomy and cholecystectomy: a 10-year population-based analysis Emergent cholecystectomy is superior to percutaneous cholecystostomy tube placement in critically ill patients with emergent calculous cholecystitis Laparoscopic cholecystectomy versus percutaneous catheter drainage for acute cholecystitis in high risk patients (CHOCOLATE): multicentre randomised clinical trial Early percutaneous cholecystostomy in severe acute cholecystitis reduces the complication rate and duration of hospital stay Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations All the authors contributed equally to this article.
    keywords: acute; cholecystectomy; cholecystitis; covid-19; patients; surgery
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        item: #6897 of 7819
          id: cord-344529-k6divntz
      author: Mburu, C. N.
       title: The importance of supplementary immunisation activities to prevent measles outbreaks during the COVID-19 pandemic in Kenya
        date: 2020-08-31
       words: 5417
      flesch: 48
     summary: For projections, we assumed these results reflected measles immunity in Kilifi in August 2019, and assumed 96% of persons >15 years had protective measles antibodies concentrations, similar to findings in adults in Nairobi in 2007-2009 13 (Table 1) . We adapted a static cohort model of measles immunity 17 to estimate age stratified population immunity profile in Kilifi by combining recent measles serological data with new vaccine-derived immunity during the prediction period using the local vaccination schedule, MCV1 and MCV2 uptake, and vaccine efficacy.
    keywords: coverage; immunity; measles; medrxiv; outbreak; preprint; risk; vaccination
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        item: #6898 of 7819
          id: cord-344553-uya1j94u
      author: Bodova, K.
       title: Time-adjusted Analysis Shows Weak Associations Between BCG Vaccination Policy and COVID-19 Disease Progression
        date: 2020-05-06
       words: 3864
      flesch: 41
     summary: No evidence from a regression discontinuity analysis Exercising caution in correlating COVID-19 incidence and mortality rates with BCG vaccination policies due to variable rates of SARS CoV-2 testing Johns Hopkins University Novel Coronavirus (COVID-19) Cases Data Application of BCG vaccine for immune-prophylaxis among Egyptian healthcare workers during the pandemic of COVID-19 Patterns of the COVID19 epidemic spread around the world: exponential vs power laws Incubation period and other epidemiological characteristics of 2019 novel coronavirus infections with right truncation: a statistical analysis of publicly available case data Differences in power-law growth over time and indicators of COVID-19 pandemic progression worldwide Correlation between universal BCG vaccination policy and reduced morbidity and mortality for COVID-19: an epidemiological study Non-specific effects of BCG vaccine on viral infections Early epidemiological assessment of the virulence of emerging infectious diseases: a case study of an influenza pandemic CSV mit den aktuellen Covid-19 Infektionen pro Tag (Zeitreihe) Using a delay-adjusted case fatality ratio to estimate under-reporting. key: cord-344553-uya1j94u authors: Bodova, K.; Boza, V.; Brejova, B.; Kollar, R.; Mikusova, K.; Vinar, T. title: Time-adjusted Analysis Shows Weak Associations Between BCG Vaccination Policy and COVID-19 Disease Progression date: 2020-05-06 journal: nan DOI: 10.1101/2020.05.01.20087809 sha: doc_id: 344553 cord_uid: uya1j94u In this study, we ascertain the associations between BCG vaccination policies and progression of COVID-19 through analysis of various time-adjusted indicators either directly extracted from the incidence and death reports, or estimated as parameters of disease progression models.
    keywords: bcg; cases; countries; covid-19; number; policies; time; vaccination
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        item: #6899 of 7819
          id: cord-344566-r75o7ips
      author: Temiz, Selami Aykut
       title: Evaluation Of Dermatology Consultations In The Era Of COVID19
        date: 2020-05-22
       words: 1928
      flesch: 41
     summary: Dermatology consultation cases in the era of COVID-19 pandemic between 11 March 2020 and 4 May 2020 were retrospectively evaluated. Similar to pre-pandemic dermatology consultations, the ratio of males and females were found to be nearly the same in our study (8, 9, 10, 11) .
    keywords: consultations; dermatology; pandemic; patients
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        item: #6900 of 7819
          id: cord-344572-90gqyn1q
      author: Lee, Whanhee
       title: COVID-19 in South Korea: epidemiological and spatiotemporal patterns of the spread and the role of aggressive diagnostic tests in the early phase
        date: 2020-08-04
       words: 4448
      flesch: 50
     summary: The definition of COVID-19 cases in Korea is displayed in Table 1 . We collected daily data on the number of confirmed cases, tests and deaths due to COVID-19 from 20 January to 13 April 2020.
    keywords: areas; cases; covid-19; epidemic; korea; number; spread; testing
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        item: #6901 of 7819
          id: cord-344581-h7ikjgic
      author: Ong, David S.Y.
       title: Comparison of diagnostic accuracies of rapid serological tests and ELISA to molecular diagnostics in patients with suspected COVID-19 presenting to the hospital
        date: 2020-06-02
       words: 2076
      flesch: 47
     summary: Clinical Characteristics of Coronavirus Disease 2019 in China Rapidly increasing cumulative incidence of coronavirus disease (COVID-19) in the European Union/European Economic Area and the United Kingdom Current information about the novel coronavirus (COVID-19) Bilthoven: RIVM Better tests, better care: improved diagnostics for infectious diseases SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Performance of VivaDiag COVID-19 IgM/IgG Rapid Test is inadequate for diagnosis of COVID-19 in acute patients referring to emergency room department Evaluation of a COVID-19 IgM and IgG rapid test; an efficient tool for assessment of past exposure to SARS-CoV-2 Development and clinical application of a rapid IgM-IgG combined antibody test for SARS-CoV-2 infection diagnosis Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease Antibody Detection and Dynamic Characteristics in Patients with COVID-19 Boson Biotech Rapid 2019-nCoV IgG/IgM Combo Test Card 10 / 20 (50% Cellex qSARS-CoV-2 IgG/IgM Cassette Dynamiker Biotechnology 2019-nCOV IgG/IgM Orient Gene Biotech COVID-19 IgG/IgM Rapid Test Cassette 11 / 20 (55% Prometheus Bio 2019-nCOV IgG/IgM In the subgroup of patients with time from symptom onset to sample collection >= 14 days, sensitivity and specificity of the LFA were 9/14 (64%; 95%CI 39-89) and 30/32 (94%; 95%CI 85-100), respectively, whereas sensitivity and specificity of the ELISA Of note, sensitivity was 17/24 (71%) in patients with >=7 days from symptom onset to sample collection and CRP >=100 mg/L We would like to thank our laboratory technicians and team managers for their assistance in performing the serological tests. This study aimed to assess the diagnostic performance of LFAs, and compare these to an enzyme-linked immunosorbent assay (ELISA) and NATs in suspected COVID-19 patients.
    keywords: covid-19; lfas; patients; rapid; sensitivity
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        item: #6902 of 7819
          id: cord-344609-sjekuh4d
      author: Devaraj, Anand
       title: Important lessons for infection control in radiology departments during the COVID-19 pandemic
        date: 2020-05-01
       words: 468
      flesch: 38
     summary: key: cord-344609-sjekuh4d authors: Devaraj, Anand title: Important lessons for infection control in radiology departments during the COVID-19 pandemic date: 2020-05-01 journal: Eur Radiol DOI: 10.1007/s00330-020-06873-y sha: doc_id: 344609 cord_uid: sjekuh4d nan Radiologists worldwide have benefited from the considerable volume of literature on the imaging appearances of COVID-19 pneumonia that has emerged from high-incidence centres in China. Politi et al [3] have produced guidance on the critically important subject of infection control in radiology departments.
    keywords: covid-19; radiology
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        item: #6903 of 7819
          id: cord-344647-jr85915d
      author: Joseph, Adrien
       title: Acute kidney injury in patients with SARS-CoV-2 infection
        date: 2020-09-03
       words: 3551
      flesch: 48
     summary: Last, high levels of PEEP in COVID-19 patients [34, 35] have also been suggested as a potential factor for increased AKI in severe COVID-19 patients [36] . Before adjustment, the third fraction of complement (C3), interleukin-6 (IL-6) and ferritin levels were higher in AKI patients.
    keywords: aki; complement; covid-19; infection; kidney; patients; study
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        item: #6904 of 7819
          id: cord-344653-to7571tw
      author: Whatley, Mary C.
       title: Younger and Older Adults’ Mood and Expectations Regarding Aging During COVID-19
        date: 2020-09-16
       words: 4995
      flesch: 51
     summary: In Study 1, older adults completed a mood and expectations regarding aging survey up to 2 years prior to the pandemic and again in April, 2020 (during the pandemic). Older adults’ mood and expectations regarding aging remained fairly constant, and younger adults showed lower mood and expectations regarding aging than did older adults, despite older adults showing greater concern about COVID-19.
    keywords: adults; aging; attitudes; covid-19; expectations; health; mood
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        item: #6905 of 7819
          id: cord-344658-4z2697q6
      author: Hutasoit, Novana
       title: Sars-CoV-2 (COVID-19) Inactivation Capability of Copper-Coated Touch Surface Fabricated by Cold-Spray Technology
        date: 2020-08-29
       words: 2479
      flesch: 48
     summary: To the best of the authors' knowledge, there is no study to investigate the behaviour of COVID-19 virus on cold-sprayed copper coatings, which is important as in-use components can be retrofitted with copper coatings and re-deployed in a very short period of time that can potentially slow down the spread of various viruses, including COVID-19. To facilitate the use of existing parts, cold-spray technique can be employed to deposit copper coatings in quick time.
    keywords: coating; copper; covid-19; push; steel; virus
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        item: #6906 of 7819
          id: cord-344682-4vpm7m1h
      author: Ellison, E Christopher
       title: Impact of the COVID-19 Pandemic on Surgical Training and Learner Well-Being: Report of a Survey of General Surgery and Other Surgical Specialty Educators
        date: 2020-09-12
       words: 6051
      flesch: 34
     summary: Few, if any, institutions were truly prepared to address the crisis in surgical training programs in the wake of the pandemic. A 37-item survey was distributed to educational leaders in general surgery and other surgical specialty training programs.
    keywords: covid-19; education; experience; impact; pandemic; programs; residents; respondents; stage; surgery; survey; training
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        item: #6907 of 7819
          id: cord-344688-uu3b529c
      author: Song, Xue-Jun
       title: Pain Management During the COVID-19 Pandemic in China: Lessons Learned
        date: 2020-04-22
       words: 2381
      flesch: 45
     summary: Of those infected, 22% were working in high risk departments such as infectious disease and intensive care units, while the majority (78%) worked in departments with less direct exposure to COVID-19 patients (9) . We may prepare ourselves to see more patients who previously had COVID-19 infection visiting pain clinic as the epidemic slows.
    keywords: care; covid-19; health; medical; pain; patients
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        item: #6908 of 7819
          id: cord-344693-znw3dru4
      author: Lima, Brian
       title: COVID‐19 in recent heart transplant recipients: Clinicopathologic features and early outcomes
        date: 2020-07-08
       words: 1845
      flesch: 33
     summary: To the best of our knowledge, the outcomes of HTx patients infected with COVID-19 within the early post-transplant period have not been previously reported, nor have the findings of electron microscopy to evaluate direct myocardial involvement of SARS-CoV-2 in immunosuppressed patients. Increased risk of severe illness is suggested by a recent study which reported a mortality rate of 25% among HTx patients with COVID-19 in a single transplant center.
    keywords: cases; covid-19; disease; heart; htx; patients; transplant
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        item: #6909 of 7819
          id: cord-344705-co0nk7pt
      author: Eichler, Hans‐Georg
       title: Clinical trials for Covid‐19: can we better use the short window of opportunity?
        date: 2020-05-14
       words: 2990
      flesch: 38
     summary: key: cord-344705-co0nk7pt authors: Eichler, Hans‐Georg; Cavaleri, Marco; Enzmann, Harald; Scotti, Francesca; Sepodes, Bruno; Sweeney, Fergus; Vamvakas, Spiros; Rasi, Guido title: Clinical trials for Covid‐19: can we better use the short window of opportunity? date: 2020-05-14 journal: Clin Pharmacol Ther DOI: 10.1002/cpt.1891 sha: doc_id: 344705 cord_uid: co0nk7pt This is not surprising; in the context of epidemics, academic groups, public health authorities, and funding bodies generally step up in their contribution to the crisis including design and conduction of clinical trials.
    keywords: covid-19; development; pandemic; patients; research; treatment; trials
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        item: #6910 of 7819
          id: cord-344709-5hy1e4t1
      author: Patel, Brijesh V.
       title: Pulmonary Angiopathy in Severe COVID-19: Physiologic, Imaging, and Hematologic Observations
        date: 2020-09-01
       words: 4519
      flesch: 32
     summary: Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus: a first step in understanding SARS pathogenesis SARS-coronavirus open reading Frame-3a drives multimodal necrotic cell death Thrombosis as an intravascular effector of innate immunity Eicosanoid storm in infection and inflammation Early intravascular events are associated with development of acute respiratory distress syndrome: a substudy of the LIPS-A clinical trial Natural history of venous thromboembolism Pandemic H1N1 influenza infection and vascular thrombosis Acute thrombotic vascular events complicating influenza-associated pneumonia Acute pulmonary embolism and COVID-19 pneumonia: a random association? COVID-19 complicated by acute pulmonary embolism Acute fibrinolysis shutdown after injury occurs frequently and increases mortality: a multicenter evaluation of 2,540 severely injured patients Fibrin derived from patients with chronic thromboembolic pulmonary hypertension is resistant to lysis Thromboelastography in patients with severe sepsis: a prospective cohort study The rate of deep vein thrombosis doubles in trauma patients with hypercoagulable thromboelastography Author disclosures are available with the text of this article at www.atsjournals.org. Dilated peripheral vessels were present in 21/33 (63.6%) patients with at least two assessable lobes (including 10/21 [47.6%] with no evidence of acute pulmonary emboli).
    keywords: acute; covid-19; dect; lung; patients; perfusion; pneumonia; vascular; vessels
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        item: #6911 of 7819
          id: cord-344714-0cam9ipf
      author: Russo, Maria
       title: Roles of flavonoids against coronavirus infection
        date: 2020-07-28
       words: 8426
      flesch: 41
     summary: The effect of quercetin on different viruses Activity of some flavonoids against viruses Antiviral effect of flavonoids on human viruses Vanden Berghe, Can ethnopharmacology contribute to the development of antiviral drugs? Effects of propolis flavonoids on virus infectivity and replication An in vitro study of theaflavins extracted from black tea to neutralize bovine rotavirus and bovine coronavirus infections Antiviral activity of quercetin 7-rhamnoside against porcine epidemic diarrhea virus In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells Procyanidins and butanol extract of Cinnamomi Cortex inhibit SARS-CoV infection SARS--beginning to understand a new virus Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activity Isotope dilution tandem mass spectrometric method for T4/T3 Binding interaction of quercetin-3-beta-galactoside and its synthetic derivatives with SARS-CoV 3CL(pro): structure-activity relationship studies reveal salient pharmacophore features Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition Flavonoid-mediated inhibition of SARS coronavirus 3C-like protease expressed in Pichia pastoris Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds of Psoralea corylifolia Geranylated flavonoids displaying SARS-CoV papain-like protease inhibition from the fruits of Paulownia tomentosa Evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors Characteristics of flavonoids as potent MERS-CoV 3C-like protease inhibitors Inhibition of SARS-CoV 3CL protease by flavonoids Chalcones isolated from Angelica keiskei inhibit cysteine proteases of SARS-CoV Dissection and identification of regions required to form pseudoparticles by the interaction between the nucleocapsid (N) and membrane (M) proteins of SARS coronavirus A facile inhibitor screening of SARS coronavirus N protein using nanoparticle-based RNA oligonucleotide Development of chemical inhibitors of the SARS coronavirus: viral helicase as a potential target NTPase/helicase by dihydroxychromone derivatives Synthesis and antiviral evaluation of 7-Oarylmethylquercetin derivatives against SARS-associated coronavirus (SCV) and hepatitis C virus (HCV) Identification of myricetin and scutellarein as novel chemical inhibitors of the SARS coronavirus helicase, nsP13 Traditional Chinese medicine for COVID-19 treatment Chemical composition and pharmacological mechanism of Qingfei Paidu Decoction and Ma Xing Shi Gan Decoction against Coronavirus Disease 2019 (COVID-19): In terms of public health, the 21st century has been characterized by coronavirus pandemics: in 2002-03 the virus SARS-CoV caused SARS; in 2012 MERS-CoV emerged and in 2019 a new human betacoronavirus strain, called SARS-CoV-2, caused the unprecedented COVID-19 outbreak.
    keywords: 3cl; activity; binding; coronavirus; cov; cov-2; covid-19; domain; flavonoids; host; infection; pro; protease; protein; quercetin; replication; residues; rna; sars; site
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        item: #6912 of 7819
          id: cord-344715-i7qxe40b
      author: Entress, Rebecca
       title: Managing Mass Fatalities during COVID‐19: Lessons for Promoting Community Resilience During Global Pandemics
        date: 2020-05-19
       words: 3743
      flesch: 48
     summary: New York City regularly uses mass graves when the deceased does not have family members or cannot afford a funeral (British Broadcasting Corporation With the rush of cremation, family members were left not knowing which funeral parlor to contact for the remains of their loved ones (Fifield and Li 2020).
    keywords: article; bodies; covid-19; family; fatality; haiti; mass; pandemic
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        item: #6913 of 7819
          id: cord-344729-sjjedgws
      author: Bhaskar, Sonu
       title: Acute Neurological Care in the COVID-19 Era: The Pandemic Health System REsilience PROGRAM (REPROGRAM) Consortium Pathway
        date: 2020-05-29
       words: 3717
      flesch: 36
     summary: • To ensure the quality of stroke care for COVID-19 stroke patients, such patients could be admitted to other wards for COVID-19 positive patients. However, these latter guidelines do not address the issue of separating COVID-19 patients from others in terms of scanning equipment, radiology suites, and decontamination protocols.
    keywords: acute; covid-19; healthcare; infection; management; pandemic; patients; stroke; workers
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        item: #6914 of 7819
          id: cord-344750-b9tndbg1
      author: Neumann-Böhme, Sebastian
       title: Once we have it, will we use it? A European survey on willingness to be vaccinated against COVID-19
        date: 2020-06-26
       words: 2774
      flesch: 46
     summary: To view a copy of this licence, visit http://creat iveco mmons .org/licen ses/by/4.0/. Compliance with anti-H1N1 vaccine among healthcare workers and general population Anti-vaccine activists, Web 2.0, and the postmodern paradigm-an overview of tactics and tropes used online by the anti-vaccination movement Luxembourg: Publications Office of the European Union Countering COVID-19: A European survey on acceptability and commitment to preventive measures World Health Organization: Draft of the landscape of COVID-19 candidate vaccines The race for coronavirus vaccines How can we develop a COVID-19 vaccine quickly? Game-theoretical reflections on communicating herd immunity in vaccine advocacy Social nudging: the effect of social feedback interventions on vaccine uptake s/VCP_The-State -of-Vacci ne-Confi dence _2015 Don't rush to deploy COVID-19 vaccines and drugs without sufficient safety guarantees Listen, understand, engage Can the world find a good covid-19 vaccine quickly enough ?
    keywords: covid-19; herd; immunity; population; vaccination; vaccine
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        item: #6915 of 7819
          id: cord-344778-2p1mm3vg
      author: Gasparri, Maria Luisa
       title: Changes in breast cancer management during the Corona Virus Disease 19 pandemic: an international survey of the European Breast Cancer Research Association of Surgical Trialists (EUBREAST)
        date: 2020-05-29
       words: 2690
      flesch: 43
     summary: COVID-19: elective triage guidelines for surgical care Intercollegiate general surgery guidance on COVID-19 update Coronavirus outbreak: Reorganising the breast unit during a pandemic Recommendations for prioritization, treatment, and triage of breast cancer patients during the COVID-19 pandemic. the COVID-19 pandemic breast cancer consortium Recommendations for triage, prioritization and treatment of breast cancer patients during the COVID-19 pandemic Covid-19: Four Fifths of Cases Are Asymptomatic, China Figures Indicate Clinical Characteristics of 138 Hospitalized Patients With Novel Coronavirus-Infected Pneumonia in Wuhan, China.
    keywords: breast; cancer; chemotherapy; covid-19; pandemic; patients
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        item: #6916 of 7819
          id: cord-344813-dlpn3l0j
      author: Chen, Cheng‐Ren
       title: Preparing for COVID‐19: The experiences of a long‐term care facility in Taiwan
        date: 2020-07-21
       words: 1463
      flesch: 45
     summary: Dear Editor, Two aspects warrant consideration regarding the ongoing COVID-19 pandemic: prevention of COVID-19 infection and protection from the related changes among the elderly. There might be an association between angiotensin-converting enzyme (ACE) 2 levels and COVID-19 infection, 2 and obese and diabetic patients may have increased ACE2 levels.
    keywords: care; covid-19; facility; government; residents
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        item: #6917 of 7819
          id: cord-344817-8xz7xbh1
      author: Hens, Niel
       title: The COVID-19 epidemic, its mortality, and the role of non-pharmaceutical interventions
        date: 2020-04-30
       words: 2460
      flesch: 52
     summary: It is not merely numbers but also the severity of cases, even when non-fatal. Further, the earlier that contact rates are drastically reduced (severe social distancing), the better.
    keywords: cases; covid-19; epidemic; number; rate
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        item: #6918 of 7819
          id: cord-344824-myaiilra
      author: Sha, D.
       title: Spatiotemporal Analysis of Medical Resource Deficiencies in the U.S. under COVID-19 Pandemic
        date: 2020-05-25
       words: 5741
      flesch: 48
     summary: [9, 10] . Are U.S. medical resources enough to handle the worst scenario during this crisis? MRDId is large (>1) when local medical resources cannot fully support the hospitalized critically ill patients, or the local medical burden is heavy; and MRDId is small (<1) when local medical resources are sufficient.
    keywords: beds; care; county; covid-19; data; icu; level; medrxiv; number; preprint
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        item: #6919 of 7819
          id: cord-344829-adlp2rjy
      author: de Rivero Vaccari, Juan Carlos
       title: The Inflammasome in Times of COVID-19
        date: 2020-10-08
       words: 8734
      flesch: 27
     summary: Ionic imbalance has been associated with inflammasome activation in the lung following infections (64) , and consistent with this finding is a recent study by Nieto-Torres et al. showing that E protein from SARS-CoV makes a Ca 2+ permeable channel in the endoplasmic reticulum (ER)/Golgi intermediate compartment (ERGIC)/Golgi membrane that results in NLRP3 inflammasome activation and increased levels of IL-1β (Figure 3 ) (46). However, in regards to inflammasome activation, it seems that ORF3a promotes NLRP3 inflammasome activation by modulating the ubiquitination of the inflammasome adaptor protein ASC and the production of pro-IL-1β by activation of NF-κB, which is independent of the ion-channel role that ORF3a plays.
    keywords: activation; acute; covid-19; il-1β; infections; inflammasome; inflammatory; injury; levels; lung; nlrp3; patients; pneumonia; protein; response; role; sars; syndrome
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        item: #6920 of 7819
          id: cord-344853-s2p2csrx
      author: Hendren, Nicholas S.
       title: Description and Proposed Management of the Acute COVID-19 Cardiovascular Syndrome
        date: 2020-04-16
       words: 6698
      flesch: 27
     summary: Med J Chinese People's Liberation Army Pulmonary pathology of early-phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer Pathological study of impact of SARS coronavirus on heart and its conduction system in SARS patients. In this document, we focus on a prominent myocarditis-like syndrome involving acute myocardial injury often associated with reduced left ventricular ejection fraction in the absence of obstructive coronary artery disease.
    keywords: acovcs; acute; cardiac; coronavirus; cov-2; covid-19; disease; heart; injury; myocarditis; patients; sars; syndrome
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        item: #6921 of 7819
          id: cord-344909-0o55l4iy
      author: Cross, Robert W.
       title: Use of convalescent serum reduces severity of COVID-19 in nonhuman primates
        date: 2020-10-14
       words: 5723
      flesch: 40
     summary: Differences in clinical parameters of the LD-treated group with untreated control animals from this study or historical control animals were minimal; however, the lack of infectious SARS-CoV-2 in the BAL samples from all of the LD-treated animals and reduced lung pathology suggest that an antiviral effect was present despite the lower concentration of neutralizing antibodies in the dose of convalescent sera administered. Prothrombin time (PT) was largely unaffected, yet a significantly prolonged coagulation time was noted at 4 dpi for activated partial thromboplastin time (aPTT) in HD versus control group (p=0.0459; two-way ANOVA with Tukey's multiple comparison); decreases in levels of thrombocytes were more notable in control animals; and increases in circulating fibrinogen were generally more pronounced in the control group compared to either of the experimental groups ( Figure S1 ).
    keywords: animals; control; convalescent; cov-2; covid-19; dpi; et al; sars; sera; treatment
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        item: #6922 of 7819
          id: cord-344911-pw0ghz3m
      author: July, Julius
       title: Impact of the coronavirus disease pandemic on the number of strokes and mechanical thrombectomies: A systematic review and meta-analysis: COVID-19 and Stroke Care
        date: 2020-07-22
       words: 2125
      flesch: 41
     summary: The number of mechanical thrombectomies per stroke patient was higher during the pandemic (OR 1.23 [1.12-1.36], p<0.001; I(2): 0%, p=0.845). However, the number of mechanical thrombectomies per stroke patient was higher during the pandemic (OR 1.23 [1.12-1.36], p<0.001; I 2 : 0%, p=0.845).
    keywords: analysis; covid-19; number; pandemic; stroke
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        item: #6923 of 7819
          id: cord-344939-rgxqobfw
      author: Ng, C. W. Q.
       title: Maintaining breast cancer care in the face of COVID‐19
        date: 2020-08-24
       words: 1482
      flesch: 38
     summary: The UK Standardisation of Breast Radiotherapy (START) trials of radiotherapy hypofractionation for treatment of early breast cancer: 10-year follow-up results of two randomised controlled trials International guidelines on radiation therapy for breast cancer during the COVID-19 pandemic COVID-19: Global radiation oncology's targeted response for pandemic preparedness The authors acknowledge the breast care team at National University Hospital for collating the operational numbers used to complete Table 1 , and for their continued efforts to provide the best care for patients. Systems are strained though adequate, with significant rerouting of resources to COVID-19 care.
    keywords: breast; cancer; care; covid-19; patients
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        item: #6924 of 7819
          id: cord-344948-cve3mqd8
      author: Adhikari, Jagannath
       title: COVID-19 impacts on agriculture and food systems in Nepal: Implications for SDGs
        date: 2020-11-07
       words: 6623
      flesch: 42
     summary: The Kathmandu Post Against-all-odds-what-driving-poverty-reduction-Nepal COVID-19 will double number of people facing food crises unless swift action is taken COVID-19 coronavirus pandemic Berrang-Ford, L., the Indigenous Health Climate change and COVID-19: reinforcing indigenous food systems We acknowledge Nepalese Association of Agriculture, Forestry and Environment in Australia (NEPAFE) for hosting the panel discussions and the Institute for Study and Development Worldwide (IFSD), Sydney for in-kind support in literature review, virtual discussions, and interviews. Key Informants -Government policy makers (2) 1) Mid-April 2020 (10) 2) Mid-Oct 2020 (10) Government policies to deal with such crisis; what supports are provided, how and to whom; policy gaps in agricultural sector in general and food security in particular as exposed by the crisis; experience/idea with regard to resiliency of prevailing farming systems to cope with such crisis; role of indigenous food systems in such crisis; what new initiatives taken at different government levels to deal with the crisis and continue with food production, marketing, distribution through trade/transportation, supply of inputs, new incentive structures; effectiveness of these new initiatives and which seem to work effectively; what could be the policies options for the future to deal with the crisis.
    keywords: covid-19; crisis; farmers; farming; food; government; nepal; pandemic; people; production; security; support; systems
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        item: #6925 of 7819
          id: cord-344949-9zyz4hll
      author: Luban, Jeremy
       title: The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines
        date: 2020-08-05
       words: 5571
      flesch: 36
     summary: Normalized percent numbers of nucleocapsid positive cells were plotted against Log10 transforms of PTC299 concentrations and the IC50 was estimated using non-linear regression (goodness-of-fit R-squared = 0.9653). The percentages in red denote the respective extents to which the relative levels of specific nucleotides are reduced during PTC299 treatment (100 nM) of cultured HT1080 fibrosarcoma cells for 8 hours (Cao et al., 2019)
    keywords: cells; cov-2; covid-19; culture; et al; production; ptc299; replication; sars; system
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        item: #6926 of 7819
          id: cord-344970-ud1lhkyi
      author: Fecchi, Katia
       title: Coronavirus Interplay With Lipid Rafts and Autophagy Unveils Promising Therapeutic Targets
        date: 2020-08-11
       words: 5443
      flesch: 25
     summary: In contrast, Gassen et al. reported that MERS-CoV activates the SKP2 kinase, consequently reducing Beclin1 (BECN1) activity and inhibiting the fusion of autophagosomes with lysosomes, which results in autophagy inhibition (Gassen et al., 2019) . In general, it has been hypothesized that coronaviruses would induce accumulation of autophagic vacuoles to obtain a larger availability of the membrane structure necessary for their replication (Gassen et al., 2019) , which is consistent to the observed co-localization of the rodent coronavirus, MHV, replication complex, with the autophagic proteins LC3 and Apg12 (Prentice et al., 2004) .
    keywords: autophagy; cell; coronavirus; covid-19; entry; et al; host; human; hydroxychloroquine; infection; lipid; membrane; rafts; replication; sars; viruses
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        item: #6927 of 7819
          id: cord-344978-m672rnze
      author: Chen, Yuntian
       title: A Quantitative and Radiomics approach to monitoring ARDS in COVID-19 patients based on chest CT: a retrospective cohort study
        date: 2020-07-06
       words: 3968
      flesch: 44
     summary: Acute respiratory distress syndrome (ARDS) is the major cause of severe cases, and early detection and early treatment of ARDS patients could improve the outcome [9, 10] . key: cord-344978-m672rnze authors: Chen, Yuntian; Wang, Yi; Zhang, Yuwei; Zhang, Na; Zhao, Shuang; Zeng, Hanjiang; Deng, Wen; Huang, Zixing; Liu, Sanyuan; Song, Bin title: A Quantitative and Radiomics approach to monitoring ARDS in COVID-19 patients based on chest CT: a retrospective cohort study date: 2020-07-06 journal: Int J Med Sci DOI: 10.7150/ijms.48432 sha: doc_id: 344978 cord_uid: m672rnze Rationale: Acute respiratory distress syndrome (ARDS) is one of the major reasons for ventilation and intubation management of COVID-19 patients but there is no noninvasive imaging monitoring protocol for ARDS.
    keywords: ards; covid-19; existence; features; model; patients; radiomics; sets
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        item: #6928 of 7819
          id: cord-344985-3mu9rrql
      author: Fakhruddin, Bapon
       title: Are we there yet? The transition from response to recovery for the COVID-19 pandemic
        date: 2020-05-12
       words: 4305
      flesch: 41
     summary: Transitioning from pandemic response to recovery in a spiral fashion: there is a high probability of the second and even the third wave of a pandemic if there is no vaccine or immunization, each new wave pushing the disaster risk reduction cycle from the recovery back to response phase. Ensuring consideration at all levels on government response, policies, plans and logistics regarding the process in which they respond to other emergencies during the pandemic, whilst ensuring scientific harmony, is crucial in ensuring effective response, recovery times, and financial and political stability.
    keywords: covid-19; disaster; hazards; health; pandemic; phase; public; recovery; response; risk
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        item: #6929 of 7819
          id: cord-344986-nknt413b
      author: Heymann, D L
       title: Successful smallpox eradication: what can we learn to control COVID-19?
        date: 2020-05-30
       words: 1686
      flesch: 45
     summary: There were several generations of smallpox vaccines, all very efficacious but also with substantial safety concerns. Speaking at a virtual event hosted at WHO-HQ to celebrate the 40 year anniversary of smallpox eradication, WHO Director-General Dr Tedros Adhanom Ghebreyesus said, As the world confronts the COVID-19 pandemic, humanity's victory over smallpox is a reminder of what is possible when nations come together to fight a common health threat.
    keywords: covid-19; eradication; health; smallpox
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        item: #6930 of 7819
          id: cord-345040-cuau2dcy
      author: Alom, Samiha
       title: Use of ECMO in COVID-19 patients: Does the evidence suffice?
        date: 2020-07-30
       words: 2709
      flesch: 40
     summary: key: cord-345040-cuau2dcy authors: Alom, Samiha; Haiduc, Ana Alina; Melamed, Naomi; Axiaq, Ariana; Harky, Amer title: Use of ECMO in COVID-19 patients: Does the evidence suffice? date: 2020-07-30 journal: J Cardiothorac Vasc Anesth DOI: 10.1053/j.jvca.2020.07.070 sha: doc_id: 345040 cord_uid: cuau2dcy nan Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has gathered worldwide attention for its potentially fatal course and complex clinical manifestations. In this letter, we have performed a systematic review of literature to summarize the evidence behind using ECMO in COVID-19 patients.
    keywords: covid-19; ecmo; extracorporeal; membrane; oxygenation; patients
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        item: #6931 of 7819
          id: cord-345059-t6hojshj
      author: Bayoumy, A. B.
       title: Unrealized potential of drug repositioning in europe during COVID-19 and beyond: a physcian’s perspective
        date: 2020-07-17
       words: 5425
      flesch: 42
     summary: The advantages of drug repositioning are that it benefits patients and that it adds new indications to existing drugs for lower costs compared to de novo drug development. The current framework for drug repositioning allows “venture capital” companies to abuse loopholes in the legislation to gain long-term market authorization among with excessive high pricing.
    keywords: authorization; covid-19; data; drug; drug repositioning; market; orphan; patients; repositioning; thalidomide; treatment
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        item: #6932 of 7819
          id: cord-345064-it26ygo6
      author: Lotzin, Annett
       title: Stressors, coping and symptoms of adjustment disorder in the course of the COVID-19 pandemic – study protocol of the European Society for Traumatic Stress Studies (ESTSS) pan-European study
        date: 2020-08-27
       words: 4693
      flesch: 39
     summary: Following a conceptual framework based on the WHO’s social framework of health, an assessment of risk and resilience factors, COVID-19 related stressors and pandemic-specific coping behaviours will be measured to estimate their contribution to symptoms of adjustment disorder. It is assumed that the selected risk factors, resilience factors and stressors are significantly associated with severity of adjustment disorder symptoms at T1 and T2.
    keywords: adjustment; covid-19; disorder; e.g.; factors; health; pandemic; resilience; risk; social; stressors; study; symptoms
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        item: #6933 of 7819
          id: cord-345065-5520ckdr
      author: Maalouf, Fadi T.
       title: Mental health research in response to the COVID-19, Ebola, and H1N1, outbreaks: a comparative bibliometric analysis
        date: 2020-10-28
       words: 3937
      flesch: 39
     summary: It was not surprising that the number of publications on COVID-19 related mental health publications was much higher than that of the other two outbreaks combined. key: cord-345065-5520ckdr authors: Maalouf, Fadi T.; Medawar, Bernadette; Meho, Lokman I.; Akl, Elie A. title: Mental health research in response to the COVID-19, Ebola, and H1N1, outbreaks: a comparative bibliometric analysis date: 2020-10-28 journal: J Psychiatr Res DOI: 10.1016/j.jpsychires.2020.10.018 sha: doc_id: 345065 cord_uid: 5520ckdr INTRODUCTION: Both the COVID-19 pandemic and its management have had a negative impact on mental health worldwide.
    keywords: coronavirus; covid-19; h1n1; health; mental; pandemic; research
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        item: #6934 of 7819
          id: cord-345067-kummh0g7
      author: Nachega, Jean B.
       title: Mobile Health Technology for Enhancing the COVID-19 Response in Africa: A Potential Game Changer?
        date: 2020-05-29
       words: 1180
      flesch: 46
     summary: How USSD Code Is Breaking Grounds in Ghana -Part COVID-19: Our Response in Senegal South Africa Is Hunting Down Coronavirus with Thousands of Health Workers Mobile phone-delivered reminders and incentives to improve childhood immunisation coverage and timeliness in Kenya (M-SIMU): a cluster randomised controlled trial A hybrid mobile approach for populationwide HIV testing in rural east Africa: an observational study Controlling ebola through mHealth strategies COVID-19 AND MOBILE HEALTH TECHNOLOGY IN AFRICA [4] [5] [6] The Global System for Mobile Communication Association reports that 50% of Africans own mobile phones and that 39% are internet-connected, numbers which are rapidly increasing, and approach 80% access when phone-sharing is considered.
    keywords: africa; covid-19; health; mobile; technology
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        item: #6935 of 7819
          id: cord-345083-f2jzho3i
      author: Gachohi, John
       title: Public health challenges posed by delays in obtaining COVID-19 clearance for long-distance truckers across East Africa
        date: 2020-10-24
       words: 1044
      flesch: 20
     summary: Covid-19 Status Dashboard Uganda's first 100 COVID-19 cases: Trends and lessons The first confirmed case of COVID-19 in Tanzania: Recommendations based on lesson learned from China Tanzania registers first coronavirus death Uganda coronavirus: first death registered, cases reach 1,079 Truck drivers weak link as Covid-19 numbers surge Lessons learnt from easing COVID-19 restrictions: an analysis of countries and regions in Asia Pacific and Europe Viral dynamics in mild and severe cases of COVID-19 Hiv testing preferences among long distance truck drivers in kenya: a discrete choice experiment Asymptomatic transmission, the achilles' heel of current strategies to control Covid-19 Health Risks of American Long Distance Truckers: Results from a Multi-Site Assessment COVID-19 outbreak on the Diamond Princess cruise ship: estimating the epidemic potential and effectiveness of public health countermeasures The characterization of feces and urine: A review of the literature to inform advanced treatment technology Variation in childhood diarrheal morbidity and mortality in Africa Seroprevalence and associated risk factors of leptospirosis in slaughter pigs; A neglected public health risk, western Kenya Ross, macdonald, and a theory for the dynamics and control of mosquito-transmitted pathogens The management of diabetes in conflict settings: Focus on the Syrian crisis Revisiting the understanding of transactional sex in sub-Saharan Africa: A review and synthesis of the literature The estimated incidence of induced abortion in Kenya: A cross-sectional study Global disability-adjusted life-year estimates of long-term health burden and undernutrition attributable to diarrhoeal diseases in children younger than 5 years Irritable Bowel Syndrome: Modern Concepts and Management Options Transactional sex and risk for HIV infection in sub-Saharan Africa: A systematic review and meta-analysis Original Draft: JG Writing -Review & Editing: All Supervision and Project Administration: SK Funding acquisition: Not Applicable J Manuscript title: Public health challenges posed by delays in obtaining COVID-19 clearance for long-distance truckers across East AfricaThe authors whose names are listed immediately below certify that they have NO affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers' bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript. key: cord-345083-f2jzho3i authors: Gachohi, John; Aduda, Jane; Thuo, Reuben; Mung'atu, Joseph; Wamunyokoli, Fred; Ngigi, Thomas; Athiany, Henry; Kikuvi, Gideon; Mambo, Susan; Gichaiya, Wairimu; Matheri, Joseph; Mburugu, Patrick; Simba, Justus; Otiwa, Carol; Muriuki, Charles; Mwaura, Joshua; Yariwo, May; Kariuki, Beatrice; Machua, Joseph; Mwangi, Catherine; Amoth, Patrick; Aman, Rashid; Kamau, Onesmus; Muthoka, Kennedy; Otieno, Jacob; Mwele, Pascal; Nzioka, Rose; Karanja, Simon title: Public health challenges posed by delays in obtaining COVID-19 clearance for long-distance truckers across East Africa date: 2020-10-24 journal: Glob Epidemiol DOI: 10.1016/j.gloepi.2020.100039 sha: doc_id: 345083 cord_uid: f2jzho3i nan COVID-19 related death on March 26, 2020 1 , followed by Tanzania on March 31, 2020 4 , and Uganda on July 23, 2020 5 .
    keywords: cases; covid-19; health; interest; risk
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        item: #6936 of 7819
          id: cord-345092-1ztfcpsb
      author: Iwasaki, Masae
       title: Inflammation Triggered by SARS-CoV-2 and ACE2 Augment Drives Multiple Organ Failure of Severe COVID-19: Molecular Mechanisms and Implications
        date: 2020-10-08
       words: 11452
      flesch: 39
     summary: Retrospective study Structure analysis of the receptor binding of 2019-nCoV. Biochemical and Biophysical Research Communications Kidney disease is associated with in-hospital death of patients with COVID-19 A simple approximate mathematical model to predict the number of severe acute respiratory syndrome cases and deaths Cytokine storm and sepsis disease pathogenesis Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis Angiotensin II activates programmed myocyte cell death in vitro Activation of the AT(2) receptor of angiotensin II induces neurite outgrowth and cell migration in microexplant cultures of the cerebellum Nitric oxide, a new second messenger involved in the action of angiotensin II on neuronal differentiation of NG108-15 cells The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19) Effect of ACE2 and angiotensin-(1-7) in a mouse model of early chronic kidney disease Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: Implications for pathogenesis and virus transmission pathways Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin system The spike protein of SARS-CoV-a target for vaccine and therapeutic development The Apelin-APJ axis is an endogenous counterinjury mechanism in experimental acute lung injury Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV-2 infection Acute respiratory distress syndrome: The Berlin definition Renin-angiotensin system revisited Diagnostic utility of clinical laboratory data determinations for patients with the severe COVID-19 Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding Kawasaki disease complicated with macrophage activation syndrome: A systematic review Hydroxychloroquine and azithromycin as a treatment of COVID-19: Results of an open-label nonrandomized clinical trial The spike protein of the emerging betacoronavirus EMC uses a novel coronavirus receptor for entry, can be activated by TMPRSS2, and is targeted by neutralizing antibodies A review of urinary angiotensin converting enzyme 2 in diabetes and diabetic nephropathy Evidence that TMPRSS2 activates the severe acute respiratory syndrome coronavirus spike protein for membrane fusion and reduces viral control by the humoral immune response Remdesivir for 5 or 10 days in patients with severe covid-19 Compassionate use of remdesivir for patients with severe covid-19 Clinical characteristics of coronavirus disease 2019 in China Cryo-electron microscopy structures of the SARS-CoV spike glycoprotein reveal a prerequisite conformational state for receptor binding Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 TACE antagonists blocking ACE2 shedding caused by the spike protein of SARS-CoV are candidate antiviral compounds Modulation of TNF-alpha-converting enzyme by the spike protein of SARS-CoV and ACE2 induces TNF-alpha production and facilitates viral entry The emerging role of ACE2 in physiology and disease Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. This review summarizes the current evidence and understanding of the underlying mechanisms of SARS-CoV-2, ACE2 and inflammation co-mediated multi-organ injury or failure in COVID-19 patients.
    keywords: ace2; acute; ang2; angiotensin; cells; coronavirus; cov-2; covid-19; covid-19 patients; cytokine; disease; host; il-6; infection; injury; lung; patients; protein; receptor; sars; study; syndrome
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        item: #6937 of 7819
          id: cord-345108-gtp36snr
      author: Al-Ani, Raid M.
       title: Prevalence of Anosmia and Ageusia in Patients with COVID-19 at a Primary Health Center, Doha, Qatar
        date: 2020-08-19
       words: 3255
      flesch: 58
     summary: The study was a retrospective analysis of the prevalence of the anosmia and ageusia in COVID-19 patients. The mystery and the miracle Organization WH (2020) WHO Director-General's remarks at the media briefing on 2019-nCoV on 11 Covid-19: WHO declares pandemic because of 'alarming levels' of spread, severity, and inaction Loss of smell and taste in combination with other symptoms is a strong predictor of COVID-19 infection Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Clinical features of 69 cases with coronavirus disease in Wuhan China COVID-19 and Anosmia in Tehran Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study Loss of sense of smell as marker of COVID-19 infection, ENT UK Olfactory and gustatory dysfunction as an early identifier of COVID-19 in adults and children: An international multicenter study Olfactory dysfunction and sinonasal symptomatology in COVID-19: prevalence, severity, timing, and associated characteristics Olfactory and gustatory outcomes in COVID-19: A prospective evaluation in nonhospitalized subjects The prevalence of olfactory and gustatory dysfunction in COVID-19 patients: a systematic review and meta-analysis Prevalence and recovery from olfactory and gustatory dysfunctions in Covid-19 infection: a prospective multicenter study Smell and taste abnormalities due to
    keywords: ageusia; anosmia; covid-19; disease; patients; study
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        item: #6938 of 7819
          id: cord-345114-b06uz0sj
      author: Klinger, Danielle
       title: Significantly Improved COVID-19 Outcomes in Countries with Higher BCG Vaccination Coverage: A Multivariable Analysis
        date: 2020-07-11
       words: 6993
      flesch: 46
     summary: Supplementary Materials: The following are available online at http://www.mdpi.com/2076-393X/8/3/378/s1, Figure S1 : correlation of BCG years of admission and COVID-19 outcomes for countries bounded by a population size of >100 M, Figure S2 : results from a multivariable analysis for countries bounded by a population size of >100 M, Table S1 : variable resources across countries and populations, Table S2 : additional resources on BCG administration years by country, Table S3 : country cohort of 55 countries used in the study, Table S4 : correlations and p-values of regression of years of BCG administrations and different outcomes including permutation tests, Table S5 : multivariable results at numerous time points for BCG years of admission, Table S6 : Sub-sampling of countries for years of BCG administration and COVID-19 outcome, Text S1: The results from multivariable regression tests with 23 economic, demographic, health-related, and pandemic restriction-related quantitative properties, substantiate the dominant contribution of BCG years to the COVID-19 outcomes.
    keywords: age; bcg; correlation; countries; covid-19; dpm; figure; group; population; years
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        item: #6939 of 7819
          id: cord-345125-s96xufes
      author: McCloskey, Brian
       title: Mass gathering events and reducing further global spread of COVID-19: a political and public health dilemma
        date: 2020-03-20
       words: 1757
      flesch: 30
     summary: World Health Organization Effects of response to 2014-2015 Ebola outbreak on deaths from malaria, HIV/AIDS, and tuberculosis, west Africa Evidence of SARS-CoV-2 infection in returning travelers from Wuhan, China Preparedness and vulnerability of African countries against importations of COVID-19: a modelling study Malaria morbidity and mortality in Ebola-affected countries caused by decreased health-care capacity, and the potential effect of mitigation strategies: a modelling analysis Impact of the Mass Drug Administration for malaria in response to the Ebola outbreak in Sierra Leone Malaria control campaign launched in Democratic Republic of the Congo to save lives and aid Ebola response COVID-19) outbreak Public health for mass gatherings: key considerations Mass gatherings medicine: public health issues arising from mass gathering religious and sporting events Global mass gatherings: implications and opportunities for global health security Mass gatherings medicine: international cooperation and progress Olympic and Paralympic Games: public health surveillance and epidemiology European Football Championship finals: planning for a health legacy Hosting of mass gathering sporting events during the 2013-2016 Ebola virus outbreak in west Africa: experience from three African countries Rapid spread of Zika virus in the Americas-implications for public health preparedness for mass gatherings at the 2016 Brazil Olympic Games Saudi Arabia's measures to curb the COVID-19 outbreak: temporary suspension of the Umrah pilgrimage Transmission of respiratory tract infections at mass gathering events Toning down the 2019-nCoV media hype and restoring hope Hajj: infectious disease surveillance and control Key planning recommendations for mass gatherings in the context of the current COVID-19 outbreak. Action plans should include: WHO, working with global partners in MG health, many of whom were involved in the Riyadh conferences and The Lancet's 2014 Mass Gatherings Medicine Series, [4] [5] [6] [7] 13 has developed comprehensive recommendations for managing the public health aspects of MGs that have been updated with interim key recommendations for COVID-19.
    keywords: assessment; covid-19; health; mgs; public; risk
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        item: #6940 of 7819
          id: cord-345139-gyvlikye
      author: Izquierdo-Domínguez, Adriana
       title: Pérdida del sentido del olfato durante la pandemia COVID-19
        date: 2020-06-12
       words: 2889
      flesch: 37
     summary: La disfunción olfatoria (DO) se puede clasificar en cuantitativa, que implica alteración en la intensidad, o cualitativa, en la que cambia la calidad de la percepción de los olores. y tiene por objeto el estudio de las variaciones olfativas en función de la concentración de la sustancia olorosa y de la cantidad de los olores detectados, dando un resultado de anosmia (pérdida total), hiposmia (pérdida parcial)
    keywords: anosmia; como; con; cov-2; covid-19; del; estudio; las; los; mediante; olfativo; olfato; olores; pacientes; para; patients; por; pérdida; que; sars; una
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        item: #6941 of 7819
          id: cord-345180-i4syz2t1
      author: He, M.
       title: A delayed modulation of solar radiation on the COVID-19 transmission reflects an incubation period
        date: 2020-10-14
       words: 3981
      flesch: 45
     summary: The canonical correlation coefficient is close to the correlation of UV r UV =-0.55±0.08 (Figure 2a) , which implicates that using both the UV and temperature as predictors can not explain more variance of the growth rate than using the UV alone. In Figure 1 , Africa, central Asia and Central America are generally associated with low least-constrained growth rates, whereas high growth rates are observed in middle and high latitudes of North America and Europe.
    keywords: correlation; covid-19; growth; growth rate; rate; temperature
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        item: #6942 of 7819
          id: cord-345184-0otbz5xo
      author: Mamani, Percy G Ruiz
       title: Propiedades de una escala de preocupación por el COVID-19: Análisis exploratorio en una muestra peruana
        date: 2020-07-09
       words: 1960
      flesch: 45
     summary: Los resultados del AFE son similares a los que se reportaron en el estudio de validación de la escala de preocupación por el cáncer (EPC), versión española Se evaluó la adecuación de la muestra a través de la prueba de esfericidad de Bartlett, donde un valor de p < 0.05 indicaría que la matriz es adecuada debido a las correlaciones altas entre las variables y
    keywords: análisis; con; covid-19; las; los; por; preocupación; que; una
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        item: #6943 of 7819
          id: cord-345191-nabxpyw3
      author: Bell, Sadie
       title: Parents’ and guardians’ views on the acceptability of a future COVID-19 vaccine: a multi-methods study in England
        date: 2020-10-19
       words: 1958
      flesch: 37
     summary: To prevent inequalities in uptake, it is crucial to understand and address factors that may affect COVID-19 vaccine acceptability in ethnic minority and lower-income groups who are disproportionately affected by COVID-19. The following reasons were given for COVID-19 vaccine acceptance for self and for 253 child/children, in order of how often they were mentioned by survey participants and 254 importance to interviewees.
    keywords: child; covid-19; participants; vaccine; views
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        item: #6944 of 7819
          id: cord-345198-avnxgwwj
      author: Amir-Behghadami, Mehrdad
       title: Iranian national COVID-19 electronic screening system: experience to share
        date: 2020-05-19
       words: 705
      flesch: 49
     summary: key: cord-345198-avnxgwwj authors: Amir-Behghadami, Mehrdad; Janati, Ali title: Iranian national COVID-19 electronic screening system: experience to share date: 2020-05-19 journal: Emerg Med J DOI: 10.1136/emermed-2020-209806 sha: doc_id: 345198 cord_uid: avnxgwwj nan Iranian national COVID-19 electronic screening system: experience to share Iranian health authorities confirmed the first cases of coronavirus on 19 February 2020 in Qom. gov. ir-and the rest through the information of electronic health dossiers and 4030 phone calls.
    keywords: citizens; health
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        item: #6945 of 7819
          id: cord-345204-ch0e6lzl
      author: Scarlata, S.
       title: Design Of A Rapid And Reversible Fluorescence Assay To Detect COVID-19 And Other Pathogens
        date: 2020-10-05
       words: 2920
      flesch: 54
     summary: To optimize beacon use, it is useful to estimate the density of beacon that must be attached to a test strip. Previously, our lab has used molecular beacons to isolate stem cells induced to express exogenous genes [3] .
    keywords: beacon; covid-19; fluorescence; mrna; rna; saliva; stem
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        item: #6946 of 7819
          id: cord-345225-2s5xd1oc
      author: Soares, F.
       title: A novel high specificity COVID-19 screening method based on simple blood exams and artificial intelligence
        date: 2020-04-14
       words: 4559
      flesch: 46
     summary: Hospitals would be able to provide better isolation of COVID-19 patients, given that blood samples could be drawn on a daily basis and ER-CoV would identify patients that should be moved to another ward, for instance a ward of suspected positive patients. However, previous studies already identified that C reactive protein (Ling, 2020) , leukocytes (Cheng et al., 2020; Qin et al., 2020) , platelets (Cheng et al., 2020) , and lymphocytes (Xu et al., 2020) are altered at different levels in COVID-19 patients.
    keywords: cov-2; covid-19; license; negative; patients; preprint; sars
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        item: #6947 of 7819
          id: cord-345267-u24g6607
      author: Lang, Frederick M.
       title: GM-CSF-based treatments in COVID-19: reconciling opposing therapeutic approaches
        date: 2020-06-23
       words: 6022
      flesch: 19
     summary: This Perspective discusses the pleiotropic biology of GM-CSF and the scientific merits behind these contrasting approaches. mutations that ablate GM-CSFR function) causes pulmonary alveolar proteinosis (PAP), a life-threatening interstitial lung disease in which dysfunctional alveolar macrophages cannot clear surfactant 16 . GM-CSFR is mainly expressed on myeloid cells, generally restricting the direct-acting function of GM-CSF to cells of this lineage.
    keywords: acute; cells; colony; covid-19; csf; cytokine; disease; factor; lung; macrophage; myeloid; patients
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        item: #6948 of 7819
          id: cord-345288-qyz83xx2
      author: Pata, Francesco
       title: Enteral stoma care during COVID‐19 pandemic: practical advice
        date: 2020-07-21
       words: 2701
      flesch: 39
     summary: Viral RNA has been detected in the faeces of COVID-19 patients 28 and potential transmission during enteral stoma manipulation cannot be excluded. Several recommendations advocate that for high-risk operations stoma formation instead of primary anastomosis should be considered to reduce the risk of complications 14,15,20-22 , need of ICU facilities which are already overwhelmed by COVID-19 patients, and hospital stay.
    keywords: care; covid-19; healthcare; pandemic; patients; risk; sars; stoma
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        item: #6949 of 7819
          id: cord-345298-1hdk14xg
      author: Massari, Francesco
       title: Oncology clinical trials in the time of COVID-19: how a pandemic can revolutionize patients’ care
        date: 2020-05-14
       words: 1247
      flesch: 35
     summary: Indeed, recent studies show that cancer patients present a higher risk of COVID-19 infection (odds ratio: 2.31; 95% Cl: 1.89-3.02) and of severe events from COVID-19 [5, 6] . Every effort should be made, both from clinicians and pharmaceutical companies, not to limit treatment chances for cancer patients and to concomitantly protect their safety.
    keywords: covid-19; patients; treatment
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        item: #6950 of 7819
          id: cord-345304-n74m5ucs
      author: Safadi, Marco Aurelio Palazzi
       title: THE CHALLENGING AND UNPREDICTABLE SPECTRUM OF COVID-19 IN CHILDREN AND ADOLESCENTS
        date: 2020-09-07
       words: 1856
      flesch: 31
     summary: 11 One of the most important Latin American reference centers for pediatric liver diseases and pediatric liver transplantation in Brazil described their experience with 169 non-transplant children and adolescents suspected and tested for SARS-CoV-2. Infants <1 year of age and children with chronic pulmonary diseases (including moderate to severe asthma), cardiovascular illnesses (including congenital heart disease), malignancy, immunosuppression and obesity appear to be at increased risk of severe disease.
    keywords: adolescents; children; cov-2; covid-19; disease; sars
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        item: #6951 of 7819
          id: cord-345315-y3bdjnhg
      author: Dai, Yaoyao
       title: Identifying the outbreak signal of COVID-19 before the response of the traditional disease monitoring system
        date: 2020-10-01
       words: 3331
      flesch: 47
     summary: [18] Timeliness and precision in the detection of infectious disease outbreaks from the information published on the web are crucial for prevention of their spread. Insights from different clinical settings Identification of terms for detecting early signals of emerging infectious disease outbreaks on the web. Computers and Electronics in Agriculture Use of Google Trends to investigate loss-of-smell-related searches during the COVID-19 outbreak Retrospective analysis of the possibility of predicting the COVID-19 outbreak from Internet searches and social media data, China, 2020.
    keywords: china; coronavirus; covid-19; disease; ili; novel; outbreak; sars
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        item: #6952 of 7819
          id: cord-345329-195cqp6s
      author: Heymann, Eric P
       title: How the COVID-19 pandemic illustrated the importance of emergency medicine, and its vital role as a pillar of the healthcare system
        date: 2020-05-23
       words: 818
      flesch: 41
     summary: Faced with an ever increasing number of consults (both COVID-10 and non COVID-19 related cases, the latter a consequence of non-urgent healthcare services having been placed on hold 1 ), EDs were able to rapidly increase their workforce (often relying on retired or ex-ED staff), and completely reorganised the healthcare infrastructure to divide hospitals into 'hot' and 'cold' areas. This has made it abundantly clear that EPs need to be heard and involved in discussions on healthcare policies and funding.
    keywords: healthcare; pandemic
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        item: #6953 of 7819
          id: cord-345338-pf4tsh3v
      author: Shaw, Brian
       title: The lingering manifestations of COVID-19 during and after convalescence: update on long-term pulmonary consequences of coronavirus disease 2019 (COVID-19)
        date: 2020-10-01
       words: 3658
      flesch: 43
     summary: Serial CT features in discharged COVID-19 patients with positive RT-PCR re-test Patient follow-up after discharge after COVID-19 pneumonia: considerations for infectious control Abnormal pulmonary function in COVID-19 patients at time of hospital discharge Post-discharge surveillance and positive virus detection in two medical staff recovered from coronavirus disease 2019 (COVID-19), China Three cases of re-detectable positive SARS-CoV-2 RNA in recovered COVID-19 patients with antibodies Pathological evidence for residual SARS-CoV-2 in pulmonary tissues of a ready-fordischarge patient Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study Evolution of CT findings in patients with mild COVID-19 pneumonia Chest CT findings of COVID-19 pneumonia by duration of symptoms Time course of lung changes on chest CT during recovery from 2019 novel coronavirus (COVID-19) pneumonia CT scans of patients with 2019 novel coronavirus (COVID-19) pneumonia Radiologic findings of coronavirus disease (COVID-19): clinical correlation is recommended Lung fibrosis: an undervalued finding in COVID-19 pathological series Radiology-pathology correlation in recovered COVID-19, demonstrating organizing pneumonia Pneumonia Low-dose CT in COVID-19 outbreak: radiation safety, image wisely, and image gently pledge Radiology-pathology correlation in recovered COVID-19, demonstrating organizing Organizing pneumonia: chest HRCT findings The role of chest imaging in patient management during the COVID-19 pandemic: a multinational consensus statement from the fleischner society Role of chest CT in resource-driven healthcare systems COVID-19) infection: findings and correlation with clinical outcome Coronavirus disease 2019 (COVID-19) diagnostic technologies: a country-based retrospective analysis of screening and containment procedures during the first wave of the pandemic Considerations for postacute rehabilitation for survivors of COVID-19 Coronavirus (COVID-19) The discharge criteria in many of these studies are unclear, and few have reported short-term (1-2 months) follow-ups on COVID-19 patients after hospital discharge.
    keywords: covid-19; days; discharge; findings; patients; pneumonia; studies
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        item: #6954 of 7819
          id: cord-345342-04tvuj9f
      author: Kumar, Rebecca N.
       title: COVID‐19 in an HIV‐positive Kidney Transplant Recipient
        date: 2020-05-26
       words: 1452
      flesch: 42
     summary: Unlike the case series from Spain where HIV patients with COVID-19 changed regimens to include a boosted protease inhibitor, no modifications were made to our patient's ART regimen 6 . We also present a review of COVID‐19 cases in kidney transplant recipients.
    keywords: covid-19; hiv; kidney; patient; transplant
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        item: #6955 of 7819
          id: cord-345356-gn1iwis0
      author: Glebov, Oleg O.
       title: Understanding SARS‐CoV‐2 endocytosis for COVID‐19 drug repurposing
        date: 2020-06-02
       words: 3507
      flesch: 28
     summary: Taken together, the above evidence suggests that SARS-CoV-2 may employ distinct endocytic pathways for cell entry in the upper and lower respiratory tract (Fig. 1) . The Authors Excitement around hydroxychloroquine for treating COVID-19 causes challenges for rheumatology Chloroquine diphosphate in two different dosages as adjunctive therapy of hospitalized patients with severe respiratory syndrome in the context of coronavirus (SARS-CoV-2) infection: preliminary safety results of a randomized, double-blinded Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses Some selective serotonin reuptake inhibitors inhibit
    keywords: cell; covid-19; drugs; endocytosis; entry; human; infection; pathways; sars
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        item: #6956 of 7819
          id: cord-345358-b9u1l3sz
      author: Jacobs, Jeffrey
       title: Case Report of a SARS-CoV-2 Infection in a Patient With Ulcerative Colitis on Tofacitinib
        date: 2020-04-28
       words: 741
      flesch: 43
     summary: Though the risk of infection is thought to be similar to that of non-IBD patients, it remains unknown whether patients with IBD may have a more severe presentation compared with non-IBD patients. The case presented here illustrates that in a relatively healthy individual, tofacitinib may not need to be held in patients with COVID-19 without severe disease.
    keywords: covid-19; patients
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        item: #6957 of 7819
          id: cord-345360-wlzgq7f9
      author: Yan, Alice F.
       title: Perceived Risk, Behavior Changes and Health-related Outcomes During COVID-19 Pandemic: Findings among Adults with and without Diabetes in China
        date: 2020-07-22
       words: 3902
      flesch: 48
     summary: So far, it is unknown how Chinese diabetes patients perceived COVID-19 related risks and how they modified their health-related behaviors accordingly during the pandemic. To our knowledge, this study is the first sizeable nationwide survey to examine Chinese diabetics and healthy non-diabetic residents' attitudes towards COVID-19 risks and the impact of COVID-19 on health-related behavior changes, and self-related health during the home quarantine period in China.
    keywords: china; covid-19; diabetes; health; pandemic; people; risk; smoking; study
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        item: #6958 of 7819
          id: cord-345371-pjbviagq
      author: Lisi, Lucia
       title: Approaching Coronavirus Disease 2019: mechanisms of action of repurposed drugs with potential activity against SARS-CoV-2
        date: 2020-07-23
       words: 10674
      flesch: 18
     summary: Among them, the international Solidarity trial launched by the WHO on March 2020 with the aim to find an effective treatment for COVID-19 patients by comparing four different treatments (i.e., lopinavir/ritonavir, lopinavir/ritonavir plus interferon-β, chloroquine/hydroxychloroquine or remdesivir) against standard of care (see also sections 2 and 3). Besides exerting potential direct antiviral effects, baricitinib might prevent the dysregulated production of pro-inflammatory cytokines typically observed in COVID-19 patients via the inactivation of interleukin-6 (IL6)-JAK-signal transducer and activator of transcription (STAT) pathway (this activity will be more deeply discussed in section 3, especially regarding the JAK inhibitor ruxolitinib).
    keywords: acute; cells; coronavirus; cov-2; covid-19; covid-19 patients; disease; hydroxychloroquine; infection; interferon; patients; pneumonia; protein; remdesivir; ritonavir; rna; sars; study; syndrome; tocilizumab; treatment; use
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        item: #6959 of 7819
          id: cord-345373-ulsz1d85
      author: Grabia, Monika
       title: The Nutritional and Health Effects of the COVID-19 Pandemic on Patients with Diabetes Mellitus
        date: 2020-09-30
       words: 6946
      flesch: 49
     summary: At the time the survey was conducted, stress levels were starting to return to pre-pandemic levels. Study results revealed several improvements in dietary habits of the youngest respondents during the pandemic (see Supplementary Table S10 ).
    keywords: consumption; covid-19; covid-19 pandemic; diabetes; meals; pandemic; respondents; study; table
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        item: #6960 of 7819
          id: cord-345381-9cckppk2
      author: Klimek, Ludger
       title: Use of biologicals in allergic and type-2 inflammatory diseases during the current COVID-19 pandemic: Position paper of Ärzteverband Deutscher Allergologen (AeDA)(A), Deutsche Gesellschaft für Allergologie und Klinische Immunologie (DGAKI)(B), Gesellschaft für Pädiatrische Allergologie und Umweltmedizin (GPA)(C), Österreichische Gesellschaft für Allergologie und Immunologie (ÖGAI)(D), Luxemburgische Gesellschaft für Allergologie und Immunologie (LGAI)(E), Österreichische Gesellschaft für Pneumologie (ÖGP)(F) in co-operation with the German, Austrian, and Swiss ARIA groups(G), and the European Academy of Allergy and Clinical Immunology (EAACI)(H)
        date: 2020-09-07
       words: 6158
      flesch: 34
     summary: Epub ahead of print SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan High IL-6/IFN-γ ratio could be associated with severe disease in COVID-19 patients The society for immunotherapy of cancer perspective on regulation of interleukin-6 signaling in COVID-19-related systemic inflammatory response Why judiciously timed anti-IL 6 therapy may be of benefit in severe COVID-19 infection. COVID-19 patients with a history of respiratory disease develop ARDS more frequently (58 vs. 42%; 14 vs. 11 patients; of these, 4 vs. 2 patients with asthma; n = 50) ARDS = acute respiratory distress syndrome.
    keywords: asthma; atopic; biologicals; cells; coronavirus; course; cov-2; covid-19; disease; infection; pandemic; patients; risk; sars; therapy; treatment; type
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        item: #6961 of 7819
          id: cord-345432-nyklmyw0
      author: Dong, Zai-Quan
       title: The social psychological impact of the COVID-19 pandemic on medical staff in China: A cross-sectional study
        date: 2020-06-01
       words: 3579
      flesch: 46
     summary: Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirusinfected pneumonia in Wuhan, China 2019-nCoV outbreak is an emergency of international concern National Health Commission of the People's Republic of China Preparing for the most critically ill patients with COVID-19: the potential role of extracorporeal membrane oxygenation Psychological impact of severe acute respiratory syndrome on health workers in a tertiary hospital Recommended psychological crisis intervention response to the 2019 novel coronavirus pneumonia outbreak in China: a model of West China Hospital Mental health services for older adults in China during the COVID-19 outbreak Screening for Chinese medical staff mental health by SDS and SAS during the outbreak of COVID-19 Factors associated with mental health outcomes among health care workers exposed to coronavirus disease 2019 Mental health and psychosocial problems of medical health workers during the COVID-19 epidemic in China Mental health survey of medical staff in a tertiary infectious disease hospital for COVID-19 The occupational and psychosocial impact of SARS on academic physicians in three affected hospitals The development and validation of Huaxi emotional-distress index (HEI): a Chinese questionnaire for screening depression and anxiety in non-psychiatric clinical settings The psychological impact of quarantine and how to reduce it: rapid review of the evidence Concern over radiation exposure and psychological distress among rescue workers following the Great East Japan Earthquake The psychological impact of the SARS epidemic on hospital employees in China: exposure, risk perception, and altruistic acceptance of risk SARS control and psychological effects of quarantine The psychosocial effects of being quarantined following exposure to SARS: a qualitative study of Toronto health care workers Severe acute respiratory syndrome (SARS) in Hong Kong in 2003: stress and psychological impact among frontline healthcare workers The immediate psychological and occupational impact of the 2003 SARS outbreak in a teaching hospital Mental health care for medical staff in China during the COVID-19 outbreak Supporting the health care workforce during the COVID-19 global epidemic Lessons learned from the 2019-nCoV epidemic on prevention of future infectious diseases Organizational factors and mental health in community volunteers. A higher prevalence of psychological symptoms was found among medical health workers during COVID-19 than in previous pandemics and epidemics
    keywords: covid-19; exposure; health; hei; outbreak; staff; workers
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        item: #6962 of 7819
          id: cord-345444-j2hgzrtm
      author: Magoon, Rohan
       title: Compounded research challenges amid the COVID-19 pandemic
        date: 2020-09-16
       words: 1044
      flesch: 20
     summary: COVID-19 impact on research, lessons learned from COVID-19 research, implications for pediatric research PROWESS-SHOCK Study Group: Drotrecogin alfa (activated) in adults with septic shock Implications of Practice Variability: Comment Precision Cardiac Anesthesia: key: cord-345444-j2hgzrtm authors: Magoon, Rohan; Ohri, Ruchi title: Compounded research challenges amid the COVID-19 pandemic date: 2020-09-16 journal: Anaesth Crit Care Pain Med DOI: 10.1016/j.accpm.2020.09.002 sha: doc_id: 345444 cord_uid: j2hgzrtm nan highest-priority societal goal of mitigating the morbidity and mortality associated with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
    keywords: covid-19; misinformation; pandemic; research
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        item: #6963 of 7819
          id: cord-345464-9cnbco2i
      author: Kwiatkowski, S.
       title: Why we should not stop giving aspirin to pregnant women during the COVID‐19 pandemic
        date: 2020-06-01
       words: 904
      flesch: 45
     summary: To our knowledge, there is insufficient data to suggest an increased risk between prophylactic use of low-dose aspirin and progression of COVID-19 infection in pregnant women at risk of placental complications. Similar observations have also been made in a small group of young people taking ibuprofen for COVID-19 symptoms 3, 4 .
    keywords: aspirin; covid-19; women
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        item: #6964 of 7819
          id: cord-345466-sjryzsqh
      author: Meng, Xianchun
       title: Chest Imaging Tests versus RT-PCR Testing for COVID-19 Pneumonia: There Is No Best, Only a Better Fit
        date: 2020-10-20
       words: 485
      flesch: 39
     summary: Especially in the application of COVID-19 detection, the widely used throat swabs are affected by many factors that limit detection rates, including the immune status of the body, the specificity of the pathogen target organs, and the disease progression. Those articles studied chest imaging tests (radiography and/or CT) versus reversetranscription polymerase chain reaction (RT-PCR) testing to identify coronavirus disease 2019 (COVID-19).
    keywords: chest; covid-19
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        item: #6965 of 7819
          id: cord-345476-k8r14wi1
      author: Hariyanto, Timotius Ivan
       title: Thyroid disease is associated with severe coronavirus disease 2019 (COVID-19) infection
        date: 2020-07-29
       words: 859
      flesch: 40
     summary: Forest plot that demonstrates the association of thyroid disease with severe COVID-19 disease Physicians should be engaged in close monitoring of thyroid disease patients with suspected COVID-19, for timely detecting signs of disease progression.
    keywords: covid-19; disease; thyroid
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        item: #6966 of 7819
          id: cord-345480-w5zxzpj7
      author: SHI, C.
       title: Clinical observations of low molecular weight heparin in relieving inflammation in COVID-19 patients: A retrospective cohort study
        date: 2020-04-01
       words: 3749
      flesch: 46
     summary: (C1: control group, indices at admission; C2: control group, indices at discharge; C3: control group, changes in indices during hospitalization; H1: heparin group, indices before LMWH treatment; H2: heparin group, indices after LMWH treatment; H3: heparin group, changes in indices before and after LMWH treatment.) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. (C1: control group, indices at admission; C2: control group, indices at discharge; C3: control group, changes in indices during hospitalization; H1: heparin group, indices before LMWH treatment; H2: heparin group, indices after LMWH treatment; H3: heparin group, changes in indices before and after LMWH treatment.) .
    keywords: group; heparin; license; lmwh; patients; preprint; treatment
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        item: #6967 of 7819
          id: cord-345510-togrmvlk
      author: Kinney, Brad
       title: Rapid outdoor non-compression intubation (RONCI) of cardiac arrests to mitigate COVID-19 exposure to emergency department staff
        date: 2020-05-27
       words: 1232
      flesch: 34
     summary: We propose a novel technique for rapid outdoor non-compression intubation (RONCI) of cardiac arrest patients while en route from the ambulance bay to the resuscitation bay to further decrease the risk of viral aerosolization. 3, 4 This has prompted many to question the standard resuscitation of COVID-19 infected cardiac arrest patients, so modification of current resuscitation practices is being explored on many different levels.
    keywords: covid-19; intubation; resuscitation; staff
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        item: #6968 of 7819
          id: cord-345528-rk16pt0i
      author: Yasar, Y.
       title: MantisCOVID: Rapid X-Ray Chest Radiograph and Mortality Rate Evaluation With Artificial Intelligence For COVID-19
        date: 2020-05-08
       words: 3174
      flesch: 53
     summary: From top to bottom, original CXR PA images, annotated images via experts, AI examination results respectively Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults Frequency and distribution of chest radiographic findings in COVID-19 positive patients. The first model is generated to classify whether the input image is x-ray image or not.
    keywords: covid-19; cxr; mortality; patients; rate; ray
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        item: #6969 of 7819
          id: cord-345557-680k32a6
      author: Norbash, Alexander M.
       title: Early-Stage Radiology Volume Effects and Considerations with the COVID-19 Pandemic; Adaptations, Risks, and Lessons Learned
        date: 2020-07-09
       words: 3599
      flesch: 49
     summary: -70% -48% -98% -69% -47% -64% -65% -33% -47% -49% -59% -62% -52% -98% -71% -79% -56% -98% -74% -53% -74% -73% -39 -70% -36%
    keywords: amss; drops; imaging; pandemic; radiology; surge; volume; week
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        item: #6970 of 7819
          id: cord-345610-rx1zmajl
      author: Boggs, Steven D.
       title: Calculate the COVID-19 Equation With the People’s Energy as Key Variable
        date: 2020-04-22
       words: 448
      flesch: 51
     summary: Sophisticated simulations presented in their article guide optimal staffing in intensive care units. key: cord-345610-rx1zmajl authors: Boggs, Steven D. title: Calculate the COVID-19 Equation With the People’s Energy as Key Variable date: 2020-04-22 journal: Anesth Analg DOI: 10.1213/ane.0000000000004892 sha: doc_id: 345610 cord_uid: rx1zmajl nan To the Editor M ascha et al 1 have made a very valuable contribution for those of us trying to determine optimal ICU staffing systems as a consequence of the Coronavirus disease 2019 (COVID-19) pandemic.
    keywords: people; staffing
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        item: #6971 of 7819
          id: cord-345611-xv62h83a
      author: Cavalcanti, A. B.
       title: Hydroxychloroquine alone or in combination with azithromycin to prevent major clinical events in hospitalised patients with coronavirus infection (COVID-19): rationale and design of a randomised, controlled clinical trial
        date: 2020-05-26
       words: 4292
      flesch: 42
     summary: key: cord-345611-xv62h83a authors: Cavalcanti, A. B.; Zampieri, F. G.; Azevedo, L. C.; Rosa, R. G.; Avezum, A.; Veiga, V. C.; Lopes, R. D.; Kawano-Dourado, L.; Damiani, L. P.; Pereira, A. J.; Serpa Neto, A.; Furtado, R.; Tomazini, B.; Bozza, F. A.; Maia, I. S.; Falavigna, M.; Lisboa, T. C.; Fonseca, H.; Machado, F. R.; Berwanger, O.; Investigators, COALITION COVID-19 Brazil I title: Hydroxychloroquine alone or in combination with azithromycin to prevent major clinical events in hospitalised patients with coronavirus infection (COVID-19): rationale and design of a randomised, controlled clinical trial date: 2020-05-26 journal: nan DOI: 10.1101/2020.05.19.20106997 sha: doc_id: 345611 cord_uid: xv62h83a Introduction: Hydroxychloroquine and its combination with azithromycin have been suggested to improve viral clearance in patients with COVID-19, but its effect on clinical outcomes remains uncertain. https://doi.org/10.1101/2020.05.19.20106997 doi: medRxiv preprint Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomised clinical trial Online ahead of print Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19 Association of Treatment With Hydroxychloroquine or Azithromycin With In-Hospital Mortality in P atients With COVID-19 in New York State Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomised Clinical Trial Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Statement: Defining standard protocol items for clinical trials A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 Repeated assessments of results in clinical trials of cancer treatment Design and analysis of randomized clinical trials requiring prolonged observation of each patient.
    keywords: covid-19; days; hydroxychloroquine; license; medrxiv; patients; preprint; protocol; study
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        item: #6972 of 7819
          id: cord-345628-a4c46m2w
      author: Unudurthi, Sathya D.
       title: Cardiac inflammation in COVID-19: Lessons from heart failure
        date: 2020-09-21
       words: 7735
      flesch: 25
     summary: Different types of immune cells play an important role in promoting and regulating cardiac inflammation, and timing as well as identity of inflammatory cell infiltration in heart may vary, depending on the stimulus Inflammation Mechanisms Underlying Ischemic Cardiac Injury: Cardiac ischemia caused by formation of an occlusive thrombus within the coronary artery leads to myocyte necrosis, triggering intense sterile inflammation and immune cell infiltration in hearts. key: cord-345628-a4c46m2w authors: Unudurthi, Sathya D.; Luthra, Priya; Bose, Rajendran J.C.; McCarthy, Jason; Kontaridis, Maria Irene title: Cardiac inflammation in COVID-19: Lessons from heart failure date: 2020-09-21 journal: Life Sci DOI: 10.1016/j.lfs.2020.118482 sha: doc_id: 345628 cord_uid: a4c46m2w Cardiovascular disease (CVD) is the most common co-morbidity associated with COVID-19 and the fatality rate in COVID-19 patients with CVD is highest compared to other comorbidities, such as hypertension and diabetes.
    keywords: cells; coronavirus; cov-2; covid-19; disease; et al; heart; infection; infiltration; inflammation; injury; ischemic; mechanisms; patients; remodeling; sars
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        item: #6973 of 7819
          id: cord-345632-iha2c5zo
      author: Hamdy, Sherif M
       title: Management Strategies of Patients with Neuromyelitis Optica Spectrum Disorder During the COVID-19 Pandemic Era
        date: 2020-08-17
       words: 3994
      flesch: 25
     summary: Here, however, we examined the evidence of NMOSD disease-modifying therapies (DMTs) use during the present period and highlighted different scenarios including treatment of relapses as well as initiation and maintenance of DMTs in order to optimize care of NMOSD patients in the COVID-19 era. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), identified as the cause of coronavirus disease 2019 , is the third known virus of the coronaviridae family to cause outbreaks of severe acute respiratory syndrome. 13 Tailored recommendations for neurologists managing NMOSD patients are currently needed, especially in the case of patients acquiring COVID-19.
    keywords: covid-19; disease; infection; management; neuromyelitis; nmosd; optica; pandemic; patients; risk; spectrum; treatment
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        item: #6974 of 7819
          id: cord-345637-eg8kuewb
      author: Joob, B.
       title: Lung ultrasound in pregnant women with suspicion of COVID‐19
        date: 2020-07-01
       words: 263
      flesch: 35
     summary: key: cord-345637-eg8kuewb authors: Joob, B.; Wiwanitkit, V. title: Lung ultrasound in pregnant women with suspicion of COVID‐19 date: 2020-07-01 journal: Ultrasound Obstet Gynecol DOI: 10.1002/uog.22091 sha: doc_id: 345637 cord_uid: eg8kuewb nan they believe that their course 'represents one possible model for implementing lung ultrasound education and might be a useful launch-pad for gynecologists and obstetricians involved in the management of pregnant patients with confirmed or suspected COVID-19. ' Yet, the limited availability of data on lung ultrasound findings in COVID-19 is a challenge, particularly as various non-specific forms of lung abnormality are observable in this disease 2 .
    keywords: lung
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        item: #6975 of 7819
          id: cord-345655-fb4vv4my
      author: Islam, M. Z.
       title: Risk factors associated with morbidity and mortality outcomes of COVID-19 patients on the 28th day of the disease course: a retrospective cohort study in Bangladesh
        date: 2020-10-29
       words: 3425
      flesch: 52
     summary: key: cord-345655-fb4vv4my authors: Islam, M. Z.; Riaz, B. K.; Islam, A. N. M. S.; Khanam, F.; Akhter, J.; Choudhury, R.; Farhana, N.; Jahan, N. A.; Uddin, M. J.; Efa, S. S. title: Risk factors associated with morbidity and mortality outcomes of COVID-19 patients on the 28th day of the disease course: a retrospective cohort study in Bangladesh date: 2020-10-29 journal: Epidemiology and infection DOI: 10.1017/s0950268820002630 sha: doc_id: 345655 cord_uid: fb4vv4my Diverse risk factors intercede the outcomes of coronavirus disease 2019 (COVID-19). Therefore, it is irrefutably obligatory to determine the risk factors to avert the aggressive consequences of COVID-19 patients.
    keywords: covid-19; disease; mortality; patients; risk; study
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        item: #6976 of 7819
          id: cord-345674-wkwqlnz2
      author: Kobayashi, Jun
       title: Nitric oxide inhalation as an interventional rescue therapy for COVID-19-induced acute respiratory distress syndrome
        date: 2020-05-20
       words: 859
      flesch: 35
     summary: However, inhaled nitric oxide has not yet been formally evaluated. Given the extent of the COVID-19 pandemic, and the large numbers of hospitalized patients requiring respiratory support, clinical use of inhaled nitric oxide may become an alternate rescue therapy before extracorporeal membrane oxygenation for the management of acute respiratory distress syndrome in patients with COVID-19.
    keywords: covid-19; patients; syndrome
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        item: #6977 of 7819
          id: cord-345680-10phij1x
      author: Terpos, Evangelos
       title: Hematological findings and complications of COVID‐19
        date: 2020-05-23
       words: 2695
      flesch: 32
     summary: A polymorphisms in the promoter region of TNF-alpha gene associate with enhanced apoptosis of lymphocytes in HIV-1 subtype C infected individuals from North India IL-19 induces production of IL-6 and TNF-alpha and results in cell apoptosis through TNF-alpha Increased TNF-alpha-induced apoptosis in lymphocytes from aged humans: changes in TNF-alpha receptor expression and activation of caspases Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility The official French guidelines to protect patients with cancer against SARS-CoV-2 infection Inhibitory effect of tumor cellderived lactic acid on human T cells Clinical characteristics of coronavirus disease 2019 in China Clinical features of patients infected with 2019 novel coronavirus in Wuhan Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore Hematologic parameters in patients with COVID-19 infection Haematological parameters in severe acute respiratory syndrome A major outbreak of severe acute respiratory syndrome in Hong Kong Elevated exhaustion levels and reduced functional diversity of T cells in peripheral blood may predict severe progression in COVID-19 patients Dysregulation of immune response in patients with COVID-19 in Wuhan, China Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State Covid-19 in critically ill patients in the seattle region -case series Clinical characteristics of fatal and recovered cases of coronavirus disease 2019 (COVID-19) in Wuhan, China: a retrospective study Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study Association of cardiac injury with mortality in hospitalized patients with COVID-19 in Wuhan, China. 36 2.2 | The emerging role of biomarkers procalcitonin, ferritin and C-reactive protein in the prognosis Coagulation disorders are relatively frequently encountered among COVID-19 patients, especially among those with severe disease.
    keywords: blood; china; coronavirus; covid-19; disease; lymphocyte; patients
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        item: #6978 of 7819
          id: cord-345681-sj0ypr2c
      author: Parks, Courtney A
       title: Food System Workers are the Unexpected but Under Protected COVID Heroes
        date: 2020-06-25
       words: 2231
      flesch: 39
     summary: key: cord-345681-sj0ypr2c authors: Parks, Courtney A; Nugent, Nadine Budd; Fleischhacker, Sheila E; Yaroch, Amy L title: Food System Workers are the Unexpected but Under Protected COVID Heroes date: 2020-06-25 journal: J Nutr DOI: 10.1093/jn/nxaa173 sha: doc_id: 345681 cord_uid: sj0ypr2c Coronavirus disease 2019 (COVID-19) poses an occupational health risk to food system workers including farmers/producers, grocery store workers, emergency food system staff and volunteers (e.g., food pantry workers), and others. Food system workers are some of the most economically vulnerable populations and are at risk of further financial disparities and contraction of COVID-19 during this pandemic.
    keywords: covid-19; food; health; nutrition; pandemic; system; workers
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        item: #6979 of 7819
          id: cord-345686-zy3sulbi
      author: Kow, Chia Siang
       title: Revascularization strategy in patients with acute ST-elevation myocardial infarction amid COVID-19 pandemic
        date: 2020-08-04
       words: 590
      flesch: 31
     summary: The majority of STEMI patients receiving fibrinolytic therapy would require subsequent PCI at some point during hospitalization as part of a pharmacoinvasive or rescue strategy for failed fibrinolysis or threatened reocclusion and thus fibrinolytic therapy may not reduce resource utilization amid COVID-19 pandemic. Such consensus is important to guide local cardiologists who may encounter COVID-19 patients in their daily practice and also to serve as a reference for countries that are yet to issue their local recommendations on the management of acute coronary syndrome amid COVID-19 pandemic.
    keywords: covid-19; patients
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        item: #6980 of 7819
          id: cord-345708-hlnjzunb
      author: Mahendran, Krishantini
       title: COVID‐19 and Postgraduate Dental Training—A commentary
        date: 2020-09-29
       words: 992
      flesch: 39
     summary: Mouth care matters FAQ for dental specialty trainees during current Covid-19 situation https://madei nheene.hee.nhs.uk/Porta ls/0/FAQ%202%20Den tal%20Cor e%20Tra ining %2023%20Apr il Advancing Dental Care: Education and training review -final report Higher specialist training documents and curricula -Royal College of Surgeons Specialty training curriculum for oral medicine The NHS Long Term Plan Not required. We also reflect on adaptations that may be required if there are any future disruptions to dental postgraduate training in the UK. team working and leadership, (c) clinical safety and quality, and (d) good clinical care.
    keywords: care; dcts; dental; training
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        item: #6981 of 7819
          id: cord-345725-8ijgmbmr
      author: Shang, Jingjing
       title: COVID-19 Preparedness in U.S. Home Healthcare Agencies
        date: 2020-06-04
       words: 1290
      flesch: 52
     summary: More urban HHAs had cared for confirmed and recovered COVID-19 patients than rural HHAs, but urban HHAs had less capacity to test for COVID-19 than rural HHAs (9% vs 21%). 17 More urban HHAs had cared for confirmed and recovered COVID-19 patients than rural HHAs, 18 but urban HHAs had less capacity to test for COVID-19 than rural HHAs (9% vs 21%).
    keywords: covid-19; hhas; home; rural
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        item: #6982 of 7819
          id: cord-345730-bxwsup70
      author: Kočar, Eva
       title: Cholesterol, lipoproteins, and COVID-19: basic concepts and clinical applications
        date: 2020-11-04
       words: 4038
      flesch: 33
     summary: Therefore, it is intriguing to contemplate whether NAFLD patients without treatment are more J o u r n a l P r e -p r o o f susceptible for SARS-CoV-2 infection, or whether statin application may directly affect the entry of SARS-CoV-2 into the host cell by regulating cholesterol cell levels. As lipid lowering drugs, statins might thus significantly reduce the attachment and internalization of SARS-CoV-2 by lowering membrane cholesterol levels (Fig. 1c )
    keywords: cell; cholesterol; cov-2; covid-19; disease; hdl; host; infection; lipid; membrane; sars; virus
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        item: #6983 of 7819
          id: cord-345737-b4r0jyjo
      author: Phillips, Dominique
       title: The invisible workforce during the COVID-19 pandemic: Family carers at the frontline
        date: 2020-05-15
       words: 3437
      flesch: 48
     summary: The letter is written by members of the CAREWELL team, a HRB-funded project that aims to promote health and self-care behaviours among working family carers. We argue that there is much to be learned from the recent work restrictions that could benefit employees, including working family carers, beyond this pandemic.
    keywords: carers; covid-19; family; health; pandemic; working
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        item: #6984 of 7819
          id: cord-345745-t36jbg14
      author: Murashita, Takashi
       title: Commentary: The Era of Great Uncertainty
        date: 2020-06-27
       words: 807
      flesch: 39
     summary: Since each hospital is encouraged to adopt a mechanism by which patients can be screened for COVID-19 infection perioperatively, many centers have started screening all patients undergoing elective surgery. However, in urgent or emergent situations such as type A aortic dissection, acute coronary syndromes, and acute valvular endocarditis, patients may need to be taken to the operating room without being tested for COVID-19 infection.
    keywords: covid-19; patient
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        item: #6985 of 7819
          id: cord-345762-khvcoqti
      author: Scott, Ian A.
       title: COVID‐19 pandemic and the tension between the need to act and the need to know
        date: 2020-08-06
       words: 3441
      flesch: 30
     summary: This author also spoke to the media extolling the virtues of AC in all COVID-19 patients admitted to intensive care and announced that the Mount Sinai hospital system had changed its protocols to begin giving such patients therapeutic doses of AC. Hopefully, the same problems will not occur with remdesivir, whichdespite limited and conflicting evidence of clinical improvement from only two placebo-controlled RCT 19, 20 and one non-controlled cohort study 5has now become a 'standard of care' in the United States for COVID-19 patients with severe pneumonia.
    keywords: adaptive; covid-19; drug; patients; therapies; treatment; trial
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        item: #6986 of 7819
          id: cord-345786-1o9nx7z9
      author: Bernstein, Charles N
       title: Worldwide Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: An International Survey
        date: 2020-08-14
       words: 3739
      flesch: 47
     summary: It is unknown to what extent the responses reflect the majority of gastroenterologists managing IBD patients in each jurisdiction, especially because the respondents were leaders in IBD management in their respective countries. 3) Are you conducting any elective endoscopy in IBD patients, and if so, for which indications have you been undertaking endoscopy ( Bangladesh (n = 2)
    keywords: centers; countries; covid-19; ibd; management; persons; testing
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        item: #6987 of 7819
          id: cord-345809-tevi0sup
      author: Bidmead, Elaine
       title: Covid-19 and the ‘new normal’: are remote video consultations here to stay?
        date: 2020-08-22
       words: 3441
      flesch: 42
     summary: key: cord-345809-tevi0sup authors: Bidmead, Elaine; Marshall, Alison title: Covid-19 and the ‘new normal’: are remote video consultations here to stay? date: 2020-08-22 journal: Br Med Bull DOI: 10.1093/bmb/ldaa025 sha: doc_id: 345809 cord_uid: tevi0sup INTRODUCTION: During the UK Covid-19 lockdown, video consultations (telemedicine) were encouraged.
    keywords: consultations; covid-19; health; staff; technology; telemedicine; use; video
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        item: #6988 of 7819
          id: cord-345834-l2e5v39s
      author: Anacleto, M.A.
       title: Diffusive process under Lifshitz scaling and pandemic scenarios
        date: 2020-08-20
       words: 5230
      flesch: 57
     summary: [10] , and a study to predict COVID-19 peaks around the world based on active cases curves, introduced by Tsallis et al. In our investigation, we introduce a new version of the diffusion equation inspired by Horava's work, and we use it to fit real active cases data of COVID-19 from Germany, Spain and Brazil.
    keywords: cases; covid-19; curves; data; diffusion; model; pandemic
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        item: #6989 of 7819
          id: cord-345841-pq5f82gf
      author: PATBERG, Elizabeth T.
       title: COVID-19 Infection and Placental Histopathology in Women Delivering at Term
        date: 2020-10-19
       words: 5903
      flesch: 37
     summary: 250 For the secondary objective, when comparing asymptomatic COVID-19 patients (n=67) 251 to the controls, a significant difference was again observed in the frequency of fetal vascular 252 malperfusion and villitis of unknown etiology (31.3% (21/67) vs 3.6% (2/56), p<0.0001; and 253 22.4% (15/67) versus 7.1% (4/56), p=0.020, respectively; Table 5 ). Therefore, we undertook this retrospective cohort study to compare 100 placental pathology findings between women with COVID-19 at term versus a control group of 101 between asymptomatic COVID-19 patients and placental pathology.
    keywords: cases; covid-19; etiology; malperfusion; patients; placental; vascular; villitis
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        item: #6990 of 7819
          id: cord-345858-xedkxkz4
      author: Ge, Y.
       title: Effect of different resumption strategies to flatten the potential COVID-19 outbreaks amid society reopens: a modeling study
        date: 2020-06-26
       words: 2286
      flesch: 51
     summary: Therefore, TR imported 75% of exposed cases compared to DR and, to this end, HR combined the 184 above three strategies to grant it the lowest number of imported exposed cases (52.5% of DR . 159 Cumulative cases represented infected subjects including imported exposed cases.
    keywords: cases; epidemic; license; preprint
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        item: #6991 of 7819
          id: cord-345860-d02x3151
      author: Thome, Johannes
       title: The impact of the COVID-19 outbreak on the medico-legal and human rights of psychiatric patients
        date: 2020-05-29
       words: 1742
      flesch: 24
     summary: Considering these value-based principles, practical advices for mental health workers on how to protect and defend the rights of patients with severe mental illness in the circumstances of a pandemic may include: (a) close links being built and maintained with nonmedical professionals (such as those within the legal sector) involved in psychiatric patient care; (b) regular contact with external agents being maintained to ensure that no unilateral decisions are taken without prior consultation with mental health experts, representatives of patients, and their relatives; (c) expert information about the medical (and not just psychiatric) background of patients being communicated to these external agents with a special emphasis on the presence of infectious disease and on possible preventive measures; (d) the use of electronic means of communication being used as a possible route to guaranteeing patients' access to their fundamental rights while simultaneously protecting the health of their legal representatives; and (e) awareness being created for the special needs of vulnerable groups (such as psychiatric patients) by mental health professionals in collaboration with decision-makers in social services and political and legal institutions. We believe that this represents a paradigm shift in psychiatric care and that the consideration of the fundamental rights of psychiatric patients as “less important” than infection control measures compel mental health professionals to “advocate for … patients and their caregivers” in this time of crisis [1].
    keywords: covid-19; health; patients; rights
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        item: #6992 of 7819
          id: cord-345866-wy07gd17
      author: Aghamohammadi, Mehdi
       title: Prophylactic anticoagulant therapy for reducing the risk of stroke and other thrombotic events in COVID-19 patients
        date: 2020-05-11
       words: 628
      flesch: 47
     summary: It was concluded that due to the high number of arterial and especially venous thromboembolic events in hospitalized patients, especially in the first 24 h of admission, as well as the high number of positive VTE cases in imaging, They urgently stated the needs to improve VTE diagnostic strategies and thromboembolic events and also consider thromboprophylaxis in patients with COVID-19. key: cord-345866-wy07gd17 authors: Aghamohammadi, Mehdi; Alizargar, Javad; Hsieh, Nan-Chen; Wu, Shu-Fang Vivienne title: Prophylactic anticoagulant therapy for reducing the risk of stroke and other thrombotic events in COVID-19 patients date: 2020-05-11 journal: J Formos Med Assoc DOI: 10.1016/j.jfma.2020.05.005 sha: doc_id: 345866 cord_uid: wy07gd17 nan Prophylactic anticoagulant therapy for reducing the risk of stroke and other thrombotic events in COVID-19 patients The first confirmed case of COVID-19 in Taiwan 1 had sore throat, dry cough, fatigue and low-grade fever as the first symptoms.
    keywords: covid-19; patients
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        item: #6993 of 7819
          id: cord-345879-nbfg47x5
      author: Bonaz, Bruno
       title: Targeting the cholinergic anti-inflammatory pathway with vagus nerve stimulation in patients with Covid-19?
        date: 2020-07-29
       words: 4079
      flesch: 33
     summary: In fact, upregulation of ACE2 appears to be protective against tissue damage caused by SARS-CoV-2 (see for review Farsalinos et al.) However, active IBD, older age and presence of comorbidities are associated with a higher risk of COVID-19 pneumonia and death in patients with IBD (Bezzio et al. 2020) .
    keywords: covid-19; et al; inflammatory; nerve; patients; vagal; vagus; vns
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        item: #6994 of 7819
          id: cord-345887-ymo4mxx7
      author: Pinky
       title: Mesenchymal Stem Cell Derived Exosomes: a Nano Platform for Therapeutics and Drug Delivery in Combating COVID-19
        date: 2020-07-13
       words: 5723
      flesch: 36
     summary: key: cord-345887-ymo4mxx7 authors: Pinky; Gupta, Suchi; Krishnakumar, Vishnu; Sharma, Yashvi; Dinda, Amit Kumar; Mohanty, Sujata title: Mesenchymal Stem Cell Derived Exosomes: a Nano Platform for Therapeutics and Drug Delivery in Combating COVID-19 date: 2020-07-13 journal: Stem Cell Rev Rep DOI: 10.1007/s12015-020-10002-z sha: doc_id: 345887 cord_uid: ymo4mxx7 The recent pandemic situation transpired due to coronavirus novel strain SARS-CoV-2 has become a global concern. Another application of MSC derived exosomes has been presented in drug delivery, which has made these nano-vesicles an attractive clinical tool.
    keywords: cell; covid-19; delivery; disease; drug; exosomes; lung; mesenchymal; mscs; patients; potential; role; stem; studies
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        item: #6995 of 7819
          id: cord-345908-66lku5c2
      author: Lin, Y.
       title: Ultra-High-Resolution CT Follow-Up in Patients with Imported Early-Stage Coronavirus Disease 2019 (COVID-19) Related Pneumonia
        date: 2020-04-06
       words: 2902
      flesch: 41
     summary: Interestingly, all cases except one showed signs of pneumonia on CT images before achieving positive rRT-PCR results. UHR-CT with maximum matrix size improved the spatial resolution and image quality of CT scans, which was more suitable for the assessment of GGO, intralobular reticulation, and intralesional vessels than conventional chest CT
    keywords: covid-19; follow; license; medrxiv; preprint
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        item: #6996 of 7819
          id: cord-345910-o78scael
      author: Conejero, Ismaël
       title: Épidémie de COVID-19 et prise en charge des conduites suicidaires: challenge et perspectives
        date: 2020-05-08
       words: 4068
      flesch: 44
     summary: La solitude est également liée à un recours accru aux services de santé chez les plus de 60 ans [47] , à un sentiment de déconnexion, une aggravation de troubles cognitifs préexistant et à une forte probabilité de passage à l'acte suicidaire [48] . Une forte association entre J o u r n a l P r e -p r o o f trouble de l'humeur et la présence d'anticorps dirigés contre les virus de la grippe A, de la grippe B et une souche de coronavirus (HCov-NL63) a été retrouvée en comparaison à des sujets contrôles [33] .
    keywords: confinement; covid-19; dans; des; est; health; les; review; risque; suicidaire; suicide; sur; une
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        item: #6997 of 7819
          id: cord-345929-z7yfegr5
      author: Thakur, Suman S.
       title: Proteomics and Its Application in Pandemic Diseases
        date: 2020-11-06
       words: 1360
      flesch: 9
     summary: From Interaction-Based to Ribosomal Biology Impact on Disease and Risk Processes Molecular Basis of SARS-CoV-2 Infection and Rational Design of Potential Antiviral Agents: By using NMR spectroscopy, Loo et al. reported that inactivation by heat causes the degradation of lipoproteins and changes in various metabolic information in SARS-CoV-2-infected plasma samples.
    keywords: covid-19; protein; sars; virus
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        item: #6998 of 7819
          id: cord-345937-ddwzr112
      author: Mishra, Ajay Kumar
       title: Cardiac drugs and outcome in COVID - 19
        date: 2020-04-14
       words: 272
      flesch: 24
     summary: key: cord-345937-ddwzr112 authors: Mishra, Ajay Kumar; Sahu, Kamal Kant; Sargent, Jennifer title: Cardiac drugs and outcome in COVID - 19 date: 2020-04-14 journal: QJM DOI: 10.1093/qjmed/hcaa127 sha: doc_id: 345937 cord_uid: ddwzr112 nan Type: Letter to the editor Title: Cardiac drugs and outcome in COVID -19 We read with much interest the article Are certain drugs associated with enhanced mortality in COVID -19 by Goldstein We agree with the authors that increase expression of ACE 2 receptor potentially increases viral entry and disease severity, however the data regarding only ARB's causing the same might not be enough. (9) Though at present there is not enough evidence of any potential benefit or harm of most prescribed medications including the ARBs, ACEi, Statins, Antiviral agents we strongly agree with the authors that meticulous and detailed reporting of medications of COVID -19 affected patients is crucial in order to further understand the multifaceted interaction of the virus, medications, and clinical outcome.
    keywords: covid
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        item: #6999 of 7819
          id: cord-345973-fb3gkc0f
      author: Thibault, Ronan
       title: Nutrition of the COVID-19 patient in the intensive care unit (ICU): a practical guidance
        date: 2020-07-19
       words: 4847
      flesch: 42
     summary: All over the world, ICU COVID-19 patients are rather similar in terms of vulnerability (older, chronic diseases, low food intake for 5-10 days) To our knowledge, there is no specific indication for arginine in ICU COVID-19 patients.
    keywords: case; covid-19; icu; malnutrition; nutrition; patients; risk; sars; use
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        item: #7000 of 7819
          id: cord-345976-z5gorbwp
      author: Cella, Laura
       title: Injuries From Asymptomatic COVID-19 Disease: New Hidden Toxicity Risk Factors in Thoracic Radiation Therapy
        date: 2020-10-01
       words: 1648
      flesch: 32
     summary: Recent studies, some in the form of case reports, refer to computed tomography (CT) imaging abnormalities, even in recovered asymptomatic COVID-19 patients. The major challenge will especially concern patients with asymptomatic COVID-19.
    keywords: asymptomatic; covid-19; lung; patients; radiation
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        item: #7001 of 7819
          id: cord-345998-701aker9
      author: Tantrakarnapa, Kraichat
       title: Challenging the spread of COVID-19 in Thailand
        date: 2020-10-07
       words: 1929
      flesch: 44
     summary: This paper aimed to present the distribution and pattern of COVID-19 disease and prediction of number cases in Thailand. This analysis shows the evolution of COVID-19 cases in Thailand from the first case until 6 July 2020.
    keywords: cases; covid-19; model; prediction; thailand
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        item: #7002 of 7819
          id: cord-346006-caxx5fbz
      author: van den Oever, Wendy
       title: Risicofactoren voor een ernstig beloop van COVID-19
        date: 2020-09-10
       words: 2015
      flesch: 52
     summary: Meerdere internationale onderzoeken laten zien dat hypertensie een predisponerende factor is voor een ernstiger ziektebeloop van COVID-19. Hypertensie kwam in onze onderzoekspopulatie wel relatief vaak voor bij patiënten met een slechter ziektebeloop, maar was geen onafhankelijke predisponerende factor.
    keywords: als; covid-19; diabetes; een; het; mellitus; niet; van; voor; zijn
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        item: #7003 of 7819
          id: cord-346008-6v2gdz4a
      author: Jeong, Areum
       title: Changes in the Clinical Practice of Ophthalmology during the Coronavirus Disease 2019 (COVID-19) Outbreak: an Experience from Daegu, Korea
        date: 2020-06-02
       words: 1153
      flesch: 48
     summary: Due to close contact during examination, frequent exposure to tears and ocular discharge, and the inevitable sharing of equipment, ophthalmologists and patients are at a higher risk of SARS-CoV-2 infection. Patients with emergency eye conditions are evaluated under infection control team.
    keywords: control; covid-19; patients; sars
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        item: #7004 of 7819
          id: cord-346015-bzeqs5oh
      author: Wang, Yeming
       title: Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial
        date: 2020-04-29
       words: 5241
      flesch: 39
     summary: The median age of study patients was 65 years (IQR 56-71); sex distribution was 89 (56%) men versus 69 (44%) women in the remdesivir group and 51 (65%) versus 27 (35%) in the placebo group (table 1). In patients with use of remdesivir within 10 days after symptom onset, 28-day mortality was not significantly different between the groups, although numerically higher in the placebo group; by contrast, in the group of patients with late use, remdesivir patients had numerically higher 28-day mortality, although there was no significant difference.
    keywords: clinical; covid-19; days; group; patients; placebo; remdesivir; sars; study; time; treatment; trial
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        item: #7005 of 7819
          id: cord-346017-wforwxes
      author: Kasperkiewicz, M.
       title: Expert recommendations for the management of autoimmune bullous diseases during the COVID‐19 pandemic
        date: 2020-04-25
       words: 649
      flesch: 26
     summary: Since immunosuppressive therapy can generally inhibit antiviral immunity, AIBD patients undergoing immunomodulatory treatment, especially elderly patients with co-morbidities, may be at higher risk of worse outcomes should they develop COVID-19. key: cord-346017-wforwxes authors: Kasperkiewicz, M.; Schmidt, E.; Fairley, J.A.; Joly, P.; Payne, A.S.; Yale, M.L.; Zillikens, D.; Woodley, D.T. title: Expert recommendations for the management of autoimmune bullous diseases during the COVID‐19 pandemic date: 2020-04-25 journal: J Eur Acad Dermatol Venereol DOI: 10.1111/jdv.16525 sha: doc_id: 346017 cord_uid: wforwxes Autoimmune bullous diseases (AIBDs) are potentially life‐threatening disorders comprising intra‐epidermal/epithelial (pemphigus) and sub‐epidermal/epithelial blistering diseases (pemphigoid and dermatitis herpetiformis).
