item: #1 of 134 id: cord-000059-5hwqdnx1 author: Tokars, Jerome I. title: Enhancing Time-Series Detection Algorithms for Automated Biosurveillance date: 2009-04-17 words: 4422 flesch: 49 summary: Third, using simple count data does not account for the population at risk, which is generally unknown in these systems and which may vary, especially during crisis situations. Stratifying baseline days into weekdays versus weekends to account for day-of-week effects increased sensitivity for the DoD data but not for the ED data. keywords: additional; alert; algorithm; baseline; best; biosense; cation; chief; counts; daily; data; days; detection; disease; dod; early; effect; expected; facility; health; high; hospital; initial; mean; methods; minimum; modifi; outbreaks; period; public; rate; residuals; sensitivity; specifi; statistic; stratifi; surveillance; syndrome; system; test; threshold; total; value; visits; week; weekdays; weekend cache: cord-000059-5hwqdnx1.txt plain text: cord-000059-5hwqdnx1.txt item: #2 of 134 id: cord-000097-vueo83vk author: Beretta, Chiara title: Prolonged extracorporeal membrane oxygenation therapy for severe acute respiratory distress syndrome in a child affected by rituximab-resistant autoimmune hemolytic anemia: a case report date: 2009-04-01 words: 2847 flesch: 39 summary: What is clear, however, in the case of heavy immunosuppressive therapy, is the importance of strict patient monitoring during and after immunosuppressive therapy and an antimicrobial prophylaxis, particularly for fungal agents and P. jirovecii. [5] treated five pediatric refractory AIHA patients, who achieved a complete remission within 15 to 22 months after rituximab therapy. keywords: admission; aiha; anemia; approval; autoimmune; care; case; children; clinical; count; cyclophosphamide; days; doses; ecmo; exchange; figure; final; following; gas; hemolytic; high; icu; immunoglobulin; immunosuppressive; intensive; manuscript; methylprednisolone; months; normal; patient; pediatric; prolonged; refractory; remission; required; respiratory; rituximab; severe; steroid; therapy; treatment; version cache: cord-000097-vueo83vk.txt plain text: cord-000097-vueo83vk.txt item: #3 of 134 id: cord-000705-w52dc97h author: Ríos, Fernando G title: Lung Function and Organ Dysfunctions in 178 Patients Requiring Mechanical Ventilation During The 2009 Influenza A (H1N1) Pandemic date: 2011-08-17 words: 4860 flesch: 43 summary: This was a multicenter, inception cohort study that included patients aged > 15 years admitted to the ICU with a previous history of influenza-like illness, evolving to acute respiratory failure that required mechanical ventilation during the 2009 winter in the Southern Hemisphere. Positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome: a randomized controlled trial Anzueto A: Tidal volume in mechanical ventilation: the importance of considering predicted body weight Pressure-and Volume-Limited Ventilation Strategy Group: Evaluation of a ventilation strategy to prevent barotrauma in patients at high risk for acute respiratory distress syndrome The Multicenter Trail Group on Tidal Volume reduction in ARDS: keywords: acute; admission; ards; care; cases; clinical; common; count; data; day; days; death; differences; disease; distress; entire; evolution; failure; fluid; frequent; group; h1n1; high; higher; hospital; icu; infection; influenza; injury; intensive; ldh; levels; lung; mechanical; niv; non; novel; organ; oxygenation; pandemic; patients; peep; plateau; pneumonitis; points; pressure; respiratory; severe; study; subgroups; survivors; syndrome; tidal; time; use; values; variables; ventilation; viral; virus; volume cache: cord-000705-w52dc97h.txt plain text: cord-000705-w52dc97h.txt item: #4 of 134 id: cord-001192-zbogocki author: van Meer, Maurits PA title: Idiopathic acute myocarditis during treatment for controlled human malaria infection: a case report date: 2014-01-30 words: 4222 flesch: 39 summary: The first myocarditis manifestations occurred 71 days after the last dose of PfSPZ Challenge, 44 days after the last dose of chloroquine, 57 and 31 days after receiving pre-travel vaccines, 12 days after CHMI by P. falciparum-infected mosquito bites, three days after the onset of a sore throat, and one day after diagnosis of P. falciparum malaria and initiation of treatment for malaria. In the current case the cardiac event occurred during the three days when the subject was receiving curative Malarone treatment for P. falciparum malaria. keywords: abnormalities; acute; basal; bites; blood; cardiac; case; challenge; chemoprophylaxis; chest; chloroquine; chmi; clinical; day; days; diagnosis; dose; ecg; enhancement; experimental; falciparum; function; hepatitis; human; immunization; infected; infection; inferolateral; laboratory; left; levels; malaria; malarone; mid; mild; mosquitoes; mri; myocardial; myocarditis; negative; normal; pain; patients; pfspz; plasmodium; positive; possible; post; range; report; rhinovirus; smear; symptoms; table; throat; treatment; trial; troponin; vaccines; volunteer; ×10 cache: cord-001192-zbogocki.txt plain text: cord-001192-zbogocki.txt item: #5 of 134 id: cord-001262-8s7g2wvd author: Zheng, Guoping title: Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study date: 2014-04-04 words: 4927 flesch: 46 summary: The acute respiratory distress syndrome Acute respiratory distress syndrome: epidemiology and management approaches Mesenchymal stem cells: a promising therapy for the acute respiratory distress syndrome Co-infusion of ex vivo-expanded, parental MSCs prevents life-threatening acute GVHD, but does not reduce the risk of graft failure in pediatric patients undergoing allogeneic umbilical cord blood transplantation A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction Double allogenic mesenchymal stem cells transplantations could not enhance therapeutic effect compared with single transplantation in systemic lupus erythematosus Expanded allogeneic adipose-derived stem cells (eASCs) for the treatment of complex perianal fistula in Crohn's disease: results from a multicenter phase I/IIa clinical trial Age-related decline in the osteogenic potential of human bone marrow cells cultured in three-dimensional collagen sponges Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells Human bone marrow and adipose tissue mesenchymal stem cells: a user's guide Bone marrow-derived mesenchymal stem cells in repair of the injured lung Prevention of endotoxin-induced systemic response by bone marrow-derived mesenchymal stem cells in mice Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1 Autologous transplantation of adipose-derived mesenchymal stem cells markedly reduced acute ischemia-reperfusion lung injury in a rodent model Human mesenchymal stem cells overexpressing the IL-33 antagonist sST2 attenuate endotoxin-induced acute lung injury Systemic human orbital fat-derived stem/stromal cell transplantation ameliorates acute inflammation in lipopolysaccharide-induced acute lung injury Acute respiratory distress syndrome: the Berlin Definition Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome: The acute respiratory distress syndrome network Nichol AD: A randomised controlled trial of an open lung strategy with staircase recruitment, titrated PEEP and targeted low airway pressures in patients with acute respiratory distress syndrome Bronchoalveolar and systemic cytokine profiles in patients with ARDS, severe pneumonia and cardiogenic pulmonary oedema Pathogenetic and predictive value of biomarkers in patients with ALI and lower severity of illness: results from two clinical trials Network NARDSCT: lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury National heart L, blood institute acute respiratory distress syndrome clinical trials N: pathogenetic and prognostic significance of altered coagulation and fibrinolysis in acute lung injury/acute respiratory distress syndrome Significance of von Willebrand factor in septic and nonseptic patients with acute lung injury Acute respiratory distress syndrome N: plasma surfactant protein levels and clinical outcomes in patients with acute lung injury Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect A placebo-controlled, randomized trial of mesenchymal stem cells in COPD Cytological and enzymological characterization of adult human adipocyte precursors in culture Multilineage cells from human adipose tissue: implications for cell-based therapies Mesenchymal stromal cells Adipose-derived mesenchymal stromal cells for chronic myocardial ischemia (MyStromalCell Trial): study design Adipose tissue-derived mesenchymal stem cells have in vivo immunosuppressive properties applicable for the control of the graft-versus-host disease Adipose tissue-derived mesenchymal stem cells are more potent suppressors of dendritic cells differentiation compared to bone marrow-derived mesenchymal stem cells Direct comparison of human mesenchymal stem cells derived from adipose tissues and bone marrow in mediating neovascularization in response to vascular ischemia Cotransplantation of adipose tissue-derived insulin-secreting mesenchymal stem cells and hematopoietic stem cells: a novel therapy for insulin-dependent diabetes mellitus Favorable response to human adipose tissue-derived mesenchymal stem cells in steroid-refractory acute graft-versus-host disease N-glycolylneuraminic acid xenoantigen contamination of human embryonic and mesenchymal stem cells is substantially reversible No alloantibodies against mesenchymal stromal cells, but presence of anti-fetal calf serum antibodies, after transplantation in allogeneic hematopoietic stem cell recipients Platelet lysate from whole blood-derived pooled platelet concentrates and apheresis-derived platelet concentrates for the isolation and expansion of human bone marrow mesenchymal stromal cells: production process, content and identification of active components Autologous serum for isolation and expansion of human mesenchymal stem cells for clinical use In vitro expansion of human mesenchymal stem cells: choice of serum is a determinant of cell proliferation, differentiation, gene expression, and transcriptome stability Development of fully defined xeno-free culture system for the preparation and propagation of cell therapy-compliant human adipose stem cells Submit your next manuscript to BioMed Central and take full advantage of: • Convenient online submission • keywords: acute; adipose; administration; adverse; allogeneic; animal; ards; biomarkers; blood; body; bone; cells; clinical; cultured; data; day; days; differences; disease; distress; dose; effects; efficacy; endotoxin; enrollment; epithelial; events; expansion; failure; figure; follow; free; graft; group; hospital; host; hours; human; il-6; il-8; infusion; injury; intravenous; levels; life; liver; lower; lung; marrow; mesenchymal; mice; mscs; patients; period; placebo; protein; randomized; respiratory; response; saline; serum; significant; stem; studies; study; syndrome; systemic; term; tissue; treatment; trial; weight cache: cord-001262-8s7g2wvd.txt plain text: cord-001262-8s7g2wvd.txt item: #6 of 134 id: cord-002659-566uoozj author: Fujimoto, Yousuke title: Pulmonary inflammation and cytokine dynamics of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during A(H1N1)pdm09 influenza infection date: 2017-08-22 words: 4783 flesch: 45 summary: These results demonstrated that pulmonary inflammation in asthmatic mice is induced beginning in the early phase of A(H1N1)pdm09 infection, which mirrors the finding that A(H1N1)pdm09 infection in asthmatic children induces severe pulmonary complications, including pneumonia, atelectasis, etc., after a shorter incubation period than with seasonal virus infection. key: cord-002659-566uoozj authors: Fujimoto, Yousuke; Hasegawa, Shunji; Matsushige, Takeshi; Wakiguchi, Hiroyuki; Nakamura, Tamaki; Hasegawa, Hideki; Nakajima, Noriko; Ainai, Akira; Oga, Atsunori; Itoh, Hiroshi; Shirabe, Komei; Toda, Shoichi; Atsuta, Ryo; Morishima, Tsuneo; Ohga, Shouichi title: Pulmonary inflammation and cytokine dynamics of bronchoalveolar lavage fluid from a mouse model of bronchial asthma during A(H1N1)pdm09 influenza infection date: 2017-08-22 journal: Sci Rep DOI: 10.1038/s41598-017-08030-w sha: doc_id: 2659 cord_uid: 566uoozj Asthmatic patients present more rapid progression of respiratory distress after A(H1N1)pdm09 influenza infection than after seasonal infection. keywords: a(h1n1)pdm09; a(h1n1)pdm09 infection; a(h1n1)pdm09 mice; asthma; asthmatic; bal; bronchial; cd8; cells; children; contrast; control; control mice; cytokine; days post; early; fig; fluid; groups; higher; ifn; il-6; infected; infection; inflammation; inflammatory; influenza; levels; lower; lung; mice; mock; mouse; p =; pandemic; patients; pulmonary; respiratory; seasonal; severe; study; titres; tnf; viral; virus cache: cord-002659-566uoozj.txt plain text: cord-002659-566uoozj.txt item: #7 of 134 id: cord-002945-29nj4f05 author: Ambrose, Rebecca K. title: In Vivo Characterisation of Five Strains of Bovine Viral Diarrhoea Virus 1 (Subgenotype 1c) date: 2018-01-19 words: 6608 flesch: 47 summary: Predominant BVDV subtype in calves with respiratory disease Eradication of bovine viral diarrhea virus in Germany-diversity of subtypes and detection of live-vaccine viruses Bovine viral diarrhea virus: Global status Genetic and antigenic characterization of bovine viral diarrhea viruses isolated from cattle in Hokkaido Genomic and serological diversity of bovine viral diarrhea virus in Japan Pathogenicity of an Indian isolate of bovine viral diarrhea virus 1b in experimentally infected calves Virulent properties of russian bovine viral diarrhea virus strains in experimentally infected calves Kinetics of single and dual infection of calves with an Asian atypical bovine pestivirus and a highly virulent strain of bovine viral diarrhoea virus 1 Impact of variation in acute virulence of BVDV1 strains on design of better vaccine efficacy challenge models A bovine viral diarrhea virus type 1a strain in China: Isolation, identification, and experimental infection in calves Epidemiological features and economical importance of bovine virus diarrhoea virus (BVDV) infections Lack of virus transmission from bovine viral diarrhoea virus infected calves to susceptible peers Failure to spread bovine virus diarrhoea virus infection from primarily infected calves despite concurrent infection with bovine coronavirus Infectivity of pestivirus following persistence of acute infection Virulence comparison and quantification of horizontal bovine viral diarrhoea virus transmission following experimental infection in calves Distinction between persistent and transient infection in a bovine viral diarrhoea (bvd) control programme: Appropriate interpretation of real-time RT-PCR and antigen-ELISA test results Effects of exposure to bovine viral diarrhoea virus 1 on risk of bovine respiratory disease in Australian feedlot cattle The risk of transmission from sheep experimentally infected with bvdv-1c during the acute phase to bvdv naïve sheep Viral dose and immunosuppression modulate the progression of acute bvdv-1 infection in calves: Evidence of long term persistence after intra-nasal infection Practical significance of heterogeneity among BVDV strains: Impact of biotype and genotype on U.S. control programs Bovine viral diarrhoea virus (BVDV) subgenotypes in diagnostic laboratory accessions: Distribution of BVDV1a, 1b, and 2a subgenotypes Characteristics in the epidemiology of bovine viral diarrhea virus (BVDV) of relevance to control Level and duration of serum antibodies in cattle infected experimentally and naturally with bovine virus diarrhoea virus Real-time polymerase chain reaction as a rapid and efficient alternative to estimation of picornavirus titers by tissue culture infectious dose 50% or plaque forming units Quantitative PCR: A quality control assay for estimation of viable virus content in live attenuated goat pox vaccine Quantification system for the viral dynamics of a highly pathogenic simian/human immunodeficiency virus based on an in vitro experiment and a mathematical model Development and validation of a Q-PCR based TCID(50) method for human herpesvirus 6 Studies of the pathogenesis of bovine pestivirus-induced ovarian dysfunction in superovulated dairy cattle Early reproductive loss due to bovine pestivirus infection Increased reproductive losses in cattle infected with bovine pestivirus around the time of insemination A field investigation of the effects of bovine viral diarrhea virus infection around the time of insemination on the reproductive performance of cattle A single amino acid is critical for the expression of B-cell epitopes on the helicase domain of the pestivirus NS3 protein A Manual for the Primary Animal Health Care Worker; Food and Agriculture Organization (FAO Multiplex real-time RT-PCR detection of three viruses associated with the bovine respiratory disease complex Overall, the concentration of platelets in infected animals were reduced for most BVDV-1c strains on Day 7 and/or Day 14 post infection compared to Day 0. keywords: + +; + −; animals; antibodies; antibody; ao554; bovine; bvdv-1c; bvdv-1c strain; calves; cattle; culture; current; data; day; days; diarrhoea; distribution; experiment; figure; groups; increase; infected; infection; nasal; negative; ns155; overall; pi506; platelets; positive; post; properties; qpcr; respiratory; results; samples; serum; significant; specific; strain; studies; study; subgenotypes; swabs; table; temperature; time; trangie; transmission; trial; viral; virus; viruses; vivo; vr1112; − + cache: cord-002945-29nj4f05.txt plain text: cord-002945-29nj4f05.txt item: #8 of 134 id: cord-002957-gw2cow0d author: Gray, Darren W. title: DIVA metabolomics: Differentiating vaccination status following viral challenge using metabolomic profiles date: 2018-04-05 words: 7446 flesch: 30 summary: Elevated levels of biliverdin and bilirubin and decreased 3-indolepropionic acid in non-vaccinated animals at day 6 p.i. may be associated with increased oxidative stress and reactive oxygen scavenging at periods of peak virus titre. During latter stages of infection, increased levels of N-[(3α,5β,12α)-3,12-dihydroxy-7,24-dioxocholan-24-yl]glycine and lysophosphatidycholine and decreased enterolactone in non-vaccinated animals may reflect suppression of innate immune response mechanisms and progression to adaptive immune responses. keywords: accurate; acid; amrtps; analysis; animals; anti; associated; bilirubin; biological; bovine; bpi3v; brd; calves; cell; challenge; chromatographic; coa; column; compounds; cross; data; day; days; diagnostic; differences; differentiation; disease; diva; early; elevated; enterolactone; extraction; fig; function; gradient; groups; hexahydrohippurate; hilic; identification; igg; immune; increased; indolepropionic; infected; infection; inflammatory; ions; levels; liquid; markers; mass; metabolite; metabolomic; methods; milford; min; model; non; observed; opls; outbreaks; p.i; parent; pca; peak; performance; plasma; post; potential; prior; profiles; profiling; r2x; receptor; relative; respectively; respiratory; responses; retention; run; samples; sampling; score; selection; separation; significant; stages; status; study; supervised; table; technical; test; time; treatment; type; uplc; usa; use; vaccinated; vaccinated animals; vaccination; vaccine; variation; veterinary; viral; virus; waters; wild; window cache: cord-002957-gw2cow0d.txt plain text: cord-002957-gw2cow0d.txt item: #9 of 134 id: cord-003533-8m0vyxq8 author: Jayathilaka, P. G. N. S. title: An outbreak of leptospirosis with predominant cardiac involvement: a case series date: 2019-03-18 words: 4150 flesch: 47 summary: key: cord-003533-8m0vyxq8 authors: Jayathilaka, P. G. N. S.; Mendis, A. S. V.; Perera, M. H. M. T. S.; Damsiri, H. M. T.; Gunaratne, A. V. C.; Agampodi, Suneth Buddhika title: An outbreak of leptospirosis with predominant cardiac involvement: a case series date: 2019-03-18 journal: BMC Infect Dis DOI: 10.1186/s12879-019-3905-7 sha: doc_id: 3533 cord_uid: 8m0vyxq8 BACKGROUND: Severe leptospirosis is known to cause multi organ dysfunction including cardiac involvement. We present a case series of severe leptospirosis with cardiac involvement observed during a period of one month at Colombo-North Teaching Hospital, Sri Lanka. keywords: abdomen; acute; admission; blood; cardiac; case; changes; clinical; count; creatinine; day; days; dengue; diagnosis; ecg; echocardiogram; evidence; fever; fluid; high; history; hospital; illness; infection; intravenous; involvement; lanka; leptospirosis; liver; mild; month; myocarditis; normal; number; output; patients; positive; possible; pressure; protein; reactive; recovery; renal; series; serum; severe; shock; sinus; sri; tachycardia; titre; troponin; urine cache: cord-003533-8m0vyxq8.txt plain text: cord-003533-8m0vyxq8.txt item: #10 of 134 id: cord-005453-4057qib7 author: None title: The 45th Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians – Poster Session date: 2019-07-03 words: 276280 flesch: 51 summary: Goals: In the present study, we describe the frequencies of CRE colonization and analyzed its relationship with development of CRE bacteremia and mortality in two different scenarios: stem cell transplant patients (HSCT) and Leukemia patients. The aim of this study was to analyse a single centre experience with HSCT patients requiring ICU admission and the factors affecting outcome. keywords: +100; +14; +180; +30; +365; +60; +90; /day; /kg; 1,2; 1st; 1x10; 2nd; 95%ci; ab0; abdominal; abnormalities; abo; absence; absolute; abstract; acceptable; access; acid; active; active disease; activity; acute graft; acute gvhd; acute leukemia; acute myeloid; addition; adenovirus; adequate; administration; admission; adolescents; adult patients; adults; advanced; advantage; adverse; advt; aes; affected; affected patients; age group; age range; aged; agents; aggressive; agvhd; aic; aim; albumin; alemtuzumab; alive patients; allele; allo hsct; allogeneic bone; allogeneic cell; allogeneic donors; allogeneic hematopoietic; allogeneic hsct; allogeneic patients; allogeneic stem; allogeneic transplantation; allogenic; allograft patients; alloreactive; alloreactivity; allosct; allosct patients; alternative; aml patients; amounts; amphotericin; analysis; analyze; anemia patients; anti; antibiotic; antibodies; antibody; antifungal; antigen; antileukemic; antithymocyte; antiviral; apheresis; aplasia; aplastic; apoptosis; application; approach; appropriate; approved; april; area; arf; ascs; asct; aspergillosis; aspergillus; assay; assessment; associated; association; atg; auc; august; authors; autograft; autoimmune; autologous; autologous hematopoietic; autologous hsct; autologous patients; autologous stem; autologous transplantation; autophagy; availability; available; average; aza; b cells; bacteremia; bacterial; bal; barr; basal; based; baseline; basis; beam; beginning; beneficial; benefit; best; beta; better; bilirubin; biomarkers; biopsies; biopsy; bkv; blasts; bleeding; blinatumomab; blood; blood cells; blood group; blood patients; blood stem; blood transplantation; bmf; bmi; bmt; body; bone; bone marrow; boost; bortezomib; bos; boys; brain; brentuximab; brincidofovir; brother; bsi; budesonide; bumel; burden; busulfan; calcineurin; calcium; calculated; cancer; cancer cell; candida; candidates; candidemia; candidiasis; capacity; car; cardiac; care; caregivers; cart; carv; cases; category; cause; ccr4; cd10; cd19; cd25; cd34; cd34 cells; cd4; cd45ra; cd52; cd56; cd66b; cd8; cdi; cell collection; cell count; cell death; cell depletion; cell disease; cell dose; cell free; cell function; cell graft; cell infusion; cell levels; cell lines; cell lymphoma; cell mobilization; cell non; cell numbers; cell population; cell products; cell proliferation; cell reconstitution; cell recovery; cell replete; cell source; cell subsets; cell therapy; cell transplantation; cell transplants; cell viability; cells; cellular; cellularity; center; central; centre; cerebral; cfdna; cfu; cgd patients; chain; changes; characterization; characterized; chemosensitive patients; chemotherapy; chest; childhood; children; chimeric; chimeric patients; chimerism; china; choice; chronic graft; chronic gvhd; cidofovir; cik cell; cir; class; classical; classification; clearance; clinical; clinical background; clinical study; clinimacs; cll; clonal; clones; close; cml; cmv; cmv disease; cmv infection; cmv prophylaxis; cmv reactivation; cns; cohort; collected; collection; colonization; colonized patients; colony; combination; combined; common; comorbidities; comparable; compare; comparison; complete; complete donor; complete response; complexity patients; complications; components; composition; concentration; conclusions; conditioning; conditioning regimen; conditions; confidence; confirmed; conflict; congenital; consecutive patients; consensus; consent; consideration; consistent; consolidation; context; continued; continuous; contrast; contribute; control; control group; conventional; conversion; copies; copy; cord; cord blood; correlate; correlation; corresponding; corticosteroid; cost; counseling; count; countries; country; course; cox; cpx-351; cr1; cr2; creatinine; criteria; critical; cross; crp; crs; crucial; cryopreservation; cryopreserved patients; csa; csf; ctls; culture; cumulative; cumulative incidence; curative; curative treatment; cure; current; cutaneous; cvc; cycles; cyclophosphamide; cyclosporine; cystitis; cytarabine; cytogenetic; cytokine; cytomegalovirus; cytometry; cytopenias; cytoreductive; cytotoxicity; daily; damage; dasatinib; data; data patients; database; date; day mortality; days; days post; dcs; death; decades; december; decision; declare; decreased; defibrotide; deficiency; degree; delayed; demographic; demyelinating; dendritic; department; depleted; desensitization; detailed patients; detectable; detection; determination; determined; developed; development; device; dexamethasone; dfs; diagnosis; diarrhea; differences; different; differentiation; difficult; diffuse; direct; discharge; disclosure; disclosure background; disclosure results; discontinuation; disease; disease control; disease free; disease patients; disease progression; disease prophylaxis; disease relapse; disease response; disease status; dismal; disorders; distinct; distribution; dlbcl patients; dli; dmso; dna; donations; donor; donor age; donor cells; donor chimerism; donor cmv; donor graft; donor group; donor lymphocyte; donor source; donor t; donor transplant; donor type; doppler; dosage; dose; dosing; double; dpb1; drug; dsa; ductopenia; duration; dysfunction; e.g.; earlier; early; easix; ebmt; ebv; ecp; ecs; eculizumab; education; effect; effective; effectiveness; effector; efficacy; efs; elafin; elderly; elevated; eligible patients; elisa; elispot; eltrombopag; employee; encephalitis; encephalopathy; encouraging; endothelial; endothelial cells; endpoint; engraftment; enhanced; enriched; enrichment; entire; enzyme; epag; episodes; epstein; equivalent; essential; established; estimate; etanercept; etoposide; european; evaluable patients; evaluation; events; evidence; evs; exact; examination; excellent; exercise; expansion; expected; experience; exposure; expression; extended; extensive; extracorporeal; extramedullary; facs; factors; failure; failure patients; family; fanconi; faster; fatal; favorable; fb2; feasibility; feasible; features; febrile; february; female; ferritin; fertility; fever; figure; final; financial; findings; flow; flt3; flubu; fluconazole; fludarabine; flumel; fluorescence; fmt; fnh; focus; fold; following; followup; forms; foundation; fractions; fractures; free; free survival; freezing; frequency; frequent; fresh; frozen; function; funding; fungal; future; gamma; ganciclovir; gastrointestinal; gcsf; gender; general; generation; genes; genetic; genotype; germany; gi gvhd; global; globulin; good; grade; grade ii; graft; graft failure; graftversus; granulocyte; gray; greater; grfs; group; group b; group patients; growth; guidelines; gut; gvhd grade; gvhd group; gvhd incidence; gvhd patients; gvhd prophylaxis; gvhd rate; gvhd therapy; gvl; hadv; haematopoietic; half; hand; haploidentical; haploidentical donor; haploidentical hsct; haploidentical patients; haploidentical stem; haploidentical transplantation; haplosct; harvest; hazard; hbv; hct; hdct; hdm; hdt; healthy; help; hematological; hematological patients; hematology; hematopoietic cell; hematopoietic stem; hemoglobin; hemolysis; hemorrhage; hepatic; hepatitis; hev; hid; high; high dose; high grade; high mortality; high risk; higher; higher median; highest; histological; historical; history; hiv; hla; hla donor; hlh patients; hma; hodgkin; home; honoraria; hospital; hospitalization; host disease; hours; hscs; hsct =; hsct background; hsct complications; hsct group; hsct methods; hsct outcome; hsct patients; hsct program; hsct recipients; hsct relapse; hsct response; hsct setting; hsct treatment; hsos; human; hypertension; hypothesis; i.v; ibrutinib; icu; identification; ifd; ifn; igg; ii patients; iii; iks; il-15; il-2; image; imaging; immediate; immune; immune cell; immunity; immunodeficiency; immunoglobulin; immunological; immunomodulatory; immunosuppressive; immunotherapy; impact; impaired; impairment; important; improved; improvement; improving; incidence; inclusion; incompatibility; increase; independent; index; india; indications; individual; individual patients; induced; induction; infants; infection; infection patients; inferior; inflammation; inflammatory; influence; information; informed; infusion; inhibition; inhibitors; initial; initiation; injury; inkt; institute; institution; intensity; intensity conditioning; intensive; interactions; interest; intermediate; international; interval; intervention; intestinal; intestinal gvhd; intracellular; intravenous; introduction; invasive; involvement; ips; iqr; iron; irradiation; isa; isolated; isolation; itd; itma; iv acute; january; japan; jazz; july; june; kaplan; karnofsky; karyotype; key; kidney; killer; killing; kinetics; kit; kits; knowledge; known; krp203; laboratory; lack; large; later; ldh; lead; leading; left; length; lesions; letermovir; leukaemia; leukapheresis; leukemia cells; leukemia patients; leukemic; leukocyte; levels; lfs; life; like; likely; limitations; limited; limiting; line; line treatment; lineage; linear; liposomal; literature; little; liver; load; local; logistic; long; longer; loss; lower; ltv; lung; lymphoblastic; lymphocyte; lymphoid; lymphoma patients; lymphomas; lymphoproliferative; main; maintenance; major; majority; making; male patients; males; malignancies; malignant; malignant disease; maltophilia; management; manifestations; mann; manufacturing; march; maria; markers; marrow; marrow transplantation; mass; matched; matching; maternal; mature; maximum; mcl; mds patients; mean; measles; measurements; mechanism; median; median age; median cd34; median cell; median day; median donor; median dose; median duration; median follow; median frequency; median group; median interval; median neutrophil; median number; median os; median overall; median pre; median survival; median time; median treatment; medical; medicine; medium; meier; melphalan; memory; mesenchymal; metabolic; methods; methotrexate; mets; mfd; mfi; mice; microbiological; microbiota; mild; miltenyi; minimal; minimum; minor; minutes; mirna; mismatched; mixed; mlc; mmf; mmud; mnc; mobilization; mobilizers; model; moderate; modified; mofetil; molecular; moment; monitoring; monoclonal; monocytes; mononuclear cells; months; months post; morbidity; mortality; mothers; motion; mpn; mrd; mrd group; mri; mscs; msd; msd hsct; mtx; mucositis; mud; multicenter; multiple; multivariate; multivariate analysis; mutations; mycophenolate; myeloablative; myeloablative conditioning; myelodysplastic; myelofibrosis; myeloid; myeloma patients; n=1; n=10; n=11; n=12; n=13; n=14 patients; n=15; n=2; n=21; n=22; n=23; n=3; n=4; n=5; n=6; n=7; n=8; n=9; national; natural; nausea; naïve; nd hsct; necessary; needed; needs; negative patients; negativity; neoplasms; neuroblastoma; neurological; neutropenia; neutrophil; new; nhl; nih; nivolumab; nk cells; nkg2d; nlr; nma; non; nonmalignant; normal; note; novel; november; novo; npm1; nrm; nucleated; number; objective; observation; observed; obstruction; obtaining; obvious; occlusive; occlusive disease; occurrence; october; offer; offspring; older patients; oncology; ones; ongoing; onset; optimal; option; oral; order; organ; origin; original; outcome; ovarian; overall; overall response; overall survival; oxygen; ozogamicin; p=0.002; p=0.01; paediatric patients; pain; pairs; panel; panobinostat; parameters; parents; partial; participants; particular; pathogenesis; pathological; pathway; patient age; patients; patients background; patients characteristics; patients chronic; patients donors; patients higher; patients median; patients recipients; pattern; pbmcs; pbsc; pcnsl patients; pcr; peak; pediatric hsct; pediatric patients; peptide; percentage; performance; period; peripheral; peripheral blood; peripheral stem; persistent; pet; pfs; pgf patients; pharmaceuticals; phase; phenotype; photopheresis; physical; planned; plasma; platelet; platform; play; plerixafor; plt; plus; pneumocystis; pneumonia; pnh; points; pooled; poor; poorer; population; posaconazole; positive cell; positive patients; positivity; possibility; possible; post; post allo; post hsct; post transplant; potential; ppx; practice; pre; predictive; predictors; prednisone; preemptive; preferred; preliminary; preparation; presence; present; presentation; pressure; pretransplant; pretreated patients; prevalence; prevention; previous; primary; primary disease; primary graft; prior; probability; probable; problems; procedure; process; processes; processing; product; profile; prognosis; program; progression; project; proliferation; prolonged; promising; properties; prophylactic; proportion; prospective; protection; protein; protocol; proven; pt#2; ptcy; ptld; pts; pubertal; pubertal patients; pulmonary; purpose; qol; qpcr; quality; quantitative; rabbit; radiological; radiotherapy; randomized; range; rank; rapid; rare; rate; ratg; ratio; rbc; reaction; reactivation; reasons; received; recent; receptor; reconstitution; records; recovered; recovery; recurrent; red cell; reduced; reduction; reference; refractory; refractory acute; refractory disease; refractory gvhd; refractory patients; regard; regimen; registry; regulation; regulatory; rejection; relapse; relapse incidence; relapse mortality; relapse rate; relapsing; related; relationship; relative; release; relevant; remaining; remission; renal; replacement; reported; reports; rescue; research; residual; residual disease; resistant; resistant patients; resolution; resolved; respect; respiratory; responders patients; response; results; retrospective; retrospective study; review; rfs; rhce; risk acute; risk aml; risk disease; risk factors; risk group; risk patients; risks; rituximab; role; romiplostim; routine; rsv; ruxolitinib; rzf; saa; safety; salvage; samples; sampling; sarcoma; sc patients; scale; scan; scd; schedule; scid; score; screening; second; second transplant; secondary; selected; selection; self; sensitivity; sepsis; september; septic; sequence; sequencing; sequential; series; serology; seropositive; serostatus; serotherapy; serum; sessions; setting; severe; severe acute; severe gvhd; severe patients; severity; sex; sga; shock; short; shorter; shows; sibling; sibling donor; sickle cell; signaling; significant; significant risk; signs; similar; single; sinusoidal; sirolimus; sister; site; size; skin; slightly; small; smx; social; society; software; sos; sources; species; specific; specificity; spectrum; spgf; spleen; splenomegaly; spontaneous; spp; spss; stable disease; stage; staining; standard; start; starting; statistical; status; stay; stem cell; step; steroid; steroid treatment; stimulated; stimulation; storage; strategies; strategy; stromal; strong; studies; study; study background; study group; study patients; study period; subgroup; subjects; suboptimal; subpopulations; subsequent; substantial; subtypes; successful; suffering; sufficient; suitable; superior; support; supportive; suppression; surface; surgical; surveillance; survival; survival rate; survive; survivors; susceptibility; sustained; symptomatic; symptoms; syndrome; system; systemic; t cells; table; tacrolimus; tandem; tapered; tapering; target; targeted; tbi; tcd; tcr; tcrαβ; team; technique; technology; term; term survival; test; testing; thalassemia; thalassemic patients; therapeutic; therapies; therapy; thiotepa; threshold; thrombocytopenia; thrombotic; thymic; thymoglobuline; tim3; times; timing; tissue; titers; tki; tma; tmp; tnc; tnf; tocilizumab; tolerability; tolerance; tolerated; tool; total; total patients; toxicities; toxicity; toxoplasma; tpo; traditional; trail; training; transduced; transduction; transfer; transformation; transformed; transfusion; transient; transplant characteristics; transplant complications; transplant conditioning; transplant cyclophosphamide; transplant disease; transplant high; transplant outcomes; transplant patients; transplant period; transplant recipients; transplant relapse; transplant therapy; transplantation background; transplantation results; transplantation unit; transplantations; transplanted; treatment; treatment option; treatment patients; trec; treg; trend; treosulfan; trial; trm; tumor; tumor cells; type; ucb; ucbt; ultrasound; umbilical; unclear; undergone; underlying; underwent; underwent hsct; unit; univariate; university; unknown; unmanipulated; unrelated; unrelated donor; unrelated hsct; untreated; upfront; upper; uric; urine; usa; use; useful; vaccination; vaccine; valganciclovir; validation; values; variables; variants; varied; variety; vascular; vector; vedotin; vein; veno; versus; vgpr; viability; viable; vip; viral; viremia; virus; viruses; visual; vitamin; vitro; vivo; vod; vod patients; volume; vomiting; voriconazole; vwf; wbc; weekly; weeks; weight; white; whitney; wide; withdrawal; women; work; working; world; worse; wt1; x10; y.o; year os; years; years old; years overall; years post; yield; younger patients; yrs cache: cord-005453-4057qib7.txt plain text: cord-005453-4057qib7.txt item: #11 of 134 id: cord-005460-ezrn8cva author: None title: Physicians – Poster Session date: 2017-07-28 words: 287532 flesch: 53 summary: After three months of treatment patient showed an increase in T cells count (CD3, 411/mmc), and a decrease of toxic metabolites: AXP, 1.652 micromol/ml RBC; dAXP, 0.011 micromol/ml RBC; %dAXP, 0.7 maternal T-cell engraftment persists, despite a good response to the PEG-ADA therapy. Moreover, caspases pathway was significantly activated in thawing CD3+, CD56+ and CD14 + cells: FLICA+ cells % in thawing cells were, respectively, 16.8%, 31.1% and 6.2% vs 3%, 9.7% and o1% in fresh cells. keywords: +100; +15; +28; +30; +60; 0.001; 1,2; 1st; 2nd; 6/10 patients; = ns; abdominal; abl1; abnormalities; absence; absolute; acceptable; access; account; acid; active; active disease; activity; acute graft; acute gvhd; acute leukemia; acute lymphoblastic; acute myeloid; acute patients; acyclovir; ada; addition; additional patients; adenovirus; adequate; adherence; adjusted; administration; admission; adoptive; adult patients; adults; advanced; advanced disease; advantage; adverse; affected patients; aged; agents; aggressive; agvhd grade; ahct; ahr; aic; aim; aims; akt; albumin; alc; alemtuzumab; algorithm; alive; allo hsct; allogeneic group; allogeneic hematopoietic; allogeneic hsct; allogeneic stem; allogeneic transplantation; allogenic; allograft; alloreactivity; allosct; alpha; alternative; amgen; aml patients; amphotericin; analysis; anemia; anti; antibacterial; antibiotics; antibodies; antibody; antifungal; antigen; antigenemia; antileukemic; antithymocyte; antiviral; apheresis; aplasia; aplastic; apoptosis; application; approach; appropriate; april; area; asct; asd; assay; assessment; associated; association; atg; atg group; auc; august; author; auto hsct; autoimmune; autologous; autologous hematopoietic; autologous hsct; autologous patients; autologous stem; autologous transplantation; automated; autosct; availability; available; average; b cell; bacteremia; bacterial; balanced; baltimore; based; baseline; basis; bcg; bcr; bcv; beac; beam; beam group; beam patients; bedside; bendamustine; beneficial; benefit; best; beta; better; bilirubin; biological; biomarkers; biopsies; biopsy; bkv; bladder; blasts; bleeding; blinatumomab; blood; blood cell; blood group; blood stem; blood transplant; body; bone; bone marrow; bortezomib; brain; bridge; brincidofovir; broad; bsbmt; bsi; bucy; burden; busulfan; busulphan; calcineurin; campath; cancer; cancer patients; candidates; capacity; cardiac; care; carmustine; cases; categories; catheter; cause; cbt; cbu; ccr7; ccs; cd16; cd19; cd34; cd34 cell; cd4; cd45ra; cd56; cd62l; cd8; cdi; cdv; cebpa; cell activation; cell acute; cell chimerism; cell collection; cell count; cell depletion; cell disease; cell dose; cell engraftment; cell function; cell graft; cell infusion; cell lines; cell lymphoma; cell mobilization; cell number; cell proliferation; cell recovery; cell replete; cell responses; cell source; cell survival; cell therapy; cell transplantation; cell treatment; cell viability; cells; cellular; center; central; centre; cerebral; cervical; cfu; chain; changes; characterized; chemotherapy; childhood; children; chimerism; choice; chop; chromosome; chronic graft; chronic gvhd; chspcs; ci =; cidofovir; cik; ciprofloxacin; circulating; classical; classification; classified; clearance; clinical; clinicians; clinimacs; cll; cml; cmv; cmv disease; cns; cohort; collected; collection; colony; color; combination; combined; common; comorbidities; comparable; compare; comparison; complement; complete; complete remission; complex; complicated; complications; composition; concentration; conclusion; concomitant; conditioning; conditioning regimen; conditioning therapy; conditions; confidence; confirm; conflict; consecutive days; consecutive patients; consensus; consent; consistent; consolidation; contents; context; continued; continuous; contrast; control; control group; control patients; controversial; conventional; copies; cord; cord blood; correlated; correlation; corresponding; corticosteroids; cost; count; countries; country; course; cox; cpap; cpt; cr group; cr patients; cr1; cr2; creatinine; criteria; critical; cross; crp; crs; crucial; crv; cryopreservation; cryopreserved; csa; csf; csf group; ctla4ig; ctp; culture; cumulative; cumulative incidence; curative; curative treatment; cure; current; cutaneous; cvc; cxcr3; cybor; cycle; cyclophosphamide; cyclosporine; cystitis; cytarabine; cytogenetic; cytokine; cytomegalovirus; cytometry; cytotoxic; cytotoxicity; d100; daily; damage; data; database; date; days; days patients; days post; dcs; death; decades; december; decision; decline; decontamination; decreased; deferasirox; defibrotide; deficiency; deficient patients; degree; delayed; delta; demographic; dendritic; density; dental; department; depleted; depletion; detailed; detection; determined; developed; development; device; dexamethasone; dfs; diagnose; diagnosis; diarrhea; differences; different; difficult; difficulties; diffuse; digestive; discharge; disclosure; discontinuation; disease; disease control; disease free; disease progression; disease prophylaxis; disease relapse; disease response; disease risk; disease status; disorders; disparity; distribution; divided; dlbcl patients; dli; dmso; dna; dnr; dock8 patients; donation; donor; donor cell; donor chimerism; donor engraftment; donor hematopoietic; donor hsct; donor lymphocyte; donor n; donor stem; donor transplantation; donor type; dose; dose chemotherapy; dose therapy; dosing; double; drug; dsa; durable; duration; dynamics; dysfunction; earlier; early; early hsct; ebmt; ebv; ecp; eculizumab; effect; effective; effective treatment; effectiveness; effector; efficacy; efficient; efs; elderly patients; elevated; eligible patients; elisa; eln; encouraging; endoscopy; endothelial; endpoint; engraftment; enriched; enrichment; enterovirus; entire; epidermal; episodes; equal; erythroid; essential; established; estimated; estimation; etoposide; european; evaluable patients; evaluated; evaluation; event; evidence; exact; examination; excellent; excess; existing; expansion; experience; experimental; exposure; expression; extended; extensive; extracorporeal; extramedullary; factors; failed; failure; family; family donor; faster; fatal; favorable; fdg; feam; feasibility; feasible; features; febrile; female patients; females; ferritin; fever; fewer patients; figure; filgrastim; filter; final; financial; findings; flow; flt3; fluconazole; fludarabine; fluid; fold; following; follows; form; fourth; fraction; free; free survival; frequency; frequent; fresenius; function; functioning; fungal; future; gastrointestinal; gcsf; gender; general; generation; generic; genes; germany; girl; global; globulin; goal; good; grade; grade ii; grading; graft; graft failure; graft patients; graftversus; granulocyte; greater; grfs; group; group patients; growth; guidelines; gut; gvhd; gvhd cases; gvhd grade; gvhd group; gvhd incidence; gvhd onset; gvhd patients; gvhd prevention; gvhd prophylaxis; gvhd pts; gvl; haematopoietic; half; hand; haploidentical; haploidentical donor; haploidentical hsct; haploidentical stem; haploidentical transplantation; haplosct; harvest; hazard; hcmv; hct; hdc; hdct; hdt; healing; healthy; help; hematological; hematological patients; hematology; hematopoiesis; hematopoietic cell; hematopoietic stem; hematopoietic transplantation; hemorrhagic; hepatic; hepatitis; herv; hhv-6; high; high dose; high incidence; high mortality; high rate; high relapse; high risk; higher; highest; histological; historical; history; hiv; hla; hlh; hlh patients; hma; hodgkin; home; honoraria; hospital; hospitalization; host disease; hpgv; hpl; hr =; hrt; hsct patients; hsct recipients; hsct setting; hsct treatment; hscts; hsos; hsv; human; hyperleukocytosis; hypertension; i.v; ibrutinib; icu; idelalisib; identification; ifd; ifn; igg; iii; il-2; il-6; image; imaging; imatinib; immediate; immune; immunity; immunodeficiency; immunoglobulin; immunological; immunomodulatory; immunosuppression; immunotherapy; impact; impaired; impairment; implementation; important; improved; improvement; incidence; incompatibility; increased; independent; index; indications; individual; induced; induction; infected; infection; inferior; inflammation; inflammatory; influence; information; informed; infusion; inhibitor; initial; initiation; injury; institute; institution; intensified; intensity; intensity conditioning; intensive; interactions; interest; intermediate; international; interval; intervention; intestinal; intestinal gvhd; intravenous; intravesical; introduced; introduction; invasive; investigation; involved; involvement; ips; iqr; iris; iron; irradiated; irradiation; isolated; issues; italy; itd; iv acute; january; japanese patients; july; june; kaplan; karnofsky; karyotype; kidney; killer; kinase; kinetics; kir; kit; knowledge; known; laboratory; lack; large; later; lead; leading; left; lenalidomide; length; lesions; leukaemia; leukapheresis; leukemia cells; leukemia patients; leukemias; leukemic; leukocyte; levels; lfs; life; ligands; light; like; likely; limitations; limited; line; line treatment; liposomal; literature; little; liver; load; local; logistic; london; long; longer; loss; lower; lung; lymphoblastic; lymphocyte; lymphoid; lymphoma patients; lymphomas; lymphoproliferative; m =; mac; main; maintenance; major; majority; males; malignancies; malignant; malignant disease; management; mann; mantle cell; march; marked; markers; marrow; marrow stem; marrow transplantation; mass; matched; matching; maternal; maximum; mcl; mdf; mds patients; mean; measurements; measures; mechanical; mechanism; median; median age; median cd34; median day; median disease; median dose; median duration; median follow; median hct; median interval; median neutrophil; median number; median os; median overall; median survival; median time; median total; medical; medicine; medium; meeting; meier; mel200; melphalan; memory; mesenchymal; mesenchymal stem; metabolic; method; methotrexate; methylprednisolone; mfd; micafungin; mice; microangiopathy; microbiota; micrornas; migration; mild; minimal; minimum; mir-21; mismatched; missing; mixed; mmf; mmud; mnc; mobilization; mobilizers; modality; model; moderate; modified; mofetil; molecular; moment; monitoring; monoclonal; monocytes; mononuclear; mononuclear cells; months; months post; morbidity; mortality; mouse; mpal patients; mpn; mps; mrd; mri; msc; mscs; msd; mtx; mucosal; mucositis; mud; mud hsct; multicenter; multiple; multivariate; muscle; mutated patients; mutation; mycophenolate; myeloablative; myeloablative conditioning; myelodysplastic; myelofibrosis patients; myeloid; myeloma patients; myeloproliferative; n =; naive; national; natural; nausea; necessary; need; negative; negative patients; neoplasm; nervous; neuroblastoma patients; neurological; neutropenia; neutropenic patients; neutrophil; new; newcastle; nhl; nih; nilotinib; nk cell; nkg2d; non; nonrelapse; normal; note; novel; november; novo; nrm; nucleated; number; nutritional; o0.0001; o0.05; o50; objective; observational; observed; obstruction; occlusive; occlusive disease; occurrence; october; ocular; old; older; oncology; oncology patients; ones; ongoing; onset; optimal; option; oral; organ; organization; origin; original; os p; outcome; outpatient; ovarian; overall; overall response; overall survival; overload; p =; p o0.001; p o0.05; p value; paediatric patients; pain; paneth cell; parameters; parents; partial; particular; party; past; pathogenesis; pathway; patient age; patients; patients alive; patients cd34; patients characteristics; patients median; patients post; patients relapse; pbmcs; pbsc; pcm patients; pcr; pediatric hsct; pediatric patients; peptide; percentage; performance; period; peripheral; peripheral blood; peripheral stem; persistent; pet; pfs; ph+; phase; phenotype; photopheresis; phsct; physical; physicians; picc; pirche; planned; plasma; plasma cell; platelet; platelet engraftment; platform; plerixafor; plt; plus; pneumonia; pnh; po0.01; points; polymerase; ponatinib; poor; poorer; population; positive; positive patients; positivity; possibility; possible; post; post hsct; post sct; post transplant; post treatment; posttransplantation; potential; practice; pre; predictive; predictor; preliminary; preparative; presence; present; presentation; pressure; pretransplant; pretreated; prevalence; prevention; previous; primary; priming; prior; probability; probable; problems; procedure; process; processing; product; profile; progenitor; progenitor cells; prognosis patients; prognostic; program; progression; proliferation; prolonged; promising; prompt; properties; prophylactic; prophylaxis patients; proportion; prospective; protein; protocol; proven; ptcy; ptld; ptld patients; pts; pubertal; pulmonary; purpose; qol; qpcr; quality; quantitative; questionnaire; rabbit; radiotherapy; randomized; range; rank; rapid; rare; rate; rbc; rdw; reaction; reactivation; reactive; reasons; receiving; recent; receptor; recipients; recommendations; reconstitution; records; recovered; recovery; recurrent; red cell; reduced; reduction; reference; refractory disease; refractory gvhd; refractory patients; reg3α; regimen; registry; regular; regulatory; rejection; relapse; relapse group; relapse incidence; relapse mortality; relapse post; relapse rate; relapse risk; related; relationship; relative; release; relevant; reliable; remaining; remission; renal; repeat; replacement; replete; reported; reporting; reports; required; research; residual; residual disease; resistant; resolution; respectively; respiratory; responders; responding; response; response rate; results; retrospective; retrospective study; review; rhtm; risk acute; risk factors; risk group; risk patients; risks; rituximab; role; room; routine; ruxolitinib; saa; safety; salvage; salvage patients; salvage treatment; samples; sanofi; scale; scan; scd; schedule; scheme; school; scid patients; sclerosis; score; screening; second; second hsct; second transplantation; secondary; secretion; selected; selection; self; sensitive; sensitivity; sepax; sepsis; september; septic; sequencing; sequential; series; serology; seronegative; seropositive; serotherapy; serum; setting; severe; severe acute; severe chronic; severe gvhd; severity; sex; sexual; shock; short; shorter; sibling; sickle cell; significant; significant risk; signs; similar; single; sinusoidal; sirolimus; site; situation; size; skin; small; social; society; software; sorafenib; sos; sources; special; specific; specificity; spectra; spectrum; spontaneous; st2; stable disease; stage; standard; standardized; starting; statistical; status; stay; stem cell; steroid; stimulating; stool; strategies; strategy; stratified; stromal; strong; studies; study; study group; subgroups; subjects; subpopulations; subsequent; subsets; substantial; subtype; successful; suffering; suitable; summary; superior; support; supportive; surface; surgery; surgical; surveillance; survey; survival; survival rate; survival time; survivors; sustained; symptomatic; symptoms; syndrome; syndrome patients; system; systemic; t cell; table; tacrolimus; taking; tam; tandem; target; targeted; tbf; tbi; tcd; tcr; team; technique; term; test; test p; testing; testosterone; th17; thalassemia; thalassemia patients; thalidomide; thawed; thawing; therapeutic; therapies; therapy; therapy patients; thiotepa; threatening; thrombocytopenia; thrombotic; thymocyte; thymoglobulin; times; timing; tissue; tki; tli; tma patients; tnc; tnf; tocilizumab; tolerance; topical; total; toxicities; toxicity; toxoplasmosis; tpoa; tract; training; transfusion; transient; transplant cyclophosphamide; transplant group; transplant gvhd; transplant outcomes; transplant patients; transplant treatment; transplantation group; transplantation outcomes; transplantations; transplanted; treating; treatment; treatment group; treatment option; treatment patients; treatment response; tregs; trend; treosulfan; trial; trm; tscm; tslp; tumor; type; typing; tyrosine; ucb; ucbt; ud patients; umbilical; unclear; undergone; underlying; understood; underwent; unit; univariate; universitario; university; unknown; unmanipulated; unrelated; unrelated donor; unrelated hsct; upfront; upper; urd; urine; usa; use; useful; vaccination; validation; value; variables; varied; variety; vegf; ventilation; versus; vgpr; viability; viable; viral; viremia; virus; vivo; vod; volume; voriconazole; washing; wbc; weekly; weeks; weight; white; whitney; withdrawal; women; work; working; world; worse; wound; wt1; year os; year overall; year relapse; year survival; years; years old; years post; yield; younger patients; yrs cache: cord-005460-ezrn8cva.txt plain text: cord-005460-ezrn8cva.txt item: #12 of 134 id: cord-005478-5iu38pr6 author: None title: The 45th Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians – Oral Session date: 2019-07-03 words: 63536 flesch: 53 summary: Commonly reported AEs (≥20% patients) were URTI, AST/ALT elevations, fatigue, nausea and diarrhea. %]) attributed to injection site-related TEAEs. keywords: /kg; 0.001; 1,2; 95%ci; aba; abnormalities; abstract; active; activity; acute; acute gvhd; additional; adult; adult patients; advanced; adverse; aes; age; aged; aim; alive; allogeneic; allosct; alternative; amgen; aml; aml patients; analysis; anemia; anti; antibodies; antibody; antigen; applied; approach; arm; asct; asp0113; assays; assessment; associated; association; asxl1; atg; auc; authors; autologous; available; azacitidine; background; baseline; bcma; bcv; benefit; best; better; blood; bmf; bone; burden; busulfan; car; car t; care; cases; cause; cd19; cd34; cd4; cd8; cell; cell therapy; cell transplantation; cellular; centers; changes; characteristics; chemotherapy; children; chimeric; chimerism; chromosome; chronic; chronic gvhd; cibmtr; cik; cir; clarac; clinical; clones; cmv; cns; cohort; combination; combined; common; comparable; complement; complete; complications; conclusions; conditioning; consecutive; consecutive patients; control; conventional; cord; count; course; cox; cr1; cr2; criteria; crs; cryopreserved; csa; csf; cumulative; curative; current; cycles; cyclophosphamide; cyclosporine; cytogenetic; cytokine; cytometry; data; date; days; death; december; depletion; detectable; determined; development; diagnosis; differences; different; dipss; disclosure; disease; disease relapse; dna; donor; dose; dpb1; drug; duration; dysfunction; early; easix; ebmt; effective; effects; efficacy; eligible; endothelial; endpoint; engraftment; erbb2; european; evaluated; events; evidence; expansion; experience; expression; extensive; factors; failure; figure; findings; flamsa; flow; fludarabine; follow; following; free; free survival; frequent; fresh; function; funding; generation; globulin; good; grade; graft; grfs; group; gvhd; gvl; haplo; haploidentical; hazard; hct; hematologic; hematopoietic; hematopoietic stem; high; high risk; higher; history; hla; honoraria; hospital; host; hscs; hsct; human; hyperbilirubinaemia; ibd; ifd; ifn; igg; iii; image; immune; immunosuppressive; immunotherapy; impact; important; improved; improvement; incidence; increase; independent; index; individual; induction; infection; inflammatory; infusion; inherited; inhibitors; intensity; interest; intermediate; iqr; irradiation; january; jazz; karnofsky; kd025; killer; known; label; large; later; lentiglobin; lentiviral; leukemia; leukemia patients; levels; lfs; life; limited; line; liver; long; lower; lymphoblastic; lymphocyte; lymphoid; lymphoma; mac; main; major; majority; male; malignancies; malignant; markers; marrow; matched; mds; mean; median; median age; median follow; median time; medical; memory; methods; mfc; mice; minimal; mismatched; mll; mmf; mobilization; model; moderate; modified; mofetil; molecular; months; morbidity; mortality; mrd; msd; mud; multicenter; multiple; multivariate; murine; mutation; myc; mycophenolate; myeloablative; myelofibrosis; myeloid; myeloma; n=1; n=3; negative; neutropenia; neutrophil; nhl; nkg2dl; non; novartis; novel; nrm; number; objective; observation; observed; older; ongoing; onset; option; organ; orr; outcome; overall; overall survival; p=0.001; p=0.02; partial; patients; pbsc; pcr; pediatric; pediatric patients; performance; period; peripheral; pfs; pharma; phase; placebo; plasma; platelet; plus; points; poor; population; positive; post; posttransplant; potential; pre; present; previous; primary; prior; procedure; process; production; products; profile; progenitors; prognostic; progression; prophylaxis; proportion; prospective; protein; protocol; ptcy; pts; pulmonary; quality; randomized; range; rare; rate; ratio; reactivation; recent; receptor; recipients; recombinant; reconstitution; recovery; reduced; refractory; regimen; registry; regulatory; relapse; relapse mortality; relapse patients; related; release; remission; renal; reported; research; residual; responders; response; restricted; results; retrospective; ric; risk; risk patients; role; ruxolitinib; safety; samples; score; second; secondary; selected; serum; setting; severe; sex; short; sibling; significant; similar; single; sirolimus; skin; sos; source; specific; standard; status; stem; stem cell; steroid; strategies; strategy; studies; study; subjects; substitution; support; survival; survivors; sustained; symptoms; syndrome; system; t cell; table; target; tbf; tbi; tcr; term; test; thalassemia; therapeutic; therapies; therapy; thiotepa; thrombocytopenia; thymic; time; tki; tma; total; toxicity; transduced; transfusions; transplant; transplantation; treatment; treg; trial; trm; tumor; type; underwent; univariate; university; unrelated; use; vaccine; validation; value; variables; vector; viral; vivo; vod; weeks; years cache: cord-005478-5iu38pr6.txt plain text: cord-005478-5iu38pr6.txt item: #13 of 134 id: cord-005497-w81ysjf9 author: None title: 40th International Symposium on Intensive Care & Emergency Medicine: Brussels, Belgium. 