Bibliography
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- cord-013477-dzm4xi21
- author: Filardi, Tiziana
- title: Curcumin: Could This Compound Be Useful in Pregnancy and Pregnancy-Related Complications?
- date: 2020-10-17
- words: 7278
- flesch: 30
- summary: Systems biology and the recently developed network pharmacology represent new strategies to better comprehend the mechanisms underlying curcumin activities in the human body. The pleiotropic and multi-targeting actions of curcumin have made it very attractive as a health-promoting compound.
- keywords: able; activation; activities; activity; administration; alcohol; alterations; analysis; antidepressant; antioxidant; apoptosis; authors; benefits; birth; body; brain; cells; complications; compound; curcumin; damage; data; day; development; diabetes; diabetic; dietary; different; diseases; disorders; effects; epigenetic; exposure; expression; factors; fetal; fgr; gdm; genes; gestational; glucose; growth; health; human; il-6; immune; implantation; improved; induced; inflammation; inflammatory; insulin; levels; lipid; liver; low; lps; major; maternal; mechanisms; mellitus; metabolic; mice; model; molecular; mouse; mrna; natural; neurogenesis; neuroprotective; offspring; outcomes; oxidative; pathways; patients; placental; possible; potential; preeclampsia; pregnancy; pregnant; proliferation; protein; pups; randomized; rats; recent; reduced; reduction; related; results; review; role; serum; signaling; significant; stress; studies; study; supplementation; symptoms; treatment; trial; trophoblast; vitro; weeks; weight; women
- versions: original; plain text
- cord-023157-0lqlx2rv
- author: None
- title: Poster Sessions
- date: 2013-04-18
- words: 128609
- flesch: 50
- summary: Results: Mean values of WC, blood pressure (BP), fasting plasma glucose (FPG), triglycerides (TG), HDL-Cholesterol and BMI were significantly higher in men than in women who had higher %BF (28% vs. 21%). Results: During IvGTT GBP-pigs displayed lower glucose and higher insulin levels compared to controls.
- keywords: 0.001; 1st; 2nd; 3rd; 95%ci; = ns; abdominal; abdominal obesity; abnormalities; absence; accumulation; acid; acr; action; activation; activities; activity; acute; addition; adipocytes; adipokines; adiponectin; adiponectin levels; adipose; adiposity; adjusted; adjustment; adma; administration; adolescents; adults; adverse; ae sd; affected; age; age group; aged; agents; aim; aims; akt; albumin; alcoholic; allele; alpha; alterations; altered; analysis; analyzed; angiography; angiotensin; animals; anthropometric; anti; antioxidant; apo; applied; approach; appropriate; area; arterial; artery; assay; assessment; associated; association; atherogenic; atherosclerosis; atp; available; average; b =; background; balance; bariatric; basal; baseline; behavior; beneficial; benefits; best; beta; better; bioactive; biochemical; biological; biomarkers; birth; blood; blood glucose; blood pressure; blot; bmi; bnp; body; body fat; body mass; body weight; bone; boys; brain; brazil; breakfast; burden; bypass; c levels; cad; cad patients; cafeteria; calculated; calorie; cancer; candesartan; capacity; carbohydrate; cardiac; cardiometabolic; cardiovascular; cardiovascular disease; cardiovascular patients; cardiovascular risk; care; carotid; carriers; cases; cataract; cause; cells; center; central; chain; changes; characteristics; characterized; chemerin; children; cholesterol; cholesterol levels; chronic; circulating; circumference; ckd; classified; clinical; coefficient; cohort; cohort study; collected; combination; combined; common; community; comparable; compare; comparison; complex; complications; components; composition; concentrations; conclusion; conditions; confidence; consecutive; consumption; content; control; control group; control study; control subjects; coronary; correlated; correlation; corresponding; countries; creatinine; crf; crime; criteria; cross; crp; current; curve; cutoff; cvd; cytokines; daily; damage; data; day; days; dbp; death; decreased; decreasing; deficiency; definition; degree; demographic; density; department; design; detection; determined; development; diabetes; diabetes group; diabetes mellitus; diabetes risk; diabetes type; diabetes women; diabetic patients; diabetic subjects; diabetics; diagnosis; diastolic; diastolic blood; diet; dietary; differences; different; differentiation; direct; disease; disorders; distribution; dm patients; dm2; dose; drug; duration; dysfunction; dyslipidemia; early; eating; education; effect; effective; effectiveness; efficacy; elderly; elderly patients; elevated; elisa; endocrine; endothelial; endotoxin; energy; enzymes; epidemic; established; estimated; evaluation; evening; events; evidence; examination; excess; excessive; exenatide; exercise; expenditure; experimental; expression; factors; faculty; failure; families; family; fasting; fat; fat diet; fat mass; fatty; fbg; fbs; features; fed; females; ferritin; fetal; ffa; fiber; fibrosis; findings; flow; fmd; fold; follow; following; food; foot; fpg; fraction; free; frequency; frequent; function; future; gain; gastric; gbp; gdm; gender; gene; general; genetic; genotype; gestational; gestational diabetes; ggt; ghrelin; gip; girls; glp-1; glucagon; glucose; glucose concentration; glucose homeostasis; glucose levels; glucose metabolism; glucose study; glucose tolerance; glutathione; glycaemia; glycation; glycemic; good; gpx; greater; group; group patients; growth; guidelines; gut; habits; half; hand; hba1c; hdl; health; healthy subjects; heart; help; hemoglobin; hepatic; hepatocytes; hfd; high blood; high fat; high glucose; high insulin; high levels; high prevalence; higher; higher bmi; higher body; higher risk; highest; histological; history; hla; homa; homeostasis; homocysteine; hormone; hospital; hour; hr =; hscrp; human; hyperglycemia; hyperinsulinemia; hypertension; hypertensive patients; hypertriglyceridemia; hyperuricemia; hypoglycemic; hypoxia; idf; ifg; igt; ihd; iii; il-18; il-6; impact; impaired; impaired glucose; impairment; important; improved; improvement; imt; incidence; increased; incretin; independent; index; indexes; india; indicators; indices; individuals; induced; infarction; inflammation; inflammatory; influence; information; infusion; ingestion; inhibited; inhibitor; injury; institute; insulin; insulin levels; insulin resistance; insulin secretion; insulin sensitivity; intake; interest; international; interval; intervention; intervention group; intracellular; introduction; inverse; involved; iran; iron; irs-1; ischemic; islets; isolated; kcal; key; kidney; kit; knowledge; known; laboratory; lack; large; later; ldl; leading; lean; left; leptin; leptin levels; levels; lifestyle; like; likely; limited; linear; lipid; lipoprotein; liposuction; liraglutide; liver; lmol; logistic; long; loss; low; lower; lower levels; lowest; lps; lunch; macrophage; macrosomia; magnesium; main; major; male patients; management; mann; marked; markers; mass; mass index; material; maximal; maximum; meal; mean; mean ae; measured; measurements; mechanisms; median; medical; medicine; membrane; metabolic; metabolic control; metabolic parameters; metabolic risk; metabolic syndrome; metabolites; metformin; methods; mets; mets patients; mice; microalbuminuria; mild; mitochondrial; mixed; mmhg; mmol; mmp-9; model; moderate; modification; modified; molecular; monitoring; months; morbidity; morning; mortality; mrna; msg; multiple; multivariate; munc18c; muscle; myocardial; myriocin; n =; n-3; nafld; nampt; nash; national; ncep; necessary; need; negative; neuropathy; new; ngt; nitric; nmol; non; nondiabetic; normal; normal glucose; normal weight; novel; npdr; number; nutrition; obese; obese group; obese patients; obese subjects; obese women; obesity; obesity group; objective; observed; odds; offspring; ogtt; oil; old; older; onset; opg; oral; osteocalcin; outcomes; overall; overt; overweight; oxidation; oxidative; oxide; oxldl; oxygen; p =; p peak; pain; pancreas; pancreatic; parameters; participants; pathogenesis; pathway; patients; pattern; pcos; pcos patients; pcr; peak; people; peptide; percentage; period; peripheral; persons; phenotype; phosphorylation; physical; physical activity; physiological; physiology; placebo; plant; plasma; plasma glucose; plasma insulin; plasma leptin; plasma levels; pmol; point; polymorphism; pon1; poor; population; positive; possible; post; postmenopausal; postprandial; potential; pparc; practice; preadipocytes; prediabetes; predictive; predictor; pregnancies; pregnancy; pregnant; presence; present; present study; pressure; prevalence; prevention; previous; primary; prior; probiotic; problem; process; products; profile; program; project; promoter; properties; proportion; prospective; prospective study; protein; psychological; pts; public; pulse; purpose; pwv; qol; quality; quantitative; questionnaire; r =; randomized; range; rate; ratio; rats; reactive; recent; receptor; recommendations; reduced; reduction; reference; region; regional; regression; regular; regulation; rehabilitation; relationship; relative; release; renal; report; research; resistant; resistin; response; restriction; results; retinopathy; retrospective; risk; risk factors; risk group; risk patients; rmr; role; routine; rygb; salivary; sample; sat; sbp; scale; school; sciences; score; screening; secondary; secretion; sectional; sectional study; sedentary; self; sensitive; sensitivity; serum; serum glucose; serum insulin; serum leptin; serum levels; severe; severity; sex; short; shr; signaling; significant; significant correlation; significant differences; significant higher; significant increase; significant reduction; significant risk; similar; single; size; skeletal; small; smokers; smoking; snp; social; socioeconomic; sod; south; specific; specificity; spss; standard; standardized; state; statin; statistical; status; steatohepatitis; steatosis; stiffness; stimulated; strength; stress; stroke; strong; students; studies; study; study group; study population; subcutaneous; subjects; subsequent; sugar; superior; supplementation; support; surgery; survey; symptoms; syndrome patients; system; systolic; t2 dm; t2d; t2d patients; target; tcf7l2; terms; test; tested; testing; testosterone; therapeutic; therapy; thickness; thyroid; time; tissue; tnf; tolerant; total; total cholesterol; traditional; training; transcription; treatment; trend; trial; triglycerides; type; ultrasound; unclear; underlying; underwent; university; urban; uric; use; useful; values; variables; variant; vaspin; velocity; ventricular; vildagliptin; visceral; vitamin; vivo; volunteers; vs.; waist; waist circumference; wave; weeks; weight; weight gain; weight loss; weight patients; western; whitney; whr; whtr; wistar; women; workers; world; worldwide; years; years old; yoga; young