    keywords: covid-19; patients; treatment
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        item: #7006 of 7819
          id: cord-346019-nxn4sfzw
      author: Morollón, Noemí
       title: Tratamientos habituales utilizados en cefaleas y neuralgias y sars-cov-2.posicionamiento del grupo de estudio de cefaleas de la sociedad española de neurología
        date: 2020-07-28
       words: 1779
      flesch: 33
     summary: No obstante, nos parece recomendable no indicarlos de novo como tratamiento preventivo de la migraña durante la pandemia COVID-19, pues hay Indicado en el tratamiento del ataque agudo de dolor de intensidad moderada de migraña con nivel de evidencia Es conocido el efecto inmunodepresor de los corticoides, por lo que recomendamos evitar su indicación oral habitual de 1 mg/kg en pacientes con cefalea en racimos durante la pandemia y extender el uso de los bloqueos de los nervios occipitales 4 Los corticoides también se usan por vía parenteral u oral en el estado migrañoso en urgencias 4 , pero son pautas muy cortas por lo que no están desaconsejados, salvo en pacientes con alta sospecha o diagnóstico de COVID-19 grave (Tabla 1), en los que se recomienda evitar su uso.
    keywords: angiotensina; como; con; covid-19; del; los; pacientes; por; que; tratamiento
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        item: #7007 of 7819
          id: cord-346024-7e6px71s
      author: Das, Dipayan
       title: Truncated inception net: COVID-19 outbreak screening using chest X-rays
        date: 2020-06-25
       words: 4830
      flesch: 49
     summary: Authors in [19, 20] have proposed deep learning models to classify COVID-19 positive CXRs from normal and Pneumonia cases, respectively. Such a varied dataset combinations for analyzing deep learning models on COVID-19 CXRs has not been demonstrated in the literature so far.
    keywords: cases; covid-19; cxrs; data; inception; learning; model; net; pneumonia
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        item: #7008 of 7819
          id: cord-346026-l9cyzocv
      author: Aneja, Ranjan
       title: An assessment of socioeconomic impact of COVID‐19 pandemic in India
        date: 2020-10-15
       words: 4141
      flesch: 51
     summary: An economic query Emerging outbreaks and epidemic threats: The practicalityand limitations in the development and manufacturing oftreatments for Coronavirus (COVID-19) Consequences of lockdown amid covid-19 pandemic on indian agriculture Banking crisis is impeding India's economy Impact of COVID-19 on Rural Economy in India With Covid-19 crisis dealing sharp blow to struggling financial sector, revival calls for new approach. There are around 40-50 million seasonal migrant workers in India Ongoing research Government of India Ministry of Health and Family Welfare Statistics Division Rural Health The World Bank-IBRD-IDA Ongoing research Finance in the times of coronavirus The psychological impact of quarantine and how to reduce it: A rapid review of the evidence COVID-19 and Macroeconomic Uncertainty: Fiscal and Monetary Policy Response We will never know how many people died of starvation, because no state government will admit to starvation deaths.
    keywords: covid-19; crisis; economy; health; impact; india; lockdown; pandemic; sector
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        item: #7009 of 7819
          id: cord-346037-1sgwy0tx
      author: Le Couteur, David G
       title: COVID-19 Through the Lens of Gerontology
        date: 2020-03-31
       words: 880
      flesch: 47
     summary: Older people in residential aged care facilities and nursing homes have even greater risk of death given their age and comorbidities, confounded by the lack of capacity for social distancing from staff and other residents. There is a widespread perception in the community that the impact of COVID-19 is confined only to older people with underlying illnesses.
    keywords: care; covid-19; people
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        item: #7010 of 7819
          id: cord-346050-ssv1arr1
      author: Hodgkinson, Tarah
       title: Show me a man or a woman alone and I'll show you a saint: Changes in the frequency of criminal incidents during the COVID-19 pandemic
        date: 2020-06-20
       words: 7114
      flesch: 49
     summary: This creates an opportunity to explore the preliminary effects of this lockdown on crime trends in one of Canada's major cities, with the intention of determining if the shift in opportunity structures have changed crime trends and to improve planning for safety and crime prevention for potential further outbreaks of the pandemic and future exceptional events. This research contributes to a growing literature on crime trends and exceptional events, suggesting that addressing the opportunity structures presented by particular exceptional events, the social costs of these events can be reduced.
    keywords: burglary; changes; covid-19; crime; data; events; increase; pandemic; research; routine; theft; time; trends; vancouver
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        item: #7011 of 7819
          id: cord-346062-q0trgj12
      author: Robert, René
       title: Ethical dilemmas due to the Covid-19 pandemic
        date: 2020-06-17
       words: 5719
      flesch: 40
     summary: Indeed, in addition to the elements linked to the lack of available beds, several factors in the decisionmaking process were sources of concern: reduction of the minimum time necessary to make such occasionally life-or-death decisions, decrease due to containment measures in the essential time to be spent with relatives and pressure from the continuous flow of arriving ICU patients. As another application of the societal concept, it has been proposed to prioritize for ICU care the caregivers who have become critically ill, not due to their intrinsic quality or for so as to reward them, but rather for the possibility, once they are cured, of being returning to the operational caregiving circuit
    keywords: beds; care; covid-19; decision; family; health; icu; life; members; pandemic; patients; risk
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        item: #7012 of 7819
          id: cord-346067-zly8p0y7
      author: Ruiz-Irastorza, Guillermo
       title: Second week methyl-prednisolone pulses improve prognosis in patients with severe coronavirus disease 2019 pneumonia: An observational comparative study using routine care data
        date: 2020-09-22
       words: 4555
      flesch: 48
     summary: In the model with mortality as single outcome, week-2-MP patients showed lower mortality (HR 0.24, 95%CI 0.05 to 1.24, p = 0.088), whilst non-pulse glucocorticoid patients had an increased risk of death (HR 2.44, 95%CI 0.88 to 6.76, p = 0.087), both compared with patients with no glucocorticoids. Patients were divided into 4 groups: a) no-glucocorticoids, i.e. patients not receiving glucocorticoids in any form (n = 122); b) non-pulse glucocorticoids, i.e. patients receiving glucocorticoids at doses lower than 100 mg/d for periods longer than 3 days (n = 36, with 10 of them also receiving pulses); c) out-of-week-2-MP, i.e. MP at week 1 or 3, with no additional glucocorticoids at lower doses (n = 30); d) week-2-MP, i.e. patients receiving MP during week 2, with no additional glucocorticoids at lower doses (n = 54).
    keywords: covid-19; disease; glucocorticoids; patients; study; week-2
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        item: #7013 of 7819
          id: cord-346075-q4jbqsh1
      author: Rohith, G.
       title: Dynamics and control of COVID-19 pandemic with nonlinear incidence rates
        date: 2020-06-25
       words: 6137
      flesch: 51
     summary: The control profiles from the sliding mode controller can act as a benchmark while devising COVID-19 control strategies. For α > 0, in the presence of certain level of Governmental control to curb the spread, the incidence rate tends to fall after reaching a peak value.
    keywords: control; covid-19; dynamics; model; number; rate; value
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        item: #7014 of 7819
          id: cord-346087-oa8k5xwc
      author: Chen, Dan
       title: Serum Cystatin C and Coronavirus Disease 2019: A Potential Inflammatory Biomarker in Predicting Critical Illness and Mortality for Adult Patients
        date: 2020-10-08
       words: 3634
      flesch: 36
     summary: Differences in cystatin C levels between groups were determined by the Mann-Whitney U test. Subsequent analysis via the Kaplan-Meier methods revealed that overall COVID-19 patients with a baseline cystatin C level ≥ 1:36 mg/L had significantly worse outcomes, compared to those with cystatin C levels <
    keywords: covid-19; cystatin; disease; illness; levels; patients; serum; table
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        item: #7015 of 7819
          id: cord-346100-j105jmmg
      author: Zehra, Syeda Sakina
       title: An Insight into Weighing the Impact of Draconian Measures in the Battle Against COVID-19 [Letter]
        date: 2020-08-20
       words: 398
      flesch: 47
     summary: In conclusion, we agree that draconian measures have benefitted nations against COVID-19, but on the other side of the coin, it has come at a price. Dove Medical Press encourages responsible, free and frank academic debate.
    keywords: journal
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        item: #7016 of 7819
          id: cord-346102-0fwf1m28
      author: Tien, Homer
       title: Critical care transport in the time of COVID-19
        date: 2020-05-13
       words: 1827
      flesch: 44
     summary: key: cord-346102-0fwf1m28 authors: Tien, Homer; Sawadsky, Bruce; Lewell, Michael; Peddle, Michael; Durham, Wade title: Critical care transport in the time of COVID-19 date: 2020-05-13 journal: CJEM DOI: 10.1017/cem.2020.400 sha: doc_id: 346102 cord_uid: 0fwf1m28 Critical care transport organizations are nimble, operationally focused institutions that can aid in managing crises. Under the prepandemic staffing matrix, Ornge required that a critical care paramedic be paired with a second critical care (or advanced care flight) paramedic to provide critical care transport.
    keywords: air; care; covid-19; ornge; pandemic; transport
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        item: #7017 of 7819
          id: cord-346105-2f6nj4to
      author: Yang, T.-H.
       title: Systematic Review and Meta-analysis of the Effectiveness and Safety of Hydroxychloroquine in COVID-19.
        date: 2020-05-12
       words: 5440
      flesch: 49
     summary: Among the included trials, two trials which were conducted in China studied hydroxychloroquine effect at a dose of 400 mg when given daily for 5 days In addition, another French trial tested hydroxychloroquine effect when given at a dose of 600 mg daily
    keywords: covid-19; funder; hydroxychloroquine; medrxiv; medrxiv preprint; perpetuity; preprint; review
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        item: #7018 of 7819
          id: cord-346109-fcytebfz
      author: Lie, Jessica J.
       title: Optimizing Resident Wellness During a Pandemic: University of British Columbia's General Surgery Program's COVID-19 Experience
        date: 2020-07-19
       words: 2179
      flesch: 44
     summary: Efficiency in delivering information and patient care minimizes additional stress to residents that is caused by the pandemic. By having a reserve team, prioritizing the safety of residents and taking burnout seriously, the culture of wellness and sense of community in our program are emphasized.
    keywords: health; pandemic; program; residents; wellness
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        item: #7019 of 7819
          id: cord-346115-xilbhy37
      author: Gattinoni, Luciano
       title: COVID-19: scientific reasoning, pragmatism and emotional bias
        date: 2020-10-12
       words: 1107
      flesch: 47
     summary: Another example is provided when Tobin et al. say Patients with acute severe asthma develop large pleural Open Access *Correspondence: gattinoniluciano@gmail.com 1 Yet, it seems to us that most of the arguments, counterarguments, attempts to correct, disparage and set-therecord-straight expressed by Tobin et al.
    keywords: care; covid-19; tobin
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        item: #7020 of 7819
          id: cord-346135-uidvtpjw
      author: Parks, Anna L.
       title: COVID-19 coagulopathy and thrombosis: Analysis of hospital protocols in response to the rapidly evolving pandemic
        date: 2020-09-16
       words: 2188
      flesch: 26
     summary: key: cord-346135-uidvtpjw authors: Parks, Anna L.; Auerbach, Andrew D.; Schnipper, Jeffrey L.; Anstey, James E.; Sterken, David G.; Hecht, Todd E.H.; Fang, Margaret C. title: COVID-19 coagulopathy and thrombosis: Analysis of hospital protocols in response to the rapidly evolving pandemic date: 2020-09-16 journal: Thromb Res DOI: 10.1016/j.thromres.2020.09.018 sha: doc_id: 346135 cord_uid: uidvtpjw As the Coronavirus disease 2019 (COVID-19) pandemic spread to the US, so too did descriptions of an associated coagulopathy and thrombotic complications. Representatives from participating institutions submitted inpatient protocols for incorporation in the analysis between April 10, 2020 and May 5, 2020.
    keywords: covid-19; patients; prophylaxis; protocols; vte
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        item: #7021 of 7819
          id: cord-346146-yal0ctpq
      author: Peyronnet, Violaine
       title: Infection par le SARS-CoV-2 chez les femmes enceintes. Actualisation de l’état des connaissances et de la proposition de prise en charge. CNGOF
        date: 2020-10-05
       words: 9033
      flesch: 52
     summary: Pour le HCSP, ce bilan doit être répété en cas de poursuite de l'hospitalisation à 7-9 jours de l'admission. Pour l'analyse de la littérature, une recherche a été effectuée sur la base de donnée Pubmed en utilisant les mots clés associant « codiv-19 », « Sars-Co-V-2 », « Pregnancy », « congenital infection », « delivery », « maternal outcome ».
    keywords: cas; charge; chez; coronavirus; cov-2; covid-19; dans; des; doit; est; femmes; grossesse; infection; les; par; pas; patients; pendant; peut; pour; pregnancy; prise; que; qui; risque; sars; sont; sur; symptômes; une; été; être
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        item: #7022 of 7819
          id: cord-346160-n9i0blv1
      author: Gogoi, Mayuri
       title: Putting the voices and insights of migrants and diverse ethnic groups at the centre of our response to COVID-19
        date: 2020-10-10
       words: 1349
      flesch: 30
     summary: Despite calls to ensure ethnicity is integral to COVID-19 research, opportunities have been missed to engage with individuals from ethnic minority groups, and even more notably, recent migrants. 5 Despite calls to ensure ethnicity is integral to COVID-19 research, 6 opportunities have been missed to engage with these communities, and even more notably, recent migrants.
    keywords: covid-19; groups; migrants; research
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        item: #7023 of 7819
          id: cord-346182-61i4jjys
      author: Myers, Jeffrey L
       title: Frontline Workers in the Backrooms of COVID-19: Caring for the Living and the Dead
        date: 2020-06-17
       words: 4099
      flesch: 45
     summary: Providers already overwhelmed with COVID-19 care found themselves doing unfamiliar work addressing end-of-life needs of patients and families at an unprecedented scale. The COVID-19 pandemic proved a pivotal moment for those who often work in the backrooms of health care to be present at the frontlines working directly with families to first understand and then respond to their unique needs.
    keywords: autopsy; care; covid-19; families; health; medical; michigan; pandemic
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        item: #7024 of 7819
          id: cord-346184-jp3hfbrq
      author: TALEB, S. M.
       title: The first thousands of cases of coronavirus disease 2019 (COVID-19) in Algeria: some risk factors
        date: 2020-08-20
       words: 2451
      flesch: 58
     summary: key: cord-346184-jp3hfbrq authors: TALEB, S. M.; BOUSSAKTA, M. A. title: The first thousands of cases of coronavirus disease 2019 (COVID-19) in Algeria: some risk factors date: 2020-08-20 journal: nan DOI: 10.1101/2020.08.17.20176396 sha: doc_id: 346184 cord_uid: jp3hfbrq Objectives: Providing valuable information on the prevalence of Covid-19 is a crucial step to improve and accentuate the disease surveillance and prevention system as this can limit the spread of the virus. Since February 25, 2020, until May 24, all confirmed patients with coronavirus disease 2019 in Algeria were included in this study.
    keywords: algeria; covid-19; medrxiv; preprint; study
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        item: #7025 of 7819
          id: cord-346185-qmu1mrmx
      author: Velásquez, Ricardo Manuel Arias
       title: Forecast and evaluation of COVID-19 spreading in USA with Reduced-space Gaussian process regression
        date: 2020-05-22
       words: 1125
      flesch: 46
     summary: key: cord-346185-qmu1mrmx authors: Velásquez, Ricardo Manuel Arias; Lara, Jennifer Vanessa Mejia title: Forecast and evaluation of COVID-19 spreading in USA with Reduced-space Gaussian process regression date: 2020-05-22 journal: Chaos Solitons Fractals DOI: 10.1016/j.chaos.2020.109924 sha: doc_id: 346185 cord_uid: qmu1mrmx In this report, we analyze historical and forecast infections for COVID-19 death based on Reduced-Space Gaussian Process Regression associated to chaotic Dynamical Systems with information obtained in 82 days with continuous learning, day by day, from January 21(th), 2020 to April 12(th). Late on January, USA confirmed the first patient with COVID-19, who had recently traveled to China, however, an evaluation of states in USA have demonstrated a fatality rate in China (4%) is lower than New York (4.56%), but lower than Michigan (5.69%).
    keywords: covid-19; process; usa
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        item: #7026 of 7819
          id: cord-346187-pd65r6cp
      author: Singh, Omvir
       title: Association between climatic variables and COVID-19 pandemic in National Capital Territory of Delhi, India
        date: 2020-10-07
       words: 4931
      flesch: 43
     summary: The association among selected climatic variables and COVID-19 pandemic cases has been demonstrated in Fig. 4 and Table 1 . Bashir et al. (2020) have observed a noteworthy positive correlation of mean and minimum temperature with COVID-19 pandemic cases in New York city of USA.
    keywords: cases; covid-19; et al; humidity; pandemic; study; temperature
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        item: #7027 of 7819
          id: cord-346194-l8svzjp2
      author: Nazir, Mehrab
       title: A Multidimensional Model of Public Health Approaches Against COVID-19
        date: 2020-05-26
       words: 4790
      flesch: 36
     summary: Social media has become an important source to broadcast awareness and information regarding control of infectious disease [3] . According to [4] , social media consists of different applications, including social networking sites, and blogs, that are founded on the scientific and ideological foundation of web 2.0 (for example, Facebook, YouTube, and Twitter) that allow users to make, share content, and participate in different activities.
    keywords: awareness; behavior; covid-19; disease; exchange; health; information; media; outbreak
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        item: #7028 of 7819
          id: cord-346225-dmwrm6jl
      author: Lucaciu, Ondine
       title: Oral healthcare during the COVID-19 pandemic
        date: 2020-05-01
       words: 1096
      flesch: 43
     summary: Emergency dental patients that test positive for SARS-CoV-2 should be referred for emergency care where appropriate Transmission-Based Precautions are available. The emergency dental cases are represented by: Severe pain of pulp origin Pericoronaritis, pain in the third molar region Postoperative osteitis, dry alveolitis Dental fractures causing pain or soft-tissue injuries caused by trauma Luxations, dental avulsions Dental treatments required before general medical procedures Final cementation of crowns, decks if provisional restoration is lost, deteriorated or causes gum irritation Biopsies Other emergencies shall be considered as follows: Extended cavities or damaged restorations causing pain (Temporary restorations are performed)
    keywords: covid-19; dental; emergency; patients
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        item: #7029 of 7819
          id: cord-346241-w076l97s
      author: Zhang, Hua
       title: Dynamic CT assessment of disease change and prognosis of patients with moderate COVID-19 pneumonia
        date: 2020-09-19
       words: 4327
      flesch: 45
     summary: The analyzed clinical data included the following characteristics: age, sex, exposure history, disease course, laboratory results, symptoms, comorbid conditions, and CT score focusing on the characteristics of pulmonary lesions, including (a) lesion size and distribution characteristics, (b) number of lung segments involved, (c) patterns of the lesion including GGO, consolidation, vascular thickening, bronchial wall thickening, crazy-paving pattern, (d) and other signs associated with the lesion (for example, adjacent pleural thickening, pleural effusion, and mediastinal lymphadenopathy). Each patient had a different magnitude of CT scores; however, they share a consistent quadratic pattern in that the total CT score increased initially and then decreased during the course.
    keywords: covid-19; days; patients; pneumonia; score; symptoms; thickening
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        item: #7030 of 7819
          id: cord-346246-2phtdgh4
      author: Mattar, Shaikh Abdul Matin
       title: Subacute thyroiditis associated with COVID-19
        date: 2020-08-25
       words: 2252
      flesch: 42
     summary: 6 7 Given prior described literature by Ohsako et al on genetic aspects of subacute thyroiditis and certain human leucocyte antigens that predispose to subacute thyroiditis in a Japanese study, 8 our case further sheds light onto possible research directions into gender, ethnic and therefore genetic predilection of viral subacute thyroiditis in the different populations demonstrated in reports so far. key: cord-346246-2phtdgh4 authors: Mattar, Shaikh Abdul Matin; Koh, Samuel Ji Quan; Rama Chandran, Suresh; Cherng, Benjamin Pei Zhi title: Subacute thyroiditis associated with COVID-19 date: 2020-08-25 journal: BMJ Case Rep DOI: 10.1136/bcr-2020-237336 sha: doc_id: 346246 cord_uid: 2phtdgh4 We report a case of a hospitalised patient with COVID-19 who developed subacute thyroiditis in association with SARS-COV-2 infection.
    keywords: case; covid-19; neck; pain; sars; tachycardia; thyroiditis
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        item: #7031 of 7819
          id: cord-346247-5jwbg6bc
      author: Awasthi, Amit
       title: Statistical interpretation of environmental influencing parameters on COVID-19 during the lockdown in Delhi, India
        date: 2020-09-25
       words: 3963
      flesch: 48
     summary: Spearman correlation is applied to obtain the interconnection of COVID-19 cases with weather parameters. Additionally, the linear regression technique is used to find the trend of COVID-19 cases with temperature and it is estimated that with an increase in temperature by 1 °C, 30 new COVID-19 cases on daily basis will be expected to observe.
    keywords: cases; covid-19; number; study; temperature; weather
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        item: #7032 of 7819
          id: cord-346248-6wkyar57
      author: de Moura, Diogo Turiani Hourneaux
       title: Diagnostic Characteristics of Serological-Based COVID-19 Testing: A Systematic Review and Meta-Analysis
        date: 2020-08-06
       words: 3900
      flesch: 36
     summary: At this time, it is challenging for the authors to draw firm conclusions regarding the absolute utility of serologic-based testing, beyond the simple need to improve diagnostic testing characteristics. Heterogeneity is generally accepted to be present within diagnostic test accuracy reviews (35) .
    keywords: analysis; covid-19; igg; igm; meta; serologic; studies; testing; tests
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        item: #7033 of 7819
          id: cord-346265-jx4kspen
      author: Tatapudi, Hanisha
       title: Impact assessment of full and partial stay-at-home orders, face mask usage, and contact tracing: An agent-based simulation study of COVID-19 for an urban region
        date: 2020-10-19
       words: 5642
      flesch: 45
     summary: Simulation model tracks hourly movements of each individual (susceptible and infected) every day, and records for each susceptible the number of infected contacts and their identification at each location. Up to 14 days before the first reported case can be used as a potential date for simulation model to begin.
    keywords: cases; contact; covid-19; data; face; infection; model; pandemic; simulation; table
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        item: #7034 of 7819
          id: cord-346268-6oufmmw6
      author: Infante, Maria‐Stefania
       title: COVID‐19 in patients with hematological malignancies: A retrospective case series
        date: 2020-08-04
       words: 667
      flesch: 41
     summary: 11 Consumo y Bienestar Social -Profesionales -Situación actual Coronavirus Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area Clinical characteristics of coronavirus disease 2019 in China Survival study of hospitalised patients with concurrent COVID-19 and haematological malignancies COVID-19 in persons with haematological cancers COVID-19 outcomes in patients with hematologic disease Case fatality rate of cancer patients with COVID-19 in a New York Hospital System Clinical outcome of coronavirus disease 2019 in haemato-oncology patients Poor outcome and prolonged persistence of SARS-CoV-2 RNA in COVID-19 patients with haematological malignancies; King's College Hospital experience COVID-19 illness in native and immunosuppressed states: a clinical-therapeutic staging proposal COVID-19 and the clinical hematology laboratory Assessing the impact of lockdown: fresh challenges for the care of haematology patients in the COVID-19 pandemic The French group described a similar incidence of nosocomial COVID-19 in hematological patients.
    keywords: covid-19; outcome; patients
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        item: #7035 of 7819
          id: cord-346276-1dcp05rd
      author: Bonfá, Eloisa
       title: How COVID-19 is changing rheumatology clinical practice
        date: 2020-11-02
       words: 4812
      flesch: 48
     summary: Patients from the rheumatology unit were transferred to the Orthopaedic Institute, along with patients from almost all specialized clinical wards. Consequently, the ceasing of medication or inappropriate self-management occurred in many patients across the country, resulting in flares of disease in some patients.
    keywords: care; covid-19; disease; face; hospital; pandemic; patients; research; rheumatology
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        item: #7036 of 7819
          id: cord-346281-sma6e891
      author: Maldonado, Valente
       title: Repositioning of pentoxifylline as an immunomodulator and regulator of the renin-angiotensin system in the treatment of COVID-19
        date: 2020-06-09
       words: 5721
      flesch: 27
     summary: At the same time, Ang II is considered to function as a growth factor that regulates cell proliferation/apoptosis and fibrosis, as well as a mediator that attracts inflammatory cells to sites of tissue injury [19] . By contrast, Tregs attenuate the activation, proliferation, and effector functions of a wide range of immune cells for the maintenance of auto-tolerance and immune homeostasis
    keywords: ace2; angiotensin; cells; covid-19; cytokines; immune; levels; lung; patients; pentoxifylline; ptx; sars; treatment
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        item: #7037 of 7819
          id: cord-346288-9to4sdfq
      author: Haimovich, A.
       title: Development and validation of the COVID-19 severity index (CSI): a prognostic tool for early respiratory decompensation
        date: 2020-05-12
       words: 5021
      flesch: 39
     summary: Between March 1, 2020 and April 27, 2020, there were a total of 1,792 admissions for COVID-19 patients. (a) Quick Covid Severity Index (qCSI) (b) Covid Severity Index (CSI) Figure 4 : Calibration of qCSI and CSI on external validation dataset Consistent with clinical observations, we noted a significant rate of progression to critical respiratory illness within the first 24 hours of hospitalization in COVID-19 patients.
    keywords: clinical; cohort; covid-19; data; hours; illness; model; patients; qcsi; study; validation; values
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        item: #7038 of 7819
          id: cord-346310-venpta28
      author: Filgueiras, A.
       title: Factors linked to changes in mental health outcomes among Brazilians in quarantine due to COVID-19
        date: 2020-05-16
       words: 4570
      flesch: 52
     summary: Historically, although 46 researchers from the biomedical sciences dedicated more time and resources in the study of 47 physical health, findings from the last 50 years have slowly captured the interest of scientists 48 from diverse fields to look upon mental health to explain somatic diseases, physical functioning, 49 quality-of-life, well-being and work productivity, (Christensen et al., 1999; Prince et al., 2007; 50 Stults-Kolehmainen, Tuit & Sinha, 2014) . For instance, mental health is associated with 51 disability-adjusted life years (DALYs) and premature mortality (Vigo, Kestel, Pendakur et al., 52 2019) with 17% of DALYs attributable to mental health in Brazil and 22% in the United States.
    keywords: anxiety; covid-19; depression; exercise; health; preprint; quarantine; stress; time
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        item: #7039 of 7819
          id: cord-346325-grt67p73
      author: Reilev, M.
       title: Characteristics and predictors of hospitalization and death in the first 9,519 cases with a positive RT-PCR test for SARS-CoV-2 in Denmark: A nationwide cohort
        date: 2020-05-26
       words: 4664
      flesch: 41
     summary: Among PCR positive cases with 4 or more comorbidities, the ORs for hospitalization was 3.6 and 5.2 for death compared to PCR positive cases without any comorbidities ( Table 2) . We included PCR positive cases with an index date prior to April 30 th , We first assessed the number of SARS-CoV-2 PCR positive cases in Denmark as well as the number of individuals tested PCR negative for SARS-CoV-2.
    keywords: age; cases; comorbidities; cov-2; disease; pcr; preprint; sars
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        item: #7040 of 7819
          id: cord-346329-xwbtftju
      author: Mallow, Peter J.
       title: When Second Best Might Be the Best: Using Hospitalization Data to Monitor the Novel Coronavirus Pandemic
        date: 2020-07-10
       words: 2063
      flesch: 41
     summary: We proposed the use of hospitalizations and hospital utilization data to monitor the spread and severity. As a lagging indicator, COVID-19 hospitalizations would normally be considered a second-best solution to measuring a trend in the infection rate.
    keywords: approach; coronavirus; covid-19; hospital; novel
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        item: #7041 of 7819
          id: cord-346338-kdjgu93q
      author: Spinelli, Maria
       title: Parents' Stress and Children's Psychological Problems in Families Facing the COVID-19 Outbreak in Italy
        date: 2020-07-03
       words: 4491
      flesch: 44
     summary: Methods: Parents of children aged between 2- and 14-years-old completed an online survey reporting their home environment conditions, any relation they had to the pandemic consequences, their difficulties experienced due to the quarantine, their perception of individual and parent-child dyadic stress, and their children's emotional and behavioral problems. Conclusions: Dealing with quarantine is a particularly stressful experience for parents who must balance personal life, work, and raising children, being left alone without other resources.
    keywords: children; covid-19; parents; problems; psychological; quarantine; risk; stress; study
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        item: #7042 of 7819
          id: cord-346345-jc9bq0zu
      author: Smith, Colin M
       title: COVID-19-associated brief psychotic disorder
        date: 2020-08-11
       words: 2612
      flesch: 34
     summary: Although studies investigating the treatment of COVID-19 psychosis have not been undertaken, treatment of secondary psychosis should be geared towards treating the underlying illness while managing psychotic symptoms with antipsychotics and benzodiazepines at the lowest possible dose. Further, one patient had a comorbid panic disorder, which may lead to heightened vulnerability to psychotic illness, and another was experiencing homelessness and was on 120 mg of methadone for opioid use disorder, again confounding the diagnosis of COVID-19 psychosis.
    keywords: case; covid-19; history; patients; psychosis; sars; symptoms
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        item: #7043 of 7819
          id: cord-346346-h09pn9sh
      author: Shaikh, Sana
       title: Management of Acute Kidney Injury in COVID-19
        date: 2020-08-06
       words: 5678
      flesch: 38
     summary: Ann Intensive Care Balanced Crystalloids versus Saline in Noncritically Ill Adults Balanced Crystalloids versus Saline in Critically Ill Adults Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial Intravenous Fluids: Finding the Right Balance Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial Pharmacology of new treatments for hyperkalaemia: patiromer and sodium zirconium cyclosilicate Potassium-Binding Agents for the Clinical Management of Hyperkalemia Clinical Pharmacology in Diuretic Use COVID-19 and the Inpatient Dialysis Unit: Managing Resources during Contingency Planning Pre-Crisis Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-analysis of REFERENCES Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area Acute kidney injury in patients hospitalized with COVID-19 Acute Kidney Injury in Hospitalized Patients with COVID-19. Ann Intensive Care Balanced Crystalloids versus Saline in Noncritically Ill Adults Balanced Crystalloids versus Saline in Critically Ill Adults Effect of a Buffered Crystalloid Solution vs Saline on Acute Kidney Injury Among Patients in the Intensive Care Unit: The SPLIT Randomized Clinical Trial Intravenous Fluids: Finding the Right Balance Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial Pharmacology of new treatments for hyperkalaemia: patiromer and sodium zirconium cyclosilicate Potassium-Binding Agents for the Clinical Management of Hyperkalemia Clinical Pharmacology in Diuretic Use COVID-19 and the Inpatient Dialysis Unit: Managing Resources during Contingency Planning Pre-Crisis Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-analysis of randomised clinical trials Timing of Renal-Replacement Therapy in Patients with Acute Kidney Injury and Sepsis Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group.
    keywords: acute; aki; ckrt; covid-19; dialysis; kidney; krt; patients
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        item: #7044 of 7819
          id: cord-346347-r4ork18p
      author: Borrion, Hervé
       title: Measuring the resilience of criminogenic ecosystems to global disruption: A case-study of COVID-19 in China
        date: 2020-10-14
       words: 7568
      flesch: 44
     summary: A set of indicators and mathematical models are introduced that aim to quantitatively describe changes in crime levels in comparison to what could otherwise be expected, and what might be expected by way of adaptation and subsequent resumption of those patterns. To overcome this violation of assumption we propose indicators that take account of the difference between crime levels under two scenarios: with and without the disrupting event (Eq 5): where, D(n) is the difference between Y F (n) and Y A (n), the forecasted crime (under normal conditions) and actual crime time-series (daily crime counts), and n is the (temporal) index of the time-series.
    keywords: case; covid-19; crime; indicators; metrics; patterns; performance; period; phase; point; public; resilience; time
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        item: #7045 of 7819
          id: cord-346370-jdfsacds
      author: Sergi, Consolato M.
       title: The Facemask in Public and Healthcare Workers– A Need not a Belief
        date: 2020-05-13
       words: 1190
      flesch: 44
     summary: Strict isolation and social distancing measures can flatten the coronavirus infectious curve, and the use of facemask needs to be encouraged and facilitated in crowded places, particularly in hospitals where the 6-feet social distancing cannot be adopted because of physical barriers. While strict isolation and social distancing measures can flatten the infectious curve, the use of facemask needs to be encouraged and facilitated where the 6-feet social distancing cannot be implemented because of physical barriers.
    keywords: covid-19; distancing; measures; pandemic
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        item: #7046 of 7819
          id: cord-346389-gbmnoo84
      author: Callender, Lauren A.
       title: The Impact of Pre-existing Comorbidities and Therapeutic Interventions on COVID-19
        date: 2020-08-11
       words: 10050
      flesch: 29
     summary: Engineering Coronavirus susceptibility to the antiviral remdesivir (GS-5734) is mediated by the viral polymerase and the proofreading exoribonuclease Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial Gilead Announces Results From Phase 3 Trial of Remdesivir in Patients With Moderate COVID-19 Available online at Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus Survival after mesenchymal stromal cell therapy in steroidrefractory acute graft-versus-host disease: systematic review and metaanalysis Transplantation of ACE2-mesenchymal stem cells improves the outcome of patients with COVID-19 pneumonia Extraordinary GUrich single-strand RNA identified from SARS coronavirus contributes an excessive innate immune response Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment Effective treatment of severe COVID-19 patients with tocilizumab Favorable changes of CT findings in a patient with COVID-19 pneumonia after treatment with tocilizumab Tocilizumab, an anti-IL6 receptor antibody, to treat Covid-19-related respiratory failure: a case report Rapid and severe Covid-19 pneumonia with severe acute chest syndrome in a sickle cell patient successfully treated with tocilizumab Dissection of the effects of jak and btk inhibitors on the functionality of healthy and malignant lymphocytes COVID-19: combining antiviral and anti-inflammatory treatments Baricitinib for COVID-19: a suitable treatment? TH17 responses in cytokine storm of COVID-19: an emerging target of JAK2 inhibitor fedratinib Baricitinib restrains the immune dysregulation in COVID-19 patients. Given that comorbidities are associated with high mortality among COVID-19 patients, a better understanding of the biological mechanisms that underpin this risk are needed to enable development of appropriate preventative and therapeutic strategies.
    keywords: cases; cells; china; comorbidities; coronavirus; cov-2; covid-19; covid-19 patients; disease; immune; individuals; infection; patients; risk; sars; study; treatment; use
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        item: #7047 of 7819
          id: cord-346395-vdlk3ck2
      author: Martín-Noguerol, Teodoro
       title: Teleworking beyond teleradiology: managing radiology departments during the COVID-19 outbreak
        date: 2020-09-02
       words: 1397
      flesch: 31
     summary: Teleworking should be extended to the rest of non-medical radiology department areas. Teleworking should be extended to the rest of non-medical radiology department areas whenever possible.
    keywords: covid-19; outbreak; patients; teleradiology; teleworking
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        item: #7048 of 7819
          id: cord-346459-tkt5ldyo
      author: Jie, Li Shao
       title: Risk factors for Coronavirus disease 2019 pneumonia after admission outside Wuhan, China
        date: 2020-11-06
       words: 2475
      flesch: 39
     summary: We explored the risk factors for condition changes in COVID-19 pneumonia patients after admission. Elderly patients are more susceptible to disease changes after COVID-19 pneumonia; COVID-19 pneumonia patients who develop disease changes after admission have higher neutrophil ratios, increased D-dimer levels, chest imaging changes, and glucocorticoid usage.
    keywords: admission; changes; condition; covid-19; disease; patients; pneumonia
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        item: #7049 of 7819
          id: cord-346461-eqyte6ko
      author: Scialpi, Michele
       title: Pneumonia misinterpretation in COVID-19: revisitation and update
        date: 2020-08-28
       words: 507
      flesch: 23
     summary: The clinical and chest CT features associated with severe and critical COVID-19 pneumonia Emerging 2019 novel coronavirus (2019-nCoV) pneumonia Chest CT features of COVID-19 in Rome Temporal changes of CT findings in 90 patients with COVID-19 pneumonia: a longitudinal study Time course of lung changes on chest CT during recovery from The progression of computed tomographic (CT) images in patients with coronavirus disease (COVID-19) pneumonia: the CT progression of COVID-19 pneumonia Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The experience of clinical immunologists from China Comorbidities and multi-organ injuries in the treatment of COVID Post-mortem examination of COVID19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings of lungs and other organs suggesting vascular dysfunction Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19 Autopsy findings and venous thromboembolism in patients with COVID-19: a prospective cohort study Acute pulmonary embolism: Lung histopatologic fetures are mainly related to ADA and/or associated with PE and a conseguent respiratory failure causing death in COVID-19 patients.
    keywords: covid-19; pneumonia
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        item: #7050 of 7819
          id: cord-346483-jc0xklzk
      author: Chen, Jun
       title: Deep learning-based model for detecting 2019 novel coronavirus pneumonia on high-resolution computed tomography
        date: 2020-11-05
       words: 3729
      flesch: 44
     summary: Here, we enrolled this technique in identification of COVID-19 pneumonia in CT images. After enrolling artificial intelligence in identifying COVID-19 pneumonia in CT images, the efficiency of diagnosis is greatly improved.
    keywords: covid-19; diagnosis; images; model; patients; pneumonia; radiologists
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        item: #7051 of 7819
          id: cord-346496-crhv0gnt
      author: Sun, Ying
       title: Characteristics and prognostic factors of disease severity in patients with COVID-19: The Beijing experience
        date: 2020-04-24
       words: 3407
      flesch: 45
     summary: Histological characteristics in the lung of COVID-19 patients showed diffuse alveolar damage and interstitial lymphocytes infiltrates [11] . key: cord-346496-crhv0gnt authors: Sun, Ying; Dong, Yanli; Wang, Lifeng; Xie, Huan; Li, Baosen; Chang, Christopher; Wang, Fu-sheng title: Characteristics and prognostic factors of disease severity in patients with COVID-19:
    keywords: covid-19; disease; ferritin; groups; levels; lymphocyte; patients; severity
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        item: #7052 of 7819
          id: cord-346497-q34w8ewl
      author: Liu, Fang-Yan
       title: Evaluation of the Risk Prediction Tools for Patients With Coronavirus Disease 2019 in Wuhan, China: A Single-Centered, Retrospective, Observational Study
        date: 2020-08-25
       words: 3948
      flesch: 42
     summary: key: cord-346497-q34w8ewl authors: Liu, Fang-Yan; Sun, Xue-Lian; Zhang, Yong; Ge, Lin; Wang, Jing; Liang, Xiao; Li, Jun-Fen; Wang, Chang-Liang; Xing, Zheng-Tao; Chhetri, Jagadish K.; Sun, Peng; Chan, Piu title: Evaluation of the Risk Prediction Tools for Patients With Coronavirus Disease 2019 in Wuhan, China: A Single-Centered, Retrospective, Observational Study date: 2020-08-25 journal: Crit Care Med DOI: 10.1097/ccm.0000000000004549 sha: doc_id: 346497 cord_uid: q34w8ewl OBJECTIVES: To evaluate and compare the efficacy of National Early Warning Score, National Early Warning Score 2, Rapid Emergency Medicine Score, Confusion, Respiratory rate, Blood pressure, Age 65 score, and quick Sepsis-related Organ Failure Assessment on predicting in-hospital death in patients with coronavirus disease 2019. Our study is an attempt to identify the best easy-to-use risk prediction tool to be used as an aid to clinical assessment in a simple clinical setting for the management of COVID-19 patients in a triage situation.
    keywords: covid-19; death; hospital; news; oxygen; patients; score; study
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        item: #7053 of 7819
          id: cord-346501-6e91kt6c
      author: Pitt, Michael B
       title: Novel Educational Responses to COVID-19: What is Here to Stay?
        date: 2020-06-06
       words: 970
      flesch: 29
     summary: Our recent call for educational innovations resulted in 172 submitted manuscripts from 82 institutions, in four countries (97% from the United States). 11 COVID-19 presented unprecedented challenges, requiring educational innovations to ensure trainees continue to learn to provide high-quality, evidence-based care, advocate for patients and populations, and maintain wellness.
    keywords: covid-19; pandemic; students; telehealth
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        item: #7054 of 7819
          id: cord-346508-voe8zi2r
      author: Freudenberg, Lutz S.
       title: Global Impact of COVID-19 on Nuclear Medicine Departments: An International Survey in April 2020
        date: 2020-09-17
       words: 3323
      flesch: 36
     summary: Countries that were in the postpeak phase of the pandemic when they responded to the survey, such as South Korea and Singapore, reported a less pronounced impact on nuclear medicine services; however, the overall results of the survey showed that nuclear medicine services worldwide had been significantly impacted. Reduced staff availability due to infection, and reluctance of patients to visit clinics out of concern of risking exposure to infection, may contribute to the observed COVID-19 impact on nuclear medicine services across the world.
    keywords: countries; covid-19; impact; medicine; pandemic; services; survey
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        item: #7055 of 7819
          id: cord-346512-y5d8q5b9
      author: Pellicciaro, Marco
       title: Breast cancer patients with hormone neoadjuvant bridging therapy due to asymptomatic Corona virus infection. Case report, clinical and histopathologic findings
        date: 2020-10-08
       words: 2057
      flesch: 41
     summary: key: cord-346512-y5d8q5b9 authors: Pellicciaro, Marco; Granai, Alessandra Vittoria; Marchese, Gloria; Materazzo, Marco; Cotesta, Maria; Santori, Francesca; Giacobbi, Erica; Servadei, Francesca; Grelli, Sandro; Perretta, Tommaso; Meucci, Rosaria; Pistolese, Chiara Adriana; Vanni, Gianluca title: Breast cancer patients with hormone neoadjuvant bridging therapy due to asymptomatic Corona virus infection. COVID-19 outbreak determined the publication of temporary recommendation leading to an extensive use of neoadjuvant chemotherapy in breast cancer patients.
    keywords: breast; cancer; case; covid-19; patients; surgery
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        item: #7056 of 7819
          id: cord-346539-kxnrf5g5
      author: Riggioni, Carmen
       title: A compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2
        date: 2020-06-14
       words: 15806
      flesch: 41
     summary: All rights reserved hypersensitivity reactions to drugs may occur more often during the pandemic due to the increased use of drugs and drug interactions, which can result in morbilliform rash, erythroderma, Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia Effect of changing case definitions for COVID-19 on the epidemic curve and transmission parameters in mainland China: a modelling study Presumed Asymptomatic Carrier Transmission of COVID-19 Eleven faces of coronavirus disease 2019 The proximal origin of SARS-CoV-2 Phylogenetic network analysis of SARS-CoV-2 genomes Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2 SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Distribution of ACE2, CD147, cyclophilins, CD26 and other SARS-CoV-2 associated molecules in various human tissues and immune cells in health and disease SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses Distribution of ACE2, CD147, CD26 and other SARS-CoV-2 associated molecules in tissues and immune cells in health and in asthma, COPD, obesity, hypertension, and COVID-19 risk factors TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes The potential danger of suboptimal antibody responses in COVID-19 Resistance to coronavirus infection in amino peptidase N-deficient pigs Mammalian Glutamyl Aminopeptidase Genes (ENPEP) and Proteins: Comparative Studies of a Major Contributor to Arterial Hypertension Emerging WuHan (COVID-19) coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26 ACE1 polymorphism and progression of SARS Longitudinal profile of antibodies against SARS-coronavirus in SARS patients and their clinical significance Antibody responses to SARS-CoV-2 in patients with COVID-19 Long-term coexistence of SARS-CoV-2 with antibody response in COVID-19 patients Distinct features of SARS-CoV-2-specific IgA response in COVID-19 patients The Multifaceted B Cell Response in Allergen Immunotherapy COVID-19 Autopsies EAACI position paper on how to classify cutaneous manifestations of drug hypersensitivity Lung eosinophils-A novel virus sink that is defective in asthma? On the other hand, a retrospective study on SARS patients in Hong Kong suggested a better survival rate in patients treated with prednisolone for milder pneumonia or methylprednisolone in more severe cases.
    keywords: ace2; article; asthma; cases; cells; children; copyright; coronavirus; cov-2; covid-19; covid-19 patients; data; days; disease; figure; human; infection; non; pandemic; patients; reserved; responses; rights; risk; sars; studies; study; transmission; treatment; use
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        item: #7057 of 7819
          id: cord-346558-u1e0kzmm
      author: Cattaruzza, Maria Sofia
       title: Tobacco smoking and COVID-19 pandemic: old and new issues. A summary of the evidence from the scientific literature
        date: 2020-05-11
       words: 3537
      flesch: 39
     summary: A meta-analysis based on 15 studies and recently published in pre-print (i.e., without having received a peer-review), showed that 63% of COVID-19 patients with COPD had a severe form of the disease compared to 33% among patients without COPD; the relative risk (RR) was 1.9 (95% CI: 1.4-2.4). The hypothesis that nicotine may have a protective role in COVID-19 patients, has also contributed to the debate on the angiotensin-converting enzyme 2 (ACE2).
    keywords: covid-19; disease; patients; prevalence; smokers; smoking; studies; tobacco
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        item: #7058 of 7819
          id: cord-346560-jir00627
      author: ELGhamrawy, S. M.
       title: Diagnosis and Prediction Model for COVID19 Patients Response to Treatment based on Convolutional Neural Networks and Whale Optimization Algorithm Using CT Images
        date: 2020-04-21
       words: 6340
      flesch: 54
     summary: The DM model, uses Convolutional Neural Networks (CNNs) as a Deep learning technique for segmentation, can process hundreds of CT images in seconds to speed up diagnosis of COVID19 and contribute in its containment. The experimental results show promising performance for the proposed diagnosing and prediction modules, using a dataset with hundreds of real data and CT images. segmentation, can process hundreds of CT images in seconds to speed up diagnosis of COVID-19 and contribute in its containment.
    keywords: aimdp; covid-19; license; medrxiv; model; patient; phase; preprint; treatment
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        item: #7059 of 7819
          id: cord-346565-vsgbmxzv
      author: Cascella, Marco
       title: Rapid and Impressive Response to a Combined Treatment with Single-Dose Tocilizumab and NIV in a Patient with COVID-19 Pneumonia/ARDS
        date: 2020-07-27
       words: 3865
      flesch: 42
     summary: COVID-19 patients may have severe pictures of respiratory failure [13] . COVID-19 patients may have severe pictures of respiratory failure [13] .
    keywords: cards; covid-19; il-6; lung; niv; syndrome; ventilation
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        item: #7060 of 7819
          id: cord-346581-wgvx9usr
      author: Maza-Solano, Juan Manuel
       title: “Estrategias para la práctica de la otorrinolaringología y cirugía de cabeza y cuello durante la fase de control de la COVID-19”
        date: 2020-05-25
       words: 4811
      flesch: 38
     summary: La presencia de anticuerpos en los pacientes COVID-19 debe interpretarse siempre teniendo en cuenta el resultado de la RT-PCR y la fase clínica de la evolución de la enfermedad. La determinación de la presencia del virus debe realizarse mediante RT-PCR ya que su precisión diagnóstica es superior a las pruebas que detectan la presencia de los antígenos de la cápside viral.
    keywords: anticuerpos; cirugía; como; con; coronavirus; cov-2; covid-19; del; desinfección; durante; las; los; mediante; medidas; orl; pacientes; para; pcr; personal; por; presencia; protección; pruebas; que; recomienda; riesgo; sars; una; uso; virus
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        item: #7061 of 7819
          id: cord-346596-uahjsqzh
      author: DOYEN, Denis
       title: Characteristics of cardiac injury in critically ill patients with COVID-19
        date: 2020-10-28
       words: 1671
      flesch: 33
     summary: Electrocardiographic and/or echocardiographic signs of LV abnormalities were the most frequent abnormalities and patients with cardiac injury experienced more RV than LV systolic dysfunction. 58 Electrocardiographic and/or echocardiographic signs of LV abnormalities were the most 59 frequent abnormalities and patients with cardiac injury experienced more RV than LV 60 systolic dysfunction.
    keywords: abnormalities; cardiac; patients
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        item: #7062 of 7819
          id: cord-346606-bsvlr3fk
      author: Siriwardhana, Yushan
       title: The role of 5G for digital healthcare against COVID-19 pandemic: Opportunities and challenges
        date: 2020-11-04
       words: 5231
      flesch: 43
     summary: In contrast to the present 4G networks, 5G supports the creation of new network services as softwarized Network Functions (NFs) by utilizing SDN and NFV technologies. Regime A rapid deployment of new healthcare applications will add extra traffic as well as increase the number of 5G users who access such services.
    keywords: applications; contact; covid-19; data; devices; healthcare; network; patient; services; solutions; technologies; use
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        item: #7063 of 7819
          id: cord-346607-1mewok8l
      author: Oesterle, Tyler S.
       title: Substance Use Disorders and Telehealth in the COVID-19 Pandemic Era: A New Outlook
        date: 2020-10-21
       words: 4952
      flesch: 40
     summary: Many longitudinal outcome studies have allowed researchers to look at which aspects of SUD treatment patient have deemed most helpful to their recovery. A number of studies have shown group based treatment by videoconference, both support groups and treatment groups, including those targeting tobacco, alcohol and opioid use disorders have been shown to provide safe intervention, high patient satisfaction and appear to have similar outcomes to in person treatments.
    keywords: alcohol; care; covid-19; group; health; interventions; patients; sud; telehealth; treatment; use
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        item: #7064 of 7819
          id: cord-346616-kr500kgj
      author: Qian, Song-Zan
       title: Clinical Characteristics and Outcomes of Severe and Critical Patients With 2019 Novel Coronavirus Disease (COVID-19) in Wenzhou: A Retrospective Study
        date: 2020-09-04
       words: 2827
      flesch: 43
     summary: Compared with severe patients, critical patients were older, more likely to exhibit low platelet counts and high blood urea nitrogen, and were in hospital for longer. Compared with severe patients, critical patients were older, more likely to exhibit low platelet counts and high blood urea nitrogen, and were in hospital for longer.
    keywords: acute; clinical; covid-19; injury; patients; study
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        item: #7065 of 7819
          id: cord-346635-rcwrbahh
      author: Park, Kee B.
       title: Global Neurosurgery in the Time of COVID-19
        date: 2020-05-18
       words: 819
      flesch: 46
     summary: There is now an effort within the global surgery community, whose main objective is to increase surgical capacity in the developing world, to advocate for surgical system strengthening as a component of pandemic preparedness strategy in the LMICs. Many neurosurgeons may feel that they have very little to add to the COVID-19 discourse, but in the context of strengthening surgical systems in the developing world, steering some of the funds earmarked for pandemic response and preparedness into surgical capacity building can lead to a more robust neurosurgical delivery system in these countries.
    keywords: capacity; covid-19; pandemic
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        item: #7066 of 7819
          id: cord-346656-5nz0bs4v
      author: Masini, Francesco
       title: Rheumatic disease management in the Campania region of Italy during the COVID-19 pandemic
        date: 2020-07-14
       words: 670
      flesch: 32
     summary: Indeed, the risk of infection in rheumatic patients (i.e., rheumatoid arthritis) is also related to disease activity and a flare due to therapy interruption would confer an increased risk of infection. Usually, discontinuing therapeutic treatment is not recommended, since clinical flares of rheumatic disease develop with subsequent use of other immunosuppressants such as corticosteroids, equally unsafe in the case of COVID-19 occurrence
    keywords: covid-19; patients
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        item: #7067 of 7819
          id: cord-346679-pgynu3s1
      author: Nikogosov, Dimitri A
       title: Comment on “ApoE e4e4 genotype and mortality with COVID-19 in UK Biobank” by Kuo et al.
        date: 2020-08-17
       words: 1147
      flesch: 53
     summary: When applied to the field of genetic association studies, hypothesis-aware approach greatly relaxes the threshold of the significance for detected associations by removing a necessity for an adjustment for multiple testing. APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort ApoE e4e4 genotype and mortality with COVID-19 in UK Biobank Preexisting Comorbidities Predicting COVID-19 and Mortality in the UK Biobank Community Cohort Estimation of significance thresholds for genomewide association scans Estimating Genome-Wide Significance for Whole-Genome Sequencing Studies
    keywords: association; covid-19
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        item: #7068 of 7819
          id: cord-346711-2k736hvr
      author: Shetty, Rohit
       title: Stem cell therapy in COVID-19 – current evidence and future potential
        date: 2020-11-09
       words: 3237
      flesch: 18
     summary: Premises for the Therapeutic Use Mesenchymal Stem Cells Secretome as a prospective therapeutic option for COVID-19 patients The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells Mesenchymal stem cell adhesion to cardiac microvascular 31 endothelium: activators and mechanisms How mesenchymal stem cells interact with tissue immune responses Mechanisms involved in the therapeutic properties of mesenchymal stem cells Crosstalk between mesenchymal stem cells and macrophages in inflammatory bowel disease and associated colorectal cancer Anti-inflammatory and immunomodulatory mechanisms of mesenchymal stem cell transplantation in experimental traumatic brain injury Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells Mesenchymal stem cells in a transgenic mouse model of multiple system atrophy: immunomodulation and neuroprotection Regulators of endothelial and epithelial barrier integrity and function in acute lung injury Therapeutic Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in Acute Lung Injury Mice Anti-inflammatory effects of mesenchymal stem cells: novel concept for future therapies Mesenchymal stem cells 32 improves survival in LPS-induced acute lung injury acting through inhibition of NETs formation Mesenchymal stromal cells improve survival during sepsis in the absence of heme oxygenase-1: the importance of neutrophils Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis Analysis of 4628 cases in the genetic counselling clinic of PUMC Hospital, Proceedings of the Chinese Academy of Medical Sciences and the Peking Union Medical College = Chung-kuo i hsueh k'o hsueh yuan Regulatory T cells in the control of host-microorganism interactions (*) Network analysis of transcriptional responses induced by mesenchymal stem cell treatment of experimental sepsis Mitochondrial transfer from bone-marrow-derived stromal cells to pulmonary alveoli protects against acute lung injury Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS Keratinocyte growth factor increases transalveolar sodium reabsorption in normal and injured rat lungs Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury Platelet-derived growth factor receptor beta identifies mesenchymal stem cells with enhanced engraftment to tissue injury and pro-angiogenic property Prevention of LPSinduced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1 Mesenchymal Stem Cells Overexpressing Angiotensin-Converting Enzyme 2 Rescue Lipopolysaccharide-Induced Lung Injury CXCR4 receptor overexpression in mesenchymal stem cells facilitates treatment of acute lung injury in rats Hepatocyte growth factor gene-modified mesenchymal stem cells reduce radiationinduced lung injury Therapeutic Implications of Human Umbilical Cord Mesenchymal Stromal Cells in Attenuating Influenza A(H5N1) Virus-Associated Acute Lung Injury Intrinsic Immunity Shapes Viral Resistance of Stem Cells Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus IFITM-Family Proteins: The Cell's First Line of Antiviral Defense SARS-CoV-2 Receptor ACE2 Is an Interferon Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues Angiotensin converting enzyme-2 is protective but downregulated in human and experimental lung fibrosis MSCs modified with ACE2 restore endothelial function following LPS challenge by inhibiting the activation of RAS Loss of angiotensin-converting enzyme 2 leads to impaired glucose homeostasis in mice Angiotensin-converting enzyme 2 activity in patients with chronic kidney disease, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association Upregulation of angiotensin-converting enzyme 2 by all-trans retinoic acid in spontaneously hypertensive rats The authors would like to thank Dr K Bhujang Shetty and Dr P Narendra for providing the necessary logistics for this review. Researchers have explored the role of stem cells to suppress the ARDS during the cytokine storm, since mesenchymal stem cells are known to have an immunomodulatory role.
    keywords: acute; cells; covid-19; infection; injury; mesenchymal; patients; sars; stem; therapy; treatment
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        item: #7069 of 7819
          id: cord-346712-ky5gt3pu
      author: Soltan, A. A.
       title: Artificial intelligence driven assessment of routinely collected healthcare data is an effective screening test for COVID-19 in patients presenting to hospital
        date: 2020-07-08
       words: 5771
      flesch: 39
     summary: Basic laboratory blood test data and physiological clinical measurements (vital signs) are amongst routinely collected healthcare data typically available within the first hour of presentation to hospital, and patterns of changes have been described in retrospective, observational studies of COVID-19 patients (variables including lymphocyte count, ALT, CRP, D-Dimer and Bilirubin 3, 4, 16, 17 ) . Five feature sets of clinical variables were investigated (Table 1) including presentation laboratory blood tests, point-of-care blood gas readings, changes in laboratory blood results from pre-admission baseline, vital signs and Charlson Comorbidity Index (CCI).
    keywords: blood; covid-19; data; hospital; license; medrxiv; models; patients; preprint; test
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        item: #7070 of 7819
          id: cord-346721-l6y3n21b
      author: Vega, Marisa
       title: From the Trenches: Inpatient Management of COVID-19 in Pregnancy
        date: 2020-06-15
       words: 1441
      flesch: 37
     summary: but has been noted to be increased in COVID-19 patients, particularly among those requiring 129 admission to the ICU. Obtain ambulatory pulse oximetry measurements (walk test) for stable patients as part of the physical exam -patients may appear deceptively well without exertion • Pocket ultrasounds for biophysical profiles may be useful for COVID-19 patients as an alternative to nonstress tests to limit the number of providers entering the room Step 1: Ask each patient and visitor the following questions.
    keywords: coronavirus; covid-19; disease; management; patients
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        item: #7071 of 7819
          id: cord-346735-52v6pbue
      author: Palchaudhuri, Sonali
       title: Adapting a GI Fellowship to a Pandemic: Novel Approaches to Accommodating a Novel Virus
        date: 2020-04-30
       words: 2332
      flesch: 42
     summary: We included upper-year fellows for tele-calls as a means to decrease burden on first year fellows. Given the fast-paced nature of the pandemic and the multitude of directives from division and hospital leadership, our program aimed to limit anxiety for trainees through the following means: first, we set up daily tele-conferences with all fellows to review all recently-announced policies and directives as well as to address any questions raised by trainees; second, we established a separate weekly meeting with first year fellows in order to address any special needs of the cohort offering most of the clinical inpatient coverage.
    keywords: covid-19; exposure; fellows; hospital; service; year
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        item: #7072 of 7819
          id: cord-346758-pi1hf6xg
      author: Egerup, P.
       title: Impact of SARS-CoV-2 antibodies at delivery in women, partners and newborns
        date: 2020-09-15
       words: 3807
      flesch: 49
     summary: Two additional studies have reported a higher frequency of cesarean delivery of 59% and 93%, respectively, in symptomatic COVID-19 positive women. https://doi.org/10.1101/2020.09.14.20191106 doi: medRxiv preprint A recently published study of 675 parturient women from New York City found a significantly higher frequency of cesarean delivery of 46.7% in symptomatic COVID-19 women as opposed to 45.5% in asymptomatic COVID-19 women and 30.9% in women without COVID-19.
    keywords: antibodies; cov-2; medrxiv; preprint; sars; study; women
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        item: #7073 of 7819
          id: cord-346782-tgaqtnpz
      author: Baldassarre, Emanuele
       title: An andrologist in the front line Covid-19 team
        date: 2020-06-04
       words: 780
      flesch: 51
     summary: You learn to work for 8 h shifts wearing personal protective equipment to know a new job in a short time, to interact with health care workers you barely know or with colleagues who were recruited at the last time, without a specific training or coming from the most different departments. • Ask colleagues from the Covid task force to disseminate procedures and videos on the correct use of personal protective equipment within the group of doctors involved, constantly sending feedback and updates.
    keywords: covid-19; time
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        item: #7074 of 7819
          id: cord-346787-uo8k6qic
      author: Jorgensen, Sarah CJ
       title: Remdesivir: Review of pharmacology, pre‐clinical data and emerging clinical experience for COVID‐19
        date: 2020-05-23
       words: 5492
      flesch: 46
     summary: There are no exclusion criteria related to drug-drug interactions in current remdesivir clinical studies (Table 3) . These reactions tend to be idiosyncratic and uncommon whereas transaminase elevations are consistently observed in a minority of remdesivir treated patients.
    keywords: clinical; cov-2; covid-19; data; days; disease; drug; patients; remdesivir; sars; studies; study
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        item: #7075 of 7819
          id: cord-346791-f2bjsopv
      author: Arslan, Gökmen
       title: Coronavirus Stress, Optimism-Pessimism, Psychological Inflexibility, and Psychological Health: Psychometric Properties of the Coronavirus Stress Measure
        date: 2020-06-04
       words: 5965
      flesch: 25
     summary: Psychological inflexibility was moderately and positively correlated with MPCs (r range = .37-.52), meaning that having a high score on psychological inflexibility is associated with higher scores on MPCs. Comparing self-compassion, mindfulness, and psychological inflexibility as predictors of psychological health Naming the coronavirus disease (COVID-19) and the virus that causes it Using acceptance and commitment therapy to increase self-compassion: a randomized controlled trial Rethinking online mental health services in China during the COVID-19 epidemic Turkish version of Acceptance and Action Questionnaire-II (AAQ-II): A reliability and validity analysis in clinical and non-clinical samples Gratitude and life satisfaction: mediating role of perceived stress Exploring the associations between resilience, dispositional hope, subjective well-being, and psychological health among adults during early stage of COVID-19 Development and initial validation of the coronavirus perceived risk scale and its relationship with mental health Iranian mental health during the COVID-19 epidemic
    keywords: coronavirus; et al; health; inflexibility; optimism; pessimism; problems; stress
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        item: #7076 of 7819
          id: cord-346811-gorp9n1g
      author: Hippisley-Cox, Julia
       title: Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people
        date: 2020-07-31
       words: 5111
      flesch: 45
     summary: key: cord-346811-gorp9n1g authors: Hippisley-Cox, Julia; Young, Duncan; Coupland, Carol; Channon, Keith M; Tan, Pui San; Harrison, David A; Rowan, Kathryn; Aveyard, Paul; Pavord, Ian D; Watkinson, Peter J title: Risk of severe COVID-19 disease with ACE inhibitors and angiotensin receptor blockers: cohort study including 8.3 million people date: 2020-07-31 journal: Heart DOI: 10.1136/heartjnl-2020-317393 sha: doc_id: 346811 cord_uid: gorp9n1g BACKGROUND: There is uncertainty about the associations of angiotensive enzyme (ACE) inhibitor and angiotensin receptor blocker (ARB) drugs with COVID-19 disease. Of 19 486 patients who had COVID-19 disease, 1286 received ICU care.
    keywords: ace; admission; covid-19; disease; icu; inhibitors; patients; risk
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        item: #7077 of 7819
          id: cord-346815-4t4gr0jz
      author: Moshayedi, Pouria
       title: Triage of Acute Ischemic Stroke in Confirmed COVID-19: Large Vessel Occlusion Associated With Coronavirus Infection
        date: 2020-04-21
       words: 1497
      flesch: 36
     summary: However, for acute stroke patients who have a diagnosis of or are under investigation for COVID-19, the concern for nosocomial transmission moderates operational procedures for acute stroke care. We also discuss the current evidence and recommendations to decrease healthcare-associated transmission in acute clinical examination, imaging, and interventional procedures in acute stroke patients with a diagnosis of COVID-19.
    keywords: acute; covid-19; mri; patient; stroke
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        item: #7078 of 7819
          id: cord-346842-ip4i3bdk
      author: Jeon, JuYeun
       title: The Impact of COVID-19 on the Conduct of Clinical Trials for Medical Products in Korea
        date: 2020-09-07
       words: 4169
      flesch: 42
     summary: Kyungpook National University Hospital, located in Daegu, and Seoul Medical Center in Seoul, which operated a professional negative-pressure isolation ward took part in the largest number of COVID-19 clinical trials in Korea, with 4 trials each. The number of clinical trials conducted in Korea continues to increase and an increasing proportion focus on severe and rare incurable diseases.
    keywords: covid-19; guideline; impact; korea; pandemic; study; subjects; trials
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        item: #7079 of 7819
          id: cord-346858-18q8rxzg
      author: Hossain, Md. Tanvir
       title: Social and electronic media exposure and generalized anxiety disorder among people during COVID-19 outbreak in Bangladesh: A preliminary observation
        date: 2020-09-11
       words: 3464
      flesch: 48
     summary: Social Health and Behavior Mental health problems and social media exposure during COVID-19 outbreak Understanding the mental health effects of indirect exposure to mass trauma through the media Understanding depression from psycholinguistic patterns in social media texts2020 We aimed at assessing the prevalence of anxiety among Bangladeshi people during the pandemic in connection with social media exposure (SME) and electronic media exposure (EME).
    keywords: anxiety; covid-19; exposure; health; media; participants; sme
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        item: #7080 of 7819
          id: cord-346866-90w4zepx
      author: Bassareo, Pier Paolo
       title: Learning from the past in the COVID-19 era: rediscovery of quarantine, previous pandemics, origin of hospitals and national healthcare systems, and ethics in medicine
        date: 2020-08-20
       words: 5580
      flesch: 57
     summary: In a catastrophic perspective, since a second outbreak cannot be excluded, we should be ready to cope with it by building new specific COVID-19 hospitals and preparing nurses and general practitioners to face the emergency at the very early beginning, thus preventing patients from the need to be admitted to hospitals. key: cord-346866-90w4zepx authors: Bassareo, Pier Paolo; Melis, Maria Rosaria; Marras, Silvia; Calcaterra, Giuseppe title: Learning from the past in the COVID-19 era: rediscovery of quarantine, previous pandemics, origin of hospitals and national healthcare systems, and ethics in medicine date: 2020-08-20 journal:
    keywords: coronavirus; covid-19; days; death; disease; ethics; health; healthcare; history; hospitals; medical; people; plague; quarantine
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        item: #7081 of 7819
          id: cord-346894-iy35298o
      author: Miranda-Schaeubinger, Monica
       title: A primer for pediatric radiologists on infection control in an era of COVID-19
        date: 2020-07-07
       words: 7277
      flesch: 37
     summary: Standard precautions to minimize the spread of infection within health care facilities from direct contact with contaminations include hand hygiene, use of PPE based on anticipated contact with contaminated material, respiratory hygiene/ cough etiquette, cleaning and disinfection of the environment, and proper handling of patient care equipment and waste [10] . Several studies demonstrated the presence of viral ribonucleic acid (RNA) in 15-53% of stool samples of COVID-19 patients, with persistence of viral RNA in the stool even after respiratory samples became negative.
    keywords: aerosol; care; contact; covid-19; generating; health; infection; patients; ppe; precautions; procedures; protection; radiology; safety; transmission; use
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        item: #7082 of 7819
          id: cord-346917-5dgnj11a
      author: Kuppalli, Krutika
       title: A glimpse into the eye of the COVID-19 cytokine storm
        date: 2020-05-07
       words: 844
      flesch: 39
     summary: These data indicate that cytokine storms may, in concert with suppressed Th1 antiviral adaptive responses, underlie the pathogenesis of severe COVID-19 disease. Longitudinal characteristics of lymphocyte responses and cytokine profiles in the peripheral blood of SARS-CoV-2 infected patients Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology Clinical and immunologic features in severe and moderate coronavirus disease 2019 Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury Interleukin-6 in COVID-19: a Systematic Review and Meta-Analysis Potential factors for prediction of disease severity of COVID-19 patients China National Health Commission.
    keywords: covid-19; disease; patients
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        item: #7083 of 7819
          id: cord-346930-gl573ip9
      author: Hussain, Azhar
       title: Emerging Pharmaceutical Treatments of Novel COVID-19: A Review
        date: 2020-05-24
       words: 4181
      flesch: 43
     summary: Remdesivir is metabolized into its active form, GS-441524, that obscures viral RNA polymerase and evades proofreading by viral exonuclease, causing a decrease in viral RNA production [31] . With the increased risk of anemia at the doses necessary, ribavirin should not be implicated as the first drug of choice in COVID-19 patients.
    keywords: cov-2; covid-19; dose; lopinavir; patients; rna; sars; treatment; virus
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        item: #7084 of 7819
          id: cord-346942-88l03lf0
      author: Kerpel, Ariel
       title: Diagnostic and Prognostic Value of Chest Radiographs for COVID-19 at Presentation
        date: 2020-08-17
       words: 4484
      flesch: 47
     summary: The overall RALE score failed to identify COVID-19 patients at presentation. A high RALE score predicted a poor outcome (intensive care unit hospitalization, intubation, or death) in COVID-19 patients; a score of ≥5 substantially increased the odds of having a poor outcome.
    keywords: chest; covid-19; diagnosis; disease; patients; rale; score; study
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        item: #7085 of 7819
          id: cord-346967-br4kpm6i
      author: Bongiovanni, Marco
       title: Acute hepatitis caused by asymptomatic COVID-19 infection
        date: 2020-09-03
       words: 926
      flesch: 36
     summary: Nevertheless, no data are available on liver enzyme abnormalities in asymptomatic subjects with COVID-19 infection. We report here the case of a young woman diagnosed with COVID-19 infection in absence of respiratory symptoms, presenting at the admission with significant elevation of liver function tests compatible with acute hepatitis.
    keywords: covid-19; infection; liver
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        item: #7086 of 7819
          id: cord-346968-b7g4myed
      author: Barry, Heather E.
       title: Managing medicines in the time of COVID-19: implications for community-dwelling people with dementia
        date: 2020-08-16
       words: 2792
      flesch: 34
     summary: Remote consultation methods using telephone or online services should be utilised by community pharmacists who wish to speak with PwD and their carers about medicines management issues, to conduct medication review or to provide counselling [20, 21] . Medicines management may be adversely affected and deserves careful thought.
    keywords: carers; community; dementia; management; medicines; pwd
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        item: #7087 of 7819
          id: cord-346987-fbqqf00i
      author: Guo, Yongwen
       title: Controls of SARS-CoV-2 transmission in orthodontic practice
        date: 2020-06-05
       words: 4679
      flesch: 38
     summary: Since there may still be asymptomatic patients or patients in the incubation period after resumption of regular activities and a large number of orthodontic patients from a wide spread distribution in need of orthodontic return-visits, all procedures related to the orthodontic practice should be strictly performed with preventive measures to control the potential transmission of SARS-CoV-2. A study from Jordan found that although most Jordanian dentists were aware of COVID-19 symptoms, mode of transmission, infection control and measures in dental clinic, they had limited knowledge of the extra precautionary measures that are essential to protect the dental staffs and other patients from SARS-CoV-2 infection.
    keywords: coronavirus; cov-2; covid-19; infection; patients; practice; sars; transmission; use
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        item: #7088 of 7819
          id: cord-346995-2e84y1hl
      author: Hoang, Van Minh
       title: Describing the pattern of the COVID-19 epidemic in Vietnam
        date: 2020-06-26
       words: 2417
      flesch: 51
     summary: COVID-19 suspect cases: (1) People developing any symptoms of fever and acute respiratory infections and having a travel history from epidemic areas within 14 days prior to symptom onset; or (2) People having any respiratory symptoms and having any of the following epidemic factors that appear within 14 days prior to symptom onset: (i) close contact with COVID-19 confirmed/suspected cases, or (ii) working in a health facility that treats COVID-19 and contact with COVID-19 patients [7] . • As of 18 May 2020, the cumulative number of COVID-19 cases detected in Vietnam was 324, 16 cases from 4 cities and provinces in the first phase (during 20 days, 0.8 cases detected per day) and 308 cases from 35 cities, provinces in the second phase (during 76 days, 4.1 cases detected per day).
    keywords: cases; covid-19; health; phase; vietnam
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        item: #7089 of 7819
          id: cord-346998-01i6zxv8
      author: Kulkarni, Spoorthy
       title: COVID-19 and hypertension
        date: 2020-05-20
       words: 2586
      flesch: 41
     summary: Epub ahead of print 27 Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9 SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Cardiac angiotensin-(1-12) expression and systemic hypertension in rats expressing the human angiotensinogen gene ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury Angiotensinconverting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target A pilot clinical trial of recombinant human angiotensin-converting enzyme 2 in acute respiratory distress syndrome Acute respiratory distress syndrome leads to reduced ratio of ACE/ ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics Elevated plasma angiotensin converting enzyme 2 activity is an independent predictor of major adverse cardiac events in patients with obstructive coronary artery disease Genetic Ace2 deficiency accentuates vascular inflammation and atherosclerosis in the ApoE knockout mouse Genetic predisposition to acute respiratory distress syndrome in patients with severe sepsis Association between insertion/deletion polymorphism in angiotensin-converting enzyme gene and acute lung injury/acute respiratory distress syndrome: a meta-analysis Effect of angiotensin converting enzyme gene I/D polymorphism and its expression on clinical outcome in acute respiratory distress syndrome Angiotensin-converting enzyme I/D polymorphism and acute respiratory distress syndrome Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Treatment with ACE-inhibitors is associated with less severe disease with SARS-Covid-19 infection in a multi-site UK acute Hospital Trust. 8 The controversy regarding continuing or discontinuing angiotensin-converting enzyme inhibitors (ACEi) and angiotensin receptor blockers (ARBs) in COVID-19 patients arose after it became apparent that SARS-CoV uses angiotensin-converting enzyme 2 (ACE2) to gain entry in host cells.
    keywords: ace2; angiotensin; covid-19; hypertension; patients; receptor; sars
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        item: #7090 of 7819
          id: cord-347013-nt6jmmcw
      author: Retzlaff, Kimberly J.
       title: COVID‐19 Emergency Management Structure and Protocols
        date: 2020-08-28
       words: 2210
      flesch: 37
     summary: Perioperative team members also have excelled at innovation through the development and implementation of new practice tools to help manage the pandemic response. Perioperative leaders have shown agile responses, including quickly pulling together and mobilizing incident command centers, augmenting and modifying existing emergency management protocols, working together to agree on COVID-19 clinical protocols, and enhancing communication efforts with their teams to keep everyone apprised of the rapidly changing situation.
    keywords: care; covid-19; health; information; leaders; members; team
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        item: #7091 of 7819
          id: cord-347024-8fhb0j68
      author: Dang, Q.
       title: COVID-19 In Shang Hai: It is Worth Learning from the Successful Experience in Preventing and Controlling the Overseas Epidemic Situation
        date: 2020-05-16
       words: 4072
      flesch: 51
     summary: We established a variety of regression models to fit the existing growth curve, and predicted the growth of Shanghai cases from April 4th to 19th without blocking international traffic. Then, three regression models were used to establish regression models to fit the cumulative case growth data from January 19 to April 4 in Shanghai.
    keywords: cases; countries; epidemic; model; network; regions; regression; shanghai
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        item: #7092 of 7819
          id: cord-347030-yx3j6373
      author: Cao, Xuetao
       title: COVID-19: immunopathology and its implications for therapy
        date: 2020-04-09
       words: 1525
      flesch: 30
     summary: Convalescent plasma containing neutralizing antibodies has been used to treat a small number of patients with severe disease, and preliminary results show clinical improvement in 5 of 5 critically ill patients with COVID-19 who developed ARDS 8 . However, two studies, based on the analysis of 222 and 173 patients with COVID-19, respectively, reported that patients with severe disease frequently had an increased IgG response and a higher titre of total antibodies, which was associated with worse outcome 5, 9 .
    keywords: cov-2; covid-19; patients; sars
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        item: #7093 of 7819
          id: cord-347048-qqft4yc9
      author: Araten, David J.
       title: Mild Clinical Course of COVID-19 in 3 Patients Receiving Therapeutic Monoclonal Antibodies Targeting C5 Complement for Hematologic Disorders
        date: 2020-09-12
       words: 2176
      flesch: 50
     summary: The mild cases of SARS-CoV-2 infection in these 3 patients may have been related to anti-complement therapy, as suggested by preclinical models and reports of other patients who have received anti-complement therapy for COVID-19. This raises the question of whether patients on anti-complement therapy could be protected from COVID-19.
    keywords: complement; covid-19; eculizumab; patients; sars; year
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        item: #7094 of 7819
          id: cord-347058-kejcwlng
      author: Akbari, Hamed
       title: The role of cytokine profile and lymphocyte subsets in the severity of coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis
        date: 2020-07-29
       words: 3258
      flesch: 32
     summary: SAA, another important factor capable of improving inflammatory response through activation of chemokine and induction of chemotaxis even at a very low concentration [53] , was found to have elevated circulating levels in severe patients and both were significantly related to COVID-J o u r n a l P r e -p r o o f apoptotic factor The exhaustion of CD8+ T cells in severe patients J o u r n a l P r e -p r o o f may reduce their cellular immune response to SARS-CoV-2.
    keywords: cases; characteristics; clinical; coronavirus; covid-19; disease; patients; studies; study
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        item: #7095 of 7819
          id: cord-347081-g96cxamu
      author: Picchio, Camila A.
       title: The impact of the COVID-19 pandemic on harm reduction services in Spain
        date: 2020-11-04
       words: 4481
      flesch: 48
     summary: Harm reduction centres are often linked to social services, mental health services, and infectious disease testing, in addition to tools and services that help to reduce the harms associated with injecting drugs. While harm reduction centres have been reported in 13 of the 17 autonomous communities, often these centres have insufficient data or resources for proper monitoring of In order to better understand the effect of the COVID-19 pandemic on harm reduction service provision in Spain, we report service utilisation, operating hours, and provision of harm reduction services such as OST, DAAs, and ART, infectious disease testing [hepatitis B and C viruses (HBV, HCV), human immunodeficiency virus (HIV), and tuberculosis (TB)], and mental health services during the pandemic and for the same period one year earlier.
    keywords: centres; covid-19; drugs; harm; people; pwud; reduction; services; testing
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        item: #7096 of 7819
          id: cord-347090-sqw7n1v2
      author: Rodriguez-Gonzalez, Moises
       title: New onset severe right ventricular failure associated with COVID-19 in a young infant without previous heart disease
        date: 2020-06-16
       words: 1823
      flesch: 36
     summary: 9 Based on our findings, the screening of myocardial dysfunction and pulmonary hypertension through cardiac biomarkers or echocardiography could be beneficial in severe COVID-19 paediatric cases, even if they do not fulfil case definition criteria for multisystem inflammatory syndrome. key: cord-347090-sqw7n1v2 authors: Rodriguez-Gonzalez, Moises; Rodríguez-Campoy, Patricia; Sánchez-Códez, Maria; Gutiérrez-Rosa, Irene; Castellano-Martinez, Ana; Rodríguez-Benítez, Amado title: New onset severe right ventricular failure associated with COVID-19 in a young infant without previous heart disease date: 2020-06-16 journal: Cardiology in the young DOI: 10.1017/s1047951120001857 sha: doc_id: 347090 cord_uid: sqw7n1v2 We present our recent experience with a 6-month-old infant with a personal history of short bowel syndrome that presented with fever, cyanosis, and cardiogenic shock secondary to severe pulmonary hypertension and right ventricular failure without pulmonary thromboembolism.
    keywords: children; covid-19; disease; sars; syndrome
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        item: #7097 of 7819
          id: cord-347091-wbjpa5st
      author: Davis, Matthew R.
       title: That Escalated Quickly: Remdesivir's Place in Therapy for COVID-19
        date: 2020-07-10
       words: 5108
      flesch: 40
     summary: The Lancet Remdesivir for 5 or 10 days in patients with severe Covid-19 Covid-19 in critically ill patients in the Seattle Region -case series Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 Pneumonia in Wuhan, China Clinical characteristics of coronavirus disease 2019 in China NIH Clinical Trial Shows Remdesivir Accelerates Recovery from Advanced COVID-19 Remdesivir for the treatment of Covid-19-preliminary report Worsening renal function in patients with baseline renal impairment treated with intravenous voriconazole: a systematic review Evaluation of sulfobutylether-beta-cyclodextrin (SBECD) accumulation and voriconazole pharmacokinetics in critically ill patients undergoing continuous renal replacement therapy Gilead Announces Results From Phase 3 Trial of Remdesivir in Patients With Moderate COVID-19. Since the publication of this review, results from two randomized trials evaluating remdesivir for hospitalized patients with COVID-19 were published.
    keywords: clinical; covid-19; data; day; days; oxygen; patients; remdesivir
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        item: #7098 of 7819
          id: cord-347104-h168kqjn
      author: Ghosh, Ritwik
       title: A case of area postrema variant of neuromyelitis optica spectrum disorder following SARS-CoV-2 infection
        date: 2020-11-11
       words: 2611
      flesch: 24
     summary: Annals of the rheumatic diseases Neuromyelitis optica spectrum disorder associated with dengue virus infection The pathology of an autoimmune astrocytopathy: lessons learned from neuromyelitis optica Neuromyelitis optica spectrum disorder and varicella-zoster infection Acute necrotizing myelitis and acute motor axonal neuropathy in a COVID-19 patient Human molecular chaperones share with SARS-CoV-2 antigenic epitopes potentially capable of eliciting autoimmunity against endothelial cells: possible role of molecular mimicry in COVID-19 HIV infection associated neuromyelitis optica spectrum disorder: Clinical features, imaging findings, management and outcomes Acute transverse myelitis after COVID-19 pneumonia A case report and MRI findings Molecular mimicry may explain multi-organ damage in COVID-19 Neurological injuries in COVID-19 patients: direct viral invasion or a bystander injury after infection of epithelial/endothelial cells Potential neuroinvasive pathways of SARS-CoV-2: Deciphering the J o u r n a l P r e -p r o o f Journal Pre-proof spectrum of neurological deficit seen in coronavirus disease-2019 (COVID-19) Does SARS-CoV-2 Trigger Stress-InducedAutoimmunity by Molecular Mimicry?
    keywords: acute; covid-19; infection; myelitis; optica; sars
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        item: #7099 of 7819
          id: cord-347109-vgubi2k8
      author: Okoi, Obasesam
       title: How health inequality affect responses to the COVID-19 pandemic in Sub-Saharan Africa
        date: 2020-07-10
       words: 2326
      flesch: 36
     summary: key: cord-347109-vgubi2k8 authors: Okoi, Obasesam; Bwawa, Tatenda title: How health inequality affect responses to the COVID-19 pandemic in Sub-Saharan Africa date: 2020-07-10 journal: World Dev DOI: 10.1016/j.worlddev.2020.105067 sha: doc_id: 347109 cord_uid: vgubi2k8 The COVID-19 outbreak has infected millions of people across the world, caused hundreds of thousands of deaths, and collapsed national economies. Various governments have developed policies to address health inequality and its social determinants (Owusu-Addo, Renzaho & Smith, 2020).
    keywords: africa; covid-19; handwashing; health; inequalities; saharan
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        item: #7100 of 7819
          id: cord-347121-5drl3xas
      author: Farah, I.
       title: A global omics data sharing and analytics marketplace: Case study of a rapid data COVID-19 pandemic response platform.
        date: 2020-09-29
       words: 16890
      flesch: 43
     summary: Third, using the platform as a repository for research data during a peer-review publication process. Publishing research data to an open platform with audit features and data provenance increases the chance of reproducibility and to have reliable assurances for the integrity of the raw data.
    keywords: access; analysis; covid-19; data; data sharing; datasets; disease; healthcare; information; license; medrxiv; need; new; pandemic; patient; peer; pipelines; platform; preprint; public; research; researchers; review; share; sharing; shivom; user
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        item: #7101 of 7819
          id: cord-347126-hvrly37e
      author: Stanton, Robert
       title: Depression, Anxiety and Stress during COVID-19: Associations with Changes in Physical Activity, Sleep, Tobacco and Alcohol Use in Australian Adults
        date: 2020-06-07
       words: 5481
      flesch: 40
     summary: That is, those with normal levels of depression symptoms reported a small negative change (−0.42 points), while for those with extremely severe symptoms, the change in composite health behavior change score was more than three times greater (−1.45). An online survey was distributed in April 2020 and included measures of depression, anxiety, stress, physical activity, sleep, alcohol intake and cigarette smoking.
    keywords: activity; anxiety; change; covid-19; depression; health; pandemic; sleep; stress
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        item: #7102 of 7819
          id: cord-347151-ni94qi4r
      author: Vespa, Edoardo
       title: Liver tests abnormalities in COVID-19: trick or treat?
        date: 2020-05-27
       words: 692
      flesch: 46
     summary: In conclusion, we think that although LFTs alterations are common in hospitalized Covid-19 patients, it is still unclear whether they carry any prognostic value. [1] , which describes the role of liver function tests (LFTs) in a population of hospitalized patients with COVID-19.
    keywords: liver; patients
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        item: #7103 of 7819
          id: cord-347185-ttf8oigk
      author: Hart, Andrew
       title: Editorial - Covid-19
        date: 2020-05-20
       words: 2766
      flesch: 38
     summary: We must advocate for a return to the delivery of high quality plastic surgical care, giving primacy to patient care approaches that are to the clear benefit of societies and economies, and not allow our specialty to be portrayed as defending vanity or individual greed. When healthcare colleagues are being placed at risk of severe disease or death through patient contact (particularly in the face of limited protective equipment or training), we must all support social measures to minimise case numbers -virtual clinical care systems should be used to enable patients not to travel.
    keywords: care; colleagues; covid-19; healthcare; plastic; public; risk; surgery
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        item: #7104 of 7819
          id: cord-347186-tbtmqmpr
      author: Acharya, Yogesh
       title: Chloroquine and hydroxychloroquine as a repurposed agent against COVID-19: a narrative review
        date: 2020-08-04
       words: 3554
      flesch: 37
     summary: Epub ahead of print 11 A randomized trial of hydroxychloroquine as postexposure prophylaxis for Covid-19 Recoverytrial.net Breakthrough: chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 Epub ahead of print 10 A systematic review of the prophylactic role of chloroquine and hydroxychloroquine in coronavirus disease-19 (COVID-19) Virological and clinical cure in COVID-19 patients treated with hydroxychloroquine: a systematic review and meta-analysis A rapid systematic review of clinical trials utilizing chloroquine and hydroxychloroquine as a treatment for COVID-19 Hydroxychloroquine in patients with COVID-19: a systematic review and meta-analysis FDA cautions use of hydroxychloroquine/chloroquine for COVID-19 Coronavirus disease 2019 (COVID-19) treatment guidelines COVID-19 coronavirus research has overall low methodological quality thus far: case in point for These inhibitory effects were noted with CQ treatment both before and after exposure to the SARS virus, suggesting its prophylactic as well as therapeutic utility.
    keywords: chloroquine; coronavirus; covid-19; evidence; hcq; hydroxychloroquine; patients; studies
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        item: #7105 of 7819
          id: cord-347189-i9rzo3j0
      author: Lorusso, Domenica
       title: Clinical research disruption in the post-COVID-19 era: will the pandemic lead to change?
        date: 2020-10-13
       words: 3313
      flesch: 33
     summary: Moreover, less than 5% of cancer clinical trials adequately accrue ethnic minorities (OR 0.7 with respect to white patients in cancer clinical trials) 10 and a potential explanation is that travel burden to centres mandated by specific trials (eg, rare cancers) implies time off from work and family commitments for both patients and careers leading to financial repercussions. The effect of telehealth interventions on quality of life of cancer patients: a systematic review and meta-analysis Participation in cancer clinical trials: race-, sex-, and age-based disparities At what cost to clinical trial enrollment?
    keywords: cancer; care; covid-19; data; pandemic; patients; research; time; trial
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        item: #7106 of 7819
          id: cord-347199-slq70aou
      author: Safta, Cosmin
       title: Characterization of partially observed epidemics through Bayesian inference: application to COVID-19
        date: 2020-10-07
       words: 8415
      flesch: 49
     summary: This was somewhat expected based on the evolution of the daily counts of symptomatic cases and the functional form that couples the infection rate and incubation models. The epidemiological model is formulated in Sect. 2, with postulated forms for the infection rate curve and the derivation of the prediction for daily new cases; we also discuss a filtering approach that is applied to the data before using it to infer model parameters.
    keywords: cases; covid-19; daily; data; distribution; incubation; infection; model; number; parameters; rate; results; time
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        item: #7107 of 7819
          id: cord-347225-gh51ag2x
      author: Fu, Weihui
       title: A clinical pilot study on the safety and efficacy of aerosol inhalation treatment of IFN-κ plus TFF2 in patients with moderate COVID-19
        date: 2020-07-29
       words: 4926
      flesch: 42
     summary: The prognosis of COVID-19 patients has been associated with the levels of pro-inflammatory cytokines in the peripheral blood [27] , IL-6 receptor blocking antibodies, Tocilizumab therapy have been applied to counteract the cytokine storm in severe COVID-19 patients [29] . Up to date, the therapeutic efficacy of HCQ in COVID-19 patients remains controversial [9, 10] , clinical trials to test the efficacy of hydroxychloroquine are ongoing.
    keywords: control; covid-19; days; group; ifn; patients; study; tff2; treatment; trial
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        item: #7108 of 7819
          id: cord-347238-yacn6xqk
      author: Angurala, Mohit
       title: An Internet of Things Assisted Drone Based Approach to Reduce Rapid Spread of Covid-19
        date: 2020-07-02
       words: 2367
      flesch: 57
     summary: The proposed mechanism can effectively improve the treatment process of Covid-19 patients. Doctors and medical staff are most prone to the infection and if their safety is not considered to be important, then it may lead to spread of infection to other patients who suffer from other medical problems and are admitted to the hospital or visits hospital for regular checkups.
    keywords: covid-19; drone; layer; number; patient; spread
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        item: #7109 of 7819
          id: cord-347245-35naeuo7
      author: Zhou, Yongjie
       title: The prevalence and risk factors of psychological disturbances of frontline medical staff in China under the COVID-19 epidemic: workload should be concerned
        date: 2020-08-26
       words: 2892
      flesch: 42
     summary: Although attention has been paid to the mental health of medical staff in the fight against COVID-19 , few studies have investigated the psychological disturbances and risk factors of frontline medical staff, especially considering the impact of the work conditions, such as workload. key: cord-347245-35naeuo7 authors: Zhou, Yongjie; Wang, Wenjuan; Sun, Yanping; Qian, Wei; Liu, Zhengkui; Wang, Ruoxi; Qi, Ling; Yang, Jiezhi; Song, Xiuli; Zhou, Xin; Zeng, Lingyun; Liu, Tiebang; Li, Zezhi; Zhang, Xiangyang title: The prevalence and risk factors of psychological disturbances of frontline medical staff in China under the COVID-19 epidemic: workload should be concerned date: 2020-08-26 journal: J Affect Disord DOI: 10.1016/j.jad.2020.08.059 sha: doc_id: 347245 cord_uid: 35naeuo7 BACKGROUND: To our best knowledge, this was the first time to investigate the prevalence and risk factors of psychological disturbances, including depression, anxiety, somatization symptoms, insomnia and suicide, among frontline medical staff, who were working with the COVID-10 infected patients directly.
    keywords: anxiety; frontline; insomnia; medical; risk; staff; symptoms
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        item: #7110 of 7819
          id: cord-347260-7glhaow6
      author: Bi, Xiaojie
       title: Prediction of severe illness due to COVID-19 based on an analysis of initial Fibrinogen to Albumin Ratio and Platelet count
        date: 2020-05-05
       words: 2273
      flesch: 50
     summary: Compared with non-severe patients, the Median time from illness onset to admission was much longer in severe patients (3 days vs. 2 days, P = .034). key: cord-347260-7glhaow6 authors: Bi, Xiaojie; SU, Zhengxian; Yan, Haixi; Du, Juping; Wang, Jing; Chen, Linping; Peng, Minfei; Chen, Shiyong; Shen, Bo; Li, Jun title: Prediction of severe illness due to COVID-19 based on an analysis of initial Fibrinogen to Albumin Ratio and Platelet count date: 2020-05-05 journal: Platelets DOI: 10.1080/09537104.2020.1760230 sha: doc_id: 347260 cord_uid: 7glhaow6 Concomitant coagulation disorder can occur in severe patients withCOVID-19, but in-depth studies are limited.
    keywords: analysis; covid-19; disease; patients; plt; study
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        item: #7111 of 7819
          id: cord-347262-q88g1561
      author: Schutzer‐Weissmann, J.
       title: Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection risk during elective peri‐operative care: a narrative review
        date: 2020-07-11
       words: 4759
      flesch: 31
     summary: Chung-Hua Liu Hsing Ping Hsueh Risk factors for SARS transmission from patients requiring intubation: A multicentre investigation in Toronto Transmission of severe acute respiratory syndrome during intubation and mechanical ventilation SARS among Critical Care Nurses Illness in intensive care staff after brief exposure to severe acute respiratory syndrome Assessing the evidence base for medical procedures which create a higher risk of respiratory infection transmission from patient to healthcare worker COVID-19 and risks posed to personnel during endotracheal intubation Exposure to a surrogate measure of contamination from simulated patients by Emergency Department personnel wearing Personal Protective Equipment Toward understanding the risk of secondary airborne infection: emission of respirable pathogens Evaluation of bioaerosol exposures during hospital bronchoscopy examinations Droplet fate in indoor environments, or can we prevent the spread of infection? Exhaled droplets due to talking and coughing Size distribution and sites of origin of droplets expelled from the human respiratory tract during expiratory activities Airborne transmission of severe acute respiratory syndrome coronavirus-2 to healthcare workers: a narrative review Turbulent Gas Clouds and Respiratory Pathogen Emissions: The studies upon which the WHO list of aerosol-generating procedures is based do not provide any direct evidence that tracheal intubation itself increases the risk of SARS transmission.
    keywords: aerosol; cov-2; covid-19; healthcare; infection; intubation; risk; sars; tracheal; transmission; workers
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        item: #7112 of 7819
          id: cord-347263-ci6mv72z
      author: Berekashvili, k.
       title: Etiologic Subtypes of Ischemic Stroke in SARS-COV-2 Virus patients
        date: 2020-05-08
       words: 2974
      flesch: 51
     summary: The median age of large vessel stroke patients was 46 years, the youngest being in the twenties. Methods: Over the last 6 weeks, data from four centers in New York City were collected to review the possible ischemic stroke types seen in COVID-19 positive patients.
    keywords: author; covid-19; medrxiv; patients; preprint; review
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        item: #7113 of 7819
          id: cord-347277-8bmcd22v
      author: Huang, Ying hui
       title: The respiratory sound features of COVID-19 patients fill gaps between clinical data and screening methods
        date: 2020-04-10
       words: 3802
      flesch: 51
     summary: key: cord-347277-8bmcd22v authors: Huang, Ying hui; Meng, Si jun; Zhang, Yi; Wu, Shui sheng; Zhang, Yu; Zhang, Ya wei; Ye, Yi xiang; Wei, Qi feng; Zhao, Nian gui; Jiang, Jian ping; Ji, Xiao ying; Zhou, Chun xia; Zheng, Chao; Zhang, Wen; Xie, Li zhong; Hu, Yong chao; He, Jian quan; Chen, Jian; Wang, Wang yue; Zhang, Chang hua; Cao, Liming; Xu, Wen; Lei, Yunhong; Jian, Zheng hua; Hu, Wei ping; Qin, Wen juan; Wang, Wan yu; He, Yu long; Xiao, Hang; Zheng, Xiao fang; Hu, Yi Qun; Pan, Wen Sheng; Cai, Jian feng title: The respiratory sound features of COVID-19 patients fill gaps between clinical data and screening methods date: 2020-04-10 journal: nan DOI: 10.1101/2020.04.07.20051060 sha: doc_id: 347277 cord_uid: 8bmcd22v Background: The 2019 novel coronavirus (COVID-19) has continuous outbreaks around the world. This study intends to leverage a remote electronic stethoscope to collect the lung auscultation characteristics of COVID-19 patients, which makes up the lack of existing COVID-19 clinical data.
    keywords: 0(0; auscultation; breath; covid-19; lung; patients; results; sounds; time
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        item: #7114 of 7819
          id: cord-347280-jpwf55l6
      author: Skevaki, Chrysanthi
       title: Laboratory characteristics of patients infected with the novel SARS-CoV-2 virus
        date: 2020-06-21
       words: 3076
      flesch: 30
     summary: Although patients with severe COVID-19 seem to have higher rates of liver dysfunction, it is reassuring that the levels of ALT, AST, TBIL, GGT in COVID-19 patients were not significantly different in compared with hospitalized community-acquired pneumonia patients and even the median or average transaminase level in severe COVID-19 patients was lower than twice upper reference limit 4, 36, 37 . key: cord-347280-jpwf55l6 authors: Skevaki, Chrysanthi; Fragkou, Paraskevi C.; Cheng, Chongsheng; Xie, Min; Renz, Harald title: Laboratory characteristics of patients infected with the novel SARS-CoV-2 virus date: 2020-06-21 journal: J Infect DOI: 10.1016/j.jinf.2020.06.039 sha: doc_id: 347280 cord_uid: jpwf55l6 A subgroup of COVID-19 patients develop very severe disease with requirement for ICU treatment, ventilation, and ECMO therapy.
    keywords: cases; china; covid-19; disease; levels; patients; risk; sars; study
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        item: #7115 of 7819
          id: cord-347288-ub0l4mov
      author: Yin, Xi
       title: Assessment of the Severity of Coronavirus Disease: Quantitative Computed Tomography Parameters versus Semiquantitative Visual Score
        date: 2020-06-11
       words: 2867
      flesch: 39
     summary: Some studies have estimated the severity of COVID-19 based on CT characteristics (12, 13) or semiquantitative visual CT scores (14, 15) . We compared the AUCs between the quantitative CT CT Characteristics and Semiquantitative Visual Score of COVID-19 Table 1 shows the comparison of the imaging characteristics, namely, interstitial thickening, air bronchogram, axial plane distribution, and unilateral or bilateral involvement, between groups 1 and 2.
    keywords: covid-19; parameters; patients; score; severity
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        item: #7116 of 7819
          id: cord-347289-3yi5tz04
      author: Poon, L. . C.
       title: ISUOG Interim Guidance on coronavirus disease 2019 (COVID‐19) during pregnancy and puerperium: information for healthcare professionals – an update
        date: 2020-06-01
       words: 8045
      flesch: 35
     summary: Although not yet validated in COVID-19 pregnant patients, a modified early obstetric warning score (MEOWS) can be used to enable early recognition of critical illness 50, 51 . Miscarried embryos/fetuses and placentae of COVID-19 pregnant women should be treated as infectious tissues and should be disposed of appropriately.
    keywords: care; cases; coronavirus; cov-2; covid-19; delivery; disease; infection; obstetric; patients; pregnancy; pregnant; risk; sars; transmission; women
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        item: #7117 of 7819
          id: cord-347308-l19snjyf
      author: García-Howard, Marcos
       title: Case Report: Benign Infantile Seizures Temporally Associated With COVID-19
        date: 2020-08-06
       words: 3102
      flesch: 41
     summary: Moreover, COVID-19 may present in infants as non-febrile seizures, triggering early onset seizures in infants with a genetic predisposition. Moreover, COVID-19 may present in infants as non-febrile seizures, triggering early onset seizures in infants with a genetic predisposition.
    keywords: case; children; coronavirus; covid-19; infections; sars; seizures
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        item: #7118 of 7819
          id: cord-347333-h899xkfy
      author: Li, Z.
       title: From Community Acquired Pneumonia to COVID-19: A Deep Learning Based Method for Quantitative Analysis of COVID-19 on thick-section CT Scans
        date: 2020-04-23
       words: 2965
      flesch: 53
     summary: Recently, several deep learning based AI systems 11 were developed to differentiate the COVID-19 and community acquired pneumonia (CAP) CT images were reconstructed with 5mm slice 56 thickness and the soft reconstruction kernel.
    keywords: covid-19; license; preprint
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        item: #7119 of 7819
          id: cord-347349-caz5fwl1
      author: Yu, Xinhua
       title: Distinctive trajectories of COVID-19 epidemic by age and gender: a retrospective modeling of the epidemic in South Korea
        date: 2020-07-02
       words: 3803
      flesch: 49
     summary: In summary, in South Korea, and likely in other countries, COVID-19 epidemic processes had distinctive dynamic patterns among age and gender groups. key: cord-347349-caz5fwl1 authors: Yu, Xinhua; Duan, Jiasong; Jiang, Yu; Zhang, Hongmei title: Distinctive trajectories of COVID-19 epidemic by age and gender: a retrospective modeling of the epidemic in South Korea date: 2020-07-02 journal: Int J Infect Dis DOI: 10.1016/j.ijid.2020.06.101 sha: doc_id: 347349 cord_uid: caz5fwl1 OBJECTIVES:
    keywords: age; cases; covid-19; epidemic; people
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        item: #7120 of 7819
          id: cord-347351-emdj66vj
      author: Kampf, Günter
       title: Potential sources, modes of transmission and effectiveness of prevention measures against SARS-CoV-2
        date: 2020-09-18
       words: 10293
      flesch: 41
     summary: [Chinese journal of preventive medicine Indirect Virus Transmission in Cluster of COVID-19 Cases Familial cluster of COVID-19 infection from an asymptomatic Potential Presymptomatic Transmission of SARS-CoV-2 Asymptomatic and Human-to-Human Transmission of SARS-CoV-2 in a 2-Family Cluster Presumed Asymptomatic Carrier Transmission of COVID-19 The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) Covid-19: four fifths of cases are asymptomatic, China figures indicate COVID-19 transmission through asymptomatic carriers is a challenge to containment. Table III summarizes the frequency and magnitude of SARS-CoV-2 viral RNA loads in respiratory tract samples obtained from COVID-19 patients.
    keywords: air; asymptomatic; cases; coronavirus; cov-2; covid-19; detection; disease; infection; patients; respiratory; rna; samples; sars; study; surfaces; transmission
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        item: #7121 of 7819
          id: cord-347356-uc9dqhyq
      author: Cooper, TJ
       title: Coronavirus disease 2019 (COVID‐19) outcomes in HIV/AIDS patients: a systematic review
        date: 2020-07-15
       words: 3953
      flesch: 51
     summary: We define controlled HIV infection as an undetectable viral load and a CD4 count ≥ 200 cells/lL. A comprehensive literature search was carried out in Global Health, SCOPUS, Medline and EMBASE to identify articles that discussed HIV-positive patients and the clinical implications of HIV infection in COVID-19 in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) guidelines [13] . Event background COVID-19 COVID-19 and Multiorgan Response Covid-19: risk factors for severe disease and death Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis Rethinking high-risk groups in COVID-19 Undetectable = untransmittable and your health: the personal benefits of early and continuous therapy for HIV infection Global statistics Partners of people on ART -a new evaluation of the risks (The PARTNER Study): design and methods multicentre, prospective, observational study ART in HIV-positive persons with low pretreatment viremia: results from the START trial SARS-CoV-2 and HIV Interim guidance for COVID-19 and persons with HIV COVID-19 and persons with HIV Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement Study Quality Assessment Tools Encephalopathy and seizure activity in a COVID-19 well controlled HIV patient The reflection on an AIDS patient with asymptomatic COVID-19 -abstract -Europe PMC COVID-19 in patients with HIV: clinical case series COVID-19 in people living with human immunodeficiency virus: a case series of 33 patients Early Virus Clearance and Delayed Antibody Response in a Case of Coronavirus Disease 2019 (COVID-19) With a History of Coinfection With Human Immunodeficiency Virus Type 1 and Hepatitis C Virus Outcomes among HIV-positive patients hospitalized with COVID-19 HIV-associated pneumocystis pneumonia Case report: one case of coronavirus desease 2019(COVID-19) in patient co-Nfected by HIV with a low CD4+ T cell count Community-acquired bacterial pneumonia in adult HIVinfected patients Global strategies to prevent bacterial pneumonia in adults with HIV disease Severe bacterial nonaids infections in HIV-positive persons: incidence rates and risk factors Bacterial pneumonia, HIV therapy, and disease progression among HIV-infected women in the HIV epidemiologic research (HER) study Mortality and causes of death in people diagnosed with HIV in the era of highly active antiretroviral therapy compared with the general population: an analysis of a national observational cohort COVID-19) and HIV -update from the British HIV Association (BHIVA)
    keywords: covid-19; hiv; infection; outcomes; patients; plhiv; risk; sars
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        item: #7122 of 7819
          id: cord-347360-l1v93av4
      author: Shapira, Guy
       title: Ethnic differences in alpha‐1 antitrypsin deficiency allele frequencies may partially explain national differences in COVID‐19 fatality rates
        date: 2020-09-22
       words: 2441
      flesch: 29
     summary: Highlighted region represents the 95% confidence interval Why does Japan have so few cases of COVID-19? Socio-demographic and epidemiological consideration of Africa's COVID-19 response: what is the possible pandemic course SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor The anticoagulant nafamostat potently inhibits SARS-CoV-2 S protein-mediated fusion in a cell fusion assay system and viral infection in vitro in a cell-type-dependent manner Geographical overlap between alpha-1 antitrypsin deficiency and COVID-19 infection in Italy: casual or causal? Alpha-1-antitrypsin: a possible host protective factor against Covid-19 Alpha-1 antitrypsin Pi*SZ genotype: estimated prevalence and number of SZ subjects worldwide Liver disease in alpha-1 antitrypsin deficiency: current approaches and future directions An interactive web-based dashboard to track COVID-19 in real time Characterization of the inflammatory response to severe COVID-19 illness High serum level of IL-17 in patients with chronic obstructive pulmonary disease and the alpha-1 antitrypsin PiZ Allele COVID-19: a case for inhibiting IL-17? Distinct anti-inflammatory properties of alpha1-antitrypsin and corticosteroids reveal unique underlying mechanisms of action Reduced 25(OH) vitamin D association with lower alpha-1-antitrypsin blood levels in type 2 diabetic patients Association of vitamin D status and other clinical characteristics with COVID-19 test results The use of proteomics in the discovery of serum biomarkers from patients with severe acute respiratory syndrome The effect of Bacillus Calmette-Guérin (BCG) vaccination in preventing sever infectious respiratory diseases other than TB: implications for the COVID-19 pandemic BCG vaccination in humans elicits trained immunity via the hematopoietic progenitor compartment Alpha 1 antitrypsin is an inhibitor of the SARS-CoV2-priming protease TMPRSS2 Alpha-1 antitrypsin inhibits SARS-CoV-2 infection vitro inhibition of human TMPRSS2 by alpha-1 antitrypsin, thus suggesting that it might be effective as a COVID-19 treatment. Until additional candidate alleles are found to better explain such national differences, the population variations in the allele frequencies of alpha-1 antitrypsin deficiency present a possible genetic explanation for the varying national COVID-19 burden.