24-27 March 2020 date: 2020-03-24 words: 103795 flesch: 50 summary: Conclusions: This is one of the first studies to demonstrate that abnormal RV function is associated with an increased mortality in ICU patients with pneumonia. The fast efficacy of targeted therapies led some intensivists to use them as rescue therapy for ICU patients. keywords: 1st; 24h; 95%ci; abdominal; ability; abnormal; absence; absolute; abstract; accuracy; acid; acquired; activated; activation; activity; acute; acute care; addition; adjusted; adjustment; administration; admission; admission patients; adult patients; adults; adverse; afxa; age; aged; agents; agreement; aim; aims; airway; aki; aki patients; albumin; analgesia; analysis; anesthesia; angiography; animals; antibiotic; anticoagulation; antimicrobial; antixa; anxiety; aof; apache; application; approach; appropriate; april; ards; area; arf; arrest; arrest patients; arterial; artery; assay; assessment; associated; association; athens; atx; auc; audit; available; average; bacteremia; bacterial; balance; barriers; baseline; bbv; bedside; benefit; better; bilirubin; biomarkers; bleeding; blood; blood pressure; bmi; body; bolus; brain; breathing; bundle; burden; burn; burnout; bypass; cabg; cancer; cardiac; cardiac arrest; cardiac patients; cardiac surgery; cardiopulmonary; cardiothoracic; cardiovascular; care; care hospital; care patients; care unit; cartridge; cases; catheter; cause; cbt; cci; cdi; cells; center; central; centre; cerebral; cfs; challenge; changes; characteristics; characterized; chart; chest; children; chloride; chronic; circuit; circulation; circulatory; citrate; classification; clearance; clinical; clinicians; clot; clotting; cmh; coagulation; coagulopathy; cohort; cohort study; collection; combination; combined; committee; common; community; comorbidities; comparable; compare; comparison; complex; compliance; complications; components; compression; concentration; conclusions; conditions; confidence; consciousness; consecutive patients; consent; consumption; continuous; control; control group; controlled; conventional; coronary; correct; correlation; costs; count; course; cpb; cpr; creatinine; criteria; critical; critical care; cross; crp; crrt; csf; cuff; cultures; cumulative; current; curve; cvc; daily; damage; data; database; dataset; day mortality; days; death; december; decision; decrease; degree; delirium; delivery; demographic; department; design; detecting; detection; determination; development; device; diabetes; diagnosis; diaphragm; diarrhea; difference; difficult; dimer; direct; discharge; disease; distress; distribution; doctors; donors; dose; drug; duration; dysfunction; dysglycemia; earlier; early; ecco; ecg; ecls; ecmo; ecmo patients; ecpr; effect; effective; efficacy; elderly patients; elective; electronic; elevated; elevation; emergency; emergency patients; end; endothelial; endotoxin; endpoint; enteral; episodes; ethics; evaluation; events; evidence; excess; exclusion; existing; expected; experience; exposure; expression; extracorporeal; factors; failure; family; favorable; feasible; features; feedback; female; fever; fibrinogen; figure; filter; final; findings; fio; flow; fluid; follow; fraction; fracture; frail patients; frailty; free; freiburg; frequency; frequent; function; future; gas; gender; general; generation; genes; germany; gfap; glasgow; global; glucose; goal; good; grade; gram; greater; group; group patients; guidelines; half; handover; head; health; healthcare; heart; help; hemodynamic; hemoperfusion; hemorrhage; heparin; higher; higher mortality; highest; history; hospital; hospital admission; hospital cardiac; hospital discharge; hospital mortality; hospital stay; hospitalization; hours; hrs; human; hypertension; hyponatremia; icp; icu admission; icu care; icu discharge; icu length; icu mortality; icu patients; icu population; icu staff; icu stay; icuca; icus; ihca; iii; il-6; ill; illness; immune; immunosuppression; impact; impairment; implementation; important; improved; improvement; imv; incidence; incidents; inclusion; income; increased; independent; index; individual; induction; infection; inflammation; inflammatory; influence; information; informed; infusion; inhalation; initial; initiation; injuries; injury; inpatient; insulin; intake; intensive care; interaction; interval; intervention; intra; intravenous; introduction; intubated; intubation; invasive; involved; involvement; iqr; ir+f; iron; ischemia; italy; january; japan; july; kdigo; ketoacidosis; kidney; knowledge; laboratory; lack; lactate; large; lead; leading; learning; left; length; levels; levosimendan; life; likely; limited; linear; literature; liver; local; logistic; long; longer; los; loss; lower; lps; lung; main; major; majority; making; male; malignancy; management; map; march; markers; mass; max; maximum; mcs; mdr; mean; mean age; measured; measurements; mechanical; median; median icu; medical; medical care; medical patients; medication; medicine; members; membrane; mental; methods; mhla; mice; microstructure; min; minimal; minutes; mixed; mmhg; mmol; model; moderate; modified; mods; monitored; monitoring; monocytes; months; morbidity; mortality; mortality rate; multicenter; multidisciplinary; multiple; multivariate; muscle; music; myocardial; national; necessary; need; negative; neurological; neutrophils; new; news; noise; non; normal; novel; november; number; nurses; nursing; nutritional; obese patients; objective; observational study; occurrence; october; odds; ohca; old; ongoing; onset; ooh; operating; optimal; oral; order; organ; outcome; output; overall; oxygen; oxygenation; p<0.001; p<0.05; pad; pain; pamv; panel; pao; parameters; participants; pathogens; patients; pattern; pci; pct; peak; pediatric; peep; percentage; performance; perfusion; period; perioperative; peripheral; peritonitis; physical; physicians; physiological; pics; placebo; plasma; platelet; pneumonia; poca; point; polymorphism; poor; population; position; positive; possible; post; postoperative; potential; practice; predict; predictive; predictors; prescribed; presence; present; present study; presentation; pressure; prevalence; prevention; previous; primary; prior; problem; procalcitonin; procedure; process; product; prognostic; project; prolonged; promising; properties; proportion; prospective; protein; protocol; psychiatric; psychological; pts; public; pulmonary; pulse; pupillometry; purpose; quality; quantitative; questionnaire; randomized; range; rapid; rate; rats; rbc; rca; reactive; reasons; receiver; recent; record; recovery; reduced; reduction; regional; registered; regression; related; relationship; relative; relevant; reliability; removal; renal; renin; replacement; reported; reports; research; resistance; respect; respiratory; responders; response; results; resuscitation; retinal; retrospective; retrospective study; return; review; rhythm; right; risk; risk factors; risk patients; roc; role; room; rosc; routine; s1p; safety; samples; satisfaction; sbf; sbt; scale; school; score; secondary; sedation; selected; sensitive; sensitivity; sepsis; sepsis patients; sepsis-3; septic; septic shock; septicyte; sequential; series; serum; setting; severe; severe patients; severe sepsis; severity; sex; shock; shock patients; shockable; shorter; significant; signs; similar; simulation; single; size; skin; sleep; small; sofa; solution; specific; specificity; spontaneous; staff; stage; standard; standardized; start; statistical; status; stay; stmv; strategies; strategy; strength; stress; stroke; strong; students; studies; study; study group; study period; subgroup; subjects; subsequent; subset; support; surgery; surgical; surgical patients; survey; survival; survivors; symptoms; syndrome; system; systemic; table; target; tavi; tbi; tbi patients; teaching; team; technique; teg; temperature; term; tertiary; test; testing; tgp; therapeutic; therapies; therapy; thickness; threat; threshold; thrombin; thrombosis; tidal; time; tissue; tone; tool; total; tracheal; tracheostomy; traditional; training; transfusion; transplantation; trauma patients; traumatic; treatment; trend; triage; trial; troponin; tube; type; uch; ultrasound; unit; united; university; university hospital; unknown; urinary; urine; use; useful; uws; validation; value; vancomycin; vap; variability; variables; vasopressor; vein; venous; ventilation; ventricular; vital; volume; vri; ward; wbc; weaning; week; weight; women; work; working; workload; worse; years; δci cache: cord-005497-w81ysjf9.txt plain text: cord-005497-w81ysjf9.txt item: #14 of 134 id: cord-005646-xhx9pzhj author: None title: 2nd World Congress on Pediatric Intensive Care 1996 Rotterdam, The Netherlands, 23–26 June 1996 Abstracts of Oral Presentations, Posters and Nursing Programme date: 1996 words: 72090 flesch: 51 summary: Objective: To assess the normal ,gastric intramucosal pH ~Hi) by tonometry in healthy children Patients and methods: Twelve healthy children (6 males and 6 females) with age rmaged from 6 months to 12 years scheduled for minor plastic or urologic surgery. Pain relief was good (VRS less 2) in 53 children -94.6 % of study patients. keywords: -the; abdominal; abnormal; abnormalities; absence; accurate; acidosis; activity; acute; acute respiratory; additional; adequate; administration; admission; adrenaline; adult; adverse; age; aged; agents; aggressive; ahrf; aim; airway; akbr; albumin; alkalosis; alternative; alveolar; american; analysis; anesthesia; animals; anp; antibiotics; antioxidant; aorta; aortic; application; approach; appropriate; ards; ards patients; areas; arrest; arrival; arterial; arteriosus; artery; artificial; aspiration; assessment; assisted; associated; association; asthma; asthmatic; atrial; atrium; authors; auto; available; average; babies; baby; background; bacterial; balloon; base; baseline; basis; bed; beneficial; benefits; best; better; bilateral; birth; bleeding; block; blood; blood flow; blood pressure; body; bolus; bone; boys; bradycardia; brain; breathing; bronchial; bumetanide; bypass; cardiac; cardiac surgery; cardiopulmonary; cardiovascular; care; care patients; care unit; carotid; cases; categories; catheter; cause; caz; cdh; cells; center; central; cerebral; changes; characteristics; chd; chest; childhood; children; children patients; chronic; circuit; circulation; cld; clinical; close; cmh20; cmv; cns; co2; coagulation; coma; combined; comfort; common; comparable; complete; complex; compliance; complicated; complications; computer; concentration; conclusion; conditions; congenital; consecutive; consent; consequence; constant; continued; continuous; contractility; contrast; control; conventional; correlation; count; course; cpap; cpb; creatinine; criteria; critical; cultures; cvp; cvvh; daily; damage; data; days; death; december; decrease; defect; degree; delayed; delivery; department; dependent; design; deterioration; determination; development; device; diagnosis; differences; different; difficult; direct; disability; discharge; discussion; disease; disorders; distress; distribution; doppler; dosage; dose; doxapram; drug; duration; dysfunction; early; ecg; echo; ecmo; effective; effectiveness; effects; efficacy; efficiency; effort; electrolyte; elevated; elevation; emco; emergency; end; endoscopy; endotracheal; energy; enteral; epinephrine; episodes; equipment; etiology; evaluation; evidence; exact; examination; excessive; exchange; excretion; expenditure; experience; experimental; extracorporeal; factors; failure; fat; features; feeding; female; fever; fi02; filling; final; findings; fio2; flow; fluid; fluoride; flux; fold; following; fontan; formula; fraction; france; frequency; frequent; function; gallbladder; gas; gastric; gcs; general; gestational; girl; goal; good; grade; gradient; greater; group; h20; haemofiltration; half; hand; head; healthy; hearing; heart; hemodynamic; hemorrhage; hepatic; hfo; hfov; high; higher; highest; histamine; hospital; hours; hrs; human; humidity; hypertension; hypothesis; hypoxic; i.v; icp; icu; icus; iii; il-6; ill; ill children; ill patients; illness; immediate; impairment; important; improved; improvement; incidence; increase; index; indication; indicators; induced; infants; infection; infiltrates; inflammatory; influence; information; infusion; inhalation; inhaled; initial; injectate; injury; ino; inotropic; inspired; instability; institution; insufficiency; intake; intensive; intensive care; interval; intervention; intestinal; intracranial; intraosseous; intravenous; introduction; intubated; intubation; invasive; investigation; isoflurane; isolated; january; june; ketamine; knowledge; known; kpa; laboratory; lack; lactate; large; later; left; length; lesions; levels; life; likely; limited; lipid; liquid; little; liver; long; los; loss; lower; lowest; lung; magnitude; main; major; management; map; marked; mask; material; maximal; mcd; mda; mean; mean age; measurements; measures; measuring; mechanical; mechanical ventilation; median; medical; medicine; mee; membrane; meningitis; metabolic; methods; mild; milk; minimal; minutes; mmhg; model; moderate; monitoring; months; morbidity; morphine; mortality; mortality rate; motor; mtx; muf; multiple; muscle; myocardial; n=2; n=3; n=5; n=8; nasal; natural; necessary; need; negative; neonatal; neonates; netherlands; neurological; neuromuscular; newborns; nicu; nitrate; nitric; no2; non; normal; nox; number; nurses; nursing; nutritional; objective; observations; observed; obstruction; old; olt; onset; operation; optimal; oral; order; organ; oscillatory; outcome; output; overall; oxide; oximetry; oxygenation; p<.05; p<0.05; paediatdc; page; pain; paired; pao2; pap; parameters; parenteral; parents; particular; pathology; pathways; patients; pattern; pco2; pcv; peak; pediatric; pediatric icu; pediatric intensive; pediatric patients; peep; performance; perfusion; period; peripheral; peritoneal; permeability; persistent; pfc; phase; phi; pht; physicians; physiological; picu; piglets; pip; plasma; platelet; plv; pneumonia; points; poor; population; positive; possible; post; postoperative; postural; potential; ppm; practice; predictive; predictor; premature; presence; present; presentation; pressure; preterm; prevalence; prevention; previous; primary; prims; prism; problems; procedure; process; prognosis; program; prolonged; prone; prospective; protein; psv; pts; pulmonary; pulmonary hypertension; pulse; pump; purpose; purulent; randomization; randomized; range; rapid; rare; rate; ray; reaction; records; recovery; reduced; reduction; region; regression; related; relationship; release; removal; renal; repair; replacement; report; requirement; rescue; research; resistance; resource; respiratory; respiratory distress; respiratory failure; responders; response; results; resuscitation; retrospective; review; right; risk; role; room; route; routine; rsv; safe; salbutamol; saline; samples; sampling; saturation; scale; scan; score; scoring; screening; second; secondary; secretions; sedation; seizures; selected; selective; sensor; sepsis; septic; septicemia; sequelae; series; serum; setting; severe; severe respiratory; severity; sex; shift; shock; short; shunt; sick; significant; signs; similar; simple; single; site; situations; size; skills; skin; small; snli; sodium; solution; south; special; specific; spontaneous; staff; stage; standard; starting; statistical; status; stay; stenosis; structural; studies; study; subjects; successful; supine; supply; support; surfactant; surgery; surgical; survanta; survey; survival; survivors; symptoms; syndrome; syringe; system; systemic; systolic; table; tachycardia; teaching; team; technique; teico; temperature; terbutaline; term; tertiary; test; tetralogy; therapeutic; therapy; tidal; time; tissue; total; tract; training; transducer; transient; transplantation; transplants; trauma; traumatic; treatment; trials; trough; tsh; tube; tubing; twins; type; ultrasound; underlying; understanding; underwent; unit; university; upper; urinary; urine; use; useful; utilization; values; valve; variables; variance; variation; varied; vascular; vena; venous; ventilated; ventilation; ventilatory; ventricle; ventricular; versus; vessels; vitamin; vkbr; volume; wash; weaning; weeks; weight; white; wide; wks; work; years; young; zone cache: cord-005646-xhx9pzhj.txt plain text: cord-005646-xhx9pzhj.txt item: #15 of 134 id: cord-005727-li8pwigg author: None title: ESICM 2010 MONDAY SESSIONS 11 October 2010 date: 2010-08-31 words: 102900 flesch: 50 summary: Postoperative sedation with both midazolam and dexmedetomidine were effective in suppressing oxidative stress in ICU patients. Poorly controlled pain in the postoperative period can lead to slow recovery and life threatening complications, especially in elderly patients. The use of a tidal volume of 6 ml/kg of predicted body weight is part of the management of patients presenting with ARDS (1) and prevents ventilator induced lung injury in ICU patients undergoing mechanical ventilation (2) . keywords: 1st; abdominal; abnormal; absence; access; accurate; acetaminophen; acidosis; acknowledgment; activation; activities; activity; actual; acute; addition; adhesion; administration; admission; admittance; adult patients; adverse; age; agreement; aim; airway; aki; albumin; algorithm; alternative; anaemia; analgesia; analysis; anesthesia; angiography; animals; anova; antibiotic; anticoagulation; antimicrobial; anxiety; aortic; apache; apc; apoptosis; application; approach; appropriate; approval; april; ards; area; arrest; arterial; artery; aspects; assay; assessment; associated; association; asv; attention; auc; audit; available; average; awareness; bacterial; balance; baseline; bed; bedside; beneficial; benefit; best; better; bias; biomarkers; bland; bleeding; blood; blood glucose; bmi; body; bolus; brain; bsi; bundle; burn; cabg; calibration; capillary; cardiac; cardiopulmonary; cardiovascular; care; care patients; care unit; cases; categories; catheter; cause; ccu; cells; center; central; centre; cerebral; challenge; changes; characteristics; charts; chest; chi; chronic; clearance; clinical; clinicians; clp; cmh; coefficient; cohort; coli; coma; combination; comfort; common; communication; comparison; complete; compliance; complications; concentration; concept; conclusions; conditions; consecutive patients; consultants; context; continuous; contrast; control; control group; conventional; cooling; copd; coronary; correct; correlated; correlation; cost; course; cpis; cpr; crbsi; criteria; critical; critical care; critical patients; cross; crp; crrt; crt; cuff; culture; current; curve; cvc; cytokines; daily; data; database; days; death; december; decision; decrease; degree; delay; delirium; delivery; demographic; density; department; descriptive; detection; determined; developed; development; deviation; device; diabetes; diabetic patients; diagnosis; diastolic; differences; different; difficult; direct; discharge; discomfort; disease; distress; distribution; doctors; dose; drug; duration; dysfunction; earlier; early; ecg; echocardiography; education; effective; effectiveness; effects; efficacy; elderly patients; elective; elevated; emergency; end; endothelial; endotoxemia; endotracheal; environment; epidural; episodes; equipment; errors; esicm; established; estimated; evaluation; events; evidence; exchange; exclusion; experience; experimental; expression; factors; failure; families; family; females; femoral; fever; fibrillation; fig; figure; final; findings; finger; fio; flow; fluid; focus; following; forearm; france; frequency; frequent; functional; gas; gcs; gender; general; general icu; germany; glasgow; global; glucose; glyceamic; goals; good; graft; greater; group; group p; guidelines; half; hand; healthy; heart; help; hemodynamic; hemorrhage; heparin; hepatic; hfo; high; higher; higher mortality; highest; hospital; hospital cardiac; hospital mortality; hospitalization; hours; human; hypernatremia; hypertension; hypoglycaemia; hypothermia; hypovolemia; icp; icu admission; icu discharge; icu length; icu mortality; icu patients; icu stay; icus; il-6; ill; illness; imaging; immune; impact; implementation; important; improved; improvement; improving; incidence; incidents; inclusion; increased; increasing; independent; index; indicator; individual; induced; infants; infection; inflammation; inflammatory; influence; influenza; information; informed; infusion; initial; injury; insertion; instability; insulin; intact; intensive; intensive care; international; intervention; interviews; intestinal; intracranial; intravenous; introduction; intubation; invasive; investigation; involved; ischemia; issues; itu; january; key; kidney; knowledge; known; laboratory; lack; lactate; large; lbnp; lead; leading; learning; left; length; leukocyte; levels; life; likely; limit; limited; linear; literature; little; liver; local; logistic; long; longer; loss; lower; lps; lung; lymphocyte; main; major; majority; making; male; malignancy; management; mann; mannitol; manual; map; marker; matched; maximum; mean; mean age; measured; measurement; mechanical; median; medical; medical patients; medicine; members; membrane; metabolic; methods; mice; microcirculation; microdialysis; microvascular; mild; min; mixed; mmhg; mmol; model; moderate; modified; monitored; monitoring; months; morbidity; mortality; mortality rate; mri; multidisciplinary; multiple; multivariate; muscle; myocardial; n =; national; nava; necessary; need; negative; neurological; neurosurgical; neutrophils; new; niacin; nice; nirs; niv; non; noninvasive; norepinephrine; normal; nosocomial; number; nurses; nursing; objectives; observational; observational study; occlusion; occurrence; october; odds; ohca; ohca patients; old; olt; onsd; onset; operation; optimal; order; organ; outcome; output; overall; oxygen; oxygenation; p =; pain; pao; parameters; participants; particular; patients; pattern; pci; pct; peak; percentage; performance; perfused; perfusion; period; peripheral; phagocytosis; phase; physicians; physiological; picco; pigs; placebo; plasma; platelets; pneumonia; point; poor; population; positioning; positive; possible; post; postoperative; potential; ppv; practice; predictive; predictor; preliminary; prescribing; presence; present; pressure; prevalence; prevention; previous; primary; prior; probe; problems; procalcitonin; procedure; process; products; professionalism; prognosis; program; project; prolonged; prophylaxis; propofol; proportion; prospective; protein; protocol; psv; pts; pulmonary; purpose; quality; quantitative; questionnaire; r =; radial; randomized; range; rapid; rate; ratio; rats; reactive; reason; recent; receptor; recommendations; recorded; recovery; reduced; reduction; reference(s; region; regional; regression; related; relationship; relatives; relevant; reliable; removal; renal; repair; replacement; reported; required; research; resistance; respect; respiratory; respondents; response; results; resuscitation; retrospective; retrospective study; review; rewarming; rhapc; rhythm; rifle; right; risk; risk patients; role; room; routine; safety; sah; saline; samples; sampling; saps; satisfaction; saturation; scale; score; sdf; second; secondary; sedation; sensitivity; sensor; sepsis; septic; septic patients; serum; service; sessions; set; setting; severe; severe sepsis; severity; sham; shock; short; signal; significant; similar; simulated; single; site; skills; skin; small; sodium; sofa; software; solution; sound; specific; specificity; spv; square; staff; standard; starting; state; statistical; status; stay; step; strategies; strategy; stress; stroke; student; studies; study; study group; study period; subjects; sublingual; subsequent; successful; sugar; suggested; support; surface; surgery; surgery patients; surgical; surgical patients; survey; survival; survivors; svo; svv; symptoms; syndrome; system; systemic; systolic; table; target; tbi; tbi patients; teaching; team; teamwork; technique; temperature; term; tertiary; test; tgc; therapeutic; therapies; therapy; thoracic; thought; thrombocytopenia; tidal; time; tissue; tlr2; tnf; tool; total; tptd; tracheostomy; trainees; training; transfer; transfusion; transplantation; trauma; trauma patients; traumatic; treatment; trial; troponin; trs; tube; type; ulcer; underwent; unit; university; unknown; upper; urinary; urine; usa; use; useful; value; vap; variability; variables; variation; vasopressor; venous; ventilated; ventilation; ventilatory; ventricular; vessel; vili; volume; vot; ward; water; weaning; week; weight; whitney; women; work; working; worse; years cache: cord-005727-li8pwigg.txt plain text: cord-005727-li8pwigg.txt item: #16 of 134 id: cord-005777-6rvfsx4p author: None title: PS 0420-0716 date: 2007-08-25 words: 59296 flesch: 50 summary: The aim of this study was to determine the risk factors and mortality rate of acinetobacter baumanii infections in ICU patients. It has been considered to play a role in worsening the prognosis of ICU patients. keywords: 24h; abdominal; acid; acinetobacter; acknowledgement; acs; activation; activity; acute; addition; adequate; administration; admission; adult; adult patients; adverse; aecopd; aeruginosa; age; aim; airway; albicans; amplitude; analysis; animals; anova; antibiotic; anticoagulation; antimicrobial; aortic; apache; applied; approach; appropriate; ards; ards patients; argatroban; arterial; artery; assessment; associated; association; atrial; aureus; available; average; avp; bacteria; balance; baseline; baumannii; bed; best; beta; bleeding; blood; bnp; body; brain; bypass; cabg; calcium; calculated; cancer; candida; candidemia; cardiac; cardiovascular; care; care patients; care unit; cases; catheter; cause; cells; central; centre; changes; characteristics; chest; chpa; chronic; cipc; circuit; clearance; clinical; clotting; cmh2o; coagulation; colistin; collected; colonization; coma; combination; common; community; comparison; competence; compliance; complications; concentrations; conclusion; condition; consecutive patients; continuous; control; control group; conventional; coronary; correlation; cortisol; costs; count; course; cpfa; crbsi; creatinine; criteria; critical; crp; culture; current; curve; cvc; cvvh; cytokines; daily; damage; data; database; day mortality; days; death; december; decrease; degree; demographic; department; deterioration; determined; development; device; diagnosis; dialysis; difference; difficult; discharge; disease; dld; dose; drainage; drug; duration; dysfunction; early; edema; effect; effective; efficacy; elderly; elevated; emergency; empirical; endotoxin; endotracheal; epidural; episodes; esbl; etiology; evaluation; events; evidence; experience; experimental; expression; extent; factors; failure; female; fibrinogen; filter; findings; fio2; flow; fluid; following; force; fraction; free; frequency; frequent; function; gas; gcs; gender; general; germany; glabrata; glasgow; glucose; glutamine; good; gos; gram; greater; group; group patients; guidelines; head; heart; hemodynamic; hemofiltration; heparin; higher; hospital; hospital mortality; hospitalization; hours; hrs; hvg; hypertension; icp; icu; icu admission; icu mortality; icu patients; icu stay; icus; iii; il-6; il-8; ill; illness; iloprost; immune; impact; impaired; implementation; important; improved; improvement; incidence; increase; independent; index; indication; infection; inflammation; inflammatory; information; infusion; inhalation; initial; injury; insulin; intensive; intensive care; intervention; intracranial; introduction; intubated; intubation; invasive; january; laboratory; lactate; large; lead; left; length; levels; life; limited; liver; lma; local; longer; los; loss; lower; lps; lung; main; major; male; management; mann; map; march; maximal; maximum; mean; mean age; measurements; measures; mechanical; mechanical ventilation; median; medical; medical icu; medicine; meropenem; metabolic; methods; mice; minor; minutes; mmhg; mmol; model; monitoring; months; morbidity; mortality; mortality rate; mrna; mrsa; multiple; multivariate; myocardial; n-3; need; negative; neurological; new; non; normal; nosocomial; number; nurse; nursing; observational; observed; odds; old; older; onset; optimal; oral; organ; organisms; outcome; output; overall; oxygen; oxygenation; p<0.001; p<0.05; pao2; parameters; participants; patients; patients hospital; pct; pdt; peak; peep; percentage; perfusion; period; phase; physiological; picco; piece; plasma; platelet; pneumonia; point; poor; population; positioning; positive; possible; postoperative; potential; practice; predictor; presence; present; pressure; previous; primary; prior; problem; procedure; process; profile; prognosis; project; prolonged; prone; prospective; protection; protein; protocol; pts; pulmonary; quality; randomized; range; rate; ratio; rbc; reasons; recent; receptor; recommendations; recruitment; reduced; reduction; regression; related; relationship; relative; release; renal; replacement; report; requirements; research; resistance; respiratory; response; results; resuscitation; retrospective; rfviia; risk; risk patients; role; routine; safety; saline; samples; saps; scale; score; second; secondary; sedation; sepsis; septic patients; septic shock; serum; severe; severe sepsis; severity; shock; shock patients; significant; similar; single; sirs; site; skills; slt; small; sodium; sofa; staff; standard; staphylococcus; state; statistical; status; stay; strategy; stress; stroke; studied; study; study group; study period; superoxide; support; surgery; surgery patients; surgical; surgical icu; surgical patients; survival; survivors; symptoms; syndrome; system; systemic; systolic; table; tbi; team; technique; teg; teicoplanin; temperature; tertiary; test; therapeutic; therapy; time; tissue; tool; total; tracheostomy; training; transfusion; transplantation; trauma; traumatic; treatment; trend; tube; type; underwent; unit; university; usa; use; useful; values; valve; vancomycin; vap; variables; venous; ventilation; ventricular; versus; volume; water; wave; weaning; week; weight; whitney; years cache: cord-005777-6rvfsx4p.txt plain text: cord-005777-6rvfsx4p.txt item: #17 of 134 id: cord-005814-ak5pq312 author: None title: 8th European Congress of Intensive Care Medicine Athens - Greece, October 18–22, 1995 Abstracts date: 1995 words: 179325 flesch: 51 summary: Leukemia inhibitory factor (LIF), a growth factor recently recognised as a polyfunctional cytokine integrated in cytokine networks was measured in unconcentrated BALF of patients from different patient groups. It is difficult to generalize on intensive care units as different patient groups are in different ICUs aud there are great changes from one hospital to another and from one country to another. keywords: + +; -the; 0.001; 1st; 2nd; 3rd; 48h; 546c88; 900c; aaar group; aaar patients; abdominal; abnormalities; absence; absent; absolute; absorption; access; accident; account; accumulation; accuracy; accurate; acid; acidosis; activation; active; activities; activity; actual; acute; acute lung; acute myocardial; acute renal; acute respiratory; adaptation; addition; adequacy; adequate; adhesion; administration; admission; admission patients; adopted; adult patients; adults; advanced; advantages; adverse; aeruginosa; affected; age; aged; aged patients; agents; aggregation; agreement; aid; aim; airway; airway pressure; alarm; albumin; alive; alpha; alterations; altered; alternative; alveolar; ambulance; ami patients; amounts; anaerobes; anaerobic; anaesthesia; analgesia; analysis; anemia; anesthetic; anesthetized; angiography; angiotensin; animals; anova; anp; antagonist; anterior; antibiotics; antibody; anticoagulation; antioxidant; antipyretics; aorta; aortic; apache; apache ii; apnoeic patients; apparatus; appearance; application; applied; approach; appropriate; approval; april; aptt; ards group; ards patients; area; arf; arginine; arrest; arrhythmias; arrival; arterial; arterial blood; arterial pressure; arteries; arterio; artery; artificial; aspects; aspiration; assay; assess; assessment; assist; assisted; associated; association; asthma; atc; atelectasis; athens; attacks; attempts; august; aureus; authors; autologous; automatic; autopsy; available; average; b.a; babies; background; bacteremia; bacterial; balance; balf; balloon; barbiturates; basal; baseline; basis; baxter; bed; beds; bedside; beginning; belgium; beneficial; benefit; bennett; best; beta; better; bicarbonate; bilateral; bilirubin; biochemical; biological; birth; bleeding; blind; blockade; blocker; blood; blood cultures; blood cyanide; blood flow; blood gas; blood lactate; blood loss; blood oxygen; blood pressure; blood samples; blood transfusion; blood volume; blunt; body; bolus; bone; bovine; bpap; bpm; brain blood; breathing; breaths; bronchial; bronchogram; bronchoscopy; bulb; burn; bypass; cabg; calculated; calibration; calories; cancer; candida; cannula; capacity; capillary; carbohydrate; carbon; cardiac; cardiac arrest; cardiac failure; cardiac function; cardiac index; cardiac output; cardiac patients; cardiac surgery; cardiogenic; cardiomyoplasty; cardiopulmonary; cardiovascular; care patients; care unit; carotid; cases; category; catheter; catheterization; cause; cells; cellular; center; central; cephalosporins; cerebral; cerebral blood; certain; cgmp; changes; changes patients; characteristics; chest; chfjv; children; choice; chronic; cip; circuit; circulation; circulatory; cis; cisapride; clamp; clamping; classification; clearance; clinical; clonidine; closed; cmh20; cmv; co2; coagulation; coefficient; cohort; cold; collection; colonization; coma; comatose patients; combination; combined; committee; common; comparable; comparative; comparison; compartment; compensation; complement; complete; complex; compliance; complicated; complications; components; computer; concentration; conclusion patients; conclusions; concomitant; conditions; congenital; congestive; connected; consecutive patients; consequence; considerable; constant; consumption; contamination; content; continued; continuous; contrary; contrast; control group; control patients; controls; contusion; conventional; copd patients; coronary; correct; correlate; correlation; corresponding; cortisol; cost; count; course; cpap; cpb; cpk; cpl; cpr; creatinine; criteria; criterion; critical care; critical patients; cross; csf; cultures; current; curve; cvp; cvvh; cxr; cyanide; cytokines; daily; damage; data; data analysis; date; days; dcm; dead; death; death patients; deceased patients; december; decision; decrease; decreasing; deep; defect; degradation; degree; delay; delayed; delivery; demand; demographic; department; dependent; dependent patients; dept; design; detection; deterioration; determination; determined; development; deviation; device; diabetes; diagnosis; dialysis; diameter; diastolic; diet; differences; different; differential; difficult; dioxide; diphtheria; direct; discharge; discontinuation; discrepancies; discrimination; discussion; disease; disorders; distress; distribution; disturbances; diuresis; do2; do2crit; dobutamine; doctors; dogs; donation; donor; dopexamine; doppler; dosage; dose; double; drainage; drop; drugs; dry; dudng; duodenal; duration; dynamics; dysfunction; dyspnea; earlier; early; easy; ecg; echocardiography; ecmo; edema; eeg; effect; effective; effectiveness; efficacy; efficiency; efforts; effusion; ejection; elderly patients; electrical; electrolyte; elevated; elevation; elisa; embolism; emergency; emergency patients; enalaprilat; end; endocarditis; endoscopy; endothelial; endotoxin; endotracheal; energy; enoxaparin; enteral; entire; entry; environment; enzyme; epidural; epinephrine; episodes; equal; equation; equipment; erythropoietin; esophageal; essential; established; estimate; estimation; etc; etco2; ethical; ethics; etiology; evaluation; events; evidence; evlw; examination; excellent; excessive; exchange; exclusion; excretion; existing; exogenous; experience; experimental; expired; exposure; expression; extensive; extent; external; extracorporeal; extraction; extreme; facilities; factors; failure; failure patients; fall; fast; fatal; fatigue; favourable; february; feedback; feeding; female; femoral; fentanyl; fever; fiberoptic; fibrillation; fibrin; fibrinogen; fick; figure; filling; filter; filtration; final; findings; fio2; fire; flail; flow; fluconazole; fluid; flux; focus; fold; following; foreign; forms; formula; foy; fraction; france; free; frequency; frequent; frg; function; future; ganz; gas; gastric; gastrointestinal; gcs; general; generation; germany; gestational; glasgow; global; glucagon; glucose; glycogen; goal; good; grade; gradient; graft; grafting; gram; granulocytopenic patients; greater; greece; group; group b; group blood; group ii; group l; group patients; guidelines; h20; half; hand; hbr; head; headtrauma patients; healthy; heart; heart failure; heart rate; heart surgery; help; hemodialysis; hemodynamic; hemoglobin; hemorrhage; heparin; hepatic; hepatocytes; heroin; high; high levels; high mortality; high risk; higher; highest; history; hiv; hme; hmef; home; hormonal; hormone; hospital; hospital mortality; hospitalisation; hourly; hours; hrs; hrv; human; humoral; hydrochloride; hypertension; hyperventilation; hypothesis; hypovolemic; hypoxemia; hypoxemic patients; hypoxia; i.c.u; i.v; icg; ich; icp; icpe; icu admission; icu day; icu mortality; icu patients; icu pts; icu stay; icu treatment; icus; identical; iger; ii score; iii; il-6; il-8; ill; illness; ilv; immediate; immune; immunity; impact; impaired; impairment; impedance; important; improved; improvement; incidence; inclusion; increased; index; indications; indicator; indices; indirect; individual patients; indomethacine; induced; induction; infants; infection; inferior; inflammation; inflammatory; inflated; influence; information; informed; infusion; inhalation; inhaled; inhibitor; initial; injured; injuries; injury; inos; inotropes; inotropic; insertion; inspiratory pressure; inspired; institute; institutional; insufficiency; insulin; insult; intensity; intensive; intensive care; interaction; interest; intermittent; internal; interstitial; intervals; interventions; intoxication; intracerebral; intracranial; intramucosal; intraoperative; intrapulmonary; intravascular; intravenous; intrinsic; introduction; intubated patients; intubation; invasive; investigate; investigation; involved; involvement; ippv; ips; ischemia; isoflurane; isolated; isolation; italy; itbv; items; ivh; ivig; january; jejunal; jet; jugular; july; june; kidney; kind; known; kpa; laboratory; lack; lactate; lactate levels; lactatemia; large; later; lavage; lead; left; length; lesions; lethality; leukocyte; levels; life; like; likely; limb; limited; limits; linear; lipid; liquor; literature; little; liver; loading; local; logistic; long; longer; loss; losses; lower; lowering; lowest; lps; lung; lung injury; lung volume; lvad; main; main results; maintain; maintenance; major; majority; making; male; malignant; management; mandatory; manner; mannitol; map; march; marked; markers; mask; massive; material; maximal; maximum; mbar; mean; mean age; mean apache; mean arterial; mean blood; mean duration; mean icu; mean pulmonary; mean time; mean values; measured; measurements; measuring; mechanical; mechanical ventilation; mechanism; median; medical; medication; medicine; membrane; mentioned; mesenteric; metabolic; methods; microbiological; micu; midazolam; middle; mild; min; minor; minutes; mixed; mixture; mmhg; mmol; model; moderate; modified; mof; moisture; molecules; monitoring; months; morbidity; morphine; mortality; mortality rate; mosf; mpap; mpm; mri; mrsa; msec; mucosal; multidisciplinary; multiple; multivariate; murray; muscle; myocardial; n =; n=10; n=5; n=6; n=7; n=9; nasogastric; national; natural; necessary; necrosis; need; negative; negative pressure; neonatal; neonates; neopterin; nerve; nervous; network; neurological; neurological patients; neuromuscular; neutropenic patients; new; newborns; nitric; nitrogen; nmol; no2; no3; non; noninvasive; nonsurvivors; noradrenaline; normal; nosocomial; nox; npe; number; nurses; nursing; nutrition; o.05; obese patients; objectives; observation; observed; observed patients; obstetric patients; obstruction; occlusion; occurrence; old; ones; onset; operating; operation; optimal; order; organ; organ failure; organism; origin; outcome; output; overall; overdose; overload; oxidase; oxidation; oxide; oxygen; oxygenation; oxygenators; p =; p0.1; p<0.001; p<0.05; pace2; paco; paediatric patients; paf; pain; pancreatic; pancreatitis; pao2; paper; parallel; paralysed patients; paralyzed; parameters; parenteral; partial; particular; past; pathogenesis; pathogens; pathological; pathology; patient days; patients; patients ability; patients characteristics; patients conventional; patients hemodynamic; patients methods; patients non; patients outcome; patients peep; patients therapy; patients treatment; pattern; pav; paw; pci; pco; pco2; pcwp; pdr; peak; pediatric; pediatric patients; peep; pel; people; percentage; performance; perfusion; pericardial; period; period patients; peripheral; peritoneal; peritonitis; permeability; peroxidation; persistent; personal; pgi2; phase; phd; phi; physician; physiological; physiology; piece; pigs; pip; placebo; plasma; plasma levels; plasmapheresis; plateau; platelet; play; pleural; pmn; pnct; pneumonia; pneumothorax; po group; po2; points; poisoning; poor; population; porcine; portal; position; positioning; positive; positive blood; positive patients; possibility; possible; postoperative; postoperative patients; postoperative period; potassium; potential; ppa; pph; ppm; practice; precise; predictive; pregnancy; pregnant; preliminary; preload; premature; preoperative; preparation; prescribed; presence; present; present study; presentation; pressure; pressure score; pressure support; pressure time; pressure ventilation; prevalence; prevention; prevents; previous; prevotella; primary; prior; prism; probability; problem; procedure; process; processing; proct; products; professional; profiles; prognosis; program; programme; progressive; prolongation; prolonged; promising; prone; pronounced; properties; prophylaxis; propofol; proportional; prospective; prospective study; prostacyclin; protection; protein; protocol; providing; psb; pseudomonas; psv; ptca; ptr; pts; pulmonary; pulmonary artery; pulmonary blood; pulmonary embolism; pulmonary function; pulmonary gas; pulmonary hypertension; pulmonary pressure; pulmonary vascular; pulse; pump; puritan; purpose; purulent; pvr; pvs patients; pwp; pwt; qrs; qtc; quality; quantitative; question; quick; quinine; r =; radicals; rain; randomized; range; rank; rapid; rare; rate; rats; ray; reach; reaction; ready; reason; recent; recipients; recombinant; records; recovery; recruitment; rectal; reduced; reducing; reduction; reference; reflex; refractory; regard; regimen; regional; registered; regression; regular; regulated; rehabilitation; related; relationship; relative; release; relevant; reliable; removal; renal; renal failure; renin; replacement; reported; requirements; research; residual; resistance; respect; respiratory; respiratory failure; respiratory system; responders; response; responsible; resulted; results; resuscitation; retrospective; return; reversible; review; revision; right; rise; risk; risk patients; role; room; route; routine; rtotlsf; rvef; safe; safety; saline; samples; sao2; saps; saturation; saving; scale; scan; score; scoring; sdd; second; second group; secondary; secretions; sedation; segment; selam-1; selectin; selective; self; sem; sensitive; sensitivity; sepsis; septic patients; septic shock; sequelae; serial; series; serum; service; servo; setting; severe; severe acute; severe ards; severe patients; severe sepsis; severity; sex; shock; shock group; shock patients; short; shorter; shows; shunt; shvo; sicam-1; siemens; significant; significant changes; significant correlation; significant differences; significant increase; signs; similar; simple; simplified; simultaneous; single; sinus; sirs; site; situations; size; sjo; skin; sleep; slight; slope; small; smaller; smokers; sodium; software; soluble; solution; sores; source; space; special; species; specific; specificity; specimens; spectrum; splanchnic; spontaneous; spp; square; stability; stabilization; stable; stable patients; staff; stages; standard; standardized; staphylococcus; start; starting; state; static; statistical; status; stay; stenosis; step; sterile; steroid; stimulation; stimulus; strains; strategies; strategy; stress; stroke; structure; student; studies; study; study group; study period; study results; subarachnoid; subgroups; subjects; subsequent; substances; substantial; successful; sufentanil; suffering; sufficient; supine; supply; support; support ventilation; surface; surfactant; surgery patients; surgical icu; surgical patients; survey; survival; survived; survived patients; surviving; survivors; susceptible; sustained; svo2; svr; swan; symptoms; syndrome; syndrome patients; synthase; system; systemic; systolic; systolic blood; t =; tachycardia; task; tbars; tcd; team; technique; temperature; tendency; terms; tertiary; test; tested; tga; therapeutic; therapy; thermal; thermodilution; thoracic; threatening; thrombolytic; thrombosis; tidal; tidal volume; tile; time; tissue; tnf; tnt; tone; tonometer; tool; total; total respiratory; toxic; toxicity; tpn; tracheal; tracheal pressure; tracheostomy; training; tranmatised patients; transducer; transfer; transfusion; transient; transit; transplantation; transplanted; transport; trauma patients; traumatic; treated; treatment; treatment group; trend; trial; triggering; true; tube; tubing; tumor; type; typical; ulcer; ultrasound; unable; unchanged; underlying; underwent; unit; unit patients; university; unknown; untreated; upper; uptake; urea; urgent; urinary; urine; usa; use; useful; usefulness; usual; values; valve; valvular; vap; variability; variables; variance; variation; varied; vascular; vasoactive; vasoconstriction; vasodilator; vasoreactivity; vco2; vein; velocity; venous; venous blood; venous pressure; ventilated; ventilation; ventilation patients; ventilatory; ventricle; ventricular; verapamil; vessels; victims; vital; vo2; volume; volunteers; vsmc; wall; ward; warm; wave; wbc; wean patients; weaning; wedge; wedge pressure; weeks; weight; white; wide; wilcoxon; withdrawn; wobadd; women; work; worse; wound; xanthine; years; years patients; younger patients; yrs; zeep cache: cord-005814-ak5pq312.txt plain text: cord-005814-ak5pq312.txt item: #18 of 134 id: cord-005816-i54q5gsu author: None title: 10(th) European Congress of Trauma and Emergency Surgery: May 13–17, 2009 Antalya, Turkey date: 2009-08-06 words: 83218 flesch: 50 summary: Liberal utilization of abdominal sonography and abdominal CT scan may reduce missed acute abdomen in abdominal pain patients and appropriate radiological imaging and meticulous evaluation of the X-rays may reduce unnoticed spinal, pelvic and facial fractures in trauma patients. The e-mail noticed us, the presenting author of this abstract (Akira Endo) posted 3 or more abstract as a presenting author, however, the authors of 'Increased mortality in trauma patients with systolic hypertension' believed that Akira Endo in Department of ACCDM, TMDU, Japan surely posted this abstract only. keywords: abdomen; abdominal; abdominal injury; abdominal pain; abdominal trauma; abduction; abscess; absence; access; accident; accuracy; accurate; acs; active; activity; acute; acute abdominal; acute appendicitis; additional; adequate; admission; adult; affected; age; age group; aggressive; aim; aims; ais; alcohol; alternative; amelogenin; amputation; analgesia; analysis; analyze; anastomosis; anatomical; anesthesia; angioembolization; angiography; animals; ankara; ankle; anterior; antibiotic; anxiety; appendectomy; appendicitis; appendix; application; approach; appropriate; area; arterial; artery; articular; asa; assessment; associated; asymptomatic; author; available; average; average age; background; basis; bearing; benign; best; better; bilateral; bile; biliary; bleeding; blood; blunt; blunt trauma; body; bone; bony; bowel; brain; burn; burn patients; calculated; camel; cardiac; care; cases; cast; cause; cells; center; centre; challenging; changes; characteristics; chest; children; choice; cholecystectomy; chronic; classification; clinical; clinical results; closed; closure; cohort; colon; colonic; colostomy; combination; common; comparison; compartment; complaints; complete; complex; complicated; complications; compression; concentrations; conclusion; condition; consecutive patients; conservative; conservative treatment; consolidation; contrast; control; control group; correlation; cost; count; country; course; criteria; critical; cuff; current; cysts; daily; damage; dash; data; days; dcs; death; debridement; december; decision; decrease; deep; defect; definitive; deformity; degree; delayed; demographic; department; development; device; diagnosis; diameter; diaphragmatic; difference; difficult; direct; disaster; discharge; discussion; disease; dislocation; disorder; distal; distribution; diverticulitis; diverticulum; doctors; dorsal; drainage; duodenal; duodenum; duration; early; editor; education; effect; effective; effectiveness; efficient; elbow; elderly; elevated; embolization; emergency; emergency department; emergency surgery; emergent; endoscopic; energy; epigastric; equipment; evaluation; evidence; examination; excellent; excision; exercises; experience; exploration; expression; extensive; external; extremities; extremity; factors; failure; fall; fascial; fasciitis; fast; fecal; female; female patients; femoral; femur; fever; final; findings; fistula; fixation; fixator; flap; flexion; fluid; follow; followed; following; foreign; form; formation; fracture patients; fractures; free; frequent; functional; gallbladder; gastric; gastrointestinal; gcs; gender; general; general surgery; glu; good; grade; grafting; group; gunshot; half; hand; head; head trauma; healing; health; heart; hematoma; hemodynamic; hemorrhage; hems; hepatic; hernia; high; higher; hip; histopathologic; history; hospital; hospital stay; hospitalization; humeral; humerus; hydatic; hypotension; icu; ifn; iii; iliac; ill patients; imaging; immediate; immobilization; immune; impact; implant; important; improved; improvement; incidence; incision; increase; independent; index; indication; individual; infection; inflammatory; inguinal; initial; injured; injuries; injury; injury group; injury patients; injury severity; insertion; insufficient; intensive; internal; intervention; intestine; intra; intraabdominal; intramedullary; intraperitoneal; intravenous; introduction; invasive; involvement; ischemic; isolated; istanbul; january; jaundice; joint; kidney; knee; knowledge; laboratory; laparoscopic; laparotomy; large; lateral; lcp; leakage; left; leg; length; lesions; levels; life; ligament; limb; limited; line; literature; liver; liver injury; local; long; loss; lower; lung; main; major; majority; making; male; management; mass; massive; materials; maxillofacial; maximum; mda; mean; mean age; mean hospital; measures; mechanical; mechanism; meckel; median; medical; medicine; mehmet; melatonin; mesenteric; methods; middle; mild; minimal; mmhg; mobile; model; monitoring; months; morbidity; mortality; mortality rate; motion; motor; mri; multiple; muscle; n =; nac; nail; nailing; national; nausea; necessary; neck; necrosis; necrotizing; need; negative; nerve; neurological; neutrophils; new; non; nonoperative; nonunion; normal; number; nurses; objectives; objects; observation; obstruction; old; omentum; onset; open; operation; option; organ; organ injury; orthopaedic; osteosynthesis; outcome; overall; p =; pain; pancreas; pancreatic; pancreatitis; paper; paracetamol; parameters; partial; pathology; patient group; patients; patients older; pedicle; pelvic; penetrating; people; percent; percentage; percutaneous; perforated; perforation; performance; period; peripheral; peritoneal; peritonitis; phase; physical; physicians; physiological; placement; planned; plastic; plate; points; poor; population; portal; position; positive; possibility; possible; posterior; postoperative; postoperative patients; potential; practice; predictive; prehospital; preoperative; presence; present; presentation; pressure; prevalence; previous; primary; problems; procedure; process; properties; prospective; prosthesis; protein; protocol; proximal; psychiatric; psychological; pulmonary; purpose; pyloric; quadrant; quality; radial; radiographs; radiological; radius; range; rapid; rare; rate; rats; ray; rays; reason; recognition; reconstruction; records; recovery; rectal; rectum; recurrent; reduced; reduction; region; regional; registry; rehabilitation; related; renal; repair; reported; rescue; research; resection; respiratory; response; rest; results; resuscitation; retrospective; retrospective study; review; revision; rib; right; risk; role; room; rotator; routine; rupture; safe; safety; samples; satisfactory; scale; scan; scaphoid; school; score; scoring; screw; second; secondary; self; sensitivity; sepsis; septic; septic patients; series; serum; service; setting; severe; severity; sex; shaft; sham; shock; short; shoulder; shows; sigmoid; significant; signs; similar; simple; single; site; situation; size; skin; slaf; small; sod; soft; space; specific; specimens; spinal; spine; spineboard; spleen; splenectomy; splenic; stability; stabilization; stable; stable patients; stage; standard; standardized; status; stay; stenosis; stenting; stents; stomach; stress; students; studies; study; study group; subjects; subsequent; success; successful; suitable; support; surface; surgeon; surgery; surgical; surgical treatment; survival; suspicion; suture; symptoms; syndrome; system; systemic; systolic; tae; tbi; team; technique; temporary; tenderness; tendon; term; tests; therapeutic; therapy; thickness; thoracic; thoracic trauma; thoracoabdominal; thorax; threatening; thrombocytosis; tibia; time; tissue; tomography; tool; total; tract; traffic; training; transfusion; trauma cases; trauma center; trauma patients; traumas; traumatic; treatment; treatment group; treatment methods; treatment