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- cord-026990-d3l1sbeb
- author: Oberoi, Sumit
- title: Economic menace of diabetes in India: a systematic review
- date: 2020-06-17
- words: 4992
- flesch: 54
- summary: A large proportion of health care cost is confronted by the patients themselves, which affects the fulfilment of health care because of financial restraints [62] . The economic burden of diabetes in India: results from a national survey Cost of medical care among type 2 diabetic patients with a co-morbid conditionhypertension in India Direct costs associated with chronic kidney disease among type 2 diabetic patients in India Factors influencing medical tourism in India: a critical review Costs of diabetes The economic burden of depression in Sweden from Economic costs of diabetes in the US in 2002 A prospective study of outcomes, healthcare resource utilization, and costs associated with postoperative nosocomial infections The prevalence of multi-morbidity in primary care and its effect on health care utilization and cost The burden of epilepsy for the patient: the intangible costs Economics of psychosocial factors in patients with cardiovascular disease The economic burden of diabetes in India: a review of the literature Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations
- keywords: ---the; analysis; annual; annum; articles; burden; care; comorbidities; complications; cost; costing; country; data; diabetes; diabetic; direct; direct cost; disease; drugs; east; economic; expenditure; factors; health; hospitalisation; household; illness; india; indirect; individual; items; level; literature; loss; majority; mean; median; medicines; mellitus; north; p.a; patients; present; quality; review; sample; size; south; studies; study; systematic; table; total; treatment; type; viz; west; zone
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- cord-027036-lvcxrmih
- author: Shaw, Ken
- title: The impact of diabetes on COVID‐19 infection
- date: 2020-06-09
- words: 2057
- flesch: 32
- summary: 2 Such disturbances of immune function are very likely to have significant impact on the outcome of COVID-19 infection complicated by diabetes. These early reports of COVID-19 infection included observations of 52 critically ill adult patients with coronavirus pneumonia admitted to the ICU at the Wuhan Jin Yin-tan hospital, where diabetes was found in twice the number of individuals who died compared to those who survived (22% vs 10%).
- keywords: adverse; care; cases; china; clinical; control; coronavirus; covid-19; data; diabetes; disease; early; england; epidemic; experience; hospital; immune; individuals; infection; inflammatory; influenza; likely; management; national; nhs; outcome; pandemic; patients; people; pneumonia; proportion; response; risk; sars; severe; wuhan
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- cord-028967-l5ioyhur
- author: Scherbaum, Werner A.
- title: Diabetes Update 2020: das Wichtigste für die ärztliche Praxis
- date: 2020-07-10
- words: 2097
- flesch: 38
- summary: In der mit TWO2 behandelten Gruppe waren 12 Monate nach Beginn der Studie 56 % der Ulzera abgeheilt, in der Kontrollgruppe 27 % ( [26] , . Das zeigte auch eine kürzlich publizierte dänische Studie, bei der Personen mit Typ-2-Diabetes über 6
- keywords: abb; aber; als; amputationen; anti; auch; auf; aus; bei; cardiovascular; closed; covid-19; dass; dem; den; der; des; deutschland; diabetes; diabetesremission; diabetic; diabetischen; diabetologe; die; dpv; durch; einer; ergebnisse; für; hba1c; hinweg; hypertension; important; innen; interventionsgruppe; jahr; kontrollgruppe; loop; mahlzeiten; majoramputationen; mit; monaten; nach; nachgewiesen; nicht; nur; patienten; patients; pro; publizierten; reduktion; retinopathy; risk; sich; signifikant; studie; system; t1d; tag; teilnehmer; therapie; therapy; topics; trial; two2; typ-2; type; und; unter; unteren; vegf; vergleich; von; vorteil; war; waren; wurde; zur; über
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- cord-030631-cc79j9j4
- author: Marcus, Benjamin A.
- title: Typ-1-Diabetes: Früherkennung und Ansätze zur Prävention: Update 2020
- date: 2020-08-19
- words: 2249
- flesch: 38
- summary: Die Ergebnisse dieser Untersuchung, die für mehr als die Hälfte der Behandelten eine Verdoppelung der Zeit bis Auch wenn derzeit noch nur davon ausgegangen werden sollte, dass sich für die behandelten Patienten der Beginn der Erkrankung weiter in die Zukunft verschiebt und der Effekt bei einer dauerhaft therapiebedürftigen Erkrankung moderat erscheinen mag, wirkt sich gerade bei Kindern jedes gewonnene klinisch gesunde Jahr noch weit mehr aus als im Erwachsenenalter.
- keywords: als; antibody; auch; auf; autoimmune; autoimmunity; bavaria; behandlung; bei; bereits; betazellen; children; clinical; das; dass; dem; der; des; diabetes; diagnosis; die; dieser; durch; early; eine; entstehen; erkrankung; fr1da; früherkennung; für; gegen; genetic; germany; gestörte; glukosetoleranz; high; incidence; infants; insulin; islet; ist; jahre; journal; kann; manifestation; mehr; mit; nach; nachweis; nicht; noch; nur; oder; onset; oral; point; possible; prevention; primary; progression; präventive; risk; screening; sich; stadium; stage; studie; study; teplizumab; treatment; trial; typ-1; type; und; update; von; vor; werden; wie; wird; years; young; zur; über
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- cord-214006-0w6bqrox
- author: Aghdam, Atae Rezaei
- title: Towards Empowering Diabetic Patients: A perspective on self-management in the context of a group-based education program
- date: 2020-10-26
- words: 4824
- flesch: 39
- summary: This is essentially a reality for people with chronic disease such as diabetes patients who need informational and emotional supports that allow them to be successful in their disease self-management (Litchman and Edelman 2019) . As such, this study aims to investigate the potential practices of online diabetes communities to address the following question; how can an online diabetes community empower patients in context of a Diabetes Group Education Program (DGEP)?
- keywords: 2020; access; activities; advice; aghdam; analysis; better; chronic; communities; community; context; creation; data; dgep; diabetes; diabetic; disease; education; emotional; empowerment; et al; experience; face; findings; framework; group; health; healthcare; information; interactions; life; management; members; ohcs; online; opportunities; outcomes; patients; peers; people; platforms; potential; program; quality; reddit; research; self; service; sharing; social; solutions; stories; study; support; themes; theory; topics; type-2; users; value
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- cord-254494-wbfgrez1
- author: Shi, Chunhong
- title: Barriers to Self-Management of Type 2 Diabetes During COVID-19 Medical Isolation: A Qualitative Study
- date: 2020-10-14
- words: 5755
- flesch: 39
- summary: The purpose of this study was to explore perceived barriers among type 2 diabetes patients during isolation following their recovery from COVID-19. Perceived barriers to diabetes self-management described by diabetes patients indicated a lack of environmental resources and support strategies to meet their needs.
- keywords: adherence; barriers; behaviors; beliefs; blood; care; china; chinese; community; control; coronavirus; covid-19; data; diabetes; diabetes self; diet; discharged; disease; education; emotions; facilities; family; female; findings; glucose; glycemic; health; healthcare; hospital; hypoglycemic; inadequate; information; interviews; isolation; knowledge; lack; levels; limited; low; management; medical; medications; mellitus; members; monitoring; negative; outcomes; participants; patients; physical; prevention; problems; providers; qualitative; quality; research; resources; self; selfmanagement; shortage; sites; social; studies; study; suffering; support; themes; treatment; type
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- cord-255687-jud875xc
- author: García-Villasante, Eilhart
- title: Diabetes care during COVID 19: Experience in telemedicine from a developing country
- date: 2020-08-04
- words: 577
- flesch: 49
- summary: Pitfalls in telemedicine consultations in the era of covid 19 and how to avoid them Reported Cases and Deaths by Country, Territory, or Conveyance Risk factors for mortality in patients with coronavirus disease 2019 (covid-19) infection: a systematic review and meta-analysis of observational studies. Our main concern is about diabetic patients because they are at major risk to get infected and develop severe forms of disease (3).