    keywords: alpha-1; antitrypsin; countries; covid-19; deficiency; infection; rates
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        item: #7123 of 7819
          id: cord-347381-nn6jqqy5
      author: Mazzola, Santina M.
       title: Maintaining Perioperative Safety in Uncertain Times: COVID‐19 Pandemic Response Strategies
        date: 2020-09-29
       words: 3415
      flesch: 32
     summary: AORN J DOI: 10.1002/aorn.13195 sha: doc_id: 347381 cord_uid: nn6jqqy5 nan demic has presented health care leaders with the unprecedented challenge of maintaining patient and staff member safety amidst the rapid spread of a novel virus. As a result, health care leaders and workers experienced confusion about which recommendations they should follow.
    keywords: care; covid-19; health; leaders; members; patients; ppe; respirators; staff
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        item: #7124 of 7819
          id: cord-347384-lwrrm5kx
      author: Klocker, J.
       title: Operieren, Absagen, Verschieben oder Selektionieren?: Ergebnisse einer Umfrage unter gefäßchirurgischen Zentren während der Covid-19-Krise in Österreich
        date: 2020-09-02
       words: 2925
      flesch: 32
     summary: Allerdings wurden in der Hälfte der Institutionen die den gefäßchirurgischen Abteilungen zugeordneten Bettenressourcen reduziert. Die Befristung der Einschränkungen der OP-Kapazitäten (vordefinierte Zeitintervalle) haben die einzelnen Abteilungen sehr unterschiedlich eingeschätzt: 5 bis 8 Wochen (17 %), 9 bis 12 Wochen (33 %), 3 bis 6 Monate (17 %) oder 6 bis 9 Monate (33 %).
    keywords: als; auch; auf; bis; bzw; covid-19; der; die; für; gefäßchirurgischen; mit; nicht; oder; pandemie; patienten; surgery; und; verschoben; von; wurden; zentren
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        item: #7125 of 7819
          id: cord-347388-9uqgt7wb
      author: Garrido-Hermosilla, Antonio Manuel
       title: Auditoría inmunitaria de COVID-19 en el servicio de Oftalmología de un hospital de tercer nivel antes del desconfinamiento
        date: 2020-04-27
       words: 750
      flesch: 44
     summary: El principal inconveniente de estos test rápidos radica en que no resultan útiles durante los primeros días de la infección, ya que los anticuerpos frente al virus comienzan a producirse a partir del sexto día desde el inicio de los síntomas 3 . De este modo, con nuestro estudio, perseguíamos dos objetivos fundamentales: conocer si alguno de los oftalmólogos del servicio, todos sin síntomas, era un caso asintomático, y determinar si alguno había pasado la infección de forma inadvertida y presentaba inmunidad frente al virus, todo ello con vistas a tratar de planificar futuras estrategias de asistencia clínico-quirúrgica.
    keywords: covid-19; del; los; que; una
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        item: #7126 of 7819
          id: cord-347404-nv70mlae
      author: Teixeira da Silva, Jaime A.
       title: Convalescent plasma: A possible treatment of COVID-19 in India
        date: 2020-04-15
       words: 956
      flesch: 42
     summary: r e f e r e n c e s 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 Healthcare impact of COVID-19 epidemic in India: a stochastic mathematical model Review of emerging pharmacotherapy for the treatment of coronavirus disease 2019 Deployment of convalescent plasma for the prevention and treatment of COVID-19 Fcmediated antibody effector functions during respiratory syncytial virus infection and disease Treatment of 5 critically ill patients with COVID-19 with convalescent plasma There are no current effective strategies to prevent the spread, other than minimizing contact through social distancing, while no fully effective drugs to prevent or treat COVID-19 exist, although several candidate drugs and repurposed antiviral and immune-modulating pharmacotherapies are being tested or in compassionate use.
    keywords: covid-19; india; plasma
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        item: #7127 of 7819
          id: cord-347414-t88654wo
      author: Peng, Mian
       title: Successful management of seven cases of critical COVID-19 with early noninvasive-invasive sequential ventilation algorithm and bundle pharmacotherapy
        date: 2020-08-06
       words: 2754
      flesch: 43
     summary: Thus, we concluded that good outcomes for patients with critical COVID-19 can be achieved with early noninvasive–invasive sequential ventilation and bundle pharmacotherapy. In December of 2019, a cluster of patients with pneumonia of unknown cause was linked to transmission at a seafood wholesale market in Wuhan, China.
    keywords: coronavirus; covid-19; days; patients; pneumonia; sars
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        item: #7128 of 7819
          id: cord-347446-yw0nk7fo
      author: Vantarakis, A.
       title: COVID-19 and Environmental factors. A PRISMA-compliant systematic review
        date: 2020-05-15
       words: 3171
      flesch: 43
     summary: https://doi.org/10.1101 template for included studies (Cochrane Consumers and Communication 2016) . https://doi.org/10.1101 The search strategy and analysis process were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement for systematic reviews (Liberati et al. 2009; Page et al. 2018) .
    keywords: author; covid-19; medrxiv; peer; preprint; review; studies
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        item: #7129 of 7819
          id: cord-347459-8ju196uu
      author: Nikolovska, Manja
       title: “Show this thread”: policing, disruption and mobilisation through Twitter. An analysis of UK law enforcement tweeting practices during the Covid-19 pandemic
        date: 2020-10-21
       words: 9393
      flesch: 45
     summary: Looking closely at the Covid-19 themed crime tweets in particular (Fig. 3) , the majority concerned fraud (57.22%), followed by cybercrime (16.85%), general crime (13.46%) and domestic abuse (12.52%). Covid-19 general crime tweets mostly included warnings about criminals exploiting the pandemic (in general terms) and victimisation.
    keywords: analysis; covid-19; crime; data; e.g.; et al; example; fraud; media; pandemic; police; public; research; stakeholders; tweets; twitter; use
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        item: #7130 of 7819
          id: cord-347460-9vechh4x
      author: Chang, Feng-Yee
       title: Immunologic aspects of characteristics, diagnosis, and treatment of coronavirus disease 2019 (COVID-19)
        date: 2020-06-04
       words: 8058
      flesch: 38
     summary: Effect of interferon alpha and cyclosporine treatment separately and in combination on Middle East respiratory syndrome coronavirus (MERS-CoV) replication in a human in-vitro and ex-vivo culture model Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirus-specific human monoclonal antibody Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association Human monoclonal antibody combination against SARS coronavirus: synergy and coverage of escape mutants Experience of using convalescent plasma for severe acute respiratory syndrome among healthcare workers in a Taiwan hospital Convalescent plasma as a potential therapy for COVID-19 Immune evasion of porcine enteric coronaviruses and viral modulation of antiviral innate signaling Middle East respiratory syndrome coronavirusencoded ORF8b strongly antagonizes IFN-beta promoter activation: its implication for vaccine design Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies Lianhuaqingwen exerts anti-viral and antiinflammatory activity against novel coronavirus (SARS-CoV-2) It is interesting to note that higher levels of IL-1, IL-12, IFN-gamma, IL-8, and CXCL9, in addition to the cytokines and chemokines mentioned above, were also observed in SARS patients with severe diseases.
    keywords: antibodies; cells; coronavirus; cov; cov-2; covid-19; cytokine; disease; human; infection; mers; patients; protein; sars; syndrome; treatment; vaccine
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        item: #7131 of 7819
          id: cord-347480-vs57lu1f
      author: Wang, Shu
       title: Psychological distress and sleep problems when people are under interpersonal isolation during an epidemic: A nationwide multicenter cross-sectional study
        date: 2020-08-28
       words: 5258
      flesch: 45
     summary: Several studies have shown that 16.5-28.8% of people had psychological health problems during the outbreak of the COVID-19 epidemic in China, which is higher than our findings Finally, as a cross-sectional study, changes in the prevalence and severity of psychological symptoms and changes in the epidemic situation and people's recognition cannot be identified.
    keywords: anxiety; covid-19; depression; epidemic; participants; people; sampling; study; symptoms
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        item: #7132 of 7819
          id: cord-347488-th07jo7u
      author: Akseer, Nadia
       title: COVID-19 pandemic and mitigation strategies: implications for maternal and child health and nutrition
        date: 2020-06-19
       words: 3348
      flesch: 34
     summary: Where community health extension programs currently do not exist, countries may want to consider piloting or adopting such a program to supplement primary health care, as a short-or long-term solution. Targeting the most marginalized households in rural populations and urban slums could be achieved through deploying community health workers and supporting women and community members.
    keywords: care; children; community; countries; covid-19; food; health; nutrition; stunting
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        item: #7133 of 7819
          id: cord-347490-9eyq4j14
      author: Cimerman, Sergio
       title: Deep Impact of COVID-19 in the HealthCare of Latin America: the case of Brazil
        date: 2020-04-23
       words: 1080
      flesch: 51
     summary: 1, 2 In such a complex clinical scenario, the epidemiological situation of Brazil and most countries in Latin America before February 25, 2020, was already intricate, with overlapping epidemics of multiple vector-borne diseases, including especially dengue and yellow fever, but also, still struggling with long-term consequences, and endemicity, of 2014-2016 epidemics of chikungunya and Zika. 1, 4 Sadly, also the last years' vaccine coverages in multiple countries of Latin America, but also some areas of individual nations, have significantly decrease, allowing the imminent menace of imported cases and spreading with local transmission of this once not reported old diseases, such as is especially the case of measles, that in fact, due to forced migration from Venezuela arrived especially to Roraima and Amazonas to lead to thousands of cases in the region. These measures and the proper support and advice from scientific societies, such as the Brazilian Society of Infectious Diseases, in addition to the international organizations, such as the Pan-American Health Organization (PAHO) and the World Health Organization (WHO), adequately applied, will help to slow the number of new cases expected, will help to decrease them.
    keywords: brazil; cases; covid-19
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        item: #7134 of 7819
          id: cord-347492-zz3walri
      author: Chellamuthu, Girinivasan
       title: Pandemic response protocol of a non-frontline specialty in a multispecialty tertiary health care centre—a pilot model in orthopaedics
        date: 2020-05-29
       words: 3136
      flesch: 49
     summary: Institutes should take adequate steps to ensure a continuous and adequate supply of personal protective equipment (PPE) for pandemic response. The surgical group should be split into two teams: one to handle the orthopaedic workload and the other for pandemic response.
    keywords: care; covid-19; health; orthopaedic; pandemic; prep; response; specialty
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        item: #7135 of 7819
          id: cord-347500-sigm6tos
      author: Vetter, Thomas R.
       title: The Response of the Anesthesia & Analgesia Community to Coronavirus Disease 2019
        date: 2020-04-27
       words: 997
      flesch: 43
     summary: Disease containment efforts largely failed, and the WHO in March 2020 declared a global pandemic status for this insidious virus and viral disease. For coronavirus disease 2019 (COVID-19), R 0 is currently estimated to be 2-3.
    keywords: covid-19; disease; health
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        item: #7136 of 7819
          id: cord-347504-pkkh9uy4
      author: Rajhans, Vidyut
       title: Impact of COVID-19 on academic activities and way forward in Indian Optometry
        date: 2020-06-13
       words: 3083
      flesch: 40
     summary: This study is aimed to apprehend the enabling and impeding factors of these reforms, with a focus on optometry education. The scenario is prompting an urgent need for transformation of optometry education, from traditional brick mortar system to e-learning environment, imparting updated competencies in our graduating optometry professionals.
    keywords: covid-19; education; india; learning; online; optometry; survey
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        item: #7137 of 7819
          id: cord-347515-3dbx61tz
      author: de Moura, J.
       title: Deep convolutional approaches for the analysis of Covid-19 using chest X-Ray images from portable devices
        date: 2020-06-23
       words: 5807
      flesch: 32
     summary: However, the subjective appreciation of the clinical biomarkers and the variety of X-Ray images entail an inter and intra expert variability that affects the repeatability of the manual evaluation of chest X-Ray images. In both scenarios, we have to consider the complexity of analyzing chest X-Ray images capture by portable devices, which present a lower quality in comparison with other typically used images in many pulmonary computational proposals using X-Ray images.
    keywords: approaches; cases; chest; chest x; covid-19; normal; pathological; patients; ray images
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        item: #7138 of 7819
          id: cord-347535-tgou78o7
      author: Goh, Kah Kheng
       title: Zero confirmed cases: The ways we curb COVID-19 in Taiwanese prisons
        date: 2020-08-23
       words: 1618
      flesch: 46
     summary: Although no additional formal limitations were put on prisoner entry or re-re-entry from prison To minimize the risk of COVID-19 outbreak in Taiwanese prisons, several steps have been taken, including the establishment of the joint planning and central command with CECC, the prevention, control, and risk management among the prisoners, the cooperation and involvement of prison staffs, and the environment sanitizing. to the community, nevertheless, prisoners were encouraged to avoid unnecessary risk of infection. It needs to be fully acknowledged that prison health is an issue of public health.
    keywords: covid-19; health; prison; prisoners; risk
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        item: #7139 of 7819
          id: cord-347547-makm0j09
      author: Duran-Frigola, Miquel
       title: Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs
        date: 2020-07-16
       words: 1945
      flesch: 42
     summary: key: cord-347547-makm0j09 authors: Duran-Frigola, Miquel; Bertoni, Martino; Blanco, Roi; Martínez, Víctor; Pauls, Eduardo; Alcalde, Víctor; Turon, Gemma; Villegas, Núria; Fernández-Torras, Adrià; Pons, Carles; Mateo, Lídia; Guitart-Pla, Oriol; Badia-i-Mompel, Pau; Gimeno, Aleix; Soler, Nicolas; Brun-Heath, Isabelle; Zaragoza, Hugo; Aloy, Patrick title: Bioactivity Profile Similarities to Expand the Repertoire of COVID-19 Drugs date: 2020-07-16 journal: J Chem Inf Model DOI: 10.1021/acs.jcim.0c00420 sha: doc_id: 347547 cord_uid: makm0j09 [Image: see text] Our web-based resource is updated daily and can be used to dynamically search for candidates related to COVID-19 drugs with varying levels of evidence and MoA.
    keywords: compounds; covid-19; drugs; evidence; molecules
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        item: #7140 of 7819
          id: cord-347548-h5fk64p8
      author: Zarza, José
       title: Evans syndrome associated with antiphospholipid antibodies in a patient with SARS-COV-2 infection
        date: 2020-08-21
       words: 1849
      flesch: 46
     summary: Hematological findings and complications of COVID-19 Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Mechanism of thrombocytopenia in COVID-19 patients Disseminated intravascular coagulation in patients with 2019-nCoV pneumonia Thromboprophylaxis and laboratory monitoring for in-hospital Q4 patients with COVID-19 -a key: cord-347548-h5fk64p8 authors: Zarza, José; Von Horoch, Jorge; Aguayo, Nicolás; Báez, Eugenio title: Evans syndrome associated with antiphospholipid antibodies in a patient with SARS-COV-2 infection date: 2020-08-21 journal:
    keywords: antibodies; antiphospholipid; covid-19; infection; patients
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        item: #7141 of 7819
          id: cord-347549-9pijmlpz
      author: Wang, Quan Qiu
       title: COVID-19 risk and outcomes in patients with substance use disorders: analyses from electronic health records in the United States
        date: 2020-09-14
       words: 4300
      flesch: 45
     summary: These results suggest that while comorbidities associated with SUD likely contributed to the increased risk of COVID-19 and to worse outcomes among SUD patients, specific pharmacological effects of drugs of abuse (e.g., opioid induced respiratory depression) as well as behavioral and socioeconomic factors could facilitate COVID-19 infection and increase risk for adverse outcomes. Despite these limitations, this large nationwide database allows us to assess a wide population helping us identify large trends (not necessarily for accurate prevalence estimation) in risks, disparities and outcomes of COVID-19 in SUD patients engaged with healthcare systems.
    keywords: african; covid-19; diagnosis; oud; outcomes; patients; risk; sud
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        item: #7142 of 7819
          id: cord-347553-d7q6u7vj
      author: Criado, Paulo Ricardo
       title: Lessons from dermatology about inflammatory responses in Covid‐19
        date: 2020-07-12
       words: 5074
      flesch: 28
     summary: 30 SARS-CoV may enter human cells via two distinct pathways, dependent on the availability of human cell proteases required for virus activation. Airway and parenchyma immune cells in influenza A(H1N1)pdm09 viral and non-viral diffuse alveolar damage Comparison of Hospitalized Patients With ARDS Caused by COVID-19 and H1N1 Pathological findings of Covid-19 associated with acute respiratory distress syndrome Saldiva Paulo H. N. Lung Pathology in Fatal Novel Human Influenza A (H1N1) Infection Dynamic changes of lymphocyte counts in adult patients with severe pandemic H1N1 influenza A Zhang Shuyang.
    keywords: ace2; activation; cells; coronavirus; cov-2; covid-19; disease; immune; livedoid; patients; protein; sars; syndrome; tissue; tmprss2; vasculopathy
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        item: #7143 of 7819
          id: cord-347602-ab2gv1e5
      author: de Melo, A. C.
       title: Cancer inpatient with COVID-19: a report from the Brazilian National Cancer Institute
        date: 2020-06-29
       words: 3596
      flesch: 49
     summary: Cancer patients with COVID-19 are likely to have a greater risk of complications and death. Particularly in low-and middle-income countries, COVID-19 has brought a heavy burdening to the public health systems and induced new planning and adjustments in the clinical approach to cancer patients 9 . .
    keywords: covid-19; june; license; medrxiv; patients; perpetuity; preprint
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        item: #7144 of 7819
          id: cord-347607-ydbyonbg
      author: Spagnuolo, Rocco
       title: COVID-19 and Inflammatory Bowel Disease: Patient Knowledge and Perceptions in a Single Center Survey
        date: 2020-08-13
       words: 3727
      flesch: 43
     summary: J. Crohn's Colitis 2020 Maintaining the Quality Standards of Care for Inflammatory Bowel Disease Patients During the COVID-19 Pandemic Protection of 318 Inflammatory Bowel Disease Patients from the Outbreak and Rapid Spread of COVID-19 Infection in Wuhan Uneventful course in IBD patients during SARS-CoV-2 outbreak in northern Italy IOIBD Update on COVID19 for Patients with Crohn's Disease and Ulcerative Colitis Withdrawal of immunosuppressant or biologic therapy for patients with quiescent Crohn's disease DOP064 ECCO expert consensus and topical review on treatment exit strategies in inflammatory bowel disease. At date, several ongoing studies evaluate management of IBD patients during pandemic reporting as CD and UC does not increase risk of infection
    keywords: anxiety; covid-19; disease; ibd; knowledge; level; patients
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        item: #7145 of 7819
          id: cord-347631-78h9w2ty
      author: Yun, Debo
       title: Use of lung ultrasound for diagnosis and monitoring of coronavirus disease 2019 pneumonia: A case report
        date: 2020-10-10
       words: 1760
      flesch: 44
     summary: COVID-19 lung ultrasound in emergency department Frequency of abnormalities detected by point-of-care lung ultrasound in symptomatic COVID-19 patients: systematic review and meta-analysis Performance of lung ultrasound in detecting peri-operative atelectasis after general anesthesia Point-of-care lung ultrasound findings in novel coronavirus disease-19 pneumonia: a case report and potential applications during COVID-19 outbreak Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Correlation between chest computed tomography and lung ultrasonography in patients with coronavirus disease 2019 (COVID-19) When the patient recovered from the severe acute respiratory syndrome coronavirus 2 infection, lung ultrasound images showed a normal pleural line with A-lines regularly reverberating.
    keywords: covid-19; lung; lus; patient; ultrasound
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        item: #7146 of 7819
          id: cord-347662-yk3cz0hq
      author: Li, Michael
       title: Tocilizumab in the Management of COVID-19: A Preliminary Report
        date: 2020-11-09
       words: 3302
      flesch: 35
     summary: For ICU patients, TCZ treatment was not significantly correlated with mortality (p = 0.2344). Interestingly, Tocilizumab was not associated with increased mortality in ICU patients, perhaps because of the severity of the condition and duration of disease.
    keywords: covid-19; icu; mortality; patients; tocilizumab; treatment; ventilation
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        item: #7147 of 7819
          id: cord-347675-kgx920dn
      author: Audrey, Fresse
       title: Spontaneous reported cardiotoxicity induced by lopinavir/ritonavir in COVID-19. An alleged past-resolved problem
        date: 2020-10-16
       words: 3983
      flesch: 41
     summary: Spontaneous notifications of cardiac adverse drug reactions reported to the national Pharmacovigilance Network were collected for 8 weeks since March 1st 2020. Atomistic Insights into the Inhibitory Mechanisms Lopinavir/ritonavir: A rapid review of effectiveness in COVID-19 Lopinavir/ritonavir in the treatment of HIV-1 infection: a review Transient cardiac arrhythmias related to lopinavir/ritonavir in two patients with HIV infection Bloqueo auriculoventricular completo en paciente tratado con lopinavir/ritonavir Serious Bradyarrhythmia That Was Possibly Induced by Lopinavir-Ritonavir in 2 Patients with Acquired Immunodeficiency Syndrome A sudden cardiac death induced by sildenafil and sexual activity in an HIV patient with drug interaction, cardiac early repolarization, and arrhythmogenic right ventricular cardiomyopathy Extreme bradycardia due to multiple drug-drug interactions in a patient with HIV post-exposure prophylaxis containing lopinavir-ritonavir Sick sinus syndrome possibly due to lopinavir-ritonavir: report of two cases Bradycardia-tachycardia syndrome induced by lopinavir-ritonavir in a patient with AIDS An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel Blockade of HERG channels by HIV protease inhibitors, The Lancet Cardiac K+ channels and drug-acquired long QT syndrome Boosted protease inhibitors and the electrocardiographic measures of QT and PR durations Electrocardiogram Abnormalities with Atazanavir and Lopinavir/Ritonavir Evaluation of the impact of lopinavir/ritonavir (LPV/r) and ritonavir (RTV) on QTcF: results of a thorough QT study COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options Hypokalemia and Clinical Implications in Patients with Coronavirus Disease Off-label use of hydroxychloroquine, azithromycin, lopinavirritonavir and chloroquine in COVID-19: A survey of cardiac adverse drug reactions by the French Network of Pharmacovigilance Centers Imputabilité des effets inattendus ou toxiques des médicaments: actualisation de la méthode utilisée en France Causality assessment in pharmacovigilance: The French method and its successive updates An Update on Therapeutic Drug Monitoring for Antiretroviral Drugs Determination and Interpretation of the QT Interval AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society.
    keywords: adrs; cardiac; cases; covid-19; drug; lopinavir; lpv; qtc; ritonavir
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        item: #7148 of 7819
          id: cord-347684-qzswojwp
      author: Majumder, Ranabir
       title: Screening of plant-based natural compounds as a potential COVID-19 main protease inhibitor: an in silico docking and molecular dynamics simulation approach
        date: 2020-09-08
       words: 3823
      flesch: 37
     summary: All the small molecules have been docked at COVID-19 M pro inhibition site by Autodock vina (Trott & Olson, 2009 ) using UCSF Chimera gui. We have found that Rutin (-164.299 þ/-38.698 kJ/mol) has a lower binding affinity towards COVID-19 M pro inhibition site as compared to co-crystal ligand inhibitor N3.
    keywords: binding; compounds; covid-19; crystal; energy; inhibitor; ligand; receptor; site
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        item: #7149 of 7819
          id: cord-347691-ia2i8svg
      author: Larici, Anna Rita
       title: Multimodality imaging of COVID-19 pneumonia: from diagnosis to follow-up. A comprehensive review
        date: 2020-08-17
       words: 7459
      flesch: 31
     summary: A study of 302 patients from Italy Association between initial chest CT or clinical features and clinical course in patients with coronavirus disease 2019 pneumonia CT quantification of pneumonia lesions in early days predicts progression to severe illness in a cohort of COVID-19 patients Intensive care risk estimation in COVID-19 pneumonia based on clinical and imaging parameters: experiences from the Munich cohort Multicenter cohort study demonstrates more consolidation in upper lungs on initial CT increases the risk of adverse clinical outcome in COVID-19 patients Well-aerated Lung on Admitting Chest CT to Predict Adverse Outcome in COVID-19 Pneumonia COVID-19 patients and the radiology departmentadvice from the European Society of Radiology (ESR) and the European Society of Thoracic Imaging (ESTI) CT in Coronavirus Disease 2019 (COVID-19): A Systematic Review of Chest CT Findings in 4410 Adult Patients CT Imaging Features of 4121 Patients With COVID-19: A Meta-Analysis Pulmonary Pathology of Early-Phase 2019 Novel Coronavirus (COVID-19) Pneumonia in Two Patients With Lung Cancer Histopathologic Changes and SARS-CoV-2 Immunostaining in the Lung of a Patient With COVID-19 Pathological findings of COVID-19 associated with acute respiratory distress syndrome High expression of ACE2receptor of 2019-nCoV on the epithelial cells of oral mucosa Angiotensin-converting enzyme 2 protects from severe acute lung failure The Pathogenesis and Treatment of the 'Cytokine Storm' in COVID-19 Endothelial cell infection and endotheliitis in COVID-19 Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: A report of five cases Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia High-resolution Computed Tomography Findings of Acute Respiratory Distress Syndrome, Acute Interstitial Pneumonia, and Acute Exacerbation of Idiopathic Pulmonary Fibrosis Time Course of Lung Changes at Chest CT During Recovery From 2019 Novel Coronavirus (COVID-19) Clinical implications High Incidence of Barotrauma in Patients With COVID-19 Infection on Invasive Mechanical Ventilation Acute pulmonary embolism and COVID-19 Pulmonary embolism in patients with COVID-19 pneumonia Acute pulmonary embolism associated with COVID-19 pneumonia detected by pulmonary CT angiography Pulmonary embolism in COVID-19 patients: awareness of an increased prevalence Pulmonary Vascular Manifestations of COVID-19 Radiology:
    keywords: acute; cases; chest; covid-19; diagnosis; disease; findings; hrct; imaging; lung; opacities; patients; pneumonia
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        item: #7150 of 7819
          id: cord-347697-uz0i6wfp
      author: McLean, Ross C.
       title: A single-centre observational cohort study to evaluate volume and severity of emergency general surgery admissions during the COVID-19 pandemic: is there a “lockdown” effect?
        date: 2020-09-12
       words: 3908
      flesch: 39
     summary: [40] [41] in these patients are J o u r n a l P r e -p r o o f essential, particularly if there are concerns of ischaemic bowel or perforations as these are significant predictors of mortality for emergency general surgical patients. However, the 'gatekeeper' effect is likely to be minimal in this study as there were no significant differences in management of surgical patients before or after lockdown, and our findings are replicated in different surgical specialities and in different healthcare systems
    keywords: covid-19; emergency; lockdown; mortality; patients; study; surgical
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        item: #7151 of 7819
          id: cord-347718-qctii42h
      author: Sgura, Fabio Alfredo
       title: Complicated myocardial infarction in a 99-year-old lady in the era of COVID-19 pandemic: from the need to rule out coronavirus infection to emergency percutaneous coronary angioplasty
        date: 2020-05-13
       words: 1967
      flesch: 30
     summary: During the worldwide emergency induced by COVID-19 infection, physicians are continuously requested to apply methods for containing and treating this infection, but they also need to maintain an adequate standard of care for the other diseases, especially for elderly patients who are vulnerable to any major illness, including coronary artery disease. Although acute coronary syndrome (specifically non-STsegment elevation myocardial infarction) was considered as the most probable diagnosis, watchful waiting was initially applied, taking into account patient's history and the very advanced age and, above all, the need to rule out COVID-19 infection in view of the presence of fever, cough and the ongoing COVID-19 pandemic.
    keywords: care; covid-19; infarction; patients
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        item: #7152 of 7819
          id: cord-347737-guldy3cq
      author: Dalan, Rinkoo
       title: Metformin, Neutrophils and COVID-19 Infection
        date: 2020-05-22
       words: 699
      flesch: 28
     summary: Until we have real world data on the effects of metformin use in COVID-19 patients with diabetes, no conclusive judgement with regards to its overall usefulness, neutral or detrimental effects can be made. In an autopsy study of COVID-19 patients, neutrophil infiltration in pulmonary capillaries, extravasation of neutrophils into the alveolar space, and neutrophilic mucositis has been reported [7] .
    keywords: covid-19; metformin; neutrophil
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        item: #7153 of 7819
          id: cord-347752-2ejnva4u
      author: Mrabti, Hind
       title: Cancer management challenge in a developing country in COVID-19 pandemic: reflection of a group of Moroccan oncologists
        date: 2020-06-25
       words: 4586
      flesch: 35
     summary: The official French guidelines to protect patients with cancer against SARS-CoV-2 infection guidelines for cancer patients during COVID-19 pandemic Management of ovarian cancer during the COVID-19 pandemic Caring for patients with cancer during the COVID-19 outbreak in Italy The Lebanese Society of Medical Oncology (LSMO) statement on the care of patients with cancer during the COVID-19 pandemic • Lebanese guidelines of cancer management during COVID-19 pandemic Preparing African anticancer centres in the COVID-19 outbreak Impact of cancer on Muslim patients in Morocco Factors associated with the time to first palliative care consultation in Lebanese cancer patients Caring for patients with cancer in the COVID-19 era European cancer centers management during COVID-19 pandemic COVID-19 and treatment with NSAIDs and corticosteroids: should we be limiting their use in the clinical setting Continued treatment effect of zoledronic acid dosing every 12 vs 4 weeks in women with breast cancer metastatic to bone Controversies about COVID-19 and anticancer treatment with immune checkpoint inhibitors Managing oncology services during a major coronavirus outbreak: lessons from the Saudi Arabia experience •• Describes oncology department management during COVID-19 pandemic The Moroccan expert panel of oncologists, proposed these recommendations for the management of cancer patients which had to take into account several parameters: • Keep cancer patients away from the risk of contracting the coronavirus: which could be dangerous for them but also for their family since they are immunocompromised and are more likely to contract it and therefore transmit it to those around them; • Take into account the short-term prognosis of the disease, especially for metastatic diseases; • Take into account the long-term prognosis for patients treated in a curative situation; • Protect healthcare workers, families of cancer patients.
    keywords: cancer; care; covid-19; health; management; patients; risk; situation; treatment
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        item: #7154 of 7819
          id: cord-347775-hidb8q1u
      author: Karatza, Eleni
       title: Optimization of hydroxychloroquine dosing scheme based on COVID-19 patients’ characteristics: a review of the literature and simulations
        date: 2020-09-30
       words: 5972
      flesch: 40
     summary: al., 2020; Liu et al., 2020b; Yao et al., 2020) , there is currently a need to rationalize the administered dosing schemes in order to maximize the efficacy and safety of HCQ in patients with COVID-19. Therefore, blood levels should ideally reach 1500 ng/ml during the first days upon diagnosis, especially in severe cases with high viral load, and be kept above 500 ng/ ml for the following days (Durcan et al., 2015; Liu et al., 2020b; Yao et al., 2020) .
    keywords: clearance; covid-19; dose; dosing; et al; hcq; hydroxychloroquine; patients; treatment
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        item: #7155 of 7819
          id: cord-347778-b2ufs25y
      author: Ebigbo, Alanna
       title: Impact of the COVID-19 pandemic on gastrointestinal endoscopy in Africa
        date: 2020-08-07
       words: 2117
      flesch: 44
     summary: key: cord-347778-b2ufs25y authors: Ebigbo, Alanna; Karstensen, John Gásdal; Bhat, Purnima; Ijoma, Uchenna; Osuagwu, Chukwuemeka; Desalegn, Hailemichael; Oyeleke, Ganiyat K.; Gebru, Rezene B.; Guy, Claire; Antonelli, Giulio; Vilmann, Peter; Aabakken, Lars; Hassan, Cesare title: Impact of the COVID-19 pandemic on gastrointestinal endoscopy in Africa date: 2020-08-07 journal: As with all other fields of medical practice, gastrointestinal endoscopy has been impacted by the COVID-19 pandemic.
    keywords: africa; covid-19; endoscopy; impact; pandemic
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        item: #7156 of 7819
          id: cord-347780-jrbiww9j
      author: FAYSSOIL, Abdallah
       title: The Right Ventricle in COVID-19 Patients
        date: 2020-06-09
       words: 328
      flesch: 29
     summary: In addition, COVID-19 patients disclose a hyper coagulate state avec a significant incidence of pulmonary thrombotic complications, aggravated the RV afterload is associated with excess mortality in ARDS (4). Finally, the RV function, measured by the tricuspid annular plane systolic excursion (TAPSE), the right ventricular fractional area change (RVFAC) and the right ventricular longitudinal strain, is a significant predictive factor of mortality in COVID-19 infected patients (6) .
    keywords: covid-19
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        item: #7157 of 7819
          id: cord-347789-ou4unny6
      author: Croll, Leah
       title: The psychosocial implications of COVID-19 for a neurology program in a pandemic epicenter
        date: 2020-07-14
       words: 3482
      flesch: 44
     summary: This report outlines the psychosocial concerns of neurology faculty and housestaff and the multifaceted support services that our department and institution are offering in response. This report outlines the psychosocial concerns of neurology faculty and housestaff and the multifaceted support services that our department and institution are offering in response.
    keywords: covid-19; department; faculty; housestaff; pandemic
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        item: #7158 of 7819
          id: cord-347813-9vfwl7c0
      author: Jackson, M. L.
       title: Low-Impact Social Distancing Interventions to Mitigate Local Epidemics of SARS-CoV-2
        date: 2020-07-02
       words: 3785
      flesch: 42
     summary: May 2020, in the presence of social distancing interventions as actually implemented in King County. Results Individual interventions are not expected to have a large impact on COVID-19 hospitalizations.
    keywords: cov-2; covid-19; hospital; interventions; model; preprint; sars
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        item: #7159 of 7819
          id: cord-347816-e2xkzps9
      author: Wesemann, U.
       title: Influence of COVID-19 on general stress and posttraumatic stress symptoms among hospitalized high-risk patients
        date: 2020-08-14
       words: 1165
      flesch: 49
     summary: key: cord-347816-e2xkzps9 authors: Wesemann, U.; Hadjamu, N.; Willmund, G.; Dolff, S.; Vonderlin, N.; Wakili, R.; Vogel, J.; Rassaf, T.; Siebermair, J. title: Influence of COVID-19 on general stress and posttraumatic stress symptoms among hospitalized high-risk patients date: 2020-08-14 journal: Psychological medicine DOI: 10.1017/s0033291720003165 sha: doc_id: 347816 cord_uid: e2xkzps9 nan To the Editor: A recently published study found a 96.2% prevalence rate for significant posttraumatic stress symptoms in quarantined patients diagnosed with COVID-19 (Bo et al., 2020) . Thereby, the rates for posttraumatic stress disorder (PTSD) in COVID-19 affected patients appear higher when compared to PTSD rates in the general population or in emergency service staff after terrorist attacks (11% to 25%; Berninger et al. 2010; Brackbill, Hadler, DiGrande, Ekenga, & Farfel, 2009; Schlenger et al. 2002; Wesemann et al., 2018b; Wesemann, Mahnke, Polk, & Willmund, 2020) .
    keywords: covid-19; patients; stress
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        item: #7160 of 7819
          id: cord-347818-93ixqyfp
      author: Hojyo, Shintaro
       title: How COVID-19 induces cytokine storm with high mortality
        date: 2020-10-01
       words: 4532
      flesch: 33
     summary: Coagulation and inflammation cross-talking Complex immune dysregulation in COVID-19 patients with severe respiratory failure Inhibition of NF-kappaB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival Chimeric antigen receptor T-cell therapy -assessment and management of toxicities Randomized trial of tocilizumab in systemic juvenile idiopathic arthritis Addition of interleukin-6 inhibition with tocilizumab to standard graftversus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial Interleukin 6 receptor inhibitor tocilizumab suppresses cytokine expression, inflammasome activation and phagocytosis in a cell model of sepsis Tocilizumab treatment in COVID-19: a single center experience Effective treatment of severe COVID-19 patients with tocilizumab Tocilizumab for the treatment of severe COVID-19 pneumonia with hyperinflammatory syndrome and acute respiratory failure: a single center study of 100 patients in Brescia Sarilumab: a review in moderate to severe rheumatoid arthritis Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review Baricitinib: the second FDA-approved JAK inhibitor for the treatment of rheumatoid arthritis Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Not applicable. We herein review the pathogenic mechanism and potential therapeutic targets of ARDS in COVID-19 patients.
    keywords: ace2; activation; cells; coronavirus; cov-2; covid-19; cytokine; il-6; patients; sars
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        item: #7161 of 7819
          id: cord-347834-skj40pmi
      author: Ruggiero, Antonio
       title: Diagnosis of COVID‐19 infection in children: less nasopharyngeal swabs, more saliva
        date: 2020-06-07
       words: 658
      flesch: 47
     summary: The conclusion was that COVID-19 infection can occur in children, but they seemed to have a lower incidence as well as a milder disease course and better prognosis than adults. All rights reserved To date, none of these theories fully explain the low incidence of COVID-19 infection in children.
    keywords: children; covid-19
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        item: #7162 of 7819
          id: cord-347835-6zx9g2io
      author: Ashraf, Said
       title: Acute coronary syndrome in the time of the COVID-19 pandemic
        date: 2020-06-07
       words: 1820
      flesch: 46
     summary: 6 A mixed model analysing data comparing before COVID-19 time (1 January 2019 to 29 February 2020) with after COVID-19 (1-31 March 2020) displayed a 38% reduction in STEMI activations. There was a disproportionately greater decrease in STEMI reductions for women, 41.2%, than for men, 25.4%.
    keywords: covid-19; pandemic; patients; reduction; stemi
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        item: #7163 of 7819
          id: cord-347870-lnwjr9be
      author: Tsui, Edmund
       title: Using Social Media to Disseminate Ophthalmic Information During the #COVID19 Pandemic
        date: 2020-06-02
       words: 1053
      flesch: 35
     summary: As cases of COVID-19 spread worldwide, so did sharing of experiences and 31 research via social media in efforts to mitigate the disease spread and to increase awareness. 4,5 With this perspective, we outline how social media has 40 become increasingly integrated into our emergency response as a field.
    keywords: covid-19; media; pandemic
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        item: #7164 of 7819
          id: cord-347874-cmgd5rqt
      author: de Miguel Beriain, Iñigo
       title: Immunity passports, fundamental rights and public health hazards: a reply to Brown et al
        date: 2020-09-09
       words: 1964
      flesch: 52
     summary: key: cord-347874-cmgd5rqt authors: de Miguel Beriain, Iñigo; Rueda, Jon title: Immunity passports, fundamental rights and public health hazards: a reply to Brown et al date: 2020-09-09 journal: J Med Ethics DOI: 10.1136/medethics-2020-106814 sha: doc_id: 347874 cord_uid: cmgd5rqt In their recent article, Brown et al analyse several ethical aspects around immunity passports and put forward some recommendations for implementing them. Vaccine certificates will de facto generate a sort of immunity passport.
    keywords: covid-19; health; immunity; rights
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        item: #7165 of 7819
          id: cord-347884-zpzncgiv
      author: Galimberti, Andrea
       title: Rethinking Urban and Food Policies to Improve Citizens Safety After COVID-19 Pandemic
        date: 2020-10-08
       words: 5477
      flesch: 29
     summary: To shed light on this issue, we brought together a faculty group involving experts in environment and biodiversity, food safety, human nutrition, and behavior, bioprospecting, as well as medical doctors having a deep knowledge of the complex historical relationship between humanity and vector-borne infections. Definitely, some priority issues should be addressed to achieve these goals, such as global efforts to increase food safety and security, which would benefit from urban and peri-urban agriculture enhancement, smallholder food producers support, and ecosystem services and local biodiversity maintenance.
    keywords: approach; biodiversity; coronavirus; covid-19; diseases; environment; food; health; human; nutrition; pandemic; safety; spread; urban
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        item: #7166 of 7819
          id: cord-347890-kx5vka0o
      author: Fan, Qian
       title: Association Between ABO Blood Group System and COVID-19 Susceptibility in Wuhan
        date: 2020-07-21
       words: 3783
      flesch: 43
     summary: This work was supported by the Chinese Universities Scientific Fund (No. 2042018kf0136) to QF and Scientific Research Project of Hubei Provincial Health Committee (WJ2019M208) to FZ. Variation in the host ABO blood group may be associated with susceptibility to hepatitis C virus infection Comparative genetic analysis of the novel coronavirus (2019-nCoV/SARS-CoV-2) receptor ACE2 in different populations Association between ABO blood groups and Helicobacter pylori infection: a meta-analysis A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study ABO blood group system and the coronary artery disease: an updated systematic review and meta-analysis ABO blood group and susceptibility to severe acute respiratory syndrome Blood Groups in Infection and Host Susceptibility Association of ABO blood group and P. falciparum malaria related outcomes: a cross-sectional study in Ethiopia ABO blood grouping in Egyptian children with rotavirus gastroenteritis Human microbiota, blood group antigens, and disease COVID-19 and ABO blood group: another viewpoint Genetically determined ABO blood group and its associations with health and disease Inhibition of the interaction between the SARS-CoV spike protein and its cellular receptor by anti-histo-blood group antibodies Histo-blood group antigens as mediators of infections Clinical features of patients infected with 2019 novel coronavirus in Wuhan ABO blood groups and hepatitis B virus infection: a systematic review and meta-analysis Secretor and salivary ABO blood group antigen status predict rotavirus vaccine take in infants Association between ABO blood groups and risk of SARS-CoV-2 pneumonia Animal origins of the severe acute respiratory syndrome coronavirus: insight from ACE2-S-protein interactions ABO blood group-associated susceptibility to norovirus infection: a systematic review and meta-analysis Distribution of ABO/Rh blood groups and their association with hepatitis B virus infection in 3.8 million Chinese adults: a population-based cross-sectional study Beyond immunohaematology: the role of the ABO blood group in human diseases A genome-wide association study identifies protein quantitative trait loci (pQTLs) Association of ABO and Rh blood groups to blood-borne infections among blood donors in Tehran-Iran Blood group AB is associated with severe forms of dengue virus infection HIV-1 incorporates ABO histo-blood group antigens that sensitize virions to complement-mediated inactivation tructural Constraints on Human Norovirus Binding to Histo The ABO blood group system revisited: a review and update Potent binding of 2019 novel coronavirus spike protein by a SARS coronavirusspecific human monoclonal antibody Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China ABO genotype and risk of thrombotic events and hemorrhagic stroke Pancreatic cancer risk and ABO blood group alleles: results from the pancreatic cancer cohort consortium Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Compensation of ACE2 Function for Possible Clinical Management of 2019-nCoV-Induced Acute Lung Injury Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: As shown in Table 2 , we performed a combined association analysis between ABO blood group and COVID-19, which showed a statistically significant difference in COVID-19 infection among those with blood type A (P = 0.04, OR = 1.33, 95% CI = 1.02-1.73) but not blood types B, AB or O (P = 0.48, OR = 0.90, 95% CI = 0.66-1.23; P=0.61, OR = 0.88, 95% CI = 0.53-1.46; and P = 0.23, OR = 0.82, 95% CI = 0.58-1.15, respectively).
    keywords: abo; analysis; blood; covid-19; group; type
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        item: #7167 of 7819
          id: cord-347895-z9a54f6g
      author: Gaibazzi, N.
       title: Lung disease severity, Coronary Artery Calcium, Coronary inflammation and Mortality in Coronavirus Disease 2019.
        date: 2020-05-06
       words: 4060
      flesch: 39
     summary: https://doi.org/10.1101/2020.05.01.20087114 doi: medRxiv preprint in-hospital death, we may reasonably conclude that pre-existent (known or unknown) CAD has no or limited role in worsening the outcome of COVID-19 patients. The finding that a higher coronary inflammation status in COVID-19 patients is associated with mortality is instead a novel finding and may shed some light on the possible mechanisms responsible for the frequently-found myocardial injury, associated with higher mortality in COVID-19 patients.(4-7) However, the current study did not address the incidence of myocardial injury (cardiac troponins were not routinely measured in our COVID-19 cohort), so that while we can affirm that coronary inflammation is associated with in-hospital death, we cannot speculate on the relation between coronary inflammation and myocardial injury.
    keywords: coronary; covid-19; hrct; license; medrxiv; patients; preprint; version
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        item: #7168 of 7819
          id: cord-347898-appzi43a
      author: Hu, Zeming
       title: The Status of Psychological Issues Among Frontline Health Workers Confronting the Coronavirus Disease 2019 Pandemic
        date: 2020-06-05
       words: 1722
      flesch: 36
     summary: Second, social support, including online services and guidelines provided by organizations, should be utilized to timely, effectively, and efficiently mitigate the psychological impacts among health workers. Mechanisms for effective communication should be put in place to allow health care workers update their leaders about their working conditions and schedule for break from work (16) .
    keywords: covid-19; health; healthcare; workers
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        item: #7169 of 7819
          id: cord-347900-nzd15vab
      author: Iyengar, Karthikeyan P.
       title: Tuberculosis and COVID-19 in India-double trouble!
        date: 2020-07-17
       words: 388
      flesch: 39
     summary: • Telemedicine has definite role in monitoring, contact tracing and remote management of TB patients and COVID-19 disease in the current senario. . Smartphone technology applications can be expanded to play a key role in assessment, monitoring, contact tracing and remote management of TB patients as it is being undertaken for COVID-19 disease in the current pandemic [4] .
    keywords: covid-19
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        item: #7170 of 7819
          id: cord-347906-3ehsg8oi
      author: Zhang, Zizhen
       title: Dynamics of COVID-19 mathematical model with stochastic perturbation
        date: 2020-08-28
       words: 1776
      flesch: 53
     summary: Adv Differ Equ DOI: 10.1186/s13662-020-02909-1 sha: doc_id: 347906 cord_uid: 3ehsg8oi Acknowledging many effects on humans, which are ignored in deterministic models for COVID-19, in this paper, we consider stochastic mathematical model for COVID-19. key: cord-347906-3ehsg8oi authors: Zhang, Zizhen; Zeb, Anwar; Hussain, Sultan; Alzahrani, Ebraheem title: Dynamics of COVID-19 mathematical model with stochastic perturbation date: 2020-08-28 journal:
    keywords: coronavirus; covid-19; epidemic; model; stochastic
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        item: #7171 of 7819
          id: cord-347916-9suvf3ln
      author: Kong, Man
       title: Higher level of neutrophil-to-lymphocyte is associated with severe COVID-19
        date: 2020-07-09
       words: 3305
      flesch: 46
     summary: Early identification of risk factors for severe patients is vital to afford appropriate supportive care or access to ICU if necessary. A study (n = 61) recently reported that NLR was the most useful factor affecting the incidence of severe COVID-19 and indicated the incidence of severe illness with NLR ≥ 3.13
    keywords: cases; cells; covid-19; group; nlr; patients; study
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        item: #7172 of 7819
          id: cord-347926-63w578b2
      author: Ruan, Pei-sen
       title: COVID-19 in Children: Clinical Characteristics and Follow-Up Study
        date: 2020-09-03
       words: 1206
      flesch: 46
     summary: Many researchers had reported that varieties of cases of recovered COVID-19 pediatric patients had positive RT-PCR test again. At present, pediatric patients have been reported all over the world, mainly asymptomatic and mild infections.
    keywords: children; coronavirus; covid-19; patients
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        item: #7173 of 7819
          id: cord-347935-jfx9037u
      author: Valdivia, Andrés Reyes
       title: Adapting vascular surgery practice to the current COVID-19 era at a tertiary academic center in Madrid.
        date: 2020-06-04
       words: 1984
      flesch: 47
     summary: As described 209 previously, COVID-19 patients can associate a pro-coagulant state which can lead 210 either to deep vein thrombosis (DVT) and /or peripheral arterial thrombosis. Pertaining DVT, a previous description of 23% incidence 213 for COVID-19 patients in ICU and 8% not requiring ventilator demonstrated the 214 importance of such situation in these patients.
    keywords: covid-19; patients; practice; vascular
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        item: #7174 of 7819
          id: cord-347955-bud745if
      author: Jenelius, Erik
       title: Impacts of COVID-19 on public transport ridership in Sweden: Analysis of ticket validations, sales and passenger counts
        date: 2020-11-30
       words: 5038
      flesch: 59
     summary: key: cord-347955-bud745if authors: Jenelius, Erik; Cebecauer, Matej title: Impacts of COVID-19 on public transport ridership in Sweden: Analysis of ticket validations, sales and passenger counts date: 2020-11-30 journal: Transportation Research Interdisciplinary Perspectives DOI: 10.1016/j.trip.2020.100242 sha: doc_id: 347955 cord_uid: bud745if The paper analyses the impacts of COVID-19 on daily public transport ridership in the three most populated regions of Sweden (Stockholm, Västra Götaland and Skåne) during spring 2020. The decrease in public transport ridership (40%–60% across regions) was severe compared with other transport modes.
    keywords: covid-19; data; number; period; public; ridership; stockholm; tickets; transport; trips
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        item: #7175 of 7819
          id: cord-347960-vl5zhxyh
      author: Giallonardo, Vincenzo
       title: The Impact of Quarantine and Physical Distancing Following COVID-19 on Mental Health: Study Protocol of a Multicentric Italian Population Trial
        date: 2020-06-05
       words: 6335
      flesch: 34
     summary: The analytic plan will include: 1) data cleaning of the online dataset and replacement of missing values; 2) descriptive statistics of the general characteristics of the recruited sample, in terms of levels of depressive and anxiety symptoms, posttraumatic and stress-related symptoms, insomnia, satisfaction with life, suicidal ideation, hopelessness, post-traumatic growth, resilience, coping strategies, and social support; 3) sub-groups analyses based on the level of exposure to the pandemic (i.e., COVID-19 quarantine group vs. COVID-19+ patients group vs. COVID-19 healthcare staff group vs. COVID-19 mental health group); 4) calculation of a propensity score, in order to adjust our findings for the likelihood of being exposed to the pandemic and to the quarantine (48, 49) . In fact, the analyses will be run according to the four subgroups of respondents: the general population not directly affected by the virus (COVID-19 quarantine group); people who have had a direct or indirect contact with the virus (COVID-19+ patients group); those working in health care units as first or second-line staff (COVID-19 healthcare staff group); people with mental health problems, independently from the contact with the virus (COVID-19 mental health).
    keywords: covid-19; group; health; impact; pandemic; people; population; post; quarantine; stress; study; symptoms
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        item: #7176 of 7819
          id: cord-347968-jhnr8k3j
      author: Herrera, David
       title: Is the oral cavity relevant in SARS-CoV-2 pandemic?
        date: 2020-06-23
       words: 3394
      flesch: 27
     summary: This positive impact may specifically be even more relevant in the context of the clinical practice of dentistry [16] , since due to the frequent generation of aerosols, the associated risk of virus transmission may be enhanced during the different dental procedures [11, 17] . Oral viral load of SARS-CoV-2 has been associated with the severity of COVID-19, and thus, a reduction in the oral viral load could be associated with a decrease in the severity of the condition.
    keywords: cov-2; covid-19; iodine; oral; povidone; sars; transmission; virus
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        item: #7177 of 7819
          id: cord-347969-2sdwwuu5
      author: Grunau, Brian
       title: Bystanders are less willing to resuscitate out-of-hospital cardiac arrest victims during the COVID-19 pandemic
        date: 2020-10-05
       words: 2986
      flesch: 46
     summary: Although most previous surveys of bystander willingness to perform CPR have asked binary questions of are you willing to intervene we asked respondents to grade their willingness on a scale, a technique that has been previously described and validated. One study examining bystander willingness to perform CPR prior to the COVID-19 pandemic demonstrated that men were more likely to intervene, 9 however another study detected no differences between sexes.
    keywords: bystander; covid-19; cpr; pandemic; survey; willingness
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        item: #7178 of 7819
          id: cord-347982-omxcdiwt
      author: Basso, Fernanda Gisele
       title: Cooperative efforts on developing vaccines and therapies for COVID-19 Cooperative efforts for COVID-19
        date: 2020-09-06
       words: 3436
      flesch: 30
     summary: Social Network Analysis technique was used to build cooperation networks and apply metrics that characterize these connections. Organizations which are in cooperation networks that are more heterogeneous tend to be associated with better economic performance [8] .
    keywords: cooperation; covid-19; development; innovation; networks; organizations; partnerships
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        item: #7179 of 7819
          id: cord-347984-iqsbrw88
      author: Shi, Feng
       title: Review of Artificial Intelligence Techniques in Imaging Data Acquisition, Segmentation and Diagnosis for COVID-19
        date: 2020-04-06
       words: 6949
      flesch: 47
     summary: With this limited number of COVID-19 images, it is insufficient to evaluate the robustness of the methods and also poses questions to the generalizability with respect to applications in other clinical centers. Reverse Transcription-Polymerase Chain Reaction (RT-PCR) test serves as the gold standard of confirming COVID-19 patients [4] .
    keywords: chest; covid-19; images; imaging; lung; patients; pneumonia; ray; segmentation
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        item: #7180 of 7819
          id: cord-348022-nt5omngy
      author: Pavlidis, Pollyanna
       title: Clinical guidelines for caring for women with COVID-19 during pregnancy, childbirth and the immediate postpartum period
        date: 2020-11-03
       words: 5043
      flesch: 41
     summary: Living guideline recommendations Developing and applying a 'living guidelines' approach to WHO recommendations on maternal and perinatal health Bringing stroke clinical guidelines to life BOXES Box 1: Priority topics Provision of maternal health care during the COVID-19 pandemic Not applicable. COVID-19 Public hospital visitor guidelines.
    keywords: birth; consensus; coronavirus; covid-19; disease; guidelines; health; recommendations; women
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        item: #7181 of 7819
          id: cord-348024-n8wn4och
      author: Lei, Fang
       title: Longitudinal association between markers of liver injury and mortality in COVID‐19 in China
        date: 2020-05-02
       words: 3207
      flesch: 39
     summary: Medical history comprised coexistence of chronic obstructive pulmonary disease (COPD), type 2 diabetes mellitus (T2DM), hypertension, coronary heart disease, cerebrovascular disease, chronic liver disease, CKD, cancer, and autoimmune diseases. A total of 81 (1.4%) patients reported chronic liver disease.
    keywords: alt; ast; covid-19; disease; injury; levels; liver; mortality; patients
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        item: #7182 of 7819
          id: cord-348026-t1jkeu3d
      author: Ruhnke, Gregory W.
       title: Physician Supply During the Coronavirus Disease 2019 (COVID-19) Crisis: the Role of Hazard Pay
        date: 2020-06-10
       words: 1278
      flesch: 31
     summary: These include subtle coercion without compensation, forcing physicians to work outside their usual scope of practice, or utilizing the services of older physicians, whose work-related exposure may markedly increase the burden on an alreadyoverwhelmed health care system. The options for rapidly increasing the physician labor supply include physicians working outside their typical area of practice (e.g., shifting their site of work to the emergency room or inpatient units), retired physicians re-entering the workforce, substitution through alternative advanced practice providers (such as nurse practitioners and physician assistants), and early graduation of medical students.
    keywords: covid-19; hazard; pay; physicians
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        item: #7183 of 7819
          id: cord-348039-kl1a0au3
      author: Majowicz, S. E.
       title: What might the future bring? COVID-19 planning considerations for faculty and universities
        date: 2020-04-29
       words: 2898
      flesch: 35
     summary: COVID-19 planning considerations for faculty and universities date: 2020-04-29 journal: Epidemiol Infect DOI: 10.1017/s0950268820000898 sha: doc_id: 348039 cord_uid: kl1a0au3 This paper applies a scenario planning approach, to outline some current uncertainties related to COVID-19 and what they might mean for plausible futures for which we should prepare, and to identify factors that we as individual faculty members and university institutions should be considering now, when planning for the future under COVID-19. This paper applies a similar approach, in order to: (a) outline some current uncertainties related to COVID-19, and what they might mean for plausible futures for which we should prepare; and (b) list factors that we as individual faculty members and university institutions should be considering now, when planning for the future under COVID-19.
    keywords: covid-19; e.g.; factors; future; pandemic; planning
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        item: #7184 of 7819
          id: cord-348051-o1hxoasp
      author: Upadhyaya, Gaurav K.
       title: Challenges and strategies in management of osteoporosis and fragility fracture care during COVID-19 pandemic
        date: 2020-06-02
       words: 3392
      flesch: 40
     summary: Traditional radiology can possibly diagnose osteoporosis fractures in the most commonly involved sites (spine, pelvis, distal radius, proximal femur and humerus,). Further these patients require short hospitalization for observation during IV infusion which will be difficult in current scenario when the hospitals are flooded with COVID-19 patients and the transportation is limited in many areas.
    keywords: bone; covid-19; fractures; fragility; hip; management; osteoporosis; pandemic; patients; risk
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        item: #7185 of 7819
          id: cord-348053-s0ijzyaq
      author: Mueller, Alisa A.
       title: Inflammatory biomarker trends predict respiratory decline in COVID-19 patients
        date: 2020-10-29
       words: 3734
      flesch: 41
     summary: Our work suggests that close, serial monitoring of early CRP values may aid clinical prognostication and consideration of immunomodulatory therapy in COVID-19 patients. Prior studies typically stratify COVID-19 patients into either noncritical or critical categories and do not distinguish patients that were critically ill at admission versus those patients that initially had non-critical illness and then deteriorated.
    keywords: admission; covid-19; crp; hospital; levels; patients; study
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        item: #7186 of 7819
          id: cord-348056-kx9wvw8c
      author: Goh, H. P.
       title: Risk factors affecting COVID-19 case fatality rate: A quantitative analysis of top 50 affected countries
        date: 2020-05-25
       words: 2458
      flesch: 58
     summary: key: cord-348056-kx9wvw8c authors: Goh, H. P.; Mahari, W. I.; Ahad, N. I.; Chaw, L.; Kifli, N.; Goh, B. H.; Yeoh, S. F.; Ming, L. C. title: Risk factors affecting COVID-19 case fatality rate: A quantitative analysis of top 50 affected countries date: 2020-05-25 journal: nan DOI: 10.1101/2020.05.20.20108449 sha: doc_id: 348056 cord_uid: kx9wvw8c Background: Latest clinical data on treatment on coronavirus disease 2019 (COVID-19) indicated that older patients and those with underlying history of smoking, hypertension or diabetes mellitus might have poorer prognosis of recovery from COVID-19. Apart from addressing risk factors, there are also parameters that 100 may affect the COVID-19 mortality rate such as shortage of staff, lack of medical supply or 101 equipment, insufficient hospital beds and the country's health expenditure.
    keywords: covid-19; license; preprint; risk
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        item: #7187 of 7819
          id: cord-348121-c7jq240j
      author: Tagliabue, Fabio
       title: The “Pandemic” of Disinformation in COVID-19
        date: 2020-08-01
       words: 1515
      flesch: 37
     summary: During the COVID-19 epidemic, misinformation and fake news have represented an important issue generating confusion and insecurity among the population. The general population has, in good faith, taken the information, including fake news, most relevant to their own personal situation and has used it to formulate their own interpretation of the pandemic.
    keywords: covid-19; mass; media; news; pandemic
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        item: #7188 of 7819
          id: cord-348139-bx1rt5ko
      author: Dhamne, Chetan
       title: Comment on: The COVID‐19 pandemic: A rapid global response for children with cancer from SIOP, COG, SIOP‐E, SIOP‐PODC, IPSO, PROS, CCI, and St Jude Global
        date: 2020-07-10
       words: 801
      flesch: 33
     summary: These guidelines helped us to successfully brace for the initial COVID-19 surge, and a brief summary of the first seven cases of childhood cancer from among 59 COVID-19 patients in 5 weeks from the first recorded case seen at our center is included (Table 1) Early advice on managing children with cancer during the COVID-19 pandemic and a call for sharing experiences The COVID-19 PAN-DEMIC: a rapid global response for children with cancer from SIOP Cancer management in India during COVID-19 The Tata Memorial Centre COVID-19 Working Group. 3, 4 Within this larger response, we tailored management of pediatric cancers to meet the twin objectives of retaining hard-fought recent improvements in disease outcomes of largely curable malignancies, 5, 6 while balancing resource constraints from disruption of services, and evolving strategies for the inevitable cancer with COVID-19 patient surge.
    keywords: cancer; covid-19; pandemic
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        item: #7189 of 7819
          id: cord-348155-otcg3lgh
      author: Mahmoud-Elsayed, Hani M.
       title: Echocardiographic Findings in Covid-19 Pneumonia
        date: 2020-05-28
       words: 1493
      flesch: 36
     summary: Indeed, many patients exhibited the McConnell sign (exemplar case, Supplementary Video), which involves severe free wall hypokinesia or akinesia with apical sparing. key: cord-348155-otcg3lgh authors: Mahmoud-Elsayed, Hani M.; Moody, William E.; Bradlow, William M.; Khan-Kheil, Ayisha M.; Hudsmith, Lucy E.; Steeds, Richard P. title: Echocardiographic Findings in Covid-19 Pneumonia date: 2020-05-28 journal: Can J Cardiol DOI: 10.1016/j.cjca.2020.05.030 sha: doc_id: 348155 cord_uid: otcg3lgh The aim of this study was to characterize the echocardiographic phenotype of patients with Covid-19 pneumonia and its relation to biomarkers.
    keywords: covid-19; echocardiography; patients
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        item: #7190 of 7819
          id: cord-348172-q3zcn5pf
      author: Poli, Daniela
       title: Managing anticoagulation in the COVID-19 era between lockdown and reopening phases
        date: 2020-06-08
       words: 1327
      flesch: 31
     summary: Patients on anticoagulant treatment are constantly increasing, with a prevalence of nearly 2% of the total population [1] . Anticoagulation Clinics (ACs) routinely manage thousands of patients taking anticoagulants, either vitamin K antagonists (VKAs), direct oral anticoagulants (DOACs), or parenteral drugs. To view a copy of this licence, visit http://creat iveco mmons .org/licen ses/by/4.0/. FADOI (Federation of Associations of Hospital Doctors on Internal Medicine), SISET (Italian Society for the Study of Haemostasis and Thrombosis) (2017) Italian intersociety consensus on DOAC use in internal medicine The effect of management models on thromboembolic and bleeding rates in anticoagulated patients: an ecological study European Centre for Disease Prevention and Control (2020) Infection prevention and control for COVID-19 in healthcare settingsthird update Lip GYH (2020) cardiovascular considerations for patients, health care workers, and health systems during the coronavirus disease 2019 (COVID-19) pandemic Direct oralanticoagulant plasma levels striking increase in severe COVID-19 respiratory syndrome patients treated with antiviral agents.
    keywords: anticoagulation; covid-19; patients; treatment
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        item: #7191 of 7819
          id: cord-348202-6we8e60b
      author: Drake, Daniel H.
       title: Echo in Pandemic: Front Line Perspective, Expanding Role of Ultrasound and Ethics of Resource Allocation
        date: 2020-04-10
       words: 4115
      flesch: 35
     summary: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) associated acute cardiomyopathy is common in critical care patients and is associated with a high mortality. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) associated acute cardiomyopathy is common in critical care patients and is associated with a high mortality.
    keywords: care; covid-19; disease; health; lung; pandemic; patients; ultrasound; ventilation
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        item: #7192 of 7819
          id: cord-348212-c2iibuqa
      author: Cavallo, Federica
       title: Novel coronavirus infection and children
        date: 2020-05-11
       words: 2202
      flesch: 47
     summary: A novel coronavirus from patients with pneumonia in China COVID-19): Situation Report; World Health Organization The role of children in the transmission of mild SARS-CoV-2 infection Acta Paediatr Coronavirus Disease (COVID-19) and the Gastrointestinal System in Children Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: a systematic review and meta-analysis A pneumonia outbreak associated with a new coronavirus of probable bat origin Epidemiology, Pathogenesis, and Control of COVID-19 Detection of Covid-19 in Children in Early SARS-CoV-2 infection in children: Transmission dynamics and clinical characteristics COVID-19): cases in United States Screening and Severity of Coronavirus Disease 2019 (COVID-19) in Children in Epidemiology of COV-ID-19 Echocardiography Recommendations for the diagnosis, prevention and control of the 2019 novel coronavirus infection in children Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts' consensus statement Potential interventions for novel coronavirus in China: A systematic review The Epidemiological Characteristics of an Outbreak of Coronavirus Disease 2019 (COV-ID-19) in Italy COVID-19): cases in United States SARS-CoV-2 Infection in Children Each author declares that he or she has no commercial associations (e.g. consultancies, stock ownership, equity interest, patent/licensing arrangement etc.) that might pose a conflict of interest in connection with the submitted article
    keywords: cases; children; coronavirus; covid-19; disease; symptoms
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        item: #7193 of 7819
          id: cord-348221-w37lfv7e
      author: Zhou, Yongjie
       title: The prevalence of psychiatric symptoms of pregnant and non-pregnant women during the COVID-19 epidemic
        date: 2020-09-19
       words: 3490
      flesch: 45
     summary: The purposes of this study were to assess the prevalence of psychiatric symptoms among pregnant women, and to compare them with non-pregnant women. Our results indicate that during the COVID-19 epidemic in China, pregnant women have an advantage of facing mental problems caused by COVID-19, showing fewer depression, anxiety, insomnia, and PTSD symptoms than non-pregnant women.
    keywords: anxiety; covid-19; epidemic; health; study; symptoms; women
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        item: #7194 of 7819
          id: cord-348222-pd0zzcue
      author: Ansari Ramandi, Mohammad Mostafa
       title: Does the novel coronavirus 2019 like heart more than the other family members of coronaviruses?
        date: 2020-05-11
       words: 1043
      flesch: 35
     summary: In conclusion more molecular and pathological studies are needed for the characterization of acute myocardial injury in COVID-19 patients and shed light on the exact reason for this issue. For instance, we have presented 1 chest computerized tomography (CT) images showing COVID-19 involvement in a PCR positive patient.
    keywords: coronavirus; covid-19; sars
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        item: #7195 of 7819
          id: cord-348246-prwg2wvm
      author: Gabriel, Andrade
       title: The role of psychiatrists in addressing COVID-19 conspiracy theories
        date: 2020-09-01
       words: 1202
      flesch: 40
     summary: Yet, that has not stopped conspiracy theories from emerging. Psychiatrists have a significant role to play in addressing the spread of conspiracy theories regarding COVID-19.
    keywords: conspiracy; covid-19; theories
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        item: #7196 of 7819
          id: cord-348249-zhfrgaxf
      author: Osborne, V.
       title: Systematic benefit-risk assessment for the use of chloroquine or hydroxychloroquine as a treatment for COVID-19: Establishing a framework for rapid decision-making
        date: 2020-05-12
       words: 3923
      flesch: 45
     summary: Several potential key benefits were identified with use of hydroxychloroquine or chloroquine in COVID-19 treatment: reduction in risk of death, reduction in ICU admission, reduction in non-invasive ventilation, reduction in secondary clinical outcomes, reduction in use of oxygen and improved viral load parameters (e.g. virological clearance). A value tree was constructed and key benefits and risks were ranked by two clinicians in order of considered importance.
    keywords: benefit; covid-19; data; hydroxychloroquine; preprint; risk; treatment
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        item: #7197 of 7819
          id: cord-348269-6z0kiapa
      author: Nguyen, Quynh C.
       title: Using 164 Million Google Street View Images to Derive Built Environment Predictors of COVID-19 Cases
        date: 2020-09-01
       words: 5840
      flesch: 44
     summary: Although we have observed strong associations between neighborhood built environment indicators and coronavirus prevalence, we cannot conclude that these characteristics cause higher COVID-19 rates. Firstly, neighborhood built environments that allow greater flow of people into an area or impede social distancing practices may increase residents' risk for contracting the virus.
    keywords: cases; computer; covid-19; data; disorder; environment; health; images; indicators; neighborhood; street; study; zip
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        item: #7198 of 7819
          id: cord-348297-k9fuegol
      author: Zhou, Feng
       title: Shelter Hospital: Glimmers of Hope in Treating Coronavirus 2019
        date: 2020-04-16
       words: 1033
      flesch: 48
     summary: Patients crowded in the fever clinic were transferred to shelter hospitals, which realized the source control of infection and cut off the means of transmission. The workload of medical staff was reduced, and more hospital beds were available for severe and critically ill patients who needed to be hospitalized.
    keywords: covid-19; patients; shelter
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        item: #7199 of 7819
          id: cord-348298-rtm8dn43
      author: O’Connor, Karen
       title: Mental health impacts of COVID-19 in Ireland and the need for a secondary care mental health service response
        date: 2020-05-27
       words: 3799
      flesch: 42
     summary: These features include the morbidity and mortality associated with COVID-19, the relentless media coverage, the social distancing measures, the altered pathways to access care, the changes to the care that is available, the suspension of development plans in mental health services and the economic impact on all populations in society. Funding of mental health services in Ireland has remained consistently low,~6% of the overall health budget (compared to 12% in New Zealand and United Kingdom) (College of Psychiatrists of Ireland, 2020).
    keywords: care; covid-19; health; impact; need; pandemic; people; risk; services
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        item: #7200 of 7819
          id: cord-348327-rgikd4g8
      author: Ueyama, Hiroki
       title: Gender Difference Is Associated With Severity of Coronavirus Disease 2019 Infection: An Insight From a Meta-Analysis
        date: 2020-06-19
       words: 2450
      flesch: 39
     summary: Recognition of the clinical risk factors of severe COVID-19 infection is a high priority to effectively manage this emerging threat of the new virus. The endpoints were the rate of severe COVID-19 infection and death.
    keywords: analysis; coronavirus; covid-19; gender; infection; studies
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        item: #7201 of 7819
          id: cord-348350-pac9ha4q
      author: Martin-Blondel, G
       title: Hydroxychloroquine in COVID-19 patients: what still needs to be known about the kinetics
        date: 2020-05-11
       words: 1827
      flesch: 48
     summary: Moreover, monitoring hydroxychloroquine concentrations in bronchoalveolar fluids of COVID-19 patients could provide additional information on the degree of hydroxychloroquine lung impregnation [9, 10] for a short period of treatment (i.e. few days). The concentrations measured in COVID-19 patients show that hydroxychloroquine exposure tends to be low and in most instances lower than the values reported in SLE patients, in particular for the standard regimen of 200 mg x 3/day.
    keywords: day; hydroxychloroquine; patients
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        item: #7202 of 7819
          id: cord-348351-naktgl9o
      author: Rajkumar, Ravi Philip
       title: Suicides related to the COVID-19 outbreak in India: a pilot study of media reports
        date: 2020-06-05
       words: 1159
      flesch: 47
     summary: This is underlined by the fact that one-fourth of deaths in this series occurred in hospital settings high number of reported suicides that occurred in hospitalized patients (over ¼ of the cases in this series). As direct interaction with the families of suicide victims is difficult during a disease outbreak, information regarding such deaths must be obtained through indirect means.
    keywords: covid-19; deaths; outbreak; suicide
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        item: #7203 of 7819
          id: cord-348358-dg3sa9ho
      author: Yüce, Meltem Özden
       title: An analysis of YouTube videos as educational resources for dental practitioners to prevent the spread of COVID-19
        date: 2020-07-23
       words: 3352
      flesch: 49
     summary: The use of YouTube may Mann-Whitney U test with Bonferroni correction: † p < 0.008 significantly higher than ADA; ‡ p < 0.008 significantly higher than dental health professional; § p < 0.008 significantly higher than dental health centres; ‖ p < 0.008 significantly higher than news have a positive impact on professional and public education; during the outbreaks in the past such as Ebola outbreak in 2014 and Zika virus epidemic in 2016 and H1N1 Influenza pandemic in 2009, YouTube videos have been reported to be watched millions of times [14] . Also, all videos were classified according to the source of upload, categorised as American Dental Association (ADA), dental health professionals (general dentists, specialists), dental health centres, news and information websites.
    keywords: covid-19; dental; health; information; videos; youtube
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        item: #7204 of 7819
          id: cord-348364-jb0lvhq5
      author: Rehman, Tyler
       title: Spontaneous Pneumothorax in an Elderly Patient With Coronavirus Disease (COVID-19) Pneumonia
        date: 2020
       words: 1328
      flesch: 41
     summary: As of June 2020, few cases of nonintubated patients developing pneumothorax had been documented. Spontaneous pneumothorax is usually attributed to a bleb rupture.
    keywords: covid-19; patient; pneumonia; pneumothorax
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        item: #7205 of 7819
          id: cord-348365-e90544er
      author: Alharthy, Abdulrahman
       title: Lung Injury in COVID-19—An Emerging Hypothesis
        date: 2020-07-24
       words: 1405
      flesch: 33
     summary: A minority of COVID-19 patients have fulminant disease, which is characterized by acute respiratory distress syndrome (ARDS), multisystem organ failure (MSOF), neurological manifestations, thromboembolic phenomena, and CRS. 8, 9 However, neurogenic pulmonary edema could indeed occur in patients with severe COVID-19 pneumonia although it should not be characterized as a form of ARDS, but rather as a noncardiogenic interstitial lung edema with peripheral lung zone distribution, which could be observed in viral pneumonitis and after brain injury.
    keywords: covid-19; injury; lung; patients; syndrome
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        item: #7206 of 7819
          id: cord-348388-nkosag8m
      author: Nirenberg, Michael S.
       title: Foot manifestations in a patient with COVID-19 and Epstein-Barr virus: A case study
        date: 2020-06-22
       words: 1678
      flesch: 55
     summary: Also, since numerous diseases are known to cause cutaneous manifestations, including some that can affect the feet [21, 22] , it is not known if skin issues observed in COVID-19 patients are due to COVID-19 or the result of a co-infection, perhaps unrecognized. Available at SSRN 3555268 Child with liver transplant recovers from COVID-19 infection.
    keywords: case; covid-19; foot; manifestations; patient
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        item: #7207 of 7819
          id: cord-348406-tg0c51oi
      author: Atrah, Hasan I
       title: Alternative management of Covid-19 infection
        date: 2020-07-08
       words: 2361
      flesch: 32
     summary: The differences between the current management of Covid-19 infection and the alternative management is that we are aiming actively in the latter at reduction of the development of cytokine storm complication of Covid-19 infections, reduction of the need for ICU admission, and most importantly, reduction of the mortality rate. key: cord-348406-tg0c51oi authors: Atrah, Hasan I title: Alternative management of Covid-19 infection date: 2020-07-08 journal: Scott Med J DOI: 10.1177/0036933020941497 sha: doc_id: 348406 cord_uid: tg0c51oi Cytokine storm is a life-threatening complication of Covid-19 infection.
    keywords: covid-19; cytokine; immune; infection; storm; treatment
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        item: #7208 of 7819
          id: cord-348414-y6vh63xk
      author: Berger, W. R.
       title: Dutch cardiology residents and the COVID-19 pandemic: Every little thing counts in a crisis
        date: 2020-11-03
       words: 1516
      flesch: 43
     summary: The COVID-19 pandemic has overwhelmed healthcare systems worldwide, and a large part of regular cardiology care came to a quick halt. A Dutch nationwide survey showed that 41% of cardiology residents suspended their training and worked at COVID-19 cohort units for up to 3 months.
    keywords: care; covid-19; pandemic; residents
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        item: #7209 of 7819
          id: cord-348422-werg9ofa
      author: Shamsah, Mohammed A
       title: Right atrial thrombus in a patient with COVID-19 pneumonia: a case report
        date: 2020-09-04
       words: 1888
      flesch: 37
     summary: Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy The stimulation of thrombosis by hypoxia COVID-19-driven endothelial damage: complement, HIF-1, and ABL2 are potential pathways of damage and targets for cure Coagulopathy and antiphospholipid antibodies in patients with Covid-19 Viral infections and antiphospholipid antibodies Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy ISTH interim guidance on recognition and management of coagulopathy in COVID-19 Hypercoagulability of COVID-19 patients in intensive care unit. Expert consensus has recommended prophylactic anticoagulation in COVID-19 patients due to the risk of thrombo-embolism.
    keywords: covid-19; embolism; patients; pneumonia; pulmonary; treatment
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        item: #7210 of 7819
          id: cord-348430-8xk4dt7t
      author: Bragazzi, Nicola Luigi
       title: COVID‐19 knowledge prevents biologics discontinuation: Data from an Italian multicenter survey during RED‐ZONE declaration
        date: 2020-05-28
       words: 1954
      flesch: 26
     summary: key: cord-348430-8xk4dt7t authors: Bragazzi, Nicola Luigi; Riccò, Matteo; Pacifico, Alessia; Malagoli, Piergiorgio; Kridin, Khalaf; Pigatto, Paolo; Damiani, Giovanni title: COVID‐19 knowledge prevents biologics discontinuation: Data from an Italian multicenter survey during RED‐ZONE declaration date: 2020-05-28 journal: Dermatol Ther DOI: 10.1111/dth.13508 sha: doc_id: 348430 cord_uid: 8xk4dt7t SARS‐CoV‐2 become pandemics and there is still a dearth of data about its the potentially among dermatological patients under biologics. To the best of our knowledge, there is a dearth of data concerning the COVID-19 perceptions of dermatological patients under biologics, a therapy traditionally associated to an increased risk of infections.
    keywords: biologics; covid-19; disease; knowledge; patients; psoriasis
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        item: #7211 of 7819
          id: cord-348435-z1c16thl
      author: Jiricka-Pürrer, Alexandra
       title: City tourism pre- and post-covid-19 pandemic – Messages to take home for climate change adaptation and mitigation?
        date: 2020-09-30
       words: 6212
      flesch: 44
     summary: The paper presents the status quo on climate change impacts on city tourism in Austria describing the impacts by air travel and a short stay on the greenhouse gas emissions and the changing conditions in the city. The analysis of challenges shows a strong overlap of adaptation targets in city tourism with adaptation challenges for city planning including connection to the sub-urban surrounding areas to confront climate change impacts.
    keywords: areas; austria; change; city; climate; covid-19; heat; pandemic; source; summer; tourism; travel; vienna
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        item: #7212 of 7819
          id: cord-348436-mwitcseq
      author: Bu, F.
       title: Time-use and mental health during the COVID-19 pandemic: a panel analysis of 55,204 adults followed across 11 weeks of lockdown in the UK
        date: 2020-08-21
       words: 4857
      flesch: 41
     summary: This relationship between time use and mental health is bidirectional, as mental ill health has been shown to predict lower physical activity 22 , lower motivation to engage in leisure activities 23 and increased engagement in screen time 24 . key: cord-348436-mwitcseq authors: Bu, F.; Steptoe, A.; Mak, H. W.; Fancourt, D. title: Time-use and mental health during the COVID-19 pandemic: a panel analysis of 55,204 adults followed across 11 weeks of lockdown in the UK date: 2020-08-21 journal: nan DOI: 10.1101/2020.08.18.20177345 sha: doc_id: 348436 cord_uid: mwitcseq There is currently major concern about the impact of the global COVID 19 outbreak on mental health.
    keywords: activities; covid-19; health; license; preprint; study; time; use
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        item: #7213 of 7819
          id: cord-348458-dwj90mbq
      author: Narula, Nupoor
       title: Cardiology Practice and Training Post-COVID-19: Achieving “Normalcy” After Disruption
        date: 2020-06-22
       words: 1871
      flesch: 45
     summary: While none of us have 163 absolute foresight, we must learn from the harsh lessons faced and plan for 164 medical changes, including the deluge of cardiac care patients that will fill our 165 clinics, flexibility of FIT education to support cardiovascular training, and 166 continued integration of clinical science and technology. The bipartisan CARES legislation has 79 allocated at least 50 billion dollars to support hospital systems and health care 80 providers 11 , and private physician offices and faculty practices are eligible to 81 apply for several loan-based programs, including the Paycheck Protection 82 Program and Emergency Economic Injury Disaster Loans.
    keywords: care; covid-19; disease; health; pandemic; patients
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        item: #7214 of 7819
          id: cord-348459-v3e1zqpa
      author: Sung, J.
       title: Development and Validation of a Simple Risk Score for Diagnosing COVID-19 in the Emergency Room
        date: 2020-08-14
       words: 2558
      flesch: 45
     summary: Chest X ray results are likely to have clinical utility in risk-stratification of COVID-19 patients, but our study was not sufficiently powered to detect this difference. In summary, we developed a simple, easy-to-implement bedside scoring system for COVID-19 risk stratification among patients who are being admitted to the hospital.
    keywords: covid-19; license; medrxiv; patients; preprint
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        item: #7215 of 7819
          id: cord-348464-1c08mb2k
      author: Winter, Taylor
       title: Evaluation of the English Version of the Fear of COVID-19 Scale and Its Relationship with Behavior Change and Political Beliefs
        date: 2020-06-15
       words: 3463
      flesch: 47
     summary: The fear of COVID-19 scale: development and initial validation Psychometric evaluation of the Arabic version of the fear of COVID-19 scale Coughing while asian': living in fear as racism feeds off coronavirus panic. stuff.co.nz Fear of COVID-19 scale: psychometric characteristics, reliability and validity in the israeli population New Zealand should consider quitting lockdown early, David Seymour says Why are conservatives less concerned about the coronavirus (COVID-19) than liberals?
    keywords: covid-19; fcv-19s; fear; participants; sample; scale
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        item: #7216 of 7819
          id: cord-348494-yx11ucrb
      author: Ali, Kamran
       title: Coronavirus disease 2019 (COVID-19): challenges and management of aerosol-generating procedures in dentistry
        date: 2020-06-26
       words: 1653
      flesch: 35
     summary: Kamran Ali 1 and Mahwish Raja 2 • For now practitioners should focus on emergency and preventive dental care as evidence-based clinical protocols are needed prior to commencing invasive dental procedures • Dental surgeries represent a potentially high-risk clinical environment and dental professionals must follow the most updated national and international guidelines in letter and spirit to protect themselves as well as their staff, patients, and the general public from further spread of COVID-19 • Additional costs related to PPE, staff training, and the investment to improve clinical environment coupled with low rates of patient turn-over will have a knock-on effect on the financial resources of dental businesses. Therefore, governments and healthcare bodies must be urged to come up with concrete strategies to support the dental profession and keep dental practices financially viable • Finally, dental professionals should not remain at the receiving end of cross infection control guidelines and should explore appropriate platforms to actively participate in research aimed at informing evidence-based protocols to limit the spread of COVID-19 in dental environments.
    keywords: cases; contamination; patients; surgery
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        item: #7217 of 7819
          id: cord-348501-8cvtqj7w
      author: Beyzaee, Amir Mohammad
       title: Rituximab as the treatment of pemphigus vulgaris in the COVID‐19 pandemic era: A narrative review
        date: 2020-10-20
       words: 2513
      flesch: 33
     summary: Although evidence for treating PV patients with rituximab in COVID-19 pandemic is limited, and outcomes of MS patients taking rituximab was controversial, until sufficient evidence as a guideline for pemphigus and COVID-19 treatment is available, we advocate caution commencing rituximab for pemphigus patients and adherence to basic principles of infection control and decreasing drug induced immunosuppression as possible. 28 High amount of IL-6, a strong factor related to mortality in COVID-19 patients, is seen in patients given rituximab and secukinumab, that can be due to the failure of rituximab and secukinumab to modulate IL-6.
    keywords: covid-19; patients; pemphigus; rituximab; treatment
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        item: #7218 of 7819
          id: cord-348521-ai7d634u
      author: Atif, Muhammad
       title: COVID-19 and community pharmacy services in Pakistan: challenges, barriers and solution for progress
        date: 2020-06-15
       words: 2338
      flesch: 38
     summary: The importance of community pharmacy services during COVID-19 havoc could be gauged by the fact that many developed nations have amended pharmaceutical policies, introduced reimbursement schemes and released new instructions for community pharmacies to expand pharmacy services key: cord-348521-ai7d634u authors: Atif, Muhammad; Malik, Iram title: COVID-19 and community pharmacy services in Pakistan: challenges, barriers and solution for progress date: 2020-06-15 journal: J Pharm Policy Pract DOI: 10.1186/s40545-020-00240-4 sha: doc_id: 348521 cord_uid: ai7d634u In the wake of atrocious rise in COVID-19 cases, developed countries are leveraging a range of community pharmacy services with the goal of improving access to essential medication and healthcare services.
    keywords: community; covid-19; pakistan; pharmacists; pharmacy; services
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        item: #7219 of 7819
          id: cord-348535-tvs1snq8
      author: Ottaviani, Silvia
       title: What is the best drug to treat COVID-19? The need for randomized controlled trials
        date: 2020-05-19
       words: 1412
      flesch: 39
     summary: For example, we have observed 11 that use of baricitinib for 10 days is associated with viral rebound in nasopharyngeal swabs in rapidly recovered and discharged patients, and thus have recommended longer use in the large randomised studies in which it is included, and we suggest again that comparisons between different therapies or placebo are likely to yield more informative results than randomised studies comparing 10 days of intravenous remdesevir with 5 days (https://benevolent.ai/news/potential-treatment-for-covid-19-identified-by-benevolentai-usingartificial-intelligence-enters-clinical-testing And https://investor.lilly.com/news-releases/news-release-details/lilly-begins-clinical-testingtherapies-covid-19). Baseline criteria between the 3 groups were well-matched (a criticism of one of the hydroxychloroquine randomised studies is this was not the case 13 ) and follow up was appropriate.
    keywords: covid-19; patients; studies; study
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        item: #7220 of 7819
          id: cord-348537-rsdyiygo
      author: Pignatti, Marco
       title: How the COVID-19 pandemic changed the Plastic Surgery activity in a regional referral center in Northen Italy
        date: 2020-05-15
       words: 2274
      flesch: 42
     summary: Patients already booked in outpatients clinic; patients needing follow up for previous surgeries (either complicated or complex to manage at home); patients looking for a surgeon The Plastic Surgery outpatient clinic activity during the overall COVID-19 period (7 weeks 2020) and during the corresponding period of 2019 are shown STOP of elective surgery FIGURE 6. However the use of internet tools for monitoring reconstructive surgery patients has been largely described 22, 23, 24 .Instant sharing of images or video calls allow plastic surgeons to make an easy consultation, filtering only clinical cases that really need to be evaluated in person for an adequate treatment.
    keywords: covid-19; patients; period; plastic; surgery; weeks
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        item: #7221 of 7819
          id: cord-348566-48hovz3f
      author: Nichols, James H
       title: A Laboratory Risk Assessment during the Coronavirus (COVID-19) Pandemic
        date: 2020-04-16
       words: 1251
      flesch: 40
     summary: Social distancing may be challenging in those situations, and additional risk measures of limiting staff to a single operator in small satellite laboratories, keeping staff at home if they do not feel well, and limiting face-to-face meetings can further help reduce transmission among laboratory staff. Point-of-care testing (POCT) devices are a particular risk category to consider with the COVID-19 pandemic. Simple common sense, communication and reinforcement of Standard Precautions can reduce risk to laboratory staff during this COVID-19 pandemic.
    keywords: covid-19; laboratory; risk; staff
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        item: #7222 of 7819
          id: cord-348567-rvwxysvc
      author: Panfili, F. M.
       title: Possible role of vitamin D in Covid-19 infection in pediatric population
        date: 2020-06-15
       words: 5402
      flesch: 30
     summary: Vitamin D supplementation, as already described, seems to decrease proinflammatory cytokines in the lung via modulation of both macrophages and T lymphocytes activity [24] . At the moment of writing, an interventional randomized clinical trial has been proposed at the University of Granada, with enrollment of 200 participants, proposing vitamin D supplementations (a single dose of 25,000 UI of vitamin D) in preventing and treating mild forms of suspected Covid-19 [68] .
    keywords: cells; covid-19; disease; levels; patients; pneumonia; role; study; supplementation; vitamin; vitamin d
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        item: #7223 of 7819
          id: cord-348573-uyuazdhk
      author: Soraci, Paolo
       title: Validation and Psychometric Evaluation of the Italian Version of the Fear of COVID-19 Scale
        date: 2020-05-04
       words: 3935
      flesch: 43
     summary: Future studies should also evaluate if individuals with underlying medical conditions associated with a higher risk of death from COVID-19 (e.g., diabetes, hypertension, coronary heart disease, pre-existing respiratory conditions) may experience increased levels of COVID-19 fear. Further investigation on bigger and more representative samples of Italian participants is needed to confirm the preliminary results provided by the present study (e.g., a nationally representative sample with more male participants).
    keywords: anxiety; covid-19; depression; fcv-19s; fear; italian; items; scale
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        item: #7224 of 7819
          id: cord-348588-s85sseqo
      author: Gharakhanlou, Navid Mahdizadeh
       title: Spatio-temporal simulation of the novel coronavirus (COVID-19) outbreak using the agent-based modeling approach (Case study: Urmia, Iran)
        date: 2020-07-30
       words: 5540
      flesch: 48
     summary: Precede the outbreak of COVID-19 from Qom to all cities in Iran, the Iranian government in 350 order to reduce the rate of COVID-19 outbreak closed all schools and educational centers on February 351 21. In this research, the outbreak of COVID-19 disease was simulated with the help of ABM so that all agents considered in the ABM along with their attributes and behaviors as well as the environment of the ABM were described.
    keywords: abm; agents; covid-19; human; model; number; outbreak; people
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        item: #7225 of 7819
          id: cord-348614-im7qtr9k
      author: Yánez Benítez, Carlos
       title: International cooperation group of emergency surgery during the COVID-19 pandemic
        date: 2020-10-13
       words: 3981
      flesch: 36
     summary: When asked for the number of emergency cases evaluated in the emergency department, the vast majority (82%) perceived a lower frequency of emergency surgical emergencies during the studied period. When asked about the transport of emergency surgical cases to the OR, almost two-thirds (64%) answered that COVID-19 emergency surgical cases were escorted directly to the OR, not stopping in the Preoperative-Postoperative Anesthesia Care Unit (Po/PACU).
    keywords: covid-19; emergency; equipment; management; pandemic; ppe; recommendations; respondents; surgery; use
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        item: #7226 of 7819
          id: cord-348619-rnjvdu12
      author: Lai, Lucinda
       title: Digital triage: Novel strategies for population health management in response to the COVID-19 pandemic()
        date: 2020-10-26
       words: 3393
      flesch: 39
     summary: They worked with Providence and Microsoft to build a similar COVID-19 screener tool to modify and deploy J o u r n a l P r e -p r o o f for MGB patients and the broader regional community of patients seeking triage guidance. This triage system would have to handle inquiries from existing MGB patients, MGB employees, J o u r n a l P r e -p r o o f and the general public and route through existing (ambulatory clinics, virtual urgent care (MGB on Demand)) and new (telephone hotline and chatbot) care settings.
    keywords: care; chatbot; covid-19; healthcare; hospital; mgb; patients; system; triage
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        item: #7227 of 7819
          id: cord-348652-7n7rnonw
      author: Ramos, Roberta Pulcheri
       title: Thrombosis and anticoagulation in COVID-19
        date: 2020
       words: 1025
      flesch: 29
     summary: In fact, vascular lesions have been identified in patients with ARDS, not only in autopsy studies but also in ICU patients by means of pulmonary angiography. ARDS or not Pathological evidence of pulmonary thrombotic phenomena in severe COVID-19 Prediction models for diagnosis and prognosis of covid-19 infection: systematic review and critical appraisal High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Prevention, Diagnosis, and Treatment of VTE in Patients With COVID-19: CHEST Guideline and Expert Panel Report Evaluation of variation in D-dimer levels among COVID-19 and bacterial pneumonia: a retrospective analysis Intermediate Dose Low-Molecular-Weight Heparin for Thrombosis Prophylaxis: Systematic Review with Meta-Analysis and Trial Sequential Analysis Findings in Severe COVID-19: A Retrospective Observational Study
    keywords: covid-19; levels; patients
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        item: #7228 of 7819
          id: cord-348658-fz5nfdf9
      author: Weiner, Joseph A.
       title: Learning from the past: did experience with previous epidemics help mitigate the impact of COVID-19 among spine surgeons worldwide?
        date: 2020-06-04
       words: 5272
      flesch: 46
     summary: Respondents with and without prior epidemic experience (e.g., SARS, H1NI, MERS) were assessed on preparedness and response via univariate and multivariate modeling. There was no difference in access to testing between surgeons with prior epidemic experience and those without epidemic experience (84.5% vs 82.2%, p = 0.440)
    keywords: covid-19; epidemic; experience; health; impact; pandemic; preparedness; respondents; spine; surgeons
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        item: #7229 of 7819
          id: cord-348674-ifcfyecf
      author: Goh, Khean‐Lee
       title: COVID‐19 and the digestive system: More than just a “flu”
        date: 2020-06-05
       words: 964
      flesch: 46
     summary: It is interesting to speculate, with the occurrence of a cytokine storm in COVID-19 infections, whether biological agents that are used for severe cases of IBD may in fact help with the treatment of severe COVID-19 infection. In this June issue, JGH Open has published two Leading Articles on the COVID-19 infection: the first is the Asian Pacific Association of Gastroenterology (APAGE) Inflammatory Bowel Disease (IBD) Working Party Guidelines on the IBD during the COVID-19 pandemic 1 and the second an excellent review article by Aguila et al. focusing on gastrointestinal and liver complications of COVID-19 infection and endoscopy practice.
    keywords: covid-19; ibd; patients
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        item: #7230 of 7819
          id: cord-348696-86nbwon2
      author: Güemes-Villahoz, Noemi
       title: Novel Insights into the Transmission of SARS-CoV-2 Through the Ocular Surface and its Detection in Tears and Conjunctival Secretions: A Review
        date: 2020-08-18
       words: 4203
      flesch: 37
     summary: Gene Rep Detection of SARS-CoV-2 in different types of clinical specimens Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS-CoV-2 infection The evidence of SARS-CoV-2 infection on ocular surface Risk factors for SARS transmission from patients requiring intubation: a multicentre investigation in Toronto -nCoV transmission through the ocular surface must not be ignored Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease Characteristics of ocular findings of patients with coronavirus disease (COVID-19 SARS-CoV-2 RNA detection in tears and conjunctival secretions of COVID-19 patients with conjunctivitis Ocular screening in severe acute respiratory syndrome Blood-retinal barrier breakdown in experimental coronavirus retinopathy: association with viral antigen, inflammation, and VEGF in sensitive and resistant strains The role of apoptosis within the retina of coronavirus-infected mice COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Expression of the SARS-CoV-2 cell receptor gene ACE2 in a wide variety of human tissues Expression analysis of 2019-nCoV related ACE2 and TMPRSS2 in eye tissues Angiotensin II and its receptor subtypes in the human retina Mechanism of the action between the SARS-CoV S240 protein and the ACE2 receptor in eyes Immune defense at the ocular surface Inhibition of SARS pseudovirus cell entry by lactoferrin binding to heparan sulfate proteoglycans Viral antibodies in normal tears The ocular surface and the coronavirus disease 2019: does a dual 'ocular route' exist? Evaluation of ocular symptoms and tropism of SARS-CoV-2 Ophthalmologic evidence against the interpersonal transmission of 2019 novel coronavirus through conjunctiva. The new coronavirus SARS-CoV-2 belongs to the same betacoronavirus family as the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndromerelated coronavirus (MERS-CoV), which were responsible for the outbreaks of severe acute respiratory syndrome (SARS) in 2002 and 2012, respectively [1, 2] .
    keywords: conjunctival; conjunctivitis; cov-2; covid-19; eye; patients; sars; tears; transmission; virus
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        item: #7231 of 7819
          id: cord-348709-y1tws6p9
      author: Yusoff, Muhamad Saiful Bahri
       title: Sustainable Medical Teaching and Learning During the COVID-19 Pandemic: Surviving the New Normal
        date: 2020-06-30
       words: 1709
      flesch: 30
     summary: It should be noted that if the duration for the MCO following the COVID-19 outbreak were to exceed two months, which is now the case, it was essential for medical schools to activate emergency risk management for the implementation of online teaching and learning during the outbreak. Online teaching and learning have rapidly become a delivery method for higher education in many countries including Malaysia.
    keywords: covid-19; face; learning; online; teaching
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        item: #7232 of 7819
          id: cord-348717-qgny6f6y
      author: Shumba, Constance
       title: Reorienting Nurturing Care for Early Childhood Development during the COVID-19 Pandemic in Kenya: A Review
        date: 2020-09-25
       words: 8591
      flesch: 41
     summary: The reluctance of parents to visit clinics due to fear of infection with COVID-19 may also interrupt immunization and other child health programs [56] . Early Chilhood Matters Cash transfer programs have differential effects on health: A review of the literature from low and middle-income countries The Cash Dividend: The Rise of Cash Transfer Programs in Sub-Saharan Africa An emergency cash transfer program promotes weight gain and reduces acute malnutrition risk among children 6-24 months old during a food crisis in Niger Romania's Abandoned Children Care for Child Development: An intervention in support of responsive caregiving and early child development.
    keywords: access; care; caregivers; children; covid-19; development; families; health; impacts; kenya; learning; need; pandemic; services; support
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        item: #7233 of 7819
          id: cord-348725-vksombro
      author: Teo, Leng Woon
       title: "Coping with COVID-19: perspectives of student radiographers"
        date: 2020-05-29
       words: 2036
      flesch: 48
     summary: Looking forward, we hope to see better synergy between traditional lectures and e-learning in the curriculum, allowing for maximised efficiency in terms of content delivery, practical experience and student learning. The aforementioned changes impacted radiography students to a large extent.
    keywords: covid-19; learning; measures; radiography; singapore; students
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        item: #7234 of 7819
          id: cord-348748-rxyh58eu
      author: Gorospe, Luis
       title: COVID-19: Thoracic Diagnostic Interventional Procedures in Troubled Times()
        date: 2020-09-07
       words: 1278
      flesch: 38
     summary: Coronavirus disease (COVID-19): a scoping review COVID-19: impact on cancer workforce and delivery of care Cancer treatment adaptations in the COVID-19 era Meeting the challenge of the 2019 novel coronavirus disease in patients with cancer What the oncologist needs to know about COVID-19 infection in cancer patients Managing cancer care during the COVID-19 pandemic: agility and collaboration toward a common goal The impact of the COVID-19 pandemic on cancer patients Managing patients with cancer in the COVID-19 era Managing COVID-19 in patients with cancer: a double blow for oncologists Cancer in the time of COVID: expert opinion on how to adapt current practice Provision of cancer care during the COVID-19 pandemic Challenges in lung cancer therapy during the COVID-19 pandemic Nosocomial transmission of emerging viruses via aerosol-generating medical procedures SARS-CoV-2 transmission in patients with cancer at a tertiary care hospital in Wuhan, China Managing COVID-19 in the oncology clinic and avoiding the distraction effect Radiology department preparedness for COVID-19: radiology scientific expert panel Some publications have addressed the clinical management of cancer patients in the current SARS-CoV-2 pandemic, but there are no specific guidelines for performing thoracic diagnostic interventional procedures in patients with tumors who are also infected with SARS-CoV-2.
    keywords: cancer; covid-19; patients; sars
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        item: #7235 of 7819
          id: cord-348755-2g5gi1du
      author: Chow, D. S.
       title: Development and External Validation of a Prognostic Tool for COVID-19 Critical Disease
        date: 2020-05-11
       words: 2862
      flesch: 37
     summary: The purpose of this study is to develop and externally validate a prognostic model/clinical tool for predicting COVID-19 critical disease at presentation to medical care. Methods: This is a retrospective study of a prognostic model for the prediction of COVID-19 critical disease where critical disease was defined as ICU admission, ventilation, and/or death.
    keywords: covid-19; critical; disease; model; patients; preprint
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        item: #7236 of 7819
          id: cord-348771-gr7oa9up
      author: Karri, Jay
       title: Point of care procedures in physiatry: Practice considerations during the Covid-19 pandemic
        date: 2020-05-08
       words: 1695
      flesch: 21
     summary: While the CDC and CMS recommend for elective procedures to be rescheduled in order to preserve healthcare resources and personnel, these recommendations do not account for the spectrum of physiatry procedures and the uniquely vulnerable population we serve. While elective physiatry procedures may not carry life-sustaining benefits, they can provide meaningful improvements in pain ( 16 .
    keywords: covid-19; physiatry; procedures; recommendations; risk
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        item: #7237 of 7819
          id: cord-348773-ulnc9gdv
      author: Hammoud, H.
       title: Post mortem pathological findings in COVID-19 cases: A Systematic Review
        date: 2020-10-14
       words: 5077
      flesch: 45
     summary: SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19 CC-BY 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity Complete postmortem data in a fatal case of COVID-19: clinical, radiological and pathological correlations Neuropathologic features of four autopsied COVID-19 patients Histopathological findings in the advanced natural evolution of the SARS-CoV-2 infection Fatal pulmonary fibrosis: a post-COVID-19 autopsy case Postmortem Kidney Pathology Findings in Patients with COVID-19 No Autopsies on COVID-19 Deaths: A Missed Opportunity and the Lockdown of Science The role of forensic pathologists in coronavirus disease 2019 infection: The importance of an interdisciplinary research Management of the corpse with suspect, probable or confirmed COVID-19 respiratory from corpses, including body fluids, in morgue structures and during autopsy practice Review: The safe handling of a corpse (suspected) with COVID-19 Middle East Respiratory Syndrome Coronavirus Infection in the United Arab Emirates Lung pathology of fatal severe acute respiratory syndrome Autopsy Findings in Eight Patients With Fatal H1N1 Influenza Interesting postmortem findings in a H1N1 influenza-positive pneumonia patient Histopathological and immunohistochemical findings of 20 autopsy cases with 2009 H1N1 virus infection Histopathological autoptic findings in 8 patients with pandemic influenza A (H1N1) pneumonia Systematic review of COVID-19 related myocarditis: Insights on management and outcome A clinicopathological study of three cases of severe acute respiratory syndrome (SARS) Analysis of deaths during the severe acute respiratory syndrome (SARS) epidemic in Singapore: challenges in determining a SARS diagnosis Multiple organ infection and the pathogenesis of SARS Acute renal failure in SARS patients: more than rhabdomyolysis SARSassociated viral hepatitis caused by a novel coronavirus: Report of three cases Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis Cerebrospinal fluid findings in COVID-19 patients with neurological symptoms Detection of severe acute respiratory syndrome coronavirus in the brain: potential role of the chemokine mig in pathogenesis No ethical approval is required. key: cord-348773-ulnc9gdv authors: Hammoud, H.; Bendari, A.; Bendari, T.; Bougmiza, I. title: Post mortem pathological findings in COVID-19 cases: A Systematic Review date: 2020-10-14 journal: nan DOI: 10.1101/2020.10.11.20210849 sha: doc_id: 348773 cord_uid: ulnc9gdv Abstract Background: The current COVID-19 pandemic is considered one of the most serious public health crisis over the last few decades.