results; triceps; triss; tube; tumor; turkey; type; ulcer; ultrasonography; ultrasound; underwent; uneventful; union; unit; united; university; unstable; upper; urgent; urinary; usa; useful; vac; vacuum; value; variables; vascular; vein; venous; view; volume; vomiting; wall; way; weeks; weight; women; work; wound; years; years old; young cache: cord-005816-i54q5gsu.txt plain text: cord-005816-i54q5gsu.txt item: #19 of 134 id: cord-006182-kck5e1ry author: None title: 17th Annual Meeting, Neurocritical Care Society, October 15–18, 2019, Vancouver, Canada date: 2019-10-01 words: 87787 flesch: 45 summary: Whether a laboratory response in coagulation dosing, laboratory response, hemostatic efficacy and patient outcomes. A project aimed at improving DI management through predictive assessments and DDAVP protocols could potentially improve patient outcomes. keywords: -pcc; -pcc patients; aan; ability; absence; absent; academic; access; accuracy; acid; activity; acute; acute brain; acute care; acute ischemic; additional; adjusted; administration; admission; adult patients; adults; adverse; aed; aged; agent; aggressive; aim; ais; ais patients; alfa; algorithm; amantadine; analysis; andexanet; aneurysmal; angiography; anterior; anti; antibiotics; anticoagulation; antiplatelet; antithrombotic; apache; apixaban; apnea; approach; appropriate; approved; april; aptt; area; arrest patients; arterial; artery; articles; asah patients; assessment; associated; association; atrial; auc; available; average; background; baseline; bdd; bedside; behavioral; benefit; best; better; bilateral; bleeding; blood; brain; brain death; brain injury; brainstem; burden; burst; cangrelor; cardiac; care; care patients; care unit; caregivers; carotid; case; catheter; causes; ceeg; cell; center; central; cerebellar; cerebral; cerebral edema; cerebrovascular; certification; cervical; challenging; changes; characteristics; chart; checklist; children; chloride; chronic; circulation; clinical; clinical outcome; cns; codes; cognitive; cohort; cohort study; coma; comatose; combination; comfort; common; communication; comparison; complete; complex; compliance; complications; comprehensive; conditions; confidence; consciousness; consecutive patients; consistent; continuous; contrast; control; conventional; cooling; correlated; correlation; cortical; cost; countries; course; criteria; cross; cta; current; cvc; daily; data; database; days; dci; dead patients; death; december; decision; decompressive; decrease; dedicated; deep; deficits; degree; delayed; delirium; delta; demographics; department; descriptive; detection; deterioration; determined; development; device; diagnosis; difference; difficult; diffuse; diffusion; discharge; disease; disorders; disposition; donation; doppler; dose; dosing; drug; duration; dvt; dwi; dysfunction; eaca; early; ecmo; edema; education; eeg; eegs; effect; effective; efficacy; electronic; elevated; emergencies; emergency; encephalopathy; end; epilepsy; epilepticus; estimated; etiologies; etiology; evaluation; evd; events; evidence; exam; examination; excellent; expansion; experience; exposure; expression; extensive; external; facility; factors; failure; family; favorable; feasible; features; fellowship; female; fibrillation; final; findings; flow; following; free; frequency; functional; functional outcome; future; gcs; gender; generalized; glasgow; glucose; goal; good; gos; grade; greater; group; guidelines; half; handoffs; head; headache; health; heart; help; hematoma; hemicraniectomy; hemodynamics; hemorrhage; hemostatic; heparin; herniation; higher; highest; history; home; hospital; hospital mortality; hospitalization; hours; hts; hydrocephalus; hyperchloremia; hypertension; hypertonic; hypothermia; hypoxia; ich patients; ich score; icp; icu; iii; ill; illness; imaging; immediate; impact; implementation; important; improved; improvement; incidence; inclusion; increase; independent; index; indication; individual; induced; infarction; infections; information; infusion; initial; initiation; injuries; injury; injury patients; inpatient; instability; institution; intensity; intensive; intensive care; interest; international; interval; intervention; intracerebral; intracranial; intracranial hemorrhage; intravenous; intraventricular; intubated; invasive; involvement; iqr; ischemic; ischemic stroke; ivh; ivig; ivm; january; ketamine; kidney; knowledge; known; laboratory; lack; large; leading; learning; left; length; lesions; levels; levetiracetam; life; likely; limited; literature; lobe; location; logistic; long; longer; los; loss; lower; majority; making; male; malignant; management; markers; maximum; mca; mean; measurements; measures; mechanical; mechanism; median; medical; medications; medicine; meeting; members; metabolic; method; middle; midline; mild; milrinone; minimal; minutes; mmhg; model; moderate; modified; monitoring; months; morbidity; mortality; motor; moyamoya; mri; mrs; mstbi; multicenter; multidisciplinary; multimodal; multiple; multivariate; muscle; nacl; national; ncc; nccu; ncs; necessary; need; negative; network; neurocritical; neurocritical care; neuroimaging; neurointensivist; neurological; neurology; neurosurgical; neurosurgical patients; new; nicardipine; nihss; nlr; nmes; non; normal; normothermia; novel; npi; nsicu; nsicu patients; number; nurses; nursing; objective; observational; observed; occlusion; occurrence; odca patients; odds; old; older; ongoing; onsd; onset; open; optimal; outcome; overall; oxygen; p<0.001; pain; parameters; participants; patient outcomes; patients; patterns; pbto2; pediatric; pediatric patients; performance; perfusion; period; pgb; phase; physicians; placement; plasma; platelet; point; poor; poor outcome; population; positive; possible; post; posterior; postoperative; potential; practice; predictive; predictors; preliminary; presence; present; presentation; pressure; prevalence; prevention; previous; primary; primary outcome; prior; procedure; process; prognosis; prognostication; program; progressive; prolonged; prophylaxis; propofol; proportion; prospective; protein; protocol; pupillary; pupillometry; purpose; qeeg; quality; quantitative; questions; radiographic; range; rankin; rapid; rare; rate; rbc; recent; records; recovery; recurrent; reduced; reduction; reflex; refractory; regression; regx; related; relationship; relative; relevant; renal; repair; repeat; report; required; research; residents; resolution; resource; respiratory; respondents; response; results; retrospective; return; reversal; review; right; risk; rivaroxaban; role; rotterdam; routine; safety; sah; sah patients; saline; sample; sbp; scale; scan; score; sdh; secondary; sedation; seizures; sensitivity; serial; series; serum; sessions; setting; severe; severe tbi; severity; sex; shift; shivering; shock; short; sich; significant; similar; simulation; single; size; small; social; society; sodium; specific; specificity; spinal; spontaneous; square; standard; standardized; state; statistical; status; stay; steroids; strategies; strategy; stroke; stroke patients; studies; study; subarachnoid; subarachnoid hemorrhage; subdural; subjects; subsequent; successful; support; suppression; surgery; surgical; survey; survival; survivors; swd; symptomatic; symptoms; syndrome; system; systemic; target; targeted; tbi patients; tcd; team; technique; technology; temperature; temporal; term; tertiary; test; testing; therapeutic; therapy; thrombectomy; thrombosis; time; timely; timing; tissue; tomography; tool; total; tpa; training; transcranial; transfer; transient; transport; traumatic; traumatic brain; treatment; trend; trials; ttm; txa; type; ultrasound; uncertainty; unclear; underlying; underwent; unique; unit; univariate; university; unknown; usability; use; useful; utility; utilization; values; variables; vascular; vasospasm; ventilator; ventricular; vessel; volume; vpa; vsp; vte; waveforms; weakness; weeks; wilcoxon; wlds; women; worse; worsening; years cache: cord-006182-kck5e1ry.txt plain text: cord-006182-kck5e1ry.txt item: #20 of 134 id: cord-006344-de4dhv4b author: Seitsonen, E. title: Corticosteroids combined with continuous veno-venous hemodiafiltration for treatment of hantavirus pulmonary syndrome caused by Puumala virus infection date: 2006-03-21 words: 2776 flesch: 45 summary: The two Table 2 Platelet counts (PC, ×10 9 /l) and C-reactive protein values (CRP, mg/l) in cases 1 and 2 on consecutive days POS during the period of ICU treatment (days 7-21 POS and 5-15 POS for cases 1 and 2, respectively) survivors who required mechanical ventilation were extubated after 5 days and made a full recovery. [18] demon-strated that at the onset of pulmonary edema, HPS patients have abundant viremia which clears rapidly after the resolution of fever, while respiratory distress may persist. keywords: acute; ards; blood; cases; clinical; continuous; corticosteroid; count; crp; cvvhdf; day; days; edema; epidemica; fever; hantavirus; high; hps; infection; inflammatory; injury; level; lung; mechanical; methylprednisolone; mmhg; nephropathia; pao; patient; platelet; pos; protein; pulmonary; puu; puumala; ratio; recovery; renal; respiratory; response; severe; syndrome; table; therapy; treatment; ventilation cache: cord-006344-de4dhv4b.txt plain text: cord-006344-de4dhv4b.txt item: #21 of 134 id: cord-006391-esnsa4u5 author: None title: Abstracts 5(th) Tripartite Meeting Salzburg/Austria, September 9–11,1982 date: 1982 words: 44873 flesch: 47 summary: Control patients (no ASA) were compared to those receiving 80 or 325 mg. After transplantation patients were followed for a minimum of 3 months and a maximum of 42 months. keywords: abdominal; absorption; accr; accumulation; acid; activity; acute; addition; administration; adrenal; agent; aim; alcohol; allografts; amino; amoebic; amx; analysis; anastomosis; aneurysm; angiography; animals; antibody; antigen; aorta; aortic; area; arterial; arteries; artery; asa; aspirin; associated; atg; atp; aureus; average; balloon; basal; basis; bearing; better; bilateral; bile; biliary; binding; bleeding; blood; blood flow; body; bone; breast; bypass; calcitonin; calcium; cancer; capacity; carbon; carcinoma; cardiac; carotid; cases; cause; cells; cellular; changes; charge; chemotherapy; cholesterol; chronic; cic; circulation; clinical; coagulation; collagen; colonic; combination; common; complete; complications; computer; concentration; conclusion; concrements; conditions; considered; constant; content; contrast; control; control group; coronary; correlated; correlation; creatinine; crystal; cya; cysts; cytochrome; cytology; daily; damage; data; days; decreased; degree; department; dependent; determined; development; dfmo; dhas; diabetes; diabetic; diagnosis; diameter; diet; difference; direct; disease; distal; dna; dncb; dogs; donor; doppler; dose; duct; duodenal; duodenum; duration; early; effect; effective; electrical; elevated; emptying; end; endothelial; energy; enzymatic; enzymes; episodes; esophageal; evaluation; evidence; examination; experimental; factor; failure; fasted; fat; fdp; fed; femoral; fetal; fibrin; fibrinolytic; fibrosis; findings; fistula; flaps; flow; fluid; fold; following; formation; fraction; free; frequent; function; gallbladder; gamma; gastric; glucagon; glucose; glutamine; graft; greater; group; group b; group ii; growth; healing; heart; hemorrhagic; heparin; hepatectomy; hepatic; hepatocytes; high; higher; histamine; histological; histology; hla; hospital; human; hypothesis; i.v; identical; iii; iliac; immune; immunological; immunosuppression; impaired; implantation; important; improved; improvement; incidence; incision; increase; index; individual; induced; infection; influence; infusion; inhibited; inhibition; injury; insulin; intact; intervals; intestinal; intravenous; intubation; invasive; ischemia; islet; isolated; juice; ketone; kidney; known; laboratory; large; lbf; left; lesions; levels; liver; load; local; long; loss; lower; lung; lymphocytes; major; male; malignant; management; marked; material; maximal; maximum; mean; measurements; mechanism; melanoma; metabolic; method; mice; microscopy; min; mitochondrial; mmhg; model; monocytes; months; mortality; muscle; myocardial; necessary; negative; new; non; normal; nucleation; number; nutritional; observed; oesophagitis; operated; operation; order; organ; output; oxygen; p<0.01; pancreas; pancreatic; pancreatitis; parameters; partial; particulate; patency; patients; pattern; peak; peptide; perfusion; period; peripheral; peritoneal; pge2; pgi2; pigs; plasma; platelet; pmol/1; popliteal; portal; positive; possible; postoperative; potassium; potential; preoperative; presence; present; preservation; pressure; previous; primary; prior; procedure; proliferation; prolonged; properties; protein; proximal; psa; pulmonary; purpose; rain; range; rapid; rate; rats; recipients; reconstruction; recurrence; redox; reduced; reduction; reflux; regeneration; rejection; relationship; release; remain; removal; renal; reported; resistance; respiratory; response; results; right; rise; role; saline; salt; samples; scanning; second; secretion; segment; segmental; selective; sem; sensitive; sepsis; septic; serum; severe; sgv; sham; shear; shock; short; shunt; sibp; significant; similar; simple; simultaneous; single; site; size; skin; small; sodium; solution; somatostatin; specific; specimens; sphincter; spleen; splenic; standard; state; stenosis; steroid; stimulation; stomach; stones; strength; stress; studies; study; subjects; subsequent; surface; surgery; surgical; survival; survived; syngeneic; synthesis; synthetase; system; table; technique; test; therapy; thoracic; thrombosis; thyroid; time; tissue; tolerance; total; tract; transfusion; transit; transplantation; transplanted; treatment; trials; true; trypsin; tube; tumor; type; unchanged; underwent; university; urinary; use; useful; vagal; vagotomy; values; valve; vascular; vein; velocity; venous; ventricular; vessels; viability; vitro; vivo; volume; wall; water; weeks; weight; whvp; wound; woundhealing; years cache: cord-006391-esnsa4u5.txt plain text: cord-006391-esnsa4u5.txt item: #22 of 134 id: cord-006444-eq56zhtd author: None title: Abstracts of oral presentations and posters date: 1993 words: 40759 flesch: 49 summary: The shortened NTT was also reflected by a decreased proportion of marrow cells in the post mitotic pool (metas, bands and PMNs) and apparently lengthened blood The application of r-canine G-CSF enhanced the recovery of granulocytes but led to graft failure in dogs receiving a low number of marrow cells. keywords: ability; abmt; absence; activation; active; activities; activity; acute; addition; adherent; administration; advanced; adverse; allogeneic; alpha; aml; amounts; analysis; animals; antibodies; antibody; application; approach; ara; assay; autologous; bacterial; binding; biological; bladder; blast; blood; blood cells; bone; bone marrow; brdu; breast; cancer; capable; capacity; carcinoma; cases; cd14; cd34; cd4; cd56; cell growth; cell lines; cell proliferation; cells; cfu; chain; changes; chemotherapy; children; chronic; clinical; cll; clonogenic; cml; colony; combination; complete; complications; concentrations; consisted; continuous; contrast; control; correlation; counts; course; csf; csf levels; csf receptor; csf therapy; csf treatment; ctx; culture; cycles; cyclic; cyclophosphamide; cytogenetic; cytokines; cytotoxic; cytotoxicity; daily; data; date; days; decrease; degranulation; dependent; depletion; detectable; determined; development; diagnosis; differences; different; differentiation; direct; disease; dna; dogs; dose; drug; duration; early; effective; effector; effects; efficacy; elevated; elisa; endotoxin; engraftment; enhancement; established; evaluable; events; evidence; experiments; expression; factor; failure; febrile; fever; filgrastim; fluid; fold; following; formation; fraction; free; function; gamma; grade; granulocyte; group; growth; growth factor; gvhd; haemopoietic; healthy; hematopoietic; hgfs; high; high dose; higher; hla; hodgkin; hospital; host; hours; hrg; hrs; hsp27; human; i.v; ifn; igf; il-1; il-2; il-3; il-4; il-6; il-8; il6; immune; immunotherapy; important; incidence; incorporation; increase; induced; induction; infection; inflammation; inflammatory; influence; infusion; inhibited; inhibition; inhibits; initial; interferon; interleukin; kinase; lak; later; layers; leukemia; levels; like; lineage; lines; liver; local; long; lower; lps; lung; lymphocytes; lymphoma; macrophages; major; majority; malignant; marker; marrow; maximum; mcg; mds; median; medium; melanoma; metastases; metastatic; method; methug; mice; mif; mnc; mobilization; monocytes; mononuclear; months; mrna; multiple; murine; mxa; myeloid; necrosis; negative; neutropenia; neutrophil; new; nhl; nksf; non; normal; number; observed; order; overall; p21; parameters; partial; patients; pbmc; pbpc; pbsc; pcr; period; peripheral; peripheral blood; phase; phosphorylation; pituitary; plasma; platelet; pmn; population; positive; possible; post; potential; presence; present; pretreatment; primary; prior; production; progenitor; progenitor cells; progression; proliferation; prolonged; protein; protocol; pts; purified; randomized; range; rapid; rate; reaction; recent; receptor; recombinant; reconstitution; recovery; reduced; refractory; regimen; regulation; relapse; related; release; remission; renal; report; responders; response; results; rhg; rhll-4; risk; role; s.c; samples; scd23; scf; scn; scpf; second; secretion; sensitive; sequential; serum; severe; short; significant; sil-2r; similar; single; sites; small; soluble; specific; specimens; stable; stage; starting; stem; stem cells; stimulated; stimulation; stimulatory; stnf; stromal; strong; studies; study; subcutaneous; subsequent; support; surface; surgery; survival; symptoms; syndrome; synthesis; system; systemic; t cells; target; term; tested; tgf; therapeutic; time; tissue; tnf; tnfr; total; toxicity; transfusions; transplantation; treatment; trials; tumor; tumor cells; type; use; uvb; values; vitro; vivo; wbc; weekly; weeks; years; yield cache: cord-006444-eq56zhtd.txt plain text: cord-006444-eq56zhtd.txt item: #23 of 134 id: cord-006849-vgjz74ts author: None title: 27th International Congress of the European Association for Endoscopic Surgery (EAES) Sevilla, Spain, 12–15 June 2019 date: 2019-09-13 words: 222539 flesch: 45 summary: Day after surgery patient was asymptomatic, got full oral diet. Methods: From January 2001 to March 2005 all characteristics of surgical patients with diverticular and colon adenocarcinoma colovesical fistulae were reviewed. keywords: 0.001; 1st; 3d laparoscopic; 3rd; 4th; 5th; abdomen; abdominal; abdominal approach; abdominal cavity; abdominal ct; abdominal hernia; abdominal pain; abdominal surgery; abdominal surgical; abdominal wall; ability; ablation; abscess; abscesses; absence; absorbable; accepted; access; access laparoscopic; access surgery; accessory; account; accuracy; accurate; achalasia; acid; activity; acute; additional; adenocarcinoma; adenoma; adequate; adhesions; adjacent; adjuvant; administration; admission; adrenal; adult; advanced; advanced laparoscopic; advantages; adverse; affected; age; aged; aim; aims; ajcc; algorithm; alternative; american; analgesia; analysis; anastomosis; anatomical; anatomopathological; anatomy; anesthesia; aneurysm; angiography; angle; animal; anterior; anterior resection; anti; antibiotics; antireflux; anus; aortic; appearance; appendectomy; appendiceal; appendicitis; appendix; application; applied; approaches; appropriate; april; area; arm; arms; arterial; artery; asa; ascites; aspects; aspiration; assessment; assistant; assisted; assisted surgery; associated; association; atypical; augmented; authors; available; average; awareness; axillary; axis; background; bag; balloon; band; barbed; bariatric patients; bariatric surgery; baseline; basic; benefits; benign; best; better; better results; bilateral; bile; biliary; billroth; biopsies; biopsy; bleeding; blood; blood loss; blue; blunt; bmi; bmi patients; body; bowel; box; branches; breast; bypass; camera; cancer patients; cancer surgery; cancer treatment; cancers; capsule; cardia; care; careful; case report; case series; cases; catheter; cause; cava; cavity; cbd; celiac; cells; center; centre; certain; cervical; challenges; challenging; changes; channels; characteristics; chemoradiotherapy; chemotherapy; chest; child; choice; cholangiography; cholecystitis; choledocholithiasis; cholelithiasis; chronic; circular; circumstances; cirrhosis; cirrhotic patients; classification; classified; clavien; clear; clinical; clinical case; clinicopathological; clip; clipping; closed; closure; cme; cohort; colic; colitis; collection; colon; colon cancer; colon surgery; colonic; colonoscopy; colorectal cancer; colorectal patients; colorectal surgery; colostomy; colovesical; combination; combined; committee; common; communication; comparable; compare; comparison; complaints; complete; complete laparoscopic; complete resection; complete surgical; completion; complex; complexity; complicated; complications; component; compression; computer; concept; conclusion; concomitant; condition; confirmed; congenital; consecutive patients; consensus; conservative; constipation; contact; content; continuous; contrast; control; control group; controversial; conventional laparoscopic; conversion; conversion rate; converted; cooperative surgery; correct; correlation; cosmetic; cosmetic results; cost; countries; course; cox; creation; criteria; critical; crp; crural; ct scan; curative; current; curvature; curve; cutting; cvs; cystic; cysts; damage; data; database; davinci; day surgery; days; death; december; decision; decrease; decubitus; deep; defect; definitive; degree; delay; delayed; delta; demanding; demographics; department; description; design; detailed; details; detection; developing; development; device; dfs; diabetes; diagnosis; diameter; diaphragmatic; diastasis; diet; differences; different; different patients; different surgical; differential; differentiated; difficult; difficulties; diffuse; digestive; dilatation; dimensional; dindo; direct; discharged; discomfort; discussion; disease; disorders; dissected; dissection; distance; distant; diverticulitis; diverticulum; division; docking; dor; double; drainage; dry; dss; duct; duodenal; duodenum; duration; dye; dysphagia; dysplasia; eaes; earlier; early; easier; easy; edges; education; effective; effectiveness; effects; efficacy; efficiency; elderly patients; elective laparoscopic; elective surgery; emergency surgery; emergent; endocrine; endogia; endometriosis; endoscopic approach; endoscopic resection; endoscopic surgery; endoscopic treatment; endoscopy; energy; enhanced; enterotomy; entire; entity; enucleation; environment; epigastric; episodes; equal; ercp; ergonomics; error; esd; esg; esophageal; esophageal cancer; esophageal surgery; esophagectomy; esophagitis; esophagogastric; esophagus; essential; established; estimated; etc; evaluation; events; evidence; ewl; exact; examination; excellent; excessive; excision; existing; expected; experience; experimental; expert; exploratory; exposure; extended; extensive; extent; external; extraction; facilitate; factors; failure; fascia; fashion; faster; fat; favorable; feasibility; feasible; features; february; fecal; feedback; feeding; female patient; females; fever; fibrin; fibrosis; field; figure; final; findings; fistula; fixation; flank; flap; flexible; flexure; flow; fluid; fluorescence; focused; follow; following; force; forceps; foreign; france; free; frequency; frequent; function; functional results; fundoplication; fundus; gallbladder; gastric; gastric bypass; gastric cancer; gastric resection; gastric sleeve; gastric surgery; gastric wall; gastroduodenal; gastroenterological surgery; gastroenterology; gastroesophageal; gastrointestinal; gastrointestinal surgery; gastrostomy; gaze; gc patients; gender; general surgery; gerd; gerd patients; germany; giant; gist; gland; glue; goal; gold; good; good results; grade; grasping; greater; green; groin; group; group b; growth; guidance; guidelines; hand; handling; hba1c; hcc; head; healing; health; help; helpful; hemicolectomy; hemorrhage; hemostasis; hepatectomy; hepatic; hepatic surgery; hepatobiliary surgery; hepatocellular; hernia; hernia patients; hernia repair; hernia surgery; herniation; hiatal; hiatal hernia; hiatus; high; higher; hilum; histological; histology; histopathological; history; home; hospital; hospital stay; hospitalization; hsi; human; hybrid; hypertension; hysterectomy; iatrogenic; icg; icg fluorescence; identification; ihd; iii; ileocolic; ileostomy; ileus; iliac; image; imaging; immediate; impact; implantation; implementation; important; improved; improvement; incarcerated; incidence; incidents; incision laparoscopic; incisional; incisional hernia; include; incontinence; increase; independent; index; indications; individual; indocyanine; infection; inferior; inflammation; inflammatory; influence; information; infrared; inguinal; inguinal hernia; initial; injuries; injury; insertion; inside; institute; institution; instruments; insufflation; insulin; intact; intake; intensity; interaction; interest; internal; international; intervention; intestinal; intraabdominal; intracorporeal; intrahepatic; intraoperative; intraoperative laparoscopic; intrathoracic; intravenous; introduction; intussusception; invasion; invasive approach; invasive surgery; invasive surgical; invasive technique; invasive treatment; investigations; involved; involvement; ipom; ischemic; isolated; italy; january; japan; jejunal; jejunostomy; jejunum; july; june; key; kidney; kind; knot; knowledge; known; laboratory; lack; lagb; laparoscopic abdominal; laparoscopic adrenalectomy; laparoscopic anastomosis; laparoscopic anterior; laparoscopic appendicectomies; laparoscopic approach; laparoscopic cases; laparoscopic cholecystectomy; laparoscopic colectomy; laparoscopic colorectal; laparoscopic distal; laparoscopic duodenojejunostomy; laparoscopic experience; laparoscopic exploration; laparoscopic gastrectomy; laparoscopic gastric; laparoscopic group; laparoscopic hartmann; laparoscopic heller; laparoscopic hernia; laparoscopic inguinal; laparoscopic instruments; laparoscopic intervention; laparoscopic liver; laparoscopic low; laparoscopic lymph; laparoscopic management; laparoscopic mesh; laparoscopic nissen; laparoscopic operation; laparoscopic performance; laparoscopic procedure; laparoscopic proximal; laparoscopic repair; laparoscopic resection; laparoscopic reversal; laparoscopic right; laparoscopic segmental; laparoscopic single; laparoscopic skills; laparoscopic sleeve; laparoscopic splenectomy; laparoscopic surgery; laparoscopic suturing; laparoscopic system; laparoscopic tasks; laparoscopic technique; laparoscopic total; laparoscopic training; laparoscopic treatment; laparoscopic wedge; laparoscopy; laparotomy; larc patients; large; lateral; lavage; layer; lcbde; leading; leak; leakage; learning; left; left gastric; leiomyoma; length; lesion; lesser; level; life; ligament; ligation; light; like; limb; limitations; limited; limits; line; linear; liquid; literature; little; liver resection; liver surgery; llr; lobe; local; localization; location; long; longer; loop; loss; lower; lpnd; lsg; lspdp; lumbar; lumen; lung; lymph; lymph node; lymphadenectomy; lymphatic; machine; magnetic; main; main group; maintaining; major; major surgery; majority; making; male patients; males; malignant; management; maneuver; manipulation; manner; manometry; manual; mapping; march; margin; marked; markers; mass; massive; material; maximum; mean; mean age; mean hospital; mean operative; mean time; measurement; measures; mechanism; median; mediastinal; medical; medical treatment; medicine; medium; mesenteric; mesh; meshes; mesocolic; mesocolon; mesorectal; metabolic; metabolic surgery; metastasis; methods; middle; midline; migration; minilaparotomy; minimal; mmhg; mobilization; modalities; model; moderate; modified; monitoring; months; months postoperative; morbidity; morgagni; mortality; motility; motion; movements; mri; multidisciplinary; multimodal; multiple; multivariate; muscle; myotomy; n =; narrow; national; natural; nausea; navigation; near; necessary; neck; necrosectomy; necrosis; need; needle; needlescopic; negative; neoadjuvant; neoplasia; neoplasm; nerve; neuroendocrine; new; new approach; new surgical; nir; node; node dissection; nodule; nomogram; non; noncompliance; normal; novel; november; ntnm; number; obese patients; obesity; objective; observation; observed; obstruction; october; odds; old; old male; old patient; old woman; omentum; oncological; oncological results; oncological surgery; oncology; onset; open approach; open surgery; opening; operating; operation; operation patient; operative pain; operative procedure; operative time; opportunity; optimal; option; oral; order; organs; orifice; origin; outcomes; outside; overall; overlap; ovesco; p =; pain; palpable; pancreas; pancreatectomy; pancreatic; pancreatic surgery; pancreatitis; paraesophageal; parameters; parastomal; parathyroid; parenchyma; partial; participants; particular; passage; past; pathological; pathologies; pathology; pathway; patient age; patient characteristics; patient demographics; patient outcomes; patient safety; patient underwent; patients; patients anatomy; pattern; pedicle; pelvic; pelvic laparoscopic; peptic; percentage; percutaneous; perforated; perforation; perform; performance; performing; perfusion; period; peritoneal; peritonitis; persistent; petersen; phase; pheochromocytoma; physical; pigs; placement; plane; planned; planning; plasma; platform; pleural; pneumonia; pneumoperitoneum; pod; point; polyp; polypropylene; poor; popf; population; porcine; port; port surgery; portal; position; positioning; positive; possibility; possible; post operative; posterior; postoperative; postoperative complications; postoperative course; postoperative day; postoperative hospital; postoperative morbidity; postoperative outcomes; postoperative patient; postoperative period; postoperative recovery; postoperative results; postoperative stay; potential; pouch; practice; precise; precision; predictive; preferred; preliminary results; preoperative; preperitoneal; presence; present; present study; presentation; preserving; pressure; prevalence; prevention; previous; previous laparoscopic; previous surgery; primary; principles; prior; problems; procedure; process; prognostic; program; progressive; project; promising; prone; propensity; proper; prophylactic; prospective; prosthesis; protein; protocol; proton; proximal; pseudo; pull; pulmonary; puncture; purpose; qol; quadrant; quality; quantitative; questionnaire; radical; radical surgery; radiological; randomized; range; rare; rate; ray; real; reality; reasons; recent; reconstruction; records; recovery; rectal cancer; rectal resection; recti; rectum; recurrence; redo; reduced; reduction; reflux surgery; refractory; regain; regard; region; regional; registry; regression; regular; regurgitation; related; relationship; release; relevant; reliability; reliable; remains; remnant; removal; repeat; report; reported; reporting; reproducible; research; resected; resection group; resection rate; resection surgery; resections; residents; resonance; respiratory; response; results; retrieved; retrograde; retromuscular; retroperitoneal; retrospective; retrospective study; return; reversal; review; revision surgery; revisional; rgc patients; right colon; risk; risk patients; robotic approach; robotic group; robotic rectal; robotic surgery; robotic surgical; robotic system; role; romania; room; root; route; routine; roux; running; rupture; rygb; sac; safe; safe approach; safe laparoscopic; safe procedure; safe technique; safety; saline; satisfaction; satisfactory; scale; scan; scar; scenario; scheduled; score; screening; second; secondary; sectionectomy; segment; segmentectomy; selection; self; sensitivity; sentinel; separation; september; series; seroma; service; set; setting; severe; severity; sex; shaped; sheath; short; shorter; shows; sided; sigmoid; sigmoidectomy; signal; significant; signs; silc; sils; similar; simple; simulation; singapore; single; site; size; skin; sleeve gastrectomy; sln; small; smoking patients; software; solid; solution; space; special; specific; specimen; sphincter; spleen; splenic; splenomegaly; spread; stable; stable patients; staff; stage; staging; standard; standard laparoscopic; standard surgical; standardization; standardized; stapler; stapling; starting; statistical; status; stay; stenosis; stent; step; stitches; stomach; stones; strasbourg; strategy; stress; strong; structures; students; studies; study; study group; study period; stump; subcostal; submucosal; subsequent; subtotal; successful; successful laparoscopic; sufficient; suggestive; suitable; superior; supine; supply; support; surface; surgeons; surgeries; surgery approach; surgery department; surgery group; surgery patients; surgery results; surgery service; surgery training; surgical; surgical approach; surgical complications; surgical department; surgical emergency; surgical excision; surgical experience; surgical field; surgical intervention; surgical management; surgical margins; surgical option; surgical outcomes; surgical patients; surgical procedure; surgical repair; surgical resection; surgical results; surgical site; surgical system; surgical team; surgical technique; surgical time; surgical training; surgical treatment; surveillance; survey; survival; suspicion; suture; suturing; switch; symptomatic; symptomatic patients; symptoms; syndrome; system; systematic; tamis; tapp; target; tasks; tatme; team; technical; technique; technologies; technology; temperature; tendency; tension; term; term results; terminal; testing; tests; thanks; theatre; therapeutic; therapy; thickness; thoracic; thoracic surgery; thoracoscopic; thoracoscopic surgery; thorough; thread; thyroid; thyroid surgery; time; tissue; tnm; tolerance; tomography; tool; total gastrectomy; total patients; toupet; tract; traditional; traditional laparoscopic; trainees; trainer; training; transabdominal; transanal; transection; transfusion; transverse; trauma; traumatic; treatment; treatment results; tree; trial; triangle; trocars; trunk; tube; tumor; tumor size; tumours; type; ulcer; ultrasonography; ultrasound; umbilical; unclear; uncommon; undergone; underlying; understanding; underwent; underwent laparoscopic; uneventful; unit; united; univariate; university; unknown; upper; ureter; urgent; urgent surgery; urinary; use; useful; usefulness; users; usual; uterine; utility; vaginal; validation; validity; value; variables; vascular; vascularization; vats; vein; ventral; verge; vertical; vessels; video; view; vinci; virtual; visceral; visceral surgery; visualization; vivo; volume; volvulus; vomiting; wall; way; weeks; weight; white; wide; woman; work; working; worldwide; worse; wound; wrap; y gastric; years; years old; young patients; younger cache: cord-006849-vgjz74ts.txt plain text: cord-006849-vgjz74ts.txt item: #24 of 134 id: cord-006856-b1w25ob5 author: None title: 19th Meeting of the Austrian Society of Transplantation, Transfusion, and Genetics, October 26–28, 2005 date: 2005 words: 29728 flesch: 49 summary: The average serum creatinine after 5 years is 153.56 ± 24.65 µmol/l. Cumulative graft survival after 5 years is shown by Kaplan-Meier curve: graft survival, 75.1%; patients survival, 83.9%; graft and patients survival, 67.1%. Extracorporeal photopheresis has been shown to be beneficial in acute and chronic rejection in heart transplant patients and has also been used in lung transplant recipients with acute rejection or bronchiolitis obliterans. Methods. keywords: abdominal; activation; activity; acute; addition; age; aim; alive; allogeneic; allograft; als; aml; analyse; analysis; anti; antibody; antigen; artery; ascites; assay; atg; auf; aus; autologous; average; background; bacterial; balb; basis; bei; biopsy; bleeding; blockade; blood; bmt; bnp; bone; bos; bronchial; c4d; c57bl/6; cancer; candida; cardiac; cardiomyocytes; cases; cd25; cd3; cd4; cells; cellular; center; chimerism; cholestatic; chronic; cirrhosis; clearance; clinical; cmv; cohort; cold; collection; combination; combined; common; comparable; comparison; complete; complications; conclusions; conditioning; consecutive; continuous; contrast; control; course; creatinine; criteria; csa; csf; ctla4ig; cuff; cumulative; cyclosporine; cytotect; das; data; day; days; dcm; dcs; death; decrease; dependent; der; des; diagnosis; die; dieser; different; disease; disorders; dna; donation; donor; dose; drug; dst; dysfunction; early; ecmo; effect; eine; end; episodes; ergebnisse; established; events; everolimus; excellent; expression; extended; factor; failure; female; fibrosis; follow; following; fty720; function; fungal; für; gcm; genotype; gms; good; grade; graft; graft survival; group; growth; gruppe; gvhd; h-2; hbcab; hbig; hbv; hcc; hcv; heart; hepatitis; high; higher; hl-1; ho-1; hplc; hsct; htx; human; iii; immunosuppression; impact; implantation; important; incidence; increase; induction; infection; inflammation; inhibitor; innsbruck; institution; intra; ischemia; islet; isolated; isolation; kaplan; kidney; left; levels; like; lipocalin-2; list; liver; living; long; loss; lower; lung; lung transplantation; lymphoma; majority; male; mapk; marginal; marrow; mars; mean; median; medical; meier; meld; methods; mice; microscopy; min; mit; mixed; model; moderate; mofetil; monitoring; months; mortality; multiple; mycophenolate; myeloablative; myocardial; n =; nach; negative; neoplasms; new; nicht; non; normal; number; observation; observed; organ; outcome; overall; p =; p38; pancreas; pancreatic; pap; parameters; particular; pathogens; patient survival; patienten; patients; pbsc; pcr; period; peripheral; phosphorylation; platelet; plb; population; positive; post; postoperative; posttransplant; potential; preoperative; preservation; primary; prior; probability; procedure; progression; proliferation; prophylaxis; protein; proteinuria; protocol; ptld; pts; pulmonary; quality; range; rate; ratg; ratio; recipients; recurrence; reduced; reduction; regimen; rejection; relapse; related; remission; renal; reperfusion; report; response; results; retrospective; ric; risk; role; s1p; sample; schlussfolgerungen; score; sepsis; serum; severe; sex; short; sich; significant; similar; sirolimus; skin; slpi; small; solid; solutions; specific; srl; stable; stage; standard; stem; stent; steroids; stimulation; studiengruppe; studies; study; substantial; suffering; surgical; survival; switch; system; tacrolimus; tbi; technique; term; test; tgf; therapeutic; therapy; time; tissue; tolerance; total; transplant patients; transplantation; transplanted; treatment; trm; tumor; type; underwent; university; unrelated; urine; use; values; vascular; vegf; venous; ventricular; vitro; vivo; von; waiting; war; weeks; werden; wien; wurde; years; zellen cache: cord-006856-b1w25ob5.txt plain text: cord-006856-b1w25ob5.txt item: #25 of 134 id: cord-006870-f5w6fw6q author: None title: Abstracts Presented at the Neurocritical Care Society (NCS) 15th Annual Meeting date: 2017-09-19 words: 122395 flesch: 46 summary: The best model fit was for good outcome (modified Rankin Score 0-2 equivalents) based on % patients with WFNS 4-5 and age (R2=0.54; p<0.001). Decreasing time spent in cervical spinal immobilization could improve patient care by allowing greater access to / range-of-motion of the neck, increasing patient comfort, and decreasing skin breakdown. keywords: 95%ci; abnormal; absence; absent; absolute; academic; access; accurate; activation; activity; actual; acute; acute brain; acute care; acute ischemic; acute stroke; adc; additional; adjusted; adjustment; administration; admission; adr; adult patients; adults; advanced; adverse; aed; aeds; agents; aggressive; aim; air; airway; ais; algorithm; altered; alternative; american; amyloid; analysis; andexanet; anesthetic; aneurysm; angiogram; angiography; animals; anoxic; anterior; anti; antibiotics; anticoagulation; antiepileptic; antihypertensive; antimicrobial; antiplatelet; antithrombotic; apache; apixaban; apnea; application; approach; appropriate; april; area; arrest; arrest patients; arrival; arterial; artery; articles; asah; asah patients; aspirin; assessment; associated; association; auc; autoimmune; autoregulation; available; average; background; basal; baseline; basic; basilar; bedside; beneficial; benefit; best; betrixaban; better; bilateral; bleeding; blinded; blood; body; bolus; brain; brain death; brain injury; brainstem; brv; bundle; burden; burst; bypass; calculated; cardiac; cardiomyopathy; cardiovascular; care patients; care unit; carotid; case; category; catheter; causes; cauti; cbf; ceeg; cells; center; central; cerebellar; cerebral; cerebral edema; cervical; challenging; change; characteristics; characterized; chart; chest; chloride; chronic; circulation; cistern; classified; clearance; clinical; clinical care; clinical outcomes; clinicians; clot; cn-105; cns; coagulopathy; code; cognitive; cohort; cohort study; collaboration; collection; coma; comatose patients; comfort; common; communication; comorbidities; complete; complex; compliance; complicated; complications; component; comprehensive; concentrations; concerns; condition; confidence; confirmed; confounders; confusion; connectivity; consciousness; consecutive patients; consent; consistent; continued; continuous; contrast; control; conventional; conversion; convulsive; cooling; correlation; cortical; cost; course; cox; cpp; cpr; craniectomy; creatinine; criteria; cross; csf; cta; cultures; current; curve; cvst; daily; data; database; date; days; dbd; dci; death; december; decision; decline; decompressive; decrease; dedicated; deep; deficits; degree; delay; delirium; delivery; demographics; department; design; desmopressin; detection; deterioration; determined; developed; development; device; diabetes; diagnosis; diameter; difference; difficult; diffuse; diffusion; direct; disability; discharge; discontinuation; disease; diversion; donation; door; doppler; dose; dosing; drainage; drug; dsa; duration; dysfunction; eaca; earlier; early; ecmo; edema; education; eeg; eegs; effect; effective; effectiveness; efficacy; ekg; elderly patients; elective; electrographic; electronic; elevated; embolism; embolization; emergency; emergent; encephalitis; encephalopathy; endovascular; engagement; enls; enrollment; enteral; epilepsy; epilepticus; epileptiform; established; estimates; etiology; evaluation; evd; events; evidence; exact; exam; examination; expansion; experience; expert; expertise; exposure; extensive; external; extubation; eye; facility; factors; failed; failure; false; families; family; favorable; feasibility; features; female; fever; field; final; findings; fisher; flow; fluid; focal; following; free; frequency; frequent; frontal; functional; future; fxa; ganglia; gcs; gender; generalized; glasgow; global; glucose; goal; good; gos; grade; greater; group; guidelines; half; head; headache; health; healthcare; heart; hematoma; hemicraniectomy; hemisphere; hemodynamic; hemorrhage; hemorrhage patients; herniation; hess; higher; highest; history; home; hospice; hospital; hospital discharge; hospital mortality; hospitalization; hours; hours post; hts; human; hunt; hydrocephalus; hypertension; hypertonic; hypothermia; hypothesis; hypoxic; icd-9; ich patients; icp; icu; identification; identified; iic; iii; ill; illness; imaging; immediate; impact; impaired; implementation; important; improved; improvement; incidence; inclusion; increase; independent; index; individual; induced; infarction; infections; inflammation; inflammatory; influence; information; infusion; inhibitors; initial; initiation; injured; injuries; injury; injury patients; inpatient; inr; insertion; instability; institution; insurance; intensive; intensive care; internal; international; intervention; intracerebral; intracranial; intracranial hemorrhage; intraparenchymal; intravenous; intraventricular; intubated; invasive; involved; involvement; iph; iqr; ischemic; ischemic stroke; isolated; ivh; january; jugular; july; june; ketamine; knowledge; known; laboratory; lack; lactate; large; lead; leading; left; length; lesions; level; levetiracetam; life; likelihood; likely; limited; linear; literature; little; lobe; location; logistic; longer; los; loss; lower; lumbar; lung; magnetic; major; majority; making; malignant; management; map; march; markers; mass; matter; maximum; mca; mcg; mean; mean age; measured; measurement; mechanical; mechanism; median; medical; medical patients; medications; medicine; meeting; members; meningitis; mental; metabolic; method; metrics; midazolam; middle; midline; mild; milrinone; minutes; mmhg; model; moderate; modified; monitoring; months; morbidity; mortality; motor; mri; mri brain; mrs; multicenter; multidisciplinary; multimodal; multiple; multivariable; myoclonus; n=3; national; nccu; ncse; necessary; need; negative; nerve; network; neurocritical; neurocritical care; neuroicu; neuroimaging; neurological; neurological patients; neurology; neurosciences; neurostimulant; neurosurgical; new; nicu; nihss; nirs; noac; non; normal; novel; npi; nri; number; nurses; nursing; obese patients; obesity; objective; observational; observed; occipital; occlusion; occurrence; odds; old; ongoing; onsd; onset; operative; optimal; oral; order; organ; osmotherapy; outcome; outcome patients; outpatient; overall; oxygen; oxygenation; p<0.001; pa patients; pain; painful; palliative; pao2; parameters; participants; participation; past; pathology; pathway; patient days; patient population; patients; patterns; pbto2; pcc; peak; percent; performance; perfusion; perihematomal; period; periodic; peripheral; pet; pharmacokinetic; phase; phe; phenytoin; physical; physicians; physiologic; pilot; placebo; placement; plan; plasma; platelet; pneumonia; point; poor; poor outcome; population; positive; possible; post; posterior; postoperative; potential; practice; practitioners; predictive; predictors; presence; present; presentation; pressure; prevalence; previous; primary; prior; probability; procedure; process; prognosis; prognostication; program; progressive; project; prolonged; prophylaxis; propofol; proportion; prospective; protein; protocol; providers; pulmonary; puncture; pupil; pupillary; purpose; qeeg; quality; quantitative; radiographic; randomized; range; rankin; rapid; rare; rate; recanalization; recent; receptor; recipients; recommendations; records; recovery; recurrent; reduced; reduction; reference; reflex; refractory; regimen; regional; regions; registry; regression; rehabilitation; reintubation; related; relationship; relative; removal; renal; repeat; report; research; residents; resolution; resonance; resources; respiratory; respondents; response; results; resuscitation; retrospective; reversal; reversible; review; right; risk; risk patients; rivaroxaban; role; rounds; routine; rrsa; safety; sah patients; saline; sample; satisfaction; sbd; scale; scan; score; screening; sdh; secondary; sedation; sedative; seizures; selection; self; sensitivity; sepsis; serial; series; serum; services; setting; severe; severity; sex; shift; shock; shorter; sich; sided; signal; significant; signs; similar; single; sinus; site; size; small; social; society; sodium; sofa; specific; specificity; spinal; spine; spontaneous; spot; srse; stable; staff; standard; standardized; state; statistical; status; status epilepticus; stay; steroids; stimulation; strategies; strategy; stroke care; stroke patients; strokes; studies; study; subarachnoid; subarachnoid hemorrhage; subcortical; subdural; subjects; subsequent; successful; super; support; suppression; surgery; surgical; survey; survival; survivors; suspicion; sympathetic; symptomatic; symptoms; syndrome; system; systemic; systolic; target; tbi patients; tcd; team; technique; temperature; temporal; tertiary; test; testing; therapeutic; therapies; therapy; threatening; thrombectomy; thrombosis; time; timely; timing; tissue; tlas; tomography; tool; total; tpa; tracheostomy; tract; training; transfer; transfer patients; transition; trauma patients; traumatic; traumatic brain; treatment; trend; triage; trial; ttm; tube; type; ultrasound; unclear; underlying; understanding; underwent; unique; unit; univariate; university; unknown; unruptured; urgent; urinary; urine; use; useful; utilization; validation; valproate; values; valve; vancomycin; variability; variables; vasopressor; vasospasm; venous; ventilation; ventricular; verapamil; versus; vessel; visual; volume; vps patients; vte; vwe; warfarin; weakness; weaning; weeks; weighted; white; withdrawal; woman; workshop; workup; worsening; years; younger; younger patients cache: cord-006870-f5w6fw6q.txt plain text: cord-006870-f5w6fw6q.txt item: #26 of 134 id: cord-006876-v2m5l5wz author: None title: Neurocritical Care Society 14(th) Annual Meeting date: 2016-08-11 words: 59827 flesch: 46 summary: However, the trend was not uniform -48% patients had no correlation between rSO2 and CPP, 29% showed a positive correlation and 23% showed a negative correlation. Major reasons for satisfaction included: physician response to emergencies, physician -nurse communication, and patient outcome. keywords: 95%ci; academic; accuracy; activity; acute; additional; adjusted; administration; admission; adult patients; adults; adverse; aeeg; agents; aggressive; aim; ais; ais patients; analysis; aneurysmal; anticoagulation; approach; apps; april; areas; arrest; arrest patients; arterial; artery; asah; asah patients; assessment; associated; association; autoimmune; available; average; awareness; baclofen; baseline; bedside; benefit; best; better; bilateral; bleeding; blood; brain; brain death; brain injury; burden; burst; calculated; cardiac; care; care patients; care unit; case; catheter; causes; cauti; cbz; cci; ceeg; center; central; cerebral; cfi; changes; characteristics; chart; children; chronic; circulation; clearance; clevidipine; clinical; clinicians; cns; cognitive; cohort; coma; comatose; combined; common; communication; complete; complex; complications; conditions; consecutive; consecutive patients; consistent; continuous; contrast; control; cooling; correlation; course; cpp; craniotomy; crcl; criteria; csf; cumulative; current; curve; daily; data; database; days; dci; death; december; decision; decreased; delayed; delirium; delta; demographics; department; developed; development; device; diagnosis; difference; direct; disability; discharge; discussion; disease; disposition; dose; dosing; drains; drug; duration; dvt; dysfunction; early; ecmo; edema; eeg; effect; effective; efficacy; electronic; elevated; elevations; emergency; endovascular; enteral; epilepticus; episodes; etiology; evaluated; evaluation; evd; events; evidence; exam; examination; existing; expansion; experience; extensive; external; eye; factor; failure; families; family; feasible; features; female; fever; findings; fisher; flow; following; functional; functional outcome; future; gcs; gender; generalized; glasgow; global; glucose; goal; good; good outcome; gos; grade; grade patients; greater; group; guidelines; head; headache; health; healthcare; help; hematoma; hemodynamic; hemorrhage; heparin; hess; high; higher; history; home; hospital; hospital care; hospital mortality; hospitalization; hours; hunt; hydrocephalus; hypertension; hypothermia; iabp; ich; ich patients; icp; icu; ill; imaging; immediate; impact; implementation; important; improved; improvement; incidence; inclusion; increase; independent; individual; infection; information; infusion; initial; initiation; injured; injuries; injury; inr; institutional; intensive; intensive care; interest; interval; intervention; intracerebral; intracranial; intracranial hemorrhage; intravenous; intraventricular; invasive; investigation; iqr; ischemia; ivh; january; july; ketamine; lactate; large; leading; left; length; levels; levetiracetam; life; likely; limited; literature; location; logistic; long; longer; loss; lower; major; majority; male; malignant; management; mannitol; march; mean; mean age; measured; measurements; mechanical; mechanism; median; medical; medications; members; metabolic; methods; middle; mild; minutes; mmhg; mobility; mobilization; model; moderate; modified; monitoring; months; morbidity; mortality; motor; mri; mrs; multicenter; multidisciplinary; multimodal; multiple; multivariate; nccu; ncse; necessary; need; negative; neurocritical; neurocritical care; neuroimaging; neurointensivists; neurological; neurological outcome; neurology; neuromonitoring; neurosurgery; neurosurgical; new; nicardipine; nicu; nihss; nimodipine; non; normal; number; nurses; nursing; nutrition; obese; obese patients; objective; observational; observed; odds; old; ongoing; onsd; onset; operative; optimal; oral; order; organ; outcome; overall; oxygen; oxygenation; p<0.001; pain; palliative; parameters; patients; patterns; pbto2; pcc; perfusion; period; phe; physicians; placement; plasma; platelet; poor; poor outcome; population; positive; post; posterior; potential; practice; predictive; predictors; presence; present; presentation; pressure; prevalence; primary; primary outcome; prior; procedure; prognosis; prognostication; program; prolonged; prophylactic; prophylaxis; prospective; protocol; providers; ptt; public; purpose; qeeg; quality; randomized; range; rare; rate; real; recanalization; recent; records; recovery; reduced; reduction; refractory; regimen; regression; related; repeat; report; research; resection; residents; respiratory; response; results; retrospective; retrospective study; reversal; review; right; risk; rosc; rounds; rso2; safety; sage-547; sah; sah patients; sample; satisfaction; sbp; scale; scans; score; sdh; secondary; sedation; seizures; sensitivity; september; series; serum; setting; severe; severity; shift; significant; similar; single; size; small; specific; specificity; spontaneous; spot; srse; srt; staffing; standard; status; stay; strategies; stroke; studies; study; study patients; subarachnoid; subarachnoid hemorrhage; subdural; subjects; subsequent; successful; super; support; suppression; surgical; survey; survival; survivors; symptomatic; symptoms; syndrome; system; systemic; systolic; target; tbi; tbi patients; tcd; team; temperature; term; tertiary; test; testing; therapeutic; therapy; thrombosis; time; timing; tissue; tool; total; tpa; training; traumatic; traumatic brain; treated; treatment; trend; trial; ttm; tube; tumor; type; understanding; underweight; underwent; unique; unit; university; urinary; usa; use; utilization; values; variability; variables; vasospasm; venous; ventilation; versus; video; volume; warfarin; waves; weight; wlst; woman; worse; years; young cache: cord-006876-v2m5l5wz.txt plain text: cord-006876-v2m5l5wz.txt item: #27 of 134 id: cord-006880-9dgmdtj8 author: None title: Neurocritical Care Society 10th Annual Meeting: October 4 - 7, 2012 Sheraton Denver Downtown Hotel Denver, Colorado date: 2012-09-19 words: 82474 flesch: 47 summary: Included patients were 55.5 ±15.2 years old with female preponderance (65.5%, (76/116)). Admission NIHSS was 11 for ICU patients and 9 for SU patients (NS). keywords: abnormal; abnormalities; academic; accuracy; accurate; acidosis; activity; acute; acute brain; adc; additional; adjusted; administration; admission; adult patients; adults; advanced; affected; agents; aggressive; airway; ais; algorithm; amnesia; analysis; aneurysm; angiogram; angiography; animals; anterior; antibiotics; anticoagulation; aoc; apache; apical; apnea; approach; appropriate; area; arousal; arrest; arrest patients; arrival; arterial; artery; asah patients; assessment; association; available; average; bal; basal; baseline; basilar; bed; benefit; beta; better; bicarbonate; bilateral; blast; bleeding; blinded; blood; body; brain; brain death; brain injury; brainstem; burden; burst; calculated; cardiac; care; care patients; care unit; case; catheter; causes; cbf; ceeg; cell; center; central; cerebral; cerebral blood; challenging; changes; characteristics; chart; children; chronic; circulation; civ; clinical; clinical data; clinical outcome; clinicians; clipping; clot; cns; code; cognitive; cohort; cohort study; collected; coma; comatose patients; common; comparable; comparison; complete; complex; complications; comprehensive; concentration; condition; confirmed; consciousness; consecutive patients; consistent; continuous; control; correlate; correlation; cost; count; course; cpc; cpp; criteria; critically; csf; ctp; cultures; current; curve; dabigatran; daily; data; database; days; dci; death; december; decision; decompressive; decreased; deep; deficits; degree; delayed; demographics; department; detection; deterioration; development; device; diabetes; diagnosis; differences; different; difficult; diffuse; diffusion; direct; disability; discharge; disease; distance; dnr; dose; drainage; drug; dsa; duration; dwi; dysfunction; early; edema; education; eeg; effect; effective; efficacy; efforts; elevated; emergency; employment; encephalopathy; endovascular; epilepticus; epileptiform; episodes; established; ethnicity; etiology; evaluation; events; evidence; exam; examination; expansion; experience; exposure; external; facility; factors; failure; fall; family; favorable; female; fever; ffp; fibrillation; financial; findings; fisher; flow; fluid; following; free; frequency; frequent; frontal; functional; functional