- keywords: article; authors; care; country; covid; diabetes; health; j.dsx.2020.07.046; journal; medications; patients; telemedicine; version
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- cord-260119-pgu2crhs
- author: Golledge, Jonathan
- title: The Potential Role of Sensors, Wearables and Telehealth in the Remote Management of Diabetes-Related Foot Disease
- date: 2020-08-13
- words: 6774
- flesch: 38
- summary: Given the established effect of leg ischemia on foot temperature and the exclusion of participants with this problem from prior trials [17] [18] [19] [20] 24] , the role of home foot temperature monitoring in people with PAD remains unclear. Recently, a further clinical trial reported on the efficacy of foot temperature monitoring performed at only monthly intervals at an out-patient clinic, rather than at home [24] .
- keywords: activity; adherence; analysis; artery; assessment; available; better; blood; care; clinical; consultations; continuous; control; data; developed; development; devices; dfd; diabetes; diabetic; diabetic foot; disease; dpn; evidence; feet; foot; foot temperature; foot ulcers; footwear; gait; glucose; group; high; history; home; incidence; infrared; insoles; intervention; management; medical; meta; methods; mobile; monitoring; mortality; need; offloading; outpatient; pad; participants; patients; people; peripheral; phone; plantar; pressure; prevention; previous; prior; randomized; recent; recurrence; remote; research; review; risk; role; sensors; sites; small; smart; study; system; systematic; technology; telehealth; telemedicine; temperature; time; trial; type; ulceration; ulcers; use; value; wearables
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- cord-260713-wxfc1aaz
- author: Kyle Jacques, Rose
- title: The COVID19 Pandemic – Perspectives from People Living with Diabetes
- date: 2020-07-22
- words: 1024
- flesch: 59
- summary: Add a global pandemic to the already monumental expectations placed on us to live healthily and maintain glucose levels in range, and it's not surprising that many people with diabetes are finding these trying times especially difficult. During the pandemic, many people with diabetes have felt more anxious, even scared, about situations out of their control.
- keywords: authors; care; covid-19; covid19; day; diabetes; difficult; glucose; impact; important; levels; management; pandemic; people; social; support; time
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- cord-263908-4ti8l2ea
- author: Gupta, Ritesh
- title: Diabetes and COVID-19: evidence, current status and unanswered research questions
- date: 2020-05-13
- words: 3695
- flesch: 41
- summary: Prevalence ofcomorbidities in the novel Wuhan coronavirus (COVID-19) infection: asystematicreview and meta-analysis Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China Effects of hypertension, diabetes and coronary heart disease on COVID-19 diseases severity: a systematic review and meta-analysis Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention Glycemic characteristics and clinical outcomes of COVID-19 patients hospitalized in the United States Glycemic control and risk of infections among people with type 1 or type 2 diabetes in a large primary care cohort study Type 2 diabetes mellitus and altered immune system leading to Diabetes and COVID-19: evidence, current status and unanswered research questions susceptibility to pathogens, especially mycobacterium tuberculosis T-cell activation and cardiovascular risk in adults with type 2 diabetes mellitus: A systematic review and meta-analysis Covid-19 and diabetes mellitus: unveiling the interaction of two pandemics Obesity and the risk and outcome of infection Elevated Plasmin(ogen) as a common risk factor for COVID-19 susceptibility Diabetes is a risk factor for the progression and prognosis of COVID-19 Plasma levels of the proprotein convertase furinandincidence of diabetes and mortality There have been a lot of literature and debate whether these drugs could benefit or harm patients having COVID-19 infection.
- keywords: ace2; acute; analysis; angiotensin; anti; arbs; blockers; blood; cell; china; clinical; converting; coronavirus; course; covid-19; diabetes; disease; dpp4; drugs; effect; entry; enzyme; evidence; factors; glucose; high; hypertension; increase; india; infection; inhibitors; injury; insulin; issues; levels; like; lockdown; lung; meta; mortality; need; patients; people; prevalence; receptor; respiratory; response; risk; sars; severe; severity; study; syndrome; treatment; type; use; viral
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- cord-264295-7ojvhwb0
- author: Maddaloni, Ernesto
- title: Cardiometabolic multimorbidity is associated with a worse Covid-19 prognosis than individual cardiometabolic risk factors: a multicentre retrospective study (CoViDiab II)
- date: 2020-10-01
- words: 4691
- flesch: 34
- summary: Age and sex adjusted regression models confirmed that Covid-19 patients with the primary composite outcome were more likely to have diabetes (adjusted odds ratio [ adj OR] 2.04, 95% confidence interval Overall our results confirm previous findings from other countries that Covid-19 patients with diabetes are more likely to require intensive care or to die, compared with Covid-19 patients without diabetes [12, 19, 20, 27] , and in addition suggest this association is driven by the presence of cardiometabolic multimorbidity rather than by diabetes alone.
- keywords: 95%ci; additional; adj; admission; age; association; available; blood; bmi; cardiometabolic; cardiometabolic multimorbidity; cardiometabolic risk; cardiovascular; care; characteristics; clinical; composite; composite outcome; conditions; copd; covid-19; data; death; design; diabetes; differences; disease; dyslipidaemia; factors; failure; features; glucose; heart; higher; hospital; hypertension; icu; impact; independent; infection; multimorbidity; outcome; p =; patients; primary; primary composite; progression; ratio; risk; risk factors; sars; secondary; sex; single; study; system; table; type
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- cord-266702-6oxtlzqo
- author: Cristelo, Cecília
- title: SARS-CoV-2 and Diabetes: New Challenges for the Disease
- date: 2020-05-22
- words: 4064
- flesch: 38
- summary: Taking advantage of ACE2, SARS-CoV-2 gains access to the cells, however it has been shown that soon after infection ACE2 expression is rapidly downregulated [8] . Whether this effect is caused by the virus, to prevent ACE2 protective effects [28] , or results from an indirect mechanism is not yet clear.
- keywords: ace2; aceis; activity; angiotensin; anti; arbs; associated; blockers; cause; cells; china; clinical; complications; control; converting; coronavirus; covid-19; damage; diabetes; disease; effects; enzyme; evidence; expression; function; glucose; higher; human; hyperglycemia; hypertension; infection; inhibitors; injury; insulin; kidney; levels; lung; mellitus; mortality; ncov; novel; pancreas; patients; pneumonia; progression; protective; protein; receptor; renin; respiratory; risk; role; sars; severe; spike; studies; study; system; treatment; type; use; wuhan
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- cord-269856-6h3j89wn
- author: Paolo Fadini, Gian
- title: Newly-diagnosed diabetes and admission hyperglycemia predict COVID-19 severity by aggravating respiratory deterioration
- date: 2020-08-15
- words: 3942
- flesch: 37
- summary: We evaluated which of these parameters explained the association between glucose levels and COVID-19 severity outcome (i.e. being mediators). We then evaluated whether these correlations could partially explain (i.e. mediate) the association between FPG and COVID-19 severity outcome.
- keywords: admission; age; analysis; association; c.i; cardiovascular; characteristics; clinical; control; covid-19; damage; data; days; diabetes; diabetic; disease; effect; existing; figure; fpg; glucose; hba1c; higher; hospitalization; hyperglycemia; icu; laboratory; levels; lung; medical; mmol; models; mortality; organ; outcome; p<0.001; patients; poor; pre; primary; respiratory; risk; sars; severe; severity; sex; significant; stronger; study; subjects; symptoms; table; time; variables; worst
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- cord-274548-yeucn13x
- author: Altobelli, Emma
- title: Lifestyle Risk Factors for Type 2 Diabetes Mellitus and National Diabetes Care Systems in European Countries
- date: 2020-09-13
- words: 3819
- flesch: 50
- summary: The aim of this work is to highlight within EU-28 countries the distribution percentages of some lifestyle risk factors and some components of diabetes health care. For diabetes mellitus, this means a combination of programs The first quadrant includes the following countries and variables-Finland, the United Kingdom, Ireland, Sweden, Belgium, Austria, Luxembourg, the Netherlands, each showing a mortality rate below 25.0, diabetes <6%, stable mortality trend, and with diabetes care entrusted to general practitioners.
- keywords: analysis; bulgaria; care; chronic; control; countries; country; czech; data; diabetes; estonia; eu-28; european; expenditure; factors; france; general; health; hungary; inactivity; italy; latvia; malta; mellitus; mortality; national; national diabetes; ndp; obesity; overweight; percentage; physical; plan; presence; prevalence; prevention; rate; registries; republic; results; risk; spain; systems; total; trend; type; values
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- cord-276256-gmlsoo2z
- author: Avilés-Santa, M. Larissa
- title: Current State of Diabetes Mellitus Prevalence, Awareness, Treatment, and Control in Latin America: Challenges and Innovative Solutions to Improve Health Outcomes Across the Continent
- date: 2020-10-10
- words: 9707
- flesch: 30
- summary: Integrating social determinants of health into diabetes care demonstrated objective improvements in patient knowledge and cardiometabolic parameters [233] . Many interventions on diabetes care have focused on patients and/or clinicians as the primary recipients or enablers of the interventions.