    keywords: articles; cases; covid-19; findings; license; medrxiv; patients; preprint; sars
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        item: #7238 of 7819
          id: cord-348777-pk9y6vfp
      author: Ding, Cheng
       title: Effect of Corticosteroid Therapy on the Duration of SARS-CoV-2 Clearance in Patients with Mild COVID-19: A Retrospective Cohort Study
        date: 2020-09-28
       words: 3620
      flesch: 40
     summary: This study aims to investigate the association between corticosteroid therapy and the duration of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) clearance among patients with mild COVID-19. Corticosteroid therapy in patients with mild COVID-19 was not associated with the duration of SARS-CoV-2 clearance, suggesting that the use of corticosteroids may not be beneficial for patients with mild COVID-19 and should be prudently recommended in clinical practice.
    keywords: clearance; coronavirus; corticosteroid; covid-19; patients; rna; sars; therapy
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        item: #7239 of 7819
          id: cord-348786-25o7tam4
      author: Mella, Alberto
       title: Case series of six kidney transplanted patients with COVID‐19 pneumonia treated with tocilizumab
        date: 2020-06-17
       words: 1510
      flesch: 28
     summary: key: cord-348786-25o7tam4 authors: Mella, Alberto; Mingozzi, Silvia; Gallo, Ester; Lavacca, Antonio; Rossetti, Maura; Clari, Roberta; Randone, Olga; Maffei, Stefano; Salomone, Mario; Imperiale, Daniele; Biancone, Luigi title: Case series of six kidney transplanted patients with COVID‐19 pneumonia treated with tocilizumab date: 2020-06-17 journal: Transpl Infect Dis DOI: 10.1111/tid.13348 sha: doc_id: 348786 cord_uid: 25o7tam4 Few reports described the outcome of kidney transplanted patients (KTs) affected by COVID‐19 treated with interleukin‐6 receptor inhibitor tocilizumab (TCZ). In conclusion, despite these data should be evaluated with extremely caution and have some limitations (selection bias, availability of IL-6 dosage in all patients, absence of CD4+/CD8 + count), our study confirmed that kidney transplanted patients are a high-risk group with significant COVID-19-associated mortality.
    keywords: covid-19; kidney; patients; tcz; transplant
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        item: #7240 of 7819
          id: cord-348787-8htlnb52
      author: Hettiarachchi, Dineshani
       title: Ethical Responses to the COVID-19 Pandemic—Lessons from Sri Lanka
        date: 2020-11-03
       words: 3757
      flesch: 47
     summary: The Buddhist teachings of self-discipline that prevails within Sri Lankan society have likely played a role in the adherence to the strict rules set by the government during the curfew and lockdown periods. key: cord-348787-8htlnb52 authors: Hettiarachchi, Dineshani; Noordeen, Nafeesa; Gamakaranage, Chanpika; Somarathne, E. A. Rumesh Buddhika D.; Jayasinghe, Saroj title: Ethical Responses to the COVID-19 Pandemic—Lessons from Sri Lanka date: 2020-11-03 journal: Asian Bioeth Rev DOI: 10.1007/s41649-020-00153-z sha: doc_id: 348787 cord_uid: 8htlnb52 The COVID-19 pandemic has undoubtedly become an era-defining challenge for the entire world.
    keywords: care; covid-19; ethics; government; health; lanka; lockdown; pandemic; sri
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        item: #7241 of 7819
          id: cord-348803-2lix3a0u
      author: Ikemura, K.
       title: Using Automated-Machine Learning to Predict COVID-19 Patient Survival: Identify Influential Biomarkers
        date: 2020-10-14
       words: 3798
      flesch: 53
     summary: From our literature review, this will be the largest COVID-19 patient cohort to train ML models and the first to utilize autoML. In many such ML studies, researchers are only training on one kind of ML model (XGBoost, Random Forest, etc.)
    keywords: aucpr; automl; covid-19; models; patients; preprint; variables
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        item: #7242 of 7819
          id: cord-348806-yi9vbgwj
      author: Saladino, Valeria
       title: The Psychological and Social Impact of Covid-19: New Perspectives of Well-Being
        date: 2020-10-02
       words: 4012
      flesch: 31
     summary: Online psychological services avoid geographical barriers and are suitable to become a useful integrated tool in addition to traditional psychotherapy (APS, 2020; Perrin et al., 2020). Online psychological services provide several advantages, especially in the current situation of pandemic.
    keywords: anxiety; covid-19; et al; health; impact; mental; online; pandemic; stress
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        item: #7243 of 7819
          id: cord-348807-9xxc5hyl
      author: Cuomo, Raphael E.
       title: Sub-national longitudinal and geospatial analysis of COVID-19 tweets
        date: 2020-10-28
       words: 3241
      flesch: 37
     summary: Z-scores for trends from the resultant emerging hot spot analysis for COVID-19 cases per capita were compared to z-scores for trends from emerging hot spot analysis for COVID-19 tweets per capita. Confirmed COVID-19 cases, deaths, and recoveries were obtained from Johns Hopkins University Github CSSEGISandData/COVID-19 repository [2] .
    keywords: cases; covid-19; data; health; states; time; tweets; united
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        item: #7244 of 7819
          id: cord-348813-v1sdodz9
      author: Kefale, Belayneh
       title: Prevalence and Risk Factors of Thromboembolism among Patients With Coronavirus Disease-19: A Systematic Review and Meta-Analysis
        date: 2020-10-19
       words: 3592
      flesch: 35
     summary: Deep vein thrombosis and pulmonary embolism Epidemiology of venous thromboembolism Incidence of and mortality from venous thromboembolism in a real-world population: the Q-VTE Study Cohort Morbidity, mortality and costs associated with venous thromboembolism in hospitalized patients with cancer Thromboprophylaxis and mortality among patients who developed venous thromboembolism in seven major hospitals in Saudi Arabia Direct medical costs of venous thromboembolism and subsequent hospital readmission rates: an administrative claims analysis from 30 managed care organizations Deep vein thrombosis in Europe-health-related quality of life and mortality Health-related quality of life and mortality in patients with pulmonary embolism: a prospective cohort study in seven European countries Economic burden of venous thromboembolism: a systematic review Global burden of thrombosis: epidemiologic aspects 30-year mortality after venous thromboembolism: a population-based cohort study The economic burden of incident venous thromboembolism in the United States: a review of estimated attributable healthcare costs Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Role of D-dimers in diagnosis of venous thromboembolism Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Autopsy findings and venous thromboembolism in patients with COVID-19: a prospective cohort study High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Current practice of antibiotic prophylaxis for surgical fixation of closed long bone fractures: a survey of 297 members of the orthopaedic trauma association Prevalence and risk factors of thromboembolism among patients with COVID-19: a protocol for a systematic review and meta-analysis New guidelines for antimicrobial prophylaxis in surgery DVT incidence and risk factors in critically ill patients with COVID-19 Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Thrombotic and hemorrhagic events in critically ill COVID-19 patients: a French monocenter retrospective study Venous thrombosis among critically Ill patients with coronavirus disease 2019 (COVID-19) High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Extremely high incidence of lower extremity deep venous thrombosis in 48 patients with severe COVID-19 in Wuhan Incidence of venous thromboembolism in hospitalized patients with COVID-19 Risk assessment of venous thromboembolism and bleeding in COVID-19 patients Pulmonary embolism in hospitalised patients with COVID-19 Acute pulmonary embolism associated with COVID-19 pneumonia detected by pulmonary CT angiography Acute pulmonary embolism in COVID-19 patients on CT angiography and relationship to D-dimer levels Pulmonary embolism in patients with Covid-19 pneumonia Deep vein thrombosis in hospitalized patients with COVID-19 in Wuhan Systematic assessment of venous thromboembolism in COVID-19 patients receiving thromboprophylaxis: incidence and role of D-dimer as predictive factors Incidence of asymptomatic deep vein thrombosis in patients with COVID-19 pneumonia and elevated D-dimer levels
    keywords: covid-19; events; factors; patients; prevalence; risk; studies; thromboembolism
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        item: #7245 of 7819
          id: cord-348823-u2gm3kyh
      author: Baksh, Mizba
       title: A Systematic Review of Cases of Acute Respiratory Distress Syndrome in the Coronavirus Disease 2019 Pandemic
        date: 2020-05-18
       words: 2255
      flesch: 41
     summary: Novel coronavirus (2019-nCoV) situation report -1 COVID-19) Geographic differences in COVID-19 cases, deaths, and incidence -United States COVIDView: a weekly surveillance summary of U.S. COVID-19 activity Interim clinical guidance for management of patients with confirmed coronavirus disease (COVID-19) Tissue plasminogen activator (tPA) treatment for COVID-19 associated acute respiratory distress syndrome (ARDS): a case series Pathological findings of COVID-19 associated with acute respiratory distress syndrome Rapid progression to acute respiratory distress syndrome: review of current understanding of critical illness from COVID-19 infection Lung involvement found on chest CT scan in a pre-symptomatic person with SARS-CoV-2 infection: a case report The clinical pathology of severe acute respiratory syndrome (SARS): a report from Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding Studies of severe acute respiratory syndrome coronavirus pathology in human cases and animal models Covid-19 -considerations for the paediatric rheumatologist Meta-analysis of preclinical studies of fibrinolytic therapy for acute lung injury Prevention of adult respiratory distress syndrome with plasminogen activator in pigs Severe hypoxemic respiratory failure Salvage therapies for refractory hypoxemia in ARDS Clinical course and mortality risk of severe COVID-19 Higher mortality rate in ventilated COVID-19 patients in large sample Clinical, laboratory and imaging features of COVID-19: a systematic review and meta-analysis Information for clinicians on investigational therapeutics for patients with COVID-19 Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review Brief review on COVID-19: the 2020 pandemic caused by SARS-CoV-2 . There could be a high risk of mortality (about two-thirds) in ventilated patients according to new data from the United Kingdom's Intensive Care National Audit and Research Center (ICNARC), but this was unclear [19] .
    keywords: acute; ards; cases; covid-19; patients; sars
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        item: #7246 of 7819
          id: cord-348835-4ocuw8uk
      author: Aurelio, Mauro
       title: Upper gastrointestinal bleeding in COVID-19 inpatients: Incidence and management in a multicenter experience from Northern Italy
        date: 2020-08-14
       words: 4012
      flesch: 46
     summary: However given the progressive evidence on the risk of thrombosis in this category of patients [5] , thromboprophylaxis was progressively and early started in COVID-19 patients. If patients are more critical (high flow or non-invasive positive pressure support) it is important to stratify them 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 J o u r n a l P r e -p r o o f 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 J o u r n a l P r e -p r o o f 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 Table 1 Clinical characteristics and biochemical data of COVID-19 positive patients with upper 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 J o u r n a l P r e -p r o o f 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 WHO Director-General's opening remarks at the media briefing on COVID-19 -11 Clinical Characteristics of Coronavirus Disease 2019 in China COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis, (in eng) Coronavirus Disease 2019
    keywords: bleeding; covid-19; endoscopy; patients
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        item: #7247 of 7819
          id: cord-348847-53s19r16
      author: Lu, T.
       title: Internet Search Patterns Reveal Clinical Course of Disease Progression for COVID-19 and Predict Pandemic Spread in 32 Countries
        date: 2020-05-06
       words: 3707
      flesch: 50
     summary: For each country and search term, we calculated the Pearson correlation coefficient between the time series of search volumes for that search term and the time series of COVID-19 cases. 42 Another study developed a model incorporating a large selection of search terms, including some symptom-related terms, in 8 countries; however this latter study focused on optimizing the performance of a predictive model, rather than studying the detailed temporal relationships between patterns of symptoms .
    keywords: countries; covid-19; data; license; preprint; search; terms
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        item: #7248 of 7819
          id: cord-348848-js36pw2r
      author: Filut, Amarette
       title: Will Losing Black Physicians Be a Consequence of the COVID-19 Pandemic?
        date: 2020-07-28
       words: 1766
      flesch: 40
     summary: If nothing else, the COVID-19 pandemic must make academic health centers and health care systems recognize Black physicians as the precious resource they are and protect and reward them accordingly. If nothing else, the COVID-19 pandemic must make academic health centers and health care systems recognize Black physicians as the precious resource they are and protect and reward them accordingly.
    keywords: care; covid-19; health; physicians
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        item: #7249 of 7819
          id: cord-348855-lnltoj1n
      author: Iannaccone, Giulia
       title: Weathering the Cytokine Storm in COVID-19: Therapeutic Implications
        date: 2020-06-29
       words: 4681
      flesch: 28
     summary: For these reasons, the WHO does not recommend routine administration of CS in COVID-19 patients outside of clinical trials; their adjunctive use may be indicated on an individual basis or unless indicated for other conditions, such as chronic obstructive pulmonary disease, asthma, and septic shock [23] . Moreover, in 2 small retrospective studies of COVID-19 patients in China suffering from severe lung injury it was observed that the use of this agent could provide significant clinical improvement without important side effects [38, 39] .
    keywords: coronavirus; covid-19; cytokine; disease; infection; patients; response; sars; syndrome; therapy; treatment; use
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        item: #7250 of 7819
          id: cord-348879-opzkodt7
      author: Nune, A.
       title: Challenges in delivering rheumatology care during COVID-19 pandemic
        date: 2020-07-25
       words: 2618
      flesch: 43
     summary: There is little data available about the effect of novel SARS-CoV-2 upon rheumatology patients with autoimmune conditions. Prompt delivery of consistent, clear, unambiguous and specific information directed to rheumatology patients using effective means of communication will reduce helpline queries to a manageable level.
    keywords: care; consultations; covid-19; face; pandemic; patients; rheumatology
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        item: #7251 of 7819
          id: cord-348927-g69gt0oh
      author: Li, Tong
       title: Acute Respiratory Distress Syndrome Treated with Awake Extracorporeal Membrane Oxygenation in a Patient with COVID-19 Pneumonia
        date: 2020-11-10
       words: 1560
      flesch: 43
     summary: After a comprehensive evaluation, she was extubated and received awake ECMO support. In recent years, ECMO without mechanical ventilation (MV) and sedation (awake ECMO) has been utilized in several subset populations.
    keywords: covid-19; ecmo; mmhg; patients
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        item: #7252 of 7819
          id: cord-348941-orpngirf
      author: Torkian, Pooya
       title: Magnetic resonance imaging features of coronavirus disease 2019 (COVID-19) pneumonia: The first preliminary case series
        date: 2020-09-17
       words: 1142
      flesch: 36
     summary: MATERIALS AND METHODS: Upon IRB approval, eight laboratory confirmed COVID-19 patients who presented to our outpatient imaging clinic underwent chest CT and, once various features of COVID-19 pneumonia were identified, a dedicated multisequence chest MRI was performed on the same day with an institutional protocol. There is a rising onus on understanding the common features of COVID-19 pneumonia on different imaging modalities.
    keywords: covid-19; mri; pneumonia
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        item: #7253 of 7819
          id: cord-348963-1faxyx9x
      author: ALHAERY, M.
       title: A COVID-19 Reopening Readiness Index: The Key to Opening up the Economy
        date: 2020-05-26
       words: 3488
      flesch: 52
     summary: Some other states report additional metrics which are not necessarily available in other states. Every state can see the spread in other states and take counter measures if needed.
    keywords: covid-19; data; index; readiness; reopening; state
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        item: #7254 of 7819
          id: cord-348975-plne3xlz
      author: Wagner, Tyler
       title: Augmented curation of clinical notes from a massive EHR system reveals symptoms of impending COVID-19 diagnosis
        date: 2020-07-07
       words: 4950
      flesch: 33
     summary: Expanding beyond one institution's COVID-19 diagnostic testing and clinical care to the EHR databases of other academic medical centers and health systems will provide a more holistic view of clinical symptoms enriched in COVID pos over COVID neg patients in the days preceding confirmed diagnostic testing. Rhinitis is also a potential early signal of COVID pos patients that requires some consideration (2.2-fold amplification, p-value = 2.25E-29).
    keywords: covid; covid pos; covid-19; day; neg; patients; pcr; pcr testing; pos; symptoms; testing
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        item: #7255 of 7819
          id: cord-348976-hgty4t7c
      author: Cai, Yi
       title: Otolaryngology Resident Practices and Perceptions in the Initial Phase of the U.S. COVID‐19 Pandemic
        date: 2020-05-12
       words: 3798
      flesch: 38
     summary: Along with other HCWs directly treating COVID-19 patients, OHNS residents may experience considerable anxiety regarding their personal safety, transmission of the infection, and education. Further follow-up surveys of OHNS residents will be essential to characterize practice patterns, perceptions, and stressors for burnout during the course of the COVID-19 pandemic.
    keywords: attendings; changes; contracting; covid-19; ohns; pandemic; programs; residents; risk
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        item: #7256 of 7819
          id: cord-348999-989vojgu
      author: Boddington, N. L.
       title: COVID-19 in Great Britain: epidemiological and clinical characteristics of the first few hundred (FF100) cases: a descriptive case series and case control analysis
        date: 2020-05-22
       words: 6504
      flesch: 44
     summary: Conclusion: This study presents the first epidemiological and clinical summary of COVID-19 cases in Great Britain. Single variable and multivariable logistic regression were used to calculate odds ratios of each underlying health condition in COVID-19 cases compared to the UK general population, adjusted for sex and age (in categories <18, 18-35, 36-49, 50-69 and ≥ 70 years) as a priori confounders.
    keywords: age; cases; conditions; covid-19; data; disease; ff100; health; infection; population; study
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        item: #7257 of 7819
          id: cord-349008-x750xe8n
      author: Ertl-Wagner, Birgit B.
       title: Preparedness for the COVID-19 pandemic in a tertiary pediatric radiology department
        date: 2020-06-03
       words: 6379
      flesch: 39
     summary: Our processes outlined here are expected to develop Table 4 Checklist for the post-pandemic phase Measures of preparedness in the post-pandemic phase a ✓ Ramp up activities and services in all modalities to appropriate levels ✓ Assess and address radiology inventory needs related to equipment and supplies ✓ Rebook canceled or deferred appointments due to pandemic ✓ Initiate communication and consultations with referring physicians as required ✓ Develop and implement plans to prioritize and address the backlog ✓ Conduct post hoc analysis of the pandemic response and document lessons learned ✓ Improve processes and update pandemic plans as required ✓ Initiate strategic planning for innovative models of diagnostic imaging operations ✓ Recognize and reward teams a Note that this is an abbreviated list as an excerpt from out pandemic preparedness plan and change. Ensure that downtime procedures are up-to-date and available to staff, and re-educate staff ✓ Build infrastructure for video-conferencing and remote interpretation of images ✓ Identify essential resources required to maintain delivery of services ✓ Establish a radiology incident management team (IMT) with clear roles and responsibilities ✓ Coordinate all pandemic planning activities with the hospital IMT ✓ Increase situational awareness and involve staff in the pandemic planning process ✓ Prepare for fully segregated isolation in collaboration with other programs ✓ Determine and prepare for radiology role in the screening and diagnosis of pandemic patients ✓ Create appropriate warning and room access control signage ✓ Define activities that will be maintained during the pandemic and activities that will have to be discontinued ✓ Establish a plan to manage staff absenteeism and to address service gaps ✓ Complete an accurate skill set inventory for all non-physician staff ✓ Identify opportunities for staff redeployment and designate back-ups for key roles ✓ Designate rooms for rapid isolation of suspected cases and specify process steps ✓ Determine standardized protocol for decontamination of equipment and imaging rooms ✓ Develop pandemic communication plan and build redundancy into communications ✓ Identify staff members that are particularly vulnerable to the pandemic a Note that this is an abbreviated list as an excerpt from our pandemic preparedness plan.
    keywords: covid-19; department; examinations; hospital; imaging; pandemic; patients; ppe; preparedness; radiology; situation; staff
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        item: #7258 of 7819
          id: cord-349031-tbof9yqi
      author: Chen, Shiu-Jau
       title: Novel Antiviral Strategies in the Treatment of COVID-19: A Review
        date: 2020-08-20
       words: 5473
      flesch: 38
     summary: Nord experience Clinical trials on drug repositioning for COVID-19 treatment COVID-19 pandemic: An overview of epidemiology, parthenogenesis, diagnostics and potential vaccines and therapeutics Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, single-blind, randomized controlled trial Inhibition of cytokine signaling by ruxolitinib and implications for COVID-19 treatment Convalescent plasma in Covid-19: Possible mechanisms of action Treatment of 5 critically Ill patients with COVID-19 with convalescent plasma Effectiveness of convalescent plasma therapy in severe COVID-19 patients Anti-SARS-CoV-2 virus antibody levels in convalescent plasma of six donors who have recovered from COVID-19 Treatment with convalescent plasma for COVID-19 patients in Wuhan Use of convalescent plasma therapy in two COVID-19 patients with acute respiratory distress syndrome in Korea Deployment of convalescent plasma for the prevention and treatment of COVID-19 Convalescent plasma transfusion for the treatment of COVID-19: Systematic review Potential application of the CRISPR/Cas9 system against herpesvirus infections Gene editing technologies and Applications Opioid addiction, genetic susceptibility and medical treatments: A Review Development of CRISPR as an antiviral strategy to combat SARS-CoV-2 and influenza Mesenchymal stem cell therapy for COVID-19: Present or future Current status of cell-based therapies for respiratory virus infections: Applicability to COVID-19 Transplantation of ACE2-Mesenchymal stem cells improve the outcome of patients with COVID-19 pneumonia Expanded umbilical cord mesenchymal stem cells (UC-MSCs) as a therapeutic strategy in managing critically Ill COVID-19 patients: The case for compassionate use Convalescent plasma therapy for persistent hepatitis E virus infection Convalescent plasma new evidence for an old therapeutic tool Feasibility of using convalescent plasma immunotherapy for MERS-CoV infection, Saudi Arabia Use of convalescent plasma in Ebola virus infection Experience of using convalescent plasma for severe acute respiratory syndrome among healthcare workers in a Taiwan hospital Use of convalescent plasma therapy in SARS patients in Hong Kong Convalescent plasma as a potential therapy for COVID-19 Collecting and evaluating convalescent plasma for COVID-19 treatment: In this review, we explore the applications, possible mechanisms, and efficacy in successful cases using convalescent plasma, CRISPR, and MSC therapy for COVID-19 treatment, respectively.
    keywords: cells; convalescent; convalescent plasma; covid-19; disease; efficacy; patients; plasma; sars; therapy; treatment; use
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        item: #7259 of 7819
          id: cord-349078-59wel5o5
      author: Kanniah, Kasturi Devi
       title: COVID-19's impact on the atmospheric environment in the Southeast Asia region
        date: 2020-05-25
       words: 5862
      flesch: 33
     summary: As a result of the lockdown and the disruption in human and industrial activities in numerous countries around the world, a significant reduction in air pollution, especially in the concentration of NO 2 , has been noticed in China and several European and American countries (Shrestha et al., 2020; Tobias et al., 2020; Wang and Su, 2020; Zhang et al., 2020) . A qualitative overview shows that the SEA pollution outflow (Wang et al., 2015) over the oceanic regions has been reduced during 2020, compared to the previous years, as also observed over the southern China Sea due to restriction measures and the general lockdown in China Wang and Su, 2020) .
    keywords: air; covid-19; et al; levels; lockdown; pollution; urban
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        item: #7260 of 7819
          id: cord-349095-fnlgm4dv
      author: Youssef, Sofian
       title: First impressions of the foundation interim year 1 postings: positives, pitfalls, and perils
        date: 2020-06-25
       words: 1012
      flesch: 42
     summary: Foundation doctors work under vastly varied rotas, notably the new emergency COVID-19 rotas, that is incompatible with that of FiY1s. This has radically reduced the workload for junior doctors and the department as a whole.
    keywords: covid-19; doctors; fiy1
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        item: #7261 of 7819
          id: cord-349104-p0egfpx9
      author: Modi, Anita R.
       title: Coronavirus disease 2019 in an orthotopic liver transplant recipient living with human immunodeficiency virus
        date: 2020-06-17
       words: 1210
      flesch: 27
     summary: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice COVID-19 in solid organ transplant recipients: initial report from the US Epicenter COVID-19 and kidney transplant patients COVID-19 in long-term liver transplant patients: preliminary experience from an italian transplant center in Lombardy COVID-19 in Patients with HIV: Clinical Case Series Outcomes of Kidney Transplantation in HIV-infected Recipients COVID-19 Illness in Native and Immunosuppressed States: A Clinical-Therapeutic Staging Proposal Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Observational study of hydroxychloroquine in hospitalized patients with COVID-19 Coronavirus disease 2019 in an orthotopic liver transplant recipient living with human immunodeficiency virus Yet immunocompromised status alone, in the absence of other comorbidities, may not necessarily predict severe illness presentations and poorer clinical outcomes as indicated by recent reports of COVID‐19‐infected solid organ transplant recipients and people living with human immunodeficiency virus (HIV).
    keywords: covid-19; hiv; liver; transplant
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        item: #7262 of 7819
          id: cord-349124-nhnl7zgi
      author: de Sandes‐Freitas, Tainá Veras
       title: Lessons from SARS‐CoV‐2 screening in a Brazilian organ transplant unit
        date: 2020-07-13
       words: 1197
      flesch: 36
     summary: We also do not know if asymptomatic carrier transplant recipients have higher risk to develop symptoms when compared to the general population. From this event, all newly admitted patients have been tested for COVID-19 and maintained isolated from other patients until the test result is known.
    keywords: asymptomatic; covid-19; patients; symptoms
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        item: #7263 of 7819
          id: cord-349144-cvmebr3f
      author: Barca, Ida
       title: Telemedicine in Oral and Maxillo-Facial Surgery: An Effective Alternative in Post COVID-19 Pandemic
        date: 2020-10-09
       words: 4864
      flesch: 34
     summary: The experience acquired by the authors during the COVID-19 pandemic suggests that telemedicine is indicated above all in the follow-up of cancer patients, because they are immunosuppressed for previous chemo/radiation treatments and therefore subject to greater risk of contagion, in chronic as well as urgent visits for suspected malignancy and in patients who live far from a hospital. From the experience acquired by the authors during the COVID-19 pandemic, it emerged that TM is indicated above all in the follow-up of cancer patients, because they are immunosuppressed for previous chemo/radiation treatments and therefore subject to greater risk of contagion, and chronic as well as urgent visits for suspected malignancy [10] .
    keywords: consultation; covid-19; group; health; pandemic; patients; photos; surgery; telemedicine
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        item: #7264 of 7819
          id: cord-349159-rndtf508
      author: Brosseau, Lisa M
       title: Selecting Controls for Minimizing SARS-CoV-2 Aerosol Transmission in Workplaces and Conserving Respiratory Protective Equipment Supplies
        date: 2020-08-21
       words: 5952
      flesch: 39
     summary: Guidance from the European Agency for Safety and Health at Work (2020) notes the importance of applying the hierarchy of controls, starting with eliminating the risk followed by minimizing worker exposure and finally personal protective equipment. Daily duration (number of potential exposure hours per 8 h workday) Examples of source controls might be: • Eliminate all in-person interactions by requiring customers to conduct their business via phone, internet, or some remote method, in combination with delivery or drive-by pickup.
    keywords: air; controls; covid-19; exposure; particles; pathway; risk; source; transmission; workers
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        item: #7265 of 7819
          id: cord-349198-mx5pu9fq
      author: Sverzellati, Nicola
       title: Integrated Radiologic Algorithm for COVID-19 Pandemic
        date: 2020-04-07
       words: 1679
      flesch: 33
     summary: Flowchart A, CT diagnostic categories in the COVID-19 protocol. The classification of CT findings was defined by 3 major categories: (1) Negative for COVID-19.
    keywords: category; covid-19; disease
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        item: #7266 of 7819
          id: cord-349210-8t4a5qqo
      author: Ji, Ping
       title: Immunomodulatory Therapeutic Proteins in COVID‐19: Current Clinical Development and Clinical Pharmacology Considerations
        date: 2020-08-10
       words: 7716
      flesch: 34
     summary: About 5-10% of COVID-19 patients developed lung injury and respiratory distress that progressed to acute respiratory distress syndrome (ARDS). A minority of COVID-19 patients will transition into the severe and critical stages of the illness, which manifest as an extrapulmonary systemic hyperinflammation syndrome.
    keywords: clinical; cov-2; covid-19; disease; dose; dosing; infection; patients; pneumonia; proteins; risk; sars; treatment; trial
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        item: #7267 of 7819
          id: cord-349226-xzlc1pni
      author: Khatiwada, Saroj
       title: Lung microbiome and coronavirus disease 2019 (COVID-19): possible link and implications
        date: 2020-08-05
       words: 4317
      flesch: 31
     summary: The COVID-19 disease begins with the invasion of lungs by SARS-CoV-2 virus, and the major complications that develop subsequently are related to lung infection and immune response generation, therefore, lung microbiome might play an important role from initiation to the progression of this disease [16] . In lung diseases, these factors can change, and therefore overgrowth of one species with reduction of microbial diversity occurs (shown in figure 1 )
    keywords: cells; covid-19; disease; immunity; infection; lung; microbiome; patients; pneumonia; sars
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        item: #7268 of 7819
          id: cord-349263-mmfrqyrc
      author: Rodríguez, A.
       title: Severe infection due to the SARS-CoV-2 coronavirus: Experience of a tertiary hospital with COVID-19 patients during the 2020 pandemic
        date: 2020-11-09
       words: 4184
      flesch: 52
     summary: Patients Patients admitted due to COVID-19 and respiratory failure. key: cord-349263-mmfrqyrc authors: Rodríguez, A.; Moreno, G.; Gómez, J.; Carbonell, R.; Picó-Plana, E.; Benavent Bofill, C.; Sánchez Parrilla, R.; Trefler, S.; Esteve Pitarch, E.; Canadell, L.; Teixido, X.; Claverias, L.; Bodí, M. title: Severe infection due to the SARS-CoV-2 coronavirus: Experience of a tertiary hospital with COVID-19 patients during the 2020 pandemic date: 2020-11-09 journal: nan DOI: 10.1016/j.medine.2020.05.005 sha: doc_id: 349263 cord_uid: mmfrqyrc Objective To describe the clinical and respiratory characteristics of a cohort of 43 patients with COVID-19 after an evolutive period of 28 days.
    keywords: admission; covid-19; days; icu; imv; mortality; patients; rate; study
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        item: #7269 of 7819
          id: cord-349276-viq01q8l
      author: Shaw, Rajib
       title: Governance, technology and citizen behavior in pandemic: Lessons from COVID-19 in East Asia
        date: 2020-04-30
       words: 9228
      flesch: 50
     summary: Here, a few critical issues on Japan's approach is described below: Diamond Princess Experiences: The Cruise ship Diamond princess arrived at the port of Yokohama on 3rd February 2020 and received world attention due to reported confirmed case in the ship. China sees a sharp increase in number of confirmed cases from the third week of January, while a sharp increase in both recovered and death from the first week of February.
    keywords: cases; china; control; countries; covid-19; disease; february; government; health; january; japan; korea; march; people; self; spread; virus; wuhan
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        item: #7270 of 7819
          id: cord-349297-de6vwlh5
      author: Chow, D. S.
       title: The disproportionate rise in COVID-19 cases among Hispanic/Latinx in disadvantaged communities of Orange County, California: A socioeconomic case-series
        date: 2020-05-07
       words: 3540
      flesch: 42
     summary: https://doi.org/10.1101/2020.05.04.20090878 doi: medRxiv preprint Coronavirus COVID-19 Global Cases by the Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease COVID-19 and African Americans COVID-19 fatalities The social determinants of health: it's time to consider the causes of the causes Social determinants and non-communicable diseases: time for integrated action Life course approach to prevention and control of non-communicable diseases Addressing social determinants of health in the prevention and control of HIV/AIDS, viral hepatitis, sexually transmitted infections, and tuberculosis Social determinants of influenza hospitalization in the United States. It is widely accepted that social determinants of health, conditions in which people are born, grow, work, live, age, and the wider set of forces and systems, 5 play a critical role in the creation of disparities related to morbidity, mortality, and quality of life for most chronic, noncommunicable diseases (NCD's) including cardiovascular disease, stroke, diabetes, asthma, and certain cancers 6 .
    keywords: author; covid-19; disparities; medrxiv; preprint; race; review
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        item: #7271 of 7819
          id: cord-349313-2gupfqnl
      author: Martinez-Perez, Clara
       title: Citation Network Analysis of the Novel Coronavirus Disease 2019 (COVID-19)
        date: 2020-10-21
       words: 7155
      flesch: 48
     summary: Alterations in the digestive system as a result of COVID-19 Blood clotting alterations in COVID-19 patients. It has been shown that digestive symptoms are common in COVID-19 patients.
    keywords: analysis; citation; coronavirus; cov-2; covid-19; disease; group; number; patients; publications; research; sars
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        item: #7272 of 7819
          id: cord-349329-f0pbd968
      author: Bosteels, Cedric
       title: Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial
        date: 2020-06-05
       words: 12419
      flesch: 40
     summary: The study will be conducted cfr the latest version of the ICH E6 (R2) GCP guidelines, creating a standard for the design, conduct, performance, monitoring, auditing, recording, analyses and reporting of clinical studies that provides assurance that the data and reported results are accurate and that the rights, integrity and confidentiality of study subjects are protected. Monitoring services will consist of the following (non-exhaustive list): -review of informed consents and the followed process -check on recruitment status -checking for protocol deviations/violations -checking GCP compatibility -check on safety reporting compliance -IMP handling and storage -review of study data … This study can be inspected at any time by regulatory agencies during or after completion of the study.
    keywords: acute; ards; blood; covid-19; csf; data; day; days; failure; group; intervention; leukine; lung; patients; period; sargramostim; study; subject; treatment
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        item: #7273 of 7819
          id: cord-349353-2ll9hzfr
      author: Giordano, Chiara
       title: Freedom or money? The dilemma of migrant live‐in elderly carers in times of COVID‐19
        date: 2020-07-04
       words: 7542
      flesch: 42
     summary: The fact that the main qualities (or 'soft skills') which are usually requested and appreciated in elderly carers are the ability to establish emotional ties, empathy, humanity, as well as a sort of vocation, testifies of the importance of the emotional dimension in care work (Anderson, 2000) . Specifically, I look at their 'identity locations' as women, as migrants, as elderly care workers, as family breadwinners, and as 'quasi-family members' in their employing families, which are in turn related to larger domains of power (namely gender, ethnicity/citizenship, labour market, care economy and interpersonal power relations, respectively).
    keywords: care; caregivers; carers; covid-19; families; family; live; lockdown; women; work; working
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        item: #7274 of 7819
          id: cord-349355-k48s9sum
      author: Janssen, Joris
       title: Spontaneous pneumomediastinum in a male adult with COVID-19 pneumonia
        date: 2020-07-30
       words: 960
      flesch: 36
     summary: Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV) Coronavirus Disease 2019 (COVID-19): Role of Chest CT in Diagnosis and Management Spontaneous pneumomediastinum in H1N1 infection: uncommon complication of a common infection Pneumomediastinum in a patient with pneumocystis jirovecii pneumonia Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study Spontaneous pneumomediastinum occurring in the SARS-COV-2 infection Mediastinal Emphysema, Giant Bulla, and Pneumothorax Developed during the Course of COVID-19 Pneumonia COVID-19 with spontaneous pneumomediastinum. Here we present a case of spontaneous pneumomediastinum in COVID-19 pneumonia, and discuss the possible mechanism underlying this association as well as clinical implications.
    keywords: covid-19; pneumomediastinum; pneumonia
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        item: #7275 of 7819
          id: cord-349360-dv4lxx52
      author: Cozza, Valerio
       title: I-ACTSS-COVID-19—the Italian acute care and trauma surgery survey for COVID-19 pandemic outbreak
        date: 2020-06-24
       words: 3436
      flesch: 44
     summary: Likely, the caseload was a crucial factor, together with resources availability, for choosing to admit suspected and confirmed COVID-19 patients to specific surgical wards or in mixed medical and surgical COVID + wards. This survey shows a strong interest on the part of acute care surgeons, involved as first line operators in managing the pathways of suspected and confirmed patients and often directly treating COVID-19 patients.
    keywords: care; covid-19; emergency; patients; surgery; trauma
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        item: #7276 of 7819
          id: cord-349408-2ser9zjc
      author: Iannuzzi, Nicholas P.
       title: An Orthopaedic Department’s Response to the COVID-19 Health-Care Crisis: Indirect and Direct Actions with Thoughts for the Future
        date: 2020-05-05
       words: 2257
      flesch: 36
     summary: We consider direct actions to be those taken in addition to our normal practice-actions involving direct patient care but performed outside of the usual setting. COVID-19 guidelines for triage of orthopaedic patients COVID-19-new insights on a rapidly changing epidemic Care for critically ill patients with COVID-19 Trump wants to 'reopen America Coronavirus math shows the importance of social distancing, and the horrible consequences of not doing it Effects of the length of stay on the cost of total knee and total hip arthroplasty from 2002 to 2013 Inpatient consults and complications during primary total joint arthroplasty in a bundled care model Managing resident workforce and education during the COVID-19 pandemic
    keywords: care; covid-19; health; orthopaedic; patients
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        item: #7277 of 7819
          id: cord-349415-q0g0uqj6
      author: Commodari, Elena
       title: Adolescents in Quarantine During COVID-19 Pandemic in Italy: Perceived Health Risk, Beliefs, Psychological Experiences and Expectations for the Future
        date: 2020-09-23
       words: 6996
      flesch: 44
     summary: Hypothesis 3 (H3): Other sociodemographic variables influence health risk perception and psychological experiences of the adolescents in the sample. In both cases, the medium effect size suggests a role of these variables in influencing health risk perception.
    keywords: adolescents; covid-19; feelings; measures; participants; perception; quarantine; risk; study
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        item: #7278 of 7819
          id: cord-349418-98sgr5iv
      author: Bo, Yacong
       title: Effectiveness of non-pharmaceutical interventions on COVID-19 transmission in 190 countries from 23 January to 13 April 2020
        date: 2020-10-29
       words: 4194
      flesch: 43
     summary: Association Between Statewide School Closure and COVID-19 Incidence and Mortality in the US The role of community-wide wearing of face mask for control of coronavirus disease 2019 (COVID-19) epidemic due to SARS-CoV-2 The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak Physical distancing, face masks, and eye protection to prevent person-to-person transmission of SARS-CoV-2 and COVID-19: a systematic review and meta-analysis A new framework and software to estimate time-varying reproduction numbers during epidemics Impact assessment of non-pharmaceutical interventions against coronavirus disease 2019 and influenza in Hong Kong: an observational study Effects of nonpharmaceutical interventions on COVID-19 cases, deaths, and demand for hospital services in the UK: a modelling study An interactive web-based dashboard to track COVID-19 in real time Serial Interval of COVID-19 among Publicly Reported Confirmed Cases To mask or not to mask: If any NPI of a type was deemed officially announced as being in force at a site on any day of the study period, that NPI type was treated as 'on' for that site on that day in our data J o u r n a l P r e -p r o o f analysis.
    keywords: covid-19; distancing; mask; npis; quarantine; study; traffic
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        item: #7279 of 7819
          id: cord-349428-i2s41kl7
      author: Griffin, Ian
       title: The Impact of COVID-19 Infection on Labor and Delivery, Newborn Nursery, and Neonatal Intensive Care Unit: Prospective Observational Data from a Single Hospital System
        date: 2020-06-13
       words: 4433
      flesch: 49
     summary: Two separate, designated spaces were established in the NICU for newborn infants under investigation depending on whether they did or did not have respiratory distress. Parent visitation was not allowed for newborn infants in the NICU isolation rooms who were born to mothers with COVID-19 or who were PUIs.
    keywords: cov-2; covid-19; infants; isolation; mother; newborn; sars; testing
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        item: #7280 of 7819
          id: cord-349439-3z0b77r5
      author: Mandal, Amitabha
       title: A Systematic Review on Tracheostomy in COVID-19 Patients: Current Guidelines and Safety Measures
        date: 2020-09-28
       words: 2497
      flesch: 47
     summary: In this review various international guidelines and sources were put together, and we aim to summarize in a systematic way the available recommendations: indications, timing, technique and safety measures for tracheostomy for COVID-19 patients, from all over the world. However there are no current guidelines regarding the optimal time of tracheostomy in COVID-19 patients but most of the European countries following local policy of 14 days before performing tracheostomy.
    keywords: care; coronavirus; covid-19; pandemic; patients; procedure; tracheostomy
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        item: #7281 of 7819
          id: cord-349445-yh6ndtgm
      author: Mohammed El Tabaa, Manar
       title: Targeting Neprilysin (NEP) pathways: A potential new hope to defeat COVID-19 ghost
        date: 2020-05-27
       words: 11864
      flesch: 29
     summary: As well, NEP could not affect lung Ang (1-7) metabolism because it was involved in the metabolism of Ang (1-7) within tissues other than pulmonary tissues, as renal cortex. Subsequently, RAS exhibits two main axes based on two distinct enzymes responsible for cleavage of Ang I into angiotensin (Ang) II or Ang 1-7 [51] , First axis involves generation of Ang II as the main effector via the angiotensin converting enzyme (ACE) and named the classical vasopressor axis ACE/ Ang II/ Ang II type 1 receptor (AT1)
    keywords: ang; angiotensin; cells; clinical; coronavirus; cov-2; covid-19; disease; endothelial; enzyme; injury; lung; nep; patients; peptide; pulmonary; ras; receptor; role; sars; system; treatment
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        item: #7282 of 7819
          id: cord-349474-pprxwij6
      author: Elshami, Wiam
       title: The radiology workforce’s response to the COVID-19 pandemic in the Middle East, North Africa and India
        date: 2020-09-23
       words: 4718
      flesch: 40
     summary: Baseline chest x-ray showed a sensitivity of 69% in COVID-19 infection and imaging follow-up (54) ; chest CT has a limited but important role in the clinical management of COVID-19 patients (50) . The respondents reported experiences of work-related stress (42.9%), high COVID-19 fear score (83.3%) and anxiety (10%) during the study period.
    keywords: anxiety; covid-19; fear; health; pandemic; radiology; score; stress; study; work
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        item: #7283 of 7819
          id: cord-349477-3qhpu7v0
      author: Jarynowski, A.
       title: An attempt to optimize human resources allocation based on spatial diversity of COVID-19 cases in Poland
        date: 2020-10-15
       words: 7012
      flesch: 40
     summary: We recommend that during the next wave of infections, Polish Sanitary Inspection should be strengthened in terms of staff and IT services in high risk poviats. others (2020). w polsce przy pomocy modeli matematycznych i uczenia maszynowego Exploring the spatial concentration of foreign employment in poland under the simplified procedure Ranking the effectiveness of worldwide covid-19 government interventions Badanie kosztowej-efektywnoÅci interwencji mitygujÄcych ryzyko zakazen covid-19 przed fala jesienna Obliczeniowe nauki spoleczne w praktycze Niewykorzystany potencjał systemów informatycznych w epidemiologii zakażeń szpitalnych w polsce Socio-economic models of divorces in different societies Modelling communities and populations: an introduction to computational social science Percepcja âkoronawirusaâ w polskim internecie do czasu potwierdzenia pierwszego przypadku zakażenia sars-cov-2 w polsce Trends in interest of covid-19 on polish internet Social values are significant factors in control of covid-19 pandemic-preliminary results Attempt to understand public health relevant social dimensions of covid-19 outbreak in poland Mobilność jako kluczowa zmienna wyjaśniająca regionalne różnice w dynamice zakażeń-wyniki wstępne Prognozy rozwoju epidemii koronawirusa Population flow drives spatio-temporal distribution of covid-19 in china others (2020).
    keywords: arrival; cases; covid-19; data; et al; infections; level; license; mobility; number; poland; population; poviats; preprint; sars; size; variables
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        item: #7284 of 7819
          id: cord-349500-603v8lfb
      author: Neurath, Markus F
       title: Covid-19 and immunomodulation in IBD
        date: 2020-04-16
       words: 6564
      flesch: 37
     summary: In contrast, another study reported that covid-19 ICU patients had significantly higher serum levels of TNF than non-ICU patients. Therefore, this review will address the following questions: ► What is the evidence for intestinal covid-19 disease and how does covid-19 induce mucosal immune cell activation and a cytokine release syndrome?
    keywords: ace2; cell; clinical; coronavirus; cov-2; covid-19; cytokine; disease; ibd; patients; sars; syndrome; therapy
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        item: #7285 of 7819
          id: cord-349558-vof63qat
      author: Jain, Vageesh
       title: Systematic review and meta-analysis of predictive symptoms and comorbidities for severe COVID-19 infection
        date: 2020-03-16
       words: 4506
      flesch: 47
     summary: Figure 2 illustrates the proportion of included studies which met each individual appraisal indicator. The clinical spectrum of COVID−19 disease is varied, and identifying factors associated with severe disease has been described as an urgent research priority.
    keywords: comorbidities; disease; icu; medrxiv; preprint; studies; symptoms
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        item: #7286 of 7819
          id: cord-349565-g1emvmdu
      author: Conti, Clara Benedetta
       title: Bleeding in COVID-19 severe pneumonia: The other side of abnormal coagulation pattern?
        date: 2020-05-07
       words: 1329
      flesch: 41
     summary: In the available studies, COVID-19 patients showed alterations of coagulation test, with significant increase of D-Dimer levels associated with severity of illness and adverse outcomes (2). If on one hand the protrombotic features have been underlined and few reports about minor or obscure/occult GI bleeding appeared in literature, up to now no major internal bleeding have been observed in COVID-19 patients.
    keywords: artery; bleeding; covid-19; patients
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        item: #7287 of 7819
          id: cord-349566-zx9kt144
      author: de Alencar, Julio Cesar Garcia
       title: Double-blind, randomized, placebo-controlled trial with N-acetylcysteine for treatment of severe acute respiratory syndrome caused by COVID-19
        date: 2020-09-23
       words: 2959
      flesch: 48
     summary: We hypothesized that N-acetylcysteine (NAC) administration could restore this redox homeostasis and suppress unfavorable evolution in Covid-19 patients. It is necessary, therefore, to discuss the causes of this treatment failure in improving respiratory function in Covid-19 patients.
    keywords: angii; angiotensin; covid-19; nac; patients; placebo; redox
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        item: #7288 of 7819
          id: cord-349618-s85oi17h
      author: Dziedzic, Arkadiusz
       title: Challenges of Oral Medicine Specialistsat the time of COVID‐19 Pandemic
        date: 2020-07-02
       words: 2034
      flesch: 25
     summary: The clinical use of these additional measures could play an important role especially in the management of medically compromised individuals, who compose a major group of OM patients. There is no specific and universal guideline for the personal protective equipment (PPE) use dealing with OM procedures in COVID-19 positive/negative cases.
    keywords: care; covid-19; et al; oral; patients
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        item: #7289 of 7819
          id: cord-349645-6o8773c5
      author: Li, He
       title: Air Pollution and temperature are associated with increased COVID-19 incidence: a time series study
        date: 2020-06-02
       words: 3019
      flesch: 42
     summary: As the SARS-CoV-2 has a median incubation period of 4 days in human (Guan et al., 2020) , all independent variables were used to fit daily COVID-19 incidence from 4 days later. Interestingly, all ambient air pollutants showed positive association with daily COVID-19 incidence.
    keywords: air; covid-19; incidence; study
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        item: #7290 of 7819
          id: cord-349646-imv0sc9y
      author: Lee, Yonghyun
       title: Prevalence and Duration of Acute Loss of Smell or Taste in COVID-19 Patients
        date: 2020-05-06
       words: 1570
      flesch: 44
     summary: key: cord-349646-imv0sc9y authors: Lee, Yonghyun; Min, Pokkee; Lee, Seonggu; Kim, Shin-Woo title: Prevalence and Duration of Acute Loss of Smell or Taste in COVID-19 Patients date: 2020-05-06 journal: J Korean Med Sci DOI: 10.3346/jkms.2020.35.e174 sha: doc_id: 349646 cord_uid: imv0sc9y Initially, acute loss of smell (anosmia) and taste (ageusia) was not considered important symptoms for coronavirus disease 2019 (COVID-19). 10-13 From March 8, 2020, DMA physicians prospectively questioned patients newly diagnosed with COVID-19 who were awaiting hospitalization or facility isolation regarding the presence of anosmia or ageusia; they also provided counseling on a daily basis for these symptoms until admission to hospitals or therapeutic living centers.
    keywords: ageusia; anosmia; covid-19; patients
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        item: #7291 of 7819
          id: cord-349678-79zlgjqi
      author: Warrior, Krishnan
       title: Acute Limb Ischemia Due to Arterial Thrombosis Associated With Coronavirus Disease 2019
        date: 2020-06-11
       words: 2535
      flesch: 43
     summary: A recently published cohort study from Lombardy, Italy, demonstrated a higher-than-expected incidence of ALI due to arterial thrombosis in COVID-19 pneumonia patients (12) . The most common etiology of ALI is cardiac embolization, particularly in patients without preexisting peripheral arterial disease (13) .
    keywords: arterial; artery; covid-19; dimer; disease; patients; thrombosis
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        item: #7292 of 7819
          id: cord-349682-kpg0vley
      author: Ojha, Probir Kumar
       title: Therapeutics for COVID-19: from computation to practices—where we are, where we are heading to
        date: 2020-09-02
       words: 7951
      flesch: 40
     summary: Repurposing drugs against main protease of SARS-CoV-2: mechanism based insights supported by available laboratory and clinical data Identification of potential inhibitors of SARS-CoV2 main protease via a rapid in-silico drug repurposing approach In silico screening of Chinese herbalmedicines with the potential to directly inhibit 2019 novel coronavirus Analysis of therapeutic targets for SARS-CoV2 and discovery of potential drugs by computational methods Predicting commercially available antiviral drugs that may act on the novel coronavirus (SARS-CoV2) through a drug-target interaction deep learning model Computational search for potential COVID-19 drugs from FDA-approved drugs and small molecules of natural origin identifies several anti-virals and plant products Identification of SARS-CoV2 cell entry inhibitors by drug repurposing using in silico structure-based virtual screening approach Prediction of the SARS-CoV2 (2019-nCoV) 3C-like protease (3CL pro ) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates Comparative computational study of SARS-CoV2 receptors antagonists from already approved drugs Investigation into SARS-CoV-2 resistance of compounds in garlic essential oil In-silico studies of antimalarialagent artemisinin and derivatives portray more potent binding to Lys353 and Lys31-binding hotspots of SARS-CoV2 spike protein than hydroxychloroquine: potential repurposing of artenimol for COVID-19 Structural and molecular modelling studies reveal a new mechanism of action of chloroquine and hydroxychloroquine against SARS-CoV2 infection Destabilizing the structural integrity of SARS-CoV2 receptor proteins by curcumin along with hydroxychloroquine: an insilco approach for a combination therapy Identification of potential molecules against COVID-19 main protease through structure-guided virtual screening approach Development of a simple, interpretable and easily transferable QSAR model for quick screening antiviral databases in search of novel 3Clike protease (3CLpro) enzyme inhibitors against SARS-CoV diseases Computational screening for potential drug candidates against the SARS-CoV-2 main protease Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease Protein reliability analysis and virtual screening of natural inhibitors for SARS-CoV-2 main protease (Mpro) through docking, molecular mechanic & dynamic, and ADMET Profiling. Table 1 Drug candidates under trial against COVID-19 with probable targets, mechanism of action, pathophysiology, application and current status [11, 12, 14, 30, 40, 43, 45, 53, 55, Drug candidates under trial The SARS-CoV-2 uses the S protein to facilitate viral entry into the host cells.
    keywords: ace2; cell; clq; coronavirus; cov-2; covid-19; drug; fig; host; human; inhibitors; patients; potential; protease; protein; receptor; sars; treatment; trial
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        item: #7293 of 7819
          id: cord-349696-w3ajpaxo
      author: Yıldız, Erman
       title: What can be said about lifestyle and psychosocial issues during the coronavirus disease pandemic? first impressions
        date: 2020-07-06
       words: 1274
      flesch: 35
     summary: As this situation will inevitably have serious effects on mental health by increasing unemployment, lack of financial security and poverty, it is clear that pandemic management requires socioeconomic policies. The psychological impact of quarantine and how to reduce it: rapid review of the evidence Quarantine, isolation and the duty of easy rescue in public health Considerations for quarantine of individuals in the context of containment for coronavirus disease (COVID-19 Lifestyle modification with physical activity promotion on leptin resistance and quality of life in metabolic syndrome-a systematic review with meta-analysis Lifestyle indices and cardiovascular disease risk: a meta-analysis Lifestyle at time of COVID-19: how could quarantine affect cardiovascular risk Ineffectiveness of commercial weight-loss programs for achieving modest but meaningful weight loss: systematic review and meta-analysis Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science.
    keywords: covid-19; health; lifestyle; pandemic
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        item: #7294 of 7819
          id: cord-349740-xed4aybr
      author: Wang, Yulong
       title: Recommendations of protective measures for orthopedic surgeons during COVID-19 pandemic
        date: 2020-06-10
       words: 4271
      flesch: 45
     summary: After screening for COVID-19 (Table 3) , COVID-19 negative patients can be transferred to the general ward in a single room, minimizing the number of family caregivers (at most 1 member) and forbidding other family members to visit [30, 39] . Lessons learnt from our experience provide some recommendations of protective measures during the entire diagnosis and treatment process of traumatic patients and help others to manage orthopedic patients with COVID-19, to reduce the risk of cross-infection between patients and to protect healthcare workers during work.
    keywords: covid-19; emergency; infection; measures; orthopedic; pandemic; patients; room; surgery; treatment
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        item: #7295 of 7819
          id: cord-349755-81ijzz3a
      author: Perz, Catherine A.
       title: Validation of the Fear of COVID-19 Scale in a US College Sample
        date: 2020-06-25
       words: 3033
      flesch: 47
     summary: The results of the present study also illuminate additional aspects of the predictors of COVID-19 anxiety. key: cord-349755-81ijzz3a authors: Perz, Catherine A.; Lang, Brent A.; Harrington, Rick title: Validation of the Fear of COVID-19 Scale in a US College Sample date: 2020-06-25 journal: Int J Ment Health Addict DOI: 10.1007/s11469-020-00356-3 sha: doc_id: 349755 cord_uid: 81ijzz3a The COVID-19 pandemic has impacted college students’ coursework, stress levels, and perceived health.
    keywords: anxiety; covid-19; fear; scale
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        item: #7296 of 7819
          id: cord-349757-lhdkps01
      author: Barba, Maddalena
       title: Cancer patients and coronavirus disease 2019: evidence in context
        date: 2020-08-15
       words: 1866
      flesch: 37
     summary: Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Risk of COVID-19 for cancer patients Time to initiation of adjuvant chemotherapy in patients with rapidly proliferating early breast cancer The experience on coronavirus disease 2019 and cancer from an oncology hub institution in Milan, Lombardy Region Implications of SARS-CoV-2 Infection and COVID-19 Crisis on Clinical Cancer Care: Report of the University Cancer Center Hamburg Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy Controversies about COVID-19 and anticancer treatment with immune checkpoint inhibitors Excess mortality from COVID-19: a commentary on the Italian experience Covid-19 and smoking: a SR of the evidence Palliative care for patients with cancer in the Covid-19 There are no acknowledgements to declare. key: cord-349757-lhdkps01 authors: Barba, Maddalena; Krasniqi, Eriseld; Ciliberto, Gennaro; Vici, Patrizia title: Cancer patients and coronavirus disease 2019: evidence in context date: 2020-08-15 journal: J Transl Med DOI: 10.1186/s12967-020-02483-w sha: doc_id: 349757 cord_uid: lhdkps01 In the rapidly evolving coronavirus disease 2019 (COVID-19) outbreak, inherent literature has been increasing at an impressive rate.
    keywords: cancer; care; covid-19; disease; patients
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        item: #7297 of 7819
          id: cord-349786-12lc3342
      author: Acquah, Samuel
       title: Implications of COVID-19 Pandemic on Evolution of Diabetes in Malaria-Endemic African Region
        date: 2020-10-08
       words: 3437
      flesch: 37
     summary: This is premised upon mild inflammation associated with mild cases of COVID-19 infection, which can cause insulin resistance and increase the risk for development of T2DM. Use of ACE2 by the COVID-19 virus induces inflammation and oxidative stress, which can lead to insulin resistance.
    keywords: angiotensin; covid-19; diabetes; insulin; malaria; pandemic; region; resistance
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        item: #7298 of 7819
          id: cord-349794-mhviub6e
      author: Le, Brian L.
       title: Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19
        date: 2020-10-23
       words: 3814
      flesch: 35
     summary: Using a rank-based pattern matching strategy based on the Kolmogorov-Smirnov Statistic, the signatures were queried against drug profiles from Connectivity Map (CMap). Here, we applied our existing computational drug repositioning pipeline to identify drug profiles with significantly reversed differential gene expression compared to predicted inhibitors (including one tested in Calu-3) were incubated with SARS-CoV-2 infected human embryonic kidney 293T cells overexpressing ACE2 (293T-ACE2) with viral replication determined using an immunofluorescence-based assay.
    keywords: cells; cov-2; covid-19; data; drug; expression; gene; hits; human; sars; signature
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        item: #7299 of 7819
          id: cord-349822-ehidj2ev
      author: Chang, Raymond
       title: Repositioned chloroquine and hydroxychloroquine as antiviral prophylaxis for COVID-19: A protocol for rapid systematic review of randomized controlled trials
        date: 2020-04-23
       words: 2439
      flesch: 41
     summary: In this setting, the existing drugs chloroquine (CQ) and hydroxychloroquine (HCQ) which has suggestive evidence of efficacy against SARS-CoV-2 infection and COVID-19 disease has become prime candidates to be repositioned as therapeutic and preventative agents, and a growing number of clinical trials have been registered to study their preventative potential for at-risk populations using a range of dosing schemes and outcome measures. Notwithstanding a living systematic review protocol has been proposed to assess clinical trials for COVID-19 (Maguire & Guérin, 2020) , and published systematic reviews evaluating CQ and HCQ's role as treatment for COVID-19 (Kapoor & Kapoor, 2020) or assessing clinical trials using CQ and HCQ as treatment while specifically excluding prevention studies (Rana & Dulal, 2020) , there is as yet no protocol for systematically assessing clinical trials that address the preventative 3 .
    keywords: covid-19; license; outcomes; preprint; review; trials
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        item: #7300 of 7819
          id: cord-349836-m9b65l75
      author: Malhotra, C.
       title: Anxiety and perceived risk during COVID-19 outbreak
        date: 2020-07-24
       words: 1641
      flesch: 50
     summary: Contrary to our hypothesis, younger adults experienced higher anxiety, and this associated was not mediated by perceived risk of dying upon getting COVID-19. Future research can seek to better understand why younger adults are experiencing high anxiety.
    keywords: anxiety; covid-19; preprint; risk
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        item: #7301 of 7819
          id: cord-349838-p6vfzbla
      author: Algwaiz, Ghada
       title: Real-world issues and potential solutions in HCT during the COVID-19 pandemic: Perspectives from the WBMT and the CIBMTR's Health Services and International Studies Committee
        date: 2020-07-24
       words: 4064
      flesch: 34
     summary: Exposure (especially to contacts with COVID-19 patients) and symptom history, physical examination, and chest imaging are helpful to evaluate HCT patients. Realizing the challenges as a result of this pandemic affecting the daily practice of the HCT centers, and the recognition of the variability in practice worldwide, the Worldwide Network for Blood &amp; Marrow Transplantation (WBMT) and the Center for International Blood and Marrow Transplant Research&nbsp;(CIBMTR) Health Services and International Studies Committee have jointly produced an expert opinion statement as a general guide to deal with certain aspects of HCT including diagnostics for SARS-CoV-2 in HCT patients, pre-and-post-HCT management, donor issues, medical tourism and facilities management.
    keywords: blood; cell; covid-19; hct; infection; patients; pcr; risk; sars; therapy; transplantation; treatment
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        item: #7302 of 7819
          id: cord-349840-xs2chzmn
      author: Sharma, Varun Kumar
       title: COVID-19 and Anticoagulant based therapeutics: an approach with great promise
        date: 2020-10-07
       words: 639
      flesch: 21
     summary: Figure 1: Anticoagulant based therapeutic could add health benefit to COVID-19 patients via suppressing coagulopathy. J o u r n a l P r e -p r o o f COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up Clinical Characteristics of Coronavirus Disease 2019 in China Thromboembolic risk and anticoagulant therapy in COVID-19 patients: emerging evidence and call for action Coagulation abnormalities and thrombosis in patients with COVID-19 Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Anti-Coagulant and Anti-Platelet Therapy in the COVID-19 Patient: A Best Practices Quality Initiative Across a Large Health System Coagulopathy and Antiphospholipid Antibodies in Patients with Covid Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target
    keywords: covid-19; patients
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        item: #7303 of 7819
          id: cord-349841-eigcqb1b
      author: Boukanjime, Brahim
       title: Dynamics of a stochastic coronavirus (COVID-19) epidemic model with Markovian switching
        date: 2020-10-16
       words: 3026
      flesch: 49
     summary: See [1, 2, 3, 6, 9, 10, 20, 29] and references therein for epidemic models with environmental noise. To demonstrate the effect of telegraph noise on the dynamics of COVID-19 disease, in addition to data of Table 1 , we set the following settings: Then, by direct computation, we obtain R 0 s = 0.6303 < 1.
    keywords: covid-19; disease; epidemic; model; stochastic
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        item: #7304 of 7819
          id: cord-349842-2euxyh5l
      author: Gu, Renjun
       title: The safety and effectiveness of rehabilitation exercises on COVID-19 patients: A protocol for systematic review and meta-analysis
        date: 2020-07-31
       words: 2452
      flesch: 36
     summary: [31] More and more attentions are being attached to the influence of COVID-19 rehabilitation exercises. key: cord-349842-2euxyh5l authors: Gu, Renjun; Xu, Senlei; Li, Ziyun; Gu, Yihuang; Sun, Zhiguang title: The safety and effectiveness of rehabilitation exercises on COVID-19 patients: A protocol for systematic review and meta-analysis date: 2020-07-31 journal: Medicine (Baltimore) DOI: 10.1097/md.0000000000021373 sha: doc_id: 349842 cord_uid: 2euxyh5l BACKGROUND: Corona Virus Disease 2019 (COVID-19) is spreading fast starting late 2019.
    keywords: analysis; covid-19; exercises; patients; rehabilitation; review
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        item: #7305 of 7819
          id: cord-349852-atayq3fi
      author: Volpe, Massimo
       title: COVID-19 and the Forgotten Majority
        date: 2020-08-29
       words: 500
      flesch: 33
     summary: Several dramatic consequences of this sudden situation will face also the enormous burden of other missed medical actions during the COVID-19 crisis. key: cord-349852-atayq3fi authors: Volpe, Massimo; Gallo, Giovanna title: COVID-19 and the Forgotten Majority date: 2020-08-29 journal:
    keywords: covid-19; systems
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        item: #7306 of 7819
          id: cord-349867-e4f3qlae
      author: Nkodo, Jacques-Alexis
       title: Ethical issues in the management of patients with behavioral and psychological symptoms of dementia during COVID-19 containment: examples from institutions in France
        date: 2020-10-06
       words: 878
      flesch: 29
     summary: key: cord-349867-e4f3qlae authors: Nkodo, Jacques-Alexis; Camus, Vincent; Fougère, Bertrand title: Ethical issues in the management of patients with behavioral and psychological symptoms of dementia during COVID-19 containment: examples from institutions in France date: 2020-10-06 journal: Am J Geriatr Psychiatry DOI: 10.1016/j.jagp.2020.10.001 sha: doc_id: 349867 cord_uid: e4f3qlae nan The global pandemic of coronavirus disease 2019 (COVID-19) has prompted many countries to initiate containment measures intended to stem viral transmission. In the unprecedented context of COVID-19 (in which collective interests prevail), containment measures for patients with disruptive BPSD have created organizational difficulties.
    keywords: containment; covid-19; patients
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        item: #7307 of 7819
          id: cord-349868-lb2jcl8m
      author: Patel, Jay
       title: Cardiovascular Considerations of Experimental Hydroxychloroquine Therapy on Patients Diagnosed With COVID-19: A Case Series Review
        date: 2020-07-12
       words: 2355
      flesch: 47
     summary: Hydroxychloroquine (HCQ), a common antimalarial and lupus drug, has been shown to potentially reduce viral carriage and the number of symptomatic days in COVID-19 patients according to an open-label non-randomized French case study of 36 patients [2] . The above two cases add to the ongoing discussion as to whether HCQ therapy in COVID-19 patients is beneficial for all, especially given how it was paired with another arrhythmogenic agent AZM.
    keywords: covid-19; disease; hcq; patients; qtc; risk
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        item: #7308 of 7819
          id: cord-349898-nvi8h77t
      author: Dinh, Ly
       title: COVID‐19 pandemic and information diffusion analysis on Twitter
        date: 2020-10-22
       words: 4779
      flesch: 48
     summary: In light of diverse findings on the extent to which SIR models can explain information diffusion on social networks, we examine whether there are similarities in our simulated SIR model (SIRsim), observed SIR model based on actual COVID-19 cases (SIRemp), and observed information cascades on Twitter about the virus (INFOcas). In the context of social networks, information diffusion is formally defined as a process by which a piece of information is passed down from one node to another node through an edge (Gruhl, Guha, Liben-Nowell, & Tomkins, 2004; Guille, Hacid, Favre, & Zighed, 2013) .
    keywords: cascades; cases; covid-19; diffusion; information; model; sir; tweets; virus
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        item: #7309 of 7819
          id: cord-349899-3hprecor
      author: Cohen, J. A.
       title: Schools are not islands: Balancing COVID-19 risk and educational benefits using structural and temporal countermeasures
        date: 2020-09-10
       words: 6436
      flesch: 47
     summary: This represents about double the risk compared to an elementary-only approach, but gives all K-12 students some time for in-person learning, whereas the elementary-only approach restricts in-person learning to elementary school students, at least initially. Our results support the strategy of returning elementary school students to school either full-time or with an A/B schedule while keeping all other students remote for the first three months of school to best minimize the risk of COVID-19 infection in schools.
    keywords: covid-19; license; person; preprint; reopening; school; students; teachers; transmission
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        item: #7310 of 7819
          id: cord-349902-3ov501xx
      author: Sufian, Abu
       title: A Survey on Deep Transfer Learning and Edge Computing for Mitigating the COVID-19 Pandemic
        date: 2020-06-30
       words: 7860
      flesch: 53
     summary: An incremental improvement Towards an efficient deep learning model for covid-19 patterns detection in x-ray images Covid-19 image data collection Improved deep learning model for differentiating novel coronavirus pneumonia and influenza pneumonia Accurate identification of sars-cov-2 from viral genome sequences using deep learning Rapid ai development cycle for the coronavirus (covid-19) pandemic: Initial results for automated detection & patient monitoring using deep learning ct image analysis Predicting covid-19 incidence through analysis of google trends data in iran: Data mining and deep learning pilot study Composite monte carlo decision making under high uncertainty of novel coronavirus epidemic using hybridized deep learning and fuzzy rule induction Predicting infectious disease using deep learning and big data Genomic diversity of sars-cov-2 in coronavirus disease 2019 patients We shouldnt worry when a virus mutates during disease outbreaks Deep-covid: Predicting covid-19 from chest x-ray images using deep transfer learning Deep learning for screening covid-19 using chest x-ray images A study of the neutrosophic set significance on deep transfer learning models: An experimental case on a limited covid-19 chest x-ray dataset Predicting commercially available antiviral drugs that may act on the novel coronavirus (sars-cov-2) through a drugtarget interaction deep learning model, Computational and structural biotechnology journal Automatic detection of coronavirus disease (covid-19) using x-ray images and deep convolutional neural networks Deep learning for the internet of things with edge computing A survey on optimized implementation of deep learning models on the nvidia jetson platform On-edge multi-task transfer learning: Model and practice with data-driven task allocation Accuracy vs. traffic trade-off of learning iot data patterns at the edge with hypothesis transfer learning Proactive content caching by exploiting transfer learning for mobile edge computing Bandwidth-efficient live video analytics for drones via edge computing Are existing knowledge transfer techniques effective for deep learning with edge devices? 2019 IEEE 39th International Conference on Distributed Computing Systems (ICDCS)
    keywords: computing; covid-19; data; dataset; deep; dtl; edge; images; learning; model; pandemic; ray; transfer
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        item: #7311 of 7819
          id: cord-349909-hmyv1nep
      author: Misa, Nana-Yaa
       title: Racial/ethnic disparities in COVID-19 disease burden & mortality among emergency department patients in a safety net health system
        date: 2020-09-24
       words: 3931
      flesch: 45
     summary: The primary outcome was COVID-19 test positivity rate stratified by race and ethnicity, and the secondary outcome was 30-day in hospital mortality. A strength of our study is that we demonstrate the disparity in COVID-19 test positivity rate to be significant even after controlling for access to care, age, medical co-morbidities, social factors and site of testing.
    keywords: covid-19; disease; health; latinx; mortality; patients; positivity; testing
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        item: #7312 of 7819
          id: cord-349912-em1abdrg
      author: Meng, Xiangming
       title: COVID-19 and anosmia: A review based on up-to-date knowledge
        date: 2020-06-02
       words: 1519
      flesch: 53
     summary: There is increasing evidence that Olfactory dysfunction can present in COVID-19 patients. Multiple cross-sectional studies have demonstrated that the incidence rate of Olfactory dysfunction in COVID-19 patients varies from 33.9–68% with female dominance.
    keywords: cov-2; covid-19; patients; sars
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        item: #7313 of 7819
          id: cord-349945-kur9r5n5
      author: Bataille, Stanislas
       title: Could ferritin help the screening for COVID-19 in hemodialysis patients?
        date: 2020-04-22
       words: 478
      flesch: 43
     summary: Pathophysiological mechanism underlying high ferritin levels is not totally explained at this time, some authors reporting cytokine storm syndrome or macrophage activation syndrome, but in our cohort, ferritin levels were not correlated with c-reactive protein (data not shown) 4,5 . In our hemodialysis center, following the K-DIGO recommendations, ferritin levels are measured each month to detect iron deficiency 3 .
    keywords: ferritin; patients
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        item: #7314 of 7819
          id: cord-349949-jp0hvcg6
      author: Freer, Phoebe E.
       title: The impact of the COVID-19 pandemic on Breast Imaging
        date: 2020-09-22
       words: 5757
      flesch: 39
     summary: In addition to having work and economic worries, some radiologists and staff were redeployed in the early days in hotspots to better serve COVID-19 patient care. Some centers, such as Magee-Breast Cancer Program and Johns Hopkins published multi-disciplinary algorithms of how best to triage breast cancer patients, broken down by sub-types program 21, 22 .
    keywords: breast; cancer; care; coronavirus; covid-19; disease; health; imaging; pandemic; patients; radiology; study
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        item: #7315 of 7819
          id: cord-349954-bozgrzvf
      author: Quintaliani, Giuseppe
       title: Exposure to novel coronavirus in patients on renal replacement therapy during the exponential phase of COVID-19 pandemic: survey of the Italian Society of Nephrology
        date: 2020-07-03
       words: 3457
      flesch: 44
     summary: According to a recent report of the Italian National Institute of Health (Istituto Superiore di Sanità [ISS] ), among the most common comorbidities of COVID-19 patients dying in Italy, chronic kidney disease and dialysis are found in 21% and 2% of deceased patients respectively [10] . Participating Centers and Investigators by Region Iatreion Caserta (I. Raiola) De Paolis) Casa di cura Nuova Villa Claudia A (L. Scabbia) Villa Tiberia Hospital Cepidial srl WHO (2020) Coronavirus disease (COVID-19) pandemic COVID-19 and Italy: what next? Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy COVID-19 World Map COVID-19 integrated surveillance: key national data /en/coron aviru s/sars-cov-2-integ rated -surve illan ce-data COVID-19 infection: the China and Italy perspectives Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis COVID-19 and dialysis: why we should be worried ERACODA: the ERA-EDTA covid-19 database for patients on dialysis or living with a kidney transplant Istituto Superiore di Sanità (2020) Characteristics of COVID-19 patients dying in Italy When a nephrology ward becomes a COVID-19 ward: the Cremona experience COVID-19 outbreak in a large hemodialysis centre in Lombardy A report from the Brescia Renal COVID Task Force on the clinical characteristics and short-term outcome of hemodialysis patients with SARS-CoV-2 infection Brescia Renal CTF (2020) Management of patients on dialysis and with kidney transplant during SARS-COV-2 (COVID-19) pandemic in Working group of the P, Aosta Valley Section of the SIN (2020)
    keywords: centers; covid-19; italy; nephrology; pandemic; patients; rrt; sars; survey
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        item: #7316 of 7819
          id: cord-349973-7441gjda
      author: Ahmed, Y. N.
       title: Predictors of CPAP outcome in hospitalised COVID-19 patients
        date: 2020-06-16
       words: 3381
      flesch: 50
     summary: Discussion: CPAP proved successful in 40% of COVID-19 patients presenting with AHRF. Following this guidance, we created an algorithm for the use of CPAP in COVID-19 patients admitted to our hospital ( Figure 1 ).
    keywords: covid-19; cpap; license; medrxiv; patients; preprint; sfr; success
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        item: #7317 of 7819
          id: cord-349980-x1h5dhn9
      author: Ge, Huiqing
       title: Lung Mechanics of Mechanically Ventilated Patients With COVID-19: Analytics With High-Granularity Ventilator Waveform Data
        date: 2020-08-21
       words: 3550
      flesch: 41
     summary: Recruitment maneuver was not able to improve lung compliance. As compared with supine positioning, prone positioning was associated with 2.31 ml/cmH(2)O (95% CI: 1.75 to 2.86; p < 0.001) increase in lung compliance.
    keywords: compliance; covid-19; lung; patients; positioning; survivors; ventilator
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        item: #7318 of 7819
          id: cord-350001-pd2bnqbp
      author: Liu, L.
       title: Estimating the Changing Infection Rate of COVID-19 Using Bayesian Models of Mobility
        date: 2020-08-07
       words: 5520
      flesch: 48
     summary: [10] develop a Bayesian semimechanistic (rather than compartmental) model linking Google mobility data and a latent timevarying factor to a time-varying reproductive number R t , which is combined with a latent IFR and time-to-death distribution to model observed deaths. On the other hand, compartmental models [e.g., 1, 6, 7] assume a flexible, causal story for the spread of a disease and can also incorporate mobility data as a covariate for predicting the time-varying infection rate of a disease.
    keywords: compartmental; covid-19; data; death; infection; mobility; model; parameters; rate; time
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        item: #7319 of 7819
          id: cord-350006-c4be9eii
      author: Martina, Stefano
       title: The Perception of COVID-19 among Italian Dentists: An Orthodontic Point of View
        date: 2020-06-18
       words: 3957
      flesch: 48
     summary: key: cord-350006-c4be9eii authors: Martina, Stefano; Amato, Alessandra; Rongo, Roberto; Caggiano, Mario; Amato, Massimo title: The Perception of COVID-19 among Italian Dentists: An Orthodontic Point of View date: 2020-06-18 journal: Int J Environ Res Public Health DOI: 10.3390/ijerph17124384 sha: doc_id: 350006 cord_uid: c4be9eii COVID-19 has severely impacted dentists, who are at a great risk of infection. An online questionnaire, including the Patient Health Questionnaire-4 (PHQ-4), was sent to Italian dentists during the final days of the lockdown with items about anxiety, fear, distress, perceived risk for operators, and concerns about orthodontic patients caused by working during the COVID-19 outbreak.
    keywords: covid-19; dentists; distress; fear; patients; risk
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        item: #7320 of 7819
          id: cord-350015-mg5wiihj
      author: Chen, Yiyin
       title: Aging in COVID-19: Vulnerability, immunity and intervention
        date: 2020-10-31
       words: 7507
      flesch: 33
     summary: It remains to be seen whether this provides any protection against COVID-19 Grifoni et al., 2020; Mateus et al., 2020; Sette and Crotty, 2020) . Studies aimed at defining factors that impact the quality and titer of antibody, including SARS-CoV-2 neutralization reveal that older age, male sex, and hospitalization with severe COVID-19 are all factors that contribute to greater antiviral antibody responses against SARS-CoV-2 . Cell-mediated immune response: Clinical observations have revealed significant lymphopenia and increased neutrophil counts in severe COVID-19 disease and, therefore, lymphopenia and high neutrophil-lymphocyte ratio (NLR) are considered as useful predictors for COVID-19 death whereas high lymphocyte counts predict better clinical outcomes (Chen et al., 2020c; Lagunas-Rangel and Chavez-Valencia, 2020; Qin et al., 2020; Wang et al., 2020a; Zhou et al., 2020a) .
    keywords: adults; age; cell; china; coronavirus; cov-2; covid-19; disease; et al; immune; infection; patients; responses; sars; vaccine
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        item: #7321 of 7819
          id: cord-350016-yxf7ykva
      author: Qin, Le
       title: A predictive model and scoring system combining clinical and CT characteristics for the diagnosis of COVID-19
        date: 2020-07-01
       words: 3925
      flesch: 44
     summary: Inclusion criteria for patients suspected of COVID-19 were set according to the sixth edition of the Diagnosis and Treatment Program of COVID-19 proposed by The National Health Commission of the People's Republic of China: (1) epidemiological history: history of travel to Wuhan or history of residence in Wuhan or other areas with continuous transmission of local cases within 14 days before the onset of the disease, history of contact with COVID-19 patients within 14 days before the onset of the disease, and clustering or epidemiological association with COVID-19, and (2) clinical features: fever and/or disorder of the respiratory system, imaging manifestations of COVID-19 pneumonia, normal or reduced leukocyte count, or reduced lymphocyte count. From January 19 to February 6, 2020, 88 confirmed COVID-19 patients presenting with pneumonia and 80 non-COVID-19 patients suffering from pneumonia of other origins were retrospectively enrolled.
    keywords: 2019; clinical; covid-19; patients; pcr; pneumonia
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        item: #7322 of 7819
          id: cord-350029-1y5ex4d5
      author: McDade, Thomas W.
       title: Beyond serosurveys: Human biology and the measurement of SARS‐Cov‐2 antibodies
        date: 2020-08-09
       words: 2690
      flesch: 36
     summary: In this commentary, we describe antibody testing and how human biologists can use it to inform our understanding of the pandemic, and to address questions of longstanding interest regarding the causes and consequences of human biological variation. Based on these dynamics, antibody testing can be applied clinically to diagnose a current or very recent infection, and epidemiologically as a surveillance tool.
    keywords: antibodies; antibody; cov-2; covid-19; infection; sars; testing
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        item: #7323 of 7819
          id: cord-350041-b1vmnwv2
      author: Cena, Hellas
       title: Coronavirus Disease (COVID-19–SARS-CoV-2) and Nutrition: Is Infection in Italy Suggesting a Connection?
        date: 2020-05-07
       words: 3024
      flesch: 23
     summary: Furthermore, while waiting for clinical trials to shed light on the clinical efficacy and beneficial effects of antibodies and anti-inflammatory cytokines, we highlight nutritionally derived products that may inhibit the inflammatory cytokine secretion caused by COVID-19 infection. Data accumulating from COVID-19 patients indicate that these patients might have a cytokine storm syndrome, with markedly higher levels of IFN-γ, CCL-2, CCL-3, TNF, and the aforementioned IL-6 (30-32).
    keywords: covid-19; data; disease; immune; infection; influenza; obesity; patients
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        item: #7324 of 7819
          id: cord-350053-bgtl85mq
      author: Terzi, Francesca
       title: Intramural Hematoma as Unexpected Complication of COVID-19 Infection
        date: 2020-06-04
       words: 956
      flesch: 36
     summary: Acute intramural hematoma of the aorta: a mystery in evolution Evaluation of aortic wall inflammation in acute aortic intramural hematoma using FDG-PET/CT in relation to prognostic aorta-related outcome Detection of inflammation in patients with acute aortic syndrome: comparison of FDG-PET/CT imaging and serological markers of inflammation ESC Guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. However, only the evolving understanding of the multiple mechanisms in which the virus, or the immune response to it, attacks human cells will lead to a better comprehension and treatment of the protean manifestations of COVID-19 disease.
    keywords: aorta; aortic; covid-19; patient
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        item: #7325 of 7819
          id: cord-350059-c25md0vm
      author: Delgado, Diego
       title: Personal Safety during the COVID-19 Pandemic: Realities and Perspectives of Healthcare Workers in Latin America †
        date: 2020-04-18
       words: 2548
      flesch: 46
     summary: Healthcare workers in Latin America had limited access to essential PPE and support from healthcare authorities during the COVID-19 pandemic. Our objective was to evaluate the reality and perceptions about personal safety among healthcare workers in Latin America.
    keywords: access; covid-19; healthcare; workers
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        item: #7326 of 7819
          id: cord-350062-6xsh2pis
      author: Juul, Sophie
       title: Interventions for treatment of COVID-19: A living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)
        date: 2020-09-17
       words: 9056
      flesch: 47
     summary: We planned to conduct aggregate data meta-analyses, trial sequential analyses, network meta-analysis, and individual patient data meta-analyses. We used trial sequential analysis to control for random errors [23]
    keywords: analysis; care; covid-19; events; evidence; meta; risk; standard; trial
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        item: #7327 of 7819
          id: cord-350065-frg7gvf5
      author: Parolari, Alessandro
       title: Safety for all: coronavirus disease 2019 pandemic and cardiac surgery: a roadmap to ‘phase’ 2
        date: 2020-05-11
       words: 2444
      flesch: 41
     summary: Although some areas have used the 'hub and spoke' approach whereby hospitals delivering cardiac surgery are not routinely treating COVID-19 patients, the focus and the challenge during phase 2 are the reconversion of the cardiac surgical departments where resources had previously been redeployed for the treatment of infected patients, the most common approach adopted in Italy during phase 1. Given that these institutions will continue to care for COVID-19 patients, we recommend that clearly separated pathways in COVID-19dedicated and COVID-19-free areas are developed within the hospital.
    keywords: areas; cardiac; care; covid-19; patients; risk
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        item: #7328 of 7819
          id: cord-350066-xwf7u4n5
      author: Zhang, Baozhen
       title: Acupuncture for breathlessness in COVID-19: A protocol for systematic review and meta-analysis
        date: 2020-07-02
       words: 2708
      flesch: 38
     summary: Chinese herbs combined with Western medicine for severe acute respiratory syndrome (SARS) Traditional Chinese medicine for COVID-19 treatment Is traditional Chinese medicine useful in the treatment of COVID-19? [12] In total, 303 ongoing clinical trials concerning the assessment of the therapeutic safety and efficacy for COVID-19 patients have been launched in China by March 1, 2020, 50 of which focus on TCM, including 14 clinical trials aimed at evaluating the efficacy of TCM combined with Western medicine.
    keywords: acupuncture; analysis; covid-19; meta; patients; review; study; treatment
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        item: #7329 of 7819
          id: cord-350082-n39wakfp
      author: Yi, Zhan-Miao
       title: Mapping Evidence of Pharmacy Services for COVID-19 in China
        date: 2020-10-02
       words: 5636
      flesch: 28
     summary: Yang et al., 2020a; Yang et al., 2020b; Zhou H. et al., 2020) published most of the articles (Figure 3) . For contents of included 91 articles, 39 articles (42.86%) were related to routine pharmacy services under the restrict limit of COVID-19 outbreak Cao et al., 2020; Che et al., 2020; Chen et al., 2020a; Chen L. P. et al., 2020; Du et al., 2020; Duan et al., 2020; Guo et al., 2020; Han et al., 2020; Hu Z. Q. et al., 2020; Lin and Zhang, 2020; Li Q. C. et al., 2020; Liu and Yan, 2020; Peng et al., 2020; Shao et al., 2020; Song B. et al., 2020; Song Z. W. et al., 2020; Wang R. R. et al., 2020; Xiong et al., 2020a; Xiong et al., 2020b; Yang et al., 2020a; Yang et al., 2020b; Yan J. L. et al., 2020; Yang L. et al., 2020;
    keywords: articles; care; control; coronavirus; covid-19; disease; et al; pharmaceutical; pharmacists; pharmacy; prevention; services
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        item: #7330 of 7819
          id: cord-350110-tybh207e
      author: Poggiali, Erika
       title: Can Lung US Help Critical Care Clinicians in the Early Diagnosis of Novel Coronavirus (COVID-19) Pneumonia?
        date: 2020-03-13
       words: 299
      flesch: 31
     summary: Radiology CT Imaging Features of 2019 Novel Coronavirus (2019-nCoV) Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases Lung ultrasound for daily monitoring of ARDS patients on extracorporeal membrane oxygenation: preliminary experience Point-of-care ultrasonography in patients admitted with respiratory symptoms: a single-blind, randomised controlled trial Lung US Surface Wave Elastography in Interstitial Lung Disease Staging The authors would like to thank all the emergency doctors and nurses of their hospital for the help and energy to face such a difficult public health crisis. Organizing pneumonia was confirmed in four patients as well as detected with lung US.
    keywords: lung; patients
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        item: #7331 of 7819
          id: cord-350130-c4u0gxp5
      author: Wu, Yi-Chi
       title: The outbreak of COVID-19: An overview
        date: 2020-02-12
       words: 3352
      flesch: 53
     summary: In 2003, a new coronavirus, the etiology of a mysterious pneumonia, also originated from southeast China, especially Guangdong province, and was named SARS coronavirus that fulfilled the Koch's postulate. Antiviral drugs: lopinavir/ritonavir and ribavirin had been tried to treat SARS disease with apparent favorable clinical response.
    keywords: 2019; coronavirus; covid-19; infection; ncov; novel; patients; sars
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        item: #7332 of 7819
          id: cord-350131-rsrlri8m
      author: Amer, Mohamed A.
       title: Early recovery patterns of olfactory disorders in COVID-19 patients; a clinical cohort study
        date: 2020-09-14
       words: 2168
      flesch: 38
     summary: On the other hand, some centers adopt using short course of oral steroid in patients with a persistent loss of smell related to COVID-19 and in those patients with persistent loss of sense of smell following covid-19 after at least two weeks since diagnosis, they believe that this protocol seems to give better outcomes than observation (22) To our knowledge, this is the 1 st Egyptian article discussing otorhinolaryngological manifestations of COVID-19 patients with detailed analysis of olfactory dysfunction and their pattern of recovery during COVID-19 pandemic, however, the present study Clinical Characteristics of Coronavirus Disease 2019 in China WHO coronavirus disease (COVID-19) dashboard, WHO, viewed 03 Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore Early recovery following new onset anosmia during the COVID-19 pandemic -an observational cohort study Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study The diagnosis of a conductive olfactory loss Pivotal Role of Receptor-Interacting Protein Kinase 1 and Mixed Lineage Kinase Domain-Like in Neuronal Cell Death Induced by the Human Neuroinvasive Coronavirus OC43 Prevalence and Duration of Acute Loss of Smell or Taste in COVID-19 Patients Development and validity of the DyNaChron questionnaire for chronic nasal dysfunction Possible link between anosmia and COVID-19: sniffing out the truth Association of chemosensory dysfunction and Covid-19 in patients presenting with influenza-like symptoms Incomplete and late recovery of sudden olfactory dysfunction in COVID-19 Acute-onset smell and taste disorders in the context of COVID-19: a pilot multicentre polymerase chain reaction based case-control study Early recovery following new onset anosmia during the COVID-19 pandemic an observational cohort study Severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) infection is likely to be androgen mediated Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis COVID-19 infection and glucocorticoids: update from the Italian Society of Endocrinology Expert Opinion on steroid replacement in adrenal insufficiency Intranasal corticosteroids in allergic rhinitis in COVID-19 infected patients: an ARIA-EAACI statement Anosmia and loss of smell in the era of covid-19 The mean age of patients was 34.26±11.91 years 56 females(56.3%) and 40 males with evident female predominance, this goes in accordance with Kosugi et al (13) who studied 183 olfactory patients of COVID-19 with mean age of 36 years and female predominance 53.1% of their patients , similarly, in a multicentric study of COVID-19 patients performed by Lechien et al.
    keywords: covid-19; olfactory; patients; recovery; study
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        item: #7333 of 7819
          id: cord-350134-gl3qtoug
      author: Brun, Gilles
       title: COVID-19—White matter and globus pallidum lesions: Demyelination or small-vessel vasculitis?
        date: 2020-05-22
       words: 1014
      flesch: 41
     summary: Besides demyelination, the associated punctiform lesions might be consistent with ischemic lesions because of small-vessel vasculitis. key: cord-350134-gl3qtoug authors: Brun, Gilles; Hak, Jean-François; Coze, Stéphanie; Kaphan, Elsa; Carvelli, Julien; Girard, Nadine; Stellmann, Jan-Patrick title: COVID-19—White matter and globus pallidum lesions: Demyelination or small-vessel vasculitis? date: 2020-05-22 journal:
    keywords: cov-2; covid-19; lesions; sars
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        item: #7334 of 7819
          id: cord-350172-w3yoxhsg
      author: Mertens, Pascal
       title: Development and Potential Usefulness of the COVID-19 Ag Respi-Strip Diagnostic Assay in a Pandemic Context
        date: 2020-05-08
       words: 7577
      flesch: 41
     summary: The post-implementation analysis of the proposed algorithm using samples collected in the LHUB-ULB between the 31st of March and the 7th of April 2020 from patients in four hospitals from Brussels showed 33.3% (325/975) total positive COVID-19 test results, of which 39.7% (129/325) were detected by the COVID-19 Ag Respi-Strip. In the absence of a vaccine and specific antiviral treatment, the containment of the pandemic relies mainly on the rapid identification and isolation of COVID-19 patients (2) .
    keywords: ag respi; assay; clinical; covid-19; covid-19 ag; diagnostic; patients; pcr; respi; results; samples; sars; strip; study; test
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        item: #7335 of 7819
          id: cord-350177-j9wyrfse
      author: Stewart, John A.
       title: ILCOR’s revised Covid-19 defibrillation recommendation requires a new approach to training
        date: 2020-11-07
       words: 1319
      flesch: 29
     summary: Focused defibrillation training promises to decrease confusion and delay in Covid-19 resuscitation efforts. Most resuscitation interventions assume a supine patient, but Covid-19 patients are frequently positioned prone.
    keywords: covid-19; defibrillation; resuscitation
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        item: #7336 of 7819
          id: cord-350179-ltk5hfc4
      author: Paganini, Matteo
       title: Translating COVID-19 Pandemic Surge Theory to Practice in the Emergency Department: How to Expand Structure
        date: 2020-03-27
       words: 4427
      flesch: 44
     summary: This study reviewed the available surge science literature specifically to guide an emergency department’s surge structural response using a translational science approach to answer the question: How does the concept of sudden onset mass casualty incident surge capability apply to the process to expand COVID-19 pandemic surge structure response? How does the concept of sudden onset mass casualty incident (MCI) surge capability apply to the process to expand COVID-19 pandemic surge structure response?
    keywords: care; covid-19; health; mci; patients; response; space; staff; structure; surge; team
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        item: #7337 of 7819
          id: cord-350182-s10nong7
      author: Milionis, Charalampos
       title: A brief analysis and hypotheses about the risk of COVID-19 for people with type 1 and type 2 diabetes mellitus
        date: 2020-07-20
       words: 2734
      flesch: 35
     summary: As of June 29, 2020, the number of COVID-19 infections globally has exceeded 10 million cases in 188 countries/regions causing more than 500,000 deaths [9] . Clinical and basic evidence Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Commentary.
    keywords: covid-19; diabetes; immune; mellitus; patients; sars; type
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        item: #7338 of 7819
          id: cord-350185-xastx0qi
      author: Whembolua, Guy-Lucien
       title: Public trust in the time of the Coronavirus Disease 2019 (COVID-19): the case of the DR Congo
        date: 2020-04-09
       words: 1309
      flesch: 39
     summary: More specifically, using the PEN-3 cultural model, we assessed the socio-cultural factors affecting public trust in the government and its agencies (i.e., the main regulator of public health in the country) prior to the announcement of the first reported COVID-19 case on March 10th 2020, one day before the World Health Organization declared the disease a pandemic [1] . In the near future, Congolese health leaders may have to build on the DRC past experience with the Ebola Virus Disease where local leaders and savoir-faire were used not only to contain the disease, but to also launch multi-media prevention campaign that addresses all the different inaccurate information currently spread in the population.
    keywords: covid-19; disease; drc; health
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        item: #7339 of 7819
          id: cord-350200-1w5u3w8i
      author: Hendren, Elizabeth M.
       title: An Interprofessional Approach in Caring for a Patient on Maintenance Hemodialysis with COVID-19 in Toronto, Canada: An Educational Case Report
        date: 2020-09-08
       words: 3333
      flesch: 44
     summary: Finally, dialysis patients were informed of each change in the screening protocol with a printed letter provided in the HD unit, along with updated signs posted at the entrance of the dialysis unit. Our early experiences may provide insight into the importance of maintaining an interprofessional approach in caring for HD patients with COVID-19.
    keywords: care; covid-19; dialysis; hospital; infection; patient; screening
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        item: #7340 of 7819
          id: cord-350207-izkzl39p
      author: Prost, Stephanie Grace
       title: Prisons and COVID-19: A Desperate Call for Gerontological Expertise in Correctional Health Care
        date: 2020-07-24
       words: 2328
      flesch: 34
     summary: Critical gerontological knowledge and skills needed in prison health care include awareness regarding the unusual clinical presentations of COVID-19 among older adults, deconditioning among older adults due to immobility, challenges in prognostication, and advance care planning with older adults. We describe the critical gerontological knowledge and skills needed by prison health care professionals to meet the challenge of providing appropriate care for older adults in prisons during the COVID-19 pandemic, and call on our colleagues in gerontology to establish and maintain partnerships with correctional health care professionals to help address the growing geriatric health crisis in prisons.
    keywords: adults; care; covid-19; health; prisons; professionals
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        item: #7341 of 7819
          id: cord-350232-zml4o93t
      author: Peck, Richard W
       title: A Real‐World Evidence Framework for Optimising Dosing in All Patients with COVID‐19
        date: 2020-05-23
       words: 1932
      flesch: 37
     summary: Pharmacologic treatments for coronavirus Disease 2019 (COVID-19) Challenges in drug deve;opment posed by the COVID-19 pandemic: An opportunity for clinical pharmacology Drug dosing recommendations for all patients: A roadmap for change Optimizing hydroxychloroquine dosing for patients with COVID-19: An integrative modelling approach for effective drug repurposing Groups at high risk of severe illness CYP-mediated therapeutic protein-drug interactions Timing of antiviral treatment initiation is critical to reduce SARS-CoV-2 viral load The gendered dimensions of COVID-19 NIH to launch public-private partnership to speed COVID-19 vaccine and treatment options A model-and real world data-based framework for continuous updating of dosing recommendations and labelling of treatments for COVID-19 patients (hsCRP: high sensitivity C-reactive protein, Rx: treatment, PKPD: pharmacokinetic/pharmacodynamics, VK: viral kinetic. Several drugs are being repurposed into clinical trials in COVID-19 patients, ranging from drugs already well established in other diseases, such as chloroquine/hydroxychloroquine, lopinavir+ ritonavir, azithromycin and tocilizumab/sarilumab, to those such as remdesivir still in development for their initial indication (1) .
    keywords: covid-19; data; disease; drug; patients
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        item: #7342 of 7819
          id: cord-350236-7fit8q1s
      author: Wan, Bin
       title: On-site analysis of COVID-19 on the surfaces in wards
        date: 2020-08-18
       words: 1569
      flesch: 47
     summary: To our knowledge, we present the first on-site analysis of COVID-19 surface contamination in wards. Therefore, surface contamination in wards should be monitored for disease control and hygiene purposes.
    keywords: contamination; covid-19; detection; samples; surface
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        item: #7343 of 7819
          id: cord-350239-jwwazskv
      author: Begley, J. L.
       title: Assessing the risk of nosocomial infection posed by COVID‐19 tracheal intubation: the first intubateCOVID results
        date: 2020-07-22
       words: 456
      flesch: 36
     summary: Specifically: • If the virus was contracted during tracheal intubation, we would expect to see a peak of onset at around 5 days with a significant reduction in new cases after 12 days, consistent with the known incubation period [2] ; however, no such distribution was seen (their Fig. 4 ), • There was no increase in risk associated with the absence of personal protective equipment (PPE) (their Table 2 ), • There was no increase in risk associated with intubating a patient's trachea with confirmed COVID-19 vs. a patient with merely suspected disease (their Table 4 ), and • There was no association between the number of tracheal intubations performed and the primary outcome (their Supplementary Fig. However, many readers would be more interested in knowing to what extent performing tracheal intubation directly exposes them to the risk of contracting COVID-19.
    keywords: intubation; tracheal
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        item: #7344 of 7819
          id: cord-350255-tthttyl3
      author: Poirier, Canelle
       title: The role of environmental factors on transmission rates of the COVID-19 outbreak: an initial assessment in two spatial scales
        date: 2020-10-12
       words: 4294
      flesch: 42
     summary: www.nature.com/scientificreports/ once we excluded R proxy values above 3 (third step of filtering), mobility was found to be associated with R proxy (p value = 0.01). Visualization of the relationship between COVID-19 transmission as captured by R proxy and temperature and humidity.
    keywords: covid-19; data; humidity; proxy; relationship; temperature; time; transmission
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        item: #7345 of 7819
          id: cord-350261-7lkcdisr
      author: Asirvatham, Edwin Sam
       title: Who is dying from COVID-19 and when? An Analysis of fatalities in Tamil Nadu, India
        date: 2020-10-03
       words: 3430
      flesch: 40
     summary: Though there are several studies from other countries that explained the characteristics of COVID-19 deaths, there is a dearth of peer-reviewed and published literature from India. The patients who were admitted in private hospitals had a median of 4 days of symptoms as compared to public hospital patients with 3 days of symptoms (P<0.005).
    keywords: admission; covid-19; death; hospital
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        item: #7346 of 7819
          id: cord-350281-vmz7gnhm
      author: Meleveedu, Kapil S
       title: Tocilizumab for severe COVID-19 related illness – A community academic medical center experience
        date: 2020-09-02
       words: 4430
      flesch: 44
     summary: The inappropriately elevated levels of inflammatory cytokines in COVID-19 patients is similar to cytokine release syndrome (CRS) observed in cell therapy patients.  COVID-19 patients can develop a hyperinflammatory state akin to cytokine release syndrome (CRS) as seen in cell therapy patients with elevated IL-6 levels along with other proinflammatory cytokines.
    keywords: anti; covid-19; crs; data; il-6; levels; patients; therapy; treatment
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        item: #7347 of 7819
          id: cord-350321-jy4i403g
      author: Ku, Benson S.
       title: Associations Between Primary Care Provider Shortage Areas and County-Level COVID-19 Infection and Mortality Rates in the USA
        date: 2020-08-21
       words: 757
      flesch: 39
     summary: COVID-19 infection and death rates were higher in whole county primary care HPSAs compared with non-whole county primary care HPSAs (overall median: 30.9 vs 18.0 per 10,000 residents and 1.1 vs 0.7 per 10,000 residents, respectively). There were 170 (13.2%) whole county primary care HPSAs and 1121 (86.8%) areas that were not whole county primary care HPSAs.
    keywords: care; covid-19; primary
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        item: #7348 of 7819
          id: cord-350325-vu8v9epr
      author: Malih, Narges
       title: Unexpected Presentation of COVID-19 in a 38-Year-Old Male Patient: A Case Report
        date: 2020-07-29
       words: 1695
      flesch: 56
     summary: Data A special gratitude we give to Vice-Chancellor for Health Affairs of Shahid Beheshti University of Medical Sciences, whose contribution in stimulating suggestions and encouragement, helped us to join to primary health care clinic of Shahid Beheshti University of Medical Sciences, which is specialized for COVID-19 epidemic and made us have unique experiences on COVID-19 disease. The cutaneous manifestations of COVID-19 cases in Recalcati
    keywords: case; covid-19; patients; rash; symptoms
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        item: #7349 of 7819
          id: cord-350338-lcsa06gm
      author: Wang, Kun
       title: Clinical and laboratory predictors of in-hospital mortality in patients with COVID-19: a cohort study in Wuhan, China
        date: 2020-05-03
       words: 2475
      flesch: 45
     summary: The MuLBSTA Score Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding From gene to proteinexperimental and clinical studies of ACE2 in blood pressure control and arterial hypertension Preparing for the next influenza pandemic An interferon-γ-related cytokine storm in SARS patients Corticosteroid Treatment Ameliorates Acute Lung Injury Induced by 2009 Swine Origin Influenza A (H1N1) Virus in Mice The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration Understanding the T cell immune response in SARS coronavirus infection Biochemical Aspects of Coronavirus Replication and Virus-Host Interaction Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Specific ACE2 Expression in Cholangiocytes Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical features of patients infected with 2019 novel coronavirus in Wuhan Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster Machine learning for the prediction of volume responsiveness in patients with oliguric acute kidney injury in critical care Boosted tree model reforms multimodal magnetic resonance imaging infarct prediction in acute stroke Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis (TRIPOD) Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach Innate immune responses in the ageing lung Clinical Features Predicting Mortality Risk in Patients With Viral Pneumonia:
    keywords: clinical; cohort; covid-19; hospital; model; patients; study
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        item: #7350 of 7819
          id: cord-350375-07l9hqsr
      author: Escher, Allan R
       title: An Ounce of Prevention: Coronavirus (COVID-19) and Mass Gatherings
        date: 2020-03-20
       words: 1003
      flesch: 49
     summary: Public Health for Mass gatherings: Key Considerations Mass gatherings medicine: public health issues arising from mass gathering religious and sporting events Are high-performing health systems resilient against the COVID-19 epidemic? Deferment or cancellation of such mass gatherings may exert an extraordinary economic loss to the host nation.
    keywords: covid-19; gatherings; mass
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        item: #7351 of 7819
          id: cord-350377-vq9eblr0
      author: Sukumar, Vivek
       title: Colorectal Services in Covid-19 Times: Minimally Invasive Surgery and Enhanced Recovery, the Need of the Hour
        date: 2020-10-14
       words: 2172
      flesch: 44
     summary: The challenges we face today as healthcare professionals are unparalleled, but we have successfully demonstrated the feasibility of cancer surgery during these difficult times by following strict protocols in testing, safety of personnel, and aggressive perioperative and post-operative care. Exclusion criteria included patients with incomplete medical records, primarily admitted with another department for whom surgical cover was provided by the division of colorectal surgery and day care procedures.
    keywords: covid-19; days; patients; post; stay; surgery
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        item: #7352 of 7819
          id: cord-350379-6l55soxu
      author: Lee, Jenny J.
       title: Scientific globalism during a global crisis: research collaboration and open access publications on COVID-19
        date: 2020-07-24
       words: 6228
      flesch: 33
     summary: It may be for this reason that less-resourced countries are more likely to be involved in international research collaboration than independent research (Pouris & Ho, 2016; Iglic, Doreian, Kronegger, & Ferligoj, 2017) . Toward a model of collaboration propensity The geopolitics of academic science Unseen workers in the academic factory: perceptions of neo-racism among international postdocs in the US and UK A bibliometric analysis of COVID-19 research activity: A call for increased output Open access archiving: the fast track to building research capacity in developing countries Humanity wins: our fight to unlock 32,544 COVID-19 articles for the world New approach to the visualization of international scientific collaboration Bibliometric analysis of severe acute respiratory syndrome-related research in the beginning stage Evolution and convergence of the patterns of international scientific collaboration Coronavirus Drives the U.S. and China Deeper Into Global Power Struggle Bibliometric analysis of global scientific research on coronavirus (COVID-19)
    keywords: access; articles; china; collaboration; countries; country; covid-19; covid-192020; publications; research; science; study
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        item: #7353 of 7819
          id: cord-350383-a7wa571o
      author: Sudeep, HV
       title: Molecular docking analysis of Withaferin A from Withania somnifera with the Glucose regulated protein 78 (GRP78) receptor and the SARS-CoV-2 main protease
        date: 2020-04-30
       words: 1675
      flesch: 48
     summary: In this study we have used the molecular docking tool to understand the interactions of natural products with plausible targets of SARS-CoV-2 infection such as host cell receptor GRP78 and COVID-19 M pro . The ability of protein active sites to bind to drug-like molecules with extreme affinity is a major phase of target identification in drug discovery [20] .