outcome; future; gcs; gender; general; generalized; glasgow; glucose; goal; good; good outcome; gos; grade; greater; group; guidelines; head; headache; health; healthcare; heart; help; hematoma; hemodynamic; hemorrhage; heparin; hess; higher; history; home; hospital; hospital mortality; hospitalization; hours; hts; hunt; hydrocephalus; hyperoxia; hypertension; hypertonic; hyponatremia; hypothermia; hypothesized; icf; ich; icp; icu; icu admission; icu patients; icus; ill; illness; imaging; immune; impact; implementation; important; improved; improvement; incidence; increased; independent; index; individual; induced; induction; infarct; infection; influence; information; infusion; initial; initiation; injured; injury; injury patients; inr; institution; intensive; intensive care; interval; intervention; intracerebral; intracranial; intraoperative; intravenous; intraventricular; intubated; intubation; invasive; iph; iqr; ischemic; ischemic stroke; isolated; ivh; january; knowledge; known; laboratory; larger; lead; leading; left; length; lesions; levels; life; likelihood; likely; limited; literature; loc; location; logistic; longer; los; loss; lower; lpr; lung; magnesium; major; majority; male; management; mannitol; map; mass; maximum; mca; mdz; mean; mean age; measured; measurements; mechanical; mechanism; median; medical; medications; medicine; members; meningitis; metabolic; method; microdialysate; middle; mild; minutes; mmhg; model; moderate; modified; monitoring; months; morbidity; mortality; motor; mri; mrs; mrs-9q; mstbi; multimodal; multiple; multivariate; myocardial; national; nccu; neck; need; negative; nerve; neurocritical; neurocritical care; neurointensivists; neurological; neurology; neuronal; neurosurgical; new; nicardipine; nicu; nihss; nirs; non; normal; novel; nps; number; nurses; nursing; oaa; objective; observational; observed; occlusion; occurrence; odds; old; onset; optimal; order; organ; outcome; outcome data; outcome scale; outside; overall; oxygen; p<0.0001; p<0.05; parameters; past; patient outcome; patients; patterns; pcc; pct; peak; pediatric; pediatric patients; percentage; performance; perfusion; period; phase; phenytoin; physicians; physiologic; placement; plasma; pneumonia; point; poor; poor outcome; population; positive; post; posterior; potential; practice; predictive; predictors; presence; present; presentation; pressure; previous; primary; prior; procalcitonin; procedures; process; prognosis; prognostication; program; project; prolonged; prophylaxis; prospective; protocol; pta; pulmonary; pulse; purpose; qol; quality; quantitative; radiographic; range; rankin; rapid; rare; rate; rbc; recent; records; recovery; reduced; reduction; refractory; regression; related; relationship; relative; renal; repeat; report; required; research; residents; resolution; respiratory; respondents; response; results; resuscitation; retrospective; reversal; review; rfviia; rhythm; right; risk; risk patients; role; rosc; routine; rupture; safety; sah; sah patients; saline; sample; sbp; scale; scan; score; screening; sdh; secondary; sedation; seizures; sensitive; sensitivity; sepsis; series; serum; setting; severe; severity; shift; significant; signs; similar; single; size; small; sna; sodium; software; specific; specificity; spinal; spine; spontaneous; stabilization; stable; staff; standard; state; statin; statistical; status; stay; stroke patients; strokes; studies; study; study patients; subacute; subarachnoid; subarachnoid hemorrhage; subdural; subjects; subsequent; successful; support; suppression; surgery; surgical; survey; survival; survivors; symptoms; syndrome; system; systemic; systolic; target; tbi; tbi patients; tcd; team; technique; temperature; term; tertiary; test; testing; therapeutic; therapies; therapy; time; tissue; tool; total; tpa; tracheostomy; training; transcranial; transfer; transfusion; traumatic; traumatic brain; treating; treatment; trend; trial; type; ultrasound; unclear; underlying; underwent; unit; united; univariate; university; unknown; upper; use; useful; users; utility; utilization; validated; values; vap; variability; variables; variation; vasoconstriction; vasospasm; ventilation; vessel; volume; vomiting; vs.; warfarin; water; wbc; weeks; white; wlst; women; work; worse; worsening; years cache: cord-006880-9dgmdtj8.txt plain text: cord-006880-9dgmdtj8.txt item: #28 of 134 id: cord-007064-nepgttxf author: Chemaly, Roy F title: A Phase II, Randomized, Double-blind, Placebo-Controlled Trial of Presatovir for the Treatment of Respiratory Syncytial Virus Upper Respiratory Tract Infection in Hematopoietic-Cell Transplant Recipients date: 2019-12-03 words: 5041 flesch: 37 summary: Patients with new or worsening respiratory symptoms for ≤7 days, who had been diagnosed with an RSV infection of the upper respiratory tract for ≤6 days, and who were without new abnormalities on a chest X-ray obtained <48 hours from the start of study treatment were eligible to participate. Patients with a specified, documented respiratory virus coinfection within 7 days from the start of study treatment or with another significant respiratory or systemic infection were excluded. keywords: adult; aerosolized; analysis; average; baseline; cell; change; clinical; conduct; copies; coprimary; current; current study; day; days; efficacy; endpoint; fees; gilead; gilead sciences; grants; hct; hematopoietic; inc; infection; institution; load; log; lower; lrtc; lrti; lymphopenia; merck; methods; patients; personal; placebo; presatovir; randomized; recipients; relative; research; respiratory; results; ribavirin; rsv; safety; sciences; sciences inc; secondary; shire; stem; studies; study; supplementary; syncytial; table; time; tract; transplant; treatment; trial; upper; use; viral; virus cache: cord-007064-nepgttxf.txt plain text: cord-007064-nepgttxf.txt item: #29 of 134 id: cord-007178-h0ordzm9 author: Felts, Paul A. title: Inflammation and primary demyelination induced by the intraspinal injection of lipopolysaccharide date: 2005-05-04 words: 9522 flesch: 41 summary: LPS injection markedly increased such labelling, and by 4 h after LPS injection labelling had increased in both the number of labelled vessels and the apparent intensity of labelling (Fig. 6C) . At 14 days after LPS injection, the axons in lesions from dexamethasonetreated animals tended to be surrounded by whorls of myelin debris, whereas naked demyelinated axons, or demyelinated axons associated with cell processes, were particularly common in LPS lesions from saline-treated animals. keywords: activation; acute; adjacent; animals; antibody; appearance; area; arrows; astrocytes; axons; blood; brain; cells; cns; column; cord; damage; days; debris; deep; demyelinated; demyelination; dexamethasone; dilution; dorsal; dorsal funiculus; early; ed1; electron; endotoxin; et al; examined; expression; extracellular; factor; fig; funiculus; gfap; grey; icam-1; il-1b; induced; inflammation; inflammatory; injection; inos; labelling; large; left; lesion; light; like; lipopolysaccharide; loss; lps; lps injection; lymphocytes; macrophages; matter; microglia; microscopy; multiple; n =; normal; number; observed; oligodendrocytes; parenchyma; pmns; positive; positive cells; present; primary; processes; prominent; rat; receptor; region; response; result; saline; schwann; sclerosis; sections; sigma; similar; site; small; spinal; studies; substantial; time; tissue; tlr4; treatment; vessels; virus; white cache: cord-007178-h0ordzm9.txt plain text: cord-007178-h0ordzm9.txt item: #30 of 134 id: cord-007288-lzxi6q1p author: Pazin, George J. title: Leukocyte Interferon for Treating First Episodes of Genital Herpes in Women date: 1987-12-17 words: 4205 flesch: 49 summary: A therapeutic effect of human leukocyte interferon on initial genital herpes was documented, but the clinical usefulness of interferon treatment of genital herpes is limited at this time. The effects of interferon treatment on the initial episode of genital herpes are shown in figures 2-5. keywords: analysis; counts; cultures; daily; days; difference; disease; duration; effect; enrollment; episodes; figure; follow; frequency; genital; group; healing; herpes; hsv; human; infection; initial; interferon; lesions; leukocyte; levels; mean; pain; patients; period; placebo; primary; recurrences; shedding; significant; simplex; specimens; study; subjects; table; therapy; time; titers; total; treatment; type; virus; year cache: cord-007288-lzxi6q1p.txt plain text: cord-007288-lzxi6q1p.txt item: #31 of 134 id: cord-007456-acbo4zs2 author: Thomas, L.H. title: Growth of Mycoplasma bovis in organ cultures of bovine foetal trachea and comparison with Mycoplasma dispar date: 2002-11-13 words: 2800 flesch: 43 summary: key: cord-007456-acbo4zs2 authors: Thomas, L.H.; Howard, C.J.; Parsons, K.R.; Anger, H.S. title: Growth of Mycoplasma bovis in organ cultures of bovine foetal trachea and comparison with Mycoplasma dispar date: 2002-11-13 journal: Vet Microbiol DOI: 10.1016/0378-1135(87)90044-7 sha: doc_id: 7456 cord_uid: acbo4zs2 Inoculation of tracheal organ cultures from bovine foetuses with Mycoplasma bovis resulted in a loss of cellular structure of the lamina propria, followed 20–22 days later by lifting and detachment of overlying epithelium. (1969 Collier et al. ( , 1971 to investigate the effects of M. pneumoniae in organ cultures of hamster trachea, by Cherry and Taylor-Robinson (1970) to study M. mycoides var capri in chicken tracheal organ cultures, by Pijoan et al. (1972) to investigate four porcine mycoplasmas in pig tracheal organ cultures and by Thomas and Howard (1974) to study four bovine mycoplasmas in foetal calf tracheal organ cultures. keywords: activity; bovine; bovis; cells; cfu; cultures; cytopathic; day; days; dispar; effect; epithelium; experiment; howard; inoculated; inoculation; isolated; lamina; large; medium; mycoplasma; numbers; organ; organisms; propria; respiratory; sampled; thomas; tissue; tracheal cache: cord-007456-acbo4zs2.txt plain text: cord-007456-acbo4zs2.txt item: #32 of 134 id: cord-009772-pzxvicee author: GRÜNBERG, K. title: Effect of experimental rhinovirus 16 colds on airway hyperresponsiveness to histamine and interleukin‐8 in nasal lavage in asthmatic subjects in vivo date: 2006-04-27 words: 4962 flesch: 54 summary: Bronchial reactivity to histamine and bradykinin is unchanged after rhinovirus infection in normal subjects Lower airway responses to rhinovirus 39 in healthy allergic and nonallergic subjects Exacerbations of asthma in adult.s during experimental rhinovirus infection Lower airways intlammalion Jurinj; rhinovirus colds in nomia! The effects of experimental rhinovirus infection on airway responsiveness to inhaled histamine are somewhat controversial. keywords: airway; allergic; antibodies; asthma; asthmatic; atopic; baseline; blood; cells; change; chemokines; children; cold; day; days; decrease; difference; dose; effect; exacerbations; experimental; figure; group; histamine; hypersensitivity; il-8; increase; infection; inflammation; inoculation; lavage; levels; manova; mean; nasal; neutralizing; number; patients; pc20; peripheral; placebo; present; release; respiratory; response; results; rhinovirus; rise; rv16; rvi6; rvl6; score; secretions; sem; severe; significant; study; subjects; symptoms; table; viruses; vivo; washings cache: cord-009772-pzxvicee.txt plain text: cord-009772-pzxvicee.txt item: #33 of 134 id: cord-010119-t1x9gknd author: None title: Abstract Presentations from the AABB Annual Meeting San Diego, CA ctober 7‐10, 2017 date: 2017-09-04 words: 230433 flesch: 50 summary: Probability of occurrence of cannabis metabolites in blood donor samples is likely to be highly variable across donor centers and is largely dependent on blood donor demographics. OBRR, CBER, FDA Background/Case Studies: Extended molecular typing of a large number of blood donors can increase the likelihood of identifying donor red blood cells (RBCs) that match those of the recipient. keywords: -ipf; 1,2; 2,3; 48c; 68c; 7)-d; aabb; abbott; abc; ability; abnormal; abo; abo blood; absence; absent; absolute; abstract; academic; acceptable; accepted; access; account; accuracy; accurate; acid; acoustic; activated; activations; activities; actual; acute; acute blood; adamts13; additional; additional blood; additive; address; adequate; adherence; adhesion; adjusted; administration; admission; adsorption; adult; adverse; aes; affected; african; agglutination; aggregation; agreement; ahg; ahus; aid; aim; aims; ais; albumin; alert; algorithm; alinity; aliquots; alleles; allergic; alloantibodies; alloantibody; allogeneic blood; alloimmunization; allow; alpha; altered; alternative; alyx; american; amicus; amino; amotosalen; amplification; amsc; amustaline; analysis; analytical; analyzed; analyzers; anemia; annual; anova; anti; antibodies; antibody; antibody screen; antibody testing; antigen; antigen negative; antiglobulin; antisera; anwj; ap donors; apheresis; apheresis donors; apheresis platelet; apparent; application; applied; appointment; approach; appropriate; approval; april; aprp; ardp; areas; as-3; assay; assessment; associated; association; asymptomatic; at1rab; atp; audit; august; autoab; autoimmune; autologous; autologous blood; automated; automation; availability; available; average; average blood; awareness; away; b cells; babesia; baby; background; bacterial; bactx; bags; band; banks; baseline; basis; bbc; bct; beadchip; beads; bedside; benefit; best; better; bilirubin; biotin; birth; bis; bleeding; blood; blood bank; blood banking; blood cells; blood center; blood collection; blood components; blood count; blood cultures; blood donation; blood donors; blood drives; blood establishments; blood filtration; blood flow; blood fridge; blood group; blood grouping; blood inventory; blood loss; blood management; blood mononuclear; blood order; blood ordering; blood pathway; blood plasma; blood pressure; blood products; blood quality; blood recipients; blood refusal; blood safety; blood samples; blood screening; blood services; blood shortage; blood smear; blood specimens; blood supplier; blood supply; blood system; blood testing; blood therapeutics; blood transfusion; blood tubes; blood type; blood typing; blood units; blood use; blood utilization; blood volume; bmi; bmsc; bone; bottles; box; bpa; bpn; brazil; brazilian blood; breast; bryant; bthc blood; buccal; buffy; c.1154; c3d; calculated; calls; canadian blood; cancer; capable; capacity; capture; cardiac; cardiovascular; cards; care; caribbean; case studies; case study; cases; categories; category; catheter; caucasian; cause; cbc; cd341; cd36; cd38; cd4; cd47; cd62p; cd8; cell antibodies; cell collection; cell disease; cell patients; cell transfusion; cell units; cellular; cellular blood; center background; centers; central blood; centrifugation; centrifuge; certain; cerus; cfu; chain; challenge; challenging; change; characteristics; characterized; chart; chemotherapy; chen; children; china; chinese; christopher; chronic; circulation; citrate; civilian blood; class; classified; clearance; client; clinical; clinicians; clone; closed; clotting; cml; cmnc; cms; coagulation; coat; cobasv; cobe; code; cohort; cohort study; cold; collaboration; collagen; collected; collections; color; column; combination; comfort; commercial; committee; common; communication; community; community blood; comparable; comparator; comparison; compatibility; compatible blood; complement; complete blood; completion; complex; compliance; complications; comprehensive; concentrates; concentration; concern; conclusion; concordance; conditions; confidence; confirmation; confirmatory; consecutive; consistent; consumption; contact; containers; contaminated; contamination; content; continued; continuous; contrast; control; conventional; cooler; copies; cord blood; corporation; correct; correlation; corresponding; cost; count; counter; counting; countries; country; course; coverage; criteria; critical; cross; crossmatch; crucial; cruzi; cryo; cryoprecipitate; cryopreservation; cryopreserved; culture; culture results; current; current blood; cutoff; cxcr5; cytometry; d antigen; d rhd; d35; daily; damage; dara; daratumumab; data; database; date; days; days post; death; december; decision; decline; decreased; deferral; deficiency; deglycerolization; dehp; delayed; delays; delivery; demand; demographic; density; department; dependent; depletion; derived; details; detectable; detection; determination; determined; determining; developed; development; deviation; device; diagnosis; differences; different; different blood; difficult; diluted; dilution; direct; discharged; discrepancies; discrepant; discussion; disease; disease patients; disorders; distinct; distribution; dmso; dna; documentation; donations; donor anti; donor center; donor plasma; donor population; donor samples; donor testing; donor units; dose; double; dpg; drug; dtt; duffy blood; duke; duration; e.g.; early; eastern; easy; echo; edta; edta blood; educational; effect; effective; effectiveness; efficacy; efficient; effort; electronic; electronic blood; elevated; eligibility; eligible; elisa; eluate; emergencies; emergency blood; emergent; emr; encode; encoding; end; endemic; engraftment; enhanced; enhancement; enrichment; entry; environment; enzyme; epidemic; episodes; equal; equipment; equivalent; errors; erythrocytes; erytra; esd; essential; established; estimated; etc; ethnic; ethnicity; etiology; europe; evaluation; events; evidence; evs; example; excellent; exchange; exchange transfusion; exclusion; existing; exon; expectations; expected; experience; experimental; expiration; expired; exposure; expression; extended; extensive; extent; external; extracellular; extraction; facilities; facility; factors; failure; false; family; faster; fda; feasible; february; feedback; female; female donors; ferritin; fetal; fetus; fewer; ffp; fibrinogen; ficin; filter; filtration; final; finding; flow; fluid; fluorescence; focused; fold; following; forming; forms; forward; foxp3; fraction; france; free; freezing; frequencies; frequency; frequent; fresh; frozen; frozen plasma; function; functionality; future; fviii; gamma; gaps; gel; gender; gene; general; generation; genetic; genomic; genotype; genotyping; george; given; glucose; glycine; gmbh; goal; good; grade; granulocyte; greater; grifols; group b; group o; group system; groups; growth; guidance; guidelines; gvhd; haemonetics; half; haplotype; haptoglobin; harm; hba1c; hbc; hbsag; hbv; hct; hcv; hdfn; hdn; health; healthcare; heart; help; hematocrit; hematologic; hematopoietic; hemoglobin; hemolysis; hemolytic transfusion; hemorrhage; hemostatic; hepatitis; heterozygous; hev; hgb; high; high blood; higher; highest; hips; hispanic; historical blood; history; hiv; hla; homozygous; hospital; hospital background; hospital blood; hospital transfusion; hospitalization; hours; hpa; hpa-1a; hpc; hsct; htlv; human; human blood; human plasma; hybrid; hypotension; iatrogenic blood; icu; ideal; identical; identification; identity; igg; igm; ih-1000; immature; immediate; immucor; immune; immunoassay; immunogenicity; immunoglobulin; immunohematology; impact; implementation; implicated; important; improved; improvement; inactivation; incidence; incident; incompatible; increased; increment; incubated; incubation; indeterminate; index; indications; indirect; individuals; induced; infants; infected; infection; inflammation; inflammatory; influence; information; infusion; inhibitor; initial; initiation; injury; inpatient; inr; institute; institution; instructions; instrument; integrity; intended; intensity; intensive; intercept blood; interface; interference; internal; international; intervals; intervention; intravenous; introduction; intron; invasive; inventory; investigation; ipc; irl; iron; irradiated; irradiated blood; irradiation; isolated; issues; issuing; ivig; james; january; jennifer; jka; july; june; kell; key; kidd; kidney; kit; knowledge; known; label; labeling; laboratories; laboratory; laboratory results; laboratory testing; labs; lack; lactate; lancet; large; later; lead; leading; lean; learning; length; lesion; leukapheresis; leukemia; leukocyte; leukoreduced; leukoreduction; levels; ley; licensed; life; light; likely; limitations; limited; limited blood; limits; linear; lipid; liquid; liss; list; literature; little; loads; local; location; locus; logistic; long; longer; low; lower; lowest; lps; lrap; luminex; lung; lymph; lymphocytes; lymphoma; main; maintenance; majority; making; malaria; males; manner; manual; manufacturer; manufacturing; march; markers; marrow; massive transfusion; matched; matching; materials; maternal; maternal blood; maximum; mayo; mds; mean; measured; measurement; mechanisms; median; medical; medical center; medicine background; medium; meeting; members; membrane; metabolism; method; methodology; metrics; mice; michael; microbial; microscopic; microti; migration; mild; milk; minimal; minimum; minor; minutes; mirasol; missing; mitigation; mixed; mmol; mns blood; mobilization; model; molecular; molecular testing; monitoring; monoclonal; monoclonal anti; monocytes; monthly; months; morbidity; morphology; mortality; mother; mouse; msbos; mscs; mtor; mtp; mtps; multidisciplinary; multiple; multiple blood; mutation; myeloma; n51; n52; national blood; nationwide; necessary; need; negative blood; negative donors; negative rbcs; negative results; neo; neonatal; neonates; new; new blood; new method; newborn; nip; non; norcross; normal; novel; november; nucleic; nucleotide; number; numerous; nurses; nursing; objective; observation; observed; obstetric; occurrence; october; odp; old; oncology; oneg; ongoing; online; onset; operations; operative; operator; opportunities; opportunity; optia; optimal; optimization; option; oral; order; organ; organisms; organization; original; orp; ortho; otii; outcomes; outdate; outpatient; outside; overall; overload; oxygen; p<0.001; p<0.05; packed; pag3c; pain; paired; pairs; pak; pancreatitis; panel; papain; paper; parallel; parameters; parasites; partial; participants; particular; pas; past; pathogen; pathology; patient blood; patient care; patient data; patient identification; patient outcomes; patient plasma; patient population; patient rbcs; patient safety; patient samples; patients; patterns; pbm; pbmcs; pbsc; pcc; pcr; pcs; pd1; peak; pediatric; pediatric patients; peg; people; percentage; performance; period; peripheral blood; personnel; phase; phenotype; phenotype results; phlebotomy; phone; physical; physicians; pilot; placental blood; plasma; plasma anti; plasma exchange; plasma platelets; plasma samples; plasma testing; plasma transfusion; plasma units; plasma volume; plasmapheresis; platelet; platelet blood; platelet collection; platelet concentrates; platelet count; platelet donors; platelet inventory; platelet products; platelet transfusion; platelet units; plateletpheresis; platform; plerixafor; pls; plt; plt units; plts; pmn; pms; point; policy; polyclonal; polymorphism; pooled; pools; poor; population; positive; positive antibody; positive rbcs; positive results; positive samples; possibility; possible; post; post transfusion; potassium; potential; potential blood; practice; prbc; pre; precision; predictive; pregnancy; pregnant; preliminary; prenatal; preoperative; preparation; prepared; presence; present; present study; presentation; pressures; prevalence; previous; previous study; primary; primed; prior; probable; probe; problem; procedure; process; processes; processing; processor; procleix; profile; program; project; proliferation; properties; prophylactic; proportion; prospective; protein; protocol; providers; providing; province; prp; prt; pss; pts; public; pulmonary; pump; purpose; purpura; qualified blood; quality; quantitative; questionnaire; questions; random blood; randomized; range; rapid; rare; rare blood; rare donor; raritan; rate; ratios; rbc; rbc antibody; rbc antigens; rbc blood; rbc products; rbc samples; rbc storage; rbc transfusion; rbc units; rbc use; rbcs; rccs; rcf; reactive; reactive samples; reactivity; reagent; real; reasons; receipt; receiving; recent; recipients; recognized; recommendations; record; recovered; recovery; recruitment; recurrent; red blood; red cell; red cross; reduced; reduction; reference; refractoriness; refractory; regional blood; regions; regression; regular; regular blood; regulations; regulatory; rejection; rejuvenation; related; relationship; relative; release; relevant; reliable; remote blood; removal; removed; repeat; replacement; replicates; reported; reporting; reports; request; requirements; research; residents; residual; resolved; resources; respiratory; respondents; responder; response; responsible; results; resuscitation; retention; retrospective; retrospective study; return; reverse; review; revised; rflp; rh blood; rh(-; rhce; rhce*ce; rhd; rhd*diiia; rhig; rich; rise; risk; rna; robust; role; room; routine; routine blood; rrbc; rrv; rule; run; runs; sagm; saline; sample results; sampling; sandra; sanger; sanquin; saturation; savings; scale; scale blood; scd; scd patients; schedule; school; scientific; score; scott; screening; screens; sdp; second; secondary; secure; seeded; segment; selected; selection; sensitive; sensitivity; sensitization; separate; sepsis; september; septic; sequence; sequencing; series; seroconversion; serologic; serology; serum; session; set; sets; setting; severe; severity; sex; shelf; shock; short; shorter; shows; sickle; sieving; signal; significant; significant blood; signs; similar; similar results; simple; simulated; simulated transfusion; simulation; singapore; single; site; situations; size; size blood; small; smaller; snmvs; snp; snps; software; solid; solution; source; south; spc; spdp; special; species; specific; specifications; specificity; spectra; speed; spiked; spin; spleen; split; square; ssp; ssrbcs; stability; staff; stakeholders; standard; standard blood; standardized; starting; states; statistical; stay; stem cell; steps; sterile; storage; strategies; strategy; strength; strong; strs; students; study design; study group; study period; study population; subjects; subsequent; subset; substantial; substitution; successful; suitable; summer; supernatant; supplement; support; suppression; surface; surgeries; surgery; surgical blood; surveillance; survey; survival; susan; sxs; symptoms; syndrome; syringe; sysmex; systems; t cells; t&s; table; taco; taiwan; target; targeted; tasks; tattoo; team; technical; technique; technologists; technology; temperature; terms; tertiary; terumo; test results; tested; testing; testing method; testing time; tests; tetanus; tgf; thalassemia; thawed; thawing; therapeutic; therapeutic plasma; therapy; threshold; thrombin; thrombocytopenia; thrombotic; throughput; time; time donors; time period; time studies; time study; timely; tissue; titer; titer anti; titer results; tma; tms; tool; total; total blood; total number; total plasma; toxicity; tpe; tracking; traditional; training; trali; tranexamic; transfer; transfused; transfusion center; transfusion data; transfusion guidelines; transfusion laboratory; transfusion management; transfusion medicine; transfusion practice; transfusion process; transfusion protocol; transfusion quality; transfusion reactions; transfusion recipients; transfusion results; transfusion safety; transfusion sample; transfusion service; transfusion strategies; transfusion study; transfusion support; transfusion testing; transfusion therapy; transfusion transmission; transfusion volume; transfusion yield; transfusions; transmission; transplant; transplantation; transport; trauma; trauma patients; travel; treatment; tregs; trend; trial; triglyceride; trima; true; ttp; ttp patients; tube; tube method; tumor; turnaround; txa; txs; types; typing; typing results; u.s; ucb; underlying; understanding; underwent; unique; unit transfusion; united; units; universal; universal blood; university; unknown; unrelated; untreated; urgent; urine; usage; use; useful; users; uv1r; uva; vaccination; vaccine; validation; values; variable; variants; variations; varied; vein; venous; venous blood; verification; version; viability; viable; viral; virtuo; virus; viruses; vision; visual; vitro; vivo; volumes; voluntary blood; volunteers; vs.; vvr; vwf; waiha; walk; warm; washed; washing; wastage; waste; way; wbc; wbcs; wbd; wbf; weak; weak d; weekly; weeks; weight; white blood; wide; williams; window; women; work; workflow; working; workload; workup; world; wrong blood; x10; yale; year; yfv; yield; young; zealand blood; zika; zikv; zkv; zpp cache: cord-010119-t1x9gknd.txt plain text: cord-010119-t1x9gknd.txt item: #34 of 134 id: cord-010130-28bt3x25 author: Crocchiolo, R. title: Infections after T‐replete haploidentical transplantation and high‐dose cyclophosphamide as graft‐versus‐host disease prophylaxis date: 2015-03-26 words: 3519 flesch: 37 summary: GVHD prophylaxis was performed with Cy 50 mg/kg/day on days +3 and +4; tacrolimus 1 mg/day i.v. from day +5 (to reach a concentration of 5-15 ng/mL), or cyclosporine 3 mg/ kg/day i.v. from day +5 (to reach a concentration of 100-200 ng/mL), both up to day +100 and then tapered up to day +180, unless GVHD occurred; and mycophenolate mofetil 15 mg/kg 39 a day orally from day +5 to +35. When considering the timing of all episodes, bacterial infections occurred mostly between day 0 and +30, whereas viral infections/ reactivations between days +31 and +100, with 11.08 bacterial events/1000 pt-days between day 0 and +30, and 15.15 viral events/1000 pt-days between days +31 and +100 (Fig. 2) . keywords: analysis; bacterial; blood; cell; cmv; conditioning; consecutive; cumulative; cyclophosphamide; data; day; days; disease; events; follow; fungal; gvhd; haplo; haploidentical; hematopoietic; high; hsct; i.v; ifis; incidence; infections; low; marrow; median; months; myeloablative; non; observed; patients; period; pneumonia; post; prophylaxis; rate; reactivation; related; replete; risk; stem; study; transplantation; viral; year cache: cord-010130-28bt3x25.txt plain text: cord-010130-28bt3x25.txt item: #35 of 134 id: cord-014464-m5n250r2 author: Sole-Violan, J title: Lethal influenza virus A H1N1 infection in two relatives with autosomal dominant GATA-2 deficiency date: 2013-03-19 words: 99097 flesch: 51 summary: The application of the endotoxin activity assay was useful for bedside monitoring of endotoxemia in ICU patients. The aim of this study is to describe the clinical and epidemiological profi le of ICU patients receiving tigecycline (TGC) and to evaluate the potential benefi ts of TGC higher doses. keywords: abdominal; accepted; achieved; acid; acidosis; activation; active; activities; activity; acute; acute care; addition; adequate; ades; adjusted; administration; admission; adult patients; adults; adverse; age; agreement; aim; aims; airway; aki; albumin; alcohol; algorithm; altman; amino; ammation; ammatory; analysis; animals; anova; anp; anti; antibiotic; apache; approach; appropriate; approval; april; aprv; ards; ards patients; area; arrest; arterial; artery; asah; assay; assessment; assist; associated; association; auc; audit; available; average; bacterial; balance; baseline; bedside; benefi; best; better; bias; bicarbonate; biomarkers; bipap; bland; bleeding; blood; body; bolus; brain; brinogen; brinolysis; burn; cacy; calcium; calculated; cancer; capacity; cardiac; cardiac icu; cardiopulmonary; cardiovascular; care; care patients; cases; category; catheter; cause; cce; cells; center; central; centre; cerebral; ceus; challenge; changes; characteristics; chest; children; chronic; ci =; cial; ciency; cient; city; classifi; clinical; clinicians; clonidine; clot; cmh; coagulation; coagulopathy; coeffi; cohort; collected; colonization; combination; common; communication; comparable; comparison; complex; compliance; complications; concentration; conclusion; conditions; confi; consecutive; consecutive patients; consent; considered; consultant; consumption; continued; continuous; contraction; contrast; control; control group; control patients; conventional; coronary; correct; correlation; cost; course; cpp; creatinine; criteria; critical care; critically; cross; crypt; ctnt; cuff; cult; current; curve; cvc; cytokine; daily; damage; data; database; day mortality; days; death; death patients; december; decision; decrease; defi; degree; delirium; delivery; demographic; density; department; detection; development; device; diagnosis; diaphragm; diff; diff erence; direct; disaster; discharge; disease; distress; distribution; doctors; donation; donor; dose; drug; duration; dysfunction; earlier; early; ecg; ecmo; ect; ectiveness; ects; edema; education; eff; eff ect; effi; eld; elective; electronic; elevated; emergency; end; endothelial; endotoxemia; endotoxin; endpoint; energy; enteral; episodes; equipment; erence; erent; essential; evaluation; events; evidence; evlwi; excess; exclusion; exercise; expected; experience; experimental; exposure; expression; extracorporeal; factors; failure; families; family; feasible; feedback; feeding; female; fentanyl; fi ndings; fi rst; figure; fio; fl uid; focus; following; fraction; frequency; frequent; function; furosemide; future; gas; gdt; general; global; glucose; goal; good; greater; group; guidance; guidelines; haemorrhage; half; hand; handover; healthcare; healthy; heart; hemodynamic; heparin; higher; higher mortality; highest; history; hiv; hospital; hospital icu; hospital mortality; hours; human; hygiene; hypothermia; hypothesis; i.v; icp; icu admission; icu care; icu length; icu mortality; icu patients; icu stay; icus; identifi; idrs; igg; iii; il-6; ill; illness; imaging; impact; implementation; important; improved; improvement; incidence; increased; independent; index; individual; induced; infection; infl; information; informed; infusion; initial; initiation; injured; injury; insertion; insuffi; insulin; intensive; intensive care; intensivists; international; intervention; intracranial; intraoperative; intravenous; introduction; introduction patients; intubation; invasive; investigation; iqr; ischemia; isofl; isolated; items; january; japan; june; key; kidney; knowledge; laboratory; lactate; large; leading; left; length; levels; liberal; life; likely; limited; linear; literature; little; liver; local; logistic; long; longer; loss; lower; lps; lung; magnesium; main; major; majority; making; male; management; map; march; markers; maximum; mean; measurements; measures; mechanical; median; medical; medical patients; medicine; membrane; metabolic; methods; methods data; methods patients; mice; microcirculation; microvascular; midazolam; minutes; mitochondrial; mmhg; mmol; model; moderate; modifi; monitoring; monthly; months; morbidity; mortality; mortality rate; mrna; multiple; multivariate; muscle; n =; national; ndings; ned; need; negative; neurological; neurosurgical patients; new; ngal; non; nonsurvivors; norepinephrine; normal; novel; november; number; nurses; nursing; nutrition; objective; observational; obstetric; october; ohca; older patients; operating; optimal; order; organ; outcome; output; overall; oxygen; oxygenation; p =; pain; pao; parameters; participants; patients; pct; pdt; peak; pediatric; peep; people; percentage; performance; performed; perfusion; period; phase; physical; physicians; pigs; placebo; plasma; platelet; plr; pneumonia; points; poor; population; position; positive; possible; post; postoperative; potential; ppv; practice; predictive; predictor; preliminary; presence; present; pressure; prevalence; previous; primary; prior; problem; procedure; process; prognosis; program; prolonged; propofol; proportion; prospective; protein; protocol; psychological; pulmonary; pulse; purpose; quality; quantifi; questionnaire; questions; randomized; range; rapid; rate; rats; ray; rbc; recent; recommendations; records; recovery; reduced; reduction; reference; refl; region; regression; rehabilitation; related; relationship; relative; relevant; reliable; removal; renal; replacement; report; requirements; research; resistance; resources; respiratory; respondents; response; restrictive; results; resuscitation; retrospective; retrospective study; review; right; rise; risk; risk patients; role; room; routine; rrt; rst; rst group; safety; saline; samples; saps; satisfaction; saturation; scale; score; scoring; screening; second; secondary; sedation; selected; self; sensitivity; sepsis; september; septic patients; septic shock; serum; services; setting; severe; severe sepsis; severity; sham; shock; shock patients; short; shows; signifi; similar; single; site; small; society; sodium; sofa; software; specifi; staff; stage; standard; starch; start; statistical; status; stay; step; strategies; strategy; stratifi; stress; stroke; strong; studies; study; study group; study period; subjects; subsequent; successful; support; surgery; surgery patients; surgical icu; surgical patients; survey; survival; survivors; svo; symptoms; syndrome; system; systemic; systolic; table; target; tbi; tca; team; technique; teg; temperature; term; tertiary; test; tgc; thallium; therapeutic; therapies; therapy; thoracic; tidal; time; tissue; tnfα; tool; total; tracheal; tracheostomy; training; trali; transfer; transfusion; trauma; trauma patients; traumatic; treatment; trend; triage; trial; tube; type; uence; uid; uids; ultrasound; underwent; unit; university; urinary; urine; usa; use; values; vap; variability; variables; variation; vasopressin; vasopressors; vein; venous; ventilation; ventilatory; versus; volume; ward; water; weaning; week; weight; withdrawal; work; working; worse; years; young; ≤10 cache: cord-014464-m5n250r2.txt plain text: cord-014464-m5n250r2.txt item: #36 of 134 id: cord-014538-6a2pviol author: Kamilia, Chtara title: Proceedings of Réanimation 2017, the French Intensive Care Society International Congress date: 2017-01-10 words: 61107 flesch: 45 summary: We included ICU patients admitted for acute hypoxemic respiratory failure from a previous prospective trial [1] in whom FiO 2 was measured under oxygen mask using a portable oxygen analyzer. Introduction Relative adrenal insufficiency (RAI) is common in ICU patients, particularly during septic shock (1). keywords: account; accuracy; acinetobacter; activity; acute; acute respiratory; addition; administration; admission; adolescents; adult patients; adults; adverse; aeruginosa; age; aged; agents; aim; airway; aki; alveolar; analysis; annals; anne; antibiotics; anticoagulation; antixa; antoine; approach; ards patients; area; arf; arrest; arterial; aspergillosis; associated; association; aureus; automated; available; average; baclofen; bacterial; baseline; baumannii; bed; ben; beneficial; best; better; biological; biperiden; blood; body; brain; burn; cancer patients; cannula; carbapenems; carbon; cardiac; cardiogenic; cardiomyopathy; care; care unit; caregivers; caroline; cases; catheter; cause; cci; cell; center; central; cerebral; changes; characteristics; chest; children; christophe; chronic; circuit; circulatory; cirrhotic patients; citrate; clinical; cmv; cohort; cohort study; common; comparison; complications; concentrations; conclusion; concordant; conditions; consecutive patients; consequences; continuous; control; conventional; copd; correction; cost; count; cpb; creatinine; criteria; critical; csf; culture; curve; cvvh; cytokines; dad; daily; data; database; days; death; december; decision; decrease; definition; delay; delta; demographic; department; determined; development; devices; diagnosis; different; difficult; direct; discharge; discussion; disease; distress; donation; donors; doppler; dosage; dose; drug; duration; dysfunction; dyspnea; early; ecls; ecmo; eeg; effect; efficacy; elderly patients; emergency; emmanuel; encephalopathy; end; endothelial; endotracheal; endpoint; enteral; epidemiological; episode; equal; eric; esbl; evaluation; events; examination; experience; experimental; extracorporeal; extubation; extubation failure; factors; failure; families; family; fasting; features; feeding; fig; filter; fio; flow; fluid; following; france; françois; free; french; frequency; frequent; functional; general; glucose; good; greater; group; guidelines; guillaume; half; haloperidol; health; heart; hemodynamic; hemofiltration; hepatic; high; high mortality; higher; history; hospital; hospital mortality; hospitalization; hyperglycemia; hypertension; hypokalemia; hypophosphoremia; hypoxemic; icp; icu; icu admission; icu mortality; icu patients; icu stay; icus; ifd; ill; illness; imipenem; immune; immunocompromised; impact; implementation; important; improved; improvement; incidence; increase; independent; index; infection; inflammatory; influence; initial; injury; intensive; intensive care; interest; intracranial; intravenous; introduction; intubated; invasive; iqr; ischemia; isolated; january; jean; julien; kidney; knowledge; known; lack; lactate; large; laurent; leading; left; length; level; life; lifespan; like; literature; liver; logistic; longer; louis; low; lower; lung; lvef; lymphocyte; lymphopenic patients; macrophage; main; major; majority; making; male; management; marc; marie; marker; materials; mathieu; mean; measures; mechanical; mechanical ventilation; median; medical; medical icu; medicine; membrane; meta; methods; min; mmhg; mmol; model; moderate; mohamed; monitoring; monocentric; months; morbidity; mortality; mortality rate; mtdamps; mtdna; multicenter; multiple; multivariate; muscle; myocardial; médicale; n =; nasal; national; nebulizer; necessary; need; negative; nephrotoxic; neurological; neutropenia; neutropenic patients; new; nicolas; niv; nlr; nmba; non; normal; nosocomial; number; nurses; nutrition; objective; observational; observational study; obstructive; occurrence; old; olivier; onset; optimal; oral; order; organ; outcome; output; overall; oxygen; oxygenation; p =; pao; parameters; parenteral; participants; pathogens; patients; patients group; pav; pct; pediatric; percent; perfusion; period; philippe; physicians; physiotherapy; picu; pierre; plasma; platelet; pmv; pneumonia; point; poisoning; poor; population; position; positioning; positive; possible; post; postoperative; potassium; potential; pph; practice; predictive; predictors; presence; present; pressure; prevalence; previous; primary; prior; probability; procedures; process; prognosis; prolonged; prone; proportion; prospective; protein; protocol; psb; psv; pulmonary; purpose; quality; randomized; rapid; rate; reasons; receiving; recent; recommendations; reduction; refeeding; refractory; refusal; regimen; regional; regression; related; relationship; relatives; renal; replacement; report; research; resistant; respiratory; respiratory failure; response; responsible; responsiveness; results; resuscitation; retrospective; retrospective study; review; right; risk; risk factors; role; route; réanimation; safety; samples; saps; scale; score; secondary; sedation; seizures; sensitivity; sepsis; septic; septic patients; septic shock; serum; service; sessions; setting; severe; severity; sex; shock; shock patients; short; significant; signs; similar; single; sld; sofa; source; specific; specificity; staff; standard; statistical; status; stay; strategies; strategy; stroke; studies; study; study patients; study period; subgroup; subjects; support; surgery; surgical; survey; survival; survivors; sva; symptoms; syndrome; systematic; systolic; table; target; team; term; test; therapeutic; therapy; thierry; thomas; thrombosis; tidal; time; total; tpe; transfusion; transplantation; traumatic; treatment; trial; tube; type; ultrasound; unit; univariate; university; urinary; use; value; vap; variables; vascular; ventilation; versus; vincent; volume; waste; weaning; work; xavier; years cache: cord-014538-6a2pviol.txt plain text: cord-014538-6a2pviol.txt item: #37 of 134 id: cord-014976-546zaoxn author: None title: Publication only date: 2006-03-08 words: 51973 flesch: 49 summary: On admission before transplantation patient was presented with massive lymphadenopathy, anemia (Hb 76 g/L), WBC 24.8 x 109/L with absolute lymphocytosis (lymphocytes 98%) and thrombocytopenia 23 x 109/L. Pre-transplant conditioning consisted of high-dose cyclophosphamide and total body irradiation. There are publications about hyperkalemia in patients after renal transplantation but only few reports devote this phenomen in bone marrow transplantation patients. keywords: +30; a19; abct; abdominal; absolute; active; activity; acute; acute gvhd; addition; adequate; administration; adult; advanced; adverse; age; agent; aggressive; aim; alive; allogeneic; allogeneic stem; allogeneic transplantation; allografting; alloreactivity; alternative; aml; amphotericin; anaemia; analysis; anti; antibody; antifungal; apbsct; apheresis; aplastic; approach; asct; aspergillosis; associated; atg; autologous; autologous peripheral; autologous stem; autologous transplantation; available; background; bag; bcr; beam; benefit; better; biopsy; blood; blood cell; blood stem; blood transplantation; bmt; body; bone; bone marrow; busulfan; calcium; cancer; case; cd19; cd20; cd25; cd34; cd34+/kg; cd4; cell collection; cell count; cell dose; cell lymphoma; cell transplantation; cells; cellular; center; centre; cerebral; cfu; changes; chemotherapy; children; chimerism; chronic; chronic gvhd; class; clinical; cll; cml; cmv; cns; cohort; collection; colonies; colony; combination; combined; complete; complications; concentration; conclusion; conditioning; conditioning regimen; consecutive; control; conventional; cord; correlation; count; course; cryopreservation; cryopreserved; csa; csf; cultures; cutaneous; cycles; cyclophosphamide; cyclosporine; cytometry; daily; data; date; day; days; death; decrease; deficiency; depletion; detectable; development; dfs; diagnosis; differences; different; differentiation; disease; disorders; dli; dmso; dna; documented; donor; dose; dose chemotherapy; double; drug; duration; early; ecp; effective; effects; efficacy; endothelial; engraftment; epcs; etoposide; evaluated; evaluation; events; evidence; examination; experience; expression; extensive; factors; failure; family; feasible; female; fever; filgrastim; findings; flow; fludarabine; following; foxp3; free; freezing; frequency; function; fungal; gamma; good; grade; graft; granulocyte; group; growth; gvhd; haematopoietic stem; haploidentical; harvest; hct; healthy; hematological; hematopoietic; high; high dose; higher; histology; hla; hodgkin; hospital; host; host disease; hours; hsct; human; i.v; identical; iii; imatinib; immune; immunosuppressive; important; improvement; incidence; increase; induction; infection; infiltration; influence; infusion; initial; institute; intensity; introduction; invasive; involvement; irradiation; known; large; later; left; length; lesions; leukapheresis; leukemia; levels; like; limited; line; liver; long; loss; lower; lung; lymphoblastic; lymphocytes; lymphoid; lymphoma; lymphoma patients; main; major; majority; male; malignancies; malignant; management; markers; marrow; marrow transplantation; matched; mds; mean; median; median age; medical; melphalan; methods; methotrexate; mild; minimum; mismatched; mixed; mnc; mobilization; molecular; monitoring; monoclonal; mononuclear; mononuclear cells; months; mortality; mrd; mri; mscs; mtx; mucosa; mucositis; mud; multiple; myeloablative; myelofibrosis; myeloid; myeloma; myeloma patients; n=1; n=2; n=3; necessary; negative; neuroblastoma; neurological; neutropenia; neutrophil; new; nhl; nk cells; non; normal; number; objectives; old; older; opg; option; oral; origin; outcome; overall; pain; palifermin; partial; patients; pbpc; pbsc; pcr; peak; pediatric; peg; pegfilgrastim; percentage; period; peripheral; peripheral blood; peripheral stem; persistent; phase; plasma; platelet; plt; poor; populations; positive; post; posttransplant; potential; presence; present; previous; primary; prior; problems; procedure; process; processing; product; progenitor; prognosis; progression; proliferation; prolonged; prophylaxis; proportion; protein; protocol; pts; pulmonary; qrt; quality; range; rapid; rare; rate; reactions; reactivation; recipient; reconstitution; recovery; reduced; reduction; refractory; regimen; rejection; relapse; remission; renal; report; required; residual; resistant; resolution; response; results; retrospective; ric; right; risk; risk patients; rituximab; role; saa; safe; safety; salvage; samples; scid; sct; second; secondary; selection; sensitive; separator; serum; setting; severe; severity; sex; short; sibling; significant; signs; similar; single; skin; solid; source; specific; stable; stage; staining; standard; status; stem cell; steroids; storage; stromal; studies; study; subset; successful; sufficient; support; survival; survivors; symptoms; syndrome; system; systemic; t cell; tandem; target; tbi; tcr; term; thalassemia; thawing; therapeutic; therapy; time; tissue; tnc; total; toxicity; transfusion; transplantation patients; transplanted; transplanted patients; treatment; treosulfan; trm; tumors; type; undergone; underwent; university; unrelated; use; values; viability; viral; volume; wbc; weeks; weight; white; x10; years cache: cord-014976-546zaoxn.txt plain text: cord-014976-546zaoxn.txt item: #38 of 134 id: cord-015021-pol2qm74 author: None title: Third International Congress on the Immune Consequences of Trauma, Shock and Sepsis —Mechanisms and Therapeutic Approaches date: 1994 words: 162543 flesch: 45 summary: Ever since we know the role of endotoxins in the pathophysiology of sepsis, antibodies against the S-and R-LPS have also been detected in sepsis patients. In sepsis patients, the CD]4+/CD16+ cells can become a major population with more than 50% of all monocytes in 3 of 18 patients and with more than 500 cells/mm 3 in 4 of 18 cases. keywords: + +; 24h; 48h; abdominal; abdominal sepsis; ability; able; abnormalities; abscess; absence; absolute; account; accumulation; acid; acinar; activation; activities; activity; acts; acute; acute phase; addition; adequate; adherence; adherent; adhesion; administration; admission; adult; aeruginosa; affected; affinity; agents; aggressive; aim; albumin; alcohol; allogeneic; allograft; alpha; alterations; altered; alternative; alveolar; amino; amounts; analysis; anastomotic; anesthesia; anesthetized; animals; anova; antagonist; anti; antibiotics; antibodies; antibody; antigen; antiinflammatory; antimicrobial; antioxidants; antisense; antithrombin; aorta; aortic; apache; apoptosis; apparent; appearance; application; approach; appropriate; ards; ards patients; area; arf; arginine; arterial; arterial blood; artery; assay; assayed; assessment; associated; association; atp; attempt; attention; augmented; autologous; available; b cells; baboons; bacteremia; bacterial; bacterial sepsis; bactericidal; balance; balb; barrier; basal; baseline; basis; beginning; beneficial; benefit; best; beta; better; bfgf; bgc; binding; bioassay; biochemical; biological; bleeding; blind; blockade; blocking; blood; blood cells; blood flow; blood levels; blood loss; blood mononuclear; blood pressure; blood samples; blood transfusion; bmmc; body; bolus; bone; boston; bowel; bpi; bradykinin; bronchoalveolar; bum; burn; burn injury; burn patients; burned; burst; c mice; c3a; c3h; ca2; calcium; calculated; camp; cancer; cancer patients; candida; capable; capacity; capillary; cardiac; cardiovascular; care; cascade; cases; cathepsin; catheter; cause; cavity; cd14; cd16; cd18; cd3; cd4; cd8; cdlla; cea; cecal; ceil; cell activation; cell adhesion; cell death; cell injury; cell surface; cell types; cells; cellular; center; central; certain; cfu; chain; challenge; changes; characteristics; characterization; characterized; chemiluminescence; chemotactic; children; choice; cholesterol; chow; chronic; circulating; circulatory; cirrhosis; cirrhotic; class; classes; classification; clearance; clinical; clinical study; close; clotting; clp; cmi; cmv; cns; cntf; coagulation; coil; cold; coli; collagen; collected; colony; combination; combined; committee; common; communication; comparable; compare; comparison; complement; complete; complex; complexes; complicated; complications; components; composition; compounds; concentrations; concept; conclusion; concomitant; conditions; consecutive; consequence; considerable; constant; constitutively; consumption; contact; content; continuous; contraction; contrast; contributes; contribution; control; control animals; control cells; control group; control patients; conventional; coronary; correlate; correlation; corresponding; cortisol; count; course; coverage; cp-0127; criteria; critical; cross; crp; crp levels; crucial; csf; cultured; current; cutaneous; cvvh; cytokine levels; cytokine production; cytokine release; cytokine response; cytokines; cytokines tnf; cytometry; cytoplasmic; cytosolic; cytotoxic; cytotoxicity; daily; damage; data; dawley; days; days post; death; decreased; defect; defense; deficient; degradation; degranulation; degree; dehydrogenase; delayed; deleterious; delivery; density; department; dependent; deposition; depressed; dept; design; detectable; detection; determination; determined; development; dfo; diagnosis; diet; differences; different; differential; differentiation; difficult; diffuse; diminished; direct; discussion; disease; disorders; disruption; distal; distinct; distress; distribution; disturbances; dna; domain; donors; dose; double; drainage; drug; dth; duration; dxs; dysfunction; e-75; e.coli; e.g.; earlier; early; early sepsis; edema; effect; effective; effectiveness; efficacy; efforts; ehec; elastase; elderly; elderly patients; elective; elements; elevated; elevated levels; elevation; elimination; elisa; endocrine; endogenous; endothelial; endothelial cells; endotoxemia; endotoxin; endotoxin levels; endotoxin release; endotoxin shock; energy; enhanced; enhancement; enteral; entry; enzymes; epithelial; equivalent; erythrocytes; escherichia; essential; ester; et levels; etc; ethanol; evaluated; evaluation; events; evidence; evident; evoked; exact; example; excessive; exchange; excretion; exhibit; experimental; exposure; expression; extensive; extent; extraction; facs; factor; failure; fall; family; fashion; fast; fatal; fatty; features; fed; feeding; female; femoral; fever; fiber; fibrinogen; fibroblasts; field; filgrastim; final; findings; flora; flow; fluid; fluorescence; fmlp; focus; fold; following; follows; food; formation; forms; formula; fraction; fragments; free; frozen; function; future; gain; gamma; gap; gapdh; gastric; gastrointestinal; gel; gene; general; generalized; generation; genomic; germany; glucose; glutamine; glutathione; gms; good; graft; gram; gramnegative; granulocyte; greater; group; group b; group ii; group patients; growth; gsh; gtn; gut; gwt; h202; ha-1a; haemorrhage; half; hand; healing; healthy; heart; hej; help; helper; hemodynamic; hemoglobin; hemorrhagic; hemorrhagic shock; heparin; hepatectomy; hepatic; hepatitis; hepatocellular; hepatocytes; high; high dose; high levels; higher; highest; hind; hirudin; histamine; histological; hla; homeostasis; hormone; hospital; host; host response; hours; hrs; human; human blood; human sepsis; humoral; hydrogen; hypersensitivity; hypotension; hypothesis; hypoxia; i.e.; i.p; i.v; ibuprofen; icam-1; icu; identical; ifn; igg; igm; iii; il-1; il-1ra; il-2; il-3; il-4; il-6; il-6 levels; il-6 production; il-8; il6; ill patients; illness; imipenem; immediate; immune; immune cells; immune function; immune response; immune system; immunity; immunization; immunoglobulin; immunological; immunology; immunosuppression; impact; impaired; impairment; important; important role; improved; improvement; incidence; incision; increased; incubation; index; indicator; indirect; individuals; induced; inducible; induction; infected; infection; infiltration; inflammation; inflammatory; inflammatory cells; inflammatory cytokines; inflammatory mediators; inflammatory response; influence; influx; infusion; inhalation; inhibited; inhibitor; inhibits; initial; initiation; injured; injuries; injury; injury severity; inos; institute; insufficiency; intact; integrins; integrity; intensive; interactions; interferon; interleukin; interstitial; intervals; intervention; intestinal; intraabdominal; intracellular; intraperitoneal; intravascular; intravenous; introduction; invading; invasion; investigations; involved; involvement; ionomycin; ip3; irf; iron; irradiation; irreversible; ischemia; isolated; ivig; kallikrein; keto; key; kidney; killing; kinase; kinetics; kit; knee; knowledge; known; kupffer; l ~; laboratory; lack; lactate; lal; laparotomy; large; late sepsis; later; lavage; lbp; lead; leading; leakage; left; leh; length; lesser; lethal; lethality; leukocytes; levels; lewis; ligand; ligation; light; like; likely; limb; limited; limulus; lipid; lipopolysaccharide; liposomes; little; liver; liver blood; liver cell; liver failure; liver injury; local; localized; long; longer; loss; lower; lps; lps activation; lps administration; lps challenge; lps immune; lps injection; lps lethality; lps release; lps stimulation; lps treatment; lra; ltb4; lung; lung injury; lymphocytes; lymphoid; lymphokine; lysate; lysosomal; m.d; mab; macrophages; mad; magnitude; mainly; major; major surgery; malaria; male; malignant; management; manner; map; marked; markers; marrow; mass; massive; mast; mast