- keywords: access; ada; adherence; adults; america; analysis; assessment; associated; association; attainment; awareness; blood; brazil; cardiovascular; care; challenges; chronic; clinical; communities; community; completion; complications; comprehensive; control; countries; current; detection; diabetes; diabetes care; diabetes mellitus; diabetes prevalence; diabetic; disease; education; factors; fasting; foot; global; glucose; glycemic; goals; groups; guatemala; guidelines; hba1c; health; health care; high; higher; hyperglycemia; hypertension; impact; implementation; income; indigenous; individuals; insurance; interventions; kidney; latam; latin; latin america; ldl; levels; low; lower; management; medical; medications; mellitus; mexican; mexico; microvascular; middle; model; mortality; multiple; national; need; non; number; nutrition; obesity; older; outcomes; patients; people; persons; peru; population; practice; pressure; prevalence; prevention; primary; program; public; puerto; quality; range; region; reports; research; results; retinopathy; review; rico; risk; risk factors; rural; screening; self; services; settings; specific; status; studies; study; support; surveys; system; systematic; table; test; time; transition; treatment; type; undiagnosed; urban; uruguay; women; years
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- cord-284245-y8q0cjbk
- author: Vallis, Michael
- title: Mental Health in Diabetes: Never a Better Time
- date: 2020-08-10
- words: 1052
- flesch: 42
- summary: Yared et al (1) present a paper describing how a multidisciplinary type 1 clinic has incorporated the assessment and management of diabetes distress into their practice. Morrissey et al (5) present a paper on the role of diabetes distress in adolescents and young adults living with type 1 diabetes.
- keywords: adults; care; depression; diabetes; distress; education; health; impact; issue; management; mental; pandemic; patients; review; self; time; type
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- cord-287362-dhl7ynrc
- author: Unnikrishnan, Ranjit
- title: Infections and diabetes: Risks and mitigation with reference to India
- date: 2020-09-22
- words: 3990
- flesch: 30
- summary: The role of diabetes mellitus in patients with bloodstream infections Immune dysfunction in patients with diabetes mellitus (DM) Type 2 diabeets and its impact on the immune system Pattern of infections in patients with diabetes mellitus--Data from a tertiary care medical center in Indian Subcontinent Increased risk of common infections in patients with type 1 and type 2 diabetes mellitus Diabetes and tuberculosis: an important relationship Coprevalence of type 2 diabetes mellitus and tuberculosis in low-income and middleincome countries: A systematic review Diabetes and tuberculosis: an appraisal Clinical profile of urinary tract infections in diabetics and non-diabetics Clinical practice guideline for the management of asymptomatic bacteriuria: 2019 update by the Infectious Diseases Society of America Genital infections with sodium glucose cotransporter-2 inhibitors: occurrence and management in patients with type 2 diabetes mellitus Case of acute unilateral emphysematous pyelonephritis and bacteraemia on treatment with canagliflozin Epidemiology of diabetic foot infections in a reference tertiary hospital in India Bacterial etiology of diabetic foot infections in South India Microbiological and clinical characteristics of diabetic foot infections in northern India Infections and diabetes Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China Prevalence and impact of diabetes among people infected with SARS-CoV-2 COVID-19 in people with diabetes: understanding the reasons for worse outcomes COVID19 in South Asians/Asian Indians: Heterogeneity of data and implications for pathophysiology and research COVID-19 in people living with diabetes: An international consensus Clinical characteristics and risk factors for mortality of COVID-19 patients with diabetes in Wuhan, China: A two-Center, retrospective study New-onset diabetes in COVID-19 National Diabetes Obesity and Cholesterol Foundation (NDOC), and Diabetes Expert Group, India. In this context, it should also be noted that the nationwide lockdowns imposed in India and other countries to combat the spread of the COVID-19 pandemic have had an adverse impact on the coverage of infection control and immunization programs directed against other communicable disease; these countries should gear up to face a recrudescence of many of these hitherto controlled infections in the near future (60) .
- keywords: associated; blood; care; characteristics; china; clinical; common; control; countries; cov2; covid-19; diabetes; diabetic; diet; disease; effects; foot; glucose; glycemic; healing; higher; hyperglycemia; impact; india; individuals; infections; levels; likely; long; management; mellitus; mortality; new; organisms; outcomes; pandemic; patients; people; poor; population; respiratory; review; risk; sars; severe; studies; study; supplementation; tight; tissue; tract; treatment; tuberculosis; type; uncontrolled; worse
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- cord-292344-3bj567gr
- author: Zimmet, P.
- title: The burden of type 2 diabetes: are we doing enough?
- date: 2003-09-30
- words: 5322
- flesch: 45
- summary: Diabetes Care The changing demography of diabetes mellitus in Singapore Epidemiologic study of type 2 diabetes in Taiwan WHO Ad Hoc Diabetes Reporting Group: global estimates for prevalence of diabetes mellitus and impaired glucose tolerance in adults Diabetes trends in Latin America Diabetes trends in Africa Diabetes trends in the US: 1990-1998 Visceral obesity and metabolic syndrome Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study Pathogenesis of NIDDM. The cost of diabetes mellitus and its impact on health spending in Mexico The projected health care burden of type 2 diabetes in the UK from Cost-effectiveness of intensive lifestyle changes or metformin in overweight, glucose-intolerant patients: modelling the long-term implications of the diabetes prevention Program in the French, German and UK settings Costs associated with the primary prevention of type 2 diabetes mellitus in the diabetes prevention program Descriptive epidemiology of non-insulin dependent diabetes mellitus detected by urine glucose screening in school children in Japan US public health and the 21 st century: diabetes mellitus The diabetes risk score: a practical tool to predict type 2 diabetes DEHKO: Development programme for the prevention and care of diabetes in Finland
- keywords: age; americans; analysis; associated; burden; cardiovascular; care; children; clinical; complications; control; costs; countries; data; diabetes; diabetic; diagnosis; disease; epidemic; estimates; example; factors; fig; global; glucose; groups; health; healthcare; high; higher; impaired; increase; indian; insulin; intensive; management; mellitus; mortality; national; native; new; non; obesity; overweight; pacific; patients; people; population; prevalence; risk; study; subjects; syndrome; tolerance; total; treatment; type; undiagnosed; urban; usa; world; years
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- cord-294966-3jolt83r
- author: Joensen, L. E.
- title: Diabetes and COVID‐19: psychosocial consequences of the COVID‐19 pandemic in people with diabetes in Denmark—what characterizes people with high levels of COVID‐19‐related worries?
- date: 2020-05-29
- words: 4027
- flesch: 47
- summary: • Female gender, type 1 diabetes, diabetes complications, isolation, loneliness, high diabetes distress and behaviour changes were associated with being more worried about COVID-19 and diabetes. Our findings also showed that experiencing high diabetes distress and feeling lonely were related to experiencing COVID-19specific worries.
- keywords: anxiety; associated; care; changes; complications; coronavirus; covid-19; crisis; danish; denmark; diabetes; distress; feeling; general; group; health; high; information; items; levels; likely; loneliness; moderate; outbreak; pandemic; panels; participants; people; population; prevalence; psychological; psychosocial; questionnaire; questions; related; response; risk; scale; score; severe; social; sociodemographic; specific; status; study; support; time; type; worries
- versions: original; plain text
- cord-299637-6qarauys
- author: Assaloni, Roberta
- title: Coronavirus disease (Covid-19): how does the exercise practice in active people with Type 1 Diabetes change? A preliminary survey
- date: 2020-07-03
- words: 2583
- flesch: 38
- summary: PA level was investigated into pre-established days before the outbreak of Covid-19 disease and after the introduction of national quarantine . This study aims to explore PA level in PWT1D before and during quarantine and to describe variation in glycemia values.
- keywords: active; activity; control; coronavirus; covid-19; criteria; data; decrease; delivery; diabetes; disease; exercise; glucose; glycemia; godin; health; infections; insulin; italian; level; management; mean; medical; mellitus; national; particular; patients; people; period; physical; practice; pre; public; pwt1d; quarantine; risk; routine; sample; study; survey; training; type; values; worst
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- cord-304240-rqlfnywm
- author: Bloomgarden, Zachary
- title: Does glycemic control affect outcome of COVID‐19?
- date: 2020-10-03
- words: 690
- flesch: 42
- summary: Conceptually, several sets of mediators of adverse COVID-19 outcome may exist among persons with diabetes (Box 1). 1 We define diabetes by the presence of hyperglycemia, but we also know that, even among persons not known to have diabetes, the development of hyperglycemia in the setting of infection, trauma, surgery, or a cardiovascular event is associated with adverse outcome.
- keywords: adverse; covid-19; data; diabetes; hba1c; hyperglycemia; mortality; outcome; persons; population; type
- versions: original; plain text
- cord-305405-me4gebvm
- author: Conway, J.