    keywords: compounds; covid-19; grp78; protein; withaferin
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        item: #7354 of 7819
          id: cord-350390-ukoi8jyg
      author: Demkina, A. E.
       title: Risk factors for outcomes of COVID-19 patients: an observational study of 795 572 patients in Russia
        date: 2020-11-04
       words: 4095
      flesch: 45
     summary: key: cord-350390-ukoi8jyg authors: Demkina, A. E.; Morozov, S.; Vladzymyrskyy, A. V.; Kljashtorny, V. G.; Guseva, O. I.; Pugachev, P. S.; Artemova, O. R.; Reshetnikov, R. V.; Gombolevskiy, V. A.; Ryabinina, M. N. title: Risk factors for outcomes of COVID-19 patients: an observational study of 795 572 patients in Russia date: 2020-11-04 journal: nan DOI: 10.1101/2020.11.02.20224253 sha: doc_id: 350390 cord_uid: ukoi8jyg Background Several factors that could affect survival and clinical outcomes of COVID-19 patients require larger studies and closer attention. Patients All subjects, regardless of age, admitted to 4,251 Russian hospitals indexed in the Federal Register of COVID-19 patients between March 26, 2020, and June 3, 2020.
    keywords: covid-19; medrxiv; patients; preprint; risk; study
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        item: #7355 of 7819
          id: cord-350406-o90k48vy
      author: Mannheim, Jonathan
       title: Characteristics of Hospitalized Pediatric Coronavirus Disease 2019 Cases in Chicago, Illinois, March–April 2020
        date: 2020-06-01
       words: 2112
      flesch: 40
     summary: Symptomology of children with COVID-19 throughout the United States has been described [1] ; however, to date no report on pediatric patients in a large urban center with data on underlying comorbidities and coinfection for the most severe cases has been published. The median age of pediatric patients with COVID-19 during this time was 11 years (interquartile range, 7-16 years)
    keywords: children; covid-19; disease; patients; years
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        item: #7356 of 7819
          id: cord-350429-v36lrg3p
      author: Iyengar, Karthikeyan
       title: Learning opportunities from COVID-19 and future effects on health care system
        date: 2020-06-20
       words: 1532
      flesch: 43
     summary: We have undertaken a comprehensive review of the current literature to analyse the consequences of COVID-19 on health care system. Government initiatives -COVID 19 has exposed health care system of many countries including India.
    keywords: care; covid-19; health; india; pandemic
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        item: #7357 of 7819
          id: cord-350437-dq1il88y
      author: Reale, Maria Lucia
       title: SARS-CoV-2 Infection in Cancer Patients: A Picture of an Italian Onco-Covid Unit
        date: 2020-08-19
       words: 4183
      flesch: 42
     summary: This retrospective study aims to collect epidemiological, clinical, laboratory, and therapeutic data from SARS-CoV-2 positive cancer patients hospitalized at the Onco-Covid unit in San Luigi Gonzaga Hospital, Italy, one of the few oncological wards for cancer patients with SARS-Cov-2 infection, in order to provide a deeper insight into the clinical evolution of infection in cancer patients, particularly in lung cancer patients. Cancer patients are one of the potentially most vulnerable cohorts of people, but data about their management are still few.
    keywords: cancer; covid-19; data; days; diagnosis; infection; patients; sars; treatment
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        item: #7358 of 7819
          id: cord-350450-43v36b2s
      author: Jakhar, Deepak
       title: Dermoscopy Practice during COVID-19 Pandemic: Recommendations by SIG Dermoscopy (IADVL Academy)
        date: 2020-05-10
       words: 840
      flesch: 40
     summary: Wherever possible, for COVID-19 suspected patients, standardized protocol of wearing personalized protective equipments (PPE) and examination in negative pressure rooms should be followed. A first perspective Dermatology practices as vectors for COVID-19 transmission: Acall for immediate cessation of non-emergent dermatology visits Prevention of possible cross-infection among patients by dermoscopy: Abrief review of the literature and our suggestion Initiation of a new infection control system for the COVID-19 outbreak Preventing cross-infection during polarized dermoscopy using hand held dermatoscope Virologic safety of polyvinyl chloride film in dermoscopic analysis of mucosal areas Innovative modification of the USB dermatoscope for mucoscopy Using a car phone holder for performing oculoscopy with auniversal serial bus dermatoscope
    keywords: covid-19; dermatoscope; dermoscopy
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        item: #7359 of 7819
          id: cord-350456-lter7hy2
      author: Lewis, Shantel
       title: Diagnostic radiographers’ experience of COVID-19, gauteng south africa
        date: 2020-09-18
       words: 2820
      flesch: 46
     summary: The study information letter outlined the purpose of the study as well as provided the opportunity for radiographers to express their experiences of COVID-19 without The demographic data of participants is presented in Radiographers' responses to the question How has your experience been during COVID-19? were read and reread to obtain a general sense of the data. Diagnostic radiographers in Gauteng providing chest CT, chest radiograph and MRI services are frontline workers experiencing these unprecedented times.
    keywords: africa; covid-19; health; radiographers; south; study; work
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        item: #7360 of 7819
          id: cord-350460-80eu9b9c
      author: Che Azemin, Mohd Zulfaezal
       title: COVID-19 Deep Learning Prediction Model Using Publicly Available Radiologist-Adjudicated Chest X-Ray Images as Training Data: Preliminary Findings
        date: 2020-08-18
       words: 2207
      flesch: 38
     summary: Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review Clinical characteristics of imported cases of Coronavirus Disease 2019 (COVID-19) in Jiangsu province: a multicenter descriptive study Clinical and CT features in pediatric patients with COVID-19 infection: different points from adults ChestX-ray8: hospital-scale chest X-ray database and benchmarks on weakly-supervised classification and localization of common thorax diseases Scan: structure correcting adversarial network for organ segmentation in chest X-rays Deep learning with lung segmentation and bone shadow exclusion techniques for chest X-ray analysis of lung cancer Comparison of deep learning approaches for multi-label chest X-ray classification Chest X-ray generation and data augmentation for cardiovascular abnormality classification Deep learning for grading cardiomegaly severity in chest x-rays: an investigation ImageNet classification with deep convolutional neural networks Chest radiograph interpretation with deep learning models: assessment with radiologist-adjudicated reference standards and populationadjusted evaluation Interpretive error in radiology COVID-19 image data collection Deep residual learning for image recognition Rapid AI development cycle for the coronavirus (COVID-19) pandemic: initial results for automated detection & patient monitoring using deep learning CT image analysis COVID-CT-dataset: a CT scan dataset about COVID-19 COVID-19 screening on chest X-ray images using deep learning based anomaly detection Can AI help in screening viral and COVID-19 pneumonia? Grad-CAM: visual explanations from deep networks via gradient-based localization Informatics in radiology: efficiency metrics for imaging device productivity Operational efficiency Deep learning for chest radiograph diagnosis: a retrospective comparison of the CheX-NeXt algorithm to practicing radiologists Application of deep learning technique to manage COVID-19 in routine clinical practice using CT images: results of 10 convolutional neural networks The authors declare that there is no conflict of interest regarding the publication of this article. We used a deep learning model based on the ResNet-101 convolutional neural network architecture, which was pretrained to recognize objects from a million of images and then retrained to detect abnormality in chest X-ray images.
    keywords: chest; covid-19; data; images; learning; set
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        item: #7361 of 7819
          id: cord-350466-z5yvfo22
      author: Jena, Anuraag
       title: Fecal calprotectin levels in COVID-19: Lessons from a systematic review on its use in inflammatory bowel disease during the pandemic
        date: 2020-10-19
       words: 775
      flesch: 43
     summary: 1 Use of fecal calprotectin, especially home-based testing, has been suggested as a tool for remote monitoring during the COVID pandemic. Recent reports, including one published in the journal, about elevations of fecal calprotectin in COVID-19 raise concerns about this strategy of home based monitoring using fecal calprotectin.
    keywords: calprotectin; covid-19
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        item: #7362 of 7819
          id: cord-350468-32qin4ak
      author: Song, Cong-Ying
       title: Immune dysfunction following COVID-19, especially in severe patients
        date: 2020-09-28
       words: 2965
      flesch: 47
     summary: Parameters including CD4 + T cell count, NLR, and D-dimer, CT score, and CPIS had quite great value for predicting disease severity, which could be considered in early warning of severe patients. CT score and CPIS were higher in severe patients and these two clinical scores were positively related to disease severity.
    keywords: cell; clinical; covid-19; disease; patients; score
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        item: #7363 of 7819
          id: cord-350473-f47i7y5h
      author: Sen-Crowe, Brendon
       title: COVID-19 laboratory testing issues and capacities as we transition to surveillance testing and contact tracing
        date: 2020-05-27
       words: 1103
      flesch: 47
     summary: Johns Hopkins -Center for Health Security The value of urine biochemical parameters in the prediction of the severity of coronavirus disease 2020;/j/cclm.ahead-of-print HHS funds development of COVID-19 diagnostic tests. The sensitivity of PCR tests have been estimated at 71%, resulting in ~30% of infected patients having a negative finding.
    keywords: covid-19; sensitivity; testing; tests
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        item: #7364 of 7819
          id: cord-350492-1s6wtj25
      author: Ruscitti, Piero
       title: Severe COVID-19, Another Piece in the Puzzle of the Hyperferritinemic Syndrome. An Immunomodulatory Perspective to Alleviate the Storm
        date: 2020-05-28
       words: 3732
      flesch: 17
     summary: Interestingly, severe COVID-19 is characterized by fever, hyperferritinemia, and a hyper-inflammatory process with a massive release of pro-inflammatory cytokines, which may be responsible for the high rate of mortality. The latter is the result of overwhelming systemic inflammation with a massive release of pro-inflammatory cytokines, quickly progressing to multiple organ dysfunction syndrome and eventually to death (23) .
    keywords: activation; covid-19; cytokine; disease; ferritin; hlh; hyperferritinemia; patients; syndrome
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        item: #7365 of 7819
          id: cord-350498-jwweg06f
      author: Abebe, Ayele
       title: Awareness of Health Professionals on COVID-19 and Factors Affecting It Before and During Index Case in North Shoa Zone, Ethiopia, 2020
        date: 2020-08-24
       words: 3723
      flesch: 53
     summary: African countries with the highest estimated numbers of COVID-19 cases were South Africa, Egypt, Morocco, Algeria, and Cameroon. Based on Africa Centers for Disease Control and Prevention (Africa CDC), 43 African countries have reported COVID-19 cases so far.
    keywords: awareness; cases; covid-19; disease; health; level; professionals; study
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        item: #7366 of 7819
          id: cord-350519-3h5ipcwn
      author: Paul, L. A.
       title: Characteristics associated with household transmission of SARS-CoV-2 in Ontario, Canada
        date: 2020-10-26
       words: 5195
      flesch: 47
     summary: In this retrospective study of 26,152 confirmed cases of COVID-19 residing in 21,226 private households, we found that longer testing delays and male sex were associated with greater odds of household secondary transmission, while being a healthcare worker or linked to a known outbreak was associated with lower odds of household transmission. Existing individual-level observational studies of household transmission typically included household contacts identified through contact tracing.
    keywords: cases; characteristics; covid-19; household; index; odds; preprint; studies; transmission
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        item: #7367 of 7819
          id: cord-350521-jfd5gd2p
      author: Bong, Choon-Looi
       title: The COVID-19 Pandemic: Effects on Low- and Middle-Income Countries
        date: 2020-04-20
       words: 3717
      flesch: 56
     summary: This will further reduce resources available for health care, not just in managing COVID-19 patients, but also for those with many other major medical conditions. As the global COVID-19 situation unfolds and countries are forced to take unprecedented drastic measure, including border closures, travel bans, and social distancing, we will likely witness the devastating and profound impact of this pandemic not only in health care but also on the world economy.
    keywords: care; countries; covid-19; disease; health; lmics; pandemic; patients; world
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        item: #7368 of 7819
          id: cord-350529-yqtu059x
      author: Evans, Samantha
       title: Implementation of a clinical pathway for the surgical treatment of colorectal cancer during the COVID‐19 pandemic
        date: 2020-07-12
       words: 1930
      flesch: 45
     summary: St Mark's Hospital in London, UK addressed these challenges at an early stage, as their campus was identified as one of the capital's main referral centres for COVID-19 patients. The operating rooms and wards of St Mark's Hospital at the London North West University Hospitals NHS Trust were not operational due to a surge of COVID-19 patients from the 25 th March to the 9 th April 2020.
    keywords: cancer; covid-19; pandemic; patients; surgery
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        item: #7369 of 7819
          id: cord-350540-s6is9ndm
      author: Pinto, Rogério M.
       title: COVID-19 Pandemic Disrupts HIV Continuum of Care and Prevention: Implications for Research and Practice Concerning Community-Based Organizations and Frontline Providers
        date: 2020-04-28
       words: 2029
      flesch: 38
     summary: The New York Times Perspectives of Linkage to Care Among People Diagnosed With HIV HIV testing, care referral and linkage to care intervals affect time to engagement in care for newly diagnosed HIV-infected adolescents in fifteen adolescent medicine clinics in the United States Challenges and Successes in Linking HIV-Infected Women to Care in the United States Barriers and facilitators of linkage to HIV primary care in New York City Barriers to HIV Care and Treatment Among Participants in a Public Health HIV Care Relinkage Program Why Physicians Don't Ask: Interpersonal and Intrapersonal Barriers to HIV Testing-Making a Case for a Patient-Initiated Campaign A client-centered relational framework on barriers to the integration of HIV and substance use services: a systematic review Factors that influence linkages to HIV Continuum of Care Services: Implications for multi-Level interventions Unpredictable Work Timing in Retail Jobs: Implications for Employee Work-Life Conflict Limited effectiveness of antiviral treatment for hepatitis C in an urban HIV clinic The Values and Value of Patient-Centered Care Beyond patient-centred care: A conceptual framework of co-production mechanisms with vulnerable groups in health and social service settings Crossing the Quality Chasm: A New Health System for the 21st Century What 'patient-centered' should mean: Confessions of an extremist Retention in HIV care among participants in the patient-centered hiv care model: a collaboration between community-based pharmacists and primary medical providers Is the quality of the patient-provider relationship associated with better adherence and health outcomes for patients with HIV? Co-production in the treatment of substance use disorder and its relationship to clinic's service output patterns Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Furthermore, evidence suggests that frontline providers who more frequently link clients to HIV services tend to do so as part of face-to-face client meetings, at which the provider might ask the client, while still in their presence, to contact the referral, or the provider might make the contact and hand the client written information [12] .
    keywords: care; clients; health; hiv; providers; services
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        item: #7370 of 7819
          id: cord-350578-wyz5jyjh
      author: Bai, Li
       title: Chinese experts’ consensus on the Internet of Things-aided diagnosis and treatment of coronavirus disease 2019 (COVID-19)
        date: 2020-12-31
       words: 5459
      flesch: 38
     summary: To avoid misdiagnosis, suspected patients should be isolated and monitored for 14 days. nCapp intelligent assisted treatment and management for patients suspected of COVID-19 nCapp automatically generates prompt diagnosis according to the national guidelines, and patients who meet the criteria are suggested to be reported or transferred to the designated hospitals.
    keywords: cloud; coronavirus; covid-19; data; diagnosis; ncapp; online; patients; pneumonia; technology; treatment
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        item: #7371 of 7819
          id: cord-350589-h6hotlqk
      author: Cieszanowski, Andrzej
       title: Management of patients with COVID-19 in radiology departments, and indications regarding imaging studies – recommendations of the Polish Medical Society of Radiology
        date: 2020-04-29
       words: 3429
      flesch: 52
     summary: Imaging studies in COVID-19 patients are best performed in less-attended areas of RDs, to avoid unnecessary exposure of personnel and other patients [8] . • • Where numbers of scanners in an RD are sufficient, machines for COVID-19 patients and for others are designated as separate [7] .
    keywords: chest; covid-19; examination; imaging; infection; patients; sars
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        item: #7372 of 7819
          id: cord-350594-0zxq4lxc
      author: Patel, Ishan
       title: Life-Threatening Psoas Hematoma due to Retroperitoneal Hemorrhage in a COVID-19 Patient on Enoxaparin Treated With Arterial Embolization: A Case Report
        date: 2020-06-25
       words: 1830
      flesch: 37
     summary: Anticoagulation therapy, while indicated in COVID-19 patients, has its own challenges and guidelines describing dosages and indications in this disease are lacking. To the best of our knowledge, we report first case of retroperitoneal hemorrhage due to lumbar artery bleeding in a patient of COVID-19 being treated with enoxaparin, highlighting importance of judicious use of anticoagulation in COVID-19 patients as well as the need of prompt radiological investigation and treatment of bleeding.
    keywords: anticoagulation; bleeding; covid-19; embolization; patient
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        item: #7373 of 7819
          id: cord-350614-4umq61rf
      author: Freeman, Phyllis
       title: Richard Horton. The COVID-19 Catastrophe: What’s gone wrong and how to stop it happening again: Polity Press, Cambridge, UK, 2020. pp 133, Paperback $14.95USD, ISBN-13:978-1-5095-4645-9 and 13:978-1-5095-4645-9 (pb)
        date: 2020-09-17
       words: 1300
      flesch: 52
     summary: The Chinese and Italians noticed by March 2020 that not only was COVID-19 transmitted person to person, it seemed to be spreading through asymptomatic carriers-who no one had known could be vectors [2] . Horton catalogues lessons for better preparation for a next pandemic (pp. 85-86; 103)-en route to a more philosophic discussion and listing of questions about how humans view the role of societies in handling uncertainty, risk, wealth, knowledge, deprivation, and differences among us in characteristics and values-and how western societies need urgently to find a way to balance liberty and scrutiny (think about 'surveillance') in managing their people.
    keywords: covid-19; health; horton; societies
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        item: #7374 of 7819
          id: cord-350618-rtilfnzi
      author: Lambelet, Valentine
       title: Sars‐CoV‐2 in the context of past coronaviruses epidemics: Consideration for prenatal care
        date: 2020-05-26
       words: 7296
      flesch: 45
     summary: Regarding fetal growth surveillance, RCOG recommends an antenatal ultrasound fourteen days after acute illness resolution for hospitalized patients, while ACOG suggests a 3 rd trimester ultrasound for COVID-19 pregnant women infected in 2 nd and 3 rd trimester. For COVID‐19 infection, only 9 cases of maternal death have been reported as of April 22, 2020 and pregnant women seem to develop the same clinical presentation as the general population.
    keywords: article; cases; clinical; copyright; coronavirus; cov-2; covid-19; fetal; infection; outcomes; patients; pregnancy; rights; sars; women
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        item: #7375 of 7819
          id: cord-350622-8tgxdbyi
      author: Palit, Partha
       title: Phytopharmaceuticals mediated Furin and TMPRSS2 receptor blocking: can it be a potential therapeutic option for Covid-19?
        date: 2020-10-28
       words: 5090
      flesch: 24
     summary: The receptor-binding domain (RBD) of S-protein after cleavage mediating processing, followed by activation, is responsible for binding with ACE2; while the interaction of S-protein with host cell ACE2 receptor helps the virus to invade the host cell (Li et al., 2005) . It has been found that Furin and TMPRSS2 could play a significant role for efficient attachment of cleaved S-protein with host cell ACE2 receptor via activation, priming, and fusion, followed by endosomal internalization to establish pathogenicity through replication, growth, and spread of the infecting virus to another organ's cell.
    keywords: ace2; anti; cell; covid-19; drug; et al; host; infection; receptor; sars; virus
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        item: #7376 of 7819
          id: cord-350636-ufwfitue
      author: Shumilov, Evgenii
       title: Comparison of Chest Ultrasound and Standard X-Ray Imaging in COVID-19 Patients
        date: 2020-09-02
       words: 2371
      flesch: 42
     summary: We aimed to investigate patterns of ChUS in COVID-19 patients and compare the findings with results from chest X-ray (CRX). ChUS was especially useful to detect interstitial syndrome compared to CXR in COVID-19 patients (17/18 vs. 11/18; p<0.02).
    keywords: chus; covid-19; cxr; lung; patients
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        item: #7377 of 7819
          id: cord-350639-iguadmw1
      author: Padlina, G
       title: Secondary Cerebrovascular Prevention in Light of the COVID-19 Pandemic
        date: 2020-08-05
       words: 2547
      flesch: 38
     summary: Our way of providing cerebrovascular secondary prevention at the neurovascular laboratory at the Inselspital, University Hospital of Bern/Switzerland, has been established and adapted over years. Normally, we offer cerebrovascular secondary prevention for patients in both in-and outpatient settings.
    keywords: covid-19; disease; pandemic; patients; prevention; risk; stroke
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        item: #7378 of 7819
          id: cord-350648-y0ufxwhq
      author: Bahn, Geon Ho
       title: Coronavirus Disease 2019, School Closures, and Children’s Mental Health
        date: 2020-04-01
       words: 3951
      flesch: 46
     summary: The author briefly reviewed the existing literature on the mental health aspects of disasters and presents the issues related to school closures due to pandemics, from medical and socioeconomic perspectives and in terms of children’s mental health. The results of this review suggest that research on children’s mental health in relation to the adoption of school closures as a pandemic mitigation strategy is urgently needed.
    keywords: children; closures; covid-19; health; influenza; outbreak; pandemic; parents; school
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        item: #7379 of 7819
          id: cord-350655-04dq9b4r
      author: Ulas, T.
       title: Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients
        date: 2020-07-08
       words: 7925
      flesch: 44
     summary: Interestingly, expression of 214 CYTOR was significantly increased in severe COVID-19 patient group G1 (p<0.001) and correlated with 215 both PIK3CB (r= 0.53, p<0.001) and VIM (r= 0.55, p<0.001) (Fig. 2F ). Similarly to SARS-CoV and 83 MERS-CoV infections, hyperinflammation due to excessive release of proinflammatory cytokines is often 84 observed in severe COVID-19 patients as increased serum IL-6 levels correlate with respiratory failure and 85 adverse clinical outcomes (9, 30, 31) .
    keywords: author; copyright holder; covid-19; fig; funder; july; license; medrxiv preprint; patients; perpetuity; preprint; version
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        item: #7380 of 7819
          id: cord-350660-12ienbdx
      author: Huang, Wei
       title: Lymphocyte Subset Counts in COVID‐19 Patients: A Meta‐Analysis
        date: 2020-06-15
       words: 2270
      flesch: 37
     summary: Several reports coming out of China have revealed that patients with the most severe cases of COVID-19 have abnormalities in many laboratory parameters, such as elevated procalcitonin, lactate dehydrogenase, Ddimer, C-reactive protein, neutrophil counts and pro-inflammatory cytokines, such as interleukin- 6. 3 Lymphopenia and thrombocytopenia are also associated with severe COVID-19 disease. This meta-analysis shows that absolute counts of major lymphocyte subsets are significantly and substantially decreased in severe COVID-19 disease.
    keywords: cell; counts; covid-19; disease; lymphocyte; patients
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        item: #7381 of 7819
          id: cord-350679-69lv4wbz
      author: Shinde, Rajesh S.
       title: To Do or Not to Do?—A Review of Cancer Surgery Triage Guidelines in COVID-19 Pandemic
        date: 2020-05-11
       words: 3480
      flesch: 38
     summary: Deferring cancer surgeries for this long period may have a direct impact on the long-term outcomes of cancer patients. Due to overall rising cancer incidence and specific concerns, a cohort of cancer patients forms a distinct subset of the population in whom a correct and timely treatment has a huge impact on the outcome.
    keywords: cancer; cov-2; covid-19; disease; pandemic; patients; sars; surgeries; surgery; treatment
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        item: #7382 of 7819
          id: cord-350700-cmwy5we8
      author: Ahmed, M.
       title: Optimizing breast cancer surgery during the COVID-19 pandemic
        date: 2020-09-18
       words: 1511
      flesch: 35
     summary: Ethical approval This article does not contain any studies with human participants or animals performed by the author. editorial board of The B. Recommendations for triage, prioritization and treatment of breast cancer patients during the COVID-19 pandemic Recommendations for prioritization, treatment, and triage of breast cancer patients during the COVID-19 pandemic. key: cord-350700-cmwy5we8 authors: Ahmed, M. title: Optimizing breast cancer surgery during the COVID-19 pandemic date: 2020-09-18 journal:
    keywords: breast; cancer; pandemic; surgery
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        item: #7383 of 7819
          id: cord-350714-zfprrxt4
      author: Yao, Ye
       title: Association of particulate matter pollution and case fatality rate of COVID-19 in 49 Chinese cities
        date: 2020-06-20
       words: 1674
      flesch: 40
     summary: We found positive associations between PM pollution and COVID-19 CFR in cities both inside and outside Hubei Province. PM pollution distribution and its association with COVID-19 CFR suggests that exposure to such may affect COVID-19 prognosis.
    keywords: covid-19; pollution
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        item: #7384 of 7819
          id: cord-350767-6kc4hyzo
      author: Beh, Darius L L
       title: The Pandemic Academy: Reflections of Infectious Diseases Fellows During COVID-19
        date: 2020-06-25
       words: 2467
      flesch: 49
     summary: As we mark 3 months of our fellowship in the COVID-19 era, we reflect on our experiences and the unique impact of this pandemic on ID fellows. Strange as it may be for ID fellows, our specific role during a pandemic of this scale is not well-defined.
    keywords: covid-19; fellows; pandemic
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        item: #7385 of 7819
          id: cord-350784-v8n44lwa
      author: Walker, J. L.
       title: UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records
        date: 2020-08-26
       words: 5243
      flesch: 41
     summary: On 5 March 2019, 24·4% of the UK population were at higher risk than others of the same age due to underlying health conditions, including 8·3% of school-aged children, 19·6% of working-aged adults, and 66·2% of individuals aged ≥70 years. 3, 4 Older individuals are at higher risk of severe COVID-19 than younger, independent of underlying health conditions.
    keywords: conditions; covid-19; disease; health; individuals; population; prevalence; risk; years
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        item: #7386 of 7819
          id: cord-350817-tmszrtju
      author: Hoepel, Willianne
       title: Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses
        date: 2020-07-13
       words: 5645
      flesch: 39
     summary: Moreover, the hyper-inflammatory response induced by anti-Spike IgG can be specifically counteracted in vitro by use of the active component of fostamatinib, an FDA- and EMA-approved therapeutic small molecule inhibitor of Syk. Combined, these data hint towards the involvement of anti-Spike IgG in severe cases of COVID-19.
    keywords: anti; antibodies; cells; covid-19; cytokine; figure; human; igg; macrophages; patients; polyic; production; sars; serum; spike
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        item: #7387 of 7819
          id: cord-350821-0qfoc553
      author: Jahromi, Reza
       title: Synergistic effects of anionic surfactants on coronavirus (SARS-CoV-2) virucidal efficiency of sanitizing fluids to fight COVID-19
        date: 2020-06-01
       words: 1944
      flesch: 41
     summary: Evaporation time increased by 17-63% when surfactant agents were added to the liquid. The surrounding environment was isolated to eliminate possible air convection, and the room temperature was maintained at ~27 ºC. The exact amount of evaporation time was recorded for each sprayed liquid.
    keywords: coronavirus; evaporation; liquid; solution; time; virucidal
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        item: #7388 of 7819
          id: cord-350822-m3t7l9zw
      author: Mo, Yuanyuan
       title: Work stress among Chinese nurses to support Wuhan in fighting against COVID‐19 epidemic
        date: 2020-05-20
       words: 3622
      flesch: 51
     summary: The procedures of this study were reviewed and approved by the Stress overload: A new approach to the assessment of stress National support Wuhan medical staff zero infection Global challenges in health and health care for nurses and midwives everywhere Job stress and burnout in hospital employees: Comparisons of different medical professions Analysis of nurse anxiety and its influencing factors Conscientiousness, openness to experience and extraversion as predictors of nursing work performance: A facet-level analysis Anxiety symptoms among Chinese nurses and the associated factors: A cross sectional study Psychosocial job factors and biological cardiovascular risk factors in Mexican workers COVID-19: Multiple regression analysis showed that only children, working hours per week and anxiety were the main factors affecting nurse stress (p = .000, .048, .000, respectively).
    keywords: anxiety; covid-19; health; load; nurses; score; stress; work
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        item: #7389 of 7819
          id: cord-350823-6pmvftgk
      author: Chirove, F.
       title: A model assessing potential benefits of isolation and mass testing on COVID-19: the case of Nigeria
        date: 2020-09-03
       words: 5519
      flesch: 46
     summary: We observe that increasing mass testing is associated with increase in cumulative self isolation cases and as well as cumulative admissions of symptomatic cases especially from I s into monitored isolation centres. https://doi.org/10.1101/2020.09.01.20186288 doi: medRxiv preprint social distancing and shielding in the reduction of COVID-19 cases in Africa using data from Mauritius, Nigeria and Niger.
    keywords: cases; covid-19; license; mass; medrxiv; model; preprint; testing
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        item: #7390 of 7819
          id: cord-350842-4m82l5t8
      author: Xing, Jun
       title: Study of the mental health status of medical personnel dealing with new coronavirus pneumonia
        date: 2020-05-19
       words: 3223
      flesch: 44
     summary: In subsequent research in this project, a longitudinal study should be conducted that uses a wider sample and measures the mental health status of medical personnel from multiple dimensions, which can help better identify the mutual influence between demographic data and mental health status. key: cord-350842-4m82l5t8 authors: Xing, Jun; Sun, Ning; Xu, Jun; Geng, Shuling; Li, Yuqian title: Study of the mental health status of medical personnel dealing with new coronavirus pneumonia date: 2020-05-19 journal: PLoS One DOI: 10.1371/journal.pone.0233145 sha: doc_id: 350842 cord_uid: 4m82l5t8
    keywords: coronavirus; covid-19; health; medical; personnel; status
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        item: #7391 of 7819
          id: cord-350859-0khu9mz3
      author: Grotto, Rejane Maria Tommasini
       title: Increasing molecular diagnostic capacity and COVID-19 incidence in Brazil
        date: 2020-08-18
       words: 1673
      flesch: 35
     summary: With that in mind, we studied the increase in COVID-19 molecular diagnostic capacity of public health laboratories in different regions in Brazil. The primacy of the growth of cases over laboratory capacity is reinforced by the increase in hospital admissions and deaths (as reported in official data (https://covid.saude.gov.br/) and recent studies [7, 8] ).
    keywords: brazil; covid-19; health; increase; laboratories
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        item: #7392 of 7819
          id: cord-350904-wyg8ikph
      author: Gubernatorova, E.O.
       title: IL-6: relevance for immunopathology of SARS-CoV-2
        date: 2020-05-20
       words: 8333
      flesch: 28
     summary: COVID-19 patients also show significant changes in coagulative status (i.e. low platelet count, increased D-dimer, fibrinogen levels) and dysfunction of microvessels in pulmonary circulation [82, 83] , thus, thrombosis of the pulmonary capillaries is believed to contribute to rapidly developing hypoxia. In line with this, recent studies have reported that COVID-19 patients have increased Angiotensin II compared to healthy individuals [103] .
    keywords: ace2; acute; angiotensin; cells; coronavirus; cov-2; covid-19; cytokine; disease; expression; il-6; immune; infection; lung; patients; receptor; sars; syndrome; virus
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        item: #7393 of 7819
          id: cord-350907-lazslqn0
      author: Isik, Ahmet Turan
       title: Covid-19 Infection in Older Adults: A Geriatrician’s Perspective
        date: 2020-07-06
       words: 1534
      flesch: 41
     summary: 1, 2 Regarding the severe course of the disease in the elderly, I would like to draw attention to some issues related to the diagnosis of Covid-19 infections in older patients. 14 Considering that this period is 2.5 days in Covid-19 patients who do not need intensive care and are younger, the fact that dyspnea occurs approximately 6.5 days after the first symptom 14 is also striking in terms of the importance of atypical presentations.
    keywords: covid-19; disease; fever; patients
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        item: #7394 of 7819
          id: cord-350919-by4zwniq
      author: Chowdhuri, Indrajit
       title: Significant decrease of lightning activities during COVID-19 lockdown period over Kolkata megacity in India
        date: 2020-07-28
       words: 2698
      flesch: 53
     summary: A higher amount of pre-monsoon lightning flash is reported over the Kolkata megacity area than the monsoon period (Chaudhuri and Middey, 2013) . The main objectives of this study are therefore to analyze the trend of ambient air pollutants (PM 10 , NO 2 , SO 2 , O 3 and aerosol) during the lockdown and pre-lockdown periods.
    keywords: air; lightning; lockdown; period; pre
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        item: #7395 of 7819
          id: cord-350935-p6euuop3
      author: Doğan, Tunca
       title: CROssBAR: Comprehensive Resource of Biomedical Relations with Deep Learning Applications and Knowledge Graph Representations
        date: 2020-09-15
       words: 7070
      flesch: 40
     summary: In CROssBAR knowledge graphs (CROssBAR-KG), biological components/terms (i.e., drugs/compounds, genes/proteins, bio-processes/pathways, phenotypes/diseases) are represented as nodes, and their known or predicted pairwise relationships are annotated as edges (a protein and its coding gene is treated as one merged term/entry/node). Currently, CROssBAR knowledge graphs do not include PubChem data due to both elevated computational demand (the sizes of PubChem collections are large) and high redundancy (a large portion of bioactivity data points in PubChem and ChEMBL databases are shared).
    keywords: biomedical; compound; covid-19; crossbar; data; database; disease; genes; graph; knowledge; nodes; proteins; terms
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        item: #7396 of 7819
          id: cord-350941-hlx60qyr
      author: Pang, Peng
       title: 51.22 USING TELEPHONIC FOLLOW-UP TO ASSESS ADOLESCENT FUNCTIONING DURING THE COVID-19 SHUTDOWN IN HENAN, CHINA
        date: 2020-10-31
       words: 1780
      flesch: 45
     summary: We examined visit completion rates of patients due for a study visit on April 1, 2020 performed in the remote care visit window (April 1, 2020 to May 31, 2020) by visit type (month 6, month 24, other visit) and institution type (community vs academic) to in-person visits from the coinciding preceding enrollment period (April 1, 2019 to May 31, 2019). Conclusions: Overall visit completion rates comparing the pre-COVID-19 enrollment period in 2019 to the same period in 2020 did not show significant changes in visit completion rates.
    keywords: covid-19; visit
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        item: #7397 of 7819
          id: cord-350946-o8eohq9h
      author: van Buuren, Asia
       title: “COVID-19 as the equalizer”: Evolving discourses of COVID-19 and implications for medical education
        date: 2020-09-23
       words: 869
      flesch: 42
     summary: In this work, we will examine: 1) the discourse(s) that have emerged during the COVID-19 pandemic that highlight population-level inequities, and 2) the implications these discourses have for medical education, the learning environment, and the care patients receive from medical trainees. In medical education, this methodology has been successful in identifying practices, linked to language use, that can advantage or disadvantage learners, faculty, and patients.
    keywords: covid-19; education; pandemic
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        item: #7398 of 7819
          id: cord-350949-ystkjdwk
      author: Gao, Yi-jie
       title: Clinical features and outcomes of pregnant women with COVID-19: a systematic review and meta-analysis
        date: 2020-08-03
       words: 4524
      flesch: 48
     summary: The incidences of fever, cough and positive CT findings in pregnant women with COVID-19 are less than those in the normal population with COVID-19, but the rate of preterm labor is higher among pregnant with COVID-19 than among normal pregnant women. The rate of preterm labor in normal pregnant women worldwide who are healthy and not infected with any virus is lower than that in pregnant women with COVID-19.
    keywords: analysis; clinical; cov-2; covid-19; patients; sars; women
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        item: #7399 of 7819
          id: cord-350990-tywbe4o2
      author: Checchi, Vittorio
       title: COVID‐19 dentistry‐related aspects: a literature overview
        date: 2020-07-05
       words: 3725
      flesch: 36
     summary: Therefore, dental procedures can be considered as one of the most probable causes of Sars-CoV-2 infection because such procedures require close proximity to the patient's mouth, possess a risk of contact with saliva, blood and other biological fluids and involve the use of instrumentation that creates large aerosols 4, 19, 20 . In dental procedures, the mask should be considered as disposable and the mean surgical period does not exceed 2 hours; therefore, it is suggested to use a mask with the highest filtration efficacy without a valve, or a valved mask covered by a surgical mask.
    keywords: air; coronavirus; cov-2; covid-19; filtration; infection; mask; patients; protection; sars
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        item: #7400 of 7819
          id: cord-350992-l6l24pco
      author: Roldan, Eugenia Quiros
       title: The possible mechanisms of action of 4-aminoquinolines (chloroquine/hydroxychloroquine) against Sars-Cov-2 infection (COVID-19): A role for iron homeostasis?
        date: 2020-05-13
       words: 8052
      flesch: 35
     summary: As stated above, CQ/HCQ not only interfere with cellular iron inducing its starvation in alveolar macrophages [122, 123] , then possibly resulting in a switch to M2 antiinflammatory state, but also inhibit IL-6, IL-1 and TNF- release, possibly reducing local HAMP release by macrophages. Then CQ/HCQ could also inhibit iron release from endosomes into the cytosol.
    keywords: action; activation; cells; chloroquine; cov-2; covid-19; drugs; effect; hcq; hydroxychloroquine; infection; iron; macrophages; patients; release; sars; treatment
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        item: #7401 of 7819
          id: cord-351004-h6fde7vm
      author: Gudipati, Smitha
       title: Descriptive Analysis of Patients Living With HIV Affected by COVID-19
        date: 2020-07-13
       words: 2474
      flesch: 50
     summary: Our case series, the current published literature on HIV and SARS-CoV-2, and the published data from HFH on COVID-19 patients without known HIV supports the theory that there is not an excess morbidity and mortality among PLWH affected by COVID-19 compared with the general public. 4 In the United States, Detroit, Michigan, had become a hotspot of COVID-19 infected patients with the number of confirmed cases reaching 47,182 as of May 8, 2020, with 4555 deaths in Michigan (fourth most deaths in the United States).
    keywords: covid-19; hiv; infection; patients; plwh; sars
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        item: #7402 of 7819
          id: cord-351017-yntcwq9t
      author: Li, Xuelian
       title: COVID-19, insurer board utility, and capital regulation
        date: 2020-06-18
       words: 2243
      flesch: 47
     summary: key: cord-351017-yntcwq9t authors: Li, Xuelian; Lin, Panpan; Lin, Jyh-Horng title: COVID-19, insurer board utility, and capital regulation date: 2020-06-18 journal: The result thereby contributes to insurance stability since insurer capital serves directly for policyholder protection (Insurance Europe, 2014).
    keywords: board; covid-19; insurance; insurer; outbreak
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        item: #7403 of 7819
          id: cord-351022-8y43jhmu
      author: Schwartz, Carmela
       title: A dynamic response to exposures of healthcare workers to newly diagnosed COVID-19 patients or hospital personnel, in order to minimize cross transmission and need for suspension from work during the outbreak
        date: 2020-09-01
       words: 2902
      flesch: 50
     summary: Furthermore, immediate epidemiological investigation and, if needed, early suspension from work of exposed HCWs is needed in order to limit the spread of infection to and between HCWs and patients (7) (8) . Immediate epidemiological investigations of exposed HCWs were initiated, in order to break the chain of cross-transmission between HCWs as well as avoiding transmission from HCWs to patients, thus keeping maximal work force available.
    keywords: covid-19; hcws; isolation; work
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        item: #7404 of 7819
          id: cord-351031-e8suoeim
      author: Liang En Ian, Wee
       title: Containing COVID-19 outside the isolation ward: the impact of an infection control bundle on environmental contamination and transmission in a cohorted general ward
        date: 2020-06-26
       words: 4139
      flesch: 38
     summary: The details of COVID-19 patients detected in the RSW, as well as the numbers of patient and staff closecontacts, are provided in Table 1 Uniquely, our study provided the opportunity to investigate the extent of environmental contamination in COVID-19 patients housed in a general ward setting, early on at the point of initial admission; although this was modified by the effects of our infection control bundle.
    keywords: cases; close; contacts; covid-19; general; patients; transmission
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        item: #7405 of 7819
          id: cord-351038-k2m6woow
      author: Arun Krishnan, R.
       title: COVID-19: Current Trends in Invitro Diagnostics
        date: 2020-06-27
       words: 2901
      flesch: 44
     summary: In vitro diagnostic assays for COVID-19: recent advances and emerging trends Laboratory testing for 2019 novel coronavirus (2019-Ncov) in suspected human cases Real-time RT-PCR in COVID-19 detection: issues affecting the results Viral load kinetics of SARS-CoV-2 infection in first two patients in Korea Loop-mediated isothermal amplification of DNA Comparison of realtime PCR, reverse transcriptase real-time PCR, loop-mediated isothermal amplification, and the FDA conventional microbiological method for the detection of Salmonella spp. In case of antibody detection assay, both IgG and IgM antibodies against the COVID-19 are the target analytes where IgM appears in blood within a week of time and IgG expression will take more than 10 days.
    keywords: coronavirus; cov-2; covid-19; detection; pcr; protein; sars; test
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        item: #7406 of 7819
          id: cord-351040-j3ltpaa0
      author: Naser Moghadasi, Abdorreza
       title: Encephalopathy associated with COVID-19 in a patient with multiple sclerosis
        date: 2020-10-28
       words: 1398
      flesch: 48
     summary: Herein, a 34-year-old patient with MS who experienced the decreased level of consciousness and encephalopathy following COVID-19 involvement has been reported. Herein, we reported a patient with MS who experienced the decreased level of consciousness and encephalopathy following COVID-19 involvement.
    keywords: covid-19; csf; involvement; patient
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        item: #7407 of 7819
          id: cord-351056-5j8uh1yx
      author: Liu, Gaoli
       title: Clinical significance of nutritional risk screening for older adult patients with COVID-19
        date: 2020-05-13
       words: 3382
      flesch: 51
     summary: key: cord-351056-5j8uh1yx authors: Liu, Gaoli; Zhang, Shaowen; Mao, Zhangfan; Wang, Weixing; Hu, Haifeng title: Clinical significance of nutritional risk screening for older adult patients with COVID-19 date: 2020-05-13 journal: We retrospectively analyzed the data of patients with COVID-19 older than 65 years who were treated in our hospital from January 28, 2020 to March 5, 2020, and explored the relationship between nutritional risk and clinical outcomes.
    keywords: covid-19; mna; nri; nrs; patients; risk
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        item: #7408 of 7819
          id: cord-351057-xrv3k1fo
      author: Alenazi, Thamer H.
       title: Prevalence and predictors of anxiety among healthcare workers in Saudi Arabia during the COVID-19 pandemic
        date: 2020-10-05
       words: 3971
      flesch: 44
     summary: Participants reporting high anxiety levels were more likely to be unmarried (OR = 1.32, 95% CI: 1.14–1.52); nurses (OR = 1.54, 95% 1.24–1.91); workers in radiology (OR = 1.52, 95% CI: 1.01–2.28); or respiratory therapists (OR = 2.28, 95% CI: 1.14–4.54). Social factors associated with high anxiety levels were: living with a person who is elderly (p = 0.01), has a chronic disease (p < 0.0001), has immune deficiency (p < 0.0001), or has a respiratory disease (p-value <0.0001).
    keywords: anxiety; covid-19; hcws; level; pandemic; saudi; study
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        item: #7409 of 7819
          id: cord-351083-3oy7zuy9
      author: Rashid, Sabina Faiz
       title: Towards a socially just model: balancing hunger and response to the COVID-19 pandemic in Bangladesh
        date: 2020-06-01
       words: 2147
      flesch: 48
     summary: Sadly, countries with large pools of poor populations may soon be forced to confront similar trade-offs, with all its moral and ethical implications, if there is no solution soon in sight. poliTiCal CommiTmenT foR eConomiC SuppoRT foR The pooR needS uRgenT and effeCTive implemenTaTion Bangladesh, like many other countries, has rolled out an economic stimulus package to address the severe economic and business fallout from the pandemic.
    keywords: bangladesh; covid-19; food; health; pandemic; poor
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        item: #7410 of 7819
          id: cord-351085-t4rxu2hq
      author: Ortoleva, J.
       title: Intracranial Hemorrhage in COVID-19 Patients on ECMO: Challenges and Future Directions
        date: 2020-06-09
       words: 566
      flesch: 16
     summary: A Single Academic Center Experience in the Epicenter of Disease in the United States Veno-venous Extracorporeal Membrane Oxygenation for Respiratory Failure in COVID-19 Patients: Early Experience From a Major Academic Medical Center in North America In-Hospital Neurologic Complications in Adult Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation: Results From the Extracorporeal Life Support Organization Registry Neurologic Injury in Adults Supported With Veno-Venous Extracorporeal Membrane Oxygenation for Respiratory Failure: Findings From the Extracorporeal Life Support Organization Database Association of Treatment Dose Anticoagulation with In-Hospital Survival Among Hospitalized Patients with COVID-19 ECMO for COVID-19 associated severe ARDS and risk of thrombosis Thrombosis and coagulopathy in COVID-19 patients requiring extracorporeal membrane oxygenation COVID-19 and VTE/Anticoagulation: Frequently Asked Questions Extracorporeal Membrane Oxygenation Induces Short-Term Loss of High-Molecular-Weight von Willebrand Factor Multimers Multi-Modal Characterization of the Coagulopathy Associated With Extracorporeal Membrane Oxygenation None 1 Extracorporeal membrane oxygenation (ECMO) is occasionally being used to support COVID-19 patients refractory to optimal mechanical ventilation, neuromuscular blockade, prone positioning, and inhaled pulmonary vasodilators.
    keywords: covid-19; extracorporeal
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        item: #7411 of 7819
          id: cord-351092-b01o6f69
      author: De Francesco, Maria A.
       title: Pneumocystis jirevocii and SARS-CoV-2 Co-Infection: A Common Feature in Transplant Recipients?
        date: 2020-09-18
       words: 2233
      flesch: 28
     summary: In Roles of Host Gene and Non-Coding RNA Expression in Virus Infection Full spectrum of COVID-19 severity still being depicted Association of radiologic findings with mortality of patients infected with 2019 novel coronavirus in Wuhan, China Understanding of COVID-19 based on current evidence Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study Bacterial and fungal infections in COVID-19 patients: A matter of concern Trained immunity: A tool for reducing susceptibility to and severity of SARS-CoV-2 infection Clinical characteristics of 82 cases of death from COVID-19 Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study Pathological findings of COVID-19 associated with acute respiratory distress syndrome HOPS Investigators. In this reported case, the patient was an 83-year-old female non-smoker, who did not have an underlying immunodeficiency nor any classical risk for Pneumocystis infection.
    keywords: covid-19; infection; jirevocii; patients; pneumocystis; pneumonia; sars
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        item: #7412 of 7819
          id: cord-351101-l8b2cv4z
      author: Uppuluri, Ellen M
       title: Development of pulmonary embolism in a nonhospitalized patient with COVID-19 who did not receive venous thromboembolism prophylaxis
        date: 2020-08-11
       words: 2170
      flesch: 34
     summary: National Institutes of Health website Prevention, diagnosis and treatment of venous thromboembolism in patients with COVID-19: CHEST guideline and expert panel report Implementation of a direct oral anticoagulation screening service at a large academic medical center provided by a pharmacist-managed antithrombosis clinic as a method to expand antithrombotic stewardship efforts Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Incidence of venous thromboembolism in hospitalized patients with COVID-19 Pulmonary embolism in COVID-19 patients: awareness of an increased prevalence Blood coagulation, fibrinolysis and cellular haemostasis: venous thromboembolic events in hospitalized medical patients Pulmonary embolism: a complication of COVID 19 infection Rivaroxaban for thromboprophylaxis in acutely ill medical patients Extended thromboprophylaxis with betrixaban in acutely ill medical patients Rivaroxaban for thromboprophylaxis after hospitalization for medical illness American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients Prevention of VTE in nonsurgical patients: antithrombotic therapy and prevention of thrombosis Considerations in prophylaxis and treatment of VTE in COVID-19 patients Search result ISTH interim guidance on recognition and management of coagulopathy in COVID-19 COVID-19 and thrombotic or thromboembolic disease: implications for prevention, antithrombotic therapy, and follow-up Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the Anticoagulation Forum COVID-19) treatment guidelines.
    keywords: covid-19; patients; prophylaxis; risk; vte
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        item: #7413 of 7819
          id: cord-351108-wfik975q
      author: Cherry, George
       title: Loss of smell and taste: a new marker of COVID-19? Tracking reduced sense of smell during the coronavirus pandemic using search trends
        date: 2020-07-16
       words: 3656
      flesch: 55
     summary: Using search interest data to infer population-wide behavior in developed countries has recently become possible. Search interest data were aggregated on a daily basis within the period of interest.
    keywords: cases; covid-19; data; interest; loss; search; sense; smell
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        item: #7414 of 7819
          id: cord-351116-jwy6k0ih
      author: O'Reilly, GM
       title: Epidemiology and clinical features of emergency department patients with suspected and confirmed COVID‐19: A multisite report from the COVED Quality Improvement Project for July 2020 (COVED‐3)
        date: 2020-09-21
       words: 3599
      flesch: 43
     summary: In this prospective multi‐site study from July 2020, a substantial proportion of ED patients required SARS‐CoV‐2 testing, isolation and enhanced infection prevention and control precautions. Although the clinical features of COVID-19 are well described, relatively little has been published about the characteristics of ED patients who undergo testing for SARS-CoV-2.
    keywords: covid-19; data; hospital; patients; sars; study; test
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        item: #7415 of 7819
          id: cord-351129-lzzyn570
      author: Lee, Jae-Hyun
       title: Management of Allergic Patients During the COVID-19 Pandemic in Asia
        date: 2020-06-15
       words: 3418
      flesch: 40
     summary: Coronavirus disease 2019 in Children -United States Intranasal corticosteroids in allergic rhinitis in COVID-19 infected patients: an ARIA-EAACI statement Atopic dermatitis: Collegium Internationale Allergologicum (CIA) update 2019 Recurrent eczema herpeticum -a retrospective European multicenter study evaluating the clinical characteristics of eczema herpeticum cases in atopic dermatitis patients Safety of dupilumab in severe atopic dermatitis and infection of COVID-19: two case reports The diagnosis and management of acute and chronic urticaria: 2014 update Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Risk factors of critical & mortal COVID-19 cases: a systematic literature review and meta-analysis Inpatient care of patients with COVID-19: a guide for hospitalists The use of biologics for immune modulation in allergic disease COVID-19 in a MS patient treated with ocrelizumab: does immunosuppression have a protective role However, most of the biologics require periodic parenteral/subcutaneous administration, for which such patients have to visit an allergy clinic to receive medications according to a treatment protocol.
    keywords: asthma; children; covid-19; disease; pandemic; patients; risk; treatment
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        item: #7416 of 7819
          id: cord-351142-g20f6bxc
      author: Kiaghadi, Amin
       title: Assessing COVID-19 risk, vulnerability and infection prevalence in communities
        date: 2020-10-29
       words: 6787
      flesch: 42
     summary: While Harris County was experiencing fewer cases, and lower rates of transmission relative to the rest of the U.S., starting around mid-June 2020, the pandemic resurged, and the number of COVID-19 cases has increased substantially. To the best of the knowledge of the authors, none of the existing studies provide a holistic perspective on COVID-19 vulnerability.
    keywords: cases; census; county; covid-19; data; fig; harris; health; number; population; risk; total; tract; vulnerability
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        item: #7417 of 7819
          id: cord-351155-5bvo66yb
      author: Kushner, Tatyana
       title: Chronic Liver Disease and COVID‐19: Alcohol Use Disorder/Alcohol‐Associated Liver Disease, Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis, Autoimmune Liver Disease, and Compensated Cirrhosis
        date: 2020-05-21
       words: 1807
      flesch: 32
     summary: 21 Our knowledge of the impact of chronic liver disease on risk and severity of COVID-19 infection, as well as understanding of the COVID-19 pandemic and effect on hepatic disease, will continue to evolve. There are several key issues surrounding COVID-19 infection in patients with cirrhosis, including potentially increased risk for SARS-CoV-2 infection, higher risk for severe disease, and increased risk for hepatic decompensation (Fig. 1) .
    keywords: covid-19; disease; liver; patients; risk
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        item: #7418 of 7819
          id: cord-351166-0pajmek3
      author: Kligerman, Maxwell P.
       title: Challenges Facing Otolaryngologists in Low- and Middle-Income Countries During the COVID-19 Pandemic
        date: 2020-08-18
       words: 1476
      flesch: 46
     summary: [11] As a result, many otolaryngologists in LMICs are left to purchase their own PPE at exorbitant prices or simply risk inadequate protection. [4, 5] Economic and infrastructural limitations in many LMICs have rendered implementation of these policies extremely difficult if not impossible for local otolaryngologists and healthcare officials.
    keywords: countries; covid-19; lmics; otolaryngologists
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        item: #7419 of 7819
          id: cord-351184-kcc3p3ow
      author: Dotters-Katz, Sarah K.
       title: Considerations for Obstetric Care during the COVID-19 Pandemic
        date: 2020-04-17
       words: 3827
      flesch: 47
     summary: [The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China] (in Chinese) Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an openlabel non-randomized clinical trial A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 Middle east respiratory syndrome coronavirus (MERS-CoV) infection during pregnancy: report of two cases & review of the literature Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome The association between seasonal influenza-like illness cases and foetal death: a time series analysis Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia A case of 2019 Novel Coronavirus in a pregnant woman with preterm delivery Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy Available at Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study Clinical analysis of pregnant women with 2019 novel coronavirus pneumonia COVID-19 in pregnancy: early lessons COVID-19 and Obstetric Care Dotters-Katz Maternal influenza and birth outcomes: systematic review of comparative studies Impact of Middle East Respiratory Syndrome coronavirus (MERS-CoV) on pregnancy and perinatal outcome Extracorporeal life support during pregnancy Maternal and infant outcomes among severely ill pregnant and postpartum women with 2009 pandemic influenza A (H1N1)-United States Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan, China Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn Outpatient Assessment and Management for Pregnant Women With Suspected or Confirmed Novel Coronavirus (COVID-19) American College of Obstetricians and Gynecologists; Public Health Preparedness Expert Work Group. Some centers are not allowing any support persons on labor and delivery units, while others only completely restrict visitation for PUI or confirmed COVID-19 patients.
    keywords: care; cases; covid-19; delivery; infection; patients; pregnancy; risk; women
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        item: #7420 of 7819
          id: cord-351187-kxouck2q
      author: Cothran, Thomas P.
       title: A Brewing Storm: The Neuropsychological Sequelae of Hyperinflammation due to COVID-19
        date: 2020-06-23
       words: 707
      flesch: 17
     summary: Rapid progression to acute respiratory distress syndrome: Review of current understanding of critical illness from COVID-19 infection Brain atrophy and cognitive impairment in survivors of acute respiratory distress syndrome COVID-19: ICU delirium management during SARS-CoV-2 pandemic Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Intubation and ventilation amid the COVID-19 outbreak Hematological findings and complications of COVID-19 Are we facing a crashing wave of neuropsychiatric sequelae of COVID-19? W. Tam To the Editor, There has been significant focus on understanding COVID-19 symptoms and identifying possible treatments during the current pandemic.
    keywords: covid-19
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        item: #7421 of 7819
          id: cord-351189-56am76lb
      author: Rosen, Melissa H
       title: Management of Acute Severe Ulcerative Colitis in a Pregnant Woman With COVID-19 Infection: A Case Report and Review of the Literature
        date: 2020-05-12
       words: 2376
      flesch: 42
     summary: Optimal management of immunosuppression in inflammatory bowel disease (IBD) patients with COVID-19 infection currently is based on expert opinion, given the novelty of the infection and the corresponding lack of high-level evidence in patients with immune-mediated conditions. Optimal management of immunosuppression in inflammatory bowel disease (IBD) patients with COVID-19 infection currently is based on expert opinion, given the novelty of the infection and the corresponding lack of high-level evidence in patients with immune-mediated conditions.
    keywords: covid-19; cyclosporine; disease; patients; pregnancy; sars
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        item: #7422 of 7819
          id: cord-351238-epw9w7xx
      author: Huang, Xing
       title: In Reply: Precautions for Endoscopic Transnasal Skull Base Surgery During the COVID-19 Pandemic
        date: 2020-04-17
       words: 919
      flesch: 44
     summary: Owing to the striking increase of COVID-19 cases, the safety of medical workers is a concern. Because the virus exists in all parts of the respiratory tract, there is a heated discussion on the timing of surgical treatment of respiratory diseases, especially the safety assessment of endoscopic transsphenoidal surgery in the department of neurosurgery.
    keywords: covid-19; surgery; workers
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        item: #7423 of 7819
          id: cord-351246-0kjqrf06
      author: Zahnd, Whitney E.
       title: The COVID‐19 Pandemic Illuminates Persistent and Emerging Disparities among Rural Black Populations
        date: 2020-05-03
       words: 388
      flesch: 51
     summary: The South, where 94% of black rural populations live, has the perfect storm of more lax stay at home and social distancing policies, higher rates of underlying conditions, and lack of access to health care services, inviting racial disparities in COVID-19 cases and deaths to be even more stark in rural communities. 6 Finally, most states that have yet to expand Dr. Fauci rightly notes that the coronavirus pandemic shines a bright light on racial disparities, but let us work and hope that the big city lights do not blind the world to both the persistent and emerging disparities experienced by rural black populations.
    keywords: rural
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        item: #7424 of 7819
          id: cord-351273-tfmq085x
      author: Zhou, Bo
       title: A Case of Coronavirus Disease 2019 With Concomitant Acute Cerebral Infarction and Deep Vein Thrombosis
        date: 2020-04-22
       words: 2395
      flesch: 41
     summary: Patients with COVID-19 are in a hypercoagulable state, with blood stasis and endothelial injury due to inflammation; in addition, most elderly patients with severe COVID-19 have a previous medical history of hypertension and atherosclerosis (1) (2) (3) (4) . Thus, arterial and venous thrombosis should be considered and promptly managed in patients with severe COVID-19.
    keywords: covid-19; day; patient; thrombosis
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        item: #7425 of 7819
          id: cord-351276-eatlugrm
      author: Pinna, Graziano
       title: Sex and COVID-19: A protective role for reproductive steroids
        date: 2020-11-09
       words: 2353
      flesch: 24
     summary: Intriguingly, progesterone binds to progesterone receptors in immune cells, including natural killer cells, T cells, macrophages, and dendritic cells but can also bind non-immune cells, including epithelial and endothelial cells in the respiratory tracts where it alters cellular signaling/activity improving infections. Female reproductive steroids, estrogen and progesterone and its metabolite, allopregnanolone are anti-inflammatory, reshape competence of immune cells, stimulate antibody production and promote proliferation and respiratory epithelial cell repair suggesting they may protect against COVID-19 symptoms.
    keywords: allopregnanolone; cells; covid-19; progesterone; tlr4; women
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        item: #7426 of 7819
          id: cord-351280-13vz8rg8
      author: Dubicka, Bernadka
       title: Editorial: How in the world are we handling COVID‐19?
        date: 2020-08-18
       words: 1454
      flesch: 45
     summary: Stigma attached to mental health issues remains strong, further compounding access and availability of services, potentially leaving many vulnerable children in longterm distress. Perhaps counterintuitively, given the expected increase in mental health problems, Ougrin (2020) reports that emergency room visits in general, and for self-harm in particular, dramatically declined.
    keywords: covid-19; debate; health; pandemic
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        item: #7427 of 7819
          id: cord-351305-6vtv2xuh
      author: Schramm, Markus A.
       title: COVID-19 in a Severely Immunosuppressed Patient With Life-Threatening Eosinophilic Granulomatosis With Polyangiitis
        date: 2020-08-28
       words: 1264
      flesch: 29
     summary: American College of Rheumatology Guidance for the Management of Adult Patients with Rheumatic Disease During the COVID-19 Pandemic Temporal dynamics in viral shedding and transmissibility of COVID-19 Virological assessment of hospitalized patients with COVID-2019 Long-term coexistence of SARS-CoV-2 with antibody response in COVID-19 patients The potential danger of suboptimal antibody responses in COVID-19 Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection This work was supported by the German Research Foundation (DFG): TRR 130, project 12 to RV. Front Immunol DOI: 10.3389/fimmu.2020.02086 sha: doc_id: 351305 cord_uid: 6vtv2xuh Immunosuppressive therapies increase the susceptibility of patients to infections.
    keywords: cov-2; covid-19; patient; sars
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        item: #7428 of 7819
          id: cord-351340-7y19ystp
      author: Rao, Gundu H. R.
       title: Coronavirus Disease and Acute Vascular Events
        date: 2020-07-31
       words: 2561
      flesch: 38
     summary: They found that circulatory and endocrine comorbidities were common among COVID-19 patients, leading to the conclusion that circulatory diseases remained the most common category of comorbidities. Studies of COVID-19 patients in Wuhan, China, demonstrated that D-dimer levels upon admission >2.0 mg/mL effectively predicted in-hospital mortality.
    keywords: coronavirus; covid-19; disease; infection; injury; patients; sars
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        item: #7429 of 7819
          id: cord-351343-zdh8ms1z
      author: Din, Anwarud
       title: STATIONARY DISTRIBUTION AND EXTINCTION OF STOCHASTIC CORONAVIRUS (COVID-19) EPIDEMIC MODEL
        date: 2020-06-24
       words: 4223
      flesch: 59
     summary: Stochastic models possess some inherent randomness. Numerous approaches and methods exist for studying stochastic models (such as Binomial moment equation etc.)
    keywords: covid-19; model; stochastic
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        item: #7430 of 7819
          id: cord-351348-lzo0dz7z
      author: Gu, Silan
       title: Alterations of the Gut Microbiota in Patients with COVID-19 or H1N1 Influenza
        date: 2020-06-04
       words: 1996
      flesch: 42
     summary: This cross-sectional study analyzed the gut microbiome of COVID-19 patients, H1N1 patients, and healthy controls (HC) by high-throughput sequencing of the 16S rRNA gene to provide a theoretical basis for differential diagnosis and intestinal microbial intervention. Patients with H1N1 displayed lower diversity and different overall microbial composition compared with COVID-19 patients.
    keywords: covid-19; gut; h1n1; patients
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        item: #7431 of 7819
          id: cord-351369-ugba8uah
      author: Gao, Wenqi
       title: A newborn with normal IgM and elevated IgG antibodies born to an asymptomatic infection mother with COVID-19
        date: 2020-09-11
       words: 1418
      flesch: 58
     summary: On March 9, 2020 the nucleic acid test of neonatal COVID-19 pharyngeal swab was negative, however, and serum COVID-19 IgM and IgG antibodies were normal and strong positive, respectively. June 17, 2020 about one hundred days after the neonate was born, we detected the serum COVID-19 IgM and IgG antibodies of mother and infant again.
    keywords: covid-19; igg; igm; march
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        item: #7432 of 7819
          id: cord-351407-7vx9lzi0
      author: Mehta, Puja
       title: JAK inhibitors in COVID-19: need for vigilance regarding increased inherent thrombotic risk
        date: 2020-07-06
       words: 1252
      flesch: 24
     summary: We recommend risk mitigation strategies including consideration of exclusion of patients with high thrombotic risk, treatment with standard or intermediate-dose low molecular weight heparin prophlyaxis 7 during hospitalisation and consideration of increased thrombotic risk associated with JAKi, given the hypercoagulability of COVID-19. Although it was initially thought that insidious venous thromboembolic events (VTE) were mainly confined to ventilated patients [3], we now understand thrombotic risk to be a wider problem in COVID-19.
    keywords: covid-19; jaki; patients
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        item: #7433 of 7819
          id: cord-351430-bpv7p7zo
      author: Pequeno, Pedro
       title: Air transportation, population density and temperature predict the spread of COVID-19 in Brazil
        date: 2020-06-03
       words: 4789
      flesch: 37
     summary: We evaluated the effect of meteorological conditions (temperature, solar radiation, air humidity and precipitation) on 292 daily records of cumulative number of confirmed COVID-19 cases across the 27 Brazilian capital cities during the 1st month of the outbreak, while controlling for an indicator of the number of tests, the number of arriving flights, population density, proportion of elderly people and average income. Therefore, we performed two versions of the above analysis: one including all predictors but excluding days for which precipitation was lacking (n = 269) and another one excluding precipitation as predictor and using all counts of confirmed COVID-19 cases (n = 292).
    keywords: cases; cities; covid-19; mean; number; predictors; temperature; time
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        item: #7434 of 7819
          id: cord-351431-xcqz9d3t
      author: Wang, Jun
       title: Excessive Neutrophils and Neutrophil Extracellular Traps in COVID-19
        date: 2020-08-18
       words: 4524
      flesch: 41
     summary: The laboratory test of each patient on the day of hospital admission showed that the median neutrophil count in severe COVID-19 patients (3.4, IQR: 1.8-6.7) was higher than in the moderate (3.0, 2.4-3.6) and mild (2.9, 2.3-3.5) groups. In contrast, lymphocyte and monocyte counts in severe COVID-19 patients were lower than in the other two groups ( Principal component analysis was performed to visualize the contribution of all mentioned clinical parameters on disease severity (Figure 2A) .
    keywords: analysis; cases; cells; counts; covid-19; figure; genes; lung; nets; neutrophil; patients
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        item: #7435 of 7819
          id: cord-351446-j4ambec5
      author: Sinonquel, P.
       title: COVID‐19 and gastrointestinal endoscopy: what should be taken into account?
        date: 2020-04-26
       words: 2675
      flesch: 40
     summary: We recommend these 'assistants' to be experienced In low risk or confirmed COVID-19 negative patients this buddy system is not required and the endoscopist can be assisted by one (or more) endoscopic nurse without taking the enhanced but only the standard PPE and infection control measures. Low risk patients are patients with no risk factors and no symptoms or at least 1 positive risk factor but a negative laboratory RT-PCR test.
    keywords: cov-2; covid-19; endoscopy; patient; procedure; risk; sars
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        item: #7436 of 7819
          id: cord-351492-8jv7ip67
      author: Urwin, S. G.
       title: FebriDx point-of-care test in patients with suspected COVID-19: a pooled diagnostic accuracy study
        date: 2020-10-20
       words: 7244
      flesch: 42
     summary: We aimed to undertake a systematic review and pooled diagnostic test accuracy study of available individual patient data (IPD) to evaluate the diagnostic accuracy of a commercial POC test (FebriDx) in patients with suspected COVID-19. We undertook a systematic review and pooled diagnostic test accuracy study of available individual patient data (IPD) to evaluate the diagnostic accuracy of the FebriDx LFD compared to contemporaneous reverse transcriptase polymerase chain reaction (RT-PCR) testing to understand the performance of FebriDx in the identification of patients with COVID-19.
    keywords: accuracy; covid-19; febridx; medrxiv; patients; preprint; results; review; studies; study; test
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        item: #7437 of 7819
          id: cord-351509-aau3gx6f
      author: Li, Yuman
       title: Prognostic Value of Right Ventricular Longitudinal Strain in Patients with COVID-19
        date: 2020-04-28
       words: 3459
      flesch: 35
     summary: Therefore, comprehensive assessment of RV function using 2D-STE may be essential for risk stratification in COVID-19 patients. Therefore, evaluation of RV function should be implemented by investigation of RVLS for risk stratification in COVID-19 patients.
    keywords: covid-19; echocardiography; function; patients; rvls; study; ventricular
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        item: #7438 of 7819
          id: cord-351510-8m4930bc
      author: Aquino, Yves S J
       title: Hydroxychloroquine and COVID-19: critiquing the impact of disease public profile on policy and clinical decision-making
        date: 2020-07-09
       words: 5068
      flesch: 42
     summary: As various expert panels and bodies have highlighted the threat to the HCQ supply for lupus patients generated by HCQ use in the treatment of COVID-19, 8 media reports of unusual prescribing patterns on the part of healthcare providers have emerged. key: cord-351510-8m4930bc authors: Aquino, Yves S J; Cabrera, Nicolo title: Hydroxychloroquine and COVID-19: critiquing the impact of disease public profile on policy and clinical decision-making date: 2020-07-09 journal: J Med Ethics DOI: 10.1136/medethics-2020-106306 sha: doc_id: 351510 cord_uid: 8m4930bc The controversy surrounding the use of hydroxychloroquine (HCQ), an antimalarial drug, for COVID-19 has raised numerous ethical and policy problems.
    keywords: case; consent; covid-19; disease; evidence; hcq; label; patients; profile; treatment; use
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        item: #7439 of 7819
          id: cord-351512-h4vigeuy
      author: Zhang, Lin
       title: How scientific research reacts to international public health emergencies: a global analysis of response patterns
        date: 2020-06-09
       words: 7125
      flesch: 43
     summary: As Fig. 15 shows, China, as the heart of the outbreak in the initial period, has taken a prominent role in COVID-19 research with the largest number of publications, followed by the USA and the UK. Apart from Canada and European countries, the USA also collaborated intensively with several African countries on Ebola research, such as Sierra Leone, Liberia, Guinea etc., which are the main areas of the Ebola outbreak.
    keywords: china; countries; covid-19; disease; ebola; emergencies; funding; health; number; outbreak; publications; research; sars
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        item: #7440 of 7819
          id: cord-351528-23lbs8al
      author: Zacharia, Brad E
       title: Letter: Surgical Management of Brain Tumor Patients in the COVID-19 Era
        date: 2020-04-29
       words: 1000
      flesch: 28
     summary: Expeditious but safe discharges can conserve hospital beds for COVID-19 patients. In regions with high baseline COVID-19 rates and available testing, all patients should undergo testing as close as possible to surgery.
    keywords: airway; covid-19; patients; testing
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        item: #7441 of 7819
          id: cord-351555-hsgsuor2
      author: Constantinou, Constantina
       title: Developing a holistic contingency plan: Challenges and dilemmas for cancer patients during the COVID‐19
        date: 2020-07-20
       words: 7598
      flesch: 41
     summary: key: cord-351555-hsgsuor2 authors: Constantinou, Constantina; Kolokotroni, Ourania; Mosquera, Maria‐Cecilia; Heraclides, Alexandros; Demetriou, Christiana; Karayiannis, Peter; Quattrocchi, Annalisa; Charalambous, Andreas title: Developing a holistic contingency plan: Challenges and dilemmas for cancer patients during the COVID‐19 date: 2020-07-20 journal: Cancer Med DOI: 10.1002/cam4.3271 sha: doc_id: 351555 cord_uid: hsgsuor2 During the first quarter of 2020 the world is experiencing a pandemic of Severe Acute Respiratory Syndrome‑Coronavirus‑2 (SARS‑CoV‑2), a novel beta coronavirus that is responsible for the 2019 novel coronavirus disease (COVID‐19). The COVID‐19 pandemic revealed that healthcare systems around the world were not prepared to deal with either the direct effects of the pandemic or with the indirect effects that are imposed on the health of patients with chronic disorders such as cancer patients.
    keywords: addition; cancer; cancer patients; care; coronavirus; covid-19; disease; healthcare; management; pandemic; patients; risk; sars; treatment
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        item: #7442 of 7819
          id: cord-351567-ifoe8x28
      author: Rabi, Firas A.
       title: SARS-CoV-2 and Coronavirus Disease 2019: What We Know So Far
        date: 2020-03-20
       words: 5766
      flesch: 49
     summary: Initial virological and clinical findings Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses Controlled Trial of Ebola Virus Disease Therapeutics Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro First Case of 2019 Novel Coronavirus in the United States NIH Clinical Trial of Remdesivir to Treat COVID-19 Begins Gilead Sciences Initiates Two Phase 3 Studies of Investigational Antiviral Remdesivir for the Treatment of COVID-19 Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Protease inhibitors targeting coronavirus and filovirus entry Camostat Mesilate, Pancrelipase, and Rabeprazole Combination Therapy Improves Epigastric Pain in Early Chronic Pancreatitis and Functional Dyspepsia with Pancreatic Enzyme Abnormalities TACTIC Investigative Team a phase 1/2 trial to evaluate the pharmacokinetics, safety, and efficacy of NI-03 in patients with chronic pancreatitis: Study protocol for a randomized controlled trial on the assessment of camostat treatment in chronic pancreatitis (TACTIC) However, by that time, travelers had carried the virus to many countries, sparking memories of the previous coronavirus epidemics, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), and causing widespread media attention and panic.
    keywords: cases; china; coronavirus; cov-2; covid-19; disease; novel; number; patients; risk; sars; wuhan
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        item: #7443 of 7819
          id: cord-351580-129608e4
      author: Shen, J.
       title: A Recursive Bifurcation Model for Predicting the Peak of COVID-19 Virus Spread in United States and Germany
        date: 2020-04-14
       words: 1859
      flesch: 52
     summary: key: cord-351580-129608e4 authors: Shen, J. title: A Recursive Bifurcation Model for Predicting the Peak of COVID-19 Virus Spread in United States and Germany date: 2020-04-14 journal: nan DOI: 10.1101/2020.04.09.20059329 sha: doc_id: 351580 cord_uid: 129608e4 Prediction on the peak time of COVID-19 virus spread is crucial to decision making on lockdown or closure of cities and states. The bifurcation pattern of infected population is given in Figure 4 (a) and the determination of virus spread rate is presented in Figure 4 (b).
    keywords: cycle; population; spread; virus
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        item: #7444 of 7819
          id: cord-351584-380s4j70
      author: Ward, Michael P.
       title: The role of climate during the COVID‐19 epidemic in New South Wales, Australia
        date: 2020-06-01
       words: 2256
      flesch: 34
     summary: In one of the first studies of its type, based on the daily count of COVID-19 cases in 30 Chinese provinces Qi et al. (2020) found significant negative associations between cases and average temperature and relative humidity. In the current study, our aim was to further investigate the relationship between reports of COVID-19 cases during the early epidemic phase in NSW, Australia and temperature and relative humidity.
    keywords: a.m.; cases; covid-19; humidity; temperature
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        item: #7445 of 7819
          id: cord-351593-84xpllwh
      author: Shaw, Jane A.
       title: Lung Ultrasound in COVID-19: Not Novel, but Necessary
        date: 2020-07-13
       words: 1293
      flesch: 47
     summary: Lung ultrasound is by no means a novel diagnostic lungimaging modality. Lung ultrasound has been used as a tool for monitoring COVID-19 patients from home [11] .
    keywords: chest; covid-19; lung; ultrasound
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        item: #7446 of 7819
          id: cord-351600-bqw9ks4a
      author: Zhang, Shuai
       title: Development and validation of a risk factor-based system to predict short-term survival in adult hospitalized patients with COVID-19: a multicenter, retrospective, cohort study
        date: 2020-07-16
       words: 4972
      flesch: 42
     summary: In patients with COVID-19, plasma LDH level was reported to be higher in severe, ICU, and deceased COVID-19 patients than in mild, non-ICU-patients, and survivors In this study, we employed the clinical and laboratory features of COVID-19 patients to work out an effective and easy tool for predicting 28-day mortality.
    keywords: cohort; covid-19; day; hospital; mortality; patients; study; survival; wuhan
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        item: #7447 of 7819
          id: cord-351604-x4rsdwqz
      author: González-Gay, Miguel A.
       title: BioLogic THERAPY IN COVID-19
        date: 2020-06-26
       words: 1503
      flesch: 32
     summary: In summary, based on our experience in the management of autoimmune diseases with biologic therapies and new small molecules, we strongly support the use of these agents in COVID-19 patients with severe disease or in those patients who experience a rapid deterioration due to the development of a MAS-like hyperinflammatory state. Since the antiinflammatory effect of IVIg predominates over its immunosuppressive effect 15 , as occurred with autoimmune diseases where it is difficult to establish a differential diagnosis between autoinflammatory/autoimmune disease and intercurrent infections, IVIg therapy may be considered in COVID-19 patients with bacterial superinfection associated.
    keywords: anti; covid-19; disease; patients; syndrome
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        item: #7448 of 7819
          id: cord-351625-1we9wi1g
      author: Han, Huan
       title: Descriptive, Retrospective Study of the Clinical Characteristics of Asymptomatic COVID-19 Patients
        date: 2020-10-07
       words: 4069
      flesch: 42
     summary: These results suggest that asymptomatic COVID-19 patients had normal clinical indicators and faster viral clearance than symptomatic patients. Our results demonstrate that asymptomatic COVID-19 patients have better outcomes than symptomatic patients.
    keywords: asymptomatic; cell; counts; covid-19; disease; liver; patients; sars
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        item: #7449 of 7819
          id: cord-351644-pl7xpivx
      author: Gao, Yelei
       title: Application of Telemedicine During the Coronavirus Disease Epidemics: A Rapid Review and Meta-Analysis
        date: 2020-04-17
       words: 4722
      flesch: 51
     summary: The quality of included studies was very poor: all studies scored less than 8 out of 11 in the evaluation by the AHRQ tool ( Table 2) . Our study showed that among the people who need consultation, COVID-19 patients were most concerned about symptoms, the epidemic situation and public problems related to the disease, whereas SARS patients were most concerned about symptoms, prevention and treatment, and psychological problems.
    keywords: funder; holder; license; medrxiv; peer; preprint; sars; studies; topic
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        item: #7450 of 7819
          id: cord-351662-rmkcb6o3
      author: Huang, Zhifeng
       title: Characteristics and roles of SARS‐CoV‐2 specific antibodies in patients with different severities of COVID‐19
        date: 2020-07-24
       words: 2869
      flesch: 51
     summary: COVID-19 patients had significantly more symptoms of fever, wheezing, and fatigue than non-COVID-19 patients (P<0.01). The chest CTs of COVID-19 patients all revealed suspected viral pneumonia.
    keywords: covid-19; iga; igg; igm; levels; patients
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        item: #7451 of 7819
          id: cord-351665-6gwb900b
      author: Sarkar, Priyanka
       title: Coupled human-environment system amid COVID-19 crisis: A conceptual model to understand the nexus
        date: 2020-08-18
       words: 5723
      flesch: 37
     summary: UNDP Latin America and the Caribbean Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science Enhanced secondary pollution offset reduction of primary emissions during COVID-19 lockdown in China Development of conceptual models for major social and ecological systems in the South East NRM Region Another Crisis In The Making: COVID-19 and India's Bio-Medical Waste Coronavirus in India: Tablighi Jamaat meet turns Covid-19 super spreader Coronavirus: A visual guide to the economic impact COVID-19 lockdown a blessing for the endangered Gangetic dolphin in Bihar: Experts, DownToEarth The Pandemic Is Turning the Natural World Upside Down The effect of human mobility and control measures on the COVID-19 epidemic in China COVID-19 and the nature trade-off paradigm COVID-19: Water scarcity lurking in crisis? Poverty and food insecurity could grow dramatically as COVID-19 spreads The economic impact of the Coronavirus 2019 (Covid-2019): Implications individual reaction and governmental action Health risks and potential remedies during prolonged lockdowns for coronavirus disease Complexity of coupled human and natural systems Sanitation Workers At Risk From Discarded Medical Waste Related To Covid-19 Mass gathering events and reducing further global spread of COVID-19: a political and public health dilemma If we get food right, we get everything right: rethinking the food system in post-COVID-19 Hawai'i COVID-19 pandemic and environmental pollution: A blessing in disguise Emerging threats to human health from global environmental change Impact of the coronavirus pandemic on the world economy Last accessed on Spillover of COVID-19: impact on the Global Economy Inter nation social lockdown versus medical care against COVID-19, a mild environmental insight with special reference to India Initial evidence of higher morbidity and mortality due to SARS-CoV-2 in regions with lower air quality Assessing Vulnerabilities to the Effects of Global Change: An Eight-Step Approach. key: cord-351665-6gwb900b authors: Sarkar, Priyanka; Debnath, Nirmal; Reang, Demsai title: Coupled human-environment system amid COVID-19 crisis: A conceptual model to understand the nexus date: 2020-08-18 journal: Sci Total Environ DOI: 10.1016/j.scitotenv.2020.141757 sha: doc_id: 351665 cord_uid:
    keywords: covid-19; crisis; environment; et al; human; impacts; lockdown; model; pandemic; society
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        item: #7452 of 7819
          id: cord-351666-q7dqsl7n
      author: Milani, Fabio
       title: COVID-19 outbreak, social response, and early economic effects: a global VAR analysis of cross-country interdependencies
        date: 2020-08-19
       words: 9184
      flesch: 50
     summary: Social distancing responses to domestic and global health shocks are heterogeneous; however, they almost always exhibit delays and sluggish adjustments. Gupta and et al. (2020) find that social distancing responses do not necessarily correspond to policies mandated by State and local governments.
    keywords: cases; coronavirus; countries; country; covid-19; data; distancing; global; mobility; perceptions; responses; risk; unemployment; variables
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        item: #7453 of 7819
          id: cord-351672-7oi9w87s
      author: Klemeš, Jiří Jaromír
       title: COVID‐19 pandemic facilitating energy transition opportunities
        date: 2020-09-30
       words: 2671
      flesch: 47
     summary: However, there have not been only issues which are leading in the post-pandemic period to increase energy consumption. Figure 1 shows the source of energy consumption of IoT development, including data centre (main contributor), machine to machine communications, obsolescence of digital technologies and embodied energy.
    keywords: consumption; covid-19; data; efficiency; energy; example; new; pandemics
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        item: #7454 of 7819
          id: cord-351689-nyfsv357
      author: Borghesi, Andrea
       title: COVID-19 Pneumonia: Three Thoracic Complications in the Same Patient
        date: 2020-07-20
       words: 2317
      flesch: 38
     summary: A study of 302 patients from Italy Radiographic findings in 240 patients with COVID-19 pneumonia: Time-dependence after the onset of symptoms Acute pulmonary embolism in non-hospitalized COVID-19 patients referred to CTPA by emergency department Acute pulmonary embolism in a patient with COVID-19 pneumonia SARS-CoV-2 Infection with Different Radiological Insights COVID-19 with spontaneous pneumothorax, pneumomediastinum and subcutaneous emphysema Spontaneous pneumothorax and subcutaneous emphysema in COVID-19 patient: Case report Tension pneumothorax in a patient with COVID-19 Secondary tension pneumothorax in a COVID-19 pneumonia patient: A case report This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license While acute pulmonary embolism is not a rare finding in patients with COVID-19 pneumonia, the prevalence of pulmonary fibrosis remains unclear.
    keywords: covid-19; day; patient; pulmonary
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        item: #7455 of 7819
          id: cord-351691-3egwvb59
      author: Elzupir, Amin O.
       title: Caffeine and caffeine-containing pharmaceuticals as promising inhibitors for 3-chymotrypsin-like protease of SARS-CoV-2
        date: 2020-10-23
       words: 2954
      flesch: 42
     summary: Of these tested substances were chloroquine phosphate, Remdesivir, Indinavir, Lopinavir, Carfilzomib, Eravacycline, Elbasvir, Valrubicin, Darunavir, Favipiravir isoflavone, myricitrin, a-ketoamides and methyl rosmarinate (Ahmad et al., in press; Beck et al., 2020; Chang, Tung et al., 2020; Das et al., in press; Duan et al., 2020; Ul Qamar et al., 2020; Wahedi et al., in press; Wang, 2020; Wu, Liu et al., 2020) . The RNA genomes of SARS-CoV-2 were found to be identical to about 82% of the SARS-CoV genomes (Enayatkhani et al., in press; Lu et al., 2020; Wu, Liu et al., 2020; Zhou et al., 2020; Zhu et al., 2020) .
    keywords: 3cps; caffeine; coronavirus; covid-19; drugs; et al; pro; sars
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        item: #7456 of 7819
          id: cord-351718-sf5zp5wg
      author: Kohli, Utkarsh
       title: COVID-19 pneumonia in an infant with a hemodynamically significant ventricular septal defect
        date: 2020-10-12
       words: 1377
      flesch: 29
     summary: Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington state Acute heart failure in multisystem inflammatory syndrome in children (MIS-C) in the context of global SARS-CoV-2 pandemic Risk factors for hospitalized respiratory syncytial virus disease and its severe outcomes SARS-CoV-2: a potential novel etiology of fulminant myocarditis Multisystem inflammatory syndrome in children in New York state Risk factors for influenza virus related severe lower respiratory tract infection in children Multisystem inflammatory syndrome in U.S. children and adolescents Respiratory tract infection and risk of hospitalization in children with congenital heart defects during season and off-season: a Swedish National Study SARS-CoV-2 infection in children First reported case of unrepaired tetralogy of Fallot complicated with Coronavirus Disease-19 (COVID-19) Characteristics and outcomes of children with coronavirus disease 2019 (COVID-19) infection admitted to US and Canadian Pediatric Intensive Care Units The cardiovascular burden of coronavirus disease 2019 (COVID-19) with a focus on congenital heart disease Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Clinical and CT features in pediatric patients with COVID-19 infection: different points from adults Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore Clinical characteristics of children with coronavirus disease Financial support. [7] [8] [9] [10] [11] Adults with underlying cardiovascular disease, however, have been found to sustain cardiorespiratory damage leading to increased morbidity and mortality due to COVID-19 infection.
    keywords: children; covid-19; disease; heart
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        item: #7457 of 7819
          id: cord-351719-xqmir1ca
      author: Olaimat, Amin N.
       title: Food Safety During and After the Era of COVID-19 Pandemic
        date: 2020-08-04
       words: 3909
      flesch: 43
     summary: Recently, data on the survival of SARS-CoV-2 on contact surfaces has been reported, but there is none on the survival of COVID-19 on food surfaces and packages. These results indicated that respiratory viruses may transfer from food surfaces to the hands and subsequently to the mouth, nose or eyes.
    keywords: coronavirus; cov-2; covid-19; et al; food; sars; surfaces; transmission; virus
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        item: #7458 of 7819
          id: cord-351722-3mw1te94
      author: Recalde, M.
       title: Characteristics and outcomes of 627 044 COVID-19 patients with and without obesity in the United States, Spain, and the United Kingdom
        date: 2020-09-03
       words: 5301
      flesch: 47
     summary: Among obese COVID-19 patients, fatality was higher than among obese influenza patients (range: 0·1% to 3%). Although obese COVID-19 patients were younger and less likely to have comorbidities than obese influenza patients in the hospitalized cohorts, they more frequently had adverse outcomes.
    keywords: comorbidities; covid-19; influenza; medrxiv; obese; obesity; patients; preprint
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        item: #7459 of 7819
          id: cord-351734-wjvhu1qg
      author: Kassaw, Chalachew
       title: The Current Mental Health Crisis of COVID-19 Pandemic Among Communities Living in Gedeo Zone Dilla, SNNP, Ethiopia, April 2020
        date: 2020-08-25
       words: 1844
      flesch: 59
     summary: Mental health services have been working to address the crisis through online, outpatient, and inpatient mental health services for all of the communities in need [8] . Therefore, the purpose of this study was to determine the magnitude of mental health crisis and associated factors related to the pandemic.
    keywords: covid-19; crisis; health; pandemic; study
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        item: #7460 of 7819
          id: cord-351735-x1lng449
      author: Flikweert, Antine W.
       title: Late histopathologic characteristics of critically ill COVID-19 patients: Different phenotypes without evidence of invasive aspergillosis, a case series
        date: 2020-07-08
       words: 2685
      flesch: 34
     summary: Often an atypical high compliance phenotype (L-type) is observed during mechanical ventilation in COVID-19 patients in contrast to mechanical ventilation characteristics typically seen in ARDS with low lung compliance phenotype (H -type). The cumulative incidence of venous thromboembolism reported was 49% in COVID-19 patients admitted to the ICU.
    keywords: aspergillosis; case; covid-19; icu; organizing; patients; pneumonia
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        item: #7461 of 7819
          id: cord-351740-779g8tr1
      author: Khaba, Moshawa Calvin
       title: COVID-19 in an HIV-infected patient. Lessons learned from an autopsy case
        date: 2020-09-25
       words: 1830
      flesch: 51
     summary: J o u r n a l P r e -p r o o f Articles Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy : a two-centre descriptive study Clinical Characteristics and Outcomes in People Living With Human Immunodeficiency Virus Hospitalized for Coronavirus Disease Articles Pulmonary and cardiac pathology in African American patients with COVID-19 : an autopsy series from New Orleans Articles Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State : a case series Hematologic parameters in patients with COVID-19 infection Clinical features and outcomes of HIV patients with coronavirus disease 2019 COVID -19 in people living with human immunodeficiency virus : a case series of 33 patients Outcomes Among HIV-Positive Patients Hospitalized With COVID-19 The final cause of death was SARS-CoV-2 (COVID-19) infection in HIV infected patient.
    keywords: cov-2; covid-19; hiv; infection; patients; sars
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        item: #7462 of 7819
          id: cord-351762-n95ar9ci
      author: Wang, Brian Xiangzhi
       title: Susceptibility and prognosis of COVID-19 patients with cardiovascular disease
        date: 2020-06-25
       words: 1497
      flesch: 42
     summary: Importantly, this study also supported the notion that patients with CVDs were more likely to suffer severe illnesses from COVID-19 infection-10.5% of patients with CVDs and 6.0% with hypertension died, compared with the 0.9% in patients with no comorbidities. key: cord-351762-n95ar9ci authors: Wang, Brian Xiangzhi title: Susceptibility and prognosis of COVID-19 patients with cardiovascular disease date: 2020-06-25 journal:
    keywords: covid-19; disease; patients; study
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        item: #7463 of 7819
          id: cord-351770-cirq6pfx
      author: Chen, Wei
       title: SARS-CoV-2 neutralizing antibody levels are correlated with severity of COVID-19 pneumonia
        date: 2020-08-13
       words: 3777
      flesch: 48
     summary: Recently, studies did suggest that COVID-19 patients with moderate-to-severe illness could benefit from corticosteroid-treatment [25, 26] . Compared with the patients who had lower NAb titers, patients with higher NAb titers were older, and had more advanced illness, as reflected by higher LDH and CRP levels, and more extensive lung abnormalities at the time of admission (p＜0.05).
    keywords: antibody; cov-2; covid-19; nab; patients; sars; study; time; titers
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        item: #7464 of 7819
          id: cord-351776-otx5qwyu
      author: Ibáñez-Samaniego, Luis
       title: Elevation of Liver Fibrosis Index FIB-4 Is Associated With Poor Clinical Outcomes in Patients With COVID-19
        date: 2020-06-21
       words: 3897
      flesch: 41
     summary: FIB-4 ≥2.67 defined patients with risk for advanced liver fibrosis. Advanced liver fibrosis is the main determinant of progression to cirrhosis, liver failure, and hepatocellular carcinoma
    keywords: ast; covid-19; disease; fibrosis; liver; patients; risk; study
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        item: #7465 of 7819
          id: cord-351818-znv51wx9
      author: Ge, Q.
       title: Recurrent Neural Reinforcement Learning for Counterfactual Evaluation of Public Health Interventions on the Spread of Covid-19 in the world
        date: 2020-07-10
       words: 4946
      flesch: 50
     summary: As the Covid-19 pandemic soars around the world, there is urgent need to forecast the expected number of cases worldwide and the length of the pandemic before receding and implement public health interventions for significantly stopping the spread of Covid-19. However, implementing public health interventions will cause substantial economic losses and social damage.
    keywords: covid-19; holder; july; license; medrxiv preprint; perpetuity; preprint; version
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        item: #7466 of 7819
          id: cord-351819-ovpz36e7
      author: Beyrouti, Rahma
       title: Characteristics of ischaemic stroke associated with COVID-19
        date: 2020-04-30
       words: 1477
      flesch: 39
     summary: In five of six patients, ischaemic stroke occurred 8-24 days after Covid-19 symptom onset, and in one patient during the presymptomatic phase, suggesting that COVID-19 associated ischaemic stroke is usually delayed, but can occur both early and later in the course of the disease. Screening for aPL might be reasonable in patients with COVID-19 associated ischaemic stroke, although their pathogenic relevance remains uncertain.
    keywords: covid-19; dimer; patients; stroke
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        item: #7467 of 7819
          id: cord-351823-ldbscq4s
      author: Leung, Marco Shiu Tsun
       title: COVID‐19 and Oncology: Service transformation during pandemic
        date: 2020-08-18
       words: 5555
      flesch: 46
     summary: 29 Clinical characteristics in cancer patients with COVID-19 do not differ to the non-cancer population and includes the following and summarized in Table 3 . 2 T A B L E Early data from Wuhan, China in an analysis of 105 patients whose outcomes were matched with 536 control patients showed that in the cancer population, Lung cancer was the most frequent malignancy followed by gastrointestinal, breast, or thyroid, then hematological malignancy; compared with the noncancer control population, cancer patients had higher death rates, ICU admission rates, a greater likelihood of severe symptoms and a doubled chance of requiring invasive mechanical ventilation; however, cancer patients also were more often smokers and experienced more in-hospital infections, which may have been contributing factors to the statistical differences.
    keywords: cancer; care; coronavirus; covid-19; health; nhs; oncology; pandemic; patients; services; treatment
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        item: #7468 of 7819
          id: cord-351825-fdog73g2
      author: Tsai, Cheng-Yu
       title: A Novel Non-contact Self-Injection-Locked Radar for Vital Sign Sensing and Body Movement Monitoring in COVID-19 Isolation Ward
        date: 2020-08-26
       words: 1527
      flesch: 54
     summary: Therefore we attempted to share the experience and try to apply this equipment in COVID-19 patients in future to offer the more reliable and safe policy. This instrument has been used on COVID-19 patients as an auxiliary monitor system in the isolation ward.
    keywords: covid-19; patient; radar; rate
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        item: #7469 of 7819
          id: cord-351845-bli3qm8w
      author: Prasad, Kartikay
       title: Targeting hub genes and pathways of innate immune response in COVID-19: A network biology perspective
        date: 2020-06-26
       words: 4631
      flesch: 38
     summary: Network topology analyses identified 15 high-value targets of SARS CoV-2, which belongs to a subset of canonical ISGs. An Integrative Modeling Approach for Effective Drug Repurposing SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems 0: a major update to the DrugBank database for The comparative toxicogenomics database: update SARS-CoV-2 Launches a Unique Transcriptional Signature from in Vitro, Ex Vivo, and in Vivo Systems Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists Cytoscape: a software environment for integrated models of biomolecular interaction networks STITCH: interaction networks of chemicals and proteins Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources The SARS-coronavirus-host interactome: identification of cyclophilins as target for pancoronavirus inhibitors A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection Network-Guided Discovery of Influenza Virus Replication Host Factors Common Nodes of Virus-Host Interaction Revealed Through an Integrated Network Analysis A cellular census of human lungs identifies novel cell states in health and in asthma A single-cell atlas of the human healthy airways SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes SARS-CoV-2 Receptor ACE2 Is an Interferon Enrichr: a comprehensive gene set enrichment analysis web server 2016 update Interferon-stimulated genes: a complex web of host defenses Emerging roles of interferon-stimulated genes in the innate immune response to hepatitis C virus infection Interferon-inducible protein Mx1 inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly Host genetics of severe influenza: from mouse Mx1 to human IRF7 Hepatitis E virus polymerase binds to IFIT1 to protect the viral RNA from IFIT1-mediated translation inhibition Polymorphisms of interferon-inducible genes OAS-1 and MxA associated with SARS in the Vietnamese population Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication Differential regulation of the OASL and OAS1 genes in response to viral infections Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species ISG15: It's Complicated Consecutive Inhibition of ISG15 Expression and ISGylation by Cytomegalovirus Regulators Innate antiviral response targets HIV-1 release by the induction of ubiquitin-like protein ISG15 ISG15 facilitates cellular antiviral response to dengue and west nile virus infection in vitro Antiviral activity of ISG15 against classical swine fever virus replication in porcine alveolar macrophages via inhibition of autophagy by ISGylating BECN1 MERS-CoV papain-like protease has deISGylating and deubiquitinating activities Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease Targeting poly(I:C) to the TLR3-independent pathway boosts effector CD8 T cell differentiation through IFN-alpha/beta Intranasal treatment with poly(I*C) protects aged mice from lethal respiratory virus infections Prophylactic and therapeutic intranasal administration with an immunomodulator, Hiltonol((R))
    keywords: analysis; cov-2; covid-19; drug; genes; immune; infection; interaction; network; response; sars; virus
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        item: #7470 of 7819
          id: cord-351885-hjw1940x
      author: Zhang, S. X.
       title: First study on mental distress in Brazil during the COVID-19 crisis
        date: 2020-04-23
       words: 2725
      flesch: 59
     summary: key: cord-351885-hjw1940x authors: Zhang, S. X.; Wang, Y.; Afshar Jahanshahi, A.; Jia, J.; Haensel Schmitt, V. G. title: First study on mental distress in Brazil during the COVID-19 crisis date: 2020-04-23 journal: nan DOI: 10.1101/2020.04.18.20070896 sha: doc_id: 351885 cord_uid: hjw1940x Objective: We aim to provide the first evidence of mental distress and its associated predictors among adults in the ongoing COVID-19 crisis in Brazil. This paper aims to provide the first evidence of mental distress and its predictors among adults in Brazil during the COVID-19 crisis.
    keywords: brazil; covid-19; license; preprint
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        item: #7471 of 7819
          id: cord-351890-b33zj9e9
      author: Lahmer, T.
       title: Invasive pulmonary aspergillosis in critically ill patients with severe COVID-19 pneumonia: results from the prospective AspCOVID-19 study
        date: 2020-07-22
       words: 3257
      flesch: 30
     summary: key: cord-351890-b33zj9e9 authors: Lahmer, T. title: Invasive pulmonary aspergillosis in critically ill patients with severe COVID-19 pneumonia: results from the prospective AspCOVID-19 study date: 2020-07-22 journal: nan DOI: 10.1101/2020.07.21.20158972 sha: doc_id: 351890 cord_uid: b33zj9e9 Background: Superinfections, including invasive pulmonary aspergillosis (IPA), are well-known complications of critically ill patients with severe viral pneumonia. The independent association of COVID-19 and invasive pulmonary aspergillosis combined with a high mortality rate implicates that standardized screening for COVID-19 associated invasive pulmonary aspergillosis can help to identify patients at risk at an early stage and initiate antimycotic therapy.
    keywords: aspergillosis; cohort; covid-19; data; ipa; patients; pneumonia; study
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        item: #7472 of 7819
          id: cord-351896-j6h02ab5
      author: Ghannam, Malik
       title: Neurological involvement of coronavirus disease 2019: a systematic review
        date: 2020-06-19
       words: 5067
      flesch: 30
     summary: Cytokine and anticytokine interventions Pathogenic priming likely contributes to serious and critical illness and mortality in COVID-19 via autoimmunity Cytokine release syndrome in COVID-19 patients, a new scenario for an old concern: the fragile balance between infections and autoimmunity Guillain-Barré Syndrome Is COVID-19 a proteiform disease inducing also molecular mimicry phenomena? Steroid-responsive encephalitis in Covid-19 disease Immune thrombocytopenic purpura in a patient with Covid-19 Autoimmune haemolytic anaemia associated with COVID-19 infection The genetic sequence, origin, and diagnosis of SARS-CoV-2 Multiple organ infection and the pathogenesis of SARS Detection of severe acute respiratory syndrome coronavirus in the brain: potential role of the chemokine mig in pathogenesis The role of cytokines including interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease Dysregulation of immune response in patients with COVID-19 in Wuhan, China The COVID-19 pandemic: consideration for brain infection Isolated sudden onset anosmia in COVID-19 infection. D-dimers might play a major prothrombotic role in COVID-19 patients.
    keywords: acute; coronavirus; covid-19; infection; n =; patients; review; sars; stroke; syndrome
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        item: #7473 of 7819
          id: cord-351917-0lcjskjf
      author: Li, S.
       title: Modifiable lifestyle factors and severe COVID-19 risk: Evidence from Mendelian randomization analysis
        date: 2020-10-21
       words: 2173
      flesch: 38
     summary: key: cord-351917-0lcjskjf authors: Li, S. title: Modifiable lifestyle factors and severe COVID-19 risk: Evidence from Mendelian randomization analysis date: 2020-10-21 journal: nan DOI: 10.1101/2020.10.19.20215525 sha: doc_id: 351917 cord_uid: 0lcjskjf Background Lifestyle factors including obesity and smoking are suggested to be related to increased risk of COVID-19 severe illness or related death. However, little is known about whether these relationships are causal, or the relationships between COVID-19 severe illness and other lifestyle factors, such as alcohol consumption and physical activity.
    keywords: covid-19; illness; medrxiv; preprint; risk
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        item: #7474 of 7819
          id: cord-351918-pu7i1jfe
      author: Baek, Yae Jee
       title: A mathematical model of COVID-19 transmission in a tertiary hospital and assessment of the effects of different intervention strategies
        date: 2020-10-26
       words: 4907
      flesch: 47
     summary: Other studies about hospital outbreaks from infectious diseases were conducted with many different mathematical models: a multiagent model or SEIR transmission model [26] Fig 6 shows the effectiveness of all intervention scenarios and the effectiveness of the detection of infectious patients, 80.7%, is the highest among the control measures.
    keywords: covid-19; hospital; model; number; outbreak; patients; screening; transmission
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        item: #7475 of 7819
          id: cord-351930-puhm3w42
      author: Juan, J.
       title: Effects of Coronavirus Disease 2019 (COVID-19) on Maternal, Perinatal and Neonatal Outcomes: a Systematic Review of 266 Pregnancies
        date: 2020-05-06
       words: 4517
      flesch: 47
     summary: From the case-reports, two maternal deaths among pregnant women with COVID-19 were reported. Conclusions: The clinical characteristics of pregnant women with COVID-19 are similar to those of nonpregnant adults with COVID-19.
    keywords: author; cases; covid-19; medrxiv; neonatal; perpetuity; preprint; review
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        item: #7476 of 7819
          id: cord-351931-i9xenu3r
      author: Ruszkiewicz, Dorota M
       title: Diagnosis of COVID-19 by analysis of breath with gas chromatography-ion mobility spectrometry - a feasibility study
        date: 2020-10-24
       words: 5579
      flesch: 42
     summary: [75%] of total negative cases with a mixture of: viral or bacterial pneumonia, asthma, or heart failure) and three were positive ( The Edinburgh PCA stratification model was compared against a clinical assessment of the ultimate severity of the participants' disease during hospital admission, with COVID-19 patients assessed as having fatal, severe/intubated/ITU care, and mild disease. The Dortmund PCA stratification model had an 90% sensitivity and 80% specificity and an AUROC of 0.91 (95%CI 0.87 to 1) for distinguishing COVID-19 patients from other patients.
    keywords: analysis; breath; covid-19; data; diagnosis; dortmund; edinburgh; ims; participants; patients; studies; study
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        item: #7477 of 7819
          id: cord-351940-cg0bewqb
      author: Ngwira, A.
       title: A snap shot of space and time dynamics of COVID-19 risk in Malawi. An application of spatial temporal model
        date: 2020-09-14
       words: 3532
      flesch: 53
     summary: key: cord-351940-cg0bewqb authors: Ngwira, A.; Kumwenda, F.; Munthali, E.; Nkolokosa, D. title: A snap shot of space and time dynamics of COVID-19 risk in Malawi. The space distribution of COVID-19 risk in Malawi in the given time period, shows the cities and the surrounding areas being at increased risk.
    keywords: cases; covid-19; effect; model; risk; time
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        item: #7478 of 7819
          id: cord-351941-fgtatt40
      author: Ghaffarzadegan, Navid
       title: Simulation‐based estimation of the early spread of COVID‐19 in Iran: actual versus confirmed cases
        date: 2020-07-06
       words: 9177
      flesch: 47
     summary: Note that the unofficial reports for death cases in media are based on unofficial reports from the medical community with limited samples, thus γ is likely below one. Moreover, recent investigative reporting by Financial Times, New York Times, Wall Street Journal, and Economist has used all-cause death data of different countries and cities and estimated that globally, as much as 50% of COVID-19 death cases are missed (Burn-Murdoch et al., 2020) .
    keywords: cases; covid-19; data; death; disease; epidemic; estimates; infected; infection; iran; model; number; official; parameters; rate
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        item: #7479 of 7819
          id: cord-351972-whl0w54u
      author: Lorenzo-Villalba, Noel
       title: Cutaneous Complications Secondary to Haemostasis Abnormalities in COVID-19 Infection
        date: 2020-06-12
       words: 1123
      flesch: 36
     summary: Anticoagulation therapy and the presence of lupus anticoagulant may induce cutaneous complications during COVID-19 infection. There is currently little information about the prevalence and nature of dermatological manifestations related to COVID-19 infection.
    keywords: anticoagulation; covid-19; infection; patient
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        item: #7480 of 7819
          id: cord-352030-hnm54k4r
      author: Liu, Jie
       title: Epidemiological, Clinical Characteristics and Outcome of Medical Staff Infected with COVID-19 in Wuhan, China: A Retrospective Case Series Analysis
        date: 2020-03-13
       words: 5267
      flesch: 47
     summary: The exact mode of medical staff infection remains unclear. Findings The median age of medical staff included was 35 years old.