cells; materials; matrix; maximal; maximum; mda; mean; measurements; mechanical; mechanisms; median; mediators; medical; medicine; medium; membrane; mesenteric; metabolic; metabolites; methods; mhc; mice; microcirculatory; microorganisms; microscopy; microvascular; mid; mif; migration; mild; minutes; mip; mitochondrial; mitogen; mixed; ml blood; ml lps; mln; mmhg; moab; mobilization; model; modified; mods; modulate; mof; molecular; molecules; monitoring; monoclonal; monocytes; monocytic; mononuclear; mononuclear cells; morbidity; mortality; mouse; mps; mrna; mucosal; multiple; multiple organ; multiple trauma; munich; murine; muscle; muscle cells; myeloid; myeloperoxidase; myocardial; n =; n t; n=10; n=12; n=5; n=6; n=7; n=8; nac; natural; nature; near; necessary; necrosis; necrosis factor; need; negative; negative sepsis; neopterin; nervous; network; neutralizing; neutropenia; neutrophils; new; ngf; nitric; nitrogen; nma; nmma; nmol; no2; nodes; non; normal; northern; nosocomial; novel; number; numerous; nutrition; oatmeal; objectives; observation; observed; occurrence; occurring; odn; oil; onset; open; operation; order; organ; organ dysfunction; organ failure; organ injury; organisms; origin; osf; outcome; output; overall; oxidase; oxidative; oxide; oxygen; oxygenation; p.g; p2 cells; p75; p<0.001; p<0.05; paf; pancreatic; pancreatitis; pap; parallel; parameters; parenteral; partial; particular; pathogenesis; pathogenic; pathological; pathophysiological; pathophysiology; pathways; patients; patients blood; patients levels; pattern; pbmc; pcr; peak; peptide; percentage; period; peripheral; peripheral blood; peritoneal; peritonitis; permeability; peroxidation; persistent; pge; pge2; phagocytic; phagocytic cells; phagocytosis; phase; phase response; phenomenon; phenotype; phosphate; phx; physiologic; pigs; pituitary; pivotal; pkc; pla2; placebo; placebo group; placebo patients; plasma; plasma concentrations; plasma endotoxin; plasma levels; plasma samples; plasma tnf; platelet; play; plf; pma; pmn; pmnl; pmns; pmol; pneumonia; po2; pof; points; polymorphonuclear; polypeptide; polytrauma; pool; poor; population; portal; positive; possibility; possible; post; post lps; postischemic; postoperative; posttraumatic; potential; powerful; ppm; precise; preclinical; precursor; preliminary; preoperative; preparation; presence; present; present study; presentation; pressure; pretreated; pretreatment; prevention; previous; primary; priming; prior; probes; problems; procedure; process; processes; produced; production; products; profound; progenitor; prognosis; proliferate; proliferation; prolonged; promising; promoter; pronounced; properties; prophylactic; prophylaxis; proportion; prospectively; prostacyclin; prostaglandin; protease; protective; protein; proteinases; proteolytic; protocol; pseudomonas; pts; ptx; pulmonary; puncture; purified; purpose; quantitative; question; rabbits; radicals; rain; randomized; range; ranitidine; rapid; rate; rats; rbpi23; reaction; reactive; recent; receptor; recipients; recombinant; recovery; recruitment; reduced; regard; region; regional; regression; regulation; regulatory; related; relationship; relative; relaxation; release; releasing; relevance; relevant; remote; renal; repair; reperfused; reperfusion; reperfusion injury; replacement; reported; reports; research; resection; resistance; respect; respiratory; response; response results; response syndrome; responsible; responsiveness; results; resuscitation; review; rhg; ringer; rings; rise; risk; role; routine; s.c; safety; saline; salmonella; samples; sampling; sbi; scald; school; score; scoring; second; secondary; secrete; secretion; sections; selected; selectin; sem; sensitive; sensitivity; separate; sepsis; sepsis induction; sepsis model; sepsis score; sepsis study; sepsis syndrome; septic animals; septic complications; septic group; septic organ; septic patients; septic response; septic shock; septicemia; sequelae; sequences; sequential; sequestration; sera; serial; series; serine; serum; serum il-6; serum levels; serum tnf; setting; severe; severe sepsis; severe trauma; severity; sex; sham; shed; shed blood; shedding; shock; shock group; short; shunt; sicu; signal; significant; significant increase; signs; similar; simple; simultaneous; single; sirs; site; situ; situation; size; skeletal; skin; slices; sll-6r; small; smooth; sod; sodium; soluble; soluble tnf; solution; source; space; special; species; specific; specificity; spleen; spleen cells; splenic; sprague; stable; stages; staining; standard; start; state; statistical; status; stay; step; stimulated; stimulation; stimuli; stimulus; stnfr; strains; strategies; strategy; stress; strong; structure; studies; study; study period; study results; subjects; subsequent; subsets; substances; substantial; substrates; successful; suffering; sufficient; summary; superior; supernatants; superoxide; supplemented; supply; support; suppression; surface; surgery; surgical; surgical patients; surgical trauma; survival; surviving; survivors; susceptibility; symptoms; syndrome; synergistic; synthase; synthesis; synthetic; system; systemic; systemic inflammatory; t cells; target; taurine; tbsa; techniques; temperature; temporary; tendency; terminal; terms; test; tested; testing; tgf; tgf-131; therapeutic; therapies; therapy; thermal; thermal injury; thickness; thl; thoracic; thrombin; thromboxane; thymic; thymus; time; tissue; tissue injury; tn3; tnf; tnf activity; tnf levels; tnf mab; tnf mrna; tnf production; tnf receptors; tnf release; tnf treatment; tnfa; tnfc~; tool; total; toxic; toxicity; toxins; tpn; tract; transcription; transduction; transferrin; transfusion; transient; transit; translocation; transmembrane; transplantation; transplanted; transport; trauma patients; trauma sepsis; traumatic; treated; treatment; treatment group; trials; trigger; tumor; type; ulcers; unchanged; unclear; underlying; understanding; underwent; units; university; unknown; untreated; uptake; urinary; usa; use; useful; valuable; values; variables; variety; vascular; vasoconstriction; vehicle; vein; venous; venous blood; ventilated; ventilation; venules; verapamil; versus; vessels; viable; viral; vitro; vivo; volume; volunteers; wall; wbc; weeks; weight; white; white blood; wide; wilcoxon; wistar; work; wound; xanthine; years; zymosan cache: cord-015021-pol2qm74.txt plain text: cord-015021-pol2qm74.txt item: #39 of 134 id: cord-015024-2xzc0uc5 author: None title: ESICM 2010 WEDNESDAY SESSIONS 13 October 2010 date: 2010-08-31 words: 84465 flesch: 50 summary: The primary end point of this study was to evaluate the RVD of the IVC in ICU patients with spontaneous breathing. ICU patient with spontaneous breathing and signs of hypoperfusion (oliguria, mottles, serum lactate level [2 mmol/l) were eligible after the approval of the local Ethics Committee. keywords: 24h; abdominal; ability; acc; acid; acidosis; acknowledgment; activation; activities; activity; acute; addition; adiponectin; administration; admission; adult; adult patients; advanced; adverse; affected; age; aim; aims; airway; albumin; algorithm; alveolar; ambulance; ammonia; anaesthesia; analysis; animals; anova; anti; antibiotics; apache; approach; appropriate; approval; aprv; ards; ards patients; area; arf; arginine; arrest; arterial; artery; artificial; assessment; associated; association; audit; available; average; bacterial; bal; baseline; basis; bed; bedside; benefit; best; better; bias; blood; blood pressure; bmi; body; bolus; brain; breathing; breaths; bundle; burn; burn patients; calculated; campaign; cancer; capacity; cardiac; cardiovascular; care; care nurses; care patients; care unit; cases; catheter; cause; cd40; cefazolin; cells; central; centre; cerebral; chair; challenge; changes; characteristics; chronic; cicu; circulatory; citrate; citrulline; clearance; clinical; cmh; coagulation; cognitive; cohort; collaboration; collection; committee; common; comparable; comparison; complex; compliance; complications; concentrations; conclusions; conditions; confidence; consecutive patients; consent; continuous; contrast; control; control group; conventional; coronary; correct; correlation; course; crcl; creatinine; criteria; critical care; critical patients; critically; crrt; css; cuff; culture; current; curve; cvp; daily; data; database; day; days; death; december; decision; decrease; delirium; delivery; demographic; department; design; determined; deviation; diagnosis; diameter; diastolic; diazepam; differences; different; difficult; discharge; disease; dobutamine; doctors; doppler; dose; dppalg; drug; duration; dysfunction; early; echocardiography; ecls; ecmo; edema; education; effect; effective; efficacy; emergency; encephalopathy; end; energy; enteral; environment; eol; equipment; errors; esicm; essential; established; estimate; ethics; evaluation; events; evidence; examination; existing; expansion; expected; experienced; experimental; expression; extracorporeal; extubation; face; factors; failure; family; feeding; female; fig; findings; finger; flow; fluid; following; free; frequency; function; gas; gastric; gender; general; genes; gln; global; glucose; goal; good; grade; grant; greater; group; grv; guidelines; gut; h1n1; half; hand; hcl; head; health; heart; hemodynamic; hepatic; high; higher; highest; hli; hopelessness; hospital; hospital mortality; hrqol; human; hypotension; hypothermia; iap; icu admission; icu care; icu discharge; icu mortality; icu nurses; icu patients; icu stay; icus; iii; il-6; ill; illness; immune; impact; impaired; important; improve; improvement; incidence; inclusion; increase; independent; index; induced; induction; infection; inferior; inflammation; inflammatory; influence; information; infusion; initial; injury; insertion; insufficient; intensive; intensive care; intensivists; interactions; internal; international; interventions; intracranial; intravenous; introduction; invasive; involved; iqr; isolated; issues; itu; ivc; january; key; kidney; knowledge; laboratory; lack; lactate; lactic; large; later; lead; leading; left; length; levels; life; likely; linear; literature; liver; lmol; local; logistic; longer; loss; low; lower; lps; lung; lvef; main; major; making; male; management; mann; manual; map; markers; mean; measured; measurements; mechanical; mechanical ventilation; mechanisms; median; medical; medical icu; medical patients; medicine; membrane; metabolic; methods; mice; min; mitochondrial; mixed; mmhg; mobilization; model; moderate; mods; monitoring; months; morbidity; mortality; multiple; muscle; myocardial; n =; necessary; need; negative; neurological; new; nirs; non; norepinephrine; normal; number; nurses; nursing; nutrition; obese patients; objectives; observational; observational study; observed; occlusion; october; old; onset; optimal; oral; order; organ; outcome; output; overall; oxygen; oxygenation; p =; p group; p value; pao; parameters; patients; peak; peep; performance; perfusion; period; perioperative; personal; pfo; phase; phrenic; physical; physicians; physiological; picco; pigs; placement; plasma; pneumonia; point; policy; poor; population; position; positive; possible; post; postoperative; potential; ppv; practice; predictive; predictors; presence; present; pressure; prevalence; prevention; previous; primary; prior; problems; procedure; process; professional; prognostic; prolonged; prone; propofol; proportion; prospective; prospective study; protein; protocol; pulmonary; pulse; purpose; qualitative; quality; questionnaire; r =; randomized; range; rapid; rate; rats; rbc; reasons; recent; recommended; recorded; recovery; reduced; reduction; reference; regional; regression; regulatory; related; relationship; relative; reliability; removal; renal; report; required; research; respiration; respiratory; responders; response; responsiveness; results; resuscitation; retrospective; review; rifle; right; risk; risk patients; role; routine; safety; saline; samples; saps; saturation; scale; score; scoring; scvo; secondary; sedation; seizures; sensitivity; sepsis; septic patients; septic shock; series; serum; setting; severe; severe sepsis; severity; sex; shift; shock; shock patients; significant; similar; single; sirs; sivelestat; size; skills; small; sodium; sofa; software; solution; spain; special; specific; specificity; spontaneous; staff; stages; standard; start; state; statistical; status; stay; sto2; strain; strategies; strength; stress; stroke; strong; structural; student; studies; study; study patients; study period; subjects; supine; support; surgery; surgery patients; surgical patients; survey; survival; surviving; survivors; svv; symptoms; syndrome; system; systemic; systolic; table; tbsa; tcd; team; technique; technology; temperature; test; thenar; therapeutic; therapy; tidal; time; tissue; tnfa; tool; total; training; transfer; transfusion; trauma; traumatic; treated; treatment; trial; tube; type; underwent; ungal; uniplas; unit; university; unknown; use; useful; values; vancomycin; vap; variables; variation; vascular; venous; ventilated; ventilation; ventilatory; ventricular; volume; volunteers; ward; ward patients; weaning; week; weight; weight patients; whitney; women; work; working; years cache: cord-015024-2xzc0uc5.txt plain text: cord-015024-2xzc0uc5.txt item: #40 of 134 id: cord-015090-n6f4xupw author: None title: PS 339-563 date: 2005-09-10 words: 26303 flesch: 51 summary: Propofol is often used as a sedative in ICU patients. The aim of this study was to suggest how the computation of ÄSID should be sophisticated in order to obtain a good correspondence with BE in ICU patients. keywords: access; acth; activity; acute; addition; admission; adr; adult; age; aim; airway; analysis; apache; approach; arrest; arterial; artery; assessment; associated; athens; attitudes; available; average; bed; beds; better; blood; body; brain; breathing; bronchoscope; cardiac; care; cases; catheter; cause; center; central; cerebral; cervical; changes; chest; children; clinical; coagulation; collected; coma; complications; concentration; conclusion; consecutive; continuous; control; correlation; cortisol; costs; course; criteria; critical; cuff; daily; damage; data; days; death; decision; delivery; department; diagnosis; difference; difficult; disease; dislocation; donation; donors; dose; drainage; early; elective; emergency; encephalopathy; end; endotracheal; evaluation; factors; failure; family; feeding; fio2; fluid; following; foreign; free; function; gcs; general; glucose; good; grade; group; hand; head; health; heart; hemodynamic; higher; hospital; hours; icp; icu; icu patients; icus; ill; illness; impact; impaired; incidence; increase; index; infection; information; infusion; injury; insertion; intensive; intensive care; intracranial; introduction; intubation; invasive; lack; large; left; length; let; levels; life; lipid; lobe; logistic; longer; lower; main; making; management; mean; measured; measurements; mechanical; median; medical; melatonin; members; methods; mif; min; mmol; model; monitoring; months; mortality; neck; need; negative; netherlands; neurological; new; nom; non; normal; nosocomial; nrbc; number; nurse; nursing; nutritional; objective; onset; order; organ; outcome; output; p<0.001; parameters; participants; patients; pct; pea; percutaneous; period; pharmacy; physicians; picu; placement; plasma; platelet; pneumonia; poor; population; positive; postoperative; predictive; presence; present; pressure; primary; procedure; process; prolonged; propofol; prospective; protein; protocol; pulmonary; randomized; range; rate; ratio; reasons; regression; renal; required; respiratory; response; results; retrospective; right; risk; safe; samples; scale; scan; score; scvo2; second; secondary; sepsis; septic; septic patients; serum; severe; severity; shock; significant; signs; similar; sirs; solution; specific; spinal; spine; staff; standard; statistical; stay; studies; study; support; surgery; surgical; survival; survivors; syndrome; system; table; tbi; team; technique; teg; temperature; test; therapeutic; therapy; time; tissue; total; tracheal; tracheostomy; training; transferred; transfusion; transport; trauma; trauma patients; treatment; tube; type; underwent; unit; united; university; urine; use; useful; vad; values; vap; variables; venous; ventilation; ventilatory; ventricular; volume; washing; week; years cache: cord-015090-n6f4xupw.txt plain text: cord-015090-n6f4xupw.txt item: #41 of 134 id: cord-015126-cyhcbk1j author: None title: PS 0036-0344 date: 2007-08-25 words: 59258 flesch: 52 summary: The aim of this clinical trial is to study CIP in ICU patients (pts) after surgical procedures. The physiological condition of ICU patients is marked by rapidly evolving and frequently life-threatening derangements as well as 'silent' yet important alterations in homeostasis. keywords: 95%ci; abdominal; accuracy; acid; action; activity; acute; adequate; adma; administration; admission; adrenal; adverse; age; aim; airway; alpha; anaesthetic; analgesia; analysed; analysis; anesthesia; anesthetized; aneurysm; animals; antibiotic; aortic; apache; apd; application; appropriate; ards; ards patients; areas; arg; arrest; arterial; arterial blood; arteries; artery; aspiration; assessment; associated; association; atc; average; bacterial; baseline; bed; bedside; best; better; bipap; blood; blood pressure; body; brain; breathing; burn; cardiac; care; care patients; care unit; cases; catheter; cause; cci; cells; central; cerebral; cfi; challenge; changes; characteristics; chest; children; chronic; cim; cip; cipnm; circulatory; clinical; clp; cmh2o; cmv; cohort; collected; coma; comfort; common; compliance; complications; concentrations; conclusion; consecutive; consecutive patients; consent; constant; continuous; contractile; contrast; control; control group; conventional; copd; correlated; correlation; cortisol; count; course; cpap; criteria; critical; crp; csf; cultures; curves; cvp; daily; damage; data; days; death; december; decision; decrease; demographic; department; dependent; deterioration; determination; determine; development; deviation; device; diabetes; diagnosis; diastolic; difference; discharge; disease; distress; distribution; doctors; donation; donors; dose; drug; duration; dysfunction; early; effective; effects; elevated; emergency; end; endotracheal; energy; eol; episodes; established; ethanol; etomidate; evlw; evolution; examination; exchange; experience; experimental; expression; extravascular; factors; failure; family; findings; fio2; flag; flow; fluid; following; frequency; frequent; function; gas; general; germany; glasgow; global; glucose; good; group; guidelines; hand; head; healthy; heart; help; hemodynamic; hemofiltration; hemorrhage; hfov; higher; hospital; hospital mortality; hours; hrqol; hrs; hydrocortisone; hypothermia; hypoxemia; icu; icu mortality; icu patients; icu stay; icus; iii; il-6; ill; illness; immune; impact; important; improve; improvement; incidence; increase; index; induced; induction; infants; infection; inflammation; inflammatory; influence; information; infusion; initial; injured; injury; ino; inotropic; insulin; intensive; intensive care; intervention; introduction; intubation; invasive; ischemia; isolated; itbvi; january; knowledge; laboratory; lactate; large; left; length; level; life; limited; linear; liver; loading; local; logistic; long; los; lower; lps; lung; lvef; main; major; majority; male; management; mann; map; marker; maximal; maximum; mean; mean age; measurements; measures; mechanical; mechanical ventilation; median; medical; medicine; mesenteric; methods; mice; microcirculation; microvascular; mild; min; minutes; mitochondrial; mixed; mmhg; mmol; model; moderate; monitored; monitoring; months; morbidity; mortality; multiple; multivariate; muscle; necessary; need; negative; neurological; new; nippv; nmba; noisy; non; normal; number; nurses; objective; observational; observed; old; onset; operation; order; organ; outcome; output; overall; oxygenation; p<0.001; p<0.05; pain; pao2; parameters; patients; patients blood; pattern; pct; pcvcs; peak; pediatric; peep; percentage; perfusion; period; peripheral; peritonitis; pigs; placebo; plasma; pneumonia; point; poor; population; positive; possible; post; postoperative; potential; ppv; practice; predictive; predictor; preload; presence; present; pressure; prevalence; previous; primary; prior; procedure; process; prognosis; prolonged; propofol; propranolol; prospective; protein; protocol; psv; pts; pulmonary; pulse; quality; quantitative; radial; range; rate; ratio; rats; rbc; reactive; recent; recovery; recruitment; reduction; reference; regional; regions; regression; related; relationship; relative; renal; research; resistance; respiratory; respiratory failure; responders; response; responsiveness; results; resuscitation; retrospective; right; risk; risk patients; role; saline; samples; sap; saps; saturation; scale; score; second; sedation; sensitivity; sensors; sepsis; septic; septic patients; septic shock; series; serum; set; settings; severe; severity; sham; shock; shock patients; short; significant; signs; similar; single; sirs; small; sofa; software; solution; specificity; spontaneous; square; staff; standard; statistical; status; stay; stimulation; sto2; strategy; stroke; studies; study; support; surgery; surgical; survival; survivors; svi; svo2; svv; syndrome; system; systemic; systolic; table; target; tbi; technique; test; testing; therapeutic; therapy; thermodilution; thoracic; tidal; time; tissue; tnf; tolerance; total; tracheal; tracheostomy; tract; transfer; transfusion; trauma; trauma patients; traumatic; treatment; tube; type; ultrasound; underlying; unit; univariate; university; use; useful; values; vap; variables; variation; vascular; vasopressor; vein; venous; ventilated; ventilation; ventilatory; ventricular; volume; vri; water; weaning; week; weight; whitney; window; withdrawal; years cache: cord-015126-cyhcbk1j.txt plain text: cord-015126-cyhcbk1j.txt item: #42 of 134 id: cord-015369-72cjogxz author: None title: 50th Annual Meeting of the Austrian Society of Surgery. Vienna, June 18–20, 2009. Guest Editors: Albert Tuchmann, Erhard Schwanzer, Benedikt Walzel date: 2009 words: 71211 flesch: 45 summary: eröffneten Aortenbogen in die Aorta deszendens vorgeschoben, anschließend wird mit der Dacron Hälfte der Prothese der Aortenbogen und die distale Aorta aszendens ersetzt. Das postoperative Kontroll-und Stimulationsschema beträgt 9 Monate, in denen die Aussprossung der Axone in monatlichen Abständen evaluiert wird. keywords: 2001; 211h; abdomen; abdominal; aber; abhängig; abklärung; ablation; abnormal; abscess; absence; abteilung; access; achalasia; acid; acidic; acr; activity; acute; additional; adenocarcinoma; adequate; adhesion; admission; adrenal; adrenalectomy; advanced; advantage; adverse; affected; age; aggressive; aim; allen; allerdings; alpha; als; als auch; alter; alternative; amputation; analyse; analyse der; analysiert; analysis; anastomosis; anderen; andererseits; aneurysms; anforderungen; angesehen; anhand; anhand der; animals; anorektalen; anschließend; anstieg; anterior; anti; antibiotic; antireflux; antitpo; anwendung; anzahl der; aorta; aortic; apollon; apoptosis; apoptotic; appearance; appendectomy; appendicitis; appendix; application; approach; arbeit; arch; area; arterial; artery; asa; asd; assessment; associated; auch; auch bei; auch der; auch mit; auf; auf das; auf der; auf eine; aufgrund; aufgrund der; auftreten; aufwärmen; august; aus; ausgedehnten; austria; autologous; available; average; avr; awp; background; band; banding; bariatric; barrett; basis; bedeutung; befund; behandelt; behandlung; bei allen; bei der; bei einer; bei n; bei patienten; beiden; beim; benefit; benign; beobachtet; beobachtungszeitraum; bereich; bereich der; bereits; berichten; berleben; berlebensraten; beschrieben; bestand; bestrahlung; betrug; better; bevacizumab; bewährt; bezüglich; bezüglich der; bh4; bilateral; bile; biocompatible; biological; biopsies; biopsy; bis; bisher; bite; bladder; bleeding; blieb; block; blood; blot; blutung; bmi; bml; board; body; bone; bos; bowel; brain; breast; bridge; brust; bypass; bzw; cabg; calcitonin; cancer; cancer patients; carcinoid; carcinoma; carcinomatosis; cardiac; cardiac surgery; care; cases; catheter; cause; cav; cbd; cd163; cells; center; centrimag; cervical; changes; chemotherapeutic; chemotherapy; chest; children; chirurgen; chirurgie; chirurgische; choice; cholecystectomy; cholecystitis; choledocholithiasis; chronic; classification; cle; clear; clinical; clip; closed; closure; colitis; collagen; colon; colonic; colonoscopy; colorectal; columnar; combination; combined; common; comparable; comparison; complete; complex; compliance; complications; concept; conclusions; condition; congenital; consecutive patients; conservative; contamination; contrast; control; controversial; conventional; coronary; correlation; cosmesis; cosmetic; cost; course; cpb; crc; creatinine; criteria; crohn; crp; crs; crt; cuff; curative; cxcr4; dabei; daher; daily; damage; damit; daraus; dargestellt; das; dass; dass die; dass eine; data; daten; davon; days; dazu; dcm; death; debridement; december; decreased; deep; defects; defektdeckung; degree; delayed; delivery; dem; density; department; der; der aorta; der behandlung; der betroffenen; der brust; der der; der diagnostik; der durch; der eigenen; der expression; der folge; der fälle; der gruppe; der hand; der infektion; der laparoskopischen; der leber; der linken; der literatur; der mittleren; der multivariaten; der neoblase; der nicht; der oberen; der operation; der patient; der pleura; der postoperative; der präoperativen; der tumor; der untersuchung; der vorliegenden; der wahl; der ü; des; descending; deshalb; design; deutlich; development; device; dgp; diabetes; diabetic; diagnose; diagnosis; diagnostiziert; diameter; die; die aorta; die bei; die chirurgische; die daten; die der; die durchschnittliche; die mit; die neoadjuvante; die ü; dieser; diet; differences; different; difficult; dilatation; direct; discharged; disease; diskutiert; disorders; dissection; distal; distant; distribution; donation; donor; doppler; drainage; drei; dressing; drug; dss; duration; durch; durch die; durch eine; durchgeführt; durchgeführt und; durchgeführt werden; durchschnittlich; dysphagia; early; easy; ecmo; effective; effects; efficacy; efomycine; egfr; eigenen; ein patient; eine; eine der; eine seltene; einerseits; einfluss; eingriff; einsatz; einsatz der; einzelnen; elderly patients; elective; elevated; emergency; endoleak; endoscopic; endoskopische; endothelial; endovascular; energy; enterocolitis; enterocutaneous; entfernt; entfernung; entire; entsprechend; entwickelten; entwicklung; epithelial; erfahrungen; erfasst; erfolgte; erfolgte eine; ergab; ergaben; ergebnisse; ergebnisse der; erhielten; erhöhte; erkrankung; ermittelt; ermöglicht; erreichen; erreicht; ersten; erythrozyten; es sich; es wurden; es zu; esophageal; esophagus; established; et-1; evaluation; evaluiert; events; evidence; examination; excellent; excision; experience; experimental; experts; exploration; exposure; expression; extended; extensive; extent; external; extraction; extremität; factors; failed; failure; fall; fanden; fast; fat; feasibility; feasible; fecal; female; female patients; fibers; fibrin; findings; fistel; fistula; fixation; fixierung; flap; flow; flussgeschwindigkeit; fold; follow; foreign; formation; frauen; free; frequent; function; fundoplication; fällen; führten; für; für das; für die; für eine; gain; gallbladder; gastrectomy; gastric; gastroesophageal; gastrointestinal; gegenüber; gender; general; gerd patients; gering; geringer; germany; gesetzlichen; gewebe; giant; gibt; gilt; gist; good; grad; grading; graft; graz; great; group; growth; grundlagen; gruppe; größe; guidelines; gut; gute; haben; half; handelte; harvesting; hat; hatte; hcv; head; healing; healthy; heart; help; hematocrit; hemorrhoidal; hepatectomy; hepatic; her-2; hernia; hernien; heute; hier; high; higher; highest; hind; hinsichtlich; hinweise; hipec; histological; histologisch; histology; histopathological; histopathology; history; ho-1; hohe; hormone; hospital; hours; htx; human; hydrogen; hypertension; hyperthermia; hämatome; häufig; häufiger; häufigsten; höhere; icc; igerd; ihre; iii; ileus; ilk; image; imaging; immer; immunohistochemistry; impact; impaired; implantation; important; improved; improvement; incidence; incision; inclusion; incontinence; increase; independent; index; indikation; induction; infected; infection; infektionen; infiltration; inflammation; inflammatory; influence; inguinal; inhibitor; initial; injury; innerhalb; insbesondere; insgesamt; institution; instruments; insufflation; insulin; integration; intensive; international; intervention; intestinal; intraabdominal; intraoperative; intraperitoneal; intraumbilical; invasive; investigation; involved; involvement; inzidenz; ionm; ipom; ischemia; islet; isolated; isolation; ist; ist bei; ist das; ist der; ist die; ist eine; ist es; ist mit; jahren; january; jedoch; jeweils; jährige; kam; kam es; kann; kaum; kein; keinen; key; kidney; kiefer; kind; klassischen; klinik; klinischen; knochen; kommen; kommt; komplett; komplikationen; konnte; konnte eine; konsekutiven; kontrolle; kurativer; können; laboratory; laparoscopic; laparoskopische; lappenplastiken; large; laryngeal; late; lcn2; lead; leakage; leaks; learning; lebermetastasen; lediglich; left; length; lesions; letzten; levels; life; lihr; like; limb; limited; linken; links; liposarkom; list; literature; little; liver; liver resection; liver surgery; lobes; local; location; lokalen; lokalisation; lokalrezidiv; long; longer; loss; lower; ltx; lvad; lvef; lviv; lymph; lymphknoten; lymphozyten; main; major; males; malignant; mammakarzinoms; management; mandatory; manometry; marker; mass; massive; material; maximal; meals; mean; mean age; measured; mechanical; median; medical; medication; megachannel; mehr; meist; mesenteric; mesh; meshes; mesothelioma; metaplasia; metastases; metastasierten; metastatic; methodik; methods; metrie; mice; microscopy; mild; min; minimal; minor; minuten; mit; mit der; mit einer; mittels; mittlere; model; moderate; monaten; monitoring; months; morbidity; mortality; mri; mrna; mscs; msto; mucosa; multiorgan; multiple; muscle; musste; myocardial; männer; möglich; möglichen; n ¼; n.s; nach; nach der; nach einer; neben; neben der; necessary; neck; necrosis; necrotic; need; negative; neoadjuvant; nephrectomy; nerve; net; netze; neue; neuromonitoring; new; newborns; nicht; noch; node; non; normal; notes; notwendig; novel; november; nsclc; number; nur; oberen; obese patients; obesity; observation; observed; obstruction; oder; oft; ohne; old; onkologischen; onlay; open; operating; operation; operiert; optimal; option; oral; organ; outcome; overall; overexpression; overtube; oxidative; oxygenation; p ¼; pain; palsy; panaritien; pancreas; pancreatic; pancreatitis; parameter; paraplegia; parastomal; partial; patch; patency; pathologische; pathway; patienten; patienten mit; patientinnen; patients; patients background; patients satisfaction; pbmc; pcr; pdr; pediatric; pedicle; percent; percentage; percutaneous; perforation; performance; perfusion; period; perioperative; peripheral; peritoneal; peritonitis; permacol; permanent; persistent; persons; pgd; pgk1; phlegmonen; pigs; placement; plasma; platelet; pleura; pmn; points; polypropylene; poor; population; porcine; portal; position; positive; positive patients; possible; posterior; posters; postoperative; postoperative complications; potential; ppc; preparation; presence; present; pressure; previous; primary; primär; primären; principles; prior; problems; procedure; prognose; prognosis; prognostischer; progression; progrip; prolapse; proliferation; prolonged; promising; prophylaxis; prospective; prosthesis; protein; prothese; protocol; proven; proximal; prt; präoperativ; psp; pth; pts; pulmonary; qol; quality; r ¼; radiation; radical; radikale; radiochemotherapie; radiotherapie; rahmen der; rahmen einer; randomisierten; randomized; range; rapid; rare; rate; rats; ray; reaction; reactive; recent; rechten; rechts; recipients; reconstruction; recovery; recurrence; redo; reduction; reflux; regeneration; region; regurgitation; rektumkarzinom; related; relevant; removal; renal; repair; report; required; rerouting; resected; resection; resistance; response; resultate; results; results background; retrieved; retrospective; review; rezidiv; rezidivrate; right; risikofaktoren; risk; risk patients; robotic; role; routine; routinemäßige; roux; safe; safety; samples; satisfaction; scale; scan; scar; scheint; schlussfolgerungen; schmerzen; scientific; score; screening; sd ¼; sealant; second; secondary; segment; sehen; sehr; sein; seit; selectin; self; seltene; sensory; sepsis; series; serum; setting; severe; severity; shift; shock; short; shorter; shows; sich; sich bei; sich der; sich die; sich eine; sich mit; sie; significant; signifikanten; signs; similar; simultaneous; sind; single; sinnvoll; sinus; sirolimus; site; situation; size; skin; sleeve; small; soi; sollte; somit; sondern; sonographie; sonographisch; sowie; sowie der; sowie eine; sowohl; sowohl die; specific; specimens; spectroscopy; sphincter; spiegel; stadium; stage; standard; standardized; stapled; statistical; statistisch; status; stay; steatosis; stellen; stenosis; stent; sternal; sternotomy; sternum; stimulation; stomach; stones; strahlentherapie; strategies; strategy; strength; stress; structures; studie; study; stunden; subjective; subsequent; successful; sufficient; sulphide; superior; support; suprathel; surface; surgeons; surgery; surgical; surgical treatment; survival; suspect; suture; suturing; swt; sympathetic; symptomatic; symptoms; syndrome; synthetic; system; systemic; systemische; tacrolimus; tagen; targets; tecab; technik; techniken; technique; term; term results; tests; therapeutic; therapeutische; therapie; therapie der; therapie mit; therapie von; therapieverfahren; therapy; thoracic; thoracotomy; thorax; thrombosis; thyroid; tiefen; tiere; time; tissue; tnf; tomography; tool; total; trachea; tract; traf2; transapical; transgastric; transient; transplantation; transplanted; transtar; traten; trauma; treatment; treatment patients; trials; trocar; trotz; trotz der; tube; tumor; tumor cells; tumoren; tumorfrei; tumours; type; ukraine; ulcers; ultraschall; ultrasonography; ultrasound; und; und auf; und bei; und damit; und das; und der; und die; und eine; und es; und ist; und mit; und nach; und postoperative; und therapie; und von; und zur; underlying; underwent; uneventful; unit; university; unknown; unmittelbar; unserer; unter; unterkiefer; unterschied; untersucht; untersuchung; unterzogen; upper; upregulated; upregulation; ureter; urgency; urgent patients; ursache; ursig; use; useful; v.a.c; vacuum; values; valve; variety; vascular; vbg; vegf; vein; ventral; ventricular; verbesserung der; verfahren; vergleich; verlauf; verrucous; verschluss; versorgt; versorgung; verwendet; verwendung; vessels; video; vielen; vienna; viral; visceral; visible; visual; vitb12; vitro; vivo; volume; vom; von; von der; von einer; von patienten; vor; vorgehen; vorliegenden; vorteil; vorteil der; vs.; vsl#3; wall; war; war der; war die; waren; way; weeks; wegen; weight; weiteren; welche; weniger; wenn; werden; werden und; wert; western; wexner; wiederherstellung der; wiesen; wird; wird der; wire; wobei; wochen; women; wound; wrap; wurde; wurde bei; wurde der; wurde eine; wurde mit; wurden die; während; während der; xelox; years; young; younger patients; z.b; zeigen; zeigte; zeigte sich; zeitpunkt; zeitpunkt der; zeitraum; ziel; ziel der; zu einer; zum; zunehmend; zur; zusammenhang; zusätzlich; zwei; zwischen; zwischen der; ¼ n.s; österreichischen; über; über die cache: cord-015369-72cjogxz.txt plain text: cord-015369-72cjogxz.txt item: #43 of 134 id: cord-015389-vwgai4k9 author: None title: Publication only date: 2009-03-25 words: 23906 flesch: 53 summary: Two years overall survival and disease free survival of AML patients were 70% and 67% respectively. The use of this AMD3100 in combination with G-CSF in patients unable to collect adequate CD34+ cells with G-CSF alone was recently reported in 280 patients with lymphoma and multiple myeloma (MM) . keywords: acid; acute; acute gvhd; adequate; adult; advanced; age; alive; allogeneic; allogeneic stem; amd3100; aml; analysis; anemia; anti; aphaeresis; aplastic; asct; atg; atll; autologous; background; bacteria; beam; blood; blood stem; bone; busulfan; cacy; cases; cd34; cell; cell transplantation; center; central; centre; chemotherapy; children; chimerism; chronic; clinical; cml; cmv; collected; combination; complete; complicated; complications; conclusion; conditioning; confi; control; cord; count; course; cryopreservation; csf; cycles; cyclophosphamide; cystatin; dasatinib; data; days; death; defi; dfs; diagnosis; different; disease; dlbcl; dli; donor; dose; early; effect; effective; effi; engraftment; eshap; expansion; experience; factors; failure; female; fever; fludarabine; follow; free; frequent; fungal; grade; graft; gram; group; gvhd; haploidentical; hematologic; hematopoietic; hematopoietic stem; high; higher; hla; hodgkin; hospital; host; hsct; identical; iii; immune; important; improvement; incidence; infection; infl; infusion; intensity; intestinal; introduction; invasive; large; later; leukemia; level; line; liver; long; lymphoma; major; malignancies; marrow; matched; mean; median; median age; median time; medium; melphalan; methods; mismatched; mixed; mobilization; mold; months; mortality; mscs; myeloablative; myeloid; n=1; n=2; negative; neutrophil; nhl; non; normal; number; old; onset; option; order; outcome; overall; partial; patients; pbsc; pcr; period; peripheral; phase; phs; platelets; poor; posaconazole; positive; post; presence; previous; primary; prior; prognosis; progression; prophylaxis; protocol; pst; pts; pulmonary; range; rate; reactivation; recipients; reconstitution; recovery; reduced; refractory; regimen; relapse; related; remission; renal; reported; research; resistant; response; results; risk; rituximab; rst; salvage; second; secondary; sepsis; serum; severe; sibling; signifi; single; skin; source; stage; standard; status; stem; stem cell; steroids; studies; study; successful; survival; symptoms; system; term; therapy; time; total; toxicity; tranexamic; transplantation; treatment; trm; type; umbilical; underwent; unit; university; unrelated; use; values; vivo; weeks; years cache: cord-015389-vwgai4k9.txt plain text: cord-015389-vwgai4k9.txt item: #44 of 134 id: cord-018110-mcw4v13c author: Arnold, Andreas title: Inner Ear date: 2010 words: 15862 flesch: 42 summary: However, recurrence rates of such hearing losses range up to 30%. For profoundly deaf children (typically those with • hearing losses greater than 100 dB) and those chil-loss, the GJB2 gene encodes for the connexin 26 molecule. keywords: acoustic; acute; additional; administration; affected; age; agents; aids; analogue; attacks; attention; audiometry; auditory; autoimmune; available; benign; bilateral; blood; bone; bppv; canal; cases; cause; cells; central; children; chronic; clinical; cochlear; common; complete; complete hearing; conduction; consecutive; contraindications; daily; damage; days; deafness; detailed; development; diagnosis; discrimination; disease; dizziness; dose; drugs; duration; e. g.; early; effects; electrical; endolymphatic; environment; evidence; examination; exposure; external; facial; fig; findings; fistula; fitting; fluctuating; fluid; following; frequencies; frequency; function; gastric; genetic; haemodilutive; haemorheological; hair; head; hearing; hearing aids; hearing impairment; hearing loss; herpes; high; history; hydrops; idiopathic; idiopathic sensorineural; impairment; implantation; important; incidence; infection; infusion; initial; injury; inner; inner ear; intensity; internal; involved; khz; labyrinthitis; language; lesion; level; life; long; longer; malformations; manoeuvre; media; membrane; meningitis; middle; moderate; months; motion; movements; ménière; necessary; nerve; noise; non; normal; nystagmus; otitis; ototoxic; outer; oval; partial; patients; pchi; perilymphatic; period; peripheral; permanent; persistent; possible; prednisolone; presbyacusis; present; problems; processor; profound; profound hearing; prognosis; progressive; progressive hearing; proton; range; rare; receiver; recovery; remission; response; results; rupture; schwannoma; sect; sensorineural hearing; sensory; severe; sickness; signal; sound; special; specific; speech; spontaneous; stage; stimulation; subjective; sudden; surgery; surgical; symptoms; syndrome; system; systemic; term; testing; tests; therapeutic; therapy; thresholds; time; tinnitus; tissue; trauma; treatment; tympanic; use; vertigo; vestibular; vomiting; weeks; window; years cache: cord-018110-mcw4v13c.txt plain text: cord-018110-mcw4v13c.txt item: #45 of 134 id: cord-018239-n7axd9bq author: Rusoke-Dierich, Olaf title: Travel Medicine date: 2018-03-13 words: 8534 flesch: 57 summary: If diarrhoea contains blood or mucus in combination of high fever for more than 2 days, more thorough assessment is required. Severe cases show high fever, neck stiffness, photophobia, headache, disorientation, coma, convulsions, spastic paralysis or death. keywords: abdominal; acute; advice; aedes; affected; africa; age; america; areas; asia; available; bite; blood; cause; children; chronic; common; complications; contact; contaminated; countries; country; cycle; days; deaths; dengue; diagnosis; diarrhoea; different; disease; distribution; diving; dose; effects; eggs; endemic; faeces; failure; fatigue; fever; fluid; following; food; form; headache; high; igm; incubation; infected; infections; initial; like; liver; long; main; malaria; medical; medication; mers; mild; months; mosquitoes; myalgia; nausea; oral; pain; parasite; particular; pathogen; patients; pcr; period; phase; pregnancy; prophylaxis; protection; rabies; regions; reservoir; respiratory; risk; severe; skin; south; specific; symptomatic; symptoms; table; test; therapy; time; travel; treatment; tropical; tuberculosis; vaccination; vaccine; virus; vivax; vomiting; water; weeks; worldwide; wound; years; yellow cache: cord-018239-n7axd9bq.txt plain text: cord-018239-n7axd9bq.txt item: #46 of 134 id: cord-021453-vf8xbaug author: Dysko, Robert C. title: Biology and Diseases of Dogs date: 2007-09-02 words: 42005 flesch: 46 summary: Preventing laboratory animals from contacting ticks is the primary means to avoid monocytic ehrlichiosis in research dogs. For this reason, medical treatment of heartworm disease is not usually attempted in research dogs. keywords: abdominal; ability; abnormalities; acid; acral; acute; addition; adequate; administration; adult; affected; age; agents; aggressive; allergy; ammonia; anemia; angarano; animals; anorexia; antibiotic; antibody; appearance; areas; artery; ascarid; aspiration; associated; asymptomatic; atrophy; available; bacterial; beagles; behavior; benign; best; biomedical; biopsy; bitch; bite; blood; body; bone; bordetella; bph; breed; breeding; bronchiseptica; burn; canine; caninum; canis; cardiovascular; care; cases; cataracts; catheter; cats; cause; cavity; cells; changes; characteristic; chlorhexidine; choice; chronic; clean; clinical; clinical signs; closure; colony; common; complete; complications; condition; congenital; contact; contagious; contaminated; control; corneal; cough; culture; cycle; cysts; days; death; decrease; deficiency; definitive; demodicosis; dermatitis; development; diagnosis; diarrhea; diet; dietary; differential; differential diagnosis; difficult; direct; discharge; discomfort; discussion; disease; disorder; distemper; dogs; drug; dysplasia; early; edema; effective; effects; eggs; ehrlichia; ehrlichiosis; elbow; encephalopathy; endothelial; energy; enlarged; entire; environment; epithelial; epizootiology; essential; estrogen; estrus; et al; etiology; examination; excision; exercise; experimental; exposure; extensive; external; eye; facilities; facility; factors; failure; fat; fatty; fecal; feces; female; fenbendazole; ferguson; fever; fibers; fig; findings; flea; fluid; food; form; free; function; fungal; gastric; gastrointestinal; generalized; giardia; gland; good; grade; gram; granuloma; greene; gross; group; growth; hair; healing; health; heartworm; helicobacter; hemorrhages; hepatic; high; hip; histiocytomas; histopathologic; history; hormone; host; hours; human; hygromas; hyperplasia; hypothyroidism; identification; iii; illness; immune; immunologic; important; incidence; increase; indicative; individuals; indwelling; infected; infection; infective; infestations; inflammation; inflammatory; information; ingestion; initial; injury; intake; interdigital; intermediate; internal; intestinal; jejuni; joint; juvenile; kennel; laboratory; large; larvae; lens; leptospirosis; lesions; lethargy; levels; lewis; lice; lick; life; likely; liver; local; long; loss; low; lower; lung; lyme; lymphocytic; lymphoma; macewen; male; malignant; mammary; management; masses; mast; means; medicine; membranes; metabolism; metastasis; migration; mild; minimal; months; mucosa; mucous; muller; multiple; muscle; necessary; necrosis; need; negative; neoplasia; neurologic; new; nodes; normal; number; obesity; onset; oral; order; organism; pain; panciera; paralysis; parturition; parvovirus; pathogenesis; pathologic; period; peterson; phase; placement; platys; pneumonia; poor; population; positive; possibility; possible; potential; practice; presence; present; pressure; prevention; primary; problem; production; proper; prostatic; protein; protocols; pulmonary; puppies; pups; purpose; rabies; random; range; rapid; rate; red; removal; renal; reported; reproductive; requirements; research; research complications; research dogs; research setting; respiratory; response; result; right; risk; role; samples; secondary; section; self; semen; sensitivity; sepsis; serum; setting; severe; severity; significant; signs; similar; site; size; skin; small; soft; solution; source; source dogs; species; specific; spp; spread; stage; states; studies; study; subclinical; subcutaneous; superficial; supplementation; supportive; surface; surgery; surgical; swaim; swelling; syndrome; systemic; systems; techniques; temperature; term; tests; textbook; therapy; thrombocytopenia; tick; time; tissue; topical; total; tracheobronchitis; tract; transmissible; transmission; trauma; treatment; trevor; tsh; tumors; type; ulcers; united; unknown; use; uterine; vaccination; vaginal; variable; vascular; vasculitis; vector; venereal; veterinary; viral; virus; volume; vomiting; vulva; waldron; water; weeks; weight; whipworm; wide; worms; wound; years; young cache: cord-021453-vf8xbaug.txt plain text: cord-021453-vf8xbaug.txt item: #47 of 134 id: cord-021555-rrverrsj author: Delano, Margaret L. title: Biology and Diseases of Ruminants: Sheep, Goats, and Cattle date: 2007-09-02 words: 71795 flesch: 48 summary: In less severe outbreaks or individual animal disease, definitive diagnosis may never be made. Therefore, they should be housed in groups or at least within eyesight and hearing of other animals. keywords: abdomen; abdominal; abnormalities; abomasal; aborted; abortion; abscesses; acid; acidosis; acute; addition; adequate; administration; adult; adult animals; affected; affected animals; age; agents; agricultural; amounts; anaerobic; anemia; animals; anorexia; antibiotics; antibodies; antibody; appropriate; arcanobacterium; areas; arthritis; artificial; associated; asymptomatic; ataxia; available; bacterial; base; beef; behavior; best; beta; birth; birthing; biting; black disease; bladder; bloat; blood; bloodstream; bluetongue; blv; body; bovine; bovis; brain; breeding; breeds; brown; brucella; brucellosis; bulls; bvdv; caev; calcium; calf; calves; campylobacter; caprine; cardiac; care; carriers; caseous; cases; cattle; causative; cause; cells; central; changes; characteristic; chlamydia; chronic; cleaning; clinical disease; clinical signs; clostridial; cold; coli; colostrum; commercial; common; comparable; complex; complications; concentrates; concurrent; condition; congenital; conjunctivitis; contact; contagious; contagious disease; contaminated; contamination; contrast; control; copper; cord; corneal; coronavirus; corynebacterium; course; cows; culture; culturing; cycle; dairy; dairy cattle; damage; dams; dark; days; dead; death; decrease; defects; deficiency; definitive; degeneration; dehydration; dependent; depressed; depression; dermatitis; detection; development; diagnosis; diarrhea; diet; dietary; differential; differential diagnosis; difficult; direct; discharges; disease; disease signs; disease virus; display; docking; doe; domestic; dose; dry; duration; early; ecthyma; edema; effective; effects; eggs; electrolyte; elevated; elisa; embryo; encephalitis; endemic; energy; enlargement; enterotoxemia; environment; enzootic; enzyme; epithelial; epizootiology; equipment; erosions; escherichia; essential; estrus; etiology; evidence; evident; ewes; example; excessive; experimental; exposure; external; facilities; facility; factors; failure; fall; family; farm; fatty; feces; fed; feed; feeding; feedstuffs; feet; female; fetal; fetuses; fever; findings; flies; flock; fluids; following; food; foot; form; formation; free; fusobacterium; gastrointestinal; generalized; genetic; gestation; gland; glucose; goats; good; gray; gross; group; growth; hair; handlers; handling; hay; head; health; heat; heifers; helpful; hemoglobinuria; hemolysis; hemolytic; hemorrhage; hepatic; herd; herpesvirus; high; holstein; hoof; host; housing; humans; hyperplasia; hyperthermia; hypocalcemia; identification; iii; illness; immune; immunity; important; inability; incidence; increase; incubation; individual; induced; industry; infected; infected animals; infection; inflammation; inflammatory; ingested; ingestion; initial; injuries; injury; insemination; intact; intake; interdigital; intermediate; internal; intestines; introduction; involved; isolated; isolation; johne; joints; kids; known; laboratory; lack; lambs; lameness; large; larvae; lead; length; leptospirosis; lesions; levels; lice; life; light; likely; limiting; listeria; liver; livestock; local; long; longer; loss; low; lungs; lymph; lymphadenopathy; lymphosarcoma; major; male; malignant; mammary; management; manifestations; mastitis; materials; maternal; mature; means; measures; medicine; membranes; mesenteric; metabolic; methods; migration; mild; milk; milking; models; modified; monitoring; months; morbidity; mortality; mouth; mouth disease; mucosa; mucous; multiple; muscle; muscular; mycobacterium; mycoplasma; nasal; natural; navel; necessary; neck; necrophorum; necropsy; necropsy findings; necrosis; necrotic; negative; nematodes; neonatal; neonates; neospora; nervous; new; newborn; nodes; non; nonmotile; normal; novyi; number; nursing; nutrition; ocular; older; older animals; oocysts; oral; organism; organs; outbreaks; oxytetracycline; pain; painful; palpation; paralysis; parasites; particular; parturition; passive; pasteurella; pasture; pathogenesis; pathogens; penicillin; pens; perfringens; period; persistent; photosensitization; placental; placentitis; pneumonia; poisoning; polyarthritis; poor; positive; possible; potential; practices; pregnancy; pregnant; presence; present; presentation; prevention; primary; problems; procedures; process; produce; production; products; prognosis; programs; progressive; prolapse; prolonged; proper; protein; pruritus; pseudotuberculosis; pulmonary; quality; rabies; range; rapid; rare; rates; reach; recent; recovery; rectal; red; regimens; related; removal; replacers; reportable; reproductive; requirements; research; research animals; reservoirs; resistant; respiratory; respiratory disease; response; rest; result; rhinotracheitis; risk; role; rotavirus; roughage; rumen; ruminal; ruminants; salmonella; sanitation; scrapie; screening; season; secondary; secretions; section; selenium; semen; sensitive; septicemia; serological; serology; serotypes; serum; severe; shedding; sheep; sherman; shipping; short; similar; single; size; skin; small; smaller; smears; smith; sodium; soil; solutions; sources; species; specific; spinal; sporadic; spore; spp; spread; spring; stage; standard; staphylococcus; states; stomach; stomatitis; strains; stress; stresses; subclinical; subcutaneous; subsequent; successful; sudden; sufficient; sulfate; supportive; surface; surgical; susceptible; swelling; swine; swollen; syndrome; system; systemic; tail; techniques; temperature; term; testing; tests; tetanus; therapy; ticks; time; tissues; toxemia; toxicity; toxin; toxoplasma; tract; transfer; transmission; trauma; treatment; trimester; tube; type; typical; udder; ulceration; ulcers; umbilicus; united; unthriftiness; urethral; urine; useful; uterine; uterus; vaccinated; vaccination; vaccine; vaginal; vectors; vesicles; vesicular; veterinary; viral; virus; vitamin; vulva; vulvovaginitis; wall; warm; warts; water; weak; weakness; weaning; weeks; weight; western; white; wild; winter; wool; worldwide; worms; wounds; years; yellow; young; young animals; younger; zinc; zoonotic cache: cord-021555-rrverrsj.txt plain text: cord-021555-rrverrsj.txt item: #48 of 134 id: cord-022659-chwk2bs4 author: None title: Abstracts: Poster session date: 2004-10-08 words: 49293 flesch: 47 summary: We conclude that this cingulate activation may reflect the greater involvement of an attentional network (of which the anterior cingulate is a part) in tasks requiring a higher degree of mental work on the part of AD patients. To investigate erythrocyte membrane molecular dynamics in AD patients and age-matched controls, we investigated erythrocyte membrane molecular motion at the surface (fluorescamine), aqueous-hydrocarbon interface (DPPE-ANS), and hydrocarbon core (1219j-AS; PPC-DPH) by steady-state fluorescence anisotropy measurements of 16 probable AD patients (5 males; 11 females) and 20 (1 1 males; 9 females) age-matched controls. keywords: .05; ability; abnormal; abnormalities; abnormality; absent; abstracts; accumulation; acid; activation; active; activities; activity; acute; ad patients; addition; admission; adult; affected; age; aged; agent; aging; als; alterations; alzheimer; american; amino; amplitude; amyotrophic; analysis; animals; ann; anterior; antibodies; antibody; antigen; aphasia; app; areas; arm; artery; assay; assessment; associated; association; astrocytes; atrophy; attentional; autoimmune; autopsy; autosomal; average; basal; basic; battery; behavioral; bilateral; binding; biopsy; blind; block; blood; brain; brainstem; breast; ca2; calcium; canada; cancer; cases; cause; cells; central; cerebellar; cerebral; cerebrospinal; cervical; chain; changes; chorea; chronic; class; clinical; clones; cns; cognitive; combined; common; community; complete; complex; concentrations; conditions; conduction; consecutive; consistent; content; contralateral; contrast; controls; cord; correlation; cortex; cortical; course; cranial; criteria; cross; csf; culture; cyclophosphamide; daily; damage; data; days; death; decline; decreased; deficits; definite; degeneration; degree; demented; dementia; denervation; dependence; deprenyl; detectable; development; diagnosis; differences; different; differentiation; disability; disease; disorders; distal; distinct; distribution; dna; dominant; dopa; dopamine; dorsal; dose; double; drug; dss; duration; dysfunction; dyskinesia; dystonia; dystrophy; eae; earlier; early; education; effective; effects; elderly; electrophysiological; elevated; emg; emission; endothelial; enhancement; enzyme; epidemiological; etiology; evaluation; evidence; evoked; examination; experimental; expressed; expression; extent; extremity; eye; factors; families; family; fatigue; features; females; fibers; findings; flow; fluid; focal; following; free; frequency; frequent; frontal; function; gait; ganglia; gbs; gender; generalized; genetic; glutamate; gm1; good; grade; grammatical; greater; group; growth; hand; head; healthy; hemisphere; high; higher; hippocampus; histological; history; hla; holiday; hours; htlv; human; hypothesis; ibm; ifnp; igg; images; immune; immunoglobulin; immunological; impaired; impairment; important; improved; improvement; incidence; incontinence; increase; independent; index; individuals; induced; infarct; infected; infection; inflammation; inflammatory; information; inhibition; initial; injury; intracranial; intravenous; involved; involvement; ipsilateral; iron; ischemic; ivig; japan; jews; laboratory; lacunar; language; large; latency; later; lateral; lead; left; lesions; levels; levodopa; like; limbs; line; living; long; longer; loss; lower; lyme; lymphocytes; lymphoma; macrophages; magnetic; major; males; marked; mashadi; matter; maximum; mbp; mean; measured; measurements; mechanism; median; members; membrane; memory; mental; metabolism; method; methylprednisolone; mhc; mice; microglia; microscopy; midline; migraine; migraine patients; mild; mini; mitochondrial; mms; model; moderate; molecular; molecules; monoclonal; months; morphine; motor; mouse; movements; mri; multiple; murine; muscle; myelin; myopathy; n =; naming; negative; neglect; nerve; nervous; neural; neurological; neuron; neuronal; neuropathy; neuropsychological; new; nmr; nondemented; normal; number; objective; observations; observed; old; onset; opca; operation; opsoclonus; oral; overall; p =; pain; parameters; paraparesis; parkinson; parkinsonism; partial; pathogenesis; pathological; pathways; patients; pattern; pcr; pd patients; pdc; pdgf; percent; performance; period; peripheral; pet; phase; placebo; plaques; plasma; point; polymerase; polyneuropathy; population; positive; positron; possible; posterior; postmortem; potential; presence; present; pressure; presumed; prevalence; previous; primary; prior; probable; probe; problems; processes; program; progressive; protein; psp; pts; pulse; pure; purified; quantitative; range; rapid; rate; rating; rats; rcbf; reaction; receptor; records; recovery; reduction; regional; regions; regression; related; relationship; release; reliable; repetitive; report; response; rest; results; right; risk; rochester; role; rrf; samples; scale; scans; sclerosis; scopolamine; scores; screening; second; secondary; sections; selective; sensitive; sensory; sequence; serial; series; serum; severe; severity; sex; sgpg; short; signal; significant; signs; sihi; silicone; similar; single; sites; size; skin; small; space; spastic; specific; specimens; spinal; stable; staining; standard; state; status; stimulation; strength; stress; stroke; studies; study; subjects; subsequent; support; surface; survival; symptomatic; symptoms; syndrome; system; systemic; tasks; techniques; temporal; term; test; testing; therapeutic; therapy; thought; time; tissue; total; toxicity; toxin; transient; transport; treatment; tremor; trials; tumor; type; typical; unchanged; unified; unique; unknown; untreated; updrs; upper; uptake; urinary; useful; variability; variable; variance; vascular; verbal; viral; virus; visual; volume; weakness; weeks; western; white; women; years; york cache: cord-022659-chwk2bs4.txt plain text: cord-022659-chwk2bs4.txt item: #49 of 134 id: cord-023017-k6edtg58 author: None title: AASLD Abstracts (pp. 282A–382A) date: 2006-02-10 words: 65964 flesch: 47 summary: The aim of the present study was to investigate if the same inhibition takes place in livers cells of patients with chronic hepatitis C. From February 2001 to April 2002, all patients with chronic hepatitis C referred to the outpatient liver clinic of the University Hospital Basel were asked for their permission to use part of the liver biopsy for this study. Increased T cell activation with Eta may also suggest that TNFA suppress T cell function and may contribute to refractoriness to INF therapy in HCV patients. keywords: -no; aa patients; ability; absence; acid; actin; activated; activation; active; activity; acute; addition; adenosyl; adiponectin; administration; adulis; adult; adult liver; adverse; african; age; aim; aims; albumin; alcoholic; alfa-2a; alpha; alt; amino; aminotransferase; analysis; animals; anti; antibodies; antibody; antigen; antiviral; apoptosis; area; arm; ascites; assay; associated; association; available; average; background; baseline; bdl; beginning; beta; better; bile; biliary; bilirubin; binding; biochemical; biopsies; biopsy; bleeding; blood; blot; bm cells; bmcs; bmi; body; bone; c virus; calculated; canalicular; cancer; capacity; cases; cause; cc14; cd34; cd4; cd8; cdna; cell responses; cells; cellular; center; chain; changes; characteristics; chromosome; chronic; chronic hcv; chronic hepatitis; chronic liver; cifn; circulating; cirrhosis; cirrhotic; cirrhotic patients; clearance; clinical; clones; cmv; cohort; collagen; combination; combination therapy; common; comparison; complete; complexity; concentration; conclusions; conditions; consistent; content; continued; contrast; control; core; correlation; corresponding; count; course; crg; criteria; ctgf; culture; current; cyanoacrylate; cytokeratin; cytokines; cytometry; daily; damaged; data; date; days; dcs; death; decrease; degree; dendritic; dendritic cells; dependent; detectable; determined; development; diagnosis; diet; differences; different; differentiation; direct; disclosures; discontinuation; disease; distribution; dna; donor; dose; dosing; drug; ducts; duration; dysfunction; early; effect; effective; efficacy; element; elevated; elisa; elispot; end; endogenous; energy; enzyme; epithelial; es cells; esld; ethanol; events; evidence; experiments; expression; factors; failure; fatty; fed; female; fetal; fibroblasts; fibrogenesis; fibrosis; fibrotic; findings; flow; fluorescence; fold; following; form; france; free; frequency; function; fxr; gal; gamma; gel; gender; gene; gene expression; general; genome; genotype; gfp; good; grade; graft; greater; group; growth; haart; half; hcc; hcv; hcv core; hcv genotype; hcv infection; hcv patients; hcv proteins; hcv replication; hcv rna; hcv therapy; hcv viral; healthy; hemodynamic; hepatic; hepatic fibrosis; hepatitis; hepatitis patients; hepatoblasts; hepatocellular; hepatocytes; hepg2; higher; histological; histology; hiv; homa; hours; hrql; hrs; hsc; hscs; human; human liver; hypertension; hypothesis; ifn; ifn therapy; il-18; immune; immunohistochemistry; immunosuppression; impaired; important; improved; improvement; incidence; increased; index; individual; induced; induction; infected; infected patients; infection; inflammation; infusion; inhibitor; initial; initiation; injury; insulin; intake; interferon; intracellular; intrahepatic; introduction; involved; ir1; ishak; isis; isolated; israel; japan; key; kinase; kit; klf6; large; later; length; levels; lfa-1; ligands; like; likely; limit; lineage; linear; lines; lipid; little; liver; liver biopsies; liver biopsy; liver cells; liver disease; liver failure; liver fibrosis; liver injury; liver specific; liver transplantation; load; long; loss; lower; ltx; major; majority; male; marked; markers; marrow; mass; matrix; mdc; mean; mechanism; median; medical; medium; meld; membrane; metabolic; methionine; methods; mglkg; micalb; mice; microarray; microscopy; migration; mild; mitochondrial; model; moderate; molecular; mononuclear; mononuclear cells; monotherapy; months; mouse; mrna; mrp2; muscle; mutations; mxa; naive; napi; necrosis; negative; new; non; normal; northern; novel; ns3; ns5a; ntpdase2; number; o.ool; oatp8; olt; order; organ; outcome; oval; oval cells; overall; oxidative; p =; p<0.05; parameters; parenchymal; partial; pathogenesis; patients; pbmc; pcr; pdc; peak; peg; peginterferon; pegylated; peptide; period; peripheral; persistence; phase; phenotype; plasma; plasmacytoid; platelet; point; polymerase; pools; population; portal; positive; positive cells; positive patients; possible; post; potential; ppar; presence; present; pressure; prevalence; previous; primary; prior; probability; progression; proliferation; promoter; properties; prophylaxis; prospective; protease; protein; protein expression; protocol; quantitative; racial; randomized; range; rat liver; rate; rats; rbv; real; receptor; recipients; recombinant; recurrence; reduction; regeneration; regulated; regulation; rejection; relationships; relative; release; replication; replicon; report; resistance; resolved; respect; responders; response; responsible; results; reverse; ribavirin; rifampicin; risk; role; safety; samples; sarcoidosis; scores; screening; second; self; sequences; serum; serum hcv; severe; severity; sf-36; signal; signaling; significant; similar; single; site; situ; sla; small; smooth; social; socs-1; sp cells; specific; spleen; splenocytes; spontaneously; stage; staining; standard; steatosis; stellate; stellate cells; stem; stem cells; steroids; stimulated; stimulation; stress; strong; studies; study; subjects; support; suppository; surface; survival; sustained; svr; symptoms; system; t cells; taa; table; tacrolimus; targeting; test; tgf; therapeutic; therapy; thl; time; tips; tissue; titer; tolerability; total; transcription; transgenic; transplant patients; transplantation; transplanted; transport; treated; treatment; trial; ttg; ttr; tumor; undifferentiated; unit; university; untreated; uptake; urea; use; values; variability; varices; vein; viral; viral response; virological; virus; vitro; vivo; weekly; weeks; weight; western; wild; years cache: cord-023017-k6edtg58.txt plain text: cord-023017-k6edtg58.txt item: #50 of 134 id: cord-023095-4dannjjm author: None title: Research Abstract Program of the 2011 ACVIM Forum Denver, Colorado, June 15–18, 2011 date: 2011-05-03 words: 134382 flesch: 49 summary: Mminimum HR, mean HR and the HRV variables (7 and 10) differing between dog groups, also consistently decreased with increasing MR, LA/Ao and the proximal isovelocity surface area in CKCS. The apparently normal levels of hexosaminidase A activity in affected dog samples may be a result of b subunit overexpression. keywords: 5ht; 95%ci; abdominal; abnormalities; absence; absorption; abstract; abundance; access; accumulation; accuracy; accurate; acetate; acid; acth; activation; active; activity; acute; additional; adequate; adhesion; administration; admission; adrenal; adult; adult cats; adult dogs; adverse; affected dogs; age; aged; agents; aggregation; aim; aims; airway; aki; albumin; aldosterone; alpaca; alpha; alterations; alveolar; ambulatory; amino; analysis; analyzer; anaplasma; anemia; anesthesia; anesthetized; animals; anova; antibodies; antibody; antigen; antimicrobial; aortic; apparent; approach; appropriate; area; arterial; articular; arvc; aspiration; aspirin; assay; assessment; associated; association; asymptomatic; atenolol; atrial; attempts; auc; automated; available; average; avp; axis; azotemia; bacterial; balf; bartonella; basal; baseline; basis; bcs; beagle dogs; beagles; beginning; benazepril; beta; better; binding; biochemical; biomarkers; biopsies; biopsy; bleeding; blinded; blood; blood glucose; blood samples; blot; body; bone; bovine; bowel; boxers; bpm; brain; breed dogs; breeds; calcitriol; calcium; calculated; calprotectin; calves; canal; cancer; canine; canis; carboplatin; cardiac; cardiomyopathy; care; cartilage; cases; catheter; cats; cattle; caudal; cause; cbc; cca; ccp; cdv; cell; cellular; center; central; cerebellar; cervical; chain; challenge; changes; characteristics; characterized; chemistry; chf; chf cats; chromatography; chronic; ciprofloxacin; ckcs; ckd; classes; classified; clearance; client; clinical; clinical disease; clinical signs; clinicians; clinicopathologic; clinics; clm; clopidogrel; clostridium; cns; coagulation; cobalamin; coefficient; coli; collagen; collapse; collection; college; colon; colostrum; combination; commercial; common; compare; comparison; complete; completion; composition; compression; computed; concentrations; conclusion; concurrent; condition; confidence; confirmed; congenital; congestive; consecutive; consistent; content; contrast; control cats; control dogs; control group; control horses; control study; controls; copper; correlated; correlation; cortisol; count; course; cpe; cpr; cpv; cranial; creatinine; cria; criteria; cross; crossover; crp; cryptosporidium; csf; ctni; culture; curve; cutoff; cyclophosphamide; cyclosporine; cystine; cytokine; cytometry; daily; damage; data; date; days; dca; death; decreased; defect; deficiency; definitive; degenerative; degree; deletion; density; dependent; described; design; detection; determination; determined; development; deviation; device; dexamethasone; diabetes; diabetic; diagnosis; diarrhea; diastolic; diet; dietary; differences; different; difficile; difficult; digital; diminazene; direct; discharge; disease; disease cats; disorders; dissolution; distribution; dmvd; dna; documented; dogs; dogs o; domperidone; donkeys; doppler; dorsal; dose; dosing; double; doxycycline; drug; dry; duodenal; duodenum; duration; dysfunction; early; ecg; echocardiographic; edema; edta; effective; effects; efficacy; effusion; ehrlichia; elevated; elisa; end; endothelial; energy; enlargement; enrofloxacin; enteric; enzyme; epithelial; equal; equine; equivalent; erythrocytosis; established; estradiol; eus; euthanasia; evaluated; evaluation; events; evidence; exact; examination; exercise; experimental; exposure; expression; factors; faecalibacterium; failure; farms; fasting; fatty; features; fecal; fecal samples; feces; fed; feeding; feline; female dogs; females; fever; fgf-23; fibrinogen; fibrosis; field; final; findings; firocoxib; fiv; flagellin; flow; fluid; fna; foals; fold; following; food; formalin; formulation; fossa; fraction; frd; free; frequency; frozen; function; furosemide; future; gastric; gastrointestinal; gastrointestinal disease; gemcitabine; gender; gene; general; generation; genetic; genome; genomic; gentamicin; german; gfr; giardia; gingivitis; glucocorticoids; glucose; glut12; goal; golden; good; grade; greater; group; growth; gsd; gsh; hac; half; hand; hbgm; hcm; head; healthy cats; healthy dogs; healthy horses; heart; heart disease; help; hepatic; herda; hereditary; herniation; het dogs; higher; highest; histopathological; histopathology; history; homozygous; hormone; horses; hospital; hospitalization; hours; hplc; hrs; hrv; hsa; hsp; human; humerus; hyperthyroid; hyperthyroid cats; hypothesis; hypothyroidism; iad; ibd; identical; identification; idiopathic; ifn; igg; iii; il-10; il-2; il-4; il-6; il-8; iliac; ill; ill dogs; illness; images; imaging; immune; impact; impaired; impedance; important; improved; improvement; incidence; increase; index; indirect; individual; induced; induction; infected; infected dogs; infection; inflammation; inflammatory; influence; information; ingestion; inhibitor; initial; injury; insertion; insulin; intact; interaction; interest; internal; interstitial; intervals; intervertebral; intracellularis; intravenous; invasive; investigation; iodine; ipf; irc; iris; iron; isolates; ivabradine; kidney; kinase; kit; knowledge; kruskal; laboratories; laboratory; lack; lactate; lameness; laminar; laminitis; large; lateral; left; length; lesions; leukocytes; levels; life; likely; limb; limited; linear; lines; lipid; liquid; little; liver; location; logistic; long; longer; loss; lower; lps; lung; lymphocyte; lymphoma; maintenance; major; majority; males; mammary; management; mann; manual; mapk; marcks; marker; marrow; mass; matter; maximum; mdr; meal; mean; mean ae; measured; measurements; mechanisms; median; medical; medicine; membrane; meningiomas; meq; metabolic; methimazole; method; microbiota; mii; mild; minimal; minimum; minutes; mitral; mixed; mmhg; mmol; mmvd; model; moderate; molecular; molecules; monitoring; months; mortality; mri; mrna; mucosal; multiple; muscle; mutant; mutation; mycoplasma; myocardial; necessary; needle; negative; neoplasia; neurological; neutrophils; new; nmol; non; normal cats; normal dogs; normal horses; novel; number; obese dogs; obesity; objective; observed; obstruction; occurrence; occurring; og1; old; omeprazole; onset; oral; organisms; osa; outcome; ovariectomy; overall; overweight; owners; oxygen; p o; p38; pain; pancreas; pancreatic; parameters; partial; participants; partum; pathogenesis; pathogens; pathway; patients; pattern; pcr; pda; peak; peis; people; peptide; percentage; performance; perfringens; period; peripheral; persistent; pet; phagocytophilum; pharmacokinetic; phase; phosphate; phosphorylation; physical; pigs; piiinp; pilot study; placebo; placement; plasma; plasma concentrations; plasma samples; platelet; ple dogs; pln; plus; pmol; point; polymerase; polymorphisms; ponies; pooled; poor; population; positive; possible; post; potential; ppf; ppid; ppm; practices; predictive; preliminary; preparation; presence; present; present study; presentation; pressure; prevalence; previous; primary; prior; problem; probnp; procedure; processes; production; profile; prognosis; proliferation; proportion; prospective; protein; protocol; proximal; psva; pulmonary; puppies; purpose; qpcr; quality; quantitative; quarter; racing; radiographic; randomized; range; ranitidine; rank; rao; rapid; rare; rate; ratios; rbc; reaction; recent; receptor; recorded; records; recovery; rectal; reduced; reference; region; regional; regression; regurgitation; related; relationship; relative; release; relevant; remaining; remission; renal; reported; reports; research; resistance; resolution; respiratory; respondents; response; results; retriever; retrospective; retrospective study; reverse; right; risk; role; rottweilers; routine; safety; saline; salmonella; samples; sampling; sas; sba; scale; scan; score; screening; sd dogs; sdr; secondary; secretion; sedation; segment; sensitive; sensitivity; sepsis; septic; sequence; sequencing; serum; serum concentrations; serum samples; set; severe; severity; sex; shar; shedding; short; shorter; sid; signaling; signalment; significant; significant difference; signs; similar; simple; single; site; size; skin; small; small dogs; smooth; snps; sodium; software; spayed; spearman; species; specific; specificity; specimens; spinal; spontaneous; spp; square; stability; stable; stage; staining; stalls; standard; standardized; starting; statistical; status; sternal; stimulated; stimulation; stomach; strain; stress; striatin; strong; structural; struvite; student; studies; study; study period; study population; subsequent; successful; suggested; sum; supplementation; support; surface; surgery; surgical; survival; susceptibility; susceptible; syndrome; synovial; syrinx; system; systemic; systolic; tablets; target; tcc; teaching; technique; teg; temperature; terminal; terriers; test; testing; tetracycline; therapeutic; therapies; therapy; thickness; thoracic; thrombocytopenia; tick; time; tissue; titers; tlr5; tolerance; tool; total; toxicity; toxin; tract; traditional; transfusion; transport; trauma; treatment; treatment group; trilostane; tt4; tubes; tumor; type; ultrasound; underlying; underwent; university; unknown; untreated; upc; upper; uptake; urea; urinalysis; urinary; urine; uroliths; use; useful; utility; vaccinated; vaccination; vaccine; values; valve; variability; variables; variation; variety; vascular; ventricular; veress; veterinary; vhs; viral; virus; visceral; vitamin; vitro; vivo; volume; vomiting; wall; wallis; water; weekly; weeks; weight; western; white; whitney; wide; widely; wilcoxon; wild; wnt; work; wound; years; zinc; zooepidemicus cache: cord-023095-4dannjjm.txt plain text: cord-023095-4dannjjm.txt item: #51 of 134 id: cord-023100-0pqnsiid author: None title: Abstract date: 2008-04-10 words: 245 flesch: 50 summary: Specific anti-ccv IgM was first detected in plasma three days after inoculation and IgG on days 4 to 7. Small amounts of anti-ccv IgG, IgM and IgA were detected in duodenal secretions, but none in bile. keywords: ccv; days; inoculation; small; virus cache: cord-023100-0pqnsiid.txt plain text: cord-023100-0pqnsiid.txt item: #52 of 134 id: cord-027259-f4sgobcz author: Metsker, Oleg title: Stroke ICU Patient Mortality Day Prediction date: 2020-05-23 words: 5336 flesch: 38 summary: According to the findings of a large-scale study of recent years, some modern epidemiological trends have been identified [3] : In general, global statistics show a decline in stroke mortality over the past two decades due to the introduction of new treatments (thrombolysis, thrombectrosis), but the absolute number of people who have stroke is only increasing every year The unmodifiable factors of stroke mortality include: gender, age, type of stroke, localization of lesion. keywords: acute; age; analysis; atrial; atrophy; blood; brain; care; center; cerebral; characteristics; clinical; combination; comorbidity; data; days; death; development; difference; disease; early; factors; features; fibrillation; following; forest; general; global; hemorrhagic; high; hospital; hospital mortality; index; interpretation; ischemic; ischemic stroke; large; learning; lesion; lethal; machine; medical; methods; models; mortality; mortality rate; national; number; patients; predictors; presence; pressure; prognostic; random; rate; registry; results; risk; scales; significant; stroke; stroke mortality; stroke patients; study; subgroups; system; time; treatment; type; unit; urine; value; volume; years cache: cord-027259-f4sgobcz.txt plain text: cord-027259-f4sgobcz.txt item: #53 of 134 id: cord-027811-vk3qnumx author: Freedberg, Daniel E. title: Impact of Fiber-Based Enteral Nutrition on the Gut Microbiome of ICU Patients Receiving Broad-Spectrum Antibiotics: A Randomized Pilot Trial date: 2020-06-11 words: 3843 flesch: 45 summary: Enteral fiber was associated with nonsignificant trends toward increased relative abundance of short-chain fatty acid–producing bacteria and increased short-chain fatty acid levels among ICU patients receiving broad-spectrum IV antibiotics. All observations were intent-totreat and there was a 20% rate of crossover, a common challenge for ICU nutrition studies (19) . keywords: abundance; acid; antibiotics; bacteria; baseline; broad; care; chain; change; colonization; content; data; day; days; differences; digital; effects; enteral; fatty; fecal; fiber; fig; group; gut; icu; infection; intake; interquartile; iqr; levels; median; microbiota; nutrition; outcome; patients; producers; producing; randomized; range; rectal; relative; scfa; short; significant; size; spectrum; stool; studies; study; supplemental; supplementation; swabs; test; trial cache: cord-027811-vk3qnumx.txt plain text: cord-027811-vk3qnumx.txt item: #54 of 134 id: cord-029112-u507i0t0 author: Smith, Keisha title: A Phase 3 Open-label, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Intravenously Administered Ravulizumab Compared with Best Supportive Care in Patients with COVID-19 Severe Pneumonia, Acute Lung Injury, or Acute Respiratory Distress Syndrome: A structured summary of a study protocol for a randomised controlled trial date: 2020-07-13 words: 20949 flesch: 39 summary: While the Investigator is not obligated to actively seek this information in former study patients, he or she may learn of an SAE through spontaneous reporting. key: cord-029112-u507i0t0 authors: Smith, Keisha; Pace, Amy; Ortiz, Stephan; Kazani, Shamsah; Rottinghaus, Scott title: A Phase 3 Open-label, Randomized, Controlled Study to Evaluate the Efficacy and Safety of Intravenously Administered Ravulizumab Compared with Best Supportive Care in Patients with COVID-19 Severe Pneumonia, Acute Lung Injury, or Acute Respiratory Distress Syndrome: A structured summary of a study protocol for a randomised controlled trial date: 2020-07-13 journal: Trials DOI: 10.1186/s13063-020-04548-z sha: doc_id: 29112 cord_uid: u507i0t0 OBJECTIVES: keywords: acceptable; activation; acute; additional; administration; aes; age; alexion; alternative; alxn1210; amendment; analyses; antibodies; applicable; appropriate; ards; assessment; associated; available; baseline; best; blood; bsc; care; case; change; clinical; clinical study; complement; confirmed; consent; contraception; coronavirus; cov-305; covid-19; criteria; data; date; day; days; designee; disease; documents; dose; drug; duration; ecrf; effect; effective; efficacy; endpoint; evaluation; event; exclusion; expected; factor; failure; female; female patients; final; fio2; following; free; global; group; health; hospitalization; hours; iec; immunogenicity; incidence; inclusion; infection; inflammatory; information; informed; infusion; inhibition; injury; intervention; investigational; investigator; irb; jun; laboratory; life; local; lung; mechanical; medical; medications; meningococcal; method; mg ravulizumab; mice; months; number; open; outcomes; oxygen; participation; patients; period; physical; pneumonia; potential; pregnancy; primary; prior; procedures; progression; protocol; randomization; randomized; ravulizumab; ravulizumab treatment; reactions; records; regulations; regulatory; related; reporting; representative; requirements; respiratory; results; review; risk; sae; saes; safety; samples; sars; score; screening; secondary; section; sensitivity; serum; severe; sf-12; significant; signs; site; soa; sofa; source; spo2; status; studies; study; study day; study drug; study intervention; summary; supportive; survival; symptoms; syndrome; system; table; test; therapies; time; total; treatment; use; vaccination; ventilation; visit; weeks; weight cache: cord-029112-u507i0t0.txt plain text: cord-029112-u507i0t0.txt item: #55 of 134 id: cord-030957-45tc5ksf author: Schaap, Andrew title: The politics of precarity date: 2020-08-28 words: 14973 flesch: 41 summary: Despite being burdened by a 'relentless presentism' that does not allow them to think about, let alone strive for, a better future, it is clear that Apostolidis believes that the 'demand' politics of day workers is suffused with utopian aspirations (p. 68). The question here is whether the 'visionary pragmatism' of day workers is generalizable to other forms of contestation and, if not, in what ways it might be different from the 'principled pragmatism' of the feminist activists outlined above and what might be at stake in these differences. keywords: action; activism; activists; alternative; analysis; anti; apostolidis; approach; bassel; better; black; bodily; book; broad; building; capitalist; category; centers; centres; challenges; change; cis; class; coalitional; collective; colonialism; common; competency; complex; conditions; conscious; context; contrast; convivial; critical; cruel; day; day labourers; death; demand; differences; different; divides; earth; economic; economy; efforts; engels; exception; experiences; fear; feminist; fight; fighting; forms; future; gender; gendered; general; giving; global; groups; hazards; health; help; human; indigenous; intersections; issue; justice; key; kind; knowledge; labor; labourers; large; latino; left; life; lives; lumpenproletariat; maiguashca; marx; means; migrant; mode; movement; multiple; need; new; oppression; organizing; owners; particular; path; paul; people; personal; philanthropy; political; politics; popular; possibilities; possibility; possible; power; practices; pragmatism; precarious; precarity; precarity politics; problem; project; public; question; radical; recognition; refusal; relations; research; resistance; response; responsibility; script; second; self; sense; settler; social; solidarity; spaces; specific; state; struggles; subject; synecdoche; systems; terms; themes; theory; thinking; time; traditional; ultra; understanding; universal; utopian; view; violence; visible; vision; ways; weeks; women; work; workers; working; workplace; world cache: cord-030957-45tc5ksf.txt plain text: cord-030957-45tc5ksf.txt item: #56 of 134 id: cord-031315-p7jb4gf2 author: Kong, Qing title: Efficacy and safety of Jia Wei Bushen Yiqi formulas as an adjunct therapy to systemic glucocorticoids on acute exacerbation of COPD: study protocol for a randomized, double-blinded, multi-center, placebo-controlled clinical trial date: 2020-09-03 words: 8386 flesch: 48 summary: Trial participants, care providers including attending physician and nurse, outcome assessors including PI and sub-PI, and data analysts will be blinded after the assignment of interventions. Plans for communicating important protocol amendments to relevant parties (e.g., trial participants, ethical committees) {25} Any modification to the protocol which may impact the conduct of the study and the potential benefit of the patients will be reported to ethic committee. keywords: acute; acute exacerbation; adjunct; adverse; analysis; assessment; axis; baseline; blinded; blood; case; center; changes; china; chinese; chronic; clinical; clinical trial; committee; copd; copd exacerbation; crf; daily; data; day; day prednisone; days; difference; disease; dose; double; drugs; duration; effects; efficacy; emergency; ethics; events; exacerbation; follow; formulas; function; glucocorticoids; granules; group; herbs; hospital; hospitalization; hpa; huashan; information; informed; investigators; jwby; kidney; laboratory; level; lung; management; medical; medication; medicine; new; number; obstructive; oral; outcomes; participants; patients; physician; placebo; prednisone; primary; protocol; pulmonary; randomized; report; research; respiratory; results; safety; samples; severe; short; site; standard; study; sub; symptoms; syndrome; systemic; table; tcm; term; therapy; time; traditional; treatment; trial; use; variables; visit cache: cord-031315-p7jb4gf2.txt plain text: cord-031315-p7jb4gf2.txt item: #57 of 134 id: cord-032240-xswtx940 author: Sauer, François title: Pericardial effusion in patients with COVID-19: case series date: 2020-09-09 words: 2245 flesch: 47 summary: • A systematic screening for PE should be performed in COVID-19 patients either via a chest computed tomography scan in case of respiratory symptoms, or via transthoracic echocardiography in case of chest pain, haemodynamic instability, or respiratory worsening. Case 3 was a cardiac tamponade due to COVID-19 pericarditis, with a positive polymerase chain reaction on pericardial fluid. keywords: acute; blood; cardiac; case; chest; clinical; colchicine; condition; coronavirus; cov-2; covid-19; day; disease; effusion; emergency; figure; findings; fluid; heart; inflammatory; myocarditis; normal; patient; pcr; pericardial; pericarditis; positive; respiratory; sars; scan; syndrome; tamponade; testing; therapy; treatment; tte cache: cord-032240-xswtx940.txt plain text: cord-032240-xswtx940.txt item: #58 of 134 id: cord-032806-o6p861ms author: Fenin, Audrey title: Very low birth weight infants receive full enteral nutrition within 2 postnatal weeks date: 2020-09-29 words: 3992 flesch: 48 summary: Investigation of how other parameters such as GA, SGA status, and antenatal steroids was not performed in this study but may be of interest in future research of VLBW infant feeding. Despite the lack of difference in 2-year outcomes including survival without moderate or severe neurodevelopmental disability in this trial [9] , neonatal care centers may still find benefit if more rapid advancement of enteral feeds is associated with two common quality indicators in neonatal care-early discontinuation of central venous lines (CVL) and shorter duration of parenteral nutrition (PN), while maintaining infant growth. keywords: addition; advancement; associated; birth; care; change; cohort; cvl; days; difference; early; enteral; epoch; evidence; feeding; feeds; gastric; group; growth; higher; infants; low; lower; nec; neonatal; number; nutrition; outcomes; postnatal; potential; practice; preterm; protocol; sga; study; time; trial; weeks; weight cache: cord-032806-o6p861ms.txt plain text: cord-032806-o6p861ms.txt item: #59 of 134 id: cord-033453-557obi3r author: Bretscher, Lorenzo title: COVID-19 and the Cross-Section of Equity Returns: Impact and Transmission date: 2020-09-24 words: 12248 flesch: 61 summary: In columns 1 and 2, the baseline sample, average nonfinancial firm return is 59.2 bps lower using raw returns and 60.4 bps lower using total returns than the benchmark return calculated from the two days immediately before the event day. In particular, we regress firm level returns on 15 dummies assigned to each day around the event. keywords: analysis; asset; average; bps; case; channel; clustering; coefficients; columns; contractors; coronavirus; counties; county; covid-19; covid-19 dummy; cross; data; day; day levels; day post; days; demand; dependent; double; dummies; dummy; earnings; economic; effect; equity; errors; estimated; event day; event window; evidence; financial; firms; forecast; government; growth; high; home; impact; industry; intensity; intensive; interaction; labor; large; level; level returns; lower; march; market; monetary; negative; pandemic; parentheses; period; policy; post; presents; prices; raw; raw returns; regression; relative; reported; reporting; results; returns; revisions; risk; robust; sample; section; shocks; significant; spread; standard; statistics; staying; stock; subsample; supply; table; total; total returns; uncertainty; variable; window cache: cord-033453-557obi3r.txt plain text: cord-033453-557obi3r.txt item: #60 of 134 id: cord-033791-q0wizf2n author: Kavirayani, Akhila title: The Lazarus effect of very high-dose intravenous anakinra in severe non-familial CNS-HLH date: 2020-10-15 words: 615 flesch: 17 summary: Control GRA NK cells CD107a+ -11.1 % Patient GRA NK cells CD107a+ -Unable to analyse Normal cytotoxic granule release assay as detected by CD107a expression in response to CD3 (T cells) stimulation. Abbreviations: FFP -fresh frozen plasma, PICU -paediatric intensive care unit, PCP -Pneumocystis pneumonia, TPN -total parenteral nutrition Interleukin 1 receptor antagonist to treat cytophagic histiocytic panniculitis with secondary hemophagocytic lymphohistiocytosis Interleukin-1 Receptor Antagonist Penetrates Human Brain at Experimentally Therapeutic Concentrations The effect of intravenous interleukin-1 receptor antagonist on inflammatory mediators in cerebrospinal fluid after subarachnoid haemorrhage: a phase II randomised controlled trial Benefit of Anakinra in Treating Pediatric Secondary Hemophagocytic Lymphohistiocytosis Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patie nts Continuous Intravenous Anakinra Infusion to Calm the Cytokine Storm in Macrophage Activation Syndrome Therapeutic Role of Anakinra, an Interleukin-1 Receptor Antagonist, in the Management of Secondary Hemophagocytic Lymphohistiocytosis/Sepsis/Multiple Organ Dysfunction/Macrophage Activating Syndrome in Critically Ill Children*: Pediatric Anakinra treatment in macrophage activation syndrome: a single center experience and systemic review of literature Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab: Alemtuzumab for Refractory HLH Central nervous system-restricted familial hemophagocytic lymphohistiocytosis responds to hematopoietic cell transplantation Pediatric CNS-isolated hemophagocytic lymphohistiocytosis Neurological associations of COVID-19 keywords: anakinra; antagonist; bal; cells; cns; control; day; dose; gra; hemophagocytic; hlh; hours; interleukin-1; lymphohistiocytosis; macrophage; normal; patient; perforin; receptor; syndrome cache: cord-033791-q0wizf2n.txt plain text: cord-033791-q0wizf2n.txt item: #61 of 134 id: cord-034257-kl2ccmz5 author: de Jonge, Jeroen C. title: PRECIOUS: PREvention of Complications to Improve OUtcome in elderly patients with acute Stroke—statistical analysis plan of a randomised, open, phase III, clinical trial with blinded outcome assessment date: 2020-10-26 words: 3734 flesch: 47 summary: Rationale and design of a randomised, open, phase III, clinical trial with blinded outcome assessment Contemporary outcome measures in acute stroke research Improving the efficiency of stroke trials Statistical analysis of the primary outcome in acute stroke trials Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations None. Medical complications after stroke Characteristic adverse events and their incidence among patients participating in acute ischemic stroke trials Development and internal validation of a prediction rule for post-stroke infection and poststroke pneumonia in acute stroke patients Post-stroke infection: a systematic review and meta-analysis Therapeutic hypothermia in acute ischemic stroke Impact of fever on outcome in patients with stroke and neurologic injury: a comprehensive meta-analysis Effect of hyperthermia on prognosis after acute ischemic stroke Dysphagia after stroke: incidence, diagnosis, and pulmonary complications Temporal profile of body temperature in acute ischemic stroke: relation to infarct size and outcome Poststroke dysphagia: a review and design considerations for future trials Route of feeding as a proxy for dysphagia after stroke and the effect of transdermal glyceryl trinitrate: data from the efficacy of nitric oxide in stroke randomised controlled trial An early rise in body temperature is related to unfavorable outcome after stroke: data from the PAIS study Antibiotic therapy for preventing infections in patients with acute stroke The Paracetamol (Acetaminophen) keywords: acute; allocation; analysis; aspiration; assessment; binary; blinded; ceftriaxone; clinical; complications; daily; data; days; death; effect; fever; final; follow; functional; guidelines; infections; label; logistic; medical; metoclopramide; mrs; onset; open; outcome; paracetamol; patients; population; precious; prevention; primary; protocol; randomised; regression; risk; safety; scale; score; secondary; severe; statistical; stroke; study; table; treatment; trial; use cache: cord-034257-kl2ccmz5.txt plain text: cord-034257-kl2ccmz5.txt item: #62 of 134 id: cord-163587-zjnr7vwm author: Altmejd, Adam title: Nowcasting Covid-19 statistics reported withdelay: a case-study of Sweden date: 2020-06-11 words: 3512 flesch: 58 summary: The moving average of reported deaths is not useful, since it is biased for deaths that occurred within the last week. All three graphs are based on predictions of reported deaths within 14 days, and show how performance increases as more data has been reported. keywords: account; actual; average; benchmark; case; covid-19; daily; data; date; day; days; deaths; delay; distribution; estimates; health; information; intervals; lag; latest; method; model; new; number; parameters; pattern; prediction; probability; public; removal; reporting; reports; statistics; sweden; swedish; trends; true; uncertainty cache: cord-163587-zjnr7vwm.txt plain text: cord-163587-zjnr7vwm.txt item: #63 of 134 id: cord-224211-6lsvjfqb author: Schaback, Robert title: Modelling Recovered Cases and Death Probabilities for the COVID-19 Outbreak date: 2020-03-26 words: 815 flesch: 63 summary: As a byproduct, the above approach provides estimates for the probability to die on day k after confirmation, or to survive after d days. To illustrate the problem, let us assume a form of the 14-day-rule: If a confirmed person survives for d days after confirmation, the person is counted as recovered. keywords: confirmation; covid-19; data; day; days; deaths; outbreak; probabilities; recovered cache: cord-224211-6lsvjfqb.txt plain text: cord-224211-6lsvjfqb.txt item: #64 of 134 id: cord-256015-tt58n0jk author: Zhu, Juanjuan title: Clinical characteristics and therapeutic procedure for a critical case of novel coronavirus pneumonia treated with glucocorticoids and non-invasive ventilator treatment date: 2020-06-01 words: 1351 flesch: 48 summary: Non-invasive ventilator treatment in the early stage of critical disease can reduce the probability of respiratory failure. Subsequently, moxifloxacin and intravenous injection of methylprednisolone (40 mg) were administered, and required assisted respiration with non-invasive ventilator. keywords: admission; clinical; coronavirus; day; glucocorticoids; invasive; lobe; lung; methylprednisolone; min; ncov; ncp; non; normal; novel; oxygen; patient; pneumonia; respiratory; tablets; times; treatment; ventilator cache: cord-256015-tt58n0jk.txt plain text: cord-256015-tt58n0jk.txt item: #65 of 134 id: cord-257654-8u9m1k5q author: Tschöpe, Carsten title: Modulation of the acute defence reaction by eplerenone prevents cardiac disease progression in viral myocarditis date: 2020-07-14 words: 6319 flesch: 32 summary: 5 In summary, our study demonstrates that early treatment with MRA, starting at the acute phase of CVB3 infection, exerted pleiotropic, including immunomodulatory, antioxidative, and anti-apoptotic effects, leading to prevention of adverse cardiac remodelling and dysfunction without affecting viral load, in a murine model of persisting viral myocarditis. Left ventricular (LV) dysfunction in viral myocarditis is attributed to myocardial inflammation and fibrosis, inducing acute and long‐time cardiac damage. keywords: activity; acute; aldosterone; analysis; animals; anova; anti; apoptosis; cardiac; cardiomyocytes; cardiomyopathy; cells; collagen; content; control; coxsackievirus; cvb3; cvb3 infection; damage; data; days; defence; disease; dysfunction; early; effects; end; epl; eplerenone; expression; factor; failure; fibroblasts; fibrosis; figure; gene; group; heart; hl-1; human; immune; infected; infection; inflammation; inflammatory; intervention; left; load; lsd; macrophages; matrix; mean; medium; metalloproteinases; mice; mmp-9; monocytes; myocardial; myocarditis; oxidative; p.i; patients; phase; post; production; reaction; receptor; red; role; saline; sem; significant; staining; stress; study; systolic; test; time; tissue; treatment; type; usa; ventricular; viral; viral myocarditis; way; welch cache: cord-257654-8u9m1k5q.txt plain text: cord-257654-8u9m1k5q.txt item: #66 of 134 id: cord-258696-01wj76es author: Decaro, Nicola title: Experimental infection of dogs with a novel strain of canine coronavirus causing systemic disease and lymphopenia date: 2008-04-30 words: 3449 flesch: 55 summary: The thermal profile consisted of activation of iTaq DNA polymerase at 95 8C for 10 min, followed by 45 cycles of denaturation at 95 8C for 15 s, annealing at 48 8C (type II-specific assay) for 30 s and extension at 60 8C for 1 min. Plasma samples from inoculated dogs were tested in parallel by virus neutralisation (VN) and ELISA tests (Pratelli et al., 2002) . key: cord-258696-01wj76es authors: Decaro, Nicola; Campolo, Marco; Lorusso, Alessio; Desario, Costantina; Mari, Viviana; Colaianni, Maria Loredana; Elia, Gabriella; Martella, Vito; Buonavoglia, Canio title: Experimental infection of dogs with a novel strain of canine coronavirus causing systemic disease and lymphopenia date: 2008-04-30 journal: Vet Microbiol DOI: 10.1016/j.vetmic.2007.10.008 sha: doc_id: 258696 cord_uid: 01wj76es A pantropic canine coronavirus (CCoV) strain (CB/05) has been recently associated to a fatal outbreak of systemic disease in young dogs. keywords: animals; blood; canine; cb/05; ccov; cell; clinical; coronavirus; counts; days; decaro; disease; dogs; euthanized; fig; infected; infection; inoculated; month; old; organs; p.i; pcr; peak; pups; real; rna; samples; severe; signs; strain; template; time; titres; total; type; viral; virus; wbc cache: cord-258696-01wj76es.txt plain text: cord-258696-01wj76es.txt item: #67 of 134 id: cord-265891-jmpterrj author: Eilersen, Andreas title: Cost–benefit of limited isolation and testing in COVID-19 mitigation date: 2020-10-29 words: 3930 flesch: 52 summary: We find that workplace and more diffuse social contacts are roughly equally important to disease spread, and that an effective lockdown must target both. In the figure, we see that the effects of reducing workplace and social contacts are roughly of the same magnitude. keywords: agent; available; average; contacts; cost; covid-19; days; disease; distribution; duration; effect; efficiency; epidemic; families; family; fig; figure; friends; groups; incubation; infected; infection; lockdown; mitigation; model; number; pandemic; peak; people; period; person; possible; probability; public; quarantine; reduction; size; social; society; spread; stage; step; strategy; testing; time; transmission; workplace cache: cord-265891-jmpterrj.txt plain text: cord-265891-jmpterrj.txt item: #68 of 134 id: cord-266156-xmf4emln author: Miller, Tyler E. title: Clinical sensitivity and interpretation of PCR and serological COVID‐19 diagnostics for patients presenting to the hospital date: 2020-08-28 words: 4336 flesch: 38 summary: We modeled a linear daily regression trend after first positive PCR test, to estimate the time when PCR sensitivity reaches zero (foot-point analysis). Second, we also modeled how PCR sensitivity decreases over time after the first positive PCR test (Figures S3 and S5 ). keywords: acute; aid; analysis; antibodies; antibody; assay; available; clinical; cohort; coronavirus; course; cov-2; covid-19; data; date; days; detection; diagnostic; disease; elisa; figure; grants; hospital; iga; igg; igm; infection; interpretation; isotype; laboratory; modalities; multiple; onset; patients; pcr; performance; positive; post; prior; rbd; reports; respiratory; response; results; sars; sensitivity; seroconversion; serologic; serology; severe; specific; study; subset; symptom; symptom onset; symptomatic; syndrome; table; technical; test; testing; time cache: cord-266156-xmf4emln.txt plain text: cord-266156-xmf4emln.txt item: #69 of 134 id: cord-266183-uzuda3ir author: Renieris, Georgios title: Serum Hydrogen Sulfide and Outcome Association in Pneumonia by the SARS-CoV-2 Corona virus date: 2020-05-18 words: 2212 flesch: 43 summary: A novel coronavirus from patients with pneumonia in China Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The perspectives of clinical immunologists from China CII: Pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors Hydrogen sulfide signaling in mitochondria and disease Sulfur compounds block MCP-1 production by Mycoplasma fermentans-infected macrophages through NF-κB inhibition Hydrogen sulfide attenuates atherosclerosis in a partially ligated carotid artery mouse model via regulating angiotensin converting enzyme 2 expression Survival predictors in elderly patients with acute respiratory distress syndrome: a prospective observational cohort study Pneumonia severity index in viral community acquired pneumonia in adults Unauthorized reproduction of this article is prohibited Analysis of endogenous H2S and H2Sn in mouse brain by high-performance liquid chromatography with fluorescence and tandem mass spectrometric detection Measurement of plasma hydrogen sulfide in vivo and in vitro Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirusinfected pneumonia in Wuhan The role of H2S bioavailability in endothelial dysfunction The assessment of endothelial function: from research into clinical practice Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan The cytokine release syndrome (CRS) of severe COVID-19 and Interleukin-6 receptor (IL-6R) antagonist tocilizumab may be the key to reduce the mortality Inhaled Hydrogen sulfide prevents endotoxin-induced systemic inflammation and improves survival by altering sulfide metabolism in mice We furtherinvestigated the association between over-time change of serum H2S and outcome. keywords: absolute; admission; analysis; article; association; blood; clinical; count; cov-2; covid-19; crp; data; day; days; death; endothelial; equal; factor; figure; greater; h2s; higher; hydrogen; il-6; inflammatory; levels; mortality; outcome; patients; pneumonia; reproduction; sars; serum; severity; shock; study; sulfide; survival; survivors; unauthorized cache: cord-266183-uzuda3ir.txt plain text: cord-266183-uzuda3ir.txt item: #70 of 134 id: cord-266571-qbskh1uu author: de Arriba, M.L title: Lymphoproliferative responses and protection in conventional piglets inoculated orally with virulent or attenuated porcine epidemic diarrhoea virus date: 2002-06-04 words: 5107 flesch: 34 summary: After the challenge, there was an increase in the lymphocyte proliferative response in pigs from group 1, however this increase was not reflected either by an enhancement of the virus-specific antibody secreting cell response or the GMT of PEDV-specific serum IgG and IgA (De Arriba et al., 2001b) . Lymphocyte proliferation responses of transmissible gastroenteritis virus or porcine respiratory coronavirus Cellular immune responses of pigs after primary inoculation with porcine respiratory coronavirus or transmissible gastroenteritis virus and challenge with transmissible gastroenteritis virus Evaluation of a bloking ELISA using monoclonal antibodies for the detection of porcine epidemic diarrhea virus and its antibodies Seroprevalence of porcine epidemic diarrhea virus infection among different types of breeding swine farms in Spain Revision of the taxonomy of the Coronavirus, Torovirus and Arterivirus genera Antibody-mediated protection of mucosal surfaces Isotype-specific antibody-secreting cells in systemic and mucosal associated lymphoid tissues and antibody responses in serum of conventional pigs inoculated with PEDV Mucosal and systemic isotype-specific antibody responses and protection in conventional pigs exposed to virulent or attenuated porcine epidemic diarrhoea virus Quantitation, biological and physicochemical properties of cell culture-adapted porcine epidemic diarrhea coronavirus (PEDV) keywords: animals; antibody; antigen; attenuated; blood; cells; challenge; control; cpm; day; days; diarrhoea; differences; disease; epidemic; et al; gastroenteritis; group; higher; immune; immunity; infection; inoculated; lymph; lymphocyte; lymphoid; lymphoproliferative; mean; mesenteric; mononuclear; mucosal; nodes; pedv; pigs; porcine; postchallenge; postinoculation; postinoculation day; proliferation; protection; responses; specific; spleen; systemic; tissues; transmissible; unexposed; value; viral; virulent; virus cache: cord-266571-qbskh1uu.txt plain text: cord-266571-qbskh1uu.txt item: #71 of 134 id: cord-268081-ytx6sf3x author: Guionie, Olivier title: An experimental study of the survival of turkey coronavirus at room temperature and +4°C date: 2013-04-22 words: 4057 flesch: 49 summary: Furthermore, the survival of Fr TCoV is only one possible factor that might contribute to the seasonality of the disease, and other possibly more significant interfering factors, such as possible vectors or seasonality of turkey production, might also play a role, so that Fr TCoV virus survival according to the outdoor temperature might not be the most important parameter for its transmission between turkey flocks. The period of highest PEC incidence hence appears not to be the most favourable for Fr TCoV survival in the environment. keywords: /ml; 48c; coronavirus; data; days; decrease; detection; different; eggs; eid; embryos; enteritis; environment; et al; flocks; france; ibv; infectious; inoculated; inoculation; log; maurel; mhv; pcr; pec; positive; presence; real; residual; rna; room; samples; specific; spf; stability; storage; study; survival; suspension; tcov; temperature; time; titre; turkey; virus; viruses cache: cord-268081-ytx6sf3x.txt plain text: cord-268081-ytx6sf3x.txt item: #72 of 134 id: cord-268341-103xf3dw author: Parra, Beatriz title: Kinetics of Cytokine mRNA Expression in the Central Nervous System Following Lethal and Nonlethal Coronavirus-Induced Acute Encephalomyelitis date: 1997-07-07 words: 5792 flesch: 41 summary: TNF-a mRNA is induced following JHMV infection level of IL-12 mRNA in 2.2v-1-infected mice suggests the possibility that oligodendroglia transcribe IL-12 mRNA in (Pearce et al., 1994; Stohlman et al., 1995a; Sun et al., 1995) and TNF-a is present during both the acute and response to JHMV infection, similar to the induction of IL-12 mRNA following measles virus infection of oligo-persistent JHMV infections. infected mice, suggesting a rapid response to virus infection. keywords: accumulation; acute; analysis; antibodies; antigen; associated; astrocytes; cd4; cells; central; clearance; cns; consistent; contrast; coronavirus; cua; cytokine; data; day; days; demyelination; early; effectors; encephalitis; encephalomyelitis; et al; expression; fig; fleming; groups; hepatitis; ifn; il-12; il-4; il-6; immune; immunodeficient; increased; induced; induction; infected; infection; inos; jhmv; kinetics; lethal; lethally; levels; mechanisms; mice; mouse; mrna; nervous; p.i; peak; pearce; persistent; protection; rapid; replication; response; role; sham; specific; stohlman; subacute; sublethal; system; th1; th2; tnf; variant; viral; virus; viruses; vitro; vivo; williamson cache: cord-268341-103xf3dw.txt plain text: cord-268341-103xf3dw.txt item: #73 of 134 id: cord-271180-cnrs0zpg author: Rizvi, Saniya title: Cytosorb Filter: An adjunct for survival in the COVID-19 patient in cytokine storm? A case report. date: 2020-09-18 words: 3900 flesch: 47 summary: 2 It has been successfully used in cytokine storm patients previously with septic shock, severe pro-inflammatory state in post-operative conditions. Chest x-ray on hospital day 11 which coincided with the first day of cytokine filter therapy showing persistence of infiltrates, improved aeration and improved right lower lobe consolidation. keywords: acute; alveolar; ards; bilateral; blood; case; chest; covid-19; crrt; cytokine; cytosorbents; daily; day; days; distress; dysfunction; fever; figure; filter; hemodynamic; hospital; hours; hypoxia; il-6; ill; illness; improved; infiltrates; inflammatory; initial; initiation; laboratory; lung; oxygen; patient; peep; positive; pressor; prior; protocol; pulmonary; ray; renal; replacement; report; requirements; respiratory; results; right; severe; shock; state; storm; support; table; team; therapy; treatment; use; ventilator; volume cache: cord-271180-cnrs0zpg.txt plain text: cord-271180-cnrs0zpg.txt item: #74 of 134 id: cord-271298-7vk3wgw1 author: Sato, Tomoi title: Feeding behavior during sialodacryoadenitis viral infection in rats date: 2001-04-30 words: 3281 flesch: 44 summary: Thus, the similarity in pattern of decreased food intake during the SDA viral infection and that during indomethacin-induced ulcerative ileitis, suggests a mechanistic link between viral infection, TNF-a, and anorexia. After infection food intake decreased by 68%. keywords: acute; anorexia; average; bacterial; body; changes; colony; dark; data; day; days; decrease; dopamine; feeding; food; food intake; increase; induced; infection; influenza; intake; kcal; light; meal; meal number; meal size; mice; number; pattern; phase; rats; response; role; sda; significant; size; tnf; viral; viral infection; virus; weight cache: cord-271298-7vk3wgw1.txt plain text: cord-271298-7vk3wgw1.txt item: #75 of 134 id: cord-274497-tqceazdp author: N. Nuñez, Luis Fabian title: Molecular Characterization and Pathogenicity of Chicken Parvovirus (ChPV) in Specific Pathogen-Free Chicks Infected Experimentally date: 2020-07-25 words: 4125 flesch: 42 summary: Molecular characterization and typing of chicken and turkey astroviruses circulating in the United States: Implications for diagnostics Partial genome sequence analysis of parvoviruses associated with enteric disease in poultry Molecular characterization of avian astroviruses Host Specificity and Phylogenetic Relationships of Chicken and Turkey Parvoviruses Enteric Virus Diversity Examined by Molecular Methods in Brazilian Poultry Flocks Development of a sensitive real-time Fast-qPCR Based on SYBR ® green for detection and quantification of Chicken Parvovirus (ChPV) Detection of rotaviruses and intestinal lesions in broiler chicks from flocks with runting and stunting syndrome (RSS) Detection of chicken astrovirus by reverse transcriptase-polymerase chain reaction Development and evaluation of real-time TaqMan ® RT-PCR assays for the detection of avian nephritis virus and chicken astrovirus in chickens Emergence of Enteric Viruses in Production Chickens is a Concern for Avian Health Capsid protein sequence diversity of avian nephritis virus Chicken astrovirus as an aetiological agent of runting-stunting syndrome in broiler chickens Presence of parvoviruses in the intestine of chickens showing stunting syndrome Experimental infection of chicken embryos and day-old chickens with parvovirus of chicken origin High prevalence of turkey parvovirus in turkey flocks from Hungary experiencing enteric disease syndromes Samorek-Salamonowicz, E. Occurrence of chicken parvovirus infection in poland Parvovirus host range, cell tropism and evolution Recent Progress in the Characterization of Avian Enteric Viruses Determination and analysis of the full-length chicken parvovirus genome Identification and phylogenetic diversity of parvovirus circulating in commercial chicken and turkey flocks in Croatia Molecular detection of chicken parvovirus in broilers with enteric disorders presenting curving of duodenal loop, pancreatic atrophy, and mesenteritis Chicken parvovirus-induced runting-stunting syndrome in young broilers Genetic characterization of three novel chicken parvovirus strains based on analysis of their coding sequences Development of an Enzyme-Linked Immunosorbent Assay to Detect Chicken Parvovirus-Specific Antibodies Development of a Polymerase Chain Reaction Procedure for Detection of Chicken and Turkey Parvoviruses A novel tool for specific detection and quantification of chicken/turkey parvoviruses to trace poultry fecal contamination in the environment Chicken parvovirus viral loads in cloacal swabs from malabsorption syndrome-affected and healthy broilers Avian parvovirus: Classification, phylogeny, pathogenesis and diagnosis Genetic characterization of parvoviruses circulating in turkey and chicken flocks in Poland Naturally occurring parvoviral infection in Hungarian broiler flocks Investigation into the aetiology of runting and stunting syndrome in chickens Periodic Monitoring of Commercial Turkeys for Enteric Viruses Indicates Continuous Presence of Astrovirus and Rotavirus on the Farms Phylogenetic diversity of avian nephritis virus in Hungarian chicken flocks Detection of enteric viruses in pancreas and spleen of broilers with runting-stunting syndrome (RSS) Isolation and molecular characterisation of chicken parvovirus from Brazilian flocks with enteric disorders MEGA7: The lack of ChPV VP1 gene sequences could likely be related to the difficulty in ChPV DNA isolation for whole VP1 gene sequencing; however, the majority of published works have included a molecular characterization of the NS gene sequence [15, 16] . keywords: age; animals; birds; brazil; cells; characterization; chicken; chicks; chpv; clinical; complete; crypt; day; days; detection; diarrhea; dna; duodenal; duodenum; enteric; experimental; figure; flocks; gene; genome; group; ileum; infected; infection; intestinal; isolated; jejunum; loop; mock; molecular; number; organs; pancreas; parvovirus; post; presence; present; qpcr; rss; sequences; similarity; strain; stunting; syndrome; table; turkey; viral; viruses; vp1 cache: cord-274497-tqceazdp.txt plain text: cord-274497-tqceazdp.txt item: #76 of 134 id: cord-274860-7ec2jcoq author: Salazar, Eric title: Significantly decreased mortality in a large cohort of COVID-19 patients transfused early with convalescent plasma containing high titer anti-SARS-CoV-2 spike protein IgG date: 2020-11-04 words: 4748 flesch: 40 summary: Retrospective analysis by the Ortho VITROS IgG assay revealed a median signal/cutoff (S/C) ratio of 24.0 for transfused units, a value far exceeding the recently FDA-required cutoff of 12.0 for designation of high titer convalescent plasma. With respect to altering mortality, our analysis identified an optimal window of 44 hours post-hospitalization for transfusing COVID-19 patients with high titer convalescent plasma. keywords: admission; analysis; anti; antibody; available; baseline; clinical; cohort; controls; convalescent; convalescent plasma; cov-2; covid-19; data; day; days; death; disease; early; findings; high; highest; hospitalization; hrs; igg; matching; median; mortality; multivariate; ortho; outcome; patients; plasma; point; post; propensity; protein; randomized; rbd; rbd igg; relative; results; sars; score; significant; spike; studies; study; supplemental; titer; transfusion; trial; units; use; ventilation; vitros cache: cord-274860-7ec2jcoq.txt plain text: cord-274860-7ec2jcoq.txt item: #77 of 134 id: cord-275427-00bwhaga author: Aydogdu, Ugur title: The determination of treatment effect of chitosan oligosaccharide in lambs with experimentally cryptosporidiosis date: 2019-11-30 words: 5219 flesch: 50 summary: While all the lambs in the positive control group had oocyst excretion at the level of +1 on the 14th and 21st days, this level was found to be lower in treatment groups compared to the positive control group. key: cord-275427-00bwhaga authors: Aydogdu, Ugur; Coskun, Alparslan; Atas, Ahmet Duran; Basbug, Onur; Agaoglu, Zahid Tevfik title: The determination of treatment effect of chitosan oligosaccharide in lambs with experimentally cryptosporidiosis date: 2019-11-30 journal: Small Ruminant Research DOI: 10.1016/j.smallrumres.2019.09.021 sha: doc_id: 275427 cord_uid: 00bwhaga Abstract keywords: 14th; 1st; 21st; 2nd; 3rd; 5th; 7th; analysis; blood; body; calves; cases; cell; changes; chitosan; clinical; control; cos; cryptosporidiosis; cryptosporidium; day; days; dehydration; diarrhea; difference; doses; drug; effects; efficacy; et al; excretion; experimental; findings; group; increases; infected; infection; lactate; lambs; levels; oligosaccharide; oocyst; oral; parvum; positive; samples; significant; stool; studies; study; temperature; terms; treatment; weight cache: cord-275427-00bwhaga.txt plain text: cord-275427-00bwhaga.txt item: #78 of 134 id: cord-275828-c6d6nk7x author: Mikasa, Keiichi title: JAID/JSC Guidelines for the Treatment of Respiratory Infectious Diseases: The Japanese Association for Infectious Diseases/Japanese Society of Chemotherapy – The JAID/JSC Guide to Clinical Management of Infectious Disease/Guideline-preparing Committee Respiratory Infectious Disease WG date: 2016-07-31 words: 39699 flesch: 37 summary: In the treatment of hospital-acquired pneumonia, the duration of antimicrobial therapy generally tends to be longer than required for the following reasons: opacity on chest X-ray often remains for reasons other than pneumonia even after the start of antimicrobial drug treatment; and there may be a large number of latent nonpneumonia (or non-infectious-disease) factors that may cause increase in body temperature or CRP level in inpatients (Table 5 GNR b ), the expression of intrinsic antimicrobial-drugresistance genes encoded in chromosome genes is induced during antimicrobial drug treatment, a phenomenon which is basically rarely seen in E. coli, Klebsiella spp., H. influenzae, and M. catarrhalis (Table 5 GNR a ) ( Table 5) keywords: ---executive; -azm; -cam; -ctrx; -lvfx; -the; abpc; absence; accordance; acinetobacter; activities; activity; acute; addition; administration; admission; adults; aeruginosa; aged; aii; airway; ampc; anaerobes; analysis; antibiotic; antigen; antimicrobial; antimicrobial drugs; antimicrobial therapy; antimicrobial treatment; appropriate; aspergillosis; aspiration pneumonia; atypical; atypical pneumonia; aureus; bacteria; bacterial pneumonia; basic; bii; biii; blood; bronchiolitis; bronchitis; care; cases; catarrhalis; causative; causative microorganisms; cause; cavity; cephems; characteristics; chemotherapy; chest; childhood; children; choices; chronic; classification; cldm; clinical; coli; combination; combination therapy; committee; community; comparison; condition; control; cough; course; culture; data; day; day -ctx; day -drpm; day -lvfx; day -mepm; day -mino; day -pzfx; day þ; days; definitive; diagnosis; difference; difficult; diffuse; disease; disorder; dose; double; drug; drug susceptibility; drug therapy; drug treatment; dysfunction; early; effective; effects; efficacy; effusion; elderly; empiric; enteric; eosinophilia; esbl; evidence; examination; factors; fever; findings; fluid; following; frequency; frequent; g/2e3; g/3e4; g/3e4 times; general; generation; gram; group; guidelines; hand; health; high; hospital; hospital treatment; human; immunodeficiency; important; improvement; incidence; increase; infected; infection; infectious diseases; influenza; inh; initial; intensive; intravenous drip; intravenous injection; invasive; involvement; isolated; japan; japanese; kg/3; kg/3 times; klebsiella; laboratory; lactamase; larvae; legionella; lesions; level; liver; long; lower; lung; macrolide; management; marked; maximum; medical; method; microorganisms; monotherapy; months; mortality; mrsa; mrsa pneumonia; multi; mycobacterium; mycoplasma; necessary; negative; neonatal; new; nhcap; non; nosocomial; number; nursing; observed; onset; options; oral; oral administration; oral drugs; outpatient; particular; pathogens; patients; pediatric; penicillin; period; peripheral; phase; pipc; pleural; pneumonia; positive; possible; potent; practice; preparation; presence; prevention; pulmonary; purulent; pyothorax; quinolones; randomized; rate; ray; regimens; resistant; resistant bacteria; respect; respiratory; respiratory infectious; response; results; review; rfp; risk; sbt; second; secondary; section; selection; severe; severe pneumonia; severity; shadow; similar; single; society; spectrum; spp; sputum; staining; standard; status; strains; streptococcus; studies; study; susceptibility; symptoms; syndrome; table; term; test; therapy; thoracic; times; tract; treatment; treatment period; trial; tuberculosis; type; underlying; useful; vap; ventilator; viral; virus; viruses; weeks; years; younger cache: cord-275828-c6d6nk7x.txt plain text: cord-275828-c6d6nk7x.txt item: #79 of 134 id: cord-275889-4qwp3um1 author: Guarnieri, M. title: Subcutaneous Implants of a Cholesterol-Triglyceride-Buprenorphine Suspension in Rats date: 2017-04-09 words: 6875 flesch: 52 summary: Overall, there were no significant changes in body weights between the vehicle control and drug treated rats. Female rats were used because mu opioid agonists such as morphine appear to be less sensitive in female than male rats keywords: analgesia; anesthesia; animals; bedding; behavior; blood; buprenorphine; changes; cholesterol; clean; clinical; collection; concentrations; control; data; day; days; delivery; differences; dose; dose group; dose trial; drug; effects; efficacy; excess; female; female rats; greater; group; hair; highest; histopathology; induced; injection; kg dose; laboratory; levels; lipid; long; loss; males; max; mean; mice; model; morphine; nausea; normal; number; observation; observed; organ; pain; pica; plasma; present; protein; rate; rats; release; repeat; safety; samples; self; sex; significant; signs; single; skin; standard; studies; study; subcutaneous; surgery; suspension; sustained; system; table; tas; term; tests; therapy; time; tissues; trial; urine; values; vehicle; weight cache: cord-275889-4qwp3um1.txt plain text: cord-275889-4qwp3um1.txt item: #80 of 134 id: cord-276338-wpo1eyeg author: Hesse, Amke title: In toxic demyelination oligodendroglial cell death occurs early and is FAS independent date: 2009-10-22 words: 5505 flesch: 42 summary: key: cord-276338-wpo1eyeg authors: Hesse, Amke; Wagner, Michael; Held, Jasmin; Brück, Wolfgang; Salinas-Riester, Gabriela; Hao, Zhenyue; Waisman, Ari; Kuhlmann, Tanja title: In toxic demyelination oligodendroglial cell death occurs early and is FAS independent date: 2009-10-22 journal: Here, we demonstrate that in the toxic demyelination cuprizone model, oligodendroglial cell death and downregulation of myelin genes start days after initiation of the cuprizone diet and weeks before demyelination is obvious. keywords: agilent; anti; apoptosis; apoptotic; brain; callosum; caspase; cell; cell death; cnpase; condensed; controls; corpus; cuprizone; cuprizone diet; cuprizone model; data; days; death; demyelination; diet; early; et al; expression; fas; fed; fig; fragmented; gene; germany; human; immunohistochemistry; later; lfb; macrophages; mbp; mechanisms; mice; model; multiple; nogo; nuclei; number; observed; oligodendrocytes; oligodendroglial; oligodendroglial cell; p53; positive; rna; sclerosis; significantly; spinal; stages; staining; start; time; weeks cache: cord-276338-wpo1eyeg.txt plain text: cord-276338-wpo1eyeg.txt item: #81 of 134 id: cord-277077-kwaiorp8 author: Tița, Ovidiu title: Use of Yoghurt Enhanced with Volatile Plant Oils Encapsulated in Sodium Alginate to Increase the Human Body’s Immunity in the Present Fight Against Stress date: 2020-10-19 words: 8120 flesch: 55 summary: According to various recent studies, volatile oils from various aromatic plants have a high content of antioxidants and antimicrobial compounds. The main purpose of this paper is to create a yoghurt with high antioxidant capacity, using only raw materials from Romania; (2) Methods: The bioactive components used to enrich the cow milk yoghurt were extracted as volatile oils out of four aromatic plants: basil, mint, lavender and fennel. keywords: 10th day; 20th; addition; alginates; analysis; antimicrobial; antimicrobial activity; antioxidant activity; antioxidant capacity; antioxidants; area; aromatic; average; average value; basil oil; body; case; chemical; compounds; control sample; covid-19; cow; cow milk; culture; day; days; decline; dpph; effects; essential; essential oil; extraction; fennel; fennel oil; figure; food; free; health; higher; highest; highest antioxidant; highest value; human; increase; lavender; lavender oil; lower; lowest; lowest antioxidant; lowest value; method; milk; milk yoghurt; mint oil; mixture; oil; oils; plants; products; properties; radicals; results; romania; samples; smaller; sodium; sodium alginate; stress; studies; use; value; volatile; volatile basil; volatile fennel; volatile lavender; volatile mint; volatile oil; yoghurt sample cache: cord-277077-kwaiorp8.txt plain text: cord-277077-kwaiorp8.txt item: #82 of 134 id: cord-278224-sq7tokbx author: Protopopova, Alexandra title: Behavioral predictors of subsequent respiratory illness signs in dogs admitted to an animal shelter date: 2019-10-23 words: 7591 flesch: 45 summary: The high levels of cortisol (or corticosterone) inhibit further production of the CRH and ACTH resulting in a negative feedback loop (see [14] for a discussion in shelter dogs). Management of Disease Outbreaks in Animal Shelters Bold personality makes domestic dogs entering a shelter less vulnerable to diseases A placebo-controlled trial of two intranasal vaccines to prevent tracheobronchitis (kennel cough) in dogs entering a humane shelter The effects of exercise and calm interactions on in-kennel behavior of shelter dogs In-kennel behavior predicts length of stay in shelter dogs Development and validation of a body condition score system for dogs Behavior and cortisol levels of dogs in a public animal shelter, and an exploration of the ability of these measures to predict problem behavior after adoption Tools for Partial Least Squares Path Modeling (PLS-PM) keywords: activity; agreement; analysis; animal; animal shelter; anxiety; assessment; behavior; boldness; canine; car; care; cirdc; collection; complex; correlated; correlation; cortisol; coughing; curiosity; data; day; days; discharge; disease; dogs; effects; environment; function; future; health; higher; human; hypothesis; illness; immune; immunodeficiency; individual; infectious; intake; interval; kennel; latent; life; likely; low; lower; management; min; model; nasal; number; observation; observer; occurrence; path; pathogens; personality; present; previous; ratio; relationship; research; respiratory; risk; scores; second; shelter; significant; signs; sociability; social; species; standardized; stress; study; subsequent; system; table; temperament; temperature; test; time; traits; urine; vaccination; variables; videos; virus cache: cord-278224-sq7tokbx.txt plain text: cord-278224-sq7tokbx.txt item: #83 of 134 id: cord-280242-2w2kl0uf author: Kaya, Yildiz title: Transient cortical blindness in COVID-19 pneumonia; a PRES-like syndrome: A case report date: 2020-04-28 words: 767 flesch: 39 summary: In this disease, main pathological change is brain edema without evidence of inflammation on cerebrospinal fluid analysis. Recent autopsy reports have revealed that, like many viral infections SARS-CoV-2 can cause brain tissue edema and partial neuronal degeneration [3] . keywords: acute; blood; brain; cov-2; covid-19; day; edema; encephalopathy; examination; infection; neurological; normal; oxygen; patient; pneumonia; pres; reversible; sars; syndrome; systemic cache: cord-280242-2w2kl0uf.txt plain text: cord-280242-2w2kl0uf.txt item: #84 of 134 id: cord-280821-kc0ut4oy author: Venturini, Elisabetta title: Treatment of children with COVID-19: position paper of the Italian Society of Pediatric Infectious Disease date: 2020-09-24 words: 5485 flesch: 38 summary: At present, few clinical trials for COVID-19 treatment involving children are ongoing [8] . Currently, American guidelines on COVID-19 treatment published in May 2020, recommend both in children and adults to use lopinavir/ritonavir only in the context of clinical trials, given the lack of effectiveness reported now in literature [9, 12] . keywords: activity; acute; adults; age; anakinra; antiviral; assessment; associated; available; azithromycin; care; case; children; chinese; clinical; combination; committee; coronavirus; cov-2; covid-19; cytokine; data; days; dimer; disease; dosage; drug; early; efficacy; evidence; fda; fever; guidelines; health; high; hydroxychloroquine; il-6; infection; inflammatory; infusion; italian; life; literature; lopinavir; lower; management; mild; mortality; national; new; non; novel; observational; ongoing; patients; pediatric; pneumonia; possible; remdesivir; respiratory; results; risk; ritonavir; sars; scientific; sepsis; severe; society; start; storm; studies; study; suggested; symptoms; syndrome; therapeutic; therapy; tocilizumab; treatment; trial; use cache: cord-280821-kc0ut4oy.txt plain text: cord-280821-kc0ut4oy.txt item: #85 of 134 id: cord-282158-08u3x1z4 author: Yang, William H. title: Long-term immunogenicity of an AS03-adjuvanted influenza A(H1N1)pdm09 vaccine in young and elderly adults: An observer-blind, randomized trial() date: 2013-09-13 words: 5330 flesch: 42 summary: The World Health Organization (WHO) encouraged the development and use of adjuvanted influenza A(H1N1)pdm09 vaccines [9, 10] , with the aim of dose-reduction, antigen-sparing and to potentially provide broader vaccine efficacy against drifted strains through cross-reactive immunity [11] . Based on the experience of developing a pre-pandemic A/H5N1 influenza vaccine utilizing AS03 (an ␣-tocopherol oil-in-water emulsion based Adjuvant System) keywords: a(h1n1)pdm09; adjuvanted; adults; adverse; age; age group; antibody; antigen; as03; cases; cber; clinical; criteria; data; day; days; dose; efficacy; events; glaxosmithkline; group; higher; ili; immune; immunogenicity; influenza; influenza a(h1n1)pdm09; influenza vaccine; month; non; pandemic; previous; primary; protective; randomized; regulatory; related; respiratory; response; safety; samples; scr; seasonal; solicited; spr; strain; study; subjects; system; table; time; treatment; trial; vaccination; vaccine; virus; years; years age cache: cord-282158-08u3x1z4.txt plain text: cord-282158-08u3x1z4.txt item: #86 of 134 id: cord-282268-f7mbdfr6 author: Cartenì, Armando title: How mobility habits influenced the spread of the COVID-19 pandemic: Results from the Italian case study date: 2020-06-24 words: 5280 flesch: 32 summary: Within this topic, the aim of the paper was to quantify the effect of mobility habits in the spread of the Coronavirus in Italy through a multiple linear regression model. Estimation results showed that mobility habits represent one of the variables that explains the number of COVID-19 infections jointly with the number of tests/day and some environmental variables (i.e. PM pollution and temperature). keywords: area; average; cases; certified; china; codogno; contagion; coronavirus; countries; covid-19; daily; day; days; decay; detection; e.g.; economic; estimation; example; habits; health; higher; incubation; italian; italy; lockdown; mobility; mobility habits; model; national; new; number; old; outbreak; pandemic; paper; people; period; pollution; population; region; regional; research; respect; restrictions; results; significant; source; spread; temperature; time; transport; trips; variable; year cache: cord-282268-f7mbdfr6.txt plain text: cord-282268-f7mbdfr6.txt item: #87 of 134 id: cord-283257-rh3bxvv7 author: Andrejčáková, Zuzana title: Synbiotics suppress the release of lactate dehydrogenase, promote non‐specific immunity and integrity of jejunum mucosa in piglets date: 2015-12-21 words: 4574 flesch: 32 summary: New studies (Imani Fooladi et al. 2013) have confirmed that probiotics have significant effect on the health status of the liver and the ability to treat various liver diseases. Daugschies et al. (2000) noticed subsequent decrease in the activity of TLDH in muscles of calves after experimental infection with Sarcocystis cruzi, which may also be affected by enhancing the release of LDH into the bloodstream during ongoing infection. keywords: -biocenol; ability; acids; activity; animals; blood; ccm; cell; cheese; coli; concentration; control; data; day; days; decrease; dehydrogenase; diarrhea; diet; effect; enterotoxigenic; et al; experimental; extracts; fatty; feces; feeding; flaxseed; group; growth; health; immune; immunity; increase; index; infection; inflammatory; integrity; intestinal; isoenzymes; jejunum; lactate; lactobacillus; ldh; levels; liver; means; membrane; metabolic; mucosa; n-3; n-6; performance; period; piglets; pigs; plantarum; polyunsaturated; presence; probiotic; production; pufas; release; republic; samples; serum; significant; slovak; specific; strain; study; synbiotics; table; tissue; tldh; values; villi; weaning; weanlings cache: cord-283257-rh3bxvv7.txt plain text: cord-283257-rh3bxvv7.txt item: #88 of 134 id: cord-285096-g9y3au1a author: Mitchell, Judy A. title: Tropism and pathological findings associated with canine respiratory coronavirus (CRCoV) date: 2013-03-23 words: 7136 flesch: 44 summary: When studied in isolation dogs infected with other viruses involved in the CIRD complex, such as CPIV and CAV-2, also cause only mild respiratory disease such as a dry cough and nasal discharge (Appel and Binn, 1987a,b; Castleman, 1985; Buonavoglia and Martella, 2007) . Following experimental infection in dogs, all five CRCoV isolates gave rise to clinical signs of respiratory disease consistent with that observed during natural infection. keywords: analysis; blood; bronchial; canine; cells; challenge; changes; cilia; cird; clinical; concentrations; consistent; control; coronavirus; crcov; culture; data; day; days; differences; disease; dogs; erles; et al; experimental; findings; fluid; groups; histological; infected; infection; inflammation; isolates; isolation; lavage; lobe; lung; lymphoid; marked; mild; nares; nasal; negative; neutrophil; observed; overall; pathogenesis; pcr; positive; presence; priestnall; rectal; respiratory; respiratory disease; role; samples; score; serum; severe; shedding; significant; signs; strains; study; swabs; table; tissues; tonsil; trachea; tract; treatment; tropism; usa; viral cache: cord-285096-g9y3au1a.txt plain text: cord-285096-g9y3au1a.txt item: #89 of 134 id: cord-285812-l7dpv6nx author: O’TOOLE, D. title: Pathogenicity of experimental infection with ‘pneumotropic’ porcine coronavirus date: 1989-07-31 words: 3074 flesch: 42 summary: The uninoculated, control piglets remained seronegative throughout the study period. Owing to its similarity to TGEV, the changes In r-ev-infected piglets were compared with those in piglets foIlowing TGEV infection. keywords: alveolar; antigen; atrophy; bronchiolar; bronchointerstitial; cells; cent; control; coronavirus; cultures; days; enterocytes; epithelium; fig; gastroenteritis; infection; inoculation; isolate; isolation; isolators; kidney; lesions; lung; macrophages; mild; multifocal; necrosis; pap; pcv; piglets; pneumonia; porcine; positive; present; respiratory; rev; signs; similar; small; study; terminal; test; tgev; tissues; transmissible; uninoculated; villous; virus cache: cord-285812-l7dpv6nx.txt plain text: cord-285812-l7dpv6nx.txt item: #90 of 134 id: cord-287182-f0q8gfzc author: Liao, Ji‐ping title: Severe pneumonia caused by adenovirus 7 in pregnant woman: Case report and review of the literature date: 2016-06-21 words: 2082 flesch: 43 summary: Polymerase chain reaction (PCR), nested PCR and gene sequencing of nasopharyngeal aspirates were positive for adenovirus type 7, which was confirmed by more than fourfold elevation of IgG titer of adenovirus type 7 (retrieved from the patient's blood sample stored in the clinical laboratory from hospital day 1 to day 7). However, adenoviral pneumonia in pregnant patients has not been reported before. keywords: adenovirus; adults; azithromycin; blood; care; case; chest; cough; day; days; fetal; fever; healthy; high; i.v; laboratory; min; negative; non; normal; outcomes; oxygen; patient; pneumonia; pregnancy; pregnant; rate; reference; report; respiratory; severe; sputum; vancomycin; women cache: cord-287182-f0q8gfzc.txt plain text: cord-287182-f0q8gfzc.txt item: #91 of 134 id: cord-287520-51kmd2ds author: Carneiro, Arie title: Impact of the COVID-19 Pandemic on the Urologist’s clinical practice in Brazil: a management guideline proposal for low- and middle-income countries during the crisis period date: 2020-05-20 words: 4546 flesch: 42 summary: After the procedure, COVID-19 positive patients should be admitted to the designated areas for suspected and / or confirmed patients with COVID-19, if the institution in question provides such area. While efforts should be directed to the care of COVID-19 patients, other conditions (especially urgencies and oncological cases) must continue to be assisted. keywords: -remove; additional; advanced; association; asymptomatic; available; bladder; cancer; carcinoma; care; cases; chemotherapy; cisplatin; clinical; control; countries; covid-19; crisis; cystectomy; days; disease; follow; gemcitabine; gloves; health; hematuria; high; important; infection; invasive; local; management; metastatic; months; muscle; necessary; negative; neoadjuvant; non; order; outcomes; pandemic; patients; period; possible; prednisone; procedure; prostate; radical; recommendations; renal; resources; risk; rna; stage; stent; study; surgeries; surgery; surgical; survival; symptoms; tract; treatment; turbt; urinary; urology; use; weeks cache: cord-287520-51kmd2ds.txt plain text: cord-287520-51kmd2ds.txt item: #92 of 134 id: cord-288051-wp8v2mc5 author: Sánchez-González, Álvaro title: What Should Be Known by a Urologist About the Medical Management of COVID-19’s Patients? date: 2020-09-01 words: 3624 flesch: 45 summary: The infection and isolation of many physicians reduced its availability to struggle against COVID-19, so it became essential to recruit surgical staff to assist COVID-19 patients. A trial of lopinavir-ritonavir in adults hospitalized with severe Covid-19 A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19 Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19 Pharmacologic treatments for coronavirus disease 2019 (COVID-19) a review COVID-19) outbreak: what the department of radiology should know Compassionate use of remdesivir for patients with severe Covid-19 Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial Effective treatment of severe COVID-19 patients with tocilizumab Why tocilizumab could be an effective treatment for severe COVID -19 ? keywords: activity; acute; ards; assessment; authors; cases; characteristics; clearance; clinical; coronavirus; course; cov-2; covid-19; current; days; dimer; disease; drugs; epidemiology; events; evidence; fees; fever; fig; healthcare; hepatic; hospitalization; illness; increase; infected; infection; inflammatory; kidney; laboratory; level; lung; management; mortality; multidisciplinary; non; onset; oxygen; patients; personal; pneumonia; qtc; respiratory; response; results; review; risk; sars; severe; severity; study; support; symptoms; table; teams; time; tocilizumab; transmission; treatment; urologists; use; viral cache: cord-288051-wp8v2mc5.txt plain text: cord-288051-wp8v2mc5.txt item: #93 of 134 id: cord-291315-y40s45iv author: Logunov, Denis Y title: Safety and immunogenicity of an rAd26 and rAd5 vector-based heterologous prime-boost COVID-19 vaccine in two formulations: two open, non-randomised phase 1/2 studies from Russia date: 2020-09-04 words: 5736 flesch: 45 summary: Thus, the presence of a pre-existing immune response to the components of vaccine vectors rAd26 and rAd5 does not affect the titre of RBD-specific antibodies in the serum of participants. [30] The incidence of adverse events in our studies was slightly lower than in other work; a comparative clinical study with other vaccines is needed to confirm these findings. keywords: adenovirus; adverse; antibodies; antibody; antigen; aug; boost; cell; cellular; clinical; components; convalescent; coronavirus; correlation; cov-2; covid-19; data; days; dose; events; formation; formulations; frozen; gam; gene; glycoprotein; healthy; heterologous; humoral; immune; immunity; immunogenicity; infection; mers; neutralising; non; open; participants; people; phase; plasma; prime; rad26; rad5; randomised; rbd; receptor; recombinant; report; research; respiratory; responses; russia; safety; sars; specific; studies; study; syndrome; test; titres; trial; vaccination; vaccine; vector; viral; volunteers cache: cord-291315-y40s45iv.txt plain text: cord-291315-y40s45iv.txt item: #94 of 134 id: cord-292970-32mql9nq author: Camdessanche, Jean-Philippe title: COVID-19 may induce Guillain-Barré syndrome date: 2020-04-15 words: 300 flesch: 57 summary: This must be known by clinicians as GBS may lead to ICU admission and needs to be differentiated from a possible ICU-acquired weakness after ICU treatments. Clinical presentation was moderate with high grade fever for three days requiring oxygen 2-3 L/min through nasal cannula for five days. keywords: barré; covid-19; days; fever; guillain; icu; infection; sars cache: cord-292970-32mql9nq.txt plain text: cord-292970-32mql9nq.txt item: #95 of 134 id: cord-295086-tc3re52f author: Lu, Guoguang title: Dynamic changes in routine blood parameters of a severe COVID-19 case date: 2020-05-13 words: 1751 flesch: 45 summary: Dynamic changes in routine blood parameters might be helpful for the prognosis of COVID-19 patients and evaluation of the treatment effect. Currently, the number of COVID-19 patients is rapidly increasing worldwide, and some countries and regions, such as Africa, lack medical resources [2] . keywords: admission; blood; cells; changes; condition; covid-19; crp; day; days; diagnosis; disease; dynamic; eosinophils; indicators; lymphocytes; monocytes; neutrophils; nlr; parameters; patient; plr; prognosis; routine; severe; treatment; wbcs cache: cord-295086-tc3re52f.txt plain text: cord-295086-tc3re52f.txt item: #96 of 134 id: cord-295367-xhdki8jn author: McNally, D. title: Rapid relief of acute sore throat with AMC/DCBA throat lozenges: randomised controlled trial date: 2009-10-22 words: 7350 flesch: 48 summary: Methods: Patients (n = 310) were randomly assigned to receive AMC ⁄ DCBA throat lozenges (n = 155) or nonmedicated placebo lozenges (n = 155). The superior analgesic effects and improvements in functional impairment scores observed with AMC ⁄ DCBA throat lozenges translate into pain relief benefits that are clinically meaningful and are thus a suitable OTC treatment option for patients in the self-management of acute sore throat. keywords: active; activities; acute; acute sore; amc; amylmetacresol; analgesic; assessment; auc; baseline; change; data; day; days; dcba throat; difference; difficulty; dose; effects; efficacy; end; events; functional; group; impairment; lozenges; lozenges group; mean; medicated; medication; min; mouth; non; number; overall; pain; pain relief; patients; period; placebo; point; relief; respiratory; scale; scores; severity; significant; sore; sore throat; soreness; strepsils; study; swallowing; symptoms; throat; throat lozenges; throat relief; throat soreness; timepoints; treatment; ⁄ dcba cache: cord-295367-xhdki8jn.txt plain text: cord-295367-xhdki8jn.txt item: #97 of 134 id: cord-295633-vkjcheaz author: Hao, Xin‐yan title: The characteristics of hDPP4 transgenic mice subjected to aerosol MERS coronavirus infection via an animal nose‐only exposure device date: 2019-10-30 words: 5112 flesch: 41 summary: Vector Borne Zoonotic Dis Intranasal influenza infection of mice and methods to evaluate progression and outcome Comparison of traditional intranasal and aerosol inhalation inoculation of mice with influenza A viruses A mouse model for MERS coronavirus-induced acute respiratory distress syndrome Generation of a transgenic mouse model of Middle East respiratory syndrome coronavirus infection and disease Mouseadapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice Distribution of aerosols in mouse lobes by fluorescent imaging Multi-organ damage in human dipeptidyl peptidase 4 transgenic mice infected with middle east respiratory syndrome-coronavirus An acute immune response to Middle East respiratory syndrome coronavirus replication contributes to viral pathogenicity Association of higher MERS-CoV virus load with severe disease and death, Saudi Arabia Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis SARS and other coronaviruses as causes of pneumonia Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment Association between severity of MERS-CoV infection and incubation period Clinical implication of radiographic scores in acute Middle East respiratory syndrome coronavirus pneumonia: report from a single tertiary-referral center of South Korea Mortality rate of ICU patients with the Middle East respiratory syndrome -coronavirus infection at King Fahad Hospital Middle East respiratory syndrome Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study Clinical presentation and outcomes of Middle East respiratory syndrome in the Republic of Korea Clinicopathologic, immunohistochemical, and ultrastructural findings of a fatal case of Middle East respiratory syndrome coronavirus infection in the United Arab Emirates Middle East respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4 A human DPP4-Knockin mouse's susceptibility to infection by authentic and pseudotyped MERS-CoV One Health Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4 Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC A rapid scoping review of Middle East respiratory syndrome coronavirus in animal hosts Clinical and biological character in mouse models for Middle East respiratory syndrome generated by transduction with different doses of DPP4 molecule Elevated human dipeptidyl peptidase 4 expression reduces the susceptibility of hDPP4 transgenic mice to Middle East respiratory syndrome coronavirus infection and disease Acute respiratory infection in human dipeptidyl peptidase 4-transgenic mice infected with Middle East respiratory syndrome coronavirus Emergencies preparedness, response. keywords: acute; aerosol; aerosol group; alveolar; animal; antigen; brain; cells; challenged; changes; clinical; control; coronavirus; cov; days; device; differences; disease; east; east respiratory; endothelial; exposure; figure; group; hdpp4; high; human; immunohistochemical; infected; infection; instillation; instillation group; interstitial; intranasal; lesions; levels; loads; loss; lungs; mers; mers‐cov; mice; middle; middle east; models; moderate; mouse; patients; pneumonia; rate; respiratory; respiratory syndrome; results; severe; significant; slower; staining; survival; syndrome; syndrome coronavirus; tissue; transgenic; viral; weight cache: cord-295633-vkjcheaz.txt plain text: cord-295633-vkjcheaz.txt item: #98 of 134 id: cord-295703-no45mgyd author: ALTAY, O. title: Combined metabolic cofactor supplementation accelerates recovery in mild-to-moderate COVID-19 date: 2020-10-05 words: 3980 flesch: 43 summary: A randomized controlled trial Effects of N-acetylcysteine treatment in acute respiratory distress syndrome: A meta-analysis L-Carnitine preserves endothelial function in a lamb model of increased pulmonary blood flow Acetyl-L-Carnitine Supplementation During HCV Therapy With Pegylated Interferon-α 2b Plus Ribavirin: Effect on Work Performance; A Randomized Clinical Trial Combination of niacin and fenofibrate with lifestyle changes improves dyslipidemia and hypoadiponectinemia in HIV patients on antiretroviral therapy: results of heart positive Serine Metabolism Supports Macrophage IL-1β Production Long-Term l-Serine Administration Reduces Food Intake and Improves Oxidative Stress and Sirt1/NFκB Signaling in the Hypothalamus of Aging Mice Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults Nicotinamide riboside is uniquely and orally bioavailable in mice and humans Extrapulmonary manifestations of COVID-19 Abnormal Liver Tests in COVID-19: A Retrospective Observational Cohort Study of 1827 Patients in a Major U.S. Hospital Network Gastrointestinal, hepatobiliary, and pancreatic manifestations of COVID-19 Prevalence and Characteristics of Gastrointestinal Symptoms in Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in the United States: A Multicenter Cohort Study Abnormal liver function tests in COVID-19 patients: relevance and potential pathogenesis L-Serine Supplementation Attenuates Alcoholic Fatty Liver by Enhancing Homocysteine Metabolism in Mice and Rats Serine Is an Essential Metabolite for Effector T Cell Expansion Combined Treatment with L-Carnitine and Nicotinamide Riboside Improves Hepatic Metabolism and Attenuates Obesity and Liver Steatosis Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity Discoveries of Nicotinamide Riboside as a Nutrient and Conserved NRK Moreover, a large number of clinical trials have been performed for repositioning existing drugs for effective treatment of COVID-19 patients (7, 8) . keywords: adverse; analysis; ast; author; available; carnitine; characteristics; clinical; cmcs; combination; combined; copyright; covid-19; day; days; diseases; doi; figure; funder; group; holder; https://doi.org/10.1101/2020.10.02.20202614; hydroxychloroquine; international; levels; license; liver; medrxiv; metabolic; mild; nicotinamide; october; patients; peer; perpetuity; placebo; preprint; randomization; randomized; recovery; results; review; riboside; safety; serine; significant; standard; study; supplementation; symptoms; table; therapy; time; total; treatment; trial; version cache: cord-295703-no45mgyd.txt plain text: cord-295703-no45mgyd.txt item: #99 of 134 id: cord-299343-gsrgf4dd author: Wilson, A. M. title: Quantifying SARS-CoV-2 infection risk within the Apple/Google exposure notification framework to inform quarantine recommendations date: 2020-07-19 words: 10717 flesch: 43 summary: We report on preliminary calibration to inform infection risk calculated on the receiver's phone. We therefore fit to obtain infection probabilities that are compatible with household spread, where infection risk is relatively well documented, albeit still quite uncertain. keywords: app; approach; asymptomatic; attenuation; author; available; bluetooth; case; close; conditional; contact; copyright; cov-2; covid-19; current; curve; data; date; day; day quarantine; days; different; disease; distance; distribution; dose; duration; exposure; fold; framework; function; funder; future; gaen; health; high; holder; household; incubation; index; individuals; infected; infection; infection risk; infectiousness; inhalation; initial; interaction; international; july; level; license; likely; longer; low; manual; medrxiv; minutes; negative; note; number; onset; order; periods; perpetuity; population; positive; possible; preprint; probability; public; quantitative; quarantine; rate; recommendations; relative; risk; sars; shedding; single; symptoms; testing; threshold; time; total; transmission; transmission risk; use; users; variation; version; viral; virus cache: cord-299343-gsrgf4dd.txt plain text: cord-299343-gsrgf4dd.txt item: #100 of 134 id: cord-300570-xes201g7 author: Patwardhan, J. title: PREDICTIONS FOR EUROPE FOR THE COVID-19 PANDEMICAFTER LOCKDOWN WAS LIFTED USING AN SIR MODEL date: 2020-10-06 words: 5300 flesch: 61 summary: The model fails around 15 days after cases plateau, because we expect cases and deaths to decrease continually until they reach 0, but instead we get a stagnation of the virus. Each stagnation occurs during a period of increased cases. keywords: analysis; author; available; bars; cases; copyright; countries; country; data; day; days; deaths; doi; error; expected; fits; funder; growth; holder; https://doi.org/10.1101/2020.10.03.20206359; increase; international; license; medrxiv; medrxiv preprint; model; number; observed; october; perpetuity; plateau; plot; point; preprint; reopening; residual; time; value; version; virus cache: cord-300570-xes201g7.txt plain text: cord-300570-xes201g7.txt item: #101 of 134 id: cord-300810-a1skdp67 author: Lafay, F. title: Spread of the CVS strain of rabies virus and of the avirulent mutant AvO1 along the olfactory pathways of the mouse after intranasal inoculation date: 1991-07-31 words: 5739 flesch: 50 summary: Infection of the central nervous system and centrifugal spread of virus to peripheral tissues Two anatomically specific classes of candidate cholinoceptive neurons in the rat olfactory bulb The Rat Brain in Stereotaxic Coordinates Spread of a neurotropit murine coronavirus into the CNS via the trigeminal and olfactory nerves Antigenic site II of the rabies glycoproteln: Structure and role in viral virulence Laminar distributions of interneurons in the main olfactory bulb of adult hamster Rabies virus virulence: Effect on pathogenicity and sequence characterization of mutations affecting antigenic site Ill of the glycoprotein Transport of molecules from nose to brain: Transneuronal anterograde and retrograde labeling in the rat olfactory system by wheat germ agglutinin-horseradish peroxidase applied to the nasal epithelium Surprisingly rich projection from locus coeruleus to the olfactory bulb in the rat Olfactory system An in viva and in vitro study of rabies virus infection of the rat superior cervical ganglia Arginine or lysine in position 333 of ERA and CVS glycoprotein is necessary for rabies virulence in adult mice The role of protetns in vesicular stomatitis virus replication. The ratio between infected cells and PFU is the same for both viruses and the infected cells were found in the same epithelial areas (data not shown). keywords: a/.; able; animals; antigenic; aon; avirulent; avol; brain; bulb; cells; cns; contralateral; cvs; cycle; day; days; early; epithelium; fig; glycoprotein; hdb; horizontal; infected; infected cells; infection; inoculation; instillation; layer; mice; mitral; mitral cells; mob; mouse; mutant; nasal; neurons; nuclei; nucleus; number; olfactory; p.i; pathways; pbs; permissive; pfu; rabies; rabies virus; rat; receptor; receptor cells; route; sections; site; spread; strain; system; trigeminal; type; viral; virus; viruses; wild cache: cord-300810-a1skdp67.txt plain text: cord-300810-a1skdp67.txt item: #102 of 134 id: cord-301947-b6nwaost author: Millán-Oñate, José title: Successful recovery of COVID-19 pneumonia in a patient from Colombia after receiving chloroquine and clarithromycin date: 2020-04-24 words: 3712 flesch: 45 summary: Even, there is a lack of case reports of COVID-19 patients recovering from SARS-CoV-2 infection [21, 22] . In Colombia, the Ministry of Health and the Colombian Association of Infectious Diseases [38] , have considered the possible use of chloroquine for COVID-19 patients, in those hospitalized under close medical observation, as was our case. keywords: admission; antiviral; azithromycin; blood; case; cauca; china; chloroquine; clarithromycin; clinical; colombia; confirmed; coronavirus; cough; cov-2; covid-19; day; days; disease; drugs; efficacy; fever; glass; ground; guidelines; health; hydroxychloroquine; infection; italy; leukopenia; march; negative; normal; novel; opacities; pandemic; patient; pcr; peripheral; pneumonia; protein; public; randomized; respiratory; results; rrt; sars; spain; studies; study; symptoms; table; therapeutical; treatment; trials; use; valle cache: cord-301947-b6nwaost.txt plain text: cord-301947-b6nwaost.txt item: #103 of 134 id: cord-303878-v2n9jeeb author: Stiles, Jonathan title: Working at home and elsewhere: daily work location, telework, and travel among United States knowledge workers date: 2020-09-05 words: 7668 flesch: 45 summary: However Lachapelle et al. (2017) used Canadian time use data to explore the relationship of working from different locations with travel, finding that some patterns of working from home were associated with less overall travel, a decreased likelihood of traveling at peak travel times, and an increased likelihood of using a non-motorized form of transport. For the purpose of this analysis, peak travel times are defined as being 6 a.m. to 9 a.m. in the morning and 4 p.m. to 7 p.m. in the evening, although other levels were tried yielding similar findings. keywords: a.m.; activities; activity; alternate; american; analysis; avoidance; categories; commute; computing; daily; data; day; demand; departure; differences; different; discretionary; duration; effect; employees; evening; findings; flexibility; higher; home; homeworkers; homeworking; hour; hour travel; individuals; knowledge; likelihood; likely; location; maintenance; management; mobile; models; morning; multiple; non; office; participation; patterns; peak; peak hour; period; purposes; related; relationship; research; results; single; states; study; survey; survival; table; telecommuting; telework; time; transportation; travel; travel time; trend; united; use; variables; vehicle; work; work location; workday; workers; working; workplace cache: cord-303878-v2n9jeeb.txt plain text: cord-303878-v2n9jeeb.txt item: #104 of 134 id: cord-304562-5xh4p786 author: Tanabe, Naoya title: Dupilumab maintenance therapy in an asthmatic patient with coronavirus disease 2019 pneumonia date: 2020-11-07 words: 668 flesch: 45 summary: On day12, chest 51 computed tomography (CT) showed bilateral peripheral-dominant ground glass 52 opacity (GGO) and consolidation ( Fig. 2A) , and because he had several risk 53 factors for severe COVID-19 including obesity and diabetes, he was transferred 54 to intensive care unit at our hospital and received oxygen therapy via face mask 55 (5-6 L/min). He was gradually recovered, a negative PCR for 62 SARS-CoV-2 was confirmed on day 27, oxygen therapy was discontinued on 63 day 28. keywords: ace2; associated; asthma; cells; cov-2; covid-19; day; disease; dupilumab; oxygen; pandemic; respiratory; sars; severe; therapy cache: cord-304562-5xh4p786.txt plain text: cord-304562-5xh4p786.txt item: #105 of 134 id: cord-305365-50uojtet author: Easson, Will title: A review of rabbit and rodent production medicine date: 2001-07-31 words: 5421 flesch: 54 summary: Coccidia (Eimeria spp) can cause diarrhea in young rabbits. Postmortem findings include watery intestinal contents, and E.coli is cultured from the intestinal contents (not a normal finding in the flora in young rabbits). keywords: affected; age; animals; breeding; cage; cause; clinical; colony; common; conception; condition; culture; days; death; diagnosis; diet; disease; doe; environmental; estrus; factors; females; fertility; food; guinea; hamsters; high; hours; infection; lactation; large; light; litter; low; male; management; maternal; mating; medicine; mice; months; neonatal; numbers; old; output; parturition; period; pet; pigs; postpartum; pregnancy; problem; production; protein; pups; rabbits; rate; rats; respiratory; signs; size; small; sows; stock; system; treatment; virus; water; weaning; weeks; year; young cache: cord-305365-50uojtet.txt plain text: cord-305365-50uojtet.txt item: #106 of 134 id: cord-306705-adshd3jj author: Lenander-Lumikari, Marianne title: Effects of the common cold and intranasal fluticasone propionate treatment on mucosal host defense assessed by human saliva()()() date: 2005-11-04 words: 2906 flesch: 49 summary: Salivary neutralizing activity against herpes simplex virus type 1 Inhibition of herpes simplex virus type 1, respiratory syncytial virus and echovirus type 11 by peroxidase-generated hypothiocyanite Effects of human salivas on recombinant HIV-1 proteins Anti-infectivity activity of human salivary secretions toward human immunodeficiency virus Common cold: effects of intranasal fluticasone propionate treatment Viruses and bacteria in the etiology of the common cold Protein measurement with the folin phenol reagent Sensitive immunometric assays for secretory peroxidase and myeloperoxidase in human saliva Isolation procedure and some properties of myeloperoxidase from human leukocytes Purification and characterization of human salivary peroxidase A rapid and sensitive noncompetitive avidin-biotin assay for lactoferrin Immunoglobulins and innate factors of immunity of children prone to respiratory infections Human secretory immunoglobulins, I: salivary secretions from individuals with normal or low levels of serum immunoglobulins Longitudinal study of parotid saliva in HIV-1 infection Nonspecific oral immunity in individuals with HIV infection Nieuw Amerongen AV. No statistical differences could be found between the groups with respect to salivary flow rates or innate salivary defense factors, such as lysozyme, lactoferrin, myeloperoxidase, and salivary peroxidase (Table II) . keywords: .01; .05; cold; common; common cold; day; days; defense; effect; factors; flow; fluticasone; group; host; human; iga; igg; innate; lactoferrin; lysozyme; medication; mucosal; oral; patients; peroxidase; propionate; protein; rate; relative; salivary; study; symptoms; table; total; treatment; virus; viruses cache: cord-306705-adshd3jj.txt plain text: cord-306705-adshd3jj.txt item: #107 of 134 id: cord-309588-kw4d32dt author: Chan, Michael H.M. title: Steroid-induced osteonecrosis in severe acute respiratory syndrome: a retrospective analysis of biochemical markers of bone metabolism and corticosteroid therapy date: 2006-06-30 words: 4625 flesch: 40 summary: We have shown that there has been a close temporal relationship between the serial changes in serum biochemical bone markers in SARS patients and pulse corticosteroid therapy. Various risk factors for the development of osteonecrosis were assessed using receiver operating characteristics curve comparison with appropriate test statistics and Spearman’s coefficients of rank correlation with biochemical bone markers. keywords: acute; admission; balp; baseline; biochemical; bone; clinical; cohort; concentrations; corticosteroid; ctx; daily; day; development; diagnosis; dosage; dose; effect; equivalent; factors; fever; formation; health; high; hong; hospital; hydrocortisone; increase; knee; kong; maintenance; marked; markers; median; metabolism; methylprednisolone; mri; onset; osteocalcin; osteonecrosis; patients; prevalence; pulse; resorption; respiratory; risk; samples; sars; serum; severe; significant; study; subsequent; syndrome; therapy; time; use; weighted cache: cord-309588-kw4d32dt.txt plain text: cord-309588-kw4d32dt.txt item: #108 of 134 id: cord-310249-cvv77f10 author: Yule, Terecita D. title: Canine parvovirus vaccine elicits protection from the inflammatory and clinical consequences of the disease date: 1997-05-31 words: 4614 flesch: 39 summary: Clinical scores significantly correlated (PcO.05) with both a-1AG (r=0.54) and SAA (rz0.78) on day 5 and similarly on day 7. Using cell specific antibodies and flow cytometric analysis, a mean of 88% of leukocytes in peripheral Days Post CPV-2 Challenge blood were positively identified as T-cells (CD4+ and CD@, pan-T), B-cells, monocytes, and neutrophils when compared to the absolute leukocyte count obtained conventionally. To visualize virus infected cells, the monolayers were fixed with 80% acetone, then reacted with a monoclonal antibody (mab) (1:lOOOO) specific for the major capsid protein (VPl), followed by fluorescein conjugated anti-murine IgG (Kierkegaard and Perry International, Gaithersburg, MD). keywords: a-1ag; acute; amyloid; analysis; antibodies; antibody; blood; canine; cd4; cells; challenge; changes; clinical; controls; count; cpv-2b; cytometric; data; day; days; differential; disease; efficacy; elevated; experimental; expression; figure; flow; group; human; increase; infection; intensity; laboratory; leukocyte; levels; lymphocytes; lymphopenia; manual; mean; natural; neutropenia; neutrophils; nonvaccinated; observation; observed; parameters; parvovirus; period; phase; post; proteins; puppies; puppy; response; saa; samples; scores; serum; shed; significant; signs; specific; study; titers; trafficking; vaccinates; vaccination; vaccine; values; virus cache: cord-310249-cvv77f10.txt plain text: cord-310249-cvv77f10.txt item: #109 of 134 id: cord-314235-08z2jyzd author: Matzinger, P. title: Strong impact of closing schools, closing bars and wearing masks during the Covid-19 pandemic: results from a simple and revealing analysis date: 2020-09-28 words: 5932 flesch: 58 summary: Each of these measures brought the infection rates down by twofold, for a cumulative reduction of fourfold in new infection rates. This suggests that 40 closing (and re-opening) settings that might not be conducive to social distancing has more impact on new infection rates than would opening other types of businesses (dog groomers, markets, hardware stores; even restaurants). keywords: article; author; available; bars; cases; change; closed; closing; copyright; daily; data; days; deaths; doubling; drop; early; effect; figure; funder; government; holder; hospitalizations; infection; initial; interventions; later; license; mandates; march; masks; medrxiv; new; opening; peer; perpetuity; post; preprint; rates; restaurants; review; schools; september; slopes; states; subject; times; total; usc; version; wearing; work cache: cord-314235-08z2jyzd.txt plain text: cord-314235-08z2jyzd.txt item: #110 of 134 id: cord-317347-by8albr9 author: van Ginkel, Frederik W. title: Age-dependent immune responses and immune protection after avian coronavirus vaccination date: 2015-05-28 words: 5815 flesch: 50 summary: These data strongly support IBV vaccination after day 7 post hatch. To determine whether age of IBV vaccination affected the humoral immune response, plasma samples were collected 14 and 21 days and tears 14 days after vaccination with 3 × 10 5 EID 50 of a live-attenuated ArkDPI IBV vaccine strain on 1, 7 14, 21 or 28 days of age. keywords: age; age group; antibodies; antibody; avian; avidity; birds; bronchitis; cells; challenge; chickens; chicks; control; data; day; days; delay; dependent; different; early; elisa; field; fig; goblet; group; higher; ibv; iga; igg; igm; immune; immunity; index; industry; infectious; lack; levels; life; lower; lymphoid; maternal; mean; mucosal; natural; old; older; plasma; post; poultry; protection; respiratory; response; samples; significant; specific; spf; strain; supplemental; system; tears; test; titers; tracheal; vaccinated; vaccination; vaccine; virus; week cache: cord-317347-by8albr9.txt plain text: cord-317347-by8albr9.txt item: #111 of 134 id: cord-318994-1xngjndu author: Lier, Audun J. title: Case Report: Disseminated Strongyloidiasis in a Patient with COVID-19 date: 2020-08-14 words: 1971 flesch: 38 summary: This report describes the clinical features of a case of disseminated strongyloidiasis infection and polymicrobial bacteremia in an individual who received immunosuppressive treatment for COVID-19. We report a case of a COVID-19 patient who developed disseminated strongyloidiasis following treatment with high-dose corticosteroids and tocilizumab. keywords: absolute; addition; blood; case; cell; clinical; corticosteroids; count; covid-19; culture; day; days; dose; ecuador; eosinophil; fever; gram; hospital; immunosuppressive; infection; intravenous; ivermectin; larvae; meningitis; negative; patients; repeat; report; risk; sars; serology; sputum; stercoralis; stool; strongyloides; strongyloidiasis; tocilizumab; treatment cache: cord-318994-1xngjndu.txt plain text: cord-318994-1xngjndu.txt item: #112 of 134 id: cord-319933-yp9ofhi8 author: Ruiz, Sara I. title: Chapter 38 Animal Models of Human Viral Diseases date: 2013-12-31 words: 28862 flesch: 41 summary: Wild-type C57BL/6 adult mice are not permissive to chikungunya virus infection by intradermal inoculation. [Comparative Study Research Support Characterization of clinical and immune response in a rotavirus diarrhea model in suckling Lewis rats Development of a heterologous model in germfree suckling rats for studies of rotavirus diarrhea Studies of oral rehydration solutions in animal models Induction of mucosal immune responses and protection against enteric viruses: rotavirus infection of gnotobiotic pigs as a model Developmental immunity in the piglet Swine in biomedical research Neonatal calf diarrhea induced by rotavirus Characterisation of the primary local and systemic immune response in gnotobiotic lambs against rotavirus infection Experimental infection of non-human primates with a human rotavirus isolate Development of a rotavirus-shedding model in rhesus macaques, using a homologous wild-type rotavirus of a new P genotype Reflections on 30 years of AIDS HIVs and their replication The utility of the new generation of humanized mice to study HIV-1 infection: transmission, prevention, pathogenesis, and treatment Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice Hematopoietic stem cell-engrafted NOD/ SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses HIV-1 infection and CD4 T cell depletion in the humanized Rag2Ã�/Ã� gamma cÃ�/Ã� (RAG-hu) mouse model HIV-1 infection and pathogenesis in a novel humanized mouse model Induction of robust cellular and humoral virusspecific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4(þ) T cell decline in humanized mice Mucosal immunity and vaccines Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1 Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus Limited dissemination of pathogenic SIV after vaginal challenge of rhesus monkeys immunized with a live Virulence and reduced fitness of simian immunodeficiency virus with the M184V mutation in reverse transcriptase SIV-induced impairment of neurovascular repair: a potential role for VEGF Therapeutic DNA vaccine induces broad T cell responses in the gut and sustained protection from viral rebound and AIDS in SIV-infected rhesus macaques A Nonfucosylated variant of the anti-HIV-1 monoclonal antibody b12 has enhanced FcgammaRIIIamediated antiviral activity in vitro but does not improve protection against mucosal SHIV challenge in macaques A trivalent recombinant Ad5 gag/pol/nef vaccine fails to protect rhesus macaques from infection or control virus replication after a limiting-dose heterologous SIV challenge Animal model for the therapy of acquired immunodeficiency syndrome with reverse transcriptase inhibitors Susceptibility of HIV-2, SIV and SHIV to various anti-HIV-1 compounds: implications for treatment and postexposure prophylaxis Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection SHIV-1157i and passaged progeny viruses encoding R5 HIV-1 clade C env cause AIDS in rhesus monkeys Update on animal models for HIV research Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission Vpx is Critical for SIVmne infection of pigtail macaques Impact of short-term HAART initiated