- title: Characteristics of patients with diabetes hospitalised for COVID-19 infection-a brief case series report
- date: 2020-09-21
- words: 3187
- flesch: 45
- summary: The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) -China Impact of diabetes mellitus on clinical outcomes in patients affected by Covid-19 Outcomes in Patients With Hyperglycemia Affected by COVID-19: Can We Do More on Glycemic Control? Hyperglycaemia on admission to hospital and COVID-19 Negative impact of hyperglycaemia on tocilizumab therapy in Covid-19 patients Hypertension, Thrombosis, Kidney Failure, and Diabetes: Is COVID-19 an Endothelial Disease? key: cord-305405-me4gebvm authors: Conway, J.; Gould, A.; Westley, R.; Raju, S.; Oklopcic, A.; Broadbent, A.; Abdelhafiz, AH.; Sinclair, AJ. title: Characteristics of patients with diabetes hospitalised for COVID-19 infection-a brief case series report date: 2020-09-21 journal: Diabetes Res Clin Pract DOI: 10.1016/j.diabres.2020.108460 sha: doc_id: 305405 cord_uid: me4gebvm Objectives Diabetes has been shown to be a risk factor for corona virus disease-2019 (COVID-19) infection.
- keywords: ace; age; angiotensin; anti; arbs; case; characteristics; chinese; chronic; clinical; cohort; common; comorbidities; coronavirus; covid-19; data; diabetes; difference; disease; duration; frailty; higher; hospital; hyperglycaemia; hypertension; icu; infected; infection; inflammatory; inhibitors; kidney; mean; medical; obese; obesity; outcomes; patients; period; prevalence; risk; study; viral; years
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- cord-306670-c2jm0g88
- author: Zhang, Yan
- title: Association of Diabetes Mellitus with Disease Severity and Prognosis in COVID-19: A Retrospective Cohort Study
- date: 2020-05-22
- words: 3136
- flesch: 38
- summary: Other laboratory findings showed no significant differences between the two groups of patients with respect to serum levels of CRP, PCT, and LDH, but COVID-19 patients Next, we compared the severity, treatment, and short-term prognosis of the COVID-19 patients with and without diabetes in Table 3 . The laboratory findings on admission showed that leucocytes and neutrophils count and the proportion of increased leucocytes were higher in COVID-19 patients with diabetes than those without, which might be explained by the fact that patients with diabetes were more susceptible to pathogens after a viral infection due to lower immune function.
- keywords: acute; adjusted; admission; blood; cells; characteristics; china; chronic; clinical; control; coronavirus; count; cov-2; covid-19; covid-19 patients; data; diabetes; disease; eosinophil; fbg; findings; glucose; higher; hospital; ill; immune; infection; injury; laboratory; mellitus; mortality; novel; outcomes; patients; prevalence; prognosis; ratio; respiratory; risk; sars; severe; severity; study; term; therapy; treatment; wuhan
- versions: original; plain text
- cord-309474-9h9w46eq
- author: Schiaffini, Riccardo
- title: School and pre-school children with type 1 diabetes during covid-19 quarantine: the synergic effect of parental care and technology
- date: 2020-07-03
- words: 2515
- flesch: 41
- summary: key: cord-309474-9h9w46eq authors: Schiaffini, Riccardo; Barbetti, Fabrizio; Rapini, Novella; Inzaghi, Elena; Deodati, Annalisa; Patera, Ippolita P; Matteoli, Maria C; Ciampalini, Paolo; Carducci, Chiara; Lorubbio, Antonella; Schiaffini, Gabriele; Cianfarani, Stefano title: School and pre-school children with type 1 diabetes during covid-19 quarantine: the synergic effect of parental care and technology date: 2020-07-03 journal: Diabetes Res Clin Pract DOI: 10.1016/j.diabres.2020.108302 sha: doc_id: 309474 cord_uid: 9h9w46eq Abstract Introduction Management of Type 1 Diabetes (T1D) poses numerous challenges, especially for young children and their families. Parents of kindergartner (pre-school) and school children reported that the use of remote monitoring and CGM was effective in control glucose excursions 8.
- keywords: basal; care; cgm; children; control; cov; covid-19; data; day; diabetes; glucose; glycemic; insulin; life; management; monitoring; outcomes; pandemic; parental; parents; patients; period; pre; range; real; school; significant; study; system; t1d; tandem; teachers; technology; time; type; use; young
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- cord-309795-2kozsv4z
- author: Dewidar, Bedair
- title: Metabolic liver disease in diabetes – from mechanisms to clinical trials
- date: 2020-06-20
- words: 8655
- flesch: 28
- summary: The Liver The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD) Role of diet and lifestyle changes in nonalcoholic fatty liver disease Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance The integrative biology of type 2 diabetes Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance Anti-inflammatory effects of excessive weight loss: potent suppression of adipose interleukin 6 and tumour necrosis factor alpha expression Potential Nexus of Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus: Insulin Resistance Between Hepatic and Peripheral Tissues Insulin resistance causes inflammation in adipose tissue Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling Serum adiponectin levels in different types of non alcoholic liver disease. BL, baseline; CCR2/5, C-C chemokine receptors type 2 and type 5; FXR, farnesoid X receptor; HbA 1c , glycated haemoglobin; LXR, Liver X receptor; MPC, mitochondrial pyruvate carrier; NA, data not available; NAFLD, non-alcoholic fatty liver disease; NFS, NAFLD fibrosis score; PPAR, peroxisome proliferator-activated receptor; NASH, non-alcoholic steatohepatitis; SCD, stearoyl-CoA desaturase; SGLT, sodium-glucose cotransporter; THR, thyroid hormone receptor; T2DM, type 2 diabetes.
- keywords: acid; activated; activation; activity; adipose; agonist; alcoholic fatty; alterations; analysis; association; autophagy; beneficial; bile; biomarkers; blind; cardiovascular; cells; cirrhosis; clinical; coa; content; death; diabetes; diagnostic; diet; disease; dnl; double; drug; effects; efficacy; expression; fatty; fatty liver; ffa; fibrosis; fxr; glp-1; gluconeogenesis; glucose; guidelines; gut; hepatic; hepatocellular; hepatocytes; high; higher; hscs; humans; individuals; inflammation; inflammatory; inhibition; insulin; insulin resistance; intestinal; levels; lipid; lipogenesis; liver; liver disease; liver fibrosis; loss; mechanisms; mellitus; metabolic; metformin; mice; microbiome; mitochondrial; models; muscle; nafld; nash; non; nonalcoholic; nonalcoholic fatty; novel; obese; obesity; outcomes; patients; people; persons; phase; pioglitazone; placebo; plasma; ppar; progression; protein; randomized; recent; receptor; related; resistance; resolution; results; review; risk; signaling; specific; steatohepatitis; steatosis; stress; studies; study; surgery; systematic; t2 dm; table; tissue; treatment; trial; type; use; weight
- versions: original; plain text
- cord-309799-fhkbcp7z
- author: Hwang, Yerin
- title: Diabetes and COVID-19: IDF perspective in the Western Pacific Region
- date: 2020-06-25
- words: 2781
- flesch: 40
- summary: These include seven versions of the diagnosis and treatment protocol, three editions of the protocol for severe and critical cases, two editions of the manual for mild case management, two editions of convalescent plasma therapy treatment protocol, and one rehabilitation treatment program for patients discharged from hospitals 7 . 3) Japan -Since early April 2020 with the sharp increase in the number of COVID-19 cases, the health care systems in Japan has barely evaded collapse by ramping up the number of hospital beds dedicated to those with the disease (more than 12,000 beds nationwide) as well as by reallocating medical resources. However, by March 21 st 2020, when COVID-19 positive cases in Australia exceeded 1,000 with 7 deaths, Australia was clearly on the exponential part of the curve 6 .
- keywords: australia; beds; blood; care; cases; centers; china; clinics; covid-19; diabetes; disease; diverse; early; emergency; facilities; glucose; government; health; hospitals; insulin; japan; measures; medical; mild; national; number; outcomes; pacific; pandemic; patients; people; positive; region; research; resources; risk; screening; separate; services; severe; supply; support; taiwan; total; treatment; western; wpr; wuhan
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- cord-310159-l9hfmmbc
- author: Chowdhury, Subhankar
- title: COVID-19 and type 1 diabetes: dealing with the difficult duo
- date: 2020-07-14
- words: 3572
- flesch: 41
- summary: Possible explanations for the same include a younger age of T1D patients, lower prevalence of T1D, and overexpression of CD8+ T lymphocytes in T1D which might play a protective role (CD8+ T lymphocytes show an increased apoptosis leading to lymphocytopenia in SARS-COV2 infection) However, population cohort studies covering all individuals registered with a general practice in England show that T1D patients do contract COVID-19 infection requiring hospitalisation in some [14, 15] .