    keywords: coronavirus; covid-19; group; license; medical; patients; preprint; sars; staff
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        item: #7481 of 7819
          id: cord-352065-960xqft4
      author: Rello, Jordi
       title: Update in COVID-19 in the Intensive Care Unit from the 2020 HELLENIC Athens International Symposium
        date: 2020-10-22
       words: 4979
      flesch: 32
     summary: Regarding detection and diagnosis, studies have used machine learning algorithms to predict the criticality of COVID-19 positive patients using clinical features and identifying which of them have statistically significant hazard errors [64, 65] . COVID-19 infection has shown a great variability in terms of mortality in different regions around the globe.
    keywords: coronavirus; cov-2; covid-19; disease; icu; infection; lung; pandemic; patients; phenotype; pneumonia; sars
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        item: #7482 of 7819
          id: cord-352096-cc3dzycl
      author: Richman, Douglas D.
       title: Antiviral Drug Discovery To Address the COVID-19 Pandemic
        date: 2020-09-25
       words: 1522
      flesch: 27
     summary: The magnitude of the morbidity and mortality inflicted upon the global population in less than 1 year has driven the inescapable conclusion that the discovery and development of effective antiviral drugs for COVID-19 are urgent and should be prioritized. These studies were conducted in subjects with moderate to severe disease, while efficacy with antiviral drugs generally is greatest when administered early in disease.
    keywords: activity; cov-2; covid-19; drugs; sars
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        item: #7483 of 7819
          id: cord-352102-ssk24jkx
      author: Suwanwongse, Kulachanya
       title: Successful Conservative Management of Acute Appendicitis in a Coronavirus Disease 2019 (COVID-19) Patient
        date: 2020-04-26
       words: 1127
      flesch: 30
     summary: Our case report illustrates the implementation of successful conservative treatment for acute appendicitis in COVID-19 patients. To date, there is no report regarding the outcomes of non-operative treatment for acute appendicitis in COVID-19 patients.
    keywords: appendicitis; covid-19; patients
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        item: #7484 of 7819
          id: cord-352122-u9pv2x2j
      author: Yang, Xiao
       title: Social support and clinical improvement in COVID-19 positive patients in China
        date: 2020-08-24
       words: 3633
      flesch: 44
     summary: Social support related factors for linear regression included age, gender, marital status, education level, number of family members infected, any close relatives or friends who died in the pandemic, severity of pneumonia, and score of social support rating scale (SSRS). Social support related factors for linear regression included age, gender, marital status, education level, number of family members infected, any close relatives or friends who died in the pandemic, severity of pneumonia, nucleic acid test at Stage 2, and score of social support rating scale (SSRS) at Stage 2.
    keywords: covid-19; factors; health; patients; sleep; social; support
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        item: #7485 of 7819
          id: cord-352123-0bflqj1c
      author: Csiszar, Anna
       title: Companion animals likely do not spread COVID-19 but may get infected themselves
        date: 2020-08-07
       words: 4758
      flesch: 46
     summary: Prior to the news of the Bronx Zoo big cat cases, there have not been any reports of pets or other animals in the USA contracting COVID-19, according to the websites of the US Department of Agriculture and the Centers for Disease Control and Prevention (CDC) The CDC recently issued an interim guidance for public health professionals managing the home care and isolation of people with COVID-19 who have pets or other animals (including service or working animals) in the same home
    keywords: age; animals; cats; cov-2; covid-19; disease; dogs; sars; virus; years
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        item: #7486 of 7819
          id: cord-352141-y3s8li0v
      author: Bouchoucha, Stéphane
       title: Family‐centred care during a pandemic: The hidden impact of restricting family visits
        date: 2020-06-13
       words: 1334
      flesch: 33
     summary: Another aspect to consider is the potential impact that having to restrict family visits could have on nurses. Restricting family visits, while a necessary measure to decrease the spread of COVID-19 to vulnerable patients and the community, is likely to have negative effects on families and nurses alike and these impacts need to be carefully considered.
    keywords: care; family; nurses; patients
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        item: #7487 of 7819
          id: cord-352152-d3owtd98
      author: Wang, Cuiyan
       title: Immediate Psychological Responses and Associated Factors during the Initial Stage of the 2019 Coronavirus Disease (COVID-19) Epidemic among the General Population in China
        date: 2020-03-06
       words: 6507
      flesch: 41
     summary: Most respondents spent 20–24 h per day at home (84.7%); were worried about their family members contracting COVID-19 (75.2%); and were satisfied with the amount of health information available (75.1%). Knowledge about COVID-19 variables included knowledge about the routes of transmission, level of confidence in diagnosis, level of satisfaction of health information about COVID-19, the trend of new cases and death, and potential treatment for COVID-19 infection.
    keywords: anxiety; covid-19; depression; epidemic; health; impact; information; outbreak; respondents; stress
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        item: #7488 of 7819
          id: cord-352156-sa8cvyuw
      author: Lindeman, Robbert-Jan
       title: Preventing spread of SARS-CoV-2 and preparing for the COVID-19 outbreak in the surgical department: perspectives from two Scandinavian countries
        date: 2020-05-06
       words: 1840
      flesch: 38
     summary: Several initiatives such as the organization of a global cohort capturing real-world data concerning the management of surgical COVID-19 patients (COVIDSurg cohort study [9] ) and the construction of a structured evidence-based global guideline for orthopedic management has now been established [12] . Despite the initial different approaches to social distancing, with aims of mitigation or suppression of the outbreak, the common primary goal has been to 'flatten the curve' to make it possible for hospitals to accommodate the influx of COVID-19 patients.
    keywords: covid-19; norway; patients; sars; surgery
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        item: #7489 of 7819
          id: cord-352159-qx16i7s1
      author: Pettit, Natasha N.
       title: Late Onset Infectious Complications and Safety of Tocilizumab in the Management of COVID‐19
        date: 2020-08-13
       words: 3331
      flesch: 44
     summary: We sought to evaluate the incidence of these potential complications following the use of TCZ among COVID-19 patients. TCZ use was avoided in patients with confirmed or suspected bacterial infections, neutropenia, thrombocytopenia, or if liver function tests (LFTs) were > 10x upper limit of normal.
    keywords: control; covid-19; dose; group; infections; patients; tcz
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        item: #7490 of 7819
          id: cord-352187-h9if17ba
      author: Aksoy, Yasemin Erkal
       title: Psychological effects of nurses and midwives due to COVID-19 outbreak: The case of Turkey
        date: 2020-07-08
       words: 2563
      flesch: 50
     summary: While social media researches have difficulties for users not to have organic (real) accounts, it is easy to access major data when it is difficult to collect face-toface data such as COVID-19 outbreak. Uncertainties about the vaccine, treatment and transmission rate of COVID-19 virus can affect the level of anxiety of nurses and midwives (Geçgin & Sahranç, 2017) .
    keywords: anxiety; covid-19; midwives; nurses; uncertainty
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        item: #7491 of 7819
          id: cord-352193-izzqdg3v
      author: Allen, M.
       title: Organising outpatient dialysis services during the COVID-19 pandemic. A simulation and mathematical modelling study.
        date: 2020-04-27
       words: 4281
      flesch: 52
     summary: Results If current outpatient capacity is maintained there is sufficient capacity in the South of England to keep COVID-19 negative/recovered and positive patients in separate sessions, but rapid reallocation of patients may be needed (as sessions are cleared of negative/recovered patients to enable that session to be dedicated to positive patients). If current outpatient capacity is maintained there is sufficient capacity in the South of England to keep COVID-19 negative/recovered and positive patients in separate sessions, but rapid reallocation of patients may be needed (as sessions are cleared of negative/recovered patients to enable that session to be dedicated to positive patients).
    keywords: capacity; covid; covid-19; dialysis; model; patients; time; transport
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        item: #7492 of 7819
          id: cord-352215-dhkvh45t
      author: Ramachandran, Preethi
       title: Increased serum aminotransferase activity and clinical outcomes in Coronavirus disease 2019
        date: 2020-06-30
       words: 2544
      flesch: 40
     summary: [AST]/alanine aminotransferase [ALT]) is commonly noted among COVID-19 patients. We retrospectively evaluated hospitalized COVID-19 patients with clinically significant elevated aminotransferases (defined as >2 times upper limit of normal) and compared them with COVID-19 patients without an elevation in aminotransferases.
    keywords: aminotransferases; covid-19; disease; liver; patients; study
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        item: #7493 of 7819
          id: cord-352247-baqbxez9
      author: Kobayashi, Yoshiharu
       title: Public Support for Development Aid during the COVID-19 Pandemic
        date: 2020-10-21
       words: 9125
      flesch: 51
     summary: The results demonstrate that messages that convey anticipated detrimental health consequences in developing countries barely move aid support. In contrast, messages emphasizing that helping African countries in order to weaken the next wave of the pandemic at home generate a sizable increase in aid support.
    keywords: aid; aid support; countries; country; covid-19; development; donor; financial; health; household; pandemic; public; results; support; worries
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        item: #7494 of 7819
          id: cord-352256-qxdakdk0
      author: Yousefi, Bahman
       title: A global treatments for coronaviruses including COVID‐19
        date: 2020-05-11
       words: 4045
      flesch: 31
     summary: A retrospective cohort study New insights on the antiviral effects of chloroquine against coronavirus: What to expect for COVID-19? Mycophenolic acid inhibits dengue virus infection by preventing replication of viral RNA Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques Effectiveness of favipiravir (T-705) against wildtype and oseltamivir-resistant influenza B virus in mice Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor Mechanisms of action of ribavirin against distinct viruses Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. Neuraminidase inhibitors such as oseltamivir, peramivir, and zanamivir are invalid for 2019‐nCoV and are not recommended for treatment but protease inhibitors such as lopinavir/ritonavir (LPV/r) inhibit the progression of MERS‐CoV disease and can be useful for patients of COVID‐19 and, in combination with Arbidol, has a direct antiviral effect on early replication of SARS‐CoV. Ribavirin reduces hemoglobin concentrations in respiratory patients, and remdesivir improves respiratory symptoms.
    keywords: ace2; coronavirus; cov; ncov; patients; receptor; ribavirin; sars; treatment
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        item: #7495 of 7819
          id: cord-352272-9zg8q0gk
      author: Zhang, Jiancheng
       title: Poor-sleep is associated with slow recovery from lymphopenia and an increased need for ICU care in hospitalized patients with COVID-19: A retrospective cohort study
        date: 2020-06-06
       words: 3688
      flesch: 38
     summary: However, the effects of sleep quality during hospitalization for COVID-19 remain unclear. This retrospective, single-center cohort study was conducted to investigate the effects of sleep quality on recovery from lymphopenia and clinical outcomes in hospitalized patients with laboratory-confirmed COVID-19 admitted to the West District of Wuhan Union Hospital between January 25 and March 15, 2020.
    keywords: covid-19; et al; group; hospital; patients; quality; sleep
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        item: #7496 of 7819
          id: cord-352288-zr96k6p1
      author: Zou, Fengwei
       title: Cardiac Injury and COVID-19: A Systematic Review and Meta-Analysis
        date: 2020-06-23
       words: 1573
      flesch: 40
     summary: If mortality in patients with or without 90 cardiac injury was not directly reported, the mortality rate of patients with cardiac injury was 91 calculated as the ratio of deceased patients with cardiac injury to the overall number of patients 92 with reported cardiac injury. We searched PubMed and Embase for studies that evaluated cardiac injury in hospitalized COVID-19 patients.
    keywords: cardiac; injury; patients
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        item: #7497 of 7819
          id: cord-352293-ha7xts89
      author: Thakur, Aditya
       title: Mental Health in High School Students at the Time of COVID-19: A Student’s Perspective
        date: 2020-08-26
       words: 1203
      flesch: 49
     summary: • Leverage digital technology for mental health support: HSS can access digital options for support and resources by exploring online portals that offer resource hubs and self-assessment tools. Self-help apps, digital counseling and telemedicine services will continue to allow increased access to mental health services from home. Child and adolescent psychiatry and mental health Social Media Use During Social Distancing.
    keywords: covid-19; health; pandemic
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        item: #7498 of 7819
          id: cord-352302-are8vvhh
      author: Hartman, W.
       title: Hospitalized COVID-19 patients treated with Convalescent Plasma in a mid-size city in the midwest
        date: 2020-06-22
       words: 3139
      flesch: 50
     summary: Methods Hospitalized COVID-19 patients categorized as having Severe or Life-Threatening disease according to the Mayo Clinic Emergency Access Protocol were screened, consented, and treated with convalescent plasma collected from local donors recovered from COVID-19 infection. While larger cities like New York City and Seattle were experiencing large surges in the volume of critically ill patients in their health systems, the health care system in Madison saw relatively modest numbers of COVID-19 patients.
    keywords: covid-19; disease; life; patients; plasma; preprint
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        item: #7499 of 7819
          id: cord-352304-tt2q5mgs
      author: Sun, Dan
       title: Clinical features of severe pediatric patients with coronavirus disease 2019 in Wuhan: a single center’s observational study
        date: 2020-03-19
       words: 3241
      flesch: 48
     summary: On entering the outbreak stage and improvement of pathogen detection, pediatric patients (even newborns) have been reported increasingly Children have special immune response system which is distinct from adults [19] ; therefore, pediatric patients with COVID-19 have their own clinical features and therapeutic responses [20] .
    keywords: coronavirus; covid-19; disease; february; patients; sars; wuhan
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        item: #7500 of 7819
          id: cord-352324-tle14vtm
      author: Martini, Chiara
       title: Phase 3 of COVID-19: treat your patients and care for your radiographers. A designed projection for an aware and innovative radiology department.
        date: 2020-10-23
       words: 2548
      flesch: 43
     summary: An operational infection prevention and a control programme to minimize the risk of transmission of healthcare-associated infections to patients, hospital staff and visitors; • An efficient and accurate triage system and a management strategy to ensure adequate treatment of Covid-19 patients; • The ability of HCWs to recognize and immediately report suspected cases as the cornerstone of hospital-based Covid-19 surveillance. A setting envisaging two radiographers is highly recommended when managing Covid-19 patients.
    keywords: care; covid-19; patients; radiographer; radiology
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        item: #7501 of 7819
          id: cord-352329-dq69zlpn
      author: Gastélum-Cano, José María
       title: Higher values of fasting blood glucose and glycated hemoglobin are not associated with mortality in Covid-19 Mexican patients
        date: 2020-11-05
       words: 753
      flesch: 49
     summary: Recently, abnormal fasting blood glucose (FBG) levels have been associated with increased death risk in Covid-19 patients. A retrospective analysis of clinical and laboratory data obtained from Covid-19 patients at admission to intensive care services in the IMSS Hospital in Celaya, from August 13 to September 02, 2020.
    keywords: covid-19; diabetes; patients
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        item: #7502 of 7819
          id: cord-352332-c6phkk8r
      author: Al-Benna, Sammy
       title: Sword of Damocles: application of the ethical principles of resource allocation to essential cancer surgery patients requiring beds in limited supply during the COVID-19 pandemic
        date: 2020-08-07
       words: 743
      flesch: 39
     summary: key: cord-352332-c6phkk8r authors: Al-Benna, Sammy title: Sword of Damocles: application of the ethical principles of resource allocation to essential cancer surgery patients requiring beds in limited supply during the COVID-19 pandemic date: 2020-08-07 journal: Eur Surg DOI: 10.1007/s10353-020-00655-y sha: doc_id: 352332 cord_uid: c6phkk8r nan Surgery is the oldest modality of cancer therapy and still forms the mainstay of treatment for solid tumours Essential cancer surgery has been restricted to a minimum reasonable allotment in accordance with national and international guidelines and regulations during the COVID-19 pandemic, rather than to higher volumes.
    keywords: covid-19; surgery
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        item: #7503 of 7819
          id: cord-352341-dhc748pn
      author: Miranda-Zazueta, G.
       title: Manejo farmacológico de pacientes con enfermedades hepáticas y pancreáticas que involucran terapias inmunosupresoras. Posicionamiento en el marco de la pandemia de SARS-COV-2 (COVID-19)
        date: 2020-06-17
       words: 4120
      flesch: 37
     summary: La atención de la mayoría de los pacientes y el ajuste de tratamiento se ha realizado vía telefónica o mediante En el caso de la inducción de la remisión, habrá que seleccionar y diferenciar adecuadamente a los pacientes con necesidad de tratamiento urgente (ictericia obstructiva, dolor abdominal) de aquellos con J o u r n a l P r e -p
    keywords: casos; con; cov-2; covid-19; del; dosis; enfermedad; este; hepático; infección; inmunosupresión; las; los; mayor; pacientes; para; por; puede; que; riesgo; sars; sin; trasplante; tratamiento
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        item: #7504 of 7819
          id: cord-352365-b9cmviny
      author: Marchetti, Monia
       title: COVID-19-driven endothelial damage: complement, HIF-1, and ABL2 are potential pathways of damage and targets for cure
        date: 2020-06-24
       words: 3899
      flesch: 26
     summary: [9, 10] , while both C3a and C5a increase endothelial permeability and activate endothelial cells, thereby increasing the expression of adhesion molecules and cytokines [11, 12] , and the distal complement activation product C5 b-9 triggers intracellular fluxes of calcium in epithelial and endothelial cells. This downregulation enhances C3a release and caspase 3 deposition onto endothelial cells [13] .
    keywords: ards; c5a; cells; complement; covid-19; damage; endothelial; imatinib; injury; lung; patients; sars
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        item: #7505 of 7819
          id: cord-352382-mazwgsbc
      author: Vavassori, Andrea
       title: Practical indications for management of patients candidate to Interventional and Intraoperative Radiotherapy (Brachytherapy, IORT) during COVID-19 pandemic – A document endorsed by AIRO (Italian Association of Radiotherapy and Clinical Oncology) Interventional Radiotherapy Working Group
        date: 2020-05-08
       words: 1446
      flesch: 11
     summary: Follow-up evaluations should be: -postponed until proven healing in COVID-19 positive patients, -postponed and/or converted to telephone contact in case of negative COVID-19 patients without referred post-treatment symptoms, -planned according to the clinical case presentation verified by telephone contact, in COVID-19 negative patients but with referred symptoms related to radiation treatments. 9 Table 2 summarizes relevant clinical suggestions for COVID-19 negative or positive patients eligible for IRT treatments in relation to oncological disease.
    keywords: covid-19; patients; radiation; radiotherapy; treatment
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        item: #7506 of 7819
          id: cord-352401-tmt1pmw9
      author: Curatola, Antonietta
       title: Use of Handheld Transceiver for Hospital Healthcare Workers-Caregiver Communication During the Coronavirus disease 2019 (COVID-19) Outbreak in Pediatric Emergency Department
        date: 2020-04-13
       words: 992
      flesch: 50
     summary: 4 Our hospital tried to adapt to COVID-19 health emergency in a short time. The transmission of the 2019-nCov infection happened through the respiratory droplets by infected patients, but coronavirus can also be transmitted by contact with contaminated objects, such as phones, toys and doorknobs 3 ; however, also asymptomatic cases play a critical role in the transmission process.
    keywords: cases; coronavirus; covid-19
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        item: #7507 of 7819
          id: cord-352460-ql0eogzz
      author: Farmer, Nicole
       title: COVID-19: Growing Health Disparity Gaps and an Opportunity for Health Behavior Discovery?
        date: 2020-07-10
       words: 2549
      flesch: 21
     summary: As already stated, a key consideration within the pandemic is the role of health behaviors and how they impact psychosocial health. Most importantly, once the COVID-19 social restrictions are lifted, will this health-promoting behavior be maintained or cease, and what are the significant social determinants of such actions? Identifying the role of COVID-19 on health behaviors could be especially important for certain populations that are affected by health disparities, such as African Americans.
    keywords: african; behaviors; covid-19; health; pandemic; psychosocial
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        item: #7508 of 7819
          id: cord-352475-cmmpy5u7
      author: Pemmada, Rakesh
       title: Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics
        date: 2020-09-11
       words: 7777
      flesch: 34
     summary: Members of antiviral coatings have been divided into three major groups (antiviral polymers, metal ions/metal oxides, and functional nanomaterials), based on the type of materials used at the contaminated sites. A material with superior water repelling properties is preferred for antiviral coatings.
    keywords: activity; antiviral; coating; copper; influenza; ions; materials; metal; nanoparticles; oxides; polymers; surface; viricidal; viruses
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        item: #7509 of 7819
          id: cord-352512-h58oh2jx
      author: Korbel, Jan O.
       title: Effects of the COVID-19 pandemic on life scientists
        date: 2020-05-11
       words: 1655
      flesch: 39
     summary: Our survey confirmed that, overall, there has been a significant impact of institute closures on life scientists: 57% of life scientists reported that they had lost some of their work. At the same time, levels of self-perceived productivity dropped, where dry lab scientists were much more likely to continue carrying out their work from home as expected (29% of dry lab scientists, but only 10% of wet lab scientists, reported at least 80% productivity).
    keywords: covid-19; lab; life; scientists; work
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        item: #7510 of 7819
          id: cord-352524-g7khma2j
      author: Rennard, Stephen I.
       title: Chicken soup in the time of COVID
        date: 2020-05-06
       words: 1145
      flesch: 51
     summary: Chicken soup, often made by a lengthy and loving process, can provide real psychosocial support. key: cord-352524-g7khma2j authors: Rennard, Stephen I.; Kalil, Andre C.; Casaburi, Richard title: Chicken soup in the time of COVID date: 2020-05-06 journal: Chest DOI: 10.1016/j.chest.2020.04.044 sha: doc_id: 352524 cord_uid: g7khma2j nan The COVID-19 pandemic has led to a variety of behaviors as people try to cope with the very real personal and societal threats and the associated anxieties.
    keywords: chicken; covid-19; soup
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        item: #7511 of 7819
          id: cord-352526-t8odetzw
      author: Pinto, Bruna G G
       title: ACE2 Expression is Increased in the Lungs of Patients with Comorbidities Associated with Severe COVID-19
        date: 2020-06-11
       words: 3033
      flesch: 36
     summary: The fact that ACE2 gene is located in the X chromosome, and the initial findings showing that older males with comorbidities are more likely to be have severe COVID-19 compared to females (1), indicate that ACE2 expression in the lung may be sex-biased. From this analysis, we found that ACE2 expression could be regulated by enzymes that modify histones, including KDM5B. This identification of a common molecular mechanism of increased COVID-19 severity in patients with diverse comorbidities could direct the development of interventions to reduce the infection risk and disease severity in this population.
    keywords: ace2; comorbidities; covid-19; disease; expression; hypertension; lung; patients; pulmonary
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        item: #7512 of 7819
          id: cord-352538-cb3j2y1s
      author: Farrell, Penny
       title: COVID-19 and Pacific food system resilience: opportunities to build a robust response
        date: 2020-07-20
       words: 4786
      flesch: 41
     summary: In this paper, we examine some of the key pathways of impact on food systems, and identify opportunities to strengthen Pacific food systems during these challenging times. Anna has worked on aspects of sustainable food systems, in agriculture and fisheries, for over 20 years and is currently investigating value chains and Pacific food systems.
    keywords: covid-19; food; health; impacts; nutrition; pacific; policy; production; region; research; security; systems; trade
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        item: #7513 of 7819
          id: cord-352543-8il0dh58
      author: Kuzdeuov, A.
       title: A Network-Based Stochastic Epidemic Simulator: Controlling COVID-19 with Region-Specific Policies
        date: 2020-05-06
       words: 6262
      flesch: 41
     summary: We set the number of exposed individuals to ten on this date, as this figure yielded accurate model state populations going forward. Calibration is tuning model parameters with available real epidemic data.
    keywords: covid-19; epidemic; individuals; license; model; node; number; population; preprint; simulator; state; transition
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        item: #7514 of 7819
          id: cord-352544-7b6btzrx
      author: Liu, Zhelong
       title: The association of diabetes and the prognosis of COVID-19 patients: a retrospective study
        date: 2020-08-25
       words: 3293
      flesch: 42
     summary: key: cord-352544-7b6btzrx authors: Liu, Zhelong; Bai, Xi; Han, Xia; Jiang, Wangyan; Qiu, Lin; Chen, Shi; Yu, Xuefeng title: The association of diabetes and the prognosis of COVID-19 patients: a retrospective study date: 2020-08-25 journal: Diabetes Res Clin Pract DOI: 10.1016/j.diabres.2020.108386 sha: doc_id: 352544 cord_uid: 7b6btzrx Abstract Aims This study evaluated the impact of previous glycemic control and in-hospital use of antidiabetic/antihypertensive drugs on the prognosis of COVID-19 patients with diabetes. Data regarding the impact of diabetes on the prognosis of COVID-19 patients are scant and controversial.
    keywords: covid-19; diabetes; hba1c; patients; risk; worsening
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        item: #7515 of 7819
          id: cord-352553-me1tpqss
      author: Sugand, K.
       title: The impact of COVID-19 on acute Trauma and Orthopaedic referrals and surgery in the UK: the "golden peak weeks" of the first national multi-centre observational study. The COVid-Emergency Related Trauma and orthopaedics (COVERT) Collaborative
        date: 2020-08-24
       words: 5726
      flesch: 47
     summary: This was the first national study to assess impact of COVID-19 pandemic on acute Orthopaedic trauma and it will aid clinicians in counselling trauma patients of the increased risk of mortality during the era of COVID-19 as well as acting as a risk-prediction tool influencing policymaking as the pandemic continues with potential subsequent waves. This was the first national study to assess impact of COVID-19 pandemic on acute Orthopaedic trauma and it will aid clinicians in counselling trauma patients of the increased risk of mortality during the era of COVID-19 as well as acting as a risk-prediction tool influencing policymaking as the pandemic continues with potential subsequent waves.
    keywords: covid-19; medrxiv; medrxiv preprint; mortality; patients; perpetuity; preprint; trauma
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        item: #7516 of 7819
          id: cord-352557-l7sahv5t
      author: Takla, Michael
       title: Chloroquine, hydroxychloroquine, and COVID-19: systematic review and narrative synthesis of efficacy and safety
        date: 2020-11-13
       words: 7595
      flesch: 34
     summary: 10% of HCQ patients experienced averse ECG modifications requiring cessation of treatment after a median of 4 days. HCQ patients had lower prevalence of comorbidities, except hepatic cirrhosis.
    keywords: control; covid-19; covid-19 patients; data; day; et al; evidence; hcq; hydroxychloroquine; patients; safety; studies; study; treatment
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        item: #7517 of 7819
          id: cord-352562-qfb478sf
      author: Yamamoto, Lidia
       title: SARS-CoV-2 infections with emphasis on pediatric patients: a narrative review
        date: 2020-09-04
       words: 7323
      flesch: 34
     summary: Xiang et al. 52 tested 126 serum samples from COVID-19 patients, with 57.1% IgM sensitivity, 100% specificity and 69% accuracy. Criteria for releasing COVID-19 patients from isolation SARS and MERS: recent insights into emerging coronaviruses Understanding evolution of SARS-CoV-2: a perspective from analysis of genetic diversity of RdRp gene Emerging genetic diversity among clinical isolates of SARS-CoV-2: lessons for today The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak Real estimates of mortality following COVID-19 infection Epidemiological and clinical characteristics of 26 asymptomatic SARS-CoV-2 carriers SARS-CoV-2 receptor and regulator of the Renin-Angiotensin system: celebrating the 20th anniversary of the discovery of ACE2 Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection in children and adolescents: a systematic review The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak -an update on the status Gastrointestinal manifestations of SARS-CoV-2 infection and virus load in fecal samples from the Hong Kong cohort and systematic review and meta-analysis Kidney involvement in COVID-19 and rationale for extracorporeal therapies Neurologic manifestations of hospitalized patients with coronavirus disease Computed tomographic imaging of 3 patients with Coronavirus disease 2019 pneumonia with negative virus real-time reversetranscription Polymerase Chain Reaction test Nasal gene expression of Angiotensin-converting enzyme 2 in children and adults Ocular manifestations of a hospitalised patient with confirmed 2019 novel coronavirus disease Chilblain-like lesions in children following suspected COVID-19 infection Androgen regulates SARS-CoV-2 receptor levels and is associated with severe COVID-19 symptoms in men Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor COVID-19 infection and circulating ACE2 levels: protective role in women and children Coronavirus infections in children including COVID-19: an overview of the epidemiology, clinical features, diagnosis, treatment and prevention options in children Coronavirus disease 2019 in critically ill children: a narrative review of the literature SARS-COV-2 infection in children and newborns: a systematic review SARS-CoV-2 infection in children COVID-19 in children and adolescents in Europe: a multinational, multicentre cohort study Coinfection of SARS-CoV-2 and multiple respiratory pathogens in children Multisystem inflammatory syndrome in U.S. children and adolescents Multisystem inflammatory syndrome in children in New York State Flash survey on severe acute respiratory syndrome Coronavirus-2 infections in paediatric patients on anticancer treatment e65 SARS-CoV-2 infections with emphasis on pediatric patients: a narrative review How is immunosuppressive status affecting children and adults in SARS-CoV-2 infection?
    keywords: ace2; antibodies; children; cov-2; covid-19; days; disease; infection; patients; pcr; sars; symptoms; syndrome; women
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        item: #7518 of 7819
          id: cord-352579-ndcbmgfj
      author: Takahashi, Takuto
       title: Pharmacogenomics of COVID-19 therapies
        date: 2020-08-18
       words: 5264
      flesch: 28
     summary: In conclusion, although direct evidence in COVID-19 patients is lacking, we identified potential actionable genetic markers in COVID-19 therapies. Clinical studies in COVID-19 patients are deemed warranted to assess potential roles of these markers.
    keywords: azithromycin; covid-19; drug; hydroxychloroquine; lopinavir; patients; pharmacogenomics; ribavirin; risk; tocilizumab; treatment; use; variants
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        item: #7519 of 7819
          id: cord-352580-l6vkzja0
      author: Iltaf, Samar
       title: Frequency of Neurological Presentations of Coronavirus Disease in Patients Presenting to a Tertiary Care Hospital During the 2019 Coronavirus Disease Pandemic
        date: 2020-08-18
       words: 2270
      flesch: 38
     summary: Patients positive for immunoglobulin G antibodies to SARS-CoV-2 were excluded, as were patients with prior neurological or psychiatric diseases, systemic malignancy, hypercoagulability state, intracranial tumors, uncontrolled hypertension or diabetes mellitus, extremes of ages or anemia. A survey on neurological manifestations was specially designed for COVID-19 patients by researchers in the clinical faculty of the neurology department.
    keywords: cov-2; covid-19; manifestations; patients; sars; study
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        item: #7520 of 7819
          id: cord-352607-71986j7i
      author: Cournoyer Lemaire, Elise
       title: Extraordinary times call for extraordinary measures: the use of music to communicate public health recommendations against the spread of COVID-19
        date: 2020-07-22
       words: 1499
      flesch: 21
     summary: Yet, beyond its entertaining property, research shows that there are numerous reasons to turn to music to promote the population's adherence to public health measures. key: cord-352607-71986j7i authors: Cournoyer Lemaire, Elise title: Extraordinary times call for extraordinary measures: the use of music to communicate public health recommendations against the spread of COVID-19 date: 2020-07-22 journal: Can J Public Health DOI: 10.17269/s41997-020-00379-2 sha: doc_id: 352607 cord_uid: 71986j7i To promote the population’s adherence to COVID-19 public health preventive measures, the Quebec (Canada) government solicited the assistance of local music artists.
    keywords: covid-19; health; music; public
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        item: #7521 of 7819
          id: cord-352630-dx1fwngb
      author: Hossain, Md. Sabbir
       title: Impact of weather on COVID-19 transmission in South Asian Countries: an application of the ARIMAX model
        date: 2020-11-02
       words: 3111
      flesch: 41
     summary: We found that maximum wind speed had a significant negative impact on COVID-19 transmission which is in line with some previous studies (Ahmadi et al., 2020; Islam et al., 2020; Zoran et al., 2020) . Rainfall had a significant negative impact on COVID-19 transmission in India and Pakistan, also had positive impact in Pakistan (at lag 12) which is in line with (A. Gupta et al., 2020; Menebo, 2020; Sobral et al., 2020) and opposite with some recently published studies (Ahmadi et al., 2020; Bashir et al., 2020; Tosepu et al., 2020) .
    keywords: cases; covid-19; et al; temperature; transmission
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        item: #7522 of 7819
          id: cord-352640-fycwhyfv
      author: Goel, Ashish
       title: Profile of Patients Suspected to be COVID-19: A Retrospective Analysis of Early Pandemic Data
        date: 2020-08-29
       words: 2758
      flesch: 55
     summary: In a retrospective study by Xiao et al. of 301 confirmed COVID-19 patients hospitalized at Tongji Hospital in Wuhan, China, the median age was 58 years and 51.2% were male [12] . As clinical data is being reported from around the globe, it becomes important to focus on local subjects in a global milieu, lest one misses the trees for the forest.
    keywords: age; analysis; covid-19; data; patients; subjects
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        item: #7523 of 7819
          id: cord-352642-u513wnu1
      author: Patrocínio de Jesus, Rita
       title: Reactivation of SARS-CoV-2 after Asymptomatic Infection while on High-Dose Corticosteroids. Case Report
        date: 2020-10-02
       words: 2218
      flesch: 37
     summary: A recent study which compared IgA, IgM, and IgG responses in COVID-19 patients [10] has showed that medium seroconversion time was 4 to 6 days for IgA and IgM and 5 to 10 days for IgG. Notably, this patient's IgA levels were not available on the first serology sample collected on the seventh day after symptoms onset, which is of importance since IgA detection seems to show the highest sensitivity at the beginning of disease (highest positive diagnostic rate at 4 to 10 days after symptom onset) Fluctuating shedding of SARS-CoV-2 has been described on COVID-19 patients [12, 13] and not only has asymptomatic infection been associated with a higher likelihood of SARS-CoV-2 RNA clearance within the first week of diagnosis when compared with symptomatic infection [14] but there have also been reports of COVID-19 reactivation
    keywords: asymptomatic; cov-2; covid-19; days; patients; sars
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        item: #7524 of 7819
          id: cord-352665-ik67gpxf
      author: González-Rodríguez, Alexandre
       title: Mental health in times of COVID: Thoughts after the state of alarm()
        date: 2020-10-15
       words: 2315
      flesch: 40
     summary: key: cord-352665-ik67gpxf authors: González-Rodríguez, Alexandre; Labad, Javier title: Mental health in times of COVID: Thoughts after the state of alarm() date: 2020-10-15 journal: Med Clin (Engl Ed) DOI: 10.1016/j.medcle.2020.07.007 sha: doc_id: 352665 cord_uid: ik67gpxf nan Coronavirus disease type 2 of the severe acute respiratory syndrome (SARS-CoV-2), also known as COVID-19, was first described in Wuhan, China in December 2019 and has spread rapidly around the world. We herein reflect on aspects related to mental health during the three months of the state of alarm.
    keywords: covid-19; disease; health; mental; pandemic; patients
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        item: #7525 of 7819
          id: cord-352668-qjlqsb2k
      author: Cabello, Francisco
       title: Consensus on Recommendations for Safe Sexual Activity during the COVID-19 Coronavirus Pandemic
        date: 2020-07-20
       words: 4842
      flesch: 37
     summary: Possible pharmaceutical and behavioral approaches Sexual function and depressive symptoms among male North American medical students Intimacy and belonging: The association between sexual activity and depression among older adults Factors associated with sexual health and well being in older adulthood Feeling Good is Good for you: How Pleasure Can Boost Your Immune System and Lengthen Your Life Sex for the mature adult: Health, self-esteem and countering ageist stereotypes Secrets of the Super Young Is good sex good for you? In all other cases (for those under quarantine, those with some clinical symptoms, health professionals in contact with COVID-19 patients, and during pregnancy), abstaining from coital/oral/anal sex, substituting it with masturbatory or virtual sexual activity to provide maximum protection from the contagion, and increasing the benefits inherent to sexual activity are recommended.
    keywords: activity; cov-2; covid-19; days; health; pandemic; partner; risk; sars; sex
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        item: #7526 of 7819
          id: cord-352672-gjo29e21
      author: Hoque, E.
       title: Adjusted Dynamics of COVID-19 Pandemic due to Herd Immunity in Bangladesh
        date: 2020-09-05
       words: 5875
      flesch: 53
     summary: https://doi.org/10.1101/2020.09.03.20186957 doi: medRxiv preprint Bangladesh has already implemented various types of control measures to contain the pandemic. This is why, a discussion is surfacing among the public health professionals as though Bangladesh government is expecting to achieve herd immunity [27] .
    keywords: age; bangladesh; covid-19; group; herd; immunity; pandemic; population; preprint
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        item: #7527 of 7819
          id: cord-352678-8f2ygul2
      author: Prasad, Ashish
       title: Single Virus Targeting Multiple Organs: What We Know and Where We Are Heading?
        date: 2020-08-05
       words: 3497
      flesch: 40
     summary: In another study with COVID-19 patients in China, an early response of IgA instead of IgG was observed in the humoral immune response against SARS-CoV-2 (11) . It has been observed that 5% of COVID-19 patients become critically ill with severe pneumonia and multiple-organ damage and cytokine storm might be a possible explanation for such an observation.
    keywords: coronavirus; cov-2; covid-19; disease; infection; patients; sars; symptoms; virus
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        item: #7528 of 7819
          id: cord-352682-deh08rh4
      author: Toughza, Jihane
       title: COVID-19 et Greffe de Cellules Souches Hématopoïétiques: Recommandations
        date: 2020-06-20
       words: 1779
      flesch: 32
     summary: f Tous les auteurs ont contribué à la conception et à la conception, à la rédaction et à la révision critique de ce manuscrit. La greffe de CSH, allogénique et autologue, est une thérapeutique incontournable de traitement des maladies graves, congénitales ou acquises de l'hématopoïèse, ainsi que des principaux cancers (9,10) mais pourvoyeuse d'une importante morbi-mortalité secondaire à la toxicité du conditionnement administré, à la réaction du greffon contre l'hôte et au déficit Manuscrit 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61
    keywords: cell; covid-19; patients; transplantation
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        item: #7529 of 7819
          id: cord-352700-8ic7gu5y
      author: Hernandez Cordero, A. I.
       title: Multi-omics highlights ABO plasma protein as a causal risk factor for COVID-19
        date: 2020-10-06
       words: 4270
      flesch: 48
     summary: severe COVID-19 associated loci (Fig. 2a) and 3 with the COVID-19 diagnosis associated 362 loci (Supplementary Table S1 ). The 389 expression of ABO in blood co-localized with severe COVID-19 associated loci.
    keywords: covid-19; expression; genes; license; medrxiv; october; perpetuity; preprint; version
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        item: #7530 of 7819
          id: cord-352720-z1cvjc2y
      author: Díaz-Corvillón, Pilar
       title: Routine screening for SARS CoV-2 in unselected pregnant women at delivery
        date: 2020-09-29
       words: 4063
      flesch: 43
     summary: All neonates born from mothers with confirmed SARS CoV-2 were isolated and tested for SARS CoV-2 infection. To assess the prevalence of SARS CoV-2 infection in an unselected obstetrical population and to describe their presentation and clinical evolution.
    keywords: cases; cov-2; infection; patients; population; prevalence; sars; study
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        item: #7531 of 7819
          id: cord-352737-3ttrx3lf
      author: Cunha, Lucas Leite
       title: Remodeling of the Immune Response With Aging: Immunosenescence and Its Potential Impact on COVID-19 Immune Response
        date: 2020-08-07
       words: 6832
      flesch: 27
     summary: In fact, diet, exercise, xenobiotic exposure, and other environmental factors may epigenetically affect the metabolic health of immune cells (22) . Reduced neutrophil chemotaxis and infiltration contributes to delayed resolution of cutaneous wound infection with advanced age Granule exocytosis mediates immune surveillance of senescent cells Reduced release and binding of perforin at the immunological synapse underlies the age-related decline in natural killer cell cytotoxicity Age-related changes in natural killer cell receptors from childhood through old age Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence Age-related alterations in the inflammatory response to dermal injury Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion Peripheral blood dendritic cells and monocytes are differently regulated in the elderly Aging of the innate immune system Neutrophil extracellular traps kill bacteria Deficiency of adenosine deaminase 2 triggers adenosinemediated NETosis and TNF production in patients with DADA2 Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals Senescence in innate immune responses: reduced neutrophil phagocytic capacity and CD16 expression in elderly humans Effect of age on human neutrophil function Neutrophil ageing and immunesenescence Cellular signaling in the aging immune system Signal transduction and functional changes in neutrophils with aging Effects of aging on triggering receptor expressed on myeloid cells (TREM)-1-induced PMN functions Leukocyte function and life span in a murine model of premature immunosenescence Relation of behaviour and macrophage function to life span in a murine model of premature immunosenescence Oxidativeinflammatory stress in immune cells from adult mice with premature aging Premature aging in behavior and immune functions in tyrosine hydroxylase haploinsufficient female mice.
    keywords: age; aging; cells; cov-2; covid-19; disease; immune; immunosenescence; patients; response; sars; system
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        item: #7532 of 7819
          id: cord-352767-lnsi3av0
      author: Teuwen, Laure-Anne
       title: COVID-19: the vasculature unleashed
        date: 2020-05-21
       words: 1589
      flesch: 26
     summary: As hijacking of the host metabolism is essential for virus replication and propagation, an outstanding question is whether EC subtypes or other vascular cells in specific pathological conditions have a metabolic phenotype that is more attractive to SARS-CoV-2. Although the hypothetical role and therapeutic targetability of the vasculature in COVID-19 require further validation, the possibility that ECs and other vascular cells are important players paves the way for future therapeutic opportunities.
    keywords: cells; covid-19; ecs; patients; vascular
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        item: #7533 of 7819
          id: cord-352770-6mz9abmc
      author: Daly, Michael
       title: Psychological distress and adaptation to the COVID-19 crisis in the United States
        date: 2020-10-27
       words: 3740
      flesch: 47
     summary: By June 24-July 20, distress levels were similar to baseline levels (on average) across mental health conditions. Distress levels subsequently declined to mid-March levels by June, 2020 (d =-.31, 95% CI
    keywords: covid-19; distress; health; levels
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        item: #7534 of 7819
          id: cord-352774-dpgk9bvc
      author: Graziani, A.
       title: Pulmonary artery thrombosis in COVID-19 patients
        date: 2020-08-24
       words: 767
      flesch: 33
     summary: (*) P< 0,05 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan Thromboinflammation and the hypercoagulability of COVID-19 Ematological findings and complications of COVID-19 Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Pathological findings of COVID-19 associated with acute respiratory distress syndrome Disseminated intravascular coagulation in patients with 2019-nCoV pneumonia Pulmonary Embolism in COVID-19 Patients: Awareness of an Increased Prevalence Incidence of venous thromboembolism in hospitalized patients with COVID-19 Pulmonary Embolism on CTPA in COVID-19 Patients Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Pulmonary Embolism or Pulmonary Thrombosis in COVID-19? In this paper we reported COVID-19 patients with interstitial pneumonia admitted in our non-ICU Ward.
    keywords: covid-19; patients; pulmonary
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        item: #7535 of 7819
          id: cord-352779-zdtpnip0
      author: Patti, Ravi Karan
       title: Subacute Aspergillosis “Fungal Balls” Complicating COVID-19
        date: 2020-10-15
       words: 1552
      flesch: 32
     summary: Commonly known manifestations of Aspergillosis sp are aspergilloma, allergic bronchopulmonary aspergillosis, invasive pulmonary aspergillosis (IPA), tracheobronchial aspergillosis, and chronic pulmonary aspergillosis. Subacute invasive pulmonary aspergillosis as a superimposed infection in patients with SARS-CoV-2 is a rare entity.
    keywords: aspergillosis; covid-19; infection; sars; subacute
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        item: #7536 of 7819
          id: cord-352781-aqh9zxgh
      author: El Homsi, Maria
       title: Review of Chest CT Manifestations of COVID-19 Infection
        date: 2020-06-07
       words: 3810
      flesch: 41
     summary: Here, we review the pertinent clinical findings and the current published data describing chest CT findings in COVID-19 pneumonia, the diagnostic performance of CT for diagnosis, including differential diagnosis, as well the evolving role of imaging in this disease. In their statement, they also note that with further research, information gained from a baseline CT in COVID-19 patients may play an important role in predicting who will have poor outcomes or need ventilation.
    keywords: chest; coronavirus; covid-19; disease; findings; patients; pneumonia
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        item: #7537 of 7819
          id: cord-352786-wxwjlvmb
      author: Vendrik, J.
       title: The Netherlands Heart Journal: special issue on COVID-19
        date: 2020-07-16
       words: 873
      flesch: 30
     summary: To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. SARS-CoV-2/COVID-19: a primer for cardiologists Chloroquine-induced QTc prolongation in COVID-19 patients The risk of QTc-interval prolongation in COVID-19 patients treated with chloroquine The 'president's drug' Renin-angiotensin system inhibition in COVID-19 patients Cardiac function inrelationtomyocardial injury inhospitalisedpatientswith COVID-19 An international survey in Latin America on the practice of interventional cardiology during the COVID-19 pandemic, with a particular focus on myocardial infarction Recommendations on how to provide cardiac rehabilitation services during the COVID-19 pandemic Ongoing transcatheter aortic valve implantation (TAVI) practice amidst a global COVID-19 crisis: nurse-led analgesia for transfemoral TAVI Return to sports after COVID-19: a position paper of the Dutch Sports Cardiology Section of the Netherlands Society of Cardiology We hope that the readers of this journal find this information valuable for their care of cardiac patients in these unusual circumstances during the COVID-19 pandemic.
    keywords: covid-19; pandemic; patients
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        item: #7538 of 7819
          id: cord-352823-1os3kwp1
      author: Zeng, Hui
       title: The strategies of perioperative management in orthopedic department during the pandemic of COVID-19
        date: 2020-10-15
       words: 3075
      flesch: 41
     summary: We had benefited from the strict flowcharts, smart robot, and protection equipment during the perioperative managements for orthopedic patients. Reasonable treatment strategies were changed and adopted timely to minimize the adverse effects on the treatment of orthopedic patients during the epidemic.
    keywords: covid-19; epidemic; hospital; operation; orthopedic; patients; staff; treatment
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        item: #7539 of 7819
          id: cord-352828-4ecik6xw
      author: Lagziel, Tomer
       title: Two False Negative Test Results in a Symptomatic Patient with a Confirmed Case of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and Suspected Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN)
        date: 2020-05-19
       words: 2442
      flesch: 38
     summary: Treatment of skin drug reactions has the additional challenge of the unknown effects of systemic steroids, which has been a mainstay of treatment for these conditions in COVID-19 positive patients [16] . In addition, the burn unit lacks negative pressure rooms suited for COVID-19 patients.
    keywords: burn; covid-19; patient; results; syndrome; test
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        item: #7540 of 7819
          id: cord-352853-9a7fi46y
      author: Amyar, Amine
       title: Multi-task Deep Learning Based CT Imaging Analysis For COVID-19 Pneumonia: Classification and Segmentation
        date: 2020-10-08
       words: 5817
      flesch: 52
     summary: For image segmentation, several works have shown the power and robustness of these methods [5] . Experiment 2: In Table 2 , the best results for image segmentation was obtained using our method with a dice_coef of 88% versus 77.69% and 76.69% using U-NET with 256 x 256 and 512 x 512 resolutions respectively.
    keywords: classification; covid-19; images; learning; model; results; segmentation; tasks
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        item: #7541 of 7819
          id: cord-352862-2q4h3bwj
      author: Goswami, Mridula
       title: Dealing with “Coronavirus Pandemic”: A Dental Outlook
        date: 2020
       words: 3958
      flesch: 51
     summary: Since dental professionals perform procedures which create aerosols and are in direct contact with saliva and blood, the exposure risk is high among dentists. The declarations issued by these various organizations prove the threatening nature of the current situation for dental professionals.
    keywords: cases; coronavirus; covid-19; dental; disease; health; infection; pandemic; professionals; world
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        item: #7542 of 7819
          id: cord-352871-0xgjpd80
      author: Pérez Bartolomé, Francisco
       title: Manifestaciones oftalmológicas del SARS-Cov-2: Revisión de la literatura
        date: 2020-08-08
       words: 4225
      flesch: 42
     summary: Además, el drenaje linfático de la mucosa ocular es el mismo que el de la fosa nasal En este estudio sí se halló una correlación positiva entre la severidad de la infección sistémica y la ocular.
    keywords: casos; como; con; conjuntivitis; coronavirus; cov-2; covid-19; cuadro; del; disease; enfermedad; infección; las; los; más; novel; ocular; oculares; pacientes; por; que; sars; sólo; también; una; vía
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        item: #7543 of 7819
          id: cord-352901-ia34l2ml
      author: Natalello, Gerlando
       title: Nailfold capillaroscopy findings in patients with coronavirus disease 19: Broadening the spectrum of covid-19 microvascular involvement()
        date: 2020-09-17
       words: 3664
      flesch: 27
     summary: Our aim was to assess microvasculature through nailfold videocapillaroscopy (NVC) in COVID-19 patients. COVID-19 patients present microvascular abnormalities at NVC.
    keywords: acute; alterations; capillaries; covid-19; microvascular; nailfold; nvc; patients
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        item: #7544 of 7819
          id: cord-352902-isc3ek67
      author: Powell, Adam W.
       title: The Adaptation of Pediatric Exercise Testing Programs to the Coronavirus/COVID-19 Pandemic
        date: 2020-09-21
       words: 2776
      flesch: 37
     summary: First, there was an overall small number of pediatric exercise testing programs that responded to the survey. In conclusion, pediatric exercise testing programs have not been immune to the effects of the COVID-19 pandemic, with COVID-19 epidemic: disease characteristics in children Novel Wuhan (2019-nCoV) coronavirus Interim U.S. Guidance for Risk Assessment and Public Health Management of Healthcare Personnel with Strategies to Optimize the Supply of PPE and Equipment Ohio Department of Health.
    keywords: covid-19; exercise; pandemic; programs; survey; testing
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        item: #7545 of 7819
          id: cord-352905-ge3u32hm
      author: Galimberti, Sara
       title: Tyrosine Kinase Inhibitors Play an Antiviral Action in Patients Affected by Chronic Myeloid Leukemia: A Possible Model Supporting Their Use in the Fight Against SARS-CoV-2
        date: 2020-09-02
       words: 5398
      flesch: 33
     summary: Firstly, the infection and replication rate of torquetenovirus (TTV), whose load is inversely proportional to the host immunological control, have been measured in CML patients receiving nilotinib. Consequently, in our opinion, the very low percentage of CML patients found to be SARS-CoV-2 positive could be not explained by the inability of the virus to attack the host cells.
    keywords: abl1; cells; cml; coronavirus; covid-19; imatinib; load; patients; sars; study; treatment; ttv; virus
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        item: #7546 of 7819
          id: cord-352911-9wbq9qo2
      author: de Oliveira, Pedro Gonçalves
       title: Diacerein: a potential multi-target therapeutic drug for COVID-19
        date: 2020-06-01
       words: 2551
      flesch: 36
     summary: After 48 hours, cell cultures will be treated with rhein at different concentrations (1 M to 400 M) for 3, 6, 12, 24, 48 and 72 hours. Rapid reporting and dissemination of results and its consequences regarding the use of hydroxychloroquine for COVID-19 Chloroquine and hydroxychloroquine as available weapons to fight COVID-19 The cytokine storm of severe influenza and development of immunomodulatory therapy Rhein, an anthraquinone drug, suppresses the NLRP3 inflammasome and macrophage activation in urate crystal-induced gouty inflammation Rhein attenuates inflammation through inhibition of NF-κB and NALP3 inflammasome in vivo and in vitro Rhein protects against barrier disruption and inhibits inflammation in intestinal epithelial cells Rhein suppresses lung inflammatory injury induced by human respiratory syncytial virus through inhibiting NLRP3 inflammasome activation via NF-κB pathway in mice Response of young, aged and osteoarthritic human articular chondrocytes to inflammatory cytokines: molecular and cellular aspects Rhein inhibits lipopolysaccharide-induced intestinal injury during sepsis by blocking the toll-like receptor 4 nuclear factor-κB pathway Efficacy and safety of diacerein and diclofenac in knee osteoarthritis in Indian patients -a prospective randomized open label study Rhein prevents endotoxin-induced acute kidney injury by inhibiting NF-κB activities Anti-inflammatory effects of rhein and crude extracts from Cassia alata L. in HaCaT cells Diacerhein downregulate proinflammatory cytokines expression and decrease the autoimmune diabetes frequency in nonobese diabetic (NOD) mice Chrysophanol, an anthraquinone from AST2017-01, possesses the anti-proliferative effect through increasing p53 protein levels in human mast cells Identification of natural compounds with anti-hepatitis B virus activity from
    keywords: anti; cell; coronavirus; cov-2; covid-19; drug; protein; rhein; sars
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        item: #7547 of 7819
          id: cord-352930-onf61i2r
      author: Ostermann, Marlies
       title: What every Intensivist should know about COVID-19 associated acute kidney injury
        date: 2020-07-28
       words: 2536
      flesch: 36
     summary: KDIGO Clinical Practice Guideline for Acute Kidney Injury Management of acute kidney injury in patients with COVID-19 Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target Kidney involvement in COVID-19 and rationale for extracorporeal therapies COVID-19 and the RAAS -a potential role for angiotensin II? Angiotensin II infusion in COVID-19-associated vasodilatory shock: a case series COVID-19 and kidney failure in the acute care setting: our experience from Seattle The Novel Coronavirus 2019 Epidemic and Kidneys Quality improvement goals for acute kidney injury Patient selection and timing of continuous renal replacement therapy Effect of early vs delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury: The ELAIN Randomized Clinical Trial Initiation strategies for renal-replacement therapy in the intensive care unit Timing of renal-replacement therapy in patients with acute kidney injury and sepsis Delayed versus early initiation of renal replacement therapy for severe acute kidney injury: a systematic review and individual patient data meta-analysis of randomised clinical trials Haemodialysis catheters in the intensive care unit Clinical guide for renal replacement therapy options in critical care during the coronavirus pandemic Kidney involvement in COVID-19 and rationale for extracorporeal therapies Survival rate in acute kidney injury superimposed COVID-19 patients: a systematic review and metaanalysis Kidney impairment is associated with in-hospital death of COVID-19 patients The optimal timing for initiation of RRT in COVID-19 patients is unknown [29]
    keywords: acute; aki; covid-19; kidney; patients; renal
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        item: #7548 of 7819
          id: cord-352937-htmp0avc
      author: Chow, Velda Ling Yu
       title: Recommendations for surgical management of recurrent nasopharyngeal carcinoma during COVID‐19 pandemic
        date: 2020-06-13
       words: 2361
      flesch: 35
     summary: Laryngoscope Next-generation surgical navigation systems in sinus and skull base surgery Early results of robotic assisted nasopharyngectomy for recurrent nasopharyngeal carcinoma Combined transnasal endoscopic and transoral robotic resection of recurrent nasopharyngeal carcinoma Letter: Precautions for endoscopic transnasal skull base surgery during the COVID-19 pandemic Safety recommendations for evaluation and surgery of the head and neck during the COVID-19 pandemic Conservation of personal protective equipment for head and neck cancer surgery during COVID-19 pandemic Endoscopic skull base and transoral surgery during the COVID-19 pandemic: minimizing droplet spread with a negative-pressure otolaryngology viral isolation drape (NOVID) Multivariate analysis of prognostic factors for salvage nasopharyngectomy via the maxillary swing approach Surgical salvage of recurrent T3 nasopharyngeal carcinoma: prognostic significance of clivus, maxillary, temporal and sphenoid bone invasion Surgical salvage for recurrent retropharyngeal lymph node metastasis in nasopharyngeal carcinoma Extracranial/intracranial vascular bypass and craniofacial resection: new hope for patients with locally advanced recurrent nasopharyngeal carcinoma Quality of life and survival outcome for patients with nasopharyngeal carcinoma treated by volumetric-modulated arc therapy versus intensity-modulated radiotherapy Silent aspiration and swallowing physiology after radiotherapy in patients with nasopharyngeal carcinoma Quality of life of patients after salvage nasopharyngectomy for recurrent nasopharyngeal carcinoma Recommendations for surgical management of recurrent nasopharyngeal carcinoma during Comprehensive preoperative work‐up, careful patient selection, attention to details perioperation and multidisciplinary approach is essential in ensuring optimal outcomes after salvage surgery for recurrent nasopharyngeal carcinoma patients.
    keywords: carcinoma; covid-19; disease; patients; salvage; surgery; transmission
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        item: #7549 of 7819
          id: cord-352969-rpt7xja6
      author: Kataria, Ashish
       title: COVID-19 in Kidney Transplantation: Epidemiology, Management Considerations, and the Impact on Kidney Transplant Practice
        date: 2020-07-15
       words: 5980
      flesch: 38
     summary: 19 Reverse-transcription polymerase chain reaction (RT-PCR) assay of upper respiratory secretions usually collected with a nasopharyngeal swab is the current diagnostic test of choice for COVID-19 patients. COVID-19 patients have been reported to develop profound lymphopenia.
    keywords: coronavirus; covid-19; data; disease; kidney; ktrs; patients; population; recipients; sars; studies; study; transplant
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        item: #7550 of 7819
          id: cord-352998-02pc3z8n
      author: Huang, Shanshan
       title: COVID‐19 outbreak: The impact of stress on seizures in patients with epilepsy
        date: 2020-08-06
       words: 3977
      flesch: 48
     summary: students' assessments Age limits and adolescents Proposed working definition of an older person in Africa for the MDS Project Intensity of physical activity and subjective well-being: an empirical analysis of the WHO recommendations Factors related to adherence to medication regimens in pediatric seizure patients The PHQ-9: validity of a brief depression severity measure Anxiety disorders in primary care: prevalence, impairment, comorbidity, and detection Psychometric properties of the Sleep Condition Indicator and Insomnia Severity Index in the evaluation of insomnia disorder The Patient Health Questionnaire Somatic, Anxiety, and Depressive Symptom Scales: a systematic review How age, sex and genotype shape the stress response Distribution of seizure precipitants among epilepsy syndromes Sleep deprivation and epilepsy Depression and anxiety in epilepsy Early seizure frequency and aetiology predict long-term medical outcome in childhood-onset epilepsy Individualised prediction model of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs in seizure-free patients: a systematic review and individual participant data meta-analysis Perceived stress and its predictors in people with epilepsy Psychogenic nonepileptic seizure manifestations reported by patients and witnesses Patients' experience of epilepsy and health care Longterm outcomes of children treated with the ketogenic diet in the past Trial of cannabidiol for drug-resistant seizures in the Dravet syndrome The prevalence of anxiety and associated factors in persons with epilepsy Seizures, nonepileptic events, trauma, anxiety, or all of the above This research was supported by funds from the National Key R&D Program of China (grant 2017YFC1310000) and the Fundamental Research Funds for the Central Universities (grant 2019kfyXKJC075). Patients who gave a definite answer to the question of seizure increase and showed an increase in number of seizures during the month of the outbreak as compared to seizure frequency before the outbreak were considered to be PWE with seizure exacerbation during the outbreak of COVID-19.
    keywords: covid-19; epilepsy; outbreak; patients; pwe; seizures; stress; study
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        item: #7551 of 7819
          id: cord-353004-ocnp758o
      author: Prakash, Lakshmanan
       title: COVID-19 in the operating room: a review of evolving safety protocols
        date: 2020-07-20
       words: 4379
      flesch: 46
     summary: Theoretically, viremia in patients with asymptomatic or confirmed COVID-19 patients could pose a risk of transmissibility to the orthopedic team during aerosolized-blood generating procedures. Health Leaders Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan Surgery in COVID-19 patients: operational directives Clinical characteristics and outcomes of patients undergoing surgeries during the incubation period of COVID-19 infection Immune function after major surgical interventions: the effect of postoperative pain treatment Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis Temporal changes in cytokine/chemokine profiles and pulmonary involvement in severe acute respiratory syndrome Chemokine up-regulation in SARS-coronavirus-infected, monocytederived human dendritic cells Neurosurgeon dies of COVID-19.
    keywords: coronavirus; covid-19; pandemic; patients; procedures; room; staff; surgeons; surgery
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        item: #7552 of 7819
          id: cord-353019-7wj0eu1f
      author: Alcadipani, Rafael
       title: Pandemic and Macho Organizations: Wakeup Call or Business as Usual?
        date: 2020-05-13
       words: 7183
      flesch: 60
     summary: In this reflection, I will discuss this issue based on ethnographic research I have been doing with police detectives in Brazil. I am part of some police detectives' instant messaging groups and I can also easily reach police detectives via instant messaging and phone calls.
    keywords: brazil; covid-19; detectives; gender; macho; masculinity; organization; pandemic; police; virus; work
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        item: #7553 of 7819
          id: cord-353058-3r6jw5ij
      author: Crotti, Lia
       title: COVID-19 treatments, QT interval and arrhythmic risk: the need for an international Registry on Arrhythmias
        date: 2020-05-26
       words: 1250
      flesch: 38
     summary: 2020 Enhanced ECG monitoring of COVID-19 patients The QT Interval in Patients with SARS-CoV-2 Infection Treated with Hydroxychloroquine/Azithromycin The Effect of Chloroquine, Hydroxychloroquine and Azithromycin on the Corrected QT Interval in Patients with SARS-CoV-2 Infection Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19 Effect of High vs Low Doses of Chloroquine Diphosphate as Adjunctive Therapy for Patients Hospitalized With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection: A Randomized Clinical Trial A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19 Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial. Indeed, there are already few studies that evaluated QTc and arrhythmic risk in hospitalized COVID-19 patients treated with different QT-prolonging drugs (i.e. hydroxychloroquine/chloroquine, azithromycin, lopinavir/ritonavir).
    keywords: covid-19; patients
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        item: #7554 of 7819
          id: cord-353059-39msyuxb
      author: Chroboczek, T.
       title: Beneficial effect of corticosteroids in severe COVID-19 pneumonia: a propensity score matching analysis.
        date: 2020-05-13
       words: 3478
      flesch: 44
     summary: https://doi.org/10.1101/2020.05.08.20094755 doi: medRxiv preprint Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan: A Retrospective Observational Study Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Clinical Features of 69 Cases with Coronavirus Disease A Novel Coronavirus from Patients with Pneumonia in China A pneumonia outbreak associated with a new coronavirus of probable bat origin Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China Prognostic value of interleukin-6, C-reactive protein, and procalcitonin in patients with COVID-19 Rational Use of Tocilizumab in the Treatment of Novel Coronavirus Pneumonia Detectable serum SARS-CoV-2 viral load COVID-19: consider cytokine storm syndromes and immunosuppression Effective treatment of severe COVID-19 patients with tocilizumab Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in patients with severe COVID-19 Clinical Outcomes of Hydroxychloroquine in Hospitalized Patients with COVID-19: In our hospital, the ICU is usually composed of 15 beds only; at the peak of the first wave of the pandemic, it required deep reorganization, and extension of its capacity to 35 beds, due to the strong increase in the number of COVID-19 ventilated patients.
    keywords: covid-19; license; medrxiv; patients; preprint; study; treatment
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        item: #7555 of 7819
          id: cord-353064-x4dcfjm8
      author: Carlos, Ruth C.
       title: Defining the Recovery
        date: 2020-07-01
       words: 1358
      flesch: 44
     summary: Intensity and duration of COVID-19 care delivery and the impact on ability to resume elective services vary immensely with downstream consequences on institutional and practice losses, potential reduction in staff, and compensation reduction. Multiple institutions present their data showing the magnitude and time course for imaging reduction rates that reflect their institution capacity, their local rate of COVID-19 infections, and state-level shelter-in-place regulations [2] [3] [4]
    keywords: care; coronavirus; covid-19; disease; pandemic
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        item: #7556 of 7819
          id: cord-353072-n92atcrx
      author: Kadkhoda, Kamran
       title: COVID-19: an Immunopathological View
        date: 2020-04-22
       words: 2047
      flesch: 37
     summary: Pathological findings of COVID-19 associated with acute respiratory distress syndrome Pulmonary pathological features in coronavirus associated severe acute respiratory syndrome (SARS) Exacerbated innate host response to SARS-CoV in aged non-human primates Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19). World Health Organization Prevalence of antibodies to four human coronaviruses is lower in nasal secretions than in serum Human coronavirus in young children hospitalized for acute respiratory illness and asymptomatic controls Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus.
    keywords: ade; cells; coronavirus; covid-19; receptor; sars; syndrome
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        item: #7557 of 7819
          id: cord-353110-0oxy9b1p
      author: Hastie, Claire E.
       title: Vitamin D concentrations and COVID-19 infection in UK Biobank
        date: 2020-05-07
       words: 2343
      flesch: 44
     summary: We aimed to establish whether blood 25-hydroxyvitamin D (25(OH)D) concentration was associated with COVID-19 risk, and whether it explained the higher incidence of COVID-19 in black and South Asian people. • We explored whether blood 25 hydroxyvitamin D (25(OH)D) concentration was associated with COVID-19 risk among UK Biobank participants, and whether this explained wholly, or in part, the higher incidence of COVID-19 infection in ethnic minority participants.
    keywords: 25(oh)d; biobank; covid-19; infection; risk; vitamin
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        item: #7558 of 7819
          id: cord-353113-peqzaupr
      author: Wang, Yan
       title: Case Report: Opportunities for Treatment of Severe COVID-19 Patients—Lessons From a Death Case
        date: 2020-08-14
       words: 2370
      flesch: 48
     summary: Another lesson is the risk involved in transferring severe COVID-19 patients. Currently, many patients require invasive mechanical ventilation and transfer to a superior hospital.
    keywords: covid-19; february; patient; ventilation
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        item: #7559 of 7819
          id: cord-353116-7t1prfkr
      author: Bhargava, Ashish
       title: Predictors for Severe COVID-19 Infection
        date: 2020-05-30
       words: 2636
      flesch: 50
     summary: Predictors for severe COVID-19 infection have not been well defined. Severe COVID-19 infection was noted in 74 (37.6%) patients, requiring intubation.
    keywords: covid-19; crp; disease; infection; patients; risk
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        item: #7560 of 7819
          id: cord-353163-gr1t3l8z
      author: Hughes, Helen E
       title: Emergency department use during COVID-19 as described by syndromic surveillance
        date: 2020-09-18
       words: 2126
      flesch: 48
     summary: This retrospective observational analysis of EDSSS data aimed to describe changes in ED attendances during March–April 2020, and identify the attendance types with the largest impact. Daily ED attendance data were accessed from EDSSS from 1 January 2019 to 26 April 2020 (routine, anonymised, public health surveillance data, no ethical approval required).
    keywords: attendances; covid-19; data; edsss; surveillance
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        item: #7561 of 7819
          id: cord-353173-5c4n4tsf
      author: Comunian, Silvia
       title: Air Pollution and COVID-19: The Role of Particulate Matter in the Spread and Increase of COVID-19’s Morbidity and Mortality
        date: 2020-06-22
       words: 8328
      flesch: 42
     summary: Air pollution is also one of the greatest challenges of our millennium, and some early studies have highlighted a positive correlation between air pollution and the spread of the virus. The authors conclude that there is a statistically significant relationship between short-term exposure to higher air pollution and an increased risk of Covid-19 infection.
    keywords: air; air pollution; analysis; cells; covid-19; exposure; increase; lung; particles; pm10; pm2.5; pollutants; pollution; response; virus
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        item: #7562 of 7819
          id: cord-353196-pbjrgyj2
      author: Keeney, Tamra
       title: Physical Therapy in the COVID-19 Pandemic: Forging a Paradigm Shift for Rehabilitation in Acute Care
        date: 2020-05-26
       words: 1160
      flesch: 18
     summary: Although rehabilitation utilization in hospitals varies enormously based on institution size, financial resources, and geographic location, it is clear that even in settings where acute care physical therapy is well staffed and well-funded, expansion of our roles is essential. This lack of focus on acute care rehabilitation is due, at least in part, to the perceived role of inpatient physical therapists as discharge consultants.
    keywords: care; patients; physical; rehabilitation
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        item: #7563 of 7819
          id: cord-353200-5csewb1k
      author: Jehi, Lara
       title: Development and validation of a model for individualized prediction of hospitalization risk in 4,536 patients with COVID-19
        date: 2020-08-11
       words: 4349
      flesch: 35
     summary: After that date, testing resources were streamlined through a COVID-19 Hotline which followed recommendations from the Centers for Disease Control (recommending to focus on high risk patients as defined by any of the following: Age older than 60 years old or less than 36 months old; on immune therapy; having comorbidities of cancer, end-stage renal disease, diabetes, hypertension, coronary artery disease, heart failure with reduced ejection fraction, lung disease, HIV/AIDS, solid organ transplant; contact with known COVID 19 patients; physician discretion was still allowed). Table 1 provides demographic, exposure, clinical, laboratory, social characteristics, and medication history of COVID-19 patients who were hospitalized versus those who completed their treatment on an outpatient basis in both the DC and VC.
    keywords: cohort; covid-19; data; disease; health; hospitalization; model; patients; prediction; risk; variables
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        item: #7564 of 7819
          id: cord-353228-fxrf5wsp
      author: Xiao, Yaru
       title: Clinical characteristics of diarrhea in 90 cases with COVID-19: a descriptive study
        date: 2020-08-08
       words: 1643
      flesch: 50
     summary: It is worth noting that COVID-19 patients with mild to moderate liver injuries, including elevated aminotransferases and hypoproteinemia, have also been reported, and some of the patients had digestive system impairment 11 . Among the gastrointestinal symptoms in COVID-19 cases including diarrhea, nausea, vomiting, and abdominal pain, diarrhea is the one that possibly increases the chance of potential fecal-oral transmission but could be easily overlooked by health care workers.
    keywords: cases; covid-19; diarrhea; patients
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        item: #7565 of 7819
          id: cord-353229-k3zerr83
      author: Akca, Ummusen Kaya
       title: Kawasaki-like disease in children with COVID-19
        date: 2020-09-16
       words: 4380
      flesch: 38
     summary: Coronavirus Disease 2019 in Children-United States Epidemiology and clinical features of coronavirus disease 2019 in children Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China New spectrum of COVID-19 manifestations in children: Kawasaki-like syndrome and hyperinflammatory response Predictors of COVID-19 severity: a literature review Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic Paediatric inflammatory multisystem syndrome and SARS-CoV-2 infection in children Viral infections associated with Kawasaki disease Association between a novel human coronavirus and Kawasaki disease Kawasaki disease and infection Detection of Epstein-Barr virus DNA in cardiac and aortic tissues from chronic, active Epstein-Barr virus infection associated with Kawasaki disease-like coronary artery aneurysms An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study Hyperinflammatory shock in children during COVID-19 pandemic Acute myocarditis and multisystem inflammatory emerging disease following SARS-CoV-2 infection in critically ill children Pediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort Multisystem inflammatory syndrome in US children and adolescents Intensive care admissions of children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) in the UK: a multicentre observational study Diagnosis, treatment, and long-term management of Kawasaki disease: a scientific statement for health professionals from the American Heart Association COVID-19 and Kawasaki disease: novel virus and novel case SARS-CoV-2-induced kawasaki-like hyperinflammatory syndrome: a novel COVID phenotype in Children Incomplete Kawasaki disease in a child with COVID-19 COVID-19 associated pediatric multi-system inflammatory Syndrome Erythema multiforme and Kawasaki disease associated with COVID-19 infection in children Multisystem inflammatory syndrome in children during the COVID-19 pandemic: a case series Features of COVID-19 post-infectious cytokine release syndrome in children presenting to the emergency department Dermatological manifestation of pediatrics multisystem inflammatory syndrome associated with COVID-19 in a 3-year-old girl Multisystem inflammatory syndrome with features of atypical Kawasaki disease during COVID-19 pandemic A case of pediatric multisystem inflammatory syndrome temporally associated with COVID-19 in South Dakota Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 Toxic shock-like syndrome and COVID-19: a case report of multisystem inflammatory syndrome in children (MIS-C) Patterns of myocardial involvement in children during COVID-19 pandemic: Early experience from northern Italy COVID-19 multisystem inflammatory syndrome in three teenagers with confirmed SARS-CoV-2 infection Paediatric inflammatory multisystem syndrome: temporally associated with SARS-CoV-2 (PIMS-TS): cardiac features, management and short-term outcomes at a UK Tertiary Paediatric Hospital Multisystem Inflammatory Syndrome Related to COVID-19 in previously healthy children and adolescents in New York City Severe COVID-19 in children and young adults in the Washington, DC metropolitan region Characteristics, cardiac involvement, and outcomes of multisystem inflammatory disease of childhood (MIS-C) associated with SARS-CoV-2 infection Emergence of Kawasaki disease related to SARS-CoV-2 infection in an epicentre of the French COVID-19 epidemic: a time-series analysis Cardiac MRI of children with multisystem inflammatory syndrome (MIS-C) associated with COVID-19: case series Serology confirms SARS-CoV-2 infection in PCR-negative children presenting with Paediatric Inflammatory Multi-System Syndrome Incomplete Kawasaki disease as presentation of COVID-19 infection in an infant: a case report Kawasaki Disease features and myocarditis in a patient with COVID-19 Distinct clinical and immunological features of SARS-COV-2-induced multisystem inflammatory syndrome in children SARS-COV-2 Infection and Kawasaki Disease: case report of a Hitherto Unrecognized Association. This finding suggests that we should maintain a high index of suspicion for incomplete KD in COVID-19 patients.
    keywords: children; covid-19; disease; incomplete; kawasaki; manuscript; multisystem; patients; sars; syndrome
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        item: #7566 of 7819
          id: cord-353235-jiqhgf56
      author: Bigliardi, Guido
       title: Middle cerebral artery ischemic stroke and COVID-19: a case report
        date: 2020-09-08
       words: 1067
      flesch: 41
     summary: Lupus anticoagulant and anti-phospholipid antibodies have also been described in COVID-19 patients with thrombotic events (Helms et al. 2020; Zhang et al. 2020 ), but a causal relation has not been proven. This case underlines the importance of constant neurological monitoring in COVID-19 patients during ICU staying, especially in those with suspected thrombotic events, to detect possible neurological complications.
    keywords: covid-19; sars
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        item: #7567 of 7819
          id: cord-353254-8xa0is5g
      author: Katzman, Joanna G
       title: COVID-19 Has Provided 20/20 Vision Illuminating Our Nation’s Health Crises
        date: 2020-09-28
       words: 901
      flesch: 32
     summary: Our Health is the Public's Health: Pain Management Leadership in the COVID-19 Pandemic Prevalence of Chronic Pain and High-Impact Chronic Pain Among Adults-United States Key substance use and mental health indicators in the United States: Results from the 2018 National Survey on Drug Use and Health Drug Overdose Deaths in the United States Increase in Suicide Mortality in the United States Psychological Distress and Loneliness Reported by US Adults Loneliness and social isolation as risk factors for mortality Loneliness matters: a theoretical and empirical review of consequences and mechanisms Loneliness as a public health issue: the impact of loneliness on health care utilization among older adults Working to Address the Loneliness Epidemic: Perspective-Taking, Presence, and Self-Disclosure Collision of the COVID-19 and Addiction Epidemics Pain Management Best Practices from Multispecialty Organizations During the COVID-19 Pandemic and Public Health Crises The ethics of PPE and EMS in the COVID-19 Era A call to protect patients, correctional staff and healthcare professionals in jails and prisons during the COVID-19 pandemic The impact of the COVID-19 pandemic on cancer care Oncology Practice During the COVID-19 Impact of the COVID-19 Epidemic on Stroke Care and Potential Solutions Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era Signal of increased opioid overdose during COVID-19 from emergency medical services data Compound climate risks in the COVID-19 pandemic ECHO Telementoring for Pain, Palliative Care, and Opioid Management: Progress, Challenges, and Future Goals 2020 Virtually Perfect? They are both underlying forces tying many health crises together.
    keywords: covid-19; health; loneliness
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        item: #7568 of 7819
          id: cord-353275-pindjvhk
      author: Khurana, A.
       title: Prevalence and clinical correlates of COVID-19 outbreak among healthcare workers in a tertiary level hospital
        date: 2020-07-24
       words: 4287
      flesch: 49
     summary: (Table 7 and 8) 3.7 Hand Hygiene practices among Health care Workers Participants in the group COVID positive group had the larger proportion of people who washed hands for over 20 seconds than the control group, but the difference did not attain significance. Table 4 Distribution of chronic medical conditions among positive healthcare workers and control group .
    keywords: covid-19; group; july; license; medrxiv; perpetuity; preprint; version
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        item: #7569 of 7819
          id: cord-353281-leb7c7b0
      author: Spiezia, Luca
       title: COVID-19-Related Severe Hypercoagulability in Patients Admitted to Intensive Care Unit for Acute Respiratory Failure
        date: 2020-04-21
       words: 1141
      flesch: 35
     summary: Interestingly enough, markedly hypercoagulable thromboelastometry profiles were observed in COVID-19 patients, as reflected by shorter Clot Formation Time (CFT) in INTEM ( p = 0.0002) and EXTEM ( p = 0.01) and higher Maximum Clot Firmness (MCF) in INTEM, EXTEM and FIBTEM ( p < 0.001 in all comparisons). In conclusion, COVID-19 patients with acute respiratory failure present a severe hypercoagulability rather than consumptive coagulopathy.
    keywords: covid-19; patients; profiles; study
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        item: #7570 of 7819
          id: cord-353283-rlvfk8w8
      author: Liu, D.
       title: Pleotropic association between risk and prognosis of COVID-19 and gene expression in blood and lung: A Mendelian randomization analysis
        date: 2020-09-03
       words: 3222
      flesch: 47
     summary: A recent retrospective study of 77 adults found that IFN-α2b treatment with or without arbidol significantly reduced the duration of detectable virus in the upper respiratory tract of COVID-19 patients (24). It was estimated that approximately 40% of COVID-19 patients were considered All rights reserved.
    keywords: analysis; blood; covid-19; data; eqtl; medrxiv; preprint
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        item: #7571 of 7819
          id: cord-353293-vjdwh19x
      author: None
       title: Post-COVID-19 global health strategies: the need for an interdisciplinary approach
        date: 2020-06-11
       words: 3861
      flesch: 32
     summary: It therefore appears appropriate to propose a detailed model for the first assessment (minimum data set for the assessment of COVID-19 patients), providing that subsequent stages can be customized based on the initial findings ( Table 1) . Nothing is known about long-term respiratory sequelae in COVID-19 patients.
    keywords: assessment; care; covid-19; disease; infection; patients; phase; post; risk; sars
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        item: #7572 of 7819
          id: cord-353312-9hd54ug5
      author: Al‐Hebshi, Abdulqader
       title: A Saudi family with sickle cell disease presented with acute crises and COVID‐19 infection
        date: 2020-07-10
       words: 547
      flesch: 45
     summary: In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Early hydroxychloroquine is associated with an increase of survival in Covid-19 patients: an observational study Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury Beneficial effect of intravenous dexamethasone in children with mild to moderately severe acute chest syndrome complicating sickle cell disease The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak Rapid and severe Covid-19 pneumonia with severe acute chest syndrome in a sickle cell patient successfully treated with tocilizumab key: cord-353312-9hd54ug5 authors: Al‐Hebshi, Abdulqader; Zolaly, Mohammed; Alshengeti, Amer; Al Qurainees, Ghaya; Yamani, Sofyan; Hamdan, Naif; Alwasaidi, Turki title: A Saudi family with sickle cell disease presented with acute crises and COVID‐19 infection date: 2020-07-10 journal: Pediatr Blood Cancer DOI: 10.1002/pbc.28547 sha: doc_id: 353312 cord_uid: 9hd54ug5 nan Evidence about COVID-19 in children is evolving, but many questions are still unanswered.
    keywords: blood; covid-19
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        item: #7573 of 7819
          id: cord-353321-56zhxd6e
      author: Ma, Shujuan
       title: Epidemiological parameters of coronavirus disease 2019: a pooled analysis of publicly reported individual data of 1155 cases from seven countries
        date: 2020-03-24
       words: 5693
      flesch: 48
     summary: By contrast, this study followed strict inclusion criteria regarding exposure period and method to determine exposure date to ensure the potential error in the estimates be small (< 0.3 day, according to the sensitivity analysis). 8,9,14-17 Stratified analysis in this study found a trend towards longer incubation period of less severe cases as compared with that of more severe cases.
    keywords: cases; days; exposure; incubation; interval; period
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        item: #7574 of 7819
          id: cord-353329-ju3vwlow
      author: Haroon, Khawaja Hassan
       title: COVID-19 Related Cerebrovascular Thromboembolic Complications in Three Young Patients
        date: 2020-09-28
       words: 2018
      flesch: 53
     summary: Recently, three main mechanisms, including hypercoagulopathy, vasculitis and cardiomyopathy leading to stroke in COVID-19 patients, have been described, while the role of various vascular and immune-mediated factors in the pathogenesis of stroke in these patients remain unclear [7] . Still, there remains uncertainty about the mechanisms and treatment options for stroke in COVID-19 patients.
    keywords: cov-2; covid-19; patients; right; sars; stroke
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        item: #7575 of 7819
          id: cord-353354-34tqy9tb
      author: Sheshah, Eman
       title: Prevalence of Diabetes, Management and Outcomes among Covid-19 Adult Patients Admitted in a Specialized Tertiary Hospital in Riyadh, Saudi Arabia
        date: 2020-11-13
       words: 3362
      flesch: 45
     summary: In this single-center study, T2DM was very common among hospitalized Covid-19 patients. Table 1 shows the general characteristics of 300 hospitalized Covid-19 patients in KSH.
    keywords: arabia; covid-19; mortality; patients; saudi; study
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        item: #7576 of 7819
          id: cord-353365-ujz5nkk3
      author: Pirnay, Jean-Paul
       title: Study of a SARS-CoV-2 Outbreak in a Belgian Military Education and Training Center in Maradi, Niger
        date: 2020-08-27
       words: 4785
      flesch: 48
     summary: Based, among others, on this epidemiological study, the medical military command decided to continue testing Belgian soldiers for SARS-CoV-2 viral load and antibodies, and this two to three days before a mission abroad or on the high seas, and for specific missions immediately upon their return. Five of them exhibited COVID-19 symptoms (mainly anosmia, ageusia, and fever), while four were asymptomatic.
    keywords: belgium; cov-2; covid-19; data; genomes; maradi; military; niger; samples; sars; soldiers; symptoms; table
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        item: #7577 of 7819
          id: cord-353373-zhkqnu0w
      author: Seidu, Samuel
       title: The impact of obesity on severe disease and mortality in people with SARS‐CoV‐2: A systematic review and meta‐analysis
        date: 2020-08-14
       words: 2877
      flesch: 42
     summary: The review was limited by the small number of included studies, the absence of some key data and the lack of quantitative synthesis. key: cord-353373-zhkqnu0w authors: Seidu, Samuel; Gillies, Clare; Zaccardi, Francesco; Kunutsor, Setor K.; Hartmann‐Boyce, Jamie; Yates, Thomas; Singh, Awadhesh Kumar; Davies, Melanie J.; Khunti, Kamlesh title: The impact of obesity on severe disease and mortality in people with SARS‐CoV‐2: A systematic review and meta‐analysis date: 2020-08-14 journal: Endocrinol Diabetes Metab DOI: 10.1002/edm2.176 sha: doc_id: 353373 cord_uid: zhkqnu0w BACKGROUND:
    keywords: covid-19; disease; obesity; patients; people; risk; studies
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        item: #7578 of 7819
          id: cord-353391-o0s2h0y0
      author: Haj Bloukh, Samir
       title: A Look Behind the Scenes at COVID-19: National Strategies of Infection Control and Their Impact on Mortality
        date: 2020-08-04
       words: 9943
      flesch: 54
     summary: The number of COVID-19 cases in Italy was 233,197 with a population size of 60,431,283 and 33,475 fatalities until 2 June of 2020 ( Figure 4 ) The indoor environment in summer may cause aggravated SARS-CoV-2 transmission patterns and an increase in COVID-19 cases and fatalities.
    keywords: cases; control; countries; cov-2; covid-19; fatalities; figure; health; measures; number; pandemic; sars
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        item: #7579 of 7819
          id: cord-353410-tbmtg88k
      author: Sharma, Shreela V.
       title: Using a rapid assessment methodology to identify and address immediate needs among low-income households with children during COVID-19
        date: 2020-10-01
       words: 3947
      flesch: 49
     summary: Brighter Bites response to high risk families: In response to these aforementioned needs, Brighter Bites pivoted and created an infrastructure and a standardized framework to meet the needs of these high-risk families (see Fig 1) . A tracking database was created, in which all phone calls and family concerns were tracked for each family.
    keywords: bites; covid-19; families; food; health; needs; risk; survey
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        item: #7580 of 7819
          id: cord-353445-0n51j2jo
      author: Stein-Zamir, Chen
       title: A large COVID-19 outbreak in a high school 10 days after schools’ reopening, Israel, May 2020
        date: 2020-07-23
       words: 2086
      flesch: 57
     summary: With the emergence of two unrelated cases within 2 days, the district health office declared an 'outbreak status' including school closure, isolation instructions and testing of the school community. School closure is a public health tool in influenza pandemic preparedness plans, based on high infectiousness and susceptibility in schoolchildren and high contact rates [14] .
    keywords: cases; classes; covid-19; school; staff; students
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        item: #7581 of 7819
          id: cord-353465-pej4e9z0
      author: Ranjan, A.
       title: FeverIQ - A Privacy-Preserving COVID-19 SymptomTracker with 3.6 Million Reports
        date: 2020-09-25
       words: 3176
      flesch: 44
     summary: We then trained a linear classifier on diagnosis scores which were computed securely, without unprotected symptom data ever leaving a user's phone or computer. The Lancet Infect Contact tracing, a key way to slow COVID-19, is badly underused by the U Bottleneck for U.S. coronavirus response: The fax machine Smartphone users will top 3 billion Real-time tracking of self-reported symptoms to predict potential COVID-19 Population-scale longitudinal mapping of COVID-19 symptoms, behavior, and testing identifies contributors to continued disease spread in the United States Estimated effectiveness of symptom and risk screening to prevent the spread of COVID-19 Germany's angst is killing its coronavirus tracing app The re-identification risk of canadians from longitudinal demographics Big data security and privacy in healthcare: A review Adolescents' perceptions of a health survey using multimedia computer-assisted self-administered interview Ethical considerations to guide the use of digital proximity tracking technologies for COVID-19 contact tracing: Interim guidance Multiparty computation from somewhat homomorphic encryption Pulmonary function, chronic respiratory symptoms, and health-related quality of life among adults in the United States -National Health and Nutrition Examination Survey The global impact of respiratory disease Efficient multiparty protocols using circuit randomization ABY -A framework for efficient mixed-protocol secure two-party computation Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo' Estimates of the rate of infection and asymptomatic COVID-19 disease in a population sample from SE England COVID-19 antibody seroprevalence in Advances and open problems in federated learning Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: A descriptive, cross-sectional, multicenter study.
    keywords: covid-19; data; diagnosis; health; privacy; symptoms; test; vectors
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        item: #7582 of 7819
          id: cord-353484-q7d0ysbo
      author: Liu, Xue
       title: COVID-19: Progress in diagnostics, therapy and vaccination
        date: 2020-06-19
       words: 8584
      flesch: 33
     summary: medRxiv Coronaviruses -drug discovery and therapeutic options Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro First Case of 2019 Novel Coronavirus in the United States Compassionate Use of Remdesivir for Patients with Severe Covid-19 Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial Effects of chloroquine on viral infections: an old drug against today's diseases? Efficacy of hydroxychloroquine in patients with COVID-19: results of a randomized clinical trial Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies Treating COVID-19 with Chloroquine Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data Hydroxychloroquine in patients with mainly mild to moderate coronavirus disease 2019: open label, randomised controlled trial Comparative efficacy and safety of second-line antiretroviral therapy for treatment of HIV/AIDS: a systematic review and network meta-analysis Optimizing use of theranostic nanoparticles as a life-saving strategy for treating COVID-19 patients Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings Consideration of highly active antiretroviral therapy in the prevention and treatment of severe acute respiratory syndrome Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture Favipiravir (T-705), a broad spectrum inhibitor of viral RNA polymerase A phase 1/2 trial to evaluate the pharmacokinetics, safety, and efficacy of NI-03 in patients with chronic pancreatitis: study protocol for a randomized controlled trial on the assessment of camostat treatment in chronic pancreatitis (TACTIC) Experimental drugs poised for use in Ebola outbreak Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir Chloroquine is a potent inhibitor of SARS coronavirus infection and spread SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and Other Drugs for the Treatment of the New Coronavirus Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review Experimental Treatment with Favipiravir for COVID-19: An Open-Label Control Study. Revised 18 Engineering DNA vaccines against infectious diseases Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial Immunogenicity of a DNA vaccine candidate for COVID-19 Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in-human trial ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques Safety of trivalent inactivated influenza vaccines in adults: background for pandemic influenza vaccine safety monitoring Inactivated poliovirus vaccine: past and present experience Safety and Immunogenicity Study of Inactivated Vaccine for Prophylaxis of SARS CoV-2 Infection (COVID-19) Novavax Initiates Phase 1/2 Clinical Trial of COVID-19 Vaccine.
    keywords: antibodies; antibody; coronavirus; cov-2; covid-19; detection; disease; human; infection; novel; patients; protein; receptor; sars; specific; treatment; trial; vaccines
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        item: #7583 of 7819
          id: cord-353509-yfkiaq80
      author: Nugraha, Rhea Veda
       title: Traditional Herbal Medicine Candidates as Complementary Treatments for COVID-19: A Review of Their Mechanisms, Pros and Cons
        date: 2020-10-10
       words: 7439
      flesch: 45
     summary: Impaired immune regulation is one of the factors that play a role in its pathogenesis and results in poor outcomes of COVID-19 patients. A report showed that COVID-19 patients had an increase in neutrophils, interleukin (IL-6), and C-reactive protein (CRP) and a decrease in lymphocytes.
    keywords: coronavirus; cov-2; covid-19; curcumin; cytokine; disease; effect; patients; protein; quinine; sars; study; treatment; virus
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        item: #7584 of 7819
          id: cord-353515-92qqucyl
      author: Okura, Hiroyuki
       title: Update of Takotsubo Syndrome in the Era of COVID-19
        date: 2020-10-14
       words: 3951
      flesch: 38
     summary: In TTS patients, plasma catecholamine (epinephrine, norepinephrine, and dopamine) levels at presentation were markedly higher than among those with Killip class III myocardial infarction [14] . When patients with a score of ≥50 were diagnosed as having TTS, nearly 95% of TTS patients were correctly diagnosed [25] .
    keywords: acute; cardiomyopathy; coronary; patients; syndrome; takotsubo; tts; ventricular
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        item: #7585 of 7819
          id: cord-353519-cmeociax
      author: Jay Miller, J.
       title: Child Welfare Workers and Peritraumatic Distress: The Impact of COVID-19
        date: 2020-09-25
       words: 4804
      flesch: 44
     summary: This exploratory study examined COVID-19 related peritraumatic distress among child welfare workers (N=1,996) in one southeastern state in the United States (U.S.). Sexual orientation, self-reported physical and mental health, relationship status, supervision status, and financial stability impacted distress levels experienced by child welfare workers.
    keywords: child; child welfare; covid-19; distress; impact; pandemic; study; welfare; welfare workers; workers
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        item: #7586 of 7819
          id: cord-353530-seu53c4s
      author: Bonavita, Simona
       title: Digital triage for people with multiple sclerosis in the age of COVID-19 pandemic
        date: 2020-04-17
       words: 868
      flesch: 46
     summary: key: cord-353530-seu53c4s authors: Bonavita, Simona; Tedeschi, Gioacchino; Atreja, Ashish; Lavorgna, Luigi title: Digital triage for people with multiple sclerosis in the age of COVID-19 pandemic date: 2020-04-17 journal: Neurol Sci DOI: 10.1007/s10072-020-04391-9 sha: doc_id: 353530 cord_uid: seu53c4s We propose a possible approach for the remote monitoring of infection risk in people with multiple sclerosis, especially those on immunosuppressant drugs, during COVID-19 pandemic. The use of digital triage could be personalized (in terms of frequency of invitation) according to the risk level and to the pandemic evolution.
    keywords: covid-19; patients; triage
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        item: #7587 of 7819
          id: cord-353537-skeajydw
      author: Zhang, Xian
       title: Asymptomatic Subclinical Cases of Coronavirus Disease 2019 without Viral Transmission in Three Independent Families
        date: 2020-09-24
       words: 2103
      flesch: 42
     summary: The infectivity of asymptomatic subclinical infection patients of coronavirus disease 2019 seems to be low. Therefore, there is little opportunity to deliberately observe whether asymptomatic patients can infect the surrounding contacts under natural conditions.
    keywords: asymptomatic; cov-2; covid-19; patients; sars
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        item: #7588 of 7819
          id: cord-353548-kf4om6iu
      author: Ruiz-Manriquez, J.
       title: Knowledge of Latin American gastroenterologists and endoscopists regarding SARS-CoV-2 infection
        date: 2020-05-31
       words: 2752
      flesch: 43
     summary: That could be a reason for the lack of knowledge about prevention measures and endoscopic procedure management regarding COVID-19 patients. 2. Critical preparedness, readiness and response actions for COVID-19 Situation Report-66 HIGHLIGHTS Joint GI Society Message on COVID-19 -American College of Gastroenterology Position Statement on gastrointestinal endoscopy and the COVID-19 pandemic Clinical characteristics of COVID-19 patients with digestive symptoms in Hubei, China: a descriptive, cross-sectional Clinical Characteristics of Coronavirus Disease 2019 in China Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: The possible role of dry surface contamination Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 Guideline for Disinfection and Sterilization in Healthcare Facilities Reprocessing of flexible endoscopes and endoscopic accessories used in gastrointestinal endoscopy: Position Statement of the European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastroenterology Nurses and Associates (ESGENA) -Update
    keywords: patients; risk; sars
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        item: #7589 of 7819
          id: cord-353586-motgn69w
      author: Indu Subramanian
       title: Hoping for the best, planning for the worst: Palliative care approach to Parkinson disease during the COVID-19 pandemic
        date: 2020-10-06
       words: 1811
      flesch: 35
     summary: Hospice should be considered for patients who have end-stage PD and whose goals are aligned with hospice care. Shared decision-making tools regarding the appropriateness of hospice care in COVID-19 positive patients can be useful: https://www.nhpco.org/wp-content/uploads/COVID-19-Shared-Decision-Making-Tool.pdf.
    keywords: care; covid-19; palliative; pandemic
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        item: #7590 of 7819
          id: cord-353588-8uyezpko
      author: Casali, Nicole
       title: “Andrà tutto bene”: Associations Between Character Strengths, Psychological Distress and Self-efficacy During Covid-19 Lockdown
        date: 2020-10-13
       words: 7352
      flesch: 35
     summary: Finally, to accomplish the main aim of our study, the associations of character strengths with the DASS-21, GHQ-12 and SEC were examined, in terms of both second-order and single character strengths, by means of a series of linear regression models. This study focuses on the protective role of character strengths in sustaining mental health and self-efficacy during lockdown.
    keywords: character; covid-19; distress; efficacy; et al; factor; health; self; strengths; study
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        item: #7591 of 7819
          id: cord-353592-gsvobusu
      author: Luceño-Moreno, Lourdes
       title: Symptoms of Posttraumatic Stress, Anxiety, Depression, Levels of Resilience and Burnout in Spanish Health Personnel during the COVID-19 Pandemic
        date: 2020-07-30
       words: 7614
      flesch: 40
     summary: The protective variables of suffering posttraumatic stress symptoms are being a man, having a doctor's degree, living with a partner (not married), being a doctor or working in another position (a category made up mainly of pharmacists and psychologists), having protective equipment at work, not being concerned about infecting the people with whom they live and not living alone. The profile of a health worker with greater posttraumatic stress symptoms would be a person who works in the Autonomous Community of Madrid, in a hospital, is a woman, is concerned that a person he/she lives with may be infected, and thinks that he/she is very likely to be infected.
    keywords: anxiety; burnout; covid-19; depression; health; resilience; stress; study; symptoms; variables; workers
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        item: #7592 of 7819
          id: cord-353594-z1vxamvp
      author: Gagiannis, Daniel
       title: Clinical, Serological, and Histopathological Similarities Between Severe COVID-19 and Acute Exacerbation of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)
        date: 2020-10-02
       words: 5017
      flesch: 34
     summary: ANA titers ≥1:320 and/or positive ENA immunoblots were detected in 11/13 (84.6%) COVID-19 patients with ARDS, in 1/9 (11.1%) COVID-19 patients without ARDS (p = 0.002) and in 4/10 (40%) patients with non-COVID-19-associated pneumonias (p = 0.039). Our findings indicate that autoimmune mechanisms determine both clinical course and long-term sequelae after SARS-CoV-2 infection, and the presence of autoantibodies might predict adverse clinical course in COVID-19 patients.
    keywords: ana; anti; ards; autoantibodies; cases; cov-2; covid-19; disease; lung; patients; pneumonia; sars; table
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        item: #7593 of 7819
          id: cord-353599-cw29edwr
      author: Kelleni, Mina T.
       title: Early use of Non-steroidal anti-inflammatory drugs in COVID-19 might reverse pathogenesis, prevent complications and improve clinical outcomes
        date: 2020-11-04
       words: 2617
      flesch: 22
     summary: In this manuscript, we present a novel theory to explain the pathogenesis of COVID-19; lymphocyte distraction theory upon which the author has used, in a preprinted protocol, non-steroidal anti-inflammatory drugs (NSAIDs); diclofenac potassium, ibuprofen and ketoprofen, successfully to treat COVID-19 patients. Furthermore, we agree with a recommendation that glucocorticoids should not be used routinely for COVID-19 patients and suggested to be beneficial only for patients with late acute respiratory distress syndrome.
    keywords: covid-19; ibuprofen; lymphopenia; patients; sars
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        item: #7594 of 7819
          id: cord-353615-9aj5yxkd
      author: Colaneri, Marta
       title: Running out of bullets: the challenging management of acute hepatitis and SARS‐COV‐2 from the SMatteo COvid19 Registry (SMACORE)
        date: 2020-07-17
       words: 1605
      flesch: 37
     summary: Despite the lack of treatment guidelines and controlled human trials, HP has been used with efficacy to reduce IL-6 levels in septic patients and has been also proposed to mitigate disease progression in COVID-19 patients (17) . Specifically, the increase in liver enzymes in COVID-19 patients has been reported worldwide (6, 7) but the prevalence of liver injury and the associated clinical features of these patients are currently scarce (8) .
    keywords: acute; covid-19; hepatitis; liver; patients
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        item: #7595 of 7819
          id: cord-353618-r7skw6rf
      author: Papa, Alfonso
       title: Images in Practice: Painful Cutaneous Vasculitis in a SARS-Cov-2 IgG-Positive Child
        date: 2020-05-21
       words: 917
      flesch: 48
     summary: In a study carried out in China involving more than 44,000 cases of COVID-19, 0.9% of patients were between 0 and 10 years of age and 1.2% ranged in age from 10 to 19 years [1] . During the pandemic period in Italy, we observed more than ten pediatric patients who tested IgG positive for Sars-CoV-2 with painful vasculitic skin lesions on the feet that required modest pain relief therapy.
    keywords: cov-2; covid-19; sars
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        item: #7596 of 7819
          id: cord-353621-t5tev985
      author: Gallina, Pasquale
       title: Covid-19: Decisions to offer interventions with limited availability should be decided based on chance of recovery.
        date: 2020-05-21
       words: 316
      flesch: 32
     summary: COVID-19 in Italy: ageism and decision 89 making in a pandemic Nursing homes or besieged castles: 91 COVID-19 in northern Italy Universal 93 do-not-resuscitate orders, social worth, and life-years: opposing 94 discriminatory approaches to the allocation of resources during the 95 COVID-19 pandemic and other health system satastrophes Fair allocation of scarce 98 medical resources in the time of Covid-19 Clinical ethics 101 recommendations for the allocation of intensive care treatments in 102 exceptional, resource-limited circumstances: the Italian 103 perspective during the COVID-19 epidemic. Crit Care SIAARTI 106 recommendations for the allocation of intensive care treatments in 107 exceptional, resource-limited circumstances A Framework for Rationing Ventilators and 110 Critical Care Beds During the COVID-19 Pandemic An Introduction to the Principles of Morals and 113 Legislation
    keywords: covid-19
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        item: #7597 of 7819
          id: cord-353628-f6ew980g
      author: Zayet, Souheil
       title: Encephalopathy in patients with COVID‐19: ‘Causality or coincidence?’
        date: 2020-05-19
       words: 1527
      flesch: 46
     summary: Underestimated damage to nervous system The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China The neuroinvasive potential of SARS-CoV-2 may play a role in the respiratory failure of COVID-19 patients An alteration of the dopamine synthetic pathway is possibly involved in the pathophysiology of COVID-19 Identification of viruses in patients with postviral olfactory dysfunction Coronavirus disease 2019: new things to know On admission All authors declare no competing interests. key: cord-353628-f6ew980g authors: Zayet, Souheil; Ben Abdallah, Yousri; Royer, Pierre‐Yves; Toko‐Tchiundzie, Lynda; Gendrin, Vincent; Klopfenstein, Timothee title: Encephalopathy in patients with COVID‐19: ‘Causality or coincidence?’ date: 2020-05-19 journal: J Med Virol DOI: 10.1002/jmv.26027 sha: doc_id: 353628 cord_uid: f6ew980g The main tropism of the novel coronavirus disease 2019 (COVID‐19) is respiratory.
    keywords: cov-2; covid-19; march; patients; sars
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        item: #7598 of 7819
          id: cord-353648-rl9dts7l
      author: Kim, Hyun Joo
       title: Guidelines for the control and prevention of coronavirus disease (COVID-19) transmission in surgical and anesthetic settings
        date: 2020-05-12
       words: 1554
      flesch: 44
     summary: mid= a20507020000&bid= 0019 &act= view&list_no= 366579 FAQ on anesthesia machine use, protection, and decontamination during the COVID-19 pandemic No potential conflict of interest relevant to this article was reported. ③ Draeger • Refer to the link and attached file for the protocols to disassemble, clean, disinfect, and reassemble different types of anesthesia machine (Attachment 4.
    keywords: anesthesia; cleaning; filter; patient
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        item: #7599 of 7819
          id: cord-353659-wtacr6qj
      author: Almutairi, Nawaf
       title: Coronavirus Disease‐2019 with Dermatologic Manifestations and Implications: An Unfolding Conundrum
        date: 2020-05-09
       words: 1029
      flesch: 39
     summary: As another measure to prevent people from being hospitalized, it might be wise to actively discourage health care workers at high-risk, no matter how well-meaning, from being present at health care facilities, given both direct and fomite COVID-19 spread. As a nosocomial infection for hospital and nursing home patients and health care workers, it represents an extraordinary challenge.
    keywords: coronavirus; covid-19; health; patients
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        item: #7600 of 7819
          id: cord-353690-m79zl7ka
      author: Balmford, Andrew
       title: COVID-19: Analogues and lessons for tackling the extinction and climate crises
        date: 2020-06-28
       words: 1316
      flesch: 41
     summary: Likewise, delaying action on climate change such that the world experiences +2.0 o C rather than +1.5 o C warming will expose an estimated 62-457M more of the world's poorest people to multisector climate risks [8] . An IPCC Special Report on the impacts of global warming of 1.5°C above pre-industrial levels and related global greenhouse gas emission pathways, in the context of strengthening the global response to the threat of climate change, sustainable development, and efforts to eradicate poverty Acting fast helps avoid extinction COVID-19 data Coronavirus Government Response Tracker Rolling updates on coronavirus disease (COVID-19) GINI index (World Bank estimate) Urban population (% of total population) Household income and housing-cost statistics: Year ended
    keywords: climate; covid; deaths; extinction
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        item: #7601 of 7819
          id: cord-353697-ocxextfj
      author: Santana, Monique Freire
       title: Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management
        date: 2020-07-03
       words: 1891
      flesch: 35
     summary: COVID-19 is characterized by asymptomatic and/or mild flulike symptoms; however, about 20% of patients may progress to pneumonia and sepsis, thus requiring intensive support 1, . Patients with acute respiratory distress syndrome due to viral infections, such as SARS-CoV-2, are prone to secondary complications, including aspergillosis 2 .
    keywords: aspergillosis; aspergillus; covid-19; disease; infection; ipa; patient
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        item: #7602 of 7819
          id: cord-353698-gj8sx3zy
      author: Bibiano-Guillen, C.