during the chronic stage or shortly post-exposure on SIV infection of male genital organs The rhesus macaque pediatric SIV infection modeld a valuable tool in understanding infant HIV-1 pathogenesis and for designing pediatric HIV-1 prevention strategies Perinatal transmission of SHIV-SF162P3 in Macaca nemestrina Immune and genetic correlates of vaccine protection against mucosal infection by SIV in monkeys Chronic administration of tenofovir to rhesus macaques from infancy through adulthood and pregnancy: summary of pharmacokinetics and biological and virological effects Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the step study): a double-blind, randomised, placebo-controlled, test-of-concept trial Human papillomavirus in cervical cancer Human papillomavirus research: do we still need animal models? Animal models of papillomavirus pathogenesis Evidence of human papillomavirus vaccine effectiveness in reducing genital warts: an analysis of California public family planning administrative claims data The rabbit viral skin papillomas and carcinomas: a model for the immunogenetics of HPV-associated carcinogenesis Protection of beagle dogs from mucosal challenge with canine oral papillomavirus by immunization with recombinant adenoviruses expressing codon-optimized early genes Naturally occurring, nonregressing canine oral papillomavirus infection: host immunity, virus characterization, and experimental infection Regression of canine oral papillomas is associated with infiltration of CD4þ and CD8þ lymphocytes Characterization and experimental transmission of an oncogenic papillomavirus in female macaques A multimeric L2 vaccine for prevention of animal papillomavirus infections Preclinical development of highly effective and safe DNA vaccines directed against HPV 16 E6 and E7 US doctors investigate more than 50 possible cases of monkeypox Isolation of monkeypox virus from wild squirrel infected in nature Reemergence of monkeypox: prevalence, diagnostics, and countermeasures Human monkeypox infection: a family cluster in the midwestern United States Human monkeypox and other poxvirus infections of man The confirmation and maintenance of smallpox eradication Human monkeypox Identification of wild-derived inbred mouse strains highly susceptible to monkeypox virus infection for use as small animal models A prairie dog animal model of systemic orthopoxvirus disease using west African and Congo Basin strains of monkeypox virus Comparison of monkeypox viruses pathogenesis in mice by in vivo imaging Comparative pathology of North American and central African strains of monkeypox virus in a ground squirrel model of the disease Experimental infection of an African dormouse (Graphiurus kelleni) with monkeypox virus A mouse model of lethal infection for evaluating prophylactics and therapeutics against monkeypox virus Experimental infection of ground squirrels (Spermophilus tridecemlineatus) with monkeypox virus Experimental infection of prairie dogs with monkeypox virus Experimental infection of cynomolgus macaques (Macaca fascicularis) with aerosolized monkeypox virus The pathology of experimental aerosolized monkeypox virus infection in cynomolgus monkeys (Macaca fascicularis) Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox Smallpox vaccine does not protect macaques with AIDS from a lethal monkeypox virus challenge Smallpox vaccine-induced antibodies are necessary and sufficient for protection against monkeypox virus Virulence and pathophysiology of the Congo Basin and west African strains of monkeypox virus in non-human primates keywords: able; activity; acute; adapted; adult; aerosol; african; age; aids; analysis; animal; animal models; anorexia; antibodies; antibody; antiviral; asymptomatic; attenuated; avian; b virus; balb; bats; birds; blood; brain; cases; cause; cells; central; challenge; changes; characterization; characterized; chikungunya; children; chimpanzees; chronic; clinical; clinical disease; clinical signs; cns; common; comparative; congo; contact; coronavirus; cotton; course; cov; cov infection; crimean; cynomolgus; damage; days; death; dengue; dengue virus; dependent; develop; development; diarrhea; different; disease; disease model; distribution; dogs; dose; drug; early; ebov; eeev; effective; efficacy; encephalitis; encephalitis virus; encephalomyelitis; enzymes; equine; experimental; experimental infection; exposure; failure; fatal; fatality; features; ferrets; fever; fever virus; filovirus; form; guinea; h5n1; hamsters; hantavirus; health; heart; hemorrhagic; hendra; hendra virus; hepatitis; high; histopathological; hiv; hiv-1; horses; host; human; human disease; human infection; illness; immune; immunity; important; individuals; induced; infant; infected; infection; infection model; inflammation; influenza; influenza infection; influenza virus; initial; inoculation; interferon; interstitial; intracerebral; intranasal; intraperitoneal; intratracheal; involvement; isolate; knockout; laboratory; lack; lassa; lesions; lethal; lethality; lethargy; levels; like; limited; liver; loss; low; lower; lungs; lymph; macaca; macaques; major; manifestations; marmosets; mice; mild; model; monkeypox; monkeypox virus; monkeys; mortality; mosquitoes; mouse; mouse model; mpxv; mucosal; natural; necrosis; nervous; neurological; new; nhps; nile; nile virus; nipah; nipah virus; nodes; nonhuman; norovirus; novel; number; old; onset; oral; outbreak; papillomavirus; paralysis; passaged; pathogenesis; pathogenic; pathology; patients; period; peripheral; person; phase; pigs; pneumonia; pneumonitis; poliovirus; possible; postexposure; postinfection; potential; present; prevention; primary; primates; progression; protection; pulmonary; rabies; rabies virus; range; rate; rats; receptor; recombinant; related; replication; reported; research; respiratory; respiratory disease; response; responsible; results; rhesus; rhesus macaques; rift; role; rotavirus; route; sars; severe; severe disease; shedding; signs; similar; siv; small; smallpox; species; spleen; spread; states; strains; studies; study; subcutaneous; susceptibility; susceptible; symptoms; syncytial; syncytial virus; syndrome; syrian; system; test; testing; therapeutics; time; tissues; tract; transmission; treatment; type; understanding; united; upper; useful; vaccine; vaginal; valley; veev; venezuelan; viral; viremia; virulence; virus; virus experimental; virus infection; virus pathogenesis; viruses; weeks; weev; weight; west; western; wild; wnv; world; years; young cache: cord-319933-yp9ofhi8.txt plain text: cord-319933-yp9ofhi8.txt item: #113 of 134 id: cord-324345-j43rpvwk author: Leong, Hoe Nam title: SARS – My personal battle date: 2010-11-19 words: 3112 flesch: 68 summary: The next day was the weekly scheduled infectious disease round in my practicing hospital, TTSH, where infectious disease physicians from the various public hospitals in Singapore would gather. It was easily 12 midnight in Singapore time when I woke up my colleague! keywords: acute; agent; air; atypical; battle; better; cough; day; diagnosis; disease; doctor; evening; fever; flight; frankfurt; hand; home; hong; hospital; illness; infectious; isolation; law; main; mother; new; news; patient; physician; pneumonia; respiratory; sars; severe; sgh; singapore; symptoms; syndrome; time; trip; ttsh; unwell; wife cache: cord-324345-j43rpvwk.txt plain text: cord-324345-j43rpvwk.txt item: #114 of 134 id: cord-324553-qd8249w3 author: Cadegiani, F. A. title: An open-label prospective observational study of antiandrogen and non-antiandrogen early pharmacological approaches in females with mild-to-moderate COVID-19. The Pre-AndroCoV Female Trial. date: 2020-10-06 words: 6396 flesch: 38 summary: The replication of a highly sensitive case-detection guidance that include the occurrence of absolutely any symptom as being suspected for COVID-19 may find barriers that may preclude from a successful approach, including: 1. Lack of general and medical education regarding the unspecific pattern of COVID-19 clinical presentation; 2. Self-judgement of not being affected by COVID-19; 3. Patients were assessed for COVID-19 clinical course, clinical and viral duration, and disease progression. keywords: additional; ageusia; anosmia; antiviral; approaches; author; clinical; complications; copyright; copyright holder; cov-2; covid-19; days; detection; differences; disease; doi; dry; duration; early; effective; females; fever; funder; groups; ha females; holder; https://doi.org/10.1101/2020.10.05.20206870; hydroxychloroquine; lack; license; medrxiv; medrxiv preprint; non; number; october; outcomes; pain; patients; peer; peer review; pharmacological; preprint; present; presentation; review; risk; rtpcr; sars; severe; similar; specific; spironolactone; study; symptoms; syndrome; table; time; users; version cache: cord-324553-qd8249w3.txt plain text: cord-324553-qd8249w3.txt item: #115 of 134 id: cord-326143-6ndqgxy8 author: Wang, Qiang title: Successful recovery of severe COVID-19 with cytokine storm treating with extracorporeal blood purification date: 2020-05-26 words: 1328 flesch: 52 summary: (198.66 pg/ml) was almost 10 folds of normal range (≤5.9 pg/ml) which indicated an initiation of cytokine storm on day 12 ( Figure 1 ). He got fever on day 1 (February 14, 2020) and had chill, headache, muscle soreness, fatigue, nausea, cough, and chest distress and shortness of breath on day 3. keywords: blood; chest; clinical; covid-19; cytokine; day; distress; ebp; min; normal; oxygen; patients; plasma; range; respiratory; sars; storm; supplemental; ventilation cache: cord-326143-6ndqgxy8.txt plain text: cord-326143-6ndqgxy8.txt item: #116 of 134 id: cord-327045-hn8pmcto author: Li, Yao title: Quercetin, Inflammation and Immunity date: 2016-03-15 words: 5377 flesch: 35 summary: In the Suihua area of northern China, quercetin intake was reported to be 4.37 mg/day, where the main food sources of flavonol was apples (7.4%), Quercetin (C15H10O7) is an aglycone, lacking an attached sugar. In the Suihua area of northern China, quercetin intake was reported to be 4.37 mg/day, where the main food sources of flavonol was apples (7.4%), followed by potatoes (3.9%), lettuce (3.8%) and oranges (3.8%) keywords: absorption; acid; action; activity; aglycone; animals; anti; antioxidant; apples; attached; berries; bioavailability; blood; cells; concentration; cord; day; derivatives; dietary; different; effect; enzymes; exercise; experimental; expression; flavonoid; flavonols; food; form; fruits; function; glycoside; glycosyl; group; health; human; immune; immunity; induced; inflammation; inflammatory; influence; inhibition; injury; intake; intestine; kinase; levels; liver; main; major; mast; metabolism; metabolites; mice; mitochondrial; onions; oxidative; performance; placebo; plant; plasma; production; properties; protein; quercetin; rats; results; small; sources; studies; study; subjects; sugar; supplementation; tea; tomatoes; type; vegetables; vivo; water; weeks cache: cord-327045-hn8pmcto.txt plain text: cord-327045-hn8pmcto.txt item: #117 of 134 id: cord-330414-yh58ya39 author: Agarwal, Deepak K. title: Catheter Removal on the Same Day of Holmium Laser Enucleation of the Prostate: Outcomes of a Pilot Study date: 2020-10-10 words: 2603 flesch: 42 summary: However, despite these limitations this study is the first to demonstrate the feasibility and high success rate of same day catheter removal after HoLEP. Same day catheter removal after HoLEP is feasible and safe in selected patients, making the procedure truly minimally invasive for the patients. We sought to determine if these technical and technological advancements would allow for successful same day catheter removal after HoLEP. After obtaining Institutional Review Board approval, we performed a retrospective review of patients undergoing HoLEP who underwent same day catheter removal at our institution by three surgeons from November 2019 through March 2020. keywords: bph; case; catheter; clinic; cohort; day; discharge; enucleation; feasible; holep; holmium; hospital; iqr; laser; median; outcomes; outpatient; patients; pod1; postoperative; preoperative; procedure; prostate; rate; removal; size; study; success; surgery; time; trial; turp; urinary; voiding; volume cache: cord-330414-yh58ya39.txt plain text: cord-330414-yh58ya39.txt item: #118 of 134 id: cord-331347-imexhlwn author: Anzai, Asami title: Assessing the Impact of Reduced Travel on Exportation Dynamics of Novel Coronavirus Infection (COVID-19) date: 2020-02-24 words: 4482 flesch: 51 summary: The cumulative number of exported COVID-19 cases observed in the former scenario is denoted m, To estimate the reduced volume of exported cases, we employ a counterfactual model. Supposing that h(t) is the observed number of cases on day t, the reduced travel volume of exported cases by Day 67 is calculated as: . keywords: cases; china; contacts; coronavirus; covid-19; data; day; days; delay; epidemic; epidemiological; exponential; figure; growth; impact; infected; january; japan; lockdown; major; major epidemic; movement; novel; number; observed; probability; reduced; reduction; restrictions; study; time; transmission; travel; travel volume; volume; wuhan cache: cord-331347-imexhlwn.txt plain text: cord-331347-imexhlwn.txt item: #119 of 134 id: cord-333522-zsdymkjd author: Gruse, Jeannine title: Quercetin Feeding in Newborn Dairy Calves Cannot Compensate Colostrum Deprivation: Study on Metabolic, Antioxidative and Inflammatory Traits date: 2016-01-11 words: 7029 flesch: 41 summary: Although quercetin is known to exert antioxidative effects, we did not find improved antioxidative status in the plasma of calves nor increased hepatic expression of antioxidative enzymes, which is in line with previous findings of our group in research conducted on neonatal calves and lactating dairy cows The aim of this work was to study effects of quercetin feeding on metabolic, antioxidative and inflammatory parameters in neonatal calves to investigate whether quercetin could compensate for insufficient colostrum supply. keywords: abundances; acute; age; aglycone; amyloid; antioxidant; antioxidative; assay; bioavailability; birth; blood; body; bovine; calf; calves; capacity; cholesterol; colostrum; complete; concentrations; cortisol; cows; dairy; data; day; days; detection; dietary; differences; disease; effects; expression; factors; fed; feeding; fibrinogen; fig; flavonol; formula; forq+; gastrointestinal; genes; germany; glucagon; glucose; groups; haptoglobin; health; hepatic; higher; igm; immune; immunity; immunoglobulins; inflammation; inflammatory; insulin; intake; intestinal; isoprostanes; life; local; mean; metabolic; metabolites; milk; mrna; neonatal; newborn; oral; oxygen; parameters; passive; performance; phase; plasma; plasma concentrations; previous; procedure; protein; quercetin; rate; reactive; serum; species; status; stress; studies; study; system; table; temperature; tnf; total; weight cache: cord-333522-zsdymkjd.txt plain text: cord-333522-zsdymkjd.txt item: #120 of 134 id: cord-334667-0cah15lg author: Arabi, Yaseen M. title: Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial date: 2020-01-03 words: 3838 flesch: 45 summary: To overcome these challenges, we designed the MIRACLE trial as a recursive two-stage adaptive trial, which is a relatively new method for group sequential trials The trial is designed as a recursive, two-stage, group sequential randomized trial. keywords: additional; adverse; analysis; calculated; care; clinical; combination; data; days; design; efficacy; enrollment; events; file; free; group; guidelines; interferon; interim; lopinavir; mechanical; mers; miracle; miracle trial; number; outcome; patients; primary; protocol; randomization; randomized; recursive; report; respiratory; ritonavir; sample; sequential; size; stage; standard; statistical; study; table; test; therapy; time; treatment; trial; value; ventilation; β1b cache: cord-334667-0cah15lg.txt plain text: cord-334667-0cah15lg.txt item: #121 of 134 id: cord-335490-p63qlcnx author: Schenk, Thomas title: Disseminated Bocavirus Infection after Stem Cell Transplant date: 2007-09-17 words: 1932 flesch: 41 summary: However, rhinitis, cough, and lowgrade fever (<38.5°C) persisted until day 50 (online Appendix Figure) , and HBoV DNA was detected in NPAs on days 37 and 44 at 2.4 × 10 11 and 1.3 × 10 14 copies/mL, respectively (online Appendix Figure) . Subsequent plasma (days 61, 68, 75, 88, 219), NPA (day 219), and stool (day 219) samples were negative for HBoV DNA. keywords: appendix; blood; bocavirus; body; case; children; copies; day; days; disease; dna; drug; figure; hbov; health; hps; hsct; human; infection; isoniazid; levels; load; lower; marrow; negative; normal; npa; npas; online; patient; pcr; prca; report; respiratory; results; samples; tract; treatment; viral cache: cord-335490-p63qlcnx.txt plain text: cord-335490-p63qlcnx.txt item: #122 of 134 id: cord-335975-m6lkrehi author: None title: Proceedings of Réanimation 2018, the French Intensive Care Society International Congress date: 2018-02-05 words: 89523 flesch: 50 summary: The aim of this study was to compare the outcome of ICU patients having received carbapenems to those having received a carbapenem-sparing agent (CSA). Conclusion: Severe hypoxemia, independently from ARDS, worsens the prognosis of ICU patients. keywords: abdominal; absence; acidosis; acinetobacter; activity; acute; acute respiratory; addition; adequate; administration; admission; adult patients; adverse; aeruginosa; age; aged; agreement; aim; airway; aki; albumin; alive; alveolar; amikacin; amoxicillin; analysis; anesthesia; animals; antibiotic; anticoagulation; antifungal; antimicrobial; application; approach; appropriate; ards patients; area; arf; arrest; arterial; assessment; associated; association; august; aureus; available; average; bacterial; balance; baseline; bed; beds; benefit; beta; better; biological; bleeding; blood; body; brain; breastfeeding; breathing; bsi; bup; burned; calcium; cancer; carbapenems; carbon; cardiac; cardiogenic; cardiovascular; care; care unit; caregivers; cases; catheter; cause; cells; center; center study; central; challenge; changes; characteristics; chest; children; choice; chronic; cicu; circulatory; cirrhotic patients; citrate; ckd; classification; clearance; clinical; cohort; collected; coma; comatose patients; combination; comfort; common; comorbidities; compare; comparison; compliance; complications; concentration; conclusion; condition; consciousness; consecutive patients; consumption; context; continuous; control; control patients; conventional; copd; copd patients; correlated; correlation; countries; cranial; creatinine; criteria; critical; crrt; csa; culture; current; curve; cypd; daily; data; database; day mortality; days; death; december; decision; decrease; deficiency; definition; delayed; delirium; delivery; delta; demographic; department; descriptive; development; device; diabetes; diagnosis; dialysis; diameter; diaphragmatic; differences; different; difficult; digestive; discharge; discussion; disease; disorders; distress; distribution; dose; dosing; driving; drug; duration; dysfunction; dzp; early; ecco2r; echocardiography; ecls; ecmo; eeg; effective; effects; efficacy; efl; elderly; eligible; eligible patients; emergency; empirical; encephalopathy; end; endothelial; endpoint; epidemiological; estimated; events; evolution; exacerbation; experience; exposure; expression; extracorporeal; factors; failure; family; fatal; favorable; features; fig; findings; fio; fio2; flow; fluid; follow; france; free; french; frequency; frequent; functional; gastric; general; glasgow; global; glucose; gnb; good; gram; greater; group; guidelines; h24; half; hand; head; health; healthcare; heart; help; hemodynamic; heparin; higher; history; hla; home; hospital; hospital mortality; hospitalization; hour; hus; hypotension; hypothermia; hypoxemia; hypoxemic patients; icu; icu admission; icu discharge; icu length; icu mortality; icu patients; icu stay; icus; identification; ill; imaging; imipenem; immune; impact; implementation; important; improve; improvement; incidence; increased; independent; index; indications; infected; infection; information; infusion; initial; initiation; injury; insertion; insufficient; intensive; intensive care; international; interquartile; intervention; intestinal; intoxication; intravenous; introduction; intubated; intubation; invasive; iqr; isolated; ivc; january; july; june; ketoacidosis; kidney; knowledge; known; lack; lactam; lactate; large; laryngoscope; leading; length; level; life; likely; limitation; limited; linear; literature; liver; local; logistic; long; loss; low; lower; lps; lst; lung; main; major; majority; male; management; maternal; mean; measurements; mechanical; mechanical ventilation; median; medical; medical icu; metabolic; methods; mice; microbiological; mild; min; mixed; mmhg; mmol; model; moderate; monitoring; monocentric; monocentric study; monocytes; months; morbidity; mortality; mortality rate; multiple; multivariate; music; n =; need; negative; neurological; neutrophils; new; nipei; niv; nlr; non; norepinephrine; nosocomial; number; nurses; objective; observational; observational study; observed; occurrence; ohca; ohca patients; old; onset; open; optimal; oral; order; organ; outcome; output; overall; oxygen; oxygenation; p =; pain; pao2; parameters; partial; participants; pathogen; patients; pco2; pediatric; peep; percentage; performance; perfusion; period; peritonitis; phase; physicians; physiological; picu; piperacillin; placebo; plasma; pleural; pneumonia; points; poisoning; poor; population; position; positioning; positive; possible; post; potential; pph; practice; precarity; predictive; predominance; preliminary; prescription; presence; present; present study; pressure; prevalence; prevention; previous; primary; prior; problem; procedure; process; profile; prognosis; program; prolonged; prone; prophylactic; proportion; prospective; prospective study; protocol; pseudomonas; public; pulmonary; purpose; quality; questionnaire; r =; randomized; range; rate; reasons; recent; records; recovery; reduced; reduction; refractory; refusal; regression; related; relationship; relatives; removal; renal; replacement; report; resistance; respiratory; respiratory failure; responders; response; responsible; results; resuscitation; retrospective; rhythm; right; risk; risk factors; role; room; rrt; safety; samples; saps; satisfaction; scale; score; screening; second; secondary; sedation; seizures; sensitivity; sepsis; september; septic; septic patients; septic shock; series; serum; sessions; setting; severe; severe patients; severity; sex; sham; shock; shock patients; shockable; short; significant; signs; similar; simulation; single; site; skin; sodium; sofa; species; specific; spectrum; spo2; spontaneous; staff; stage; standard; staphylococcus; statistical; status; stay; stec; strains; strategy; stroke; students; studies; study; study patients; study period; success; support; surgery; surgical; survival; survivors; susceptibility; susceptible; syndrome; system; systematic; systolic; table; target; tbi; technique; term; test; testosterone; therapeutic; therapy; tidal; time; tissue; tma; tool; total; tracheal; tracheostomy; training; tramadol; transfusion; transplantation; trauma; traumatic; treatment; trem-1; trend; triage; trial; triggering; ttp; tube; type; ultrasonography; unit; univariate; university; urinary; urine; use; useful; value; vancomycin; vap; variability; variables; variations; vasopressors; venous; ventilation; ventilatory; ventricular; volume; vs.; vulnerable; weaning; weight; withdrawal; women; work; years cache: cord-335975-m6lkrehi.txt plain text: cord-335975-m6lkrehi.txt item: #123 of 134 id: cord-336000-v88bq4bx author: Barco, Stefano title: Enoxaparin for primary thromboprophylaxis in ambulatory patients with coronavirus disease-2019 (the OVID study): a structured summary of a study protocol for a randomized controlled trial date: 2020-09-09 words: 20408 flesch: 38 summary: OVID may increase the level of safety compared to standard of care for study patients because frequent telephone visits are planned (Day 3, 7, 14, 30, 90) . Source data must be available at the site to document the existence of the study participants and substantiate the integrity of study data collected. keywords: ability; activity; acute; additional; administer; administration; adverse; ambulatory; ambulatory patients; analysis; anti; anticoagulant; applicable; assessment; available; baseline; benefit; bleeding; blood; care; case; cec; center; changes; clearance; clinical; clinical study; coagulation; coagulopathy; complications; consent; contact; control; coronavirus; countries; course; cov2; covid-19; covid-19 patients; criteria; current; daily; data; days; death; direct; disease; dose; drug; ecrf; efficacy; end; enoxaparin; enrolment; events; evidence; experimental; factors; following; group; guidelines; health; heart; heparin; higher; home; hospitalization; hospitalized; hot; hours; icu; ill; illness; infection; inflammation; information; informed; initial; injury; instructions; intervention; investigator; key; known; laboratory; line; lmwh; local; major; management; medical; medical patients; medication; months; mortality; myocardial; necessary; non; number; older; outcome; participant; participation; past; patients; person; personnel; phone; physician; place; population; positive; potential; pre; presence; primary; prior; procedures; product; prophylactic; protocol; pulmonary; questionnaire; randomization; randomized; rate; recent; reduced; related; relevant; renal; reporting; requirements; respiratory; results; risk; sae; safety; sample; sars; screening; secondary; setting; severe; signs; single; site; size; sodium; source; specific; sponsor; standard; studies; study; study center; study drug; subject; substantial; surgery; swissmedic; symptoms; syringes; system; test; testing; therapy; thromboembolic; thromboprophylaxis; thrombosis; time; total; treating; treatment; trial; university; use; venous; viral; visit; vte; weight; years cache: cord-336000-v88bq4bx.txt plain text: cord-336000-v88bq4bx.txt item: #124 of 134 id: cord-337129-6wt6wzxv author: Navas de Solis, Cristobal title: Transient diabetes mellitus in a neonatal Thoroughbred foal date: 2010-10-07 words: 3132 flesch: 50 summary: On follow up assessment the foal was found to be a healthy euglycemic animal with normal insulin concentration at 11 months of age. The insulin concentration in normal foals from birth to 7 days of age is 13.5 AE 1.5 mU/mL. 8, 9 keywords: administration; age; cause; concentration; coronavirus; day; days; diabetes; diagnosis; diarrhea; farm; fluid; foal; glucose; healthy; horses; hospitalization; hours; hyperglycemia; injury; insulin; interval; lipase; low; mellitus; mmol; months; neonatal; neonates; normal; pancreatic; plasma; pzi; reference; regular; therapy; thoroughbred; transient; type cache: cord-337129-6wt6wzxv.txt plain text: cord-337129-6wt6wzxv.txt item: #125 of 134 id: cord-337454-0h28a3az author: Chartier, C. title: Prophylaxis using paromomycin of natural cryptosporidial infection in neonatal kids date: 1996-01-31 words: 1704 flesch: 53 summary: Between day 2 and day 10 the mean daily body weight gain of control kids was impaired compared with medicated kids (30 g vs. 80 g) but the difference was not statistically significant. The growth of control kids was inferior to that of medicated kids throughout the study (mean daily body weight gain days 2-10, 100 g vs. 180 g), but the difference was not significant. keywords: age; animals; body; calves; control; cryptosporidial; cryptosporidiosis; daily; days; diarrhea; fayer; france; goat; group; infection; kids; medicated; mortality; oocyst; output; paromomycin; results; second; treatment; weight cache: cord-337454-0h28a3az.txt plain text: cord-337454-0h28a3az.txt item: #126 of 134 id: cord-341063-3rqnu5bu author: None title: 38th International Symposium on Intensive Care and Emergency Medicine: Brussels, Belgium. 20-23 March 2018 date: 2018-03-29 words: 98736 flesch: 48 summary: Since altered liver function has also been described in ICU patients without sepsis [1, 2] , the influence of sepsis may be overestimated. The aim of this work is to analyze the connection between serum and fecal levels of AMM in ICU patients. keywords: 1st; 3rd; 95%ci; aadh; abdominal; abstract; accuracy; accurate; acid; acidosis; acth; activation; activity; acute; addition; adjusted; administration; admission; adult patients; adults; advanced; adverse; affected; age; agents; agitation; agreement; aim; aims; airway; aki; analgesia; analysis; anesthesia; animals; anova; antibiotic; anticoagulation; anxiety; apache; apnea; approach; appropriate; aptt; ards; area; arrest; arrest patients; arterial; artery; assessment; assisted; associated; association; audit; august; available; average; bacteria; balance; baseline; bed; beneficial; benefit; best; better; bilirubin; binding; biomarkers; biopsy; bleeding; blinded; blood; bmi; body; bone; bowel; brain; breathing; burn; bypass; calculated; cancer; candida; candidiasis; cannulation; capillary; cardiac; cardiac arrest; cardiac surgery; cardiopulmonary; cardiovascular; care; care patients; care unit; cases; catheter; cause; cells; center; central; cerebral; challenge; challenging; changes; characteristics; chest; children; chloride; chronic; cirrhosis patients; citrate; clabsi; classification; classified; clearance; clinical; clinician; cmh2o; co2; coagulation; coefficient; cognitive; cohort; cohort study; colistin; collected; colonization; combination; combined; committee; common; communication; comparable; comparison; compliance; complications; compressions; concentrations; conclusions; condition; confidence; consecutive patients; consent; contamination; continuous; contrast; control; control group; conventional; coronary; correlation; cortisol; costs; count; course; cpb; cpr; creatinine; criteria; critical; critical care; critical patients; crp; crrt; culture; current; curve; cvvh; cytokine; daily; damage; data; database; day mortality; days; death; december; decision; decreased; deficit; delirium; delivery; demand; demographic; density; department; detection; deterioration; determined; developed; development; device; dexmedetomidine; diagnosis; diameter; diaphragm; difference; difficult; direct; disability; discharge; disease; disorders; distress; distribution; doctors; donors; doppler; dose; double; driving; drug; dtmax; duration; dvt; dysfunction; dysphagia; early; ecco2r; ecg; ecmo; eeg; effect; effective; efficacy; effort; elderly patients; elective; electronic; elevated; elevation; eligible; eligible patients; elisa; emergency; emptying; ems; end; endothelial; endotracheal; endpoints; energy; environment; episodes; errors; escalation; ethics; evaluation; events; evidence; examination; exclusion; experience; experimental; exposure; expression; extracorporeal; factors; failure; family; fast; feasibility; feeding; female; female patients; femoral; fentanyl; ffp; fig; filter; findings; flow; fluconazole; fluid; fold; following; fraction; free; frequent; functional; future; gas; gastric; gcs; gender; general; general icu; glasgow; global; glucose; glycocalyx; good; greater; group; growth; guidance; guidelines; hbp; head; healthcare; healthy; heart; hemodynamic; hemoglobin; hemorrhage; heparin; hgr; higher; higher mortality; history; hospital; hospital cardiac; hospital discharge; hospital icu; hospital length; hospital mortality; hospital stay; hospitalization; hours; human; hypoglycemia; hypotension; hypothesis; hypoxia; icp; icu admission; icu care; icu day; icu discharge; icu length; icu los; icu mortality; icu patients; icu readmission; icu stay; icu survivors; icu treatment; icus; identification; il-6; il10; ill; illness; imaging; immediate; immune; impact; implantation; implementation; important; improved; improvement; incidence; inclusion; increased; independent; index; india; infection; inferior; inflammation; inflammatory; influence; information; informed; infusion; initial; initiation; injury; intensive; intensive care; intensivists; interval; intervention; intra; intracranial; intraoperative; introduction; intubation; invasive; iqr; ischemic; isolated; items; ivc; january; july; june; key; kidney; knowledge; known; lack; lactate; large; laryngoscope; leading; learning; left; length; levels; levosimendan; life; likely; limited; literature; liver; local; logistic; longer; los; loss; lower; lps; lung; lvad; main; major; majority; making; male; management; map; march; markers; mass; maximum; mdr; mean; mean age; measured; measurements; mechanical; median; medical; medical icu; medication; medicine; members; meta; metabolic; methods; mice; microbiological; microcirculation; microvascular; mild; min; minutes; mixed; mmhg; mmol; model; moderate; modified; monitored; monitoring; months; morbidity; mortality; mortality rate; mortality risk; multicenter; multiple; multivariate; muscle; mv patients; n=1; national; necessary; need; needle; negative; neurological; new; news; non; normal; nosocomial; novel; november; number; nurse; nursing; nutritional; obese patients; objective; observational; observational study; observed; occupancy; occurrence; odds; ohca; old; onset; operating; optimal; oral; order; organ; outcome; output; overall; overt; oxygen; oxygenation; p =; p<0.001; p<0.05; paco2; pain; palliative; palpation; parameters; parenteral; partial; participants; particle; pass; pathway; patients; patterns; pct; pediatric patients; peep; people; percentage; performance; perfusion; period; peripheral; permeability; pfca; pharmacological; phase; phone; physicians; physiological; picu; placebo; plasma; platelet; pneumonia; points; polytrauma patients; poor; population; position; positive; possible; post; postoperative; potential; ppv; practice; predictive; predictors; prehospital; preoperative; prescribed; prescribing; presence; present; present study; pressure; prevalence; prevention; previous; primary; prior; procedure; process; professionals; profile; prognosis; program; prolonged; prophylaxis; proportion; prospective; protein; protocol; psychological; pts; pulmonary; pulse; purpose; quality; questionnaire; questions; radial; randomized; range; rapid; rate; ratios; rats; rbc; rcts; reasons; recent; records; recovery; recruitment; reduced; reduction; reference; referrals; regional; regression; related; relationship; release; relevant; reliability; removal; renal; replacement; reported; requirement; resistance; respiratory; respondents; response; responsiveness; restrictive; results; resuscitation; retrospective; retrospective study; return; review; rhythm; right; risk; risk patients; role; room; rosc; routine; rrt; safety; sah; saline; samples; saps; scale; score; screening; scvo2; search; secondary; sedation; sensitive; sensitivity; sepsis; septic patients; serum; setting; severe; severity; sex; shock; shock patients; short; significant; signs; similar; single; sirs; site; size; skin; sleep; small; sodium; sofa; sofa score; software; species; specific; specificity; spontaneous; stability; staff; stage; standard; start; statistical; status; stay; strategies; strategy; stress; stroke; studies; study; study group; study period; study population; subjects; sublingual; subsequent; success; support; surface; surgery; surgery patients; surgical; surgical icu; surgical patients; survey; survival; survivors; sustained; symptoms; syndrome; system; systemic; systolic; table; tamponade; target; targeted; tbi; tbi patients; team; technique; temperature; term; tertiary; test; therapeutic; therapy; thickness; tidal; time; tissue; tnf; tool; total; tracheotomy; training; transfusion; transplantation; transport; traumatic; traumatic patients; treatment; trend; triage; trial; troponin; tube; txa; type; ultrasound; unclear; underlying; underwent; unit; unit patients; university; university hospital; urine; use; useful; uws; value; vap; variability; variables; variations; vascular; vein; venous; ventilation; ventricular; video; volume; weaning; week; weight; work; worldwide; worse; worsening; years cache: cord-341063-3rqnu5bu.txt plain text: cord-341063-3rqnu5bu.txt item: #127 of 134 id: cord-343349-ftzjdvfj author: Bhatt, P. N. title: Experimental infection of adult axenic rats with Parker's Rat Coronavirus date: 1977 words: 2131 flesch: 47 summary: Parker and eoworkers previously demonstrated that PRCV caused lethal interstitial pneumonia in experimentally infected suckling rats and they suggested that PRCV could play a role in chronic respiratory disease of adult rats (7) . Mouse Hepatitis Virus (MHV), Viruses of Vertebrates Characterization of the Virus of Sialodacryoadenitis of Rats : A Member of the Coronavirus Group Chromatographic purification of tetramethylrhodamine immune globulin conjugates and their use in the cellular localization of rabbit gammaglobulin peptide chains Pathogenesis of Sialodacryoa.denitis in Gnotobiotic Rats Sialodaeryoadenitis in the Rat (A Light and Electron Miserocopic Study) Keratoeonjunctivitis associated with sialodaeryoadenitis in rats Rat Coronavirus (RCV): A Prevalent., Naturally Occurring Pneumotropie Virus of Rats A simple method of estimating fifty percent and endpoints Supported by PHS Grants RR00700, RR00393 and FR 05358. keywords: adult; anti; antibody; antigen; cervical; coronavirus; day; days; epithelium; frozen; glands; infection; interstitial; lacrimal; lesions; lung; lymph; mild; mouse; nasal; necrosis; neutrophils; parker; pneumonia; prcv; rats; respiratory; rhinitis; salivary; sdav; sections; serum; submaxillary; trachea; virus cache: cord-343349-ftzjdvfj.txt plain text: cord-343349-ftzjdvfj.txt item: #128 of 134 id: cord-343789-6tq0kcfd author: Al-Tawfiq, Jaffar A. title: Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study date: 2014-01-06 words: 2633 flesch: 55 summary: Taking stock of the first 133 MERS coronavirus cases globally-is the epidemic changing? Middle East respiratory syndrome coronavirus (MERS-CoV)-update Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia A family cluster of Middle East respiratory syndrome coronavirus infections related to a likely unrecognized asymptomatic or mild case Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive study KSA MERS-CoV Investigation Team. Hospital outbreak of Middle East respiratory syndrome coronavirus Family cluster of Middle East respiratory syndrome coronavirus infections Therapeutic options for Middle East respiratory syndrome coronavirus (MERS-CoV)-possible lessons from a systematic review of SARS-CoV therapy Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reaction Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections Severe acute respiratory syndrome (SARS) in Singapore: clinical features of index patient and initial contacts Severe acute respiratory syndrome: report of treatment and outcome after a major outbreak Investigational use of ribavirin in the treatment of severe acute respiratory syndrome Identification of severe acute respiratory syndrome in Canada A cluster of cases of severe acute respiratory syndrome in Hong Kong Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China Effectiveness of antiviral treatment in human influenza A(H5N1) infections: analysis of a global patient registry Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus Inhibition of novel b coronavirus replication by a combination of interferon-a2b and ribavirin Treatment with interferon-a2b and ribavirin improves outcome in MERS-CoVinfected rhesus macaques Product Information: REBETOL (R) oral capsules solution, ribavirin oral capsules solution The authors (JAT, HM, and JD) wish to acknowledge the use of the Saudi Aramco Medical Services Organization (SAMSO) facilities for the data and study, which resulted in this paper. keywords: a2b; acute; admission; cases; clinical; combination; coronavirus; cov; data; days; disease; dose; east; failure; infections; initiation; interferon; laboratory; mers; middle; oseltamivir; patients; positive; respiratory; ribavirin; severe; syndrome; tables; therapy; time; treatment cache: cord-343789-6tq0kcfd.txt plain text: cord-343789-6tq0kcfd.txt item: #129 of 134 id: cord-346836-6jyv0q5e author: Ikegami, Tetsuro title: The Pathogenesis of Rift Valley Fever date: 2011-05-06 words: 10467 flesch: 44 summary: I. General features of the infection Rift valley fever virus hepatitis: Light and electron microscopic studies in the mouse Pathogenicity of different strains of rift valley fever virus in swiss albino mice The feulgen reaction 75 years on Demonstration of nuclear immunofluorescence in rift valley fever infected cells Identification of a major non-structural protein in the nuclei of rift valley fever virus-infected cells The carboxy-terminal acidic domain of rift valley fever virus nss protein is essential for the formation of filamentous structures but not for the nuclear localization of the protein Rapid accumulation of virulent rift valley fever virus in mice from an attenuated virus carrying a single nucleotide substitution in the m rna The susceptibility of rats to rift valley fever in relation to age Pathogenesis of rift valley fever Inbred rat strains mimic the disparate human response to rift valley fever virus infection Pathogenesis of rift valley fever virus (rvfv) in inbred rats Resistance to rift valley fever virus in rattus norvegicus: Genetic variability within certain 'inbred' strains Active and passive immunization against rift valley fever virus infection in syrian hamsters The gerbil, meriones unguiculatus, a model for rift valley fever viral encephalitis Experimental rift valley fever in rhesus macaques Pathogenesis of rift valley fever in rhesus monkeys: Role of interferon response Prevention of rift valley fever in rhesus monkeys with interferon-alpha The infectivity of rift valley fever for monkeys Vector Borne Zoonotic Dis Replication and dissemination of rift valley fever virus in culex pipiens Vector potential of selected north american mosquito species for rift valley fever virus Vector competence of a houston, texas strain of aedes albopictus for rift valley fever virus Report of a fatal laboratory infection complicated by thrombophlebitis Laboratory infections with the virus of rift valley fever Am Rift valley fever : A report of three cases of laboratory infection and the experimental transmission of the disease to ferrets Human infection with rift valley fever virus and immunity twelve years after single attack Rift valley fever; accidental infections among laboratory workers Rift valley fever; i. keywords: abortion; actinomycin; acute; aerosol; african; age; animals; antibody; antigens; blood; brain; bunyaviridae; c13; cases; cells; challenge; clinical; days; death; dependent; development; different; disease; effects; encephalitis; ewes; experimental; expression; factors; fatal; febrile; fever; fever virus; findings; genetic; gerbils; hamsters; hemorrhagic; hepatitis; hepatocytes; high; host; humans; ifn; illness; immune; immunity; immunization; important; inactivated; infected; infection; inhibition; inoculation; interferon; lambs; lesions; lethal; lewis; like; liver; loss; lymphocytes; major; mechanism; mice; model; mol; monkeys; mortality; mp-12; mrna; necrosis; newborn; normal; nsm; nss; old; onset; outbreak; p.i; pathogenesis; pathological; patients; pfu; phlebovirus; pkr; pregnant; presence; primary; protein; ptv; punta; rats; replication; resistant; responses; rhesus; rift; rift valley; rna; role; rvfv; rvfv infection; s.c; segment; severe; sheep; species; spleen; strain; studies; study; survival; susceptibility; susceptible; symptoms; synthesis; temperature; time; titers; transcription; type; vaccinated; vaccine; valley; valley fever; viral; viremia; virulence; virus; viruses; vision; week; zh501; zh548 cache: cord-346836-6jyv0q5e.txt plain text: cord-346836-6jyv0q5e.txt item: #130 of 134 id: cord-347140-q8qis03p author: Dietz, Thomas title: Earth Day: 50 Years of Continuity and Change in Environmentalism date: 2020-04-17 words: 2464 flesch: 43 summary: From 1969 to 1980, the cornerstones of US environmental policy became law, including the Endangered Species Act, the National Environmental Policy Act, and a dozen laws or amendments to laws to address pollution and toxins in the environment. Environmental concerns sparked the examination of local issues in the context of global processes, leading to an increased emphasis on teleconnections that link ecological and human systems across the planet. keywords: action; analysis; april; century; change; climate; cohort; concern; conservative; day; decision; earth; earth day; environmental; events; future; global; human; issues; making; movement; national; polarization; policy; political; politics; public; republicans; science; scientific; scientists; support; themes; time; values; war; years cache: cord-347140-q8qis03p.txt plain text: cord-347140-q8qis03p.txt item: #131 of 134 id: cord-347716-ka2lm62r author: Usher, Craigan title: Existential Returns date: 2020-06-25 words: 1534 flesch: 61 summary: Groundhog Day tells the story of Pittsburgh meteorologist Phil Connors, who, alongside cameraman Larry, and TV producer Rita travels to Puxatawney, Pennsylvania, to film the annual Groundhog Day celebration. Cynical, disgusted by the kitsch of the event, and the hicks he feels surrounded by, Phil is eager to film his bit and get back to the city. keywords: author; child; coler; colleagues; day; event; existential; february; film; freud; funny; groundhog; joker; ka2lm62r; life; old; patients; people; phil; psychiatry; ready; return; rita; sense; short; story cache: cord-347716-ka2lm62r.txt plain text: cord-347716-ka2lm62r.txt item: #132 of 134 id: cord-349329-f0pbd968 author: Bosteels, Cedric title: Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial date: 2020-06-05 words: 12419 flesch: 40 summary: The study will be conducted cfr the latest version of the ICH E6 (R2) GCP guidelines, creating a standard for the design, conduct, performance, monitoring, auditing, recording, analyses and reporting of clinical studies that provides assurance that the data and reported results are accurate and that the rights, integrity and confidentiality of study subjects are protected. Monitoring services will consist of the following (non-exhaustive list): -review of informed consents and the followed process -check on recruitment status -checking for protocol deviations/violations -checking GCP compatibility -check on safety reporting compliance -IMP handling and storage -review of study data … This study can be inspected at any time by regulatory agencies during or after completion of the study. keywords: -to; active; active group; acute; additional; adverse; alveolar; applicable; ards; area; arterial; assessment; blood; body; care; case; cells; centers; clinical; colony; consent; control; covid-19; covid-19 patients; criteria; csf; ctu; current; daily; data; day; days; disease; dose; drug; early; effects; endpoint; event; factor; failure; ferritin; final; fio2; follow; gas; ghent; group; high; hiruz; hospital; human; hypoxic; icu; immunity; infection; influenza; informed; inhalation; inhaled; intervention; intravenous; invasive; investigator; leukine; local; lung; macrophages; mcg; mechanical; medical; monitoring; mortality; number; option; oxygen; oxygenation; pao2; parameters; patients; period; physician; pneumonia; post; pressure; primary; prior; product; progression; protocol; pulmonary; randomized; rate; redcap; respiratory; respiratory failure; safety; sample; sargramostim; saturation; score; secondary; serum; severe; significant; sponsor; standard; study; subject; support; surface; test; therapy; time; treating; treatment; trial; use; ventilation; ventilatory; viral; visit; ward; weeks cache: cord-349329-f0pbd968.txt plain text: cord-349329-f0pbd968.txt item: #133 of 134 id: cord-350024-whne0l19 author: Anderson, Victoria L. title: Choosing the Right Antibiotic in Ambulatory Care date: 2006-11-28 words: 4737 flesch: 48 summary: Pediatric: neonates, uncircumcised boys, and children with functionally or anatomically abnormal urinary tracts are susceptible to urinary tract infections. Painful scrotal swelling that is often unilateral and can be associated with trauma, urinary tract infection, and STDs. keywords: acute; adult; ambulatory; antibiotics; associated; aureus; available; bacterial; bronchitis; care; causative; cause; cellulitis; children; chronic; clinical; common; criteria; day; days; definition; development; diagnosis; differential; differential diagnosis; disease; erythema; evidence; fever; follow; gram; guidelines; help; history; host; hours; immediate; infection; journal; lice; lyme; management; multiple; nail; negative; nurse; organisms; pain; paronychia; patients; pediatric; pharyngitis; pneumoniae; positive; practice; practitioners; presence; principles; rash; ray; respiratory; skin; superficial; symptoms; systemic; therapy; tick; topical; tract; trauma; treatment; urinary; water; weeks; www.uptodate cache: cord-350024-whne0l19.txt plain text: cord-350024-whne0l19.txt item: #134 of 134 id: cord-355038-o2hr5mox author: None title: Proceedings of Réanimation 2020, the French Intensive Care Society International Congress date: 2020-02-11 words: 102622 flesch: 49 summary: No significant difference between the NE and AVP groups for lactate clearance between H0 and H6 (25.6 [− 7.31 to 35.34]% vs 47.84 [13.42-82.73 ]%, p = 0.686). D: blood frequency of MAIT cells in patients with pneumonia compared with healthy controls (as % of total T cells) keywords: 0.001; abdominal; ability; absence; account; accuracy; accurate; acinetobacter; activity; acute; acute respiratory; addition; adherence; adjusted; adjustment; administration; admission; adult patients; adults; adverse; aeruginosa; age; aged; agents; agreement; aim; airway; aki; aki patients; alive; analysis; anemia; anesthesia; angers; animals; ann; antibiotic; antifungal; antimicrobial; antoine; anxiety; applicable; approach; appropriate; ards; ards patients; area; arf; arrest; arterial; articles; assessment; associated; association; atc; auc; august; available; average; bacterial; bal; balance; baseline; basis; baumannii; bed; benefit; best; beta; better; biological; biomarkers; blood; bmi; body; bolus; brain; breathing; breathing patients; bronchiolitis; bsi; burn patients; calculated; cancer; candida; cannula; caps; cardiac; cardiovascular; care; care patients; care unit; casablanca; cases; catheter; catheterization; cause; cdi; cells; center; central; cerebral; changes; characteristics; chemotherapy; chest; children; chronic; chu; cio; circuit; circulatory; cirrhosis; cirrhotic patients; citrate; classified; clearance; clinical; cmh; cmh2o; cmv; cohort; cohort study; colistin; colonization; coma; combination; common; community; comorbidities; comparison; complete; compliance; complications; component; concentration; conclusion; conditions; confirmed; conflict; congresses; consecutive patients; consequences; consultancy; context; continuous; control; conventional; copd patients; correct; correlation; correspondence; costs; course; cox; cpb; cpr; creatinine; criteria; critical; culture; current; curve; cvc; daily; data; database; day-28; days; death; december; decision; decrease; definition; delay; department; descriptive; detection; development; device; diabetes; diabetic patients; diagnosis; dialysis; diaphragm; diaphragmatic; diastolic; differences; different; difficult; digestive; discharge; disclosure; discomfort; discussion; disease; disorders; distress; dka; dose; dosing; drug; dtf; duration; dysfunction; early; ecco2r; echocardiography; ecmo; ecmo patients; edema; effect; effective; efficacy; efficient; effort; efl; elderly patients; electronic; eligible; embolism; emergency; encephalopathy; end; endotracheal; endpoint; epicuc; epidemiological; epidemiology; epilepticus; episodes; equal; esophageal; ethics regulations; etiology; events; evolution; exacerbation; examination; experienced; experimental; expert; exposure; extracorporeal; extraction; factors; failure; family; fast; fatal; favorable; feasible; features; female; fig; figure; findings; fio2; flow; fluid; following; france; free; french; frequency; frequent; fresenius; functional; fungal; gas; gcs; gender; general; glasgow; global; glove; gnb; gold; good; grade; greater; group; guidelines; guillaume; half; head; health; healthcare; heart; help; hematological; hemodynamic; hemoglobin; hemorrhagic; hepatic; hfd; hfnc; high; high mortality; higher; history; hospital; hospital mortality; hospitalization; hrv; hsv; hypercapnic; hyperoxia; hypnosis; hyponatremia; hypotension; hypothesis; hôpital; icp; icu admission; icu discharge; icu length; icu mortality; icu patients; icu stay; icus; identification; ihd; iii; ill; illness; imipenem; immune; immunocompromised; impact; impairment; implementation; important; improved; improvement; incidence; increase; independent; index; individual; induced; infants; infected; infected patients; infection; inflammation; inflammatory; influenza patients; information; infusion; initial; injuries; injury; insulin; intensive; intensive care; interest; international; intervention; intra; intubated; intubated patients; intubation; invasive; invitation; involved; iqr; ischemic; isolated; isolation; issue; ivc; january; jean; journals; july; june; ketamine; key; kidney; knowledge; known; lack; lactate; large; lead; learning; left; length; lesions; level; life; limited; literature; little; liver; local; logistic; long; longer; lower; lung; main; mait; major; majority; male; malignancies; malignancy; management; marie; martinique; matched; maximal; mcao; mdr; mean; mean age; measurement; measures; mechanical; mechanical ventilation; mechanisms; median; medical; medical care; medical icu; members; membrane; meningitis; mep; methods; mice; microbiological; microorganisms; min; mmhg; mmol; model; moderate; modified; monitoring; monocentric; months; morbidity; mortality; mortality rate; mri; msd; mtx; multicenter; multiple; multivariate; muscle; mwcas; n =; nasal; national; nava; nebulization; need; negative; neurological; neuromuscular; neutropenia; neutropenic patients; new; nicolas; niv; non; normal; nosocomial; nssh patients; number; nurses; nutrition; objective; observational; observational study; observed; occurrence; odds; old; onset; operating; operative; optimal; organ; outcome; overall; oxygen; oxygenation; p =; pain; pancreatitis; parameters; parents; paris; participants; particular; pathogens; pathways; patients; pcr; pct; peak; pediatric; peep; percent; performance; period; peritonitis; persistent; pes; pfizer; phase; physicians; physiological; picu; piperacillin; placebo; plasma; platelet; pmus; pneumonia; points; poisoning; poor; population; position; positive; positive patients; possible; post; potential; ppv; practices; predictive; predictors; predominance; prehospital; prescription; presence; present; presentation; pressure; prevalence; prevention; previous; primary; prior; problem; procedure; process; profile; prognosis; program; prolonged; prone; prophylaxis; proportion; prospective; protein; protocol; pseudomonas; psv; psychological; psychologist; pulmonary; purpose; purulent; quality; randomized; range; rapid; rare; rate; ratio =; rationale; rbc; reactivation; reasons; recent; recommendations; recovery; reduction; refractory; regional; regression; related; relationship; relatives; reliable; remains; renal; replacement; report; research; resistance; respiratory; respiratory failure; response; responsible; responsiveness; results; resuscitation; retrospective; retrospective study; review; right; risk; risk factors; role; room; rri; rrt; rsv patients; réanimation; safety; samples; saps; sbt; scale; scan; scientific; score; secondary; sedation; seizures; sensitivity; sepsis; september; septic; septic patients; serum; service; sessions; setting; severe; severe acute; severe patients; severity; sex; shock; shock patients; short; significant; signs; similar; simplified; single; sirs; site; situations; size; small; sofa; software; specialized; species; specific; specificity; spectrum; spontaneous; staff; stage; standard; standardized; statistical; status; stay; step; strains; strategies; strategy; stroke; stroke patients; strong; studies; study; study day; study group; study period; subjects; success; successful; suppl; support; surgery; surgical; survey; survival; survivors; susceptibility; symptoms; syndrome; system; systematic; systolic; table; tapse; target; tbi; teaching; team; techniques; term; test; testing; therapeutic; therapy; thoracic; threatening; threshold; thrombocytopenia; thrombolysis; tidal; time; tools; total; total patients; toxicity; tracheostomy; training; transfusion; transient; transition; transplantation; trauma patients; traumatic; treatment; trial; tube; tumor; tunisia; type; ultrasound; underlying; underwent; unit; unit patients; univariate; university; use; useful; vaccination; validated; value; vancomycin; vap; vap patients; variables; variation; vein; venous; ventilation; ventilatory; ventricular; viral; virus; visual; volume; weakness; weaning; weight; women; work; workers; worldwide; years cache: cord-355038-o2hr5mox.txt plain text: cord-355038-o2hr5mox.txt