- keywords: activity; care; children; china; chloroquine; control; coronavirus; covid-19; development; diabetes; disease; dka; dose; effect; evidence; general; global; glucose; glycemic; hospital; hydroxychloroquine; hypoglycemia; icu; individuals; infection; insulin; levels; lockdown; management; monitoring; mortality; necessary; need; outcomes; pandemic; patients; people; physical; population; practice; prevalence; regular; report; respiratory; review; risk; sars; severe; studies; study; symptoms; system; t1d; type; viral
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- cord-310650-8lhkiw9p
- author: Gamble, Anissa
- title: The Challenges of COVID-19 for People Living With Diabetes: Considerations for Digital Health
- date: 2020-05-15
- words: 2089
- flesch: 40
- summary: Despite the positive enablers for remote diabetes care, the ability to share diabetes device data back to the clinic remains a challenge [46] . It continues to be a challenge to convince manufacturers of diabetes devices and EHR vendors to create truly interoperable systems to ease the burden on the diabetes communities
- keywords: access; care; challenges; clinic; clinical; community; control; coronavirus; covid-19; data; device; diabetes; digital; disease; global; glycemic; greater; health; impact; infection; insulin; management; pandemic; patients; people; person; risk; self; services; severity; significant; type; url; use; virtual; visits; world
- versions: original; plain text
- cord-312875-gn6hg6oc
- author: Infante, Marco
- title: Antihyperglycemic properties of hydroxychloroquine in patients with diabetes: risks and benefits at the time of COVID‐19 pandemic
- date: 2020-05-13
- words: 4851
- flesch: 25
- summary: The aim of this manuscript is to comprehensively summarize the current knowledge on the antihyperglycemic properties of HCQ and to critically evaluate the potential risks and benefits related to HCQ use in patients with diabetes, even in light of the current pandemic scenario. Besides the well-known contraindications to HCQ use (including known hypersensitivity to 4aminoquinoline compounds), (2, 44) other conditions or circumstances under which HCQ should be contraindicated or used with caution in the context of diabetes include the following: Pre-existing retinopathy/maculopathy, history or risk for macular edema, and concomitant use of other oculo-toxic agents.
- keywords: agent; anti; article; baseline; beta; cells; clearance; clinical; copyright; coronavirus; covid-19; day; dependent; diabetes; diabetic; disease; dose; drug; effects; efficacy; fasting; glucose; hcq; hepatic; hydroxychloroquine; hypoglycemic; improvement; increase; india; inflammation; inflammatory; insulin; levels; mechanisms; mellitus; non; pandemic; patients; placebo; potential; pre; properties; randomized; reduction; resistance; rheumatic; rights; risk; safety; secretion; sensitivity; severe; significant; studies; study; subjects; systemic; t2d; therapy; treatment; trial; type; use
- versions: original; plain text
- cord-313829-pjscmen8
- author: Caballero, A.E.
- title: COVID-19 in people living with diabetes: An international consensus
- date: 2020-07-06
- words: 4359
- flesch: 45
- summary: A statement from the Diabetes in COVID-19: prevalence, pathophysiology, prognosis and practical considerations Predicting mortality due to SARS-CoV-2: a mechanistic score relating obesity and diabetes to COVID-19 outcomes in Diabetes and COVID-19: more than the sum of two morbidities Diabetic patients with COVID-19 infection are at higher risk of ICU admission and poor short-term outcome Covid-19: The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China Expert recommendations for diabetes management in primary care during the COVID-19 pandemic Guidance on diabetes management in the elderly during the COVID-19 pandemic Recommendations on insulin treatment in diabetes patients affected with COVID-19 COVID-19 weekly surveillance report: data for the week of 8 -14 World Health Organization.
- keywords: access; ace2; associated; available; better; blood; care; cases; clinical; control; coronavirus; countries; country; cov-2; covid-19; data; diabetes; disaster; disease; epidemic; factors; glucose; glycemic; health; high; hospital; hyperglycemia; increase; india; insulin; lockdown; lower; management; medications; model; mortality; outcomes; pandemic; patients; people; plwd; population; prevalence; r n; ramadan; recent; recommendations; related; resistance; risk; sars; severe; situation; u r; u.s; use; world; years
- versions: original; plain text
- cord-314500-89ovdnxl
- author: Dunachie, Susanna
- title: The double burden of diabetes and global infection in low and middle-income countries
- date: 2018-12-04
- words: 5812
- flesch: 33
- summary: There is a lack of evidence on which to base guidelines for people living in LMIC, and choice of glucose-lowering therapy may impact on infection risk and outcomes. More than half of the world's TB cases occur in five countries, 15 which have significant prevalence rates and total numbers of diabetes cases in adults aged 20-79 years as follows: China (10.9%, 114 million), India (8.8%, 73 million), Indonesia (6.2%, 10 million), Philippines (6.2%, 3.7 million) and Pakistan (6.9%, 7.5 million).
- keywords: acute; adults; analysis; burden; cases; cells; changes; chronic; clinical; control; countries; current; death; dengue; development; diabetes; diabetes mellitus; diabetic; disease; epidemiology; evidence; factor; function; global; group; health; helminth; hepatitis; high; higher; hiv; hospital; hyperglycaemia; immune; impact; income; increase; infection; influenza; insulin; international; intracellular; lack; lmic; low; malaria; mechanisms; melioidosis; mellitus; meta; middle; mortality; neglected; non; number; outcomes; patients; people; population; prevalence; prospective; pseudomallei; pyomyositis; rates; relationship; research; resistance; responses; review; risk; severe; studies; study; susceptibility; systematic; therapy; treatment; tropical; tuberculosis; type; virus; world
- versions: original; plain text
- cord-316943-ef3i96bo
- author: Sciberras, Justine
- title: The burden of type 2 diabetes pre-and during the COVID-19 pandemic – a review
- date: 2020-10-19
- words: 4871
- flesch: 41
- summary: Coronavirus infections and type 2 diabetes-shared pathways with therapeutic implications Renin-angiotensin system inhibitors improve the clinical outcomes of COVID-19 patients with hypertension Spe ci a l R e p or t Renin -Angiotensin -Aldosterone System Inhibitors in Patients with Covid-19 The use of renin angiotensin system inhibitor on mortality in patients with coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis Continued In-Hospital Angiotensin-Converting Enzyme Inhibitor and Angiotensin II Receptor Blocker Use in Hypertensive COVID-19 Patients Is Associated With Positive Clinical Outcome COVID-19 panic, solidarity and equity-the Malta exemplary experience Enforced inactivity in the elderly and diabetes risk: initial estimates of the burden of an unintended consequence of COVID-19 lockdown, medRxiv Clinical aspects of physical exercise for diabetes/metabolic syndrome Prevalence of obesity in Malta World Health Organization How do we identify people at high risk of type 2 diabetes and help prevent the condition from developing World Health Organization noncommunicable diseases country profiles Socioeconomic status and prevalence of type 2 diabetes in mainland China, Hong Kong and Taiwan: a systematic review Prevalence of diabetes and prediabetes in 15 states of India: results from the ICMR-INDIAB population-based cross-sectional study COVID-19 pandemic, coronaviruses, and diabetes mellitus Factors leading to high morbidity and mortality of COVID-19 in patients with type 2 diabetes Endocrine and metabolic link to coronavirus infection Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS COVID-19 and diabetes: The why, the what and the how Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensinconverting enzyme 2 COVID-19, renin-angiotensin system and endothelial dysfunction Outcomes in patients with COVID-19 infection taking ACEI/ARB Preventing a covid-19 pandemic Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?
- keywords: ace2; acute; additional; analysis; angiotensin; available; burden; changes; china; control; coronavirus; countries; country; covid-19; diabetes; diabetic; disease; economic; effects; enzyme; exercise; factors; global; glucose; health; healthcare; higher; impact; increase; individuals; infection; known; levels; life; lifestyle; lockdown; management; material; mechanisms; mellitus; meta; morbidity; mortality; national; obesity; outcomes; pandemic; patients; people; physical; plans; population; pre; public; receptor; recommendations; review; risk; sars; self; services; sleep; studies; study; supplementary; syndrome; system; systematic; type; use; vitamin; world; years
- versions: original; plain text
- cord-333487-zem2d4y6
- author: Thomaz Ugliara Barone, Mark
- title: The Impact of COVID-19 on People with Diabetes in Brazil
- date: 2020-07-03
- words: 4659
- flesch: 41
- summary: The Lancet The Silver Lining to COVID-19: Avoiding Diabetic Ketoacidosis Admissions with Telehealth Coronavirus Infections and Type 2 Diabetes -Shared Pathways with Therapeutic Implications Ensuring people-centred diabetes care during the COVID-19 pandemic Experiences from Portugal Beyond the virus: Additionally, announced measures for prevention and mitigation of COVID-19 consequences on this population, such as supply of medicines for 3 months, worked just for a minority.