       title: Adapted Diving Mask (ADM) device as respiratory support with oxygen output during COVID-19 pandemic
        date: 2020-10-28
       words: 3323
      flesch: 47
     summary: This prevents exposure to other patients and healthcare professionals [29, 32, 33] . To assess patient improvement, we used the following variables: The medical records of patients were analyzed by the research team of the Emergency Department, Hospital Universitario Infanta Leonor, Madrid.
    keywords: adm; covid-19; mask; oxygen; patients; saturation; support; use
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        item: #7603 of 7819
          id: cord-353717-jjd90fyh
      author: Singhavi, Ravi
       title: A Case of Hemolytic Anemia With Acute Myocarditis and Cardiogenic Shock: A Rare Presentation of COVID-19
        date: 2020-09-25
       words: 1463
      flesch: 37
     summary: In the context of cardiac involvement, acute myocarditis has become one of the unexplored areas in COVID-19 patients, which could influence the long-term outcomes. In this report, we presented a case of a COVID-19 patient who developed acute myocarditis and severe acute hemolytic anemia, as evident from peripheral blood smear showing schistocytes (fragmented RBCs) in peripheral smear with acute severe anemia along with elevated LDH, which is also a surrogate marker for hemolysis.
    keywords: acute; anemia; covid-19; myocarditis; patient
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        item: #7604 of 7819
          id: cord-353735-d81ujjxv
      author: Li, Jiannan
       title: The Episode of National Lockdown in the Pandemic: Air Traffic Restriction as the Control Strategy and Its Impact on Existing Cases and Recovery Rate of Novel Coronavirus Disease in Megacities of China
        date: 2020-08-12
       words: 1907
      flesch: 45
     summary: The effectiveness of air traffic restriction in containing the spread of infectious diseases is full of controversy in prior literature. In January 2020, the Civil Aviation Administration of China (CAAC) announced air traffic restriction in response to the coronavirus disease (COVID-19) pandemic.
    keywords: air; air traffic; restriction; traffic; traffic restriction
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        item: #7605 of 7819
          id: cord-353749-2vlc11rx
      author: Stricker, Raphael B
       title: Flattening the Risk: Pre-Exposure Prophylaxis for COVID-19
        date: 2020-10-19
       words: 3092
      flesch: 40
     summary: Protecting frontline health care workers from COVID-19 with hydroxychloroquine pre-exposure prophylaxis: a structured summary of a study protocol for a randomised placebo-controlled multisite trial in Toronto vitamin C, vitamin D, and zinc for the prevention of COVID-19 infection (HELPCOVID-19) Hydroxychloroquine in the COVID-19 pandemic era: in pursuit of a rational use for prophylaxis of SARS-CoV-2 infection Efficacy and safety of hydroxychloroquine vs placebo for preexposure SARS-CoV-2 prophylaxis among health care workers: A randomized clinical trial Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial Beyond the randomized controlled trial: a review of alternatives in mHealth clinical trial methods Effect of a US National Institutes of Health programme of clinical trials on public health and costs Characteristics and strength of evidence of COVID-19 studies registered on ClinicalTrials.gov COVID-19: real-time dissemination of scientific information to fight a public health emergency of international concern Mefloquine at the crossroads? [31] Malaria prophylaxis with HCQ may contribute in part to the reportedly low rate of COVID-19 infection seen so far in sub-Saharan Africa.
    keywords: cov-2; covid-19; hcq; infection; prophylaxis; risk; sars; treatment
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        item: #7606 of 7819
          id: cord-353756-lm2qs6ev
      author: Massey, Paul R.
       title: Going viral: A brief history of Chilblain-like skin lesions (“COVID toes”) amidst the COVID-19 pandemic
        date: 2020-05-23
       words: 1502
      flesch: 39
     summary: Shortly after this index report, images of similar acral lesions in the feet of children with suspected COVID-19 were circulated on Amici DermPed, an Italian pediatric dermatology forum. A French observational study Did Whatsapp((R)) reveal a new cutaneous COVID-19 manifestation? Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases Chilblain-like lesions: a case series of 41 patients during the COVID-19 pandemic Chilblain-like lesions on feet and hands during the COVID-19 Pandemic Chilblain-like lesions during COVID-19 epidemic: a preliminary study on 63 patients Acute acro-ischemia in the child at the time of COVID-19 (Monday's case)
    keywords: chilblain; covid-19; lesions; patients
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        item: #7607 of 7819
          id: cord-353824-0oyvia6d
      author: Farooque, Umar
       title: Coronavirus Disease 2019-Related Acute Ischemic Stroke: A Case Report
        date: 2020-09-08
       words: 1880
      flesch: 48
     summary: The possibility as to whether anticoagulant or antiplatelet agents may be superior in stroke patients with COVID-19 requires further consideration. Negative pressure carrier isolators can be used to isolate COVID-19 patients during neurovascular imaging.
    keywords: acute; covid-19; infection; patients; risk; stroke
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        item: #7608 of 7819
          id: cord-353833-woz5f3gh
      author: Feldman, Sarah
       title: How the Coronavirus Disease-2019 May Improve Care: Rethinking Cervical Cancer Prevention
        date: 2020-07-01
       words: 1643
      flesch: 43
     summary: We use cervical cancer screening and prevention as an example of how we can use some “lessons learned” from the pandemic to prevent “collateral losses,” such as an increase in cancers. COVID-2019–related health-system changes, like the more rapid evaluation of diagnostic tests and vaccines, the transition to compensated virtual care for most counseling and education visits, and broadened access to home services, offer potential benefits to the delivery of cervical cancer screening and prevention.
    keywords: cancer; care; patients; screening
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        item: #7609 of 7819
          id: cord-353840-yb6qi4rg
      author: Miki, Kosuke
       title: Association between cardiovascular manifestation and COVID‐19
        date: 2020-07-15
       words: 262
      flesch: 40
     summary: key: cord-353840-yb6qi4rg authors: Miki, Kosuke; Imamura, Teruhiko title: Association between cardiovascular manifestation and COVID‐19 date: 2020-07-15 journal: Clin Cardiol DOI: 10.1002/clc.23423 sha: doc_id: 353840 cord_uid: yb6qi4rg nan To the editor, Cardiovascular manifestation is receiving great concern as both cause and result of coronavirus disease 2019 (COVID-19). Chen et al systemically observed the association between COVID-19 and cardiovascular status including myocardial injury, blood pressure, and arrhythmia.
    keywords: covid-19
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        item: #7610 of 7819
          id: cord-353844-yaueoq62
      author: Bachanova, Veronika
       title: Chimeric Antigen Receptor T Cell Therapy During the COVID-19 Pandemic
        date: 2020-04-14
       words: 6374
      flesch: 32
     summary: Chimeric antigen receptor (CAR) T cell therapy represents a paradigm shift in the management of pediatric B-cell acute lymphoblastic leukemia (ALL) and adult B-cell non-Hodgkin lymphomas (NHL) These recommendations were carefully formulated with the understanding that resource allocation is of the utmost importance, and that the decision to proceed with CAR T cell therapy will require extensive discussion of potential risks and benefits.
    keywords: car; car t; care; cell; cell therapy; covid-19; crs; pandemic; patients; resources; t cell; therapy; tocilizumab; treatment
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        item: #7611 of 7819
          id: cord-353854-hbrk4tp5
      author: Agosti, Edoardo
       title: Impact of COVID-19 outbreak on spinal pathology: single center first impression
        date: 2020-05-05
       words: 676
      flesch: 39
     summary: This explains the relative increase in the number of spinal trauma patients hospitalized and treated surgically in our center. The drop in hospitalizations for non-traumatic spinal pathology can find two possible explanations: (1) patient tendency to stay away from hospitals, seen as places at high infection risk, and prefer a conservative treatment (i.e. analgesic therapy and rest)
    keywords: covid-19; spinal
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        item: #7612 of 7819
          id: cord-353862-7xe3fvd5
      author: Li, Na
       title: Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study
        date: 2020-03-30
       words: 3518
      flesch: 49
     summary: However, previous studies argued that false negative cases might be common for COVID-19 infection cases due to low virus titers, sampling at late stage of illness, and This rate was higher than in suspected patients (16.7%) and in two control groups (~5%) of our study, but lower than the rate of 44% in confirmed COVID-19 pneumonia patients reported by Chen et al.
    keywords: cases; covid-19; delivery; patients; pneumonia; sars; women
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        item: #7613 of 7819
          id: cord-353872-hajtlw9k
      author: Cox, Shereen
       title: To dispense or not to dispense: Lessons to be learnt from ethical challenges faced by pharmacists in the COVID‐19 pandemic
        date: 2020-08-25
       words: 1824
      flesch: 46
     summary: In their recommendation to address moral distress among community pharmacists, Astbury and Gallagher, suggest a systemic approach to further enquiry and evaluation that seeks to promote the competency and confidence of pharmacists as moral agents whilst addressing the structural barriers to morally congruent practice. This paper seeks to 1) highlight some of the ethical challenges of dispensing hydroxychloroquine by pharmacists during the COVID‐19 pandemic, 2) identify some of the responses to these issues from various regulatory authorities in the USA, and 3) recommend approaches to assist pharmacists in their decision‐making process, especially in LMICs.
    keywords: covid-19; dispense; hydroxychloroquine; patients; pharmacists
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        item: #7614 of 7819
          id: cord-353876-pb4of7s9
      author: Fortaleza, Carlos Magno Castelo Branco
       title: Evidence, rationality, and ignorance: Agnotological issues in COVID-19 science
        date: 2020-09-21
       words: 3263
      flesch: 38
     summary: This serves as a fertile breeding ground for agnotological strategies, whereby scientific studies are deliberately or unintentionally designed to create distractions or draw conclusions that are not supported by research findings. Researchers, public health authorities, and healthcare workers should be equipped to identify such agnotological strategies, distinguish them from scientific fraud, and avoid drawing misleading inferences based on an irrational adherence to hypotheses and a lack of criticism of implausible results.
    keywords: covid-19; evidence; findings; ignorance; research; science; strategies; studies
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        item: #7615 of 7819
          id: cord-353887-f4yd7guj
      author: Tang, Yujun
       title: Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies
        date: 2020-07-10
       words: 8554
      flesch: 36
     summary: medRxiv Virus-host interactome and proteomic survey of PMBCs from COVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis Tocilizumab, an anti-IL6 receptor antibody, to treat Covid-19-related respiratory failure: a case report First case of COVID-19 in a patient with multiple myeloma successfully treated with tocilizumab A case of novel coronavirus disease 19 in a chronic hemodialysis patient presenting with gastroenteritis and developing severe pulmonary disease Dramatic improvement after Tocilizumab of a severe COVID-19 in a child with sickle cell disease and acute chest syndrome Tocilizumab treatment in COVID-19: a single center experience Effective treatment of severe COVID-19 patients with tocilizumab Pilot prospective open, single-arm multicentre study on off-label use of tocilizumab in severe patients with COVID-19 Use of tocilizumab for COVID-19 infection-induced cytokine release syndrome: a cautionary case report EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2019 update Safety of synthetic and biological DMARDs: a systematic literature review informing the 2019 update of the EULAR recommendations for the management of rheumatoid arthritis Negative regulation of nuclear factor-kappaB activation and function by glucocorticoids Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: evidence for post-transcriptional regulation Kelley's Textbook of Rheumatology E-Book The effect of corticosteroid treatment on patients with coronavirus infection: a systematic review and meta-analysis Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province Corticosteroid treatment of patients with coronavirus disease 2019 ( Besides, corticosteroids, programmed cell death protein (PD)-1/PD-L1 checkpoint inhibition, cytokine-adsorption devices, intravenous immunoglobulin, and antimalarial agents could be potentially useful and reliable approaches to counteract cytokine storm in COVID-19 patients.
    keywords: activation; artemisinin; artesunate; cells; coronavirus; covid-19; cytokines; disease; il-6; infection; inflammatory; levels; macrophages; patients; sars; storm; study; syndrome; treatment
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        item: #7616 of 7819
          id: cord-353890-dzauzjm7
      author: Guzzi, Pietro Hiram
       title: Spatio-Temporal Resource Mapping for Intensive Care Units at Regional Level for COVID-19 Emergency in Italy
        date: 2020-05-12
       words: 2162
      flesch: 52
     summary: By using infections vs ICU beds trend, we were able to calculate the number of infections for some time point in the future and derive the number of predicted ICU beds which will be occupied. COVID-19 patients management requires availability of sufficiently large number of Intensive Care Units (ICUs) beds.
    keywords: beds; covid-19; icu; icus; patients
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        item: #7617 of 7819
          id: cord-353904-dieaqxmi
      author: Davies, M.
       title: Remdesivir in treatment of COVID-19: A systematic benefit-risk assessment
        date: 2020-05-12
       words: 4060
      flesch: 43
     summary: Risk data were only available from one trial. Risk data were only available from the Wang et al trial, which reported fewer serious adverse events in patients taking remdesivir (18%) comparted to the placebo group (26%), however more patients in the remdesivir group discontinued treatment as a result of an adverse event compared to those patients receiving placebo (12% vs 5%).
    keywords: benefit; covid-19; data; patients; remdesivir; risk; trial
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        item: #7618 of 7819
          id: cord-353939-vz2bpkyk
      author: Ranger, Amita
       title: Interleukin‐6 Blockade Treatment for COVID‐19 associated Cytokine Release Syndrome in a Patient with Poorly Controlled Chronic Myeloid Leukaemia
        date: 2020-06-01
       words: 696
      flesch: 33
     summary: Critical care beds are a limited resource and patients with haematological disorders are considered to have poor outcomes following admission to intensive care units (ICU). Therapies such as this have the potential to change the outcome of severe COVID-19 infection and prevent ICU admission, particularly in patients believed to be unsuitable for critical care or where there is a great demand on critical care resources.
    keywords: covid-19; patients; tocilizumab
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        item: #7619 of 7819
          id: cord-353942-l9kjnrky
      author: None
       title: Essais cliniques au cours de la pandémie COVID-19 : cibles thérapeutiques, exigences méthodologiques, impératifs éthiques
        date: 2020-06-09
       words: 3838
      flesch: 51
     summary: Enfin la DGS et l'ANSM ont publié des recommandations destinées à la conduite des recherches dans le contexte de la pandémie L'expérience actuelle montre cependant le danger d'une approche purement empathique ou compassionnelle, car elle retarde la réponse à la question de l'efficacité des médicaments testés.
    keywords: aux; covid-19; dans; des; essais; est; les; ont; par; pas; patients; pour; que; qui; sont; sur; thérapeutiques; une
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        item: #7620 of 7819
          id: cord-353956-gjv5cg3k
      author: Bali, Rishi Kumar
       title: Maxillofacial surgery and COVID-19, The Pandemic !!
        date: 2020-04-11
       words: 1136
      flesch: 43
     summary: The collection, segregation, and transport of infectious waste from COVID-19 patients should be done under the guidance of the Infection Control/ Biomedical Waste Management Officer of the institute. As with most respiratory infections, droplets are the main source of transmission from COVID-19 patients.
    keywords: covid-19; infection; patients; use
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        item: #7621 of 7819
          id: cord-353976-gns5omyb
      author: Kafieh, Rahele
       title: COVID-19 in Iran: A Deeper Look Into The Future
        date: 2020-04-27
       words: 4525
      flesch: 53
     summary: In this work, we propose to show the performance of different deep learning (DL) and machine learning (ML) models for COVID-19 data prediction for above mentioned dataset. To have a successful prediction using deep learning based models, it is essential to have a large-scale dataset.
    keywords: cases; china; covid-19; data; epidemic; model; number; prediction; preprint
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        item: #7622 of 7819
          id: cord-353996-slnyun4l
      author: Baumgartner, M. T.
       title: Social distancing and movement constraint as the most likely factors for COVID-19 outbreak control in Brazil
        date: 2020-05-08
       words: 6879
      flesch: 45
     summary: We downloaded temperature and precipitation values between February and April, which coincided with the time series of COVID-19 cases in Brazil and with the late summer season of the Southern Hemisphere, matching the world outbreak of the virus. For inference, we then plotted the log-transformed total number of confirmed cases against the standardized slopes of the models, which portrays the state-dependent context of growth in COVID-19 cases.
    keywords: brazil; cases; cities; coronavirus; covid-19; distancing; license; medrxiv; people; preprint; spread
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        item: #7623 of 7819
          id: cord-354009-1ek4s8oe
      author: Wang, Yun
       title: Spatiotemporal Characteristics of COVID-19 Epidemic in the United States
        date: 2020-07-08
       words: 3145
      flesch: 51
     summary: We obtained county-based counts of COVID-19 cases confirmed in the United States from January 22 to May 13, 2020 (N=1,386,050). We obtained the counts of COVID-19 cases diagnosed from January 22 to May 13, 2020 in the United States from the USAFacts, a not-for-profit initiative standardizing and providing the government record-based data publicly available.
    keywords: areas; cases; counties; covid-19; epi; incidence
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        item: #7624 of 7819
          id: cord-354031-j4qlvm60
      author: Rodríguez-Pérez, Celia
       title: Changes in Dietary Behaviours during the COVID-19 Outbreak Confinement in the Spanish COVIDiet Study
        date: 2020-06-10
       words: 6915
      flesch: 46
     summary: Indeed, men showed a stronger association between the change in adherence to MedDiet and these variables than women (e.g., OR for the association between increase of olive oil intake and MedDiet adherence change = 8.00 in men and 3.71 in women) (Supplemental Table S6 ). Given the linearity of the association between MedDiet adherence change and duration of confinement (Supplementary Figure S1A) , it was estimated that the odds of change in the adherence increased by 8% per 5 days increase of confinement (95% CI: 1.01-1.17).
    keywords: adherence; change; confinement; covid-19; food; intake; meddiet; meddiet adherence; participants; spanish; study
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        item: #7625 of 7819
          id: cord-354039-2fwy9z19
      author: Kelly, Brendan D.
       title: Mental health, mental capacity, ethics and the law in the context of Covid-19 (coronavirus)
        date: 2020-10-01
       words: 572
      flesch: 38
     summary: This special issue of the International Journal of Law and Psychiatry explores mental health law, mental capacity law, and medical and legal ethics in the context of Covid-19. health law, mental capacity law, and medical and legal ethics.
    keywords: covid-19; law
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        item: #7626 of 7819
          id: cord-354073-tn76muv6
      author: Jen, Tung-Hui
       title: Geographic risk assessment of COVID-19 transmission using recent data: An observational study
        date: 2020-06-12
       words: 3976
      flesch: 55
     summary: We downloaded daily COVID-19 outbreak numbers for countries/regions from the GitHub website, which contains information on confirmed cases in more than 30 Chinese locations and other countries/regions. Travel information required for knowledge of COVID- 19 risk In an influenza pandemic, the strength of the increase in confirmed cases is a proxy for epidemic size and disease transmissibility.
    keywords: cases; cfr; countries; covid-19; outbreak; rasch; regions; risk; transmission
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        item: #7627 of 7819
          id: cord-354087-wmk0z894
      author: Parker, Carmen Black
       title: Differentiating Domains of Involuntary Containment for Persons with Severe Psychiatric Impairment and COVID-19
        date: 2020-06-18
       words: 743
      flesch: 17
     summary: Like Mr. A, involuntary psychiatric hospitalization is intended for individuals, with or without COVID-19, experiencing acute deviations from psychiatric baseline that may reasonably benefit from emergency hospitalization. Thus, involuntary psychiatric hospitalization may indirectly alleviate behavioral difficulties adhering with COVID-19 safeguards, thereby circuitously decreasing harm (infection) to others.
    keywords: covid-19; psychiatric
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        item: #7628 of 7819
          id: cord-354096-x2skguz8
      author: Ray, Pradipta R.
       title: A pharmacological interactome between COVID-19 patient samples and human sensory neurons reveals potential drivers of neurogenic pulmonary dysfunction
        date: 2020-06-01
       words: 6357
      flesch: 32
     summary: Mouse bulk RNA-sequencing datasets were obtained from sorted neuronal cell pools from the DRG (Liang et al., 2019) and whole tissue RNA-seq from the JNC complex before and after LPS injury (Kaelberer et al., 2020) . Two other metrics help rank neuronal genes: gene expression levels in sorted mouse DRG neuron datasets (Liang et al., 2019) and in mouse DRG neuron scRNA-seq datasets (Usoskin et al., 2015) , and degree of differential expression (log fold change) in LPS based injury models of mouse airway-innervating neurons (Kaelberer et al., 2020)
    keywords: balf; cell; covid-19; data; et al; gene; interactions; lung; neurons; patients; potential; receptor; rna; samples
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        item: #7629 of 7819
          id: cord-354103-4dldgqzf
      author: Grubic, Andrew D
       title: COVID-19 outbreak and surgical practice: The rationale for suspending non-urgent surgeries and role of testing modalities
        date: 2020-06-27
       words: 4875
      flesch: 44
     summary: ACE2 receptors are also located in the enterocytes of the small intestine which is considered to be an explanation for digestive symptoms in COVID-19 patients [13, 14] . Several studies have highlighted the presence of virus in the feces of COVID-19 patients, and now fecal-oral transmission has also been proposed as a mechanism of spread [8, 9] , which may profoundly impact underdeveloped countries.
    keywords: care; cases; coronavirus; cov-2; covid-19; disease; pandemic; patients; pcr; sars; transmission
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        item: #7630 of 7819
          id: cord-354113-j8odxs1h
      author: Miao, Congliang
       title: A comparative multi-centre study on the clinical and imaging features of comfirmed and uncomfirmed patients with COVID-19
        date: 2020-03-24
       words: 3132
      flesch: 48
     summary: Our aim was to compare clinical and imaging characteristics of COVID-19 patients outside Hubei province between confirmed and unconfirmed group. Compared with unconfirmed patients, confirmed patients had significantly higher proportion of dry cough, leucopenia, lymphopenia and accelerated ESR (P<0.05); but not with alanine aminotransferase, aspartate aminotransferase, D-dimer, lactic dehydrogenase, and myoglobin (P>0.05).
    keywords: covid-19; group; medrxiv; patients; peer; preprint; review
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        item: #7631 of 7819
          id: cord-354129-7ayqkeb8
      author: Filetti, Sebastiano
       title: A journey through and beyond a “perfect storm”: the COVID-19 pandemic
        date: 2020-05-12
       words: 678
      flesch: 44
     summary: As a result, many surgical procedures for thyroid cancer have been postponed, along with biopsies of suspicious nodules and radioiodine therapy, and diabetes and other endocrine or metabolic disorders are being managed without the regular follow-up visits previously considered essential. We have already received numerous contributions, and our editors and reviewers are busily reviewing them all.
    keywords: covid-19; endocrine
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        item: #7632 of 7819
          id: cord-354133-11b0d499
      author: Thomas, B. S.
       title: Estimating the Case Fatality Ratio for COVID-19 using a Time-Shifted Distribution Analysis
        date: 2020-10-27
       words: 7508
      flesch: 49
     summary: However, the closeness of the match reflects a much simpler apparent relationship than that suggested or assumed by conventional analyses, which relate deaths and cases using statistical parametric models that incorporate a broad distribution of expected times between diagnosis (or onset) and death, usually generated from case study data (e.g. [15] ). The mean delay between onset of symptoms and death has been estimated at 12-22 days using case data [2, 5, 7, 10, 12, 16] , but there are also delays between onset of symptoms and testing, between testing and reporting of results, and in reporting of deaths.
    keywords: case; cfr; data; delay; license; medrxiv preprint; preprint; review; time
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        item: #7633 of 7819
          id: cord-354134-gb2pf5kb
      author: Güemes-Villahoz, Noemi
       title: Conjunctivitis in COVID-19 patients: frequency and clinical presentation
        date: 2020-08-29
       words: 3465
      flesch: 38
     summary: However, in the analysis of conjunctivitis patients by clinical severity, there were statistically significant differences by sex (Table 4 ). key: cord-354134-gb2pf5kb authors: Güemes-Villahoz, Noemi; Burgos-Blasco, Barbara; García-Feijoó, Julián; Sáenz-Francés, Federico; Arriola-Villalobos, Pedro; Martinez-de-la-Casa, Jose María; Benítez-del-Castillo, Jose Manuel; Herrera de la Muela, María title: Conjunctivitis in COVID-19 patients: frequency and clinical presentation date: 2020-08-29 journal: Graefes Arch Clin Exp Ophthalmol DOI: 10.1007/s00417-020-04916-0 sha: doc_id: 354134 cord_uid: gb2pf5kb PURPOSE:
    keywords: conjunctivitis; covid-19; disease; patients; sars; study; symptoms
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        item: #7634 of 7819
          id: cord-354147-01dhp7nn
      author: Gonzalez, Rocío Maqueda
       title: Proctologic emergency consultation during COVID-19: comparative cross-sectional cohort study
        date: 2020-10-23
       words: 3212
      flesch: 33
     summary: key: cord-354147-01dhp7nn authors: Gonzalez, Rocío Maqueda; Santacruz, Carlos Cerdán; Septiem, Javier García; Terés, Lara Blanco; González, Jose María Lopesino; Jiménez, Guillermo Fernández; Martín-Pérez, Elena title: Proctologic emergency consultation during COVID-19: comparative cross-sectional cohort study date: 2020-10-23 journal: Cir Esp DOI: 10.1016/j.ciresp.2020.10.002 sha: doc_id: 354147 cord_uid: 01dhp7nn Introduction: Conclusion: There was a decrease of a 56% in proctologic emergency consultation, however, the need for surgery was twice more frequent during the study period.
    keywords: consultation; covid-19; emergency; health; pandemic; patients; study
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        item: #7635 of 7819
          id: cord-354160-sca9bgeq
      author: Al-Tawfiq, Jaffar A.
       title: Changes in Healthcare managing COVID and non-COVID-19 patients during the pandemic: Striking the balance
        date: 2020-08-13
       words: 1749
      flesch: 38
     summary: There are multiple factors contributing to the apparent reduced utilization of healthcare services by to non-COVID-19 patients. Furthermore, in order to properly care for non-COVID-19 patients, it had been suggested that there should be separate hospitals for those with COVID-19 and those without COVID- 19
    keywords: covid-19; healthcare; non; pandemic; patients
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        item: #7636 of 7819
          id: cord-354164-tlmfn4bm
      author: Liao, Xuelian
       title: Critical Care for Severe COVID-19: A Population-based Study from a Province with Low Case-fatality Rate in China
        date: 2020-03-27
       words: 5022
      flesch: 53
     summary: Out of the 21 planned designated hospitals for severe cases, 18 received severe patients during the study period. Interpretation The multi-strategy management for severe COVID-19 patients included early identification and timely critical care, including appropriate respiratory support in particular.
    keywords: author; covid-19; funder; international; license; medrxiv; patients; preprint
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        item: #7637 of 7819
          id: cord-354168-omen8vvq
      author: Al Saleh, Abdullah S.
       title: Multiple Myeloma in the Time of COVID-19
        date: 2020-04-17
       words: 3955
      flesch: 52
     summary: key: cord-354168-omen8vvq authors: Al Saleh, Abdullah S.; Sher, Taimur; Gertz, Morie A. title: Multiple Myeloma in the Time of COVID-19 date: 2020-04-17 journal: Acta Haematol DOI: 10.1159/000507690 sha: doc_id: 354168 cord_uid: omen8vvq We provide our recommendations (not evidence based) for managing multiple myeloma patients during the pandemic of COVID-19. Lancet Oncol Multiple myeloma and infections: a population-based study on 9253 multiple myeloma patients Nadir lymphocytopenia as a risk factor of bloodstream infection during molecular targeting pharmacotherapy in multiple myeloma Pretreatment lymphopenia, poor performance status, and early courses of therapy are risk factors for severe bacterial infection in patients with multiple myeloma during treatment with bortezomib-based regimens Lymphocytopenia is associated with an increased risk of severe infections in patients with multiple myeloma treated with bortezomib-based regimens Immune parameters in multiple myeloma patients: influence of treatment and correlation with opportunistic infections Low frequency of CD3+CD4+CD161+ T cells correlates with the occurrence of infections in refractory/relapsed multiple myeloma patients receiving lenalidomide plus low-dose dexamethasone treatment Infection risk with immunomodulatory and proteasome inhibitor-based therapies across treatment phases for multiple myeloma: a systematic review and meta-analysis Decrease in CD4+ T-cell counts in patients with multiple myeloma treated with bortezomib Analysis of herpes zoster events among bortezomib-treated patients in the phase III APEX study Levofloxacin prophylaxis in patients with newly diagnosed myeloma (TEAMM): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial Clinical features of patients infected with 2019 novel coronavirus in Wuhan Risk stratification of smoldering multiple myeloma incorporating revised IMWG diagnostic criteria Lenalidomide plus dexamethasone for high-risk smoldering multiple myeloma Randomized trial of lenalidomide versus observation in smoldering multiple myeloma Revised international staging system for multiple myeloma: a report from International Myeloma Working Group get-your-household-ready-for-COVID-19.html?CDC_AA_ r e f V a l
    keywords: asct; covid-19; dexamethasone; lenalidomide; myeloma; patients; risk; therapy
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        item: #7638 of 7819
          id: cord-354180-6esn3t2b
      author: Tyndall, Mark
       title: Safer opioid distribution in response to the COVID-19 pandemic
        date: 2020-07-27
       words: 4227
      flesch: 51
     summary: It has become obvious to those who are most impacted by the overdose crisis that nothing short of providing access to safer opioid drugs will reduce overdoses (Fischer & Pang & Tyndall, 2019) . Drug overdose has always been a risk for people who relied on an unregulated street market for their drugs.
    keywords: covid-19; deaths; drugs; opioid; overdose; people; reduction; supply; use
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        item: #7639 of 7819
          id: cord-354204-23xkug85
      author: Smargiassi, Andrea
       title: Lung ultrasonography for early management of patients with respiratory symptoms during COVID-19 pandemic
        date: 2020-07-07
       words: 3445
      flesch: 29
     summary: A proposed algorithm to early manage pediatric patients with symptoms compatible with COVID-19, admitted to the pediatric emergency room Zhang J (2020) Characteristics of COVID-19 infection in Beijing Clinical progression of patients with COVID-19 in Shanghai Clinical features of patients infected with novel 2019 coronavirus in Wuhan CT features of SARS-CoV-2 pneumonia according to clinical presentation: a retrospective analysis of 120 consecutive patients from Wuhan city Chinese Critical Care Ultrasound Study Group (CCUSG) (2020) Findings of lung ultrasonography of novel corona virus pneumonia during the 2019-2020 epidemic Is there a role for lung ultrasound during the COVID-19 outbreak? Pulmonary pathology of early-phase 2019 novel coronavirus (COVID-19) pneumonia in two patients with lung cancer COVID-19: pneumonia, ARDS or something else? Microvascular COVID-19 lung vessels obstructive thromboinflammatory syndrome (MicroCLOTS): an atypical acute respiratory distress syndrome working hypothesis The role of ultrasound lung artifacts in the diagnosis of respiratory diseases Lung ultrasonography and vertical artifacts: the shape of air Artifactual lung ultrasonography: it is a matter of traps, order, and disorder On the physical basis of pulmonary sonographic interstitial syndrome Lung ultrasonography may provide an indirect estimation of lung porosity and airspace geometry Physical mechanisms providing clinical information from ultrasound lung images: hypotheses and early confirmations Determination of a potential quantitative measure of the state of the lung using lung ultrasound spectroscopy Proposal for international standardization of the use of lung ultrasound for COVID-19 patients; a simple, quantitative, reproducible method Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents Chest sonography: a useful tool to differentiate acute cardiogenic pulmonary edema from acute respiratory distress syndrome Thoracic ultrasound and SARS-COVID-19: a pictorial essay How to perform lung ultrasound in pregnant women with suspected COVID-19 infection Effectiveness of a 'fast lung ultrasound teaching program' for gynecologists/obstetricians dealing with pregnant women with suspicion of COVID-19 infection Clinical role of lung ultrasound for the diagnosis and monitoring of COVID-19 pneumonia in pregnant women The diagnosis of pneumonia in a pregnant woman with covid-19 using maternal lung ultrasound Acute respiratory distress syndrome in pregnancy Point-of-Care Lung Ultrasound findings in novel coronavirus disease-19 pnemoniae: a case report and potential applications during COVID-19 outbreak Is lung ultrasound useful for diagnosing pneumonia in children? In our experience in performing LUS in suspected COVID-19 patients, both pocket and wireless devices [17] than standard ultrasound machines can be used better if dedicated exclusively to COVID-19 patients to reduce healthcare operator/patients infection.
    keywords: covid-19; lung; lus; patients; pneumonia; tests
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        item: #7640 of 7819
          id: cord-354216-4khdcjed
      author: Sultan, Shahnaz
       title: AGA Institute Rapid Review of the GI and Liver Manifestations of COVID-19, Meta-Analysis of International Data, and Recommendations for the Consultative Management of Patients with COVID-19
        date: 2020-05-11
       words: 5643
      flesch: 38
     summary: Therefore, in high prevalence settings, among patients presenting with new onset diarrhea, monitoring for the development of COVID-19 symptoms and considering referring patients for COVIDtesting is reasonable especially if testing capacity is not limited. In a handful of studies, diarrhea and nausea preceded the development of other COVID-19 related symptoms.
    keywords: analysis; clinical; coronavirus; covid-19; data; diarrhea; disease; liver; patients; studies; symptoms
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        item: #7641 of 7819
          id: cord-354223-0ckpz0bx
      author: Yu, Pengming
       title: Early Rehabilitation for Critically Ill Patients With COVID-19: More Benefits Than Risks
        date: 2020-04-13
       words: 1664
      flesch: 31
     summary: The rehabilitation clinicians are concerned that there is no precedent for early rehabilitation treatment of COVID-19, a lack of experience in acute management of COVID-19 patients, and the absence of guidelines, recommendations, and expert consensus. The finding suggests that COVID-19 patients commonly had neurological symptoms manifested as acute stroke (6%), consciousness impairment (15%), and skeletal muscle injury (19%).
    keywords: covid-19; disease; patients; rehabilitation
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        item: #7642 of 7819
          id: cord-354232-tunpb48l
      author: Stall, N. M.
       title: For-profit nursing homes and the risk of COVID-19 outbreaks and resident deaths in Ontario, Canada
        date: 2020-05-27
       words: 3793
      flesch: 49
     summary: key: cord-354232-tunpb48l authors: Stall, N. M.; Jones, A.; Brown, K. A.; Rochon, P. A.; Costa, A. P. title: For-profit nursing homes and the risk of COVID-19 outbreaks and resident deaths in Ontario, Canada date: 2020-05-27 journal: nan DOI: 10.1101/2020.05.25.20112664 sha: doc_id: 354232 cord_uid: tunpb48l Background: Nursing homes have become the epicentre of the coronavirus disease 2019 (COVID-19) pandemic in Canada. Nursing homes have become the epicentre of the coronavirus disease 2019 (COVID- 19) pandemic in Canada, with residents of these care homes accounting for more than 80% of the country's deaths (1, 2) .
    keywords: care; covid-19; homes; license; nursing; preprint; profit
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        item: #7643 of 7819
          id: cord-354236-vn45rnve
      author: Allegrante, John P.
       title: Preventing COVID-19 and Its Sequela: “There Is No Magic Bullet . . . It's Just Behaviors”
        date: 2020-05-30
       words: 2019
      flesch: 27
     summary: When national, state and local policies are aligned with organizational goals in a conducive family/social environment, and the individual is motivated and receptive to behavioral change messages, COVID-19 protective behavior will be maximized. CNBC What recent history has taught us about responding to emerging infectious disease threats Using social and behavioural science to support COVID-19 pandemic response Ecological models of health behavior The lessons of the pandemic
    keywords: behaviors; covid-19; health; pandemic; public; science
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        item: #7644 of 7819
          id: cord-354247-erzak928
      author: Iain Pritchard, Roger
       title: Impact of Regulatory Changes on Pharmacist Delivered Telehealth During the COVID-19 Pandemic
        date: 2020-06-15
       words: 2341
      flesch: 36
     summary: Under this waiver, CMS authorized the delivery of Medicare telehealth services throughout the nation. With the expected expansion of Medicare telehealth appointments due to these changes, CMS also announced that the HHS office for Civil Rights would be exercising enforcement discretion and waive penalties for HIPAA violations against providers serving patients in good faith through everyday communication technology, which allows providers to use services such as FaceTime, Skype, and Zoom to complete Medicare telehealth services.
    keywords: changes; medicare; pharmacists; providers; services; telehealth
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        item: #7645 of 7819
          id: cord-354257-45bwzuqn
      author: Liu, Mengqi
       title: COVID-19 pneumonia: CT findings of 122 patients and differentiation from influenza pneumonia
        date: 2020-05-12
       words: 3291
      flesch: 47
     summary: Radiology Performance of radiologists in differentiating COVID-19 from viral pneumonia on chest CT CT findings in viral lower respiratory tract infections caused by parainfluenza virus, influenza virus and respiratory syncytial virus Evaluating the accuracy of different respiratory specimens in the laboratory diagnosis and monitoring the viral shedding of 2019-nCoV infections Sensitivity of chest CT for COVID-19: comparison to RT-PCR Relation between chest CT findings and clinical conditions of coronavirus disease (COVID-19) pneumonia: a multicenter study Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China Emerging coronavirus 2019-nCoV pneumonia CT imaging of the 2019 novel coronavirus (2019-nCoV) pneumonia. Among the COVID-19 group, a hundred and two patients (83%) had contact with individuals from Wuhan (traveled to/or lived in Wuhan, or were in contact with confirmed COVID-19 patients).
    keywords: covid-19; influenza; opacities; patients; pneumonia; thickening
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        item: #7646 of 7819
          id: cord-354261-gdvawnp6
      author: Gale, Chris
       title: National active surveillance to understand and inform neonatal care in COVID-19
        date: 2020-06-14
       words: 1628
      flesch: 39
     summary: There are three key ways that SARS-CoV-2 could affect neonates: 1. Vertical transmission of SARS-CoV-2 from mother to infant, which may lead to neonatal COVID-19. CoV-2 in the neonatal period, potentially leading to neonatal COVID-19; this may occur from family contacts or nosocomial transmission in healthcare settings, such as neonatal units.
    keywords: covid-19; data; neonatal; sars; surveillance
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        item: #7647 of 7819
          id: cord-354265-udt2spoe
      author: Gersh, Felice
       title: Menopause status and COVID-19
        date: 2020-09-23
       words: 582
      flesch: 32
     summary: (8) Given the potential for serious negative effects ensuing from a state of estradiol deficiency, heightened by the COVID-19 pandemic, not only should appropriate postmenopausal women be considered for hormone replacement therapy, but women being treated with aromatase inhibitors and estrogen receptor antagonists should be counseled on the risks and benefits of those drugs, personalized in each case, in light of the findings of this study. (7) The use of hormone replacement therapy gains further support from this excellent study.
    keywords: women
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        item: #7648 of 7819
          id: cord-354270-445lhfdc
      author: Chen, Rong-ning
       title: Mental health status and change in living rhythms among college students in China during the COVID-19 pandemic: A large-scale survey
        date: 2020-08-15
       words: 4424
      flesch: 44
     summary: A recent study on the prevalence of anxiety in Chinese college students suggested that the COVID-19-related stressors (included effects on daily-life, and academic delays) were positively associated with the level of anxiety symptoms, indicating that the mental health of college students could be affected by public health emergencies [24] . key: cord-354270-445lhfdc authors: Chen, Rong-ning; Liang, Shun-wei; Peng, Yang; Li, Xue-guo; Chen, Jian-bin; Tang, Si-yao; Zhao, Jing-bo title: Mental health status and change in living rhythms among college students in China during the COVID-19 pandemic: A large-scale survey date: 2020-08-15 journal: Journal of Psychosomatic Research DOI: 10.1016/j.jpsychores.2020.110219 sha: doc_id: 354270 cord_uid: 445lhfdc • 7.7% of college students showed depressive symptoms during the COVID-19 pandemic.
    keywords: college; covid-19; health; pandemic; students; study; symptoms
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        item: #7649 of 7819
          id: cord-354306-zbkgabl2
      author: Pennycook, Gordon
       title: Fighting COVID-19 Misinformation on Social Media: Experimental Evidence for a Scalable Accuracy-Nudge Intervention
        date: 2020-06-30
       words: 5998
      flesch: 44
     summary: In particular, CRT score was negatively correlated with belief in false headlines and uncorrelated with belief in true headlines, whereas CRT score was negatively correlated with sharing of both types of headlines (albeit more negatively correlated with sharing of false headlines compared with true headlines; for effect sizes, see Table 1 ). In particular, science knowledge was negatively correlated with belief in false headlines and positively correlated with belief in true headlines, whereas science knowledge was negatively correlated with sharing of false headlines and uncorrelated with sharing of true headlines (for effect sizes, see Table 1 ).
    keywords: accuracy; covid-19; discernment; headlines; media; news; participants; sharing; study
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        item: #7650 of 7819
          id: cord-354307-9uriite7
      author: Cal, Teresa Segura de la
       title: Unexpected favourable course of Coronavirus Disease 2019 in chronic thromboembolic pulmonary hypertension patients
        date: 2020-06-26
       words: 1315
      flesch: 36
     summary: f Dear Editor, Chronic thromboembolic pulmonary hypertension (CTEPH) results from obstruction of the pulmonary arterial bed by organized thrombus after acute or recurrent pulmonary embolism (PE). Chronic thromboembolic pulmonary hypertension (CTEPH): results from an international prospective registry Chronic thromboembolic pulmonary hypertension Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19)
    keywords: covid-19; cteph; patients; sars
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        item: #7651 of 7819
          id: cord-354308-ol8twpay
      author: Mardani,
       title: COVID-19 infection recurrence presented with meningoencephalitis
        date: 2020-07-23
       words: 1461
      flesch: 35
     summary: key: cord-354308-ol8twpay authors: Mardani,; Nadji, Seyed Alireza; Aghazadeh Sarhangipor, Kouros; Sharifi-Razavi, Athena; Baziborun, Mana title: COVID-19 infection recurrence presented with meningoencephalitis date: 2020-07-23 journal: New Microbes New Infect DOI: 10.1016/j.nmni.2020.100732 sha: doc_id: 354308 cord_uid: ol8twpay Results for COVID-19 RT-PCR from her cerebrospinal fluid, nasopharyngeal and tracheal aspiration specimens became positive again whereas, negative COVID-19 serum antibodies.
    keywords: covid-19; csf; patients; pcr; sars
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        item: #7652 of 7819
          id: cord-354330-pud2rqxk
      author: Pirzada, Abdul Rouf
       title: Management of Aerosol during Noninvasive Ventilation for Patients with Sleep-Disordered Breathing: Important Messages during the COVID-19 Pandemic
        date: 2020-06-17
       words: 3208
      flesch: 43
     summary: However, it is recommended to suspend sleep studies and NIV titration trials for subjects who report to having recent travel or residential history in a high epidemic area [21] , contact history with COVID-19 infected patients, contact history with febrile patients or subjects with respiratory tract symptoms from the high epidemic or cluster outbreak area, report of fever or respiratory tract symptoms, or newly emerging ground-glass opacities on a computerized chest tomography (CT) scan Aerosol generating procedures that take place at home are home NIV systems, either CPAP or a BPAP, home oxygen therapy, and sometimes home diagnostics like home sleep apnea testing systems.
    keywords: aerosol; covid-19; home; mask; niv; patients; procedures; sleep
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        item: #7653 of 7819
          id: cord-354337-a70avg2x
      author: Mehraeen, Esmaeil
       title: A systematic review of ECG findings in patients with COVID-19
        date: 2020-11-13
       words: 3151
      flesch: 46
     summary: Drug induced QT prolongation and torsades de pointes In-hospital cardiac arrest outcomes among patients with COVID-19 pneumonia in Wuhan Cardiac Involvement in a Patient with Coronavirus Disease 2019 (COVID-19) ST-Segment Elevation in Patients with Covid-19 -A Case Series. The other four studies administered both monotherapy (chloroquine/hydroxychloroquine) and combination treatmentfor COVID-19 patients and confirmed that combination therapy is associated with a higher risk of QTc interval prolongation compared with monotherapy (18) (19) (20) (21) .
    keywords: cardiac; case; changes; covid-19; ecg; patients; qtc; studies
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        item: #7654 of 7819
          id: cord-354339-tchu91av
      author: Shahzad, Naeem
       title: Rapid assessment of COVID-19 suspected cases: A community based approach for developing countries like Pakistan
        date: 2020-05-06
       words: 2124
      flesch: 44
     summary: key: cord-354339-tchu91av authors: Shahzad, Naeem; Abid, Irfan; Mirza, Wajahat Javed; Iqbal, Muhammad Mazhar title: Rapid assessment of COVID-19 suspected cases: A community based approach for developing countries like Pakistan date: 2020-05-06 journal: Journal of global health DOI: 10.7189/jogh.10.010353 sha: doc_id: 354339 cord_uid: tchu91av nan T he Coronavirus pandemic started in late December 2019, when an unexplained case of mass pneumonia occurred in Wuhan, China raising concern of the responsible health department of the City. This score card has been designed for low income countries with no or limited testing capabilities of COVID-19 tests.
    keywords: countries; covid-19; health; score; testing
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        item: #7655 of 7819
          id: cord-354349-hbk2p6ej
      author: Sardar, Sundus
       title: COVID-19 and Plasmodium vivax malaria co-infection
        date: 2020-06-20
       words: 1727
      flesch: 38
     summary: The need for combination therapy with non-anti-SARS-CoV-2 agents? Roles and challenges of primary care physicians facing a dual outbreak of COVID-19 and dengue in Singapore Malaria and Parasitic Neglected Tropical Diseases: Potential Syndemics with COVID-19? Mass intake of hydroxychloroquine or chloroquine in the present context of the Covid-19 outbreak: Possible consequences in endemic malaria settings Artesunate: could be an alternative drug to chloroquine in COVID-19 treatment The first authors (SS and RS) contributed equally to the writing and preparation of this article. Malaria and COVID-19 coinfection could then lead to excessive pro-inflammatory response leading to severe manifestations and poor prognosis [13] .
    keywords: cov-2; covid-19; infection; malaria; sars
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        item: #7656 of 7819
          id: cord-354353-hyz0gmpz
      author: Farhangrazi, Z. Shadi
       title: Airborne Particulate Matter and SARS-CoV-2 Partnership: Virus Hitchhiking, Stabilization and Immune Cell Targeting — A Hypothesis
        date: 2020-09-24
       words: 2467
      flesch: 29
     summary: For instance, a recent epidemiological study concluded that an increase of 1 µg/m 3 in long-term exposure to fine PM air pollutants (≤2.5 µm, PM 2.5 ) is associated with an 8% increase in COVID-19 mortality rate in the United States (3). While long-term exposure to air pollutants such as PM 2.5 and nitrous dioxide contributes to persistent inflammatory responses and cardiopulmonary diseases (7) , which might increase vulnerability to COVID-19, it is also plausible that depending on the environment SARS-CoV-2 hitchhiking on airborne PM pollutants might be an additional mechanism for spreading the infection.
    keywords: air; covid-19; infection; pollution; sars; virus
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        item: #7657 of 7819
          id: cord-354371-321vd28d
      author: Hinchman, Angelica
       title: Global Health Is Local Health: A Multidisciplinary Perspective of COVID-19
        date: 2020
       words: 6595
      flesch: 41
     summary: Among 13,909 cases, confirmed COVID-19 positive patients ࣙ60 years of age had a 4.06% mortality rate. [8] [9] [10] The government's facilitation of communication between healthcare experts and the public during an emerging pandemic amplified an existing challenge in public health: finding a balance between informing the public of imminent health threats while preventing increased anxiety and panic in response to elevated risk perceptions.
    keywords: access; americans; care; coronavirus; covid-19; data; disease; health; healthcare; louisiana; new; orleans; pandemic; patients; public; response; states
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        item: #7658 of 7819
          id: cord-354373-lldfoptb
      author: Chi, Jeffrey
       title: COVID-19 Clinical Research
        date: 2020-05-05
       words: 2495
      flesch: 45
     summary: At the present time, cancer patients are eligible for the vast majority of COVID-19 clinical trials regardless of cancer directed treatment status. In a recent open-label, non-randomized trial, Gautret et al. showed significant reduction in viral load in COVID-19 patients treated with hydroxychloroquine [8] .
    keywords: coronavirus; cov-2; covid-19; patients; phase; sars; treatment; trials
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        item: #7659 of 7819
          id: cord-354376-ghxy727r
      author: Duggan, Nicole M.
       title: Best practice recommendations for point-of-care lung ultrasound in patients with suspected COVID-19
        date: 2020-06-12
       words: 1213
      flesch: 35
     summary: Website: 179 Complete GUIDE to LUNG ultrasound in COVID-19 (Coronavirus) Patients. Intensiv Care Med Available at Correlation of Chest CT and RT-PCR Testing in Coronavirus 219 Disease 2019 (COVID-19) in China: A Report of 1014 Cases Radiological findings from 81 patients with COVID-19 222 pneumonia in Wuhan, China: a descriptive study Proposal for international standardization of 225 the use of lung ultrasound for COVID-19 patients; a simple, quantitative, reproducible 226 method Prone positioning in severe acute respiratory 228 distress syndrome Lower mortality of COVID-19 by early recognition 231 and intervention: experience from Jiangsu Province.
    keywords: covid-19; lung; patients; ultrasound
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        item: #7660 of 7819
          id: cord-354389-l2erwez8
      author: Street, Maria Elisabeth
       title: HMGB1: A Possible Crucial Therapeutic Target for COVID-19?
        date: 2020-05-06
       words: 1431
      flesch: 38
     summary: Thus, pharmacological inhibition of JAK/STAT1 could be an approach for reducing circulating HMGB1 [20] . The inflammasome mediates HMGB1 translocation from the nucleus to the cytoplasm, with subsequent release from the cell via type 1 interferon JAK/STAT1 activation.
    keywords: covid-19; diabetes; hmgb1; patients; sars
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        item: #7661 of 7819
          id: cord-354395-5ss8vni5
      author: Huang, G.
       title: Staging and typing of chest CT images: A quantitative analysis based on an ambispective observational cohort study of 125 patients with COVID-19 in Xiangyang, China
        date: 2020-10-27
       words: 3801
      flesch: 50
     summary: The relevant guidelines have put forward the durations of CT stages The categorical regression analysis based on optimal scale (CATREG) was performed to evaluate the association of CT score, age, and gender with the clinical type.
    keywords: medrxiv; patients; preprint; stage; type
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        item: #7662 of 7819
          id: cord-354411-4emzxu09
      author: Nouvenne, Antonio
       title: Lung Ultrasound in COVID-19 Pneumonia: Correlations with Chest CT on Hospital admission
        date: 2020-06-22
       words: 3970
      flesch: 37
     summary: METHODS: Twenty-six patients (14 males, age 64 ± 16 years) urgently hospitalized for COVID-19 pneumonia, who underwent chest CT and bedside LUS on the day of admission, were enrolled in this observational study. The sensitivity of CT for diagnosing COVID-19 pneumonia is 97% considering the results of reverse-transcription polymerase-chain reaction (RT-PCR) tests as gold standard [2] .
    keywords: chest; covid-19; findings; lung; lus; patients; pneumonia; score; ultrasound
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        item: #7663 of 7819
          id: cord-354421-tqv2y7ey
      author: Wetzler, H. P.
       title: New Insights on Excess Deaths and COVID-19
        date: 2020-07-27
       words: 1036
      flesch: 57
     summary: Conclusion: Combining the 95,235 reported COVID-19 deaths with the 18,489 from the 13 most frequent comorbid conditions reported on death certificates where COVID-19 was a cause suggests that as many as 93% of the excess deaths were due to COVID-19 and implies that COVID-19 deaths were undercounted. Combining the 95,235 reported COVID-19 deaths with the 18,489 from the 13 most frequent comorbid conditions reported on death certificates where COVID-19 was a cause suggests that as many as 93% of the excess deaths between March 1 and May 30, 2020 were due to COVID-19 and implies that COVID-19 deaths were undercounted.
    keywords: covid-19; deaths
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        item: #7664 of 7819
          id: cord-354426-cp6tomfw
      author: Her, Minyoung
       title: How Is COVID-19 Affecting South Korea? What Is Our Current Strategy?
        date: 2020-04-03
       words: 1859
      flesch: 53
     summary: Thus, early COVID-19 screening is the key to curbing transmission. COVID-19 screening was performed for patients who were strongly suspected of having COVID-19, as well as many asymptomatic groups with epidemiological evidence suggesting the possibility of infection.
    keywords: covid-19; korea; patients; south
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        item: #7665 of 7819
          id: cord-354434-bi409a6o
      author: Benjamin, Georges C.
       title: Ensuring health equity during the COVID-19 pandemic: the role of public health infrastructure
        date: 2020-05-29
       words: 2388
      flesch: 41
     summary: The COVID-19 pandemic has significantly stressed public health systems around the world and exposed the gaps in health care for underserved and vulnerable populations. Given that about 80% of what makes one healthy occurs outside of the clinical setting, public health systems are working diligently to address the social determinants of health.
    keywords: covid-19; health; los; pandemic; public; salud; saúde; systems; world
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        item: #7666 of 7819
          id: cord-354468-bew35s8q
      author: Margus, Colton
       title: Discharge in pandemic: Suspected Covid-19 patients returning to the Emergency Department within 72 hours for admission
        date: 2020-08-18
       words: 4025
      flesch: 40
     summary: While not considered a favorable outcome, ED return admission does not necessarily indicate an error in disposition decision. Additionally, timeframes longer than 72 hours may also serve as appropriate cutoffs for reviewing ED return admissions.
    keywords: admission; covid-19; discharge; disease; emergency; hours; patients; return; study
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        item: #7667 of 7819
          id: cord-354472-zixnvehs
      author: Esposito, A.
       title: Why is chest CT important for early diagnosis of COVID-19? Prevalence matters
        date: 2020-04-01
       words: 2585
      flesch: 37
     summary: Computed Tomography (CT) scan represents the gold standard in the diagnosis and characterization of interstitial lung diseases, including viral pneumonia 5 . Mostly reported COVID-19 CT findings include multifocal ground-glass opacities, affecting both lungs, with peripheral distribution, more frequently involving posterior segments ( Figure 1 ). Moreover, the recent introduction of artificial intelligence (AI) approaches as diagnostic tools for semi-automated COVID-19 CT scan reporting may even shorten this time and improve performances 41 .
    keywords: covid-19; disease; patients; pcr
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        item: #7668 of 7819
          id: cord-354474-hbl2ywix
      author: Temsah, M. H.
       title: Knowledge, attitudes and practices of healthcare workers during the early COVID-19 pandemic in a main, academic tertiary care centre in Saudi Arabia
        date: 2020-08-28
       words: 4150
      flesch: 43
     summary: In addition, we assessed [19] the perceived adequacy of COVID-19 information and [15] perceived high fear/stress from the COVID-19 pandemic as compared to the previous MERS-CoV outbreak. A higher perceived adequacy of COVID-19 information (mean: 3.97 ± 1.00 vs. 3.7 ± 0.92, P = 0.001) and better hygienic practices (3.10 ± 0.84 vs. 2.65 ± 0.87, P < 0.001) were observed among HCWs who attended the Educational Day conference (Fig. 2) .
    keywords: covid-19; hcws; knowledge; mers; pandemic; study
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        item: #7669 of 7819
          id: cord-354491-23cjm86c
      author: Muller, A. E.
       title: The mental health impact of the covid-19 pandemic onhealthcare workers, and interventions to help them: a rapid systematic review
        date: 2020-07-04
       words: 7865
      flesch: 41
     summary: The studies reported on healthcare workers working in different settings: 43 studies reported on health care workers in hospitals, two studies were conducted in specialist health services outside hospitals, and three studies in other settings, while 21 studies did not specify the healthcare setting or only partially described multiple settings. The copyright holder for this preprint (which this version posted The impact of the covid-19 pandemic on mental health of health care workers: protocol for a rapid systematic review A systematic and living evidence map on COVID-19 AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both CASP checklist for qualitative research GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables Addressing Faculty Emotional Responses During the COVID19 Pandemic Anxiety and Depression Survey of Chinese Medical Staff Before and During COVID-19 Defense Assessment of Iranian nurses′ knowledge and anxiety toward COVID-19 during the current outbreak in Iran Assessment of the Mental Health of Front Line Healthcare Workers in a COVID-19 Epidemic Epicenter of China At the height of the storm: Healthcare staff's health conditions and job satisfaction and their associated predictors during the epidemic peak of COVID-19 Brief Psychotic Disorder Triggered by Fear of Coronavirus? Comparison of the Indicators of Psychological Stress in the Population of Hubei Province and Non-Endemic Provinces in China During Two Weeks During the Coronavirus Disease 2019 (COVID-19) Outbreak in February 2020 COVID19 pandemic impacts on anxiety of French urologist in training: Outcomes from a national survey COVID-19 and mental health: A review of the existing literature COVID-19 and paediatric health services: A survey of paediatric physicians in Australia and New Zealand COVID-19 associated psychiatric symptoms in healthcare workers: viewpoint from internal medicine and psychiatry residents COVID-19 outbreak situation and its psychological impact among surgeon in training in France COVID-19-Related Information Sources and Psychological Well-being: An Online Survey Study in Taiwan A cross-sectional study on mental health among health care workers during the outbreak of Corona Virus Disease The Effects of Social Support on Sleep Quality of Medical Staff Treating Patients with Coronavirus Disease 2019 (COVID-19) in January and February 2020 in China Emergency Responses to COVID-19 Outbreak: Experiences and Lessons from a General Hospital in Nanjing Evaluation of the Level of Anxiety among Iranian Multiple Sclerosis Fellowships During the Outbreak of COVID-19 Factors Associated With Mental Health Outcomes Among Health Care Workers Exposed to Coronavirus Disease Fear and Practice Modifications among Dentists to Combat Novel Coronavirus Disease (COVID-19) Outbreak The immediate mental health impacts of the COVID-19 pandemic among people with or without quarantine managements The Impact of COVID-19 Pandemic on Spine Surgeons Worldwide Impact on mental health and perceptions of psychological care among medical and nursing staff in Wuhan during the 2019 novel coronavirus disease outbreak: A cross-sectional study Investigation and analysis of the psychological status of the clinical nurses in a class A hospital facing the novel coronavirus pneumonia Issues relevant to mental health promotion in frontline health care providers managing quarantined/isolated COVID19 patients Mental Health and Psychosocial Problems of Medical Health Workers during the COVID-19 Epidemic in China Mental health care for medical staff in China during the COVID-19 outbreak.
    keywords: author; covid-19; healthcare; license; medrxiv; mental; pandemic; preprint; psychological; review; studies; study; workers
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        item: #7670 of 7819
          id: cord-354492-6r6qs4pp
      author: Messina, Giovanni
       title: Functional Role of Dietary Intervention to Improve the Outcome of COVID-19: A Hypothesis of Work
        date: 2020-04-28
       words: 6885
      flesch: 32
     summary: An interesting study reported that systemic adiponectin concentrations in humans fall during the acute phase of lung infection: particularly, during the early phase, the pro-inflammatory state is generated by the high systemic TNF-α and IL-6 concentrations, with the subsequent inhibition of adiponectin production. As previously described, other dietary constituents can be used to improve the patients' outcomes during lung infection, regulating the inflammatory response.
    keywords: acute; adiponectin; covid-19; il-6; infection; inflammation; levels; lung; patients; response; role; tnf; ω-3
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        item: #7671 of 7819
          id: cord-354498-ddzeznxn
      author: Haddadi, Sara
       title: COVID-19: Risk of Alcohol abuse and Psychiatric disorders
        date: 2020-09-14
       words: 1463
      flesch: 50
     summary: This high-risk group of COVID-19 patients may not only suffer from the effects of J o u r n a l P r e -p r o o f alcohol misuse but also it is likely that they be incompliant to the self-quarantine instructions when they are suspicious for COVID-19. A higher rate of alcohol abuse in psychiatric patients and their lower compliance to self-quarantine calls for a different approach when they come to the ED with COVID-19 presentations.
    keywords: abuse; alcohol; covid-19; patients
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        item: #7672 of 7819
          id: cord-354534-0b7zwzjv
      author: Fuccillo, E
       title: Olfactory disorders in coronavirus disease 2019 patients: a systematic literature review
        date: 2020-09-15
       words: 2847
      flesch: 30
     summary: London: ENT UK Association of chemosensory dysfunction and Covid-19 in patients presenting with influenza-like symptoms Postviral olfactory loss SARS-CoV-2: olfaction, brain infection, and the urgent need for clinical samples allowing earlier virus detection First ultrastructural autoptic findings of SARS-Cov-2 in olfactory pathways and brainstem The prevalence of olfactory and gustatory dysfunction in COVID-19 patients: a systematic review and meta-analysis COVID-19 in otolaryngologist practice: a review of current knowledge Clinical presentation of COVID-19: a systematic review focusing on upper airway symptoms Corona viruses and the chemical senses: past, present, and future [2] (COVID-19) Olfactory and gustatory function impairment in COVID-19 patients: Italian objective multicenter-study Objective evaluation of anosmia and ageusia in COVID-19 patients: singlecenter experience on 72 cases Validation of a self-administered olfactory and gustatory test for the remotely evaluation of COVID-19 patients in home quarantine The role of self-reported olfactory and gustatory dysfunction as a screening criterion for suspected COVID-19 Self-reported olfactory loss associates with outpatient clinical course in Covid-19 Contribution of anosmia and dysgeusia for diagnostic of COVID-19 in outpatients Self-reported Mini Olfactory Questionnaire (Self-MOQ): a simple and useful measurement for the screening of olfactory dysfunction Screening of olfactory function with a four-minute odor identification test: reliability, normative data, and investigations in patients with olfactory loss Olfactory dysfunction: properties of the Sniffin' Sticks Screening 12 test and associations with quality of life A brief version of the questionnaire of olfactory disorders in patients with chronic rhinosinusitis Prevalence and risk factors of self-reported smell and taste alterations: results from the 2011-2012 US National Health and Nutrition Examination Survey (NHANES) Evaluation of Open Essence odor-identification test card by application to healthy volunteers The shelf life of the University of Pennsylvania Smell Identification Test (UPSIT)
    keywords: covid-19; disorders; dysfunction; olfactory; patients; smell
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        item: #7673 of 7819
          id: cord-354575-f5fq75up
      author: Gupta, Latika
       title: Scholarly publishing and journal targeting in the time of the Coronavirus Disease 2019 (COVID-19) pandemic: a cross-sectional survey of rheumatologists and other specialists
        date: 2020-10-13
       words: 3585
      flesch: 39
     summary: High-quality peer review (56%), full and immediate open access (46%) and post-publication social media promotion (32%) were identified as key anticipated features of scholarly publishing in the foreseeable future. The rise in social media use during this pandemic may result in timely identification and promotion of publications vis-a-vis conventional metrics that may delay impact on education, research, and practice
    keywords: covid-19; journals; media; pandemic; publication; publishing; respondents; survey
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        item: #7674 of 7819
          id: cord-354588-jxzdrxqx
      author: Campos, I. S.
       title: A vulnerability analysis for the management of and response to the COVID-19 epidemic in the second most populous state in Brazil
        date: 2020-07-25
       words: 5552
      flesch: 39
     summary: Personal protective equipment during the coronavirus disease (COVID) 2019 pandemic -a narrative review Effects of nonpharmaceutical interventions on COVID-19 cases, deaths, and demand for hospital services in the UK: a modelling study Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe COVID-19 attack rate increases with city size. https://doi.org/10.1101/2020.07.20.20158345 doi: medRxiv preprint municipalities of Teófilo Otoni and Governador Valadares, not reaching all the surrounding municipalities (62) .
    keywords: author; covid-19; health; indicators; license; medrxiv; medrxiv preprint; municipalities; perpetuity; preprint; state
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        item: #7675 of 7819
          id: cord-354608-1me3nopu
      author: Rabinowicz, Shira
       title: COVID-19 in the Pediatric Population—Review and Current Evidence
        date: 2020-09-19
       words: 5429
      flesch: 38
     summary: Epidemiology of COVID-19 among children in China Coronavirus disease 2019 in children -United States Department of Health and Human Services SARS-COV-2 infection in children and newborns : a systematic review Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor SARS-CoV-2 detection, viral load and infectivity over the course of an infection Age-related differences in nasopharyngeal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) levels in patients with mild to moderate coronavirus disease American Medical Association The immune system of children: the key to understanding SARS-CoV-2 susceptibility? COVID-19 pathophysiology: a review Pathophysiology of COVID-19: Why children fare better than adults? Daycare attendance and respiratory tract infections: a prospective birth cohort study The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases ( COVID-19 ) -China Coronavirus disease 2019 (COVID-19) in Italy Children with COVID-19 in Pediatric Emergency Departments in Italy SARS-CoV-2 Infection in children Articles COVID-19 in children and adolescents in Europe : a multinational , multicentre cohort study COVID-19 in children and the dynamics of infection in families Coinfection and other clinical characteristics of COVID-19 in children SARS-CoV-2 transmission and infection among attendees of an overnight camp -Georgia A large COVID-19 outbreak in a high school 10 days after schools' reopening, Israel Plan for school reopening | IIEP-UNESCO Asymptomatic transmission and the infection fatality risk for COVID-19: implications for school reopening Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China COVID-19: consider cytokine storm syndromes and immunosuppression Anosmia and ageusia: common findings in COVID-19 patients Anosmia and ageusia: not an uncommon presentation of COVID-19 infection in children and adolescents Hospitalization rates and characteristics of children aged <18 years hospitalized with laboratory-confirmed COVID-19 -COVID-NET, 14 States Characteristics and outcomes of children with coronavirus disease 2019 (COVID-19) infection admitted to US and Canadian Pediatric Intensive Care Units Clinical characteristics and outcomes of hospitalized and critically ill children and adolescents with coronavirus disease 2019 at a tertiary care medical center Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Care of newborns born to mothers with COVID-19 infection; a review of existing evidence Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan Maternal and perinatal outcomes with COVID-19: a systematic review of 108 pregnancies Neonatal resuscitation and postresuscitation care of infants born to mothers with suspected or confirmed SARS-CoV-2 infection Transplacental transmission of SARS-CoV-2 infection Neonatal early-onset infection with SARS-CoV-2 in 33 neonates born to mothers with COVID-19 in Wuhan An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 Multisystem inflammatory syndrome with features of atypical Kawasaki disease during COVID-19 pandemic Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic Hyperinflammatory shock in children during COVID-19 pandemic COVID-19-associated multisystem inflammatory syndrome in children -United States Multisystem inflammatory syndrome in U.S. children and adolescents Multi-system inflammatory syndrome in children (MIS-C) following SARS-CoV-2 infection: review of clinical presentation, hypothetical pathogenesis, and proposed management COVID-19 and multisystem inflammatory syndrome in children and adolescents Acute heart failure in multisystem inflammatory syndrome in children (MIS-C) in the context of global SARS-CoV-2 pandemic American College of Rheumatology Clinical Guidance for Pediatric Patients with Multisystem Inflammatory Syndrome in Children (MIS-C) associated with SARS-CoV-2 and hyperinflammation in COVID-19. Microorganisms Supportive treatment with tocilizumab for COVID-19: a systematic review Managing childhood allergies and immunodeficiencies during respiratory virus epidemics -The 2020 COVID-19 pandemic : a statement from the EAACI-section on pediatrics Considerations on biologicals for patients with allergic disease in times of the COVID-19 pandemic: an EAACI Statement Characteristics and outcomes of Coronavirus Infection in Children: The role of viral factors and an immunocompromised state Coronaviruses and immunosuppressed patients: the facts during the third epidemic COVID-19 in immunocompromised hosts: what we know so far Reluctance to seek pediatric care during the COVID-19 pandemic and the risks of delayed diagnosis Delayed emergency surgical presentation: impact of corona virus disease (COVID-19) on non-COVID patients Gathering evidence on the decreased emergency room visits during the coronavirus disease 19 pandemic Routine vaccination during covid-19 pandemic response Masked paediatricians during the COVID -19 pandemic and communication with children Pandemic school closures: risks and opportunities ADHD management during the COVID-19 pandemic: guidance from the European ADHD Guidelines Group Acute stress, behavioural symptoms and mood states among school-age children with attention-deficit/hyperactive disorder during the COVID-19 outbreak Starting ADHD medications during the COVID-19 pandemic: recommendations from the European ADHD Guidelines Group Challenges and burden of the Coronavirus 2019 (COVID-19) pandemic for child and adolescent mental health: a narrative review to highlight clinical and research needs in the acute phase and the long return to normality Impact of COVID-19 and lockdown on mental health of children and adolescents: a narrative review with recommendations An investigation of mental health status of children and adolescents in china during the outbreak of COVID-19 Mental health status among children in home confinement during the coronavirus disease Child protection in the time of <scp>COVID</ scp> -19.
    keywords: adults; children; coronavirus; cov-2; covid-19; disease; health; infection; pandemic; patients; sars; syndrome; treatment
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        item: #7676 of 7819
          id: cord-354619-pftjhtpo
      author: Farronato, Marco
       title: A Call for Action to Safely Deliver Oral Health Care during and Post COVID-19 Pandemic
        date: 2020-09-15
       words: 5048
      flesch: 42
     summary: A first step in understanding SARS pathogenesis Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme Virion-Associated Cholesterol Regulates the Infection of Human Parainfluenza Virus Type 3 Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2 Multifaceted roles for lipids in viral infection Regulation of raft-dependent endocytosis PEDV enters cells through clathrin-, caveolae-, and lipid raftmediated endocytosis and traffics via the endo-/lysosome pathway Cholesterol Enhances Mouse Hepatitis Virus-Mediated Cell Fusion Natural small molecules as inhibitors of coronavirus lipid-dependent attachment to host cells: A possible strategy for reducing SARS-COV-2 infectivity? Chloroquine is a potent inhibitor of SARS coronavirus infection and spread Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 Clinical characteristics of coronavirus disease 2019 in China Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents Characterization of Pathogenic Bacteria Isolated from Sudanese Banknotes and Determination of Their Resistance Profile Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient Clinical characteristics of coronavirus disease 2019 (COVID-19) in China: A systematic review and meta-analysis Clinical and demographic characteristics of patients dying from COVID-19 in Italy versus China COVID-19 Lombardy ICU Network. The main limitation of these recommendations is represented from COVID-19 asymptomatic patients (negative to triage) that are not at the moment correctly identified.
    keywords: ace2; consultations; cov-2; covid-19; dental; dhcw; evidence; health; infection; patients; sars; transmission
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        item: #7677 of 7819
          id: cord-354627-y07w2f43
      author: pinter, g.
       title: COVID-19 Pandemic Prediction for Hungary; a Hybrid Machine Learning Approach
        date: 2020-05-06
       words: 5485
      flesch: 45
     summary: As an alternative to the SIR-based models, this study proposed machine learning as a new trend in advancing outbreak models. Outbreak prediction models have shown to be essential to communicate insights into the likely spread and consequences of COVID-19.
    keywords: algorithm; covid-19; data; learning; license; machine; models; outbreak; prediction; preprint; sir; time
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        item: #7678 of 7819
          id: cord-354658-v451z3jq
      author: Rajagopal, Keshava
       title: Advanced Pulmonary and Cardiac Support of COVID-19 Patients: Emerging Recommendations From ASAIO—A “Living Working Document”
        date: 2020-05-11
       words: 8894
      flesch: 36
     summary: The ELSO Guidance Document: ECMO for COVID-19 Patients with Severe Cardiopulmonary Failure describes usage of ECMO in COVID-19 patients intended for experienced ECMO centers. key: cord-354658-v451z3jq authors: Rajagopal, Keshava; Keller, Steven P.; Akkanti, Bindu; Bime, Christian; Loyalka, Pranav; Cheema, Faisal H.; Zwischenberger, Joseph B.; El Banayosy, Aly; Pappalardo, Federico; Slaughter, Mark S.; Slepian, Marvin J. title: Advanced Pulmonary and Cardiac Support of COVID-19 Patients: Emerging Recommendations From ASAIO—A “Living Working Document” date: 2020-05-11 journal: ASAIO J DOI: 10.1097/mat.0000000000001180 sha: doc_id: 354658 cord_uid: v451z3jq The severe acute respiratory syndrome (SARS)-CoV-2 is an emerging viral pathogen responsible for the global coronavirus disease 2019 (COVID)-19 pandemic resulting in significant human morbidity and mortality.
    keywords: acute; arterial; cannulation; coronavirus; covid-19; disease; ecmo; failure; flow; infection; lung; patients; pressure; sars; setting; shock; support
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        item: #7679 of 7819
          id: cord-354661-wls1rd7d
      author: Suen, Yiu-tung
       title: Effects of general and sexual minority-specific COVID-19-related stressors on the mental health of lesbian, gay and bisexual people in Hong Kong
        date: 2020-08-03
       words: 5047
      flesch: 43
     summary: Minority stress theory proposes that sexual minority health disparities can be explained in large part by stressors induced by a hostile, homophobic social environment, in which LGB people have to live with harassment, maltreatment, discrimination and victimization (Frost et al., 2015; Meyer, 2013) . Nevertheless, due to the implementation of social distancing restrictions, sexual minority people may have fewer access to LGBT+ community during the COVID-19 pandemic.
    keywords: covid-19; health; lgb; pandemic; people; stressors; symptoms
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        item: #7680 of 7819
          id: cord-354689-dsv63it1
      author: Chen, Qian
       title: Precautionary Measures: Performing ERCP on a Patient With Juxtapapillary Duodenal Diverticula (JPDD)-Related Biliary Stone After COVID-19 Lockdown Restriction Lifted in Wuhan, China
        date: 2020-09-04
       words: 3543
      flesch: 34
     summary: Based on our experiences, the objective is to provide practical suggestions for the safe resumption of ERCP procedures in the setting of the COVID-19 pandemic with specific focus on patient risk assessment, personal protection equipment (PPE), and dress code modalities, all of which have been implemented in our hospital to reduce the risk of viral transmission. The vital parameters [heart rate (HR), blood pressure (BP), FIGURE 1 | Patient management and risk assessment and detailed workflow during ERCP procedure.
    keywords: acute; covid-19; endoscopy; ercp; pancreatitis; patient; procedure; risk
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        item: #7681 of 7819
          id: cord-354699-u4s2r8gy
      author: de Souza, Carlos Dornels Freire
       title: Human development, social vulnerability and COVID-19 in Brazil: a study of the social determinants of health
        date: 2020-08-31
       words: 3924
      flesch: 44
     summary: We observed that 56.2% of municipalities with confirmed cases had very low human development (COVID-19 incidence rate: 59.00/100 000; mortality rate: 36.75/1 000 000), and 52.8% had very high vulnerability (COVID-19 incidence rate: 41.68/100 000; mortality rate: 27.46/1 000 000). Regarding incidence and COVID-19 mortality rate, the group with very low MHDI held third place (COVID-19 incidence rate: 59.00/100000 and COVID-19 mortality rate: 36.75/1 million) (Tables 1 and 2) .
    keywords: brazil; covid-19; incidence; municipalities; percentage; rate; social; vulnerability; years
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        item: #7682 of 7819
          id: cord-354702-hi4nxf67
      author: Laszkowska, Monika
       title: Disease Course and Outcomes of COVID-19 Among Hospitalized Patients with Gastrointestinal Manifestations
        date: 2020-09-30
       words: 3388
      flesch: 38
     summary: In this study, we found that hospitalized individuals with COVID-19 who presented with gastrointestinal symptoms of diarrhea, nausea, vomiting, or abdominal pain were younger but had more co-morbidities than those presenting without GI symptoms. In conclusion, our study demonstrates that individuals with gastrointestinal symptoms including diarrhea, nausea, vomiting, and abdominal pain have lower rates of intubation and death than those without GI symptoms.
    keywords: covid-19; disease; gastrointestinal; patients; symptoms
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        item: #7683 of 7819
          id: cord-354715-zofba2b4
      author: Ransing, Ramdas
       title: Can COVID-19 related mental health issues be measured?: Assessment options for mental health professionals
        date: 2020-05-26
       words: 1127
      flesch: 39
     summary: There are new scales tailored to identify COVID-19 related mental health issues (Lee, 2020a; Taylor et al., 2020) , however, their clinical utility with methodological strengths and limitations have not yet been discussed in the literature. A lack of specific robust screening tools or diagnostic instruments to identify relevant symptoms and attempts to study the epidemiology of COVID-19 related mental health issues using traditional assessment tools (e.g. PHQ-9, GAD-7) may lead to under-diagnosis or over-diagnosis due to their poor psychometric properties (e.g. face validity).
    keywords: anxiety; covid-19; scales
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        item: #7684 of 7819
          id: cord-354720-fu19u2b0
      author: White-Dzuro, Gabrielle
       title: Multisystem effects of COVID-19: a concise review for practitioners
        date: 2020-11-04
       words: 5093
      flesch: 29
     summary: Is the prone position helpful during spontaneous breathing in patients with COVID-19? In-hospital airway management of COVID-19 patients Lymphopenia predicts disease severity of COVID-19: a descriptive and predictive study High-volume hemofiltration for septic acute kidney injury: a systematic review and meta-analysis Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Comparison of published guidelines for management of coagulopathy and thrombosis in critically ill patients with COVID 19: implications for clinical practice and future investigations Neurologic manifestations of hospitalized patients with Coronavirus Disease Guillain-Barré Syndrome Associated with SARS-CoV-2 Central nervous system manifestations of COVID-19: a systematic review Organ distribution of severe acute respiratory syndrome (SARS) associated coronavirus (SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways Central nervous system involvement by severe acute respiratory syndrome Coronavirus −2 (SARS-CoV-2) Post mortem findings in COVID-19 patients show viral elements within endothelial cells, an accumulation of inflammatory cells, and cellular apoptosis in multiple organs [6] .
    keywords: acute; coronavirus; cov-2; covid-19; disease; effects; infection; injury; patients; risk; sars
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        item: #7685 of 7819
          id: cord-354774-uoewzkjt
      author: Setzen, Michael
       title: The novel corona virus and rhinology: Impact on practice patterns and future directions
        date: 2020-06-01
       words: 2671
      flesch: 44
     summary: In addition to severely impacting practice volume and the perception of future decreases in patients and revenue, the COVID-19 pandemic has had a physical impact and significant emotional impact on rhinologists in ways that need to be further studied. key: cord-354774-uoewzkjt authors: Setzen, Michael; Svider, Peter; Setzen, Sean; Setzen, Gavin; Eloy, Jean Anderson; Johnson, Andrew P. title: The novel corona virus and rhinology: Impact on practice patterns and future directions date: 2020-06-01 journal: Am J Otolaryngol DOI: 10.1016/j.amjoto.2020.102569 sha: doc_id: 354774 cord_uid: uoewzkjt OBJECTIVES: To evaluate the impact of the novel coronavirus pandemic on practice patterns, clinical behavior, personal health, and emotional/psychological concerns of rhinologists.
    keywords: covid-19; endoscopy; pandemic; practice; rhinologists
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        item: #7686 of 7819
          id: cord-354778-fqfzznns
      author: Zhang, Jian
       title: The associated factors of cesarean section during COVID-19 pandemic: a cross-sectional study in nine cities of China
        date: 2020-10-10
       words: 3495
      flesch: 46
     summary: Gestational weight gain among American Samoan women and its impact on delivery and infant outcomes A population-based study on gestational weight gain according to body mass index in the Southeast of Brazil Association of prepregnancy body mass index, gestational weight gain with cesarean section in term deliveries of China Selfquarantine and weight gain related risk factors during the COVID-19 pandemic How to curb emotional eating during the COVID-19 pandemic Emotional eating in pregnant women during the COVID-19 pandemic and its association with dietary intake and gestational weight gain Exercise in pregnancy: a clinical review Gestational weight gain, macrosomia, and risk of cesarean birth in nondiabetic nulliparas The scope and impact of mobile health clinics in the United States: a literature review Rapid deployment of a drive-through prenatal care model in response to the coronavirus disease 2019 (COVID-19) pandemic Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations A dearth of studies on pregnancy health during the COVID-19 pandemic advocates further studies to confirm health threat on women and neonatal and to provide a more targeted support.
    keywords: covid-19; health; pregnancy; study; weight; women
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        item: #7687 of 7819
          id: cord-354792-6ckgxn9l
      author: Ghosh, Mousam
       title: Dynamic Model of Infected Population Due to Spreading of Pandemic COVID-19 Considering Both Intra and Inter Zone Mobilization Factors with Rate of Detection
        date: 2020-10-19
       words: 3417
      flesch: 42
     summary: Further, factor ( ) to find the cured/recovered population from detected infected population has been determined taking = 5 with moving average basis (Fig. A1(b) ). Further how such infected population in each zone changes due the crucial realistic cause of spreading such as intra and inter zone mobilization factors with rate of detection has been estimated.
    keywords: covid-19; model; population; time; zone
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        item: #7688 of 7819
          id: cord-354819-gkbfbh00
      author: Islam, Md. Zabirul
       title: A Combined Deep CNN-LSTM Network for the Detection of Novel Coronavirus (COVID-19) Using X-ray Images
        date: 2020-08-15
       words: 3681
      flesch: 49
     summary: In this study, a combined method was developed to automatically detect COVID-19 cases using three types of X-ray images. Clinical features of patients infected with 2019 novel coronavirus in Coronavirus Disease Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application Predictive Data Mining Models for Novel Coronavirus (COVID-19) Infected Patients Recovery COVID-19): Role of Chest CT in Diagnosis and Management Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR A Survey on Computer Vision for Assistive Medical Diagnosis from Faces Prediction of breast cancer using support vector machine and K-Nearest neighbors Performance Evaluation of Random Forests and Artificial Neural Networks for the Classification of Liver Disorder Mathematical model development to detect breast cancer using multigene genetic programming Diabetes Prediction: A Deep Learning Approach Coronary Artery Heart Disease Prediction: A Comparative Study of Computational Intelligence Techniques Developing IoT Based Smart Health Monitoring Systems: A Review, Rev. d'Intelligence Artif Development of Smart Healthcare Monitoring System in IoT Environment Feature extraction for image recognition and computer vision Optimal deep learning model for classification of lung cancer on CT images Bone suppression of chest radiographs with cascaded convolutional networks in wavelet domain Deep back propagation-long shortterm memory network based upper-limb sEMG signal classification for automated rehabilitation A New Modified Deep Convolutional Neural Network for Detecting COVID-19 from X-ray Images Covid-2019 Detection Using X-Ray Images And Artificial Intelligence Hybrid Systems Within the Lack of Chest COVID-19 Xray Dataset: A Novel Detection Model Based on GAN and Deep Transfer Learning COVIDiagnosis-Net: Deep Bayes-SqueezeNet based diagnosis of the coronavirus disease 2019 (COVID-19) from X-ray images Covid-19: automatic detection from X-ray images utilizing transfer learning with convolutional neural networks Machine Learning Approach for Confirmation of COVID-19 Cases:
    keywords: cnn; covid-19; deep; detection; images; lstm; ray; system
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        item: #7689 of 7819
          id: cord-354824-7fdcu2f0
      author: Wu, Renyi
       title: An Update on Current Therapeutic Drugs Treating COVID-19
        date: 2020-05-11
       words: 9676
      flesch: 38
     summary: Chinese Clinical Trial Registry Why tocilizumab could be an effective treatment for severe COVID-19? Evaluation of the efficacy and safety of sarilumab in hospitalized patients with COVID-19 Overview of the IL-1 family in innate inflammation and acquired immunity Personalised immunotherapy for SARS-CoV-2 (COVID-19) associated with organ dysfunction Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Clinical characteristics of coronavirus disease 2019 in China Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus Genetic associations between genes in the renin-angiotensinaldosterone system and renal disease: a systematic review and meta-analysis Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensinconverting enzyme 2 A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury FDA advises patients on use of non-steroidal anti-inflammatory drugs (NSAIDs) for COVID-19 Peroxisome proliferatoractivated receptor-gamma agonists inhibit respiratory syncytial virus-induced expression of intercellular adhesion molecule-1 in human lung epithelial cells Treating viral exacerbations of chronic obstructive pulmonary disease: insights from a mouse model of cigarette smoke and H1N1 influenza infection Indomethacin has a potent antiviral activity against SARS coronavirus Colchicine-update on mechanisms of action and therapeutic uses Colchicine and the heart: pushing the envelope Inhibition of severe acute respiratory syndrome coronavirus replication by niclosamide SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-coronavirus infection An AlphaScreen®-based assay for high-throughput screening for specific inhibitors of nuclear import Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug The broad spectrum antiviral ivermectin targets the host nuclear transport importin alpha/beta1 heterodimer The FDAapproved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro A screen of the NIH clinical collection small molecule library identifies potential anti-coronavirus drugs Nitazoxanide, a new drug candidate for the treatment of Middle East respiratory syndrome coronavirus Meta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment? Antibody-mediated regulation of cellular immunity and the inflammatory response Serum therapy revisited: animal models of infection and development of passive antibody therapy Fcmediated antibody effector functions during respiratory syncytial virus infection and disease A role for Fc function in therapeutic monoclonal antibody-mediated protection against Ebola virus A serological survey on neutralizing antibody titer of SARS convalescent sera Use of convalescent plasma therapy in SARS patients in Hong Kong Experience of using convalescent plasma for severe acute respiratory syndrome among healthcare workers in a Taiwan hospital Challenges of convalescent plasma infusion therapy in Middle East respiratory coronavirus infection: a single centre experience Deployment of convalescent plasma for the prevention and treatment of COVID-19 Treatment of 5 critically ill patients with COVID-19 with convalescent plasma Effectiveness of convalescent plasma therapy in severe COVID-19 patients Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy The 2019 coronavirus (SARS-CoV-2) surface protein (Spike) S1 receptor binding domain The potential of low molecular weight heparin to mitigate cytokine storm in severe COVID-19 patients: a retrospective clinical study Redeploying plant defences Chinese herbal medicines for the treatment of type a H1N1 influenza: a systematic review of randomized controlled trials Clinical outcomes of influenza-like illness treated with Chinese herbal medicine: an observational study Herbal medicine and pattern identification for treating COVID-19: a rapid review of guidelines Traditional Chinese medicine in the treatment of patients infected with 2019-new coronavirus (SARS-CoV-2): a review and perspective Investigating mechanism of Qingfei Dayuan granules for treatment of COVID-19 based on network pharmacology and molecular docking Study on screening potential traditional Chinese medicines against 2019-nCoV based on Mpro and PLP Chinese herbal medicine for severe acute respiratory syndrome: a systematic review and metaanalysis Traditional Chinese herbal medicine as a source of molecules with antiviral activity Can Chinese medicine be used for prevention of corona virus disease 2019 (COVID-19)? Evolving research and clinical data regarding the virologic SARS-CoV-2 suggest a potential list of repurposed drugs with appropriate pharmacological effects and therapeutic efficacies in treating COVID-19 patients.
    keywords: activity; antiviral; azithromycin; cells; clinical; coronavirus; cov-2; covid-19; disease; drugs; hydroxychloroquine; infection; influenza; lung; patients; rna; sars; study; syndrome; treatment; trial; viral
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        item: #7690 of 7819
          id: cord-354835-o0nscint
      author: Roy, Sayak
       title: Epidemiological Determinants of COVID-19-Related Patient Outcomes in Different Countries and Plan of Action: A Retrospective Analysis
        date: 2020-06-04
       words: 2469
      flesch: 41
     summary: The correlations between population characteristics and socioeconomic variables in various countries as discussed earlier with respect to outcome in terms of total positive cases and fatality rate due to COVID-19 are summarized in Table 2 . R-value P-value There is a strong positive correlation between GDP expense on the health of a country with the number of cases getting detected. The correlation coefficient was calculated by plotting dependant variables - the number of COVID-19 cases and the number of deaths due to COVID 19 on the Y-axis and independent variables - critical-care beds per capita, the median age of the population of the country, the number of COVID-19 tests per million population, population density (persons per square km), urban population percentage, and gross domestic product (GDP) expense on health care - on the X-axis.
    keywords: cases; countries; covid-19; number; population
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        item: #7691 of 7819
          id: cord-354861-b04ch0o3
      author: Nasir, E. F.
       title: Study of the Sudanese perceptions of COVID-19: Applying the Health Belief Model.
        date: 2020-05-29
       words: 4820
      flesch: 44
     summary: The HBM is health behaviour focused, and there is evidence that the effectiveness of interventions to promote health behaviour change and improve health outcomes could depend on the use of models like the HBM (16) . Five items measured self-efficacy towards health COVID-19; maintaining good health is an important part of my life and I think I am a person who cares well for his general health.
    keywords: barriers; benefits; covid-19; health; hygiene; license; medrxiv; preprint
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        item: #7692 of 7819
          id: cord-354866-5yzalrri
      author: Esenwa, Charles
       title: The effect of COVID-19 on stroke hospitalizations in New York City
        date: 2020-07-13
       words: 1534
      flesch: 49
     summary: During the pandemic period, the slope was -4.4 (se = 1.00); i.e., the number of stroke admissions decreased an average of 4.4 per week, (p = 0.005), with weekly admissions averaging 23, a reduction of 44% versus baseline. We summarize acute stroke cases by age, sex, race/ethnicity.
    keywords: acute; admissions; covid-19; stroke
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        item: #7693 of 7819
          id: cord-354885-fkgr2o9i
      author: Hoffer-Hawlik, Michael A.
       title: Leveraging Telemedicine for Chronic Disease Management in Low- and Middle-Income Countries During Covid-19
        date: 2020-09-15
       words: 1548
      flesch: 38
     summary: Health care systems which use electronic health records are well suited to telemedicine, as clinicians can access patient files remotely. Although there has been attention to the accelerated growth of telemedicine in the United States and other high-income countries, the telemedicine revolution may have an even greater benefit in LMICs, where it could improve health care access for vulnerable and geographically remote patients.
    keywords: care; covid-19; health; lmics; patients; telemedicine
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        item: #7694 of 7819
          id: cord-354888-448eqhg8
      author: Irarrázaval, María J.
       title: Telemedicine for postoperative follow-up, virtual surgical clinics during COVID-19 pandemic
        date: 2020-11-02
       words: 2858
      flesch: 44
     summary: Due to the current context and the urgent need to maintain social distance, reorganize human resources and keep patients away from clinical areas; our gastrointestinal surgery team implemented a contingency strategy based on telemedicine for postoperative patient care. On the first month of COVID era 70% of the patients preferred in-person followup but this decreased to 40% in the last month of this study, with most patients favoring telemedicine postoperative care (Fig. 3) .
    keywords: follow; patients; person; surgery; telemedicine; work
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        item: #7695 of 7819
          id: cord-354900-bzv4yhqi
      author: Jawhara, Samir
       title: How to boost the immune defence prior to respiratory virus infections with the special focus on coronavirus infections
        date: 2020-10-12
       words: 3698
      flesch: 29
     summary: Antiviral effect of Saccharomyces cerevisiae beta-glucan to swine influenza virus by increased production of interferon-gamma and nitric oxide Beta-glucan enhancement of T cell IFNgamma response in swine beta-Glucan derived from Aureobasidium pullulans is effective for the prevention of influenza in mice Effects of beta-1,3-glucan (AletaTM) on vaccination response in broiler chickens Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise Baker's yeast beta-glucan supplement reduces upper respiratory symptoms and improves mood state in stressed women Regulation of innate immune response to Candida albicans infections by alphaMbeta2-Pra1p interaction Immune recognition of fungal beta-glucans Short fungal fractions of beta-1,3 glucans affect platelet activation Clinical characteristics of coronavirus disease 2019 in China Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy ISTH interim guidance on recognition and management of coagulopathy in COVID-19 Single-cell analysis of two severe COVID-19 patients reveals a monocyte-associated and tocilizumab-responding cytokine storm Effects of 10-day confinement on the immune system and psychological aspects in humans Anti-stress action of several orally-given betaglucans Anti-stress action of an orally-given combination of resveratrol, beta-glucan, and vitamin C Effects of glucan and vitamin D supplementation on obesity and lipid metabolism in diabetic retinopathy Effects of beta-glucan and Vitamin D supplementation on inflammatory parameters in patients with diabetic retinopathy Modulation of liver fibrosis and pathophysiological changes in mice infected with Mesocestoides corti (M. vogae) after administration of glucan and liposomized glucan in combination with vitamin C Combination of glucan, resveratrol and vitamin C demonstrates strong anti-tumor potential Synergistic potentiation of D-fraction with vitamin C as possible alternative approach for cancer therapy Randomized trial of vitamin D supplementation to prevent seasonal influenza A in schoolchildren Epidemic influenza and vitamin D Vitamin D decreases respiratory syncytial virus induction of NF-kappaBlinked chemokines and cytokines in airway epithelium while maintaining the antiviral state Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes The effectiveness of vitamin C in preventing and relieving the symptoms of virus-induced respiratory infections Antiviral effect of flavonoids on human viruses Effect of increasing fruit and vegetable intake by dietary intervention on nutritional biomarkers and attitudes to dietary change: a randomised trial Roles of flavonoids against coronavirus infection Early nutritional supplementation in non-critically ill patients hospitalized for the, 2019 novel coronavirus disease (COVID-19): rationale and feasibility of a shared pragmatic protocol Effect of single-dose injection of vitamin D on immune cytokines in ulcerative colitis patients: a randomized placebo-controlled trial Regulation of cytokine responses by seasonality of vitamin D status in healthy individuals Evidence that Vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths Vitamin D insufficiency as a potential culprit in critical COVID-19 patients A new clinical trial to test high-dose vitamin C in patients with COVID-19 Protective role of 1,25(OH)2 vitamin D3 in the mucosal injury and epithelial barrier disruption in DSS-induced acute colitis in mice Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites Antiinfluenza virus effects of both live and non-live Lactobacillus acidophilus L-92 accompanied by the activation of innate immunity The gut-lung axis in respiratory disease Influenza virus affects intestinal microbiota and secondary Salmonella infection in the gut through type I interferons Management of corona virus disease-19 (COVID-19): the Zhejiang experience. Sensing of viral RNA by host receptors activates downstream signalling pathways that lead to the induction of immune responses by producing inflammatory cytokines including type I interferon (IFN) and other mediators [19] .
    keywords: covid-19; glucan; gut; infections; patients; response; virus; vitamin
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        item: #7696 of 7819
          id: cord-354902-t9df8vhc
      author: Kearns, Donovan G.
       title: Assessing the risk of dupilumab use for atopic dermatitis during the COVID-19 pandemic
        date: 2020-06-10
       words: 592
      flesch: 37
     summary: key: cord-354902-t9df8vhc authors: Kearns, Donovan G.; Uppal, Shelley; Chat, Vipawee S.; Wu, Jashin J. title: Assessing the risk of dupilumab use for atopic dermatitis during the COVID-19 pandemic date: 2020-06-10 journal: J Am Acad Dermatol DOI: 10.1016/j.jaad.2020.06.015 sha: doc_id: 354902 cord_uid: t9df8vhc nan In the midst of the COVID-19 pandemic, physicians are using what's known of the SARS-CoV-2 2 virus to establish practice guidelines for dermatologic conditions, particularly in regard to the 3 use of immunosuppressive medications. Given that IL-13 4 and IL-13 are significant in orchestrating and maintaining adaptive immunity, we sought to 14 identify and address the risks associated with dupilumab use during the COVID-19 pandemic.
    keywords: dupilumab; patients
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        item: #7697 of 7819
          id: cord-354928-brliql4d
      author: Wang, Jian
       title: Overweight and obesity are risks factors of severe illness in patients with COVID‐19
        date: 2020-07-31
       words: 2410
      flesch: 50
     summary: This study aimed to investigate the clinical features of COVID-19 patients with overweight and obesity in a multi-center cohort of COVID-19 in Jiangsu province, China. All rights reserved The associated factors of respiratory failure in COVID-19 patients were analyzed by cox regression analysis ( Overweight and obesity are serious global health problems (19, 20) .
    keywords: article; covid-19; obesity; overweight; patients; risk
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        item: #7698 of 7819
          id: cord-354936-do0bmpxt
      author: Chatterjee, Ranit
       title: COVID-19 Risk Assessment Tool: Dual application of risk communication and risk governance
        date: 2020-06-02
       words: 6219
      flesch: 54
     summary: Health risk assessment tools have been developed to assess individual risk for particular diseases. In comparison to the Arogya Setu App by Government of India, the COVID-19 Risk assessment tool, provides awareness information in the form of questions which are also used to assess the risk based on behaviour and social compliance.
    keywords: assessment; assessment tool; behaviour; coefficient; correlation; covid-19; data; health; people; risk; risk assessment; tool
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        item: #7699 of 7819
          id: cord-354939-lon10s7z
      author: Singh, S.
       title: ZINC SUFFICIENCY STATUS AND COVID-19 MORTALITY IN SOCIALLY SIMILAR EUROPEAN POPULATIONS - AN EPIDEMIOLOGICAL TIME-SERIES ANALYSIS
        date: 2020-11-05
       words: 1612
      flesch: 35
     summary: Among the analyzed countries, elevated 9X mortality risk was observed for populations with >92.5 % Zn sufficiency levels at all times as compared to populations with lower Zn sufficiency. Though the variable responsible for the observed association remains unknown, we may conjure that the increased mortality observed in high Zn sufficiency populations could be contributed by the existing certain small percentage of populations with underlying conditions as a result of altered genetic composition, physiology, response to Zn supplementations/modulation [4, 5] making them prone to display characteristic COVID-19 adverse illness as a result of increased oxygen radical generation or compromised diminished oxidative stress handling system due to their physiologies propensity to promote the pro-oxidant role of Zn on supplementation [14] .
    keywords: covid-19; mortality; populations; sufficiency
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        item: #7700 of 7819
          id: cord-354941-0ocsf255
      author: Amorin‐Woods, Deisy
       title: Family Therapy and COVID‐19: International Reflections during the Pandemic from Systemic Therapists across the Globe
        date: 2020-06-08
       words: 10005
      flesch: 56
     summary: Family therapists, paradoxically, given the core of their work is with systems, are also experiencing upheaval in professional and personal lives, trying to work amidst a society in chaos. I realised this was a global crisis; a collective narrative unfolding daily which has left no one untouched, and we as family therapists had important and individual stories to tell.
    keywords: covid-19; experience; families; family; fear; life; look; need; new; pandemic; people; social; system; therapists; therapy; time; trauma; virus; way; world
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        item: #7701 of 7819
          id: cord-354943-wxhbwcfr
      author: Guo, Li
       title: Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19)
        date: 2020-03-21
       words: 3497
      flesch: 52
     summary: To evaluate the potential cross-reactivities of N proteins between SARS-CoV-2 and other human coronaviruses, we examined the reactivities of the SARS-CoV-2 rNP and human plasma with positive antibodies against NL63, 229E, OC43, HKU1, and SARS-CoV, respectively, by using Western blot and ELISA assays. Novel coronavirus (2019-nCoV) early-stage importation risk to Europe Summary of probable SARS cases with onset of illness from 1 Acknowledgments.
    keywords: coronavirus; cov-2; days; detection; igm; patients; samples; sars
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        item: #7702 of 7819
          id: cord-354959-0iwdqbu6
      author: Saddik, B.
       title: Increased levels of anxiety among medical and non-medical university students during the COVID-19 pandemic in the United Arab Emirates.
        date: 2020-05-13
       words: 3829
      flesch: 47
     summary: Non-medical students reported higher levels of anxiety before and after online learning in 308 comparison to medical students and whilst medical student anxiety levels decreased following the 309 introduction of online learning, non-medical student's anxiety levels increased. Non-medical students exercised higher compliance with social restrictions, while medical students practiced better hand hygiene.
    keywords: anxiety; covid-19; levels; license; preprint; students
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        item: #7703 of 7819
          id: cord-354972-nc496v6s
      author: Margolin, Emmanuel
       title: Prospects for SARS-CoV-2 diagnostics, therapeutics and vaccines in Africa
        date: 2020-09-10
       words: 10934
      flesch: 27
     summary: The host immune response in respiratory virus infection: balancing virus clearance and immunopathology Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection Disappearance of antibodies to SARS-associated coronavirus after recovery Two-year prospective study of the humoral immune response of patients with severe acute respiratory syndrome Positive RT-PCR test results in patients recovered from COVID-19 Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus Immunization with inactivated Middle East respiratory syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge Molecular mechanism for antibodydependent enhancement of coronavirus entry Medical countermeasures analysis of 2019-nCoV and vaccine risks for antibody-dependent enhancement (ADE) Several strategies may improve the magnitude and durability of vaccine responses in individuals infected with HIV-1, such as higher doses, booster immunizations and/or the use of adjuvants 127 .
    keywords: africa; cases; coronavirus; countries; cov-2; covid-19; development; disease; individuals; infection; pandemic; patients; responses; risk; sars; south; spike; testing; trial; tuberculosis; vaccine; virus
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        item: #7704 of 7819
          id: cord-354989-k0qktzor
      author: Mantica, Guglielmo
       title: NON-COVID-19 VISITS TO EMERGENCY DEPARTMENTS DURING THE PANDEMIC: THE IMPACT OF FEAR
        date: 2020-05-07
       words: 521
      flesch: 40
     summary: Italy saw an exponential growth in COVID-19 cases from the day the first patient was identified in the North of Italy until the 9th of March, when the Italian government imposed the national lockdown. We compared ED visits in two major referral hospitals in the North of Italy from the 21st February to 16th April with COVID-19 daily mortality data from the Italian Civil Protection Department 4 (see Figure 1 ).
    keywords: covid-19; visits
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        item: #7705 of 7819
          id: cord-354993-gdz63spj
      author: Larcher, Victor
       title: Children of COVID-19: pawns, pathfinders or partners?
        date: 2020-06-05
       words: 1955
      flesch: 47
     summary: COVID-19 seems to have, at least initially, affected children less severely than adults with <2% of infected children needing critical care and mercifully few deaths. key: cord-354993-gdz63spj authors: Larcher, Victor; Brierley, Joe title: Children of COVID-19: pawns, pathfinders or partners? date: 2020-06-05 journal: J Med Ethics DOI: 10.1136/medethics-2020-106465 sha: doc_id: 354993 cord_uid: gdz63spj Countries throughout the world are counting the health and socioeconomic costs of the COVID-19 pandemic, including the strategies necessary to contain it.
    keywords: adults; children; covid-19; health; recovery
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        item: #7706 of 7819
          id: cord-355001-audh5qa7
      author: Novick, Tessa K.
       title: COVID-19 and Kidney Disease Disparities in the United States
        date: 2020-06-23
       words: 3578
      flesch: 42
     summary: The economic impact of the pandemic has had a disproportionate effect on women, minorities and immigrants, which may limit their ability to manage kidney disease, and lead to complications or kidney disease progression. A study in San Francisco found that chronic kidney disease patients experiencing homelessness have higher acute care utilization than stably housed counterparts, and greater exposure to hospitals increases COVID-19 exposure.
    keywords: care; covid-19; dialysis; disease; immigrants; kidney; patients; risk
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        item: #7707 of 7819
          id: cord-355015-e681jmix
      author: Cici, Remziye
       title: Determination of anxiety levels and perspectives on the nursing profession among candidate nurses with relation to the COVID‐19 pandemic
        date: 2020-08-10
       words: 1833
      flesch: 47
     summary: High scores indicate high anxiety levels. The total score obtained from the scale varies between 0 and 63, and high scores are representative of high anxiety levels.
    keywords: anxiety; covid-19; nursing; pandemic; profession
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        item: #7708 of 7819
          id: cord-355023-68lp7i5v
      author: Rishi, Praveen
       title: Diet, Gut Microbiota and COVID-19
        date: 2020-09-28
       words: 5799
      flesch: 32
     summary: Front Nutr 6:188 Better management of alcohol liver disease using a 'microstructured synbox' system comprising L. plantarum and EGCG Polyphenols-gut microbiota interplay and brain neuromodulation Role of dietary nutrients in the modulation of gut microbiota: a narrative review Dietary zinc alters the microbiota and decreases resistance to Clostridium difficile infection Food combination based on a pre-hispanic Mexican diet decreases metabolic and cognitive abnormalities and gut microbiota dysbiosis caused by a sucroseenriched high-fat diet in rats ACE2 imbalance as a key player for the poor outcomes in COVID-19 patients with agerelated comorbidities-role of gut microbiota dysbiosis Comparison of DNA extraction methods for optimal recovery of metagenomic DNA from human and environmental samples The human gut microbiota: Believing the notion: ' We are, what we eat', this manuscript provides an opportunity to the researchers in the field of Microbiology and Medical health to carry out studies on the effect of forced fasting on gut microbiota and means to counter any potential ill effects.