- keywords: access; activity; age; america; analysis; authors; blood; brazil; brazilian; cardiovascular; care; case; changes; china; close; country; cov-2; covid-19; covid-19 pandemic; data; diabetes; disease; factors; figure; food; glucose; glycemic; group; habits; health; higher; home; impact; increase; individuals; infected; infection; international; italy; levels; measures; medical; medicines; mortality; ncds; number; pandemic; patients; people; physical; population; present; private; public; questions; respondents; response; risk; sars; severity; study; supplies; survey; t1d; t2d; testing; type
- versions: original; plain text
- cord-334582-ccg27nmf
- author: Bonora, Benedetta Maria
- title: Glycaemic Control Among People with Type 1 Diabetes During Lockdown for the SARS-CoV-2 Outbreak in Italy
- date: 2020-05-11
- words: 3848
- flesch: 45
- summary: We report the impact of these restrictions on glucose control among people with type 1 diabetes (T1D). What was learned from the study? Individuals with T1D who stopped working during lockdown significantly improved their glucose control while those who continued working (essential services) showed no change in glucose control.
- keywords: activities; average; clinic; control; coronavirus; cov-2; covid-19; data; deviation; diabetes; disease; effects; flash; glucose; glycaemic; home; hypoglycaemia; impact; individuals; insulin; italy; lockdown; management; monitoring; number; outbreak; patients; people; period; pump; range; sars; scans; sensor; services; spread; standard; stress; study; t1d; term; therapy; time; type; use; week; working
- versions: original; plain text
- cord-334773-yw2qgv13
- author: Lisco, Giuseppe
- title: Hypothesized mechanisms explaining poor prognosis in type 2 diabetes patients with COVID-19: a review
- date: 2020-08-10
- words: 7912
- flesch: 27
- summary: Unfortunately, inconclusive deductions are currently available for considering concomitant medications favourable (as well as detrimental) factors in COVID-19 patients with T2D. Despite some putative mechanisms have been identified and some speculative hypothesis have also been formulated indicating that some anti-diabetes medications may improve clinical course in COVID-19 (pioglitazone, gliflozins, DPP-IV inhibitors, GLP-1RA), further studies are needed to clarify the issue. Considering that pancreatic islets express ACE 2 , glucose impairment in COVID-19 diabetic patients could be attributable to a partial insulin deficiency
- keywords: ace; ace2; activation; activity; acute; addition; adipose; analysis; angiotensin; animal; attributable; baseline; cardiovascular; care; case; cells; characteristics; china; chronic; clinical; comorbidities; complications; control; coronavirus; course; cov-2; covid-19; cytokine; data; death; diabetes; diabetic; disease; distress; dysfunction; effects; elderly; endothelial; epidemiological; expression; factor; failure; glucose; greater; heart; high; higher; hospitalization; hospitalized; human; hyperglycaemia; hypertension; ill; immune; increase; infected; infection; inflammation; inflammatory; injury; innate; insulin; intensive; kidney; leading; levels; like; low; lower; lung; management; mechanisms; medications; mellitus; mortality; novel; obese; obesity; outcomes; pandemic; patients; people; pneumonia; poor; potential; prevalence; prognosis; progression; pulmonary; rate; receptor; renal; respiratory; response; retrospective; review; risk; role; sars; severe; study; syndrome; system; systemic; t2d; tissue; transmission; treatment; type; use; viral; worse; wuhan
- versions: original; plain text
- cord-335894-6m0nnufu
- author: Ceriello, Antonio
- title: Issues for the management of people with diabetes and COVID-19 in ICU
- date: 2020-07-20
- words: 4150
- flesch: 38
- summary: The measurement of D-dimer is very useful in the prediction of the risk for a thrombotic event and its evaluation has been suggested regarding the management of COVID-19 patients [55, 56] . The REasons for Geographic and Racial Differences in Stroke (REGARDS) Study Coagulation activation in diabetes mellitus: the role of hyperglycaemia and therapeutic prospects Hyperglycemia-induced thrombin formation in diabetes The possible role of oxidative stress Low molecular weight heparin restores antithrombin III activity from hyperglycemia induced alterations Incremental role of glycaemic variability over HbA1c in identifying type 2 diabetic patients with high platelet reactivity undergoing percutaneous coronary intervention Inflammageing and metaflammation: the yin and yang of type 2 diabetes Acute hyperglycaemia: a 'new' risk factor during myocardial infarction Oscillating glucose is more deleterious to endothelial function and oxidative stress than mean glucose in normal and type 2 diabetic patients Scientific Document Group: 2019 ESC guidelines on diabetes, prediabetes, and cardiovascular diseases developed in collaboration with the EASD Considerations for statin therapy in patients with COVID-19 Tissue specific up regulation of ACE2 in rabbit model of atherosclerosis by atorvastatin: role of epigenetic histone modifications Effect of pravastatin on the frequency of ventilator-associated pneumonia and on intensive care unit mortality: open-label, randomized study Association of elevated plasma interleukin-18 level with increased mortality in a clinical trial of statin treatment for acute respiratory distress syndrome Type 1 diabetes and cardiovascular disease Higher glucose variability in type 1 than in type 2 diabetes patients admitted to the intensive care unit: a retrospective cohort study Searching the reason of a lower aggressiveness of the CoronaVirus disease in Type 1 Diabetes COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options Diabetes and Cardiovascular Disease (D&CVD) EASD Study Group, et al.
- keywords: acute; angiotensin; association; blockers; cardiac; cardiovascular; care; case; clinical; complications; control; converting; coronavirus; cov-2; covid-19; diabetes; diabetic; disease; evaluation; glucose; glycemic; heart; high; hyperglycemia; icu; ill; increase; inhibitors; insulin; intensive; management; monitoring; mortality; needs; new; optimal; outcomes; patients; people; present; probnp; prognosis; receptor; risk; sars; severe; situation; statins; study; syndrome; therapy; treatment; troponin; type; unit; use; variability
- versions: original; plain text
- cord-336201-fl606l3b
- author: Daryabor, Gholamreza
- title: The Effects of Type 2 Diabetes Mellitus on Organ Metabolism and the Immune System
- date: 2020-07-22
- words: 13880
- flesch: 25
- summary: The endocrine part is made of different cell types, including α, β, δ, and ε cells that secrete glucagon, insulin, somatostatin, and ghrelin hormones, respectively. A humanin analog decreases oxidative stress and preserves mitochondrial integrity in cardiac myoblasts Humanin prevents high glucose-induced monocyte adhesion to endothelial cells by targeting KLF2 Novel clearance mechanisms of platelets Flow cytometric analysis of platelets type 2 diabetes mellitus reveals 'angry' platelets Platelet activity and hypercoagulation in type 2 diabetes Increased circulating resistin is associated with insulin resistance, oxidative stress and platelet activation in type 2 diabetes mellitus Increased levels of soluble adhesion molecules in type 2 (non-insulin dependent) diabetes mellitus are independent of glycaemic control Molecular mechanisms underpinning microparticle-mediated cellular injury in cardiovascular complications associated with diabetes Association between mean platelet volume in the pathogenesis of type 2 diabetes mellitus and diabetic macrovascular complications in Japanese patients Increased erythrocyte-and platelet-derived microvesicles in newly diagnosed type 2 diabetes mellitus Type 2 diabetes and cardiovascular disease: have all risk factors the same strength? Advanced glycation end products induce a prothrombotic phenotype in mice via interaction with platelet CD36 Central role of the P2Y12 receptor in platelet activation Long non-coding RNA metallothionein 1 pseudogene 3 promotes p2y12 expression by sponging miR-126 to activate platelet in diabetic animal model Introduction to the human gut microbiota Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection Faecalibacterium prausnitzii-derived microbial anti-inflammatory molecule regulates intestinal integrity in diabetes mellitus mice via modulating tight junction protein expression Considering gut microbiota in treatment of type 2 diabetes mellitus Metformin effect on gut microbiota: insights for HIV-related inflammation The bacterium Akkermansia muciniphila: a sentinel for gut permeability and its relevance to HIV-related inflammation High glucose decreases intracellular glutathione concentrations and upregulates inducible nitric oxide synthase gene expression in intestinal epithelial cells The role of iron in diabetes and its complications Hyperglycemia promotes microvillus membrane expression of DMT1 in intestinal epithelial cells in a PKCalpha-dependent manner Betacell deficit and increased beta-cell apoptosis in humans with type 2 diabetes Fatty acid-induced lipotoxicity in pancreatic beta-cells during development of type 2 diabetes Mesenchymal stem cell therapy in type 2 diabetes mellitus Establishment of insulin-producing cells from human embryonic stem cells underhypoxic condition for cell based therapy Human mesenchymal stem cell derived exosomes alleviate type 2 diabetes mellitus by reversing peripheral insulin resistance and relieving β-cell destruction A simple method for the generation of insulin producing cells from bone marrow mesenchymal stem cells Secretagogin affects insulin secretion in pancreatic beta-cells by regulating actin dynamics and focal adhesion Secretagogin regulates insulin signaling by direct insulin binding.