    keywords: countries; covid-19; diet; disease; food; gut; health; india; inflammation; lockdown; microbiota; population
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        item: #7709 of 7819
          id: cord-355028-1x7w1749
      author: Piazza, Cesare
       title: Long-term intubation and high rate of tracheostomy in COVID-19 patients might determine an unprecedented increase of airway stenoses: a call to action from the European Laryngological Society
        date: 2020-06-06
       words: 4323
      flesch: 27
     summary: key: cord-355028-1x7w1749 authors: Piazza, Cesare; Filauro, Marta; Dikkers, Frederik G.; Nouraei, S. A. Reza; Sandu, Kishore; Sittel, Christian; Amin, Milan R.; Campos, Guillermo; Eckel, Hans E.; Peretti, Giorgio title: Long-term intubation and high rate of tracheostomy in COVID-19 patients might determine an unprecedented increase of airway stenoses: a call to action from the European Laryngological Society date: 2020-06-06 journal: Eur Arch Otorhinolaryngol DOI: 10.1007/s00405-020-06112-6 sha: doc_id: 355028 cord_uid: 1x7w1749 INTRODUCTION: COVID-19 patients admitted to the ICU often require prolonged mechanical ventilation with high positive endexpiratory pressure through an endotracheal tube, with a frequency reported as high as 88% in a series of 1591 consecutive patients treated at 72 hospitals included in the COVID-19 Lombardy ICU Network, Italy
    keywords: airway; conditions; covid-19; endotracheal; icu; intubation; laryngotracheal; lts; patients; stenosis; tracheostomy
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        item: #7710 of 7819
          id: cord-355031-l0tj7kp2
      author: Krenitsky, Nicole M.
       title: Primed for a Pandemic: Implementation of Telehealth Outpatient Monitoring for Women with Mild COVID-19
        date: 2020-07-21
       words: 3004
      flesch: 37
     summary: key: cord-355031-l0tj7kp2 authors: Krenitsky, Nicole M.; Spiegelman, Jessica; Sutton, Desmond; Syeda, Sbaa; Moroz, Leslie title: Primed for a Pandemic: Implementation of Telehealth Outpatient Monitoring for Women with Mild COVID-19 date: 2020-07-21 journal: Semin Perinatol DOI: 10.1016/j.semperi.2020.151285 sha: doc_id: 355031 cord_uid: l0tj7kp2 Close observation and rapid escalation of care is essential for obstetric patients with COVID-19. We describe the experience and lessons learned while designing and implementing a virtual telemonitoring COVID-19 clinic for obstetric patients.
    keywords: care; clinic; covid-19; monitoring; patients; providers; telehealth; visits
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        item: #7711 of 7819
          id: cord-355039-qi4fwqbc
      author: Azar, William S.
       title: COVID-19 and diabetes mellitus: how one pandemic worsens the other
        date: 2020-08-02
       words: 7376
      flesch: 37
     summary: A more favorable SARS-CoV-2 binding was demonstrated with increased ACE2 expression in alveolar AT2 cells, as well as in the myocardium, kidneys, and pancreas in humans The genome-wide association study (GWAS) on patients with type 2 diabetes (N = 898,130) revealed that type 2 diabetes is causally linked to increased ACE2 expression.
    keywords: ace2; ampk; angiotensin; coronavirus; cov-2; covid-19; cytokine; diabetes; disease; expression; il-6; infection; mtor; patients; protein; sars
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        item: #7712 of 7819
          id: cord-355047-ri43d5wk
      author: Sarangi, Bhakti
       title: Epidemiological and Clinical Characteristics of COVID-19 in Indian Children in the Initial Phase of the Pandemic
        date: 2020-07-28
       words: 1800
      flesch: 53
     summary: • Majority of Indian children with SARS-CoV-2 infection had a mild course of disease during the initial stages of the pandemic COVID-19 IN INDIAN CHILDREN www.who.int/publications-detail/global-surveillance-forhuman-infection-with-novel-coronavirus Park's Textbook of Preventive and Social Medicine Centers for Disease Control and Prevention Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: An observational cohort study Clinical features and outcome of SARS-CoV-2 infection in children: A systematic review and meta-analysis COVID-19: Data Summary -NYC Health SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor Prevalence of malnutrition and analysis of related factors in elderly patients with COVID-19 in Wuhan, China Neutrophil-to-lymphocyte ratio and lymphocyte-to-C-reactive protein ratio in patients with severe coronavirus disease 2019 (COVID-19): A metaanalysis C-reactive protein levels in the early stage of COVID-19 Potentials and limitations of molecular diagnostic methods in food safety Predicting infectious SARS-CoV-2 from diagnostic samples All children between one month and 18 years of age who tested positive by the RT-PCR technique for nasopharyngeal swab were included in the study -these also included asymptomatic children as per the management guidelines in force.
    keywords: children; covid-19; disease; majority; study
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        item: #7713 of 7819
          id: cord-355074-u5s3uzp6
      author: Bamgboye, Ebun L.
       title: COVID-19 Pandemic: Is Africa Different?
        date: 2020-11-03
       words: 3831
      flesch: 49
     summary: Case numbers, mortality, number of tests performed, and demographic data were summarized and compared by continents, regions, and countries within the continent of Africa. The busiest international airports in the continent are located in South Africa which also has the highest numbers on the continent, followed by Egypt which is also second in case numbers ( Figure 4A ).
    keywords: africa; cases; continent; countries; covid-19; disease; mortality; patients
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        item: #7714 of 7819
          id: cord-355080-bzax1u33
      author: Atkins, J. L.
       title: PREEXISTING COMORBIDITIES PREDICTING SEVERE COVID-19 IN OLDER ADULTS IN THE UK BIOBANK COMMUNITY COHORT
        date: 2020-05-08
       words: 2793
      flesch: 43
     summary: key: cord-355080-bzax1u33 authors: Atkins, J. L.; Masoli, J. A.; Delgado, J.; Pilling, L. C.; Kuo, C.-L. C.; Kuchel, G.; Melzer, D. title: PREEXISTING COMORBIDITIES PREDICTING SEVERE COVID-19 IN OLDER ADULTS IN THE UK BIOBANK COMMUNITY COHORT date: 2020-05-08 journal: nan DOI: 10.1101/2020.05.06.20092700 sha: doc_id: 355080 cord_uid: bzax1u33 Background: Older COVID-19 hospitalized patients frequently have hypertension, diabetes or coronary heart disease (CHD), but whether these are more common than in the population is unclear. There were 274,356 participants aged 65+, including 448 (0.16%) hospitalized COVID-19 patients.
    keywords: covid-19; disease; license; medrxiv; patients; preprint
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        item: #7715 of 7819
          id: cord-355102-jcyq8qve
      author: Avila, Eduardo
       title: Hemogram data as a tool for decision-making in COVID-19 management: applications to resource scarcity scenarios
        date: 2020-06-29
       words: 4771
      flesch: 34
     summary: Also, our simulations suggest that the NB model has at least some degree of tolerance to missing data values, which can be advantageous when compared to other ML techniques. The Naïve Bayes (NB) method combines the previous probability of an event (also called prior probability, or simply prior) with additional evidence (as, e.g., a set of clinical data from a patient) to calculate a combined, conditional probability that includes the prior probability given the extra information.
    keywords: covid-19; data; hemogram; model; patients; pcr; prior; probability; results
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        item: #7716 of 7819
          id: cord-355115-oa0okey8
      author: Odedra, Devang
       title: Impact of COVID-19 on Canadian Radiology Residency Training Programs
        date: 2020-06-11
       words: 3112
      flesch: 45
     summary: In this study, we surveyed Canadian radiology residents to understand the impact of the pandemic on their residency training, strategies utilized by the residency programs in mitigating those impacts, and factors important to residents in the selection of educational resources on COVID-19. In this study, we aimed to survey Canadian radiology residents on the impact of COVID-19 on their residency training by means of a web-based questionnaire.
    keywords: canadian; covid-19; impact; pandemic; programs; radiology; residents; training
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        item: #7717 of 7819
          id: cord-355122-x3v80bdp
      author: Desterke, Christophe
       title: PPARγ cistrome repression during activation of lung monocyte-macrophages in severe COVID-19
        date: 2020-09-25
       words: 7901
      flesch: 31
     summary: Overall, these results demonstrate for the first time, the involvement of the PPARγ complex in severe COVID-19 lung disease and suggest strongly its role in the major monocyte / macrophage-mediated inflammatory storm. We identified a correlation with the disease severity and the reduced expression of several members of the PPARγ complex such as EP300, RXRA, RARA, SUMO1, NR3C1, CCDC88A. CHIP-seq analyses confirmed repression of the PPARγ-RXRA-NR3C1 cistrome in COVID-19 lung samples.
    keywords: analysis; cell; covid-19; covid-19 lung; data; disease; expression; figure; gene; immune; lung; macrophages; patients; pparγ; receptor; response; samples; supplemental; transcriptome
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        item: #7718 of 7819
          id: cord-355131-ushv3n0z
      author: Giuffrè, Mauro
       title: COVID-19-Induced Thrombosis in Patients without Gastrointestinal Symptoms and Elevated Fecal Calprotectin: Hypothesis Regarding Mechanism of Intestinal Damage Associated with COVID-19
        date: 2020-09-16
       words: 1457
      flesch: 38
     summary: [5] proposed the role of fecal calprotectin (FC) as a marker of intestinal inflammation in COVID-19 patients who developed gastrointestinal (GI) symptoms. In non-COVID-19 patients, left flexure and sigmoid colon segments have the highest risk of ischemic colitis, while distal rectum is usually spared due to its dual blood supply; at variance, in COVID-19 patients colon/rectal thickening was previously reported in seven cases [13] in agreement with our data, supporting a relationship between intestinal damage and COVID-19 infection.
    keywords: covid-19; patients; symptoms
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        item: #7719 of 7819
          id: cord-355146-6rat5j64
      author: Whittemore, Paul
       title: Use of awake proning to avoid invasive ventilation in a patient with severe COVID-19 pneumonitis
        date: 2020-08-03
       words: 1335
      flesch: 46
     summary: In a recent pilot of awake proning in patients with COVID-19 at one New York emergency department, the median SpO 2 improved from 84% to 94%. Once the pandemic has abated, there may be a role for awake proning in patients with other respiratory illness/infection who are proving difficult to oxygenate in the more conventional supine position, though further studies are required to validate it as an effective treatment.
    keywords: covid-19; oxygen; patients; proning
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        item: #7720 of 7819
          id: cord-355155-1k48jx7v
      author: Harper, L.
       title: The impact of covid-19 on research
        date: 2020-07-09
       words: 1045
      flesch: 41
     summary: The multinational support rapidly infused for COVID-19 research is in the billions of euros 2 . Furthermore, research funding that relies on public fundraising is expected to drop substantially and many researchers will see a significant decrease in funding opportunities 13 .
    keywords: covid-19; pandemic; research
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        item: #7721 of 7819
          id: cord-355173-rnley2ow
      author: Ibrahim, R. R.
       title: Forecasting the spread of COVID-19 in Nigeria using Box-Jenkins Modeling Procedure
        date: 2020-05-08
       words: 3756
      flesch: 47
     summary: Use of time-series analysis in infectious disease surveillance-bulletin of the World Health Organization Genomic Characterization of Severe Acute Respiratory Syndrome-Related Coronavirus in European Bats and Classification of Coronaviruses Based on Partial RNA-Dependent RNA Polymerase Gene Sequences Prediction of Incidence of Notifiable Contagious Diseases by Appalication of Time Series Model Forecasting incidence of intestinal infectious diseases in mainland China with ARIMA model and GM (1, 1) model Comparison of ARIMA and Random Forest time series models for prediction of avian influenza H5N1 outbreaks Predicting the incidence of hand, foot and mouth disease in Sichuan province, China using the ARIMA model Forecasting incidence of hemorrhagic fever with renal syndrome in China using ARIMA model Malaria disease distribution in Sudan using time series ARIMA model Coronavirus disease 2019. Overall, we were able to formulate time series models on the spread of COVID-19 in Nigeria, conduct a diagnostic check on the models formulated to determine the most suitable model, Estimate the parameters of the various models and forecast the COVID-19 spread variable.
    keywords: arima; cases; covid-19; february; model; nigeria; series; spread; trend
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        item: #7722 of 7819
          id: cord-355175-uo9fx6jy
      author: Ferrazzi, E
       title: Vaginal delivery in SARS‐CoV‐2‐infected pregnant women in Northern Italy: a retrospective analysis
        date: 2020-05-28
       words: 3188
      flesch: 46
     summary: Most deliveries of infected women occurred in the designated COVID-19 hubs, but some were delivered in special hospitals because they were Criteria for entry to the study were: Pregnant women who delivered during the study period with a confirmed diagnosis of COVID-19 infection prior to or within 36 hours after delivery. (42.9%, 95% CI 27.7-59.0) cases: in eight cases the indication was unrelated to COVID-19 infection.
    keywords: cases; covid-19; delivery; infection; transmission; women
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        item: #7723 of 7819
          id: cord-355181-affuyn8z
      author: Poggio, Claudio
       title: Copper-Alloy Surfaces and Cleaning Regimens against the Spread of SARS-CoV-2 in Dentistry and Orthopedics. From Fomites to Anti-Infective Nanocoatings
        date: 2020-07-22
       words: 5801
      flesch: 38
     summary: Exposure to copper surfaces results in morphological changes to human coronavirus particles visible in transmission electron microscopy (TEM) [67] . Given this context, the use of copper surfaces brings a new perspective for constant and inherent disinfection.
    keywords: alloy; copper; coronavirus; cov-2; covid-19; infection; metal; nanoparticles; sars; spread; surfaces; virus
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        item: #7724 of 7819
          id: cord-355186-7u4h083p
      author: Kobak, Senol
       title: Comment on “Colchicine may not be effective in COVID-19 infection; it may even be harmful?”
        date: 2020-06-20
       words: 693
      flesch: 45
     summary: key: cord-355186-7u4h083p authors: Kobak, Senol title: Comment on “Colchicine may not be effective in COVID-19 infection; it may even be harmful?” date: 2020-06-20 journal: Clin Rheumatol DOI: 10.1007/s10067-020-05233-x sha: doc_id: 355186 cord_uid: 7u4h083p nan We read with great interest the report by Cure et al. which speculated that colchicine may not be effective in COVID-19 infection Also, they suggest that colchicine may increase the risk of acute respiratory distress syndrome(ARDS) and disseminated intravascular coagulation(DIC) which may occur during COVID-19 infection.
    keywords: colchicine; covid-19
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        item: #7725 of 7819
          id: cord-355192-80f2658b
      author: Owen, Rhiannon K
       title: Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using electronic health records
        date: 2020-07-17
       words: 4610
      flesch: 43
     summary: Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Similarity in case fatality rates (CFR) of COVID-19/SARS-COV-2 in Italy and China Clinical Guidance: Assessing Whether COVID-19 Patients will Benefit from Critical Care, and an Objective Approach to Capacity Challenges Management of frailty: opportunities, challenges, and future directions Frailty in very old critically ill patients in Australia and New Zealand: a populationbased cohort study e contribution of frailty, cognition, activity of daily life and comorbidities on outcome in acutely admitted patients over 80 years in European ICUs: the VIP2 study Does the clinical frailty score improve the accuracy of the SOFA score in predicting hospital mortality in elderly critically ill patients? For the purposes of this study, older people were assigned into six frailty categories reflecting the full spectrum of frailty rather than the dichotomous frail versus not frail approach used in previous critical care studies [7] [8] [9] [10] [11] : • CFS 1-3: fit-managing well • CFS 4-5: vulnerable/mild frailty • CFS 6: moderate frailty • CFS 7-8: severely to very severely frail • CFS 9: terminally ill; life expectancy <6 months, but not otherwise evidently frail • CFS not recorded: missing We also reported outcomes using the CFS as a dichotomous predictor (CFS <5 versus ≥5), reflecting the NICE critical care guidance [12] .
    keywords: care; cfs; covid-19; frailty; hazard; hospital; mortality; outcomes; people; study
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        item: #7726 of 7819
          id: cord-355208-hpldjsc5
      author: Leisman, Daniel E.
       title: Facing COVID-19 in the ICU: vascular dysfunction, thrombosis, and dysregulated inflammation
        date: 2020-04-28
       words: 1418
      flesch: 31
     summary: COVID-19 patients develop profound hypoxemia early in their disease course. Importantly, admission AngII levels in COVID-19 patients are reportedly twice the normal levels [13] .
    keywords: angii; covid-19; endothelial; patients; vascular
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        item: #7727 of 7819
          id: cord-355218-eici4eit
      author: Punn, Narinder Singh
       title: Automated diagnosis of COVID-19 with limited posteroanterior chest X-ray images using fine-tuned deep neural networks
        date: 2020-10-17
       words: 5954
      flesch: 42
     summary: Covid-caps: a capsule network-based framework for identification of covid-19 cases from x-ray images Eosinophilic lung diseases Covid-19: automatic detection from x-ray images utilizing transfer learning with convolutional neural networks The diagnostic evaluation of convolutional neural network (cnn) for the assessment of chest x-ray of patients infected with covid-19 Adaptive total variation denoising based on difference curvature Deep learning-based image conversion of ct reconstruction kernels improves radiomics reproducibility for pulmonary nodules or masses A novel transfer learning based approach for pneumonia detection in chest x-ray images Covid-19 image data collection Imagenet: a large-scale hierarchical image database Covid-resnet: a deep learning framework for screening of covid19 from radiographs Deep learning in medical image analysis: a third eye for doctors Low-light image enhancement of high-speed endoscopic videos using a convolutional neural network The origin, transmission and clinical therapies on coronavirus disease 2019 (covid-19) outbreak-an update on the status Finding covid-19 from chest x-rays using deep learning on a small dataset Computer Vision: A Reference Guide Deep residual learning for image recognition Densely connected convolutional networks Chexpert: a large chest radiograph dataset with uncertainty labels and expert comparison Two public chest x-ray datasets for computer-aided screening of pulmonary diseases Using deep learning to detect pneumonia caused by ncov-19 from x-ray images Survey on deep learning with class imbalance Identifying medical diagnoses and treatable diseases by image-based deep learning Detection of coronavirus (covid-19) associated pneumonia based on generative adversarial networks and a fine-tuned deep transfer learning model using chest x-ray dataset Loss functions in classification tasks Imagenet classification with deep convolutional neural networks Deep learning at chest radiography: automated classification of pulmonary tuberculosis by using convolutional neural networks A transfer learning method with deep residual network for pediatric pneumonia diagnosis A survey of deep neural network architectures and their applications Differentiable learning-to-normalize via switchable normalization The forthcoming artificial intelligence (ai) revolution: its impact on society and firms Automatic detection of coronavirus disease (covid-19) using x-ray images and deep convolutional neural networks Chexnet: an in-depth review Deep learning covid-19 features on cxr using limited training data sets Image thresholding Deep anomaly detection with deviation networks Covid-19 posteroanterior chest x-ray fused (cpcxr) dataset Inception u-net architecture for semantic segmentation to identify nuclei in microscopy cell images Covid-19 epidemic analysis using machine learning and deep learning algorithms medRxiv Harmony-search and otsu based system for coronavirus disease (covid-19) detection using lung ct scan images Deep learning for chest radiograph diagnosis: a retrospective comparison of the chexnext algorithm to practicing radiologists Explaining the predictions of any classifier U-net: convolutional networks for biomedical image segmentation An overview of gradient descent optimization algorithms Classification of images of childhood pneumonia using convolutional neural networks Grad-cam: visual explanations from deep networks via gradient-based localization Detection of coronavirus disease (covid-19) based on deep features Deep learning in medical image analysis Deep inside convolutional networks: visualising image classification models and saliency maps Very deep convolutional networks for large-scale image recognition Pneumonia dataset annotation methods. COVID-19 image dataset is a public database of pneumonia cases with CXR images related to COVID-19, MERS, SARS, and ARDS collected by Cohen et al.
    keywords: chest; classification; covid-19; cxr; dataset; images; learning; model; pneumonia; ray; samples
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        item: #7728 of 7819
          id: cord-355256-7ksbvisv
      author: Sloane, Philip D.
       title: Cruise Ships, Nursing Homes and Prisons as COVID-19 Epicenters: A ‘Wicked Problem” with Breakthrough Solutions?
        date: 2020-04-30
       words: 2732
      flesch: 49
     summary: In contrast, nursing home care is far more challenging. In New York, 72 long-term care facilities had five or more deaths each; in New Jersey, almost two-thirds of nursing homes had recorded COVID-19 infections; 3 and in Pennsylvania 55% of COVID-19 deaths were reported to have been among residents of nursing homes or personal care homes.
    keywords: care; covid-19; cruise; health; homes; nursing; term
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        item: #7729 of 7819
          id: cord-355267-ndzgxk0k
      author: Kassa, Semu M.
       title: Analysis of the mitigation strategies for COVID-19: from mathematical modelling perspective
        date: 2020-06-05
       words: 8624
      flesch: 48
     summary: key: cord-355267-ndzgxk0k authors: Kassa, Semu M.; Njagarah, John B.H.; Terefe, Yibeltal A. title: Analysis of the mitigation strategies for COVID-19: from mathematical modelling perspective date: 2020-06-05 journal: Chaos Solitons Fractals DOI: 10.1016/j.chaos.2020.109968 sha: doc_id: 355267 cord_uid: ndzgxk0k In this article, a mathematical model for the transmission of COVID-19 disease is formulated and analysed. The World Health Organization (WHO) medical team codenamed the new outbreak caused by SARS-CoV-2 as coronavirus disease 2019 (COVID- 19) .
    keywords: cases; coronavirus; covid-19; disease; individuals; infection; model; parameters
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        item: #7730 of 7819
          id: cord-355271-zynnr776
      author: Agrawal, Amit
       title: Letter to the editor– “Staying Home - Early Changes in Patterns of Neurotrauma in New York City during the COVID-19 Pandemic
        date: 2020-08-09
       words: 642
      flesch: 42
     summary: References: Staying Home An epidemiological study of traumatic brain injury cases in a trauma centre of New Delhi (India) Estimating the global incidence of traumatic brain injury A systematic review of quantitative research on traumatic brain injury in India Variation in volumes and characteristics of trauma patients admitted to a level one trauma centre during national level 4 lockdown for COVID-19 in New Zealand Impact of the COVID-19 pandemic on orthopedic trauma workload in a London level 1 trauma center: the golden month Lessons learnt from COVID 19: An Italian multicentric epidemiological study of orthopaedic and trauma services COVID-19-Impact on DNR Orders in the Largest Cancer Center in Jordan The Importance of Addressing Advance Care Planning and Decisions About Do-Not-Resuscitate Orders During Novel Coronavirus 2019 (COVID-19) Staying Home -Early Changes in Patterns of Neurotrauma in New York City during the COVID-19 Pandemic 6, 7 Furthermore, comparative reduction in the number of surgeries may be due to overall decrease in neurotrauma cases and also due to DNR (do not resuscitate) strategies in terminally sick patients.
    keywords: covid-19; neurotrauma
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        item: #7731 of 7819
          id: cord-355283-ny1ju7vc
      author: Colombo, L.
       title: How to manage thromboembolic risk in patient with SARS-CoV-2-related disease in the Emergency Department: a case report of cardiogenic shock due to massive pulmonary embolism
        date: 2020-08-12
       words: 1958
      flesch: 32
     summary: Sudden death due to acute pulmonary embolism in a young woman with COVID-19 Venous thromboembolism Incidence of thrombotic complications in critically ill ICU patients with COVID-19 High incidence of venous thromboembolic events in anticoagulated severe COVID-19 patients Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Diagnosis and management of sepsis-induced coagulopathy and disseminated intravascular coagulation Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging Imaging of acute pulmonary embolism: an update. Considering the high prevalence of thromboembolic events in COVID-19 patients it is mandatory for the emergency physician to systematically evaluate signs of pulmonary thromboembolism, in order to perform the most patient-tailored therapy as soon as possible.
    keywords: acute; covid-19; embolism; patients; sars
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        item: #7732 of 7819
          id: cord-355292-n6sq2jz9
      author: Chen, Yan
       title: Infants Born to Mothers With a New Coronavirus (COVID-19)
        date: 2020-03-16
       words: 2628
      flesch: 53
     summary: Typical CT images of COVID-19 infection with ground glass changes were presented in these pregnant patients. Throughout the clinical course, there were no manifestations or radiologic, hematologic, or biochemical evidence suggestive of COVID-19 infection.
    keywords: case; coronavirus; covid-19; infants; infection; women
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        item: #7733 of 7819
          id: cord-355294-gifsqph6
      author: García-Suárez, Julio
       title: Impact of hematologic malignancy and type of cancer therapy on COVID-19 severity and mortality: lessons from a large population-based registry study
        date: 2020-10-08
       words: 4738
      flesch: 37
     summary: Patients with hematologic malignancies typically are known to have higher levels of immunosuppression and may develop more severe respiratory viral infections than patients with solid tumors. A large-scale study using UK Coronavirus Cancer Monitoring Project data gave consistent findings [9] . Patients with hematologic malignancies usually have higher levels of immunosuppression and may develop more severe respiratory viral infections than patients with solid tumors [10] .
    keywords: cancer; covid-19; data; disease; hematologic; malignancies; mortality; patients; severity; study; therapy
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        item: #7734 of 7819
          id: cord-355296-46jf56nc
      author: Goldstein, David P.
       title: Tracheoesophageal voice prosthesis management in laryngectomy patients during the COVID-19 pandemic
        date: 2020-08-10
       words: 3057
      flesch: 42
     summary: While there is no data to suggest that tracheal and nasopharyngeal swabs will be discordant in laryngectomy patients, there are reports in the general population of COVID-19 positive patients demonstrating that nasopharyngeal swabs and tracheal aspirates can be discordant [13] . Since coronavirus is transmitted through respiratory droplets or aerosolization of virus from the upper aerodigestive tract (UADT), aerosol generating procedures (AGPs), such as those frequently performed in Otolaryngology-Head and Neck Surgery, can put health care workers at significant risk of transmission of the virus when performed in COVID-19 positive patients [4] [5] [6] .
    keywords: change; covid-19; patients; prosthesis; screening; tep; voice
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        item: #7735 of 7819
          id: cord-355311-x6cozo6b
      author: Cunningham, Conor
       title: Why physical activity matters for older adults in a time of pandemic
        date: 2020-09-23
       words: 2340
      flesch: 43
     summary: World Health Organization Worldwide trends in insufficient physical activity from 2001 to 2016: a pooled analysis of 358 populationbased surveys with 1·9 million participants The economic burden of physical inactivity: a systematic review and critical appraisal Trajectories of physical function decline and psychological functioning: the Quebec longitudinal study on nutrition and successful aging (NuAge) Physical inactivity among older adults across Europe based on the SHARE database Risk of increased physical inactivity during COVID-19 outbreak in older people: a call for actions Social impact of COVID-19 survey Older people and COVID-19: isolation, risk and ageism The psychological impact of quarantine and how to reduce it: rapid review of the evidence Consequences of physical inactivity in older adults: a systematic review of reviews and meta-analyses Effects of 3 months of detraining on functional fitness and quality of life in older adults who regularly exercise Effects of three months of detraining on the health profile of older women after a multicomponent exercise program Continuity of care and outpatient management for patients with and at high risk for cardiovascular disease during the COVID-19 pandemic: a scientific statement from the American Society for Preventive Cardiology Sanchis-Gomar F. Physical inactivity and cardiovascular disease at the time of coronavirus disease 2019 (COVID-19) key: cord-355311-x6cozo6b authors: Cunningham, Conor; O’ Sullivan, Roger title: Why physical activity matters for older adults in a time of pandemic date: 2020-09-23 journal: Eur Rev Aging Phys Act DOI: 10.1186/s11556-020-00249-3 sha: doc_id: 355311 cord_uid: x6cozo6b BACKGROUND:
    keywords: adults; covid-19; health; physical
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        item: #7736 of 7819
          id: cord-355314-2gb9pzy0
      author: Kalyanaraman Marcello, R.
       title: Characteristics and Outcomes of COVID-19 Patients in New York City's Public Hospital System
        date: 2020-06-01
       words: 4408
      flesch: 52
     summary: Reports published to date on COVID-19 patients in NYC have been of cohorts within private health systems that typically serve primarily insured, higher-income patients. COVID-19 patients were defined as those with a laboratory-confirmed positive test.
    keywords: age; covid-19; disease; medrxiv; patients; preprint
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        item: #7737 of 7819
          id: cord-355318-qm79gz8w
      author: Smit, Albertus J.
       title: Winter Is Coming: A Southern Hemisphere Perspective of the Environmental Drivers of SARS-CoV-2 and the Potential Seasonality of COVID-19
        date: 2020-08-05
       words: 15421
      flesch: 37
     summary: A systematic review and meta-analysis Effect of routine isoniazid preventive therapy on tuberculosis incidence among HIV-Infected men in South Africa Tuberculosis in sub-Saharan Africa: Opportunities, challenges, and change in the era of antiretroviral treatment Burden of HIV-associated histoplasmosis compared with tuberculosis in Latin America: A modelling study COVID-19 in HIV Investigators COVID-19 in patients with HIV: Clinical case series Maintaining HIV care during the COVID-19 pandemic Impact of COVID-19 on tuberculosis control in China COVID-19: Getting ahead of the epidemic curve by early implementation of social distancing Viral dynamics in mild and severe cases of COVID-19 Report from the American Society for Microbiology COVID-19 International Summit Delivery of infection from asymptomatic carriers of COVID-19 in a familial cluster Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals COVID-19: A need for real-time monitoring of weekly excess deaths No association of COVID-19 transmission with temperature or UV radiation in Chinese cities Impact of weather on COVID-19 pandemic in Turkey Association between ambient temperature and COVID-19 infection in 122 cities from China Modeling infectious disease dynamics in the complex landscape of global health Rt COVID-19 Renormalization group approach to pandemics: The COVID-19 case. Revista Ibero-Americana de Ciências Ambientias 2020 Gaussian approach for probability and correlation between the number of COVID-19 cases and the air pollution in Lima The role of climate during the COVID-19 epidemic in New South Wales Correlation between climate indicators and COVID-19 pandemic Correlation between weather and Covid-19 pandemic in Jakarta Effect of weather on COVID-19 spread in the US: A prediction model for India in 2020 Impact of meteorological factors on the COVID-19 transmission: A multi-city study in China The role of environmental factors on transmission rates of the COVID-19 Outbreak: An initial assessment in two spatial scales The ERA-interim reanalysis: Configuration and performance of the data assimilation system The sensitivity and specificity analyses of ambient temperature and population size on the transmission rate of the novel coronavirus (COVID-19) in different provinces in Iran Non-linear modulation of COVID-19 transmission by climate conditions Transmissibility of COVID-19 and its association with temperature and humidity Developing a machine learning framework to determine the spread of COVID-19.
    keywords: air; cases; countries; cov-2; covid-19; data; disease; hemisphere; humidity; infection; influenza; models; pandemic; rate; sars; seasonality; spread; studies; temperature; time; transmission; variables; virus
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        item: #7738 of 7819
          id: cord-355356-g7lvb8b4
      author: Lamb, Yvette N.
       title: Remdesivir: First Approval
        date: 2020-09-01
       words: 5057
      flesch: 44
     summary: In an earlier analysis of data from adults with COVID-19 treated with compassionate use remdesivir (n = 53), the overall rate of clinical improvement was 68% after a median follow-up of 18 days [44] . Among pregnant women (n = 67) and postpartum women (n = 19) who received compassionate use remdesivir for severe COVID-19, rates of clinical improvement were 96% and 89%, respectively, at day 28
    keywords: covid-19; day; days; patients; placebo; remdesivir; sars; treatment; use
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        item: #7739 of 7819
          id: cord-355365-goi0uw32
      author: Minocha, Amal
       title: Survey of ophthalmology practitioners in A&E on current COVID-19 guidance at three Major UK Eye Hospitals
        date: 2020-04-07
       words: 666
      flesch: 37
     summary: Our survey demonstrates a lack of confidence in and understanding of COVID-19 PHE guidance amongst ophthalmic practitioners, together with significant anxiety regarding exposure risk in the ophthalmic setting. We conducted a self-administered anonymous survey (Google Forms) disseminated by email of ophthalmology doctors, nurses, optometrists and healthcare assistants employed at Moorfields Eye Hospital, Western Eye Hospital and Manchester Royal Eye Hospital from 10 March 2020 to 12 March 2020 to assess perception of COVID-19 exposure risk, understanding and confidence in current Public Health England (PHE) guidelines for identifying possible COVID-19 cases, knowledge of Personal Protective Equipment (PPE) recommendations and training in its usage when managing such cases.
    keywords: covid-19; eye; practitioners
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        item: #7740 of 7819
          id: cord-355383-cqd2pa8c
      author: Olagoke, Ayokunle A.
       title: Exposure to coronavirus news on mainstream media: The role of risk perceptions and depression
        date: 2020-05-16
       words: 2848
      flesch: 38
     summary: Exposure to COVID-19 news on mainstream media was measured by asking participants four questions starting with the stem statement How frequently do you get information on coronavirus from any of the following sources? To further investigate the relationship between exposure to COVID-19 news on mainstream media and depressive symptoms, multivariable analysis was calculated to test the relationship between the exposure and depressive symptoms.
    keywords: covid-19; exposure; health; mainstream; media; news; symptoms
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        item: #7741 of 7819
          id: cord-355395-rckzi8vz
      author: Tian, Dandan
       title: Hepatic complications of COVID‐19 and its treatment
        date: 2020-05-21
       words: 2899
      flesch: 28
     summary: Liver injury may be a risk factor for progresses and worsens in patients with COVID‐19, and it is necessary to pay attention to the occurrence of liver injury in the diagnosis and treatment of COVID‐19. With acute liver injury, clinicians should analyze and judge the causes of liver injury and take appropriate measures, while closely monitoring ALT, AST, total bilirubin, direct bilirubin, albumin, and PTA (INR).
    keywords: coronavirus; covid-19; disease; injury; liver; patients; sars
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        item: #7742 of 7819
          id: cord-355431-efwuy8p9
      author: Ambrosio, Luca
       title: The role of the orthopaedic surgeon in the COVID-19 era: cautions and perspectives
        date: 2020-05-27
       words: 4993
      flesch: 35
     summary: Hospitals have been restructured to provide the best care to COVID-19 patients while adopting preventive strategies not to spread the infection among healthcare providers and patients affected by other diseases. In all other situations, wearing a surgical mask is reasonably safe when providing direct care to COVID-19 patients, especially in case of respirator scarcity [51, 58] .
    keywords: care; cases; coronavirus; covid-19; health; healthcare; orthopaedic; pandemic; patients; ppe; risk; surgery; use
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        item: #7743 of 7819
          id: cord-355441-0b266hwn
      author: Misztal, Krzysztof
       title: The importance of standardisation – COVID-19 CT&Radiograph Image Data Stock for deep learning purpose
        date: 2020-10-28
       words: 3095
      flesch: 47
     summary: Chest CT findings of COVID-19 pneumonia by duration of symptoms Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR Chest CT for typical 470 2019-nCoV pneumonia: relationship to negative RT-PCR testing Imaging changes of severe COVID-19 pneumonia in advanced stage Breaking the Testing Logjam: CT scan diagnosis ACR Recommendations for the use of Chest Radiography and Computed Tomography (CT) for Suspected COVID-19 Infection acr.org/Advocacy-and-Economics/ACR-Position-Statements/ Recommendations-for-Chest-Radiography-and-CT-for-Suspected-COVID19-Infection Sample-Efficient Deep Learning for COVID-19 Diagnosis Based on CT Scans Automated detection of COVID-19 cases using deep neural networks with X-ray images As of 15 July 2020, a total of 13,690,108 confirmed cases with COVID-19 pneumonia have been reported globally, including 586,265 deaths (4.28 %).
    keywords: covid-19; data; dataset; image; pneumonia; radiograph
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        item: #7744 of 7819
          id: cord-355447-0xuzolt3
      author: Miller, D. J.
       title: Leveraging wearable technology to predict the risk of COVID-19 infection.
        date: 2020-06-19
       words: 3744
      flesch: 41
     summary: Respiratory rate, RHR, and HRV were extracted between 01 November 2019 and 30 November 2019; respiratory rate was additionally sampled between 1 January 2020 and 06 June 2020 for individuals that reported test results for COVID-19. . If deviations in respiratory rate are found to be an accurate indicator of COVID-19 infection, respiratory rate monitoring could form part of the protocol used by medical professionals and organizations to enforce self-isolation and target testing.
    keywords: covid-19; days; license; medrxiv; preprint; rate
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        item: #7745 of 7819
          id: cord-355475-kdubhh73
      author: Patton, Lauren L.
       title: Viral Pandemics and Oral Health: Lessons Learned From HIV to SARS-CoV-2
        date: 2020-11-05
       words: 2162
      flesch: 36
     summary: Oral Surg Oral Med Oral Pathol Oral Radiol DOI: 10.1016/j.oooo.2020.10.022 sha: doc_id: 355475 cord_uid: kdubhh73 nan training was from James J. Crawford, PhD and I was memorably impacted by his What if Saliva Were Red video. The real hope is for saliva-based point-of-care rapid tests, as was created in OraQuick Advance® HIV-1/2 (Orasure Technologies, Inc.) for diagnosis of HIV infection.
    keywords: covid-19; disease; health; hiv; infection; patients; saliva; sars
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        item: #7746 of 7819
          id: cord-355484-2igc5wzx
      author: Oteo, J. A.
       title: A short therapeutic regimen based on hydroxychloroquine plus azithromycin for the treatment of COVID-19 in patients with non-severe disease. A strategy associated with a reduction in hospital admissions and complications.
        date: 2020-06-12
       words: 3377
      flesch: 54
     summary: At the time of writing this paper no medical therapy is officially recommended or has shown results in improving the outcomes in COVID-19 patients. At the time of writing this paper no medical therapy is officially recommended or has shown results in improving the outcomes in COVID-19 patients (5).
    keywords: days; hospital; license; patients; preprint
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        item: #7747 of 7819
          id: cord-355503-9baof9z8
      author: Yan, Aihua
       title: How hospitals in mainland China responded to the outbreak of COVID-19 using IT-enabled services: an analysis of hospital news webpages
        date: 2020-04-20
       words: 3831
      flesch: 43
     summary: At the early stage of the study, hospitals focused more on publishing popular medical science articles on their websites (T1) and also digitalized hospital processes (T2), but in latter stages of the study they focused more on knowledge management for medical professionals (T3) and telemedicine (T4). Third, digitalization of hospital processes is a trend.
    keywords: china; covid-19; healthcare; hospitals; patients; services; study; themes; training
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        item: #7748 of 7819
          id: cord-355528-y4a1g6km
      author: Balla, Mamtha
       title: COVID-19, Modern Pandemic: A Systematic Review From Front-Line Health Care Providers’ Perspective
        date: 2020-03-30
       words: 7523
      flesch: 53
     summary: Patients can catch it by breathing in droplets if they are standing within 1 m of COVID-19 patients. Drills and emergency preparedness about COVID-19 should be performed in all health care facilities involving providers who will be in touch with COVID-19 suspected patients.
    keywords: cases; china; coronavirus; covid-19; disease; et al; health; infection; novel; patients; pneumonia; sars; treatment
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        item: #7749 of 7819
          id: cord-355533-5kgdg2nb
      author: Kline, Jonathan D
       title: Sentinel Case of COVID-19 at Fort Stewart, GA in a National Guard Soldier Participating in Annual Training: A Case Report
        date: 2020-06-22
       words: 2151
      flesch: 39
     summary: This facility does not boast a true intensive care unit (ICU) capability, but a dedicated wing of the intermediate care ward was quickly outfitted, staffed, and isolated for the sole purpose of longterm management of COVID-19 patients in the event that transfer to an off-installation ICU was denied because of civilian hospitals reaching capacity. Interim guidelines for the clinical management of COVID-19 positive patients are available online and frequently updated.
    keywords: coronavirus; covid-19; health; infection; patient; symptoms
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        item: #7750 of 7819
          id: cord-355537-pckjq1n2
      author: Hatef, Elham
       title: Assessing the Impact of Neighborhood Socioeconomic Characteristics on COVID-19 Prevalence Across Seven States in the United States
        date: 2020-09-22
       words: 2693
      flesch: 41
     summary: We assessed the impact of neighborhood socioeconomic characteristics on COVID-19 prevalence in selected states; Arizona (AZ), Florida (FL), Illinois (IL), Maryland (MD), North Carolina (NC), South Carolina (SC), and Virginia (VA). We used data on the number of cumulative confirmed COVID-19 cases at the zip-code level and percentage of the population tested for COVID-19 in the seven states on two selected dates, May 3rd, 2020 (when COVID-19 prevalence had an upward trend across the country) and May 30th, 2020 (when COVID-19 prevalence presented a downward trend in selected areas)
    keywords: adi; covid-19; data; prevalence; states
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        item: #7751 of 7819
          id: cord-355540-rlvzj2e5
      author: Bodei, Lisa
       title: Peptide Receptor Radionuclide Therapy During the COVID-19 Pandemic: Are There Any Concerns?
        date: 2020-08-17
       words: 1576
      flesch: 31
     summary: We do, however, recommend careful vigilance regarding the incidence and clinical course of COVID-19 cases in patients undergoing PRRT, and we recommend postponing treatment in active COVID-19 infection. Subclinical kidney injury is thought to occur in many COVID-19 patients, severely in about 3% of older subjects with hypertension (19) .
    keywords: aaa; covid-19; patients; prrt; risk
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        item: #7752 of 7819
          id: cord-355549-6xnjj5h5
      author: Cécile, Couchoud
       title: Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients.
        date: 2020-08-25
       words: 4018
      flesch: 44
     summary: key: cord-355549-6xnjj5h5 authors: Cécile, Couchoud; Florian, Bayer; Carole, Ayav; Clémence, Béchade; Philippe, Brunet; François, Chantrel; Luc, Frimat; Roula, Galland; Maryvonne, Hourmant; Emmanuelle, Laurain; Thierry, Lobbedez; Lucile, Mercadal; Olivier, Moranne title: Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients. 6xnjj5h5 The aim of this study was to estimate the incidence of COVID-19 disease in the French national population of dialysis patients, their course of illness and to identify the risk factors associated with mortality.
    keywords: care; covid-19; dialysis; disease; france; mortality; patients; population; risk
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        item: #7753 of 7819
          id: cord-355558-r6r1t47c
      author: Shenoy, Akhil
       title: Diabetes and covid-19: a global health challenge
        date: 2020-04-27
       words: 1435
      flesch: 46
     summary: It may also be cautioned that severe covid-19 patients with diabetes were older in age and had associated comorbidities including hypertension, cardiovascular disease and cerebrovascular disease than the non-diabetic patients (although even after adjustment for these comorbidities, patients with diabetes had a lower survival rate than nondiabetics). Taken together, diabetes may be associated with a higher risk of severe covid-19 disease and a necessity for mechanical ventilation as well as risk of death.
    keywords: covid-19; diabetes; disease; patients
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        item: #7754 of 7819
          id: cord-355567-60sfv60p
      author: Azuma, Kenichi
       title: Environmental factors involved in SARS-CoV-2 transmission: effect and role of indoor environmental quality in the strategy for COVID-19 infection control
        date: 2020-11-03
       words: 9233
      flesch: 37
     summary: World Health Organization Saliva: potential diagnostic value and transmission of 2019-nCoV Measures against COVID-19 concerning Summer Indoor Environment in Japan Interaction of aerosol particles composed of protein and salts with water vapor: hygroscopic growth and microstructural rearrangement Study on thermal environmental ununiformity in office buildings Survey on control of indoor air environment in office buildings: Part5 evaluation of thermal environment by domestic and international standards Wells revisited: infectious particles vs. quanta of mycobacterium tuberculosis infection-don't get them confused Risk of indoor airborne infection transmission estimated from carbon dioxide concentration A probabilistic transmission dynamic model to assess indoor airborne infection risks Potential for airborne transmission of infection in the waiting areas of healthcare premises: stochastic analysis using a Monte Carlo model Review and comparison between the Wells-Riley and dose response approaches to risk assessment of infectious respiratory diseases Airborne infection. Theoretical limits of protection achievable by building ventilation The detection of airborne transmission of tuberculosis from HIV-infected patients, using an in vivo air sampling model A probabilistic transmission model to assess infection risk from mycobacterium tuberculosis in commercial passenger trains Spatial distribution of infection risk of SARS transmission in a hospital ward Airborne spread of measles in a suburban elementary school Cleaning the air: the theory and application of ultraviolet air disinfection HVAC filtration and the Wells-Riley approach to assessing risks of infectious airborne diseases Association of infected probability of COVID-19 with ventilation rates in confined spaces: a Wells-Riley equation based investigation Characterization of expiration air jets and droplet size distributions immediately at the mouth opening Size distribution and sites of origin of droplets expelled from the human respiratory tract during expiratory activities Airborne spread of expiratory droplet nuclei between the occupants of indoor environments: A review ASHRAE position document on airborne infectious diseases HVAC filtration for controlling infectious airborne disease transmission in indoor environments: predicting risk reductions and operational costs The history of ultraviolet germicidal irradiation for air disinfection Guidelines for environmental infection control in health-care facilities ASHRAE.
    keywords: air; control; coronavirus; cov-2; covid-19; droplets; environmental; infection; particles; rate; sars; spaces; surfaces; transmission; ventilation; virus
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        item: #7755 of 7819
          id: cord-355577-w1yhtbz8
      author: Kowalski, Luiz Paulo
       title: Effect of the COVID-19 Pandemic on the Activity of Physicians Working in the Areas of Head and Neck Surgery and Otorhinolaryngology
        date: 2020-05-22
       words: 4751
      flesch: 46
     summary: An unexpected finding in our study was the low amount of surgeries (22 cases) performed in COVID-19 patients, given the presence of more than 500 surgeons among responders, most of them with more than 10 years of experience in the field. 27 Elective tracheostomies in COVID-19 patients have a narrower range of indication, due to the increased risk of aerosolization and contagion.
    keywords: care; covid-19; head; neck; oncologists; pandemic; patients; physicians; reduction; risk
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        item: #7756 of 7819
          id: cord-355578-z4rjwknv
      author: Stoker, Steven
       title: Effect of Shelter-in-Place Orders and the COVID-19 Pandemic on Orthopaedic Trauma at a Community Level II Trauma Center
        date: 2020-06-08
       words: 3293
      flesch: 52
     summary: Year-over-year analysis was performed on high severity trauma with fracture and/or dislocation (HWF), low severity trauma with fracture or dislocation (LWF), low severity trauma without fracture or dislocation (LOF), and a combined low severity using a 1-tailed Student t test (Table 1) . Although there are several validated trauma severity classifications, a literature review did not return any validated classifications focused specifically on orthopaedic trauma severity; therefore, the algorithm was created (Fig. 1) .
    keywords: covid-19; march; order; otes; place; severity; shelter
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        item: #7757 of 7819
          id: cord-355589-3zdv9zim
      author: Simons, David
       title: The association of smoking status with SARS‐CoV‐2 infection, hospitalisation and mortality from COVID‐19: A living rapid evidence review with Bayesian meta‐analyses (version 7)
        date: 2020-10-02
       words: 5238
      flesch: 31
     summary: A Hospital Staff Data Clinical characteristics of 36 non-survivors with COVID-19 in Wuhan Acute Myocardial Injury of Patients with Coronavirus Disease Epidemiological and Clinical Characteristics of 17 Hospitalized Patients with 2019 Novel Coronavirus Infections Outside Wuhan Risk Factors Associated with Clinical Outcomes in 323 COVID-19 Patients in Wuhan Epidemiological and clinical features of 125 Hospitalized Patients with COVID-19 in Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 2019 -United States Eleven faces of coronavirus disease 2019 Clinical Course and Outcomes of Patients with Severe Acute Respiratory Syndrome Coronavirus 2 Infection: a Preliminary Report of the First 28 Patients from the Korean Cohort Study on COVID-19 Host susceptibility to severe COVID-19 and establishment of a host risk score: findings of 487 cases outside Wuhan Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series COVID-19 Fatality and Comorbidity Risk Factors among Confirmed Patients in Mexico Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area Cluster of COVID-19 in northern France: A retrospective closed cohort study Letter to the Editor: Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease Clinical Characteristics and Risk factors for developed COVID-19 patients transferring to designated hospital from Jianghan Fangcang shelter Hospital: a retrospective, observational study Clinical features of coronavirus disease 2019 (COVID-19) in a cohort of patients with disability due to spinal cord injury Clinical characteristics of imported and second-generation COVID-19 cases outside Wuhan, China: A multicenter retrospective study Impaired type I interferon activity and exacerbated inflammatory responses in severe Covid-19 patients Characteristics and Clinical Outcomes of Adult Patients Hospitalized with COVID-19 -Georgia Association Between Clinical Manifestations and Prognosis in Patients with COVID-19 Epidemiological and clinical characteristics analysis of COVID-19 in the surrounding areas of Wuhan, Hubei Province in 2020 Low albumin levels are associated with poorer outcomes in a case series of COVID-19 patients in Spain: a retrospective cohort study Clinical characteristics of 106 patients with neurological diseases and co-morbid coronavirus disease 2019: a retrospective study Neutrophil calprotectin identifies severe pulmonary disease in COVID-19 Smoking and the risk of COVID-19 infection in the UK Biobank Prospective Study Multivariable prediction model of intensive care unit transfer and death: a French prospective cohort study of COVID-19 patients Determinants of Severity in Cancer Patients with COVID-19 Illness OpenSAFELY: factors associated with COVID-19 death in 17 million patients A Cohort of Patients with COVID-19 in a Major Teaching Hospital in Europe 30-day mortality in patients hospitalized with COVID-19 during the first wave of the Italian epidemic: A prospective cohort study Clinical features, diagnostics, and outcomes of patients presenting with acute respiratory illness: a comparison of patients with and without COVID-19 Clinical and Genetic Characteristics of Covid-19 Patients from UK Biobank Is sleep apnoea a risk factor for Covid-19? First report from Saudi Arabia Risk of infection and hospitalization by Covid-19 in Mexico: a case-control study Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry Olfactory Dysfunction in Recovered Coronavirus Disease 2019 (COVID-19) Patients Psychosocial factors and hospitalisations for COVID-19: Prospective cohort study of the general population Clinical predictors of donor antibody titer and correlation with recipient antibody response in a COVID-19 convalescent plasma clinical trial Chronic ACE Inhibitor use is Associated with Decreased Odds of Severe Disease in Patients with COVID-19 Intraluminal Carotid Artery Thrombus in COVID-19: Another Danger of Cytokine Storm? Impact of SARS-CoV-2 Viral Load on Risk of Intubation and Mortality Among Hospitalized Patients with Coronavirus Disease IL6 inhibition in critically ill COVID-19 patients is associated with increased secondary infections Profiling pre-symptomatic and asymptomatic cases with confirmed SARS-CoV-2 infection in Mexico City Association of SARS-CoV-2 Genomic Load with COVID-19 Patient Outcomes Health-care workers with COVID-19 living in Mexico City: clinical characterization and related outcomes ROX Index Predicts Intubation in Patients with COVID-19 Pneumonia and Moderate to Severe Hypoxemic Respiratory Failure Receiving High Flow Nasal Therapy Low plasma 25(OH) vitamin D3 level is associated with increased risk of COVID-19 infection: an Israeli population-based study Pre-diagnostic circulating concentrations of insulin-like growth factor-1 and risk of COVID-19 mortality: results from UK Biobank Association of Cancer with Risk and Mortality of COVID-19: Results from the UK Biobank Natural killer cell activation related to clinical outcome of COVID-19 Digestive Manifestations in Patients Hospitalized with COVID-19 Risk Factors Prediction, Clinical Outcomes, and Mortality of COVID-19 Patients Early Diagnosis and Clinical Significance of Acute Cardiac Injury -Under the Iceberg: A Retrospective Cohort Study of 619 Non-critically Ill Hospitalized COVID-19 Pneumonia Patients Clinical outcomes and risk factors for severe COVID-19 infection in patients with haematological disorders receiving chemo-or immunotherapy Initial experience in Mexico with convalescent plasma in COVID-19 patients with severe respiratory failure, a retrospective case series Observational Study of Haloperidol in Hospitalized Patients with Covid-19 COVID-19 Case Series at UnityPoint Health St. Lukes Hospital in Cedar Rapids Broncho-alveolar inflammation in COVID-19 patients: a correlation with clinical outcome IgG antibody seroconversion and the clinical progression of COVID-19 pneumonia:
    keywords: clinical; covid-19; disease; patients; risk; smokers; smoking; status; studies; study
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        item: #7758 of 7819
          id: cord-355590-io3qv72x
      author: Kanburoglu, Mehmet Kenan
       title: The Challenges of Contact Tracing in a Case of Early Neonatal Sepsis with COVID-19
        date: 2020-06-22
       words: 498
      flesch: 48
     summary: To find the source of transmission, we investigated all the people who may have had contact with the baby, including the family members and the hospital staff, by testing with nasopharyngeal COVID-19 PCR and for total IgG and IgM (Hotgen Biotech Co.). Characteristics and assessment of the usefulness of serological tests in the diagnostic of infections caused by coronavirus SARS-CoV-2 on the basis of available manufacturer's data and literature review Antibody responses to SARS-CoV-2 in patients of novel coronavirus disease 2019 SARS-CoV-2 infection in children Epidemiological characteristics of 2143 pediatric patients with 2019 coronavirus disease in China Clinical and CT features in pediatric patients with COVID-19 infection: different points from adults Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Conflict of Interest None.
    keywords: contact; covid-19
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        item: #7759 of 7819
          id: cord-355593-91bho7aw
      author: A Mohsen, Ahmed
       title: Global stability of COVID-19 model involving the quarantine strategy and media coverage effects
        date: 2020-08-03
       words: 3427
      flesch: 57
     summary: key: cord-355593-91bho7aw authors: A Mohsen, Ahmed; AL-Husseiny, Hassan Fadhil; Zhou, Xueyong; Hattaf, Khalid title: Global stability of COVID-19 model involving the quarantine strategy and media coverage effects date: 2020-08-03 journal: AIMS Public Health DOI: 10.3934/publichealth.2020047 sha: doc_id: 355593 cord_uid: 91bho7aw In this paper, we build and analyze a mathematical model of COVID-19 transmission considering media coverage effects. Furthermore, to shown and understand the effect of quarantine rate of disease we have choosed many different value of it say parameter then we have obtained some different results see Table 4 and Figure 4 . Coronavirus disease (COVID-2019) Situation reports SEIR transmission dynamics model of 2019 nCov coronavirus with considering the weak infectious ability and changes in latency duration Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia Pattern of early human to human transmission of Wuhan Feasibility of controlling 2019-nCoV outbreaks by isolation of cases and contacts A mathematical model for simulation the phase-based transmissibility of novel coronavirus Parameter estimation and prediction for corona virus disease outbreak 2019 (COVID-19) in Algeria Analysis of a Model for Corona virus spread A nonlinear epidemiological model considering asymptotic and quarantine classes for SARS CoV-2 virus Estimating the effects of non-pharmaceutical interventions on COVID-19 in Europe Modeling the effects of intervention strategies on COVID-19 transmission dynamics Modelling the effects of media coverage and quarantine on the COVID-19 infections in the UK Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission
    keywords: covid-19; equilibrium; model
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        item: #7760 of 7819
          id: cord-355603-j811a48x
      author: Lee, KarlaA.
       title: Cancer and Risk of COVID‐19 Through a General Community Survey
        date: 2020-08-26
       words: 1484
      flesch: 42
     summary: Rapid implementation of mobile technology for realtime epidemiology of COVID-19 Realtime tracking of self-reported symptoms to predict potential COVID-19 Patients with cancer appear more vulnerable to SARS-CoV-2: A multicenter study during the COVID-19 outbreak Cancer patients in SARS-CoV-2 infection: A nationwide analysis in China Do patients with cancer have a poorer prognosis of COVID-19? key: cord-355603-j811a48x authors: Lee, KarlaA.; Ma, Wenjie; Sikavi, Daniel R.; Drew, David A.; Nguyen, Long H.; Bowyer, Ruth; Cardoso, M. Jorge; Fall, Tove; Freidin, Maxim B.; Gomez, Maria; Graham, Mark; Guo, Chuan‐Guo; Joshi, Amit D.; Kwon, Sohee; Lo, Chun‐Han; Lochlainn, Mary Ni; Menni, Cristina; Murray, Benjamin; Mehta, Raaj; Song, Mingyang; Sudre, Carole H.; Bataille, Veronique; Varsavsky, Thomas; Visconti, Alessia; Franks, Paul W.; Wolf, Jonathan; Steves, Claire J.; Ourselin, Sebastien; Spector, Tim D.; Chan, Andrew T. title: Cancer and Risk of COVID‐19 Through a General Community Survey date: 2020-08-26 journal: Oncologist DOI: 10.1634/theoncologist.2020-0572 sha: doc_id: 355603 cord_uid: j811a48x Individuals with cancer may be at high risk for coronavirus disease 2019 (COVID‐19) and adverse outcomes.
    keywords: cancer; covid-19; individuals; patients; risk
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        item: #7761 of 7819
          id: cord-355650-1x66nxgx
      author: Kumar, S.
       title: Will COVID-19 pandemic diminish by summer-monsoon in India? Lesson from the first lockdown
        date: 2020-04-25
       words: 6952
      flesch: 52
     summary: We found a negative association of humidity (RH and AH) with daily COVID-19 Cases (Persons r=-0.62, -0.37). We found a negative association of humidity (RH and AH) with daily COVID-19 Cases (Person's r=-0.62, -0.37).
    keywords: april; cases; covid-19; humidity; india; license; lockdown; preprint; temperature
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        item: #7762 of 7819
          id: cord-355669-90rauz66
      author: Strausz, S.
       title: Sleep apnoea is a risk factor for severe COVID-19
        date: 2020-09-28
       words: 2101
      flesch: 45
     summary: We did not observe differences in risk factors when comparing non-hospitalized (N=10, male 50%, mean age 57.8) and hospitalized OSA patients (N=16, male 43.8%, mean age 66.2 years), (Table 2) . To examine whether the risk for contracting COVID-19 is elevated among OSA patients.
    keywords: covid-19; osa; patients; preprint; risk
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        item: #7763 of 7819
          id: cord-355674-mhi85px5
      author: Siddiqi, Hasan K.
       title: Increased prevalence of myocardial injury in patients with SARS-CoV-2 viremia.
        date: 2020-11-10
       words: 1736
      flesch: 40
     summary: CONCLUSIONS: Hospitalized COVID-19 patients with SARS-CoV-2 viremia have a significantly higher prevalence of detectable troponin and myocardial injury during their hospitalization, compared to non-viremic patients. Conclusions: Hospitalized COVID-19 patients with SARS-CoV-2 viremia have a significantly higher prevalence of detectable troponin and myocardial injury during their hospitalization, compared to non-viremic patients.
    keywords: cov-2; patients; sars; viremia
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        item: #7764 of 7819
          id: cord-355700-1yf1ae1d
      author: Chen, Y.
       title: How Efficient Can Non-Professional MasksSuppress COVID-19 Pandemic?
        date: 2020-06-03
       words: 3732
      flesch: 53
     summary: With face mask k, the effective transmission rate β k can be formulated as where the amount of viruses per contact is reduced by factor γ 2 k , if both susceptible and infected individuals use face masks. For instance, for face mask k, we can compute the sum area of the surfaces of the total penetrated aerosols as where N k stands for the number of penetrate aerosols out of all N attacking aerosols, and d
    keywords: covid-19; face; face masks; masks; number; pandemic
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        item: #7765 of 7819
          id: cord-355713-zupocnuf
      author: Li, Junxiong
       title: Changing Grocery Shopping Behaviours Among Chinese Consumers At The Outset Of The COVID‐19 Outbreak
        date: 2020-06-12
       words: 4059
      flesch: 43
     summary: For this purpose, the theory of planned behaviour first posited by Ajzen (1991) is adopted to explore planned changes to consumer food shopping behaviours at the early stages of the COVID-19 outbreak in China. In contrast, there was a surge in online shopping, with the percentage of consumers buying food and groceries online increasing from 11 per cent before the outbreak to 38 per cent, with online food shopping becoming the most popular channel during the outbreak.
    keywords: behaviour; cent; china; covid-19; food; online; outbreak; retail; shopping; study
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        item: #7766 of 7819
          id: cord-355734-pz64534w
      author: Antonio-Villa, Neftali Eduardo
       title: Health-care workers with COVID-19 living in Mexico City: clinical characterization and related outcomes
        date: 2020-09-28
       words: 3267
      flesch: 38
     summary: First, we analyzed a large dataset which included information on confirmed positive and negative SARS-CoV-2 cases in Mexico City, providing a unique opportunity to investigate COVID-19 specific risk factors in HCWs. In this work, we report the prevalence of SARS-CoV-2 infection, related symptomatology, and COVID-19 clinical outcomes using a city-wide based surveillance reports of HCWs living in Mexico City.
    keywords: cases; cov-2; covid-19; hcws; outcomes; risk; sars
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        item: #7767 of 7819
          id: cord-355753-muefay2n
      author: Garner, Justin L.
       title: Challenges of evaluating lung function as part of cancer care during the COVID-19 pandemic
        date: 2020-07-02
       words: 1264
      flesch: 22
     summary: Total lung capacity and residual volumes, estimated on CT scans respectively made in maximum inspiration and expiration have also been shown to correlate well with plethysmographic-derived measurements (17) . The Lancet Oncology Guidelines on the radical management of patients with lung cancer Pulmonary Function Laboratories: Advice Regarding COVID-19 Peak-flow or portable spirometry as a replacement for Spirometry in the diagnosis of COPD and Asthma The Use of Home Spirometry in Pediatric Cystic Fibrosis Patients: Results of a Feasibility Study Development of quantitative computed tomography lung protocols Relationships between airflow obstruction and quantitative CT measurements of emphysema, air trapping, and airways in subjects with and without chronic obstructive pulmonary disease Prediction of postoperative lung function in patients with lung cancer: comparison of quantitative CT with perfusion scintigraphy A randomized study using functional respiratory imaging to characterize bronchodilator effects of glycopyrrolate/formoterol fumarate delivered by a metered dose inhaler using cosuspension delivery technology in patients with COPD Quantitative Evaluation of Lobar Pulmonary Function of Emphysema Patients with Endobronchial Coils.
    keywords: cancer; covid-19; lung; patients
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        item: #7768 of 7819
          id: cord-355755-fd40zy7z
      author: Alsadhan, Ibrahim
       title: Diabetic Ketoacidosis Precipitated by COVID-19 infection: Case Series
        date: 2020-10-27
       words: 3499
      flesch: 53
     summary: However, we are unaware of any reported cases of DKA among COVID-19 patients in Saudi Arabia. (9) Contrary to this finding, another study found that COVID-19 patients with diabetes who developed DKA were more likely to survive compared to patients without DKA.
    keywords: covid-19; diabetes; dka; insulin; mmol; patient; range
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        item: #7769 of 7819
          id: cord-355772-kvenaqj3
      author: Wang, Xuan
       title: Letter: Strategies for Prevention and Control of 2019 Novel Coronavirus Infection Among Medical Staff
        date: 2020-04-11
       words: 2303
      flesch: 47
     summary: Here, we would like to summarize and share our successful experiences in the prevention and control of SARS-CoV-2 infection in medical staff of hospital departments, especially those devoted to non-infection diseases. With the awareness of the high rate of infection in the medical staff, combined with the statistical results, we drew up strategies for emergency management and daily protection for medical staff in departments of non-infection disease during this severe epidemic.
    keywords: covid-19; department; infection; patients; staff; treatment
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        item: #7770 of 7819
          id: cord-355773-k9hut687
      author: Guerini, Andrea Emanuele
       title: Differential diagnosis and clinical management of a case of COVID-19 in a stage III lung cancer patient treated with radio-chemotherapy and durvalumab.
        date: 2020-06-02
       words: 2357
      flesch: 36
     summary: This phenomenon could explain the higher levels of cytokines including IL-6 and TNF measured in patients developing severe respiratory symptoms [17] and the investigation of immunosuppressants such as chloroquine and tocilizumab (a humanized monoclonal antibody targeting IL-6 receptor, also used to manage steroid-refractory pneumonitis induced by PD-L1 inhibitors) for Covid-19 treatment [18, 19] . This report outlines the complexity and the importance of early detection of COVID-19, even more in NSCLC patients, who are already at higher risk of developing severe pneumonitis on a multifactorial basis.
    keywords: clinical; covid-19; lung; patients; pneumonitis; treatment
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        item: #7771 of 7819
          id: cord-355776-f8u66hbt
      author: Ni, Zhao
       title: Response to the COVID-19 Outbreak in Urban Settings in China
        date: 2020-09-09
       words: 4357
      flesch: 44
     summary: In this paper, the time point of COVID-19 outbreak refers to January 23 rd , 2020, when Wuhan city was placed in quarantine. Available at Hangzhou makes public spitting illegal The People's Government of Shanxi Province Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 outbreak in China: a web-based cross-sectional survey Increased generalized anxiety, depression and distress during the COVID-19 pandemic: a cross-sectional study in Germany A Nationwide Survey of Psychological Distress among Italian People during the COVID-19 Pandemic: Immediate Psychological Responses and Associated Factors
    keywords: anxiety; china; covid-19; depression; health; outbreak; pandemic; participants; survey; symptoms
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        item: #7772 of 7819
          id: cord-355777-zly3ddtr
      author: Lieberman-Cribbin, Wil
       title: Disparities in COVID-19 Testing and Positivity in New York City
        date: 2020-06-25
       words: 2392
      flesch: 48
     summary: The objectives of this analysis are: (1) to study the spatial distribution of the number of COVID-19 tests, of COVID-19 positive tests, and the ratio of positive to total tests according to ZIP Code Tabulation Area (ZCTA); (2) determine factors associated with testing and with positive testing according to ZCTA. An ecological study was performed to determine the spatial distribution of COVID-19 testing by ZIP Code Tabulation Area and investigate if testing was associated with race or SES.
    keywords: covid-19; data; index; ses; testing; tests
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        item: #7773 of 7819
          id: cord-355824-7p7lov2e
      author: Ladds, E.
       title: Persistent symptoms after Covid-19: qualitative study of 114 long Covid patients and draft quality criteria for services
        date: 2020-10-14
       words: 6658
      flesch: 51
     summary: key: cord-355824-7p7lov2e authors: Ladds, E.; Rushforth, A.; Wieringa, S.; Taylor, S.; Rayner, C.; Husain, L.; Greenhalgh, T. title: Persistent symptoms after Covid-19: qualitative study of 114 long Covid patients and draft quality criteria for services date: 2020-10-14 journal: nan DOI: 10.1101/2020.10.13.20211854 sha: doc_id: 355824 cord_uid: 7p7lov2e Background Approximately 10% of patients with Covid-19 experience symptoms beyond 3-4 weeks. 11 12 The high proportion of women in long Covid support groups 4 12 may or may not reflect a true gender difference in incidence.
    keywords: covid-19; illness; license; medrxiv; medrxiv preprint; participants; perpetuity; preprint; services; symptoms
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        item: #7774 of 7819
          id: cord-355830-kctpftm9
      author: Perisetti, Abhilash
       title: Putative Mechanisms of diarrhea in COVID-19
        date: 2020-06-12
       words: 636
      flesch: 50
     summary: However, fecal calprotectin is elevated in COVID-19 patients with persistent diarrhea, which is consistent with increased gut inflammation. First, we would like to stress the importance of having a strict definition of diarrhea in COVID-19 patients, mainly because diarrhea can develop with any kind of viral illness and it is usually short-lived (<48 hours).
    keywords: covid-19; diarrhea
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        item: #7775 of 7819
          id: cord-355847-1ru15s5a
      author: Convertino, Irma
       title: Exploring pharmacological approaches for managing cytokine storm associated with pneumonia and acute respiratory distress syndrome in COVID-19 patients
        date: 2020-06-11
       words: 2944
      flesch: 35
     summary: Several drugs, endowed with modulating activity on cytokine pathways, including anti-IL-6, anti-TNF, and Janus kinase (JAK) inhibitors, currently approved for the treatment of immune-mediated inflammatory diseases, have been suggested or could be yet taken into account for experimental use in COVID-19 patients with ARDS and/or pneumonia ( Fig. 1 ). Moreover, a multicenter randomized clinical trial in COVID-19 patients with ARDS, treated with tocilizumab at a dose of 4~8 mg/kg once, and an additional same dose when fever persists within 24 h after the first administration, has been approved in China [16] .
    keywords: anti; ards; covid-19; il-6; iqr; patients; tnf
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        item: #7776 of 7819
          id: cord-355850-jgcjscjq
      author: Elhadi, Muhammed
       title: Assessment of Healthcare Workers’ Levels of Preparedness and Awareness Regarding COVID-19 Infection in Low-Resource Settings
        date: 2020-06-18
       words: 3420
      flesch: 43
     summary: We focused on healthcare workers who may come into direct contact with COVID-19 patients, and are thus expected to have adequate knowledge and preparedness. 25, 26 The majority of healthcare workers (77.4%) felt personally unprepared to address COVID-19 infection.
    keywords: covid-19; doctors; healthcare; knowledge; nurses; preparedness; study; workers
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        item: #7777 of 7819
          id: cord-355854-hksq8gy4
      author: Pagliaro, Pasquale
       title: ACE/ACE2 Ratio: A Key Also in 2019 Coronavirus Disease (Covid-19)?
        date: 2020-06-18
       words: 3034
      flesch: 36
     summary: ACE2 expression could influence the course of Covid-19 in different ways: increased expression might promote viral entry, whereas ACE2 increased expression may be beneficial due to ACE2 antiinflammatory and other beneficial effects (Figure 1 ) that could prevent pulmonary edema, ARDS, hypoxia, and redox stress development. Implications to SARS-CoV-2-related cardiovascular complications Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target Study on the correlation among sex, age and the activity of ACE, ACE2 and the ratio of ACE/ACE2 High-salt diet increases glomerular ACE/ACE2 ratio leading to oxidative stress and kidney damage High glucose-induced Nox1-derived superoxides downregulate PKC-betaII, which subsequently decreases ACE2 expression and ANG(1-7) formation in rat VSMCs Activation of reninangiotensin-aldosterone system (RAAS) in the lung of smoking-induced pulmonary arterial hypertension (PAH) rats Expression of ACE and ACE2 in individuals with diabetic kidney disease and healthy controls Angiotensinconverting enzyme 2 is reduced in Alzheimer's disease in association with increasing amyloid-β and tau pathology Synergistic expression of angiotensin-converting enzyme (ACE) and ACE2 in human renal tissue and confounding effects of hypertension on the ACE to ACE2 ratio Relationship between renal injury and the antagonistic roles of angiotensin-converting enzyme (ACE) and ACE2 High-salt diets during pregnancy affected fetal and offspring renal renin-angiotensin system Enalapril protects against myocardial ischemia/reperfusion injury in a swine model of cardiac arrest and resuscitation Balance between angiotensin converting enzyme and angiotensin converting enzyme 2 in patients with chronic heart failure -7) prevented obesity and hepatic inflammation by inhibition of resistin/TLR4/MAPK/NF-κB in rats fed with high-fat diet Renin-angiotensin system may trigger kidney damage in NOD mice Effectiveness of convalescent plasma therapy in severe COVID-19 patients The his and hers of the renin-angiotensin system Viroporins and inflammasomes: a key to understand virus-induced inflammation Role of angiotensin II type 1 receptor on renal NAD(P)H oxidase, oxidative stress and inflammation in nitric oxide inhibition induced-hypertension Mousepassaged severe acute respiratory syndrome-associated coronavirus leads to lethal pulmonary edema and diffuse alveolar damage in adult but not young mice Pulmonary angiotensin-converting enzyme 2 (ACE2) and inflammatory lung disease SARS coronavirus spike proteininduced innate immune response occurs via activation of the NF-kappaB pathway in human monocyte macrophages in vitro Developmental origin of lung macrophage diversity COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches Cardiac macrophage biology in the steadystate heart, the aging heart, and following myocardial infarction SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS Hypoxic regulation of pulmonary vascular smooth muscle cyclic guanosine monophosphate-dependent kinase by the ubiquitin conjugating system Adaptation of iron requirement to hypoxic conditions at high altitude Hypocapnic alkalosis enhances oxidant-induced apoptosis of human alveolar epithelial type II cells Alkalosis in critically Ill patients with severe sepsis and septic shock Metabolic alkalosis is the most common acid-base disorder in ICU patients Oxidative stress markers to investigate the effects of hyperoxia in anesthesia Hyperoxia and oxidative stress in anesthesia and critical care medicine Oxygen in the critically ill: friend or foe?
    keywords: ace2; angiotensin; covid-19; enzyme; heart; patients; ratio; sars
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        item: #7778 of 7819
          id: cord-355892-9kkqmm6h
      author: Miller, Larry E.
       title: Diabetes mellitus increases the risk of hospital mortality in patients with Covid-19: Systematic review with meta-analysis
        date: 2020-10-02
       words: 3496
      flesch: 43
     summary: study mortality rate (%) 95% CI Funnel plot symmetry was evaluated for small-study effects, a one-study removed sensitivity analysis assessed the influence of individual studies on the pooled mortality rate, and metaregression assessed the association of potential confounding variables with mortality rates.
    keywords: analysis; china; covid-19; mortality; patients; rate; studies
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        item: #7779 of 7819
          id: cord-355897-9wqrl744
      author: Landi, Antonio
       title: The burden of thrombotic complications in critically ill patients with COVID-19: charting the uncharted
        date: 2020-06-05
       words: 748
      flesch: 28
     summary: Incidence of thrombotic complications in critically ill ICU patients with COVID-19 Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study Thrombotic complications of patients admitted to intensive care with COVID-19 at a teaching hospital in the United Kingdom Attention should be paid to venous thromboembolism prophylaxis in the management of COVID-19 Recently, several observational studies investigated the prevalence of thrombotic complications in COVID-19 patients admitted to ICU (Table 1) .
    keywords: complications; covid-19; patients
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        item: #7780 of 7819
          id: cord-355898-hlkwwaqe
      author: Grippo, Antonello
       title: Electroencephalography during SARS-CoV-2 outbreak: practical recommendations from the task force of the Italian Society of Neurophysiology (SINC), the Italian League Against Epilepsy (LICE), and the Italian Association of Neurophysiology Technologists (AITN)
        date: 2020-07-21
       words: 3950
      flesch: 29
     summary: The most representative scientific societies of health professionals involved in the EEG execution and reporting, Italian Society of Clinical Neurophysiology (SINC), Italian League Against Epilepsy (LICE), and the Italian Association of Neurophysiology Technologists (AITN), received several requests for indications on how to perform EEG examinations during this health emergency from their members. In addition, due to the reduction in the volume of EEG examinations, it should be considered that medical staff may be able to work on alternate days or rotating shifts to limit exposure to the infection, or may be moved to other areas depending on the needs of the hospital.
    keywords: covid-19; eeg; emergency; equipment; examination; italian; pandemic; patients; phase; procedures; recommendations
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        item: #7781 of 7819
          id: cord-355903-1yzebh7d
      author: Singh, Kumar Tathagat
       title: Preparedness among dental professionals towards COVID-19 in India
        date: 2020-06-19
       words: 2717
      flesch: 50
     summary: Shutting dental practices all through the pandemic can diminish the count of affected persons; however will amplify the distress of those in need of immediate dental care Table 2 shows differences in median total scores and interquartile range (IQR) among various demographic variables of respondents of KAP on dental practice during pandemic.
    keywords: dental; dentists; knowledge; pandemic; practice; scores
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        item: #7782 of 7819
          id: cord-355905-av03suua
      author: Romero Starke, Karla
       title: The Age-Related Risk of Severe Outcomes Due to COVID-19 Infection: A Rapid Review, Meta-Analysis, and Meta-Regression
        date: 2020-08-17
       words: 6828
      flesch: 55
     summary: The maximum number of risk factors used by the studies was five, which would result in a 1.4% increase in death per age year. The maximum number of important risk factors adjusted for by the studies was five, which resulted in a 3.5% increase in disease severity per age year.
    keywords: age; bias; covid-19; disease; risk; studies; study
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        item: #7783 of 7819
          id: cord-355910-nn4jxwym
      author: Kearon, Joanne
       title: The Role of Primary Care in a Pandemic: Reflections During the COVID-19 Pandemic in Canada
        date: 2020-09-27
       words: 2197
      flesch: 41
     summary: As Ontario prepares now for a potential second wave of COVID-19, primary care physicians have an opportunity to consider the full breadth and depth of scope for primary care during a pandemic. As part of these preparations, primary care physicians were ready to be redeployed to the hospitals.
    keywords: care; health; pandemic; physicians; primary
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        item: #7784 of 7819
          id: cord-355919-e8fhlo37
      author: Semaan, Aline
       title: Voices from the frontline: findings from a thematic analysis of a rapid online global survey of maternal and newborn health professionals facing the COVID-19 pandemic
        date: 2020-06-24
       words: 6758
      flesch: 40
     summary: Éditions L'Harmattan Patient and provider perspectives on how trust influences maternal vaccine acceptance among pregnant women in Kenya Trust in health care: theoretical perspectives and research needs Maladies et violences ordinaires dans un hôpital malgache Understanding social resistance to the Ebola response in the forest region of the Republic of guinea: an anthropological perspective Biology and culture are inseparable -considerations for the exit strategy expert group from the field of medical anthropology What is a resilient health system? The health impact of the 2014-15 Ebola outbreak Effects of the West Africa Ebola virus disease on health-care utilization -a systematic review Health-Care access during the Ebola virus epidemic in Liberia Women and babies are dying but not of Ebola': the effect of the Ebola virus epidemic on the availability, uptake and outcomes of maternal and newborn health services in Sierra Leone COVID-19 response in Uganda: notes and reflections Changes in health care utilization during the MERS epidemic COVID-19 technical brief for maternity services Women's Rights in Childbirth Must be Upheld During the Coronavirus Pandemic A chaotic week for pregnant women in New York City Reflections on COVID-19 Vaginal delivery in SARS-CoV-2-infected pregnant women in northern Italy: a retrospective analysis Coronavirus: baby blues as some mothers in France separated from newborn amid COVID-19 fears The scale, scope, coverage, and capability of childbirth care COVID-19 disrupts vaccine delivery World Health Organization.
    keywords: care; countries; covid-19; health; healthcare; income; lmics; maternity; mnh; pandemic; professionals; respondents; services; study; women
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        item: #7785 of 7819
          id: cord-355935-psnqrdo2
      author: Paez, Antonio
       title: A Spatio‐Temporal Analysis of the Environmental Correlates of COVID‐19 Incidence in Spain
        date: 2020-06-08
       words: 8999
      flesch: 47
     summary: The classical SUR model without spatial effects (from here, SUR-SIM) is a stack of equations as follows: where y t = (y 1t , … , y Nt ) is a N × 1 vector, and in our case y st is the incidence ratio in the province s (s = 1, …, N) the day t (t = 1, …, T); X t is a N × When the null hypothesis is rejected, several alternative specifications have been proposed to include spatial effects (Anselin 1988) .
    keywords: analysis; covid-19; days; disease; effect; humidity; incidence; model; period; population; provinces; temperature; time; variables
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        item: #7786 of 7819
          id: cord-355943-bezpprrk
      author: Li, Y.
       title: Urine Proteome of COVID-19 Patients
        date: 2020-05-06
       words: 4443
      flesch: 46
     summary: There is an urgent need for low-cost and reliable diagnostic techniques to estimate and predict the transition of severe COVID-19 patients from mild COVID-19 ones. key: cord-355943-bezpprrk authors: Li, Y.; Wang, Y.; Liu, H.; Sun, W.; Ding, B.; Zhao, Y.; Chen, P.; Zhu, L.; Li, Z.; Li, N.; Chang, L.; Wang, H.; Bai, C.; Xu, P. title: Urine Proteome of COVID-19 Patients date: 2020-05-06 journal: nan DOI: 10.1101/2020.05.02.20088666 sha: doc_id: 355943 cord_uid: bezpprrk The atypical pneumonia (COVID-19) caused by SARS-CoV-2 is an ongoing pandemic and a serious threat to global public health.
    keywords: author; covid-19; funder; license; medrxiv; patients; peer; preprint; urine; version
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        item: #7787 of 7819
          id: cord-355961-qupxo232
      author: Ndiaye, M.
       title: La maladie à coronavirus COVID-19 en Afrique subsaharienne : la place de la santé au travail
        date: 2020-04-22
       words: 1176
      flesch: 45
     summary: La santé au travail de par sa démarche impliquant tous les acteurs concernés, constitue un formidable outil de prévention et de lutte contre les situations de crise sanitaire comme la pandémie actuelle à coronavirus. Les politiques d'ajustement structurel nées de la crise économique des années 70 et 80, ont permis un développement rapide du secteur informel.
    keywords: covid-19; des; les; travail
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        item: #7788 of 7819
          id: cord-355986-ntovppf8
      author: Chapman, Michael
       title: Systems of Care in Crisis: The Changing Nature of Palliative Care During COVID-19
        date: 2020-08-25
       words: 2764
      flesch: 37
     summary: These systemic changes also trigger responses from care systems, such as those providing palliative care. This paper will examine these impacts through a description of the influence on palliative care systems that have arisen within this pandemic.
    keywords: care; covid-19; palliative; pandemic; responses; systems
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        item: #7789 of 7819
          id: cord-356009-emn2w8if
      author: Roshandel, M. R.
       title: What Specimen Urologists Should Be Most Concerned About ? A Systematic Review and Meta-Analysis
        date: 2020-10-13
       words: 4690
      flesch: 40
     summary: The Journal of infection Persistent shedding of viable SARS-CoV in urine and stool of SARS patients during the convalescent phase SARS-CoV-2 infection does not significantly cause acute renal injury: an analysis of 116 hospitalized patients with COVID-19 in a single hospital Quantitative detection and viral load analysis of SARS-CoV-2 in infected patients Viral load of SARS-CoV-2 in clinical samples. Nevertheless, a lack of concordance between the severity of disease and ICU admission rates in two groups in table 2 indicates heterogeneity of study populations among the studies.
    keywords: cov-2; covid-19; disease; medrxiv; patients; preprint; sars; shedding; studies; urine
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        item: #7790 of 7819
          id: cord-356010-wwzv4tl7
      author: Jolley, Daniel
       title: Pylons ablaze: Examining the role of 5G COVID‐19 conspiracy beliefs and support for violence
        date: 2020-06-21
       words: 3876
      flesch: 32
     summary: Such research provides novel evidence on why and when conspiracy beliefs may justify the use of violence. By empirically testing this assumption, the current research provides a timely and important investigation into the associations between conspiracy beliefs and violence to explore why and when conspiracy beliefs may justifyand igniteviolence.
    keywords: anger; beliefs; conspiracy; covid-19; theories; violence
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        item: #7791 of 7819
          id: cord-356030-bbj4r81i
      author: Haehner, Antje
       title: Predictive Value of Sudden Olfactory Loss in the Diagnosis of COVID-19
        date: 2020-06-11
       words: 2050
      flesch: 49
     summary: Compared to COVID-19 patients without smell loss, they were significantly younger and less severely affected. COVID-19 patients with olfactory loss were significantly younger than those without smell loss (p = 0.04) and had less severe symptoms (Table 1) .
    keywords: loss; olfactory; patients; smell
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        item: #7792 of 7819
          id: cord-356033-zzernh1d
      author: Ruan, Wenly
       title: Changes in Pediatric Endoscopic Practice during the COVID-19 Pandemic: Results from an International Survey
        date: 2020-05-30
       words: 1306
      flesch: 36
     summary: 5 Pediatric endoscopy volumes have been impacted significantly in line with adult practice [6] [7] [8] , with over 80% of pediatric institutions operating at <10% of normal procedural volumes and 98.6% of institutions postponing elective procedures. This is the first study to explore the impact of COVID-19 on pediatric endoscopic practice worldwide and to compare differences across regions and between areas with differing COVID-19 case burdens.
    keywords: cases; covid-19; endoscopy; institutions
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        item: #7793 of 7819
          id: cord-356041-tc2cumv2
      author: Cotrin, Paula
       title: Healthcare Workers in Brazil during the COVID-19 Pandemic: A Cross-Sectional Online Survey
        date: 2020-10-09
       words: 5190
      flesch: 47
     summary: 41, 42 In this scenario, it would be expected that healthcare workers have adequate training to care for patients infected with COVID-19, but most healthcare workers did not receive this training. This study compared the impact of COVID-19 pandemic among three categories of healthcare workers in Brazil: physicians, nurses, and dentists, about workload, income, protection, training, feelings, behavior, and level of concern and anxiety.
    keywords: brazil; covid-19; dentists; healthcare; healthcare workers; nurses; pandemic; physicians; workers
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        item: #7794 of 7819
          id: cord-356054-p0b5hkk0
      author: Mousa, Albeir Y.
       title: My vascular diary on COVID-19 Pandemic and ideal health care settings
        date: 2020-07-28
       words: 287
      flesch: 49
     summary: Initiation of full anticoagulation 11 early on may be beneficial to mitigate the incidence of pulmonary emboli in COVID-19 patients. key: cord-356054-p0b5hkk0 authors: Mousa, Albeir Y.; Nanjundappa, Aravinda title: My vascular diary on COVID-19 Pandemic and ideal health care settings date: 2020-07-28 journal: J Vasc Surg Venous Lymphat Disord DOI: 10.1016/j.jvsv.2020.07.008 sha: doc_id:
    keywords: covid-19; patients
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        item: #7795 of 7819
          id: cord-356055-f2x297r8
      author: Jacobson, Nathan A.
       title: COVID Care Clinic: A Unique Way for Family Medicine to Care for the Community During the SARS-CoV-2 (COVID-19) Pandemic
        date: 2020-10-22
       words: 1894
      flesch: 50
     summary: key: cord-356055-f2x297r8 authors: Jacobson, Nathan A.; Nagaraju, Darshan; Miller, Jennifer M.; Bernard, Matthew E. title: COVID Care Clinic: A Unique Way for Family Medicine to Care for the Community During the SARS-CoV-2 (COVID-19) Pandemic date: 2020-10-22 journal: J Prim Care Community Health DOI: 10.1177/2150132720957442 sha: doc_id: 356055 cord_uid: f2x297r8 The Northwest Family Medicine Clinic was closed for routine patients and converted into an exclusive COVID Care Clinic for the region.
    keywords: care; clinic; covid; medicine; patients
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        item: #7796 of 7819
          id: cord-356056-82bvcuvd
      author: Shaikh, Aasef G.
       title: Cerebellar Scholars’ Challenging Time in COVID-19 Pandemia
        date: 2020-04-16
       words: 1344
      flesch: 50
     summary: There is an urgent need to develop novel platforms to assess and follow ataxic patients remotely, especially because cerebellar patients often require ambulatory care to maintain their autonomy. Clinical features of patients infected with 2019 novel coronavirus in Wuhan Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study Self-reported olfactory and taste disorders in SARS-CoV-2 patients: a cross sectional study The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host-virus infection, and proposed neurotropic mechanisms Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations Conflict of Interest
    keywords: covid-19; novel; patients; time
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        item: #7797 of 7819
          id: cord-356057-87kxlqdc
      author: Chagas, Aline Lopes
       title: Management of Hepatocellular Carcinoma during the COVID-19 Pandemic - São Paulo Clínicas Liver Cancer Group Multidisciplinary Consensus Statement
        date: 2020-10-15
       words: 4365
      flesch: 41
     summary: Patients with chronic liver disease and solitary tumors that are 43 cm in size: J Consider performing surgery for patients who have preserved liver function, have no clinically significant portal hypertension or other comorbidities, are young, and present with favorable locations for resection (19, 21 The indications for LT are also similar to those before the pandemic (18) (19) (20) . The COVID-19 pandemic can significantly impact the management of HCC patients from diagnosis to treatment strategies.
    keywords: cancer; covid-19; hcc; liver; pandemic; patients; risk; treatment
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        item: #7798 of 7819
          id: cord-356061-w7q1i0mj
      author: Bani Hani, Diab A.
       title: Successful Anesthetic Management in Cesarean Section for Pregnant Woman with COVID-19
        date: 2020-06-12
       words: 1930
      flesch: 53
     summary: Use of neuraxial blockade techniques are advised during delivery of COVID-19 patients, whether by vaginal route or CS because these techniques will decrease the cardiopulmonary compromise caused by the stress of labor. COVID-19 FAQs for obstetricians-gynecologists, obstetrics World Health Organization [Internet].
    keywords: anesthesia; covid-19; patient; spinal
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        item: #7799 of 7819
          id: cord-356079-w6cqbya0
      author: Simon, John A.
       title: Editor's perspective: COVID‐19's impact on the remediation industry
        date: 2020-06-09
       words: 1517
      flesch: 38
     summary: Architecture of the SARS coronavirus prefusion spike COVID-19 Environmental Enforcement Discretion Policies: U.S. EPA & 50-State Guide Memorandum: COVID-19 implications for EPA's enforcement and compliance assurance program CalEPA issues statement on compliance with regulatory requirements during the COVID-19 emergency Coronaviruses: An overview of their replication and pathogenesis Executive order no EPA takes action to guide health and safety decisions at cleanup sites during the COVID-19 pandemic Enforcement policy for sterilizers, disinfectant devices, and air purifiers during the coronavirus disease 2019 (COVID-19), public health emergency guidance for industry and Food and Drug Administration staff Memorandum: Interim guidance on site field work decisions due to impacts of COVID-19 States have issued enforcement policies that vary between being more lenient, at least on a case-by-case basis, to more stringent than USEPA's.
    keywords: covid-19; enforcement; environmental; guidance; site; usepa
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        item: #7800 of 7819
          id: cord-356085-rnia7mbq
      author: Gai, Ruoyan
       title: Managing healthcare delivery system to fight the COVID-19 epidemic: experience in Japan
        date: 2020-05-13
       words: 1711
      flesch: 39
     summary: Amid the global pandemic of a novel Coronavirus Disease 2019 (COVID-19), healthcare delivery system is being stretched. This commentary aims to briefly review related policies of Japan in managing healthcare delivery system.
    keywords: covid-19; delivery; healthcare; japan; system
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        item: #7801 of 7819
          id: cord-356122-lzc1ux5z
      author: Fedson, David DS.
       title: Statin treatment of COVID-19
        date: 2020-09-28
       words: 1074
      flesch: 39
     summary: The largest and most detailed study of inpatient statin treatment by Zhang et al also reported that inpatient treatment with angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) did not provide a survival benefit greater than that provided by statin treatment alone [5] . Importantly, survival was significantly better in COVID-19 patients whose ACEI/ARB outpatient treatment was continued in the hospital compared with those whose treatment was discontinued [15] .
    keywords: covid-19; patients; treatment
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        item: #7802 of 7819
          id: cord-356127-xy5tyd7t
      author: Omidi, Negar
       title: Prosthetic heart valves and the COVID‐19 pandemic era: What should we be concerned about?
        date: 2020-09-28
       words: 1550
      flesch: 41
     summary: The Lancet Guidance for diagnosis and treatment of disseminated intravascular coagulation from harmonization of the recommendations from three guidelines Clinical features and treatment of COVID-19 patients in northeast Chongqing Case of the index patient who caused tertiary transmission of COVID-19 infection in Korea: the application of lopinavir/ritonavir for the treatment of COVID-19 infected pneumonia monitored by quantitative RT-PCR Interaction between lopinavir/ ritonavir and warfarin Ritonavir and warfarin interaction Bleeding events following concurrent use of warfarin and oseltamivir by medicare beneficiaries Angiotensinconverting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target Coagulopathy and antiphospholipid antibodies in patients with Covid-19 Viral infections and antiphospholipid antibodies Prosthetic heart valves and the COVID-19 pandemic era: What should we be concerned about? Patients with prosthetic valve replacement with coronavirus disease 2019 (COVID- 19) infection are a challenging subset of patients to manage.
    keywords: covid-19; heart; patients; warfarin
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        item: #7803 of 7819
          id: cord-356131-3at94sle
      author: MacIntyre, Peter D.
       title: Language teachers' coping strategies during the Covid-19 conversion to online teaching: Correlations with stress, wellbeing and negative emotions
        date: 2020-08-22
       words: 6620
      flesch: 46
     summary: It is important to study how these trends play out in the longer term both for language teacher stress and well-being. In addition, ANOVA showed that although approach coping was consistently used across stress groups, avoidant coping increased as stress increased suggesting that there may be a cost to using avoidant coping strategies.
    keywords: approach; coping; covid-19; language; outcomes; pandemic; strategies; stress; teachers; teaching
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        item: #7804 of 7819
          id: cord-356132-1nisyl5r
      author: Wang, Huiyao
       title: The psychological distress and coping styles in the early stages of the 2019 coronavirus disease (COVID-19) epidemic in the general mainland Chinese population: A web-based survey
        date: 2020-05-14
       words: 3023
      flesch: 37
     summary: The population with younger age (F = 102.04), unmarried (t = 15.28), with history of visiting Wuhan in the past month (t = -40.86), with history of epidemics occurring in the community (t = -10.25), more concern with media reports (F = 21.84), perceived more impacts of the epidemic outbreak (changes over living situations, F = 331.71; emotional control, F = 1863.07; epidemic-related dreams, F = 1642.78) and negative coping style (t = 37.41) had higher level of psychological distress. The general mainland Chinese population with unmarried, history of visiting Wuhan in the past month, perceived more impacts of the epidemic and negative coping style had higher level of psychological distress in the early stages of COVID-19 epidemic.
    keywords: covid-19; distress; epidemic; population; style
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        item: #7805 of 7819
          id: cord-356145-1jgc62jt
      author: García‐Gil, Miguel Fernando
       title: Acral purpuric lesions associated with coagulation disorders during the COVID‐19 pandemic
        date: 2020-07-02
       words: 371
      flesch: 45
     summary: These include acral erythematous-purpuric lesions reminiscent of perniosis, which are present in 19% of cases with suspected COVID-19 skin lesions. key: cord-356145-1jgc62jt authors: García‐Gil, Miguel Fernando; Monte Serrano, Juan; García García, Mar; Barra Borao, Verónica; Matovelle Ochoa, Cristina; Ramirez‐Lluch, Mar; Ara‐Martín, Mariano title: Acral purpuric lesions associated with coagulation disorders during the COVID‐19 pandemic date: 2020-07-02 journal: Int J Dermatol DOI: 10.1111/ijd.15041 sha: doc_id: 356145 cord_uid: 1jgc62jt nan Different cutaneous manifestations have been described during the COVID-19 pandemic.
    keywords: covid-19; lesions
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        item: #7806 of 7819
          id: cord-356146-0vqg3r2e
      author: Parsi, Kurosh
       title: Triage of patients with venous and lymphatic diseases during the COVID-19 pandemic – The Venous and Lymphatic Triage and Acuity Scale (VELTAS): A consensus document of the International Union of Phlebology (UIP), Australasian College of Phlebology (ACP), American Vein and Lymphatic Society (AVLS), American Venous Forum (AVF), European College of Phlebology (ECoP), European Venous Forum (EVF), Interventional Radiology Society of Australasia (IRSA), Latin American Venous Forum, Pan-American Society of Phlebology and Lymphology and the Venous Association of India (VAI) This consensus document has been co-published in Phlebology [DOI: 10.1177/0268355520930884] and Journal of Vascular Surgery: Venous and Lymphatic Disorders [DOI: 10.1016/j.jvsv.2020.05.002]. The publications are identical except for minor stylistic and spelling differences in keeping with each journal’s style. The contribution has been published under a Attribution-Non Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0), (https://creativecommons.org/licenses/by-nc-nd/4.0/).
        date: 2020-07-08
       words: 2093
      flesch: 30
     summary: Venous and Lymphatic Triage and Acuity Scale aims to standardise the triage of patients with venous and lymphatic disease or vascular anomalies by providing an international consensus-based classification of clinical categories and triage urgency. Venous and Lymphatic Triage and Acuity Scale aims to standardise the triage of patients with venous and lymphatic disease or vascular anomalies by providing an international consensus-based classification of clinical categories and triage urgency.
    keywords: patients; triage; urgency; vascular; venous
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        item: #7807 of 7819
          id: cord-356150-ivso91ln
      author: Torretta, Sara
       title: Diagnosis of SARS-CoV-2 by RT-PCR Using Different Sample Sources: Review of the Literature
        date: 2020-08-31
       words: 3504
      flesch: 40
     summary: Some procedural details can be adopted to minimize nosocomial transmission: as a fact, Won et al 23 proposed a laboratory-safe and low-cost protocol for COVID-19 detection. The high concordance between nasopharyngeal and saliva samples in detection rate of some respiratory viruses, including coronavirus, 32, 30, 31 and the sole detection of coronavirus in saliva but not in nasopharyngeal aspirates previously reported in some patients pushed a Chinese scientific team 26, 27 to test diagnostic reliability of saliva collection, as alternative diagnostic mean.
    keywords: cov-2; covid-19; nps; ops; patients; pcr; saliva; sars
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        item: #7808 of 7819
          id: cord-356164-y778k3hs
      author: Komiyama, Maki
       title: Smoking Cessation as a Public Health Measure to Limit the Coronavirus Disease 2019 Pandemic
        date: 2020-04-23
       words: 986
      flesch: 48
     summary: The effects of cigarette smoking on the transmission of the virus and worsening of COVID-19 have been less addressed. Cigarette smoking increases the expression of ACE-2 in pulmonary tissues, which could in part account for the increased risk of infection.
    keywords: covid-19; disease; smoking
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        item: #7809 of 7819
          id: cord-356173-8vrw4mag
      author: Liebig, J.
       title: Should international borders re-open? The impact of travel restrictions on COVID-19 importation risk
        date: 2020-10-14
       words: 3983
      flesch: 44
     summary: COVID-19 importation data for NSW was obtained from NSW Health and is not publicly available. While several industries continue to experience economic losses due to the imposed interventions, it is unclear whether the different travel restrictions were successful in reducing COVID-19 importations.
    keywords: australia; country; covid-19; importations; incidence; number; travel
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        item: #7810 of 7819
          id: cord-356174-40k6m7l0
      author: Ducloyer, Mathilde
       title: Complete post-mortem data in a fatal case of COVID-19: clinical, radiological and pathological correlations
        date: 2020-08-06
       words: 2880
      flesch: 42
     summary: Only viral cultures from post-mortem samples would reliably demonstrate viral survival in the deceased. Post-mortem virology studies detected the presence of SARS-CoV-2 (B.1 lineage) in the nasopharynx, plasma, lung biopsies, pleural effusion and faeces confirming the persistence of viral ribonucleic acid 48 h after death.
    keywords: autopsy; coronavirus; covid-19; death; disease; findings; lungs; samples; sars
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        item: #7811 of 7819
          id: cord-356195-5pcaxpp9
      author: Jothimani, Dinesh
       title: COVID-19 and Liver.
        date: 2020-06-15
       words: 3977
      flesch: 41
     summary: Caution needs to be exercised when considering initiation of steroids or other immunosuppressive therapy in liver disease patients e.g.; Severe alcoholic hepatitis, Auto immune hepatitis etc 31 . His PCR remained positive for nearly 2 months and subsequently cleared 72 Literature from SARS-CoV and MERS show that post liver transplant patients on immunosuppression were not at risk for high mortality.
    keywords: ace2; clinical; coronavirus; covid-19; disease; infection; liver; patients; sars; syndrome
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        item: #7812 of 7819
          id: cord-356215-0nypfw48
      author: Hu, Xiaojing
       title: Management practices of emergency departments in general hospitals based on blockage of chain of infection during a COVID-19 epidemic
        date: 2020-09-18
       words: 4391
      flesch: 40
     summary: The balance between meeting the needs of emergency patients during the epidemic as well as promptly screening and safely transferring high-risk infections to avoid cross-infection among doctors, patients, and medical staff has become an important scientific issue which posed great challenges for emergency departments (ED). The admission process for emergency patients is indicated as follows: Professionals of Prevention and Control of Healthcareassociated Infections Department Department visited the ED daily to conduct on-site supervision and improvement, including environment and equipment disinfection, ventilation (such as timely removal of the curtain after a rise in temperature), hand hygiene of medical personnel, and sewage and sewage treatment.
    keywords: control; coronavirus; covid-19; department; emergency; epidemic; infection; patients; prevention; staff
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        item: #7813 of 7819
          id: cord-356217-igm2t7md
      author: Noda, Sakura
       title: Severe COVID-19 initially presenting as mesenteric adenopathy
        date: 2020-10-10
       words: 1599
      flesch: 36
     summary: Notably, no initial clinical symptoms or CT findings suggested COVID-19 respiratory infection. One recent study of adults with COVID-19 identified abdominal imaging findings of bowel wall thickening, pneumatosis, and portal venous gas suggestive of ischemia secondary to small-vessel thrombosis, some confirmed by pathology [3] .
    keywords: boy; cov-2; covid-19; disease; findings
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        item: #7814 of 7819
          id: cord-356235-py38bel4
      author: Jia, Xingwang
       title: Clinical significance of IgM and IgG test for diagnosis of highly suspected COVID-19 infection
        date: 2020-03-03
       words: 1435
      flesch: 60
     summary: The positive rate of COVID-19 nucleic acid was 42.10%. In our study, the positive rate of COVID-19 nucleic acid in the 57 All rights reserved.
    keywords: medrxiv; perpetuity; preprint
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        item: #7815 of 7819
          id: cord-356271-k4ux9yey
      author: Sai Thejeshwar, S.
       title: Precise Prediction of COVID-19 in Chest X-Ray Images Using KE Sieve Algorithm
        date: 2020-08-14
       words: 2700
      flesch: 62
     summary: Though the number of COVID-19 images available is too small, it had no effect on the model as a whole as transfer learning-based feature extraction is implemented and SNN The rapid escalation of COVID-19 virus with 2,397,216 confirmed cases and 162,956 confirmed deaths covering 213 countries, areas or territories, (As on 21 April 2020, 2:00 AM CEST)
    keywords: covid-19; images; model; virus
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        item: #7816 of 7819
          id: cord-356284-n0dhv89q
      author: Bachtiger, Patrik
       title: Machine learning for COVID-19—asking the right questions
        date: 2020-07-10
       words: 1461
      flesch: 39
     summary: The first step to achieving this goal is to define the clinical need for which a solution will improve or transform clinical care. CT also has a well established role as a prognostic tool in many diffuse lung diseases, particularly when combined with clinical data.
    keywords: covid-19; disease; learning; machine; research
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        item: #7817 of 7819
          id: cord-356298-a4p4aca8
      author: Luria, Mijal
       title: "Challenges in the Practice of Sexual Medicine in the Time of COVID-19"
        date: 2020-05-25
       words: 1790
      flesch: 46
     summary: This is the time for the various sex education, sexual health and sexual medicine organizations to align for a common purpose-the validation and expansion of sexual wellbeing in the broadest sense of the word. Heeding this warning All of these factors affect sexual function, as well as the willingness, availability and ability to access sexual medicine care if needed.
    keywords: care; covid-19; health; medicine; patients
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        item: #7818 of 7819
          id: cord-356314-mhkhey2w
      author: Alyami, Mohammad H.
       title: Epidemiology of COVID-19 in the Kingdom of Saudi Arabia: An Ecological Study
        date: 2020-09-17
       words: 3882
      flesch: 49
     summary: Males and adults accounted for the majority of COVID-19 cases in the KSA. The Saudi Ministry of Health report on COVID-19 cases is based on real-time (RT)-PCR obtained through nasopharyngeal swabs, which were processed and validated through a regional lab.
    keywords: cases; covid-19; daily; number; rate; saudi; study
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        item: #7819 of 7819
          id: cord-356363-gea5229c
      author: Kurdi, Amanj
       title: A systematic review and meta‐analysis of the use of renin‐angiotensin system drugs and COVID‐19 clinical outcomes: What is the evidence so far?
        date: 2020-10-20
       words: 2431
      flesch: 27
     summary: Given the continuing controversial and paradoxical clinical studies' findings and hypotheses, we believe it is necessary to continue to evaluate the effects of ACEIs/ARBs on COVID-19 clinical outcomes especially as more randomized studies are reported. 36 Several subgroup analyses were also undertaken to explore the effect of potential confounders on the robustness and sensitivity of combined pooled estimates and included subgroup analyses based on whether the reported measure of effects was crude or adjusted, whether the study was peerreviewed or not, the study's methodological quality as per the risk of bias assessment was performed as well as the continent where TA B L E 3 Meta-analyses pooled estimates with 95%CI of the effects of ACEIs/ARBs on COVID-19 related clinical outcomes None.
    keywords: aceis; angiotensin; arbs; covid-19; outcomes; patients; studies
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