- keywords: ability; activation; activity; acute; adhesion; adipose; advanced; amyloid; anti; antibodies; apoptosis; associated; atherosclerosis; aureus; bacteria; beta; binding; blood; cardiovascular; cause; cd4; cells; chronic; complement; complications; conditions; control; coronavirus; cov-2; covid-19; cytokines; density; dependent; development; diabetes; diabetes mellitus; diabetic; diabetic patients; disease; dm patients; dysfunction; dyslipidemia; ecs; effects; elevated; endothelial; endothelial cells; essential; et al; expression; factors; fatty; figure; formation; functions; generation; glucose; glycation; gut; hba1c; healing; healthy; hepatocytes; high; higher; homeostasis; host; human; humoral; huvecs; hyperglycemia; ifn; il-6; immune; immunity; impaired; impairs; important; increase; individuals; induction; infections; inflammation; inflammatory; influenza; innate; insulin; integrity; intestinal; intracellular; islet; ldl; lectin; levels; lipid; liver; low; lymphoid; macrophages; main; manner; mechanisms; mellitus; metabolic; methylglyoxal; mgo; mice; microbiota; microparticles; mitochondrial; model; molecules; monocytes; mortality; muscle; neutrophils; nkg2d; nkt; non; normal; numbers; obese; obesity; organ; oxidative; pancreatic; pathogenesis; pathway; patients; phagocytosis; plasma; platelet; prevalence; production; products; progression; promote; protein; rats; reactive; receptor; reduced; resident; resistance; respiratory; response; risk; role; ros; sars; secretion; serum; signaling; skeletal; species; stress; studies; study; subsequent; surface; susceptibility; susceptible; syndrome; synthesis; system; t2 dm; tissue; tnf; tuberculosis; type; vascular; wound
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- cord-339637-hb6bsb6q
- author: Khader, Mohammed Abdul
- title: A cross sectional study reveals severe disruption in glycemic control in people with diabetes during and after lockdown in India
- date: 2020-08-18
- words: 3804
- flesch: 51
- summary: A pilot study from Government medical university reported 4880 teleconsultations were given by 38 ophthalmologists during COVID-19 lockdown in India However, since the start of unlocking and easing of restrictions from June 1 st , India is witnessing an exponential rise in COVID-19 cases indicating the possibility of 'community transmission' [2] .
- keywords: access; activity; age; analysis; bgls; care; cases; clinical; comorbidities; control; cov-2; covid-19; devices; diabetes; diabetics; digital; disruption; fig; food; glucometer; glycemic; habits; health; healthcare; home; impact; increase; india; infection; levels; lockdown; medical; medicines; ncds; pandemic; participants; patients; people; phase; physical; population; responses; risk; sars; services; severe; social; study; survey; treatment; virtual
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- cord-345360-wlzgq7f9
- author: Yan, Alice F.
- title: Perceived Risk, Behavior Changes and Health-related Outcomes During COVID-19 Pandemic: Findings among Adults with and without Diabetes in China
- date: 2020-07-22
- words: 3902
- flesch: 48
- summary: So far, it is unknown how Chinese diabetes patients perceived COVID-19 related risks and how they modified their health-related behaviors accordingly during the pandemic. To our knowledge, this study is the first sizeable nationwide survey to examine Chinese diabetics and healthy non-diabetic residents' attitudes towards COVID-19 risks and the impact of COVID-19 on health-related behavior changes, and self-related health during the home quarantine period in China.
- keywords: activity; adults; alcohol; behaviors; changes; characteristics; china; chinese; chronic; clinical; coronavirus; covid-19; current; data; diabetes; diabetic; disease; drinking; excellent; factors; findings; food; good; health; high; higher; increased; individuals; infection; lifestyle; likely; national; obesity; outcomes; pandemic; participants; patients; people; physical; prevalence; quarantine; related; reported; risk; sample; self; shortages; smoking; social; study; survey; type
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- cord-347207-1u4i6qmc
- author: Almomani, Huda Y.
- title: Randomised controlled trial of pharmacist-led patient counselling in controlling hypoglycaemic attacks in older adults with type 2 diabetes mellitus (rose-adam): A study protocol
- date: 2020-07-29
- words: 4461
- flesch: 47
- summary: Several studies have established the important positive role of educational interventions on achieving glycaemic control and other clinical outcomes, however, there is still a lack in studies that evaluate the impact of such type of interventions on hypoglycaemia risk in elderly patients with type 2 diabetes. 19 56 There are several studies on the association between hypoglycaemia and patient 57 characteristics such as patients' perspectives and attitudes towards diabetes management 58 skills, self-monitoring of blood glucose, and non-adherence to anti-diabetic medications in 59 Jordanian population.
- keywords: adults; analysis; anti; attacks; bias; blood; care; clinical; complications; control; counselling; data; diabetes; diabetic; educational; elderly; enrolment; evaluation; events; follow; glucose; group; handshake; health; hypoglycaemia; intervention; jordan; management; measure; medications; mellitus; number; older; older adults; outcomes; participants; patients; pharmacist; phone; process; protocol; randomised; related; research; review; severe; study; sugar; time; treatment; trial; type; use; variables; visit; weeks
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- cord-350182-s10nong7
- author: Milionis, Charalampos
- title: A brief analysis and hypotheses about the risk of COVID-19 for people with type 1 and type 2 diabetes mellitus
- date: 2020-07-20
- words: 2734
- flesch: 35
- summary: As of June 29, 2020, the number of COVID-19 infections globally has exceeded 10 million cases in 188 countries/regions causing more than 500,000 deaths [9] . Clinical and basic evidence Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Commentary.
- keywords: acute; analysis; cases; cells; chronic; clinical; control; coronavirus; cov-2; covid-19; cytokines; diabetes; diabetes mellitus; disease; factors; features; health; humans; hyperglycaemia; immune; immunity; individuals; infected; infections; inflammation; inflammatory; innate; insulin; mellitus; mers; novel; pathogenesis; patients; people; pro; production; respiratory; response; review; risk; sars; severe; spread; syndrome; system; type; viral; viruses
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- cord-350373-dftdxzsm
- author: Rayman, G.
- title: Dexamethasone therapy in COVID‐19 patients: implications and guidance for the management of blood glucose in people with and without diabetes
- date: 2020-08-02
- words: 1748
- flesch: 43
- summary: Patients on basal-bolus regimens may not require 'mealtime' insulin boluses if not eating, however, if hyperglycaemia persists during adjustment of basal insulin then use corrective rapid acting insulin doses according to total daily insulin dose (TDD) or weight given in the table for correction doses of rapid acting insulin Leicester Diabetes Centre › People on twice-daily pre-mix insulin e.g. Insulin resistance will fall when dexamethasone is stopped and so capillary blood glucose and insulin dose adjustment need careful monitoring to avoid hypoglycaemia.
- keywords: acting; blood; covid-19; daily; day; dexamethasone; diabetes; dose; glucose; guidance; guidelines; hyperglycaemia; insulin; management; metabolism; mmol; need; oxygen; patients; people; rapid; resistance; therapy
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- cord-352544-7b6btzrx
- author: Liu, Zhelong
- title: The association of diabetes and the prognosis of COVID-19 patients: a retrospective study
- date: 2020-08-25
- words: 3293
- flesch: 42
- summary: key: cord-352544-7b6btzrx authors: Liu, Zhelong; Bai, Xi; Han, Xia; Jiang, Wangyan; Qiu, Lin; Chen, Shi; Yu, Xuefeng title: The association of diabetes and the prognosis of COVID-19 patients: a retrospective study date: 2020-08-25 journal: Diabetes Res Clin Pract DOI: 10.1016/j.diabres.2020.108386 sha: doc_id: 352544 cord_uid: 7b6btzrx Abstract Aims This study evaluated the impact of previous glycemic control and in-hospital use of antidiabetic/antihypertensive drugs on the prognosis of COVID-19 patients with diabetes. Data regarding the impact of diabetes on the prognosis of COVID-19 patients are scant and controversial.
- keywords: admission; analysis; antidiabetic; antihypertensive; clinical; control; coronavirus; covid-19; covid-19 patients; data; diabetes; disease; drugs; glucose; glycemic; group; hba1c; higher; hospital; impact; maximum; metformin; model; mortality; odds; patients; poor; previous; prognosis; results; risk; sars; studies; study; syndrome; use; value; worsening
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- cord-353867-617f90wq
- author: Ory, Marcia G.
- title: Implementing a Diabetes Education Program to Reduce Health Disparities in South Texas: Application of the RE-AIM Framework for Planning and Evaluation
- date: 2020-08-30
- words: 6661
- flesch: 40
- summary: The majority of program participants were aged between 45 and 64 years (55.3%), female (61.6%), Hispanic (68.6%), and had high school or less education (72.2%). Table 2 shows the number and characteristics of overall program participants who attended and did not attend at each follow-up assessment.
- keywords: a1c; a1c level; ada; aim; analyses; average; baseline; biennia; biennium; changes; characteristics; clinical; community; control; counties; data; delivery; diabetes; diabetes education; disparities; education; education program; estimated; evaluation; example; follow; framework; health; healthcare; high; higher; impact; implementation; initiative; intervention; language; level; management; models; months; outcomes; participants; planning; population; pre; primary; program; public; rates; reach; regional; research; retention; review; second; second biennium; self; sessions; significant; sites; south; study; subsequent; sustainability; table; term; texas; time; type; ups; values; workshop
- versions: original; plain text